VAPA_1c02010 248f590d948c2575510d23bb8f2cb88f 462 SUPERFAMILY SSF51338 355 447 7.85E-10 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 VAPA_1c02010 248f590d948c2575510d23bb8f2cb88f 462 TIGRFAM TIGR02022 hutF: formiminoglutamate deiminase 1 456 9.0E-174 T 12-10-2018 IPR010252 Formiminoglutamate deiminase VAPA_1c02010 248f590d948c2575510d23bb8f2cb88f 462 SUPERFAMILY SSF51556 51 377 1.57E-68 T 12-10-2018 IPR032466 Metal-dependent hydrolase VAPA_1c02010 248f590d948c2575510d23bb8f2cb88f 462 Pfam PF01979 Amidohydrolase family 49 430 7.8E-32 T 12-10-2018 IPR006680 Amidohydrolase-related GO:0016787 VAPA_1c02010 248f590d948c2575510d23bb8f2cb88f 462 Gene3D G3DSA:2.30.40.10 9 436 2.9E-176 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 VAPA_1c02010 248f590d948c2575510d23bb8f2cb88f 462 Gene3D G3DSA:3.20.20.140 53 448 2.9E-176 T 12-10-2018 VAPA_1c29530 4d5e8742cc475a9219bf052d30b792a9 251 Pfam PF00318 Ribosomal protein S2 8 222 3.1E-88 T 12-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 VAPA_1c29530 4d5e8742cc475a9219bf052d30b792a9 251 TIGRFAM TIGR01011 rpsB_bact: ribosomal protein uS2 4 224 2.6E-93 T 12-10-2018 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 VAPA_1c29530 4d5e8742cc475a9219bf052d30b792a9 251 SUPERFAMILY SSF52313 5 228 3.79E-86 T 12-10-2018 IPR023591 Ribosomal protein S2, flavodoxin-like domain superfamily VAPA_1c29530 4d5e8742cc475a9219bf052d30b792a9 251 ProSitePatterns PS00962 Ribosomal protein S2 signature 1. 5 16 - T 12-10-2018 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 VAPA_1c29530 4d5e8742cc475a9219bf052d30b792a9 251 Gene3D G3DSA:3.40.50.10490 7 217 2.3E-83 T 12-10-2018 VAPA_1c29530 4d5e8742cc475a9219bf052d30b792a9 251 Hamap MF_00291_B 30S ribosomal protein S2 [rpsB]. 1 223 38.67 T 12-10-2018 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 VAPA_1c29530 4d5e8742cc475a9219bf052d30b792a9 251 PRINTS PR00395 Ribosomal protein S2 signature 173 184 6.9E-33 T 12-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 VAPA_1c29530 4d5e8742cc475a9219bf052d30b792a9 251 PRINTS PR00395 Ribosomal protein S2 signature 156 173 6.9E-33 T 12-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 VAPA_1c29530 4d5e8742cc475a9219bf052d30b792a9 251 PRINTS PR00395 Ribosomal protein S2 signature 86 103 6.9E-33 T 12-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 VAPA_1c29530 4d5e8742cc475a9219bf052d30b792a9 251 PRINTS PR00395 Ribosomal protein S2 signature 194 208 6.9E-33 T 12-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 VAPA_1c29530 4d5e8742cc475a9219bf052d30b792a9 251 PRINTS PR00395 Ribosomal protein S2 signature 5 23 6.9E-33 T 12-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 VAPA_1c29530 4d5e8742cc475a9219bf052d30b792a9 251 PRINTS PR00395 Ribosomal protein S2 signature 36 45 6.9E-33 T 12-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 VAPA_1c29530 4d5e8742cc475a9219bf052d30b792a9 251 Gene3D G3DSA:1.10.287.610 102 148 2.3E-83 T 12-10-2018 VAPA_1c30900 1c41f776dfdddc6eeef65f41ee536aa2 679 Gene3D G3DSA:3.40.50.970 333 543 8.7E-80 T 12-10-2018 VAPA_1c30900 1c41f776dfdddc6eeef65f41ee536aa2 679 TIGRFAM TIGR00232 tktlase_bact: transketolase 11 667 5.3E-273 T 12-10-2018 IPR005478 Transketolase, bacterial-like GO:0004802 KEGG: 00030+2.2.1.1|KEGG: 00710+2.2.1.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|MetaCyc: PWY-6901 VAPA_1c30900 1c41f776dfdddc6eeef65f41ee536aa2 679 SUPERFAMILY SSF52518 3 324 7.07E-117 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold VAPA_1c30900 1c41f776dfdddc6eeef65f41ee536aa2 679 SUPERFAMILY SSF52518 358 531 1.6E-67 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold VAPA_1c30900 1c41f776dfdddc6eeef65f41ee536aa2 679 Gene3D G3DSA:3.40.50.920 545 678 1.4E-39 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 VAPA_1c30900 1c41f776dfdddc6eeef65f41ee536aa2 679 ProSitePatterns PS00801 Transketolase signature 1. 17 37 - T 12-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 VAPA_1c30900 1c41f776dfdddc6eeef65f41ee536aa2 679 Pfam PF02779 Transketolase, pyrimidine binding domain 360 531 1.3E-47 T 12-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain VAPA_1c30900 1c41f776dfdddc6eeef65f41ee536aa2 679 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 10 338 7.3E-152 T 12-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 VAPA_1c30900 1c41f776dfdddc6eeef65f41ee536aa2 679 Gene3D G3DSA:3.40.50.970 8 330 1.0E-127 T 12-10-2018 VAPA_1c30900 1c41f776dfdddc6eeef65f41ee536aa2 679 Pfam PF02780 Transketolase, C-terminal domain 549 658 8.9E-12 T 12-10-2018 IPR033248 Transketolase, C-terminal domain VAPA_1c30900 1c41f776dfdddc6eeef65f41ee536aa2 679 ProSitePatterns PS00802 Transketolase signature 2. 473 489 - T 12-10-2018 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 VAPA_1c30900 1c41f776dfdddc6eeef65f41ee536aa2 679 SMART SM00861 361 531 4.3E-72 T 12-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain VAPA_1c30900 1c41f776dfdddc6eeef65f41ee536aa2 679 SUPERFAMILY SSF52922 539 668 2.88E-39 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 VAPA_1c23950 d397e89197d2c81429490aedacbf3b82 304 PIRSF PIRSF035875 1 295 1.9E-70 T 12-10-2018 IPR017039 Virulence factor BrkB VAPA_1c23950 d397e89197d2c81429490aedacbf3b82 304 Pfam PF03631 Virulence factor BrkB 22 276 2.5E-59 T 12-10-2018 IPR017039 Virulence factor BrkB VAPA_1c23950 d397e89197d2c81429490aedacbf3b82 304 TIGRFAM TIGR00765 yihY_not_rbn: YihY family inner membrane protein 17 273 9.7E-26 T 12-10-2018 IPR017039 Virulence factor BrkB VAPA_1c40920 11dba9041b2146edce550a1f983eea59 300 SUPERFAMILY SSF46785 7 109 2.12E-19 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c40920 11dba9041b2146edce550a1f983eea59 300 Gene3D G3DSA:1.10.10.10 3 90 1.6E-25 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c40920 11dba9041b2146edce550a1f983eea59 300 Pfam PF03466 LysR substrate binding domain 88 293 1.1E-43 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_1c40920 11dba9041b2146edce550a1f983eea59 300 SUPERFAMILY SSF53850 89 296 5.43E-45 T 12-10-2018 VAPA_1c40920 11dba9041b2146edce550a1f983eea59 300 Gene3D G3DSA:3.40.190.10 91 289 9.0E-63 T 12-10-2018 VAPA_1c40920 11dba9041b2146edce550a1f983eea59 300 Gene3D G3DSA:3.40.190.10 163 264 9.0E-63 T 12-10-2018 VAPA_1c40920 11dba9041b2146edce550a1f983eea59 300 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 62 2.1E-18 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_2c04300 f727f61817f8a645e00d795673334d97 450 Gene3D G3DSA:3.20.20.70 145 313 1.7E-121 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 VAPA_2c04300 f727f61817f8a645e00d795673334d97 450 SUPERFAMILY SSF54675 3 132 4.54E-43 T 12-10-2018 VAPA_2c04300 f727f61817f8a645e00d795673334d97 450 Gene3D G3DSA:3.20.140.10 5 372 1.7E-121 T 12-10-2018 VAPA_2c04300 f727f61817f8a645e00d795673334d97 450 PIRSF PIRSF000484 1 441 6.6E-119 T 12-10-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 VAPA_2c04300 f727f61817f8a645e00d795673334d97 450 Pfam PF04095 Nicotinate phosphoribosyltransferase (NAPRTase) family 149 327 1.9E-10 T 12-10-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 VAPA_2c04300 f727f61817f8a645e00d795673334d97 450 TIGRFAM TIGR01513 NAPRTase_put: nicotinate phosphoribosyltransferase 4 429 1.2E-141 T 12-10-2018 IPR006405 Nicotinate phosphoribosyltransferase pncB-type GO:0004516|GO:0019358 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264|Reactome: R-HSA-6798695 VAPA_2c04300 f727f61817f8a645e00d795673334d97 450 SUPERFAMILY SSF51690 133 436 1.47E-93 T 12-10-2018 IPR036068 Nicotinate phosphoribosyltransferase-like, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 VAPA_1c11120 d3655e2035d0a741f066f06893900ad8 748 Gene3D G3DSA:3.40.1190.10 483 723 1.0E-9 T 12-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 VAPA_1c11120 d3655e2035d0a741f066f06893900ad8 748 Gene3D G3DSA:3.30.470.20 381 479 1.7E-7 T 12-10-2018 VAPA_1c11120 d3655e2035d0a741f066f06893900ad8 748 Gene3D G3DSA:3.30.1490.20 223 313 8.0E-18 T 12-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 VAPA_1c11120 d3655e2035d0a741f066f06893900ad8 748 TIGRFAM TIGR02068 cya_phycin_syn: cyanophycin synthetase 9 732 1.6E-259 T 12-10-2018 IPR011810 Cyanophycin synthetase GO:0005524|GO:0009059|GO:0016874 MetaCyc: PWY-7052 VAPA_1c11120 d3655e2035d0a741f066f06893900ad8 748 SUPERFAMILY SSF53623 487 721 5.49E-12 T 12-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 VAPA_1c11120 d3655e2035d0a741f066f06893900ad8 748 SUPERFAMILY SSF56059 223 492 3.54E-31 T 12-10-2018 VAPA_1c11120 d3655e2035d0a741f066f06893900ad8 748 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 223 330 2.3E-10 T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 VAPA_1c34330 e5dffb7e6b3370e16d6f4aab8013cb7a 336 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 60 332 4.6E-87 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c34330 e5dffb7e6b3370e16d6f4aab8013cb7a 336 PIRSF PIRSF017082 8 335 6.8E-73 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c34330 e5dffb7e6b3370e16d6f4aab8013cb7a 336 Gene3D G3DSA:3.40.190.10 138 261 5.1E-106 T 12-10-2018 VAPA_1c34330 e5dffb7e6b3370e16d6f4aab8013cb7a 336 Gene3D G3DSA:3.40.190.150 41 326 5.1E-106 T 12-10-2018 VAPA_1c34330 e5dffb7e6b3370e16d6f4aab8013cb7a 336 SUPERFAMILY SSF53850 124 292 7.24E-10 T 12-10-2018 VAPA_1c35280 1dd2336642b4547efaa0f424cc37e368 176 SUPERFAMILY SSF52499 2 169 1.44E-39 T 12-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 VAPA_1c35280 1dd2336642b4547efaa0f424cc37e368 176 Pfam PF00857 Isochorismatase family 3 152 2.8E-33 T 12-10-2018 IPR000868 Isochorismatase-like GO:0003824 VAPA_1c35280 1dd2336642b4547efaa0f424cc37e368 176 Gene3D G3DSA:3.40.50.850 1 162 2.6E-39 T 12-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 VAPA_1c23370 218fe3d4db484432fad948a9017abecf 283 Hamap MF_01576 Bifunctional protein FolD [folD]. 3 282 38.315 T 12-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 VAPA_1c23370 218fe3d4db484432fad948a9017abecf 283 Gene3D G3DSA:3.40.50.10860 8 275 1.6E-111 T 12-10-2018 VAPA_1c23370 218fe3d4db484432fad948a9017abecf 283 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 255 273 2.4E-80 T 12-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 VAPA_1c23370 218fe3d4db484432fad948a9017abecf 283 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 238 254 2.4E-80 T 12-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 VAPA_1c23370 218fe3d4db484432fad948a9017abecf 283 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 74 101 2.4E-80 T 12-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 VAPA_1c23370 218fe3d4db484432fad948a9017abecf 283 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 33 55 2.4E-80 T 12-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 VAPA_1c23370 218fe3d4db484432fad948a9017abecf 283 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 203 232 2.4E-80 T 12-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 VAPA_1c23370 218fe3d4db484432fad948a9017abecf 283 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 109 130 2.4E-80 T 12-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 VAPA_1c23370 218fe3d4db484432fad948a9017abecf 283 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 154 174 2.4E-80 T 12-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 VAPA_1c23370 218fe3d4db484432fad948a9017abecf 283 Pfam PF00763 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain 5 120 9.1E-38 T 12-10-2018 IPR020630 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 VAPA_1c23370 218fe3d4db484432fad948a9017abecf 283 Pfam PF02882 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 124 281 5.4E-71 T 12-10-2018 IPR020631 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GO:0004488 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 VAPA_1c23370 218fe3d4db484432fad948a9017abecf 283 Gene3D G3DSA:3.40.50.720 6 258 1.6E-111 T 12-10-2018 VAPA_1c23370 218fe3d4db484432fad948a9017abecf 283 SUPERFAMILY SSF53223 1 121 3.64E-37 T 12-10-2018 VAPA_1c23370 218fe3d4db484432fad948a9017abecf 283 SUPERFAMILY SSF51735 122 280 7.2E-54 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c23370 218fe3d4db484432fad948a9017abecf 283 ProSitePatterns PS00766 Tetrahydrofolate dehydrogenase/cyclohydrolase signature 1. 75 100 - T 12-10-2018 IPR020867 Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site GO:0003824|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 VAPA_1c18950 8a3f79e98590492e3577f853eb9be8bc 90 Gene3D G3DSA:1.10.10.1100 1 54 4.0E-14 T 12-10-2018 VAPA_1c18950 8a3f79e98590492e3577f853eb9be8bc 90 Pfam PF04324 BFD-like [2Fe-2S] binding domain 2 49 4.8E-9 T 12-10-2018 IPR007419 BFD-like [2Fe-2S]-binding domain VAPA_1c11840 b132a88d213f47c5ca15d8903317abd1 253 SUPERFAMILY SSF53850 1 251 2.36E-62 T 12-10-2018 VAPA_1c11840 b132a88d213f47c5ca15d8903317abd1 253 Gene3D G3DSA:3.40.190.10 28 248 3.4E-58 T 12-10-2018 VAPA_1c11840 b132a88d213f47c5ca15d8903317abd1 253 Gene3D G3DSA:3.40.190.10 116 211 3.4E-58 T 12-10-2018 VAPA_1c11840 b132a88d213f47c5ca15d8903317abd1 253 SMART SM00062 28 253 6.9E-51 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF VAPA_1c11840 b132a88d213f47c5ca15d8903317abd1 253 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 29 250 2.6E-56 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF VAPA_1c11840 b132a88d213f47c5ca15d8903317abd1 253 SMART SM00079 28 253 3.6E-4 T 12-10-2018 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 VAPA_1c39020 a7f5084276bc3c370801f84ffaeb9fc2 211 Pfam PF02660 Glycerol-3-phosphate acyltransferase 14 197 7.3E-53 T 12-10-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 VAPA_1c39020 a7f5084276bc3c370801f84ffaeb9fc2 211 Hamap MF_01043 Glycerol-3-phosphate acyltransferase [plsY]. 9 206 20.969 T 12-10-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 VAPA_1c39020 a7f5084276bc3c370801f84ffaeb9fc2 211 SMART SM01207 12 198 2.6E-88 T 12-10-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 VAPA_1c39020 a7f5084276bc3c370801f84ffaeb9fc2 211 TIGRFAM TIGR00023 TIGR00023: acyl-phosphate glycerol 3-phosphate acyltransferase 8 207 7.6E-57 T 12-10-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 VAPA_1c17530 2ec1e2230fe8350b12b7a4d6ea819b01 277 TIGRFAM TIGR03284 thym_sym: thymidylate synthase 91 277 1.6E-87 T 12-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 VAPA_1c17530 2ec1e2230fe8350b12b7a4d6ea819b01 277 TIGRFAM TIGR03284 thym_sym: thymidylate synthase 9 91 8.2E-37 T 12-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 VAPA_1c17530 2ec1e2230fe8350b12b7a4d6ea819b01 277 PRINTS PR00108 Thymidylate synthase family signature 172 198 1.5E-47 T 12-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 VAPA_1c17530 2ec1e2230fe8350b12b7a4d6ea819b01 277 PRINTS PR00108 Thymidylate synthase family signature 210 227 1.5E-47 T 12-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 VAPA_1c17530 2ec1e2230fe8350b12b7a4d6ea819b01 277 PRINTS PR00108 Thymidylate synthase family signature 48 69 1.5E-47 T 12-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 VAPA_1c17530 2ec1e2230fe8350b12b7a4d6ea819b01 277 PRINTS PR00108 Thymidylate synthase family signature 121 140 1.5E-47 T 12-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 VAPA_1c17530 2ec1e2230fe8350b12b7a4d6ea819b01 277 PRINTS PR00108 Thymidylate synthase family signature 147 162 1.5E-47 T 12-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 VAPA_1c17530 2ec1e2230fe8350b12b7a4d6ea819b01 277 Gene3D G3DSA:3.30.572.10 7 277 1.2E-127 T 12-10-2018 IPR036926 Thymidylate synthase/dCMP hydroxymethylase superfamily KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 VAPA_1c17530 2ec1e2230fe8350b12b7a4d6ea819b01 277 ProSitePatterns PS00091 Thymidylate synthase active site. 132 160 - T 12-10-2018 IPR020940 Thymidylate synthase, active site GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 VAPA_1c17530 2ec1e2230fe8350b12b7a4d6ea819b01 277 Hamap MF_00008 Thymidylate synthase [thyA]. 7 277 39.018 T 12-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 VAPA_1c17530 2ec1e2230fe8350b12b7a4d6ea819b01 277 Pfam PF00303 Thymidylate synthase 9 277 3.7E-124 T 12-10-2018 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 VAPA_1c17530 2ec1e2230fe8350b12b7a4d6ea819b01 277 SUPERFAMILY SSF55831 4 277 1.57E-125 T 12-10-2018 IPR036926 Thymidylate synthase/dCMP hydroxymethylase superfamily KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 VAPA_1c45690 cf7ca4e1f71c465d8573549ce635aa04 153 Hamap MF_01885 tRNA (cytidine(34)-2'-O)-methyltransferase [trmL]. 2 153 32.398 T 12-10-2018 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 VAPA_1c45690 cf7ca4e1f71c465d8573549ce635aa04 153 TIGRFAM TIGR00185 tRNA_yibK_trmL: tRNA (cytidine(34)-2'-O)-methyltransferase 1 151 7.2E-59 T 12-10-2018 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 VAPA_1c45690 cf7ca4e1f71c465d8573549ce635aa04 153 PIRSF PIRSF029256 1 153 9.9E-64 T 12-10-2018 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 VAPA_1c45690 cf7ca4e1f71c465d8573549ce635aa04 153 Pfam PF00588 SpoU rRNA Methylase family 2 143 3.6E-30 T 12-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 VAPA_1c45690 cf7ca4e1f71c465d8573549ce635aa04 153 Gene3D G3DSA:3.40.1280.10 1 153 1.3E-64 T 12-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal VAPA_1c45690 cf7ca4e1f71c465d8573549ce635aa04 153 SUPERFAMILY SSF75217 1 151 1.7E-41 T 12-10-2018 IPR029028 Alpha/beta knot methyltransferases VAPA_1c19960 f2540f459319ac6e6abcaaf008aadd89 349 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 298 320 2.5E-7 T 12-10-2018 VAPA_1c19960 f2540f459319ac6e6abcaaf008aadd89 349 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 163 181 2.5E-7 T 12-10-2018 VAPA_1c19960 f2540f459319ac6e6abcaaf008aadd89 349 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 2.5E-7 T 12-10-2018 VAPA_1c19960 f2540f459319ac6e6abcaaf008aadd89 349 Gene3D G3DSA:3.50.50.60 1 349 2.4E-125 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c19960 f2540f459319ac6e6abcaaf008aadd89 349 Pfam PF13738 Pyridine nucleotide-disulphide oxidoreductase 6 192 8.6E-25 T 12-10-2018 VAPA_1c19960 f2540f459319ac6e6abcaaf008aadd89 349 SUPERFAMILY SSF51905 1 205 1.41E-39 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c19960 f2540f459319ac6e6abcaaf008aadd89 349 SUPERFAMILY SSF51905 163 345 2.41E-8 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c19960 f2540f459319ac6e6abcaaf008aadd89 349 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 159 183 2.8E-11 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 VAPA_1c19960 f2540f459319ac6e6abcaaf008aadd89 349 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 4 26 2.8E-11 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 VAPA_1c19960 f2540f459319ac6e6abcaaf008aadd89 349 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 120 128 2.8E-11 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 VAPA_1c23070 8726fd0af8b75e9842c9426dd4b29d3c 211 Gene3D G3DSA:1.10.15.40 4 52 4.9E-10 T 12-10-2018 VAPA_1c23070 8726fd0af8b75e9842c9426dd4b29d3c 211 TIGRFAM TIGR01944 rnfB: electron transport complex, RnfABCDGE type, B subunit 3 151 4.8E-55 T 12-10-2018 IPR010207 Ion-translocating oxidoreductase complex, RnfB/RsxB GO:0009055|GO:0051536 VAPA_1c23070 8726fd0af8b75e9842c9426dd4b29d3c 211 Gene3D G3DSA:3.30.70.20 53 148 2.5E-18 T 12-10-2018 VAPA_1c23070 8726fd0af8b75e9842c9426dd4b29d3c 211 SUPERFAMILY SSF54862 7 132 9.21E-25 T 12-10-2018 VAPA_1c23070 8726fd0af8b75e9842c9426dd4b29d3c 211 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 114 125 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site VAPA_1c23070 8726fd0af8b75e9842c9426dd4b29d3c 211 Pfam PF04060 Putative Fe-S cluster 12 44 3.3E-13 T 12-10-2018 IPR007202 4Fe-4S domain GO:0051536 VAPA_1c23070 8726fd0af8b75e9842c9426dd4b29d3c 211 PIRSF PIRSF005784 1 157 7.2E-54 T 12-10-2018 IPR016463 Electron transport complex, RnfB/RsxB, Proteobacteria GO:0005886|GO:0022900|GO:0051536 VAPA_1c23070 8726fd0af8b75e9842c9426dd4b29d3c 211 Pfam PF14697 4Fe-4S dicluster domain 77 130 9.3E-16 T 12-10-2018 VAPA_1c04920 e27b12599c6cecaa8e7c92a03ce3dd1f 495 Pfam PF00534 Glycosyl transferases group 1 302 455 1.0E-7 T 12-10-2018 IPR001296 Glycosyl transferase, family 1 VAPA_1c04920 e27b12599c6cecaa8e7c92a03ce3dd1f 495 Hamap MF_00484 Glycogen synthase [glgA]. 1 489 43.813 T 12-10-2018 IPR011835 Bacterial/plant glycogen synthase GO:0004373 KEGG: 00500+2.4.1.21|MetaCyc: PWY-622 VAPA_1c04920 e27b12599c6cecaa8e7c92a03ce3dd1f 495 TIGRFAM TIGR02095 glgA: glycogen/starch synthase, ADP-glucose type 1 488 4.4E-158 T 12-10-2018 IPR011835 Bacterial/plant glycogen synthase GO:0004373 KEGG: 00500+2.4.1.21|MetaCyc: PWY-622 VAPA_1c04920 e27b12599c6cecaa8e7c92a03ce3dd1f 495 Gene3D G3DSA:3.40.50.2000 3 486 3.0E-166 T 12-10-2018 VAPA_1c04920 e27b12599c6cecaa8e7c92a03ce3dd1f 495 Gene3D G3DSA:3.40.50.2000 259 471 3.0E-166 T 12-10-2018 VAPA_1c04920 e27b12599c6cecaa8e7c92a03ce3dd1f 495 SUPERFAMILY SSF53756 5 491 5.1E-111 T 12-10-2018 VAPA_1c04920 e27b12599c6cecaa8e7c92a03ce3dd1f 495 Pfam PF08323 Starch synthase catalytic domain 2 245 1.3E-72 T 12-10-2018 IPR013534 Starch synthase, catalytic domain KEGG: 00500+2.4.1.21|MetaCyc: PWY-622 VAPA_2c07310 73b04c1abd434074b9a16b977e7ccfd5 254 Hamap MF_00691 UPF0271 protein YbgL [ybgL]. 1 245 43.42 T 12-10-2018 IPR005501 UPF0271 family, LamB/YcsF/PxpA KEGG: 00480+3.5.2.9|MetaCyc: PWY-4041|MetaCyc: PWY-7942 VAPA_2c07310 73b04c1abd434074b9a16b977e7ccfd5 254 SUPERFAMILY SSF88713 1 246 2.59E-90 T 12-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 VAPA_2c07310 73b04c1abd434074b9a16b977e7ccfd5 254 Pfam PF03746 LamB/YcsF family 3 240 2.2E-92 T 12-10-2018 IPR005501 UPF0271 family, LamB/YcsF/PxpA KEGG: 00480+3.5.2.9|MetaCyc: PWY-4041|MetaCyc: PWY-7942 VAPA_2c07310 73b04c1abd434074b9a16b977e7ccfd5 254 Gene3D G3DSA:3.20.20.370 1 253 4.1E-94 T 12-10-2018 VAPA_1c36120 531b1da08640d3cb5cd7fafc86737097 720 ProSitePatterns PS00643 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 3. 146 156 - T 12-10-2018 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VAPA_1c36120 531b1da08640d3cb5cd7fafc86737097 720 ProSitePatterns PS00641 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 1. 31 48 - T 12-10-2018 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VAPA_1c36120 531b1da08640d3cb5cd7fafc86737097 720 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 1 76 2.8E-18 T 12-10-2018 VAPA_1c36120 531b1da08640d3cb5cd7fafc86737097 720 Gene3D G3DSA:3.30.70.20 125 205 1.3E-7 T 12-10-2018 VAPA_1c36120 531b1da08640d3cb5cd7fafc86737097 720 Pfam PF10588 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region 84 121 4.3E-16 T 12-10-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VAPA_1c36120 531b1da08640d3cb5cd7fafc86737097 720 SUPERFAMILY SSF54862 75 211 7.53E-36 T 12-10-2018 VAPA_1c36120 531b1da08640d3cb5cd7fafc86737097 720 Gene3D G3DSA:3.40.228.10 346 403 7.9E-17 T 12-10-2018 VAPA_1c36120 531b1da08640d3cb5cd7fafc86737097 720 SMART SM00929 83 123 4.3E-19 T 12-10-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VAPA_1c36120 531b1da08640d3cb5cd7fafc86737097 720 SUPERFAMILY SSF53706 214 654 1.96E-88 T 12-10-2018 VAPA_1c36120 531b1da08640d3cb5cd7fafc86737097 720 Pfam PF00384 Molybdopterin oxidoreductase 487 632 1.6E-16 T 12-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VAPA_1c36120 531b1da08640d3cb5cd7fafc86737097 720 Pfam PF00384 Molybdopterin oxidoreductase 273 405 1.3E-16 T 12-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VAPA_1c36120 531b1da08640d3cb5cd7fafc86737097 720 TIGRFAM TIGR01973 NuoG: NADH dehydrogenase (quinone), G subunit 4 631 3.9E-202 T 12-10-2018 IPR010228 NADH:ubiquinone oxidoreductase, subunit G GO:0016651|GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VAPA_1c36120 531b1da08640d3cb5cd7fafc86737097 720 SUPERFAMILY SSF54292 1 74 2.42E-19 T 12-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 VAPA_1c36120 531b1da08640d3cb5cd7fafc86737097 720 Gene3D G3DSA:3.40.50.740 281 345 7.9E-17 T 12-10-2018 VAPA_1c36120 531b1da08640d3cb5cd7fafc86737097 720 Gene3D G3DSA:3.40.50.740 421 665 4.5E-21 T 12-10-2018 VAPA_1c36120 531b1da08640d3cb5cd7fafc86737097 720 Gene3D G3DSA:3.10.20.740 1 123 4.8E-41 T 12-10-2018 VAPA_1c36120 531b1da08640d3cb5cd7fafc86737097 720 ProSitePatterns PS00642 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 2. 98 110 - T 12-10-2018 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VAPA_1c51590 b72140bc1634b6aabbc8211b9b905da0 344 Pfam PF01636 Phosphotransferase enzyme family 41 284 1.4E-38 T 12-10-2018 IPR002575 Aminoglycoside phosphotransferase VAPA_1c51590 b72140bc1634b6aabbc8211b9b905da0 344 Hamap MF_01497 Stress response kinase A [srkA]. 10 338 45.338 T 12-10-2018 IPR032882 SrkA/RdoA protein kinase GO:0004674|GO:0006468 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1 VAPA_1c51590 b72140bc1634b6aabbc8211b9b905da0 344 Gene3D G3DSA:1.10.510.10 66 278 3.5E-112 T 12-10-2018 VAPA_1c51590 b72140bc1634b6aabbc8211b9b905da0 344 Gene3D G3DSA:3.30.200.70 19 114 3.5E-112 T 12-10-2018 VAPA_1c51590 b72140bc1634b6aabbc8211b9b905da0 344 Gene3D G3DSA:1.20.1270.170 155 327 3.5E-112 T 12-10-2018 VAPA_1c51590 b72140bc1634b6aabbc8211b9b905da0 344 SUPERFAMILY SSF56112 12 342 1.12E-82 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily VAPA_1c17700 964dbec30f1ddbc032bbeba8773a86a7 330 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 53 327 1.3E-74 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c17700 964dbec30f1ddbc032bbeba8773a86a7 330 Gene3D G3DSA:3.40.190.150 35 321 1.1E-100 T 12-10-2018 VAPA_1c17700 964dbec30f1ddbc032bbeba8773a86a7 330 Gene3D G3DSA:3.40.190.10 132 256 1.1E-100 T 12-10-2018 VAPA_1c17700 964dbec30f1ddbc032bbeba8773a86a7 330 SUPERFAMILY SSF53850 117 291 8.32E-11 T 12-10-2018 VAPA_1c17700 964dbec30f1ddbc032bbeba8773a86a7 330 PIRSF PIRSF017082 1 330 1.3E-72 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c37000 dce5792cac6bd9bac45e98d0f5ecad88 471 Gene3D G3DSA:1.10.760.10 63 231 3.7E-42 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 VAPA_1c37000 dce5792cac6bd9bac45e98d0f5ecad88 471 SUPERFAMILY SSF46626 219 453 3.61E-27 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 VAPA_1c37000 dce5792cac6bd9bac45e98d0f5ecad88 471 SUPERFAMILY SSF46626 67 226 4.0E-29 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 VAPA_1c37000 dce5792cac6bd9bac45e98d0f5ecad88 471 Pfam PF03150 Di-haem cytochrome c peroxidase 67 241 8.9E-35 T 12-10-2018 IPR004852 Di-haem cytochrome c peroxidase GO:0016491|GO:0055114 VAPA_1c09590 535040b0ae23cae094f52fb2bc9ba645 207 SUPERFAMILY SSF57716 167 205 2.0E-7 T 12-10-2018 VAPA_1c09590 535040b0ae23cae094f52fb2bc9ba645 207 TIGRFAM TIGR02420 dksA: RNA polymerase-binding protein DksA 88 196 2.5E-43 T 12-10-2018 IPR012784 RNA polymerase-binding transcription factor DksA GO:0008270 VAPA_1c09590 535040b0ae23cae094f52fb2bc9ba645 207 SUPERFAMILY SSF109635 67 166 1.12E-30 T 12-10-2018 IPR037187 DksA, N-terminal domain superfamily VAPA_1c09590 535040b0ae23cae094f52fb2bc9ba645 207 Pfam PF01258 Prokaryotic dksA/traR C4-type zinc finger 165 199 3.0E-10 T 12-10-2018 IPR000962 Zinc finger, DksA/TraR C4-type GO:0008270 VAPA_1c09590 535040b0ae23cae094f52fb2bc9ba645 207 ProSitePatterns PS01102 Prokaryotic dksA C4-type zinc finger. 170 194 - T 12-10-2018 IPR020458 Zinc finger, DksA/TraR C4-type conserved site VAPA_1c09590 535040b0ae23cae094f52fb2bc9ba645 207 Gene3D G3DSA:1.20.120.910 72 205 2.6E-35 T 12-10-2018 VAPA_1c09590 535040b0ae23cae094f52fb2bc9ba645 207 Hamap MF_00926 RNA polymerase-binding transcription factor DksA [dksA]. 84 206 27.614 T 12-10-2018 IPR012784 RNA polymerase-binding transcription factor DksA GO:0008270 VAPA_2c00960 c518c8c752a240278bc282a2f63aa780 263 ProSitePatterns PS00482 Dihydroorotase signature 1. 12 20 - T 12-10-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 VAPA_2c00960 c518c8c752a240278bc282a2f63aa780 263 ProSitePatterns PS00483 Dihydroorotase signature 2. 164 175 - T 12-10-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 VAPA_2c00960 c518c8c752a240278bc282a2f63aa780 263 Pfam PF01979 Amidohydrolase family 75 222 2.0E-5 T 12-10-2018 IPR006680 Amidohydrolase-related GO:0016787 VAPA_2c00960 c518c8c752a240278bc282a2f63aa780 263 Gene3D G3DSA:3.20.20.140 67 263 1.8E-51 T 12-10-2018 VAPA_2c00960 c518c8c752a240278bc282a2f63aa780 263 SUPERFAMILY SSF51556 4 262 1.72E-94 T 12-10-2018 IPR032466 Metal-dependent hydrolase VAPA_2c00960 c518c8c752a240278bc282a2f63aa780 263 Gene3D G3DSA:3.20.20.140 1 66 1.1E-14 T 12-10-2018 VAPA_1c12630 f66a4842f79bf53778264071f79620a5 196 Gene3D G3DSA:2.30.30.220 4 121 9.5E-47 T 12-10-2018 IPR036760 SspB-like superfamily VAPA_1c12630 f66a4842f79bf53778264071f79620a5 196 PIRSF PIRSF005276 137 196 380.0 T 12-10-2018 IPR007481 Stringent starvation protein B VAPA_1c12630 f66a4842f79bf53778264071f79620a5 196 PIRSF PIRSF005276 4 134 5.8E-48 T 12-10-2018 IPR007481 Stringent starvation protein B VAPA_1c12630 f66a4842f79bf53778264071f79620a5 196 SUPERFAMILY SSF101738 7 110 4.19E-44 T 12-10-2018 IPR036760 SspB-like superfamily VAPA_1c12630 f66a4842f79bf53778264071f79620a5 196 Pfam PF04386 Stringent starvation protein B 9 196 2.6E-34 T 12-10-2018 IPR007481 Stringent starvation protein B VAPA_1c14710 584733c4f097579b7c7064beeff6e6eb 1071 SUPERFAMILY SSF50249 39 124 1.21E-18 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold VAPA_1c14710 584733c4f097579b7c7064beeff6e6eb 1071 Pfam PF10150 Ribonuclease E/G family 120 389 4.7E-93 T 12-10-2018 IPR019307 RNA-binding protein AU-1/Ribonuclease E/G GO:0003723 VAPA_1c14710 584733c4f097579b7c7064beeff6e6eb 1071 SMART SM00316 37 118 5.0E-11 T 12-10-2018 IPR022967 RNA-binding domain, S1 VAPA_1c14710 584733c4f097579b7c7064beeff6e6eb 1071 Gene3D G3DSA:2.40.50.140 31 124 1.0E-32 T 12-10-2018 VAPA_1c14710 584733c4f097579b7c7064beeff6e6eb 1071 TIGRFAM TIGR00757 RNaseEG: ribonuclease, Rne/Rng family 14 423 7.5E-157 T 12-10-2018 IPR004659 Ribonuclease E/G GO:0003723|GO:0004540|GO:0006396 VAPA_1c14710 584733c4f097579b7c7064beeff6e6eb 1071 Pfam PF00575 S1 RNA binding domain 36 117 5.6E-12 T 12-10-2018 IPR003029 S1 domain GO:0003676 VAPA_1c14710 584733c4f097579b7c7064beeff6e6eb 1071 Hamap MF_00970 Ribonuclease E [rne]. 1 1037 32.338 T 12-10-2018 IPR028878 Ribonuclease E GO:0006396|GO:0008995 VAPA_1c14710 584733c4f097579b7c7064beeff6e6eb 1071 Gene3D G3DSA:3.40.1260.20 399 509 1.2E-35 T 12-10-2018 VAPA_1c32830 f99cf1eac43cc02f6751532b6d0b103b 2463 Pfam PF00501 AMP-binding enzyme 237 630 1.1E-94 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 VAPA_1c32830 f99cf1eac43cc02f6751532b6d0b103b 2463 SUPERFAMILY SSF47336 1757 1862 4.45E-12 T 12-10-2018 IPR036736 ACP-like superfamily VAPA_1c32830 f99cf1eac43cc02f6751532b6d0b103b 2463 Gene3D G3DSA:3.90.1150.10 1981 2395 4.1E-109 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 VAPA_1c32830 f99cf1eac43cc02f6751532b6d0b103b 2463 SUPERFAMILY SSF53901 835 1262 9.41E-77 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 VAPA_1c32830 f99cf1eac43cc02f6751532b6d0b103b 2463 ProSitePatterns PS00455 Putative AMP-binding domain signature. 375 386 - T 12-10-2018 IPR020845 AMP-binding, conserved site VAPA_1c32830 f99cf1eac43cc02f6751532b6d0b103b 2463 Gene3D G3DSA:3.30.300.30 626 727 1.2E-29 T 12-10-2018 VAPA_1c32830 f99cf1eac43cc02f6751532b6d0b103b 2463 ProSitePatterns PS00012 Phosphopantetheine attachment site. 765 780 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site VAPA_1c32830 f99cf1eac43cc02f6751532b6d0b103b 2463 Gene3D G3DSA:1.10.1200.10 1753 1835 2.3E-9 T 12-10-2018 IPR036736 ACP-like superfamily VAPA_1c32830 f99cf1eac43cc02f6751532b6d0b103b 2463 SMART SM00823 Phosphopantetheine attachment site 1763 1835 0.032 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 VAPA_1c32830 f99cf1eac43cc02f6751532b6d0b103b 2463 SMART SM00823 Phosphopantetheine attachment site 741 810 3.2E-4 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 VAPA_1c32830 f99cf1eac43cc02f6751532b6d0b103b 2463 Gene3D G3DSA:3.40.50.12780 228 623 9.9E-137 T 12-10-2018 VAPA_1c32830 f99cf1eac43cc02f6751532b6d0b103b 2463 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 1216 1328 5.0E-17 T 12-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 VAPA_1c32830 f99cf1eac43cc02f6751532b6d0b103b 2463 SUPERFAMILY SSF53383 2002 2404 7.82E-81 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase VAPA_1c32830 f99cf1eac43cc02f6751532b6d0b103b 2463 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 1095 1213 8.2E-36 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal VAPA_1c32830 f99cf1eac43cc02f6751532b6d0b103b 2463 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 838 1087 3.7E-66 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal VAPA_1c32830 f99cf1eac43cc02f6751532b6d0b103b 2463 Pfam PF00698 Acyl transferase domain 1363 1641 9.8E-54 T 12-10-2018 IPR014043 Acyl transferase VAPA_1c32830 f99cf1eac43cc02f6751532b6d0b103b 2463 Gene3D G3DSA:3.40.366.10 1361 1656 8.8E-130 T 12-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 VAPA_1c32830 f99cf1eac43cc02f6751532b6d0b103b 2463 Gene3D G3DSA:3.40.47.10 834 1266 5.1E-155 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 VAPA_1c32830 f99cf1eac43cc02f6751532b6d0b103b 2463 SUPERFAMILY SSF52151 1361 1639 1.83E-62 T 12-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase VAPA_1c32830 f99cf1eac43cc02f6751532b6d0b103b 2463 SUPERFAMILY SSF47336 735 852 3.53E-15 T 12-10-2018 IPR036736 ACP-like superfamily VAPA_1c32830 f99cf1eac43cc02f6751532b6d0b103b 2463 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1789 1804 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site VAPA_1c32830 f99cf1eac43cc02f6751532b6d0b103b 2463 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 258 655 7.8E-122 T 12-10-2018 IPR010071 Amino acid adenylation domain VAPA_1c32830 f99cf1eac43cc02f6751532b6d0b103b 2463 Gene3D G3DSA:3.30.70.3290 1279 1701 8.8E-130 T 12-10-2018 VAPA_1c32830 f99cf1eac43cc02f6751532b6d0b103b 2463 SUPERFAMILY SSF55048 1485 1545 2.22E-7 T 12-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding VAPA_1c32830 f99cf1eac43cc02f6751532b6d0b103b 2463 Pfam PF00202 Aminotransferase class-III 2017 2332 8.7E-45 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 VAPA_1c32830 f99cf1eac43cc02f6751532b6d0b103b 2463 Gene3D G3DSA:3.40.640.10 2053 2314 4.1E-109 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 VAPA_1c32830 f99cf1eac43cc02f6751532b6d0b103b 2463 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 1000 1016 - T 12-10-2018 IPR018201 Beta-ketoacyl synthase, active site VAPA_1c32830 f99cf1eac43cc02f6751532b6d0b103b 2463 Pfam PF13193 AMP-binding enzyme C-terminal domain 639 713 4.2E-9 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain VAPA_1c32830 f99cf1eac43cc02f6751532b6d0b103b 2463 Gene3D G3DSA:1.10.1200.10 728 815 8.4E-20 T 12-10-2018 IPR036736 ACP-like superfamily VAPA_1c32830 f99cf1eac43cc02f6751532b6d0b103b 2463 SMART SM00825 Beta-ketoacyl synthase 840 1266 5.9E-164 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain VAPA_1c32830 f99cf1eac43cc02f6751532b6d0b103b 2463 SUPERFAMILY SSF56801 196 754 4.58E-148 T 12-10-2018 VAPA_1c32830 f99cf1eac43cc02f6751532b6d0b103b 2463 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 1363 1652 3.5E-93 T 12-10-2018 IPR020801 Polyketide synthase, acyl transferase domain VAPA_1c32830 f99cf1eac43cc02f6751532b6d0b103b 2463 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 2214 2250 - T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 VAPA_1c32830 f99cf1eac43cc02f6751532b6d0b103b 2463 Gene3D G3DSA:3.30.559.30 5 223 1.8E-7 T 12-10-2018 VAPA_1c32830 f99cf1eac43cc02f6751532b6d0b103b 2463 Pfam PF00550 Phosphopantetheine attachment site 1765 1831 2.5E-9 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain VAPA_1c32830 f99cf1eac43cc02f6751532b6d0b103b 2463 Pfam PF00550 Phosphopantetheine attachment site 742 805 1.9E-11 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain VAPA_2c06970 77cd58b401eb19a2abd14bb62f48ab47 231 TIGRFAM TIGR02118 TIGR02118: conserved hypothetical protein 9 102 8.3E-11 T 12-10-2018 IPR009799 EthD domain VAPA_2c06970 77cd58b401eb19a2abd14bb62f48ab47 231 Pfam PF07110 EthD domain 13 97 1.5E-14 T 12-10-2018 IPR009799 EthD domain VAPA_2c06970 77cd58b401eb19a2abd14bb62f48ab47 231 Gene3D G3DSA:3.30.70.100 1 106 9.1E-18 T 12-10-2018 VAPA_2c06970 77cd58b401eb19a2abd14bb62f48ab47 231 Gene3D G3DSA:3.30.70.100 115 226 4.6E-35 T 12-10-2018 VAPA_2c06970 77cd58b401eb19a2abd14bb62f48ab47 231 Pfam PF09448 Methylmuconolactone methyl-isomerase 123 229 5.4E-23 T 12-10-2018 IPR018566 4-Methylmuconolactone methyl-isomerase VAPA_2c06970 77cd58b401eb19a2abd14bb62f48ab47 231 SUPERFAMILY SSF54909 1 110 1.34E-26 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel VAPA_2c06970 77cd58b401eb19a2abd14bb62f48ab47 231 SUPERFAMILY SSF54909 122 230 2.32E-27 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel VAPA_1c34900 f959ca309dff37795ff827edccb9d0d6 356 SMART SM00382 33 217 3.0E-9 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c34900 f959ca309dff37795ff827edccb9d0d6 356 SUPERFAMILY SSF50331 242 349 3.64E-16 T 12-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal VAPA_1c34900 f959ca309dff37795ff827edccb9d0d6 356 Gene3D G3DSA:3.40.50.300 7 228 1.0E-47 T 12-10-2018 VAPA_1c34900 f959ca309dff37795ff827edccb9d0d6 356 Gene3D G3DSA:2.40.50.140 284 341 3.2E-14 T 12-10-2018 VAPA_1c34900 f959ca309dff37795ff827edccb9d0d6 356 Pfam PF08402 TOBE domain 277 341 2.9E-10 T 12-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 VAPA_1c34900 f959ca309dff37795ff827edccb9d0d6 356 Pfam PF00005 ABC transporter 27 167 1.1E-20 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c34900 f959ca309dff37795ff827edccb9d0d6 356 Gene3D G3DSA:2.40.50.940 229 343 3.2E-14 T 12-10-2018 VAPA_1c34900 f959ca309dff37795ff827edccb9d0d6 356 SUPERFAMILY SSF52540 23 248 9.39E-60 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_2c09060 9ea3467e5c24ac6f7f69d9bffb1fe93e 85 Pfam PF02148 Zn-finger in ubiquitin-hydrolases and other protein 21 85 1.1E-12 T 12-10-2018 IPR001607 Zinc finger, UBP-type GO:0008270 VAPA_2c09060 9ea3467e5c24ac6f7f69d9bffb1fe93e 85 Gene3D G3DSA:3.30.40.10 1 85 2.1E-29 T 12-10-2018 IPR013083 Zinc finger, RING/FYVE/PHD-type VAPA_2c09060 9ea3467e5c24ac6f7f69d9bffb1fe93e 85 SUPERFAMILY SSF57850 2 84 8.12E-28 T 12-10-2018 VAPA_2c09050 3be772c64d96c7be8e24465c88941e59 560 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 187 202 1.4E-5 T 12-10-2018 VAPA_2c09050 3be772c64d96c7be8e24465c88941e59 560 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 22 44 1.4E-5 T 12-10-2018 VAPA_2c09050 3be772c64d96c7be8e24465c88941e59 560 SUPERFAMILY SSF54373 220 314 1.49E-36 T 12-10-2018 VAPA_2c09050 3be772c64d96c7be8e24465c88941e59 560 Pfam PF00890 FAD binding domain 22 62 4.5E-7 T 12-10-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 VAPA_2c09050 3be772c64d96c7be8e24465c88941e59 560 Gene3D G3DSA:3.30.70.20 461 555 1.8E-38 T 12-10-2018 VAPA_2c09050 3be772c64d96c7be8e24465c88941e59 560 SUPERFAMILY SSF51905 16 457 4.56E-56 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_2c09050 3be772c64d96c7be8e24465c88941e59 560 Gene3D G3DSA:3.50.50.60 21 393 1.3E-176 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_2c09050 3be772c64d96c7be8e24465c88941e59 560 Pfam PF05187 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S 456 557 9.8E-48 T 12-10-2018 VAPA_2c09050 3be772c64d96c7be8e24465c88941e59 560 SUPERFAMILY SSF54862 460 558 1.38E-27 T 12-10-2018 VAPA_2c09050 3be772c64d96c7be8e24465c88941e59 560 Gene3D G3DSA:3.30.9.90 88 460 1.3E-176 T 12-10-2018 VAPA_1c22700 6c7082b81ef0ea1637e5d75bfff9ebbb 442 Pfam PF01546 Peptidase family M20/M25/M40 101 427 5.8E-25 T 12-10-2018 IPR002933 Peptidase M20 GO:0016787 VAPA_1c22700 6c7082b81ef0ea1637e5d75bfff9ebbb 442 PIRSF PIRSF005962 31 436 2.3E-106 T 12-10-2018 IPR017439 Amidohydrolase GO:0016787 VAPA_1c22700 6c7082b81ef0ea1637e5d75bfff9ebbb 442 Gene3D G3DSA:3.30.70.360 222 338 1.7E-120 T 12-10-2018 VAPA_1c22700 6c7082b81ef0ea1637e5d75bfff9ebbb 442 Pfam PF07687 Peptidase dimerisation domain 226 324 3.8E-11 T 12-10-2018 IPR011650 Peptidase M20, dimerisation domain VAPA_1c22700 6c7082b81ef0ea1637e5d75bfff9ebbb 442 Gene3D G3DSA:3.40.630.10 43 417 1.7E-120 T 12-10-2018 VAPA_1c22700 6c7082b81ef0ea1637e5d75bfff9ebbb 442 SUPERFAMILY SSF53187 32 432 1.14E-75 T 12-10-2018 VAPA_1c22700 6c7082b81ef0ea1637e5d75bfff9ebbb 442 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 43 420 4.5E-94 T 12-10-2018 IPR017439 Amidohydrolase GO:0016787 VAPA_1c22700 6c7082b81ef0ea1637e5d75bfff9ebbb 442 SUPERFAMILY SSF55031 225 332 5.76E-26 T 12-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain VAPA_1c04120 8732b7afa8a058bd13df26c6934064af 412 Gene3D G3DSA:3.40.50.10540 13 405 3.6E-129 T 12-10-2018 IPR023606 CoA-transferase family III domain superfamily VAPA_1c04120 8732b7afa8a058bd13df26c6934064af 412 SUPERFAMILY SSF89796 12 411 7.06E-133 T 12-10-2018 IPR023606 CoA-transferase family III domain superfamily VAPA_1c04120 8732b7afa8a058bd13df26c6934064af 412 Gene3D G3DSA:3.30.1540.10 247 339 3.6E-129 T 12-10-2018 VAPA_1c04120 8732b7afa8a058bd13df26c6934064af 412 Pfam PF02515 CoA-transferase family III 14 388 8.9E-124 T 12-10-2018 IPR003673 CoA-transferase family III GO:0003824 VAPA_2c11650 1caba352f96d668f18355cd908d7ae4f 151 Pfam PF04828 Glutathione-dependent formaldehyde-activating enzyme 29 116 5.0E-14 T 12-10-2018 IPR006913 Glutathione-dependent formaldehyde-activating enzyme/centromere protein V GO:0016846 KEGG: 00680+4.4.1.22|MetaCyc: PWY-1801 VAPA_2c11650 1caba352f96d668f18355cd908d7ae4f 151 SUPERFAMILY SSF51316 5 135 8.47E-33 T 12-10-2018 IPR011057 Mss4-like superfamily VAPA_2c11650 1caba352f96d668f18355cd908d7ae4f 151 Gene3D G3DSA:3.90.1590.10 3 101 4.4E-11 T 12-10-2018 VAPA_1c40940 312024562ec672eafb87b7de4d5df9b2 259 TIGRFAM TIGR03234 OH-pyruv-isom: hydroxypyruvate isomerase 2 253 7.8E-122 T 12-10-2018 IPR017643 Hydroxypyruvate isomerase KEGG: 00630+5.3.1.22 VAPA_1c40940 312024562ec672eafb87b7de4d5df9b2 259 Pfam PF01261 Xylose isomerase-like TIM barrel 21 219 1.7E-36 T 12-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain VAPA_1c40940 312024562ec672eafb87b7de4d5df9b2 259 Gene3D G3DSA:3.20.20.150 1 259 1.2E-82 T 12-10-2018 VAPA_1c40940 312024562ec672eafb87b7de4d5df9b2 259 SUPERFAMILY SSF51658 1 255 1.19E-90 T 12-10-2018 IPR036237 Xylose isomerase-like superfamily VAPA_1c40940 312024562ec672eafb87b7de4d5df9b2 259 PIRSF PIRSF006241 1 259 8.7E-99 T 12-10-2018 IPR026040 Hydroxypyruvate isomerase-like VAPA_1c30230 efa6b4feaf8cc62b062af0a25eaad933 564 ProSitePatterns PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2. 470 481 - T 12-10-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 VAPA_1c30230 efa6b4feaf8cc62b062af0a25eaad933 564 Pfam PF00920 Dehydratase family 40 559 2.7E-204 T 12-10-2018 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 VAPA_1c30230 efa6b4feaf8cc62b062af0a25eaad933 564 TIGRFAM TIGR00110 ilvD: dihydroxy-acid dehydratase 23 562 1.9E-227 T 12-10-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 VAPA_1c30230 efa6b4feaf8cc62b062af0a25eaad933 564 SUPERFAMILY SSF52016 385 562 2.59E-55 T 12-10-2018 VAPA_1c30230 efa6b4feaf8cc62b062af0a25eaad933 564 Gene3D G3DSA:3.50.30.80 384 532 5.6E-50 T 12-10-2018 VAPA_1c30230 efa6b4feaf8cc62b062af0a25eaad933 564 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 128 138 - T 12-10-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 VAPA_1c30230 efa6b4feaf8cc62b062af0a25eaad933 564 SUPERFAMILY SSF143975 6 383 3.66E-137 T 12-10-2018 IPR037237 IlvD/EDD, N-terminal domain KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 VAPA_1c30230 efa6b4feaf8cc62b062af0a25eaad933 564 Hamap MF_00012 Dihydroxy-acid dehydratase [ilvD]. 10 562 44.157 T 12-10-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 VAPA_1c05120 a2850cdc26d097e1f070b34f51dbdb23 317 Gene3D G3DSA:3.30.1490.20 138 202 7.5E-104 T 12-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 VAPA_1c05120 a2850cdc26d097e1f070b34f51dbdb23 317 SUPERFAMILY SSF52440 3 123 1.7E-40 T 12-10-2018 IPR016185 Pre-ATP-grasp domain superfamily VAPA_1c05120 a2850cdc26d097e1f070b34f51dbdb23 317 Gene3D G3DSA:3.30.470.20 116 296 7.5E-104 T 12-10-2018 VAPA_1c05120 a2850cdc26d097e1f070b34f51dbdb23 317 SUPERFAMILY SSF56059 125 312 2.16E-54 T 12-10-2018 VAPA_1c05120 a2850cdc26d097e1f070b34f51dbdb23 317 Hamap MF_00162 Glutathione synthetase [gshB]. 1 317 156.938 T 12-10-2018 IPR006284 Glutathione synthetase, prokaryotic GO:0004363|GO:0005829|GO:0006750 KEGG: 00270+6.3.2.3|KEGG: 00480+6.3.2.3 VAPA_1c05120 a2850cdc26d097e1f070b34f51dbdb23 317 Gene3D G3DSA:3.40.50.20 7 115 7.5E-104 T 12-10-2018 VAPA_1c05120 a2850cdc26d097e1f070b34f51dbdb23 317 TIGRFAM TIGR01380 glut_syn: glutathione synthase 4 313 1.1E-123 T 12-10-2018 IPR006284 Glutathione synthetase, prokaryotic GO:0004363|GO:0005829|GO:0006750 KEGG: 00270+6.3.2.3|KEGG: 00480+6.3.2.3 VAPA_1c05120 a2850cdc26d097e1f070b34f51dbdb23 317 Pfam PF02951 Prokaryotic glutathione synthetase, N-terminal domain 3 121 9.1E-45 T 12-10-2018 IPR004215 Prokaryotic glutathione synthetase, N-terminal GO:0004363|GO:0006750 KEGG: 00270+6.3.2.3|KEGG: 00480+6.3.2.3 VAPA_1c05120 a2850cdc26d097e1f070b34f51dbdb23 317 Pfam PF02955 Prokaryotic glutathione synthetase, ATP-grasp domain 125 298 6.6E-70 T 12-10-2018 IPR004218 Prokaryotic glutathione synthetase, ATP-binding GO:0004363|GO:0005524|GO:0006750 KEGG: 00270+6.3.2.3|KEGG: 00480+6.3.2.3 VAPA_1c45790 73f0f61f5d62d801a6ad7a9318d51909 585 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 38 157 3.3E-14 T 12-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 VAPA_1c45790 73f0f61f5d62d801a6ad7a9318d51909 585 SUPERFAMILY SSF56645 38 274 1.3E-59 T 12-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 VAPA_1c45790 73f0f61f5d62d801a6ad7a9318d51909 585 SUPERFAMILY SSF47203 282 454 6.77E-46 T 12-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 VAPA_1c45790 73f0f61f5d62d801a6ad7a9318d51909 585 Gene3D G3DSA:2.40.110.10 161 280 2.8E-28 T 12-10-2018 VAPA_1c45790 73f0f61f5d62d801a6ad7a9318d51909 585 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 162 266 1.1E-19 T 12-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 VAPA_1c45790 73f0f61f5d62d801a6ad7a9318d51909 585 Gene3D G3DSA:1.20.140.10 281 452 2.2E-46 T 12-10-2018 VAPA_1c45790 73f0f61f5d62d801a6ad7a9318d51909 585 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 276 446 1.8E-18 T 12-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 VAPA_1c45790 73f0f61f5d62d801a6ad7a9318d51909 585 Gene3D G3DSA:1.10.540.10 31 159 3.1E-18 T 12-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 VAPA_2c00070 b12bdefb42850cf8214229022cc702dd 732 Pfam PF00425 chorismate binding enzyme 420 672 7.0E-92 T 12-10-2018 IPR015890 Chorismate-utilising enzyme, C-terminal VAPA_2c00070 b12bdefb42850cf8214229022cc702dd 732 SUPERFAMILY SSF56322 219 680 9.94E-130 T 12-10-2018 IPR005801 ADC synthase GO:0009058 VAPA_2c00070 b12bdefb42850cf8214229022cc702dd 732 TIGRFAM TIGR00566 trpG_papA: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase 3 185 1.3E-49 T 12-10-2018 IPR006221 Anthranilate synthase/para-aminobenzoate synthase like domain KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 VAPA_2c00070 b12bdefb42850cf8214229022cc702dd 732 Pfam PF04715 Anthranilate synthase component I, N terminal region 237 368 1.5E-18 T 12-10-2018 IPR006805 Anthranilate synthase component I, N-terminal GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 VAPA_2c00070 b12bdefb42850cf8214229022cc702dd 732 Gene3D G3DSA:3.60.120.10 210 685 2.1E-150 T 12-10-2018 IPR005801 ADC synthase GO:0009058 VAPA_2c00070 b12bdefb42850cf8214229022cc702dd 732 Pfam PF00117 Glutamine amidotransferase class-I 4 185 4.2E-43 T 12-10-2018 IPR017926 Glutamine amidotransferase VAPA_2c00070 b12bdefb42850cf8214229022cc702dd 732 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 77 93 2.3E-6 T 12-10-2018 VAPA_2c00070 b12bdefb42850cf8214229022cc702dd 732 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 46 60 2.3E-6 T 12-10-2018 VAPA_2c00070 b12bdefb42850cf8214229022cc702dd 732 PRINTS PR00096 Glutamine amidotransferase superfamily signature 77 88 1.1E-12 T 12-10-2018 VAPA_2c00070 b12bdefb42850cf8214229022cc702dd 732 PRINTS PR00096 Glutamine amidotransferase superfamily signature 49 58 1.1E-12 T 12-10-2018 VAPA_2c00070 b12bdefb42850cf8214229022cc702dd 732 PRINTS PR00096 Glutamine amidotransferase superfamily signature 165 178 1.1E-12 T 12-10-2018 VAPA_2c00070 b12bdefb42850cf8214229022cc702dd 732 SUPERFAMILY SSF52317 2 192 1.58E-49 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like VAPA_2c00070 b12bdefb42850cf8214229022cc702dd 732 PRINTS PR00097 Anthranilate synthase component II signature 165 178 1.0E-29 T 12-10-2018 VAPA_2c00070 b12bdefb42850cf8214229022cc702dd 732 PRINTS PR00097 Anthranilate synthase component II signature 102 110 1.0E-29 T 12-10-2018 VAPA_2c00070 b12bdefb42850cf8214229022cc702dd 732 PRINTS PR00097 Anthranilate synthase component II signature 3 17 1.0E-29 T 12-10-2018 VAPA_2c00070 b12bdefb42850cf8214229022cc702dd 732 PRINTS PR00097 Anthranilate synthase component II signature 49 58 1.0E-29 T 12-10-2018 VAPA_2c00070 b12bdefb42850cf8214229022cc702dd 732 PRINTS PR00097 Anthranilate synthase component II signature 77 88 1.0E-29 T 12-10-2018 VAPA_2c00070 b12bdefb42850cf8214229022cc702dd 732 PRINTS PR00097 Anthranilate synthase component II signature 122 134 1.0E-29 T 12-10-2018 VAPA_2c00070 b12bdefb42850cf8214229022cc702dd 732 TIGRFAM TIGR00553 pabB: aminodeoxychorismate synthase, component I 324 675 7.1E-111 T 12-10-2018 IPR005802 Para-aminobenzoate synthase, component I GO:0009396 KEGG: 00790+2.6.1.85|MetaCyc: PWY-6543 VAPA_2c00070 b12bdefb42850cf8214229022cc702dd 732 Gene3D G3DSA:3.40.50.880 1 187 4.0E-62 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like VAPA_1c38980 7b8238c23a7e52b6799d3c4398c280be 350 Gene3D G3DSA:3.90.78.10 236 350 6.5E-43 T 12-10-2018 IPR036635 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain superfamily GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 VAPA_1c38980 7b8238c23a7e52b6799d3c4398c280be 350 TIGRFAM TIGR00179 murB: UDP-N-acetylenolpyruvoylglucosamine reductase 9 346 3.8E-62 T 12-10-2018 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 VAPA_1c38980 7b8238c23a7e52b6799d3c4398c280be 350 Pfam PF02873 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain 223 350 2.3E-29 T 12-10-2018 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 VAPA_1c38980 7b8238c23a7e52b6799d3c4398c280be 350 Hamap MF_00037 UDP-N-acetylenolpyruvoylglucosamine reductase [murB]. 1 350 84.709 T 12-10-2018 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 VAPA_1c38980 7b8238c23a7e52b6799d3c4398c280be 350 Gene3D G3DSA:3.30.465.10 74 235 3.8E-52 T 12-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 VAPA_1c38980 7b8238c23a7e52b6799d3c4398c280be 350 SUPERFAMILY SSF56194 220 350 4.05E-42 T 12-10-2018 IPR036635 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain superfamily GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 VAPA_1c38980 7b8238c23a7e52b6799d3c4398c280be 350 SUPERFAMILY SSF56176 8 205 5.14E-40 T 12-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 VAPA_1c38980 7b8238c23a7e52b6799d3c4398c280be 350 Pfam PF01565 FAD binding domain 23 153 5.9E-21 T 12-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 VAPA_1c38980 7b8238c23a7e52b6799d3c4398c280be 350 Gene3D G3DSA:3.30.43.10 1 71 9.3E-20 T 12-10-2018 IPR016167 FAD-binding, type PCMH, subdomain 1 VAPA_1c35630 e812faa205e5dfaeda702b3a5bc626be 196 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 65 4.9E-12 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 VAPA_1c35630 e812faa205e5dfaeda702b3a5bc626be 196 SUPERFAMILY SSF48498 84 194 1.58E-16 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily VAPA_1c35630 e812faa205e5dfaeda702b3a5bc626be 196 SUPERFAMILY SSF46689 10 88 1.2E-16 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 VAPA_1c35630 e812faa205e5dfaeda702b3a5bc626be 196 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 20 33 3.1E-7 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 VAPA_1c35630 e812faa205e5dfaeda702b3a5bc626be 196 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 41 64 3.1E-7 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 VAPA_1c35630 e812faa205e5dfaeda702b3a5bc626be 196 Gene3D G3DSA:1.10.357.10 11 194 4.8E-41 T 12-10-2018 VAPA_2c05650 75200ffa0f8478006b0706cd17600b75 253 SUPERFAMILY SSF52096 3 253 1.01E-75 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily VAPA_2c05650 75200ffa0f8478006b0706cd17600b75 253 Pfam PF00378 Enoyl-CoA hydratase/isomerase 8 252 5.9E-54 T 12-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 VAPA_2c05650 75200ffa0f8478006b0706cd17600b75 253 Gene3D G3DSA:3.90.226.10 1 194 9.2E-60 T 12-10-2018 VAPA_2c05650 75200ffa0f8478006b0706cd17600b75 253 Gene3D G3DSA:1.10.12.10 196 253 5.4E-17 T 12-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal VAPA_2c12510 6af8200f6b563d7e16e47dbe463d70e6 302 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 6.6E-18 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_2c12510 6af8200f6b563d7e16e47dbe463d70e6 302 SUPERFAMILY SSF53850 90 291 3.88E-40 T 12-10-2018 VAPA_2c12510 6af8200f6b563d7e16e47dbe463d70e6 302 Pfam PF03466 LysR substrate binding domain 88 289 3.5E-38 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_2c12510 6af8200f6b563d7e16e47dbe463d70e6 302 SUPERFAMILY SSF46785 1 80 8.85E-19 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_2c12510 6af8200f6b563d7e16e47dbe463d70e6 302 Gene3D G3DSA:3.40.190.290 92 294 5.5E-38 T 12-10-2018 VAPA_2c12510 6af8200f6b563d7e16e47dbe463d70e6 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 3.0E-9 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_2c12510 6af8200f6b563d7e16e47dbe463d70e6 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 3.0E-9 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_2c12510 6af8200f6b563d7e16e47dbe463d70e6 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 3.0E-9 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_2c12510 6af8200f6b563d7e16e47dbe463d70e6 302 Gene3D G3DSA:1.10.10.10 1 91 1.1E-18 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c37300 98329eaf23fe28fdc4828baaa5a3b1e1 1035 Gene3D G3DSA:3.30.2090.10 712 800 3.9E-281 T 12-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains VAPA_1c37300 98329eaf23fe28fdc4828baaa5a3b1e1 1035 SUPERFAMILY SSF82693 668 848 2.88E-7 T 12-10-2018 VAPA_1c37300 98329eaf23fe28fdc4828baaa5a3b1e1 1035 SUPERFAMILY SSF82693 136 333 9.94E-20 T 12-10-2018 VAPA_1c37300 98329eaf23fe28fdc4828baaa5a3b1e1 1035 Gene3D G3DSA:3.30.2090.10 179 269 3.9E-281 T 12-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains VAPA_1c37300 98329eaf23fe28fdc4828baaa5a3b1e1 1035 Gene3D G3DSA:3.30.70.1320 133 335 3.9E-281 T 12-10-2018 VAPA_1c37300 98329eaf23fe28fdc4828baaa5a3b1e1 1035 Gene3D G3DSA:3.30.70.1440 660 858 3.9E-281 T 12-10-2018 VAPA_1c37300 98329eaf23fe28fdc4828baaa5a3b1e1 1035 Pfam PF00873 AcrB/AcrD/AcrF family 6 1019 4.6E-299 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 VAPA_1c37300 98329eaf23fe28fdc4828baaa5a3b1e1 1035 SUPERFAMILY SSF82693 564 658 4.19E-10 T 12-10-2018 VAPA_1c37300 98329eaf23fe28fdc4828baaa5a3b1e1 1035 Gene3D G3DSA:1.20.1640.10 512 1016 3.9E-281 T 12-10-2018 VAPA_1c37300 98329eaf23fe28fdc4828baaa5a3b1e1 1035 Gene3D G3DSA:1.20.1640.10 10 511 3.9E-281 T 12-10-2018 VAPA_1c37300 98329eaf23fe28fdc4828baaa5a3b1e1 1035 SUPERFAMILY SSF82714 716 797 8.89E-16 T 12-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains VAPA_1c37300 98329eaf23fe28fdc4828baaa5a3b1e1 1035 SUPERFAMILY SSF82866 299 499 3.66E-46 T 12-10-2018 VAPA_1c37300 98329eaf23fe28fdc4828baaa5a3b1e1 1035 PRINTS PR00702 Acriflavin resistance protein family signature 366 387 9.7E-68 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 VAPA_1c37300 98329eaf23fe28fdc4828baaa5a3b1e1 1035 PRINTS PR00702 Acriflavin resistance protein family signature 38 56 9.7E-68 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 VAPA_1c37300 98329eaf23fe28fdc4828baaa5a3b1e1 1035 PRINTS PR00702 Acriflavin resistance protein family signature 551 568 9.7E-68 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 VAPA_1c37300 98329eaf23fe28fdc4828baaa5a3b1e1 1035 PRINTS PR00702 Acriflavin resistance protein family signature 339 362 9.7E-68 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 VAPA_1c37300 98329eaf23fe28fdc4828baaa5a3b1e1 1035 PRINTS PR00702 Acriflavin resistance protein family signature 10 34 9.7E-68 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 VAPA_1c37300 98329eaf23fe28fdc4828baaa5a3b1e1 1035 PRINTS PR00702 Acriflavin resistance protein family signature 472 495 9.7E-68 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 VAPA_1c37300 98329eaf23fe28fdc4828baaa5a3b1e1 1035 PRINTS PR00702 Acriflavin resistance protein family signature 394 418 9.7E-68 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 VAPA_1c37300 98329eaf23fe28fdc4828baaa5a3b1e1 1035 PRINTS PR00702 Acriflavin resistance protein family signature 447 470 9.7E-68 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 VAPA_1c37300 98329eaf23fe28fdc4828baaa5a3b1e1 1035 SUPERFAMILY SSF82866 826 1020 4.58E-43 T 12-10-2018 VAPA_1c37300 98329eaf23fe28fdc4828baaa5a3b1e1 1035 SUPERFAMILY SSF82693 40 130 2.88E-22 T 12-10-2018 VAPA_1c37300 98329eaf23fe28fdc4828baaa5a3b1e1 1035 Gene3D G3DSA:3.30.70.1430 40 808 3.9E-281 T 12-10-2018 VAPA_1c37300 98329eaf23fe28fdc4828baaa5a3b1e1 1035 Gene3D G3DSA:3.30.70.1430 566 659 3.9E-281 T 12-10-2018 VAPA_1c37300 98329eaf23fe28fdc4828baaa5a3b1e1 1035 SUPERFAMILY SSF82714 183 266 7.85E-17 T 12-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains VAPA_1c03970 bde20624dd02af0e870f4c31cb8001ef 388 SUPERFAMILY SSF55031 179 286 1.5E-19 T 12-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain VAPA_1c03970 bde20624dd02af0e870f4c31cb8001ef 388 Pfam PF07687 Peptidase dimerisation domain 175 286 7.5E-20 T 12-10-2018 IPR011650 Peptidase M20, dimerisation domain VAPA_1c03970 bde20624dd02af0e870f4c31cb8001ef 388 SUPERFAMILY SSF53187 7 382 5.14E-55 T 12-10-2018 VAPA_1c03970 bde20624dd02af0e870f4c31cb8001ef 388 TIGRFAM TIGR01892 AcOrn-deacetyl: acetylornithine deacetylase (ArgE) 14 381 4.7E-104 T 12-10-2018 IPR010169 Acetylornithine deacetylase ArgE GO:0005737|GO:0006526|GO:0008777 KEGG: 00220+3.5.1.16|MetaCyc: PWY-5154 VAPA_1c03970 bde20624dd02af0e870f4c31cb8001ef 388 Pfam PF01546 Peptidase family M20/M25/M40 72 382 3.3E-31 T 12-10-2018 IPR002933 Peptidase M20 GO:0016787 VAPA_1c03970 bde20624dd02af0e870f4c31cb8001ef 388 Gene3D G3DSA:3.40.630.10 16 371 1.0E-96 T 12-10-2018 VAPA_1c03970 bde20624dd02af0e870f4c31cb8001ef 388 Gene3D G3DSA:3.30.70.360 179 295 1.0E-96 T 12-10-2018 VAPA_1c39870 951225905302d49f182ccad85d90baf3 274 Gene3D G3DSA:3.40.225.10 27 271 6.2E-77 T 12-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily VAPA_1c39870 951225905302d49f182ccad85d90baf3 274 SMART SM01007 45 225 8.3E-54 T 12-10-2018 IPR001303 Class II aldolase/adducin N-terminal VAPA_1c39870 951225905302d49f182ccad85d90baf3 274 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 46 225 1.4E-47 T 12-10-2018 IPR001303 Class II aldolase/adducin N-terminal VAPA_1c39870 951225905302d49f182ccad85d90baf3 274 SUPERFAMILY SSF53639 37 251 1.04E-64 T 12-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily VAPA_1c11750 94fc8cfad404f54030b94590a99753cb 96 Hamap MF_00580 10 kDa chaperonin [groS]. 2 95 26.308 T 12-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 VAPA_1c11750 94fc8cfad404f54030b94590a99753cb 96 Gene3D G3DSA:2.30.33.40 1 96 6.5E-37 T 12-10-2018 IPR037124 GroES chaperonin superfamily GO:0005737|GO:0006457 VAPA_1c11750 94fc8cfad404f54030b94590a99753cb 96 SUPERFAMILY SSF50129 1 95 2.09E-33 T 12-10-2018 IPR011032 GroES-like superfamily VAPA_1c11750 94fc8cfad404f54030b94590a99753cb 96 Pfam PF00166 Chaperonin 10 Kd subunit 2 94 7.0E-34 T 12-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 VAPA_1c11750 94fc8cfad404f54030b94590a99753cb 96 PRINTS PR00297 10kDa chaperonin signature 3 18 4.2E-32 T 12-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 VAPA_1c11750 94fc8cfad404f54030b94590a99753cb 96 PRINTS PR00297 10kDa chaperonin signature 25 46 4.2E-32 T 12-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 VAPA_1c11750 94fc8cfad404f54030b94590a99753cb 96 PRINTS PR00297 10kDa chaperonin signature 81 94 4.2E-32 T 12-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 VAPA_1c11750 94fc8cfad404f54030b94590a99753cb 96 PRINTS PR00297 10kDa chaperonin signature 60 72 4.2E-32 T 12-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 VAPA_1c11750 94fc8cfad404f54030b94590a99753cb 96 SMART SM00883 2 94 4.1E-55 T 12-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 VAPA_1c11750 94fc8cfad404f54030b94590a99753cb 96 ProSitePatterns PS00681 Chaperonins cpn10 signature. 3 27 - T 12-10-2018 IPR018369 Chaperonin GroES, conserved site GO:0005524|GO:0006457 VAPA_2c06130 2057fa81b9d438120dd787b6bf28ac9a 341 SMART SM00382 52 248 6.1E-16 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_2c06130 2057fa81b9d438120dd787b6bf28ac9a 341 Gene3D G3DSA:3.40.50.300 31 339 3.6E-92 T 12-10-2018 VAPA_2c06130 2057fa81b9d438120dd787b6bf28ac9a 341 ProSitePatterns PS00211 ABC transporters family signature. 171 185 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_2c06130 2057fa81b9d438120dd787b6bf28ac9a 341 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 250 314 7.5E-17 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 VAPA_2c06130 2057fa81b9d438120dd787b6bf28ac9a 341 SUPERFAMILY SSF52540 36 269 2.72E-62 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_2c06130 2057fa81b9d438120dd787b6bf28ac9a 341 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 248 334 5.5E-27 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 VAPA_2c06130 2057fa81b9d438120dd787b6bf28ac9a 341 Pfam PF00005 ABC transporter 44 198 2.2E-26 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c19570 438c94e37e4df8cdd389dff824e1a392 218 SUPERFAMILY SSF48498 92 217 3.34E-37 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily VAPA_1c19570 438c94e37e4df8cdd389dff824e1a392 218 Gene3D G3DSA:1.10.357.10 22 218 2.7E-70 T 12-10-2018 VAPA_1c19570 438c94e37e4df8cdd389dff824e1a392 218 Pfam PF00440 Bacterial regulatory proteins, tetR family 26 72 1.4E-16 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 VAPA_1c19570 438c94e37e4df8cdd389dff824e1a392 218 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 26 39 3.8E-9 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 VAPA_1c19570 438c94e37e4df8cdd389dff824e1a392 218 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 47 70 3.8E-9 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 VAPA_1c19570 438c94e37e4df8cdd389dff824e1a392 218 Pfam PF08362 YcdC-like protein, C-terminal region 78 214 2.2E-4 T 12-10-2018 IPR013573 Transcription regulator YcdC, C-terminal GO:0045892 VAPA_1c19570 438c94e37e4df8cdd389dff824e1a392 218 SUPERFAMILY SSF46689 14 97 1.18E-20 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 VAPA_1c02210 3ad95c04f08aa678817da5f500bd48fe 244 SUPERFAMILY SSF52540 6 241 1.67E-55 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c02210 3ad95c04f08aa678817da5f500bd48fe 244 SMART SM00382 32 220 7.1E-5 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c02210 3ad95c04f08aa678817da5f500bd48fe 244 Gene3D G3DSA:3.40.50.300 3 244 1.5E-58 T 12-10-2018 VAPA_1c02210 3ad95c04f08aa678817da5f500bd48fe 244 Pfam PF00005 ABC transporter 24 172 2.6E-28 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c02210 3ad95c04f08aa678817da5f500bd48fe 244 ProSitePatterns PS00211 ABC transporters family signature. 145 159 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_1c43330 47b3dcd4a11e24712924a0d625754ad0 153 TIGRFAM TIGR02480 fliN: flagellar motor switch protein FliN 69 143 1.9E-31 T 12-10-2018 IPR012826 Flagellar motor switch FliN GO:0006935|GO:0009288|GO:0016020|GO:0071973 VAPA_1c43330 47b3dcd4a11e24712924a0d625754ad0 153 PRINTS PR00956 Flagellar motor switch protein FliN signature 88 104 4.0E-28 T 12-10-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 VAPA_1c43330 47b3dcd4a11e24712924a0d625754ad0 153 PRINTS PR00956 Flagellar motor switch protein FliN signature 71 87 4.0E-28 T 12-10-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 VAPA_1c43330 47b3dcd4a11e24712924a0d625754ad0 153 PRINTS PR00956 Flagellar motor switch protein FliN signature 117 132 4.0E-28 T 12-10-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 VAPA_1c43330 47b3dcd4a11e24712924a0d625754ad0 153 PRINTS PR00956 Flagellar motor switch protein FliN signature 104 117 4.0E-28 T 12-10-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 VAPA_1c43330 47b3dcd4a11e24712924a0d625754ad0 153 Gene3D G3DSA:2.30.330.10 61 152 1.1E-32 T 12-10-2018 IPR036429 SpoA-like superfamily VAPA_1c43330 47b3dcd4a11e24712924a0d625754ad0 153 Pfam PF01052 Type III flagellar switch regulator (C-ring) FliN C-term 70 141 3.9E-25 T 12-10-2018 IPR001543 Surface presentation of antigen (SpoA) VAPA_1c43330 47b3dcd4a11e24712924a0d625754ad0 153 SUPERFAMILY SSF101801 69 150 3.66E-25 T 12-10-2018 IPR036429 SpoA-like superfamily VAPA_1c11710 8874116daface820cfb5d86a653a8d85 322 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 243 256 - T 12-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 VAPA_1c11710 8874116daface820cfb5d86a653a8d85 322 SUPERFAMILY SSF53613 1 305 3.9E-67 T 12-10-2018 IPR029056 Ribokinase-like VAPA_1c11710 8874116daface820cfb5d86a653a8d85 322 Pfam PF00294 pfkB family carbohydrate kinase 3 301 2.0E-47 T 12-10-2018 IPR011611 Carbohydrate kinase PfkB VAPA_1c11710 8874116daface820cfb5d86a653a8d85 322 Gene3D G3DSA:3.40.1190.20 1 320 6.7E-82 T 12-10-2018 IPR029056 Ribokinase-like VAPA_1c11710 8874116daface820cfb5d86a653a8d85 322 PRINTS PR00990 Ribokinase signature 23 42 6.2E-6 T 12-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 VAPA_1c11710 8874116daface820cfb5d86a653a8d85 322 PRINTS PR00990 Ribokinase signature 174 189 6.2E-6 T 12-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 VAPA_1c11710 8874116daface820cfb5d86a653a8d85 322 PRINTS PR00990 Ribokinase signature 213 224 6.2E-6 T 12-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 VAPA_2c00480 9e6b25569e6be72ef1fa383caecd7ca4 225 SMART SM00895 85 209 5.3E-20 T 12-10-2018 IPR011711 GntR, C-terminal VAPA_2c00480 9e6b25569e6be72ef1fa383caecd7ca4 225 SMART SM00345 17 75 1.6E-11 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_2c00480 9e6b25569e6be72ef1fa383caecd7ca4 225 Gene3D G3DSA:1.20.120.530 79 221 3.6E-29 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal VAPA_2c00480 9e6b25569e6be72ef1fa383caecd7ca4 225 SUPERFAMILY SSF48008 81 217 1.44E-26 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal VAPA_2c00480 9e6b25569e6be72ef1fa383caecd7ca4 225 Gene3D G3DSA:1.10.10.10 2 77 3.2E-19 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_2c00480 9e6b25569e6be72ef1fa383caecd7ca4 225 Pfam PF07729 FCD domain 85 208 1.5E-25 T 12-10-2018 IPR011711 GntR, C-terminal VAPA_2c00480 9e6b25569e6be72ef1fa383caecd7ca4 225 SUPERFAMILY SSF46785 9 79 3.11E-18 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_2c00480 9e6b25569e6be72ef1fa383caecd7ca4 225 Pfam PF00392 Bacterial regulatory proteins, gntR family 14 75 4.5E-15 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_2c00660 859ea3d72383e6c2aefa5ded299bd8be 414 Pfam PF01266 FAD dependent oxidoreductase 2 398 8.5E-64 T 12-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 VAPA_2c00660 859ea3d72383e6c2aefa5ded299bd8be 414 SUPERFAMILY SSF54373 270 360 8.5E-15 T 12-10-2018 VAPA_2c00660 859ea3d72383e6c2aefa5ded299bd8be 414 Gene3D G3DSA:3.30.9.10 134 362 1.0E-53 T 12-10-2018 VAPA_2c00660 859ea3d72383e6c2aefa5ded299bd8be 414 Gene3D G3DSA:3.50.50.60 97 404 1.0E-53 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_2c00660 859ea3d72383e6c2aefa5ded299bd8be 414 Gene3D G3DSA:3.50.50.60 1 85 4.5E-14 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_2c00660 859ea3d72383e6c2aefa5ded299bd8be 414 SUPERFAMILY SSF51905 1 410 2.07E-48 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c21700 d5c21ec7dcaac0d8e2f4950af082b39c 1871 SUPERFAMILY SSF51120 1717 1860 9.94E-19 T 12-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal VAPA_1c21700 d5c21ec7dcaac0d8e2f4950af082b39c 1871 Gene3D G3DSA:2.150.10.10 1619 1865 3.5E-36 T 12-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal VAPA_1c21700 d5c21ec7dcaac0d8e2f4950af082b39c 1871 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 1754 1772 - T 12-10-2018 IPR018511 Hemolysin-type calcium-binding conserved site VAPA_1c21700 d5c21ec7dcaac0d8e2f4950af082b39c 1871 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 1745 1763 - T 12-10-2018 IPR018511 Hemolysin-type calcium-binding conserved site VAPA_1c21700 d5c21ec7dcaac0d8e2f4950af082b39c 1871 PRINTS PR00313 NodO calcium binding signature 1749 1757 1.2E-7 T 12-10-2018 VAPA_1c21700 d5c21ec7dcaac0d8e2f4950af082b39c 1871 PRINTS PR00313 NodO calcium binding signature 1767 1776 1.2E-7 T 12-10-2018 VAPA_1c21700 d5c21ec7dcaac0d8e2f4950af082b39c 1871 PRINTS PR00313 NodO calcium binding signature 1737 1748 1.2E-7 T 12-10-2018 VAPA_1c21700 d5c21ec7dcaac0d8e2f4950af082b39c 1871 PRINTS PR00313 NodO calcium binding signature 1758 1766 1.2E-7 T 12-10-2018 VAPA_1c21700 d5c21ec7dcaac0d8e2f4950af082b39c 1871 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 1740 1756 3.0E-4 T 12-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 VAPA_1c21700 d5c21ec7dcaac0d8e2f4950af082b39c 1871 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 1757 1773 0.09 T 12-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 VAPA_1c40300 c1f2343373c626fc21465fce4174cc3e 2498 SUPERFAMILY SSF52777 13 189 5.89E-33 T 12-10-2018 VAPA_1c40300 c1f2343373c626fc21465fce4174cc3e 2498 TIGRFAM TIGR01746 Thioester-redct: thioester reductase domain 2134 2445 2.3E-81 T 12-10-2018 IPR010080 Thioester reductase-like domain VAPA_1c40300 c1f2343373c626fc21465fce4174cc3e 2498 Gene3D G3DSA:3.30.559.10 13 212 1.3E-53 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 VAPA_1c40300 c1f2343373c626fc21465fce4174cc3e 2498 Pfam PF00668 Condensation domain 10 449 1.1E-65 T 12-10-2018 IPR001242 Condensation domain VAPA_1c40300 c1f2343373c626fc21465fce4174cc3e 2498 Pfam PF00668 Condensation domain 1063 1514 2.5E-88 T 12-10-2018 IPR001242 Condensation domain VAPA_1c40300 c1f2343373c626fc21465fce4174cc3e 2498 Gene3D G3DSA:3.30.559.30 223 441 1.7E-58 T 12-10-2018 VAPA_1c40300 c1f2343373c626fc21465fce4174cc3e 2498 SUPERFAMILY SSF56801 428 992 2.88E-169 T 12-10-2018 VAPA_1c40300 c1f2343373c626fc21465fce4174cc3e 2498 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 492 895 1.7E-138 T 12-10-2018 IPR010071 Amino acid adenylation domain VAPA_1c40300 c1f2343373c626fc21465fce4174cc3e 2498 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1554 1949 3.0E-127 T 12-10-2018 IPR010071 Amino acid adenylation domain VAPA_1c40300 c1f2343373c626fc21465fce4174cc3e 2498 Gene3D G3DSA:1.10.1200.10 967 1051 2.3E-28 T 12-10-2018 IPR036736 ACP-like superfamily VAPA_1c40300 c1f2343373c626fc21465fce4174cc3e 2498 Gene3D G3DSA:1.10.1200.10 2019 2102 4.2E-25 T 12-10-2018 IPR036736 ACP-like superfamily VAPA_1c40300 c1f2343373c626fc21465fce4174cc3e 2498 Pfam PF00501 AMP-binding enzyme 1534 1925 3.3E-90 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 VAPA_1c40300 c1f2343373c626fc21465fce4174cc3e 2498 Pfam PF00501 AMP-binding enzyme 469 871 2.2E-98 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 VAPA_1c40300 c1f2343373c626fc21465fce4174cc3e 2498 Gene3D G3DSA:3.30.559.30 1246 1499 5.2E-145 T 12-10-2018 VAPA_1c40300 c1f2343373c626fc21465fce4174cc3e 2498 SUPERFAMILY SSF52777 1065 1237 3.56E-47 T 12-10-2018 VAPA_1c40300 c1f2343373c626fc21465fce4174cc3e 2498 Pfam PF07993 Male sterility protein 2136 2371 4.4E-54 T 12-10-2018 IPR013120 Male sterility, NAD-binding Reactome: R-HSA-8848584 VAPA_1c40300 c1f2343373c626fc21465fce4174cc3e 2498 SUPERFAMILY SSF52777 1251 1497 2.33E-57 T 12-10-2018 VAPA_1c40300 c1f2343373c626fc21465fce4174cc3e 2498 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2056 2071 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site VAPA_1c40300 c1f2343373c626fc21465fce4174cc3e 2498 Pfam PF00550 Phosphopantetheine attachment site 982 1044 7.6E-16 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain VAPA_1c40300 c1f2343373c626fc21465fce4174cc3e 2498 Pfam PF00550 Phosphopantetheine attachment site 2035 2097 1.2E-10 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain VAPA_1c40300 c1f2343373c626fc21465fce4174cc3e 2498 Gene3D G3DSA:3.30.559.10 1064 1437 5.2E-145 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 VAPA_1c40300 c1f2343373c626fc21465fce4174cc3e 2498 SUPERFAMILY SSF51735 2128 2403 1.24E-41 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c40300 c1f2343373c626fc21465fce4174cc3e 2498 SUPERFAMILY SSF56801 1493 2044 3.53E-152 T 12-10-2018 VAPA_1c40300 c1f2343373c626fc21465fce4174cc3e 2498 Pfam PF13193 AMP-binding enzyme C-terminal domain 1933 2006 2.2E-16 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain VAPA_1c40300 c1f2343373c626fc21465fce4174cc3e 2498 Pfam PF13193 AMP-binding enzyme C-terminal domain 879 954 2.9E-16 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain VAPA_1c40300 c1f2343373c626fc21465fce4174cc3e 2498 SUPERFAMILY SSF52777 195 456 8.89E-42 T 12-10-2018 VAPA_1c40300 c1f2343373c626fc21465fce4174cc3e 2498 SUPERFAMILY SSF47336 971 1045 5.76E-21 T 12-10-2018 IPR036736 ACP-like superfamily VAPA_1c40300 c1f2343373c626fc21465fce4174cc3e 2498 Gene3D G3DSA:3.40.50.720 2107 2484 7.4E-90 T 12-10-2018 VAPA_1c40300 c1f2343373c626fc21465fce4174cc3e 2498 Gene3D G3DSA:3.40.50.12780 1521 1919 4.0E-129 T 12-10-2018 VAPA_1c40300 c1f2343373c626fc21465fce4174cc3e 2498 SMART SM00823 Phosphopantetheine attachment site 2032 2101 7.1E-4 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 VAPA_1c40300 c1f2343373c626fc21465fce4174cc3e 2498 SMART SM00823 Phosphopantetheine attachment site 982 1048 8.6E-4 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 VAPA_1c40300 c1f2343373c626fc21465fce4174cc3e 2498 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1678 1689 - T 12-10-2018 IPR020845 AMP-binding, conserved site VAPA_1c40300 c1f2343373c626fc21465fce4174cc3e 2498 Gene3D G3DSA:3.40.50.12780 459 863 7.5E-143 T 12-10-2018 VAPA_1c40300 c1f2343373c626fc21465fce4174cc3e 2498 SUPERFAMILY SSF47336 2024 2098 2.09E-19 T 12-10-2018 IPR036736 ACP-like superfamily VAPA_1c40300 c1f2343373c626fc21465fce4174cc3e 2498 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1003 1018 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site VAPA_1c40300 c1f2343373c626fc21465fce4174cc3e 2498 ProSitePatterns PS00455 Putative AMP-binding domain signature. 611 622 - T 12-10-2018 IPR020845 AMP-binding, conserved site VAPA_1c40300 c1f2343373c626fc21465fce4174cc3e 2498 Gene3D G3DSA:3.30.300.30 865 966 7.6E-38 T 12-10-2018 VAPA_1c40300 c1f2343373c626fc21465fce4174cc3e 2498 Gene3D G3DSA:3.30.300.30 1920 2018 6.2E-37 T 12-10-2018 VAPA_1c47800 4c70770ecbe7d21eec49c6341d6fb093 318 Gene3D G3DSA:3.40.50.2300 141 277 2.0E-82 T 12-10-2018 VAPA_1c47800 4c70770ecbe7d21eec49c6341d6fb093 318 SUPERFAMILY SSF53822 6 318 2.36E-69 T 12-10-2018 IPR028082 Periplasmic binding protein-like I VAPA_1c47800 4c70770ecbe7d21eec49c6341d6fb093 318 Gene3D G3DSA:3.40.50.2300 38 292 2.0E-82 T 12-10-2018 VAPA_1c47800 4c70770ecbe7d21eec49c6341d6fb093 318 Pfam PF13407 Periplasmic binding protein domain 33 296 7.3E-48 T 12-10-2018 IPR025997 Periplasmic binding protein VAPA_1c18060 df4f61bdee534803cb152caa9edd2255 330 PIRSF PIRSF017082 1 330 4.7E-73 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c18060 df4f61bdee534803cb152caa9edd2255 330 Gene3D G3DSA:3.40.190.10 129 255 8.4E-106 T 12-10-2018 VAPA_1c18060 df4f61bdee534803cb152caa9edd2255 330 Gene3D G3DSA:3.40.190.150 33 320 8.4E-106 T 12-10-2018 VAPA_1c18060 df4f61bdee534803cb152caa9edd2255 330 SUPERFAMILY SSF53850 115 298 3.99E-18 T 12-10-2018 VAPA_1c18060 df4f61bdee534803cb152caa9edd2255 330 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 51 326 1.0E-85 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c41060 48b7176200b50a7035abbd1712555021 342 Pfam PF09084 NMT1/THI5 like 44 256 8.8E-39 T 12-10-2018 IPR015168 SsuA/THI5-like VAPA_1c41060 48b7176200b50a7035abbd1712555021 342 Gene3D G3DSA:3.40.190.10 114 219 6.5E-60 T 12-10-2018 VAPA_1c41060 48b7176200b50a7035abbd1712555021 342 Gene3D G3DSA:3.40.190.10 33 309 6.5E-60 T 12-10-2018 VAPA_1c41060 48b7176200b50a7035abbd1712555021 342 SUPERFAMILY SSF53850 37 263 1.88E-27 T 12-10-2018 VAPA_1c36910 01467799588954179021798d461f552a 336 PIRSF PIRSF017082 6 335 1.3E-66 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c36910 01467799588954179021798d461f552a 336 SUPERFAMILY SSF53850 130 295 2.17E-7 T 12-10-2018 VAPA_1c36910 01467799588954179021798d461f552a 336 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 63 332 5.2E-70 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c36910 01467799588954179021798d461f552a 336 Gene3D G3DSA:3.40.190.150 43 326 3.4E-91 T 12-10-2018 VAPA_1c36910 01467799588954179021798d461f552a 336 Gene3D G3DSA:3.40.190.10 140 261 3.4E-91 T 12-10-2018 VAPA_1c06870 a5448ae3ccfd4682c043a410ded0ca6c 237 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_1c06870 a5448ae3ccfd4682c043a410ded0ca6c 237 SMART SM00382 29 214 7.3E-8 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c06870 a5448ae3ccfd4682c043a410ded0ca6c 237 Pfam PF00005 ABC transporter 22 165 1.4E-27 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c06870 a5448ae3ccfd4682c043a410ded0ca6c 237 Gene3D G3DSA:3.40.50.300 2 237 6.3E-61 T 12-10-2018 VAPA_1c06870 a5448ae3ccfd4682c043a410ded0ca6c 237 SUPERFAMILY SSF52540 4 235 3.07E-58 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c53510 01bcd94212653e524e332c6a8b75f44f 360 SUPERFAMILY SSF110997 285 349 6.02E-10 T 12-10-2018 IPR036680 Sporulation-like domain superfamily GO:0042834 VAPA_1c53510 01bcd94212653e524e332c6a8b75f44f 360 Pfam PF05036 Sporulation related domain 283 357 4.0E-12 T 12-10-2018 IPR007730 Sporulation-like domain GO:0042834 VAPA_1c53510 01bcd94212653e524e332c6a8b75f44f 360 Pfam PF03330 Lytic transglycolase 77 163 3.1E-25 T 12-10-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain VAPA_1c53510 01bcd94212653e524e332c6a8b75f44f 360 TIGRFAM TIGR00413 rlpA: rare lipoprotein A 78 169 7.4E-40 T 12-10-2018 IPR012997 Rare lipoprotein A VAPA_1c53510 01bcd94212653e524e332c6a8b75f44f 360 Gene3D G3DSA:2.40.40.10 75 168 3.0E-35 T 12-10-2018 IPR036908 RlpA-like domain superfamily VAPA_1c53510 01bcd94212653e524e332c6a8b75f44f 360 Gene3D G3DSA:3.30.70.1070 278 355 2.8E-6 T 12-10-2018 IPR036680 Sporulation-like domain superfamily GO:0042834 VAPA_1c53510 01bcd94212653e524e332c6a8b75f44f 360 Hamap MF_02071 Endolytic peptidoglycan transglycosylase RlpA [rlpA]. 2 167 23.44 T 12-10-2018 IPR034718 Endolytic peptidoglycan transglycosylase RlpA GO:0016829 VAPA_1c53510 01bcd94212653e524e332c6a8b75f44f 360 SUPERFAMILY SSF50685 77 166 2.27E-9 T 12-10-2018 IPR036908 RlpA-like domain superfamily VAPA_1c54430 4285f1ddf119ef828aa6d129b9ef4dbc 265 Gene3D G3DSA:1.10.3720.10 51 261 1.6E-22 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c54430 4285f1ddf119ef828aa6d129b9ef4dbc 265 SUPERFAMILY SSF161098 56 242 4.19E-30 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c54430 4285f1ddf119ef828aa6d129b9ef4dbc 265 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 79 260 1.1E-28 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 VAPA_2c11370 4ff855f5ba420cb0b77b9d951d45ed9a 408 Pfam PF13433 Periplasmic binding protein domain 33 380 8.0E-81 T 12-10-2018 VAPA_2c11370 4ff855f5ba420cb0b77b9d951d45ed9a 408 SUPERFAMILY SSF53822 31 378 1.59E-88 T 12-10-2018 IPR028082 Periplasmic binding protein-like I VAPA_2c11370 4ff855f5ba420cb0b77b9d951d45ed9a 408 Gene3D G3DSA:3.40.50.2300 147 377 1.4E-112 T 12-10-2018 VAPA_2c11370 4ff855f5ba420cb0b77b9d951d45ed9a 408 Gene3D G3DSA:3.40.50.2300 34 362 1.4E-112 T 12-10-2018 VAPA_1c11910 d545665a01843180fbbb6d37afc12361 221 SUPERFAMILY SSF46626 133 219 1.12E-22 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 VAPA_1c11910 d545665a01843180fbbb6d37afc12361 221 PIRSF PIRSF000005 1 221 1.6E-60 T 12-10-2018 IPR024167 Cytochrome c4-like GO:0005506|GO:0009055|GO:0020037|GO:0042597 VAPA_1c11910 d545665a01843180fbbb6d37afc12361 221 Gene3D G3DSA:1.10.760.10 128 221 1.1E-26 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 VAPA_1c11910 d545665a01843180fbbb6d37afc12361 221 Gene3D G3DSA:1.10.760.10 50 123 3.2E-24 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 VAPA_1c11910 d545665a01843180fbbb6d37afc12361 221 Pfam PF00034 Cytochrome c 145 219 2.1E-8 T 12-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 VAPA_1c11910 d545665a01843180fbbb6d37afc12361 221 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 42 119 1.8E-7 T 12-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 VAPA_1c11910 d545665a01843180fbbb6d37afc12361 221 SUPERFAMILY SSF46626 30 121 2.81E-20 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 VAPA_1c11910 d545665a01843180fbbb6d37afc12361 221 PRINTS PR00605 Class IC cytochrome C signature 55 66 2.3E-5 T 12-10-2018 IPR008168 Cytochrome c, class IC GO:0005506|GO:0009055 VAPA_1c11910 d545665a01843180fbbb6d37afc12361 221 PRINTS PR00605 Class IC cytochrome C signature 195 217 2.3E-5 T 12-10-2018 IPR008168 Cytochrome c, class IC GO:0005506|GO:0009055 VAPA_2c00140 883bed1635209df08af3a81940a2b88f 270 Gene3D G3DSA:1.10.12.10 214 270 1.0E-10 T 12-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal VAPA_2c00140 883bed1635209df08af3a81940a2b88f 270 Pfam PF00378 Enoyl-CoA hydratase/isomerase 14 269 9.5E-55 T 12-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 VAPA_2c00140 883bed1635209df08af3a81940a2b88f 270 SUPERFAMILY SSF52096 1 270 1.3E-76 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily VAPA_2c00140 883bed1635209df08af3a81940a2b88f 270 Gene3D G3DSA:3.90.226.10 1 211 3.8E-65 T 12-10-2018 VAPA_1c13270 c57245e5c1130312e0218571f90d5baf 286 Hamap MF_00905 3',5'-cyclic adenosine monophosphate phosphodiesterase CpdA [cpdA]. 10 269 36.615 T 12-10-2018 IPR026575 3,5-cyclic adenosine monophosphate phosphodiesterase CpdA GO:0004115 KEGG: 00230+3.1.4.53 VAPA_1c13270 c57245e5c1130312e0218571f90d5baf 286 Pfam PF00149 Calcineurin-like phosphoesterase 13 210 2.8E-20 T 12-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 VAPA_1c13270 c57245e5c1130312e0218571f90d5baf 286 Gene3D G3DSA:3.60.21.40 12 253 4.1E-88 T 12-10-2018 VAPA_1c13270 c57245e5c1130312e0218571f90d5baf 286 SUPERFAMILY SSF56300 12 259 2.37E-55 T 12-10-2018 VAPA_1c13270 c57245e5c1130312e0218571f90d5baf 286 Gene3D G3DSA:3.30.750.180 117 244 4.1E-88 T 12-10-2018 VAPA_1c37200 15a0fd6f4b0f919842514bf06b73494d 322 Gene3D G3DSA:3.40.190.10 124 247 1.1E-106 T 12-10-2018 VAPA_1c37200 15a0fd6f4b0f919842514bf06b73494d 322 Gene3D G3DSA:3.40.190.150 26 312 1.1E-106 T 12-10-2018 VAPA_1c37200 15a0fd6f4b0f919842514bf06b73494d 322 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 46 318 1.8E-82 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c37200 15a0fd6f4b0f919842514bf06b73494d 322 PIRSF PIRSF017082 1 321 2.6E-75 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c37200 15a0fd6f4b0f919842514bf06b73494d 322 SUPERFAMILY SSF53850 108 290 4.34E-12 T 12-10-2018 VAPA_1c37810 5bda98af8cfd966b8bf49587f02b6604 174 Pfam PF00565 Staphylococcal nuclease homologue 52 151 6.1E-21 T 12-10-2018 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold Reactome: R-HSA-6802952 VAPA_1c37810 5bda98af8cfd966b8bf49587f02b6604 174 Gene3D G3DSA:2.40.50.90 25 163 8.2E-27 T 12-10-2018 IPR035437 SNase-like, OB-fold superfamily VAPA_1c37810 5bda98af8cfd966b8bf49587f02b6604 174 SUPERFAMILY SSF50199 19 158 1.83E-33 T 12-10-2018 VAPA_1c37810 5bda98af8cfd966b8bf49587f02b6604 174 SMART SM00318 23 151 9.3E-31 T 12-10-2018 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold Reactome: R-HSA-6802952 VAPA_1c24040 bc813b75355fdcefa43bcb30c2b061aa 799 TIGRFAM TIGR03904 SAM_YgiQ: uncharacterized radical SAM protein YgiQ 33 691 3.0E-253 T 12-10-2018 IPR022946 Uncharacterised protein family UPF0313 VAPA_1c24040 bc813b75355fdcefa43bcb30c2b061aa 799 Hamap MF_01251 UPF0313 protein YgiQ [ygiQ]. 33 693 48.999 T 12-10-2018 IPR022946 Uncharacterised protein family UPF0313 VAPA_1c24040 bc813b75355fdcefa43bcb30c2b061aa 799 SUPERFAMILY SSF102114 422 664 5.89E-12 T 12-10-2018 VAPA_1c24040 bc813b75355fdcefa43bcb30c2b061aa 799 Pfam PF04055 Radical SAM superfamily 427 630 3.3E-19 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 VAPA_1c24040 bc813b75355fdcefa43bcb30c2b061aa 799 Pfam PF11842 Domain of unknown function (DUF3362) 641 776 1.2E-58 T 12-10-2018 IPR024560 Uncharacterised protein family UPF0313, C-terminal VAPA_1c24040 bc813b75355fdcefa43bcb30c2b061aa 799 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 427 447 - T 12-10-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 VAPA_1c24040 bc813b75355fdcefa43bcb30c2b061aa 799 Pfam PF08497 Radical SAM N-terminal 33 426 2.5E-141 T 12-10-2018 IPR013704 Uncharacterised protein family UPF0313, N-terminal VAPA_1c24040 bc813b75355fdcefa43bcb30c2b061aa 799 Gene3D G3DSA:3.80.30.20 422 688 2.4E-15 T 12-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe VAPA_1c24040 bc813b75355fdcefa43bcb30c2b061aa 799 SMART SM00729 423 676 1.0E-6 T 12-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 VAPA_1c54110 2202b8c03264ad6cdb0709d681b053b2 332 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 54 326 2.5E-81 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c54110 2202b8c03264ad6cdb0709d681b053b2 332 Gene3D G3DSA:3.40.190.150 34 321 7.2E-108 T 12-10-2018 VAPA_1c54110 2202b8c03264ad6cdb0709d681b053b2 332 Gene3D G3DSA:3.40.190.10 131 257 7.2E-108 T 12-10-2018 VAPA_1c54110 2202b8c03264ad6cdb0709d681b053b2 332 PIRSF PIRSF017082 1 331 3.0E-71 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c54110 2202b8c03264ad6cdb0709d681b053b2 332 SUPERFAMILY SSF53850 80 294 5.43E-10 T 12-10-2018 VAPA_1c13950 a10571f194de968cba3c6f5de70d46d8 416 Pfam PF00817 impB/mucB/samB family 17 195 6.2E-46 T 12-10-2018 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 VAPA_1c13950 a10571f194de968cba3c6f5de70d46d8 416 Hamap MF_01113 DNA polymerase IV [dinB]. 11 395 32.134 T 12-10-2018 IPR022880 DNA polymerase IV GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 VAPA_1c13950 a10571f194de968cba3c6f5de70d46d8 416 Pfam PF11798 IMS family HHH motif 208 238 5.3E-7 T 12-10-2018 IPR024728 DNA polymerase type-Y, HhH motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 VAPA_1c13950 a10571f194de968cba3c6f5de70d46d8 416 Gene3D G3DSA:1.10.150.20 209 278 1.6E-19 T 12-10-2018 VAPA_1c13950 a10571f194de968cba3c6f5de70d46d8 416 Gene3D G3DSA:3.30.1490.100 284 389 4.2E-23 T 12-10-2018 IPR036775 DNA polymerase, Y-family, little finger domain superfamily GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 VAPA_1c13950 a10571f194de968cba3c6f5de70d46d8 416 Gene3D G3DSA:2.30.40.20 22 111 1.3E-20 T 12-10-2018 VAPA_1c13950 a10571f194de968cba3c6f5de70d46d8 416 SUPERFAMILY SSF100879 284 387 2.94E-24 T 12-10-2018 IPR036775 DNA polymerase, Y-family, little finger domain superfamily GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 VAPA_1c13950 a10571f194de968cba3c6f5de70d46d8 416 SUPERFAMILY SSF56672 9 276 1.51E-75 T 12-10-2018 VAPA_1c13950 a10571f194de968cba3c6f5de70d46d8 416 Gene3D G3DSA:3.30.70.270 112 205 1.4E-25 T 12-10-2018 VAPA_1c13950 a10571f194de968cba3c6f5de70d46d8 416 Pfam PF11799 impB/mucB/samB family C-terminal domain 277 388 8.9E-17 T 12-10-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 VAPA_1c52910 670f6f356c6bc5ad7957c46b879ba69b 482 Pfam PF00224 Pyruvate kinase, barrel domain 10 347 4.8E-117 T 12-10-2018 IPR015793 Pyruvate kinase, barrel GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 VAPA_1c52910 670f6f356c6bc5ad7957c46b879ba69b 482 SUPERFAMILY SSF52935 332 480 2.75E-38 T 12-10-2018 IPR036918 Pyruvate kinase, C-terminal domain superfamily KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 VAPA_1c52910 670f6f356c6bc5ad7957c46b879ba69b 482 SUPERFAMILY SSF51621 4 347 3.49E-90 T 12-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 VAPA_1c52910 670f6f356c6bc5ad7957c46b879ba69b 482 Pfam PF02887 Pyruvate kinase, alpha/beta domain 367 478 7.9E-29 T 12-10-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 VAPA_1c52910 670f6f356c6bc5ad7957c46b879ba69b 482 Gene3D G3DSA:3.20.20.60 10 344 5.1E-162 T 12-10-2018 VAPA_1c52910 670f6f356c6bc5ad7957c46b879ba69b 482 TIGRFAM TIGR01064 pyruv_kin: pyruvate kinase 10 478 1.6E-157 T 12-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 VAPA_1c52910 670f6f356c6bc5ad7957c46b879ba69b 482 PRINTS PR01050 Pyruvate kinase family signature 322 338 1.8E-59 T 12-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 VAPA_1c52910 670f6f356c6bc5ad7957c46b879ba69b 482 PRINTS PR01050 Pyruvate kinase family signature 192 206 1.8E-59 T 12-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 VAPA_1c52910 670f6f356c6bc5ad7957c46b879ba69b 482 PRINTS PR01050 Pyruvate kinase family signature 66 82 1.8E-59 T 12-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 VAPA_1c52910 670f6f356c6bc5ad7957c46b879ba69b 482 PRINTS PR01050 Pyruvate kinase family signature 226 252 1.8E-59 T 12-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 VAPA_1c52910 670f6f356c6bc5ad7957c46b879ba69b 482 PRINTS PR01050 Pyruvate kinase family signature 253 277 1.8E-59 T 12-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 VAPA_1c52910 670f6f356c6bc5ad7957c46b879ba69b 482 PRINTS PR01050 Pyruvate kinase family signature 278 302 1.8E-59 T 12-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 VAPA_1c52910 670f6f356c6bc5ad7957c46b879ba69b 482 PRINTS PR01050 Pyruvate kinase family signature 303 321 1.8E-59 T 12-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 VAPA_1c52910 670f6f356c6bc5ad7957c46b879ba69b 482 Gene3D G3DSA:3.40.1380.20 345 477 5.1E-162 T 12-10-2018 IPR036918 Pyruvate kinase, C-terminal domain superfamily KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 VAPA_1c52910 670f6f356c6bc5ad7957c46b879ba69b 482 Gene3D G3DSA:2.40.33.10 77 174 5.1E-162 T 12-10-2018 IPR015806 Pyruvate kinase, insert domain superfamily GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 VAPA_1c52910 670f6f356c6bc5ad7957c46b879ba69b 482 SUPERFAMILY SSF50800 77 170 7.33E-25 T 12-10-2018 IPR011037 Pyruvate kinase-like, insert domain superfamily VAPA_2c10830 f51582bb974f158b73a4a10aee0984bf 191 SUPERFAMILY SSF69118 1 176 2.22E-31 T 12-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 VAPA_2c10830 f51582bb974f158b73a4a10aee0984bf 191 Pfam PF02627 Carboxymuconolactone decarboxylase family 42 111 1.8E-6 T 12-10-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 VAPA_2c10830 f51582bb974f158b73a4a10aee0984bf 191 Gene3D G3DSA:1.20.1290.10 16 178 2.4E-31 T 12-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 VAPA_1c39370 9bf2c9d941bc2272e8eb8550a3790dbf 607 TIGRFAM TIGR03457 sulphoacet_xsc: sulfoacetaldehyde acetyltransferase 19 603 0.0 T 12-10-2018 IPR017820 Sulphoacetaldehyde acetyltransferase GO:0000287|GO:0005737|GO:0019529|GO:0030976|GO:0050487 KEGG: 00430+2.3.3.15|MetaCyc: PWY-1281|MetaCyc: PWY-6637 VAPA_1c39370 9bf2c9d941bc2272e8eb8550a3790dbf 607 Gene3D G3DSA:3.40.50.1220 200 383 8.8E-46 T 12-10-2018 VAPA_1c39370 9bf2c9d941bc2272e8eb8550a3790dbf 607 Gene3D G3DSA:3.40.50.970 14 193 3.6E-48 T 12-10-2018 VAPA_1c39370 9bf2c9d941bc2272e8eb8550a3790dbf 607 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 20 186 2.0E-43 T 12-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 VAPA_1c39370 9bf2c9d941bc2272e8eb8550a3790dbf 607 SUPERFAMILY SSF52467 197 381 1.5E-41 T 12-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily VAPA_1c39370 9bf2c9d941bc2272e8eb8550a3790dbf 607 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 205 342 3.6E-32 T 12-10-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 VAPA_1c39370 9bf2c9d941bc2272e8eb8550a3790dbf 607 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 427 578 5.5E-35 T 12-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 VAPA_1c39370 9bf2c9d941bc2272e8eb8550a3790dbf 607 Gene3D G3DSA:3.40.50.970 397 590 5.9E-52 T 12-10-2018 VAPA_1c39370 9bf2c9d941bc2272e8eb8550a3790dbf 607 SUPERFAMILY SSF52518 18 194 1.52E-44 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold VAPA_1c39370 9bf2c9d941bc2272e8eb8550a3790dbf 607 SUPERFAMILY SSF52518 405 602 4.57E-49 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold VAPA_1c23510 65176abcd8f1071dddeca4411e73b05f 958 Pfam PF00676 Dehydrogenase E1 component 225 510 1.8E-42 T 12-10-2018 IPR001017 Dehydrogenase, E1 component GO:0016624 Reactome: R-HSA-389661 VAPA_1c23510 65176abcd8f1071dddeca4411e73b05f 958 Pfam PF02779 Transketolase, pyrimidine binding domain 605 802 3.0E-63 T 12-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain VAPA_1c23510 65176abcd8f1071dddeca4411e73b05f 958 Pfam PF16078 2-oxoglutarate dehydrogenase N-terminus 17 54 1.0E-16 T 12-10-2018 IPR032106 2-oxoglutarate dehydrogenase E1 component, N-terminal domain KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 VAPA_1c23510 65176abcd8f1071dddeca4411e73b05f 958 TIGRFAM TIGR00239 2oxo_dh_E1: oxoglutarate dehydrogenase (succinyl-transferring), E1 component 19 946 0.0 T 12-10-2018 IPR011603 2-oxoglutarate dehydrogenase E1 component GO:0004591|GO:0006099|GO:0030976|GO:0055114 KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 VAPA_1c23510 65176abcd8f1071dddeca4411e73b05f 958 PIRSF PIRSF000157 4 950 0.0 T 12-10-2018 IPR011603 2-oxoglutarate dehydrogenase E1 component GO:0004591|GO:0006099|GO:0030976|GO:0055114 KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 VAPA_1c23510 65176abcd8f1071dddeca4411e73b05f 958 SMART SM00861 605 802 1.8E-62 T 12-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain VAPA_1c23510 65176abcd8f1071dddeca4411e73b05f 958 Gene3D G3DSA:3.40.50.970 178 533 1.2E-138 T 12-10-2018 VAPA_1c23510 65176abcd8f1071dddeca4411e73b05f 958 Pfam PF16870 2-oxoglutarate dehydrogenase C-terminal 807 948 1.6E-54 T 12-10-2018 IPR031717 Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 VAPA_1c23510 65176abcd8f1071dddeca4411e73b05f 958 Gene3D G3DSA:3.40.50.11610 739 944 3.7E-170 T 12-10-2018 VAPA_1c23510 65176abcd8f1071dddeca4411e73b05f 958 SUPERFAMILY SSF52518 587 809 7.07E-48 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold VAPA_1c23510 65176abcd8f1071dddeca4411e73b05f 958 Gene3D G3DSA:3.40.50.12470 569 818 3.7E-170 T 12-10-2018 VAPA_1c23510 65176abcd8f1071dddeca4411e73b05f 958 SUPERFAMILY SSF52518 132 557 3.68E-83 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold VAPA_1c23510 65176abcd8f1071dddeca4411e73b05f 958 Gene3D G3DSA:1.10.287.1150 96 177 4.5E-24 T 12-10-2018 VAPA_1c10110 ac98c51914399de413fd49c2ed59a2be 565 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 446 541 1.5E-11 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase VAPA_1c10110 ac98c51914399de413fd49c2ed59a2be 565 SMART SM00387 445 560 9.5E-20 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase VAPA_1c10110 ac98c51914399de413fd49c2ed59a2be 565 Gene3D G3DSA:3.30.565.10 408 562 3.4E-21 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_1c10110 ac98c51914399de413fd49c2ed59a2be 565 SUPERFAMILY SSF55785 212 321 1.59E-6 T 12-10-2018 IPR035965 PAS domain superfamily VAPA_1c10110 ac98c51914399de413fd49c2ed59a2be 565 SMART SM00388 336 401 1.7E-16 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 VAPA_1c10110 ac98c51914399de413fd49c2ed59a2be 565 Gene3D G3DSA:3.30.450.20 207 318 9.8E-6 T 12-10-2018 VAPA_1c10110 ac98c51914399de413fd49c2ed59a2be 565 Gene3D G3DSA:1.10.287.130 325 401 7.8E-20 T 12-10-2018 VAPA_1c10110 ac98c51914399de413fd49c2ed59a2be 565 SUPERFAMILY SSF47384 331 400 2.94E-15 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 VAPA_1c10110 ac98c51914399de413fd49c2ed59a2be 565 Pfam PF00512 His Kinase A (phospho-acceptor) domain 336 399 3.6E-13 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 VAPA_1c10110 ac98c51914399de413fd49c2ed59a2be 565 SUPERFAMILY SSF55874 419 540 1.24E-21 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_1c26100 f87b41847a06d244b3982976298fdff4 551 TIGRFAM TIGR01132 pgm: phosphoglucomutase, alpha-D-glucose phosphate-specific 5 548 5.0E-259 T 12-10-2018 IPR005852 Phosphoglucomutase, alpha-D-glucose specific GO:0004614|GO:0005975 KEGG: 00010+5.4.2.2|KEGG: 00030+5.4.2.2|KEGG: 00052+5.4.2.2|KEGG: 00230+5.4.2.2|KEGG: 00500+5.4.2.2|KEGG: 00520+5.4.2.2|KEGG: 00521+5.4.2.2|MetaCyc: PWY-2723|MetaCyc: PWY-3801|MetaCyc: PWY-5384|MetaCyc: PWY-5661|MetaCyc: PWY-5940|MetaCyc: PWY-5941|MetaCyc: PWY-622|MetaCyc: PWY-6317|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-6981|MetaCyc: PWY-7238|MetaCyc: PWY-7343|MetaCyc: PWY-7900|MetaCyc: PWY-7902 VAPA_1c26100 f87b41847a06d244b3982976298fdff4 551 Gene3D G3DSA:3.40.120.10 19 223 1.2E-69 T 12-10-2018 VAPA_1c26100 f87b41847a06d244b3982976298fdff4 551 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 143 152 - T 12-10-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 VAPA_1c26100 f87b41847a06d244b3982976298fdff4 551 Gene3D G3DSA:3.40.120.10 323 447 4.9E-34 T 12-10-2018 VAPA_1c26100 f87b41847a06d244b3982976298fdff4 551 SUPERFAMILY SSF55957 443 548 5.06E-17 T 12-10-2018 IPR036900 Alpha-D-phosphohexomutase, C-terminal domain superfamily GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 VAPA_1c26100 f87b41847a06d244b3982976298fdff4 551 SUPERFAMILY SSF53738 28 231 4.32E-46 T 12-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 VAPA_1c26100 f87b41847a06d244b3982976298fdff4 551 SUPERFAMILY SSF53738 310 449 3.18E-30 T 12-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 VAPA_1c26100 f87b41847a06d244b3982976298fdff4 551 SUPERFAMILY SSF53738 211 321 7.06E-12 T 12-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 VAPA_1c26100 f87b41847a06d244b3982976298fdff4 551 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 495 540 1.9E-7 T 12-10-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 VAPA_1c26100 f87b41847a06d244b3982976298fdff4 551 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 42 181 5.3E-34 T 12-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 VAPA_1c26100 f87b41847a06d244b3982976298fdff4 551 Gene3D G3DSA:3.30.310.50 448 550 2.8E-33 T 12-10-2018 VAPA_1c26100 f87b41847a06d244b3982976298fdff4 551 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 326 442 4.2E-28 T 12-10-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 VAPA_1c26100 f87b41847a06d244b3982976298fdff4 551 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 213 318 1.4E-8 T 12-10-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 VAPA_1c26100 f87b41847a06d244b3982976298fdff4 551 Gene3D G3DSA:3.40.120.10 224 322 4.0E-38 T 12-10-2018 VAPA_1c45980 292b327308f4c6448b1bed055a28ef2d 315 PIRSF PIRSF001439 4 314 8.9E-76 T 12-10-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 VAPA_1c45980 292b327308f4c6448b1bed055a28ef2d 315 Gene3D G3DSA:3.40.50.720 122 294 1.6E-89 T 12-10-2018 VAPA_1c45980 292b327308f4c6448b1bed055a28ef2d 315 Pfam PF02423 Ornithine cyclodeaminase/mu-crystallin family 13 312 4.6E-71 T 12-10-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 VAPA_1c45980 292b327308f4c6448b1bed055a28ef2d 315 Gene3D G3DSA:3.30.1780.10 13 311 1.6E-89 T 12-10-2018 IPR023401 Ornithine cyclodeaminase, N-terminal Reactome: R-HSA-71064 VAPA_1c45980 292b327308f4c6448b1bed055a28ef2d 315 SUPERFAMILY SSF51735 1 311 6.58E-91 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c24800 4b633c1c39c6151f589659aae78cabca 438 SUPERFAMILY SSF63882 26 197 6.8E-47 T 12-10-2018 IPR036135 MoeA, N-terminal and linker domain superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 VAPA_1c24800 4b633c1c39c6151f589659aae78cabca 438 SUPERFAMILY SSF63867 359 437 1.7E-22 T 12-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 VAPA_1c24800 4b633c1c39c6151f589659aae78cabca 438 Gene3D G3DSA:3.90.105.10 40 195 1.6E-131 T 12-10-2018 VAPA_1c24800 4b633c1c39c6151f589659aae78cabca 438 Gene3D G3DSA:2.170.190.11 64 162 1.6E-131 T 12-10-2018 VAPA_1c24800 4b633c1c39c6151f589659aae78cabca 438 SUPERFAMILY SSF53218 198 353 1.96E-42 T 12-10-2018 IPR036425 MoaB/Mog-like domain superfamily VAPA_1c24800 4b633c1c39c6151f589659aae78cabca 438 Gene3D G3DSA:2.40.340.10 361 431 1.6E-131 T 12-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 VAPA_1c24800 4b633c1c39c6151f589659aae78cabca 438 Pfam PF00994 Probable molybdopterin binding domain 203 346 2.0E-30 T 12-10-2018 IPR001453 MoaB/Mog domain VAPA_1c24800 4b633c1c39c6151f589659aae78cabca 438 Pfam PF03454 MoeA C-terminal region (domain IV) 364 436 1.6E-19 T 12-10-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 VAPA_1c24800 4b633c1c39c6151f589659aae78cabca 438 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 198 344 1.3E-31 T 12-10-2018 IPR001453 MoaB/Mog domain VAPA_1c24800 4b633c1c39c6151f589659aae78cabca 438 SMART SM00852 201 348 1.5E-45 T 12-10-2018 IPR001453 MoaB/Mog domain VAPA_1c24800 4b633c1c39c6151f589659aae78cabca 438 Pfam PF03453 MoeA N-terminal region (domain I and II) 29 188 1.7E-40 T 12-10-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 VAPA_1c24800 4b633c1c39c6151f589659aae78cabca 438 Gene3D G3DSA:3.40.980.10 196 360 1.6E-131 T 12-10-2018 IPR036425 MoaB/Mog-like domain superfamily VAPA_1c04800 c0dc90430e114804c780be7f4c7c02bf 708 Gene3D G3DSA:3.40.50.300 30 313 1.0E-75 T 12-10-2018 VAPA_1c04800 c0dc90430e114804c780be7f4c7c02bf 708 SUPERFAMILY SSF52540 27 648 1.63E-121 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c04800 c0dc90430e114804c780be7f4c7c02bf 708 Pfam PF13245 AAA domain 49 298 1.2E-30 T 12-10-2018 VAPA_1c04800 c0dc90430e114804c780be7f4c7c02bf 708 Pfam PF13361 UvrD-like helicase C-terminal domain 320 473 1.2E-19 T 12-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 VAPA_1c04800 c0dc90430e114804c780be7f4c7c02bf 708 Pfam PF13361 UvrD-like helicase C-terminal domain 582 640 5.3E-18 T 12-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 VAPA_1c04800 c0dc90430e114804c780be7f4c7c02bf 708 Gene3D G3DSA:1.10.10.160 146 231 1.0E-75 T 12-10-2018 IPR013986 DExx box DNA helicase domain superfamily VAPA_1c04800 c0dc90430e114804c780be7f4c7c02bf 708 Gene3D G3DSA:1.10.486.10 424 568 4.1E-65 T 12-10-2018 VAPA_1c04800 c0dc90430e114804c780be7f4c7c02bf 708 Gene3D G3DSA:3.40.50.300 323 648 4.1E-65 T 12-10-2018 VAPA_1c03070 cb17c90ba21f7dfe15b67b23a7170177 314 SUPERFAMILY SSF53850 92 301 1.81E-24 T 12-10-2018 VAPA_1c03070 cb17c90ba21f7dfe15b67b23a7170177 314 Pfam PF03466 LysR substrate binding domain 88 297 1.2E-21 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_1c03070 cb17c90ba21f7dfe15b67b23a7170177 314 SUPERFAMILY SSF46785 1 110 3.18E-23 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c03070 cb17c90ba21f7dfe15b67b23a7170177 314 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 4.5E-21 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c03070 cb17c90ba21f7dfe15b67b23a7170177 314 Gene3D G3DSA:3.40.190.10 93 285 1.4E-38 T 12-10-2018 VAPA_1c03070 cb17c90ba21f7dfe15b67b23a7170177 314 Gene3D G3DSA:1.10.10.10 1 88 9.2E-27 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c03070 cb17c90ba21f7dfe15b67b23a7170177 314 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 2.9E-7 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c03070 cb17c90ba21f7dfe15b67b23a7170177 314 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 2.9E-7 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c03070 cb17c90ba21f7dfe15b67b23a7170177 314 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 2.9E-7 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c03070 cb17c90ba21f7dfe15b67b23a7170177 314 Gene3D G3DSA:3.40.190.10 166 270 1.4E-38 T 12-10-2018 VAPA_1c03880 338a6e67d45d858276b60c0742393f90 250 PRINTS PR00721 Stomatin signature 172 193 3.2E-61 T 12-10-2018 IPR001972 Stomatin family GO:0016020 VAPA_1c03880 338a6e67d45d858276b60c0742393f90 250 PRINTS PR00721 Stomatin signature 109 126 3.2E-61 T 12-10-2018 IPR001972 Stomatin family GO:0016020 VAPA_1c03880 338a6e67d45d858276b60c0742393f90 250 PRINTS PR00721 Stomatin signature 153 171 3.2E-61 T 12-10-2018 IPR001972 Stomatin family GO:0016020 VAPA_1c03880 338a6e67d45d858276b60c0742393f90 250 PRINTS PR00721 Stomatin signature 197 220 3.2E-61 T 12-10-2018 IPR001972 Stomatin family GO:0016020 VAPA_1c03880 338a6e67d45d858276b60c0742393f90 250 PRINTS PR00721 Stomatin signature 129 152 3.2E-61 T 12-10-2018 IPR001972 Stomatin family GO:0016020 VAPA_1c03880 338a6e67d45d858276b60c0742393f90 250 PRINTS PR00721 Stomatin signature 74 95 3.2E-61 T 12-10-2018 IPR001972 Stomatin family GO:0016020 VAPA_1c03880 338a6e67d45d858276b60c0742393f90 250 PRINTS PR00721 Stomatin signature 27 49 3.2E-61 T 12-10-2018 IPR001972 Stomatin family GO:0016020 VAPA_1c03880 338a6e67d45d858276b60c0742393f90 250 SMART SM00244 20 177 8.8E-56 T 12-10-2018 IPR001107 Band 7 domain VAPA_1c03880 338a6e67d45d858276b60c0742393f90 250 SUPERFAMILY SSF117892 51 184 1.1E-41 T 12-10-2018 IPR036013 Band 7/SPFH domain superfamily VAPA_1c03880 338a6e67d45d858276b60c0742393f90 250 Gene3D G3DSA:3.30.479.30 48 179 8.4E-46 T 12-10-2018 VAPA_1c03880 338a6e67d45d858276b60c0742393f90 250 Pfam PF01145 SPFH domain / Band 7 family 26 193 3.7E-33 T 12-10-2018 IPR001107 Band 7 domain VAPA_1c49150 7af794e8babf31f79a71706a86d78be5 276 Pfam PF00005 ABC transporter 38 178 8.0E-30 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c49150 7af794e8babf31f79a71706a86d78be5 276 SUPERFAMILY SSF52540 22 249 1.09E-64 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c49150 7af794e8babf31f79a71706a86d78be5 276 Gene3D G3DSA:3.40.50.300 15 245 1.1E-59 T 12-10-2018 VAPA_1c49150 7af794e8babf31f79a71706a86d78be5 276 ProSitePatterns PS00211 ABC transporters family signature. 151 165 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_1c49150 7af794e8babf31f79a71706a86d78be5 276 SMART SM00382 45 229 8.4E-14 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c21900 a0f5e608333f8072f7b132ecab855d40 134 Gene3D G3DSA:3.30.429.10 1 61 4.9E-5 T 12-10-2018 IPR014347 Tautomerase/MIF superfamily VAPA_1c21900 a0f5e608333f8072f7b132ecab855d40 134 Gene3D G3DSA:3.30.429.10 67 124 9.6E-7 T 12-10-2018 IPR014347 Tautomerase/MIF superfamily VAPA_1c21900 a0f5e608333f8072f7b132ecab855d40 134 SUPERFAMILY SSF55331 1 122 1.98E-11 T 12-10-2018 IPR014347 Tautomerase/MIF superfamily VAPA_1c06800 8ea756e5a90d05c1163258f951d57dbc 1014 SUPERFAMILY SSF82866 781 1006 1.96E-44 T 12-10-2018 VAPA_1c06800 8ea756e5a90d05c1163258f951d57dbc 1014 Gene3D G3DSA:3.30.70.1320 134 324 5.2E-269 T 12-10-2018 VAPA_1c06800 8ea756e5a90d05c1163258f951d57dbc 1014 Gene3D G3DSA:1.20.1640.10 502 998 5.2E-269 T 12-10-2018 VAPA_1c06800 8ea756e5a90d05c1163258f951d57dbc 1014 SUPERFAMILY SSF82693 548 644 1.01E-11 T 12-10-2018 VAPA_1c06800 8ea756e5a90d05c1163258f951d57dbc 1014 Gene3D G3DSA:1.20.1640.10 10 501 5.2E-269 T 12-10-2018 VAPA_1c06800 8ea756e5a90d05c1163258f951d57dbc 1014 Gene3D G3DSA:3.30.2090.10 178 268 5.2E-269 T 12-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains VAPA_1c06800 8ea756e5a90d05c1163258f951d57dbc 1014 SUPERFAMILY SSF82693 41 130 3.66E-17 T 12-10-2018 VAPA_1c06800 8ea756e5a90d05c1163258f951d57dbc 1014 Gene3D G3DSA:3.30.2090.10 693 783 5.2E-269 T 12-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains VAPA_1c06800 8ea756e5a90d05c1163258f951d57dbc 1014 PRINTS PR00702 Acriflavin resistance protein family signature 38 56 1.4E-50 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 VAPA_1c06800 8ea756e5a90d05c1163258f951d57dbc 1014 PRINTS PR00702 Acriflavin resistance protein family signature 328 351 1.4E-50 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 VAPA_1c06800 8ea756e5a90d05c1163258f951d57dbc 1014 PRINTS PR00702 Acriflavin resistance protein family signature 383 407 1.4E-50 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 VAPA_1c06800 8ea756e5a90d05c1163258f951d57dbc 1014 PRINTS PR00702 Acriflavin resistance protein family signature 461 484 1.4E-50 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 VAPA_1c06800 8ea756e5a90d05c1163258f951d57dbc 1014 PRINTS PR00702 Acriflavin resistance protein family signature 355 376 1.4E-50 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 VAPA_1c06800 8ea756e5a90d05c1163258f951d57dbc 1014 PRINTS PR00702 Acriflavin resistance protein family signature 436 459 1.4E-50 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 VAPA_1c06800 8ea756e5a90d05c1163258f951d57dbc 1014 PRINTS PR00702 Acriflavin resistance protein family signature 534 551 1.4E-50 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 VAPA_1c06800 8ea756e5a90d05c1163258f951d57dbc 1014 PRINTS PR00702 Acriflavin resistance protein family signature 10 34 1.4E-50 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 VAPA_1c06800 8ea756e5a90d05c1163258f951d57dbc 1014 Gene3D G3DSA:3.30.70.1430 40 791 5.2E-269 T 12-10-2018 VAPA_1c06800 8ea756e5a90d05c1163258f951d57dbc 1014 SUPERFAMILY SSF82866 291 489 1.96E-43 T 12-10-2018 VAPA_1c06800 8ea756e5a90d05c1163258f951d57dbc 1014 SUPERFAMILY SSF82714 182 263 1.1E-10 T 12-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains VAPA_1c06800 8ea756e5a90d05c1163258f951d57dbc 1014 Gene3D G3DSA:3.30.70.1430 549 645 5.2E-269 T 12-10-2018 VAPA_1c06800 8ea756e5a90d05c1163258f951d57dbc 1014 Gene3D G3DSA:3.30.70.1440 646 840 5.2E-269 T 12-10-2018 VAPA_1c06800 8ea756e5a90d05c1163258f951d57dbc 1014 SUPERFAMILY SSF82714 694 780 1.7E-10 T 12-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains VAPA_1c06800 8ea756e5a90d05c1163258f951d57dbc 1014 SUPERFAMILY SSF82693 137 308 2.41E-11 T 12-10-2018 VAPA_1c06800 8ea756e5a90d05c1163258f951d57dbc 1014 Pfam PF00873 AcrB/AcrD/AcrF family 5 1001 7.8E-226 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 VAPA_2c10690 2c54f7cdfe65171ce6033218767de2bb 502 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 12 34 7.8E-38 T 12-10-2018 VAPA_2c10690 2c54f7cdfe65171ce6033218767de2bb 502 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 302 318 7.8E-38 T 12-10-2018 VAPA_2c10690 2c54f7cdfe65171ce6033218767de2bb 502 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 287 302 7.8E-38 T 12-10-2018 VAPA_2c10690 2c54f7cdfe65171ce6033218767de2bb 502 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 320 338 7.8E-38 T 12-10-2018 VAPA_2c10690 2c54f7cdfe65171ce6033218767de2bb 502 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 165 180 7.8E-38 T 12-10-2018 VAPA_2c10690 2c54f7cdfe65171ce6033218767de2bb 502 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 338 354 7.8E-38 T 12-10-2018 VAPA_2c10690 2c54f7cdfe65171ce6033218767de2bb 502 SUPERFAMILY SSF51905 12 376 1.2E-60 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_2c10690 2c54f7cdfe65171ce6033218767de2bb 502 Pfam PF01494 FAD binding domain 12 351 1.0E-66 T 12-10-2018 IPR002938 FAD-binding domain GO:0071949 VAPA_2c10690 2c54f7cdfe65171ce6033218767de2bb 502 Gene3D G3DSA:3.30.70.2450 194 276 6.4E-85 T 12-10-2018 VAPA_2c10690 2c54f7cdfe65171ce6033218767de2bb 502 Gene3D G3DSA:3.50.50.60 12 350 6.4E-85 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c14060 9c2202853b3db924ea6ba15ea7247a0b 385 Pfam PF01070 FMN-dependent dehydrogenase 17 379 1.2E-131 T 12-10-2018 IPR000262 FMN-dependent dehydrogenase GO:0016491 Reactome: R-HSA-9033241 VAPA_1c14060 9c2202853b3db924ea6ba15ea7247a0b 385 ProSitePatterns PS00557 FMN-dependent alpha-hydroxy acid dehydrogenases active site. 278 284 - T 12-10-2018 IPR008259 FMN-dependent alpha-hydroxy acid dehydrogenase, active site GO:0016491|GO:0055114 Reactome: R-HSA-9033241 VAPA_1c14060 9c2202853b3db924ea6ba15ea7247a0b 385 SUPERFAMILY SSF51395 6 378 5.07E-105 T 12-10-2018 VAPA_1c14060 9c2202853b3db924ea6ba15ea7247a0b 385 Gene3D G3DSA:3.20.20.70 6 382 2.6E-132 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 VAPA_1c14060 9c2202853b3db924ea6ba15ea7247a0b 385 PIRSF PIRSF000138 2 384 1.8E-125 T 12-10-2018 IPR012133 Alpha-hydroxy acid dehydrogenase, FMN-dependent GO:0010181|GO:0016491|GO:0055114 Reactome: R-HSA-9033241 VAPA_1c03800 3586b68b71439310a895269fd641ce02 252 Pfam PF01925 Sulfite exporter TauE/SafE 8 244 9.9E-42 T 12-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 VAPA_1c28800 7d8ee19ae3bd94605175782a7fddb47b 182 SUPERFAMILY SSF88946 8 110 2.62E-18 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 VAPA_1c28800 7d8ee19ae3bd94605175782a7fddb47b 182 Pfam PF04542 Sigma-70 region 2 24 93 7.0E-11 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 VAPA_1c28800 7d8ee19ae3bd94605175782a7fddb47b 182 Gene3D G3DSA:1.10.1740.10 3 93 2.7E-14 T 12-10-2018 VAPA_1c28800 7d8ee19ae3bd94605175782a7fddb47b 182 SUPERFAMILY SSF88659 116 177 1.08E-12 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like VAPA_1c28800 7d8ee19ae3bd94605175782a7fddb47b 182 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 22 176 4.6E-20 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 VAPA_1c28800 7d8ee19ae3bd94605175782a7fddb47b 182 Pfam PF08281 Sigma-70, region 4 122 173 6.5E-14 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 VAPA_1c28800 7d8ee19ae3bd94605175782a7fddb47b 182 Gene3D G3DSA:1.10.10.10 107 180 1.3E-15 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c42490 52e5094d65dd66f17d7948a221618a3a 279 SUPERFAMILY SSF52374 1 274 7.5E-97 T 12-10-2018 VAPA_1c42490 52e5094d65dd66f17d7948a221618a3a 279 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 22 58 2.9E-7 T 12-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 VAPA_1c42490 52e5094d65dd66f17d7948a221618a3a 279 Gene3D G3DSA:3.30.1300.10 175 272 3.6E-31 T 12-10-2018 VAPA_1c42490 52e5094d65dd66f17d7948a221618a3a 279 Pfam PF02569 Pantoate-beta-alanine ligase 3 272 7.4E-93 T 12-10-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 VAPA_1c42490 52e5094d65dd66f17d7948a221618a3a 279 Hamap MF_00158 Pantothenate synthetase [panC]. 2 274 36.345 T 12-10-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 VAPA_1c42490 52e5094d65dd66f17d7948a221618a3a 279 Gene3D G3DSA:3.40.50.620 2 174 2.2E-67 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold VAPA_1c42490 52e5094d65dd66f17d7948a221618a3a 279 TIGRFAM TIGR00018 panC: pantoate--beta-alanine ligase 2 274 2.4E-85 T 12-10-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 VAPA_1c31870 f1745cede35e58da48eccaf7ee2f0f10 273 SMART SM00450 125 230 4.4E-9 T 12-10-2018 IPR001763 Rhodanese-like domain VAPA_1c31870 f1745cede35e58da48eccaf7ee2f0f10 273 Gene3D G3DSA:3.30.70.100 4 106 4.1E-32 T 12-10-2018 VAPA_1c31870 f1745cede35e58da48eccaf7ee2f0f10 273 Pfam PF00581 Rhodanese-like domain 131 224 5.3E-6 T 12-10-2018 IPR001763 Rhodanese-like domain VAPA_1c31870 f1745cede35e58da48eccaf7ee2f0f10 273 SUPERFAMILY SSF52821 110 244 2.74E-23 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily VAPA_1c31870 f1745cede35e58da48eccaf7ee2f0f10 273 Gene3D G3DSA:3.40.250.10 109 264 3.3E-33 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily VAPA_1c31870 f1745cede35e58da48eccaf7ee2f0f10 273 Hamap MF_00469 UPF0176 protein YceA [yceA]. 12 270 33.174 T 12-10-2018 IPR020936 Uncharacterised protein family UPF0176 VAPA_1c22970 9cb69dc73a0e4cb933f719c970746288 350 TIGRFAM TIGR00750 lao: LAO/AO transport system ATPase 21 341 3.3E-100 T 12-10-2018 IPR005129 SIMIBI class G3E GTPase, ArgK/MeaB GO:0003924|GO:0005525 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 VAPA_1c22970 9cb69dc73a0e4cb933f719c970746288 350 Pfam PF03308 ArgK protein 25 310 2.2E-102 T 12-10-2018 VAPA_1c22970 9cb69dc73a0e4cb933f719c970746288 350 SUPERFAMILY SSF52540 20 341 9.33E-85 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c22970 9cb69dc73a0e4cb933f719c970746288 350 Gene3D G3DSA:3.40.50.300 55 279 6.6E-77 T 12-10-2018 VAPA_1c22970 9cb69dc73a0e4cb933f719c970746288 350 Gene3D G3DSA:1.20.5.170 7 54 1.6E-12 T 12-10-2018 VAPA_1c22970 9cb69dc73a0e4cb933f719c970746288 350 Gene3D G3DSA:1.10.287.130 282 346 4.2E-18 T 12-10-2018 VAPA_1c20710 6e84b4cc759bd6042df1da9da5800048 752 TIGRFAM TIGR01007 eps_fam: capsular exopolysaccharide family 536 738 4.7E-47 T 12-10-2018 IPR005702 Exopolysaccharide synthesis protein GO:0045226 VAPA_1c20710 6e84b4cc759bd6042df1da9da5800048 752 Pfam PF13614 AAA domain 565 682 1.4E-11 T 12-10-2018 IPR025669 AAA domain VAPA_1c20710 6e84b4cc759bd6042df1da9da5800048 752 TIGRFAM TIGR01005 eps_transp_fam: exopolysaccharide transport protein family 25 751 1.4E-146 T 12-10-2018 IPR005700 Exopolysaccharide biosynthesis protein ExoP-like GO:0045226 VAPA_1c20710 6e84b4cc759bd6042df1da9da5800048 752 Pfam PF02706 Chain length determinant protein 27 117 1.2E-14 T 12-10-2018 IPR003856 Polysaccharide chain length determinant N-terminal domain GO:0009103|GO:0016020 VAPA_1c20710 6e84b4cc759bd6042df1da9da5800048 752 SUPERFAMILY SSF52540 555 734 7.98E-39 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c20710 6e84b4cc759bd6042df1da9da5800048 752 Gene3D G3DSA:3.40.50.300 474 750 7.8E-71 T 12-10-2018 VAPA_1c20710 6e84b4cc759bd6042df1da9da5800048 752 Pfam PF13807 G-rich domain on putative tyrosine kinase 399 478 2.5E-28 T 12-10-2018 IPR032807 Tyrosine kinase, G-rich domain VAPA_2c04200 544466d6d9dee22309a64475379cae3e 363 SUPERFAMILY SSF53098 139 307 2.02E-38 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily VAPA_2c04200 544466d6d9dee22309a64475379cae3e 363 Gene3D G3DSA:3.30.420.10 136 305 1.5E-9 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 VAPA_2c04200 544466d6d9dee22309a64475379cae3e 363 Pfam PF00665 Integrase core domain 139 256 1.8E-20 T 12-10-2018 IPR001584 Integrase, catalytic core GO:0015074 VAPA_2c13090 544466d6d9dee22309a64475379cae3e 363 SUPERFAMILY SSF53098 139 307 2.02E-38 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily VAPA_2c13090 544466d6d9dee22309a64475379cae3e 363 Gene3D G3DSA:3.30.420.10 136 305 1.5E-9 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 VAPA_2c13090 544466d6d9dee22309a64475379cae3e 363 Pfam PF00665 Integrase core domain 139 256 1.8E-20 T 12-10-2018 IPR001584 Integrase, catalytic core GO:0015074 VAPA_1c31510 544466d6d9dee22309a64475379cae3e 363 SUPERFAMILY SSF53098 139 307 2.02E-38 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily VAPA_1c31510 544466d6d9dee22309a64475379cae3e 363 Gene3D G3DSA:3.30.420.10 136 305 1.5E-9 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 VAPA_1c31510 544466d6d9dee22309a64475379cae3e 363 Pfam PF00665 Integrase core domain 139 256 1.8E-20 T 12-10-2018 IPR001584 Integrase, catalytic core GO:0015074 VAPA_2c07460 544466d6d9dee22309a64475379cae3e 363 SUPERFAMILY SSF53098 139 307 2.02E-38 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily VAPA_2c07460 544466d6d9dee22309a64475379cae3e 363 Gene3D G3DSA:3.30.420.10 136 305 1.5E-9 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 VAPA_2c07460 544466d6d9dee22309a64475379cae3e 363 Pfam PF00665 Integrase core domain 139 256 1.8E-20 T 12-10-2018 IPR001584 Integrase, catalytic core GO:0015074 VAPA_2c05580 544466d6d9dee22309a64475379cae3e 363 SUPERFAMILY SSF53098 139 307 2.02E-38 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily VAPA_2c05580 544466d6d9dee22309a64475379cae3e 363 Gene3D G3DSA:3.30.420.10 136 305 1.5E-9 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 VAPA_2c05580 544466d6d9dee22309a64475379cae3e 363 Pfam PF00665 Integrase core domain 139 256 1.8E-20 T 12-10-2018 IPR001584 Integrase, catalytic core GO:0015074 VAPA_2c11480 46df22c765a49f42f4901ffab26467b3 755 Pfam PF08448 PAS fold 206 301 1.9E-12 T 12-10-2018 IPR013656 PAS fold-4 VAPA_2c11480 46df22c765a49f42f4901ffab26467b3 755 SUPERFAMILY SSF141868 488 737 6.41E-72 T 12-10-2018 IPR035919 EAL domain superfamily VAPA_2c11480 46df22c765a49f42f4901ffab26467b3 755 Gene3D G3DSA:3.30.70.270 304 478 4.6E-56 T 12-10-2018 VAPA_2c11480 46df22c765a49f42f4901ffab26467b3 755 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 228 307 8.6E-10 T 12-10-2018 IPR000014 PAS domain VAPA_2c11480 46df22c765a49f42f4901ffab26467b3 755 SUPERFAMILY SSF55073 316 474 7.77E-49 T 12-10-2018 IPR029787 Nucleotide cyclase VAPA_2c11480 46df22c765a49f42f4901ffab26467b3 755 Pfam PF00563 EAL domain 489 724 8.6E-62 T 12-10-2018 IPR001633 EAL domain VAPA_2c11480 46df22c765a49f42f4901ffab26467b3 755 SUPERFAMILY SSF55785 187 303 4.67E-16 T 12-10-2018 IPR035965 PAS domain superfamily VAPA_2c11480 46df22c765a49f42f4901ffab26467b3 755 SMART SM00086 258 300 5.7E-8 T 12-10-2018 IPR001610 PAC motif VAPA_2c11480 46df22c765a49f42f4901ffab26467b3 755 SMART SM00267 300 472 5.2E-61 T 12-10-2018 IPR000160 GGDEF domain VAPA_2c11480 46df22c765a49f42f4901ffab26467b3 755 Gene3D G3DSA:3.30.450.20 184 298 1.4E-18 T 12-10-2018 VAPA_2c11480 46df22c765a49f42f4901ffab26467b3 755 Pfam PF00072 Response regulator receiver domain 50 148 1.0E-8 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_2c11480 46df22c765a49f42f4901ffab26467b3 755 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 307 470 1.7E-40 T 12-10-2018 IPR000160 GGDEF domain VAPA_2c11480 46df22c765a49f42f4901ffab26467b3 755 SMART SM00052 482 730 1.9E-86 T 12-10-2018 IPR001633 EAL domain VAPA_2c11480 46df22c765a49f42f4901ffab26467b3 755 Gene3D G3DSA:3.20.20.450 483 738 8.9E-84 T 12-10-2018 IPR035919 EAL domain superfamily VAPA_2c11480 46df22c765a49f42f4901ffab26467b3 755 Gene3D G3DSA:3.40.50.2300 1 154 9.8E-24 T 12-10-2018 VAPA_2c11480 46df22c765a49f42f4901ffab26467b3 755 Pfam PF00990 Diguanylate cyclase, GGDEF domain 311 468 6.3E-44 T 12-10-2018 IPR000160 GGDEF domain VAPA_2c11480 46df22c765a49f42f4901ffab26467b3 755 SUPERFAMILY SSF52172 5 190 4.04E-15 T 12-10-2018 IPR011006 CheY-like superfamily VAPA_1c35240 77ffb0f28b51d4e031c43bbc2e4f464e 265 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 41 258 2.6E-55 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF VAPA_1c35240 77ffb0f28b51d4e031c43bbc2e4f464e 265 Gene3D G3DSA:3.40.190.10 127 218 3.1E-58 T 12-10-2018 VAPA_1c35240 77ffb0f28b51d4e031c43bbc2e4f464e 265 Gene3D G3DSA:3.40.190.10 35 253 3.1E-58 T 12-10-2018 VAPA_1c35240 77ffb0f28b51d4e031c43bbc2e4f464e 265 SMART SM00079 42 259 0.0091 T 12-10-2018 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 VAPA_1c35240 77ffb0f28b51d4e031c43bbc2e4f464e 265 SMART SM00062 40 260 2.9E-47 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF VAPA_1c35240 77ffb0f28b51d4e031c43bbc2e4f464e 265 SUPERFAMILY SSF53850 13 260 1.77E-59 T 12-10-2018 VAPA_1c35330 2abdda69acd2b65631d1c1a9d33a948d 373 SMART SM00612 302 347 0.0061 T 12-10-2018 IPR006652 Kelch repeat type 1 GO:0005515 VAPA_1c35330 2abdda69acd2b65631d1c1a9d33a948d 373 SMART SM00612 143 191 7.1E-4 T 12-10-2018 IPR006652 Kelch repeat type 1 GO:0005515 VAPA_1c35330 2abdda69acd2b65631d1c1a9d33a948d 373 SMART SM00612 192 242 0.33 T 12-10-2018 IPR006652 Kelch repeat type 1 GO:0005515 VAPA_1c35330 2abdda69acd2b65631d1c1a9d33a948d 373 SMART SM00612 95 142 2.4 T 12-10-2018 IPR006652 Kelch repeat type 1 GO:0005515 VAPA_1c35330 2abdda69acd2b65631d1c1a9d33a948d 373 SMART SM00612 243 291 0.015 T 12-10-2018 IPR006652 Kelch repeat type 1 GO:0005515 VAPA_1c35330 2abdda69acd2b65631d1c1a9d33a948d 373 Gene3D G3DSA:2.120.10.80 67 207 1.3E-30 T 12-10-2018 IPR015915 Kelch-type beta propeller GO:0005515 VAPA_1c35330 2abdda69acd2b65631d1c1a9d33a948d 373 Gene3D G3DSA:2.120.10.80 208 367 4.3E-40 T 12-10-2018 IPR015915 Kelch-type beta propeller GO:0005515 VAPA_1c35330 2abdda69acd2b65631d1c1a9d33a948d 373 Pfam PF01344 Kelch motif 280 333 2.9E-5 T 12-10-2018 IPR006652 Kelch repeat type 1 GO:0005515 VAPA_1c35330 2abdda69acd2b65631d1c1a9d33a948d 373 Pfam PF01344 Kelch motif 133 178 4.3E-5 T 12-10-2018 IPR006652 Kelch repeat type 1 GO:0005515 VAPA_1c35330 2abdda69acd2b65631d1c1a9d33a948d 373 SUPERFAMILY SSF117281 71 300 3.14E-48 T 12-10-2018 IPR015915 Kelch-type beta propeller GO:0005515 VAPA_1c21920 462e764333eb0fd93ebfebd5ce256dfc 318 Gene3D G3DSA:3.20.20.70 3 307 5.1E-78 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 VAPA_1c21920 462e764333eb0fd93ebfebd5ce256dfc 318 SMART SM01130 5 305 9.1E-66 T 12-10-2018 IPR002220 DapA-like GO:0016829 VAPA_1c21920 462e764333eb0fd93ebfebd5ce256dfc 318 PIRSF PIRSF001365 3 313 1.2E-64 T 12-10-2018 IPR002220 DapA-like GO:0016829 VAPA_1c21920 462e764333eb0fd93ebfebd5ce256dfc 318 Pfam PF00701 Dihydrodipicolinate synthetase family 7 301 2.3E-37 T 12-10-2018 IPR002220 DapA-like GO:0016829 VAPA_1c21920 462e764333eb0fd93ebfebd5ce256dfc 318 SUPERFAMILY SSF51569 6 306 4.29E-64 T 12-10-2018 VAPA_1c21920 462e764333eb0fd93ebfebd5ce256dfc 318 PRINTS PR00146 Dihydrodipicolinate synthase signature 40 61 1.1E-7 T 12-10-2018 IPR002220 DapA-like GO:0016829 VAPA_1c21920 462e764333eb0fd93ebfebd5ce256dfc 318 PRINTS PR00146 Dihydrodipicolinate synthase signature 136 153 1.1E-7 T 12-10-2018 IPR002220 DapA-like GO:0016829 VAPA_1c21920 462e764333eb0fd93ebfebd5ce256dfc 318 PRINTS PR00146 Dihydrodipicolinate synthase signature 75 93 1.1E-7 T 12-10-2018 IPR002220 DapA-like GO:0016829 VAPA_2c06940 a022fa1a9d3671e293f9ea5b16351e84 528 SMART SM00382 48 244 4.8E-10 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_2c06940 a022fa1a9d3671e293f9ea5b16351e84 528 ProSitePatterns PS00211 ABC transporters family signature. 423 437 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_2c06940 a022fa1a9d3671e293f9ea5b16351e84 528 Gene3D G3DSA:3.40.50.300 15 277 5.7E-54 T 12-10-2018 VAPA_2c06940 a022fa1a9d3671e293f9ea5b16351e84 528 Gene3D G3DSA:3.40.50.300 284 522 2.5E-42 T 12-10-2018 VAPA_2c06940 a022fa1a9d3671e293f9ea5b16351e84 528 Pfam PF00005 ABC transporter 39 195 1.0E-27 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_2c06940 a022fa1a9d3671e293f9ea5b16351e84 528 SUPERFAMILY SSF52540 292 512 1.22E-42 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_2c06940 a022fa1a9d3671e293f9ea5b16351e84 528 Pfam PF00005 ABC transporter 296 450 1.8E-13 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_2c06940 a022fa1a9d3671e293f9ea5b16351e84 528 SUPERFAMILY SSF52540 23 256 1.05E-52 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c36520 78d5247df0b32f8a61800869a98467c7 149 Gene3D G3DSA:1.10.1510.10 1 90 6.7E-32 T 12-10-2018 VAPA_1c36520 78d5247df0b32f8a61800869a98467c7 149 Pfam PF09424 Yqey-like protein 4 146 1.5E-55 T 12-10-2018 IPR019004 Uncharacterised protein YqeY/AIM41 VAPA_1c36520 78d5247df0b32f8a61800869a98467c7 149 Gene3D G3DSA:1.10.10.410 91 147 1.3E-18 T 12-10-2018 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal VAPA_1c36520 78d5247df0b32f8a61800869a98467c7 149 SUPERFAMILY SSF89095 1 146 1.15E-44 T 12-10-2018 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-like GO:0016884 VAPA_1c28520 2ec7e473ff62c2c6810025a51027027f 249 SUPERFAMILY SSF48452 134 243 1.88E-14 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 VAPA_1c28520 2ec7e473ff62c2c6810025a51027027f 249 Pfam PF13525 Outer membrane lipoprotein 128 249 2.7E-10 T 12-10-2018 IPR039565 Outer membrane lipoprotein BamD-like VAPA_1c28520 2ec7e473ff62c2c6810025a51027027f 249 TIGRFAM TIGR02795 tol_pal_ybgF: tol-pal system protein YbgF 128 245 4.7E-34 T 12-10-2018 IPR014162 Cell division coordinator CpoB, C-terminal VAPA_1c28520 2ec7e473ff62c2c6810025a51027027f 249 Gene3D G3DSA:1.25.40.10 128 249 3.1E-28 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 VAPA_1c28520 2ec7e473ff62c2c6810025a51027027f 249 Hamap MF_02066 Cell division coordinator CpoB [cpoB]. 7 248 18.864 T 12-10-2018 IPR034706 Cell division coordinator CpoB GO:0051301 VAPA_1c39220 1dbf792e1e8dfa3e30d7f246411aab8b 330 SUPERFAMILY SSF55447 225 324 1.44E-27 T 12-10-2018 IPR036683 CO dehydrogenase flavoprotein, C-terminal domain superfamily VAPA_1c39220 1dbf792e1e8dfa3e30d7f246411aab8b 330 SUPERFAMILY SSF56176 1 218 5.29E-48 T 12-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 VAPA_1c39220 1dbf792e1e8dfa3e30d7f246411aab8b 330 SMART SM01092 227 325 2.0E-31 T 12-10-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal VAPA_1c39220 1dbf792e1e8dfa3e30d7f246411aab8b 330 Gene3D G3DSA:3.30.465.10 1 219 8.1E-67 T 12-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 VAPA_1c39220 1dbf792e1e8dfa3e30d7f246411aab8b 330 Gene3D G3DSA:3.30.390.50 224 327 6.5E-29 T 12-10-2018 VAPA_1c39220 1dbf792e1e8dfa3e30d7f246411aab8b 330 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 3 218 1.2E-42 T 12-10-2018 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 VAPA_1c39220 1dbf792e1e8dfa3e30d7f246411aab8b 330 Pfam PF03450 CO dehydrogenase flavoprotein C-terminal domain 228 323 2.3E-17 T 12-10-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal VAPA_1c49090 8b1acb3b7f7344afe8aa8a6f38c5b889 332 Gene3D G3DSA:3.40.710.10 6 313 6.0E-61 T 12-10-2018 VAPA_1c49090 8b1acb3b7f7344afe8aa8a6f38c5b889 332 Pfam PF00144 Beta-lactamase 52 299 9.1E-24 T 12-10-2018 IPR001466 Beta-lactamase-related VAPA_1c49090 8b1acb3b7f7344afe8aa8a6f38c5b889 332 SUPERFAMILY SSF56601 11 309 1.58E-62 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like VAPA_1c26200 eac604bd1ba6bf9dd19de9beb9ad7b5b 544 Gene3D G3DSA:3.40.50.1820 1 539 3.9E-112 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c26200 eac604bd1ba6bf9dd19de9beb9ad7b5b 544 Pfam PF00135 Carboxylesterase family 4 520 1.7E-82 T 12-10-2018 IPR002018 Carboxylesterase, type B VAPA_1c26200 eac604bd1ba6bf9dd19de9beb9ad7b5b 544 ProSitePatterns PS00122 Carboxylesterases type-B serine active site. 192 207 - T 12-10-2018 IPR019826 Carboxylesterase type B, active site VAPA_1c26200 eac604bd1ba6bf9dd19de9beb9ad7b5b 544 ProSitePatterns PS00941 Carboxylesterases type-B signature 2. 91 101 - T 12-10-2018 IPR019819 Carboxylesterase type B, conserved site VAPA_1c26200 eac604bd1ba6bf9dd19de9beb9ad7b5b 544 SUPERFAMILY SSF53474 2 525 1.02E-92 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c10780 15d1e0c65fbe3fc225bebed6afe3bd01 410 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 179 408 1.0E-75 T 12-10-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0016746 Reactome: R-HSA-389661 VAPA_1c10780 15d1e0c65fbe3fc225bebed6afe3bd01 410 Gene3D G3DSA:4.10.320.10 111 164 1.9E-12 T 12-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 VAPA_1c10780 15d1e0c65fbe3fc225bebed6afe3bd01 410 Gene3D G3DSA:3.30.559.10 165 406 3.3E-79 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 VAPA_1c10780 15d1e0c65fbe3fc225bebed6afe3bd01 410 Gene3D G3DSA:2.40.50.100 2 104 2.8E-20 T 12-10-2018 VAPA_1c10780 15d1e0c65fbe3fc225bebed6afe3bd01 410 SUPERFAMILY SSF51230 3 96 4.45E-24 T 12-10-2018 IPR011053 Single hybrid motif VAPA_1c10780 15d1e0c65fbe3fc225bebed6afe3bd01 410 SUPERFAMILY SSF47005 118 160 2.09E-8 T 12-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 VAPA_1c10780 15d1e0c65fbe3fc225bebed6afe3bd01 410 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 28 57 - T 12-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 VAPA_1c10780 15d1e0c65fbe3fc225bebed6afe3bd01 410 Pfam PF00364 Biotin-requiring enzyme 4 77 2.8E-18 T 12-10-2018 IPR000089 Biotin/lipoyl attachment VAPA_1c10780 15d1e0c65fbe3fc225bebed6afe3bd01 410 SUPERFAMILY SSF52777 170 408 6.23E-75 T 12-10-2018 VAPA_1c10780 15d1e0c65fbe3fc225bebed6afe3bd01 410 Pfam PF02817 e3 binding domain 123 157 7.3E-10 T 12-10-2018 IPR004167 Peripheral subunit-binding domain GO:0016746 Reactome: R-HSA-389661 VAPA_1c17400 59037097acb8dde4ede55e84f2dcac57 359 Gene3D G3DSA:1.10.287.130 138 196 1.9E-13 T 12-10-2018 VAPA_1c17400 59037097acb8dde4ede55e84f2dcac57 359 Gene3D G3DSA:3.30.565.10 199 358 3.5E-32 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_1c17400 59037097acb8dde4ede55e84f2dcac57 359 SMART SM00387 240 359 1.2E-21 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase VAPA_1c17400 59037097acb8dde4ede55e84f2dcac57 359 Pfam PF00512 His Kinase A (phospho-acceptor) domain 137 196 2.3E-13 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 VAPA_1c17400 59037097acb8dde4ede55e84f2dcac57 359 Gene3D G3DSA:3.30.450.20 15 118 3.7E-6 T 12-10-2018 VAPA_1c17400 59037097acb8dde4ede55e84f2dcac57 359 SUPERFAMILY SSF55874 204 357 3.41E-30 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_1c17400 59037097acb8dde4ede55e84f2dcac57 359 SMART SM00388 135 200 8.2E-13 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 VAPA_1c17400 59037097acb8dde4ede55e84f2dcac57 359 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 240 358 1.8E-13 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase VAPA_1c17400 59037097acb8dde4ede55e84f2dcac57 359 PRINTS PR00344 Bacterial sensor protein C-terminal signature 292 306 1.4E-10 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c17400 59037097acb8dde4ede55e84f2dcac57 359 PRINTS PR00344 Bacterial sensor protein C-terminal signature 310 320 1.4E-10 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c17400 59037097acb8dde4ede55e84f2dcac57 359 PRINTS PR00344 Bacterial sensor protein C-terminal signature 321 339 1.4E-10 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c17400 59037097acb8dde4ede55e84f2dcac57 359 PRINTS PR00344 Bacterial sensor protein C-terminal signature 344 357 1.4E-10 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c17400 59037097acb8dde4ede55e84f2dcac57 359 SUPERFAMILY SSF55785 17 101 3.32E-7 T 12-10-2018 IPR035965 PAS domain superfamily VAPA_1c17400 59037097acb8dde4ede55e84f2dcac57 359 SUPERFAMILY SSF47384 124 196 1.96E-14 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 VAPA_1c42350 982cede76d276c612950708c6c0effa8 698 Pfam PF01588 Putative tRNA binding domain 598 687 2.5E-21 T 12-10-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 VAPA_1c42350 982cede76d276c612950708c6c0effa8 698 Hamap MF_00098 Methionine--tRNA ligase [metG]. 5 562 37.874 T 12-10-2018 IPR023458 Methionine-tRNA ligase, type 1 GO:0004825 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 VAPA_1c42350 982cede76d276c612950708c6c0effa8 698 SUPERFAMILY SSF47323 403 561 7.66E-37 T 12-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 VAPA_1c42350 982cede76d276c612950708c6c0effa8 698 Pfam PF09334 tRNA synthetases class I (M) 8 410 7.5E-140 T 12-10-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 VAPA_1c42350 982cede76d276c612950708c6c0effa8 698 Gene3D G3DSA:2.40.50.140 582 698 4.9E-32 T 12-10-2018 VAPA_1c42350 982cede76d276c612950708c6c0effa8 698 TIGRFAM TIGR00398 metG: methionine--tRNA ligase 8 548 2.4E-158 T 12-10-2018 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 VAPA_1c42350 982cede76d276c612950708c6c0effa8 698 TIGRFAM TIGR00399 metG_C_term: methionine--tRNA ligase, beta subunit 572 698 1.3E-38 T 12-10-2018 IPR004495 Methionyl-tRNA synthetase, beta subunit, C-terminal GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 VAPA_1c42350 982cede76d276c612950708c6c0effa8 698 PRINTS PR01041 Methionyl-tRNA synthetase signature 41 55 2.8E-23 T 12-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 VAPA_1c42350 982cede76d276c612950708c6c0effa8 698 PRINTS PR01041 Methionyl-tRNA synthetase signature 398 409 2.8E-23 T 12-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 VAPA_1c42350 982cede76d276c612950708c6c0effa8 698 PRINTS PR01041 Methionyl-tRNA synthetase signature 259 270 2.8E-23 T 12-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 VAPA_1c42350 982cede76d276c612950708c6c0effa8 698 PRINTS PR01041 Methionyl-tRNA synthetase signature 304 319 2.8E-23 T 12-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 VAPA_1c42350 982cede76d276c612950708c6c0effa8 698 PRINTS PR01041 Methionyl-tRNA synthetase signature 9 22 2.8E-23 T 12-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 VAPA_1c42350 982cede76d276c612950708c6c0effa8 698 PRINTS PR01041 Methionyl-tRNA synthetase signature 89 100 2.8E-23 T 12-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 VAPA_1c42350 982cede76d276c612950708c6c0effa8 698 Gene3D G3DSA:2.20.28.20 141 175 1.8E-137 T 12-10-2018 IPR029038 Methionyl-tRNA synthetase, Zn-domain KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 VAPA_1c42350 982cede76d276c612950708c6c0effa8 698 SUPERFAMILY SSF57770 141 175 2.22E-12 T 12-10-2018 IPR029038 Methionyl-tRNA synthetase, Zn-domain KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 VAPA_1c42350 982cede76d276c612950708c6c0effa8 698 Gene3D G3DSA:3.40.50.620 8 398 1.8E-137 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold VAPA_1c42350 982cede76d276c612950708c6c0effa8 698 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 14 25 - T 12-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 VAPA_1c42350 982cede76d276c612950708c6c0effa8 698 SUPERFAMILY SSF50249 591 697 9.06E-29 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold VAPA_1c42350 982cede76d276c612950708c6c0effa8 698 Gene3D G3DSA:1.10.730.10 403 542 3.1E-31 T 12-10-2018 VAPA_1c42350 982cede76d276c612950708c6c0effa8 698 SUPERFAMILY SSF52374 5 398 2.09E-89 T 12-10-2018 VAPA_1c40320 4dad389d049f7a60d112fbeda0ea726a 302 Gene3D G3DSA:1.10.10.10 1 88 1.2E-29 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c40320 4dad389d049f7a60d112fbeda0ea726a 302 Gene3D G3DSA:3.40.190.10 170 268 3.0E-56 T 12-10-2018 VAPA_1c40320 4dad389d049f7a60d112fbeda0ea726a 302 SUPERFAMILY SSF46785 2 86 1.39E-20 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c40320 4dad389d049f7a60d112fbeda0ea726a 302 Gene3D G3DSA:3.40.190.10 92 292 3.0E-56 T 12-10-2018 VAPA_1c40320 4dad389d049f7a60d112fbeda0ea726a 302 SUPERFAMILY SSF53850 90 295 6.39E-36 T 12-10-2018 VAPA_1c40320 4dad389d049f7a60d112fbeda0ea726a 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 23 34 4.6E-5 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c40320 4dad389d049f7a60d112fbeda0ea726a 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 44 4.6E-5 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c40320 4dad389d049f7a60d112fbeda0ea726a 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 44 55 4.6E-5 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c40320 4dad389d049f7a60d112fbeda0ea726a 302 Pfam PF03466 LysR substrate binding domain 93 295 2.3E-23 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_1c40320 4dad389d049f7a60d112fbeda0ea726a 302 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 67 7.9E-19 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c14950 befa15cf7eddf4c7bd01be4490014fa4 228 Pfam PF14622 Ribonuclease-III-like 19 137 6.2E-36 T 12-10-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 Reactome: R-HSA-203927 VAPA_1c14950 befa15cf7eddf4c7bd01be4490014fa4 228 Gene3D G3DSA:1.10.1520.10 5 144 1.6E-44 T 12-10-2018 IPR036389 Ribonuclease III, endonuclease domain superfamily GO:0004525|GO:0006396 VAPA_1c14950 befa15cf7eddf4c7bd01be4490014fa4 228 TIGRFAM TIGR02191 RNaseIII: ribonuclease III 8 221 2.0E-65 T 12-10-2018 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 VAPA_1c14950 befa15cf7eddf4c7bd01be4490014fa4 228 SMART SM00535 20 147 1.4E-44 T 12-10-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 Reactome: R-HSA-203927 VAPA_1c14950 befa15cf7eddf4c7bd01be4490014fa4 228 Hamap MF_00104 Ribonuclease 3 [rnc]. 8 219 28.216 T 12-10-2018 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 VAPA_1c14950 befa15cf7eddf4c7bd01be4490014fa4 228 Pfam PF00035 Double-stranded RNA binding motif 155 219 3.1E-7 T 12-10-2018 IPR014720 Double-stranded RNA-binding domain VAPA_1c14950 befa15cf7eddf4c7bd01be4490014fa4 228 Gene3D G3DSA:3.30.160.20 153 224 7.7E-15 T 12-10-2018 VAPA_1c14950 befa15cf7eddf4c7bd01be4490014fa4 228 SMART SM00358 155 223 6.8E-13 T 12-10-2018 IPR014720 Double-stranded RNA-binding domain VAPA_1c14950 befa15cf7eddf4c7bd01be4490014fa4 228 ProSitePatterns PS00517 Ribonuclease III family signature. 37 45 - T 12-10-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 Reactome: R-HSA-203927 VAPA_1c14950 befa15cf7eddf4c7bd01be4490014fa4 228 SUPERFAMILY SSF69065 5 155 1.12E-45 T 12-10-2018 IPR036389 Ribonuclease III, endonuclease domain superfamily GO:0004525|GO:0006396 VAPA_1c14950 befa15cf7eddf4c7bd01be4490014fa4 228 SUPERFAMILY SSF54768 108 222 5.95E-25 T 12-10-2018 VAPA_1c23100 ee7a2c3c4434d2d91bf8eb72c5319127 705 Pfam PF04851 Type III restriction enzyme, res subunit 66 150 1.9E-8 T 12-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 VAPA_1c23100 ee7a2c3c4434d2d91bf8eb72c5319127 705 Pfam PF12344 Ultra-violet resistance protein B 579 621 2.1E-21 T 12-10-2018 IPR024759 UvrB, YAD/RRR-motif-containing domain VAPA_1c23100 ee7a2c3c4434d2d91bf8eb72c5319127 705 SUPERFAMILY SSF52540 32 442 1.44E-132 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c23100 ee7a2c3c4434d2d91bf8eb72c5319127 705 Gene3D G3DSA:3.40.50.300 442 623 6.3E-50 T 12-10-2018 VAPA_1c23100 ee7a2c3c4434d2d91bf8eb72c5319127 705 Pfam PF02151 UvrB/uvrC motif 656 690 5.4E-8 T 12-10-2018 IPR001943 UVR domain GO:0005515 VAPA_1c23100 ee7a2c3c4434d2d91bf8eb72c5319127 705 Gene3D G3DSA:3.40.50.300 296 441 1.4E-48 T 12-10-2018 VAPA_1c23100 ee7a2c3c4434d2d91bf8eb72c5319127 705 SMART SM00487 37 453 2.7E-27 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain VAPA_1c23100 ee7a2c3c4434d2d91bf8eb72c5319127 705 SUPERFAMILY SSF46600 645 691 6.93E-11 T 12-10-2018 IPR036876 UVR domain superfamily VAPA_1c23100 ee7a2c3c4434d2d91bf8eb72c5319127 705 Gene3D G3DSA:3.40.50.300 24 262 1.0E-69 T 12-10-2018 VAPA_1c23100 ee7a2c3c4434d2d91bf8eb72c5319127 705 Gene3D G3DSA:4.10.860.10 637 695 2.6E-20 T 12-10-2018 VAPA_1c23100 ee7a2c3c4434d2d91bf8eb72c5319127 705 SMART SM00490 487 573 2.3E-18 T 12-10-2018 IPR001650 Helicase, C-terminal VAPA_1c23100 ee7a2c3c4434d2d91bf8eb72c5319127 705 Hamap MF_00204 UvrABC system protein B [uvrB]. 31 690 43.27 T 12-10-2018 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006289|GO:0009380|GO:0016887 VAPA_1c23100 ee7a2c3c4434d2d91bf8eb72c5319127 705 SUPERFAMILY SSF52540 65 606 1.74E-36 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c23100 ee7a2c3c4434d2d91bf8eb72c5319127 705 TIGRFAM TIGR00631 uvrb: excinuclease ABC subunit B 33 687 0.0 T 12-10-2018 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006289|GO:0009380|GO:0016887 VAPA_1c23100 ee7a2c3c4434d2d91bf8eb72c5319127 705 Pfam PF00271 Helicase conserved C-terminal domain 468 571 1.6E-17 T 12-10-2018 IPR001650 Helicase, C-terminal VAPA_1c22180 20f17a259ecd66290cae7a20624a9525 487 Pfam PF02321 Outer membrane efflux protein 289 459 2.6E-20 T 12-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 VAPA_1c22180 20f17a259ecd66290cae7a20624a9525 487 Pfam PF02321 Outer membrane efflux protein 64 260 9.0E-22 T 12-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 VAPA_1c22180 20f17a259ecd66290cae7a20624a9525 487 Gene3D G3DSA:1.20.1600.10 55 474 9.1E-111 T 12-10-2018 VAPA_1c22180 20f17a259ecd66290cae7a20624a9525 487 Gene3D G3DSA:2.20.200.10 101 362 9.1E-111 T 12-10-2018 VAPA_1c22180 20f17a259ecd66290cae7a20624a9525 487 SUPERFAMILY SSF56954 3 475 1.01E-93 T 12-10-2018 VAPA_1c22180 20f17a259ecd66290cae7a20624a9525 487 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 13 473 2.8E-85 T 12-10-2018 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0016020|GO:0022857|GO:0055085 VAPA_1c48890 8a8c1dbb55738951a6256eb6be054898 394 PIRSF PIRSF000429 1 394 1.8E-115 T 12-10-2018 IPR002155 Thiolase GO:0016747 VAPA_1c48890 8a8c1dbb55738951a6256eb6be054898 394 ProSitePatterns PS00099 Thiolases active site. 375 388 - T 12-10-2018 IPR020610 Thiolase, active site GO:0016747 VAPA_1c48890 8a8c1dbb55738951a6256eb6be054898 394 Gene3D G3DSA:3.40.47.10 130 390 1.6E-139 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 VAPA_1c48890 8a8c1dbb55738951a6256eb6be054898 394 SUPERFAMILY SSF53901 272 393 2.12E-42 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 VAPA_1c48890 8a8c1dbb55738951a6256eb6be054898 394 Pfam PF02803 Thiolase, C-terminal domain 272 392 8.9E-44 T 12-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 VAPA_1c48890 8a8c1dbb55738951a6256eb6be054898 394 Gene3D G3DSA:3.40.47.10 6 277 1.6E-139 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 VAPA_1c48890 8a8c1dbb55738951a6256eb6be054898 394 SUPERFAMILY SSF53901 5 270 5.26E-77 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 VAPA_1c48890 8a8c1dbb55738951a6256eb6be054898 394 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 7 392 1.5E-127 T 12-10-2018 IPR002155 Thiolase GO:0016747 VAPA_1c48890 8a8c1dbb55738951a6256eb6be054898 394 Pfam PF00108 Thiolase, N-terminal domain 5 264 1.6E-86 T 12-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 VAPA_1c22690 057397cfa74f7dfd2a935b30b3d32b80 323 SUPERFAMILY SSF53850 114 282 1.68E-11 T 12-10-2018 VAPA_1c22690 057397cfa74f7dfd2a935b30b3d32b80 323 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 47 319 1.2E-82 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c22690 057397cfa74f7dfd2a935b30b3d32b80 323 Gene3D G3DSA:3.40.190.10 125 248 6.2E-105 T 12-10-2018 VAPA_1c22690 057397cfa74f7dfd2a935b30b3d32b80 323 Gene3D G3DSA:3.40.190.150 28 313 6.2E-105 T 12-10-2018 VAPA_1c22690 057397cfa74f7dfd2a935b30b3d32b80 323 PIRSF PIRSF017082 1 322 6.6E-77 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c33290 459cbb5a6895e47f674a139a5263d2e8 220 SUPERFAMILY SSF47741 139 208 9.81E-31 T 12-10-2018 IPR036884 [2Fe-2S]-binding domain superfamily VAPA_1c33290 459cbb5a6895e47f674a139a5263d2e8 220 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 59 113 2.8E-7 T 12-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 VAPA_1c33290 459cbb5a6895e47f674a139a5263d2e8 220 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 93 101 - T 12-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 VAPA_1c33290 459cbb5a6895e47f674a139a5263d2e8 220 Gene3D G3DSA:1.10.150.120 129 219 9.4E-32 T 12-10-2018 VAPA_1c33290 459cbb5a6895e47f674a139a5263d2e8 220 Gene3D G3DSA:3.10.20.30 46 128 1.5E-30 T 12-10-2018 IPR012675 Beta-grasp domain superfamily VAPA_1c33290 459cbb5a6895e47f674a139a5263d2e8 220 SUPERFAMILY SSF54292 55 153 1.23E-25 T 12-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 VAPA_1c33290 459cbb5a6895e47f674a139a5263d2e8 220 Pfam PF01799 [2Fe-2S] binding domain 127 200 1.0E-29 T 12-10-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 VAPA_1c21010 96aeabdfe7c9b2cc5a51202cef160a17 1027 Gene3D G3DSA:1.10.8.500 317 360 3.2E-5 T 12-10-2018 VAPA_1c21010 96aeabdfe7c9b2cc5a51202cef160a17 1027 SMART SM00091 614 680 8.9 T 12-10-2018 IPR000014 PAS domain VAPA_1c21010 96aeabdfe7c9b2cc5a51202cef160a17 1027 SMART SM00091 490 554 16.0 T 12-10-2018 IPR000014 PAS domain VAPA_1c21010 96aeabdfe7c9b2cc5a51202cef160a17 1027 SMART SM00091 367 433 0.046 T 12-10-2018 IPR000014 PAS domain VAPA_1c21010 96aeabdfe7c9b2cc5a51202cef160a17 1027 SMART SM00091 739 805 7.0E-7 T 12-10-2018 IPR000014 PAS domain VAPA_1c21010 96aeabdfe7c9b2cc5a51202cef160a17 1027 Gene3D G3DSA:3.30.450.20 44 185 1.4E-18 T 12-10-2018 VAPA_1c21010 96aeabdfe7c9b2cc5a51202cef160a17 1027 Pfam PF02743 Cache domain 44 276 1.5E-19 T 12-10-2018 IPR033479 Double Cache domain 1 VAPA_1c21010 96aeabdfe7c9b2cc5a51202cef160a17 1027 Pfam PF00990 Diguanylate cyclase, GGDEF domain 862 1022 9.4E-46 T 12-10-2018 IPR000160 GGDEF domain VAPA_1c21010 96aeabdfe7c9b2cc5a51202cef160a17 1027 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 860 1023 2.7E-44 T 12-10-2018 IPR000160 GGDEF domain VAPA_1c21010 96aeabdfe7c9b2cc5a51202cef160a17 1027 SUPERFAMILY SSF55785 360 476 6.98E-13 T 12-10-2018 IPR035965 PAS domain superfamily VAPA_1c21010 96aeabdfe7c9b2cc5a51202cef160a17 1027 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 735 858 9.0E-13 T 12-10-2018 IPR000014 PAS domain VAPA_1c21010 96aeabdfe7c9b2cc5a51202cef160a17 1027 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 363 482 2.0E-9 T 12-10-2018 IPR000014 PAS domain VAPA_1c21010 96aeabdfe7c9b2cc5a51202cef160a17 1027 Gene3D G3DSA:3.30.450.20 361 486 2.0E-22 T 12-10-2018 VAPA_1c21010 96aeabdfe7c9b2cc5a51202cef160a17 1027 Gene3D G3DSA:3.30.450.20 610 736 1.1E-12 T 12-10-2018 VAPA_1c21010 96aeabdfe7c9b2cc5a51202cef160a17 1027 Gene3D G3DSA:3.30.450.20 487 609 6.7E-19 T 12-10-2018 VAPA_1c21010 96aeabdfe7c9b2cc5a51202cef160a17 1027 SUPERFAMILY SSF55785 599 725 4.67E-10 T 12-10-2018 IPR035965 PAS domain superfamily VAPA_1c21010 96aeabdfe7c9b2cc5a51202cef160a17 1027 Gene3D G3DSA:3.30.450.20 737 859 1.9E-25 T 12-10-2018 VAPA_1c21010 96aeabdfe7c9b2cc5a51202cef160a17 1027 SMART SM00267 851 1026 4.1E-59 T 12-10-2018 IPR000160 GGDEF domain VAPA_1c21010 96aeabdfe7c9b2cc5a51202cef160a17 1027 SUPERFAMILY SSF55073 867 1025 1.65E-47 T 12-10-2018 IPR029787 Nucleotide cyclase VAPA_1c21010 96aeabdfe7c9b2cc5a51202cef160a17 1027 SUPERFAMILY SSF55785 475 600 9.25E-13 T 12-10-2018 IPR035965 PAS domain superfamily VAPA_1c21010 96aeabdfe7c9b2cc5a51202cef160a17 1027 SUPERFAMILY SSF158472 316 361 7.59E-5 T 12-10-2018 VAPA_1c21010 96aeabdfe7c9b2cc5a51202cef160a17 1027 Gene3D G3DSA:3.30.70.270 860 1026 9.8E-56 T 12-10-2018 VAPA_1c21010 96aeabdfe7c9b2cc5a51202cef160a17 1027 SUPERFAMILY SSF55785 724 849 6.12E-20 T 12-10-2018 IPR035965 PAS domain superfamily VAPA_1c21010 96aeabdfe7c9b2cc5a51202cef160a17 1027 Pfam PF08448 PAS fold 621 729 5.9E-9 T 12-10-2018 IPR013656 PAS fold-4 VAPA_1c21010 96aeabdfe7c9b2cc5a51202cef160a17 1027 Pfam PF08448 PAS fold 374 480 3.7E-14 T 12-10-2018 IPR013656 PAS fold-4 VAPA_1c21010 96aeabdfe7c9b2cc5a51202cef160a17 1027 Pfam PF08448 PAS fold 497 603 1.7E-11 T 12-10-2018 IPR013656 PAS fold-4 VAPA_1c21010 96aeabdfe7c9b2cc5a51202cef160a17 1027 Pfam PF08448 PAS fold 746 852 4.3E-15 T 12-10-2018 IPR013656 PAS fold-4 VAPA_1c17500 7271797756d884e692204fd5c613b9f3 851 Gene3D G3DSA:2.40.50.140 412 530 1.5E-35 T 12-10-2018 VAPA_1c17500 7271797756d884e692204fd5c613b9f3 851 Pfam PF13298 DNA polymerase Ligase (LigD) 38 142 5.7E-37 T 12-10-2018 IPR014144 DNA ligase D, 3'-phosphoesterase domain VAPA_1c17500 7271797756d884e692204fd5c613b9f3 851 TIGRFAM TIGR02779 NHEJ_ligase_lig: DNA ligase D, ligase domain 229 528 1.1E-103 T 12-10-2018 IPR014146 DNA ligase D, ligase domain VAPA_1c17500 7271797756d884e692204fd5c613b9f3 851 TIGRFAM TIGR02776 NHEJ_ligase_prk: DNA ligase D 238 827 5.3E-207 T 12-10-2018 IPR014143 DNA ligase D VAPA_1c17500 7271797756d884e692204fd5c613b9f3 851 Gene3D G3DSA:3.90.920.30 561 840 3.6E-96 T 12-10-2018 VAPA_1c17500 7271797756d884e692204fd5c613b9f3 851 TIGRFAM TIGR02777 LigD_PE_dom: DNA ligase D, 3'-phosphoesterase domain 7 163 2.9E-65 T 12-10-2018 IPR014144 DNA ligase D, 3'-phosphoesterase domain VAPA_1c17500 7271797756d884e692204fd5c613b9f3 851 TIGRFAM TIGR02778 ligD_pol: DNA ligase D, polymerase domain 555 797 1.7E-82 T 12-10-2018 IPR014145 DNA ligase D, polymerase domain VAPA_1c17500 7271797756d884e692204fd5c613b9f3 851 SUPERFAMILY SSF56091 225 410 2.01E-47 T 12-10-2018 VAPA_1c17500 7271797756d884e692204fd5c613b9f3 851 SUPERFAMILY SSF50249 413 532 1.94E-26 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold VAPA_1c17500 7271797756d884e692204fd5c613b9f3 851 Pfam PF04679 ATP dependent DNA ligase C terminal region 431 522 7.2E-23 T 12-10-2018 IPR012309 DNA ligase, ATP-dependent, C-terminal GO:0003910|GO:0006281|GO:0006310 VAPA_1c17500 7271797756d884e692204fd5c613b9f3 851 Gene3D G3DSA:3.30.1490.70 240 408 1.0E-43 T 12-10-2018 VAPA_1c17500 7271797756d884e692204fd5c613b9f3 851 Pfam PF01068 ATP dependent DNA ligase domain 242 410 5.8E-25 T 12-10-2018 IPR012310 DNA ligase, ATP-dependent, central GO:0003910|GO:0005524|GO:0006281|GO:0006310 VAPA_1c17500 7271797756d884e692204fd5c613b9f3 851 Gene3D G3DSA:3.30.470.30 252 367 1.0E-43 T 12-10-2018 VAPA_1c34020 5eea57c37793b69b9f19a6b050bcc186 301 Pfam PF03466 LysR substrate binding domain 90 277 1.2E-33 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_1c34020 5eea57c37793b69b9f19a6b050bcc186 301 SUPERFAMILY SSF46785 1 81 6.42E-19 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c34020 5eea57c37793b69b9f19a6b050bcc186 301 Gene3D G3DSA:1.10.10.10 1 89 5.7E-21 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c34020 5eea57c37793b69b9f19a6b050bcc186 301 SUPERFAMILY SSF53850 91 291 1.4E-36 T 12-10-2018 VAPA_1c34020 5eea57c37793b69b9f19a6b050bcc186 301 Gene3D G3DSA:3.40.190.10 163 264 3.8E-29 T 12-10-2018 VAPA_1c34020 5eea57c37793b69b9f19a6b050bcc186 301 Gene3D G3DSA:3.40.190.10 92 277 3.8E-29 T 12-10-2018 VAPA_1c34020 5eea57c37793b69b9f19a6b050bcc186 301 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 1.1E-16 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c34020 5eea57c37793b69b9f19a6b050bcc186 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 8.2E-9 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c34020 5eea57c37793b69b9f19a6b050bcc186 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 8.2E-9 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c34020 5eea57c37793b69b9f19a6b050bcc186 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 8.2E-9 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c12600 afd490201981ce3b01da58a83396cb16 478 SUPERFAMILY SSF81648 359 467 7.59E-15 T 12-10-2018 IPR036150 Cytochrome b/b6, C-terminal domain superfamily GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 VAPA_1c12600 afd490201981ce3b01da58a83396cb16 478 Pfam PF00032 Cytochrome b(C-terminal)/b6/petD 290 334 4.0E-14 T 12-10-2018 IPR005798 Cytochrome b/b6, C-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 VAPA_1c12600 afd490201981ce3b01da58a83396cb16 478 Pfam PF00032 Cytochrome b(C-terminal)/b6/petD 359 451 3.7E-23 T 12-10-2018 IPR005798 Cytochrome b/b6, C-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 VAPA_1c12600 afd490201981ce3b01da58a83396cb16 478 SUPERFAMILY SSF81342 19 292 2.83E-96 T 12-10-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 VAPA_1c12600 afd490201981ce3b01da58a83396cb16 478 Pfam PF00033 Cytochrome b/b6/petB 38 224 1.9E-67 T 12-10-2018 IPR005797 Cytochrome b/b6, N-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 VAPA_1c12600 afd490201981ce3b01da58a83396cb16 478 PIRSF PIRSF038885 11 345 5.0E-134 T 12-10-2018 IPR030689 Cytochrome b GO:0006122|GO:0008121|GO:0009055|GO:0045275 Reactome: R-HSA-611105 VAPA_1c12600 afd490201981ce3b01da58a83396cb16 478 PIRSF PIRSF038885 335 478 4.9E-19 T 12-10-2018 IPR030689 Cytochrome b GO:0006122|GO:0008121|GO:0009055|GO:0045275 Reactome: R-HSA-611105 VAPA_1c12600 afd490201981ce3b01da58a83396cb16 478 SUPERFAMILY SSF81648 294 334 7.19E-10 T 12-10-2018 IPR036150 Cytochrome b/b6, C-terminal domain superfamily GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 VAPA_1c12600 afd490201981ce3b01da58a83396cb16 478 Gene3D G3DSA:1.20.810.10 8 478 4.2E-149 T 12-10-2018 IPR027387 Cytochrome b/b6-like domain superfamily Reactome: R-HSA-611105 VAPA_2c00730 05b070d025bb90b22e7b742ac5c6e93e 326 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 51 323 2.2E-35 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_2c00730 05b070d025bb90b22e7b742ac5c6e93e 326 Gene3D G3DSA:3.40.190.10 130 252 2.3E-68 T 12-10-2018 VAPA_2c00730 05b070d025bb90b22e7b742ac5c6e93e 326 Gene3D G3DSA:3.40.190.150 36 317 2.3E-68 T 12-10-2018 VAPA_2c00730 05b070d025bb90b22e7b742ac5c6e93e 326 PIRSF PIRSF017082 1 326 2.1E-52 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c28110 cb43175f78a975af28fd7c17d9276da7 494 Pfam PF14520 Helix-hairpin-helix domain 433 487 1.1E-8 T 12-10-2018 VAPA_1c28110 cb43175f78a975af28fd7c17d9276da7 494 Gene3D G3DSA:3.30.300.20 201 279 2.3E-30 T 12-10-2018 IPR015946 K homology domain-like, alpha/beta VAPA_1c28110 cb43175f78a975af28fd7c17d9276da7 494 SUPERFAMILY SSF47794 359 418 2.04E-15 T 12-10-2018 IPR010995 DNA repair Rad51/transcription factor NusA, alpha-helical GO:0000166 Reactome: R-HSA-912446 VAPA_1c28110 cb43175f78a975af28fd7c17d9276da7 494 SUPERFAMILY SSF47794 429 492 3.45E-14 T 12-10-2018 IPR010995 DNA repair Rad51/transcription factor NusA, alpha-helical GO:0000166 Reactome: R-HSA-912446 VAPA_1c28110 cb43175f78a975af28fd7c17d9276da7 494 Gene3D G3DSA:1.10.150.20 354 423 5.6E-28 T 12-10-2018 VAPA_1c28110 cb43175f78a975af28fd7c17d9276da7 494 SUPERFAMILY SSF54814 281 345 8.5E-16 T 12-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 VAPA_1c28110 cb43175f78a975af28fd7c17d9276da7 494 Hamap MF_00945_B Transcription termination/antitermination protein NusA [nusA]. 2 412 28.474 T 12-10-2018 IPR030842 Transcription termination/antitermination protein NusA, bacterial GO:0006353|GO:0031564 VAPA_1c28110 cb43175f78a975af28fd7c17d9276da7 494 TIGRFAM TIGR01954 nusA_Cterm_rpt: transcription termination factor NusA, C-terminal duplication 441 489 4.0E-14 T 12-10-2018 IPR010214 Transcription termination factor NusA, C-terminal duplication VAPA_1c28110 cb43175f78a975af28fd7c17d9276da7 494 TIGRFAM TIGR01954 nusA_Cterm_rpt: transcription termination factor NusA, C-terminal duplication 367 416 7.5E-19 T 12-10-2018 IPR010214 Transcription termination factor NusA, C-terminal duplication VAPA_1c28110 cb43175f78a975af28fd7c17d9276da7 494 SMART SM00322 303 381 5.2E-4 T 12-10-2018 IPR004087 K Homology domain GO:0003676 VAPA_1c28110 cb43175f78a975af28fd7c17d9276da7 494 Gene3D G3DSA:3.30.300.20 280 348 6.1E-26 T 12-10-2018 IPR015946 K homology domain-like, alpha/beta VAPA_1c28110 cb43175f78a975af28fd7c17d9276da7 494 Pfam PF00575 S1 RNA binding domain 139 194 8.8E-6 T 12-10-2018 IPR003029 S1 domain GO:0003676 VAPA_1c28110 cb43175f78a975af28fd7c17d9276da7 494 Gene3D G3DSA:3.30.1480.10 1 132 1.1E-38 T 12-10-2018 IPR036555 NusA, N-terminal domain superfamily GO:0003700|GO:0031554 VAPA_1c28110 cb43175f78a975af28fd7c17d9276da7 494 Pfam PF08529 NusA N-terminal domain 4 127 6.3E-33 T 12-10-2018 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 VAPA_1c28110 cb43175f78a975af28fd7c17d9276da7 494 TIGRFAM TIGR01953 NusA: transcription termination factor NusA 5 343 2.9E-119 T 12-10-2018 IPR010213 Transcription termination factor NusA GO:0003723 VAPA_1c28110 cb43175f78a975af28fd7c17d9276da7 494 Gene3D G3DSA:1.10.150.20 431 489 8.9E-20 T 12-10-2018 VAPA_1c28110 cb43175f78a975af28fd7c17d9276da7 494 SMART SM00316 136 202 1.3E-6 T 12-10-2018 IPR022967 RNA-binding domain, S1 VAPA_1c28110 cb43175f78a975af28fd7c17d9276da7 494 Gene3D G3DSA:2.40.50.140 137 200 8.4E-16 T 12-10-2018 VAPA_1c28110 cb43175f78a975af28fd7c17d9276da7 494 SUPERFAMILY SSF69705 1 128 1.01E-36 T 12-10-2018 IPR036555 NusA, N-terminal domain superfamily GO:0003700|GO:0031554 VAPA_1c28110 cb43175f78a975af28fd7c17d9276da7 494 SUPERFAMILY SSF50249 136 201 2.14E-13 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold VAPA_1c28110 cb43175f78a975af28fd7c17d9276da7 494 Pfam PF13184 NusA-like KH domain 232 299 1.1E-26 T 12-10-2018 IPR025249 KH domain, NusA-like GO:0003723 VAPA_1c28110 cb43175f78a975af28fd7c17d9276da7 494 SUPERFAMILY SSF54814 203 280 5.62E-29 T 12-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 VAPA_1c27540 caa904f48844338d74a5c9c4a63c679f 315 Gene3D G3DSA:3.30.70.1230 3 176 8.9E-40 T 12-10-2018 IPR029787 Nucleotide cyclase VAPA_1c27540 caa904f48844338d74a5c9c4a63c679f 315 SMART SM00240 212 261 0.002 T 12-10-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 VAPA_1c27540 caa904f48844338d74a5c9c4a63c679f 315 SUPERFAMILY SSF55073 5 174 6.44E-36 T 12-10-2018 IPR029787 Nucleotide cyclase VAPA_1c27540 caa904f48844338d74a5c9c4a63c679f 315 Pfam PF00211 Adenylate and Guanylate cyclase catalytic domain 6 162 2.7E-12 T 12-10-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 VAPA_1c27540 caa904f48844338d74a5c9c4a63c679f 315 Pfam PF00498 FHA domain 214 259 2.1E-8 T 12-10-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 VAPA_1c27540 caa904f48844338d74a5c9c4a63c679f 315 SUPERFAMILY SSF49879 204 287 4.02E-14 T 12-10-2018 IPR008984 SMAD/FHA domain superfamily GO:0005515 VAPA_1c27540 caa904f48844338d74a5c9c4a63c679f 315 Gene3D G3DSA:2.60.200.20 193 294 7.4E-14 T 12-10-2018 VAPA_1c10520 3e614ba70b4de77f1a06372d5c34fd65 210 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 2 70 6.6E-10 T 12-10-2018 IPR000477 Reverse transcriptase domain VAPA_1c10520 3e614ba70b4de77f1a06372d5c34fd65 210 Pfam PF08388 Group II intron, maturase-specific domain 89 157 2.1E-14 T 12-10-2018 IPR013597 Group II intron, maturase-specific VAPA_1c10520 3e614ba70b4de77f1a06372d5c34fd65 210 SUPERFAMILY SSF56672 9 148 6.67E-10 T 12-10-2018 VAPA_1c28530 b1c973983c11881ad13fa76257f464ef 172 Hamap MF_02204 Peptidoglycan-associated lipoprotein [pal]. 1 170 30.543 T 12-10-2018 IPR039001 Peptidoglycan-associated lipoprotein GO:0009279|GO:0051301 VAPA_1c28530 b1c973983c11881ad13fa76257f464ef 172 TIGRFAM TIGR02802 Pal_lipo: peptidoglycan-associated lipoprotein 68 170 1.8E-42 T 12-10-2018 IPR014169 Peptidoglycan-associated lipoprotein, C-terminal GO:0009279 VAPA_1c28530 b1c973983c11881ad13fa76257f464ef 172 PRINTS PR01021 OMPA domain signature 100 115 7.7E-17 T 12-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 VAPA_1c28530 b1c973983c11881ad13fa76257f464ef 172 PRINTS PR01021 OMPA domain signature 115 131 7.7E-17 T 12-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 VAPA_1c28530 b1c973983c11881ad13fa76257f464ef 172 PRINTS PR01021 OMPA domain signature 70 92 7.7E-17 T 12-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 VAPA_1c28530 b1c973983c11881ad13fa76257f464ef 172 Gene3D G3DSA:3.30.1330.60 55 171 4.8E-38 T 12-10-2018 IPR036737 OmpA-like domain superfamily VAPA_1c28530 b1c973983c11881ad13fa76257f464ef 172 SUPERFAMILY SSF103088 58 169 1.31E-34 T 12-10-2018 IPR036737 OmpA-like domain superfamily VAPA_1c28530 b1c973983c11881ad13fa76257f464ef 172 Pfam PF00691 OmpA family 69 164 1.6E-22 T 12-10-2018 IPR006665 OmpA-like domain VAPA_1c15190 50ebc29e56c4deacb7e840077310d792 107 Gene3D G3DSA:1.10.150.250 10 98 1.0E-18 T 12-10-2018 IPR036714 Flavinator of succinate dehydrogenase superfamily VAPA_1c15190 50ebc29e56c4deacb7e840077310d792 107 SUPERFAMILY SSF109910 12 81 4.97E-17 T 12-10-2018 IPR036714 Flavinator of succinate dehydrogenase superfamily VAPA_1c15190 50ebc29e56c4deacb7e840077310d792 107 Pfam PF03937 Flavinator of succinate dehydrogenase 17 87 5.5E-21 T 12-10-2018 IPR005631 Flavinator of succinate dehydrogenase VAPA_1c52800 865ab3b7bbc776635c991ce4fc95646f 476 Pfam PF02113 D-Ala-D-Ala carboxypeptidase 3 (S13) family 35 474 1.1E-73 T 12-10-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 VAPA_1c52800 865ab3b7bbc776635c991ce4fc95646f 476 TIGRFAM TIGR00666 PBP4: D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase 68 455 1.8E-52 T 12-10-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 VAPA_1c52800 865ab3b7bbc776635c991ce4fc95646f 476 Gene3D G3DSA:3.50.80.20 96 188 1.7E-19 T 12-10-2018 VAPA_1c52800 865ab3b7bbc776635c991ce4fc95646f 476 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 372 386 5.2E-18 T 12-10-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 VAPA_1c52800 865ab3b7bbc776635c991ce4fc95646f 476 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 357 371 5.2E-18 T 12-10-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 VAPA_1c52800 865ab3b7bbc776635c991ce4fc95646f 476 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 432 445 5.2E-18 T 12-10-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 VAPA_1c52800 865ab3b7bbc776635c991ce4fc95646f 476 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 299 321 5.2E-18 T 12-10-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 VAPA_1c52800 865ab3b7bbc776635c991ce4fc95646f 476 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 72 91 5.2E-18 T 12-10-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 VAPA_1c52800 865ab3b7bbc776635c991ce4fc95646f 476 SUPERFAMILY SSF56601 31 474 4.2E-93 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like VAPA_1c52800 865ab3b7bbc776635c991ce4fc95646f 476 Gene3D G3DSA:3.40.710.10 285 470 6.8E-53 T 12-10-2018 VAPA_1c45760 a537b4d1dcfd7f478de1968c29c3f94b 617 SUPERFAMILY SSF56801 39 597 4.19E-81 T 12-10-2018 VAPA_1c45760 a537b4d1dcfd7f478de1968c29c3f94b 617 Gene3D G3DSA:3.40.50.12780 30 463 3.5E-68 T 12-10-2018 VAPA_1c45760 a537b4d1dcfd7f478de1968c29c3f94b 617 Pfam PF00501 AMP-binding enzyme 46 461 4.0E-60 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 VAPA_1c08360 e4806e8508620ffdaf648fe193d9e073 1474 Pfam PF08241 Methyltransferase domain 1296 1348 7.1E-11 T 12-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 VAPA_1c08360 e4806e8508620ffdaf648fe193d9e073 1474 Gene3D G3DSA:3.40.50.2000 560 882 7.0E-20 T 12-10-2018 VAPA_1c08360 e4806e8508620ffdaf648fe193d9e073 1474 Gene3D G3DSA:3.40.50.150 40 200 8.8E-20 T 12-10-2018 VAPA_1c08360 e4806e8508620ffdaf648fe193d9e073 1474 Pfam PF13692 Glycosyl transferases group 1 715 862 2.1E-8 T 12-10-2018 VAPA_1c08360 e4806e8508620ffdaf648fe193d9e073 1474 Gene3D G3DSA:3.90.550.10 915 1169 3.6E-46 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases VAPA_1c08360 e4806e8508620ffdaf648fe193d9e073 1474 SUPERFAMILY SSF53335 1301 1387 4.3E-16 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase VAPA_1c08360 e4806e8508620ffdaf648fe193d9e073 1474 SUPERFAMILY SSF53448 941 1148 3.38E-43 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases VAPA_1c08360 e4806e8508620ffdaf648fe193d9e073 1474 SUPERFAMILY SSF53335 39 211 5.81E-17 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase VAPA_1c08360 e4806e8508620ffdaf648fe193d9e073 1474 Pfam PF13578 Methyltransferase domain 59 175 2.0E-25 T 12-10-2018 VAPA_1c08360 e4806e8508620ffdaf648fe193d9e073 1474 Pfam PF00535 Glycosyl transferase family 2 943 1066 4.3E-24 T 12-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 VAPA_1c08360 e4806e8508620ffdaf648fe193d9e073 1474 Gene3D G3DSA:3.40.50.2000 690 877 7.0E-20 T 12-10-2018 VAPA_1c08360 e4806e8508620ffdaf648fe193d9e073 1474 SUPERFAMILY SSF53756 583 897 3.33E-25 T 12-10-2018 VAPA_1c08360 e4806e8508620ffdaf648fe193d9e073 1474 SUPERFAMILY SSF158997 1198 1242 2.75E-5 T 12-10-2018 VAPA_1c08360 e4806e8508620ffdaf648fe193d9e073 1474 Gene3D G3DSA:3.40.50.150 1260 1424 1.9E-17 T 12-10-2018 VAPA_1c37170 157294ab2b8eada4dff40eed25488962 474 Gene3D G3DSA:1.10.10.10 14 106 1.1E-20 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c37170 157294ab2b8eada4dff40eed25488962 474 SUPERFAMILY SSF53383 110 464 1.24E-71 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase VAPA_1c37170 157294ab2b8eada4dff40eed25488962 474 Gene3D G3DSA:3.40.640.10 149 365 1.1E-72 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 VAPA_1c37170 157294ab2b8eada4dff40eed25488962 474 Gene3D G3DSA:3.90.1150.10 113 458 1.1E-72 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 VAPA_1c37170 157294ab2b8eada4dff40eed25488962 474 Pfam PF00392 Bacterial regulatory proteins, gntR family 18 80 4.9E-17 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_1c37170 157294ab2b8eada4dff40eed25488962 474 SMART SM00345 21 80 2.9E-17 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_1c37170 157294ab2b8eada4dff40eed25488962 474 Pfam PF00155 Aminotransferase class I and II 143 451 3.9E-29 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 VAPA_1c37170 157294ab2b8eada4dff40eed25488962 474 SUPERFAMILY SSF46785 11 90 7.77E-21 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c34310 32167ae6c783e3b387be83eae9e3b70f 307 SUPERFAMILY SSF53223 3 108 2.65E-15 T 12-10-2018 VAPA_1c34310 32167ae6c783e3b387be83eae9e3b70f 307 Gene3D G3DSA:3.40.50.720 111 254 6.9E-50 T 12-10-2018 VAPA_1c34310 32167ae6c783e3b387be83eae9e3b70f 307 Gene3D G3DSA:3.40.50.10860 11 110 6.9E-50 T 12-10-2018 VAPA_1c34310 32167ae6c783e3b387be83eae9e3b70f 307 SUPERFAMILY SSF51735 111 259 1.1E-23 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c34310 32167ae6c783e3b387be83eae9e3b70f 307 Pfam PF08501 Shikimate dehydrogenase substrate binding domain 16 97 7.9E-10 T 12-10-2018 IPR013708 Shikimate dehydrogenase substrate binding, N-terminal GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 VAPA_1c36210 7ba636af8d79d45de409f2c13e310aae 261 SUPERFAMILY SSF51351 6 258 5.37E-88 T 12-10-2018 IPR035990 Triosephosphate isomerase superfamily GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 VAPA_1c36210 7ba636af8d79d45de409f2c13e310aae 261 Gene3D G3DSA:3.20.20.70 1 261 4.1E-100 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 VAPA_1c36210 7ba636af8d79d45de409f2c13e310aae 261 Pfam PF00121 Triosephosphate isomerase 13 256 1.9E-87 T 12-10-2018 IPR000652 Triosephosphate isomerase GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 VAPA_1c36210 7ba636af8d79d45de409f2c13e310aae 261 Hamap MF_00147_B Triosephosphate isomerase [tpiA]. 11 258 59.798 T 12-10-2018 IPR022896 Triosephosphate isomerase, bacterial/eukaryotic GO:0004807|GO:0006096 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 VAPA_1c36210 7ba636af8d79d45de409f2c13e310aae 261 ProSitePatterns PS00171 Triosephosphate isomerase active site. 175 185 - T 12-10-2018 IPR020861 Triosephosphate isomerase, active site GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 VAPA_1c36210 7ba636af8d79d45de409f2c13e310aae 261 TIGRFAM TIGR00419 tim: triose-phosphate isomerase 14 249 4.7E-64 T 12-10-2018 IPR000652 Triosephosphate isomerase GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 VAPA_1c32370 97dadee666dea67291675913de72f557 383 Gene3D G3DSA:3.30.565.10 222 373 1.7E-31 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_1c32370 97dadee666dea67291675913de72f557 383 SMART SM00388 150 215 1.2E-11 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 VAPA_1c32370 97dadee666dea67291675913de72f557 383 Gene3D G3DSA:1.10.287.130 137 213 7.2E-11 T 12-10-2018 VAPA_1c32370 97dadee666dea67291675913de72f557 383 SMART SM00387 259 375 1.3E-25 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase VAPA_1c32370 97dadee666dea67291675913de72f557 383 SUPERFAMILY SSF55874 205 373 1.1E-32 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_1c32370 97dadee666dea67291675913de72f557 383 SUPERFAMILY SSF47384 147 213 2.16E-10 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 VAPA_1c32370 97dadee666dea67291675913de72f557 383 Pfam PF14361 RsbT co-antagonist protein rsbRD N-terminal domain 3 108 5.6E-6 T 12-10-2018 IPR025751 RsbT co-antagonist protein RsbRD, N-terminal domain VAPA_1c32370 97dadee666dea67291675913de72f557 383 Pfam PF00512 His Kinase A (phospho-acceptor) domain 150 212 2.1E-10 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 VAPA_1c32370 97dadee666dea67291675913de72f557 383 PRINTS PR00344 Bacterial sensor protein C-terminal signature 296 310 3.7E-9 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c32370 97dadee666dea67291675913de72f557 383 PRINTS PR00344 Bacterial sensor protein C-terminal signature 335 353 3.7E-9 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c32370 97dadee666dea67291675913de72f557 383 PRINTS PR00344 Bacterial sensor protein C-terminal signature 359 372 3.7E-9 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c32370 97dadee666dea67291675913de72f557 383 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 260 373 3.9E-19 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase VAPA_1c36290 9ec9adc458bd4283786a7acc535b8b27 354 Hamap MF_01445 tRNA N6-adenosine threonylcarbamoyltransferase [tsaD]. 1 339 62.402 T 12-10-2018 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 VAPA_1c36290 9ec9adc458bd4283786a7acc535b8b27 354 ProSitePatterns PS01016 Glycoprotease family signature. 100 120 - T 12-10-2018 IPR017860 Peptidase M22, conserved site Reactome: R-HSA-6782315 VAPA_1c36290 9ec9adc458bd4283786a7acc535b8b27 354 Gene3D G3DSA:3.30.420.40 133 298 1.1E-121 T 12-10-2018 VAPA_1c36290 9ec9adc458bd4283786a7acc535b8b27 354 TIGRFAM TIGR00329 gcp_kae1: metallohydrolase, glycoprotease/Kae1 family 4 311 1.1E-108 T 12-10-2018 IPR017861 Kae1/TsaD family VAPA_1c36290 9ec9adc458bd4283786a7acc535b8b27 354 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 4 17 3.3E-49 T 12-10-2018 IPR017861 Kae1/TsaD family VAPA_1c36290 9ec9adc458bd4283786a7acc535b8b27 354 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 135 147 3.3E-49 T 12-10-2018 IPR017861 Kae1/TsaD family VAPA_1c36290 9ec9adc458bd4283786a7acc535b8b27 354 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 80 100 3.3E-49 T 12-10-2018 IPR017861 Kae1/TsaD family VAPA_1c36290 9ec9adc458bd4283786a7acc535b8b27 354 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 101 120 3.3E-49 T 12-10-2018 IPR017861 Kae1/TsaD family VAPA_1c36290 9ec9adc458bd4283786a7acc535b8b27 354 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 158 179 3.3E-49 T 12-10-2018 IPR017861 Kae1/TsaD family VAPA_1c36290 9ec9adc458bd4283786a7acc535b8b27 354 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 268 277 3.3E-49 T 12-10-2018 IPR017861 Kae1/TsaD family VAPA_1c36290 9ec9adc458bd4283786a7acc535b8b27 354 TIGRFAM TIGR03723 T6A_TsaD_YgjD: tRNA threonylcarbamoyl adenosine modification protein TsaD 4 318 2.7E-129 T 12-10-2018 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 VAPA_1c36290 9ec9adc458bd4283786a7acc535b8b27 354 SUPERFAMILY SSF53067 3 125 6.02E-27 T 12-10-2018 VAPA_1c36290 9ec9adc458bd4283786a7acc535b8b27 354 Gene3D G3DSA:3.30.420.40 4 320 1.1E-121 T 12-10-2018 VAPA_1c36290 9ec9adc458bd4283786a7acc535b8b27 354 Pfam PF00814 Glycoprotease family 28 311 1.2E-97 T 12-10-2018 IPR000905 Gcp-like domain VAPA_1c36290 9ec9adc458bd4283786a7acc535b8b27 354 SUPERFAMILY SSF53067 105 313 2.33E-42 T 12-10-2018 VAPA_1c04950 9cae52d0d7b913cda7006d050414dd58 723 SUPERFAMILY SSF81296 118 224 8.75E-32 T 12-10-2018 IPR014756 Immunoglobulin E-set VAPA_1c04950 9cae52d0d7b913cda7006d050414dd58 723 SUPERFAMILY SSF51445 231 617 1.86E-115 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily VAPA_1c04950 9cae52d0d7b913cda7006d050414dd58 723 Gene3D G3DSA:2.60.40.1180 622 722 7.1E-36 T 12-10-2018 IPR013780 Glycosyl hydrolase, all-beta VAPA_1c04950 9cae52d0d7b913cda7006d050414dd58 723 Gene3D G3DSA:2.60.40.10 4 222 8.2E-71 T 12-10-2018 IPR013783 Immunoglobulin-like fold VAPA_1c04950 9cae52d0d7b913cda7006d050414dd58 723 Hamap MF_00685 1,4-alpha-glucan branching enzyme GlgB [glgB]. 102 723 43.641 T 12-10-2018 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|MetaCyc: PWY-7900 VAPA_1c04950 9cae52d0d7b913cda7006d050414dd58 723 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 126 208 2.4E-21 T 12-10-2018 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 VAPA_1c04950 9cae52d0d7b913cda7006d050414dd58 723 Pfam PF02806 Alpha amylase, C-terminal all-beta domain 626 721 3.6E-21 T 12-10-2018 IPR006048 Alpha-amylase/branching enzyme, C-terminal all beta GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|MetaCyc: PWY-7900 VAPA_1c04950 9cae52d0d7b913cda7006d050414dd58 723 SUPERFAMILY SSF81296 18 116 3.32E-16 T 12-10-2018 IPR014756 Immunoglobulin E-set VAPA_1c04950 9cae52d0d7b913cda7006d050414dd58 723 SMART SM00642 248 598 5.2E-8 T 12-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 VAPA_1c04950 9cae52d0d7b913cda7006d050414dd58 723 TIGRFAM TIGR01515 branching_enzym: 1,4-alpha-glucan branching enzyme 110 719 7.7E-290 T 12-10-2018 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|MetaCyc: PWY-7900 VAPA_1c04950 9cae52d0d7b913cda7006d050414dd58 723 Pfam PF00128 Alpha amylase, catalytic domain 274 344 5.5E-8 T 12-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 VAPA_1c04950 9cae52d0d7b913cda7006d050414dd58 723 PIRSF PIRSF000463 8 723 1.0E-278 T 12-10-2018 IPR037439 1,4-alpha-glucan-branching enzyme GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|MetaCyc: PWY-7900|Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 VAPA_1c04950 9cae52d0d7b913cda7006d050414dd58 723 SUPERFAMILY SSF51011 622 722 2.16E-32 T 12-10-2018 VAPA_1c04950 9cae52d0d7b913cda7006d050414dd58 723 Gene3D G3DSA:3.20.20.80 232 610 5.1E-168 T 12-10-2018 VAPA_1c33660 f8d741b99e1a3b25c54d7b19982a6f8d 507 SUPERFAMILY SSF53720 8 492 1.57E-144 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 VAPA_1c33660 f8d741b99e1a3b25c54d7b19982a6f8d 507 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 284 295 - T 12-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 VAPA_1c33660 f8d741b99e1a3b25c54d7b19982a6f8d 507 Pfam PF00171 Aldehyde dehydrogenase family 22 486 2.2E-140 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 VAPA_1c33660 f8d741b99e1a3b25c54d7b19982a6f8d 507 Gene3D G3DSA:3.40.309.10 259 459 8.4E-146 T 12-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 VAPA_1c33660 f8d741b99e1a3b25c54d7b19982a6f8d 507 TIGRFAM TIGR01722 MMSDH: methylmalonate-semialdehyde dehydrogenase (acylating) 14 490 5.0E-222 T 12-10-2018 IPR010061 Methylmalonate-semialdehyde dehydrogenase GO:0004491|GO:0055114 KEGG: 00280+1.2.1.27|KEGG: 00640+1.2.1.27|MetaCyc: PWY-5642|Reactome: R-HSA-70895 VAPA_1c33660 f8d741b99e1a3b25c54d7b19982a6f8d 507 Gene3D G3DSA:3.40.605.10 34 467 8.4E-146 T 12-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 VAPA_1c07400 d0ea8ccfc958b9c8037c2b32bcab8e31 177 SUPERFAMILY SSF160369 4 159 4.32E-49 T 12-10-2018 VAPA_1c07400 d0ea8ccfc958b9c8037c2b32bcab8e31 177 Pfam PF00466 Ribosomal protein L10 4 100 5.8E-23 T 12-10-2018 IPR001790 Ribosomal protein L10P GO:0005622|GO:0042254 VAPA_1c07400 d0ea8ccfc958b9c8037c2b32bcab8e31 177 ProSitePatterns PS01109 Ribosomal protein L10 signature. 8 42 - T 12-10-2018 IPR002363 Ribosomal protein L10, eubacterial, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 VAPA_1c07400 d0ea8ccfc958b9c8037c2b32bcab8e31 177 Hamap MF_00362 50S ribosomal protein L10 [rplJ]. 3 160 26.601 T 12-10-2018 IPR022973 Ribosomal protein L10 VAPA_1c07400 d0ea8ccfc958b9c8037c2b32bcab8e31 177 Gene3D G3DSA:3.30.70.1730 3 132 6.0E-35 T 12-10-2018 VAPA_1c21060 f2a4e5fd829f70f44c5b1c25303377af 145 Gene3D G3DSA:2.60.40.790 3 145 8.4E-25 T 12-10-2018 IPR008978 HSP20-like chaperone VAPA_1c21060 f2a4e5fd829f70f44c5b1c25303377af 145 SUPERFAMILY SSF49764 22 144 3.84E-27 T 12-10-2018 IPR008978 HSP20-like chaperone VAPA_1c21060 f2a4e5fd829f70f44c5b1c25303377af 145 Pfam PF00011 Hsp20/alpha crystallin family 49 145 5.4E-18 T 12-10-2018 IPR002068 Alpha crystallin/Hsp20 domain VAPA_1c23740 8b56921ddae35259fe1ab8315f468ed2 464 Gene3D G3DSA:3.30.479.30 186 298 3.5E-18 T 12-10-2018 VAPA_1c23740 8b56921ddae35259fe1ab8315f468ed2 464 Pfam PF01145 SPFH domain / Band 7 family 136 322 4.9E-25 T 12-10-2018 IPR001107 Band 7 domain VAPA_1c23740 8b56921ddae35259fe1ab8315f468ed2 464 SUPERFAMILY SSF117892 194 314 4.32E-20 T 12-10-2018 IPR036013 Band 7/SPFH domain superfamily VAPA_1c23740 8b56921ddae35259fe1ab8315f468ed2 464 Pfam PF12221 Bacterial membrane protein N terminal 14 91 3.7E-7 T 12-10-2018 IPR020980 Menbrane protein HflK, N-terminal VAPA_1c23740 8b56921ddae35259fe1ab8315f468ed2 464 TIGRFAM TIGR01933 hflK: HflK protein 134 409 2.8E-89 T 12-10-2018 IPR010201 HflK GO:0016021 VAPA_1c23740 8b56921ddae35259fe1ab8315f468ed2 464 SMART SM00244 132 307 1.6E-25 T 12-10-2018 IPR001107 Band 7 domain VAPA_1c27620 6c5531b6d9e608fdd2cb84e96c569af9 208 Pfam PF00072 Response regulator receiver domain 10 119 1.5E-24 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_1c27620 6c5531b6d9e608fdd2cb84e96c569af9 208 SUPERFAMILY SSF52172 9 169 8.11E-32 T 12-10-2018 IPR011006 CheY-like superfamily VAPA_1c27620 6c5531b6d9e608fdd2cb84e96c569af9 208 Gene3D G3DSA:1.10.10.10 136 202 1.5E-23 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c27620 6c5531b6d9e608fdd2cb84e96c569af9 208 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 176 188 4.0E-15 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_1c27620 6c5531b6d9e608fdd2cb84e96c569af9 208 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 146 160 4.0E-15 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_1c27620 6c5531b6d9e608fdd2cb84e96c569af9 208 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 160 176 4.0E-15 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_1c27620 6c5531b6d9e608fdd2cb84e96c569af9 208 ProSitePatterns PS00622 LuxR-type HTH domain signature. 160 187 - T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_1c27620 6c5531b6d9e608fdd2cb84e96c569af9 208 SMART SM00421 143 200 3.7E-23 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_1c27620 6c5531b6d9e608fdd2cb84e96c569af9 208 Gene3D G3DSA:3.40.50.2300 4 135 9.1E-39 T 12-10-2018 VAPA_1c27620 6c5531b6d9e608fdd2cb84e96c569af9 208 Pfam PF00196 Bacterial regulatory proteins, luxR family 145 198 4.3E-21 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_1c27620 6c5531b6d9e608fdd2cb84e96c569af9 208 SMART SM00448 8 119 2.5E-25 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_2c10130 fb011c2becea3a2c6994c85f9dcce2aa 305 SUPERFAMILY SSF46785 1 112 2.46E-18 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_2c10130 fb011c2becea3a2c6994c85f9dcce2aa 305 Gene3D G3DSA:3.40.190.10 92 294 6.3E-52 T 12-10-2018 VAPA_2c10130 fb011c2becea3a2c6994c85f9dcce2aa 305 Gene3D G3DSA:3.40.190.10 162 267 6.3E-52 T 12-10-2018 VAPA_2c10130 fb011c2becea3a2c6994c85f9dcce2aa 305 Gene3D G3DSA:1.10.10.10 2 89 1.3E-18 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_2c10130 fb011c2becea3a2c6994c85f9dcce2aa 305 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 63 2.1E-15 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_2c10130 fb011c2becea3a2c6994c85f9dcce2aa 305 SUPERFAMILY SSF53850 90 299 1.71E-35 T 12-10-2018 VAPA_2c10130 fb011c2becea3a2c6994c85f9dcce2aa 305 Pfam PF03466 LysR substrate binding domain 89 296 4.8E-34 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_1c36970 f12680d10d712e6ad4daf63cde09068b 1107 Gene3D G3DSA:3.30.450.350 77 271 2.7E-24 T 12-10-2018 VAPA_1c36970 f12680d10d712e6ad4daf63cde09068b 1107 Pfam PF03924 CHASE domain 76 260 1.6E-37 T 12-10-2018 IPR006189 CHASE domain VAPA_1c36970 f12680d10d712e6ad4daf63cde09068b 1107 SUPERFAMILY SSF141868 847 1097 8.37E-94 T 12-10-2018 IPR035919 EAL domain superfamily VAPA_1c36970 f12680d10d712e6ad4daf63cde09068b 1107 Gene3D G3DSA:3.30.450.40 490 667 9.2E-11 T 12-10-2018 IPR029016 GAF-like domain superfamily VAPA_1c36970 f12680d10d712e6ad4daf63cde09068b 1107 SMART SM00052 842 1088 1.6E-120 T 12-10-2018 IPR001633 EAL domain VAPA_1c36970 f12680d10d712e6ad4daf63cde09068b 1107 Pfam PF00990 Diguanylate cyclase, GGDEF domain 671 828 1.9E-51 T 12-10-2018 IPR000160 GGDEF domain VAPA_1c36970 f12680d10d712e6ad4daf63cde09068b 1107 SUPERFAMILY SSF55781 516 668 4.91E-9 T 12-10-2018 VAPA_1c36970 f12680d10d712e6ad4daf63cde09068b 1107 SMART SM00065 514 668 0.0068 T 12-10-2018 IPR003018 GAF domain GO:0005515 VAPA_1c36970 f12680d10d712e6ad4daf63cde09068b 1107 Pfam PF00563 EAL domain 848 1083 1.7E-79 T 12-10-2018 IPR001633 EAL domain VAPA_1c36970 f12680d10d712e6ad4daf63cde09068b 1107 Gene3D G3DSA:3.20.20.450 846 1097 1.4E-105 T 12-10-2018 IPR035919 EAL domain superfamily VAPA_1c36970 f12680d10d712e6ad4daf63cde09068b 1107 Gene3D G3DSA:3.30.70.270 668 845 2.3E-62 T 12-10-2018 VAPA_1c36970 f12680d10d712e6ad4daf63cde09068b 1107 SUPERFAMILY SSF55073 676 832 5.41E-51 T 12-10-2018 IPR029787 Nucleotide cyclase VAPA_1c36970 f12680d10d712e6ad4daf63cde09068b 1107 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 667 830 1.4E-48 T 12-10-2018 IPR000160 GGDEF domain VAPA_1c36970 f12680d10d712e6ad4daf63cde09068b 1107 SMART SM00267 660 832 1.8E-68 T 12-10-2018 IPR000160 GGDEF domain VAPA_1c36970 f12680d10d712e6ad4daf63cde09068b 1107 SUPERFAMILY SSF55785 369 490 1.66E-12 T 12-10-2018 IPR035965 PAS domain superfamily VAPA_1c36970 f12680d10d712e6ad4daf63cde09068b 1107 SMART SM01079 73 287 1.7E-41 T 12-10-2018 IPR006189 CHASE domain VAPA_1c36970 f12680d10d712e6ad4daf63cde09068b 1107 Gene3D G3DSA:3.30.450.20 371 488 3.6E-17 T 12-10-2018 VAPA_1c31420 4e28cca522be5c20cd64e929362e5261 175 SUPERFAMILY SSF55620 32 147 4.09E-31 T 12-10-2018 VAPA_1c31420 4e28cca522be5c20cd64e929362e5261 175 SMART SM00905 36 146 5.6E-34 T 12-10-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 VAPA_1c31420 4e28cca522be5c20cd64e929362e5261 175 Pfam PF02152 Dihydroneopterin aldolase 36 145 1.9E-24 T 12-10-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 VAPA_1c31420 4e28cca522be5c20cd64e929362e5261 175 Gene3D G3DSA:3.30.1130.10 14 153 3.8E-32 T 12-10-2018 VAPA_1c31420 4e28cca522be5c20cd64e929362e5261 175 TIGRFAM TIGR00526 folB_dom: FolB domain 33 148 3.5E-20 T 12-10-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 VAPA_1c49780 1179fd8273cc5560481af9070e4d607f 157 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 22 33 4.5E-14 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 VAPA_1c49780 1179fd8273cc5560481af9070e4d607f 157 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 33 52 4.5E-14 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 VAPA_1c49780 1179fd8273cc5560481af9070e4d607f 157 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 6 22 4.5E-14 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 VAPA_1c49780 1179fd8273cc5560481af9070e4d607f 157 Pfam PF01037 Lrp/AsnC ligand binding domain 72 146 1.1E-19 T 12-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain VAPA_1c49780 1179fd8273cc5560481af9070e4d607f 157 SMART SM00344 6 115 4.5E-47 T 12-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 VAPA_1c49780 1179fd8273cc5560481af9070e4d607f 157 SUPERFAMILY SSF54909 67 155 3.08E-20 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel VAPA_1c49780 1179fd8273cc5560481af9070e4d607f 157 Pfam PF13412 Winged helix-turn-helix DNA-binding 6 53 2.5E-17 T 12-10-2018 VAPA_1c49780 1179fd8273cc5560481af9070e4d607f 157 Gene3D G3DSA:3.30.70.920 60 143 6.7E-25 T 12-10-2018 VAPA_1c49780 1179fd8273cc5560481af9070e4d607f 157 Gene3D G3DSA:1.10.10.10 2 59 6.4E-22 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c49780 1179fd8273cc5560481af9070e4d607f 157 SUPERFAMILY SSF46785 6 65 6.31E-17 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c38450 33f5ec230fd8bf399e7dd91313b5e9fd 225 SUPERFAMILY SSF48498 96 219 5.19E-23 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily VAPA_1c38450 33f5ec230fd8bf399e7dd91313b5e9fd 225 Gene3D G3DSA:1.10.357.10 72 218 7.8E-21 T 12-10-2018 VAPA_1c38450 33f5ec230fd8bf399e7dd91313b5e9fd 225 Pfam PF16859 Bacterial transcriptional repressor C-terminal 99 189 1.5E-12 T 12-10-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal VAPA_1c38450 33f5ec230fd8bf399e7dd91313b5e9fd 225 SUPERFAMILY SSF46689 15 90 1.25E-19 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 VAPA_1c38450 33f5ec230fd8bf399e7dd91313b5e9fd 225 Pfam PF00440 Bacterial regulatory proteins, tetR family 29 75 4.2E-19 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 VAPA_1c38450 33f5ec230fd8bf399e7dd91313b5e9fd 225 Gene3D G3DSA:1.10.10.60 9 71 1.4E-22 T 12-10-2018 VAPA_1c38450 33f5ec230fd8bf399e7dd91313b5e9fd 225 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 50 73 1.7E-12 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 VAPA_1c38450 33f5ec230fd8bf399e7dd91313b5e9fd 225 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 29 42 1.7E-12 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 VAPA_1c28100 887c2de1e12fdf0ccc5f429c9009129d 984 Hamap MF_00100_B Translation initiation factor IF-2 [infB]. 3 982 17.461 T 12-10-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 VAPA_1c28100 887c2de1e12fdf0ccc5f429c9009129d 984 Pfam PF08364 Bacterial translation initiation factor IF-2 associated region 61 99 6.3E-15 T 12-10-2018 IPR013575 Initiation factor 2 associated domain, bacterial VAPA_1c28100 887c2de1e12fdf0ccc5f429c9009129d 984 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 1 47 7.8E-8 T 12-10-2018 IPR006847 Translation initiation factor IF-2, N-terminal VAPA_1c28100 887c2de1e12fdf0ccc5f429c9009129d 984 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 407 457 2.3E-16 T 12-10-2018 IPR006847 Translation initiation factor IF-2, N-terminal VAPA_1c28100 887c2de1e12fdf0ccc5f429c9009129d 984 Gene3D G3DSA:2.40.30.10 886 983 5.0E-31 T 12-10-2018 VAPA_1c28100 887c2de1e12fdf0ccc5f429c9009129d 984 Gene3D G3DSA:2.40.30.10 656 774 2.6E-41 T 12-10-2018 VAPA_1c28100 887c2de1e12fdf0ccc5f429c9009129d 984 SUPERFAMILY SSF52156 763 891 1.57E-35 T 12-10-2018 IPR036925 Translation initiation factor IF-2, domain 3 superfamily VAPA_1c28100 887c2de1e12fdf0ccc5f429c9009129d 984 SUPERFAMILY SSF50447 657 739 5.61E-26 T 12-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily VAPA_1c28100 887c2de1e12fdf0ccc5f429c9009129d 984 SUPERFAMILY SSF52540 481 654 1.08E-53 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c28100 887c2de1e12fdf0ccc5f429c9009129d 984 Gene3D G3DSA:3.40.50.300 482 655 2.3E-72 T 12-10-2018 VAPA_1c28100 887c2de1e12fdf0ccc5f429c9009129d 984 SUPERFAMILY SSF46955 3 51 1.32E-8 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily VAPA_1c28100 887c2de1e12fdf0ccc5f429c9009129d 984 Pfam PF11987 Translation-initiation factor 2 770 874 1.1E-34 T 12-10-2018 IPR023115 Translation initiation factor IF- 2, domain 3 VAPA_1c28100 887c2de1e12fdf0ccc5f429c9009129d 984 TIGRFAM TIGR00487 IF-2: translation initiation factor IF-2 404 984 6.2E-259 T 12-10-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 VAPA_1c28100 887c2de1e12fdf0ccc5f429c9009129d 984 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 488 642 6.5E-33 T 12-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 VAPA_1c28100 887c2de1e12fdf0ccc5f429c9009129d 984 SUPERFAMILY SSF50447 886 982 9.15E-31 T 12-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily VAPA_1c28100 887c2de1e12fdf0ccc5f429c9009129d 984 Gene3D G3DSA:3.40.50.10050 779 885 5.6E-36 T 12-10-2018 IPR036925 Translation initiation factor IF-2, domain 3 superfamily VAPA_1c28100 887c2de1e12fdf0ccc5f429c9009129d 984 Pfam PF00009 Elongation factor Tu GTP binding domain 489 645 2.1E-36 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 VAPA_1c53150 776829060728cea0a05c88dcdb717fce 256 Gene3D G3DSA:1.10.3720.10 10 255 5.1E-56 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c53150 776829060728cea0a05c88dcdb717fce 256 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 66 251 6.7E-18 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 VAPA_1c53150 776829060728cea0a05c88dcdb717fce 256 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 22 98 6.8E-13 T 12-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 VAPA_1c53150 776829060728cea0a05c88dcdb717fce 256 SUPERFAMILY SSF161098 21 236 9.16E-43 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c12610 0d65043dcbac84da533a5aac4b66693a 257 Pfam PF02167 Cytochrome C1 family 37 84 2.1E-7 T 12-10-2018 IPR002326 Cytochrome c1 GO:0009055|GO:0020037 Reactome: R-HSA-1268020|Reactome: R-HSA-611105 VAPA_1c12610 0d65043dcbac84da533a5aac4b66693a 257 Pfam PF02167 Cytochrome C1 family 96 255 1.9E-12 T 12-10-2018 IPR002326 Cytochrome c1 GO:0009055|GO:0020037 Reactome: R-HSA-1268020|Reactome: R-HSA-611105 VAPA_1c12610 0d65043dcbac84da533a5aac4b66693a 257 SUPERFAMILY SSF46626 29 221 6.92E-50 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 VAPA_1c12610 0d65043dcbac84da533a5aac4b66693a 257 Gene3D G3DSA:1.10.760.10 25 222 2.4E-19 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 VAPA_1c12110 ec97b4c5eb1724abdcc10aa93673f876 1582 SUPERFAMILY SSF69336 1269 1548 2.75E-90 T 12-10-2018 IPR036485 Glutamate synthase, alpha subunit, C-terminal domain superfamily GO:0016491|GO:0055114 VAPA_1c12110 ec97b4c5eb1724abdcc10aa93673f876 1582 Gene3D G3DSA:3.20.20.70 807 1268 3.1E-204 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 VAPA_1c12110 ec97b4c5eb1724abdcc10aa93673f876 1582 Pfam PF01493 GXGXG motif 1302 1485 2.4E-74 T 12-10-2018 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0016491|GO:0055114 VAPA_1c12110 ec97b4c5eb1724abdcc10aa93673f876 1582 Pfam PF04898 Glutamate synthase central domain 476 762 1.3E-110 T 12-10-2018 IPR006982 Glutamate synthase, central-N GO:0006807|GO:0015930|GO:0055114 VAPA_1c12110 ec97b4c5eb1724abdcc10aa93673f876 1582 SUPERFAMILY SSF56235 25 450 2.99E-153 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal VAPA_1c12110 ec97b4c5eb1724abdcc10aa93673f876 1582 Gene3D G3DSA:2.160.20.60 1272 1559 1.6E-108 T 12-10-2018 IPR036485 Glutamate synthase, alpha subunit, C-terminal domain superfamily GO:0016491|GO:0055114 VAPA_1c12110 ec97b4c5eb1724abdcc10aa93673f876 1582 Pfam PF01645 Conserved region in glutamate synthase 823 1220 1.6E-152 T 12-10-2018 IPR002932 Glutamate synthase domain GO:0006537|GO:0015930|GO:0016638|GO:0055114 VAPA_1c12110 ec97b4c5eb1724abdcc10aa93673f876 1582 SUPERFAMILY SSF51395 467 1253 3.7E-263 T 12-10-2018 VAPA_1c12110 ec97b4c5eb1724abdcc10aa93673f876 1582 Pfam PF00310 Glutamine amidotransferases class-II 25 448 2.3E-187 T 12-10-2018 IPR017932 Glutamine amidotransferase type 2 domain VAPA_1c12110 ec97b4c5eb1724abdcc10aa93673f876 1582 Gene3D G3DSA:3.20.20.70 459 806 2.4E-121 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 VAPA_1c12110 ec97b4c5eb1724abdcc10aa93673f876 1582 Gene3D G3DSA:3.60.20.10 25 458 2.2E-183 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal VAPA_1c37520 5965a8f6d8e490ca1e66acd510993564 145 SUPERFAMILY SSF54427 5 131 1.5E-28 T 12-10-2018 IPR032710 NTF2-like domain superfamily VAPA_1c37520 5965a8f6d8e490ca1e66acd510993564 145 Pfam PF12680 SnoaL-like domain 11 117 3.2E-12 T 12-10-2018 IPR037401 SnoaL-like domain VAPA_1c37520 5965a8f6d8e490ca1e66acd510993564 145 Gene3D G3DSA:3.10.450.50 1 133 2.7E-33 T 12-10-2018 VAPA_1c38090 95891abbdda01341b1fb1d5db66e690e 283 Gene3D G3DSA:1.10.3720.10 8 270 5.1E-57 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c38090 95891abbdda01341b1fb1d5db66e690e 283 SUPERFAMILY SSF161098 15 282 3.92E-65 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c38090 95891abbdda01341b1fb1d5db66e690e 283 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 96 271 4.7E-15 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 VAPA_1c38700 e898c8d190c85355fb100cb03515f70c 1520 SUPERFAMILY SSF53901 14 440 7.29E-79 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 VAPA_1c38700 e898c8d190c85355fb100cb03515f70c 1520 Gene3D G3DSA:3.40.47.10 13 445 2.7E-161 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 VAPA_1c38700 e898c8d190c85355fb100cb03515f70c 1520 Pfam PF00550 Phosphopantetheine attachment site 1434 1497 1.0E-15 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain VAPA_1c38700 e898c8d190c85355fb100cb03515f70c 1520 Gene3D G3DSA:3.30.70.250 668 728 4.2E-136 T 12-10-2018 VAPA_1c38700 e898c8d190c85355fb100cb03515f70c 1520 Gene3D G3DSA:3.40.50.1820 1421 1519 3.6E-25 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c38700 e898c8d190c85355fb100cb03515f70c 1520 SUPERFAMILY SSF47336 1424 1497 5.76E-19 T 12-10-2018 IPR036736 ACP-like superfamily VAPA_1c38700 e898c8d190c85355fb100cb03515f70c 1520 SMART SM00823 Phosphopantetheine attachment site 1432 1501 5.5E-8 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 VAPA_1c38700 e898c8d190c85355fb100cb03515f70c 1520 SMART SM00825 Beta-ketoacyl synthase 15 445 7.8E-180 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain VAPA_1c38700 e898c8d190c85355fb100cb03515f70c 1520 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1456 1471 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site VAPA_1c38700 e898c8d190c85355fb100cb03515f70c 1520 Pfam PF08659 KR domain 1149 1346 2.1E-44 T 12-10-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 VAPA_1c38700 e898c8d190c85355fb100cb03515f70c 1520 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 14 266 8.9E-68 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal VAPA_1c38700 e898c8d190c85355fb100cb03515f70c 1520 Gene3D G3DSA:3.40.366.10 535 838 4.2E-136 T 12-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 VAPA_1c38700 e898c8d190c85355fb100cb03515f70c 1520 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1149 1347 1.2E-43 T 12-10-2018 VAPA_1c38700 e898c8d190c85355fb100cb03515f70c 1520 Pfam PF00698 Acyl transferase domain 537 822 1.2E-51 T 12-10-2018 IPR014043 Acyl transferase VAPA_1c38700 e898c8d190c85355fb100cb03515f70c 1520 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 274 392 3.4E-40 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal VAPA_1c38700 e898c8d190c85355fb100cb03515f70c 1520 SUPERFAMILY SSF52151 536 826 8.89E-65 T 12-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase VAPA_1c38700 e898c8d190c85355fb100cb03515f70c 1520 SUPERFAMILY SSF51735 902 1134 7.06E-23 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c38700 e898c8d190c85355fb100cb03515f70c 1520 Gene3D G3DSA:3.30.70.3290 458 867 4.2E-136 T 12-10-2018 VAPA_1c38700 e898c8d190c85355fb100cb03515f70c 1520 SUPERFAMILY SSF55048 667 727 2.62E-8 T 12-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding VAPA_1c38700 e898c8d190c85355fb100cb03515f70c 1520 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 539 842 2.0E-94 T 12-10-2018 IPR020801 Polyketide synthase, acyl transferase domain VAPA_1c38700 e898c8d190c85355fb100cb03515f70c 1520 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 179 195 - T 12-10-2018 IPR018201 Beta-ketoacyl synthase, active site VAPA_1c38700 e898c8d190c85355fb100cb03515f70c 1520 SUPERFAMILY SSF51735 1146 1353 7.38E-32 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c38700 e898c8d190c85355fb100cb03515f70c 1520 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 395 508 5.1E-20 T 12-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 VAPA_1c38700 e898c8d190c85355fb100cb03515f70c 1520 Gene3D G3DSA:3.40.50.720 880 1406 3.2E-91 T 12-10-2018 VAPA_2c13280 89b4a8eacda89b821c12ee821f6e08af 244 Pfam PF07996 Type IV secretion system proteins 24 225 1.3E-42 T 12-10-2018 IPR014158 Type IV secretion system, VirB5 VAPA_2c13280 89b4a8eacda89b821c12ee821f6e08af 244 Gene3D G3DSA:1.20.58.430 24 227 1.6E-44 T 12-10-2018 IPR023220 Type IV secretion system, VirB5-domain VAPA_2c13280 89b4a8eacda89b821c12ee821f6e08af 244 SUPERFAMILY SSF101082 24 227 1.02E-29 T 12-10-2018 VAPA_1c43980 0ca8f533d206029d0051d401c3638ec8 1215 SMART SM00388 762 828 1.2E-17 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 VAPA_1c43980 0ca8f533d206029d0051d401c3638ec8 1215 SUPERFAMILY SSF55874 819 981 2.88E-40 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_1c43980 0ca8f533d206029d0051d401c3638ec8 1215 Gene3D G3DSA:1.10.287.130 726 826 2.1E-22 T 12-10-2018 VAPA_1c43980 0ca8f533d206029d0051d401c3638ec8 1215 SMART SM00448 1011 1124 5.7E-12 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_1c43980 0ca8f533d206029d0051d401c3638ec8 1215 SUPERFAMILY SSF47384 750 829 3.34E-18 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 VAPA_1c43980 0ca8f533d206029d0051d401c3638ec8 1215 Pfam PF00072 Response regulator receiver domain 1014 1122 3.8E-12 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_1c43980 0ca8f533d206029d0051d401c3638ec8 1215 Gene3D G3DSA:3.30.565.10 827 986 3.7E-45 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_1c43980 0ca8f533d206029d0051d401c3638ec8 1215 SMART SM00387 875 987 5.5E-36 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase VAPA_1c43980 0ca8f533d206029d0051d401c3638ec8 1215 Gene3D G3DSA:3.40.50.12740 1010 1210 2.0E-21 T 12-10-2018 VAPA_1c43980 0ca8f533d206029d0051d401c3638ec8 1215 SUPERFAMILY SSF52172 1009 1133 1.57E-24 T 12-10-2018 IPR011006 CheY-like superfamily VAPA_1c43980 0ca8f533d206029d0051d401c3638ec8 1215 Gene3D G3DSA:1.10.4160.10 36 424 3.1E-14 T 12-10-2018 IPR038271 Purine-cytosine permease superfamily VAPA_1c43980 0ca8f533d206029d0051d401c3638ec8 1215 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 876 981 2.7E-26 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase VAPA_1c43980 0ca8f533d206029d0051d401c3638ec8 1215 Pfam PF00512 His Kinase A (phospho-acceptor) domain 762 828 3.9E-14 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 VAPA_1c43980 0ca8f533d206029d0051d401c3638ec8 1215 PRINTS PR00344 Bacterial sensor protein C-terminal signature 969 982 1.0E-12 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c43980 0ca8f533d206029d0051d401c3638ec8 1215 PRINTS PR00344 Bacterial sensor protein C-terminal signature 945 963 1.0E-12 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c43980 0ca8f533d206029d0051d401c3638ec8 1215 PRINTS PR00344 Bacterial sensor protein C-terminal signature 911 925 1.0E-12 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c43980 0ca8f533d206029d0051d401c3638ec8 1215 PRINTS PR00344 Bacterial sensor protein C-terminal signature 929 939 1.0E-12 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c14240 b16e6370043b254d7eeec873a4605d88 538 Pfam PF00005 ABC transporter 303 452 1.3E-32 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c14240 b16e6370043b254d7eeec873a4605d88 538 Pfam PF00005 ABC transporter 27 184 3.8E-26 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c14240 b16e6370043b254d7eeec873a4605d88 538 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 236 270 6.2E-5 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 VAPA_1c14240 b16e6370043b254d7eeec873a4605d88 538 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 504 529 5.6E-4 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 VAPA_1c14240 b16e6370043b254d7eeec873a4605d88 538 SUPERFAMILY SSF52540 282 524 5.02E-71 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c14240 b16e6370043b254d7eeec873a4605d88 538 Gene3D G3DSA:3.40.50.300 4 278 4.9E-78 T 12-10-2018 VAPA_1c14240 b16e6370043b254d7eeec873a4605d88 538 Gene3D G3DSA:3.40.50.300 279 537 1.9E-82 T 12-10-2018 VAPA_1c14240 b16e6370043b254d7eeec873a4605d88 538 SUPERFAMILY SSF52540 7 255 4.86E-59 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c14240 b16e6370043b254d7eeec873a4605d88 538 ProSitePatterns PS00211 ABC transporters family signature. 425 439 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_1c14240 b16e6370043b254d7eeec873a4605d88 538 SMART SM00382 311 502 9.8E-19 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c14240 b16e6370043b254d7eeec873a4605d88 538 SMART SM00382 35 234 1.3E-17 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c14240 b16e6370043b254d7eeec873a4605d88 538 ProSitePatterns PS00211 ABC transporters family signature. 157 171 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_1c22080 f4f936b9c26fe2e4a20ab798f4559da8 272 Pfam PF00005 ABC transporter 24 178 4.6E-25 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c22080 f4f936b9c26fe2e4a20ab798f4559da8 272 SMART SM00382 32 228 5.5E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c22080 f4f936b9c26fe2e4a20ab798f4559da8 272 Gene3D G3DSA:3.40.50.300 1 253 4.3E-49 T 12-10-2018 VAPA_1c22080 f4f936b9c26fe2e4a20ab798f4559da8 272 SUPERFAMILY SSF52540 4 238 5.33E-45 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c22080 f4f936b9c26fe2e4a20ab798f4559da8 272 ProSitePatterns PS00211 ABC transporters family signature. 151 165 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_1c29020 85503990d3d9a8674f15f44997f32de8 119 Pfam PF02617 ATP-dependent Clp protease adaptor protein ClpS 36 113 5.7E-33 T 12-10-2018 IPR003769 Adaptor protein ClpS, core GO:0030163 Reactome: R-HSA-983168 VAPA_1c29020 85503990d3d9a8674f15f44997f32de8 119 SUPERFAMILY SSF54736 33 117 4.5E-31 T 12-10-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like VAPA_1c29020 85503990d3d9a8674f15f44997f32de8 119 Gene3D G3DSA:3.30.1390.10 16 119 1.4E-40 T 12-10-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like VAPA_1c29020 85503990d3d9a8674f15f44997f32de8 119 Hamap MF_00302 ATP-dependent Clp protease adapter protein ClpS [clpS]. 7 113 27.676 T 12-10-2018 IPR022935 ATP-dependent Clp protease adaptor protein ClpS VAPA_2c07610 0e88a5d92bd72f4c9408aa65aaf0fe32 527 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 401 410 - T 12-10-2018 IPR025944 Sigma-54 interaction domain, conserved site VAPA_2c07610 0e88a5d92bd72f4c9408aa65aaf0fe32 527 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 212 225 - T 12-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 VAPA_2c07610 0e88a5d92bd72f4c9408aa65aaf0fe32 527 Gene3D G3DSA:3.40.50.300 180 358 2.2E-62 T 12-10-2018 VAPA_2c07610 0e88a5d92bd72f4c9408aa65aaf0fe32 527 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 274 289 - T 12-10-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 VAPA_2c07610 0e88a5d92bd72f4c9408aa65aaf0fe32 527 Pfam PF02954 Bacterial regulatory protein, Fis family 479 518 3.8E-5 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 VAPA_2c07610 0e88a5d92bd72f4c9408aa65aaf0fe32 527 Gene3D G3DSA:3.30.450.40 13 169 3.9E-9 T 12-10-2018 IPR029016 GAF-like domain superfamily VAPA_2c07610 0e88a5d92bd72f4c9408aa65aaf0fe32 527 SUPERFAMILY SSF46689 473 519 4.48E-7 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 VAPA_2c07610 0e88a5d92bd72f4c9408aa65aaf0fe32 527 SMART SM00382 208 351 8.8E-10 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_2c07610 0e88a5d92bd72f4c9408aa65aaf0fe32 527 Gene3D G3DSA:1.10.10.60 470 521 1.7E-11 T 12-10-2018 VAPA_2c07610 0e88a5d92bd72f4c9408aa65aaf0fe32 527 SUPERFAMILY SSF55781 22 167 7.11E-10 T 12-10-2018 VAPA_2c07610 0e88a5d92bd72f4c9408aa65aaf0fe32 527 Gene3D G3DSA:1.10.8.60 359 423 8.8E-17 T 12-10-2018 VAPA_2c07610 0e88a5d92bd72f4c9408aa65aaf0fe32 527 SUPERFAMILY SSF52540 188 422 1.56E-63 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_2c07610 0e88a5d92bd72f4c9408aa65aaf0fe32 527 Pfam PF00158 Sigma-54 interaction domain 188 354 2.2E-67 T 12-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 VAPA_1c30770 7b019eba4cd1affa7a56b9c7a39d06ee 473 SUPERFAMILY SSF47384 231 309 1.96E-11 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 VAPA_1c30770 7b019eba4cd1affa7a56b9c7a39d06ee 473 SUPERFAMILY SSF55874 300 471 1.7E-34 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_1c30770 7b019eba4cd1affa7a56b9c7a39d06ee 473 PRINTS PR00344 Bacterial sensor protein C-terminal signature 393 407 1.6E-12 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c30770 7b019eba4cd1affa7a56b9c7a39d06ee 473 PRINTS PR00344 Bacterial sensor protein C-terminal signature 411 421 1.6E-12 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c30770 7b019eba4cd1affa7a56b9c7a39d06ee 473 PRINTS PR00344 Bacterial sensor protein C-terminal signature 423 441 1.6E-12 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c30770 7b019eba4cd1affa7a56b9c7a39d06ee 473 PRINTS PR00344 Bacterial sensor protein C-terminal signature 454 467 1.6E-12 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c30770 7b019eba4cd1affa7a56b9c7a39d06ee 473 SMART SM00387 356 470 8.5E-26 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase VAPA_1c30770 7b019eba4cd1affa7a56b9c7a39d06ee 473 Gene3D G3DSA:3.30.565.10 309 468 2.5E-32 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_1c30770 7b019eba4cd1affa7a56b9c7a39d06ee 473 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 361 451 9.7E-18 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase VAPA_1c30770 7b019eba4cd1affa7a56b9c7a39d06ee 473 Pfam PF00512 His Kinase A (phospho-acceptor) domain 249 310 4.2E-9 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 VAPA_1c30770 7b019eba4cd1affa7a56b9c7a39d06ee 473 Pfam PF08521 Two-component sensor kinase N-terminal 20 171 1.7E-38 T 12-10-2018 IPR013727 Two-component sensor kinase, N-terminal VAPA_1c30770 7b019eba4cd1affa7a56b9c7a39d06ee 473 SMART SM00388 248 311 6.4E-11 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 VAPA_1c30770 7b019eba4cd1affa7a56b9c7a39d06ee 473 Gene3D G3DSA:1.10.287.130 199 308 1.5E-18 T 12-10-2018 VAPA_1c18010 bcce42fa5a14f95100ef925c48442c1a 645 PRINTS PR00301 70kDa heat shock protein signature 366 386 1.3E-79 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 VAPA_1c18010 bcce42fa5a14f95100ef925c48442c1a 645 PRINTS PR00301 70kDa heat shock protein signature 3 16 1.3E-79 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 VAPA_1c18010 bcce42fa5a14f95100ef925c48442c1a 645 PRINTS PR00301 70kDa heat shock protein signature 389 408 1.3E-79 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 VAPA_1c18010 bcce42fa5a14f95100ef925c48442c1a 645 PRINTS PR00301 70kDa heat shock protein signature 54 62 1.3E-79 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 VAPA_1c18010 bcce42fa5a14f95100ef925c48442c1a 645 PRINTS PR00301 70kDa heat shock protein signature 470 486 1.3E-79 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 VAPA_1c18010 bcce42fa5a14f95100ef925c48442c1a 645 PRINTS PR00301 70kDa heat shock protein signature 199 209 1.3E-79 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 VAPA_1c18010 bcce42fa5a14f95100ef925c48442c1a 645 PRINTS PR00301 70kDa heat shock protein signature 335 351 1.3E-79 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 VAPA_1c18010 bcce42fa5a14f95100ef925c48442c1a 645 PRINTS PR00301 70kDa heat shock protein signature 138 158 1.3E-79 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 VAPA_1c18010 bcce42fa5a14f95100ef925c48442c1a 645 PRINTS PR00301 70kDa heat shock protein signature 31 43 1.3E-79 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 VAPA_1c18010 bcce42fa5a14f95100ef925c48442c1a 645 Gene3D G3DSA:1.20.1270.10 525 608 1.1E-23 T 12-10-2018 IPR029048 Heat shock protein 70kD, C-terminal domain superfamily Reactome: R-HSA-3371453 VAPA_1c18010 bcce42fa5a14f95100ef925c48442c1a 645 SUPERFAMILY SSF53067 188 383 3.64E-67 T 12-10-2018 VAPA_1c18010 bcce42fa5a14f95100ef925c48442c1a 645 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 338 352 - T 12-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 VAPA_1c18010 bcce42fa5a14f95100ef925c48442c1a 645 SUPERFAMILY SSF100920 385 541 1.44E-59 T 12-10-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain superfamily Reactome: R-HSA-3371453 VAPA_1c18010 bcce42fa5a14f95100ef925c48442c1a 645 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 193 206 - T 12-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 VAPA_1c18010 bcce42fa5a14f95100ef925c48442c1a 645 Pfam PF00012 Hsp70 protein 4 604 3.7E-261 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 VAPA_1c18010 bcce42fa5a14f95100ef925c48442c1a 645 TIGRFAM TIGR02350 prok_dnaK: chaperone protein DnaK 3 604 1.8E-286 T 12-10-2018 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453|Reactome: R-HSA-8949613|Reactome: R-HSA-8950505 VAPA_1c18010 bcce42fa5a14f95100ef925c48442c1a 645 SUPERFAMILY SSF100934 508 606 1.1E-18 T 12-10-2018 IPR029048 Heat shock protein 70kD, C-terminal domain superfamily Reactome: R-HSA-3371453 VAPA_1c18010 bcce42fa5a14f95100ef925c48442c1a 645 SUPERFAMILY SSF53067 4 184 1.14E-64 T 12-10-2018 VAPA_1c18010 bcce42fa5a14f95100ef925c48442c1a 645 Hamap MF_00332 Chaperone protein DnaK [dnaK]. 1 642 36.444 T 12-10-2018 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453|Reactome: R-HSA-8949613|Reactome: R-HSA-8950505 VAPA_1c18010 bcce42fa5a14f95100ef925c48442c1a 645 Gene3D G3DSA:2.60.34.10 384 524 2.7E-65 T 12-10-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain superfamily Reactome: R-HSA-3371453 VAPA_1c18010 bcce42fa5a14f95100ef925c48442c1a 645 Gene3D G3DSA:3.90.640.10 230 317 4.2E-164 T 12-10-2018 VAPA_1c18010 bcce42fa5a14f95100ef925c48442c1a 645 Gene3D G3DSA:3.30.420.40 180 367 4.2E-164 T 12-10-2018 VAPA_1c18010 bcce42fa5a14f95100ef925c48442c1a 645 Gene3D G3DSA:3.30.420.40 5 380 4.2E-164 T 12-10-2018 VAPA_1c18010 bcce42fa5a14f95100ef925c48442c1a 645 ProSitePatterns PS00297 Heat shock hsp70 proteins family signature 1. 7 14 - T 12-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 VAPA_1c27040 d2df690171e78919613dcc9a0c76ed55 140 TIGRFAM TIGR00149 TIGR00149_YjbQ: secondary thiamine-phosphate synthase enzyme 14 139 8.4E-42 T 12-10-2018 IPR001602 Uncharacterised protein family UPF0047 VAPA_1c27040 d2df690171e78919613dcc9a0c76ed55 140 Pfam PF01894 Uncharacterised protein family UPF0047 20 136 1.9E-39 T 12-10-2018 IPR001602 Uncharacterised protein family UPF0047 VAPA_1c27040 d2df690171e78919613dcc9a0c76ed55 140 SUPERFAMILY SSF111038 3 139 2.75E-48 T 12-10-2018 IPR035917 YjbQ-like superfamily VAPA_1c27040 d2df690171e78919613dcc9a0c76ed55 140 Gene3D G3DSA:2.60.120.460 2 140 5.3E-43 T 12-10-2018 IPR035917 YjbQ-like superfamily VAPA_1c27040 d2df690171e78919613dcc9a0c76ed55 140 PIRSF PIRSF004681 1 140 4.2E-52 T 12-10-2018 IPR001602 Uncharacterised protein family UPF0047 VAPA_1c19370 fba2fe857d35ed40e0d8eee804faaa01 294 Gene3D G3DSA:3.40.190.10 164 264 4.6E-65 T 12-10-2018 VAPA_1c19370 fba2fe857d35ed40e0d8eee804faaa01 294 Gene3D G3DSA:1.10.10.10 4 90 4.5E-22 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c19370 fba2fe857d35ed40e0d8eee804faaa01 294 Pfam PF03466 LysR substrate binding domain 88 293 6.9E-43 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_1c19370 fba2fe857d35ed40e0d8eee804faaa01 294 SUPERFAMILY SSF46785 5 112 1.03E-20 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c19370 fba2fe857d35ed40e0d8eee804faaa01 294 Gene3D G3DSA:3.40.190.10 93 290 4.6E-65 T 12-10-2018 VAPA_1c19370 fba2fe857d35ed40e0d8eee804faaa01 294 SUPERFAMILY SSF53850 89 294 1.81E-42 T 12-10-2018 VAPA_1c19370 fba2fe857d35ed40e0d8eee804faaa01 294 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 63 7.3E-17 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c42830 ae2378d06f5bbe5781dc3315d79c446d 336 SUPERFAMILY SSF54427 209 334 1.25E-8 T 12-10-2018 IPR032710 NTF2-like domain superfamily VAPA_1c42830 ae2378d06f5bbe5781dc3315d79c446d 336 Pfam PF04280 Tim44-like domain 202 333 2.8E-19 T 12-10-2018 IPR007379 Tim44-like domain VAPA_1c42830 ae2378d06f5bbe5781dc3315d79c446d 336 SMART SM00978 199 334 3.5E-37 T 12-10-2018 IPR007379 Tim44-like domain VAPA_2c08690 7c9584f886a11b543d5ecc2f45b8cbc4 118 SUPERFAMILY SSF46626 28 117 1.89E-26 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 VAPA_2c08690 7c9584f886a11b543d5ecc2f45b8cbc4 118 PRINTS PR00604 Class IA and IB cytochrome C signature 31 38 1.2E-17 T 12-10-2018 IPR002327 Cytochrome c, class IA/ IB GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 VAPA_2c08690 7c9584f886a11b543d5ecc2f45b8cbc4 118 PRINTS PR00604 Class IA and IB cytochrome C signature 72 88 1.2E-17 T 12-10-2018 IPR002327 Cytochrome c, class IA/ IB GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 VAPA_2c08690 7c9584f886a11b543d5ecc2f45b8cbc4 118 PRINTS PR00604 Class IA and IB cytochrome C signature 42 57 1.2E-17 T 12-10-2018 IPR002327 Cytochrome c, class IA/ IB GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 VAPA_2c08690 7c9584f886a11b543d5ecc2f45b8cbc4 118 PRINTS PR00604 Class IA and IB cytochrome C signature 108 116 1.2E-17 T 12-10-2018 IPR002327 Cytochrome c, class IA/ IB GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 VAPA_2c08690 7c9584f886a11b543d5ecc2f45b8cbc4 118 PRINTS PR00604 Class IA and IB cytochrome C signature 58 68 1.2E-17 T 12-10-2018 IPR002327 Cytochrome c, class IA/ IB GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 VAPA_2c08690 7c9584f886a11b543d5ecc2f45b8cbc4 118 PRINTS PR00604 Class IA and IB cytochrome C signature 91 101 1.2E-17 T 12-10-2018 IPR002327 Cytochrome c, class IA/ IB GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 VAPA_2c08690 7c9584f886a11b543d5ecc2f45b8cbc4 118 Pfam PF00034 Cytochrome c 30 117 1.9E-7 T 12-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 VAPA_2c08690 7c9584f886a11b543d5ecc2f45b8cbc4 118 Gene3D G3DSA:1.10.760.10 7 116 3.6E-35 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 VAPA_1c47400 33d8760f3293b2cd5221d6fdf61f9485 265 Pfam PF12872 OST-HTH/LOTUS domain 192 255 2.8E-14 T 12-10-2018 IPR025605 OST-HTH/LOTUS domain VAPA_1c47400 33d8760f3293b2cd5221d6fdf61f9485 265 Gene3D G3DSA:3.40.50.1010 28 174 9.4E-15 T 12-10-2018 VAPA_1c47400 33d8760f3293b2cd5221d6fdf61f9485 265 Pfam PF01936 NYN domain 37 170 7.6E-32 T 12-10-2018 IPR021139 NYN domain, limkain-b1-type VAPA_1c47400 33d8760f3293b2cd5221d6fdf61f9485 265 Gene3D G3DSA:1.10.10.1880 194 265 7.3E-22 T 12-10-2018 VAPA_1c15570 8a2a563476933db8aa84d3d61693faba 346 Pfam PF00586 AIR synthase related protein, N-terminal domain 61 165 7.4E-14 T 12-10-2018 IPR016188 PurM-like, N-terminal domain VAPA_1c15570 8a2a563476933db8aa84d3d61693faba 346 Pfam PF02769 AIR synthase related protein, C-terminal domain 178 343 2.9E-32 T 12-10-2018 IPR010918 PurM-like, C-terminal domain VAPA_1c15570 8a2a563476933db8aa84d3d61693faba 346 Gene3D G3DSA:3.30.1330.10 9 172 1.2E-68 T 12-10-2018 IPR036921 PurM-like, N-terminal domain superfamily VAPA_1c15570 8a2a563476933db8aa84d3d61693faba 346 SUPERFAMILY SSF55326 9 172 1.92E-52 T 12-10-2018 IPR036921 PurM-like, N-terminal domain superfamily VAPA_1c15570 8a2a563476933db8aa84d3d61693faba 346 Gene3D G3DSA:3.90.650.10 173 345 1.1E-61 T 12-10-2018 IPR036676 PurM-like, C-terminal domain superfamily VAPA_1c15570 8a2a563476933db8aa84d3d61693faba 346 TIGRFAM TIGR00878 purM: phosphoribosylformylglycinamidine cyclo-ligase 9 336 5.3E-132 T 12-10-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 VAPA_1c15570 8a2a563476933db8aa84d3d61693faba 346 Hamap MF_00741 Phosphoribosylformylglycinamidine cyclo-ligase [purM]. 9 345 45.284 T 12-10-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 VAPA_1c15570 8a2a563476933db8aa84d3d61693faba 346 SUPERFAMILY SSF56042 173 343 9.72E-55 T 12-10-2018 IPR036676 PurM-like, C-terminal domain superfamily VAPA_1c25460 fc1daf45002ae2b0ef19d09b0b66d399 445 Pfam PF00009 Elongation factor Tu GTP binding domain 21 226 1.2E-35 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 VAPA_1c25460 fc1daf45002ae2b0ef19d09b0b66d399 445 SUPERFAMILY SSF50447 243 333 2.0E-17 T 12-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily VAPA_1c25460 fc1daf45002ae2b0ef19d09b0b66d399 445 Gene3D G3DSA:3.40.50.300 8 239 1.3E-53 T 12-10-2018 VAPA_1c25460 fc1daf45002ae2b0ef19d09b0b66d399 445 PRINTS PR00315 GTP-binding elongation factor signature 111 122 5.9E-9 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 VAPA_1c25460 fc1daf45002ae2b0ef19d09b0b66d399 445 PRINTS PR00315 GTP-binding elongation factor signature 75 83 5.9E-9 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 VAPA_1c25460 fc1daf45002ae2b0ef19d09b0b66d399 445 PRINTS PR00315 GTP-binding elongation factor signature 22 35 5.9E-9 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 VAPA_1c25460 fc1daf45002ae2b0ef19d09b0b66d399 445 PRINTS PR00315 GTP-binding elongation factor signature 95 105 5.9E-9 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 VAPA_1c25460 fc1daf45002ae2b0ef19d09b0b66d399 445 TIGRFAM TIGR02034 CysN: sulfate adenylyltransferase, large subunit 21 437 1.7E-125 T 12-10-2018 IPR011779 Sulphate adenylyltransferase, large subunit GO:0006790 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 VAPA_1c25460 fc1daf45002ae2b0ef19d09b0b66d399 445 Gene3D G3DSA:2.40.30.10 241 333 2.8E-18 T 12-10-2018 VAPA_1c25460 fc1daf45002ae2b0ef19d09b0b66d399 445 SUPERFAMILY SSF50465 338 438 4.22E-24 T 12-10-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal VAPA_1c25460 fc1daf45002ae2b0ef19d09b0b66d399 445 Gene3D G3DSA:2.40.30.10 336 439 9.3E-26 T 12-10-2018 VAPA_1c25460 fc1daf45002ae2b0ef19d09b0b66d399 445 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 68 83 - T 12-10-2018 IPR031157 Tr-type G domain, conserved site VAPA_1c25460 fc1daf45002ae2b0ef19d09b0b66d399 445 SUPERFAMILY SSF52540 19 253 3.12E-45 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c42690 31db49309e5bf3a1a82c3fe13b560ed9 186 Gene3D G3DSA:1.20.1260.10 43 186 8.0E-53 T 12-10-2018 IPR012347 Ferritin-like VAPA_1c42690 31db49309e5bf3a1a82c3fe13b560ed9 186 Pfam PF00210 Ferritin-like domain 49 185 1.8E-30 T 12-10-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 VAPA_1c42690 31db49309e5bf3a1a82c3fe13b560ed9 186 PIRSF PIRSF018063 25 186 5.7E-54 T 12-10-2018 IPR014490 DNA-binding protein from starved cells-like VAPA_1c42690 31db49309e5bf3a1a82c3fe13b560ed9 186 SUPERFAMILY SSF47240 43 185 9.69E-39 T 12-10-2018 IPR009078 Ferritin-like superfamily VAPA_2c01710 fb6a4dd872d391eef620ce71e32fb3f8 274 SUPERFAMILY SSF51556 10 272 6.4E-69 T 12-10-2018 IPR032466 Metal-dependent hydrolase VAPA_2c01710 fb6a4dd872d391eef620ce71e32fb3f8 274 Pfam PF04909 Amidohydrolase 12 272 5.9E-34 T 12-10-2018 IPR006680 Amidohydrolase-related GO:0016787 VAPA_2c01710 fb6a4dd872d391eef620ce71e32fb3f8 274 Gene3D G3DSA:3.20.20.140 3 273 8.4E-75 T 12-10-2018 VAPA_1c16470 c6a8165c32d633c5ad2b9d50cae49d4f 332 SUPERFAMILY SSF52540 9 261 1.16E-71 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c16470 c6a8165c32d633c5ad2b9d50cae49d4f 332 Pfam PF00005 ABC transporter 37 190 6.0E-31 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c16470 c6a8165c32d633c5ad2b9d50cae49d4f 332 SMART SM00382 45 240 1.0E-15 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c16470 c6a8165c32d633c5ad2b9d50cae49d4f 332 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 242 307 2.2E-17 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 VAPA_1c16470 c6a8165c32d633c5ad2b9d50cae49d4f 332 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 240 331 1.6E-26 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 VAPA_1c16470 c6a8165c32d633c5ad2b9d50cae49d4f 332 Gene3D G3DSA:3.40.50.300 7 332 1.3E-96 T 12-10-2018 VAPA_1c16470 c6a8165c32d633c5ad2b9d50cae49d4f 332 ProSitePatterns PS00211 ABC transporters family signature. 163 177 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_2c06320 437f29c1905214721c757b52928dc1f4 448 Gene3D G3DSA:3.40.50.12240 20 441 2.1E-148 T 12-10-2018 VAPA_2c06320 437f29c1905214721c757b52928dc1f4 448 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 352 361 - T 12-10-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 VAPA_2c06320 437f29c1905214721c757b52928dc1f4 448 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 31 95 4.6E-8 T 12-10-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 VAPA_2c06320 437f29c1905214721c757b52928dc1f4 448 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 152 361 1.1E-72 T 12-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 VAPA_2c06320 437f29c1905214721c757b52928dc1f4 448 SUPERFAMILY SSF52540 100 367 2.15E-96 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_2c06320 437f29c1905214721c757b52928dc1f4 448 TIGRFAM TIGR01026 fliI_yscN: ATPase, FliI/YscN family 20 439 1.4E-168 T 12-10-2018 IPR005714 ATPase, type III secretion system, FliI/YscN GO:0005737|GO:0009058|GO:0016887|GO:0030254|GO:0030257 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 VAPA_2c06320 437f29c1905214721c757b52928dc1f4 448 SMART SM00382 164 345 1.7E-10 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_2c07150 bbfc19e17a9f9941c4909c9ed7d87ee2 305 Pfam PF03466 LysR substrate binding domain 87 291 2.3E-35 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_2c07150 bbfc19e17a9f9941c4909c9ed7d87ee2 305 SUPERFAMILY SSF46785 1 110 7.14E-25 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_2c07150 bbfc19e17a9f9941c4909c9ed7d87ee2 305 SUPERFAMILY SSF53850 88 295 2.78E-34 T 12-10-2018 VAPA_2c07150 bbfc19e17a9f9941c4909c9ed7d87ee2 305 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 4.2E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_2c07150 bbfc19e17a9f9941c4909c9ed7d87ee2 305 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 4.2E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_2c07150 bbfc19e17a9f9941c4909c9ed7d87ee2 305 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 4.2E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_2c07150 bbfc19e17a9f9941c4909c9ed7d87ee2 305 Gene3D G3DSA:3.40.190.10 90 272 5.5E-25 T 12-10-2018 VAPA_2c07150 bbfc19e17a9f9941c4909c9ed7d87ee2 305 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 61 7.8E-19 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_2c07150 bbfc19e17a9f9941c4909c9ed7d87ee2 305 Gene3D G3DSA:1.10.10.10 1 88 8.4E-25 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_2c07150 bbfc19e17a9f9941c4909c9ed7d87ee2 305 Gene3D G3DSA:3.40.190.10 163 266 5.5E-25 T 12-10-2018 VAPA_2c06610 3f075f55be5acc075a775f42ddf8948d 109 Pfam PF05336 L-rhamnose mutarotase 2 109 1.0E-27 T 12-10-2018 IPR008000 Rhamnose/fucose mutarotase GO:0005737|GO:0016857 VAPA_2c06610 3f075f55be5acc075a775f42ddf8948d 109 SUPERFAMILY SSF54909 1 109 3.81E-27 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel VAPA_2c06610 3f075f55be5acc075a775f42ddf8948d 109 Gene3D G3DSA:3.30.70.100 1 106 1.0E-12 T 12-10-2018 VAPA_1c39860 c2240dbe8eaba5e6d339c3c679426dd1 337 Gene3D G3DSA:3.40.190.10 145 326 9.2E-19 T 12-10-2018 VAPA_1c39860 c2240dbe8eaba5e6d339c3c679426dd1 337 Pfam PF09084 NMT1/THI5 like 54 266 3.0E-23 T 12-10-2018 IPR015168 SsuA/THI5-like VAPA_1c39860 c2240dbe8eaba5e6d339c3c679426dd1 337 SUPERFAMILY SSF53850 55 323 1.15E-33 T 12-10-2018 VAPA_1c39860 c2240dbe8eaba5e6d339c3c679426dd1 337 Gene3D G3DSA:3.40.190.10 31 132 6.8E-14 T 12-10-2018 VAPA_2c03520 2bde5485e0ebdccf5168b9546ca9513f 795 PIRSF PIRSF001174 8 784 7.0E-270 T 12-10-2018 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 VAPA_2c03520 2bde5485e0ebdccf5168b9546ca9513f 795 Gene3D G3DSA:1.10.8.60 500 592 2.6E-29 T 12-10-2018 VAPA_2c03520 2bde5485e0ebdccf5168b9546ca9513f 795 TIGRFAM TIGR00763 lon: endopeptidase La 21 779 3.5E-266 T 12-10-2018 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 VAPA_2c03520 2bde5485e0ebdccf5168b9546ca9513f 795 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 360 497 5.1E-21 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 VAPA_2c03520 2bde5485e0ebdccf5168b9546ca9513f 795 Gene3D G3DSA:3.30.230.10 604 790 2.5E-74 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup VAPA_2c03520 2bde5485e0ebdccf5168b9546ca9513f 795 Gene3D G3DSA:2.30.130.40 11 126 6.4E-29 T 12-10-2018 VAPA_2c03520 2bde5485e0ebdccf5168b9546ca9513f 795 SUPERFAMILY SSF54211 605 779 6.83E-52 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold VAPA_2c03520 2bde5485e0ebdccf5168b9546ca9513f 795 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 578 781 1.4E-79 T 12-10-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 VAPA_2c03520 2bde5485e0ebdccf5168b9546ca9513f 795 SMART SM00382 356 501 5.1E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_2c03520 2bde5485e0ebdccf5168b9546ca9513f 795 SUPERFAMILY SSF52540 323 589 2.79E-48 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_2c03520 2bde5485e0ebdccf5168b9546ca9513f 795 Gene3D G3DSA:3.40.50.300 322 499 7.9E-63 T 12-10-2018 VAPA_2c03520 2bde5485e0ebdccf5168b9546ca9513f 795 SMART SM00464 18 210 5.5E-43 T 12-10-2018 IPR003111 Lon, substrate-binding domain VAPA_2c03520 2bde5485e0ebdccf5168b9546ca9513f 795 ProSitePatterns PS01046 ATP-dependent serine proteases, lon family, serine active site. 686 694 - T 12-10-2018 IPR008268 Peptidase S16, active site GO:0004176|GO:0004252|GO:0006508 VAPA_2c03520 2bde5485e0ebdccf5168b9546ca9513f 795 SUPERFAMILY SSF88697 18 209 1.49E-38 T 12-10-2018 IPR015947 PUA-like superfamily VAPA_2c03520 2bde5485e0ebdccf5168b9546ca9513f 795 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 364 383 1.6E-49 T 12-10-2018 VAPA_2c03520 2bde5485e0ebdccf5168b9546ca9513f 795 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 713 732 1.6E-49 T 12-10-2018 VAPA_2c03520 2bde5485e0ebdccf5168b9546ca9513f 795 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 683 702 1.6E-49 T 12-10-2018 VAPA_2c03520 2bde5485e0ebdccf5168b9546ca9513f 795 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 736 754 1.6E-49 T 12-10-2018 VAPA_2c03520 2bde5485e0ebdccf5168b9546ca9513f 795 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 605 621 1.6E-49 T 12-10-2018 VAPA_2c03520 2bde5485e0ebdccf5168b9546ca9513f 795 Pfam PF02190 ATP-dependent protease La (LON) substrate-binding domain 19 209 8.0E-34 T 12-10-2018 IPR003111 Lon, substrate-binding domain VAPA_2c03520 2bde5485e0ebdccf5168b9546ca9513f 795 Hamap MF_01973 Lon protease [lon]. 19 782 62.568 T 12-10-2018 IPR027543 Lon protease, bacterial GO:0004176|GO:0004252|GO:0005524|GO:0006508|GO:0043565 VAPA_2c03520 2bde5485e0ebdccf5168b9546ca9513f 795 Gene3D G3DSA:1.20.58.1480 130 252 9.2E-30 T 12-10-2018 VAPA_1c54100 09a9d8a0e8f7be6d3d743574a530dcc7 981 Pfam PF01131 DNA topoisomerase 160 619 4.8E-107 T 12-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 VAPA_1c54100 09a9d8a0e8f7be6d3d743574a530dcc7 981 SMART SM00151 900 981 2.9E-26 T 12-10-2018 IPR019835 SWIB domain Reactome: R-HSA-3214858|Reactome: R-HSA-8939243 VAPA_1c54100 09a9d8a0e8f7be6d3d743574a530dcc7 981 Pfam PF02201 SWIB/MDM2 domain 909 978 2.0E-24 T 12-10-2018 IPR003121 SWIB/MDM2 domain GO:0005515 VAPA_1c54100 09a9d8a0e8f7be6d3d743574a530dcc7 981 Gene3D G3DSA:1.10.290.10 302 434 3.5E-154 T 12-10-2018 IPR013826 DNA topoisomerase, type IA, central region, subdomain 3 VAPA_1c54100 09a9d8a0e8f7be6d3d743574a530dcc7 981 TIGRFAM TIGR01056 topB: DNA topoisomerase III 3 644 1.6E-162 T 12-10-2018 IPR005738 DNA topoisomerase III GO:0003677|GO:0003916|GO:0006265 VAPA_1c54100 09a9d8a0e8f7be6d3d743574a530dcc7 981 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 104 117 1.4E-24 T 12-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 VAPA_1c54100 09a9d8a0e8f7be6d3d743574a530dcc7 981 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 336 345 1.4E-24 T 12-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 VAPA_1c54100 09a9d8a0e8f7be6d3d743574a530dcc7 981 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 199 217 1.4E-24 T 12-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 VAPA_1c54100 09a9d8a0e8f7be6d3d743574a530dcc7 981 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 420 436 1.4E-24 T 12-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 VAPA_1c54100 09a9d8a0e8f7be6d3d743574a530dcc7 981 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 544 558 1.4E-24 T 12-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 VAPA_1c54100 09a9d8a0e8f7be6d3d743574a530dcc7 981 Gene3D G3DSA:1.10.245.10 905 981 1.6E-22 T 12-10-2018 IPR036885 SWIB/MDM2 domain superfamily VAPA_1c54100 09a9d8a0e8f7be6d3d743574a530dcc7 981 Gene3D G3DSA:1.10.460.10 168 629 3.5E-154 T 12-10-2018 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 VAPA_1c54100 09a9d8a0e8f7be6d3d743574a530dcc7 981 Pfam PF01751 Toprim domain 4 140 4.4E-11 T 12-10-2018 IPR006171 TOPRIM domain VAPA_1c54100 09a9d8a0e8f7be6d3d743574a530dcc7 981 Pfam PF13342 C-terminal repeat of topoisomerase 677 740 3.2E-17 T 12-10-2018 IPR025589 Topoisomerase C-terminal repeat VAPA_1c54100 09a9d8a0e8f7be6d3d743574a530dcc7 981 Pfam PF13342 C-terminal repeat of topoisomerase 791 851 5.7E-15 T 12-10-2018 IPR025589 Topoisomerase C-terminal repeat VAPA_1c54100 09a9d8a0e8f7be6d3d743574a530dcc7 981 SUPERFAMILY SSF56712 3 635 1.12E-164 T 12-10-2018 IPR023405 DNA topoisomerase, type IA, core domain VAPA_1c54100 09a9d8a0e8f7be6d3d743574a530dcc7 981 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 330 345 - T 12-10-2018 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 VAPA_1c54100 09a9d8a0e8f7be6d3d743574a530dcc7 981 SUPERFAMILY SSF47592 908 980 5.23E-23 T 12-10-2018 IPR036885 SWIB/MDM2 domain superfamily VAPA_1c54100 09a9d8a0e8f7be6d3d743574a530dcc7 981 SMART SM00493 3 130 1.6E-12 T 12-10-2018 IPR006171 TOPRIM domain VAPA_1c54100 09a9d8a0e8f7be6d3d743574a530dcc7 981 Gene3D G3DSA:3.40.50.140 3 161 3.3E-46 T 12-10-2018 VAPA_1c54100 09a9d8a0e8f7be6d3d743574a530dcc7 981 SMART SM00436 134 229 1.0E-20 T 12-10-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 VAPA_1c54100 09a9d8a0e8f7be6d3d743574a530dcc7 981 Gene3D G3DSA:2.70.20.10 223 512 3.5E-154 T 12-10-2018 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 VAPA_1c54100 09a9d8a0e8f7be6d3d743574a530dcc7 981 SMART SM00437 293 581 2.8E-64 T 12-10-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 VAPA_1c45220 127f8abb0cbf16f4d81685320a5d6cf7 329 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 232 297 2.5E-17 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 VAPA_1c45220 127f8abb0cbf16f4d81685320a5d6cf7 329 SMART SM00382 32 230 1.9E-15 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c45220 127f8abb0cbf16f4d81685320a5d6cf7 329 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 231 316 3.6E-23 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 VAPA_1c45220 127f8abb0cbf16f4d81685320a5d6cf7 329 Pfam PF00005 ABC transporter 25 180 2.9E-28 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c45220 127f8abb0cbf16f4d81685320a5d6cf7 329 ProSitePatterns PS00211 ABC transporters family signature. 153 167 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_1c45220 127f8abb0cbf16f4d81685320a5d6cf7 329 SUPERFAMILY SSF52540 3 251 1.9E-65 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c45220 127f8abb0cbf16f4d81685320a5d6cf7 329 Gene3D G3DSA:3.40.50.300 2 326 1.5E-96 T 12-10-2018 VAPA_1c55060 845843ef763b8f1c4f7e7e14f60eb4b7 661 Gene3D G3DSA:1.20.1530.20 4 390 2.0E-85 T 12-10-2018 IPR038770 Sodium/solute symporter superfamily VAPA_1c55060 845843ef763b8f1c4f7e7e14f60eb4b7 661 TIGRFAM TIGR00932 2a37: transporter, monovalent cation:proton antiporter-2 (CPA2) family 11 290 4.1E-73 T 12-10-2018 IPR004771 K+/H+ exchanger GO:0006812|GO:0008324|GO:0016021 VAPA_1c55060 845843ef763b8f1c4f7e7e14f60eb4b7 661 SUPERFAMILY SSF51735 413 553 5.2E-32 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c55060 845843ef763b8f1c4f7e7e14f60eb4b7 661 SUPERFAMILY SSF116726 589 658 8.63E-9 T 12-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 VAPA_1c55060 845843ef763b8f1c4f7e7e14f60eb4b7 661 Pfam PF00999 Sodium/hydrogen exchanger family 7 377 2.9E-66 T 12-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 VAPA_1c55060 845843ef763b8f1c4f7e7e14f60eb4b7 661 Gene3D G3DSA:3.30.70.1450 586 660 6.8E-8 T 12-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 VAPA_1c55060 845843ef763b8f1c4f7e7e14f60eb4b7 661 Pfam PF02254 TrkA-N domain 416 529 4.6E-23 T 12-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 VAPA_1c55060 845843ef763b8f1c4f7e7e14f60eb4b7 661 Pfam PF02080 TrkA-C domain 592 657 2.8E-10 T 12-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 VAPA_1c55060 845843ef763b8f1c4f7e7e14f60eb4b7 661 Gene3D G3DSA:3.40.50.720 412 572 1.8E-35 T 12-10-2018 VAPA_2c00170 2babaec24578f96a54154df3e763637f 708 SMART SM00881 12 107 7.5E-31 T 12-10-2018 IPR003781 CoA-binding GO:0048037 VAPA_2c00170 2babaec24578f96a54154df3e763637f 708 Gene3D G3DSA:3.40.50.261 304 465 5.7E-29 T 12-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 VAPA_2c00170 2babaec24578f96a54154df3e763637f 708 Pfam PF13380 CoA binding domain 17 141 1.8E-21 T 12-10-2018 IPR003781 CoA-binding GO:0048037 VAPA_2c00170 2babaec24578f96a54154df3e763637f 708 Gene3D G3DSA:3.30.470.20 488 698 1.9E-58 T 12-10-2018 VAPA_2c00170 2babaec24578f96a54154df3e763637f 708 SUPERFAMILY SSF52210 309 461 1.03E-26 T 12-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 VAPA_2c00170 2babaec24578f96a54154df3e763637f 708 Gene3D G3DSA:3.40.50.720 7 136 2.6E-41 T 12-10-2018 VAPA_2c00170 2babaec24578f96a54154df3e763637f 708 Gene3D G3DSA:3.40.50.261 144 300 8.5E-40 T 12-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 VAPA_2c00170 2babaec24578f96a54154df3e763637f 708 Gene3D G3DSA:3.30.1490.20 506 581 1.9E-58 T 12-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 VAPA_2c00170 2babaec24578f96a54154df3e763637f 708 SUPERFAMILY SSF56059 488 699 5.74E-32 T 12-10-2018 VAPA_2c00170 2babaec24578f96a54154df3e763637f 708 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 163 299 4.8E-40 T 12-10-2018 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain VAPA_2c00170 2babaec24578f96a54154df3e763637f 708 SUPERFAMILY SSF52210 149 300 1.44E-34 T 12-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 VAPA_2c00170 2babaec24578f96a54154df3e763637f 708 SUPERFAMILY SSF51735 9 144 1.65E-33 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_2c00170 2babaec24578f96a54154df3e763637f 708 Pfam PF13549 ATP-grasp domain 486 698 4.2E-48 T 12-10-2018 VAPA_2c13130 0eb0a528ad24386dfba4599cca0c46c4 783 SMART SM00487 414 592 1.2E-24 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain VAPA_2c13130 0eb0a528ad24386dfba4599cca0c46c4 783 SUPERFAMILY SSF52540 326 577 3.69E-39 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_2c13130 0eb0a528ad24386dfba4599cca0c46c4 783 Gene3D G3DSA:3.40.50.300 412 582 1.9E-33 T 12-10-2018 VAPA_2c13130 0eb0a528ad24386dfba4599cca0c46c4 783 Pfam PF04851 Type III restriction enzyme, res subunit 417 559 9.3E-17 T 12-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 VAPA_2c13130 0eb0a528ad24386dfba4599cca0c46c4 783 Pfam PF00271 Helicase conserved C-terminal domain 632 733 1.4E-4 T 12-10-2018 IPR001650 Helicase, C-terminal VAPA_2c13130 0eb0a528ad24386dfba4599cca0c46c4 783 SUPERFAMILY SSF52540 523 772 2.48E-24 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_2c13130 0eb0a528ad24386dfba4599cca0c46c4 783 Gene3D G3DSA:3.40.50.300 594 777 1.1E-29 T 12-10-2018 VAPA_1c33250 f37789555f3143123f4d08e9c57c54b4 473 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 8 77 1.3E-12 T 12-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 VAPA_1c33250 f37789555f3143123f4d08e9c57c54b4 473 Pfam PF01926 50S ribosome-binding GTPase 10 154 4.1E-17 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 VAPA_1c33250 f37789555f3143123f4d08e9c57c54b4 473 SUPERFAMILY SSF52540 7 168 4.83E-21 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c33250 f37789555f3143123f4d08e9c57c54b4 473 Gene3D G3DSA:3.40.50.300 2 198 5.5E-28 T 12-10-2018 VAPA_1c33250 f37789555f3143123f4d08e9c57c54b4 473 Pfam PF11981 Domain of unknown function (DUF3482) 168 443 2.9E-67 T 12-10-2018 IPR021871 Protein of unknown function DUF3482 VAPA_2c06000 e01fc5cf425f8d592e76a47ea5bfa41a 619 Gene3D G3DSA:3.40.50.920 497 604 6.7E-16 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 VAPA_2c06000 e01fc5cf425f8d592e76a47ea5bfa41a 619 Gene3D G3DSA:3.40.50.970 204 400 1.2E-59 T 12-10-2018 VAPA_2c06000 e01fc5cf425f8d592e76a47ea5bfa41a 619 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 225 392 8.5E-49 T 12-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 VAPA_2c06000 e01fc5cf425f8d592e76a47ea5bfa41a 619 SUPERFAMILY SSF53323 18 196 4.71E-22 T 12-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 VAPA_2c06000 e01fc5cf425f8d592e76a47ea5bfa41a 619 SUPERFAMILY SSF52922 500 606 1.1E-12 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 VAPA_2c06000 e01fc5cf425f8d592e76a47ea5bfa41a 619 Gene3D G3DSA:3.40.920.10 14 203 5.5E-19 T 12-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 VAPA_2c06000 e01fc5cf425f8d592e76a47ea5bfa41a 619 TIGRFAM TIGR03710 OAFO_sf: 2-oxoacid:acceptor oxidoreductase, alpha subunit 15 600 9.0E-176 T 12-10-2018 IPR022367 2-oxoacid:acceptor oxidoreductase, alpha subunit KEGG: 00020+1.2.7.3|KEGG: 00720+1.2.7.3|MetaCyc: PWY-5392|MetaCyc: PWY-6969 VAPA_2c06000 e01fc5cf425f8d592e76a47ea5bfa41a 619 SUPERFAMILY SSF52518 212 484 1.91E-58 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold VAPA_2c06000 e01fc5cf425f8d592e76a47ea5bfa41a 619 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 25 190 2.5E-29 T 12-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 VAPA_1c26640 489c3554a4953e1b58760dfa7fde6401 533 Gene3D G3DSA:1.20.1720.10 33 242 5.7E-53 T 12-10-2018 VAPA_1c26640 489c3554a4953e1b58760dfa7fde6401 533 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 35 515 7.9E-78 T 12-10-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0016021|GO:0022857|GO:0055085 VAPA_1c26640 489c3554a4953e1b58760dfa7fde6401 533 Pfam PF07690 Major Facilitator Superfamily 39 430 2.6E-58 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 VAPA_1c26640 489c3554a4953e1b58760dfa7fde6401 533 SUPERFAMILY SSF103473 29 521 7.06E-71 T 12-10-2018 IPR036259 MFS transporter superfamily VAPA_1c47810 8f1264929aac2dfdb07a980d918fbf6a 539 SUPERFAMILY SSF52540 21 232 6.5E-49 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c47810 8f1264929aac2dfdb07a980d918fbf6a 539 Gene3D G3DSA:3.40.50.300 7 242 2.1E-48 T 12-10-2018 VAPA_1c47810 8f1264929aac2dfdb07a980d918fbf6a 539 Pfam PF00005 ABC transporter 24 174 9.2E-28 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c47810 8f1264929aac2dfdb07a980d918fbf6a 539 SMART SM00382 33 222 6.4E-14 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c47810 8f1264929aac2dfdb07a980d918fbf6a 539 SMART SM00382 282 495 6.3E-5 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c47810 8f1264929aac2dfdb07a980d918fbf6a 539 Gene3D G3DSA:3.40.50.300 263 534 1.9E-43 T 12-10-2018 VAPA_1c47810 8f1264929aac2dfdb07a980d918fbf6a 539 ProSitePatterns PS00211 ABC transporters family signature. 410 424 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_1c47810 8f1264929aac2dfdb07a980d918fbf6a 539 SUPERFAMILY SSF52540 268 490 8.51E-45 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c47810 8f1264929aac2dfdb07a980d918fbf6a 539 Pfam PF00005 ABC transporter 274 437 8.3E-19 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c18620 8cdbb54a06dff58fac046ee9ff426556 389 Pfam PF07690 Major Facilitator Superfamily 216 378 5.1E-17 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 VAPA_1c18620 8cdbb54a06dff58fac046ee9ff426556 389 Pfam PF07690 Major Facilitator Superfamily 12 198 1.7E-22 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 VAPA_1c18620 8cdbb54a06dff58fac046ee9ff426556 389 PRINTS PR01035 Tetracycline resistance protein signature 275 296 2.5E-7 T 12-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 VAPA_1c18620 8cdbb54a06dff58fac046ee9ff426556 389 PRINTS PR01035 Tetracycline resistance protein signature 131 153 2.5E-7 T 12-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 VAPA_1c18620 8cdbb54a06dff58fac046ee9ff426556 389 PRINTS PR01035 Tetracycline resistance protein signature 41 60 2.5E-7 T 12-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 VAPA_1c18620 8cdbb54a06dff58fac046ee9ff426556 389 PRINTS PR01035 Tetracycline resistance protein signature 336 359 2.5E-7 T 12-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 VAPA_1c18620 8cdbb54a06dff58fac046ee9ff426556 389 SUPERFAMILY SSF103473 12 386 5.23E-52 T 12-10-2018 IPR036259 MFS transporter superfamily VAPA_1c18620 8cdbb54a06dff58fac046ee9ff426556 389 Gene3D G3DSA:1.20.1250.20 9 382 1.2E-43 T 12-10-2018 VAPA_1c42240 1804a743f611c40b16c50410a609734e 957 Gene3D G3DSA:3.40.50.740 318 782 2.7E-177 T 12-10-2018 VAPA_1c42240 1804a743f611c40b16c50410a609734e 957 Gene3D G3DSA:2.40.40.20 815 936 8.6E-40 T 12-10-2018 VAPA_1c42240 1804a743f611c40b16c50410a609734e 957 Pfam PF00037 4Fe-4S binding domain 206 223 1.2E-5 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain VAPA_1c42240 1804a743f611c40b16c50410a609734e 957 Gene3D G3DSA:2.20.25.90 236 288 7.2E-21 T 12-10-2018 VAPA_1c42240 1804a743f611c40b16c50410a609734e 957 SUPERFAMILY SSF54862 89 229 8.97E-27 T 12-10-2018 VAPA_1c42240 1804a743f611c40b16c50410a609734e 957 TIGRFAM TIGR01591 Fdh-alpha: formate dehydrogenase, alpha subunit 241 934 3.2E-217 T 12-10-2018 IPR006478 Formate dehydrogenase, alpha subunit GO:0008863|GO:0015942|GO:0055114 KEGG: 00630+1.17.1.9|KEGG: 00680+1.17.1.9|MetaCyc: PWY-1881|MetaCyc: PWY-5497|MetaCyc: PWY-6696|MetaCyc: PWY-7985 VAPA_1c42240 1804a743f611c40b16c50410a609734e 957 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 14 88 7.7E-19 T 12-10-2018 VAPA_1c42240 1804a743f611c40b16c50410a609734e 957 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 208 219 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site VAPA_1c42240 1804a743f611c40b16c50410a609734e 957 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 236 287 2.9E-15 T 12-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VAPA_1c42240 1804a743f611c40b16c50410a609734e 957 SUPERFAMILY SSF50692 788 936 1.38E-41 T 12-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily VAPA_1c42240 1804a743f611c40b16c50410a609734e 957 ProSitePatterns PS00490 Prokaryotic molybdopterin oxidoreductases signature 2. 680 697 - T 12-10-2018 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 VAPA_1c42240 1804a743f611c40b16c50410a609734e 957 PIRSF PIRSF036643 10 945 0.0 T 12-10-2018 VAPA_1c42240 1804a743f611c40b16c50410a609734e 957 SMART SM00926 235 288 6.1E-18 T 12-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VAPA_1c42240 1804a743f611c40b16c50410a609734e 957 SUPERFAMILY SSF54292 15 117 6.93E-30 T 12-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 VAPA_1c42240 1804a743f611c40b16c50410a609734e 957 Gene3D G3DSA:3.30.70.20 144 226 3.3E-21 T 12-10-2018 VAPA_1c42240 1804a743f611c40b16c50410a609734e 957 Pfam PF01568 Molydopterin dinucleotide binding domain 825 931 9.4E-27 T 12-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 VAPA_1c42240 1804a743f611c40b16c50410a609734e 957 Gene3D G3DSA:3.10.20.740 15 123 6.8E-25 T 12-10-2018 VAPA_1c42240 1804a743f611c40b16c50410a609734e 957 Gene3D G3DSA:3.40.228.10 385 583 2.7E-177 T 12-10-2018 VAPA_1c42240 1804a743f611c40b16c50410a609734e 957 Pfam PF00384 Molybdopterin oxidoreductase 291 733 3.9E-86 T 12-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VAPA_1c42240 1804a743f611c40b16c50410a609734e 957 SUPERFAMILY SSF53706 237 843 2.22E-190 T 12-10-2018 VAPA_1c26680 992b32c73a2b554505a0e7c56cb3a444 475 PIRSF PIRSF006603 29 474 1.7E-100 T 12-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 VAPA_1c26680 992b32c73a2b554505a0e7c56cb3a444 475 Pfam PF01554 MatE 43 202 6.6E-31 T 12-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 VAPA_1c26680 992b32c73a2b554505a0e7c56cb3a444 475 Pfam PF01554 MatE 272 432 3.5E-26 T 12-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 VAPA_1c26680 992b32c73a2b554505a0e7c56cb3a444 475 TIGRFAM TIGR00797 matE: MATE efflux family protein 43 444 1.5E-72 T 12-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 VAPA_1c12930 59b4722dcd171ccd7bdcfc52f1d958e5 243 Gene3D G3DSA:3.40.50.300 2 240 4.4E-55 T 12-10-2018 VAPA_1c12930 59b4722dcd171ccd7bdcfc52f1d958e5 243 SMART SM00382 30 218 9.1E-8 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c12930 59b4722dcd171ccd7bdcfc52f1d958e5 243 Pfam PF00005 ABC transporter 22 167 9.7E-25 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c12930 59b4722dcd171ccd7bdcfc52f1d958e5 243 SUPERFAMILY SSF52540 5 237 8.3E-52 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c12930 59b4722dcd171ccd7bdcfc52f1d958e5 243 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_1c40600 aad66427b7c6df1c6f0d9689af564ee4 260 Gene3D G3DSA:3.40.50.720 1 255 5.4E-57 T 12-10-2018 VAPA_1c40600 aad66427b7c6df1c6f0d9689af564ee4 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 138 146 3.4E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c40600 aad66427b7c6df1c6f0d9689af564ee4 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 3.4E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c40600 aad66427b7c6df1c6f0d9689af564ee4 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 159 178 3.4E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c40600 aad66427b7c6df1c6f0d9689af564ee4 260 SUPERFAMILY SSF51735 1 237 1.62E-57 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c40600 aad66427b7c6df1c6f0d9689af564ee4 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 5.7E-29 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c40600 aad66427b7c6df1c6f0d9689af564ee4 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 159 178 5.7E-29 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c40600 aad66427b7c6df1c6f0d9689af564ee4 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 5.7E-29 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c40600 aad66427b7c6df1c6f0d9689af564ee4 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 208 228 5.7E-29 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c40600 aad66427b7c6df1c6f0d9689af564ee4 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 5.7E-29 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c40600 aad66427b7c6df1c6f0d9689af564ee4 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 180 197 5.7E-29 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c40600 aad66427b7c6df1c6f0d9689af564ee4 260 Pfam PF00106 short chain dehydrogenase 6 200 5.3E-44 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c12580 9c72d3e586a0255e5df4791c8f544083 462 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 7 322 1.4E-18 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 VAPA_2c12580 9c72d3e586a0255e5df4791c8f544083 462 PIRSF PIRSF037495 1 462 1.3E-157 T 12-10-2018 IPR017224 Opine oxidase, subunit A/hydrogen cyanide synthase, subunit B GO:0016491|GO:0055114 VAPA_2c12580 9c72d3e586a0255e5df4791c8f544083 462 Gene3D G3DSA:3.50.50.60 120 264 4.3E-34 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_2c12580 9c72d3e586a0255e5df4791c8f544083 462 Gene3D G3DSA:3.50.50.60 7 320 4.3E-34 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_2c12580 9c72d3e586a0255e5df4791c8f544083 462 Gene3D G3DSA:1.10.10.1100 368 441 6.0E-19 T 12-10-2018 VAPA_2c12580 9c72d3e586a0255e5df4791c8f544083 462 SUPERFAMILY SSF51905 1 331 8.64E-34 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_2c12580 9c72d3e586a0255e5df4791c8f544083 462 ProSitePatterns PS00837 Alanine dehydrogenase & pyridine nucleotide transhydrogenase signature 2. 10 35 - T 12-10-2018 IPR008143 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 GO:0016491|GO:0055114 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1|Reactome: R-HSA-71403 VAPA_2c12580 9c72d3e586a0255e5df4791c8f544083 462 Pfam PF04324 BFD-like [2Fe-2S] binding domain 380 431 9.2E-7 T 12-10-2018 IPR007419 BFD-like [2Fe-2S]-binding domain VAPA_2c12580 9c72d3e586a0255e5df4791c8f544083 462 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 109 117 1.1E-10 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 VAPA_2c12580 9c72d3e586a0255e5df4791c8f544083 462 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 314 333 1.1E-10 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 VAPA_2c12580 9c72d3e586a0255e5df4791c8f544083 462 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 7 29 1.1E-10 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 VAPA_2c12580 9c72d3e586a0255e5df4791c8f544083 462 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 288 310 6.6E-14 T 12-10-2018 VAPA_2c12580 9c72d3e586a0255e5df4791c8f544083 462 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 8 27 6.6E-14 T 12-10-2018 VAPA_2c12580 9c72d3e586a0255e5df4791c8f544083 462 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 108 126 6.6E-14 T 12-10-2018 VAPA_2c12580 9c72d3e586a0255e5df4791c8f544083 462 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 256 272 6.6E-14 T 12-10-2018 VAPA_1c25340 70521387a4ef0fd848731f2720b6a51a 310 SUPERFAMILY SSF51391 104 304 2.88E-53 T 12-10-2018 IPR036206 Thiamin phosphate synthase superfamily KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 VAPA_1c25340 70521387a4ef0fd848731f2720b6a51a 310 Gene3D G3DSA:3.20.20.70 103 308 5.5E-50 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 VAPA_1c25340 70521387a4ef0fd848731f2720b6a51a 310 Pfam PF02581 Thiamine monophosphate synthase 117 288 1.1E-45 T 12-10-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 VAPA_2c02330 13833d16a48a27397bb35dad6cc4262a 309 SUPERFAMILY SSF53850 93 305 1.56E-35 T 12-10-2018 VAPA_2c02330 13833d16a48a27397bb35dad6cc4262a 309 SUPERFAMILY SSF46785 9 111 7.07E-15 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_2c02330 13833d16a48a27397bb35dad6cc4262a 309 Gene3D G3DSA:1.10.10.10 7 93 1.8E-18 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_2c02330 13833d16a48a27397bb35dad6cc4262a 309 Pfam PF03466 LysR substrate binding domain 93 302 8.5E-30 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_2c02330 13833d16a48a27397bb35dad6cc4262a 309 Gene3D G3DSA:3.40.190.10 96 301 6.0E-47 T 12-10-2018 VAPA_2c02330 13833d16a48a27397bb35dad6cc4262a 309 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 9 67 1.4E-12 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_2c02330 13833d16a48a27397bb35dad6cc4262a 309 Gene3D G3DSA:3.40.190.10 169 274 6.0E-47 T 12-10-2018 VAPA_1c46300 fd7e75f682e934a87443dc6e5903791c 477 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 162 175 - T 12-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 VAPA_1c46300 fd7e75f682e934a87443dc6e5903791c 477 Gene3D G3DSA:1.10.10.60 421 467 6.0E-11 T 12-10-2018 VAPA_1c46300 fd7e75f682e934a87443dc6e5903791c 477 Gene3D G3DSA:3.40.50.300 126 310 1.4E-57 T 12-10-2018 VAPA_1c46300 fd7e75f682e934a87443dc6e5903791c 477 SUPERFAMILY SSF52540 139 369 5.45E-53 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c46300 fd7e75f682e934a87443dc6e5903791c 477 Pfam PF00158 Sigma-54 interaction domain 138 305 2.6E-61 T 12-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 VAPA_1c46300 fd7e75f682e934a87443dc6e5903791c 477 SMART SM00382 158 302 3.0E-5 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c46300 fd7e75f682e934a87443dc6e5903791c 477 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 353 362 - T 12-10-2018 IPR025944 Sigma-54 interaction domain, conserved site VAPA_1c46300 fd7e75f682e934a87443dc6e5903791c 477 Pfam PF02954 Bacterial regulatory protein, Fis family 428 464 7.0E-11 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 VAPA_1c46300 fd7e75f682e934a87443dc6e5903791c 477 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 447 467 2.1E-6 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 VAPA_1c46300 fd7e75f682e934a87443dc6e5903791c 477 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 380 397 2.1E-6 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 VAPA_1c46300 fd7e75f682e934a87443dc6e5903791c 477 SUPERFAMILY SSF46689 425 466 5.82E-8 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 VAPA_1c22720 4410eddf5a50519dfa377dcf2d83f5a7 356 SUPERFAMILY SSF53474 108 259 6.55E-13 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c22720 4410eddf5a50519dfa377dcf2d83f5a7 356 Pfam PF07519 Tannase and feruloyl esterase 98 263 3.7E-47 T 12-10-2018 IPR011118 Tannase/feruloyl esterase MetaCyc: PWY-6784 VAPA_1c22720 4410eddf5a50519dfa377dcf2d83f5a7 356 Gene3D G3DSA:3.40.50.1820 94 341 2.0E-9 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c11900 acdb6a8fe92552b5af82c3c01d1d1929 247 Pfam PF01926 50S ribosome-binding GTPase 56 178 1.0E-17 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 VAPA_1c11900 acdb6a8fe92552b5af82c3c01d1d1929 247 Hamap MF_00321 Probable GTP-binding protein EngB [engB]. 42 228 24.475 T 12-10-2018 IPR019987 GTP-binding protein, ribosome biogenesis, YsxC GO:0005525 VAPA_1c11900 acdb6a8fe92552b5af82c3c01d1d1929 247 SUPERFAMILY SSF52540 45 228 3.29E-30 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c11900 acdb6a8fe92552b5af82c3c01d1d1929 247 TIGRFAM TIGR03598 GTPase_YsxC: ribosome biogenesis GTP-binding protein YsxC 37 224 8.1E-60 T 12-10-2018 IPR019987 GTP-binding protein, ribosome biogenesis, YsxC GO:0005525 VAPA_1c11900 acdb6a8fe92552b5af82c3c01d1d1929 247 Gene3D G3DSA:3.40.50.300 30 238 6.3E-49 T 12-10-2018 VAPA_1c50730 6ed1075486d9b29eff9ebe085d78e117 465 PRINTS PR00344 Bacterial sensor protein C-terminal signature 412 422 3.2E-9 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c50730 6ed1075486d9b29eff9ebe085d78e117 465 PRINTS PR00344 Bacterial sensor protein C-terminal signature 429 447 3.2E-9 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c50730 6ed1075486d9b29eff9ebe085d78e117 465 PRINTS PR00344 Bacterial sensor protein C-terminal signature 394 408 3.2E-9 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c50730 6ed1075486d9b29eff9ebe085d78e117 465 Pfam PF00512 His Kinase A (phospho-acceptor) domain 250 308 1.0E-8 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 VAPA_1c50730 6ed1075486d9b29eff9ebe085d78e117 465 Gene3D G3DSA:1.10.287.130 192 304 2.2E-22 T 12-10-2018 VAPA_1c50730 6ed1075486d9b29eff9ebe085d78e117 465 SMART SM00387 352 465 6.0E-27 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase VAPA_1c50730 6ed1075486d9b29eff9ebe085d78e117 465 SMART SM00304 196 248 2.3E-10 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 VAPA_1c50730 6ed1075486d9b29eff9ebe085d78e117 465 Pfam PF00672 HAMP domain 197 244 1.7E-8 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 VAPA_1c50730 6ed1075486d9b29eff9ebe085d78e117 465 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 353 458 2.0E-16 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase VAPA_1c50730 6ed1075486d9b29eff9ebe085d78e117 465 SUPERFAMILY SSF47384 232 310 8.63E-11 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 VAPA_1c50730 6ed1075486d9b29eff9ebe085d78e117 465 Gene3D G3DSA:3.30.565.10 312 465 7.4E-29 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_1c50730 6ed1075486d9b29eff9ebe085d78e117 465 SUPERFAMILY SSF158472 197 246 1.31E-8 T 12-10-2018 VAPA_1c50730 6ed1075486d9b29eff9ebe085d78e117 465 SUPERFAMILY SSF55874 301 464 6.94E-33 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_1c50730 6ed1075486d9b29eff9ebe085d78e117 465 SMART SM00388 249 311 4.8E-8 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 VAPA_1c33390 a74d076ffa8f3a0c7761cf34282bdf1a 192 SUPERFAMILY SSF47616 80 187 7.24E-16 T 12-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily VAPA_1c33390 a74d076ffa8f3a0c7761cf34282bdf1a 192 SUPERFAMILY SSF52833 1 83 1.79E-23 T 12-10-2018 IPR036249 Thioredoxin-like superfamily VAPA_1c33390 a74d076ffa8f3a0c7761cf34282bdf1a 192 Gene3D G3DSA:3.40.30.10 4 187 1.2E-44 T 12-10-2018 VAPA_1c33390 a74d076ffa8f3a0c7761cf34282bdf1a 192 Pfam PF13410 Glutathione S-transferase, C-terminal domain 122 181 1.2E-7 T 12-10-2018 VAPA_1c33390 a74d076ffa8f3a0c7761cf34282bdf1a 192 Pfam PF02798 Glutathione S-transferase, N-terminal domain 4 74 6.9E-16 T 12-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 VAPA_1c33390 a74d076ffa8f3a0c7761cf34282bdf1a 192 Gene3D G3DSA:1.20.1050.10 82 185 1.2E-44 T 12-10-2018 VAPA_1c51950 fbad4cd9f9e51e0968056f914f4fa813 651 Gene3D G3DSA:3.40.50.980 2 256 9.2E-38 T 12-10-2018 VAPA_1c51950 fbad4cd9f9e51e0968056f914f4fa813 651 Gene3D G3DSA:3.40.50.12780 286 472 2.7E-35 T 12-10-2018 VAPA_1c51950 fbad4cd9f9e51e0968056f914f4fa813 651 Pfam PF00501 AMP-binding enzyme 14 476 3.7E-84 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 VAPA_1c51950 fbad4cd9f9e51e0968056f914f4fa813 651 SUPERFAMILY SSF56801 6 610 1.22E-102 T 12-10-2018 VAPA_1c51950 fbad4cd9f9e51e0968056f914f4fa813 651 ProSitePatterns PS00455 Putative AMP-binding domain signature. 191 202 - T 12-10-2018 IPR020845 AMP-binding, conserved site VAPA_2c01020 62d23b703474c3201e76ea7ef5367f52 334 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 60 329 1.9E-74 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_2c01020 62d23b703474c3201e76ea7ef5367f52 334 PIRSF PIRSF017082 1 332 1.4E-77 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_2c01020 62d23b703474c3201e76ea7ef5367f52 334 Gene3D G3DSA:3.40.190.10 137 258 6.6E-105 T 12-10-2018 VAPA_2c01020 62d23b703474c3201e76ea7ef5367f52 334 SUPERFAMILY SSF53850 124 285 1.16E-9 T 12-10-2018 VAPA_2c01020 62d23b703474c3201e76ea7ef5367f52 334 Gene3D G3DSA:3.40.190.150 40 323 6.6E-105 T 12-10-2018 VAPA_1c28770 57102aeaf6931a969879e484676b8b48 103 Pfam PF00550 Phosphopantetheine attachment site 34 96 4.3E-8 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain VAPA_1c28770 57102aeaf6931a969879e484676b8b48 103 SUPERFAMILY SSF47336 18 100 1.57E-9 T 12-10-2018 IPR036736 ACP-like superfamily VAPA_1c28770 57102aeaf6931a969879e484676b8b48 103 Gene3D G3DSA:1.10.1200.10 22 100 2.4E-15 T 12-10-2018 IPR036736 ACP-like superfamily VAPA_1c41040 ca6c520f0a5d08a9937f49515a0401f0 256 SUPERFAMILY SSF161098 53 233 6.8E-27 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c41040 ca6c520f0a5d08a9937f49515a0401f0 256 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 76 233 2.6E-21 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 VAPA_1c41040 ca6c520f0a5d08a9937f49515a0401f0 256 Gene3D G3DSA:1.10.3720.10 49 245 2.2E-23 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c31060 12fca019f9e37215905af8e7d679d64b 608 SMART SM00564 137 169 0.082 T 12-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat VAPA_1c31060 12fca019f9e37215905af8e7d679d64b 608 SMART SM00564 272 320 30.0 T 12-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat VAPA_1c31060 12fca019f9e37215905af8e7d679d64b 608 SMART SM00564 86 118 12.0 T 12-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat VAPA_1c31060 12fca019f9e37215905af8e7d679d64b 608 SMART SM00564 183 220 210.0 T 12-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat VAPA_1c31060 12fca019f9e37215905af8e7d679d64b 608 SUPERFAMILY SSF50998 37 605 2.62E-162 T 12-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily VAPA_1c31060 12fca019f9e37215905af8e7d679d64b 608 TIGRFAM TIGR03075 PQQ_enz_alc_DH: PQQ-dependent dehydrogenase, methanol/ethanol family 26 563 1.1E-220 T 12-10-2018 IPR017512 PQQ-dependent dehydrogenase, methanol/ethanol family GO:0005509|GO:0016020|GO:0016614|GO:0055114 VAPA_1c31060 12fca019f9e37215905af8e7d679d64b 608 Gene3D G3DSA:2.140.10.10 29 606 2.3E-212 T 12-10-2018 VAPA_1c31060 12fca019f9e37215905af8e7d679d64b 608 Pfam PF13360 PQQ-like domain 70 228 1.1E-14 T 12-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat VAPA_1c08060 ce8aa1ab84b7c7e6afc3b5783dfb3fb6 210 Pfam PF01965 DJ-1/PfpI family 2 162 1.1E-15 T 12-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 VAPA_1c08060 ce8aa1ab84b7c7e6afc3b5783dfb3fb6 210 SUPERFAMILY SSF52317 1 176 5.24E-29 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like VAPA_1c08060 ce8aa1ab84b7c7e6afc3b5783dfb3fb6 210 Gene3D G3DSA:3.40.50.880 2 197 2.5E-34 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like VAPA_1c02620 41d8bd31642449ea9276d746970297df 367 Gene3D G3DSA:3.40.47.10 137 346 5.3E-7 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 VAPA_1c02620 41d8bd31642449ea9276d746970297df 367 SUPERFAMILY SSF53901 203 360 6.28E-9 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 VAPA_1c54030 b1003be6462562b5d5135bfab6fd34d8 372 PRINTS PR00142 RecA protein signature 178 207 8.1E-86 T 12-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 VAPA_1c54030 b1003be6462562b5d5135bfab6fd34d8 372 PRINTS PR00142 RecA protein signature 106 135 8.1E-86 T 12-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 VAPA_1c54030 b1003be6462562b5d5135bfab6fd34d8 372 PRINTS PR00142 RecA protein signature 140 169 8.1E-86 T 12-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 VAPA_1c54030 b1003be6462562b5d5135bfab6fd34d8 372 PRINTS PR00142 RecA protein signature 310 327 8.1E-86 T 12-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 VAPA_1c54030 b1003be6462562b5d5135bfab6fd34d8 372 PRINTS PR00142 RecA protein signature 223 251 8.1E-86 T 12-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 VAPA_1c54030 b1003be6462562b5d5135bfab6fd34d8 372 PRINTS PR00142 RecA protein signature 256 285 8.1E-86 T 12-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 VAPA_1c54030 b1003be6462562b5d5135bfab6fd34d8 372 Gene3D G3DSA:3.40.50.300 40 281 1.6E-84 T 12-10-2018 VAPA_1c54030 b1003be6462562b5d5135bfab6fd34d8 372 SMART SM00382 70 241 1.5E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c54030 b1003be6462562b5d5135bfab6fd34d8 372 Pfam PF00154 recA bacterial DNA recombination protein 19 281 1.4E-144 T 12-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 VAPA_1c54030 b1003be6462562b5d5135bfab6fd34d8 372 Hamap MF_00268 Protein RecA [recA]. 17 342 52.106 T 12-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 VAPA_1c54030 b1003be6462562b5d5135bfab6fd34d8 372 SUPERFAMILY SSF54752 281 339 3.66E-22 T 12-10-2018 IPR023400 DNA recombination and repair protein RecA, C-terminal VAPA_1c54030 b1003be6462562b5d5135bfab6fd34d8 372 ProSitePatterns PS00321 recA signature. 226 234 - T 12-10-2018 IPR020584 DNA recombination/repair protein RecA, conserved site GO:0003677|GO:0005524|GO:0006259|GO:0008094 VAPA_1c54030 b1003be6462562b5d5135bfab6fd34d8 372 TIGRFAM TIGR02012 tigrfam_recA: protein RecA 16 337 4.2E-173 T 12-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 VAPA_1c54030 b1003be6462562b5d5135bfab6fd34d8 372 Gene3D G3DSA:3.30.250.10 282 357 1.1E-28 T 12-10-2018 IPR023400 DNA recombination and repair protein RecA, C-terminal VAPA_1c54030 b1003be6462562b5d5135bfab6fd34d8 372 SUPERFAMILY SSF52540 16 280 3.1E-67 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c02070 c285829eeb044ffb2985d7d29867d3f3 915 Gene3D G3DSA:3.40.50.280 428 583 3.0E-52 T 12-10-2018 VAPA_1c02070 c285829eeb044ffb2985d7d29867d3f3 915 Gene3D G3DSA:1.10.288.10 624 786 1.3E-133 T 12-10-2018 VAPA_1c02070 c285829eeb044ffb2985d7d29867d3f3 915 Pfam PF02310 B12 binding domain 433 526 2.1E-16 T 12-10-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 VAPA_1c02070 c285829eeb044ffb2985d7d29867d3f3 915 SUPERFAMILY SSF47644 332 417 5.36E-26 T 12-10-2018 IPR036594 Methionine synthase domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 VAPA_1c02070 c285829eeb044ffb2985d7d29867d3f3 915 SUPERFAMILY SSF52242 428 582 1.27E-40 T 12-10-2018 IPR036724 Cobalamin-binding domain superfamily GO:0031419|GO:0046872 Reactome: R-HSA-196741 VAPA_1c02070 c285829eeb044ffb2985d7d29867d3f3 915 Gene3D G3DSA:3.10.196.10 595 915 1.3E-133 T 12-10-2018 IPR037010 Vitamin B12-dependent methionine synthase, activation domain superfamily GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-7977|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 VAPA_1c02070 c285829eeb044ffb2985d7d29867d3f3 915 PIRSF PIRSF000381 2 888 0.0 T 12-10-2018 IPR011822 Cobalamin-dependent methionine synthase GO:0008270|GO:0008705|GO:0009086|GO:0031419 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-7977|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 VAPA_1c02070 c285829eeb044ffb2985d7d29867d3f3 915 Gene3D G3DSA:1.10.1240.10 319 415 2.2E-35 T 12-10-2018 IPR036594 Methionine synthase domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 VAPA_1c02070 c285829eeb044ffb2985d7d29867d3f3 915 Pfam PF02965 Vitamin B12 dependent methionine synthase, activation domain 625 900 4.8E-119 T 12-10-2018 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-7977|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 VAPA_1c02070 c285829eeb044ffb2985d7d29867d3f3 915 SUPERFAMILY SSF51717 28 302 7.72E-94 T 12-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 VAPA_1c02070 c285829eeb044ffb2985d7d29867d3f3 915 SMART SM01018 331 418 2.5E-40 T 12-10-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 VAPA_1c02070 c285829eeb044ffb2985d7d29867d3f3 915 Gene3D G3DSA:3.20.20.20 12 314 2.3E-131 T 12-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 VAPA_1c02070 c285829eeb044ffb2985d7d29867d3f3 915 Pfam PF02607 B12 binding domain 334 410 2.4E-25 T 12-10-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 VAPA_1c02070 c285829eeb044ffb2985d7d29867d3f3 915 Pfam PF00809 Pterin binding enzyme 32 270 3.7E-61 T 12-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 VAPA_1c02070 c285829eeb044ffb2985d7d29867d3f3 915 TIGRFAM TIGR02082 metH: methionine synthase 9 885 0.0 T 12-10-2018 IPR011822 Cobalamin-dependent methionine synthase GO:0008270|GO:0008705|GO:0009086|GO:0031419 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-7977|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 VAPA_1c02070 c285829eeb044ffb2985d7d29867d3f3 915 SUPERFAMILY SSF56507 590 915 8.24E-123 T 12-10-2018 IPR037010 Vitamin B12-dependent methionine synthase, activation domain superfamily GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-7977|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 VAPA_2c12880 cefad8bc8cd6b88d29f1283cc7f29f20 198 Pfam PF01817 Chorismate mutase type II 40 111 1.1E-5 T 12-10-2018 IPR002701 Chorismate mutase II, prokaryotic-type GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 VAPA_2c12880 cefad8bc8cd6b88d29f1283cc7f29f20 198 SUPERFAMILY SSF48600 40 196 4.27E-28 T 12-10-2018 IPR036263 Chorismate mutase type II superfamily GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 VAPA_2c12880 cefad8bc8cd6b88d29f1283cc7f29f20 198 TIGRFAM TIGR01806 CM_mono2: putative chorismate mutase 38 150 2.4E-24 T 12-10-2018 IPR008240 Chorismate mutase, periplasmic KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 VAPA_2c12880 cefad8bc8cd6b88d29f1283cc7f29f20 198 SMART SM00830 39 114 2.6E-9 T 12-10-2018 IPR002701 Chorismate mutase II, prokaryotic-type GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 VAPA_2c12880 cefad8bc8cd6b88d29f1283cc7f29f20 198 Gene3D G3DSA:1.20.1250.110 27 198 9.4E-55 T 12-10-2018 VAPA_1c24130 3e267a9a3e7ff51cd8b4e45f7695cb94 275 Pfam PF00378 Enoyl-CoA hydratase/isomerase 11 272 3.4E-38 T 12-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 VAPA_1c24130 3e267a9a3e7ff51cd8b4e45f7695cb94 275 SUPERFAMILY SSF52096 4 273 1.61E-68 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily VAPA_1c24130 3e267a9a3e7ff51cd8b4e45f7695cb94 275 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 117 137 - T 12-10-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824 VAPA_1c24130 3e267a9a3e7ff51cd8b4e45f7695cb94 275 Gene3D G3DSA:1.10.12.10 217 274 4.3E-22 T 12-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal VAPA_1c24130 3e267a9a3e7ff51cd8b4e45f7695cb94 275 Gene3D G3DSA:3.90.226.10 1 216 4.6E-65 T 12-10-2018 VAPA_1c04070 16822a8e74206a09a8ba9c2b3b8053ae 377 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 43 163 2.8E-25 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 VAPA_1c04070 16822a8e74206a09a8ba9c2b3b8053ae 377 SUPERFAMILY SSF50129 19 205 6.18E-45 T 12-10-2018 IPR011032 GroES-like superfamily VAPA_1c04070 16822a8e74206a09a8ba9c2b3b8053ae 377 Pfam PF00107 Zinc-binding dehydrogenase 206 333 2.6E-21 T 12-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 VAPA_1c04070 16822a8e74206a09a8ba9c2b3b8053ae 377 SUPERFAMILY SSF51735 173 331 2.41E-37 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c04070 16822a8e74206a09a8ba9c2b3b8053ae 377 SMART SM00829 27 370 0.0019 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 VAPA_1c04070 16822a8e74206a09a8ba9c2b3b8053ae 377 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 86 100 - T 12-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 VAPA_1c04070 16822a8e74206a09a8ba9c2b3b8053ae 377 Gene3D G3DSA:3.90.180.10 27 359 1.4E-95 T 12-10-2018 VAPA_1c04070 16822a8e74206a09a8ba9c2b3b8053ae 377 Gene3D G3DSA:3.40.50.720 183 320 1.4E-95 T 12-10-2018 VAPA_1c37310 5b97844007c674e08bf5067b5beff1fa 438 Pfam PF13533 Biotin-lipoyl like 103 148 1.3E-9 T 12-10-2018 IPR039562 Membrane fusion protein, biotin-lipoyl like domain VAPA_1c37310 5b97844007c674e08bf5067b5beff1fa 438 Pfam PF13437 HlyD family secretion protein 213 314 3.8E-5 T 12-10-2018 VAPA_1c37310 5b97844007c674e08bf5067b5beff1fa 438 Gene3D G3DSA:2.40.30.170 95 314 8.9E-59 T 12-10-2018 VAPA_1c37310 5b97844007c674e08bf5067b5beff1fa 438 SUPERFAMILY SSF111369 90 328 7.45E-51 T 12-10-2018 VAPA_1c37310 5b97844007c674e08bf5067b5beff1fa 438 Gene3D G3DSA:1.10.287.470 136 209 8.9E-59 T 12-10-2018 VAPA_1c37310 5b97844007c674e08bf5067b5beff1fa 438 Gene3D G3DSA:2.40.420.20 315 405 1.0E-19 T 12-10-2018 VAPA_1c37310 5b97844007c674e08bf5067b5beff1fa 438 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 80 404 1.4E-71 T 12-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 VAPA_1c37310 5b97844007c674e08bf5067b5beff1fa 438 Gene3D G3DSA:2.40.50.100 101 245 8.9E-59 T 12-10-2018 VAPA_1c31380 11e92d34505cff77e2e0233c0b51bfbc 194 Pfam PF04289 Protein of unknown function (DUF447) 7 178 2.7E-48 T 12-10-2018 IPR007386 Protein of unknown function DUF447 VAPA_1c31380 11e92d34505cff77e2e0233c0b51bfbc 194 SUPERFAMILY SSF50475 3 181 2.66E-55 T 12-10-2018 VAPA_1c31380 11e92d34505cff77e2e0233c0b51bfbc 194 Gene3D G3DSA:1.20.58.290 64 177 1.1E-57 T 12-10-2018 VAPA_1c31380 11e92d34505cff77e2e0233c0b51bfbc 194 Gene3D G3DSA:2.30.110.10 5 128 1.1E-57 T 12-10-2018 IPR012349 FMN-binding split barrel GO:0048037 VAPA_2c10180 0885101c70e2516e1d37ce9eb42c6e60 280 SUPERFAMILY SSF103088 154 276 1.96E-28 T 12-10-2018 IPR036737 OmpA-like domain superfamily VAPA_2c10180 0885101c70e2516e1d37ce9eb42c6e60 280 PRINTS PR01021 OMPA domain signature 199 214 3.1E-12 T 12-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 VAPA_2c10180 0885101c70e2516e1d37ce9eb42c6e60 280 PRINTS PR01021 OMPA domain signature 167 189 3.1E-12 T 12-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 VAPA_2c10180 0885101c70e2516e1d37ce9eb42c6e60 280 PRINTS PR01021 OMPA domain signature 214 230 3.1E-12 T 12-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 VAPA_2c10180 0885101c70e2516e1d37ce9eb42c6e60 280 Gene3D G3DSA:3.30.1330.60 141 280 3.2E-39 T 12-10-2018 IPR036737 OmpA-like domain superfamily VAPA_2c10180 0885101c70e2516e1d37ce9eb42c6e60 280 Pfam PF00691 OmpA family 171 261 1.7E-19 T 12-10-2018 IPR006665 OmpA-like domain VAPA_2c10180 0885101c70e2516e1d37ce9eb42c6e60 280 Gene3D G3DSA:3.30.1450.10 54 131 4.4E-8 T 12-10-2018 IPR037873 BamE-like VAPA_2c10180 0885101c70e2516e1d37ce9eb42c6e60 280 Pfam PF04355 SmpA / OmlA family 55 119 7.7E-16 T 12-10-2018 IPR007450 Lipoprotein SmpA/OmlA GO:0019867 VAPA_1c08790 51530267f235ddd22ff5785d52778302 197 PIRSF PIRSF006386 1 197 7.6E-70 T 12-10-2018 IPR014440 HCCA isomerase/glutathione S-transferase kappa Reactome: R-HSA-156590|Reactome: R-HSA-9033241 VAPA_1c08790 51530267f235ddd22ff5785d52778302 197 Gene3D G3DSA:3.40.30.10 4 197 3.2E-70 T 12-10-2018 VAPA_1c08790 51530267f235ddd22ff5785d52778302 197 SUPERFAMILY SSF52833 1 196 1.79E-48 T 12-10-2018 IPR036249 Thioredoxin-like superfamily VAPA_1c08790 51530267f235ddd22ff5785d52778302 197 Pfam PF01323 DSBA-like thioredoxin domain 4 195 3.7E-43 T 12-10-2018 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590|Reactome: R-HSA-9033241 VAPA_1c25950 9869375931976b3239895a9a9861e35f 167 Pfam PF02600 Disulfide bond formation protein DsbB 10 158 1.2E-42 T 12-10-2018 IPR003752 Disulphide bond formation protein DsbB/BdbC GO:0015035|GO:0016020 VAPA_1c25950 9869375931976b3239895a9a9861e35f 167 SUPERFAMILY SSF158442 14 159 5.23E-41 T 12-10-2018 IPR023380 DsbB-like superfamily VAPA_1c25950 9869375931976b3239895a9a9861e35f 167 Hamap MF_00286 Disulfide bond formation protein B [dsbB]. 5 166 21.679 T 12-10-2018 IPR022920 Disulphide bond formation protein DsbB VAPA_1c25950 9869375931976b3239895a9a9861e35f 167 Gene3D G3DSA:1.20.1550.10 5 166 2.3E-46 T 12-10-2018 IPR023380 DsbB-like superfamily VAPA_1c17320 5e99aa8384ad6a37c61b18f6c525529f 247 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 67 231 6.0E-39 T 12-10-2018 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 VAPA_1c17320 5e99aa8384ad6a37c61b18f6c525529f 247 SUPERFAMILY SSF55120 61 235 8.64E-41 T 12-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 VAPA_1c17320 5e99aa8384ad6a37c61b18f6c525529f 247 Gene3D G3DSA:3.10.290.10 1 54 5.7E-6 T 12-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 VAPA_1c17320 5e99aa8384ad6a37c61b18f6c525529f 247 Gene3D G3DSA:3.30.70.1560 136 217 1.1E-48 T 12-10-2018 VAPA_1c17320 5e99aa8384ad6a37c61b18f6c525529f 247 Pfam PF01479 S4 domain 3 37 2.1E-6 T 12-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VAPA_1c17320 5e99aa8384ad6a37c61b18f6c525529f 247 SUPERFAMILY SSF55174 1 90 1.06E-11 T 12-10-2018 VAPA_1c17320 5e99aa8384ad6a37c61b18f6c525529f 247 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 107 121 - T 12-10-2018 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 VAPA_1c17320 5e99aa8384ad6a37c61b18f6c525529f 247 Gene3D G3DSA:3.30.70.580 62 235 1.1E-48 T 12-10-2018 VAPA_1c17320 5e99aa8384ad6a37c61b18f6c525529f 247 Pfam PF00849 RNA pseudouridylate synthase 62 200 7.3E-13 T 12-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 VAPA_1c24750 a7a7db71f02d8db2fc2cfe2c116907a0 277 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 95 264 2.8E-23 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 VAPA_1c24750 a7a7db71f02d8db2fc2cfe2c116907a0 277 SUPERFAMILY SSF161098 72 254 3.79E-28 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c24750 a7a7db71f02d8db2fc2cfe2c116907a0 277 Gene3D G3DSA:1.10.3720.10 72 266 9.0E-22 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_2c01070 d500319ed6f75dec2941fd647a0e0093 384 Gene3D G3DSA:1.20.140.10 238 384 2.2E-47 T 12-10-2018 VAPA_2c01070 d500319ed6f75dec2941fd647a0e0093 384 Gene3D G3DSA:2.40.110.10 123 237 1.6E-38 T 12-10-2018 VAPA_2c01070 d500319ed6f75dec2941fd647a0e0093 384 Gene3D G3DSA:1.10.540.10 2 121 1.9E-37 T 12-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 VAPA_2c01070 d500319ed6f75dec2941fd647a0e0093 384 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 233 381 7.6E-45 T 12-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 VAPA_2c01070 d500319ed6f75dec2941fd647a0e0093 384 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 124 220 6.3E-25 T 12-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 VAPA_2c01070 d500319ed6f75dec2941fd647a0e0093 384 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 340 359 - T 12-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 VAPA_2c01070 d500319ed6f75dec2941fd647a0e0093 384 SUPERFAMILY SSF56645 5 245 7.98E-82 T 12-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 VAPA_2c01070 d500319ed6f75dec2941fd647a0e0093 384 SUPERFAMILY SSF47203 231 383 4.19E-50 T 12-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 VAPA_2c01070 d500319ed6f75dec2941fd647a0e0093 384 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 9 120 1.8E-34 T 12-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 VAPA_1c26930 5391816b48cc0fe448388493a8e1023e 292 SUPERFAMILY SSF55729 155 291 1.12E-34 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase VAPA_1c26930 5391816b48cc0fe448388493a8e1023e 292 Gene3D G3DSA:3.10.129.10 2 143 3.2E-35 T 12-10-2018 VAPA_1c26930 5391816b48cc0fe448388493a8e1023e 292 Pfam PF03061 Thioesterase superfamily 29 112 4.5E-13 T 12-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 VAPA_1c26930 5391816b48cc0fe448388493a8e1023e 292 Gene3D G3DSA:3.40.630.30 151 291 1.5E-35 T 12-10-2018 VAPA_1c26930 5391816b48cc0fe448388493a8e1023e 292 SUPERFAMILY SSF54637 8 143 2.62E-39 T 12-10-2018 IPR029069 HotDog domain superfamily VAPA_1c26930 5391816b48cc0fe448388493a8e1023e 292 TIGRFAM TIGR00051 TIGR00051: acyl-CoA thioester hydrolase, YbgC/YbaW family 17 128 9.0E-25 T 12-10-2018 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 VAPA_1c26930 5391816b48cc0fe448388493a8e1023e 292 Pfam PF13673 Acetyltransferase (GNAT) domain 172 290 1.0E-16 T 12-10-2018 IPR000182 GNAT domain VAPA_1c21880 871b09e0d39cfb4f16dc8fddab956385 533 Pfam PF01144 Coenzyme A transferase 8 241 6.4E-27 T 12-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 VAPA_1c21880 871b09e0d39cfb4f16dc8fddab956385 533 PIRSF PIRSF000858 1 519 6.4E-203 T 12-10-2018 IPR014388 3-oxoacid CoA-transferase GO:0008410|GO:0046952 Reactome: R-HSA-77108 VAPA_1c21880 871b09e0d39cfb4f16dc8fddab956385 533 SUPERFAMILY SSF100950 272 513 1.09E-66 T 12-10-2018 IPR037171 NagB/RpiA transferase-like VAPA_1c21880 871b09e0d39cfb4f16dc8fddab956385 533 SUPERFAMILY SSF100950 5 256 1.32E-74 T 12-10-2018 IPR037171 NagB/RpiA transferase-like VAPA_1c21880 871b09e0d39cfb4f16dc8fddab956385 533 SMART SM00882 4 242 4.1E-53 T 12-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 VAPA_1c21880 871b09e0d39cfb4f16dc8fddab956385 533 Gene3D G3DSA:3.40.1080.10 2 263 1.7E-91 T 12-10-2018 VAPA_1c21880 871b09e0d39cfb4f16dc8fddab956385 533 Gene3D G3DSA:3.40.1080.10 272 519 3.4E-95 T 12-10-2018 VAPA_2c06620 6cbe54aadac777de0f094b364b17b062 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 1.1E-33 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c06620 6cbe54aadac777de0f094b364b17b062 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 1.1E-33 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c06620 6cbe54aadac777de0f094b364b17b062 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 1.1E-33 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c06620 6cbe54aadac777de0f094b364b17b062 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 1.1E-33 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c06620 6cbe54aadac777de0f094b364b17b062 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 1.1E-33 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c06620 6cbe54aadac777de0f094b364b17b062 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 214 234 1.1E-33 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c06620 6cbe54aadac777de0f094b364b17b062 258 SUPERFAMILY SSF51735 6 252 1.15E-69 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_2c06620 6cbe54aadac777de0f094b364b17b062 258 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 17 251 9.7E-50 T 12-10-2018 VAPA_2c06620 6cbe54aadac777de0f094b364b17b062 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 3.7E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c06620 6cbe54aadac777de0f094b364b17b062 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 141 3.7E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c06620 6cbe54aadac777de0f094b364b17b062 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 3.7E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c06620 6cbe54aadac777de0f094b364b17b062 258 Gene3D G3DSA:3.40.50.720 1 258 2.2E-76 T 12-10-2018 VAPA_1c20960 267de47ec1fc372508623cf599edd5b2 361 Gene3D G3DSA:1.20.1530.20 17 349 2.5E-15 T 12-10-2018 IPR038770 Sodium/solute symporter superfamily VAPA_1c20960 267de47ec1fc372508623cf599edd5b2 361 PIRSF PIRSF005508 3 360 1.0E-116 T 12-10-2018 IPR004706 Arsenical-resistance protein Acr3 GO:0015103|GO:0015297|GO:0016021 VAPA_1c20960 267de47ec1fc372508623cf599edd5b2 361 TIGRFAM TIGR00832 acr3: arsenical-resistance protein 20 346 1.4E-116 T 12-10-2018 IPR004706 Arsenical-resistance protein Acr3 GO:0015103|GO:0015297|GO:0016021 VAPA_1c20960 267de47ec1fc372508623cf599edd5b2 361 Pfam PF01758 Sodium Bile acid symporter family 66 259 2.2E-35 T 12-10-2018 IPR002657 Bile acid:sodium symporter/arsenical resistance protein Acr3 GO:0016020 VAPA_1c16590 1f4af320fd58812a6423a12fbb0b7a5e 237 Gene3D G3DSA:3.40.50.300 3 227 6.5E-55 T 12-10-2018 VAPA_1c16590 1f4af320fd58812a6423a12fbb0b7a5e 237 Pfam PF00005 ABC transporter 27 178 7.0E-29 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c16590 1f4af320fd58812a6423a12fbb0b7a5e 237 SMART SM00382 31 226 7.3E-14 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c16590 1f4af320fd58812a6423a12fbb0b7a5e 237 SUPERFAMILY SSF52540 4 221 7.42E-49 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_2c05090 9a17814f4b860b37314d07b68021a1ea 2011 SUPERFAMILY SSF101967 926 1042 1.44E-16 T 12-10-2018 VAPA_2c05090 9a17814f4b860b37314d07b68021a1ea 2011 SUPERFAMILY SSF101967 1052 1166 9.81E-16 T 12-10-2018 VAPA_2c05090 9a17814f4b860b37314d07b68021a1ea 2011 Gene3D G3DSA:1.20.5.170 745 767 5.7E-13 T 12-10-2018 VAPA_2c05090 9a17814f4b860b37314d07b68021a1ea 2011 Gene3D G3DSA:2.150.10.10 620 744 2.2E-20 T 12-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal VAPA_2c05090 9a17814f4b860b37314d07b68021a1ea 2011 SUPERFAMILY SSF101967 1573 1690 3.66E-16 T 12-10-2018 VAPA_2c05090 9a17814f4b860b37314d07b68021a1ea 2011 SUPERFAMILY SSF101967 63 165 2.48E-10 T 12-10-2018 VAPA_2c05090 9a17814f4b860b37314d07b68021a1ea 2011 SUPERFAMILY SSF101967 146 332 5.62E-12 T 12-10-2018 VAPA_2c05090 9a17814f4b860b37314d07b68021a1ea 2011 SUPERFAMILY SSF101967 787 904 1.05E-15 T 12-10-2018 VAPA_2c05090 9a17814f4b860b37314d07b68021a1ea 2011 Pfam PF05658 Head domain of trimeric autotransporter adhesin 1074 1100 1.6E-4 T 12-10-2018 IPR008640 Head domain of trimeric autotransporter adhesin GO:0009405|GO:0019867 VAPA_2c05090 9a17814f4b860b37314d07b68021a1ea 2011 Pfam PF05658 Head domain of trimeric autotransporter adhesin 1598 1624 6.9E-6 T 12-10-2018 IPR008640 Head domain of trimeric autotransporter adhesin GO:0009405|GO:0019867 VAPA_2c05090 9a17814f4b860b37314d07b68021a1ea 2011 Pfam PF05658 Head domain of trimeric autotransporter adhesin 1336 1362 3.8E-5 T 12-10-2018 IPR008640 Head domain of trimeric autotransporter adhesin GO:0009405|GO:0019867 VAPA_2c05090 9a17814f4b860b37314d07b68021a1ea 2011 Pfam PF05658 Head domain of trimeric autotransporter adhesin 950 976 4.2E-5 T 12-10-2018 IPR008640 Head domain of trimeric autotransporter adhesin GO:0009405|GO:0019867 VAPA_2c05090 9a17814f4b860b37314d07b68021a1ea 2011 Pfam PF05658 Head domain of trimeric autotransporter adhesin 1467 1493 1.4E-5 T 12-10-2018 IPR008640 Head domain of trimeric autotransporter adhesin GO:0009405|GO:0019867 VAPA_2c05090 9a17814f4b860b37314d07b68021a1ea 2011 Pfam PF05658 Head domain of trimeric autotransporter adhesin 550 576 1.2E-5 T 12-10-2018 IPR008640 Head domain of trimeric autotransporter adhesin GO:0009405|GO:0019867 VAPA_2c05090 9a17814f4b860b37314d07b68021a1ea 2011 Pfam PF05658 Head domain of trimeric autotransporter adhesin 180 206 1.5E-4 T 12-10-2018 IPR008640 Head domain of trimeric autotransporter adhesin GO:0009405|GO:0019867 VAPA_2c05090 9a17814f4b860b37314d07b68021a1ea 2011 Pfam PF05658 Head domain of trimeric autotransporter adhesin 1205 1231 1.0E-4 T 12-10-2018 IPR008640 Head domain of trimeric autotransporter adhesin GO:0009405|GO:0019867 VAPA_2c05090 9a17814f4b860b37314d07b68021a1ea 2011 Pfam PF05658 Head domain of trimeric autotransporter adhesin 497 522 1.1E-4 T 12-10-2018 IPR008640 Head domain of trimeric autotransporter adhesin GO:0009405|GO:0019867 VAPA_2c05090 9a17814f4b860b37314d07b68021a1ea 2011 Pfam PF05658 Head domain of trimeric autotransporter adhesin 812 838 1.6E-4 T 12-10-2018 IPR008640 Head domain of trimeric autotransporter adhesin GO:0009405|GO:0019867 VAPA_2c05090 9a17814f4b860b37314d07b68021a1ea 2011 SUPERFAMILY SSF101967 1311 1428 1.7E-16 T 12-10-2018 VAPA_2c05090 9a17814f4b860b37314d07b68021a1ea 2011 SUPERFAMILY SSF101967 1707 1812 1.07E-10 T 12-10-2018 VAPA_2c05090 9a17814f4b860b37314d07b68021a1ea 2011 SUPERFAMILY SSF101967 377 536 4.45E-12 T 12-10-2018 VAPA_2c05090 9a17814f4b860b37314d07b68021a1ea 2011 Gene3D G3DSA:2.150.10.10 44 138 2.9E-6 T 12-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal VAPA_2c05090 9a17814f4b860b37314d07b68021a1ea 2011 Gene3D G3DSA:2.150.10.10 139 250 6.3E-14 T 12-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal VAPA_2c05090 9a17814f4b860b37314d07b68021a1ea 2011 Gene3D G3DSA:2.150.10.10 470 604 2.4E-16 T 12-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal VAPA_2c05090 9a17814f4b860b37314d07b68021a1ea 2011 Gene3D G3DSA:2.150.10.10 251 372 4.8E-7 T 12-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal VAPA_2c05090 9a17814f4b860b37314d07b68021a1ea 2011 SUPERFAMILY SSF101967 1443 1559 9.68E-17 T 12-10-2018 VAPA_2c05090 9a17814f4b860b37314d07b68021a1ea 2011 Pfam PF05662 Coiled stalk of trimeric autotransporter adhesin 1532 1576 2.9E-12 T 12-10-2018 IPR008635 Coiled stalk of trimeric autotransporter adhesin GO:0009405|GO:0019867 VAPA_2c05090 9a17814f4b860b37314d07b68021a1ea 2011 Pfam PF05662 Coiled stalk of trimeric autotransporter adhesin 1139 1182 2.9E-13 T 12-10-2018 IPR008635 Coiled stalk of trimeric autotransporter adhesin GO:0009405|GO:0019867 VAPA_2c05090 9a17814f4b860b37314d07b68021a1ea 2011 Pfam PF05662 Coiled stalk of trimeric autotransporter adhesin 1791 1813 6.9E-7 T 12-10-2018 IPR008635 Coiled stalk of trimeric autotransporter adhesin GO:0009405|GO:0019867 VAPA_2c05090 9a17814f4b860b37314d07b68021a1ea 2011 Pfam PF05662 Coiled stalk of trimeric autotransporter adhesin 1401 1445 2.5E-12 T 12-10-2018 IPR008635 Coiled stalk of trimeric autotransporter adhesin GO:0009405|GO:0019867 VAPA_2c05090 9a17814f4b860b37314d07b68021a1ea 2011 Pfam PF05662 Coiled stalk of trimeric autotransporter adhesin 1663 1703 1.2E-13 T 12-10-2018 IPR008635 Coiled stalk of trimeric autotransporter adhesin GO:0009405|GO:0019867 VAPA_2c05090 9a17814f4b860b37314d07b68021a1ea 2011 Pfam PF05662 Coiled stalk of trimeric autotransporter adhesin 1270 1314 5.4E-13 T 12-10-2018 IPR008635 Coiled stalk of trimeric autotransporter adhesin GO:0009405|GO:0019867 VAPA_2c05090 9a17814f4b860b37314d07b68021a1ea 2011 Pfam PF05662 Coiled stalk of trimeric autotransporter adhesin 1015 1058 8.5E-14 T 12-10-2018 IPR008635 Coiled stalk of trimeric autotransporter adhesin GO:0009405|GO:0019867 VAPA_2c05090 9a17814f4b860b37314d07b68021a1ea 2011 Pfam PF05662 Coiled stalk of trimeric autotransporter adhesin 739 783 7.5E-13 T 12-10-2018 IPR008635 Coiled stalk of trimeric autotransporter adhesin GO:0009405|GO:0019867 VAPA_2c05090 9a17814f4b860b37314d07b68021a1ea 2011 Pfam PF05662 Coiled stalk of trimeric autotransporter adhesin 877 921 8.4E-13 T 12-10-2018 IPR008635 Coiled stalk of trimeric autotransporter adhesin GO:0009405|GO:0019867 VAPA_2c05090 9a17814f4b860b37314d07b68021a1ea 2011 Pfam PF05662 Coiled stalk of trimeric autotransporter adhesin 1966 2005 8.5E-9 T 12-10-2018 IPR008635 Coiled stalk of trimeric autotransporter adhesin GO:0009405|GO:0019867 VAPA_2c05090 9a17814f4b860b37314d07b68021a1ea 2011 SUPERFAMILY SSF101967 1833 1988 5.49E-20 T 12-10-2018 VAPA_2c05090 9a17814f4b860b37314d07b68021a1ea 2011 Gene3D G3DSA:2.150.10.10 1428 1558 5.2E-38 T 12-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal VAPA_2c05090 9a17814f4b860b37314d07b68021a1ea 2011 Gene3D G3DSA:2.150.10.10 1166 1297 3.7E-38 T 12-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal VAPA_2c05090 9a17814f4b860b37314d07b68021a1ea 2011 Gene3D G3DSA:2.150.10.10 1559 1689 6.9E-39 T 12-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal VAPA_2c05090 9a17814f4b860b37314d07b68021a1ea 2011 Gene3D G3DSA:2.150.10.10 1043 1165 5.5E-37 T 12-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal VAPA_2c05090 9a17814f4b860b37314d07b68021a1ea 2011 Gene3D G3DSA:2.150.10.10 768 904 1.0E-39 T 12-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal VAPA_2c05090 9a17814f4b860b37314d07b68021a1ea 2011 Gene3D G3DSA:2.150.10.10 1298 1427 3.4E-39 T 12-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal VAPA_2c05090 9a17814f4b860b37314d07b68021a1ea 2011 Gene3D G3DSA:2.150.10.10 905 1042 9.0E-40 T 12-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal VAPA_2c05090 9a17814f4b860b37314d07b68021a1ea 2011 Gene3D G3DSA:2.150.10.10 1690 1814 5.2E-17 T 12-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal VAPA_2c05090 9a17814f4b860b37314d07b68021a1ea 2011 Pfam PF13018 Extended Signal Peptide of Type V secretion system 1 24 7.1E-11 T 12-10-2018 IPR024973 ESPR domain VAPA_2c05090 9a17814f4b860b37314d07b68021a1ea 2011 SUPERFAMILY SSF101967 649 766 1.44E-19 T 12-10-2018 VAPA_2c05090 9a17814f4b860b37314d07b68021a1ea 2011 Gene3D G3DSA:2.150.10.10 1895 2009 1.6E-20 T 12-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal VAPA_2c05090 9a17814f4b860b37314d07b68021a1ea 2011 Gene3D G3DSA:2.150.10.10 1823 1894 1.1E-15 T 12-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal VAPA_2c05090 9a17814f4b860b37314d07b68021a1ea 2011 SUPERFAMILY SSF101967 1180 1297 5.89E-16 T 12-10-2018 VAPA_2c05090 9a17814f4b860b37314d07b68021a1ea 2011 Gene3D G3DSA:2.150.10.10 373 469 2.0E-10 T 12-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal VAPA_2c05090 9a17814f4b860b37314d07b68021a1ea 2011 SUPERFAMILY SSF101967 548 672 6.54E-19 T 12-10-2018 VAPA_1c09280 5c2dd26b1c576d33b984f74e22bf6dcd 159 ProSitePatterns PS01117 MarR-type HTH domain signature. 72 106 - T 12-10-2018 IPR023187 Transcriptional regulator MarR-type, conserved site VAPA_1c09280 5c2dd26b1c576d33b984f74e22bf6dcd 159 Pfam PF13463 Winged helix DNA-binding domain 48 106 4.2E-11 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 VAPA_1c09280 5c2dd26b1c576d33b984f74e22bf6dcd 159 SMART SM00347 32 133 2.1E-14 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 VAPA_1c09280 5c2dd26b1c576d33b984f74e22bf6dcd 159 SUPERFAMILY SSF46785 14 146 7.31E-28 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c09280 5c2dd26b1c576d33b984f74e22bf6dcd 159 Gene3D G3DSA:1.10.10.10 8 143 3.2E-30 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c09280 5c2dd26b1c576d33b984f74e22bf6dcd 159 PRINTS PR00598 Bacterial regulatory protein MarR family signature 93 109 5.4E-10 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 VAPA_1c09280 5c2dd26b1c576d33b984f74e22bf6dcd 159 PRINTS PR00598 Bacterial regulatory protein MarR family signature 74 89 5.4E-10 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 VAPA_1c09280 5c2dd26b1c576d33b984f74e22bf6dcd 159 PRINTS PR00598 Bacterial regulatory protein MarR family signature 57 73 5.4E-10 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 VAPA_2c01510 1fbeb9f9ee461f6dd3b2d54f2b4a5ea8 301 SUPERFAMILY SSF48179 169 273 1.79E-29 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 VAPA_2c01510 1fbeb9f9ee461f6dd3b2d54f2b4a5ea8 301 Pfam PF09130 Domain of unknown function (DUF1932) 196 267 6.1E-18 T 12-10-2018 IPR015814 Phosphogluconate dehydrogenase, NAD-binding, putative, C-terminal VAPA_2c01510 1fbeb9f9ee461f6dd3b2d54f2b4a5ea8 301 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 5 128 8.7E-6 T 12-10-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 VAPA_2c01510 1fbeb9f9ee461f6dd3b2d54f2b4a5ea8 301 Gene3D G3DSA:3.40.50.720 5 175 6.4E-30 T 12-10-2018 VAPA_2c01510 1fbeb9f9ee461f6dd3b2d54f2b4a5ea8 301 Gene3D G3DSA:1.10.1040.10 177 293 8.5E-37 T 12-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 VAPA_2c01510 1fbeb9f9ee461f6dd3b2d54f2b4a5ea8 301 SUPERFAMILY SSF51735 5 167 7.99E-32 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_2c02500 9da5f0ce5b7bc386dc87219f11c4ca20 298 SUPERFAMILY SSF46785 12 92 2.23E-18 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_2c02500 9da5f0ce5b7bc386dc87219f11c4ca20 298 Gene3D G3DSA:3.40.190.10 106 291 1.4E-44 T 12-10-2018 VAPA_2c02500 9da5f0ce5b7bc386dc87219f11c4ca20 298 Gene3D G3DSA:3.40.190.10 166 264 1.4E-44 T 12-10-2018 VAPA_2c02500 9da5f0ce5b7bc386dc87219f11c4ca20 298 SUPERFAMILY SSF53850 95 297 4.71E-28 T 12-10-2018 VAPA_2c02500 9da5f0ce5b7bc386dc87219f11c4ca20 298 Pfam PF03466 LysR substrate binding domain 94 295 1.9E-27 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_2c02500 9da5f0ce5b7bc386dc87219f11c4ca20 298 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 13 69 9.2E-17 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_2c02500 9da5f0ce5b7bc386dc87219f11c4ca20 298 Gene3D G3DSA:1.10.10.10 9 96 3.7E-20 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_2c02500 9da5f0ce5b7bc386dc87219f11c4ca20 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 46 57 1.8E-9 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_2c02500 9da5f0ce5b7bc386dc87219f11c4ca20 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 36 46 1.8E-9 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_2c02500 9da5f0ce5b7bc386dc87219f11c4ca20 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 25 36 1.8E-9 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c46360 8553c2561efbce7e433f8b386f9eaeaf 167 TIGRFAM TIGR02802 Pal_lipo: peptidoglycan-associated lipoprotein 64 166 1.6E-37 T 12-10-2018 IPR014169 Peptidoglycan-associated lipoprotein, C-terminal GO:0009279 VAPA_1c46360 8553c2561efbce7e433f8b386f9eaeaf 167 Gene3D G3DSA:3.30.1330.60 51 167 2.5E-37 T 12-10-2018 IPR036737 OmpA-like domain superfamily VAPA_1c46360 8553c2561efbce7e433f8b386f9eaeaf 167 ProSitePatterns PS01068 OmpA-like domain. 98 142 - T 12-10-2018 IPR006690 Outer membrane protein, OmpA-like, conserved site GO:0009279|GO:0016021 VAPA_1c46360 8553c2561efbce7e433f8b386f9eaeaf 167 Pfam PF00691 OmpA family 65 160 2.7E-23 T 12-10-2018 IPR006665 OmpA-like domain VAPA_1c46360 8553c2561efbce7e433f8b386f9eaeaf 167 SUPERFAMILY SSF103088 44 165 7.06E-34 T 12-10-2018 IPR036737 OmpA-like domain superfamily VAPA_1c46360 8553c2561efbce7e433f8b386f9eaeaf 167 PRINTS PR01021 OMPA domain signature 96 111 7.1E-18 T 12-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 VAPA_1c46360 8553c2561efbce7e433f8b386f9eaeaf 167 PRINTS PR01021 OMPA domain signature 66 88 7.1E-18 T 12-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 VAPA_1c46360 8553c2561efbce7e433f8b386f9eaeaf 167 PRINTS PR01021 OMPA domain signature 111 127 7.1E-18 T 12-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 VAPA_1c46360 8553c2561efbce7e433f8b386f9eaeaf 167 Hamap MF_02204 Peptidoglycan-associated lipoprotein [pal]. 2 166 27.502 T 12-10-2018 IPR039001 Peptidoglycan-associated lipoprotein GO:0009279|GO:0051301 VAPA_2c12920 ab8db37602058d70dc214303373431f5 247 Gene3D G3DSA:1.10.3290.10 6 192 8.1E-29 T 12-10-2018 IPR036597 Fido-like domain superfamily VAPA_2c12920 ab8db37602058d70dc214303373431f5 247 Pfam PF02661 Fic/DOC family 53 144 3.1E-11 T 12-10-2018 IPR003812 Fido domain VAPA_2c12920 ab8db37602058d70dc214303373431f5 247 SUPERFAMILY SSF140931 30 172 2.62E-24 T 12-10-2018 IPR036597 Fido-like domain superfamily VAPA_1c41970 29f59d534d1b39ebe88a41d1d27588bf 285 Pfam PF02104 SURF1 family 33 242 1.3E-42 T 12-10-2018 IPR002994 Surfeit locus 1/Shy1 GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 VAPA_1c52370 dd875480d921b8a3d6141afc428688fa 329 Pfam PF01193 RNA polymerase Rpb3/Rpb11 dimerisation domain 26 224 1.5E-20 T 12-10-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 VAPA_1c52370 dd875480d921b8a3d6141afc428688fa 329 Pfam PF03118 Bacterial RNA polymerase, alpha chain C terminal domain 251 308 8.3E-25 T 12-10-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 VAPA_1c52370 dd875480d921b8a3d6141afc428688fa 329 Hamap MF_00059 DNA-directed RNA polymerase subunit alpha [rpoA]. 2 317 35.327 T 12-10-2018 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 VAPA_1c52370 dd875480d921b8a3d6141afc428688fa 329 Gene3D G3DSA:1.10.150.20 245 328 2.5E-37 T 12-10-2018 VAPA_1c52370 dd875480d921b8a3d6141afc428688fa 329 TIGRFAM TIGR02027 rpoA: DNA-directed RNA polymerase, alpha subunit 21 316 3.1E-107 T 12-10-2018 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 VAPA_1c52370 dd875480d921b8a3d6141afc428688fa 329 Gene3D G3DSA:2.170.120.12 50 173 9.2E-82 T 12-10-2018 IPR036643 DNA-directed RNA polymerase, insert domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 VAPA_1c52370 dd875480d921b8a3d6141afc428688fa 329 SUPERFAMILY SSF47789 251 323 8.5E-27 T 12-10-2018 VAPA_1c52370 dd875480d921b8a3d6141afc428688fa 329 SMART SM00662 20 230 1.4E-94 T 12-10-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 VAPA_1c52370 dd875480d921b8a3d6141afc428688fa 329 Gene3D G3DSA:3.30.1360.10 14 224 9.2E-82 T 12-10-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 VAPA_1c52370 dd875480d921b8a3d6141afc428688fa 329 SUPERFAMILY SSF56553 50 174 3.79E-42 T 12-10-2018 IPR036643 DNA-directed RNA polymerase, insert domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 VAPA_1c52370 dd875480d921b8a3d6141afc428688fa 329 ProDom PD001179 RNA POLYMERASE ALPHA DNA-DIRECTED SUBUNIT CHAIN NUCLEOTIDYLTRANSFERASE TRANSFERASE TRANSCRIPTION TRANSCRIPTASE 256 326 1.0E-34 T 12-10-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 VAPA_1c52370 dd875480d921b8a3d6141afc428688fa 329 SUPERFAMILY SSF55257 4 229 7.75E-30 T 12-10-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 VAPA_1c52370 dd875480d921b8a3d6141afc428688fa 329 Pfam PF01000 RNA polymerase Rpb3/RpoA insert domain 61 150 4.4E-25 T 12-10-2018 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 VAPA_1c10420 c60bed41d70f0bd4dd660967617a999c 419 SUPERFAMILY SSF81301 1 131 1.74E-26 T 12-10-2018 VAPA_1c10420 c60bed41d70f0bd4dd660967617a999c 419 SUPERFAMILY SSF81891 132 369 2.22E-53 T 12-10-2018 VAPA_1c10420 c60bed41d70f0bd4dd660967617a999c 419 Pfam PF01966 HD domain 241 338 4.0E-10 T 12-10-2018 IPR006674 HD domain VAPA_1c10420 c60bed41d70f0bd4dd660967617a999c 419 Pfam PF12627 Probable RNA and SrmB- binding site of polymerase A 159 221 1.9E-11 T 12-10-2018 IPR032828 tRNA nucleotidyltransferase/poly(A) polymerase, RNA and SrmB- binding domain Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 VAPA_1c10420 c60bed41d70f0bd4dd660967617a999c 419 Hamap MF_01261 Multifunctional CCA protein [cca]. 1 418 50.287 T 12-10-2018 IPR012006 tRNA nucleotidyltransferase, proteobacteria GO:0001680|GO:0003723|GO:0004810|GO:0005524 VAPA_1c10420 c60bed41d70f0bd4dd660967617a999c 419 Gene3D G3DSA:3.30.460.10 1 133 2.4E-25 T 12-10-2018 VAPA_1c10420 c60bed41d70f0bd4dd660967617a999c 419 Pfam PF01743 Poly A polymerase head domain 3 134 2.3E-16 T 12-10-2018 IPR002646 Poly A polymerase, head domain GO:0003723|GO:0006396|GO:0016779 Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 VAPA_1c10420 c60bed41d70f0bd4dd660967617a999c 419 Gene3D G3DSA:1.10.3090.10 134 417 4.6E-38 T 12-10-2018 VAPA_1c10420 c60bed41d70f0bd4dd660967617a999c 419 PIRSF PIRSF000813 1 418 1.0E-179 T 12-10-2018 IPR012006 tRNA nucleotidyltransferase, proteobacteria GO:0001680|GO:0003723|GO:0004810|GO:0005524 VAPA_2c01940 12f6dad8b1052714b4b95b38de8e3402 321 SUPERFAMILY SSF54292 213 320 1.31E-28 T 12-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 VAPA_2c01940 12f6dad8b1052714b4b95b38de8e3402 321 Gene3D G3DSA:3.10.20.30 226 321 1.6E-23 T 12-10-2018 IPR012675 Beta-grasp domain superfamily VAPA_2c01940 12f6dad8b1052714b4b95b38de8e3402 321 SUPERFAMILY SSF63380 4 100 1.89E-27 T 12-10-2018 IPR017938 Riboflavin synthase-like beta-barrel VAPA_2c01940 12f6dad8b1052714b4b95b38de8e3402 321 Gene3D G3DSA:3.40.50.80 102 223 1.6E-24 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain VAPA_2c01940 12f6dad8b1052714b4b95b38de8e3402 321 Gene3D G3DSA:2.40.30.10 2 101 1.9E-30 T 12-10-2018 VAPA_2c01940 12f6dad8b1052714b4b95b38de8e3402 321 PRINTS PR00409 Phthalate dioxygenase reductase family signature 112 131 3.8E-52 T 12-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 VAPA_2c01940 12f6dad8b1052714b4b95b38de8e3402 321 PRINTS PR00409 Phthalate dioxygenase reductase family signature 40 52 3.8E-52 T 12-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 VAPA_2c01940 12f6dad8b1052714b4b95b38de8e3402 321 PRINTS PR00409 Phthalate dioxygenase reductase family signature 137 146 3.8E-52 T 12-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 VAPA_2c01940 12f6dad8b1052714b4b95b38de8e3402 321 PRINTS PR00409 Phthalate dioxygenase reductase family signature 90 104 3.8E-52 T 12-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 VAPA_2c01940 12f6dad8b1052714b4b95b38de8e3402 321 PRINTS PR00409 Phthalate dioxygenase reductase family signature 76 90 3.8E-52 T 12-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 VAPA_2c01940 12f6dad8b1052714b4b95b38de8e3402 321 PRINTS PR00409 Phthalate dioxygenase reductase family signature 191 199 3.8E-52 T 12-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 VAPA_2c01940 12f6dad8b1052714b4b95b38de8e3402 321 PRINTS PR00409 Phthalate dioxygenase reductase family signature 30 40 3.8E-52 T 12-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 VAPA_2c01940 12f6dad8b1052714b4b95b38de8e3402 321 PRINTS PR00409 Phthalate dioxygenase reductase family signature 52 66 3.8E-52 T 12-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 VAPA_2c01940 12f6dad8b1052714b4b95b38de8e3402 321 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 242 311 8.9E-11 T 12-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 VAPA_2c01940 12f6dad8b1052714b4b95b38de8e3402 321 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 270 278 - T 12-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 VAPA_2c01940 12f6dad8b1052714b4b95b38de8e3402 321 SUPERFAMILY SSF52343 101 221 7.46E-28 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain VAPA_1c07080 9890ba4ae584939ae44cb088a8a0fe94 628 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 540 549 - T 12-10-2018 IPR025944 Sigma-54 interaction domain, conserved site VAPA_1c07080 9890ba4ae584939ae44cb088a8a0fe94 628 SUPERFAMILY SSF46689 586 624 7.47E-9 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 VAPA_1c07080 9890ba4ae584939ae44cb088a8a0fe94 628 SUPERFAMILY SSF55781 66 206 1.83E-7 T 12-10-2018 VAPA_1c07080 9890ba4ae584939ae44cb088a8a0fe94 628 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 351 364 - T 12-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 VAPA_1c07080 9890ba4ae584939ae44cb088a8a0fe94 628 Pfam PF00158 Sigma-54 interaction domain 327 493 3.8E-54 T 12-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 VAPA_1c07080 9890ba4ae584939ae44cb088a8a0fe94 628 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 605 625 8.3E-9 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 VAPA_1c07080 9890ba4ae584939ae44cb088a8a0fe94 628 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 588 605 8.3E-9 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 VAPA_1c07080 9890ba4ae584939ae44cb088a8a0fe94 628 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 414 429 - T 12-10-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 VAPA_1c07080 9890ba4ae584939ae44cb088a8a0fe94 628 Gene3D G3DSA:3.30.450.40 19 207 2.6E-33 T 12-10-2018 IPR029016 GAF-like domain superfamily VAPA_1c07080 9890ba4ae584939ae44cb088a8a0fe94 628 SMART SM00382 347 491 1.8E-9 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c07080 9890ba4ae584939ae44cb088a8a0fe94 628 Pfam PF02954 Bacterial regulatory protein, Fis family 587 620 2.4E-10 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 VAPA_1c07080 9890ba4ae584939ae44cb088a8a0fe94 628 Gene3D G3DSA:3.40.50.300 315 499 2.7E-54 T 12-10-2018 VAPA_1c07080 9890ba4ae584939ae44cb088a8a0fe94 628 Gene3D G3DSA:1.10.8.60 500 571 6.8E-13 T 12-10-2018 VAPA_1c07080 9890ba4ae584939ae44cb088a8a0fe94 628 Gene3D G3DSA:1.10.10.60 586 624 5.5E-12 T 12-10-2018 VAPA_1c07080 9890ba4ae584939ae44cb088a8a0fe94 628 SUPERFAMILY SSF52540 326 570 1.67E-52 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c08390 414d66a32d6d4ced0778b250aa87003f 217 Pfam PF00440 Bacterial regulatory proteins, tetR family 37 81 3.2E-12 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 VAPA_1c08390 414d66a32d6d4ced0778b250aa87003f 217 Gene3D G3DSA:1.10.357.10 32 217 1.7E-56 T 12-10-2018 VAPA_1c08390 414d66a32d6d4ced0778b250aa87003f 217 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 37 50 7.0E-6 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 VAPA_1c08390 414d66a32d6d4ced0778b250aa87003f 217 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 58 81 7.0E-6 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 VAPA_1c08390 414d66a32d6d4ced0778b250aa87003f 217 SUPERFAMILY SSF48498 106 212 2.36E-8 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily VAPA_1c08390 414d66a32d6d4ced0778b250aa87003f 217 SUPERFAMILY SSF46689 25 99 1.33E-13 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 VAPA_1c47460 0172bf87043790ca8ff6657d42301d66 254 Gene3D G3DSA:3.40.50.300 62 247 1.7E-38 T 12-10-2018 VAPA_1c47460 0172bf87043790ca8ff6657d42301d66 254 SUPERFAMILY SSF52540 68 228 1.06E-20 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c47460 0172bf87043790ca8ff6657d42301d66 254 SMART SM00382 98 231 2.0E-9 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c47460 0172bf87043790ca8ff6657d42301d66 254 PIRSF PIRSF003073 1 252 7.6E-73 T 12-10-2018 IPR028350 DNA replication protein DnaC/insertion sequence putative ATP-binding protein VAPA_1c47460 0172bf87043790ca8ff6657d42301d66 254 Pfam PF01695 IstB-like ATP binding protein 54 230 1.1E-38 T 12-10-2018 IPR002611 IstB-like ATP-binding protein GO:0005524 VAPA_1c22030 360f14bec2f679e3a0562cfe741a7b52 270 SUPERFAMILY SSF46689 161 211 1.79E-6 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 VAPA_1c22030 360f14bec2f679e3a0562cfe741a7b52 270 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 229 244 1.8E-5 T 12-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 VAPA_1c22030 360f14bec2f679e3a0562cfe741a7b52 270 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 244 260 1.8E-5 T 12-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 VAPA_1c22030 360f14bec2f679e3a0562cfe741a7b52 270 Pfam PF12833 Helix-turn-helix domain 185 259 1.7E-24 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 VAPA_1c22030 360f14bec2f679e3a0562cfe741a7b52 270 Gene3D G3DSA:1.10.10.60 222 269 1.4E-12 T 12-10-2018 VAPA_1c22030 360f14bec2f679e3a0562cfe741a7b52 270 Gene3D G3DSA:1.10.10.60 161 221 6.6E-14 T 12-10-2018 VAPA_1c22030 360f14bec2f679e3a0562cfe741a7b52 270 SUPERFAMILY SSF51215 26 148 2.22E-16 T 12-10-2018 IPR037923 Transcription regulator HTH-like VAPA_1c22030 360f14bec2f679e3a0562cfe741a7b52 270 SMART SM00342 178 260 1.9E-28 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 VAPA_1c22030 360f14bec2f679e3a0562cfe741a7b52 270 Gene3D G3DSA:2.60.120.10 13 142 5.8E-11 T 12-10-2018 IPR014710 RmlC-like jelly roll fold VAPA_1c22030 360f14bec2f679e3a0562cfe741a7b52 270 SUPERFAMILY SSF46689 215 260 1.39E-10 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 VAPA_1c22030 360f14bec2f679e3a0562cfe741a7b52 270 Pfam PF02311 AraC-like ligand binding domain 20 130 6.3E-16 T 12-10-2018 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 VAPA_1c30570 48525f632aef0c9a53a44daa6a6ded68 354 Hamap MF_00323 Ferrochelatase [hemH]. 18 338 36.677 T 12-10-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 VAPA_1c30570 48525f632aef0c9a53a44daa6a6ded68 354 Gene3D G3DSA:3.40.50.1400 181 319 2.2E-95 T 12-10-2018 VAPA_1c30570 48525f632aef0c9a53a44daa6a6ded68 354 TIGRFAM TIGR00109 hemH: ferrochelatase 18 332 9.1E-87 T 12-10-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 VAPA_1c30570 48525f632aef0c9a53a44daa6a6ded68 354 Gene3D G3DSA:3.40.50.1400 19 338 2.2E-95 T 12-10-2018 VAPA_1c30570 48525f632aef0c9a53a44daa6a6ded68 354 Pfam PF00762 Ferrochelatase 19 337 2.8E-110 T 12-10-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 VAPA_1c30570 48525f632aef0c9a53a44daa6a6ded68 354 ProSitePatterns PS00534 Ferrochelatase signature. 207 227 - T 12-10-2018 IPR019772 Ferrochelatase, active site GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 VAPA_1c30570 48525f632aef0c9a53a44daa6a6ded68 354 SUPERFAMILY SSF53800 18 343 2.78E-105 T 12-10-2018 VAPA_1c34280 86525cc2030a376c6564b741c27c37c1 336 PIRSF PIRSF006470 1 333 4.1E-113 T 12-10-2018 IPR004682 TRAP transporter solute receptor, DctP family GO:0030288|GO:0055085 VAPA_1c34280 86525cc2030a376c6564b741c27c37c1 336 SUPERFAMILY SSF53850 142 211 6.59E-5 T 12-10-2018 VAPA_1c34280 86525cc2030a376c6564b741c27c37c1 336 Gene3D G3DSA:3.40.190.170 26 336 7.9E-115 T 12-10-2018 IPR038404 TRAP transporter solute receptor DctP superfamily VAPA_1c34280 86525cc2030a376c6564b741c27c37c1 336 TIGRFAM TIGR00787 dctP: TRAP transporter solute receptor, DctP family 34 290 1.1E-79 T 12-10-2018 IPR004682 TRAP transporter solute receptor, DctP family GO:0030288|GO:0055085 VAPA_1c34280 86525cc2030a376c6564b741c27c37c1 336 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 41 314 1.3E-90 T 12-10-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0030288|GO:0055085 VAPA_1c01180 c6280bdede57093943d1689ccb13fa0e 346 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 34 264 1.5E-22 T 12-10-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0030288|GO:0055085 VAPA_1c01180 c6280bdede57093943d1689ccb13fa0e 346 Gene3D G3DSA:3.40.190.170 17 342 2.4E-60 T 12-10-2018 IPR038404 TRAP transporter solute receptor DctP superfamily VAPA_1c01180 c6280bdede57093943d1689ccb13fa0e 346 SUPERFAMILY SSF53850 138 271 1.57E-5 T 12-10-2018 VAPA_1c31800 72b0b1abdac7d9251be4676b0441290b 181 Hamap MF_00073 Transcription antitermination protein NusB [nusB]. 35 166 19.502 T 12-10-2018 IPR011605 NusB antitermination factor GO:0006353 VAPA_1c31800 72b0b1abdac7d9251be4676b0441290b 181 Gene3D G3DSA:1.10.940.10 31 170 6.5E-38 T 12-10-2018 IPR035926 NusB-like superfamily VAPA_1c31800 72b0b1abdac7d9251be4676b0441290b 181 TIGRFAM TIGR01951 nusB: transcription antitermination factor NusB 36 164 3.3E-33 T 12-10-2018 IPR011605 NusB antitermination factor GO:0006353 VAPA_1c31800 72b0b1abdac7d9251be4676b0441290b 181 SUPERFAMILY SSF48013 35 166 9.81E-38 T 12-10-2018 IPR035926 NusB-like superfamily VAPA_1c31800 72b0b1abdac7d9251be4676b0441290b 181 Pfam PF01029 NusB family 39 161 4.5E-30 T 12-10-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 VAPA_1c51180 58914ae8fa4af3399019d49ac3b7b9bc 626 Gene3D G3DSA:3.40.50.12780 28 344 4.4E-55 T 12-10-2018 VAPA_1c51180 58914ae8fa4af3399019d49ac3b7b9bc 626 Gene3D G3DSA:3.40.50.12780 354 489 2.1E-37 T 12-10-2018 VAPA_1c51180 58914ae8fa4af3399019d49ac3b7b9bc 626 ProSitePatterns PS00455 Putative AMP-binding domain signature. 210 221 - T 12-10-2018 IPR020845 AMP-binding, conserved site VAPA_1c51180 58914ae8fa4af3399019d49ac3b7b9bc 626 Gene3D G3DSA:3.30.300.30 490 620 3.5E-5 T 12-10-2018 VAPA_1c51180 58914ae8fa4af3399019d49ac3b7b9bc 626 Pfam PF00501 AMP-binding enzyme 36 496 3.5E-93 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 VAPA_1c51180 58914ae8fa4af3399019d49ac3b7b9bc 626 SUPERFAMILY SSF56801 11 625 1.09E-120 T 12-10-2018 VAPA_2c13290 855bbb3034245335938e6b8423dbd06f 835 Gene3D G3DSA:3.40.50.300 588 785 8.2E-21 T 12-10-2018 VAPA_2c13290 855bbb3034245335938e6b8423dbd06f 835 Pfam PF03135 CagE, TrbE, VirB family, component of type IV transporter system 187 396 1.6E-41 T 12-10-2018 IPR018145 CagE, TrbE, VirB component of type IV transporter system, central domain GO:0005524 VAPA_2c13290 855bbb3034245335938e6b8423dbd06f 835 SUPERFAMILY SSF52540 398 748 3.4E-31 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_2c13290 855bbb3034245335938e6b8423dbd06f 835 TIGRFAM TIGR00929 VirB4_CagE: type IV secretion/conjugal transfer ATPase, VirB4 family 13 818 4.5E-217 T 12-10-2018 IPR004346 CagE, TrbE, VirB component of type IV transporter system GO:0005524 VAPA_1c51160 17dc29d0a9e83fd728006d232fed4426 153 Pfam PF01878 EVE domain 3 151 2.1E-50 T 12-10-2018 IPR002740 EVE domain VAPA_1c51160 17dc29d0a9e83fd728006d232fed4426 153 SUPERFAMILY SSF88697 3 153 1.33E-56 T 12-10-2018 IPR015947 PUA-like superfamily VAPA_1c51160 17dc29d0a9e83fd728006d232fed4426 153 Gene3D G3DSA:3.10.590.10 1 153 9.5E-57 T 12-10-2018 VAPA_1c05530 8d64be05b24d1d5e1eef9b2ef27cf3b9 412 Gene3D G3DSA:3.40.50.150 175 398 4.8E-116 T 12-10-2018 VAPA_1c05530 8d64be05b24d1d5e1eef9b2ef27cf3b9 412 Pfam PF01170 Putative RNA methylase family UPF0020 168 322 8.7E-36 T 12-10-2018 IPR000241 Putative RNA methylase domain VAPA_1c05530 8d64be05b24d1d5e1eef9b2ef27cf3b9 412 SMART SM00981 61 160 3.6E-21 T 12-10-2018 IPR004114 THUMP domain GO:0003723 VAPA_1c05530 8d64be05b24d1d5e1eef9b2ef27cf3b9 412 Gene3D G3DSA:3.30.2130.30 7 263 4.8E-116 T 12-10-2018 VAPA_1c05530 8d64be05b24d1d5e1eef9b2ef27cf3b9 412 Pfam PF02926 THUMP domain 23 160 3.3E-12 T 12-10-2018 IPR004114 THUMP domain GO:0003723 VAPA_1c05530 8d64be05b24d1d5e1eef9b2ef27cf3b9 412 SUPERFAMILY SSF53335 147 401 8.74E-41 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase VAPA_1c48320 9fb01f98f00d3cdf16929c67ac4beb80 231 Hamap MF_02071 Endolytic peptidoglycan transglycosylase RlpA [rlpA]. 22 190 22.04 T 12-10-2018 IPR034718 Endolytic peptidoglycan transglycosylase RlpA GO:0016829 VAPA_1c48320 9fb01f98f00d3cdf16929c67ac4beb80 231 Gene3D G3DSA:2.40.40.10 97 191 2.8E-33 T 12-10-2018 IPR036908 RlpA-like domain superfamily VAPA_1c48320 9fb01f98f00d3cdf16929c67ac4beb80 231 SUPERFAMILY SSF50685 102 183 1.36E-8 T 12-10-2018 IPR036908 RlpA-like domain superfamily VAPA_1c48320 9fb01f98f00d3cdf16929c67ac4beb80 231 Pfam PF03330 Lytic transglycolase 99 185 3.1E-24 T 12-10-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain VAPA_1c48320 9fb01f98f00d3cdf16929c67ac4beb80 231 TIGRFAM TIGR00413 rlpA: rare lipoprotein A 101 194 1.9E-41 T 12-10-2018 IPR012997 Rare lipoprotein A VAPA_1c27380 b3a58673a6c4b2841a73b52d6403cabf 147 Pfam PF00582 Universal stress protein family 1 147 5.8E-33 T 12-10-2018 IPR006016 UspA VAPA_1c27380 b3a58673a6c4b2841a73b52d6403cabf 147 PRINTS PR01438 Universal stress protein signature 107 119 3.5E-18 T 12-10-2018 IPR006015 Universal stress protein A VAPA_1c27380 b3a58673a6c4b2841a73b52d6403cabf 147 PRINTS PR01438 Universal stress protein signature 125 147 3.5E-18 T 12-10-2018 IPR006015 Universal stress protein A VAPA_1c27380 b3a58673a6c4b2841a73b52d6403cabf 147 PRINTS PR01438 Universal stress protein signature 2 20 3.5E-18 T 12-10-2018 IPR006015 Universal stress protein A VAPA_1c27380 b3a58673a6c4b2841a73b52d6403cabf 147 PIRSF PIRSF006276 1 147 4.8E-18 T 12-10-2018 IPR006015 Universal stress protein A VAPA_1c27380 b3a58673a6c4b2841a73b52d6403cabf 147 Gene3D G3DSA:3.40.50.620 1 147 2.0E-39 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold VAPA_1c27380 b3a58673a6c4b2841a73b52d6403cabf 147 SUPERFAMILY SSF52402 2 147 6.95E-38 T 12-10-2018 VAPA_1c35650 ec553c1ed61e61d4c0fbb624dfdc7396 303 TIGRFAM TIGR02225 recomb_XerD: tyrosine recombinase XerD 14 302 3.9E-108 T 12-10-2018 IPR011932 Tyrosine recombinase XerD GO:0006310|GO:0009009 VAPA_1c35650 ec553c1ed61e61d4c0fbb624dfdc7396 303 Gene3D G3DSA:1.10.443.10 116 297 3.4E-67 T 12-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 VAPA_1c35650 ec553c1ed61e61d4c0fbb624dfdc7396 303 Pfam PF00589 Phage integrase family 118 288 1.1E-46 T 12-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 VAPA_1c35650 ec553c1ed61e61d4c0fbb624dfdc7396 303 SUPERFAMILY SSF47823 10 106 5.89E-31 T 12-10-2018 VAPA_1c35650 ec553c1ed61e61d4c0fbb624dfdc7396 303 SUPERFAMILY SSF56349 114 301 1.53E-55 T 12-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 VAPA_1c35650 ec553c1ed61e61d4c0fbb624dfdc7396 303 Gene3D G3DSA:1.10.150.130 8 104 5.4E-20 T 12-10-2018 IPR010998 Integrase/recombinase, N-terminal VAPA_1c35650 ec553c1ed61e61d4c0fbb624dfdc7396 303 Hamap MF_01808 Tyrosine recombinase XerC [xerC]. 10 303 53.624 T 12-10-2018 IPR023009 Tyrosine recombinase XerC/XerD VAPA_1c35650 ec553c1ed61e61d4c0fbb624dfdc7396 303 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 12 95 2.7E-18 T 12-10-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 VAPA_1c35650 ec553c1ed61e61d4c0fbb624dfdc7396 303 Hamap MF_01807 Tyrosine recombinase XerD [xerD]. 8 303 56.442 T 12-10-2018 IPR011932 Tyrosine recombinase XerD GO:0006310|GO:0009009 VAPA_1c26170 6321f5de5f8604f8c202d5641b4feac9 136 TIGRFAM TIGR00357 TIGR00357: methionine-R-sulfoxide reductase 7 134 9.6E-51 T 12-10-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 VAPA_1c26170 6321f5de5f8604f8c202d5641b4feac9 136 Hamap MF_01400 Peptide methionine sulfoxide reductase MsrB [msrB]. 8 136 34.709 T 12-10-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 VAPA_1c26170 6321f5de5f8604f8c202d5641b4feac9 136 Pfam PF01641 SelR domain 22 134 8.6E-49 T 12-10-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 VAPA_1c26170 6321f5de5f8604f8c202d5641b4feac9 136 Gene3D G3DSA:2.170.150.20 1 136 4.7E-56 T 12-10-2018 VAPA_1c26170 6321f5de5f8604f8c202d5641b4feac9 136 SUPERFAMILY SSF51316 6 135 1.46E-53 T 12-10-2018 IPR011057 Mss4-like superfamily VAPA_1c54680 3d521b7b61aa370c9e3bf934d2d3afc1 333 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 150 157 - T 12-10-2018 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 VAPA_1c54680 3d521b7b61aa370c9e3bf934d2d3afc1 333 Gene3D G3DSA:3.30.360.10 151 316 4.1E-150 T 12-10-2018 VAPA_1c54680 3d521b7b61aa370c9e3bf934d2d3afc1 333 Gene3D G3DSA:3.40.50.720 4 327 4.1E-150 T 12-10-2018 VAPA_1c54680 3d521b7b61aa370c9e3bf934d2d3afc1 333 SUPERFAMILY SSF51735 3 168 1.51E-68 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c54680 3d521b7b61aa370c9e3bf934d2d3afc1 333 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 3 104 6.2E-40 T 12-10-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 VAPA_1c54680 3d521b7b61aa370c9e3bf934d2d3afc1 333 TIGRFAM TIGR01534 GAPDH-I: glyceraldehyde-3-phosphate dehydrogenase, type I 4 325 4.2E-135 T 12-10-2018 IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I GO:0006006|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.12|KEGG: 00710+1.2.1.12|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 VAPA_1c54680 3d521b7b61aa370c9e3bf934d2d3afc1 333 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 146 164 6.3E-47 T 12-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 VAPA_1c54680 3d521b7b61aa370c9e3bf934d2d3afc1 333 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 270 285 6.3E-47 T 12-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 VAPA_1c54680 3d521b7b61aa370c9e3bf934d2d3afc1 333 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 230 247 6.3E-47 T 12-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 VAPA_1c54680 3d521b7b61aa370c9e3bf934d2d3afc1 333 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 111 124 6.3E-47 T 12-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 VAPA_1c54680 3d521b7b61aa370c9e3bf934d2d3afc1 333 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 173 189 6.3E-47 T 12-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 VAPA_1c54680 3d521b7b61aa370c9e3bf934d2d3afc1 333 SUPERFAMILY SSF55347 151 314 1.25E-73 T 12-10-2018 VAPA_1c54680 3d521b7b61aa370c9e3bf934d2d3afc1 333 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 157 314 3.8E-66 T 12-10-2018 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 VAPA_1c54680 3d521b7b61aa370c9e3bf934d2d3afc1 333 SMART SM00846 3 152 2.8E-99 T 12-10-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 VAPA_1c54680 3d521b7b61aa370c9e3bf934d2d3afc1 333 PIRSF PIRSF000149 1 333 6.6E-131 T 12-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 VAPA_1c14090 af1d69693c08fee4a20fda653a111b3f 140 SUPERFAMILY SSF54427 1 139 7.53E-73 T 12-10-2018 IPR032710 NTF2-like domain superfamily VAPA_1c14090 af1d69693c08fee4a20fda653a111b3f 140 Pfam PF07080 Protein of unknown function (DUF1348) 8 137 2.5E-66 T 12-10-2018 IPR009783 Protein of unknown function DUF1348 VAPA_1c14090 af1d69693c08fee4a20fda653a111b3f 140 Gene3D G3DSA:3.10.450.50 11 140 6.7E-66 T 12-10-2018 VAPA_1c36760 3f8c2d129d95c7938f9c9e47bcb7332a 443 SMART SM00388 223 289 3.0E-16 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 VAPA_1c36760 3f8c2d129d95c7938f9c9e47bcb7332a 443 TIGRFAM TIGR01386 cztS_silS_copS: heavy metal sensor kinase 7 440 7.1E-109 T 12-10-2018 IPR006290 Heavy metal sensor kinase GO:0000160|GO:0004673|GO:0016020 VAPA_1c36760 3f8c2d129d95c7938f9c9e47bcb7332a 443 Pfam PF00512 His Kinase A (phospho-acceptor) domain 224 289 3.3E-14 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 VAPA_1c36760 3f8c2d129d95c7938f9c9e47bcb7332a 443 SMART SM00387 332 443 3.9E-28 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase VAPA_1c36760 3f8c2d129d95c7938f9c9e47bcb7332a 443 SUPERFAMILY SSF55874 279 441 7.33E-28 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_1c36760 3f8c2d129d95c7938f9c9e47bcb7332a 443 Gene3D G3DSA:3.30.565.10 296 443 5.5E-25 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_1c36760 3f8c2d129d95c7938f9c9e47bcb7332a 443 Gene3D G3DSA:1.10.287.130 173 289 9.0E-17 T 12-10-2018 VAPA_1c36760 3f8c2d129d95c7938f9c9e47bcb7332a 443 PRINTS PR00344 Bacterial sensor protein C-terminal signature 369 383 1.1E-5 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c36760 3f8c2d129d95c7938f9c9e47bcb7332a 443 PRINTS PR00344 Bacterial sensor protein C-terminal signature 387 397 1.1E-5 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c36760 3f8c2d129d95c7938f9c9e47bcb7332a 443 PRINTS PR00344 Bacterial sensor protein C-terminal signature 404 422 1.1E-5 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c36760 3f8c2d129d95c7938f9c9e47bcb7332a 443 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 334 441 3.7E-16 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase VAPA_1c36760 3f8c2d129d95c7938f9c9e47bcb7332a 443 SUPERFAMILY SSF47384 207 289 1.41E-15 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 VAPA_1c52390 5f5af780069984dc2437c3dbda576c68 134 PIRSF PIRSF002131 2 134 2.8E-52 T 12-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 VAPA_1c52390 5f5af780069984dc2437c3dbda576c68 134 Gene3D G3DSA:3.30.420.80 6 134 4.3E-53 T 12-10-2018 IPR036967 Ribosomal protein S11 superfamily GO:0003735|GO:0005840|GO:0006412 VAPA_1c52390 5f5af780069984dc2437c3dbda576c68 134 SUPERFAMILY SSF53137 19 134 1.7E-45 T 12-10-2018 VAPA_1c52390 5f5af780069984dc2437c3dbda576c68 134 Hamap MF_01310 30S ribosomal protein S11 [rpsK]. 3 134 31.948 T 12-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 VAPA_1c52390 5f5af780069984dc2437c3dbda576c68 134 ProSitePatterns PS00054 Ribosomal protein S11 signature. 102 124 - T 12-10-2018 IPR018102 Ribosomal S11, conserved site VAPA_1c52390 5f5af780069984dc2437c3dbda576c68 134 TIGRFAM TIGR03632 uS11_bact: ribosomal protein uS11 15 131 2.6E-54 T 12-10-2018 IPR019981 Ribosomal protein S11, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 VAPA_1c52390 5f5af780069984dc2437c3dbda576c68 134 Pfam PF00411 Ribosomal protein S11 24 133 3.5E-49 T 12-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 VAPA_1c49080 4e5f0672b0d8221f60849b4073877869 407 SUPERFAMILY SSF103473 23 402 2.22E-47 T 12-10-2018 IPR036259 MFS transporter superfamily VAPA_1c49080 4e5f0672b0d8221f60849b4073877869 407 Gene3D G3DSA:1.20.1250.20 22 401 1.7E-41 T 12-10-2018 VAPA_1c49080 4e5f0672b0d8221f60849b4073877869 407 Pfam PF07690 Major Facilitator Superfamily 30 333 4.5E-27 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 VAPA_1c00970 baf67044d7fad2912d36286eb25ffbbc 432 PIRSF PIRSF501177 1 432 2.1E-228 T 12-10-2018 IPR017634 Benzoyl-CoA oxygenase/reductase, BoxA protein KEGG: 00362+1.14.13.208|MetaCyc: PWY-1361 VAPA_1c00970 baf67044d7fad2912d36286eb25ffbbc 432 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 320 329 3.0E-18 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 VAPA_1c00970 baf67044d7fad2912d36286eb25ffbbc 432 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 290 309 3.0E-18 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 VAPA_1c00970 baf67044d7fad2912d36286eb25ffbbc 432 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 254 263 3.0E-18 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 VAPA_1c00970 baf67044d7fad2912d36286eb25ffbbc 432 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 195 205 3.0E-18 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 VAPA_1c00970 baf67044d7fad2912d36286eb25ffbbc 432 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 362 378 3.0E-18 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 VAPA_1c00970 baf67044d7fad2912d36286eb25ffbbc 432 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 386 394 3.0E-18 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 VAPA_1c00970 baf67044d7fad2912d36286eb25ffbbc 432 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 218 225 3.0E-18 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 VAPA_1c00970 baf67044d7fad2912d36286eb25ffbbc 432 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 20 31 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site VAPA_1c00970 baf67044d7fad2912d36286eb25ffbbc 432 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 49 60 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site VAPA_1c00970 baf67044d7fad2912d36286eb25ffbbc 432 Gene3D G3DSA:3.40.50.80 276 432 7.5E-36 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain VAPA_1c00970 baf67044d7fad2912d36286eb25ffbbc 432 Gene3D G3DSA:3.30.70.20 13 65 2.7E-12 T 12-10-2018 VAPA_1c00970 baf67044d7fad2912d36286eb25ffbbc 432 Pfam PF00175 Oxidoreductase NAD-binding domain 291 399 2.2E-13 T 12-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 VAPA_1c00970 baf67044d7fad2912d36286eb25ffbbc 432 SUPERFAMILY SSF63380 142 283 7.85E-36 T 12-10-2018 IPR017938 Riboflavin synthase-like beta-barrel VAPA_1c00970 baf67044d7fad2912d36286eb25ffbbc 432 PIRSF PIRSF000361 61 432 1.1E-69 T 12-10-2018 IPR015701 Ferredoxin--NADP reductase GO:0016491|GO:0055114 KEGG: 00195+1.18.1.2|MetaCyc: PWY-101 VAPA_1c00970 baf67044d7fad2912d36286eb25ffbbc 432 TIGRFAM TIGR03224 benzo_boxA: benzoyl-CoA oxygenase/reductase, BoxA protein 9 432 5.1E-225 T 12-10-2018 IPR017634 Benzoyl-CoA oxygenase/reductase, BoxA protein KEGG: 00362+1.14.13.208|MetaCyc: PWY-1361 VAPA_1c00970 baf67044d7fad2912d36286eb25ffbbc 432 SUPERFAMILY SSF52343 278 432 9.43E-35 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain VAPA_1c00970 baf67044d7fad2912d36286eb25ffbbc 432 SUPERFAMILY SSF54862 14 74 3.91E-19 T 12-10-2018 VAPA_1c00970 baf67044d7fad2912d36286eb25ffbbc 432 Pfam PF00970 Oxidoreductase FAD-binding domain 212 277 9.8E-5 T 12-10-2018 IPR008333 Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain Reactome: R-HSA-1237044 VAPA_1c00970 baf67044d7fad2912d36286eb25ffbbc 432 Gene3D G3DSA:2.40.30.10 134 275 5.0E-38 T 12-10-2018 VAPA_1c00970 baf67044d7fad2912d36286eb25ffbbc 432 Pfam PF00037 4Fe-4S binding domain 15 36 5.4E-7 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain VAPA_2c00940 c26e180dafb1b9d24e18e440c466f72a 316 Hamap MF_00224 Dihydroorotate dehydrogenase [pyrD]. 4 298 35.459 T 12-10-2018 IPR024920 Dihydroorotate dehydrogenase, class 1 GO:0004152|GO:0005737|GO:0006221 VAPA_2c00940 c26e180dafb1b9d24e18e440c466f72a 316 TIGRFAM TIGR01037 pyrD_sub1_fam: dihydroorotate dehydrogenase family protein 4 297 1.7E-97 T 12-10-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 VAPA_2c00940 c26e180dafb1b9d24e18e440c466f72a 316 ProSitePatterns PS00912 Dihydroorotate dehydrogenase signature 2. 236 256 - T 12-10-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 VAPA_2c00940 c26e180dafb1b9d24e18e440c466f72a 316 Pfam PF01180 Dihydroorotate dehydrogenase 4 281 5.3E-68 T 12-10-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 VAPA_2c00940 c26e180dafb1b9d24e18e440c466f72a 316 Gene3D G3DSA:2.30.26.10 53 213 9.3E-90 T 12-10-2018 IPR023359 Dihydroorotate dehydrogenase A, chain A, domain 2 VAPA_2c00940 c26e180dafb1b9d24e18e440c466f72a 316 ProSitePatterns PS00911 Dihydroorotate dehydrogenase signature 1. 38 57 - T 12-10-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 VAPA_2c00940 c26e180dafb1b9d24e18e440c466f72a 316 PIRSF PIRSF000164 1 299 3.0E-73 T 12-10-2018 IPR012135 Dihydroorotate dehydrogenase, class 1/ 2 GO:0004152|GO:0006222|GO:0055114 VAPA_2c00940 c26e180dafb1b9d24e18e440c466f72a 316 SUPERFAMILY SSF51395 2 297 4.03E-79 T 12-10-2018 VAPA_2c00940 c26e180dafb1b9d24e18e440c466f72a 316 Gene3D G3DSA:3.20.20.70 13 289 9.3E-90 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 VAPA_1c42380 9f8b8a0354b71ab8fb48b9cef496d49a 323 SUPERFAMILY SSF53850 112 286 2.33E-12 T 12-10-2018 VAPA_1c42380 9f8b8a0354b71ab8fb48b9cef496d49a 323 PIRSF PIRSF017082 1 322 1.9E-74 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c42380 9f8b8a0354b71ab8fb48b9cef496d49a 323 Gene3D G3DSA:3.40.190.10 124 247 6.4E-104 T 12-10-2018 VAPA_1c42380 9f8b8a0354b71ab8fb48b9cef496d49a 323 Gene3D G3DSA:3.40.190.150 26 310 6.4E-104 T 12-10-2018 VAPA_1c42380 9f8b8a0354b71ab8fb48b9cef496d49a 323 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 45 314 8.0E-76 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c20460 ddd77dd9f2f32268ae21e7a24fc371b1 696 Pfam PF13549 ATP-grasp domain 478 695 1.2E-50 T 12-10-2018 VAPA_1c20460 ddd77dd9f2f32268ae21e7a24fc371b1 696 Gene3D G3DSA:3.40.50.720 5 132 1.2E-35 T 12-10-2018 VAPA_1c20460 ddd77dd9f2f32268ae21e7a24fc371b1 696 SMART SM00881 10 105 6.4E-28 T 12-10-2018 IPR003781 CoA-binding GO:0048037 VAPA_1c20460 ddd77dd9f2f32268ae21e7a24fc371b1 696 SUPERFAMILY SSF52210 303 459 9.29E-24 T 12-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 VAPA_1c20460 ddd77dd9f2f32268ae21e7a24fc371b1 696 SUPERFAMILY SSF51735 5 139 6.57E-30 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c20460 ddd77dd9f2f32268ae21e7a24fc371b1 696 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 159 293 9.9E-50 T 12-10-2018 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain VAPA_1c20460 ddd77dd9f2f32268ae21e7a24fc371b1 696 Gene3D G3DSA:3.30.470.20 479 691 1.1E-60 T 12-10-2018 VAPA_1c20460 ddd77dd9f2f32268ae21e7a24fc371b1 696 Gene3D G3DSA:3.40.50.261 135 298 1.2E-50 T 12-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 VAPA_1c20460 ddd77dd9f2f32268ae21e7a24fc371b1 696 Gene3D G3DSA:3.30.1490.20 498 573 1.1E-60 T 12-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 VAPA_1c20460 ddd77dd9f2f32268ae21e7a24fc371b1 696 SUPERFAMILY SSF56059 480 695 1.68E-35 T 12-10-2018 VAPA_1c20460 ddd77dd9f2f32268ae21e7a24fc371b1 696 SUPERFAMILY SSF52210 154 297 5.89E-40 T 12-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 VAPA_1c20460 ddd77dd9f2f32268ae21e7a24fc371b1 696 Pfam PF13380 CoA binding domain 14 136 1.9E-17 T 12-10-2018 IPR003781 CoA-binding GO:0048037 VAPA_1c20460 ddd77dd9f2f32268ae21e7a24fc371b1 696 Gene3D G3DSA:3.40.50.261 302 466 1.9E-26 T 12-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 VAPA_1c39440 d144becf5351859106cbe20ab8c94010 506 Gene3D G3DSA:3.30.300.30 406 504 9.4E-28 T 12-10-2018 VAPA_1c39440 d144becf5351859106cbe20ab8c94010 506 SUPERFAMILY SSF56801 5 505 1.23E-145 T 12-10-2018 VAPA_1c39440 d144becf5351859106cbe20ab8c94010 506 Pfam PF00501 AMP-binding enzyme 13 409 1.2E-96 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 VAPA_1c39440 d144becf5351859106cbe20ab8c94010 506 ProSitePatterns PS00455 Putative AMP-binding domain signature. 164 175 - T 12-10-2018 IPR020845 AMP-binding, conserved site VAPA_1c39440 d144becf5351859106cbe20ab8c94010 506 Gene3D G3DSA:3.40.50.12780 2 405 4.8E-109 T 12-10-2018 VAPA_1c39440 d144becf5351859106cbe20ab8c94010 506 Pfam PF13193 AMP-binding enzyme C-terminal domain 419 494 2.6E-17 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain VAPA_1c42940 6eddb8917bb9323d94499d68c26a760e 814 SUPERFAMILY SSF50182 627 692 2.62E-15 T 12-10-2018 IPR010920 LSM domain superfamily VAPA_1c42940 6eddb8917bb9323d94499d68c26a760e 814 SUPERFAMILY SSF82689 698 783 4.32E-9 T 12-10-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 VAPA_1c42940 6eddb8917bb9323d94499d68c26a760e 814 Pfam PF12607 Protein of unknown function (DUF3772) 138 198 1.6E-13 T 12-10-2018 IPR022249 Domain of unknown function DUF3772 VAPA_1c42940 6eddb8917bb9323d94499d68c26a760e 814 Gene3D G3DSA:3.30.70.100 695 786 8.6E-7 T 12-10-2018 VAPA_1c42940 6eddb8917bb9323d94499d68c26a760e 814 Gene3D G3DSA:2.30.30.60 642 691 7.8E-11 T 12-10-2018 IPR023408 Mechanosensitive ion channel MscS domain superfamily VAPA_1c42940 6eddb8917bb9323d94499d68c26a760e 814 SUPERFAMILY SSF82861 543 625 4.18E-11 T 12-10-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 VAPA_1c42940 6eddb8917bb9323d94499d68c26a760e 814 Pfam PF00924 Mechanosensitive ion channel 586 781 8.6E-38 T 12-10-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 VAPA_1c08100 baa5ac34b999c31fcda652f3d39e8711 471 SUPERFAMILY SSF53383 133 456 2.34E-69 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase VAPA_1c08100 baa5ac34b999c31fcda652f3d39e8711 471 Gene3D G3DSA:1.10.10.10 1 74 2.1E-19 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c08100 baa5ac34b999c31fcda652f3d39e8711 471 SMART SM00345 14 73 1.6E-16 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_1c08100 baa5ac34b999c31fcda652f3d39e8711 471 Pfam PF00392 Bacterial regulatory proteins, gntR family 11 73 3.4E-14 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_1c08100 baa5ac34b999c31fcda652f3d39e8711 471 Pfam PF00155 Aminotransferase class I and II 136 457 2.8E-28 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 VAPA_1c08100 baa5ac34b999c31fcda652f3d39e8711 471 Gene3D G3DSA:3.40.640.10 154 370 2.1E-70 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 VAPA_1c08100 baa5ac34b999c31fcda652f3d39e8711 471 SUPERFAMILY SSF46785 1 77 9.62E-21 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c08100 baa5ac34b999c31fcda652f3d39e8711 471 Gene3D G3DSA:3.90.1150.10 120 457 2.1E-70 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 VAPA_1c39900 a264b6ad7a3874ad05618f595e565404 410 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 31 98 1.0E-4 T 12-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 VAPA_1c39900 a264b6ad7a3874ad05618f595e565404 410 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 138 228 2.8E-12 T 12-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 VAPA_1c39900 a264b6ad7a3874ad05618f595e565404 410 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 286 386 1.6E-13 T 12-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 VAPA_1c39900 a264b6ad7a3874ad05618f595e565404 410 Gene3D G3DSA:1.10.540.10 17 123 4.2E-20 T 12-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 VAPA_1c39900 a264b6ad7a3874ad05618f595e565404 410 PIRSF PIRSF016578 6 121 7.0E-7 T 12-10-2018 VAPA_1c39900 a264b6ad7a3874ad05618f595e565404 410 PIRSF PIRSF016578 145 408 7.0E-23 T 12-10-2018 VAPA_1c39900 a264b6ad7a3874ad05618f595e565404 410 Gene3D G3DSA:2.40.110.10 150 240 4.0E-22 T 12-10-2018 VAPA_1c39900 a264b6ad7a3874ad05618f595e565404 410 SUPERFAMILY SSF56645 29 236 9.82E-41 T 12-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 VAPA_1c39900 a264b6ad7a3874ad05618f595e565404 410 Gene3D G3DSA:1.20.140.10 255 402 1.3E-25 T 12-10-2018 VAPA_1c39900 a264b6ad7a3874ad05618f595e565404 410 SUPERFAMILY SSF47203 264 403 3.38E-24 T 12-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 VAPA_1c03340 8aebf5205314d3c82dd751bbb388b2b5 531 ProSitePatterns PS00211 ABC transporters family signature. 155 169 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_1c03340 8aebf5205314d3c82dd751bbb388b2b5 531 SMART SM00382 44 232 2.5E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c03340 8aebf5205314d3c82dd751bbb388b2b5 531 Pfam PF00005 ABC transporter 296 448 5.8E-11 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c03340 8aebf5205314d3c82dd751bbb388b2b5 531 SUPERFAMILY SSF52540 19 241 6.55E-52 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c03340 8aebf5205314d3c82dd751bbb388b2b5 531 Gene3D G3DSA:3.40.50.300 20 269 5.4E-52 T 12-10-2018 VAPA_1c03340 8aebf5205314d3c82dd751bbb388b2b5 531 Gene3D G3DSA:3.40.50.300 278 518 1.4E-35 T 12-10-2018 VAPA_1c03340 8aebf5205314d3c82dd751bbb388b2b5 531 SUPERFAMILY SSF52540 280 508 1.12E-37 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c03340 8aebf5205314d3c82dd751bbb388b2b5 531 Pfam PF00005 ABC transporter 36 183 1.4E-28 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c30080 616fb8e5dfca6d33584884fd4926defc 273 Pfam PF01925 Sulfite exporter TauE/SafE 13 266 2.5E-52 T 12-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 VAPA_2c01950 ffbca30542b8325f196a133be8af4a2d 351 Gene3D G3DSA:2.102.10.10 2 130 3.6E-33 T 12-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 VAPA_2c01950 ffbca30542b8325f196a133be8af4a2d 351 Gene3D G3DSA:3.30.530.90 131 346 4.1E-67 T 12-10-2018 VAPA_2c01950 ffbca30542b8325f196a133be8af4a2d 351 Pfam PF00355 Rieske [2Fe-2S] domain 6 86 7.8E-17 T 12-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 VAPA_2c01950 ffbca30542b8325f196a133be8af4a2d 351 ProSitePatterns PS00570 Bacterial ring hydroxylating dioxygenases alpha-subunit signature. 47 69 - T 12-10-2018 IPR015881 Aromatic-ring-hydroxylating dioxygenase, 2Fe-2S-binding site GO:0005506|GO:0051537|GO:0055114 VAPA_2c01950 ffbca30542b8325f196a133be8af4a2d 351 SUPERFAMILY SSF50022 3 117 1.2E-30 T 12-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 VAPA_2c01950 ffbca30542b8325f196a133be8af4a2d 351 SUPERFAMILY SSF55961 116 342 5.77E-55 T 12-10-2018 VAPA_1c24150 94df72a4b69635549519af698dc13e70 380 Gene3D G3DSA:3.20.20.10 30 255 8.1E-115 T 12-10-2018 IPR029066 PLP-binding barrel VAPA_1c24150 94df72a4b69635549519af698dc13e70 380 SMART SM01119 276 364 1.5E-28 T 12-10-2018 IPR026956 D-serine dehydratase-like domain VAPA_1c24150 94df72a4b69635549519af698dc13e70 380 SUPERFAMILY SSF51419 28 263 5.89E-37 T 12-10-2018 IPR029066 PLP-binding barrel VAPA_1c24150 94df72a4b69635549519af698dc13e70 380 Pfam PF01168 Alanine racemase, N-terminal domain 28 257 1.0E-23 T 12-10-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 VAPA_1c24150 94df72a4b69635549519af698dc13e70 380 Gene3D G3DSA:2.40.37.20 21 377 8.1E-115 T 12-10-2018 VAPA_1c24150 94df72a4b69635549519af698dc13e70 380 Pfam PF14031 Putative serine dehydratase domain 276 363 1.3E-18 T 12-10-2018 IPR026956 D-serine dehydratase-like domain VAPA_1c24680 2e133d2ad52e0bd43fe0a31863514530 292 Gene3D G3DSA:3.40.50.150 43 279 8.3E-37 T 12-10-2018 VAPA_1c24680 2e133d2ad52e0bd43fe0a31863514530 292 SUPERFAMILY SSF53335 22 249 1.09E-36 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase VAPA_1c24680 2e133d2ad52e0bd43fe0a31863514530 292 Pfam PF01209 ubiE/COQ5 methyltransferase family 57 172 1.2E-16 T 12-10-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 VAPA_1c14530 114a09b5a1cc9d75fa47c14fec9b57dd 465 ProSitePatterns PS00163 Fumarate lyases signature. 284 293 - T 12-10-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 VAPA_1c14530 114a09b5a1cc9d75fa47c14fec9b57dd 465 PRINTS PR00145 Argininosuccinate lyase family signature 319 338 7.2E-68 T 12-10-2018 VAPA_1c14530 114a09b5a1cc9d75fa47c14fec9b57dd 465 PRINTS PR00145 Argininosuccinate lyase family signature 284 300 7.2E-68 T 12-10-2018 VAPA_1c14530 114a09b5a1cc9d75fa47c14fec9b57dd 465 PRINTS PR00145 Argininosuccinate lyase family signature 151 171 7.2E-68 T 12-10-2018 VAPA_1c14530 114a09b5a1cc9d75fa47c14fec9b57dd 465 PRINTS PR00145 Argininosuccinate lyase family signature 240 264 7.2E-68 T 12-10-2018 VAPA_1c14530 114a09b5a1cc9d75fa47c14fec9b57dd 465 PRINTS PR00145 Argininosuccinate lyase family signature 202 218 7.2E-68 T 12-10-2018 VAPA_1c14530 114a09b5a1cc9d75fa47c14fec9b57dd 465 PRINTS PR00145 Argininosuccinate lyase family signature 110 132 7.2E-68 T 12-10-2018 VAPA_1c14530 114a09b5a1cc9d75fa47c14fec9b57dd 465 Hamap MF_00006 Argininosuccinate lyase [argH]. 11 462 42.606 T 12-10-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 VAPA_1c14530 114a09b5a1cc9d75fa47c14fec9b57dd 465 Gene3D G3DSA:1.10.275.10 34 238 1.8E-190 T 12-10-2018 IPR024083 Fumarase/histidase, N-terminal VAPA_1c14530 114a09b5a1cc9d75fa47c14fec9b57dd 465 Pfam PF14698 Argininosuccinate lyase C-terminal 372 439 6.1E-24 T 12-10-2018 IPR029419 Argininosuccinate lyase, C-terminal KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 VAPA_1c14530 114a09b5a1cc9d75fa47c14fec9b57dd 465 TIGRFAM TIGR00838 argH: argininosuccinate lyase 13 464 8.3E-186 T 12-10-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 VAPA_1c14530 114a09b5a1cc9d75fa47c14fec9b57dd 465 Pfam PF00206 Lyase 17 309 4.2E-75 T 12-10-2018 IPR022761 Fumarate lyase, N-terminal VAPA_1c14530 114a09b5a1cc9d75fa47c14fec9b57dd 465 SUPERFAMILY SSF48557 13 464 1.73E-149 T 12-10-2018 IPR008948 L-Aspartase-like GO:0003824 VAPA_1c14530 114a09b5a1cc9d75fa47c14fec9b57dd 465 PRINTS PR00149 Fumarate lyase superfamily signature 240 267 5.9E-29 T 12-10-2018 IPR000362 Fumarate lyase family VAPA_1c14530 114a09b5a1cc9d75fa47c14fec9b57dd 465 PRINTS PR00149 Fumarate lyase superfamily signature 284 300 5.9E-29 T 12-10-2018 IPR000362 Fumarate lyase family VAPA_1c14530 114a09b5a1cc9d75fa47c14fec9b57dd 465 PRINTS PR00149 Fumarate lyase superfamily signature 111 129 5.9E-29 T 12-10-2018 IPR000362 Fumarate lyase family VAPA_1c14530 114a09b5a1cc9d75fa47c14fec9b57dd 465 PRINTS PR00149 Fumarate lyase superfamily signature 156 174 5.9E-29 T 12-10-2018 IPR000362 Fumarate lyase family VAPA_1c14530 114a09b5a1cc9d75fa47c14fec9b57dd 465 Gene3D G3DSA:1.20.200.10 128 457 1.8E-190 T 12-10-2018 VAPA_1c14530 114a09b5a1cc9d75fa47c14fec9b57dd 465 Gene3D G3DSA:1.10.40.30 370 441 1.8E-190 T 12-10-2018 VAPA_2c07030 9cd17356bb4c4de9d812a95b78347c57 399 Gene3D G3DSA:3.40.50.2300 152 282 4.6E-69 T 12-10-2018 VAPA_2c07030 9cd17356bb4c4de9d812a95b78347c57 399 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 51 67 5.8E-5 T 12-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 VAPA_2c07030 9cd17356bb4c4de9d812a95b78347c57 399 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 70 88 5.8E-5 T 12-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 VAPA_2c07030 9cd17356bb4c4de9d812a95b78347c57 399 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 287 300 5.8E-5 T 12-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 VAPA_2c07030 9cd17356bb4c4de9d812a95b78347c57 399 Pfam PF13458 Periplasmic binding protein 28 366 7.8E-61 T 12-10-2018 IPR028081 Leucine-binding protein domain VAPA_2c07030 9cd17356bb4c4de9d812a95b78347c57 399 SUPERFAMILY SSF53822 28 389 2.52E-67 T 12-10-2018 IPR028082 Periplasmic binding protein-like I VAPA_2c07030 9cd17356bb4c4de9d812a95b78347c57 399 Gene3D G3DSA:3.40.50.2300 30 350 4.6E-69 T 12-10-2018 VAPA_1c05080 7136e8d1b5ed3a1c99ec10cfd61c03f2 255 Gene3D G3DSA:1.20.120.530 103 236 4.2E-26 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal VAPA_1c05080 7136e8d1b5ed3a1c99ec10cfd61c03f2 255 Pfam PF00392 Bacterial regulatory proteins, gntR family 39 99 2.1E-13 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_1c05080 7136e8d1b5ed3a1c99ec10cfd61c03f2 255 Pfam PF07729 FCD domain 109 230 1.6E-26 T 12-10-2018 IPR011711 GntR, C-terminal VAPA_1c05080 7136e8d1b5ed3a1c99ec10cfd61c03f2 255 Gene3D G3DSA:1.10.10.10 22 100 1.3E-19 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c05080 7136e8d1b5ed3a1c99ec10cfd61c03f2 255 SUPERFAMILY SSF48008 104 235 6.8E-26 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal VAPA_1c05080 7136e8d1b5ed3a1c99ec10cfd61c03f2 255 SMART SM00345 41 99 1.8E-12 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_1c05080 7136e8d1b5ed3a1c99ec10cfd61c03f2 255 SUPERFAMILY SSF46785 33 103 4.67E-16 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c05080 7136e8d1b5ed3a1c99ec10cfd61c03f2 255 SMART SM00895 109 232 7.2E-19 T 12-10-2018 IPR011711 GntR, C-terminal VAPA_1c18990 c0bf8dd12037083e14d800dfca70faed 523 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 213 489 1.3E-45 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 VAPA_1c18990 c0bf8dd12037083e14d800dfca70faed 523 SUPERFAMILY SSF52833 104 196 3.76E-23 T 12-10-2018 IPR036249 Thioredoxin-like superfamily VAPA_1c18990 c0bf8dd12037083e14d800dfca70faed 523 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 464 486 3.0E-41 T 12-10-2018 VAPA_1c18990 c0bf8dd12037083e14d800dfca70faed 523 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 438 454 3.0E-41 T 12-10-2018 VAPA_1c18990 c0bf8dd12037083e14d800dfca70faed 523 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 215 234 3.0E-41 T 12-10-2018 VAPA_1c18990 c0bf8dd12037083e14d800dfca70faed 523 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 312 330 3.0E-41 T 12-10-2018 VAPA_1c18990 c0bf8dd12037083e14d800dfca70faed 523 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 354 372 3.0E-41 T 12-10-2018 VAPA_1c18990 c0bf8dd12037083e14d800dfca70faed 523 Gene3D G3DSA:3.40.30.80 1 200 1.9E-64 T 12-10-2018 VAPA_1c18990 c0bf8dd12037083e14d800dfca70faed 523 Pfam PF13192 Thioredoxin domain 120 195 2.4E-11 T 12-10-2018 IPR012336 Thioredoxin-like fold VAPA_1c18990 c0bf8dd12037083e14d800dfca70faed 523 Gene3D G3DSA:3.50.50.60 324 446 3.9E-109 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c18990 c0bf8dd12037083e14d800dfca70faed 523 Gene3D G3DSA:3.50.50.60 213 504 3.9E-109 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c18990 c0bf8dd12037083e14d800dfca70faed 523 SUPERFAMILY SSF52833 1 102 6.37E-29 T 12-10-2018 IPR036249 Thioredoxin-like superfamily VAPA_1c18990 c0bf8dd12037083e14d800dfca70faed 523 TIGRFAM TIGR03140 AhpF: alkyl hydroperoxide reductase subunit F 1 513 1.0E-239 T 12-10-2018 IPR012081 Alkyl hydroperoxide reductase subunit F GO:0000302|GO:0008785|GO:0050660|GO:0051287 VAPA_1c18990 c0bf8dd12037083e14d800dfca70faed 523 PIRSF PIRSF000238 1 517 4.1E-259 T 12-10-2018 IPR012081 Alkyl hydroperoxide reductase subunit F GO:0000302|GO:0008785|GO:0050660|GO:0051287 VAPA_1c18990 c0bf8dd12037083e14d800dfca70faed 523 SUPERFAMILY SSF51905 197 510 1.89E-50 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c18990 c0bf8dd12037083e14d800dfca70faed 523 ProSitePatterns PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 342 362 - T 12-10-2018 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site GO:0016491|GO:0055114 VAPA_1c18990 c0bf8dd12037083e14d800dfca70faed 523 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 474 492 6.1E-66 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 VAPA_1c18990 c0bf8dd12037083e14d800dfca70faed 523 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 335 347 6.1E-66 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 VAPA_1c18990 c0bf8dd12037083e14d800dfca70faed 523 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 350 374 6.1E-66 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 VAPA_1c18990 c0bf8dd12037083e14d800dfca70faed 523 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 214 236 6.1E-66 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 VAPA_1c18990 c0bf8dd12037083e14d800dfca70faed 523 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 266 276 6.1E-66 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 VAPA_1c18990 c0bf8dd12037083e14d800dfca70faed 523 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 246 261 6.1E-66 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 VAPA_1c18990 c0bf8dd12037083e14d800dfca70faed 523 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 313 321 6.1E-66 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 VAPA_1c18990 c0bf8dd12037083e14d800dfca70faed 523 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 440 461 6.1E-66 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 VAPA_1c18990 c0bf8dd12037083e14d800dfca70faed 523 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 402 418 6.1E-66 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 VAPA_1c42270 4bdf671ebcd19b7f79cc8ebbc01b257a 363 Gene3D G3DSA:3.30.300.130 3 89 5.0E-9 T 12-10-2018 IPR034904 Fe-S cluster assembly domain superfamily VAPA_1c42270 4bdf671ebcd19b7f79cc8ebbc01b257a 363 Pfam PF01883 Iron-sulfur cluster assembly protein 8 76 1.1E-21 T 12-10-2018 IPR002744 MIP18 family-like VAPA_1c42270 4bdf671ebcd19b7f79cc8ebbc01b257a 363 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 96 339 1.2E-104 T 12-10-2018 IPR033756 Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 VAPA_1c42270 4bdf671ebcd19b7f79cc8ebbc01b257a 363 ProSitePatterns PS01215 Mrp family signature. 203 219 - T 12-10-2018 IPR000808 Mrp, conserved site GO:0005524 VAPA_1c42270 4bdf671ebcd19b7f79cc8ebbc01b257a 363 SUPERFAMILY SSF117916 1 83 4.9E-16 T 12-10-2018 IPR034904 Fe-S cluster assembly domain superfamily VAPA_1c42270 4bdf671ebcd19b7f79cc8ebbc01b257a 363 Hamap MF_02040 Iron-sulfur cluster carrier protein. 92 340 37.691 T 12-10-2018 IPR019591 Mrp/NBP35 ATP-binding protein VAPA_1c42270 4bdf671ebcd19b7f79cc8ebbc01b257a 363 SUPERFAMILY SSF52540 90 324 1.95E-62 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c42270 4bdf671ebcd19b7f79cc8ebbc01b257a 363 Gene3D G3DSA:3.40.50.300 90 338 6.2E-87 T 12-10-2018 VAPA_1c38570 42e644ebfd161983674e8d298fccf681 234 SUPERFAMILY SSF47616 102 231 9.05E-32 T 12-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily VAPA_1c38570 42e644ebfd161983674e8d298fccf681 234 SUPERFAMILY SSF52833 12 104 5.49E-23 T 12-10-2018 IPR036249 Thioredoxin-like superfamily VAPA_1c38570 42e644ebfd161983674e8d298fccf681 234 Pfam PF00043 Glutathione S-transferase, C-terminal domain 144 222 2.3E-9 T 12-10-2018 IPR004046 Glutathione S-transferase, C-terminal VAPA_1c38570 42e644ebfd161983674e8d298fccf681 234 Gene3D G3DSA:3.40.30.10 7 231 1.2E-110 T 12-10-2018 VAPA_1c38570 42e644ebfd161983674e8d298fccf681 234 Gene3D G3DSA:1.20.1050.10 106 221 1.2E-110 T 12-10-2018 VAPA_1c38570 42e644ebfd161983674e8d298fccf681 234 Pfam PF02798 Glutathione S-transferase, N-terminal domain 21 98 1.0E-12 T 12-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 VAPA_1c20490 5ed82d0578414458884f472779ab0f6e 332 PIRSF PIRSF017082 4 330 2.2E-82 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c20490 5ed82d0578414458884f472779ab0f6e 332 Gene3D G3DSA:3.40.190.150 38 322 2.6E-109 T 12-10-2018 VAPA_1c20490 5ed82d0578414458884f472779ab0f6e 332 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 57 326 4.6E-86 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c20490 5ed82d0578414458884f472779ab0f6e 332 Gene3D G3DSA:3.40.190.10 135 257 2.6E-109 T 12-10-2018 VAPA_1c20490 5ed82d0578414458884f472779ab0f6e 332 SUPERFAMILY SSF53850 121 292 6.65E-14 T 12-10-2018 VAPA_1c04460 761fb43a0d89917a0e27ab0e8703936d 1569 SUPERFAMILY SSF49299 764 826 4.45E-14 T 12-10-2018 IPR035986 PKD domain superfamily VAPA_1c04460 761fb43a0d89917a0e27ab0e8703936d 1569 SUPERFAMILY SSF46626 1323 1435 2.3E-16 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 VAPA_1c04460 761fb43a0d89917a0e27ab0e8703936d 1569 Gene3D G3DSA:1.10.760.10 1316 1442 5.5E-13 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 VAPA_1c04460 761fb43a0d89917a0e27ab0e8703936d 1569 Pfam PF00652 Ricin-type beta-trefoil lectin domain 1439 1565 1.1E-17 T 12-10-2018 IPR000772 Ricin B, lectin domain VAPA_1c04460 761fb43a0d89917a0e27ab0e8703936d 1569 Gene3D G3DSA:2.60.120.200 583 748 1.7E-25 T 12-10-2018 VAPA_1c04460 761fb43a0d89917a0e27ab0e8703936d 1569 Gene3D G3DSA:2.60.40.10 755 823 5.4E-14 T 12-10-2018 IPR013783 Immunoglobulin-like fold VAPA_1c04460 761fb43a0d89917a0e27ab0e8703936d 1569 SUPERFAMILY SSF50974 824 1161 1.07E-32 T 12-10-2018 IPR011045 Nitrous oxide reductase, N-terminal Reactome: R-HSA-114608 VAPA_1c04460 761fb43a0d89917a0e27ab0e8703936d 1569 SUPERFAMILY SSF46626 1180 1321 2.93E-9 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 VAPA_1c04460 761fb43a0d89917a0e27ab0e8703936d 1569 SUPERFAMILY SSF49899 579 744 1.41E-24 T 12-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily VAPA_1c04460 761fb43a0d89917a0e27ab0e8703936d 1569 Gene3D G3DSA:2.130.10.10 824 995 1.3E-15 T 12-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 VAPA_1c04460 761fb43a0d89917a0e27ab0e8703936d 1569 Gene3D G3DSA:2.130.10.10 996 1168 2.7E-10 T 12-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 VAPA_1c04460 761fb43a0d89917a0e27ab0e8703936d 1569 Pfam PF13205 Bacterial Ig-like domain 433 537 3.1E-16 T 12-10-2018 IPR032812 SbsA, Ig-like domain VAPA_1c04460 761fb43a0d89917a0e27ab0e8703936d 1569 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 598 737 2.5E-18 T 12-10-2018 VAPA_1c04460 761fb43a0d89917a0e27ab0e8703936d 1569 Gene3D G3DSA:2.80.10.50 1443 1567 8.5E-27 T 12-10-2018 VAPA_1c04460 761fb43a0d89917a0e27ab0e8703936d 1569 SMART SM00089 748 829 2.8E-7 T 12-10-2018 IPR022409 PKD/Chitinase domain VAPA_1c04460 761fb43a0d89917a0e27ab0e8703936d 1569 SMART SM00458 1435 1568 2.1E-15 T 12-10-2018 IPR000772 Ricin B, lectin domain VAPA_1c04460 761fb43a0d89917a0e27ab0e8703936d 1569 Pfam PF00801 PKD domain 771 817 4.0E-12 T 12-10-2018 IPR000601 PKD domain VAPA_1c04460 761fb43a0d89917a0e27ab0e8703936d 1569 Gene3D G3DSA:1.10.760.10 1169 1315 4.2E-5 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 VAPA_1c04460 761fb43a0d89917a0e27ab0e8703936d 1569 SUPERFAMILY SSF50370 1439 1566 2.48E-28 T 12-10-2018 IPR035992 Ricin B-like lectins VAPA_1c35360 3da7fe67b60780b3ed62d78c3d1b9515 407 Gene3D G3DSA:1.20.1250.20 9 394 1.3E-48 T 12-10-2018 VAPA_1c35360 3da7fe67b60780b3ed62d78c3d1b9515 407 Pfam PF07690 Major Facilitator Superfamily 14 316 4.7E-29 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 VAPA_1c35360 3da7fe67b60780b3ed62d78c3d1b9515 407 SUPERFAMILY SSF103473 10 391 3.01E-60 T 12-10-2018 IPR036259 MFS transporter superfamily VAPA_2c06010 deea020a72c0ce14240ae9e001d3186b 351 Gene3D G3DSA:3.40.50.970 99 242 9.4E-20 T 12-10-2018 VAPA_2c06010 deea020a72c0ce14240ae9e001d3186b 351 SUPERFAMILY SSF52518 18 239 3.3E-60 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold VAPA_2c06010 deea020a72c0ce14240ae9e001d3186b 351 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 66 214 1.1E-21 T 12-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 VAPA_1c15710 e438b94216451a2fc1a73cc9bdb2c968 362 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 8 359 54.229 T 12-10-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 VAPA_1c15710 e438b94216451a2fc1a73cc9bdb2c968 362 Gene3D G3DSA:3.90.1150.10 24 347 5.4E-106 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 VAPA_1c15710 e438b94216451a2fc1a73cc9bdb2c968 362 Pfam PF00155 Aminotransferase class I and II 29 355 3.8E-58 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 VAPA_1c15710 e438b94216451a2fc1a73cc9bdb2c968 362 TIGRFAM TIGR01141 hisC: histidinol-phosphate transaminase 12 358 3.2E-90 T 12-10-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 VAPA_1c15710 e438b94216451a2fc1a73cc9bdb2c968 362 SUPERFAMILY SSF53383 9 359 3.79E-80 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase VAPA_1c15710 e438b94216451a2fc1a73cc9bdb2c968 362 Gene3D G3DSA:3.40.640.10 42 267 5.4E-106 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 VAPA_1c15710 e438b94216451a2fc1a73cc9bdb2c968 362 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 215 224 - T 12-10-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0016740 VAPA_1c45520 3b11a26c0527553ad6d994dd0c8fb221 313 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 59 309 7.8E-31 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 VAPA_1c45520 3b11a26c0527553ad6d994dd0c8fb221 313 SUPERFAMILY SSF88659 222 311 1.44E-14 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like VAPA_1c45520 3b11a26c0527553ad6d994dd0c8fb221 313 Pfam PF04545 Sigma-70, region 4 251 307 2.0E-13 T 12-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 VAPA_1c45520 3b11a26c0527553ad6d994dd0c8fb221 313 Pfam PF04542 Sigma-70 region 2 64 133 4.1E-17 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 VAPA_1c45520 3b11a26c0527553ad6d994dd0c8fb221 313 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 279 305 - T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 VAPA_1c45520 3b11a26c0527553ad6d994dd0c8fb221 313 Hamap MF_00961 RNA polymerase sigma factor RpoH [rpoH]. 12 311 48.987 T 12-10-2018 IPR012759 RNA polymerase sigma factor RpoH, proteobacteria GO:0003700|GO:0006352|GO:0006355|GO:0016987 VAPA_1c45520 3b11a26c0527553ad6d994dd0c8fb221 313 PRINTS PR00046 Major sigma-70 factor signature 112 120 2.4E-15 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 VAPA_1c45520 3b11a26c0527553ad6d994dd0c8fb221 313 PRINTS PR00046 Major sigma-70 factor signature 294 305 2.4E-15 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 VAPA_1c45520 3b11a26c0527553ad6d994dd0c8fb221 313 PRINTS PR00046 Major sigma-70 factor signature 279 294 2.4E-15 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 VAPA_1c45520 3b11a26c0527553ad6d994dd0c8fb221 313 PRINTS PR00046 Major sigma-70 factor signature 88 101 2.4E-15 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 VAPA_1c45520 3b11a26c0527553ad6d994dd0c8fb221 313 TIGRFAM TIGR02392 rpoH_proteo: alternative sigma factor RpoH 25 310 2.5E-117 T 12-10-2018 IPR012759 RNA polymerase sigma factor RpoH, proteobacteria GO:0003700|GO:0006352|GO:0006355|GO:0016987 VAPA_1c45520 3b11a26c0527553ad6d994dd0c8fb221 313 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 88 101 - T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 VAPA_1c45520 3b11a26c0527553ad6d994dd0c8fb221 313 Gene3D G3DSA:1.10.601.10 19 136 2.7E-29 T 12-10-2018 VAPA_1c45520 3b11a26c0527553ad6d994dd0c8fb221 313 Gene3D G3DSA:1.20.140.160 150 311 5.4E-13 T 12-10-2018 VAPA_1c45520 3b11a26c0527553ad6d994dd0c8fb221 313 SUPERFAMILY SSF88946 26 133 1.7E-39 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 VAPA_1c05890 391dd614512764dcf978f41f9841144c 629 Pfam PF00512 His Kinase A (phospho-acceptor) domain 252 317 9.2E-10 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 VAPA_1c05890 391dd614512764dcf978f41f9841144c 629 Pfam PF00672 HAMP domain 175 222 2.4E-6 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 VAPA_1c05890 391dd614512764dcf978f41f9841144c 629 SUPERFAMILY SSF52172 497 620 7.83E-20 T 12-10-2018 IPR011006 CheY-like superfamily VAPA_1c05890 391dd614512764dcf978f41f9841144c 629 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 364 471 1.3E-19 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase VAPA_1c05890 391dd614512764dcf978f41f9841144c 629 SMART SM00388 252 317 4.1E-13 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 VAPA_1c05890 391dd614512764dcf978f41f9841144c 629 Gene3D G3DSA:1.20.1480.50 136 233 3.0E-6 T 12-10-2018 VAPA_1c05890 391dd614512764dcf978f41f9841144c 629 SMART SM00448 499 616 2.7E-14 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_1c05890 391dd614512764dcf978f41f9841144c 629 Gene3D G3DSA:3.40.50.2300 489 626 9.5E-19 T 12-10-2018 VAPA_1c05890 391dd614512764dcf978f41f9841144c 629 Pfam PF00072 Response regulator receiver domain 501 617 5.4E-13 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_1c05890 391dd614512764dcf978f41f9841144c 629 SMART SM00387 361 475 1.2E-23 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase VAPA_1c05890 391dd614512764dcf978f41f9841144c 629 SUPERFAMILY SSF47384 238 317 1.96E-14 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 VAPA_1c05890 391dd614512764dcf978f41f9841144c 629 SMART SM00304 175 226 2.4E-4 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 VAPA_1c05890 391dd614512764dcf978f41f9841144c 629 Gene3D G3DSA:1.10.287.130 238 319 1.0E-14 T 12-10-2018 VAPA_1c05890 391dd614512764dcf978f41f9841144c 629 SUPERFAMILY SSF55874 307 471 9.04E-36 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_1c05890 391dd614512764dcf978f41f9841144c 629 Gene3D G3DSA:3.30.565.10 322 475 6.8E-33 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_1c33940 5aade143cae691529c69db676ea5f6ad 224 Gene3D G3DSA:1.10.10.10 124 223 2.3E-27 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c33940 5aade143cae691529c69db676ea5f6ad 224 SMART SM00862 145 216 5.3E-23 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 VAPA_1c33940 5aade143cae691529c69db676ea5f6ad 224 SUPERFAMILY SSF52172 2 172 4.38E-35 T 12-10-2018 IPR011006 CheY-like superfamily VAPA_1c33940 5aade143cae691529c69db676ea5f6ad 224 Pfam PF00072 Response regulator receiver domain 3 112 1.7E-19 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_1c33940 5aade143cae691529c69db676ea5f6ad 224 Gene3D G3DSA:3.40.50.2300 1 122 2.1E-34 T 12-10-2018 VAPA_1c33940 5aade143cae691529c69db676ea5f6ad 224 Pfam PF00486 Transcriptional regulatory protein, C terminal 145 216 2.6E-20 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 VAPA_1c33940 5aade143cae691529c69db676ea5f6ad 224 SMART SM00448 1 112 8.6E-31 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_1c41370 703b2f25ed4647e3c75ed3be9e515d70 140 SUPERFAMILY SSF159888 20 129 3.01E-17 T 12-10-2018 VAPA_1c41370 703b2f25ed4647e3c75ed3be9e515d70 140 Pfam PF08818 Domain of unknown function (DU1801) 29 123 2.6E-19 T 12-10-2018 IPR014922 Domain of unknown function DUF1801 VAPA_1c07340 dbc298636c1a3d09baa33e999b706f41 397 Gene3D G3DSA:2.40.30.10 340 395 3.3E-29 T 12-10-2018 VAPA_1c07340 dbc298636c1a3d09baa33e999b706f41 397 PRINTS PR00315 GTP-binding elongation factor signature 131 140 7.7E-25 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 VAPA_1c07340 dbc298636c1a3d09baa33e999b706f41 397 PRINTS PR00315 GTP-binding elongation factor signature 58 66 7.7E-25 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 VAPA_1c07340 dbc298636c1a3d09baa33e999b706f41 397 PRINTS PR00315 GTP-binding elongation factor signature 94 105 7.7E-25 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 VAPA_1c07340 dbc298636c1a3d09baa33e999b706f41 397 PRINTS PR00315 GTP-binding elongation factor signature 78 88 7.7E-25 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 VAPA_1c07340 dbc298636c1a3d09baa33e999b706f41 397 PRINTS PR00315 GTP-binding elongation factor signature 14 27 7.7E-25 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 VAPA_1c07340 dbc298636c1a3d09baa33e999b706f41 397 SUPERFAMILY SSF52540 6 221 1.07E-59 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c07340 dbc298636c1a3d09baa33e999b706f41 397 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 12-10-2018 IPR031157 Tr-type G domain, conserved site VAPA_1c07340 dbc298636c1a3d09baa33e999b706f41 397 Pfam PF03143 Elongation factor Tu C-terminal domain 300 394 4.1E-34 T 12-10-2018 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal VAPA_1c07340 dbc298636c1a3d09baa33e999b706f41 397 SUPERFAMILY SSF50465 300 395 8.39E-37 T 12-10-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal VAPA_1c07340 dbc298636c1a3d09baa33e999b706f41 397 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 13 149 1.0E-14 T 12-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 VAPA_1c07340 dbc298636c1a3d09baa33e999b706f41 397 Gene3D G3DSA:2.40.30.10 208 336 5.4E-53 T 12-10-2018 VAPA_1c07340 dbc298636c1a3d09baa33e999b706f41 397 SUPERFAMILY SSF50447 207 303 1.22E-29 T 12-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily VAPA_1c07340 dbc298636c1a3d09baa33e999b706f41 397 Hamap MF_00118_B Elongation factor Tu [tuf]. 1 396 59.596 T 12-10-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 VAPA_1c07340 dbc298636c1a3d09baa33e999b706f41 397 Gene3D G3DSA:3.40.50.300 1 205 9.2E-69 T 12-10-2018 VAPA_1c07340 dbc298636c1a3d09baa33e999b706f41 397 Pfam PF03144 Elongation factor Tu domain 2 227 296 1.5E-15 T 12-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 VAPA_1c07340 dbc298636c1a3d09baa33e999b706f41 397 TIGRFAM TIGR00485 EF-Tu: translation elongation factor Tu 1 395 3.8E-225 T 12-10-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 VAPA_1c07340 dbc298636c1a3d09baa33e999b706f41 397 Pfam PF00009 Elongation factor Tu GTP binding domain 10 203 2.1E-58 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 VAPA_1c50990 dbc298636c1a3d09baa33e999b706f41 397 Gene3D G3DSA:2.40.30.10 340 395 3.3E-29 T 12-10-2018 VAPA_1c50990 dbc298636c1a3d09baa33e999b706f41 397 PRINTS PR00315 GTP-binding elongation factor signature 131 140 7.7E-25 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 VAPA_1c50990 dbc298636c1a3d09baa33e999b706f41 397 PRINTS PR00315 GTP-binding elongation factor signature 58 66 7.7E-25 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 VAPA_1c50990 dbc298636c1a3d09baa33e999b706f41 397 PRINTS PR00315 GTP-binding elongation factor signature 94 105 7.7E-25 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 VAPA_1c50990 dbc298636c1a3d09baa33e999b706f41 397 PRINTS PR00315 GTP-binding elongation factor signature 78 88 7.7E-25 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 VAPA_1c50990 dbc298636c1a3d09baa33e999b706f41 397 PRINTS PR00315 GTP-binding elongation factor signature 14 27 7.7E-25 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 VAPA_1c50990 dbc298636c1a3d09baa33e999b706f41 397 SUPERFAMILY SSF52540 6 221 1.07E-59 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c50990 dbc298636c1a3d09baa33e999b706f41 397 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 12-10-2018 IPR031157 Tr-type G domain, conserved site VAPA_1c50990 dbc298636c1a3d09baa33e999b706f41 397 Pfam PF03143 Elongation factor Tu C-terminal domain 300 394 4.1E-34 T 12-10-2018 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal VAPA_1c50990 dbc298636c1a3d09baa33e999b706f41 397 SUPERFAMILY SSF50465 300 395 8.39E-37 T 12-10-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal VAPA_1c50990 dbc298636c1a3d09baa33e999b706f41 397 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 13 149 1.0E-14 T 12-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 VAPA_1c50990 dbc298636c1a3d09baa33e999b706f41 397 Gene3D G3DSA:2.40.30.10 208 336 5.4E-53 T 12-10-2018 VAPA_1c50990 dbc298636c1a3d09baa33e999b706f41 397 SUPERFAMILY SSF50447 207 303 1.22E-29 T 12-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily VAPA_1c50990 dbc298636c1a3d09baa33e999b706f41 397 Hamap MF_00118_B Elongation factor Tu [tuf]. 1 396 59.596 T 12-10-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 VAPA_1c50990 dbc298636c1a3d09baa33e999b706f41 397 Gene3D G3DSA:3.40.50.300 1 205 9.2E-69 T 12-10-2018 VAPA_1c50990 dbc298636c1a3d09baa33e999b706f41 397 Pfam PF03144 Elongation factor Tu domain 2 227 296 1.5E-15 T 12-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 VAPA_1c50990 dbc298636c1a3d09baa33e999b706f41 397 TIGRFAM TIGR00485 EF-Tu: translation elongation factor Tu 1 395 3.8E-225 T 12-10-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 VAPA_1c50990 dbc298636c1a3d09baa33e999b706f41 397 Pfam PF00009 Elongation factor Tu GTP binding domain 10 203 2.1E-58 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 VAPA_2c11010 537fb79dd8f5aed63fb82591b124c867 187 Gene3D G3DSA:3.30.40.60 78 160 3.2E-21 T 12-10-2018 VAPA_2c11010 537fb79dd8f5aed63fb82591b124c867 187 SMART SM00507 81 134 1.1E-8 T 12-10-2018 IPR003615 HNH nuclease VAPA_2c11010 537fb79dd8f5aed63fb82591b124c867 187 Pfam PF14279 HNH endonuclease 94 147 8.4E-16 T 12-10-2018 IPR029471 HNH endonuclease 5 VAPA_1c12320 ccd85a3b971689124bd34032953d13d0 435 SUPERFAMILY SSF118215 10 405 3.92E-111 T 12-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 VAPA_1c12320 ccd85a3b971689124bd34032953d13d0 435 Gene3D G3DSA:1.10.3860.10 2 418 1.4E-115 T 12-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 VAPA_1c12320 ccd85a3b971689124bd34032953d13d0 435 PRINTS PR00173 Glutamate-aspartate symporter signature 5 25 2.0E-34 T 12-10-2018 VAPA_1c12320 ccd85a3b971689124bd34032953d13d0 435 PRINTS PR00173 Glutamate-aspartate symporter signature 358 378 2.0E-34 T 12-10-2018 VAPA_1c12320 ccd85a3b971689124bd34032953d13d0 435 PRINTS PR00173 Glutamate-aspartate symporter signature 196 215 2.0E-34 T 12-10-2018 VAPA_1c12320 ccd85a3b971689124bd34032953d13d0 435 PRINTS PR00173 Glutamate-aspartate symporter signature 331 350 2.0E-34 T 12-10-2018 VAPA_1c12320 ccd85a3b971689124bd34032953d13d0 435 PRINTS PR00173 Glutamate-aspartate symporter signature 149 171 2.0E-34 T 12-10-2018 VAPA_1c12320 ccd85a3b971689124bd34032953d13d0 435 PRINTS PR00173 Glutamate-aspartate symporter signature 296 322 2.0E-34 T 12-10-2018 VAPA_1c12320 ccd85a3b971689124bd34032953d13d0 435 PRINTS PR00173 Glutamate-aspartate symporter signature 82 107 2.0E-34 T 12-10-2018 VAPA_1c12320 ccd85a3b971689124bd34032953d13d0 435 PRINTS PR00173 Glutamate-aspartate symporter signature 52 72 2.0E-34 T 12-10-2018 VAPA_1c12320 ccd85a3b971689124bd34032953d13d0 435 Pfam PF00375 Sodium:dicarboxylate symporter family 9 404 4.4E-109 T 12-10-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 VAPA_1c42470 87c351abf064bbb2e8e1bba39fe2fe49 523 SUPERFAMILY SSF56425 227 342 1.48E-43 T 12-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 VAPA_1c42470 87c351abf064bbb2e8e1bba39fe2fe49 523 Pfam PF00890 FAD binding domain 5 381 2.5E-102 T 12-10-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 VAPA_1c42470 87c351abf064bbb2e8e1bba39fe2fe49 523 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 3.7E-8 T 12-10-2018 VAPA_1c42470 87c351abf064bbb2e8e1bba39fe2fe49 523 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 344 366 3.7E-8 T 12-10-2018 VAPA_1c42470 87c351abf064bbb2e8e1bba39fe2fe49 523 Gene3D G3DSA:3.50.50.60 5 392 5.7E-160 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c42470 87c351abf064bbb2e8e1bba39fe2fe49 523 PIRSF PIRSF000171 1 519 1.8E-35 T 12-10-2018 VAPA_1c42470 87c351abf064bbb2e8e1bba39fe2fe49 523 SUPERFAMILY SSF51905 2 435 1.94E-72 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c42470 87c351abf064bbb2e8e1bba39fe2fe49 523 Pfam PF02910 Fumarate reductase flavoprotein C-term 428 507 1.9E-14 T 12-10-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 VAPA_1c42470 87c351abf064bbb2e8e1bba39fe2fe49 523 Gene3D G3DSA:3.90.700.10 237 347 5.7E-160 T 12-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 VAPA_1c42470 87c351abf064bbb2e8e1bba39fe2fe49 523 SUPERFAMILY SSF46977 412 510 9.16E-31 T 12-10-2018 IPR037099 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain superfamily GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 VAPA_1c42470 87c351abf064bbb2e8e1bba39fe2fe49 523 Gene3D G3DSA:1.20.58.100 412 523 6.7E-42 T 12-10-2018 VAPA_1c42470 87c351abf064bbb2e8e1bba39fe2fe49 523 TIGRFAM TIGR00551 nadB: L-aspartate oxidase 3 507 2.0E-195 T 12-10-2018 IPR005288 L-aspartate oxidase GO:0005737|GO:0008734|GO:0009435|GO:0055114 KEGG: 00250+1.4.3.16|KEGG: 00760+1.4.3.16|MetaCyc: PWY-5316|MetaCyc: PWY-7342 VAPA_2c06710 59dbeab15b0d0b2a8f1463dbabc4eed6 161 SUPERFAMILY SSF55298 1 158 1.43E-35 T 12-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 VAPA_2c06710 59dbeab15b0d0b2a8f1463dbabc4eed6 161 Pfam PF14588 YjgF/chorismate_mutase-like, putative endoribonuclease 5 151 3.0E-20 T 12-10-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like VAPA_2c06710 59dbeab15b0d0b2a8f1463dbabc4eed6 161 Gene3D G3DSA:3.30.1330.40 1 158 2.7E-44 T 12-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 VAPA_1c20670 12cbdb280706a3f023988fe3a7defac6 424 SUPERFAMILY SSF53756 218 360 9.42E-6 T 12-10-2018 VAPA_1c18160 f5ab11dfd955a593e8cccced1c551f9a 324 Gene3D G3DSA:3.40.190.10 128 249 6.5E-101 T 12-10-2018 VAPA_1c18160 f5ab11dfd955a593e8cccced1c551f9a 324 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 49 320 2.2E-70 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c18160 f5ab11dfd955a593e8cccced1c551f9a 324 Gene3D G3DSA:3.40.190.150 30 314 6.5E-101 T 12-10-2018 VAPA_1c18160 f5ab11dfd955a593e8cccced1c551f9a 324 PIRSF PIRSF017082 1 323 5.8E-69 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c18160 f5ab11dfd955a593e8cccced1c551f9a 324 SUPERFAMILY SSF53850 114 279 3.8E-8 T 12-10-2018 VAPA_1c24660 440f94a3abb7107daa1053c9dbda4b78 412 SUPERFAMILY SSF160996 207 351 2.09E-11 T 12-10-2018 VAPA_1c24660 440f94a3abb7107daa1053c9dbda4b78 412 TIGRFAM TIGR00275 TIGR00275: flavoprotein, HI0933 family 7 404 2.5E-87 T 12-10-2018 IPR004792 Conserved hypothetical protein CHP00275, flavoprotein HI0933-like VAPA_1c24660 440f94a3abb7107daa1053c9dbda4b78 412 PRINTS PR00419 Adrenodoxin reductase family signature 6 28 6.8E-7 T 12-10-2018 VAPA_1c24660 440f94a3abb7107daa1053c9dbda4b78 412 PRINTS PR00419 Adrenodoxin reductase family signature 29 42 6.8E-7 T 12-10-2018 VAPA_1c24660 440f94a3abb7107daa1053c9dbda4b78 412 Gene3D G3DSA:1.10.8.260 280 335 2.0E-69 T 12-10-2018 IPR023166 HI0933-like insert domain superfamily VAPA_1c24660 440f94a3abb7107daa1053c9dbda4b78 412 Gene3D G3DSA:3.50.50.60 9 400 2.0E-69 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c24660 440f94a3abb7107daa1053c9dbda4b78 412 Gene3D G3DSA:2.40.30.10 195 352 2.0E-69 T 12-10-2018 VAPA_1c24660 440f94a3abb7107daa1053c9dbda4b78 412 SUPERFAMILY SSF51905 1 407 1.21E-42 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c24660 440f94a3abb7107daa1053c9dbda4b78 412 Pfam PF03486 HI0933-like protein 6 404 2.9E-110 T 12-10-2018 VAPA_1c24660 440f94a3abb7107daa1053c9dbda4b78 412 TIGRFAM TIGR03862 flavo_PP4765: flavoprotein, TIGR03862 family 27 408 1.5E-162 T 12-10-2018 IPR022460 Conserved hyptotheical protein CHP03862, flavoprotein, PP4765 VAPA_1c11730 27927171bdacbcf4e2e5186fd352464c 492 SUPERFAMILY SSF53067 2 245 5.02E-69 T 12-10-2018 VAPA_1c11730 27927171bdacbcf4e2e5186fd352464c 492 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 1 245 9.5E-71 T 12-10-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 VAPA_1c11730 27927171bdacbcf4e2e5186fd352464c 492 Gene3D G3DSA:3.30.420.40 1 246 1.8E-82 T 12-10-2018 VAPA_1c11730 27927171bdacbcf4e2e5186fd352464c 492 TIGRFAM TIGR01312 XylB: xylulokinase 3 482 4.9E-166 T 12-10-2018 IPR006000 Xylulokinase GO:0004856|GO:0005997 KEGG: 00040+2.7.1.17 VAPA_1c11730 27927171bdacbcf4e2e5186fd352464c 492 ProSitePatterns PS00933 FGGY family of carbohydrate kinases signature 1. 128 140 - T 12-10-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 VAPA_1c11730 27927171bdacbcf4e2e5186fd352464c 492 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 256 443 5.4E-33 T 12-10-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 VAPA_1c11730 27927171bdacbcf4e2e5186fd352464c 492 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 354 374 - T 12-10-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 VAPA_1c11730 27927171bdacbcf4e2e5186fd352464c 492 SUPERFAMILY SSF53067 247 488 2.05E-57 T 12-10-2018 VAPA_1c11730 27927171bdacbcf4e2e5186fd352464c 492 Gene3D G3DSA:3.30.420.40 247 489 1.4E-71 T 12-10-2018 VAPA_1c11730 27927171bdacbcf4e2e5186fd352464c 492 PIRSF PIRSF000538 1 492 2.7E-128 T 12-10-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 VAPA_1c15520 9b3b7c2acbec12984531684502b5e396 139 Gene3D G3DSA:3.30.70.1060 1 118 4.3E-34 T 12-10-2018 VAPA_1c15520 9b3b7c2acbec12984531684502b5e396 139 Pfam PF03795 YCII-related domain 1 116 8.8E-23 T 12-10-2018 IPR005545 YCII-related VAPA_1c15520 9b3b7c2acbec12984531684502b5e396 139 SUPERFAMILY SSF54909 1 118 3.22E-33 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel VAPA_1c15270 af93676ab5d5baedf1aa2bc41c749187 332 Gene3D G3DSA:3.20.20.60 1 267 4.0E-92 T 12-10-2018 VAPA_1c15270 af93676ab5d5baedf1aa2bc41c749187 332 SUPERFAMILY SSF51621 50 265 3.84E-43 T 12-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 VAPA_1c15270 af93676ab5d5baedf1aa2bc41c749187 332 PIRSF PIRSF015582 41 323 5.1E-49 T 12-10-2018 IPR011206 Citrate lyase beta subunit-like VAPA_1c15270 af93676ab5d5baedf1aa2bc41c749187 332 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 41 255 1.7E-18 T 12-10-2018 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 VAPA_1c04320 c344a4950696400b7508e1921f841582 239 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_1c04320 c344a4950696400b7508e1921f841582 239 SUPERFAMILY SSF52540 5 236 4.53E-56 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c04320 c344a4950696400b7508e1921f841582 239 Gene3D G3DSA:3.40.50.300 1 239 9.8E-61 T 12-10-2018 VAPA_1c04320 c344a4950696400b7508e1921f841582 239 Pfam PF00005 ABC transporter 22 166 6.6E-29 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c04320 c344a4950696400b7508e1921f841582 239 SMART SM00382 30 218 3.2E-9 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c22940 757b4fb7bced6b2e57887b12419771de 215 Pfam PF07729 FCD domain 83 208 9.0E-25 T 12-10-2018 IPR011711 GntR, C-terminal VAPA_1c22940 757b4fb7bced6b2e57887b12419771de 215 Gene3D G3DSA:1.20.120.530 77 215 3.3E-26 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal VAPA_1c22940 757b4fb7bced6b2e57887b12419771de 215 SUPERFAMILY SSF46785 8 77 4.49E-21 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c22940 757b4fb7bced6b2e57887b12419771de 215 SUPERFAMILY SSF48008 79 211 7.32E-23 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal VAPA_1c22940 757b4fb7bced6b2e57887b12419771de 215 Pfam PF00392 Bacterial regulatory proteins, gntR family 11 73 1.8E-19 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_1c22940 757b4fb7bced6b2e57887b12419771de 215 Gene3D G3DSA:1.10.10.10 9 75 2.4E-22 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c22940 757b4fb7bced6b2e57887b12419771de 215 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 33 47 1.0E-6 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_1c22940 757b4fb7bced6b2e57887b12419771de 215 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 47 63 1.0E-6 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_1c22940 757b4fb7bced6b2e57887b12419771de 215 SMART SM00345 15 73 1.1E-16 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_1c22940 757b4fb7bced6b2e57887b12419771de 215 SMART SM00895 83 209 1.0E-18 T 12-10-2018 IPR011711 GntR, C-terminal VAPA_1c34580 28da639a03a67f0a81b9c48d337f469a 324 SUPERFAMILY SSF46785 17 128 1.25E-16 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c34580 28da639a03a67f0a81b9c48d337f469a 324 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 20 79 5.9E-12 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c34580 28da639a03a67f0a81b9c48d337f469a 324 Pfam PF03466 LysR substrate binding domain 104 311 2.3E-31 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_1c34580 28da639a03a67f0a81b9c48d337f469a 324 Gene3D G3DSA:3.40.190.10 110 302 1.5E-39 T 12-10-2018 VAPA_1c34580 28da639a03a67f0a81b9c48d337f469a 324 SUPERFAMILY SSF53850 107 315 3.88E-33 T 12-10-2018 VAPA_1c34580 28da639a03a67f0a81b9c48d337f469a 324 Gene3D G3DSA:1.10.10.10 17 105 8.8E-15 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c34580 28da639a03a67f0a81b9c48d337f469a 324 Gene3D G3DSA:3.40.190.10 183 285 1.5E-39 T 12-10-2018 VAPA_1c04560 d0dc7a74e4897049736cf0c2c8982e03 1035 SUPERFAMILY SSF52540 43 627 1.02E-49 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c04560 d0dc7a74e4897049736cf0c2c8982e03 1035 SUPERFAMILY SSF52540 717 1009 8.34E-51 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c04560 d0dc7a74e4897049736cf0c2c8982e03 1035 Gene3D G3DSA:3.30.190.20 169 285 1.2E-241 T 12-10-2018 VAPA_1c04560 d0dc7a74e4897049736cf0c2c8982e03 1035 ProSitePatterns PS00211 ABC transporters family signature. 925 939 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_1c04560 d0dc7a74e4897049736cf0c2c8982e03 1035 Hamap MF_00205 UvrABC system protein A [uvrA]. 40 1035 21.938 T 12-10-2018 IPR004602 UvrABC system subunit A GO:0003677|GO:0006289|GO:0009380|GO:0016887 VAPA_1c04560 d0dc7a74e4897049736cf0c2c8982e03 1035 ProSitePatterns PS00211 ABC transporters family signature. 545 559 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_1c04560 d0dc7a74e4897049736cf0c2c8982e03 1035 TIGRFAM TIGR00630 uvra: excinuclease ABC subunit A 42 664 1.5E-251 T 12-10-2018 IPR004602 UvrABC system subunit A GO:0003677|GO:0006289|GO:0009380|GO:0016887 VAPA_1c04560 d0dc7a74e4897049736cf0c2c8982e03 1035 Gene3D G3DSA:1.20.1580.10 129 550 1.2E-241 T 12-10-2018 VAPA_1c04560 d0dc7a74e4897049736cf0c2c8982e03 1035 Gene3D G3DSA:1.20.1580.10 788 925 1.4E-140 T 12-10-2018 VAPA_1c04560 d0dc7a74e4897049736cf0c2c8982e03 1035 Gene3D G3DSA:3.40.50.300 709 1031 1.4E-140 T 12-10-2018 VAPA_1c04560 d0dc7a74e4897049736cf0c2c8982e03 1035 Gene3D G3DSA:1.10.8.280 328 448 1.2E-241 T 12-10-2018 VAPA_1c04560 d0dc7a74e4897049736cf0c2c8982e03 1035 Gene3D G3DSA:3.40.50.300 45 652 1.2E-241 T 12-10-2018 VAPA_1c44880 c8834cf4b42d4e2430f50b83531acf50 382 Pfam PF13356 Arm DNA-binding domain 3 73 4.7E-12 T 12-10-2018 IPR025166 Integrase, DNA-binding domain VAPA_1c44880 c8834cf4b42d4e2430f50b83531acf50 382 Gene3D G3DSA:1.10.443.10 190 366 1.0E-12 T 12-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 VAPA_1c44880 c8834cf4b42d4e2430f50b83531acf50 382 Gene3D G3DSA:1.10.150.130 78 189 2.5E-21 T 12-10-2018 IPR010998 Integrase/recombinase, N-terminal VAPA_1c44880 c8834cf4b42d4e2430f50b83531acf50 382 SUPERFAMILY SSF56349 82 366 2.38E-51 T 12-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 VAPA_1c44880 c8834cf4b42d4e2430f50b83531acf50 382 Pfam PF00589 Phage integrase family 194 356 2.2E-16 T 12-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 VAPA_1c44880 c8834cf4b42d4e2430f50b83531acf50 382 Gene3D G3DSA:3.30.160.390 1 77 5.6E-25 T 12-10-2018 IPR038488 Integrase, DNA-binding domain superfamily VAPA_1c41330 65fb3ebc1667ff2dd86fcfd393f99fde 688 Pfam PF13722 5TM C-terminal transporter carbon starvation CstA 463 591 1.7E-34 T 12-10-2018 IPR025299 CstA, C-terminal domain VAPA_1c41330 65fb3ebc1667ff2dd86fcfd393f99fde 688 Pfam PF02554 Carbon starvation protein CstA 32 409 2.6E-171 T 12-10-2018 IPR003706 CstA, N-terminal domain GO:0009267|GO:0016020 VAPA_1c34860 a30e81cf745277d0ab18b95739fcf82a 576 Gene3D G3DSA:3.40.190.10 82 464 4.9E-49 T 12-10-2018 VAPA_1c34860 a30e81cf745277d0ab18b95739fcf82a 576 PIRSF PIRSF035859 1 575 9.0E-301 T 12-10-2018 IPR014597 ABC transporter, periplasmic substrate-binding protein, predicted GO:0005215 VAPA_1c34860 a30e81cf745277d0ab18b95739fcf82a 576 Gene3D G3DSA:3.40.190.10 186 507 4.9E-49 T 12-10-2018 VAPA_1c34860 a30e81cf745277d0ab18b95739fcf82a 576 SUPERFAMILY SSF53850 62 516 1.41E-59 T 12-10-2018 VAPA_1c28920 904459d97c98e5fd6afc568b22f33e20 426 Pfam PF07969 Amidohydrolase family 42 381 9.9E-40 T 12-10-2018 IPR013108 Amidohydrolase 3 VAPA_1c28920 904459d97c98e5fd6afc568b22f33e20 426 SUPERFAMILY SSF51338 1 64 7.68E-15 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 VAPA_1c28920 904459d97c98e5fd6afc568b22f33e20 426 Gene3D G3DSA:3.20.20.140 53 360 1.3E-157 T 12-10-2018 VAPA_1c28920 904459d97c98e5fd6afc568b22f33e20 426 SUPERFAMILY SSF51556 53 370 2.64E-106 T 12-10-2018 IPR032466 Metal-dependent hydrolase VAPA_1c28920 904459d97c98e5fd6afc568b22f33e20 426 Gene3D G3DSA:2.30.40.10 8 404 1.3E-157 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 VAPA_1c28570 7f8edd63a4b85c5197290c28293206e7 201 Gene3D G3DSA:3.90.950.10 2 200 3.7E-65 T 12-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like VAPA_1c28570 7f8edd63a4b85c5197290c28293206e7 201 PIRSF PIRSF006305 2 201 1.2E-43 T 12-10-2018 IPR003697 Maf-like protein GO:0047429 VAPA_1c28570 7f8edd63a4b85c5197290c28293206e7 201 Pfam PF02545 Maf-like protein 6 196 3.3E-48 T 12-10-2018 IPR003697 Maf-like protein GO:0047429 VAPA_1c28570 7f8edd63a4b85c5197290c28293206e7 201 Hamap MF_00528 Septum formation protein Maf [maf]. 5 201 28.554 T 12-10-2018 IPR003697 Maf-like protein GO:0047429 VAPA_1c28570 7f8edd63a4b85c5197290c28293206e7 201 SUPERFAMILY SSF52972 5 195 9.81E-52 T 12-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like VAPA_1c28570 7f8edd63a4b85c5197290c28293206e7 201 TIGRFAM TIGR00172 maf: septum formation protein Maf 6 195 1.0E-42 T 12-10-2018 IPR003697 Maf-like protein GO:0047429 VAPA_1c43780 f50d7856ca69512ac20ab74f84dffb9a 577 SMART SM00382 328 451 4.3E-4 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c43780 f50d7856ca69512ac20ab74f84dffb9a 577 Pfam PF05157 Type II secretion system (T2SS), protein E, N-terminal domain 54 152 8.6E-18 T 12-10-2018 IPR007831 General secretory system II, protein E, N-terminal VAPA_1c43780 f50d7856ca69512ac20ab74f84dffb9a 577 Gene3D G3DSA:3.40.50.300 305 577 3.9E-102 T 12-10-2018 VAPA_1c43780 f50d7856ca69512ac20ab74f84dffb9a 577 SUPERFAMILY SSF52540 189 574 9.87E-94 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c43780 f50d7856ca69512ac20ab74f84dffb9a 577 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 395 409 - T 12-10-2018 IPR001482 Type II/IV secretion system protein VAPA_1c43780 f50d7856ca69512ac20ab74f84dffb9a 577 TIGRFAM TIGR02538 type_IV_pilB: type IV-A pilus assembly ATPase PilB 18 576 5.7E-240 T 12-10-2018 IPR013374 ATPase, type IV, pilus assembly, PilB GO:0005524|GO:0008565|GO:0009297 VAPA_1c43780 f50d7856ca69512ac20ab74f84dffb9a 577 Gene3D G3DSA:3.30.300.160 73 152 3.5E-8 T 12-10-2018 VAPA_1c43780 f50d7856ca69512ac20ab74f84dffb9a 577 Pfam PF00437 Type II/IV secretion system protein 207 467 2.1E-86 T 12-10-2018 IPR001482 Type II/IV secretion system protein VAPA_1c43780 f50d7856ca69512ac20ab74f84dffb9a 577 SUPERFAMILY SSF160246 14 150 1.02E-30 T 12-10-2018 IPR037257 General secretory system II, protein E, N-terminal superfamily VAPA_1c43780 f50d7856ca69512ac20ab74f84dffb9a 577 Gene3D G3DSA:3.30.450.90 166 300 1.7E-47 T 12-10-2018 VAPA_1c43650 e5367090c0fa647c0dbc34ea136be795 109 Pfam PF00462 Glutaredoxin 18 84 2.0E-17 T 12-10-2018 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 VAPA_1c43650 e5367090c0fa647c0dbc34ea136be795 109 PIRSF PIRSF005894 1 108 1.2E-45 T 12-10-2018 IPR014434 Monothiol glutaredoxin GO:0015036 Reactome: R-HSA-1362409 VAPA_1c43650 e5367090c0fa647c0dbc34ea136be795 109 SUPERFAMILY SSF52833 1 105 1.55E-32 T 12-10-2018 IPR036249 Thioredoxin-like superfamily VAPA_1c43650 e5367090c0fa647c0dbc34ea136be795 109 Gene3D G3DSA:3.40.30.10 7 104 3.1E-32 T 12-10-2018 VAPA_1c43650 e5367090c0fa647c0dbc34ea136be795 109 TIGRFAM TIGR00365 TIGR00365: monothiol glutaredoxin, Grx4 family 5 103 2.7E-44 T 12-10-2018 IPR004480 Monothiol glutaredoxin-related VAPA_1c19330 ad27d8ab1b752cdc322a3f902df22caf 394 SUPERFAMILY SSF53901 272 393 5.35E-44 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 VAPA_1c19330 ad27d8ab1b752cdc322a3f902df22caf 394 ProSitePatterns PS00099 Thiolases active site. 375 388 - T 12-10-2018 IPR020610 Thiolase, active site GO:0016747 VAPA_1c19330 ad27d8ab1b752cdc322a3f902df22caf 394 Gene3D G3DSA:3.40.47.10 8 277 8.2E-151 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 VAPA_1c19330 ad27d8ab1b752cdc322a3f902df22caf 394 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 87 105 - T 12-10-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0016747 VAPA_1c19330 ad27d8ab1b752cdc322a3f902df22caf 394 Pfam PF02803 Thiolase, C-terminal domain 271 393 4.2E-44 T 12-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 VAPA_1c19330 ad27d8ab1b752cdc322a3f902df22caf 394 Pfam PF00108 Thiolase, N-terminal domain 6 262 8.7E-89 T 12-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 VAPA_1c19330 ad27d8ab1b752cdc322a3f902df22caf 394 Gene3D G3DSA:3.40.47.10 129 390 8.2E-151 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 VAPA_1c19330 ad27d8ab1b752cdc322a3f902df22caf 394 PIRSF PIRSF000429 1 394 7.4E-130 T 12-10-2018 IPR002155 Thiolase GO:0016747 VAPA_1c19330 ad27d8ab1b752cdc322a3f902df22caf 394 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 8 392 2.8E-137 T 12-10-2018 IPR002155 Thiolase GO:0016747 VAPA_1c19330 ad27d8ab1b752cdc322a3f902df22caf 394 SUPERFAMILY SSF53901 5 271 1.28E-86 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 VAPA_2c07350 c1acd14c4a42ec03c62abe9aaf2b3b15 450 SUPERFAMILY SSF56059 83 344 2.53E-70 T 12-10-2018 VAPA_2c07350 c1acd14c4a42ec03c62abe9aaf2b3b15 450 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 286 293 - T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 VAPA_2c07350 c1acd14c4a42ec03c62abe9aaf2b3b15 450 Gene3D G3DSA:3.30.1490.20 131 203 1.4E-151 T 12-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 VAPA_2c07350 c1acd14c4a42ec03c62abe9aaf2b3b15 450 SUPERFAMILY SSF51246 331 444 9.94E-44 T 12-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 VAPA_2c07350 c1acd14c4a42ec03c62abe9aaf2b3b15 450 SMART SM00878 336 441 3.0E-64 T 12-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 VAPA_2c07350 c1acd14c4a42ec03c62abe9aaf2b3b15 450 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 115 322 6.3E-79 T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 VAPA_2c07350 c1acd14c4a42ec03c62abe9aaf2b3b15 450 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 154 168 - T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 VAPA_2c07350 c1acd14c4a42ec03c62abe9aaf2b3b15 450 Pfam PF02785 Biotin carboxylase C-terminal domain 336 442 1.2E-39 T 12-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 VAPA_2c07350 c1acd14c4a42ec03c62abe9aaf2b3b15 450 Gene3D G3DSA:3.30.470.20 87 433 1.4E-151 T 12-10-2018 VAPA_2c07350 c1acd14c4a42ec03c62abe9aaf2b3b15 450 Gene3D G3DSA:3.40.50.20 1 85 7.6E-29 T 12-10-2018 VAPA_2c07350 c1acd14c4a42ec03c62abe9aaf2b3b15 450 TIGRFAM TIGR00514 accC: acetyl-CoA carboxylase, biotin carboxylase subunit 1 445 1.8E-201 T 12-10-2018 IPR004549 Acetyl-CoA carboxylase, biotin carboxylase GO:0016874 VAPA_2c07350 c1acd14c4a42ec03c62abe9aaf2b3b15 450 Pfam PF00289 Biotin carboxylase, N-terminal domain 1 109 1.3E-39 T 12-10-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 VAPA_2c07350 c1acd14c4a42ec03c62abe9aaf2b3b15 450 SUPERFAMILY SSF52440 1 113 6.19E-42 T 12-10-2018 IPR016185 Pre-ATP-grasp domain superfamily VAPA_1c00900 0d6e74bc869808a6c7cf5c52c2558066 267 PRINTS PR00111 Alpha/beta hydrolase fold signature 123 136 5.8E-6 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 VAPA_1c00900 0d6e74bc869808a6c7cf5c52c2558066 267 PRINTS PR00111 Alpha/beta hydrolase fold signature 57 72 5.8E-6 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 VAPA_1c00900 0d6e74bc869808a6c7cf5c52c2558066 267 PRINTS PR00111 Alpha/beta hydrolase fold signature 109 122 5.8E-6 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 VAPA_1c00900 0d6e74bc869808a6c7cf5c52c2558066 267 Pfam PF12697 Alpha/beta hydrolase family 32 252 3.4E-16 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 VAPA_1c00900 0d6e74bc869808a6c7cf5c52c2558066 267 Gene3D G3DSA:3.40.50.1820 7 264 1.2E-42 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c00900 0d6e74bc869808a6c7cf5c52c2558066 267 SUPERFAMILY SSF53474 15 259 6.16E-47 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c15940 7dc75a24c5e7b4d822b0d3993c96b6bf 441 Pfam PF00355 Rieske [2Fe-2S] domain 42 126 6.5E-18 T 12-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 VAPA_1c15940 7dc75a24c5e7b4d822b0d3993c96b6bf 441 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 57 72 3.4E-27 T 12-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 VAPA_1c15940 7dc75a24c5e7b4d822b0d3993c96b6bf 441 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 78 98 3.4E-27 T 12-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 VAPA_1c15940 7dc75a24c5e7b4d822b0d3993c96b6bf 441 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 188 210 3.4E-27 T 12-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 VAPA_1c15940 7dc75a24c5e7b4d822b0d3993c96b6bf 441 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 27 52 3.4E-27 T 12-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 VAPA_1c15940 7dc75a24c5e7b4d822b0d3993c96b6bf 441 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 100 120 3.4E-27 T 12-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 VAPA_1c15940 7dc75a24c5e7b4d822b0d3993c96b6bf 441 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 146 172 3.4E-27 T 12-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 VAPA_1c15940 7dc75a24c5e7b4d822b0d3993c96b6bf 441 Gene3D G3DSA:3.90.380.10 19 433 6.3E-92 T 12-10-2018 VAPA_1c15940 7dc75a24c5e7b4d822b0d3993c96b6bf 441 SUPERFAMILY SSF50022 8 159 9.95E-43 T 12-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 VAPA_1c15940 7dc75a24c5e7b4d822b0d3993c96b6bf 441 Pfam PF00848 Ring hydroxylating alpha subunit (catalytic domain) 200 393 1.0E-12 T 12-10-2018 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0044237|GO:0051537|GO:0055114 VAPA_1c15940 7dc75a24c5e7b4d822b0d3993c96b6bf 441 SUPERFAMILY SSF55961 163 438 6.91E-50 T 12-10-2018 VAPA_1c15940 7dc75a24c5e7b4d822b0d3993c96b6bf 441 Gene3D G3DSA:2.102.10.10 40 171 6.3E-92 T 12-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 VAPA_1c20410 e7a301081f325a97deedb45e6b66118d 421 Gene3D G3DSA:3.90.380.10 22 419 5.7E-87 T 12-10-2018 VAPA_1c20410 e7a301081f325a97deedb45e6b66118d 421 Gene3D G3DSA:2.102.10.10 45 180 5.7E-87 T 12-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 VAPA_1c20410 e7a301081f325a97deedb45e6b66118d 421 SUPERFAMILY SSF55961 181 419 2.35E-53 T 12-10-2018 VAPA_1c20410 e7a301081f325a97deedb45e6b66118d 421 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 60 75 1.6E-27 T 12-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 VAPA_1c20410 e7a301081f325a97deedb45e6b66118d 421 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 156 182 1.6E-27 T 12-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 VAPA_1c20410 e7a301081f325a97deedb45e6b66118d 421 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 81 101 1.6E-27 T 12-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 VAPA_1c20410 e7a301081f325a97deedb45e6b66118d 421 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 195 217 1.6E-27 T 12-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 VAPA_1c20410 e7a301081f325a97deedb45e6b66118d 421 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 104 124 1.6E-27 T 12-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 VAPA_1c20410 e7a301081f325a97deedb45e6b66118d 421 Pfam PF00848 Ring hydroxylating alpha subunit (catalytic domain) 206 420 3.6E-20 T 12-10-2018 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0044237|GO:0051537|GO:0055114 VAPA_1c20410 e7a301081f325a97deedb45e6b66118d 421 SUPERFAMILY SSF50022 13 172 1.26E-39 T 12-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 VAPA_1c20410 e7a301081f325a97deedb45e6b66118d 421 Pfam PF00355 Rieske [2Fe-2S] domain 45 133 1.2E-16 T 12-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 VAPA_1c07040 e7a301081f325a97deedb45e6b66118d 421 Gene3D G3DSA:3.90.380.10 22 419 5.7E-87 T 12-10-2018 VAPA_1c07040 e7a301081f325a97deedb45e6b66118d 421 Gene3D G3DSA:2.102.10.10 45 180 5.7E-87 T 12-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 VAPA_1c07040 e7a301081f325a97deedb45e6b66118d 421 SUPERFAMILY SSF55961 181 419 2.35E-53 T 12-10-2018 VAPA_1c07040 e7a301081f325a97deedb45e6b66118d 421 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 60 75 1.6E-27 T 12-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 VAPA_1c07040 e7a301081f325a97deedb45e6b66118d 421 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 156 182 1.6E-27 T 12-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 VAPA_1c07040 e7a301081f325a97deedb45e6b66118d 421 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 81 101 1.6E-27 T 12-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 VAPA_1c07040 e7a301081f325a97deedb45e6b66118d 421 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 195 217 1.6E-27 T 12-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 VAPA_1c07040 e7a301081f325a97deedb45e6b66118d 421 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 104 124 1.6E-27 T 12-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 VAPA_1c07040 e7a301081f325a97deedb45e6b66118d 421 Pfam PF00848 Ring hydroxylating alpha subunit (catalytic domain) 206 420 3.6E-20 T 12-10-2018 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0044237|GO:0051537|GO:0055114 VAPA_1c07040 e7a301081f325a97deedb45e6b66118d 421 SUPERFAMILY SSF50022 13 172 1.26E-39 T 12-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 VAPA_1c07040 e7a301081f325a97deedb45e6b66118d 421 Pfam PF00355 Rieske [2Fe-2S] domain 45 133 1.2E-16 T 12-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 VAPA_1c12140 4aa8d64f9cb872435e0b26f9e9687677 260 TIGRFAM TIGR00056 TIGR00056: ABC transport permease subunit 31 258 2.1E-78 T 12-10-2018 IPR003453 ABC transport permease subunit MlaE, Proteobacteria VAPA_1c12140 4aa8d64f9cb872435e0b26f9e9687677 260 Pfam PF02405 Permease MlaE 46 255 2.7E-71 T 12-10-2018 IPR030802 ABC transporter permease MalE GO:0043190 VAPA_1c21620 1af5a8a04bff946bd74d3f380ff06c4f 323 SUPERFAMILY SSF53850 111 284 2.35E-7 T 12-10-2018 VAPA_1c21620 1af5a8a04bff946bd74d3f380ff06c4f 323 PIRSF PIRSF017082 1 322 1.3E-65 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c21620 1af5a8a04bff946bd74d3f380ff06c4f 323 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 45 319 6.8E-77 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c21620 1af5a8a04bff946bd74d3f380ff06c4f 323 Gene3D G3DSA:3.40.190.150 26 312 7.1E-98 T 12-10-2018 VAPA_1c21620 1af5a8a04bff946bd74d3f380ff06c4f 323 Gene3D G3DSA:3.40.190.10 124 247 7.1E-98 T 12-10-2018 VAPA_2c02690 88e01db245d5b943b48d76408f0aed4c 471 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 14 36 9.8E-7 T 12-10-2018 VAPA_2c02690 88e01db245d5b943b48d76408f0aed4c 471 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 309 316 9.8E-7 T 12-10-2018 VAPA_2c02690 88e01db245d5b943b48d76408f0aed4c 471 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 161 186 9.8E-7 T 12-10-2018 VAPA_2c02690 88e01db245d5b943b48d76408f0aed4c 471 Gene3D G3DSA:3.50.50.60 129 270 2.2E-33 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_2c02690 88e01db245d5b943b48d76408f0aed4c 471 PIRSF PIRSF037495 7 471 5.1E-137 T 12-10-2018 IPR017224 Opine oxidase, subunit A/hydrogen cyanide synthase, subunit B GO:0016491|GO:0055114 VAPA_2c02690 88e01db245d5b943b48d76408f0aed4c 471 Pfam PF04324 BFD-like [2Fe-2S] binding domain 388 440 1.5E-9 T 12-10-2018 IPR007419 BFD-like [2Fe-2S]-binding domain VAPA_2c02690 88e01db245d5b943b48d76408f0aed4c 471 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 15 34 1.2E-10 T 12-10-2018 VAPA_2c02690 88e01db245d5b943b48d76408f0aed4c 471 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 294 316 1.2E-10 T 12-10-2018 VAPA_2c02690 88e01db245d5b943b48d76408f0aed4c 471 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 117 135 1.2E-10 T 12-10-2018 VAPA_2c02690 88e01db245d5b943b48d76408f0aed4c 471 Gene3D G3DSA:3.50.50.60 15 328 2.2E-33 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_2c02690 88e01db245d5b943b48d76408f0aed4c 471 Gene3D G3DSA:1.10.10.1100 377 450 8.4E-19 T 12-10-2018 VAPA_2c02690 88e01db245d5b943b48d76408f0aed4c 471 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 14 317 2.2E-18 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 VAPA_2c02690 88e01db245d5b943b48d76408f0aed4c 471 SUPERFAMILY SSF51905 9 338 1.46E-34 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_2c05980 46eac6c8bf405947acf829983cefa52c 181 Pfam PF14066 Protein of unknown function (DUF4256) 9 180 2.8E-88 T 12-10-2018 IPR025352 Protein of unknown function DUF4256 VAPA_1c33490 57c16ecbba290ec0d69081702a558ded 158 SUPERFAMILY SSF55811 5 137 1.31E-24 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 VAPA_1c33490 57c16ecbba290ec0d69081702a558ded 158 Pfam PF00293 NUDIX domain 13 129 3.7E-15 T 12-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 VAPA_1c33490 57c16ecbba290ec0d69081702a558ded 158 Gene3D G3DSA:3.90.79.10 1 151 3.3E-36 T 12-10-2018 VAPA_1c33490 57c16ecbba290ec0d69081702a558ded 158 PRINTS PR00502 NUDIX hydrolase family signature 50 65 1.9E-5 T 12-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 VAPA_1c33490 57c16ecbba290ec0d69081702a558ded 158 PRINTS PR00502 NUDIX hydrolase family signature 36 50 1.9E-5 T 12-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 VAPA_1c33490 57c16ecbba290ec0d69081702a558ded 158 ProSitePatterns PS00893 Nudix box signature. 41 62 - T 12-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 VAPA_1c30180 66d1a09b9dfd8384ef2a3730ef778227 273 ProSitePatterns PS01311 Prolipoprotein diacylglyceryl transferase signature. 145 157 - T 12-10-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0016020|GO:0016757|GO:0042158 VAPA_1c30180 66d1a09b9dfd8384ef2a3730ef778227 273 TIGRFAM TIGR00544 lgt: prolipoprotein diacylglyceryl transferase 3 268 1.5E-79 T 12-10-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0016020|GO:0016757|GO:0042158 VAPA_1c30180 66d1a09b9dfd8384ef2a3730ef778227 273 Hamap MF_01147 Prolipoprotein diacylglyceryl transferase [lgt]. 6 268 19.344 T 12-10-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0016020|GO:0016757|GO:0042158 VAPA_1c30180 66d1a09b9dfd8384ef2a3730ef778227 273 Pfam PF01790 Prolipoprotein diacylglyceryl transferase 9 263 1.3E-78 T 12-10-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0016020|GO:0016757|GO:0042158 VAPA_1c11860 fb73fedebee34a5c440d7a91ed24ae06 393 ProSitePatterns PS00376 S-adenosylmethionine synthase signature 1. 119 129 - T 12-10-2018 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 VAPA_1c11860 fb73fedebee34a5c440d7a91ed24ae06 393 Gene3D G3DSA:3.30.300.10 6 241 1.8E-173 T 12-10-2018 VAPA_1c11860 fb73fedebee34a5c440d7a91ed24ae06 393 Pfam PF02772 S-adenosylmethionine synthetase, central domain 118 239 7.0E-45 T 12-10-2018 IPR022629 S-adenosylmethionine synthetase, central domain GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 VAPA_1c11860 fb73fedebee34a5c440d7a91ed24ae06 393 Hamap MF_00086 S-adenosylmethionine synthase [metK]. 3 391 55.61 T 12-10-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 VAPA_1c11860 fb73fedebee34a5c440d7a91ed24ae06 393 ProSitePatterns PS00377 S-adenosylmethionine synthase signature 2. 267 275 - T 12-10-2018 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 VAPA_1c11860 fb73fedebee34a5c440d7a91ed24ae06 393 Pfam PF00438 S-adenosylmethionine synthetase, N-terminal domain 5 101 3.1E-40 T 12-10-2018 IPR022628 S-adenosylmethionine synthetase, N-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 VAPA_1c11860 fb73fedebee34a5c440d7a91ed24ae06 393 SUPERFAMILY SSF55973 113 240 2.0E-47 T 12-10-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 VAPA_1c11860 fb73fedebee34a5c440d7a91ed24ae06 393 Pfam PF02773 S-adenosylmethionine synthetase, C-terminal domain 241 379 5.5E-68 T 12-10-2018 IPR022630 S-adenosylmethionine synthetase, C-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 VAPA_1c11860 fb73fedebee34a5c440d7a91ed24ae06 393 PIRSF PIRSF000497 1 392 2.7E-167 T 12-10-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 VAPA_1c11860 fb73fedebee34a5c440d7a91ed24ae06 393 Gene3D G3DSA:3.30.300.10 12 278 1.8E-173 T 12-10-2018 VAPA_1c11860 fb73fedebee34a5c440d7a91ed24ae06 393 SUPERFAMILY SSF55973 4 110 3.45E-45 T 12-10-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 VAPA_1c11860 fb73fedebee34a5c440d7a91ed24ae06 393 SUPERFAMILY SSF55973 241 391 6.67E-67 T 12-10-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 VAPA_1c11860 fb73fedebee34a5c440d7a91ed24ae06 393 Gene3D G3DSA:3.30.300.10 103 381 1.8E-173 T 12-10-2018 VAPA_1c11860 fb73fedebee34a5c440d7a91ed24ae06 393 TIGRFAM TIGR01034 metK: methionine adenosyltransferase 6 390 9.5E-178 T 12-10-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 VAPA_1c33320 ca0a25a8902eb496ad0f36de3e415573 206 Pfam PF03006 Haemolysin-III related 4 198 4.8E-40 T 12-10-2018 IPR004254 AdipoR/Haemolysin-III-related GO:0016021 VAPA_1c33320 ca0a25a8902eb496ad0f36de3e415573 206 TIGRFAM TIGR01065 hlyIII: channel protein, hemolysin III family 5 201 1.4E-54 T 12-10-2018 IPR005744 Hly-III GO:0016021|GO:0019835 VAPA_1c27260 1a01b41ef20d1aabe449bcd1821c937c 783 ProSitePatterns PS60002 Phosphoketolase signature 1. 138 144 - T 12-10-2018 IPR019790 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, conserved site GO:0005975|GO:0016832 VAPA_1c27260 1a01b41ef20d1aabe449bcd1821c937c 783 SUPERFAMILY SSF52518 4 363 5.6E-72 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold VAPA_1c27260 1a01b41ef20d1aabe449bcd1821c937c 783 Pfam PF03894 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase 393 569 1.4E-87 T 12-10-2018 IPR005593 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase GO:0005975|GO:0016832 VAPA_1c27260 1a01b41ef20d1aabe449bcd1821c937c 783 Gene3D G3DSA:3.40.50.970 381 599 3.9E-102 T 12-10-2018 VAPA_1c27260 1a01b41ef20d1aabe449bcd1821c937c 783 Pfam PF09363 XFP C-terminal domain 580 781 4.7E-91 T 12-10-2018 IPR018969 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, C-terminal GO:0005975|GO:0016832 VAPA_1c27260 1a01b41ef20d1aabe449bcd1821c937c 783 PIRSF PIRSF017245 1 783 0.0 T 12-10-2018 IPR005593 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase GO:0005975|GO:0016832 VAPA_1c27260 1a01b41ef20d1aabe449bcd1821c937c 783 SUPERFAMILY SSF52518 370 586 3.53E-26 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold VAPA_1c27260 1a01b41ef20d1aabe449bcd1821c937c 783 ProSitePatterns PS60003 Phosphoketolase signature 2. 151 169 - T 12-10-2018 IPR019789 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, thiamine diphosphate binding site GO:0005975|GO:0016832 VAPA_1c27260 1a01b41ef20d1aabe449bcd1821c937c 783 Pfam PF09364 XFP N-terminal domain 7 378 7.3E-183 T 12-10-2018 IPR018970 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, N-terminal VAPA_1c27260 1a01b41ef20d1aabe449bcd1821c937c 783 Gene3D G3DSA:3.40.50.920 600 783 7.4E-78 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 VAPA_1c27260 1a01b41ef20d1aabe449bcd1821c937c 783 Hamap MF_01403 Probable phosphoketolase. 1 783 40.068 T 12-10-2018 IPR023962 Probable phosphoketolase VAPA_1c27260 1a01b41ef20d1aabe449bcd1821c937c 783 Gene3D G3DSA:3.40.50.970 1 380 1.6E-173 T 12-10-2018 VAPA_1c38710 97589ca5ec824e065a5763db05ac5ec6 1771 Pfam PF00501 AMP-binding enzyme 43 467 2.3E-81 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 VAPA_1c38710 97589ca5ec824e065a5763db05ac5ec6 1771 Pfam PF00501 AMP-binding enzyme 1163 1560 2.8E-106 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 VAPA_1c38710 97589ca5ec824e065a5763db05ac5ec6 1771 Gene3D G3DSA:3.40.50.12780 1151 1552 2.7E-150 T 12-10-2018 VAPA_1c38710 97589ca5ec824e065a5763db05ac5ec6 1771 Gene3D G3DSA:1.10.1200.10 590 675 7.7E-18 T 12-10-2018 IPR036736 ACP-like superfamily VAPA_1c38710 97589ca5ec824e065a5763db05ac5ec6 1771 Gene3D G3DSA:1.10.1200.10 1659 1738 9.1E-24 T 12-10-2018 IPR036736 ACP-like superfamily VAPA_1c38710 97589ca5ec824e065a5763db05ac5ec6 1771 Pfam PF13193 AMP-binding enzyme C-terminal domain 1568 1642 1.4E-14 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain VAPA_1c38710 97589ca5ec824e065a5763db05ac5ec6 1771 Gene3D G3DSA:3.40.50.12780 18 459 2.4E-144 T 12-10-2018 VAPA_1c38710 97589ca5ec824e065a5763db05ac5ec6 1771 SUPERFAMILY SSF56801 1121 1680 4.71E-169 T 12-10-2018 VAPA_1c38710 97589ca5ec824e065a5763db05ac5ec6 1771 Gene3D G3DSA:3.30.300.30 461 586 8.2E-33 T 12-10-2018 VAPA_1c38710 97589ca5ec824e065a5763db05ac5ec6 1771 ProSitePatterns PS00455 Putative AMP-binding domain signature. 182 193 - T 12-10-2018 IPR020845 AMP-binding, conserved site VAPA_1c38710 97589ca5ec824e065a5763db05ac5ec6 1771 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1184 1584 2.0E-139 T 12-10-2018 IPR010071 Amino acid adenylation domain VAPA_1c38710 97589ca5ec824e065a5763db05ac5ec6 1771 SUPERFAMILY SSF47336 595 710 6.41E-14 T 12-10-2018 IPR036736 ACP-like superfamily VAPA_1c38710 97589ca5ec824e065a5763db05ac5ec6 1771 SUPERFAMILY SSF56801 14 609 9.55E-108 T 12-10-2018 VAPA_1c38710 97589ca5ec824e065a5763db05ac5ec6 1771 SUPERFAMILY SSF52777 699 876 1.78E-47 T 12-10-2018 VAPA_1c38710 97589ca5ec824e065a5763db05ac5ec6 1771 SUPERFAMILY SSF47336 1659 1733 2.75E-18 T 12-10-2018 IPR036736 ACP-like superfamily VAPA_1c38710 97589ca5ec824e065a5763db05ac5ec6 1771 SUPERFAMILY SSF52777 883 1126 2.89E-57 T 12-10-2018 VAPA_1c38710 97589ca5ec824e065a5763db05ac5ec6 1771 Pfam PF00550 Phosphopantetheine attachment site 604 668 4.3E-7 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain VAPA_1c38710 97589ca5ec824e065a5763db05ac5ec6 1771 Pfam PF00550 Phosphopantetheine attachment site 1669 1732 1.4E-13 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain VAPA_1c38710 97589ca5ec824e065a5763db05ac5ec6 1771 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1303 1314 - T 12-10-2018 IPR020845 AMP-binding, conserved site VAPA_1c38710 97589ca5ec824e065a5763db05ac5ec6 1771 Gene3D G3DSA:3.30.559.30 880 1128 3.4E-141 T 12-10-2018 VAPA_1c38710 97589ca5ec824e065a5763db05ac5ec6 1771 Gene3D G3DSA:3.30.300.30 1554 1658 1.7E-36 T 12-10-2018 VAPA_1c38710 97589ca5ec824e065a5763db05ac5ec6 1771 Gene3D G3DSA:3.30.559.10 698 1071 3.4E-141 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 VAPA_1c38710 97589ca5ec824e065a5763db05ac5ec6 1771 Pfam PF00668 Condensation domain 697 1142 4.7E-103 T 12-10-2018 IPR001242 Condensation domain VAPA_1c38710 97589ca5ec824e065a5763db05ac5ec6 1771 SMART SM00823 Phosphopantetheine attachment site 1667 1736 0.0022 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 VAPA_1c38710 97589ca5ec824e065a5763db05ac5ec6 1771 SMART SM00823 Phosphopantetheine attachment site 602 674 0.033 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 VAPA_1c10750 7c6980112e14c5472b21e2ea54e89b06 92 Pfam PF01541 GIY-YIG catalytic domain 13 79 8.2E-8 T 12-10-2018 IPR000305 GIY-YIG endonuclease VAPA_1c10750 7c6980112e14c5472b21e2ea54e89b06 92 SUPERFAMILY SSF82771 12 83 1.06E-11 T 12-10-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 VAPA_1c10750 7c6980112e14c5472b21e2ea54e89b06 92 Gene3D G3DSA:3.40.1440.10 8 92 3.2E-23 T 12-10-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 VAPA_1c17680 ef58787689b46d8682338605f5a7fa7c 436 SUPERFAMILY SSF53383 8 429 1.71E-120 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase VAPA_1c17680 ef58787689b46d8682338605f5a7fa7c 436 Gene3D G3DSA:3.40.640.10 8 290 1.7E-95 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 VAPA_1c17680 ef58787689b46d8682338605f5a7fa7c 436 Gene3D G3DSA:3.90.1150.10 294 436 1.5E-48 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 VAPA_1c17680 ef58787689b46d8682338605f5a7fa7c 436 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 202 216 - T 12-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 VAPA_1c17680 ef58787689b46d8682338605f5a7fa7c 436 PIRSF PIRSF001434 3 432 1.3E-132 T 12-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 VAPA_1c17680 ef58787689b46d8682338605f5a7fa7c 436 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 10 429 6.8E-133 T 12-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 VAPA_1c17680 ef58787689b46d8682338605f5a7fa7c 436 TIGRFAM TIGR01326 OAH_OAS_sulfhy: O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase 9 429 1.0E-171 T 12-10-2018 IPR006235 O-acetylhomoserine/O-acetylserine sulfhydrylase GO:0006520|GO:0016765 VAPA_1c15450 1082c6c905ee441ee0e429f377ad201d 402 PIRSF PIRSF000521 8 154 9.7E-9 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 VAPA_1c15450 1082c6c905ee441ee0e429f377ad201d 402 PIRSF PIRSF000521 164 395 1.2E-31 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 VAPA_1c15450 1082c6c905ee441ee0e429f377ad201d 402 SUPERFAMILY SSF53383 11 391 3.31E-120 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase VAPA_1c15450 1082c6c905ee441ee0e429f377ad201d 402 Gene3D G3DSA:3.40.640.10 55 301 8.8E-137 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 VAPA_1c15450 1082c6c905ee441ee0e429f377ad201d 402 Hamap MF_01107 Acetylornithine/succinyldiaminopimelate aminotransferase [argD]. 11 395 69.138 T 12-10-2018 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 VAPA_1c15450 1082c6c905ee441ee0e429f377ad201d 402 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 219 256 - T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 VAPA_1c15450 1082c6c905ee441ee0e429f377ad201d 402 Gene3D G3DSA:3.90.1150.10 20 382 8.8E-137 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 VAPA_1c15450 1082c6c905ee441ee0e429f377ad201d 402 Pfam PF00202 Aminotransferase class-III 18 389 6.5E-107 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 VAPA_1c15450 1082c6c905ee441ee0e429f377ad201d 402 TIGRFAM TIGR00707 argD: transaminase, acetylornithine/succinylornithine family 12 389 3.8E-140 T 12-10-2018 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 VAPA_1c10810 1ce4cf76cb2e6af9f69a5d4a4959ce2c 354 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 5 349 6.5E-83 T 12-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 VAPA_1c10810 1ce4cf76cb2e6af9f69a5d4a4959ce2c 354 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 242 261 - T 12-10-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 VAPA_1c10810 1ce4cf76cb2e6af9f69a5d4a4959ce2c 354 TIGRFAM TIGR02089 TTC: tartrate dehydrogenase 1 353 8.8E-166 T 12-10-2018 IPR011829 Tartrate dehydrogenase GO:0016616|GO:0051287|GO:0055114 KEGG: 00630+1.1.1.93|KEGG: 00650+1.1.1.83 VAPA_1c10810 1ce4cf76cb2e6af9f69a5d4a4959ce2c 354 SMART SM01329 5 349 1.2E-163 T 12-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 VAPA_1c10810 1ce4cf76cb2e6af9f69a5d4a4959ce2c 354 SUPERFAMILY SSF53659 1 353 6.91E-110 T 12-10-2018 VAPA_1c10810 1ce4cf76cb2e6af9f69a5d4a4959ce2c 354 Gene3D G3DSA:3.40.718.10 1 354 8.0E-127 T 12-10-2018 VAPA_2c05140 7304ed75d7e19a0852ee74271ddcf4f2 686 SUPERFAMILY SSF54980 391 467 3.42E-18 T 12-10-2018 IPR035647 EF-G domain III/V-like VAPA_2c05140 7304ed75d7e19a0852ee74271ddcf4f2 686 Pfam PF14492 Elongation Factor G, domain II 392 465 4.7E-20 T 12-10-2018 VAPA_2c05140 7304ed75d7e19a0852ee74271ddcf4f2 686 Gene3D G3DSA:3.40.50.300 8 270 5.3E-51 T 12-10-2018 VAPA_2c05140 7304ed75d7e19a0852ee74271ddcf4f2 686 SUPERFAMILY SSF50447 250 380 1.09E-24 T 12-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily VAPA_2c05140 7304ed75d7e19a0852ee74271ddcf4f2 686 SUPERFAMILY SSF54211 467 587 1.97E-40 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold VAPA_2c05140 7304ed75d7e19a0852ee74271ddcf4f2 686 Pfam PF03764 Elongation factor G, domain IV 467 585 7.0E-40 T 12-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 VAPA_2c05140 7304ed75d7e19a0852ee74271ddcf4f2 686 Gene3D G3DSA:3.30.70.240 592 663 2.8E-77 T 12-10-2018 VAPA_2c05140 7304ed75d7e19a0852ee74271ddcf4f2 686 SMART SM00889 468 586 1.1E-57 T 12-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 VAPA_2c05140 7304ed75d7e19a0852ee74271ddcf4f2 686 SUPERFAMILY SSF54980 588 682 1.58E-20 T 12-10-2018 IPR035647 EF-G domain III/V-like VAPA_2c05140 7304ed75d7e19a0852ee74271ddcf4f2 686 SUPERFAMILY SSF52540 12 266 1.21E-60 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_2c05140 7304ed75d7e19a0852ee74271ddcf4f2 686 Pfam PF00679 Elongation factor G C-terminus 589 675 2.6E-22 T 12-10-2018 IPR000640 Elongation factor EFG, domain V-like VAPA_2c05140 7304ed75d7e19a0852ee74271ddcf4f2 686 Gene3D G3DSA:2.40.30.10 276 399 8.8E-27 T 12-10-2018 VAPA_2c05140 7304ed75d7e19a0852ee74271ddcf4f2 686 Gene3D G3DSA:3.30.70.870 400 471 1.4E-20 T 12-10-2018 VAPA_2c05140 7304ed75d7e19a0852ee74271ddcf4f2 686 Pfam PF00009 Elongation factor Tu GTP binding domain 14 265 3.9E-30 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 VAPA_2c05140 7304ed75d7e19a0852ee74271ddcf4f2 686 SMART SM00838 588 676 6.7E-20 T 12-10-2018 IPR000640 Elongation factor EFG, domain V-like VAPA_2c05140 7304ed75d7e19a0852ee74271ddcf4f2 686 Gene3D G3DSA:3.30.230.10 472 675 2.8E-77 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup VAPA_1c23000 075a4a7a01cceb7c6f468ba9d1c77f73 342 Pfam PF06968 Biotin and Thiamin Synthesis associated domain 238 328 3.5E-18 T 12-10-2018 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 VAPA_1c23000 075a4a7a01cceb7c6f468ba9d1c77f73 342 SUPERFAMILY SSF102114 24 330 4.45E-88 T 12-10-2018 VAPA_1c23000 075a4a7a01cceb7c6f468ba9d1c77f73 342 Hamap MF_01694 Biotin synthase [bioB]. 23 331 40.916 T 12-10-2018 IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB GO:0004076|GO:0009102 KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 VAPA_1c23000 075a4a7a01cceb7c6f468ba9d1c77f73 342 PIRSF PIRSF001619 6 337 1.6E-127 T 12-10-2018 IPR024177 Biotin synthase KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 VAPA_1c23000 075a4a7a01cceb7c6f468ba9d1c77f73 342 SMART SM00876 238 330 1.8E-44 T 12-10-2018 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 VAPA_1c23000 075a4a7a01cceb7c6f468ba9d1c77f73 342 Pfam PF04055 Radical SAM superfamily 67 215 4.7E-15 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 VAPA_1c23000 075a4a7a01cceb7c6f468ba9d1c77f73 342 SMART SM00729 61 273 6.2E-33 T 12-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 VAPA_1c23000 075a4a7a01cceb7c6f468ba9d1c77f73 342 TIGRFAM TIGR00433 bioB: biotin synthase 33 328 2.2E-119 T 12-10-2018 IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB GO:0004076|GO:0009102 KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 VAPA_1c23000 075a4a7a01cceb7c6f468ba9d1c77f73 342 Gene3D G3DSA:3.20.20.70 23 333 2.6E-121 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 VAPA_1c28620 aedf992813dc3328d1224d1938359346 432 SMART SM01209 101 298 4.9E-135 T 12-10-2018 VAPA_1c28620 aedf992813dc3328d1224d1938359346 432 Gene3D G3DSA:3.30.470.20 193 331 6.1E-59 T 12-10-2018 VAPA_1c28620 aedf992813dc3328d1224d1938359346 432 Pfam PF02843 Phosphoribosylglycinamide synthetase, C domain 333 422 6.0E-28 T 12-10-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 VAPA_1c28620 aedf992813dc3328d1224d1938359346 432 Pfam PF01071 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain 101 298 4.7E-77 T 12-10-2018 IPR020561 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 VAPA_1c28620 aedf992813dc3328d1224d1938359346 432 SUPERFAMILY SSF56059 102 327 2.3E-61 T 12-10-2018 VAPA_1c28620 aedf992813dc3328d1224d1938359346 432 TIGRFAM TIGR00877 purD: phosphoribosylamine--glycine ligase 1 424 6.2E-169 T 12-10-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 VAPA_1c28620 aedf992813dc3328d1224d1938359346 432 Gene3D G3DSA:3.30.1490.20 119 192 1.3E-25 T 12-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 VAPA_1c28620 aedf992813dc3328d1224d1938359346 432 SMART SM01210 332 424 3.1E-51 T 12-10-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 VAPA_1c28620 aedf992813dc3328d1224d1938359346 432 Gene3D G3DSA:3.90.600.10 332 431 2.0E-33 T 12-10-2018 IPR037123 Phosphoribosylglycinamide synthetase, C-domain superfamily GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 VAPA_1c28620 aedf992813dc3328d1224d1938359346 432 Pfam PF02844 Phosphoribosylglycinamide synthetase, N domain 1 100 7.1E-35 T 12-10-2018 IPR020562 Phosphoribosylglycinamide synthetase, N-terminal GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 VAPA_1c28620 aedf992813dc3328d1224d1938359346 432 Gene3D G3DSA:3.40.50.20 1 93 4.5E-34 T 12-10-2018 VAPA_1c28620 aedf992813dc3328d1224d1938359346 432 SUPERFAMILY SSF51246 331 424 1.26E-29 T 12-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 VAPA_1c28620 aedf992813dc3328d1224d1938359346 432 Hamap MF_00138 Phosphoribosylamine--glycine ligase [purD]. 1 424 42.271 T 12-10-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 VAPA_1c28620 aedf992813dc3328d1224d1938359346 432 SUPERFAMILY SSF52440 1 101 1.58E-33 T 12-10-2018 IPR016185 Pre-ATP-grasp domain superfamily VAPA_1c40160 33edf8cda98300da6f22b41bcca1eff3 397 Pfam PF02515 CoA-transferase family III 22 383 2.3E-115 T 12-10-2018 IPR003673 CoA-transferase family III GO:0003824 VAPA_1c40160 33edf8cda98300da6f22b41bcca1eff3 397 SUPERFAMILY SSF89796 19 389 1.7E-112 T 12-10-2018 IPR023606 CoA-transferase family III domain superfamily VAPA_1c40160 33edf8cda98300da6f22b41bcca1eff3 397 Gene3D G3DSA:3.40.50.10540 21 388 1.3E-106 T 12-10-2018 IPR023606 CoA-transferase family III domain superfamily VAPA_1c40160 33edf8cda98300da6f22b41bcca1eff3 397 Gene3D G3DSA:3.30.1540.10 244 334 1.3E-106 T 12-10-2018 VAPA_2c08430 064d882fe583cf8fda4b88216dbbdf5a 332 SUPERFAMILY SSF46689 227 277 6.48E-10 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 VAPA_2c08430 064d882fe583cf8fda4b88216dbbdf5a 332 Pfam PF12833 Helix-turn-helix domain 249 328 1.9E-22 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 VAPA_2c08430 064d882fe583cf8fda4b88216dbbdf5a 332 SMART SM00342 243 327 6.4E-24 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 VAPA_2c08430 064d882fe583cf8fda4b88216dbbdf5a 332 Pfam PF14525 AraC-binding-like domain 25 205 6.9E-40 T 12-10-2018 IPR035418 Transcription regulator HTH, AraC- type, ligand binding domain-like VAPA_2c08430 064d882fe583cf8fda4b88216dbbdf5a 332 Gene3D G3DSA:1.10.10.60 227 331 2.0E-32 T 12-10-2018 VAPA_1c15590 f5eac3e93a03a5a74027b3903de1be6b 547 SUPERFAMILY SSF81891 207 446 1.15E-38 T 12-10-2018 VAPA_1c15590 f5eac3e93a03a5a74027b3903de1be6b 547 Pfam PF01743 Poly A polymerase head domain 59 207 3.3E-31 T 12-10-2018 IPR002646 Poly A polymerase, head domain GO:0003723|GO:0006396|GO:0016779 Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 VAPA_1c15590 f5eac3e93a03a5a74027b3903de1be6b 547 Gene3D G3DSA:1.10.3090.10 206 458 8.4E-73 T 12-10-2018 VAPA_1c15590 f5eac3e93a03a5a74027b3903de1be6b 547 Pfam PF12626 Polymerase A arginine-rich C-terminus 357 469 1.2E-34 T 12-10-2018 IPR025866 Polymerase A arginine-rich C-terminal domain VAPA_1c15590 f5eac3e93a03a5a74027b3903de1be6b 547 Pfam PF12627 Probable RNA and SrmB- binding site of polymerase A 238 298 8.5E-16 T 12-10-2018 IPR032828 tRNA nucleotidyltransferase/poly(A) polymerase, RNA and SrmB- binding domain Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 VAPA_1c15590 f5eac3e93a03a5a74027b3903de1be6b 547 Hamap MF_00957 Poly(A) polymerase I [pcnB]. 18 527 33.669 T 12-10-2018 IPR010206 Poly(A) polymerase I GO:0003723|GO:0004652|GO:0006378 VAPA_1c15590 f5eac3e93a03a5a74027b3903de1be6b 547 Gene3D G3DSA:3.30.460.10 26 204 3.3E-54 T 12-10-2018 VAPA_1c15590 f5eac3e93a03a5a74027b3903de1be6b 547 SUPERFAMILY SSF81301 34 203 7.41E-36 T 12-10-2018 VAPA_1c15590 f5eac3e93a03a5a74027b3903de1be6b 547 TIGRFAM TIGR01942 pcnB: poly(A) polymerase 30 469 1.6E-134 T 12-10-2018 IPR010206 Poly(A) polymerase I GO:0003723|GO:0004652|GO:0006378 VAPA_1c53470 d994a75dc8a75cf02ee6348aecab1de9 678 SMART SM00388 444 515 2.2E-4 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 VAPA_1c53470 d994a75dc8a75cf02ee6348aecab1de9 678 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 302 427 7.1E-19 T 12-10-2018 IPR000014 PAS domain VAPA_1c53470 d994a75dc8a75cf02ee6348aecab1de9 678 Gene3D G3DSA:3.30.450.20 301 440 8.5E-22 T 12-10-2018 VAPA_1c53470 d994a75dc8a75cf02ee6348aecab1de9 678 SUPERFAMILY SSF47384 436 512 1.22E-7 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 VAPA_1c53470 d994a75dc8a75cf02ee6348aecab1de9 678 PRINTS PR00344 Bacterial sensor protein C-terminal signature 610 624 2.1E-15 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c53470 d994a75dc8a75cf02ee6348aecab1de9 678 PRINTS PR00344 Bacterial sensor protein C-terminal signature 628 638 2.1E-15 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c53470 d994a75dc8a75cf02ee6348aecab1de9 678 PRINTS PR00344 Bacterial sensor protein C-terminal signature 639 657 2.1E-15 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c53470 d994a75dc8a75cf02ee6348aecab1de9 678 PRINTS PR00344 Bacterial sensor protein C-terminal signature 663 676 2.1E-15 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c53470 d994a75dc8a75cf02ee6348aecab1de9 678 SUPERFAMILY SSF55785 289 420 8.38E-19 T 12-10-2018 IPR035965 PAS domain superfamily VAPA_1c53470 d994a75dc8a75cf02ee6348aecab1de9 678 SMART SM00387 557 678 2.1E-24 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase VAPA_1c53470 d994a75dc8a75cf02ee6348aecab1de9 678 SMART SM00091 302 368 5.5E-7 T 12-10-2018 IPR000014 PAS domain VAPA_1c53470 d994a75dc8a75cf02ee6348aecab1de9 678 Gene3D G3DSA:3.30.565.10 514 678 3.4E-37 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_1c53470 d994a75dc8a75cf02ee6348aecab1de9 678 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 558 677 6.9E-17 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase VAPA_1c53470 d994a75dc8a75cf02ee6348aecab1de9 678 Gene3D G3DSA:1.10.287.130 449 512 5.1E-19 T 12-10-2018 VAPA_1c53470 d994a75dc8a75cf02ee6348aecab1de9 678 Pfam PF13426 PAS domain 319 421 2.1E-11 T 12-10-2018 IPR000014 PAS domain VAPA_1c53470 d994a75dc8a75cf02ee6348aecab1de9 678 SUPERFAMILY SSF55874 508 676 3.54E-33 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_2c02100 b03f3beb42376d7afd8eee097cb3a849 143 SUPERFAMILY SSF160631 3 138 2.62E-19 T 12-10-2018 VAPA_2c02100 b03f3beb42376d7afd8eee097cb3a849 143 Gene3D G3DSA:3.40.1580.10 1 141 2.8E-18 T 12-10-2018 IPR037883 Knr4/Smi1-like domain superfamily VAPA_2c02100 b03f3beb42376d7afd8eee097cb3a849 143 Pfam PF14568 SMI1-KNR4 cell-wall 6 135 1.7E-19 T 12-10-2018 VAPA_2c02100 b03f3beb42376d7afd8eee097cb3a849 143 SMART SM00860 3 137 1.1E-10 T 12-10-2018 IPR018958 Knr4/Smi1-like domain VAPA_1c48730 ef090b1af086494d00f9e9606d10d2a4 667 SMART SM00878 340 451 3.2E-53 T 12-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 VAPA_1c48730 ef090b1af086494d00f9e9606d10d2a4 667 SUPERFAMILY SSF52440 1 113 2.45E-48 T 12-10-2018 IPR016185 Pre-ATP-grasp domain superfamily VAPA_1c48730 ef090b1af086494d00f9e9606d10d2a4 667 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 153 167 - T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 VAPA_1c48730 ef090b1af086494d00f9e9606d10d2a4 667 Gene3D G3DSA:2.40.50.100 586 663 9.4E-24 T 12-10-2018 VAPA_1c48730 ef090b1af086494d00f9e9606d10d2a4 667 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 116 327 3.3E-76 T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 VAPA_1c48730 ef090b1af086494d00f9e9606d10d2a4 667 Pfam PF00364 Biotin-requiring enzyme 597 661 2.5E-17 T 12-10-2018 IPR000089 Biotin/lipoyl attachment VAPA_1c48730 ef090b1af086494d00f9e9606d10d2a4 667 SUPERFAMILY SSF51230 590 661 1.83E-20 T 12-10-2018 IPR011053 Single hybrid motif VAPA_1c48730 ef090b1af086494d00f9e9606d10d2a4 667 SUPERFAMILY SSF56059 83 352 1.01E-65 T 12-10-2018 VAPA_1c48730 ef090b1af086494d00f9e9606d10d2a4 667 Pfam PF02785 Biotin carboxylase C-terminal domain 340 452 3.4E-38 T 12-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 VAPA_1c48730 ef090b1af086494d00f9e9606d10d2a4 667 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 290 297 - T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 VAPA_1c48730 ef090b1af086494d00f9e9606d10d2a4 667 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 619 636 - T 12-10-2018 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 VAPA_1c48730 ef090b1af086494d00f9e9606d10d2a4 667 Gene3D G3DSA:3.30.470.130 1 458 2.7E-202 T 12-10-2018 VAPA_1c48730 ef090b1af086494d00f9e9606d10d2a4 667 Pfam PF00289 Biotin carboxylase, N-terminal domain 1 110 1.6E-44 T 12-10-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 VAPA_1c48730 ef090b1af086494d00f9e9606d10d2a4 667 SUPERFAMILY SSF51246 335 455 4.13E-38 T 12-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 VAPA_1c53060 4bb6c103964872baf0eaedb3e7f90280 382 TIGRFAM TIGR00732 dprA: DNA protecting protein DprA 84 302 9.7E-71 T 12-10-2018 IPR003488 DNA recombination-mediator protein A GO:0009294 VAPA_1c53060 4bb6c103964872baf0eaedb3e7f90280 382 Gene3D G3DSA:1.10.10.10 306 377 1.1E-11 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c53060 4bb6c103964872baf0eaedb3e7f90280 382 SUPERFAMILY SSF102405 88 302 5.34E-41 T 12-10-2018 VAPA_1c53060 4bb6c103964872baf0eaedb3e7f90280 382 SUPERFAMILY SSF47781 3 58 2.89E-5 T 12-10-2018 IPR010994 RuvA domain 2-like VAPA_1c53060 4bb6c103964872baf0eaedb3e7f90280 382 Gene3D G3DSA:3.40.50.450 1 305 9.0E-101 T 12-10-2018 VAPA_1c53060 4bb6c103964872baf0eaedb3e7f90280 382 Pfam PF02481 DNA recombination-mediator protein A 85 293 9.8E-72 T 12-10-2018 IPR003488 DNA recombination-mediator protein A GO:0009294 VAPA_1c27670 e8c308ba840b42f07543394ae8578227 210 Pfam PF00775 Dioxygenase 44 178 1.6E-25 T 12-10-2018 IPR000627 Intradiol ring-cleavage dioxygenase, C-terminal GO:0003824|GO:0006725|GO:0008199|GO:0055114 VAPA_1c27670 e8c308ba840b42f07543394ae8578227 210 Gene3D G3DSA:2.60.130.10 19 210 2.7E-50 T 12-10-2018 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 VAPA_1c27670 e8c308ba840b42f07543394ae8578227 210 ProSitePatterns PS00083 Intradiol ring-cleavage dioxygenases signature. 76 104 - T 12-10-2018 IPR000627 Intradiol ring-cleavage dioxygenase, C-terminal GO:0003824|GO:0006725|GO:0008199|GO:0055114 VAPA_1c27670 e8c308ba840b42f07543394ae8578227 210 SUPERFAMILY SSF49482 25 192 2.09E-51 T 12-10-2018 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 VAPA_1c44960 9996d8298512bd5e62e045d805a77562 206 ProSitePatterns PS00856 Guanylate kinase-like signature. 39 56 - T 12-10-2018 IPR020590 Guanylate kinase, conserved site KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221 VAPA_1c44960 9996d8298512bd5e62e045d805a77562 206 Gene3D G3DSA:3.40.50.300 9 182 7.2E-66 T 12-10-2018 VAPA_1c44960 9996d8298512bd5e62e045d805a77562 206 Hamap MF_00328 Guanylate kinase [gmk]. 3 186 35.275 T 12-10-2018 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 VAPA_1c44960 9996d8298512bd5e62e045d805a77562 206 TIGRFAM TIGR03263 guanyl_kin: guanylate kinase 5 183 5.1E-70 T 12-10-2018 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 VAPA_1c44960 9996d8298512bd5e62e045d805a77562 206 SUPERFAMILY SSF52540 3 188 1.93E-64 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c44960 9996d8298512bd5e62e045d805a77562 206 Gene3D G3DSA:3.30.63.10 36 95 7.2E-66 T 12-10-2018 VAPA_1c44960 9996d8298512bd5e62e045d805a77562 206 Pfam PF00625 Guanylate kinase 7 184 4.9E-47 T 12-10-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit VAPA_1c44960 9996d8298512bd5e62e045d805a77562 206 SMART SM00072 4 186 6.7E-59 T 12-10-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit VAPA_1c49070 d08f48bd74bfbb81c04d7fe33fc0c48f 313 Gene3D G3DSA:1.10.10.10 10 96 2.2E-26 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c49070 d08f48bd74bfbb81c04d7fe33fc0c48f 313 SUPERFAMILY SSF46785 10 119 2.25E-23 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c49070 d08f48bd74bfbb81c04d7fe33fc0c48f 313 Gene3D G3DSA:3.40.190.290 98 298 5.3E-52 T 12-10-2018 VAPA_1c49070 d08f48bd74bfbb81c04d7fe33fc0c48f 313 Pfam PF03466 LysR substrate binding domain 95 297 1.1E-35 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_1c49070 d08f48bd74bfbb81c04d7fe33fc0c48f 313 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 37 47 5.4E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c49070 d08f48bd74bfbb81c04d7fe33fc0c48f 313 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 47 58 5.4E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c49070 d08f48bd74bfbb81c04d7fe33fc0c48f 313 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 26 37 5.4E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c49070 d08f48bd74bfbb81c04d7fe33fc0c48f 313 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 12 70 1.2E-19 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c49070 d08f48bd74bfbb81c04d7fe33fc0c48f 313 SUPERFAMILY SSF53850 95 302 7.96E-37 T 12-10-2018 VAPA_1c46520 2d5a0fc7d1fa780329d2ca7d87a8c39e 441 Gene3D G3DSA:1.20.1250.20 20 436 3.0E-54 T 12-10-2018 VAPA_1c46520 2d5a0fc7d1fa780329d2ca7d87a8c39e 441 Pfam PF07690 Major Facilitator Superfamily 42 289 2.1E-28 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 VAPA_1c46520 2d5a0fc7d1fa780329d2ca7d87a8c39e 441 Pfam PF07690 Major Facilitator Superfamily 296 436 8.2E-13 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 VAPA_1c46520 2d5a0fc7d1fa780329d2ca7d87a8c39e 441 SUPERFAMILY SSF103473 27 435 2.49E-56 T 12-10-2018 IPR036259 MFS transporter superfamily VAPA_1c46520 2d5a0fc7d1fa780329d2ca7d87a8c39e 441 TIGRFAM TIGR04259 oxa_formateAnti: oxalate/formate antiporter 33 437 1.2E-201 T 12-10-2018 IPR026355 Oxalate/formate antiporter GO:0016021|GO:0019531|GO:0019532 VAPA_1c22990 22abff7e77990a5c5f3d0f63110e05e0 690 Pfam PF00364 Biotin-requiring enzyme 625 688 2.9E-15 T 12-10-2018 IPR000089 Biotin/lipoyl attachment VAPA_1c22990 22abff7e77990a5c5f3d0f63110e05e0 690 SUPERFAMILY SSF51230 613 689 1.06E-18 T 12-10-2018 IPR011053 Single hybrid motif VAPA_1c22990 22abff7e77990a5c5f3d0f63110e05e0 690 Gene3D G3DSA:3.30.470.130 2 464 1.6E-200 T 12-10-2018 VAPA_1c22990 22abff7e77990a5c5f3d0f63110e05e0 690 Gene3D G3DSA:2.40.50.100 620 690 1.3E-18 T 12-10-2018 VAPA_1c22990 22abff7e77990a5c5f3d0f63110e05e0 690 Pfam PF02785 Biotin carboxylase C-terminal domain 344 460 4.4E-38 T 12-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 VAPA_1c22990 22abff7e77990a5c5f3d0f63110e05e0 690 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 646 663 - T 12-10-2018 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 VAPA_1c22990 22abff7e77990a5c5f3d0f63110e05e0 690 Gene3D G3DSA:3.30.700.30 467 609 7.3E-14 T 12-10-2018 VAPA_1c22990 22abff7e77990a5c5f3d0f63110e05e0 690 SMART SM00878 344 460 2.3E-62 T 12-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 VAPA_1c22990 22abff7e77990a5c5f3d0f63110e05e0 690 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 123 330 1.0E-81 T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 VAPA_1c22990 22abff7e77990a5c5f3d0f63110e05e0 690 SUPERFAMILY SSF56059 91 356 5.48E-69 T 12-10-2018 VAPA_1c22990 22abff7e77990a5c5f3d0f63110e05e0 690 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 294 301 - T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 VAPA_1c22990 22abff7e77990a5c5f3d0f63110e05e0 690 SUPERFAMILY SSF52440 5 121 1.58E-47 T 12-10-2018 IPR016185 Pre-ATP-grasp domain superfamily VAPA_1c22990 22abff7e77990a5c5f3d0f63110e05e0 690 SUPERFAMILY SSF51246 339 463 1.15E-42 T 12-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 VAPA_1c22990 22abff7e77990a5c5f3d0f63110e05e0 690 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 161 175 - T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 VAPA_1c22990 22abff7e77990a5c5f3d0f63110e05e0 690 Pfam PF00289 Biotin carboxylase, N-terminal domain 9 116 6.6E-45 T 12-10-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 VAPA_1c25770 cd6ddbd630fb8a44ffdcd66ff59e0457 389 Hamap MF_01229 Alkanesulfonate monooxygenase [ssuD]. 1 385 77.449 T 12-10-2018 IPR019911 Alkanesulphonate monooxygenase, FMN-dependent GO:0008726|GO:0055114 KEGG: 00920+1.14.14.5 VAPA_1c25770 cd6ddbd630fb8a44ffdcd66ff59e0457 389 SUPERFAMILY SSF51679 1 355 2.62E-95 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 VAPA_1c25770 cd6ddbd630fb8a44ffdcd66ff59e0457 389 TIGRFAM TIGR03565 alk_sulf_monoox: alkanesulfonate monooxygenase, FMNH(2)-dependent 2 355 1.6E-186 T 12-10-2018 IPR019911 Alkanesulphonate monooxygenase, FMN-dependent GO:0008726|GO:0055114 KEGG: 00920+1.14.14.5 VAPA_1c25770 cd6ddbd630fb8a44ffdcd66ff59e0457 389 Pfam PF00296 Luciferase-like monooxygenase 1 331 6.5E-87 T 12-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 VAPA_1c25770 cd6ddbd630fb8a44ffdcd66ff59e0457 389 Gene3D G3DSA:3.20.20.30 1 364 4.2E-144 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 VAPA_1c26670 f6209d04afcfec507f130bd42f24ded8 638 SUPERFAMILY SSF47384 218 298 5.3E-12 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 VAPA_1c26670 f6209d04afcfec507f130bd42f24ded8 638 Pfam PF06983 3-demethylubiquinone-9 3-methyltransferase 482 596 2.7E-43 T 12-10-2018 IPR028973 PhnB-like VAPA_1c26670 f6209d04afcfec507f130bd42f24ded8 638 PRINTS PR00344 Bacterial sensor protein C-terminal signature 382 396 8.5E-11 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c26670 f6209d04afcfec507f130bd42f24ded8 638 PRINTS PR00344 Bacterial sensor protein C-terminal signature 414 432 8.5E-11 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c26670 f6209d04afcfec507f130bd42f24ded8 638 PRINTS PR00344 Bacterial sensor protein C-terminal signature 400 410 8.5E-11 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c26670 f6209d04afcfec507f130bd42f24ded8 638 SUPERFAMILY SSF55874 291 451 1.27E-34 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_1c26670 f6209d04afcfec507f130bd42f24ded8 638 Pfam PF00512 His Kinase A (phospho-acceptor) domain 237 298 6.5E-11 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 VAPA_1c26670 f6209d04afcfec507f130bd42f24ded8 638 SUPERFAMILY SSF54593 483 635 3.7E-47 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase VAPA_1c26670 f6209d04afcfec507f130bd42f24ded8 638 SMART SM00388 235 300 1.2E-8 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 VAPA_1c26670 f6209d04afcfec507f130bd42f24ded8 638 Gene3D G3DSA:3.30.565.10 304 455 8.1E-34 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_1c26670 f6209d04afcfec507f130bd42f24ded8 638 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 345 451 4.8E-19 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase VAPA_1c26670 f6209d04afcfec507f130bd42f24ded8 638 Gene3D G3DSA:1.10.287.130 186 301 5.8E-16 T 12-10-2018 VAPA_1c26670 f6209d04afcfec507f130bd42f24ded8 638 SMART SM00387 344 455 7.4E-29 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase VAPA_1c26670 f6209d04afcfec507f130bd42f24ded8 638 Gene3D G3DSA:3.10.180.70 479 638 1.5E-60 T 12-10-2018 VAPA_1c08000 39edcde5f9f9df0b1244353f1e60e89c 580 SUPERFAMILY SSF54631 460 577 1.42E-15 T 12-10-2018 VAPA_1c08000 39edcde5f9f9df0b1244353f1e60e89c 580 Gene3D G3DSA:1.10.3080.10 23 444 1.4E-97 T 12-10-2018 IPR014743 Chloride channel, core Reactome: R-HSA-2672351 VAPA_1c08000 39edcde5f9f9df0b1244353f1e60e89c 580 Pfam PF00654 Voltage gated chloride channel 82 423 9.2E-84 T 12-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 VAPA_1c08000 39edcde5f9f9df0b1244353f1e60e89c 580 Pfam PF00571 CBS domain 519 573 1.1E-5 T 12-10-2018 IPR000644 CBS domain VAPA_1c08000 39edcde5f9f9df0b1244353f1e60e89c 580 Gene3D G3DSA:3.10.580.10 457 579 9.3E-14 T 12-10-2018 VAPA_1c08000 39edcde5f9f9df0b1244353f1e60e89c 580 PRINTS PR00762 Chloride channel signature 391 410 7.2E-20 T 12-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 VAPA_1c08000 39edcde5f9f9df0b1244353f1e60e89c 580 PRINTS PR00762 Chloride channel signature 175 194 7.2E-20 T 12-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 VAPA_1c08000 39edcde5f9f9df0b1244353f1e60e89c 580 PRINTS PR00762 Chloride channel signature 338 358 7.2E-20 T 12-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 VAPA_1c08000 39edcde5f9f9df0b1244353f1e60e89c 580 PRINTS PR00762 Chloride channel signature 124 143 7.2E-20 T 12-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 VAPA_1c08000 39edcde5f9f9df0b1244353f1e60e89c 580 PRINTS PR00762 Chloride channel signature 373 389 7.2E-20 T 12-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 VAPA_1c08000 39edcde5f9f9df0b1244353f1e60e89c 580 SUPERFAMILY SSF81340 11 441 1.57E-98 T 12-10-2018 IPR014743 Chloride channel, core Reactome: R-HSA-2672351 VAPA_1c08710 987e75f771d00ab81750235b56372900 598 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 44 160 6.0E-12 T 12-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 VAPA_1c08710 987e75f771d00ab81750235b56372900 598 Gene3D G3DSA:2.40.110.10 163 289 3.7E-25 T 12-10-2018 VAPA_1c08710 987e75f771d00ab81750235b56372900 598 SUPERFAMILY SSF47203 289 473 5.15E-49 T 12-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 VAPA_1c08710 987e75f771d00ab81750235b56372900 598 Pfam PF12806 Acetyl-CoA dehydrogenase C-terminal like 473 593 9.0E-27 T 12-10-2018 IPR025878 Acetyl-CoA dehydrogenase-like C-terminal domain VAPA_1c08710 987e75f771d00ab81750235b56372900 598 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 284 452 7.2E-21 T 12-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 VAPA_1c08710 987e75f771d00ab81750235b56372900 598 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 165 273 1.2E-14 T 12-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 VAPA_1c08710 987e75f771d00ab81750235b56372900 598 Gene3D G3DSA:1.10.540.10 20 162 1.4E-17 T 12-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 VAPA_1c08710 987e75f771d00ab81750235b56372900 598 Gene3D G3DSA:1.20.140.10 290 458 8.6E-45 T 12-10-2018 VAPA_1c08710 987e75f771d00ab81750235b56372900 598 Pfam PF12418 Acyl-CoA dehydrogenase N terminal 3 35 1.2E-12 T 12-10-2018 IPR020953 Acyl-CoA dehydrogenase, N-terminal, bacteria VAPA_1c08710 987e75f771d00ab81750235b56372900 598 SUPERFAMILY SSF56645 37 278 3.27E-57 T 12-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 VAPA_1c06310 cc2ae0e645c34b4f7d4e954c35817822 227 SMART SM00421 161 218 5.6E-23 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_1c06310 cc2ae0e645c34b4f7d4e954c35817822 227 Pfam PF00072 Response regulator receiver domain 3 113 4.5E-19 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_1c06310 cc2ae0e645c34b4f7d4e954c35817822 227 Pfam PF00196 Bacterial regulatory proteins, luxR family 163 217 6.5E-19 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_1c06310 cc2ae0e645c34b4f7d4e954c35817822 227 SUPERFAMILY SSF52172 1 128 9.11E-26 T 12-10-2018 IPR011006 CheY-like superfamily VAPA_1c06310 cc2ae0e645c34b4f7d4e954c35817822 227 SMART SM00448 1 113 3.9E-17 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_1c06310 cc2ae0e645c34b4f7d4e954c35817822 227 Gene3D G3DSA:1.10.10.10 154 227 9.3E-23 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c06310 cc2ae0e645c34b4f7d4e954c35817822 227 Gene3D G3DSA:3.40.50.2300 1 125 1.8E-26 T 12-10-2018 VAPA_1c06310 cc2ae0e645c34b4f7d4e954c35817822 227 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 178 194 9.5E-11 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_1c06310 cc2ae0e645c34b4f7d4e954c35817822 227 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 164 178 9.5E-11 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_1c06310 cc2ae0e645c34b4f7d4e954c35817822 227 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 194 206 9.5E-11 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_1c06310 cc2ae0e645c34b4f7d4e954c35817822 227 SUPERFAMILY SSF46894 156 220 1.84E-18 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 VAPA_1c52190 f7b5510a58d145211f201ec67f036e4c 852 PRINTS PR00369 Flavodoxin signature 443 454 4.8E-7 T 12-10-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 VAPA_1c52190 f7b5510a58d145211f201ec67f036e4c 852 PRINTS PR00369 Flavodoxin signature 395 408 4.8E-7 T 12-10-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 VAPA_1c52190 f7b5510a58d145211f201ec67f036e4c 852 PRINTS PR00369 Flavodoxin signature 475 485 4.8E-7 T 12-10-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 VAPA_1c52190 f7b5510a58d145211f201ec67f036e4c 852 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 811 819 3.4E-8 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 VAPA_1c52190 f7b5510a58d145211f201ec67f036e4c 852 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 720 739 3.4E-8 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 VAPA_1c52190 f7b5510a58d145211f201ec67f036e4c 852 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 788 804 3.4E-8 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 VAPA_1c52190 f7b5510a58d145211f201ec67f036e4c 852 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 657 664 3.4E-8 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 VAPA_1c52190 f7b5510a58d145211f201ec67f036e4c 852 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 684 693 3.4E-8 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 VAPA_1c52190 f7b5510a58d145211f201ec67f036e4c 852 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 744 753 3.4E-8 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 VAPA_1c52190 f7b5510a58d145211f201ec67f036e4c 852 Pfam PF00175 Oxidoreductase NAD-binding domain 721 825 3.0E-9 T 12-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 VAPA_1c52190 f7b5510a58d145211f201ec67f036e4c 852 Pfam PF00258 Flavodoxin 397 519 1.0E-22 T 12-10-2018 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 VAPA_1c52190 f7b5510a58d145211f201ec67f036e4c 852 Gene3D G3DSA:3.40.50.360 389 539 4.1E-35 T 12-10-2018 IPR029039 Flavoprotein-like superfamily VAPA_1c52190 f7b5510a58d145211f201ec67f036e4c 852 SUPERFAMILY SSF52343 712 852 2.23E-31 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain VAPA_1c52190 f7b5510a58d145211f201ec67f036e4c 852 Pfam PF03929 PepSY-associated TM region 9 366 8.5E-57 T 12-10-2018 IPR005625 PepSY-associated TM protein VAPA_1c52190 f7b5510a58d145211f201ec67f036e4c 852 SUPERFAMILY SSF63380 555 710 1.05E-17 T 12-10-2018 IPR017938 Riboflavin synthase-like beta-barrel VAPA_1c52190 f7b5510a58d145211f201ec67f036e4c 852 Gene3D G3DSA:3.40.50.80 711 852 1.1E-32 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain VAPA_1c52190 f7b5510a58d145211f201ec67f036e4c 852 SUPERFAMILY SSF52218 393 537 2.51E-35 T 12-10-2018 IPR029039 Flavoprotein-like superfamily VAPA_1c32210 3d2fd4dc0bd9a1dc963e66ba5fed6a63 277 Gene3D G3DSA:1.10.10.10 1 78 1.0E-25 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c32210 3d2fd4dc0bd9a1dc963e66ba5fed6a63 277 Pfam PF01380 SIS domain 123 250 1.9E-19 T 12-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 VAPA_1c32210 3d2fd4dc0bd9a1dc963e66ba5fed6a63 277 SUPERFAMILY SSF53697 92 274 1.96E-40 T 12-10-2018 VAPA_1c32210 3d2fd4dc0bd9a1dc963e66ba5fed6a63 277 SUPERFAMILY SSF46689 2 76 2.87E-16 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 VAPA_1c32210 3d2fd4dc0bd9a1dc963e66ba5fed6a63 277 Pfam PF01418 Helix-turn-helix domain, rpiR family 2 72 6.9E-17 T 12-10-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 VAPA_1c32210 3d2fd4dc0bd9a1dc963e66ba5fed6a63 277 Gene3D G3DSA:3.40.50.10490 90 273 9.9E-47 T 12-10-2018 VAPA_1c31760 6679341a6fbf9954f7fabc361dc9c2b1 365 SUPERFAMILY SSF53927 1 140 2.01E-41 T 12-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 VAPA_1c31760 6679341a6fbf9954f7fabc361dc9c2b1 365 TIGRFAM TIGR00326 eubact_ribD: riboflavin biosynthesis protein RibD 1 354 2.3E-104 T 12-10-2018 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-7991 VAPA_1c31760 6679341a6fbf9954f7fabc361dc9c2b1 365 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 45 86 - T 12-10-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 VAPA_1c31760 6679341a6fbf9954f7fabc361dc9c2b1 365 Gene3D G3DSA:3.40.140.10 1 139 7.2E-42 T 12-10-2018 VAPA_1c31760 6679341a6fbf9954f7fabc361dc9c2b1 365 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 1 97 7.4E-18 T 12-10-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain VAPA_1c31760 6679341a6fbf9954f7fabc361dc9c2b1 365 SUPERFAMILY SSF53597 143 357 7.85E-56 T 12-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 VAPA_1c31760 6679341a6fbf9954f7fabc361dc9c2b1 365 Pfam PF01872 RibD C-terminal domain 145 353 3.2E-44 T 12-10-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 VAPA_1c31760 6679341a6fbf9954f7fabc361dc9c2b1 365 Gene3D G3DSA:3.40.430.10 140 360 6.5E-64 T 12-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 VAPA_1c31760 6679341a6fbf9954f7fabc361dc9c2b1 365 PIRSF PIRSF006769 1 361 2.0E-117 T 12-10-2018 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-7991 VAPA_1c31760 6679341a6fbf9954f7fabc361dc9c2b1 365 TIGRFAM TIGR00227 ribD_Cterm: riboflavin-specific deaminase C-terminal domain 144 358 2.1E-52 T 12-10-2018 IPR011549 Riboflavin-specific deaminase, C-terminal GO:0008703|GO:0009231|GO:0050661|GO:0055114 VAPA_2c08580 667af0f00b58787c75e3faa0d862cf0d 704 Pfam PF12801 4Fe-4S binding domain 486 530 2.0E-13 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain VAPA_2c08580 667af0f00b58787c75e3faa0d862cf0d 704 Pfam PF12801 4Fe-4S binding domain 587 624 0.0072 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain VAPA_2c08580 667af0f00b58787c75e3faa0d862cf0d 704 PIRSF PIRSF036354 3 703 3.1E-162 T 12-10-2018 IPR011399 Nitrous oxide reductase expression regulator NosR GO:0003677|GO:0016020|GO:0045893 VAPA_2c08580 667af0f00b58787c75e3faa0d862cf0d 704 SUPERFAMILY SSF54862 504 672 2.96E-8 T 12-10-2018 VAPA_2c08580 667af0f00b58787c75e3faa0d862cf0d 704 SMART SM00900 79 178 2.9E-6 T 12-10-2018 IPR007329 FMN-binding GO:0010181|GO:0016020 VAPA_2c08580 667af0f00b58787c75e3faa0d862cf0d 704 Pfam PF04205 FMN-binding domain 79 169 1.4E-4 T 12-10-2018 IPR007329 FMN-binding GO:0010181|GO:0016020 VAPA_1c07390 2bb70fa209b344b947b2337103802140 232 Gene3D G3DSA:3.30.190.20 21 225 1.3E-75 T 12-10-2018 VAPA_1c07390 2bb70fa209b344b947b2337103802140 232 TIGRFAM TIGR01169 rplA_bact: ribosomal protein uL1 3 228 4.9E-101 T 12-10-2018 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 VAPA_1c07390 2bb70fa209b344b947b2337103802140 232 SUPERFAMILY SSF56808 6 226 2.22E-79 T 12-10-2018 IPR023674 Ribosomal protein L1-like VAPA_1c07390 2bb70fa209b344b947b2337103802140 232 Gene3D G3DSA:3.40.50.790 68 159 1.3E-75 T 12-10-2018 IPR016095 Ribosomal protein L1, 3-layer alpha/beta-sandwich VAPA_1c07390 2bb70fa209b344b947b2337103802140 232 Hamap MF_01318_B 50S ribosomal protein L1 [rplA]. 2 229 42.498 T 12-10-2018 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 VAPA_1c07390 2bb70fa209b344b947b2337103802140 232 ProSitePatterns PS01199 Ribosomal protein L1 signature. 121 139 - T 12-10-2018 IPR023673 Ribosomal protein L1, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VAPA_1c07390 2bb70fa209b344b947b2337103802140 232 Pfam PF00687 Ribosomal protein L1p/L10e family 31 219 7.2E-48 T 12-10-2018 IPR028364 Ribosomal protein L1/ribosomal biogenesis protein VAPA_1c07390 2bb70fa209b344b947b2337103802140 232 PIRSF PIRSF002155 1 227 1.1E-75 T 12-10-2018 IPR002143 Ribosomal protein L1 GO:0003723|GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VAPA_2c10090 c6a85c3b79404ae345b9aa6de0fb45ae 138 Pfam PF01042 Endoribonuclease L-PSP 26 135 5.2E-25 T 12-10-2018 IPR006175 YjgF/YER057c/UK114 family Reactome: R-HSA-8849175 VAPA_2c10090 c6a85c3b79404ae345b9aa6de0fb45ae 138 Gene3D G3DSA:3.30.1330.40 16 137 5.4E-32 T 12-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 VAPA_2c10090 c6a85c3b79404ae345b9aa6de0fb45ae 138 SUPERFAMILY SSF55298 18 135 3.61E-31 T 12-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 VAPA_1c22200 ba9c38df6c97d5324cdfa41db3dcccae 371 Gene3D G3DSA:2.40.420.20 39 355 7.3E-64 T 12-10-2018 VAPA_1c22200 ba9c38df6c97d5324cdfa41db3dcccae 371 SUPERFAMILY SSF111369 51 220 7.98E-20 T 12-10-2018 VAPA_1c22200 ba9c38df6c97d5324cdfa41db3dcccae 371 Gene3D G3DSA:2.40.30.170 46 279 7.3E-64 T 12-10-2018 VAPA_1c22200 ba9c38df6c97d5324cdfa41db3dcccae 371 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 59 261 1.0E-14 T 12-10-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain VAPA_1c22200 ba9c38df6c97d5324cdfa41db3dcccae 371 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 47 357 1.7E-62 T 12-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 VAPA_1c22200 ba9c38df6c97d5324cdfa41db3dcccae 371 Gene3D G3DSA:2.40.50.100 60 206 7.3E-64 T 12-10-2018 VAPA_1c22200 ba9c38df6c97d5324cdfa41db3dcccae 371 Gene3D G3DSA:1.10.287.470 94 166 7.3E-64 T 12-10-2018 VAPA_1c42330 af8a52840bcd55f1435c22b54ff12c9e 237 Pfam PF09992 Phosphodiester glycosidase 68 213 2.0E-16 T 12-10-2018 IPR018711 Phosphodiester glycosidase VAPA_1c26770 bebec6662d67a86b3fb7affa3dc763a5 221 Gene3D G3DSA:1.10.3720.10 1 217 9.5E-52 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c26770 bebec6662d67a86b3fb7affa3dc763a5 221 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 12 110 3.1E-23 T 12-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 VAPA_1c26770 bebec6662d67a86b3fb7affa3dc763a5 221 SUPERFAMILY SSF161098 13 213 1.07E-43 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c26770 bebec6662d67a86b3fb7affa3dc763a5 221 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 34 215 1.5E-17 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 VAPA_1c04850 2c223e3a7b86ff2d68bf817ba9665077 198 Pfam PF04355 SmpA / OmlA family 61 127 2.8E-24 T 12-10-2018 IPR007450 Lipoprotein SmpA/OmlA GO:0019867 VAPA_1c04850 2c223e3a7b86ff2d68bf817ba9665077 198 Hamap MF_00925 Outer membrane protein assembly factor BamE [bamE]. 24 171 25.903 T 12-10-2018 IPR026592 Outer membrane protein assembly factor BamE VAPA_1c04850 2c223e3a7b86ff2d68bf817ba9665077 198 Gene3D G3DSA:3.30.1450.10 67 142 4.2E-29 T 12-10-2018 IPR037873 BamE-like VAPA_1c43080 56fcd214a502f1434ac24d27e246078b 359 SUPERFAMILY SSF52738 163 350 2.22E-73 T 12-10-2018 IPR035909 Methylesterase CheB, C-terminal VAPA_1c43080 56fcd214a502f1434ac24d27e246078b 359 Gene3D G3DSA:3.40.50.180 157 354 4.0E-79 T 12-10-2018 IPR035909 Methylesterase CheB, C-terminal VAPA_1c43080 56fcd214a502f1434ac24d27e246078b 359 PIRSF PIRSF000876 1 354 1.3E-136 T 12-10-2018 IPR008248 Signal transduction response regulator, chemotaxis, CheB GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 VAPA_1c43080 56fcd214a502f1434ac24d27e246078b 359 SMART SM00448 4 116 3.0E-23 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_1c43080 56fcd214a502f1434ac24d27e246078b 359 SUPERFAMILY SSF52172 1 108 2.56E-29 T 12-10-2018 IPR011006 CheY-like superfamily VAPA_1c43080 56fcd214a502f1434ac24d27e246078b 359 Pfam PF00072 Response regulator receiver domain 6 108 4.8E-25 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_1c43080 56fcd214a502f1434ac24d27e246078b 359 Pfam PF01339 CheB methylesterase 167 344 5.1E-61 T 12-10-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 VAPA_1c43080 56fcd214a502f1434ac24d27e246078b 359 Gene3D G3DSA:3.40.50.2300 1 133 7.2E-32 T 12-10-2018 VAPA_1c43080 56fcd214a502f1434ac24d27e246078b 359 Hamap MF_00099 Chemotaxis response regulator protein-glutamate methylesterase [cheB]. 4 350 41.287 T 12-10-2018 IPR008248 Signal transduction response regulator, chemotaxis, CheB GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 VAPA_1c10620 3e3ad5a271ba7398e237e857e6895b21 931 SUPERFAMILY SSF48452 742 806 2.35E-5 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 VAPA_1c10620 3e3ad5a271ba7398e237e857e6895b21 931 SUPERFAMILY SSF52540 74 273 1.96E-9 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c10620 3e3ad5a271ba7398e237e857e6895b21 931 Gene3D G3DSA:1.10.10.10 866 931 7.6E-23 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c10620 3e3ad5a271ba7398e237e857e6895b21 931 ProSitePatterns PS00622 LuxR-type HTH domain signature. 888 915 - T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_1c10620 3e3ad5a271ba7398e237e857e6895b21 931 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 874 888 4.4E-13 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_1c10620 3e3ad5a271ba7398e237e857e6895b21 931 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 888 904 4.4E-13 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_1c10620 3e3ad5a271ba7398e237e857e6895b21 931 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 904 916 4.4E-13 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_1c10620 3e3ad5a271ba7398e237e857e6895b21 931 SUPERFAMILY SSF46894 868 930 1.16E-18 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 VAPA_1c10620 3e3ad5a271ba7398e237e857e6895b21 931 Pfam PF00196 Bacterial regulatory proteins, luxR family 873 926 2.9E-18 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_1c10620 3e3ad5a271ba7398e237e857e6895b21 931 Gene3D G3DSA:3.40.50.300 46 220 3.0E-11 T 12-10-2018 VAPA_1c10620 3e3ad5a271ba7398e237e857e6895b21 931 Pfam PF13191 AAA ATPase domain 62 206 1.4E-9 T 12-10-2018 VAPA_1c10620 3e3ad5a271ba7398e237e857e6895b21 931 Gene3D G3DSA:1.25.40.10 599 851 4.4E-10 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 VAPA_1c10620 3e3ad5a271ba7398e237e857e6895b21 931 Gene3D G3DSA:1.25.40.10 403 561 1.9E-6 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 VAPA_1c10620 3e3ad5a271ba7398e237e857e6895b21 931 SMART SM00421 871 928 7.5E-21 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_2c02090 07ac8c30db4ee7d805e54f64621a8614 450 Pfam PF15652 HNH/Endo VII superfamily toxin with a SHH signature 345 444 1.0E-26 T 12-10-2018 IPR028900 Tox-SHH domain VAPA_2c02090 07ac8c30db4ee7d805e54f64621a8614 450 PRINTS PR00394 RHS protein signature 197 217 1.6E-5 T 12-10-2018 IPR001826 RHS protein VAPA_2c02090 07ac8c30db4ee7d805e54f64621a8614 450 PRINTS PR00394 RHS protein signature 279 298 1.6E-5 T 12-10-2018 IPR001826 RHS protein VAPA_2c02090 07ac8c30db4ee7d805e54f64621a8614 450 Gene3D G3DSA:2.180.10.10 13 311 1.4E-37 T 12-10-2018 VAPA_2c02090 07ac8c30db4ee7d805e54f64621a8614 450 TIGRFAM TIGR03696 Rhs_assc_core: RHS repeat-associated core domain 230 311 1.5E-27 T 12-10-2018 IPR022385 Rhs repeat-associated core GO:0097264 VAPA_2c02090 07ac8c30db4ee7d805e54f64621a8614 450 Pfam PF03527 RHS protein 203 237 8.5E-18 T 12-10-2018 IPR001826 RHS protein VAPA_1c17830 a29b043ad120cabea919e12a1e7fdb06 485 Gene3D G3DSA:3.40.50.720 8 192 3.1E-57 T 12-10-2018 VAPA_1c17830 a29b043ad120cabea919e12a1e7fdb06 485 ProSitePatterns PS00461 6-phosphogluconate dehydrogenase signature. 265 277 - T 12-10-2018 IPR006184 6-phosphogluconate-binding site GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 VAPA_1c17830 a29b043ad120cabea919e12a1e7fdb06 485 PIRSF PIRSF000109 11 485 5.9E-220 T 12-10-2018 IPR006113 6-phosphogluconate dehydrogenase, decarboxylating GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 VAPA_1c17830 a29b043ad120cabea919e12a1e7fdb06 485 TIGRFAM TIGR00873 gnd: 6-phosphogluconate dehydrogenase (decarboxylating) 18 481 1.2E-216 T 12-10-2018 IPR006113 6-phosphogluconate dehydrogenase, decarboxylating GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 VAPA_1c17830 a29b043ad120cabea919e12a1e7fdb06 485 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 180 208 1.5E-81 T 12-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 VAPA_1c17830 a29b043ad120cabea919e12a1e7fdb06 485 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 79 108 1.5E-81 T 12-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 VAPA_1c17830 a29b043ad120cabea919e12a1e7fdb06 485 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 368 390 1.5E-81 T 12-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 VAPA_1c17830 a29b043ad120cabea919e12a1e7fdb06 485 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 17 40 1.5E-81 T 12-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 VAPA_1c17830 a29b043ad120cabea919e12a1e7fdb06 485 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 132 157 1.5E-81 T 12-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 VAPA_1c17830 a29b043ad120cabea919e12a1e7fdb06 485 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 261 288 1.5E-81 T 12-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 VAPA_1c17830 a29b043ad120cabea919e12a1e7fdb06 485 Pfam PF00393 6-phosphogluconate dehydrogenase, C-terminal domain 191 480 1.2E-127 T 12-10-2018 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 VAPA_1c17830 a29b043ad120cabea919e12a1e7fdb06 485 Gene3D G3DSA:1.20.5.320 448 480 2.0E-19 T 12-10-2018 VAPA_1c17830 a29b043ad120cabea919e12a1e7fdb06 485 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 19 183 6.0E-52 T 12-10-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 VAPA_1c17830 a29b043ad120cabea919e12a1e7fdb06 485 SMART SM01350 191 481 8.1E-207 T 12-10-2018 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 VAPA_1c17830 a29b043ad120cabea919e12a1e7fdb06 485 SUPERFAMILY SSF51735 18 188 4.86E-52 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c17830 a29b043ad120cabea919e12a1e7fdb06 485 Gene3D G3DSA:1.10.1040.10 193 446 2.0E-106 T 12-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 VAPA_1c17830 a29b043ad120cabea919e12a1e7fdb06 485 SUPERFAMILY SSF48179 189 482 4.04E-122 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 VAPA_2c11620 120949c10c4f34a6f0f5c0c989ad7ae7 315 TIGRFAM TIGR03431 PhnD: phosphonate ABC transporter, periplasmic phosphonate binding protein 1 283 7.9E-103 T 12-10-2018 IPR017797 Phosphonate ABC transporter, substrate-binding protein GO:0015716|GO:0043190 VAPA_2c11620 120949c10c4f34a6f0f5c0c989ad7ae7 315 Gene3D G3DSA:1.20.58.90 271 315 4.3E-13 T 12-10-2018 VAPA_2c11620 120949c10c4f34a6f0f5c0c989ad7ae7 315 Gene3D G3DSA:3.40.190.10 26 251 9.4E-92 T 12-10-2018 VAPA_2c11620 120949c10c4f34a6f0f5c0c989ad7ae7 315 SUPERFAMILY SSF53850 45 237 8.65E-38 T 12-10-2018 VAPA_2c11620 120949c10c4f34a6f0f5c0c989ad7ae7 315 Gene3D G3DSA:3.40.190.10 109 221 9.4E-92 T 12-10-2018 VAPA_2c11620 120949c10c4f34a6f0f5c0c989ad7ae7 315 TIGRFAM TIGR01098 3A0109s03R: phosphate/phosphite/phosphonate ABC transporter, periplasmic binding protein 21 246 4.0E-84 T 12-10-2018 IPR005770 Phosphate/phosphite/phosphonate ABC transporter, periplasmic binding protein GO:0043190|GO:0055085 VAPA_2c11620 120949c10c4f34a6f0f5c0c989ad7ae7 315 Pfam PF12974 ABC transporter, phosphonate, periplasmic substrate-binding protein 26 273 1.1E-62 T 12-10-2018 VAPA_1c54940 9e21c7527482e7c5aa69399ffa4bfbd4 265 Pfam PF01904 Protein of unknown function DUF72 30 254 1.2E-56 T 12-10-2018 IPR002763 Protein of unknown function DUF72 VAPA_1c54940 9e21c7527482e7c5aa69399ffa4bfbd4 265 Gene3D G3DSA:3.20.20.410 2 258 8.0E-55 T 12-10-2018 IPR036520 UPF0759 superfamily VAPA_1c54940 9e21c7527482e7c5aa69399ffa4bfbd4 265 SUPERFAMILY SSF117396 12 257 2.62E-69 T 12-10-2018 IPR036520 UPF0759 superfamily VAPA_1c22290 fa33b3b5c1216f426d0f77cc194a9778 309 Pfam PF00005 ABC transporter 33 173 5.5E-29 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c22290 fa33b3b5c1216f426d0f77cc194a9778 309 SUPERFAMILY SSF52540 15 231 8.05E-66 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c22290 fa33b3b5c1216f426d0f77cc194a9778 309 SMART SM00382 41 223 4.4E-16 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c22290 fa33b3b5c1216f426d0f77cc194a9778 309 Gene3D G3DSA:3.40.50.300 13 255 3.3E-61 T 12-10-2018 VAPA_1c22290 fa33b3b5c1216f426d0f77cc194a9778 309 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_1c22340 777a2d2ee449fd4e6593715941d7a123 189 SUPERFAMILY SSF82784 20 186 1.57E-30 T 12-10-2018 IPR036102 OsmC/Ohr superfamily VAPA_1c22340 777a2d2ee449fd4e6593715941d7a123 189 Pfam PF02566 OsmC-like protein 78 186 3.5E-21 T 12-10-2018 IPR003718 OsmC/Ohr family VAPA_1c22340 777a2d2ee449fd4e6593715941d7a123 189 Gene3D G3DSA:3.30.300.20 16 178 1.1E-30 T 12-10-2018 IPR015946 K homology domain-like, alpha/beta VAPA_1c49880 c93c3d9315035053c05206535013a222 330 Gene3D G3DSA:3.40.190.150 35 320 5.9E-120 T 12-10-2018 VAPA_1c49880 c93c3d9315035053c05206535013a222 330 Gene3D G3DSA:3.40.190.10 132 255 5.9E-120 T 12-10-2018 VAPA_1c49880 c93c3d9315035053c05206535013a222 330 SUPERFAMILY SSF53850 120 292 3.98E-13 T 12-10-2018 VAPA_1c49880 c93c3d9315035053c05206535013a222 330 PIRSF PIRSF017082 3 330 6.1E-81 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c49880 c93c3d9315035053c05206535013a222 330 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 54 325 7.7E-91 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c43900 1225dd1d3ba8b0df32b8de1922aa686b 932 Pfam PF07517 SecA DEAD-like domain 7 406 9.4E-133 T 12-10-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 VAPA_1c43900 1225dd1d3ba8b0df32b8de1922aa686b 932 Pfam PF07516 SecA Wing and Scaffold domain 628 840 1.3E-63 T 12-10-2018 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 VAPA_1c43900 1225dd1d3ba8b0df32b8de1922aa686b 932 SMART SM00957 6 406 0.0 T 12-10-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 VAPA_1c43900 1225dd1d3ba8b0df32b8de1922aa686b 932 ProSitePatterns PS01312 SecA family signature. 504 519 - T 12-10-2018 IPR020937 SecA conserved site GO:0006605|GO:0006886|GO:0016020 VAPA_1c43900 1225dd1d3ba8b0df32b8de1922aa686b 932 PRINTS PR00906 SecA protein signature 417 430 4.5E-68 T 12-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 VAPA_1c43900 1225dd1d3ba8b0df32b8de1922aa686b 932 PRINTS PR00906 SecA protein signature 63 87 4.5E-68 T 12-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 VAPA_1c43900 1225dd1d3ba8b0df32b8de1922aa686b 932 PRINTS PR00906 SecA protein signature 117 127 4.5E-68 T 12-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 VAPA_1c43900 1225dd1d3ba8b0df32b8de1922aa686b 932 PRINTS PR00906 SecA protein signature 380 397 4.5E-68 T 12-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 VAPA_1c43900 1225dd1d3ba8b0df32b8de1922aa686b 932 PRINTS PR00906 SecA protein signature 343 365 4.5E-68 T 12-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 VAPA_1c43900 1225dd1d3ba8b0df32b8de1922aa686b 932 PRINTS PR00906 SecA protein signature 101 115 4.5E-68 T 12-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 VAPA_1c43900 1225dd1d3ba8b0df32b8de1922aa686b 932 PRINTS PR00906 SecA protein signature 170 190 4.5E-68 T 12-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 VAPA_1c43900 1225dd1d3ba8b0df32b8de1922aa686b 932 Pfam PF01043 SecA preprotein cross-linking domain 232 362 1.7E-38 T 12-10-2018 IPR011130 SecA, preprotein cross-linking domain GO:0016020|GO:0017038 VAPA_1c43900 1225dd1d3ba8b0df32b8de1922aa686b 932 Gene3D G3DSA:1.10.3060.10 632 844 1.7E-72 T 12-10-2018 VAPA_1c43900 1225dd1d3ba8b0df32b8de1922aa686b 932 SUPERFAMILY SSF52540 422 629 2.8E-56 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c43900 1225dd1d3ba8b0df32b8de1922aa686b 932 Gene3D G3DSA:3.40.50.300 422 630 7.3E-82 T 12-10-2018 VAPA_1c43900 1225dd1d3ba8b0df32b8de1922aa686b 932 TIGRFAM TIGR00963 secA: preprotein translocase, SecA subunit 28 828 0.0 T 12-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 VAPA_1c43900 1225dd1d3ba8b0df32b8de1922aa686b 932 Pfam PF02810 SEC-C motif 912 930 1.9E-10 T 12-10-2018 IPR004027 SEC-C motif VAPA_1c43900 1225dd1d3ba8b0df32b8de1922aa686b 932 Gene3D G3DSA:3.90.1440.10 229 372 1.4E-178 T 12-10-2018 VAPA_1c43900 1225dd1d3ba8b0df32b8de1922aa686b 932 SMART SM00958 228 362 1.7E-81 T 12-10-2018 IPR011130 SecA, preprotein cross-linking domain GO:0016020|GO:0017038 VAPA_1c43900 1225dd1d3ba8b0df32b8de1922aa686b 932 Gene3D G3DSA:3.40.50.300 22 419 1.4E-178 T 12-10-2018 VAPA_1c43900 1225dd1d3ba8b0df32b8de1922aa686b 932 Hamap MF_01382 Protein translocase subunit SecA [secA]. 5 843 19.727 T 12-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 VAPA_1c43900 1225dd1d3ba8b0df32b8de1922aa686b 932 Gene3D G3DSA:3.10.450.50 871 931 3.2E-8 T 12-10-2018 VAPA_1c43900 1225dd1d3ba8b0df32b8de1922aa686b 932 SUPERFAMILY SSF81886 633 920 2.09E-77 T 12-10-2018 IPR036266 SecA, Wing/Scaffold superfamily VAPA_1c43900 1225dd1d3ba8b0df32b8de1922aa686b 932 SUPERFAMILY SSF52540 4 419 1.13E-86 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c43900 1225dd1d3ba8b0df32b8de1922aa686b 932 SUPERFAMILY SSF81767 227 372 4.45E-44 T 12-10-2018 IPR036670 SecA, preprotein cross-linking domain superfamily GO:0016020|GO:0017038 VAPA_1c08520 4730dd0b6011572420df6ad5a64e5e84 260 Gene3D G3DSA:1.10.10.10 1 65 6.8E-16 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c08520 4730dd0b6011572420df6ad5a64e5e84 260 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 26 40 8.0E-9 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_1c08520 4730dd0b6011572420df6ad5a64e5e84 260 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 40 56 8.0E-9 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_1c08520 4730dd0b6011572420df6ad5a64e5e84 260 SUPERFAMILY SSF64288 85 238 1.07E-38 T 12-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily VAPA_1c08520 4730dd0b6011572420df6ad5a64e5e84 260 SMART SM00866 95 234 1.0E-34 T 12-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 VAPA_1c08520 4730dd0b6011572420df6ad5a64e5e84 260 SUPERFAMILY SSF46785 3 69 2.73E-15 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c08520 4730dd0b6011572420df6ad5a64e5e84 260 Pfam PF00392 Bacterial regulatory proteins, gntR family 6 65 2.0E-14 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_1c08520 4730dd0b6011572420df6ad5a64e5e84 260 Pfam PF07702 UTRA domain 96 233 2.0E-33 T 12-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 VAPA_1c08520 4730dd0b6011572420df6ad5a64e5e84 260 Gene3D G3DSA:3.40.1410.10 81 242 8.0E-39 T 12-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily VAPA_1c08520 4730dd0b6011572420df6ad5a64e5e84 260 SMART SM00345 9 66 1.4E-9 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_1c50140 e4521977b0467ba487d4688c0a9933c3 248 Pfam PF08362 YcdC-like protein, C-terminal region 106 248 5.9E-57 T 12-10-2018 IPR013573 Transcription regulator YcdC, C-terminal GO:0045892 VAPA_1c50140 e4521977b0467ba487d4688c0a9933c3 248 Gene3D G3DSA:1.10.357.10 106 248 1.7E-52 T 12-10-2018 VAPA_1c50140 e4521977b0467ba487d4688c0a9933c3 248 SUPERFAMILY SSF46689 47 126 9.71E-19 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 VAPA_1c50140 e4521977b0467ba487d4688c0a9933c3 248 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 59 72 1.3E-7 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 VAPA_1c50140 e4521977b0467ba487d4688c0a9933c3 248 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 80 103 1.3E-7 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 VAPA_1c50140 e4521977b0467ba487d4688c0a9933c3 248 SUPERFAMILY SSF48498 123 248 1.47E-42 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily VAPA_1c50140 e4521977b0467ba487d4688c0a9933c3 248 Gene3D G3DSA:1.10.10.60 38 105 8.5E-22 T 12-10-2018 VAPA_1c50140 e4521977b0467ba487d4688c0a9933c3 248 Pfam PF00440 Bacterial regulatory proteins, tetR family 59 102 4.9E-13 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 VAPA_1c35920 677190e9675c84820284536a67017ae7 291 Pfam PF02653 Branched-chain amino acid transport system / permease component 13 279 2.5E-39 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 VAPA_1c25200 99381de25265ef8f46fec9a062159cef 119 SUPERFAMILY SSF54593 3 119 4.13E-23 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase VAPA_1c25200 99381de25265ef8f46fec9a062159cef 119 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 3 115 3.3E-5 T 12-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain VAPA_1c25200 99381de25265ef8f46fec9a062159cef 119 Gene3D G3DSA:3.10.180.10 1 119 1.1E-35 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase VAPA_2c04540 e07582206d50eb3c8918efa126263dbf 1262 Gene3D G3DSA:4.10.1200.10 1 26 8.0E-7 T 12-10-2018 VAPA_2c04540 e07582206d50eb3c8918efa126263dbf 1262 Pfam PF00384 Molybdopterin oxidoreductase 108 843 6.9E-157 T 12-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VAPA_2c04540 e07582206d50eb3c8918efa126263dbf 1262 Pfam PF14710 Respiratory nitrate reductase alpha N-terminal 3 40 3.6E-18 T 12-10-2018 IPR028189 Nitrate reductase, alpha subunit, N-terminal KEGG: 00910+1.7.5.1|MetaCyc: PWY-6748 VAPA_2c04540 e07582206d50eb3c8918efa126263dbf 1262 SMART SM00926 43 105 1.3E-8 T 12-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VAPA_2c04540 e07582206d50eb3c8918efa126263dbf 1262 SUPERFAMILY SSF53706 3 1087 0.0 T 12-10-2018 VAPA_2c04540 e07582206d50eb3c8918efa126263dbf 1262 TIGRFAM TIGR01580 narG: nitrate reductase, alpha subunit 2 1248 0.0 T 12-10-2018 IPR006468 Nitrate reductase, alpha subunit GO:0008940|GO:0009325|GO:0042126|GO:0055114 KEGG: 00910+1.7.5.1|MetaCyc: PWY-6748 VAPA_2c04540 e07582206d50eb3c8918efa126263dbf 1262 Gene3D G3DSA:3.40.50.12440 44 1257 0.0 T 12-10-2018 VAPA_2c04540 e07582206d50eb3c8918efa126263dbf 1262 ProSitePatterns PS00490 Prokaryotic molybdopterin oxidoreductases signature 2. 789 806 - T 12-10-2018 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 VAPA_2c04540 e07582206d50eb3c8918efa126263dbf 1262 ProSitePatterns PS00932 Prokaryotic molybdopterin oxidoreductases signature 3. 1138 1165 - T 12-10-2018 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 VAPA_2c04540 e07582206d50eb3c8918efa126263dbf 1262 SUPERFAMILY SSF50692 1095 1249 4.97E-47 T 12-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily VAPA_2c04540 e07582206d50eb3c8918efa126263dbf 1262 Pfam PF01568 Molydopterin dinucleotide binding domain 1100 1215 3.8E-23 T 12-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 VAPA_1c52380 5bf6a8d0ca8687383d953596873b2999 207 Pfam PF00163 Ribosomal protein S4/S9 N-terminal domain 3 96 1.9E-30 T 12-10-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 VAPA_1c52380 5bf6a8d0ca8687383d953596873b2999 207 SMART SM01390 3 96 1.2E-46 T 12-10-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 VAPA_1c52380 5bf6a8d0ca8687383d953596873b2999 207 SMART SM00363 97 161 6.0E-20 T 12-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VAPA_1c52380 5bf6a8d0ca8687383d953596873b2999 207 SUPERFAMILY SSF55174 3 207 1.27E-69 T 12-10-2018 VAPA_1c52380 5bf6a8d0ca8687383d953596873b2999 207 Hamap MF_01306_B 30S ribosomal protein S4 [rpsD]. 1 207 35.498 T 12-10-2018 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 VAPA_1c52380 5bf6a8d0ca8687383d953596873b2999 207 Gene3D G3DSA:3.10.290.10 96 192 3.1E-80 T 12-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 VAPA_1c52380 5bf6a8d0ca8687383d953596873b2999 207 TIGRFAM TIGR01017 rpsD_bact: ribosomal protein uS4 3 207 7.5E-83 T 12-10-2018 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 VAPA_1c52380 5bf6a8d0ca8687383d953596873b2999 207 Gene3D G3DSA:1.10.1050.10 6 207 3.1E-80 T 12-10-2018 VAPA_1c52380 5bf6a8d0ca8687383d953596873b2999 207 ProSitePatterns PS00632 Ribosomal protein S4 signature. 95 119 - T 12-10-2018 IPR018079 Ribosomal protein S4, conserved site GO:0005622|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VAPA_1c52380 5bf6a8d0ca8687383d953596873b2999 207 Pfam PF01479 S4 domain 98 144 2.0E-20 T 12-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VAPA_1c22460 162b77d0783cfad179e7021c726f2b13 243 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 23 129 2.3E-18 T 12-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 VAPA_1c22460 162b77d0783cfad179e7021c726f2b13 243 Gene3D G3DSA:1.10.3720.10 18 235 7.6E-46 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c22460 162b77d0783cfad179e7021c726f2b13 243 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 45 232 1.1E-18 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 VAPA_1c22460 162b77d0783cfad179e7021c726f2b13 243 SUPERFAMILY SSF161098 24 220 3.66E-38 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c26220 8d3fae577063ee000f304ffe96b26727 409 Pfam PF13458 Periplasmic binding protein 27 371 4.6E-64 T 12-10-2018 IPR028081 Leucine-binding protein domain VAPA_1c26220 8d3fae577063ee000f304ffe96b26727 409 Gene3D G3DSA:3.40.50.2300 153 404 1.5E-132 T 12-10-2018 VAPA_1c26220 8d3fae577063ee000f304ffe96b26727 409 SUPERFAMILY SSF53822 26 372 7.06E-63 T 12-10-2018 IPR028082 Periplasmic binding protein-like I VAPA_1c26220 8d3fae577063ee000f304ffe96b26727 409 Gene3D G3DSA:3.40.50.2300 27 362 1.5E-132 T 12-10-2018 VAPA_1c10940 4d86666bf2c624a1c9bf13d9ff7772d1 258 Gene3D G3DSA:3.40.50.720 7 258 8.6E-65 T 12-10-2018 VAPA_1c10940 4d86666bf2c624a1c9bf13d9ff7772d1 258 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 152 180 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 VAPA_1c10940 4d86666bf2c624a1c9bf13d9ff7772d1 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 145 153 3.1E-6 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c10940 4d86666bf2c624a1c9bf13d9ff7772d1 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 92 103 3.1E-6 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c10940 4d86666bf2c624a1c9bf13d9ff7772d1 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 165 184 3.1E-6 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c10940 4d86666bf2c624a1c9bf13d9ff7772d1 258 SUPERFAMILY SSF51735 14 258 1.86E-67 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c10940 4d86666bf2c624a1c9bf13d9ff7772d1 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 139 155 7.4E-29 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c10940 4d86666bf2c624a1c9bf13d9ff7772d1 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 165 184 7.4E-29 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c10940 4d86666bf2c624a1c9bf13d9ff7772d1 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 17 34 7.4E-29 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c10940 4d86666bf2c624a1c9bf13d9ff7772d1 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 92 103 7.4E-29 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c10940 4d86666bf2c624a1c9bf13d9ff7772d1 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 186 203 7.4E-29 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c10940 4d86666bf2c624a1c9bf13d9ff7772d1 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 221 241 7.4E-29 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c10940 4d86666bf2c624a1c9bf13d9ff7772d1 258 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 25 258 2.0E-55 T 12-10-2018 VAPA_1c00560 08affb65d82ed926ef26a5237a078017 212 SUPERFAMILY SSF52266 37 207 1.83E-35 T 12-10-2018 VAPA_1c00560 08affb65d82ed926ef26a5237a078017 212 Gene3D G3DSA:3.40.50.1110 35 210 4.7E-43 T 12-10-2018 IPR036514 SGNH hydrolase superfamily VAPA_1c00560 08affb65d82ed926ef26a5237a078017 212 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 40 197 2.8E-22 T 12-10-2018 IPR013830 SGNH hydrolase-type esterase domain VAPA_1c16610 3a2bfc9430269b5393d0910d0ff7dc8e 302 Gene3D G3DSA:3.40.250.10 1 164 2.6E-43 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily VAPA_1c16610 3a2bfc9430269b5393d0910d0ff7dc8e 302 SUPERFAMILY SSF52821 3 157 1.01E-32 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily VAPA_1c16610 3a2bfc9430269b5393d0910d0ff7dc8e 302 Pfam PF00581 Rhodanese-like domain 176 290 1.8E-8 T 12-10-2018 IPR001763 Rhodanese-like domain VAPA_1c16610 3a2bfc9430269b5393d0910d0ff7dc8e 302 Pfam PF00581 Rhodanese-like domain 8 147 8.6E-13 T 12-10-2018 IPR001763 Rhodanese-like domain VAPA_1c16610 3a2bfc9430269b5393d0910d0ff7dc8e 302 Gene3D G3DSA:3.40.250.10 178 300 3.7E-30 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily VAPA_1c16610 3a2bfc9430269b5393d0910d0ff7dc8e 302 SMART SM00450 174 294 1.1E-8 T 12-10-2018 IPR001763 Rhodanese-like domain VAPA_1c16610 3a2bfc9430269b5393d0910d0ff7dc8e 302 SMART SM00450 6 150 6.3E-13 T 12-10-2018 IPR001763 Rhodanese-like domain VAPA_1c16610 3a2bfc9430269b5393d0910d0ff7dc8e 302 SUPERFAMILY SSF52821 177 300 6.68E-31 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily VAPA_2c04490 994c46f2f5662e8fc5bb57ae9dc9d603 226 ProSitePatterns PS00704 Prokaryotic-type carbonic anhydrases signature 1. 45 52 - T 12-10-2018 IPR015892 Carbonic anhydrase, prokaryotic-like, conserved site GO:0004089|GO:0008270|GO:0015976 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 VAPA_2c04490 994c46f2f5662e8fc5bb57ae9dc9d603 226 ProSitePatterns PS00705 Prokaryotic-type carbonic anhydrases signature 2. 90 110 - T 12-10-2018 IPR015892 Carbonic anhydrase, prokaryotic-like, conserved site GO:0004089|GO:0008270|GO:0015976 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 VAPA_2c04490 994c46f2f5662e8fc5bb57ae9dc9d603 226 Gene3D G3DSA:3.40.1050.10 1 202 3.4E-61 T 12-10-2018 IPR036874 Carbonic anhydrase superfamily GO:0004089|GO:0008270 VAPA_2c04490 994c46f2f5662e8fc5bb57ae9dc9d603 226 SMART SM00947 33 195 6.9E-62 T 12-10-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 VAPA_2c04490 994c46f2f5662e8fc5bb57ae9dc9d603 226 Pfam PF00484 Carbonic anhydrase 40 191 1.8E-47 T 12-10-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 VAPA_2c04490 994c46f2f5662e8fc5bb57ae9dc9d603 226 SUPERFAMILY SSF53056 5 203 1.7E-56 T 12-10-2018 IPR036874 Carbonic anhydrase superfamily GO:0004089|GO:0008270 VAPA_2c02350 2501d59c71662aad0a852efae3254cb7 305 Gene3D G3DSA:3.40.50.720 43 299 1.2E-50 T 12-10-2018 VAPA_2c02350 2501d59c71662aad0a852efae3254cb7 305 SUPERFAMILY SSF51735 1 133 8.73E-28 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_2c02350 2501d59c71662aad0a852efae3254cb7 305 SMART SM00859 4 104 6.4E-14 T 12-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 VAPA_2c02350 2501d59c71662aad0a852efae3254cb7 305 SUPERFAMILY SSF55347 115 285 5.23E-34 T 12-10-2018 VAPA_2c02350 2501d59c71662aad0a852efae3254cb7 305 Gene3D G3DSA:3.30.360.10 119 290 1.2E-50 T 12-10-2018 VAPA_2c02350 2501d59c71662aad0a852efae3254cb7 305 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 42 99 2.0E-10 T 12-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 VAPA_2c02350 2501d59c71662aad0a852efae3254cb7 305 TIGRFAM TIGR01851 argC_other: N-acetyl-gamma-glutamyl-phosphate reductase 4 299 1.1E-103 T 12-10-2018 IPR010136 N-acetyl-gamma-glutamyl-phosphate reductase, type 2 GO:0003942|GO:0005737|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 VAPA_2c02730 aef9287dac789e6ddd25e05c138c086f 482 Gene3D G3DSA:1.20.1250.20 260 476 2.9E-16 T 12-10-2018 VAPA_2c02730 aef9287dac789e6ddd25e05c138c086f 482 Gene3D G3DSA:1.20.1720.10 15 256 1.3E-47 T 12-10-2018 VAPA_2c02730 aef9287dac789e6ddd25e05c138c086f 482 Pfam PF07690 Major Facilitator Superfamily 21 411 7.0E-45 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 VAPA_2c02730 aef9287dac789e6ddd25e05c138c086f 482 SUPERFAMILY SSF103473 6 474 1.83E-59 T 12-10-2018 IPR036259 MFS transporter superfamily VAPA_2c02730 aef9287dac789e6ddd25e05c138c086f 482 PRINTS PR01036 Tetracycline resistance protein TetB signature 139 163 1.6E-5 T 12-10-2018 VAPA_2c02730 aef9287dac789e6ddd25e05c138c086f 482 PRINTS PR01036 Tetracycline resistance protein TetB signature 109 129 1.6E-5 T 12-10-2018 VAPA_2c02730 aef9287dac789e6ddd25e05c138c086f 482 PRINTS PR01036 Tetracycline resistance protein TetB signature 18 42 1.6E-5 T 12-10-2018 VAPA_1c17620 8d99d523873efe6aeefa8d410905bef0 221 SUPERFAMILY SSF51735 2 206 3.64E-28 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c17620 8d99d523873efe6aeefa8d410905bef0 221 Gene3D G3DSA:3.40.50.720 1 221 6.6E-39 T 12-10-2018 VAPA_1c37070 3a2c3625994ed1a18a73cbd147e30f57 885 PIRSF PIRSF037677 10 858 1.5E-142 T 12-10-2018 IPR017261 DNA mismatch repair protein MutS/MSH GO:0006298|GO:0030983 VAPA_1c37070 3a2c3625994ed1a18a73cbd147e30f57 885 Gene3D G3DSA:1.10.1420.10 286 582 1.5E-90 T 12-10-2018 VAPA_1c37070 3a2c3625994ed1a18a73cbd147e30f57 885 SMART SM00534 633 820 6.4E-102 T 12-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 VAPA_1c37070 3a2c3625994ed1a18a73cbd147e30f57 885 Gene3D G3DSA:3.40.50.300 593 878 1.2E-93 T 12-10-2018 VAPA_1c37070 3a2c3625994ed1a18a73cbd147e30f57 885 Pfam PF05190 MutS family domain IV 451 541 9.8E-30 T 12-10-2018 IPR007861 DNA mismatch repair protein MutS, clamp GO:0005524|GO:0006298|GO:0030983 VAPA_1c37070 3a2c3625994ed1a18a73cbd147e30f57 885 SUPERFAMILY SSF53150 125 283 1.31E-29 T 12-10-2018 IPR036678 MutS, connector domain superfamily GO:0005524|GO:0006298|GO:0030983 VAPA_1c37070 3a2c3625994ed1a18a73cbd147e30f57 885 Pfam PF01624 MutS domain I 19 131 4.7E-40 T 12-10-2018 IPR007695 DNA mismatch repair protein MutS-like, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 VAPA_1c37070 3a2c3625994ed1a18a73cbd147e30f57 885 Gene3D G3DSA:3.40.1170.10 11 132 9.9E-48 T 12-10-2018 IPR016151 DNA mismatch repair protein MutS, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 VAPA_1c37070 3a2c3625994ed1a18a73cbd147e30f57 885 Gene3D G3DSA:1.10.1420.10 422 557 1.5E-90 T 12-10-2018 VAPA_1c37070 3a2c3625994ed1a18a73cbd147e30f57 885 TIGRFAM TIGR01070 mutS1: DNA mismatch repair protein MutS 18 876 1.6E-298 T 12-10-2018 IPR005748 DNA mismatch repair protein MutS GO:0005524|GO:0006298|GO:0030983 VAPA_1c37070 3a2c3625994ed1a18a73cbd147e30f57 885 Pfam PF00488 MutS domain V 636 823 4.2E-79 T 12-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 VAPA_1c37070 3a2c3625994ed1a18a73cbd147e30f57 885 Pfam PF05192 MutS domain III 287 581 5.6E-30 T 12-10-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 VAPA_1c37070 3a2c3625994ed1a18a73cbd147e30f57 885 Hamap MF_00096 DNA mismatch repair protein MutS [mutS]. 18 870 23.08 T 12-10-2018 IPR005748 DNA mismatch repair protein MutS GO:0005524|GO:0006298|GO:0030983 VAPA_1c37070 3a2c3625994ed1a18a73cbd147e30f57 885 Gene3D G3DSA:3.30.420.110 140 279 9.3E-23 T 12-10-2018 IPR036678 MutS, connector domain superfamily GO:0005524|GO:0006298|GO:0030983 VAPA_1c37070 3a2c3625994ed1a18a73cbd147e30f57 885 SUPERFAMILY SSF52540 589 824 9.63E-56 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c37070 3a2c3625994ed1a18a73cbd147e30f57 885 SUPERFAMILY SSF48334 287 586 2.22E-78 T 12-10-2018 IPR036187 DNA mismatch repair protein MutS, core domain superfamily VAPA_1c37070 3a2c3625994ed1a18a73cbd147e30f57 885 ProSitePatterns PS00486 DNA mismatch repair proteins mutS family signature. 714 730 - T 12-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 VAPA_1c37070 3a2c3625994ed1a18a73cbd147e30f57 885 Pfam PF05188 MutS domain II 140 271 1.0E-13 T 12-10-2018 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 VAPA_1c37070 3a2c3625994ed1a18a73cbd147e30f57 885 SUPERFAMILY SSF55271 13 126 9.29E-42 T 12-10-2018 IPR016151 DNA mismatch repair protein MutS, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 VAPA_1c37070 3a2c3625994ed1a18a73cbd147e30f57 885 SMART SM00533 301 613 2.0E-83 T 12-10-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 VAPA_1c47080 ae6560ae150a6b222b84b4cbf9c19504 730 SUPERFAMILY SSF90123 156 468 1.27E-53 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 VAPA_1c47080 ae6560ae150a6b222b84b4cbf9c19504 730 Gene3D G3DSA:1.20.1560.10 157 467 2.3E-57 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 VAPA_1c47080 ae6560ae150a6b222b84b4cbf9c19504 730 Pfam PF00664 ABC transporter transmembrane region 171 435 8.2E-24 T 12-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 VAPA_1c47080 ae6560ae150a6b222b84b4cbf9c19504 730 Pfam PF00005 ABC transporter 504 648 4.0E-30 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c47080 ae6560ae150a6b222b84b4cbf9c19504 730 Gene3D G3DSA:3.90.70.10 19 137 6.5E-14 T 12-10-2018 VAPA_1c47080 ae6560ae150a6b222b84b4cbf9c19504 730 SMART SM00382 508 694 2.6E-17 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c47080 ae6560ae150a6b222b84b4cbf9c19504 730 SUPERFAMILY SSF52540 474 707 1.9E-61 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c47080 ae6560ae150a6b222b84b4cbf9c19504 730 Gene3D G3DSA:3.40.50.300 476 724 5.3E-73 T 12-10-2018 VAPA_1c47080 ae6560ae150a6b222b84b4cbf9c19504 730 TIGRFAM TIGR03375 type_I_sec_LssB: type I secretion system ATPase 21 711 5.4E-237 T 12-10-2018 IPR017750 ATPase, type I secretion system VAPA_2c08530 038e23291ba2e6683852655b40658918 664 Pfam PF13193 AMP-binding enzyme C-terminal domain 547 629 6.0E-25 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain VAPA_2c08530 038e23291ba2e6683852655b40658918 664 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 35 90 3.2E-17 T 12-10-2018 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857 VAPA_2c08530 038e23291ba2e6683852655b40658918 664 SUPERFAMILY SSF56801 27 660 1.19E-164 T 12-10-2018 VAPA_2c08530 038e23291ba2e6683852655b40658918 664 TIGRFAM TIGR02188 Ac_CoA_lig_AcsA: acetate--CoA ligase 31 662 8.5E-283 T 12-10-2018 IPR011904 Acetate-CoA ligase GO:0003987|GO:0016208|GO:0019427 KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857|Reactome: R-HSA-71384 VAPA_2c08530 038e23291ba2e6683852655b40658918 664 Gene3D G3DSA:3.40.50.12780 81 534 1.8E-99 T 12-10-2018 VAPA_2c08530 038e23291ba2e6683852655b40658918 664 Gene3D G3DSA:3.30.300.30 535 664 1.6E-27 T 12-10-2018 VAPA_2c08530 038e23291ba2e6683852655b40658918 664 Hamap MF_01123 Acetyl-coenzyme A synthetase [acs]. 12 664 48.965 T 12-10-2018 IPR011904 Acetate-CoA ligase GO:0003987|GO:0016208|GO:0019427 KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857|Reactome: R-HSA-71384 VAPA_2c08530 038e23291ba2e6683852655b40658918 664 Pfam PF00501 AMP-binding enzyme 101 538 3.6E-91 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 VAPA_2c08530 038e23291ba2e6683852655b40658918 664 ProSitePatterns PS00455 Putative AMP-binding domain signature. 270 281 - T 12-10-2018 IPR020845 AMP-binding, conserved site VAPA_1c00260 8bfbb3914d9ffebce6d09ccad3342d9a 479 Pfam PF00512 His Kinase A (phospho-acceptor) domain 260 320 2.1E-12 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 VAPA_1c00260 8bfbb3914d9ffebce6d09ccad3342d9a 479 SMART SM00387 366 477 2.2E-32 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase VAPA_1c00260 8bfbb3914d9ffebce6d09ccad3342d9a 479 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 367 475 2.2E-19 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase VAPA_1c00260 8bfbb3914d9ffebce6d09ccad3342d9a 479 SUPERFAMILY SSF55874 312 476 6.81E-38 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_1c00260 8bfbb3914d9ffebce6d09ccad3342d9a 479 Gene3D G3DSA:3.30.565.10 326 478 4.2E-36 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_1c00260 8bfbb3914d9ffebce6d09ccad3342d9a 479 SUPERFAMILY SSF103190 55 179 7.06E-11 T 12-10-2018 IPR029151 Periplasmic sensor-like domain superfamily VAPA_1c00260 8bfbb3914d9ffebce6d09ccad3342d9a 479 Gene3D G3DSA:1.10.287.130 254 321 5.1E-12 T 12-10-2018 VAPA_1c00260 8bfbb3914d9ffebce6d09ccad3342d9a 479 SUPERFAMILY SSF47384 255 320 1.71E-10 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 VAPA_1c00260 8bfbb3914d9ffebce6d09ccad3342d9a 479 SMART SM00388 255 321 2.1E-13 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 VAPA_1c00260 8bfbb3914d9ffebce6d09ccad3342d9a 479 PRINTS PR00344 Bacterial sensor protein C-terminal signature 403 417 2.4E-9 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c00260 8bfbb3914d9ffebce6d09ccad3342d9a 479 PRINTS PR00344 Bacterial sensor protein C-terminal signature 461 474 2.4E-9 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c00260 8bfbb3914d9ffebce6d09ccad3342d9a 479 PRINTS PR00344 Bacterial sensor protein C-terminal signature 421 431 2.4E-9 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c00260 8bfbb3914d9ffebce6d09ccad3342d9a 479 PRINTS PR00344 Bacterial sensor protein C-terminal signature 437 455 2.4E-9 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_2c10730 21572b1aa9c5de8279b52c3965777ed0 321 SUPERFAMILY SSF53850 109 314 1.58E-50 T 12-10-2018 VAPA_2c10730 21572b1aa9c5de8279b52c3965777ed0 321 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 27 85 1.1E-18 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_2c10730 21572b1aa9c5de8279b52c3965777ed0 321 Gene3D G3DSA:1.10.10.10 24 112 2.0E-25 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_2c10730 21572b1aa9c5de8279b52c3965777ed0 321 Pfam PF03466 LysR substrate binding domain 111 313 2.0E-51 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_2c10730 21572b1aa9c5de8279b52c3965777ed0 321 SUPERFAMILY SSF46785 20 134 2.93E-23 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_2c10730 21572b1aa9c5de8279b52c3965777ed0 321 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 3.0E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_2c10730 21572b1aa9c5de8279b52c3965777ed0 321 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 62 73 3.0E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_2c10730 21572b1aa9c5de8279b52c3965777ed0 321 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 52 62 3.0E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_2c10730 21572b1aa9c5de8279b52c3965777ed0 321 Gene3D G3DSA:3.40.190.290 114 319 9.0E-56 T 12-10-2018 VAPA_2c12250 e1173bb12411195c70bd63bfc15ec101 231 SUPERFAMILY SSF52540 4 221 8.54E-49 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_2c12250 e1173bb12411195c70bd63bfc15ec101 231 Pfam PF00005 ABC transporter 23 161 1.3E-23 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_2c12250 e1173bb12411195c70bd63bfc15ec101 231 SMART SM00382 30 210 6.9E-5 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_2c12250 e1173bb12411195c70bd63bfc15ec101 231 Gene3D G3DSA:3.40.50.300 2 229 8.2E-50 T 12-10-2018 VAPA_1c21440 6e01410ed2e93bc6c5637fd295986ca8 392 Pfam PF00108 Thiolase, N-terminal domain 4 262 9.1E-101 T 12-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 VAPA_1c21440 6e01410ed2e93bc6c5637fd295986ca8 392 Gene3D G3DSA:3.40.47.10 126 389 3.5E-150 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 VAPA_1c21440 6e01410ed2e93bc6c5637fd295986ca8 392 SUPERFAMILY SSF53901 271 392 5.13E-45 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 VAPA_1c21440 6e01410ed2e93bc6c5637fd295986ca8 392 PIRSF PIRSF000429 1 392 3.4E-125 T 12-10-2018 IPR002155 Thiolase GO:0016747 VAPA_1c21440 6e01410ed2e93bc6c5637fd295986ca8 392 Gene3D G3DSA:3.40.47.10 6 276 3.5E-150 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 VAPA_1c21440 6e01410ed2e93bc6c5637fd295986ca8 392 SUPERFAMILY SSF53901 3 270 1.7E-81 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 VAPA_1c21440 6e01410ed2e93bc6c5637fd295986ca8 392 ProSitePatterns PS00737 Thiolases signature 2. 339 355 - T 12-10-2018 IPR020613 Thiolase, conserved site GO:0016747 VAPA_1c21440 6e01410ed2e93bc6c5637fd295986ca8 392 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 391 1.2E-140 T 12-10-2018 IPR002155 Thiolase GO:0016747 VAPA_1c21440 6e01410ed2e93bc6c5637fd295986ca8 392 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 84 102 - T 12-10-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0016747 VAPA_1c21440 6e01410ed2e93bc6c5637fd295986ca8 392 Pfam PF02803 Thiolase, C-terminal domain 270 392 1.3E-52 T 12-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 VAPA_1c21440 6e01410ed2e93bc6c5637fd295986ca8 392 ProSitePatterns PS00099 Thiolases active site. 374 387 - T 12-10-2018 IPR020610 Thiolase, active site GO:0016747 VAPA_1c15030 5ab37ecb3909a7bae45f92f03e50fef0 520 PRINTS PR00982 Lysyl-tRNA synthetase signature 257 270 3.7E-37 T 12-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 VAPA_1c15030 5ab37ecb3909a7bae45f92f03e50fef0 520 PRINTS PR00982 Lysyl-tRNA synthetase signature 212 222 3.7E-37 T 12-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 VAPA_1c15030 5ab37ecb3909a7bae45f92f03e50fef0 520 PRINTS PR00982 Lysyl-tRNA synthetase signature 228 244 3.7E-37 T 12-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 VAPA_1c15030 5ab37ecb3909a7bae45f92f03e50fef0 520 PRINTS PR00982 Lysyl-tRNA synthetase signature 401 417 3.7E-37 T 12-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 VAPA_1c15030 5ab37ecb3909a7bae45f92f03e50fef0 520 PRINTS PR00982 Lysyl-tRNA synthetase signature 275 292 3.7E-37 T 12-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 VAPA_1c15030 5ab37ecb3909a7bae45f92f03e50fef0 520 Pfam PF00152 tRNA synthetases class II (D, K and N) 176 516 1.2E-82 T 12-10-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 VAPA_1c15030 5ab37ecb3909a7bae45f92f03e50fef0 520 SUPERFAMILY SSF50249 23 168 3.64E-39 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold VAPA_1c15030 5ab37ecb3909a7bae45f92f03e50fef0 520 Gene3D G3DSA:2.40.50.140 24 167 9.2E-39 T 12-10-2018 VAPA_1c15030 5ab37ecb3909a7bae45f92f03e50fef0 520 Gene3D G3DSA:3.30.930.10 171 520 3.7E-125 T 12-10-2018 VAPA_1c15030 5ab37ecb3909a7bae45f92f03e50fef0 520 SUPERFAMILY SSF55681 175 517 4.02E-115 T 12-10-2018 VAPA_1c15030 5ab37ecb3909a7bae45f92f03e50fef0 520 Hamap MF_00252 Lysine--tRNA ligase [lysS]. 30 519 43.077 T 12-10-2018 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 VAPA_1c15030 5ab37ecb3909a7bae45f92f03e50fef0 520 TIGRFAM TIGR00499 lysS_bact: lysine--tRNA ligase 25 518 4.7E-196 T 12-10-2018 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 VAPA_1c15030 5ab37ecb3909a7bae45f92f03e50fef0 520 Pfam PF01336 OB-fold nucleic acid binding domain 82 159 1.4E-15 T 12-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 VAPA_2c02650 9602977aa52b335755d1570673a2c84b 310 SUPERFAMILY SSF52283 36 124 1.26E-7 T 12-10-2018 VAPA_2c02650 9602977aa52b335755d1570673a2c84b 310 Gene3D G3DSA:3.40.50.720 94 276 1.5E-106 T 12-10-2018 VAPA_2c02650 9602977aa52b335755d1570673a2c84b 310 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 104 275 2.0E-42 T 12-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 VAPA_2c02650 9602977aa52b335755d1570673a2c84b 310 SUPERFAMILY SSF51735 97 275 3.54E-44 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_2c02650 9602977aa52b335755d1570673a2c84b 310 Gene3D G3DSA:3.40.50.720 17 310 1.5E-106 T 12-10-2018 VAPA_2c10080 806a5a5acb88f8d75795077faa5124ea 97 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 7 77 1.8E-10 T 12-10-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM VAPA_2c10080 806a5a5acb88f8d75795077faa5124ea 97 Gene3D G3DSA:3.40.1620.10 5 45 1.6E-7 T 12-10-2018 VAPA_2c10080 806a5a5acb88f8d75795077faa5124ea 97 SUPERFAMILY SSF143120 7 86 2.75E-9 T 12-10-2018 IPR036165 YefM-like superfamily VAPA_2c02320 068c18b2d2963c71e6b0554dbb4b9fd6 574 ProSitePatterns PS00941 Carboxylesterases type-B signature 2. 135 145 - T 12-10-2018 IPR019819 Carboxylesterase type B, conserved site VAPA_2c02320 068c18b2d2963c71e6b0554dbb4b9fd6 574 SUPERFAMILY SSF53474 57 545 1.2E-92 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_2c02320 068c18b2d2963c71e6b0554dbb4b9fd6 574 Pfam PF00135 Carboxylesterase family 57 546 5.4E-80 T 12-10-2018 IPR002018 Carboxylesterase, type B VAPA_2c02320 068c18b2d2963c71e6b0554dbb4b9fd6 574 Gene3D G3DSA:3.40.50.1820 55 565 2.3E-108 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_2c02320 068c18b2d2963c71e6b0554dbb4b9fd6 574 ProSitePatterns PS00122 Carboxylesterases type-B serine active site. 232 247 - T 12-10-2018 IPR019826 Carboxylesterase type B, active site VAPA_1c20940 ab2c3125d01bf51d41aae2a6e0d86bc4 169 Gene3D G3DSA:3.40.50.2300 5 143 1.2E-40 T 12-10-2018 VAPA_1c20940 ab2c3125d01bf51d41aae2a6e0d86bc4 169 SMART SM00226 6 144 8.5E-33 T 12-10-2018 IPR023485 Phosphotyrosine protein phosphatase I VAPA_1c20940 ab2c3125d01bf51d41aae2a6e0d86bc4 169 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 8 122 2.2E-17 T 12-10-2018 IPR023485 Phosphotyrosine protein phosphatase I VAPA_1c20940 ab2c3125d01bf51d41aae2a6e0d86bc4 169 SUPERFAMILY SSF52788 6 144 1.03E-38 T 12-10-2018 IPR036196 Phosphotyrosine protein phosphatase I superfamily VAPA_1c07810 24a25f41d79313a36519c8d05a0f1d7b 699 TIGRFAM TIGR00595 priA: primosomal protein N' 160 696 2.0E-152 T 12-10-2018 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 VAPA_1c07810 24a25f41d79313a36519c8d05a0f1d7b 699 Hamap MF_00983 Probable primosomal protein N' [priA]. 11 699 21.474 T 12-10-2018 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 VAPA_1c07810 24a25f41d79313a36519c8d05a0f1d7b 699 Gene3D G3DSA:3.40.50.300 129 315 1.4E-64 T 12-10-2018 VAPA_1c07810 24a25f41d79313a36519c8d05a0f1d7b 699 Pfam PF00271 Helicase conserved C-terminal domain 461 544 1.3E-5 T 12-10-2018 IPR001650 Helicase, C-terminal VAPA_1c07810 24a25f41d79313a36519c8d05a0f1d7b 699 Gene3D G3DSA:1.10.8.630 5 117 4.3E-16 T 12-10-2018 VAPA_1c07810 24a25f41d79313a36519c8d05a0f1d7b 699 SMART SM00490 441 546 1.3E-7 T 12-10-2018 IPR001650 Helicase, C-terminal VAPA_1c07810 24a25f41d79313a36519c8d05a0f1d7b 699 SMART SM00487 137 323 2.1E-17 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain VAPA_1c07810 24a25f41d79313a36519c8d05a0f1d7b 699 SUPERFAMILY SSF52540 137 309 1.19E-33 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c07810 24a25f41d79313a36519c8d05a0f1d7b 699 Pfam PF00270 DEAD/DEAH box helicase 145 302 8.2E-14 T 12-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 VAPA_1c07810 24a25f41d79313a36519c8d05a0f1d7b 699 SUPERFAMILY SSF52540 409 547 4.35E-17 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_2c01170 0d6dc12a6e0d0ec6ae3c822988ce97b2 337 SUPERFAMILY SSF46689 283 331 1.03E-12 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 VAPA_2c01170 0d6dc12a6e0d0ec6ae3c822988ce97b2 337 Pfam PF12625 Arabinose-binding domain of AraC transcription regulator, N-term 24 204 8.6E-33 T 12-10-2018 IPR032687 HTH-type transcriptional regulator AraC-type, N-terminal VAPA_2c01170 0d6dc12a6e0d0ec6ae3c822988ce97b2 337 Gene3D G3DSA:1.10.10.60 228 334 2.5E-23 T 12-10-2018 VAPA_2c01170 0d6dc12a6e0d0ec6ae3c822988ce97b2 337 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 299 314 2.3E-6 T 12-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 VAPA_2c01170 0d6dc12a6e0d0ec6ae3c822988ce97b2 337 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 314 330 2.3E-6 T 12-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 VAPA_2c01170 0d6dc12a6e0d0ec6ae3c822988ce97b2 337 Pfam PF12833 Helix-turn-helix domain 257 330 5.2E-16 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 VAPA_2c01170 0d6dc12a6e0d0ec6ae3c822988ce97b2 337 SMART SM00342 247 330 9.0E-24 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 VAPA_1c21810 93a7dc5dbc9ff943bacb09703f25e350 165 PRINTS PR00598 Bacterial regulatory protein MarR family signature 109 125 9.1E-8 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 VAPA_1c21810 93a7dc5dbc9ff943bacb09703f25e350 165 PRINTS PR00598 Bacterial regulatory protein MarR family signature 73 89 9.1E-8 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 VAPA_1c21810 93a7dc5dbc9ff943bacb09703f25e350 165 PRINTS PR00598 Bacterial regulatory protein MarR family signature 90 105 9.1E-8 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 VAPA_1c21810 93a7dc5dbc9ff943bacb09703f25e350 165 SMART SM00347 49 147 5.7E-22 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 VAPA_1c21810 93a7dc5dbc9ff943bacb09703f25e350 165 Gene3D G3DSA:1.10.10.10 7 164 8.5E-35 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c21810 93a7dc5dbc9ff943bacb09703f25e350 165 SUPERFAMILY SSF46785 20 162 2.82E-34 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c21810 93a7dc5dbc9ff943bacb09703f25e350 165 Pfam PF01047 MarR family 56 114 2.9E-15 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 VAPA_1c33160 9fa308176eb08c5da4449ab01334bf12 338 PIRSF PIRSF017082 6 338 3.6E-71 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c33160 9fa308176eb08c5da4449ab01334bf12 338 Gene3D G3DSA:3.40.190.10 140 263 4.3E-100 T 12-10-2018 VAPA_1c33160 9fa308176eb08c5da4449ab01334bf12 338 SUPERFAMILY SSF53850 131 292 2.09E-12 T 12-10-2018 VAPA_1c33160 9fa308176eb08c5da4449ab01334bf12 338 Gene3D G3DSA:3.40.190.150 44 328 4.3E-100 T 12-10-2018 VAPA_1c33160 9fa308176eb08c5da4449ab01334bf12 338 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 62 335 2.4E-80 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c02940 15abd74020046c10783dbef24272a201 267 Gene3D G3DSA:3.90.850.10 1 267 1.4E-78 T 12-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 VAPA_1c02940 15abd74020046c10783dbef24272a201 267 TIGRFAM TIGR02312 HpaH: 2-oxo-hepta-3-ene-1,7-dioic acid hydratase 1 266 8.1E-142 T 12-10-2018 IPR012690 2-oxo-hepta-4-ene-1,7-dioic acid hydratase GO:0018817|GO:0019439 VAPA_1c02940 15abd74020046c10783dbef24272a201 267 SUPERFAMILY SSF56529 3 266 4.71E-77 T 12-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 VAPA_1c02940 15abd74020046c10783dbef24272a201 267 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 90 265 1.2E-6 T 12-10-2018 IPR011234 Fumarylacetoacetase-like, C-terminal GO:0003824 VAPA_1c41900 bcc3ff198b152a34fc2891d461f0134f 339 SUPERFAMILY SSF51197 10 298 4.33E-89 T 12-10-2018 VAPA_1c41900 bcc3ff198b152a34fc2891d461f0134f 339 PRINTS PR00682 Isopenicillin N synthase signature 241 267 2.6E-13 T 12-10-2018 VAPA_1c41900 bcc3ff198b152a34fc2891d461f0134f 339 PRINTS PR00682 Isopenicillin N synthase signature 206 227 2.6E-13 T 12-10-2018 VAPA_1c41900 bcc3ff198b152a34fc2891d461f0134f 339 PRINTS PR00682 Isopenicillin N synthase signature 34 51 2.6E-13 T 12-10-2018 VAPA_1c41900 bcc3ff198b152a34fc2891d461f0134f 339 Pfam PF14226 non-haem dioxygenase in morphine synthesis N-terminal 12 134 3.1E-32 T 12-10-2018 IPR026992 Non-haem dioxygenase N-terminal domain VAPA_1c41900 bcc3ff198b152a34fc2891d461f0134f 339 Gene3D G3DSA:2.60.120.330 6 327 5.5E-92 T 12-10-2018 IPR027443 Isopenicillin N synthase-like VAPA_1c41900 bcc3ff198b152a34fc2891d461f0134f 339 Pfam PF03171 2OG-Fe(II) oxygenase superfamily 185 281 3.0E-24 T 12-10-2018 IPR005123 Oxoglutarate/iron-dependent dioxygenase GO:0016491|GO:0055114 VAPA_1c10080 d5a7ecfd4e8dc3a4a4bf65f7ea8e4245 971 Pfam PF03477 ATP cone domain 38 134 2.0E-15 T 12-10-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 VAPA_1c10080 d5a7ecfd4e8dc3a4a4bf65f7ea8e4245 971 SUPERFAMILY SSF51998 368 908 5.8E-179 T 12-10-2018 VAPA_1c10080 d5a7ecfd4e8dc3a4a4bf65f7ea8e4245 971 Gene3D G3DSA:3.20.70.20 224 914 6.2E-245 T 12-10-2018 VAPA_1c10080 d5a7ecfd4e8dc3a4a4bf65f7ea8e4245 971 SUPERFAMILY SSF48168 156 367 4.58E-61 T 12-10-2018 IPR008926 Ribonucleotide reductase R1 subunit, N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 VAPA_1c10080 d5a7ecfd4e8dc3a4a4bf65f7ea8e4245 971 Pfam PF02867 Ribonucleotide reductase, barrel domain 369 903 6.1E-181 T 12-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 VAPA_1c10080 d5a7ecfd4e8dc3a4a4bf65f7ea8e4245 971 ProSitePatterns PS00089 Ribonucleotide reductase large subunit signature. 747 769 - T 12-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 VAPA_1c10080 d5a7ecfd4e8dc3a4a4bf65f7ea8e4245 971 TIGRFAM TIGR02506 NrdE_NrdA: ribonucleoside-diphosphate reductase, alpha subunit 295 907 5.1E-215 T 12-10-2018 IPR013346 Ribonucleotide reductase, class I , alpha subunit GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 VAPA_1c10080 d5a7ecfd4e8dc3a4a4bf65f7ea8e4245 971 Pfam PF00317 Ribonucleotide reductase, all-alpha domain 292 363 3.8E-21 T 12-10-2018 IPR013509 Ribonucleotide reductase large subunit, N-terminal GO:0004748|GO:0005524|GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 VAPA_1c10080 d5a7ecfd4e8dc3a4a4bf65f7ea8e4245 971 PRINTS PR01183 Ribonucleotide reductase large chain signature 682 705 5.0E-44 T 12-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 VAPA_1c10080 d5a7ecfd4e8dc3a4a4bf65f7ea8e4245 971 PRINTS PR01183 Ribonucleotide reductase large chain signature 444 463 5.0E-44 T 12-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 VAPA_1c10080 d5a7ecfd4e8dc3a4a4bf65f7ea8e4245 971 PRINTS PR01183 Ribonucleotide reductase large chain signature 654 676 5.0E-44 T 12-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 VAPA_1c10080 d5a7ecfd4e8dc3a4a4bf65f7ea8e4245 971 PRINTS PR01183 Ribonucleotide reductase large chain signature 579 590 5.0E-44 T 12-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 VAPA_1c10080 d5a7ecfd4e8dc3a4a4bf65f7ea8e4245 971 PRINTS PR01183 Ribonucleotide reductase large chain signature 758 785 5.0E-44 T 12-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 VAPA_1c10080 d5a7ecfd4e8dc3a4a4bf65f7ea8e4245 971 PRINTS PR01183 Ribonucleotide reductase large chain signature 616 639 5.0E-44 T 12-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 VAPA_1c40440 8dbff6acc50f30bbae2867fc406fd68b 446 SUPERFAMILY SSF82544 18 445 3.4E-145 T 12-10-2018 VAPA_1c40440 8dbff6acc50f30bbae2867fc406fd68b 446 Gene3D G3DSA:3.40.50.10180 47 272 4.2E-137 T 12-10-2018 IPR038614 Glycerate kinase, N-terminal domain superfamily Reactome: R-HSA-70350 VAPA_1c40440 8dbff6acc50f30bbae2867fc406fd68b 446 Pfam PF05161 MOFRL family 328 439 3.2E-33 T 12-10-2018 IPR007835 MOFRL domain Reactome: R-HSA-70350 VAPA_1c40440 8dbff6acc50f30bbae2867fc406fd68b 446 Pfam PF13660 Domain of unknown function (DUF4147) 23 249 5.2E-78 T 12-10-2018 IPR025286 MOFRL-associated domain Reactome: R-HSA-70350 VAPA_1c40440 8dbff6acc50f30bbae2867fc406fd68b 446 Gene3D G3DSA:3.40.1480.10 273 440 4.2E-137 T 12-10-2018 IPR037035 Glycerate kinase-like, C-terminal domain superfamily VAPA_2c05240 634e194c500b06db834485541f5b74e7 332 Pfam PF09084 NMT1/THI5 like 45 253 3.7E-15 T 12-10-2018 IPR015168 SsuA/THI5-like VAPA_2c05240 634e194c500b06db834485541f5b74e7 332 Gene3D G3DSA:3.40.190.10 108 209 2.9E-39 T 12-10-2018 VAPA_2c05240 634e194c500b06db834485541f5b74e7 332 Gene3D G3DSA:3.40.190.10 50 313 2.9E-39 T 12-10-2018 VAPA_2c05240 634e194c500b06db834485541f5b74e7 332 SMART SM00062 30 243 0.002 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF VAPA_2c05240 634e194c500b06db834485541f5b74e7 332 SUPERFAMILY SSF53850 29 254 5.12E-37 T 12-10-2018 VAPA_2c05240 634e194c500b06db834485541f5b74e7 332 Gene3D G3DSA:1.10.8.450 244 284 2.9E-39 T 12-10-2018 VAPA_2c09120 e509299d22b967adc7a8f1aef6190067 198 Pfam PF02566 OsmC-like protein 80 174 4.5E-18 T 12-10-2018 IPR003718 OsmC/Ohr family VAPA_2c09120 e509299d22b967adc7a8f1aef6190067 198 TIGRFAM TIGR03561 organ_hyd_perox: peroxiredoxin, Ohr subfamily 51 175 5.8E-36 T 12-10-2018 IPR019953 Organic hydroperoxide resistance protein famiy GO:0006979 VAPA_2c09120 e509299d22b967adc7a8f1aef6190067 198 Gene3D G3DSA:3.30.300.20 86 179 2.0E-24 T 12-10-2018 IPR015946 K homology domain-like, alpha/beta VAPA_2c09120 e509299d22b967adc7a8f1aef6190067 198 SUPERFAMILY SSF82784 37 174 9.95E-33 T 12-10-2018 IPR036102 OsmC/Ohr superfamily VAPA_2c09120 e509299d22b967adc7a8f1aef6190067 198 Gene3D G3DSA:2.20.25.10 35 85 5.8E-7 T 12-10-2018 VAPA_1c34540 b176d55700d60d638398853e38fdd54f 395 SUPERFAMILY SSF54826 50 154 1.31E-25 T 12-10-2018 VAPA_1c34540 b176d55700d60d638398853e38fdd54f 395 Pfam PF13378 Enolase C-terminal domain-like 176 386 9.4E-41 T 12-10-2018 IPR029065 Enolase C-terminal domain-like VAPA_1c34540 b176d55700d60d638398853e38fdd54f 395 ProSitePatterns PS00908 Mandelate racemase / muconate lactonizing enzyme family signature 1. 124 149 - T 12-10-2018 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 VAPA_1c34540 b176d55700d60d638398853e38fdd54f 395 SUPERFAMILY SSF51604 137 392 3.41E-55 T 12-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily VAPA_1c34540 b176d55700d60d638398853e38fdd54f 395 SMART SM00922 160 262 2.5E-8 T 12-10-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal VAPA_1c34540 b176d55700d60d638398853e38fdd54f 395 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 59 149 2.0E-10 T 12-10-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain VAPA_1c34540 b176d55700d60d638398853e38fdd54f 395 Hamap MF_01288 L-rhamnonate dehydratase [rhmD]. 1 395 79.735 T 12-10-2018 IPR023444 L-rhamnonate dehydratase GO:0050032 KEGG: 00051+4.2.1.90|MetaCyc: PWY-6713|MetaCyc: PWY-6714 VAPA_1c34540 b176d55700d60d638398853e38fdd54f 395 Gene3D G3DSA:3.30.390.10 2 148 5.8E-206 T 12-10-2018 IPR029017 Enolase-like, N-terminal VAPA_1c34540 b176d55700d60d638398853e38fdd54f 395 Gene3D G3DSA:3.20.20.120 149 387 5.8E-206 T 12-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily VAPA_1c11680 fb616413d30a4b61b48be46bc59b749f 466 Pfam PF01232 Mannitol dehydrogenase Rossmann domain 2 172 3.0E-34 T 12-10-2018 IPR013131 Mannitol dehydrogenase, N-terminal GO:0016491|GO:0055114 VAPA_1c11680 fb616413d30a4b61b48be46bc59b749f 466 SUPERFAMILY SSF51735 2 266 2.01E-74 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c11680 fb616413d30a4b61b48be46bc59b749f 466 SUPERFAMILY SSF48179 269 452 1.67E-46 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 VAPA_1c11680 fb616413d30a4b61b48be46bc59b749f 466 PRINTS PR00084 Mannitol dehydrogenase signature 2 12 1.6E-16 T 12-10-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 VAPA_1c11680 fb616413d30a4b61b48be46bc59b749f 466 PRINTS PR00084 Mannitol dehydrogenase signature 203 216 1.6E-16 T 12-10-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 VAPA_1c11680 fb616413d30a4b61b48be46bc59b749f 466 PRINTS PR00084 Mannitol dehydrogenase signature 163 176 1.6E-16 T 12-10-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 VAPA_1c11680 fb616413d30a4b61b48be46bc59b749f 466 PRINTS PR00084 Mannitol dehydrogenase signature 233 248 1.6E-16 T 12-10-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 VAPA_1c11680 fb616413d30a4b61b48be46bc59b749f 466 Gene3D G3DSA:1.10.1040.10 267 461 4.9E-49 T 12-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 VAPA_1c11680 fb616413d30a4b61b48be46bc59b749f 466 Pfam PF08125 Mannitol dehydrogenase C-terminal domain 202 430 3.9E-74 T 12-10-2018 IPR013118 Mannitol dehydrogenase, C-terminal GO:0016491|GO:0050662|GO:0055114 VAPA_1c11680 fb616413d30a4b61b48be46bc59b749f 466 Gene3D G3DSA:3.40.50.720 1 266 1.4E-82 T 12-10-2018 VAPA_1c18600 b5d910464599d360cf60757647d80905 328 Gene3D G3DSA:3.40.50.720 99 289 4.9E-113 T 12-10-2018 VAPA_1c18600 b5d910464599d360cf60757647d80905 328 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 6 320 7.7E-26 T 12-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 VAPA_1c18600 b5d910464599d360cf60757647d80905 328 SUPERFAMILY SSF51735 102 290 2.23E-58 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c18600 b5d910464599d360cf60757647d80905 328 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 150 178 - T 12-10-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 VAPA_1c18600 b5d910464599d360cf60757647d80905 328 SUPERFAMILY SSF52283 3 136 2.1E-34 T 12-10-2018 VAPA_1c18600 b5d910464599d360cf60757647d80905 328 Gene3D G3DSA:3.40.50.720 5 314 4.9E-113 T 12-10-2018 VAPA_1c18600 b5d910464599d360cf60757647d80905 328 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 110 289 1.4E-57 T 12-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 VAPA_1c53560 42f3f7dda2a07a350f397d69f68332fd 209 PIRSF PIRSF000303 32 208 1.1E-57 T 12-10-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 VAPA_1c53560 42f3f7dda2a07a350f397d69f68332fd 209 Gene3D G3DSA:3.40.30.10 45 207 5.2E-50 T 12-10-2018 VAPA_1c53560 42f3f7dda2a07a350f397d69f68332fd 209 PRINTS PR01011 Glutathione peroxidase family signature 107 123 6.8E-13 T 12-10-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 VAPA_1c53560 42f3f7dda2a07a350f397d69f68332fd 209 PRINTS PR01011 Glutathione peroxidase family signature 72 89 6.8E-13 T 12-10-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 VAPA_1c53560 42f3f7dda2a07a350f397d69f68332fd 209 PRINTS PR01011 Glutathione peroxidase family signature 167 176 6.8E-13 T 12-10-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 VAPA_1c53560 42f3f7dda2a07a350f397d69f68332fd 209 ProSitePatterns PS00460 Glutathione peroxidases active site. 74 89 - T 12-10-2018 IPR029759 Glutathione peroxidase active site Reactome: R-HSA-3299685 VAPA_1c53560 42f3f7dda2a07a350f397d69f68332fd 209 SUPERFAMILY SSF52833 54 205 2.48E-50 T 12-10-2018 IPR036249 Thioredoxin-like superfamily VAPA_1c53560 42f3f7dda2a07a350f397d69f68332fd 209 Pfam PF00255 Glutathione peroxidase 62 159 2.9E-31 T 12-10-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 VAPA_1c33640 38eb7fd88874447527f12c921c70d27e 384 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 116 1.6E-26 T 12-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 VAPA_1c33640 38eb7fd88874447527f12c921c70d27e 384 SUPERFAMILY SSF56645 1 240 4.19E-80 T 12-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 VAPA_1c33640 38eb7fd88874447527f12c921c70d27e 384 SUPERFAMILY SSF47203 225 379 4.35E-59 T 12-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 VAPA_1c33640 38eb7fd88874447527f12c921c70d27e 384 Gene3D G3DSA:1.10.540.10 1 119 6.0E-33 T 12-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 VAPA_1c33640 38eb7fd88874447527f12c921c70d27e 384 Gene3D G3DSA:1.20.140.10 232 381 2.8E-55 T 12-10-2018 VAPA_1c33640 38eb7fd88874447527f12c921c70d27e 384 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 335 354 - T 12-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 VAPA_1c33640 38eb7fd88874447527f12c921c70d27e 384 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 121 215 6.5E-25 T 12-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 VAPA_1c33640 38eb7fd88874447527f12c921c70d27e 384 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 227 376 6.3E-48 T 12-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 VAPA_1c33640 38eb7fd88874447527f12c921c70d27e 384 Gene3D G3DSA:2.40.110.10 120 231 1.7E-43 T 12-10-2018 VAPA_1c33640 38eb7fd88874447527f12c921c70d27e 384 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 123 135 - T 12-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 VAPA_1c33640 38eb7fd88874447527f12c921c70d27e 384 PIRSF PIRSF016578 3 382 9.2E-20 T 12-10-2018 VAPA_1c08160 bf3827c5be2de9061f6228d8c458b7ce 298 Pfam PF00483 Nucleotidyl transferase 8 244 8.4E-70 T 12-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 VAPA_1c08160 bf3827c5be2de9061f6228d8c458b7ce 298 TIGRFAM TIGR01207 rmlA: glucose-1-phosphate thymidylyltransferase 8 292 7.0E-156 T 12-10-2018 IPR005907 Glucose-1-phosphate thymidylyltransferase, short form GO:0008879|GO:0045226 KEGG: 00521+2.7.7.24|KEGG: 00523+2.7.7.24|KEGG: 00525+2.7.7.24|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688|MetaCyc: PWY-7814 VAPA_1c08160 bf3827c5be2de9061f6228d8c458b7ce 298 SUPERFAMILY SSF53448 7 292 2.7E-90 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases VAPA_1c08160 bf3827c5be2de9061f6228d8c458b7ce 298 Gene3D G3DSA:3.90.550.10 1 297 1.9E-85 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases VAPA_2c00700 bf3827c5be2de9061f6228d8c458b7ce 298 Pfam PF00483 Nucleotidyl transferase 8 244 8.4E-70 T 12-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 VAPA_2c00700 bf3827c5be2de9061f6228d8c458b7ce 298 TIGRFAM TIGR01207 rmlA: glucose-1-phosphate thymidylyltransferase 8 292 7.0E-156 T 12-10-2018 IPR005907 Glucose-1-phosphate thymidylyltransferase, short form GO:0008879|GO:0045226 KEGG: 00521+2.7.7.24|KEGG: 00523+2.7.7.24|KEGG: 00525+2.7.7.24|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688|MetaCyc: PWY-7814 VAPA_2c00700 bf3827c5be2de9061f6228d8c458b7ce 298 SUPERFAMILY SSF53448 7 292 2.7E-90 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases VAPA_2c00700 bf3827c5be2de9061f6228d8c458b7ce 298 Gene3D G3DSA:3.90.550.10 1 297 1.9E-85 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases VAPA_1c54990 bd89ae86ed307d5f9fd67fc17a46507e 390 Gene3D G3DSA:3.40.50.1820 20 364 9.7E-136 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c54990 bd89ae86ed307d5f9fd67fc17a46507e 390 Pfam PF00561 alpha/beta hydrolase fold 45 364 9.9E-35 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 VAPA_1c54990 bd89ae86ed307d5f9fd67fc17a46507e 390 TIGRFAM TIGR01392 homoserO_Ac_trn: homoserine O-acetyltransferase 16 375 2.7E-135 T 12-10-2018 IPR008220 Homoserine/serine acetyltransferase MetX-like GO:0005737|GO:0009058|GO:0016747 VAPA_1c54990 bd89ae86ed307d5f9fd67fc17a46507e 390 Hamap MF_00296 Homoserine O-acetyltransferase [metXA]. 2 377 29.854 T 12-10-2018 IPR008220 Homoserine/serine acetyltransferase MetX-like GO:0005737|GO:0009058|GO:0016747 VAPA_1c54990 bd89ae86ed307d5f9fd67fc17a46507e 390 SUPERFAMILY SSF53474 9 378 4.45E-104 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c54990 bd89ae86ed307d5f9fd67fc17a46507e 390 PIRSF PIRSF000443 1 387 1.8E-138 T 12-10-2018 IPR008220 Homoserine/serine acetyltransferase MetX-like GO:0005737|GO:0009058|GO:0016747 VAPA_1c54990 bd89ae86ed307d5f9fd67fc17a46507e 390 Gene3D G3DSA:1.10.1740.110 181 295 9.7E-136 T 12-10-2018 VAPA_1c46130 9e0d06339943731a8f359b08c5b80afc 338 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 62 331 1.4E-55 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c46130 9e0d06339943731a8f359b08c5b80afc 338 SUPERFAMILY SSF53850 100 299 1.06E-10 T 12-10-2018 VAPA_1c46130 9e0d06339943731a8f359b08c5b80afc 338 Gene3D G3DSA:3.40.190.10 139 262 3.8E-84 T 12-10-2018 VAPA_1c46130 9e0d06339943731a8f359b08c5b80afc 338 PIRSF PIRSF017082 4 336 3.6E-56 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c46130 9e0d06339943731a8f359b08c5b80afc 338 Gene3D G3DSA:3.40.190.150 42 326 3.8E-84 T 12-10-2018 VAPA_1c50940 d43e1375b2a03fc60e799aa2b7671bec 206 TIGRFAM TIGR03953 rplD_bact: 50S ribosomal protein uL4 19 203 8.0E-66 T 12-10-2018 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 VAPA_1c50940 d43e1375b2a03fc60e799aa2b7671bec 206 SUPERFAMILY SSF52166 1 205 2.09E-66 T 12-10-2018 IPR023574 Ribosomal protein L4 domain superfamily GO:0003735|GO:0005840|GO:0006412 VAPA_1c50940 d43e1375b2a03fc60e799aa2b7671bec 206 Pfam PF00573 Ribosomal protein L4/L1 family 19 203 4.7E-58 T 12-10-2018 IPR002136 Ribosomal protein L4/L1e GO:0003735|GO:0005840|GO:0006412 VAPA_1c50940 d43e1375b2a03fc60e799aa2b7671bec 206 Gene3D G3DSA:3.40.1370.10 2 206 5.3E-62 T 12-10-2018 IPR023574 Ribosomal protein L4 domain superfamily GO:0003735|GO:0005840|GO:0006412 VAPA_1c50940 d43e1375b2a03fc60e799aa2b7671bec 206 Hamap MF_01328_B 50S ribosomal protein L4 [rplD]. 8 206 30.53 T 12-10-2018 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 VAPA_2c01980 aade82d5d134467cae8226821fb96f20 649 Gene3D G3DSA:3.40.50.300 328 512 2.8E-59 T 12-10-2018 VAPA_2c01980 aade82d5d134467cae8226821fb96f20 649 SUPERFAMILY SSF55781 68 213 1.54E-7 T 12-10-2018 VAPA_2c01980 aade82d5d134467cae8226821fb96f20 649 Gene3D G3DSA:1.10.10.60 592 648 2.1E-13 T 12-10-2018 VAPA_2c01980 aade82d5d134467cae8226821fb96f20 649 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 427 442 - T 12-10-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 VAPA_2c01980 aade82d5d134467cae8226821fb96f20 649 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 629 649 9.2E-8 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 VAPA_2c01980 aade82d5d134467cae8226821fb96f20 649 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 612 629 9.2E-8 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 VAPA_2c01980 aade82d5d134467cae8226821fb96f20 649 Gene3D G3DSA:1.10.8.60 514 587 5.1E-8 T 12-10-2018 VAPA_2c01980 aade82d5d134467cae8226821fb96f20 649 Pfam PF00158 Sigma-54 interaction domain 344 507 9.4E-63 T 12-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 VAPA_2c01980 aade82d5d134467cae8226821fb96f20 649 Gene3D G3DSA:3.30.450.40 29 215 1.6E-54 T 12-10-2018 IPR029016 GAF-like domain superfamily VAPA_2c01980 aade82d5d134467cae8226821fb96f20 649 SUPERFAMILY SSF46689 550 646 1.49E-10 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 VAPA_2c01980 aade82d5d134467cae8226821fb96f20 649 SUPERFAMILY SSF52540 344 572 1.55E-57 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_2c01980 aade82d5d134467cae8226821fb96f20 649 Pfam PF01590 GAF domain 84 212 1.4E-8 T 12-10-2018 IPR003018 GAF domain GO:0005515 VAPA_2c01980 aade82d5d134467cae8226821fb96f20 649 Pfam PF02954 Bacterial regulatory protein, Fis family 615 646 9.0E-12 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 VAPA_2c01980 aade82d5d134467cae8226821fb96f20 649 SMART SM00382 360 504 1.0E-10 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c53900 74ea5004bf52cb3ac13fef54dc8c909c 434 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 205 293 1.5E-23 T 12-10-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 VAPA_1c53900 74ea5004bf52cb3ac13fef54dc8c909c 434 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 10 405 4.6E-113 T 12-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 VAPA_1c53900 74ea5004bf52cb3ac13fef54dc8c909c 434 SUPERFAMILY SSF48179 204 295 4.93E-25 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 VAPA_1c53900 74ea5004bf52cb3ac13fef54dc8c909c 434 SUPERFAMILY SSF52413 305 432 1.83E-28 T 12-10-2018 IPR036220 UDP-glucose/GDP-mannose dehydrogenase, C-terminal domain superfamily Reactome: R-HSA-173599 VAPA_1c53900 74ea5004bf52cb3ac13fef54dc8c909c 434 Gene3D G3DSA:3.40.50.720 2 200 5.9E-55 T 12-10-2018 VAPA_1c53900 74ea5004bf52cb3ac13fef54dc8c909c 434 PIRSF PIRSF000124 9 434 9.2E-53 T 12-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 VAPA_1c53900 74ea5004bf52cb3ac13fef54dc8c909c 434 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 10 182 2.4E-30 T 12-10-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 VAPA_1c53900 74ea5004bf52cb3ac13fef54dc8c909c 434 SMART SM00984 320 421 3.5E-34 T 12-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 VAPA_1c53900 74ea5004bf52cb3ac13fef54dc8c909c 434 SUPERFAMILY SSF51735 10 194 2.12E-41 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c53900 74ea5004bf52cb3ac13fef54dc8c909c 434 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 321 421 9.0E-21 T 12-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 VAPA_1c53900 74ea5004bf52cb3ac13fef54dc8c909c 434 Gene3D G3DSA:3.40.50.720 204 434 2.5E-60 T 12-10-2018 VAPA_1c53900 74ea5004bf52cb3ac13fef54dc8c909c 434 PIRSF PIRSF500136 2 434 3.0E-140 T 12-10-2018 IPR028359 UDP-N-acetyl-D-mannosamine/glucosamine dehydrogenase GO:0000271|GO:0016628|GO:0055114 VAPA_1c46970 9c77c44c4d033a0a7ecd3b9e574c1fe9 207 Pfam PF00589 Phage integrase family 40 191 3.2E-16 T 12-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 VAPA_1c46970 9c77c44c4d033a0a7ecd3b9e574c1fe9 207 SUPERFAMILY SSF56349 20 205 2.47E-36 T 12-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 VAPA_1c46970 9c77c44c4d033a0a7ecd3b9e574c1fe9 207 Gene3D G3DSA:1.10.443.10 21 193 7.4E-25 T 12-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 VAPA_1c03090 3fe9c115f034499a936f14a7842c374e 403 Gene3D G3DSA:3.30.70.360 194 308 1.8E-127 T 12-10-2018 VAPA_1c03090 3fe9c115f034499a936f14a7842c374e 403 Pfam PF07687 Peptidase dimerisation domain 200 290 5.1E-11 T 12-10-2018 IPR011650 Peptidase M20, dimerisation domain VAPA_1c03090 3fe9c115f034499a936f14a7842c374e 403 Pfam PF01546 Peptidase family M20/M25/M40 86 398 5.5E-34 T 12-10-2018 IPR002933 Peptidase M20 GO:0016787 VAPA_1c03090 3fe9c115f034499a936f14a7842c374e 403 Gene3D G3DSA:3.40.630.10 28 386 1.8E-127 T 12-10-2018 VAPA_1c03090 3fe9c115f034499a936f14a7842c374e 403 PIRSF PIRSF005962 12 402 1.5E-115 T 12-10-2018 IPR017439 Amidohydrolase GO:0016787 VAPA_1c03090 3fe9c115f034499a936f14a7842c374e 403 SUPERFAMILY SSF53187 17 401 1.29E-83 T 12-10-2018 VAPA_1c03090 3fe9c115f034499a936f14a7842c374e 403 SUPERFAMILY SSF55031 197 304 7.07E-31 T 12-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain VAPA_1c03090 3fe9c115f034499a936f14a7842c374e 403 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 28 389 2.0E-101 T 12-10-2018 IPR017439 Amidohydrolase GO:0016787 VAPA_1c21140 9e4d5fa9fbaef3e564b68d569d2f8480 612 Gene3D G3DSA:3.20.20.80 110 527 1.1E-175 T 12-10-2018 VAPA_1c21140 9e4d5fa9fbaef3e564b68d569d2f8480 612 Pfam PF11941 Domain of unknown function (DUF3459) 519 598 4.9E-10 T 12-10-2018 IPR022567 Glycosyl hydrolase, C-terminal (DUF3459) VAPA_1c21140 9e4d5fa9fbaef3e564b68d569d2f8480 612 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 10 74 1.2E-5 T 12-10-2018 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 VAPA_1c21140 9e4d5fa9fbaef3e564b68d569d2f8480 612 Gene3D G3DSA:1.10.10.760 455 499 1.1E-175 T 12-10-2018 VAPA_1c21140 9e4d5fa9fbaef3e564b68d569d2f8480 612 SUPERFAMILY SSF81296 11 101 1.32E-16 T 12-10-2018 IPR014756 Immunoglobulin E-set VAPA_1c21140 9e4d5fa9fbaef3e564b68d569d2f8480 612 PIRSF PIRSF006337 7 605 2.6E-218 T 12-10-2018 IPR012768 Malto-oligosyltrehalose trehalohydrolase GO:0004553|GO:0005992 KEGG: 00500+3.2.1.141|MetaCyc: PWY-2661 VAPA_1c21140 9e4d5fa9fbaef3e564b68d569d2f8480 612 TIGRFAM TIGR02402 trehalose_TreZ: malto-oligosyltrehalose trehalohydrolase 21 571 1.6E-212 T 12-10-2018 IPR012768 Malto-oligosyltrehalose trehalohydrolase GO:0004553|GO:0005992 KEGG: 00500+3.2.1.141|MetaCyc: PWY-2661 VAPA_1c21140 9e4d5fa9fbaef3e564b68d569d2f8480 612 SUPERFAMILY SSF51445 97 528 1.06E-105 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily VAPA_1c21140 9e4d5fa9fbaef3e564b68d569d2f8480 612 Gene3D G3DSA:2.60.40.10 8 106 6.3E-23 T 12-10-2018 IPR013783 Immunoglobulin-like fold VAPA_1c21140 9e4d5fa9fbaef3e564b68d569d2f8480 612 SMART SM00642 96 469 6.6E-9 T 12-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 VAPA_1c21140 9e4d5fa9fbaef3e564b68d569d2f8480 612 Pfam PF00128 Alpha amylase, catalytic domain 132 216 1.9E-12 T 12-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 VAPA_1c52560 6e62beb088f7a54157ccf84950ee90bb 191 Gene3D G3DSA:1.20.1260.10 22 191 5.3E-57 T 12-10-2018 IPR012347 Ferritin-like VAPA_1c52560 6e62beb088f7a54157ccf84950ee90bb 191 SUPERFAMILY SSF47240 36 191 3.81E-49 T 12-10-2018 IPR009078 Ferritin-like superfamily VAPA_1c52560 6e62beb088f7a54157ccf84950ee90bb 191 PIRSF PIRSF005900 29 191 1.4E-43 T 12-10-2018 IPR002177 DNA-binding protein Dps VAPA_1c52560 6e62beb088f7a54157ccf84950ee90bb 191 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 95 111 3.2E-9 T 12-10-2018 IPR002177 DNA-binding protein Dps VAPA_1c52560 6e62beb088f7a54157ccf84950ee90bb 191 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 167 185 3.2E-9 T 12-10-2018 IPR002177 DNA-binding protein Dps VAPA_1c52560 6e62beb088f7a54157ccf84950ee90bb 191 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 71 87 3.2E-9 T 12-10-2018 IPR002177 DNA-binding protein Dps VAPA_1c52560 6e62beb088f7a54157ccf84950ee90bb 191 Pfam PF00210 Ferritin-like domain 51 191 5.6E-30 T 12-10-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 VAPA_1c42880 fc02720cdd97ecd3017b20ef9451092c 410 Gene3D G3DSA:3.40.50.720 15 313 7.1E-104 T 12-10-2018 VAPA_1c42880 fc02720cdd97ecd3017b20ef9451092c 410 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 230 246 - T 12-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site VAPA_1c42880 fc02720cdd97ecd3017b20ef9451092c 410 SUPERFAMILY SSF55021 333 409 3.44E-17 T 12-10-2018 VAPA_1c42880 fc02720cdd97ecd3017b20ef9451092c 410 Gene3D G3DSA:3.40.50.720 110 298 7.1E-104 T 12-10-2018 VAPA_1c42880 fc02720cdd97ecd3017b20ef9451092c 410 SUPERFAMILY SSF51735 109 296 3.47E-54 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c42880 fc02720cdd97ecd3017b20ef9451092c 410 Gene3D G3DSA:3.30.70.260 329 409 1.6E-32 T 12-10-2018 VAPA_1c42880 fc02720cdd97ecd3017b20ef9451092c 410 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 201 223 - T 12-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site VAPA_1c42880 fc02720cdd97ecd3017b20ef9451092c 410 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 15 327 1.7E-34 T 12-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 VAPA_1c42880 fc02720cdd97ecd3017b20ef9451092c 410 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 120 295 1.4E-49 T 12-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 VAPA_1c42880 fc02720cdd97ecd3017b20ef9451092c 410 SUPERFAMILY SSF52283 8 133 3.83E-46 T 12-10-2018 VAPA_1c15890 c34976aa30ab7a6735a44b635537d3b5 417 Gene3D G3DSA:3.40.50.720 171 392 5.7E-35 T 12-10-2018 VAPA_1c15890 c34976aa30ab7a6735a44b635537d3b5 417 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 323 342 4.6E-11 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c15890 c34976aa30ab7a6735a44b635537d3b5 417 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 344 361 4.6E-11 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c15890 c34976aa30ab7a6735a44b635537d3b5 417 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 171 188 4.6E-11 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c15890 c34976aa30ab7a6735a44b635537d3b5 417 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 243 254 4.6E-11 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c15890 c34976aa30ab7a6735a44b635537d3b5 417 SUPERFAMILY SSF50249 37 135 1.56E-21 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold VAPA_1c15890 c34976aa30ab7a6735a44b635537d3b5 417 Pfam PF00106 short chain dehydrogenase 171 363 7.9E-23 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c15890 c34976aa30ab7a6735a44b635537d3b5 417 SUPERFAMILY SSF51735 169 386 3.15E-35 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c15890 c34976aa30ab7a6735a44b635537d3b5 417 Pfam PF01796 DUF35 OB-fold domain, acyl-CoA-associated 72 135 2.9E-11 T 12-10-2018 IPR002878 Domain of unknown function DUF35, OB-fold, C-terminal VAPA_1c15890 c34976aa30ab7a6735a44b635537d3b5 417 Pfam PF12172 Rubredoxin-like zinc ribbon domain (DUF35_N) 36 70 6.1E-13 T 12-10-2018 IPR022002 Domain of unknown function DUF35, rubredoxin-like zinc ribbon domain, N-terminal VAPA_1c30690 e9ba3cf8f132c6b9e79e5192949dba93 498 SUPERFAMILY SSF56954 3 478 1.07E-91 T 12-10-2018 VAPA_1c30690 e9ba3cf8f132c6b9e79e5192949dba93 498 Pfam PF02321 Outer membrane efflux protein 292 475 6.6E-29 T 12-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 VAPA_1c30690 e9ba3cf8f132c6b9e79e5192949dba93 498 Pfam PF02321 Outer membrane efflux protein 66 264 7.2E-19 T 12-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 VAPA_1c30690 e9ba3cf8f132c6b9e79e5192949dba93 498 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 17 477 1.1E-95 T 12-10-2018 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0016020|GO:0022857|GO:0055085 VAPA_1c30690 e9ba3cf8f132c6b9e79e5192949dba93 498 Gene3D G3DSA:1.20.1600.10 55 478 1.0E-105 T 12-10-2018 VAPA_1c30690 e9ba3cf8f132c6b9e79e5192949dba93 498 Gene3D G3DSA:2.20.200.10 102 366 1.0E-105 T 12-10-2018 VAPA_2c09830 48639b1ed5cbb88c3bf855cee799605e 259 Gene3D G3DSA:3.30.450.40 82 258 1.4E-25 T 12-10-2018 IPR029016 GAF-like domain superfamily VAPA_2c09830 48639b1ed5cbb88c3bf855cee799605e 259 Gene3D G3DSA:1.10.10.10 1 79 1.3E-17 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_2c09830 48639b1ed5cbb88c3bf855cee799605e 259 SUPERFAMILY SSF55781 70 257 2.29E-29 T 12-10-2018 VAPA_2c09830 48639b1ed5cbb88c3bf855cee799605e 259 Pfam PF09339 IclR helix-turn-helix domain 18 65 1.4E-10 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 VAPA_2c09830 48639b1ed5cbb88c3bf855cee799605e 259 SUPERFAMILY SSF46785 14 85 1.5E-10 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_2c09830 48639b1ed5cbb88c3bf855cee799605e 259 SMART SM00346 12 102 7.2E-15 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 VAPA_2c09830 48639b1ed5cbb88c3bf855cee799605e 259 Pfam PF01614 Bacterial transcriptional regulator 135 253 2.9E-5 T 12-10-2018 IPR014757 Transcription regulator IclR, C-terminal VAPA_1c21950 98f1dc996370ac656c712f95969319c6 126 Pfam PF12903 Protein of unknown function (DUF3830) 9 124 9.2E-30 T 12-10-2018 IPR024532 Protein of unknown function DUF3830 VAPA_1c21950 98f1dc996370ac656c712f95969319c6 126 Gene3D G3DSA:2.40.100.20 2 126 3.7E-37 T 12-10-2018 VAPA_1c17800 f1a010997cbe6ae7d1ae2ca5593f6f65 201 PIRSF PIRSF006707 1 176 3.3E-65 T 12-10-2018 IPR026282 DNA-binding protein, MJ1563 type VAPA_1c17800 f1a010997cbe6ae7d1ae2ca5593f6f65 201 Gene3D G3DSA:1.10.10.10 2 85 3.5E-24 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c17800 f1a010997cbe6ae7d1ae2ca5593f6f65 201 Pfam PF12802 MarR family 26 80 1.7E-6 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 VAPA_1c17800 f1a010997cbe6ae7d1ae2ca5593f6f65 201 SUPERFAMILY SSF46785 3 145 5.67E-24 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_2c08270 9d1d4d1fc8a27b38ac54f1c5d2787183 566 Gene3D G3DSA:3.40.50.620 280 566 1.8E-103 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold VAPA_2c08270 9d1d4d1fc8a27b38ac54f1c5d2787183 566 Gene3D G3DSA:3.60.110.10 1 266 7.1E-78 T 12-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily VAPA_2c08270 9d1d4d1fc8a27b38ac54f1c5d2787183 566 SUPERFAMILY SSF52402 276 549 1.01E-69 T 12-10-2018 VAPA_2c08270 9d1d4d1fc8a27b38ac54f1c5d2787183 566 Hamap MF_02090 Glutamine-dependent NAD(+) synthetase [nadE]. 2 566 27.531 T 12-10-2018 IPR014445 Glutamine-dependent NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.5.1|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 VAPA_2c08270 9d1d4d1fc8a27b38ac54f1c5d2787183 566 PIRSF PIRSF006630 264 566 3.0E-98 T 12-10-2018 IPR014445 Glutamine-dependent NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.5.1|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 VAPA_2c08270 9d1d4d1fc8a27b38ac54f1c5d2787183 566 PIRSF PIRSF006630 1 262 1.1E-68 T 12-10-2018 IPR014445 Glutamine-dependent NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.5.1|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 VAPA_2c08270 9d1d4d1fc8a27b38ac54f1c5d2787183 566 TIGRFAM TIGR00552 nadE: NAD+ synthetase 288 544 1.6E-57 T 12-10-2018 IPR003694 NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.1.5|Reactome: R-HSA-196807 VAPA_2c08270 9d1d4d1fc8a27b38ac54f1c5d2787183 566 Pfam PF00795 Carbon-nitrogen hydrolase 3 252 1.3E-18 T 12-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 VAPA_2c08270 9d1d4d1fc8a27b38ac54f1c5d2787183 566 Pfam PF02540 NAD synthase 282 541 1.6E-64 T 12-10-2018 IPR022310 NAD/GMP synthase VAPA_2c08270 9d1d4d1fc8a27b38ac54f1c5d2787183 566 SUPERFAMILY SSF56317 2 255 7.85E-49 T 12-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily VAPA_1c07590 f67342539801fe983c37bee2db54ed15 708 SMART SM00560 565 702 5.7E-4 T 12-10-2018 IPR006558 LamG-like jellyroll fold VAPA_1c07590 f67342539801fe983c37bee2db54ed15 708 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 550 705 1.1E-25 T 12-10-2018 VAPA_1c07590 f67342539801fe983c37bee2db54ed15 708 Gene3D G3DSA:1.50.10.100 126 404 1.4E-23 T 12-10-2018 IPR008929 Chondroitin AC/alginate lyase Reactome: R-HSA-2022923 VAPA_1c07590 f67342539801fe983c37bee2db54ed15 708 Pfam PF05426 Alginate lyase 150 356 2.6E-14 T 12-10-2018 IPR008397 Alginate lyase domain GO:0016829|GO:0042597 KEGG: 00051+4.2.2.3|MetaCyc: PWY-6986 VAPA_1c07590 f67342539801fe983c37bee2db54ed15 708 Gene3D G3DSA:2.60.40.10 444 536 2.7E-18 T 12-10-2018 IPR013783 Immunoglobulin-like fold VAPA_1c07590 f67342539801fe983c37bee2db54ed15 708 SUPERFAMILY SSF49265 439 530 3.53E-10 T 12-10-2018 IPR036116 Fibronectin type III superfamily GO:0005515 VAPA_1c07590 f67342539801fe983c37bee2db54ed15 708 SUPERFAMILY SSF48230 82 414 5.49E-53 T 12-10-2018 IPR008929 Chondroitin AC/alginate lyase Reactome: R-HSA-2022923 VAPA_1c07590 f67342539801fe983c37bee2db54ed15 708 Gene3D G3DSA:2.60.120.200 546 708 8.9E-23 T 12-10-2018 VAPA_1c07590 f67342539801fe983c37bee2db54ed15 708 SUPERFAMILY SSF49899 550 707 5.68E-24 T 12-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily VAPA_1c30520 0955eb1a8e4b24f72b17a3e1fd5726c4 279 Pfam PF00494 Squalene/phytoene synthase 13 263 8.9E-80 T 12-10-2018 VAPA_1c30520 0955eb1a8e4b24f72b17a3e1fd5726c4 279 TIGRFAM TIGR03465 HpnD: squalene synthase HpnD 10 275 7.2E-119 T 12-10-2018 IPR017828 Squalene synthase HpnD-like GO:0016117|GO:0016767 VAPA_1c30520 0955eb1a8e4b24f72b17a3e1fd5726c4 279 SUPERFAMILY SSF48576 5 276 1.44E-87 T 12-10-2018 IPR008949 Isoprenoid synthase domain superfamily VAPA_1c30520 0955eb1a8e4b24f72b17a3e1fd5726c4 279 ProSitePatterns PS01045 Squalene and phytoene synthases signature 2. 152 177 - T 12-10-2018 IPR019845 Squalene/phytoene synthase, conserved site GO:0016765 Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 VAPA_1c30520 0955eb1a8e4b24f72b17a3e1fd5726c4 279 Gene3D G3DSA:1.10.600.10 3 277 5.4E-84 T 12-10-2018 IPR008949 Isoprenoid synthase domain superfamily VAPA_2c01690 bc88b9224ecebfe3f830ac0bd267d311 148 SUPERFAMILY SSF55961 2 144 1.18E-42 T 12-10-2018 VAPA_2c01690 bc88b9224ecebfe3f830ac0bd267d311 148 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 13 143 3.7E-27 T 12-10-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like VAPA_2c01690 bc88b9224ecebfe3f830ac0bd267d311 148 Gene3D G3DSA:3.30.530.20 3 146 3.6E-39 T 12-10-2018 IPR023393 START-like domain superfamily VAPA_1c37290 966f5b18e57c11db44fb494663e2cb42 1080 Pfam PF00873 AcrB/AcrD/AcrF family 5 1059 3.3E-299 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 VAPA_1c37290 966f5b18e57c11db44fb494663e2cb42 1080 Gene3D G3DSA:3.30.70.1320 135 326 6.7E-203 T 12-10-2018 VAPA_1c37290 966f5b18e57c11db44fb494663e2cb42 1080 Gene3D G3DSA:1.20.1640.10 10 505 6.7E-203 T 12-10-2018 VAPA_1c37290 966f5b18e57c11db44fb494663e2cb42 1080 Gene3D G3DSA:3.30.2090.10 704 778 6.7E-203 T 12-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains VAPA_1c37290 966f5b18e57c11db44fb494663e2cb42 1080 Gene3D G3DSA:3.30.2090.10 822 840 1.3E-72 T 12-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains VAPA_1c37290 966f5b18e57c11db44fb494663e2cb42 1080 PRINTS PR00702 Acriflavin resistance protein family signature 330 353 9.9E-75 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 VAPA_1c37290 966f5b18e57c11db44fb494663e2cb42 1080 PRINTS PR00702 Acriflavin resistance protein family signature 10 34 9.9E-75 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 VAPA_1c37290 966f5b18e57c11db44fb494663e2cb42 1080 PRINTS PR00702 Acriflavin resistance protein family signature 463 486 9.9E-75 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 VAPA_1c37290 966f5b18e57c11db44fb494663e2cb42 1080 PRINTS PR00702 Acriflavin resistance protein family signature 38 56 9.9E-75 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 VAPA_1c37290 966f5b18e57c11db44fb494663e2cb42 1080 PRINTS PR00702 Acriflavin resistance protein family signature 385 409 9.9E-75 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 VAPA_1c37290 966f5b18e57c11db44fb494663e2cb42 1080 PRINTS PR00702 Acriflavin resistance protein family signature 545 562 9.9E-75 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 VAPA_1c37290 966f5b18e57c11db44fb494663e2cb42 1080 PRINTS PR00702 Acriflavin resistance protein family signature 357 378 9.9E-75 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 VAPA_1c37290 966f5b18e57c11db44fb494663e2cb42 1080 PRINTS PR00702 Acriflavin resistance protein family signature 438 461 9.9E-75 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 VAPA_1c37290 966f5b18e57c11db44fb494663e2cb42 1080 PRINTS PR00702 Acriflavin resistance protein family signature 608 622 9.9E-75 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 VAPA_1c37290 966f5b18e57c11db44fb494663e2cb42 1080 Gene3D G3DSA:3.30.70.1440 849 898 1.3E-72 T 12-10-2018 VAPA_1c37290 966f5b18e57c11db44fb494663e2cb42 1080 Gene3D G3DSA:3.30.70.1440 652 703 6.7E-203 T 12-10-2018 VAPA_1c37290 966f5b18e57c11db44fb494663e2cb42 1080 SUPERFAMILY SSF82714 183 266 1.06E-14 T 12-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains VAPA_1c37290 966f5b18e57c11db44fb494663e2cb42 1080 Gene3D G3DSA:3.30.70.1430 40 134 6.7E-203 T 12-10-2018 VAPA_1c37290 966f5b18e57c11db44fb494663e2cb42 1080 Gene3D G3DSA:3.30.70.1430 560 651 6.7E-203 T 12-10-2018 VAPA_1c37290 966f5b18e57c11db44fb494663e2cb42 1080 SUPERFAMILY SSF82693 40 131 1.92E-20 T 12-10-2018 VAPA_1c37290 966f5b18e57c11db44fb494663e2cb42 1080 SUPERFAMILY SSF82714 707 773 9.68E-10 T 12-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains VAPA_1c37290 966f5b18e57c11db44fb494663e2cb42 1080 SUPERFAMILY SSF82693 137 324 3.01E-22 T 12-10-2018 VAPA_1c37290 966f5b18e57c11db44fb494663e2cb42 1080 Gene3D G3DSA:3.30.2090.10 179 269 6.7E-203 T 12-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains VAPA_1c37290 966f5b18e57c11db44fb494663e2cb42 1080 SUPERFAMILY SSF82693 558 652 3.03E-12 T 12-10-2018 VAPA_1c37290 966f5b18e57c11db44fb494663e2cb42 1080 SUPERFAMILY SSF82866 841 1064 9.16E-43 T 12-10-2018 VAPA_1c37290 966f5b18e57c11db44fb494663e2cb42 1080 SUPERFAMILY SSF82866 290 491 2.49E-46 T 12-10-2018 VAPA_1c37290 966f5b18e57c11db44fb494663e2cb42 1080 Gene3D G3DSA:1.20.1640.10 506 559 6.7E-203 T 12-10-2018 VAPA_1c37290 966f5b18e57c11db44fb494663e2cb42 1080 Gene3D G3DSA:1.20.1640.10 899 1056 1.3E-72 T 12-10-2018 VAPA_1c45800 efd3d203f15af23e8003410f511aecb7 163 Gene3D G3DSA:1.10.10.10 8 162 6.1E-33 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c45800 efd3d203f15af23e8003410f511aecb7 163 SUPERFAMILY SSF46785 24 161 1.89E-31 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c45800 efd3d203f15af23e8003410f511aecb7 163 SMART SM00347 51 151 1.9E-16 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 VAPA_1c45800 efd3d203f15af23e8003410f511aecb7 163 Pfam PF12802 MarR family 57 115 7.1E-11 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 VAPA_1c45800 efd3d203f15af23e8003410f511aecb7 163 PRINTS PR00598 Bacterial regulatory protein MarR family signature 92 107 9.1E-9 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 VAPA_1c45800 efd3d203f15af23e8003410f511aecb7 163 PRINTS PR00598 Bacterial regulatory protein MarR family signature 111 127 9.1E-9 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 VAPA_1c45800 efd3d203f15af23e8003410f511aecb7 163 PRINTS PR00598 Bacterial regulatory protein MarR family signature 141 161 9.1E-9 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 VAPA_1c45800 efd3d203f15af23e8003410f511aecb7 163 PRINTS PR00598 Bacterial regulatory protein MarR family signature 75 91 9.1E-9 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 VAPA_1c18660 c1508b4424a247b8107090c24b625ff0 184 SUPERFAMILY SSF50249 128 184 2.57E-17 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold VAPA_1c18660 c1508b4424a247b8107090c24b625ff0 184 SMART SM00841 128 183 1.4E-28 T 12-10-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 VAPA_1c18660 c1508b4424a247b8107090c24b625ff0 184 Pfam PF09285 Elongation factor P, C-terminal 128 183 1.8E-24 T 12-10-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 VAPA_1c18660 c1508b4424a247b8107090c24b625ff0 184 Gene3D G3DSA:2.40.50.140 64 126 1.0E-21 T 12-10-2018 VAPA_1c18660 c1508b4424a247b8107090c24b625ff0 184 SMART SM01185 67 120 3.0E-20 T 12-10-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 VAPA_1c18660 c1508b4424a247b8107090c24b625ff0 184 TIGRFAM TIGR00038 efp: translation elongation factor P 4 184 1.3E-64 T 12-10-2018 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 VAPA_1c18660 c1508b4424a247b8107090c24b625ff0 184 ProSitePatterns PS01275 Elongation factor P signature. 149 168 - T 12-10-2018 IPR013852 Translation elongation factor P/YeiP, conserved site VAPA_1c18660 c1508b4424a247b8107090c24b625ff0 184 Pfam PF08207 Elongation factor P (EF-P) KOW-like domain 4 60 2.8E-18 T 12-10-2018 IPR013185 Translation elongation factor, KOW-like VAPA_1c18660 c1508b4424a247b8107090c24b625ff0 184 Gene3D G3DSA:2.30.30.30 1 63 3.5E-15 T 12-10-2018 IPR014722 Ribosomal protein L2, domain 2 VAPA_1c18660 c1508b4424a247b8107090c24b625ff0 184 Pfam PF01132 Elongation factor P (EF-P) OB domain 68 120 1.4E-17 T 12-10-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 VAPA_1c18660 c1508b4424a247b8107090c24b625ff0 184 PIRSF PIRSF005901 1 184 1.1E-57 T 12-10-2018 IPR020599 Translation elongation factor P/YeiP VAPA_1c18660 c1508b4424a247b8107090c24b625ff0 184 Hamap MF_00141 Elongation factor P [efp]. 1 184 46.672 T 12-10-2018 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 VAPA_1c18660 c1508b4424a247b8107090c24b625ff0 184 SUPERFAMILY SSF50104 1 62 6.62E-15 T 12-10-2018 IPR008991 Translation protein SH3-like domain superfamily VAPA_1c18660 c1508b4424a247b8107090c24b625ff0 184 Gene3D G3DSA:2.40.50.140 127 184 8.1E-27 T 12-10-2018 VAPA_1c18660 c1508b4424a247b8107090c24b625ff0 184 SUPERFAMILY SSF50249 65 126 4.8E-16 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold VAPA_1c05020 a823fe22a6a7ebc2f54cc43e3e8e9d05 876 SUPERFAMILY SSF52374 4 682 1.04E-139 T 12-10-2018 VAPA_1c05020 a823fe22a6a7ebc2f54cc43e3e8e9d05 876 Gene3D G3DSA:3.90.740.10 228 427 0.0 T 12-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 VAPA_1c05020 a823fe22a6a7ebc2f54cc43e3e8e9d05 876 Gene3D G3DSA:3.40.50.620 33 581 0.0 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold VAPA_1c05020 a823fe22a6a7ebc2f54cc43e3e8e9d05 876 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 42 53 - T 12-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 VAPA_1c05020 a823fe22a6a7ebc2f54cc43e3e8e9d05 876 TIGRFAM TIGR00396 leuS_bact: leucine--tRNA ligase 5 876 0.0 T 12-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 VAPA_1c05020 a823fe22a6a7ebc2f54cc43e3e8e9d05 876 Pfam PF08264 Anticodon-binding domain of tRNA 714 838 1.0E-13 T 12-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 VAPA_1c05020 a823fe22a6a7ebc2f54cc43e3e8e9d05 876 Gene3D G3DSA:1.10.730.10 8 808 0.0 T 12-10-2018 VAPA_1c05020 a823fe22a6a7ebc2f54cc43e3e8e9d05 876 Pfam PF13603 Leucyl-tRNA synthetase, Domain 2 222 415 3.3E-64 T 12-10-2018 IPR025709 Leucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 KEGG: 00970+6.1.1.4 VAPA_1c05020 a823fe22a6a7ebc2f54cc43e3e8e9d05 876 SUPERFAMILY SSF50677 231 425 2.51E-48 T 12-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 VAPA_1c05020 a823fe22a6a7ebc2f54cc43e3e8e9d05 876 PRINTS PR00985 Leucyl-tRNA synthetase signature 501 519 1.8E-49 T 12-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 VAPA_1c05020 a823fe22a6a7ebc2f54cc43e3e8e9d05 876 PRINTS PR00985 Leucyl-tRNA synthetase signature 185 198 1.8E-49 T 12-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 VAPA_1c05020 a823fe22a6a7ebc2f54cc43e3e8e9d05 876 PRINTS PR00985 Leucyl-tRNA synthetase signature 216 235 1.8E-49 T 12-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 VAPA_1c05020 a823fe22a6a7ebc2f54cc43e3e8e9d05 876 PRINTS PR00985 Leucyl-tRNA synthetase signature 572 582 1.8E-49 T 12-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 VAPA_1c05020 a823fe22a6a7ebc2f54cc43e3e8e9d05 876 PRINTS PR00985 Leucyl-tRNA synthetase signature 153 169 1.8E-49 T 12-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 VAPA_1c05020 a823fe22a6a7ebc2f54cc43e3e8e9d05 876 PRINTS PR00985 Leucyl-tRNA synthetase signature 127 144 1.8E-49 T 12-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 VAPA_1c05020 a823fe22a6a7ebc2f54cc43e3e8e9d05 876 PRINTS PR00985 Leucyl-tRNA synthetase signature 539 561 1.8E-49 T 12-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 VAPA_1c05020 a823fe22a6a7ebc2f54cc43e3e8e9d05 876 Hamap MF_00049_B Leucine--tRNA ligase [leuS]. 4 876 22.351 T 12-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 VAPA_1c05020 a823fe22a6a7ebc2f54cc43e3e8e9d05 876 Pfam PF09334 tRNA synthetases class I (M) 38 171 1.1E-18 T 12-10-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 VAPA_1c05020 a823fe22a6a7ebc2f54cc43e3e8e9d05 876 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 430 586 9.3E-8 T 12-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 VAPA_1c05020 a823fe22a6a7ebc2f54cc43e3e8e9d05 876 Gene3D G3DSA:3.10.20.590 818 876 3.2E-17 T 12-10-2018 VAPA_1c05020 a823fe22a6a7ebc2f54cc43e3e8e9d05 876 SUPERFAMILY SSF47323 678 876 1.85E-28 T 12-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 VAPA_1c05020 a823fe22a6a7ebc2f54cc43e3e8e9d05 876 Gene3D G3DSA:3.10.330.110 582 643 0.0 T 12-10-2018 VAPA_1c12210 7e50fa92cc764b673bc5d5d74b70837b 80 SUPERFAMILY SSF82657 1 79 3.92E-27 T 12-10-2018 IPR036065 BolA-like superfamily VAPA_1c12210 7e50fa92cc764b673bc5d5d74b70837b 80 Gene3D G3DSA:3.30.300.90 1 80 7.7E-28 T 12-10-2018 VAPA_1c12210 7e50fa92cc764b673bc5d5d74b70837b 80 Pfam PF01722 BolA-like protein 4 74 1.3E-17 T 12-10-2018 IPR002634 BolA protein VAPA_1c12210 7e50fa92cc764b673bc5d5d74b70837b 80 PIRSF PIRSF003113 1 80 4.0E-21 T 12-10-2018 IPR002634 BolA protein VAPA_1c16900 552cb55e14072aab8394733ec7054d77 263 SMART SM01092 169 261 2.2E-16 T 12-10-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal VAPA_1c16900 552cb55e14072aab8394733ec7054d77 263 SUPERFAMILY SSF55447 167 262 8.11E-19 T 12-10-2018 IPR036683 CO dehydrogenase flavoprotein, C-terminal domain superfamily VAPA_1c16900 552cb55e14072aab8394733ec7054d77 263 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 4 165 1.6E-43 T 12-10-2018 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 VAPA_1c16900 552cb55e14072aab8394733ec7054d77 263 Pfam PF03450 CO dehydrogenase flavoprotein C-terminal domain 194 260 1.7E-4 T 12-10-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal VAPA_1c16900 552cb55e14072aab8394733ec7054d77 263 Gene3D G3DSA:3.30.43.10 1 49 1.5E-13 T 12-10-2018 IPR016167 FAD-binding, type PCMH, subdomain 1 VAPA_1c16900 552cb55e14072aab8394733ec7054d77 263 Gene3D G3DSA:3.30.390.50 169 263 3.8E-12 T 12-10-2018 VAPA_1c16900 552cb55e14072aab8394733ec7054d77 263 SUPERFAMILY SSF56176 1 165 7.2E-48 T 12-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 VAPA_1c16900 552cb55e14072aab8394733ec7054d77 263 Gene3D G3DSA:3.30.465.10 53 166 9.8E-34 T 12-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 VAPA_1c55020 e36c6b3e7318cf50b6990f23e9d476ca 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 8.1E-8 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c55020 e36c6b3e7318cf50b6990f23e9d476ca 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 8.1E-8 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c55020 e36c6b3e7318cf50b6990f23e9d476ca 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 80 91 8.1E-8 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c55020 e36c6b3e7318cf50b6990f23e9d476ca 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 2.6E-25 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c55020 e36c6b3e7318cf50b6990f23e9d476ca 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 2.6E-25 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c55020 e36c6b3e7318cf50b6990f23e9d476ca 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 2.6E-25 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c55020 e36c6b3e7318cf50b6990f23e9d476ca 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 2.6E-25 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c55020 e36c6b3e7318cf50b6990f23e9d476ca 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 2.6E-25 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c55020 e36c6b3e7318cf50b6990f23e9d476ca 260 Gene3D G3DSA:3.40.50.720 3 257 1.7E-56 T 12-10-2018 VAPA_1c55020 e36c6b3e7318cf50b6990f23e9d476ca 260 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 141 169 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 VAPA_1c55020 e36c6b3e7318cf50b6990f23e9d476ca 260 SUPERFAMILY SSF51735 6 248 3.53E-58 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c55020 e36c6b3e7318cf50b6990f23e9d476ca 260 Pfam PF00106 short chain dehydrogenase 7 195 8.6E-42 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c16480 17a56ad542837bd5814710039ce6165b 342 ProSitePatterns PS00211 ABC transporters family signature. 166 180 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_1c16480 17a56ad542837bd5814710039ce6165b 342 Gene3D G3DSA:3.40.50.300 13 340 3.6E-100 T 12-10-2018 VAPA_1c16480 17a56ad542837bd5814710039ce6165b 342 SUPERFAMILY SSF52540 15 265 3.77E-68 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c16480 17a56ad542837bd5814710039ce6165b 342 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 245 309 2.0E-20 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 VAPA_1c16480 17a56ad542837bd5814710039ce6165b 342 Pfam PF00005 ABC transporter 36 193 7.7E-28 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c16480 17a56ad542837bd5814710039ce6165b 342 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 245 328 9.7E-26 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 VAPA_1c16480 17a56ad542837bd5814710039ce6165b 342 SMART SM00382 44 252 6.8E-15 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c39930 c9ac7a793e0ee28bdcb637071171e50a 541 Pfam PF00581 Rhodanese-like domain 17 105 7.6E-8 T 12-10-2018 IPR001763 Rhodanese-like domain VAPA_1c39930 c9ac7a793e0ee28bdcb637071171e50a 541 Pfam PF00581 Rhodanese-like domain 136 229 6.0E-9 T 12-10-2018 IPR001763 Rhodanese-like domain VAPA_1c39930 c9ac7a793e0ee28bdcb637071171e50a 541 Pfam PF00581 Rhodanese-like domain 384 481 1.2E-5 T 12-10-2018 IPR001763 Rhodanese-like domain VAPA_1c39930 c9ac7a793e0ee28bdcb637071171e50a 541 Gene3D G3DSA:3.40.250.10 380 494 3.1E-18 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily VAPA_1c39930 c9ac7a793e0ee28bdcb637071171e50a 541 SUPERFAMILY SSF52821 110 236 1.57E-27 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily VAPA_1c39930 c9ac7a793e0ee28bdcb637071171e50a 541 SUPERFAMILY SSF52821 259 353 3.54E-19 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily VAPA_1c39930 c9ac7a793e0ee28bdcb637071171e50a 541 Gene3D G3DSA:3.40.250.10 17 114 9.0E-18 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily VAPA_1c39930 c9ac7a793e0ee28bdcb637071171e50a 541 SMART SM00450 135 233 4.3E-7 T 12-10-2018 IPR001763 Rhodanese-like domain VAPA_1c39930 c9ac7a793e0ee28bdcb637071171e50a 541 SMART SM00450 10 109 1.2E-10 T 12-10-2018 IPR001763 Rhodanese-like domain VAPA_1c39930 c9ac7a793e0ee28bdcb637071171e50a 541 SMART SM00450 384 486 5.1E-5 T 12-10-2018 IPR001763 Rhodanese-like domain VAPA_1c39930 c9ac7a793e0ee28bdcb637071171e50a 541 SMART SM00450 271 359 0.068 T 12-10-2018 IPR001763 Rhodanese-like domain VAPA_1c39930 c9ac7a793e0ee28bdcb637071171e50a 541 Gene3D G3DSA:3.40.250.10 268 355 3.2E-17 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily VAPA_1c39930 c9ac7a793e0ee28bdcb637071171e50a 541 Gene3D G3DSA:3.40.250.10 131 238 4.6E-20 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily VAPA_1c39930 c9ac7a793e0ee28bdcb637071171e50a 541 SUPERFAMILY SSF52821 16 125 1.7E-22 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily VAPA_1c39930 c9ac7a793e0ee28bdcb637071171e50a 541 SUPERFAMILY SSF52821 380 540 5.37E-27 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily VAPA_2c07740 5e710af760e3374ef900787fbc331475 406 SUPERFAMILY SSF46785 333 377 2.18E-5 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_2c06110 f7d4b7cd20d1cfaa82e882de0a71ef0f 1013 Gene3D G3DSA:1.10.1200.10 497 584 2.7E-19 T 12-10-2018 IPR036736 ACP-like superfamily VAPA_2c06110 f7d4b7cd20d1cfaa82e882de0a71ef0f 1013 Gene3D G3DSA:3.30.300.30 399 496 5.1E-28 T 12-10-2018 VAPA_2c06110 f7d4b7cd20d1cfaa82e882de0a71ef0f 1013 Pfam PF13193 AMP-binding enzyme C-terminal domain 416 488 1.4E-10 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain VAPA_2c06110 f7d4b7cd20d1cfaa82e882de0a71ef0f 1013 SUPERFAMILY SSF47336 507 608 1.03E-16 T 12-10-2018 IPR036736 ACP-like superfamily VAPA_2c06110 f7d4b7cd20d1cfaa82e882de0a71ef0f 1013 Pfam PF00501 AMP-binding enzyme 36 404 1.1E-63 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 VAPA_2c06110 f7d4b7cd20d1cfaa82e882de0a71ef0f 1013 Gene3D G3DSA:3.30.559.10 600 962 4.9E-63 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 VAPA_2c06110 f7d4b7cd20d1cfaa82e882de0a71ef0f 1013 ProSitePatterns PS00012 Phosphopantetheine attachment site. 537 552 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site VAPA_2c06110 f7d4b7cd20d1cfaa82e882de0a71ef0f 1013 ProSitePatterns PS00455 Putative AMP-binding domain signature. 151 162 - T 12-10-2018 IPR020845 AMP-binding, conserved site VAPA_2c06110 f7d4b7cd20d1cfaa82e882de0a71ef0f 1013 SUPERFAMILY SSF52777 780 1012 1.45E-30 T 12-10-2018 VAPA_2c06110 f7d4b7cd20d1cfaa82e882de0a71ef0f 1013 Pfam PF00668 Condensation domain 599 1010 2.5E-45 T 12-10-2018 IPR001242 Condensation domain VAPA_2c06110 f7d4b7cd20d1cfaa82e882de0a71ef0f 1013 SMART SM00823 Phosphopantetheine attachment site 513 582 1.1E-6 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 VAPA_2c06110 f7d4b7cd20d1cfaa82e882de0a71ef0f 1013 Pfam PF00550 Phosphopantetheine attachment site 516 578 5.8E-13 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain VAPA_2c06110 f7d4b7cd20d1cfaa82e882de0a71ef0f 1013 SUPERFAMILY SSF56801 20 507 2.22E-105 T 12-10-2018 VAPA_2c06110 f7d4b7cd20d1cfaa82e882de0a71ef0f 1013 SUPERFAMILY SSF52777 600 773 3.67E-26 T 12-10-2018 VAPA_2c06110 f7d4b7cd20d1cfaa82e882de0a71ef0f 1013 Gene3D G3DSA:3.30.559.30 778 1011 4.9E-63 T 12-10-2018 VAPA_2c06110 f7d4b7cd20d1cfaa82e882de0a71ef0f 1013 Gene3D G3DSA:3.40.50.12780 20 397 3.5E-77 T 12-10-2018 VAPA_2c04950 1f0546298f8cb7f388db832cdf977720 423 SUPERFAMILY SSF51905 3 338 3.09E-25 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_2c04950 1f0546298f8cb7f388db832cdf977720 423 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 302 1.9E-18 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 VAPA_2c04950 1f0546298f8cb7f388db832cdf977720 423 Gene3D G3DSA:3.50.50.100 1 415 1.3E-159 T 12-10-2018 VAPA_2c04950 1f0546298f8cb7f388db832cdf977720 423 SUPERFAMILY SSF51905 157 240 9.15E-7 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_2c05790 515149c08ca8b5b05f749558a81bbc7d 687 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 403 675 1.8E-63 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_2c05790 515149c08ca8b5b05f749558a81bbc7d 687 Gene3D G3DSA:3.40.190.150 384 669 2.1E-96 T 12-10-2018 VAPA_2c05790 515149c08ca8b5b05f749558a81bbc7d 687 Pfam PF04303 PrpF protein 17 365 8.4E-112 T 12-10-2018 IPR007400 PrpF protein VAPA_2c05790 515149c08ca8b5b05f749558a81bbc7d 687 Gene3D G3DSA:3.40.190.10 481 604 2.1E-96 T 12-10-2018 VAPA_2c05790 515149c08ca8b5b05f749558a81bbc7d 687 SUPERFAMILY SSF54506 14 179 3.92E-60 T 12-10-2018 VAPA_2c05790 515149c08ca8b5b05f749558a81bbc7d 687 Gene3D G3DSA:3.10.310.10 180 350 5.3E-114 T 12-10-2018 VAPA_2c05790 515149c08ca8b5b05f749558a81bbc7d 687 SUPERFAMILY SSF54506 184 367 1.18E-54 T 12-10-2018 VAPA_2c05790 515149c08ca8b5b05f749558a81bbc7d 687 SUPERFAMILY SSF53850 469 641 4.34E-8 T 12-10-2018 VAPA_2c05790 515149c08ca8b5b05f749558a81bbc7d 687 Gene3D G3DSA:3.10.310.10 18 362 5.3E-114 T 12-10-2018 VAPA_1c39470 0794b52c3786b1d560013cea28cf053c 271 Pfam PF01614 Bacterial transcriptional regulator 146 266 5.1E-30 T 12-10-2018 IPR014757 Transcription regulator IclR, C-terminal VAPA_1c39470 0794b52c3786b1d560013cea28cf053c 271 SUPERFAMILY SSF46785 29 99 1.54E-13 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c39470 0794b52c3786b1d560013cea28cf053c 271 Gene3D G3DSA:1.10.10.10 22 94 5.5E-17 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c39470 0794b52c3786b1d560013cea28cf053c 271 Pfam PF09339 IclR helix-turn-helix domain 29 79 4.0E-15 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 VAPA_1c39470 0794b52c3786b1d560013cea28cf053c 271 Gene3D G3DSA:3.30.450.40 103 271 4.0E-54 T 12-10-2018 IPR029016 GAF-like domain superfamily VAPA_1c39470 0794b52c3786b1d560013cea28cf053c 271 SUPERFAMILY SSF55781 101 271 3.73E-50 T 12-10-2018 VAPA_1c39470 0794b52c3786b1d560013cea28cf053c 271 SMART SM00346 27 117 2.8E-10 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 VAPA_1c16320 1e09e89e831a2361c4db72451365243d 151 ProSitePatterns PS00196 Type-1 copper (blue) proteins signature. 127 143 - T 12-10-2018 IPR028871 Blue (type 1) copper protein, binding site VAPA_1c16320 1e09e89e831a2361c4db72451365243d 151 ProDom PD003655 COPPER ELECTRON AZURIN METAL-BINDING PERIPLASMIC PRECURSOR SIGNAL SEQUENCING DIRECT MEMBRANE 29 147 2.0E-49 T 12-10-2018 VAPA_1c16320 1e09e89e831a2361c4db72451365243d 151 SUPERFAMILY SSF49503 23 149 2.76E-43 T 12-10-2018 IPR008972 Cupredoxin VAPA_1c16320 1e09e89e831a2361c4db72451365243d 151 TIGRFAM TIGR02695 azurin: azurin 25 149 9.0E-60 T 12-10-2018 IPR014068 Azurin VAPA_1c16320 1e09e89e831a2361c4db72451365243d 151 Pfam PF00127 Copper binding proteins, plastocyanin/azurin family 23 149 6.0E-28 T 12-10-2018 IPR000923 Blue (type 1) copper domain GO:0005507|GO:0009055 VAPA_1c16320 1e09e89e831a2361c4db72451365243d 151 Gene3D G3DSA:2.60.40.420 23 150 5.4E-44 T 12-10-2018 IPR008972 Cupredoxin VAPA_1c03580 6509bf5b28b77308ab4e926090155b94 147 Pfam PF13565 Homeodomain-like domain 60 137 3.3E-11 T 12-10-2018 VAPA_1c03580 6509bf5b28b77308ab4e926090155b94 147 SUPERFAMILY SSF46689 28 139 3.76E-7 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 VAPA_1c45270 6509bf5b28b77308ab4e926090155b94 147 Pfam PF13565 Homeodomain-like domain 60 137 3.3E-11 T 12-10-2018 VAPA_1c45270 6509bf5b28b77308ab4e926090155b94 147 SUPERFAMILY SSF46689 28 139 3.76E-7 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 VAPA_1c10550 6509bf5b28b77308ab4e926090155b94 147 Pfam PF13565 Homeodomain-like domain 60 137 3.3E-11 T 12-10-2018 VAPA_1c10550 6509bf5b28b77308ab4e926090155b94 147 SUPERFAMILY SSF46689 28 139 3.76E-7 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 VAPA_1c40450 6509bf5b28b77308ab4e926090155b94 147 Pfam PF13565 Homeodomain-like domain 60 137 3.3E-11 T 12-10-2018 VAPA_1c40450 6509bf5b28b77308ab4e926090155b94 147 SUPERFAMILY SSF46689 28 139 3.76E-7 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 VAPA_2c12040 7b1b8b739657f6741fb02f9c372f646c 477 Gene3D G3DSA:3.30.465.10 101 222 3.1E-45 T 12-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 VAPA_2c12040 7b1b8b739657f6741fb02f9c372f646c 477 SUPERFAMILY SSF56176 14 223 1.6E-73 T 12-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 VAPA_2c12040 7b1b8b739657f6741fb02f9c372f646c 477 Gene3D G3DSA:3.30.70.2190 223 344 8.5E-30 T 12-10-2018 VAPA_2c12040 7b1b8b739657f6741fb02f9c372f646c 477 Gene3D G3DSA:3.30.43.10 3 99 2.6E-25 T 12-10-2018 IPR016167 FAD-binding, type PCMH, subdomain 1 VAPA_2c12040 7b1b8b739657f6741fb02f9c372f646c 477 SUPERFAMILY SSF55103 197 474 4.09E-49 T 12-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 VAPA_2c12040 7b1b8b739657f6741fb02f9c372f646c 477 Pfam PF01565 FAD binding domain 46 183 2.7E-36 T 12-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 VAPA_2c12040 7b1b8b739657f6741fb02f9c372f646c 477 Gene3D G3DSA:3.30.70.2740 348 433 1.2E-24 T 12-10-2018 VAPA_2c12040 7b1b8b739657f6741fb02f9c372f646c 477 Gene3D G3DSA:1.10.45.10 434 474 6.2E-12 T 12-10-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 VAPA_2c12040 7b1b8b739657f6741fb02f9c372f646c 477 Pfam PF02913 FAD linked oxidases, C-terminal domain 223 473 2.3E-51 T 12-10-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 VAPA_1c41470 48f3c16da1f99e4fa80ee96be1c649ab 312 SUPERFAMILY SSF52821 182 309 3.54E-23 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily VAPA_1c41470 48f3c16da1f99e4fa80ee96be1c649ab 312 SMART SM00450 207 308 4.5E-7 T 12-10-2018 IPR001763 Rhodanese-like domain VAPA_1c41470 48f3c16da1f99e4fa80ee96be1c649ab 312 Pfam PF00581 Rhodanese-like domain 208 304 3.6E-5 T 12-10-2018 IPR001763 Rhodanese-like domain VAPA_1c41470 48f3c16da1f99e4fa80ee96be1c649ab 312 Pfam PF09335 SNARE associated Golgi protein 29 155 5.7E-11 T 12-10-2018 IPR032816 SNARE associated Golgi protein VAPA_1c41470 48f3c16da1f99e4fa80ee96be1c649ab 312 Gene3D G3DSA:3.40.250.10 203 310 1.8E-16 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily VAPA_1c25380 8c482f42c6f5a7295d39dbebdb2b2da8 285 TIGRFAM TIGR00097 HMP-P_kinase: hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 18 273 1.1E-94 T 12-10-2018 IPR004399 Hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase GO:0008972|GO:0009228 KEGG: 00730+2.7.1.49|MetaCyc: PWY-6910|MetaCyc: PWY-7356|MetaCyc: PWY-7357 VAPA_1c25380 8c482f42c6f5a7295d39dbebdb2b2da8 285 SUPERFAMILY SSF53613 15 275 5.14E-77 T 12-10-2018 IPR029056 Ribokinase-like VAPA_1c25380 8c482f42c6f5a7295d39dbebdb2b2da8 285 Gene3D G3DSA:3.40.1190.20 3 280 1.4E-104 T 12-10-2018 IPR029056 Ribokinase-like VAPA_1c25380 8c482f42c6f5a7295d39dbebdb2b2da8 285 Pfam PF08543 Phosphomethylpyrimidine kinase 25 272 3.1E-94 T 12-10-2018 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-6798695|Reactome: R-HSA-964975 VAPA_1c29910 43d9d924f14ac95ed423f1e531063ce8 416 Gene3D G3DSA:2.40.30.170 68 320 5.4E-97 T 12-10-2018 VAPA_1c29910 43d9d924f14ac95ed423f1e531063ce8 416 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 55 391 1.9E-85 T 12-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 VAPA_1c29910 43d9d924f14ac95ed423f1e531063ce8 416 SUPERFAMILY SSF111369 69 315 8.37E-65 T 12-10-2018 VAPA_1c29910 43d9d924f14ac95ed423f1e531063ce8 416 Gene3D G3DSA:2.40.420.20 321 389 5.4E-97 T 12-10-2018 VAPA_1c29910 43d9d924f14ac95ed423f1e531063ce8 416 Gene3D G3DSA:2.40.50.100 79 224 5.4E-97 T 12-10-2018 VAPA_1c29910 43d9d924f14ac95ed423f1e531063ce8 416 Gene3D G3DSA:1.10.287.470 114 187 5.4E-97 T 12-10-2018 VAPA_1c29910 43d9d924f14ac95ed423f1e531063ce8 416 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 81 310 2.1E-16 T 12-10-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain VAPA_1c38690 ddccdbb3121605f0b41bed705c61bff2 1113 SUPERFAMILY SSF56801 482 1035 3.53E-159 T 12-10-2018 VAPA_1c38690 ddccdbb3121605f0b41bed705c61bff2 1113 Gene3D G3DSA:1.10.1200.10 1008 1096 5.4E-29 T 12-10-2018 IPR036736 ACP-like superfamily VAPA_1c38690 ddccdbb3121605f0b41bed705c61bff2 1113 PIRSF PIRSF001617 239 967 2.1E-46 T 12-10-2018 VAPA_1c38690 ddccdbb3121605f0b41bed705c61bff2 1113 PIRSF PIRSF001617 961 1102 5.9E-21 T 12-10-2018 VAPA_1c38690 ddccdbb3121605f0b41bed705c61bff2 1113 Gene3D G3DSA:3.30.559.30 235 481 4.7E-135 T 12-10-2018 VAPA_1c38690 ddccdbb3121605f0b41bed705c61bff2 1113 SMART SM00823 Phosphopantetheine attachment site 1022 1091 7.1E-6 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 VAPA_1c38690 ddccdbb3121605f0b41bed705c61bff2 1113 SUPERFAMILY SSF52777 51 231 3.34E-45 T 12-10-2018 VAPA_1c38690 ddccdbb3121605f0b41bed705c61bff2 1113 SMART SM01294 1023 1087 0.0065 T 12-10-2018 VAPA_1c38690 ddccdbb3121605f0b41bed705c61bff2 1113 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 538 939 2.2E-139 T 12-10-2018 IPR010071 Amino acid adenylation domain VAPA_1c38690 ddccdbb3121605f0b41bed705c61bff2 1113 SUPERFAMILY SSF52777 238 481 7.67E-59 T 12-10-2018 VAPA_1c38690 ddccdbb3121605f0b41bed705c61bff2 1113 Gene3D G3DSA:3.40.50.12780 504 909 3.9E-148 T 12-10-2018 VAPA_1c38690 ddccdbb3121605f0b41bed705c61bff2 1113 Pfam PF00668 Condensation domain 48 497 1.1E-94 T 12-10-2018 IPR001242 Condensation domain VAPA_1c38690 ddccdbb3121605f0b41bed705c61bff2 1113 Gene3D G3DSA:3.30.300.30 910 1007 2.9E-34 T 12-10-2018 VAPA_1c38690 ddccdbb3121605f0b41bed705c61bff2 1113 ProSitePatterns PS00455 Putative AMP-binding domain signature. 658 669 - T 12-10-2018 IPR020845 AMP-binding, conserved site VAPA_1c38690 ddccdbb3121605f0b41bed705c61bff2 1113 Gene3D G3DSA:3.30.559.10 49 426 4.7E-135 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 VAPA_1c38690 ddccdbb3121605f0b41bed705c61bff2 1113 Pfam PF00550 Phosphopantetheine attachment site 1024 1087 1.4E-14 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain VAPA_1c38690 ddccdbb3121605f0b41bed705c61bff2 1113 Pfam PF00501 AMP-binding enzyme 518 915 2.7E-98 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 VAPA_1c38690 ddccdbb3121605f0b41bed705c61bff2 1113 SUPERFAMILY SSF47336 1015 1087 1.14E-21 T 12-10-2018 IPR036736 ACP-like superfamily VAPA_1c38690 ddccdbb3121605f0b41bed705c61bff2 1113 Pfam PF13193 AMP-binding enzyme C-terminal domain 923 997 1.7E-11 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain VAPA_1c38690 ddccdbb3121605f0b41bed705c61bff2 1113 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1046 1061 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site VAPA_1c00270 a429d141d9f04d412d611b835e4dd697 260 Gene3D G3DSA:3.40.50.2300 2 134 9.8E-33 T 12-10-2018 VAPA_1c00270 a429d141d9f04d412d611b835e4dd697 260 Gene3D G3DSA:1.10.10.10 162 257 2.2E-27 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c00270 a429d141d9f04d412d611b835e4dd697 260 Pfam PF00072 Response regulator receiver domain 7 122 8.3E-23 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_1c00270 a429d141d9f04d412d611b835e4dd697 260 Pfam PF00486 Transcriptional regulatory protein, C terminal 178 252 8.2E-23 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 VAPA_1c00270 a429d141d9f04d412d611b835e4dd697 260 SMART SM00862 176 252 4.0E-23 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 VAPA_1c00270 a429d141d9f04d412d611b835e4dd697 260 SUPERFAMILY SSF46894 163 253 5.39E-24 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 VAPA_1c00270 a429d141d9f04d412d611b835e4dd697 260 SMART SM00448 5 121 1.3E-39 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_1c00270 a429d141d9f04d412d611b835e4dd697 260 SUPERFAMILY SSF52172 4 131 1.85E-36 T 12-10-2018 IPR011006 CheY-like superfamily VAPA_2c07550 ccd50372959c83f133fa692aba1cbded 457 Gene3D G3DSA:1.10.3080.10 22 435 6.3E-86 T 12-10-2018 IPR014743 Chloride channel, core Reactome: R-HSA-2672351 VAPA_2c07550 ccd50372959c83f133fa692aba1cbded 457 PRINTS PR00762 Chloride channel signature 337 357 2.5E-24 T 12-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 VAPA_2c07550 ccd50372959c83f133fa692aba1cbded 457 PRINTS PR00762 Chloride channel signature 170 189 2.5E-24 T 12-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 VAPA_2c07550 ccd50372959c83f133fa692aba1cbded 457 PRINTS PR00762 Chloride channel signature 366 382 2.5E-24 T 12-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 VAPA_2c07550 ccd50372959c83f133fa692aba1cbded 457 PRINTS PR00762 Chloride channel signature 83 100 2.5E-24 T 12-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 VAPA_2c07550 ccd50372959c83f133fa692aba1cbded 457 PRINTS PR00762 Chloride channel signature 384 403 2.5E-24 T 12-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 VAPA_2c07550 ccd50372959c83f133fa692aba1cbded 457 Pfam PF00654 Voltage gated chloride channel 72 416 1.9E-78 T 12-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 VAPA_2c07550 ccd50372959c83f133fa692aba1cbded 457 SUPERFAMILY SSF81340 10 431 1.83E-87 T 12-10-2018 IPR014743 Chloride channel, core Reactome: R-HSA-2672351 VAPA_2c08180 818afafb8e584e7c3bf2325bbdd636a8 201 Pfam PF13338 Transcriptional regulator, AbiEi antitoxin 8 55 7.2E-7 T 12-10-2018 IPR025159 Transcriptional regulator, AbiEi antitoxin VAPA_1c23410 a74c4f81484d1b2c4b65bd6de6aab87e 553 Pfam PF02817 e3 binding domain 245 280 4.2E-16 T 12-10-2018 IPR004167 Peripheral subunit-binding domain GO:0016746 Reactome: R-HSA-389661 VAPA_1c23410 a74c4f81484d1b2c4b65bd6de6aab87e 553 TIGRFAM TIGR01348 PDHac_trf_long: dihydrolipoyllysine-residue acetyltransferase 95 553 1.3E-198 T 12-10-2018 IPR006256 Dihydrolipoamide acetyltransferase pyruvate dehydrogenase complex GO:0004742|GO:0006096|GO:0045254 KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00620+2.3.1.12 VAPA_1c23410 a74c4f81484d1b2c4b65bd6de6aab87e 553 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 326 552 1.2E-78 T 12-10-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0016746 Reactome: R-HSA-389661 VAPA_1c23410 a74c4f81484d1b2c4b65bd6de6aab87e 553 Gene3D G3DSA:4.10.320.10 246 288 4.6E-18 T 12-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 VAPA_1c23410 a74c4f81484d1b2c4b65bd6de6aab87e 553 Gene3D G3DSA:3.30.559.10 310 553 3.0E-93 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 VAPA_1c23410 a74c4f81484d1b2c4b65bd6de6aab87e 553 Pfam PF00364 Biotin-requiring enzyme 5 76 9.8E-21 T 12-10-2018 IPR000089 Biotin/lipoyl attachment VAPA_1c23410 a74c4f81484d1b2c4b65bd6de6aab87e 553 Pfam PF00364 Biotin-requiring enzyme 120 191 8.0E-23 T 12-10-2018 IPR000089 Biotin/lipoyl attachment VAPA_1c23410 a74c4f81484d1b2c4b65bd6de6aab87e 553 SUPERFAMILY SSF52777 315 553 2.4E-84 T 12-10-2018 VAPA_1c23410 a74c4f81484d1b2c4b65bd6de6aab87e 553 SUPERFAMILY SSF47005 239 283 2.22E-12 T 12-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 VAPA_1c23410 a74c4f81484d1b2c4b65bd6de6aab87e 553 Gene3D G3DSA:2.40.50.100 118 194 1.5E-21 T 12-10-2018 VAPA_1c23410 a74c4f81484d1b2c4b65bd6de6aab87e 553 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 142 171 - T 12-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 VAPA_1c23410 a74c4f81484d1b2c4b65bd6de6aab87e 553 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 27 56 - T 12-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 VAPA_1c23410 a74c4f81484d1b2c4b65bd6de6aab87e 553 SUPERFAMILY SSF51230 118 211 1.31E-24 T 12-10-2018 IPR011053 Single hybrid motif VAPA_1c23410 a74c4f81484d1b2c4b65bd6de6aab87e 553 Gene3D G3DSA:2.40.50.100 2 81 3.2E-20 T 12-10-2018 VAPA_1c23410 a74c4f81484d1b2c4b65bd6de6aab87e 553 SUPERFAMILY SSF51230 2 96 5.5E-24 T 12-10-2018 IPR011053 Single hybrid motif VAPA_1c10820 cceecc8e0df2f2b2910df711b0689a1c 309 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 9 66 2.2E-17 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c10820 cceecc8e0df2f2b2910df711b0689a1c 309 SUPERFAMILY SSF46785 8 115 3.17E-22 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c10820 cceecc8e0df2f2b2910df711b0689a1c 309 Gene3D G3DSA:3.40.190.10 166 271 1.8E-63 T 12-10-2018 VAPA_1c10820 cceecc8e0df2f2b2910df711b0689a1c 309 Gene3D G3DSA:3.40.190.10 94 296 1.8E-63 T 12-10-2018 VAPA_1c10820 cceecc8e0df2f2b2910df711b0689a1c 309 Gene3D G3DSA:1.10.10.10 7 87 2.9E-22 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c10820 cceecc8e0df2f2b2910df711b0689a1c 309 Pfam PF03466 LysR substrate binding domain 91 297 3.2E-40 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_1c10820 cceecc8e0df2f2b2910df711b0689a1c 309 SUPERFAMILY SSF53850 93 302 1.55E-41 T 12-10-2018 VAPA_1c20240 5125c2080ea2e8d59169d0576ec7ba8c 323 PIRSF PIRSF017082 1 322 8.3E-69 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c20240 5125c2080ea2e8d59169d0576ec7ba8c 323 SUPERFAMILY SSF53850 114 278 9.05E-7 T 12-10-2018 VAPA_1c20240 5125c2080ea2e8d59169d0576ec7ba8c 323 Gene3D G3DSA:3.40.190.150 28 312 4.1E-93 T 12-10-2018 VAPA_1c20240 5125c2080ea2e8d59169d0576ec7ba8c 323 Gene3D G3DSA:3.40.190.10 124 247 4.1E-93 T 12-10-2018 VAPA_1c20240 5125c2080ea2e8d59169d0576ec7ba8c 323 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 46 319 2.2E-63 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c26620 076616864dba6f9bb820e67714a53f2c 547 Pfam PF02470 MlaD protein 171 246 1.1E-9 T 12-10-2018 IPR003399 Mce/MlaD VAPA_1c26620 076616864dba6f9bb820e67714a53f2c 547 Pfam PF02470 MlaD protein 56 146 1.3E-12 T 12-10-2018 IPR003399 Mce/MlaD VAPA_1c26620 076616864dba6f9bb820e67714a53f2c 547 Pfam PF02470 MlaD protein 298 402 9.9E-17 T 12-10-2018 IPR003399 Mce/MlaD VAPA_1c08190 d31a7833a111ff1b17b6380241b6876c 633 Gene3D G3DSA:3.40.50.2000 449 579 4.9E-12 T 12-10-2018 VAPA_1c08190 d31a7833a111ff1b17b6380241b6876c 633 Pfam PF00534 Glycosyl transferases group 1 497 552 3.5E-7 T 12-10-2018 IPR001296 Glycosyl transferase, family 1 VAPA_1c08190 d31a7833a111ff1b17b6380241b6876c 633 SUPERFAMILY SSF53756 321 613 9.94E-21 T 12-10-2018 VAPA_1c08040 2ec9f1e2cd6078656d53b09f2f644368 213 Gene3D G3DSA:1.20.1050.10 88 207 8.7E-39 T 12-10-2018 VAPA_1c08040 2ec9f1e2cd6078656d53b09f2f644368 213 Pfam PF13417 Glutathione S-transferase, N-terminal domain 9 82 1.8E-10 T 12-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 VAPA_1c08040 2ec9f1e2cd6078656d53b09f2f644368 213 SUPERFAMILY SSF52833 1 88 1.07E-19 T 12-10-2018 IPR036249 Thioredoxin-like superfamily VAPA_1c08040 2ec9f1e2cd6078656d53b09f2f644368 213 Gene3D G3DSA:3.40.30.10 1 87 2.0E-30 T 12-10-2018 VAPA_1c08040 2ec9f1e2cd6078656d53b09f2f644368 213 Pfam PF00043 Glutathione S-transferase, C-terminal domain 124 202 1.7E-7 T 12-10-2018 IPR004046 Glutathione S-transferase, C-terminal VAPA_1c08040 2ec9f1e2cd6078656d53b09f2f644368 213 SUPERFAMILY SSF47616 76 210 3.76E-27 T 12-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily VAPA_2c07890 e5915814fa04c09fed7ea646533087af 507 Gene3D G3DSA:2.40.30.170 231 327 2.6E-21 T 12-10-2018 VAPA_2c07890 e5915814fa04c09fed7ea646533087af 507 SUPERFAMILY SSF111369 129 325 9.81E-13 T 12-10-2018 VAPA_2c07890 e5915814fa04c09fed7ea646533087af 507 Gene3D G3DSA:2.40.30.170 115 128 7.8E-7 T 12-10-2018 VAPA_2c07890 e5915814fa04c09fed7ea646533087af 507 Gene3D G3DSA:2.40.50.100 129 163 7.8E-7 T 12-10-2018 VAPA_2c07890 e5915814fa04c09fed7ea646533087af 507 Gene3D G3DSA:2.40.420.20 104 114 7.8E-7 T 12-10-2018 VAPA_2c07890 e5915814fa04c09fed7ea646533087af 507 Gene3D G3DSA:1.10.287.470 164 196 7.8E-7 T 12-10-2018 VAPA_2c07890 e5915814fa04c09fed7ea646533087af 507 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 212 397 2.1E-40 T 12-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 VAPA_2c07890 e5915814fa04c09fed7ea646533087af 507 Gene3D G3DSA:2.40.420.20 328 413 1.4E-24 T 12-10-2018 VAPA_2c07890 e5915814fa04c09fed7ea646533087af 507 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 113 320 6.6E-62 T 12-10-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain VAPA_2c07890 e5915814fa04c09fed7ea646533087af 507 Pfam PF11604 Copper binding periplasmic protein CusF 435 499 1.0E-19 T 12-10-2018 IPR021647 Copper binding periplasmic protein CusF VAPA_2c07890 e5915814fa04c09fed7ea646533087af 507 Gene3D G3DSA:2.40.50.320 428 507 3.8E-24 T 12-10-2018 VAPA_1c46570 ff5a336716d5ea5352e3cf27a603750e 337 SUPERFAMILY SSF48179 198 319 3.26E-30 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 VAPA_1c46570 ff5a336716d5ea5352e3cf27a603750e 337 Pfam PF08546 Ketopantoate reductase PanE/ApbA C terminal 198 319 2.8E-28 T 12-10-2018 IPR013752 Ketopantoate reductase, C-terminal domain VAPA_1c46570 ff5a336716d5ea5352e3cf27a603750e 337 Gene3D G3DSA:3.40.50.720 1 196 2.2E-64 T 12-10-2018 VAPA_1c46570 ff5a336716d5ea5352e3cf27a603750e 337 Pfam PF02558 Ketopantoate reductase PanE/ApbA 3 172 1.7E-26 T 12-10-2018 IPR013332 Ketopantoate reductase, N-terminal domain VAPA_1c46570 ff5a336716d5ea5352e3cf27a603750e 337 Gene3D G3DSA:1.10.1040.10 198 334 1.0E-41 T 12-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 VAPA_1c46570 ff5a336716d5ea5352e3cf27a603750e 337 SUPERFAMILY SSF51735 1 204 8.59E-18 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c18300 d4250ef2c070c2fdd39701905314cbe1 459 Gene3D G3DSA:3.30.870.10 98 287 6.2E-35 T 12-10-2018 VAPA_1c18300 d4250ef2c070c2fdd39701905314cbe1 459 SMART SM00155 199 226 7.3 T 12-10-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 VAPA_1c18300 d4250ef2c070c2fdd39701905314cbe1 459 SMART SM00155 375 402 0.21 T 12-10-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 VAPA_1c18300 d4250ef2c070c2fdd39701905314cbe1 459 SUPERFAMILY SSF56024 78 293 2.1E-43 T 12-10-2018 VAPA_1c18300 d4250ef2c070c2fdd39701905314cbe1 459 SUPERFAMILY SSF56024 280 428 3.14E-31 T 12-10-2018 VAPA_1c18300 d4250ef2c070c2fdd39701905314cbe1 459 Pfam PF13091 PLD-like domain 309 427 2.8E-20 T 12-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 VAPA_1c18300 d4250ef2c070c2fdd39701905314cbe1 459 Pfam PF13091 PLD-like domain 118 260 1.8E-12 T 12-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 VAPA_1c18300 d4250ef2c070c2fdd39701905314cbe1 459 Pfam PF13396 Phospholipase_D-nuclease N-terminal 19 65 5.4E-5 T 12-10-2018 IPR027379 Cardiolipin synthase N-terminal VAPA_1c18300 d4250ef2c070c2fdd39701905314cbe1 459 Gene3D G3DSA:3.30.870.10 293 434 5.8E-22 T 12-10-2018 VAPA_1c10290 e4592be04f18aa41861b78ccc7072962 124 TIGRFAM TIGR00526 folB_dom: FolB domain 9 120 4.9E-13 T 12-10-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 VAPA_1c10290 e4592be04f18aa41861b78ccc7072962 124 Gene3D G3DSA:3.30.1130.10 2 122 1.5E-30 T 12-10-2018 VAPA_1c10290 e4592be04f18aa41861b78ccc7072962 124 Pfam PF02152 Dihydroneopterin aldolase 12 115 9.7E-21 T 12-10-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 VAPA_1c10290 e4592be04f18aa41861b78ccc7072962 124 SMART SM00905 11 121 6.4E-27 T 12-10-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 VAPA_1c10290 e4592be04f18aa41861b78ccc7072962 124 SUPERFAMILY SSF55620 10 118 1.33E-22 T 12-10-2018 VAPA_1c40680 33e020044c3886590ba2f8ced4936550 277 Pfam PF09339 IclR helix-turn-helix domain 26 71 2.8E-11 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 VAPA_1c40680 33e020044c3886590ba2f8ced4936550 277 SMART SM00346 21 111 4.6E-7 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 VAPA_1c40680 33e020044c3886590ba2f8ced4936550 277 SUPERFAMILY SSF55781 79 265 4.77E-51 T 12-10-2018 VAPA_1c40680 33e020044c3886590ba2f8ced4936550 277 Gene3D G3DSA:1.10.10.10 17 91 1.0E-14 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c40680 33e020044c3886590ba2f8ced4936550 277 SUPERFAMILY SSF46785 24 93 2.88E-12 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c40680 33e020044c3886590ba2f8ced4936550 277 Pfam PF01614 Bacterial transcriptional regulator 139 262 5.6E-33 T 12-10-2018 IPR014757 Transcription regulator IclR, C-terminal VAPA_1c40680 33e020044c3886590ba2f8ced4936550 277 Gene3D G3DSA:3.30.450.40 94 270 1.6E-56 T 12-10-2018 IPR029016 GAF-like domain superfamily VAPA_2c11450 5afa946dc9ca6784d11595a8b96efef7 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 140 159 5.8E-14 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c11450 5afa946dc9ca6784d11595a8b96efef7 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 120 128 5.8E-14 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c11450 5afa946dc9ca6784d11595a8b96efef7 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 67 78 5.8E-14 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c11450 5afa946dc9ca6784d11595a8b96efef7 255 Pfam PF00106 short chain dehydrogenase 2 176 2.9E-44 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c11450 5afa946dc9ca6784d11595a8b96efef7 255 Gene3D G3DSA:3.40.50.720 1 253 1.3E-60 T 12-10-2018 VAPA_2c11450 5afa946dc9ca6784d11595a8b96efef7 255 SUPERFAMILY SSF51735 1 240 4.32E-59 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_2c11450 5afa946dc9ca6784d11595a8b96efef7 255 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 127 155 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 VAPA_2c11450 5afa946dc9ca6784d11595a8b96efef7 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 7.8E-21 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c11450 5afa946dc9ca6784d11595a8b96efef7 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 114 130 7.8E-21 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c11450 5afa946dc9ca6784d11595a8b96efef7 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 140 159 7.8E-21 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c11450 5afa946dc9ca6784d11595a8b96efef7 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 67 78 7.8E-21 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c41460 5b37b7d9033d0e34bf59296b498d7e5f 454 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 357 448 1.7E-7 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase VAPA_1c41460 5b37b7d9033d0e34bf59296b498d7e5f 454 Gene3D G3DSA:3.30.450.20 39 182 3.3E-46 T 12-10-2018 VAPA_1c41460 5b37b7d9033d0e34bf59296b498d7e5f 454 Gene3D G3DSA:3.30.565.10 318 448 1.1E-29 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_1c41460 5b37b7d9033d0e34bf59296b498d7e5f 454 SUPERFAMILY SSF55874 329 444 1.78E-15 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_1c41460 5b37b7d9033d0e34bf59296b498d7e5f 454 Pfam PF07730 Histidine kinase 249 316 8.6E-15 T 12-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 VAPA_1c41460 5b37b7d9033d0e34bf59296b498d7e5f 454 Pfam PF17200 Single Cache domain 2 46 190 4.5E-42 T 12-10-2018 IPR033480 Single Cache domain 2 VAPA_1c41460 5b37b7d9033d0e34bf59296b498d7e5f 454 SMART SM01049 42 132 7.4E-34 T 12-10-2018 IPR033480 Single Cache domain 2 VAPA_1c41460 5b37b7d9033d0e34bf59296b498d7e5f 454 SMART SM00387 354 450 2.9E-7 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase VAPA_1c41460 5b37b7d9033d0e34bf59296b498d7e5f 454 PIRSF PIRSF037314 1 454 9.3E-177 T 12-10-2018 IPR017171 Signal transduction histidine kinase, MctS VAPA_2c06540 73dc7cbef4bbc4c02e0d596577381e2b 632 SMART SM00388 398 466 5.5E-6 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 VAPA_2c06540 73dc7cbef4bbc4c02e0d596577381e2b 632 SUPERFAMILY SSF55874 456 616 7.99E-38 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_2c06540 73dc7cbef4bbc4c02e0d596577381e2b 632 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 510 616 5.3E-20 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase VAPA_2c06540 73dc7cbef4bbc4c02e0d596577381e2b 632 Gene3D G3DSA:3.30.565.10 469 621 1.2E-38 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_2c06540 73dc7cbef4bbc4c02e0d596577381e2b 632 Gene3D G3DSA:1.10.287.130 377 461 6.3E-18 T 12-10-2018 VAPA_2c06540 73dc7cbef4bbc4c02e0d596577381e2b 632 PIRSF PIRSF036431 29 622 7.0E-174 T 12-10-2018 IPR017055 Signal transduction histidine kinase, DctB (C4-dicarboxylate transport system regulator) VAPA_2c06540 73dc7cbef4bbc4c02e0d596577381e2b 632 PRINTS PR00344 Bacterial sensor protein C-terminal signature 578 596 1.1E-14 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_2c06540 73dc7cbef4bbc4c02e0d596577381e2b 632 PRINTS PR00344 Bacterial sensor protein C-terminal signature 547 561 1.1E-14 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_2c06540 73dc7cbef4bbc4c02e0d596577381e2b 632 PRINTS PR00344 Bacterial sensor protein C-terminal signature 565 575 1.1E-14 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_2c06540 73dc7cbef4bbc4c02e0d596577381e2b 632 PRINTS PR00344 Bacterial sensor protein C-terminal signature 602 615 1.1E-14 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_2c06540 73dc7cbef4bbc4c02e0d596577381e2b 632 SUPERFAMILY SSF47384 395 462 6.47E-10 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 VAPA_2c06540 73dc7cbef4bbc4c02e0d596577381e2b 632 Gene3D G3DSA:3.30.450.20 81 313 1.8E-57 T 12-10-2018 VAPA_2c06540 73dc7cbef4bbc4c02e0d596577381e2b 632 SMART SM00387 508 618 3.3E-30 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase VAPA_2c06540 73dc7cbef4bbc4c02e0d596577381e2b 632 SUPERFAMILY SSF103190 92 225 2.07E-14 T 12-10-2018 IPR029151 Periplasmic sensor-like domain superfamily VAPA_2c06540 73dc7cbef4bbc4c02e0d596577381e2b 632 Pfam PF00512 His Kinase A (phospho-acceptor) domain 398 461 5.0E-8 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 VAPA_2c06540 73dc7cbef4bbc4c02e0d596577381e2b 632 Gene3D G3DSA:3.30.450.20 93 214 1.8E-57 T 12-10-2018 VAPA_1c49550 9b9f35f38ba1cf498d639d793115b7fc 285 PIRSF PIRSF036480 5 285 1.2E-110 T 12-10-2018 VAPA_1c49550 9b9f35f38ba1cf498d639d793115b7fc 285 SUPERFAMILY SSF55021 6 84 2.5E-16 T 12-10-2018 VAPA_1c49550 9b9f35f38ba1cf498d639d793115b7fc 285 Pfam PF00551 Formyl transferase 89 266 1.3E-39 T 12-10-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 VAPA_1c49550 9b9f35f38ba1cf498d639d793115b7fc 285 Pfam PF01842 ACT domain 8 67 7.5E-8 T 12-10-2018 IPR002912 ACT domain VAPA_1c49550 9b9f35f38ba1cf498d639d793115b7fc 285 Hamap MF_01927 Formyltetrahydrofolate deformylase [purU]. 5 284 46.758 T 12-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 VAPA_1c49550 9b9f35f38ba1cf498d639d793115b7fc 285 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 236 258 3.6E-53 T 12-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 VAPA_1c49550 9b9f35f38ba1cf498d639d793115b7fc 285 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 90 112 3.6E-53 T 12-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 VAPA_1c49550 9b9f35f38ba1cf498d639d793115b7fc 285 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 112 139 3.6E-53 T 12-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 VAPA_1c49550 9b9f35f38ba1cf498d639d793115b7fc 285 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 42 54 3.6E-53 T 12-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 VAPA_1c49550 9b9f35f38ba1cf498d639d793115b7fc 285 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 258 283 3.6E-53 T 12-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 VAPA_1c49550 9b9f35f38ba1cf498d639d793115b7fc 285 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 10 36 3.6E-53 T 12-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 VAPA_1c49550 9b9f35f38ba1cf498d639d793115b7fc 285 Gene3D G3DSA:3.40.50.170 89 285 1.0E-70 T 12-10-2018 VAPA_1c49550 9b9f35f38ba1cf498d639d793115b7fc 285 Gene3D G3DSA:3.30.70.260 2 87 1.6E-25 T 12-10-2018 VAPA_1c49550 9b9f35f38ba1cf498d639d793115b7fc 285 TIGRFAM TIGR00655 PurU: formyltetrahydrofolate deformylase 9 284 5.6E-103 T 12-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 VAPA_1c49550 9b9f35f38ba1cf498d639d793115b7fc 285 SUPERFAMILY SSF53328 89 285 2.49E-61 T 12-10-2018 IPR036477 Formyl transferase, N-terminal domain superfamily GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 VAPA_1c50920 10e77591c5e5f0687b1d36888dc5793f 274 Gene3D G3DSA:2.40.50.140 1 114 2.4E-46 T 12-10-2018 VAPA_1c50920 10e77591c5e5f0687b1d36888dc5793f 274 Gene3D G3DSA:4.10.950.10 196 274 1.7E-34 T 12-10-2018 IPR014726 Ribosomal protein L2, domain 3 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VAPA_1c50920 10e77591c5e5f0687b1d36888dc5793f 274 Pfam PF00181 Ribosomal Proteins L2, RNA binding domain 42 117 7.2E-33 T 12-10-2018 IPR022666 Ribosomal Proteins L2, RNA binding domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 VAPA_1c50920 10e77591c5e5f0687b1d36888dc5793f 274 TIGRFAM TIGR01171 rplB_bact: ribosomal protein uL2 4 274 3.5E-124 T 12-10-2018 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 VAPA_1c50920 10e77591c5e5f0687b1d36888dc5793f 274 Hamap MF_01320_B 50S ribosomal protein L2 [rplB]. 1 273 44.867 T 12-10-2018 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 VAPA_1c50920 10e77591c5e5f0687b1d36888dc5793f 274 PIRSF PIRSF002158 6 274 1.0E-95 T 12-10-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 VAPA_1c50920 10e77591c5e5f0687b1d36888dc5793f 274 SUPERFAMILY SSF50249 3 124 1.71E-45 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold VAPA_1c50920 10e77591c5e5f0687b1d36888dc5793f 274 SMART SM01383 42 118 2.7E-41 T 12-10-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 VAPA_1c50920 10e77591c5e5f0687b1d36888dc5793f 274 Gene3D G3DSA:2.30.30.30 118 195 4.3E-32 T 12-10-2018 IPR014722 Ribosomal protein L2, domain 2 VAPA_1c50920 10e77591c5e5f0687b1d36888dc5793f 274 Pfam PF03947 Ribosomal Proteins L2, C-terminal domain 126 250 1.7E-55 T 12-10-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 VAPA_1c50920 10e77591c5e5f0687b1d36888dc5793f 274 SMART SM01382 124 252 2.7E-87 T 12-10-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 VAPA_1c50920 10e77591c5e5f0687b1d36888dc5793f 274 ProSitePatterns PS00467 Ribosomal protein L2 signature. 218 229 - T 12-10-2018 IPR022671 Ribosomal protein L2, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VAPA_1c50920 10e77591c5e5f0687b1d36888dc5793f 274 SUPERFAMILY SSF50104 127 272 6.02E-59 T 12-10-2018 IPR008991 Translation protein SH3-like domain superfamily VAPA_1c10150 2ccb749213e544da282a8ecfcf663f0b 379 Pfam PF13671 AAA domain 238 364 1.1E-11 T 12-10-2018 VAPA_1c10150 2ccb749213e544da282a8ecfcf663f0b 379 SUPERFAMILY SSF109604 41 177 1.67E-12 T 12-10-2018 VAPA_1c10150 2ccb749213e544da282a8ecfcf663f0b 379 Gene3D G3DSA:3.40.50.300 232 379 2.0E-22 T 12-10-2018 VAPA_1c10150 2ccb749213e544da282a8ecfcf663f0b 379 SUPERFAMILY SSF52540 233 363 4.31E-10 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c10150 2ccb749213e544da282a8ecfcf663f0b 379 Gene3D G3DSA:1.10.3210.10 34 197 1.7E-6 T 12-10-2018 VAPA_2c08980 dccc1659cd2de702fdf900ac29734be2 205 Pfam PF00043 Glutathione S-transferase, C-terminal domain 124 183 1.3E-4 T 12-10-2018 IPR004046 Glutathione S-transferase, C-terminal VAPA_2c08980 dccc1659cd2de702fdf900ac29734be2 205 SUPERFAMILY SSF52833 1 80 2.38E-17 T 12-10-2018 IPR036249 Thioredoxin-like superfamily VAPA_2c08980 dccc1659cd2de702fdf900ac29734be2 205 Gene3D G3DSA:1.20.1050.10 79 190 2.4E-64 T 12-10-2018 VAPA_2c08980 dccc1659cd2de702fdf900ac29734be2 205 Pfam PF13417 Glutathione S-transferase, N-terminal domain 15 75 2.3E-8 T 12-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 VAPA_2c08980 dccc1659cd2de702fdf900ac29734be2 205 Gene3D G3DSA:3.40.30.10 2 197 2.4E-64 T 12-10-2018 VAPA_2c08980 dccc1659cd2de702fdf900ac29734be2 205 SUPERFAMILY SSF47616 68 198 2.65E-20 T 12-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily VAPA_1c18110 7f4034bb17d9672715dc387781f893e5 427 PIRSF PIRSF006066 1 427 9.5E-167 T 12-10-2018 IPR004681 TRAP transporter large membrane protein DctM GO:0016021 VAPA_1c18110 7f4034bb17d9672715dc387781f893e5 427 TIGRFAM TIGR00786 dctM: TRAP transporter, DctM subunit 17 422 1.4E-129 T 12-10-2018 IPR004681 TRAP transporter large membrane protein DctM GO:0016021 VAPA_1c18110 7f4034bb17d9672715dc387781f893e5 427 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 7 417 2.4E-113 T 12-10-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit VAPA_1c50900 c99f6c196b85e604eba78f9fe92ead40 110 Pfam PF00237 Ribosomal protein L22p/L17e 7 108 3.0E-35 T 12-10-2018 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 VAPA_1c50900 c99f6c196b85e604eba78f9fe92ead40 110 ProSitePatterns PS00464 Ribosomal protein L22 signature. 84 108 - T 12-10-2018 IPR018260 Ribosomal protein L22/L17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VAPA_1c50900 c99f6c196b85e604eba78f9fe92ead40 110 SUPERFAMILY SSF54843 4 109 6.93E-39 T 12-10-2018 IPR036394 Ribosomal protein L22/L17 superfamily GO:0003735|GO:0005840|GO:0006412 VAPA_1c50900 c99f6c196b85e604eba78f9fe92ead40 110 Gene3D G3DSA:3.90.470.10 1 110 4.1E-42 T 12-10-2018 IPR036394 Ribosomal protein L22/L17 superfamily GO:0003735|GO:0005840|GO:0006412 VAPA_1c50900 c99f6c196b85e604eba78f9fe92ead40 110 Hamap MF_01331_B 50S ribosomal protein L22 [rplV]. 2 110 24.589 T 12-10-2018 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 VAPA_1c50900 c99f6c196b85e604eba78f9fe92ead40 110 TIGRFAM TIGR01044 rplV_bact: ribosomal protein uL22 6 108 4.2E-44 T 12-10-2018 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 VAPA_1c01730 8cb83947bc4da66783f38d14e13af128 482 SMART SM01230 137 401 2.2E-78 T 12-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 VAPA_1c01730 8cb83947bc4da66783f38d14e13af128 482 Pfam PF00120 Glutamine synthetase, catalytic domain 139 478 1.2E-79 T 12-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 VAPA_1c01730 8cb83947bc4da66783f38d14e13af128 482 SUPERFAMILY SSF54368 23 136 9.55E-14 T 12-10-2018 IPR036651 Glutamine synthetase, N-terminal domain superfamily GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 VAPA_1c01730 8cb83947bc4da66783f38d14e13af128 482 SUPERFAMILY SSF55931 138 480 7.55E-89 T 12-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 VAPA_1c01730 8cb83947bc4da66783f38d14e13af128 482 Gene3D G3DSA:3.10.20.70 19 138 1.5E-9 T 12-10-2018 IPR036651 Glutamine synthetase, N-terminal domain superfamily GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 VAPA_1c01730 8cb83947bc4da66783f38d14e13af128 482 Gene3D G3DSA:3.30.590.10 140 482 3.4E-94 T 12-10-2018 VAPA_1c28170 4af2532348d817ed75d7a3c771e98eb3 611 Gene3D G3DSA:3.40.190.10 35 605 2.2E-216 T 12-10-2018 VAPA_1c28170 4af2532348d817ed75d7a3c771e98eb3 611 SUPERFAMILY SSF53850 56 605 5.76E-113 T 12-10-2018 VAPA_1c28170 4af2532348d817ed75d7a3c771e98eb3 611 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 108 516 8.8E-79 T 12-10-2018 IPR000914 Solute-binding protein family 5 domain VAPA_1c28170 4af2532348d817ed75d7a3c771e98eb3 611 Gene3D G3DSA:3.10.105.10 322 580 2.2E-216 T 12-10-2018 VAPA_1c28170 4af2532348d817ed75d7a3c771e98eb3 611 PIRSF PIRSF002741 6 586 1.8E-89 T 12-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 VAPA_2c11530 ac9e9a8902356bd9b292f236e19f0ac9 260 SUPERFAMILY SSF64288 80 256 1.08E-31 T 12-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily VAPA_2c11530 ac9e9a8902356bd9b292f236e19f0ac9 260 TIGRFAM TIGR02325 C_P_lyase_phnF: phosphonate metabolism transcriptional regulator PhnF 22 257 4.1E-59 T 12-10-2018 IPR012702 Phosphonate C-P lyase system, transcriptional regulator PhnF VAPA_2c11530 ac9e9a8902356bd9b292f236e19f0ac9 260 SMART SM00345 33 92 2.1E-22 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_2c11530 ac9e9a8902356bd9b292f236e19f0ac9 260 Pfam PF07702 UTRA domain 118 252 9.4E-25 T 12-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 VAPA_2c11530 ac9e9a8902356bd9b292f236e19f0ac9 260 Gene3D G3DSA:1.10.10.10 22 96 1.5E-22 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_2c11530 ac9e9a8902356bd9b292f236e19f0ac9 260 Pfam PF00392 Bacterial regulatory proteins, gntR family 32 92 1.5E-20 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_2c11530 ac9e9a8902356bd9b292f236e19f0ac9 260 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 52 66 1.7E-9 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_2c11530 ac9e9a8902356bd9b292f236e19f0ac9 260 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 66 82 1.7E-9 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_2c11530 ac9e9a8902356bd9b292f236e19f0ac9 260 SUPERFAMILY SSF46785 24 103 3.5E-21 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_2c11530 ac9e9a8902356bd9b292f236e19f0ac9 260 Gene3D G3DSA:3.40.1410.10 104 259 3.4E-29 T 12-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily VAPA_2c11530 ac9e9a8902356bd9b292f236e19f0ac9 260 SMART SM00866 113 253 1.1E-23 T 12-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 VAPA_1c29760 2fae52bc868cca7f29897beb48aee85a 1164 Gene3D G3DSA:3.30.2060.10 127 212 4.7E-113 T 12-10-2018 VAPA_1c29760 2fae52bc868cca7f29897beb48aee85a 1164 SMART SM00487 609 799 6.3E-30 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain VAPA_1c29760 2fae52bc868cca7f29897beb48aee85a 1164 Gene3D G3DSA:3.40.50.300 551 790 1.8E-226 T 12-10-2018 VAPA_1c29760 2fae52bc868cca7f29897beb48aee85a 1164 SUPERFAMILY SSF143517 1004 1154 2.48E-40 T 12-10-2018 IPR037235 TRCF-like, C-terminal domain VAPA_1c29760 2fae52bc868cca7f29897beb48aee85a 1164 SUPERFAMILY SSF52540 532 792 5.14E-57 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c29760 2fae52bc868cca7f29897beb48aee85a 1164 Gene3D G3DSA:2.30.30.840 484 550 1.8E-226 T 12-10-2018 VAPA_1c29760 2fae52bc868cca7f29897beb48aee85a 1164 Hamap MF_00969 Transcription-repair-coupling factor [mfd]. 32 1118 26.795 T 12-10-2018 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 VAPA_1c29760 2fae52bc868cca7f29897beb48aee85a 1164 Pfam PF00270 DEAD/DEAH box helicase 614 771 7.6E-18 T 12-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 VAPA_1c29760 2fae52bc868cca7f29897beb48aee85a 1164 Pfam PF02559 CarD-like/TRCF domain 481 584 1.3E-24 T 12-10-2018 IPR003711 CarD-like/TRCF domain VAPA_1c29760 2fae52bc868cca7f29897beb48aee85a 1164 SUPERFAMILY SSF52540 792 999 3.47E-46 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c29760 2fae52bc868cca7f29897beb48aee85a 1164 SUPERFAMILY SSF52540 353 464 5.04E-21 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c29760 2fae52bc868cca7f29897beb48aee85a 1164 Pfam PF00271 Helicase conserved C-terminal domain 815 918 1.0E-16 T 12-10-2018 IPR001650 Helicase, C-terminal VAPA_1c29760 2fae52bc868cca7f29897beb48aee85a 1164 Gene3D G3DSA:3.40.50.11180 20 330 4.7E-113 T 12-10-2018 VAPA_1c29760 2fae52bc868cca7f29897beb48aee85a 1164 SUPERFAMILY SSF141259 472 557 3.66E-20 T 12-10-2018 IPR036101 CarD-like/TRCF domain superfamily VAPA_1c29760 2fae52bc868cca7f29897beb48aee85a 1164 SUPERFAMILY SSF52540 9 335 1.79E-93 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c29760 2fae52bc868cca7f29897beb48aee85a 1164 TIGRFAM TIGR00580 mfd: transcription-repair coupling factor 146 1090 0.0 T 12-10-2018 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 VAPA_1c29760 2fae52bc868cca7f29897beb48aee85a 1164 SMART SM00490 835 919 3.1E-16 T 12-10-2018 IPR001650 Helicase, C-terminal VAPA_1c29760 2fae52bc868cca7f29897beb48aee85a 1164 SMART SM01058 480 585 1.4E-45 T 12-10-2018 IPR003711 CarD-like/TRCF domain VAPA_1c29760 2fae52bc868cca7f29897beb48aee85a 1164 Pfam PF03461 TRCF domain 1018 1109 3.7E-25 T 12-10-2018 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 VAPA_1c29760 2fae52bc868cca7f29897beb48aee85a 1164 Gene3D G3DSA:3.40.50.300 479 999 1.8E-226 T 12-10-2018 VAPA_1c29760 2fae52bc868cca7f29897beb48aee85a 1164 Gene3D G3DSA:3.40.50.11140 353 452 1.4E-9 T 12-10-2018 VAPA_1c29760 2fae52bc868cca7f29897beb48aee85a 1164 Gene3D G3DSA:3.90.1150.50 1013 1158 2.7E-40 T 12-10-2018 IPR037235 TRCF-like, C-terminal domain VAPA_1c29760 2fae52bc868cca7f29897beb48aee85a 1164 SMART SM00982 1017 1117 1.8E-46 T 12-10-2018 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 VAPA_1c37540 92b12a2004efcc673725c8cfdc098a90 126 Pfam PF00072 Response regulator receiver domain 7 117 1.2E-16 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_1c37540 92b12a2004efcc673725c8cfdc098a90 126 SMART SM00448 3 118 3.0E-15 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_1c37540 92b12a2004efcc673725c8cfdc098a90 126 SUPERFAMILY SSF52172 5 122 1.21E-21 T 12-10-2018 IPR011006 CheY-like superfamily VAPA_1c37540 92b12a2004efcc673725c8cfdc098a90 126 Gene3D G3DSA:3.40.50.2300 2 126 2.4E-20 T 12-10-2018 VAPA_2c02580 617eb9814c03034bba514b89cc276af8 551 Gene3D G3DSA:3.40.50.300 5 268 1.9E-68 T 12-10-2018 VAPA_2c02580 617eb9814c03034bba514b89cc276af8 551 Gene3D G3DSA:3.40.50.300 269 549 5.4E-70 T 12-10-2018 VAPA_2c02580 617eb9814c03034bba514b89cc276af8 551 SUPERFAMILY SSF52540 288 516 6.86E-58 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_2c02580 617eb9814c03034bba514b89cc276af8 551 SMART SM00382 29 228 6.8E-16 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_2c02580 617eb9814c03034bba514b89cc276af8 551 SMART SM00382 304 496 6.3E-17 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_2c02580 617eb9814c03034bba514b89cc276af8 551 ProSitePatterns PS00211 ABC transporters family signature. 419 433 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_2c02580 617eb9814c03034bba514b89cc276af8 551 SUPERFAMILY SSF52540 5 250 4.84E-53 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_2c02580 617eb9814c03034bba514b89cc276af8 551 Pfam PF00005 ABC transporter 295 447 3.0E-27 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_2c02580 617eb9814c03034bba514b89cc276af8 551 Pfam PF00005 ABC transporter 20 178 4.1E-23 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c52610 fe2e6ea6d517b9dcd125a0fb11e318d3 415 Pfam PF07995 Glucose / Sorbosone dehydrogenase 162 336 8.9E-6 T 12-10-2018 IPR012938 Glucose/Sorbosone dehydrogenase VAPA_1c52610 fe2e6ea6d517b9dcd125a0fb11e318d3 415 Gene3D G3DSA:2.120.10.30 143 402 1.2E-17 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like VAPA_1c52610 fe2e6ea6d517b9dcd125a0fb11e318d3 415 SUPERFAMILY SSF50952 48 405 5.36E-19 T 12-10-2018 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 VAPA_2c07290 4b8c4e80b6c434053aead91d5c20de8f 233 SUPERFAMILY SSF161098 18 213 2.75E-37 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_2c07290 4b8c4e80b6c434053aead91d5c20de8f 233 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 18 122 6.4E-16 T 12-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 VAPA_2c07290 4b8c4e80b6c434053aead91d5c20de8f 233 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 49 228 8.4E-19 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 VAPA_2c07290 4b8c4e80b6c434053aead91d5c20de8f 233 Gene3D G3DSA:1.10.3720.10 13 229 7.8E-48 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c37600 910be7f370dff0e482d8557a0eb448da 220 Gene3D G3DSA:3.40.30.10 2 72 3.5E-16 T 12-10-2018 VAPA_1c37600 910be7f370dff0e482d8557a0eb448da 220 Pfam PF13417 Glutathione S-transferase, N-terminal domain 9 75 2.9E-15 T 12-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 VAPA_1c37600 910be7f370dff0e482d8557a0eb448da 220 SUPERFAMILY SSF47616 96 208 9.95E-14 T 12-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily VAPA_1c37600 910be7f370dff0e482d8557a0eb448da 220 Gene3D G3DSA:1.20.1050.10 73 199 2.0E-6 T 12-10-2018 VAPA_1c37600 910be7f370dff0e482d8557a0eb448da 220 Pfam PF13410 Glutathione S-transferase, C-terminal domain 134 190 1.1E-6 T 12-10-2018 VAPA_1c37600 910be7f370dff0e482d8557a0eb448da 220 SUPERFAMILY SSF52833 8 89 1.32E-17 T 12-10-2018 IPR036249 Thioredoxin-like superfamily VAPA_2c10430 340c525833a8b2a9a3d97c57b53540de 239 Gene3D G3DSA:3.40.50.300 1 237 5.8E-54 T 12-10-2018 VAPA_2c10430 340c525833a8b2a9a3d97c57b53540de 239 Pfam PF00005 ABC transporter 20 163 5.0E-26 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_2c10430 340c525833a8b2a9a3d97c57b53540de 239 SUPERFAMILY SSF52540 3 235 1.78E-53 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_2c10430 340c525833a8b2a9a3d97c57b53540de 239 SMART SM00382 28 203 6.3E-8 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_2c10430 340c525833a8b2a9a3d97c57b53540de 239 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 216 236 4.8E-6 T 12-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal VAPA_1c41760 b3a5c5fb61bfbb5e85331290bdb0dc59 443 Gene3D G3DSA:1.10.287.40 1 107 4.6E-19 T 12-10-2018 VAPA_1c41760 b3a5c5fb61bfbb5e85331290bdb0dc59 443 Gene3D G3DSA:3.30.930.10 108 441 6.1E-111 T 12-10-2018 VAPA_1c41760 b3a5c5fb61bfbb5e85331290bdb0dc59 443 SUPERFAMILY SSF55681 140 436 2.72E-94 T 12-10-2018 VAPA_1c41760 b3a5c5fb61bfbb5e85331290bdb0dc59 443 PRINTS PR00981 Seryl-tRNA synthetase signature 335 348 2.1E-32 T 12-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 VAPA_1c41760 b3a5c5fb61bfbb5e85331290bdb0dc59 443 PRINTS PR00981 Seryl-tRNA synthetase signature 352 368 2.1E-32 T 12-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 VAPA_1c41760 b3a5c5fb61bfbb5e85331290bdb0dc59 443 PRINTS PR00981 Seryl-tRNA synthetase signature 370 386 2.1E-32 T 12-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 VAPA_1c41760 b3a5c5fb61bfbb5e85331290bdb0dc59 443 PRINTS PR00981 Seryl-tRNA synthetase signature 295 308 2.1E-32 T 12-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 VAPA_1c41760 b3a5c5fb61bfbb5e85331290bdb0dc59 443 PRINTS PR00981 Seryl-tRNA synthetase signature 283 295 2.1E-32 T 12-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 VAPA_1c41760 b3a5c5fb61bfbb5e85331290bdb0dc59 443 Pfam PF02403 Seryl-tRNA synthetase N-terminal domain 1 110 9.2E-26 T 12-10-2018 IPR015866 Serine-tRNA synthetase, type1, N-terminal KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: R-HSA-2408557|Reactome: R-HSA-379716 VAPA_1c41760 b3a5c5fb61bfbb5e85331290bdb0dc59 443 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 243 418 3.9E-37 T 12-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 VAPA_1c41760 b3a5c5fb61bfbb5e85331290bdb0dc59 443 SUPERFAMILY SSF46589 1 115 5.75E-25 T 12-10-2018 IPR010978 Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm GO:0000166 VAPA_1c41760 b3a5c5fb61bfbb5e85331290bdb0dc59 443 Hamap MF_00176 Serine--tRNA ligase [serS]. 1 440 39.165 T 12-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 VAPA_1c41760 b3a5c5fb61bfbb5e85331290bdb0dc59 443 TIGRFAM TIGR00414 serS: serine--tRNA ligase 1 435 2.9E-156 T 12-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 VAPA_1c41760 b3a5c5fb61bfbb5e85331290bdb0dc59 443 PIRSF PIRSF001529 1 443 9.0E-169 T 12-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 VAPA_1c17480 bbc2c4737643642ceda9dfc328e47200 515 Gene3D G3DSA:3.30.565.10 218 379 2.8E-41 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_1c17480 bbc2c4737643642ceda9dfc328e47200 515 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 263 375 4.0E-27 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase VAPA_1c17480 bbc2c4737643642ceda9dfc328e47200 515 Pfam PF00512 His Kinase A (phospho-acceptor) domain 152 216 3.1E-15 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 VAPA_1c17480 bbc2c4737643642ceda9dfc328e47200 515 PRINTS PR00344 Bacterial sensor protein C-terminal signature 335 353 9.3E-16 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c17480 bbc2c4737643642ceda9dfc328e47200 515 PRINTS PR00344 Bacterial sensor protein C-terminal signature 360 373 9.3E-16 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c17480 bbc2c4737643642ceda9dfc328e47200 515 PRINTS PR00344 Bacterial sensor protein C-terminal signature 300 314 9.3E-16 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c17480 bbc2c4737643642ceda9dfc328e47200 515 PRINTS PR00344 Bacterial sensor protein C-terminal signature 318 328 9.3E-16 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c17480 bbc2c4737643642ceda9dfc328e47200 515 SUPERFAMILY SSF55874 206 376 3.54E-44 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_1c17480 bbc2c4737643642ceda9dfc328e47200 515 SMART SM00388 151 217 2.7E-17 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 VAPA_1c17480 bbc2c4737643642ceda9dfc328e47200 515 SUPERFAMILY SSF47384 137 218 4.51E-18 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 VAPA_1c17480 bbc2c4737643642ceda9dfc328e47200 515 SUPERFAMILY SSF52172 399 513 9.68E-29 T 12-10-2018 IPR011006 CheY-like superfamily VAPA_1c17480 bbc2c4737643642ceda9dfc328e47200 515 Gene3D G3DSA:1.10.287.130 139 217 8.4E-19 T 12-10-2018 VAPA_1c17480 bbc2c4737643642ceda9dfc328e47200 515 SMART SM00448 398 512 1.7E-25 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_1c17480 bbc2c4737643642ceda9dfc328e47200 515 SMART SM00387 263 376 3.9E-37 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase VAPA_1c17480 bbc2c4737643642ceda9dfc328e47200 515 Gene3D G3DSA:3.40.50.12740 397 514 4.0E-30 T 12-10-2018 VAPA_1c17480 bbc2c4737643642ceda9dfc328e47200 515 Pfam PF00072 Response regulator receiver domain 400 512 2.9E-19 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_1c51540 48c09ab4f4778544164f073369d3e5cd 316 SUPERFAMILY SSF52540 13 234 2.07E-64 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c51540 48c09ab4f4778544164f073369d3e5cd 316 SMART SM00382 38 229 1.3E-14 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c51540 48c09ab4f4778544164f073369d3e5cd 316 Pfam PF00005 ABC transporter 30 172 3.9E-30 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c51540 48c09ab4f4778544164f073369d3e5cd 316 Gene3D G3DSA:3.40.50.300 5 245 2.2E-68 T 12-10-2018 VAPA_1c51540 48c09ab4f4778544164f073369d3e5cd 316 ProSitePatterns PS00211 ABC transporters family signature. 145 159 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_1c00310 7211ea21530a82e9d5bb211f814bf2a7 747 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 161 742 2.2E-183 T 12-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 VAPA_1c00310 7211ea21530a82e9d5bb211f814bf2a7 747 PRINTS PR00943 Copper-transporting ATPase signature 614 631 5.7E-11 T 12-10-2018 VAPA_1c00310 7211ea21530a82e9d5bb211f814bf2a7 747 PRINTS PR00943 Copper-transporting ATPase signature 355 369 5.7E-11 T 12-10-2018 VAPA_1c00310 7211ea21530a82e9d5bb211f814bf2a7 747 PRINTS PR00943 Copper-transporting ATPase signature 222 240 5.7E-11 T 12-10-2018 VAPA_1c00310 7211ea21530a82e9d5bb211f814bf2a7 747 PRINTS PR00943 Copper-transporting ATPase signature 146 165 5.7E-11 T 12-10-2018 VAPA_1c00310 7211ea21530a82e9d5bb211f814bf2a7 747 PRINTS PR00943 Copper-transporting ATPase signature 202 221 5.7E-11 T 12-10-2018 VAPA_1c00310 7211ea21530a82e9d5bb211f814bf2a7 747 PRINTS PR00943 Copper-transporting ATPase signature 415 430 5.7E-11 T 12-10-2018 VAPA_1c00310 7211ea21530a82e9d5bb211f814bf2a7 747 ProSitePatterns PS01047 Heavy-metal-associated domain. 19 48 - T 12-10-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 VAPA_1c00310 7211ea21530a82e9d5bb211f814bf2a7 747 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 282 296 4.8E-24 T 12-10-2018 VAPA_1c00310 7211ea21530a82e9d5bb211f814bf2a7 747 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 432 446 4.8E-24 T 12-10-2018 VAPA_1c00310 7211ea21530a82e9d5bb211f814bf2a7 747 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 560 571 4.8E-24 T 12-10-2018 VAPA_1c00310 7211ea21530a82e9d5bb211f814bf2a7 747 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 637 656 4.8E-24 T 12-10-2018 VAPA_1c00310 7211ea21530a82e9d5bb211f814bf2a7 747 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 582 592 4.8E-24 T 12-10-2018 VAPA_1c00310 7211ea21530a82e9d5bb211f814bf2a7 747 SUPERFAMILY SSF56784 430 740 1.06E-54 T 12-10-2018 IPR036412 HAD-like superfamily VAPA_1c00310 7211ea21530a82e9d5bb211f814bf2a7 747 Gene3D G3DSA:3.40.1110.10 443 567 1.5E-81 T 12-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 VAPA_1c00310 7211ea21530a82e9d5bb211f814bf2a7 747 SUPERFAMILY SSF81653 235 332 7.32E-26 T 12-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 VAPA_1c00310 7211ea21530a82e9d5bb211f814bf2a7 747 Pfam PF00702 haloacid dehalogenase-like hydrolase 430 651 3.3E-43 T 12-10-2018 VAPA_1c00310 7211ea21530a82e9d5bb211f814bf2a7 747 Gene3D G3DSA:3.40.50.1000 413 692 1.5E-81 T 12-10-2018 IPR023214 HAD superfamily VAPA_1c00310 7211ea21530a82e9d5bb211f814bf2a7 747 Gene3D G3DSA:2.70.150.20 226 337 1.7E-37 T 12-10-2018 VAPA_1c00310 7211ea21530a82e9d5bb211f814bf2a7 747 SUPERFAMILY SSF55008 9 80 3.27E-18 T 12-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 VAPA_1c00310 7211ea21530a82e9d5bb211f814bf2a7 747 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 434 440 - T 12-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 VAPA_1c00310 7211ea21530a82e9d5bb211f814bf2a7 747 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 143 743 2.0E-166 T 12-10-2018 VAPA_1c00310 7211ea21530a82e9d5bb211f814bf2a7 747 SUPERFAMILY SSF81665 200 424 6.67E-13 T 12-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 VAPA_1c00310 7211ea21530a82e9d5bb211f814bf2a7 747 Pfam PF00122 E1-E2 ATPase 233 412 1.5E-54 T 12-10-2018 VAPA_1c00310 7211ea21530a82e9d5bb211f814bf2a7 747 Pfam PF00403 Heavy-metal-associated domain 17 78 1.0E-14 T 12-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 VAPA_1c00310 7211ea21530a82e9d5bb211f814bf2a7 747 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 205 459 2.1E-43 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 VAPA_1c00310 7211ea21530a82e9d5bb211f814bf2a7 747 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 555 723 1.1E-38 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 VAPA_1c00310 7211ea21530a82e9d5bb211f814bf2a7 747 Gene3D G3DSA:3.30.70.100 12 83 2.7E-20 T 12-10-2018 VAPA_1c36770 95c0ca5fb7d648a1746634df26255dc2 420 Gene3D G3DSA:1.20.1530.20 3 412 3.1E-94 T 12-10-2018 IPR038770 Sodium/solute symporter superfamily VAPA_1c36770 95c0ca5fb7d648a1746634df26255dc2 420 Pfam PF00999 Sodium/hydrogen exchanger family 11 401 5.8E-53 T 12-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 VAPA_2c02540 aa67679cb7bebf4c3e0b0d8d6302a967 232 SUPERFAMILY SSF51366 3 227 4.71E-58 T 12-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 VAPA_2c02540 aa67679cb7bebf4c3e0b0d8d6302a967 232 SMART SM00934 4 224 7.6E-65 T 12-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 VAPA_2c02540 aa67679cb7bebf4c3e0b0d8d6302a967 232 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 3 222 1.5E-36 T 12-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 VAPA_2c02540 aa67679cb7bebf4c3e0b0d8d6302a967 232 Gene3D G3DSA:3.20.20.70 2 230 4.5E-71 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 VAPA_2c02540 aa67679cb7bebf4c3e0b0d8d6302a967 232 TIGRFAM TIGR01740 pyrF: orotidine 5'-phosphate decarboxylase 6 224 3.2E-48 T 12-10-2018 IPR014732 Orotidine 5'-phosphate decarboxylase GO:0004590|GO:0044205 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 VAPA_2c02540 aa67679cb7bebf4c3e0b0d8d6302a967 232 Hamap MF_01200_B Orotidine 5'-phosphate decarboxylase [pyrF]. 2 229 30.771 T 12-10-2018 IPR014732 Orotidine 5'-phosphate decarboxylase GO:0004590|GO:0044205 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 VAPA_1c10020 d676ba2e9b756bc19b7c4a9da5cd76b4 449 SUPERFAMILY SSF56059 83 345 1.38E-69 T 12-10-2018 VAPA_1c10020 d676ba2e9b756bc19b7c4a9da5cd76b4 449 SUPERFAMILY SSF52440 1 113 2.95E-46 T 12-10-2018 IPR016185 Pre-ATP-grasp domain superfamily VAPA_1c10020 d676ba2e9b756bc19b7c4a9da5cd76b4 449 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 286 293 - T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 VAPA_1c10020 d676ba2e9b756bc19b7c4a9da5cd76b4 449 SMART SM00878 336 441 9.6E-64 T 12-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 VAPA_1c10020 d676ba2e9b756bc19b7c4a9da5cd76b4 449 Gene3D G3DSA:3.40.50.20 1 85 1.6E-33 T 12-10-2018 VAPA_1c10020 d676ba2e9b756bc19b7c4a9da5cd76b4 449 Gene3D G3DSA:3.30.1490.20 131 203 2.3E-151 T 12-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 VAPA_1c10020 d676ba2e9b756bc19b7c4a9da5cd76b4 449 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 115 322 9.5E-79 T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 VAPA_1c10020 d676ba2e9b756bc19b7c4a9da5cd76b4 449 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 154 168 - T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 VAPA_1c10020 d676ba2e9b756bc19b7c4a9da5cd76b4 449 Gene3D G3DSA:3.30.470.20 87 433 2.3E-151 T 12-10-2018 VAPA_1c10020 d676ba2e9b756bc19b7c4a9da5cd76b4 449 TIGRFAM TIGR00514 accC: acetyl-CoA carboxylase, biotin carboxylase subunit 1 444 2.6E-225 T 12-10-2018 IPR004549 Acetyl-CoA carboxylase, biotin carboxylase GO:0016874 VAPA_1c10020 d676ba2e9b756bc19b7c4a9da5cd76b4 449 Pfam PF00289 Biotin carboxylase, N-terminal domain 1 109 1.1E-43 T 12-10-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 VAPA_1c10020 d676ba2e9b756bc19b7c4a9da5cd76b4 449 SUPERFAMILY SSF51246 331 444 1.99E-43 T 12-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 VAPA_1c10020 d676ba2e9b756bc19b7c4a9da5cd76b4 449 Pfam PF02785 Biotin carboxylase C-terminal domain 336 442 2.5E-38 T 12-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 VAPA_1c22260 bf31618f87e483ead38ca9dac9bf356e 547 Pfam PF02954 Bacterial regulatory protein, Fis family 509 541 4.1E-9 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 VAPA_1c22260 bf31618f87e483ead38ca9dac9bf356e 547 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 435 444 - T 12-10-2018 IPR025944 Sigma-54 interaction domain, conserved site VAPA_1c22260 bf31618f87e483ead38ca9dac9bf356e 547 SMART SM00065 40 200 1.2E-13 T 12-10-2018 IPR003018 GAF domain GO:0005515 VAPA_1c22260 bf31618f87e483ead38ca9dac9bf356e 547 Pfam PF01590 GAF domain 42 185 2.7E-11 T 12-10-2018 IPR003018 GAF domain GO:0005515 VAPA_1c22260 bf31618f87e483ead38ca9dac9bf356e 547 Gene3D G3DSA:3.40.50.300 211 393 8.0E-65 T 12-10-2018 VAPA_1c22260 bf31618f87e483ead38ca9dac9bf356e 547 Pfam PF00158 Sigma-54 interaction domain 223 389 4.9E-70 T 12-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 VAPA_1c22260 bf31618f87e483ead38ca9dac9bf356e 547 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 507 524 1.5E-5 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 VAPA_1c22260 bf31618f87e483ead38ca9dac9bf356e 547 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 524 544 1.5E-5 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 VAPA_1c22260 bf31618f87e483ead38ca9dac9bf356e 547 SUPERFAMILY SSF55781 42 200 3.71E-17 T 12-10-2018 VAPA_1c22260 bf31618f87e483ead38ca9dac9bf356e 547 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 247 260 - T 12-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 VAPA_1c22260 bf31618f87e483ead38ca9dac9bf356e 547 Gene3D G3DSA:1.10.8.60 394 469 5.3E-22 T 12-10-2018 VAPA_1c22260 bf31618f87e483ead38ca9dac9bf356e 547 SUPERFAMILY SSF52540 222 464 5.59E-70 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c22260 bf31618f87e483ead38ca9dac9bf356e 547 SMART SM00382 243 386 5.0E-9 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c22260 bf31618f87e483ead38ca9dac9bf356e 547 Gene3D G3DSA:3.30.450.40 21 202 5.5E-34 T 12-10-2018 IPR029016 GAF-like domain superfamily VAPA_2c00320 11f8e32571ad075646101239cb6155e7 238 SUPERFAMILY SSF53448 3 232 1.08E-25 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases VAPA_2c00320 11f8e32571ad075646101239cb6155e7 238 Gene3D G3DSA:3.90.550.10 2 236 2.1E-55 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases VAPA_2c00320 11f8e32571ad075646101239cb6155e7 238 Pfam PF12804 MobA-like NTP transferase domain 8 112 1.8E-7 T 12-10-2018 IPR025877 MobA-like NTP transferase VAPA_2c00320 11f8e32571ad075646101239cb6155e7 238 PIRSF PIRSF028162 1 236 7.6E-79 T 12-10-2018 IPR016873 Capsular polysaccharide biosynthesis protein, BcbE, predicted VAPA_1c22430 ec2b7a6a28e0bf575ed940eed7ca0c11 364 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 225 234 - T 12-10-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0016740 VAPA_1c22430 ec2b7a6a28e0bf575ed940eed7ca0c11 364 Pfam PF00155 Aminotransferase class I and II 37 360 1.9E-51 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 VAPA_1c22430 ec2b7a6a28e0bf575ed940eed7ca0c11 364 Gene3D G3DSA:3.90.1150.10 14 357 1.3E-98 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 VAPA_1c22430 ec2b7a6a28e0bf575ed940eed7ca0c11 364 TIGRFAM TIGR01141 hisC: histidinol-phosphate transaminase 9 360 1.0E-84 T 12-10-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 VAPA_1c22430 ec2b7a6a28e0bf575ed940eed7ca0c11 364 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 6 364 50.665 T 12-10-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 VAPA_1c22430 ec2b7a6a28e0bf575ed940eed7ca0c11 364 Gene3D G3DSA:3.40.640.10 49 273 1.3E-98 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 VAPA_1c22430 ec2b7a6a28e0bf575ed940eed7ca0c11 364 SUPERFAMILY SSF53383 15 360 2.3E-74 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase VAPA_1c40970 2cdf078937bec04fe343eba949e9ca5c 767 Gene3D G3DSA:3.40.50.10750 581 735 9.1E-85 T 12-10-2018 VAPA_1c40970 2cdf078937bec04fe343eba949e9ca5c 767 Pfam PF01515 Phosphate acetyl/butaryl transferase 436 759 9.4E-86 T 12-10-2018 IPR002505 Phosphate acetyl/butaryl transferase GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 VAPA_1c40970 2cdf078937bec04fe343eba949e9ca5c 767 PIRSF PIRSF036684 6 767 0.0 T 12-10-2018 IPR012188 NAD(P)-dependent malic enzyme GO:0004470|GO:0006108|GO:0046872 KEGG: 00620+1.1.1.40|KEGG: 00710+1.1.1.40|MetaCyc: PWY-241|MetaCyc: PWY-7117 VAPA_1c40970 2cdf078937bec04fe343eba949e9ca5c 767 SUPERFAMILY SSF53223 18 168 7.19E-52 T 12-10-2018 VAPA_1c40970 2cdf078937bec04fe343eba949e9ca5c 767 Pfam PF00390 Malic enzyme, N-terminal domain 26 158 2.0E-25 T 12-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 VAPA_1c40970 2cdf078937bec04fe343eba949e9ca5c 767 SUPERFAMILY SSF53659 436 762 9.46E-89 T 12-10-2018 VAPA_1c40970 2cdf078937bec04fe343eba949e9ca5c 767 Gene3D G3DSA:3.40.50.10950 454 758 9.1E-85 T 12-10-2018 VAPA_1c40970 2cdf078937bec04fe343eba949e9ca5c 767 ProSitePatterns PS00331 Malic enzymes signature. 166 182 - T 12-10-2018 IPR015884 Malic enzyme, conserved site GO:0004471|GO:0055114 VAPA_1c40970 2cdf078937bec04fe343eba949e9ca5c 767 SMART SM00919 170 408 2.0E-133 T 12-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 VAPA_1c40970 2cdf078937bec04fe343eba949e9ca5c 767 SUPERFAMILY SSF51735 170 460 6.54E-84 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c40970 2cdf078937bec04fe343eba949e9ca5c 767 SMART SM01274 25 158 9.4E-78 T 12-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 VAPA_1c40970 2cdf078937bec04fe343eba949e9ca5c 767 Gene3D G3DSA:3.40.50.10380 7 167 6.0E-67 T 12-10-2018 IPR037062 Malic enzyme, N-terminal domain superfamily GO:0004471|GO:0055114 VAPA_1c40970 2cdf078937bec04fe343eba949e9ca5c 767 Pfam PF03949 Malic enzyme, NAD binding domain 172 367 3.6E-22 T 12-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 VAPA_1c40970 2cdf078937bec04fe343eba949e9ca5c 767 Gene3D G3DSA:3.40.50.720 168 453 5.1E-80 T 12-10-2018 VAPA_1c16890 78ccd93b1f2fea87c074128e81a0da73 794 Gene3D G3DSA:3.90.1170.50 3 145 4.2E-46 T 12-10-2018 VAPA_1c16890 78ccd93b1f2fea87c074128e81a0da73 794 SUPERFAMILY SSF56003 137 789 1.83E-195 T 12-10-2018 IPR037165 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain superfamily GO:0016491|GO:0055114 VAPA_1c16890 78ccd93b1f2fea87c074128e81a0da73 794 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 26 145 3.6E-29 T 12-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead VAPA_1c16890 78ccd93b1f2fea87c074128e81a0da73 794 Gene3D G3DSA:3.30.365.10 444 786 2.3E-137 T 12-10-2018 VAPA_1c16890 78ccd93b1f2fea87c074128e81a0da73 794 Gene3D G3DSA:3.30.365.10 203 300 7.8E-61 T 12-10-2018 VAPA_1c16890 78ccd93b1f2fea87c074128e81a0da73 794 Gene3D G3DSA:3.30.365.10 161 377 7.8E-61 T 12-10-2018 VAPA_1c16890 78ccd93b1f2fea87c074128e81a0da73 794 SUPERFAMILY SSF54665 7 159 5.76E-47 T 12-10-2018 IPR036856 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead superfamily VAPA_1c16890 78ccd93b1f2fea87c074128e81a0da73 794 Gene3D G3DSA:3.30.365.10 471 640 2.3E-137 T 12-10-2018 VAPA_1c16890 78ccd93b1f2fea87c074128e81a0da73 794 SMART SM01008 26 145 3.2E-56 T 12-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead VAPA_1c16890 78ccd93b1f2fea87c074128e81a0da73 794 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 162 726 8.4E-172 T 12-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 VAPA_1c21210 37269e43486d80d56d25cde3605a0a80 152 Pfam PF09278 MerR, DNA binding 48 107 1.3E-13 T 12-10-2018 IPR015358 Transcription regulator MerR, DNA binding VAPA_1c21210 37269e43486d80d56d25cde3605a0a80 152 Gene3D G3DSA:1.10.1660.10 2 123 2.0E-25 T 12-10-2018 VAPA_1c21210 37269e43486d80d56d25cde3605a0a80 152 SMART SM00422 6 74 1.5E-13 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 VAPA_1c21210 37269e43486d80d56d25cde3605a0a80 152 SUPERFAMILY SSF46955 7 125 2.31E-24 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily VAPA_1c21210 37269e43486d80d56d25cde3605a0a80 152 Pfam PF00376 MerR family regulatory protein 8 43 9.6E-11 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 VAPA_1c21210 37269e43486d80d56d25cde3605a0a80 152 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 41 61 3.9E-6 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 VAPA_1c21210 37269e43486d80d56d25cde3605a0a80 152 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 18 31 3.9E-6 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 VAPA_1c21210 37269e43486d80d56d25cde3605a0a80 152 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 7 18 3.9E-6 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 VAPA_2c11350 c043fd541f685d0c8f14f2d1c904999f 388 Pfam PF13458 Periplasmic binding protein 44 342 8.1E-55 T 12-10-2018 IPR028081 Leucine-binding protein domain VAPA_2c11350 c043fd541f685d0c8f14f2d1c904999f 388 Gene3D G3DSA:3.40.50.2300 158 294 2.0E-71 T 12-10-2018 VAPA_2c11350 c043fd541f685d0c8f14f2d1c904999f 388 Gene3D G3DSA:3.40.50.2300 50 337 2.0E-71 T 12-10-2018 VAPA_2c11350 c043fd541f685d0c8f14f2d1c904999f 388 SUPERFAMILY SSF53822 44 338 2.53E-58 T 12-10-2018 IPR028082 Periplasmic binding protein-like I VAPA_2c09710 777554beb41b81a8aa4cac29c5b2aa75 425 Pfam PF00355 Rieske [2Fe-2S] domain 27 110 1.6E-17 T 12-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 VAPA_2c09710 777554beb41b81a8aa4cac29c5b2aa75 425 Gene3D G3DSA:2.102.10.10 23 154 1.2E-34 T 12-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 VAPA_2c09710 777554beb41b81a8aa4cac29c5b2aa75 425 SUPERFAMILY SSF55961 128 386 1.73E-39 T 12-10-2018 VAPA_2c09710 777554beb41b81a8aa4cac29c5b2aa75 425 SUPERFAMILY SSF50022 16 140 3.93E-32 T 12-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 VAPA_2c09710 777554beb41b81a8aa4cac29c5b2aa75 425 ProSitePatterns PS00570 Bacterial ring hydroxylating dioxygenases alpha-subunit signature. 70 92 - T 12-10-2018 IPR015881 Aromatic-ring-hydroxylating dioxygenase, 2Fe-2S-binding site GO:0005506|GO:0051537|GO:0055114 VAPA_1c21530 f267d55a65c0b0d0b532b104bb7c2cf0 245 Pfam PF00106 short chain dehydrogenase 4 196 5.9E-62 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c21530 f267d55a65c0b0d0b532b104bb7c2cf0 245 Gene3D G3DSA:3.40.50.720 1 245 1.0E-79 T 12-10-2018 VAPA_1c21530 f267d55a65c0b0d0b532b104bb7c2cf0 245 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 4 188 6.5E-6 T 12-10-2018 VAPA_1c21530 f267d55a65c0b0d0b532b104bb7c2cf0 245 SUPERFAMILY SSF51735 3 244 3.54E-76 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c21530 f267d55a65c0b0d0b532b104bb7c2cf0 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 79 90 5.6E-16 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c21530 f267d55a65c0b0d0b532b104bb7c2cf0 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 132 140 5.6E-16 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c21530 f267d55a65c0b0d0b532b104bb7c2cf0 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 152 171 5.6E-16 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c21530 f267d55a65c0b0d0b532b104bb7c2cf0 245 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 139 167 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 VAPA_1c21530 f267d55a65c0b0d0b532b104bb7c2cf0 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 152 171 2.3E-46 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c21530 f267d55a65c0b0d0b532b104bb7c2cf0 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 126 142 2.3E-46 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c21530 f267d55a65c0b0d0b532b104bb7c2cf0 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 2.3E-46 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c21530 f267d55a65c0b0d0b532b104bb7c2cf0 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 173 190 2.3E-46 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c21530 f267d55a65c0b0d0b532b104bb7c2cf0 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 2.3E-46 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c21530 f267d55a65c0b0d0b532b104bb7c2cf0 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 206 226 2.3E-46 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c21530 f267d55a65c0b0d0b532b104bb7c2cf0 245 TIGRFAM TIGR01829 AcAcCoA_reduct: acetoacetyl-CoA reductase 4 244 8.6E-115 T 12-10-2018 IPR011283 Acetoacetyl-CoA reductase GO:0005737|GO:0018454|GO:0042619|GO:0055114 KEGG: 00630+1.1.1.36|KEGG: 00650+1.1.1.36|MetaCyc: PWY-5676|MetaCyc: PWY-5741|MetaCyc: PWY-7216|MetaCyc: PWY-7948 VAPA_1c00790 b08b555971eecbffd3d60b7fe40c8348 314 SUPERFAMILY SSF51735 7 184 4.76E-47 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c00790 b08b555971eecbffd3d60b7fe40c8348 314 SUPERFAMILY SSF48179 187 278 1.79E-15 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 VAPA_1c00790 b08b555971eecbffd3d60b7fe40c8348 314 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 9 182 7.7E-48 T 12-10-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 VAPA_1c00790 b08b555971eecbffd3d60b7fe40c8348 314 Gene3D G3DSA:3.40.50.720 5 187 1.5E-54 T 12-10-2018 VAPA_1c00790 b08b555971eecbffd3d60b7fe40c8348 314 Gene3D G3DSA:1.10.1040.10 188 311 1.4E-36 T 12-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 VAPA_1c00790 b08b555971eecbffd3d60b7fe40c8348 314 PIRSF PIRSF000105 1 307 8.8E-71 T 12-10-2018 IPR022694 3-hydroxyacyl-CoA dehydrogenase GO:0003857|GO:0006631|GO:0055114|GO:0070403 VAPA_1c00790 b08b555971eecbffd3d60b7fe40c8348 314 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 187 255 1.1E-13 T 12-10-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 VAPA_1c14590 2d1fe79fc866d3dd9c8e0828e9e4d697 393 Gene3D G3DSA:1.20.1250.20 1 170 2.2E-26 T 12-10-2018 VAPA_1c14590 2d1fe79fc866d3dd9c8e0828e9e4d697 393 Gene3D G3DSA:1.20.1250.20 185 387 3.2E-16 T 12-10-2018 VAPA_1c14590 2d1fe79fc866d3dd9c8e0828e9e4d697 393 Pfam PF07690 Major Facilitator Superfamily 4 340 3.2E-32 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 VAPA_1c14590 2d1fe79fc866d3dd9c8e0828e9e4d697 393 SUPERFAMILY SSF103473 2 385 1.57E-47 T 12-10-2018 IPR036259 MFS transporter superfamily VAPA_1c30010 e6bee576bc03273a97df84910ddff8cc 336 Gene3D G3DSA:1.10.3470.10 5 333 6.5E-79 T 12-10-2018 IPR037294 ABC transporter, BtuC-like VAPA_1c30010 e6bee576bc03273a97df84910ddff8cc 336 Pfam PF01032 FecCD transport family 23 328 1.8E-73 T 12-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 VAPA_1c30010 e6bee576bc03273a97df84910ddff8cc 336 SUPERFAMILY SSF81345 4 329 1.44E-68 T 12-10-2018 IPR037294 ABC transporter, BtuC-like VAPA_1c45730 cb0b1d1d99336ff53fb384fc5c89b6c8 621 Pfam PF02254 TrkA-N domain 409 521 1.8E-23 T 12-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 VAPA_1c45730 cb0b1d1d99336ff53fb384fc5c89b6c8 621 Gene3D G3DSA:3.40.50.720 405 566 1.2E-38 T 12-10-2018 VAPA_1c45730 cb0b1d1d99336ff53fb384fc5c89b6c8 621 TIGRFAM TIGR00932 2a37: transporter, monovalent cation:proton antiporter-2 (CPA2) family 16 290 6.1E-83 T 12-10-2018 IPR004771 K+/H+ exchanger GO:0006812|GO:0008324|GO:0016021 VAPA_1c45730 cb0b1d1d99336ff53fb384fc5c89b6c8 621 PRINTS PR00335 TrkA potassium uptake protein signature 454 464 3.8E-7 T 12-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 VAPA_1c45730 cb0b1d1d99336ff53fb384fc5c89b6c8 621 PRINTS PR00335 TrkA potassium uptake protein signature 465 475 3.8E-7 T 12-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 VAPA_1c45730 cb0b1d1d99336ff53fb384fc5c89b6c8 621 PRINTS PR00335 TrkA potassium uptake protein signature 425 439 3.8E-7 T 12-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 VAPA_1c45730 cb0b1d1d99336ff53fb384fc5c89b6c8 621 PRINTS PR00335 TrkA potassium uptake protein signature 408 422 3.8E-7 T 12-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 VAPA_1c45730 cb0b1d1d99336ff53fb384fc5c89b6c8 621 Pfam PF00999 Sodium/hydrogen exchanger family 13 378 1.1E-63 T 12-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 VAPA_1c45730 cb0b1d1d99336ff53fb384fc5c89b6c8 621 Gene3D G3DSA:1.20.1530.20 6 386 1.5E-79 T 12-10-2018 IPR038770 Sodium/solute symporter superfamily VAPA_1c45730 cb0b1d1d99336ff53fb384fc5c89b6c8 621 SUPERFAMILY SSF51735 408 537 1.03E-32 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c34820 3a2949f7a54db812a80a1aef04fc7ddf 326 Pfam PF16169 Domain of unknown function (DUF4872) 153 321 4.1E-50 T 12-10-2018 IPR032369 Domain of unknown function DUF4872 VAPA_1c34820 3a2949f7a54db812a80a1aef04fc7ddf 326 Pfam PF14399 Butirosin biosynthesis protein H, N-terminal 10 141 3.4E-44 T 12-10-2018 IPR026935 Butirosin biosynthesis protein H, N-terminal KEGG: 00524+2.3.2.19|MetaCyc: PWY-7019 VAPA_1c37040 439b5194d8670039a962d1d17223d9c9 279 Pfam PF04954 Siderophore-interacting protein 151 269 9.8E-37 T 12-10-2018 IPR007037 Siderophore-interacting protein, C-terminal domain VAPA_1c37040 439b5194d8670039a962d1d17223d9c9 279 Gene3D G3DSA:3.40.50.80 145 279 4.0E-42 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain VAPA_1c37040 439b5194d8670039a962d1d17223d9c9 279 Gene3D G3DSA:2.40.30.10 12 144 7.2E-48 T 12-10-2018 VAPA_1c37040 439b5194d8670039a962d1d17223d9c9 279 SUPERFAMILY SSF63380 18 146 7.35E-17 T 12-10-2018 IPR017938 Riboflavin synthase-like beta-barrel VAPA_1c37040 439b5194d8670039a962d1d17223d9c9 279 Pfam PF08021 Siderophore-interacting FAD-binding domain 30 143 3.9E-36 T 12-10-2018 IPR013113 FAD-binding 9, siderophore-interacting VAPA_1c50810 1dd4d0cbb0e8922d0a18cf809b2819f5 414 Pfam PF07690 Major Facilitator Superfamily 20 358 5.2E-29 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 VAPA_1c50810 1dd4d0cbb0e8922d0a18cf809b2819f5 414 SUPERFAMILY SSF103473 9 407 1.7E-50 T 12-10-2018 IPR036259 MFS transporter superfamily VAPA_1c50810 1dd4d0cbb0e8922d0a18cf809b2819f5 414 Gene3D G3DSA:1.20.1250.20 8 402 7.5E-42 T 12-10-2018 VAPA_1c16370 162e16a8ac49cb3e3f9625436f70a52c 950 Gene3D G3DSA:3.30.420.10 351 564 1.6E-63 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 VAPA_1c16370 162e16a8ac49cb3e3f9625436f70a52c 950 SMART SM00279 185 220 1.9E-10 T 12-10-2018 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 VAPA_1c16370 162e16a8ac49cb3e3f9625436f70a52c 950 Gene3D G3DSA:1.20.1060.10 565 680 1.6E-40 T 12-10-2018 VAPA_1c16370 162e16a8ac49cb3e3f9625436f70a52c 950 Gene3D G3DSA:3.30.70.370 686 946 3.1E-109 T 12-10-2018 VAPA_1c16370 162e16a8ac49cb3e3f9625436f70a52c 950 SUPERFAMILY SSF47807 183 304 1.17E-28 T 12-10-2018 IPR036279 5'-3' exonuclease, C-terminal domain superfamily VAPA_1c16370 162e16a8ac49cb3e3f9625436f70a52c 950 Pfam PF00476 DNA polymerase family A 574 947 1.1E-151 T 12-10-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 VAPA_1c16370 162e16a8ac49cb3e3f9625436f70a52c 950 Gene3D G3DSA:1.10.150.20 731 874 3.1E-109 T 12-10-2018 VAPA_1c16370 162e16a8ac49cb3e3f9625436f70a52c 950 Pfam PF02739 5'-3' exonuclease, N-terminal resolvase-like domain 17 181 3.1E-47 T 12-10-2018 IPR020046 5'-3' exonuclease, alpha-helical arch, N-terminal GO:0003677 VAPA_1c16370 162e16a8ac49cb3e3f9625436f70a52c 950 Pfam PF01612 3'-5' exonuclease 354 540 4.9E-35 T 12-10-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 VAPA_1c16370 162e16a8ac49cb3e3f9625436f70a52c 950 Pfam PF01367 5'-3' exonuclease, C-terminal SAM fold 183 268 6.4E-25 T 12-10-2018 IPR020045 DNA polymerase I-like, H3TH domain GO:0003677|GO:0003824 VAPA_1c16370 162e16a8ac49cb3e3f9625436f70a52c 950 SUPERFAMILY SSF56672 545 950 1.05E-153 T 12-10-2018 VAPA_1c16370 162e16a8ac49cb3e3f9625436f70a52c 950 Gene3D G3DSA:1.10.150.20 186 258 6.2E-84 T 12-10-2018 VAPA_1c16370 162e16a8ac49cb3e3f9625436f70a52c 950 SMART SM00475 14 271 7.8E-102 T 12-10-2018 IPR002421 5'-3' exonuclease, N-terminal GO:0003677 VAPA_1c16370 162e16a8ac49cb3e3f9625436f70a52c 950 SMART SM00482 708 914 3.0E-113 T 12-10-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 VAPA_1c16370 162e16a8ac49cb3e3f9625436f70a52c 950 SUPERFAMILY SSF88723 14 182 7.11E-52 T 12-10-2018 IPR029060 PIN-like domain superfamily VAPA_1c16370 162e16a8ac49cb3e3f9625436f70a52c 950 TIGRFAM TIGR00593 pola: DNA polymerase I 17 950 3.9E-263 T 12-10-2018 IPR018320 DNA polymerase 1 GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 VAPA_1c16370 162e16a8ac49cb3e3f9625436f70a52c 950 PRINTS PR00868 DNA-polymerase family A (pol I) signature 835 846 9.4E-78 T 12-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 VAPA_1c16370 162e16a8ac49cb3e3f9625436f70a52c 950 PRINTS PR00868 DNA-polymerase family A (pol I) signature 677 699 9.4E-78 T 12-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 VAPA_1c16370 162e16a8ac49cb3e3f9625436f70a52c 950 PRINTS PR00868 DNA-polymerase family A (pol I) signature 867 883 9.4E-78 T 12-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 VAPA_1c16370 162e16a8ac49cb3e3f9625436f70a52c 950 PRINTS PR00868 DNA-polymerase family A (pol I) signature 722 745 9.4E-78 T 12-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 VAPA_1c16370 162e16a8ac49cb3e3f9625436f70a52c 950 PRINTS PR00868 DNA-polymerase family A (pol I) signature 897 910 9.4E-78 T 12-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 VAPA_1c16370 162e16a8ac49cb3e3f9625436f70a52c 950 PRINTS PR00868 DNA-polymerase family A (pol I) signature 752 765 9.4E-78 T 12-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 VAPA_1c16370 162e16a8ac49cb3e3f9625436f70a52c 950 PRINTS PR00868 DNA-polymerase family A (pol I) signature 700 715 9.4E-78 T 12-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 VAPA_1c16370 162e16a8ac49cb3e3f9625436f70a52c 950 PRINTS PR00868 DNA-polymerase family A (pol I) signature 813 824 9.4E-78 T 12-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 VAPA_1c16370 162e16a8ac49cb3e3f9625436f70a52c 950 PRINTS PR00868 DNA-polymerase family A (pol I) signature 776 801 9.4E-78 T 12-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 VAPA_1c16370 162e16a8ac49cb3e3f9625436f70a52c 950 SUPERFAMILY SSF53098 357 540 2.11E-51 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily VAPA_1c16370 162e16a8ac49cb3e3f9625436f70a52c 950 SMART SM00474 354 540 9.8E-29 T 12-10-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 VAPA_1c16370 162e16a8ac49cb3e3f9625436f70a52c 950 Gene3D G3DSA:3.40.50.1010 17 268 6.2E-84 T 12-10-2018 VAPA_1c16370 162e16a8ac49cb3e3f9625436f70a52c 950 ProSitePatterns PS00447 DNA polymerase family A signature. 776 795 - T 12-10-2018 IPR019760 DNA-directed DNA polymerase, family A, conserved site GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 VAPA_1c49680 52d85d02a6d2946127fea1beb9230c66 697 Gene3D G3DSA:3.40.50.1820 21 653 2.0E-130 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c49680 52d85d02a6d2946127fea1beb9230c66 697 Pfam PF00326 Prolyl oligopeptidase family 490 693 1.0E-45 T 12-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 VAPA_1c49680 52d85d02a6d2946127fea1beb9230c66 697 Gene3D G3DSA:2.130.10.120 71 426 2.0E-130 T 12-10-2018 VAPA_1c49680 52d85d02a6d2946127fea1beb9230c66 697 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 625 647 1.0E-42 T 12-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 VAPA_1c49680 52d85d02a6d2946127fea1beb9230c66 697 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 551 571 1.0E-42 T 12-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 VAPA_1c49680 52d85d02a6d2946127fea1beb9230c66 697 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 466 484 1.0E-42 T 12-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 VAPA_1c49680 52d85d02a6d2946127fea1beb9230c66 697 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 521 540 1.0E-42 T 12-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 VAPA_1c49680 52d85d02a6d2946127fea1beb9230c66 697 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 493 517 1.0E-42 T 12-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 VAPA_1c49680 52d85d02a6d2946127fea1beb9230c66 697 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 606 621 1.0E-42 T 12-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 VAPA_1c49680 52d85d02a6d2946127fea1beb9230c66 697 SUPERFAMILY SSF53474 435 689 7.15E-48 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c49680 52d85d02a6d2946127fea1beb9230c66 697 Pfam PF02897 Prolyl oligopeptidase, N-terminal beta-propeller domain 20 424 6.6E-26 T 12-10-2018 IPR023302 Peptidase S9A, N-terminal domain GO:0004252|GO:0070008 VAPA_1c49680 52d85d02a6d2946127fea1beb9230c66 697 SUPERFAMILY SSF50993 13 431 4.97E-54 T 12-10-2018 VAPA_1c36860 59a531e38d5837b7e4f9426074cca06e 353 Pfam PF00924 Mechanosensitive ion channel 148 323 1.2E-25 T 12-10-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 VAPA_1c36860 59a531e38d5837b7e4f9426074cca06e 353 SUPERFAMILY SSF50182 181 246 2.65E-13 T 12-10-2018 IPR010920 LSM domain superfamily VAPA_2c11460 8cd80544b5e490ac41bfee2c851f5620 723 SMART SM00267 266 439 2.2E-60 T 12-10-2018 IPR000160 GGDEF domain VAPA_2c11460 8cd80544b5e490ac41bfee2c851f5620 723 Gene3D G3DSA:1.20.1480.50 172 270 6.9E-12 T 12-10-2018 VAPA_2c11460 8cd80544b5e490ac41bfee2c851f5620 723 Pfam PF00990 Diguanylate cyclase, GGDEF domain 277 435 2.9E-46 T 12-10-2018 IPR000160 GGDEF domain VAPA_2c11460 8cd80544b5e490ac41bfee2c851f5620 723 Gene3D G3DSA:3.30.70.270 271 451 1.1E-58 T 12-10-2018 VAPA_2c11460 8cd80544b5e490ac41bfee2c851f5620 723 SUPERFAMILY SSF158472 213 261 5.75E-9 T 12-10-2018 VAPA_2c11460 8cd80544b5e490ac41bfee2c851f5620 723 SMART SM00304 212 264 4.0E-10 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 VAPA_2c11460 8cd80544b5e490ac41bfee2c851f5620 723 Gene3D G3DSA:3.20.20.450 452 704 2.4E-107 T 12-10-2018 IPR035919 EAL domain superfamily VAPA_2c11460 8cd80544b5e490ac41bfee2c851f5620 723 Pfam PF00563 EAL domain 457 690 5.0E-78 T 12-10-2018 IPR001633 EAL domain VAPA_2c11460 8cd80544b5e490ac41bfee2c851f5620 723 SUPERFAMILY SSF55073 282 440 1.23E-48 T 12-10-2018 IPR029787 Nucleotide cyclase VAPA_2c11460 8cd80544b5e490ac41bfee2c851f5620 723 SMART SM00052 449 695 1.2E-126 T 12-10-2018 IPR001633 EAL domain VAPA_2c11460 8cd80544b5e490ac41bfee2c851f5620 723 Pfam PF00672 HAMP domain 213 260 1.1E-7 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 VAPA_2c11460 8cd80544b5e490ac41bfee2c851f5620 723 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 273 437 9.1E-42 T 12-10-2018 IPR000160 GGDEF domain VAPA_2c11460 8cd80544b5e490ac41bfee2c851f5620 723 SUPERFAMILY SSF141868 456 702 1.12E-93 T 12-10-2018 IPR035919 EAL domain superfamily VAPA_1c14250 6c30ff6b1801720b3ea2a41bde201856 500 Pfam PF07171 MlrC C-terminus 305 491 7.6E-54 T 12-10-2018 IPR010799 Microcystin LR degradation protein MlrC, C-terminal VAPA_1c14250 6c30ff6b1801720b3ea2a41bde201856 500 PIRSF PIRSF012702 1 500 2.6E-155 T 12-10-2018 IPR009197 Microcystin LR degradation protein MlrC VAPA_1c14250 6c30ff6b1801720b3ea2a41bde201856 500 Pfam PF07364 Metallopeptidase family M81 2 293 3.0E-92 T 12-10-2018 IPR015995 Microcystin LR degradation protein MlrC, N-terminal VAPA_1c05830 d4daa4c2d490e3de3239689743d98d25 715 Pfam PF12770 CHAT domain 444 708 7.4E-65 T 12-10-2018 IPR024983 CHAT domain VAPA_1c05830 d4daa4c2d490e3de3239689743d98d25 715 SUPERFAMILY SSF48452 86 220 6.32E-11 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 VAPA_1c05830 d4daa4c2d490e3de3239689743d98d25 715 Gene3D G3DSA:1.25.40.10 36 369 3.6E-20 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 VAPA_1c46500 c44292549f04a462b66ceece11e30a28 284 SUPERFAMILY SSF53850 86 277 1.12E-19 T 12-10-2018 VAPA_1c46500 c44292549f04a462b66ceece11e30a28 284 Gene3D G3DSA:1.10.10.10 1 84 1.7E-23 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c46500 c44292549f04a462b66ceece11e30a28 284 Gene3D G3DSA:3.40.190.10 85 180 1.3E-12 T 12-10-2018 VAPA_1c46500 c44292549f04a462b66ceece11e30a28 284 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 7.8E-21 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c46500 c44292549f04a462b66ceece11e30a28 284 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 5.4E-9 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c46500 c44292549f04a462b66ceece11e30a28 284 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 5.4E-9 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c46500 c44292549f04a462b66ceece11e30a28 284 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 5.4E-9 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c46500 c44292549f04a462b66ceece11e30a28 284 SUPERFAMILY SSF46785 1 109 7.96E-23 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c46500 c44292549f04a462b66ceece11e30a28 284 Pfam PF03466 LysR substrate binding domain 87 277 1.4E-14 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_1c06470 b6e8a24b0e2f2f61f0c35ad9e10ecb15 161 SUPERFAMILY SSF47240 16 156 4.76E-8 T 12-10-2018 IPR009078 Ferritin-like superfamily VAPA_1c06470 b6e8a24b0e2f2f61f0c35ad9e10ecb15 161 PIRSF PIRSF029477 9 159 1.2E-48 T 12-10-2018 IPR016920 Uncharacterised conserved protein UCP029477 VAPA_1c06470 b6e8a24b0e2f2f61f0c35ad9e10ecb15 161 Pfam PF09537 Domain of unknown function (DUF2383) 15 125 1.1E-37 T 12-10-2018 IPR019052 Domain of unknown function DUF2383 VAPA_1c06470 b6e8a24b0e2f2f61f0c35ad9e10ecb15 161 Gene3D G3DSA:1.20.1260.10 6 156 3.4E-53 T 12-10-2018 IPR012347 Ferritin-like VAPA_1c06470 b6e8a24b0e2f2f61f0c35ad9e10ecb15 161 TIGRFAM TIGR02284 TIGR02284: conserved hypothetical protein 17 153 1.6E-39 T 12-10-2018 IPR011971 Conserved hypothetical protein CHP02284 VAPA_2c07980 a52e812b0859029480e4ea3606a16f17 463 SUPERFAMILY SSF47384 222 304 1.86E-15 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 VAPA_2c07980 a52e812b0859029480e4ea3606a16f17 463 Pfam PF00512 His Kinase A (phospho-acceptor) domain 240 304 9.1E-14 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 VAPA_2c07980 a52e812b0859029480e4ea3606a16f17 463 Gene3D G3DSA:3.30.565.10 309 463 1.3E-35 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_2c07980 a52e812b0859029480e4ea3606a16f17 463 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 352 461 1.3E-19 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase VAPA_2c07980 a52e812b0859029480e4ea3606a16f17 463 SMART SM00387 351 462 9.9E-31 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase VAPA_2c07980 a52e812b0859029480e4ea3606a16f17 463 SMART SM00304 186 238 0.0062 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 VAPA_2c07980 a52e812b0859029480e4ea3606a16f17 463 SMART SM00388 239 304 2.8E-15 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 VAPA_2c07980 a52e812b0859029480e4ea3606a16f17 463 PRINTS PR00344 Bacterial sensor protein C-terminal signature 407 417 6.0E-10 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_2c07980 a52e812b0859029480e4ea3606a16f17 463 PRINTS PR00344 Bacterial sensor protein C-terminal signature 446 459 6.0E-10 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_2c07980 a52e812b0859029480e4ea3606a16f17 463 PRINTS PR00344 Bacterial sensor protein C-terminal signature 421 439 6.0E-10 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_2c07980 a52e812b0859029480e4ea3606a16f17 463 PRINTS PR00344 Bacterial sensor protein C-terminal signature 389 403 6.0E-10 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_2c07980 a52e812b0859029480e4ea3606a16f17 463 Pfam PF08521 Two-component sensor kinase N-terminal 20 162 1.0E-34 T 12-10-2018 IPR013727 Two-component sensor kinase, N-terminal VAPA_2c07980 a52e812b0859029480e4ea3606a16f17 463 Gene3D G3DSA:1.10.287.130 190 303 8.7E-19 T 12-10-2018 VAPA_2c07980 a52e812b0859029480e4ea3606a16f17 463 SUPERFAMILY SSF55874 294 460 3.14E-34 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_1c06660 6f4f26a0353fc086271d8375cd1124f0 299 SUPERFAMILY SSF51735 1 287 1.23E-43 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c06660 6f4f26a0353fc086271d8375cd1124f0 299 Gene3D G3DSA:3.40.50.720 2 297 6.7E-42 T 12-10-2018 VAPA_1c06660 6f4f26a0353fc086271d8375cd1124f0 299 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 212 3.6E-15 T 12-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 VAPA_1c30490 9aee63bddf145bd14153ff24f1ec2218 397 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 66 266 7.3E-20 T 12-10-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain VAPA_1c30490 9aee63bddf145bd14153ff24f1ec2218 397 Gene3D G3DSA:2.40.50.100 64 210 8.6E-69 T 12-10-2018 VAPA_1c30490 9aee63bddf145bd14153ff24f1ec2218 397 Gene3D G3DSA:1.10.287.470 98 170 8.6E-69 T 12-10-2018 VAPA_1c30490 9aee63bddf145bd14153ff24f1ec2218 397 Gene3D G3DSA:2.40.420.20 42 359 8.6E-69 T 12-10-2018 VAPA_1c30490 9aee63bddf145bd14153ff24f1ec2218 397 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 40 361 4.3E-73 T 12-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 VAPA_1c30490 9aee63bddf145bd14153ff24f1ec2218 397 Gene3D G3DSA:2.40.30.170 49 283 8.6E-69 T 12-10-2018 VAPA_1c30490 9aee63bddf145bd14153ff24f1ec2218 397 SUPERFAMILY SSF111369 55 263 9.29E-22 T 12-10-2018 VAPA_1c17570 f3642ab4e88e7d5069ac2277a9406416 477 SUPERFAMILY SSF55103 194 475 6.7E-58 T 12-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 VAPA_1c17570 f3642ab4e88e7d5069ac2277a9406416 477 Gene3D G3DSA:3.30.465.10 99 219 1.2E-46 T 12-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 VAPA_1c17570 f3642ab4e88e7d5069ac2277a9406416 477 Pfam PF02913 FAD linked oxidases, C-terminal domain 221 474 4.3E-54 T 12-10-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 VAPA_1c17570 f3642ab4e88e7d5069ac2277a9406416 477 Gene3D G3DSA:1.10.45.10 435 475 4.2E-16 T 12-10-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 VAPA_1c17570 f3642ab4e88e7d5069ac2277a9406416 477 Gene3D G3DSA:3.30.70.2190 221 346 5.0E-34 T 12-10-2018 VAPA_1c17570 f3642ab4e88e7d5069ac2277a9406416 477 Pfam PF01565 FAD binding domain 45 182 1.1E-35 T 12-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 VAPA_1c17570 f3642ab4e88e7d5069ac2277a9406416 477 Gene3D G3DSA:3.30.43.10 1 97 5.7E-25 T 12-10-2018 IPR016167 FAD-binding, type PCMH, subdomain 1 VAPA_1c17570 f3642ab4e88e7d5069ac2277a9406416 477 SUPERFAMILY SSF56176 8 221 3.02E-75 T 12-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 VAPA_1c17570 f3642ab4e88e7d5069ac2277a9406416 477 Gene3D G3DSA:3.30.70.2740 347 434 5.2E-29 T 12-10-2018 VAPA_2c09210 7b666fb36dd1f078b6412c46c8260e36 152 Gene3D G3DSA:3.30.530.20 4 151 8.9E-32 T 12-10-2018 IPR023393 START-like domain superfamily VAPA_2c09210 7b666fb36dd1f078b6412c46c8260e36 152 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 18 145 2.9E-18 T 12-10-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like VAPA_2c09210 7b666fb36dd1f078b6412c46c8260e36 152 SUPERFAMILY SSF55961 5 150 2.07E-25 T 12-10-2018 VAPA_1c29300 c4310a9b064d86e250f3c0b7caf7ff94 159 SMART SM01103 6 89 5.2E-37 T 12-10-2018 IPR001890 RNA-binding, CRM domain GO:0003723 VAPA_1c29300 c4310a9b064d86e250f3c0b7caf7ff94 159 ProDom PD010559 RNA-BINDING YHBY UPF0044 PREDICTED RNA RIBOSOMAL CONTAINING KH BINDING DOMAIN 15 94 7.0E-33 T 12-10-2018 IPR001890 RNA-binding, CRM domain GO:0003723 VAPA_1c29300 c4310a9b064d86e250f3c0b7caf7ff94 159 SUPERFAMILY SSF75471 5 96 1.57E-26 T 12-10-2018 IPR035920 YhbY-like superfamily VAPA_1c29300 c4310a9b064d86e250f3c0b7caf7ff94 159 Pfam PF01985 CRS1 / YhbY (CRM) domain 6 89 8.5E-16 T 12-10-2018 IPR001890 RNA-binding, CRM domain GO:0003723 VAPA_1c29300 c4310a9b064d86e250f3c0b7caf7ff94 159 Gene3D G3DSA:3.30.110.60 4 103 1.5E-27 T 12-10-2018 IPR035920 YhbY-like superfamily VAPA_1c51510 376d2bd9141766bab7f5865e63701895 290 Pfam PF03466 LysR substrate binding domain 82 285 2.2E-46 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_1c51510 376d2bd9141766bab7f5865e63701895 290 Gene3D G3DSA:1.10.10.10 1 83 6.2E-24 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c51510 376d2bd9141766bab7f5865e63701895 290 Gene3D G3DSA:3.40.190.290 85 284 1.8E-62 T 12-10-2018 VAPA_1c51510 376d2bd9141766bab7f5865e63701895 290 SUPERFAMILY SSF53850 83 288 6.83E-51 T 12-10-2018 VAPA_1c51510 376d2bd9141766bab7f5865e63701895 290 SUPERFAMILY SSF46785 2 106 3.72E-21 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c51510 376d2bd9141766bab7f5865e63701895 290 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 1 57 1.7E-20 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c46070 6666385382968f783b31412acf88ccb0 160 Pfam PF00376 MerR family regulatory protein 17 53 1.5E-14 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 VAPA_1c46070 6666385382968f783b31412acf88ccb0 160 Pfam PF09278 MerR, DNA binding 58 123 2.1E-18 T 12-10-2018 IPR015358 Transcription regulator MerR, DNA binding VAPA_1c46070 6666385382968f783b31412acf88ccb0 160 TIGRFAM TIGR01950 SoxR: redox-sensitive transcriptional activator SoxR 15 154 4.6E-65 T 12-10-2018 IPR010211 Redox-sensitive transcriptional activator SoxR GO:0003677|GO:0006355|GO:0006979|GO:0051537 VAPA_1c46070 6666385382968f783b31412acf88ccb0 160 SUPERFAMILY SSF46955 16 138 1.76E-28 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily VAPA_1c46070 6666385382968f783b31412acf88ccb0 160 Gene3D G3DSA:1.10.1660.10 11 139 1.1E-33 T 12-10-2018 VAPA_1c46070 6666385382968f783b31412acf88ccb0 160 SMART SM00422 16 84 1.8E-24 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 VAPA_1c46070 6666385382968f783b31412acf88ccb0 160 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 17 28 2.5E-13 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 VAPA_1c46070 6666385382968f783b31412acf88ccb0 160 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 28 41 2.5E-13 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 VAPA_1c46070 6666385382968f783b31412acf88ccb0 160 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 51 71 2.5E-13 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 VAPA_1c09770 b42f0972858ca9e65d555f1647255c8e 406 ProSitePatterns PS01135 FtsZ protein signature 2. 97 118 - T 12-10-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 VAPA_1c09770 b42f0972858ca9e65d555f1647255c8e 406 SMART SM00865 207 326 3.9E-48 T 12-10-2018 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-380320 VAPA_1c09770 b42f0972858ca9e65d555f1647255c8e 406 Hamap MF_00909 Cell division protein FtsZ [ftsZ]. 12 335 33.943 T 12-10-2018 IPR000158 Cell division protein FtsZ GO:0005525 VAPA_1c09770 b42f0972858ca9e65d555f1647255c8e 406 PRINTS PR00423 Cell division protein FtsZ signature 98 118 5.5E-44 T 12-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 VAPA_1c09770 b42f0972858ca9e65d555f1647255c8e 406 PRINTS PR00423 Cell division protein FtsZ signature 126 147 5.5E-44 T 12-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 VAPA_1c09770 b42f0972858ca9e65d555f1647255c8e 406 PRINTS PR00423 Cell division protein FtsZ signature 189 211 5.5E-44 T 12-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 VAPA_1c09770 b42f0972858ca9e65d555f1647255c8e 406 PRINTS PR00423 Cell division protein FtsZ signature 212 233 5.5E-44 T 12-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 VAPA_1c09770 b42f0972858ca9e65d555f1647255c8e 406 Gene3D G3DSA:3.40.50.1440 13 318 1.4E-108 T 12-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 VAPA_1c09770 b42f0972858ca9e65d555f1647255c8e 406 Pfam PF12327 FtsZ family, C-terminal domain 222 317 2.5E-27 T 12-10-2018 IPR024757 Cell division protein FtsZ, C-terminal VAPA_1c09770 b42f0972858ca9e65d555f1647255c8e 406 SUPERFAMILY SSF52490 16 208 1.7E-61 T 12-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 VAPA_1c09770 b42f0972858ca9e65d555f1647255c8e 406 TIGRFAM TIGR00065 ftsZ: cell division protein FtsZ 9 324 1.2E-111 T 12-10-2018 IPR000158 Cell division protein FtsZ GO:0005525 VAPA_1c09770 b42f0972858ca9e65d555f1647255c8e 406 SMART SM00864 16 205 4.7E-102 T 12-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 VAPA_1c09770 b42f0972858ca9e65d555f1647255c8e 406 SUPERFAMILY SSF55307 207 321 1.26E-35 T 12-10-2018 IPR008280 Tubulin/FtsZ, C-terminal Reactome: R-HSA-380320 VAPA_1c09770 b42f0972858ca9e65d555f1647255c8e 406 Pfam PF00091 Tubulin/FtsZ family, GTPase domain 16 173 1.2E-36 T 12-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 VAPA_1c38540 06254459e812a4e6609d139a7a866660 217 Pfam PF07077 Protein of unknown function (DUF1345) 35 208 7.1E-62 T 12-10-2018 IPR009781 Protein of unknown function DUF1345 VAPA_1c37130 4dd21d6d0d1791acb091d94f1dccf84e 545 Pfam PF00005 ABC transporter 310 460 3.1E-30 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c37130 4dd21d6d0d1791acb091d94f1dccf84e 545 ProSitePatterns PS00211 ABC transporters family signature. 165 179 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_1c37130 4dd21d6d0d1791acb091d94f1dccf84e 545 Pfam PF00005 ABC transporter 32 192 1.2E-25 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c37130 4dd21d6d0d1791acb091d94f1dccf84e 545 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 244 298 2.1E-5 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 VAPA_1c37130 4dd21d6d0d1791acb091d94f1dccf84e 545 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 512 540 0.0018 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 VAPA_1c37130 4dd21d6d0d1791acb091d94f1dccf84e 545 SUPERFAMILY SSF52540 290 532 1.36E-69 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c37130 4dd21d6d0d1791acb091d94f1dccf84e 545 ProSitePatterns PS00211 ABC transporters family signature. 433 447 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_1c37130 4dd21d6d0d1791acb091d94f1dccf84e 545 SMART SM00382 319 517 5.3E-17 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c37130 4dd21d6d0d1791acb091d94f1dccf84e 545 SMART SM00382 39 242 5.6E-17 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c37130 4dd21d6d0d1791acb091d94f1dccf84e 545 Gene3D G3DSA:3.40.50.300 299 544 2.5E-70 T 12-10-2018 VAPA_1c37130 4dd21d6d0d1791acb091d94f1dccf84e 545 Gene3D G3DSA:3.40.50.300 8 298 2.6E-79 T 12-10-2018 VAPA_1c37130 4dd21d6d0d1791acb091d94f1dccf84e 545 SUPERFAMILY SSF52540 10 263 1.22E-60 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_2c04860 16a5b7f48b2aae79301affdeb62f284f 630 Gene3D G3DSA:1.20.58.760 408 614 1.4E-61 T 12-10-2018 VAPA_2c04860 16a5b7f48b2aae79301affdeb62f284f 630 Gene3D G3DSA:3.40.50.300 141 328 1.3E-64 T 12-10-2018 VAPA_2c04860 16a5b7f48b2aae79301affdeb62f284f 630 TIGRFAM TIGR01241 FtsH_fam: ATP-dependent metallopeptidase HflB 103 601 2.5E-195 T 12-10-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 VAPA_2c04860 16a5b7f48b2aae79301affdeb62f284f 630 SMART SM00382 189 329 1.3E-22 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_2c04860 16a5b7f48b2aae79301affdeb62f284f 630 Hamap MF_01458 ATP-dependent zinc metalloprotease FtsH [ftsH]. 6 617 33.973 T 12-10-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 VAPA_2c04860 16a5b7f48b2aae79301affdeb62f284f 630 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 193 326 5.0E-41 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 VAPA_2c04860 16a5b7f48b2aae79301affdeb62f284f 630 ProSitePatterns PS00674 AAA-protein family signature. 297 315 - T 12-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 VAPA_2c04860 16a5b7f48b2aae79301affdeb62f284f 630 Gene3D G3DSA:1.10.8.60 329 405 2.9E-27 T 12-10-2018 VAPA_2c04860 16a5b7f48b2aae79301affdeb62f284f 630 SUPERFAMILY SSF52540 148 398 3.75E-66 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_2c04860 16a5b7f48b2aae79301affdeb62f284f 630 Pfam PF01434 Peptidase family M41 387 598 1.9E-59 T 12-10-2018 IPR000642 Peptidase M41 GO:0004222|GO:0005524|GO:0006508 Reactome: R-HSA-8949664 VAPA_2c04860 16a5b7f48b2aae79301affdeb62f284f 630 SUPERFAMILY SSF140990 408 603 1.16E-55 T 12-10-2018 IPR037219 Peptidase M41-like GO:0004222|GO:0005524|GO:0006508 Reactome: R-HSA-8949664 VAPA_1c40230 4425634d61ba155f6b80c449d6385ffb 509 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_1c40230 4425634d61ba155f6b80c449d6385ffb 509 Pfam PF00005 ABC transporter 270 425 3.3E-6 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c40230 4425634d61ba155f6b80c449d6385ffb 509 SUPERFAMILY SSF52540 4 223 5.66E-62 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c40230 4425634d61ba155f6b80c449d6385ffb 509 SMART SM00382 30 216 2.2E-8 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c40230 4425634d61ba155f6b80c449d6385ffb 509 Gene3D G3DSA:3.40.50.300 252 485 2.4E-26 T 12-10-2018 VAPA_1c40230 4425634d61ba155f6b80c449d6385ffb 509 Gene3D G3DSA:3.40.50.300 1 233 2.1E-60 T 12-10-2018 VAPA_1c40230 4425634d61ba155f6b80c449d6385ffb 509 SUPERFAMILY SSF52540 253 476 7.62E-30 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c40230 4425634d61ba155f6b80c449d6385ffb 509 Pfam PF00005 ABC transporter 23 166 4.3E-35 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c40230 4425634d61ba155f6b80c449d6385ffb 509 ProSitePatterns PS00211 ABC transporters family signature. 398 412 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_1c38870 557c7c5d39d90c95a8bbc5a039fc81dc 462 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 11 22 - T 12-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 VAPA_1c38870 557c7c5d39d90c95a8bbc5a039fc81dc 462 SUPERFAMILY SSF52374 4 302 6.17E-106 T 12-10-2018 VAPA_1c38870 557c7c5d39d90c95a8bbc5a039fc81dc 462 PRINTS PR00987 Glutamyl-tRNA synthetase signature 22 33 2.0E-25 T 12-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 VAPA_1c38870 557c7c5d39d90c95a8bbc5a039fc81dc 462 PRINTS PR00987 Glutamyl-tRNA synthetase signature 201 209 2.0E-25 T 12-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 VAPA_1c38870 557c7c5d39d90c95a8bbc5a039fc81dc 462 PRINTS PR00987 Glutamyl-tRNA synthetase signature 185 195 2.0E-25 T 12-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 VAPA_1c38870 557c7c5d39d90c95a8bbc5a039fc81dc 462 PRINTS PR00987 Glutamyl-tRNA synthetase signature 37 50 2.0E-25 T 12-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 VAPA_1c38870 557c7c5d39d90c95a8bbc5a039fc81dc 462 PRINTS PR00987 Glutamyl-tRNA synthetase signature 8 20 2.0E-25 T 12-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 VAPA_1c38870 557c7c5d39d90c95a8bbc5a039fc81dc 462 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 4 311 1.2E-100 T 12-10-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0004812|GO:0005524|GO:0043039 VAPA_1c38870 557c7c5d39d90c95a8bbc5a039fc81dc 462 SUPERFAMILY SSF48163 305 462 2.62E-35 T 12-10-2018 IPR008925 Aminoacyl-tRNA synthetase, class I, anticodon-binding GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 VAPA_1c38870 557c7c5d39d90c95a8bbc5a039fc81dc 462 Gene3D G3DSA:3.40.50.620 3 320 9.3E-133 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold VAPA_1c38870 557c7c5d39d90c95a8bbc5a039fc81dc 462 Hamap MF_00022 Glutamate--tRNA ligase [gltX]. 4 462 29.818 T 12-10-2018 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 VAPA_1c38870 557c7c5d39d90c95a8bbc5a039fc81dc 462 Gene3D G3DSA:1.10.10.350 368 462 4.3E-16 T 12-10-2018 IPR020751 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 VAPA_1c38870 557c7c5d39d90c95a8bbc5a039fc81dc 462 TIGRFAM TIGR00464 gltX_bact: glutamate--tRNA ligase 4 460 1.4E-163 T 12-10-2018 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 VAPA_2c12590 4d31b1a23f29fd9118bcd048d566dc6b 385 Gene3D G3DSA:3.30.9.10 85 313 5.9E-94 T 12-10-2018 VAPA_2c12590 4d31b1a23f29fd9118bcd048d566dc6b 385 Pfam PF01266 FAD dependent oxidoreductase 6 350 5.8E-61 T 12-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 VAPA_2c12590 4d31b1a23f29fd9118bcd048d566dc6b 385 Gene3D G3DSA:3.50.50.60 6 356 5.9E-94 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_2c12590 4d31b1a23f29fd9118bcd048d566dc6b 385 SUPERFAMILY SSF51905 5 375 3.76E-58 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c14440 0344cee10767523a69a9576b17062399 2010 Pfam PF01835 MG2 domain 649 768 2.5E-20 T 12-10-2018 IPR002890 Alpha-2-macroglobulin, N-terminal GO:0004866 VAPA_1c14440 0344cee10767523a69a9576b17062399 2010 SMART SM01359 1058 1241 5.3E-48 T 12-10-2018 IPR011625 Alpha-2-macroglobulin, N-terminal 2 VAPA_1c14440 0344cee10767523a69a9576b17062399 2010 Pfam PF11974 Alpha-2-macroglobulin MG1 domain 528 640 2.8E-29 T 12-10-2018 VAPA_1c14440 0344cee10767523a69a9576b17062399 2010 SMART SM01360 1299 1389 8.0E-27 T 12-10-2018 IPR001599 Alpha-2-macroglobulin GO:0004866 VAPA_1c14440 0344cee10767523a69a9576b17062399 2010 Pfam PF00207 Alpha-2-macroglobulin family 1301 1387 7.8E-14 T 12-10-2018 IPR001599 Alpha-2-macroglobulin GO:0004866 VAPA_1c14440 0344cee10767523a69a9576b17062399 2010 Pfam PF07703 Alpha-2-macroglobulin family N-terminal region 1058 1241 6.3E-21 T 12-10-2018 IPR011625 Alpha-2-macroglobulin, N-terminal 2 VAPA_1c11990 d2890b8b78a7eea5a765c5151d81450f 359 SMART SM00842 15 183 0.0044 T 12-10-2018 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0051301 VAPA_1c11990 d2890b8b78a7eea5a765c5151d81450f 359 TIGRFAM TIGR01175 pilM: type IV pilus assembly protein PilM 15 357 1.1E-87 T 12-10-2018 IPR005883 Type IV pilus assembly protein PilM VAPA_1c11990 d2890b8b78a7eea5a765c5151d81450f 359 SUPERFAMILY SSF53067 196 357 1.02E-20 T 12-10-2018 VAPA_1c11990 d2890b8b78a7eea5a765c5151d81450f 359 SUPERFAMILY SSF53067 39 178 7.77E-13 T 12-10-2018 VAPA_1c11990 d2890b8b78a7eea5a765c5151d81450f 359 Gene3D G3DSA:3.30.420.40 194 321 3.7E-80 T 12-10-2018 VAPA_1c11990 d2890b8b78a7eea5a765c5151d81450f 359 PIRSF PIRSF019169 3 358 2.3E-114 T 12-10-2018 IPR005883 Type IV pilus assembly protein PilM VAPA_1c11990 d2890b8b78a7eea5a765c5151d81450f 359 Gene3D G3DSA:3.30.420.40 16 355 3.7E-80 T 12-10-2018 VAPA_1c11990 d2890b8b78a7eea5a765c5151d81450f 359 Pfam PF11104 Type IV pilus assembly protein PilM; 17 357 2.8E-142 T 12-10-2018 IPR005883 Type IV pilus assembly protein PilM VAPA_1c11990 d2890b8b78a7eea5a765c5151d81450f 359 Gene3D G3DSA:3.30.1490.300 92 151 3.7E-80 T 12-10-2018 VAPA_1c54560 b8475516828ea7c9dab460cb299dba54 158 Gene3D G3DSA:2.40.10.330 70 119 1.5E-43 T 12-10-2018 VAPA_1c54560 b8475516828ea7c9dab460cb299dba54 158 SUPERFAMILY SSF54534 2 138 1.91E-24 T 12-10-2018 VAPA_1c54560 b8475516828ea7c9dab460cb299dba54 158 Gene3D G3DSA:3.10.50.40 3 152 1.5E-43 T 12-10-2018 VAPA_1c39040 d3a844e35cec85a2d538a7623ca03859 353 SUPERFAMILY SSF51430 1 349 7.46E-95 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily VAPA_1c39040 d3a844e35cec85a2d538a7623ca03859 353 Pfam PF00248 Aldo/keto reductase family 15 344 7.6E-68 T 12-10-2018 IPR023210 NADP-dependent oxidoreductase domain VAPA_1c39040 d3a844e35cec85a2d538a7623ca03859 353 PRINTS PR00069 Aldo-keto reductase signature 116 134 2.4E-7 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 VAPA_1c39040 d3a844e35cec85a2d538a7623ca03859 353 PRINTS PR00069 Aldo-keto reductase signature 164 181 2.4E-7 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 VAPA_1c39040 d3a844e35cec85a2d538a7623ca03859 353 Gene3D G3DSA:3.20.20.100 1 353 6.7E-112 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily VAPA_1c15080 99115d3edc47008940f4c38f71464a9e 428 Gene3D G3DSA:3.40.50.1100 18 214 6.0E-183 T 12-10-2018 VAPA_1c15080 99115d3edc47008940f4c38f71464a9e 428 ProSitePatterns PS00168 Tryptophan synthase beta chain pyridoxal-phosphate attachment site. 89 103 - T 12-10-2018 IPR006653 Tryptophan synthase, beta chain, conserved site GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 VAPA_1c15080 99115d3edc47008940f4c38f71464a9e 428 Hamap MF_00133 Tryptophan synthase beta chain [trpB]. 10 409 52.15 T 12-10-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 VAPA_1c15080 99115d3edc47008940f4c38f71464a9e 428 TIGRFAM TIGR00263 trpB: tryptophan synthase, beta subunit 15 407 6.9E-187 T 12-10-2018 IPR006654 Tryptophan synthase, beta chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 VAPA_1c15080 99115d3edc47008940f4c38f71464a9e 428 PIRSF PIRSF001413 2 415 2.7E-163 T 12-10-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 VAPA_1c15080 99115d3edc47008940f4c38f71464a9e 428 Gene3D G3DSA:3.40.50.1100 62 402 6.0E-183 T 12-10-2018 VAPA_1c15080 99115d3edc47008940f4c38f71464a9e 428 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 62 396 9.1E-49 T 12-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme VAPA_1c15080 99115d3edc47008940f4c38f71464a9e 428 SUPERFAMILY SSF53686 11 407 4.85E-144 T 12-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme VAPA_2c00290 3a862a8aaf291e612628918c4ae20213 230 Pfam PF00005 ABC transporter 17 158 2.4E-26 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_2c00290 3a862a8aaf291e612628918c4ae20213 230 SMART SM00382 26 215 1.9E-9 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_2c00290 3a862a8aaf291e612628918c4ae20213 230 Gene3D G3DSA:3.40.50.300 1 228 4.0E-56 T 12-10-2018 VAPA_2c00290 3a862a8aaf291e612628918c4ae20213 230 SUPERFAMILY SSF52540 2 222 5.82E-56 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_2c00290 3a862a8aaf291e612628918c4ae20213 230 TIGRFAM TIGR03410 urea_trans_UrtE: urea ABC transporter, ATP-binding protein UrtE 2 229 2.3E-86 T 12-10-2018 IPR017780 ABC transporter, urea, ATP-binding protein, UrtE VAPA_2c01990 3fd7280de68f9676850fe72014fec286 506 Gene3D G3DSA:3.40.309.10 265 463 7.8E-165 T 12-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 VAPA_2c01990 3fd7280de68f9676850fe72014fec286 506 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 261 268 - T 12-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 VAPA_2c01990 3fd7280de68f9676850fe72014fec286 506 Gene3D G3DSA:3.40.605.10 35 491 7.8E-165 T 12-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 VAPA_2c01990 3fd7280de68f9676850fe72014fec286 506 SUPERFAMILY SSF53720 15 498 1.18E-163 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 VAPA_2c01990 3fd7280de68f9676850fe72014fec286 506 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 294 305 - T 12-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 VAPA_2c01990 3fd7280de68f9676850fe72014fec286 506 Pfam PF00171 Aldehyde dehydrogenase family 32 493 7.4E-164 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 VAPA_1c00280 dcc83e9701a8c482b95dcac1d31285a3 316 Gene3D G3DSA:1.10.3680.10 6 114 1.0E-8 T 12-10-2018 IPR029024 TerB-like VAPA_1c00280 dcc83e9701a8c482b95dcac1d31285a3 316 SUPERFAMILY SSF158682 5 113 1.7E-14 T 12-10-2018 IPR029024 TerB-like VAPA_1c00280 dcc83e9701a8c482b95dcac1d31285a3 316 Pfam PF05099 Tellurite resistance protein TerB 7 112 6.5E-8 T 12-10-2018 IPR007791 Co-chaperone DjlA, N-terminal VAPA_1c03650 ace44d6175d67de9746a3dc98a0b2cea 301 Gene3D G3DSA:3.40.190.10 87 180 1.6E-11 T 12-10-2018 VAPA_1c03650 ace44d6175d67de9746a3dc98a0b2cea 301 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 11 66 1.4E-18 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c03650 ace44d6175d67de9746a3dc98a0b2cea 301 Gene3D G3DSA:3.40.190.10 186 270 4.1E-6 T 12-10-2018 VAPA_1c03650 ace44d6175d67de9746a3dc98a0b2cea 301 SUPERFAMILY SSF46785 3 87 7.07E-23 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c03650 ace44d6175d67de9746a3dc98a0b2cea 301 Pfam PF03466 LysR substrate binding domain 92 298 9.0E-24 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_1c03650 ace44d6175d67de9746a3dc98a0b2cea 301 SUPERFAMILY SSF53850 89 296 2.67E-24 T 12-10-2018 VAPA_1c03650 ace44d6175d67de9746a3dc98a0b2cea 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 44 55 8.9E-10 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c03650 ace44d6175d67de9746a3dc98a0b2cea 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 23 34 8.9E-10 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c03650 ace44d6175d67de9746a3dc98a0b2cea 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 44 8.9E-10 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c03650 ace44d6175d67de9746a3dc98a0b2cea 301 Gene3D G3DSA:1.10.10.10 7 86 5.3E-24 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c37150 fd32d7d8ba411bdfecf2da615d3f4ec9 313 Gene3D G3DSA:1.10.3720.10 85 304 5.4E-26 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c37150 fd32d7d8ba411bdfecf2da615d3f4ec9 313 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 114 313 1.8E-38 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 VAPA_1c37150 fd32d7d8ba411bdfecf2da615d3f4ec9 313 SUPERFAMILY SSF161098 94 297 1.96E-19 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c12060 d81d49a37009b9dadfe04ab493f2093d 376 Pfam PF01966 HD domain 63 198 7.7E-15 T 12-10-2018 IPR006674 HD domain VAPA_1c12060 d81d49a37009b9dadfe04ab493f2093d 376 TIGRFAM TIGR01353 dGTP_triPase: putative dGTPase 25 370 7.2E-89 T 12-10-2018 IPR006261 dNTP triphosphohydrolase GO:0016793 VAPA_1c12060 d81d49a37009b9dadfe04ab493f2093d 376 Gene3D G3DSA:1.10.3210.10 1 371 5.2E-131 T 12-10-2018 VAPA_1c12060 d81d49a37009b9dadfe04ab493f2093d 376 SUPERFAMILY SSF109604 14 370 1.93E-88 T 12-10-2018 VAPA_1c12060 d81d49a37009b9dadfe04ab493f2093d 376 SMART SM00471 59 208 3.8E-10 T 12-10-2018 IPR003607 HD/PDEase domain VAPA_1c12060 d81d49a37009b9dadfe04ab493f2093d 376 Pfam PF13286 Phosphohydrolase-associated domain 284 368 3.4E-28 T 12-10-2018 IPR026875 Phosphohydrolase-associated domain VAPA_1c12060 d81d49a37009b9dadfe04ab493f2093d 376 Hamap MF_01212 Deoxyguanosinetriphosphate triphosphohydrolase-like protein. 3 370 36.797 T 12-10-2018 IPR023023 dNTP triphosphohydrolase, type 2 GO:0016793 VAPA_1c09820 cb084b36b2508844d5af8bbd800f7e31 182 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 4 17 1.0E-30 T 12-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 VAPA_1c09820 cb084b36b2508844d5af8bbd800f7e31 182 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 63 79 1.0E-30 T 12-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 VAPA_1c09820 cb084b36b2508844d5af8bbd800f7e31 182 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 85 101 1.0E-30 T 12-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 VAPA_1c09820 cb084b36b2508844d5af8bbd800f7e31 182 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 140 152 1.0E-30 T 12-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 VAPA_1c09820 cb084b36b2508844d5af8bbd800f7e31 182 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 109 128 1.0E-30 T 12-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 VAPA_1c09820 cb084b36b2508844d5af8bbd800f7e31 182 Gene3D G3DSA:3.30.420.10 3 159 2.3E-45 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 VAPA_1c09820 cb084b36b2508844d5af8bbd800f7e31 182 TIGRFAM TIGR00228 ruvC: crossover junction endodeoxyribonuclease RuvC 3 157 8.2E-49 T 12-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 VAPA_1c09820 cb084b36b2508844d5af8bbd800f7e31 182 SUPERFAMILY SSF53098 1 157 3.54E-47 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily VAPA_1c09820 cb084b36b2508844d5af8bbd800f7e31 182 ProSitePatterns PS01321 Crossover junction endodeoxyribonuclease ruvC signature. 115 149 - T 12-10-2018 IPR020563 Crossover junction endodeoxyribonuclease RuvC, magnesium-binding site GO:0008821 VAPA_1c09820 cb084b36b2508844d5af8bbd800f7e31 182 Pfam PF02075 Crossover junction endodeoxyribonuclease RuvC 3 152 4.2E-47 T 12-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 VAPA_1c09820 cb084b36b2508844d5af8bbd800f7e31 182 Hamap MF_00034 Crossover junction endodeoxyribonuclease RuvC [ruvC]. 1 155 41.328 T 12-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 VAPA_1c33410 40cbb7095321ff3fdba0d72be3404a26 320 Gene3D G3DSA:1.10.287.110 2 129 6.9E-31 T 12-10-2018 IPR036869 Chaperone J-domain superfamily VAPA_1c33410 40cbb7095321ff3fdba0d72be3404a26 320 Gene3D G3DSA:2.60.260.20 131 212 3.0E-23 T 12-10-2018 VAPA_1c33410 40cbb7095321ff3fdba0d72be3404a26 320 SUPERFAMILY SSF46565 1 92 2.49E-27 T 12-10-2018 IPR036869 Chaperone J-domain superfamily VAPA_1c33410 40cbb7095321ff3fdba0d72be3404a26 320 PRINTS PR00625 DnaJ domain signature 25 40 4.4E-21 T 12-10-2018 IPR001623 DnaJ domain VAPA_1c33410 40cbb7095321ff3fdba0d72be3404a26 320 PRINTS PR00625 DnaJ domain signature 41 61 4.4E-21 T 12-10-2018 IPR001623 DnaJ domain VAPA_1c33410 40cbb7095321ff3fdba0d72be3404a26 320 PRINTS PR00625 DnaJ domain signature 7 25 4.4E-21 T 12-10-2018 IPR001623 DnaJ domain VAPA_1c33410 40cbb7095321ff3fdba0d72be3404a26 320 PRINTS PR00625 DnaJ domain signature 61 80 4.4E-21 T 12-10-2018 IPR001623 DnaJ domain VAPA_1c33410 40cbb7095321ff3fdba0d72be3404a26 320 Pfam PF01556 DnaJ C terminal domain 138 291 3.1E-29 T 12-10-2018 IPR002939 Chaperone DnaJ, C-terminal VAPA_1c33410 40cbb7095321ff3fdba0d72be3404a26 320 SUPERFAMILY SSF49493 219 301 2.35E-15 T 12-10-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 VAPA_1c33410 40cbb7095321ff3fdba0d72be3404a26 320 SUPERFAMILY SSF49493 129 227 8.76E-20 T 12-10-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 VAPA_1c33410 40cbb7095321ff3fdba0d72be3404a26 320 SMART SM00271 4 61 3.3E-24 T 12-10-2018 IPR001623 DnaJ domain VAPA_1c33410 40cbb7095321ff3fdba0d72be3404a26 320 Gene3D G3DSA:2.60.260.20 214 291 4.3E-21 T 12-10-2018 VAPA_1c33410 40cbb7095321ff3fdba0d72be3404a26 320 Pfam PF00226 DnaJ domain 5 66 5.7E-22 T 12-10-2018 IPR001623 DnaJ domain VAPA_2c12570 3aa1456a05d855a119c9ef0ca1033631 121 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 22 101 1.5E-30 T 12-10-2018 VAPA_2c12570 3aa1456a05d855a119c9ef0ca1033631 121 SUPERFAMILY SSF54292 22 102 4.59E-22 T 12-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 VAPA_2c12570 3aa1456a05d855a119c9ef0ca1033631 121 Gene3D G3DSA:3.10.20.440 9 108 1.2E-21 T 12-10-2018 VAPA_1c39530 c20c8f268feeec209d90e740ee631276 752 SUPERFAMILY SSF56003 10 254 1.05E-42 T 12-10-2018 IPR037165 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain superfamily GO:0016491|GO:0055114 VAPA_1c39530 c20c8f268feeec209d90e740ee631276 752 PIRSF PIRSF036389 2 727 5.3E-239 T 12-10-2018 IPR012368 Oxidoreductase molybdopterin-binding subunit, IorB-related VAPA_1c39530 c20c8f268feeec209d90e740ee631276 752 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 597 674 7.5E-13 T 12-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 VAPA_1c39530 c20c8f268feeec209d90e740ee631276 752 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 16 203 3.4E-17 T 12-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 VAPA_1c39530 c20c8f268feeec209d90e740ee631276 752 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 335 554 1.7E-27 T 12-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 VAPA_1c39530 c20c8f268feeec209d90e740ee631276 752 SUPERFAMILY SSF56003 331 720 8.64E-105 T 12-10-2018 IPR037165 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain superfamily GO:0016491|GO:0055114 VAPA_1c39530 c20c8f268feeec209d90e740ee631276 752 SMART SM01008 220 298 1.4E-19 T 12-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead VAPA_1c39530 c20c8f268feeec209d90e740ee631276 752 Gene3D G3DSA:3.30.365.10 334 552 1.4E-52 T 12-10-2018 VAPA_1c39530 c20c8f268feeec209d90e740ee631276 752 Gene3D G3DSA:3.30.365.10 51 191 4.9E-22 T 12-10-2018 VAPA_1c39530 c20c8f268feeec209d90e740ee631276 752 Gene3D G3DSA:3.30.365.10 579 724 3.8E-35 T 12-10-2018 VAPA_1c39530 c20c8f268feeec209d90e740ee631276 752 Gene3D G3DSA:3.90.1170.50 192 310 8.3E-12 T 12-10-2018 VAPA_1c39530 c20c8f268feeec209d90e740ee631276 752 Gene3D G3DSA:3.30.365.10 346 437 1.4E-52 T 12-10-2018 VAPA_1c13350 db86bbe36f004a028a9aeebc1fcd0ca6 949 SUPERFAMILY SSF50677 207 414 1.88E-45 T 12-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 VAPA_1c13350 db86bbe36f004a028a9aeebc1fcd0ca6 949 SUPERFAMILY SSF52374 9 675 3.33E-129 T 12-10-2018 VAPA_1c13350 db86bbe36f004a028a9aeebc1fcd0ca6 949 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 242 265 2.5E-31 T 12-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 VAPA_1c13350 db86bbe36f004a028a9aeebc1fcd0ca6 949 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 549 562 2.5E-31 T 12-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 VAPA_1c13350 db86bbe36f004a028a9aeebc1fcd0ca6 949 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 588 597 2.5E-31 T 12-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 VAPA_1c13350 db86bbe36f004a028a9aeebc1fcd0ca6 949 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 57 68 2.5E-31 T 12-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 VAPA_1c13350 db86bbe36f004a028a9aeebc1fcd0ca6 949 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 412 427 2.5E-31 T 12-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 VAPA_1c13350 db86bbe36f004a028a9aeebc1fcd0ca6 949 Pfam PF06827 Zinc finger found in FPG and IleRS 910 936 7.4E-8 T 12-10-2018 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 VAPA_1c13350 db86bbe36f004a028a9aeebc1fcd0ca6 949 TIGRFAM TIGR00392 ileS: isoleucine--tRNA ligase 21 866 6.2E-256 T 12-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 VAPA_1c13350 db86bbe36f004a028a9aeebc1fcd0ca6 949 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 64 75 - T 12-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 VAPA_1c13350 db86bbe36f004a028a9aeebc1fcd0ca6 949 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 34 666 8.1E-181 T 12-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 VAPA_1c13350 db86bbe36f004a028a9aeebc1fcd0ca6 949 SUPERFAMILY SSF47323 679 939 1.88E-67 T 12-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 VAPA_1c13350 db86bbe36f004a028a9aeebc1fcd0ca6 949 Gene3D G3DSA:1.10.730.20 668 940 4.9E-86 T 12-10-2018 VAPA_1c13350 db86bbe36f004a028a9aeebc1fcd0ca6 949 Gene3D G3DSA:3.90.740.10 198 419 2.7E-209 T 12-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 VAPA_1c13350 db86bbe36f004a028a9aeebc1fcd0ca6 949 Gene3D G3DSA:3.40.50.620 31 656 2.7E-209 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold VAPA_1c13350 db86bbe36f004a028a9aeebc1fcd0ca6 949 Hamap MF_02002 Isoleucine--tRNA ligase [ileS]. 8 940 19.978 T 12-10-2018 IPR023585 Isoleucine-tRNA ligase, type 1 GO:0004822 KEGG: 00970+6.1.1.5|Reactome: R-HSA-379726 VAPA_1c13350 db86bbe36f004a028a9aeebc1fcd0ca6 949 Pfam PF08264 Anticodon-binding domain of tRNA 712 863 6.6E-23 T 12-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 VAPA_1c48360 4ce3e1e4f63e46790e1d760b41993e03 162 Pfam PF09361 Phasin protein 51 148 4.3E-12 T 12-10-2018 IPR018968 Phasin VAPA_1c48360 4ce3e1e4f63e46790e1d760b41993e03 162 TIGRFAM TIGR01841 phasin: phasin family protein 71 155 1.1E-14 T 12-10-2018 IPR010127 Phasin, subfamily 1 VAPA_2c08800 836fb6f24a51f4dca5e78ad65a18e6a2 347 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 34 87 9.9E-19 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_2c08800 836fb6f24a51f4dca5e78ad65a18e6a2 347 Gene3D G3DSA:1.10.10.10 29 115 1.1E-24 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_2c08800 836fb6f24a51f4dca5e78ad65a18e6a2 347 Gene3D G3DSA:3.40.190.10 117 315 2.0E-62 T 12-10-2018 VAPA_2c08800 836fb6f24a51f4dca5e78ad65a18e6a2 347 Pfam PF03466 LysR substrate binding domain 114 317 5.8E-42 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_2c08800 836fb6f24a51f4dca5e78ad65a18e6a2 347 SUPERFAMILY SSF53850 115 321 1.99E-45 T 12-10-2018 VAPA_2c08800 836fb6f24a51f4dca5e78ad65a18e6a2 347 Gene3D G3DSA:3.40.190.10 189 291 2.0E-62 T 12-10-2018 VAPA_2c08800 836fb6f24a51f4dca5e78ad65a18e6a2 347 SUPERFAMILY SSF46785 32 113 7.83E-20 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_2c08800 836fb6f24a51f4dca5e78ad65a18e6a2 347 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 65 76 4.1E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_2c08800 836fb6f24a51f4dca5e78ad65a18e6a2 347 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 55 65 4.1E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_2c08800 836fb6f24a51f4dca5e78ad65a18e6a2 347 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 44 55 4.1E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c44660 67f558244f368e8c6265466f56cf0b8f 686 Pfam PF05876 Phage terminase large subunit (GpA) 42 623 5.3E-163 T 12-10-2018 IPR008866 Bacteriophage lambda, GpA VAPA_2c02420 d2bba8ca71b7f7e3ac38401b845f62ba 305 SUPERFAMILY SSF49482 3 303 3.92E-86 T 12-10-2018 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 VAPA_2c02420 d2bba8ca71b7f7e3ac38401b845f62ba 305 Gene3D G3DSA:2.60.130.10 2 303 2.8E-116 T 12-10-2018 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 VAPA_2c02420 d2bba8ca71b7f7e3ac38401b845f62ba 305 Pfam PF04444 Catechol dioxygenase N terminus 22 92 3.0E-28 T 12-10-2018 IPR007535 Catechol dioxygenase, N-terminal GO:0005506|GO:0009712|GO:0018576|GO:0055114 VAPA_2c02420 d2bba8ca71b7f7e3ac38401b845f62ba 305 Pfam PF00775 Dioxygenase 118 301 7.5E-47 T 12-10-2018 IPR000627 Intradiol ring-cleavage dioxygenase, C-terminal GO:0003824|GO:0006725|GO:0008199|GO:0055114 VAPA_1c16230 95769a5cd50767ce049d28f8e9af17db 457 Pfam PF00437 Type II/IV secretion system protein 104 380 8.7E-79 T 12-10-2018 IPR001482 Type II/IV secretion system protein VAPA_1c16230 95769a5cd50767ce049d28f8e9af17db 457 SUPERFAMILY SSF52540 84 421 1.8E-62 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c16230 95769a5cd50767ce049d28f8e9af17db 457 Gene3D G3DSA:3.30.450.380 22 198 1.8E-43 T 12-10-2018 VAPA_1c16230 95769a5cd50767ce049d28f8e9af17db 457 Gene3D G3DSA:3.40.50.300 200 422 3.0E-66 T 12-10-2018 VAPA_1c48970 37e90266f6290b798d2b2d6a840204db 712 Pfam PF02092 Glycyl-tRNA synthetase beta subunit 8 574 1.5E-199 T 12-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 VAPA_1c48970 37e90266f6290b798d2b2d6a840204db 712 Pfam PF05746 DALR anticodon binding domain 605 702 1.1E-6 T 12-10-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 VAPA_1c48970 37e90266f6290b798d2b2d6a840204db 712 Hamap MF_00255 Glycine--tRNA ligase beta subunit [glyS]. 5 710 23.065 T 12-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 VAPA_1c48970 37e90266f6290b798d2b2d6a840204db 712 SUPERFAMILY SSF109604 366 511 2.51E-18 T 12-10-2018 VAPA_1c48970 37e90266f6290b798d2b2d6a840204db 712 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 54 66 2.7E-30 T 12-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 VAPA_1c48970 37e90266f6290b798d2b2d6a840204db 712 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 9 22 2.7E-30 T 12-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 VAPA_1c48970 37e90266f6290b798d2b2d6a840204db 712 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 265 280 2.7E-30 T 12-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 VAPA_1c48970 37e90266f6290b798d2b2d6a840204db 712 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 415 434 2.7E-30 T 12-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 VAPA_1c48970 37e90266f6290b798d2b2d6a840204db 712 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 337 353 2.7E-30 T 12-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 VAPA_1c48970 37e90266f6290b798d2b2d6a840204db 712 TIGRFAM TIGR00211 glyS: glycine--tRNA ligase, beta subunit 5 710 2.0E-184 T 12-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 VAPA_1c39420 fe88fca18e2752c93ae974e8dffe3b2d 330 PIRSF PIRSF017082 1 329 2.1E-80 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c39420 fe88fca18e2752c93ae974e8dffe3b2d 330 Gene3D G3DSA:3.40.190.10 132 255 2.0E-115 T 12-10-2018 VAPA_1c39420 fe88fca18e2752c93ae974e8dffe3b2d 330 Gene3D G3DSA:3.40.190.150 35 320 2.0E-115 T 12-10-2018 VAPA_1c39420 fe88fca18e2752c93ae974e8dffe3b2d 330 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 54 325 7.8E-85 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c39420 fe88fca18e2752c93ae974e8dffe3b2d 330 SUPERFAMILY SSF53850 100 290 1.16E-11 T 12-10-2018 VAPA_2c05160 336d5275da39abb438b5e5f0765c7fe4 330 Gene3D G3DSA:3.40.190.10 133 255 2.6E-104 T 12-10-2018 VAPA_2c05160 336d5275da39abb438b5e5f0765c7fe4 330 SUPERFAMILY SSF53850 118 292 7.6E-11 T 12-10-2018 VAPA_2c05160 336d5275da39abb438b5e5f0765c7fe4 330 Gene3D G3DSA:3.40.190.150 36 320 2.6E-104 T 12-10-2018 VAPA_2c05160 336d5275da39abb438b5e5f0765c7fe4 330 PIRSF PIRSF017082 3 329 2.4E-77 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_2c05160 336d5275da39abb438b5e5f0765c7fe4 330 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 56 326 9.9E-77 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_2c04560 0c1f75bed5b6d59057c4acda4c725fb8 441 Gene3D G3DSA:1.20.1250.20 208 427 9.3E-54 T 12-10-2018 VAPA_2c04560 0c1f75bed5b6d59057c4acda4c725fb8 441 Gene3D G3DSA:1.20.1250.20 9 202 1.4E-48 T 12-10-2018 VAPA_2c04560 0c1f75bed5b6d59057c4acda4c725fb8 441 Pfam PF07690 Major Facilitator Superfamily 34 383 3.4E-35 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 VAPA_2c04560 0c1f75bed5b6d59057c4acda4c725fb8 441 SUPERFAMILY SSF103473 8 417 7.06E-62 T 12-10-2018 IPR036259 MFS transporter superfamily VAPA_1c52160 98dd1718da49eeb7e1e3c3a78a6f7d87 143 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 11 131 4.0E-5 T 12-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain VAPA_1c52160 98dd1718da49eeb7e1e3c3a78a6f7d87 143 SUPERFAMILY SSF54593 10 139 3.36E-23 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase VAPA_1c52160 98dd1718da49eeb7e1e3c3a78a6f7d87 143 Gene3D G3DSA:3.10.180.10 6 139 2.3E-35 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase VAPA_1c00450 034c1309526fd9978231d782cb3ccae4 213 Hamap MF_00074 Ribosomal RNA small subunit methyltransferase G [rsmG]. 16 207 25.968 T 12-10-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 VAPA_1c00450 034c1309526fd9978231d782cb3ccae4 213 SUPERFAMILY SSF53335 6 209 3.34E-37 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase VAPA_1c00450 034c1309526fd9978231d782cb3ccae4 213 Gene3D G3DSA:3.40.50.150 2 213 4.1E-66 T 12-10-2018 VAPA_1c00450 034c1309526fd9978231d782cb3ccae4 213 PIRSF PIRSF003078 1 212 1.4E-48 T 12-10-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 VAPA_1c00450 034c1309526fd9978231d782cb3ccae4 213 TIGRFAM TIGR00138 rsmG_gidB: 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG 28 206 1.5E-46 T 12-10-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 VAPA_1c00450 034c1309526fd9978231d782cb3ccae4 213 Pfam PF02527 rRNA small subunit methyltransferase G 23 203 5.3E-48 T 12-10-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 VAPA_2c02610 9fdf1da0610e48b5f2d88701393579e0 540 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 111 440 1.7E-63 T 12-10-2018 IPR000914 Solute-binding protein family 5 domain VAPA_2c02610 9fdf1da0610e48b5f2d88701393579e0 540 Gene3D G3DSA:3.90.76.10 79 219 7.1E-92 T 12-10-2018 VAPA_2c02610 9fdf1da0610e48b5f2d88701393579e0 540 Gene3D G3DSA:3.40.190.10 220 518 7.1E-92 T 12-10-2018 VAPA_2c02610 9fdf1da0610e48b5f2d88701393579e0 540 Gene3D G3DSA:3.10.105.10 298 509 7.1E-92 T 12-10-2018 VAPA_2c02610 9fdf1da0610e48b5f2d88701393579e0 540 PIRSF PIRSF002741 23 539 5.5E-69 T 12-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 VAPA_2c02610 9fdf1da0610e48b5f2d88701393579e0 540 SUPERFAMILY SSF53850 61 531 3.62E-109 T 12-10-2018 VAPA_1c24540 9449c1e2ec54c6c629fe36aa243e6dea 259 ProSitePatterns PS00211 ABC transporters family signature. 156 170 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_1c24540 9449c1e2ec54c6c629fe36aa243e6dea 259 Pfam PF00005 ABC transporter 28 183 4.1E-33 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c24540 9449c1e2ec54c6c629fe36aa243e6dea 259 TIGRFAM TIGR00972 3a0107s01c2: phosphate ABC transporter, ATP-binding protein 13 259 2.2E-119 T 12-10-2018 IPR005670 Phosphate transport system permease protein 1 GO:0005315|GO:0016020|GO:0035435 VAPA_1c24540 9449c1e2ec54c6c629fe36aa243e6dea 259 SUPERFAMILY SSF52540 13 245 5.56E-60 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c24540 9449c1e2ec54c6c629fe36aa243e6dea 259 Gene3D G3DSA:3.40.50.300 11 257 6.1E-66 T 12-10-2018 VAPA_1c24540 9449c1e2ec54c6c629fe36aa243e6dea 259 SMART SM00382 37 247 1.2E-10 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c45100 342e548c0a5d083be76181ca11b17fb5 270 Pfam PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain 1 112 5.8E-27 T 12-10-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 VAPA_1c45100 342e548c0a5d083be76181ca11b17fb5 270 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 130 219 5.0E-23 T 12-10-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 VAPA_1c45100 342e548c0a5d083be76181ca11b17fb5 270 SMART SM00898 2 113 8.5E-40 T 12-10-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 VAPA_1c45100 342e548c0a5d083be76181ca11b17fb5 270 SUPERFAMILY SSF81624 2 139 3.53E-30 T 12-10-2018 IPR035937 MutM-like, N-terminal VAPA_1c45100 342e548c0a5d083be76181ca11b17fb5 270 Gene3D G3DSA:1.10.8.50 132 270 4.0E-45 T 12-10-2018 VAPA_1c45100 342e548c0a5d083be76181ca11b17fb5 270 SUPERFAMILY SSF57716 218 270 2.68E-18 T 12-10-2018 VAPA_1c45100 342e548c0a5d083be76181ca11b17fb5 270 SMART SM01232 130 222 5.7E-42 T 12-10-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 VAPA_1c45100 342e548c0a5d083be76181ca11b17fb5 270 Gene3D G3DSA:3.20.190.10 2 124 2.8E-29 T 12-10-2018 IPR035937 MutM-like, N-terminal VAPA_1c45100 342e548c0a5d083be76181ca11b17fb5 270 Hamap MF_00103 Formamidopyrimidine-DNA glycosylase [mutM]. 1 270 40.673 T 12-10-2018 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 VAPA_1c45100 342e548c0a5d083be76181ca11b17fb5 270 SUPERFAMILY SSF46946 131 223 2.21E-26 T 12-10-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 VAPA_1c45100 342e548c0a5d083be76181ca11b17fb5 270 ProSitePatterns PS01242 Zinc finger FPG-type signature. 245 269 - T 12-10-2018 IPR015887 DNA glycosylase/AP lyase, zinc finger domain, DNA-binding site GO:0003677|GO:0003906|GO:0006281|GO:0008270|GO:0016799 VAPA_1c45100 342e548c0a5d083be76181ca11b17fb5 270 TIGRFAM TIGR00577 fpg: DNA-formamidopyrimidine glycosylase 1 269 9.7E-82 T 12-10-2018 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 VAPA_1c45100 342e548c0a5d083be76181ca11b17fb5 270 Pfam PF06827 Zinc finger found in FPG and IleRS 242 270 1.2E-10 T 12-10-2018 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 VAPA_1c02420 ea5474b696009ac0fe905215f8b7fba2 272 SMART SM00332 4 251 7.8E-10 T 12-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 VAPA_1c02420 ea5474b696009ac0fe905215f8b7fba2 272 Gene3D G3DSA:3.60.40.10 3 253 1.6E-46 T 12-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 VAPA_1c02420 ea5474b696009ac0fe905215f8b7fba2 272 SUPERFAMILY SSF81606 13 253 2.22E-43 T 12-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 VAPA_1c02420 ea5474b696009ac0fe905215f8b7fba2 272 SMART SM00331 18 253 1.0E-5 T 12-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 VAPA_1c02420 ea5474b696009ac0fe905215f8b7fba2 272 Pfam PF13672 Protein phosphatase 2C 20 216 4.3E-19 T 12-10-2018 VAPA_2c11610 b91c105a8457cb69c36fb0747c7c69fc 288 SMART SM00382 30 255 6.3E-9 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_2c11610 b91c105a8457cb69c36fb0747c7c69fc 288 Pfam PF00005 ABC transporter 21 182 4.1E-28 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_2c11610 b91c105a8457cb69c36fb0747c7c69fc 288 TIGRFAM TIGR02315 ABC_phnC: phosphonate ABC transporter, ATP-binding protein 4 251 5.9E-93 T 12-10-2018 IPR012693 ABC transporter, phosphonate import, PhnC GO:0005524|GO:0015416|GO:0015716|GO:0016020 VAPA_2c11610 b91c105a8457cb69c36fb0747c7c69fc 288 Gene3D G3DSA:3.40.50.300 4 263 5.2E-61 T 12-10-2018 VAPA_2c11610 b91c105a8457cb69c36fb0747c7c69fc 288 ProSitePatterns PS00211 ABC transporters family signature. 154 168 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_2c11610 b91c105a8457cb69c36fb0747c7c69fc 288 SUPERFAMILY SSF52540 4 241 6.83E-57 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c31130 17b322c7e9c6bd0ac18d148bc09e0cf9 339 Gene3D G3DSA:3.40.50.300 6 209 2.8E-35 T 12-10-2018 VAPA_1c31130 17b322c7e9c6bd0ac18d148bc09e0cf9 339 SMART SM00382 41 185 0.002 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c31130 17b322c7e9c6bd0ac18d148bc09e0cf9 339 SUPERFAMILY SSF52540 7 310 2.25E-30 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c31130 17b322c7e9c6bd0ac18d148bc09e0cf9 339 PIRSF PIRSF002849 1 339 8.5E-79 T 12-10-2018 VAPA_1c31130 17b322c7e9c6bd0ac18d148bc09e0cf9 339 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 44 177 3.5E-26 T 12-10-2018 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 VAPA_1c31130 17b322c7e9c6bd0ac18d148bc09e0cf9 339 Gene3D G3DSA:1.10.8.300 214 336 1.2E-23 T 12-10-2018 VAPA_1c26480 2fbe7714bd083ad81e8bdcee21a38267 414 SUPERFAMILY SSF53383 10 385 4.19E-95 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase VAPA_1c26480 2fbe7714bd083ad81e8bdcee21a38267 414 Gene3D G3DSA:3.40.640.10 23 280 2.5E-115 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 VAPA_1c26480 2fbe7714bd083ad81e8bdcee21a38267 414 Gene3D G3DSA:3.90.1150.10 18 393 2.5E-115 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 VAPA_1c26480 2fbe7714bd083ad81e8bdcee21a38267 414 Pfam PF00266 Aminotransferase class-V 13 348 7.7E-26 T 12-10-2018 IPR000192 Aminotransferase class V domain VAPA_1c26480 2fbe7714bd083ad81e8bdcee21a38267 414 PIRSF PIRSF000524 6 406 7.6E-120 T 12-10-2018 IPR024169 Serine-pyruvate aminotransferase/2-aminoethylphosphonate-pyruvate transaminase KEGG: 00440+2.6.1.37|MetaCyc: PWY-6832|Reactome: R-HSA-389661|Reactome: R-HSA-9033241 VAPA_1c18520 b1fadf70dce52e0fe48fd48108a8a0b5 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 75 86 4.6E-8 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c18520 b1fadf70dce52e0fe48fd48108a8a0b5 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 138 146 4.6E-8 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c18520 b1fadf70dce52e0fe48fd48108a8a0b5 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 158 177 4.6E-8 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c18520 b1fadf70dce52e0fe48fd48108a8a0b5 252 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 145 173 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 VAPA_1c18520 b1fadf70dce52e0fe48fd48108a8a0b5 252 Gene3D G3DSA:3.40.50.720 1 250 3.8E-72 T 12-10-2018 VAPA_1c18520 b1fadf70dce52e0fe48fd48108a8a0b5 252 SUPERFAMILY SSF51735 3 246 1.17E-55 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c18520 b1fadf70dce52e0fe48fd48108a8a0b5 252 Pfam PF00106 short chain dehydrogenase 6 196 4.1E-40 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c18520 b1fadf70dce52e0fe48fd48108a8a0b5 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 213 233 1.4E-24 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c18520 b1fadf70dce52e0fe48fd48108a8a0b5 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 1.4E-24 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c18520 b1fadf70dce52e0fe48fd48108a8a0b5 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 1.4E-24 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c18520 b1fadf70dce52e0fe48fd48108a8a0b5 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 75 86 1.4E-24 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c18520 b1fadf70dce52e0fe48fd48108a8a0b5 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 1.4E-24 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c18520 b1fadf70dce52e0fe48fd48108a8a0b5 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 1.4E-24 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c22480 0b328e0fe1266479426df00244dce528 245 SMART SM00382 26 213 5.9E-16 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c22480 0b328e0fe1266479426df00244dce528 245 Pfam PF00005 ABC transporter 17 165 2.3E-34 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c22480 0b328e0fe1266479426df00244dce528 245 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_1c22480 0b328e0fe1266479426df00244dce528 245 PIRSF PIRSF039085 1 244 4.4E-98 T 12-10-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 VAPA_1c22480 0b328e0fe1266479426df00244dce528 245 SUPERFAMILY SSF52540 1 232 1.01E-71 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c22480 0b328e0fe1266479426df00244dce528 245 Gene3D G3DSA:3.40.50.300 1 243 7.6E-70 T 12-10-2018 VAPA_1c47720 23e026c00c773744daea4a660cfa8b96 307 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 27 38 6.0E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c47720 23e026c00c773744daea4a660cfa8b96 307 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 38 48 6.0E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c47720 23e026c00c773744daea4a660cfa8b96 307 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 48 59 6.0E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c47720 23e026c00c773744daea4a660cfa8b96 307 Gene3D G3DSA:3.40.190.10 101 292 1.2E-47 T 12-10-2018 VAPA_1c47720 23e026c00c773744daea4a660cfa8b96 307 Gene3D G3DSA:3.40.190.10 175 275 1.2E-47 T 12-10-2018 VAPA_1c47720 23e026c00c773744daea4a660cfa8b96 307 SUPERFAMILY SSF53850 98 305 5.65E-27 T 12-10-2018 VAPA_1c47720 23e026c00c773744daea4a660cfa8b96 307 SUPERFAMILY SSF46785 9 119 4.08E-20 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c47720 23e026c00c773744daea4a660cfa8b96 307 Pfam PF03466 LysR substrate binding domain 96 303 7.7E-24 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_1c47720 23e026c00c773744daea4a660cfa8b96 307 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 14 71 2.4E-16 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c47720 23e026c00c773744daea4a660cfa8b96 307 Gene3D G3DSA:1.10.10.10 10 98 2.5E-20 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c11740 a33bc18bbe2765c70257b13035302d08 550 TIGRFAM TIGR02348 GroEL: chaperonin GroL 3 527 2.6E-252 T 12-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 VAPA_1c11740 a33bc18bbe2765c70257b13035302d08 550 Gene3D G3DSA:3.50.7.10 192 372 3.8E-233 T 12-10-2018 IPR027409 GroEL-like apical domain superfamily VAPA_1c11740 a33bc18bbe2765c70257b13035302d08 550 SUPERFAMILY SSF48592 7 522 3.36E-76 T 12-10-2018 IPR027413 GroEL-like equatorial domain superfamily VAPA_1c11740 a33bc18bbe2765c70257b13035302d08 550 Gene3D G3DSA:1.10.560.10 8 522 3.8E-233 T 12-10-2018 IPR027413 GroEL-like equatorial domain superfamily VAPA_1c11740 a33bc18bbe2765c70257b13035302d08 550 SUPERFAMILY SSF52029 185 376 7.63E-82 T 12-10-2018 IPR027409 GroEL-like apical domain superfamily VAPA_1c11740 a33bc18bbe2765c70257b13035302d08 550 Hamap MF_00600 60 kDa chaperonin [groL]. 2 548 41.629 T 12-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 VAPA_1c11740 a33bc18bbe2765c70257b13035302d08 550 PRINTS PR00298 60kDa chaperonin signature 83 110 4.9E-74 T 12-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 VAPA_1c11740 a33bc18bbe2765c70257b13035302d08 550 PRINTS PR00298 60kDa chaperonin signature 350 375 4.9E-74 T 12-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 VAPA_1c11740 a33bc18bbe2765c70257b13035302d08 550 PRINTS PR00298 60kDa chaperonin signature 268 291 4.9E-74 T 12-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 VAPA_1c11740 a33bc18bbe2765c70257b13035302d08 550 PRINTS PR00298 60kDa chaperonin signature 398 419 4.9E-74 T 12-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 VAPA_1c11740 a33bc18bbe2765c70257b13035302d08 550 PRINTS PR00298 60kDa chaperonin signature 27 53 4.9E-74 T 12-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 VAPA_1c11740 a33bc18bbe2765c70257b13035302d08 550 Gene3D G3DSA:3.30.260.10 136 410 3.8E-233 T 12-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily VAPA_1c11740 a33bc18bbe2765c70257b13035302d08 550 ProSitePatterns PS00296 Chaperonins cpn60 signature. 405 416 - T 12-10-2018 IPR018370 Chaperonin Cpn60, conserved site GO:0005524|GO:0005737|GO:0006457 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 VAPA_1c11740 a33bc18bbe2765c70257b13035302d08 550 SUPERFAMILY SSF54849 137 203 1.19E-24 T 12-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily VAPA_1c11740 a33bc18bbe2765c70257b13035302d08 550 Pfam PF00118 TCP-1/cpn60 chaperonin family 23 525 2.2E-98 T 12-10-2018 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 VAPA_1c15290 388026de4b64d9fc8515fdd7993480f5 862 Gene3D G3DSA:3.30.499.10 684 861 5.5E-63 T 12-10-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 KEGG: 00290+4.2.1.33 VAPA_1c15290 388026de4b64d9fc8515fdd7993480f5 862 Pfam PF00330 Aconitase family (aconitate hydratase) 460 815 2.8E-39 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 VAPA_1c15290 388026de4b64d9fc8515fdd7993480f5 862 TIGRFAM TIGR00117 acnB: aconitate hydratase 2 1 853 0.0 T 12-10-2018 IPR004406 Aconitase B GO:0003994|GO:0005829|GO:0006099|GO:0051539 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00640+4.2.1.99|KEGG: 00720+4.2.1.3|MetaCyc: PWY-5747 VAPA_1c15290 388026de4b64d9fc8515fdd7993480f5 862 ProSitePatterns PS01244 Aconitase family signature 2. 761 774 - T 12-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 VAPA_1c15290 388026de4b64d9fc8515fdd7993480f5 862 SUPERFAMILY SSF74778 1 160 3.53E-62 T 12-10-2018 IPR036288 Aconitase B, HEAT-like domain superfamily GO:0003994|GO:0006099 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00640+4.2.1.99|KEGG: 00720+4.2.1.3|MetaCyc: PWY-5747 VAPA_1c15290 388026de4b64d9fc8515fdd7993480f5 862 Pfam PF06434 Aconitate hydratase 2 N-terminus 168 380 5.1E-93 T 12-10-2018 IPR015929 Aconitase B, swivel GO:0003994|GO:0006099 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00640+4.2.1.99|KEGG: 00720+4.2.1.3|MetaCyc: PWY-5747 VAPA_1c15290 388026de4b64d9fc8515fdd7993480f5 862 Gene3D G3DSA:3.40.1060.10 383 682 1.6E-149 T 12-10-2018 IPR015932 Aconitase, domain 2 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00720+4.2.1.3|Reactome: R-HSA-1268020|Reactome: R-HSA-71403 VAPA_1c15290 388026de4b64d9fc8515fdd7993480f5 862 ProSitePatterns PS00450 Aconitase family signature 1. 703 720 - T 12-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 VAPA_1c15290 388026de4b64d9fc8515fdd7993480f5 862 Gene3D G3DSA:1.25.40.310 1 161 1.0E-63 T 12-10-2018 IPR036288 Aconitase B, HEAT-like domain superfamily GO:0003994|GO:0006099 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00640+4.2.1.99|KEGG: 00720+4.2.1.3|MetaCyc: PWY-5747 VAPA_1c15290 388026de4b64d9fc8515fdd7993480f5 862 Gene3D G3DSA:3.30.499.10 403 530 1.6E-149 T 12-10-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 KEGG: 00290+4.2.1.33 VAPA_1c15290 388026de4b64d9fc8515fdd7993480f5 862 Pfam PF11791 Aconitate B N-terminal domain 4 156 3.4E-60 T 12-10-2018 IPR015933 Aconitase B, HEAT-like domain GO:0003994|GO:0006099 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00640+4.2.1.99|KEGG: 00720+4.2.1.3|MetaCyc: PWY-5747 VAPA_1c15290 388026de4b64d9fc8515fdd7993480f5 862 SUPERFAMILY SSF53732 378 856 3.53E-144 T 12-10-2018 IPR036008 Aconitase, iron-sulfur domain KEGG: 00290+4.2.1.33 VAPA_1c15290 388026de4b64d9fc8515fdd7993480f5 862 SUPERFAMILY SSF52016 162 370 5.1E-66 T 12-10-2018 VAPA_1c15290 388026de4b64d9fc8515fdd7993480f5 862 Gene3D G3DSA:3.20.19.10 162 359 6.0E-70 T 12-10-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel KEGG: 00290+4.2.1.33 VAPA_1c15290 388026de4b64d9fc8515fdd7993480f5 862 PIRSF PIRSF036687 1 859 0.0 T 12-10-2018 IPR004406 Aconitase B GO:0003994|GO:0005829|GO:0006099|GO:0051539 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00640+4.2.1.99|KEGG: 00720+4.2.1.3|MetaCyc: PWY-5747 VAPA_2c09330 327ab33b9f923b5629cac4ef3d816929 204 Gene3D G3DSA:3.40.30.10 2 197 2.4E-61 T 12-10-2018 VAPA_2c09330 327ab33b9f923b5629cac4ef3d816929 204 Gene3D G3DSA:1.20.1050.10 83 188 2.4E-61 T 12-10-2018 VAPA_2c09330 327ab33b9f923b5629cac4ef3d816929 204 Pfam PF13417 Glutathione S-transferase, N-terminal domain 15 77 1.4E-7 T 12-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 VAPA_2c09330 327ab33b9f923b5629cac4ef3d816929 204 SUPERFAMILY SSF47616 80 198 8.49E-24 T 12-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily VAPA_2c09330 327ab33b9f923b5629cac4ef3d816929 204 SUPERFAMILY SSF52833 1 83 4.21E-18 T 12-10-2018 IPR036249 Thioredoxin-like superfamily VAPA_2c09330 327ab33b9f923b5629cac4ef3d816929 204 Pfam PF00043 Glutathione S-transferase, C-terminal domain 106 188 1.8E-10 T 12-10-2018 IPR004046 Glutathione S-transferase, C-terminal VAPA_1c19060 87f3482190f71540ce781c3b4d8ba0f3 150 Gene3D G3DSA:3.10.430.100 61 148 3.1E-25 T 12-10-2018 IPR036791 Ribosomal protein L9, C-terminal domain superfamily VAPA_1c19060 87f3482190f71540ce781c3b4d8ba0f3 150 SUPERFAMILY SSF55658 1 56 1.92E-16 T 12-10-2018 IPR009027 Ribosomal protein L9/RNase H1, N-terminal VAPA_1c19060 87f3482190f71540ce781c3b4d8ba0f3 150 ProSitePatterns PS00651 Ribosomal protein L9 signature. 13 40 - T 12-10-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 VAPA_1c19060 87f3482190f71540ce781c3b4d8ba0f3 150 Hamap MF_00503 50S ribosomal protein L9 [rplI]. 1 148 24.294 T 12-10-2018 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 VAPA_1c19060 87f3482190f71540ce781c3b4d8ba0f3 150 Pfam PF01281 Ribosomal protein L9, N-terminal domain 1 47 9.5E-20 T 12-10-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 VAPA_1c19060 87f3482190f71540ce781c3b4d8ba0f3 150 SUPERFAMILY SSF55653 60 147 6.93E-25 T 12-10-2018 IPR036791 Ribosomal protein L9, C-terminal domain superfamily VAPA_1c19060 87f3482190f71540ce781c3b4d8ba0f3 150 Gene3D G3DSA:3.40.5.10 1 50 7.6E-20 T 12-10-2018 IPR036935 Ribosomal protein L9, N-terminal domain superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 VAPA_1c19060 87f3482190f71540ce781c3b4d8ba0f3 150 Pfam PF03948 Ribosomal protein L9, C-terminal domain 64 145 7.2E-25 T 12-10-2018 IPR020069 Ribosomal protein L9, C-terminal VAPA_1c19060 87f3482190f71540ce781c3b4d8ba0f3 150 TIGRFAM TIGR00158 L9: ribosomal protein bL9 1 146 5.8E-40 T 12-10-2018 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 VAPA_1c25260 f21c9a0022c0aac03128ffc4f533f725 491 Gene3D G3DSA:2.30.42.10 289 397 8.6E-26 T 12-10-2018 VAPA_1c25260 f21c9a0022c0aac03128ffc4f533f725 491 SUPERFAMILY SSF50156 252 377 6.44E-24 T 12-10-2018 IPR036034 PDZ superfamily GO:0005515 VAPA_1c25260 f21c9a0022c0aac03128ffc4f533f725 491 SMART SM00228 294 376 1.4E-12 T 12-10-2018 IPR001478 PDZ domain GO:0005515 VAPA_1c25260 f21c9a0022c0aac03128ffc4f533f725 491 SMART SM00228 405 481 5.4E-8 T 12-10-2018 IPR001478 PDZ domain GO:0005515 VAPA_1c25260 f21c9a0022c0aac03128ffc4f533f725 491 SUPERFAMILY SSF50494 53 285 1.99E-63 T 12-10-2018 IPR009003 Peptidase S1, PA clan VAPA_1c25260 f21c9a0022c0aac03128ffc4f533f725 491 Pfam PF13180 PDZ domain 295 384 3.0E-15 T 12-10-2018 IPR001478 PDZ domain GO:0005515 VAPA_1c25260 f21c9a0022c0aac03128ffc4f533f725 491 Gene3D G3DSA:2.30.42.10 410 490 9.7E-15 T 12-10-2018 VAPA_1c25260 f21c9a0022c0aac03128ffc4f533f725 491 Pfam PF00595 PDZ domain (Also known as DHR or GLGF) 402 478 1.1E-6 T 12-10-2018 IPR001478 PDZ domain GO:0005515 VAPA_1c25260 f21c9a0022c0aac03128ffc4f533f725 491 TIGRFAM TIGR02037 degP_htrA_DO: peptidase Do 55 486 4.6E-146 T 12-10-2018 IPR011782 Peptidase S1C, Do GO:0004252|GO:0006508 VAPA_1c25260 f21c9a0022c0aac03128ffc4f533f725 491 SUPERFAMILY SSF50156 405 490 2.89E-13 T 12-10-2018 IPR036034 PDZ superfamily GO:0005515 VAPA_1c25260 f21c9a0022c0aac03128ffc4f533f725 491 Pfam PF13365 Trypsin-like peptidase domain 122 255 3.9E-35 T 12-10-2018 VAPA_1c25260 f21c9a0022c0aac03128ffc4f533f725 491 Gene3D G3DSA:2.40.10.120 53 287 3.6E-81 T 12-10-2018 VAPA_1c25260 f21c9a0022c0aac03128ffc4f533f725 491 PRINTS PR00834 HtrA/DegQ protease family signature 131 143 2.4E-50 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 VAPA_1c25260 f21c9a0022c0aac03128ffc4f533f725 491 PRINTS PR00834 HtrA/DegQ protease family signature 192 216 2.4E-50 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 VAPA_1c25260 f21c9a0022c0aac03128ffc4f533f725 491 PRINTS PR00834 HtrA/DegQ protease family signature 248 265 2.4E-50 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 VAPA_1c25260 f21c9a0022c0aac03128ffc4f533f725 491 PRINTS PR00834 HtrA/DegQ protease family signature 334 346 2.4E-50 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 VAPA_1c25260 f21c9a0022c0aac03128ffc4f533f725 491 PRINTS PR00834 HtrA/DegQ protease family signature 152 172 2.4E-50 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 VAPA_1c25260 f21c9a0022c0aac03128ffc4f533f725 491 PRINTS PR00834 HtrA/DegQ protease family signature 226 243 2.4E-50 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 VAPA_1c31780 848ed995f7fe87565f1e9a51bf665a27 384 SUPERFAMILY SSF142695 221 381 1.09E-37 T 12-10-2018 IPR036144 RibA-like superfamily KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 VAPA_1c31780 848ed995f7fe87565f1e9a51bf665a27 384 SUPERFAMILY SSF55821 18 219 2.98E-84 T 12-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily VAPA_1c31780 848ed995f7fe87565f1e9a51bf665a27 384 Hamap MF_00180 3,4-dihydroxy-2-butanone 4-phosphate synthase [ribB]. 18 220 37.893 T 12-10-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 VAPA_1c31780 848ed995f7fe87565f1e9a51bf665a27 384 TIGRFAM TIGR00506 ribB: 3,4-dihydroxy-2-butanone-4-phosphate synthase 21 216 1.6E-72 T 12-10-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 VAPA_1c31780 848ed995f7fe87565f1e9a51bf665a27 384 Gene3D G3DSA:3.90.870.10 11 222 6.0E-84 T 12-10-2018 VAPA_1c31780 848ed995f7fe87565f1e9a51bf665a27 384 Pfam PF00926 3,4-dihydroxy-2-butanone 4-phosphate synthase 24 214 5.7E-80 T 12-10-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 VAPA_1c31780 848ed995f7fe87565f1e9a51bf665a27 384 Pfam PF00925 GTP cyclohydrolase II 229 380 1.1E-30 T 12-10-2018 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 VAPA_1c31780 848ed995f7fe87565f1e9a51bf665a27 384 PIRSF PIRSF001259 19 383 3.4E-110 T 12-10-2018 VAPA_1c16510 a0ca2ca6b97ccb4f8045ace33d416d6e 525 Gene3D G3DSA:3.10.105.10 274 500 7.1E-91 T 12-10-2018 VAPA_1c16510 a0ca2ca6b97ccb4f8045ace33d416d6e 525 PIRSF PIRSF002741 2 524 4.0E-63 T 12-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 VAPA_1c16510 a0ca2ca6b97ccb4f8045ace33d416d6e 525 Gene3D G3DSA:3.40.190.10 187 509 7.1E-91 T 12-10-2018 VAPA_1c16510 a0ca2ca6b97ccb4f8045ace33d416d6e 525 SUPERFAMILY SSF53850 26 519 1.12E-103 T 12-10-2018 VAPA_1c16510 a0ca2ca6b97ccb4f8045ace33d416d6e 525 Gene3D G3DSA:3.90.76.10 37 186 7.1E-91 T 12-10-2018 VAPA_1c16510 a0ca2ca6b97ccb4f8045ace33d416d6e 525 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 70 430 3.1E-76 T 12-10-2018 IPR000914 Solute-binding protein family 5 domain VAPA_1c30530 2cadc8c86de9888432cb19e5d47f0b15 419 Gene3D G3DSA:3.90.660.10 38 377 5.2E-20 T 12-10-2018 VAPA_1c30530 2cadc8c86de9888432cb19e5d47f0b15 419 Gene3D G3DSA:3.50.50.60 4 414 5.2E-20 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c30530 2cadc8c86de9888432cb19e5d47f0b15 419 SUPERFAMILY SSF51905 2 414 2.59E-41 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c30530 2cadc8c86de9888432cb19e5d47f0b15 419 Pfam PF01593 Flavin containing amine oxidoreductase 11 414 5.6E-21 T 12-10-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 VAPA_1c30530 2cadc8c86de9888432cb19e5d47f0b15 419 TIGRFAM TIGR03467 HpnE: squalene-associated FAD-dependent desaturase 4 415 5.4E-100 T 12-10-2018 IPR017830 Hydroxysqualene dehydroxylase HpnE MetaCyc: PWY-7072 VAPA_1c41570 6f06848174a191d0b92085c27db215ef 230 SMART SM00382 26 217 5.4E-10 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c41570 6f06848174a191d0b92085c27db215ef 230 TIGRFAM TIGR03410 urea_trans_UrtE: urea ABC transporter, ATP-binding protein UrtE 2 230 3.9E-104 T 12-10-2018 IPR017780 ABC transporter, urea, ATP-binding protein, UrtE VAPA_1c41570 6f06848174a191d0b92085c27db215ef 230 Gene3D G3DSA:3.40.50.300 1 226 9.3E-58 T 12-10-2018 VAPA_1c41570 6f06848174a191d0b92085c27db215ef 230 Pfam PF00005 ABC transporter 17 159 6.4E-33 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c41570 6f06848174a191d0b92085c27db215ef 230 SUPERFAMILY SSF52540 2 215 1.78E-56 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c52760 97fee2618a0558d48400650ffa88df1e 240 Gene3D G3DSA:3.30.420.40 95 182 8.1E-63 T 12-10-2018 VAPA_1c52760 97fee2618a0558d48400650ffa88df1e 240 SUPERFAMILY SSF53067 4 104 1.23E-24 T 12-10-2018 VAPA_1c52760 97fee2618a0558d48400650ffa88df1e 240 SUPERFAMILY SSF53067 110 211 2.33E-15 T 12-10-2018 VAPA_1c52760 97fee2618a0558d48400650ffa88df1e 240 Pfam PF00814 Glycoprotease family 36 130 1.1E-25 T 12-10-2018 IPR000905 Gcp-like domain VAPA_1c52760 97fee2618a0558d48400650ffa88df1e 240 Gene3D G3DSA:3.30.420.40 4 213 8.1E-63 T 12-10-2018 VAPA_1c52760 97fee2618a0558d48400650ffa88df1e 240 TIGRFAM TIGR03725 T6A_YeaZ: tRNA threonylcarbamoyl adenosine modification protein YeaZ 4 213 1.6E-58 T 12-10-2018 IPR022496 tRNA threonylcarbamoyl adenosine modification protein TsaB GO:0002949 VAPA_1c19430 02b57fc011045037fa81d974e21662e3 280 SUPERFAMILY SSF51182 18 203 4.98E-17 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily VAPA_1c19430 02b57fc011045037fa81d974e21662e3 280 Pfam PF02311 AraC-like ligand binding domain 43 121 3.6E-6 T 12-10-2018 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 VAPA_1c19430 02b57fc011045037fa81d974e21662e3 280 Gene3D G3DSA:1.10.10.60 172 278 3.7E-20 T 12-10-2018 VAPA_1c19430 02b57fc011045037fa81d974e21662e3 280 SUPERFAMILY SSF46689 228 273 2.11E-6 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 VAPA_1c19430 02b57fc011045037fa81d974e21662e3 280 SMART SM00342 189 271 3.6E-16 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 VAPA_1c19430 02b57fc011045037fa81d974e21662e3 280 Pfam PF12833 Helix-turn-helix domain 196 272 1.7E-18 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 VAPA_1c19430 02b57fc011045037fa81d974e21662e3 280 Gene3D G3DSA:2.60.120.10 27 104 5.4E-7 T 12-10-2018 IPR014710 RmlC-like jelly roll fold VAPA_1c24050 e77431216f4f4060edc5e92d09e4eb2d 229 Gene3D G3DSA:2.40.50.140 1 72 2.8E-13 T 12-10-2018 VAPA_1c24050 e77431216f4f4060edc5e92d09e4eb2d 229 Pfam PF00313 'Cold-shock' DNA-binding domain 10 66 2.3E-8 T 12-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 VAPA_1c24050 e77431216f4f4060edc5e92d09e4eb2d 229 SUPERFAMILY SSF50249 2 67 1.47E-9 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold VAPA_1c24050 e77431216f4f4060edc5e92d09e4eb2d 229 SMART SM00357 4 68 5.3E-6 T 12-10-2018 IPR011129 Cold shock domain GO:0003676 VAPA_1c24050 e77431216f4f4060edc5e92d09e4eb2d 229 Pfam PF06961 Protein of unknown function (DUF1294) 145 199 3.1E-25 T 12-10-2018 IPR010718 Protein of unknown function DUF1294 VAPA_1c24050 e77431216f4f4060edc5e92d09e4eb2d 229 ProSitePatterns PS00352 'Cold-shock' domain signature. 16 35 - T 12-10-2018 IPR019844 Cold-shock conserved site VAPA_1c32560 5228f2435e4ccd90992179d087f0de55 278 Gene3D G3DSA:3.30.450.40 87 264 1.8E-42 T 12-10-2018 IPR029016 GAF-like domain superfamily VAPA_1c32560 5228f2435e4ccd90992179d087f0de55 278 Gene3D G3DSA:1.10.10.10 3 86 4.9E-23 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c32560 5228f2435e4ccd90992179d087f0de55 278 SMART SM00346 18 108 3.6E-27 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 VAPA_1c32560 5228f2435e4ccd90992179d087f0de55 278 SUPERFAMILY SSF46785 18 91 4.92E-18 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c32560 5228f2435e4ccd90992179d087f0de55 278 Pfam PF01614 Bacterial transcriptional regulator 139 259 3.4E-21 T 12-10-2018 IPR014757 Transcription regulator IclR, C-terminal VAPA_1c32560 5228f2435e4ccd90992179d087f0de55 278 Pfam PF09339 IclR helix-turn-helix domain 20 69 7.9E-15 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 VAPA_1c32560 5228f2435e4ccd90992179d087f0de55 278 SUPERFAMILY SSF55781 84 264 1.31E-42 T 12-10-2018 VAPA_1c10140 9168844ab40da11f65c49fffc8b9c007 462 Gene3D G3DSA:1.20.120.140 5 306 1.0E-113 T 12-10-2018 VAPA_1c10140 9168844ab40da11f65c49fffc8b9c007 462 SMART SM00382 99 272 4.2E-10 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c10140 9168844ab40da11f65c49fffc8b9c007 462 TIGRFAM TIGR00959 ffh: signal recognition particle protein 4 430 4.0E-165 T 12-10-2018 IPR004780 Signal recognition particle protein Ffh GO:0003924|GO:0005525|GO:0006614|GO:0048500 VAPA_1c10140 9168844ab40da11f65c49fffc8b9c007 462 Pfam PF00448 SRP54-type protein, GTPase domain 100 295 4.8E-69 T 12-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 VAPA_1c10140 9168844ab40da11f65c49fffc8b9c007 462 SUPERFAMILY SSF47446 329 432 1.08E-32 T 12-10-2018 IPR036891 Signal recognition particle, SRP54 subunit, M-domain superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 VAPA_1c10140 9168844ab40da11f65c49fffc8b9c007 462 Pfam PF02881 SRP54-type protein, helical bundle domain 5 82 2.6E-19 T 12-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 VAPA_1c10140 9168844ab40da11f65c49fffc8b9c007 462 SMART SM00963 1 86 1.2E-28 T 12-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 VAPA_1c10140 9168844ab40da11f65c49fffc8b9c007 462 Gene3D G3DSA:3.40.50.300 90 285 1.0E-113 T 12-10-2018 VAPA_1c10140 9168844ab40da11f65c49fffc8b9c007 462 Pfam PF02978 Signal peptide binding domain 329 428 1.0E-29 T 12-10-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 VAPA_1c10140 9168844ab40da11f65c49fffc8b9c007 462 Hamap MF_00306 Signal recognition particle 54 kDa protein [srp54]. 5 450 32.036 T 12-10-2018 IPR022941 Signal recognition particle, SRP54 subunit GO:0003924|GO:0005525|GO:0006614|GO:0048500 Reactome: R-HSA-1799339 VAPA_1c10140 9168844ab40da11f65c49fffc8b9c007 462 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 269 282 - T 12-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 VAPA_1c10140 9168844ab40da11f65c49fffc8b9c007 462 Gene3D G3DSA:1.10.260.30 328 453 1.6E-39 T 12-10-2018 IPR036891 Signal recognition particle, SRP54 subunit, M-domain superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 VAPA_1c10140 9168844ab40da11f65c49fffc8b9c007 462 SMART SM00962 100 296 3.7E-107 T 12-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 VAPA_1c10140 9168844ab40da11f65c49fffc8b9c007 462 SUPERFAMILY SSF52540 42 358 6.55E-49 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c28220 2813e765e43c894946bf70455856e5b1 309 Gene3D G3DSA:3.30.479.30 47 179 1.6E-38 T 12-10-2018 VAPA_1c28220 2813e765e43c894946bf70455856e5b1 309 SUPERFAMILY SSF117892 50 183 9.81E-39 T 12-10-2018 IPR036013 Band 7/SPFH domain superfamily VAPA_1c28220 2813e765e43c894946bf70455856e5b1 309 PRINTS PR00721 Stomatin signature 153 171 2.9E-28 T 12-10-2018 IPR001972 Stomatin family GO:0016020 VAPA_1c28220 2813e765e43c894946bf70455856e5b1 309 PRINTS PR00721 Stomatin signature 172 193 2.9E-28 T 12-10-2018 IPR001972 Stomatin family GO:0016020 VAPA_1c28220 2813e765e43c894946bf70455856e5b1 309 PRINTS PR00721 Stomatin signature 129 152 2.9E-28 T 12-10-2018 IPR001972 Stomatin family GO:0016020 VAPA_1c28220 2813e765e43c894946bf70455856e5b1 309 PRINTS PR00721 Stomatin signature 74 95 2.9E-28 T 12-10-2018 IPR001972 Stomatin family GO:0016020 VAPA_1c28220 2813e765e43c894946bf70455856e5b1 309 PRINTS PR00721 Stomatin signature 26 48 2.9E-28 T 12-10-2018 IPR001972 Stomatin family GO:0016020 VAPA_1c28220 2813e765e43c894946bf70455856e5b1 309 PRINTS PR00721 Stomatin signature 109 126 2.9E-28 T 12-10-2018 IPR001972 Stomatin family GO:0016020 VAPA_1c28220 2813e765e43c894946bf70455856e5b1 309 SMART SM00244 19 177 2.4E-56 T 12-10-2018 IPR001107 Band 7 domain VAPA_1c28220 2813e765e43c894946bf70455856e5b1 309 Pfam PF16200 C-terminal region of band_7 242 302 1.3E-19 T 12-10-2018 IPR032435 Band 7, C-terminal extension Reactome: R-HSA-8949664 VAPA_1c28220 2813e765e43c894946bf70455856e5b1 309 Pfam PF01145 SPFH domain / Band 7 family 24 192 5.8E-28 T 12-10-2018 IPR001107 Band 7 domain VAPA_2c00680 6d0bf2f30f8880e3e26b3c267b6309ca 360 Pfam PF16363 GDP-mannose 4,6 dehydratase 3 323 3.8E-100 T 12-10-2018 IPR016040 NAD(P)-binding domain VAPA_2c00680 6d0bf2f30f8880e3e26b3c267b6309ca 360 Gene3D G3DSA:3.90.25.10 200 330 2.2E-130 T 12-10-2018 VAPA_2c00680 6d0bf2f30f8880e3e26b3c267b6309ca 360 TIGRFAM TIGR01181 dTDP_gluc_dehyt: dTDP-glucose 4,6-dehydratase 2 337 3.6E-153 T 12-10-2018 IPR005888 dTDP-glucose 4,6-dehydratase GO:0008460|GO:0009225 KEGG: 00521+4.2.1.46|KEGG: 00523+4.2.1.46|KEGG: 00525+4.2.1.46|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688|MetaCyc: PWY-7814 VAPA_2c00680 6d0bf2f30f8880e3e26b3c267b6309ca 360 SUPERFAMILY SSF51735 2 335 1.27E-89 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_2c00680 6d0bf2f30f8880e3e26b3c267b6309ca 360 Gene3D G3DSA:3.40.50.720 2 322 2.2E-130 T 12-10-2018 VAPA_1c32200 f1ab7ce626a83049c3a2eba381fa1ec0 291 Pfam PF13242 HAD-hyrolase-like 202 250 8.8E-12 T 12-10-2018 VAPA_1c32200 f1ab7ce626a83049c3a2eba381fa1ec0 291 Pfam PF13344 Haloacid dehalogenase-like hydrolase 33 127 1.2E-17 T 12-10-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA VAPA_1c32200 f1ab7ce626a83049c3a2eba381fa1ec0 291 TIGRFAM TIGR01460 HAD-SF-IIA: HAD hydrolase, family IIA 33 249 2.3E-34 T 12-10-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA VAPA_1c32200 f1ab7ce626a83049c3a2eba381fa1ec0 291 SUPERFAMILY SSF56784 30 259 1.33E-45 T 12-10-2018 IPR036412 HAD-like superfamily VAPA_1c32200 f1ab7ce626a83049c3a2eba381fa1ec0 291 Gene3D G3DSA:3.40.50.1000 106 203 2.0E-57 T 12-10-2018 IPR023214 HAD superfamily VAPA_1c32200 f1ab7ce626a83049c3a2eba381fa1ec0 291 Gene3D G3DSA:3.40.50.1000 32 249 2.0E-57 T 12-10-2018 IPR023214 HAD superfamily VAPA_1c48700 26547e8b264fce6b7db872f4036b101c 245 SUPERFAMILY SSF55781 76 242 5.95E-35 T 12-10-2018 VAPA_1c48700 26547e8b264fce6b7db872f4036b101c 245 SMART SM00346 3 93 1.6E-5 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 VAPA_1c48700 26547e8b264fce6b7db872f4036b101c 245 Pfam PF01614 Bacterial transcriptional regulator 122 243 2.2E-20 T 12-10-2018 IPR014757 Transcription regulator IclR, C-terminal VAPA_1c48700 26547e8b264fce6b7db872f4036b101c 245 Gene3D G3DSA:3.30.450.40 78 245 2.2E-35 T 12-10-2018 IPR029016 GAF-like domain superfamily VAPA_1c48700 26547e8b264fce6b7db872f4036b101c 245 Gene3D G3DSA:1.10.10.10 2 77 7.5E-13 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c48700 26547e8b264fce6b7db872f4036b101c 245 Pfam PF09339 IclR helix-turn-helix domain 8 51 6.5E-10 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 VAPA_1c48700 26547e8b264fce6b7db872f4036b101c 245 SUPERFAMILY SSF46785 3 74 2.0E-11 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c48670 d5cb7c6a88c5ebfc0b92ca872b123ff3 408 Pfam PF02515 CoA-transferase family III 7 373 5.4E-107 T 12-10-2018 IPR003673 CoA-transferase family III GO:0003824 VAPA_1c48670 d5cb7c6a88c5ebfc0b92ca872b123ff3 408 Gene3D G3DSA:3.40.50.10540 6 391 1.6E-115 T 12-10-2018 IPR023606 CoA-transferase family III domain superfamily VAPA_1c48670 d5cb7c6a88c5ebfc0b92ca872b123ff3 408 SUPERFAMILY SSF89796 2 397 2.75E-122 T 12-10-2018 IPR023606 CoA-transferase family III domain superfamily VAPA_1c48670 d5cb7c6a88c5ebfc0b92ca872b123ff3 408 Gene3D G3DSA:3.30.1540.10 233 325 1.6E-115 T 12-10-2018 VAPA_2c09690 460166d0a98656cbb5baf393e9b36db1 337 SUPERFAMILY SSF63380 100 194 9.85E-22 T 12-10-2018 IPR017938 Riboflavin synthase-like beta-barrel VAPA_2c09690 460166d0a98656cbb5baf393e9b36db1 337 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 37 45 - T 12-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 VAPA_2c09690 460166d0a98656cbb5baf393e9b36db1 337 PRINTS PR00410 Phenol hydroxylase reductase family signature 189 198 2.6E-23 T 12-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 VAPA_2c09690 460166d0a98656cbb5baf393e9b36db1 337 PRINTS PR00410 Phenol hydroxylase reductase family signature 146 153 2.6E-23 T 12-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 VAPA_2c09690 460166d0a98656cbb5baf393e9b36db1 337 PRINTS PR00410 Phenol hydroxylase reductase family signature 205 224 2.6E-23 T 12-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 VAPA_2c09690 460166d0a98656cbb5baf393e9b36db1 337 PRINTS PR00410 Phenol hydroxylase reductase family signature 130 142 2.6E-23 T 12-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 VAPA_2c09690 460166d0a98656cbb5baf393e9b36db1 337 PRINTS PR00410 Phenol hydroxylase reductase family signature 230 239 2.6E-23 T 12-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 VAPA_2c09690 460166d0a98656cbb5baf393e9b36db1 337 PRINTS PR00410 Phenol hydroxylase reductase family signature 296 304 2.6E-23 T 12-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 VAPA_2c09690 460166d0a98656cbb5baf393e9b36db1 337 SUPERFAMILY SSF52343 199 330 3.01E-33 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain VAPA_2c09690 460166d0a98656cbb5baf393e9b36db1 337 SUPERFAMILY SSF54292 1 86 5.64E-21 T 12-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 VAPA_2c09690 460166d0a98656cbb5baf393e9b36db1 337 Pfam PF00175 Oxidoreductase NAD-binding domain 206 310 2.8E-17 T 12-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 VAPA_2c09690 460166d0a98656cbb5baf393e9b36db1 337 Gene3D G3DSA:3.40.50.80 197 330 1.9E-29 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain VAPA_2c09690 460166d0a98656cbb5baf393e9b36db1 337 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 205 224 4.1E-5 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 VAPA_2c09690 460166d0a98656cbb5baf393e9b36db1 337 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 296 304 4.1E-5 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 VAPA_2c09690 460166d0a98656cbb5baf393e9b36db1 337 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 146 153 4.1E-5 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 VAPA_2c09690 460166d0a98656cbb5baf393e9b36db1 337 Gene3D G3DSA:3.10.20.30 4 99 3.0E-20 T 12-10-2018 IPR012675 Beta-grasp domain superfamily VAPA_2c09690 460166d0a98656cbb5baf393e9b36db1 337 Gene3D G3DSA:2.40.30.10 102 196 2.3E-21 T 12-10-2018 VAPA_2c09690 460166d0a98656cbb5baf393e9b36db1 337 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 6 79 4.0E-12 T 12-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 VAPA_2c09690 460166d0a98656cbb5baf393e9b36db1 337 Pfam PF00970 Oxidoreductase FAD-binding domain 105 194 3.8E-14 T 12-10-2018 IPR008333 Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain Reactome: R-HSA-1237044 VAPA_1c01260 88dbc1b8845001f9d507a4b0e10bacd8 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 44 55 6.4E-9 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c01260 88dbc1b8845001f9d507a4b0e10bacd8 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 23 34 6.4E-9 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c01260 88dbc1b8845001f9d507a4b0e10bacd8 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 44 6.4E-9 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c01260 88dbc1b8845001f9d507a4b0e10bacd8 302 Pfam PF03466 LysR substrate binding domain 90 297 5.3E-37 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_1c01260 88dbc1b8845001f9d507a4b0e10bacd8 302 Gene3D G3DSA:3.40.190.10 168 266 1.2E-51 T 12-10-2018 VAPA_1c01260 88dbc1b8845001f9d507a4b0e10bacd8 302 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 9 66 3.3E-19 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c01260 88dbc1b8845001f9d507a4b0e10bacd8 302 Gene3D G3DSA:3.40.190.10 104 293 1.2E-51 T 12-10-2018 VAPA_1c01260 88dbc1b8845001f9d507a4b0e10bacd8 302 SUPERFAMILY SSF53850 84 298 5.25E-37 T 12-10-2018 VAPA_1c01260 88dbc1b8845001f9d507a4b0e10bacd8 302 Gene3D G3DSA:1.10.10.10 7 90 5.1E-21 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c01260 88dbc1b8845001f9d507a4b0e10bacd8 302 SUPERFAMILY SSF46785 3 82 1.14E-20 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c48110 1cf23d13978b0e8cdfc81519a43310db 705 SUPERFAMILY SSF52210 310 462 8.5E-20 T 12-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 VAPA_1c48110 1cf23d13978b0e8cdfc81519a43310db 705 SMART SM00881 16 111 5.5E-29 T 12-10-2018 IPR003781 CoA-binding GO:0048037 VAPA_1c48110 1cf23d13978b0e8cdfc81519a43310db 705 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 166 302 2.4E-50 T 12-10-2018 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain VAPA_1c48110 1cf23d13978b0e8cdfc81519a43310db 705 Gene3D G3DSA:3.30.470.20 487 700 2.3E-73 T 12-10-2018 VAPA_1c48110 1cf23d13978b0e8cdfc81519a43310db 705 Gene3D G3DSA:3.40.50.261 309 472 2.9E-20 T 12-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 VAPA_1c48110 1cf23d13978b0e8cdfc81519a43310db 705 SUPERFAMILY SSF51735 8 147 4.85E-33 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c48110 1cf23d13978b0e8cdfc81519a43310db 705 SUPERFAMILY SSF52210 142 302 4.71E-41 T 12-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 VAPA_1c48110 1cf23d13978b0e8cdfc81519a43310db 705 Gene3D G3DSA:3.30.1490.20 505 582 2.3E-73 T 12-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 VAPA_1c48110 1cf23d13978b0e8cdfc81519a43310db 705 Gene3D G3DSA:3.40.50.720 12 140 3.8E-37 T 12-10-2018 VAPA_1c48110 1cf23d13978b0e8cdfc81519a43310db 705 Pfam PF13380 CoA binding domain 20 145 5.4E-20 T 12-10-2018 IPR003781 CoA-binding GO:0048037 VAPA_1c48110 1cf23d13978b0e8cdfc81519a43310db 705 Gene3D G3DSA:3.40.50.261 141 307 7.6E-56 T 12-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 VAPA_1c48110 1cf23d13978b0e8cdfc81519a43310db 705 SUPERFAMILY SSF56059 488 701 2.87E-38 T 12-10-2018 VAPA_1c48110 1cf23d13978b0e8cdfc81519a43310db 705 Pfam PF13549 ATP-grasp domain 486 700 1.3E-61 T 12-10-2018 VAPA_1c12050 614c50762c4ce876f0fa9b304c28d310 370 SUPERFAMILY SSF56796 16 363 2.49E-114 T 12-10-2018 VAPA_1c12050 614c50762c4ce876f0fa9b304c28d310 370 Hamap MF_00110 3-dehydroquinate synthase [aroB]. 10 368 70.592 T 12-10-2018 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 VAPA_1c12050 614c50762c4ce876f0fa9b304c28d310 370 Gene3D G3DSA:3.40.50.1970 5 181 1.2E-64 T 12-10-2018 VAPA_1c12050 614c50762c4ce876f0fa9b304c28d310 370 TIGRFAM TIGR01357 aroB: 3-dehydroquinate synthase 22 354 1.3E-114 T 12-10-2018 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 VAPA_1c12050 614c50762c4ce876f0fa9b304c28d310 370 Gene3D G3DSA:1.20.1090.10 182 368 1.1E-63 T 12-10-2018 VAPA_1c12050 614c50762c4ce876f0fa9b304c28d310 370 Pfam PF01761 3-dehydroquinate synthase 77 333 3.5E-106 T 12-10-2018 IPR030960 3-dehydroquinate synthase domain KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 VAPA_1c12050 614c50762c4ce876f0fa9b304c28d310 370 PIRSF PIRSF001455 22 369 2.1E-108 T 12-10-2018 IPR030963 3-dehydroquinate synthase family GO:0009073|GO:0016838 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 VAPA_1c18150 290f52e7f2eb34894ee65202ab3ef873 271 Gene3D G3DSA:1.20.120.530 112 264 1.4E-33 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal VAPA_1c18150 290f52e7f2eb34894ee65202ab3ef873 271 SMART SM00895 120 247 1.6E-24 T 12-10-2018 IPR011711 GntR, C-terminal VAPA_1c18150 290f52e7f2eb34894ee65202ab3ef873 271 Pfam PF07729 FCD domain 121 246 5.8E-26 T 12-10-2018 IPR011711 GntR, C-terminal VAPA_1c18150 290f52e7f2eb34894ee65202ab3ef873 271 SMART SM00345 37 96 3.3E-23 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_1c18150 290f52e7f2eb34894ee65202ab3ef873 271 Pfam PF00392 Bacterial regulatory proteins, gntR family 36 96 3.2E-22 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_1c18150 290f52e7f2eb34894ee65202ab3ef873 271 SUPERFAMILY SSF46785 27 100 1.78E-20 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c18150 290f52e7f2eb34894ee65202ab3ef873 271 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 70 86 6.2E-9 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_1c18150 290f52e7f2eb34894ee65202ab3ef873 271 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 56 70 6.2E-9 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_1c18150 290f52e7f2eb34894ee65202ab3ef873 271 Gene3D G3DSA:1.10.10.10 25 99 2.8E-22 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c18150 290f52e7f2eb34894ee65202ab3ef873 271 SUPERFAMILY SSF48008 117 253 1.05E-28 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal VAPA_1c20450 376a3feffb03f1f1eace947ee2f7ad75 267 Gene3D G3DSA:1.10.12.10 210 262 2.1E-7 T 12-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal VAPA_1c20450 376a3feffb03f1f1eace947ee2f7ad75 267 SUPERFAMILY SSF52096 1 262 7.08E-75 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily VAPA_1c20450 376a3feffb03f1f1eace947ee2f7ad75 267 Pfam PF00378 Enoyl-CoA hydratase/isomerase 11 260 7.0E-53 T 12-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 VAPA_1c20450 376a3feffb03f1f1eace947ee2f7ad75 267 Gene3D G3DSA:3.90.226.10 1 207 6.3E-65 T 12-10-2018 VAPA_1c28420 d1b9acac9e57241c56d4a572f67ba056 406 Gene3D G3DSA:3.40.640.10 43 290 3.1E-110 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 VAPA_1c28420 d1b9acac9e57241c56d4a572f67ba056 406 Gene3D G3DSA:3.90.1150.10 13 387 3.1E-110 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 VAPA_1c28420 d1b9acac9e57241c56d4a572f67ba056 406 TIGRFAM TIGR03538 DapC_gpp: succinyldiaminopimelate transaminase 1 398 2.4E-178 T 12-10-2018 IPR019878 Succinyldiaminopimelate transaminase, DapC, beta/gammaproteobacteria GO:0009016|GO:0009089 VAPA_1c28420 d1b9acac9e57241c56d4a572f67ba056 406 Pfam PF00155 Aminotransferase class I and II 32 394 1.1E-44 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 VAPA_1c28420 d1b9acac9e57241c56d4a572f67ba056 406 SUPERFAMILY SSF53383 2 399 2.04E-83 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase VAPA_1c53460 88c569b07b772ce9c2b51f3c52b818d2 208 Pfam PF00196 Bacterial regulatory proteins, luxR family 150 203 3.8E-20 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_1c53460 88c569b07b772ce9c2b51f3c52b818d2 208 SUPERFAMILY SSF46894 139 206 5.1E-19 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 VAPA_1c53460 88c569b07b772ce9c2b51f3c52b818d2 208 SMART SM00421 148 205 1.6E-20 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_1c53460 88c569b07b772ce9c2b51f3c52b818d2 208 Gene3D G3DSA:1.10.10.10 143 206 4.9E-21 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c53460 88c569b07b772ce9c2b51f3c52b818d2 208 Pfam PF00072 Response regulator receiver domain 9 124 6.4E-21 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_1c53460 88c569b07b772ce9c2b51f3c52b818d2 208 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 151 165 3.4E-12 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_1c53460 88c569b07b772ce9c2b51f3c52b818d2 208 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 181 193 3.4E-12 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_1c53460 88c569b07b772ce9c2b51f3c52b818d2 208 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 165 181 3.4E-12 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_1c53460 88c569b07b772ce9c2b51f3c52b818d2 208 SMART SM00448 7 124 3.8E-21 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_1c53460 88c569b07b772ce9c2b51f3c52b818d2 208 Gene3D G3DSA:3.40.50.2300 5 137 1.9E-41 T 12-10-2018 VAPA_1c53460 88c569b07b772ce9c2b51f3c52b818d2 208 ProSitePatterns PS00622 LuxR-type HTH domain signature. 165 192 - T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_1c53460 88c569b07b772ce9c2b51f3c52b818d2 208 SUPERFAMILY SSF52172 9 150 2.28E-27 T 12-10-2018 IPR011006 CheY-like superfamily VAPA_1c29700 a853450e661c4d9e2d44d140b27adc87 236 Pfam PF04402 Protein of unknown function (DUF541) 36 230 4.6E-28 T 12-10-2018 IPR007497 Protein of unknown function DUF541 VAPA_1c29700 a853450e661c4d9e2d44d140b27adc87 236 Gene3D G3DSA:3.30.110.170 38 230 2.0E-23 T 12-10-2018 VAPA_1c29700 a853450e661c4d9e2d44d140b27adc87 236 Gene3D G3DSA:3.30.70.2970 47 150 2.0E-23 T 12-10-2018 VAPA_1c40510 5c88720f5b54656cd77dfba4a3f694b4 221 Gene3D G3DSA:1.20.120.530 70 209 5.6E-25 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal VAPA_1c40510 5c88720f5b54656cd77dfba4a3f694b4 221 Gene3D G3DSA:1.10.10.10 1 69 2.7E-19 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c40510 5c88720f5b54656cd77dfba4a3f694b4 221 SMART SM00345 9 67 7.6E-15 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_1c40510 5c88720f5b54656cd77dfba4a3f694b4 221 Pfam PF00392 Bacterial regulatory proteins, gntR family 6 67 5.3E-16 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_1c40510 5c88720f5b54656cd77dfba4a3f694b4 221 SMART SM00895 77 200 7.5E-19 T 12-10-2018 IPR011711 GntR, C-terminal VAPA_1c40510 5c88720f5b54656cd77dfba4a3f694b4 221 Pfam PF07729 FCD domain 77 199 2.0E-24 T 12-10-2018 IPR011711 GntR, C-terminal VAPA_1c40510 5c88720f5b54656cd77dfba4a3f694b4 221 SUPERFAMILY SSF48008 73 205 4.71E-27 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal VAPA_1c40510 5c88720f5b54656cd77dfba4a3f694b4 221 SUPERFAMILY SSF46785 5 71 1.4E-17 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c41810 177c8a572dbf7472df1410754abc61f7 225 SUPERFAMILY SSF102712 114 195 4.97E-5 T 12-10-2018 VAPA_1c41810 177c8a572dbf7472df1410754abc61f7 225 Pfam PF04002 RadC-like JAB domain 105 224 1.2E-41 T 12-10-2018 IPR025657 RadC-like JAB domain VAPA_1c41810 177c8a572dbf7472df1410754abc61f7 225 SUPERFAMILY SSF47781 17 76 1.27E-6 T 12-10-2018 IPR010994 RuvA domain 2-like VAPA_1c41810 177c8a572dbf7472df1410754abc61f7 225 Gene3D G3DSA:3.40.140.10 101 225 6.4E-41 T 12-10-2018 VAPA_1c41810 177c8a572dbf7472df1410754abc61f7 225 ProSitePatterns PS01302 Uncharacterized protein family UPF0758 signature. 174 179 - T 12-10-2018 IPR020891 Uncharacterised protein family UPF0758, conserved site VAPA_1c41810 177c8a572dbf7472df1410754abc61f7 225 TIGRFAM TIGR00608 radc: DNA repair protein RadC 11 225 1.8E-67 T 12-10-2018 IPR001405 Uncharacterised protein family UPF0758 VAPA_1c42550 145e90ec62f8264b6796afae28d3665d 154 Hamap MF_00821 Protein-export protein SecB [secB]. 1 145 31.206 T 12-10-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 VAPA_1c42550 145e90ec62f8264b6796afae28d3665d 154 SUPERFAMILY SSF54611 2 141 6.1E-51 T 12-10-2018 IPR035958 SecB-like superfamily VAPA_1c42550 145e90ec62f8264b6796afae28d3665d 154 Pfam PF02556 Preprotein translocase subunit SecB 4 143 1.4E-55 T 12-10-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 VAPA_1c42550 145e90ec62f8264b6796afae28d3665d 154 Gene3D G3DSA:3.10.420.10 1 150 2.4E-54 T 12-10-2018 IPR035958 SecB-like superfamily VAPA_1c42550 145e90ec62f8264b6796afae28d3665d 154 PRINTS PR01594 Bacterial protein-transport SecB chaperone protein signature 73 93 1.0E-29 T 12-10-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 VAPA_1c42550 145e90ec62f8264b6796afae28d3665d 154 PRINTS PR01594 Bacterial protein-transport SecB chaperone protein signature 13 30 1.0E-29 T 12-10-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 VAPA_1c42550 145e90ec62f8264b6796afae28d3665d 154 PRINTS PR01594 Bacterial protein-transport SecB chaperone protein signature 97 119 1.0E-29 T 12-10-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 VAPA_1c42550 145e90ec62f8264b6796afae28d3665d 154 PRINTS PR01594 Bacterial protein-transport SecB chaperone protein signature 123 141 1.0E-29 T 12-10-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 VAPA_1c42550 145e90ec62f8264b6796afae28d3665d 154 TIGRFAM TIGR00809 secB: protein-export chaperone SecB 7 142 3.2E-46 T 12-10-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 VAPA_1c30480 71789a038ba90d8354d2d5a53d2f17ec 1051 SUPERFAMILY SSF82714 198 279 5.23E-14 T 12-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains VAPA_1c30480 71789a038ba90d8354d2d5a53d2f17ec 1051 SUPERFAMILY SSF82866 312 515 1.05E-32 T 12-10-2018 VAPA_1c30480 71789a038ba90d8354d2d5a53d2f17ec 1051 PRINTS PR00702 Acriflavin resistance protein family signature 463 486 1.6E-18 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 VAPA_1c30480 71789a038ba90d8354d2d5a53d2f17ec 1051 PRINTS PR00702 Acriflavin resistance protein family signature 410 434 1.6E-18 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 VAPA_1c30480 71789a038ba90d8354d2d5a53d2f17ec 1051 PRINTS PR00702 Acriflavin resistance protein family signature 51 69 1.6E-18 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 VAPA_1c30480 71789a038ba90d8354d2d5a53d2f17ec 1051 PRINTS PR00702 Acriflavin resistance protein family signature 382 403 1.6E-18 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 VAPA_1c30480 71789a038ba90d8354d2d5a53d2f17ec 1051 PRINTS PR00702 Acriflavin resistance protein family signature 488 511 1.6E-18 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 VAPA_1c30480 71789a038ba90d8354d2d5a53d2f17ec 1051 PRINTS PR00702 Acriflavin resistance protein family signature 23 47 1.6E-18 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 VAPA_1c30480 71789a038ba90d8354d2d5a53d2f17ec 1051 SUPERFAMILY SSF82693 582 673 7.32E-6 T 12-10-2018 VAPA_1c30480 71789a038ba90d8354d2d5a53d2f17ec 1051 Gene3D G3DSA:3.30.70.1430 53 826 5.9E-250 T 12-10-2018 VAPA_1c30480 71789a038ba90d8354d2d5a53d2f17ec 1051 SUPERFAMILY SSF82714 732 816 6.8E-15 T 12-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains VAPA_1c30480 71789a038ba90d8354d2d5a53d2f17ec 1051 SUPERFAMILY SSF82693 149 337 7.59E-18 T 12-10-2018 VAPA_1c30480 71789a038ba90d8354d2d5a53d2f17ec 1051 SUPERFAMILY SSF82866 817 1042 2.62E-41 T 12-10-2018 VAPA_1c30480 71789a038ba90d8354d2d5a53d2f17ec 1051 SUPERFAMILY SSF82693 53 148 2.62E-19 T 12-10-2018 VAPA_1c30480 71789a038ba90d8354d2d5a53d2f17ec 1051 Gene3D G3DSA:3.30.70.1440 679 882 5.9E-250 T 12-10-2018 VAPA_1c30480 71789a038ba90d8354d2d5a53d2f17ec 1051 Gene3D G3DSA:3.30.2090.10 730 818 5.9E-250 T 12-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains VAPA_1c30480 71789a038ba90d8354d2d5a53d2f17ec 1051 Gene3D G3DSA:1.20.1640.10 29 528 5.9E-250 T 12-10-2018 VAPA_1c30480 71789a038ba90d8354d2d5a53d2f17ec 1051 Pfam PF00873 AcrB/AcrD/AcrF family 17 1035 5.5E-162 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 VAPA_1c30480 71789a038ba90d8354d2d5a53d2f17ec 1051 Gene3D G3DSA:3.30.70.1430 580 678 5.9E-250 T 12-10-2018 VAPA_1c30480 71789a038ba90d8354d2d5a53d2f17ec 1051 Gene3D G3DSA:1.20.1640.10 529 1034 5.9E-250 T 12-10-2018 VAPA_1c30480 71789a038ba90d8354d2d5a53d2f17ec 1051 Gene3D G3DSA:3.30.70.1320 149 340 5.9E-250 T 12-10-2018 VAPA_1c30480 71789a038ba90d8354d2d5a53d2f17ec 1051 Gene3D G3DSA:3.30.2090.10 192 282 5.9E-250 T 12-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains VAPA_1c25580 8d0abac0b260beafe614c0e5d9b3f4d4 321 Gene3D G3DSA:3.40.50.10490 103 285 4.9E-34 T 12-10-2018 VAPA_1c25580 8d0abac0b260beafe614c0e5d9b3f4d4 321 SUPERFAMILY SSF53697 108 269 1.65E-23 T 12-10-2018 VAPA_1c25580 8d0abac0b260beafe614c0e5d9b3f4d4 321 Pfam PF01380 SIS domain 137 251 2.5E-11 T 12-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 VAPA_1c25580 8d0abac0b260beafe614c0e5d9b3f4d4 321 Gene3D G3DSA:1.10.10.10 7 87 1.1E-18 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c25580 8d0abac0b260beafe614c0e5d9b3f4d4 321 SUPERFAMILY SSF46689 12 83 7.53E-17 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 VAPA_1c25580 8d0abac0b260beafe614c0e5d9b3f4d4 321 Pfam PF01418 Helix-turn-helix domain, rpiR family 12 80 1.1E-14 T 12-10-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 VAPA_1c42050 942dd7e218b4985902af46f5ef2e6c23 507 SUPERFAMILY SSF103473 4 493 9.16E-52 T 12-10-2018 IPR036259 MFS transporter superfamily VAPA_1c42050 942dd7e218b4985902af46f5ef2e6c23 507 Gene3D G3DSA:1.20.1250.20 196 423 8.4E-12 T 12-10-2018 VAPA_1c42050 942dd7e218b4985902af46f5ef2e6c23 507 Gene3D G3DSA:1.20.1250.20 4 195 1.2E-32 T 12-10-2018 VAPA_1c42050 942dd7e218b4985902af46f5ef2e6c23 507 Pfam PF07690 Major Facilitator Superfamily 16 405 1.3E-40 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 VAPA_1c40420 953cefa2cd8fe9af8363e99419339706 913 SUPERFAMILY SSF81665 56 911 1.57E-97 T 12-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 VAPA_1c40420 953cefa2cd8fe9af8363e99419339706 913 Pfam PF00689 Cation transporting ATPase, C-terminus 737 903 1.8E-10 T 12-10-2018 IPR006068 Cation-transporting P-type ATPase, C-terminal Reactome: R-HSA-936837 VAPA_1c40420 953cefa2cd8fe9af8363e99419339706 913 SUPERFAMILY SSF56784 376 754 4.86E-38 T 12-10-2018 IPR036412 HAD-like superfamily VAPA_1c40420 953cefa2cd8fe9af8363e99419339706 913 Gene3D G3DSA:1.20.1110.10 694 773 2.7E-57 T 12-10-2018 VAPA_1c40420 953cefa2cd8fe9af8363e99419339706 913 Gene3D G3DSA:3.40.1110.10 425 561 2.7E-57 T 12-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 VAPA_1c40420 953cefa2cd8fe9af8363e99419339706 913 TIGRFAM TIGR01524 ATPase-IIIB_Mg: magnesium-translocating P-type ATPase 45 913 0.0 T 12-10-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 VAPA_1c40420 953cefa2cd8fe9af8363e99419339706 913 Pfam PF00702 haloacid dehalogenase-like hydrolase 374 668 1.2E-18 T 12-10-2018 VAPA_1c40420 953cefa2cd8fe9af8363e99419339706 913 Gene3D G3DSA:3.40.50.1000 562 693 2.7E-57 T 12-10-2018 IPR023214 HAD superfamily VAPA_1c40420 953cefa2cd8fe9af8363e99419339706 913 PRINTS PR01836 Magnesium-transporting ATPase signature 782 798 1.6E-78 T 12-10-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 VAPA_1c40420 953cefa2cd8fe9af8363e99419339706 913 PRINTS PR01836 Magnesium-transporting ATPase signature 730 741 1.6E-78 T 12-10-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 VAPA_1c40420 953cefa2cd8fe9af8363e99419339706 913 PRINTS PR01836 Magnesium-transporting ATPase signature 712 727 1.6E-78 T 12-10-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 VAPA_1c40420 953cefa2cd8fe9af8363e99419339706 913 PRINTS PR01836 Magnesium-transporting ATPase signature 817 838 1.6E-78 T 12-10-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 VAPA_1c40420 953cefa2cd8fe9af8363e99419339706 913 PRINTS PR01836 Magnesium-transporting ATPase signature 291 307 1.6E-78 T 12-10-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 VAPA_1c40420 953cefa2cd8fe9af8363e99419339706 913 PRINTS PR01836 Magnesium-transporting ATPase signature 867 888 1.6E-78 T 12-10-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 VAPA_1c40420 953cefa2cd8fe9af8363e99419339706 913 PRINTS PR01836 Magnesium-transporting ATPase signature 412 425 1.6E-78 T 12-10-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 VAPA_1c40420 953cefa2cd8fe9af8363e99419339706 913 PRINTS PR01836 Magnesium-transporting ATPase signature 308 327 1.6E-78 T 12-10-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 VAPA_1c40420 953cefa2cd8fe9af8363e99419339706 913 PRINTS PR01836 Magnesium-transporting ATPase signature 762 775 1.6E-78 T 12-10-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 VAPA_1c40420 953cefa2cd8fe9af8363e99419339706 913 SMART SM00831 51 124 8.9E-10 T 12-10-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 VAPA_1c40420 953cefa2cd8fe9af8363e99419339706 913 Gene3D G3DSA:1.20.1110.10 102 374 4.0E-83 T 12-10-2018 VAPA_1c40420 953cefa2cd8fe9af8363e99419339706 913 Pfam PF00690 Cation transporter/ATPase, N-terminus 59 119 4.8E-16 T 12-10-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 VAPA_1c40420 953cefa2cd8fe9af8363e99419339706 913 Pfam PF00122 E1-E2 ATPase 179 358 4.2E-42 T 12-10-2018 VAPA_1c40420 953cefa2cd8fe9af8363e99419339706 913 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 625 743 2.5E-28 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 VAPA_1c40420 953cefa2cd8fe9af8363e99419339706 913 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 279 416 1.3E-20 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 VAPA_1c40420 953cefa2cd8fe9af8363e99419339706 913 Gene3D G3DSA:3.40.50.1000 375 387 4.0E-83 T 12-10-2018 IPR023214 HAD superfamily VAPA_1c40420 953cefa2cd8fe9af8363e99419339706 913 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 380 386 - T 12-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 VAPA_1c40420 953cefa2cd8fe9af8363e99419339706 913 SUPERFAMILY SSF81653 178 277 1.7E-26 T 12-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 VAPA_1c40420 953cefa2cd8fe9af8363e99419339706 913 Gene3D G3DSA:2.70.150.10 67 281 4.0E-83 T 12-10-2018 VAPA_1c53580 41763431bfa456cbb04f0e5069a2fab3 459 Pfam PF00206 Lyase 14 316 1.4E-54 T 12-10-2018 IPR022761 Fumarate lyase, N-terminal VAPA_1c53580 41763431bfa456cbb04f0e5069a2fab3 459 Gene3D G3DSA:1.10.275.10 1 116 3.7E-37 T 12-10-2018 IPR024083 Fumarase/histidase, N-terminal VAPA_1c53580 41763431bfa456cbb04f0e5069a2fab3 459 Gene3D G3DSA:1.20.200.10 117 450 2.3E-145 T 12-10-2018 VAPA_1c53580 41763431bfa456cbb04f0e5069a2fab3 459 Pfam PF08328 Adenylosuccinate lyase C-terminal 335 449 1.6E-48 T 12-10-2018 IPR013539 Adenylosuccinate lyase PurB, C-terminal GO:0004018|GO:0006188 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234 VAPA_1c53580 41763431bfa456cbb04f0e5069a2fab3 459 PRINTS PR00149 Fumarate lyase superfamily signature 298 314 2.9E-19 T 12-10-2018 IPR000362 Fumarate lyase family VAPA_1c53580 41763431bfa456cbb04f0e5069a2fab3 459 PRINTS PR00149 Fumarate lyase superfamily signature 255 282 2.9E-19 T 12-10-2018 IPR000362 Fumarate lyase family VAPA_1c53580 41763431bfa456cbb04f0e5069a2fab3 459 PRINTS PR00149 Fumarate lyase superfamily signature 116 134 2.9E-19 T 12-10-2018 IPR000362 Fumarate lyase family VAPA_1c53580 41763431bfa456cbb04f0e5069a2fab3 459 PRINTS PR00149 Fumarate lyase superfamily signature 162 180 2.9E-19 T 12-10-2018 IPR000362 Fumarate lyase family VAPA_1c53580 41763431bfa456cbb04f0e5069a2fab3 459 TIGRFAM TIGR00928 purB: adenylosuccinate lyase 12 458 2.9E-118 T 12-10-2018 IPR004769 Adenylosuccinate lyase GO:0004018|GO:0009152 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 VAPA_1c53580 41763431bfa456cbb04f0e5069a2fab3 459 SUPERFAMILY SSF48557 10 458 1.57E-101 T 12-10-2018 IPR008948 L-Aspartase-like GO:0003824 VAPA_1c53580 41763431bfa456cbb04f0e5069a2fab3 459 ProSitePatterns PS00163 Fumarate lyases signature. 298 307 - T 12-10-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 VAPA_1c53580 41763431bfa456cbb04f0e5069a2fab3 459 Gene3D G3DSA:1.10.40.30 386 449 2.3E-145 T 12-10-2018 VAPA_1c14150 672e8590a4c343f97ab31805fb4f759a 147 Gene3D G3DSA:1.10.260.40 1 80 3.1E-29 T 12-10-2018 VAPA_1c14150 672e8590a4c343f97ab31805fb4f759a 147 TIGRFAM TIGR00673 cynS: cyanase 4 147 1.5E-51 T 12-10-2018 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00910+4.2.1.104 VAPA_1c14150 672e8590a4c343f97ab31805fb4f759a 147 Pfam PF02560 Cyanate lyase C-terminal domain 79 145 2.2E-35 T 12-10-2018 IPR003712 Cyanate lyase, C-terminal GO:0009439 KEGG: 00910+4.2.1.104 VAPA_1c14150 672e8590a4c343f97ab31805fb4f759a 147 SMART SM01116 75 147 6.7E-51 T 12-10-2018 IPR003712 Cyanate lyase, C-terminal GO:0009439 KEGG: 00910+4.2.1.104 VAPA_1c14150 672e8590a4c343f97ab31805fb4f759a 147 SUPERFAMILY SSF47413 1 77 1.65E-19 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 VAPA_1c14150 672e8590a4c343f97ab31805fb4f759a 147 PIRSF PIRSF001263 1 147 1.3E-49 T 12-10-2018 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00910+4.2.1.104 VAPA_1c14150 672e8590a4c343f97ab31805fb4f759a 147 Hamap MF_00535 Cyanate hydratase [cynS]. 1 147 82.195 T 12-10-2018 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00910+4.2.1.104 VAPA_1c14150 672e8590a4c343f97ab31805fb4f759a 147 PRINTS PR01693 Cyanase signature 83 97 6.3E-28 T 12-10-2018 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00910+4.2.1.104 VAPA_1c14150 672e8590a4c343f97ab31805fb4f759a 147 PRINTS PR01693 Cyanase signature 34 51 6.3E-28 T 12-10-2018 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00910+4.2.1.104 VAPA_1c14150 672e8590a4c343f97ab31805fb4f759a 147 PRINTS PR01693 Cyanase signature 14 29 6.3E-28 T 12-10-2018 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00910+4.2.1.104 VAPA_1c14150 672e8590a4c343f97ab31805fb4f759a 147 PRINTS PR01693 Cyanase signature 132 142 6.3E-28 T 12-10-2018 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00910+4.2.1.104 VAPA_1c14150 672e8590a4c343f97ab31805fb4f759a 147 PRINTS PR01693 Cyanase signature 101 117 6.3E-28 T 12-10-2018 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00910+4.2.1.104 VAPA_1c14150 672e8590a4c343f97ab31805fb4f759a 147 Gene3D G3DSA:3.30.1160.10 81 147 3.2E-34 T 12-10-2018 IPR036581 Cyanate lyase, C-terminal domain superfamily GO:0009439 KEGG: 00910+4.2.1.104 VAPA_1c14150 672e8590a4c343f97ab31805fb4f759a 147 SUPERFAMILY SSF55234 80 147 1.44E-30 T 12-10-2018 IPR036581 Cyanate lyase, C-terminal domain superfamily GO:0009439 KEGG: 00910+4.2.1.104 VAPA_1c22890 41ecec64de467a73db07e291ccf65522 322 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 44 317 1.3E-76 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c22890 41ecec64de467a73db07e291ccf65522 322 SUPERFAMILY SSF53850 113 284 7.96E-8 T 12-10-2018 VAPA_1c22890 41ecec64de467a73db07e291ccf65522 322 Gene3D G3DSA:3.40.190.150 25 311 1.6E-101 T 12-10-2018 VAPA_1c22890 41ecec64de467a73db07e291ccf65522 322 PIRSF PIRSF017082 2 320 2.7E-70 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c22890 41ecec64de467a73db07e291ccf65522 322 Gene3D G3DSA:3.40.190.10 123 246 1.6E-101 T 12-10-2018 VAPA_1c32890 22e98a176366a655c527cb7b26653187 764 SUPERFAMILY SSF52540 553 732 2.48E-37 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c32890 22e98a176366a655c527cb7b26653187 764 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 555 726 4.3E-11 T 12-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain VAPA_1c32890 22e98a176366a655c527cb7b26653187 764 Pfam PF13807 G-rich domain on putative tyrosine kinase 396 475 5.0E-25 T 12-10-2018 IPR032807 Tyrosine kinase, G-rich domain VAPA_1c32890 22e98a176366a655c527cb7b26653187 764 TIGRFAM TIGR01005 eps_transp_fam: exopolysaccharide transport protein family 27 742 9.3E-125 T 12-10-2018 IPR005700 Exopolysaccharide biosynthesis protein ExoP-like GO:0045226 VAPA_1c32890 22e98a176366a655c527cb7b26653187 764 Gene3D G3DSA:3.40.50.300 468 743 5.4E-68 T 12-10-2018 VAPA_1c32890 22e98a176366a655c527cb7b26653187 764 TIGRFAM TIGR01007 eps_fam: capsular exopolysaccharide family 535 735 5.5E-44 T 12-10-2018 IPR005702 Exopolysaccharide synthesis protein GO:0045226 VAPA_1c32890 22e98a176366a655c527cb7b26653187 764 Pfam PF02706 Chain length determinant protein 28 115 1.5E-11 T 12-10-2018 IPR003856 Polysaccharide chain length determinant N-terminal domain GO:0009103|GO:0016020 VAPA_1c43620 5eab5eb44771ecac0740d97c87f0e187 423 Hamap MF_00087 Glutamyl-tRNA reductase [hemA]. 2 418 28.263 T 12-10-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 VAPA_1c43620 5eab5eb44771ecac0740d97c87f0e187 423 SUPERFAMILY SSF51735 166 318 1.09E-33 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c43620 5eab5eb44771ecac0740d97c87f0e187 423 SUPERFAMILY SSF69742 1 161 2.22E-42 T 12-10-2018 IPR036343 Glutamyl-tRNA reductase, N-terminal domain superfamily GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 VAPA_1c43620 5eab5eb44771ecac0740d97c87f0e187 423 PIRSF PIRSF000445 1 423 6.8E-142 T 12-10-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 VAPA_1c43620 5eab5eb44771ecac0740d97c87f0e187 423 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 175 309 8.2E-45 T 12-10-2018 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase VAPA_1c43620 5eab5eb44771ecac0740d97c87f0e187 423 ProSitePatterns PS00747 Glutamyl-tRNA reductase signature. 102 125 - T 12-10-2018 IPR018214 Glutamyl-tRNA reductase, conserved site GO:0008883|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 VAPA_1c43620 5eab5eb44771ecac0740d97c87f0e187 423 Pfam PF05201 Glutamyl-tRNAGlu reductase, N-terminal domain 6 159 4.8E-45 T 12-10-2018 IPR015895 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, N-terminal GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 VAPA_1c43620 5eab5eb44771ecac0740d97c87f0e187 423 SUPERFAMILY SSF69075 320 418 3.14E-20 T 12-10-2018 IPR036453 Glutamyl tRNA-reductase dimerization domain superfamily GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 VAPA_1c43620 5eab5eb44771ecac0740d97c87f0e187 423 Gene3D G3DSA:3.30.460.30 1 161 8.0E-51 T 12-10-2018 IPR036343 Glutamyl-tRNA reductase, N-terminal domain superfamily GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 VAPA_1c43620 5eab5eb44771ecac0740d97c87f0e187 423 Gene3D G3DSA:3.40.50.720 164 316 5.4E-43 T 12-10-2018 VAPA_1c43620 5eab5eb44771ecac0740d97c87f0e187 423 TIGRFAM TIGR01035 hemA: glutamyl-tRNA reductase 4 418 2.2E-119 T 12-10-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 VAPA_1c43620 5eab5eb44771ecac0740d97c87f0e187 423 Pfam PF00745 Glutamyl-tRNAGlu reductase, dimerisation domain 323 418 3.7E-27 T 12-10-2018 IPR015896 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, dimerisation domain GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 VAPA_1c44010 2383cb3cec77287b3dbdb7926e70b582 101 Pfam PF00699 Urease beta subunit 3 100 4.6E-43 T 12-10-2018 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 VAPA_1c44010 2383cb3cec77287b3dbdb7926e70b582 101 Gene3D G3DSA:2.10.150.10 1 101 3.4E-45 T 12-10-2018 IPR036461 Urease, beta subunit superfamily KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 VAPA_1c44010 2383cb3cec77287b3dbdb7926e70b582 101 SUPERFAMILY SSF51278 1 101 7.46E-46 T 12-10-2018 IPR036461 Urease, beta subunit superfamily KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 VAPA_1c44010 2383cb3cec77287b3dbdb7926e70b582 101 TIGRFAM TIGR00192 urease_beta: urease, beta subunit 1 101 3.8E-44 T 12-10-2018 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 VAPA_1c44010 2383cb3cec77287b3dbdb7926e70b582 101 Hamap MF_01954 Urease subunit beta [ureB]. 1 101 30.332 T 12-10-2018 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 VAPA_2c03790 0c915e76f7b5caef04f91256f55c97a7 451 Gene3D G3DSA:3.30.565.10 300 449 8.7E-24 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_2c03790 0c915e76f7b5caef04f91256f55c97a7 451 Gene3D G3DSA:1.10.287.130 181 295 1.3E-21 T 12-10-2018 VAPA_2c03790 0c915e76f7b5caef04f91256f55c97a7 451 SUPERFAMILY SSF47384 214 295 2.35E-14 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 VAPA_2c03790 0c915e76f7b5caef04f91256f55c97a7 451 SMART SM00388 230 295 9.5E-13 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 VAPA_2c03790 0c915e76f7b5caef04f91256f55c97a7 451 SUPERFAMILY SSF55874 285 444 8.91E-27 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_2c03790 0c915e76f7b5caef04f91256f55c97a7 451 Pfam PF08521 Two-component sensor kinase N-terminal 17 150 3.4E-11 T 12-10-2018 IPR013727 Two-component sensor kinase, N-terminal VAPA_2c03790 0c915e76f7b5caef04f91256f55c97a7 451 Pfam PF00512 His Kinase A (phospho-acceptor) domain 232 295 2.9E-11 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 VAPA_2c03790 0c915e76f7b5caef04f91256f55c97a7 451 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 344 448 9.8E-15 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase VAPA_2c03790 0c915e76f7b5caef04f91256f55c97a7 451 SMART SM00387 344 450 1.5E-25 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase VAPA_1c29540 05d305f1563fbb2a0328754dc4ca766b 441 ProSitePatterns PS00571 Amidases signature. 143 174 - T 12-10-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 VAPA_1c29540 05d305f1563fbb2a0328754dc4ca766b 441 Gene3D G3DSA:3.90.1300.10 11 439 2.2E-103 T 12-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 VAPA_1c29540 05d305f1563fbb2a0328754dc4ca766b 441 SUPERFAMILY SSF75304 32 439 1.57E-99 T 12-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 VAPA_1c29540 05d305f1563fbb2a0328754dc4ca766b 441 Pfam PF01425 Amidase 44 428 1.7E-71 T 12-10-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 VAPA_1c02250 fca1b60c0b26b7029c550ca7f2a56d5a 1252 SUPERFAMILY SSF56003 46 235 1.69E-32 T 12-10-2018 IPR037165 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain superfamily GO:0016491|GO:0055114 VAPA_1c02250 fca1b60c0b26b7029c550ca7f2a56d5a 1252 Gene3D G3DSA:1.10.760.10 823 971 6.8E-8 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 VAPA_1c02250 fca1b60c0b26b7029c550ca7f2a56d5a 1252 SUPERFAMILY SSF54665 210 295 3.35E-9 T 12-10-2018 IPR036856 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead superfamily VAPA_1c02250 fca1b60c0b26b7029c550ca7f2a56d5a 1252 SUPERFAMILY SSF56003 315 773 2.68E-107 T 12-10-2018 IPR037165 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain superfamily GO:0016491|GO:0055114 VAPA_1c02250 fca1b60c0b26b7029c550ca7f2a56d5a 1252 Gene3D G3DSA:3.30.365.10 47 180 4.1E-31 T 12-10-2018 VAPA_1c02250 fca1b60c0b26b7029c550ca7f2a56d5a 1252 SUPERFAMILY SSF46626 1005 1112 2.56E-14 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 VAPA_1c02250 fca1b60c0b26b7029c550ca7f2a56d5a 1252 Gene3D G3DSA:3.90.1170.50 181 268 1.4E-8 T 12-10-2018 VAPA_1c02250 fca1b60c0b26b7029c550ca7f2a56d5a 1252 Gene3D G3DSA:3.30.365.10 269 586 2.8E-48 T 12-10-2018 VAPA_1c02250 fca1b60c0b26b7029c550ca7f2a56d5a 1252 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 1143 1222 5.5E-9 T 12-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 VAPA_1c02250 fca1b60c0b26b7029c550ca7f2a56d5a 1252 Gene3D G3DSA:3.30.365.10 604 775 4.4E-44 T 12-10-2018 VAPA_1c02250 fca1b60c0b26b7029c550ca7f2a56d5a 1252 Gene3D G3DSA:1.10.760.10 997 1113 1.6E-8 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 VAPA_1c02250 fca1b60c0b26b7029c550ca7f2a56d5a 1252 Gene3D G3DSA:1.10.760.10 1122 1251 9.4E-16 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 VAPA_1c02250 fca1b60c0b26b7029c550ca7f2a56d5a 1252 SUPERFAMILY SSF46626 856 985 3.43E-23 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 VAPA_1c02250 fca1b60c0b26b7029c550ca7f2a56d5a 1252 Pfam PF00034 Cytochrome c 863 962 1.8E-4 T 12-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 VAPA_1c02250 fca1b60c0b26b7029c550ca7f2a56d5a 1252 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 318 565 1.1E-32 T 12-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 VAPA_1c02250 fca1b60c0b26b7029c550ca7f2a56d5a 1252 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 47 172 4.5E-19 T 12-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 VAPA_1c02250 fca1b60c0b26b7029c550ca7f2a56d5a 1252 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 616 683 9.2E-14 T 12-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 VAPA_1c02250 fca1b60c0b26b7029c550ca7f2a56d5a 1252 SUPERFAMILY SSF46626 1142 1242 8.56E-15 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 VAPA_1c02250 fca1b60c0b26b7029c550ca7f2a56d5a 1252 SMART SM01008 209 295 3.5E-19 T 12-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead VAPA_1c42060 597a236a0067ba2e9d97e6f39d53421a 298 Gene3D G3DSA:3.40.190.10 162 260 1.4E-66 T 12-10-2018 VAPA_1c42060 597a236a0067ba2e9d97e6f39d53421a 298 SUPERFAMILY SSF46785 5 85 7.96E-21 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c42060 597a236a0067ba2e9d97e6f39d53421a 298 Pfam PF03466 LysR substrate binding domain 88 288 4.3E-51 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_1c42060 597a236a0067ba2e9d97e6f39d53421a 298 Gene3D G3DSA:1.10.10.10 2 86 9.0E-24 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c42060 597a236a0067ba2e9d97e6f39d53421a 298 SUPERFAMILY SSF53850 90 289 2.02E-49 T 12-10-2018 VAPA_1c42060 597a236a0067ba2e9d97e6f39d53421a 298 Gene3D G3DSA:3.40.190.10 91 286 1.4E-66 T 12-10-2018 VAPA_1c42060 597a236a0067ba2e9d97e6f39d53421a 298 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 62 9.6E-17 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c20890 d2b0ef18e70e1a45938f46e6600bb1e6 433 Pfam PF00293 NUDIX domain 6 98 7.4E-7 T 12-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 VAPA_1c20890 d2b0ef18e70e1a45938f46e6600bb1e6 433 SUPERFAMILY SSF56281 295 414 1.74E-9 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like VAPA_1c20890 d2b0ef18e70e1a45938f46e6600bb1e6 433 SUPERFAMILY SSF55811 3 196 1.08E-14 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 VAPA_1c20890 d2b0ef18e70e1a45938f46e6600bb1e6 433 Gene3D G3DSA:3.90.79.10 2 238 2.9E-56 T 12-10-2018 VAPA_2c09600 f0757303e7887dda1814cba01f59b218 242 SMART SM00866 96 235 5.1E-20 T 12-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 VAPA_2c09600 f0757303e7887dda1814cba01f59b218 242 Gene3D G3DSA:1.10.10.10 2 75 7.8E-23 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_2c09600 f0757303e7887dda1814cba01f59b218 242 SUPERFAMILY SSF64288 62 240 1.0E-32 T 12-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily VAPA_2c09600 f0757303e7887dda1814cba01f59b218 242 Pfam PF07702 UTRA domain 107 235 1.7E-23 T 12-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 VAPA_2c09600 f0757303e7887dda1814cba01f59b218 242 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 48 64 1.0E-10 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_2c09600 f0757303e7887dda1814cba01f59b218 242 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 34 48 1.0E-10 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_2c09600 f0757303e7887dda1814cba01f59b218 242 Pfam PF00392 Bacterial regulatory proteins, gntR family 13 73 1.1E-20 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_2c09600 f0757303e7887dda1814cba01f59b218 242 SUPERFAMILY SSF46785 4 76 7.16E-21 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_2c09600 f0757303e7887dda1814cba01f59b218 242 Gene3D G3DSA:3.40.1410.10 84 241 6.2E-28 T 12-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily VAPA_2c09600 f0757303e7887dda1814cba01f59b218 242 SMART SM00345 15 74 1.1E-21 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_1c17170 241a82e0fc9fb328081ede6117a88b91 242 Hamap MF_00472 Ubiquinone biosynthesis O-methyltransferase [ubiG]. 11 235 36.296 T 12-10-2018 IPR010233 Ubiquinone biosynthesis O-methyltransferase GO:0006744|GO:0008425 KEGG: 00130+2.1.1.222+2.1.1.64|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-5870|MetaCyc: PWY-5871|MetaCyc: PWY-5872|MetaCyc: PWY-5873|MetaCyc: PWY-6708|MetaCyc: PWY-7230|MetaCyc: PWY-7233|Reactome: R-HSA-2142789 VAPA_1c17170 241a82e0fc9fb328081ede6117a88b91 242 TIGRFAM TIGR01983 UbiG: 3-demethylubiquinone-9 3-O-methyltransferase 11 229 6.3E-82 T 12-10-2018 IPR010233 Ubiquinone biosynthesis O-methyltransferase GO:0006744|GO:0008425 KEGG: 00130+2.1.1.222+2.1.1.64|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-5870|MetaCyc: PWY-5871|MetaCyc: PWY-5872|MetaCyc: PWY-5873|MetaCyc: PWY-6708|MetaCyc: PWY-7230|MetaCyc: PWY-7233|Reactome: R-HSA-2142789 VAPA_1c17170 241a82e0fc9fb328081ede6117a88b91 242 SUPERFAMILY SSF53335 13 235 3.38E-47 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase VAPA_1c17170 241a82e0fc9fb328081ede6117a88b91 242 Gene3D G3DSA:3.40.50.150 11 234 1.3E-70 T 12-10-2018 VAPA_1c17170 241a82e0fc9fb328081ede6117a88b91 242 Pfam PF13489 Methyltransferase domain 50 204 6.4E-27 T 12-10-2018 VAPA_1c03530 c64d213214809cdea15628cce5dc4705 573 Gene3D G3DSA:3.30.70.2450 203 320 8.8E-85 T 12-10-2018 VAPA_1c03530 c64d213214809cdea15628cce5dc4705 573 SUPERFAMILY SSF51905 25 430 1.63E-62 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c03530 c64d213214809cdea15628cce5dc4705 573 Gene3D G3DSA:3.40.30.120 435 573 3.7E-12 T 12-10-2018 VAPA_1c03530 c64d213214809cdea15628cce5dc4705 573 Pfam PF01494 FAD binding domain 26 394 6.9E-62 T 12-10-2018 IPR002938 FAD-binding domain GO:0071949 VAPA_1c03530 c64d213214809cdea15628cce5dc4705 573 Gene3D G3DSA:3.50.50.60 27 392 8.8E-85 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c03530 c64d213214809cdea15628cce5dc4705 573 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 174 189 2.6E-33 T 12-10-2018 VAPA_1c03530 c64d213214809cdea15628cce5dc4705 573 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 26 48 2.6E-33 T 12-10-2018 VAPA_1c03530 c64d213214809cdea15628cce5dc4705 573 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 346 362 2.6E-33 T 12-10-2018 VAPA_1c03530 c64d213214809cdea15628cce5dc4705 573 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 331 346 2.6E-33 T 12-10-2018 VAPA_1c03530 c64d213214809cdea15628cce5dc4705 573 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 364 382 2.6E-33 T 12-10-2018 VAPA_1c07990 5e1f71fad8ab4da5836d12cd16874e5b 539 Gene3D G3DSA:2.40.240.50 229 333 3.8E-22 T 12-10-2018 VAPA_1c07990 5e1f71fad8ab4da5836d12cd16874e5b 539 SMART SM00925 171 405 1.3E-16 T 12-10-2018 IPR005300 Lytic transglycosylase MltA, domain B GO:0004553 VAPA_1c07990 5e1f71fad8ab4da5836d12cd16874e5b 539 SUPERFAMILY SSF50685 396 506 1.22E-41 T 12-10-2018 IPR036908 RlpA-like domain superfamily VAPA_1c07990 5e1f71fad8ab4da5836d12cd16874e5b 539 Gene3D G3DSA:2.40.240.50 397 407 3.2E-40 T 12-10-2018 VAPA_1c07990 5e1f71fad8ab4da5836d12cd16874e5b 539 Gene3D G3DSA:2.40.40.10 65 182 6.0E-26 T 12-10-2018 IPR036908 RlpA-like domain superfamily VAPA_1c07990 5e1f71fad8ab4da5836d12cd16874e5b 539 Pfam PF06725 3D domain 426 499 7.0E-21 T 12-10-2018 IPR010611 3D domain GO:0004553|GO:0009254|GO:0019867 VAPA_1c07990 5e1f71fad8ab4da5836d12cd16874e5b 539 Pfam PF03562 MltA specific insert domain 96 321 1.6E-46 T 12-10-2018 IPR005300 Lytic transglycosylase MltA, domain B GO:0004553 VAPA_1c07990 5e1f71fad8ab4da5836d12cd16874e5b 539 Gene3D G3DSA:2.40.40.10 413 502 3.2E-40 T 12-10-2018 IPR036908 RlpA-like domain superfamily VAPA_1c07990 5e1f71fad8ab4da5836d12cd16874e5b 539 SUPERFAMILY SSF50685 83 321 1.6E-50 T 12-10-2018 IPR036908 RlpA-like domain superfamily VAPA_1c41310 bc6d05b485c94291f24d451c4901e682 717 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 66 717 7.5E-93 T 12-10-2018 IPR010105 TonB-dependent siderophore receptor GO:0005506|GO:0015891|GO:0038023 VAPA_1c41310 bc6d05b485c94291f24d451c4901e682 717 Gene3D G3DSA:2.40.170.20 174 717 2.5E-119 T 12-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily VAPA_1c41310 bc6d05b485c94291f24d451c4901e682 717 Pfam PF00593 TonB dependent receptor 241 715 2.0E-57 T 12-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel VAPA_1c41310 bc6d05b485c94291f24d451c4901e682 717 Pfam PF07715 TonB-dependent Receptor Plug Domain 64 159 2.0E-23 T 12-10-2018 IPR012910 TonB-dependent receptor, plug domain VAPA_1c41310 bc6d05b485c94291f24d451c4901e682 717 SUPERFAMILY SSF56935 27 717 5.95E-143 T 12-10-2018 VAPA_1c41310 bc6d05b485c94291f24d451c4901e682 717 ProSitePatterns PS01156 TonB-dependent receptor proteins signature 2. 700 717 - T 12-10-2018 IPR010917 TonB-dependent receptor, conserved site VAPA_1c41310 bc6d05b485c94291f24d451c4901e682 717 Gene3D G3DSA:2.170.130.10 49 169 4.0E-39 T 12-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily VAPA_2c04080 c2bee7198c14d95ad982dc8c3301288e 223 Pfam PF00072 Response regulator receiver domain 3 112 5.0E-22 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_2c04080 c2bee7198c14d95ad982dc8c3301288e 223 Pfam PF00486 Transcriptional regulatory protein, C terminal 147 216 3.0E-23 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 VAPA_2c04080 c2bee7198c14d95ad982dc8c3301288e 223 Gene3D G3DSA:1.10.10.10 122 221 6.7E-30 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_2c04080 c2bee7198c14d95ad982dc8c3301288e 223 Gene3D G3DSA:3.40.50.2300 1 121 5.9E-35 T 12-10-2018 VAPA_2c04080 c2bee7198c14d95ad982dc8c3301288e 223 SMART SM00448 1 112 1.7E-33 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_2c04080 c2bee7198c14d95ad982dc8c3301288e 223 SMART SM00862 145 216 6.8E-28 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 VAPA_2c04080 c2bee7198c14d95ad982dc8c3301288e 223 SUPERFAMILY SSF52172 1 177 5.15E-36 T 12-10-2018 IPR011006 CheY-like superfamily VAPA_1c49910 58426d9c6aa6b008f7cb309a8ca30784 243 SUPERFAMILY SSF47616 110 235 1.12E-20 T 12-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily VAPA_1c49910 58426d9c6aa6b008f7cb309a8ca30784 243 Pfam PF14497 Glutathione S-transferase, C-terminal domain 115 223 1.3E-26 T 12-10-2018 IPR004046 Glutathione S-transferase, C-terminal VAPA_1c49910 58426d9c6aa6b008f7cb309a8ca30784 243 Gene3D G3DSA:3.40.30.10 4 242 2.2E-85 T 12-10-2018 VAPA_1c49910 58426d9c6aa6b008f7cb309a8ca30784 243 Gene3D G3DSA:1.20.1050.10 92 213 2.2E-85 T 12-10-2018 VAPA_1c49910 58426d9c6aa6b008f7cb309a8ca30784 243 SUPERFAMILY SSF52833 1 88 8.15E-17 T 12-10-2018 IPR036249 Thioredoxin-like superfamily VAPA_1c22310 c4abba91ef70f90dd462d80782b571ef 467 SUPERFAMILY SSF53850 109 330 2.61E-38 T 12-10-2018 VAPA_1c22310 c4abba91ef70f90dd462d80782b571ef 467 Gene3D G3DSA:3.40.190.10 112 448 6.2E-112 T 12-10-2018 VAPA_1c22310 c4abba91ef70f90dd462d80782b571ef 467 Pfam PF13379 NMT1-like family 106 343 1.7E-78 T 12-10-2018 VAPA_1c22310 c4abba91ef70f90dd462d80782b571ef 467 Gene3D G3DSA:3.40.190.10 198 453 6.2E-112 T 12-10-2018 VAPA_1c23850 3f5f3bcceb229c940001807ac88f14bb 226 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 45 207 5.3E-23 T 12-10-2018 IPR013830 SGNH hydrolase-type esterase domain VAPA_1c23850 3f5f3bcceb229c940001807ac88f14bb 226 SUPERFAMILY SSF52266 41 223 6.41E-46 T 12-10-2018 VAPA_1c23850 3f5f3bcceb229c940001807ac88f14bb 226 Gene3D G3DSA:3.40.50.1110 42 226 1.2E-65 T 12-10-2018 IPR036514 SGNH hydrolase superfamily VAPA_1c43100 0f62219cbc73ac2e268144b6f49a4852 273 PIRSF PIRSF000410 2 270 2.7E-95 T 12-10-2018 IPR026024 Chemotaxis protein methyltransferase CheR VAPA_1c43100 0f62219cbc73ac2e268144b6f49a4852 273 Gene3D G3DSA:3.40.50.150 76 269 4.5E-67 T 12-10-2018 VAPA_1c43100 0f62219cbc73ac2e268144b6f49a4852 273 SUPERFAMILY SSF47757 3 76 2.88E-22 T 12-10-2018 VAPA_1c43100 0f62219cbc73ac2e268144b6f49a4852 273 Gene3D G3DSA:1.10.155.10 1 75 5.2E-28 T 12-10-2018 IPR036804 Chemotaxis receptor methyltransferase CheR, N-terminal domain superfamily VAPA_1c43100 0f62219cbc73ac2e268144b6f49a4852 273 PRINTS PR00996 Glutamate methyltransferase family signature 209 223 1.7E-43 T 12-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 VAPA_1c43100 0f62219cbc73ac2e268144b6f49a4852 273 PRINTS PR00996 Glutamate methyltransferase family signature 137 153 1.7E-43 T 12-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 VAPA_1c43100 0f62219cbc73ac2e268144b6f49a4852 273 PRINTS PR00996 Glutamate methyltransferase family signature 70 82 1.7E-43 T 12-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 VAPA_1c43100 0f62219cbc73ac2e268144b6f49a4852 273 PRINTS PR00996 Glutamate methyltransferase family signature 31 44 1.7E-43 T 12-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 VAPA_1c43100 0f62219cbc73ac2e268144b6f49a4852 273 PRINTS PR00996 Glutamate methyltransferase family signature 228 251 1.7E-43 T 12-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 VAPA_1c43100 0f62219cbc73ac2e268144b6f49a4852 273 PRINTS PR00996 Glutamate methyltransferase family signature 103 123 1.7E-43 T 12-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 VAPA_1c43100 0f62219cbc73ac2e268144b6f49a4852 273 Pfam PF03705 CheR methyltransferase, all-alpha domain 11 61 7.9E-18 T 12-10-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal VAPA_1c43100 0f62219cbc73ac2e268144b6f49a4852 273 Pfam PF01739 CheR methyltransferase, SAM binding domain 77 266 9.5E-57 T 12-10-2018 IPR022642 MCP methyltransferase, CheR-type, SAM-binding domain, C-terminal VAPA_1c43100 0f62219cbc73ac2e268144b6f49a4852 273 SMART SM00138 9 269 3.6E-103 T 12-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 VAPA_1c43100 0f62219cbc73ac2e268144b6f49a4852 273 SUPERFAMILY SSF53335 77 266 5.06E-55 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase VAPA_1c16860 aabd4a9ea30227d02fadd883019847e2 125 Gene3D G3DSA:3.10.450.50 5 121 1.4E-37 T 12-10-2018 VAPA_1c16860 aabd4a9ea30227d02fadd883019847e2 125 SUPERFAMILY SSF54427 7 119 3.73E-34 T 12-10-2018 IPR032710 NTF2-like domain superfamily VAPA_1c16860 aabd4a9ea30227d02fadd883019847e2 125 Pfam PF12680 SnoaL-like domain 12 112 3.7E-14 T 12-10-2018 IPR037401 SnoaL-like domain VAPA_1c07960 7779501cabd792e13230e36c7793de5d 275 Pfam PF02633 Creatinine amidohydrolase 14 255 3.6E-60 T 12-10-2018 IPR003785 Creatininase/formamide hydrolase KEGG: 00740+3.5.1.102|MetaCyc: PWY-6167 VAPA_1c07960 7779501cabd792e13230e36c7793de5d 275 SUPERFAMILY SSF102215 10 261 2.62E-62 T 12-10-2018 IPR024087 Creatininase-like superfamily KEGG: 00740+3.5.1.102|MetaCyc: PWY-6167 VAPA_1c07960 7779501cabd792e13230e36c7793de5d 275 Gene3D G3DSA:3.40.50.10310 6 263 1.2E-63 T 12-10-2018 IPR024087 Creatininase-like superfamily KEGG: 00740+3.5.1.102|MetaCyc: PWY-6167 VAPA_1c41670 3eb386714e11eca1e38a735c1eabd278 346 Gene3D G3DSA:1.20.58.340 290 346 1.0E-15 T 12-10-2018 VAPA_1c41670 3eb386714e11eca1e38a735c1eabd278 346 SUPERFAMILY SSF143865 17 280 3.14E-39 T 12-10-2018 VAPA_1c41670 3eb386714e11eca1e38a735c1eabd278 346 Gene3D G3DSA:1.20.58.340 159 282 4.4E-18 T 12-10-2018 VAPA_1c41670 3eb386714e11eca1e38a735c1eabd278 346 Gene3D G3DSA:3.30.460.20 10 157 1.6E-32 T 12-10-2018 VAPA_1c41670 3eb386714e11eca1e38a735c1eabd278 346 SUPERFAMILY SSF144083 283 345 1.26E-15 T 12-10-2018 VAPA_1c41670 3eb386714e11eca1e38a735c1eabd278 346 Pfam PF01544 CorA-like Mg2+ transporter protein 58 339 1.0E-53 T 12-10-2018 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 VAPA_1c04380 ecce60cb320791617040c105dc7d217c 485 Gene3D G3DSA:3.30.750.24 387 482 9.6E-24 T 12-10-2018 IPR036513 STAS domain superfamily VAPA_1c04380 ecce60cb320791617040c105dc7d217c 485 SUPERFAMILY SSF52091 399 481 2.55E-11 T 12-10-2018 IPR036513 STAS domain superfamily VAPA_1c04380 ecce60cb320791617040c105dc7d217c 485 Pfam PF01740 STAS domain 399 477 1.3E-7 T 12-10-2018 IPR002645 STAS domain VAPA_1c04380 ecce60cb320791617040c105dc7d217c 485 Pfam PF00916 Sulfate permease family 146 357 1.5E-29 T 12-10-2018 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 VAPA_1c06970 ecb6e874f3e76d616670d7a0d7780f69 582 Gene3D G3DSA:3.50.50.60 73 577 8.0E-158 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c06970 ecb6e874f3e76d616670d7a0d7780f69 582 Pfam PF00732 GMC oxidoreductase 73 368 6.9E-68 T 12-10-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 VAPA_1c06970 ecb6e874f3e76d616670d7a0d7780f69 582 SUPERFAMILY SSF51905 73 578 1.3E-67 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c06970 ecb6e874f3e76d616670d7a0d7780f69 582 ProSitePatterns PS00623 GMC oxidoreductases signature 1. 149 172 - T 12-10-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 VAPA_1c06970 ecb6e874f3e76d616670d7a0d7780f69 582 Gene3D G3DSA:4.10.450.10 106 268 8.0E-158 T 12-10-2018 IPR027424 Glucose Oxidase, domain 2 KEGG: 00260+1.2.1.8+1.1.99.1|MetaCyc: PWY-3722|MetaCyc: PWY-7494|Reactome: R-HSA-6798163 VAPA_1c06970 ecb6e874f3e76d616670d7a0d7780f69 582 Gene3D G3DSA:3.30.410.40 220 521 8.0E-158 T 12-10-2018 VAPA_1c06970 ecb6e874f3e76d616670d7a0d7780f69 582 PIRSF PIRSF000137 393 581 2.5E-47 T 12-10-2018 IPR012132 Glucose-methanol-choline oxidoreductase GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 VAPA_1c06970 ecb6e874f3e76d616670d7a0d7780f69 582 PIRSF PIRSF000137 47 417 1.3E-78 T 12-10-2018 IPR012132 Glucose-methanol-choline oxidoreductase GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 VAPA_1c06970 ecb6e874f3e76d616670d7a0d7780f69 582 Gene3D G3DSA:1.10.1220.110 164 219 8.0E-158 T 12-10-2018 VAPA_1c06970 ecb6e874f3e76d616670d7a0d7780f69 582 Pfam PF05199 GMC oxidoreductase 439 574 1.5E-38 T 12-10-2018 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 VAPA_1c06970 ecb6e874f3e76d616670d7a0d7780f69 582 SUPERFAMILY SSF54373 363 524 2.16E-33 T 12-10-2018 VAPA_1c06970 ecb6e874f3e76d616670d7a0d7780f69 582 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 29 51 9.9E-4 T 12-10-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal VAPA_1c19660 2b403706f9456198d76e68b3dff8805e 179 TIGRFAM TIGR00168 infC: translation initiation factor IF-3 2 158 4.5E-60 T 12-10-2018 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 VAPA_1c19660 2b403706f9456198d76e68b3dff8805e 179 SUPERFAMILY SSF54364 2 66 1.03E-21 T 12-10-2018 IPR036787 Translation initiation factor 3 (IF-3), N-terminal domain superfamily GO:0003743|GO:0006413 Reactome: R-HSA-5368286 VAPA_1c19660 2b403706f9456198d76e68b3dff8805e 179 Gene3D G3DSA:3.30.110.10 65 160 8.9E-37 T 12-10-2018 IPR036788 Translation initiation factor 3 (IF-3), C-terminal domain superfamily GO:0006413 Reactome: R-HSA-5368286 VAPA_1c19660 2b403706f9456198d76e68b3dff8805e 179 Pfam PF00707 Translation initiation factor IF-3, C-terminal domain 72 156 8.5E-38 T 12-10-2018 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 VAPA_1c19660 2b403706f9456198d76e68b3dff8805e 179 Gene3D G3DSA:3.10.20.80 1 64 3.6E-24 T 12-10-2018 IPR036787 Translation initiation factor 3 (IF-3), N-terminal domain superfamily GO:0003743|GO:0006413 Reactome: R-HSA-5368286 VAPA_1c19660 2b403706f9456198d76e68b3dff8805e 179 Hamap MF_00080 Translation initiation factor IF-3 [infC]. 1 159 26.416 T 12-10-2018 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 VAPA_1c19660 2b403706f9456198d76e68b3dff8805e 179 SUPERFAMILY SSF55200 72 157 2.22E-33 T 12-10-2018 IPR036788 Translation initiation factor 3 (IF-3), C-terminal domain superfamily GO:0006413 Reactome: R-HSA-5368286 VAPA_1c19660 2b403706f9456198d76e68b3dff8805e 179 Pfam PF05198 Translation initiation factor IF-3, N-terminal domain 2 65 3.4E-23 T 12-10-2018 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 VAPA_1c48910 3a94d0dc9f1cd04c099f68531aa8333d 376 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 120 215 6.3E-25 T 12-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 VAPA_1c48910 3a94d0dc9f1cd04c099f68531aa8333d 376 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 227 375 6.5E-49 T 12-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 VAPA_1c48910 3a94d0dc9f1cd04c099f68531aa8333d 376 SUPERFAMILY SSF56645 2 240 1.57E-79 T 12-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 VAPA_1c48910 3a94d0dc9f1cd04c099f68531aa8333d 376 Gene3D G3DSA:2.40.110.10 119 231 3.4E-43 T 12-10-2018 VAPA_1c48910 3a94d0dc9f1cd04c099f68531aa8333d 376 PIRSF PIRSF016578 4 191 1.6E-8 T 12-10-2018 VAPA_1c48910 3a94d0dc9f1cd04c099f68531aa8333d 376 PIRSF PIRSF016578 219 365 1.5E-12 T 12-10-2018 VAPA_1c48910 3a94d0dc9f1cd04c099f68531aa8333d 376 Gene3D G3DSA:1.10.540.10 1 118 1.0E-37 T 12-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 VAPA_1c48910 3a94d0dc9f1cd04c099f68531aa8333d 376 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 5 115 6.2E-33 T 12-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 VAPA_1c48910 3a94d0dc9f1cd04c099f68531aa8333d 376 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 122 134 - T 12-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 VAPA_1c48910 3a94d0dc9f1cd04c099f68531aa8333d 376 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 334 353 - T 12-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 VAPA_1c48910 3a94d0dc9f1cd04c099f68531aa8333d 376 SUPERFAMILY SSF47203 226 375 7.41E-55 T 12-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 VAPA_1c48910 3a94d0dc9f1cd04c099f68531aa8333d 376 Gene3D G3DSA:1.20.140.10 232 376 8.0E-54 T 12-10-2018 VAPA_1c26360 f8fcf030ecfc9490248bcf0a84208adb 154 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 20 131 5.6E-21 T 12-10-2018 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-77289 VAPA_1c26360 f8fcf030ecfc9490248bcf0a84208adb 154 SUPERFAMILY SSF54637 14 137 1.51E-32 T 12-10-2018 IPR029069 HotDog domain superfamily VAPA_1c26360 f8fcf030ecfc9490248bcf0a84208adb 154 Pfam PF03061 Thioesterase superfamily 52 125 5.0E-11 T 12-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 VAPA_1c26360 f8fcf030ecfc9490248bcf0a84208adb 154 Gene3D G3DSA:3.10.129.10 9 140 3.2E-43 T 12-10-2018 VAPA_1c05370 599cf6455f3f974acc2124c4a38d3b54 321 SUPERFAMILY SSF46785 3 111 2.56E-17 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c05370 599cf6455f3f974acc2124c4a38d3b54 321 SUPERFAMILY SSF53850 91 313 5.79E-38 T 12-10-2018 VAPA_1c05370 599cf6455f3f974acc2124c4a38d3b54 321 Gene3D G3DSA:3.40.190.290 91 311 2.2E-58 T 12-10-2018 VAPA_1c05370 599cf6455f3f974acc2124c4a38d3b54 321 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 3.5E-14 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c05370 599cf6455f3f974acc2124c4a38d3b54 321 Gene3D G3DSA:1.10.10.10 3 87 4.3E-22 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c05370 599cf6455f3f974acc2124c4a38d3b54 321 Pfam PF03466 LysR substrate binding domain 90 310 2.8E-34 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_1c14660 948114d492ac6e9472f373e5aaada2c0 947 SUPERFAMILY SSF51621 22 947 3.3E-290 T 12-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 VAPA_1c14660 948114d492ac6e9472f373e5aaada2c0 947 ProSitePatterns PS00781 Phosphoenolpyruvate carboxylase active site 1. 150 161 - T 12-10-2018 IPR018129 Phosphoenolpyruvate carboxylase, Lys active site KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 VAPA_1c14660 948114d492ac6e9472f373e5aaada2c0 947 Hamap MF_00595 Phosphoenolpyruvate carboxylase [ppc]. 13 947 19.126 T 12-10-2018 IPR022805 Phosphoenolpyruvate carboxylase, bacterial/plant-type GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 VAPA_1c14660 948114d492ac6e9472f373e5aaada2c0 947 ProSitePatterns PS00393 Phosphoenolpyruvate carboxylase active site 2. 590 602 - T 12-10-2018 IPR033129 Phosphoenolpyruvate carboxylase, His active site KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 VAPA_1c14660 948114d492ac6e9472f373e5aaada2c0 947 Pfam PF00311 Phosphoenolpyruvate carboxylase 147 947 1.4E-278 T 12-10-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 VAPA_1c14660 948114d492ac6e9472f373e5aaada2c0 947 Gene3D G3DSA:1.20.1440.90 300 425 5.7E-11 T 12-10-2018 VAPA_1c14660 948114d492ac6e9472f373e5aaada2c0 947 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 149 162 5.1E-43 T 12-10-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 VAPA_1c14660 948114d492ac6e9472f373e5aaada2c0 947 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 271 286 5.1E-43 T 12-10-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 VAPA_1c14660 948114d492ac6e9472f373e5aaada2c0 947 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 636 665 5.1E-43 T 12-10-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 VAPA_1c14660 948114d492ac6e9472f373e5aaada2c0 947 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 769 795 5.1E-43 T 12-10-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 VAPA_1c14660 948114d492ac6e9472f373e5aaada2c0 947 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 422 442 5.1E-43 T 12-10-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 VAPA_1c38960 c7bd38275433e1725d5e16aec33d3df6 446 TIGRFAM TIGR00032 argG: argininosuccinate synthase 13 419 7.1E-155 T 12-10-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 VAPA_1c38960 c7bd38275433e1725d5e16aec33d3df6 446 Pfam PF00764 Arginosuccinate synthase 16 407 4.6E-58 T 12-10-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 VAPA_1c38960 c7bd38275433e1725d5e16aec33d3df6 446 Gene3D G3DSA:1.10.287.400 377 440 2.9E-31 T 12-10-2018 IPR024073 Argininosuccinate synthetase mutimerisation domain, C-terminal tail GO:0042803 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400 VAPA_1c38960 c7bd38275433e1725d5e16aec33d3df6 446 ProSitePatterns PS00565 Argininosuccinate synthase signature 2. 129 140 - T 12-10-2018 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 VAPA_1c38960 c7bd38275433e1725d5e16aec33d3df6 446 Gene3D G3DSA:3.40.50.620 14 191 4.9E-117 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold VAPA_1c38960 c7bd38275433e1725d5e16aec33d3df6 446 ProSitePatterns PS00564 Argininosuccinate synthase signature 1. 17 25 - T 12-10-2018 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 VAPA_1c38960 c7bd38275433e1725d5e16aec33d3df6 446 SUPERFAMILY SSF52402 4 185 1.96E-31 T 12-10-2018 VAPA_1c38960 c7bd38275433e1725d5e16aec33d3df6 446 Gene3D G3DSA:3.90.1260.10 74 367 4.9E-117 T 12-10-2018 IPR024074 Argininosuccinate synthetase, catalytic/multimerisation domain body GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 VAPA_1c38960 c7bd38275433e1725d5e16aec33d3df6 446 SUPERFAMILY SSF69864 190 444 1.83E-79 T 12-10-2018 VAPA_1c38960 c7bd38275433e1725d5e16aec33d3df6 446 Hamap MF_00581 Argininosuccinate synthase [argG]. 1 446 68.566 T 12-10-2018 IPR023437 Argininosuccinate synthase, type 2 subfamily GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400 VAPA_1c53760 7a61bab2943b398ff66d82bbf98b92e1 1298 Gene3D G3DSA:3.40.50.410 185 347 2.7E-5 T 12-10-2018 IPR036465 von Willebrand factor A-like domain superfamily VAPA_1c53760 7a61bab2943b398ff66d82bbf98b92e1 1298 SUPERFAMILY SSF50998 862 1258 8.63E-9 T 12-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily VAPA_1c53760 7a61bab2943b398ff66d82bbf98b92e1 1298 Pfam PF05567 Neisseria PilC beta-propeller domain 828 1137 3.2E-54 T 12-10-2018 IPR008707 PilC beta-propeller domain VAPA_1c12970 717896b719e7406d486b92cddaa0a1b9 364 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 117 136 9.7E-6 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 VAPA_1c12970 717896b719e7406d486b92cddaa0a1b9 364 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 154 165 9.7E-6 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 VAPA_1c12970 717896b719e7406d486b92cddaa0a1b9 364 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 142 151 9.7E-6 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 VAPA_1c12970 717896b719e7406d486b92cddaa0a1b9 364 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 56 63 9.7E-6 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 VAPA_1c12970 717896b719e7406d486b92cddaa0a1b9 364 ProSitePatterns PS00019 Actinin-type actin-binding domain signature 1. 77 86 - T 12-10-2018 IPR001589 Actinin-type actin-binding domain, conserved site VAPA_1c12970 717896b719e7406d486b92cddaa0a1b9 364 Gene3D G3DSA:2.40.30.10 3 106 2.0E-23 T 12-10-2018 VAPA_1c12970 717896b719e7406d486b92cddaa0a1b9 364 Pfam PF00175 Oxidoreductase NAD-binding domain 119 226 3.1E-17 T 12-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 VAPA_1c12970 717896b719e7406d486b92cddaa0a1b9 364 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 280 352 2.9E-15 T 12-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 VAPA_1c12970 717896b719e7406d486b92cddaa0a1b9 364 SUPERFAMILY SSF54292 235 360 2.75E-27 T 12-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 VAPA_1c12970 717896b719e7406d486b92cddaa0a1b9 364 Gene3D G3DSA:3.10.20.30 261 364 1.1E-26 T 12-10-2018 IPR012675 Beta-grasp domain superfamily VAPA_1c12970 717896b719e7406d486b92cddaa0a1b9 364 Gene3D G3DSA:3.40.50.80 111 249 4.1E-30 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain VAPA_1c12970 717896b719e7406d486b92cddaa0a1b9 364 TIGRFAM TIGR02160 PA_CoA_Oxy5: phenylacetate-CoA oxygenase/reductase, PaaK subunit 5 362 9.9E-139 T 12-10-2018 IPR011884 Phenylacetate-CoA oxygenase/reductase, PaaK subunit GO:0010124 VAPA_1c12970 717896b719e7406d486b92cddaa0a1b9 364 SUPERFAMILY SSF52343 94 243 9.43E-35 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain VAPA_1c12970 717896b719e7406d486b92cddaa0a1b9 364 Pfam PF00970 Oxidoreductase FAD-binding domain 15 104 3.8E-14 T 12-10-2018 IPR008333 Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain Reactome: R-HSA-1237044 VAPA_1c12970 717896b719e7406d486b92cddaa0a1b9 364 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 310 318 - T 12-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 VAPA_1c12970 717896b719e7406d486b92cddaa0a1b9 364 PRINTS PR00406 Cytochrome B5 reductase signature 213 221 2.3E-9 T 12-10-2018 IPR001834 NADH:cytochrome b5 reductase (CBR) GO:0016491|GO:0055114 Reactome: R-HSA-1237044 VAPA_1c12970 717896b719e7406d486b92cddaa0a1b9 364 PRINTS PR00406 Cytochrome B5 reductase signature 154 165 2.3E-9 T 12-10-2018 IPR001834 NADH:cytochrome b5 reductase (CBR) GO:0016491|GO:0055114 Reactome: R-HSA-1237044 VAPA_1c12970 717896b719e7406d486b92cddaa0a1b9 364 PRINTS PR00406 Cytochrome B5 reductase signature 92 106 2.3E-9 T 12-10-2018 IPR001834 NADH:cytochrome b5 reductase (CBR) GO:0016491|GO:0055114 Reactome: R-HSA-1237044 VAPA_1c12970 717896b719e7406d486b92cddaa0a1b9 364 PRINTS PR00406 Cytochrome B5 reductase signature 35 46 2.3E-9 T 12-10-2018 IPR001834 NADH:cytochrome b5 reductase (CBR) GO:0016491|GO:0055114 Reactome: R-HSA-1237044 VAPA_1c12970 717896b719e7406d486b92cddaa0a1b9 364 PRINTS PR00406 Cytochrome B5 reductase signature 117 136 2.3E-9 T 12-10-2018 IPR001834 NADH:cytochrome b5 reductase (CBR) GO:0016491|GO:0055114 Reactome: R-HSA-1237044 VAPA_1c12970 717896b719e7406d486b92cddaa0a1b9 364 SUPERFAMILY SSF63380 4 106 1.87E-25 T 12-10-2018 IPR017938 Riboflavin synthase-like beta-barrel VAPA_1c18880 f5d30a37e521654e3852199de86ee128 482 Gene3D G3DSA:2.40.50.140 8 91 3.8E-17 T 12-10-2018 VAPA_1c18880 f5d30a37e521654e3852199de86ee128 482 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 137 475 9.6E-17 T 12-10-2018 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 VAPA_1c18880 f5d30a37e521654e3852199de86ee128 482 TIGRFAM TIGR00479 rumA: 23S rRNA (uracil-5-)-methyltransferase RumA 28 474 1.0E-78 T 12-10-2018 VAPA_1c18880 f5d30a37e521654e3852199de86ee128 482 ProSitePatterns PS01231 RNA methyltransferase trmA family signature 2. 464 474 - T 12-10-2018 IPR030391 RNA methyltransferase TrmA, conserved site VAPA_1c18880 f5d30a37e521654e3852199de86ee128 482 Gene3D G3DSA:3.40.1350.30 144 293 4.5E-97 T 12-10-2018 VAPA_1c18880 f5d30a37e521654e3852199de86ee128 482 SUPERFAMILY SSF53335 81 479 3.85E-68 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase VAPA_1c18880 f5d30a37e521654e3852199de86ee128 482 SUPERFAMILY SSF50249 23 78 6.28E-8 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold VAPA_1c18880 f5d30a37e521654e3852199de86ee128 482 Gene3D G3DSA:3.40.50.150 97 476 4.5E-97 T 12-10-2018 VAPA_1c18880 f5d30a37e521654e3852199de86ee128 482 Hamap MF_01010 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD [rlmD]. 22 482 64.261 T 12-10-2018 IPR001566 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD GO:0003723|GO:0006396|GO:0008173 VAPA_1c40210 f38231096e153c4d5360834fde9f5288 307 Pfam PF02653 Branched-chain amino acid transport system / permease component 11 280 2.7E-37 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 VAPA_1c23520 dfe9e2794be31027bf6452fd779961ed 415 SUPERFAMILY SSF51230 2 97 8.64E-26 T 12-10-2018 IPR011053 Single hybrid motif VAPA_1c23520 dfe9e2794be31027bf6452fd779961ed 415 SUPERFAMILY SSF52777 185 414 2.54E-86 T 12-10-2018 VAPA_1c23520 dfe9e2794be31027bf6452fd779961ed 415 Pfam PF02817 e3 binding domain 114 147 3.8E-11 T 12-10-2018 IPR004167 Peripheral subunit-binding domain GO:0016746 Reactome: R-HSA-389661 VAPA_1c23520 dfe9e2794be31027bf6452fd779961ed 415 Gene3D G3DSA:2.40.50.100 2 103 3.0E-22 T 12-10-2018 VAPA_1c23520 dfe9e2794be31027bf6452fd779961ed 415 TIGRFAM TIGR01347 sucB: dihydrolipoyllysine-residue succinyltransferase, E2 component of oxoglutarate dehydrogenase (succinyl-transferring) complex 4 414 9.9E-166 T 12-10-2018 IPR006255 Dihydrolipoamide succinyltransferase GO:0004149|GO:0006099|GO:0045252 KEGG: 00020+2.3.1.61|KEGG: 00310+2.3.1.61|MetaCyc: PWY-5084|Reactome: R-HSA-389661|Reactome: R-HSA-71064|Reactome: R-HSA-71403 VAPA_1c23520 dfe9e2794be31027bf6452fd779961ed 415 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 28 57 - T 12-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 VAPA_1c23520 dfe9e2794be31027bf6452fd779961ed 415 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 184 412 1.6E-78 T 12-10-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0016746 Reactome: R-HSA-389661 VAPA_1c23520 dfe9e2794be31027bf6452fd779961ed 415 SUPERFAMILY SSF47005 108 151 1.96E-9 T 12-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 VAPA_1c23520 dfe9e2794be31027bf6452fd779961ed 415 Pfam PF00364 Biotin-requiring enzyme 5 77 6.5E-21 T 12-10-2018 IPR000089 Biotin/lipoyl attachment VAPA_1c23520 dfe9e2794be31027bf6452fd779961ed 415 Gene3D G3DSA:4.10.320.10 107 152 7.8E-11 T 12-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 VAPA_1c23520 dfe9e2794be31027bf6452fd779961ed 415 Gene3D G3DSA:3.30.559.10 183 415 1.0E-91 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 VAPA_1c19540 1e656bf5868a4ed0c006d1717faee390 336 SUPERFAMILY SSF53850 32 269 1.74E-36 T 12-10-2018 VAPA_1c19540 1e656bf5868a4ed0c006d1717faee390 336 Gene3D G3DSA:3.40.190.10 37 295 4.3E-67 T 12-10-2018 VAPA_1c19540 1e656bf5868a4ed0c006d1717faee390 336 Gene3D G3DSA:3.40.190.10 116 219 4.3E-67 T 12-10-2018 VAPA_1c19540 1e656bf5868a4ed0c006d1717faee390 336 Pfam PF09084 NMT1/THI5 like 46 258 1.6E-46 T 12-10-2018 IPR015168 SsuA/THI5-like VAPA_1c08800 1515b2b1f2ab7eb621d32ce31885ef5d 254 Gene3D G3DSA:1.10.12.10 197 253 9.2E-13 T 12-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal VAPA_1c08800 1515b2b1f2ab7eb621d32ce31885ef5d 254 SUPERFAMILY SSF52096 2 252 1.17E-71 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily VAPA_1c08800 1515b2b1f2ab7eb621d32ce31885ef5d 254 Gene3D G3DSA:3.90.226.10 2 196 2.6E-59 T 12-10-2018 VAPA_1c08800 1515b2b1f2ab7eb621d32ce31885ef5d 254 Pfam PF00378 Enoyl-CoA hydratase/isomerase 8 252 1.2E-49 T 12-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 VAPA_1c24240 d8959054ea3562ed87f8f2cfeb6f9a27 248 Pfam PF07729 FCD domain 104 226 1.2E-27 T 12-10-2018 IPR011711 GntR, C-terminal VAPA_1c24240 d8959054ea3562ed87f8f2cfeb6f9a27 248 Gene3D G3DSA:1.20.120.530 101 244 6.7E-30 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal VAPA_1c24240 d8959054ea3562ed87f8f2cfeb6f9a27 248 SUPERFAMILY SSF46785 27 98 2.29E-18 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c24240 d8959054ea3562ed87f8f2cfeb6f9a27 248 SUPERFAMILY SSF48008 102 235 1.36E-27 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal VAPA_1c24240 d8959054ea3562ed87f8f2cfeb6f9a27 248 Gene3D G3DSA:1.10.10.10 28 94 1.3E-21 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c24240 d8959054ea3562ed87f8f2cfeb6f9a27 248 Pfam PF00392 Bacterial regulatory proteins, gntR family 32 90 6.9E-18 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_1c24240 d8959054ea3562ed87f8f2cfeb6f9a27 248 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 53 67 1.9E-6 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_1c24240 d8959054ea3562ed87f8f2cfeb6f9a27 248 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 67 83 1.9E-6 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_1c24240 d8959054ea3562ed87f8f2cfeb6f9a27 248 SMART SM00345 35 94 2.9E-17 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_1c24240 d8959054ea3562ed87f8f2cfeb6f9a27 248 SMART SM00895 104 228 4.6E-19 T 12-10-2018 IPR011711 GntR, C-terminal VAPA_1c24030 04510f1c545d21a8ede28b0c81e48b54 320 SMART SM00347 33 136 2.2E-10 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 VAPA_1c24030 04510f1c545d21a8ede28b0c81e48b54 320 Gene3D G3DSA:1.10.10.10 9 148 5.6E-27 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c24030 04510f1c545d21a8ede28b0c81e48b54 320 SUPERFAMILY SSF55729 159 303 1.89E-24 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase VAPA_1c24030 04510f1c545d21a8ede28b0c81e48b54 320 Pfam PF12802 MarR family 41 100 4.2E-14 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 VAPA_1c24030 04510f1c545d21a8ede28b0c81e48b54 320 Gene3D G3DSA:3.40.630.30 191 309 9.1E-21 T 12-10-2018 VAPA_1c24030 04510f1c545d21a8ede28b0c81e48b54 320 Pfam PF00583 Acetyltransferase (GNAT) family 202 295 3.0E-11 T 12-10-2018 IPR000182 GNAT domain VAPA_1c24030 04510f1c545d21a8ede28b0c81e48b54 320 SUPERFAMILY SSF46785 14 151 8.14E-25 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c43090 d4dc97953f5d021aa6f13d51514e8ae9 217 SUPERFAMILY SSF64438 39 189 2.75E-45 T 12-10-2018 IPR011324 Cytotoxic necrotizing factor-like, catalytic VAPA_1c43090 d4dc97953f5d021aa6f13d51514e8ae9 217 Gene3D G3DSA:3.30.1330.200 38 194 1.9E-46 T 12-10-2018 IPR038592 CheD-like superfamily VAPA_1c43090 d4dc97953f5d021aa6f13d51514e8ae9 217 Pfam PF03975 CheD chemotactic sensory transduction 81 185 2.3E-30 T 12-10-2018 IPR005659 Chemoreceptor glutamine deamidase CheD GO:0006935|GO:0050568 VAPA_1c43090 d4dc97953f5d021aa6f13d51514e8ae9 217 Hamap MF_01440 Chemoreceptor glutamine deamidase CheD [cheD]. 33 189 27.656 T 12-10-2018 IPR005659 Chemoreceptor glutamine deamidase CheD GO:0006935|GO:0050568 VAPA_1c28290 9c380ec9b7208754ea988c3a2a21988e 511 ProSitePatterns PS00631 Cytosol aminopeptidase signature. 335 342 - T 12-10-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 VAPA_1c28290 9c380ec9b7208754ea988c3a2a21988e 511 Gene3D G3DSA:3.40.220.10 1 168 4.4E-12 T 12-10-2018 VAPA_1c28290 9c380ec9b7208754ea988c3a2a21988e 511 PRINTS PR00481 Cytosol aminopeptidase signature 309 330 6.0E-54 T 12-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 VAPA_1c28290 9c380ec9b7208754ea988c3a2a21988e 511 PRINTS PR00481 Cytosol aminopeptidase signature 272 293 6.0E-54 T 12-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 VAPA_1c28290 9c380ec9b7208754ea988c3a2a21988e 511 PRINTS PR00481 Cytosol aminopeptidase signature 359 374 6.0E-54 T 12-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 VAPA_1c28290 9c380ec9b7208754ea988c3a2a21988e 511 PRINTS PR00481 Cytosol aminopeptidase signature 250 267 6.0E-54 T 12-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 VAPA_1c28290 9c380ec9b7208754ea988c3a2a21988e 511 PRINTS PR00481 Cytosol aminopeptidase signature 331 351 6.0E-54 T 12-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 VAPA_1c28290 9c380ec9b7208754ea988c3a2a21988e 511 Pfam PF02789 Cytosol aminopeptidase family, N-terminal domain 36 135 4.6E-7 T 12-10-2018 IPR008283 Peptidase M17, leucyl aminopeptidase, N-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 VAPA_1c28290 9c380ec9b7208754ea988c3a2a21988e 511 Gene3D G3DSA:3.40.630.10 169 483 3.8E-133 T 12-10-2018 VAPA_1c28290 9c380ec9b7208754ea988c3a2a21988e 511 Pfam PF00883 Cytosol aminopeptidase family, catalytic domain 174 475 6.8E-121 T 12-10-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 VAPA_1c28290 9c380ec9b7208754ea988c3a2a21988e 511 Hamap MF_00181 Probable cytosol aminopeptidase [pepA]. 6 483 34.801 T 12-10-2018 IPR023042 Peptidase M17, leucine aminopeptidase KEGG: 00480+3.4.11.1 VAPA_1c28290 9c380ec9b7208754ea988c3a2a21988e 511 SUPERFAMILY SSF52949 2 172 8.24E-14 T 12-10-2018 VAPA_1c28290 9c380ec9b7208754ea988c3a2a21988e 511 SUPERFAMILY SSF53187 168 481 1.35E-117 T 12-10-2018 VAPA_1c52180 810e07f3c1eda0f45f7e463a639a2eda 288 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 2 61 5.1E-21 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c52180 810e07f3c1eda0f45f7e463a639a2eda 288 SUPERFAMILY SSF46785 3 108 8.46E-21 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c52180 810e07f3c1eda0f45f7e463a639a2eda 288 Gene3D G3DSA:3.40.190.290 88 288 6.0E-29 T 12-10-2018 VAPA_1c52180 810e07f3c1eda0f45f7e463a639a2eda 288 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 17 28 3.0E-9 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c52180 810e07f3c1eda0f45f7e463a639a2eda 288 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 38 49 3.0E-9 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c52180 810e07f3c1eda0f45f7e463a639a2eda 288 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 28 38 3.0E-9 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c52180 810e07f3c1eda0f45f7e463a639a2eda 288 Gene3D G3DSA:1.10.10.10 1 80 3.0E-23 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c52180 810e07f3c1eda0f45f7e463a639a2eda 288 SUPERFAMILY SSF53850 88 288 4.71E-32 T 12-10-2018 VAPA_1c52180 810e07f3c1eda0f45f7e463a639a2eda 288 Pfam PF03466 LysR substrate binding domain 86 287 2.0E-33 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_1c14110 7437167409976cded5733b729e3670a7 222 SMART SM00448 4 125 3.2E-23 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_1c14110 7437167409976cded5733b729e3670a7 222 SMART SM00421 155 212 8.5E-19 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_1c14110 7437167409976cded5733b729e3670a7 222 ProSitePatterns PS00622 LuxR-type HTH domain signature. 172 199 - T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_1c14110 7437167409976cded5733b729e3670a7 222 SUPERFAMILY SSF52172 1 131 3.7E-29 T 12-10-2018 IPR011006 CheY-like superfamily VAPA_1c14110 7437167409976cded5733b729e3670a7 222 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 188 200 1.4E-8 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_1c14110 7437167409976cded5733b729e3670a7 222 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 158 172 1.4E-8 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_1c14110 7437167409976cded5733b729e3670a7 222 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 172 188 1.4E-8 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_1c14110 7437167409976cded5733b729e3670a7 222 Gene3D G3DSA:3.40.50.12740 4 217 2.4E-55 T 12-10-2018 VAPA_1c14110 7437167409976cded5733b729e3670a7 222 SUPERFAMILY SSF46894 151 216 2.24E-17 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 VAPA_1c14110 7437167409976cded5733b729e3670a7 222 Pfam PF00072 Response regulator receiver domain 6 125 9.5E-25 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_1c14110 7437167409976cded5733b729e3670a7 222 Pfam PF00196 Bacterial regulatory proteins, luxR family 157 212 1.1E-14 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_1c18570 2ec71c8308437fd90e83f83d6b171625 77 SUPERFAMILY SSF69047 1 64 2.22E-26 T 12-10-2018 IPR036629 YjbJ superfamily VAPA_1c18570 2ec71c8308437fd90e83f83d6b171625 77 PIRSF PIRSF039008 1 65 2.9E-32 T 12-10-2018 IPR026042 Stress response protein YjbJ VAPA_1c18570 2ec71c8308437fd90e83f83d6b171625 77 Pfam PF05532 CsbD-like 4 56 8.3E-20 T 12-10-2018 IPR008462 CsbD-like domain VAPA_1c18570 2ec71c8308437fd90e83f83d6b171625 77 Gene3D G3DSA:1.10.1470.10 1 67 5.2E-33 T 12-10-2018 IPR036629 YjbJ superfamily VAPA_1c53680 212012cfc6eaed0cce8b4de19b8bb65b 163 Hamap MF_01224_B Cyclic pyranopterin monophosphate synthase [moaC]. 2 160 35.86 T 12-10-2018 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 VAPA_1c53680 212012cfc6eaed0cce8b4de19b8bb65b 163 Gene3D G3DSA:3.30.70.640 1 160 5.9E-69 T 12-10-2018 IPR036522 Molybdopterin cofactor biosynthesis C (MoaC) domain superfamily GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 VAPA_1c53680 212012cfc6eaed0cce8b4de19b8bb65b 163 TIGRFAM TIGR00581 moaC: molybdenum cofactor biosynthesis protein C 4 154 1.8E-60 T 12-10-2018 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 VAPA_1c53680 212012cfc6eaed0cce8b4de19b8bb65b 163 SUPERFAMILY SSF55040 11 157 6.54E-58 T 12-10-2018 IPR036522 Molybdopterin cofactor biosynthesis C (MoaC) domain superfamily GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 VAPA_1c53680 212012cfc6eaed0cce8b4de19b8bb65b 163 Pfam PF01967 MoaC family 15 152 1.4E-54 T 12-10-2018 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 VAPA_1c41830 7c3417415231fc820218d2a63bcda7ac 407 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 299 6.5E-54 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 VAPA_1c41830 7c3417415231fc820218d2a63bcda7ac 407 Gene3D G3DSA:3.50.50.60 112 236 4.3E-90 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c41830 7c3417415231fc820218d2a63bcda7ac 407 Pfam PF14759 Reductase C-terminal 318 404 1.8E-23 T 12-10-2018 IPR028202 Reductase, C-terminal VAPA_1c41830 7c3417415231fc820218d2a63bcda7ac 407 Gene3D G3DSA:3.50.50.60 4 300 4.3E-90 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c41830 7c3417415231fc820218d2a63bcda7ac 407 SUPERFAMILY SSF51905 3 189 5.62E-39 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c41830 7c3417415231fc820218d2a63bcda7ac 407 Gene3D G3DSA:3.30.390.30 318 406 3.3E-27 T 12-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 VAPA_1c41830 7c3417415231fc820218d2a63bcda7ac 407 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 269 276 3.4E-15 T 12-10-2018 VAPA_1c41830 7c3417415231fc820218d2a63bcda7ac 407 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 230 244 3.4E-15 T 12-10-2018 VAPA_1c41830 7c3417415231fc820218d2a63bcda7ac 407 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 3 25 3.4E-15 T 12-10-2018 VAPA_1c41830 7c3417415231fc820218d2a63bcda7ac 407 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 144 169 3.4E-15 T 12-10-2018 VAPA_1c41830 7c3417415231fc820218d2a63bcda7ac 407 SUPERFAMILY SSF55424 310 406 1.65E-20 T 12-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 VAPA_1c41830 7c3417415231fc820218d2a63bcda7ac 407 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 254 276 5.1E-21 T 12-10-2018 VAPA_1c41830 7c3417415231fc820218d2a63bcda7ac 407 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 99 117 5.1E-21 T 12-10-2018 VAPA_1c41830 7c3417415231fc820218d2a63bcda7ac 407 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 144 162 5.1E-21 T 12-10-2018 VAPA_1c41830 7c3417415231fc820218d2a63bcda7ac 407 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 5.1E-21 T 12-10-2018 VAPA_1c41830 7c3417415231fc820218d2a63bcda7ac 407 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 229 245 5.1E-21 T 12-10-2018 VAPA_1c41830 7c3417415231fc820218d2a63bcda7ac 407 SUPERFAMILY SSF51905 144 311 6.48E-26 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c29270 e18ea8ec1310e7b2ef000fda633a5b82 296 TIGRFAM TIGR01496 DHPS: dihydropteroate synthase 23 279 3.5E-89 T 12-10-2018 IPR006390 Dihydropteroate synthase GO:0004156|GO:0009396 KEGG: 00790+2.5.1.15|MetaCyc: PWY-6614 VAPA_1c29270 e18ea8ec1310e7b2ef000fda633a5b82 296 SUPERFAMILY SSF51717 9 280 5.63E-94 T 12-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 VAPA_1c29270 e18ea8ec1310e7b2ef000fda633a5b82 296 Gene3D G3DSA:3.20.20.20 2 287 3.0E-101 T 12-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 VAPA_1c29270 e18ea8ec1310e7b2ef000fda633a5b82 296 Pfam PF00809 Pterin binding enzyme 24 264 5.3E-75 T 12-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 VAPA_1c29270 e18ea8ec1310e7b2ef000fda633a5b82 296 ProSitePatterns PS00792 Dihydropteroate synthase signature 1. 23 38 - T 12-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 VAPA_1c29270 e18ea8ec1310e7b2ef000fda633a5b82 296 ProSitePatterns PS00793 Dihydropteroate synthase signature 2. 57 70 - T 12-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 VAPA_1c39640 0b04e35f346f57864ed2ac2b23a6034b 324 SUPERFAMILY SSF161098 94 308 7.03E-20 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c39640 0b04e35f346f57864ed2ac2b23a6034b 324 Gene3D G3DSA:1.10.3720.10 89 317 2.3E-23 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c39640 0b04e35f346f57864ed2ac2b23a6034b 324 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 117 322 4.1E-43 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 VAPA_1c12760 4771810aa8e877acf0cc0dc139f34e76 279 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 94 277 1.5E-27 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 VAPA_1c12760 4771810aa8e877acf0cc0dc139f34e76 279 Gene3D G3DSA:1.10.3720.10 66 269 9.6E-24 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c12760 4771810aa8e877acf0cc0dc139f34e76 279 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 5 44 3.7E-5 T 12-10-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain VAPA_1c12760 4771810aa8e877acf0cc0dc139f34e76 279 SUPERFAMILY SSF161098 70 257 6.93E-29 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c29900 d547b691512e53d6310b03069d115110 1092 SUPERFAMILY SSF82866 841 1038 2.62E-45 T 12-10-2018 VAPA_1c29900 d547b691512e53d6310b03069d115110 1092 Gene3D G3DSA:3.30.70.1430 577 678 0.0 T 12-10-2018 VAPA_1c29900 d547b691512e53d6310b03069d115110 1092 SUPERFAMILY SSF82866 299 500 1.28E-52 T 12-10-2018 VAPA_1c29900 d547b691512e53d6310b03069d115110 1092 SUPERFAMILY SSF82714 185 274 3.66E-19 T 12-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains VAPA_1c29900 d547b691512e53d6310b03069d115110 1092 Gene3D G3DSA:3.30.2090.10 181 278 0.0 T 12-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains VAPA_1c29900 d547b691512e53d6310b03069d115110 1092 SUPERFAMILY SSF82714 732 817 8.63E-20 T 12-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains VAPA_1c29900 d547b691512e53d6310b03069d115110 1092 PRINTS PR00702 Acriflavin resistance protein family signature 394 418 1.1E-95 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 VAPA_1c29900 d547b691512e53d6310b03069d115110 1092 PRINTS PR00702 Acriflavin resistance protein family signature 562 579 1.1E-95 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 VAPA_1c29900 d547b691512e53d6310b03069d115110 1092 PRINTS PR00702 Acriflavin resistance protein family signature 339 362 1.1E-95 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 VAPA_1c29900 d547b691512e53d6310b03069d115110 1092 PRINTS PR00702 Acriflavin resistance protein family signature 631 645 1.1E-95 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 VAPA_1c29900 d547b691512e53d6310b03069d115110 1092 PRINTS PR00702 Acriflavin resistance protein family signature 10 34 1.1E-95 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 VAPA_1c29900 d547b691512e53d6310b03069d115110 1092 PRINTS PR00702 Acriflavin resistance protein family signature 366 387 1.1E-95 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 VAPA_1c29900 d547b691512e53d6310b03069d115110 1092 PRINTS PR00702 Acriflavin resistance protein family signature 472 495 1.1E-95 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 VAPA_1c29900 d547b691512e53d6310b03069d115110 1092 PRINTS PR00702 Acriflavin resistance protein family signature 38 56 1.1E-95 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 VAPA_1c29900 d547b691512e53d6310b03069d115110 1092 PRINTS PR00702 Acriflavin resistance protein family signature 447 470 1.1E-95 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 VAPA_1c29900 d547b691512e53d6310b03069d115110 1092 TIGRFAM TIGR00915 2A0602: RND transporter, hydrophobe/amphiphile efflux-1 (HAE1) family 3 1042 0.0 T 12-10-2018 IPR004764 Hydrophobe/amphiphile efflux-1 HAE1 GO:0006855|GO:0015562|GO:0016021 VAPA_1c29900 d547b691512e53d6310b03069d115110 1092 Gene3D G3DSA:3.30.2090.10 731 819 0.0 T 12-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains VAPA_1c29900 d547b691512e53d6310b03069d115110 1092 SUPERFAMILY SSF82693 682 867 3.4E-27 T 12-10-2018 VAPA_1c29900 d547b691512e53d6310b03069d115110 1092 SUPERFAMILY SSF82693 138 333 1.2E-28 T 12-10-2018 VAPA_1c29900 d547b691512e53d6310b03069d115110 1092 Gene3D G3DSA:3.30.70.1320 135 335 0.0 T 12-10-2018 VAPA_1c29900 d547b691512e53d6310b03069d115110 1092 Gene3D G3DSA:3.30.70.1430 40 827 0.0 T 12-10-2018 VAPA_1c29900 d547b691512e53d6310b03069d115110 1092 Gene3D G3DSA:3.30.70.1440 679 876 0.0 T 12-10-2018 VAPA_1c29900 d547b691512e53d6310b03069d115110 1092 Gene3D G3DSA:1.20.1640.10 523 1033 0.0 T 12-10-2018 VAPA_1c29900 d547b691512e53d6310b03069d115110 1092 SUPERFAMILY SSF82693 575 681 2.2E-27 T 12-10-2018 VAPA_1c29900 d547b691512e53d6310b03069d115110 1092 Gene3D G3DSA:1.20.1640.10 10 522 0.0 T 12-10-2018 VAPA_1c29900 d547b691512e53d6310b03069d115110 1092 Pfam PF00873 AcrB/AcrD/AcrF family 4 1036 0.0 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 VAPA_1c29900 d547b691512e53d6310b03069d115110 1092 SUPERFAMILY SSF82693 40 133 2.41E-26 T 12-10-2018 VAPA_1c39480 f924a260ff4b637af4724f5e96210277 552 Gene3D G3DSA:3.30.410.40 152 477 1.3E-185 T 12-10-2018 VAPA_1c39480 f924a260ff4b637af4724f5e96210277 552 PIRSF PIRSF000137 1 546 9.2E-159 T 12-10-2018 IPR012132 Glucose-methanol-choline oxidoreductase GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 VAPA_1c39480 f924a260ff4b637af4724f5e96210277 552 Gene3D G3DSA:3.50.50.60 5 534 1.3E-185 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c39480 f924a260ff4b637af4724f5e96210277 552 Gene3D G3DSA:1.10.1220.110 98 151 1.3E-185 T 12-10-2018 VAPA_1c39480 f924a260ff4b637af4724f5e96210277 552 SUPERFAMILY SSF54373 291 480 1.28E-57 T 12-10-2018 VAPA_1c39480 f924a260ff4b637af4724f5e96210277 552 ProSitePatterns PS00623 GMC oxidoreductases signature 1. 83 106 - T 12-10-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 VAPA_1c39480 f924a260ff4b637af4724f5e96210277 552 Gene3D G3DSA:4.10.450.10 39 197 1.3E-185 T 12-10-2018 IPR027424 Glucose Oxidase, domain 2 KEGG: 00260+1.2.1.8+1.1.99.1|MetaCyc: PWY-3722|MetaCyc: PWY-7494|Reactome: R-HSA-6798163 VAPA_1c39480 f924a260ff4b637af4724f5e96210277 552 SUPERFAMILY SSF51905 2 538 1.35E-93 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c39480 f924a260ff4b637af4724f5e96210277 552 ProSitePatterns PS00624 GMC oxidoreductases signature 2. 255 269 - T 12-10-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 VAPA_1c39480 f924a260ff4b637af4724f5e96210277 552 Pfam PF00732 GMC oxidoreductase 6 296 1.3E-91 T 12-10-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 VAPA_1c39480 f924a260ff4b637af4724f5e96210277 552 Pfam PF05199 GMC oxidoreductase 394 530 7.2E-41 T 12-10-2018 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 VAPA_1c32150 137ae23105a9a471faa4bd2a6ea38757 569 SUPERFAMILY SSF54523 441 560 1.22E-11 T 12-10-2018 VAPA_1c32150 137ae23105a9a471faa4bd2a6ea38757 569 Pfam PF05658 Head domain of trimeric autotransporter adhesin 361 385 3.2E-5 T 12-10-2018 IPR008640 Head domain of trimeric autotransporter adhesin GO:0009405|GO:0019867 VAPA_1c32150 137ae23105a9a471faa4bd2a6ea38757 569 Pfam PF05658 Head domain of trimeric autotransporter adhesin 373 399 2.6E-7 T 12-10-2018 IPR008640 Head domain of trimeric autotransporter adhesin GO:0009405|GO:0019867 VAPA_1c32150 137ae23105a9a471faa4bd2a6ea38757 569 Gene3D G3DSA:3.30.1300.30 476 566 4.5E-12 T 12-10-2018 VAPA_1c32150 137ae23105a9a471faa4bd2a6ea38757 569 Gene3D G3DSA:2.150.10.10 332 473 8.0E-25 T 12-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal VAPA_1c30220 1972b9527b8beb6874e0347f2ffa7209 320 SUPERFAMILY SSF46785 6 88 1.75E-22 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c30220 1972b9527b8beb6874e0347f2ffa7209 320 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 67 3.4E-20 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c30220 1972b9527b8beb6874e0347f2ffa7209 320 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 44 55 1.6E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c30220 1972b9527b8beb6874e0347f2ffa7209 320 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 44 1.6E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c30220 1972b9527b8beb6874e0347f2ffa7209 320 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 23 34 1.6E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c30220 1972b9527b8beb6874e0347f2ffa7209 320 Pfam PF03466 LysR substrate binding domain 92 307 4.3E-37 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_1c30220 1972b9527b8beb6874e0347f2ffa7209 320 SUPERFAMILY SSF53850 95 308 2.41E-33 T 12-10-2018 VAPA_1c30220 1972b9527b8beb6874e0347f2ffa7209 320 Gene3D G3DSA:1.10.10.10 2 90 1.4E-28 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c30220 1972b9527b8beb6874e0347f2ffa7209 320 Gene3D G3DSA:3.40.190.10 93 302 1.3E-51 T 12-10-2018 VAPA_1c30220 1972b9527b8beb6874e0347f2ffa7209 320 Gene3D G3DSA:3.40.190.10 169 283 1.3E-51 T 12-10-2018 VAPA_1c42280 08919663f41315fc630326a53232304f 397 Gene3D G3DSA:3.40.1090.10 129 268 1.5E-5 T 12-10-2018 VAPA_1c42280 08919663f41315fc630326a53232304f 397 Gene3D G3DSA:3.40.1090.10 2 119 3.0E-20 T 12-10-2018 VAPA_1c42280 08919663f41315fc630326a53232304f 397 Pfam PF01734 Patatin-like phospholipase 10 235 1.9E-19 T 12-10-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 VAPA_1c42280 08919663f41315fc630326a53232304f 397 SUPERFAMILY SSF52151 6 284 1.54E-42 T 12-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase VAPA_1c50240 42e8a956d824cb4ae6621dda7f59be60 371 ProSitePatterns PS00211 ABC transporters family signature. 150 164 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_1c50240 42e8a956d824cb4ae6621dda7f59be60 371 SUPERFAMILY SSF52540 18 256 4.64E-86 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c50240 42e8a956d824cb4ae6621dda7f59be60 371 SMART SM00382 44 227 8.4E-14 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c50240 42e8a956d824cb4ae6621dda7f59be60 371 SUPERFAMILY SSF50331 254 368 1.42E-11 T 12-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal VAPA_1c50240 42e8a956d824cb4ae6621dda7f59be60 371 Gene3D G3DSA:2.40.50.940 238 364 2.4E-10 T 12-10-2018 VAPA_1c50240 42e8a956d824cb4ae6621dda7f59be60 371 Gene3D G3DSA:2.40.50.140 305 359 2.4E-10 T 12-10-2018 VAPA_1c50240 42e8a956d824cb4ae6621dda7f59be60 371 Pfam PF08402 TOBE domain 298 366 2.0E-13 T 12-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 VAPA_1c50240 42e8a956d824cb4ae6621dda7f59be60 371 Gene3D G3DSA:3.40.50.300 18 237 8.2E-64 T 12-10-2018 VAPA_1c50240 42e8a956d824cb4ae6621dda7f59be60 371 Pfam PF00005 ABC transporter 37 177 1.4E-33 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_2c11990 af261fcc08462af4020cb91fae07c271 491 ProSitePatterns PS00523 Sulfatases signature 1. 79 91 - T 12-10-2018 IPR024607 Sulfatase, conserved site VAPA_2c11990 af261fcc08462af4020cb91fae07c271 491 Gene3D G3DSA:3.40.720.10 32 415 6.5E-113 T 12-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 VAPA_2c11990 af261fcc08462af4020cb91fae07c271 491 Pfam PF00884 Sulfatase 33 382 4.6E-67 T 12-10-2018 IPR000917 Sulfatase, N-terminal GO:0008484 VAPA_2c11990 af261fcc08462af4020cb91fae07c271 491 Gene3D G3DSA:3.30.1120.10 416 473 6.5E-113 T 12-10-2018 VAPA_2c11990 af261fcc08462af4020cb91fae07c271 491 SUPERFAMILY SSF53649 32 475 3.14E-111 T 12-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 VAPA_1c49920 0426b3b87724d22e3c736534c1c6ed97 210 Hamap MF_01216 FMN-dependent NADH-azoreductase [azoR]. 2 207 22.735 T 12-10-2018 IPR023048 NADH-azoreductase, FMN-dependent GO:0016661|GO:0055114 VAPA_1c49920 0426b3b87724d22e3c736534c1c6ed97 210 Gene3D G3DSA:3.40.50.360 1 209 6.8E-45 T 12-10-2018 IPR029039 Flavoprotein-like superfamily VAPA_1c49920 0426b3b87724d22e3c736534c1c6ed97 210 SUPERFAMILY SSF52218 1 208 1.54E-35 T 12-10-2018 IPR029039 Flavoprotein-like superfamily VAPA_1c49920 0426b3b87724d22e3c736534c1c6ed97 210 Pfam PF02525 Flavodoxin-like fold 3 205 2.7E-36 T 12-10-2018 IPR003680 Flavodoxin-like fold VAPA_1c15850 587a93b50a848be5e3ae7ad3a5cd720f 437 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 78 98 1.0E-31 T 12-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 VAPA_1c15850 587a93b50a848be5e3ae7ad3a5cd720f 437 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 27 52 1.0E-31 T 12-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 VAPA_1c15850 587a93b50a848be5e3ae7ad3a5cd720f 437 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 188 210 1.0E-31 T 12-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 VAPA_1c15850 587a93b50a848be5e3ae7ad3a5cd720f 437 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 57 72 1.0E-31 T 12-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 VAPA_1c15850 587a93b50a848be5e3ae7ad3a5cd720f 437 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 100 120 1.0E-31 T 12-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 VAPA_1c15850 587a93b50a848be5e3ae7ad3a5cd720f 437 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 146 172 1.0E-31 T 12-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 VAPA_1c15850 587a93b50a848be5e3ae7ad3a5cd720f 437 SUPERFAMILY SSF55961 163 436 1.18E-54 T 12-10-2018 VAPA_1c15850 587a93b50a848be5e3ae7ad3a5cd720f 437 Pfam PF00355 Rieske [2Fe-2S] domain 42 126 8.3E-18 T 12-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 VAPA_1c15850 587a93b50a848be5e3ae7ad3a5cd720f 437 Gene3D G3DSA:3.90.380.10 19 433 2.7E-96 T 12-10-2018 VAPA_1c15850 587a93b50a848be5e3ae7ad3a5cd720f 437 Pfam PF00848 Ring hydroxylating alpha subunit (catalytic domain) 201 434 1.3E-15 T 12-10-2018 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0044237|GO:0051537|GO:0055114 VAPA_1c15850 587a93b50a848be5e3ae7ad3a5cd720f 437 Gene3D G3DSA:2.102.10.10 40 171 2.7E-96 T 12-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 VAPA_1c15850 587a93b50a848be5e3ae7ad3a5cd720f 437 SUPERFAMILY SSF50022 9 161 1.96E-44 T 12-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 VAPA_2c01590 05142c5b9dd920ba24d621693e192215 330 SUPERFAMILY SSF51735 4 155 2.91E-13 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_2c01590 05142c5b9dd920ba24d621693e192215 330 Gene3D G3DSA:3.40.50.720 4 157 6.9E-22 T 12-10-2018 VAPA_2c01590 05142c5b9dd920ba24d621693e192215 330 Pfam PF03435 Saccharopine dehydrogenase NADP binding domain 7 123 1.9E-7 T 12-10-2018 IPR005097 Saccharopine dehydrogenase, NADP binding domain GO:0016491|GO:0055114 VAPA_1c24530 717472ab86f9b993a6a95ad20a9f5212 294 SUPERFAMILY SSF161098 37 285 2.62E-32 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c24530 717472ab86f9b993a6a95ad20a9f5212 294 Gene3D G3DSA:1.10.3720.10 76 293 3.8E-29 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c24530 717472ab86f9b993a6a95ad20a9f5212 294 TIGRFAM TIGR00974 3a0107s02c: phosphate ABC transporter, permease protein PstA 30 292 3.8E-85 T 12-10-2018 IPR005672 Phosphate transport system permease protein PstA GO:0005315|GO:0005887|GO:0035435 VAPA_1c24530 717472ab86f9b993a6a95ad20a9f5212 294 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 101 291 8.1E-27 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 VAPA_1c55090 84d9910dcf3216ea8f7305ad00c7ecae 475 Pfam PF10396 GTP-binding protein TrmE N-terminus 10 136 5.3E-33 T 12-10-2018 IPR018948 GTP-binding protein TrmE, N-terminal Reactome: R-HSA-6787450 VAPA_1c55090 84d9910dcf3216ea8f7305ad00c7ecae 475 SUPERFAMILY SSF116878 137 475 1.44E-48 T 12-10-2018 VAPA_1c55090 84d9910dcf3216ea8f7305ad00c7ecae 475 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 232 358 3.7E-19 T 12-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 VAPA_1c55090 84d9910dcf3216ea8f7305ad00c7ecae 475 Gene3D G3DSA:3.30.1360.120 1 137 6.0E-37 T 12-10-2018 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 VAPA_1c55090 84d9910dcf3216ea8f7305ad00c7ecae 475 Gene3D G3DSA:1.20.120.430 138 475 2.5E-98 T 12-10-2018 IPR027368 tRNA modification GTPase MnmE domain 2 Reactome: R-HSA-6787450 VAPA_1c55090 84d9910dcf3216ea8f7305ad00c7ecae 475 Gene3D G3DSA:3.40.50.300 233 402 2.5E-98 T 12-10-2018 VAPA_1c55090 84d9910dcf3216ea8f7305ad00c7ecae 475 SUPERFAMILY SSF52540 74 392 5.71E-43 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c55090 84d9910dcf3216ea8f7305ad00c7ecae 475 Hamap MF_00379 tRNA modification GTPase MnmE [mnmE]. 8 475 31.708 T 12-10-2018 IPR004520 tRNA modification GTPase MnmE GO:0003924|GO:0005525|GO:0005622|GO:0006400 Reactome: R-HSA-6787450 VAPA_1c55090 84d9910dcf3216ea8f7305ad00c7ecae 475 Pfam PF12631 MnmE helical domain 139 472 1.4E-57 T 12-10-2018 IPR025867 MnmE, helical domain Reactome: R-HSA-6787450 VAPA_1c55090 84d9910dcf3216ea8f7305ad00c7ecae 475 TIGRFAM TIGR00450 mnmE_trmE_thdF: tRNA modification GTPase TrmE 14 475 2.4E-88 T 12-10-2018 IPR004520 tRNA modification GTPase MnmE GO:0003924|GO:0005525|GO:0005622|GO:0006400 Reactome: R-HSA-6787450 VAPA_1c55090 84d9910dcf3216ea8f7305ad00c7ecae 475 Pfam PF01926 50S ribosome-binding GTPase 234 355 1.8E-22 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 VAPA_1c55090 84d9910dcf3216ea8f7305ad00c7ecae 475 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 284 299 3.4E-5 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 VAPA_1c55090 84d9910dcf3216ea8f7305ad00c7ecae 475 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 235 255 3.4E-5 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 VAPA_1c01680 07b2bccc15b776f6cbeb76242b0ee638 255 Pfam PF00005 ABC transporter 26 179 1.3E-26 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c01680 07b2bccc15b776f6cbeb76242b0ee638 255 SUPERFAMILY SSF52540 8 250 1.33E-51 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c01680 07b2bccc15b776f6cbeb76242b0ee638 255 Gene3D G3DSA:3.40.50.300 4 251 1.9E-49 T 12-10-2018 VAPA_1c01680 07b2bccc15b776f6cbeb76242b0ee638 255 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 227 249 4.1E-9 T 12-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal VAPA_1c01680 07b2bccc15b776f6cbeb76242b0ee638 255 SMART SM00382 33 226 3.0E-9 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c00650 a0d92f2a8ca0e902455fbabf56ebd6fc 271 TIGRFAM TIGR01968 minD_bact: septum site-determining protein MinD 2 268 6.8E-107 T 12-10-2018 IPR010223 ATP binding protein MinD, bacterial-type GO:0016887 VAPA_1c00650 a0d92f2a8ca0e902455fbabf56ebd6fc 271 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 5 226 1.4E-19 T 12-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain VAPA_1c00650 a0d92f2a8ca0e902455fbabf56ebd6fc 271 SUPERFAMILY SSF52540 1 269 2.59E-54 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c00650 a0d92f2a8ca0e902455fbabf56ebd6fc 271 PIRSF PIRSF003092 1 271 1.8E-92 T 12-10-2018 IPR025501 ATP binding protein MinD VAPA_1c00650 a0d92f2a8ca0e902455fbabf56ebd6fc 271 Gene3D G3DSA:3.40.50.300 1 260 1.3E-72 T 12-10-2018 VAPA_1c43480 b8773abac4a78d8a82afe44c4b87f512 323 TIGRFAM TIGR02541 flagell_FlgJ: flagellar rod assembly protein/muramidase FlgJ 16 321 4.9E-105 T 12-10-2018 IPR013377 Peptidoglycan hydrolase FlgJ GO:0016798|GO:0044780 VAPA_1c43480 b8773abac4a78d8a82afe44c4b87f512 323 PRINTS PR01002 Flagellar protein FlgJ signature 57 77 2.2E-8 T 12-10-2018 VAPA_1c43480 b8773abac4a78d8a82afe44c4b87f512 323 PRINTS PR01002 Flagellar protein FlgJ signature 32 55 2.2E-8 T 12-10-2018 VAPA_1c43480 b8773abac4a78d8a82afe44c4b87f512 323 PRINTS PR01002 Flagellar protein FlgJ signature 78 100 2.2E-8 T 12-10-2018 VAPA_1c43480 b8773abac4a78d8a82afe44c4b87f512 323 SMART SM00047 170 323 4.2E-43 T 12-10-2018 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 VAPA_1c43480 b8773abac4a78d8a82afe44c4b87f512 323 Pfam PF01832 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase 188 322 1.4E-20 T 12-10-2018 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 VAPA_1c43480 b8773abac4a78d8a82afe44c4b87f512 323 Pfam PF10135 Rod binding protein 54 100 3.1E-14 T 12-10-2018 IPR019301 Flagellar protein FlgJ, N-terminal VAPA_1c43480 b8773abac4a78d8a82afe44c4b87f512 323 Gene3D G3DSA:1.10.530.10 260 323 4.0E-22 T 12-10-2018 VAPA_1c43480 b8773abac4a78d8a82afe44c4b87f512 323 Gene3D G3DSA:2.10.70.40 214 259 2.1E-24 T 12-10-2018 VAPA_1c51200 7609960e4d4aa35eb9f495b419bec210 275 Gene3D G3DSA:3.40.50.300 5 264 1.3E-57 T 12-10-2018 VAPA_1c51200 7609960e4d4aa35eb9f495b419bec210 275 Pfam PF00005 ABC transporter 26 190 4.1E-27 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c51200 7609960e4d4aa35eb9f495b419bec210 275 SMART SM00382 34 248 1.5E-7 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c51200 7609960e4d4aa35eb9f495b419bec210 275 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 240 262 1.1E-9 T 12-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal VAPA_1c51200 7609960e4d4aa35eb9f495b419bec210 275 SUPERFAMILY SSF52540 8 262 3.0E-57 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c07870 cbbf92f5a06c83173a5e8c0f6adeca09 453 Gene3D G3DSA:2.120.10.30 176 443 1.4E-12 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like VAPA_1c07870 cbbf92f5a06c83173a5e8c0f6adeca09 453 SUPERFAMILY SSF50952 72 451 4.05E-33 T 12-10-2018 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 VAPA_1c07870 cbbf92f5a06c83173a5e8c0f6adeca09 453 Pfam PF07995 Glucose / Sorbosone dehydrogenase 258 376 1.0E-11 T 12-10-2018 IPR012938 Glucose/Sorbosone dehydrogenase VAPA_1c06630 29f3db91d06b964630c06125368e1676 256 SUPERFAMILY SSF51735 4 255 2.38E-74 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c06630 29f3db91d06b964630c06125368e1676 256 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 6 215 0.0061 T 12-10-2018 VAPA_1c06630 29f3db91d06b964630c06125368e1676 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 88 99 5.5E-13 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c06630 29f3db91d06b964630c06125368e1676 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 141 149 5.5E-13 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c06630 29f3db91d06b964630c06125368e1676 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 163 182 5.5E-13 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c06630 29f3db91d06b964630c06125368e1676 256 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 150 178 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 VAPA_1c06630 29f3db91d06b964630c06125368e1676 256 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 254 1.7E-65 T 12-10-2018 VAPA_1c06630 29f3db91d06b964630c06125368e1676 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 184 201 5.6E-34 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c06630 29f3db91d06b964630c06125368e1676 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 88 99 5.6E-34 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c06630 29f3db91d06b964630c06125368e1676 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 5.6E-34 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c06630 29f3db91d06b964630c06125368e1676 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 163 182 5.6E-34 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c06630 29f3db91d06b964630c06125368e1676 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 217 237 5.6E-34 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c06630 29f3db91d06b964630c06125368e1676 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 135 151 5.6E-34 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c06630 29f3db91d06b964630c06125368e1676 256 Gene3D G3DSA:3.40.50.720 2 256 1.6E-73 T 12-10-2018 VAPA_1c53600 177d627ba9896d5fe950930963eacb41 723 SUPERFAMILY SSF56935 41 723 8.24E-114 T 12-10-2018 VAPA_1c53600 177d627ba9896d5fe950930963eacb41 723 Pfam PF00593 TonB dependent receptor 259 721 1.8E-55 T 12-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel VAPA_1c53600 177d627ba9896d5fe950930963eacb41 723 ProSitePatterns PS01156 TonB-dependent receptor proteins signature 2. 706 723 - T 12-10-2018 IPR010917 TonB-dependent receptor, conserved site VAPA_1c53600 177d627ba9896d5fe950930963eacb41 723 Gene3D G3DSA:2.170.130.10 55 180 1.4E-31 T 12-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily VAPA_1c53600 177d627ba9896d5fe950930963eacb41 723 Pfam PF07715 TonB-dependent Receptor Plug Domain 58 170 3.4E-21 T 12-10-2018 IPR012910 TonB-dependent receptor, plug domain VAPA_1c53600 177d627ba9896d5fe950930963eacb41 723 Gene3D G3DSA:2.40.170.20 185 723 1.2E-110 T 12-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily VAPA_1c53600 177d627ba9896d5fe950930963eacb41 723 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 58 723 6.0E-96 T 12-10-2018 IPR010105 TonB-dependent siderophore receptor GO:0005506|GO:0015891|GO:0038023 VAPA_1c20690 874f0210eee1f161b9795a06ae0971ab 316 SUPERFAMILY SSF53697 11 286 8.68E-58 T 12-10-2018 VAPA_1c20690 874f0210eee1f161b9795a06ae0971ab 316 Pfam PF00571 CBS domain 270 314 3.0E-8 T 12-10-2018 IPR000644 CBS domain VAPA_1c20690 874f0210eee1f161b9795a06ae0971ab 316 SUPERFAMILY SSF54631 263 314 1.34E-8 T 12-10-2018 VAPA_1c20690 874f0210eee1f161b9795a06ae0971ab 316 Pfam PF01380 SIS domain 45 175 5.9E-30 T 12-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 VAPA_1c20690 874f0210eee1f161b9795a06ae0971ab 316 PIRSF PIRSF004692 1 316 3.4E-119 T 12-10-2018 IPR004800 Phosphosugar isomerase, KdsD/KpsF-type GO:0005975|GO:0016853 VAPA_1c20690 874f0210eee1f161b9795a06ae0971ab 316 Gene3D G3DSA:3.40.50.10490 8 199 5.6E-64 T 12-10-2018 VAPA_1c20690 874f0210eee1f161b9795a06ae0971ab 316 TIGRFAM TIGR00393 kpsF: sugar isomerase, KpsF/GutQ family 49 314 7.4E-98 T 12-10-2018 IPR004800 Phosphosugar isomerase, KdsD/KpsF-type GO:0005975|GO:0016853 VAPA_1c20690 874f0210eee1f161b9795a06ae0971ab 316 Gene3D G3DSA:3.10.580.10 200 316 2.1E-28 T 12-10-2018 VAPA_1c14720 ea843ef5ca587d092cf280422e410a81 365 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 41 346 4.3E-72 T 12-10-2018 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 VAPA_1c14720 ea843ef5ca587d092cf280422e410a81 365 SUPERFAMILY SSF55120 111 347 1.47E-61 T 12-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 VAPA_1c14720 ea843ef5ca587d092cf280422e410a81 365 SMART SM00363 45 104 3.2E-7 T 12-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VAPA_1c14720 ea843ef5ca587d092cf280422e410a81 365 SUPERFAMILY SSF55174 44 95 4.71E-8 T 12-10-2018 VAPA_1c14720 ea843ef5ca587d092cf280422e410a81 365 Gene3D G3DSA:3.30.2350.10 116 351 3.7E-70 T 12-10-2018 VAPA_1c14720 ea843ef5ca587d092cf280422e410a81 365 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 162 176 - T 12-10-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 VAPA_1c14720 ea843ef5ca587d092cf280422e410a81 365 Pfam PF00849 RNA pseudouridylate synthase 124 287 5.5E-31 T 12-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 VAPA_1c14720 ea843ef5ca587d092cf280422e410a81 365 Gene3D G3DSA:3.10.290.10 33 96 5.0E-14 T 12-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 VAPA_1c14720 ea843ef5ca587d092cf280422e410a81 365 Pfam PF01479 S4 domain 45 91 1.3E-8 T 12-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VAPA_1c27820 83b049bb41310f3d6405158f8c48bab3 372 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 99 136 - T 12-10-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 VAPA_1c27820 83b049bb41310f3d6405158f8c48bab3 372 Pfam PF01546 Peptidase family M20/M25/M40 66 361 5.5E-35 T 12-10-2018 IPR002933 Peptidase M20 GO:0016787 VAPA_1c27820 83b049bb41310f3d6405158f8c48bab3 372 SUPERFAMILY SSF53187 3 361 2.21E-54 T 12-10-2018 VAPA_1c27820 83b049bb41310f3d6405158f8c48bab3 372 Gene3D G3DSA:3.30.70.360 173 282 1.7E-97 T 12-10-2018 VAPA_1c27820 83b049bb41310f3d6405158f8c48bab3 372 TIGRFAM TIGR01892 AcOrn-deacetyl: acetylornithine deacetylase (ArgE) 5 361 6.7E-106 T 12-10-2018 IPR010169 Acetylornithine deacetylase ArgE GO:0005737|GO:0006526|GO:0008777 KEGG: 00220+3.5.1.16|MetaCyc: PWY-5154 VAPA_1c27820 83b049bb41310f3d6405158f8c48bab3 372 SUPERFAMILY SSF55031 175 270 7.92E-23 T 12-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain VAPA_1c27820 83b049bb41310f3d6405158f8c48bab3 372 Pfam PF07687 Peptidase dimerisation domain 170 269 1.2E-19 T 12-10-2018 IPR011650 Peptidase M20, dimerisation domain VAPA_1c27820 83b049bb41310f3d6405158f8c48bab3 372 Gene3D G3DSA:3.40.630.10 10 351 1.7E-97 T 12-10-2018 VAPA_1c18910 aa6fed3e36297cd3fe267986847c2522 70 Pfam PF10636 Hemin uptake protein hemP 35 70 7.8E-15 T 12-10-2018 IPR019600 Hemin uptake protein HemP VAPA_1c18910 aa6fed3e36297cd3fe267986847c2522 70 Gene3D G3DSA:2.10.70.10 32 70 6.4E-12 T 12-10-2018 VAPA_1c08720 c6b72bf4546c42918db232367175f870 144 Pfam PF09917 Uncharacterized protein conserved in bacteria (DUF2147) 25 142 1.3E-26 T 12-10-2018 IPR019223 Domain of unknown function DUF2147 VAPA_1c08720 c6b72bf4546c42918db232367175f870 144 Gene3D G3DSA:2.40.128.520 23 144 4.1E-14 T 12-10-2018 VAPA_1c00010 04267071058a80f1a5831d8131e9bfd3 459 Hamap MF_00377 Chromosomal replication initiator protein DnaA [dnaA]. 8 458 31.092 T 12-10-2018 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 VAPA_1c00010 04267071058a80f1a5831d8131e9bfd3 459 Pfam PF11638 DnaA N-terminal domain 8 70 6.5E-18 T 12-10-2018 IPR024633 DnaA N-terminal domain VAPA_1c00010 04267071058a80f1a5831d8131e9bfd3 459 Gene3D G3DSA:3.30.300.180 8 111 7.5E-24 T 12-10-2018 IPR038454 DnaA, N-terminal domain superfamily VAPA_1c00010 04267071058a80f1a5831d8131e9bfd3 459 SMART SM00760 367 436 7.5E-44 T 12-10-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 VAPA_1c00010 04267071058a80f1a5831d8131e9bfd3 459 TIGRFAM TIGR00362 DnaA: chromosomal replication initiator protein DnaA 11 457 6.3E-168 T 12-10-2018 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 VAPA_1c00010 04267071058a80f1a5831d8131e9bfd3 459 SUPERFAMILY SSF48295 355 458 4.45E-36 T 12-10-2018 IPR010921 Trp repressor/replication initiator GO:0043565 VAPA_1c00010 04267071058a80f1a5831d8131e9bfd3 459 Pfam PF08299 Bacterial dnaA protein helix-turn-helix 368 436 9.3E-33 T 12-10-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 VAPA_1c00010 04267071058a80f1a5831d8131e9bfd3 459 SUPERFAMILY SSF52540 124 335 3.06E-39 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c00010 04267071058a80f1a5831d8131e9bfd3 459 Pfam PF00308 Bacterial dnaA protein 124 341 9.4E-84 T 12-10-2018 IPR013317 Chromosomal replication initiator protein DnaA VAPA_1c00010 04267071058a80f1a5831d8131e9bfd3 459 Gene3D G3DSA:1.10.1750.10 361 458 1.5E-35 T 12-10-2018 IPR010921 Trp repressor/replication initiator GO:0043565 VAPA_1c00010 04267071058a80f1a5831d8131e9bfd3 459 Gene3D G3DSA:1.10.8.60 290 360 1.6E-24 T 12-10-2018 VAPA_1c00010 04267071058a80f1a5831d8131e9bfd3 459 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 189 203 8.9E-48 T 12-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like VAPA_1c00010 04267071058a80f1a5831d8131e9bfd3 459 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 221 235 8.9E-48 T 12-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like VAPA_1c00010 04267071058a80f1a5831d8131e9bfd3 459 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 157 177 8.9E-48 T 12-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like VAPA_1c00010 04267071058a80f1a5831d8131e9bfd3 459 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 417 436 8.9E-48 T 12-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like VAPA_1c00010 04267071058a80f1a5831d8131e9bfd3 459 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 255 282 8.9E-48 T 12-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like VAPA_1c00010 04267071058a80f1a5831d8131e9bfd3 459 SMART SM00382 156 290 1.1E-8 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c00010 04267071058a80f1a5831d8131e9bfd3 459 ProSitePatterns PS01008 DnaA protein signature. 417 436 - T 12-10-2018 IPR018312 Chromosomal replication control, initiator DnaA, conserved site GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 VAPA_1c00010 04267071058a80f1a5831d8131e9bfd3 459 Gene3D G3DSA:3.40.50.300 122 289 3.1E-46 T 12-10-2018 VAPA_2c02400 aa9b02dbc794b15debfd931b8650a665 322 SUPERFAMILY SSF53850 103 281 7.06E-11 T 12-10-2018 VAPA_2c02400 aa9b02dbc794b15debfd931b8650a665 322 PIRSF PIRSF017082 1 321 8.3E-71 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_2c02400 aa9b02dbc794b15debfd931b8650a665 322 Gene3D G3DSA:3.40.190.150 31 312 2.3E-97 T 12-10-2018 VAPA_2c02400 aa9b02dbc794b15debfd931b8650a665 322 Gene3D G3DSA:3.40.190.10 127 247 2.3E-97 T 12-10-2018 VAPA_2c02400 aa9b02dbc794b15debfd931b8650a665 322 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 48 317 2.1E-70 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c34740 48a7e99671b42ff1385822647adb238b 673 Gene3D G3DSA:3.10.620.30 360 498 1.4E-18 T 12-10-2018 VAPA_1c34740 48a7e99671b42ff1385822647adb238b 673 SUPERFAMILY SSF54001 282 608 1.22E-58 T 12-10-2018 IPR038765 Papain-like cysteine peptidase superfamily VAPA_1c34740 48a7e99671b42ff1385822647adb238b 673 Pfam PF11992 Domain of unknown function (DUF3488) 18 336 2.3E-107 T 12-10-2018 IPR021878 Protein of unknown function DUF3488 VAPA_1c34740 48a7e99671b42ff1385822647adb238b 673 SMART SM00460 416 487 1.2E-18 T 12-10-2018 IPR002931 Transglutaminase-like VAPA_1c34740 48a7e99671b42ff1385822647adb238b 673 Pfam PF01841 Transglutaminase-like superfamily 389 485 3.5E-22 T 12-10-2018 IPR002931 Transglutaminase-like VAPA_1c52460 7142126e56614c845fc10729daee28e4 121 TIGRFAM TIGR00060 L18_bact: ribosomal protein uL18 4 121 1.0E-31 T 12-10-2018 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 VAPA_1c52460 7142126e56614c845fc10729daee28e4 121 Gene3D G3DSA:3.30.420.100 2 121 1.2E-37 T 12-10-2018 VAPA_1c52460 7142126e56614c845fc10729daee28e4 121 Hamap MF_01337_B 50S ribosomal protein L18 [rplR]. 3 121 25.027 T 12-10-2018 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 VAPA_1c52460 7142126e56614c845fc10729daee28e4 121 Pfam PF00861 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast 4 121 1.8E-34 T 12-10-2018 IPR005484 Ribosomal protein L18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 VAPA_1c52460 7142126e56614c845fc10729daee28e4 121 SUPERFAMILY SSF53137 4 119 2.18E-44 T 12-10-2018 VAPA_1c25430 001598b2c176f3318cb7241399ddeb72 434 Gene3D G3DSA:3.90.1150.10 17 419 1.6E-169 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 VAPA_1c25430 001598b2c176f3318cb7241399ddeb72 434 Pfam PF00202 Aminotransferase class-III 48 399 7.7E-53 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 VAPA_1c25430 001598b2c176f3318cb7241399ddeb72 434 Gene3D G3DSA:3.40.640.10 85 323 1.6E-169 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 VAPA_1c25430 001598b2c176f3318cb7241399ddeb72 434 SUPERFAMILY SSF53383 24 425 2.02E-96 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase VAPA_2c01780 0d76717fd81c2e78175c7e921afec09d 194 Gene3D G3DSA:3.40.50.360 7 189 1.8E-47 T 12-10-2018 IPR029039 Flavoprotein-like superfamily VAPA_2c01780 0d76717fd81c2e78175c7e921afec09d 194 SUPERFAMILY SSF52218 11 181 6.13E-42 T 12-10-2018 IPR029039 Flavoprotein-like superfamily VAPA_2c01780 0d76717fd81c2e78175c7e921afec09d 194 Pfam PF03358 NADPH-dependent FMN reductase 11 155 7.5E-35 T 12-10-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 VAPA_1c30430 19880b833da67ddce02552cd02834d16 813 ProSitePatterns PS01046 ATP-dependent serine proteases, lon family, serine active site. 680 688 - T 12-10-2018 IPR008268 Peptidase S16, active site GO:0004176|GO:0004252|GO:0006508 VAPA_1c30430 19880b833da67ddce02552cd02834d16 813 Gene3D G3DSA:3.40.50.300 318 494 3.7E-60 T 12-10-2018 VAPA_1c30430 19880b833da67ddce02552cd02834d16 813 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 356 493 1.7E-17 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 VAPA_1c30430 19880b833da67ddce02552cd02834d16 813 SUPERFAMILY SSF52540 317 590 4.94E-48 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c30430 19880b833da67ddce02552cd02834d16 813 PIRSF PIRSF001174 5 779 0.0 T 12-10-2018 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 VAPA_1c30430 19880b833da67ddce02552cd02834d16 813 TIGRFAM TIGR00763 lon: endopeptidase La 15 775 4.3E-293 T 12-10-2018 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 VAPA_1c30430 19880b833da67ddce02552cd02834d16 813 Pfam PF02190 ATP-dependent protease La (LON) substrate-binding domain 14 205 7.6E-43 T 12-10-2018 IPR003111 Lon, substrate-binding domain VAPA_1c30430 19880b833da67ddce02552cd02834d16 813 SMART SM00382 352 496 2.9E-8 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c30430 19880b833da67ddce02552cd02834d16 813 Gene3D G3DSA:3.30.230.10 589 776 1.5E-79 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup VAPA_1c30430 19880b833da67ddce02552cd02834d16 813 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 574 776 4.5E-94 T 12-10-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 VAPA_1c30430 19880b833da67ddce02552cd02834d16 813 Hamap MF_01973 Lon protease [lon]. 14 776 69.805 T 12-10-2018 IPR027543 Lon protease, bacterial GO:0004176|GO:0004252|GO:0005524|GO:0006508|GO:0043565 VAPA_1c30430 19880b833da67ddce02552cd02834d16 813 Gene3D G3DSA:1.20.58.1480 127 250 1.3E-43 T 12-10-2018 VAPA_1c30430 19880b833da67ddce02552cd02834d16 813 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 677 696 1.3E-52 T 12-10-2018 VAPA_1c30430 19880b833da67ddce02552cd02834d16 813 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 599 615 1.3E-52 T 12-10-2018 VAPA_1c30430 19880b833da67ddce02552cd02834d16 813 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 360 379 1.3E-52 T 12-10-2018 VAPA_1c30430 19880b833da67ddce02552cd02834d16 813 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 730 748 1.3E-52 T 12-10-2018 VAPA_1c30430 19880b833da67ddce02552cd02834d16 813 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 707 726 1.3E-52 T 12-10-2018 VAPA_1c30430 19880b833da67ddce02552cd02834d16 813 Gene3D G3DSA:2.30.130.40 5 121 1.2E-34 T 12-10-2018 VAPA_1c30430 19880b833da67ddce02552cd02834d16 813 Gene3D G3DSA:1.10.8.60 495 588 3.7E-30 T 12-10-2018 VAPA_1c30430 19880b833da67ddce02552cd02834d16 813 SUPERFAMILY SSF54211 599 774 5.69E-58 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold VAPA_1c30430 19880b833da67ddce02552cd02834d16 813 SUPERFAMILY SSF88697 13 206 7.7E-52 T 12-10-2018 IPR015947 PUA-like superfamily VAPA_1c30430 19880b833da67ddce02552cd02834d16 813 SMART SM00464 13 207 1.1E-73 T 12-10-2018 IPR003111 Lon, substrate-binding domain VAPA_1c12500 270855e7394eaf070d70a509e3f9ed96 750 Gene3D G3DSA:3.40.50.300 466 747 2.5E-71 T 12-10-2018 VAPA_1c12500 270855e7394eaf070d70a509e3f9ed96 750 TIGRFAM TIGR01005 eps_transp_fam: exopolysaccharide transport protein family 23 747 6.1E-149 T 12-10-2018 IPR005700 Exopolysaccharide biosynthesis protein ExoP-like GO:0045226 VAPA_1c12500 270855e7394eaf070d70a509e3f9ed96 750 Pfam PF13614 AAA domain 558 671 9.2E-13 T 12-10-2018 IPR025669 AAA domain VAPA_1c12500 270855e7394eaf070d70a509e3f9ed96 750 SUPERFAMILY SSF52540 548 727 4.84E-37 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c12500 270855e7394eaf070d70a509e3f9ed96 750 Pfam PF13807 G-rich domain on putative tyrosine kinase 392 471 6.5E-28 T 12-10-2018 IPR032807 Tyrosine kinase, G-rich domain VAPA_1c12500 270855e7394eaf070d70a509e3f9ed96 750 Pfam PF02706 Chain length determinant protein 21 111 1.5E-14 T 12-10-2018 IPR003856 Polysaccharide chain length determinant N-terminal domain GO:0009103|GO:0016020 VAPA_1c12500 270855e7394eaf070d70a509e3f9ed96 750 TIGRFAM TIGR01007 eps_fam: capsular exopolysaccharide family 529 733 3.3E-47 T 12-10-2018 IPR005702 Exopolysaccharide synthesis protein GO:0045226 VAPA_2c00710 756fe4246694a25d3513a4a916c1d8b2 181 SUPERFAMILY SSF51182 2 179 2.22E-76 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily VAPA_2c00710 756fe4246694a25d3513a4a916c1d8b2 181 TIGRFAM TIGR01221 rmlC: dTDP-4-dehydrorhamnose 3,5-epimerase 3 178 6.9E-81 T 12-10-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 VAPA_2c00710 756fe4246694a25d3513a4a916c1d8b2 181 Pfam PF00908 dTDP-4-dehydrorhamnose 3,5-epimerase 6 176 2.2E-74 T 12-10-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 VAPA_2c00710 756fe4246694a25d3513a4a916c1d8b2 181 Gene3D G3DSA:2.60.120.10 4 180 1.2E-73 T 12-10-2018 IPR014710 RmlC-like jelly roll fold VAPA_2c00710 756fe4246694a25d3513a4a916c1d8b2 181 ProDom PD001462 35-EPIMERASE DTDP-4-DEHYDRORHAMNOSE ISOMERASE RMLC EPIMERASE RELATED DTDP-6-DEOXY-D-GLUCOSE-35-EPIMERASE DTDP-4-KETO-6-DEOXY-D-GLUCOSE DTDP-4-KETO-6-DEOXYGLUCOSE-35-EPIMERASE DTDP-L-RHAMNOSE 4 180 7.0E-76 T 12-10-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 VAPA_1c07120 d2340f55d7c3f128205d4b5282fcdbb5 326 SUPERFAMILY SSF53850 115 284 1.85E-11 T 12-10-2018 VAPA_1c07120 d2340f55d7c3f128205d4b5282fcdbb5 326 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 51 322 3.6E-81 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c07120 d2340f55d7c3f128205d4b5282fcdbb5 326 Gene3D G3DSA:3.40.190.150 31 316 1.2E-107 T 12-10-2018 VAPA_1c07120 d2340f55d7c3f128205d4b5282fcdbb5 326 Gene3D G3DSA:3.40.190.10 128 251 1.2E-107 T 12-10-2018 VAPA_1c07120 d2340f55d7c3f128205d4b5282fcdbb5 326 PIRSF PIRSF017082 1 326 4.2E-81 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c37190 f13c2139386a6b926d335f0911e8f0cb 782 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 731 739 - T 12-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 VAPA_1c37190 f13c2139386a6b926d335f0911e8f0cb 782 SUPERFAMILY SSF63380 469 564 2.33E-26 T 12-10-2018 IPR017938 Riboflavin synthase-like beta-barrel VAPA_1c37190 f13c2139386a6b926d335f0911e8f0cb 782 Gene3D G3DSA:3.40.50.80 566 682 4.5E-23 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain VAPA_1c37190 f13c2139386a6b926d335f0911e8f0cb 782 PRINTS PR00359 B-class P450 signature 329 356 2.8E-31 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 VAPA_1c37190 f13c2139386a6b926d335f0911e8f0cb 782 PRINTS PR00359 B-class P450 signature 357 372 2.8E-31 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 VAPA_1c37190 f13c2139386a6b926d335f0911e8f0cb 782 PRINTS PR00359 B-class P450 signature 388 399 2.8E-31 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 VAPA_1c37190 f13c2139386a6b926d335f0911e8f0cb 782 PRINTS PR00359 B-class P450 signature 169 185 2.8E-31 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 VAPA_1c37190 f13c2139386a6b926d335f0911e8f0cb 782 PRINTS PR00359 B-class P450 signature 379 388 2.8E-31 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 VAPA_1c37190 f13c2139386a6b926d335f0911e8f0cb 782 PRINTS PR00359 B-class P450 signature 186 201 2.8E-31 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 VAPA_1c37190 f13c2139386a6b926d335f0911e8f0cb 782 PRINTS PR00359 B-class P450 signature 123 134 2.8E-31 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 VAPA_1c37190 f13c2139386a6b926d335f0911e8f0cb 782 PRINTS PR00359 B-class P450 signature 312 323 2.8E-31 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 VAPA_1c37190 f13c2139386a6b926d335f0911e8f0cb 782 SUPERFAMILY SSF54292 672 782 2.1E-26 T 12-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 VAPA_1c37190 f13c2139386a6b926d335f0911e8f0cb 782 Pfam PF00067 Cytochrome P450 311 408 6.5E-18 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 VAPA_1c37190 f13c2139386a6b926d335f0911e8f0cb 782 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 381 390 - T 12-10-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 VAPA_1c37190 f13c2139386a6b926d335f0911e8f0cb 782 Pfam PF00970 Oxidoreductase FAD-binding domain 472 566 9.5E-6 T 12-10-2018 IPR008333 Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain Reactome: R-HSA-1237044 VAPA_1c37190 f13c2139386a6b926d335f0911e8f0cb 782 SUPERFAMILY SSF48264 43 439 5.63E-87 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 VAPA_1c37190 f13c2139386a6b926d335f0911e8f0cb 782 Gene3D G3DSA:3.10.20.30 687 782 8.0E-24 T 12-10-2018 IPR012675 Beta-grasp domain superfamily VAPA_1c37190 f13c2139386a6b926d335f0911e8f0cb 782 Gene3D G3DSA:2.40.30.10 463 565 1.7E-27 T 12-10-2018 VAPA_1c37190 f13c2139386a6b926d335f0911e8f0cb 782 SUPERFAMILY SSF52343 565 680 3.4E-25 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain VAPA_1c37190 f13c2139386a6b926d335f0911e8f0cb 782 Gene3D G3DSA:1.10.630.10 9 449 5.3E-108 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 VAPA_1c37190 f13c2139386a6b926d335f0911e8f0cb 782 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 703 773 8.9E-12 T 12-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 VAPA_1c25690 e257338e2d21d51a31d015038ff51f86 304 SMART SM00460 176 251 1.9E-18 T 12-10-2018 IPR002931 Transglutaminase-like VAPA_1c25690 e257338e2d21d51a31d015038ff51f86 304 Gene3D G3DSA:3.10.620.30 91 291 1.6E-37 T 12-10-2018 VAPA_1c25690 e257338e2d21d51a31d015038ff51f86 304 Pfam PF08379 Bacterial transglutaminase-like N-terminal region 5 83 2.2E-17 T 12-10-2018 IPR013589 Bacterial transglutaminase-like, N-terminal VAPA_1c25690 e257338e2d21d51a31d015038ff51f86 304 Pfam PF01841 Transglutaminase-like superfamily 144 249 2.2E-19 T 12-10-2018 IPR002931 Transglutaminase-like VAPA_1c25690 e257338e2d21d51a31d015038ff51f86 304 SUPERFAMILY SSF54001 9 281 1.54E-38 T 12-10-2018 IPR038765 Papain-like cysteine peptidase superfamily VAPA_1c41250 bbc61e568b386786c94eb3a675af42e8 531 Gene3D G3DSA:3.40.250.10 372 471 2.4E-13 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily VAPA_1c41250 bbc61e568b386786c94eb3a675af42e8 531 Gene3D G3DSA:3.40.250.10 6 112 1.1E-17 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily VAPA_1c41250 bbc61e568b386786c94eb3a675af42e8 531 Gene3D G3DSA:3.40.250.10 263 352 7.5E-19 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily VAPA_1c41250 bbc61e568b386786c94eb3a675af42e8 531 SUPERFAMILY SSF52821 3 123 2.36E-25 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily VAPA_1c41250 bbc61e568b386786c94eb3a675af42e8 531 SMART SM00450 267 363 2.0E-6 T 12-10-2018 IPR001763 Rhodanese-like domain VAPA_1c41250 bbc61e568b386786c94eb3a675af42e8 531 SMART SM00450 133 231 5.1E-5 T 12-10-2018 IPR001763 Rhodanese-like domain VAPA_1c41250 bbc61e568b386786c94eb3a675af42e8 531 SMART SM00450 374 467 5.1E-4 T 12-10-2018 IPR001763 Rhodanese-like domain VAPA_1c41250 bbc61e568b386786c94eb3a675af42e8 531 SMART SM00450 9 107 1.6E-11 T 12-10-2018 IPR001763 Rhodanese-like domain VAPA_1c41250 bbc61e568b386786c94eb3a675af42e8 531 SUPERFAMILY SSF52821 108 235 7.07E-29 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily VAPA_1c41250 bbc61e568b386786c94eb3a675af42e8 531 SUPERFAMILY SSF52821 371 523 1.57E-22 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily VAPA_1c41250 bbc61e568b386786c94eb3a675af42e8 531 Pfam PF00581 Rhodanese-like domain 280 355 5.1E-8 T 12-10-2018 IPR001763 Rhodanese-like domain VAPA_1c41250 bbc61e568b386786c94eb3a675af42e8 531 Pfam PF00581 Rhodanese-like domain 10 104 9.8E-7 T 12-10-2018 IPR001763 Rhodanese-like domain VAPA_1c41250 bbc61e568b386786c94eb3a675af42e8 531 Pfam PF00581 Rhodanese-like domain 133 227 4.2E-9 T 12-10-2018 IPR001763 Rhodanese-like domain VAPA_1c41250 bbc61e568b386786c94eb3a675af42e8 531 Pfam PF00581 Rhodanese-like domain 377 462 1.6E-4 T 12-10-2018 IPR001763 Rhodanese-like domain VAPA_1c41250 bbc61e568b386786c94eb3a675af42e8 531 Gene3D G3DSA:3.40.250.10 129 236 1.0E-20 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily VAPA_1c41250 bbc61e568b386786c94eb3a675af42e8 531 SUPERFAMILY SSF52821 256 355 7.33E-23 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily VAPA_2c04570 4acc6c521e7050b9a3b7ee5a7763e935 219 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 23 194 1.2E-34 T 12-10-2018 IPR003740 Uncharacterised membrane protein YitT VAPA_2c10190 5f8febf63bcfb1524dfd4be8ad01e1ce 784 SUPERFAMILY SSF101967 138 260 7.32E-13 T 12-10-2018 VAPA_2c10190 5f8febf63bcfb1524dfd4be8ad01e1ce 784 SUPERFAMILY SSF101967 629 686 9.02E-5 T 12-10-2018 VAPA_2c10190 5f8febf63bcfb1524dfd4be8ad01e1ce 784 SUPERFAMILY SSF101967 471 626 1.29E-20 T 12-10-2018 VAPA_2c10190 5f8febf63bcfb1524dfd4be8ad01e1ce 784 Gene3D G3DSA:2.150.10.10 532 649 4.8E-20 T 12-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal VAPA_2c10190 5f8febf63bcfb1524dfd4be8ad01e1ce 784 Gene3D G3DSA:2.150.10.10 461 531 2.5E-17 T 12-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal VAPA_2c10190 5f8febf63bcfb1524dfd4be8ad01e1ce 784 Gene3D G3DSA:2.150.10.10 330 459 4.0E-20 T 12-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal VAPA_2c10190 5f8febf63bcfb1524dfd4be8ad01e1ce 784 Pfam PF05658 Head domain of trimeric autotransporter adhesin 152 178 9.8E-5 T 12-10-2018 IPR008640 Head domain of trimeric autotransporter adhesin GO:0009405|GO:0019867 VAPA_2c10190 5f8febf63bcfb1524dfd4be8ad01e1ce 784 SUPERFAMILY SSF101967 228 451 4.58E-21 T 12-10-2018 VAPA_2c10190 5f8febf63bcfb1524dfd4be8ad01e1ce 784 Gene3D G3DSA:3.30.1300.30 675 783 1.2E-12 T 12-10-2018 VAPA_2c10190 5f8febf63bcfb1524dfd4be8ad01e1ce 784 Pfam PF05662 Coiled stalk of trimeric autotransporter adhesin 666 706 5.4E-7 T 12-10-2018 IPR008635 Coiled stalk of trimeric autotransporter adhesin GO:0009405|GO:0019867 VAPA_2c10190 5f8febf63bcfb1524dfd4be8ad01e1ce 784 Pfam PF05662 Coiled stalk of trimeric autotransporter adhesin 429 464 2.9E-7 T 12-10-2018 IPR008635 Coiled stalk of trimeric autotransporter adhesin GO:0009405|GO:0019867 VAPA_2c10190 5f8febf63bcfb1524dfd4be8ad01e1ce 784 Pfam PF05662 Coiled stalk of trimeric autotransporter adhesin 604 644 1.0E-8 T 12-10-2018 IPR008635 Coiled stalk of trimeric autotransporter adhesin GO:0009405|GO:0019867 VAPA_2c10190 5f8febf63bcfb1524dfd4be8ad01e1ce 784 SUPERFAMILY SSF54523 677 783 4.71E-14 T 12-10-2018 VAPA_2c10190 5f8febf63bcfb1524dfd4be8ad01e1ce 784 Gene3D G3DSA:2.150.10.10 105 222 1.5E-11 T 12-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal VAPA_2c10190 5f8febf63bcfb1524dfd4be8ad01e1ce 784 Gene3D G3DSA:2.150.10.10 223 329 3.4E-10 T 12-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal VAPA_2c10190 5f8febf63bcfb1524dfd4be8ad01e1ce 784 Pfam PF03895 YadA-like membrane anchor domain 724 783 2.8E-6 T 12-10-2018 IPR005594 YadA-like, C-terminal VAPA_1c04270 aa6df2a8ada2778f4e027a444a880d8f 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 1.0E-5 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c04270 aa6df2a8ada2778f4e027a444a880d8f 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 143 151 1.0E-5 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c04270 aa6df2a8ada2778f4e027a444a880d8f 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 164 183 1.0E-5 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c04270 aa6df2a8ada2778f4e027a444a880d8f 259 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 20 256 9.4E-57 T 12-10-2018 VAPA_1c04270 aa6df2a8ada2778f4e027a444a880d8f 259 SUPERFAMILY SSF51735 10 258 2.84E-71 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c04270 aa6df2a8ada2778f4e027a444a880d8f 259 Gene3D G3DSA:3.40.50.720 2 259 1.2E-71 T 12-10-2018 VAPA_1c04270 aa6df2a8ada2778f4e027a444a880d8f 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 185 202 9.2E-37 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c04270 aa6df2a8ada2778f4e027a444a880d8f 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 12 29 9.2E-37 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c04270 aa6df2a8ada2778f4e027a444a880d8f 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 164 183 9.2E-37 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c04270 aa6df2a8ada2778f4e027a444a880d8f 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 9.2E-37 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c04270 aa6df2a8ada2778f4e027a444a880d8f 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 220 240 9.2E-37 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c04270 aa6df2a8ada2778f4e027a444a880d8f 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 137 153 9.2E-37 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c02360 edb952ef6cafd87e14aa4a2f764d1a8b 794 Gene3D G3DSA:2.30.110.50 10 330 3.0E-121 T 12-10-2018 VAPA_1c02360 edb952ef6cafd87e14aa4a2f764d1a8b 794 SUPERFAMILY SSF69279 9 182 1.28E-59 T 12-10-2018 VAPA_1c02360 edb952ef6cafd87e14aa4a2f764d1a8b 794 TIGRFAM TIGR01646 vgr_GE: Rhs element Vgr protein 20 501 2.9E-143 T 12-10-2018 IPR006533 Type VI secretion system, RhsGE-associated Vgr protein VAPA_1c02360 edb952ef6cafd87e14aa4a2f764d1a8b 794 Gene3D G3DSA:2.40.50.230 351 453 5.3E-41 T 12-10-2018 IPR037026 Vgr protein, OB-fold domain superfamily VAPA_1c02360 edb952ef6cafd87e14aa4a2f764d1a8b 794 Gene3D G3DSA:3.30.1920.30 222 284 3.0E-121 T 12-10-2018 VAPA_1c02360 edb952ef6cafd87e14aa4a2f764d1a8b 794 Pfam PF05954 Phage late control gene D protein (GPD) 25 326 2.1E-102 T 12-10-2018 VAPA_1c02360 edb952ef6cafd87e14aa4a2f764d1a8b 794 Gene3D G3DSA:3.55.50.10 96 186 3.0E-121 T 12-10-2018 VAPA_1c02360 edb952ef6cafd87e14aa4a2f764d1a8b 794 TIGRFAM TIGR03361 VI_Rhs_Vgr: type VI secretion system Vgr family protein 7 518 5.4E-179 T 12-10-2018 IPR017847 Type VI secretion system, RhsGE-associated Vgr family subset VAPA_1c02360 edb952ef6cafd87e14aa4a2f764d1a8b 794 SUPERFAMILY SSF69349 439 652 6.98E-29 T 12-10-2018 VAPA_1c02360 edb952ef6cafd87e14aa4a2f764d1a8b 794 SUPERFAMILY SSF69255 362 448 5.23E-31 T 12-10-2018 VAPA_1c02360 edb952ef6cafd87e14aa4a2f764d1a8b 794 SUPERFAMILY SSF69279 186 359 2.55E-44 T 12-10-2018 VAPA_1c20480 1d7cf9ee8057ea39f1cbc10454b09fd2 269 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 147 155 3.7E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c20480 1d7cf9ee8057ea39f1cbc10454b09fd2 269 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 93 104 3.7E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c20480 1d7cf9ee8057ea39f1cbc10454b09fd2 269 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 166 185 3.7E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c20480 1d7cf9ee8057ea39f1cbc10454b09fd2 269 Gene3D G3DSA:3.40.50.720 1 267 2.8E-75 T 12-10-2018 VAPA_1c20480 1d7cf9ee8057ea39f1cbc10454b09fd2 269 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 187 204 4.6E-34 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c20480 1d7cf9ee8057ea39f1cbc10454b09fd2 269 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 166 185 4.6E-34 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c20480 1d7cf9ee8057ea39f1cbc10454b09fd2 269 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 228 248 4.6E-34 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c20480 1d7cf9ee8057ea39f1cbc10454b09fd2 269 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 93 104 4.6E-34 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c20480 1d7cf9ee8057ea39f1cbc10454b09fd2 269 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 19 36 4.6E-34 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c20480 1d7cf9ee8057ea39f1cbc10454b09fd2 269 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 141 157 4.6E-34 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c20480 1d7cf9ee8057ea39f1cbc10454b09fd2 269 SUPERFAMILY SSF51735 10 265 2.55E-73 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c20480 1d7cf9ee8057ea39f1cbc10454b09fd2 269 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 30 264 8.6E-61 T 12-10-2018 VAPA_1c33780 393bd37c2d8298239451a083abc0d707 303 SUPERFAMILY SSF46785 8 120 3.21E-22 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c33780 393bd37c2d8298239451a083abc0d707 303 SUPERFAMILY SSF53850 96 301 6.06E-42 T 12-10-2018 VAPA_1c33780 393bd37c2d8298239451a083abc0d707 303 Gene3D G3DSA:3.40.190.290 101 302 4.0E-40 T 12-10-2018 VAPA_1c33780 393bd37c2d8298239451a083abc0d707 303 Gene3D G3DSA:1.10.10.10 10 100 1.1E-18 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c33780 393bd37c2d8298239451a083abc0d707 303 Pfam PF03466 LysR substrate binding domain 96 300 1.0E-38 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_1c33780 393bd37c2d8298239451a083abc0d707 303 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 15 70 3.0E-16 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c49230 68b634b56c6a804b5e0abbe4717ceda6 264 SMART SM00062 42 264 1.1E-36 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF VAPA_1c49230 68b634b56c6a804b5e0abbe4717ceda6 264 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 43 263 4.5E-39 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF VAPA_1c49230 68b634b56c6a804b5e0abbe4717ceda6 264 Gene3D G3DSA:3.40.190.10 34 253 6.3E-73 T 12-10-2018 VAPA_1c49230 68b634b56c6a804b5e0abbe4717ceda6 264 SUPERFAMILY SSF53850 16 263 3.26E-50 T 12-10-2018 VAPA_1c49230 68b634b56c6a804b5e0abbe4717ceda6 264 Gene3D G3DSA:3.40.190.10 129 220 6.3E-73 T 12-10-2018 VAPA_1c44240 3ab2c6fc9dfb0b916758dd6cfff5aa15 135 Gene3D G3DSA:3.40.50.2300 4 131 1.0E-5 T 12-10-2018 VAPA_1c44240 3ab2c6fc9dfb0b916758dd6cfff5aa15 135 SUPERFAMILY SSF52172 7 108 9.37E-6 T 12-10-2018 IPR011006 CheY-like superfamily VAPA_2c08390 32718c7390de2260a604ed5ca43e4bc0 417 SUPERFAMILY SSF53474 10 237 1.61E-46 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_2c08390 32718c7390de2260a604ed5ca43e4bc0 417 SUPERFAMILY SSF54427 245 389 2.15E-25 T 12-10-2018 IPR032710 NTF2-like domain superfamily VAPA_2c08390 32718c7390de2260a604ed5ca43e4bc0 417 Gene3D G3DSA:3.10.450.50 252 384 1.1E-22 T 12-10-2018 VAPA_2c08390 32718c7390de2260a604ed5ca43e4bc0 417 Pfam PF01738 Dienelactone hydrolase family 24 238 8.1E-50 T 12-10-2018 IPR002925 Dienelactone hydrolase GO:0016787 VAPA_2c08390 32718c7390de2260a604ed5ca43e4bc0 417 Gene3D G3DSA:3.40.50.1820 9 239 7.9E-58 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c05680 e1a33d7c5979d5266485a4996a369cfc 319 Pfam PF00586 AIR synthase related protein, N-terminal domain 24 133 7.1E-26 T 12-10-2018 IPR016188 PurM-like, N-terminal domain VAPA_1c05680 e1a33d7c5979d5266485a4996a369cfc 319 SUPERFAMILY SSF56042 139 302 1.4E-34 T 12-10-2018 IPR036676 PurM-like, C-terminal domain superfamily VAPA_1c05680 e1a33d7c5979d5266485a4996a369cfc 319 PIRSF PIRSF005303 1 318 2.4E-78 T 12-10-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 VAPA_1c05680 e1a33d7c5979d5266485a4996a369cfc 319 SUPERFAMILY SSF55326 1 133 1.47E-34 T 12-10-2018 IPR036921 PurM-like, N-terminal domain superfamily VAPA_1c05680 e1a33d7c5979d5266485a4996a369cfc 319 Pfam PF02769 AIR synthase related protein, C-terminal domain 146 301 2.2E-9 T 12-10-2018 IPR010918 PurM-like, C-terminal domain VAPA_1c05680 e1a33d7c5979d5266485a4996a369cfc 319 Gene3D G3DSA:3.90.650.10 140 319 5.2E-50 T 12-10-2018 IPR036676 PurM-like, C-terminal domain superfamily VAPA_1c05680 e1a33d7c5979d5266485a4996a369cfc 319 TIGRFAM TIGR01379 thiL: thiamine-phosphate kinase 2 318 3.8E-96 T 12-10-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 VAPA_1c05680 e1a33d7c5979d5266485a4996a369cfc 319 Gene3D G3DSA:3.30.1330.10 1 139 1.1E-48 T 12-10-2018 IPR036921 PurM-like, N-terminal domain superfamily VAPA_1c05680 e1a33d7c5979d5266485a4996a369cfc 319 Hamap MF_02128 Thiamine-monophosphate kinase [thiL]. 1 318 26.486 T 12-10-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 VAPA_1c15440 dc39925a62c6bb5d1e29ab8488819a3d 311 SUPERFAMILY SSF53671 9 307 3.4E-101 T 12-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 VAPA_1c15440 dc39925a62c6bb5d1e29ab8488819a3d 311 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 56 63 - T 12-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 VAPA_1c15440 dc39925a62c6bb5d1e29ab8488819a3d 311 Gene3D G3DSA:3.40.50.1370 146 294 4.7E-64 T 12-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 VAPA_1c15440 dc39925a62c6bb5d1e29ab8488819a3d 311 TIGRFAM TIGR00658 orni_carb_tr: ornithine carbamoyltransferase 11 307 4.0E-112 T 12-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 VAPA_1c15440 dc39925a62c6bb5d1e29ab8488819a3d 311 Hamap MF_01109 Ornithine carbamoyltransferase, catabolic [argI]. 10 308 76.624 T 12-10-2018 IPR024904 Ornithine carbamoyltransferase GO:0004585|GO:0006591 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 VAPA_1c15440 dc39925a62c6bb5d1e29ab8488819a3d 311 Gene3D G3DSA:3.40.50.1370 2 145 1.2E-47 T 12-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 VAPA_1c15440 dc39925a62c6bb5d1e29ab8488819a3d 311 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 157 305 1.9E-50 T 12-10-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 VAPA_1c15440 dc39925a62c6bb5d1e29ab8488819a3d 311 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 138 149 2.1E-27 T 12-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 VAPA_1c15440 dc39925a62c6bb5d1e29ab8488819a3d 311 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 260 269 2.1E-27 T 12-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 VAPA_1c15440 dc39925a62c6bb5d1e29ab8488819a3d 311 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 272 295 2.1E-27 T 12-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 VAPA_1c15440 dc39925a62c6bb5d1e29ab8488819a3d 311 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 56 75 2.1E-27 T 12-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 VAPA_1c15440 dc39925a62c6bb5d1e29ab8488819a3d 311 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 11 150 1.5E-46 T 12-10-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 VAPA_1c15440 dc39925a62c6bb5d1e29ab8488819a3d 311 PRINTS PR00102 Ornithine carbamoyltransferase signature 54 68 3.9E-29 T 12-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 VAPA_1c15440 dc39925a62c6bb5d1e29ab8488819a3d 311 PRINTS PR00102 Ornithine carbamoyltransferase signature 286 297 3.9E-29 T 12-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 VAPA_1c15440 dc39925a62c6bb5d1e29ab8488819a3d 311 PRINTS PR00102 Ornithine carbamoyltransferase signature 127 141 3.9E-29 T 12-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 VAPA_1c15440 dc39925a62c6bb5d1e29ab8488819a3d 311 PRINTS PR00102 Ornithine carbamoyltransferase signature 224 234 3.9E-29 T 12-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 VAPA_1c15440 dc39925a62c6bb5d1e29ab8488819a3d 311 PRINTS PR00102 Ornithine carbamoyltransferase signature 87 100 3.9E-29 T 12-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 VAPA_1c52100 db48e2e567c5b51911589ee3fafa8aeb 427 SUPERFAMILY SSF55781 99 228 2.33E-5 T 12-10-2018 VAPA_1c52100 db48e2e567c5b51911589ee3fafa8aeb 427 Gene3D G3DSA:3.30.450.40 37 222 5.4E-40 T 12-10-2018 IPR029016 GAF-like domain superfamily VAPA_1c52100 db48e2e567c5b51911589ee3fafa8aeb 427 Pfam PF02954 Bacterial regulatory protein, Fis family 375 414 2.3E-13 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 VAPA_1c52100 db48e2e567c5b51911589ee3fafa8aeb 427 SUPERFAMILY SSF46689 365 415 7.53E-12 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 VAPA_1c52100 db48e2e567c5b51911589ee3fafa8aeb 427 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 398 418 1.5E-8 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 VAPA_1c52100 db48e2e567c5b51911589ee3fafa8aeb 427 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 381 398 1.5E-8 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 VAPA_1c52100 db48e2e567c5b51911589ee3fafa8aeb 427 Gene3D G3DSA:1.10.10.60 364 414 2.5E-13 T 12-10-2018 VAPA_2c07580 094c8a463300dce8b0a3230981d6a10f 123 Pfam PF00072 Response regulator receiver domain 6 114 3.1E-12 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_2c07580 094c8a463300dce8b0a3230981d6a10f 123 SMART SM00448 3 117 1.3E-13 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_2c07580 094c8a463300dce8b0a3230981d6a10f 123 Gene3D G3DSA:3.40.50.2300 3 122 7.3E-18 T 12-10-2018 VAPA_2c07580 094c8a463300dce8b0a3230981d6a10f 123 SUPERFAMILY SSF52172 3 118 4.13E-19 T 12-10-2018 IPR011006 CheY-like superfamily VAPA_1c44650 4a7b3c2323ca97fdeff881188e01850c 109 Pfam PF08765 Mor transcription activator family 27 96 3.3E-15 T 12-10-2018 IPR014875 Mor transcription activator VAPA_1c44650 4a7b3c2323ca97fdeff881188e01850c 109 Gene3D G3DSA:1.10.10.60 54 101 1.1E-5 T 12-10-2018 VAPA_1c44650 4a7b3c2323ca97fdeff881188e01850c 109 SUPERFAMILY SSF46689 25 96 7.53E-15 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 VAPA_2c01110 1bc7370301240dd144a4ac4aaf51c773 397 Pfam PF00108 Thiolase, N-terminal domain 8 228 5.7E-15 T 12-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 VAPA_2c01110 1bc7370301240dd144a4ac4aaf51c773 397 PIRSF PIRSF000429 2 396 3.0E-62 T 12-10-2018 IPR002155 Thiolase GO:0016747 VAPA_2c01110 1bc7370301240dd144a4ac4aaf51c773 397 ProSitePatterns PS00737 Thiolases signature 2. 336 352 - T 12-10-2018 IPR020613 Thiolase, conserved site GO:0016747 VAPA_2c01110 1bc7370301240dd144a4ac4aaf51c773 397 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 81 99 - T 12-10-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0016747 VAPA_2c01110 1bc7370301240dd144a4ac4aaf51c773 397 Pfam PF02803 Thiolase, C-terminal domain 273 372 1.3E-10 T 12-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 VAPA_2c01110 1bc7370301240dd144a4ac4aaf51c773 397 Gene3D G3DSA:3.40.47.10 7 396 1.5E-118 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 VAPA_2c01110 1bc7370301240dd144a4ac4aaf51c773 397 SUPERFAMILY SSF53901 23 394 2.82E-46 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 VAPA_2c11540 36ab9fad9a64fa5abe4efb267996ff01 172 TIGRFAM TIGR03293 PhnG_redo: phosphonate C-P lyase system protein PhnG 15 160 1.6E-46 T 12-10-2018 IPR009609 Phosphonate metabolism PhnG GO:0015716|GO:0019634 KEGG: 00440+2.7.8.37|MetaCyc: PWY-7399|MetaCyc: PWY-7805|MetaCyc: PWY-7807 VAPA_2c11540 36ab9fad9a64fa5abe4efb267996ff01 172 Pfam PF06754 Phosphonate metabolism protein PhnG 15 159 5.1E-49 T 12-10-2018 IPR009609 Phosphonate metabolism PhnG GO:0015716|GO:0019634 KEGG: 00440+2.7.8.37|MetaCyc: PWY-7399|MetaCyc: PWY-7805|MetaCyc: PWY-7807 VAPA_1c45900 2049d66111e66ceefbf208a965335ddf 547 SUPERFAMILY SSF54292 261 346 3.28E-22 T 12-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 VAPA_1c45900 2049d66111e66ceefbf208a965335ddf 547 Pfam PF00211 Adenylate and Guanylate cyclase catalytic domain 364 539 6.6E-16 T 12-10-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 VAPA_1c45900 2049d66111e66ceefbf208a965335ddf 547 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 263 336 8.5E-10 T 12-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 VAPA_1c45900 2049d66111e66ceefbf208a965335ddf 547 SMART SM00044 319 526 5.4E-4 T 12-10-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 VAPA_1c45900 2049d66111e66ceefbf208a965335ddf 547 SUPERFAMILY SSF81343 6 209 6.32E-16 T 12-10-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 VAPA_1c45900 2049d66111e66ceefbf208a965335ddf 547 SUPERFAMILY SSF55073 362 543 6.91E-36 T 12-10-2018 IPR029787 Nucleotide cyclase VAPA_1c45900 2049d66111e66ceefbf208a965335ddf 547 Gene3D G3DSA:3.10.20.30 255 349 1.9E-18 T 12-10-2018 IPR012675 Beta-grasp domain superfamily VAPA_1c45900 2049d66111e66ceefbf208a965335ddf 547 Gene3D G3DSA:3.30.70.1230 358 547 1.1E-35 T 12-10-2018 IPR029787 Nucleotide cyclase VAPA_2c02910 738e67f5dbe138dccfda942176b10bf5 245 Gene3D G3DSA:1.10.10.10 11 82 5.8E-17 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_2c02910 738e67f5dbe138dccfda942176b10bf5 245 SMART SM00345 20 79 6.0E-12 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_2c02910 738e67f5dbe138dccfda942176b10bf5 245 Pfam PF00392 Bacterial regulatory proteins, gntR family 16 76 1.2E-15 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_2c02910 738e67f5dbe138dccfda942176b10bf5 245 SUPERFAMILY SSF46785 9 81 6.25E-16 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_2c02910 738e67f5dbe138dccfda942176b10bf5 245 SMART SM00895 105 230 1.1E-20 T 12-10-2018 IPR011711 GntR, C-terminal VAPA_2c02910 738e67f5dbe138dccfda942176b10bf5 245 Pfam PF07729 FCD domain 105 230 2.0E-22 T 12-10-2018 IPR011711 GntR, C-terminal VAPA_2c02910 738e67f5dbe138dccfda942176b10bf5 245 Gene3D G3DSA:1.20.120.530 87 238 5.4E-27 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal VAPA_2c02910 738e67f5dbe138dccfda942176b10bf5 245 SUPERFAMILY SSF48008 102 236 1.91E-23 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal VAPA_2c02910 738e67f5dbe138dccfda942176b10bf5 245 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 53 69 3.1E-8 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_2c02910 738e67f5dbe138dccfda942176b10bf5 245 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 39 53 3.1E-8 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_1c33950 98ac5bc64c854276d137b151bbcd4812 450 SMART SM00388 237 299 9.2E-10 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 VAPA_1c33950 98ac5bc64c854276d137b151bbcd4812 450 Pfam PF08521 Two-component sensor kinase N-terminal 28 158 1.5E-7 T 12-10-2018 IPR013727 Two-component sensor kinase, N-terminal VAPA_1c33950 98ac5bc64c854276d137b151bbcd4812 450 SUPERFAMILY SSF55874 289 436 1.31E-23 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_1c33950 98ac5bc64c854276d137b151bbcd4812 450 Gene3D G3DSA:3.30.565.10 302 448 1.4E-20 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_1c33950 98ac5bc64c854276d137b151bbcd4812 450 SMART SM00387 344 449 2.0E-19 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase VAPA_1c33950 98ac5bc64c854276d137b151bbcd4812 450 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 344 436 2.0E-11 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase VAPA_1c33950 98ac5bc64c854276d137b151bbcd4812 450 Gene3D G3DSA:1.10.287.130 187 300 1.5E-13 T 12-10-2018 VAPA_1c33950 98ac5bc64c854276d137b151bbcd4812 450 PRINTS PR00344 Bacterial sensor protein C-terminal signature 377 391 6.1E-6 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c33950 98ac5bc64c854276d137b151bbcd4812 450 PRINTS PR00344 Bacterial sensor protein C-terminal signature 408 426 6.1E-6 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c33950 98ac5bc64c854276d137b151bbcd4812 450 SUPERFAMILY SSF47384 223 299 2.75E-11 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 VAPA_1c33950 98ac5bc64c854276d137b151bbcd4812 450 Pfam PF00512 His Kinase A (phospho-acceptor) domain 239 299 3.9E-8 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 VAPA_1c43720 1f6d039f3394554f0c85c33bba9315d5 379 PRINTS PR00474 Glutamate 5-kinase family signature 51 65 4.3E-47 T 12-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 VAPA_1c43720 1f6d039f3394554f0c85c33bba9315d5 379 PRINTS PR00474 Glutamate 5-kinase family signature 125 146 4.3E-47 T 12-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 VAPA_1c43720 1f6d039f3394554f0c85c33bba9315d5 379 PRINTS PR00474 Glutamate 5-kinase family signature 157 184 4.3E-47 T 12-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 VAPA_1c43720 1f6d039f3394554f0c85c33bba9315d5 379 PRINTS PR00474 Glutamate 5-kinase family signature 218 238 4.3E-47 T 12-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 VAPA_1c43720 1f6d039f3394554f0c85c33bba9315d5 379 PRINTS PR00474 Glutamate 5-kinase family signature 85 113 4.3E-47 T 12-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 VAPA_1c43720 1f6d039f3394554f0c85c33bba9315d5 379 ProSitePatterns PS00902 Glutamate 5-kinase signature. 216 233 - T 12-10-2018 IPR019797 Glutamate 5-kinase, conserved site GO:0004349|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 VAPA_1c43720 1f6d039f3394554f0c85c33bba9315d5 379 Pfam PF01472 PUA domain 286 360 1.3E-18 T 12-10-2018 IPR002478 PUA domain GO:0003723 VAPA_1c43720 1f6d039f3394554f0c85c33bba9315d5 379 PIRSF PIRSF000729 9 378 3.2E-126 T 12-10-2018 IPR011529 Glutamate 5-kinase GO:0004349|GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922 VAPA_1c43720 1f6d039f3394554f0c85c33bba9315d5 379 SUPERFAMILY SSF53633 14 265 5.89E-69 T 12-10-2018 IPR036393 Acetylglutamate kinase-like superfamily VAPA_1c43720 1f6d039f3394554f0c85c33bba9315d5 379 SUPERFAMILY SSF88697 286 376 3.48E-22 T 12-10-2018 IPR015947 PUA-like superfamily VAPA_1c43720 1f6d039f3394554f0c85c33bba9315d5 379 Hamap MF_00456 Glutamate 5-kinase [proB]. 14 268 35.237 T 12-10-2018 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 VAPA_1c43720 1f6d039f3394554f0c85c33bba9315d5 379 SMART SM00359 286 365 3.5E-11 T 12-10-2018 IPR002478 PUA domain GO:0003723 VAPA_1c43720 1f6d039f3394554f0c85c33bba9315d5 379 Gene3D G3DSA:2.30.130.10 275 377 6.0E-30 T 12-10-2018 IPR036974 PUA domain superfamily GO:0003723 VAPA_1c43720 1f6d039f3394554f0c85c33bba9315d5 379 Gene3D G3DSA:3.40.1160.10 5 274 3.1E-91 T 12-10-2018 IPR036393 Acetylglutamate kinase-like superfamily VAPA_1c43720 1f6d039f3394554f0c85c33bba9315d5 379 Pfam PF00696 Amino acid kinase family 15 242 9.8E-43 T 12-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 VAPA_1c43720 1f6d039f3394554f0c85c33bba9315d5 379 TIGRFAM TIGR01027 proB: glutamate 5-kinase 14 376 1.7E-126 T 12-10-2018 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 VAPA_1c52920 720c7afb0ab97ef46576126689848934 397 Gene3D G3DSA:3.40.50.1260 15 391 1.5E-144 T 12-10-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 VAPA_1c52920 720c7afb0ab97ef46576126689848934 397 ProSitePatterns PS00111 Phosphoglycerate kinase signature. 19 29 - T 12-10-2018 IPR015911 Phosphoglycerate kinase, conserved site GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 VAPA_1c52920 720c7afb0ab97ef46576126689848934 397 PIRSF PIRSF000724 2 396 1.2E-133 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 VAPA_1c52920 720c7afb0ab97ef46576126689848934 397 Hamap MF_00145 Phosphoglycerate kinase [pgk]. 8 393 38.476 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 VAPA_1c52920 720c7afb0ab97ef46576126689848934 397 SUPERFAMILY SSF53748 15 393 2.0E-137 T 12-10-2018 IPR036043 Phosphoglycerate kinase superfamily GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 VAPA_1c52920 720c7afb0ab97ef46576126689848934 397 Gene3D G3DSA:3.40.50.1260 170 383 1.5E-144 T 12-10-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 VAPA_1c52920 720c7afb0ab97ef46576126689848934 397 Pfam PF00162 Phosphoglycerate kinase 15 383 2.5E-138 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 VAPA_1c52920 720c7afb0ab97ef46576126689848934 397 PRINTS PR00477 Phosphoglycerate kinase family signature 137 159 3.4E-78 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 VAPA_1c52920 720c7afb0ab97ef46576126689848934 397 PRINTS PR00477 Phosphoglycerate kinase family signature 369 386 3.4E-78 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 VAPA_1c52920 720c7afb0ab97ef46576126689848934 397 PRINTS PR00477 Phosphoglycerate kinase family signature 14 30 3.4E-78 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 VAPA_1c52920 720c7afb0ab97ef46576126689848934 397 PRINTS PR00477 Phosphoglycerate kinase family signature 109 124 3.4E-78 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 VAPA_1c52920 720c7afb0ab97ef46576126689848934 397 PRINTS PR00477 Phosphoglycerate kinase family signature 36 58 3.4E-78 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 VAPA_1c52920 720c7afb0ab97ef46576126689848934 397 PRINTS PR00477 Phosphoglycerate kinase family signature 168 190 3.4E-78 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 VAPA_1c52920 720c7afb0ab97ef46576126689848934 397 PRINTS PR00477 Phosphoglycerate kinase family signature 313 338 3.4E-78 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 VAPA_1c52920 720c7afb0ab97ef46576126689848934 397 PRINTS PR00477 Phosphoglycerate kinase family signature 191 210 3.4E-78 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 VAPA_1c52920 720c7afb0ab97ef46576126689848934 397 PRINTS PR00477 Phosphoglycerate kinase family signature 346 357 3.4E-78 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 VAPA_1c38310 ad2cbde4063a076fec50b60a34edb309 242 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 150 166 1.1E-7 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 VAPA_1c38310 ad2cbde4063a076fec50b60a34edb309 242 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 10 21 1.1E-7 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 VAPA_1c38310 ad2cbde4063a076fec50b60a34edb309 242 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 195 208 1.1E-7 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 VAPA_1c38310 ad2cbde4063a076fec50b60a34edb309 242 TIGRFAM TIGR01428 HAD_type_II: haloacid dehalogenase, type II 11 211 8.3E-46 T 12-10-2018 IPR006328 L-2-Haloacid dehalogenase GO:0019120 KEGG: 00361+3.8.1.2|KEGG: 00625+3.8.1.2|MetaCyc: PWY-7425 VAPA_1c38310 ad2cbde4063a076fec50b60a34edb309 242 SUPERFAMILY SSF56784 10 240 3.18E-33 T 12-10-2018 IPR036412 HAD-like superfamily VAPA_1c38310 ad2cbde4063a076fec50b60a34edb309 242 Gene3D G3DSA:1.10.150.240 38 108 1.2E-74 T 12-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 VAPA_1c38310 ad2cbde4063a076fec50b60a34edb309 242 TIGRFAM TIGR01493 HAD-SF-IA-v2: HAD hydrolase, family IA, variant 2 13 197 1.4E-17 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 VAPA_1c38310 ad2cbde4063a076fec50b60a34edb309 242 Gene3D G3DSA:3.40.50.1000 11 225 1.2E-74 T 12-10-2018 IPR023214 HAD superfamily VAPA_1c19550 f2cfe71525bcdffc75576896ed66ef22 257 Gene3D G3DSA:1.10.3720.10 52 246 1.5E-30 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c19550 f2cfe71525bcdffc75576896ed66ef22 257 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 77 244 2.2E-30 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 VAPA_1c19550 f2cfe71525bcdffc75576896ed66ef22 257 SUPERFAMILY SSF161098 52 235 2.75E-34 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c37350 7f0eff88031050886fbbd788781c0c6e 282 Pfam PF00072 Response regulator receiver domain 6 120 1.2E-17 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_1c37350 7f0eff88031050886fbbd788781c0c6e 282 SMART SM00448 3 120 3.3E-21 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_1c37350 7f0eff88031050886fbbd788781c0c6e 282 Pfam PF04397 LytTr DNA-binding domain 188 281 1.4E-23 T 12-10-2018 IPR007492 LytTR DNA-binding domain GO:0003677 VAPA_1c37350 7f0eff88031050886fbbd788781c0c6e 282 Gene3D G3DSA:3.40.50.2300 2 139 3.1E-25 T 12-10-2018 VAPA_1c37350 7f0eff88031050886fbbd788781c0c6e 282 Gene3D G3DSA:2.40.50.40 184 245 1.2E-8 T 12-10-2018 VAPA_1c37350 7f0eff88031050886fbbd788781c0c6e 282 SMART SM00850 186 282 4.5E-24 T 12-10-2018 IPR007492 LytTR DNA-binding domain GO:0003677 VAPA_1c37350 7f0eff88031050886fbbd788781c0c6e 282 SUPERFAMILY SSF52172 4 135 1.57E-26 T 12-10-2018 IPR011006 CheY-like superfamily VAPA_1c27470 01f3b507112cbc21d092e2ca0dba1d97 786 SUPERFAMILY SSF52540 172 407 5.13E-16 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c27470 01f3b507112cbc21d092e2ca0dba1d97 786 SMART SM00491 620 755 1.5E-7 T 12-10-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 VAPA_1c27470 01f3b507112cbc21d092e2ca0dba1d97 786 Pfam PF13307 Helicase C-terminal domain 607 767 5.4E-31 T 12-10-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 VAPA_1c27470 01f3b507112cbc21d092e2ca0dba1d97 786 Gene3D G3DSA:3.40.50.300 574 771 4.8E-46 T 12-10-2018 VAPA_1c27470 01f3b507112cbc21d092e2ca0dba1d97 786 SMART SM00488 195 437 4.4E-4 T 12-10-2018 IPR006554 Helicase-like, DEXD box c2 type GO:0004003|GO:0016818 VAPA_1c27470 01f3b507112cbc21d092e2ca0dba1d97 786 Pfam PF06733 DEAD_2 284 406 2.4E-11 T 12-10-2018 IPR010614 DEAD2 GO:0003677|GO:0004003|GO:0005524 VAPA_1c27470 01f3b507112cbc21d092e2ca0dba1d97 786 SUPERFAMILY SSF52540 215 749 2.93E-12 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c27470 01f3b507112cbc21d092e2ca0dba1d97 786 Gene3D G3DSA:3.40.50.300 205 558 6.3E-41 T 12-10-2018 VAPA_1c27470 01f3b507112cbc21d092e2ca0dba1d97 786 Gene3D G3DSA:1.10.275.30 403 521 6.3E-41 T 12-10-2018 VAPA_2c01750 5f89c92cbc962b496dd839a8c2d50559 342 TIGRFAM TIGR00787 dctP: TRAP transporter solute receptor, DctP family 61 296 9.4E-55 T 12-10-2018 IPR004682 TRAP transporter solute receptor, DctP family GO:0030288|GO:0055085 VAPA_2c01750 5f89c92cbc962b496dd839a8c2d50559 342 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 55 324 3.3E-62 T 12-10-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0030288|GO:0055085 VAPA_2c01750 5f89c92cbc962b496dd839a8c2d50559 342 Gene3D G3DSA:3.40.190.170 37 341 2.4E-76 T 12-10-2018 IPR038404 TRAP transporter solute receptor DctP superfamily VAPA_2c01750 5f89c92cbc962b496dd839a8c2d50559 342 PIRSF PIRSF006470 7 339 2.1E-68 T 12-10-2018 IPR004682 TRAP transporter solute receptor, DctP family GO:0030288|GO:0055085 VAPA_1c29690 6c29d7365ddab0d117f28acdc85b33cc 256 Gene3D G3DSA:3.40.50.720 1 256 9.2E-79 T 12-10-2018 VAPA_1c29690 6c29d7365ddab0d117f28acdc85b33cc 256 TIGRFAM TIGR01963 PHB_DH: 3-hydroxybutyrate dehydrogenase 5 256 1.7E-109 T 12-10-2018 IPR011294 3-hydroxybutyrate dehydrogenase GO:0003858|GO:0055114 VAPA_1c29690 6c29d7365ddab0d117f28acdc85b33cc 256 Pfam PF00106 short chain dehydrogenase 5 195 6.6E-58 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c29690 6c29d7365ddab0d117f28acdc85b33cc 256 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 5 177 0.0031 T 12-10-2018 VAPA_1c29690 6c29d7365ddab0d117f28acdc85b33cc 256 SUPERFAMILY SSF51735 3 255 3.88E-74 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c29690 6c29d7365ddab0d117f28acdc85b33cc 256 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 138 166 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 VAPA_1c29690 6c29d7365ddab0d117f28acdc85b33cc 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 78 89 2.4E-37 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c29690 6c29d7365ddab0d117f28acdc85b33cc 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 2.4E-37 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c29690 6c29d7365ddab0d117f28acdc85b33cc 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 172 189 2.4E-37 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c29690 6c29d7365ddab0d117f28acdc85b33cc 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 151 170 2.4E-37 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c29690 6c29d7365ddab0d117f28acdc85b33cc 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 217 237 2.4E-37 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c29690 6c29d7365ddab0d117f28acdc85b33cc 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 125 141 2.4E-37 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c29690 6c29d7365ddab0d117f28acdc85b33cc 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 131 139 2.8E-14 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c29690 6c29d7365ddab0d117f28acdc85b33cc 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 151 170 2.8E-14 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c29690 6c29d7365ddab0d117f28acdc85b33cc 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 78 89 2.8E-14 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c37490 553e42571bcfbd69fc7e467c5afead8f 142 Pfam PF00571 CBS domain 19 59 1.1E-5 T 12-10-2018 IPR000644 CBS domain VAPA_1c37490 553e42571bcfbd69fc7e467c5afead8f 142 Pfam PF00571 CBS domain 72 123 2.0E-11 T 12-10-2018 IPR000644 CBS domain VAPA_1c37490 553e42571bcfbd69fc7e467c5afead8f 142 SUPERFAMILY SSF54631 10 139 2.53E-30 T 12-10-2018 VAPA_1c37490 553e42571bcfbd69fc7e467c5afead8f 142 SMART SM00116 14 61 1.4 T 12-10-2018 IPR000644 CBS domain VAPA_1c37490 553e42571bcfbd69fc7e467c5afead8f 142 SMART SM00116 79 126 1.2E-6 T 12-10-2018 IPR000644 CBS domain VAPA_1c37490 553e42571bcfbd69fc7e467c5afead8f 142 Gene3D G3DSA:3.10.580.10 1 131 4.9E-41 T 12-10-2018 VAPA_2c10160 f2a23923754c748972a6fa8fc74bdf50 431 Pfam PF04773 FecR protein 110 210 3.8E-16 T 12-10-2018 IPR006860 FecR protein VAPA_2c10160 f2a23923754c748972a6fa8fc74bdf50 431 Gene3D G3DSA:3.10.350.10 24 69 2.5E-8 T 12-10-2018 IPR036779 LysM domain superfamily VAPA_2c10160 f2a23923754c748972a6fa8fc74bdf50 431 Gene3D G3DSA:2.60.40.10 348 422 1.3E-7 T 12-10-2018 IPR013783 Immunoglobulin-like fold VAPA_2c10160 f2a23923754c748972a6fa8fc74bdf50 431 Gene3D G3DSA:2.60.120.1440 110 241 6.1E-9 T 12-10-2018 VAPA_2c10160 f2a23923754c748972a6fa8fc74bdf50 431 SUPERFAMILY SSF54106 24 69 6.8E-5 T 12-10-2018 VAPA_2c10160 f2a23923754c748972a6fa8fc74bdf50 431 Pfam PF01476 LysM domain 25 69 1.4E-7 T 12-10-2018 IPR018392 LysM domain VAPA_1c49950 0905ff9ab6ddbf88a1967d572f50987f 389 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 90 99 - T 12-10-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 VAPA_1c49950 0905ff9ab6ddbf88a1967d572f50987f 389 SUPERFAMILY SSF55031 195 296 6.43E-21 T 12-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain VAPA_1c49950 0905ff9ab6ddbf88a1967d572f50987f 389 Gene3D G3DSA:3.30.70.360 195 304 8.1E-111 T 12-10-2018 VAPA_1c49950 0905ff9ab6ddbf88a1967d572f50987f 389 Gene3D G3DSA:3.40.630.10 30 377 8.1E-111 T 12-10-2018 VAPA_1c49950 0905ff9ab6ddbf88a1967d572f50987f 389 SUPERFAMILY SSF53187 15 386 1.89E-49 T 12-10-2018 VAPA_1c49950 0905ff9ab6ddbf88a1967d572f50987f 389 Pfam PF01546 Peptidase family M20/M25/M40 91 386 3.4E-24 T 12-10-2018 IPR002933 Peptidase M20 GO:0016787 VAPA_1c49950 0905ff9ab6ddbf88a1967d572f50987f 389 PIRSF PIRSF037238 14 388 4.8E-109 T 12-10-2018 IPR017150 Peptidase M20, glutamate carboxypeptidase VAPA_1c49950 0905ff9ab6ddbf88a1967d572f50987f 389 Pfam PF07687 Peptidase dimerisation domain 192 292 1.4E-21 T 12-10-2018 IPR011650 Peptidase M20, dimerisation domain VAPA_1c03810 a24c055b972f1737f292f5b5847413b9 448 PIRSF PIRSF004810 2 447 4.5E-131 T 12-10-2018 IPR014047 Chromate transporter, long chain VAPA_1c03810 a24c055b972f1737f292f5b5847413b9 448 TIGRFAM TIGR00937 2A51: chromate efflux transporter 23 440 3.9E-70 T 12-10-2018 IPR014047 Chromate transporter, long chain VAPA_1c03810 a24c055b972f1737f292f5b5847413b9 448 Pfam PF02417 Chromate transporter 16 180 1.1E-35 T 12-10-2018 IPR003370 Chromate transporter GO:0015109|GO:0015703 VAPA_1c03810 a24c055b972f1737f292f5b5847413b9 448 Pfam PF02417 Chromate transporter 256 440 3.2E-32 T 12-10-2018 IPR003370 Chromate transporter GO:0015109|GO:0015703 VAPA_1c29190 756ddf09712aec536f0a9837f0a22a8f 385 Gene3D G3DSA:1.20.1250.20 3 382 4.9E-44 T 12-10-2018 VAPA_1c29190 756ddf09712aec536f0a9837f0a22a8f 385 SUPERFAMILY SSF103473 5 383 5.75E-54 T 12-10-2018 IPR036259 MFS transporter superfamily VAPA_1c29190 756ddf09712aec536f0a9837f0a22a8f 385 Pfam PF07690 Major Facilitator Superfamily 14 322 1.7E-30 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 VAPA_1c36720 eb3e4ba5cb16a5c50179794f7a44eb14 455 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 139 370 1.4E-43 T 12-10-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain VAPA_1c36720 eb3e4ba5cb16a5c50179794f7a44eb14 455 Gene3D G3DSA:2.40.50.100 156 297 1.6E-80 T 12-10-2018 VAPA_1c36720 eb3e4ba5cb16a5c50179794f7a44eb14 455 SUPERFAMILY SSF111369 154 375 3.79E-26 T 12-10-2018 VAPA_1c36720 eb3e4ba5cb16a5c50179794f7a44eb14 455 Gene3D G3DSA:2.40.30.170 142 376 1.6E-80 T 12-10-2018 VAPA_1c36720 eb3e4ba5cb16a5c50179794f7a44eb14 455 Gene3D G3DSA:1.10.287.470 190 262 1.6E-80 T 12-10-2018 VAPA_1c36720 eb3e4ba5cb16a5c50179794f7a44eb14 455 Pfam PF00529 HlyD membrane-fusion protein of T1SS 371 434 2.7E-7 T 12-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 VAPA_1c36720 eb3e4ba5cb16a5c50179794f7a44eb14 455 Gene3D G3DSA:2.40.420.20 131 431 1.6E-80 T 12-10-2018 VAPA_1c36720 eb3e4ba5cb16a5c50179794f7a44eb14 455 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 130 432 6.7E-50 T 12-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 VAPA_1c00100 04ba0bd38d495b4dd07741bfa130040d 191 Pfam PF09411 Lipid A 3-O-deacylase (PagL) 55 187 1.1E-34 T 12-10-2018 IPR018550 Lipid A 3-O-deacylase-related VAPA_1c00100 04ba0bd38d495b4dd07741bfa130040d 191 Gene3D G3DSA:2.40.160.20 28 190 1.2E-36 T 12-10-2018 VAPA_1c00100 04ba0bd38d495b4dd07741bfa130040d 191 SUPERFAMILY SSF56925 34 186 2.09E-5 T 12-10-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel VAPA_1c35440 554d2e6ef0311e5fa1428da2d21722b9 381 SUPERFAMILY SSF51197 6 300 4.12E-66 T 12-10-2018 VAPA_1c35440 554d2e6ef0311e5fa1428da2d21722b9 381 Gene3D G3DSA:2.60.120.650 1 212 1.2E-77 T 12-10-2018 VAPA_1c35440 554d2e6ef0311e5fa1428da2d21722b9 381 Gene3D G3DSA:1.10.10.2510 221 381 1.4E-10 T 12-10-2018 VAPA_1c35440 554d2e6ef0311e5fa1428da2d21722b9 381 Pfam PF08007 Cupin superfamily protein 16 296 2.0E-81 T 12-10-2018 IPR003347 JmjC domain VAPA_1c38330 f991576036c1bc40a46bdeb74b9f7201 608 TIGRFAM TIGR01196 edd: phosphogluconate dehydratase 4 606 9.7E-273 T 12-10-2018 IPR004786 6-phosphogluconate dehydratase GO:0004456|GO:0009255 KEGG: 00030+4.2.1.12 VAPA_1c38330 f991576036c1bc40a46bdeb74b9f7201 608 SUPERFAMILY SSF143975 4 421 4.18E-136 T 12-10-2018 IPR037237 IlvD/EDD, N-terminal domain KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 VAPA_1c38330 f991576036c1bc40a46bdeb74b9f7201 608 ProSitePatterns PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2. 508 519 - T 12-10-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 VAPA_1c38330 f991576036c1bc40a46bdeb74b9f7201 608 Hamap MF_02094 Phosphogluconate dehydratase [edd]. 3 608 55.633 T 12-10-2018 VAPA_1c38330 f991576036c1bc40a46bdeb74b9f7201 608 Pfam PF00920 Dehydratase family 68 604 1.4E-158 T 12-10-2018 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 VAPA_1c38330 f991576036c1bc40a46bdeb74b9f7201 608 Gene3D G3DSA:3.50.30.80 422 572 2.0E-53 T 12-10-2018 VAPA_1c38330 f991576036c1bc40a46bdeb74b9f7201 608 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 156 166 - T 12-10-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 VAPA_1c38330 f991576036c1bc40a46bdeb74b9f7201 608 SUPERFAMILY SSF52016 422 606 9.42E-58 T 12-10-2018 VAPA_1c19980 745b2923a19764465a4a14d23a97a2b0 243 Gene3D G3DSA:1.10.10.10 129 237 1.2E-31 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c19980 745b2923a19764465a4a14d23a97a2b0 243 SMART SM00448 5 115 1.9E-43 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_1c19980 745b2923a19764465a4a14d23a97a2b0 243 Pfam PF00072 Response regulator receiver domain 7 116 3.1E-30 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_1c19980 745b2923a19764465a4a14d23a97a2b0 243 SUPERFAMILY SSF52172 4 128 5.12E-43 T 12-10-2018 IPR011006 CheY-like superfamily VAPA_1c19980 745b2923a19764465a4a14d23a97a2b0 243 Pfam PF00486 Transcriptional regulatory protein, C terminal 160 232 2.2E-22 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 VAPA_1c19980 745b2923a19764465a4a14d23a97a2b0 243 SUPERFAMILY SSF46894 137 233 3.97E-25 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 VAPA_1c19980 745b2923a19764465a4a14d23a97a2b0 243 Gene3D G3DSA:3.40.50.2300 1 128 1.3E-38 T 12-10-2018 VAPA_1c19980 745b2923a19764465a4a14d23a97a2b0 243 SMART SM00862 156 232 1.4E-21 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 VAPA_1c24110 46017b6b7185608b9982f453bd4596f1 129 Pfam PF04343 Protein of unknown function, DUF488 23 119 6.3E-14 T 12-10-2018 IPR007438 Protein of unknown function DUF488 VAPA_1c10830 8d7267f9de429de781ef05f59d68d6ff 109 Pfam PF03860 Domain of Unknown Function (DUF326) 87 106 4.6E-5 T 12-10-2018 IPR005560 Protein of unknown function DUF326 VAPA_1c10830 8d7267f9de429de781ef05f59d68d6ff 109 Gene3D G3DSA:1.20.1270.360 3 109 5.0E-32 T 12-10-2018 VAPA_1c09670 082f421c0ec0633e20a4d8939be47918 517 SUPERFAMILY SSF53623 99 352 6.87E-60 T 12-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 VAPA_1c09670 082f421c0ec0633e20a4d8939be47918 517 SUPERFAMILY SSF53244 355 513 4.32E-45 T 12-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 VAPA_1c09670 082f421c0ec0633e20a4d8939be47918 517 Gene3D G3DSA:3.40.1190.10 99 357 1.0E-67 T 12-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 VAPA_1c09670 082f421c0ec0633e20a4d8939be47918 517 Pfam PF02875 Mur ligase family, glutamate ligase domain 355 445 8.0E-21 T 12-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 VAPA_1c09670 082f421c0ec0633e20a4d8939be47918 517 Gene3D G3DSA:3.90.190.20 358 515 2.1E-52 T 12-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 VAPA_1c09670 082f421c0ec0633e20a4d8939be47918 517 Gene3D G3DSA:3.40.1390.10 5 98 1.2E-14 T 12-10-2018 VAPA_1c09670 082f421c0ec0633e20a4d8939be47918 517 Hamap MF_00208 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [murE]. 2 511 30.378 T 12-10-2018 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 VAPA_1c09670 082f421c0ec0633e20a4d8939be47918 517 TIGRFAM TIGR01085 murE: UDP-N-acetylmuramyl-tripeptide synthetase 151 509 3.4E-107 T 12-10-2018 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 VAPA_1c09670 082f421c0ec0633e20a4d8939be47918 517 SUPERFAMILY SSF63418 14 97 5.36E-16 T 12-10-2018 IPR035911 MurE/MurF, N-terminal VAPA_1c09670 082f421c0ec0633e20a4d8939be47918 517 Pfam PF08245 Mur ligase middle domain 108 333 2.0E-40 T 12-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 VAPA_1c09670 082f421c0ec0633e20a4d8939be47918 517 Pfam PF01225 Mur ligase family, catalytic domain 24 66 2.1E-5 T 12-10-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 VAPA_1c45050 0ca3cf91aa713db3d2c321cd8d0592be 303 Gene3D G3DSA:3.40.50.10330 31 298 1.5E-84 T 12-10-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, N-terminal GO:0003951 VAPA_1c45050 0ca3cf91aa713db3d2c321cd8d0592be 303 Pfam PF01513 ATP-NAD kinase 68 281 4.1E-52 T 12-10-2018 IPR002504 NAD kinase GO:0003951|GO:0006741 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 VAPA_1c45050 0ca3cf91aa713db3d2c321cd8d0592be 303 Gene3D G3DSA:2.60.200.30 140 275 1.5E-84 T 12-10-2018 IPR017437 ATP-NAD kinase, PpnK-type, C-terminal GO:0003951|GO:0019674 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 VAPA_1c45050 0ca3cf91aa713db3d2c321cd8d0592be 303 SUPERFAMILY SSF111331 31 300 2.09E-78 T 12-10-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain superfamily VAPA_1c45050 0ca3cf91aa713db3d2c321cd8d0592be 303 Hamap MF_00361 NAD kinase [nadK]. 6 298 30.363 T 12-10-2018 IPR002504 NAD kinase GO:0003951|GO:0006741 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 VAPA_1c25550 ed719e3b8ea79d84985c9c20199f42bc 517 SUPERFAMILY SSF53850 32 511 7.7E-136 T 12-10-2018 VAPA_1c25550 ed719e3b8ea79d84985c9c20199f42bc 517 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 72 433 9.4E-97 T 12-10-2018 IPR000914 Solute-binding protein family 5 domain VAPA_1c25550 ed719e3b8ea79d84985c9c20199f42bc 517 Gene3D G3DSA:3.40.190.10 189 500 3.7E-156 T 12-10-2018 VAPA_1c25550 ed719e3b8ea79d84985c9c20199f42bc 517 Gene3D G3DSA:3.90.76.10 39 188 3.7E-156 T 12-10-2018 VAPA_1c25550 ed719e3b8ea79d84985c9c20199f42bc 517 Gene3D G3DSA:3.10.105.10 264 490 3.7E-156 T 12-10-2018 VAPA_1c25550 ed719e3b8ea79d84985c9c20199f42bc 517 PIRSF PIRSF002741 7 516 2.4E-112 T 12-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 VAPA_1c42920 8a305d5495b90689afb7a506ac5b37dd 335 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_1c42920 8a305d5495b90689afb7a506ac5b37dd 335 SUPERFAMILY SSF50331 240 333 3.89E-21 T 12-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal VAPA_1c42920 8a305d5495b90689afb7a506ac5b37dd 335 Pfam PF08402 TOBE domain 258 326 2.4E-11 T 12-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 VAPA_1c42920 8a305d5495b90689afb7a506ac5b37dd 335 Gene3D G3DSA:2.40.50.140 265 318 1.9E-10 T 12-10-2018 VAPA_1c42920 8a305d5495b90689afb7a506ac5b37dd 335 Gene3D G3DSA:2.40.50.940 257 327 1.9E-10 T 12-10-2018 VAPA_1c42920 8a305d5495b90689afb7a506ac5b37dd 335 SUPERFAMILY SSF52540 4 247 6.36E-83 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c42920 8a305d5495b90689afb7a506ac5b37dd 335 Pfam PF00005 ABC transporter 24 165 6.3E-30 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c42920 8a305d5495b90689afb7a506ac5b37dd 335 Gene3D G3DSA:2.40.50.940 226 248 3.2E-10 T 12-10-2018 VAPA_1c42920 8a305d5495b90689afb7a506ac5b37dd 335 Gene3D G3DSA:3.40.50.300 3 225 2.5E-62 T 12-10-2018 VAPA_1c42920 8a305d5495b90689afb7a506ac5b37dd 335 SMART SM00382 32 215 1.6E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c29560 95038c270228130b69ea24d7c6080e58 486 Pfam PF01256 Carbohydrate kinase 245 471 5.2E-42 T 12-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 VAPA_1c29560 95038c270228130b69ea24d7c6080e58 486 Hamap MF_01965 ADP-dependent (S)-NAD(P)H-hydrate dehydratase [nnrD]. 222 485 16.348 T 12-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 VAPA_1c29560 95038c270228130b69ea24d7c6080e58 486 Pfam PF03853 YjeF-related protein N-terminus 32 193 8.0E-37 T 12-10-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 VAPA_1c29560 95038c270228130b69ea24d7c6080e58 486 Gene3D G3DSA:3.40.1190.20 228 486 2.0E-62 T 12-10-2018 IPR029056 Ribokinase-like VAPA_1c29560 95038c270228130b69ea24d7c6080e58 486 SUPERFAMILY SSF53613 232 484 3.9E-52 T 12-10-2018 IPR029056 Ribokinase-like VAPA_1c29560 95038c270228130b69ea24d7c6080e58 486 Hamap MF_01966 NAD(P)H-hydrate epimerase [nnrE]. 5 214 20.254 T 12-10-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 VAPA_1c29560 95038c270228130b69ea24d7c6080e58 486 TIGRFAM TIGR00196 yjeF_cterm: YjeF family C-terminal domain 232 468 1.1E-46 T 12-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 VAPA_1c29560 95038c270228130b69ea24d7c6080e58 486 Gene3D G3DSA:3.40.50.10260 13 219 7.8E-51 T 12-10-2018 IPR036652 YjeF N-terminal domain superfamily MetaCyc: PWY-6938 VAPA_1c29560 95038c270228130b69ea24d7c6080e58 486 TIGRFAM TIGR00197 yjeF_nterm: YjeF family N-terminal domain 24 212 8.4E-31 T 12-10-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 VAPA_1c29560 95038c270228130b69ea24d7c6080e58 486 ProSitePatterns PS01050 YjeF C-terminal domain signature 2. 430 440 - T 12-10-2018 IPR017953 Carbohydrate kinase, predicted, conserved site VAPA_1c29560 95038c270228130b69ea24d7c6080e58 486 PIRSF PIRSF017184 11 485 6.4E-89 T 12-10-2018 IPR030677 Bifunctional NAD(P)H-hydrate repair enzyme Nnr GO:0052855 MetaCyc: PWY-6938 VAPA_1c29560 95038c270228130b69ea24d7c6080e58 486 SUPERFAMILY SSF64153 12 243 5.62E-51 T 12-10-2018 IPR036652 YjeF N-terminal domain superfamily MetaCyc: PWY-6938 VAPA_1c47100 36af58653f80a9012236efb8a0060918 1869 SUPERFAMILY SSF49313 644 734 1.71E-12 T 12-10-2018 IPR015919 Cadherin-like superfamily GO:0005509|GO:0016020 VAPA_1c47100 36af58653f80a9012236efb8a0060918 1869 SUPERFAMILY SSF49313 1054 1145 4.14E-12 T 12-10-2018 IPR015919 Cadherin-like superfamily GO:0005509|GO:0016020 VAPA_1c47100 36af58653f80a9012236efb8a0060918 1869 SMART SM00112 175 249 0.055 T 12-10-2018 IPR002126 Cadherin-like GO:0005509|GO:0007156|GO:0016020 VAPA_1c47100 36af58653f80a9012236efb8a0060918 1869 SMART SM00112 267 341 0.75 T 12-10-2018 IPR002126 Cadherin-like GO:0005509|GO:0007156|GO:0016020 VAPA_1c47100 36af58653f80a9012236efb8a0060918 1869 SMART SM00112 669 751 0.0028 T 12-10-2018 IPR002126 Cadherin-like GO:0005509|GO:0007156|GO:0016020 VAPA_1c47100 36af58653f80a9012236efb8a0060918 1869 SMART SM00112 473 546 0.67 T 12-10-2018 IPR002126 Cadherin-like GO:0005509|GO:0007156|GO:0016020 VAPA_1c47100 36af58653f80a9012236efb8a0060918 1869 SMART SM00112 373 455 1.3E-4 T 12-10-2018 IPR002126 Cadherin-like GO:0005509|GO:0007156|GO:0016020 VAPA_1c47100 36af58653f80a9012236efb8a0060918 1869 SMART SM00112 1079 1161 0.0023 T 12-10-2018 IPR002126 Cadherin-like GO:0005509|GO:0007156|GO:0016020 VAPA_1c47100 36af58653f80a9012236efb8a0060918 1869 SMART SM00112 874 956 1.3E-4 T 12-10-2018 IPR002126 Cadherin-like GO:0005509|GO:0007156|GO:0016020 VAPA_1c47100 36af58653f80a9012236efb8a0060918 1869 Gene3D G3DSA:3.40.50.410 1422 1624 1.2E-23 T 12-10-2018 IPR036465 von Willebrand factor A-like domain superfamily VAPA_1c47100 36af58653f80a9012236efb8a0060918 1869 SUPERFAMILY SSF49313 348 439 1.71E-12 T 12-10-2018 IPR015919 Cadherin-like superfamily GO:0005509|GO:0016020 VAPA_1c47100 36af58653f80a9012236efb8a0060918 1869 SUPERFAMILY SSF53300 1420 1619 4.15E-21 T 12-10-2018 IPR036465 von Willebrand factor A-like domain superfamily VAPA_1c47100 36af58653f80a9012236efb8a0060918 1869 Pfam PF13519 von Willebrand factor type A domain 1423 1530 3.7E-14 T 12-10-2018 IPR002035 von Willebrand factor, type A VAPA_1c47100 36af58653f80a9012236efb8a0060918 1869 SUPERFAMILY SSF49313 966 1044 3.14E-5 T 12-10-2018 IPR015919 Cadherin-like superfamily GO:0005509|GO:0016020 VAPA_1c47100 36af58653f80a9012236efb8a0060918 1869 Gene3D G3DSA:2.60.40.10 246 334 9.0E-6 T 12-10-2018 IPR013783 Immunoglobulin-like fold VAPA_1c47100 36af58653f80a9012236efb8a0060918 1869 Gene3D G3DSA:2.60.40.10 158 242 4.7E-9 T 12-10-2018 IPR013783 Immunoglobulin-like fold VAPA_1c47100 36af58653f80a9012236efb8a0060918 1869 Gene3D G3DSA:2.60.40.10 545 630 3.7E-6 T 12-10-2018 IPR013783 Immunoglobulin-like fold VAPA_1c47100 36af58653f80a9012236efb8a0060918 1869 Gene3D G3DSA:2.60.40.10 952 1040 2.8E-5 T 12-10-2018 IPR013783 Immunoglobulin-like fold VAPA_1c47100 36af58653f80a9012236efb8a0060918 1869 Gene3D G3DSA:2.60.40.10 1158 1245 1.2E-5 T 12-10-2018 IPR013783 Immunoglobulin-like fold VAPA_1c47100 36af58653f80a9012236efb8a0060918 1869 Gene3D G3DSA:2.60.40.10 451 539 2.5E-8 T 12-10-2018 IPR013783 Immunoglobulin-like fold VAPA_1c47100 36af58653f80a9012236efb8a0060918 1869 Gene3D G3DSA:2.60.40.10 749 835 6.1E-7 T 12-10-2018 IPR013783 Immunoglobulin-like fold VAPA_1c47100 36af58653f80a9012236efb8a0060918 1869 SUPERFAMILY SSF49313 849 940 1.71E-12 T 12-10-2018 IPR015919 Cadherin-like superfamily GO:0005509|GO:0016020 VAPA_1c47100 36af58653f80a9012236efb8a0060918 1869 Pfam PF00028 Cadherin domain 858 909 1.5E-7 T 12-10-2018 IPR002126 Cadherin-like GO:0005509|GO:0007156|GO:0016020 VAPA_1c47100 36af58653f80a9012236efb8a0060918 1869 Pfam PF00028 Cadherin domain 653 704 6.1E-8 T 12-10-2018 IPR002126 Cadherin-like GO:0005509|GO:0007156|GO:0016020 VAPA_1c47100 36af58653f80a9012236efb8a0060918 1869 Pfam PF00028 Cadherin domain 357 408 1.5E-7 T 12-10-2018 IPR002126 Cadherin-like GO:0005509|GO:0007156|GO:0016020 VAPA_1c47100 36af58653f80a9012236efb8a0060918 1869 Pfam PF00028 Cadherin domain 1063 1115 2.9E-7 T 12-10-2018 IPR002126 Cadherin-like GO:0005509|GO:0007156|GO:0016020 VAPA_1c47100 36af58653f80a9012236efb8a0060918 1869 SUPERFAMILY SSF49313 164 246 4.71E-9 T 12-10-2018 IPR015919 Cadherin-like superfamily GO:0005509|GO:0016020 VAPA_1c47100 36af58653f80a9012236efb8a0060918 1869 SUPERFAMILY SSF49313 465 543 2.75E-6 T 12-10-2018 IPR015919 Cadherin-like superfamily GO:0005509|GO:0016020 VAPA_1c47100 36af58653f80a9012236efb8a0060918 1869 SMART SM00327 1420 1613 6.3E-14 T 12-10-2018 IPR002035 von Willebrand factor, type A VAPA_1c47100 36af58653f80a9012236efb8a0060918 1869 TIGRFAM TIGR01965 VCBS_repeat: VCBS repeat 971 1048 1.4E-4 T 12-10-2018 IPR010221 VCBS repeat VAPA_1c47100 36af58653f80a9012236efb8a0060918 1869 TIGRFAM TIGR01965 VCBS_repeat: VCBS repeat 172 260 4.0E-4 T 12-10-2018 IPR010221 VCBS repeat VAPA_1c47100 36af58653f80a9012236efb8a0060918 1869 TIGRFAM TIGR01965 VCBS_repeat: VCBS repeat 1176 1263 1.1E-4 T 12-10-2018 IPR010221 VCBS repeat VAPA_1c47100 36af58653f80a9012236efb8a0060918 1869 TIGRFAM TIGR01965 VCBS_repeat: VCBS repeat 264 342 2.2E-6 T 12-10-2018 IPR010221 VCBS repeat VAPA_1c47100 36af58653f80a9012236efb8a0060918 1869 TIGRFAM TIGR01965 VCBS_repeat: VCBS repeat 561 638 5.7E-5 T 12-10-2018 IPR010221 VCBS repeat VAPA_1c47100 36af58653f80a9012236efb8a0060918 1869 TIGRFAM TIGR01965 VCBS_repeat: VCBS repeat 766 843 2.4E-5 T 12-10-2018 IPR010221 VCBS repeat VAPA_1c47100 36af58653f80a9012236efb8a0060918 1869 TIGRFAM TIGR01965 VCBS_repeat: VCBS repeat 470 549 8.4E-5 T 12-10-2018 IPR010221 VCBS repeat VAPA_1c47100 36af58653f80a9012236efb8a0060918 1869 SUPERFAMILY SSF49313 1171 1249 4.58E-5 T 12-10-2018 IPR015919 Cadherin-like superfamily GO:0005509|GO:0016020 VAPA_1c47100 36af58653f80a9012236efb8a0060918 1869 SUPERFAMILY SSF49313 260 338 1.16E-5 T 12-10-2018 IPR015919 Cadherin-like superfamily GO:0005509|GO:0016020 VAPA_1c47100 36af58653f80a9012236efb8a0060918 1869 SUPERFAMILY SSF49313 556 634 6.81E-6 T 12-10-2018 IPR015919 Cadherin-like superfamily GO:0005509|GO:0016020 VAPA_1c47100 36af58653f80a9012236efb8a0060918 1869 SUPERFAMILY SSF49313 759 839 6.44E-6 T 12-10-2018 IPR015919 Cadherin-like superfamily GO:0005509|GO:0016020 VAPA_1c47100 36af58653f80a9012236efb8a0060918 1869 Gene3D G3DSA:2.60.40.60 347 447 9.2E-15 T 12-10-2018 VAPA_1c47100 36af58653f80a9012236efb8a0060918 1869 Gene3D G3DSA:2.60.40.60 1053 1153 2.3E-14 T 12-10-2018 VAPA_1c47100 36af58653f80a9012236efb8a0060918 1869 Gene3D G3DSA:2.60.40.60 643 743 6.5E-15 T 12-10-2018 VAPA_1c47100 36af58653f80a9012236efb8a0060918 1869 Gene3D G3DSA:2.60.40.60 848 948 9.2E-15 T 12-10-2018 VAPA_2c03320 bbbde8f88aab548f76d871513f4a353b 217 Pfam PF04972 BON domain 151 216 3.5E-10 T 12-10-2018 IPR007055 BON domain VAPA_2c03320 bbbde8f88aab548f76d871513f4a353b 217 Pfam PF04972 BON domain 78 145 9.2E-16 T 12-10-2018 IPR007055 BON domain VAPA_2c03320 bbbde8f88aab548f76d871513f4a353b 217 Pfam PF04972 BON domain 3 67 2.8E-14 T 12-10-2018 IPR007055 BON domain VAPA_2c03320 bbbde8f88aab548f76d871513f4a353b 217 SMART SM00749 8 71 0.015 T 12-10-2018 IPR014004 Transport-associated and nodulation domain, bacteria VAPA_2c03320 bbbde8f88aab548f76d871513f4a353b 217 SMART SM00749 83 146 0.037 T 12-10-2018 IPR014004 Transport-associated and nodulation domain, bacteria VAPA_2c03320 bbbde8f88aab548f76d871513f4a353b 217 SMART SM00749 154 217 0.003 T 12-10-2018 IPR014004 Transport-associated and nodulation domain, bacteria VAPA_1c48600 e001d260be7d9fa11fa003b86f38b452 564 SUPERFAMILY SSF103473 18 558 3.84E-59 T 12-10-2018 IPR036259 MFS transporter superfamily VAPA_1c48600 e001d260be7d9fa11fa003b86f38b452 564 Gene3D G3DSA:1.20.1250.20 22 360 5.5E-54 T 12-10-2018 VAPA_1c48600 e001d260be7d9fa11fa003b86f38b452 564 Pfam PF00083 Sugar (and other) transporter 455 560 1.9E-5 T 12-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 VAPA_1c48600 e001d260be7d9fa11fa003b86f38b452 564 Pfam PF00083 Sugar (and other) transporter 27 242 1.7E-26 T 12-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 VAPA_1c48600 e001d260be7d9fa11fa003b86f38b452 564 Gene3D G3DSA:1.20.1250.20 438 563 4.6E-10 T 12-10-2018 VAPA_1c48600 e001d260be7d9fa11fa003b86f38b452 564 ProSitePatterns PS00217 Sugar transport proteins signature 2. 135 160 - T 12-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 VAPA_1c17150 4eae0625b249aa76002ddf025dd0fc26 881 Gene3D G3DSA:3.90.199.10 33 525 1.3E-222 T 12-10-2018 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 VAPA_1c17150 4eae0625b249aa76002ddf025dd0fc26 881 Gene3D G3DSA:2.120.10.90 543 857 4.2E-118 T 12-10-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal VAPA_1c17150 4eae0625b249aa76002ddf025dd0fc26 881 Gene3D G3DSA:3.30.1360.40 236 333 1.3E-222 T 12-10-2018 VAPA_1c17150 4eae0625b249aa76002ddf025dd0fc26 881 SUPERFAMILY SSF56719 30 524 4.45E-178 T 12-10-2018 IPR013760 DNA topoisomerase, type IIA-like domain superfamily GO:0003918|GO:0005524 Reactome: R-HSA-4615885 VAPA_1c17150 4eae0625b249aa76002ddf025dd0fc26 881 TIGRFAM TIGR01063 gyrA: DNA gyrase, A subunit 10 856 0.0 T 12-10-2018 VAPA_1c17150 4eae0625b249aa76002ddf025dd0fc26 881 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 32 505 3.0E-157 T 12-10-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 VAPA_1c17150 4eae0625b249aa76002ddf025dd0fc26 881 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 810 854 5.2E-12 T 12-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 VAPA_1c17150 4eae0625b249aa76002ddf025dd0fc26 881 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 660 704 3.3E-8 T 12-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 VAPA_1c17150 4eae0625b249aa76002ddf025dd0fc26 881 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 550 595 1.1E-8 T 12-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 VAPA_1c17150 4eae0625b249aa76002ddf025dd0fc26 881 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 760 806 9.5E-12 T 12-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 VAPA_1c17150 4eae0625b249aa76002ddf025dd0fc26 881 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 600 643 7.8E-9 T 12-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 VAPA_1c17150 4eae0625b249aa76002ddf025dd0fc26 881 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 709 754 7.3E-13 T 12-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 VAPA_1c17150 4eae0625b249aa76002ddf025dd0fc26 881 SUPERFAMILY SSF101904 545 865 7.72E-107 T 12-10-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal VAPA_1c17150 4eae0625b249aa76002ddf025dd0fc26 881 Hamap MF_01897 DNA gyrase subunit A [gyrA]. 7 858 23.764 T 12-10-2018 IPR005743 DNA gyrase, subunit A GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 VAPA_1c17150 4eae0625b249aa76002ddf025dd0fc26 881 SMART SM00434 11 507 4.4E-289 T 12-10-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 VAPA_1c17150 4eae0625b249aa76002ddf025dd0fc26 881 Gene3D G3DSA:1.10.268.10 370 501 1.3E-222 T 12-10-2018 IPR013757 Type IIA DNA topoisomerase subunit A, alpha-helical domain superfamily GO:0003677|GO:0003918|GO:0005524 Reactome: R-HSA-4615885 VAPA_1c21290 63f6d9d0830cea85d70fed5e7e53a75b 204 SUPERFAMILY SSF52499 17 185 1.11E-37 T 12-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 VAPA_1c21290 63f6d9d0830cea85d70fed5e7e53a75b 204 Gene3D G3DSA:3.40.50.850 6 193 1.7E-36 T 12-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 VAPA_1c21290 63f6d9d0830cea85d70fed5e7e53a75b 204 Pfam PF00857 Isochorismatase family 24 187 2.9E-25 T 12-10-2018 IPR000868 Isochorismatase-like GO:0003824 VAPA_1c21290 63f6d9d0830cea85d70fed5e7e53a75b 204 PRINTS PR01398 Isochorismatase signature 103 125 4.3E-5 T 12-10-2018 IPR016291 Isochorismatase GO:0008908 VAPA_1c21290 63f6d9d0830cea85d70fed5e7e53a75b 204 PRINTS PR01398 Isochorismatase signature 159 177 4.3E-5 T 12-10-2018 IPR016291 Isochorismatase GO:0008908 VAPA_1c21290 63f6d9d0830cea85d70fed5e7e53a75b 204 PRINTS PR01398 Isochorismatase signature 57 74 4.3E-5 T 12-10-2018 IPR016291 Isochorismatase GO:0008908 VAPA_1c04940 04c5eab98edaa5845de53146176de13c 693 Gene3D G3DSA:2.60.40.10 1 136 7.3E-41 T 12-10-2018 IPR013783 Immunoglobulin-like fold VAPA_1c04940 04c5eab98edaa5845de53146176de13c 693 SMART SM00642 155 578 2.1E-7 T 12-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 VAPA_1c04940 04c5eab98edaa5845de53146176de13c 693 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 11 97 3.4E-15 T 12-10-2018 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 VAPA_1c04940 04c5eab98edaa5845de53146176de13c 693 Gene3D G3DSA:2.60.40.1180 598 692 3.7E-8 T 12-10-2018 IPR013780 Glycosyl hydrolase, all-beta VAPA_1c04940 04c5eab98edaa5845de53146176de13c 693 SUPERFAMILY SSF51011 597 689 2.66E-13 T 12-10-2018 VAPA_1c04940 04c5eab98edaa5845de53146176de13c 693 SUPERFAMILY SSF51445 148 586 7.31E-116 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily VAPA_1c04940 04c5eab98edaa5845de53146176de13c 693 Gene3D G3DSA:3.20.20.80 143 592 2.7E-155 T 12-10-2018 VAPA_1c04940 04c5eab98edaa5845de53146176de13c 693 SUPERFAMILY SSF81296 4 128 2.0E-38 T 12-10-2018 IPR014756 Immunoglobulin E-set VAPA_1c04940 04c5eab98edaa5845de53146176de13c 693 Pfam PF00128 Alpha amylase, catalytic domain 189 307 5.7E-7 T 12-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 VAPA_1c04940 04c5eab98edaa5845de53146176de13c 693 TIGRFAM TIGR02100 glgX_debranch: glycogen debranching enzyme GlgX 5 688 8.3E-259 T 12-10-2018 IPR011837 Glycogen debranching enzyme, GlgX type GO:0004133|GO:0004553|GO:0005980 VAPA_1c36000 a725cdfafd100a5fe423fe539b0f220f 178 SUPERFAMILY SSF46785 26 169 1.29E-32 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c36000 a725cdfafd100a5fe423fe539b0f220f 178 SMART SM00347 53 153 5.2E-24 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 VAPA_1c36000 a725cdfafd100a5fe423fe539b0f220f 178 Pfam PF01047 MarR family 63 118 8.8E-14 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 VAPA_1c36000 a725cdfafd100a5fe423fe539b0f220f 178 Gene3D G3DSA:1.10.10.10 25 176 3.7E-33 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c36000 a725cdfafd100a5fe423fe539b0f220f 178 ProSitePatterns PS01117 MarR-type HTH domain signature. 92 126 - T 12-10-2018 IPR023187 Transcriptional regulator MarR-type, conserved site VAPA_1c36000 a725cdfafd100a5fe423fe539b0f220f 178 PRINTS PR00598 Bacterial regulatory protein MarR family signature 77 93 1.2E-15 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 VAPA_1c36000 a725cdfafd100a5fe423fe539b0f220f 178 PRINTS PR00598 Bacterial regulatory protein MarR family signature 94 109 1.2E-15 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 VAPA_1c36000 a725cdfafd100a5fe423fe539b0f220f 178 PRINTS PR00598 Bacterial regulatory protein MarR family signature 113 129 1.2E-15 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 VAPA_1c36000 a725cdfafd100a5fe423fe539b0f220f 178 PRINTS PR00598 Bacterial regulatory protein MarR family signature 143 163 1.2E-15 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 VAPA_1c32190 5c625a08ed713fc9ecaaaa12d0976374 311 Gene3D G3DSA:3.40.190.10 48 259 2.2E-49 T 12-10-2018 VAPA_1c32190 5c625a08ed713fc9ecaaaa12d0976374 311 Pfam PF12974 ABC transporter, phosphonate, periplasmic substrate-binding protein 51 260 1.0E-52 T 12-10-2018 VAPA_1c32190 5c625a08ed713fc9ecaaaa12d0976374 311 Gene3D G3DSA:3.40.190.10 122 230 2.2E-49 T 12-10-2018 VAPA_1c32190 5c625a08ed713fc9ecaaaa12d0976374 311 SUPERFAMILY SSF53850 52 288 6.22E-36 T 12-10-2018 VAPA_1c32190 5c625a08ed713fc9ecaaaa12d0976374 311 TIGRFAM TIGR01098 3A0109s03R: phosphate/phosphite/phosphonate ABC transporter, periplasmic binding protein 1 254 1.2E-47 T 12-10-2018 IPR005770 Phosphate/phosphite/phosphonate ABC transporter, periplasmic binding protein GO:0043190|GO:0055085 VAPA_1c00120 4784987c299953300b57d0a16265008c 422 SUPERFAMILY SSF56024 180 351 2.09E-40 T 12-10-2018 VAPA_1c00120 4784987c299953300b57d0a16265008c 422 SUPERFAMILY SSF56024 3 173 6.95E-39 T 12-10-2018 VAPA_1c00120 4784987c299953300b57d0a16265008c 422 Gene3D G3DSA:3.30.870.10 3 178 5.6E-36 T 12-10-2018 VAPA_1c00120 4784987c299953300b57d0a16265008c 422 SMART SM00155 110 137 3.4E-7 T 12-10-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 VAPA_1c00120 4784987c299953300b57d0a16265008c 422 SMART SM00155 290 317 14.0 T 12-10-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 VAPA_1c00120 4784987c299953300b57d0a16265008c 422 Gene3D G3DSA:3.30.870.10 196 371 2.0E-26 T 12-10-2018 VAPA_1c00120 4784987c299953300b57d0a16265008c 422 Pfam PF13091 PLD-like domain 219 343 5.0E-27 T 12-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 VAPA_1c00120 4784987c299953300b57d0a16265008c 422 Pfam PF13091 PLD-like domain 28 156 1.9E-14 T 12-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 VAPA_1c00120 4784987c299953300b57d0a16265008c 422 Hamap MF_01917 Cardiolipin synthase B [clsB]. 4 389 50.186 T 12-10-2018 IPR030872 Cardiolipin synthase B GO:0008808|GO:0032049 VAPA_1c14280 3bbe8b2763325990d68676b9e53bb197 229 SMART SM00345 14 73 7.9E-19 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_1c14280 3bbe8b2763325990d68676b9e53bb197 229 Pfam PF00392 Bacterial regulatory proteins, gntR family 11 73 4.9E-19 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_1c14280 3bbe8b2763325990d68676b9e53bb197 229 SUPERFAMILY SSF46785 5 107 2.7E-21 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c14280 3bbe8b2763325990d68676b9e53bb197 229 Gene3D G3DSA:1.20.120.530 87 224 4.5E-25 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal VAPA_1c14280 3bbe8b2763325990d68676b9e53bb197 229 Pfam PF07729 FCD domain 95 213 5.1E-23 T 12-10-2018 IPR011711 GntR, C-terminal VAPA_1c14280 3bbe8b2763325990d68676b9e53bb197 229 SUPERFAMILY SSF48008 90 220 2.43E-25 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal VAPA_1c14280 3bbe8b2763325990d68676b9e53bb197 229 Gene3D G3DSA:1.10.10.10 5 76 9.7E-23 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c14280 3bbe8b2763325990d68676b9e53bb197 229 SMART SM00895 93 216 1.9E-21 T 12-10-2018 IPR011711 GntR, C-terminal VAPA_1c14280 3bbe8b2763325990d68676b9e53bb197 229 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 47 63 3.2E-8 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_1c14280 3bbe8b2763325990d68676b9e53bb197 229 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 33 47 3.2E-8 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_2c04360 14ddfdf702c65dd2addfe6998c9bb849 158 Gene3D G3DSA:3.90.79.10 2 131 7.3E-18 T 12-10-2018 VAPA_2c04360 14ddfdf702c65dd2addfe6998c9bb849 158 ProSitePatterns PS00893 Nudix box signature. 33 54 - T 12-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 VAPA_2c04360 14ddfdf702c65dd2addfe6998c9bb849 158 SUPERFAMILY SSF55811 7 126 6.91E-18 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 VAPA_2c04360 14ddfdf702c65dd2addfe6998c9bb849 158 Pfam PF00293 NUDIX domain 5 119 2.5E-11 T 12-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 VAPA_1c35210 f6d44271d4d54f4176480fd5fab6efbe 317 Pfam PF00294 pfkB family carbohydrate kinase 8 308 2.6E-56 T 12-10-2018 IPR011611 Carbohydrate kinase PfkB VAPA_1c35210 f6d44271d4d54f4176480fd5fab6efbe 317 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 260 273 - T 12-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 VAPA_1c35210 f6d44271d4d54f4176480fd5fab6efbe 317 SUPERFAMILY SSF53613 7 314 2.49E-83 T 12-10-2018 IPR029056 Ribokinase-like VAPA_1c35210 f6d44271d4d54f4176480fd5fab6efbe 317 Gene3D G3DSA:3.40.1190.20 6 316 2.0E-92 T 12-10-2018 IPR029056 Ribokinase-like VAPA_1c42070 0100462f13aa0ef3084354320533a390 493 Gene3D G3DSA:3.40.50.300 1 55 6.2E-8 T 12-10-2018 VAPA_1c42070 0100462f13aa0ef3084354320533a390 493 Pfam PF13304 AAA domain, putative AbiEii toxin, Type IV TA system 315 417 2.6E-10 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 VAPA_1c42070 0100462f13aa0ef3084354320533a390 493 Gene3D G3DSA:3.40.50.300 243 425 9.7E-7 T 12-10-2018 VAPA_1c42070 0100462f13aa0ef3084354320533a390 493 Pfam PF13175 AAA ATPase domain 1 46 8.4E-8 T 12-10-2018 VAPA_1c42070 0100462f13aa0ef3084354320533a390 493 SUPERFAMILY SSF52540 1 418 1.59E-18 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c13720 1102570d106d16008fc67b9c51cbb879 296 Gene3D G3DSA:3.90.550.10 3 295 3.3E-87 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases VAPA_1c13720 1102570d106d16008fc67b9c51cbb879 296 TIGRFAM TIGR01099 galU: UTP--glucose-1-phosphate uridylyltransferase 8 272 4.6E-111 T 12-10-2018 IPR005771 UTP--glucose-1-phosphate uridylyltransferase, bacterial/archaeal-type GO:0003983|GO:0006011 KEGG: 00040+2.7.7.9|KEGG: 00052+2.7.7.9|KEGG: 00500+2.7.7.9|KEGG: 00520+2.7.7.9|MetaCyc: PWY-3801|MetaCyc: PWY-6527|MetaCyc: PWY-7238|MetaCyc: PWY-7343|MetaCyc: PWY-7817 VAPA_1c13720 1102570d106d16008fc67b9c51cbb879 296 Pfam PF00483 Nucleotidyl transferase 15 275 6.7E-26 T 12-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 VAPA_1c13720 1102570d106d16008fc67b9c51cbb879 296 SUPERFAMILY SSF53448 6 276 3.6E-64 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases VAPA_1c29680 0f41a4b74b925304beb988e603a34a8e 319 Pfam PF12697 Alpha/beta hydrolase family 34 310 2.8E-10 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 VAPA_1c29680 0f41a4b74b925304beb988e603a34a8e 319 SUPERFAMILY SSF53474 16 311 3.82E-33 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c29680 0f41a4b74b925304beb988e603a34a8e 319 Gene3D G3DSA:3.40.50.1820 8 317 3.9E-59 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c05290 9bbc54c3289e5f5f9adf3be6f05700d7 423 Pfam PF07690 Major Facilitator Superfamily 31 368 6.4E-28 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 VAPA_1c05290 9bbc54c3289e5f5f9adf3be6f05700d7 423 Gene3D G3DSA:1.20.1250.20 18 412 3.9E-37 T 12-10-2018 VAPA_1c05290 9bbc54c3289e5f5f9adf3be6f05700d7 423 SUPERFAMILY SSF103473 14 414 9.29E-48 T 12-10-2018 IPR036259 MFS transporter superfamily VAPA_1c39760 c8c0d81b553a8b06be04e04d201de63f 238 SUPERFAMILY SSF55729 26 200 1.91E-37 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase VAPA_1c39760 c8c0d81b553a8b06be04e04d201de63f 238 Gene3D G3DSA:3.40.630.30 17 235 4.1E-63 T 12-10-2018 VAPA_1c39760 c8c0d81b553a8b06be04e04d201de63f 238 Pfam PF13302 Acetyltransferase (GNAT) domain 36 176 8.4E-15 T 12-10-2018 IPR000182 GNAT domain VAPA_1c00610 37ad8fb09752b58e647a3596631de845 200 Pfam PF13977 BetI-type transcriptional repressor, C-terminal 119 197 3.6E-6 T 12-10-2018 IPR039538 BetI-type transcriptional repressor, C-terminal VAPA_1c00610 37ad8fb09752b58e647a3596631de845 200 Gene3D G3DSA:1.10.357.10 52 197 1.1E-34 T 12-10-2018 VAPA_1c00610 37ad8fb09752b58e647a3596631de845 200 SUPERFAMILY SSF46689 7 72 2.98E-11 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 VAPA_1c00610 37ad8fb09752b58e647a3596631de845 200 Gene3D G3DSA:1.10.10.60 2 50 3.0E-11 T 12-10-2018 VAPA_1c00610 37ad8fb09752b58e647a3596631de845 200 SUPERFAMILY SSF48498 81 197 3.14E-26 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily VAPA_1c35990 8d212f083a6f6e5e62aedabbda5b83f8 494 Gene3D G3DSA:1.20.1600.10 63 475 2.9E-119 T 12-10-2018 VAPA_1c35990 8d212f083a6f6e5e62aedabbda5b83f8 494 SUPERFAMILY SSF56954 11 477 2.35E-97 T 12-10-2018 VAPA_1c35990 8d212f083a6f6e5e62aedabbda5b83f8 494 Gene3D G3DSA:2.20.200.10 110 363 2.9E-119 T 12-10-2018 VAPA_1c35990 8d212f083a6f6e5e62aedabbda5b83f8 494 Pfam PF02321 Outer membrane efflux protein 296 472 1.0E-17 T 12-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 VAPA_1c35990 8d212f083a6f6e5e62aedabbda5b83f8 494 Pfam PF02321 Outer membrane efflux protein 73 264 2.4E-21 T 12-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 VAPA_1c35990 8d212f083a6f6e5e62aedabbda5b83f8 494 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 20 474 4.4E-122 T 12-10-2018 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0016020|GO:0022857|GO:0055085 VAPA_1c14220 37362420ea289f526bcfad58f319d670 313 SUPERFAMILY SSF161098 93 298 4.84E-20 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c14220 37362420ea289f526bcfad58f319d670 313 Gene3D G3DSA:1.10.3720.10 84 304 4.5E-26 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c14220 37362420ea289f526bcfad58f319d670 313 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 313 1.2E-42 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 VAPA_1c27010 751e98b700a6d5d64bc0814700f07a08 225 PIRSF PIRSF000654 118 222 9.6E-14 T 12-10-2018 VAPA_1c27010 751e98b700a6d5d64bc0814700f07a08 225 PIRSF PIRSF000654 13 95 1.0E-7 T 12-10-2018 VAPA_1c27010 751e98b700a6d5d64bc0814700f07a08 225 PIRSF PIRSF000654 72 122 5.3E-6 T 12-10-2018 VAPA_1c27010 751e98b700a6d5d64bc0814700f07a08 225 SMART SM00248 23 52 900.0 T 12-10-2018 IPR002110 Ankyrin repeat GO:0005515 VAPA_1c27010 751e98b700a6d5d64bc0814700f07a08 225 SMART SM00248 153 182 2.0E-4 T 12-10-2018 IPR002110 Ankyrin repeat GO:0005515 VAPA_1c27010 751e98b700a6d5d64bc0814700f07a08 225 SMART SM00248 56 86 210.0 T 12-10-2018 IPR002110 Ankyrin repeat GO:0005515 VAPA_1c27010 751e98b700a6d5d64bc0814700f07a08 225 SMART SM00248 90 119 0.036 T 12-10-2018 IPR002110 Ankyrin repeat GO:0005515 VAPA_1c27010 751e98b700a6d5d64bc0814700f07a08 225 SMART SM00248 120 149 2.7E-5 T 12-10-2018 IPR002110 Ankyrin repeat GO:0005515 VAPA_1c27010 751e98b700a6d5d64bc0814700f07a08 225 PRINTS PR01415 Ankyrin repeat signature 121 136 9.7E-8 T 12-10-2018 IPR002110 Ankyrin repeat GO:0005515 VAPA_1c27010 751e98b700a6d5d64bc0814700f07a08 225 PRINTS PR01415 Ankyrin repeat signature 169 183 9.7E-8 T 12-10-2018 IPR002110 Ankyrin repeat GO:0005515 VAPA_1c27010 751e98b700a6d5d64bc0814700f07a08 225 SUPERFAMILY SSF48403 29 206 9.23E-47 T 12-10-2018 IPR036770 Ankyrin repeat-containing domain superfamily VAPA_1c27010 751e98b700a6d5d64bc0814700f07a08 225 Pfam PF12796 Ankyrin repeats (3 copies) 72 149 2.0E-15 T 12-10-2018 IPR020683 Ankyrin repeat-containing domain VAPA_1c27010 751e98b700a6d5d64bc0814700f07a08 225 Pfam PF12796 Ankyrin repeats (3 copies) 151 208 4.9E-8 T 12-10-2018 IPR020683 Ankyrin repeat-containing domain VAPA_1c27010 751e98b700a6d5d64bc0814700f07a08 225 Gene3D G3DSA:1.25.40.20 25 215 3.2E-52 T 12-10-2018 IPR036770 Ankyrin repeat-containing domain superfamily VAPA_2c03290 f115ebd64b155803115388a8006a08cc 701 SUPERFAMILY SSF55874 380 557 4.06E-36 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_2c03290 f115ebd64b155803115388a8006a08cc 701 SUPERFAMILY SSF47384 316 387 2.35E-9 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 VAPA_2c03290 f115ebd64b155803115388a8006a08cc 701 PRINTS PR00344 Bacterial sensor protein C-terminal signature 485 499 9.7E-15 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_2c03290 f115ebd64b155803115388a8006a08cc 701 PRINTS PR00344 Bacterial sensor protein C-terminal signature 540 553 9.7E-15 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_2c03290 f115ebd64b155803115388a8006a08cc 701 PRINTS PR00344 Bacterial sensor protein C-terminal signature 516 534 9.7E-15 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_2c03290 f115ebd64b155803115388a8006a08cc 701 PRINTS PR00344 Bacterial sensor protein C-terminal signature 503 513 9.7E-15 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_2c03290 f115ebd64b155803115388a8006a08cc 701 Pfam PF13185 GAF domain 166 305 2.3E-16 T 12-10-2018 IPR003018 GAF domain GO:0005515 VAPA_2c03290 f115ebd64b155803115388a8006a08cc 701 SUPERFAMILY SSF55785 34 148 1.57E-21 T 12-10-2018 IPR035965 PAS domain superfamily VAPA_2c03290 f115ebd64b155803115388a8006a08cc 701 SUPERFAMILY SSF55781 167 317 5.89E-27 T 12-10-2018 VAPA_2c03290 f115ebd64b155803115388a8006a08cc 701 Gene3D G3DSA:3.30.450.20 21 136 3.5E-26 T 12-10-2018 VAPA_2c03290 f115ebd64b155803115388a8006a08cc 701 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 432 554 1.5E-15 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase VAPA_2c03290 f115ebd64b155803115388a8006a08cc 701 Pfam PF00072 Response regulator receiver domain 579 690 8.8E-11 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_2c03290 f115ebd64b155803115388a8006a08cc 701 Pfam PF00512 His Kinase A (phospho-acceptor) domain 323 388 1.6E-8 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 VAPA_2c03290 f115ebd64b155803115388a8006a08cc 701 Gene3D G3DSA:1.10.287.130 317 389 4.1E-17 T 12-10-2018 VAPA_2c03290 f115ebd64b155803115388a8006a08cc 701 SMART SM00065 167 315 4.2E-16 T 12-10-2018 IPR003018 GAF domain GO:0005515 VAPA_2c03290 f115ebd64b155803115388a8006a08cc 701 SMART SM00091 23 89 2.3E-10 T 12-10-2018 IPR000014 PAS domain VAPA_2c03290 f115ebd64b155803115388a8006a08cc 701 SMART SM00388 322 390 6.6E-8 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 VAPA_2c03290 f115ebd64b155803115388a8006a08cc 701 SMART SM00448 577 691 9.7E-9 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_2c03290 f115ebd64b155803115388a8006a08cc 701 Gene3D G3DSA:3.30.450.40 142 316 2.9E-30 T 12-10-2018 IPR029016 GAF-like domain superfamily VAPA_2c03290 f115ebd64b155803115388a8006a08cc 701 Gene3D G3DSA:3.40.50.2300 575 699 1.1E-19 T 12-10-2018 VAPA_2c03290 f115ebd64b155803115388a8006a08cc 701 Pfam PF13426 PAS domain 33 136 7.2E-11 T 12-10-2018 IPR000014 PAS domain VAPA_2c03290 f115ebd64b155803115388a8006a08cc 701 SMART SM00387 431 556 6.0E-25 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase VAPA_2c03290 f115ebd64b155803115388a8006a08cc 701 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 20 139 1.6E-22 T 12-10-2018 IPR000014 PAS domain VAPA_2c03290 f115ebd64b155803115388a8006a08cc 701 Gene3D G3DSA:3.30.565.10 391 558 3.8E-40 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_2c03290 f115ebd64b155803115388a8006a08cc 701 SUPERFAMILY SSF52172 576 696 4.27E-19 T 12-10-2018 IPR011006 CheY-like superfamily VAPA_1c35400 f3dfeeff47231baff000da4f012633af 364 Gene3D G3DSA:3.30.310.170 243 364 2.3E-12 T 12-10-2018 VAPA_1c35400 f3dfeeff47231baff000da4f012633af 364 Pfam PF06804 NlpB/DapX lipoprotein 33 361 2.2E-54 T 12-10-2018 IPR010653 NlpB/DapX lipoprotein VAPA_1c30440 0e1266e393bcc3d18d422501c13fb1de 421 Hamap MF_00175 ATP-dependent Clp protease ATP-binding subunit ClpX [clpX]. 2 416 52.944 T 12-10-2018 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 VAPA_1c30440 0e1266e393bcc3d18d422501c13fb1de 421 SUPERFAMILY SSF57716 13 48 9.55E-12 T 12-10-2018 VAPA_1c30440 0e1266e393bcc3d18d422501c13fb1de 421 Gene3D G3DSA:1.10.8.60 317 421 2.9E-37 T 12-10-2018 VAPA_1c30440 0e1266e393bcc3d18d422501c13fb1de 421 SUPERFAMILY SSF52540 63 402 1.51E-76 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c30440 0e1266e393bcc3d18d422501c13fb1de 421 Pfam PF07724 AAA domain (Cdc48 subfamily) 115 311 3.3E-49 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 VAPA_1c30440 0e1266e393bcc3d18d422501c13fb1de 421 SMART SM00994 12 51 3.2E-24 T 12-10-2018 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 VAPA_1c30440 0e1266e393bcc3d18d422501c13fb1de 421 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 318 394 3.2E-15 T 12-10-2018 IPR019489 Clp ATPase, C-terminal VAPA_1c30440 0e1266e393bcc3d18d422501c13fb1de 421 Gene3D G3DSA:3.40.50.300 58 316 1.1E-109 T 12-10-2018 VAPA_1c30440 0e1266e393bcc3d18d422501c13fb1de 421 Gene3D G3DSA:3.30.50.30 2 52 3.2E-25 T 12-10-2018 IPR038366 Zinc finger, ClpX C4-type superfamily VAPA_1c30440 0e1266e393bcc3d18d422501c13fb1de 421 SMART SM01086 318 412 5.6E-31 T 12-10-2018 IPR019489 Clp ATPase, C-terminal VAPA_1c30440 0e1266e393bcc3d18d422501c13fb1de 421 Pfam PF06689 ClpX C4-type zinc finger 13 49 1.2E-19 T 12-10-2018 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 VAPA_1c30440 0e1266e393bcc3d18d422501c13fb1de 421 TIGRFAM TIGR00382 clpX: ATP-dependent Clp protease, ATP-binding subunit ClpX 10 412 5.4E-203 T 12-10-2018 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 VAPA_1c30440 0e1266e393bcc3d18d422501c13fb1de 421 SMART SM00382 114 267 3.6E-12 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c35150 020241fd8be21bf089b35b3f07976003 460 SUPERFAMILY SSF51905 21 410 4.33E-30 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c35150 020241fd8be21bf089b35b3f07976003 460 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 22 44 8.9E-9 T 12-10-2018 VAPA_1c35150 020241fd8be21bf089b35b3f07976003 460 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 377 392 8.9E-9 T 12-10-2018 VAPA_1c35150 020241fd8be21bf089b35b3f07976003 460 Gene3D G3DSA:3.50.50.60 19 247 1.5E-22 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c35150 020241fd8be21bf089b35b3f07976003 460 Pfam PF12831 FAD dependent oxidoreductase 22 357 5.3E-61 T 12-10-2018 IPR039649 Digeranylgeranylglycerophospholipid reductase, N-terminal VAPA_1c35150 020241fd8be21bf089b35b3f07976003 460 Pfam PF12831 FAD dependent oxidoreductase 360 431 8.0E-22 T 12-10-2018 IPR039649 Digeranylgeranylglycerophospholipid reductase, N-terminal VAPA_1c05820 024448cb522d88a6830fe3b0348638d2 728 Pfam PF01965 DJ-1/PfpI family 561 672 2.4E-11 T 12-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 VAPA_1c05820 024448cb522d88a6830fe3b0348638d2 728 ProSitePatterns PS00437 Catalase proximal heme-ligand signature. 368 376 - T 12-10-2018 IPR002226 Catalase haem-binding site GO:0020037 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 VAPA_1c05820 024448cb522d88a6830fe3b0348638d2 728 SMART SM01060 38 426 1.6E-280 T 12-10-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 VAPA_1c05820 024448cb522d88a6830fe3b0348638d2 728 Gene3D G3DSA:1.20.1370.20 451 555 7.9E-33 T 12-10-2018 VAPA_1c05820 024448cb522d88a6830fe3b0348638d2 728 SUPERFAMILY SSF56634 21 526 7.46E-222 T 12-10-2018 IPR020835 Catalase superfamily GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 VAPA_1c05820 024448cb522d88a6830fe3b0348638d2 728 PIRSF PIRSF038927 4 726 0.0 T 12-10-2018 IPR024712 Catalase, mono-functional, haem-containing, clade 2 GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 VAPA_1c05820 024448cb522d88a6830fe3b0348638d2 728 Pfam PF06628 Catalase-related immune-responsive 454 516 6.4E-23 T 12-10-2018 IPR010582 Catalase immune-responsive domain KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 VAPA_1c05820 024448cb522d88a6830fe3b0348638d2 728 ProSitePatterns PS00438 Catalase proximal active site signature. 74 90 - T 12-10-2018 IPR024708 Catalase active site GO:0004096 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 VAPA_1c05820 024448cb522d88a6830fe3b0348638d2 728 Pfam PF00199 Catalase 38 422 8.8E-183 T 12-10-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 VAPA_1c05820 024448cb522d88a6830fe3b0348638d2 728 Gene3D G3DSA:3.40.50.880 556 724 2.9E-44 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like VAPA_1c05820 024448cb522d88a6830fe3b0348638d2 728 PRINTS PR00067 Catalase signature 114 132 1.8E-72 T 12-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 VAPA_1c05820 024448cb522d88a6830fe3b0348638d2 728 PRINTS PR00067 Catalase signature 135 152 1.8E-72 T 12-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 VAPA_1c05820 024448cb522d88a6830fe3b0348638d2 728 PRINTS PR00067 Catalase signature 51 74 1.8E-72 T 12-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 VAPA_1c05820 024448cb522d88a6830fe3b0348638d2 728 PRINTS PR00067 Catalase signature 355 381 1.8E-72 T 12-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 VAPA_1c05820 024448cb522d88a6830fe3b0348638d2 728 PRINTS PR00067 Catalase signature 154 172 1.8E-72 T 12-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 VAPA_1c05820 024448cb522d88a6830fe3b0348638d2 728 PRINTS PR00067 Catalase signature 323 350 1.8E-72 T 12-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 VAPA_1c05820 024448cb522d88a6830fe3b0348638d2 728 Gene3D G3DSA:2.40.180.10 1 448 1.5E-208 T 12-10-2018 IPR037060 Catalase core domain superfamily GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 VAPA_1c05820 024448cb522d88a6830fe3b0348638d2 728 SUPERFAMILY SSF52317 558 720 1.74E-20 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like VAPA_1c34680 27186582c23aefb4d93f840e03027fbb 310 SMART SM00893 3 182 2.3E-58 T 12-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 VAPA_1c34680 27186582c23aefb4d93f840e03027fbb 310 SUPERFAMILY SSF52467 189 310 2.73E-44 T 12-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily VAPA_1c34680 27186582c23aefb4d93f840e03027fbb 310 Gene3D G3DSA:3.40.50.620 3 183 2.7E-55 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold VAPA_1c34680 27186582c23aefb4d93f840e03027fbb 310 Pfam PF00766 Electron transfer flavoprotein FAD-binding domain 190 273 7.9E-34 T 12-10-2018 IPR014731 Electron transfer flavoprotein, alpha subunit, C-terminal Reactome: R-HSA-611105 VAPA_1c34680 27186582c23aefb4d93f840e03027fbb 310 Pfam PF01012 Electron transfer flavoprotein domain 4 168 8.0E-41 T 12-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 VAPA_1c34680 27186582c23aefb4d93f840e03027fbb 310 PIRSF PIRSF000089 1 310 1.8E-105 T 12-10-2018 IPR001308 Electron transfer flavoprotein alpha subunit/FixB GO:0009055|GO:0050660 Reactome: R-HSA-611105 VAPA_1c34680 27186582c23aefb4d93f840e03027fbb 310 ProSitePatterns PS00696 Electron transfer flavoprotein alpha-subunit signature. 254 280 - T 12-10-2018 IPR018206 Electron transfer flavoprotein subunit alpha, conserved site Reactome: R-HSA-611105 VAPA_1c34680 27186582c23aefb4d93f840e03027fbb 310 Gene3D G3DSA:3.40.50.1220 184 310 6.3E-55 T 12-10-2018 VAPA_1c34680 27186582c23aefb4d93f840e03027fbb 310 SUPERFAMILY SSF52402 3 186 9.07E-57 T 12-10-2018 VAPA_1c33920 0cd30e238654d1d21e1d60b5003fd533 189 SUPERFAMILY SSF48317 2 163 4.71E-25 T 12-10-2018 IPR036938 Phosphatidic acid phosphatase type 2/haloperoxidase superfamily VAPA_1c33920 0cd30e238654d1d21e1d60b5003fd533 189 SMART SM00014 51 163 4.3E-10 T 12-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase VAPA_1c33920 0cd30e238654d1d21e1d60b5003fd533 189 Pfam PF01569 PAP2 superfamily 57 163 3.9E-16 T 12-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase VAPA_1c33920 0cd30e238654d1d21e1d60b5003fd533 189 Gene3D G3DSA:1.20.144.10 88 179 1.9E-14 T 12-10-2018 VAPA_1c40270 883febb6f315ef9b0b8115f49c087825 539 Gene3D G3DSA:3.30.465.10 287 399 6.0E-29 T 12-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 VAPA_1c40270 883febb6f315ef9b0b8115f49c087825 539 Gene3D G3DSA:3.30.43.10 233 282 1.8E-18 T 12-10-2018 IPR016167 FAD-binding, type PCMH, subdomain 1 VAPA_1c40270 883febb6f315ef9b0b8115f49c087825 539 TIGRFAM TIGR02963 xanthine_xdhA: xanthine dehydrogenase, small subunit 14 510 9.2E-202 T 12-10-2018 IPR014307 Xanthine dehydrogenase, small subunit GO:0004854|GO:0004855|GO:0050660|GO:0055114 KEGG: 00230+1.17.1.4|MetaCyc: PWY-5497|MetaCyc: PWY-5695|MetaCyc: PWY-6538|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-6999|Reactome: R-HSA-74259|Reactome: R-HSA-8851680 VAPA_1c40270 883febb6f315ef9b0b8115f49c087825 539 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 21 71 6.1E-4 T 12-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 VAPA_1c40270 883febb6f315ef9b0b8115f49c087825 539 Pfam PF03450 CO dehydrogenase flavoprotein C-terminal domain 407 509 1.9E-32 T 12-10-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal VAPA_1c40270 883febb6f315ef9b0b8115f49c087825 539 Gene3D G3DSA:3.10.20.30 10 108 6.9E-26 T 12-10-2018 IPR012675 Beta-grasp domain superfamily VAPA_1c40270 883febb6f315ef9b0b8115f49c087825 539 Pfam PF01799 [2Fe-2S] binding domain 101 190 6.2E-28 T 12-10-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 VAPA_1c40270 883febb6f315ef9b0b8115f49c087825 539 SMART SM01092 407 510 9.3E-37 T 12-10-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal VAPA_1c40270 883febb6f315ef9b0b8115f49c087825 539 SUPERFAMILY SSF56176 230 399 2.52E-46 T 12-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 VAPA_1c40270 883febb6f315ef9b0b8115f49c087825 539 SUPERFAMILY SSF47741 122 204 1.57E-30 T 12-10-2018 IPR036884 [2Fe-2S]-binding domain superfamily VAPA_1c40270 883febb6f315ef9b0b8115f49c087825 539 SUPERFAMILY SSF54292 13 105 3.19E-17 T 12-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 VAPA_1c40270 883febb6f315ef9b0b8115f49c087825 539 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 232 399 2.0E-45 T 12-10-2018 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 VAPA_1c40270 883febb6f315ef9b0b8115f49c087825 539 Gene3D G3DSA:1.10.150.120 121 196 1.5E-31 T 12-10-2018 VAPA_1c40270 883febb6f315ef9b0b8115f49c087825 539 PIRSF PIRSF036557 11 523 2.4E-226 T 12-10-2018 IPR012175 Xanthine dehydrogenase, small subunit, bacteria VAPA_1c40270 883febb6f315ef9b0b8115f49c087825 539 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 51 59 - T 12-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 VAPA_1c40270 883febb6f315ef9b0b8115f49c087825 539 SUPERFAMILY SSF55447 405 512 1.44E-34 T 12-10-2018 IPR036683 CO dehydrogenase flavoprotein, C-terminal domain superfamily VAPA_1c40270 883febb6f315ef9b0b8115f49c087825 539 Gene3D G3DSA:3.30.390.50 407 511 4.3E-28 T 12-10-2018 VAPA_1c23360 12c30ff27c1012fdf802e75d158d8f5a 685 Gene3D G3DSA:1.10.1370.40 17 676 4.5E-242 T 12-10-2018 VAPA_1c23360 12c30ff27c1012fdf802e75d158d8f5a 685 Pfam PF01432 Peptidase family M3 221 678 6.1E-136 T 12-10-2018 IPR001567 Peptidase M3A/M3B catalytic domain GO:0004222|GO:0006508 VAPA_1c23360 12c30ff27c1012fdf802e75d158d8f5a 685 Gene3D G3DSA:1.10.1370.10 139 607 4.5E-242 T 12-10-2018 IPR024077 Neurolysin/Thimet oligopeptidase, domain 2 VAPA_1c23360 12c30ff27c1012fdf802e75d158d8f5a 685 SUPERFAMILY SSF55486 5 678 1.26E-178 T 12-10-2018 VAPA_1c15770 732406dbf87f7b580cb28b8ba6729a0b 357 Gene3D G3DSA:3.40.50.720 1 190 1.2E-52 T 12-10-2018 VAPA_1c15770 732406dbf87f7b580cb28b8ba6729a0b 357 SUPERFAMILY SSF48179 184 353 1.33E-36 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 VAPA_1c15770 732406dbf87f7b580cb28b8ba6729a0b 357 SUPERFAMILY SSF51735 1 177 1.42E-19 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c15770 732406dbf87f7b580cb28b8ba6729a0b 357 Pfam PF02317 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain 182 321 4.6E-22 T 12-10-2018 IPR003421 Opine dehydrogenase GO:0016491|GO:0050662|GO:0055114 VAPA_1c15770 732406dbf87f7b580cb28b8ba6729a0b 357 Gene3D G3DSA:1.10.1040.10 192 342 9.5E-30 T 12-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 VAPA_1c15770 732406dbf87f7b580cb28b8ba6729a0b 357 Pfam PF01210 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 2 98 8.0E-7 T 12-10-2018 IPR011128 Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal GO:0016616|GO:0046168|GO:0051287|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 VAPA_1c53100 41c99b9dbd627424ec771d682b60e74f 627 Hamap MF_01463_B Protein translocase subunit SecD [secD]. 2 610 47.166 T 12-10-2018 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 VAPA_1c53100 41c99b9dbd627424ec771d682b60e74f 627 Pfam PF02355 Protein export membrane protein 427 599 2.7E-21 T 12-10-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial VAPA_1c53100 41c99b9dbd627424ec771d682b60e74f 627 SUPERFAMILY SSF82866 405 602 3.27E-39 T 12-10-2018 VAPA_1c53100 41c99b9dbd627424ec771d682b60e74f 627 Gene3D G3DSA:3.30.1360.200 285 426 8.8E-53 T 12-10-2018 VAPA_1c53100 41c99b9dbd627424ec771d682b60e74f 627 Pfam PF07549 SecD/SecF GG Motif 121 144 4.1E-4 T 12-10-2018 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site VAPA_1c53100 41c99b9dbd627424ec771d682b60e74f 627 Gene3D G3DSA:3.30.70.3400 230 431 8.8E-53 T 12-10-2018 VAPA_1c53100 41c99b9dbd627424ec771d682b60e74f 627 Gene3D G3DSA:1.20.1640.10 449 599 5.2E-7 T 12-10-2018 VAPA_1c53100 41c99b9dbd627424ec771d682b60e74f 627 Pfam PF13721 SecD export protein N-terminal TM region 1 108 1.5E-36 T 12-10-2018 IPR027398 SecD export protein N-terminal TM domain VAPA_1c53100 41c99b9dbd627424ec771d682b60e74f 627 TIGRFAM TIGR01129 secD: protein-export membrane protein SecD 128 595 8.6E-140 T 12-10-2018 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 VAPA_1c53100 41c99b9dbd627424ec771d682b60e74f 627 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 356 588 5.9E-72 T 12-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial VAPA_1c42970 daa58c9cefa016c633895391ebdaf3bd 781 Pfam PF00448 SRP54-type protein, GTPase domain 189 380 3.4E-35 T 12-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 VAPA_1c42970 daa58c9cefa016c633895391ebdaf3bd 781 Gene3D G3DSA:3.40.50.300 181 370 9.5E-52 T 12-10-2018 VAPA_1c42970 daa58c9cefa016c633895391ebdaf3bd 781 Gene3D G3DSA:1.20.120.1380 163 373 9.5E-52 T 12-10-2018 VAPA_1c42970 daa58c9cefa016c633895391ebdaf3bd 781 SMART SM00382 186 355 3.6E-7 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c42970 daa58c9cefa016c633895391ebdaf3bd 781 SMART SM00962 187 382 1.6E-51 T 12-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 VAPA_1c42970 daa58c9cefa016c633895391ebdaf3bd 781 SUPERFAMILY SSF52540 182 378 2.63E-30 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c42970 daa58c9cefa016c633895391ebdaf3bd 781 TIGRFAM TIGR03499 FlhF: flagellar biosynthesis protein FlhF 12 275 6.1E-76 T 12-10-2018 IPR020006 Flagellar biosynthesis protein FlhF GO:0003924|GO:0044781 VAPA_1c34410 97869c42d66d1f0d5733a644783d69df 328 PIRSF PIRSF017082 1 327 7.8E-72 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c34410 97869c42d66d1f0d5733a644783d69df 328 Gene3D G3DSA:3.40.190.150 34 317 4.0E-104 T 12-10-2018 VAPA_1c34410 97869c42d66d1f0d5733a644783d69df 328 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 53 323 5.2E-78 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c34410 97869c42d66d1f0d5733a644783d69df 328 Gene3D G3DSA:3.40.190.10 132 252 4.0E-104 T 12-10-2018 VAPA_1c34410 97869c42d66d1f0d5733a644783d69df 328 SUPERFAMILY SSF53850 120 288 5.1E-9 T 12-10-2018 VAPA_1c25130 4c54e29cc85b0773e9b47c52c284f54b 512 Pfam PF08502 LeuA allosteric (dimerisation) domain 371 501 2.9E-34 T 12-10-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 VAPA_1c25130 4c54e29cc85b0773e9b47c52c284f54b 512 SMART SM00917 371 502 3.7E-40 T 12-10-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 VAPA_1c25130 4c54e29cc85b0773e9b47c52c284f54b 512 TIGRFAM TIGR00973 leuA_bact: 2-isopropylmalate synthase 5 499 3.4E-210 T 12-10-2018 IPR005671 2-isopropylmalate synthase, bacterial-type GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 VAPA_1c25130 4c54e29cc85b0773e9b47c52c284f54b 512 SUPERFAMILY SSF51569 1 292 2.56E-98 T 12-10-2018 VAPA_1c25130 4c54e29cc85b0773e9b47c52c284f54b 512 Gene3D G3DSA:3.20.20.70 2 277 1.2E-108 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 VAPA_1c25130 4c54e29cc85b0773e9b47c52c284f54b 512 SUPERFAMILY SSF110921 394 501 1.96E-27 T 12-10-2018 IPR036230 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain superfamily KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 VAPA_1c25130 4c54e29cc85b0773e9b47c52c284f54b 512 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 12 28 - T 12-10-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 VAPA_1c25130 4c54e29cc85b0773e9b47c52c284f54b 512 Hamap MF_01025 2-isopropylmalate synthase [leuA]. 2 511 41.913 T 12-10-2018 IPR005671 2-isopropylmalate synthase, bacterial-type GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 VAPA_1c25130 4c54e29cc85b0773e9b47c52c284f54b 512 Gene3D G3DSA:3.30.160.270 394 502 1.1E-13 T 12-10-2018 VAPA_1c25130 4c54e29cc85b0773e9b47c52c284f54b 512 ProSitePatterns PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2. 199 212 - T 12-10-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 VAPA_1c25130 4c54e29cc85b0773e9b47c52c284f54b 512 Gene3D G3DSA:1.10.238.260 281 393 3.5E-33 T 12-10-2018 VAPA_1c25130 4c54e29cc85b0773e9b47c52c284f54b 512 Pfam PF00682 HMGL-like 5 274 1.3E-96 T 12-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 VAPA_1c41200 f265e769d29350db4187895eff706c04 288 Gene3D G3DSA:1.10.10.10 1 89 3.1E-23 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c41200 f265e769d29350db4187895eff706c04 288 Pfam PF03466 LysR substrate binding domain 85 284 3.6E-42 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_1c41200 f265e769d29350db4187895eff706c04 288 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 4.2E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c41200 f265e769d29350db4187895eff706c04 288 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 4.2E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c41200 f265e769d29350db4187895eff706c04 288 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 4.2E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c41200 f265e769d29350db4187895eff706c04 288 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 61 8.6E-18 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c41200 f265e769d29350db4187895eff706c04 288 Gene3D G3DSA:3.40.190.10 90 273 7.2E-34 T 12-10-2018 VAPA_1c41200 f265e769d29350db4187895eff706c04 288 SUPERFAMILY SSF46785 1 109 5.2E-21 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c41200 f265e769d29350db4187895eff706c04 288 Gene3D G3DSA:3.40.190.10 162 261 7.2E-34 T 12-10-2018 VAPA_1c41200 f265e769d29350db4187895eff706c04 288 SUPERFAMILY SSF53850 86 278 1.07E-36 T 12-10-2018 VAPA_1c41960 a3c0a92a142d4c1bdb41b64e9e9965a2 137 Pfam PF03626 Prokaryotic Cytochrome C oxidase subunit IV 38 110 6.8E-18 T 12-10-2018 IPR005171 Cytochrome C oxidase subunit IV, prokaryotes GO:0016021 VAPA_1c41960 a3c0a92a142d4c1bdb41b64e9e9965a2 137 TIGRFAM TIGR02847 CyoD: cytochrome o ubiquinol oxidase subunit IV 31 126 2.4E-33 T 12-10-2018 IPR014210 Cytochrome o ubiquinol oxidase subunit IV GO:0008827|GO:0015990|GO:0016021 VAPA_1c47770 1f6759adef8f7230b40568800416dae9 224 Gene3D G3DSA:3.40.30.10 1 84 4.3E-31 T 12-10-2018 VAPA_1c47770 1f6759adef8f7230b40568800416dae9 224 SUPERFAMILY SSF52833 1 85 1.27E-17 T 12-10-2018 IPR036249 Thioredoxin-like superfamily VAPA_1c47770 1f6759adef8f7230b40568800416dae9 224 Pfam PF13417 Glutathione S-transferase, N-terminal domain 12 80 6.8E-12 T 12-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 VAPA_1c47770 1f6759adef8f7230b40568800416dae9 224 Pfam PF00043 Glutathione S-transferase, C-terminal domain 125 208 1.5E-9 T 12-10-2018 IPR004046 Glutathione S-transferase, C-terminal VAPA_1c47770 1f6759adef8f7230b40568800416dae9 224 Gene3D G3DSA:1.20.1050.10 85 213 3.8E-30 T 12-10-2018 VAPA_1c47770 1f6759adef8f7230b40568800416dae9 224 SUPERFAMILY SSF47616 82 218 3.9E-23 T 12-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily VAPA_2c09750 703617c27987fb70e6d99d7eb8de68b6 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 1.7E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_2c09750 703617c27987fb70e6d99d7eb8de68b6 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 1.7E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_2c09750 703617c27987fb70e6d99d7eb8de68b6 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 1.7E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_2c09750 703617c27987fb70e6d99d7eb8de68b6 299 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 3.1E-18 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_2c09750 703617c27987fb70e6d99d7eb8de68b6 299 Gene3D G3DSA:1.10.10.10 1 81 3.7E-21 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_2c09750 703617c27987fb70e6d99d7eb8de68b6 299 Gene3D G3DSA:3.40.190.10 167 269 8.9E-31 T 12-10-2018 VAPA_2c09750 703617c27987fb70e6d99d7eb8de68b6 299 SUPERFAMILY SSF46785 3 112 1.14E-19 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_2c09750 703617c27987fb70e6d99d7eb8de68b6 299 SUPERFAMILY SSF53850 91 297 2.9E-29 T 12-10-2018 VAPA_2c09750 703617c27987fb70e6d99d7eb8de68b6 299 Gene3D G3DSA:3.40.190.10 95 286 8.9E-31 T 12-10-2018 VAPA_2c09750 703617c27987fb70e6d99d7eb8de68b6 299 Pfam PF03466 LysR substrate binding domain 89 295 2.4E-28 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_1c02390 257648e3ed241d1d629dcc123b5e8be9 349 Gene3D G3DSA:2.160.20.80 171 343 7.9E-30 T 12-10-2018 VAPA_1c02390 257648e3ed241d1d629dcc123b5e8be9 349 Pfam PF13599 Pentapeptide repeats (9 copies) 80 153 7.0E-7 T 12-10-2018 IPR001646 Pentapeptide repeat VAPA_1c02390 257648e3ed241d1d629dcc123b5e8be9 349 SUPERFAMILY SSF141571 7 166 1.18E-31 T 12-10-2018 VAPA_1c02390 257648e3ed241d1d629dcc123b5e8be9 349 SUPERFAMILY SSF141571 149 318 7.85E-34 T 12-10-2018 VAPA_1c02390 257648e3ed241d1d629dcc123b5e8be9 349 Gene3D G3DSA:2.160.20.100 76 170 1.4E-13 T 12-10-2018 VAPA_1c02390 257648e3ed241d1d629dcc123b5e8be9 349 Gene3D G3DSA:2.160.20.100 7 75 2.9E-13 T 12-10-2018 VAPA_1c02390 257648e3ed241d1d629dcc123b5e8be9 349 Pfam PF00805 Pentapeptide repeats (8 copies) 291 319 4.1E-6 T 12-10-2018 IPR001646 Pentapeptide repeat VAPA_1c02390 257648e3ed241d1d629dcc123b5e8be9 349 Pfam PF00805 Pentapeptide repeats (8 copies) 23 54 6.5E-8 T 12-10-2018 IPR001646 Pentapeptide repeat VAPA_1c02390 257648e3ed241d1d629dcc123b5e8be9 349 Pfam PF00805 Pentapeptide repeats (8 copies) 191 228 7.2E-12 T 12-10-2018 IPR001646 Pentapeptide repeat VAPA_1c09120 c35275738c9361de0b06fe8f79e883de 341 Pfam PF00005 ABC transporter 33 191 2.3E-25 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c09120 c35275738c9361de0b06fe8f79e883de 341 Gene3D G3DSA:3.40.50.300 11 336 2.6E-94 T 12-10-2018 VAPA_1c09120 c35275738c9361de0b06fe8f79e883de 341 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 243 308 4.1E-16 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 VAPA_1c09120 c35275738c9361de0b06fe8f79e883de 341 SUPERFAMILY SSF52540 12 262 8.42E-66 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c09120 c35275738c9361de0b06fe8f79e883de 341 SMART SM00382 41 249 4.5E-15 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c09120 c35275738c9361de0b06fe8f79e883de 341 ProSitePatterns PS00211 ABC transporters family signature. 164 178 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_1c09120 c35275738c9361de0b06fe8f79e883de 341 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 241 327 2.2E-23 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 VAPA_1c10390 228aca8555dec515fa16c0ed4b2c7819 461 Gene3D G3DSA:3.40.50.2000 232 440 4.4E-160 T 12-10-2018 VAPA_1c10390 228aca8555dec515fa16c0ed4b2c7819 461 Gene3D G3DSA:3.40.50.2000 17 451 4.4E-160 T 12-10-2018 VAPA_1c10390 228aca8555dec515fa16c0ed4b2c7819 461 Pfam PF00982 Glycosyltransferase family 20 16 455 4.7E-131 T 12-10-2018 IPR001830 Glycosyl transferase, family 20 GO:0003824|GO:0005992 KEGG: 00500+2.4.1.15 VAPA_1c10390 228aca8555dec515fa16c0ed4b2c7819 461 SUPERFAMILY SSF53756 2 457 1.32E-148 T 12-10-2018 VAPA_1c10390 228aca8555dec515fa16c0ed4b2c7819 461 TIGRFAM TIGR02400 trehalose_OtsA: alpha,alpha-trehalose-phosphate synthase (UDP-forming) 3 455 7.4E-174 T 12-10-2018 IPR012766 Alpha,alpha-trehalose-phosphate synthase GO:0003825|GO:0005992 KEGG: 00500+2.4.1.15 VAPA_1c41870 86d436265b21d3fcf9a955b859acf7d8 231 Gene3D G3DSA:1.10.3720.10 5 227 1.4E-48 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c41870 86d436265b21d3fcf9a955b859acf7d8 231 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 37 225 4.2E-18 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 VAPA_1c41870 86d436265b21d3fcf9a955b859acf7d8 231 SUPERFAMILY SSF161098 16 212 9.94E-41 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c41870 86d436265b21d3fcf9a955b859acf7d8 231 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 17 121 4.0E-17 T 12-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 VAPA_1c51690 e71f29423099197c2a2575417a13bdb8 336 Gene3D G3DSA:3.40.50.720 145 285 5.2E-99 T 12-10-2018 VAPA_1c51690 e71f29423099197c2a2575417a13bdb8 336 SUPERFAMILY SSF50129 11 169 1.83E-37 T 12-10-2018 IPR011032 GroES-like superfamily VAPA_1c51690 e71f29423099197c2a2575417a13bdb8 336 SUPERFAMILY SSF51735 136 300 4.76E-43 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c51690 e71f29423099197c2a2575417a13bdb8 336 Gene3D G3DSA:3.90.180.10 24 328 5.2E-99 T 12-10-2018 VAPA_1c51690 e71f29423099197c2a2575417a13bdb8 336 Pfam PF00107 Zinc-binding dehydrogenase 174 297 2.3E-25 T 12-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 VAPA_1c51690 e71f29423099197c2a2575417a13bdb8 336 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 32 95 1.1E-11 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 VAPA_1c51690 e71f29423099197c2a2575417a13bdb8 336 SMART SM00829 13 334 2.6E-28 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 VAPA_1c20310 af9c55b40982ce6c031d4bf3554e9de6 322 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 45 318 2.3E-64 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c20310 af9c55b40982ce6c031d4bf3554e9de6 322 Gene3D G3DSA:3.40.190.10 123 246 2.9E-89 T 12-10-2018 VAPA_1c20310 af9c55b40982ce6c031d4bf3554e9de6 322 SUPERFAMILY SSF53850 109 279 2.27E-11 T 12-10-2018 VAPA_1c20310 af9c55b40982ce6c031d4bf3554e9de6 322 Gene3D G3DSA:3.40.190.150 27 293 2.9E-89 T 12-10-2018 VAPA_1c20310 af9c55b40982ce6c031d4bf3554e9de6 322 PIRSF PIRSF017082 1 316 2.9E-62 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c16040 c7f50f00f3255189bb3f7a31eae60cb5 152 Gene3D G3DSA:3.10.129.10 2 147 2.2E-32 T 12-10-2018 VAPA_1c16040 c7f50f00f3255189bb3f7a31eae60cb5 152 Pfam PF13279 Thioesterase-like superfamily 22 143 2.4E-9 T 12-10-2018 VAPA_1c16040 c7f50f00f3255189bb3f7a31eae60cb5 152 SUPERFAMILY SSF54637 11 146 7.25E-36 T 12-10-2018 IPR029069 HotDog domain superfamily VAPA_1c48550 db8dff0ff2dd023d192a8f75205c30e3 492 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 291 302 - T 12-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 VAPA_1c48550 db8dff0ff2dd023d192a8f75205c30e3 492 Gene3D G3DSA:3.40.605.10 27 480 9.5E-179 T 12-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 VAPA_1c48550 db8dff0ff2dd023d192a8f75205c30e3 492 Gene3D G3DSA:3.40.309.10 270 457 9.5E-179 T 12-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 VAPA_1c48550 db8dff0ff2dd023d192a8f75205c30e3 492 SUPERFAMILY SSF53720 12 489 2.23E-166 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 VAPA_1c48550 db8dff0ff2dd023d192a8f75205c30e3 492 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 263 270 - T 12-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 VAPA_1c48550 db8dff0ff2dd023d192a8f75205c30e3 492 Pfam PF00171 Aldehyde dehydrogenase family 27 484 9.9E-166 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 VAPA_1c48550 db8dff0ff2dd023d192a8f75205c30e3 492 TIGRFAM TIGR01780 SSADH: succinate-semialdehyde dehydrogenase 36 483 8.2E-211 T 12-10-2018 IPR010102 Succinate semialdehyde dehydrogenase GO:0009013|GO:0009450|GO:0055114 Reactome: R-HSA-916853 VAPA_2c09240 e3cfe152fbc387609899cd4cab9393c0 328 PIRSF PIRSF017082 3 328 4.4E-64 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_2c09240 e3cfe152fbc387609899cd4cab9393c0 328 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 51 322 3.2E-76 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_2c09240 e3cfe152fbc387609899cd4cab9393c0 328 Gene3D G3DSA:3.40.190.150 32 317 9.2E-97 T 12-10-2018 VAPA_2c09240 e3cfe152fbc387609899cd4cab9393c0 328 Gene3D G3DSA:3.40.190.10 130 253 9.2E-97 T 12-10-2018 VAPA_2c09240 e3cfe152fbc387609899cd4cab9393c0 328 SUPERFAMILY SSF53850 117 291 3.53E-12 T 12-10-2018 VAPA_1c30720 a55d6a93707bfad38dd3a402a20824c4 308 Gene3D G3DSA:1.10.101.10 1 77 1.5E-17 T 12-10-2018 IPR036366 PGBD superfamily Reactome: R-HSA-1442490|Reactome: R-HSA-1474228 VAPA_1c30720 a55d6a93707bfad38dd3a402a20824c4 308 SUPERFAMILY SSF47090 3 71 1.83E-12 T 12-10-2018 IPR036365 PGBD-like superfamily VAPA_1c30720 a55d6a93707bfad38dd3a402a20824c4 308 Pfam PF01471 Putative peptidoglycan binding domain 11 70 1.3E-11 T 12-10-2018 IPR002477 Peptidoglycan binding-like VAPA_1c26020 3a2e64beac46ac612be166560eb8c052 694 Pfam PF12826 Helix-hairpin-helix motif 531 594 5.2E-27 T 12-10-2018 VAPA_1c26020 3a2e64beac46ac612be166560eb8c052 694 Gene3D G3DSA:1.10.150.20 453 525 1.3E-26 T 12-10-2018 VAPA_1c26020 3a2e64beac46ac612be166560eb8c052 694 Gene3D G3DSA:3.30.470.90 71 334 7.9E-92 T 12-10-2018 VAPA_1c26020 3a2e64beac46ac612be166560eb8c052 694 SUPERFAMILY SSF50249 335 411 9.08E-27 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold VAPA_1c26020 3a2e64beac46ac612be166560eb8c052 694 Pfam PF01653 NAD-dependent DNA ligase adenylation domain 7 335 1.2E-114 T 12-10-2018 IPR013839 NAD-dependent DNA ligase, adenylation GO:0003911 VAPA_1c26020 3a2e64beac46ac612be166560eb8c052 694 Hamap MF_01588 DNA ligase [ligA]. 5 688 52.961 T 12-10-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 VAPA_1c26020 3a2e64beac46ac612be166560eb8c052 694 Pfam PF00533 BRCA1 C Terminus (BRCT) domain 614 685 6.4E-12 T 12-10-2018 IPR001357 BRCT domain VAPA_1c26020 3a2e64beac46ac612be166560eb8c052 694 SUPERFAMILY SSF47781 425 605 1.15E-62 T 12-10-2018 IPR010994 RuvA domain 2-like VAPA_1c26020 3a2e64beac46ac612be166560eb8c052 694 Pfam PF03119 NAD-dependent DNA ligase C4 zinc finger domain 428 455 6.0E-12 T 12-10-2018 IPR004149 Zinc-finger, NAD-dependent DNA ligase C4-type GO:0003911|GO:0006260|GO:0006281 VAPA_1c26020 3a2e64beac46ac612be166560eb8c052 694 SUPERFAMILY SSF52113 614 691 2.24E-19 T 12-10-2018 IPR036420 BRCT domain superfamily VAPA_1c26020 3a2e64beac46ac612be166560eb8c052 694 Gene3D G3DSA:3.40.50.10190 605 690 8.6E-29 T 12-10-2018 IPR036420 BRCT domain superfamily VAPA_1c26020 3a2e64beac46ac612be166560eb8c052 694 Gene3D G3DSA:1.10.287.610 1 70 9.6E-28 T 12-10-2018 VAPA_1c26020 3a2e64beac46ac612be166560eb8c052 694 SMART SM00278 565 584 19.0 T 12-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 VAPA_1c26020 3a2e64beac46ac612be166560eb8c052 694 SMART SM00278 501 520 250.0 T 12-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 VAPA_1c26020 3a2e64beac46ac612be166560eb8c052 694 SMART SM00278 467 486 90.0 T 12-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 VAPA_1c26020 3a2e64beac46ac612be166560eb8c052 694 Gene3D G3DSA:2.20.70.80 413 452 5.6E-14 T 12-10-2018 VAPA_1c26020 3a2e64beac46ac612be166560eb8c052 694 Pfam PF03120 NAD-dependent DNA ligase OB-fold domain 339 411 4.2E-33 T 12-10-2018 IPR004150 NAD-dependent DNA ligase, OB-fold GO:0003911|GO:0006260|GO:0006281 VAPA_1c26020 3a2e64beac46ac612be166560eb8c052 694 Gene3D G3DSA:2.40.50.140 335 407 5.2E-32 T 12-10-2018 VAPA_1c26020 3a2e64beac46ac612be166560eb8c052 694 ProSitePatterns PS01056 NAD-dependent DNA ligase signature 2. 348 363 - T 12-10-2018 IPR033136 NAD-dependent DNA ligase, conserved site VAPA_1c26020 3a2e64beac46ac612be166560eb8c052 694 ProSitePatterns PS01055 NAD-dependent DNA ligase signature 1. 123 152 - T 12-10-2018 IPR018239 NAD-dependent DNA ligase, active site VAPA_1c26020 3a2e64beac46ac612be166560eb8c052 694 SUPERFAMILY SSF56091 4 333 1.55E-108 T 12-10-2018 VAPA_1c26020 3a2e64beac46ac612be166560eb8c052 694 SMART SM00532 6 469 7.5E-241 T 12-10-2018 IPR013840 NAD-dependent DNA ligase, N-terminal GO:0003911 VAPA_1c26020 3a2e64beac46ac612be166560eb8c052 694 PIRSF PIRSF001604 1 692 1.3E-234 T 12-10-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 VAPA_1c26020 3a2e64beac46ac612be166560eb8c052 694 SMART SM00292 614 691 5.1E-16 T 12-10-2018 IPR001357 BRCT domain VAPA_1c26020 3a2e64beac46ac612be166560eb8c052 694 Gene3D G3DSA:1.10.150.20 526 604 2.7E-31 T 12-10-2018 VAPA_1c26020 3a2e64beac46ac612be166560eb8c052 694 TIGRFAM TIGR00575 dnlj: DNA ligase, NAD-dependent 14 683 6.8E-244 T 12-10-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 VAPA_1c18760 a173a0f926b5d37aab598a0a1723c63a 636 SUPERFAMILY SSF54534 261 370 1.37E-33 T 12-10-2018 VAPA_1c18760 a173a0f926b5d37aab598a0a1723c63a 636 Pfam PF13616 PPIC-type PPIASE domain 258 368 6.1E-32 T 12-10-2018 VAPA_1c18760 a173a0f926b5d37aab598a0a1723c63a 636 SUPERFAMILY SSF109998 41 239 1.28E-24 T 12-10-2018 IPR027304 Trigger factor/SurA domain superfamily VAPA_1c18760 a173a0f926b5d37aab598a0a1723c63a 636 Gene3D G3DSA:3.10.50.40 257 405 1.6E-39 T 12-10-2018 VAPA_1c18760 a173a0f926b5d37aab598a0a1723c63a 636 Gene3D G3DSA:1.10.4030.30 40 164 1.8E-7 T 12-10-2018 VAPA_1c18760 a173a0f926b5d37aab598a0a1723c63a 636 Pfam PF13624 SurA N-terminal domain 1 162 3.6E-34 T 12-10-2018 VAPA_1c15840 d0bf8c214848d9255e39b45421877d9f 330 SUPERFAMILY SSF63380 4 112 2.08E-21 T 12-10-2018 IPR017938 Riboflavin synthase-like beta-barrel VAPA_1c15840 d0bf8c214848d9255e39b45421877d9f 330 SUPERFAMILY SSF54292 223 328 8.39E-27 T 12-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 VAPA_1c15840 d0bf8c214848d9255e39b45421877d9f 330 Gene3D G3DSA:2.40.30.10 3 113 4.2E-24 T 12-10-2018 VAPA_1c15840 d0bf8c214848d9255e39b45421877d9f 330 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 251 321 9.7E-9 T 12-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 VAPA_1c15840 d0bf8c214848d9255e39b45421877d9f 330 Gene3D G3DSA:3.10.20.30 236 330 3.1E-24 T 12-10-2018 IPR012675 Beta-grasp domain superfamily VAPA_1c15840 d0bf8c214848d9255e39b45421877d9f 330 SUPERFAMILY SSF52343 110 236 2.49E-26 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain VAPA_1c15840 d0bf8c214848d9255e39b45421877d9f 330 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 279 287 - T 12-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 VAPA_1c15840 d0bf8c214848d9255e39b45421877d9f 330 Gene3D G3DSA:3.40.50.80 114 233 5.2E-22 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain VAPA_1c15840 d0bf8c214848d9255e39b45421877d9f 330 Pfam PF00970 Oxidoreductase FAD-binding domain 10 114 2.2E-6 T 12-10-2018 IPR008333 Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain Reactome: R-HSA-1237044 VAPA_1c41500 a9fa7fd1612d7633c8a070d68329c2da 256 SUPERFAMILY SSF51695 1 252 7.12E-49 T 12-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 VAPA_1c41500 a9fa7fd1612d7633c8a070d68329c2da 256 Gene3D G3DSA:3.20.20.190 1 255 9.6E-58 T 12-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 VAPA_1c41500 a9fa7fd1612d7633c8a070d68329c2da 256 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 6 246 4.1E-26 T 12-10-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 VAPA_1c18200 32e51ee170cf4b15d3a0f266f3ed52c9 452 Gene3D G3DSA:3.20.20.120 146 406 1.2E-174 T 12-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily VAPA_1c18200 32e51ee170cf4b15d3a0f266f3ed52c9 452 SUPERFAMILY SSF54826 15 144 1.14E-32 T 12-10-2018 VAPA_1c18200 32e51ee170cf4b15d3a0f266f3ed52c9 452 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 52 144 1.3E-4 T 12-10-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain VAPA_1c18200 32e51ee170cf4b15d3a0f266f3ed52c9 452 TIGRFAM TIGR03247 glucar-dehydr: glucarate dehydratase 14 452 1.1E-261 T 12-10-2018 IPR017653 Glucarate dehydratase GO:0000287|GO:0008872|GO:0019394 KEGG: 00053+4.2.1.40|MetaCyc: PWY-6499 VAPA_1c18200 32e51ee170cf4b15d3a0f266f3ed52c9 452 Pfam PF13378 Enolase C-terminal domain-like 195 412 1.8E-36 T 12-10-2018 IPR029065 Enolase C-terminal domain-like VAPA_1c18200 32e51ee170cf4b15d3a0f266f3ed52c9 452 SUPERFAMILY SSF51604 146 420 4.88E-82 T 12-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily VAPA_1c18200 32e51ee170cf4b15d3a0f266f3ed52c9 452 SMART SM00922 192 292 8.5E-16 T 12-10-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal VAPA_1c18200 32e51ee170cf4b15d3a0f266f3ed52c9 452 Gene3D G3DSA:3.30.390.10 17 420 1.2E-174 T 12-10-2018 IPR029017 Enolase-like, N-terminal VAPA_1c38680 0aaa632ebee7275d321a1c7ac10e6df6 2625 SUPERFAMILY SSF52777 1573 1740 1.93E-45 T 12-10-2018 VAPA_1c38680 0aaa632ebee7275d321a1c7ac10e6df6 2625 Gene3D G3DSA:3.30.559.30 1742 1992 4.9E-129 T 12-10-2018 VAPA_1c38680 0aaa632ebee7275d321a1c7ac10e6df6 2625 Gene3D G3DSA:3.30.300.30 2414 2516 6.2E-37 T 12-10-2018 VAPA_1c38680 0aaa632ebee7275d321a1c7ac10e6df6 2625 SUPERFAMILY SSF52777 1101 1278 3.56E-39 T 12-10-2018 VAPA_1c38680 0aaa632ebee7275d321a1c7ac10e6df6 2625 Gene3D G3DSA:3.30.559.10 53 427 1.1E-140 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 VAPA_1c38680 0aaa632ebee7275d321a1c7ac10e6df6 2625 Pfam PF13193 AMP-binding enzyme C-terminal domain 2427 2501 1.1E-13 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain VAPA_1c38680 0aaa632ebee7275d321a1c7ac10e6df6 2625 Pfam PF13193 AMP-binding enzyme C-terminal domain 926 1000 8.8E-14 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain VAPA_1c38680 0aaa632ebee7275d321a1c7ac10e6df6 2625 Gene3D G3DSA:3.30.300.30 912 1013 1.7E-34 T 12-10-2018 VAPA_1c38680 0aaa632ebee7275d321a1c7ac10e6df6 2625 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2550 2565 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site VAPA_1c38680 0aaa632ebee7275d321a1c7ac10e6df6 2625 SMART SM00823 Phosphopantetheine attachment site 2526 2595 1.6E-5 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 VAPA_1c38680 0aaa632ebee7275d321a1c7ac10e6df6 2625 SMART SM00823 Phosphopantetheine attachment site 1025 1093 0.023 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 VAPA_1c38680 0aaa632ebee7275d321a1c7ac10e6df6 2625 SUPERFAMILY SSF47336 2518 2591 4.19E-21 T 12-10-2018 IPR036736 ACP-like superfamily VAPA_1c38680 0aaa632ebee7275d321a1c7ac10e6df6 2625 SUPERFAMILY SSF52777 1743 1986 4.0E-53 T 12-10-2018 VAPA_1c38680 0aaa632ebee7275d321a1c7ac10e6df6 2625 Pfam PF00501 AMP-binding enzyme 2017 2419 1.1E-101 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 VAPA_1c38680 0aaa632ebee7275d321a1c7ac10e6df6 2625 Pfam PF00501 AMP-binding enzyme 519 918 1.2E-88 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 VAPA_1c38680 0aaa632ebee7275d321a1c7ac10e6df6 2625 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 2038 2443 4.4E-136 T 12-10-2018 IPR010071 Amino acid adenylation domain VAPA_1c38680 0aaa632ebee7275d321a1c7ac10e6df6 2625 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 539 942 7.3E-126 T 12-10-2018 IPR010071 Amino acid adenylation domain VAPA_1c38680 0aaa632ebee7275d321a1c7ac10e6df6 2625 Gene3D G3DSA:3.30.559.30 1275 1539 5.3E-78 T 12-10-2018 VAPA_1c38680 0aaa632ebee7275d321a1c7ac10e6df6 2625 ProSitePatterns PS00455 Putative AMP-binding domain signature. 659 670 - T 12-10-2018 IPR020845 AMP-binding, conserved site VAPA_1c38680 0aaa632ebee7275d321a1c7ac10e6df6 2625 Gene3D G3DSA:1.10.1200.10 2517 2595 7.9E-28 T 12-10-2018 IPR036736 ACP-like superfamily VAPA_1c38680 0aaa632ebee7275d321a1c7ac10e6df6 2625 SUPERFAMILY SSF56801 2011 2539 2.09E-162 T 12-10-2018 VAPA_1c38680 0aaa632ebee7275d321a1c7ac10e6df6 2625 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1049 1064 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site VAPA_1c38680 0aaa632ebee7275d321a1c7ac10e6df6 2625 Gene3D G3DSA:1.10.1200.10 1014 1093 4.8E-23 T 12-10-2018 IPR036736 ACP-like superfamily VAPA_1c38680 0aaa632ebee7275d321a1c7ac10e6df6 2625 SUPERFAMILY SSF56801 478 1038 7.46E-156 T 12-10-2018 VAPA_1c38680 0aaa632ebee7275d321a1c7ac10e6df6 2625 SUPERFAMILY SSF52777 238 490 1.78E-57 T 12-10-2018 VAPA_1c38680 0aaa632ebee7275d321a1c7ac10e6df6 2625 SUPERFAMILY SSF52777 1289 1537 9.89E-42 T 12-10-2018 VAPA_1c38680 0aaa632ebee7275d321a1c7ac10e6df6 2625 Gene3D G3DSA:3.30.559.30 236 482 1.1E-140 T 12-10-2018 VAPA_1c38680 0aaa632ebee7275d321a1c7ac10e6df6 2625 Gene3D G3DSA:3.40.50.12780 2003 2413 5.1E-145 T 12-10-2018 VAPA_1c38680 0aaa632ebee7275d321a1c7ac10e6df6 2625 TIGRFAM TIGR01720 NRPS-para261: non-ribosomal peptide synthase domain TIGR01720 1407 1559 5.0E-40 T 12-10-2018 IPR010060 Non-ribosomal peptide synthase VAPA_1c38680 0aaa632ebee7275d321a1c7ac10e6df6 2625 Gene3D G3DSA:3.30.559.10 1094 1273 8.6E-51 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 VAPA_1c38680 0aaa632ebee7275d321a1c7ac10e6df6 2625 Gene3D G3DSA:3.40.50.12780 509 910 1.9E-132 T 12-10-2018 VAPA_1c38680 0aaa632ebee7275d321a1c7ac10e6df6 2625 ProSitePatterns PS00455 Putative AMP-binding domain signature. 2157 2168 - T 12-10-2018 IPR020845 AMP-binding, conserved site VAPA_1c38680 0aaa632ebee7275d321a1c7ac10e6df6 2625 Pfam PF00550 Phosphopantetheine attachment site 2528 2591 1.8E-13 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain VAPA_1c38680 0aaa632ebee7275d321a1c7ac10e6df6 2625 Pfam PF00550 Phosphopantetheine attachment site 1027 1087 1.8E-10 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain VAPA_1c38680 0aaa632ebee7275d321a1c7ac10e6df6 2625 Pfam PF00668 Condensation domain 49 498 2.6E-104 T 12-10-2018 IPR001242 Condensation domain VAPA_1c38680 0aaa632ebee7275d321a1c7ac10e6df6 2625 Pfam PF00668 Condensation domain 1569 1992 1.4E-80 T 12-10-2018 IPR001242 Condensation domain VAPA_1c38680 0aaa632ebee7275d321a1c7ac10e6df6 2625 Pfam PF00668 Condensation domain 1103 1538 1.4E-74 T 12-10-2018 IPR001242 Condensation domain VAPA_1c38680 0aaa632ebee7275d321a1c7ac10e6df6 2625 SUPERFAMILY SSF52777 55 232 1.05E-48 T 12-10-2018 VAPA_1c38680 0aaa632ebee7275d321a1c7ac10e6df6 2625 SUPERFAMILY SSF47336 1018 1087 1.57E-16 T 12-10-2018 IPR036736 ACP-like superfamily VAPA_1c38680 0aaa632ebee7275d321a1c7ac10e6df6 2625 Gene3D G3DSA:3.30.559.10 1573 1932 4.9E-129 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 VAPA_1c03050 a29477fdadf1dc7ad51883d2ab4eba6e 462 PRINTS PR01874 DNA repair protein radA signature 215 243 9.9E-94 T 12-10-2018 VAPA_1c03050 a29477fdadf1dc7ad51883d2ab4eba6e 462 PRINTS PR01874 DNA repair protein radA signature 250 276 9.9E-94 T 12-10-2018 VAPA_1c03050 a29477fdadf1dc7ad51883d2ab4eba6e 462 PRINTS PR01874 DNA repair protein radA signature 323 346 9.9E-94 T 12-10-2018 VAPA_1c03050 a29477fdadf1dc7ad51883d2ab4eba6e 462 PRINTS PR01874 DNA repair protein radA signature 84 112 9.9E-94 T 12-10-2018 VAPA_1c03050 a29477fdadf1dc7ad51883d2ab4eba6e 462 PRINTS PR01874 DNA repair protein radA signature 126 143 9.9E-94 T 12-10-2018 VAPA_1c03050 a29477fdadf1dc7ad51883d2ab4eba6e 462 PRINTS PR01874 DNA repair protein radA signature 176 200 9.9E-94 T 12-10-2018 VAPA_1c03050 a29477fdadf1dc7ad51883d2ab4eba6e 462 PRINTS PR01874 DNA repair protein radA signature 10 34 9.9E-94 T 12-10-2018 VAPA_1c03050 a29477fdadf1dc7ad51883d2ab4eba6e 462 Gene3D G3DSA:3.30.230.10 335 462 7.7E-17 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup VAPA_1c03050 a29477fdadf1dc7ad51883d2ab4eba6e 462 Gene3D G3DSA:3.40.50.300 68 285 1.0E-40 T 12-10-2018 VAPA_1c03050 a29477fdadf1dc7ad51883d2ab4eba6e 462 Hamap MF_01498 DNA repair protein RadA [radA]. 21 459 43.746 T 12-10-2018 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 VAPA_1c03050 a29477fdadf1dc7ad51883d2ab4eba6e 462 SMART SM00382 92 246 4.9E-7 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c03050 a29477fdadf1dc7ad51883d2ab4eba6e 462 SUPERFAMILY SSF52540 71 295 1.49E-50 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c03050 a29477fdadf1dc7ad51883d2ab4eba6e 462 Pfam PF13481 AAA domain 65 224 1.8E-14 T 12-10-2018 VAPA_1c03050 a29477fdadf1dc7ad51883d2ab4eba6e 462 SUPERFAMILY SSF54211 257 459 1.14E-39 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold VAPA_1c03050 a29477fdadf1dc7ad51883d2ab4eba6e 462 TIGRFAM TIGR00416 sms: DNA repair protein RadA 1 449 2.3E-187 T 12-10-2018 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 VAPA_2c10790 20b8b05e9335438353ed12c316f6a1f2 322 Gene3D G3DSA:3.40.190.10 124 247 5.9E-111 T 12-10-2018 VAPA_2c10790 20b8b05e9335438353ed12c316f6a1f2 322 SUPERFAMILY SSF53850 108 285 5.37E-17 T 12-10-2018 VAPA_2c10790 20b8b05e9335438353ed12c316f6a1f2 322 PIRSF PIRSF017082 1 321 1.8E-77 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_2c10790 20b8b05e9335438353ed12c316f6a1f2 322 Gene3D G3DSA:3.40.190.150 26 312 5.9E-111 T 12-10-2018 VAPA_2c10790 20b8b05e9335438353ed12c316f6a1f2 322 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 46 317 2.1E-86 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c26810 ade07a5b7651ce0f48a93ebca8d9596f 245 SUPERFAMILY SSF46785 22 91 1.36E-20 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c26810 ade07a5b7651ce0f48a93ebca8d9596f 245 Pfam PF07729 FCD domain 109 235 5.4E-23 T 12-10-2018 IPR011711 GntR, C-terminal VAPA_1c26810 ade07a5b7651ce0f48a93ebca8d9596f 245 Gene3D G3DSA:1.10.10.10 24 96 2.0E-20 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c26810 ade07a5b7651ce0f48a93ebca8d9596f 245 SUPERFAMILY SSF48008 107 240 6.02E-28 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal VAPA_1c26810 ade07a5b7651ce0f48a93ebca8d9596f 245 Pfam PF00392 Bacterial regulatory proteins, gntR family 24 87 5.8E-20 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_1c26810 ade07a5b7651ce0f48a93ebca8d9596f 245 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 47 61 2.3E-10 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_1c26810 ade07a5b7651ce0f48a93ebca8d9596f 245 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 61 77 2.3E-10 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_1c26810 ade07a5b7651ce0f48a93ebca8d9596f 245 SMART SM00345 28 87 3.4E-20 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_1c26810 ade07a5b7651ce0f48a93ebca8d9596f 245 Gene3D G3DSA:1.20.120.530 99 241 2.1E-28 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal VAPA_1c26810 ade07a5b7651ce0f48a93ebca8d9596f 245 SMART SM00895 109 235 6.1E-21 T 12-10-2018 IPR011711 GntR, C-terminal VAPA_1c12770 162b66236924af49b32b335c959b2344 345 ProSitePatterns PS00211 ABC transporters family signature. 166 180 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_1c12770 162b66236924af49b32b335c959b2344 345 Gene3D G3DSA:3.40.50.300 9 343 2.2E-92 T 12-10-2018 VAPA_1c12770 162b66236924af49b32b335c959b2344 345 SUPERFAMILY SSF52540 10 264 8.21E-62 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c12770 162b66236924af49b32b335c959b2344 345 Pfam PF00005 ABC transporter 30 193 3.2E-25 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c12770 162b66236924af49b32b335c959b2344 345 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 243 333 7.9E-20 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 VAPA_1c12770 162b66236924af49b32b335c959b2344 345 SMART SM00382 38 243 4.8E-14 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c12770 162b66236924af49b32b335c959b2344 345 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 245 314 1.1E-12 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 VAPA_1c36930 029b8cb3d99470af6351571f01dc7a19 333 Gene3D G3DSA:3.40.190.10 134 257 3.1E-96 T 12-10-2018 VAPA_1c36930 029b8cb3d99470af6351571f01dc7a19 333 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 57 328 2.6E-71 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c36930 029b8cb3d99470af6351571f01dc7a19 333 PIRSF PIRSF017082 7 332 9.6E-60 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c36930 029b8cb3d99470af6351571f01dc7a19 333 Gene3D G3DSA:3.40.190.150 37 322 3.1E-96 T 12-10-2018 VAPA_1c36930 029b8cb3d99470af6351571f01dc7a19 333 SUPERFAMILY SSF53850 121 298 1.11E-7 T 12-10-2018 VAPA_1c13590 794e9fe624516de99f054302992ea1b0 324 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 46 320 1.7E-86 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c13590 794e9fe624516de99f054302992ea1b0 324 Gene3D G3DSA:3.40.190.150 27 314 5.9E-104 T 12-10-2018 VAPA_1c13590 794e9fe624516de99f054302992ea1b0 324 PIRSF PIRSF017082 1 323 8.3E-74 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c13590 794e9fe624516de99f054302992ea1b0 324 SUPERFAMILY SSF53850 108 284 1.81E-11 T 12-10-2018 VAPA_1c13590 794e9fe624516de99f054302992ea1b0 324 Gene3D G3DSA:3.40.190.10 123 249 5.9E-104 T 12-10-2018 VAPA_1c24280 cfa74bdb2f7854a9a90d791f7df9d7fe 424 Gene3D G3DSA:3.30.70.360 224 336 1.0E-126 T 12-10-2018 VAPA_1c24280 cfa74bdb2f7854a9a90d791f7df9d7fe 424 PIRSF PIRSF001235 13 422 1.3E-120 T 12-10-2018 IPR010158 Amidase, carbamoylase-type GO:0016813 VAPA_1c24280 cfa74bdb2f7854a9a90d791f7df9d7fe 424 Pfam PF01546 Peptidase family M20/M25/M40 90 414 2.6E-34 T 12-10-2018 IPR002933 Peptidase M20 GO:0016787 VAPA_1c24280 cfa74bdb2f7854a9a90d791f7df9d7fe 424 Pfam PF07687 Peptidase dimerisation domain 221 321 1.1E-4 T 12-10-2018 IPR011650 Peptidase M20, dimerisation domain VAPA_1c24280 cfa74bdb2f7854a9a90d791f7df9d7fe 424 SUPERFAMILY SSF53187 11 418 6.0E-83 T 12-10-2018 VAPA_1c24280 cfa74bdb2f7854a9a90d791f7df9d7fe 424 TIGRFAM TIGR01879 hydantase: amidase, hydantoinase/carbamoylase family 18 415 8.2E-113 T 12-10-2018 IPR010158 Amidase, carbamoylase-type GO:0016813 VAPA_1c24280 cfa74bdb2f7854a9a90d791f7df9d7fe 424 Gene3D G3DSA:3.40.630.10 27 411 1.0E-126 T 12-10-2018 VAPA_1c24280 cfa74bdb2f7854a9a90d791f7df9d7fe 424 SUPERFAMILY SSF55031 224 327 1.79E-20 T 12-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain VAPA_2c04180 bb53308d5add9ca727aa9ee26ea60faa 211 Gene3D G3DSA:3.40.50.1820 4 206 3.1E-58 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_2c04180 bb53308d5add9ca727aa9ee26ea60faa 211 Pfam PF00561 alpha/beta hydrolase fold 27 133 2.8E-8 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 VAPA_2c04180 bb53308d5add9ca727aa9ee26ea60faa 211 SUPERFAMILY SSF53474 13 206 3.6E-33 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_2c01740 ada2c88861d6efd738fb43d9139b9a28 623 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 206 612 3.6E-92 T 12-10-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit VAPA_2c01740 ada2c88861d6efd738fb43d9139b9a28 623 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 40 165 3.4E-27 T 12-10-2018 IPR007387 TRAP transporter, small membrane protein DctQ VAPA_2c01740 ada2c88861d6efd738fb43d9139b9a28 623 TIGRFAM TIGR00786 dctM: TRAP transporter, DctM subunit 213 618 1.5E-91 T 12-10-2018 IPR004681 TRAP transporter large membrane protein DctM GO:0016021 VAPA_1c16750 018a207190279124951e69da8b4a1ab9 262 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 43 57 2.3E-8 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_1c16750 018a207190279124951e69da8b4a1ab9 262 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 57 73 2.3E-8 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_1c16750 018a207190279124951e69da8b4a1ab9 262 SUPERFAMILY SSF46785 14 89 3.8E-16 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c16750 018a207190279124951e69da8b4a1ab9 262 Pfam PF00392 Bacterial regulatory proteins, gntR family 21 80 1.0E-15 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_1c16750 018a207190279124951e69da8b4a1ab9 262 SUPERFAMILY SSF48008 109 244 9.68E-21 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal VAPA_1c16750 018a207190279124951e69da8b4a1ab9 262 Pfam PF07729 FCD domain 111 235 3.0E-23 T 12-10-2018 IPR011711 GntR, C-terminal VAPA_1c16750 018a207190279124951e69da8b4a1ab9 262 Gene3D G3DSA:1.20.120.530 107 248 2.2E-22 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal VAPA_1c16750 018a207190279124951e69da8b4a1ab9 262 SMART SM00895 110 237 1.9E-17 T 12-10-2018 IPR011711 GntR, C-terminal VAPA_1c16750 018a207190279124951e69da8b4a1ab9 262 SMART SM00345 24 85 3.6E-13 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_1c16750 018a207190279124951e69da8b4a1ab9 262 Gene3D G3DSA:1.10.10.10 14 89 2.4E-17 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c23270 9d10d251b482bbef288c75903b47becb 364 Gene3D G3DSA:2.60.120.380 257 363 1.6E-9 T 12-10-2018 VAPA_1c23270 9d10d251b482bbef288c75903b47becb 364 Pfam PF01400 Astacin (Peptidase family M12A) 97 254 2.2E-6 T 12-10-2018 IPR001506 Peptidase M12A GO:0004222|GO:0006508 VAPA_1c23270 9d10d251b482bbef288c75903b47becb 364 SMART SM00235 57 219 2.7E-5 T 12-10-2018 IPR006026 Peptidase, metallopeptidase GO:0006508|GO:0008237|GO:0008270 VAPA_1c23270 9d10d251b482bbef288c75903b47becb 364 SUPERFAMILY SSF55486 57 255 1.47E-27 T 12-10-2018 VAPA_1c23270 9d10d251b482bbef288c75903b47becb 364 Gene3D G3DSA:3.40.390.10 52 255 3.0E-28 T 12-10-2018 IPR024079 Metallopeptidase, catalytic domain superfamily GO:0008237 VAPA_1c23270 9d10d251b482bbef288c75903b47becb 364 SUPERFAMILY SSF89260 275 360 5.89E-5 T 12-10-2018 VAPA_1c24440 843d4d2a88d8093b73cf830e7ffe5e26 559 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 230 541 5.6E-32 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 VAPA_1c24440 843d4d2a88d8093b73cf830e7ffe5e26 559 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 231 253 3.0E-33 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 VAPA_1c24440 843d4d2a88d8093b73cf830e7ffe5e26 559 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 374 398 3.0E-33 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 VAPA_1c24440 843d4d2a88d8093b73cf830e7ffe5e26 559 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 515 533 3.0E-33 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 VAPA_1c24440 843d4d2a88d8093b73cf830e7ffe5e26 559 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 428 444 3.0E-33 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 VAPA_1c24440 843d4d2a88d8093b73cf830e7ffe5e26 559 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 264 279 3.0E-33 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 VAPA_1c24440 843d4d2a88d8093b73cf830e7ffe5e26 559 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 336 344 3.0E-33 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 VAPA_1c24440 843d4d2a88d8093b73cf830e7ffe5e26 559 Gene3D G3DSA:3.50.50.60 232 546 2.0E-87 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c24440 843d4d2a88d8093b73cf830e7ffe5e26 559 Gene3D G3DSA:3.50.50.60 352 479 2.0E-87 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c24440 843d4d2a88d8093b73cf830e7ffe5e26 559 Gene3D G3DSA:2.60.120.10 12 144 2.2E-16 T 12-10-2018 IPR014710 RmlC-like jelly roll fold VAPA_1c24440 843d4d2a88d8093b73cf830e7ffe5e26 559 SMART SM00100 16 134 8.3E-7 T 12-10-2018 IPR000595 Cyclic nucleotide-binding domain VAPA_1c24440 843d4d2a88d8093b73cf830e7ffe5e26 559 SUPERFAMILY SSF51206 16 141 3.14E-21 T 12-10-2018 IPR018490 Cyclic nucleotide-binding-like VAPA_1c24440 843d4d2a88d8093b73cf830e7ffe5e26 559 SUPERFAMILY SSF51905 225 552 9.72E-44 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c24440 843d4d2a88d8093b73cf830e7ffe5e26 559 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 232 251 2.8E-23 T 12-10-2018 VAPA_1c24440 843d4d2a88d8093b73cf830e7ffe5e26 559 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 378 396 2.8E-23 T 12-10-2018 VAPA_1c24440 843d4d2a88d8093b73cf830e7ffe5e26 559 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 466 482 2.8E-23 T 12-10-2018 VAPA_1c24440 843d4d2a88d8093b73cf830e7ffe5e26 559 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 335 353 2.8E-23 T 12-10-2018 VAPA_1c24440 843d4d2a88d8093b73cf830e7ffe5e26 559 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 505 527 2.8E-23 T 12-10-2018 VAPA_1c24440 843d4d2a88d8093b73cf830e7ffe5e26 559 Pfam PF00027 Cyclic nucleotide-binding domain 35 119 1.3E-11 T 12-10-2018 IPR000595 Cyclic nucleotide-binding domain VAPA_1c25120 1de5f35a190ba37105b88461bd89a163 567 SUPERFAMILY SSF51569 20 328 8.79E-94 T 12-10-2018 VAPA_1c25120 1de5f35a190ba37105b88461bd89a163 567 TIGRFAM TIGR00970 leuA_yeast: 2-isopropylmalate synthase 5 552 1.4E-229 T 12-10-2018 IPR005668 2-isopropylmalate synthase GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 VAPA_1c25120 1de5f35a190ba37105b88461bd89a163 567 Pfam PF00682 HMGL-like 31 311 7.3E-70 T 12-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 VAPA_1c25120 1de5f35a190ba37105b88461bd89a163 567 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 38 54 - T 12-10-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 VAPA_1c25120 1de5f35a190ba37105b88461bd89a163 567 ProSitePatterns PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2. 241 254 - T 12-10-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 VAPA_1c25120 1de5f35a190ba37105b88461bd89a163 567 Gene3D G3DSA:3.30.160.270 375 552 2.3E-55 T 12-10-2018 VAPA_1c25120 1de5f35a190ba37105b88461bd89a163 567 SUPERFAMILY SSF89000 386 434 5.49E-13 T 12-10-2018 VAPA_1c25120 1de5f35a190ba37105b88461bd89a163 567 SMART SM00917 420 553 6.1E-34 T 12-10-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 VAPA_1c25120 1de5f35a190ba37105b88461bd89a163 567 Hamap MF_00572 2-isopropylmalate synthase [leuA]. 6 554 52.28 T 12-10-2018 IPR005668 2-isopropylmalate synthase GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 VAPA_1c25120 1de5f35a190ba37105b88461bd89a163 567 Gene3D G3DSA:3.20.20.70 9 374 8.5E-150 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 VAPA_1c25120 1de5f35a190ba37105b88461bd89a163 567 SUPERFAMILY SSF110921 453 551 5.1E-31 T 12-10-2018 IPR036230 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain superfamily KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 VAPA_1c25120 1de5f35a190ba37105b88461bd89a163 567 Pfam PF08502 LeuA allosteric (dimerisation) domain 420 551 3.0E-30 T 12-10-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 VAPA_1c43500 fb50581e8e546dfa0781b95d5280b66c 226 PRINTS PR01008 Flagellar L-ring protein signature 69 81 6.2E-29 T 12-10-2018 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 VAPA_1c43500 fb50581e8e546dfa0781b95d5280b66c 226 PRINTS PR01008 Flagellar L-ring protein signature 140 155 6.2E-29 T 12-10-2018 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 VAPA_1c43500 fb50581e8e546dfa0781b95d5280b66c 226 PRINTS PR01008 Flagellar L-ring protein signature 203 217 6.2E-29 T 12-10-2018 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 VAPA_1c43500 fb50581e8e546dfa0781b95d5280b66c 226 PRINTS PR01008 Flagellar L-ring protein signature 166 182 6.2E-29 T 12-10-2018 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 VAPA_1c43500 fb50581e8e546dfa0781b95d5280b66c 226 PRINTS PR01008 Flagellar L-ring protein signature 187 201 6.2E-29 T 12-10-2018 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 VAPA_1c43500 fb50581e8e546dfa0781b95d5280b66c 226 Hamap MF_00415 Flagellar L-ring protein [flgH]. 5 224 24.823 T 12-10-2018 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 VAPA_1c43500 fb50581e8e546dfa0781b95d5280b66c 226 Pfam PF02107 Flagellar L-ring protein 46 225 2.1E-56 T 12-10-2018 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 VAPA_1c12680 0ca1260ef14fba044077c1990add78c1 573 TIGRFAM TIGR00644 recJ: single-stranded-DNA-specific exonuclease RecJ 22 568 1.5E-128 T 12-10-2018 IPR004610 Bacterial RecJ exonuclease GO:0006281|GO:0006310|GO:0008409 VAPA_1c12680 0ca1260ef14fba044077c1990add78c1 573 Gene3D G3DSA:3.10.310.30 338 463 5.2E-30 T 12-10-2018 VAPA_1c12680 0ca1260ef14fba044077c1990add78c1 573 SUPERFAMILY SSF64182 47 469 3.53E-108 T 12-10-2018 IPR038763 DHH phosphoesterase superfamily VAPA_1c12680 0ca1260ef14fba044077c1990add78c1 573 Pfam PF01368 DHH family 75 182 1.7E-8 T 12-10-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 VAPA_1c12680 0ca1260ef14fba044077c1990add78c1 573 Pfam PF02272 DHHA1 domain 320 457 1.1E-17 T 12-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 VAPA_1c12680 0ca1260ef14fba044077c1990add78c1 573 Gene3D G3DSA:3.90.1640.30 49 323 5.2E-79 T 12-10-2018 VAPA_1c02340 61fff17c61a06f6cc2a2f9405f06151e 383 TIGRFAM TIGR03347 VI_chp_1: type VI secretion protein, VC_A0111 family 47 346 1.0E-99 T 12-10-2018 IPR010732 Type VI secretion, TssG-like VAPA_1c02340 61fff17c61a06f6cc2a2f9405f06151e 383 Pfam PF06996 Type VI secretion, TssG 47 346 1.7E-102 T 12-10-2018 IPR010732 Type VI secretion, TssG-like VAPA_1c14100 aab6f9ed9c29ed58d6634a00d41b61ef 395 Pfam PF07730 Histidine kinase 182 259 4.0E-12 T 12-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 VAPA_1c14100 aab6f9ed9c29ed58d6634a00d41b61ef 395 SMART SM00091 17 84 4.1E-7 T 12-10-2018 IPR000014 PAS domain VAPA_1c14100 aab6f9ed9c29ed58d6634a00d41b61ef 395 Gene3D G3DSA:3.30.565.10 258 392 2.5E-27 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_1c14100 aab6f9ed9c29ed58d6634a00d41b61ef 395 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 20 143 1.6E-16 T 12-10-2018 IPR000014 PAS domain VAPA_1c14100 aab6f9ed9c29ed58d6634a00d41b61ef 395 SMART SM00387 299 393 1.1E-5 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase VAPA_1c14100 aab6f9ed9c29ed58d6634a00d41b61ef 395 Gene3D G3DSA:3.30.450.20 16 149 3.2E-23 T 12-10-2018 VAPA_1c14100 aab6f9ed9c29ed58d6634a00d41b61ef 395 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 303 391 6.6E-9 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase VAPA_1c14100 aab6f9ed9c29ed58d6634a00d41b61ef 395 SUPERFAMILY SSF55874 254 391 1.26E-17 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_1c14100 aab6f9ed9c29ed58d6634a00d41b61ef 395 Pfam PF00989 PAS fold 22 133 4.7E-12 T 12-10-2018 IPR013767 PAS fold GO:0006355 VAPA_1c14100 aab6f9ed9c29ed58d6634a00d41b61ef 395 PRINTS PR00344 Bacterial sensor protein C-terminal signature 377 390 7.3E-5 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c14100 aab6f9ed9c29ed58d6634a00d41b61ef 395 PRINTS PR00344 Bacterial sensor protein C-terminal signature 335 349 7.3E-5 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c14100 aab6f9ed9c29ed58d6634a00d41b61ef 395 SUPERFAMILY SSF55785 28 144 2.97E-20 T 12-10-2018 IPR035965 PAS domain superfamily VAPA_1c06100 4e8977005357dc080fca0c62f37e7e52 350 Pfam PF13599 Pentapeptide repeats (9 copies) 86 143 1.9E-6 T 12-10-2018 IPR001646 Pentapeptide repeat VAPA_1c06100 4e8977005357dc080fca0c62f37e7e52 350 Pfam PF13599 Pentapeptide repeats (9 copies) 264 327 7.5E-11 T 12-10-2018 IPR001646 Pentapeptide repeat VAPA_1c06100 4e8977005357dc080fca0c62f37e7e52 350 SUPERFAMILY SSF141571 156 324 1.77E-44 T 12-10-2018 VAPA_1c06100 4e8977005357dc080fca0c62f37e7e52 350 Gene3D G3DSA:2.160.20.100 5 175 3.9E-34 T 12-10-2018 VAPA_1c06100 4e8977005357dc080fca0c62f37e7e52 350 Gene3D G3DSA:2.160.20.100 176 336 4.9E-41 T 12-10-2018 VAPA_1c06100 4e8977005357dc080fca0c62f37e7e52 350 Pfam PF00805 Pentapeptide repeats (8 copies) 40 78 7.3E-11 T 12-10-2018 IPR001646 Pentapeptide repeat VAPA_1c06100 4e8977005357dc080fca0c62f37e7e52 350 Pfam PF00805 Pentapeptide repeats (8 copies) 191 227 1.3E-11 T 12-10-2018 IPR001646 Pentapeptide repeat VAPA_1c06100 4e8977005357dc080fca0c62f37e7e52 350 SUPERFAMILY SSF141571 12 172 3.66E-34 T 12-10-2018 VAPA_1c28880 33dd02b31fd3d3f76b5619b920693c3a 531 Gene3D G3DSA:3.40.50.300 260 517 1.8E-30 T 12-10-2018 VAPA_1c28880 33dd02b31fd3d3f76b5619b920693c3a 531 Pfam PF00005 ABC transporter 23 171 7.3E-30 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c28880 33dd02b31fd3d3f76b5619b920693c3a 531 Gene3D G3DSA:3.40.50.300 2 248 3.6E-58 T 12-10-2018 VAPA_1c28880 33dd02b31fd3d3f76b5619b920693c3a 531 ProSitePatterns PS00211 ABC transporters family signature. 143 157 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_1c28880 33dd02b31fd3d3f76b5619b920693c3a 531 SMART SM00382 31 218 1.1E-12 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c28880 33dd02b31fd3d3f76b5619b920693c3a 531 ProSitePatterns PS00211 ABC transporters family signature. 406 420 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_1c28880 33dd02b31fd3d3f76b5619b920693c3a 531 Pfam PF00005 ABC transporter 277 421 2.1E-10 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c28880 33dd02b31fd3d3f76b5619b920693c3a 531 SUPERFAMILY SSF52540 5 229 6.25E-58 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c28880 33dd02b31fd3d3f76b5619b920693c3a 531 SUPERFAMILY SSF52540 255 499 1.31E-30 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c33900 9a040ce4629122eb07163fc567c9bd03 192 TIGRFAM TIGR01926 peroxid_rel: uncharacterized peroxidase-related enzyme 6 180 1.8E-69 T 12-10-2018 IPR010195 Uncharacterised peroxidase-related VAPA_1c33900 9a040ce4629122eb07163fc567c9bd03 192 Pfam PF02627 Carboxymuconolactone decarboxylase family 46 122 9.8E-12 T 12-10-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 VAPA_1c33900 9a040ce4629122eb07163fc567c9bd03 192 Gene3D G3DSA:1.20.5.810 9 61 5.9E-25 T 12-10-2018 VAPA_1c33900 9a040ce4629122eb07163fc567c9bd03 192 Gene3D G3DSA:1.20.1290.10 63 186 2.6E-41 T 12-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 VAPA_1c33900 9a040ce4629122eb07163fc567c9bd03 192 SUPERFAMILY SSF69118 4 187 6.41E-55 T 12-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 VAPA_1c33900 9a040ce4629122eb07163fc567c9bd03 192 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 61 93 1.9E-9 T 12-10-2018 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 VAPA_1c28560 78837a8d18323c04284e6337ed88c584 508 SUPERFAMILY SSF50249 38 135 1.4E-15 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold VAPA_1c28560 78837a8d18323c04284e6337ed88c584 508 Pfam PF10150 Ribonuclease E/G family 131 412 1.3E-95 T 12-10-2018 IPR019307 RNA-binding protein AU-1/Ribonuclease E/G GO:0003723 VAPA_1c28560 78837a8d18323c04284e6337ed88c584 508 TIGRFAM TIGR00757 RNaseEG: ribonuclease, Rne/Rng family 12 445 8.3E-144 T 12-10-2018 IPR004659 Ribonuclease E/G GO:0003723|GO:0004540|GO:0006396 VAPA_1c28560 78837a8d18323c04284e6337ed88c584 508 SMART SM00316 36 129 3.0E-7 T 12-10-2018 IPR022967 RNA-binding domain, S1 VAPA_1c28560 78837a8d18323c04284e6337ed88c584 508 Gene3D G3DSA:2.40.50.140 30 135 7.7E-28 T 12-10-2018 VAPA_1c30290 46dbc7d925e69fa47cc765375b523c18 320 SUPERFAMILY SSF53850 90 297 3.57E-46 T 12-10-2018 VAPA_1c30290 46dbc7d925e69fa47cc765375b523c18 320 Gene3D G3DSA:3.40.190.10 163 264 1.2E-61 T 12-10-2018 VAPA_1c30290 46dbc7d925e69fa47cc765375b523c18 320 Gene3D G3DSA:3.40.190.10 91 290 1.2E-61 T 12-10-2018 VAPA_1c30290 46dbc7d925e69fa47cc765375b523c18 320 Pfam PF03466 LysR substrate binding domain 88 292 2.3E-42 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_1c30290 46dbc7d925e69fa47cc765375b523c18 320 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 63 7.5E-19 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c30290 46dbc7d925e69fa47cc765375b523c18 320 SUPERFAMILY SSF46785 3 112 6.06E-23 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c30290 46dbc7d925e69fa47cc765375b523c18 320 Gene3D G3DSA:1.10.10.10 3 89 5.6E-26 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c18970 59e2697ee3ac72bdc68eda414c525ab5 158 Gene3D G3DSA:1.20.1260.10 1 157 4.8E-69 T 12-10-2018 IPR012347 Ferritin-like VAPA_1c18970 59e2697ee3ac72bdc68eda414c525ab5 158 ProSitePatterns PS00549 Bacterioferritin signature. 1 19 - T 12-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 VAPA_1c18970 59e2697ee3ac72bdc68eda414c525ab5 158 PRINTS PR00601 Bacterioferritin signature 44 64 1.3E-65 T 12-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 VAPA_1c18970 59e2697ee3ac72bdc68eda414c525ab5 158 PRINTS PR00601 Bacterioferritin signature 86 106 1.3E-65 T 12-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 VAPA_1c18970 59e2697ee3ac72bdc68eda414c525ab5 158 PRINTS PR00601 Bacterioferritin signature 128 149 1.3E-65 T 12-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 VAPA_1c18970 59e2697ee3ac72bdc68eda414c525ab5 158 PRINTS PR00601 Bacterioferritin signature 107 127 1.3E-65 T 12-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 VAPA_1c18970 59e2697ee3ac72bdc68eda414c525ab5 158 PRINTS PR00601 Bacterioferritin signature 23 43 1.3E-65 T 12-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 VAPA_1c18970 59e2697ee3ac72bdc68eda414c525ab5 158 PRINTS PR00601 Bacterioferritin signature 65 85 1.3E-65 T 12-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 VAPA_1c18970 59e2697ee3ac72bdc68eda414c525ab5 158 PRINTS PR00601 Bacterioferritin signature 3 22 1.3E-65 T 12-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 VAPA_1c18970 59e2697ee3ac72bdc68eda414c525ab5 158 TIGRFAM TIGR00754 bfr: bacterioferritin 1 156 8.0E-74 T 12-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 VAPA_1c18970 59e2697ee3ac72bdc68eda414c525ab5 158 SUPERFAMILY SSF47240 1 155 1.67E-53 T 12-10-2018 IPR009078 Ferritin-like superfamily VAPA_1c18970 59e2697ee3ac72bdc68eda414c525ab5 158 Pfam PF00210 Ferritin-like domain 8 143 1.2E-39 T 12-10-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 VAPA_1c18970 59e2697ee3ac72bdc68eda414c525ab5 158 PIRSF PIRSF002560 1 157 4.5E-72 T 12-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 VAPA_1c05490 29ba378f7106ce269f4de9a6f24b7cb0 211 Gene3D G3DSA:2.40.128.110 41 209 1.5E-42 T 12-10-2018 IPR036761 Lipid/polyisoprenoid-binding, YceI-like superfamily VAPA_1c05490 29ba378f7106ce269f4de9a6f24b7cb0 211 SMART SM00867 43 207 1.0E-49 T 12-10-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like VAPA_1c05490 29ba378f7106ce269f4de9a6f24b7cb0 211 SUPERFAMILY SSF101874 42 207 6.02E-46 T 12-10-2018 IPR036761 Lipid/polyisoprenoid-binding, YceI-like superfamily VAPA_1c05490 29ba378f7106ce269f4de9a6f24b7cb0 211 Pfam PF04264 YceI-like domain 44 206 1.6E-32 T 12-10-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like VAPA_1c19140 cff4938630e8ab746737932bfa17f26d 126 Pfam PF04430 Protein of unknown function (DUF498/DUF598) 14 120 5.5E-30 T 12-10-2018 IPR007523 NDUFAF3/Mth938 domain-containing protein VAPA_1c19140 cff4938630e8ab746737932bfa17f26d 126 Gene3D G3DSA:3.40.1230.10 1 123 4.7E-32 T 12-10-2018 IPR036748 MTH938-like superfamily VAPA_1c19140 cff4938630e8ab746737932bfa17f26d 126 SUPERFAMILY SSF64076 6 121 5.36E-36 T 12-10-2018 IPR036748 MTH938-like superfamily VAPA_1c53290 95df4c984d6f8815becc82aac9030894 320 PRINTS PR00409 Phthalate dioxygenase reductase family signature 31 41 9.4E-39 T 12-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 VAPA_1c53290 95df4c984d6f8815becc82aac9030894 320 PRINTS PR00409 Phthalate dioxygenase reductase family signature 41 53 9.4E-39 T 12-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 VAPA_1c53290 95df4c984d6f8815becc82aac9030894 320 PRINTS PR00409 Phthalate dioxygenase reductase family signature 78 92 9.4E-39 T 12-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 VAPA_1c53290 95df4c984d6f8815becc82aac9030894 320 PRINTS PR00409 Phthalate dioxygenase reductase family signature 114 133 9.4E-39 T 12-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 VAPA_1c53290 95df4c984d6f8815becc82aac9030894 320 PRINTS PR00409 Phthalate dioxygenase reductase family signature 92 106 9.4E-39 T 12-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 VAPA_1c53290 95df4c984d6f8815becc82aac9030894 320 PRINTS PR00409 Phthalate dioxygenase reductase family signature 193 201 9.4E-39 T 12-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 VAPA_1c53290 95df4c984d6f8815becc82aac9030894 320 Gene3D G3DSA:2.40.30.10 2 103 7.0E-28 T 12-10-2018 VAPA_1c53290 95df4c984d6f8815becc82aac9030894 320 SUPERFAMILY SSF63380 5 102 1.51E-24 T 12-10-2018 IPR017938 Riboflavin synthase-like beta-barrel VAPA_1c53290 95df4c984d6f8815becc82aac9030894 320 SUPERFAMILY SSF52343 104 221 2.62E-29 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain VAPA_1c53290 95df4c984d6f8815becc82aac9030894 320 Gene3D G3DSA:3.10.20.30 226 320 8.1E-18 T 12-10-2018 IPR012675 Beta-grasp domain superfamily VAPA_1c53290 95df4c984d6f8815becc82aac9030894 320 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 271 279 - T 12-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 VAPA_1c53290 95df4c984d6f8815becc82aac9030894 320 Pfam PF00175 Oxidoreductase NAD-binding domain 115 207 8.4E-5 T 12-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 VAPA_1c53290 95df4c984d6f8815becc82aac9030894 320 Gene3D G3DSA:3.40.50.80 104 223 2.5E-30 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain VAPA_1c53290 95df4c984d6f8815becc82aac9030894 320 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 243 309 8.3E-11 T 12-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 VAPA_1c53290 95df4c984d6f8815becc82aac9030894 320 SUPERFAMILY SSF54292 213 317 3.28E-20 T 12-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 VAPA_1c33710 ce25a4b792ec0c815a5b52c8a95edef0 267 Pfam PF01144 Coenzyme A transferase 7 217 1.6E-78 T 12-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 VAPA_1c33710 ce25a4b792ec0c815a5b52c8a95edef0 267 SUPERFAMILY SSF100950 2 228 7.18E-89 T 12-10-2018 IPR037171 NagB/RpiA transferase-like VAPA_1c33710 ce25a4b792ec0c815a5b52c8a95edef0 267 SMART SM00882 5 217 1.8E-92 T 12-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 VAPA_1c33710 ce25a4b792ec0c815a5b52c8a95edef0 267 TIGRFAM TIGR02429 pcaI_scoA_fam: 3-oxoacid CoA-transferase, A subunit 1 217 6.9E-79 T 12-10-2018 IPR012792 3-oxoacid CoA-transferase, subunit A GO:0008410 Reactome: R-HSA-77108 VAPA_1c33710 ce25a4b792ec0c815a5b52c8a95edef0 267 Gene3D G3DSA:3.40.1080.10 1 227 4.0E-97 T 12-10-2018 VAPA_1c33710 ce25a4b792ec0c815a5b52c8a95edef0 267 ProSitePatterns PS01273 Coenzyme A transferases signature 1. 18 33 - T 12-10-2018 IPR004163 Coenzyme A transferase binding site GO:0008410 Reactome: R-HSA-77108 VAPA_2c04960 edac4c08dc3508507daae80fa88fb9be 469 Pfam PF02321 Outer membrane efflux protein 260 449 1.3E-24 T 12-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 VAPA_2c04960 edac4c08dc3508507daae80fa88fb9be 469 Pfam PF02321 Outer membrane efflux protein 34 237 6.3E-18 T 12-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 VAPA_2c04960 edac4c08dc3508507daae80fa88fb9be 469 SUPERFAMILY SSF56954 8 453 2.88E-69 T 12-10-2018 VAPA_2c04960 edac4c08dc3508507daae80fa88fb9be 469 Gene3D G3DSA:1.20.1600.10 31 467 2.1E-81 T 12-10-2018 VAPA_1c27960 0bbe4117856fc4ecfc70e6571ada91f7 82 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 3 42 8.3E-11 T 12-10-2018 VAPA_1c27960 0bbe4117856fc4ecfc70e6571ada91f7 82 Gene3D G3DSA:3.40.1620.10 1 39 2.7E-9 T 12-10-2018 VAPA_1c27960 0bbe4117856fc4ecfc70e6571ada91f7 82 SUPERFAMILY SSF143120 1 43 7.85E-12 T 12-10-2018 IPR036165 YefM-like superfamily VAPA_1c27960 0bbe4117856fc4ecfc70e6571ada91f7 82 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 1 50 2.3E-15 T 12-10-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM VAPA_1c54310 31a418026ac118a05424714d8aadad66 305 SUPERFAMILY SSF51569 4 291 1.36E-80 T 12-10-2018 VAPA_1c54310 31a418026ac118a05424714d8aadad66 305 Pfam PF00701 Dihydrodipicolinate synthetase family 7 292 9.5E-55 T 12-10-2018 IPR002220 DapA-like GO:0016829 VAPA_1c54310 31a418026ac118a05424714d8aadad66 305 Gene3D G3DSA:3.20.20.70 3 299 6.7E-80 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 VAPA_1c54310 31a418026ac118a05424714d8aadad66 305 PRINTS PR00146 Dihydrodipicolinate synthase signature 75 93 2.4E-13 T 12-10-2018 IPR002220 DapA-like GO:0016829 VAPA_1c54310 31a418026ac118a05424714d8aadad66 305 PRINTS PR00146 Dihydrodipicolinate synthase signature 132 149 2.4E-13 T 12-10-2018 IPR002220 DapA-like GO:0016829 VAPA_1c54310 31a418026ac118a05424714d8aadad66 305 PRINTS PR00146 Dihydrodipicolinate synthase signature 39 60 2.4E-13 T 12-10-2018 IPR002220 DapA-like GO:0016829 VAPA_1c54310 31a418026ac118a05424714d8aadad66 305 PIRSF PIRSF001365 2 302 1.3E-76 T 12-10-2018 IPR002220 DapA-like GO:0016829 VAPA_1c54310 31a418026ac118a05424714d8aadad66 305 SMART SM01130 5 293 4.9E-82 T 12-10-2018 IPR002220 DapA-like GO:0016829 VAPA_1c34520 f7b5e0b19a8b464feeb8073032fa2193 148 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 45 60 2.2E-7 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 VAPA_1c34520 f7b5e0b19a8b464feeb8073032fa2193 148 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 60 75 2.2E-7 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 VAPA_1c34520 f7b5e0b19a8b464feeb8073032fa2193 148 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 13 28 2.2E-7 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 VAPA_1c34520 f7b5e0b19a8b464feeb8073032fa2193 148 Pfam PF12840 Helix-turn-helix domain 10 69 7.1E-16 T 12-10-2018 VAPA_1c34520 f7b5e0b19a8b464feeb8073032fa2193 148 SMART SM00418 11 89 1.3E-12 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 VAPA_1c34520 f7b5e0b19a8b464feeb8073032fa2193 148 SUPERFAMILY SSF46785 5 113 3.78E-26 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c34520 f7b5e0b19a8b464feeb8073032fa2193 148 Gene3D G3DSA:1.10.10.10 2 112 4.9E-28 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c23670 920ef44afb0a3d8b092e6f35b2e6c825 426 Gene3D G3DSA:3.30.413.10 304 421 1.1E-37 T 12-10-2018 VAPA_1c23670 920ef44afb0a3d8b092e6f35b2e6c825 426 Hamap MF_00159 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (ferredoxin) [ispG]. 18 412 28.389 T 12-10-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 VAPA_1c23670 920ef44afb0a3d8b092e6f35b2e6c825 426 TIGRFAM TIGR00612 ispG_gcpE: 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 22 410 8.9E-115 T 12-10-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 VAPA_1c23670 920ef44afb0a3d8b092e6f35b2e6c825 426 SUPERFAMILY SSF56014 306 416 2.62E-7 T 12-10-2018 VAPA_1c23670 920ef44afb0a3d8b092e6f35b2e6c825 426 PIRSF PIRSF004640 11 420 1.3E-125 T 12-10-2018 IPR016425 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial GO:0005506|GO:0008299|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 VAPA_1c23670 920ef44afb0a3d8b092e6f35b2e6c825 426 Gene3D G3DSA:3.20.20.20 15 303 1.9E-92 T 12-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 VAPA_1c23670 920ef44afb0a3d8b092e6f35b2e6c825 426 Pfam PF04551 GcpE protein 30 410 1.9E-110 T 12-10-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 VAPA_1c15530 16eae4023a3fc1be212bcf1c0dec37a4 434 Pfam PF08281 Sigma-70, region 4 132 181 2.1E-8 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 VAPA_1c15530 16eae4023a3fc1be212bcf1c0dec37a4 434 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 25 183 3.5E-12 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 VAPA_1c15530 16eae4023a3fc1be212bcf1c0dec37a4 434 Gene3D G3DSA:1.10.10.10 133 185 6.0E-7 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c15530 16eae4023a3fc1be212bcf1c0dec37a4 434 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 42 73 - T 12-10-2018 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 VAPA_1c15530 16eae4023a3fc1be212bcf1c0dec37a4 434 Pfam PF04542 Sigma-70 region 2 27 84 2.3E-9 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 VAPA_1c15530 16eae4023a3fc1be212bcf1c0dec37a4 434 Gene3D G3DSA:1.10.1740.10 5 83 1.5E-7 T 12-10-2018 VAPA_1c15530 16eae4023a3fc1be212bcf1c0dec37a4 434 SUPERFAMILY SSF88659 121 183 1.46E-10 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like VAPA_1c15530 16eae4023a3fc1be212bcf1c0dec37a4 434 SUPERFAMILY SSF88946 16 83 7.46E-12 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 VAPA_1c52620 3c0c7e79d12fea7e67a625d2ac10124c 398 TIGRFAM TIGR00449 tgt_general: tRNA-guanine family transglycosylase 12 391 7.6E-142 T 12-10-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 VAPA_1c52620 3c0c7e79d12fea7e67a625d2ac10124c 398 Hamap MF_00168 Queuine tRNA-ribosyltransferase [tgt]. 10 393 53.303 T 12-10-2018 IPR004803 tRNA-guanine transglycosylase GO:0008479|GO:0101030 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 VAPA_1c52620 3c0c7e79d12fea7e67a625d2ac10124c 398 Pfam PF01702 Queuine tRNA-ribosyltransferase 138 390 1.5E-88 T 12-10-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 VAPA_1c52620 3c0c7e79d12fea7e67a625d2ac10124c 398 TIGRFAM TIGR00430 Q_tRNA_tgt: tRNA-guanine transglycosylase 20 392 1.0E-150 T 12-10-2018 IPR004803 tRNA-guanine transglycosylase GO:0008479|GO:0101030 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 VAPA_1c52620 3c0c7e79d12fea7e67a625d2ac10124c 398 SUPERFAMILY SSF51713 9 390 2.75E-148 T 12-10-2018 IPR036511 Queuine tRNA-ribosyltransferase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 VAPA_1c52620 3c0c7e79d12fea7e67a625d2ac10124c 398 Gene3D G3DSA:3.20.20.105 1 396 3.1E-158 T 12-10-2018 IPR036511 Queuine tRNA-ribosyltransferase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 VAPA_1c48720 1ade998bd6b15bad960eacf55b4c406f 104 TIGRFAM TIGR02118 TIGR02118: conserved hypothetical protein 1 102 6.2E-37 T 12-10-2018 IPR009799 EthD domain VAPA_1c48720 1ade998bd6b15bad960eacf55b4c406f 104 Gene3D G3DSA:3.30.70.100 2 100 4.2E-33 T 12-10-2018 VAPA_1c48720 1ade998bd6b15bad960eacf55b4c406f 104 Pfam PF07110 EthD domain 18 91 7.4E-9 T 12-10-2018 IPR009799 EthD domain VAPA_1c48720 1ade998bd6b15bad960eacf55b4c406f 104 SUPERFAMILY SSF54909 1 102 2.06E-22 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel VAPA_1c04370 44b553c50a641832699503f1fd8564f5 237 Gene3D G3DSA:3.40.50.720 1 237 1.6E-68 T 12-10-2018 VAPA_1c04370 44b553c50a641832699503f1fd8564f5 237 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 124 140 7.3E-31 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c04370 44b553c50a641832699503f1fd8564f5 237 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 171 188 7.3E-31 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c04370 44b553c50a641832699503f1fd8564f5 237 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 150 169 7.3E-31 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c04370 44b553c50a641832699503f1fd8564f5 237 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 197 217 7.3E-31 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c04370 44b553c50a641832699503f1fd8564f5 237 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 7.3E-31 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c04370 44b553c50a641832699503f1fd8564f5 237 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 77 88 7.3E-31 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c04370 44b553c50a641832699503f1fd8564f5 237 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 17 234 3.1E-48 T 12-10-2018 VAPA_1c04370 44b553c50a641832699503f1fd8564f5 237 SUPERFAMILY SSF51735 6 234 1.42E-62 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c04370 44b553c50a641832699503f1fd8564f5 237 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 77 88 4.5E-5 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c04370 44b553c50a641832699503f1fd8564f5 237 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 150 169 4.5E-5 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c04370 44b553c50a641832699503f1fd8564f5 237 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 130 138 4.5E-5 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c49190 a481fae6adf07bb3580e3d54f04a4ba4 292 SMART SM01091 204 286 1.3E-23 T 12-10-2018 IPR005170 Transporter-associated domain VAPA_1c49190 a481fae6adf07bb3580e3d54f04a4ba4 292 Gene3D G3DSA:3.30.465.10 203 286 4.9E-21 T 12-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 VAPA_1c49190 a481fae6adf07bb3580e3d54f04a4ba4 292 Pfam PF00571 CBS domain 82 125 1.4E-4 T 12-10-2018 IPR000644 CBS domain VAPA_1c49190 a481fae6adf07bb3580e3d54f04a4ba4 292 Pfam PF00571 CBS domain 139 187 1.4E-6 T 12-10-2018 IPR000644 CBS domain VAPA_1c49190 a481fae6adf07bb3580e3d54f04a4ba4 292 SUPERFAMILY SSF54631 59 197 2.78E-31 T 12-10-2018 VAPA_1c49190 a481fae6adf07bb3580e3d54f04a4ba4 292 Pfam PF03471 Transporter associated domain 207 284 4.7E-17 T 12-10-2018 IPR005170 Transporter-associated domain VAPA_1c49190 a481fae6adf07bb3580e3d54f04a4ba4 292 Gene3D G3DSA:3.10.580.10 50 201 3.1E-48 T 12-10-2018 VAPA_1c49190 a481fae6adf07bb3580e3d54f04a4ba4 292 SUPERFAMILY SSF56176 202 287 4.64E-18 T 12-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 VAPA_1c30120 b1c0d0ebfc2cc03857996eba855fd436 353 SUPERFAMILY SSF54909 74 124 2.61E-5 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel VAPA_1c30120 b1c0d0ebfc2cc03857996eba855fd436 353 Pfam PF13816 Haem-containing dehydratase 44 343 1.6E-94 T 12-10-2018 IPR025702 Haem-containing dehydratase KEGG: 00460+4.99.1.7|KEGG: 00643+4.99.1.7|MetaCyc: PWY-7824 VAPA_1c30120 b1c0d0ebfc2cc03857996eba855fd436 353 ProDom PD320837 DEHYDRATASE PHENYLACETALDOXIME ALDOXIME LYASE METAL-BINDING IRON HEME TRUNCATION DIRECT 4.2.1.- 1 347 4.0E-111 T 12-10-2018 IPR025702 Haem-containing dehydratase KEGG: 00460+4.99.1.7|KEGG: 00643+4.99.1.7|MetaCyc: PWY-7824 VAPA_1c34930 80415bfe2c614d11c3dddda421d2b5c8 255 Gene3D G3DSA:1.10.10.10 2 91 1.7E-7 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c34930 80415bfe2c614d11c3dddda421d2b5c8 255 ProSitePatterns PS00894 DeoR-type HTH domain signature. 6 40 - T 12-10-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 VAPA_1c34930 80415bfe2c614d11c3dddda421d2b5c8 255 Pfam PF00455 DeoR C terminal sensor domain 75 232 5.4E-52 T 12-10-2018 IPR014036 DeoR C-terminal sensor domain VAPA_1c34930 80415bfe2c614d11c3dddda421d2b5c8 255 SUPERFAMILY SSF100950 75 234 1.98E-26 T 12-10-2018 IPR037171 NagB/RpiA transferase-like VAPA_1c34930 80415bfe2c614d11c3dddda421d2b5c8 255 SMART SM00420 6 58 8.1E-14 T 12-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 VAPA_1c34930 80415bfe2c614d11c3dddda421d2b5c8 255 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 24 38 3.7E-9 T 12-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 VAPA_1c34930 80415bfe2c614d11c3dddda421d2b5c8 255 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 38 56 3.7E-9 T 12-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 VAPA_1c34930 80415bfe2c614d11c3dddda421d2b5c8 255 Pfam PF08220 DeoR-like helix-turn-helix domain 6 62 1.8E-16 T 12-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 VAPA_1c34930 80415bfe2c614d11c3dddda421d2b5c8 255 SUPERFAMILY SSF46785 4 62 3.17E-13 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c34930 80415bfe2c614d11c3dddda421d2b5c8 255 SMART SM00419 10 60 8.5E-4 T 12-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 VAPA_1c34930 80415bfe2c614d11c3dddda421d2b5c8 255 SMART SM01134 73 234 1.3E-70 T 12-10-2018 VAPA_2c01080 46a9d0c92d71fa4098f6a98309ceedaf 278 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 169 188 1.2E-31 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c01080 46a9d0c92d71fa4098f6a98309ceedaf 278 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 12 29 1.2E-31 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c01080 46a9d0c92d71fa4098f6a98309ceedaf 278 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 86 97 1.2E-31 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c01080 46a9d0c92d71fa4098f6a98309ceedaf 278 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 190 207 1.2E-31 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c01080 46a9d0c92d71fa4098f6a98309ceedaf 278 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 241 261 1.2E-31 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c01080 46a9d0c92d71fa4098f6a98309ceedaf 278 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 143 159 1.2E-31 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c01080 46a9d0c92d71fa4098f6a98309ceedaf 278 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 149 157 1.0E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c01080 46a9d0c92d71fa4098f6a98309ceedaf 278 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 169 188 1.0E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c01080 46a9d0c92d71fa4098f6a98309ceedaf 278 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 86 97 1.0E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c01080 46a9d0c92d71fa4098f6a98309ceedaf 278 SUPERFAMILY SSF51735 9 277 1.58E-69 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_2c01080 46a9d0c92d71fa4098f6a98309ceedaf 278 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 11 205 4.0E-4 T 12-10-2018 VAPA_2c01080 46a9d0c92d71fa4098f6a98309ceedaf 278 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 156 184 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 VAPA_2c01080 46a9d0c92d71fa4098f6a98309ceedaf 278 Gene3D G3DSA:3.40.50.720 6 278 3.7E-73 T 12-10-2018 VAPA_2c01080 46a9d0c92d71fa4098f6a98309ceedaf 278 Pfam PF00106 short chain dehydrogenase 11 209 9.2E-48 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c38260 47b7139f3097beb14f9be60c2ba30b36 227 Pfam PF00005 ABC transporter 25 168 1.3E-30 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c38260 47b7139f3097beb14f9be60c2ba30b36 227 SUPERFAMILY SSF52540 6 222 5.2E-70 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c38260 47b7139f3097beb14f9be60c2ba30b36 227 Gene3D G3DSA:3.40.50.300 3 226 1.1E-66 T 12-10-2018 VAPA_1c38260 47b7139f3097beb14f9be60c2ba30b36 227 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_1c38260 47b7139f3097beb14f9be60c2ba30b36 227 SMART SM00382 33 218 2.8E-16 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c18330 6622065fc99d66f0c92cff13c765d87e 257 SUPERFAMILY SSF48008 87 236 8.89E-19 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal VAPA_1c18330 6622065fc99d66f0c92cff13c765d87e 257 Pfam PF00392 Bacterial regulatory proteins, gntR family 22 80 5.1E-15 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_1c18330 6622065fc99d66f0c92cff13c765d87e 257 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 54 70 1.0E-5 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_1c18330 6622065fc99d66f0c92cff13c765d87e 257 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 40 54 1.0E-5 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_1c18330 6622065fc99d66f0c92cff13c765d87e 257 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 51 70 7.8E-5 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 VAPA_1c18330 6622065fc99d66f0c92cff13c765d87e 257 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 40 51 7.8E-5 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 VAPA_1c18330 6622065fc99d66f0c92cff13c765d87e 257 SUPERFAMILY SSF46785 21 108 5.25E-17 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c18330 6622065fc99d66f0c92cff13c765d87e 257 Gene3D G3DSA:1.20.120.530 80 237 1.3E-24 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal VAPA_1c18330 6622065fc99d66f0c92cff13c765d87e 257 SMART SM00895 90 227 3.3E-19 T 12-10-2018 IPR011711 GntR, C-terminal VAPA_1c18330 6622065fc99d66f0c92cff13c765d87e 257 Pfam PF07729 FCD domain 90 224 5.6E-18 T 12-10-2018 IPR011711 GntR, C-terminal VAPA_1c18330 6622065fc99d66f0c92cff13c765d87e 257 SMART SM00345 22 80 4.5E-13 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_1c18330 6622065fc99d66f0c92cff13c765d87e 257 Gene3D G3DSA:1.10.10.10 18 79 1.0E-18 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c44060 fcf74b47113bfe5e2f4966ecb3ddab21 223 Hamap MF_01385 Urease accessory protein UreF [ureF]. 6 223 30.714 T 12-10-2018 IPR002639 Urease accessory protein UreF GO:0006807|GO:0016151 VAPA_1c44060 fcf74b47113bfe5e2f4966ecb3ddab21 223 Gene3D G3DSA:1.10.4190.10 2 201 8.7E-53 T 12-10-2018 IPR038277 UreF domain superfamily VAPA_1c44060 fcf74b47113bfe5e2f4966ecb3ddab21 223 Pfam PF01730 UreF 38 181 1.5E-47 T 12-10-2018 IPR002639 Urease accessory protein UreF GO:0006807|GO:0016151 VAPA_1c44060 fcf74b47113bfe5e2f4966ecb3ddab21 223 PIRSF PIRSF009467 3 223 5.4E-60 T 12-10-2018 IPR002639 Urease accessory protein UreF GO:0006807|GO:0016151 VAPA_1c53540 697c529d848fab3a8a862177c3ef3ab4 293 SUPERFAMILY SSF88659 84 161 1.16E-10 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like VAPA_1c53540 697c529d848fab3a8a862177c3ef3ab4 293 Pfam PF04542 Sigma-70 region 2 10 70 1.3E-13 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 VAPA_1c53540 697c529d848fab3a8a862177c3ef3ab4 293 Pfam PF08281 Sigma-70, region 4 107 157 7.5E-12 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 VAPA_1c53540 697c529d848fab3a8a862177c3ef3ab4 293 Gene3D G3DSA:1.10.1740.10 7 69 3.8E-9 T 12-10-2018 VAPA_1c53540 697c529d848fab3a8a862177c3ef3ab4 293 Gene3D G3DSA:3.10.450.50 168 288 1.2E-5 T 12-10-2018 VAPA_1c53540 697c529d848fab3a8a862177c3ef3ab4 293 SUPERFAMILY SSF54427 169 287 2.37E-16 T 12-10-2018 IPR032710 NTF2-like domain superfamily VAPA_1c53540 697c529d848fab3a8a862177c3ef3ab4 293 Gene3D G3DSA:1.10.10.10 103 162 5.0E-11 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c53540 697c529d848fab3a8a862177c3ef3ab4 293 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 12 161 1.1E-17 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 VAPA_1c53540 697c529d848fab3a8a862177c3ef3ab4 293 TIGRFAM TIGR02957 SigX4: RNA polymerase sigma-70 factor, TIGR02957 family 8 286 4.7E-108 T 12-10-2018 IPR014303 RNA polymerase sigma-70, ECF type VAPA_1c53540 697c529d848fab3a8a862177c3ef3ab4 293 SUPERFAMILY SSF88946 9 88 1.29E-12 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 VAPA_2c01530 1c2b023b62b9313c2f68bc8b73de431a 135 SUPERFAMILY SSF54593 1 132 6.71E-27 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase VAPA_2c01530 1c2b023b62b9313c2f68bc8b73de431a 135 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 5 129 1.5E-13 T 12-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain VAPA_2c01530 1c2b023b62b9313c2f68bc8b73de431a 135 Gene3D G3DSA:3.10.180.10 2 134 2.0E-42 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase VAPA_2c03170 8daccf0c8bb18b664ff0eea8cf30c41b 737 Pfam PF06715 Gp5 C-terminal repeat (3 copies) 549 572 1.0E-4 T 12-10-2018 IPR010609 Gp5, C-terminal VAPA_2c03170 8daccf0c8bb18b664ff0eea8cf30c41b 737 Pfam PF06715 Gp5 C-terminal repeat (3 copies) 574 596 7.9E-6 T 12-10-2018 IPR010609 Gp5, C-terminal VAPA_2c03170 8daccf0c8bb18b664ff0eea8cf30c41b 737 Gene3D G3DSA:2.30.110.50 32 350 2.8E-95 T 12-10-2018 VAPA_2c03170 8daccf0c8bb18b664ff0eea8cf30c41b 737 Pfam PF05954 Phage late control gene D protein (GPD) 37 350 1.4E-84 T 12-10-2018 VAPA_2c03170 8daccf0c8bb18b664ff0eea8cf30c41b 737 TIGRFAM TIGR03361 VI_Rhs_Vgr: type VI secretion system Vgr family protein 26 543 1.9E-164 T 12-10-2018 IPR017847 Type VI secretion system, RhsGE-associated Vgr family subset VAPA_2c03170 8daccf0c8bb18b664ff0eea8cf30c41b 737 Gene3D G3DSA:3.30.1920.30 245 307 2.8E-95 T 12-10-2018 VAPA_2c03170 8daccf0c8bb18b664ff0eea8cf30c41b 737 TIGRFAM TIGR01646 vgr_GE: Rhs element Vgr protein 31 526 7.6E-134 T 12-10-2018 IPR006533 Type VI secretion system, RhsGE-associated Vgr protein VAPA_2c03170 8daccf0c8bb18b664ff0eea8cf30c41b 737 SUPERFAMILY SSF69349 462 630 7.3E-52 T 12-10-2018 VAPA_2c03170 8daccf0c8bb18b664ff0eea8cf30c41b 737 SUPERFAMILY SSF69349 590 724 1.73E-18 T 12-10-2018 VAPA_2c03170 8daccf0c8bb18b664ff0eea8cf30c41b 737 SUPERFAMILY SSF69279 215 378 7.82E-32 T 12-10-2018 VAPA_2c03170 8daccf0c8bb18b664ff0eea8cf30c41b 737 Gene3D G3DSA:3.55.50.10 119 209 2.8E-95 T 12-10-2018 VAPA_2c03170 8daccf0c8bb18b664ff0eea8cf30c41b 737 Gene3D G3DSA:2.40.50.230 375 477 4.6E-43 T 12-10-2018 IPR037026 Vgr protein, OB-fold domain superfamily VAPA_2c03170 8daccf0c8bb18b664ff0eea8cf30c41b 737 SUPERFAMILY SSF69255 384 472 4.45E-33 T 12-10-2018 VAPA_2c03170 8daccf0c8bb18b664ff0eea8cf30c41b 737 SUPERFAMILY SSF69279 24 205 9.78E-49 T 12-10-2018 VAPA_1c30150 e6c70a5826afcb95870d57fd39aa0d5a 329 SUPERFAMILY SSF53850 115 293 9.19E-13 T 12-10-2018 VAPA_1c30150 e6c70a5826afcb95870d57fd39aa0d5a 329 Gene3D G3DSA:3.40.190.10 130 254 1.5E-106 T 12-10-2018 VAPA_1c30150 e6c70a5826afcb95870d57fd39aa0d5a 329 Gene3D G3DSA:3.40.190.150 33 319 1.5E-106 T 12-10-2018 VAPA_1c30150 e6c70a5826afcb95870d57fd39aa0d5a 329 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 53 324 1.4E-81 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c30150 e6c70a5826afcb95870d57fd39aa0d5a 329 PIRSF PIRSF017082 1 328 3.2E-73 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c08450 e113b5ea34442b5ca5f17c97f5be0a47 464 PIRSF PIRSF006066 1 229 3.8E-70 T 12-10-2018 IPR004681 TRAP transporter large membrane protein DctM GO:0016021 VAPA_1c08450 e113b5ea34442b5ca5f17c97f5be0a47 464 PIRSF PIRSF006066 239 464 6.5E-65 T 12-10-2018 IPR004681 TRAP transporter large membrane protein DctM GO:0016021 VAPA_1c08450 e113b5ea34442b5ca5f17c97f5be0a47 464 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 5 454 1.7E-130 T 12-10-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit VAPA_1c03890 088def5fd1d99f50842d914ab88e42c5 387 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 125 137 - T 12-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 VAPA_1c03890 088def5fd1d99f50842d914ab88e42c5 387 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 229 385 1.4E-41 T 12-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 VAPA_1c03890 088def5fd1d99f50842d914ab88e42c5 387 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 123 217 9.0E-26 T 12-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 VAPA_1c03890 088def5fd1d99f50842d914ab88e42c5 387 Gene3D G3DSA:1.20.140.10 234 387 2.7E-42 T 12-10-2018 VAPA_1c03890 088def5fd1d99f50842d914ab88e42c5 387 PIRSF PIRSF016578 131 386 1.7E-12 T 12-10-2018 VAPA_1c03890 088def5fd1d99f50842d914ab88e42c5 387 PIRSF PIRSF016578 2 95 0.76 T 12-10-2018 VAPA_1c03890 088def5fd1d99f50842d914ab88e42c5 387 Gene3D G3DSA:2.40.110.10 122 233 3.2E-41 T 12-10-2018 VAPA_1c03890 088def5fd1d99f50842d914ab88e42c5 387 SUPERFAMILY SSF47203 227 385 2.09E-42 T 12-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 VAPA_1c03890 088def5fd1d99f50842d914ab88e42c5 387 Gene3D G3DSA:1.10.540.10 6 121 5.0E-28 T 12-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 VAPA_1c03890 088def5fd1d99f50842d914ab88e42c5 387 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 9 119 4.2E-21 T 12-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 VAPA_1c03890 088def5fd1d99f50842d914ab88e42c5 387 SUPERFAMILY SSF56645 2 242 4.71E-73 T 12-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 VAPA_1c22070 86dcb8f3de525c2732feb63113e93b91 285 TIGRFAM TIGR04553 ABC_peri_selen: putative selenate ABC transporter periplasmic binding protein 27 285 2.5E-124 T 12-10-2018 IPR030836 Putative ABC transporter periplasmic binding protein PhnD-like VAPA_1c22070 86dcb8f3de525c2732feb63113e93b91 285 Gene3D G3DSA:3.40.190.10 32 248 8.9E-62 T 12-10-2018 VAPA_1c22070 86dcb8f3de525c2732feb63113e93b91 285 SUPERFAMILY SSF53850 48 233 1.44E-35 T 12-10-2018 VAPA_1c22070 86dcb8f3de525c2732feb63113e93b91 285 TIGRFAM TIGR01098 3A0109s03R: phosphate/phosphite/phosphonate ABC transporter, periplasmic binding protein 11 244 2.2E-68 T 12-10-2018 IPR005770 Phosphate/phosphite/phosphonate ABC transporter, periplasmic binding protein GO:0043190|GO:0055085 VAPA_1c22070 86dcb8f3de525c2732feb63113e93b91 285 Gene3D G3DSA:3.40.190.10 112 219 8.9E-62 T 12-10-2018 VAPA_1c22070 86dcb8f3de525c2732feb63113e93b91 285 Pfam PF12974 ABC transporter, phosphonate, periplasmic substrate-binding protein 30 271 3.5E-70 T 12-10-2018 VAPA_1c22070 86dcb8f3de525c2732feb63113e93b91 285 SMART SM00062 27 254 0.0032 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF VAPA_1c42130 08da38e5bf764dc4ebb696e9b2f18aee 207 Pfam PF13247 4Fe-4S dicluster domain 52 124 7.2E-10 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain VAPA_1c42130 08da38e5bf764dc4ebb696e9b2f18aee 207 Gene3D G3DSA:3.30.70.20 5 169 6.2E-36 T 12-10-2018 VAPA_1c42130 08da38e5bf764dc4ebb696e9b2f18aee 207 SUPERFAMILY SSF54862 1 180 4.81E-50 T 12-10-2018 VAPA_1c42130 08da38e5bf764dc4ebb696e9b2f18aee 207 Gene3D G3DSA:3.30.70.20 61 118 6.2E-36 T 12-10-2018 VAPA_1c42130 08da38e5bf764dc4ebb696e9b2f18aee 207 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 87 98 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site VAPA_1c42130 08da38e5bf764dc4ebb696e9b2f18aee 207 PRINTS PR00354 7Fe ferredoxin signature 55 65 5.4E-5 T 12-10-2018 IPR000813 7Fe ferredoxin GO:0009055 VAPA_1c42130 08da38e5bf764dc4ebb696e9b2f18aee 207 PRINTS PR00354 7Fe ferredoxin signature 82 99 5.4E-5 T 12-10-2018 IPR000813 7Fe ferredoxin GO:0009055 VAPA_1c42130 08da38e5bf764dc4ebb696e9b2f18aee 207 PRINTS PR00354 7Fe ferredoxin signature 65 75 5.4E-5 T 12-10-2018 IPR000813 7Fe ferredoxin GO:0009055 VAPA_1c23040 85e50a27031f2997c943d48c817e598e 165 Gene3D G3DSA:3.30.70.920 61 145 9.0E-14 T 12-10-2018 VAPA_1c23040 85e50a27031f2997c943d48c817e598e 165 SUPERFAMILY SSF54909 73 140 5.63E-10 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel VAPA_1c23040 85e50a27031f2997c943d48c817e598e 165 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 36 55 9.5E-13 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 VAPA_1c23040 85e50a27031f2997c943d48c817e598e 165 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 9 25 9.5E-13 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 VAPA_1c23040 85e50a27031f2997c943d48c817e598e 165 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 25 36 9.5E-13 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 VAPA_1c23040 85e50a27031f2997c943d48c817e598e 165 Gene3D G3DSA:1.10.10.10 4 60 3.1E-23 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c23040 85e50a27031f2997c943d48c817e598e 165 Pfam PF01037 Lrp/AsnC ligand binding domain 76 138 3.7E-8 T 12-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain VAPA_1c23040 85e50a27031f2997c943d48c817e598e 165 Pfam PF13404 AsnC-type helix-turn-helix domain 9 50 4.2E-16 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 VAPA_1c23040 85e50a27031f2997c943d48c817e598e 165 SMART SM00344 9 113 1.5E-30 T 12-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 VAPA_1c23040 85e50a27031f2997c943d48c817e598e 165 SUPERFAMILY SSF46785 9 69 4.06E-18 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_2c01490 a4831fbb646e32309497892805d6d578 327 SUPERFAMILY SSF53850 114 287 1.79E-17 T 12-10-2018 VAPA_2c01490 a4831fbb646e32309497892805d6d578 327 Gene3D G3DSA:3.40.190.150 32 317 6.8E-111 T 12-10-2018 VAPA_2c01490 a4831fbb646e32309497892805d6d578 327 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 51 323 9.5E-87 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_2c01490 a4831fbb646e32309497892805d6d578 327 PIRSF PIRSF017082 1 326 8.8E-85 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_2c01490 a4831fbb646e32309497892805d6d578 327 Gene3D G3DSA:3.40.190.10 129 252 6.8E-111 T 12-10-2018 VAPA_1c22610 753a2806af5ca2b686b862e05ddf4221 324 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 47 318 8.7E-80 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c22610 753a2806af5ca2b686b862e05ddf4221 324 Gene3D G3DSA:3.40.190.150 28 314 2.7E-98 T 12-10-2018 VAPA_1c22610 753a2806af5ca2b686b862e05ddf4221 324 SUPERFAMILY SSF53850 111 284 2.44E-9 T 12-10-2018 VAPA_1c22610 753a2806af5ca2b686b862e05ddf4221 324 Gene3D G3DSA:3.40.190.10 126 249 2.7E-98 T 12-10-2018 VAPA_1c22610 753a2806af5ca2b686b862e05ddf4221 324 PIRSF PIRSF017082 1 323 1.2E-68 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c38920 28eb15d31f947016e1801c49d7bdf218 435 PIRSF PIRSF001563 3 425 5.6E-103 T 12-10-2018 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 VAPA_1c38920 28eb15d31f947016e1801c49d7bdf218 435 Gene3D G3DSA:3.40.1190.10 2 287 1.9E-88 T 12-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 VAPA_1c38920 28eb15d31f947016e1801c49d7bdf218 435 ProSitePatterns PS01011 Folylpolyglutamate synthase signature 1. 46 69 - T 12-10-2018 IPR018109 Folylpolyglutamate synthetase, conserved site GO:0004326|GO:0005524|GO:0009396 Reactome: R-HSA-196757 VAPA_1c38920 28eb15d31f947016e1801c49d7bdf218 435 SUPERFAMILY SSF53623 6 284 2.86E-82 T 12-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 VAPA_1c38920 28eb15d31f947016e1801c49d7bdf218 435 Pfam PF08245 Mur ligase middle domain 48 221 1.1E-10 T 12-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 VAPA_1c38920 28eb15d31f947016e1801c49d7bdf218 435 TIGRFAM TIGR01499 folC: bifunctional protein FolC 27 420 4.7E-100 T 12-10-2018 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 VAPA_1c38920 28eb15d31f947016e1801c49d7bdf218 435 SUPERFAMILY SSF53244 286 421 2.38E-30 T 12-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 VAPA_1c38920 28eb15d31f947016e1801c49d7bdf218 435 Gene3D G3DSA:3.90.190.20 288 424 1.4E-31 T 12-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 VAPA_1c53690 0ec4cb556c2dc87204cae09c40cc7642 576 Pfam PF04932 O-Antigen ligase 201 359 6.5E-17 T 12-10-2018 IPR007016 O-antigen ligase-related VAPA_1c53690 0ec4cb556c2dc87204cae09c40cc7642 576 Pfam PF11846 Virulence factor membrane-bound polymerase, C-terminal 383 565 6.3E-51 T 12-10-2018 IPR021797 Virulence factor membrane-bound polymerase, C-terminal VAPA_1c53690 0ec4cb556c2dc87204cae09c40cc7642 576 Pfam PF15864 Protein glycosylation ligase 161 184 1.5E-10 T 12-10-2018 IPR031726 Protein glycosylation ligase domain VAPA_1c24520 3ed685b8ae79051372c0351b39a39219 360 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 135 352 2.8E-17 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 VAPA_1c24520 3ed685b8ae79051372c0351b39a39219 360 TIGRFAM TIGR02138 phosphate_pstC: phosphate ABC transporter, permease protein PstC 57 352 1.0E-93 T 12-10-2018 IPR011864 Phosphate ABC transporter, permease protein PstC GO:0005315|GO:0006817|GO:0016021 VAPA_1c24520 3ed685b8ae79051372c0351b39a39219 360 Gene3D G3DSA:1.10.3720.10 112 356 4.7E-30 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c24520 3ed685b8ae79051372c0351b39a39219 360 SUPERFAMILY SSF161098 73 344 1.96E-31 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c36250 6d1e52654841ec8959ce2a2480ddfc81 386 Gene3D G3DSA:3.40.640.10 3 386 3.0E-99 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 VAPA_1c36250 6d1e52654841ec8959ce2a2480ddfc81 386 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 230 243 - T 12-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 VAPA_1c36250 6d1e52654841ec8959ce2a2480ddfc81 386 SUPERFAMILY SSF53383 6 382 3.99E-100 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase VAPA_1c36250 6d1e52654841ec8959ce2a2480ddfc81 386 Pfam PF00155 Aminotransferase class I and II 35 378 2.6E-55 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 VAPA_1c29890 e00699f5f92aeea8117eac14498147d3 494 Pfam PF02321 Outer membrane efflux protein 75 262 6.4E-28 T 12-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 VAPA_1c29890 e00699f5f92aeea8117eac14498147d3 494 Pfam PF02321 Outer membrane efflux protein 288 469 1.8E-29 T 12-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 VAPA_1c29890 e00699f5f92aeea8117eac14498147d3 494 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 17 471 1.3E-113 T 12-10-2018 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0016020|GO:0022857|GO:0055085 VAPA_1c29890 e00699f5f92aeea8117eac14498147d3 494 Gene3D G3DSA:2.20.200.10 112 360 1.2E-127 T 12-10-2018 VAPA_1c29890 e00699f5f92aeea8117eac14498147d3 494 SUPERFAMILY SSF56954 8 474 5.23E-104 T 12-10-2018 VAPA_1c29890 e00699f5f92aeea8117eac14498147d3 494 Gene3D G3DSA:1.20.1600.10 65 472 1.2E-127 T 12-10-2018 VAPA_2c09180 1f7c6b1a7527de83e5bf5b6e7678e38a 356 Pfam PF12697 Alpha/beta hydrolase family 81 343 1.9E-15 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 VAPA_2c09180 1f7c6b1a7527de83e5bf5b6e7678e38a 356 SUPERFAMILY SSF53474 60 350 8.11E-50 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_2c09180 1f7c6b1a7527de83e5bf5b6e7678e38a 356 PRINTS PR00412 Epoxide hydrolase signature 105 120 1.1E-10 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 VAPA_2c09180 1f7c6b1a7527de83e5bf5b6e7678e38a 356 PRINTS PR00412 Epoxide hydrolase signature 85 103 1.1E-10 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 VAPA_2c09180 1f7c6b1a7527de83e5bf5b6e7678e38a 356 PRINTS PR00412 Epoxide hydrolase signature 326 348 1.1E-10 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 VAPA_2c09180 1f7c6b1a7527de83e5bf5b6e7678e38a 356 PRINTS PR00412 Epoxide hydrolase signature 153 166 1.1E-10 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 VAPA_2c09180 1f7c6b1a7527de83e5bf5b6e7678e38a 356 PRINTS PR00412 Epoxide hydrolase signature 167 180 1.1E-10 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 VAPA_2c09180 1f7c6b1a7527de83e5bf5b6e7678e38a 356 Gene3D G3DSA:3.40.50.1820 52 348 3.3E-75 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_2c07620 335b8096dba303d2cf61f1acb455e330 225 Pfam PF04909 Amidohydrolase 3 219 3.6E-28 T 12-10-2018 IPR006680 Amidohydrolase-related GO:0016787 VAPA_2c07620 335b8096dba303d2cf61f1acb455e330 225 Gene3D G3DSA:3.20.20.140 1 221 7.4E-60 T 12-10-2018 VAPA_2c07620 335b8096dba303d2cf61f1acb455e330 225 SUPERFAMILY SSF51556 1 219 2.98E-56 T 12-10-2018 IPR032466 Metal-dependent hydrolase VAPA_1c39780 a1fc3f4b75e6cc4980c8063218ee73f7 793 Pfam PF10106 Uncharacterized protein conserved in bacteria (DUF2345) 619 764 1.9E-43 T 12-10-2018 IPR018769 Domain of unknown function DUF2345, Vgr C-terminal VAPA_1c39780 a1fc3f4b75e6cc4980c8063218ee73f7 793 TIGRFAM TIGR03361 VI_Rhs_Vgr: type VI secretion system Vgr family protein 6 502 3.5E-168 T 12-10-2018 IPR017847 Type VI secretion system, RhsGE-associated Vgr family subset VAPA_1c39780 a1fc3f4b75e6cc4980c8063218ee73f7 793 Gene3D G3DSA:3.30.1920.30 223 285 7.6E-112 T 12-10-2018 VAPA_1c39780 a1fc3f4b75e6cc4980c8063218ee73f7 793 TIGRFAM TIGR01646 vgr_GE: Rhs element Vgr protein 17 503 7.7E-145 T 12-10-2018 IPR006533 Type VI secretion system, RhsGE-associated Vgr protein VAPA_1c39780 a1fc3f4b75e6cc4980c8063218ee73f7 793 Gene3D G3DSA:3.55.50.10 92 183 7.6E-112 T 12-10-2018 VAPA_1c39780 a1fc3f4b75e6cc4980c8063218ee73f7 793 SUPERFAMILY SSF69279 182 365 2.21E-42 T 12-10-2018 VAPA_1c39780 a1fc3f4b75e6cc4980c8063218ee73f7 793 SUPERFAMILY SSF69279 11 178 2.34E-58 T 12-10-2018 VAPA_1c39780 a1fc3f4b75e6cc4980c8063218ee73f7 793 Pfam PF13296 Putative type VI secretion system Rhs element Vgr 476 584 3.3E-33 T 12-10-2018 IPR028244 Putative type VI secretion system, Rhs element associated Vgr domain VAPA_1c39780 a1fc3f4b75e6cc4980c8063218ee73f7 793 SUPERFAMILY SSF69255 365 453 2.62E-33 T 12-10-2018 VAPA_1c39780 a1fc3f4b75e6cc4980c8063218ee73f7 793 Gene3D G3DSA:2.30.110.50 9 330 7.6E-112 T 12-10-2018 VAPA_1c39780 a1fc3f4b75e6cc4980c8063218ee73f7 793 SUPERFAMILY SSF69349 443 496 3.06E-8 T 12-10-2018 VAPA_1c39780 a1fc3f4b75e6cc4980c8063218ee73f7 793 Gene3D G3DSA:2.40.50.230 356 458 6.5E-44 T 12-10-2018 IPR037026 Vgr protein, OB-fold domain superfamily VAPA_1c39780 a1fc3f4b75e6cc4980c8063218ee73f7 793 Pfam PF05954 Phage late control gene D protein (GPD) 23 329 2.9E-98 T 12-10-2018 VAPA_1c06080 ecb7f85c10f17de54dbe8952bde6f4bf 965 TIGRFAM TIGR03361 VI_Rhs_Vgr: type VI secretion system Vgr family protein 7 343 3.9E-60 T 12-10-2018 IPR017847 Type VI secretion system, RhsGE-associated Vgr family subset VAPA_1c06080 ecb7f85c10f17de54dbe8952bde6f4bf 965 TIGRFAM TIGR03361 VI_Rhs_Vgr: type VI secretion system Vgr family protein 394 567 2.0E-82 T 12-10-2018 IPR017847 Type VI secretion system, RhsGE-associated Vgr family subset VAPA_1c06080 ecb7f85c10f17de54dbe8952bde6f4bf 965 Gene3D G3DSA:3.55.50.10 99 195 2.0E-79 T 12-10-2018 VAPA_1c06080 ecb7f85c10f17de54dbe8952bde6f4bf 965 Pfam PF05954 Phage late control gene D protein (GPD) 26 334 8.4E-66 T 12-10-2018 VAPA_1c06080 ecb7f85c10f17de54dbe8952bde6f4bf 965 Gene3D G3DSA:2.40.50.230 402 504 2.1E-45 T 12-10-2018 IPR037026 Vgr protein, OB-fold domain superfamily VAPA_1c06080 ecb7f85c10f17de54dbe8952bde6f4bf 965 SUPERFAMILY SSF69279 201 411 5.95E-19 T 12-10-2018 VAPA_1c06080 ecb7f85c10f17de54dbe8952bde6f4bf 965 SUPERFAMILY SSF69279 6 189 2.04E-41 T 12-10-2018 VAPA_1c06080 ecb7f85c10f17de54dbe8952bde6f4bf 965 Gene3D G3DSA:3.30.1920.30 230 292 2.0E-79 T 12-10-2018 VAPA_1c06080 ecb7f85c10f17de54dbe8952bde6f4bf 965 SUPERFAMILY SSF69349 489 691 3.14E-32 T 12-10-2018 VAPA_1c06080 ecb7f85c10f17de54dbe8952bde6f4bf 965 Gene3D G3DSA:2.30.110.50 12 338 2.0E-79 T 12-10-2018 VAPA_1c06080 ecb7f85c10f17de54dbe8952bde6f4bf 965 SUPERFAMILY SSF69255 413 499 1.05E-33 T 12-10-2018 VAPA_1c06080 ecb7f85c10f17de54dbe8952bde6f4bf 965 TIGRFAM TIGR01646 vgr_GE: Rhs element Vgr protein 22 548 9.3E-111 T 12-10-2018 IPR006533 Type VI secretion system, RhsGE-associated Vgr protein VAPA_2c01820 6ef5eb7b32f54ee666a052fa262a2996 323 PIRSF PIRSF017082 1 323 1.8E-72 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_2c01820 6ef5eb7b32f54ee666a052fa262a2996 323 Gene3D G3DSA:3.40.190.10 125 248 1.9E-106 T 12-10-2018 VAPA_2c01820 6ef5eb7b32f54ee666a052fa262a2996 323 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 47 318 6.9E-91 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_2c01820 6ef5eb7b32f54ee666a052fa262a2996 323 SUPERFAMILY SSF53850 90 286 4.67E-12 T 12-10-2018 VAPA_2c01820 6ef5eb7b32f54ee666a052fa262a2996 323 Gene3D G3DSA:3.40.190.150 28 313 1.9E-106 T 12-10-2018 VAPA_1c16460 ccf1ed0f9e76d5412827ccfb5c4dcbaf 486 Gene3D G3DSA:3.20.20.140 61 415 5.8E-198 T 12-10-2018 VAPA_1c16460 ccf1ed0f9e76d5412827ccfb5c4dcbaf 486 SUPERFAMILY SSF51338 8 476 4.03E-20 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 VAPA_1c16460 ccf1ed0f9e76d5412827ccfb5c4dcbaf 486 Gene3D G3DSA:3.30.1490.130 289 345 5.8E-198 T 12-10-2018 IPR023100 D-aminoacylase, insert domain superfamily GO:0016811 VAPA_1c16460 ccf1ed0f9e76d5412827ccfb5c4dcbaf 486 SUPERFAMILY SSF51556 62 420 5.95E-85 T 12-10-2018 IPR032466 Metal-dependent hydrolase VAPA_1c16460 ccf1ed0f9e76d5412827ccfb5c4dcbaf 486 Pfam PF07969 Amidohydrolase family 316 464 3.0E-14 T 12-10-2018 IPR013108 Amidohydrolase 3 VAPA_1c16460 ccf1ed0f9e76d5412827ccfb5c4dcbaf 486 Pfam PF07969 Amidohydrolase family 51 250 4.9E-17 T 12-10-2018 IPR013108 Amidohydrolase 3 VAPA_1c16460 ccf1ed0f9e76d5412827ccfb5c4dcbaf 486 Gene3D G3DSA:2.30.40.10 8 434 5.8E-198 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 VAPA_1c22740 09d1496633ebeb1d930822e83cf9de42 324 Gene3D G3DSA:3.40.190.10 126 249 3.1E-99 T 12-10-2018 VAPA_1c22740 09d1496633ebeb1d930822e83cf9de42 324 SUPERFAMILY SSF53850 119 285 6.89E-11 T 12-10-2018 VAPA_1c22740 09d1496633ebeb1d930822e83cf9de42 324 PIRSF PIRSF017082 4 324 2.9E-71 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c22740 09d1496633ebeb1d930822e83cf9de42 324 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 47 321 1.2E-81 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c22740 09d1496633ebeb1d930822e83cf9de42 324 Gene3D G3DSA:3.40.190.150 28 314 3.1E-99 T 12-10-2018 VAPA_1c14860 c44bed644ec44b39941ca5807e2fbdb6 414 TIGRFAM TIGR03150 fabF: beta-ketoacyl-acyl-carrier-protein synthase II 4 412 3.2E-197 T 12-10-2018 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 VAPA_1c14860 c44bed644ec44b39941ca5807e2fbdb6 414 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 159 175 - T 12-10-2018 IPR018201 Beta-ketoacyl synthase, active site VAPA_1c14860 c44bed644ec44b39941ca5807e2fbdb6 414 Gene3D G3DSA:3.40.47.10 1 259 8.6E-98 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 VAPA_1c14860 c44bed644ec44b39941ca5807e2fbdb6 414 Gene3D G3DSA:3.40.47.10 261 403 3.0E-50 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 VAPA_1c14860 c44bed644ec44b39941ca5807e2fbdb6 414 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 259 371 9.0E-36 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal VAPA_1c14860 c44bed644ec44b39941ca5807e2fbdb6 414 SUPERFAMILY SSF53901 3 256 8.99E-82 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 VAPA_1c14860 c44bed644ec44b39941ca5807e2fbdb6 414 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 4 251 1.8E-63 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal VAPA_1c14860 c44bed644ec44b39941ca5807e2fbdb6 414 SUPERFAMILY SSF53901 218 413 6.53E-70 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 VAPA_1c14860 c44bed644ec44b39941ca5807e2fbdb6 414 SMART SM00825 Beta-ketoacyl synthase 6 414 2.6E-18 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain VAPA_1c14860 c44bed644ec44b39941ca5807e2fbdb6 414 PIRSF PIRSF000447 1 414 7.0E-185 T 12-10-2018 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 VAPA_2c11220 fd04816cfc6382358af8c0251b4b9341 414 Gene3D G3DSA:3.30.9.10 136 359 8.0E-45 T 12-10-2018 VAPA_2c11220 fd04816cfc6382358af8c0251b4b9341 414 Gene3D G3DSA:3.50.50.60 1 69 7.7E-9 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_2c11220 fd04816cfc6382358af8c0251b4b9341 414 SUPERFAMILY SSF54373 271 357 1.02E-10 T 12-10-2018 VAPA_2c11220 fd04816cfc6382358af8c0251b4b9341 414 Pfam PF01266 FAD dependent oxidoreductase 5 396 1.3E-47 T 12-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 VAPA_2c11220 fd04816cfc6382358af8c0251b4b9341 414 SUPERFAMILY SSF51905 4 414 7.77E-44 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_2c11220 fd04816cfc6382358af8c0251b4b9341 414 Gene3D G3DSA:3.50.50.60 116 403 8.0E-45 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c12020 aa35c1b228bd82e4bf24979676df593b 180 PIRSF PIRSF016481 1 179 5.4E-41 T 12-10-2018 IPR007446 Pilus assembly protein PilP VAPA_1c12020 aa35c1b228bd82e4bf24979676df593b 180 Gene3D G3DSA:2.30.30.830 84 176 8.2E-31 T 12-10-2018 VAPA_1c12020 aa35c1b228bd82e4bf24979676df593b 180 Pfam PF04351 Pilus assembly protein, PilP 27 175 3.1E-48 T 12-10-2018 IPR007446 Pilus assembly protein PilP VAPA_1c36690 42018af8f762c9fba6631d7a91e78efe 195 ProSitePatterns PS01078 Molybdenum cofactor biosynthesis proteins signature 1. 71 84 - T 12-10-2018 IPR008284 Molybdenum cofactor biosynthesis, conserved site GO:0006777 Reactome: R-HSA-947581 VAPA_1c36690 42018af8f762c9fba6631d7a91e78efe 195 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 7 148 4.0E-36 T 12-10-2018 IPR001453 MoaB/Mog domain VAPA_1c36690 42018af8f762c9fba6631d7a91e78efe 195 Pfam PF00994 Probable molybdopterin binding domain 10 149 2.3E-27 T 12-10-2018 IPR001453 MoaB/Mog domain VAPA_1c36690 42018af8f762c9fba6631d7a91e78efe 195 Gene3D G3DSA:3.40.980.10 6 195 1.8E-59 T 12-10-2018 IPR036425 MoaB/Mog-like domain superfamily VAPA_1c36690 42018af8f762c9fba6631d7a91e78efe 195 SMART SM00852 10 156 8.4E-25 T 12-10-2018 IPR001453 MoaB/Mog domain VAPA_1c36690 42018af8f762c9fba6631d7a91e78efe 195 SUPERFAMILY SSF53218 6 190 8.41E-46 T 12-10-2018 IPR036425 MoaB/Mog-like domain superfamily VAPA_1c29260 47d34e4a47118a24e401eec19557fc8a 445 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 258 366 3.2E-32 T 12-10-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 VAPA_1c29260 47d34e4a47118a24e401eec19557fc8a 445 SUPERFAMILY SSF53738 2 181 3.22E-45 T 12-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 VAPA_1c29260 47d34e4a47118a24e401eec19557fc8a 445 Gene3D G3DSA:3.40.120.10 2 154 2.5E-48 T 12-10-2018 VAPA_1c29260 47d34e4a47118a24e401eec19557fc8a 445 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 157 254 1.6E-17 T 12-10-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 VAPA_1c29260 47d34e4a47118a24e401eec19557fc8a 445 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 234 249 2.8E-11 T 12-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 VAPA_1c29260 47d34e4a47118a24e401eec19557fc8a 445 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 174 193 2.8E-11 T 12-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 VAPA_1c29260 47d34e4a47118a24e401eec19557fc8a 445 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 95 109 2.8E-11 T 12-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 VAPA_1c29260 47d34e4a47118a24e401eec19557fc8a 445 SUPERFAMILY SSF53738 156 256 3.14E-27 T 12-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 VAPA_1c29260 47d34e4a47118a24e401eec19557fc8a 445 Gene3D G3DSA:3.40.120.10 257 339 3.0E-58 T 12-10-2018 VAPA_1c29260 47d34e4a47118a24e401eec19557fc8a 445 Gene3D G3DSA:3.40.120.10 174 362 3.0E-58 T 12-10-2018 VAPA_1c29260 47d34e4a47118a24e401eec19557fc8a 445 TIGRFAM TIGR01455 glmM: phosphoglucosamine mutase 6 441 1.4E-173 T 12-10-2018 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 VAPA_1c29260 47d34e4a47118a24e401eec19557fc8a 445 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 3 135 2.4E-40 T 12-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 VAPA_1c29260 47d34e4a47118a24e401eec19557fc8a 445 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 373 441 4.0E-15 T 12-10-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 VAPA_1c29260 47d34e4a47118a24e401eec19557fc8a 445 SUPERFAMILY SSF53738 258 365 1.02E-29 T 12-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 VAPA_1c29260 47d34e4a47118a24e401eec19557fc8a 445 SUPERFAMILY SSF55957 357 443 1.57E-22 T 12-10-2018 IPR036900 Alpha-D-phosphohexomutase, C-terminal domain superfamily GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 VAPA_1c29260 47d34e4a47118a24e401eec19557fc8a 445 Hamap MF_01554_B Phosphoglucosamine mutase [glmM]. 2 444 45.191 T 12-10-2018 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 VAPA_1c29260 47d34e4a47118a24e401eec19557fc8a 445 Gene3D G3DSA:3.30.310.50 370 444 1.2E-24 T 12-10-2018 VAPA_2c05500 f58e54abb1f18bef48c948575ab5b05a 403 Gene3D G3DSA:3.40.50.10540 9 396 8.8E-121 T 12-10-2018 IPR023606 CoA-transferase family III domain superfamily VAPA_2c05500 f58e54abb1f18bef48c948575ab5b05a 403 Gene3D G3DSA:3.30.1540.10 237 329 8.8E-121 T 12-10-2018 VAPA_2c05500 f58e54abb1f18bef48c948575ab5b05a 403 Pfam PF02515 CoA-transferase family III 10 378 4.1E-119 T 12-10-2018 IPR003673 CoA-transferase family III GO:0003824 VAPA_2c05500 f58e54abb1f18bef48c948575ab5b05a 403 SUPERFAMILY SSF89796 7 402 6.15E-125 T 12-10-2018 IPR023606 CoA-transferase family III domain superfamily VAPA_1c33790 413a9d0e64f278ac31b4aed27be1c47f 316 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 12 69 5.8E-18 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c33790 413a9d0e64f278ac31b4aed27be1c47f 316 Gene3D G3DSA:1.10.10.10 10 95 1.7E-20 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c33790 413a9d0e64f278ac31b4aed27be1c47f 316 Gene3D G3DSA:3.40.190.290 98 306 2.3E-57 T 12-10-2018 VAPA_1c33790 413a9d0e64f278ac31b4aed27be1c47f 316 SUPERFAMILY SSF53850 95 308 3.62E-39 T 12-10-2018 VAPA_1c33790 413a9d0e64f278ac31b4aed27be1c47f 316 SUPERFAMILY SSF46785 12 93 2.6E-18 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c33790 413a9d0e64f278ac31b4aed27be1c47f 316 Pfam PF03466 LysR substrate binding domain 94 307 3.9E-39 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_1c06070 7a013f5fcbdab38db0733404f2a063f4 909 Gene3D G3DSA:3.40.50.300 595 812 2.0E-64 T 12-10-2018 VAPA_1c06070 7a013f5fcbdab38db0733404f2a063f4 909 SMART SM00382 230 375 1.5E-12 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c06070 7a013f5fcbdab38db0733404f2a063f4 909 SMART SM00382 642 786 2.1E-9 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c06070 7a013f5fcbdab38db0733404f2a063f4 909 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 691 709 1.5E-30 T 12-10-2018 IPR001270 ClpA/B family GO:0005524 VAPA_1c06070 7a013f5fcbdab38db0733404f2a063f4 909 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 753 767 1.5E-30 T 12-10-2018 IPR001270 ClpA/B family GO:0005524 VAPA_1c06070 7a013f5fcbdab38db0733404f2a063f4 909 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 646 664 1.5E-30 T 12-10-2018 IPR001270 ClpA/B family GO:0005524 VAPA_1c06070 7a013f5fcbdab38db0733404f2a063f4 909 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 720 738 1.5E-30 T 12-10-2018 IPR001270 ClpA/B family GO:0005524 VAPA_1c06070 7a013f5fcbdab38db0733404f2a063f4 909 TIGRFAM TIGR03345 VI_ClpV1: type VI secretion ATPase, ClpV1 family 13 898 0.0 T 12-10-2018 IPR017729 Type VI secretion system, ATPase ClpV1 VAPA_1c06070 7a013f5fcbdab38db0733404f2a063f4 909 Pfam PF07724 AAA domain (Cdc48 subfamily) 641 807 1.9E-37 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 VAPA_1c06070 7a013f5fcbdab38db0733404f2a063f4 909 Gene3D G3DSA:1.10.8.60 814 908 7.9E-13 T 12-10-2018 VAPA_1c06070 7a013f5fcbdab38db0733404f2a063f4 909 SMART SM01086 814 906 6.9E-15 T 12-10-2018 IPR019489 Clp ATPase, C-terminal VAPA_1c06070 7a013f5fcbdab38db0733404f2a063f4 909 Gene3D G3DSA:3.40.50.300 190 379 1.1E-65 T 12-10-2018 VAPA_1c06070 7a013f5fcbdab38db0733404f2a063f4 909 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 235 367 3.7E-11 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 VAPA_1c06070 7a013f5fcbdab38db0733404f2a063f4 909 SUPERFAMILY SSF81923 12 129 1.55E-20 T 12-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 VAPA_1c06070 7a013f5fcbdab38db0733404f2a063f4 909 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 326 338 - T 12-10-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 VAPA_1c06070 7a013f5fcbdab38db0733404f2a063f4 909 SUPERFAMILY SSF52540 591 878 9.29E-64 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c06070 7a013f5fcbdab38db0733404f2a063f4 909 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 814 892 7.8E-13 T 12-10-2018 IPR019489 Clp ATPase, C-terminal VAPA_1c06070 7a013f5fcbdab38db0733404f2a063f4 909 Gene3D G3DSA:3.40.50.300 380 589 2.1E-44 T 12-10-2018 VAPA_1c06070 7a013f5fcbdab38db0733404f2a063f4 909 Gene3D G3DSA:1.10.1780.10 1 161 3.4E-45 T 12-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 VAPA_1c06070 7a013f5fcbdab38db0733404f2a063f4 909 SUPERFAMILY SSF52540 191 527 4.24E-76 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c11370 a80d46ced24ab27274a7f1f4366553c5 529 Pfam PF00585 C-terminal regulatory domain of Threonine dehydratase 443 527 1.7E-23 T 12-10-2018 IPR001721 Threonine dehydratase, ACT-like domain KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 VAPA_1c11370 a80d46ced24ab27274a7f1f4366553c5 529 Pfam PF00585 C-terminal regulatory domain of Threonine dehydratase 328 361 9.3E-9 T 12-10-2018 IPR001721 Threonine dehydratase, ACT-like domain KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 VAPA_1c11370 a80d46ced24ab27274a7f1f4366553c5 529 Pfam PF00585 C-terminal regulatory domain of Threonine dehydratase 377 433 3.8E-10 T 12-10-2018 IPR001721 Threonine dehydratase, ACT-like domain KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 VAPA_1c11370 a80d46ced24ab27274a7f1f4366553c5 529 Gene3D G3DSA:3.40.50.1100 23 326 7.3E-136 T 12-10-2018 VAPA_1c11370 a80d46ced24ab27274a7f1f4366553c5 529 SUPERFAMILY SSF55021 434 527 6.41E-27 T 12-10-2018 VAPA_1c11370 a80d46ced24ab27274a7f1f4366553c5 529 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 51 64 - T 12-10-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 VAPA_1c11370 a80d46ced24ab27274a7f1f4366553c5 529 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 29 315 2.3E-76 T 12-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme VAPA_1c11370 a80d46ced24ab27274a7f1f4366553c5 529 Gene3D G3DSA:3.40.50.1100 59 155 7.3E-136 T 12-10-2018 VAPA_1c11370 a80d46ced24ab27274a7f1f4366553c5 529 TIGRFAM TIGR01124 ilvA_2Cterm: threonine ammonia-lyase, biosynthetic 13 527 1.1E-239 T 12-10-2018 IPR005787 Threonine dehydratase, biosynthetic GO:0004794|GO:0009097 KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 VAPA_1c11370 a80d46ced24ab27274a7f1f4366553c5 529 SUPERFAMILY SSF55021 336 437 2.15E-19 T 12-10-2018 VAPA_1c11370 a80d46ced24ab27274a7f1f4366553c5 529 SUPERFAMILY SSF53686 9 363 2.23E-101 T 12-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme VAPA_1c11370 a80d46ced24ab27274a7f1f4366553c5 529 Gene3D G3DSA:3.40.1020.10 337 529 3.5E-69 T 12-10-2018 IPR038110 Threonine dehydratase, ACT-like domain superfamily KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 VAPA_1c08830 49a877b4cc072650a3c257d376bf74fd 611 SUPERFAMILY SSF90123 32 356 1.7E-64 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 VAPA_1c08830 49a877b4cc072650a3c257d376bf74fd 611 Gene3D G3DSA:3.40.50.300 362 609 9.7E-96 T 12-10-2018 VAPA_1c08830 49a877b4cc072650a3c257d376bf74fd 611 ProSitePatterns PS00211 ABC transporters family signature. 505 519 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_1c08830 49a877b4cc072650a3c257d376bf74fd 611 Gene3D G3DSA:1.20.1560.10 37 356 3.2E-115 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 VAPA_1c08830 49a877b4cc072650a3c257d376bf74fd 611 SUPERFAMILY SSF52540 359 603 8.95E-92 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c08830 49a877b4cc072650a3c257d376bf74fd 611 SMART SM00382 393 585 6.9E-17 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c08830 49a877b4cc072650a3c257d376bf74fd 611 Pfam PF00005 ABC transporter 384 533 8.9E-35 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c08830 49a877b4cc072650a3c257d376bf74fd 611 Pfam PF00664 ABC transporter transmembrane region 46 320 1.7E-39 T 12-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 VAPA_1c40500 aa5d327789c80d01e4c6e5a104407b6e 116 PRINTS PR00189 Transthyretin signature 94 116 1.1E-7 T 12-10-2018 IPR000895 Transthyretin/hydroxyisourate hydrolase Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-6798695|Reactome: R-HSA-975634|Reactome: R-HSA-977225 VAPA_1c40500 aa5d327789c80d01e4c6e5a104407b6e 116 PRINTS PR00189 Transthyretin signature 2 22 1.1E-7 T 12-10-2018 IPR000895 Transthyretin/hydroxyisourate hydrolase Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-6798695|Reactome: R-HSA-975634|Reactome: R-HSA-977225 VAPA_1c40500 aa5d327789c80d01e4c6e5a104407b6e 116 ProSitePatterns PS00768 Transthyretin signature 1. 6 21 - T 12-10-2018 IPR023418 Transthyretin, thyroxine binding site Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-6798695|Reactome: R-HSA-975634|Reactome: R-HSA-977225 VAPA_1c40500 aa5d327789c80d01e4c6e5a104407b6e 116 SUPERFAMILY SSF49472 3 116 3.66E-38 T 12-10-2018 IPR036817 Transthyretin/hydroxyisourate hydrolase domain superfamily Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-6798695|Reactome: R-HSA-975634|Reactome: R-HSA-977225 VAPA_1c40500 aa5d327789c80d01e4c6e5a104407b6e 116 ProSitePatterns PS00769 Transthyretin signature 2. 99 111 - T 12-10-2018 IPR023419 Transthyretin, conserved site Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-6798695|Reactome: R-HSA-975634|Reactome: R-HSA-977225 VAPA_1c40500 aa5d327789c80d01e4c6e5a104407b6e 116 Pfam PF00576 HIUase/Transthyretin family 3 115 1.4E-34 T 12-10-2018 IPR023416 Transthyretin/hydroxyisourate hydrolase domain Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-6798695|Reactome: R-HSA-975634|Reactome: R-HSA-977225 VAPA_1c40500 aa5d327789c80d01e4c6e5a104407b6e 116 TIGRFAM TIGR02962 hdxy_isourate: hydroxyisourate hydrolase 3 116 2.1E-37 T 12-10-2018 IPR014306 Hydroxyisourate hydrolase GO:0006144|GO:0033971 KEGG: 00230+3.5.2.17|MetaCyc: PWY-5691|MetaCyc: PWY-7394|MetaCyc: PWY-7849 VAPA_1c40500 aa5d327789c80d01e4c6e5a104407b6e 116 Gene3D G3DSA:2.60.40.180 1 116 1.1E-37 T 12-10-2018 IPR036817 Transthyretin/hydroxyisourate hydrolase domain superfamily Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-6798695|Reactome: R-HSA-975634|Reactome: R-HSA-977225 VAPA_1c39060 990d69accce069c15f989de7546413a5 230 TIGRFAM TIGR00035 asp_race: aspartate racemase 2 229 2.7E-34 T 12-10-2018 IPR004380 Aspartate racemase GO:0006520|GO:0016855 VAPA_1c39060 990d69accce069c15f989de7546413a5 230 Pfam PF01177 Asp/Glu/Hydantoin racemase 6 224 1.4E-42 T 12-10-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 VAPA_1c39060 990d69accce069c15f989de7546413a5 230 SUPERFAMILY SSF53681 118 228 6.15E-23 T 12-10-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 VAPA_1c39060 990d69accce069c15f989de7546413a5 230 ProSitePatterns PS00924 Aspartate and glutamate racemases signature 2. 193 203 - T 12-10-2018 IPR033134 Asp/Glu racemase, active site 2 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 VAPA_1c39060 990d69accce069c15f989de7546413a5 230 Gene3D G3DSA:3.40.50.1860 104 215 1.1E-58 T 12-10-2018 VAPA_1c39060 990d69accce069c15f989de7546413a5 230 Gene3D G3DSA:3.40.50.1860 5 224 1.1E-58 T 12-10-2018 VAPA_1c39060 990d69accce069c15f989de7546413a5 230 SUPERFAMILY SSF53681 4 116 6.41E-20 T 12-10-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 VAPA_1c16520 f561c514847f0ca29fd1352fe02ca7dc 483 Pfam PF07171 MlrC C-terminus 297 471 2.3E-52 T 12-10-2018 IPR010799 Microcystin LR degradation protein MlrC, C-terminal VAPA_1c16520 f561c514847f0ca29fd1352fe02ca7dc 483 Pfam PF07364 Metallopeptidase family M81 2 288 4.6E-91 T 12-10-2018 IPR015995 Microcystin LR degradation protein MlrC, N-terminal VAPA_1c16520 f561c514847f0ca29fd1352fe02ca7dc 483 PIRSF PIRSF012702 1 483 6.8E-170 T 12-10-2018 IPR009197 Microcystin LR degradation protein MlrC VAPA_2c05660 a95e80d7569f9d74afdfa11a52268b2c 710 SUPERFAMILY SSF52210 157 298 7.33E-36 T 12-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 VAPA_2c05660 a95e80d7569f9d74afdfa11a52268b2c 710 Gene3D G3DSA:3.30.1490.20 505 582 6.4E-76 T 12-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 VAPA_2c05660 a95e80d7569f9d74afdfa11a52268b2c 710 SUPERFAMILY SSF56059 489 705 1.32E-41 T 12-10-2018 VAPA_2c05660 a95e80d7569f9d74afdfa11a52268b2c 710 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 163 300 3.3E-44 T 12-10-2018 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain VAPA_2c05660 a95e80d7569f9d74afdfa11a52268b2c 710 Pfam PF13380 CoA binding domain 17 142 5.2E-20 T 12-10-2018 IPR003781 CoA-binding GO:0048037 VAPA_2c05660 a95e80d7569f9d74afdfa11a52268b2c 710 Gene3D G3DSA:3.40.50.720 8 137 1.1E-40 T 12-10-2018 VAPA_2c05660 a95e80d7569f9d74afdfa11a52268b2c 710 Pfam PF13549 ATP-grasp domain 487 698 1.6E-62 T 12-10-2018 VAPA_2c05660 a95e80d7569f9d74afdfa11a52268b2c 710 Gene3D G3DSA:3.30.470.20 487 698 6.4E-76 T 12-10-2018 VAPA_2c05660 a95e80d7569f9d74afdfa11a52268b2c 710 SUPERFAMILY SSF52210 310 464 4.58E-24 T 12-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 VAPA_2c05660 a95e80d7569f9d74afdfa11a52268b2c 710 SMART SM00881 13 108 6.2E-36 T 12-10-2018 IPR003781 CoA-binding GO:0048037 VAPA_2c05660 a95e80d7569f9d74afdfa11a52268b2c 710 SUPERFAMILY SSF51735 10 138 9.2E-35 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_2c05660 a95e80d7569f9d74afdfa11a52268b2c 710 Gene3D G3DSA:3.40.50.261 308 469 9.5E-28 T 12-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 VAPA_2c05660 a95e80d7569f9d74afdfa11a52268b2c 710 Gene3D G3DSA:3.40.50.261 140 304 1.2E-45 T 12-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 VAPA_2c03960 2f8c97341e2c523f38b5d6f4125f6ff5 356 Gene3D G3DSA:2.40.50.100 49 82 2.9E-7 T 12-10-2018 VAPA_2c03960 2f8c97341e2c523f38b5d6f4125f6ff5 356 Pfam PF13533 Biotin-lipoyl like 51 94 1.1E-6 T 12-10-2018 IPR039562 Membrane fusion protein, biotin-lipoyl like domain VAPA_2c03960 2f8c97341e2c523f38b5d6f4125f6ff5 356 Pfam PF13437 HlyD family secretion protein 216 320 4.1E-13 T 12-10-2018 VAPA_2c03960 2f8c97341e2c523f38b5d6f4125f6ff5 356 Gene3D G3DSA:1.10.287.470 116 180 1.1E-6 T 12-10-2018 VAPA_2c03960 2f8c97341e2c523f38b5d6f4125f6ff5 356 SUPERFAMILY SSF111369 42 132 4.32E-6 T 12-10-2018 VAPA_2c03960 2f8c97341e2c523f38b5d6f4125f6ff5 356 Gene3D G3DSA:2.40.30.170 251 301 7.4E-16 T 12-10-2018 VAPA_2c03960 2f8c97341e2c523f38b5d6f4125f6ff5 356 Gene3D G3DSA:1.10.287.470 184 215 7.4E-16 T 12-10-2018 VAPA_2c03960 2f8c97341e2c523f38b5d6f4125f6ff5 356 Gene3D G3DSA:2.40.50.100 216 250 7.4E-16 T 12-10-2018 VAPA_2c03960 2f8c97341e2c523f38b5d6f4125f6ff5 356 Gene3D G3DSA:1.10.287.470 83 111 2.9E-7 T 12-10-2018 VAPA_2c03960 2f8c97341e2c523f38b5d6f4125f6ff5 356 SUPERFAMILY SSF111369 174 299 2.09E-8 T 12-10-2018 VAPA_1c48460 27c565beeae24b83c184885368f75aee 353 SUPERFAMILY SSF52768 3 348 1.97E-82 T 12-10-2018 IPR023696 Ureohydrolase domain superfamily VAPA_1c48460 27c565beeae24b83c184885368f75aee 353 PRINTS PR01270 Histone deacetylase superfamily signature 196 211 1.3E-11 T 12-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 VAPA_1c48460 27c565beeae24b83c184885368f75aee 353 PRINTS PR01270 Histone deacetylase superfamily signature 163 186 1.3E-11 T 12-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 VAPA_1c48460 27c565beeae24b83c184885368f75aee 353 PRINTS PR01270 Histone deacetylase superfamily signature 282 292 1.3E-11 T 12-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 VAPA_1c48460 27c565beeae24b83c184885368f75aee 353 Pfam PF00850 Histone deacetylase domain 32 345 7.0E-61 T 12-10-2018 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 VAPA_1c48460 27c565beeae24b83c184885368f75aee 353 Gene3D G3DSA:3.40.800.20 5 349 2.2E-115 T 12-10-2018 IPR037138 Histone deacetylase domain superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 VAPA_1c15760 d4c464e09bb60e282c99ee6e157b9e8f 634 SMART SM00490 360 441 1.0E-28 T 12-10-2018 IPR001650 Helicase, C-terminal VAPA_1c15760 d4c464e09bb60e282c99ee6e157b9e8f 634 Pfam PF00271 Helicase conserved C-terminal domain 343 441 3.8E-24 T 12-10-2018 IPR001650 Helicase, C-terminal VAPA_1c15760 d4c464e09bb60e282c99ee6e157b9e8f 634 Gene3D G3DSA:3.40.50.300 314 487 1.5E-45 T 12-10-2018 VAPA_1c15760 d4c464e09bb60e282c99ee6e157b9e8f 634 SMART SM00487 74 323 9.4E-49 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain VAPA_1c15760 d4c464e09bb60e282c99ee6e157b9e8f 634 SUPERFAMILY SSF52540 178 463 6.0E-66 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c15760 d4c464e09bb60e282c99ee6e157b9e8f 634 Pfam PF00270 DEAD/DEAH box helicase 79 295 1.7E-42 T 12-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 VAPA_1c15760 d4c464e09bb60e282c99ee6e157b9e8f 634 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 254 262 - T 12-10-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site VAPA_2c07190 02671b7563d7d0872bb010c299173268 227 SMART SM00862 149 225 6.5E-22 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 VAPA_2c07190 02671b7563d7d0872bb010c299173268 227 SMART SM00448 6 116 2.8E-39 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_2c07190 02671b7563d7d0872bb010c299173268 227 Pfam PF00072 Response regulator receiver domain 8 116 7.9E-26 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_2c07190 02671b7563d7d0872bb010c299173268 227 Gene3D G3DSA:1.10.10.10 135 227 7.1E-30 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_2c07190 02671b7563d7d0872bb010c299173268 227 Pfam PF00486 Transcriptional regulatory protein, C terminal 151 225 4.3E-22 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 VAPA_2c07190 02671b7563d7d0872bb010c299173268 227 Gene3D G3DSA:3.40.50.2300 1 129 1.6E-34 T 12-10-2018 VAPA_2c07190 02671b7563d7d0872bb010c299173268 227 SUPERFAMILY SSF52172 3 128 5.98E-40 T 12-10-2018 IPR011006 CheY-like superfamily VAPA_2c07190 02671b7563d7d0872bb010c299173268 227 SUPERFAMILY SSF46894 136 226 3.68E-24 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 VAPA_2c07680 289a7e7fcc3d1e18629ea18ccbbafdef 157 Gene3D G3DSA:3.10.20.30 2 75 6.2E-27 T 12-10-2018 IPR012675 Beta-grasp domain superfamily VAPA_2c07680 289a7e7fcc3d1e18629ea18ccbbafdef 157 Pfam PF01799 [2Fe-2S] binding domain 72 149 5.8E-23 T 12-10-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 VAPA_2c07680 289a7e7fcc3d1e18629ea18ccbbafdef 157 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 38 46 - T 12-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 VAPA_2c07680 289a7e7fcc3d1e18629ea18ccbbafdef 157 Gene3D G3DSA:1.10.150.120 79 157 6.2E-23 T 12-10-2018 VAPA_2c07680 289a7e7fcc3d1e18629ea18ccbbafdef 157 SUPERFAMILY SSF54292 4 75 6.95E-26 T 12-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 VAPA_2c07680 289a7e7fcc3d1e18629ea18ccbbafdef 157 SUPERFAMILY SSF47741 85 155 2.22E-25 T 12-10-2018 IPR036884 [2Fe-2S]-binding domain superfamily VAPA_2c07680 289a7e7fcc3d1e18629ea18ccbbafdef 157 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 5 58 1.1E-8 T 12-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 VAPA_1c18100 d545da07db8663e4573a855c1a29ed51 336 Gene3D G3DSA:2.130.10.10 1 334 2.0E-107 T 12-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 VAPA_1c18100 d545da07db8663e4573a855c1a29ed51 336 Pfam PF10282 Lactonase, 7-bladed beta-propeller 7 330 2.4E-77 T 12-10-2018 IPR019405 Lactonase, 7-bladed beta propeller VAPA_1c18100 d545da07db8663e4573a855c1a29ed51 336 SUPERFAMILY SSF51004 6 336 5.75E-40 T 12-10-2018 IPR011048 Cytochrome cd1-nitrite reductase-like, haem d1 domain superfamily VAPA_1c54970 be0a3f20ac7634e1f84118f624bd519a 196 SUPERFAMILY SSF54211 3 124 6.07E-37 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold VAPA_1c54970 be0a3f20ac7634e1f84118f624bd519a 196 Pfam PF01205 Uncharacterized protein family UPF0029 16 117 3.2E-27 T 12-10-2018 IPR001498 Impact, N-terminal VAPA_1c54970 be0a3f20ac7634e1f84118f624bd519a 196 SUPERFAMILY SSF54980 131 193 5.4E-9 T 12-10-2018 IPR035647 EF-G domain III/V-like VAPA_1c54970 be0a3f20ac7634e1f84118f624bd519a 196 Pfam PF09186 Domain of unknown function (DUF1949) 134 190 9.3E-12 T 12-10-2018 IPR015269 Uncharacterised domain UPF0029, Impact, C-terminal VAPA_1c54970 be0a3f20ac7634e1f84118f624bd519a 196 Gene3D G3DSA:3.30.230.30 2 123 8.7E-44 T 12-10-2018 IPR036956 Impact, N-terminal domain superfamily VAPA_2c11550 480d7cc318195597fd1bff7101b12477 210 TIGRFAM TIGR03292 PhnH_redo: phosphonate C-P lyase system protein PhnH 13 205 3.8E-50 T 12-10-2018 IPR008772 Bacterial phosphonate metabolism, PhnH GO:0019634 VAPA_2c11550 480d7cc318195597fd1bff7101b12477 210 Gene3D G3DSA:3.40.50.11310 7 208 1.1E-56 T 12-10-2018 IPR038058 PhnH-like superfamily VAPA_2c11550 480d7cc318195597fd1bff7101b12477 210 SUPERFAMILY SSF159709 19 207 1.05E-57 T 12-10-2018 IPR038058 PhnH-like superfamily VAPA_2c11550 480d7cc318195597fd1bff7101b12477 210 PIRSF PIRSF020680 3 210 1.8E-67 T 12-10-2018 IPR008772 Bacterial phosphonate metabolism, PhnH GO:0019634 VAPA_2c11550 480d7cc318195597fd1bff7101b12477 210 Pfam PF05845 Bacterial phosphonate metabolism protein (PhnH) 12 207 1.1E-63 T 12-10-2018 IPR008772 Bacterial phosphonate metabolism, PhnH GO:0019634 VAPA_1c51140 d7bb2ff35227ef4c8f0d132c9d8b1c64 248 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3 192 0.0012 T 12-10-2018 VAPA_1c51140 d7bb2ff35227ef4c8f0d132c9d8b1c64 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 1.4E-38 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c51140 d7bb2ff35227ef4c8f0d132c9d8b1c64 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 1.4E-38 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c51140 d7bb2ff35227ef4c8f0d132c9d8b1c64 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 1.4E-38 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c51140 d7bb2ff35227ef4c8f0d132c9d8b1c64 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 1.4E-38 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c51140 d7bb2ff35227ef4c8f0d132c9d8b1c64 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 1.4E-38 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c51140 d7bb2ff35227ef4c8f0d132c9d8b1c64 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 212 232 1.4E-38 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c51140 d7bb2ff35227ef4c8f0d132c9d8b1c64 248 Gene3D G3DSA:3.40.50.720 2 248 1.1E-76 T 12-10-2018 VAPA_1c51140 d7bb2ff35227ef4c8f0d132c9d8b1c64 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 79 90 1.1E-11 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c51140 d7bb2ff35227ef4c8f0d132c9d8b1c64 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 136 144 1.1E-11 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c51140 d7bb2ff35227ef4c8f0d132c9d8b1c64 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 157 176 1.1E-11 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c51140 d7bb2ff35227ef4c8f0d132c9d8b1c64 248 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 247 3.7E-52 T 12-10-2018 VAPA_1c51140 d7bb2ff35227ef4c8f0d132c9d8b1c64 248 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 144 172 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 VAPA_1c51140 d7bb2ff35227ef4c8f0d132c9d8b1c64 248 SUPERFAMILY SSF51735 3 247 8.24E-68 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c07470 97013a3c5cb4b4a20ca2c52598c79fe8 776 Gene3D G3DSA:3.30.565.10 599 761 7.0E-35 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_1c07470 97013a3c5cb4b4a20ca2c52598c79fe8 776 SUPERFAMILY SSF47384 524 599 6.67E-12 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 VAPA_1c07470 97013a3c5cb4b4a20ca2c52598c79fe8 776 SMART SM00091 399 465 8.9E-5 T 12-10-2018 IPR000014 PAS domain VAPA_1c07470 97013a3c5cb4b4a20ca2c52598c79fe8 776 SUPERFAMILY SSF55874 590 745 3.01E-31 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_1c07470 97013a3c5cb4b4a20ca2c52598c79fe8 776 SMART SM00304 333 385 2.7E-7 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 VAPA_1c07470 97013a3c5cb4b4a20ca2c52598c79fe8 776 PRINTS PR00344 Bacterial sensor protein C-terminal signature 686 700 6.4E-10 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c07470 97013a3c5cb4b4a20ca2c52598c79fe8 776 PRINTS PR00344 Bacterial sensor protein C-terminal signature 704 714 6.4E-10 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c07470 97013a3c5cb4b4a20ca2c52598c79fe8 776 PRINTS PR00344 Bacterial sensor protein C-terminal signature 715 733 6.4E-10 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c07470 97013a3c5cb4b4a20ca2c52598c79fe8 776 Gene3D G3DSA:1.10.287.130 522 597 1.4E-12 T 12-10-2018 VAPA_1c07470 97013a3c5cb4b4a20ca2c52598c79fe8 776 Gene3D G3DSA:3.30.450.20 389 521 9.6E-9 T 12-10-2018 VAPA_1c07470 97013a3c5cb4b4a20ca2c52598c79fe8 776 SMART SM00387 640 759 3.1E-28 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase VAPA_1c07470 97013a3c5cb4b4a20ca2c52598c79fe8 776 SUPERFAMILY SSF158472 335 382 1.96E-7 T 12-10-2018 VAPA_1c07470 97013a3c5cb4b4a20ca2c52598c79fe8 776 Pfam PF00512 His Kinase A (phospho-acceptor) domain 529 598 7.5E-11 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 VAPA_1c07470 97013a3c5cb4b4a20ca2c52598c79fe8 776 SMART SM00388 528 600 1.4E-12 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 VAPA_1c07470 97013a3c5cb4b4a20ca2c52598c79fe8 776 PIRSF PIRSF037532 4 763 2.8E-207 T 12-10-2018 IPR017232 Signal transduction histidine kinase, nitrogen fixation and metabolism regulator VAPA_1c07470 97013a3c5cb4b4a20ca2c52598c79fe8 776 Pfam PF00672 HAMP domain 335 381 2.0E-7 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 VAPA_1c07470 97013a3c5cb4b4a20ca2c52598c79fe8 776 Gene3D G3DSA:1.20.1480.50 297 388 2.1E-10 T 12-10-2018 VAPA_1c07470 97013a3c5cb4b4a20ca2c52598c79fe8 776 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 640 741 5.9E-17 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase VAPA_1c07470 97013a3c5cb4b4a20ca2c52598c79fe8 776 SUPERFAMILY SSF55785 391 478 2.47E-7 T 12-10-2018 IPR035965 PAS domain superfamily VAPA_1c18640 5643264ebb4b56f3560c276ff6356e3a 287 Pfam PF03641 Possible lysine decarboxylase 151 281 2.3E-34 T 12-10-2018 IPR031100 LOG family VAPA_1c18640 5643264ebb4b56f3560c276ff6356e3a 287 Gene3D G3DSA:3.40.50.450 49 284 4.3E-63 T 12-10-2018 VAPA_1c18640 5643264ebb4b56f3560c276ff6356e3a 287 SUPERFAMILY SSF102405 41 282 7.17E-53 T 12-10-2018 VAPA_1c18640 5643264ebb4b56f3560c276ff6356e3a 287 TIGRFAM TIGR00730 TIGR00730: TIGR00730 family protein 113 283 2.1E-34 T 12-10-2018 IPR005269 Cytokinin riboside 5'-monophosphate phosphoribohydrolase LOG VAPA_1c49210 034c771007d23952971e260e1a984547 157 SUPERFAMILY SSF54909 64 157 1.74E-21 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel VAPA_1c49210 034c771007d23952971e260e1a984547 157 SUPERFAMILY SSF46785 3 83 3.19E-18 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c49210 034c771007d23952971e260e1a984547 157 Pfam PF13412 Winged helix-turn-helix DNA-binding 4 50 1.5E-18 T 12-10-2018 VAPA_1c49210 034c771007d23952971e260e1a984547 157 Gene3D G3DSA:3.30.70.920 58 145 4.6E-28 T 12-10-2018 VAPA_1c49210 034c771007d23952971e260e1a984547 157 SMART SM00344 4 117 3.7E-35 T 12-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 VAPA_1c49210 034c771007d23952971e260e1a984547 157 Gene3D G3DSA:1.10.10.10 1 57 2.1E-23 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c49210 034c771007d23952971e260e1a984547 157 Pfam PF01037 Lrp/AsnC ligand binding domain 72 147 5.9E-24 T 12-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain VAPA_1c49210 034c771007d23952971e260e1a984547 157 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 31 50 1.8E-15 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 VAPA_1c49210 034c771007d23952971e260e1a984547 157 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 4 20 1.8E-15 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 VAPA_1c49210 034c771007d23952971e260e1a984547 157 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 20 31 1.8E-15 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 VAPA_1c33040 c35171ceb8891efc5eb00e10c134972e 1131 SMART SM00481 40 128 4.0E-9 T 12-10-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal VAPA_1c33040 c35171ceb8891efc5eb00e10c134972e 1131 SUPERFAMILY SSF89550 39 273 8.63E-11 T 12-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 VAPA_1c33040 c35171ceb8891efc5eb00e10c134972e 1131 Pfam PF01336 OB-fold nucleic acid binding domain 1038 1098 1.3E-6 T 12-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 VAPA_1c33040 c35171ceb8891efc5eb00e10c134972e 1131 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 336 770 9.8E-143 T 12-10-2018 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 VAPA_1c33040 c35171ceb8891efc5eb00e10c134972e 1131 Pfam PF14579 Helix-hairpin-helix motif 843 952 2.9E-19 T 12-10-2018 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 VAPA_1c33040 c35171ceb8891efc5eb00e10c134972e 1131 Gene3D G3DSA:3.20.20.140 7 311 9.3E-51 T 12-10-2018 VAPA_1c33040 c35171ceb8891efc5eb00e10c134972e 1131 Pfam PF02811 PHP domain 41 210 1.2E-9 T 12-10-2018 IPR004013 PHP domain GO:0003824 VAPA_1c33040 c35171ceb8891efc5eb00e10c134972e 1131 Hamap MF_01902 Error-prone DNA polymerase [dnaE2]. 39 1131 12.955 T 12-10-2018 IPR023073 DNA polymerase, error-prone GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 VAPA_1c33040 c35171ceb8891efc5eb00e10c134972e 1131 TIGRFAM TIGR00594 polc: DNA polymerase III, alpha subunit 40 1070 1.8E-151 T 12-10-2018 IPR004805 DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 VAPA_1c29490 3d56a709ea98e72c16dcbe4fd85e1941 247 Hamap MF_01139 Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) [uppS]. 8 229 37.211 T 12-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 VAPA_1c29490 3d56a709ea98e72c16dcbe4fd85e1941 247 TIGRFAM TIGR00055 uppS: di-trans,poly-cis-decaprenylcistransferase 8 228 2.9E-77 T 12-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 VAPA_1c29490 3d56a709ea98e72c16dcbe4fd85e1941 247 Gene3D G3DSA:3.40.1180.10 1 232 2.6E-86 T 12-10-2018 IPR036424 Decaprenyl diphosphate synthase-like superfamily GO:0016765 Reactome: R-HSA-446199 VAPA_1c29490 3d56a709ea98e72c16dcbe4fd85e1941 247 SUPERFAMILY SSF64005 7 224 2.35E-78 T 12-10-2018 IPR036424 Decaprenyl diphosphate synthase-like superfamily GO:0016765 Reactome: R-HSA-446199 VAPA_1c29490 3d56a709ea98e72c16dcbe4fd85e1941 247 Pfam PF01255 Putative undecaprenyl diphosphate synthase 15 228 2.2E-76 T 12-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 VAPA_1c29490 3d56a709ea98e72c16dcbe4fd85e1941 247 ProSitePatterns PS01066 Undecaprenyl pyrophosphate synthase family signature. 174 191 - T 12-10-2018 IPR018520 Di-trans-poly-cis-decaprenylcistransferase-like, conserved site GO:0016765 Reactome: R-HSA-446199|Reactome: R-HSA-4755609 VAPA_1c13130 66e6bee9ae88d4f4d01b1fb99a14ab6b 175 SUPERFAMILY SSF52141 17 171 3.27E-31 T 12-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 VAPA_1c13130 66e6bee9ae88d4f4d01b1fb99a14ab6b 175 Gene3D G3DSA:3.40.470.10 13 174 5.0E-50 T 12-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 VAPA_1c13130 66e6bee9ae88d4f4d01b1fb99a14ab6b 175 SMART SM00986 19 169 6.8E-7 T 12-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 VAPA_1c13130 66e6bee9ae88d4f4d01b1fb99a14ab6b 175 Pfam PF03167 Uracil DNA glycosylase superfamily 25 167 5.2E-6 T 12-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 VAPA_1c13130 66e6bee9ae88d4f4d01b1fb99a14ab6b 175 TIGRFAM TIGR04274 hypoxanDNAglyco: DNA-deoxyinosine glycosylase 16 165 7.4E-41 T 12-10-2018 IPR026353 Hypoxanthine-DNA glycosylase VAPA_1c13130 66e6bee9ae88d4f4d01b1fb99a14ab6b 175 SMART SM00987 19 169 6.8E-7 T 12-10-2018 VAPA_1c17920 89d5fd0ed38c4c23d055468d37e3749f 212 Gene3D G3DSA:3.40.30.10 2 80 9.1E-20 T 12-10-2018 VAPA_1c17920 89d5fd0ed38c4c23d055468d37e3749f 212 SUPERFAMILY SSF52833 1 87 3.6E-21 T 12-10-2018 IPR036249 Thioredoxin-like superfamily VAPA_1c17920 89d5fd0ed38c4c23d055468d37e3749f 212 SUPERFAMILY SSF47616 74 203 1.81E-21 T 12-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily VAPA_1c17920 89d5fd0ed38c4c23d055468d37e3749f 212 Pfam PF02798 Glutathione S-transferase, N-terminal domain 3 76 2.7E-12 T 12-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 VAPA_1c17920 89d5fd0ed38c4c23d055468d37e3749f 212 Gene3D G3DSA:1.20.1050.10 87 201 1.1E-21 T 12-10-2018 VAPA_1c17920 89d5fd0ed38c4c23d055468d37e3749f 212 Pfam PF00043 Glutathione S-transferase, C-terminal domain 105 198 3.0E-6 T 12-10-2018 IPR004046 Glutathione S-transferase, C-terminal VAPA_1c21130 85faf9eba0e99389d5f85a13424c991b 721 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 22 108 2.4E-21 T 12-10-2018 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 VAPA_1c21130 85faf9eba0e99389d5f85a13424c991b 721 SMART SM00642 173 579 1.2E-8 T 12-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 VAPA_1c21130 85faf9eba0e99389d5f85a13424c991b 721 SUPERFAMILY SSF51445 152 587 6.26E-135 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily VAPA_1c21130 85faf9eba0e99389d5f85a13424c991b 721 Gene3D G3DSA:2.60.40.10 5 151 5.6E-52 T 12-10-2018 IPR013783 Immunoglobulin-like fold VAPA_1c21130 85faf9eba0e99389d5f85a13424c991b 721 SUPERFAMILY SSF81296 15 162 7.28E-49 T 12-10-2018 IPR014756 Immunoglobulin E-set VAPA_1c21130 85faf9eba0e99389d5f85a13424c991b 721 Gene3D G3DSA:2.60.40.1180 599 716 9.2E-21 T 12-10-2018 IPR013780 Glycosyl hydrolase, all-beta VAPA_1c21130 85faf9eba0e99389d5f85a13424c991b 721 SUPERFAMILY SSF51011 601 714 2.64E-27 T 12-10-2018 VAPA_1c21130 85faf9eba0e99389d5f85a13424c991b 721 Pfam PF00128 Alpha amylase, catalytic domain 203 305 1.3E-10 T 12-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 VAPA_1c21130 85faf9eba0e99389d5f85a13424c991b 721 Gene3D G3DSA:3.20.20.80 153 593 6.1E-184 T 12-10-2018 VAPA_1c21130 85faf9eba0e99389d5f85a13424c991b 721 TIGRFAM TIGR02100 glgX_debranch: glycogen debranching enzyme GlgX 16 684 0.0 T 12-10-2018 IPR011837 Glycogen debranching enzyme, GlgX type GO:0004133|GO:0004553|GO:0005980 VAPA_1c37730 6be2a3009368f45b63aec0982452649a 224 SUPERFAMILY SSF55120 3 217 9.92E-58 T 12-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 VAPA_1c37730 6be2a3009368f45b63aec0982452649a 224 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 50 64 - T 12-10-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 VAPA_1c37730 6be2a3009368f45b63aec0982452649a 224 Pfam PF00849 RNA pseudouridylate synthase 12 165 2.4E-28 T 12-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 VAPA_1c37730 6be2a3009368f45b63aec0982452649a 224 Gene3D G3DSA:3.30.2350.10 1 213 2.5E-63 T 12-10-2018 VAPA_1c44310 c95ca016c17534144396e6fc6e30b82d 246 Pfam PF00378 Enoyl-CoA hydratase/isomerase 8 243 2.5E-33 T 12-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 VAPA_1c44310 c95ca016c17534144396e6fc6e30b82d 246 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 98 118 - T 12-10-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824 VAPA_1c44310 c95ca016c17534144396e6fc6e30b82d 246 Gene3D G3DSA:3.90.226.10 4 245 2.0E-52 T 12-10-2018 VAPA_1c44310 c95ca016c17534144396e6fc6e30b82d 246 SUPERFAMILY SSF52096 7 244 1.04E-52 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily VAPA_1c07370 213c482b4f54217038b9b45f90a2e5dd 206 SUPERFAMILY SSF50104 150 205 6.88E-19 T 12-10-2018 IPR008991 Translation protein SH3-like domain superfamily VAPA_1c07370 213c482b4f54217038b9b45f90a2e5dd 206 TIGRFAM TIGR00922 nusG: transcription termination/antitermination factor NusG 34 205 7.0E-68 T 12-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 VAPA_1c07370 213c482b4f54217038b9b45f90a2e5dd 206 SMART SM00739 152 179 1.3E-4 T 12-10-2018 IPR005824 KOW VAPA_1c07370 213c482b4f54217038b9b45f90a2e5dd 206 SMART SM00738 31 140 5.5E-44 T 12-10-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 VAPA_1c07370 213c482b4f54217038b9b45f90a2e5dd 206 Pfam PF02357 Transcription termination factor nusG 33 136 3.9E-26 T 12-10-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 VAPA_1c07370 213c482b4f54217038b9b45f90a2e5dd 206 Hamap MF_00948 Transcription termination/antitermination protein NusG [nusG]. 31 206 24.942 T 12-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 VAPA_1c07370 213c482b4f54217038b9b45f90a2e5dd 206 SUPERFAMILY SSF82679 32 143 2.35E-38 T 12-10-2018 IPR036735 NusG, N-terminal domain superfamily GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 VAPA_1c07370 213c482b4f54217038b9b45f90a2e5dd 206 Gene3D G3DSA:2.30.30.30 147 205 3.4E-24 T 12-10-2018 IPR014722 Ribosomal protein L2, domain 2 VAPA_1c07370 213c482b4f54217038b9b45f90a2e5dd 206 Gene3D G3DSA:3.30.70.940 27 146 2.6E-46 T 12-10-2018 IPR036735 NusG, N-terminal domain superfamily GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 VAPA_1c07370 213c482b4f54217038b9b45f90a2e5dd 206 ProSitePatterns PS01014 Transcription termination factor nusG signature. 189 198 - T 12-10-2018 IPR015869 Transcription antitermination protein, NusG, bacteria, conserved site VAPA_1c07370 213c482b4f54217038b9b45f90a2e5dd 206 PRINTS PR00338 Transcription termination factor NUSG signature 86 98 1.4E-19 T 12-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 VAPA_1c07370 213c482b4f54217038b9b45f90a2e5dd 206 PRINTS PR00338 Transcription termination factor NUSG signature 182 198 1.4E-19 T 12-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 VAPA_1c07370 213c482b4f54217038b9b45f90a2e5dd 206 PRINTS PR00338 Transcription termination factor NUSG signature 164 179 1.4E-19 T 12-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 VAPA_1c07370 213c482b4f54217038b9b45f90a2e5dd 206 Pfam PF00467 KOW motif 155 185 3.5E-6 T 12-10-2018 IPR005824 KOW VAPA_2c02670 9f50736710eb540af0f895aec63a0154 164 SUPERFAMILY SSF46785 6 66 5.19E-18 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_2c02670 9f50736710eb540af0f895aec63a0154 164 Pfam PF01037 Lrp/AsnC ligand binding domain 74 146 2.3E-20 T 12-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain VAPA_2c02670 9f50736710eb540af0f895aec63a0154 164 Pfam PF13412 Winged helix-turn-helix DNA-binding 8 53 4.6E-19 T 12-10-2018 VAPA_2c02670 9f50736710eb540af0f895aec63a0154 164 Gene3D G3DSA:3.30.70.920 61 143 5.5E-21 T 12-10-2018 VAPA_2c02670 9f50736710eb540af0f895aec63a0154 164 SMART SM00344 7 116 3.0E-43 T 12-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 VAPA_2c02670 9f50736710eb540af0f895aec63a0154 164 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 7 23 7.4E-17 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 VAPA_2c02670 9f50736710eb540af0f895aec63a0154 164 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 34 53 7.4E-17 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 VAPA_2c02670 9f50736710eb540af0f895aec63a0154 164 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 23 34 7.4E-17 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 VAPA_2c02670 9f50736710eb540af0f895aec63a0154 164 ProSitePatterns PS00519 AsnC-type HTH domain signature. 25 51 - T 12-10-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site VAPA_2c02670 9f50736710eb540af0f895aec63a0154 164 SUPERFAMILY SSF54909 69 154 5.09E-18 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel VAPA_2c02670 9f50736710eb540af0f895aec63a0154 164 Gene3D G3DSA:1.10.10.10 8 58 1.1E-24 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c03740 2005f764b4bcebc9df6426a76bbe0643 286 SMART SM00346 8 99 8.6E-16 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 VAPA_1c03740 2005f764b4bcebc9df6426a76bbe0643 286 Pfam PF09339 IclR helix-turn-helix domain 12 61 7.1E-13 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 VAPA_1c03740 2005f764b4bcebc9df6426a76bbe0643 286 SUPERFAMILY SSF46785 12 80 1.86E-10 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c03740 2005f764b4bcebc9df6426a76bbe0643 286 Gene3D G3DSA:1.10.10.10 8 76 4.8E-15 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c03740 2005f764b4bcebc9df6426a76bbe0643 286 Pfam PF01614 Bacterial transcriptional regulator 146 249 6.5E-16 T 12-10-2018 IPR014757 Transcription regulator IclR, C-terminal VAPA_1c03740 2005f764b4bcebc9df6426a76bbe0643 286 Gene3D G3DSA:3.30.450.40 83 250 1.7E-35 T 12-10-2018 IPR029016 GAF-like domain superfamily VAPA_1c03740 2005f764b4bcebc9df6426a76bbe0643 286 SUPERFAMILY SSF55781 85 251 2.75E-36 T 12-10-2018 VAPA_1c03860 595dc437fe4f90a869c38b85fb8b63b0 124 SUPERFAMILY SSF55159 18 121 2.35E-25 T 12-10-2018 IPR036877 SUI1 domain superfamily GO:0003743|GO:0006413 VAPA_1c03860 595dc437fe4f90a869c38b85fb8b63b0 124 Pfam PF01253 Translation initiation factor SUI1 48 116 1.5E-14 T 12-10-2018 IPR001950 SUI1 domain GO:0003743|GO:0006413 VAPA_1c03860 595dc437fe4f90a869c38b85fb8b63b0 124 PIRSF PIRSF037511 6 124 6.1E-34 T 12-10-2018 IPR005872 Archaeal/bacterial translation initiation factor SUI1 GO:0003743 VAPA_1c03860 595dc437fe4f90a869c38b85fb8b63b0 124 Gene3D G3DSA:3.30.780.10 44 124 1.0E-28 T 12-10-2018 VAPA_1c03860 595dc437fe4f90a869c38b85fb8b63b0 124 TIGRFAM TIGR01158 SUI1_rel: putative translation initiation factor SUI1 19 124 8.2E-34 T 12-10-2018 IPR005872 Archaeal/bacterial translation initiation factor SUI1 GO:0003743 VAPA_1c31680 3c2731761ee1c9d8b7eb5ad1c2c9ebd2 414 Gene3D G3DSA:3.40.640.10 37 286 1.5E-184 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 VAPA_1c31680 3c2731761ee1c9d8b7eb5ad1c2c9ebd2 414 Pfam PF00464 Serine hydroxymethyltransferase 8 382 2.2E-170 T 12-10-2018 IPR039429 Serine hydroxymethyltransferase-like domain KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 VAPA_1c31680 3c2731761ee1c9d8b7eb5ad1c2c9ebd2 414 ProSitePatterns PS00096 Serine hydroxymethyltransferase pyridoxal-phosphate attachment site. 221 237 - T 12-10-2018 IPR019798 Serine hydroxymethyltransferase, pyridoxal phosphate binding site GO:0030170 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 VAPA_1c31680 3c2731761ee1c9d8b7eb5ad1c2c9ebd2 414 Gene3D G3DSA:3.90.1150.10 10 391 1.5E-184 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 VAPA_1c31680 3c2731761ee1c9d8b7eb5ad1c2c9ebd2 414 PIRSF PIRSF000412 1 414 1.2E-163 T 12-10-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0019264|GO:0030170|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 VAPA_1c31680 3c2731761ee1c9d8b7eb5ad1c2c9ebd2 414 SUPERFAMILY SSF53383 7 413 2.78E-174 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase VAPA_1c31680 3c2731761ee1c9d8b7eb5ad1c2c9ebd2 414 Hamap MF_00051 Serine hydroxymethyltransferase [glyA]. 7 414 51.697 T 12-10-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0019264|GO:0030170|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 VAPA_1c07540 9c10ddb09a66f55bb90b5bea9be81cc2 433 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 187 343 2.6E-54 T 12-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 VAPA_1c07540 9c10ddb09a66f55bb90b5bea9be81cc2 433 SMART SM00283 128 375 9.8E-93 T 12-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 VAPA_1c07540 9c10ddb09a66f55bb90b5bea9be81cc2 433 Gene3D G3DSA:1.10.287.950 74 377 7.4E-92 T 12-10-2018 VAPA_1c07540 9c10ddb09a66f55bb90b5bea9be81cc2 433 SUPERFAMILY SSF58104 95 376 7.98E-76 T 12-10-2018 VAPA_1c37590 d14938105353ac4f0c2638d6c9d4f59f 397 Gene3D G3DSA:3.40.50.300 2 230 8.8E-72 T 12-10-2018 VAPA_1c37590 d14938105353ac4f0c2638d6c9d4f59f 397 SMART SM00833 257 372 1.1E-50 T 12-10-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal VAPA_1c37590 d14938105353ac4f0c2638d6c9d4f59f 397 Pfam PF07683 Cobalamin synthesis protein cobW C-terminal domain 257 372 2.7E-29 T 12-10-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal VAPA_1c37590 d14938105353ac4f0c2638d6c9d4f59f 397 SUPERFAMILY SSF52540 3 323 4.6E-47 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c37590 d14938105353ac4f0c2638d6c9d4f59f 397 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 6 210 3.1E-58 T 12-10-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain VAPA_1c52510 2e8c3f67b2351c72c98663a7edcdd91d 110 Gene3D G3DSA:2.30.30.30 1 108 2.5E-30 T 12-10-2018 IPR014722 Ribosomal protein L2, domain 2 VAPA_1c52510 2e8c3f67b2351c72c98663a7edcdd91d 110 SUPERFAMILY SSF50104 3 104 1.15E-25 T 12-10-2018 IPR008991 Translation protein SH3-like domain superfamily VAPA_1c52510 2e8c3f67b2351c72c98663a7edcdd91d 110 Hamap MF_01326_B 50S ribosomal protein L24 [rplX]. 2 101 17.926 T 12-10-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 VAPA_1c52510 2e8c3f67b2351c72c98663a7edcdd91d 110 SMART SM00739 3 30 5.2E-4 T 12-10-2018 IPR005824 KOW VAPA_1c52510 2e8c3f67b2351c72c98663a7edcdd91d 110 Pfam PF17136 Ribosomal proteins 50S L24/mitochondrial 39S L24 38 107 2.3E-22 T 12-10-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 VAPA_1c52510 2e8c3f67b2351c72c98663a7edcdd91d 110 TIGRFAM TIGR01079 rplX_bact: ribosomal protein uL24 1 107 6.4E-30 T 12-10-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 VAPA_1c52510 2e8c3f67b2351c72c98663a7edcdd91d 110 ProSitePatterns PS01108 Ribosomal protein L24 signature. 7 24 - T 12-10-2018 IPR005825 Ribosomal protein L24/L26, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 VAPA_1c52510 2e8c3f67b2351c72c98663a7edcdd91d 110 Pfam PF00467 KOW motif 6 25 7.9E-5 T 12-10-2018 IPR005824 KOW VAPA_2c06350 bd81d076cb1d5eb2c6408630ff09dccd 343 Pfam PF01312 FlhB HrpN YscU SpaS Family 3 338 6.5E-86 T 12-10-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 VAPA_2c06350 bd81d076cb1d5eb2c6408630ff09dccd 343 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 202 220 6.3E-20 T 12-10-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 VAPA_2c06350 bd81d076cb1d5eb2c6408630ff09dccd 343 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 222 239 6.3E-20 T 12-10-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 VAPA_2c06350 bd81d076cb1d5eb2c6408630ff09dccd 343 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 294 315 6.3E-20 T 12-10-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 VAPA_2c06350 bd81d076cb1d5eb2c6408630ff09dccd 343 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 5 27 6.3E-20 T 12-10-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 VAPA_2c06350 bd81d076cb1d5eb2c6408630ff09dccd 343 SUPERFAMILY SSF160544 238 340 2.88E-18 T 12-10-2018 IPR029025 Type III secretion system substrate exporter, C-terminal VAPA_2c06350 bd81d076cb1d5eb2c6408630ff09dccd 343 Gene3D G3DSA:3.40.1690.10 211 342 4.7E-31 T 12-10-2018 IPR029025 Type III secretion system substrate exporter, C-terminal VAPA_1c28460 e6db5786b6aaf85ff247b572b7736997 293 Gene3D G3DSA:1.10.8.10 3 93 3.5E-5 T 12-10-2018 VAPA_1c28460 e6db5786b6aaf85ff247b572b7736997 293 Gene3D G3DSA:3.40.50.150 94 289 2.2E-39 T 12-10-2018 VAPA_1c28460 e6db5786b6aaf85ff247b572b7736997 293 TIGRFAM TIGR00536 hemK_fam: methyltransferase, HemK family 21 286 8.1E-55 T 12-10-2018 IPR004556 Modification methylase HemK GO:0006479|GO:0008276 VAPA_1c28460 e6db5786b6aaf85ff247b572b7736997 293 SUPERFAMILY SSF53335 4 255 8.59E-40 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase VAPA_1c28460 e6db5786b6aaf85ff247b572b7736997 293 Pfam PF05175 Methyltransferase small domain 121 203 1.7E-16 T 12-10-2018 IPR007848 Methyltransferase small domain GO:0008168 VAPA_1c28460 e6db5786b6aaf85ff247b572b7736997 293 PIRSF PIRSF037167 1 292 1.6E-100 T 12-10-2018 IPR017127 Ribosomal protein L3-specific, glutamine-N5-methyltransferase GO:0005622|GO:0009007|GO:0032775 VAPA_1c28460 e6db5786b6aaf85ff247b572b7736997 293 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 192 198 - T 12-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 VAPA_1c28460 e6db5786b6aaf85ff247b572b7736997 293 TIGRFAM TIGR03533 L3_gln_methyl: protein-(glutamine-N5) methyltransferase, ribosomal protein L3-specific 1 283 1.8E-99 T 12-10-2018 IPR017127 Ribosomal protein L3-specific, glutamine-N5-methyltransferase GO:0005622|GO:0009007|GO:0032775 VAPA_2c06690 192a0a1b0734f8e3a79c7f70f17057a6 237 SUPERFAMILY SSF48008 93 228 2.46E-26 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal VAPA_2c06690 192a0a1b0734f8e3a79c7f70f17057a6 237 SMART SM00345 17 76 2.3E-22 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_2c06690 192a0a1b0734f8e3a79c7f70f17057a6 237 Pfam PF07729 FCD domain 96 221 3.0E-26 T 12-10-2018 IPR011711 GntR, C-terminal VAPA_2c06690 192a0a1b0734f8e3a79c7f70f17057a6 237 SUPERFAMILY SSF46785 7 80 9.08E-23 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_2c06690 192a0a1b0734f8e3a79c7f70f17057a6 237 Gene3D G3DSA:1.20.120.530 95 232 8.6E-29 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal VAPA_2c06690 192a0a1b0734f8e3a79c7f70f17057a6 237 Pfam PF00392 Bacterial regulatory proteins, gntR family 13 76 1.0E-20 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_2c06690 192a0a1b0734f8e3a79c7f70f17057a6 237 Gene3D G3DSA:1.10.10.10 7 83 4.3E-23 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_2c06690 192a0a1b0734f8e3a79c7f70f17057a6 237 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 36 50 1.0E-8 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_2c06690 192a0a1b0734f8e3a79c7f70f17057a6 237 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 50 66 1.0E-8 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_2c06690 192a0a1b0734f8e3a79c7f70f17057a6 237 SMART SM00895 96 222 4.1E-22 T 12-10-2018 IPR011711 GntR, C-terminal VAPA_1c21480 88933cbb45072b80459544c46d55fc75 393 Gene3D G3DSA:3.40.50.10540 4 387 2.4E-119 T 12-10-2018 IPR023606 CoA-transferase family III domain superfamily VAPA_1c21480 88933cbb45072b80459544c46d55fc75 393 Pfam PF02515 CoA-transferase family III 5 370 7.6E-109 T 12-10-2018 IPR003673 CoA-transferase family III GO:0003824 VAPA_1c21480 88933cbb45072b80459544c46d55fc75 393 SUPERFAMILY SSF89796 1 393 1.16E-125 T 12-10-2018 IPR023606 CoA-transferase family III domain superfamily VAPA_1c21480 88933cbb45072b80459544c46d55fc75 393 Gene3D G3DSA:3.30.1540.10 230 323 2.4E-119 T 12-10-2018 VAPA_1c32630 b06757c43c41cefa5535d44e1ebfccb3 874 Gene3D G3DSA:3.30.930.10 6 253 1.9E-115 T 12-10-2018 VAPA_1c32630 b06757c43c41cefa5535d44e1ebfccb3 874 SUPERFAMILY SSF55186 552 707 7.06E-50 T 12-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 VAPA_1c32630 b06757c43c41cefa5535d44e1ebfccb3 874 Gene3D G3DSA:3.30.54.20 624 676 4.9E-49 T 12-10-2018 VAPA_1c32630 b06757c43c41cefa5535d44e1ebfccb3 874 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 653 695 1.7E-16 T 12-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 VAPA_1c32630 b06757c43c41cefa5535d44e1ebfccb3 874 Pfam PF01411 tRNA synthetases class II (A) 10 555 6.2E-212 T 12-10-2018 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 VAPA_1c32630 b06757c43c41cefa5535d44e1ebfccb3 874 TIGRFAM TIGR00344 alaS: alanine--tRNA ligase 10 853 1.3E-299 T 12-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 VAPA_1c32630 b06757c43c41cefa5535d44e1ebfccb3 874 SMART SM00863 653 695 1.5E-19 T 12-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 VAPA_1c32630 b06757c43c41cefa5535d44e1ebfccb3 874 SUPERFAMILY SSF50447 456 552 4.59E-17 T 12-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily VAPA_1c32630 b06757c43c41cefa5535d44e1ebfccb3 874 Pfam PF02272 DHHA1 domain 733 870 5.4E-26 T 12-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 VAPA_1c32630 b06757c43c41cefa5535d44e1ebfccb3 874 Hamap MF_00036_B Alanine--tRNA ligase [alaS]. 1 874 195.337 T 12-10-2018 IPR023033 Alanine-tRNA ligase, eukaryota/bacteria GO:0004813 KEGG: 00970+6.1.1.7 VAPA_1c32630 b06757c43c41cefa5535d44e1ebfccb3 874 Gene3D G3DSA:3.10.310.40 763 871 9.3E-28 T 12-10-2018 VAPA_1c32630 b06757c43c41cefa5535d44e1ebfccb3 874 Gene3D G3DSA:2.40.30.130 460 552 1.9E-11 T 12-10-2018 VAPA_1c32630 b06757c43c41cefa5535d44e1ebfccb3 874 SUPERFAMILY SSF101353 257 446 4.71E-58 T 12-10-2018 IPR018162 Alanine-tRNA ligase, class IIc, anti-codon-binding domain superfamily GO:0000166|GO:0004813|GO:0005524|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7 VAPA_1c32630 b06757c43c41cefa5535d44e1ebfccb3 874 Gene3D G3DSA:3.30.980.10 562 696 4.9E-49 T 12-10-2018 VAPA_1c32630 b06757c43c41cefa5535d44e1ebfccb3 874 SUPERFAMILY SSF55681 6 256 4.22E-105 T 12-10-2018 VAPA_1c32630 b06757c43c41cefa5535d44e1ebfccb3 874 PRINTS PR00980 Alanyl-tRNA synthetase signature 79 90 4.6E-31 T 12-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 VAPA_1c32630 b06757c43c41cefa5535d44e1ebfccb3 874 PRINTS PR00980 Alanyl-tRNA synthetase signature 210 221 4.6E-31 T 12-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 VAPA_1c32630 b06757c43c41cefa5535d44e1ebfccb3 874 PRINTS PR00980 Alanyl-tRNA synthetase signature 237 250 4.6E-31 T 12-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 VAPA_1c32630 b06757c43c41cefa5535d44e1ebfccb3 874 PRINTS PR00980 Alanyl-tRNA synthetase signature 283 299 4.6E-31 T 12-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 VAPA_1c32630 b06757c43c41cefa5535d44e1ebfccb3 874 PRINTS PR00980 Alanyl-tRNA synthetase signature 307 320 4.6E-31 T 12-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 VAPA_1c27810 2757c620a28944bf272cc1d7a4af4455 322 SUPERFAMILY SSF53850 113 281 8.41E-9 T 12-10-2018 VAPA_1c27810 2757c620a28944bf272cc1d7a4af4455 322 Gene3D G3DSA:3.40.190.150 28 312 1.9E-106 T 12-10-2018 VAPA_1c27810 2757c620a28944bf272cc1d7a4af4455 322 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 48 319 2.3E-85 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c27810 2757c620a28944bf272cc1d7a4af4455 322 PIRSF PIRSF017082 1 322 2.4E-74 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c27810 2757c620a28944bf272cc1d7a4af4455 322 Gene3D G3DSA:3.40.190.10 125 248 1.9E-106 T 12-10-2018 VAPA_1c34270 c81244ae1bcc1d03c05e993636299576 277 Gene3D G3DSA:3.40.50.720 108 247 2.9E-66 T 12-10-2018 VAPA_1c34270 c81244ae1bcc1d03c05e993636299576 277 Pfam PF00899 ThiF family 123 159 8.9E-7 T 12-10-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 VAPA_1c34270 c81244ae1bcc1d03c05e993636299576 277 Gene3D G3DSA:3.40.50.10860 6 107 2.9E-66 T 12-10-2018 VAPA_1c34270 c81244ae1bcc1d03c05e993636299576 277 SUPERFAMILY SSF51735 108 251 9.85E-29 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c34270 c81244ae1bcc1d03c05e993636299576 277 Pfam PF08501 Shikimate dehydrogenase substrate binding domain 13 94 1.7E-15 T 12-10-2018 IPR013708 Shikimate dehydrogenase substrate binding, N-terminal GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 VAPA_1c34270 c81244ae1bcc1d03c05e993636299576 277 SUPERFAMILY SSF53223 1 105 2.99E-24 T 12-10-2018 VAPA_1c05880 72abea2bd07674e697c1a9c0423432fc 323 Pfam PF04392 ABC transporter substrate binding protein 127 312 3.1E-10 T 12-10-2018 IPR007487 ABC transporter, substrate-binding protein VAPA_1c05880 72abea2bd07674e697c1a9c0423432fc 323 Gene3D G3DSA:3.40.50.2300 142 281 9.2E-18 T 12-10-2018 VAPA_1c32120 81166d51f0f1c994b3e4ba17ac94420a 327 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 119 295 3.8E-47 T 12-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 VAPA_1c32120 81166d51f0f1c994b3e4ba17ac94420a 327 SUPERFAMILY SSF52283 64 133 2.14E-5 T 12-10-2018 VAPA_1c32120 81166d51f0f1c994b3e4ba17ac94420a 327 Gene3D G3DSA:3.40.50.720 55 324 4.5E-79 T 12-10-2018 VAPA_1c32120 81166d51f0f1c994b3e4ba17ac94420a 327 Gene3D G3DSA:3.40.50.720 110 301 4.5E-79 T 12-10-2018 VAPA_1c32120 81166d51f0f1c994b3e4ba17ac94420a 327 SUPERFAMILY SSF51735 112 295 8.17E-46 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c43400 7a937e01cf93ca1e5ac3d606a320702a 516 Pfam PF12729 Four helix bundle sensory module for signal transduction 6 173 1.4E-9 T 12-10-2018 IPR024478 Chemotaxis methyl-accepting receptor HlyB-like, 4HB MCP domain VAPA_1c43400 7a937e01cf93ca1e5ac3d606a320702a 516 Gene3D G3DSA:1.10.287.950 212 514 3.7E-94 T 12-10-2018 VAPA_1c43400 7a937e01cf93ca1e5ac3d606a320702a 516 SMART SM00304 213 265 2.7E-10 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 VAPA_1c43400 7a937e01cf93ca1e5ac3d606a320702a 516 SMART SM00283 266 513 1.1E-90 T 12-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 VAPA_1c43400 7a937e01cf93ca1e5ac3d606a320702a 516 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 325 481 1.5E-55 T 12-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 VAPA_1c43400 7a937e01cf93ca1e5ac3d606a320702a 516 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 287 316 6.4E-61 T 12-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 VAPA_1c43400 7a937e01cf93ca1e5ac3d606a320702a 516 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 364 391 6.4E-61 T 12-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 VAPA_1c43400 7a937e01cf93ca1e5ac3d606a320702a 516 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 7 32 6.4E-61 T 12-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 VAPA_1c43400 7a937e01cf93ca1e5ac3d606a320702a 516 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 393 422 6.4E-61 T 12-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 VAPA_1c43400 7a937e01cf93ca1e5ac3d606a320702a 516 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 441 470 6.4E-61 T 12-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 VAPA_1c43400 7a937e01cf93ca1e5ac3d606a320702a 516 SUPERFAMILY SSF58104 233 514 2.62E-77 T 12-10-2018 VAPA_1c43400 7a937e01cf93ca1e5ac3d606a320702a 516 Pfam PF00672 HAMP domain 213 256 1.2E-9 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 VAPA_1c19600 0fc4a10613703746f4d57dfb4d91b78e 259 SMART SM00342 163 245 1.8E-25 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 VAPA_1c19600 0fc4a10613703746f4d57dfb4d91b78e 259 Gene3D G3DSA:1.10.10.60 148 249 2.6E-20 T 12-10-2018 VAPA_1c19600 0fc4a10613703746f4d57dfb4d91b78e 259 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 229 245 8.3E-6 T 12-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 VAPA_1c19600 0fc4a10613703746f4d57dfb4d91b78e 259 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 214 229 8.3E-6 T 12-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 VAPA_1c19600 0fc4a10613703746f4d57dfb4d91b78e 259 SUPERFAMILY SSF51182 16 172 2.76E-8 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily VAPA_1c19600 0fc4a10613703746f4d57dfb4d91b78e 259 SUPERFAMILY SSF46689 200 247 1.75E-8 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 VAPA_1c19600 0fc4a10613703746f4d57dfb4d91b78e 259 Pfam PF12833 Helix-turn-helix domain 169 245 1.0E-20 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 VAPA_1c19600 0fc4a10613703746f4d57dfb4d91b78e 259 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 200 241 - T 12-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 VAPA_1c54840 821c18ea52c75a716cff45bd4b93f0a9 255 Hamap MF_00607 Ribosomal RNA small subunit methyltransferase A [rsmA]. 3 252 53.845 T 12-10-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 VAPA_1c54840 821c18ea52c75a716cff45bd4b93f0a9 255 Gene3D G3DSA:1.10.8.100 191 254 2.3E-21 T 12-10-2018 IPR023165 rRNA adenine dimethylase-like Reactome: R-HSA-2151201|Reactome: R-HSA-6793080 VAPA_1c54840 821c18ea52c75a716cff45bd4b93f0a9 255 Gene3D G3DSA:3.40.50.150 1 188 1.2E-60 T 12-10-2018 VAPA_1c54840 821c18ea52c75a716cff45bd4b93f0a9 255 SUPERFAMILY SSF53335 11 251 4.05E-66 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase VAPA_1c54840 821c18ea52c75a716cff45bd4b93f0a9 255 TIGRFAM TIGR00755 ksgA: ribosomal RNA small subunit methyltransferase A 5 250 1.0E-74 T 12-10-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 VAPA_1c54840 821c18ea52c75a716cff45bd4b93f0a9 255 ProSitePatterns PS01131 Ribosomal RNA adenine dimethylases signature. 35 62 - T 12-10-2018 IPR020596 Ribosomal RNA adenine methylase transferase, conserved site GO:0000154|GO:0000179|GO:0008649 VAPA_1c54840 821c18ea52c75a716cff45bd4b93f0a9 255 SMART SM00650 19 188 2.5E-74 T 12-10-2018 IPR020598 Ribosomal RNA adenine methylase transferase, N-terminal GO:0000154|GO:0000179|GO:0008649 VAPA_1c54840 821c18ea52c75a716cff45bd4b93f0a9 255 Pfam PF00398 Ribosomal RNA adenine dimethylase 5 221 1.4E-56 T 12-10-2018 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm VAPA_1c51460 2411fedfd56e29788ab3fd1e64b69070 336 PIRSF PIRSF017082 7 334 4.3E-65 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c51460 2411fedfd56e29788ab3fd1e64b69070 336 Gene3D G3DSA:3.40.190.10 141 262 2.2E-51 T 12-10-2018 VAPA_1c51460 2411fedfd56e29788ab3fd1e64b69070 336 Gene3D G3DSA:3.40.190.150 48 323 2.2E-51 T 12-10-2018 VAPA_1c51460 2411fedfd56e29788ab3fd1e64b69070 336 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 77 330 4.5E-19 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c51460 2411fedfd56e29788ab3fd1e64b69070 336 SUPERFAMILY SSF53850 120 290 7.67E-9 T 12-10-2018 VAPA_1c40560 2b35897f0108878fe1d524bb22aed4e4 471 Pfam PF02913 FAD linked oxidases, C-terminal domain 228 470 5.8E-45 T 12-10-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 VAPA_1c40560 2b35897f0108878fe1d524bb22aed4e4 471 Gene3D G3DSA:3.30.465.10 102 222 3.3E-44 T 12-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 VAPA_1c40560 2b35897f0108878fe1d524bb22aed4e4 471 Gene3D G3DSA:3.30.43.10 7 99 4.5E-18 T 12-10-2018 IPR016167 FAD-binding, type PCMH, subdomain 1 VAPA_1c40560 2b35897f0108878fe1d524bb22aed4e4 471 Gene3D G3DSA:3.30.70.2740 347 430 2.7E-19 T 12-10-2018 VAPA_1c40560 2b35897f0108878fe1d524bb22aed4e4 471 Pfam PF01565 FAD binding domain 47 184 2.9E-33 T 12-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 VAPA_1c40560 2b35897f0108878fe1d524bb22aed4e4 471 Gene3D G3DSA:1.10.45.10 431 471 1.4E-15 T 12-10-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 VAPA_1c40560 2b35897f0108878fe1d524bb22aed4e4 471 Gene3D G3DSA:3.30.70.2190 223 342 2.3E-28 T 12-10-2018 VAPA_1c40560 2b35897f0108878fe1d524bb22aed4e4 471 SUPERFAMILY SSF56176 15 223 4.16E-68 T 12-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 VAPA_1c40560 2b35897f0108878fe1d524bb22aed4e4 471 SUPERFAMILY SSF55103 226 471 1.34E-50 T 12-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 VAPA_2c04460 48f4b76b90230ae9637933ba22820a9a 220 Gene3D G3DSA:3.40.109.10 26 191 1.1E-39 T 12-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 VAPA_2c04460 48f4b76b90230ae9637933ba22820a9a 220 SUPERFAMILY SSF55469 21 207 6.54E-33 T 12-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 VAPA_2c04460 48f4b76b90230ae9637933ba22820a9a 220 Pfam PF00881 Nitroreductase family 33 189 1.7E-27 T 12-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 VAPA_2c04460 48f4b76b90230ae9637933ba22820a9a 220 PIRSF PIRSF000232 21 212 2.9E-56 T 12-10-2018 IPR026021 Putative NAD(P)H nitroreductase YdjA-like VAPA_1c07720 95379992a96f851790875f4b56dd898a 801 SUPERFAMILY SSF55073 626 780 5.41E-48 T 12-10-2018 IPR029787 Nucleotide cyclase VAPA_1c07720 95379992a96f851790875f4b56dd898a 801 Pfam PF08448 PAS fold 505 611 1.0E-15 T 12-10-2018 IPR013656 PAS fold-4 VAPA_1c07720 95379992a96f851790875f4b56dd898a 801 Pfam PF08448 PAS fold 381 488 1.3E-14 T 12-10-2018 IPR013656 PAS fold-4 VAPA_1c07720 95379992a96f851790875f4b56dd898a 801 SUPERFAMILY SSF55785 483 608 1.56E-15 T 12-10-2018 IPR035965 PAS domain superfamily VAPA_1c07720 95379992a96f851790875f4b56dd898a 801 SMART SM00267 610 781 3.8E-61 T 12-10-2018 IPR000160 GGDEF domain VAPA_1c07720 95379992a96f851790875f4b56dd898a 801 Gene3D G3DSA:3.30.450.20 359 495 1.9E-18 T 12-10-2018 VAPA_1c07720 95379992a96f851790875f4b56dd898a 801 Pfam PF00990 Diguanylate cyclase, GGDEF domain 623 777 3.5E-48 T 12-10-2018 IPR000160 GGDEF domain VAPA_1c07720 95379992a96f851790875f4b56dd898a 801 SMART SM00091 374 440 0.016 T 12-10-2018 IPR000014 PAS domain VAPA_1c07720 95379992a96f851790875f4b56dd898a 801 SMART SM00091 498 564 4.3E-4 T 12-10-2018 IPR000014 PAS domain VAPA_1c07720 95379992a96f851790875f4b56dd898a 801 Gene3D G3DSA:3.30.70.270 619 783 2.8E-56 T 12-10-2018 VAPA_1c07720 95379992a96f851790875f4b56dd898a 801 Gene3D G3DSA:3.30.450.20 160 295 2.9E-18 T 12-10-2018 VAPA_1c07720 95379992a96f851790875f4b56dd898a 801 Gene3D G3DSA:3.30.450.20 496 618 4.7E-19 T 12-10-2018 VAPA_1c07720 95379992a96f851790875f4b56dd898a 801 Pfam PF02743 Cache domain 56 275 1.5E-20 T 12-10-2018 IPR033479 Double Cache domain 1 VAPA_1c07720 95379992a96f851790875f4b56dd898a 801 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 618 781 9.8E-47 T 12-10-2018 IPR000160 GGDEF domain VAPA_1c07720 95379992a96f851790875f4b56dd898a 801 SUPERFAMILY SSF55785 361 484 7.42E-15 T 12-10-2018 IPR035965 PAS domain superfamily VAPA_1c07720 95379992a96f851790875f4b56dd898a 801 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 371 490 5.1E-8 T 12-10-2018 IPR000014 PAS domain VAPA_1c07720 95379992a96f851790875f4b56dd898a 801 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 496 616 7.3E-6 T 12-10-2018 IPR000014 PAS domain VAPA_1c30320 1a48463439c64b24d9edf24c1c5c97cc 417 Gene3D G3DSA:3.10.580.10 286 397 3.7E-5 T 12-10-2018 VAPA_1c30320 1a48463439c64b24d9edf24c1c5c97cc 417 SUPERFAMILY SSF54631 275 394 5.5E-10 T 12-10-2018 VAPA_1c30320 1a48463439c64b24d9edf24c1c5c97cc 417 ProSitePatterns PS00211 ABC transporters family signature. 165 179 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_1c30320 1a48463439c64b24d9edf24c1c5c97cc 417 SUPERFAMILY SSF52540 43 269 1.89E-74 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c30320 1a48463439c64b24d9edf24c1c5c97cc 417 Gene3D G3DSA:3.40.50.300 38 276 4.9E-72 T 12-10-2018 VAPA_1c30320 1a48463439c64b24d9edf24c1c5c97cc 417 TIGRFAM TIGR01186 proV: glycine betaine/L-proline transport ATP binding subunit 37 395 3.5E-140 T 12-10-2018 IPR005892 Glycine betaine transport ATP-binding subunit GO:0005524|GO:0016020|GO:0031460 VAPA_1c30320 1a48463439c64b24d9edf24c1c5c97cc 417 Pfam PF00005 ABC transporter 46 192 8.5E-34 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c30320 1a48463439c64b24d9edf24c1c5c97cc 417 SMART SM00382 53 250 3.6E-19 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c36140 a06f2dfee3d2b8c7ba1f81e99a3988cc 182 PIRSF PIRSF000216 1 181 3.2E-56 T 12-10-2018 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VAPA_1c36140 a06f2dfee3d2b8c7ba1f81e99a3988cc 182 Gene3D G3DSA:3.40.30.10 91 182 1.7E-24 T 12-10-2018 VAPA_1c36140 a06f2dfee3d2b8c7ba1f81e99a3988cc 182 Pfam PF01257 Thioredoxin-like [2Fe-2S] ferredoxin 30 173 1.7E-47 T 12-10-2018 VAPA_1c36140 a06f2dfee3d2b8c7ba1f81e99a3988cc 182 TIGRFAM TIGR01958 nuoE_fam: NADH-quinone oxidoreductase, E subunit 29 173 1.3E-53 T 12-10-2018 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VAPA_1c36140 a06f2dfee3d2b8c7ba1f81e99a3988cc 182 Gene3D G3DSA:1.10.10.1590 21 90 5.8E-21 T 12-10-2018 VAPA_1c36140 a06f2dfee3d2b8c7ba1f81e99a3988cc 182 SUPERFAMILY SSF52833 20 176 1.9E-47 T 12-10-2018 IPR036249 Thioredoxin-like superfamily VAPA_1c49430 c084a4ee6fc99538c547caae15b3ead5 137 SUPERFAMILY SSF54593 1 128 2.55E-26 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase VAPA_1c49430 c084a4ee6fc99538c547caae15b3ead5 137 Gene3D G3DSA:3.10.180.10 1 132 2.6E-40 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase VAPA_1c49430 c084a4ee6fc99538c547caae15b3ead5 137 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 4 125 1.3E-6 T 12-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain VAPA_1c49590 4651037923b283928e142c33837f4414 537 Pfam PF13193 AMP-binding enzyme C-terminal domain 452 527 1.6E-20 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain VAPA_1c49590 4651037923b283928e142c33837f4414 537 SUPERFAMILY SSF56801 4 535 4.45E-146 T 12-10-2018 VAPA_1c49590 4651037923b283928e142c33837f4414 537 Gene3D G3DSA:3.30.300.30 439 537 3.1E-30 T 12-10-2018 VAPA_1c49590 4651037923b283928e142c33837f4414 537 Pfam PF00501 AMP-binding enzyme 17 444 2.4E-98 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 VAPA_1c49590 4651037923b283928e142c33837f4414 537 ProSitePatterns PS00455 Putative AMP-binding domain signature. 194 205 - T 12-10-2018 IPR020845 AMP-binding, conserved site VAPA_1c49590 4651037923b283928e142c33837f4414 537 Gene3D G3DSA:3.40.50.12780 3 438 1.7E-110 T 12-10-2018 VAPA_1c24550 db945b7f5966a50ad50a805d31bd6cce 233 TIGRFAM TIGR02135 phoU_full: phosphate transport system regulatory protein PhoU 8 219 1.1E-64 T 12-10-2018 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 VAPA_1c24550 db945b7f5966a50ad50a805d31bd6cce 233 PIRSF PIRSF003107 3 225 9.3E-58 T 12-10-2018 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 VAPA_1c24550 db945b7f5966a50ad50a805d31bd6cce 233 SUPERFAMILY SSF109755 8 229 5.65E-65 T 12-10-2018 VAPA_1c24550 db945b7f5966a50ad50a805d31bd6cce 233 Gene3D G3DSA:1.20.58.220 119 232 8.4E-31 T 12-10-2018 IPR038078 PhoU-like domain superfamily VAPA_1c24550 db945b7f5966a50ad50a805d31bd6cce 233 Pfam PF01895 PhoU domain 22 108 2.7E-17 T 12-10-2018 IPR026022 PhoU domain VAPA_1c24550 db945b7f5966a50ad50a805d31bd6cce 233 Pfam PF01895 PhoU domain 129 210 8.6E-16 T 12-10-2018 IPR026022 PhoU domain VAPA_1c24550 db945b7f5966a50ad50a805d31bd6cce 233 Gene3D G3DSA:1.20.58.220 1 118 2.4E-36 T 12-10-2018 IPR038078 PhoU-like domain superfamily VAPA_1c26420 b128f345ad5c0f5f2dd35366f4203c13 242 Pfam PF02525 Flavodoxin-like fold 7 219 2.3E-37 T 12-10-2018 IPR003680 Flavodoxin-like fold VAPA_1c26420 b128f345ad5c0f5f2dd35366f4203c13 242 Gene3D G3DSA:3.40.50.360 4 224 5.8E-51 T 12-10-2018 IPR029039 Flavoprotein-like superfamily VAPA_1c26420 b128f345ad5c0f5f2dd35366f4203c13 242 Hamap MF_01216 FMN-dependent NADH-azoreductase [azoR]. 6 221 26.192 T 12-10-2018 IPR023048 NADH-azoreductase, FMN-dependent GO:0016661|GO:0055114 VAPA_1c26420 b128f345ad5c0f5f2dd35366f4203c13 242 SUPERFAMILY SSF52218 7 226 2.79E-43 T 12-10-2018 IPR029039 Flavoprotein-like superfamily VAPA_1c00740 4f5cfc8299e6a74725de148e545bdaf0 415 SUPERFAMILY SSF51556 59 367 1.15E-89 T 12-10-2018 IPR032466 Metal-dependent hydrolase VAPA_1c00740 4f5cfc8299e6a74725de148e545bdaf0 415 SUPERFAMILY SSF51338 348 415 1.46E-14 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 VAPA_1c00740 4f5cfc8299e6a74725de148e545bdaf0 415 Pfam PF01979 Amidohydrolase family 55 394 1.6E-43 T 12-10-2018 IPR006680 Amidohydrolase-related GO:0016787 VAPA_1c00740 4f5cfc8299e6a74725de148e545bdaf0 415 Gene3D G3DSA:2.30.40.10 9 408 1.5E-159 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 VAPA_1c00740 4f5cfc8299e6a74725de148e545bdaf0 415 Gene3D G3DSA:3.20.20.140 60 365 1.5E-159 T 12-10-2018 VAPA_1c00740 4f5cfc8299e6a74725de148e545bdaf0 415 SUPERFAMILY SSF51338 4 58 7.73E-18 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 VAPA_1c38500 caaeb44ccdd1ad7aa4cefb080a625e00 460 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 166 185 3.8E-26 T 12-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 VAPA_1c38500 caaeb44ccdd1ad7aa4cefb080a625e00 460 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 200 213 3.8E-26 T 12-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 VAPA_1c38500 caaeb44ccdd1ad7aa4cefb080a625e00 460 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 229 244 3.8E-26 T 12-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 VAPA_1c38500 caaeb44ccdd1ad7aa4cefb080a625e00 460 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 94 108 3.8E-26 T 12-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 VAPA_1c38500 caaeb44ccdd1ad7aa4cefb080a625e00 460 SUPERFAMILY SSF55957 362 450 2.62E-20 T 12-10-2018 IPR036900 Alpha-D-phosphohexomutase, C-terminal domain superfamily GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 VAPA_1c38500 caaeb44ccdd1ad7aa4cefb080a625e00 460 Gene3D G3DSA:3.30.310.50 364 456 6.2E-25 T 12-10-2018 VAPA_1c38500 caaeb44ccdd1ad7aa4cefb080a625e00 460 Gene3D G3DSA:3.40.120.10 168 245 1.1E-32 T 12-10-2018 VAPA_1c38500 caaeb44ccdd1ad7aa4cefb080a625e00 460 SUPERFAMILY SSF53738 254 351 2.67E-30 T 12-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 VAPA_1c38500 caaeb44ccdd1ad7aa4cefb080a625e00 460 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 152 249 9.7E-26 T 12-10-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 VAPA_1c38500 caaeb44ccdd1ad7aa4cefb080a625e00 460 SUPERFAMILY SSF53738 6 127 6.28E-37 T 12-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 VAPA_1c38500 caaeb44ccdd1ad7aa4cefb080a625e00 460 Gene3D G3DSA:3.40.120.10 1 148 4.8E-50 T 12-10-2018 VAPA_1c38500 caaeb44ccdd1ad7aa4cefb080a625e00 460 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 368 446 2.0E-13 T 12-10-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 VAPA_1c38500 caaeb44ccdd1ad7aa4cefb080a625e00 460 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 254 362 3.4E-20 T 12-10-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 VAPA_1c38500 caaeb44ccdd1ad7aa4cefb080a625e00 460 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 7 135 2.5E-34 T 12-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 VAPA_1c38500 caaeb44ccdd1ad7aa4cefb080a625e00 460 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 95 104 - T 12-10-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 VAPA_1c38500 caaeb44ccdd1ad7aa4cefb080a625e00 460 SUPERFAMILY SSF53738 150 250 4.32E-30 T 12-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 VAPA_1c38500 caaeb44ccdd1ad7aa4cefb080a625e00 460 Gene3D G3DSA:3.40.120.10 246 363 7.4E-39 T 12-10-2018 VAPA_1c11890 00c07bccb5ec3bc7e057e31b566bf620 303 Gene3D G3DSA:3.40.50.1820 8 301 7.0E-64 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c11890 00c07bccb5ec3bc7e057e31b566bf620 303 SUPERFAMILY SSF53474 8 302 5.02E-53 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c11890 00c07bccb5ec3bc7e057e31b566bf620 303 PRINTS PR00412 Epoxide hydrolase signature 277 299 1.7E-14 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 VAPA_1c11890 00c07bccb5ec3bc7e057e31b566bf620 303 PRINTS PR00412 Epoxide hydrolase signature 55 70 1.7E-14 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 VAPA_1c11890 00c07bccb5ec3bc7e057e31b566bf620 303 PRINTS PR00412 Epoxide hydrolase signature 32 50 1.7E-14 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 VAPA_1c11890 00c07bccb5ec3bc7e057e31b566bf620 303 PRINTS PR00412 Epoxide hydrolase signature 103 116 1.7E-14 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 VAPA_1c11890 00c07bccb5ec3bc7e057e31b566bf620 303 Pfam PF00561 alpha/beta hydrolase fold 26 288 1.7E-20 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 VAPA_1c11890 00c07bccb5ec3bc7e057e31b566bf620 303 PRINTS PR00111 Alpha/beta hydrolase fold signature 55 70 2.5E-6 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 VAPA_1c11890 00c07bccb5ec3bc7e057e31b566bf620 303 PRINTS PR00111 Alpha/beta hydrolase fold signature 103 116 2.5E-6 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 VAPA_1c11890 00c07bccb5ec3bc7e057e31b566bf620 303 PRINTS PR00111 Alpha/beta hydrolase fold signature 117 130 2.5E-6 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 VAPA_1c05250 522f1ded2a137bab3051b1897e13ed61 311 SUPERFAMILY SSF53850 105 307 5.79E-27 T 12-10-2018 VAPA_1c05250 522f1ded2a137bab3051b1897e13ed61 311 Gene3D G3DSA:3.40.190.10 172 274 6.6E-44 T 12-10-2018 VAPA_1c05250 522f1ded2a137bab3051b1897e13ed61 311 Gene3D G3DSA:3.40.190.10 114 301 6.6E-44 T 12-10-2018 VAPA_1c05250 522f1ded2a137bab3051b1897e13ed61 311 Pfam PF03466 LysR substrate binding domain 105 305 2.1E-23 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_1c05250 522f1ded2a137bab3051b1897e13ed61 311 SUPERFAMILY SSF46785 17 98 1.89E-20 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c05250 522f1ded2a137bab3051b1897e13ed61 311 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 45 55 1.0E-9 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c05250 522f1ded2a137bab3051b1897e13ed61 311 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 55 66 1.0E-9 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c05250 522f1ded2a137bab3051b1897e13ed61 311 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 45 1.0E-9 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c05250 522f1ded2a137bab3051b1897e13ed61 311 Gene3D G3DSA:1.10.10.10 18 106 1.9E-21 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c05250 522f1ded2a137bab3051b1897e13ed61 311 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 19 77 2.3E-19 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c08750 3034d81a8cf2095bb45fd5c0ad9464e5 398 Gene3D G3DSA:3.40.47.10 9 281 2.3E-144 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 VAPA_1c08750 3034d81a8cf2095bb45fd5c0ad9464e5 398 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 9 396 6.4E-143 T 12-10-2018 IPR002155 Thiolase GO:0016747 VAPA_1c08750 3034d81a8cf2095bb45fd5c0ad9464e5 398 SUPERFAMILY SSF53901 6 275 9.88E-77 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 VAPA_1c08750 3034d81a8cf2095bb45fd5c0ad9464e5 398 ProSitePatterns PS00737 Thiolases signature 2. 344 360 - T 12-10-2018 IPR020613 Thiolase, conserved site GO:0016747 VAPA_1c08750 3034d81a8cf2095bb45fd5c0ad9464e5 398 Pfam PF00108 Thiolase, N-terminal domain 8 267 4.5E-77 T 12-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 VAPA_1c08750 3034d81a8cf2095bb45fd5c0ad9464e5 398 PIRSF PIRSF000429 1 398 1.8E-129 T 12-10-2018 IPR002155 Thiolase GO:0016747 VAPA_1c08750 3034d81a8cf2095bb45fd5c0ad9464e5 398 Pfam PF02803 Thiolase, C-terminal domain 275 397 1.2E-44 T 12-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 VAPA_1c08750 3034d81a8cf2095bb45fd5c0ad9464e5 398 Gene3D G3DSA:3.40.47.10 132 394 2.3E-144 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 VAPA_1c08750 3034d81a8cf2095bb45fd5c0ad9464e5 398 SUPERFAMILY SSF53901 276 397 4.61E-43 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 VAPA_1c08750 3034d81a8cf2095bb45fd5c0ad9464e5 398 ProSitePatterns PS00099 Thiolases active site. 379 392 - T 12-10-2018 IPR020610 Thiolase, active site GO:0016747 VAPA_1c08750 3034d81a8cf2095bb45fd5c0ad9464e5 398 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 90 108 - T 12-10-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0016747 VAPA_1c09380 a429c31115a3cde1152c548a70199c2b 276 Pfam PF09694 Bacterial protein of unknown function (Gcw_chp) 26 241 6.8E-38 T 12-10-2018 IPR010239 Conserved hypothetical protein CHP02001 VAPA_1c09380 a429c31115a3cde1152c548a70199c2b 276 TIGRFAM TIGR02001 gcw_chp: conserved hypothetical protein 14 236 7.3E-33 T 12-10-2018 IPR010239 Conserved hypothetical protein CHP02001 VAPA_2c05760 c8f1610549ab2ca0994b68f146c7f8fc 213 SUPERFAMILY SSF47741 129 210 1.44E-27 T 12-10-2018 IPR036884 [2Fe-2S]-binding domain superfamily VAPA_2c05760 c8f1610549ab2ca0994b68f146c7f8fc 213 SUPERFAMILY SSF54292 46 123 6.82E-27 T 12-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 VAPA_2c05760 c8f1610549ab2ca0994b68f146c7f8fc 213 Pfam PF01799 [2Fe-2S] binding domain 118 205 1.2E-29 T 12-10-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 VAPA_2c05760 c8f1610549ab2ca0994b68f146c7f8fc 213 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 51 104 5.1E-8 T 12-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 VAPA_2c05760 c8f1610549ab2ca0994b68f146c7f8fc 213 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 84 92 - T 12-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 VAPA_2c05760 c8f1610549ab2ca0994b68f146c7f8fc 213 Gene3D G3DSA:1.10.150.120 122 212 8.0E-35 T 12-10-2018 VAPA_2c05760 c8f1610549ab2ca0994b68f146c7f8fc 213 Gene3D G3DSA:3.10.20.30 37 121 1.7E-32 T 12-10-2018 IPR012675 Beta-grasp domain superfamily VAPA_1c40050 962b123c0c537ebf648b747c9cb53a9f 315 Gene3D G3DSA:1.10.10.10 1 88 7.0E-21 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c40050 962b123c0c537ebf648b747c9cb53a9f 315 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 9 67 4.2E-15 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c40050 962b123c0c537ebf648b747c9cb53a9f 315 SUPERFAMILY SSF46785 3 114 1.4E-20 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c40050 962b123c0c537ebf648b747c9cb53a9f 315 Gene3D G3DSA:3.40.190.10 166 277 4.2E-45 T 12-10-2018 VAPA_1c40050 962b123c0c537ebf648b747c9cb53a9f 315 Pfam PF03466 LysR substrate binding domain 91 300 9.2E-21 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_1c40050 962b123c0c537ebf648b747c9cb53a9f 315 Gene3D G3DSA:3.40.190.10 98 284 4.2E-45 T 12-10-2018 VAPA_1c40050 962b123c0c537ebf648b747c9cb53a9f 315 SUPERFAMILY SSF53850 92 306 8.69E-22 T 12-10-2018 VAPA_1c27920 e8327bb961721c03e19bc6f6293e92a5 94 Gene3D G3DSA:3.30.2310.20 1 90 4.1E-28 T 12-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily VAPA_1c27920 e8327bb961721c03e19bc6f6293e92a5 94 TIGRFAM TIGR02385 RelE_StbE: addiction module toxin, RelE/StbE family 3 86 1.3E-8 T 12-10-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family VAPA_1c27920 e8327bb961721c03e19bc6f6293e92a5 94 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 3 89 4.7E-17 T 12-10-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family VAPA_1c08870 3761274cb9a3d796e415ea8f3e4bce50 483 Pfam PF00206 Lyase 13 344 3.7E-95 T 12-10-2018 IPR022761 Fumarate lyase, N-terminal VAPA_1c08870 3761274cb9a3d796e415ea8f3e4bce50 483 Gene3D G3DSA:1.20.200.10 142 409 1.5E-110 T 12-10-2018 VAPA_1c08870 3761274cb9a3d796e415ea8f3e4bce50 483 Pfam PF10415 Fumarase C C-terminus 410 462 1.9E-17 T 12-10-2018 IPR018951 Fumarase C, C-terminal GO:0006099|GO:0016829 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 VAPA_1c08870 3761274cb9a3d796e415ea8f3e4bce50 483 Gene3D G3DSA:1.10.275.10 4 141 6.0E-57 T 12-10-2018 IPR024083 Fumarase/histidase, N-terminal VAPA_1c08870 3761274cb9a3d796e415ea8f3e4bce50 483 SUPERFAMILY SSF48557 4 462 3.98E-142 T 12-10-2018 IPR008948 L-Aspartase-like GO:0003824 VAPA_1c08870 3761274cb9a3d796e415ea8f3e4bce50 483 Gene3D G3DSA:1.10.40.30 410 468 3.4E-15 T 12-10-2018 VAPA_1c08870 3761274cb9a3d796e415ea8f3e4bce50 483 ProSitePatterns PS00163 Fumarate lyases signature. 319 328 - T 12-10-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 VAPA_1c08870 3761274cb9a3d796e415ea8f3e4bce50 483 PRINTS PR00149 Fumarate lyase superfamily signature 137 155 9.2E-30 T 12-10-2018 IPR000362 Fumarate lyase family VAPA_1c08870 3761274cb9a3d796e415ea8f3e4bce50 483 PRINTS PR00149 Fumarate lyase superfamily signature 273 300 9.2E-30 T 12-10-2018 IPR000362 Fumarate lyase family VAPA_1c08870 3761274cb9a3d796e415ea8f3e4bce50 483 PRINTS PR00149 Fumarate lyase superfamily signature 319 335 9.2E-30 T 12-10-2018 IPR000362 Fumarate lyase family VAPA_1c08870 3761274cb9a3d796e415ea8f3e4bce50 483 PRINTS PR00149 Fumarate lyase superfamily signature 182 200 9.2E-30 T 12-10-2018 IPR000362 Fumarate lyase family VAPA_1c29850 bf9556c3126270e0e6e460950c99ae28 183 Gene3D G3DSA:3.40.50.1240 1 182 6.4E-28 T 12-10-2018 IPR029033 Histidine phosphatase superfamily VAPA_1c29850 bf9556c3126270e0e6e460950c99ae28 183 SMART SM00855 2 151 2.8E-9 T 12-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 VAPA_1c29850 bf9556c3126270e0e6e460950c99ae28 183 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 3 153 1.1E-24 T 12-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 VAPA_1c29850 bf9556c3126270e0e6e460950c99ae28 183 SUPERFAMILY SSF53254 1 158 2.78E-29 T 12-10-2018 IPR029033 Histidine phosphatase superfamily VAPA_1c20150 ea0233465b3e6e3d2ebf3a760fe00f4f 246 Gene3D G3DSA:1.20.120.530 107 219 4.3E-13 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal VAPA_1c20150 ea0233465b3e6e3d2ebf3a760fe00f4f 246 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 55 71 3.1E-10 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_1c20150 ea0233465b3e6e3d2ebf3a760fe00f4f 246 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 41 55 3.1E-10 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_1c20150 ea0233465b3e6e3d2ebf3a760fe00f4f 246 SUPERFAMILY SSF46785 14 87 4.18E-19 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c20150 ea0233465b3e6e3d2ebf3a760fe00f4f 246 Pfam PF00392 Bacterial regulatory proteins, gntR family 20 78 2.0E-18 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_1c20150 ea0233465b3e6e3d2ebf3a760fe00f4f 246 SUPERFAMILY SSF48008 109 214 2.62E-11 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal VAPA_1c20150 ea0233465b3e6e3d2ebf3a760fe00f4f 246 SMART SM00345 22 83 3.0E-17 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_1c20150 ea0233465b3e6e3d2ebf3a760fe00f4f 246 Gene3D G3DSA:1.10.10.10 15 85 1.9E-21 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c20150 ea0233465b3e6e3d2ebf3a760fe00f4f 246 Pfam PF07729 FCD domain 109 216 9.6E-14 T 12-10-2018 IPR011711 GntR, C-terminal VAPA_1c20150 ea0233465b3e6e3d2ebf3a760fe00f4f 246 SMART SM00895 108 214 6.1E-5 T 12-10-2018 IPR011711 GntR, C-terminal VAPA_1c17810 9cf09f548ff46af5967381472a67a9dc 364 SMART SM00729 75 298 0.0029 T 12-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 VAPA_1c17810 9cf09f548ff46af5967381472a67a9dc 364 Gene3D G3DSA:3.80.30.30 117 257 1.4E-6 T 12-10-2018 VAPA_1c17810 9cf09f548ff46af5967381472a67a9dc 364 SUPERFAMILY SSF102114 58 273 3.14E-10 T 12-10-2018 VAPA_1c17810 9cf09f548ff46af5967381472a67a9dc 364 Pfam PF04055 Radical SAM superfamily 80 256 1.9E-11 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 VAPA_1c04700 e74b71fa69c22284ba07895bdc05a466 475 PIRSF PIRSF000204 1 475 1.3E-203 T 12-10-2018 IPR012136 NADP transhydrogenase, beta subunit GO:0008750|GO:0016021|GO:0050661|GO:0055114 KEGG: 00760+1.6.1.2 VAPA_1c04700 e74b71fa69c22284ba07895bdc05a466 475 SUPERFAMILY SSF52467 304 475 5.95E-71 T 12-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily VAPA_1c04700 e74b71fa69c22284ba07895bdc05a466 475 Gene3D G3DSA:3.40.50.1220 295 475 1.8E-81 T 12-10-2018 VAPA_1c04700 e74b71fa69c22284ba07895bdc05a466 475 Pfam PF02233 NAD(P) transhydrogenase beta subunit 7 471 5.0E-186 T 12-10-2018 IPR034300 NADP transhydrogenase beta-like domain KEGG: 00760+1.6.1.2|Reactome: R-HSA-71403 VAPA_1c25250 37fda1b5a20725439ee89fa880fbdce4 442 Pfam PF00512 His Kinase A (phospho-acceptor) domain 222 285 1.7E-12 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 VAPA_1c25250 37fda1b5a20725439ee89fa880fbdce4 442 Gene3D G3DSA:1.10.287.130 172 287 3.4E-20 T 12-10-2018 VAPA_1c25250 37fda1b5a20725439ee89fa880fbdce4 442 Gene3D G3DSA:3.30.565.10 290 439 8.2E-33 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_1c25250 37fda1b5a20725439ee89fa880fbdce4 442 Pfam PF08521 Two-component sensor kinase N-terminal 22 142 4.3E-5 T 12-10-2018 IPR013727 Two-component sensor kinase, N-terminal VAPA_1c25250 37fda1b5a20725439ee89fa880fbdce4 442 SMART SM00388 221 286 9.2E-13 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 VAPA_1c25250 37fda1b5a20725439ee89fa880fbdce4 442 SUPERFAMILY SSF55874 276 430 4.32E-33 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_1c25250 37fda1b5a20725439ee89fa880fbdce4 442 SUPERFAMILY SSF47384 204 285 1.04E-14 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 VAPA_1c25250 37fda1b5a20725439ee89fa880fbdce4 442 SMART SM00387 332 442 2.1E-30 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase VAPA_1c25250 37fda1b5a20725439ee89fa880fbdce4 442 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 333 430 3.4E-18 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase VAPA_1c25250 37fda1b5a20725439ee89fa880fbdce4 442 PRINTS PR00344 Bacterial sensor protein C-terminal signature 369 383 5.9E-10 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c25250 37fda1b5a20725439ee89fa880fbdce4 442 PRINTS PR00344 Bacterial sensor protein C-terminal signature 387 397 5.9E-10 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c25250 37fda1b5a20725439ee89fa880fbdce4 442 PRINTS PR00344 Bacterial sensor protein C-terminal signature 401 419 5.9E-10 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c00480 d815ec6833fd1e616197826c8a3af382 182 SUPERFAMILY SSF53474 7 173 6.55E-33 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c00480 d815ec6833fd1e616197826c8a3af382 182 Gene3D G3DSA:3.40.50.1820 1 181 2.2E-49 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c00480 d815ec6833fd1e616197826c8a3af382 182 Pfam PF06821 Serine hydrolase 7 175 1.2E-58 T 12-10-2018 IPR010662 Putative hydrolase RBBP9/YdeN GO:0016787 VAPA_1c39950 fe1dfadd480ae6a744f1df8f95e4ec18 486 Gene3D G3DSA:3.40.50.300 1 215 2.0E-79 T 12-10-2018 VAPA_1c39950 fe1dfadd480ae6a744f1df8f95e4ec18 486 Pfam PF00270 DEAD/DEAH box helicase 27 201 8.8E-51 T 12-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 VAPA_1c39950 fe1dfadd480ae6a744f1df8f95e4ec18 486 SMART SM00490 263 344 5.5E-33 T 12-10-2018 IPR001650 Helicase, C-terminal VAPA_1c39950 fe1dfadd480ae6a744f1df8f95e4ec18 486 SMART SM00487 22 227 6.1E-63 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain VAPA_1c39950 fe1dfadd480ae6a744f1df8f95e4ec18 486 Gene3D G3DSA:3.40.50.300 218 388 4.4E-49 T 12-10-2018 VAPA_1c39950 fe1dfadd480ae6a744f1df8f95e4ec18 486 Pfam PF00271 Helicase conserved C-terminal domain 236 344 2.1E-28 T 12-10-2018 IPR001650 Helicase, C-terminal VAPA_1c39950 fe1dfadd480ae6a744f1df8f95e4ec18 486 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 158 166 - T 12-10-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site VAPA_1c39950 fe1dfadd480ae6a744f1df8f95e4ec18 486 SUPERFAMILY SSF52540 79 362 6.75E-74 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c09130 d8b0656c1eccfd7c3a8a0ae81d23f4df 345 SUPERFAMILY SSF52540 15 263 4.61E-72 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c09130 d8b0656c1eccfd7c3a8a0ae81d23f4df 345 Pfam PF00005 ABC transporter 42 191 6.8E-33 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c09130 d8b0656c1eccfd7c3a8a0ae81d23f4df 345 Gene3D G3DSA:3.40.50.300 13 336 1.0E-99 T 12-10-2018 VAPA_1c09130 d8b0656c1eccfd7c3a8a0ae81d23f4df 345 ProSitePatterns PS00211 ABC transporters family signature. 164 178 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_1c09130 d8b0656c1eccfd7c3a8a0ae81d23f4df 345 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 244 308 5.2E-19 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 VAPA_1c09130 d8b0656c1eccfd7c3a8a0ae81d23f4df 345 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 241 327 1.9E-24 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 VAPA_1c09130 d8b0656c1eccfd7c3a8a0ae81d23f4df 345 SMART SM00382 50 241 4.2E-18 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c02760 a437acac5d04fb70afca73b9c3cd23da 112 ProSitePatterns PS00638 P-II protein C-terminal region signature. 83 96 - T 12-10-2018 IPR017918 Nitrogen regulatory protein PII, conserved site GO:0006808|GO:0030234 VAPA_1c02760 a437acac5d04fb70afca73b9c3cd23da 112 Pfam PF00543 Nitrogen regulatory protein P-II 4 105 3.5E-42 T 12-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 VAPA_1c02760 a437acac5d04fb70afca73b9c3cd23da 112 SMART SM00938 4 105 4.8E-67 T 12-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 VAPA_1c02760 a437acac5d04fb70afca73b9c3cd23da 112 PRINTS PR00340 P-II protein signature 83 103 7.1E-44 T 12-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 VAPA_1c02760 a437acac5d04fb70afca73b9c3cd23da 112 PRINTS PR00340 P-II protein signature 23 41 7.1E-44 T 12-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 VAPA_1c02760 a437acac5d04fb70afca73b9c3cd23da 112 PRINTS PR00340 P-II protein signature 52 75 7.1E-44 T 12-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 VAPA_1c02760 a437acac5d04fb70afca73b9c3cd23da 112 PRINTS PR00340 P-II protein signature 2 17 7.1E-44 T 12-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 VAPA_1c02760 a437acac5d04fb70afca73b9c3cd23da 112 ProSitePatterns PS00496 P-II protein uridylation site. 46 51 - T 12-10-2018 IPR002332 Nitrogen regulatory protein P-II, urydylation site GO:0006808|GO:0030234 VAPA_1c02760 a437acac5d04fb70afca73b9c3cd23da 112 SUPERFAMILY SSF54913 1 112 7.31E-46 T 12-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta VAPA_1c02760 a437acac5d04fb70afca73b9c3cd23da 112 Gene3D G3DSA:3.30.70.120 1 112 1.4E-46 T 12-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal VAPA_1c02760 a437acac5d04fb70afca73b9c3cd23da 112 PIRSF PIRSF039144 1 112 2.3E-54 T 12-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 VAPA_1c17770 1a194c19a3fa7dc9bb8d26bc2e1ac594 348 SUPERFAMILY SSF55961 180 337 8.37E-11 T 12-10-2018 VAPA_1c17770 1a194c19a3fa7dc9bb8d26bc2e1ac594 348 Gene3D G3DSA:3.30.530.20 177 341 2.9E-8 T 12-10-2018 IPR023393 START-like domain superfamily VAPA_1c12960 bfb8af13779f08ec31ae25af0ce70150 382 SUPERFAMILY SSF53822 23 380 3.93E-74 T 12-10-2018 IPR028082 Periplasmic binding protein-like I VAPA_1c12960 bfb8af13779f08ec31ae25af0ce70150 382 Pfam PF13458 Periplasmic binding protein 24 370 7.8E-52 T 12-10-2018 IPR028081 Leucine-binding protein domain VAPA_1c12960 bfb8af13779f08ec31ae25af0ce70150 382 Gene3D G3DSA:3.40.50.2300 141 373 1.8E-120 T 12-10-2018 VAPA_1c12960 bfb8af13779f08ec31ae25af0ce70150 382 Gene3D G3DSA:3.40.50.2300 26 364 1.8E-120 T 12-10-2018 VAPA_1c37780 b8c44aadda5531516ecca8332d263443 418 TIGRFAM TIGR03440 egtB_TIGR03440: ergothioneine biosynthesis protein EgtB 15 415 1.0E-152 T 12-10-2018 IPR017806 Ergothioneine biosynthesis protein EgtB GO:0052699 KEGG: 00340+1.14.99.50|MetaCyc: PWY-7255 VAPA_1c37780 b8c44aadda5531516ecca8332d263443 418 Pfam PF12867 DinB superfamily 18 152 2.0E-12 T 12-10-2018 IPR024775 DinB-like domain VAPA_1c37780 b8c44aadda5531516ecca8332d263443 418 Pfam PF03781 Sulfatase-modifying factor enzyme 1 338 416 9.4E-6 T 12-10-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 VAPA_1c37780 b8c44aadda5531516ecca8332d263443 418 Pfam PF03781 Sulfatase-modifying factor enzyme 1 190 333 9.3E-19 T 12-10-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 VAPA_1c37780 b8c44aadda5531516ecca8332d263443 418 Gene3D G3DSA:3.90.1580.10 186 336 1.6E-23 T 12-10-2018 VAPA_1c37780 b8c44aadda5531516ecca8332d263443 418 SUPERFAMILY SSF56436 188 417 2.67E-60 T 12-10-2018 IPR016187 C-type lectin fold VAPA_1c37780 b8c44aadda5531516ecca8332d263443 418 Gene3D G3DSA:3.90.1580.10 337 418 3.8E-8 T 12-10-2018 VAPA_1c19080 ec653971aaf8ad730963bbf8bcae8acc 237 SUPERFAMILY SSF46785 1 60 2.22E-10 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c19080 ec653971aaf8ad730963bbf8bcae8acc 237 Pfam PF08279 HTH domain 6 59 1.6E-16 T 12-10-2018 IPR013196 Helix-turn-helix, type 11 VAPA_1c19080 ec653971aaf8ad730963bbf8bcae8acc 237 Pfam PF13280 WYL domain 136 228 3.7E-19 T 12-10-2018 IPR026881 WYL domain VAPA_1c19080 ec653971aaf8ad730963bbf8bcae8acc 237 Gene3D G3DSA:1.10.10.10 1 62 5.7E-15 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c49620 618941a4748c807bdd1d9c3bf6306c25 1076 Pfam PF00258 Flavodoxin 504 634 1.7E-25 T 12-10-2018 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 VAPA_1c49620 618941a4748c807bdd1d9c3bf6306c25 1076 SUPERFAMILY SSF63380 680 914 2.02E-59 T 12-10-2018 IPR017938 Riboflavin synthase-like beta-barrel VAPA_1c49620 618941a4748c807bdd1d9c3bf6306c25 1076 Gene3D G3DSA:2.40.30.10 686 908 1.2E-67 T 12-10-2018 VAPA_1c49620 618941a4748c807bdd1d9c3bf6306c25 1076 Pfam PF00667 FAD binding domain 684 898 7.9E-36 T 12-10-2018 IPR003097 Sulfite reductase [NADPH] flavoprotein alpha-component-like, FAD-binding GO:0016491|GO:0055114 VAPA_1c49620 618941a4748c807bdd1d9c3bf6306c25 1076 Pfam PF00175 Oxidoreductase NAD-binding domain 932 1041 3.0E-16 T 12-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 VAPA_1c49620 618941a4748c807bdd1d9c3bf6306c25 1076 PIRSF PIRSF000209 4 1076 0.0 T 12-10-2018 IPR023206 Bifunctional cytochrome P450/NADPH--cytochrome P450 reductase GO:0003958|GO:0055114|GO:0070330 KEGG: 00071+1.14.14.1|KEGG: 00140+1.14.14.1|KEGG: 00232+1.14.14.1|KEGG: 00380+1.14.14.1|KEGG: 00590+1.14.14.1|KEGG: 00591+1.14.14.1|KEGG: 00627+1.14.14.1|KEGG: 00830+1.14.14.1|KEGG: 00980+1.14.14.1|KEGG: 00982+1.14.14.1|MetaCyc: PWY-5451|MetaCyc: PWY-5665|MetaCyc: PWY-6398|MetaCyc: PWY-6992|MetaCyc: PWY-7466|MetaCyc: PWY-7826 VAPA_1c49620 618941a4748c807bdd1d9c3bf6306c25 1076 Gene3D G3DSA:3.40.50.360 470 656 2.7E-45 T 12-10-2018 IPR029039 Flavoprotein-like superfamily VAPA_1c49620 618941a4748c807bdd1d9c3bf6306c25 1076 SUPERFAMILY SSF48264 8 462 2.23E-109 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 VAPA_1c49620 618941a4748c807bdd1d9c3bf6306c25 1076 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 404 413 - T 12-10-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 VAPA_1c49620 618941a4748c807bdd1d9c3bf6306c25 1076 Gene3D G3DSA:1.20.990.10 729 856 1.2E-67 T 12-10-2018 IPR023173 NADPH-cytochrome p450 reductase, FAD-binding, alpha-helical domain superfamily GO:0016491|GO:0055114 VAPA_1c49620 618941a4748c807bdd1d9c3bf6306c25 1076 SUPERFAMILY SSF52218 498 649 1.35E-40 T 12-10-2018 IPR029039 Flavoprotein-like superfamily VAPA_1c49620 618941a4748c807bdd1d9c3bf6306c25 1076 Gene3D G3DSA:1.10.630.10 6 469 1.2E-144 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 VAPA_1c49620 618941a4748c807bdd1d9c3bf6306c25 1076 PRINTS PR00369 Flavodoxin signature 604 623 1.4E-9 T 12-10-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 VAPA_1c49620 618941a4748c807bdd1d9c3bf6306c25 1076 PRINTS PR00369 Flavodoxin signature 579 589 1.4E-9 T 12-10-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 VAPA_1c49620 618941a4748c807bdd1d9c3bf6306c25 1076 PRINTS PR00369 Flavodoxin signature 502 515 1.4E-9 T 12-10-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 VAPA_1c49620 618941a4748c807bdd1d9c3bf6306c25 1076 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 1003 1019 3.7E-33 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 VAPA_1c49620 618941a4748c807bdd1d9c3bf6306c25 1076 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 1026 1034 3.7E-33 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 VAPA_1c49620 618941a4748c807bdd1d9c3bf6306c25 1076 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 719 729 3.7E-33 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 VAPA_1c49620 618941a4748c807bdd1d9c3bf6306c25 1076 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 858 865 3.7E-33 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 VAPA_1c49620 618941a4748c807bdd1d9c3bf6306c25 1076 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 973 984 3.7E-33 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 VAPA_1c49620 618941a4748c807bdd1d9c3bf6306c25 1076 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 893 902 3.7E-33 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 VAPA_1c49620 618941a4748c807bdd1d9c3bf6306c25 1076 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 960 969 3.7E-33 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 VAPA_1c49620 618941a4748c807bdd1d9c3bf6306c25 1076 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 931 950 3.7E-33 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 VAPA_1c49620 618941a4748c807bdd1d9c3bf6306c25 1076 SUPERFAMILY SSF52343 919 1073 6.42E-46 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain VAPA_1c49620 618941a4748c807bdd1d9c3bf6306c25 1076 Gene3D G3DSA:3.40.50.80 920 1075 4.1E-57 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain VAPA_1c49620 618941a4748c807bdd1d9c3bf6306c25 1076 Pfam PF00067 Cytochrome P450 12 458 4.8E-86 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 VAPA_1c48900 96ef2e31fef79aa7c2957aa2b4971860 416 SUPERFAMILY SSF55031 216 322 1.06E-21 T 12-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain VAPA_1c48900 96ef2e31fef79aa7c2957aa2b4971860 416 Pfam PF01546 Peptidase family M20/M25/M40 109 410 3.4E-29 T 12-10-2018 IPR002933 Peptidase M20 GO:0016787 VAPA_1c48900 96ef2e31fef79aa7c2957aa2b4971860 416 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 108 117 - T 12-10-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 VAPA_1c48900 96ef2e31fef79aa7c2957aa2b4971860 416 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 140 179 - T 12-10-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 VAPA_1c48900 96ef2e31fef79aa7c2957aa2b4971860 416 Pfam PF07687 Peptidase dimerisation domain 213 311 3.5E-18 T 12-10-2018 IPR011650 Peptidase M20, dimerisation domain VAPA_1c48900 96ef2e31fef79aa7c2957aa2b4971860 416 Gene3D G3DSA:3.30.70.360 215 324 9.8E-138 T 12-10-2018 VAPA_1c48900 96ef2e31fef79aa7c2957aa2b4971860 416 SUPERFAMILY SSF53187 34 412 2.32E-58 T 12-10-2018 VAPA_1c48900 96ef2e31fef79aa7c2957aa2b4971860 416 PIRSF PIRSF037238 30 413 2.6E-131 T 12-10-2018 IPR017150 Peptidase M20, glutamate carboxypeptidase VAPA_1c48900 96ef2e31fef79aa7c2957aa2b4971860 416 Gene3D G3DSA:3.40.630.10 47 401 9.8E-138 T 12-10-2018 VAPA_1c30960 c2b0e0642a6bfcbddf859633fa922ac1 309 Gene3D G3DSA:1.10.8.60 206 297 1.0E-25 T 12-10-2018 VAPA_1c30960 c2b0e0642a6bfcbddf859633fa922ac1 309 PRINTS PR00819 CbxX/CfqX superfamily signature 72 87 2.5E-72 T 12-10-2018 IPR000641 CbxX/CfqX GO:0005524 VAPA_1c30960 c2b0e0642a6bfcbddf859633fa922ac1 309 PRINTS PR00819 CbxX/CfqX superfamily signature 193 212 2.5E-72 T 12-10-2018 IPR000641 CbxX/CfqX GO:0005524 VAPA_1c30960 c2b0e0642a6bfcbddf859633fa922ac1 309 PRINTS PR00819 CbxX/CfqX superfamily signature 155 167 2.5E-72 T 12-10-2018 IPR000641 CbxX/CfqX GO:0005524 VAPA_1c30960 c2b0e0642a6bfcbddf859633fa922ac1 309 PRINTS PR00819 CbxX/CfqX superfamily signature 32 46 2.5E-72 T 12-10-2018 IPR000641 CbxX/CfqX GO:0005524 VAPA_1c30960 c2b0e0642a6bfcbddf859633fa922ac1 309 PRINTS PR00819 CbxX/CfqX superfamily signature 110 124 2.5E-72 T 12-10-2018 IPR000641 CbxX/CfqX GO:0005524 VAPA_1c30960 c2b0e0642a6bfcbddf859633fa922ac1 309 PRINTS PR00819 CbxX/CfqX superfamily signature 124 143 2.5E-72 T 12-10-2018 IPR000641 CbxX/CfqX GO:0005524 VAPA_1c30960 c2b0e0642a6bfcbddf859633fa922ac1 309 PRINTS PR00819 CbxX/CfqX superfamily signature 250 262 2.5E-72 T 12-10-2018 IPR000641 CbxX/CfqX GO:0005524 VAPA_1c30960 c2b0e0642a6bfcbddf859633fa922ac1 309 PRINTS PR00819 CbxX/CfqX superfamily signature 176 193 2.5E-72 T 12-10-2018 IPR000641 CbxX/CfqX GO:0005524 VAPA_1c30960 c2b0e0642a6bfcbddf859633fa922ac1 309 Gene3D G3DSA:3.40.50.300 9 205 9.7E-57 T 12-10-2018 VAPA_1c30960 c2b0e0642a6bfcbddf859633fa922ac1 309 SMART SM00382 69 208 2.6E-5 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c30960 c2b0e0642a6bfcbddf859633fa922ac1 309 SUPERFAMILY SSF52540 27 272 2.89E-38 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c30960 c2b0e0642a6bfcbddf859633fa922ac1 309 PRINTS PR00820 CbxX/CfqX protein signature 45 59 1.8E-49 T 12-10-2018 IPR000470 CbxX/CfqX, monofunctional GO:0005524 VAPA_1c30960 c2b0e0642a6bfcbddf859633fa922ac1 309 PRINTS PR00820 CbxX/CfqX protein signature 27 41 1.8E-49 T 12-10-2018 IPR000470 CbxX/CfqX, monofunctional GO:0005524 VAPA_1c30960 c2b0e0642a6bfcbddf859633fa922ac1 309 PRINTS PR00820 CbxX/CfqX protein signature 143 156 1.8E-49 T 12-10-2018 IPR000470 CbxX/CfqX, monofunctional GO:0005524 VAPA_1c30960 c2b0e0642a6bfcbddf859633fa922ac1 309 PRINTS PR00820 CbxX/CfqX protein signature 86 101 1.8E-49 T 12-10-2018 IPR000470 CbxX/CfqX, monofunctional GO:0005524 VAPA_1c30960 c2b0e0642a6bfcbddf859633fa922ac1 309 PRINTS PR00820 CbxX/CfqX protein signature 281 295 1.8E-49 T 12-10-2018 IPR000470 CbxX/CfqX, monofunctional GO:0005524 VAPA_1c30960 c2b0e0642a6bfcbddf859633fa922ac1 309 PRINTS PR00820 CbxX/CfqX protein signature 242 253 1.8E-49 T 12-10-2018 IPR000470 CbxX/CfqX, monofunctional GO:0005524 VAPA_1c30960 c2b0e0642a6bfcbddf859633fa922ac1 309 PRINTS PR00820 CbxX/CfqX protein signature 257 268 1.8E-49 T 12-10-2018 IPR000470 CbxX/CfqX, monofunctional GO:0005524 VAPA_1c30960 c2b0e0642a6bfcbddf859633fa922ac1 309 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 74 187 4.5E-15 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 VAPA_1c30960 c2b0e0642a6bfcbddf859633fa922ac1 309 TIGRFAM TIGR02880 cbbX_cfxQ: CbbX protein 19 295 8.2E-153 T 12-10-2018 IPR000470 CbxX/CfqX, monofunctional GO:0005524 VAPA_1c38270 9b0d35c2f5d7a71c1243970cea59290f 225 Pfam PF00043 Glutathione S-transferase, C-terminal domain 118 196 2.9E-10 T 12-10-2018 IPR004046 Glutathione S-transferase, C-terminal VAPA_1c38270 9b0d35c2f5d7a71c1243970cea59290f 225 SUPERFAMILY SSF52833 4 107 1.56E-26 T 12-10-2018 IPR036249 Thioredoxin-like superfamily VAPA_1c38270 9b0d35c2f5d7a71c1243970cea59290f 225 Pfam PF13417 Glutathione S-transferase, N-terminal domain 8 85 1.8E-20 T 12-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 VAPA_1c38270 9b0d35c2f5d7a71c1243970cea59290f 225 Gene3D G3DSA:3.40.30.10 4 84 3.8E-26 T 12-10-2018 VAPA_1c38270 9b0d35c2f5d7a71c1243970cea59290f 225 SUPERFAMILY SSF47616 80 216 7.8E-34 T 12-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily VAPA_1c38270 9b0d35c2f5d7a71c1243970cea59290f 225 Gene3D G3DSA:1.20.1050.10 85 216 1.4E-28 T 12-10-2018 VAPA_2c08850 ab3dddfb12357d7434f4a6f34a80883c 349 Gene3D G3DSA:1.20.1050.10 208 322 7.2E-9 T 12-10-2018 VAPA_2c08850 ab3dddfb12357d7434f4a6f34a80883c 349 SUPERFAMILY SSF52833 31 146 8.75E-6 T 12-10-2018 IPR036249 Thioredoxin-like superfamily VAPA_2c08850 ab3dddfb12357d7434f4a6f34a80883c 349 Pfam PF13410 Glutathione S-transferase, C-terminal domain 244 312 1.3E-6 T 12-10-2018 VAPA_2c08850 ab3dddfb12357d7434f4a6f34a80883c 349 SUPERFAMILY SSF47616 239 319 1.67E-10 T 12-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily VAPA_2c08850 ab3dddfb12357d7434f4a6f34a80883c 349 Pfam PF13409 Glutathione S-transferase, N-terminal domain 43 145 1.0E-6 T 12-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 VAPA_2c08850 ab3dddfb12357d7434f4a6f34a80883c 349 Gene3D G3DSA:3.40.30.10 35 176 1.0E-8 T 12-10-2018 VAPA_1c02240 119993d01f0d4e4fcd7f97892ab4c8ed 166 Gene3D G3DSA:1.10.150.120 83 166 5.9E-27 T 12-10-2018 VAPA_1c02240 119993d01f0d4e4fcd7f97892ab4c8ed 166 SUPERFAMILY SSF47741 92 162 4.71E-28 T 12-10-2018 IPR036884 [2Fe-2S]-binding domain superfamily VAPA_1c02240 119993d01f0d4e4fcd7f97892ab4c8ed 166 SUPERFAMILY SSF54292 9 95 2.49E-21 T 12-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 VAPA_1c02240 119993d01f0d4e4fcd7f97892ab4c8ed 166 Gene3D G3DSA:3.10.20.30 6 82 2.9E-25 T 12-10-2018 IPR012675 Beta-grasp domain superfamily VAPA_1c02240 119993d01f0d4e4fcd7f97892ab4c8ed 166 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 13 60 4.3E-7 T 12-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 VAPA_1c02240 119993d01f0d4e4fcd7f97892ab4c8ed 166 Pfam PF01799 [2Fe-2S] binding domain 81 153 1.2E-25 T 12-10-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 VAPA_1c02240 119993d01f0d4e4fcd7f97892ab4c8ed 166 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 47 55 - T 12-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 VAPA_1c36840 5a921f8eac2fd5ac9441dfaa70e0bbc1 353 Pfam PF00459 Inositol monophosphatase family 6 263 1.0E-66 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 VAPA_1c36840 5a921f8eac2fd5ac9441dfaa70e0bbc1 353 Gene3D G3DSA:3.30.540.10 2 146 5.8E-51 T 12-10-2018 VAPA_1c36840 5a921f8eac2fd5ac9441dfaa70e0bbc1 353 SUPERFAMILY SSF56655 3 269 1.57E-85 T 12-10-2018 VAPA_1c36840 5a921f8eac2fd5ac9441dfaa70e0bbc1 353 ProSitePatterns PS00630 Inositol monophosphatase family signature 2. 217 231 - T 12-10-2018 IPR020550 Inositol monophosphatase, conserved site GO:0046854 VAPA_1c36840 5a921f8eac2fd5ac9441dfaa70e0bbc1 353 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 87 100 - T 12-10-2018 IPR020583 Inositol monophosphatase, metal-binding site VAPA_1c36840 5a921f8eac2fd5ac9441dfaa70e0bbc1 353 PRINTS PR00377 Inositol monophosphatase superfamily signature 87 103 3.2E-60 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 VAPA_1c36840 5a921f8eac2fd5ac9441dfaa70e0bbc1 353 PRINTS PR00377 Inositol monophosphatase superfamily signature 214 238 3.2E-60 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 VAPA_1c36840 5a921f8eac2fd5ac9441dfaa70e0bbc1 353 PRINTS PR00377 Inositol monophosphatase superfamily signature 43 63 3.2E-60 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 VAPA_1c36840 5a921f8eac2fd5ac9441dfaa70e0bbc1 353 PRINTS PR00377 Inositol monophosphatase superfamily signature 136 159 3.2E-60 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 VAPA_1c36840 5a921f8eac2fd5ac9441dfaa70e0bbc1 353 PRINTS PR00377 Inositol monophosphatase superfamily signature 65 81 3.2E-60 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 VAPA_1c36840 5a921f8eac2fd5ac9441dfaa70e0bbc1 353 PRINTS PR00377 Inositol monophosphatase superfamily signature 183 204 3.2E-60 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 VAPA_1c36840 5a921f8eac2fd5ac9441dfaa70e0bbc1 353 PRINTS PR01959 SuhB family inositol monophosphatase signature 162 188 5.0E-27 T 12-10-2018 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 VAPA_1c36840 5a921f8eac2fd5ac9441dfaa70e0bbc1 353 PRINTS PR01959 SuhB family inositol monophosphatase signature 22 44 5.0E-27 T 12-10-2018 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 VAPA_1c36840 5a921f8eac2fd5ac9441dfaa70e0bbc1 353 PRINTS PR01959 SuhB family inositol monophosphatase signature 110 129 5.0E-27 T 12-10-2018 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 VAPA_1c36840 5a921f8eac2fd5ac9441dfaa70e0bbc1 353 PRINTS PR01959 SuhB family inositol monophosphatase signature 204 216 5.0E-27 T 12-10-2018 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 VAPA_1c36840 5a921f8eac2fd5ac9441dfaa70e0bbc1 353 Gene3D G3DSA:3.40.190.80 147 283 5.4E-35 T 12-10-2018 VAPA_1c29350 2f2551036596780cfc40764aeecb71b3 1082 SMART SM00851 962 1049 3.4E-30 T 12-10-2018 IPR011607 Methylglyoxal synthase-like domain VAPA_1c29350 2f2551036596780cfc40764aeecb71b3 1082 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 711 725 - T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 VAPA_1c29350 2f2551036596780cfc40764aeecb71b3 1082 SMART SM01096 426 549 1.2E-76 T 12-10-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 VAPA_1c29350 2f2551036596780cfc40764aeecb71b3 1082 SUPERFAMILY SSF52440 1 134 8.92E-47 T 12-10-2018 IPR016185 Pre-ATP-grasp domain superfamily VAPA_1c29350 2f2551036596780cfc40764aeecb71b3 1082 SUPERFAMILY SSF48108 403 555 3.4E-53 T 12-10-2018 IPR036897 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 VAPA_1c29350 2f2551036596780cfc40764aeecb71b3 1082 Gene3D G3DSA:3.30.470.20 667 942 3.5E-116 T 12-10-2018 VAPA_1c29350 2f2551036596780cfc40764aeecb71b3 1082 SUPERFAMILY SSF52440 558 677 2.88E-50 T 12-10-2018 IPR016185 Pre-ATP-grasp domain superfamily VAPA_1c29350 2f2551036596780cfc40764aeecb71b3 1082 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 675 881 9.4E-38 T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 VAPA_1c29350 2f2551036596780cfc40764aeecb71b3 1082 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 135 341 2.3E-71 T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 VAPA_1c29350 2f2551036596780cfc40764aeecb71b3 1082 SUPERFAMILY SSF56059 675 940 6.54E-102 T 12-10-2018 VAPA_1c29350 2f2551036596780cfc40764aeecb71b3 1082 Gene3D G3DSA:1.10.1030.10 410 555 3.3E-49 T 12-10-2018 IPR036897 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 VAPA_1c29350 2f2551036596780cfc40764aeecb71b3 1082 Gene3D G3DSA:3.40.50.1380 943 1080 4.4E-38 T 12-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily VAPA_1c29350 2f2551036596780cfc40764aeecb71b3 1082 Gene3D G3DSA:3.40.50.20 1 113 3.2E-48 T 12-10-2018 VAPA_1c29350 2f2551036596780cfc40764aeecb71b3 1082 SUPERFAMILY SSF56059 135 408 1.47E-108 T 12-10-2018 VAPA_1c29350 2f2551036596780cfc40764aeecb71b3 1082 Hamap MF_01210_B Carbamoyl-phosphate synthase large chain [carB]. 1 1070 13.108 T 12-10-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 VAPA_1c29350 2f2551036596780cfc40764aeecb71b3 1082 Pfam PF02142 MGS-like domain 963 1048 1.0E-19 T 12-10-2018 IPR011607 Methylglyoxal synthase-like domain VAPA_1c29350 2f2551036596780cfc40764aeecb71b3 1082 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 304 311 - T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 VAPA_1c29350 2f2551036596780cfc40764aeecb71b3 1082 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 175 187 6.8E-66 T 12-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 VAPA_1c29350 2f2551036596780cfc40764aeecb71b3 1082 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 304 333 6.8E-66 T 12-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 VAPA_1c29350 2f2551036596780cfc40764aeecb71b3 1082 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 48 58 6.8E-66 T 12-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 VAPA_1c29350 2f2551036596780cfc40764aeecb71b3 1082 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 19 33 6.8E-66 T 12-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 VAPA_1c29350 2f2551036596780cfc40764aeecb71b3 1082 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 211 230 6.8E-66 T 12-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 VAPA_1c29350 2f2551036596780cfc40764aeecb71b3 1082 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 387 405 6.8E-66 T 12-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 VAPA_1c29350 2f2551036596780cfc40764aeecb71b3 1082 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 246 263 6.8E-66 T 12-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 VAPA_1c29350 2f2551036596780cfc40764aeecb71b3 1082 TIGRFAM TIGR01369 CPSaseII_lrg: carbamoyl-phosphate synthase, large subunit 2 1059 0.0 T 12-10-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 VAPA_1c29350 2f2551036596780cfc40764aeecb71b3 1082 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 845 852 - T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 VAPA_1c29350 2f2551036596780cfc40764aeecb71b3 1082 Hamap MF_01210_A Carbamoyl-phosphate synthase large chain [carB]. 5 1075 13.248 T 12-10-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 VAPA_1c29350 2f2551036596780cfc40764aeecb71b3 1082 Pfam PF02787 Carbamoyl-phosphate synthetase large chain, oligomerisation domain 429 549 2.2E-41 T 12-10-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 VAPA_1c29350 2f2551036596780cfc40764aeecb71b3 1082 Gene3D G3DSA:3.40.50.20 556 664 1.3E-49 T 12-10-2018 VAPA_1c29350 2f2551036596780cfc40764aeecb71b3 1082 SUPERFAMILY SSF52335 942 1078 8.5E-40 T 12-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily VAPA_1c29350 2f2551036596780cfc40764aeecb71b3 1082 Gene3D G3DSA:3.30.470.20 126 409 1.3E-129 T 12-10-2018 VAPA_1c52540 36da9b03272a1c30073a58509443af52 285 Hamap MF_01925 Pyrroline-5-carboxylate reductase [proC]. 17 278 25.644 T 12-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 VAPA_1c52540 36da9b03272a1c30073a58509443af52 285 PIRSF PIRSF000193 18 281 7.9E-70 T 12-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 VAPA_1c52540 36da9b03272a1c30073a58509443af52 285 Gene3D G3DSA:1.10.3730.10 176 283 6.5E-38 T 12-10-2018 VAPA_1c52540 36da9b03272a1c30073a58509443af52 285 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 19 111 2.6E-14 T 12-10-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal VAPA_1c52540 36da9b03272a1c30073a58509443af52 285 TIGRFAM TIGR00112 proC: pyrroline-5-carboxylate reductase 19 278 5.7E-76 T 12-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 VAPA_1c52540 36da9b03272a1c30073a58509443af52 285 SUPERFAMILY SSF51735 19 171 1.31E-30 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c52540 36da9b03272a1c30073a58509443af52 285 Pfam PF14748 Pyrroline-5-carboxylate reductase dimerisation 174 278 1.3E-33 T 12-10-2018 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 VAPA_1c52540 36da9b03272a1c30073a58509443af52 285 Gene3D G3DSA:3.40.50.720 17 175 3.9E-42 T 12-10-2018 VAPA_1c52540 36da9b03272a1c30073a58509443af52 285 SUPERFAMILY SSF48179 173 282 1.16E-32 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 VAPA_1c52540 36da9b03272a1c30073a58509443af52 285 ProSitePatterns PS00521 Delta 1-pyrroline-5-carboxylate reductase signature. 233 256 - T 12-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 VAPA_1c31340 144b87f7e2bec661e6371c9d08e5a217 333 Gene3D G3DSA:3.30.470.20 178 319 8.5E-32 T 12-10-2018 VAPA_1c31340 144b87f7e2bec661e6371c9d08e5a217 333 PIRSF PIRSF016766 7 331 4.9E-56 T 12-10-2018 IPR024710 Tyramine--L-glutamate ligase KEGG: 00680+6.3.4.24|MetaCyc: PWY-5254 VAPA_1c31340 144b87f7e2bec661e6371c9d08e5a217 333 SUPERFAMILY SSF56059 118 318 1.4E-19 T 12-10-2018 VAPA_1c31340 144b87f7e2bec661e6371c9d08e5a217 333 Pfam PF02655 ATP-grasp domain 131 295 5.0E-24 T 12-10-2018 IPR003806 ATP-grasp fold, DUF201-type GO:0005524|GO:0046872 VAPA_1c20630 a18c0b262423e58344067cc609b5c541 377 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 285 3.4E-42 T 12-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 VAPA_1c20630 a18c0b262423e58344067cc609b5c541 377 PRINTS PR01713 Nucleotide sugar epimerase signature 279 294 1.8E-8 T 12-10-2018 VAPA_1c20630 a18c0b262423e58344067cc609b5c541 377 PRINTS PR01713 Nucleotide sugar epimerase signature 257 272 1.8E-8 T 12-10-2018 VAPA_1c20630 a18c0b262423e58344067cc609b5c541 377 PRINTS PR01713 Nucleotide sugar epimerase signature 319 336 1.8E-8 T 12-10-2018 VAPA_1c20630 a18c0b262423e58344067cc609b5c541 377 Gene3D G3DSA:3.40.50.720 174 340 6.8E-46 T 12-10-2018 VAPA_1c20630 a18c0b262423e58344067cc609b5c541 377 Gene3D G3DSA:3.90.25.10 217 352 6.8E-46 T 12-10-2018 VAPA_1c20630 a18c0b262423e58344067cc609b5c541 377 SUPERFAMILY SSF51735 1 355 4.23E-76 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c20630 a18c0b262423e58344067cc609b5c541 377 Gene3D G3DSA:3.40.50.720 4 139 9.9E-29 T 12-10-2018 VAPA_2c08000 05eb7cc76fa73d1367778117b2d46468 229 Pfam PF00392 Bacterial regulatory proteins, gntR family 20 78 3.0E-19 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_2c08000 05eb7cc76fa73d1367778117b2d46468 229 SMART SM00895 88 210 1.6E-18 T 12-10-2018 IPR011711 GntR, C-terminal VAPA_2c08000 05eb7cc76fa73d1367778117b2d46468 229 Gene3D G3DSA:1.20.120.530 82 218 4.3E-29 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal VAPA_2c08000 05eb7cc76fa73d1367778117b2d46468 229 SUPERFAMILY SSF46785 12 82 2.5E-20 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_2c08000 05eb7cc76fa73d1367778117b2d46468 229 SMART SM00345 20 78 1.9E-17 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_2c08000 05eb7cc76fa73d1367778117b2d46468 229 Gene3D G3DSA:1.10.10.10 13 79 2.1E-23 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_2c08000 05eb7cc76fa73d1367778117b2d46468 229 Pfam PF07729 FCD domain 88 208 5.1E-25 T 12-10-2018 IPR011711 GntR, C-terminal VAPA_2c08000 05eb7cc76fa73d1367778117b2d46468 229 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 52 68 4.4E-6 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_2c08000 05eb7cc76fa73d1367778117b2d46468 229 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 38 52 4.4E-6 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_2c08000 05eb7cc76fa73d1367778117b2d46468 229 SUPERFAMILY SSF48008 84 213 3.14E-26 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal VAPA_2c01030 0d1295e2bf0beb2b5544738f63a9040d 393 PIRSF PIRSF000429 9 386 2.3E-27 T 12-10-2018 IPR002155 Thiolase GO:0016747 VAPA_2c01030 0d1295e2bf0beb2b5544738f63a9040d 393 SUPERFAMILY SSF53901 254 378 1.48E-26 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 VAPA_2c01030 0d1295e2bf0beb2b5544738f63a9040d 393 SUPERFAMILY SSF53901 11 233 2.7E-24 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 VAPA_2c01030 0d1295e2bf0beb2b5544738f63a9040d 393 Pfam PF02803 Thiolase, C-terminal domain 266 375 1.2E-5 T 12-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 VAPA_2c01030 0d1295e2bf0beb2b5544738f63a9040d 393 Gene3D G3DSA:3.40.47.10 6 388 3.4E-117 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 VAPA_2c00260 0a0588756ee72a8889d01f48c7db3bda 297 TIGRFAM TIGR03409 urea_trans_UrtB: urea ABC transporter, permease protein UrtB 4 297 7.1E-98 T 12-10-2018 IPR017779 ABC transporter, urea permease protein UrtB, bacterial-type VAPA_2c00260 0a0588756ee72a8889d01f48c7db3bda 297 Pfam PF02653 Branched-chain amino acid transport system / permease component 6 284 6.3E-43 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 VAPA_1c32620 577001278ce8a645e237bdbc4da075e1 343 SUPERFAMILY SSF51735 14 178 5.91E-8 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c32620 577001278ce8a645e237bdbc4da075e1 343 Gene3D G3DSA:1.10.1040.10 189 328 4.6E-23 T 12-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 VAPA_1c32620 577001278ce8a645e237bdbc4da075e1 343 Pfam PF02558 Ketopantoate reductase PanE/ApbA 14 160 2.1E-26 T 12-10-2018 IPR013332 Ketopantoate reductase, N-terminal domain VAPA_1c32620 577001278ce8a645e237bdbc4da075e1 343 SUPERFAMILY SSF48179 186 323 2.01E-21 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 VAPA_1c32620 577001278ce8a645e237bdbc4da075e1 343 Gene3D G3DSA:3.40.50.720 13 184 1.8E-34 T 12-10-2018 VAPA_1c32620 577001278ce8a645e237bdbc4da075e1 343 TIGRFAM TIGR00745 apbA_panE: 2-dehydropantoate 2-reductase 14 323 1.0E-54 T 12-10-2018 IPR003710 Ketopantoate reductase ApbA/PanE GO:0005737|GO:0008677|GO:0015940 KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654 VAPA_1c32620 577001278ce8a645e237bdbc4da075e1 343 Pfam PF08546 Ketopantoate reductase PanE/ApbA C terminal 187 323 2.3E-21 T 12-10-2018 IPR013752 Ketopantoate reductase, C-terminal domain VAPA_1c39330 6f566f9cb0c13ea96f5a12ae29d9693a 309 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 31 307 2.7E-21 T 12-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 VAPA_1c39330 6f566f9cb0c13ea96f5a12ae29d9693a 309 Gene3D G3DSA:3.40.50.720 6 307 1.5E-92 T 12-10-2018 VAPA_1c39330 6f566f9cb0c13ea96f5a12ae29d9693a 309 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 224 240 - T 12-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site VAPA_1c39330 6f566f9cb0c13ea96f5a12ae29d9693a 309 SUPERFAMILY SSF51735 98 286 2.35E-52 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c39330 6f566f9cb0c13ea96f5a12ae29d9693a 309 Gene3D G3DSA:3.40.50.720 98 283 1.5E-92 T 12-10-2018 VAPA_1c39330 6f566f9cb0c13ea96f5a12ae29d9693a 309 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 108 285 2.7E-53 T 12-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 VAPA_1c39330 6f566f9cb0c13ea96f5a12ae29d9693a 309 SUPERFAMILY SSF52283 1 133 5.32E-26 T 12-10-2018 VAPA_1c28370 219897cf39283589adafe50e46cc9951 660 SUPERFAMILY SSF140990 437 610 8.11E-25 T 12-10-2018 IPR037219 Peptidase M41-like GO:0004222|GO:0005524|GO:0006508 Reactome: R-HSA-8949664 VAPA_1c28370 219897cf39283589adafe50e46cc9951 660 Gene3D G3DSA:3.40.50.300 13 164 5.9E-12 T 12-10-2018 VAPA_1c28370 219897cf39283589adafe50e46cc9951 660 SMART SM00382 57 279 1.2E-5 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c28370 219897cf39283589adafe50e46cc9951 660 Gene3D G3DSA:1.20.58.760 429 614 6.5E-33 T 12-10-2018 VAPA_1c28370 219897cf39283589adafe50e46cc9951 660 SUPERFAMILY SSF52540 24 378 1.21E-15 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c28370 219897cf39283589adafe50e46cc9951 660 Pfam PF01434 Peptidase family M41 436 604 1.2E-18 T 12-10-2018 IPR000642 Peptidase M41 GO:0004222|GO:0005524|GO:0006508 Reactome: R-HSA-8949664 VAPA_1c28370 219897cf39283589adafe50e46cc9951 660 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 61 137 2.0E-6 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 VAPA_1c48770 246aebfdad57a6ea93c6180628d393f2 556 Gene3D G3DSA:3.40.50.12780 7 441 5.7E-121 T 12-10-2018 VAPA_1c48770 246aebfdad57a6ea93c6180628d393f2 556 Gene3D G3DSA:3.30.300.30 444 549 2.1E-33 T 12-10-2018 VAPA_1c48770 246aebfdad57a6ea93c6180628d393f2 556 Pfam PF00501 AMP-binding enzyme 25 450 2.6E-109 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 VAPA_1c48770 246aebfdad57a6ea93c6180628d393f2 556 Pfam PF13193 AMP-binding enzyme C-terminal domain 459 534 2.1E-19 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain VAPA_1c48770 246aebfdad57a6ea93c6180628d393f2 556 ProSitePatterns PS00455 Putative AMP-binding domain signature. 199 210 - T 12-10-2018 IPR020845 AMP-binding, conserved site VAPA_1c48770 246aebfdad57a6ea93c6180628d393f2 556 SUPERFAMILY SSF56801 14 546 2.22E-160 T 12-10-2018 VAPA_1c27570 396cb59e142667c65569d76420422d1a 369 Gene3D G3DSA:3.40.50.1820 170 364 3.0E-25 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c27570 396cb59e142667c65569d76420422d1a 369 Pfam PF12697 Alpha/beta hydrolase family 219 339 4.6E-6 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 VAPA_1c27570 396cb59e142667c65569d76420422d1a 369 Pfam PF14437 MafB19-like deaminase 10 157 2.3E-29 T 12-10-2018 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 VAPA_1c27570 396cb59e142667c65569d76420422d1a 369 SUPERFAMILY SSF53927 8 157 9.2E-56 T 12-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 VAPA_1c27570 396cb59e142667c65569d76420422d1a 369 Hamap MF_00972 tRNA-specific adenosine deaminase [tadA]. 16 157 47.919 T 12-10-2018 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 VAPA_1c27570 396cb59e142667c65569d76420422d1a 369 SUPERFAMILY SSF53474 175 286 3.21E-16 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c27570 396cb59e142667c65569d76420422d1a 369 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 61 98 - T 12-10-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 VAPA_1c27570 396cb59e142667c65569d76420422d1a 369 Gene3D G3DSA:3.40.140.10 6 169 1.4E-62 T 12-10-2018 VAPA_1c44980 e9c77fed1a98a33f0df230fec943bece 751 TIGRFAM TIGR00691 spoT_relA: RelA/SpoT family protein 51 743 3.9E-212 T 12-10-2018 IPR004811 RelA/SpoT family GO:0015969 VAPA_1c44980 e9c77fed1a98a33f0df230fec943bece 751 Gene3D G3DSA:3.10.20.30 406 478 1.2E-29 T 12-10-2018 IPR012675 Beta-grasp domain superfamily VAPA_1c44980 e9c77fed1a98a33f0df230fec943bece 751 SUPERFAMILY SSF81271 400 472 3.71E-21 T 12-10-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 VAPA_1c44980 e9c77fed1a98a33f0df230fec943bece 751 SMART SM00471 66 178 3.4E-10 T 12-10-2018 IPR003607 HD/PDEase domain VAPA_1c44980 e9c77fed1a98a33f0df230fec943bece 751 Pfam PF13291 ACT domain 669 746 1.1E-12 T 12-10-2018 IPR002912 ACT domain VAPA_1c44980 e9c77fed1a98a33f0df230fec943bece 751 Pfam PF13328 HD domain 51 200 1.4E-50 T 12-10-2018 IPR003607 HD/PDEase domain VAPA_1c44980 e9c77fed1a98a33f0df230fec943bece 751 SMART SM00954 260 370 1.3E-56 T 12-10-2018 IPR007685 RelA/SpoT GO:0015969 VAPA_1c44980 e9c77fed1a98a33f0df230fec943bece 751 Pfam PF04607 Region found in RelA / SpoT proteins 260 369 2.5E-30 T 12-10-2018 IPR007685 RelA/SpoT GO:0015969 VAPA_1c44980 e9c77fed1a98a33f0df230fec943bece 751 Gene3D G3DSA:3.30.460.10 218 350 2.1E-39 T 12-10-2018 VAPA_1c44980 e9c77fed1a98a33f0df230fec943bece 751 Gene3D G3DSA:1.10.3210.10 26 216 3.6E-76 T 12-10-2018 VAPA_1c44980 e9c77fed1a98a33f0df230fec943bece 751 Pfam PF02824 TGS domain 413 472 1.5E-20 T 12-10-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 VAPA_1c44980 e9c77fed1a98a33f0df230fec943bece 751 SUPERFAMILY SSF81301 206 417 3.92E-54 T 12-10-2018 VAPA_1c44980 e9c77fed1a98a33f0df230fec943bece 751 SUPERFAMILY SSF109604 35 215 1.41E-71 T 12-10-2018 VAPA_1c44980 e9c77fed1a98a33f0df230fec943bece 751 Gene3D G3DSA:3.30.70.260 669 748 1.4E-7 T 12-10-2018 VAPA_1c35170 21d2c1741affc9abc820cdfebf9dabe4 260 ProSitePatterns PS00211 ABC transporters family signature. 144 158 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_1c35170 21d2c1741affc9abc820cdfebf9dabe4 260 SUPERFAMILY SSF52540 29 226 8.18E-63 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c35170 21d2c1741affc9abc820cdfebf9dabe4 260 SMART SM00382 39 234 9.3E-18 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c35170 21d2c1741affc9abc820cdfebf9dabe4 260 Pfam PF00005 ABC transporter 31 171 1.3E-29 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c35170 21d2c1741affc9abc820cdfebf9dabe4 260 Gene3D G3DSA:3.40.50.300 10 256 5.2E-58 T 12-10-2018 VAPA_1c49670 31d53945a9b50daf2a6678f3c9d33fb0 552 Pfam PF06974 Protein of unknown function (DUF1298) 316 460 7.3E-28 T 12-10-2018 IPR009721 O-acyltransferase WSD1, C-terminal GO:0004144 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 VAPA_1c49670 31d53945a9b50daf2a6678f3c9d33fb0 552 SUPERFAMILY SSF52777 69 158 4.3E-5 T 12-10-2018 VAPA_1c49670 31d53945a9b50daf2a6678f3c9d33fb0 552 Pfam PF03007 Wax ester synthase-like Acyl-CoA acyltransferase domain 4 275 1.7E-68 T 12-10-2018 IPR004255 O-acyltransferase, WSD1, N-terminal GO:0004144|GO:0045017 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 VAPA_1c49670 31d53945a9b50daf2a6678f3c9d33fb0 552 TIGRFAM TIGR02946 acyl_WS_DGAT: acyltransferase, WS/DGAT/MGAT 4 466 5.4E-136 T 12-10-2018 IPR014292 Acyltransferase, WS/DGAT/MGAT GO:0016746|GO:0045017 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 VAPA_1c16400 6718f2832068a44e468ff7ba9e84203c 406 SUPERFAMILY SSF51905 1 402 5.18E-44 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c16400 6718f2832068a44e468ff7ba9e84203c 406 Gene3D G3DSA:3.50.50.60 95 401 2.2E-50 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c16400 6718f2832068a44e468ff7ba9e84203c 406 Gene3D G3DSA:3.50.50.60 3 50 3.7E-15 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c16400 6718f2832068a44e468ff7ba9e84203c 406 Gene3D G3DSA:3.30.9.10 133 359 2.2E-50 T 12-10-2018 VAPA_1c16400 6718f2832068a44e468ff7ba9e84203c 406 SUPERFAMILY SSF54373 269 360 1.07E-13 T 12-10-2018 VAPA_1c16400 6718f2832068a44e468ff7ba9e84203c 406 Pfam PF01266 FAD dependent oxidoreductase 2 399 8.8E-64 T 12-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 VAPA_1c42160 b2fea7375b4971575c2bf2426a9db1b9 205 SUPERFAMILY SSF89155 12 203 6.67E-49 T 12-10-2018 IPR036411 TorD-like superfamily VAPA_1c42160 b2fea7375b4971575c2bf2426a9db1b9 205 Gene3D G3DSA:1.10.3480.10 7 202 5.8E-39 T 12-10-2018 VAPA_1c42160 b2fea7375b4971575c2bf2426a9db1b9 205 Pfam PF02613 Nitrate reductase delta subunit 51 171 1.4E-26 T 12-10-2018 IPR020945 DMSO/Nitrate reductase chaperone VAPA_1c35050 83d73cf5d6d40d7dc07a50e0fb14fffb 361 PRINTS PR00344 Bacterial sensor protein C-terminal signature 299 313 6.2E-7 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c35050 83d73cf5d6d40d7dc07a50e0fb14fffb 361 PRINTS PR00344 Bacterial sensor protein C-terminal signature 316 334 6.2E-7 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c35050 83d73cf5d6d40d7dc07a50e0fb14fffb 361 PRINTS PR00344 Bacterial sensor protein C-terminal signature 340 353 6.2E-7 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c35050 83d73cf5d6d40d7dc07a50e0fb14fffb 361 SUPERFAMILY SSF55785 24 132 1.5E-21 T 12-10-2018 IPR035965 PAS domain superfamily VAPA_1c35050 83d73cf5d6d40d7dc07a50e0fb14fffb 361 Pfam PF07730 Histidine kinase 161 225 2.2E-9 T 12-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 VAPA_1c35050 83d73cf5d6d40d7dc07a50e0fb14fffb 361 SUPERFAMILY SSF55874 230 354 2.49E-20 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_1c35050 83d73cf5d6d40d7dc07a50e0fb14fffb 361 Gene3D G3DSA:3.30.565.10 228 355 3.7E-32 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_1c35050 83d73cf5d6d40d7dc07a50e0fb14fffb 361 Pfam PF08448 PAS fold 27 134 2.0E-11 T 12-10-2018 IPR013656 PAS fold-4 VAPA_1c35050 83d73cf5d6d40d7dc07a50e0fb14fffb 361 SMART SM00387 263 356 2.4E-8 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase VAPA_1c35050 83d73cf5d6d40d7dc07a50e0fb14fffb 361 Gene3D G3DSA:3.30.450.20 23 150 1.1E-21 T 12-10-2018 VAPA_1c35050 83d73cf5d6d40d7dc07a50e0fb14fffb 361 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 22 138 1.9E-24 T 12-10-2018 IPR000014 PAS domain VAPA_1c35050 83d73cf5d6d40d7dc07a50e0fb14fffb 361 SMART SM00091 20 85 5.0E-8 T 12-10-2018 IPR000014 PAS domain VAPA_1c35050 83d73cf5d6d40d7dc07a50e0fb14fffb 361 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 267 355 5.6E-8 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase VAPA_1c18080 ce5b0df8332453ccc8d8ca610674cb88 253 Gene3D G3DSA:3.40.50.720 1 252 1.6E-79 T 12-10-2018 VAPA_1c18080 ce5b0df8332453ccc8d8ca610674cb88 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 158 177 2.7E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c18080 ce5b0df8332453ccc8d8ca610674cb88 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 2.7E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c18080 ce5b0df8332453ccc8d8ca610674cb88 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 137 145 2.7E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c18080 ce5b0df8332453ccc8d8ca610674cb88 253 SUPERFAMILY SSF51735 5 252 3.1E-77 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c18080 ce5b0df8332453ccc8d8ca610674cb88 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 2.2E-41 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c18080 ce5b0df8332453ccc8d8ca610674cb88 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 2.2E-41 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c18080 ce5b0df8332453ccc8d8ca610674cb88 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 213 233 2.2E-41 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c18080 ce5b0df8332453ccc8d8ca610674cb88 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 2.2E-41 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c18080 ce5b0df8332453ccc8d8ca610674cb88 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 2.2E-41 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c18080 ce5b0df8332453ccc8d8ca610674cb88 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 2.2E-41 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c18080 ce5b0df8332453ccc8d8ca610674cb88 253 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 249 1.7E-61 T 12-10-2018 VAPA_1c18080 ce5b0df8332453ccc8d8ca610674cb88 253 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 223 0.0027 T 12-10-2018 VAPA_1c25520 83b6f858b3ef105edc08dcbdf13d0231 357 SUPERFAMILY SSF56266 12 336 1.28E-103 T 12-10-2018 IPR016117 ArgJ-like domain superfamily KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 VAPA_1c25520 83b6f858b3ef105edc08dcbdf13d0231 357 Gene3D G3DSA:3.60.70.12 6 344 1.9E-126 T 12-10-2018 IPR016117 ArgJ-like domain superfamily KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 VAPA_1c25520 83b6f858b3ef105edc08dcbdf13d0231 357 Pfam PF03576 Peptidase family S58 18 334 1.5E-114 T 12-10-2018 IPR005321 Peptidase S58, DmpA VAPA_1c40740 dcdb81833f23738b0c4345a5ce36b27b 245 Pfam PF01177 Asp/Glu/Hydantoin racemase 5 205 1.5E-15 T 12-10-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 VAPA_1c40740 dcdb81833f23738b0c4345a5ce36b27b 245 Gene3D G3DSA:3.40.50.12500 1 243 1.9E-93 T 12-10-2018 VAPA_1c50090 bb315e843ce364378c0dba6117b4fb20 263 Hamap MF_00830 Peroxyureidoacrylate/ureidoacrylate amidohydrolase RutB [rutB]. 27 254 58.553 T 12-10-2018 IPR019916 Isochorismatase, RutB GO:0016811 KEGG: 00240+3.5.1.110 VAPA_1c50090 bb315e843ce364378c0dba6117b4fb20 263 SUPERFAMILY SSF52499 26 245 9.03E-54 T 12-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 VAPA_1c50090 bb315e843ce364378c0dba6117b4fb20 263 Pfam PF00857 Isochorismatase family 44 242 6.9E-41 T 12-10-2018 IPR000868 Isochorismatase-like GO:0003824 VAPA_1c50090 bb315e843ce364378c0dba6117b4fb20 263 TIGRFAM TIGR03614 RutB: pyrimidine utilization protein B 29 251 2.5E-122 T 12-10-2018 IPR019916 Isochorismatase, RutB GO:0016811 KEGG: 00240+3.5.1.110 VAPA_1c50090 bb315e843ce364378c0dba6117b4fb20 263 Gene3D G3DSA:3.40.50.850 35 259 1.5E-56 T 12-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 VAPA_2c05690 b20232b88aa14fa86da88a01b49830a0 181 SUPERFAMILY SSF54427 11 143 4.29E-34 T 12-10-2018 IPR032710 NTF2-like domain superfamily VAPA_2c05690 b20232b88aa14fa86da88a01b49830a0 181 Pfam PF13577 SnoaL-like domain 12 134 1.3E-21 T 12-10-2018 IPR037401 SnoaL-like domain VAPA_2c05690 b20232b88aa14fa86da88a01b49830a0 181 Gene3D G3DSA:3.10.450.50 14 151 9.0E-37 T 12-10-2018 VAPA_1c47490 eaf008d382b9a81c21177eb79d1d4a4c 315 Pfam PF12833 Helix-turn-helix domain 234 303 9.3E-16 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 VAPA_1c47490 eaf008d382b9a81c21177eb79d1d4a4c 315 SMART SM00342 230 302 5.7E-18 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 VAPA_1c47490 eaf008d382b9a81c21177eb79d1d4a4c 315 SUPERFAMILY SSF51182 41 87 7.69E-5 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily VAPA_1c47490 eaf008d382b9a81c21177eb79d1d4a4c 315 SUPERFAMILY SSF46689 255 305 2.02E-11 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 VAPA_1c47490 eaf008d382b9a81c21177eb79d1d4a4c 315 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 286 302 2.2E-5 T 12-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 VAPA_1c47490 eaf008d382b9a81c21177eb79d1d4a4c 315 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 271 286 2.2E-5 T 12-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 VAPA_1c47490 eaf008d382b9a81c21177eb79d1d4a4c 315 Gene3D G3DSA:1.10.10.60 220 307 8.3E-17 T 12-10-2018 VAPA_1c47490 eaf008d382b9a81c21177eb79d1d4a4c 315 Pfam PF12852 Cupin 2 197 2.1E-38 T 12-10-2018 IPR032783 AraC-type transcription regulator, ligand-binding domain VAPA_1c47490 eaf008d382b9a81c21177eb79d1d4a4c 315 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 256 298 - T 12-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 VAPA_1c53990 92d955f36850b91ba242fb507b8096cd 297 Pfam PF00549 CoA-ligase 160 271 1.4E-15 T 12-10-2018 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 VAPA_1c53990 92d955f36850b91ba242fb507b8096cd 297 ProSitePatterns PS00399 ATP-citrate lyase / succinyl-CoA ligases family active site. 245 258 - T 12-10-2018 IPR017440 ATP-citrate lyase/succinyl-CoA ligase, active site VAPA_1c53990 92d955f36850b91ba242fb507b8096cd 297 Pfam PF02629 CoA binding domain 6 102 6.4E-21 T 12-10-2018 IPR003781 CoA-binding GO:0048037 VAPA_1c53990 92d955f36850b91ba242fb507b8096cd 297 SMART SM00881 4 103 1.1E-24 T 12-10-2018 IPR003781 CoA-binding GO:0048037 VAPA_1c53990 92d955f36850b91ba242fb507b8096cd 297 Hamap MF_01988 Succinate--CoA ligase [ADP-forming] subunit alpha [sucD]. 1 297 39.237 T 12-10-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 VAPA_1c53990 92d955f36850b91ba242fb507b8096cd 297 PRINTS PR01798 Succinyl-CoA synthase signature 186 204 2.6E-32 T 12-10-2018 VAPA_1c53990 92d955f36850b91ba242fb507b8096cd 297 PRINTS PR01798 Succinyl-CoA synthase signature 249 266 2.6E-32 T 12-10-2018 VAPA_1c53990 92d955f36850b91ba242fb507b8096cd 297 PRINTS PR01798 Succinyl-CoA synthase signature 85 102 2.6E-32 T 12-10-2018 VAPA_1c53990 92d955f36850b91ba242fb507b8096cd 297 PRINTS PR01798 Succinyl-CoA synthase signature 217 230 2.6E-32 T 12-10-2018 VAPA_1c53990 92d955f36850b91ba242fb507b8096cd 297 PIRSF PIRSF001553 1 297 4.4E-113 T 12-10-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 VAPA_1c53990 92d955f36850b91ba242fb507b8096cd 297 ProSitePatterns PS01216 ATP-citrate lyase / succinyl-CoA ligases family signature 1. 161 190 - T 12-10-2018 IPR033847 ATP-citrate lyase/succinyl-CoA ligase, conserved site VAPA_1c53990 92d955f36850b91ba242fb507b8096cd 297 TIGRFAM TIGR01019 sucCoAalpha: succinate-CoA ligase, alpha subunit 3 297 5.4E-123 T 12-10-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 VAPA_1c53990 92d955f36850b91ba242fb507b8096cd 297 Gene3D G3DSA:3.40.50.720 2 132 2.3E-40 T 12-10-2018 VAPA_1c53990 92d955f36850b91ba242fb507b8096cd 297 Gene3D G3DSA:3.40.50.261 133 297 2.4E-66 T 12-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 VAPA_1c53990 92d955f36850b91ba242fb507b8096cd 297 SUPERFAMILY SSF51735 1 118 1.02E-33 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c53990 92d955f36850b91ba242fb507b8096cd 297 SUPERFAMILY SSF52210 132 295 3.27E-52 T 12-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 VAPA_2c10800 aa518c1c4bc6ef40e8762bdd7305b18c 409 Pfam PF02515 CoA-transferase family III 8 385 1.8E-134 T 12-10-2018 IPR003673 CoA-transferase family III GO:0003824 VAPA_2c10800 aa518c1c4bc6ef40e8762bdd7305b18c 409 SUPERFAMILY SSF89796 6 409 2.75E-144 T 12-10-2018 IPR023606 CoA-transferase family III domain superfamily VAPA_2c10800 aa518c1c4bc6ef40e8762bdd7305b18c 409 Gene3D G3DSA:3.30.1540.10 246 337 5.2E-144 T 12-10-2018 VAPA_2c10800 aa518c1c4bc6ef40e8762bdd7305b18c 409 Gene3D G3DSA:3.40.50.10540 7 403 5.2E-144 T 12-10-2018 IPR023606 CoA-transferase family III domain superfamily VAPA_1c32320 eb85e7a8f9fccc6f12278b35c6955e31 421 TIGRFAM TIGR03407 urea_ABC_UrtA: urea ABC transporter, urea binding protein 58 416 1.7E-156 T 12-10-2018 IPR017777 Urea ABC transporter, substrate-binding protein UrtA-like VAPA_1c32320 eb85e7a8f9fccc6f12278b35c6955e31 421 SUPERFAMILY SSF53822 57 417 4.04E-91 T 12-10-2018 IPR028082 Periplasmic binding protein-like I VAPA_1c32320 eb85e7a8f9fccc6f12278b35c6955e31 421 Pfam PF13433 Periplasmic binding protein domain 59 418 2.7E-126 T 12-10-2018 VAPA_1c32320 eb85e7a8f9fccc6f12278b35c6955e31 421 Gene3D G3DSA:3.40.50.2300 60 388 1.9E-127 T 12-10-2018 VAPA_1c32320 eb85e7a8f9fccc6f12278b35c6955e31 421 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 80 96 7.7E-6 T 12-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 VAPA_1c32320 eb85e7a8f9fccc6f12278b35c6955e31 421 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 121 131 7.7E-6 T 12-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 VAPA_1c32320 eb85e7a8f9fccc6f12278b35c6955e31 421 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 311 324 7.7E-6 T 12-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 VAPA_1c32320 eb85e7a8f9fccc6f12278b35c6955e31 421 Gene3D G3DSA:3.40.50.2300 173 407 1.9E-127 T 12-10-2018 VAPA_1c51370 c815bb6328d09b673e4c001b751ea5a4 452 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 7 318 1.1E-70 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 VAPA_1c51370 c815bb6328d09b673e4c001b751ea5a4 452 SUPERFAMILY SSF55424 335 448 6.87E-35 T 12-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 VAPA_1c51370 c815bb6328d09b673e4c001b751ea5a4 452 Gene3D G3DSA:3.50.50.60 145 261 4.2E-116 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c51370 c815bb6328d09b673e4c001b751ea5a4 452 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 338 446 1.3E-34 T 12-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 VAPA_1c51370 c815bb6328d09b673e4c001b751ea5a4 452 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 255 269 4.1E-72 T 12-10-2018 VAPA_1c51370 c815bb6328d09b673e4c001b751ea5a4 452 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 298 305 4.1E-72 T 12-10-2018 VAPA_1c51370 c815bb6328d09b673e4c001b751ea5a4 452 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 334 355 4.1E-72 T 12-10-2018 VAPA_1c51370 c815bb6328d09b673e4c001b751ea5a4 452 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 136 145 4.1E-72 T 12-10-2018 VAPA_1c51370 c815bb6328d09b673e4c001b751ea5a4 452 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 399 414 4.1E-72 T 12-10-2018 VAPA_1c51370 c815bb6328d09b673e4c001b751ea5a4 452 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 170 195 4.1E-72 T 12-10-2018 VAPA_1c51370 c815bb6328d09b673e4c001b751ea5a4 452 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 39 54 4.1E-72 T 12-10-2018 VAPA_1c51370 c815bb6328d09b673e4c001b751ea5a4 452 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 421 441 4.1E-72 T 12-10-2018 VAPA_1c51370 c815bb6328d09b673e4c001b751ea5a4 452 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 7 29 4.1E-72 T 12-10-2018 VAPA_1c51370 c815bb6328d09b673e4c001b751ea5a4 452 Gene3D G3DSA:3.30.390.30 337 451 2.2E-45 T 12-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 VAPA_1c51370 c815bb6328d09b673e4c001b751ea5a4 452 PIRSF PIRSF000350 2 441 4.3E-88 T 12-10-2018 IPR001100 Pyridine nucleotide-disulphide oxidoreductase, class I GO:0009055|GO:0016491 VAPA_1c51370 c815bb6328d09b673e4c001b751ea5a4 452 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 8 27 1.5E-33 T 12-10-2018 VAPA_1c51370 c815bb6328d09b673e4c001b751ea5a4 452 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 133 151 1.5E-33 T 12-10-2018 VAPA_1c51370 c815bb6328d09b673e4c001b751ea5a4 452 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 283 305 1.5E-33 T 12-10-2018 VAPA_1c51370 c815bb6328d09b673e4c001b751ea5a4 452 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 254 270 1.5E-33 T 12-10-2018 VAPA_1c51370 c815bb6328d09b673e4c001b751ea5a4 452 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 170 188 1.5E-33 T 12-10-2018 VAPA_1c51370 c815bb6328d09b673e4c001b751ea5a4 452 SUPERFAMILY SSF51905 3 365 6.91E-68 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c51370 c815bb6328d09b673e4c001b751ea5a4 452 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 40 50 - T 12-10-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 VAPA_1c51370 c815bb6328d09b673e4c001b751ea5a4 452 Gene3D G3DSA:3.50.50.60 6 321 4.2E-116 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_2c04660 79259fda25f218a1b040cb4a29e6e9ca 140 SUPERFAMILY SSF49764 14 139 2.79E-30 T 12-10-2018 IPR008978 HSP20-like chaperone VAPA_2c04660 79259fda25f218a1b040cb4a29e6e9ca 140 Gene3D G3DSA:2.60.40.790 2 140 2.6E-30 T 12-10-2018 IPR008978 HSP20-like chaperone VAPA_2c04660 79259fda25f218a1b040cb4a29e6e9ca 140 Pfam PF00011 Hsp20/alpha crystallin family 40 134 1.2E-17 T 12-10-2018 IPR002068 Alpha crystallin/Hsp20 domain VAPA_1c45410 4982ffe8d8275bcbd32f6148d4da977b 167 SUPERFAMILY SSF52374 6 157 1.13E-40 T 12-10-2018 VAPA_1c45410 4982ffe8d8275bcbd32f6148d4da977b 167 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 6 61 1.9E-15 T 12-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 VAPA_1c45410 4982ffe8d8275bcbd32f6148d4da977b 167 Gene3D G3DSA:3.40.50.620 1 163 6.1E-53 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold VAPA_1c45410 4982ffe8d8275bcbd32f6148d4da977b 167 Hamap MF_00151 Phosphopantetheine adenylyltransferase [coaD]. 5 162 33.155 T 12-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 VAPA_1c45410 4982ffe8d8275bcbd32f6148d4da977b 167 Pfam PF01467 Cytidylyltransferase-like 8 137 9.1E-20 T 12-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 VAPA_1c45410 4982ffe8d8275bcbd32f6148d4da977b 167 TIGRFAM TIGR01510 coaD_prev_kdtB: pantetheine-phosphate adenylyltransferase 6 160 1.0E-53 T 12-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 VAPA_1c45410 4982ffe8d8275bcbd32f6148d4da977b 167 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 89 105 2.9E-37 T 12-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 VAPA_1c45410 4982ffe8d8275bcbd32f6148d4da977b 167 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 52 76 2.9E-37 T 12-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 VAPA_1c45410 4982ffe8d8275bcbd32f6148d4da977b 167 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 116 138 2.9E-37 T 12-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 VAPA_1c45410 4982ffe8d8275bcbd32f6148d4da977b 167 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 5 23 2.9E-37 T 12-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 VAPA_1c45410 4982ffe8d8275bcbd32f6148d4da977b 167 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 23 44 2.9E-37 T 12-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 VAPA_1c28080 9c72224cc5208fe503d4654a3d5fdafb 318 SUPERFAMILY SSF55120 12 239 6.62E-80 T 12-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 VAPA_1c28080 9c72224cc5208fe503d4654a3d5fdafb 318 Pfam PF16198 tRNA pseudouridylate synthase B C-terminal domain 183 240 1.1E-16 T 12-10-2018 IPR032819 tRNA pseudouridylate synthase B, C-terminal Reactome: R-HSA-171319|Reactome: R-HSA-6790901 VAPA_1c28080 9c72224cc5208fe503d4654a3d5fdafb 318 Pfam PF09157 Pseudouridine synthase II TruB, C-terminal 245 299 7.9E-5 T 12-10-2018 IPR015240 tRNA pseudouridine synthase II, TruB, subfamily 1, C-terminal GO:0001522|GO:0003723|GO:0009451|GO:0009982 VAPA_1c28080 9c72224cc5208fe503d4654a3d5fdafb 318 Hamap MF_01080 tRNA pseudouridine synthase B [truB]. 13 299 17.971 T 12-10-2018 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 VAPA_1c28080 9c72224cc5208fe503d4654a3d5fdafb 318 Gene3D G3DSA:3.30.2350.10 4 249 1.2E-87 T 12-10-2018 VAPA_1c28080 9c72224cc5208fe503d4654a3d5fdafb 318 TIGRFAM TIGR00431 TruB: tRNA pseudouridine(55) synthase 14 221 9.4E-71 T 12-10-2018 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 VAPA_1c28080 9c72224cc5208fe503d4654a3d5fdafb 318 Pfam PF01509 TruB family pseudouridylate synthase (N terminal domain) 35 182 3.7E-54 T 12-10-2018 IPR002501 Pseudouridine synthase II, N-terminal GO:0006396 VAPA_1c53110 e499a2388e211d45d2d41586e7d712ba 111 SMART SM01323 22 104 4.4E-43 T 12-10-2018 IPR003849 Preprotein translocase YajC VAPA_1c53110 e499a2388e211d45d2d41586e7d712ba 111 Pfam PF02699 Preprotein translocase subunit 26 101 4.0E-29 T 12-10-2018 IPR003849 Preprotein translocase YajC VAPA_1c53110 e499a2388e211d45d2d41586e7d712ba 111 PRINTS PR01853 Bacterial YajC preprotein translocase signature 62 80 3.5E-15 T 12-10-2018 IPR003849 Preprotein translocase YajC VAPA_1c53110 e499a2388e211d45d2d41586e7d712ba 111 PRINTS PR01853 Bacterial YajC preprotein translocase signature 24 44 3.5E-15 T 12-10-2018 IPR003849 Preprotein translocase YajC VAPA_1c53110 e499a2388e211d45d2d41586e7d712ba 111 TIGRFAM TIGR00739 yajC: preprotein translocase, YajC subunit 23 104 5.6E-27 T 12-10-2018 IPR003849 Preprotein translocase YajC VAPA_2c06580 fcda3e3a943a022e8d9fdc9ad1815e91 448 Gene3D G3DSA:1.10.3860.10 5 424 1.8E-120 T 12-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 VAPA_2c06580 fcda3e3a943a022e8d9fdc9ad1815e91 448 ProSitePatterns PS00713 Sodium:dicarboxylate symporter family signature 1. 42 57 - T 12-10-2018 IPR018107 Sodium:dicarboxylate symporter, conserved site VAPA_2c06580 fcda3e3a943a022e8d9fdc9ad1815e91 448 SUPERFAMILY SSF118215 15 407 2.35E-120 T 12-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 VAPA_2c06580 fcda3e3a943a022e8d9fdc9ad1815e91 448 Hamap MF_01300 C4-dicarboxylate transport protein [dctA]. 8 434 38.303 T 12-10-2018 IPR023954 C4-dicarboxylate transport protein GO:0006835|GO:0015293|GO:0016021 VAPA_2c06580 fcda3e3a943a022e8d9fdc9ad1815e91 448 PRINTS PR00173 Glutamate-aspartate symporter signature 333 352 1.2E-30 T 12-10-2018 VAPA_2c06580 fcda3e3a943a022e8d9fdc9ad1815e91 448 PRINTS PR00173 Glutamate-aspartate symporter signature 80 105 1.2E-30 T 12-10-2018 VAPA_2c06580 fcda3e3a943a022e8d9fdc9ad1815e91 448 PRINTS PR00173 Glutamate-aspartate symporter signature 298 324 1.2E-30 T 12-10-2018 VAPA_2c06580 fcda3e3a943a022e8d9fdc9ad1815e91 448 PRINTS PR00173 Glutamate-aspartate symporter signature 9 29 1.2E-30 T 12-10-2018 VAPA_2c06580 fcda3e3a943a022e8d9fdc9ad1815e91 448 PRINTS PR00173 Glutamate-aspartate symporter signature 151 173 1.2E-30 T 12-10-2018 VAPA_2c06580 fcda3e3a943a022e8d9fdc9ad1815e91 448 PRINTS PR00173 Glutamate-aspartate symporter signature 50 70 1.2E-30 T 12-10-2018 VAPA_2c06580 fcda3e3a943a022e8d9fdc9ad1815e91 448 Pfam PF00375 Sodium:dicarboxylate symporter family 15 407 7.8E-109 T 12-10-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 VAPA_2c06580 fcda3e3a943a022e8d9fdc9ad1815e91 448 ProSitePatterns PS00714 Sodium:dicarboxylate symporter family signature 2. 301 324 - T 12-10-2018 IPR018107 Sodium:dicarboxylate symporter, conserved site VAPA_1c03470 299f772a88ca815f41d3d48930866a44 322 Gene3D G3DSA:2.40.10.350 189 268 2.4E-30 T 12-10-2018 VAPA_1c03470 299f772a88ca815f41d3d48930866a44 322 Gene3D G3DSA:2.40.10.340 130 279 2.4E-30 T 12-10-2018 VAPA_1c03470 299f772a88ca815f41d3d48930866a44 322 Pfam PF04085 rod shape-determining protein MreC 132 280 4.0E-36 T 12-10-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 VAPA_1c03470 299f772a88ca815f41d3d48930866a44 322 TIGRFAM TIGR00219 mreC: rod shape-determining protein MreC 14 282 3.2E-44 T 12-10-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 VAPA_1c03470 299f772a88ca815f41d3d48930866a44 322 PIRSF PIRSF038471 11 295 8.2E-68 T 12-10-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 VAPA_1c52440 ced2bd4e5546ad66204b665d00627c5b 61 Pfam PF00327 Ribosomal protein L30p/L7e 8 58 8.7E-18 T 12-10-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain VAPA_1c52440 ced2bd4e5546ad66204b665d00627c5b 61 SUPERFAMILY SSF55129 6 60 2.09E-19 T 12-10-2018 IPR036919 Ribosomal protein L30, ferredoxin-like fold domain superfamily VAPA_1c52440 ced2bd4e5546ad66204b665d00627c5b 61 Gene3D G3DSA:3.30.1390.20 4 61 1.1E-24 T 12-10-2018 IPR036919 Ribosomal protein L30, ferredoxin-like fold domain superfamily VAPA_1c52440 ced2bd4e5546ad66204b665d00627c5b 61 TIGRFAM TIGR01308 rpmD_bact: ribosomal protein uL30 8 60 1.1E-23 T 12-10-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 VAPA_1c52440 ced2bd4e5546ad66204b665d00627c5b 61 PIRSF PIRSF002211 1 61 3.3E-25 T 12-10-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 VAPA_1c52440 ced2bd4e5546ad66204b665d00627c5b 61 Hamap MF_01371_B 50S ribosomal protein L30 [rpmD]. 5 61 17.27 T 12-10-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 VAPA_1c47670 a24dfd9e222596570dce5528ad400559 56 ProSitePatterns PS00202 Rubredoxin signature. 35 45 - T 12-10-2018 IPR018527 Rubredoxin, iron-binding site GO:0046872 VAPA_1c47670 a24dfd9e222596570dce5528ad400559 56 PIRSF PIRSF000071 1 56 4.7E-26 T 12-10-2018 IPR024922 Rubredoxin GO:0005506|GO:0009055 VAPA_1c47670 a24dfd9e222596570dce5528ad400559 56 PRINTS PR00163 Rubredoxin signature 35 51 2.9E-8 T 12-10-2018 IPR024935 Rubredoxin domain GO:0005506 VAPA_1c47670 a24dfd9e222596570dce5528ad400559 56 PRINTS PR00163 Rubredoxin signature 5 21 2.9E-8 T 12-10-2018 IPR024935 Rubredoxin domain GO:0005506 VAPA_1c47670 a24dfd9e222596570dce5528ad400559 56 Gene3D G3DSA:2.20.28.10 1 56 1.7E-27 T 12-10-2018 VAPA_1c47670 a24dfd9e222596570dce5528ad400559 56 Pfam PF00301 Rubredoxin 6 51 8.2E-22 T 12-10-2018 IPR024935 Rubredoxin domain GO:0005506 VAPA_1c47670 a24dfd9e222596570dce5528ad400559 56 SUPERFAMILY SSF57802 2 55 2.86E-22 T 12-10-2018 VAPA_1c27100 20658859d97faf738e67d97f65032d9c 578 Gene3D G3DSA:1.10.510.10 353 539 7.9E-38 T 12-10-2018 VAPA_1c27100 20658859d97faf738e67d97f65032d9c 578 Pfam PF00069 Protein kinase domain 282 524 2.8E-36 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 VAPA_1c27100 20658859d97faf738e67d97f65032d9c 578 SUPERFAMILY SSF81606 7 240 3.92E-46 T 12-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 VAPA_1c27100 20658859d97faf738e67d97f65032d9c 578 Gene3D G3DSA:3.30.200.20 262 351 5.7E-10 T 12-10-2018 VAPA_1c27100 20658859d97faf738e67d97f65032d9c 578 SUPERFAMILY SSF56112 256 540 4.32E-55 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily VAPA_1c27100 20658859d97faf738e67d97f65032d9c 578 Pfam PF13672 Protein phosphatase 2C 16 196 1.5E-11 T 12-10-2018 VAPA_1c27100 20658859d97faf738e67d97f65032d9c 578 SMART SM00332 2 237 3.6E-15 T 12-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 VAPA_1c27100 20658859d97faf738e67d97f65032d9c 578 Gene3D G3DSA:3.60.40.10 1 241 3.7E-39 T 12-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 VAPA_1c27100 20658859d97faf738e67d97f65032d9c 578 ProSitePatterns PS00109 Tyrosine protein kinases specific active-site signature. 391 403 - T 12-10-2018 IPR008266 Tyrosine-protein kinase, active site GO:0004672|GO:0006468 VAPA_1c27100 20658859d97faf738e67d97f65032d9c 578 SMART SM00331 24 239 4.6E-17 T 12-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 VAPA_1c30710 9d346b15e903ae3df7674ac11c9353ca 1039 SUPERFAMILY SSF82693 136 312 1.57E-13 T 12-10-2018 VAPA_1c30710 9d346b15e903ae3df7674ac11c9353ca 1039 SUPERFAMILY SSF82714 695 781 3.01E-8 T 12-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains VAPA_1c30710 9d346b15e903ae3df7674ac11c9353ca 1039 PRINTS PR00702 Acriflavin resistance protein family signature 461 484 1.8E-50 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 VAPA_1c30710 9d346b15e903ae3df7674ac11c9353ca 1039 PRINTS PR00702 Acriflavin resistance protein family signature 38 56 1.8E-50 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 VAPA_1c30710 9d346b15e903ae3df7674ac11c9353ca 1039 PRINTS PR00702 Acriflavin resistance protein family signature 383 407 1.8E-50 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 VAPA_1c30710 9d346b15e903ae3df7674ac11c9353ca 1039 PRINTS PR00702 Acriflavin resistance protein family signature 10 34 1.8E-50 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 VAPA_1c30710 9d346b15e903ae3df7674ac11c9353ca 1039 PRINTS PR00702 Acriflavin resistance protein family signature 436 459 1.8E-50 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 VAPA_1c30710 9d346b15e903ae3df7674ac11c9353ca 1039 PRINTS PR00702 Acriflavin resistance protein family signature 355 376 1.8E-50 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 VAPA_1c30710 9d346b15e903ae3df7674ac11c9353ca 1039 PRINTS PR00702 Acriflavin resistance protein family signature 328 351 1.8E-50 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 VAPA_1c30710 9d346b15e903ae3df7674ac11c9353ca 1039 PRINTS PR00702 Acriflavin resistance protein family signature 531 548 1.8E-50 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 VAPA_1c30710 9d346b15e903ae3df7674ac11c9353ca 1039 SUPERFAMILY SSF82866 289 488 9.42E-48 T 12-10-2018 VAPA_1c30710 9d346b15e903ae3df7674ac11c9353ca 1039 SUPERFAMILY SSF82693 544 644 9.24E-7 T 12-10-2018 VAPA_1c30710 9d346b15e903ae3df7674ac11c9353ca 1039 SUPERFAMILY SSF82866 784 1009 1.7E-44 T 12-10-2018 VAPA_1c30710 9d346b15e903ae3df7674ac11c9353ca 1039 Gene3D G3DSA:3.30.70.1430 546 644 1.6E-281 T 12-10-2018 VAPA_1c30710 9d346b15e903ae3df7674ac11c9353ca 1039 Gene3D G3DSA:1.20.1640.10 500 1000 1.6E-281 T 12-10-2018 VAPA_1c30710 9d346b15e903ae3df7674ac11c9353ca 1039 Gene3D G3DSA:3.30.70.1440 645 841 1.6E-281 T 12-10-2018 VAPA_1c30710 9d346b15e903ae3df7674ac11c9353ca 1039 Gene3D G3DSA:1.20.1640.10 10 499 1.6E-281 T 12-10-2018 VAPA_1c30710 9d346b15e903ae3df7674ac11c9353ca 1039 Gene3D G3DSA:3.30.2090.10 694 784 1.6E-281 T 12-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains VAPA_1c30710 9d346b15e903ae3df7674ac11c9353ca 1039 Gene3D G3DSA:3.30.70.1430 40 792 1.6E-281 T 12-10-2018 VAPA_1c30710 9d346b15e903ae3df7674ac11c9353ca 1039 SUPERFAMILY SSF82693 40 132 3.49E-21 T 12-10-2018 VAPA_1c30710 9d346b15e903ae3df7674ac11c9353ca 1039 Gene3D G3DSA:3.30.2090.10 178 268 1.6E-281 T 12-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains VAPA_1c30710 9d346b15e903ae3df7674ac11c9353ca 1039 Pfam PF00873 AcrB/AcrD/AcrF family 5 1003 3.2E-224 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 VAPA_1c30710 9d346b15e903ae3df7674ac11c9353ca 1039 SUPERFAMILY SSF82714 182 263 9.94E-14 T 12-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains VAPA_1c30710 9d346b15e903ae3df7674ac11c9353ca 1039 Gene3D G3DSA:3.30.70.1320 134 324 1.6E-281 T 12-10-2018 VAPA_2c07940 580bb7f1712f9e0dde0bf8ed6574cab9 91 Gene3D G3DSA:1.10.10.10 4 67 4.7E-19 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_2c07940 580bb7f1712f9e0dde0bf8ed6574cab9 91 SUPERFAMILY SSF88659 7 64 8.6E-16 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like VAPA_2c07940 580bb7f1712f9e0dde0bf8ed6574cab9 91 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 2 65 5.6E-13 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 VAPA_2c07940 580bb7f1712f9e0dde0bf8ed6574cab9 91 Pfam PF08281 Sigma-70, region 4 10 60 5.7E-16 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 VAPA_1c30630 b794b6e57be295767d8a8d9d3b520fdf 254 Pfam PF00005 ABC transporter 18 177 1.2E-25 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c30630 b794b6e57be295767d8a8d9d3b520fdf 254 Gene3D G3DSA:3.40.50.300 1 252 7.3E-58 T 12-10-2018 VAPA_1c30630 b794b6e57be295767d8a8d9d3b520fdf 254 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 227 248 3.6E-6 T 12-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal VAPA_1c30630 b794b6e57be295767d8a8d9d3b520fdf 254 SMART SM00382 26 226 4.5E-9 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c30630 b794b6e57be295767d8a8d9d3b520fdf 254 SUPERFAMILY SSF52540 2 247 1.81E-56 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c27130 12d04db7e8fc20665d7757843b565105 136 Pfam PF07963 Prokaryotic N-terminal methylation motif 8 33 1.1E-10 T 12-10-2018 IPR012902 Prokaryotic N-terminal methylation site VAPA_1c27130 12d04db7e8fc20665d7757843b565105 136 Gene3D G3DSA:3.30.700.10 13 136 2.3E-27 T 12-10-2018 VAPA_1c27130 12d04db7e8fc20665d7757843b565105 136 SUPERFAMILY SSF54523 13 122 1.83E-21 T 12-10-2018 VAPA_1c27130 12d04db7e8fc20665d7757843b565105 136 PRINTS PR00813 Bacterial general secretion pathway protein G signature 12 37 6.0E-8 T 12-10-2018 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 VAPA_1c27130 12d04db7e8fc20665d7757843b565105 136 PRINTS PR00813 Bacterial general secretion pathway protein G signature 48 66 6.0E-8 T 12-10-2018 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 VAPA_1c27130 12d04db7e8fc20665d7757843b565105 136 Pfam PF16732 Type IV minor pilin ComP, DNA uptake sequence receptor 34 119 3.6E-14 T 12-10-2018 IPR031982 Type IV minor pilin ComP VAPA_1c27130 12d04db7e8fc20665d7757843b565105 136 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 10 33 7.4E-11 T 12-10-2018 IPR012902 Prokaryotic N-terminal methylation site VAPA_1c50610 4aa54eed1b1c78a4b838eb22d6637750 297 Gene3D G3DSA:3.30.470.10 5 127 6.6E-34 T 12-10-2018 VAPA_1c50610 4aa54eed1b1c78a4b838eb22d6637750 297 Gene3D G3DSA:3.20.10.10 129 292 1.2E-48 T 12-10-2018 VAPA_1c50610 4aa54eed1b1c78a4b838eb22d6637750 297 Pfam PF01063 Amino-transferase class IV 39 259 8.0E-39 T 12-10-2018 IPR001544 Aminotransferase class IV GO:0003824 Reactome: R-HSA-70895 VAPA_1c50610 4aa54eed1b1c78a4b838eb22d6637750 297 SUPERFAMILY SSF56752 11 285 3.66E-69 T 12-10-2018 IPR036038 Aminotransferase-like, PLP-dependent enzymes GO:0003824 Reactome: R-HSA-70895 VAPA_1c04810 6ff9fef8bfce897eeb2e9ef1fb19ad47 109 Gene3D G3DSA:3.30.160.100 2 96 5.4E-34 T 12-10-2018 IPR036567 Ribosome hibernation promotion factor-like VAPA_1c04810 6ff9fef8bfce897eeb2e9ef1fb19ad47 109 TIGRFAM TIGR00741 yfiA: ribosomal subunit interface protein 1 103 5.8E-31 T 12-10-2018 IPR003489 Ribosome hibernation promoting factor/RaiA GO:0044238 VAPA_1c04810 6ff9fef8bfce897eeb2e9ef1fb19ad47 109 SUPERFAMILY SSF69754 1 104 4.84E-33 T 12-10-2018 IPR036567 Ribosome hibernation promotion factor-like VAPA_1c04810 6ff9fef8bfce897eeb2e9ef1fb19ad47 109 Pfam PF02482 Sigma 54 modulation protein / S30EA ribosomal protein 4 97 1.9E-25 T 12-10-2018 IPR003489 Ribosome hibernation promoting factor/RaiA GO:0044238 VAPA_1c41860 007a8ff82d458be4838e3aef4d691fec 275 Gene3D G3DSA:3.40.190.10 122 214 4.5E-61 T 12-10-2018 VAPA_1c41860 007a8ff82d458be4838e3aef4d691fec 275 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 58 71 - T 12-10-2018 IPR018313 Solute-binding protein family 3, conserved site VAPA_1c41860 007a8ff82d458be4838e3aef4d691fec 275 SMART SM00062 34 257 1.5E-55 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF VAPA_1c41860 007a8ff82d458be4838e3aef4d691fec 275 SUPERFAMILY SSF53850 6 256 3.03E-59 T 12-10-2018 VAPA_1c41860 007a8ff82d458be4838e3aef4d691fec 275 Gene3D G3DSA:3.40.190.10 24 255 4.5E-61 T 12-10-2018 VAPA_1c41860 007a8ff82d458be4838e3aef4d691fec 275 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 35 255 2.9E-52 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF VAPA_1c48310 f0305511c7849381b1d48cb826424452 316 SUPERFAMILY SSF53335 9 312 1.09E-76 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase VAPA_1c48310 f0305511c7849381b1d48cb826424452 316 Hamap MF_00934 Ribosomal RNA large subunit methyltransferase J [rlmJ]. 2 304 37.107 T 12-10-2018 IPR007473 Ribosomal RNA large subunit methyltransferase J GO:0008649|GO:0070475 VAPA_1c48310 f0305511c7849381b1d48cb826424452 316 Gene3D G3DSA:3.40.50.150 1 316 2.0E-94 T 12-10-2018 VAPA_1c48310 f0305511c7849381b1d48cb826424452 316 Pfam PF04378 Ribosomal RNA large subunit methyltransferase D, RlmJ 34 309 3.9E-57 T 12-10-2018 IPR007473 Ribosomal RNA large subunit methyltransferase J GO:0008649|GO:0070475 VAPA_1c22210 719354805915e3aae4633efe9f4e1f4b 1025 Gene3D G3DSA:3.30.2090.10 709 797 4.1E-229 T 12-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains VAPA_1c22210 719354805915e3aae4633efe9f4e1f4b 1025 SUPERFAMILY SSF82714 190 271 1.96E-13 T 12-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains VAPA_1c22210 719354805915e3aae4633efe9f4e1f4b 1025 PRINTS PR00702 Acriflavin resistance protein family signature 361 382 6.2E-19 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 VAPA_1c22210 719354805915e3aae4633efe9f4e1f4b 1025 PRINTS PR00702 Acriflavin resistance protein family signature 43 61 6.2E-19 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 VAPA_1c22210 719354805915e3aae4633efe9f4e1f4b 1025 PRINTS PR00702 Acriflavin resistance protein family signature 442 465 6.2E-19 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 VAPA_1c22210 719354805915e3aae4633efe9f4e1f4b 1025 PRINTS PR00702 Acriflavin resistance protein family signature 467 490 6.2E-19 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 VAPA_1c22210 719354805915e3aae4633efe9f4e1f4b 1025 PRINTS PR00702 Acriflavin resistance protein family signature 389 413 6.2E-19 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 VAPA_1c22210 719354805915e3aae4633efe9f4e1f4b 1025 SUPERFAMILY SSF82714 710 795 6.02E-14 T 12-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains VAPA_1c22210 719354805915e3aae4633efe9f4e1f4b 1025 SUPERFAMILY SSF82693 45 140 9.24E-16 T 12-10-2018 VAPA_1c22210 719354805915e3aae4633efe9f4e1f4b 1025 Gene3D G3DSA:3.30.70.1440 658 857 4.1E-229 T 12-10-2018 VAPA_1c22210 719354805915e3aae4633efe9f4e1f4b 1025 SUPERFAMILY SSF82866 299 493 2.35E-34 T 12-10-2018 VAPA_1c22210 719354805915e3aae4633efe9f4e1f4b 1025 Gene3D G3DSA:3.30.70.1320 142 331 4.1E-229 T 12-10-2018 VAPA_1c22210 719354805915e3aae4633efe9f4e1f4b 1025 Gene3D G3DSA:1.20.1640.10 18 506 4.1E-229 T 12-10-2018 VAPA_1c22210 719354805915e3aae4633efe9f4e1f4b 1025 SUPERFAMILY SSF82693 557 644 1.26E-5 T 12-10-2018 VAPA_1c22210 719354805915e3aae4633efe9f4e1f4b 1025 SUPERFAMILY SSF82866 794 1017 1.06E-42 T 12-10-2018 VAPA_1c22210 719354805915e3aae4633efe9f4e1f4b 1025 Gene3D G3DSA:1.20.1640.10 507 1009 4.1E-229 T 12-10-2018 VAPA_1c22210 719354805915e3aae4633efe9f4e1f4b 1025 SUPERFAMILY SSF82693 145 329 3.92E-13 T 12-10-2018 VAPA_1c22210 719354805915e3aae4633efe9f4e1f4b 1025 Gene3D G3DSA:3.30.70.1430 45 805 4.1E-229 T 12-10-2018 VAPA_1c22210 719354805915e3aae4633efe9f4e1f4b 1025 Gene3D G3DSA:3.30.2090.10 184 273 4.1E-229 T 12-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains VAPA_1c22210 719354805915e3aae4633efe9f4e1f4b 1025 Gene3D G3DSA:3.30.70.1430 558 657 4.1E-229 T 12-10-2018 VAPA_1c22210 719354805915e3aae4633efe9f4e1f4b 1025 Pfam PF00873 AcrB/AcrD/AcrF family 9 1010 1.5E-147 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 VAPA_1c54370 65875848f6ddc0d2950baf34deec1842 242 SMART SM00895 96 220 1.8E-21 T 12-10-2018 IPR011711 GntR, C-terminal VAPA_1c54370 65875848f6ddc0d2950baf34deec1842 242 Gene3D G3DSA:1.20.120.530 90 234 8.3E-27 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal VAPA_1c54370 65875848f6ddc0d2950baf34deec1842 242 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 46 57 6.2E-6 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 VAPA_1c54370 65875848f6ddc0d2950baf34deec1842 242 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 57 76 6.2E-6 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 VAPA_1c54370 65875848f6ddc0d2950baf34deec1842 242 Pfam PF00392 Bacterial regulatory proteins, gntR family 28 86 7.0E-16 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_1c54370 65875848f6ddc0d2950baf34deec1842 242 Pfam PF07729 FCD domain 96 219 4.3E-24 T 12-10-2018 IPR011711 GntR, C-terminal VAPA_1c54370 65875848f6ddc0d2950baf34deec1842 242 SUPERFAMILY SSF48008 92 228 2.2E-27 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal VAPA_1c54370 65875848f6ddc0d2950baf34deec1842 242 SUPERFAMILY SSF46785 19 90 3.4E-17 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c54370 65875848f6ddc0d2950baf34deec1842 242 Gene3D G3DSA:1.10.10.10 22 87 1.2E-19 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c54370 65875848f6ddc0d2950baf34deec1842 242 SMART SM00345 28 86 3.7E-13 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_1c37560 e0286c62df0390f257555f324c75dd51 103 Gene3D G3DSA:3.30.70.100 2 99 3.4E-20 T 12-10-2018 VAPA_1c37560 e0286c62df0390f257555f324c75dd51 103 Pfam PF03992 Antibiotic biosynthesis monooxygenase 1 74 2.5E-11 T 12-10-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain VAPA_1c37560 e0286c62df0390f257555f324c75dd51 103 SUPERFAMILY SSF54909 1 92 5.37E-21 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel VAPA_1c10920 9fd8d7ed3b7a8cf2b15e57d838d035e5 356 Gene3D G3DSA:2.70.98.10 2 354 5.3E-120 T 12-10-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 VAPA_1c10920 9fd8d7ed3b7a8cf2b15e57d838d035e5 356 PIRSF PIRSF005096 1 355 1.1E-122 T 12-10-2018 IPR015443 Aldose 1-epimerase GO:0016853|GO:0019318 KEGG: 00010+5.1.3.3|KEGG: 00052+5.1.3.3|MetaCyc: PWY-6317 VAPA_1c10920 9fd8d7ed3b7a8cf2b15e57d838d035e5 356 SUPERFAMILY SSF74650 7 352 7.53E-108 T 12-10-2018 IPR011013 Galactose mutarotase-like domain superfamily GO:0003824|GO:0005975|GO:0030246 VAPA_1c10920 9fd8d7ed3b7a8cf2b15e57d838d035e5 356 Pfam PF01263 Aldose 1-epimerase 22 349 7.6E-82 T 12-10-2018 IPR008183 Aldose 1-/Glucose-6-phosphate 1-epimerase GO:0005975|GO:0016853 VAPA_1c39290 c9295fbf9f5abda063a1b5d2743c30f3 973 Pfam PF00801 PKD domain 748 788 3.0E-5 T 12-10-2018 IPR000601 PKD domain VAPA_1c39290 c9295fbf9f5abda063a1b5d2743c30f3 973 SMART SM00089 710 799 6.7E-6 T 12-10-2018 IPR022409 PKD/Chitinase domain VAPA_1c39290 c9295fbf9f5abda063a1b5d2743c30f3 973 Gene3D G3DSA:3.60.10.10 384 700 6.4E-36 T 12-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily VAPA_1c39290 c9295fbf9f5abda063a1b5d2743c30f3 973 SUPERFAMILY SSF56219 384 700 2.16E-34 T 12-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily VAPA_1c39290 c9295fbf9f5abda063a1b5d2743c30f3 973 SUPERFAMILY SSF49299 706 797 9.29E-10 T 12-10-2018 IPR035986 PKD domain superfamily VAPA_1c39290 c9295fbf9f5abda063a1b5d2743c30f3 973 Gene3D G3DSA:2.60.40.10 707 800 3.1E-12 T 12-10-2018 IPR013783 Immunoglobulin-like fold VAPA_1c39290 c9295fbf9f5abda063a1b5d2743c30f3 973 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 423 693 5.2E-9 T 12-10-2018 IPR005135 Endonuclease/exonuclease/phosphatase VAPA_1c39290 c9295fbf9f5abda063a1b5d2743c30f3 973 Pfam PF00932 Lamin Tail Domain 804 912 2.3E-14 T 12-10-2018 IPR001322 Lamin tail domain VAPA_2c06100 8202f116bd8fecc7a067be969fe92985 307 SUPERFAMILY SSF103481 47 148 2.35E-6 T 12-10-2018 VAPA_2c06100 8202f116bd8fecc7a067be969fe92985 307 Pfam PF00892 EamA-like transporter family 161 294 9.8E-12 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 VAPA_2c06100 8202f116bd8fecc7a067be969fe92985 307 Pfam PF00892 EamA-like transporter family 15 145 4.1E-16 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 VAPA_2c06100 8202f116bd8fecc7a067be969fe92985 307 SUPERFAMILY SSF103481 195 299 2.35E-12 T 12-10-2018 VAPA_1c43530 f4a27f34a59777653f1283c22d6eb38e 404 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 1 386 1.2E-92 T 12-10-2018 IPR020013 Flagellar hook-basal body protein, FlgE/F/G VAPA_1c43530 f4a27f34a59777653f1283c22d6eb38e 404 Pfam PF07559 Flagellar basal body protein FlaE 171 284 1.1E-21 T 12-10-2018 IPR011491 Flagellar hook protein FlgE VAPA_1c43530 f4a27f34a59777653f1283c22d6eb38e 404 Pfam PF00460 Flagella basal body rod protein 4 33 2.5E-10 T 12-10-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 VAPA_1c43530 f4a27f34a59777653f1283c22d6eb38e 404 SUPERFAMILY SSF117143 72 365 1.96E-76 T 12-10-2018 IPR037925 Flagellar hook-basal body protein, FlgE/F/G-like VAPA_1c43530 f4a27f34a59777653f1283c22d6eb38e 404 Gene3D G3DSA:2.60.98.20 145 285 3.6E-36 T 12-10-2018 IPR037058 Flagellar hook protein FlgE superfamily VAPA_1c43530 f4a27f34a59777653f1283c22d6eb38e 404 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 324 403 1.2E-19 T 12-10-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain VAPA_1c01990 968ff3cddb4a17b61a0f1b38d05e699e 189 Gene3D G3DSA:2.60.120.10 10 172 4.1E-46 T 12-10-2018 IPR014710 RmlC-like jelly roll fold VAPA_1c01990 968ff3cddb4a17b61a0f1b38d05e699e 189 Gene3D G3DSA:2.60.120.10 12 117 4.1E-46 T 12-10-2018 IPR014710 RmlC-like jelly roll fold VAPA_1c01990 968ff3cddb4a17b61a0f1b38d05e699e 189 Pfam PF05962 HutD 10 176 4.6E-54 T 12-10-2018 IPR010282 Uncharacterised protein family HutD/Ves VAPA_1c01990 968ff3cddb4a17b61a0f1b38d05e699e 189 SUPERFAMILY SSF51182 2 177 1.25E-51 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily VAPA_1c53730 058596048bdac2b7b050eb809b936c15 407 Pfam PF02371 Transposase IS116/IS110/IS902 family 251 333 1.3E-20 T 12-10-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 VAPA_1c53730 058596048bdac2b7b050eb809b936c15 407 Pfam PF01548 Transposase 9 154 5.1E-26 T 12-10-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 VAPA_1c13310 058596048bdac2b7b050eb809b936c15 407 Pfam PF02371 Transposase IS116/IS110/IS902 family 251 333 1.3E-20 T 12-10-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 VAPA_1c13310 058596048bdac2b7b050eb809b936c15 407 Pfam PF01548 Transposase 9 154 5.1E-26 T 12-10-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 VAPA_1c02490 058596048bdac2b7b050eb809b936c15 407 Pfam PF02371 Transposase IS116/IS110/IS902 family 251 333 1.3E-20 T 12-10-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 VAPA_1c02490 058596048bdac2b7b050eb809b936c15 407 Pfam PF01548 Transposase 9 154 5.1E-26 T 12-10-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 VAPA_2c05800 058596048bdac2b7b050eb809b936c15 407 Pfam PF02371 Transposase IS116/IS110/IS902 family 251 333 1.3E-20 T 12-10-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 VAPA_2c05800 058596048bdac2b7b050eb809b936c15 407 Pfam PF01548 Transposase 9 154 5.1E-26 T 12-10-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 VAPA_2c05880 1d719cd0bdd4999b60a65f94234a9651 103 SUPERFAMILY SSF143120 7 82 1.44E-10 T 12-10-2018 IPR036165 YefM-like superfamily VAPA_2c05880 1d719cd0bdd4999b60a65f94234a9651 103 Gene3D G3DSA:3.40.1620.10 4 44 1.3E-9 T 12-10-2018 VAPA_2c05880 1d719cd0bdd4999b60a65f94234a9651 103 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 7 74 1.4E-14 T 12-10-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM VAPA_2c05880 1d719cd0bdd4999b60a65f94234a9651 103 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 9 50 8.5E-9 T 12-10-2018 VAPA_1c29080 923e9aaacb00597d0f487e1fcecc8fce 464 Pfam PF13742 OB-fold nucleic acid binding domain 44 136 8.7E-28 T 12-10-2018 IPR025824 OB-fold nucleic acid binding domain GO:0003676 VAPA_1c29080 923e9aaacb00597d0f487e1fcecc8fce 464 TIGRFAM TIGR00237 xseA: exodeoxyribonuclease VII, large subunit 45 451 1.6E-126 T 12-10-2018 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 VAPA_1c29080 923e9aaacb00597d0f487e1fcecc8fce 464 Hamap MF_00378 Exodeoxyribonuclease 7 large subunit [xseA]. 40 452 25.95 T 12-10-2018 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 VAPA_1c29080 923e9aaacb00597d0f487e1fcecc8fce 464 Pfam PF02601 Exonuclease VII, large subunit 159 449 6.4E-86 T 12-10-2018 IPR020579 Exonuclease VII, large subunit, C-terminal GO:0008855 VAPA_1c26390 a1325ef9c9c337032f7194794ca71b68 312 Gene3D G3DSA:3.40.30.110 211 310 5.4E-23 T 12-10-2018 VAPA_1c26390 a1325ef9c9c337032f7194794ca71b68 312 Pfam PF13417 Glutathione S-transferase, N-terminal domain 6 79 5.4E-13 T 12-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 VAPA_1c26390 a1325ef9c9c337032f7194794ca71b68 312 SUPERFAMILY SSF47616 86 217 6.96E-12 T 12-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily VAPA_1c26390 a1325ef9c9c337032f7194794ca71b68 312 Gene3D G3DSA:1.20.1050.10 93 210 2.7E-32 T 12-10-2018 VAPA_1c26390 a1325ef9c9c337032f7194794ca71b68 312 Gene3D G3DSA:3.40.30.10 1 92 1.6E-8 T 12-10-2018 VAPA_1c26390 a1325ef9c9c337032f7194794ca71b68 312 Pfam PF13410 Glutathione S-transferase, C-terminal domain 155 213 8.3E-7 T 12-10-2018 VAPA_1c26390 a1325ef9c9c337032f7194794ca71b68 312 SUPERFAMILY SSF52833 3 103 5.38E-16 T 12-10-2018 IPR036249 Thioredoxin-like superfamily VAPA_1c29370 ef63cd6a216bb063ba9e330405ea4d0b 387 Hamap MF_01209 Carbamoyl-phosphate synthase small chain [carA]. 8 386 47.965 T 12-10-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 VAPA_1c29370 ef63cd6a216bb063ba9e330405ea4d0b 387 PRINTS PR00096 Glutamine amidotransferase superfamily signature 357 370 2.4E-9 T 12-10-2018 VAPA_1c29370 ef63cd6a216bb063ba9e330405ea4d0b 387 PRINTS PR00096 Glutamine amidotransferase superfamily signature 244 253 2.4E-9 T 12-10-2018 VAPA_1c29370 ef63cd6a216bb063ba9e330405ea4d0b 387 PRINTS PR00096 Glutamine amidotransferase superfamily signature 272 283 2.4E-9 T 12-10-2018 VAPA_1c29370 ef63cd6a216bb063ba9e330405ea4d0b 387 SMART SM01097 8 138 5.0E-87 T 12-10-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 VAPA_1c29370 ef63cd6a216bb063ba9e330405ea4d0b 387 Gene3D G3DSA:3.50.30.20 8 155 5.3E-56 T 12-10-2018 IPR036480 Carbamoyl-phosphate synthase small subunit, N-terminal domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 VAPA_1c29370 ef63cd6a216bb063ba9e330405ea4d0b 387 SUPERFAMILY SSF52021 9 148 1.96E-55 T 12-10-2018 IPR036480 Carbamoyl-phosphate synthase small subunit, N-terminal domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 VAPA_1c29370 ef63cd6a216bb063ba9e330405ea4d0b 387 Pfam PF00988 Carbamoyl-phosphate synthase small chain, CPSase domain 10 137 2.4E-51 T 12-10-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 VAPA_1c29370 ef63cd6a216bb063ba9e330405ea4d0b 387 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 314 325 6.9E-40 T 12-10-2018 VAPA_1c29370 ef63cd6a216bb063ba9e330405ea4d0b 387 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 241 255 6.9E-40 T 12-10-2018 VAPA_1c29370 ef63cd6a216bb063ba9e330405ea4d0b 387 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 272 288 6.9E-40 T 12-10-2018 VAPA_1c29370 ef63cd6a216bb063ba9e330405ea4d0b 387 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 289 306 6.9E-40 T 12-10-2018 VAPA_1c29370 ef63cd6a216bb063ba9e330405ea4d0b 387 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 202 216 6.9E-40 T 12-10-2018 VAPA_1c29370 ef63cd6a216bb063ba9e330405ea4d0b 387 Gene3D G3DSA:3.40.50.880 163 386 3.1E-71 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like VAPA_1c29370 ef63cd6a216bb063ba9e330405ea4d0b 387 SUPERFAMILY SSF52317 165 384 1.32E-59 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like VAPA_1c29370 ef63cd6a216bb063ba9e330405ea4d0b 387 TIGRFAM TIGR01368 CPSaseIIsmall: carbamoyl-phosphate synthase, small subunit 10 383 2.5E-142 T 12-10-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 VAPA_1c29370 ef63cd6a216bb063ba9e330405ea4d0b 387 Pfam PF00117 Glutamine amidotransferase class-I 205 379 4.4E-45 T 12-10-2018 IPR017926 Glutamine amidotransferase VAPA_2c05630 4305712f994573158f8d83386b23d2f6 386 Gene3D G3DSA:1.20.140.10 231 386 3.1E-25 T 12-10-2018 VAPA_2c05630 4305712f994573158f8d83386b23d2f6 386 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 8 116 6.2E-17 T 12-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 VAPA_2c05630 4305712f994573158f8d83386b23d2f6 386 SUPERFAMILY SSF56645 6 239 8.12E-69 T 12-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 VAPA_2c05630 4305712f994573158f8d83386b23d2f6 386 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 227 383 3.5E-17 T 12-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 VAPA_2c05630 4305712f994573158f8d83386b23d2f6 386 SUPERFAMILY SSF47203 227 385 6.44E-15 T 12-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 VAPA_2c05630 4305712f994573158f8d83386b23d2f6 386 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 121 215 8.2E-23 T 12-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 VAPA_2c05630 4305712f994573158f8d83386b23d2f6 386 Gene3D G3DSA:1.10.540.10 3 116 6.2E-25 T 12-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 VAPA_2c05630 4305712f994573158f8d83386b23d2f6 386 Gene3D G3DSA:2.40.110.10 121 230 1.8E-37 T 12-10-2018 VAPA_1c39430 bc5ffad6af88902ffc8ccc2d16f29a0b 479 Gene3D G3DSA:3.40.605.10 14 454 2.0E-143 T 12-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 VAPA_1c39430 bc5ffad6af88902ffc8ccc2d16f29a0b 479 Gene3D G3DSA:3.40.309.10 221 415 2.0E-143 T 12-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 VAPA_1c39430 bc5ffad6af88902ffc8ccc2d16f29a0b 479 Pfam PF00171 Aldehyde dehydrogenase family 8 272 2.4E-18 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 VAPA_1c39430 bc5ffad6af88902ffc8ccc2d16f29a0b 479 SUPERFAMILY SSF53720 11 457 2.75E-62 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 VAPA_2c07060 e98d47064a71926bdc2a710be70a9f3d 284 SUPERFAMILY SSF55781 79 268 4.9E-36 T 12-10-2018 VAPA_2c07060 e98d47064a71926bdc2a710be70a9f3d 284 Pfam PF01614 Bacterial transcriptional regulator 140 265 3.4E-15 T 12-10-2018 IPR014757 Transcription regulator IclR, C-terminal VAPA_2c07060 e98d47064a71926bdc2a710be70a9f3d 284 Pfam PF09339 IclR helix-turn-helix domain 29 73 3.9E-7 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 VAPA_2c07060 e98d47064a71926bdc2a710be70a9f3d 284 SUPERFAMILY SSF46785 21 94 3.1E-10 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_2c07060 e98d47064a71926bdc2a710be70a9f3d 284 Gene3D G3DSA:3.30.450.40 98 280 2.4E-32 T 12-10-2018 IPR029016 GAF-like domain superfamily VAPA_2c07060 e98d47064a71926bdc2a710be70a9f3d 284 Gene3D G3DSA:1.10.10.10 14 89 2.2E-10 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_2c07060 e98d47064a71926bdc2a710be70a9f3d 284 SMART SM00346 21 110 1.2E-8 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 VAPA_1c21500 0b70ac33dd6209d1e48a1fdbcea5c08c 334 Gene3D G3DSA:3.40.190.150 34 327 4.5E-102 T 12-10-2018 VAPA_1c21500 0b70ac33dd6209d1e48a1fdbcea5c08c 334 PIRSF PIRSF017082 3 334 2.9E-73 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c21500 0b70ac33dd6209d1e48a1fdbcea5c08c 334 Gene3D G3DSA:3.40.190.10 132 256 4.5E-102 T 12-10-2018 VAPA_1c21500 0b70ac33dd6209d1e48a1fdbcea5c08c 334 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 54 330 3.9E-79 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c21500 0b70ac33dd6209d1e48a1fdbcea5c08c 334 SUPERFAMILY SSF53850 117 290 2.9E-11 T 12-10-2018 VAPA_1c53430 9fd4e82372c7118d77633500c2dfb058 393 PIRSF PIRSF019422 11 393 1.6E-82 T 12-10-2018 IPR026044 Membrane-bound lytic murein transglycosylase A VAPA_1c53430 9fd4e82372c7118d77633500c2dfb058 393 Gene3D G3DSA:2.40.240.50 177 294 3.1E-34 T 12-10-2018 VAPA_1c53430 9fd4e82372c7118d77633500c2dfb058 393 Pfam PF03562 MltA specific insert domain 83 293 1.7E-49 T 12-10-2018 IPR005300 Lytic transglycosylase MltA, domain B GO:0004553 VAPA_1c53430 9fd4e82372c7118d77633500c2dfb058 393 Gene3D G3DSA:2.40.40.10 302 393 3.9E-33 T 12-10-2018 IPR036908 RlpA-like domain superfamily VAPA_1c53430 9fd4e82372c7118d77633500c2dfb058 393 Gene3D G3DSA:2.40.40.10 51 168 7.0E-16 T 12-10-2018 IPR036908 RlpA-like domain superfamily VAPA_1c53430 9fd4e82372c7118d77633500c2dfb058 393 SMART SM00925 153 293 6.3E-55 T 12-10-2018 IPR005300 Lytic transglycosylase MltA, domain B GO:0004553 VAPA_1c53430 9fd4e82372c7118d77633500c2dfb058 393 Pfam PF06725 3D domain 318 389 2.4E-19 T 12-10-2018 IPR010611 3D domain GO:0004553|GO:0009254|GO:0019867 VAPA_1c53430 9fd4e82372c7118d77633500c2dfb058 393 SUPERFAMILY SSF50685 62 393 8.37E-99 T 12-10-2018 IPR036908 RlpA-like domain superfamily VAPA_1c22860 55a9d06a28bc7234957f34605de63ae6 351 TIGRFAM TIGR03217 4OH_2_O_val_ald: 4-hydroxy-2-oxovalerate aldolase 2 335 1.6E-177 T 12-10-2018 IPR017629 4-hydroxy-2-oxovalerate aldolase GO:0008701|GO:0019439 KEGG: 00360+4.1.3.39|KEGG: 00362+4.1.3.39|KEGG: 00621+4.1.3.39|KEGG: 00622+4.1.3.39|MetaCyc: PWY-5162 VAPA_1c22860 55a9d06a28bc7234957f34605de63ae6 351 SUPERFAMILY SSF89000 286 335 4.71E-19 T 12-10-2018 VAPA_1c22860 55a9d06a28bc7234957f34605de63ae6 351 Hamap MF_01656 4-hydroxy-2-oxovalerate aldolase [mhpE]. 1 340 222.854 T 12-10-2018 IPR017629 4-hydroxy-2-oxovalerate aldolase GO:0008701|GO:0019439 KEGG: 00360+4.1.3.39|KEGG: 00362+4.1.3.39|KEGG: 00621+4.1.3.39|KEGG: 00622+4.1.3.39|MetaCyc: PWY-5162 VAPA_1c22860 55a9d06a28bc7234957f34605de63ae6 351 SUPERFAMILY SSF51569 1 274 2.56E-68 T 12-10-2018 VAPA_1c22860 55a9d06a28bc7234957f34605de63ae6 351 Gene3D G3DSA:3.20.20.70 1 266 2.3E-89 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 VAPA_1c22860 55a9d06a28bc7234957f34605de63ae6 351 ProDom PD005364 ALDOLASE 4-HYDROXY-2-OXOVALERATE LYASE PYRUVATE 4.1.3.- PLASMID HMG-COA LYASE-LIKE TRANSFERASE HOA 270 334 5.0E-27 T 12-10-2018 IPR012425 DmpG-like communication GO:0016833|GO:0019439 KEGG: 00360+4.1.3.39|KEGG: 00362+4.1.3.39|KEGG: 00621+4.1.3.39|KEGG: 00622+4.1.3.39|MetaCyc: PWY-5162 VAPA_1c22860 55a9d06a28bc7234957f34605de63ae6 351 Pfam PF00682 HMGL-like 3 262 1.3E-74 T 12-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 VAPA_1c22860 55a9d06a28bc7234957f34605de63ae6 351 Pfam PF07836 DmpG-like communication domain 272 332 1.7E-30 T 12-10-2018 IPR012425 DmpG-like communication GO:0016833|GO:0019439 KEGG: 00360+4.1.3.39|KEGG: 00362+4.1.3.39|KEGG: 00621+4.1.3.39|KEGG: 00622+4.1.3.39|MetaCyc: PWY-5162 VAPA_1c22860 55a9d06a28bc7234957f34605de63ae6 351 Gene3D G3DSA:1.10.8.60 273 339 1.9E-33 T 12-10-2018 VAPA_1c01600 b8b8acdba4675d973c870df7df3a0adf 312 TIGRFAM TIGR03814 Gln_ase: glutaminase A 10 312 3.5E-117 T 12-10-2018 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 VAPA_1c01600 b8b8acdba4675d973c870df7df3a0adf 312 Pfam PF04960 Glutaminase 25 312 8.0E-106 T 12-10-2018 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 VAPA_1c01600 b8b8acdba4675d973c870df7df3a0adf 312 SUPERFAMILY SSF56601 4 312 2.08E-105 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like VAPA_1c01600 b8b8acdba4675d973c870df7df3a0adf 312 Gene3D G3DSA:3.40.710.10 2 312 4.4E-104 T 12-10-2018 VAPA_1c01600 b8b8acdba4675d973c870df7df3a0adf 312 Hamap MF_00313 Glutaminase [glsA]. 6 312 43.694 T 12-10-2018 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 VAPA_1c47550 97665428e11e039f62a22bb20f21f161 320 Gene3D G3DSA:3.40.50.1370 148 303 5.4E-90 T 12-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 VAPA_1c47550 97665428e11e039f62a22bb20f21f161 320 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 17 160 2.2E-38 T 12-10-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 VAPA_1c47550 97665428e11e039f62a22bb20f21f161 320 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 62 69 - T 12-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 VAPA_1c47550 97665428e11e039f62a22bb20f21f161 320 Gene3D G3DSA:3.40.50.1370 17 312 5.4E-90 T 12-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 VAPA_1c47550 97665428e11e039f62a22bb20f21f161 320 TIGRFAM TIGR00670 asp_carb_tr: aspartate carbamoyltransferase 17 315 2.4E-91 T 12-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 VAPA_1c47550 97665428e11e039f62a22bb20f21f161 320 Hamap MF_00001 Aspartate carbamoyltransferase [pyrB]. 15 318 40.524 T 12-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 VAPA_1c47550 97665428e11e039f62a22bb20f21f161 320 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 281 304 4.8E-18 T 12-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 VAPA_1c47550 97665428e11e039f62a22bb20f21f161 320 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 148 159 4.8E-18 T 12-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 VAPA_1c47550 97665428e11e039f62a22bb20f21f161 320 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 62 81 4.8E-18 T 12-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 VAPA_1c47550 97665428e11e039f62a22bb20f21f161 320 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 269 278 4.8E-18 T 12-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 VAPA_1c47550 97665428e11e039f62a22bb20f21f161 320 PRINTS PR00101 Aspartate carbamoyltransferase signature 90 99 1.1E-27 T 12-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 VAPA_1c47550 97665428e11e039f62a22bb20f21f161 320 PRINTS PR00101 Aspartate carbamoyltransferase signature 147 164 1.1E-27 T 12-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 VAPA_1c47550 97665428e11e039f62a22bb20f21f161 320 PRINTS PR00101 Aspartate carbamoyltransferase signature 232 241 1.1E-27 T 12-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 VAPA_1c47550 97665428e11e039f62a22bb20f21f161 320 PRINTS PR00101 Aspartate carbamoyltransferase signature 52 74 1.1E-27 T 12-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 VAPA_1c47550 97665428e11e039f62a22bb20f21f161 320 PRINTS PR00101 Aspartate carbamoyltransferase signature 297 311 1.1E-27 T 12-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 VAPA_1c47550 97665428e11e039f62a22bb20f21f161 320 PRINTS PR00101 Aspartate carbamoyltransferase signature 273 278 1.1E-27 T 12-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 VAPA_1c47550 97665428e11e039f62a22bb20f21f161 320 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 168 313 1.8E-25 T 12-10-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 VAPA_1c47550 97665428e11e039f62a22bb20f21f161 320 SUPERFAMILY SSF53671 17 318 4.45E-93 T 12-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 VAPA_1c12090 1d875cf6f4f67f790582e1a673740b18 293 Pfam PF13679 Methyltransferase domain 52 192 6.8E-42 T 12-10-2018 IPR025714 Methyltransferase domain VAPA_1c12090 1d875cf6f4f67f790582e1a673740b18 293 Gene3D G3DSA:3.40.50.150 37 193 4.5E-6 T 12-10-2018 VAPA_1c12090 1d875cf6f4f67f790582e1a673740b18 293 SUPERFAMILY SSF53335 56 189 7.51E-14 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase VAPA_1c53010 f30f009c776894896d83d0f87e5c35d3 246 Pfam PF03591 AzlC protein 24 168 2.6E-32 T 12-10-2018 IPR011606 Branched-chain amino acid transport, permease VAPA_1c28490 c95022ef7bcce60d5f4dccb07b031fea 238 Pfam PF00717 Peptidase S24-like 149 220 1.4E-10 T 12-10-2018 IPR015927 Peptidase S24/S26A/S26B/S26C VAPA_1c28490 c95022ef7bcce60d5f4dccb07b031fea 238 Gene3D G3DSA:1.10.260.40 1 68 2.1E-18 T 12-10-2018 VAPA_1c28490 c95022ef7bcce60d5f4dccb07b031fea 238 Gene3D G3DSA:2.10.109.10 106 233 1.9E-30 T 12-10-2018 VAPA_1c28490 c95022ef7bcce60d5f4dccb07b031fea 238 SUPERFAMILY SSF51306 142 234 6.8E-20 T 12-10-2018 IPR036286 LexA/Signal peptidase-like superfamily VAPA_1c28490 c95022ef7bcce60d5f4dccb07b031fea 238 SUPERFAMILY SSF47413 2 67 1.29E-9 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 VAPA_1c28490 c95022ef7bcce60d5f4dccb07b031fea 238 Pfam PF13560 Helix-turn-helix domain 10 59 3.3E-9 T 12-10-2018 VAPA_1c28490 c95022ef7bcce60d5f4dccb07b031fea 238 SMART SM00530 7 61 2.9E-7 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 VAPA_2c02410 8b648727e496162306366d49c2c81ffa 268 SUPERFAMILY SSF48256 7 241 8.64E-43 T 12-10-2018 IPR036969 Citrate synthase superfamily GO:0046912 VAPA_2c02410 8b648727e496162306366d49c2c81ffa 268 Pfam PF00285 Citrate synthase, C-terminal domain 34 238 1.4E-25 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 VAPA_2c02410 8b648727e496162306366d49c2c81ffa 268 Gene3D G3DSA:1.10.580.10 35 236 2.1E-27 T 12-10-2018 IPR016142 Citrate synthase-like, large alpha subdomain Reactome: R-HSA-1268020|Reactome: R-HSA-71403 VAPA_2c02410 8b648727e496162306366d49c2c81ffa 268 Gene3D G3DSA:1.10.230.10 106 211 2.1E-27 T 12-10-2018 IPR016143 Citrate synthase-like, small alpha subdomain VAPA_1c20380 00e36398bbcb0bed1f4b69dad0b6bad8 405 Gene3D G3DSA:3.30.390.30 318 405 4.5E-28 T 12-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 VAPA_1c20380 00e36398bbcb0bed1f4b69dad0b6bad8 405 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 233 249 1.1E-23 T 12-10-2018 VAPA_1c20380 00e36398bbcb0bed1f4b69dad0b6bad8 405 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 258 280 1.1E-23 T 12-10-2018 VAPA_1c20380 00e36398bbcb0bed1f4b69dad0b6bad8 405 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 1.1E-23 T 12-10-2018 VAPA_1c20380 00e36398bbcb0bed1f4b69dad0b6bad8 405 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 147 165 1.1E-23 T 12-10-2018 VAPA_1c20380 00e36398bbcb0bed1f4b69dad0b6bad8 405 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 102 120 1.1E-23 T 12-10-2018 VAPA_1c20380 00e36398bbcb0bed1f4b69dad0b6bad8 405 Gene3D G3DSA:3.50.50.60 6 309 2.0E-105 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c20380 00e36398bbcb0bed1f4b69dad0b6bad8 405 SUPERFAMILY SSF55424 316 405 3.3E-29 T 12-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 VAPA_1c20380 00e36398bbcb0bed1f4b69dad0b6bad8 405 Pfam PF14759 Reductase C-terminal 322 405 8.9E-29 T 12-10-2018 IPR028202 Reductase, C-terminal VAPA_1c20380 00e36398bbcb0bed1f4b69dad0b6bad8 405 Gene3D G3DSA:3.50.50.60 115 240 2.0E-105 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c20380 00e36398bbcb0bed1f4b69dad0b6bad8 405 SUPERFAMILY SSF51905 146 312 3.56E-31 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c20380 00e36398bbcb0bed1f4b69dad0b6bad8 405 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 273 280 1.8E-14 T 12-10-2018 VAPA_1c20380 00e36398bbcb0bed1f4b69dad0b6bad8 405 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 5 27 1.8E-14 T 12-10-2018 VAPA_1c20380 00e36398bbcb0bed1f4b69dad0b6bad8 405 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 147 172 1.8E-14 T 12-10-2018 VAPA_1c20380 00e36398bbcb0bed1f4b69dad0b6bad8 405 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 234 248 1.8E-14 T 12-10-2018 VAPA_1c20380 00e36398bbcb0bed1f4b69dad0b6bad8 405 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 303 2.5E-66 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 VAPA_1c20380 00e36398bbcb0bed1f4b69dad0b6bad8 405 SUPERFAMILY SSF51905 3 193 7.2E-48 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_2c01230 334fba0e09c2f155d41c9837eb92cdf5 722 Pfam PF13432 Tetratricopeptide repeat 105 167 1.5E-9 T 12-10-2018 VAPA_2c01230 334fba0e09c2f155d41c9837eb92cdf5 722 Pfam PF13844 Glycosyl transferase family 41 511 705 1.8E-49 T 12-10-2018 IPR029489 O-GlcNAc transferase, C-terminal KEGG: 00514+2.4.1.255|MetaCyc: PWY-7437|Reactome: R-HSA-3214847|Reactome: R-HSA-5689603 VAPA_2c01230 334fba0e09c2f155d41c9837eb92cdf5 722 Pfam PF13844 Glycosyl transferase family 41 351 503 9.2E-36 T 12-10-2018 IPR029489 O-GlcNAc transferase, C-terminal KEGG: 00514+2.4.1.255|MetaCyc: PWY-7437|Reactome: R-HSA-3214847|Reactome: R-HSA-5689603 VAPA_2c01230 334fba0e09c2f155d41c9837eb92cdf5 722 Pfam PF13371 Tetratricopeptide repeat 175 244 4.9E-10 T 12-10-2018 VAPA_2c01230 334fba0e09c2f155d41c9837eb92cdf5 722 Gene3D G3DSA:1.25.40.10 26 306 2.3E-47 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 VAPA_2c01230 334fba0e09c2f155d41c9837eb92cdf5 722 SMART SM00028 201 234 2.0E-4 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 VAPA_2c01230 334fba0e09c2f155d41c9837eb92cdf5 722 SMART SM00028 99 132 0.18 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 VAPA_2c01230 334fba0e09c2f155d41c9837eb92cdf5 722 SMART SM00028 167 200 4.7E-4 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 VAPA_2c01230 334fba0e09c2f155d41c9837eb92cdf5 722 SMART SM00028 65 98 450.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 VAPA_2c01230 334fba0e09c2f155d41c9837eb92cdf5 722 SMART SM00028 133 166 0.0021 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 VAPA_2c01230 334fba0e09c2f155d41c9837eb92cdf5 722 SUPERFAMILY SSF48452 37 163 1.2E-18 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 VAPA_2c01230 334fba0e09c2f155d41c9837eb92cdf5 722 Gene3D G3DSA:3.40.50.2000 508 687 1.0E-141 T 12-10-2018 VAPA_2c01230 334fba0e09c2f155d41c9837eb92cdf5 722 Gene3D G3DSA:3.40.50.11380 346 694 1.0E-141 T 12-10-2018 VAPA_2c01230 334fba0e09c2f155d41c9837eb92cdf5 722 SUPERFAMILY SSF48452 122 258 5.2E-31 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 VAPA_2c12810 3b607d989b57dd69e42f1e9db8562da6 277 Pfam PF01695 IstB-like ATP binding protein 87 158 1.7E-11 T 12-10-2018 IPR002611 IstB-like ATP-binding protein GO:0005524 VAPA_2c12810 3b607d989b57dd69e42f1e9db8562da6 277 Gene3D G3DSA:3.40.50.300 76 175 2.4E-7 T 12-10-2018 VAPA_1c06920 8a79383ee9ee466a0bd12b4fcf786833 313 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 50 61 3.9E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c06920 8a79383ee9ee466a0bd12b4fcf786833 313 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 50 3.9E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c06920 8a79383ee9ee466a0bd12b4fcf786833 313 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 40 3.9E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c06920 8a79383ee9ee466a0bd12b4fcf786833 313 Gene3D G3DSA:3.40.190.10 182 284 1.7E-33 T 12-10-2018 VAPA_1c06920 8a79383ee9ee466a0bd12b4fcf786833 313 Gene3D G3DSA:1.10.10.10 11 101 1.8E-20 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c06920 8a79383ee9ee466a0bd12b4fcf786833 313 Pfam PF03466 LysR substrate binding domain 98 310 1.1E-32 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_1c06920 8a79383ee9ee466a0bd12b4fcf786833 313 Gene3D G3DSA:3.40.190.10 105 296 1.7E-33 T 12-10-2018 VAPA_1c06920 8a79383ee9ee466a0bd12b4fcf786833 313 SUPERFAMILY SSF53850 100 311 3.95E-33 T 12-10-2018 VAPA_1c06920 8a79383ee9ee466a0bd12b4fcf786833 313 SUPERFAMILY SSF46785 11 114 4.99E-17 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c06920 8a79383ee9ee466a0bd12b4fcf786833 313 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 14 73 6.4E-17 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c49600 b4b99bce1bf1024273be8f7edfd22a20 232 SUPERFAMILY SSF46689 39 112 4.77E-18 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 VAPA_1c49600 b4b99bce1bf1024273be8f7edfd22a20 232 Gene3D G3DSA:1.10.357.10 30 232 2.3E-41 T 12-10-2018 VAPA_1c49600 b4b99bce1bf1024273be8f7edfd22a20 232 Pfam PF00440 Bacterial regulatory proteins, tetR family 48 92 7.1E-18 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 VAPA_1c49600 b4b99bce1bf1024273be8f7edfd22a20 232 SUPERFAMILY SSF48498 122 229 3.22E-8 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily VAPA_1c49600 b4b99bce1bf1024273be8f7edfd22a20 232 ProSitePatterns PS01081 TetR-type HTH domain signature. 60 90 - T 12-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site VAPA_1c49600 b4b99bce1bf1024273be8f7edfd22a20 232 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 48 61 5.6E-10 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 VAPA_1c49600 b4b99bce1bf1024273be8f7edfd22a20 232 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 69 92 5.6E-10 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 VAPA_1c15470 d9e57781b963155b5a6ae4771a1d7a32 104 ProDom PD004231 RIBOSOMAL S20 30S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN S20P SUBUNIT CHLOROPLAST DIRECT 21 89 2.0E-29 T 12-10-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 VAPA_1c15470 d9e57781b963155b5a6ae4771a1d7a32 104 Hamap MF_00500 30S ribosomal protein S20 [rpsT]. 1 94 16.115 T 12-10-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 VAPA_1c15470 d9e57781b963155b5a6ae4771a1d7a32 104 Pfam PF01649 Ribosomal protein S20 14 93 5.7E-24 T 12-10-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 VAPA_1c15470 d9e57781b963155b5a6ae4771a1d7a32 104 Gene3D G3DSA:1.20.58.110 11 96 4.2E-24 T 12-10-2018 IPR036510 Ribosomal protein S20 superfamily GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 VAPA_1c15470 d9e57781b963155b5a6ae4771a1d7a32 104 SUPERFAMILY SSF46992 14 95 8.76E-27 T 12-10-2018 IPR036510 Ribosomal protein S20 superfamily GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 VAPA_1c15470 d9e57781b963155b5a6ae4771a1d7a32 104 TIGRFAM TIGR00029 S20: ribosomal protein bS20 14 95 2.8E-23 T 12-10-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 VAPA_1c15330 dbbe5625fc545bc759789120383bc072 955 SUPERFAMILY SSF52016 691 953 3.34E-79 T 12-10-2018 VAPA_1c15330 dbbe5625fc545bc759789120383bc072 955 Gene3D G3DSA:1.10.1440.20 647 707 3.0E-10 T 12-10-2018 VAPA_1c15330 dbbe5625fc545bc759789120383bc072 955 Pfam PF00330 Aconitase family (aconitate hydratase) 73 617 2.8E-173 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 VAPA_1c15330 dbbe5625fc545bc759789120383bc072 955 Gene3D G3DSA:3.20.19.10 711 954 1.0E-100 T 12-10-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel KEGG: 00290+4.2.1.33 VAPA_1c15330 dbbe5625fc545bc759789120383bc072 955 ProSitePatterns PS00450 Aconitase family signature 1. 482 498 - T 12-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 VAPA_1c15330 dbbe5625fc545bc759789120383bc072 955 Gene3D G3DSA:3.30.499.10 446 645 2.0E-86 T 12-10-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 KEGG: 00290+4.2.1.33 VAPA_1c15330 dbbe5625fc545bc759789120383bc072 955 Pfam PF00694 Aconitase C-terminal domain 749 880 1.5E-38 T 12-10-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain KEGG: 00290+4.2.1.33 VAPA_1c15330 dbbe5625fc545bc759789120383bc072 955 Gene3D G3DSA:3.30.499.20 6 379 2.6E-156 T 12-10-2018 VAPA_1c15330 dbbe5625fc545bc759789120383bc072 955 ProSitePatterns PS01244 Aconitase family signature 2. 548 561 - T 12-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 VAPA_1c15330 dbbe5625fc545bc759789120383bc072 955 SUPERFAMILY SSF53732 18 673 5.23E-207 T 12-10-2018 IPR036008 Aconitase, iron-sulfur domain KEGG: 00290+4.2.1.33 VAPA_1c15330 dbbe5625fc545bc759789120383bc072 955 PRINTS PR00415 Aconitase family signature 486 497 3.7E-39 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 VAPA_1c15330 dbbe5625fc545bc759789120383bc072 955 PRINTS PR00415 Aconitase family signature 174 182 3.7E-39 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 VAPA_1c15330 dbbe5625fc545bc759789120383bc072 955 PRINTS PR00415 Aconitase family signature 150 163 3.7E-39 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 VAPA_1c15330 dbbe5625fc545bc759789120383bc072 955 PRINTS PR00415 Aconitase family signature 209 222 3.7E-39 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 VAPA_1c15330 dbbe5625fc545bc759789120383bc072 955 PRINTS PR00415 Aconitase family signature 223 238 3.7E-39 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 VAPA_1c15330 dbbe5625fc545bc759789120383bc072 955 PRINTS PR00415 Aconitase family signature 299 312 3.7E-39 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 VAPA_1c15330 dbbe5625fc545bc759789120383bc072 955 PRINTS PR00415 Aconitase family signature 285 298 3.7E-39 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 VAPA_1c15330 dbbe5625fc545bc759789120383bc072 955 PRINTS PR00415 Aconitase family signature 379 393 3.7E-39 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 VAPA_1c15330 dbbe5625fc545bc759789120383bc072 955 PRINTS PR00415 Aconitase family signature 548 561 3.7E-39 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 VAPA_1c53000 dc3303682425ba173a9b4597aa4b85a2 112 Pfam PF05437 Branched-chain amino acid transport protein (AzlD) 10 106 2.1E-28 T 12-10-2018 IPR008407 Branched-chain amino acid transport, AzlD VAPA_1c29440 e04e4a56d80a3451c978abe64ef68004 180 SUPERFAMILY SSF111384 31 170 6.02E-34 T 12-10-2018 VAPA_1c29440 e04e4a56d80a3451c978abe64ef68004 180 Gene3D G3DSA:3.30.910.20 30 170 2.9E-37 T 12-10-2018 IPR024930 Skp domain superfamily VAPA_1c29440 e04e4a56d80a3451c978abe64ef68004 180 Pfam PF03938 Outer membrane protein (OmpH-like) 17 169 8.2E-36 T 12-10-2018 IPR005632 Chaperone protein Skp GO:0051082 VAPA_1c29440 e04e4a56d80a3451c978abe64ef68004 180 SMART SM00935 17 170 2.0E-58 T 12-10-2018 IPR005632 Chaperone protein Skp GO:0051082 VAPA_1c29440 e04e4a56d80a3451c978abe64ef68004 180 PIRSF PIRSF002094 1 173 2.8E-48 T 12-10-2018 IPR005632 Chaperone protein Skp GO:0051082 VAPA_1c29420 761658e8913c17762141631b36f3c339 149 SUPERFAMILY SSF54637 4 146 1.59E-50 T 12-10-2018 IPR029069 HotDog domain superfamily VAPA_1c29420 761658e8913c17762141631b36f3c339 149 Gene3D G3DSA:3.10.129.10 1 148 2.8E-61 T 12-10-2018 VAPA_1c29420 761658e8913c17762141631b36f3c339 149 TIGRFAM TIGR01750 fabZ: beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ 5 145 4.8E-60 T 12-10-2018 IPR010084 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ GO:0005737|GO:0006633|GO:0016836 KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 VAPA_1c29420 761658e8913c17762141631b36f3c339 149 Hamap MF_00406 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ [fabZ]. 5 147 36.132 T 12-10-2018 IPR010084 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ GO:0005737|GO:0006633|GO:0016836 KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 VAPA_1c29420 761658e8913c17762141631b36f3c339 149 Pfam PF07977 FabA-like domain 14 139 6.2E-38 T 12-10-2018 IPR013114 Beta-hydroxydecanoyl thiol ester dehydrase, FabA/FabZ KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 VAPA_1c10670 44552708d65e599b27392d7d804a9f40 312 Gene3D G3DSA:1.10.10.10 1 86 1.0E-23 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c10670 44552708d65e599b27392d7d804a9f40 312 SUPERFAMILY SSF53850 92 297 4.19E-43 T 12-10-2018 VAPA_1c10670 44552708d65e599b27392d7d804a9f40 312 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 4.2E-19 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c10670 44552708d65e599b27392d7d804a9f40 312 Pfam PF03466 LysR substrate binding domain 91 291 1.5E-44 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_1c10670 44552708d65e599b27392d7d804a9f40 312 SUPERFAMILY SSF46785 2 112 3.08E-21 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c10670 44552708d65e599b27392d7d804a9f40 312 Gene3D G3DSA:3.40.190.290 92 299 6.9E-48 T 12-10-2018 VAPA_2c06090 98feef447b5c5e1a3b615afbd9da15f6 619 SUPERFAMILY SSF51905 4 221 3.24E-9 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_2c06090 98feef447b5c5e1a3b615afbd9da15f6 619 Pfam PF13454 FAD-NAD(P)-binding 6 167 2.4E-33 T 12-10-2018 IPR038732 FAD-dependent urate hydroxylase HpyO, FAD/NAD(P)-binding domain VAPA_2c05940 2771c8add16b1434f25c733b1a7a6c35 455 Pfam PF00072 Response regulator receiver domain 4 109 4.5E-25 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_2c05940 2771c8add16b1434f25c733b1a7a6c35 455 Pfam PF00158 Sigma-54 interaction domain 140 304 3.7E-69 T 12-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 VAPA_2c05940 2771c8add16b1434f25c733b1a7a6c35 455 Gene3D G3DSA:3.40.50.2300 1 130 3.2E-34 T 12-10-2018 VAPA_2c05940 2771c8add16b1434f25c733b1a7a6c35 455 Pfam PF02954 Bacterial regulatory protein, Fis family 415 439 7.4E-6 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 VAPA_2c05940 2771c8add16b1434f25c733b1a7a6c35 455 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 162 175 - T 12-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 VAPA_2c05940 2771c8add16b1434f25c733b1a7a6c35 455 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 351 360 - T 12-10-2018 IPR025944 Sigma-54 interaction domain, conserved site VAPA_2c05940 2771c8add16b1434f25c733b1a7a6c35 455 SMART SM00382 158 301 1.3E-15 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_2c05940 2771c8add16b1434f25c733b1a7a6c35 455 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 414 431 2.7E-7 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 VAPA_2c05940 2771c8add16b1434f25c733b1a7a6c35 455 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 431 451 2.7E-7 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 VAPA_2c05940 2771c8add16b1434f25c733b1a7a6c35 455 SUPERFAMILY SSF52172 2 181 1.29E-40 T 12-10-2018 IPR011006 CheY-like superfamily VAPA_2c05940 2771c8add16b1434f25c733b1a7a6c35 455 Gene3D G3DSA:3.40.50.300 131 308 2.0E-65 T 12-10-2018 VAPA_2c05940 2771c8add16b1434f25c733b1a7a6c35 455 SUPERFAMILY SSF52540 138 374 3.47E-71 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_2c05940 2771c8add16b1434f25c733b1a7a6c35 455 SUPERFAMILY SSF46689 351 450 3.94E-7 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 VAPA_2c05940 2771c8add16b1434f25c733b1a7a6c35 455 Gene3D G3DSA:1.10.10.60 391 452 3.9E-7 T 12-10-2018 VAPA_2c05940 2771c8add16b1434f25c733b1a7a6c35 455 Gene3D G3DSA:1.10.8.60 309 385 6.8E-20 T 12-10-2018 VAPA_2c05940 2771c8add16b1434f25c733b1a7a6c35 455 SMART SM00448 2 111 8.1E-33 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_1c01460 c336758552a4b4302d13cd2d420e77a6 384 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 48 66 7.5E-8 T 12-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 VAPA_1c01460 c336758552a4b4302d13cd2d420e77a6 384 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 29 45 7.5E-8 T 12-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 VAPA_1c01460 c336758552a4b4302d13cd2d420e77a6 384 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 7 23 7.5E-8 T 12-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 VAPA_1c01460 c336758552a4b4302d13cd2d420e77a6 384 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 237 255 7.5E-8 T 12-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 VAPA_1c01460 c336758552a4b4302d13cd2d420e77a6 384 Gene3D G3DSA:3.40.50.2300 122 357 3.8E-133 T 12-10-2018 VAPA_1c01460 c336758552a4b4302d13cd2d420e77a6 384 Pfam PF13433 Periplasmic binding protein domain 7 370 3.1E-145 T 12-10-2018 VAPA_1c01460 c336758552a4b4302d13cd2d420e77a6 384 Gene3D G3DSA:3.40.50.2300 9 338 3.8E-133 T 12-10-2018 VAPA_1c01460 c336758552a4b4302d13cd2d420e77a6 384 SUPERFAMILY SSF53822 6 375 5.89E-93 T 12-10-2018 IPR028082 Periplasmic binding protein-like I VAPA_1c04710 35986d456161ac1938f4064fcef933f2 559 Gene3D G3DSA:3.30.300.310 462 559 4.9E-30 T 12-10-2018 VAPA_1c04710 35986d456161ac1938f4064fcef933f2 559 Pfam PF13193 AMP-binding enzyme C-terminal domain 474 548 2.4E-16 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain VAPA_1c04710 35986d456161ac1938f4064fcef933f2 559 ProSitePatterns PS00455 Putative AMP-binding domain signature. 211 222 - T 12-10-2018 IPR020845 AMP-binding, conserved site VAPA_1c04710 35986d456161ac1938f4064fcef933f2 559 SUPERFAMILY SSF56801 21 557 2.09E-147 T 12-10-2018 VAPA_1c04710 35986d456161ac1938f4064fcef933f2 559 Pfam PF00501 AMP-binding enzyme 31 465 9.2E-103 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 VAPA_1c04710 35986d456161ac1938f4064fcef933f2 559 Gene3D G3DSA:3.40.50.12780 13 461 7.4E-113 T 12-10-2018 VAPA_2c09300 6918cbcc49af7ff1807457b7ac58d116 190 SUPERFAMILY SSF53098 34 162 2.47E-8 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily VAPA_2c09300 6918cbcc49af7ff1807457b7ac58d116 190 Pfam PF13358 DDE superfamily endonuclease 18 147 6.3E-22 T 12-10-2018 IPR038717 Tc1-like transposase, DDE domain VAPA_2c04610 1bafcda5af227dbb9aaa42dc71bf9dbb 150 Pfam PF02566 OsmC-like protein 39 138 1.3E-11 T 12-10-2018 IPR003718 OsmC/Ohr family VAPA_2c04610 1bafcda5af227dbb9aaa42dc71bf9dbb 150 Gene3D G3DSA:3.30.300.20 5 138 7.3E-21 T 12-10-2018 IPR015946 K homology domain-like, alpha/beta VAPA_2c04610 1bafcda5af227dbb9aaa42dc71bf9dbb 150 SUPERFAMILY SSF82784 25 137 5.37E-20 T 12-10-2018 IPR036102 OsmC/Ohr superfamily VAPA_1c02120 31d154271fca7471f3bba6656f2187f5 254 SUPERFAMILY SSF48498 96 219 1.72E-33 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily VAPA_1c02120 31d154271fca7471f3bba6656f2187f5 254 Pfam PF00440 Bacterial regulatory proteins, tetR family 28 74 9.3E-14 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 VAPA_1c02120 31d154271fca7471f3bba6656f2187f5 254 Gene3D G3DSA:1.10.357.10 23 228 3.0E-58 T 12-10-2018 VAPA_1c02120 31d154271fca7471f3bba6656f2187f5 254 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 28 41 1.6E-6 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 VAPA_1c02120 31d154271fca7471f3bba6656f2187f5 254 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 49 72 1.6E-6 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 VAPA_1c02120 31d154271fca7471f3bba6656f2187f5 254 SUPERFAMILY SSF46689 16 99 6.16E-18 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 VAPA_1c36500 21822e6e38951ba4971adc9a6a83d289 413 Gene3D G3DSA:1.10.8.260 283 342 2.4E-112 T 12-10-2018 IPR023166 HI0933-like insert domain superfamily VAPA_1c36500 21822e6e38951ba4971adc9a6a83d289 413 Pfam PF03486 HI0933-like protein 10 411 2.0E-128 T 12-10-2018 VAPA_1c36500 21822e6e38951ba4971adc9a6a83d289 413 SUPERFAMILY SSF160996 207 360 3.14E-37 T 12-10-2018 VAPA_1c36500 21822e6e38951ba4971adc9a6a83d289 413 SUPERFAMILY SSF51905 10 412 4.01E-45 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c36500 21822e6e38951ba4971adc9a6a83d289 413 TIGRFAM TIGR00275 TIGR00275: flavoprotein, HI0933 family 12 410 1.3E-109 T 12-10-2018 IPR004792 Conserved hypothetical protein CHP00275, flavoprotein HI0933-like VAPA_1c36500 21822e6e38951ba4971adc9a6a83d289 413 Gene3D G3DSA:2.40.30.10 206 359 2.4E-112 T 12-10-2018 VAPA_1c36500 21822e6e38951ba4971adc9a6a83d289 413 Gene3D G3DSA:3.50.50.60 13 407 2.4E-112 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c36500 21822e6e38951ba4971adc9a6a83d289 413 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 173 182 2.2E-8 T 12-10-2018 VAPA_1c36500 21822e6e38951ba4971adc9a6a83d289 413 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 381 388 2.2E-8 T 12-10-2018 VAPA_1c36500 21822e6e38951ba4971adc9a6a83d289 413 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 11 33 2.2E-8 T 12-10-2018 VAPA_1c36300 18ecf200f3c3ec19b3c98cc187985525 426 Pfam PF03861 ANTAR domain 361 411 7.9E-16 T 12-10-2018 IPR005561 ANTAR domain GO:0003723 VAPA_1c36300 18ecf200f3c3ec19b3c98cc187985525 426 Gene3D G3DSA:1.10.10.10 360 417 2.6E-16 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c36300 18ecf200f3c3ec19b3c98cc187985525 426 SUPERFAMILY SSF52172 339 411 7.95E-14 T 12-10-2018 IPR011006 CheY-like superfamily VAPA_1c36300 18ecf200f3c3ec19b3c98cc187985525 426 SMART SM01012 357 412 2.3E-19 T 12-10-2018 IPR005561 ANTAR domain GO:0003723 VAPA_1c36300 18ecf200f3c3ec19b3c98cc187985525 426 Pfam PF08376 Nitrate and nitrite sensing 35 284 4.7E-45 T 12-10-2018 IPR013587 Nitrate/nitrite sensing protein VAPA_1c16880 616e761377bbd6f405808e545d734d9d 165 SUPERFAMILY SSF47741 85 152 3.66E-32 T 12-10-2018 IPR036884 [2Fe-2S]-binding domain superfamily VAPA_1c16880 616e761377bbd6f405808e545d734d9d 165 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 39 47 - T 12-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 VAPA_1c16880 616e761377bbd6f405808e545d734d9d 165 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 5 57 1.3E-7 T 12-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 VAPA_1c16880 616e761377bbd6f405808e545d734d9d 165 Pfam PF01799 [2Fe-2S] binding domain 73 147 1.2E-30 T 12-10-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 VAPA_1c16880 616e761377bbd6f405808e545d734d9d 165 Gene3D G3DSA:1.10.150.120 75 164 5.1E-33 T 12-10-2018 VAPA_1c16880 616e761377bbd6f405808e545d734d9d 165 SUPERFAMILY SSF54292 2 78 6.29E-25 T 12-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 VAPA_1c16880 616e761377bbd6f405808e545d734d9d 165 Gene3D G3DSA:3.10.20.30 1 74 3.1E-29 T 12-10-2018 IPR012675 Beta-grasp domain superfamily VAPA_1c50910 cfe6cd2b0f82b71034c6e033e3212859 92 SUPERFAMILY SSF54570 3 84 6.93E-35 T 12-10-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VAPA_1c50910 cfe6cd2b0f82b71034c6e033e3212859 92 Pfam PF00203 Ribosomal protein S19 3 83 1.4E-36 T 12-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VAPA_1c50910 cfe6cd2b0f82b71034c6e033e3212859 92 TIGRFAM TIGR01050 rpsS_bact: ribosomal protein uS19 1 90 1.2E-44 T 12-10-2018 IPR005732 Ribosomal protein S19, bacterial-type GO:0003735|GO:0006412|GO:0015935 VAPA_1c50910 cfe6cd2b0f82b71034c6e033e3212859 92 Gene3D G3DSA:3.30.860.10 1 92 5.2E-42 T 12-10-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VAPA_1c50910 cfe6cd2b0f82b71034c6e033e3212859 92 PIRSF PIRSF002144 1 92 1.5E-32 T 12-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VAPA_1c50910 cfe6cd2b0f82b71034c6e033e3212859 92 Hamap MF_00531 30S ribosomal protein S19 [rpsS]. 1 89 25.133 T 12-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VAPA_1c50910 cfe6cd2b0f82b71034c6e033e3212859 92 PRINTS PR00975 Ribosomal protein S19 family signature 65 80 1.7E-24 T 12-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VAPA_1c50910 cfe6cd2b0f82b71034c6e033e3212859 92 PRINTS PR00975 Ribosomal protein S19 family signature 53 65 1.7E-24 T 12-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VAPA_1c50910 cfe6cd2b0f82b71034c6e033e3212859 92 PRINTS PR00975 Ribosomal protein S19 family signature 33 52 1.7E-24 T 12-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VAPA_1c50910 cfe6cd2b0f82b71034c6e033e3212859 92 ProSitePatterns PS00323 Ribosomal protein S19 signature. 53 77 - T 12-10-2018 IPR020934 Ribosomal protein S19 conserved site GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VAPA_2c07340 876570e1253ecace75e8cacc8ed7db5d 222 SUPERFAMILY SSF50891 93 217 6.07E-35 T 12-10-2018 IPR029000 Cyclophilin-like domain superfamily VAPA_2c07340 876570e1253ecace75e8cacc8ed7db5d 222 TIGRFAM TIGR00370 TIGR00370: sensor histidine kinase inhibitor, KipI family 11 215 1.2E-58 T 12-10-2018 IPR010016 KipI family KEGG: 00480+3.5.2.9|MetaCyc: PWY-4041|MetaCyc: PWY-7942 VAPA_2c07340 876570e1253ecace75e8cacc8ed7db5d 222 Gene3D G3DSA:2.40.100.10 91 220 5.9E-42 T 12-10-2018 IPR029000 Cyclophilin-like domain superfamily VAPA_2c07340 876570e1253ecace75e8cacc8ed7db5d 222 SUPERFAMILY SSF160467 8 98 2.48E-9 T 12-10-2018 VAPA_2c07340 876570e1253ecace75e8cacc8ed7db5d 222 Pfam PF02682 Carboxyltransferase domain, subdomain C and D 7 206 4.5E-56 T 12-10-2018 IPR003833 Carboxyltransferase domain, subdomain C and D VAPA_2c07340 876570e1253ecace75e8cacc8ed7db5d 222 SMART SM00796 6 207 4.7E-82 T 12-10-2018 IPR003833 Carboxyltransferase domain, subdomain C and D VAPA_1c09740 2c20d6f5da1f18a8bfdb242eb1956bdc 323 ProSitePatterns PS00843 D-alanine--D-alanine ligase signature 1. 70 81 - T 12-10-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 VAPA_1c09740 2c20d6f5da1f18a8bfdb242eb1956bdc 323 Gene3D G3DSA:3.30.1490.20 118 187 1.9E-73 T 12-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 VAPA_1c09740 2c20d6f5da1f18a8bfdb242eb1956bdc 323 Gene3D G3DSA:3.40.50.20 1 91 6.3E-32 T 12-10-2018 VAPA_1c09740 2c20d6f5da1f18a8bfdb242eb1956bdc 323 Hamap MF_00047 D-alanine--D-alanine ligase [ddl]. 10 315 34.716 T 12-10-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 VAPA_1c09740 2c20d6f5da1f18a8bfdb242eb1956bdc 323 PIRSF PIRSF039102 7 58 5.1E-8 T 12-10-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 VAPA_1c09740 2c20d6f5da1f18a8bfdb242eb1956bdc 323 PIRSF PIRSF039102 49 320 1.3E-86 T 12-10-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 VAPA_1c09740 2c20d6f5da1f18a8bfdb242eb1956bdc 323 SUPERFAMILY SSF52440 11 103 1.63E-29 T 12-10-2018 IPR016185 Pre-ATP-grasp domain superfamily VAPA_1c09740 2c20d6f5da1f18a8bfdb242eb1956bdc 323 TIGRFAM TIGR01205 D_ala_D_alaTIGR: D-alanine--D-alanine ligase 11 314 8.3E-98 T 12-10-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 VAPA_1c09740 2c20d6f5da1f18a8bfdb242eb1956bdc 323 Gene3D G3DSA:3.30.470.20 92 310 1.9E-73 T 12-10-2018 VAPA_1c09740 2c20d6f5da1f18a8bfdb242eb1956bdc 323 SUPERFAMILY SSF56059 103 317 2.83E-52 T 12-10-2018 VAPA_1c09740 2c20d6f5da1f18a8bfdb242eb1956bdc 323 ProSitePatterns PS00844 D-alanine--D-alanine ligase signature 2. 256 285 - T 12-10-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 VAPA_1c09740 2c20d6f5da1f18a8bfdb242eb1956bdc 323 Pfam PF07478 D-ala D-ala ligase C-terminus 110 310 7.2E-59 T 12-10-2018 IPR011095 D-alanine--D-alanine ligase, C-terminal GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 VAPA_1c09740 2c20d6f5da1f18a8bfdb242eb1956bdc 323 Pfam PF01820 D-ala D-ala ligase N-terminus 11 93 3.2E-17 T 12-10-2018 IPR011127 D-alanine--D-alanine ligase, N-terminal domain KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 VAPA_1c10680 62078af3fb19925cc76a2436ba1712d2 437 SUPERFAMILY SSF103473 25 435 5.36E-58 T 12-10-2018 IPR036259 MFS transporter superfamily VAPA_1c10680 62078af3fb19925cc76a2436ba1712d2 437 Gene3D G3DSA:1.20.1250.20 24 435 4.1E-56 T 12-10-2018 VAPA_1c10680 62078af3fb19925cc76a2436ba1712d2 437 Pfam PF07690 Major Facilitator Superfamily 34 399 4.5E-25 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 VAPA_1c30130 4b3a4a9c87879a98c1c4d187c8527c80 567 Gene3D G3DSA:2.40.128.600 368 457 2.5E-6 T 12-10-2018 VAPA_1c30130 4b3a4a9c87879a98c1c4d187c8527c80 567 Gene3D G3DSA:3.40.710.10 3 338 9.3E-94 T 12-10-2018 VAPA_1c30130 4b3a4a9c87879a98c1c4d187c8527c80 567 SUPERFAMILY SSF56601 2 340 1.71E-88 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like VAPA_1c30130 4b3a4a9c87879a98c1c4d187c8527c80 567 Pfam PF11954 Domain of unknown function (DUF3471) 374 470 4.3E-16 T 12-10-2018 IPR021860 Peptidase S12, Pab87-related, C-terminal VAPA_1c30130 4b3a4a9c87879a98c1c4d187c8527c80 567 Pfam PF00144 Beta-lactamase 5 329 1.3E-69 T 12-10-2018 IPR001466 Beta-lactamase-related VAPA_1c16940 b5a7df223381fca1bae3fa83b2b5a029 340 Pfam PF13478 XdhC Rossmann domain 171 313 7.8E-36 T 12-10-2018 IPR027051 XdhC Rossmann domain VAPA_1c16940 b5a7df223381fca1bae3fa83b2b5a029 340 Gene3D G3DSA:3.40.50.720 170 319 4.3E-41 T 12-10-2018 VAPA_1c16940 b5a7df223381fca1bae3fa83b2b5a029 340 Pfam PF02625 XdhC and CoxI family 15 73 1.3E-20 T 12-10-2018 IPR003777 XdhC- CoxI VAPA_1c35350 9216bed1096b7fbbc2ac314f53eb312e 665 Gene3D G3DSA:3.40.50.670 412 657 8.8E-79 T 12-10-2018 IPR013759 DNA topoisomerase, type IIA, subunit B, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 VAPA_1c35350 9216bed1096b7fbbc2ac314f53eb312e 665 Pfam PF00204 DNA gyrase B 235 407 1.1E-33 T 12-10-2018 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 VAPA_1c35350 9216bed1096b7fbbc2ac314f53eb312e 665 PRINTS PR01098 Topoisomerase IV subunit B signature 333 348 4.3E-40 T 12-10-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 VAPA_1c35350 9216bed1096b7fbbc2ac314f53eb312e 665 PRINTS PR01098 Topoisomerase IV subunit B signature 191 208 4.3E-40 T 12-10-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 VAPA_1c35350 9216bed1096b7fbbc2ac314f53eb312e 665 PRINTS PR01098 Topoisomerase IV subunit B signature 151 165 4.3E-40 T 12-10-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 VAPA_1c35350 9216bed1096b7fbbc2ac314f53eb312e 665 PRINTS PR01098 Topoisomerase IV subunit B signature 384 409 4.3E-40 T 12-10-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 VAPA_1c35350 9216bed1096b7fbbc2ac314f53eb312e 665 PRINTS PR01098 Topoisomerase IV subunit B signature 470 491 4.3E-40 T 12-10-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 VAPA_1c35350 9216bed1096b7fbbc2ac314f53eb312e 665 PRINTS PR01098 Topoisomerase IV subunit B signature 209 230 4.3E-40 T 12-10-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 VAPA_1c35350 9216bed1096b7fbbc2ac314f53eb312e 665 PRINTS PR01098 Topoisomerase IV subunit B signature 39 52 4.3E-40 T 12-10-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 VAPA_1c35350 9216bed1096b7fbbc2ac314f53eb312e 665 PRINTS PR01098 Topoisomerase IV subunit B signature 360 383 4.3E-40 T 12-10-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 VAPA_1c35350 9216bed1096b7fbbc2ac314f53eb312e 665 PRINTS PR01098 Topoisomerase IV subunit B signature 316 332 4.3E-40 T 12-10-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 VAPA_1c35350 9216bed1096b7fbbc2ac314f53eb312e 665 SUPERFAMILY SSF54211 235 409 8.54E-37 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold VAPA_1c35350 9216bed1096b7fbbc2ac314f53eb312e 665 SUPERFAMILY SSF55874 18 232 4.06E-56 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_1c35350 9216bed1096b7fbbc2ac314f53eb312e 665 PRINTS PR00418 DNA topoisomerase II family signature 79 92 1.6E-60 T 12-10-2018 VAPA_1c35350 9216bed1096b7fbbc2ac314f53eb312e 665 PRINTS PR00418 DNA topoisomerase II family signature 288 301 1.6E-60 T 12-10-2018 VAPA_1c35350 9216bed1096b7fbbc2ac314f53eb312e 665 PRINTS PR00418 DNA topoisomerase II family signature 543 555 1.6E-60 T 12-10-2018 VAPA_1c35350 9216bed1096b7fbbc2ac314f53eb312e 665 PRINTS PR00418 DNA topoisomerase II family signature 44 59 1.6E-60 T 12-10-2018 VAPA_1c35350 9216bed1096b7fbbc2ac314f53eb312e 665 PRINTS PR00418 DNA topoisomerase II family signature 505 521 1.6E-60 T 12-10-2018 VAPA_1c35350 9216bed1096b7fbbc2ac314f53eb312e 665 PRINTS PR00418 DNA topoisomerase II family signature 436 450 1.6E-60 T 12-10-2018 VAPA_1c35350 9216bed1096b7fbbc2ac314f53eb312e 665 PRINTS PR00418 DNA topoisomerase II family signature 523 540 1.6E-60 T 12-10-2018 VAPA_1c35350 9216bed1096b7fbbc2ac314f53eb312e 665 PRINTS PR00418 DNA topoisomerase II family signature 595 611 1.6E-60 T 12-10-2018 VAPA_1c35350 9216bed1096b7fbbc2ac314f53eb312e 665 PRINTS PR00418 DNA topoisomerase II family signature 125 139 1.6E-60 T 12-10-2018 VAPA_1c35350 9216bed1096b7fbbc2ac314f53eb312e 665 Pfam PF01751 Toprim domain 435 549 7.8E-12 T 12-10-2018 IPR006171 TOPRIM domain VAPA_1c35350 9216bed1096b7fbbc2ac314f53eb312e 665 Gene3D G3DSA:3.30.565.10 16 232 2.4E-68 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_1c35350 9216bed1096b7fbbc2ac314f53eb312e 665 SUPERFAMILY SSF56719 412 659 1.15E-71 T 12-10-2018 IPR013760 DNA topoisomerase, type IIA-like domain superfamily GO:0003918|GO:0005524 Reactome: R-HSA-4615885 VAPA_1c35350 9216bed1096b7fbbc2ac314f53eb312e 665 ProSitePatterns PS00177 DNA topoisomerase II signature. 438 446 - T 12-10-2018 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 VAPA_1c35350 9216bed1096b7fbbc2ac314f53eb312e 665 Gene3D G3DSA:3.30.230.10 233 411 3.6E-46 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup VAPA_1c35350 9216bed1096b7fbbc2ac314f53eb312e 665 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 46 188 4.9E-16 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase VAPA_1c35350 9216bed1096b7fbbc2ac314f53eb312e 665 SMART SM00433 46 659 8.4E-183 T 12-10-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 VAPA_1c35350 9216bed1096b7fbbc2ac314f53eb312e 665 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 592 655 8.0E-21 T 12-10-2018 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 VAPA_1c35350 9216bed1096b7fbbc2ac314f53eb312e 665 Hamap MF_00938 DNA topoisomerase 4 subunit B [parE]. 15 663 43.204 T 12-10-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 VAPA_1c35350 9216bed1096b7fbbc2ac314f53eb312e 665 SMART SM00387 40 190 1.6E-17 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase VAPA_1c05520 3962e72b925698e4518e7d4fe28e0903 597 SUPERFAMILY SSF55874 285 452 9.95E-35 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_1c05520 3962e72b925698e4518e7d4fe28e0903 597 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 336 448 4.3E-22 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase VAPA_1c05520 3962e72b925698e4518e7d4fe28e0903 597 SMART SM00388 227 296 1.8E-8 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 VAPA_1c05520 3962e72b925698e4518e7d4fe28e0903 597 Gene3D G3DSA:3.30.565.10 299 451 9.8E-32 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_1c05520 3962e72b925698e4518e7d4fe28e0903 597 Gene3D G3DSA:3.40.50.2300 472 595 2.6E-19 T 12-10-2018 VAPA_1c05520 3962e72b925698e4518e7d4fe28e0903 597 PRINTS PR00344 Bacterial sensor protein C-terminal signature 375 389 1.4E-9 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c05520 3962e72b925698e4518e7d4fe28e0903 597 PRINTS PR00344 Bacterial sensor protein C-terminal signature 410 428 1.4E-9 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c05520 3962e72b925698e4518e7d4fe28e0903 597 PRINTS PR00344 Bacterial sensor protein C-terminal signature 434 447 1.4E-9 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c05520 3962e72b925698e4518e7d4fe28e0903 597 SMART SM00448 476 587 2.4E-14 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_1c05520 3962e72b925698e4518e7d4fe28e0903 597 SUPERFAMILY SSF47384 219 295 4.71E-9 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 VAPA_1c05520 3962e72b925698e4518e7d4fe28e0903 597 SMART SM00387 335 450 4.7E-29 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase VAPA_1c05520 3962e72b925698e4518e7d4fe28e0903 597 Gene3D G3DSA:1.10.287.130 217 297 5.2E-9 T 12-10-2018 VAPA_1c05520 3962e72b925698e4518e7d4fe28e0903 597 SUPERFAMILY SSF52172 475 592 4.84E-21 T 12-10-2018 IPR011006 CheY-like superfamily VAPA_1c05520 3962e72b925698e4518e7d4fe28e0903 597 Pfam PF00512 His Kinase A (phospho-acceptor) domain 228 295 4.5E-7 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 VAPA_1c05520 3962e72b925698e4518e7d4fe28e0903 597 Pfam PF00072 Response regulator receiver domain 478 586 2.0E-14 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_1c09400 2a09eddb7876edf48ab4b774a386a167 400 Gene3D G3DSA:3.20.20.140 53 348 2.8E-108 T 12-10-2018 VAPA_1c09400 2a09eddb7876edf48ab4b774a386a167 400 Gene3D G3DSA:2.30.40.10 4 387 2.8E-108 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 VAPA_1c09400 2a09eddb7876edf48ab4b774a386a167 400 SUPERFAMILY SSF51338 3 391 7.21E-13 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 VAPA_1c09400 2a09eddb7876edf48ab4b774a386a167 400 SUPERFAMILY SSF51556 52 358 1.33E-68 T 12-10-2018 IPR032466 Metal-dependent hydrolase VAPA_1c09400 2a09eddb7876edf48ab4b774a386a167 400 Pfam PF07969 Amidohydrolase family 45 386 9.6E-23 T 12-10-2018 IPR013108 Amidohydrolase 3 VAPA_1c17090 248301d6bf73e8219d99b1490ad4fc1c 562 SUPERFAMILY SSF50249 347 438 3.51E-21 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold VAPA_1c17090 248301d6bf73e8219d99b1490ad4fc1c 562 SUPERFAMILY SSF50249 255 369 5.0E-26 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold VAPA_1c17090 248301d6bf73e8219d99b1490ad4fc1c 562 SUPERFAMILY SSF50249 1 111 3.5E-18 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold VAPA_1c17090 248301d6bf73e8219d99b1490ad4fc1c 562 SUPERFAMILY SSF50249 103 184 6.0E-13 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold VAPA_1c17090 248301d6bf73e8219d99b1490ad4fc1c 562 SUPERFAMILY SSF50249 189 274 6.29E-25 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold VAPA_1c17090 248301d6bf73e8219d99b1490ad4fc1c 562 SMART SM00316 449 520 3.3E-20 T 12-10-2018 IPR022967 RNA-binding domain, S1 VAPA_1c17090 248301d6bf73e8219d99b1490ad4fc1c 562 SMART SM00316 19 87 0.022 T 12-10-2018 IPR022967 RNA-binding domain, S1 VAPA_1c17090 248301d6bf73e8219d99b1490ad4fc1c 562 SMART SM00316 190 260 3.4E-28 T 12-10-2018 IPR022967 RNA-binding domain, S1 VAPA_1c17090 248301d6bf73e8219d99b1490ad4fc1c 562 SMART SM00316 103 171 9.9E-7 T 12-10-2018 IPR022967 RNA-binding domain, S1 VAPA_1c17090 248301d6bf73e8219d99b1490ad4fc1c 562 SMART SM00316 362 434 8.3E-21 T 12-10-2018 IPR022967 RNA-binding domain, S1 VAPA_1c17090 248301d6bf73e8219d99b1490ad4fc1c 562 SMART SM00316 275 347 7.1E-23 T 12-10-2018 IPR022967 RNA-binding domain, S1 VAPA_1c17090 248301d6bf73e8219d99b1490ad4fc1c 562 Gene3D G3DSA:2.40.50.140 445 527 1.2E-19 T 12-10-2018 VAPA_1c17090 248301d6bf73e8219d99b1490ad4fc1c 562 Gene3D G3DSA:2.40.50.140 183 264 6.2E-27 T 12-10-2018 VAPA_1c17090 248301d6bf73e8219d99b1490ad4fc1c 562 PRINTS PR00681 Ribosomal protein S1 signature 108 124 3.3E-78 T 12-10-2018 VAPA_1c17090 248301d6bf73e8219d99b1490ad4fc1c 562 PRINTS PR00681 Ribosomal protein S1 signature 21 39 3.3E-78 T 12-10-2018 VAPA_1c17090 248301d6bf73e8219d99b1490ad4fc1c 562 PRINTS PR00681 Ribosomal protein S1 signature 126 143 3.3E-78 T 12-10-2018 VAPA_1c17090 248301d6bf73e8219d99b1490ad4fc1c 562 PRINTS PR00681 Ribosomal protein S1 signature 212 233 3.3E-78 T 12-10-2018 VAPA_1c17090 248301d6bf73e8219d99b1490ad4fc1c 562 PRINTS PR00681 Ribosomal protein S1 signature 39 53 3.3E-78 T 12-10-2018 VAPA_1c17090 248301d6bf73e8219d99b1490ad4fc1c 562 PRINTS PR00681 Ribosomal protein S1 signature 330 348 3.3E-78 T 12-10-2018 VAPA_1c17090 248301d6bf73e8219d99b1490ad4fc1c 562 PRINTS PR00681 Ribosomal protein S1 signature 155 175 3.3E-78 T 12-10-2018 VAPA_1c17090 248301d6bf73e8219d99b1490ad4fc1c 562 PRINTS PR00681 Ribosomal protein S1 signature 84 103 3.3E-78 T 12-10-2018 VAPA_1c17090 248301d6bf73e8219d99b1490ad4fc1c 562 PRINTS PR00681 Ribosomal protein S1 signature 290 309 3.3E-78 T 12-10-2018 VAPA_1c17090 248301d6bf73e8219d99b1490ad4fc1c 562 TIGRFAM TIGR00717 rpsA: ribosomal protein bS1 3 520 3.8E-199 T 12-10-2018 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 VAPA_1c17090 248301d6bf73e8219d99b1490ad4fc1c 562 Pfam PF00575 S1 RNA binding domain 363 434 1.1E-18 T 12-10-2018 IPR003029 S1 domain GO:0003676 VAPA_1c17090 248301d6bf73e8219d99b1490ad4fc1c 562 Pfam PF00575 S1 RNA binding domain 282 347 1.5E-19 T 12-10-2018 IPR003029 S1 domain GO:0003676 VAPA_1c17090 248301d6bf73e8219d99b1490ad4fc1c 562 Pfam PF00575 S1 RNA binding domain 450 520 3.5E-16 T 12-10-2018 IPR003029 S1 domain GO:0003676 VAPA_1c17090 248301d6bf73e8219d99b1490ad4fc1c 562 Pfam PF00575 S1 RNA binding domain 19 85 3.8E-6 T 12-10-2018 IPR003029 S1 domain GO:0003676 VAPA_1c17090 248301d6bf73e8219d99b1490ad4fc1c 562 Pfam PF00575 S1 RNA binding domain 103 171 3.2E-9 T 12-10-2018 IPR003029 S1 domain GO:0003676 VAPA_1c17090 248301d6bf73e8219d99b1490ad4fc1c 562 Pfam PF00575 S1 RNA binding domain 189 260 1.0E-21 T 12-10-2018 IPR003029 S1 domain GO:0003676 VAPA_1c17090 248301d6bf73e8219d99b1490ad4fc1c 562 SUPERFAMILY SSF50249 435 528 1.94E-19 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold VAPA_1c17090 248301d6bf73e8219d99b1490ad4fc1c 562 Gene3D G3DSA:2.40.50.140 356 444 7.4E-24 T 12-10-2018 VAPA_1c17090 248301d6bf73e8219d99b1490ad4fc1c 562 Gene3D G3DSA:2.40.50.140 98 181 1.0E-6 T 12-10-2018 VAPA_1c17090 248301d6bf73e8219d99b1490ad4fc1c 562 PIRSF PIRSF002111 1 534 5.0E-206 T 12-10-2018 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 VAPA_1c17090 248301d6bf73e8219d99b1490ad4fc1c 562 Gene3D G3DSA:2.40.50.140 6 97 2.7E-15 T 12-10-2018 VAPA_1c17090 248301d6bf73e8219d99b1490ad4fc1c 562 Gene3D G3DSA:2.40.50.140 272 355 5.6E-27 T 12-10-2018 VAPA_1c23350 29f12acab912f13dc776b981bb1bb694 214 SUPERFAMILY SSF52833 81 153 4.95E-11 T 12-10-2018 IPR036249 Thioredoxin-like superfamily VAPA_1c23350 29f12acab912f13dc776b981bb1bb694 214 Gene3D G3DSA:3.40.30.10 71 154 2.8E-11 T 12-10-2018 VAPA_1c23350 29f12acab912f13dc776b981bb1bb694 214 Pfam PF13511 Domain of unknown function (DUF4124) 17 50 9.9E-8 T 12-10-2018 IPR025392 Domain of unknown function DUF4124 VAPA_1c23350 29f12acab912f13dc776b981bb1bb694 214 Pfam PF00462 Glutaredoxin 82 137 1.5E-7 T 12-10-2018 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 VAPA_1c28410 f3a61910c7c5593b641bd3b129d52250 288 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 44 5.2E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c28410 f3a61910c7c5593b641bd3b129d52250 288 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 23 34 5.2E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c28410 f3a61910c7c5593b641bd3b129d52250 288 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 44 55 5.2E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c28410 f3a61910c7c5593b641bd3b129d52250 288 Gene3D G3DSA:1.10.10.10 7 92 2.0E-19 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c28410 f3a61910c7c5593b641bd3b129d52250 288 Gene3D G3DSA:3.40.190.290 95 286 1.6E-23 T 12-10-2018 VAPA_1c28410 f3a61910c7c5593b641bd3b129d52250 288 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 9 67 2.1E-17 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c28410 f3a61910c7c5593b641bd3b129d52250 288 SUPERFAMILY SSF46785 3 116 3.56E-22 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c28410 f3a61910c7c5593b641bd3b129d52250 288 Pfam PF03466 LysR substrate binding domain 92 285 2.1E-27 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_1c28410 f3a61910c7c5593b641bd3b129d52250 288 SUPERFAMILY SSF53850 94 286 2.71E-30 T 12-10-2018 VAPA_1c17000 c8257e83843fddfc2b0df3f977925bef 983 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 62 113 3.3E-9 T 12-10-2018 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VAPA_1c17000 c8257e83843fddfc2b0df3f977925bef 983 Pfam PF13244 Domain of unknown function (DUF4040) 618 680 8.2E-19 T 12-10-2018 IPR025383 Domain of unknown function DUF4040 VAPA_1c17000 c8257e83843fddfc2b0df3f977925bef 983 Pfam PF04039 Domain related to MnhB subunit of Na+/H+ antiporter 823 944 4.5E-32 T 12-10-2018 IPR007182 Na+/H+ antiporter MnhB subunit-related protein VAPA_1c17000 c8257e83843fddfc2b0df3f977925bef 983 Pfam PF00361 Proton-conducting membrane transporter 126 409 4.1E-63 T 12-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VAPA_1c17000 c8257e83843fddfc2b0df3f977925bef 983 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 238 264 3.3E-36 T 12-10-2018 VAPA_1c17000 c8257e83843fddfc2b0df3f977925bef 983 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 75 100 3.3E-36 T 12-10-2018 VAPA_1c17000 c8257e83843fddfc2b0df3f977925bef 983 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 415 434 3.3E-36 T 12-10-2018 VAPA_1c17000 c8257e83843fddfc2b0df3f977925bef 983 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 306 318 3.3E-36 T 12-10-2018 VAPA_1c17000 c8257e83843fddfc2b0df3f977925bef 983 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 103 123 3.3E-36 T 12-10-2018 VAPA_1c17000 c8257e83843fddfc2b0df3f977925bef 983 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 150 171 3.3E-36 T 12-10-2018 VAPA_1c17000 c8257e83843fddfc2b0df3f977925bef 983 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 216 237 3.3E-36 T 12-10-2018 VAPA_1c12300 0a7963de5e2fc43ad4197b6d2f961b84 390 Gene3D G3DSA:3.40.50.300 2 98 6.0E-10 T 12-10-2018 VAPA_1c12300 0a7963de5e2fc43ad4197b6d2f961b84 390 Pfam PF13304 AAA domain, putative AbiEii toxin, Type IV TA system 195 351 1.2E-19 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 VAPA_1c12300 0a7963de5e2fc43ad4197b6d2f961b84 390 Gene3D G3DSA:3.40.50.300 239 372 2.3E-8 T 12-10-2018 VAPA_1c12300 0a7963de5e2fc43ad4197b6d2f961b84 390 PIRSF PIRSF029347 1 390 1.1E-150 T 12-10-2018 IPR014555 RecF-like VAPA_1c12300 0a7963de5e2fc43ad4197b6d2f961b84 390 SUPERFAMILY SSF52540 5 365 6.82E-22 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c12300 0a7963de5e2fc43ad4197b6d2f961b84 390 Pfam PF13175 AAA ATPase domain 3 46 1.6E-8 T 12-10-2018 VAPA_1c24820 20c40cc3ff4ff87515af81553f154ce3 383 Pfam PF06463 Molybdenum Cofactor Synthesis C 227 353 2.0E-37 T 12-10-2018 IPR010505 Molybdenum cofactor synthesis C-terminal GO:0006777|GO:0019008|GO:0051539 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 VAPA_1c24820 20c40cc3ff4ff87515af81553f154ce3 383 ProSitePatterns PS01305 moaA / nifB / pqqE family signature. 49 60 - T 12-10-2018 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site GO:0003824|GO:0046872|GO:0051539 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 VAPA_1c24820 20c40cc3ff4ff87515af81553f154ce3 383 SUPERFAMILY SSF102114 35 338 1.57E-71 T 12-10-2018 VAPA_1c24820 20c40cc3ff4ff87515af81553f154ce3 383 Pfam PF13353 4Fe-4S single cluster domain 50 142 8.1E-10 T 12-10-2018 VAPA_1c24820 20c40cc3ff4ff87515af81553f154ce3 383 SMART SM00729 43 260 9.8E-8 T 12-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 VAPA_1c24820 20c40cc3ff4ff87515af81553f154ce3 383 TIGRFAM TIGR02666 moaA: molybdenum cofactor biosynthesis protein A 34 383 4.8E-112 T 12-10-2018 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 VAPA_1c24820 20c40cc3ff4ff87515af81553f154ce3 383 Gene3D G3DSA:3.20.20.70 31 383 2.6E-92 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 VAPA_1c24820 20c40cc3ff4ff87515af81553f154ce3 383 Pfam PF04055 Radical SAM superfamily 47 216 5.8E-27 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 VAPA_1c24820 20c40cc3ff4ff87515af81553f154ce3 383 Hamap MF_01225_B GTP 3',8-cyclase [moaA]. 34 383 39.594 T 12-10-2018 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 VAPA_1c00370 ce23a147a6ca182ad50dc88785b938fb 468 PRINTS PR00344 Bacterial sensor protein C-terminal signature 424 442 1.4E-5 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c00370 ce23a147a6ca182ad50dc88785b938fb 468 PRINTS PR00344 Bacterial sensor protein C-terminal signature 390 404 1.4E-5 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c00370 ce23a147a6ca182ad50dc88785b938fb 468 Pfam PF00512 His Kinase A (phospho-acceptor) domain 249 312 2.5E-12 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 VAPA_1c00370 ce23a147a6ca182ad50dc88785b938fb 468 Gene3D G3DSA:1.10.287.130 199 315 6.6E-19 T 12-10-2018 VAPA_1c00370 ce23a147a6ca182ad50dc88785b938fb 468 SMART SM00388 248 313 1.1E-12 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 VAPA_1c00370 ce23a147a6ca182ad50dc88785b938fb 468 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 366 458 1.1E-14 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase VAPA_1c00370 ce23a147a6ca182ad50dc88785b938fb 468 Gene3D G3DSA:3.30.565.10 319 463 5.4E-21 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_1c00370 ce23a147a6ca182ad50dc88785b938fb 468 SUPERFAMILY SSF55874 302 460 2.88E-23 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_1c00370 ce23a147a6ca182ad50dc88785b938fb 468 Pfam PF08521 Two-component sensor kinase N-terminal 30 171 2.2E-24 T 12-10-2018 IPR013727 Two-component sensor kinase, N-terminal VAPA_1c00370 ce23a147a6ca182ad50dc88785b938fb 468 SUPERFAMILY SSF47384 231 310 4.32E-15 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 VAPA_1c00370 ce23a147a6ca182ad50dc88785b938fb 468 SMART SM00387 359 464 5.4E-19 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase VAPA_1c41540 ba1d89be1f4e9fb728ea904f493d9f0d 450 Pfam PF13685 Iron-containing alcohol dehydrogenase 23 290 1.2E-55 T 12-10-2018 IPR032837 Glycerol-1-phosphate dehydrogenase KEGG: 00564+1.1.1.261|MetaCyc: PWY-6349 VAPA_1c41540 ba1d89be1f4e9fb728ea904f493d9f0d 450 Gene3D G3DSA:3.40.50.1970 11 173 5.5E-27 T 12-10-2018 VAPA_1c41540 ba1d89be1f4e9fb728ea904f493d9f0d 450 SUPERFAMILY SSF56796 19 312 2.09E-38 T 12-10-2018 VAPA_1c46210 6e639518fcedffb3f79e67cff221eb9e 427 SUPERFAMILY SSF52172 17 137 2.77E-7 T 12-10-2018 IPR011006 CheY-like superfamily VAPA_1c46210 6e639518fcedffb3f79e67cff221eb9e 427 Pfam PF16968 Pilus assembly protein TadZ N-terminal 24 137 2.8E-6 T 12-10-2018 IPR031580 Pilus assembly protein TadZ, N-terminal VAPA_1c46210 6e639518fcedffb3f79e67cff221eb9e 427 SUPERFAMILY SSF52540 144 392 2.86E-21 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c46210 6e639518fcedffb3f79e67cff221eb9e 427 Gene3D G3DSA:3.40.50.2300 12 140 4.1E-20 T 12-10-2018 VAPA_1c46210 6e639518fcedffb3f79e67cff221eb9e 427 Gene3D G3DSA:3.40.50.300 144 393 1.2E-33 T 12-10-2018 VAPA_1c08730 10b8133fcadf80208e9a5cef7a14936a 799 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 8 190 6.4E-43 T 12-10-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 VAPA_1c08730 10b8133fcadf80208e9a5cef7a14936a 799 Pfam PF00378 Enoyl-CoA hydratase/isomerase 503 639 9.9E-19 T 12-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 VAPA_1c08730 10b8133fcadf80208e9a5cef7a14936a 799 Gene3D G3DSA:3.40.50.720 1 194 1.1E-55 T 12-10-2018 VAPA_1c08730 10b8133fcadf80208e9a5cef7a14936a 799 Gene3D G3DSA:1.10.1040.10 357 419 4.4E-5 T 12-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 VAPA_1c08730 10b8133fcadf80208e9a5cef7a14936a 799 SUPERFAMILY SSF48179 192 313 1.19E-18 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 VAPA_1c08730 10b8133fcadf80208e9a5cef7a14936a 799 SUPERFAMILY SSF51735 5 192 1.35E-41 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c08730 10b8133fcadf80208e9a5cef7a14936a 799 Gene3D G3DSA:3.90.226.10 484 697 4.5E-29 T 12-10-2018 VAPA_1c08730 10b8133fcadf80208e9a5cef7a14936a 799 Gene3D G3DSA:1.10.1040.10 195 304 2.5E-19 T 12-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 VAPA_1c08730 10b8133fcadf80208e9a5cef7a14936a 799 SUPERFAMILY SSF52096 482 795 1.99E-40 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily VAPA_1c08730 10b8133fcadf80208e9a5cef7a14936a 799 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 194 295 2.9E-12 T 12-10-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 VAPA_1c08730 10b8133fcadf80208e9a5cef7a14936a 799 SUPERFAMILY SSF48179 344 463 1.11E-20 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 VAPA_1c20400 a5cee0b6ea6c6766885d4a546d7afb94 156 Pfam PF00866 Ring hydroxylating beta subunit 17 149 1.7E-12 T 12-10-2018 IPR000391 Ring-hydroxylating dioxygenase beta subunit GO:0006725|GO:0055114 VAPA_1c20400 a5cee0b6ea6c6766885d4a546d7afb94 156 SUPERFAMILY SSF54427 2 156 5.35E-45 T 12-10-2018 IPR032710 NTF2-like domain superfamily VAPA_1c20400 a5cee0b6ea6c6766885d4a546d7afb94 156 Gene3D G3DSA:3.10.450.50 2 156 1.2E-37 T 12-10-2018 VAPA_1c07030 a5cee0b6ea6c6766885d4a546d7afb94 156 Pfam PF00866 Ring hydroxylating beta subunit 17 149 1.7E-12 T 12-10-2018 IPR000391 Ring-hydroxylating dioxygenase beta subunit GO:0006725|GO:0055114 VAPA_1c07030 a5cee0b6ea6c6766885d4a546d7afb94 156 SUPERFAMILY SSF54427 2 156 5.35E-45 T 12-10-2018 IPR032710 NTF2-like domain superfamily VAPA_1c07030 a5cee0b6ea6c6766885d4a546d7afb94 156 Gene3D G3DSA:3.10.450.50 2 156 1.2E-37 T 12-10-2018 VAPA_1c20800 f14f487d23911c8c8107e4dab3d4acd3 631 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 49 175 7.1E-28 T 12-10-2018 IPR007387 TRAP transporter, small membrane protein DctQ VAPA_1c20800 f14f487d23911c8c8107e4dab3d4acd3 631 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 215 624 2.8E-98 T 12-10-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit VAPA_1c20800 f14f487d23911c8c8107e4dab3d4acd3 631 TIGRFAM TIGR00786 dctM: TRAP transporter, DctM subunit 225 626 2.0E-87 T 12-10-2018 IPR004681 TRAP transporter large membrane protein DctM GO:0016021 VAPA_1c35620 88b892a1ff30432381a1431e539ba188 377 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 5 375 2.8E-128 T 12-10-2018 IPR002155 Thiolase GO:0016747 VAPA_1c35620 88b892a1ff30432381a1431e539ba188 377 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 85 103 - T 12-10-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0016747 VAPA_1c35620 88b892a1ff30432381a1431e539ba188 377 Gene3D G3DSA:3.40.47.10 5 260 1.7E-134 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 VAPA_1c35620 88b892a1ff30432381a1431e539ba188 377 SUPERFAMILY SSF53901 256 376 6.55E-43 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 VAPA_1c35620 88b892a1ff30432381a1431e539ba188 377 PIRSF PIRSF000429 1 377 4.9E-120 T 12-10-2018 IPR002155 Thiolase GO:0016747 VAPA_1c35620 88b892a1ff30432381a1431e539ba188 377 ProSitePatterns PS00737 Thiolases signature 2. 323 339 - T 12-10-2018 IPR020613 Thiolase, conserved site GO:0016747 VAPA_1c35620 88b892a1ff30432381a1431e539ba188 377 Pfam PF02803 Thiolase, C-terminal domain 255 376 2.5E-47 T 12-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 VAPA_1c35620 88b892a1ff30432381a1431e539ba188 377 Pfam PF00108 Thiolase, N-terminal domain 4 245 3.9E-63 T 12-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 VAPA_1c35620 88b892a1ff30432381a1431e539ba188 377 SUPERFAMILY SSF53901 3 250 7.07E-68 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 VAPA_1c35620 88b892a1ff30432381a1431e539ba188 377 Gene3D G3DSA:3.40.47.10 127 374 1.7E-134 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 VAPA_1c40820 521b20c478e54b20288db10ef82909fb 726 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 615 722 3.1E-18 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase VAPA_1c40820 521b20c478e54b20288db10ef82909fb 726 Gene3D G3DSA:3.30.565.10 573 725 5.8E-38 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_1c40820 521b20c478e54b20288db10ef82909fb 726 SUPERFAMILY SSF47384 492 569 4.12E-8 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 VAPA_1c40820 521b20c478e54b20288db10ef82909fb 726 PIRSF PIRSF036431 7 374 1.8E-77 T 12-10-2018 IPR017055 Signal transduction histidine kinase, DctB (C4-dicarboxylate transport system regulator) VAPA_1c40820 521b20c478e54b20288db10ef82909fb 726 PIRSF PIRSF036431 474 726 3.1E-63 T 12-10-2018 IPR017055 Signal transduction histidine kinase, DctB (C4-dicarboxylate transport system regulator) VAPA_1c40820 521b20c478e54b20288db10ef82909fb 726 SUPERFAMILY SSF103190 108 205 1.41E-14 T 12-10-2018 IPR029151 Periplasmic sensor-like domain superfamily VAPA_1c40820 521b20c478e54b20288db10ef82909fb 726 Gene3D G3DSA:3.30.450.20 357 507 5.2E-27 T 12-10-2018 VAPA_1c40820 521b20c478e54b20288db10ef82909fb 726 SUPERFAMILY SSF55785 374 486 3.32E-25 T 12-10-2018 IPR035965 PAS domain superfamily VAPA_1c40820 521b20c478e54b20288db10ef82909fb 726 SMART SM00387 615 725 3.5E-29 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase VAPA_1c40820 521b20c478e54b20288db10ef82909fb 726 Gene3D G3DSA:3.30.450.20 69 302 8.1E-64 T 12-10-2018 VAPA_1c40820 521b20c478e54b20288db10ef82909fb 726 Gene3D G3DSA:1.10.287.130 510 570 2.2E-14 T 12-10-2018 VAPA_1c40820 521b20c478e54b20288db10ef82909fb 726 Pfam PF00512 His Kinase A (phospho-acceptor) domain 505 569 1.1E-7 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 VAPA_1c40820 521b20c478e54b20288db10ef82909fb 726 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 366 487 7.6E-24 T 12-10-2018 IPR000014 PAS domain VAPA_1c40820 521b20c478e54b20288db10ef82909fb 726 PRINTS PR00344 Bacterial sensor protein C-terminal signature 709 722 1.8E-14 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c40820 521b20c478e54b20288db10ef82909fb 726 PRINTS PR00344 Bacterial sensor protein C-terminal signature 656 670 1.8E-14 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c40820 521b20c478e54b20288db10ef82909fb 726 PRINTS PR00344 Bacterial sensor protein C-terminal signature 685 703 1.8E-14 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c40820 521b20c478e54b20288db10ef82909fb 726 PRINTS PR00344 Bacterial sensor protein C-terminal signature 674 684 1.8E-14 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c40820 521b20c478e54b20288db10ef82909fb 726 SMART SM00091 367 434 1.6E-9 T 12-10-2018 IPR000014 PAS domain VAPA_1c40820 521b20c478e54b20288db10ef82909fb 726 Pfam PF02743 Cache domain 77 302 4.6E-14 T 12-10-2018 IPR033479 Double Cache domain 1 VAPA_1c40820 521b20c478e54b20288db10ef82909fb 726 Gene3D G3DSA:3.30.450.20 73 195 8.1E-64 T 12-10-2018 VAPA_1c40820 521b20c478e54b20288db10ef82909fb 726 Pfam PF00989 PAS fold 368 477 2.4E-13 T 12-10-2018 IPR013767 PAS fold GO:0006355 VAPA_1c40820 521b20c478e54b20288db10ef82909fb 726 SUPERFAMILY SSF55874 580 721 2.1E-35 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_1c40820 521b20c478e54b20288db10ef82909fb 726 SMART SM00388 505 573 9.3E-6 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 VAPA_1c52570 e7a6e9ed46de3249bf8b42b9900b377b 321 Pfam PF03466 LysR substrate binding domain 88 309 5.2E-42 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_1c52570 e7a6e9ed46de3249bf8b42b9900b377b 321 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 4.9E-19 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c52570 e7a6e9ed46de3249bf8b42b9900b377b 321 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.1E-7 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c52570 e7a6e9ed46de3249bf8b42b9900b377b 321 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.1E-7 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c52570 e7a6e9ed46de3249bf8b42b9900b377b 321 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.1E-7 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c52570 e7a6e9ed46de3249bf8b42b9900b377b 321 Gene3D G3DSA:3.40.190.10 92 307 2.3E-76 T 12-10-2018 VAPA_1c52570 e7a6e9ed46de3249bf8b42b9900b377b 321 Gene3D G3DSA:1.10.10.10 1 85 5.4E-30 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c52570 e7a6e9ed46de3249bf8b42b9900b377b 321 SUPERFAMILY SSF46785 1 84 6.68E-21 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c52570 e7a6e9ed46de3249bf8b42b9900b377b 321 Gene3D G3DSA:3.40.190.10 161 284 2.3E-76 T 12-10-2018 VAPA_1c52570 e7a6e9ed46de3249bf8b42b9900b377b 321 SUPERFAMILY SSF53850 88 311 2.31E-36 T 12-10-2018 VAPA_1c23160 f98309c0ad0efa5dda10b8a401666c49 618 Gene3D G3DSA:3.30.420.40 22 376 3.1E-109 T 12-10-2018 VAPA_1c23160 f98309c0ad0efa5dda10b8a401666c49 618 SUPERFAMILY SSF100920 385 539 1.57E-48 T 12-10-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain superfamily Reactome: R-HSA-3371453 VAPA_1c23160 f98309c0ad0efa5dda10b8a401666c49 618 Hamap MF_00679 Chaperone protein HscA [hscA]. 1 618 41.923 T 12-10-2018 IPR010236 ISC system FeS cluster assembly, HscA chaperone GO:0005524|GO:0006457|GO:0016226|GO:0016887|GO:0051082 VAPA_1c23160 f98309c0ad0efa5dda10b8a401666c49 618 TIGRFAM TIGR01991 HscA: Fe-S protein assembly chaperone HscA 21 616 5.6E-269 T 12-10-2018 IPR010236 ISC system FeS cluster assembly, HscA chaperone GO:0005524|GO:0006457|GO:0016226|GO:0016887|GO:0051082 VAPA_1c23160 f98309c0ad0efa5dda10b8a401666c49 618 SUPERFAMILY SSF53067 21 196 1.21E-48 T 12-10-2018 VAPA_1c23160 f98309c0ad0efa5dda10b8a401666c49 618 Gene3D G3DSA:1.20.1270.10 522 617 1.0E-27 T 12-10-2018 IPR029048 Heat shock protein 70kD, C-terminal domain superfamily Reactome: R-HSA-3371453 VAPA_1c23160 f98309c0ad0efa5dda10b8a401666c49 618 Pfam PF00012 Hsp70 protein 21 601 3.8E-176 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 VAPA_1c23160 f98309c0ad0efa5dda10b8a401666c49 618 SUPERFAMILY SSF53067 199 378 8.87E-51 T 12-10-2018 VAPA_1c23160 f98309c0ad0efa5dda10b8a401666c49 618 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 204 217 - T 12-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 VAPA_1c23160 f98309c0ad0efa5dda10b8a401666c49 618 ProSitePatterns PS00297 Heat shock hsp70 proteins family signature 1. 24 31 - T 12-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 VAPA_1c23160 f98309c0ad0efa5dda10b8a401666c49 618 Gene3D G3DSA:3.90.640.10 237 313 3.1E-109 T 12-10-2018 VAPA_1c23160 f98309c0ad0efa5dda10b8a401666c49 618 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 334 348 - T 12-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 VAPA_1c23160 f98309c0ad0efa5dda10b8a401666c49 618 SUPERFAMILY SSF100934 506 616 4.32E-35 T 12-10-2018 IPR029048 Heat shock protein 70kD, C-terminal domain superfamily Reactome: R-HSA-3371453 VAPA_1c23160 f98309c0ad0efa5dda10b8a401666c49 618 Gene3D G3DSA:3.30.420.40 193 363 3.1E-109 T 12-10-2018 VAPA_1c23160 f98309c0ad0efa5dda10b8a401666c49 618 PRINTS PR00301 70kDa heat shock protein signature 331 347 1.4E-56 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 VAPA_1c23160 f98309c0ad0efa5dda10b8a401666c49 618 PRINTS PR00301 70kDa heat shock protein signature 48 60 1.4E-56 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 VAPA_1c23160 f98309c0ad0efa5dda10b8a401666c49 618 PRINTS PR00301 70kDa heat shock protein signature 362 382 1.4E-56 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 VAPA_1c23160 f98309c0ad0efa5dda10b8a401666c49 618 PRINTS PR00301 70kDa heat shock protein signature 387 406 1.4E-56 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 VAPA_1c23160 f98309c0ad0efa5dda10b8a401666c49 618 PRINTS PR00301 70kDa heat shock protein signature 468 484 1.4E-56 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 VAPA_1c23160 f98309c0ad0efa5dda10b8a401666c49 618 PRINTS PR00301 70kDa heat shock protein signature 20 33 1.4E-56 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 VAPA_1c23160 f98309c0ad0efa5dda10b8a401666c49 618 PRINTS PR00301 70kDa heat shock protein signature 210 220 1.4E-56 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 VAPA_1c23160 f98309c0ad0efa5dda10b8a401666c49 618 PRINTS PR00301 70kDa heat shock protein signature 151 171 1.4E-56 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 VAPA_1c23160 f98309c0ad0efa5dda10b8a401666c49 618 Gene3D G3DSA:2.60.34.10 381 521 6.1E-47 T 12-10-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain superfamily Reactome: R-HSA-3371453 VAPA_2c03010 3d09fd8336a9ab36dd45db8cd2ed9f0d 475 Pfam PF00206 Lyase 14 343 6.4E-90 T 12-10-2018 IPR022761 Fumarate lyase, N-terminal VAPA_2c03010 3d09fd8336a9ab36dd45db8cd2ed9f0d 475 Pfam PF10415 Fumarase C C-terminus 409 461 1.6E-14 T 12-10-2018 IPR018951 Fumarase C, C-terminal GO:0006099|GO:0016829 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 VAPA_2c03010 3d09fd8336a9ab36dd45db8cd2ed9f0d 475 Gene3D G3DSA:1.10.40.30 409 463 2.8E-16 T 12-10-2018 VAPA_2c03010 3d09fd8336a9ab36dd45db8cd2ed9f0d 475 Gene3D G3DSA:1.10.275.10 6 139 3.8E-51 T 12-10-2018 IPR024083 Fumarase/histidase, N-terminal VAPA_2c03010 3d09fd8336a9ab36dd45db8cd2ed9f0d 475 PRINTS PR00145 Argininosuccinate lyase family signature 176 196 8.7E-5 T 12-10-2018 VAPA_2c03010 3d09fd8336a9ab36dd45db8cd2ed9f0d 475 PRINTS PR00145 Argininosuccinate lyase family signature 318 334 8.7E-5 T 12-10-2018 VAPA_2c03010 3d09fd8336a9ab36dd45db8cd2ed9f0d 475 PRINTS PR00145 Argininosuccinate lyase family signature 134 156 8.7E-5 T 12-10-2018 VAPA_2c03010 3d09fd8336a9ab36dd45db8cd2ed9f0d 475 PRINTS PR00149 Fumarate lyase superfamily signature 318 334 2.8E-31 T 12-10-2018 IPR000362 Fumarate lyase family VAPA_2c03010 3d09fd8336a9ab36dd45db8cd2ed9f0d 475 PRINTS PR00149 Fumarate lyase superfamily signature 272 299 2.8E-31 T 12-10-2018 IPR000362 Fumarate lyase family VAPA_2c03010 3d09fd8336a9ab36dd45db8cd2ed9f0d 475 PRINTS PR00149 Fumarate lyase superfamily signature 135 153 2.8E-31 T 12-10-2018 IPR000362 Fumarate lyase family VAPA_2c03010 3d09fd8336a9ab36dd45db8cd2ed9f0d 475 PRINTS PR00149 Fumarate lyase superfamily signature 181 199 2.8E-31 T 12-10-2018 IPR000362 Fumarate lyase family VAPA_2c03010 3d09fd8336a9ab36dd45db8cd2ed9f0d 475 Gene3D G3DSA:1.20.200.10 140 407 5.5E-100 T 12-10-2018 VAPA_2c03010 3d09fd8336a9ab36dd45db8cd2ed9f0d 475 Hamap MF_00743 Fumarate hydratase class II [fumC]. 5 463 70.94 T 12-10-2018 IPR005677 Fumarate hydratase, class II GO:0004333|GO:0006106|GO:0045239 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 VAPA_2c03010 3d09fd8336a9ab36dd45db8cd2ed9f0d 475 SUPERFAMILY SSF48557 5 458 1.57E-132 T 12-10-2018 IPR008948 L-Aspartase-like GO:0003824 VAPA_1c26990 be68a8942f090c9f27d31a74fe7dc969 126 Gene3D G3DSA:2.40.10.220 11 126 1.7E-41 T 12-10-2018 VAPA_1c26990 be68a8942f090c9f27d31a74fe7dc969 126 Pfam PF07238 PilZ domain 19 105 4.7E-7 T 12-10-2018 IPR009875 PilZ domain GO:0035438 VAPA_2c02220 1d858182f1140fcbf52747effab3568e 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 7.5E-10 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_2c02220 1d858182f1140fcbf52747effab3568e 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 7.5E-10 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_2c02220 1d858182f1140fcbf52747effab3568e 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 7.5E-10 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_2c02220 1d858182f1140fcbf52747effab3568e 294 Gene3D G3DSA:3.40.190.10 88 285 7.5E-54 T 12-10-2018 VAPA_2c02220 1d858182f1140fcbf52747effab3568e 294 Pfam PF03466 LysR substrate binding domain 87 288 4.2E-37 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_2c02220 1d858182f1140fcbf52747effab3568e 294 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 1.5E-21 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_2c02220 1d858182f1140fcbf52747effab3568e 294 SUPERFAMILY SSF46785 1 85 8.57E-22 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_2c02220 1d858182f1140fcbf52747effab3568e 294 SUPERFAMILY SSF53850 89 288 3.1E-31 T 12-10-2018 VAPA_2c02220 1d858182f1140fcbf52747effab3568e 294 Gene3D G3DSA:1.10.10.10 1 85 3.1E-28 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_2c02220 1d858182f1140fcbf52747effab3568e 294 Gene3D G3DSA:3.40.190.10 163 267 7.5E-54 T 12-10-2018 VAPA_1c25360 57df9db76731ac5e1c4d3cde620ea271 65 Pfam PF02597 ThiS family 7 65 2.6E-12 T 12-10-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 VAPA_1c25360 57df9db76731ac5e1c4d3cde620ea271 65 Gene3D G3DSA:3.10.20.30 1 65 1.1E-18 T 12-10-2018 IPR012675 Beta-grasp domain superfamily VAPA_1c25360 57df9db76731ac5e1c4d3cde620ea271 65 SUPERFAMILY SSF54285 1 65 4.97E-15 T 12-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp VAPA_1c25360 57df9db76731ac5e1c4d3cde620ea271 65 TIGRFAM TIGR01683 thiS: thiamine biosynthesis protein ThiS 3 65 9.9E-16 T 12-10-2018 IPR010035 ThiS, thiamine-biosynthesis VAPA_2c01480 1d68842cd33361b735a184af89f2c458 435 Gene3D G3DSA:1.10.700.10 306 419 3.8E-45 T 12-10-2018 IPR036622 Dioxygenase LigAB, LigA subunit superfamily VAPA_2c01480 1d68842cd33361b735a184af89f2c458 435 Pfam PF02900 Catalytic LigB subunit of aromatic ring-opening dioxygenase 7 269 5.4E-66 T 12-10-2018 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 VAPA_2c01480 1d68842cd33361b735a184af89f2c458 435 SUPERFAMILY SSF53213 2 294 3.4E-91 T 12-10-2018 VAPA_2c01480 1d68842cd33361b735a184af89f2c458 435 SUPERFAMILY SSF48076 293 417 2.62E-44 T 12-10-2018 IPR036622 Dioxygenase LigAB, LigA subunit superfamily VAPA_2c01480 1d68842cd33361b735a184af89f2c458 435 Gene3D G3DSA:3.40.830.10 3 305 1.2E-93 T 12-10-2018 VAPA_2c01480 1d68842cd33361b735a184af89f2c458 435 Pfam PF07746 Aromatic-ring-opening dioxygenase LigAB, LigA subunit 321 407 2.4E-34 T 12-10-2018 IPR011986 Extradiol ring-cleavage dioxygenase LigAB, LigA subunit VAPA_1c42290 c745e27ec9387c91e01d1ef77d7b2857 217 SUPERFAMILY SSF46689 2 67 4.22E-11 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 VAPA_1c42290 c745e27ec9387c91e01d1ef77d7b2857 217 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 47 2.2E-4 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 VAPA_1c42290 c745e27ec9387c91e01d1ef77d7b2857 217 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 75 210 1.6E-12 T 12-10-2018 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 VAPA_1c42290 c745e27ec9387c91e01d1ef77d7b2857 217 Gene3D G3DSA:1.10.357.10 69 215 1.1E-25 T 12-10-2018 VAPA_1c42290 c745e27ec9387c91e01d1ef77d7b2857 217 PRINTS PR00400 Tetracycline repressor protein signature 76 95 9.9E-5 T 12-10-2018 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 VAPA_1c42290 c745e27ec9387c91e01d1ef77d7b2857 217 PRINTS PR00400 Tetracycline repressor protein signature 24 47 9.9E-5 T 12-10-2018 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 VAPA_1c42290 c745e27ec9387c91e01d1ef77d7b2857 217 PRINTS PR00400 Tetracycline repressor protein signature 194 208 9.9E-5 T 12-10-2018 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 VAPA_1c42290 c745e27ec9387c91e01d1ef77d7b2857 217 SUPERFAMILY SSF48498 75 214 2.0E-25 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily VAPA_1c42290 c745e27ec9387c91e01d1ef77d7b2857 217 Gene3D G3DSA:1.10.10.60 2 66 5.2E-20 T 12-10-2018 VAPA_1c23580 4308bfb720a0bab1b3f6ba064af7b8ce 688 SUPERFAMILY SSF52540 25 642 1.6E-19 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c23580 4308bfb720a0bab1b3f6ba064af7b8ce 688 Gene3D G3DSA:3.40.50.300 26 260 5.5E-45 T 12-10-2018 VAPA_1c23580 4308bfb720a0bab1b3f6ba064af7b8ce 688 Gene3D G3DSA:3.40.50.300 478 678 2.0E-31 T 12-10-2018 VAPA_1c23580 4308bfb720a0bab1b3f6ba064af7b8ce 688 SMART SM00491 511 652 5.3E-31 T 12-10-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 VAPA_1c23580 4308bfb720a0bab1b3f6ba064af7b8ce 688 Pfam PF13307 Helicase C-terminal domain 501 665 7.6E-31 T 12-10-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 VAPA_1c50840 93cf34d96418581f4842da621ebee69e 195 SUPERFAMILY SSF55729 27 186 2.3E-21 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase VAPA_1c50840 93cf34d96418581f4842da621ebee69e 195 Pfam PF00583 Acetyltransferase (GNAT) family 96 174 1.5E-10 T 12-10-2018 IPR000182 GNAT domain VAPA_1c50840 93cf34d96418581f4842da621ebee69e 195 Gene3D G3DSA:3.40.630.30 20 195 2.6E-23 T 12-10-2018 VAPA_2c00950 63c118453460219ff16d95166888a1a0 418 Gene3D G3DSA:3.40.630.10 26 411 2.2E-110 T 12-10-2018 VAPA_2c00950 63c118453460219ff16d95166888a1a0 418 TIGRFAM TIGR01879 hydantase: amidase, hydantoinase/carbamoylase family 25 416 4.1E-81 T 12-10-2018 IPR010158 Amidase, carbamoylase-type GO:0016813 VAPA_2c00950 63c118453460219ff16d95166888a1a0 418 SUPERFAMILY SSF53187 24 417 4.19E-59 T 12-10-2018 VAPA_2c00950 63c118453460219ff16d95166888a1a0 418 PIRSF PIRSF001235 7 418 5.8E-102 T 12-10-2018 IPR010158 Amidase, carbamoylase-type GO:0016813 VAPA_2c00950 63c118453460219ff16d95166888a1a0 418 Gene3D G3DSA:3.30.70.360 216 336 2.2E-110 T 12-10-2018 VAPA_2c00950 63c118453460219ff16d95166888a1a0 418 SUPERFAMILY SSF55031 221 337 1.43E-16 T 12-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain VAPA_2c00950 63c118453460219ff16d95166888a1a0 418 Pfam PF01546 Peptidase family M20/M25/M40 78 412 2.2E-26 T 12-10-2018 IPR002933 Peptidase M20 GO:0016787 VAPA_1c02650 a994dd5879a8cb738d8b1bef6f1b80b2 761 Gene3D G3DSA:3.30.1920.30 245 307 3.0E-95 T 12-10-2018 VAPA_1c02650 a994dd5879a8cb738d8b1bef6f1b80b2 761 Gene3D G3DSA:2.40.50.230 375 477 4.9E-43 T 12-10-2018 IPR037026 Vgr protein, OB-fold domain superfamily VAPA_1c02650 a994dd5879a8cb738d8b1bef6f1b80b2 761 SUPERFAMILY SSF69255 384 472 4.71E-33 T 12-10-2018 VAPA_1c02650 a994dd5879a8cb738d8b1bef6f1b80b2 761 SUPERFAMILY SSF69349 462 630 4.47E-52 T 12-10-2018 VAPA_1c02650 a994dd5879a8cb738d8b1bef6f1b80b2 761 TIGRFAM TIGR01646 vgr_GE: Rhs element Vgr protein 31 526 8.4E-134 T 12-10-2018 IPR006533 Type VI secretion system, RhsGE-associated Vgr protein VAPA_1c02650 a994dd5879a8cb738d8b1bef6f1b80b2 761 Pfam PF06715 Gp5 C-terminal repeat (3 copies) 565 587 3.4E-7 T 12-10-2018 IPR010609 Gp5, C-terminal VAPA_1c02650 a994dd5879a8cb738d8b1bef6f1b80b2 761 Gene3D G3DSA:3.55.50.10 119 209 3.0E-95 T 12-10-2018 VAPA_1c02650 a994dd5879a8cb738d8b1bef6f1b80b2 761 SUPERFAMILY SSF69279 24 205 1.02E-48 T 12-10-2018 VAPA_1c02650 a994dd5879a8cb738d8b1bef6f1b80b2 761 Pfam PF05954 Phage late control gene D protein (GPD) 37 350 1.5E-84 T 12-10-2018 VAPA_1c02650 a994dd5879a8cb738d8b1bef6f1b80b2 761 SUPERFAMILY SSF69279 215 378 8.33E-32 T 12-10-2018 VAPA_1c02650 a994dd5879a8cb738d8b1bef6f1b80b2 761 TIGRFAM TIGR03361 VI_Rhs_Vgr: type VI secretion system Vgr family protein 26 544 1.8E-164 T 12-10-2018 IPR017847 Type VI secretion system, RhsGE-associated Vgr family subset VAPA_1c02650 a994dd5879a8cb738d8b1bef6f1b80b2 761 SUPERFAMILY SSF69349 599 743 2.67E-16 T 12-10-2018 VAPA_1c02650 a994dd5879a8cb738d8b1bef6f1b80b2 761 Gene3D G3DSA:2.30.110.50 32 350 3.0E-95 T 12-10-2018 VAPA_1c46650 7be1a72bff9cdd625606997ca266d034 612 SUPERFAMILY SSF52518 48 221 7.85E-45 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold VAPA_1c46650 7be1a72bff9cdd625606997ca266d034 612 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 440 584 1.2E-25 T 12-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 VAPA_1c46650 7be1a72bff9cdd625606997ca266d034 612 Gene3D G3DSA:3.40.50.970 395 610 1.9E-58 T 12-10-2018 VAPA_1c46650 7be1a72bff9cdd625606997ca266d034 612 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 242 374 1.4E-31 T 12-10-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 VAPA_1c46650 7be1a72bff9cdd625606997ca266d034 612 Gene3D G3DSA:3.40.50.970 42 233 1.2E-61 T 12-10-2018 VAPA_1c46650 7be1a72bff9cdd625606997ca266d034 612 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 51 219 5.1E-47 T 12-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 VAPA_1c46650 7be1a72bff9cdd625606997ca266d034 612 SUPERFAMILY SSF52467 236 401 2.66E-37 T 12-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily VAPA_1c46650 7be1a72bff9cdd625606997ca266d034 612 SUPERFAMILY SSF52518 414 591 3.87E-42 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold VAPA_1c46650 7be1a72bff9cdd625606997ca266d034 612 Gene3D G3DSA:3.40.50.1220 234 394 9.3E-42 T 12-10-2018 VAPA_1c46650 7be1a72bff9cdd625606997ca266d034 612 TIGRFAM TIGR03254 oxalate_oxc: oxalyl-CoA decarboxylase 48 603 1.2E-302 T 12-10-2018 IPR017660 Oxalyl-CoA decarboxylase GO:0008949|GO:0030976|GO:0033611|GO:0046872 KEGG: 00630+4.1.1.8|MetaCyc: PWY-6695|MetaCyc: PWY-6696|MetaCyc: PWY-7985 VAPA_1c08840 cc32e481d0501e973c453fe91fdd97a8 312 SUPERFAMILY SSF52283 4 136 1.15E-24 T 12-10-2018 VAPA_1c08840 cc32e481d0501e973c453fe91fdd97a8 312 Gene3D G3DSA:3.40.50.720 16 306 9.8E-98 T 12-10-2018 VAPA_1c08840 cc32e481d0501e973c453fe91fdd97a8 312 Gene3D G3DSA:3.40.50.720 102 284 9.8E-98 T 12-10-2018 VAPA_1c08840 cc32e481d0501e973c453fe91fdd97a8 312 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 111 281 1.3E-51 T 12-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 VAPA_1c08840 cc32e481d0501e973c453fe91fdd97a8 312 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 11 306 7.3E-13 T 12-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 VAPA_1c08840 cc32e481d0501e973c453fe91fdd97a8 312 SUPERFAMILY SSF51735 101 282 9.73E-54 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c06580 c06b821a500eafe7147af1d104381b84 289 Pfam PF09339 IclR helix-turn-helix domain 23 72 4.4E-10 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 VAPA_1c06580 c06b821a500eafe7147af1d104381b84 289 Pfam PF01614 Bacterial transcriptional regulator 142 259 1.6E-10 T 12-10-2018 IPR014757 Transcription regulator IclR, C-terminal VAPA_1c06580 c06b821a500eafe7147af1d104381b84 289 Gene3D G3DSA:3.30.450.40 95 267 1.8E-24 T 12-10-2018 IPR029016 GAF-like domain superfamily VAPA_1c06580 c06b821a500eafe7147af1d104381b84 289 SMART SM00346 21 110 4.7E-8 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 VAPA_1c06580 c06b821a500eafe7147af1d104381b84 289 SUPERFAMILY SSF55781 85 264 4.97E-28 T 12-10-2018 VAPA_1c06580 c06b821a500eafe7147af1d104381b84 289 Gene3D G3DSA:1.10.10.10 13 89 1.6E-13 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c06580 c06b821a500eafe7147af1d104381b84 289 SUPERFAMILY SSF46785 23 89 5.62E-14 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c45770 ab6a61b08d5465e7031b7a28c9eefbba 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 160 179 8.4E-7 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c45770 ab6a61b08d5465e7031b7a28c9eefbba 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 76 87 8.4E-7 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c45770 ab6a61b08d5465e7031b7a28c9eefbba 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 140 148 8.4E-7 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c45770 ab6a61b08d5465e7031b7a28c9eefbba 254 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 147 175 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 VAPA_1c45770 ab6a61b08d5465e7031b7a28c9eefbba 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 181 198 1.8E-25 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c45770 ab6a61b08d5465e7031b7a28c9eefbba 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 134 150 1.8E-25 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c45770 ab6a61b08d5465e7031b7a28c9eefbba 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 1.8E-25 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c45770 ab6a61b08d5465e7031b7a28c9eefbba 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 215 235 1.8E-25 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c45770 ab6a61b08d5465e7031b7a28c9eefbba 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 76 87 1.8E-25 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c45770 ab6a61b08d5465e7031b7a28c9eefbba 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 160 179 1.8E-25 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c45770 ab6a61b08d5465e7031b7a28c9eefbba 254 Gene3D G3DSA:3.40.50.720 1 253 1.3E-68 T 12-10-2018 VAPA_1c45770 ab6a61b08d5465e7031b7a28c9eefbba 254 Pfam PF00106 short chain dehydrogenase 7 203 1.7E-43 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c45770 ab6a61b08d5465e7031b7a28c9eefbba 254 SUPERFAMILY SSF51735 3 250 1.24E-57 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c43310 49e1b7017bd1dd260527093f05c28a6b 165 Pfam PF03748 Flagellar basal body-associated protein FliL 65 165 8.6E-21 T 12-10-2018 IPR005503 Flagellar basal body-associated protein FliL GO:0006935|GO:0009425|GO:0071973 VAPA_1c54250 cf398f70761139f7b6f453c0bd98787d 222 SUPERFAMILY SSF46785 10 82 2.18E-14 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c54250 cf398f70761139f7b6f453c0bd98787d 222 Pfam PF07729 FCD domain 88 206 5.9E-14 T 12-10-2018 IPR011711 GntR, C-terminal VAPA_1c54250 cf398f70761139f7b6f453c0bd98787d 222 Pfam PF00392 Bacterial regulatory proteins, gntR family 20 78 1.3E-12 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_1c54250 cf398f70761139f7b6f453c0bd98787d 222 SMART SM00345 20 78 1.3E-10 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_1c54250 cf398f70761139f7b6f453c0bd98787d 222 SMART SM00895 88 211 3.2E-7 T 12-10-2018 IPR011711 GntR, C-terminal VAPA_1c54250 cf398f70761139f7b6f453c0bd98787d 222 Gene3D G3DSA:1.10.10.10 2 79 7.8E-16 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c54250 cf398f70761139f7b6f453c0bd98787d 222 Gene3D G3DSA:1.20.120.530 84 213 5.9E-14 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal VAPA_1c54250 cf398f70761139f7b6f453c0bd98787d 222 SUPERFAMILY SSF48008 85 211 4.97E-13 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal VAPA_1c01780 e3a40ca35f11a15c4e69858f7ed21bf6 326 Pfam PF03466 LysR substrate binding domain 102 311 6.5E-24 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_1c01780 e3a40ca35f11a15c4e69858f7ed21bf6 326 Gene3D G3DSA:1.10.10.10 1 89 1.8E-30 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c01780 e3a40ca35f11a15c4e69858f7ed21bf6 326 Gene3D G3DSA:3.40.190.10 184 282 7.1E-59 T 12-10-2018 VAPA_1c01780 e3a40ca35f11a15c4e69858f7ed21bf6 326 SUPERFAMILY SSF46785 5 86 7.54E-21 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c01780 e3a40ca35f11a15c4e69858f7ed21bf6 326 Gene3D G3DSA:3.40.190.10 95 305 7.1E-59 T 12-10-2018 VAPA_1c01780 e3a40ca35f11a15c4e69858f7ed21bf6 326 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 25 36 8.0E-9 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c01780 e3a40ca35f11a15c4e69858f7ed21bf6 326 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 46 57 8.0E-9 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c01780 e3a40ca35f11a15c4e69858f7ed21bf6 326 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 36 46 8.0E-9 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c01780 e3a40ca35f11a15c4e69858f7ed21bf6 326 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 10 68 4.2E-18 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c01780 e3a40ca35f11a15c4e69858f7ed21bf6 326 SUPERFAMILY SSF53850 91 308 1.06E-40 T 12-10-2018 VAPA_2c09190 175916724aa89a131525317d560290a9 229 Pfam PF13417 Glutathione S-transferase, N-terminal domain 6 81 2.5E-11 T 12-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 VAPA_2c09190 175916724aa89a131525317d560290a9 229 Gene3D G3DSA:1.20.1050.10 85 196 7.1E-42 T 12-10-2018 VAPA_2c09190 175916724aa89a131525317d560290a9 229 SUPERFAMILY SSF52833 4 106 6.47E-18 T 12-10-2018 IPR036249 Thioredoxin-like superfamily VAPA_2c09190 175916724aa89a131525317d560290a9 229 Gene3D G3DSA:3.40.30.10 6 199 7.1E-42 T 12-10-2018 VAPA_2c09190 175916724aa89a131525317d560290a9 229 Pfam PF13410 Glutathione S-transferase, C-terminal domain 129 192 1.3E-8 T 12-10-2018 VAPA_2c09190 175916724aa89a131525317d560290a9 229 SUPERFAMILY SSF47616 73 214 8.49E-23 T 12-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily VAPA_1c45250 94e1d8ce7529817afdc12e5b39d7f05d 495 SUPERFAMILY SSF53850 27 494 3.62E-117 T 12-10-2018 VAPA_1c45250 94e1d8ce7529817afdc12e5b39d7f05d 495 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 74 401 5.2E-82 T 12-10-2018 IPR000914 Solute-binding protein family 5 domain VAPA_1c45250 94e1d8ce7529817afdc12e5b39d7f05d 495 Gene3D G3DSA:3.90.76.10 40 183 8.0E-107 T 12-10-2018 VAPA_1c45250 94e1d8ce7529817afdc12e5b39d7f05d 495 Gene3D G3DSA:3.40.190.10 184 478 8.0E-107 T 12-10-2018 VAPA_1c45250 94e1d8ce7529817afdc12e5b39d7f05d 495 PIRSF PIRSF002741 3 494 1.2E-95 T 12-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 VAPA_1c45250 94e1d8ce7529817afdc12e5b39d7f05d 495 Gene3D G3DSA:3.10.105.10 259 468 8.0E-107 T 12-10-2018 VAPA_1c16420 c01afb9a50e9b518b863c0dbf09ca76a 245 Gene3D G3DSA:3.40.50.1860 119 230 4.9E-56 T 12-10-2018 VAPA_1c16420 c01afb9a50e9b518b863c0dbf09ca76a 245 Gene3D G3DSA:3.40.50.1860 7 236 4.9E-56 T 12-10-2018 VAPA_1c16420 c01afb9a50e9b518b863c0dbf09ca76a 245 ProSitePatterns PS00923 Aspartate and glutamate racemases signature 1. 92 100 - T 12-10-2018 IPR018187 Asp/Glu racemase, active site 1 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 VAPA_1c16420 c01afb9a50e9b518b863c0dbf09ca76a 245 SUPERFAMILY SSF53681 6 129 2.88E-21 T 12-10-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 VAPA_1c16420 c01afb9a50e9b518b863c0dbf09ca76a 245 SUPERFAMILY SSF53681 120 216 1.02E-16 T 12-10-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 VAPA_1c16420 c01afb9a50e9b518b863c0dbf09ca76a 245 TIGRFAM TIGR00035 asp_race: aspartate racemase 5 240 6.9E-39 T 12-10-2018 IPR004380 Aspartate racemase GO:0006520|GO:0016855 VAPA_1c16420 c01afb9a50e9b518b863c0dbf09ca76a 245 Pfam PF01177 Asp/Glu/Hydantoin racemase 10 238 5.5E-47 T 12-10-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 VAPA_1c48150 b1275256229390d7cacc9143aaedfdc3 423 SUPERFAMILY SSF56281 19 416 1.4E-61 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like VAPA_1c48150 b1275256229390d7cacc9143aaedfdc3 423 Gene3D G3DSA:1.25.40.880 275 416 1.6E-25 T 12-10-2018 IPR038536 Alkyl/aryl-sulfatase, dimerisation domain superfamily VAPA_1c48150 b1275256229390d7cacc9143aaedfdc3 423 Gene3D G3DSA:3.60.15.30 15 272 7.4E-24 T 12-10-2018 VAPA_1c48150 b1275256229390d7cacc9143aaedfdc3 423 Pfam PF14863 Alkyl sulfatase dimerisation 276 414 8.8E-30 T 12-10-2018 IPR029228 Alkyl sulfatase dimerisation domain GO:0046983 VAPA_1c48150 b1275256229390d7cacc9143aaedfdc3 423 Pfam PF00753 Metallo-beta-lactamase superfamily 35 232 4.5E-5 T 12-10-2018 IPR001279 Metallo-beta-lactamase VAPA_1c03250 5e6ef014b5356c515d290f24bde8c050 333 Gene3D G3DSA:3.40.190.10 126 218 1.9E-15 T 12-10-2018 VAPA_1c03250 5e6ef014b5356c515d290f24bde8c050 333 Gene3D G3DSA:3.40.190.10 226 333 8.8E-7 T 12-10-2018 VAPA_1c03250 5e6ef014b5356c515d290f24bde8c050 333 Pfam PF09084 NMT1/THI5 like 52 270 1.8E-19 T 12-10-2018 IPR015168 SsuA/THI5-like VAPA_1c03250 5e6ef014b5356c515d290f24bde8c050 333 SUPERFAMILY SSF53850 39 271 2.4E-32 T 12-10-2018 VAPA_1c03250 5e6ef014b5356c515d290f24bde8c050 333 Gene3D G3DSA:3.40.190.10 36 121 2.1E-9 T 12-10-2018 VAPA_1c37850 08a2f343897d5f31b5975c61d7d91459 255 SMART SM00345 8 66 2.3E-11 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_1c37850 08a2f343897d5f31b5975c61d7d91459 255 Pfam PF00392 Bacterial regulatory proteins, gntR family 6 66 1.9E-15 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_1c37850 08a2f343897d5f31b5975c61d7d91459 255 Gene3D G3DSA:1.10.10.10 2 66 1.7E-16 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c37850 08a2f343897d5f31b5975c61d7d91459 255 SUPERFAMILY SSF46785 6 82 8.35E-16 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c37850 08a2f343897d5f31b5975c61d7d91459 255 SUPERFAMILY SSF48008 72 203 9.68E-25 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal VAPA_1c37850 08a2f343897d5f31b5975c61d7d91459 255 Gene3D G3DSA:1.20.120.530 69 208 3.9E-23 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal VAPA_1c37850 08a2f343897d5f31b5975c61d7d91459 255 SMART SM00895 76 198 4.0E-14 T 12-10-2018 IPR011711 GntR, C-terminal VAPA_1c37850 08a2f343897d5f31b5975c61d7d91459 255 Pfam PF07729 FCD domain 76 196 3.4E-20 T 12-10-2018 IPR011711 GntR, C-terminal VAPA_1c07020 f07d423e10a6db0164631277bca427f8 107 SUPERFAMILY SSF50022 7 106 6.94E-31 T 12-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 VAPA_1c07020 f07d423e10a6db0164631277bca427f8 107 Gene3D G3DSA:2.102.10.10 5 107 5.6E-34 T 12-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 VAPA_1c07020 f07d423e10a6db0164631277bca427f8 107 Pfam PF00355 Rieske [2Fe-2S] domain 7 94 3.8E-19 T 12-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 VAPA_1c08700 f5ca21977e27829e63794fea99a08450 232 Gene3D G3DSA:1.10.357.10 61 206 2.1E-31 T 12-10-2018 VAPA_1c08700 f5ca21977e27829e63794fea99a08450 232 SUPERFAMILY SSF46689 12 90 6.67E-14 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 VAPA_1c08700 f5ca21977e27829e63794fea99a08450 232 Gene3D G3DSA:1.10.10.60 9 60 7.1E-19 T 12-10-2018 VAPA_1c08700 f5ca21977e27829e63794fea99a08450 232 SUPERFAMILY SSF48498 90 196 1.3E-22 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily VAPA_1c08700 f5ca21977e27829e63794fea99a08450 232 Pfam PF00440 Bacterial regulatory proteins, tetR family 24 66 8.7E-9 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 VAPA_2c09390 09e439b1d56d7558584f36508c249181 391 Gene3D G3DSA:2.40.420.20 303 371 1.2E-85 T 12-10-2018 VAPA_2c09390 09e439b1d56d7558584f36508c249181 391 Gene3D G3DSA:1.10.287.470 102 175 1.2E-85 T 12-10-2018 VAPA_2c09390 09e439b1d56d7558584f36508c249181 391 Gene3D G3DSA:2.40.30.170 56 302 1.2E-85 T 12-10-2018 VAPA_2c09390 09e439b1d56d7558584f36508c249181 391 Pfam PF13533 Biotin-lipoyl like 69 116 2.5E-12 T 12-10-2018 IPR039562 Membrane fusion protein, biotin-lipoyl like domain VAPA_2c09390 09e439b1d56d7558584f36508c249181 391 Pfam PF13437 HlyD family secretion protein 179 283 6.6E-9 T 12-10-2018 VAPA_2c09390 09e439b1d56d7558584f36508c249181 391 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 50 373 3.9E-74 T 12-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 VAPA_2c09390 09e439b1d56d7558584f36508c249181 391 Gene3D G3DSA:2.40.50.100 67 212 1.2E-85 T 12-10-2018 VAPA_2c09390 09e439b1d56d7558584f36508c249181 391 SUPERFAMILY SSF111369 57 299 3.79E-52 T 12-10-2018 VAPA_2c05270 269583df7c021a292e9ed0f8d0027286 259 Pfam PF01564 Spermine/spermidine synthase domain 46 169 1.5E-6 T 12-10-2018 VAPA_2c05270 269583df7c021a292e9ed0f8d0027286 259 Gene3D G3DSA:3.40.50.150 20 234 3.4E-41 T 12-10-2018 VAPA_2c05270 269583df7c021a292e9ed0f8d0027286 259 SUPERFAMILY SSF53335 30 226 3.42E-39 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase VAPA_2c06210 db366f9714bad8653de47df8bd72e84d 219 Pfam PF00813 FliP family 14 214 3.6E-66 T 12-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 VAPA_2c06210 db366f9714bad8653de47df8bd72e84d 219 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 192 217 1.4E-63 T 12-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 VAPA_2c06210 db366f9714bad8653de47df8bd72e84d 219 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 51 70 1.4E-63 T 12-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 VAPA_2c06210 db366f9714bad8653de47df8bd72e84d 219 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 12 31 1.4E-63 T 12-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 VAPA_2c06210 db366f9714bad8653de47df8bd72e84d 219 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 31 51 1.4E-63 T 12-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 VAPA_2c06210 db366f9714bad8653de47df8bd72e84d 219 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 147 167 1.4E-63 T 12-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 VAPA_2c06210 db366f9714bad8653de47df8bd72e84d 219 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 168 189 1.4E-63 T 12-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 VAPA_2c06210 db366f9714bad8653de47df8bd72e84d 219 ProSitePatterns PS01061 Flagella transport protein fliP family signature 2. 195 207 - T 12-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 VAPA_2c06210 db366f9714bad8653de47df8bd72e84d 219 ProSitePatterns PS01060 Flagella transport protein fliP family signature 1. 147 162 - T 12-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 VAPA_2c06210 db366f9714bad8653de47df8bd72e84d 219 TIGRFAM TIGR01102 yscR: type III secretion apparatus protein, YscR/HrcR family 11 214 4.6E-80 T 12-10-2018 IPR005773 Yop virulence translocation protein R GO:0015031|GO:0016021 VAPA_1c14000 52a1fd7aeaaeeedf2b578cde3d5c3881 332 Gene3D G3DSA:3.40.190.150 36 321 1.3E-85 T 12-10-2018 VAPA_1c14000 52a1fd7aeaaeeedf2b578cde3d5c3881 332 PIRSF PIRSF017082 1 326 1.0E-57 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c14000 52a1fd7aeaaeeedf2b578cde3d5c3881 332 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 55 324 8.5E-62 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c14000 52a1fd7aeaaeeedf2b578cde3d5c3881 332 Gene3D G3DSA:3.40.190.10 133 257 1.3E-85 T 12-10-2018 VAPA_2c01420 de27a18ae835f6e0544d9098e3504336 360 SUPERFAMILY SSF53659 2 359 3.07E-106 T 12-10-2018 VAPA_2c01420 de27a18ae835f6e0544d9098e3504336 360 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 6 355 1.0E-87 T 12-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 VAPA_2c01420 de27a18ae835f6e0544d9098e3504336 360 SMART SM01329 5 355 2.5E-147 T 12-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 VAPA_2c01420 de27a18ae835f6e0544d9098e3504336 360 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 244 263 - T 12-10-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 VAPA_2c01420 de27a18ae835f6e0544d9098e3504336 360 Gene3D G3DSA:3.40.718.10 1 360 6.6E-122 T 12-10-2018 VAPA_1c54810 e7d0c10226b75805b9fc5de3dbed48f7 136 SUPERFAMILY SSF53933 41 135 1.02E-32 T 12-10-2018 IPR016191 Ribonuclease/ribotoxin GO:0003723|GO:0004540 VAPA_1c54810 e7d0c10226b75805b9fc5de3dbed48f7 136 Pfam PF00545 ribonuclease 49 132 2.7E-27 T 12-10-2018 IPR000026 Guanine-specific ribonuclease N1/T1/U2 GO:0003723|GO:0004521 VAPA_1c54810 e7d0c10226b75805b9fc5de3dbed48f7 136 Gene3D G3DSA:3.10.450.30 38 136 1.1E-34 T 12-10-2018 VAPA_2c08520 6d95fbff29797e890cd531866ce8262f 335 SUPERFAMILY SSF52283 1 136 2.55E-23 T 12-10-2018 VAPA_2c08520 6d95fbff29797e890cd531866ce8262f 335 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 21 309 3.1E-16 T 12-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 VAPA_2c08520 6d95fbff29797e890cd531866ce8262f 335 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 111 285 3.8E-49 T 12-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 VAPA_2c08520 6d95fbff29797e890cd531866ce8262f 335 SUPERFAMILY SSF51735 104 285 2.25E-48 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_2c08520 6d95fbff29797e890cd531866ce8262f 335 Gene3D G3DSA:3.40.50.720 2 309 6.0E-111 T 12-10-2018 VAPA_2c08520 6d95fbff29797e890cd531866ce8262f 335 Gene3D G3DSA:3.40.50.720 104 301 6.0E-111 T 12-10-2018 VAPA_1c18680 d2b0bd220f520a39a3d0ce310aefcd29 653 SMART SM00278 632 651 220.0 T 12-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 VAPA_1c18680 d2b0bd220f520a39a3d0ce310aefcd29 653 SMART SM00278 600 619 0.6 T 12-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 VAPA_1c18680 d2b0bd220f520a39a3d0ce310aefcd29 653 Gene3D G3DSA:4.10.860.10 204 241 1.2E-7 T 12-10-2018 VAPA_1c18680 d2b0bd220f520a39a3d0ce310aefcd29 653 Gene3D G3DSA:1.10.150.20 599 653 2.8E-22 T 12-10-2018 VAPA_1c18680 d2b0bd220f520a39a3d0ce310aefcd29 653 SUPERFAMILY SSF47781 561 653 1.18E-18 T 12-10-2018 IPR010994 RuvA domain 2-like VAPA_1c18680 d2b0bd220f520a39a3d0ce310aefcd29 653 SMART SM00465 19 100 8.2E-17 T 12-10-2018 IPR000305 GIY-YIG endonuclease VAPA_1c18680 d2b0bd220f520a39a3d0ce310aefcd29 653 Pfam PF08459 UvrC Helix-hairpin-helix N-terminal 415 585 1.8E-43 T 12-10-2018 IPR001162 UvrC family homology region VAPA_1c18680 d2b0bd220f520a39a3d0ce310aefcd29 653 Pfam PF01541 GIY-YIG catalytic domain 21 95 8.7E-11 T 12-10-2018 IPR000305 GIY-YIG endonuclease VAPA_1c18680 d2b0bd220f520a39a3d0ce310aefcd29 653 Pfam PF02151 UvrB/uvrC motif 207 238 2.9E-8 T 12-10-2018 IPR001943 UVR domain GO:0005515 VAPA_1c18680 d2b0bd220f520a39a3d0ce310aefcd29 653 TIGRFAM TIGR00194 uvrC: excinuclease ABC subunit C 10 476 2.2E-127 T 12-10-2018 IPR004791 UvrABC system, subunit C GO:0006289|GO:0009380|GO:0009381 VAPA_1c18680 d2b0bd220f520a39a3d0ce310aefcd29 653 SUPERFAMILY SSF82771 19 102 1.44E-21 T 12-10-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 VAPA_1c18680 d2b0bd220f520a39a3d0ce310aefcd29 653 Gene3D G3DSA:3.40.1440.10 6 104 1.9E-31 T 12-10-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 VAPA_1c18680 d2b0bd220f520a39a3d0ce310aefcd29 653 SUPERFAMILY SSF46600 192 244 4.18E-11 T 12-10-2018 IPR036876 UVR domain superfamily VAPA_1c18680 d2b0bd220f520a39a3d0ce310aefcd29 653 Hamap MF_00203 UvrABC system protein C [uvrC]. 6 651 26.661 T 12-10-2018 IPR004791 UvrABC system, subunit C GO:0006289|GO:0009380|GO:0009381 VAPA_1c18680 d2b0bd220f520a39a3d0ce310aefcd29 653 Pfam PF14520 Helix-hairpin-helix domain 601 652 3.1E-6 T 12-10-2018 VAPA_1c08020 23b26953a68b5c83a2a85b9e88ecf25e 230 SUPERFAMILY SSF54593 4 115 2.36E-6 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase VAPA_1c08020 23b26953a68b5c83a2a85b9e88ecf25e 230 Gene3D G3DSA:3.10.180.10 3 168 1.8E-8 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase VAPA_1c08020 23b26953a68b5c83a2a85b9e88ecf25e 230 Pfam PF13468 Glyoxalase-like domain 5 197 1.1E-33 T 12-10-2018 IPR025870 Glyoxalase-like domain VAPA_2c04210 7ba4d3ee349f77a32c3d6d3512187ee3 157 Pfam PF01527 Transposase 52 125 1.0E-6 T 12-10-2018 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 VAPA_1c31520 7ba4d3ee349f77a32c3d6d3512187ee3 157 Pfam PF01527 Transposase 52 125 1.0E-6 T 12-10-2018 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 VAPA_2c11400 dab69e80ebce42aef5ebfe82cd577436 239 Pfam PF00005 ABC transporter 22 165 1.6E-27 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_2c11400 dab69e80ebce42aef5ebfe82cd577436 239 SUPERFAMILY SSF52540 4 235 3.97E-58 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_2c11400 dab69e80ebce42aef5ebfe82cd577436 239 Gene3D G3DSA:3.40.50.300 1 234 2.2E-55 T 12-10-2018 VAPA_2c05780 e3f0d448627f783485e1aaf0fdc8f88e 736 SMART SM01008 32 138 1.2E-27 T 12-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead VAPA_2c05780 e3f0d448627f783485e1aaf0fdc8f88e 736 Gene3D G3DSA:3.30.365.10 167 387 1.7E-60 T 12-10-2018 VAPA_2c05780 e3f0d448627f783485e1aaf0fdc8f88e 736 SUPERFAMILY SSF56003 149 732 3.01E-167 T 12-10-2018 IPR037165 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain superfamily GO:0016491|GO:0055114 VAPA_2c05780 e3f0d448627f783485e1aaf0fdc8f88e 736 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 34 136 1.2E-20 T 12-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead VAPA_2c05780 e3f0d448627f783485e1aaf0fdc8f88e 736 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 164 672 2.9E-126 T 12-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 VAPA_2c05780 e3f0d448627f783485e1aaf0fdc8f88e 736 Gene3D G3DSA:3.30.365.20 405 733 1.4E-84 T 12-10-2018 VAPA_2c05780 e3f0d448627f783485e1aaf0fdc8f88e 736 SUPERFAMILY SSF54665 6 138 2.75E-31 T 12-10-2018 IPR036856 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead superfamily VAPA_2c05780 e3f0d448627f783485e1aaf0fdc8f88e 736 Gene3D G3DSA:3.90.1170.50 3 138 1.8E-23 T 12-10-2018 VAPA_2c05780 e3f0d448627f783485e1aaf0fdc8f88e 736 Gene3D G3DSA:3.30.365.10 191 283 1.7E-60 T 12-10-2018 VAPA_1c37050 c17e23a74b5bf1ac063f60986a578cd5 325 Pfam PF01544 CorA-like Mg2+ transporter protein 31 321 1.1E-57 T 12-10-2018 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 VAPA_1c37050 c17e23a74b5bf1ac063f60986a578cd5 325 SUPERFAMILY SSF143865 2 257 7.06E-68 T 12-10-2018 VAPA_1c37050 c17e23a74b5bf1ac063f60986a578cd5 325 Gene3D G3DSA:1.20.58.340 249 325 2.9E-21 T 12-10-2018 VAPA_1c37050 c17e23a74b5bf1ac063f60986a578cd5 325 Gene3D G3DSA:1.20.58.340 134 246 2.8E-30 T 12-10-2018 VAPA_1c37050 c17e23a74b5bf1ac063f60986a578cd5 325 SUPERFAMILY SSF144083 262 322 1.83E-16 T 12-10-2018 VAPA_1c37050 c17e23a74b5bf1ac063f60986a578cd5 325 Gene3D G3DSA:3.30.460.20 1 133 5.1E-29 T 12-10-2018 VAPA_2c03590 bde84fd7aecd2ff8bbdeb27e92b15237 294 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 156 175 8.8E-6 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c03590 bde84fd7aecd2ff8bbdeb27e92b15237 294 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 8.8E-6 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c03590 bde84fd7aecd2ff8bbdeb27e92b15237 294 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 136 144 8.8E-6 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c03590 bde84fd7aecd2ff8bbdeb27e92b15237 294 Gene3D G3DSA:3.40.50.720 2 260 1.7E-52 T 12-10-2018 VAPA_2c03590 bde84fd7aecd2ff8bbdeb27e92b15237 294 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 6 188 0.0017 T 12-10-2018 VAPA_2c03590 bde84fd7aecd2ff8bbdeb27e92b15237 294 Pfam PF00106 short chain dehydrogenase 8 200 8.9E-41 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c03590 bde84fd7aecd2ff8bbdeb27e92b15237 294 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 3.9E-15 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c03590 bde84fd7aecd2ff8bbdeb27e92b15237 294 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 3.9E-15 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c03590 bde84fd7aecd2ff8bbdeb27e92b15237 294 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 3.9E-15 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c03590 bde84fd7aecd2ff8bbdeb27e92b15237 294 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 3.9E-15 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c03590 bde84fd7aecd2ff8bbdeb27e92b15237 294 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 3.9E-15 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c03590 bde84fd7aecd2ff8bbdeb27e92b15237 294 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 143 171 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 VAPA_2c03590 bde84fd7aecd2ff8bbdeb27e92b15237 294 SUPERFAMILY SSF51735 6 255 4.4E-54 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c21770 915955201b43fdbbe3acc572d211cec8 661 SUPERFAMILY SSF55785 208 314 3.05E-8 T 12-10-2018 IPR035965 PAS domain superfamily VAPA_1c21770 915955201b43fdbbe3acc572d211cec8 661 SMART SM00382 364 512 8.2E-10 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c21770 915955201b43fdbbe3acc572d211cec8 661 Pfam PF00158 Sigma-54 interaction domain 346 511 8.3E-66 T 12-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 VAPA_1c21770 915955201b43fdbbe3acc572d211cec8 661 Gene3D G3DSA:3.30.450.20 206 316 2.1E-15 T 12-10-2018 VAPA_1c21770 915955201b43fdbbe3acc572d211cec8 661 SUPERFAMILY SSF159800 27 208 1.31E-43 T 12-10-2018 VAPA_1c21770 915955201b43fdbbe3acc572d211cec8 661 Gene3D G3DSA:3.40.50.2300 33 204 4.2E-58 T 12-10-2018 VAPA_1c21770 915955201b43fdbbe3acc572d211cec8 661 Gene3D G3DSA:1.10.8.60 516 591 1.6E-12 T 12-10-2018 VAPA_1c21770 915955201b43fdbbe3acc572d211cec8 661 TIGRFAM TIGR02329 propionate_PrpR: propionate catabolism operon regulatory protein PrpR 27 655 7.2E-173 T 12-10-2018 IPR012704 Signal transduction response regulator, propionate catabolism, transcriptional regulator PrpR GO:0000156|GO:0000160|GO:0003677|GO:0005737|GO:0019629 VAPA_1c21770 915955201b43fdbbe3acc572d211cec8 661 SUPERFAMILY SSF46689 561 656 4.35E-10 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 VAPA_1c21770 915955201b43fdbbe3acc572d211cec8 661 Gene3D G3DSA:3.40.50.300 330 515 9.4E-63 T 12-10-2018 VAPA_1c21770 915955201b43fdbbe3acc572d211cec8 661 Pfam PF02954 Bacterial regulatory protein, Fis family 620 656 3.3E-9 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 VAPA_1c21770 915955201b43fdbbe3acc572d211cec8 661 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 561 570 - T 12-10-2018 IPR025944 Sigma-54 interaction domain, conserved site VAPA_1c21770 915955201b43fdbbe3acc572d211cec8 661 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 431 446 - T 12-10-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 VAPA_1c21770 915955201b43fdbbe3acc572d211cec8 661 SUPERFAMILY SSF52540 346 578 6.58E-59 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c21770 915955201b43fdbbe3acc572d211cec8 661 SMART SM00091 217 283 0.0012 T 12-10-2018 IPR000014 PAS domain VAPA_1c21770 915955201b43fdbbe3acc572d211cec8 661 Pfam PF06506 Propionate catabolism activator 49 211 3.5E-46 T 12-10-2018 IPR010524 Signal transduction response regulator, propionate catabolism activator, N-terminal GO:0000156|GO:0000160|GO:0003677|GO:0005524 VAPA_1c21770 915955201b43fdbbe3acc572d211cec8 661 Gene3D G3DSA:3.40.50.10660 102 189 4.2E-58 T 12-10-2018 VAPA_1c21770 915955201b43fdbbe3acc572d211cec8 661 Gene3D G3DSA:1.10.10.60 619 656 1.9E-9 T 12-10-2018 VAPA_1c21770 915955201b43fdbbe3acc572d211cec8 661 Pfam PF00989 PAS fold 221 315 1.6E-5 T 12-10-2018 IPR013767 PAS fold GO:0006355 VAPA_1c21770 915955201b43fdbbe3acc572d211cec8 661 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 368 381 - T 12-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 VAPA_2c12350 b3be083bdec1bddf0bbc3c35e6c43c92 391 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 60 76 1.2E-10 T 12-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 VAPA_2c12350 b3be083bdec1bddf0bbc3c35e6c43c92 391 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 38 54 1.2E-10 T 12-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 VAPA_2c12350 b3be083bdec1bddf0bbc3c35e6c43c92 391 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 265 283 1.2E-10 T 12-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 VAPA_2c12350 b3be083bdec1bddf0bbc3c35e6c43c92 391 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 79 97 1.2E-10 T 12-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 VAPA_2c12350 b3be083bdec1bddf0bbc3c35e6c43c92 391 Gene3D G3DSA:3.40.50.2300 160 385 2.7E-100 T 12-10-2018 VAPA_2c12350 b3be083bdec1bddf0bbc3c35e6c43c92 391 Pfam PF13458 Periplasmic binding protein 37 385 1.8E-58 T 12-10-2018 IPR028081 Leucine-binding protein domain VAPA_2c12350 b3be083bdec1bddf0bbc3c35e6c43c92 391 SUPERFAMILY SSF53822 36 390 1.55E-79 T 12-10-2018 IPR028082 Periplasmic binding protein-like I VAPA_2c12350 b3be083bdec1bddf0bbc3c35e6c43c92 391 Gene3D G3DSA:3.40.50.2300 40 373 2.7E-100 T 12-10-2018 VAPA_1c32840 e5e5c66d59bad8e454461b1248c89304 1667 SUPERFAMILY SSF56801 440 1005 2.75E-147 T 12-10-2018 VAPA_1c32840 e5e5c66d59bad8e454461b1248c89304 1667 SUPERFAMILY SSF52777 1268 1515 4.67E-47 T 12-10-2018 VAPA_1c32840 e5e5c66d59bad8e454461b1248c89304 1667 SUPERFAMILY SSF52777 200 449 2.89E-46 T 12-10-2018 VAPA_1c32840 e5e5c66d59bad8e454461b1248c89304 1667 Pfam PF13193 AMP-binding enzyme C-terminal domain 890 965 3.8E-9 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain VAPA_1c32840 e5e5c66d59bad8e454461b1248c89304 1667 Gene3D G3DSA:3.30.559.30 1272 1516 1.5E-47 T 12-10-2018 VAPA_1c32840 e5e5c66d59bad8e454461b1248c89304 1667 Gene3D G3DSA:3.30.300.30 878 984 4.0E-31 T 12-10-2018 VAPA_1c32840 e5e5c66d59bad8e454461b1248c89304 1667 Gene3D G3DSA:1.10.1200.10 1557 1635 2.4E-12 T 12-10-2018 IPR036736 ACP-like superfamily VAPA_1c32840 e5e5c66d59bad8e454461b1248c89304 1667 Gene3D G3DSA:3.40.50.12780 474 874 1.6E-124 T 12-10-2018 VAPA_1c32840 e5e5c66d59bad8e454461b1248c89304 1667 SUPERFAMILY SSF47336 1557 1612 1.96E-10 T 12-10-2018 IPR036736 ACP-like superfamily VAPA_1c32840 e5e5c66d59bad8e454461b1248c89304 1667 SUPERFAMILY SSF47336 988 1058 3.01E-15 T 12-10-2018 IPR036736 ACP-like superfamily VAPA_1c32840 e5e5c66d59bad8e454461b1248c89304 1667 SUPERFAMILY SSF52777 14 214 1.56E-34 T 12-10-2018 VAPA_1c32840 e5e5c66d59bad8e454461b1248c89304 1667 ProSitePatterns PS00455 Putative AMP-binding domain signature. 628 639 - T 12-10-2018 IPR020845 AMP-binding, conserved site VAPA_1c32840 e5e5c66d59bad8e454461b1248c89304 1667 Gene3D G3DSA:3.30.559.10 1078 1271 3.4E-50 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 VAPA_1c32840 e5e5c66d59bad8e454461b1248c89304 1667 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1586 1601 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site VAPA_1c32840 e5e5c66d59bad8e454461b1248c89304 1667 Pfam PF00668 Condensation domain 1079 1515 3.9E-79 T 12-10-2018 IPR001242 Condensation domain VAPA_1c32840 e5e5c66d59bad8e454461b1248c89304 1667 Pfam PF00668 Condensation domain 17 460 7.3E-80 T 12-10-2018 IPR001242 Condensation domain VAPA_1c32840 e5e5c66d59bad8e454461b1248c89304 1667 SMART SM00823 Phosphopantetheine attachment site 1560 1619 0.012 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 VAPA_1c32840 e5e5c66d59bad8e454461b1248c89304 1667 SMART SM00823 Phosphopantetheine attachment site 990 1062 2.0E-4 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 VAPA_1c32840 e5e5c66d59bad8e454461b1248c89304 1667 Gene3D G3DSA:1.10.1200.10 985 1063 3.3E-19 T 12-10-2018 IPR036736 ACP-like superfamily VAPA_1c32840 e5e5c66d59bad8e454461b1248c89304 1667 Pfam PF00501 AMP-binding enzyme 486 882 9.0E-96 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 VAPA_1c32840 e5e5c66d59bad8e454461b1248c89304 1667 Gene3D G3DSA:3.30.559.10 19 390 8.8E-100 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 VAPA_1c32840 e5e5c66d59bad8e454461b1248c89304 1667 SUPERFAMILY SSF52777 1083 1262 1.11E-39 T 12-10-2018 VAPA_1c32840 e5e5c66d59bad8e454461b1248c89304 1667 Pfam PF00550 Phosphopantetheine attachment site 994 1057 5.1E-11 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain VAPA_1c32840 e5e5c66d59bad8e454461b1248c89304 1667 Pfam PF00550 Phosphopantetheine attachment site 1562 1622 3.2E-10 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain VAPA_1c32840 e5e5c66d59bad8e454461b1248c89304 1667 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 501 906 1.6E-126 T 12-10-2018 IPR010071 Amino acid adenylation domain VAPA_1c32840 e5e5c66d59bad8e454461b1248c89304 1667 Gene3D G3DSA:3.30.559.30 198 445 8.8E-100 T 12-10-2018 VAPA_1c49160 b0bd36fe46bd77fa916cdccfe554eb48 267 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 79 253 2.7E-20 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 VAPA_1c49160 b0bd36fe46bd77fa916cdccfe554eb48 267 SUPERFAMILY SSF161098 60 244 3.01E-24 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c49160 b0bd36fe46bd77fa916cdccfe554eb48 267 Gene3D G3DSA:1.10.3720.10 57 255 4.6E-20 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c17440 30aa5dc12179a4cd485497a70a11e424 59 Pfam PF12244 Protein of unknown function (DUF3606) 8 57 6.7E-14 T 12-10-2018 IPR022037 Protein of unknown function DUF3606 VAPA_1c22380 351bbbe81f35aa8b2d3129cf2adfd117 321 Gene3D G3DSA:3.40.50.80 107 224 6.1E-25 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain VAPA_1c22380 351bbbe81f35aa8b2d3129cf2adfd117 321 Pfam PF00970 Oxidoreductase FAD-binding domain 11 107 2.1E-5 T 12-10-2018 IPR008333 Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain Reactome: R-HSA-1237044 VAPA_1c22380 351bbbe81f35aa8b2d3129cf2adfd117 321 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 243 312 3.2E-11 T 12-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 VAPA_1c22380 351bbbe81f35aa8b2d3129cf2adfd117 321 Gene3D G3DSA:2.40.30.10 2 106 3.9E-22 T 12-10-2018 VAPA_1c22380 351bbbe81f35aa8b2d3129cf2adfd117 321 SUPERFAMILY SSF54292 214 319 2.23E-27 T 12-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 VAPA_1c22380 351bbbe81f35aa8b2d3129cf2adfd117 321 Gene3D G3DSA:3.10.20.30 225 321 7.0E-24 T 12-10-2018 IPR012675 Beta-grasp domain superfamily VAPA_1c22380 351bbbe81f35aa8b2d3129cf2adfd117 321 PRINTS PR00409 Phthalate dioxygenase reductase family signature 32 42 1.1E-25 T 12-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 VAPA_1c22380 351bbbe81f35aa8b2d3129cf2adfd117 321 PRINTS PR00409 Phthalate dioxygenase reductase family signature 117 136 1.1E-25 T 12-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 VAPA_1c22380 351bbbe81f35aa8b2d3129cf2adfd117 321 PRINTS PR00409 Phthalate dioxygenase reductase family signature 95 109 1.1E-25 T 12-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 VAPA_1c22380 351bbbe81f35aa8b2d3129cf2adfd117 321 PRINTS PR00409 Phthalate dioxygenase reductase family signature 142 151 1.1E-25 T 12-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 VAPA_1c22380 351bbbe81f35aa8b2d3129cf2adfd117 321 PRINTS PR00409 Phthalate dioxygenase reductase family signature 42 54 1.1E-25 T 12-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 VAPA_1c22380 351bbbe81f35aa8b2d3129cf2adfd117 321 PRINTS PR00409 Phthalate dioxygenase reductase family signature 192 200 1.1E-25 T 12-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 VAPA_1c22380 351bbbe81f35aa8b2d3129cf2adfd117 321 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 270 278 - T 12-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 VAPA_1c22380 351bbbe81f35aa8b2d3129cf2adfd117 321 SUPERFAMILY SSF63380 4 105 2.15E-21 T 12-10-2018 IPR017938 Riboflavin synthase-like beta-barrel VAPA_1c22380 351bbbe81f35aa8b2d3129cf2adfd117 321 SUPERFAMILY SSF52343 103 227 1.44E-25 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain VAPA_1c08490 c323e154d7ed91fc2b58958dea96cf6c 244 Gene3D G3DSA:3.40.50.720 1 244 6.5E-73 T 12-10-2018 VAPA_1c08490 c323e154d7ed91fc2b58958dea96cf6c 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 206 226 8.7E-38 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c08490 c323e154d7ed91fc2b58958dea96cf6c 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 8.7E-38 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c08490 c323e154d7ed91fc2b58958dea96cf6c 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 119 135 8.7E-38 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c08490 c323e154d7ed91fc2b58958dea96cf6c 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 72 83 8.7E-38 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c08490 c323e154d7ed91fc2b58958dea96cf6c 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 146 165 8.7E-38 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c08490 c323e154d7ed91fc2b58958dea96cf6c 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 167 184 8.7E-38 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c08490 c323e154d7ed91fc2b58958dea96cf6c 244 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 133 161 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 VAPA_1c08490 c323e154d7ed91fc2b58958dea96cf6c 244 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 125 133 9.5E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c08490 c323e154d7ed91fc2b58958dea96cf6c 244 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 146 165 9.5E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c08490 c323e154d7ed91fc2b58958dea96cf6c 244 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 72 83 9.5E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c08490 c323e154d7ed91fc2b58958dea96cf6c 244 SUPERFAMILY SSF51735 4 244 8.89E-70 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c08490 c323e154d7ed91fc2b58958dea96cf6c 244 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 243 3.8E-57 T 12-10-2018 VAPA_1c48640 dab4945e8f2e1e18932ed8922dd3620f 306 Gene3D G3DSA:3.20.20.70 1 304 3.0E-130 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 VAPA_1c48640 dab4945e8f2e1e18932ed8922dd3620f 306 SUPERFAMILY SSF51569 1 298 5.49E-71 T 12-10-2018 VAPA_1c48640 dab4945e8f2e1e18932ed8922dd3620f 306 Pfam PF00682 HMGL-like 6 282 1.0E-55 T 12-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 VAPA_1c27640 ec21f262eb38c6990d127ef84c75de51 367 Pfam PF01904 Protein of unknown function DUF72 91 359 2.3E-40 T 12-10-2018 IPR002763 Protein of unknown function DUF72 VAPA_1c27640 ec21f262eb38c6990d127ef84c75de51 367 Gene3D G3DSA:3.20.20.410 63 363 4.6E-30 T 12-10-2018 IPR036520 UPF0759 superfamily VAPA_1c27640 ec21f262eb38c6990d127ef84c75de51 367 SUPERFAMILY SSF117396 70 359 2.88E-48 T 12-10-2018 IPR036520 UPF0759 superfamily VAPA_1c27250 891066ad2910134e82cbc18d71e5acff 76 SMART SM00749 8 71 6.5E-4 T 12-10-2018 IPR014004 Transport-associated and nodulation domain, bacteria VAPA_1c27250 891066ad2910134e82cbc18d71e5acff 76 Pfam PF04972 BON domain 4 70 1.8E-16 T 12-10-2018 IPR007055 BON domain VAPA_1c23600 e0b8cc5e1556341ac4fd427c90d98846 338 Gene3D G3DSA:3.10.290.10 32 97 2.6E-15 T 12-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 VAPA_1c23600 e0b8cc5e1556341ac4fd427c90d98846 338 Pfam PF00849 RNA pseudouridylate synthase 119 274 6.0E-26 T 12-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 VAPA_1c23600 e0b8cc5e1556341ac4fd427c90d98846 338 SUPERFAMILY SSF55120 104 335 3.29E-68 T 12-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 VAPA_1c23600 e0b8cc5e1556341ac4fd427c90d98846 338 Gene3D G3DSA:3.30.2350.10 111 332 2.3E-64 T 12-10-2018 VAPA_1c23600 e0b8cc5e1556341ac4fd427c90d98846 338 SUPERFAMILY SSF55174 42 143 2.52E-9 T 12-10-2018 VAPA_1c23600 e0b8cc5e1556341ac4fd427c90d98846 338 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 40 331 1.7E-78 T 12-10-2018 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 VAPA_1c23600 e0b8cc5e1556341ac4fd427c90d98846 338 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 161 175 - T 12-10-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 VAPA_2c09790 3bbc814806fd1b92993e41762f5859d1 387 Gene3D G3DSA:2.40.110.10 126 239 4.5E-28 T 12-10-2018 VAPA_2c09790 3bbc814806fd1b92993e41762f5859d1 387 SUPERFAMILY SSF56645 3 243 1.44E-58 T 12-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 VAPA_2c09790 3bbc814806fd1b92993e41762f5859d1 387 Gene3D G3DSA:1.20.140.10 240 386 3.5E-39 T 12-10-2018 VAPA_2c09790 3bbc814806fd1b92993e41762f5859d1 387 Gene3D G3DSA:1.10.540.10 1 125 1.1E-27 T 12-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 VAPA_2c09790 3bbc814806fd1b92993e41762f5859d1 387 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 232 381 4.8E-39 T 12-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 VAPA_2c09790 3bbc814806fd1b92993e41762f5859d1 387 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 10 123 1.2E-17 T 12-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 VAPA_2c09790 3bbc814806fd1b92993e41762f5859d1 387 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 127 220 5.4E-17 T 12-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 VAPA_2c09790 3bbc814806fd1b92993e41762f5859d1 387 SUPERFAMILY SSF47203 230 383 8.86E-45 T 12-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 VAPA_1c12040 273e9c7dcc7da03e1d6741d6b4a3184c 182 Gene3D G3DSA:3.40.50.300 2 169 2.1E-52 T 12-10-2018 VAPA_1c12040 273e9c7dcc7da03e1d6741d6b4a3184c 182 Pfam PF01202 Shikimate kinase 9 165 1.9E-46 T 12-10-2018 IPR031322 Shikimate kinase/gluconokinase KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 VAPA_1c12040 273e9c7dcc7da03e1d6741d6b4a3184c 182 ProSitePatterns PS01128 Shikimate kinase signature. 56 81 - T 12-10-2018 IPR023000 Shikimate kinase, conserved site KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 VAPA_1c12040 273e9c7dcc7da03e1d6741d6b4a3184c 182 SUPERFAMILY SSF52540 3 162 1.51E-30 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c12040 273e9c7dcc7da03e1d6741d6b4a3184c 182 Hamap MF_00109 Shikimate kinase [aroK]. 1 166 26.514 T 12-10-2018 IPR000623 Shikimate kinase/Threonine synthase-like 1 KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 VAPA_1c12040 273e9c7dcc7da03e1d6741d6b4a3184c 182 PRINTS PR01100 Shikimate kinase family signature 73 82 1.1E-20 T 12-10-2018 VAPA_1c12040 273e9c7dcc7da03e1d6741d6b4a3184c 182 PRINTS PR01100 Shikimate kinase family signature 55 63 1.1E-20 T 12-10-2018 VAPA_1c12040 273e9c7dcc7da03e1d6741d6b4a3184c 182 PRINTS PR01100 Shikimate kinase family signature 27 40 1.1E-20 T 12-10-2018 VAPA_1c12040 273e9c7dcc7da03e1d6741d6b4a3184c 182 PRINTS PR01100 Shikimate kinase family signature 94 111 1.1E-20 T 12-10-2018 VAPA_1c12040 273e9c7dcc7da03e1d6741d6b4a3184c 182 PRINTS PR01100 Shikimate kinase family signature 3 18 1.1E-20 T 12-10-2018 VAPA_2c05400 d4960cf15d42adb69d12da8a710a3ef7 249 SUPERFAMILY SSF54862 37 133 4.54E-17 T 12-10-2018 VAPA_2c05400 d4960cf15d42adb69d12da8a710a3ef7 249 SUPERFAMILY SSF56770 118 246 4.58E-39 T 12-10-2018 VAPA_2c05400 d4960cf15d42adb69d12da8a710a3ef7 249 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 133 242 9.1E-22 T 12-10-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VAPA_2c05400 d4960cf15d42adb69d12da8a710a3ef7 249 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 66 77 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site VAPA_2c05400 d4960cf15d42adb69d12da8a710a3ef7 249 Gene3D G3DSA:3.30.70.20 35 113 1.1E-8 T 12-10-2018 VAPA_2c05400 d4960cf15d42adb69d12da8a710a3ef7 249 Pfam PF12838 4Fe-4S dicluster domain 40 79 1.5E-6 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain VAPA_2c05400 d4960cf15d42adb69d12da8a710a3ef7 249 Gene3D G3DSA:3.40.50.12280 114 247 1.7E-40 T 12-10-2018 VAPA_1c44610 d34b6eb9e5443cc4f264434e6a47cf8f 450 Pfam PF01343 Peptidase family S49 145 288 1.9E-32 T 12-10-2018 IPR002142 Peptidase S49 GO:0006508|GO:0008233 VAPA_1c44610 d34b6eb9e5443cc4f264434e6a47cf8f 450 Gene3D G3DSA:3.90.226.10 74 284 1.8E-38 T 12-10-2018 VAPA_1c44610 d34b6eb9e5443cc4f264434e6a47cf8f 450 Gene3D G3DSA:3.40.1750.20 182 248 1.8E-38 T 12-10-2018 VAPA_1c44610 d34b6eb9e5443cc4f264434e6a47cf8f 450 SUPERFAMILY SSF52096 67 278 1.99E-21 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily VAPA_2c07710 79bcc9c6bb80ed6b6fed95d2041186c6 1931 SUPERFAMILY SSF51126 65 332 2.7E-40 T 12-10-2018 IPR011050 Pectin lyase fold/virulence factor VAPA_2c07710 79bcc9c6bb80ed6b6fed95d2041186c6 1931 Gene3D G3DSA:2.160.20.10 50 370 2.2E-76 T 12-10-2018 IPR012334 Pectin lyase fold VAPA_2c07710 79bcc9c6bb80ed6b6fed95d2041186c6 1931 TIGRFAM TIGR01901 adhes_NPXG: filamentous hemagglutinin family N-terminal domain 82 156 9.1E-23 T 12-10-2018 IPR008638 Filamentous haemagglutinin, N-terminal VAPA_2c07710 79bcc9c6bb80ed6b6fed95d2041186c6 1931 SMART SM00912 48 160 5.1E-38 T 12-10-2018 IPR008638 Filamentous haemagglutinin, N-terminal VAPA_2c07710 79bcc9c6bb80ed6b6fed95d2041186c6 1931 Pfam PF05860 haemagglutination activity domain 66 160 2.6E-22 T 12-10-2018 IPR008638 Filamentous haemagglutinin, N-terminal VAPA_2c07710 79bcc9c6bb80ed6b6fed95d2041186c6 1931 Gene3D G3DSA:2.160.20.110 1052 1161 1.1E-18 T 12-10-2018 VAPA_2c07710 79bcc9c6bb80ed6b6fed95d2041186c6 1931 Gene3D G3DSA:2.160.20.110 844 1028 1.3E-31 T 12-10-2018 VAPA_2c07710 79bcc9c6bb80ed6b6fed95d2041186c6 1931 Gene3D G3DSA:2.160.20.110 486 661 1.8E-33 T 12-10-2018 VAPA_2c07710 79bcc9c6bb80ed6b6fed95d2041186c6 1931 Gene3D G3DSA:2.160.20.110 1162 1334 1.2E-13 T 12-10-2018 VAPA_2c07710 79bcc9c6bb80ed6b6fed95d2041186c6 1931 Pfam PF07581 The GLUG motif 957 983 4.7E-4 T 12-10-2018 IPR011493 GLUG VAPA_2c07710 79bcc9c6bb80ed6b6fed95d2041186c6 1931 Pfam PF07581 The GLUG motif 1044 1068 4.4E-4 T 12-10-2018 IPR011493 GLUG VAPA_2c07710 79bcc9c6bb80ed6b6fed95d2041186c6 1931 Pfam PF07581 The GLUG motif 593 617 0.002 T 12-10-2018 IPR011493 GLUG VAPA_2c07710 79bcc9c6bb80ed6b6fed95d2041186c6 1931 Pfam PF07581 The GLUG motif 1014 1041 0.0013 T 12-10-2018 IPR011493 GLUG VAPA_2c07710 79bcc9c6bb80ed6b6fed95d2041186c6 1931 Pfam PF07581 The GLUG motif 650 673 0.0013 T 12-10-2018 IPR011493 GLUG VAPA_2c05560 3e712e5d0ccaa04a19678ad576a6a006 287 Pfam PF13340 Putative transposase of IS4/5 family (DUF4096) 12 96 1.0E-25 T 12-10-2018 IPR025161 Putative transposase IS4/IS5 family VAPA_2c05560 3e712e5d0ccaa04a19678ad576a6a006 287 Pfam PF01609 Transposase DDE domain 116 272 2.0E-13 T 12-10-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 VAPA_2c04230 20472c103a654f49a8d4d7f900017362 169 Gene3D G3DSA:3.10.580.10 1 161 2.4E-33 T 12-10-2018 VAPA_2c04230 20472c103a654f49a8d4d7f900017362 169 SUPERFAMILY SSF54631 1 128 9.1E-29 T 12-10-2018 VAPA_2c04230 20472c103a654f49a8d4d7f900017362 169 SMART SM00116 10 60 8.8E-6 T 12-10-2018 IPR000644 CBS domain VAPA_2c04230 20472c103a654f49a8d4d7f900017362 169 SMART SM00116 78 126 4.9E-8 T 12-10-2018 IPR000644 CBS domain VAPA_2c04230 20472c103a654f49a8d4d7f900017362 169 Pfam PF00571 CBS domain 71 126 7.1E-12 T 12-10-2018 IPR000644 CBS domain VAPA_2c04230 20472c103a654f49a8d4d7f900017362 169 Pfam PF00571 CBS domain 4 56 1.2E-7 T 12-10-2018 IPR000644 CBS domain VAPA_1c55050 1b7b1f09f48061851265d76858b652a3 332 Pfam PF01380 SIS domain 52 180 1.0E-30 T 12-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 VAPA_1c55050 1b7b1f09f48061851265d76858b652a3 332 Gene3D G3DSA:3.10.580.10 204 329 3.0E-42 T 12-10-2018 VAPA_1c55050 1b7b1f09f48061851265d76858b652a3 332 Gene3D G3DSA:3.40.50.10490 11 203 6.3E-61 T 12-10-2018 VAPA_1c55050 1b7b1f09f48061851265d76858b652a3 332 SMART SM00116 218 266 6.8E-6 T 12-10-2018 IPR000644 CBS domain VAPA_1c55050 1b7b1f09f48061851265d76858b652a3 332 SMART SM00116 283 331 0.16 T 12-10-2018 IPR000644 CBS domain VAPA_1c55050 1b7b1f09f48061851265d76858b652a3 332 SUPERFAMILY SSF54631 270 329 2.3E-11 T 12-10-2018 VAPA_1c55050 1b7b1f09f48061851265d76858b652a3 332 SUPERFAMILY SSF53697 18 265 1.98E-61 T 12-10-2018 VAPA_1c55050 1b7b1f09f48061851265d76858b652a3 332 TIGRFAM TIGR00393 kpsF: sugar isomerase, KpsF/GutQ family 53 321 2.9E-109 T 12-10-2018 IPR004800 Phosphosugar isomerase, KdsD/KpsF-type GO:0005975|GO:0016853 VAPA_1c55050 1b7b1f09f48061851265d76858b652a3 332 PIRSF PIRSF004692 6 332 8.8E-128 T 12-10-2018 IPR004800 Phosphosugar isomerase, KdsD/KpsF-type GO:0005975|GO:0016853 VAPA_1c55050 1b7b1f09f48061851265d76858b652a3 332 Pfam PF00571 CBS domain 209 263 2.6E-9 T 12-10-2018 IPR000644 CBS domain VAPA_1c55050 1b7b1f09f48061851265d76858b652a3 332 Pfam PF00571 CBS domain 277 329 7.4E-7 T 12-10-2018 IPR000644 CBS domain VAPA_1c10770 a13c4ab49b410793149a324337b93b24 337 SUPERFAMILY SSF52518 2 220 3.04E-67 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold VAPA_1c10770 a13c4ab49b410793149a324337b93b24 337 SUPERFAMILY SSF52922 205 335 3.8E-40 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 VAPA_1c10770 a13c4ab49b410793149a324337b93b24 337 Gene3D G3DSA:3.40.50.970 1 203 1.6E-90 T 12-10-2018 VAPA_1c10770 a13c4ab49b410793149a324337b93b24 337 Pfam PF02779 Transketolase, pyrimidine binding domain 3 178 4.9E-43 T 12-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain VAPA_1c10770 a13c4ab49b410793149a324337b93b24 337 Pfam PF02780 Transketolase, C-terminal domain 213 327 2.1E-34 T 12-10-2018 IPR033248 Transketolase, C-terminal domain VAPA_1c10770 a13c4ab49b410793149a324337b93b24 337 SMART SM00861 4 179 6.8E-66 T 12-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain VAPA_1c10770 a13c4ab49b410793149a324337b93b24 337 Gene3D G3DSA:3.40.50.920 204 337 1.7E-54 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 VAPA_1c31960 e41b50aee2402fee94dbf1fd93cd2355 317 Gene3D G3DSA:1.10.10.10 8 94 8.1E-20 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c31960 e41b50aee2402fee94dbf1fd93cd2355 317 Pfam PF03466 LysR substrate binding domain 97 298 9.1E-21 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_1c31960 e41b50aee2402fee94dbf1fd93cd2355 317 SUPERFAMILY SSF53850 95 302 4.89E-25 T 12-10-2018 VAPA_1c31960 e41b50aee2402fee94dbf1fd93cd2355 317 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 12 68 1.1E-15 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c31960 e41b50aee2402fee94dbf1fd93cd2355 317 Gene3D G3DSA:3.40.190.290 100 286 5.0E-11 T 12-10-2018 VAPA_1c31960 e41b50aee2402fee94dbf1fd93cd2355 317 SUPERFAMILY SSF46785 7 110 6.43E-19 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c30350 eadec98a96e99d21506bc845bb851ee3 517 PIRSF PIRSF001394 1 511 5.3E-208 T 12-10-2018 IPR011167 Iron-dependent fumarate hydratase GO:0004333|GO:0006091 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384 VAPA_1c30350 eadec98a96e99d21506bc845bb851ee3 517 TIGRFAM TIGR00723 ttdB_fumA_fumB: hydrolyase, tartrate beta subunit/fumarate domain protein, Fe-S type 332 491 7.3E-46 T 12-10-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 VAPA_1c30350 eadec98a96e99d21506bc845bb851ee3 517 TIGRFAM TIGR00722 ttdA_fumA_fumB: hydrolyase, tartrate alpha subunit/fumarate domain protein, Fe-S type 12 291 2.0E-63 T 12-10-2018 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 VAPA_1c30350 eadec98a96e99d21506bc845bb851ee3 517 Pfam PF05681 Fumarate hydratase (Fumerase) 12 290 1.1E-101 T 12-10-2018 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 VAPA_1c30350 eadec98a96e99d21506bc845bb851ee3 517 SUPERFAMILY SSF117457 324 493 2.62E-60 T 12-10-2018 IPR036660 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain superfamily GO:0016836 VAPA_1c30350 eadec98a96e99d21506bc845bb851ee3 517 Gene3D G3DSA:3.20.130.10 314 494 1.8E-56 T 12-10-2018 IPR036660 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain superfamily GO:0016836 VAPA_1c30350 eadec98a96e99d21506bc845bb851ee3 517 Pfam PF05683 Fumarase C-terminus 294 494 4.2E-79 T 12-10-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 VAPA_1c30910 9b6e340b7591afeb762cb9d2ba71eb1e 292 ProSitePatterns PS00567 Phosphoribulokinase signature. 164 177 - T 12-10-2018 IPR006082 Phosphoribulokinase GO:0005524|GO:0005975|GO:0008974 KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 VAPA_1c30910 9b6e340b7591afeb762cb9d2ba71eb1e 292 Gene3D G3DSA:3.40.50.300 1 289 1.1E-115 T 12-10-2018 VAPA_1c30910 9b6e340b7591afeb762cb9d2ba71eb1e 292 SUPERFAMILY SSF52540 4 286 1.27E-44 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c30910 9b6e340b7591afeb762cb9d2ba71eb1e 292 PRINTS PR00478 Phosphoribulokinase family signature 126 144 4.9E-33 T 12-10-2018 IPR006082 Phosphoribulokinase GO:0005524|GO:0005975|GO:0008974 KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 VAPA_1c30910 9b6e340b7591afeb762cb9d2ba71eb1e 292 PRINTS PR00478 Phosphoribulokinase family signature 12 29 4.9E-33 T 12-10-2018 IPR006082 Phosphoribulokinase GO:0005524|GO:0005975|GO:0008974 KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 VAPA_1c30910 9b6e340b7591afeb762cb9d2ba71eb1e 292 PRINTS PR00478 Phosphoribulokinase family signature 164 181 4.9E-33 T 12-10-2018 IPR006082 Phosphoribulokinase GO:0005524|GO:0005975|GO:0008974 KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 VAPA_1c30910 9b6e340b7591afeb762cb9d2ba71eb1e 292 PRINTS PR00478 Phosphoribulokinase family signature 182 205 4.9E-33 T 12-10-2018 IPR006082 Phosphoribulokinase GO:0005524|GO:0005975|GO:0008974 KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 VAPA_1c30910 9b6e340b7591afeb762cb9d2ba71eb1e 292 Pfam PF00485 Phosphoribulokinase / Uridine kinase family 7 214 1.1E-71 T 12-10-2018 IPR006083 Phosphoribulokinase/uridine kinase GO:0005524|GO:0016301 Reactome: R-HSA-73614 VAPA_1c48210 9d482d56c00d21c8f9f0955450e8e88e 304 SUPERFAMILY SSF161111 7 205 2.62E-54 T 12-10-2018 IPR027469 Cation efflux transmembrane domain superfamily VAPA_1c48210 9d482d56c00d21c8f9f0955450e8e88e 304 Gene3D G3DSA:3.30.70.1350 203 295 3.5E-22 T 12-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 VAPA_1c48210 9d482d56c00d21c8f9f0955450e8e88e 304 Gene3D G3DSA:1.20.1510.10 6 202 3.3E-57 T 12-10-2018 IPR027469 Cation efflux transmembrane domain superfamily VAPA_1c48210 9d482d56c00d21c8f9f0955450e8e88e 304 Pfam PF16916 Dimerisation domain of Zinc Transporter 232 289 2.4E-13 T 12-10-2018 IPR027470 Cation efflux protein, cytoplasmic domain VAPA_1c48210 9d482d56c00d21c8f9f0955450e8e88e 304 SUPERFAMILY SSF160240 207 290 2.62E-13 T 12-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 VAPA_1c48210 9d482d56c00d21c8f9f0955450e8e88e 304 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 9 288 7.7E-64 T 12-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 VAPA_1c48210 9d482d56c00d21c8f9f0955450e8e88e 304 Pfam PF01545 Cation efflux family 9 203 3.0E-46 T 12-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 VAPA_1c11700 50bfe8c0e1a071c4aef924533a20dada 223 Gene3D G3DSA:3.20.20.70 1 222 4.6E-58 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 VAPA_1c11700 50bfe8c0e1a071c4aef924533a20dada 223 Pfam PF00923 Transaldolase/Fructose-6-phosphate aldolase 7 208 2.0E-34 T 12-10-2018 IPR001585 Transaldolase/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336|Reactome: R-HSA-8950505 VAPA_1c11700 50bfe8c0e1a071c4aef924533a20dada 223 ProSitePatterns PS01054 Transaldolase signature 1. 28 36 - T 12-10-2018 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336|Reactome: R-HSA-8950505 VAPA_1c11700 50bfe8c0e1a071c4aef924533a20dada 223 SUPERFAMILY SSF51569 7 221 7.12E-50 T 12-10-2018 VAPA_2c12330 c6e1560e5f953f3f8f185146ea290b71 290 Pfam PF02653 Branched-chain amino acid transport system / permease component 8 274 3.1E-39 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 VAPA_1c18820 0b4af3b2bef85ed739f43566d8051031 114 SMART SM00528 69 113 1.7E-11 T 12-10-2018 IPR027444 Histone-like protein H-NS, C-terminal domain GO:0003677 VAPA_1c18820 0b4af3b2bef85ed739f43566d8051031 114 Gene3D G3DSA:4.10.430.10 67 114 2.5E-17 T 12-10-2018 IPR037150 Histone-like protein H-NS, C-terminal domain superfamily GO:0003677 VAPA_1c18820 0b4af3b2bef85ed739f43566d8051031 114 Pfam PF00816 H-NS histone family 16 107 1.4E-24 T 12-10-2018 IPR001801 Histone-like protein H-NS GO:0003677|GO:0005622|GO:0006355 VAPA_1c18820 0b4af3b2bef85ed739f43566d8051031 114 SUPERFAMILY SSF81273 74 113 2.0E-8 T 12-10-2018 VAPA_2c08900 c40956798c33d4eb0335c148a1842fb6 209 TIGRFAM TIGR01755 flav_wrbA: NAD(P)H:quinone oxidoreductase, type IV 5 198 4.6E-49 T 12-10-2018 IPR010089 Flavoprotein WrbA-like GO:0003955|GO:0010181 KEGG: 00130+1.6.5.2|MetaCyc: PWY-7731 VAPA_2c08900 c40956798c33d4eb0335c148a1842fb6 209 Gene3D G3DSA:3.40.50.360 1 203 3.7E-61 T 12-10-2018 IPR029039 Flavoprotein-like superfamily VAPA_2c08900 c40956798c33d4eb0335c148a1842fb6 209 SUPERFAMILY SSF52218 4 198 4.19E-50 T 12-10-2018 IPR029039 Flavoprotein-like superfamily VAPA_2c08900 c40956798c33d4eb0335c148a1842fb6 209 Pfam PF03358 NADPH-dependent FMN reductase 12 132 2.7E-15 T 12-10-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 VAPA_1c03430 0943a4db34867742027b7d12a51f88c2 476 SUPERFAMILY SSF89095 296 401 6.93E-32 T 12-10-2018 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-like GO:0016884 VAPA_1c03430 0943a4db34867742027b7d12a51f88c2 476 Pfam PF02934 GatB/GatE catalytic domain 6 288 1.2E-109 T 12-10-2018 IPR006075 Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic GO:0016874 VAPA_1c03430 0943a4db34867742027b7d12a51f88c2 476 TIGRFAM TIGR00133 gatB: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit 4 475 1.2E-164 T 12-10-2018 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 VAPA_1c03430 0943a4db34867742027b7d12a51f88c2 476 Gene3D G3DSA:1.10.150.380 296 413 1.0E-29 T 12-10-2018 VAPA_1c03430 0943a4db34867742027b7d12a51f88c2 476 Hamap MF_00121 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B [gatB]. 3 476 36.882 T 12-10-2018 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 VAPA_1c03430 0943a4db34867742027b7d12a51f88c2 476 SMART SM00845 327 475 2.4E-74 T 12-10-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 VAPA_1c03430 0943a4db34867742027b7d12a51f88c2 476 Pfam PF02637 GatB domain 327 475 8.7E-51 T 12-10-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 VAPA_1c03430 0943a4db34867742027b7d12a51f88c2 476 SUPERFAMILY SSF55931 5 295 1.18E-115 T 12-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 VAPA_1c03430 0943a4db34867742027b7d12a51f88c2 476 ProSitePatterns PS01234 Glutamyl-tRNA(Gln) amidotransferase subunit B signature. 144 158 - T 12-10-2018 IPR017958 Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site GO:0016884 VAPA_1c03430 0943a4db34867742027b7d12a51f88c2 476 Gene3D G3DSA:1.10.10.410 415 476 1.6E-24 T 12-10-2018 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal VAPA_1c42140 f71466b8678733333df00c8b813621a0 996 Gene3D G3DSA:2.40.40.20 808 996 2.2E-43 T 12-10-2018 VAPA_1c42140 f71466b8678733333df00c8b813621a0 996 Pfam PF01568 Molydopterin dinucleotide binding domain 863 989 2.1E-19 T 12-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 VAPA_1c42140 f71466b8678733333df00c8b813621a0 996 PIRSF PIRSF036643 826 995 4.0E-16 T 12-10-2018 VAPA_1c42140 f71466b8678733333df00c8b813621a0 996 PIRSF PIRSF036643 57 621 3.0E-110 T 12-10-2018 VAPA_1c42140 f71466b8678733333df00c8b813621a0 996 Pfam PF00384 Molybdopterin oxidoreductase 141 595 2.1E-54 T 12-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VAPA_1c42140 f71466b8678733333df00c8b813621a0 996 SUPERFAMILY SSF50692 828 996 1.88E-40 T 12-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily VAPA_1c42140 f71466b8678733333df00c8b813621a0 996 Gene3D G3DSA:3.40.228.10 218 417 1.5E-128 T 12-10-2018 VAPA_1c42140 f71466b8678733333df00c8b813621a0 996 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 87 135 3.6E-9 T 12-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VAPA_1c42140 f71466b8678733333df00c8b813621a0 996 SUPERFAMILY SSF53706 83 645 3.8E-200 T 12-10-2018 VAPA_1c42140 f71466b8678733333df00c8b813621a0 996 SMART SM00926 84 138 2.1E-12 T 12-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VAPA_1c42140 f71466b8678733333df00c8b813621a0 996 Gene3D G3DSA:2.20.25.90 86 137 1.3E-10 T 12-10-2018 VAPA_1c42140 f71466b8678733333df00c8b813621a0 996 Gene3D G3DSA:3.40.50.740 150 647 1.5E-128 T 12-10-2018 VAPA_1c23430 4ca72bbeb0204b2dc94b6d1c5415199d 609 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 269 278 5.8E-68 T 12-10-2018 VAPA_1c23430 4ca72bbeb0204b2dc94b6d1c5415199d 609 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 304 329 5.8E-68 T 12-10-2018 VAPA_1c23430 4ca72bbeb0204b2dc94b6d1c5415199d 609 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 544 559 5.8E-68 T 12-10-2018 VAPA_1c23430 4ca72bbeb0204b2dc94b6d1c5415199d 609 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 128 150 5.8E-68 T 12-10-2018 VAPA_1c23430 4ca72bbeb0204b2dc94b6d1c5415199d 609 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 393 407 5.8E-68 T 12-10-2018 VAPA_1c23430 4ca72bbeb0204b2dc94b6d1c5415199d 609 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 479 500 5.8E-68 T 12-10-2018 VAPA_1c23430 4ca72bbeb0204b2dc94b6d1c5415199d 609 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 161 176 5.8E-68 T 12-10-2018 VAPA_1c23430 4ca72bbeb0204b2dc94b6d1c5415199d 609 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 566 586 5.8E-68 T 12-10-2018 VAPA_1c23430 4ca72bbeb0204b2dc94b6d1c5415199d 609 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 436 443 5.8E-68 T 12-10-2018 VAPA_1c23430 4ca72bbeb0204b2dc94b6d1c5415199d 609 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 162 172 - T 12-10-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 VAPA_1c23430 4ca72bbeb0204b2dc94b6d1c5415199d 609 SUPERFAMILY SSF51905 124 466 7.13E-54 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c23430 4ca72bbeb0204b2dc94b6d1c5415199d 609 Gene3D G3DSA:2.40.50.100 4 82 1.1E-20 T 12-10-2018 VAPA_1c23430 4ca72bbeb0204b2dc94b6d1c5415199d 609 SUPERFAMILY SSF55424 481 602 1.15E-40 T 12-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 VAPA_1c23430 4ca72bbeb0204b2dc94b6d1c5415199d 609 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 128 456 2.1E-54 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 VAPA_1c23430 4ca72bbeb0204b2dc94b6d1c5415199d 609 Pfam PF00364 Biotin-requiring enzyme 5 76 2.6E-22 T 12-10-2018 IPR000089 Biotin/lipoyl attachment VAPA_1c23430 4ca72bbeb0204b2dc94b6d1c5415199d 609 PIRSF PIRSF000350 37 602 4.6E-74 T 12-10-2018 IPR001100 Pyridine nucleotide-disulphide oxidoreductase, class I GO:0009055|GO:0016491 VAPA_1c23430 4ca72bbeb0204b2dc94b6d1c5415199d 609 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 483 591 1.2E-36 T 12-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 VAPA_1c23430 4ca72bbeb0204b2dc94b6d1c5415199d 609 Gene3D G3DSA:3.50.50.60 281 402 2.4E-116 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c23430 4ca72bbeb0204b2dc94b6d1c5415199d 609 Gene3D G3DSA:3.30.390.30 482 603 1.8E-48 T 12-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 VAPA_1c23430 4ca72bbeb0204b2dc94b6d1c5415199d 609 Gene3D G3DSA:3.50.50.60 128 461 2.4E-116 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c23430 4ca72bbeb0204b2dc94b6d1c5415199d 609 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 27 56 - T 12-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 VAPA_1c23430 4ca72bbeb0204b2dc94b6d1c5415199d 609 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 129 148 8.6E-38 T 12-10-2018 VAPA_1c23430 4ca72bbeb0204b2dc94b6d1c5415199d 609 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 392 408 8.6E-38 T 12-10-2018 VAPA_1c23430 4ca72bbeb0204b2dc94b6d1c5415199d 609 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 266 284 8.6E-38 T 12-10-2018 VAPA_1c23430 4ca72bbeb0204b2dc94b6d1c5415199d 609 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 304 322 8.6E-38 T 12-10-2018 VAPA_1c23430 4ca72bbeb0204b2dc94b6d1c5415199d 609 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 421 443 8.6E-38 T 12-10-2018 VAPA_1c23430 4ca72bbeb0204b2dc94b6d1c5415199d 609 SUPERFAMILY SSF51230 4 95 6.89E-24 T 12-10-2018 IPR011053 Single hybrid motif VAPA_1c23430 4ca72bbeb0204b2dc94b6d1c5415199d 609 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 127 597 1.1E-143 T 12-10-2018 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 VAPA_1c07930 25fe088acb7a2c6f5c2a08638f0dfaf3 427 TIGRFAM TIGR03937 PgaC_IcaA: poly-beta-1,6 N-acetyl-D-glucosamine synthase 16 420 7.5E-175 T 12-10-2018 IPR023853 Poly-beta-1,6 N-acetyl-D-glucosamine synthase PgaC/IcaA GO:0008375|GO:0043708 VAPA_1c07930 25fe088acb7a2c6f5c2a08638f0dfaf3 427 Pfam PF13641 Glycosyltransferase like family 2 61 283 1.2E-36 T 12-10-2018 VAPA_1c07930 25fe088acb7a2c6f5c2a08638f0dfaf3 427 SUPERFAMILY SSF53448 56 330 1.18E-62 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases VAPA_1c07930 25fe088acb7a2c6f5c2a08638f0dfaf3 427 Gene3D G3DSA:3.90.550.10 52 271 6.1E-46 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases VAPA_1c46600 488c08a5b5cf851974591b62426ba9ef 389 Pfam PF00549 CoA-ligase 262 379 7.5E-22 T 12-10-2018 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 VAPA_1c46600 488c08a5b5cf851974591b62426ba9ef 389 TIGRFAM TIGR01016 sucCoAbeta: succinate-CoA ligase, beta subunit 1 385 2.2E-154 T 12-10-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 VAPA_1c46600 488c08a5b5cf851974591b62426ba9ef 389 SUPERFAMILY SSF52210 239 385 5.23E-51 T 12-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 VAPA_1c46600 488c08a5b5cf851974591b62426ba9ef 389 Gene3D G3DSA:3.40.50.261 240 387 5.0E-54 T 12-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 VAPA_1c46600 488c08a5b5cf851974591b62426ba9ef 389 Pfam PF08442 ATP-grasp domain 2 202 1.4E-76 T 12-10-2018 IPR013650 ATP-grasp fold, succinyl-CoA synthetase-type KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 VAPA_1c46600 488c08a5b5cf851974591b62426ba9ef 389 PIRSF PIRSF001554 1 388 3.2E-146 T 12-10-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 VAPA_1c46600 488c08a5b5cf851974591b62426ba9ef 389 Hamap MF_00558 Succinate--CoA ligase [ADP-forming] subunit beta [sucC]. 1 386 43.064 T 12-10-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 VAPA_1c46600 488c08a5b5cf851974591b62426ba9ef 389 Gene3D G3DSA:3.30.470.20 1 234 9.1E-95 T 12-10-2018 VAPA_1c46600 488c08a5b5cf851974591b62426ba9ef 389 SUPERFAMILY SSF56059 1 238 6.87E-80 T 12-10-2018 VAPA_1c46600 488c08a5b5cf851974591b62426ba9ef 389 ProSitePatterns PS01217 ATP-citrate lyase / succinyl-CoA ligases family signature 3. 257 281 - T 12-10-2018 IPR017866 Succinyl-CoA synthetase, beta subunit, conserved site KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 VAPA_1c46600 488c08a5b5cf851974591b62426ba9ef 389 Gene3D G3DSA:3.30.1490.20 21 104 9.1E-95 T 12-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 VAPA_1c48880 1cd0b10790cb96bd8cbcccf39b5cd7c2 606 Pfam PF06315 Isocitrate dehydrogenase kinase/phosphatase (AceK) 14 594 2.4E-249 T 12-10-2018 IPR010452 Isocitrate dehydrogenase kinasephosphatase GO:0005737|GO:0006006|GO:0008772|GO:0016791 VAPA_1c48880 1cd0b10790cb96bd8cbcccf39b5cd7c2 606 PIRSF PIRSF000719 5 602 1.3E-228 T 12-10-2018 IPR010452 Isocitrate dehydrogenase kinasephosphatase GO:0005737|GO:0006006|GO:0008772|GO:0016791 VAPA_1c48880 1cd0b10790cb96bd8cbcccf39b5cd7c2 606 ProDom PD043552 KINASE KINASE/PHOSPHATASE ISOCITRATE DEHYDROGENASE 3.1.3.- IDH TRANSFERASE IDHK/P HYDROLASE ENZYME 14 597 0.0 T 12-10-2018 IPR010452 Isocitrate dehydrogenase kinasephosphatase GO:0005737|GO:0006006|GO:0008772|GO:0016791 VAPA_1c48880 1cd0b10790cb96bd8cbcccf39b5cd7c2 606 Hamap MF_00747 Isocitrate dehydrogenase kinase/phosphatase [aceK]. 6 598 44.143 T 12-10-2018 IPR010452 Isocitrate dehydrogenase kinasephosphatase GO:0005737|GO:0006006|GO:0008772|GO:0016791 VAPA_1c44280 ed62ba83163b7af3f39b442c00099d18 447 SUPERFAMILY SSF48239 98 393 8.32E-7 T 12-10-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid VAPA_2c05250 74f408ef9c9af7b807c4071c1b4b76d3 537 Gene3D G3DSA:3.30.410.40 155 476 4.6E-171 T 12-10-2018 VAPA_2c05250 74f408ef9c9af7b807c4071c1b4b76d3 537 PIRSF PIRSF000137 3 537 2.9E-142 T 12-10-2018 IPR012132 Glucose-methanol-choline oxidoreductase GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 VAPA_2c05250 74f408ef9c9af7b807c4071c1b4b76d3 537 Pfam PF00732 GMC oxidoreductase 8 299 1.6E-85 T 12-10-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 VAPA_2c05250 74f408ef9c9af7b807c4071c1b4b76d3 537 Pfam PF05199 GMC oxidoreductase 392 528 7.6E-39 T 12-10-2018 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 VAPA_2c05250 74f408ef9c9af7b807c4071c1b4b76d3 537 Gene3D G3DSA:1.10.1220.110 100 154 4.6E-171 T 12-10-2018 VAPA_2c05250 74f408ef9c9af7b807c4071c1b4b76d3 537 SUPERFAMILY SSF54373 294 479 1.77E-49 T 12-10-2018 VAPA_2c05250 74f408ef9c9af7b807c4071c1b4b76d3 537 ProSitePatterns PS00624 GMC oxidoreductases signature 2. 258 272 - T 12-10-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 VAPA_2c05250 74f408ef9c9af7b807c4071c1b4b76d3 537 Gene3D G3DSA:4.10.450.10 41 200 4.6E-171 T 12-10-2018 IPR027424 Glucose Oxidase, domain 2 KEGG: 00260+1.2.1.8+1.1.99.1|MetaCyc: PWY-3722|MetaCyc: PWY-7494|Reactome: R-HSA-6798163 VAPA_2c05250 74f408ef9c9af7b807c4071c1b4b76d3 537 SUPERFAMILY SSF51905 8 535 2.41E-84 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_2c05250 74f408ef9c9af7b807c4071c1b4b76d3 537 Gene3D G3DSA:3.50.50.60 8 533 4.6E-171 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_2c05250 74f408ef9c9af7b807c4071c1b4b76d3 537 ProSitePatterns PS00623 GMC oxidoreductases signature 1. 85 108 - T 12-10-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 VAPA_2c11070 d1031e1b4e9bdbd6a71cbf4e19755310 273 Gene3D G3DSA:1.10.10.10 42 114 2.1E-17 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_2c11070 d1031e1b4e9bdbd6a71cbf4e19755310 273 Gene3D G3DSA:3.30.450.40 115 190 6.9E-15 T 12-10-2018 IPR029016 GAF-like domain superfamily VAPA_2c11070 d1031e1b4e9bdbd6a71cbf4e19755310 273 Gene3D G3DSA:3.30.450.40 192 263 2.5E-11 T 12-10-2018 IPR029016 GAF-like domain superfamily VAPA_2c11070 d1031e1b4e9bdbd6a71cbf4e19755310 273 SMART SM00346 46 135 1.3E-14 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 VAPA_2c11070 d1031e1b4e9bdbd6a71cbf4e19755310 273 Pfam PF01614 Bacterial transcriptional regulator 198 253 4.4E-6 T 12-10-2018 IPR014757 Transcription regulator IclR, C-terminal VAPA_2c11070 d1031e1b4e9bdbd6a71cbf4e19755310 273 SUPERFAMILY SSF46785 48 118 2.68E-15 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_2c11070 d1031e1b4e9bdbd6a71cbf4e19755310 273 Pfam PF09339 IclR helix-turn-helix domain 49 96 2.4E-11 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 VAPA_2c11070 d1031e1b4e9bdbd6a71cbf4e19755310 273 SUPERFAMILY SSF55781 112 256 1.03E-26 T 12-10-2018 VAPA_1c01340 d449f697939c9c068a74e939886fb661 557 SUPERFAMILY SSF51556 83 501 2.43E-32 T 12-10-2018 IPR032466 Metal-dependent hydrolase VAPA_1c01340 d449f697939c9c068a74e939886fb661 557 Pfam PF07969 Amidohydrolase family 72 541 7.9E-78 T 12-10-2018 IPR013108 Amidohydrolase 3 VAPA_1c01340 d449f697939c9c068a74e939886fb661 557 Gene3D G3DSA:2.30.40.10 31 516 8.3E-84 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 VAPA_1c01340 d449f697939c9c068a74e939886fb661 557 Gene3D G3DSA:3.10.310.70 103 220 8.3E-84 T 12-10-2018 VAPA_1c01340 d449f697939c9c068a74e939886fb661 557 Gene3D G3DSA:3.20.20.140 84 500 8.3E-84 T 12-10-2018 VAPA_1c01340 d449f697939c9c068a74e939886fb661 557 SUPERFAMILY SSF51338 20 545 1.82E-26 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 VAPA_1c33540 82cc603e94b11017f3f8a390f3cc88e2 147 SUPERFAMILY SSF54637 9 134 5.57E-30 T 12-10-2018 IPR029069 HotDog domain superfamily VAPA_1c33540 82cc603e94b11017f3f8a390f3cc88e2 147 Gene3D G3DSA:3.10.129.10 8 145 1.2E-30 T 12-10-2018 VAPA_1c33540 82cc603e94b11017f3f8a390f3cc88e2 147 Pfam PF03061 Thioesterase superfamily 32 104 1.9E-10 T 12-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 VAPA_1c52050 514a915e99ceae0d2ad320c12a8479e4 396 Gene3D G3DSA:3.30.700.10 272 396 1.9E-22 T 12-10-2018 VAPA_1c52050 514a915e99ceae0d2ad320c12a8479e4 396 Pfam PF01435 Peptidase family M48 160 239 6.6E-5 T 12-10-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 VAPA_1c52050 514a915e99ceae0d2ad320c12a8479e4 396 Pfam PF00114 Pilin (bacterial filament) 297 395 9.5E-6 T 12-10-2018 IPR001082 Fimbrial protein pilin GO:0007155|GO:0009289 VAPA_1c52050 514a915e99ceae0d2ad320c12a8479e4 396 Pfam PF01435 Peptidase family M48 69 147 1.9E-9 T 12-10-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 VAPA_1c52050 514a915e99ceae0d2ad320c12a8479e4 396 SUPERFAMILY SSF54523 274 395 6.28E-16 T 12-10-2018 VAPA_1c51860 5390891f80d59b79305ed52d7c81b4cc 222 SUPERFAMILY SSF46785 20 197 3.85E-31 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c51860 5390891f80d59b79305ed52d7c81b4cc 222 ProSitePatterns PS00261 Glycoprotein hormones beta chain signature 1. 178 184 - T 12-10-2018 IPR018245 Gonadotropin, beta subunit, conserved site GO:0005179|GO:0005576 VAPA_1c51860 5390891f80d59b79305ed52d7c81b4cc 222 Gene3D G3DSA:1.10.10.10 13 99 2.8E-9 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c19950 c945959e209a878f60435e37aa554138 399 Gene3D G3DSA:1.20.1250.20 1 389 2.3E-29 T 12-10-2018 VAPA_1c19950 c945959e209a878f60435e37aa554138 399 SUPERFAMILY SSF103473 6 394 1.7E-33 T 12-10-2018 IPR036259 MFS transporter superfamily VAPA_1c19950 c945959e209a878f60435e37aa554138 399 Pfam PF07690 Major Facilitator Superfamily 17 340 2.9E-19 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 VAPA_1c36800 94f8f62e9343e54e6200117eda781429 759 PRINTS PR00941 Cadmium-transporting ATPase signature 62 83 1.2E-10 T 12-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 VAPA_1c36800 94f8f62e9343e54e6200117eda781429 759 PRINTS PR00941 Cadmium-transporting ATPase signature 235 255 1.2E-10 T 12-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 VAPA_1c36800 94f8f62e9343e54e6200117eda781429 759 PRINTS PR00941 Cadmium-transporting ATPase signature 336 350 1.2E-10 T 12-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 VAPA_1c36800 94f8f62e9343e54e6200117eda781429 759 PRINTS PR00941 Cadmium-transporting ATPase signature 181 193 1.2E-10 T 12-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 VAPA_1c36800 94f8f62e9343e54e6200117eda781429 759 PRINTS PR00941 Cadmium-transporting ATPase signature 317 333 1.2E-10 T 12-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 VAPA_1c36800 94f8f62e9343e54e6200117eda781429 759 Gene3D G3DSA:3.40.50.1000 433 701 1.9E-84 T 12-10-2018 IPR023214 HAD superfamily VAPA_1c36800 94f8f62e9343e54e6200117eda781429 759 SUPERFAMILY SSF81665 201 445 2.62E-14 T 12-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 VAPA_1c36800 94f8f62e9343e54e6200117eda781429 759 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 223 734 1.4E-78 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 VAPA_1c36800 94f8f62e9343e54e6200117eda781429 759 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 454 460 - T 12-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 VAPA_1c36800 94f8f62e9343e54e6200117eda781429 759 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 596 606 6.1E-26 T 12-10-2018 VAPA_1c36800 94f8f62e9343e54e6200117eda781429 759 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 301 315 6.1E-26 T 12-10-2018 VAPA_1c36800 94f8f62e9343e54e6200117eda781429 759 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 673 685 6.1E-26 T 12-10-2018 VAPA_1c36800 94f8f62e9343e54e6200117eda781429 759 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 649 668 6.1E-26 T 12-10-2018 VAPA_1c36800 94f8f62e9343e54e6200117eda781429 759 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 452 466 6.1E-26 T 12-10-2018 VAPA_1c36800 94f8f62e9343e54e6200117eda781429 759 Pfam PF00702 haloacid dehalogenase-like hydrolase 449 663 3.9E-37 T 12-10-2018 VAPA_1c36800 94f8f62e9343e54e6200117eda781429 759 SUPERFAMILY SSF81653 259 351 8.11E-24 T 12-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 VAPA_1c36800 94f8f62e9343e54e6200117eda781429 759 Gene3D G3DSA:3.40.1110.10 463 581 1.9E-84 T 12-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 VAPA_1c36800 94f8f62e9343e54e6200117eda781429 759 Gene3D G3DSA:2.70.150.20 244 355 1.2E-35 T 12-10-2018 VAPA_1c36800 94f8f62e9343e54e6200117eda781429 759 TIGRFAM TIGR01512 ATPase-IB2_Cd: cadmium-translocating P-type ATPase 200 754 1.1E-145 T 12-10-2018 VAPA_1c36800 94f8f62e9343e54e6200117eda781429 759 SUPERFAMILY SSF55008 50 115 3.8E-8 T 12-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 VAPA_1c36800 94f8f62e9343e54e6200117eda781429 759 SUPERFAMILY SSF56784 451 749 1.05E-53 T 12-10-2018 IPR036412 HAD-like superfamily VAPA_1c36800 94f8f62e9343e54e6200117eda781429 759 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 200 752 4.1E-179 T 12-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 VAPA_1c36800 94f8f62e9343e54e6200117eda781429 759 Pfam PF00403 Heavy-metal-associated domain 51 109 9.7E-6 T 12-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 VAPA_1c36800 94f8f62e9343e54e6200117eda781429 759 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 182 752 8.0E-122 T 12-10-2018 VAPA_1c36800 94f8f62e9343e54e6200117eda781429 759 Pfam PF00122 E1-E2 ATPase 251 432 3.8E-51 T 12-10-2018 VAPA_1c29780 c013c547c1328336b378f253f99a35f9 355 Gene3D G3DSA:1.10.1530.10 19 344 7.4E-89 T 12-10-2018 VAPA_1c29780 c013c547c1328336b378f253f99a35f9 355 Gene3D G3DSA:3.30.1370.60 73 313 7.4E-89 T 12-10-2018 VAPA_1c29780 c013c547c1328336b378f253f99a35f9 355 SUPERFAMILY SSF89733 8 348 9.81E-82 T 12-10-2018 IPR036111 Malate/L-sulfolactate/L-lactate dehydrogenase-like superfamily GO:0016491|GO:0055114 VAPA_1c29780 c013c547c1328336b378f253f99a35f9 355 Pfam PF02615 Malate/L-lactate dehydrogenase 11 339 2.8E-86 T 12-10-2018 IPR003767 Malate/L-lactate dehydrogenase-like GO:0016491|GO:0055114 VAPA_1c50670 abd52aee97ac5cd1b1ffe5df146ae94e 510 Pfam PF13193 AMP-binding enzyme C-terminal domain 424 498 1.6E-16 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain VAPA_1c50670 abd52aee97ac5cd1b1ffe5df146ae94e 510 SUPERFAMILY SSF56801 7 508 3.92E-130 T 12-10-2018 VAPA_1c50670 abd52aee97ac5cd1b1ffe5df146ae94e 510 Gene3D G3DSA:3.30.300.310 411 509 1.8E-30 T 12-10-2018 VAPA_1c50670 abd52aee97ac5cd1b1ffe5df146ae94e 510 Gene3D G3DSA:3.40.50.12780 6 410 4.7E-94 T 12-10-2018 VAPA_1c50670 abd52aee97ac5cd1b1ffe5df146ae94e 510 Pfam PF00501 AMP-binding enzyme 15 414 5.7E-82 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 VAPA_1c50670 abd52aee97ac5cd1b1ffe5df146ae94e 510 ProSitePatterns PS00455 Putative AMP-binding domain signature. 163 174 - T 12-10-2018 IPR020845 AMP-binding, conserved site VAPA_1c54400 f0659e440976d1e0f0716b3de6e8c5c1 456 Gene3D G3DSA:3.90.1150.10 13 448 1.2E-165 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 VAPA_1c54400 f0659e440976d1e0f0716b3de6e8c5c1 456 SUPERFAMILY SSF53383 13 448 6.47E-119 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase VAPA_1c54400 f0659e440976d1e0f0716b3de6e8c5c1 456 Pfam PF00202 Aminotransferase class-III 32 447 6.7E-99 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 VAPA_1c54400 f0659e440976d1e0f0716b3de6e8c5c1 456 PIRSF PIRSF000521 9 450 3.9E-27 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 VAPA_1c54400 f0659e440976d1e0f0716b3de6e8c5c1 456 Gene3D G3DSA:3.40.640.10 67 346 1.2E-165 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 VAPA_1c54400 f0659e440976d1e0f0716b3de6e8c5c1 456 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 256 293 - T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 VAPA_1c27420 ca9013560374440d13f9ac3a8f20924b 411 TIGRFAM TIGR00858 bioF: 8-amino-7-oxononanoate synthase 24 398 4.8E-131 T 12-10-2018 IPR004723 8-amino-7-oxononanoate synthase, Archaea/Proteobacteria type GO:0008710|GO:0009102 KEGG: 00780+2.3.1.47|MetaCyc: PWY-6519|MetaCyc: PWY-6578|MetaCyc: PWY-7147 VAPA_1c27420 ca9013560374440d13f9ac3a8f20924b 411 Gene3D G3DSA:3.40.640.10 64 297 9.5E-126 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 VAPA_1c27420 ca9013560374440d13f9ac3a8f20924b 411 Pfam PF00155 Aminotransferase class I and II 47 398 2.9E-54 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 VAPA_1c27420 ca9013560374440d13f9ac3a8f20924b 411 Hamap MF_01693 8-amino-7-oxononanoate synthase [bioF]. 4 402 47.909 T 12-10-2018 IPR022834 8-amino-7-oxononanoate synthase, Proteobacteria GO:0008710|GO:0009102 KEGG: 00780+2.3.1.47|MetaCyc: PWY-6519|MetaCyc: PWY-6578|MetaCyc: PWY-7147 VAPA_1c27420 ca9013560374440d13f9ac3a8f20924b 411 Gene3D G3DSA:3.90.1150.10 46 392 9.5E-126 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 VAPA_1c27420 ca9013560374440d13f9ac3a8f20924b 411 SUPERFAMILY SSF53383 10 403 3.46E-97 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase VAPA_1c40080 be8970699ef78b704e6c4077b94bf879 120 Gene3D G3DSA:1.10.760.10 36 117 2.4E-25 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 VAPA_1c40080 be8970699ef78b704e6c4077b94bf879 120 PRINTS PR00606 Class ID cytochrome C signature 79 92 2.0E-14 T 12-10-2018 IPR002324 Cytochrome c, class ID GO:0005506|GO:0009055|GO:0020037 VAPA_1c40080 be8970699ef78b704e6c4077b94bf879 120 PRINTS PR00606 Class ID cytochrome C signature 56 69 2.0E-14 T 12-10-2018 IPR002324 Cytochrome c, class ID GO:0005506|GO:0009055|GO:0020037 VAPA_1c40080 be8970699ef78b704e6c4077b94bf879 120 PRINTS PR00606 Class ID cytochrome C signature 41 54 2.0E-14 T 12-10-2018 IPR002324 Cytochrome c, class ID GO:0005506|GO:0009055|GO:0020037 VAPA_1c40080 be8970699ef78b704e6c4077b94bf879 120 PRINTS PR00606 Class ID cytochrome C signature 106 116 2.0E-14 T 12-10-2018 IPR002324 Cytochrome c, class ID GO:0005506|GO:0009055|GO:0020037 VAPA_1c40080 be8970699ef78b704e6c4077b94bf879 120 Pfam PF00034 Cytochrome c 37 117 8.4E-7 T 12-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 VAPA_1c40080 be8970699ef78b704e6c4077b94bf879 120 SUPERFAMILY SSF46626 39 117 9.9E-16 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 VAPA_1c04840 0c84fe000412c6403534d2ebbe29a40f 139 Gene3D G3DSA:1.10.10.10 1 83 4.6E-31 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c04840 0c84fe000412c6403534d2ebbe29a40f 139 SUPERFAMILY SSF46785 4 134 1.77E-40 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c04840 0c84fe000412c6403534d2ebbe29a40f 139 Pfam PF01475 Ferric uptake regulator family 10 129 2.7E-43 T 12-10-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 VAPA_1c04840 0c84fe000412c6403534d2ebbe29a40f 139 Gene3D G3DSA:3.30.1490.190 85 139 4.3E-22 T 12-10-2018 VAPA_1c11060 48de08eb622a409968d352d9703d3fa6 350 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 61 1.1E-16 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c11060 48de08eb622a409968d352d9703d3fa6 350 Gene3D G3DSA:1.10.10.10 1 88 3.5E-25 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c11060 48de08eb622a409968d352d9703d3fa6 350 Gene3D G3DSA:3.40.190.290 90 295 7.4E-60 T 12-10-2018 VAPA_1c11060 48de08eb622a409968d352d9703d3fa6 350 SUPERFAMILY SSF46785 1 87 2.01E-20 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c11060 48de08eb622a409968d352d9703d3fa6 350 SUPERFAMILY SSF53850 88 299 1.16E-41 T 12-10-2018 VAPA_1c11060 48de08eb622a409968d352d9703d3fa6 350 Pfam PF03466 LysR substrate binding domain 87 293 1.7E-36 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_1c11060 48de08eb622a409968d352d9703d3fa6 350 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 6.5E-5 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c11060 48de08eb622a409968d352d9703d3fa6 350 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 6.5E-5 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c11060 48de08eb622a409968d352d9703d3fa6 350 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 6.5E-5 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_2c11830 45b3d94da1dbdf3ff14699c3cad2647f 293 Gene3D G3DSA:1.10.10.10 1 83 2.2E-24 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_2c11830 45b3d94da1dbdf3ff14699c3cad2647f 293 SUPERFAMILY SSF46785 1 86 1.58E-18 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_2c11830 45b3d94da1dbdf3ff14699c3cad2647f 293 Gene3D G3DSA:3.40.190.290 90 290 2.3E-54 T 12-10-2018 VAPA_2c11830 45b3d94da1dbdf3ff14699c3cad2647f 293 SUPERFAMILY SSF53850 90 289 2.1E-43 T 12-10-2018 VAPA_2c11830 45b3d94da1dbdf3ff14699c3cad2647f 293 Pfam PF03466 LysR substrate binding domain 88 289 2.2E-43 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_2c11830 45b3d94da1dbdf3ff14699c3cad2647f 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.5E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_2c11830 45b3d94da1dbdf3ff14699c3cad2647f 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.5E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_2c11830 45b3d94da1dbdf3ff14699c3cad2647f 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.5E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_2c11830 45b3d94da1dbdf3ff14699c3cad2647f 293 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 4.4E-17 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c20560 6e5289acfcf5471b086d9ca5e7237393 339 SMART SM00972 106 172 0.01 T 12-10-2018 IPR007893 Spore coat protein U VAPA_1c20560 6e5289acfcf5471b086d9ca5e7237393 339 SMART SM00972 277 336 4.9E-20 T 12-10-2018 IPR007893 Spore coat protein U VAPA_1c20560 6e5289acfcf5471b086d9ca5e7237393 339 Pfam PF05229 Spore Coat Protein U domain 200 336 2.4E-28 T 12-10-2018 IPR007893 Spore coat protein U VAPA_1c20560 6e5289acfcf5471b086d9ca5e7237393 339 Pfam PF05229 Spore Coat Protein U domain 28 169 2.1E-14 T 12-10-2018 IPR007893 Spore coat protein U VAPA_1c42260 6cac59d35a9c9dc161be84b101b90b9d 314 SUPERFAMILY SSF46785 6 86 1.54E-17 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c42260 6cac59d35a9c9dc161be84b101b90b9d 314 Pfam PF03466 LysR substrate binding domain 88 297 2.4E-24 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_1c42260 6cac59d35a9c9dc161be84b101b90b9d 314 SUPERFAMILY SSF53850 90 299 4.52E-24 T 12-10-2018 VAPA_1c42260 6cac59d35a9c9dc161be84b101b90b9d 314 Gene3D G3DSA:1.10.10.10 3 85 2.3E-23 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c42260 6cac59d35a9c9dc161be84b101b90b9d 314 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 4.7E-7 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c42260 6cac59d35a9c9dc161be84b101b90b9d 314 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 4.7E-7 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c42260 6cac59d35a9c9dc161be84b101b90b9d 314 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 4.7E-7 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c42260 6cac59d35a9c9dc161be84b101b90b9d 314 Gene3D G3DSA:3.40.190.290 91 302 4.0E-27 T 12-10-2018 VAPA_1c42260 6cac59d35a9c9dc161be84b101b90b9d 314 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 63 1.2E-16 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c02230 be0f9e24b7cbe17bf42b3c3fb41fd14c 386 Gene3D G3DSA:3.40.50.2300 38 374 7.2E-104 T 12-10-2018 VAPA_1c02230 be0f9e24b7cbe17bf42b3c3fb41fd14c 386 Pfam PF13458 Periplasmic binding protein 38 370 1.4E-67 T 12-10-2018 IPR028081 Leucine-binding protein domain VAPA_1c02230 be0f9e24b7cbe17bf42b3c3fb41fd14c 386 SUPERFAMILY SSF53822 38 383 2.94E-71 T 12-10-2018 IPR028082 Periplasmic binding protein-like I VAPA_1c02230 be0f9e24b7cbe17bf42b3c3fb41fd14c 386 Gene3D G3DSA:3.40.50.2300 157 377 7.2E-104 T 12-10-2018 VAPA_1c02230 be0f9e24b7cbe17bf42b3c3fb41fd14c 386 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 60 76 1.1E-6 T 12-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 VAPA_1c02230 be0f9e24b7cbe17bf42b3c3fb41fd14c 386 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 38 54 1.1E-6 T 12-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 VAPA_1c02230 be0f9e24b7cbe17bf42b3c3fb41fd14c 386 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 79 97 1.1E-6 T 12-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 VAPA_2c12740 fc899e4ed57fa7d035e2ebc855115489 377 Pfam PF01498 Transposase 25 75 5.8E-7 T 12-10-2018 IPR002492 Transposase, Tc1-like GO:0003677|GO:0006313|GO:0015074 VAPA_2c12740 fc899e4ed57fa7d035e2ebc855115489 377 Pfam PF13340 Putative transposase of IS4/5 family (DUF4096) 107 180 1.6E-22 T 12-10-2018 IPR025161 Putative transposase IS4/IS5 family VAPA_2c12740 fc899e4ed57fa7d035e2ebc855115489 377 SUPERFAMILY SSF46689 10 65 5.2E-6 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 VAPA_2c12740 fc899e4ed57fa7d035e2ebc855115489 377 Pfam PF01609 Transposase DDE domain 199 361 1.5E-15 T 12-10-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 VAPA_1c25190 28bee786847569c7070a2a3b95cc632e 303 Pfam PF12833 Helix-turn-helix domain 188 265 1.7E-23 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 VAPA_1c25190 28bee786847569c7070a2a3b95cc632e 303 SMART SM00342 181 264 5.9E-27 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 VAPA_1c25190 28bee786847569c7070a2a3b95cc632e 303 SUPERFAMILY SSF46689 218 266 1.48E-12 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 VAPA_1c25190 28bee786847569c7070a2a3b95cc632e 303 Gene3D G3DSA:1.10.10.60 224 279 1.8E-13 T 12-10-2018 VAPA_1c25190 28bee786847569c7070a2a3b95cc632e 303 SUPERFAMILY SSF46689 165 215 3.0E-9 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 VAPA_1c25190 28bee786847569c7070a2a3b95cc632e 303 Gene3D G3DSA:1.10.10.60 162 223 4.8E-14 T 12-10-2018 VAPA_1c25190 28bee786847569c7070a2a3b95cc632e 303 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 248 264 2.8E-5 T 12-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 VAPA_1c25190 28bee786847569c7070a2a3b95cc632e 303 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 233 248 2.8E-5 T 12-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 VAPA_1c00020 63deaf0b3d4a09d248284a820ffa341e 368 Pfam PF02768 DNA polymerase III beta subunit, C-terminal domain 248 367 6.4E-35 T 12-10-2018 IPR022635 DNA polymerase III, beta sliding clamp, C-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 VAPA_1c00020 63deaf0b3d4a09d248284a820ffa341e 368 Gene3D G3DSA:3.10.150.10 2 124 3.2E-34 T 12-10-2018 VAPA_1c00020 63deaf0b3d4a09d248284a820ffa341e 368 TIGRFAM TIGR00663 dnan: DNA polymerase III, beta subunit 7 367 1.8E-95 T 12-10-2018 IPR001001 DNA polymerase III, beta sliding clamp GO:0003677|GO:0006260|GO:0009360 VAPA_1c00020 63deaf0b3d4a09d248284a820ffa341e 368 SMART SM00480 18 364 1.9E-122 T 12-10-2018 IPR001001 DNA polymerase III, beta sliding clamp GO:0003677|GO:0006260|GO:0009360 VAPA_1c00020 63deaf0b3d4a09d248284a820ffa341e 368 SUPERFAMILY SSF55979 247 368 2.47E-38 T 12-10-2018 VAPA_1c00020 63deaf0b3d4a09d248284a820ffa341e 368 Gene3D G3DSA:3.10.150.10 129 249 4.6E-39 T 12-10-2018 VAPA_1c00020 63deaf0b3d4a09d248284a820ffa341e 368 SUPERFAMILY SSF55979 130 246 2.04E-29 T 12-10-2018 VAPA_1c00020 63deaf0b3d4a09d248284a820ffa341e 368 Gene3D G3DSA:3.10.150.10 250 368 7.4E-39 T 12-10-2018 VAPA_1c00020 63deaf0b3d4a09d248284a820ffa341e 368 Pfam PF00712 DNA polymerase III beta subunit, N-terminal domain 7 120 6.4E-27 T 12-10-2018 IPR022634 DNA polymerase III, beta sliding clamp, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 VAPA_1c00020 63deaf0b3d4a09d248284a820ffa341e 368 Pfam PF02767 DNA polymerase III beta subunit, central domain 132 245 8.3E-32 T 12-10-2018 IPR022637 DNA polymerase III, beta sliding clamp, central GO:0003887|GO:0006260|GO:0008408|GO:0009360 VAPA_1c00020 63deaf0b3d4a09d248284a820ffa341e 368 PIRSF PIRSF000804 2 368 2.0E-117 T 12-10-2018 IPR001001 DNA polymerase III, beta sliding clamp GO:0003677|GO:0006260|GO:0009360 VAPA_1c00020 63deaf0b3d4a09d248284a820ffa341e 368 SUPERFAMILY SSF55979 7 121 1.97E-21 T 12-10-2018 VAPA_1c50550 bde9be8cb2390448918f09aeec8cd44a 517 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 154 380 9.7E-74 T 12-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 VAPA_1c50550 bde9be8cb2390448918f09aeec8cd44a 517 Gene3D G3DSA:3.40.50.300 99 387 2.1E-130 T 12-10-2018 VAPA_1c50550 bde9be8cb2390448918f09aeec8cd44a 517 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 27 97 1.5E-14 T 12-10-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 VAPA_1c50550 bde9be8cb2390448918f09aeec8cd44a 517 Gene3D G3DSA:1.20.150.20 388 517 2.8E-46 T 12-10-2018 IPR038376 ATP synthase, alpha subunit, C-terminal domain superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 VAPA_1c50550 bde9be8cb2390448918f09aeec8cd44a 517 Hamap MF_01346 ATP synthase subunit alpha [atpA]. 1 517 49.334 T 12-10-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 VAPA_1c50550 bde9be8cb2390448918f09aeec8cd44a 517 SUPERFAMILY SSF47917 388 516 4.19E-44 T 12-10-2018 VAPA_1c50550 bde9be8cb2390448918f09aeec8cd44a 517 SUPERFAMILY SSF52540 101 386 2.15E-93 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c50550 bde9be8cb2390448918f09aeec8cd44a 517 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 371 380 - T 12-10-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 VAPA_1c50550 bde9be8cb2390448918f09aeec8cd44a 517 Gene3D G3DSA:2.40.30.20 2 98 3.1E-31 T 12-10-2018 IPR023366 ATP synthase subunit alpha, N-terminal domain-like superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 VAPA_1c50550 bde9be8cb2390448918f09aeec8cd44a 517 PIRSF PIRSF039088 1 517 1.9E-235 T 12-10-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 VAPA_1c50550 bde9be8cb2390448918f09aeec8cd44a 517 SUPERFAMILY SSF50615 10 99 2.94E-26 T 12-10-2018 IPR036121 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamily GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 VAPA_1c50550 bde9be8cb2390448918f09aeec8cd44a 517 TIGRFAM TIGR00962 atpA: ATP synthase F1, alpha subunit 3 517 8.4E-245 T 12-10-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 VAPA_1c50550 bde9be8cb2390448918f09aeec8cd44a 517 Pfam PF00306 ATP synthase alpha/beta chain, C terminal domain 387 512 2.7E-43 T 12-10-2018 IPR000793 ATP synthase, alpha subunit, C-terminal GO:0015986 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 VAPA_2c07040 7102266fb777350baf5c3731ba6ac87b 258 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 21 255 1.0E-62 T 12-10-2018 VAPA_2c07040 7102266fb777350baf5c3731ba6ac87b 258 SUPERFAMILY SSF51735 13 257 5.56E-80 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_2c07040 7102266fb777350baf5c3731ba6ac87b 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 163 182 9.6E-44 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c07040 7102266fb777350baf5c3731ba6ac87b 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 16 33 9.6E-44 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c07040 7102266fb777350baf5c3731ba6ac87b 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 90 101 9.6E-44 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c07040 7102266fb777350baf5c3731ba6ac87b 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 219 239 9.6E-44 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c07040 7102266fb777350baf5c3731ba6ac87b 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 184 201 9.6E-44 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c07040 7102266fb777350baf5c3731ba6ac87b 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 137 153 9.6E-44 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c07040 7102266fb777350baf5c3731ba6ac87b 258 Gene3D G3DSA:3.40.50.720 2 255 2.5E-81 T 12-10-2018 VAPA_2c07040 7102266fb777350baf5c3731ba6ac87b 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 163 182 1.7E-14 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c07040 7102266fb777350baf5c3731ba6ac87b 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 143 151 1.7E-14 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c07040 7102266fb777350baf5c3731ba6ac87b 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 90 101 1.7E-14 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c21940 ef06de50e59d3f9e5060cc740b4066c6 260 ProSitePatterns PS00211 ABC transporters family signature. 156 170 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_1c21940 ef06de50e59d3f9e5060cc740b4066c6 260 PIRSF PIRSF039085 17 260 1.3E-106 T 12-10-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 VAPA_1c21940 ef06de50e59d3f9e5060cc740b4066c6 260 Pfam PF00005 ABC transporter 36 184 2.1E-37 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c21940 ef06de50e59d3f9e5060cc740b4066c6 260 SMART SM00382 45 232 2.2E-14 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c21940 ef06de50e59d3f9e5060cc740b4066c6 260 SUPERFAMILY SSF52540 21 254 9.41E-80 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c21940 ef06de50e59d3f9e5060cc740b4066c6 260 Gene3D G3DSA:3.40.50.300 19 260 3.5E-76 T 12-10-2018 VAPA_1c07260 6033cf41ff6383e85d44595b45112426 352 Pfam PF01212 Beta-eliminating lyase 9 298 1.6E-86 T 12-10-2018 IPR001597 Aromatic amino acid beta-eliminating lyase/threonine aldolase GO:0006520|GO:0016829 Reactome: R-HSA-6783984 VAPA_1c07260 6033cf41ff6383e85d44595b45112426 352 Gene3D G3DSA:3.90.1150.10 260 352 7.5E-24 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 VAPA_1c07260 6033cf41ff6383e85d44595b45112426 352 PIRSF PIRSF017617 1 352 2.7E-124 T 12-10-2018 IPR023603 Threonine aldolase VAPA_1c07260 6033cf41ff6383e85d44595b45112426 352 SUPERFAMILY SSF53383 8 350 1.09E-105 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase VAPA_1c07260 6033cf41ff6383e85d44595b45112426 352 Gene3D G3DSA:3.40.640.10 4 259 3.0E-95 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 VAPA_2c04740 d0775c2d49c6bdf0ac7b76eb49a1b3da 451 SUPERFAMILY SSF55103 156 435 8.5E-5 T 12-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 VAPA_2c04740 d0775c2d49c6bdf0ac7b76eb49a1b3da 451 SUPERFAMILY SSF56176 34 173 7.01E-26 T 12-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 VAPA_2c04740 d0775c2d49c6bdf0ac7b76eb49a1b3da 451 Gene3D G3DSA:3.30.465.10 53 174 1.9E-26 T 12-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 VAPA_2c04740 d0775c2d49c6bdf0ac7b76eb49a1b3da 451 Pfam PF01565 FAD binding domain 41 140 9.1E-14 T 12-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 VAPA_1c25180 557b585e4bf511dce76b3a243bf3dd84 776 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 26 146 2.9E-28 T 12-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead VAPA_1c25180 557b585e4bf511dce76b3a243bf3dd84 776 Gene3D G3DSA:3.30.365.10 472 618 1.8E-116 T 12-10-2018 VAPA_1c25180 557b585e4bf511dce76b3a243bf3dd84 776 Gene3D G3DSA:3.30.365.10 147 377 1.0E-112 T 12-10-2018 VAPA_1c25180 557b585e4bf511dce76b3a243bf3dd84 776 Gene3D G3DSA:3.30.365.10 385 746 1.8E-116 T 12-10-2018 VAPA_1c25180 557b585e4bf511dce76b3a243bf3dd84 776 Gene3D G3DSA:3.30.365.10 26 299 1.0E-112 T 12-10-2018 VAPA_1c25180 557b585e4bf511dce76b3a243bf3dd84 776 Gene3D G3DSA:3.90.1170.50 41 146 1.0E-112 T 12-10-2018 VAPA_1c25180 557b585e4bf511dce76b3a243bf3dd84 776 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 165 701 9.9E-160 T 12-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 VAPA_1c25180 557b585e4bf511dce76b3a243bf3dd84 776 SMART SM01008 26 146 9.8E-51 T 12-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead VAPA_1c25180 557b585e4bf511dce76b3a243bf3dd84 776 SUPERFAMILY SSF56003 138 773 2.75E-181 T 12-10-2018 IPR037165 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain superfamily GO:0016491|GO:0055114 VAPA_1c25180 557b585e4bf511dce76b3a243bf3dd84 776 SUPERFAMILY SSF54665 6 167 1.11E-43 T 12-10-2018 IPR036856 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead superfamily VAPA_1c09310 c689547ec8e69c6484433d20e2efbede 315 Pfam PF13437 HlyD family secretion protein 163 244 3.9E-9 T 12-10-2018 VAPA_1c09310 c689547ec8e69c6484433d20e2efbede 315 Gene3D G3DSA:2.40.50.100 53 125 7.0E-10 T 12-10-2018 VAPA_1c09310 c689547ec8e69c6484433d20e2efbede 315 Pfam PF13533 Biotin-lipoyl like 54 102 9.0E-16 T 12-10-2018 IPR039562 Membrane fusion protein, biotin-lipoyl like domain VAPA_1c09310 c689547ec8e69c6484433d20e2efbede 315 SUPERFAMILY SSF111369 49 191 5.23E-20 T 12-10-2018 VAPA_1c09310 c689547ec8e69c6484433d20e2efbede 315 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 53 239 7.6E-31 T 12-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 VAPA_1c09310 c689547ec8e69c6484433d20e2efbede 315 Gene3D G3DSA:2.40.30.170 176 299 6.6E-26 T 12-10-2018 VAPA_1c18940 f6e82520face57b6051d15b791216361 232 Pfam PF03544 Gram-negative bacterial TonB protein C-terminal 152 231 1.7E-15 T 12-10-2018 IPR037682 TonB, C-terminal GO:0055085 VAPA_1c18940 f6e82520face57b6051d15b791216361 232 SUPERFAMILY SSF74653 144 227 1.22E-14 T 12-10-2018 VAPA_1c18940 f6e82520face57b6051d15b791216361 232 TIGRFAM TIGR01352 tonB_Cterm: TonB family C-terminal domain 155 232 7.5E-14 T 12-10-2018 IPR006260 TonB/TolA, C-terminal VAPA_1c18940 f6e82520face57b6051d15b791216361 232 Gene3D G3DSA:3.30.1150.10 105 232 1.8E-18 T 12-10-2018 VAPA_1c18940 f6e82520face57b6051d15b791216361 232 PRINTS PR01217 Proline rich extensin signature 111 132 7.9E-10 T 12-10-2018 VAPA_1c18940 f6e82520face57b6051d15b791216361 232 PRINTS PR01217 Proline rich extensin signature 57 69 7.9E-10 T 12-10-2018 VAPA_1c18940 f6e82520face57b6051d15b791216361 232 PRINTS PR01217 Proline rich extensin signature 71 87 7.9E-10 T 12-10-2018 VAPA_1c18940 f6e82520face57b6051d15b791216361 232 PRINTS PR01217 Proline rich extensin signature 99 111 7.9E-10 T 12-10-2018 VAPA_1c17740 a7eae8fe029d899aa04178219d0c27e7 218 Pfam PF13417 Glutathione S-transferase, N-terminal domain 14 81 1.9E-7 T 12-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 VAPA_1c17740 a7eae8fe029d899aa04178219d0c27e7 218 Gene3D G3DSA:1.20.1050.10 85 194 5.3E-48 T 12-10-2018 VAPA_1c17740 a7eae8fe029d899aa04178219d0c27e7 218 SUPERFAMILY SSF52833 6 87 5.25E-13 T 12-10-2018 IPR036249 Thioredoxin-like superfamily VAPA_1c17740 a7eae8fe029d899aa04178219d0c27e7 218 Gene3D G3DSA:3.40.30.10 6 201 5.3E-48 T 12-10-2018 VAPA_1c17740 a7eae8fe029d899aa04178219d0c27e7 218 Pfam PF13410 Glutathione S-transferase, C-terminal domain 129 202 1.3E-7 T 12-10-2018 VAPA_1c17740 a7eae8fe029d899aa04178219d0c27e7 218 SUPERFAMILY SSF47616 85 204 5.05E-21 T 12-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily VAPA_2c06400 fba8586e04c5f0cc26fefd165b5d963e 76 Gene3D G3DSA:3.40.190.150 1 76 3.9E-18 T 12-10-2018 VAPA_2c06400 fba8586e04c5f0cc26fefd165b5d963e 76 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 1 71 1.0E-6 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_2c03950 a50058a635348648ffec2a60cf1d7dde 484 Gene3D G3DSA:2.20.200.10 110 362 5.5E-124 T 12-10-2018 VAPA_2c03950 a50058a635348648ffec2a60cf1d7dde 484 Pfam PF02321 Outer membrane efflux protein 293 467 1.4E-26 T 12-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 VAPA_2c03950 a50058a635348648ffec2a60cf1d7dde 484 Pfam PF02321 Outer membrane efflux protein 73 263 2.6E-22 T 12-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 VAPA_2c03950 a50058a635348648ffec2a60cf1d7dde 484 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 23 473 1.4E-102 T 12-10-2018 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0016020|GO:0022857|GO:0055085 VAPA_2c03950 a50058a635348648ffec2a60cf1d7dde 484 SUPERFAMILY SSF56954 17 474 3.4E-99 T 12-10-2018 VAPA_2c03950 a50058a635348648ffec2a60cf1d7dde 484 Gene3D G3DSA:1.20.1600.10 64 473 5.5E-124 T 12-10-2018 VAPA_1c25070 a1ef992ed80617dc163897b8fd2d375f 594 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 216 352 4.0E-45 T 12-10-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 VAPA_1c25070 a1ef992ed80617dc163897b8fd2d375f 594 Gene3D G3DSA:3.40.50.1220 211 381 9.6E-61 T 12-10-2018 VAPA_1c25070 a1ef992ed80617dc163897b8fd2d375f 594 TIGRFAM TIGR00118 acolac_lg: acetolactate synthase, large subunit, biosynthetic type 26 588 5.7E-248 T 12-10-2018 IPR012846 Acetolactate synthase, large subunit, biosynthetic GO:0000287|GO:0003984|GO:0009082|GO:0030976|GO:0050660 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 VAPA_1c25070 a1ef992ed80617dc163897b8fd2d375f 594 SUPERFAMILY SSF52518 22 195 4.84E-64 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold VAPA_1c25070 a1ef992ed80617dc163897b8fd2d375f 594 SUPERFAMILY SSF52518 394 588 2.56E-65 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold VAPA_1c25070 a1ef992ed80617dc163897b8fd2d375f 594 SUPERFAMILY SSF52467 209 383 6.55E-64 T 12-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily VAPA_1c25070 a1ef992ed80617dc163897b8fd2d375f 594 Gene3D G3DSA:3.40.50.970 386 593 2.7E-63 T 12-10-2018 VAPA_1c25070 a1ef992ed80617dc163897b8fd2d375f 594 Gene3D G3DSA:3.40.50.970 18 199 3.7E-71 T 12-10-2018 VAPA_1c25070 a1ef992ed80617dc163897b8fd2d375f 594 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 27 190 4.0E-58 T 12-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 VAPA_1c25070 a1ef992ed80617dc163897b8fd2d375f 594 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 417 564 1.5E-48 T 12-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 VAPA_1c02170 9f2161bf0b358aa141556828448d7d0b 194 Pfam PF06684 Amino acid synthesis 5 180 4.5E-70 T 12-10-2018 IPR009569 Amino acid synthesis, putative VAPA_1c02170 9f2161bf0b358aa141556828448d7d0b 194 Gene3D G3DSA:3.30.1330.110 1 194 3.6E-74 T 12-10-2018 IPR035936 BB2672 superfamily VAPA_1c02170 9f2161bf0b358aa141556828448d7d0b 194 SUPERFAMILY SSF160519 1 194 1.15E-70 T 12-10-2018 IPR035936 BB2672 superfamily VAPA_2c10030 ee90822e3698efc388690b0e75de2d89 481 Pfam PF07690 Major Facilitator Superfamily 50 435 3.8E-42 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 VAPA_2c10030 ee90822e3698efc388690b0e75de2d89 481 Gene3D G3DSA:1.20.1720.10 43 250 6.2E-39 T 12-10-2018 VAPA_2c10030 ee90822e3698efc388690b0e75de2d89 481 Gene3D G3DSA:1.20.1250.20 285 479 1.0E-20 T 12-10-2018 VAPA_2c10030 ee90822e3698efc388690b0e75de2d89 481 SUPERFAMILY SSF103473 37 473 6.02E-60 T 12-10-2018 IPR036259 MFS transporter superfamily VAPA_1c30980 8da2751aa529f603f779fc78291566db 488 ProSitePatterns PS00157 Ribulose bisphosphate carboxylase large chain active site. 201 209 - T 12-10-2018 IPR020878 Ribulose bisphosphate carboxylase, large chain, active site GO:0000287|GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 VAPA_1c30980 8da2751aa529f603f779fc78291566db 488 Gene3D G3DSA:3.30.70.150 27 153 2.0E-48 T 12-10-2018 IPR036422 RuBisCO large subunit, N-terminal domain superfamily GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 VAPA_1c30980 8da2751aa529f603f779fc78291566db 488 Pfam PF00016 Ribulose bisphosphate carboxylase large chain, catalytic domain 159 466 9.8E-136 T 12-10-2018 IPR000685 Ribulose bisphosphate carboxylase, large subunit, C-terminal GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 VAPA_1c30980 8da2751aa529f603f779fc78291566db 488 Gene3D G3DSA:3.20.20.110 154 471 3.5E-139 T 12-10-2018 IPR036376 Ribulose bisphosphate carboxylase, large subunit, C-terminal domain superfamily GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 VAPA_1c30980 8da2751aa529f603f779fc78291566db 488 Pfam PF02788 Ribulose bisphosphate carboxylase large chain, N-terminal domain 29 149 8.3E-44 T 12-10-2018 IPR017443 Ribulose bisphosphate carboxylase, large subunit, ferrodoxin-like N-terminal GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 VAPA_1c30980 8da2751aa529f603f779fc78291566db 488 SUPERFAMILY SSF51649 155 481 1.05E-146 T 12-10-2018 IPR036376 Ribulose bisphosphate carboxylase, large subunit, C-terminal domain superfamily GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 VAPA_1c30980 8da2751aa529f603f779fc78291566db 488 SUPERFAMILY SSF54966 14 154 3.14E-57 T 12-10-2018 IPR036422 RuBisCO large subunit, N-terminal domain superfamily GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 VAPA_1c30980 8da2751aa529f603f779fc78291566db 488 Hamap MF_01338 Ribulose bisphosphate carboxylase large chain [rbcL]. 13 479 55.744 T 12-10-2018 IPR020888 Ribulose bisphosphate carboxylase large subunit, type I GO:0000287|GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 VAPA_1c13570 5875270dc887dbdfa046ba660c30220b 257 ProSitePatterns PS00211 ABC transporters family signature. 155 169 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_1c13570 5875270dc887dbdfa046ba660c30220b 257 SUPERFAMILY SSF52540 5 253 9.43E-65 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c13570 5875270dc887dbdfa046ba660c30220b 257 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 233 253 1.9E-8 T 12-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal VAPA_1c13570 5875270dc887dbdfa046ba660c30220b 257 Gene3D G3DSA:3.40.50.300 2 255 6.0E-63 T 12-10-2018 VAPA_1c13570 5875270dc887dbdfa046ba660c30220b 257 SMART SM00382 31 230 1.2E-5 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c13570 5875270dc887dbdfa046ba660c30220b 257 Pfam PF00005 ABC transporter 22 182 5.4E-31 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c36040 dc5430cbd3773b241fc4ba9452ad776d 90 Pfam PF10993 Protein of unknown function (DUF2818) 1 86 1.2E-35 T 12-10-2018 IPR016768 Uncharacterised conserved protein UCP019883, membrane VAPA_1c36040 dc5430cbd3773b241fc4ba9452ad776d 90 PIRSF PIRSF019883 1 90 1.2E-32 T 12-10-2018 IPR016768 Uncharacterised conserved protein UCP019883, membrane VAPA_1c21460 b5cd95bc305dbb40a7f631b8a18688c7 324 SUPERFAMILY SSF53850 113 283 2.37E-12 T 12-10-2018 VAPA_1c21460 b5cd95bc305dbb40a7f631b8a18688c7 324 Gene3D G3DSA:3.40.190.150 28 314 1.6E-107 T 12-10-2018 VAPA_1c21460 b5cd95bc305dbb40a7f631b8a18688c7 324 Gene3D G3DSA:3.40.190.10 126 248 1.6E-107 T 12-10-2018 VAPA_1c21460 b5cd95bc305dbb40a7f631b8a18688c7 324 PIRSF PIRSF017082 1 323 2.5E-74 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c21460 b5cd95bc305dbb40a7f631b8a18688c7 324 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 47 319 4.3E-81 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c12470 ee7c8528536975b36359a2bedcb0e4cf 230 Gene3D G3DSA:1.20.144.10 74 160 5.9E-10 T 12-10-2018 VAPA_1c12470 ee7c8528536975b36359a2bedcb0e4cf 230 Pfam PF01569 PAP2 superfamily 69 149 3.2E-11 T 12-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase VAPA_1c12470 ee7c8528536975b36359a2bedcb0e4cf 230 SUPERFAMILY SSF48317 2 151 1.16E-11 T 12-10-2018 IPR036938 Phosphatidic acid phosphatase type 2/haloperoxidase superfamily VAPA_1c11330 ebe93ab68b02dc6cdde8c327bd6604f9 124 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 10 31 5.3E-7 T 12-10-2018 IPR012902 Prokaryotic N-terminal methylation site VAPA_1c11330 ebe93ab68b02dc6cdde8c327bd6604f9 124 TIGRFAM TIGR01707 gspI: type II secretion system protein I 11 109 3.1E-15 T 12-10-2018 IPR010052 Type II secretion system protein I GO:0008565|GO:0015627|GO:0015628 VAPA_1c11330 ebe93ab68b02dc6cdde8c327bd6604f9 124 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 10 30 - T 12-10-2018 IPR012902 Prokaryotic N-terminal methylation site VAPA_1c11330 ebe93ab68b02dc6cdde8c327bd6604f9 124 Pfam PF02501 Type II secretion system (T2SS), protein I 47 122 3.6E-19 T 12-10-2018 IPR003413 Type II secretion system protein I domain GO:0008565|GO:0015627|GO:0015628 VAPA_1c11330 ebe93ab68b02dc6cdde8c327bd6604f9 124 Pfam PF07963 Prokaryotic N-terminal methylation motif 8 30 1.2E-7 T 12-10-2018 IPR012902 Prokaryotic N-terminal methylation site VAPA_1c11330 ebe93ab68b02dc6cdde8c327bd6604f9 124 SUPERFAMILY SSF54523 49 120 1.26E-11 T 12-10-2018 VAPA_1c11330 ebe93ab68b02dc6cdde8c327bd6604f9 124 Gene3D G3DSA:3.30.1300.30 39 122 1.6E-11 T 12-10-2018 VAPA_1c00030 c05e37d9bf09bed682485073dd3796b9 874 SUPERFAMILY SSF56719 451 865 1.2E-83 T 12-10-2018 IPR013760 DNA topoisomerase, type IIA-like domain superfamily GO:0003918|GO:0005524 Reactome: R-HSA-4615885 VAPA_1c00030 c05e37d9bf09bed682485073dd3796b9 874 PRINTS PR01159 DNA gyrase subunit B signature 417 431 1.6E-76 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 VAPA_1c00030 c05e37d9bf09bed682485073dd3796b9 874 PRINTS PR01159 DNA gyrase subunit B signature 431 451 1.6E-76 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 VAPA_1c00030 c05e37d9bf09bed682485073dd3796b9 874 PRINTS PR01159 DNA gyrase subunit B signature 243 256 1.6E-76 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 VAPA_1c00030 c05e37d9bf09bed682485073dd3796b9 874 PRINTS PR01159 DNA gyrase subunit B signature 267 289 1.6E-76 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 VAPA_1c00030 c05e37d9bf09bed682485073dd3796b9 874 PRINTS PR01159 DNA gyrase subunit B signature 527 536 1.6E-76 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 VAPA_1c00030 c05e37d9bf09bed682485073dd3796b9 874 PRINTS PR01159 DNA gyrase subunit B signature 843 859 1.6E-76 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 VAPA_1c00030 c05e37d9bf09bed682485073dd3796b9 874 PRINTS PR01159 DNA gyrase subunit B signature 299 317 1.6E-76 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 VAPA_1c00030 c05e37d9bf09bed682485073dd3796b9 874 PRINTS PR01159 DNA gyrase subunit B signature 827 839 1.6E-76 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 VAPA_1c00030 c05e37d9bf09bed682485073dd3796b9 874 PRINTS PR01159 DNA gyrase subunit B signature 228 243 1.6E-76 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 VAPA_1c00030 c05e37d9bf09bed682485073dd3796b9 874 PRINTS PR01159 DNA gyrase subunit B signature 36 46 1.6E-76 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 VAPA_1c00030 c05e37d9bf09bed682485073dd3796b9 874 PRINTS PR01159 DNA gyrase subunit B signature 369 385 1.6E-76 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 VAPA_1c00030 c05e37d9bf09bed682485073dd3796b9 874 Gene3D G3DSA:3.40.50.670 763 873 2.2E-25 T 12-10-2018 IPR013759 DNA topoisomerase, type IIA, subunit B, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 VAPA_1c00030 c05e37d9bf09bed682485073dd3796b9 874 Pfam PF01751 Toprim domain 476 598 1.8E-17 T 12-10-2018 IPR006171 TOPRIM domain VAPA_1c00030 c05e37d9bf09bed682485073dd3796b9 874 Hamap MF_01898 DNA gyrase subunit B [gyrB]. 33 874 94.618 T 12-10-2018 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 VAPA_1c00030 c05e37d9bf09bed682485073dd3796b9 874 ProSitePatterns PS00177 DNA topoisomerase II signature. 479 487 - T 12-10-2018 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 VAPA_1c00030 c05e37d9bf09bed682485073dd3796b9 874 Gene3D G3DSA:3.40.50.670 455 645 6.9E-72 T 12-10-2018 IPR013759 DNA topoisomerase, type IIA, subunit B, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 VAPA_1c00030 c05e37d9bf09bed682485073dd3796b9 874 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 63 219 3.4E-18 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase VAPA_1c00030 c05e37d9bf09bed682485073dd3796b9 874 SMART SM00433 66 867 9.1E-244 T 12-10-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 VAPA_1c00030 c05e37d9bf09bed682485073dd3796b9 874 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 805 863 3.6E-29 T 12-10-2018 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 VAPA_1c00030 c05e37d9bf09bed682485073dd3796b9 874 TIGRFAM TIGR01059 gyrB: DNA gyrase, B subunit 36 874 2.5E-281 T 12-10-2018 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 VAPA_1c00030 c05e37d9bf09bed682485073dd3796b9 874 PRINTS PR00418 DNA topoisomerase II family signature 148 162 2.2E-67 T 12-10-2018 VAPA_1c00030 c05e37d9bf09bed682485073dd3796b9 874 PRINTS PR00418 DNA topoisomerase II family signature 66 81 2.2E-67 T 12-10-2018 VAPA_1c00030 c05e37d9bf09bed682485073dd3796b9 874 PRINTS PR00418 DNA topoisomerase II family signature 477 491 2.2E-67 T 12-10-2018 VAPA_1c00030 c05e37d9bf09bed682485073dd3796b9 874 PRINTS PR00418 DNA topoisomerase II family signature 572 589 2.2E-67 T 12-10-2018 VAPA_1c00030 c05e37d9bf09bed682485073dd3796b9 874 PRINTS PR00418 DNA topoisomerase II family signature 101 114 2.2E-67 T 12-10-2018 VAPA_1c00030 c05e37d9bf09bed682485073dd3796b9 874 PRINTS PR00418 DNA topoisomerase II family signature 325 338 2.2E-67 T 12-10-2018 VAPA_1c00030 c05e37d9bf09bed682485073dd3796b9 874 PRINTS PR00418 DNA topoisomerase II family signature 592 604 2.2E-67 T 12-10-2018 VAPA_1c00030 c05e37d9bf09bed682485073dd3796b9 874 PRINTS PR00418 DNA topoisomerase II family signature 554 570 2.2E-67 T 12-10-2018 VAPA_1c00030 c05e37d9bf09bed682485073dd3796b9 874 PRINTS PR00418 DNA topoisomerase II family signature 806 822 2.2E-67 T 12-10-2018 VAPA_1c00030 c05e37d9bf09bed682485073dd3796b9 874 SUPERFAMILY SSF55874 36 261 5.74E-62 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_1c00030 c05e37d9bf09bed682485073dd3796b9 874 SUPERFAMILY SSF54211 268 449 1.14E-56 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold VAPA_1c00030 c05e37d9bf09bed682485073dd3796b9 874 Gene3D G3DSA:3.30.230.10 268 449 5.1E-71 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup VAPA_1c00030 c05e37d9bf09bed682485073dd3796b9 874 Pfam PF00204 DNA gyrase B 268 447 3.0E-57 T 12-10-2018 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 VAPA_1c00030 c05e37d9bf09bed682485073dd3796b9 874 SMART SM00387 62 222 2.8E-18 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase VAPA_1c00030 c05e37d9bf09bed682485073dd3796b9 874 Gene3D G3DSA:3.30.565.10 33 267 5.0E-87 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_1c29210 4456951eb3cc252d54e0c55ce809b5fc 259 Gene3D G3DSA:1.10.12.10 204 259 3.3E-21 T 12-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal VAPA_1c29210 4456951eb3cc252d54e0c55ce809b5fc 259 Pfam PF00378 Enoyl-CoA hydratase/isomerase 14 259 4.4E-47 T 12-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 VAPA_1c29210 4456951eb3cc252d54e0c55ce809b5fc 259 Gene3D G3DSA:3.90.226.10 3 203 5.7E-63 T 12-10-2018 VAPA_1c29210 4456951eb3cc252d54e0c55ce809b5fc 259 SUPERFAMILY SSF52096 5 259 3.2E-66 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily VAPA_1c29210 4456951eb3cc252d54e0c55ce809b5fc 259 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 102 122 - T 12-10-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824 VAPA_1c12730 5c733b361b7b7c692807e6e6c40f6e88 129 Gene3D G3DSA:3.30.1330.40 12 129 8.8E-41 T 12-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 VAPA_1c12730 5c733b361b7b7c692807e6e6c40f6e88 129 SUPERFAMILY SSF55298 17 127 5.81E-39 T 12-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 VAPA_1c12730 5c733b361b7b7c692807e6e6c40f6e88 129 TIGRFAM TIGR00004 TIGR00004: reactive intermediate/imine deaminase 18 125 6.6E-33 T 12-10-2018 IPR006056 RidA family Reactome: R-HSA-8849175 VAPA_1c12730 5c733b361b7b7c692807e6e6c40f6e88 129 Pfam PF01042 Endoribonuclease L-PSP 17 125 4.4E-32 T 12-10-2018 IPR006175 YjgF/YER057c/UK114 family Reactome: R-HSA-8849175 VAPA_1c43010 906e1e339191ed38c89c9762aa00a9d9 251 SUPERFAMILY SSF56281 1 237 1.01E-46 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like VAPA_1c43010 906e1e339191ed38c89c9762aa00a9d9 251 Gene3D G3DSA:3.60.15.10 2 245 1.5E-64 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like VAPA_1c43010 906e1e339191ed38c89c9762aa00a9d9 251 SMART SM00849 11 183 1.5E-25 T 12-10-2018 IPR001279 Metallo-beta-lactamase VAPA_1c43010 906e1e339191ed38c89c9762aa00a9d9 251 Pfam PF00753 Metallo-beta-lactamase superfamily 28 183 3.4E-9 T 12-10-2018 IPR001279 Metallo-beta-lactamase VAPA_1c53090 ab654975d0d9eabdb8e37c8242127160 318 Pfam PF07549 SecD/SecF GG Motif 32 59 6.6E-8 T 12-10-2018 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site VAPA_1c53090 ab654975d0d9eabdb8e37c8242127160 318 Gene3D G3DSA:1.20.1640.10 101 299 4.1E-10 T 12-10-2018 VAPA_1c53090 ab654975d0d9eabdb8e37c8242127160 318 Pfam PF02355 Protein export membrane protein 106 291 4.5E-63 T 12-10-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial VAPA_1c53090 ab654975d0d9eabdb8e37c8242127160 318 Hamap MF_01464_B Protein-export membrane protein SecF [secF]. 10 294 28.647 T 12-10-2018 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 VAPA_1c53090 ab654975d0d9eabdb8e37c8242127160 318 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 97 279 8.0E-48 T 12-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial VAPA_1c53090 ab654975d0d9eabdb8e37c8242127160 318 TIGRFAM TIGR00966 3a0501s07: protein-export membrane protein SecF 38 283 3.8E-74 T 12-10-2018 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 VAPA_1c53090 ab654975d0d9eabdb8e37c8242127160 318 SUPERFAMILY SSF82866 72 294 7.85E-42 T 12-10-2018 VAPA_1c53090 ab654975d0d9eabdb8e37c8242127160 318 PRINTS PR01755 Bacterial translocase SecF protein signature 151 165 9.5E-27 T 12-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial VAPA_1c53090 ab654975d0d9eabdb8e37c8242127160 318 PRINTS PR01755 Bacterial translocase SecF protein signature 231 246 9.5E-27 T 12-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial VAPA_1c53090 ab654975d0d9eabdb8e37c8242127160 318 PRINTS PR01755 Bacterial translocase SecF protein signature 199 217 9.5E-27 T 12-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial VAPA_1c53090 ab654975d0d9eabdb8e37c8242127160 318 PRINTS PR01755 Bacterial translocase SecF protein signature 37 52 9.5E-27 T 12-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial VAPA_1c54580 551acfd4c605d3ea139315c138913c7c 456 Gene3D G3DSA:3.90.1300.10 6 455 7.3E-112 T 12-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 VAPA_1c54580 551acfd4c605d3ea139315c138913c7c 456 SUPERFAMILY SSF75304 4 451 1.7E-105 T 12-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 VAPA_1c54580 551acfd4c605d3ea139315c138913c7c 456 Pfam PF01425 Amidase 30 315 1.2E-73 T 12-10-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 VAPA_1c54580 551acfd4c605d3ea139315c138913c7c 456 Pfam PF01425 Amidase 348 445 1.9E-12 T 12-10-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 VAPA_1c07230 0afafd69f7ce96208c9bb94ea9ab4228 500 Pfam PF00425 chorismate binding enzyme 226 484 1.5E-93 T 12-10-2018 IPR015890 Chorismate-utilising enzyme, C-terminal VAPA_1c07230 0afafd69f7ce96208c9bb94ea9ab4228 500 TIGRFAM TIGR00564 trpE_most: anthranilate synthase component I 26 492 6.5E-159 T 12-10-2018 IPR005256 Anthranilate synthase component I, PabB-like GO:0000162|GO:0004049 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 VAPA_1c07230 0afafd69f7ce96208c9bb94ea9ab4228 500 SUPERFAMILY SSF56322 15 493 2.49E-148 T 12-10-2018 IPR005801 ADC synthase GO:0009058 VAPA_1c07230 0afafd69f7ce96208c9bb94ea9ab4228 500 Pfam PF04715 Anthranilate synthase component I, N terminal region 27 177 1.5E-31 T 12-10-2018 IPR006805 Anthranilate synthase component I, N-terminal GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 VAPA_1c07230 0afafd69f7ce96208c9bb94ea9ab4228 500 Gene3D G3DSA:3.60.120.10 2 499 1.1E-168 T 12-10-2018 IPR005801 ADC synthase GO:0009058 VAPA_1c07230 0afafd69f7ce96208c9bb94ea9ab4228 500 PRINTS PR00095 Anthranilate synthase component I signature 346 359 3.4E-23 T 12-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 VAPA_1c07230 0afafd69f7ce96208c9bb94ea9ab4228 500 PRINTS PR00095 Anthranilate synthase component I signature 426 440 3.4E-23 T 12-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 VAPA_1c07230 0afafd69f7ce96208c9bb94ea9ab4228 500 PRINTS PR00095 Anthranilate synthase component I signature 332 345 3.4E-23 T 12-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 VAPA_1c07230 0afafd69f7ce96208c9bb94ea9ab4228 500 PRINTS PR00095 Anthranilate synthase component I signature 441 455 3.4E-23 T 12-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 VAPA_1c11160 f683a25fa09b1e0d51eddb56a99a5866 237 PIRSF PIRSF006293 3 235 7.1E-68 T 12-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 VAPA_1c11160 f683a25fa09b1e0d51eddb56a99a5866 237 Gene3D G3DSA:3.40.50.620 4 236 9.2E-65 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold VAPA_1c11160 f683a25fa09b1e0d51eddb56a99a5866 237 TIGRFAM TIGR00364 TIGR00364: queuosine biosynthesis protein QueC 7 223 3.6E-60 T 12-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 VAPA_1c11160 f683a25fa09b1e0d51eddb56a99a5866 237 Hamap MF_01633 7-cyano-7-deazaguanine synthase [queC]. 5 236 49.333 T 12-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 VAPA_1c11160 f683a25fa09b1e0d51eddb56a99a5866 237 Pfam PF06508 Queuosine biosynthesis protein QueC 7 230 4.4E-72 T 12-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 VAPA_1c11160 f683a25fa09b1e0d51eddb56a99a5866 237 SUPERFAMILY SSF52402 6 230 1.37E-52 T 12-10-2018 VAPA_1c51730 fd34b50175f2bc37a2b81617250c04c5 218 Pfam PF00486 Transcriptional regulatory protein, C terminal 149 215 1.9E-18 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 VAPA_1c51730 fd34b50175f2bc37a2b81617250c04c5 218 Pfam PF00072 Response regulator receiver domain 3 112 2.8E-22 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_1c51730 fd34b50175f2bc37a2b81617250c04c5 218 Gene3D G3DSA:1.10.10.10 124 218 2.6E-24 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c51730 fd34b50175f2bc37a2b81617250c04c5 218 SMART SM00862 145 216 6.9E-20 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 VAPA_1c51730 fd34b50175f2bc37a2b81617250c04c5 218 Gene3D G3DSA:3.40.50.2300 1 121 2.5E-37 T 12-10-2018 VAPA_1c51730 fd34b50175f2bc37a2b81617250c04c5 218 SUPERFAMILY SSF52172 1 122 2.85E-35 T 12-10-2018 IPR011006 CheY-like superfamily VAPA_1c51730 fd34b50175f2bc37a2b81617250c04c5 218 SUPERFAMILY SSF46894 120 216 9.35E-23 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 VAPA_1c51730 fd34b50175f2bc37a2b81617250c04c5 218 SMART SM00448 1 112 1.8E-35 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_2c01440 c7545ac0f037e06e5d916a43f2f961fb 433 Gene3D G3DSA:3.40.190.10 288 390 6.5E-49 T 12-10-2018 VAPA_2c01440 c7545ac0f037e06e5d916a43f2f961fb 433 SUPERFAMILY SSF53850 211 421 4.67E-34 T 12-10-2018 VAPA_2c01440 c7545ac0f037e06e5d916a43f2f961fb 433 SUPERFAMILY SSF46785 123 233 4.67E-16 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_2c01440 c7545ac0f037e06e5d916a43f2f961fb 433 Gene3D G3DSA:1.10.10.10 21 108 7.2E-18 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_2c01440 c7545ac0f037e06e5d916a43f2f961fb 433 Gene3D G3DSA:1.10.10.10 122 211 3.7E-16 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_2c01440 c7545ac0f037e06e5d916a43f2f961fb 433 Pfam PF03466 LysR substrate binding domain 209 417 1.0E-32 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_2c01440 c7545ac0f037e06e5d916a43f2f961fb 433 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 126 183 2.6E-14 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_2c01440 c7545ac0f037e06e5d916a43f2f961fb 433 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 23 82 2.6E-13 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_2c01440 c7545ac0f037e06e5d916a43f2f961fb 433 SUPERFAMILY SSF46785 21 115 4.45E-16 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_2c01440 c7545ac0f037e06e5d916a43f2f961fb 433 Gene3D G3DSA:3.40.190.10 215 407 6.5E-49 T 12-10-2018 VAPA_2c01440 c7545ac0f037e06e5d916a43f2f961fb 433 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 151 161 7.7E-5 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_2c01440 c7545ac0f037e06e5d916a43f2f961fb 433 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 140 151 7.7E-5 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_2c01440 c7545ac0f037e06e5d916a43f2f961fb 433 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 161 172 7.7E-5 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_2c08710 7eca2a8208dc49cc31eed1d964e301bf 901 SMART SM00862 25 103 6.6E-18 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 VAPA_2c08710 7eca2a8208dc49cc31eed1d964e301bf 901 PRINTS PR00364 Disease resistance protein signature 158 173 1.1E-6 T 12-10-2018 VAPA_2c08710 7eca2a8208dc49cc31eed1d964e301bf 901 PRINTS PR00364 Disease resistance protein signature 226 240 1.1E-6 T 12-10-2018 VAPA_2c08710 7eca2a8208dc49cc31eed1d964e301bf 901 PRINTS PR00364 Disease resistance protein signature 332 346 1.1E-6 T 12-10-2018 VAPA_2c08710 7eca2a8208dc49cc31eed1d964e301bf 901 SUPERFAMILY SSF46894 7 104 2.35E-14 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 VAPA_2c08710 7eca2a8208dc49cc31eed1d964e301bf 901 Gene3D G3DSA:3.40.50.300 126 275 4.5E-15 T 12-10-2018 VAPA_2c08710 7eca2a8208dc49cc31eed1d964e301bf 901 Pfam PF13401 AAA domain 157 251 1.3E-6 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_2c08710 7eca2a8208dc49cc31eed1d964e301bf 901 SUPERFAMILY SSF52540 132 393 1.07E-17 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_2c08710 7eca2a8208dc49cc31eed1d964e301bf 901 Pfam PF00486 Transcriptional regulatory protein, C terminal 25 103 1.0E-14 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 VAPA_2c08710 7eca2a8208dc49cc31eed1d964e301bf 901 Gene3D G3DSA:1.10.10.10 4 111 1.9E-18 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c24620 0bcf9245a2c375ce6d30e3b500afd3e2 421 SMART SM00357 52 118 5.6E-16 T 12-10-2018 IPR011129 Cold shock domain GO:0003676 VAPA_1c24620 0bcf9245a2c375ce6d30e3b500afd3e2 421 Pfam PF07497 Rho termination factor, RNA-binding domain 52 125 2.0E-28 T 12-10-2018 IPR011113 Rho termination factor, RNA-binding domain GO:0003723|GO:0006353 VAPA_1c24620 0bcf9245a2c375ce6d30e3b500afd3e2 421 TIGRFAM TIGR00767 rho: transcription termination factor Rho 2 418 2.7E-204 T 12-10-2018 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 VAPA_1c24620 0bcf9245a2c375ce6d30e3b500afd3e2 421 Hamap MF_01884 Transcription termination factor Rho [rho]. 1 420 235.951 T 12-10-2018 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 VAPA_1c24620 0bcf9245a2c375ce6d30e3b500afd3e2 421 Gene3D G3DSA:1.10.720.10 1 46 3.0E-16 T 12-10-2018 VAPA_1c24620 0bcf9245a2c375ce6d30e3b500afd3e2 421 Gene3D G3DSA:2.40.50.140 47 123 1.5E-31 T 12-10-2018 VAPA_1c24620 0bcf9245a2c375ce6d30e3b500afd3e2 421 SMART SM00382 171 356 3.6E-10 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c24620 0bcf9245a2c375ce6d30e3b500afd3e2 421 SUPERFAMILY SSF52540 90 372 3.5E-65 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c24620 0bcf9245a2c375ce6d30e3b500afd3e2 421 SUPERFAMILY SSF68912 1 46 3.92E-11 T 12-10-2018 IPR036269 Rho termination factor, N-terminal domain superfamily VAPA_1c24620 0bcf9245a2c375ce6d30e3b500afd3e2 421 SUPERFAMILY SSF50249 49 125 1.16E-26 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold VAPA_1c24620 0bcf9245a2c375ce6d30e3b500afd3e2 421 SMART SM00959 5 47 8.7E-16 T 12-10-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 VAPA_1c24620 0bcf9245a2c375ce6d30e3b500afd3e2 421 Pfam PF07498 Rho termination factor, N-terminal domain 5 47 4.3E-14 T 12-10-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 VAPA_1c24620 0bcf9245a2c375ce6d30e3b500afd3e2 421 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 161 364 3.2E-21 T 12-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 VAPA_1c24620 0bcf9245a2c375ce6d30e3b500afd3e2 421 Gene3D G3DSA:3.40.50.300 130 418 8.6E-124 T 12-10-2018 VAPA_1c12650 77b68c37e24f44956215b40f4abcc39e 134 Pfam PF12779 YXWGXW repeat (2 copies) 49 74 1.9E-6 T 12-10-2018 IPR024447 YXWGXW repeat VAPA_1c12650 77b68c37e24f44956215b40f4abcc39e 134 Pfam PF12779 YXWGXW repeat (2 copies) 77 102 0.015 T 12-10-2018 IPR024447 YXWGXW repeat VAPA_1c22630 5c2c6dcc914b9271a9c0a333862fee8f 473 SUPERFAMILY SSF53720 4 469 3.27E-139 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 VAPA_1c22630 5c2c6dcc914b9271a9c0a333862fee8f 473 Pfam PF00171 Aldehyde dehydrogenase family 20 468 3.8E-143 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 VAPA_1c22630 5c2c6dcc914b9271a9c0a333862fee8f 473 Gene3D G3DSA:3.40.309.10 247 438 4.7E-153 T 12-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 VAPA_1c22630 5c2c6dcc914b9271a9c0a333862fee8f 473 Gene3D G3DSA:3.40.605.10 23 465 4.7E-153 T 12-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 VAPA_1c22630 5c2c6dcc914b9271a9c0a333862fee8f 473 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 243 250 - T 12-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 VAPA_1c40710 f1bcd32f8ac1bbd1d772467c2b87da9f 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 79 90 9.7E-13 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c40710 f1bcd32f8ac1bbd1d772467c2b87da9f 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 9.7E-13 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c40710 f1bcd32f8ac1bbd1d772467c2b87da9f 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 141 9.7E-13 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c40710 f1bcd32f8ac1bbd1d772467c2b87da9f 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 17 34 1.4E-38 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c40710 f1bcd32f8ac1bbd1d772467c2b87da9f 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 207 227 1.4E-38 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c40710 f1bcd32f8ac1bbd1d772467c2b87da9f 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 1.4E-38 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c40710 f1bcd32f8ac1bbd1d772467c2b87da9f 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 1.4E-38 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c40710 f1bcd32f8ac1bbd1d772467c2b87da9f 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 1.4E-38 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c40710 f1bcd32f8ac1bbd1d772467c2b87da9f 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 1.4E-38 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c40710 f1bcd32f8ac1bbd1d772467c2b87da9f 246 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 140 168 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 VAPA_1c40710 f1bcd32f8ac1bbd1d772467c2b87da9f 246 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 22 242 3.5E-54 T 12-10-2018 VAPA_1c40710 f1bcd32f8ac1bbd1d772467c2b87da9f 246 Gene3D G3DSA:3.40.50.720 5 245 1.9E-70 T 12-10-2018 VAPA_1c40710 f1bcd32f8ac1bbd1d772467c2b87da9f 246 SUPERFAMILY SSF51735 11 243 1.31E-68 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c47910 dd01940cd78a094ddc8708724f0a3fb1 422 PRINTS PR01217 Proline rich extensin signature 164 185 1.4E-9 T 12-10-2018 VAPA_1c47910 dd01940cd78a094ddc8708724f0a3fb1 422 PRINTS PR01217 Proline rich extensin signature 135 151 1.4E-9 T 12-10-2018 VAPA_1c47910 dd01940cd78a094ddc8708724f0a3fb1 422 PRINTS PR01217 Proline rich extensin signature 205 222 1.4E-9 T 12-10-2018 VAPA_1c47910 dd01940cd78a094ddc8708724f0a3fb1 422 PRINTS PR01217 Proline rich extensin signature 230 255 1.4E-9 T 12-10-2018 VAPA_1c00300 94c4b187dde5394997f1783fdff42c34 64 ProSitePatterns PS01047 Heavy-metal-associated domain. 7 36 - T 12-10-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 VAPA_1c00300 94c4b187dde5394997f1783fdff42c34 64 SUPERFAMILY SSF55008 3 63 1.17E-16 T 12-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 VAPA_1c00300 94c4b187dde5394997f1783fdff42c34 64 Pfam PF00403 Heavy-metal-associated domain 5 62 2.0E-12 T 12-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 VAPA_1c00300 94c4b187dde5394997f1783fdff42c34 64 Gene3D G3DSA:3.30.70.100 3 63 4.4E-21 T 12-10-2018 VAPA_1c37920 51f03280f451559fca9e0048eab779b2 326 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 53 321 1.2E-67 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c37920 51f03280f451559fca9e0048eab779b2 326 SUPERFAMILY SSF53850 103 289 1.63E-6 T 12-10-2018 VAPA_1c37920 51f03280f451559fca9e0048eab779b2 326 PIRSF PIRSF017082 1 326 4.0E-66 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c37920 51f03280f451559fca9e0048eab779b2 326 Gene3D G3DSA:3.40.190.10 129 253 1.1E-95 T 12-10-2018 VAPA_1c37920 51f03280f451559fca9e0048eab779b2 326 Gene3D G3DSA:3.40.190.150 32 317 1.1E-95 T 12-10-2018 VAPA_1c32460 9728271e4e3f8a6b5c3ccd4b156af0a7 322 SUPERFAMILY SSF54292 216 320 2.88E-24 T 12-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 VAPA_1c32460 9728271e4e3f8a6b5c3ccd4b156af0a7 322 Gene3D G3DSA:3.10.20.30 227 322 1.4E-22 T 12-10-2018 IPR012675 Beta-grasp domain superfamily VAPA_1c32460 9728271e4e3f8a6b5c3ccd4b156af0a7 322 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 244 312 4.0E-9 T 12-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 VAPA_1c32460 9728271e4e3f8a6b5c3ccd4b156af0a7 322 SUPERFAMILY SSF63380 4 101 1.74E-24 T 12-10-2018 IPR017938 Riboflavin synthase-like beta-barrel VAPA_1c32460 9728271e4e3f8a6b5c3ccd4b156af0a7 322 Pfam PF00175 Oxidoreductase NAD-binding domain 114 207 2.6E-8 T 12-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 VAPA_1c32460 9728271e4e3f8a6b5c3ccd4b156af0a7 322 Gene3D G3DSA:2.40.30.10 2 102 1.8E-25 T 12-10-2018 VAPA_1c32460 9728271e4e3f8a6b5c3ccd4b156af0a7 322 PRINTS PR00409 Phthalate dioxygenase reductase family signature 193 201 8.9E-46 T 12-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 VAPA_1c32460 9728271e4e3f8a6b5c3ccd4b156af0a7 322 PRINTS PR00409 Phthalate dioxygenase reductase family signature 138 147 8.9E-46 T 12-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 VAPA_1c32460 9728271e4e3f8a6b5c3ccd4b156af0a7 322 PRINTS PR00409 Phthalate dioxygenase reductase family signature 91 105 8.9E-46 T 12-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 VAPA_1c32460 9728271e4e3f8a6b5c3ccd4b156af0a7 322 PRINTS PR00409 Phthalate dioxygenase reductase family signature 41 53 8.9E-46 T 12-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 VAPA_1c32460 9728271e4e3f8a6b5c3ccd4b156af0a7 322 PRINTS PR00409 Phthalate dioxygenase reductase family signature 53 67 8.9E-46 T 12-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 VAPA_1c32460 9728271e4e3f8a6b5c3ccd4b156af0a7 322 PRINTS PR00409 Phthalate dioxygenase reductase family signature 77 91 8.9E-46 T 12-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 VAPA_1c32460 9728271e4e3f8a6b5c3ccd4b156af0a7 322 PRINTS PR00409 Phthalate dioxygenase reductase family signature 113 132 8.9E-46 T 12-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 VAPA_1c32460 9728271e4e3f8a6b5c3ccd4b156af0a7 322 PRINTS PR00409 Phthalate dioxygenase reductase family signature 31 41 8.9E-46 T 12-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 VAPA_1c32460 9728271e4e3f8a6b5c3ccd4b156af0a7 322 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 271 279 - T 12-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 VAPA_1c32460 9728271e4e3f8a6b5c3ccd4b156af0a7 322 Gene3D G3DSA:3.40.50.80 103 223 4.1E-26 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain VAPA_1c32460 9728271e4e3f8a6b5c3ccd4b156af0a7 322 SUPERFAMILY SSF52343 99 229 4.06E-28 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain VAPA_2c05520 e2549888503170f1602a3c794695ffcb 305 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 198 215 2.1E-35 T 12-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) VAPA_2c05520 e2549888503170f1602a3c794695ffcb 305 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 92 113 2.1E-35 T 12-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) VAPA_2c05520 e2549888503170f1602a3c794695ffcb 305 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 159 179 2.1E-35 T 12-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) VAPA_2c05520 e2549888503170f1602a3c794695ffcb 305 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 136 158 2.1E-35 T 12-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) VAPA_2c05520 e2549888503170f1602a3c794695ffcb 305 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 240 258 2.1E-35 T 12-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) VAPA_2c05520 e2549888503170f1602a3c794695ffcb 305 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 16 33 2.1E-35 T 12-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) VAPA_2c05520 e2549888503170f1602a3c794695ffcb 305 Gene3D G3DSA:2.120.10.30 2 292 2.2E-85 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like VAPA_2c05520 e2549888503170f1602a3c794695ffcb 305 Pfam PF08450 SMP-30/Gluconolaconase/LRE-like region 15 258 7.6E-74 T 12-10-2018 IPR013658 SMP-30/Gluconolactonase/LRE-like region VAPA_2c05520 e2549888503170f1602a3c794695ffcb 305 SUPERFAMILY SSF63829 9 284 9.16E-58 T 12-10-2018 VAPA_1c26570 21e60760b45cd276884f81eb563d9647 621 Gene3D G3DSA:3.30.2010.10 215 308 4.7E-6 T 12-10-2018 VAPA_1c26570 21e60760b45cd276884f81eb563d9647 621 Pfam PF01435 Peptidase family M48 266 447 4.3E-16 T 12-10-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 VAPA_1c40630 0012532c94ff4d759c336b08b9858f1b 305 PIRSF PIRSF001365 5 304 2.5E-50 T 12-10-2018 IPR002220 DapA-like GO:0016829 VAPA_1c40630 0012532c94ff4d759c336b08b9858f1b 305 Pfam PF00701 Dihydrodipicolinate synthetase family 10 296 6.6E-31 T 12-10-2018 IPR002220 DapA-like GO:0016829 VAPA_1c40630 0012532c94ff4d759c336b08b9858f1b 305 SUPERFAMILY SSF51569 9 299 1.57E-55 T 12-10-2018 VAPA_1c40630 0012532c94ff4d759c336b08b9858f1b 305 Gene3D G3DSA:3.20.20.70 8 299 3.1E-69 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 VAPA_1c40630 0012532c94ff4d759c336b08b9858f1b 305 SMART SM01130 8 299 6.2E-56 T 12-10-2018 IPR002220 DapA-like GO:0016829 VAPA_1c40630 0012532c94ff4d759c336b08b9858f1b 305 PRINTS PR00146 Dihydrodipicolinate synthase signature 42 63 1.2E-7 T 12-10-2018 IPR002220 DapA-like GO:0016829 VAPA_1c40630 0012532c94ff4d759c336b08b9858f1b 305 PRINTS PR00146 Dihydrodipicolinate synthase signature 78 96 1.2E-7 T 12-10-2018 IPR002220 DapA-like GO:0016829 VAPA_1c40630 0012532c94ff4d759c336b08b9858f1b 305 PRINTS PR00146 Dihydrodipicolinate synthase signature 139 156 1.2E-7 T 12-10-2018 IPR002220 DapA-like GO:0016829 VAPA_1c14390 af9ca697d4862a190ad1dc42fc709987 443 Pfam PF02386 Cation transport protein 4 428 1.8E-57 T 12-10-2018 IPR003445 Cation transporter GO:0006812|GO:0008324|GO:0055085 VAPA_1c29240 9ca525a6008687a227ab3aab1a25906b 423 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 255 404 1.9E-38 T 12-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 VAPA_1c29240 9ca525a6008687a227ab3aab1a25906b 423 SUPERFAMILY SSF56645 1 268 3.66E-67 T 12-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 VAPA_1c29240 9ca525a6008687a227ab3aab1a25906b 423 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 8 137 5.3E-15 T 12-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 VAPA_1c29240 9ca525a6008687a227ab3aab1a25906b 423 Gene3D G3DSA:2.40.110.10 141 255 7.3E-51 T 12-10-2018 VAPA_1c29240 9ca525a6008687a227ab3aab1a25906b 423 Gene3D G3DSA:1.20.140.10 256 413 2.5E-41 T 12-10-2018 VAPA_1c29240 9ca525a6008687a227ab3aab1a25906b 423 Gene3D G3DSA:1.10.540.10 1 140 7.9E-51 T 12-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 VAPA_1c29240 9ca525a6008687a227ab3aab1a25906b 423 SUPERFAMILY SSF47203 253 412 1.45E-47 T 12-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 VAPA_1c29240 9ca525a6008687a227ab3aab1a25906b 423 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 142 237 2.0E-22 T 12-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 VAPA_2c11190 136debce765794de7098c55fb326db89 331 PIRSF PIRSF017082 1 330 2.2E-78 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_2c11190 136debce765794de7098c55fb326db89 331 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 55 326 2.3E-90 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_2c11190 136debce765794de7098c55fb326db89 331 Gene3D G3DSA:3.40.190.150 35 321 1.7E-112 T 12-10-2018 VAPA_2c11190 136debce765794de7098c55fb326db89 331 Gene3D G3DSA:3.40.190.10 133 256 1.7E-112 T 12-10-2018 VAPA_2c11190 136debce765794de7098c55fb326db89 331 SUPERFAMILY SSF53850 118 292 1.28E-10 T 12-10-2018 VAPA_1c07210 1eb01b7176431a09fc4898e0164eb74f 242 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 101 212 2.4E-10 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 VAPA_1c07210 1eb01b7176431a09fc4898e0164eb74f 242 TIGRFAM TIGR01449 PGP_bact: phosphoglycolate phosphatase, bacterial 15 238 1.6E-57 T 12-10-2018 IPR006346 2-phosphoglycolate phosphatase-like, prokaryotic GO:0016791 KEGG: 00630+3.1.3.18|MetaCyc: PWY-181 VAPA_1c07210 1eb01b7176431a09fc4898e0164eb74f 242 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 11 22 7.6E-8 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 VAPA_1c07210 1eb01b7176431a09fc4898e0164eb74f 242 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 125 138 7.6E-8 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 VAPA_1c07210 1eb01b7176431a09fc4898e0164eb74f 242 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 201 214 7.6E-8 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 VAPA_1c07210 1eb01b7176431a09fc4898e0164eb74f 242 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 156 172 7.6E-8 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 VAPA_1c07210 1eb01b7176431a09fc4898e0164eb74f 242 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 89 206 6.9E-12 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 VAPA_1c07210 1eb01b7176431a09fc4898e0164eb74f 242 Gene3D G3DSA:3.40.50.1000 15 233 2.6E-55 T 12-10-2018 IPR023214 HAD superfamily VAPA_1c07210 1eb01b7176431a09fc4898e0164eb74f 242 Hamap MF_00495 Phosphoglycolate phosphatase [gph]. 11 242 37.283 T 12-10-2018 IPR037512 Phosphoglycolate phosphatase, prokaryotic GO:0005975|GO:0008967 KEGG: 00630+3.1.3.18|MetaCyc: PWY-181 VAPA_1c07210 1eb01b7176431a09fc4898e0164eb74f 242 SUPERFAMILY SSF56784 11 237 1.33E-54 T 12-10-2018 IPR036412 HAD-like superfamily VAPA_1c07210 1eb01b7176431a09fc4898e0164eb74f 242 Gene3D G3DSA:1.10.150.240 26 111 2.6E-55 T 12-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 VAPA_1c07210 1eb01b7176431a09fc4898e0164eb74f 242 Pfam PF13419 Haloacid dehalogenase-like hydrolase 15 212 8.3E-31 T 12-10-2018 VAPA_1c39270 aab3c1b964e61d223895cfad5c5cefae 981 Gene3D G3DSA:2.40.40.20 780 947 8.7E-26 T 12-10-2018 VAPA_1c39270 aab3c1b964e61d223895cfad5c5cefae 981 SUPERFAMILY SSF50692 790 948 8.82E-32 T 12-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily VAPA_1c39270 aab3c1b964e61d223895cfad5c5cefae 981 Gene3D G3DSA:3.40.50.740 87 175 1.7E-13 T 12-10-2018 VAPA_1c39270 aab3c1b964e61d223895cfad5c5cefae 981 Pfam PF01568 Molydopterin dinucleotide binding domain 805 907 7.7E-12 T 12-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 VAPA_1c39270 aab3c1b964e61d223895cfad5c5cefae 981 Gene3D G3DSA:2.20.25.90 17 86 1.3E-13 T 12-10-2018 VAPA_1c39270 aab3c1b964e61d223895cfad5c5cefae 981 Pfam PF00384 Molybdopterin oxidoreductase 420 644 2.3E-10 T 12-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VAPA_1c39270 aab3c1b964e61d223895cfad5c5cefae 981 Pfam PF00384 Molybdopterin oxidoreductase 84 390 1.8E-23 T 12-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VAPA_1c39270 aab3c1b964e61d223895cfad5c5cefae 981 SMART SM00926 23 82 8.4E-16 T 12-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VAPA_1c39270 aab3c1b964e61d223895cfad5c5cefae 981 Gene3D G3DSA:3.40.50.740 503 660 3.4E-21 T 12-10-2018 VAPA_1c39270 aab3c1b964e61d223895cfad5c5cefae 981 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 24 76 3.2E-11 T 12-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VAPA_1c39270 aab3c1b964e61d223895cfad5c5cefae 981 SUPERFAMILY SSF53706 17 785 5.37E-150 T 12-10-2018 VAPA_1c01630 769641a64d06c52c3fcaef73d4c643da 169 SMART SM00903 21 165 1.3E-57 T 12-10-2018 IPR002563 Flavin reductase like domain GO:0010181 VAPA_1c01630 769641a64d06c52c3fcaef73d4c643da 169 Pfam PF01613 Flavin reductase like domain 23 164 4.7E-32 T 12-10-2018 IPR002563 Flavin reductase like domain GO:0010181 VAPA_1c01630 769641a64d06c52c3fcaef73d4c643da 169 Gene3D G3DSA:2.30.110.10 1 168 2.2E-46 T 12-10-2018 IPR012349 FMN-binding split barrel GO:0048037 VAPA_1c01630 769641a64d06c52c3fcaef73d4c643da 169 SUPERFAMILY SSF50475 12 165 4.56E-48 T 12-10-2018 VAPA_1c23730 cd7c0f51e186bee6faf563b841f73b3d 389 PIRSF PIRSF006809 3 380 1.6E-133 T 12-10-2018 IPR016496 GTPase HflX GO:0005525 VAPA_1c23730 cd7c0f51e186bee6faf563b841f73b3d 389 Pfam PF01926 50S ribosome-binding GTPase 202 321 3.8E-21 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 VAPA_1c23730 cd7c0f51e186bee6faf563b841f73b3d 389 Pfam PF13167 GTP-binding GTPase N-terminal 26 113 5.8E-30 T 12-10-2018 IPR025121 GTPase HflX, N-terminal VAPA_1c23730 cd7c0f51e186bee6faf563b841f73b3d 389 Pfam PF16360 GTP-binding GTPase Middle Region 115 194 7.4E-27 T 12-10-2018 IPR032305 GTP-binding protein, middle domain VAPA_1c23730 cd7c0f51e186bee6faf563b841f73b3d 389 SUPERFAMILY SSF52540 191 370 5.59E-38 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c23730 cd7c0f51e186bee6faf563b841f73b3d 389 Gene3D G3DSA:3.40.50.11060 21 139 5.5E-38 T 12-10-2018 VAPA_1c23730 cd7c0f51e186bee6faf563b841f73b3d 389 TIGRFAM TIGR03156 GTP_HflX: GTP-binding protein HflX 12 367 3.6E-139 T 12-10-2018 IPR016496 GTPase HflX GO:0005525 VAPA_1c23730 cd7c0f51e186bee6faf563b841f73b3d 389 Gene3D G3DSA:3.40.50.300 201 371 5.3E-38 T 12-10-2018 VAPA_1c23730 cd7c0f51e186bee6faf563b841f73b3d 389 Hamap MF_00900 GTPase HflX [hflX]. 28 376 45.077 T 12-10-2018 IPR016496 GTPase HflX GO:0005525 VAPA_1c23730 cd7c0f51e186bee6faf563b841f73b3d 389 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 202 222 3.4E-6 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 VAPA_1c23730 cd7c0f51e186bee6faf563b841f73b3d 389 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 270 288 3.4E-6 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 VAPA_2c07690 af7d05dff514a9acc441ffb5dddc08b6 587 SUPERFAMILY SSF52172 459 580 5.41E-24 T 12-10-2018 IPR011006 CheY-like superfamily VAPA_2c07690 af7d05dff514a9acc441ffb5dddc08b6 587 SUPERFAMILY SSF47384 208 290 4.9E-14 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 VAPA_2c07690 af7d05dff514a9acc441ffb5dddc08b6 587 Gene3D G3DSA:3.40.50.2300 451 586 1.3E-22 T 12-10-2018 VAPA_2c07690 af7d05dff514a9acc441ffb5dddc08b6 587 SMART SM00448 461 577 4.9E-16 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_2c07690 af7d05dff514a9acc441ffb5dddc08b6 587 SMART SM00388 225 290 2.9E-13 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 VAPA_2c07690 af7d05dff514a9acc441ffb5dddc08b6 587 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 339 444 9.7E-19 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase VAPA_2c07690 af7d05dff514a9acc441ffb5dddc08b6 587 Pfam PF00072 Response regulator receiver domain 463 577 1.8E-12 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_2c07690 af7d05dff514a9acc441ffb5dddc08b6 587 SUPERFAMILY SSF55874 279 445 1.07E-36 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_2c07690 af7d05dff514a9acc441ffb5dddc08b6 587 Gene3D G3DSA:3.30.565.10 290 447 1.3E-31 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_2c07690 af7d05dff514a9acc441ffb5dddc08b6 587 Pfam PF00512 His Kinase A (phospho-acceptor) domain 225 290 2.1E-10 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 VAPA_2c07690 af7d05dff514a9acc441ffb5dddc08b6 587 PRINTS PR00344 Bacterial sensor protein C-terminal signature 388 398 7.1E-11 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_2c07690 af7d05dff514a9acc441ffb5dddc08b6 587 PRINTS PR00344 Bacterial sensor protein C-terminal signature 370 384 7.1E-11 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_2c07690 af7d05dff514a9acc441ffb5dddc08b6 587 PRINTS PR00344 Bacterial sensor protein C-terminal signature 405 423 7.1E-11 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_2c07690 af7d05dff514a9acc441ffb5dddc08b6 587 PRINTS PR00344 Bacterial sensor protein C-terminal signature 429 442 7.1E-11 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_2c07690 af7d05dff514a9acc441ffb5dddc08b6 587 Gene3D G3DSA:1.10.287.130 192 288 1.9E-17 T 12-10-2018 VAPA_2c07690 af7d05dff514a9acc441ffb5dddc08b6 587 SMART SM00387 334 445 2.6E-24 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase VAPA_1c07300 b8502ba2eb30d611c7044c1e38834396 235 ProSitePatterns PS00130 Uracil-DNA glycosylase signature. 69 78 - T 12-10-2018 IPR018085 Uracil-DNA glycosylase, active site GO:0006281|GO:0016799 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 VAPA_1c07300 b8502ba2eb30d611c7044c1e38834396 235 Gene3D G3DSA:3.40.470.10 13 235 1.4E-75 T 12-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 VAPA_1c07300 b8502ba2eb30d611c7044c1e38834396 235 Hamap MF_00148 Uracil-DNA glycosylase [ung]. 18 235 32.896 T 12-10-2018 IPR002043 Uracil-DNA glycosylase family 1 GO:0004844|GO:0006281|GO:0006284 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 VAPA_1c07300 b8502ba2eb30d611c7044c1e38834396 235 TIGRFAM TIGR00628 ung: uracil-DNA glycosylase 20 230 1.3E-66 T 12-10-2018 IPR002043 Uracil-DNA glycosylase family 1 GO:0004844|GO:0006281|GO:0006284 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 VAPA_1c07300 b8502ba2eb30d611c7044c1e38834396 235 SMART SM00987 61 228 1.2E-31 T 12-10-2018 VAPA_1c07300 b8502ba2eb30d611c7044c1e38834396 235 SUPERFAMILY SSF52141 17 229 2.4E-72 T 12-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 VAPA_1c07300 b8502ba2eb30d611c7044c1e38834396 235 SMART SM00986 61 228 1.2E-31 T 12-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 VAPA_1c07300 b8502ba2eb30d611c7044c1e38834396 235 Pfam PF03167 Uracil DNA glycosylase superfamily 63 229 4.7E-24 T 12-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 VAPA_1c12440 0e7ff845f3ced94a803b8e75c42300e8 257 Gene3D G3DSA:3.40.1390.30 17 243 1.8E-70 T 12-10-2018 VAPA_1c12440 0e7ff845f3ced94a803b8e75c42300e8 257 TIGRFAM TIGR00486 YbgI_SA1388: dinuclear metal center protein, YbgI/SA1388 family 7 256 3.7E-55 T 12-10-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 VAPA_1c12440 0e7ff845f3ced94a803b8e75c42300e8 257 SUPERFAMILY SSF102705 4 256 1.15E-68 T 12-10-2018 IPR036069 GTP cyclohydrolase 1 type 2/Nif3 superfamily VAPA_1c12440 0e7ff845f3ced94a803b8e75c42300e8 257 Pfam PF01784 NIF3 (NGG1p interacting factor 3) 9 244 6.0E-51 T 12-10-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 VAPA_1c12440 0e7ff845f3ced94a803b8e75c42300e8 257 Gene3D G3DSA:3.40.1390.30 99 228 1.8E-70 T 12-10-2018 VAPA_1c22130 cf997aabda6fa5c7cfdbc9f4110858d0 550 Gene3D G3DSA:3.30.300.310 439 542 6.6E-32 T 12-10-2018 VAPA_1c22130 cf997aabda6fa5c7cfdbc9f4110858d0 550 Pfam PF00501 AMP-binding enzyme 27 443 1.5E-85 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 VAPA_1c22130 cf997aabda6fa5c7cfdbc9f4110858d0 550 ProSitePatterns PS00455 Putative AMP-binding domain signature. 188 199 - T 12-10-2018 IPR020845 AMP-binding, conserved site VAPA_1c22130 cf997aabda6fa5c7cfdbc9f4110858d0 550 Pfam PF13193 AMP-binding enzyme C-terminal domain 452 527 9.4E-20 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain VAPA_1c22130 cf997aabda6fa5c7cfdbc9f4110858d0 550 Gene3D G3DSA:3.40.50.12780 10 438 6.7E-98 T 12-10-2018 VAPA_1c22130 cf997aabda6fa5c7cfdbc9f4110858d0 550 SUPERFAMILY SSF56801 14 537 7.33E-129 T 12-10-2018 VAPA_1c39980 5f51ef090dac378f3f4120de98a7acf5 428 SUPERFAMILY SSF51338 352 422 4.32E-7 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 VAPA_1c39980 5f51ef090dac378f3f4120de98a7acf5 428 Gene3D G3DSA:2.30.40.10 19 424 7.8E-146 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 VAPA_1c39980 5f51ef090dac378f3f4120de98a7acf5 428 Pfam PF01979 Amidohydrolase family 63 421 4.5E-46 T 12-10-2018 IPR006680 Amidohydrolase-related GO:0016787 VAPA_1c39980 5f51ef090dac378f3f4120de98a7acf5 428 Gene3D G3DSA:3.20.20.140 67 388 7.8E-146 T 12-10-2018 VAPA_1c39980 5f51ef090dac378f3f4120de98a7acf5 428 TIGRFAM TIGR02967 guan_deamin: guanine deaminase 21 424 1.6E-141 T 12-10-2018 IPR014311 Guanine deaminase GO:0006147|GO:0008270|GO:0008892 KEGG: 00230+3.5.4.3|MetaCyc: PWY-5497|MetaCyc: PWY-6606|MetaCyc: PWY-6608|MetaCyc: PWY-7442|Reactome: R-HSA-74259 VAPA_1c39980 5f51ef090dac378f3f4120de98a7acf5 428 SUPERFAMILY SSF51556 66 373 3.24E-89 T 12-10-2018 IPR032466 Metal-dependent hydrolase VAPA_1c09610 84fcb7e41972f14425617b4bf2da4771 181 Gene3D G3DSA:3.60.20.10 2 181 1.5E-65 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal VAPA_1c09610 84fcb7e41972f14425617b4bf2da4771 181 Hamap MF_00248 ATP-dependent protease subunit HslV [hslV]. 6 181 41.555 T 12-10-2018 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 VAPA_1c09610 84fcb7e41972f14425617b4bf2da4771 181 SUPERFAMILY SSF56235 3 180 4.89E-57 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal VAPA_1c09610 84fcb7e41972f14425617b4bf2da4771 181 PIRSF PIRSF039093 1 181 1.2E-86 T 12-10-2018 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 VAPA_1c09610 84fcb7e41972f14425617b4bf2da4771 181 Pfam PF00227 Proteasome subunit 5 179 4.0E-20 T 12-10-2018 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 VAPA_1c09610 84fcb7e41972f14425617b4bf2da4771 181 TIGRFAM TIGR03692 ATP_dep_HslV: ATP-dependent protease HslVU, peptidase subunit 7 181 8.5E-84 T 12-10-2018 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 VAPA_2c02920 252be8c24958fcac4c1a3baaac0648d5 232 Gene3D G3DSA:1.10.150.750 20 90 2.2E-57 T 12-10-2018 VAPA_2c02920 252be8c24958fcac4c1a3baaac0648d5 232 Pfam PF13419 Haloacid dehalogenase-like hydrolase 83 194 1.1E-5 T 12-10-2018 VAPA_2c02920 252be8c24958fcac4c1a3baaac0648d5 232 SUPERFAMILY SSF56784 5 228 1.37E-31 T 12-10-2018 IPR036412 HAD-like superfamily VAPA_2c02920 252be8c24958fcac4c1a3baaac0648d5 232 TIGRFAM TIGR01493 HAD-SF-IA-v2: HAD hydrolase, family IA, variant 2 8 185 2.7E-18 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 VAPA_2c02920 252be8c24958fcac4c1a3baaac0648d5 232 Gene3D G3DSA:3.40.50.1000 5 221 2.2E-57 T 12-10-2018 IPR023214 HAD superfamily VAPA_2c06950 81cb298623607c1335c0eeed64e2f22a 347 Pfam PF02653 Branched-chain amino acid transport system / permease component 61 337 4.7E-38 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 VAPA_1c22040 c4c64839b76cf038143841361c144874 357 PIRSF PIRSF036407 7 357 5.2E-113 T 12-10-2018 IPR004536 Selenophosphate synthetase GO:0005524 KEGG: 00450+2.7.9.3|MetaCyc: PWY-6281 VAPA_1c22040 c4c64839b76cf038143841361c144874 357 Pfam PF00586 AIR synthase related protein, N-terminal domain 57 164 4.9E-18 T 12-10-2018 IPR016188 PurM-like, N-terminal domain VAPA_1c22040 c4c64839b76cf038143841361c144874 357 Hamap MF_00625 Selenide, water dikinase [selD]. 12 357 43.506 T 12-10-2018 IPR023061 Selenophosphate synthetase, class I GO:0004756|GO:0005524|GO:0016260 KEGG: 00450+2.7.9.3|MetaCyc: PWY-6281 VAPA_1c22040 c4c64839b76cf038143841361c144874 357 Gene3D G3DSA:3.90.650.10 171 353 3.1E-49 T 12-10-2018 IPR036676 PurM-like, C-terminal domain superfamily VAPA_1c22040 c4c64839b76cf038143841361c144874 357 SUPERFAMILY SSF55326 14 168 2.54E-38 T 12-10-2018 IPR036921 PurM-like, N-terminal domain superfamily VAPA_1c22040 c4c64839b76cf038143841361c144874 357 TIGRFAM TIGR00476 selD: selenide, water dikinase 14 323 3.1E-129 T 12-10-2018 IPR004536 Selenophosphate synthetase GO:0005524 KEGG: 00450+2.7.9.3|MetaCyc: PWY-6281 VAPA_1c22040 c4c64839b76cf038143841361c144874 357 Pfam PF02769 AIR synthase related protein, C-terminal domain 176 349 8.3E-30 T 12-10-2018 IPR010918 PurM-like, C-terminal domain VAPA_1c22040 c4c64839b76cf038143841361c144874 357 SUPERFAMILY SSF56042 171 348 4.34E-45 T 12-10-2018 IPR036676 PurM-like, C-terminal domain superfamily VAPA_1c22040 c4c64839b76cf038143841361c144874 357 Gene3D G3DSA:3.30.1330.10 7 169 2.4E-47 T 12-10-2018 IPR036921 PurM-like, N-terminal domain superfamily VAPA_1c03770 d0b744f90129d8979db971d4672eb686 413 Pfam PF00155 Aminotransferase class I and II 45 405 7.9E-75 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 VAPA_1c03770 d0b744f90129d8979db971d4672eb686 413 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 249 262 - T 12-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 VAPA_1c03770 d0b744f90129d8979db971d4672eb686 413 Gene3D G3DSA:3.90.1150.10 39 405 6.3E-129 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 VAPA_1c03770 d0b744f90129d8979db971d4672eb686 413 SUPERFAMILY SSF53383 18 410 4.81E-108 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase VAPA_1c03770 d0b744f90129d8979db971d4672eb686 413 Gene3D G3DSA:3.40.640.10 76 299 6.3E-129 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 VAPA_1c50740 5529c49bf06e7fcf55b5681b01b39781 234 Gene3D G3DSA:3.40.50.2300 1 125 8.6E-36 T 12-10-2018 VAPA_1c50740 5529c49bf06e7fcf55b5681b01b39781 234 Gene3D G3DSA:1.10.10.10 126 231 7.3E-30 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c50740 5529c49bf06e7fcf55b5681b01b39781 234 Pfam PF00486 Transcriptional regulatory protein, C terminal 154 226 9.1E-21 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 VAPA_1c50740 5529c49bf06e7fcf55b5681b01b39781 234 SMART SM00448 2 112 1.4E-41 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_1c50740 5529c49bf06e7fcf55b5681b01b39781 234 SUPERFAMILY SSF46894 130 227 1.67E-25 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 VAPA_1c50740 5529c49bf06e7fcf55b5681b01b39781 234 Pfam PF00072 Response regulator receiver domain 4 113 1.6E-25 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_1c50740 5529c49bf06e7fcf55b5681b01b39781 234 SUPERFAMILY SSF52172 1 124 9.96E-41 T 12-10-2018 IPR011006 CheY-like superfamily VAPA_1c50740 5529c49bf06e7fcf55b5681b01b39781 234 SMART SM00862 154 226 3.3E-22 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 VAPA_1c50330 b714498caec1c99afe3f23324eb89f9c 899 SMART SM00490 302 383 1.8E-7 T 12-10-2018 IPR001650 Helicase, C-terminal VAPA_1c50330 b714498caec1c99afe3f23324eb89f9c 899 Gene3D G3DSA:3.40.50.300 24 237 5.7E-37 T 12-10-2018 VAPA_1c50330 b714498caec1c99afe3f23324eb89f9c 899 Pfam PF08494 DEAD/H associated 628 820 2.5E-42 T 12-10-2018 IPR013701 DEAD/H associated GO:0005524|GO:0016818 VAPA_1c50330 b714498caec1c99afe3f23324eb89f9c 899 Gene3D G3DSA:3.40.50.300 274 414 3.4E-19 T 12-10-2018 VAPA_1c50330 b714498caec1c99afe3f23324eb89f9c 899 SMART SM00487 34 246 1.2E-22 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain VAPA_1c50330 b714498caec1c99afe3f23324eb89f9c 899 Pfam PF00270 DEAD/DEAH box helicase 40 223 3.6E-22 T 12-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 VAPA_1c50330 b714498caec1c99afe3f23324eb89f9c 899 PIRSF PIRSF037307 14 865 5.3E-144 T 12-10-2018 IPR017170 Lhr-like ATP-dependent RNA helicase, predicted GO:0005524|GO:0016818 VAPA_1c50330 b714498caec1c99afe3f23324eb89f9c 899 SUPERFAMILY SSF52540 45 395 3.73E-42 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c50330 b714498caec1c99afe3f23324eb89f9c 899 TIGRFAM TIGR04121 DEXH_lig_assoc: DEXH box helicase, DNA ligase-associated 27 849 0.0 T 12-10-2018 IPR026362 DEXH box helicase, DNA ligase-associated VAPA_1c50330 b714498caec1c99afe3f23324eb89f9c 899 Pfam PF00271 Helicase conserved C-terminal domain 280 384 1.3E-11 T 12-10-2018 IPR001650 Helicase, C-terminal VAPA_1c00750 f1f35d71fb2f71b1ff0a76de90339168 169 Gene3D G3DSA:3.30.450.40 8 160 1.4E-10 T 12-10-2018 IPR029016 GAF-like domain superfamily VAPA_1c00750 f1f35d71fb2f71b1ff0a76de90339168 169 SUPERFAMILY SSF55781 24 158 2.09E-13 T 12-10-2018 VAPA_1c12120 bab74820cb551a107e20c9e5458ef42f 497 Gene3D G3DSA:3.50.50.60 261 419 2.0E-37 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c12120 bab74820cb551a107e20c9e5458ef42f 497 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 144 478 1.7E-27 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 VAPA_1c12120 bab74820cb551a107e20c9e5458ef42f 497 SUPERFAMILY SSF51971 142 420 1.53E-65 T 12-10-2018 VAPA_1c12120 bab74820cb551a107e20c9e5458ef42f 497 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 23 131 1.7E-25 T 12-10-2018 IPR028261 Dihydroprymidine dehydrogenase domain II Reactome: R-HSA-73621 VAPA_1c12120 bab74820cb551a107e20c9e5458ef42f 497 TIGRFAM TIGR01317 GOGAT_sm_gam: glutamate synthase, NADH/NADPH, small subunit 3 496 7.1E-225 T 12-10-2018 IPR006005 Glutamate synthase, NADH/NADPH, small subunit 1 GO:0006537|GO:0016639|GO:0055114 VAPA_1c12120 bab74820cb551a107e20c9e5458ef42f 497 Gene3D G3DSA:1.10.1060.10 9 141 1.1E-23 T 12-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 VAPA_1c12120 bab74820cb551a107e20c9e5458ef42f 497 SUPERFAMILY SSF46548 2 154 1.12E-39 T 12-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 VAPA_1c12120 bab74820cb551a107e20c9e5458ef42f 497 SUPERFAMILY SSF51971 390 490 2.82E-10 T 12-10-2018 VAPA_1c12120 bab74820cb551a107e20c9e5458ef42f 497 PRINTS PR00419 Adrenodoxin reductase family signature 301 315 3.5E-20 T 12-10-2018 VAPA_1c12120 bab74820cb551a107e20c9e5458ef42f 497 PRINTS PR00419 Adrenodoxin reductase family signature 168 181 3.5E-20 T 12-10-2018 VAPA_1c12120 bab74820cb551a107e20c9e5458ef42f 497 PRINTS PR00419 Adrenodoxin reductase family signature 145 167 3.5E-20 T 12-10-2018 VAPA_1c12120 bab74820cb551a107e20c9e5458ef42f 497 Gene3D G3DSA:3.40.50.720 142 260 1.7E-17 T 12-10-2018 VAPA_1c33090 041fa9334c617ce9fd08e2cab383522c 375 SUPERFAMILY SSF56935 21 375 1.59E-59 T 12-10-2018 VAPA_1c33090 041fa9334c617ce9fd08e2cab383522c 375 Gene3D G3DSA:2.40.160.10 21 375 2.6E-71 T 12-10-2018 IPR023614 Porin domain superfamily VAPA_1c33090 041fa9334c617ce9fd08e2cab383522c 375 Pfam PF13609 Gram-negative porin 8 345 6.4E-56 T 12-10-2018 VAPA_1c04390 b4a75708b68ee9a9a088b1c1ca3f472f 202 SUPERFAMILY SSF53335 7 186 1.49E-17 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase VAPA_1c04390 b4a75708b68ee9a9a088b1c1ca3f472f 202 Gene3D G3DSA:3.40.50.150 8 198 2.7E-29 T 12-10-2018 VAPA_1c03290 3f0e936a27f43a4efe1aadcfb45f2bdb 372 Gene3D G3DSA:3.40.50.2300 39 299 5.8E-102 T 12-10-2018 VAPA_1c03290 3f0e936a27f43a4efe1aadcfb45f2bdb 372 Gene3D G3DSA:3.40.50.2300 145 364 5.8E-102 T 12-10-2018 VAPA_1c03290 3f0e936a27f43a4efe1aadcfb45f2bdb 372 Pfam PF02608 ABC transporter substrate-binding protein PnrA-like 38 329 2.5E-41 T 12-10-2018 IPR003760 ABC transporter substrate-binding protein PnrA-like GO:0005886 VAPA_1c28400 72cff3d809045ffae6d5a6c212f13246 329 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 25 85 5.8E-11 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 VAPA_1c28400 72cff3d809045ffae6d5a6c212f13246 329 Pfam PF13602 Zinc-binding dehydrogenase 195 324 3.1E-22 T 12-10-2018 VAPA_1c28400 72cff3d809045ffae6d5a6c212f13246 329 Gene3D G3DSA:3.90.180.10 17 312 1.4E-103 T 12-10-2018 VAPA_1c28400 72cff3d809045ffae6d5a6c212f13246 329 SMART SM00829 10 324 3.7E-34 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 VAPA_1c28400 72cff3d809045ffae6d5a6c212f13246 329 Gene3D G3DSA:3.40.50.720 124 293 1.4E-103 T 12-10-2018 VAPA_1c28400 72cff3d809045ffae6d5a6c212f13246 329 SUPERFAMILY SSF50129 1 148 1.67E-39 T 12-10-2018 IPR011032 GroES-like superfamily VAPA_1c28400 72cff3d809045ffae6d5a6c212f13246 329 SUPERFAMILY SSF51735 116 292 8.98E-35 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c36160 35ad1edcf68c1e63f3d0f2787986aa13 203 TIGRFAM TIGR01961 NuoC_fam: NADH (or F420H2) dehydrogenase, subunit C 37 162 7.4E-39 T 12-10-2018 IPR010218 NADH dehydrogenase, subunit C GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VAPA_1c36160 35ad1edcf68c1e63f3d0f2787986aa13 203 ProDom PD001581 OXIDOREDUCTASE SUBUNIT NADH DEHYDROGENASE CHAIN C NAD DEHYDROGENASE UBIQUINONE F420H2 90 151 5.0E-25 T 12-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VAPA_1c36160 35ad1edcf68c1e63f3d0f2787986aa13 203 Pfam PF00329 Respiratory-chain NADH dehydrogenase, 30 Kd subunit 36 164 4.1E-41 T 12-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VAPA_1c36160 35ad1edcf68c1e63f3d0f2787986aa13 203 ProSitePatterns PS00542 Respiratory chain NADH dehydrogenase 30 Kd subunit signature. 124 145 - T 12-10-2018 IPR020396 NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VAPA_1c36160 35ad1edcf68c1e63f3d0f2787986aa13 203 SUPERFAMILY SSF143243 13 185 1.83E-53 T 12-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VAPA_1c36160 35ad1edcf68c1e63f3d0f2787986aa13 203 Gene3D G3DSA:3.30.460.80 5 143 1.7E-39 T 12-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VAPA_1c36160 35ad1edcf68c1e63f3d0f2787986aa13 203 Hamap MF_01357 NAD(P)H-quinone oxidoreductase subunit J, chloroplastic [ndhJ]. 11 171 33.134 T 12-10-2018 IPR010218 NADH dehydrogenase, subunit C GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VAPA_2c07000 15ab9fa38a7e218196ced7d7fdcb343c 236 SUPERFAMILY SSF52540 2 233 1.08E-62 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_2c07000 15ab9fa38a7e218196ced7d7fdcb343c 236 SMART SM00382 26 227 9.0E-10 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_2c07000 15ab9fa38a7e218196ced7d7fdcb343c 236 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_2c07000 15ab9fa38a7e218196ced7d7fdcb343c 236 PIRSF PIRSF039137 1 236 7.5E-104 T 12-10-2018 IPR030660 High-affinity branched-chain amino acid transport ATP-binding protein GO:0015658|GO:0015803 VAPA_2c07000 15ab9fa38a7e218196ced7d7fdcb343c 236 Gene3D G3DSA:3.40.50.300 1 236 2.6E-66 T 12-10-2018 VAPA_2c07000 15ab9fa38a7e218196ced7d7fdcb343c 236 Pfam PF00005 ABC transporter 18 163 4.5E-33 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c15300 87b60a1d98f85d866f065d36df084c09 792 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 339 486 4.6E-17 T 12-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 VAPA_1c15300 87b60a1d98f85d866f065d36df084c09 792 Gene3D G3DSA:2.40.110.10 216 338 3.7E-95 T 12-10-2018 VAPA_1c15300 87b60a1d98f85d866f065d36df084c09 792 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 106 212 1.3E-18 T 12-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 VAPA_1c15300 87b60a1d98f85d866f065d36df084c09 792 Gene3D G3DSA:1.20.140.10 339 486 3.7E-95 T 12-10-2018 VAPA_1c15300 87b60a1d98f85d866f065d36df084c09 792 SUPERFAMILY SSF47203 339 486 8.38E-27 T 12-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 VAPA_1c15300 87b60a1d98f85d866f065d36df084c09 792 Pfam PF09317 Domain of unknown function (DUF1974) 493 719 2.2E-38 T 12-10-2018 IPR015396 Acyl-CoA dehydrogenase, C-termina, bacterial type GO:0003995|GO:0033539|GO:0055114 KEGG: 00071+1.3.8.8+1.3.8.7|KEGG: 00280+1.3.8.7|KEGG: 00410+1.3.8.7|KEGG: 00640+1.3.8.7|MetaCyc: PWY-7094|MetaCyc: PWY-7654 VAPA_1c15300 87b60a1d98f85d866f065d36df084c09 792 SUPERFAMILY SSF56645 101 334 4.32E-42 T 12-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 VAPA_1c15300 87b60a1d98f85d866f065d36df084c09 792 Gene3D G3DSA:1.10.540.10 103 215 3.7E-95 T 12-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 VAPA_1c53820 2fa49ae76bc3ddfad1fea30441c59ba7 365 Gene3D G3DSA:3.40.50.2000 156 333 4.7E-48 T 12-10-2018 VAPA_1c53820 2fa49ae76bc3ddfad1fea30441c59ba7 365 SUPERFAMILY SSF53756 14 346 1.64E-51 T 12-10-2018 VAPA_1c53820 2fa49ae76bc3ddfad1fea30441c59ba7 365 Gene3D G3DSA:3.40.50.2000 20 346 4.7E-48 T 12-10-2018 VAPA_1c53820 2fa49ae76bc3ddfad1fea30441c59ba7 365 Pfam PF00534 Glycosyl transferases group 1 176 322 6.1E-19 T 12-10-2018 IPR001296 Glycosyl transferase, family 1 VAPA_1c53820 2fa49ae76bc3ddfad1fea30441c59ba7 365 Pfam PF13477 Glycosyl transferase 4-like 4 133 2.1E-23 T 12-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 VAPA_1c48170 bf31e300f10e15a7b3938d560e69cf1b 190 Gene3D G3DSA:1.10.150.20 67 137 2.7E-26 T 12-10-2018 VAPA_1c48170 bf31e300f10e15a7b3938d560e69cf1b 190 SUPERFAMILY SSF47781 66 133 1.87E-21 T 12-10-2018 IPR010994 RuvA domain 2-like VAPA_1c48170 bf31e300f10e15a7b3938d560e69cf1b 190 Pfam PF07499 RuvA, C-terminal domain 145 188 8.9E-12 T 12-10-2018 IPR011114 Holliday junction DNA helicase RuvA, C-terminal GO:0005524|GO:0006281|GO:0006310|GO:0009378|GO:0009379 VAPA_1c48170 bf31e300f10e15a7b3938d560e69cf1b 190 SUPERFAMILY SSF46929 146 189 8.5E-9 T 12-10-2018 IPR036267 RuvA, C-terminal domain superfamily VAPA_1c48170 bf31e300f10e15a7b3938d560e69cf1b 190 Pfam PF01330 RuvA N terminal domain 1 62 8.9E-22 T 12-10-2018 IPR013849 DNA helicase, Holliday junction RuvA type, domain I, bacterial GO:0005524|GO:0006281|GO:0006310|GO:0009378 VAPA_1c48170 bf31e300f10e15a7b3938d560e69cf1b 190 Gene3D G3DSA:1.10.8.10 143 188 6.7E-6 T 12-10-2018 VAPA_1c48170 bf31e300f10e15a7b3938d560e69cf1b 190 TIGRFAM TIGR00084 ruvA: Holliday junction DNA helicase RuvA 1 188 5.8E-56 T 12-10-2018 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 VAPA_1c48170 bf31e300f10e15a7b3938d560e69cf1b 190 Gene3D G3DSA:2.40.50.140 1 65 6.6E-27 T 12-10-2018 VAPA_1c48170 bf31e300f10e15a7b3938d560e69cf1b 190 SUPERFAMILY SSF50249 1 63 5.31E-19 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold VAPA_1c48170 bf31e300f10e15a7b3938d560e69cf1b 190 Hamap MF_00031 Holliday junction ATP-dependent DNA helicase RuvA [ruvA]. 1 189 31.642 T 12-10-2018 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 VAPA_1c48170 bf31e300f10e15a7b3938d560e69cf1b 190 Pfam PF14520 Helix-hairpin-helix domain 72 129 3.9E-18 T 12-10-2018 VAPA_1c48170 bf31e300f10e15a7b3938d560e69cf1b 190 SMART SM00278 108 127 0.004 T 12-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 VAPA_1c48170 bf31e300f10e15a7b3938d560e69cf1b 190 SMART SM00278 73 92 4.1 T 12-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 VAPA_1c48180 b59b6b1f25216f2b0dcbc8ab78e95c56 313 Gene3D G3DSA:3.40.50.300 98 304 3.3E-71 T 12-10-2018 VAPA_1c48180 b59b6b1f25216f2b0dcbc8ab78e95c56 313 Pfam PF02562 PhoH-like protein 101 304 9.6E-93 T 12-10-2018 IPR003714 PhoH-like protein GO:0005524 VAPA_1c48180 b59b6b1f25216f2b0dcbc8ab78e95c56 313 SUPERFAMILY SSF52540 101 279 2.13E-38 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c40980 1df13c053fa5cc7d9c60ace73badcd43 304 SMART SM01130 5 293 1.2E-82 T 12-10-2018 IPR002220 DapA-like GO:0016829 VAPA_1c40980 1df13c053fa5cc7d9c60ace73badcd43 304 PRINTS PR00146 Dihydrodipicolinate synthase signature 39 60 2.4E-13 T 12-10-2018 IPR002220 DapA-like GO:0016829 VAPA_1c40980 1df13c053fa5cc7d9c60ace73badcd43 304 PRINTS PR00146 Dihydrodipicolinate synthase signature 132 149 2.4E-13 T 12-10-2018 IPR002220 DapA-like GO:0016829 VAPA_1c40980 1df13c053fa5cc7d9c60ace73badcd43 304 PRINTS PR00146 Dihydrodipicolinate synthase signature 75 93 2.4E-13 T 12-10-2018 IPR002220 DapA-like GO:0016829 VAPA_1c40980 1df13c053fa5cc7d9c60ace73badcd43 304 SUPERFAMILY SSF51569 5 291 5.65E-81 T 12-10-2018 VAPA_1c40980 1df13c053fa5cc7d9c60ace73badcd43 304 Gene3D G3DSA:3.20.20.70 3 299 2.3E-80 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 VAPA_1c40980 1df13c053fa5cc7d9c60ace73badcd43 304 Pfam PF00701 Dihydrodipicolinate synthetase family 7 292 2.0E-55 T 12-10-2018 IPR002220 DapA-like GO:0016829 VAPA_1c40980 1df13c053fa5cc7d9c60ace73badcd43 304 PIRSF PIRSF001365 1 303 1.1E-76 T 12-10-2018 IPR002220 DapA-like GO:0016829 VAPA_1c44920 3e83dc4a426f8e062c430e7f9de4e1be 243 ProSitePatterns PS01277 Ribonuclease PH signature. 120 133 - T 12-10-2018 IPR018336 Ribonuclease PH, conserved site VAPA_1c44920 3e83dc4a426f8e062c430e7f9de4e1be 243 SUPERFAMILY SSF54211 5 185 1.21E-44 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold VAPA_1c44920 3e83dc4a426f8e062c430e7f9de4e1be 243 Hamap MF_00564 Ribonuclease PH [rph]. 15 241 45.335 T 12-10-2018 IPR002381 Ribonuclease PH, bacterial-type GO:0000049|GO:0008033|GO:0009022 VAPA_1c44920 3e83dc4a426f8e062c430e7f9de4e1be 243 Pfam PF01138 3' exoribonuclease family, domain 1 14 144 3.3E-22 T 12-10-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 VAPA_1c44920 3e83dc4a426f8e062c430e7f9de4e1be 243 TIGRFAM TIGR01966 RNasePH: ribonuclease PH 6 240 1.3E-117 T 12-10-2018 IPR002381 Ribonuclease PH, bacterial-type GO:0000049|GO:0008033|GO:0009022 VAPA_1c44920 3e83dc4a426f8e062c430e7f9de4e1be 243 Gene3D G3DSA:3.30.230.70 14 241 4.5E-59 T 12-10-2018 IPR027408 PNPase/RNase PH domain superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 VAPA_1c44920 3e83dc4a426f8e062c430e7f9de4e1be 243 Pfam PF03725 3' exoribonuclease family, domain 2 163 227 5.4E-10 T 12-10-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 VAPA_1c44920 3e83dc4a426f8e062c430e7f9de4e1be 243 SUPERFAMILY SSF55666 156 238 3.8E-24 T 12-10-2018 IPR036345 Exoribonuclease, PH domain 2 superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 VAPA_1c13830 cbb8b0a7883b6190e9e1793067ee1b49 237 Gene3D G3DSA:3.40.50.12500 1 237 8.1E-70 T 12-10-2018 VAPA_1c13830 cbb8b0a7883b6190e9e1793067ee1b49 237 SUPERFAMILY SSF51366 49 225 9.54E-5 T 12-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 VAPA_1c13830 cbb8b0a7883b6190e9e1793067ee1b49 237 PIRSF PIRSF015736 2 237 1.4E-42 T 12-10-2018 IPR026286 Maleate isomerase/Arylmalonate decarboxylase VAPA_1c23470 3c412948e05504492f9d10eb9d5efe44 540 PIRSF PIRSF000331 8 496 3.7E-112 T 12-10-2018 IPR004925 HpaB/PvcC/4-BUDH VAPA_1c23470 3c412948e05504492f9d10eb9d5efe44 540 Pfam PF11794 4-hydroxyphenylacetate 3-hydroxylase N terminal 13 279 3.3E-88 T 12-10-2018 IPR024674 HpaB/PvcC/4-BUDH N-terminal VAPA_1c23470 3c412948e05504492f9d10eb9d5efe44 540 SUPERFAMILY SSF56645 10 280 3.66E-74 T 12-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 VAPA_1c23470 3c412948e05504492f9d10eb9d5efe44 540 Pfam PF03241 4-hydroxyphenylacetate 3-hydroxylase C terminal 288 488 1.0E-56 T 12-10-2018 IPR024719 HpaB/PvcC/4-BUDH C-terminal VAPA_1c23470 3c412948e05504492f9d10eb9d5efe44 540 Gene3D G3DSA:1.10.3140.10 9 151 2.8E-39 T 12-10-2018 VAPA_1c23470 3c412948e05504492f9d10eb9d5efe44 540 Gene3D G3DSA:1.20.140.10 284 490 1.5E-62 T 12-10-2018 VAPA_1c23470 3c412948e05504492f9d10eb9d5efe44 540 SUPERFAMILY SSF47203 271 489 5.23E-58 T 12-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 VAPA_1c23470 3c412948e05504492f9d10eb9d5efe44 540 Gene3D G3DSA:2.40.110.10 153 281 4.6E-42 T 12-10-2018 VAPA_1c38420 d8f7874b7502055654fcf345f55cbd35 702 SUPERFAMILY SSF56935 46 702 2.41E-84 T 12-10-2018 VAPA_1c38420 d8f7874b7502055654fcf345f55cbd35 702 Pfam PF00593 TonB dependent receptor 257 701 8.3E-35 T 12-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel VAPA_1c38420 d8f7874b7502055654fcf345f55cbd35 702 Gene3D G3DSA:2.40.170.20 172 702 4.3E-57 T 12-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily VAPA_1c38420 d8f7874b7502055654fcf345f55cbd35 702 Pfam PF07715 TonB-dependent Receptor Plug Domain 59 161 5.0E-16 T 12-10-2018 IPR012910 TonB-dependent receptor, plug domain VAPA_1c38420 d8f7874b7502055654fcf345f55cbd35 702 Gene3D G3DSA:2.170.130.10 55 171 1.2E-27 T 12-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily VAPA_1c45850 c262cc265402a8c93656678843e10486 496 Pfam PF07690 Major Facilitator Superfamily 18 413 6.0E-47 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 VAPA_1c45850 c262cc265402a8c93656678843e10486 496 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 14 423 1.1E-75 T 12-10-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0016021|GO:0022857|GO:0055085 VAPA_1c45850 c262cc265402a8c93656678843e10486 496 Gene3D G3DSA:1.20.1250.20 263 480 8.7E-20 T 12-10-2018 VAPA_1c45850 c262cc265402a8c93656678843e10486 496 Gene3D G3DSA:1.20.1720.10 14 224 3.5E-52 T 12-10-2018 VAPA_1c45850 c262cc265402a8c93656678843e10486 496 SUPERFAMILY SSF103473 7 466 9.42E-63 T 12-10-2018 IPR036259 MFS transporter superfamily VAPA_1c45850 c262cc265402a8c93656678843e10486 496 PRINTS PR01036 Tetracycline resistance protein TetB signature 139 163 4.0E-6 T 12-10-2018 VAPA_1c45850 c262cc265402a8c93656678843e10486 496 PRINTS PR01036 Tetracycline resistance protein TetB signature 77 99 4.0E-6 T 12-10-2018 VAPA_1c45850 c262cc265402a8c93656678843e10486 496 PRINTS PR01036 Tetracycline resistance protein TetB signature 17 41 4.0E-6 T 12-10-2018 VAPA_2c06820 c1cde17246721312906012cd1217cf20 327 Gene3D G3DSA:3.40.190.150 31 318 2.1E-98 T 12-10-2018 VAPA_2c06820 c1cde17246721312906012cd1217cf20 327 SUPERFAMILY SSF53850 114 291 4.78E-15 T 12-10-2018 VAPA_2c06820 c1cde17246721312906012cd1217cf20 327 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 49 324 7.0E-73 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_2c06820 c1cde17246721312906012cd1217cf20 327 PIRSF PIRSF017082 2 327 3.1E-68 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_2c06820 c1cde17246721312906012cd1217cf20 327 Gene3D G3DSA:3.40.190.10 130 253 2.1E-98 T 12-10-2018 VAPA_1c19240 b7b62bbb2faf10c79586542e02bbe21e 873 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 678 696 5.5E-42 T 12-10-2018 IPR001270 ClpA/B family GO:0005524 VAPA_1c19240 b7b62bbb2faf10c79586542e02bbe21e 873 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 649 667 5.5E-42 T 12-10-2018 IPR001270 ClpA/B family GO:0005524 VAPA_1c19240 b7b62bbb2faf10c79586542e02bbe21e 873 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 711 725 5.5E-42 T 12-10-2018 IPR001270 ClpA/B family GO:0005524 VAPA_1c19240 b7b62bbb2faf10c79586542e02bbe21e 873 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 604 622 5.5E-42 T 12-10-2018 IPR001270 ClpA/B family GO:0005524 VAPA_1c19240 b7b62bbb2faf10c79586542e02bbe21e 873 SUPERFAMILY SSF52540 157 546 1.17E-97 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c19240 b7b62bbb2faf10c79586542e02bbe21e 873 Gene3D G3DSA:1.10.1780.10 1 146 5.9E-27 T 12-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 VAPA_1c19240 b7b62bbb2faf10c79586542e02bbe21e 873 Gene3D G3DSA:3.40.50.300 147 340 1.3E-73 T 12-10-2018 VAPA_1c19240 b7b62bbb2faf10c79586542e02bbe21e 873 Gene3D G3DSA:3.40.50.300 341 547 9.7E-67 T 12-10-2018 VAPA_1c19240 b7b62bbb2faf10c79586542e02bbe21e 873 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 201 318 4.3E-13 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 VAPA_1c19240 b7b62bbb2faf10c79586542e02bbe21e 873 SMART SM00382 196 341 6.9E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c19240 b7b62bbb2faf10c79586542e02bbe21e 873 SMART SM00382 600 742 1.3E-9 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c19240 b7b62bbb2faf10c79586542e02bbe21e 873 Gene3D G3DSA:1.10.8.60 768 870 1.3E-23 T 12-10-2018 VAPA_1c19240 b7b62bbb2faf10c79586542e02bbe21e 873 Gene3D G3DSA:3.40.50.300 552 766 3.7E-87 T 12-10-2018 VAPA_1c19240 b7b62bbb2faf10c79586542e02bbe21e 873 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 768 848 1.0E-23 T 12-10-2018 IPR019489 Clp ATPase, C-terminal VAPA_1c19240 b7b62bbb2faf10c79586542e02bbe21e 873 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 292 304 - T 12-10-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 VAPA_1c19240 b7b62bbb2faf10c79586542e02bbe21e 873 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 634 652 - T 12-10-2018 IPR028299 ClpA/B, conserved site 2 VAPA_1c19240 b7b62bbb2faf10c79586542e02bbe21e 873 SUPERFAMILY SSF52540 549 842 4.47E-79 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c19240 b7b62bbb2faf10c79586542e02bbe21e 873 SUPERFAMILY SSF81923 4 154 2.26E-34 T 12-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 VAPA_1c19240 b7b62bbb2faf10c79586542e02bbe21e 873 TIGRFAM TIGR03346 chaperone_ClpB: ATP-dependent chaperone protein ClpB 6 851 0.0 T 12-10-2018 IPR017730 Chaperonin ClpB GO:0005737|GO:0009408|GO:0042026 VAPA_1c19240 b7b62bbb2faf10c79586542e02bbe21e 873 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 17 67 2.6E-11 T 12-10-2018 IPR004176 Clp, N-terminal VAPA_1c19240 b7b62bbb2faf10c79586542e02bbe21e 873 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 93 143 2.1E-8 T 12-10-2018 IPR004176 Clp, N-terminal VAPA_1c19240 b7b62bbb2faf10c79586542e02bbe21e 873 Pfam PF07724 AAA domain (Cdc48 subfamily) 599 761 1.8E-53 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 VAPA_1c19240 b7b62bbb2faf10c79586542e02bbe21e 873 SMART SM01086 768 861 5.1E-31 T 12-10-2018 IPR019489 Clp ATPase, C-terminal VAPA_1c43060 72050dd44e8905dd2c5cd864986193ae 218 Pfam PF04344 Chemotaxis phosphatase, CheZ 17 218 4.1E-73 T 12-10-2018 IPR007439 Chemotaxis phosphatase, CheZ GO:0003824|GO:0009288|GO:0050920 VAPA_1c43060 72050dd44e8905dd2c5cd864986193ae 218 PIRSF PIRSF002884 2 218 1.4E-76 T 12-10-2018 IPR007439 Chemotaxis phosphatase, CheZ GO:0003824|GO:0009288|GO:0050920 VAPA_1c43060 72050dd44e8905dd2c5cd864986193ae 218 Gene3D G3DSA:1.10.287.500 36 169 2.7E-50 T 12-10-2018 VAPA_1c43060 72050dd44e8905dd2c5cd864986193ae 218 SUPERFAMILY SSF75708 14 217 1.12E-59 T 12-10-2018 VAPA_1c45500 3d7df3a1fab21f0cd945d2843e208131 248 Gene3D G3DSA:3.40.50.2300 37 160 2.2E-20 T 12-10-2018 VAPA_1c45500 3d7df3a1fab21f0cd945d2843e208131 248 SMART SM00448 36 155 7.3E-15 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_1c45500 3d7df3a1fab21f0cd945d2843e208131 248 Pfam PF00072 Response regulator receiver domain 38 152 9.3E-16 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_1c45500 3d7df3a1fab21f0cd945d2843e208131 248 SMART SM00421 190 247 2.1E-20 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_1c45500 3d7df3a1fab21f0cd945d2843e208131 248 Pfam PF00196 Bacterial regulatory proteins, luxR family 192 245 1.0E-17 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_1c45500 3d7df3a1fab21f0cd945d2843e208131 248 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 207 223 1.2E-9 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_1c45500 3d7df3a1fab21f0cd945d2843e208131 248 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 223 235 1.2E-9 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_1c45500 3d7df3a1fab21f0cd945d2843e208131 248 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 193 207 1.2E-9 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_1c45500 3d7df3a1fab21f0cd945d2843e208131 248 Gene3D G3DSA:1.10.10.10 183 248 8.5E-19 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c45500 3d7df3a1fab21f0cd945d2843e208131 248 SUPERFAMILY SSF46894 186 245 7.82E-18 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 VAPA_1c45500 3d7df3a1fab21f0cd945d2843e208131 248 SUPERFAMILY SSF52172 38 158 6.12E-20 T 12-10-2018 IPR011006 CheY-like superfamily VAPA_1c25980 f56f831ba7d24479041b4a7552ea9110 109 Gene3D G3DSA:1.10.260.40 1 66 3.2E-7 T 12-10-2018 VAPA_1c25980 f56f831ba7d24479041b4a7552ea9110 109 SUPERFAMILY SSF47413 2 70 5.63E-9 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 VAPA_1c37840 f169928a06d6606a9c21c2f14ae397d4 325 PIRSF PIRSF017082 1 325 3.7E-84 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c37840 f169928a06d6606a9c21c2f14ae397d4 325 SUPERFAMILY SSF53850 112 285 1.05E-11 T 12-10-2018 VAPA_1c37840 f169928a06d6606a9c21c2f14ae397d4 325 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 49 320 1.7E-88 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c37840 f169928a06d6606a9c21c2f14ae397d4 325 Gene3D G3DSA:3.40.190.150 29 315 4.3E-113 T 12-10-2018 VAPA_1c37840 f169928a06d6606a9c21c2f14ae397d4 325 Gene3D G3DSA:3.40.190.10 127 250 4.3E-113 T 12-10-2018 VAPA_2c08730 17fb8b24f4d9a39b72eca2216b5c6beb 209 SUPERFAMILY SSF52172 6 127 4.02E-8 T 12-10-2018 IPR011006 CheY-like superfamily VAPA_2c08730 17fb8b24f4d9a39b72eca2216b5c6beb 209 SUPERFAMILY SSF46894 145 204 5.44E-17 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 VAPA_2c08730 17fb8b24f4d9a39b72eca2216b5c6beb 209 Gene3D G3DSA:3.40.50.12740 10 204 4.2E-30 T 12-10-2018 VAPA_2c08730 17fb8b24f4d9a39b72eca2216b5c6beb 209 SMART SM00421 141 198 1.5E-17 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_2c08730 17fb8b24f4d9a39b72eca2216b5c6beb 209 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 144 158 7.8E-12 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_2c08730 17fb8b24f4d9a39b72eca2216b5c6beb 209 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 174 186 7.8E-12 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_2c08730 17fb8b24f4d9a39b72eca2216b5c6beb 209 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 158 174 7.8E-12 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_2c08730 17fb8b24f4d9a39b72eca2216b5c6beb 209 Pfam PF00196 Bacterial regulatory proteins, luxR family 145 196 7.2E-16 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_2c08730 17fb8b24f4d9a39b72eca2216b5c6beb 209 ProSitePatterns PS00622 LuxR-type HTH domain signature. 158 185 - T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_1c18220 b7f432f6ce5dcd7143a332984379da45 526 Gene3D G3DSA:3.40.190.10 42 294 2.0E-72 T 12-10-2018 VAPA_1c18220 b7f432f6ce5dcd7143a332984379da45 526 SUPERFAMILY SSF161098 319 500 3.27E-34 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c18220 b7f432f6ce5dcd7143a332984379da45 526 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 340 509 4.3E-20 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 VAPA_1c18220 b7f432f6ce5dcd7143a332984379da45 526 SUPERFAMILY SSF53850 39 296 2.67E-53 T 12-10-2018 VAPA_1c18220 b7f432f6ce5dcd7143a332984379da45 526 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 40 295 1.8E-53 T 12-10-2018 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0022857|GO:0043190|GO:0055085 VAPA_1c18220 b7f432f6ce5dcd7143a332984379da45 526 Gene3D G3DSA:1.10.3720.10 320 514 9.1E-26 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c18220 b7f432f6ce5dcd7143a332984379da45 526 Gene3D G3DSA:3.40.190.120 138 239 2.0E-72 T 12-10-2018 VAPA_1c28550 f973b2da687b51dc746a967e33498ac5 594 Pfam PF00005 ABC transporter 364 512 7.8E-33 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c28550 f973b2da687b51dc746a967e33498ac5 594 SMART SM00382 373 558 5.6E-21 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c28550 f973b2da687b51dc746a967e33498ac5 594 ProSitePatterns PS00211 ABC transporters family signature. 484 498 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_1c28550 f973b2da687b51dc746a967e33498ac5 594 Gene3D G3DSA:3.40.50.300 337 586 5.6E-88 T 12-10-2018 VAPA_1c28550 f973b2da687b51dc746a967e33498ac5 594 SUPERFAMILY SSF90123 20 332 2.35E-55 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 VAPA_1c28550 f973b2da687b51dc746a967e33498ac5 594 Pfam PF00664 ABC transporter transmembrane region 34 301 9.6E-37 T 12-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 VAPA_1c28550 f973b2da687b51dc746a967e33498ac5 594 TIGRFAM TIGR02203 MsbA_lipidA: lipid A export permease/ATP-binding protein MsbA 20 583 7.3E-201 T 12-10-2018 IPR011917 ABC transporter, lipid A export, MsbA GO:0005524|GO:0016021|GO:0034040 VAPA_1c28550 f973b2da687b51dc746a967e33498ac5 594 Gene3D G3DSA:1.20.1560.10 4 332 6.2E-57 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 VAPA_1c28550 f973b2da687b51dc746a967e33498ac5 594 SUPERFAMILY SSF52540 337 580 2.93E-86 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c35450 e34cdd1b12ad95e80e46d4037f03ad30 174 Gene3D G3DSA:2.40.10.330 69 125 3.7E-34 T 12-10-2018 VAPA_1c35450 e34cdd1b12ad95e80e46d4037f03ad30 174 SUPERFAMILY SSF54534 4 144 2.75E-19 T 12-10-2018 VAPA_1c35450 e34cdd1b12ad95e80e46d4037f03ad30 174 Gene3D G3DSA:3.10.50.40 3 155 3.7E-34 T 12-10-2018 VAPA_1c05410 417e829c7a81e81cee1a7dc025cb089f 561 Gene3D G3DSA:3.40.50.620 120 438 2.2E-150 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold VAPA_1c05410 417e829c7a81e81cee1a7dc025cb089f 561 Pfam PF00750 tRNA synthetases class I (R) 101 409 3.6E-21 T 12-10-2018 IPR035684 Arginyl-tRNA synthetase, catalytic core domain KEGG: 00970+6.1.1.19 VAPA_1c05410 417e829c7a81e81cee1a7dc025cb089f 561 Gene3D G3DSA:1.10.730.10 439 561 2.2E-150 T 12-10-2018 VAPA_1c05410 417e829c7a81e81cee1a7dc025cb089f 561 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 130 139 - T 12-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 VAPA_1c05410 417e829c7a81e81cee1a7dc025cb089f 561 Gene3D G3DSA:3.30.1360.70 1 109 2.0E-21 T 12-10-2018 IPR036695 Arginyl tRNA synthetase N-terminal domain superfamily GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 VAPA_1c05410 417e829c7a81e81cee1a7dc025cb089f 561 SUPERFAMILY SSF47323 439 561 4.77E-36 T 12-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 VAPA_1c05410 417e829c7a81e81cee1a7dc025cb089f 561 Pfam PF03485 Arginyl tRNA synthetase N terminal domain 7 92 1.3E-19 T 12-10-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 VAPA_1c05410 417e829c7a81e81cee1a7dc025cb089f 561 SMART SM00836 444 561 6.7E-51 T 12-10-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 VAPA_1c05410 417e829c7a81e81cee1a7dc025cb089f 561 PRINTS PR01038 Arginyl-tRNA synthetase signature 311 332 1.7E-21 T 12-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 VAPA_1c05410 417e829c7a81e81cee1a7dc025cb089f 561 PRINTS PR01038 Arginyl-tRNA synthetase signature 120 135 1.7E-21 T 12-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 VAPA_1c05410 417e829c7a81e81cee1a7dc025cb089f 561 PRINTS PR01038 Arginyl-tRNA synthetase signature 135 151 1.7E-21 T 12-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 VAPA_1c05410 417e829c7a81e81cee1a7dc025cb089f 561 PRINTS PR01038 Arginyl-tRNA synthetase signature 159 172 1.7E-21 T 12-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 VAPA_1c05410 417e829c7a81e81cee1a7dc025cb089f 561 SUPERFAMILY SSF52374 115 454 8.19E-83 T 12-10-2018 VAPA_1c05410 417e829c7a81e81cee1a7dc025cb089f 561 Hamap MF_00123 Arginine--tRNA ligase [argS]. 6 561 24.049 T 12-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 VAPA_1c05410 417e829c7a81e81cee1a7dc025cb089f 561 SUPERFAMILY SSF55190 7 105 1.83E-18 T 12-10-2018 IPR036695 Arginyl tRNA synthetase N-terminal domain superfamily GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 VAPA_1c05410 417e829c7a81e81cee1a7dc025cb089f 561 SMART SM01016 6 92 1.5E-30 T 12-10-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 VAPA_1c05410 417e829c7a81e81cee1a7dc025cb089f 561 TIGRFAM TIGR00456 argS: arginine--tRNA ligase 6 561 1.3E-117 T 12-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 VAPA_1c05410 417e829c7a81e81cee1a7dc025cb089f 561 Pfam PF05746 DALR anticodon binding domain 444 561 1.3E-33 T 12-10-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 VAPA_1c26540 72a86dd147de1483405f29e3cf104f89 390 Gene3D G3DSA:1.20.1250.20 218 384 1.9E-12 T 12-10-2018 VAPA_1c26540 72a86dd147de1483405f29e3cf104f89 390 Pfam PF07690 Major Facilitator Superfamily 25 200 7.7E-10 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 VAPA_1c26540 72a86dd147de1483405f29e3cf104f89 390 Pfam PF07690 Major Facilitator Superfamily 224 372 7.1E-13 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 VAPA_1c26540 72a86dd147de1483405f29e3cf104f89 390 Gene3D G3DSA:1.20.1250.20 20 192 9.9E-11 T 12-10-2018 VAPA_1c26540 72a86dd147de1483405f29e3cf104f89 390 SUPERFAMILY SSF103473 26 376 1.96E-30 T 12-10-2018 IPR036259 MFS transporter superfamily VAPA_1c21590 6fba2d37c301c5474f123dddc469d214 283 Gene3D G3DSA:3.30.200.20 16 126 3.8E-5 T 12-10-2018 VAPA_1c21590 6fba2d37c301c5474f123dddc469d214 283 SMART SM00090 7 234 9.0E-13 T 12-10-2018 IPR000687 RIO kinase GO:0004674|GO:0005524 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1|Reactome: R-HSA-6791226 VAPA_1c21590 6fba2d37c301c5474f123dddc469d214 283 SUPERFAMILY SSF56112 19 225 1.35E-18 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily VAPA_1c21590 6fba2d37c301c5474f123dddc469d214 283 Gene3D G3DSA:1.10.510.10 139 220 2.1E-18 T 12-10-2018 VAPA_1c21590 6fba2d37c301c5474f123dddc469d214 283 Pfam PF01163 RIO1 family 31 219 3.0E-42 T 12-10-2018 VAPA_1c21590 6fba2d37c301c5474f123dddc469d214 283 ProSitePatterns PS01245 RIO1/ZK632.3/MJ0444 family signature. 164 175 - T 12-10-2018 IPR018935 RIO kinase, conserved site GO:0004674|GO:0005524 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1|Reactome: R-HSA-6791226 VAPA_1c17840 3c8edb23bd671dd7c78e7f26070db1be 202 SMART SM00474 31 202 3.0E-9 T 12-10-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 VAPA_1c17840 3c8edb23bd671dd7c78e7f26070db1be 202 SUPERFAMILY SSF53098 25 199 5.88E-34 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily VAPA_1c17840 3c8edb23bd671dd7c78e7f26070db1be 202 Pfam PF01612 3'-5' exonuclease 32 199 2.5E-20 T 12-10-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 VAPA_1c17840 3c8edb23bd671dd7c78e7f26070db1be 202 Gene3D G3DSA:3.30.420.10 27 200 2.1E-36 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 VAPA_1c30610 a2dc65c9b21e5138647eaccb90cfc919 326 Pfam PF02653 Branched-chain amino acid transport system / permease component 35 313 3.6E-34 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 VAPA_1c47280 e286b006a5991ae997a88dcadcb5bd88 1663 Gene3D G3DSA:3.40.50.300 440 620 1.5E-46 T 12-10-2018 VAPA_1c47280 e286b006a5991ae997a88dcadcb5bd88 1663 Gene3D G3DSA:3.30.420.10 2 99 2.3E-6 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 VAPA_1c47280 e286b006a5991ae997a88dcadcb5bd88 1663 Gene3D G3DSA:1.10.486.10 1395 1450 7.4E-21 T 12-10-2018 VAPA_1c47280 e286b006a5991ae997a88dcadcb5bd88 1663 SUPERFAMILY SSF53098 4 97 6.0E-7 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily VAPA_1c47280 e286b006a5991ae997a88dcadcb5bd88 1663 Gene3D G3DSA:3.40.50.300 1451 1515 7.4E-21 T 12-10-2018 VAPA_1c47280 e286b006a5991ae997a88dcadcb5bd88 1663 Pfam PF13361 UvrD-like helicase C-terminal domain 1449 1512 5.0E-14 T 12-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 VAPA_1c47280 e286b006a5991ae997a88dcadcb5bd88 1663 Gene3D G3DSA:3.40.50.300 1248 1368 1.1E-9 T 12-10-2018 VAPA_1c47280 e286b006a5991ae997a88dcadcb5bd88 1663 SMART SM00487 242 448 6.8E-23 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain VAPA_1c47280 e286b006a5991ae997a88dcadcb5bd88 1663 Gene3D G3DSA:3.40.50.300 217 431 1.3E-61 T 12-10-2018 VAPA_1c47280 e286b006a5991ae997a88dcadcb5bd88 1663 Gene3D G3DSA:3.40.50.300 1030 1245 2.6E-47 T 12-10-2018 VAPA_1c47280 e286b006a5991ae997a88dcadcb5bd88 1663 Pfam PF00270 DEAD/DEAH box helicase 249 415 2.8E-19 T 12-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 VAPA_1c47280 e286b006a5991ae997a88dcadcb5bd88 1663 Pfam PF00271 Helicase conserved C-terminal domain 454 564 2.3E-20 T 12-10-2018 IPR001650 Helicase, C-terminal VAPA_1c47280 e286b006a5991ae997a88dcadcb5bd88 1663 Pfam PF13245 AAA domain 1046 1225 1.0E-31 T 12-10-2018 VAPA_1c47280 e286b006a5991ae997a88dcadcb5bd88 1663 SUPERFAMILY SSF52540 1039 1515 1.86E-83 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c47280 e286b006a5991ae997a88dcadcb5bd88 1663 Pfam PF13361 UvrD-like helicase C-terminal domain 1245 1351 5.8E-6 T 12-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 VAPA_1c47280 e286b006a5991ae997a88dcadcb5bd88 1663 SUPERFAMILY SSF52540 289 583 9.96E-57 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c47280 e286b006a5991ae997a88dcadcb5bd88 1663 TIGRFAM TIGR00614 recQ_fam: ATP-dependent DNA helicase, RecQ family 249 585 9.4E-93 T 12-10-2018 IPR004589 DNA helicase, ATP-dependent, RecQ type GO:0006310|GO:0008026 VAPA_1c47280 e286b006a5991ae997a88dcadcb5bd88 1663 SMART SM00490 484 565 7.5E-26 T 12-10-2018 IPR001650 Helicase, C-terminal VAPA_1c53770 a7e09a5df808da8c758a5dab90b322b1 85 Gene3D G3DSA:3.30.1150.10 16 83 8.9E-10 T 12-10-2018 VAPA_1c53770 a7e09a5df808da8c758a5dab90b322b1 85 Pfam PF03544 Gram-negative bacterial TonB protein C-terminal 24 82 6.1E-6 T 12-10-2018 IPR037682 TonB, C-terminal GO:0055085 VAPA_1c53770 a7e09a5df808da8c758a5dab90b322b1 85 SUPERFAMILY SSF74653 23 81 2.55E-8 T 12-10-2018 VAPA_1c26830 4a0bab493158e15c3799b53f5afc5be4 358 Pfam PF01734 Patatin-like phospholipase 55 245 5.1E-6 T 12-10-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 VAPA_1c26830 4a0bab493158e15c3799b53f5afc5be4 358 SUPERFAMILY SSF52151 53 338 7.85E-14 T 12-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase VAPA_1c20350 6b5c92b766fd0ba1117ecc1c55f78d2b 328 Gene3D G3DSA:3.40.190.10 126 249 1.5E-83 T 12-10-2018 VAPA_1c20350 6b5c92b766fd0ba1117ecc1c55f78d2b 328 Gene3D G3DSA:3.40.190.150 29 313 1.5E-83 T 12-10-2018 VAPA_1c20350 6b5c92b766fd0ba1117ecc1c55f78d2b 328 PIRSF PIRSF017082 1 326 1.1E-61 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c20350 6b5c92b766fd0ba1117ecc1c55f78d2b 328 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 49 322 1.7E-52 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c20350 6b5c92b766fd0ba1117ecc1c55f78d2b 328 SUPERFAMILY SSF53850 115 285 5.97E-5 T 12-10-2018 VAPA_2c01720 2ea9c68c8150a428ae1c34db50ddb23b 332 Gene3D G3DSA:3.40.50.720 104 292 8.7E-80 T 12-10-2018 VAPA_2c01720 2ea9c68c8150a428ae1c34db50ddb23b 332 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 225 241 - T 12-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site VAPA_2c01720 2ea9c68c8150a428ae1c34db50ddb23b 332 SUPERFAMILY SSF51735 109 286 1.66E-45 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_2c01720 2ea9c68c8150a428ae1c34db50ddb23b 332 Gene3D G3DSA:3.40.50.720 17 313 8.7E-80 T 12-10-2018 VAPA_2c01720 2ea9c68c8150a428ae1c34db50ddb23b 332 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 19 318 1.2E-15 T 12-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 VAPA_2c01720 2ea9c68c8150a428ae1c34db50ddb23b 332 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 115 286 7.7E-50 T 12-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 VAPA_2c01720 2ea9c68c8150a428ae1c34db50ddb23b 332 SUPERFAMILY SSF52283 19 129 2.76E-17 T 12-10-2018 VAPA_2c01610 bb7e7b41089515d8d65e9969e23669e8 250 SUPERFAMILY SSF51735 3 250 4.38E-72 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_2c01610 bb7e7b41089515d8d65e9969e23669e8 250 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 8 249 9.0E-58 T 12-10-2018 VAPA_2c01610 bb7e7b41089515d8d65e9969e23669e8 250 Gene3D G3DSA:3.40.50.720 2 249 5.0E-74 T 12-10-2018 VAPA_2c01610 bb7e7b41089515d8d65e9969e23669e8 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 4.7E-6 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c01610 bb7e7b41089515d8d65e9969e23669e8 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 4.7E-6 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c01610 bb7e7b41089515d8d65e9969e23669e8 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 4.7E-6 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c01610 bb7e7b41089515d8d65e9969e23669e8 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 1.2E-31 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c01610 bb7e7b41089515d8d65e9969e23669e8 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 1.2E-31 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c01610 bb7e7b41089515d8d65e9969e23669e8 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 1.2E-31 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c01610 bb7e7b41089515d8d65e9969e23669e8 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 1.2E-31 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c01610 bb7e7b41089515d8d65e9969e23669e8 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 1.2E-31 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c01610 bb7e7b41089515d8d65e9969e23669e8 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 212 232 1.2E-31 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c23560 a9e6dc0e5dee17ecfe8bde9166054c25 255 SUPERFAMILY SSF81606 7 249 4.71E-47 T 12-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 VAPA_1c23560 a9e6dc0e5dee17ecfe8bde9166054c25 255 Gene3D G3DSA:3.60.40.10 1 251 1.7E-46 T 12-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 VAPA_1c23560 a9e6dc0e5dee17ecfe8bde9166054c25 255 Pfam PF13672 Protein phosphatase 2C 21 207 1.5E-9 T 12-10-2018 VAPA_1c23560 a9e6dc0e5dee17ecfe8bde9166054c25 255 SMART SM00332 2 247 2.7E-5 T 12-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 VAPA_1c23560 a9e6dc0e5dee17ecfe8bde9166054c25 255 SMART SM00331 23 249 3.6E-18 T 12-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 VAPA_2c03340 35762327cceab17ded1baefe25956bfa 163 Pfam PF00582 Universal stress protein family 1 144 1.2E-30 T 12-10-2018 IPR006016 UspA VAPA_2c03340 35762327cceab17ded1baefe25956bfa 163 SUPERFAMILY SSF52402 1 144 4.6E-35 T 12-10-2018 VAPA_2c03340 35762327cceab17ded1baefe25956bfa 163 Gene3D G3DSA:3.40.50.620 1 145 1.6E-36 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold VAPA_2c03340 35762327cceab17ded1baefe25956bfa 163 PRINTS PR01438 Universal stress protein signature 104 116 1.6E-19 T 12-10-2018 IPR006015 Universal stress protein A VAPA_2c03340 35762327cceab17ded1baefe25956bfa 163 PRINTS PR01438 Universal stress protein signature 2 20 1.6E-19 T 12-10-2018 IPR006015 Universal stress protein A VAPA_2c03340 35762327cceab17ded1baefe25956bfa 163 PRINTS PR01438 Universal stress protein signature 122 144 1.6E-19 T 12-10-2018 IPR006015 Universal stress protein A VAPA_1c25870 2998e9ad31f267aa0e213b85c8c1a953 215 Pfam PF02525 Flavodoxin-like fold 1 200 1.7E-47 T 12-10-2018 IPR003680 Flavodoxin-like fold VAPA_1c25870 2998e9ad31f267aa0e213b85c8c1a953 215 Gene3D G3DSA:3.40.50.360 1 203 3.9E-58 T 12-10-2018 IPR029039 Flavoprotein-like superfamily VAPA_1c25870 2998e9ad31f267aa0e213b85c8c1a953 215 SUPERFAMILY SSF52218 1 202 9.72E-56 T 12-10-2018 IPR029039 Flavoprotein-like superfamily VAPA_1c25870 2998e9ad31f267aa0e213b85c8c1a953 215 Hamap MF_01216 FMN-dependent NADH-azoreductase [azoR]. 1 202 30.908 T 12-10-2018 IPR023048 NADH-azoreductase, FMN-dependent GO:0016661|GO:0055114 VAPA_1c52130 77a9db4f4755bc9a764a639817f2a533 258 SMART SM00382 35 225 1.2E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c52130 77a9db4f4755bc9a764a639817f2a533 258 Gene3D G3DSA:3.40.50.300 1 245 4.4E-54 T 12-10-2018 VAPA_1c52130 77a9db4f4755bc9a764a639817f2a533 258 ProSitePatterns PS00211 ABC transporters family signature. 149 163 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_1c52130 77a9db4f4755bc9a764a639817f2a533 258 Pfam PF00005 ABC transporter 27 177 7.2E-27 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c52130 77a9db4f4755bc9a764a639817f2a533 258 SUPERFAMILY SSF52540 6 230 1.23E-54 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_2c08600 55029f4e88faa9ec973a4c276e15c158 114 Gene3D G3DSA:4.10.490.10 39 113 1.6E-23 T 12-10-2018 IPR036369 High potential iron-sulphur protein superfamily GO:0009055|GO:0019646 VAPA_2c08600 55029f4e88faa9ec973a4c276e15c158 114 SUPERFAMILY SSF57652 36 112 1.44E-23 T 12-10-2018 IPR036369 High potential iron-sulphur protein superfamily GO:0009055|GO:0019646 VAPA_2c08600 55029f4e88faa9ec973a4c276e15c158 114 Pfam PF01355 High potential iron-sulfur protein 45 110 3.5E-21 T 12-10-2018 IPR000170 High potential iron-sulphur protein GO:0009055|GO:0019646 VAPA_1c49820 b55ce3ccf20a19e5ebf9c4053f4934b6 302 Gene3D G3DSA:1.10.1040.10 179 302 7.9E-40 T 12-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 VAPA_1c49820 b55ce3ccf20a19e5ebf9c4053f4934b6 302 PIRSF PIRSF000103 10 302 9.4E-74 T 12-10-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 VAPA_1c49820 b55ce3ccf20a19e5ebf9c4053f4934b6 302 SUPERFAMILY SSF51735 16 178 9.98E-53 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c49820 b55ce3ccf20a19e5ebf9c4053f4934b6 302 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 181 298 4.3E-35 T 12-10-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 VAPA_1c49820 b55ce3ccf20a19e5ebf9c4053f4934b6 302 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 17 176 2.3E-50 T 12-10-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 VAPA_1c49820 b55ce3ccf20a19e5ebf9c4053f4934b6 302 Gene3D G3DSA:3.40.50.720 4 178 1.1E-54 T 12-10-2018 VAPA_1c49820 b55ce3ccf20a19e5ebf9c4053f4934b6 302 ProSitePatterns PS00895 3-hydroxyisobutyrate dehydrogenase signature. 19 32 - T 12-10-2018 IPR002204 3-hydroxyisobutyrate dehydrogenase-related, conserved site GO:0016491|GO:0055114 Reactome: R-HSA-70895 VAPA_1c49820 b55ce3ccf20a19e5ebf9c4053f4934b6 302 SUPERFAMILY SSF48179 180 300 6.12E-40 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 VAPA_1c36710 661c1c1ddd7d3f0a517d7b8e94d7e98c 1067 SUPERFAMILY SSF82714 193 274 3.01E-17 T 12-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains VAPA_1c36710 661c1c1ddd7d3f0a517d7b8e94d7e98c 1067 Gene3D G3DSA:3.30.70.1430 570 675 1.4E-302 T 12-10-2018 VAPA_1c36710 661c1c1ddd7d3f0a517d7b8e94d7e98c 1067 TIGRFAM TIGR00914 2A0601: heavy metal efflux pump, CzcA family 1 1050 0.0 T 12-10-2018 IPR004763 Cation efflux system CzcA/CusA/SilA/NccA/HelA/CnrA GO:0006812|GO:0008324|GO:0016021 VAPA_1c36710 661c1c1ddd7d3f0a517d7b8e94d7e98c 1067 Gene3D G3DSA:3.30.70.1320 135 333 1.4E-302 T 12-10-2018 VAPA_1c36710 661c1c1ddd7d3f0a517d7b8e94d7e98c 1067 SUPERFAMILY SSF82693 42 128 8.55E-23 T 12-10-2018 VAPA_1c36710 661c1c1ddd7d3f0a517d7b8e94d7e98c 1067 PRINTS PR00702 Acriflavin resistance protein family signature 339 362 8.8E-23 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 VAPA_1c36710 661c1c1ddd7d3f0a517d7b8e94d7e98c 1067 PRINTS PR00702 Acriflavin resistance protein family signature 366 387 8.8E-23 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 VAPA_1c36710 661c1c1ddd7d3f0a517d7b8e94d7e98c 1067 PRINTS PR00702 Acriflavin resistance protein family signature 480 503 8.8E-23 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 VAPA_1c36710 661c1c1ddd7d3f0a517d7b8e94d7e98c 1067 PRINTS PR00702 Acriflavin resistance protein family signature 12 36 8.8E-23 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 VAPA_1c36710 661c1c1ddd7d3f0a517d7b8e94d7e98c 1067 PRINTS PR00702 Acriflavin resistance protein family signature 553 570 8.8E-23 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 VAPA_1c36710 661c1c1ddd7d3f0a517d7b8e94d7e98c 1067 PRINTS PR00702 Acriflavin resistance protein family signature 40 58 8.8E-23 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 VAPA_1c36710 661c1c1ddd7d3f0a517d7b8e94d7e98c 1067 Gene3D G3DSA:1.20.1640.10 16 516 1.4E-302 T 12-10-2018 VAPA_1c36710 661c1c1ddd7d3f0a517d7b8e94d7e98c 1067 Gene3D G3DSA:3.30.70.1430 42 831 1.4E-302 T 12-10-2018 VAPA_1c36710 661c1c1ddd7d3f0a517d7b8e94d7e98c 1067 SUPERFAMILY SSF82693 577 668 2.56E-6 T 12-10-2018 VAPA_1c36710 661c1c1ddd7d3f0a517d7b8e94d7e98c 1067 Gene3D G3DSA:3.30.2090.10 189 280 1.4E-302 T 12-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains VAPA_1c36710 661c1c1ddd7d3f0a517d7b8e94d7e98c 1067 SUPERFAMILY SSF82714 726 818 4.84E-17 T 12-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains VAPA_1c36710 661c1c1ddd7d3f0a517d7b8e94d7e98c 1067 SUPERFAMILY SSF82866 299 506 3.14E-35 T 12-10-2018 VAPA_1c36710 661c1c1ddd7d3f0a517d7b8e94d7e98c 1067 SUPERFAMILY SSF82866 817 1042 9.68E-55 T 12-10-2018 VAPA_1c36710 661c1c1ddd7d3f0a517d7b8e94d7e98c 1067 Gene3D G3DSA:1.20.1640.10 517 1035 1.4E-302 T 12-10-2018 VAPA_1c36710 661c1c1ddd7d3f0a517d7b8e94d7e98c 1067 Gene3D G3DSA:3.30.70.1440 676 880 1.4E-302 T 12-10-2018 VAPA_1c36710 661c1c1ddd7d3f0a517d7b8e94d7e98c 1067 Pfam PF00873 AcrB/AcrD/AcrF family 5 1038 0.0 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 VAPA_1c36710 661c1c1ddd7d3f0a517d7b8e94d7e98c 1067 SUPERFAMILY SSF82693 155 333 4.19E-20 T 12-10-2018 VAPA_1c36710 661c1c1ddd7d3f0a517d7b8e94d7e98c 1067 Gene3D G3DSA:3.30.2090.10 727 823 1.4E-302 T 12-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains VAPA_2c04700 826abd345a5425b43cf6f30dadf41100 281 PRINTS PR01438 Universal stress protein signature 259 281 2.0E-9 T 12-10-2018 IPR006015 Universal stress protein A VAPA_2c04700 826abd345a5425b43cf6f30dadf41100 281 PRINTS PR01438 Universal stress protein signature 241 253 2.0E-9 T 12-10-2018 IPR006015 Universal stress protein A VAPA_2c04700 826abd345a5425b43cf6f30dadf41100 281 PRINTS PR01438 Universal stress protein signature 7 25 2.0E-9 T 12-10-2018 IPR006015 Universal stress protein A VAPA_2c04700 826abd345a5425b43cf6f30dadf41100 281 Gene3D G3DSA:3.40.50.12370 9 281 2.3E-34 T 12-10-2018 VAPA_2c04700 826abd345a5425b43cf6f30dadf41100 281 SUPERFAMILY SSF52402 4 149 7.45E-11 T 12-10-2018 VAPA_2c04700 826abd345a5425b43cf6f30dadf41100 281 Pfam PF00582 Universal stress protein family 8 149 1.2E-6 T 12-10-2018 IPR006016 UspA VAPA_2c04700 826abd345a5425b43cf6f30dadf41100 281 Pfam PF00582 Universal stress protein family 161 279 3.0E-9 T 12-10-2018 IPR006016 UspA VAPA_2c04700 826abd345a5425b43cf6f30dadf41100 281 SUPERFAMILY SSF52402 158 280 1.67E-19 T 12-10-2018 VAPA_1c42230 852222a1440531aebce5dcb56ed6a364 115 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 23 85 3.3E-14 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c42230 852222a1440531aebce5dcb56ed6a364 115 SUPERFAMILY SSF46785 4 104 2.6E-27 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c42230 852222a1440531aebce5dcb56ed6a364 115 Gene3D G3DSA:1.10.10.10 1 115 4.8E-37 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c50020 5f1ab4e516972499825becf62105eb04 1054 Gene3D G3DSA:3.30.70.1440 668 864 0.0 T 12-10-2018 VAPA_1c50020 5f1ab4e516972499825becf62105eb04 1054 SUPERFAMILY SSF82866 805 1025 1.02E-40 T 12-10-2018 VAPA_1c50020 5f1ab4e516972499825becf62105eb04 1054 PRINTS PR00702 Acriflavin resistance protein family signature 470 493 1.9E-102 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 VAPA_1c50020 5f1ab4e516972499825becf62105eb04 1054 PRINTS PR00702 Acriflavin resistance protein family signature 36 54 1.9E-102 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 VAPA_1c50020 5f1ab4e516972499825becf62105eb04 1054 PRINTS PR00702 Acriflavin resistance protein family signature 620 634 1.9E-102 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 VAPA_1c50020 5f1ab4e516972499825becf62105eb04 1054 PRINTS PR00702 Acriflavin resistance protein family signature 391 415 1.9E-102 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 VAPA_1c50020 5f1ab4e516972499825becf62105eb04 1054 PRINTS PR00702 Acriflavin resistance protein family signature 445 468 1.9E-102 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 VAPA_1c50020 5f1ab4e516972499825becf62105eb04 1054 PRINTS PR00702 Acriflavin resistance protein family signature 8 32 1.9E-102 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 VAPA_1c50020 5f1ab4e516972499825becf62105eb04 1054 PRINTS PR00702 Acriflavin resistance protein family signature 553 570 1.9E-102 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 VAPA_1c50020 5f1ab4e516972499825becf62105eb04 1054 PRINTS PR00702 Acriflavin resistance protein family signature 336 359 1.9E-102 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 VAPA_1c50020 5f1ab4e516972499825becf62105eb04 1054 PRINTS PR00702 Acriflavin resistance protein family signature 363 384 1.9E-102 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 VAPA_1c50020 5f1ab4e516972499825becf62105eb04 1054 SUPERFAMILY SSF82866 298 497 2.09E-49 T 12-10-2018 VAPA_1c50020 5f1ab4e516972499825becf62105eb04 1054 Gene3D G3DSA:3.30.70.1430 568 667 0.0 T 12-10-2018 VAPA_1c50020 5f1ab4e516972499825becf62105eb04 1054 SUPERFAMILY SSF82693 38 131 3.92E-24 T 12-10-2018 VAPA_1c50020 5f1ab4e516972499825becf62105eb04 1054 Gene3D G3DSA:1.20.1640.10 8 513 0.0 T 12-10-2018 VAPA_1c50020 5f1ab4e516972499825becf62105eb04 1054 Gene3D G3DSA:3.30.2090.10 179 275 0.0 T 12-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains VAPA_1c50020 5f1ab4e516972499825becf62105eb04 1054 TIGRFAM TIGR00915 2A0602: RND transporter, hydrophobe/amphiphile efflux-1 (HAE1) family 1 1043 0.0 T 12-10-2018 IPR004764 Hydrophobe/amphiphile efflux-1 HAE1 GO:0006855|GO:0015562|GO:0016021 VAPA_1c50020 5f1ab4e516972499825becf62105eb04 1054 Gene3D G3DSA:3.30.70.1430 38 816 0.0 T 12-10-2018 VAPA_1c50020 5f1ab4e516972499825becf62105eb04 1054 Gene3D G3DSA:1.20.1640.10 514 1021 0.0 T 12-10-2018 VAPA_1c50020 5f1ab4e516972499825becf62105eb04 1054 SUPERFAMILY SSF82714 183 271 4.97E-23 T 12-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains VAPA_1c50020 5f1ab4e516972499825becf62105eb04 1054 Gene3D G3DSA:3.30.70.1320 133 332 0.0 T 12-10-2018 VAPA_1c50020 5f1ab4e516972499825becf62105eb04 1054 Pfam PF00873 AcrB/AcrD/AcrF family 1 1025 0.0 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 VAPA_1c50020 5f1ab4e516972499825becf62105eb04 1054 SUPERFAMILY SSF82693 566 669 3.4E-32 T 12-10-2018 VAPA_1c50020 5f1ab4e516972499825becf62105eb04 1054 Gene3D G3DSA:3.30.2090.10 720 808 0.0 T 12-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains VAPA_1c50020 5f1ab4e516972499825becf62105eb04 1054 SUPERFAMILY SSF82714 721 806 1.01E-19 T 12-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains VAPA_1c50020 5f1ab4e516972499825becf62105eb04 1054 SUPERFAMILY SSF82693 135 330 2.27E-26 T 12-10-2018 VAPA_2c09990 30d95533ec011ff03e8b067d685bcabe 97 SUPERFAMILY SSF54909 1 82 6.17E-11 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel VAPA_2c09990 30d95533ec011ff03e8b067d685bcabe 97 Pfam PF03795 YCII-related domain 13 81 2.0E-4 T 12-10-2018 IPR005545 YCII-related VAPA_1c32240 48a7686c1d43b30f75137ed0a3b75802 457 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 112 317 1.0E-40 T 12-10-2018 IPR000477 Reverse transcriptase domain VAPA_1c32240 48a7686c1d43b30f75137ed0a3b75802 457 Pfam PF08388 Group II intron, maturase-specific domain 336 403 1.2E-14 T 12-10-2018 IPR013597 Group II intron, maturase-specific VAPA_1c32240 48a7686c1d43b30f75137ed0a3b75802 457 TIGRFAM TIGR04416 group_II_RT_mat: group II intron reverse transcriptase/maturase 56 399 8.4E-122 T 12-10-2018 IPR030931 Group II intron reverse transcriptase/maturase VAPA_1c32240 48a7686c1d43b30f75137ed0a3b75802 457 SUPERFAMILY SSF56672 61 394 4.18E-47 T 12-10-2018 VAPA_1c07270 fbea1e6c215e20edfacbdcbbe3cf0db6 219 Pfam PF01810 LysE type translocator 17 209 1.8E-34 T 12-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 VAPA_1c07270 fbea1e6c215e20edfacbdcbbe3cf0db6 219 PIRSF PIRSF006324 1 212 6.9E-57 T 12-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 VAPA_1c19070 9993d54d1a501216e6e7fc387de7c6d6 469 Gene3D G3DSA:3.40.50.300 182 463 4.7E-107 T 12-10-2018 VAPA_1c19070 9993d54d1a501216e6e7fc387de7c6d6 469 Gene3D G3DSA:1.10.860.10 16 181 1.3E-51 T 12-10-2018 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal VAPA_1c19070 9993d54d1a501216e6e7fc387de7c6d6 469 TIGRFAM TIGR00665 DnaB: replicative DNA helicase 24 461 1.5E-174 T 12-10-2018 IPR007692 DNA helicase, DnaB type GO:0003677|GO:0003678|GO:0005524|GO:0006260 VAPA_1c19070 9993d54d1a501216e6e7fc387de7c6d6 469 Pfam PF00772 DnaB-like helicase N terminal domain 24 125 7.3E-31 T 12-10-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 VAPA_1c19070 9993d54d1a501216e6e7fc387de7c6d6 469 SUPERFAMILY SSF48024 22 133 1.57E-35 T 12-10-2018 IPR036185 DNA helicase, DnaB-like, N-terminal domain superfamily GO:0003678|GO:0005524|GO:0006260 VAPA_1c19070 9993d54d1a501216e6e7fc387de7c6d6 469 Pfam PF03796 DnaB-like helicase C terminal domain 202 459 7.2E-112 T 12-10-2018 IPR007694 DNA helicase, DnaB-like, C-terminal GO:0003678|GO:0005524|GO:0006260 Reactome: R-HSA-2151201 VAPA_1c19070 9993d54d1a501216e6e7fc387de7c6d6 469 SMART SM00382 219 419 7.8E-5 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c19070 9993d54d1a501216e6e7fc387de7c6d6 469 SUPERFAMILY SSF52540 200 451 1.49E-50 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c07610 d61a5282795dd2769a881c04aecfcc85 368 SUPERFAMILY SSF63829 37 366 1.57E-62 T 12-10-2018 VAPA_1c07610 d61a5282795dd2769a881c04aecfcc85 368 Pfam PF08450 SMP-30/Gluconolaconase/LRE-like region 72 355 1.2E-56 T 12-10-2018 IPR013658 SMP-30/Gluconolactonase/LRE-like region VAPA_1c07610 d61a5282795dd2769a881c04aecfcc85 368 Gene3D G3DSA:2.120.10.30 45 368 6.0E-95 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like VAPA_1c07610 d61a5282795dd2769a881c04aecfcc85 368 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 73 90 7.1E-5 T 12-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) VAPA_1c07610 d61a5282795dd2769a881c04aecfcc85 368 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 204 226 7.1E-5 T 12-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) VAPA_1c07610 d61a5282795dd2769a881c04aecfcc85 368 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 269 286 7.1E-5 T 12-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) VAPA_1c39150 202e04f8ae6d87e5cb62f0c202332303 338 Gene3D G3DSA:3.30.540.10 1 199 8.9E-72 T 12-10-2018 VAPA_1c39150 202e04f8ae6d87e5cb62f0c202332303 338 SUPERFAMILY SSF56655 3 334 8.7E-118 T 12-10-2018 VAPA_1c39150 202e04f8ae6d87e5cb62f0c202332303 338 Pfam PF00316 Fructose-1-6-bisphosphatase, N-terminal domain 8 197 1.9E-62 T 12-10-2018 IPR033391 Fructose-1-6-bisphosphatase class I, N-terminal KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 VAPA_1c39150 202e04f8ae6d87e5cb62f0c202332303 338 Hamap MF_01855 Fructose-1,6-bisphosphatase class 1 [fbp]. 7 336 47.347 T 12-10-2018 IPR000146 Fructose-1,6-bisphosphatase class 1 GO:0005975|GO:0016791 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 VAPA_1c39150 202e04f8ae6d87e5cb62f0c202332303 338 PIRSF PIRSF000904 3 338 1.3E-125 T 12-10-2018 IPR000146 Fructose-1,6-bisphosphatase class 1 GO:0005975|GO:0016791 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 VAPA_1c39150 202e04f8ae6d87e5cb62f0c202332303 338 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 151 174 1.7E-71 T 12-10-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 VAPA_1c39150 202e04f8ae6d87e5cb62f0c202332303 338 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 69 95 1.7E-71 T 12-10-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 VAPA_1c39150 202e04f8ae6d87e5cb62f0c202332303 338 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 310 335 1.7E-71 T 12-10-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 VAPA_1c39150 202e04f8ae6d87e5cb62f0c202332303 338 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 32 59 1.7E-71 T 12-10-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 VAPA_1c39150 202e04f8ae6d87e5cb62f0c202332303 338 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 182 205 1.7E-71 T 12-10-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 VAPA_1c39150 202e04f8ae6d87e5cb62f0c202332303 338 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 208 235 1.7E-71 T 12-10-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 VAPA_1c39150 202e04f8ae6d87e5cb62f0c202332303 338 Gene3D G3DSA:3.40.190.80 200 337 2.9E-55 T 12-10-2018 VAPA_1c39150 202e04f8ae6d87e5cb62f0c202332303 338 PIRSF PIRSF500210 3 338 3.6E-128 T 12-10-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 VAPA_1c17110 9d4224712d5adbcc58add0c731c41453 293 Gene3D G3DSA:3.40.50.720 3 177 1.2E-54 T 12-10-2018 VAPA_1c17110 9d4224712d5adbcc58add0c731c41453 293 Pfam PF02153 Prephenate dehydrogenase 17 270 2.5E-69 T 12-10-2018 IPR003099 Prephenate dehydrogenase GO:0004665|GO:0006571|GO:0008977|GO:0055114 KEGG: 00400+1.3.1.12|KEGG: 00401+1.3.1.12|MetaCyc: PWY-7303 VAPA_1c17110 9d4224712d5adbcc58add0c731c41453 293 SUPERFAMILY SSF51735 5 172 1.75E-44 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c17110 9d4224712d5adbcc58add0c731c41453 293 Gene3D G3DSA:1.10.3660.10 178 285 7.1E-31 T 12-10-2018 VAPA_1c17110 9d4224712d5adbcc58add0c731c41453 293 SUPERFAMILY SSF48179 175 283 5.55E-29 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 VAPA_1c08250 31deb4c5e88922546d8fea56066fccc8 1357 Gene3D G3DSA:3.40.50.2000 1131 1347 2.2E-36 T 12-10-2018 VAPA_1c08250 31deb4c5e88922546d8fea56066fccc8 1357 Pfam PF00535 Glycosyl transferase family 2 424 601 7.3E-22 T 12-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 VAPA_1c08250 31deb4c5e88922546d8fea56066fccc8 1357 Pfam PF00535 Glycosyl transferase family 2 183 284 2.7E-8 T 12-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 VAPA_1c08250 31deb4c5e88922546d8fea56066fccc8 1357 Pfam PF00534 Glycosyl transferases group 1 1158 1321 4.0E-14 T 12-10-2018 IPR001296 Glycosyl transferase, family 1 VAPA_1c08250 31deb4c5e88922546d8fea56066fccc8 1357 Gene3D G3DSA:3.90.550.10 405 649 3.3E-48 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases VAPA_1c08250 31deb4c5e88922546d8fea56066fccc8 1357 SUPERFAMILY SSF53448 418 649 2.53E-51 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases VAPA_1c08250 31deb4c5e88922546d8fea56066fccc8 1357 Gene3D G3DSA:3.90.550.10 139 400 1.0E-24 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases VAPA_1c08250 31deb4c5e88922546d8fea56066fccc8 1357 SUPERFAMILY SSF53756 993 1339 6.73E-36 T 12-10-2018 VAPA_1c08250 31deb4c5e88922546d8fea56066fccc8 1357 SUPERFAMILY SSF53448 167 369 2.81E-24 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases VAPA_1c51810 e41f0a9431c115787a50f91ae0984184 919 SUPERFAMILY SSF47384 679 750 6.28E-14 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 VAPA_1c51810 e41f0a9431c115787a50f91ae0984184 919 Gene3D G3DSA:1.10.287.130 677 751 2.8E-14 T 12-10-2018 VAPA_1c51810 e41f0a9431c115787a50f91ae0984184 919 Gene3D G3DSA:3.30.450.40 536 676 9.1E-33 T 12-10-2018 IPR029016 GAF-like domain superfamily VAPA_1c51810 e41f0a9431c115787a50f91ae0984184 919 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 803 907 3.6E-18 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase VAPA_1c51810 e41f0a9431c115787a50f91ae0984184 919 Pfam PF00512 His Kinase A (phospho-acceptor) domain 687 750 1.0E-12 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 VAPA_1c51810 e41f0a9431c115787a50f91ae0984184 919 SUPERFAMILY SSF55874 739 909 9.43E-35 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_1c51810 e41f0a9431c115787a50f91ae0984184 919 PRINTS PR00344 Bacterial sensor protein C-terminal signature 854 864 6.9E-15 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c51810 e41f0a9431c115787a50f91ae0984184 919 PRINTS PR00344 Bacterial sensor protein C-terminal signature 869 887 6.9E-15 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c51810 e41f0a9431c115787a50f91ae0984184 919 PRINTS PR00344 Bacterial sensor protein C-terminal signature 833 847 6.9E-15 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c51810 e41f0a9431c115787a50f91ae0984184 919 PRINTS PR00344 Bacterial sensor protein C-terminal signature 893 906 6.9E-15 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c51810 e41f0a9431c115787a50f91ae0984184 919 SMART SM00388 686 750 1.6E-15 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 VAPA_1c51810 e41f0a9431c115787a50f91ae0984184 919 Pfam PF02702 Osmosensitive K+ channel His kinase sensor domain 24 232 9.4E-95 T 12-10-2018 IPR003852 Signal transduction histidine kinase, osmosensitive K+ channel sensor, N-terminal GO:0000155|GO:0000160|GO:0004673|GO:0016020 VAPA_1c51810 e41f0a9431c115787a50f91ae0984184 919 Gene3D G3DSA:3.30.565.10 761 911 3.4E-33 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_1c51810 e41f0a9431c115787a50f91ae0984184 919 SMART SM00387 798 909 8.0E-26 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase VAPA_1c51810 e41f0a9431c115787a50f91ae0984184 919 Pfam PF13493 Domain of unknown function (DUF4118) 427 527 8.9E-28 T 12-10-2018 IPR025201 Sensor protein KdpD, transmembrane domain VAPA_1c51810 e41f0a9431c115787a50f91ae0984184 919 SUPERFAMILY SSF52402 267 362 3.68E-6 T 12-10-2018 VAPA_1c51810 e41f0a9431c115787a50f91ae0984184 919 SUPERFAMILY SSF55781 533 670 1.44E-7 T 12-10-2018 VAPA_1c51810 e41f0a9431c115787a50f91ae0984184 919 Gene3D G3DSA:3.40.50.620 257 373 5.6E-6 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold VAPA_1c51810 e41f0a9431c115787a50f91ae0984184 919 Gene3D G3DSA:1.20.120.620 422 527 7.7E-33 T 12-10-2018 IPR038318 KdpD, transmembrane domain superfamily VAPA_1c51810 e41f0a9431c115787a50f91ae0984184 919 Gene3D G3DSA:3.40.50.300 22 231 8.5E-97 T 12-10-2018 VAPA_1c51810 e41f0a9431c115787a50f91ae0984184 919 Pfam PF13492 GAF domain 595 667 1.8E-9 T 12-10-2018 IPR003018 GAF domain GO:0005515 VAPA_1c36620 1d54ede8ff61c1f7513676e9d20ea9c8 321 Gene3D G3DSA:3.40.190.150 26 311 3.1E-114 T 12-10-2018 VAPA_1c36620 1d54ede8ff61c1f7513676e9d20ea9c8 321 SUPERFAMILY SSF53850 112 281 7.24E-7 T 12-10-2018 VAPA_1c36620 1d54ede8ff61c1f7513676e9d20ea9c8 321 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 45 318 5.8E-88 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c36620 1d54ede8ff61c1f7513676e9d20ea9c8 321 PIRSF PIRSF017082 1 320 7.8E-86 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c36620 1d54ede8ff61c1f7513676e9d20ea9c8 321 Gene3D G3DSA:3.40.190.10 124 246 3.1E-114 T 12-10-2018 VAPA_1c03040 347141d2d9aa5b92360d5cfd0d85aa5d 794 TIGRFAM TIGR01646 vgr_GE: Rhs element Vgr protein 28 523 1.3E-136 T 12-10-2018 IPR006533 Type VI secretion system, RhsGE-associated Vgr protein VAPA_1c03040 347141d2d9aa5b92360d5cfd0d85aa5d 794 Gene3D G3DSA:3.55.50.10 117 207 1.2E-97 T 12-10-2018 VAPA_1c03040 347141d2d9aa5b92360d5cfd0d85aa5d 794 SUPERFAMILY SSF69279 214 377 9.01E-36 T 12-10-2018 VAPA_1c03040 347141d2d9aa5b92360d5cfd0d85aa5d 794 Gene3D G3DSA:3.30.1920.30 243 305 1.2E-97 T 12-10-2018 VAPA_1c03040 347141d2d9aa5b92360d5cfd0d85aa5d 794 Gene3D G3DSA:2.40.50.230 372 474 6.2E-42 T 12-10-2018 IPR037026 Vgr protein, OB-fold domain superfamily VAPA_1c03040 347141d2d9aa5b92360d5cfd0d85aa5d 794 Pfam PF05954 Phage late control gene D protein (GPD) 34 347 1.8E-88 T 12-10-2018 VAPA_1c03040 347141d2d9aa5b92360d5cfd0d85aa5d 794 Gene3D G3DSA:2.30.110.50 22 348 1.2E-97 T 12-10-2018 VAPA_1c03040 347141d2d9aa5b92360d5cfd0d85aa5d 794 SUPERFAMILY SSF69349 459 661 7.14E-50 T 12-10-2018 VAPA_1c03040 347141d2d9aa5b92360d5cfd0d85aa5d 794 TIGRFAM TIGR03361 VI_Rhs_Vgr: type VI secretion system Vgr family protein 22 541 2.5E-167 T 12-10-2018 IPR017847 Type VI secretion system, RhsGE-associated Vgr family subset VAPA_1c03040 347141d2d9aa5b92360d5cfd0d85aa5d 794 SUPERFAMILY SSF69255 381 469 4.18E-32 T 12-10-2018 VAPA_1c03040 347141d2d9aa5b92360d5cfd0d85aa5d 794 SUPERFAMILY SSF69279 24 203 1.66E-48 T 12-10-2018 VAPA_1c02350 f8e8d3136104d678b5f46874ad66c8bd 918 Gene3D G3DSA:3.40.50.300 178 370 1.1E-64 T 12-10-2018 VAPA_1c02350 f8e8d3136104d678b5f46874ad66c8bd 918 Gene3D G3DSA:1.10.1780.10 1 161 4.2E-41 T 12-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 VAPA_1c02350 f8e8d3136104d678b5f46874ad66c8bd 918 SMART SM01086 821 913 2.0E-12 T 12-10-2018 IPR019489 Clp ATPase, C-terminal VAPA_1c02350 f8e8d3136104d678b5f46874ad66c8bd 918 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 653 671 4.7E-33 T 12-10-2018 IPR001270 ClpA/B family GO:0005524 VAPA_1c02350 f8e8d3136104d678b5f46874ad66c8bd 918 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 760 774 4.7E-33 T 12-10-2018 IPR001270 ClpA/B family GO:0005524 VAPA_1c02350 f8e8d3136104d678b5f46874ad66c8bd 918 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 727 745 4.7E-33 T 12-10-2018 IPR001270 ClpA/B family GO:0005524 VAPA_1c02350 f8e8d3136104d678b5f46874ad66c8bd 918 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 698 716 4.7E-33 T 12-10-2018 IPR001270 ClpA/B family GO:0005524 VAPA_1c02350 f8e8d3136104d678b5f46874ad66c8bd 918 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 322 334 - T 12-10-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 VAPA_1c02350 f8e8d3136104d678b5f46874ad66c8bd 918 Gene3D G3DSA:3.40.50.300 602 819 3.7E-65 T 12-10-2018 VAPA_1c02350 f8e8d3136104d678b5f46874ad66c8bd 918 SUPERFAMILY SSF52540 598 888 1.24E-62 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c02350 f8e8d3136104d678b5f46874ad66c8bd 918 Pfam PF07724 AAA domain (Cdc48 subfamily) 648 814 2.5E-39 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 VAPA_1c02350 f8e8d3136104d678b5f46874ad66c8bd 918 TIGRFAM TIGR03345 VI_ClpV1: type VI secretion ATPase, ClpV1 family 13 905 0.0 T 12-10-2018 IPR017729 Type VI secretion system, ATPase ClpV1 VAPA_1c02350 f8e8d3136104d678b5f46874ad66c8bd 918 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 231 362 2.3E-9 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 VAPA_1c02350 f8e8d3136104d678b5f46874ad66c8bd 918 SMART SM00382 226 371 3.0E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c02350 f8e8d3136104d678b5f46874ad66c8bd 918 SMART SM00382 649 811 1.3E-9 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c02350 f8e8d3136104d678b5f46874ad66c8bd 918 SUPERFAMILY SSF81923 12 132 8.37E-18 T 12-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 VAPA_1c02350 f8e8d3136104d678b5f46874ad66c8bd 918 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 26 75 3.0E-4 T 12-10-2018 IPR004176 Clp, N-terminal VAPA_1c02350 f8e8d3136104d678b5f46874ad66c8bd 918 Gene3D G3DSA:1.10.8.60 821 917 6.6E-12 T 12-10-2018 VAPA_1c02350 f8e8d3136104d678b5f46874ad66c8bd 918 Gene3D G3DSA:3.40.50.300 372 596 9.2E-39 T 12-10-2018 VAPA_1c02350 f8e8d3136104d678b5f46874ad66c8bd 918 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 821 895 6.9E-13 T 12-10-2018 IPR019489 Clp ATPase, C-terminal VAPA_1c02350 f8e8d3136104d678b5f46874ad66c8bd 918 SUPERFAMILY SSF52540 188 510 5.96E-72 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c18290 d42c677b61d06221cbeb25cf101d5e01 239 Pfam PF09209 Domain of unknown function (DUF1956) 102 219 8.5E-13 T 12-10-2018 IPR015292 Transcription regulator YbiH, C-terminal VAPA_1c18290 d42c677b61d06221cbeb25cf101d5e01 239 Pfam PF00440 Bacterial regulatory proteins, tetR family 32 78 3.4E-12 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 VAPA_1c18290 d42c677b61d06221cbeb25cf101d5e01 239 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 32 45 1.6E-7 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 VAPA_1c18290 d42c677b61d06221cbeb25cf101d5e01 239 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 53 76 1.6E-7 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 VAPA_1c18290 d42c677b61d06221cbeb25cf101d5e01 239 Gene3D G3DSA:1.10.357.10 20 229 5.7E-30 T 12-10-2018 VAPA_1c18290 d42c677b61d06221cbeb25cf101d5e01 239 SUPERFAMILY SSF46689 20 88 2.26E-15 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 VAPA_1c18290 d42c677b61d06221cbeb25cf101d5e01 239 SUPERFAMILY SSF48498 98 220 5.93E-14 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily VAPA_2c08280 ef53d648d71c369c6d030be4a5a75be1 395 TIGRFAM TIGR01514 NAPRTase: nicotinate phosphoribosyltransferase 4 394 4.8E-152 T 12-10-2018 IPR006406 Nicotinate phosphoribosyltransferase GO:0004516|GO:0019357 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 VAPA_2c08280 ef53d648d71c369c6d030be4a5a75be1 395 Gene3D G3DSA:3.20.140.10 1 395 8.6E-147 T 12-10-2018 VAPA_2c08280 ef53d648d71c369c6d030be4a5a75be1 395 Pfam PF04095 Nicotinate phosphoribosyltransferase (NAPRTase) family 168 394 5.9E-75 T 12-10-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 VAPA_2c08280 ef53d648d71c369c6d030be4a5a75be1 395 PIRSF PIRSF000484 1 383 9.5E-67 T 12-10-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 VAPA_2c08280 ef53d648d71c369c6d030be4a5a75be1 395 Hamap MF_00570 Nicotinate phosphoribosyltransferase [pncB]. 1 395 45.623 T 12-10-2018 IPR006406 Nicotinate phosphoribosyltransferase GO:0004516|GO:0019357 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 VAPA_2c08280 ef53d648d71c369c6d030be4a5a75be1 395 SUPERFAMILY SSF51690 119 393 3.92E-85 T 12-10-2018 IPR036068 Nicotinate phosphoribosyltransferase-like, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 VAPA_2c08280 ef53d648d71c369c6d030be4a5a75be1 395 SUPERFAMILY SSF54675 1 137 2.35E-40 T 12-10-2018 VAPA_1c43320 5c0c3857a059f48a9e2d53668df685db 333 SUPERFAMILY SSF103039 53 232 4.45E-19 T 12-10-2018 IPR028976 CheC-like superfamily VAPA_1c43320 5c0c3857a059f48a9e2d53668df685db 333 Gene3D G3DSA:3.40.1550.10 46 234 3.5E-54 T 12-10-2018 IPR028976 CheC-like superfamily VAPA_1c43320 5c0c3857a059f48a9e2d53668df685db 333 PRINTS PR00955 Flagellar motor switch protein FliM signature 214 232 3.8E-26 T 12-10-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 VAPA_1c43320 5c0c3857a059f48a9e2d53668df685db 333 PRINTS PR00955 Flagellar motor switch protein FliM signature 116 135 3.8E-26 T 12-10-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 VAPA_1c43320 5c0c3857a059f48a9e2d53668df685db 333 PRINTS PR00955 Flagellar motor switch protein FliM signature 4 17 3.8E-26 T 12-10-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 VAPA_1c43320 5c0c3857a059f48a9e2d53668df685db 333 PRINTS PR00955 Flagellar motor switch protein FliM signature 91 107 3.8E-26 T 12-10-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 VAPA_1c43320 5c0c3857a059f48a9e2d53668df685db 333 SUPERFAMILY SSF101801 250 325 1.44E-12 T 12-10-2018 IPR036429 SpoA-like superfamily VAPA_1c43320 5c0c3857a059f48a9e2d53668df685db 333 TIGRFAM TIGR01397 fliM_switch: flagellar motor switch protein FliM 5 321 5.4E-98 T 12-10-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 VAPA_1c43320 5c0c3857a059f48a9e2d53668df685db 333 Pfam PF01052 Type III flagellar switch regulator (C-ring) FliN C-term 252 321 7.8E-17 T 12-10-2018 IPR001543 Surface presentation of antigen (SpoA) VAPA_1c43320 5c0c3857a059f48a9e2d53668df685db 333 PIRSF PIRSF002888 3 331 5.2E-89 T 12-10-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 VAPA_1c43320 5c0c3857a059f48a9e2d53668df685db 333 Pfam PF02154 Flagellar motor switch protein FliM 40 232 2.7E-69 T 12-10-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 VAPA_2c02180 5ffb5430699469d93328a6ed74d9b132 234 Gene3D G3DSA:3.40.50.720 3 233 1.6E-54 T 12-10-2018 VAPA_2c02180 5ffb5430699469d93328a6ed74d9b132 234 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 123 131 1.6E-5 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c02180 5ffb5430699469d93328a6ed74d9b132 234 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 142 161 1.6E-5 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c02180 5ffb5430699469d93328a6ed74d9b132 234 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 70 81 1.6E-5 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c02180 5ffb5430699469d93328a6ed74d9b132 234 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 230 5.9E-36 T 12-10-2018 VAPA_2c02180 5ffb5430699469d93328a6ed74d9b132 234 SUPERFAMILY SSF51735 9 233 6.29E-53 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_2c02180 5ffb5430699469d93328a6ed74d9b132 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 117 133 3.0E-33 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c02180 5ffb5430699469d93328a6ed74d9b132 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 3.0E-33 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c02180 5ffb5430699469d93328a6ed74d9b132 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 70 81 3.0E-33 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c02180 5ffb5430699469d93328a6ed74d9b132 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 163 180 3.0E-33 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c02180 5ffb5430699469d93328a6ed74d9b132 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 194 214 3.0E-33 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c02180 5ffb5430699469d93328a6ed74d9b132 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 142 161 3.0E-33 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c06140 ce8e64973be4591fa6bc51f855b080b9 337 SUPERFAMILY SSF52540 9 262 2.66E-58 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_2c06140 ce8e64973be4591fa6bc51f855b080b9 337 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 243 307 1.5E-19 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 VAPA_2c06140 ce8e64973be4591fa6bc51f855b080b9 337 ProSitePatterns PS00211 ABC transporters family signature. 164 178 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_2c06140 ce8e64973be4591fa6bc51f855b080b9 337 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 241 324 6.9E-24 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 VAPA_2c06140 ce8e64973be4591fa6bc51f855b080b9 337 Gene3D G3DSA:3.40.50.300 6 328 3.5E-90 T 12-10-2018 VAPA_2c06140 ce8e64973be4591fa6bc51f855b080b9 337 SMART SM00382 37 241 2.4E-12 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_2c06140 ce8e64973be4591fa6bc51f855b080b9 337 Pfam PF00005 ABC transporter 29 191 2.4E-25 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c17560 5a14c9a93338f8084e7cf99e89c3613b 123 SUPERFAMILY SSF50090 13 118 1.14E-26 T 12-10-2018 IPR008990 Electron transport accessory-like domain superfamily VAPA_1c17560 5a14c9a93338f8084e7cf99e89c3613b 123 Gene3D G3DSA:1.10.472.20 11 116 3.2E-19 T 12-10-2018 VAPA_1c17560 5a14c9a93338f8084e7cf99e89c3613b 123 Pfam PF02211 Nitrile hydratase beta subunit 17 102 5.3E-11 T 12-10-2018 IPR024690 Nitrile hydratase beta subunit domain GO:0018822 KEGG: 00364+4.2.1.84|KEGG: 00380+4.2.1.84|KEGG: 00627+4.2.1.84|KEGG: 00643+4.2.1.84|MetaCyc: PWY-5025|MetaCyc: PWY-581|MetaCyc: PWY-7308 VAPA_1c17560 5a14c9a93338f8084e7cf99e89c3613b 123 TIGRFAM TIGR03889 nitrile_acc: nitrile hydratase accessory protein 23 94 1.4E-28 T 12-10-2018 IPR023808 Nitrile hydratase accessory protein, putative VAPA_1c33620 427ca2bbf296dbb58e3257c0250f0c28 300 PIRSF PIRSF000103 1 300 4.5E-80 T 12-10-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 VAPA_1c33620 427ca2bbf296dbb58e3257c0250f0c28 300 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 2 165 5.3E-51 T 12-10-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 VAPA_1c33620 427ca2bbf296dbb58e3257c0250f0c28 300 TIGRFAM TIGR01692 HIBADH: 3-hydroxyisobutyrate dehydrogenase 5 295 2.6E-124 T 12-10-2018 IPR011548 3-hydroxyisobutyrate dehydrogenase GO:0008442|GO:0051287|GO:0055114 KEGG: 00280+1.1.1.31|Reactome: R-HSA-70895 VAPA_1c33620 427ca2bbf296dbb58e3257c0250f0c28 300 SUPERFAMILY SSF51735 1 166 2.33E-45 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c33620 427ca2bbf296dbb58e3257c0250f0c28 300 ProSitePatterns PS00895 3-hydroxyisobutyrate dehydrogenase signature. 5 18 - T 12-10-2018 IPR002204 3-hydroxyisobutyrate dehydrogenase-related, conserved site GO:0016491|GO:0055114 Reactome: R-HSA-70895 VAPA_1c33620 427ca2bbf296dbb58e3257c0250f0c28 300 Gene3D G3DSA:1.10.1040.10 168 299 2.0E-45 T 12-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 VAPA_1c33620 427ca2bbf296dbb58e3257c0250f0c28 300 Gene3D G3DSA:3.40.50.720 1 166 4.7E-54 T 12-10-2018 VAPA_1c33620 427ca2bbf296dbb58e3257c0250f0c28 300 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 168 295 2.1E-36 T 12-10-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 VAPA_1c33620 427ca2bbf296dbb58e3257c0250f0c28 300 SUPERFAMILY SSF48179 166 297 1.47E-40 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 VAPA_1c47790 9a411e7405bd47a80bbb17be4cc25da6 363 Gene3D G3DSA:3.10.20.30 48 361 5.7E-148 T 12-10-2018 IPR012675 Beta-grasp domain superfamily VAPA_1c47790 9a411e7405bd47a80bbb17be4cc25da6 363 Hamap MF_00944 Ribosome-binding ATPase YchF [ychF]. 2 363 43.306 T 12-10-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 VAPA_1c47790 9a411e7405bd47a80bbb17be4cc25da6 363 Pfam PF01926 50S ribosome-binding GTPase 5 122 8.4E-22 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 VAPA_1c47790 9a411e7405bd47a80bbb17be4cc25da6 363 Pfam PF06071 Protein of unknown function (DUF933) 279 361 2.0E-35 T 12-10-2018 IPR013029 YchF, C-terminal domain Reactome: R-HSA-114608 VAPA_1c47790 9a411e7405bd47a80bbb17be4cc25da6 363 Gene3D G3DSA:1.10.150.300 113 200 5.7E-148 T 12-10-2018 IPR023192 TGS-like domain superfamily Reactome: R-HSA-114608 VAPA_1c47790 9a411e7405bd47a80bbb17be4cc25da6 363 Gene3D G3DSA:3.40.50.300 3 278 5.7E-148 T 12-10-2018 VAPA_1c47790 9a411e7405bd47a80bbb17be4cc25da6 363 SUPERFAMILY SSF81271 279 359 7.41E-33 T 12-10-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 VAPA_1c47790 9a411e7405bd47a80bbb17be4cc25da6 363 TIGRFAM TIGR00092 TIGR00092: GTP-binding protein YchF 1 362 5.2E-152 T 12-10-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 VAPA_1c47790 9a411e7405bd47a80bbb17be4cc25da6 363 PIRSF PIRSF006641 1 363 9.2E-150 T 12-10-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 VAPA_1c47790 9a411e7405bd47a80bbb17be4cc25da6 363 SUPERFAMILY SSF52540 3 299 4.43E-86 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c47790 9a411e7405bd47a80bbb17be4cc25da6 363 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 70 85 7.0E-33 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 VAPA_1c47790 9a411e7405bd47a80bbb17be4cc25da6 363 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 87 105 7.0E-33 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 VAPA_1c47790 9a411e7405bd47a80bbb17be4cc25da6 363 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 26 44 7.0E-33 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 VAPA_1c47790 9a411e7405bd47a80bbb17be4cc25da6 363 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 5 25 7.0E-33 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 VAPA_1c54000 5100840c97c2d24e76cda67c1a68af3b 388 ProSitePatterns PS01217 ATP-citrate lyase / succinyl-CoA ligases family signature 3. 257 282 - T 12-10-2018 IPR017866 Succinyl-CoA synthetase, beta subunit, conserved site KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 VAPA_1c54000 5100840c97c2d24e76cda67c1a68af3b 388 PIRSF PIRSF001554 1 388 1.7E-152 T 12-10-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 VAPA_1c54000 5100840c97c2d24e76cda67c1a68af3b 388 Gene3D G3DSA:3.30.470.20 1 234 1.5E-95 T 12-10-2018 VAPA_1c54000 5100840c97c2d24e76cda67c1a68af3b 388 SUPERFAMILY SSF56059 1 238 3.01E-84 T 12-10-2018 VAPA_1c54000 5100840c97c2d24e76cda67c1a68af3b 388 Pfam PF00549 CoA-ligase 262 382 4.2E-26 T 12-10-2018 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 VAPA_1c54000 5100840c97c2d24e76cda67c1a68af3b 388 SUPERFAMILY SSF52210 241 385 1.44E-53 T 12-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 VAPA_1c54000 5100840c97c2d24e76cda67c1a68af3b 388 Hamap MF_00558 Succinate--CoA ligase [ADP-forming] subunit beta [sucC]. 1 386 43.031 T 12-10-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 VAPA_1c54000 5100840c97c2d24e76cda67c1a68af3b 388 Pfam PF08442 ATP-grasp domain 2 201 5.5E-80 T 12-10-2018 IPR013650 ATP-grasp fold, succinyl-CoA synthetase-type KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 VAPA_1c54000 5100840c97c2d24e76cda67c1a68af3b 388 Gene3D G3DSA:3.40.50.261 240 388 4.7E-57 T 12-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 VAPA_1c54000 5100840c97c2d24e76cda67c1a68af3b 388 TIGRFAM TIGR01016 sucCoAbeta: succinate-CoA ligase, beta subunit 1 385 3.0E-157 T 12-10-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 VAPA_1c54000 5100840c97c2d24e76cda67c1a68af3b 388 Gene3D G3DSA:3.30.1490.20 21 104 1.5E-95 T 12-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 VAPA_1c19420 eb9370137f423f54e92489e8750186c6 238 Pfam PF01569 PAP2 superfamily 133 221 2.3E-9 T 12-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase VAPA_1c19420 eb9370137f423f54e92489e8750186c6 238 Gene3D G3DSA:1.20.144.10 135 227 2.8E-9 T 12-10-2018 VAPA_1c53940 23292ee0835084924be842a045ca70ba 267 Pfam PF12706 Beta-lactamase superfamily domain 27 223 4.0E-17 T 12-10-2018 IPR001279 Metallo-beta-lactamase VAPA_1c53940 23292ee0835084924be842a045ca70ba 267 PRINTS PR00388 3'5'-cyclic nucleotide class II phosphodiesterase signature 81 102 9.8E-9 T 12-10-2018 IPR000396 Cyclic-AMP phosphodiesterase, class-II GO:0004115|GO:0006198 VAPA_1c53940 23292ee0835084924be842a045ca70ba 267 PRINTS PR00388 3'5'-cyclic nucleotide class II phosphodiesterase signature 199 212 9.8E-9 T 12-10-2018 IPR000396 Cyclic-AMP phosphodiesterase, class-II GO:0004115|GO:0006198 VAPA_1c53940 23292ee0835084924be842a045ca70ba 267 PRINTS PR00388 3'5'-cyclic nucleotide class II phosphodiesterase signature 49 67 9.8E-9 T 12-10-2018 IPR000396 Cyclic-AMP phosphodiesterase, class-II GO:0004115|GO:0006198 VAPA_1c53940 23292ee0835084924be842a045ca70ba 267 SUPERFAMILY SSF56281 1 240 3.8E-35 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like VAPA_1c53940 23292ee0835084924be842a045ca70ba 267 SMART SM00849 17 207 6.4E-9 T 12-10-2018 IPR001279 Metallo-beta-lactamase VAPA_1c53940 23292ee0835084924be842a045ca70ba 267 Gene3D G3DSA:3.60.15.10 2 257 1.2E-31 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like VAPA_1c02060 7f01650226f6c7ceabb97d05ee8e2665 151 Pfam PF05232 Chlorhexidine efflux transporter 71 133 3.2E-26 T 12-10-2018 IPR007896 Chlorhexidine efflux transporter VAPA_1c02060 7f01650226f6c7ceabb97d05ee8e2665 151 Pfam PF05232 Chlorhexidine efflux transporter 3 65 1.2E-19 T 12-10-2018 IPR007896 Chlorhexidine efflux transporter VAPA_1c25650 12c3eb32e3e3782b4e428482841add9b 343 SUPERFAMILY SSF51569 3 334 5.76E-126 T 12-10-2018 VAPA_1c25650 12c3eb32e3e3782b4e428482841add9b 343 Pfam PF00274 Fructose-bisphosphate aldolase class-I 6 334 3.5E-132 T 12-10-2018 IPR000741 Fructose-bisphosphate aldolase, class-I GO:0004332|GO:0006096 KEGG: 00010+4.1.2.13|KEGG: 00030+4.1.2.13|KEGG: 00051+4.1.2.13|KEGG: 00680+4.1.2.13|KEGG: 00710+4.1.2.13|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385|Reactome: R-HSA-70171|Reactome: R-HSA-70263 VAPA_1c25650 12c3eb32e3e3782b4e428482841add9b 343 Gene3D G3DSA:3.20.20.70 1 342 8.1E-149 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 VAPA_1c25650 12c3eb32e3e3782b4e428482841add9b 343 ProSitePatterns PS00158 Fructose-bisphosphate aldolase class-I active site. 211 221 - T 12-10-2018 IPR029768 Fructose-bisphosphate aldolase class-I active site KEGG: 00010+4.1.2.13|KEGG: 00030+4.1.2.13|KEGG: 00051+4.1.2.13|KEGG: 00680+4.1.2.13|KEGG: 00710+4.1.2.13|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385|Reactome: R-HSA-70171|Reactome: R-HSA-70263 VAPA_2c00430 18b0173eea208e0951a264c5e7f0da87 229 Gene3D G3DSA:1.10.10.10 9 84 7.5E-21 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_2c00430 18b0173eea208e0951a264c5e7f0da87 229 SMART SM00345 25 83 2.8E-17 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_2c00430 18b0173eea208e0951a264c5e7f0da87 229 Pfam PF00392 Bacterial regulatory proteins, gntR family 24 83 3.2E-16 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_2c00430 18b0173eea208e0951a264c5e7f0da87 229 Gene3D G3DSA:1.20.120.530 86 229 1.2E-28 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal VAPA_2c00430 18b0173eea208e0951a264c5e7f0da87 229 SMART SM00895 93 220 4.2E-18 T 12-10-2018 IPR011711 GntR, C-terminal VAPA_2c00430 18b0173eea208e0951a264c5e7f0da87 229 SUPERFAMILY SSF46785 14 87 1.04E-20 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_2c00430 18b0173eea208e0951a264c5e7f0da87 229 Pfam PF07729 FCD domain 93 219 1.6E-22 T 12-10-2018 IPR011711 GntR, C-terminal VAPA_2c00430 18b0173eea208e0951a264c5e7f0da87 229 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 43 57 9.0E-6 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_2c00430 18b0173eea208e0951a264c5e7f0da87 229 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 57 73 9.0E-6 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_2c00430 18b0173eea208e0951a264c5e7f0da87 229 SUPERFAMILY SSF48008 89 226 5.23E-26 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal VAPA_2c04150 42b3afbba1622ce488de597311c8edd4 337 SUPERFAMILY SSF52518 4 201 3.27E-65 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold VAPA_2c04150 42b3afbba1622ce488de597311c8edd4 337 SMART SM00861 4 189 4.6E-64 T 12-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain VAPA_2c04150 42b3afbba1622ce488de597311c8edd4 337 SUPERFAMILY SSF52922 198 333 3.4E-36 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 VAPA_2c04150 42b3afbba1622ce488de597311c8edd4 337 Gene3D G3DSA:3.40.50.920 202 334 1.1E-41 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 VAPA_2c04150 42b3afbba1622ce488de597311c8edd4 337 Gene3D G3DSA:3.40.50.970 1 201 1.4E-80 T 12-10-2018 VAPA_2c04150 42b3afbba1622ce488de597311c8edd4 337 Pfam PF02779 Transketolase, pyrimidine binding domain 5 188 3.6E-50 T 12-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain VAPA_2c04150 42b3afbba1622ce488de597311c8edd4 337 Pfam PF02780 Transketolase, C-terminal domain 203 325 1.7E-36 T 12-10-2018 IPR033248 Transketolase, C-terminal domain VAPA_1c34090 b08391515849d57232c9c8e47149568b 123 Pfam PF01597 Glycine cleavage H-protein 4 121 2.7E-40 T 12-10-2018 IPR033753 Glycine cleavage system H-protein/Simiate VAPA_1c34090 b08391515849d57232c9c8e47149568b 123 TIGRFAM TIGR00527 gcvH: glycine cleavage system H protein 3 120 2.5E-43 T 12-10-2018 IPR017453 Glycine cleavage system H-protein, subgroup GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 VAPA_1c34090 b08391515849d57232c9c8e47149568b 123 Hamap MF_00272 Glycine cleavage system H protein [gcvH]. 2 121 36.696 T 12-10-2018 IPR002930 Glycine cleavage system H-protein GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 VAPA_1c34090 b08391515849d57232c9c8e47149568b 123 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 43 72 - T 12-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 VAPA_1c34090 b08391515849d57232c9c8e47149568b 123 SUPERFAMILY SSF51230 3 120 3.67E-41 T 12-10-2018 IPR011053 Single hybrid motif VAPA_1c34090 b08391515849d57232c9c8e47149568b 123 Gene3D G3DSA:2.40.50.100 1 123 1.6E-47 T 12-10-2018 VAPA_2c12650 eb2ddd0721a84ddbefce87216cc4213b 177 Gene3D G3DSA:3.90.1140.10 4 173 5.4E-21 T 12-10-2018 VAPA_2c12650 eb2ddd0721a84ddbefce87216cc4213b 177 SUPERFAMILY SSF55144 16 170 3.66E-11 T 12-10-2018 IPR009097 Cyclic phosphodiesterase VAPA_2c12650 eb2ddd0721a84ddbefce87216cc4213b 177 Pfam PF13563 2'-5' RNA ligase superfamily 9 158 4.9E-21 T 12-10-2018 VAPA_1c36900 078268e7eaba470d6d80b2189d80bb15 322 SUPERFAMILY SSF53850 101 308 1.26E-35 T 12-10-2018 VAPA_1c36900 078268e7eaba470d6d80b2189d80bb15 322 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 38 48 7.4E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c36900 078268e7eaba470d6d80b2189d80bb15 322 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 48 59 7.4E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c36900 078268e7eaba470d6d80b2189d80bb15 322 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 27 38 7.4E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c36900 078268e7eaba470d6d80b2189d80bb15 322 SUPERFAMILY SSF46785 8 87 9.31E-20 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c36900 078268e7eaba470d6d80b2189d80bb15 322 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 12 71 4.7E-17 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c36900 078268e7eaba470d6d80b2189d80bb15 322 Gene3D G3DSA:3.40.190.10 101 287 5.4E-43 T 12-10-2018 VAPA_1c36900 078268e7eaba470d6d80b2189d80bb15 322 Gene3D G3DSA:3.40.190.10 175 277 5.4E-43 T 12-10-2018 VAPA_1c36900 078268e7eaba470d6d80b2189d80bb15 322 Gene3D G3DSA:1.10.10.10 9 96 2.4E-21 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c36900 078268e7eaba470d6d80b2189d80bb15 322 Pfam PF03466 LysR substrate binding domain 99 302 1.8E-33 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_2c04030 58504758644ae772e488bd1952ddb3b0 863 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 609 634 8.1E-16 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 VAPA_2c04030 58504758644ae772e488bd1952ddb3b0 863 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 436 454 8.1E-16 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 VAPA_2c04030 58504758644ae772e488bd1952ddb3b0 863 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 549 565 8.1E-16 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 VAPA_2c04030 58504758644ae772e488bd1952ddb3b0 863 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 577 593 8.1E-16 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 VAPA_2c04030 58504758644ae772e488bd1952ddb3b0 863 Pfam PF00689 Cation transporting ATPase, C-terminus 661 836 1.3E-29 T 12-10-2018 IPR006068 Cation-transporting P-type ATPase, C-terminal Reactome: R-HSA-936837 VAPA_2c04030 58504758644ae772e488bd1952ddb3b0 863 SUPERFAMILY SSF81665 7 842 6.54E-85 T 12-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 VAPA_2c04030 58504758644ae772e488bd1952ddb3b0 863 Gene3D G3DSA:1.20.1110.10 38 835 7.3E-191 T 12-10-2018 VAPA_2c04030 58504758644ae772e488bd1952ddb3b0 863 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 305 319 3.0E-39 T 12-10-2018 VAPA_2c04030 58504758644ae772e488bd1952ddb3b0 863 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 577 596 3.0E-39 T 12-10-2018 VAPA_2c04030 58504758644ae772e488bd1952ddb3b0 863 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 498 508 3.0E-39 T 12-10-2018 VAPA_2c04030 58504758644ae772e488bd1952ddb3b0 863 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 601 613 3.0E-39 T 12-10-2018 VAPA_2c04030 58504758644ae772e488bd1952ddb3b0 863 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 145 159 3.0E-39 T 12-10-2018 VAPA_2c04030 58504758644ae772e488bd1952ddb3b0 863 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 476 487 3.0E-39 T 12-10-2018 VAPA_2c04030 58504758644ae772e488bd1952ddb3b0 863 Gene3D G3DSA:2.70.150.10 7 208 7.3E-191 T 12-10-2018 VAPA_2c04030 58504758644ae772e488bd1952ddb3b0 863 Pfam PF00122 E1-E2 ATPase 95 284 4.5E-43 T 12-10-2018 VAPA_2c04030 58504758644ae772e488bd1952ddb3b0 863 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 307 313 - T 12-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 VAPA_2c04030 58504758644ae772e488bd1952ddb3b0 863 Gene3D G3DSA:3.40.50.1000 302 622 7.3E-191 T 12-10-2018 IPR023214 HAD superfamily VAPA_2c04030 58504758644ae772e488bd1952ddb3b0 863 SUPERFAMILY SSF56784 303 677 5.15E-55 T 12-10-2018 IPR036412 HAD-like superfamily VAPA_2c04030 58504758644ae772e488bd1952ddb3b0 863 SUPERFAMILY SSF81660 315 483 9.16E-22 T 12-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 VAPA_2c04030 58504758644ae772e488bd1952ddb3b0 863 SUPERFAMILY SSF81653 97 202 3.01E-27 T 12-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 VAPA_2c04030 58504758644ae772e488bd1952ddb3b0 863 Pfam PF00702 haloacid dehalogenase-like hydrolase 303 591 1.3E-25 T 12-10-2018 VAPA_2c04030 58504758644ae772e488bd1952ddb3b0 863 Pfam PF00690 Cation transporter/ATPase, N-terminus 7 52 1.2E-4 T 12-10-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 VAPA_2c04030 58504758644ae772e488bd1952ddb3b0 863 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 548 667 2.2E-31 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 VAPA_2c04030 58504758644ae772e488bd1952ddb3b0 863 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 67 349 8.9E-35 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 VAPA_2c04030 58504758644ae772e488bd1952ddb3b0 863 Gene3D G3DSA:3.40.1110.10 315 483 7.3E-191 T 12-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 VAPA_2c08680 8fa5160655d506e59ab8cbc48ce70e82 586 Gene3D G3DSA:3.50.50.60 473 583 1.6E-10 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_2c08680 8fa5160655d506e59ab8cbc48ce70e82 586 SUPERFAMILY SSF51905 10 577 1.88E-41 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_2c08680 8fa5160655d506e59ab8cbc48ce70e82 586 SUPERFAMILY SSF54373 392 501 1.41E-10 T 12-10-2018 VAPA_2c08680 8fa5160655d506e59ab8cbc48ce70e82 586 Pfam PF00732 GMC oxidoreductase 201 348 6.1E-9 T 12-10-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 VAPA_2c08680 8fa5160655d506e59ab8cbc48ce70e82 586 Pfam PF05199 GMC oxidoreductase 444 571 5.1E-21 T 12-10-2018 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 VAPA_1c19160 ccbef253b06bfd505f0b167e5a521ef8 440 Gene3D G3DSA:3.30.360.10 136 348 4.7E-162 T 12-10-2018 VAPA_1c19160 ccbef253b06bfd505f0b167e5a521ef8 440 SUPERFAMILY SSF55347 137 302 4.9E-51 T 12-10-2018 VAPA_1c19160 ccbef253b06bfd505f0b167e5a521ef8 440 Gene3D G3DSA:3.30.70.260 349 427 4.7E-162 T 12-10-2018 VAPA_1c19160 ccbef253b06bfd505f0b167e5a521ef8 440 ProSitePatterns PS01042 Homoserine dehydrogenase signature. 183 205 - T 12-10-2018 IPR019811 Homoserine dehydrogenase, conserved site GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 VAPA_1c19160 ccbef253b06bfd505f0b167e5a521ef8 440 SUPERFAMILY SSF55021 352 429 1.91E-10 T 12-10-2018 VAPA_1c19160 ccbef253b06bfd505f0b167e5a521ef8 440 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 10 129 1.3E-19 T 12-10-2018 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 VAPA_1c19160 ccbef253b06bfd505f0b167e5a521ef8 440 Pfam PF01842 ACT domain 354 425 2.2E-12 T 12-10-2018 IPR002912 ACT domain VAPA_1c19160 ccbef253b06bfd505f0b167e5a521ef8 440 Pfam PF00742 Homoserine dehydrogenase 137 315 4.1E-63 T 12-10-2018 IPR001342 Homoserine dehydrogenase, catalytic GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 VAPA_1c19160 ccbef253b06bfd505f0b167e5a521ef8 440 SUPERFAMILY SSF51735 1 158 4.51E-36 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c19160 ccbef253b06bfd505f0b167e5a521ef8 440 Gene3D G3DSA:3.40.50.720 4 340 4.7E-162 T 12-10-2018 VAPA_1c19160 ccbef253b06bfd505f0b167e5a521ef8 440 PIRSF PIRSF000098 1 438 6.0E-161 T 12-10-2018 IPR016204 Homoserine dehydrogenase GO:0004412|GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 VAPA_1c17020 522fa52656dde5a7ba7149211008ffcb 433 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 11 423 4.8E-79 T 12-10-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit VAPA_1c17020 522fa52656dde5a7ba7149211008ffcb 433 TIGRFAM TIGR00786 dctM: TRAP transporter, DctM subunit 21 428 7.5E-116 T 12-10-2018 IPR004681 TRAP transporter large membrane protein DctM GO:0016021 VAPA_1c17020 522fa52656dde5a7ba7149211008ffcb 433 PIRSF PIRSF006066 5 433 4.1E-88 T 12-10-2018 IPR004681 TRAP transporter large membrane protein DctM GO:0016021 VAPA_1c03780 56fd2b5824192580b518f303577ff98b 557 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 190 327 5.6E-28 T 12-10-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 VAPA_1c03780 56fd2b5824192580b518f303577ff98b 557 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 6 171 9.3E-53 T 12-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 VAPA_1c03780 56fd2b5824192580b518f303577ff98b 557 Gene3D G3DSA:3.40.50.970 1 182 4.7E-61 T 12-10-2018 VAPA_1c03780 56fd2b5824192580b518f303577ff98b 557 SUPERFAMILY SSF52467 156 355 4.44E-37 T 12-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily VAPA_1c03780 56fd2b5824192580b518f303577ff98b 557 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 387 533 2.3E-41 T 12-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 VAPA_1c03780 56fd2b5824192580b518f303577ff98b 557 SUPERFAMILY SSF52518 5 178 6.8E-52 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold VAPA_1c03780 56fd2b5824192580b518f303577ff98b 557 Gene3D G3DSA:3.40.50.1220 185 352 3.1E-35 T 12-10-2018 VAPA_1c03780 56fd2b5824192580b518f303577ff98b 557 SUPERFAMILY SSF52518 363 543 1.97E-58 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold VAPA_1c03780 56fd2b5824192580b518f303577ff98b 557 Gene3D G3DSA:3.40.50.970 361 555 1.7E-58 T 12-10-2018 VAPA_1c11630 a63c47c444240a6825267a2688c42338 311 Gene3D G3DSA:1.10.10.10 16 103 4.6E-20 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c11630 a63c47c444240a6825267a2688c42338 311 Gene3D G3DSA:3.40.190.10 108 301 3.4E-45 T 12-10-2018 VAPA_1c11630 a63c47c444240a6825267a2688c42338 311 SUPERFAMILY SSF53850 102 309 7.61E-41 T 12-10-2018 VAPA_1c11630 a63c47c444240a6825267a2688c42338 311 SUPERFAMILY SSF46785 16 125 1.62E-22 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c11630 a63c47c444240a6825267a2688c42338 311 Gene3D G3DSA:3.40.190.10 181 283 3.4E-45 T 12-10-2018 VAPA_1c11630 a63c47c444240a6825267a2688c42338 311 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 19 77 7.2E-17 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c11630 a63c47c444240a6825267a2688c42338 311 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 44 54 3.5E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c11630 a63c47c444240a6825267a2688c42338 311 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 33 44 3.5E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c11630 a63c47c444240a6825267a2688c42338 311 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 54 65 3.5E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c11630 a63c47c444240a6825267a2688c42338 311 Pfam PF03466 LysR substrate binding domain 102 308 2.6E-38 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_1c00290 bdb28d6288f1c272c43ecfb5c6c5aa68 134 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 8 19 5.2E-12 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 VAPA_1c00290 bdb28d6288f1c272c43ecfb5c6c5aa68 134 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 43 63 5.2E-12 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 VAPA_1c00290 bdb28d6288f1c272c43ecfb5c6c5aa68 134 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 19 32 5.2E-12 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 VAPA_1c00290 bdb28d6288f1c272c43ecfb5c6c5aa68 134 SMART SM00422 7 76 1.9E-30 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 VAPA_1c00290 bdb28d6288f1c272c43ecfb5c6c5aa68 134 SUPERFAMILY SSF46955 8 132 1.06E-38 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily VAPA_1c00290 bdb28d6288f1c272c43ecfb5c6c5aa68 134 Gene3D G3DSA:1.10.1660.10 5 131 3.8E-37 T 12-10-2018 VAPA_1c00290 bdb28d6288f1c272c43ecfb5c6c5aa68 134 TIGRFAM TIGR02044 CueR: Cu(I)-responsive transcriptional regulator 8 132 5.5E-50 T 12-10-2018 IPR011789 Cu(I)-responsive transcriptional regulator GO:0003677|GO:0003700|GO:0005507|GO:0045893 VAPA_1c00290 bdb28d6288f1c272c43ecfb5c6c5aa68 134 ProSitePatterns PS00552 MerR-type HTH domain signature. 10 32 - T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 VAPA_1c00290 bdb28d6288f1c272c43ecfb5c6c5aa68 134 Pfam PF09278 MerR, DNA binding 51 114 2.4E-20 T 12-10-2018 IPR015358 Transcription regulator MerR, DNA binding VAPA_1c00290 bdb28d6288f1c272c43ecfb5c6c5aa68 134 Pfam PF00376 MerR family regulatory protein 8 45 4.0E-16 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 VAPA_2c11840 0659285f3a8b669ff6c720596d6f225f 397 Pfam PF13378 Enolase C-terminal domain-like 153 368 5.4E-46 T 12-10-2018 IPR029065 Enolase C-terminal domain-like VAPA_2c11840 0659285f3a8b669ff6c720596d6f225f 397 TIGRFAM TIGR02534 mucon_cyclo: muconate and chloromuconate cycloisomerases 7 375 1.2E-133 T 12-10-2018 IPR013370 Muconate/chloromuconate cycloisomerase GO:0018849|GO:0018850|GO:0030145 VAPA_2c11840 0659285f3a8b669ff6c720596d6f225f 397 Gene3D G3DSA:3.30.390.10 14 367 2.0E-113 T 12-10-2018 IPR029017 Enolase-like, N-terminal VAPA_2c11840 0659285f3a8b669ff6c720596d6f225f 397 Gene3D G3DSA:3.20.20.120 123 360 2.0E-113 T 12-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily VAPA_2c11840 0659285f3a8b669ff6c720596d6f225f 397 SUPERFAMILY SSF54826 6 131 5.09E-33 T 12-10-2018 VAPA_2c11840 0659285f3a8b669ff6c720596d6f225f 397 SMART SM00922 148 246 1.8E-13 T 12-10-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal VAPA_2c11840 0659285f3a8b669ff6c720596d6f225f 397 SUPERFAMILY SSF51604 132 373 7.47E-61 T 12-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily VAPA_2c11840 0659285f3a8b669ff6c720596d6f225f 397 ProSitePatterns PS00909 Mandelate racemase / muconate lactonizing enzyme family signature 2. 196 227 - T 12-10-2018 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 VAPA_2c11840 0659285f3a8b669ff6c720596d6f225f 397 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 10 130 2.9E-24 T 12-10-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain VAPA_2c03820 ce2c4e3555b0a85923cf9f73a025e511 108 SUPERFAMILY SSF46785 18 104 5.64E-25 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_2c03820 ce2c4e3555b0a85923cf9f73a025e511 108 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 43 54 1.7E-13 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 VAPA_2c03820 ce2c4e3555b0a85923cf9f73a025e511 108 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 71 86 1.7E-13 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 VAPA_2c03820 ce2c4e3555b0a85923cf9f73a025e511 108 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 24 39 1.7E-13 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 VAPA_2c03820 ce2c4e3555b0a85923cf9f73a025e511 108 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 56 71 1.7E-13 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 VAPA_2c03820 ce2c4e3555b0a85923cf9f73a025e511 108 Gene3D G3DSA:1.10.10.10 11 108 1.3E-26 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_2c03820 ce2c4e3555b0a85923cf9f73a025e511 108 SMART SM00418 22 100 2.1E-26 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 VAPA_2c03820 ce2c4e3555b0a85923cf9f73a025e511 108 Pfam PF01022 Bacterial regulatory protein, arsR family 30 74 6.4E-14 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 VAPA_1c36660 b508ed53abd663f190a6c988c5e7649e 263 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 57 262 1.3E-49 T 12-10-2018 IPR011234 Fumarylacetoacetase-like, C-terminal GO:0003824 VAPA_1c36660 b508ed53abd663f190a6c988c5e7649e 263 SUPERFAMILY SSF56529 52 263 4.19E-67 T 12-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 VAPA_1c36660 b508ed53abd663f190a6c988c5e7649e 263 Gene3D G3DSA:3.90.850.10 30 263 4.8E-81 T 12-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 VAPA_1c08910 c610595e4575a62c96174fbe3a0bef4e 249 Pfam PF00005 ABC transporter 21 169 4.8E-34 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c08910 c610595e4575a62c96174fbe3a0bef4e 249 PIRSF PIRSF039085 2 248 9.1E-99 T 12-10-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 VAPA_1c08910 c610595e4575a62c96174fbe3a0bef4e 249 SMART SM00382 30 217 6.3E-16 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c08910 c610595e4575a62c96174fbe3a0bef4e 249 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_1c08910 c610595e4575a62c96174fbe3a0bef4e 249 Gene3D G3DSA:3.40.50.300 2 249 2.0E-70 T 12-10-2018 VAPA_1c08910 c610595e4575a62c96174fbe3a0bef4e 249 SUPERFAMILY SSF52540 5 236 4.97E-72 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c17430 262f16454bf230dd6216265941a3f7a0 261 SUPERFAMILY SSF56219 1 258 9.29E-80 T 12-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily VAPA_1c17430 262f16454bf230dd6216265941a3f7a0 261 TIGRFAM TIGR00195 exoDNase_III: exodeoxyribonuclease III 1 256 1.2E-77 T 12-10-2018 VAPA_1c17430 262f16454bf230dd6216265941a3f7a0 261 Gene3D G3DSA:3.60.10.10 1 259 4.0E-73 T 12-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily VAPA_1c17430 262f16454bf230dd6216265941a3f7a0 261 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 4 250 7.1E-23 T 12-10-2018 IPR005135 Endonuclease/exonuclease/phosphatase VAPA_1c17430 262f16454bf230dd6216265941a3f7a0 261 TIGRFAM TIGR00633 xth: exodeoxyribonuclease III (xth) 1 258 7.1E-74 T 12-10-2018 IPR004808 AP endonuclease 1 GO:0004518|GO:0006281 VAPA_1c17430 262f16454bf230dd6216265941a3f7a0 261 ProSitePatterns PS00728 AP endonucleases family 1 signature 3. 214 225 - T 12-10-2018 IPR020848 AP endonuclease 1, conserved site GO:0003677|GO:0004519|GO:0005622|GO:0006281 Reactome: R-HSA-110357|Reactome: R-HSA-110362|Reactome: R-HSA-110373|Reactome: R-HSA-5651801|Reactome: R-HSA-73930|Reactome: R-HSA-73933 VAPA_1c22950 c8798b2c241d510163154c0a39488343 720 SUPERFAMILY SSF52242 556 715 1.16E-57 T 12-10-2018 IPR036724 Cobalamin-binding domain superfamily GO:0031419|GO:0046872 Reactome: R-HSA-196741 VAPA_1c22950 c8798b2c241d510163154c0a39488343 720 TIGRFAM TIGR00641 acid_CoA_mut_N: methylmalonyl-CoA mutase N-terminal domain 35 556 2.5E-269 T 12-10-2018 IPR006098 Methylmalonyl-CoA mutase, alpha chain, catalytic GO:0004494|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 VAPA_1c22950 c8798b2c241d510163154c0a39488343 720 ProSitePatterns PS00544 Methylmalonyl-CoA mutase signature. 378 403 - T 12-10-2018 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 VAPA_1c22950 c8798b2c241d510163154c0a39488343 720 TIGRFAM TIGR00640 acid_CoA_mut_C: methylmalonyl-CoA mutase C-terminal domain 588 716 5.0E-60 T 12-10-2018 IPR006159 Methylmalonyl-CoA mutase, C-terminal GO:0016853 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 VAPA_1c22950 c8798b2c241d510163154c0a39488343 720 Gene3D G3DSA:3.20.20.240 35 551 3.1E-243 T 12-10-2018 VAPA_1c22950 c8798b2c241d510163154c0a39488343 720 Gene3D G3DSA:3.40.50.280 555 718 1.1E-53 T 12-10-2018 VAPA_1c22950 c8798b2c241d510163154c0a39488343 720 Pfam PF01642 Methylmalonyl-CoA mutase 37 549 8.2E-241 T 12-10-2018 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 VAPA_1c22950 c8798b2c241d510163154c0a39488343 720 Pfam PF02310 B12 binding domain 591 700 5.7E-17 T 12-10-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 VAPA_1c22950 c8798b2c241d510163154c0a39488343 720 SUPERFAMILY SSF51703 8 551 1.84E-225 T 12-10-2018 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 VAPA_1c51740 2b9dc68c6c5784ab3585415bc724b9ca 371 Pfam PF06224 Winged helix DNA-binding domain 32 354 6.6E-78 T 12-10-2018 IPR009351 Protein of unknown function DUF1006 VAPA_2c12760 983a133fc1b723ea5566f8f2a3404112 82 SMART SM00530 14 70 0.0037 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 VAPA_2c12760 983a133fc1b723ea5566f8f2a3404112 82 Pfam PF01381 Helix-turn-helix 18 65 2.7E-7 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 VAPA_2c12760 983a133fc1b723ea5566f8f2a3404112 82 TIGRFAM TIGR02607 antidote_HigA: addiction module antidote protein, HigA family 6 81 4.0E-28 T 12-10-2018 IPR013430 Toxin-antitoxin system, antidote protein, HigA GO:0003677 VAPA_2c12760 983a133fc1b723ea5566f8f2a3404112 82 SUPERFAMILY SSF47413 10 81 8.76E-18 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 VAPA_2c12760 983a133fc1b723ea5566f8f2a3404112 82 Gene3D G3DSA:1.10.260.40 2 82 2.2E-25 T 12-10-2018 VAPA_2c11590 3a4167def94f18556c0c1032074041a8 238 Gene3D G3DSA:3.40.50.300 5 233 2.3E-45 T 12-10-2018 VAPA_2c11590 3a4167def94f18556c0c1032074041a8 238 TIGRFAM TIGR02324 CP_lyasePhnL: phosphonate C-P lyase system protein PhnL 6 230 1.1E-92 T 12-10-2018 IPR012701 Phosphonate C-P lyase system, PhnL KEGG: 00440+2.7.8.37|MetaCyc: PWY-7399|MetaCyc: PWY-7805|MetaCyc: PWY-7807 VAPA_2c11590 3a4167def94f18556c0c1032074041a8 238 ProSitePatterns PS00211 ABC transporters family signature. 158 172 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_2c11590 3a4167def94f18556c0c1032074041a8 238 SUPERFAMILY SSF52540 5 229 7.31E-40 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_2c11590 3a4167def94f18556c0c1032074041a8 238 Pfam PF00005 ABC transporter 29 186 3.2E-25 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_2c11590 3a4167def94f18556c0c1032074041a8 238 SMART SM00382 37 234 3.5E-7 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c37210 819a0b7e02a876a0392d834a8a9a0202 275 Pfam PF09339 IclR helix-turn-helix domain 25 73 2.1E-9 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 VAPA_1c37210 819a0b7e02a876a0392d834a8a9a0202 275 SMART SM00346 21 111 2.0E-8 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 VAPA_1c37210 819a0b7e02a876a0392d834a8a9a0202 275 Gene3D G3DSA:1.10.10.10 15 89 1.1E-12 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c37210 819a0b7e02a876a0392d834a8a9a0202 275 Pfam PF01614 Bacterial transcriptional regulator 139 247 4.1E-7 T 12-10-2018 IPR014757 Transcription regulator IclR, C-terminal VAPA_1c37210 819a0b7e02a876a0392d834a8a9a0202 275 Gene3D G3DSA:3.30.450.40 91 271 1.6E-24 T 12-10-2018 IPR029016 GAF-like domain superfamily VAPA_1c37210 819a0b7e02a876a0392d834a8a9a0202 275 SUPERFAMILY SSF55781 87 269 1.44E-30 T 12-10-2018 VAPA_1c37210 819a0b7e02a876a0392d834a8a9a0202 275 SUPERFAMILY SSF46785 21 95 3.98E-12 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c35830 362c2863a1505b615f9e838f312152be 411 Pfam PF04542 Sigma-70 region 2 18 78 1.8E-6 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 VAPA_1c35830 362c2863a1505b615f9e838f312152be 411 SUPERFAMILY SSF88946 8 76 6.67E-10 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 VAPA_1c35830 362c2863a1505b615f9e838f312152be 411 Gene3D G3DSA:1.10.1740.10 2 76 1.4E-5 T 12-10-2018 VAPA_1c46420 e46d3bbe173bcf781ecb1f2111cac5aa 230 Gene3D G3DSA:1.10.760.10 27 108 2.5E-20 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 VAPA_1c46420 e46d3bbe173bcf781ecb1f2111cac5aa 230 SUPERFAMILY SSF46626 7 108 2.32E-16 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 VAPA_1c46420 e46d3bbe173bcf781ecb1f2111cac5aa 230 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 30 104 8.9E-5 T 12-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 VAPA_1c46420 e46d3bbe173bcf781ecb1f2111cac5aa 230 Gene3D G3DSA:1.10.760.10 136 213 5.4E-14 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 VAPA_1c46420 e46d3bbe173bcf781ecb1f2111cac5aa 230 SUPERFAMILY SSF46626 138 216 5.53E-13 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 VAPA_1c46420 e46d3bbe173bcf781ecb1f2111cac5aa 230 PIRSF PIRSF000005 1 215 1.5E-36 T 12-10-2018 IPR024167 Cytochrome c4-like GO:0005506|GO:0009055|GO:0020037|GO:0042597 VAPA_1c46420 e46d3bbe173bcf781ecb1f2111cac5aa 230 Pfam PF00034 Cytochrome c 138 213 1.5E-5 T 12-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 VAPA_1c47110 5f1f8add7a411468b57826df3b9b4f22 277 Gene3D G3DSA:1.10.10.60 164 273 7.2E-26 T 12-10-2018 VAPA_1c47110 5f1f8add7a411468b57826df3b9b4f22 277 SUPERFAMILY SSF46689 220 268 9.56E-13 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 VAPA_1c47110 5f1f8add7a411468b57826df3b9b4f22 277 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 235 250 9.5E-6 T 12-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 VAPA_1c47110 5f1f8add7a411468b57826df3b9b4f22 277 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 250 266 9.5E-6 T 12-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 VAPA_1c47110 5f1f8add7a411468b57826df3b9b4f22 277 Pfam PF12833 Helix-turn-helix domain 189 267 1.7E-22 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 VAPA_1c47110 5f1f8add7a411468b57826df3b9b4f22 277 SUPERFAMILY SSF52172 5 137 1.28E-30 T 12-10-2018 IPR011006 CheY-like superfamily VAPA_1c47110 5f1f8add7a411468b57826df3b9b4f22 277 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 220 262 - T 12-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 VAPA_1c47110 5f1f8add7a411468b57826df3b9b4f22 277 Pfam PF00072 Response regulator receiver domain 15 125 1.4E-16 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_1c47110 5f1f8add7a411468b57826df3b9b4f22 277 SMART SM00448 12 125 6.6E-22 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_1c47110 5f1f8add7a411468b57826df3b9b4f22 277 SMART SM00342 182 266 3.2E-24 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 VAPA_1c47110 5f1f8add7a411468b57826df3b9b4f22 277 Gene3D G3DSA:3.40.50.2300 4 140 1.2E-25 T 12-10-2018 VAPA_1c47340 f3531e4794210a99d27dd406259bf743 286 Pfam PF00589 Phage integrase family 115 276 1.1E-15 T 12-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 VAPA_1c47340 f3531e4794210a99d27dd406259bf743 286 Gene3D G3DSA:1.10.150.130 2 112 1.7E-21 T 12-10-2018 IPR010998 Integrase/recombinase, N-terminal VAPA_1c47340 f3531e4794210a99d27dd406259bf743 286 Gene3D G3DSA:1.10.443.10 113 285 2.4E-11 T 12-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 VAPA_1c47340 f3531e4794210a99d27dd406259bf743 286 SUPERFAMILY SSF56349 3 286 8.54E-49 T 12-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 VAPA_2c08960 9ea5d96d7b238ec0e866a86e01dd96dd 292 Pfam PF12833 Helix-turn-helix domain 212 290 3.3E-22 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 VAPA_2c08960 9ea5d96d7b238ec0e866a86e01dd96dd 292 Gene3D G3DSA:2.60.120.10 26 128 4.1E-8 T 12-10-2018 IPR014710 RmlC-like jelly roll fold VAPA_2c08960 9ea5d96d7b238ec0e866a86e01dd96dd 292 Gene3D G3DSA:1.10.10.60 187 292 2.4E-21 T 12-10-2018 VAPA_2c08960 9ea5d96d7b238ec0e866a86e01dd96dd 292 SUPERFAMILY SSF51182 63 215 4.33E-14 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily VAPA_2c08960 9ea5d96d7b238ec0e866a86e01dd96dd 292 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 243 284 - T 12-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 VAPA_2c08960 9ea5d96d7b238ec0e866a86e01dd96dd 292 SUPERFAMILY SSF46689 242 290 1.25E-8 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 VAPA_2c08960 9ea5d96d7b238ec0e866a86e01dd96dd 292 Pfam PF02311 AraC-like ligand binding domain 63 120 1.7E-4 T 12-10-2018 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 VAPA_2c08960 9ea5d96d7b238ec0e866a86e01dd96dd 292 SMART SM00342 206 288 7.0E-23 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 VAPA_1c30250 429ae639e027ad14b6a5acc3486377f9 101 SUPERFAMILY SSF46626 25 98 2.1E-17 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 VAPA_1c30250 429ae639e027ad14b6a5acc3486377f9 101 Gene3D G3DSA:1.10.760.10 15 101 4.4E-32 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 VAPA_1c30250 429ae639e027ad14b6a5acc3486377f9 101 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 23 97 1.9E-6 T 12-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 VAPA_1c30250 429ae639e027ad14b6a5acc3486377f9 101 PRINTS PR00606 Class ID cytochrome C signature 77 87 3.8E-22 T 12-10-2018 IPR002324 Cytochrome c, class ID GO:0005506|GO:0009055|GO:0020037 VAPA_1c30250 429ae639e027ad14b6a5acc3486377f9 101 PRINTS PR00606 Class ID cytochrome C signature 89 99 3.8E-22 T 12-10-2018 IPR002324 Cytochrome c, class ID GO:0005506|GO:0009055|GO:0020037 VAPA_1c30250 429ae639e027ad14b6a5acc3486377f9 101 PRINTS PR00606 Class ID cytochrome C signature 62 75 3.8E-22 T 12-10-2018 IPR002324 Cytochrome c, class ID GO:0005506|GO:0009055|GO:0020037 VAPA_1c30250 429ae639e027ad14b6a5acc3486377f9 101 PRINTS PR00606 Class ID cytochrome C signature 39 52 3.8E-22 T 12-10-2018 IPR002324 Cytochrome c, class ID GO:0005506|GO:0009055|GO:0020037 VAPA_1c30250 429ae639e027ad14b6a5acc3486377f9 101 PRINTS PR00606 Class ID cytochrome C signature 24 37 3.8E-22 T 12-10-2018 IPR002324 Cytochrome c, class ID GO:0005506|GO:0009055|GO:0020037 VAPA_1c01480 d99dfed253fd77fbdf01419f34245d9d 275 Pfam PF08406 CbbQ/NirQ/NorQ C-terminal 189 272 2.1E-27 T 12-10-2018 IPR013615 CbbQ/NirQ/NorQ, C-terminal VAPA_1c01480 d99dfed253fd77fbdf01419f34245d9d 275 Gene3D G3DSA:3.40.50.300 28 194 2.2E-31 T 12-10-2018 VAPA_1c01480 d99dfed253fd77fbdf01419f34245d9d 275 SUPERFAMILY SSF52540 35 231 1.66E-32 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c01480 d99dfed253fd77fbdf01419f34245d9d 275 Pfam PF07728 AAA domain (dynein-related subfamily) 42 176 1.1E-32 T 12-10-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 VAPA_1c11220 5f35abc8b9dffd9bbf9671e15679e9b8 734 Pfam PF04185 Phosphoesterase family 46 462 1.1E-110 T 12-10-2018 IPR007312 Phosphoesterase GO:0016788 VAPA_1c11220 5f35abc8b9dffd9bbf9671e15679e9b8 734 Pfam PF05506 Domain of unknown function (DUF756) 533 622 5.0E-25 T 12-10-2018 IPR008475 Bacterial phospholipase C, C-terminal domain GO:0004629|GO:0016042 KEGG: 00562+3.1.4.3|KEGG: 00564+3.1.4.3|KEGG: 00565+3.1.4.3|MetaCyc: PWY-7782|MetaCyc: PWY-7783 VAPA_1c11220 5f35abc8b9dffd9bbf9671e15679e9b8 734 Pfam PF05506 Domain of unknown function (DUF756) 634 716 5.2E-26 T 12-10-2018 IPR008475 Bacterial phospholipase C, C-terminal domain GO:0004629|GO:0016042 KEGG: 00562+3.1.4.3|KEGG: 00564+3.1.4.3|KEGG: 00565+3.1.4.3|MetaCyc: PWY-7782|MetaCyc: PWY-7783 VAPA_1c11220 5f35abc8b9dffd9bbf9671e15679e9b8 734 TIGRFAM TIGR03396 PC_PLC: phospholipase C, phosphocholine-specific 3 730 1.0E-292 T 12-10-2018 IPR017767 Bacterial phospholipase C, phosphocholine-specific GO:0034480 KEGG: 00562+3.1.4.3|KEGG: 00564+3.1.4.3|KEGG: 00565+3.1.4.3|MetaCyc: PWY-7782|MetaCyc: PWY-7783 VAPA_1c11220 5f35abc8b9dffd9bbf9671e15679e9b8 734 Gene3D G3DSA:3.40.720.10 35 220 1.1E-30 T 12-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 VAPA_1c11220 5f35abc8b9dffd9bbf9671e15679e9b8 734 Gene3D G3DSA:3.40.720.10 306 511 1.3E-49 T 12-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 VAPA_1c01140 8597aeaf3f3064b2ba447aca414119d0 628 Gene3D G3DSA:3.30.450.20 244 337 9.5E-17 T 12-10-2018 VAPA_1c01140 8597aeaf3f3064b2ba447aca414119d0 628 Gene3D G3DSA:3.30.70.1230 434 627 2.0E-57 T 12-10-2018 IPR029787 Nucleotide cyclase VAPA_1c01140 8597aeaf3f3064b2ba447aca414119d0 628 Gene3D G3DSA:3.30.450.20 181 243 9.5E-17 T 12-10-2018 VAPA_1c01140 8597aeaf3f3064b2ba447aca414119d0 628 SMART SM00044 408 606 8.5E-21 T 12-10-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 VAPA_1c01140 8597aeaf3f3064b2ba447aca414119d0 628 SUPERFAMILY SSF55073 439 626 2.04E-52 T 12-10-2018 IPR029787 Nucleotide cyclase VAPA_1c01140 8597aeaf3f3064b2ba447aca414119d0 628 Pfam PF00211 Adenylate and Guanylate cyclase catalytic domain 443 623 2.1E-30 T 12-10-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 VAPA_1c01140 8597aeaf3f3064b2ba447aca414119d0 628 Pfam PF02743 Cache domain 73 328 6.3E-16 T 12-10-2018 IPR033479 Double Cache domain 1 VAPA_2c01150 ac6bc3e5fea062ffbd8872041a9102ed 139 Gene3D G3DSA:3.10.129.10 7 138 2.3E-35 T 12-10-2018 VAPA_2c01150 ac6bc3e5fea062ffbd8872041a9102ed 139 SUPERFAMILY SSF54637 8 136 1.44E-29 T 12-10-2018 IPR029069 HotDog domain superfamily VAPA_2c01150 ac6bc3e5fea062ffbd8872041a9102ed 139 Pfam PF03061 Thioesterase superfamily 49 124 1.2E-10 T 12-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 VAPA_2c01150 ac6bc3e5fea062ffbd8872041a9102ed 139 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 18 128 6.7E-17 T 12-10-2018 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-77289 VAPA_1c40390 a3eaa6eaf274155276b3577b3cee2e39 139 Gene3D G3DSA:3.10.129.10 3 139 1.9E-36 T 12-10-2018 VAPA_1c40390 a3eaa6eaf274155276b3577b3cee2e39 139 ProSitePatterns PS01328 4-hydroxybenzoyl-CoA thioesterase family active site. 12 29 - T 12-10-2018 IPR008272 4-hydroxybenzoyl-CoA thioesterase, active site GO:0016787 VAPA_1c40390 a3eaa6eaf274155276b3577b3cee2e39 139 SUPERFAMILY SSF54637 4 138 2.49E-30 T 12-10-2018 IPR029069 HotDog domain superfamily VAPA_1c40390 a3eaa6eaf274155276b3577b3cee2e39 139 Pfam PF13279 Thioesterase-like superfamily 13 135 8.2E-13 T 12-10-2018 VAPA_1c37790 18a65cd2a7834a5ee1d81958c1c8efc6 448 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 11 346 1.2E-53 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 VAPA_1c37790 18a65cd2a7834a5ee1d81958c1c8efc6 448 SUPERFAMILY SSF51905 3 357 1.81E-33 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c37790 18a65cd2a7834a5ee1d81958c1c8efc6 448 Gene3D G3DSA:3.50.50.100 2 438 1.4E-111 T 12-10-2018 VAPA_1c37790 18a65cd2a7834a5ee1d81958c1c8efc6 448 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 164 182 2.3E-8 T 12-10-2018 VAPA_1c37790 18a65cd2a7834a5ee1d81958c1c8efc6 448 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 12 31 2.3E-8 T 12-10-2018 VAPA_1c37790 18a65cd2a7834a5ee1d81958c1c8efc6 448 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 104 122 2.3E-8 T 12-10-2018 VAPA_1c37790 18a65cd2a7834a5ee1d81958c1c8efc6 448 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 315 322 1.4E-7 T 12-10-2018 VAPA_1c37790 18a65cd2a7834a5ee1d81958c1c8efc6 448 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 11 33 1.4E-7 T 12-10-2018 VAPA_1c37790 18a65cd2a7834a5ee1d81958c1c8efc6 448 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 164 189 1.4E-7 T 12-10-2018 VAPA_1c05940 7f97c9becc470fbb4953f8a2cc4dd68e 1199 SUPERFAMILY SSF52540 139 303 6.95E-10 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c05940 7f97c9becc470fbb4953f8a2cc4dd68e 1199 TIGRFAM TIGR03348 VI_IcmF: type VI secretion protein IcmF 15 1197 0.0 T 12-10-2018 IPR017731 Type VI secretion system, IcmF VAPA_1c05940 7f97c9becc470fbb4953f8a2cc4dd68e 1199 Pfam PF06744 Type VI secretion protein IcmF C-terminal 949 1147 8.2E-57 T 12-10-2018 IPR010623 Type VI secretion system IcmF, C-terminal VAPA_1c05940 7f97c9becc470fbb4953f8a2cc4dd68e 1199 Pfam PF14331 ImcF-related N-terminal domain 209 469 3.3E-93 T 12-10-2018 IPR025743 ImcF-related, N-terminal domain VAPA_1c05940 7f97c9becc470fbb4953f8a2cc4dd68e 1199 Pfam PF06761 Intracellular multiplication and human macrophage-killing 521 831 1.0E-84 T 12-10-2018 IPR009612 ImcF-related VAPA_2c03800 54e87386d3dced2eab872aff4dfd0771 224 SUPERFAMILY SSF52172 1 175 4.27E-37 T 12-10-2018 IPR011006 CheY-like superfamily VAPA_2c03800 54e87386d3dced2eab872aff4dfd0771 224 Gene3D G3DSA:1.10.10.10 122 219 4.5E-23 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_2c03800 54e87386d3dced2eab872aff4dfd0771 224 Pfam PF00072 Response regulator receiver domain 4 112 2.8E-21 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_2c03800 54e87386d3dced2eab872aff4dfd0771 224 SMART SM00862 145 217 5.9E-23 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 VAPA_2c03800 54e87386d3dced2eab872aff4dfd0771 224 Pfam PF00486 Transcriptional regulatory protein, C terminal 145 217 5.6E-18 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 VAPA_2c03800 54e87386d3dced2eab872aff4dfd0771 224 Gene3D G3DSA:3.40.50.2300 1 121 3.5E-35 T 12-10-2018 VAPA_2c03800 54e87386d3dced2eab872aff4dfd0771 224 SMART SM00448 1 112 8.2E-36 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_1c14990 4ca58b3f281b26be88360223ed3d7556 130 TIGRFAM TIGR00556 pantethn_trn: phosphopantetheine--protein transferase domain 1 129 5.0E-24 T 12-10-2018 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289 VAPA_1c14990 4ca58b3f281b26be88360223ed3d7556 130 Hamap MF_00101 Holo-[acyl-carrier-protein] synthase [acpS]. 3 129 23.279 T 12-10-2018 IPR002582 Holo-[acyl carrier protein] synthase GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289 VAPA_1c14990 4ca58b3f281b26be88360223ed3d7556 130 TIGRFAM TIGR00516 acpS: holo-[acyl-carrier-protein] synthase 1 129 2.2E-32 T 12-10-2018 IPR002582 Holo-[acyl carrier protein] synthase GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289 VAPA_1c14990 4ca58b3f281b26be88360223ed3d7556 130 ProDom PD004282 TRANSFERASE SYNTHASE HOLO-ACYL-CARRIER-PROTEIN HOLO-ACP 4'-PHOSPHOPANTETHEINYL FATTY ACID METAL-BINDING MAGNESIUM LIPID 8 96 1.0E-34 T 12-10-2018 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289 VAPA_1c14990 4ca58b3f281b26be88360223ed3d7556 130 SUPERFAMILY SSF56214 1 128 7.33E-27 T 12-10-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 VAPA_1c14990 4ca58b3f281b26be88360223ed3d7556 130 Gene3D G3DSA:3.90.470.20 1 129 6.9E-32 T 12-10-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 VAPA_1c14990 4ca58b3f281b26be88360223ed3d7556 130 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 4 123 7.4E-19 T 12-10-2018 IPR008278 4'-phosphopantetheinyl transferase domain GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 VAPA_1c44300 03f2abef076d08355b7f6eb60ae55b70 303 Gene3D G3DSA:3.40.50.150 32 243 5.1E-24 T 12-10-2018 VAPA_1c44300 03f2abef076d08355b7f6eb60ae55b70 303 SUPERFAMILY SSF53335 44 234 1.56E-23 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase VAPA_1c44300 03f2abef076d08355b7f6eb60ae55b70 303 Pfam PF08241 Methyltransferase domain 74 161 8.6E-15 T 12-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 VAPA_2c12060 13e8bc72a70217e98c464d1745d106ff 293 SUPERFAMILY SSF140959 36 292 1.44E-101 T 12-10-2018 IPR037217 Tryptophan/Indoleamine 2,3-dioxygenase-like GO:0019441|GO:0020037|GO:0046872 KEGG: 00380+1.13.11.11|Reactome: R-HSA-71240 VAPA_2c12060 13e8bc72a70217e98c464d1745d106ff 293 Gene3D G3DSA:1.20.58.480 34 293 1.1E-96 T 12-10-2018 VAPA_2c12060 13e8bc72a70217e98c464d1745d106ff 293 TIGRFAM TIGR03036 trp_2_3_diox: tryptophan 2,3-dioxygenase 30 293 7.9E-130 T 12-10-2018 IPR017485 Tryptophan 2,3-dioxygenase, bacterial GO:0004833|GO:0019441 KEGG: 00380+1.13.11.11 VAPA_2c12060 13e8bc72a70217e98c464d1745d106ff 293 Hamap MF_01972 Tryptophan 2,3-dioxygenase [kynA]. 30 293 40.125 T 12-10-2018 IPR004981 Tryptophan 2,3-dioxygenase GO:0004833|GO:0019441|GO:0020037 KEGG: 00380+1.13.11.11|Reactome: R-HSA-71240 VAPA_2c12060 13e8bc72a70217e98c464d1745d106ff 293 Pfam PF03301 Tryptophan 2,3-dioxygenase 25 219 7.0E-46 T 12-10-2018 IPR004981 Tryptophan 2,3-dioxygenase GO:0004833|GO:0019441|GO:0020037 KEGG: 00380+1.13.11.11|Reactome: R-HSA-71240 VAPA_1c18840 fb9c45574ec2a4696e15857d8a43f477 252 TIGRFAM TIGR00087 surE: 5'/3'-nucleotidase SurE 1 235 1.4E-65 T 12-10-2018 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 VAPA_1c18840 fb9c45574ec2a4696e15857d8a43f477 252 Hamap MF_00060 5'/3'-nucleotidase SurE [surE]. 1 252 38.101 T 12-10-2018 IPR030048 Survival protein SurE GO:0008252 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 VAPA_1c18840 fb9c45574ec2a4696e15857d8a43f477 252 Gene3D G3DSA:3.40.1210.10 1 251 5.9E-90 T 12-10-2018 IPR036523 SurE-like phosphatase/nucleotidase superfamily GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 VAPA_1c18840 fb9c45574ec2a4696e15857d8a43f477 252 SUPERFAMILY SSF64167 1 247 4.05E-82 T 12-10-2018 VAPA_1c18840 fb9c45574ec2a4696e15857d8a43f477 252 Pfam PF01975 Survival protein SurE 3 184 1.6E-59 T 12-10-2018 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 VAPA_2c09940 d70c135f2987ce7f2330b994a51286bc 308 Pfam PF03466 LysR substrate binding domain 89 293 9.8E-45 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_2c09940 d70c135f2987ce7f2330b994a51286bc 308 SUPERFAMILY SSF46785 3 110 4.95E-19 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_2c09940 d70c135f2987ce7f2330b994a51286bc 308 Gene3D G3DSA:1.10.10.10 3 88 1.4E-22 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_2c09940 d70c135f2987ce7f2330b994a51286bc 308 Gene3D G3DSA:3.40.190.10 163 265 2.6E-69 T 12-10-2018 VAPA_2c09940 d70c135f2987ce7f2330b994a51286bc 308 Gene3D G3DSA:3.40.190.10 91 290 2.6E-69 T 12-10-2018 VAPA_2c09940 d70c135f2987ce7f2330b994a51286bc 308 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 63 2.6E-14 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_2c09940 d70c135f2987ce7f2330b994a51286bc 308 SUPERFAMILY SSF53850 89 297 1.57E-49 T 12-10-2018 VAPA_1c33580 68b66491ca1df687fc4d0698c414e559 308 SUPERFAMILY SSF46785 5 116 4.9E-19 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c33580 68b66491ca1df687fc4d0698c414e559 308 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 57 6.3E-16 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c33580 68b66491ca1df687fc4d0698c414e559 308 Gene3D G3DSA:3.40.190.10 167 272 8.4E-70 T 12-10-2018 VAPA_1c33580 68b66491ca1df687fc4d0698c414e559 308 Gene3D G3DSA:3.40.190.10 94 295 8.4E-70 T 12-10-2018 VAPA_1c33580 68b66491ca1df687fc4d0698c414e559 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 44 2.7E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c33580 68b66491ca1df687fc4d0698c414e559 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 23 34 2.7E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c33580 68b66491ca1df687fc4d0698c414e559 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 44 55 2.7E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c33580 68b66491ca1df687fc4d0698c414e559 308 SUPERFAMILY SSF53850 94 298 2.71E-37 T 12-10-2018 VAPA_1c33580 68b66491ca1df687fc4d0698c414e559 308 Gene3D G3DSA:1.10.10.10 5 93 1.2E-21 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c33580 68b66491ca1df687fc4d0698c414e559 308 Pfam PF03466 LysR substrate binding domain 93 298 7.9E-38 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_1c40070 f6b7bd121740a5d23fe4b7ee990ca888 365 Pfam PF00962 Adenosine/AMP deaminase 39 356 2.0E-72 T 12-10-2018 IPR001365 Adenosine/AMP deaminase domain GO:0019239 Reactome: R-HSA-74217 VAPA_1c40070 f6b7bd121740a5d23fe4b7ee990ca888 365 SUPERFAMILY SSF51556 34 362 2.32E-89 T 12-10-2018 IPR032466 Metal-dependent hydrolase VAPA_1c40070 f6b7bd121740a5d23fe4b7ee990ca888 365 Gene3D G3DSA:3.20.20.140 30 364 6.0E-107 T 12-10-2018 VAPA_1c40070 f6b7bd121740a5d23fe4b7ee990ca888 365 TIGRFAM TIGR01430 aden_deam: adenosine deaminase 40 358 2.4E-117 T 12-10-2018 IPR006330 Adenosine/adenine deaminase GO:0019239 Reactome: R-HSA-74217 VAPA_1c40070 f6b7bd121740a5d23fe4b7ee990ca888 365 Hamap MF_01962 Adenine deaminase. 35 347 86.449 T 12-10-2018 IPR028892 Adenine deaminase type 2 GO:0000034|GO:0006146 KEGG: 00230+3.5.4.2|MetaCyc: PWY-6610 VAPA_1c45910 15ce4f0c8a8fb557e6fe26319ffd63ad 345 Pfam PF01137 RNA 3'-terminal phosphate cyclase 9 331 3.4E-78 T 12-10-2018 IPR023797 RNA 3'-terminal phosphate cyclase domain VAPA_1c45910 15ce4f0c8a8fb557e6fe26319ffd63ad 345 PIRSF PIRSF005378 1 343 3.6E-94 T 12-10-2018 IPR000228 RNA 3'-terminal phosphate cyclase GO:0006396 VAPA_1c45910 15ce4f0c8a8fb557e6fe26319ffd63ad 345 SUPERFAMILY SSF52913 183 278 3.53E-21 T 12-10-2018 IPR036553 RNA 3'-terminal phosphate cyclase, insert domain superfamily VAPA_1c45910 15ce4f0c8a8fb557e6fe26319ffd63ad 345 Gene3D G3DSA:3.65.10.20 4 328 6.5E-113 T 12-10-2018 IPR037136 RNA 3'-terminal phosphate cyclase domain superfamily VAPA_1c45910 15ce4f0c8a8fb557e6fe26319ffd63ad 345 TIGRFAM TIGR03399 RNA_3prim_cycl: RNA 3'-phosphate cyclase 2 328 1.6E-105 T 12-10-2018 IPR017770 RNA 3'-terminal phosphate cyclase type 1 GO:0003963|GO:0006396 VAPA_1c45910 15ce4f0c8a8fb557e6fe26319ffd63ad 345 Hamap MF_00200 RNA 3'-terminal phosphate cyclase [rtcA]. 1 343 35.892 T 12-10-2018 IPR017770 RNA 3'-terminal phosphate cyclase type 1 GO:0003963|GO:0006396 VAPA_1c45910 15ce4f0c8a8fb557e6fe26319ffd63ad 345 SUPERFAMILY SSF55205 1 180 3.47E-56 T 12-10-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 VAPA_1c45910 15ce4f0c8a8fb557e6fe26319ffd63ad 345 Gene3D G3DSA:3.30.360.20 183 275 6.5E-113 T 12-10-2018 IPR036553 RNA 3'-terminal phosphate cyclase, insert domain superfamily VAPA_1c39120 7bfc38b677ccaf3237b272ae212cb0ca 300 Gene3D G3DSA:3.30.70.1660 65 293 5.9E-92 T 12-10-2018 VAPA_1c39120 7bfc38b677ccaf3237b272ae212cb0ca 300 SMART SM00937 20 130 3.4E-50 T 12-10-2018 IPR005139 Peptide chain release factor GO:0006415 VAPA_1c39120 7bfc38b677ccaf3237b272ae212cb0ca 300 Gene3D G3DSA:1.20.58.410 1 51 2.1E-5 T 12-10-2018 VAPA_1c39120 7bfc38b677ccaf3237b272ae212cb0ca 300 Pfam PF03462 PCRF domain 4 155 4.1E-43 T 12-10-2018 IPR005139 Peptide chain release factor GO:0006415 VAPA_1c39120 7bfc38b677ccaf3237b272ae212cb0ca 300 TIGRFAM TIGR00020 prfB: peptide chain release factor 2 3 298 2.2E-132 T 12-10-2018 IPR004374 Peptide chain release factor 2 GO:0005737|GO:0006415|GO:0016149 VAPA_1c39120 7bfc38b677ccaf3237b272ae212cb0ca 300 Gene3D G3DSA:3.30.160.20 161 256 5.9E-92 T 12-10-2018 VAPA_1c39120 7bfc38b677ccaf3237b272ae212cb0ca 300 Pfam PF00472 RF-1 domain 164 272 2.0E-40 T 12-10-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 VAPA_1c39120 7bfc38b677ccaf3237b272ae212cb0ca 300 SUPERFAMILY SSF75620 3 297 5.1E-118 T 12-10-2018 VAPA_1c39120 7bfc38b677ccaf3237b272ae212cb0ca 300 Hamap MF_00094 Peptide chain release factor 2 [prfB]. 1 300 31.199 T 12-10-2018 IPR004374 Peptide chain release factor 2 GO:0005737|GO:0006415|GO:0016149 VAPA_1c39120 7bfc38b677ccaf3237b272ae212cb0ca 300 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 180 196 - T 12-10-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 VAPA_1c43380 f265fada79a88ca55f5ed5b5df793223 402 Pfam PF00700 Bacterial flagellin C-terminal helical region 322 402 1.2E-4 T 12-10-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 VAPA_1c43380 f265fada79a88ca55f5ed5b5df793223 402 Gene3D G3DSA:1.20.1330.10 40 221 1.5E-48 T 12-10-2018 VAPA_1c43380 f265fada79a88ca55f5ed5b5df793223 402 Gene3D G3DSA:1.20.1330.10 226 349 4.1E-12 T 12-10-2018 VAPA_1c43380 f265fada79a88ca55f5ed5b5df793223 402 TIGRFAM TIGR02550 flagell_flgL: flagellar hook-associated protein 3 2 402 4.1E-89 T 12-10-2018 IPR013384 Flagellar hook-associated protein 3 GO:0009424|GO:0071973 VAPA_1c43380 f265fada79a88ca55f5ed5b5df793223 402 Pfam PF00669 Bacterial flagellin N-terminal helical region 3 139 7.1E-21 T 12-10-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 VAPA_1c43380 f265fada79a88ca55f5ed5b5df793223 402 SUPERFAMILY SSF64518 1 402 2.48E-73 T 12-10-2018 VAPA_1c13510 1def017bca2bf6d09449f05b8be3fdfa 224 ProSitePatterns PS00042 Crp-type HTH domain signature. 177 200 - T 12-10-2018 IPR018335 Transcription regulator HTH, Crp-type, conserved site GO:0003700|GO:0005622|GO:0006355 VAPA_1c13510 1def017bca2bf6d09449f05b8be3fdfa 224 SMART SM00100 15 133 8.6E-24 T 12-10-2018 IPR000595 Cyclic nucleotide-binding domain VAPA_1c13510 1def017bca2bf6d09449f05b8be3fdfa 224 Gene3D G3DSA:1.10.10.10 150 223 2.5E-17 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c13510 1def017bca2bf6d09449f05b8be3fdfa 224 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 175 191 2.6E-5 T 12-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 VAPA_1c13510 1def017bca2bf6d09449f05b8be3fdfa 224 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 191 206 2.6E-5 T 12-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 VAPA_1c13510 1def017bca2bf6d09449f05b8be3fdfa 224 SMART SM00419 167 218 8.3E-10 T 12-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 VAPA_1c13510 1def017bca2bf6d09449f05b8be3fdfa 224 SUPERFAMILY SSF51206 8 148 1.7E-36 T 12-10-2018 IPR018490 Cyclic nucleotide-binding-like VAPA_1c13510 1def017bca2bf6d09449f05b8be3fdfa 224 SUPERFAMILY SSF46785 150 221 3.02E-13 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c13510 1def017bca2bf6d09449f05b8be3fdfa 224 Pfam PF00027 Cyclic nucleotide-binding domain 34 118 2.7E-24 T 12-10-2018 IPR000595 Cyclic nucleotide-binding domain VAPA_1c13510 1def017bca2bf6d09449f05b8be3fdfa 224 Gene3D G3DSA:2.60.120.10 4 147 1.4E-42 T 12-10-2018 IPR014710 RmlC-like jelly roll fold VAPA_1c13510 1def017bca2bf6d09449f05b8be3fdfa 224 Pfam PF13545 Crp-like helix-turn-helix domain 153 217 4.3E-13 T 12-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 VAPA_1c52290 ea348aa3634fe43bd8b7c17d2cbb2bb4 779 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 404 730 1.6E-57 T 12-10-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 VAPA_1c52290 ea348aa3634fe43bd8b7c17d2cbb2bb4 779 Gene3D G3DSA:3.20.20.70 400 754 6.2E-106 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 VAPA_1c52290 ea348aa3634fe43bd8b7c17d2cbb2bb4 779 Gene3D G3DSA:3.30.9.20 43 259 2.2E-123 T 12-10-2018 VAPA_1c52290 ea348aa3634fe43bd8b7c17d2cbb2bb4 779 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 5 27 4.9E-10 T 12-10-2018 VAPA_1c52290 ea348aa3634fe43bd8b7c17d2cbb2bb4 779 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 134 149 4.9E-10 T 12-10-2018 VAPA_1c52290 ea348aa3634fe43bd8b7c17d2cbb2bb4 779 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 293 309 4.9E-10 T 12-10-2018 VAPA_1c52290 ea348aa3634fe43bd8b7c17d2cbb2bb4 779 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 278 293 4.9E-10 T 12-10-2018 VAPA_1c52290 ea348aa3634fe43bd8b7c17d2cbb2bb4 779 SUPERFAMILY SSF51905 5 359 2.88E-38 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c52290 ea348aa3634fe43bd8b7c17d2cbb2bb4 779 SUPERFAMILY SSF51395 399 757 8.46E-108 T 12-10-2018 VAPA_1c52290 ea348aa3634fe43bd8b7c17d2cbb2bb4 779 Gene3D G3DSA:3.50.50.60 6 351 2.2E-123 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c09700 d87034f50a67b6d65178b38d58ab4a71 695 ProSitePatterns PS01011 Folylpolyglutamate synthase signature 1. 303 327 - T 12-10-2018 IPR018109 Folylpolyglutamate synthetase, conserved site GO:0004326|GO:0005524|GO:0009396 Reactome: R-HSA-196757 VAPA_1c09700 d87034f50a67b6d65178b38d58ab4a71 695 Pfam PF02875 Mur ligase family, glutamate ligase domain 535 606 4.2E-7 T 12-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 VAPA_1c09700 d87034f50a67b6d65178b38d58ab4a71 695 SUPERFAMILY SSF53623 300 531 5.76E-47 T 12-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 VAPA_1c09700 d87034f50a67b6d65178b38d58ab4a71 695 Gene3D G3DSA:3.90.190.20 535 670 1.9E-42 T 12-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 VAPA_1c09700 d87034f50a67b6d65178b38d58ab4a71 695 Gene3D G3DSA:3.40.50.720 3 99 3.7E-17 T 12-10-2018 VAPA_1c09700 d87034f50a67b6d65178b38d58ab4a71 695 SUPERFAMILY SSF51984 4 99 4.32E-11 T 12-10-2018 VAPA_1c09700 d87034f50a67b6d65178b38d58ab4a71 695 Gene3D G3DSA:3.40.1190.10 296 533 2.4E-55 T 12-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 VAPA_1c09700 d87034f50a67b6d65178b38d58ab4a71 695 Pfam PF08245 Mur ligase middle domain 305 514 1.7E-28 T 12-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 VAPA_1c09700 d87034f50a67b6d65178b38d58ab4a71 695 SUPERFAMILY SSF53244 533 674 5.49E-43 T 12-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 VAPA_1c09700 d87034f50a67b6d65178b38d58ab4a71 695 Hamap MF_00639 UDP-N-acetylmuramoylalanine--D-glutamate ligase [murD]. 7 674 30.959 T 12-10-2018 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 VAPA_1c09700 d87034f50a67b6d65178b38d58ab4a71 695 TIGRFAM TIGR01087 murD: UDP-N-acetylmuramoylalanine--D-glutamate ligase 300 672 7.2E-94 T 12-10-2018 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 VAPA_1c30850 54e5d8c007b79e78a5793e962a69d383 957 Gene3D G3DSA:3.30.70.20 147 229 1.7E-24 T 12-10-2018 VAPA_1c30850 54e5d8c007b79e78a5793e962a69d383 957 Pfam PF00037 4Fe-4S binding domain 207 224 9.2E-6 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain VAPA_1c30850 54e5d8c007b79e78a5793e962a69d383 957 Pfam PF10588 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region 102 141 2.4E-16 T 12-10-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VAPA_1c30850 54e5d8c007b79e78a5793e962a69d383 957 Gene3D G3DSA:3.40.228.10 375 586 1.4E-169 T 12-10-2018 VAPA_1c30850 54e5d8c007b79e78a5793e962a69d383 957 Gene3D G3DSA:2.40.40.20 811 925 5.5E-36 T 12-10-2018 VAPA_1c30850 54e5d8c007b79e78a5793e962a69d383 957 Pfam PF00384 Molybdopterin oxidoreductase 295 729 5.4E-72 T 12-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VAPA_1c30850 54e5d8c007b79e78a5793e962a69d383 957 TIGRFAM TIGR01591 Fdh-alpha: formate dehydrogenase, alpha subunit 243 922 1.0E-278 T 12-10-2018 IPR006478 Formate dehydrogenase, alpha subunit GO:0008863|GO:0015942|GO:0055114 KEGG: 00630+1.17.1.9|KEGG: 00680+1.17.1.9|MetaCyc: PWY-1881|MetaCyc: PWY-5497|MetaCyc: PWY-6696|MetaCyc: PWY-7985 VAPA_1c30850 54e5d8c007b79e78a5793e962a69d383 957 PIRSF PIRSF036643 16 956 0.0 T 12-10-2018 VAPA_1c30850 54e5d8c007b79e78a5793e962a69d383 957 SUPERFAMILY SSF54292 21 93 7.7E-18 T 12-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 VAPA_1c30850 54e5d8c007b79e78a5793e962a69d383 957 SMART SM00929 102 142 2.7E-18 T 12-10-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VAPA_1c30850 54e5d8c007b79e78a5793e962a69d383 957 Gene3D G3DSA:3.40.50.740 300 773 1.4E-169 T 12-10-2018 VAPA_1c30850 54e5d8c007b79e78a5793e962a69d383 957 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 242 290 9.7E-16 T 12-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VAPA_1c30850 54e5d8c007b79e78a5793e962a69d383 957 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 211 222 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site VAPA_1c30850 54e5d8c007b79e78a5793e962a69d383 957 Gene3D G3DSA:3.10.20.740 21 141 4.6E-38 T 12-10-2018 VAPA_1c30850 54e5d8c007b79e78a5793e962a69d383 957 SMART SM00926 238 292 1.3E-15 T 12-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VAPA_1c30850 54e5d8c007b79e78a5793e962a69d383 957 SUPERFAMILY SSF54862 94 232 1.3E-38 T 12-10-2018 VAPA_1c30850 54e5d8c007b79e78a5793e962a69d383 957 ProSitePatterns PS00932 Prokaryotic molybdopterin oxidoreductases signature 3. 852 879 - T 12-10-2018 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 VAPA_1c30850 54e5d8c007b79e78a5793e962a69d383 957 Gene3D G3DSA:2.20.25.90 240 291 5.6E-17 T 12-10-2018 VAPA_1c30850 54e5d8c007b79e78a5793e962a69d383 957 SUPERFAMILY SSF53706 241 805 1.03E-188 T 12-10-2018 VAPA_1c30850 54e5d8c007b79e78a5793e962a69d383 957 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 19 95 1.2E-23 T 12-10-2018 VAPA_1c30850 54e5d8c007b79e78a5793e962a69d383 957 SUPERFAMILY SSF50692 782 923 1.81E-40 T 12-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily VAPA_1c30850 54e5d8c007b79e78a5793e962a69d383 957 Pfam PF01568 Molydopterin dinucleotide binding domain 814 918 8.3E-29 T 12-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 VAPA_1c01920 103269e467e92ff485934a5fb29990c8 574 Gene3D G3DSA:3.40.1770.10 27 557 6.9E-252 T 12-10-2018 VAPA_1c01920 103269e467e92ff485934a5fb29990c8 574 Pfam PF17391 Urocanase N-terminal domain 22 148 3.6E-61 T 12-10-2018 IPR035400 Urocanase, N-terminal domain KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 VAPA_1c01920 103269e467e92ff485934a5fb29990c8 574 Gene3D G3DSA:3.40.50.10730 152 365 6.9E-252 T 12-10-2018 IPR038364 Urocanase, central domain superfamily KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 VAPA_1c01920 103269e467e92ff485934a5fb29990c8 574 PIRSF PIRSF001423 7 574 8.7E-291 T 12-10-2018 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 VAPA_1c01920 103269e467e92ff485934a5fb29990c8 574 Hamap MF_00577 Urocanate hydratase [hutU]. 4 572 50.013 T 12-10-2018 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 VAPA_1c01920 103269e467e92ff485934a5fb29990c8 574 TIGRFAM TIGR01228 hutU: urocanate hydratase 21 570 3.6E-287 T 12-10-2018 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 VAPA_1c01920 103269e467e92ff485934a5fb29990c8 574 Pfam PF17392 Urocanase C-terminal domain 368 562 1.6E-92 T 12-10-2018 IPR035401 Urocanase, C-terminal domain KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 VAPA_1c01920 103269e467e92ff485934a5fb29990c8 574 Pfam PF01175 Urocanase Rossmann-like domain 151 365 4.1E-81 T 12-10-2018 IPR035085 Urocanase, Rossmann-like domain KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 VAPA_1c01920 103269e467e92ff485934a5fb29990c8 574 SUPERFAMILY SSF111326 15 572 3.92E-256 T 12-10-2018 IPR036190 Urocanase superfamily KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 VAPA_1c01920 103269e467e92ff485934a5fb29990c8 574 ProSitePatterns PS01233 Urocanase signature. 458 473 - T 12-10-2018 IPR023636 Urocanase conserved site GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 VAPA_1c22620 b64bd908504909757d11b1abc6038053 562 Gene3D G3DSA:3.40.50.970 359 535 2.1E-52 T 12-10-2018 VAPA_1c22620 b64bd908504909757d11b1abc6038053 562 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 200 329 1.5E-27 T 12-10-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 VAPA_1c22620 b64bd908504909757d11b1abc6038053 562 SUPERFAMILY SSF52518 6 187 2.19E-45 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold VAPA_1c22620 b64bd908504909757d11b1abc6038053 562 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 7 179 1.3E-44 T 12-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 VAPA_1c22620 b64bd908504909757d11b1abc6038053 562 SUPERFAMILY SSF52467 194 361 2.96E-37 T 12-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily VAPA_1c22620 b64bd908504909757d11b1abc6038053 562 Gene3D G3DSA:3.40.50.970 1 193 3.1E-50 T 12-10-2018 VAPA_1c22620 b64bd908504909757d11b1abc6038053 562 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 388 527 1.2E-36 T 12-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 VAPA_1c22620 b64bd908504909757d11b1abc6038053 562 SUPERFAMILY SSF52518 361 540 1.79E-53 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold VAPA_1c22620 b64bd908504909757d11b1abc6038053 562 Gene3D G3DSA:3.40.50.1220 194 358 3.1E-37 T 12-10-2018 VAPA_1c12590 84685df58f925d28655a883e3dda7fb2 205 Pfam PF00355 Rieske [2Fe-2S] domain 121 187 2.8E-11 T 12-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 VAPA_1c12590 84685df58f925d28655a883e3dda7fb2 205 Gene3D G3DSA:2.102.10.10 47 199 4.6E-47 T 12-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 VAPA_1c12590 84685df58f925d28655a883e3dda7fb2 205 SUPERFAMILY SSF50022 35 198 1.36E-40 T 12-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 VAPA_1c12590 84685df58f925d28655a883e3dda7fb2 205 PRINTS PR00162 Rieske 2Fe-2S subunit signature 126 137 1.9E-7 T 12-10-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 VAPA_1c12590 84685df58f925d28655a883e3dda7fb2 205 PRINTS PR00162 Rieske 2Fe-2S subunit signature 171 183 1.9E-7 T 12-10-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 VAPA_1c12590 84685df58f925d28655a883e3dda7fb2 205 PRINTS PR00162 Rieske 2Fe-2S subunit signature 158 170 1.9E-7 T 12-10-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 VAPA_1c12590 84685df58f925d28655a883e3dda7fb2 205 TIGRFAM TIGR01416 Rieske_proteo: ubiquinol-cytochrome c reductase, iron-sulfur subunit 14 199 2.8E-62 T 12-10-2018 IPR006317 Ubiquinol-cytochrome c reductase, iron-sulphur subunit GO:0008121|GO:0055114 KEGG: 00190+1.10.2.2|MetaCyc: PWY-3781|MetaCyc: PWY-6692|MetaCyc: PWY-7082|MetaCyc: PWY-7279 VAPA_2c02860 c712b3e7e23598a49b0fc11086cd7000 300 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 61 7.1E-15 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_2c02860 c712b3e7e23598a49b0fc11086cd7000 300 Gene3D G3DSA:3.40.190.10 160 258 2.2E-31 T 12-10-2018 VAPA_2c02860 c712b3e7e23598a49b0fc11086cd7000 300 SUPERFAMILY SSF53850 89 288 2.02E-31 T 12-10-2018 VAPA_2c02860 c712b3e7e23598a49b0fc11086cd7000 300 Pfam PF03466 LysR substrate binding domain 87 286 1.9E-32 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_2c02860 c712b3e7e23598a49b0fc11086cd7000 300 SUPERFAMILY SSF46785 1 108 1.41E-19 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_2c02860 c712b3e7e23598a49b0fc11086cd7000 300 Gene3D G3DSA:1.10.10.10 1 89 4.3E-19 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_2c02860 c712b3e7e23598a49b0fc11086cd7000 300 Gene3D G3DSA:3.40.190.10 90 281 2.2E-31 T 12-10-2018 VAPA_1c09760 188ddbde49875dbc3a7caff8dc683527 409 SUPERFAMILY SSF53067 196 374 3.11E-45 T 12-10-2018 VAPA_1c09760 188ddbde49875dbc3a7caff8dc683527 409 Hamap MF_02033 Cell division protein FtsA [ftsA]. 5 409 29.537 T 12-10-2018 IPR020823 Cell division protein FtsA VAPA_1c09760 188ddbde49875dbc3a7caff8dc683527 409 Pfam PF14450 Cell division protein FtsA 10 190 6.4E-9 T 12-10-2018 VAPA_1c09760 188ddbde49875dbc3a7caff8dc683527 409 PIRSF PIRSF003101 1 409 2.9E-140 T 12-10-2018 IPR020823 Cell division protein FtsA VAPA_1c09760 188ddbde49875dbc3a7caff8dc683527 409 Gene3D G3DSA:3.90.640.10 233 298 8.5E-112 T 12-10-2018 VAPA_1c09760 188ddbde49875dbc3a7caff8dc683527 409 SUPERFAMILY SSF53067 7 218 3.37E-57 T 12-10-2018 VAPA_1c09760 188ddbde49875dbc3a7caff8dc683527 409 Pfam PF14450 Cell division protein FtsA 205 372 3.4E-22 T 12-10-2018 VAPA_1c09760 188ddbde49875dbc3a7caff8dc683527 409 SMART SM00842 9 194 2.1E-96 T 12-10-2018 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0051301 VAPA_1c09760 188ddbde49875dbc3a7caff8dc683527 409 Gene3D G3DSA:3.30.1490.110 86 167 8.5E-112 T 12-10-2018 VAPA_1c09760 188ddbde49875dbc3a7caff8dc683527 409 Gene3D G3DSA:3.30.420.40 12 369 8.5E-112 T 12-10-2018 VAPA_1c09760 188ddbde49875dbc3a7caff8dc683527 409 Gene3D G3DSA:3.30.420.40 195 350 8.5E-112 T 12-10-2018 VAPA_1c09760 188ddbde49875dbc3a7caff8dc683527 409 TIGRFAM TIGR01174 ftsA: cell division protein FtsA 8 375 3.8E-139 T 12-10-2018 IPR020823 Cell division protein FtsA VAPA_1c09760 188ddbde49875dbc3a7caff8dc683527 409 Pfam PF02491 SHS2 domain inserted in FTSA 84 160 9.2E-28 T 12-10-2018 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0051301 VAPA_2c04450 2e8cf40e78aad1339f33e4b2ebd0cbb7 290 Pfam PF01553 Acyltransferase 73 217 9.7E-13 T 12-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 VAPA_2c04450 2e8cf40e78aad1339f33e4b2ebd0cbb7 290 SMART SM00563 84 218 1.5E-16 T 12-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 VAPA_2c04450 2e8cf40e78aad1339f33e4b2ebd0cbb7 290 SUPERFAMILY SSF69593 69 278 4.84E-28 T 12-10-2018 VAPA_1c02190 2fe2535952927afde26337d9b99aee05 641 Pfam PF02653 Branched-chain amino acid transport system / permease component 11 289 4.4E-34 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 VAPA_1c02190 2fe2535952927afde26337d9b99aee05 641 Pfam PF02653 Branched-chain amino acid transport system / permease component 349 604 2.5E-40 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 VAPA_2c02570 a42c2534297b42e33cd8b0fe126e3f4a 361 Gene3D G3DSA:3.40.718.10 2 361 1.8E-137 T 12-10-2018 VAPA_2c02570 a42c2534297b42e33cd8b0fe126e3f4a 361 TIGRFAM TIGR02089 TTC: tartrate dehydrogenase 4 359 9.5E-157 T 12-10-2018 IPR011829 Tartrate dehydrogenase GO:0016616|GO:0051287|GO:0055114 KEGG: 00630+1.1.1.93|KEGG: 00650+1.1.1.83 VAPA_2c02570 a42c2534297b42e33cd8b0fe126e3f4a 361 SMART SM01329 6 355 4.9E-164 T 12-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 VAPA_2c02570 a42c2534297b42e33cd8b0fe126e3f4a 361 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 7 354 7.2E-80 T 12-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 VAPA_2c02570 a42c2534297b42e33cd8b0fe126e3f4a 361 SUPERFAMILY SSF53659 4 358 1.53E-108 T 12-10-2018 VAPA_2c02570 a42c2534297b42e33cd8b0fe126e3f4a 361 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 244 263 - T 12-10-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 VAPA_1c51450 ae877a8e1467af82fa519af258bfdac5 505 SUPERFAMILY SSF53167 15 505 1.06E-142 T 12-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 VAPA_1c51450 ae877a8e1467af82fa519af258bfdac5 505 TIGRFAM TIGR01717 AMP-nucleosdse: AMP nucleosidase 17 505 2.6E-193 T 12-10-2018 IPR011271 AMP nucleosidase GO:0008714|GO:0009116|GO:0044209 KEGG: 00230+3.2.2.4|MetaCyc: PWY-6617 VAPA_1c51450 ae877a8e1467af82fa519af258bfdac5 505 Pfam PF10423 Bacterial AMP nucleoside phosphorylase N-terminus 18 176 4.8E-51 T 12-10-2018 IPR018953 AMP nucleoside phosphorylase, N-terminal KEGG: 00230+3.2.2.4|MetaCyc: PWY-6617 VAPA_1c51450 ae877a8e1467af82fa519af258bfdac5 505 Hamap MF_01932 AMP nucleosidase [amn]. 9 505 61.218 T 12-10-2018 IPR011271 AMP nucleosidase GO:0008714|GO:0009116|GO:0044209 KEGG: 00230+3.2.2.4|MetaCyc: PWY-6617 VAPA_1c51450 ae877a8e1467af82fa519af258bfdac5 505 Gene3D G3DSA:3.40.50.1580 182 505 1.4E-98 T 12-10-2018 VAPA_1c51450 ae877a8e1467af82fa519af258bfdac5 505 Gene3D G3DSA:3.30.1730.10 11 181 1.2E-47 T 12-10-2018 IPR037109 AMP nucleoside phosphorylase, N-terminal domain superfamily KEGG: 00230+3.2.2.4|MetaCyc: PWY-6617 VAPA_1c51450 ae877a8e1467af82fa519af258bfdac5 505 Pfam PF01048 Phosphorylase superfamily 292 452 3.8E-11 T 12-10-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 VAPA_1c00240 def933e3fa5f93e3c3da2788287f8970 795 Pfam PF17092 Penicillin-binding protein OB-like domain 334 438 1.6E-21 T 12-10-2018 IPR031376 Penicillin-binding protein, OB-like domain KEGG: 00550+2.4.1.129+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 VAPA_1c00240 def933e3fa5f93e3c3da2788287f8970 795 Pfam PF00905 Penicillin binding protein transpeptidase domain 440 686 1.3E-36 T 12-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 VAPA_1c00240 def933e3fa5f93e3c3da2788287f8970 795 SUPERFAMILY SSF53955 61 269 2.0E-74 T 12-10-2018 IPR023346 Lysozyme-like domain superfamily VAPA_1c00240 def933e3fa5f93e3c3da2788287f8970 795 TIGRFAM TIGR02074 PBP_1a_fam: penicillin-binding protein, 1A family 84 725 3.1E-181 T 12-10-2018 VAPA_1c00240 def933e3fa5f93e3c3da2788287f8970 795 Gene3D G3DSA:3.40.710.10 262 389 1.3E-5 T 12-10-2018 VAPA_1c00240 def933e3fa5f93e3c3da2788287f8970 795 Gene3D G3DSA:1.10.3810.10 68 261 1.0E-75 T 12-10-2018 IPR036950 Penicillin binding protein transglycosylase domain KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 VAPA_1c00240 def933e3fa5f93e3c3da2788287f8970 795 SUPERFAMILY SSF56601 229 749 1.48E-119 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like VAPA_1c00240 def933e3fa5f93e3c3da2788287f8970 795 Pfam PF00912 Transglycosylase 74 248 4.4E-64 T 12-10-2018 IPR001264 Glycosyl transferase, family 51 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 VAPA_1c00240 def933e3fa5f93e3c3da2788287f8970 795 Gene3D G3DSA:3.40.710.10 416 756 2.5E-107 T 12-10-2018 VAPA_1c51830 87fa95ef029ece50fd893882fd60d994 699 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 533 552 4.0E-24 T 12-10-2018 VAPA_1c51830 87fa95ef029ece50fd893882fd60d994 699 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 159 173 4.0E-24 T 12-10-2018 VAPA_1c51830 87fa95ef029ece50fd893882fd60d994 699 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 480 490 4.0E-24 T 12-10-2018 VAPA_1c51830 87fa95ef029ece50fd893882fd60d994 699 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 556 568 4.0E-24 T 12-10-2018 VAPA_1c51830 87fa95ef029ece50fd893882fd60d994 699 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 316 330 4.0E-24 T 12-10-2018 VAPA_1c51830 87fa95ef029ece50fd893882fd60d994 699 TIGRFAM TIGR01497 kdpB: K+-transporting ATPase, B subunit 9 693 0.0 T 12-10-2018 IPR006391 P-type ATPase, B chain, subfamily IA GO:0005524|GO:0006813|GO:0008556|GO:0016021 VAPA_1c51830 87fa95ef029ece50fd893882fd60d994 699 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 77 353 1.6E-31 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 VAPA_1c51830 87fa95ef029ece50fd893882fd60d994 699 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 435 621 3.2E-46 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 VAPA_1c51830 87fa95ef029ece50fd893882fd60d994 699 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 318 324 - T 12-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 VAPA_1c51830 87fa95ef029ece50fd893882fd60d994 699 SUPERFAMILY SSF81660 327 467 6.32E-30 T 12-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 VAPA_1c51830 87fa95ef029ece50fd893882fd60d994 699 Pfam PF00122 E1-E2 ATPase 128 295 8.8E-30 T 12-10-2018 VAPA_1c51830 87fa95ef029ece50fd893882fd60d994 699 Gene3D G3DSA:2.70.150.20 125 217 2.2E-24 T 12-10-2018 VAPA_1c51830 87fa95ef029ece50fd893882fd60d994 699 SUPERFAMILY SSF81653 127 212 1.83E-19 T 12-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 VAPA_1c51830 87fa95ef029ece50fd893882fd60d994 699 SUPERFAMILY SSF56784 314 580 5.96E-40 T 12-10-2018 IPR036412 HAD-like superfamily VAPA_1c51830 87fa95ef029ece50fd893882fd60d994 699 Hamap MF_00285 Potassium-transporting ATPase ATP-binding subunit [kdpB]. 11 697 40.716 T 12-10-2018 IPR006391 P-type ATPase, B chain, subfamily IA GO:0005524|GO:0006813|GO:0008556|GO:0016021 VAPA_1c51830 87fa95ef029ece50fd893882fd60d994 699 SUPERFAMILY SSF81665 33 310 6.67E-13 T 12-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 VAPA_1c51830 87fa95ef029ece50fd893882fd60d994 699 Gene3D G3DSA:3.40.1110.10 327 464 6.2E-42 T 12-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 VAPA_1c51830 87fa95ef029ece50fd893882fd60d994 699 Pfam PF00702 haloacid dehalogenase-like hydrolase 312 547 1.8E-32 T 12-10-2018 VAPA_1c43890 f4c037925b99e78caa6fb7a70e862c77 409 Gene3D G3DSA:3.60.70.12 4 192 4.1E-61 T 12-10-2018 IPR016117 ArgJ-like domain superfamily KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 VAPA_1c43890 f4c037925b99e78caa6fb7a70e862c77 409 Gene3D G3DSA:3.30.2330.10 193 278 7.0E-24 T 12-10-2018 VAPA_1c43890 f4c037925b99e78caa6fb7a70e862c77 409 TIGRFAM TIGR00120 ArgJ: glutamate N-acetyltransferase/amino-acid acetyltransferase 15 409 2.8E-120 T 12-10-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 VAPA_1c43890 f4c037925b99e78caa6fb7a70e862c77 409 Gene3D G3DSA:3.10.20.340 279 409 2.8E-42 T 12-10-2018 VAPA_1c43890 f4c037925b99e78caa6fb7a70e862c77 409 ProDom PD004193 ACETYLTRANSFERASE ORNITHINE ARGININE BIOSYNTHESIS ARGJ GLUTAMATE N-ACETYLTRANSFERASE TRANSFERASE ACYLTRANSFERASE BIFUNCTIONAL 27 407 4.0E-171 T 12-10-2018 VAPA_1c43890 f4c037925b99e78caa6fb7a70e862c77 409 Pfam PF01960 ArgJ family 22 409 3.4E-140 T 12-10-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 VAPA_1c43890 f4c037925b99e78caa6fb7a70e862c77 409 Hamap MF_01106 Arginine biosynthesis bifunctional protein ArgJ [argJ]. 1 409 154.897 T 12-10-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 VAPA_1c43890 f4c037925b99e78caa6fb7a70e862c77 409 SUPERFAMILY SSF56266 16 406 9.81E-135 T 12-10-2018 IPR016117 ArgJ-like domain superfamily KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 VAPA_1c22240 9e0dffc0583aa7f162aafe0e8f10297c 300 SUPERFAMILY SSF46689 250 296 2.78E-10 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 VAPA_1c22240 9e0dffc0583aa7f162aafe0e8f10297c 300 SUPERFAMILY SSF51215 47 174 6.02E-13 T 12-10-2018 IPR037923 Transcription regulator HTH-like VAPA_1c22240 9e0dffc0583aa7f162aafe0e8f10297c 300 Gene3D G3DSA:1.10.10.60 192 299 1.0E-20 T 12-10-2018 VAPA_1c22240 9e0dffc0583aa7f162aafe0e8f10297c 300 Pfam PF02311 AraC-like ligand binding domain 47 151 8.0E-9 T 12-10-2018 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 VAPA_1c22240 9e0dffc0583aa7f162aafe0e8f10297c 300 SMART SM00342 209 293 1.4E-15 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 VAPA_1c22240 9e0dffc0583aa7f162aafe0e8f10297c 300 Pfam PF12833 Helix-turn-helix domain 216 295 8.6E-20 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 VAPA_1c06690 c1eda41746de310d386995715d32d94e 269 Gene3D G3DSA:3.40.830.10 1 260 7.1E-86 T 12-10-2018 VAPA_1c06690 c1eda41746de310d386995715d32d94e 269 Pfam PF02900 Catalytic LigB subunit of aromatic ring-opening dioxygenase 5 260 4.5E-44 T 12-10-2018 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 VAPA_1c06690 c1eda41746de310d386995715d32d94e 269 SUPERFAMILY SSF53213 3 260 1.23E-82 T 12-10-2018 VAPA_1c06690 c1eda41746de310d386995715d32d94e 269 PIRSF PIRSF006157 1 261 1.6E-78 T 12-10-2018 IPR014436 Extradiol aromatic ring-opening dioxygenase, DODA-type GO:0008270|GO:0016701|GO:0055114 VAPA_1c43600 af0a2aa8bb50446863882f20ea3f79cb 255 SUPERFAMILY SSF46785 145 208 9.33E-9 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c43600 af0a2aa8bb50446863882f20ea3f79cb 255 Pfam PF00027 Cyclic nucleotide-binding domain 25 114 5.4E-11 T 12-10-2018 IPR000595 Cyclic nucleotide-binding domain VAPA_1c43600 af0a2aa8bb50446863882f20ea3f79cb 255 Gene3D G3DSA:1.10.10.10 149 210 2.0E-8 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c43600 af0a2aa8bb50446863882f20ea3f79cb 255 SUPERFAMILY SSF51206 5 139 3.54E-17 T 12-10-2018 IPR018490 Cyclic nucleotide-binding-like VAPA_1c43600 af0a2aa8bb50446863882f20ea3f79cb 255 Gene3D G3DSA:2.60.120.10 3 148 2.3E-19 T 12-10-2018 IPR014710 RmlC-like jelly roll fold VAPA_1c43600 af0a2aa8bb50446863882f20ea3f79cb 255 SMART SM00100 6 129 5.1E-8 T 12-10-2018 IPR000595 Cyclic nucleotide-binding domain VAPA_1c43600 af0a2aa8bb50446863882f20ea3f79cb 255 Pfam PF13545 Crp-like helix-turn-helix domain 145 202 1.3E-8 T 12-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 VAPA_1c43600 af0a2aa8bb50446863882f20ea3f79cb 255 SMART SM00419 162 210 0.007 T 12-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 VAPA_2c01520 fff28556f2a3c56f937c06f44f3ac694 230 Gene3D G3DSA:3.40.190.10 14 226 9.1E-25 T 12-10-2018 VAPA_2c01520 fff28556f2a3c56f937c06f44f3ac694 230 Pfam PF13531 Bacterial extracellular solute-binding protein 10 227 1.7E-31 T 12-10-2018 VAPA_2c01520 fff28556f2a3c56f937c06f44f3ac694 230 SUPERFAMILY SSF53850 10 229 5.85E-36 T 12-10-2018 VAPA_2c01520 fff28556f2a3c56f937c06f44f3ac694 230 Gene3D G3DSA:3.40.190.10 83 190 9.1E-25 T 12-10-2018 VAPA_1c43510 83f2ed264f084926dda433b42e3d01a2 260 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 182 260 1.0E-26 T 12-10-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain VAPA_1c43510 83f2ed264f084926dda433b42e3d01a2 260 TIGRFAM TIGR02490 flgF: flagellar basal-body rod protein FlgF 5 241 1.5E-53 T 12-10-2018 IPR012836 Flagellar basal-body rod FlgF GO:0030694|GO:0071973 VAPA_1c43510 83f2ed264f084926dda433b42e3d01a2 260 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 146 243 2.7E-31 T 12-10-2018 IPR020013 Flagellar hook-basal body protein, FlgE/F/G VAPA_1c43510 83f2ed264f084926dda433b42e3d01a2 260 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 3 136 2.2E-49 T 12-10-2018 IPR020013 Flagellar hook-basal body protein, FlgE/F/G VAPA_1c43510 83f2ed264f084926dda433b42e3d01a2 260 TIGRFAM TIGR02488 flgG_G_neg: flagellar basal-body rod protein FlgG 4 259 4.3E-117 T 12-10-2018 IPR012834 Flagellar basal-body rod FlgG GO:0009426|GO:0071973 VAPA_1c43510 83f2ed264f084926dda433b42e3d01a2 260 Pfam PF00460 Flagella basal body rod protein 5 35 4.6E-13 T 12-10-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 VAPA_1c43510 83f2ed264f084926dda433b42e3d01a2 260 SUPERFAMILY SSF117143 92 222 5.23E-37 T 12-10-2018 IPR037925 Flagellar hook-basal body protein, FlgE/F/G-like VAPA_1c05650 65d71b0b5c53d3c909609a7f57a7cd0a 175 Pfam PF04608 Phosphatidylglycerophosphatase A 19 172 1.6E-45 T 12-10-2018 IPR007686 YutG/PgpA domain GO:0006629|GO:0008962 VAPA_1c05650 65d71b0b5c53d3c909609a7f57a7cd0a 175 SUPERFAMILY SSF101307 14 173 1.06E-29 T 12-10-2018 IPR036681 PgpA-like superfamily GO:0006629|GO:0008962 VAPA_1c05650 65d71b0b5c53d3c909609a7f57a7cd0a 175 PIRSF PIRSF006162 10 175 1.1E-31 T 12-10-2018 IPR026037 Phosphatidylglycerophosphatase A KEGG: 00564+3.1.3.27|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 VAPA_1c20290 a2ab0a553eb64a7372640f3f735f246a 411 PRINTS PR00184 Neisseria sp. porin signature 335 359 2.1E-7 T 12-10-2018 IPR002299 Porin, Neisseria sp. type GO:0015288|GO:0016020|GO:0055085 VAPA_1c20290 a2ab0a553eb64a7372640f3f735f246a 411 PRINTS PR00184 Neisseria sp. porin signature 103 122 2.1E-7 T 12-10-2018 IPR002299 Porin, Neisseria sp. type GO:0015288|GO:0016020|GO:0055085 VAPA_1c20290 a2ab0a553eb64a7372640f3f735f246a 411 PRINTS PR00184 Neisseria sp. porin signature 66 91 2.1E-7 T 12-10-2018 IPR002299 Porin, Neisseria sp. type GO:0015288|GO:0016020|GO:0055085 VAPA_1c20290 a2ab0a553eb64a7372640f3f735f246a 411 Pfam PF13609 Gram-negative porin 11 363 1.4E-53 T 12-10-2018 VAPA_1c20290 a2ab0a553eb64a7372640f3f735f246a 411 SUPERFAMILY SSF56935 20 411 1.16E-55 T 12-10-2018 VAPA_1c20290 a2ab0a553eb64a7372640f3f735f246a 411 Gene3D G3DSA:2.40.160.10 20 411 2.3E-69 T 12-10-2018 IPR023614 Porin domain superfamily VAPA_1c03730 3dbfd2c03b8b71226beb762dd44463ae 356 Gene3D G3DSA:3.40.50.300 2 238 9.9E-76 T 12-10-2018 VAPA_1c03730 3dbfd2c03b8b71226beb762dd44463ae 356 Pfam PF08402 TOBE domain 276 346 7.4E-11 T 12-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 VAPA_1c03730 3dbfd2c03b8b71226beb762dd44463ae 356 SUPERFAMILY SSF50331 238 351 2.25E-12 T 12-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal VAPA_1c03730 3dbfd2c03b8b71226beb762dd44463ae 356 Gene3D G3DSA:2.40.50.100 239 344 2.6E-6 T 12-10-2018 VAPA_1c03730 3dbfd2c03b8b71226beb762dd44463ae 356 SMART SM00382 28 211 1.6E-17 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c03730 3dbfd2c03b8b71226beb762dd44463ae 356 Gene3D G3DSA:2.40.50.140 283 340 2.6E-6 T 12-10-2018 VAPA_1c03730 3dbfd2c03b8b71226beb762dd44463ae 356 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_1c03730 3dbfd2c03b8b71226beb762dd44463ae 356 Pfam PF00005 ABC transporter 21 161 2.0E-34 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c03730 3dbfd2c03b8b71226beb762dd44463ae 356 SUPERFAMILY SSF52540 4 242 6.46E-85 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c26950 6ad5706f8e12d06f9cd5d4939e41b334 308 SUPERFAMILY SSF103025 8 225 2.51E-48 T 12-10-2018 VAPA_1c26950 6ad5706f8e12d06f9cd5d4939e41b334 308 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 209 266 1.3E-5 T 12-10-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 VAPA_1c26950 6ad5706f8e12d06f9cd5d4939e41b334 308 PIRSF PIRSF006487 185 302 0.47 T 12-10-2018 IPR028896 Aminomethyltransferase-like KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 VAPA_1c26950 6ad5706f8e12d06f9cd5d4939e41b334 308 PIRSF PIRSF006487 4 132 7.6E-8 T 12-10-2018 IPR028896 Aminomethyltransferase-like KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 VAPA_1c26950 6ad5706f8e12d06f9cd5d4939e41b334 308 Gene3D G3DSA:3.30.70.1400 16 101 3.2E-22 T 12-10-2018 VAPA_1c26950 6ad5706f8e12d06f9cd5d4939e41b334 308 Gene3D G3DSA:2.40.30.160 179 287 1.1E-28 T 12-10-2018 VAPA_1c26950 6ad5706f8e12d06f9cd5d4939e41b334 308 TIGRFAM TIGR03317 ygfZ_signature: folate-binding protein YgfZ 170 234 4.8E-23 T 12-10-2018 IPR017703 YgfZ/GcvT conserved site VAPA_1c26950 6ad5706f8e12d06f9cd5d4939e41b334 308 Pfam PF01571 Aminomethyltransferase folate-binding domain 8 114 8.5E-11 T 12-10-2018 IPR006222 Aminomethyltransferase, folate-binding domain VAPA_1c31180 c24d77b66f4c38ef23f2c58477932f04 335 Gene3D G3DSA:3.40.50.410 51 274 8.1E-21 T 12-10-2018 IPR036465 von Willebrand factor A-like domain superfamily VAPA_1c25160 857aa07bb438d8927c53537c9325d1bc 249 Hamap MF_00689 Aspartate/glutamate leucyltransferase [bpt]. 10 242 40.336 T 12-10-2018 IPR017138 Aspartate/glutamate leucyltransferase GO:0008914|GO:0071596 MetaCyc: PWY-7802 VAPA_1c25160 857aa07bb438d8927c53537c9325d1bc 249 SUPERFAMILY SSF55729 85 244 8.26E-17 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase VAPA_1c25160 857aa07bb438d8927c53537c9325d1bc 249 Pfam PF04376 Arginine-tRNA-protein transferase, N terminus 20 90 2.6E-18 T 12-10-2018 IPR007471 N-end aminoacyl transferase, N-terminal GO:0004057|GO:0016598 MetaCyc: PWY-7802 VAPA_1c25160 857aa07bb438d8927c53537c9325d1bc 249 PIRSF PIRSF037208 3 249 1.2E-86 T 12-10-2018 IPR017138 Aspartate/glutamate leucyltransferase GO:0008914|GO:0071596 MetaCyc: PWY-7802 VAPA_1c25160 857aa07bb438d8927c53537c9325d1bc 249 Pfam PF04377 Arginine-tRNA-protein transferase, C terminus 110 236 3.4E-35 T 12-10-2018 IPR007472 N-end rule aminoacyl transferase, C-terminal GO:0004057|GO:0016598 MetaCyc: PWY-7802 VAPA_1c22750 72a9be6bac644aeea0cfebc57db22878 294 SUPERFAMILY SSF46785 1 80 4.01E-18 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c22750 72a9be6bac644aeea0cfebc57db22878 294 Gene3D G3DSA:3.40.190.10 165 263 4.7E-64 T 12-10-2018 VAPA_1c22750 72a9be6bac644aeea0cfebc57db22878 294 SUPERFAMILY SSF53850 85 291 1.63E-44 T 12-10-2018 VAPA_1c22750 72a9be6bac644aeea0cfebc57db22878 294 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 61 1.4E-17 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c22750 72a9be6bac644aeea0cfebc57db22878 294 Gene3D G3DSA:3.40.190.10 89 287 4.7E-64 T 12-10-2018 VAPA_1c22750 72a9be6bac644aeea0cfebc57db22878 294 Pfam PF03466 LysR substrate binding domain 88 291 7.9E-24 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_1c22750 72a9be6bac644aeea0cfebc57db22878 294 Gene3D G3DSA:1.10.10.10 1 82 2.2E-26 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c20900 ffc6ff6660e661af7adbb94e2eac16d4 245 Gene3D G3DSA:3.40.50.360 7 245 1.8E-80 T 12-10-2018 IPR029039 Flavoprotein-like superfamily VAPA_1c20900 ffc6ff6660e661af7adbb94e2eac16d4 245 TIGRFAM TIGR02690 resist_ArsH: arsenical resistance protein ArsH 13 231 1.8E-127 T 12-10-2018 IPR014063 Arsenate resistance ArsH VAPA_1c20900 ffc6ff6660e661af7adbb94e2eac16d4 245 Pfam PF03358 NADPH-dependent FMN reductase 40 182 3.1E-28 T 12-10-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 VAPA_1c20900 ffc6ff6660e661af7adbb94e2eac16d4 245 SUPERFAMILY SSF52218 11 233 3.53E-66 T 12-10-2018 IPR029039 Flavoprotein-like superfamily VAPA_1c41850 27f961862b1d79b9e91368f0346c2935 398 Gene3D G3DSA:3.40.50.720 1 397 6.2E-179 T 12-10-2018 VAPA_1c41850 27f961862b1d79b9e91368f0346c2935 398 Pfam PF12242 NAD(P)H binding domain of trans-2-enoyl-CoA reductase 2 80 2.1E-38 T 12-10-2018 IPR010758 Trans-2-enoyl-CoA reductase GO:0016491|GO:0055114 KEGG: 00061+1.3.1.9|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 VAPA_1c41850 27f961862b1d79b9e91368f0346c2935 398 Pfam PF12241 Trans-2-enoyl-CoA reductase catalytic region 82 317 3.6E-106 T 12-10-2018 IPR024910 Trans-2-enoyl-CoA reductase catalytic domain, putative KEGG: 00061+1.3.1.9|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 VAPA_1c41850 27f961862b1d79b9e91368f0346c2935 398 Pfam PF07055 Enoyl reductase FAD binding domain 323 386 3.8E-28 T 12-10-2018 IPR024906 Enoyl reductase FAD binding domain KEGG: 00061+1.3.1.9|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 VAPA_1c41850 27f961862b1d79b9e91368f0346c2935 398 Hamap MF_01838 Trans-2-enoyl-CoA reductase [NADH] [fabV]. 1 392 54.457 T 12-10-2018 IPR010758 Trans-2-enoyl-CoA reductase GO:0016491|GO:0055114 KEGG: 00061+1.3.1.9|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 VAPA_2c04550 0db5f321a00f90a75288d122d00614b8 550 Gene3D G3DSA:1.20.1250.20 12 252 1.2E-73 T 12-10-2018 VAPA_2c04550 0db5f321a00f90a75288d122d00614b8 550 SUPERFAMILY SSF103473 21 542 7.19E-27 T 12-10-2018 IPR036259 MFS transporter superfamily VAPA_2c04550 0db5f321a00f90a75288d122d00614b8 550 Pfam PF07690 Major Facilitator Superfamily 40 181 4.6E-10 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 VAPA_2c04550 0db5f321a00f90a75288d122d00614b8 550 Gene3D G3DSA:1.20.1250.20 320 549 4.2E-63 T 12-10-2018 VAPA_1c38040 902a53fa6dafc524b05263f890c0c5b4 606 Gene3D G3DSA:3.40.50.300 1 212 5.6E-76 T 12-10-2018 VAPA_1c38040 902a53fa6dafc524b05263f890c0c5b4 606 Pfam PF00270 DEAD/DEAH box helicase 25 198 1.8E-50 T 12-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 VAPA_1c38040 902a53fa6dafc524b05263f890c0c5b4 606 Hamap MF_00968 ATP-dependent RNA helicase RhlE [rhlE]. 1 598 48.923 T 12-10-2018 IPR028622 ATP-dependent RNA helicase RhlE GO:0004004|GO:0042255 VAPA_1c38040 902a53fa6dafc524b05263f890c0c5b4 606 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 156 164 - T 12-10-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site VAPA_1c38040 902a53fa6dafc524b05263f890c0c5b4 606 SUPERFAMILY SSF52540 77 362 4.06E-71 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c38040 902a53fa6dafc524b05263f890c0c5b4 606 SMART SM00487 20 225 2.1E-59 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain VAPA_1c38040 902a53fa6dafc524b05263f890c0c5b4 606 Gene3D G3DSA:3.40.50.300 217 388 2.5E-47 T 12-10-2018 VAPA_1c38040 902a53fa6dafc524b05263f890c0c5b4 606 Pfam PF00271 Helicase conserved C-terminal domain 234 342 3.0E-26 T 12-10-2018 IPR001650 Helicase, C-terminal VAPA_1c38040 902a53fa6dafc524b05263f890c0c5b4 606 SMART SM00490 261 342 8.9E-31 T 12-10-2018 IPR001650 Helicase, C-terminal VAPA_2c04770 6595f2eb5a1d02777a374eaad261e7de 877 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 218 367 1.9E-26 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 VAPA_2c04770 6595f2eb5a1d02777a374eaad261e7de 877 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 94 193 1.3E-18 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 VAPA_2c04770 6595f2eb5a1d02777a374eaad261e7de 877 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 576 699 3.1E-34 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 VAPA_2c04770 6595f2eb5a1d02777a374eaad261e7de 877 SMART SM00831 13 87 8.8E-22 T 12-10-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 VAPA_2c04770 6595f2eb5a1d02777a374eaad261e7de 877 Pfam PF00122 E1-E2 ATPase 122 314 6.5E-52 T 12-10-2018 VAPA_2c04770 6595f2eb5a1d02777a374eaad261e7de 877 Gene3D G3DSA:1.20.1110.10 626 868 6.2E-77 T 12-10-2018 VAPA_2c04770 6595f2eb5a1d02777a374eaad261e7de 877 Gene3D G3DSA:2.70.150.10 87 234 1.1E-43 T 12-10-2018 VAPA_2c04770 6595f2eb5a1d02777a374eaad261e7de 877 SUPERFAMILY SSF81653 124 234 1.01E-28 T 12-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 VAPA_2c04770 6595f2eb5a1d02777a374eaad261e7de 877 Pfam PF00702 haloacid dehalogenase-like hydrolase 332 623 1.4E-23 T 12-10-2018 VAPA_2c04770 6595f2eb5a1d02777a374eaad261e7de 877 Gene3D G3DSA:3.40.50.1000 515 625 1.2E-7 T 12-10-2018 IPR023214 HAD superfamily VAPA_2c04770 6595f2eb5a1d02777a374eaad261e7de 877 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 172 186 8.3E-41 T 12-10-2018 VAPA_2c04770 6595f2eb5a1d02777a374eaad261e7de 877 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 609 628 8.3E-41 T 12-10-2018 VAPA_2c04770 6595f2eb5a1d02777a374eaad261e7de 877 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 507 518 8.3E-41 T 12-10-2018 VAPA_2c04770 6595f2eb5a1d02777a374eaad261e7de 877 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 335 349 8.3E-41 T 12-10-2018 VAPA_2c04770 6595f2eb5a1d02777a374eaad261e7de 877 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 633 645 8.3E-41 T 12-10-2018 VAPA_2c04770 6595f2eb5a1d02777a374eaad261e7de 877 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 529 539 8.3E-41 T 12-10-2018 VAPA_2c04770 6595f2eb5a1d02777a374eaad261e7de 877 SUPERFAMILY SSF81665 13 865 9.42E-128 T 12-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 VAPA_2c04770 6595f2eb5a1d02777a374eaad261e7de 877 Pfam PF00689 Cation transporting ATPase, C-terminus 693 862 1.1E-50 T 12-10-2018 IPR006068 Cation-transporting P-type ATPase, C-terminal Reactome: R-HSA-936837 VAPA_2c04770 6595f2eb5a1d02777a374eaad261e7de 877 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 581 597 6.0E-17 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 VAPA_2c04770 6595f2eb5a1d02777a374eaad261e7de 877 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 465 483 6.0E-17 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 VAPA_2c04770 6595f2eb5a1d02777a374eaad261e7de 877 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 641 666 6.0E-17 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 VAPA_2c04770 6595f2eb5a1d02777a374eaad261e7de 877 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 609 625 6.0E-17 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 VAPA_2c04770 6595f2eb5a1d02777a374eaad261e7de 877 Pfam PF00690 Cation transporter/ATPase, N-terminus 15 82 1.7E-17 T 12-10-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 VAPA_2c04770 6595f2eb5a1d02777a374eaad261e7de 877 SUPERFAMILY SSF81660 342 511 2.4E-38 T 12-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 VAPA_2c04770 6595f2eb5a1d02777a374eaad261e7de 877 SUPERFAMILY SSF56784 333 713 7.69E-61 T 12-10-2018 IPR036412 HAD-like superfamily VAPA_2c04770 6595f2eb5a1d02777a374eaad261e7de 877 Gene3D G3DSA:3.40.1110.10 369 514 2.5E-28 T 12-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 VAPA_2c04770 6595f2eb5a1d02777a374eaad261e7de 877 Gene3D G3DSA:1.20.1110.10 235 359 8.8E-39 T 12-10-2018 VAPA_2c04770 6595f2eb5a1d02777a374eaad261e7de 877 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 337 343 - T 12-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 VAPA_1c14130 91753f554b7a97ea4df7640a7c8f549a 289 Gene3D G3DSA:1.10.3720.10 94 285 2.7E-19 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c14130 91753f554b7a97ea4df7640a7c8f549a 289 SUPERFAMILY SSF161098 93 276 7.98E-25 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c14130 91753f554b7a97ea4df7640a7c8f549a 289 TIGRFAM TIGR01183 ntrB: nitrate ABC transporter, permease protein 82 278 6.0E-65 T 12-10-2018 IPR005889 Nitrate transport permease GO:0015112|GO:0015706|GO:0016021 VAPA_1c14130 91753f554b7a97ea4df7640a7c8f549a 289 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 116 278 3.6E-18 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 VAPA_1c04860 608b280d6ef50945656a39d71c4d0687 284 Hamap MF_00102 4-hydroxy-tetrahydrodipicolinate reductase [dapB]. 20 282 34.595 T 12-10-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 VAPA_1c04860 608b280d6ef50945656a39d71c4d0687 284 Gene3D G3DSA:3.30.360.10 144 251 2.0E-101 T 12-10-2018 VAPA_1c04860 608b280d6ef50945656a39d71c4d0687 284 PIRSF PIRSF000161 19 284 2.5E-86 T 12-10-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 VAPA_1c04860 608b280d6ef50945656a39d71c4d0687 284 SUPERFAMILY SSF55347 144 253 3.71E-39 T 12-10-2018 VAPA_1c04860 608b280d6ef50945656a39d71c4d0687 284 ProSitePatterns PS01298 Dihydrodipicolinate reductase signature. 167 184 - T 12-10-2018 IPR022664 Dihydrodipicolinate reductase, conserved site GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 VAPA_1c04860 608b280d6ef50945656a39d71c4d0687 284 Pfam PF01113 Dihydrodipicolinate reductase, N-terminus 21 142 4.1E-37 T 12-10-2018 IPR000846 Dihydrodipicolinate reductase, N-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 VAPA_1c04860 608b280d6ef50945656a39d71c4d0687 284 Gene3D G3DSA:3.40.50.720 21 280 2.0E-101 T 12-10-2018 VAPA_1c04860 608b280d6ef50945656a39d71c4d0687 284 Pfam PF05173 Dihydrodipicolinate reductase, C-terminus 145 281 2.5E-43 T 12-10-2018 IPR022663 Dihydrodipicolinate reductase, C-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 VAPA_1c04860 608b280d6ef50945656a39d71c4d0687 284 TIGRFAM TIGR00036 dapB: 4-hydroxy-tetrahydrodipicolinate reductase 21 282 9.4E-97 T 12-10-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 VAPA_1c04860 608b280d6ef50945656a39d71c4d0687 284 SUPERFAMILY SSF51735 20 283 1.42E-46 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c37910 2e908ba736575fb9edc92e229098e621 304 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 11 69 8.6E-17 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c37910 2e908ba736575fb9edc92e229098e621 304 Gene3D G3DSA:1.10.10.10 9 94 5.9E-21 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c37910 2e908ba736575fb9edc92e229098e621 304 Gene3D G3DSA:3.40.190.10 100 176 1.4E-10 T 12-10-2018 VAPA_1c37910 2e908ba736575fb9edc92e229098e621 304 Pfam PF03466 LysR substrate binding domain 94 302 1.1E-23 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_1c37910 2e908ba736575fb9edc92e229098e621 304 SUPERFAMILY SSF46785 8 92 2.59E-18 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c37910 2e908ba736575fb9edc92e229098e621 304 SUPERFAMILY SSF53850 97 302 9.95E-22 T 12-10-2018 VAPA_1c37910 2e908ba736575fb9edc92e229098e621 304 Gene3D G3DSA:3.40.190.10 177 274 1.4E-10 T 12-10-2018 VAPA_1c10370 600a0b1bbdba4e98031b0051dd63214b 515 Pfam PF00155 Aminotransferase class I and II 134 455 2.8E-25 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 VAPA_1c10370 600a0b1bbdba4e98031b0051dd63214b 515 Gene3D G3DSA:3.40.640.10 149 368 2.2E-94 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 VAPA_1c10370 600a0b1bbdba4e98031b0051dd63214b 515 Pfam PF00392 Bacterial regulatory proteins, gntR family 6 69 1.1E-9 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_1c10370 600a0b1bbdba4e98031b0051dd63214b 515 SMART SM00345 10 69 4.2E-8 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_1c10370 600a0b1bbdba4e98031b0051dd63214b 515 Gene3D G3DSA:3.90.1150.10 111 474 2.2E-94 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 VAPA_1c10370 600a0b1bbdba4e98031b0051dd63214b 515 Gene3D G3DSA:1.10.10.10 3 106 2.5E-15 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c10370 600a0b1bbdba4e98031b0051dd63214b 515 SUPERFAMILY SSF53383 108 477 7.93E-88 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase VAPA_1c10370 600a0b1bbdba4e98031b0051dd63214b 515 SUPERFAMILY SSF46785 2 73 8.18E-16 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c30040 8549dd082b563d63fbcd49468be882a9 469 SUPERFAMILY SSF52317 258 450 2.37E-31 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like VAPA_1c30040 8549dd082b563d63fbcd49468be882a9 469 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 260 442 7.9E-29 T 12-10-2018 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 VAPA_1c30040 8549dd082b563d63fbcd49468be882a9 469 Gene3D G3DSA:3.40.50.300 59 200 1.4E-13 T 12-10-2018 VAPA_1c30040 8549dd082b563d63fbcd49468be882a9 469 Gene3D G3DSA:3.40.50.880 268 447 2.8E-12 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like VAPA_1c30040 8549dd082b563d63fbcd49468be882a9 469 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 23 200 5.5E-17 T 12-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain VAPA_1c30040 8549dd082b563d63fbcd49468be882a9 469 SUPERFAMILY SSF52540 23 207 1.02E-37 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c29450 2a8f8652dc0cc0ed3e6160175c753e62 811 Pfam PF01103 Surface antigen 456 811 4.6E-70 T 12-10-2018 IPR000184 Bacterial surface antigen (D15) GO:0019867 Reactome: R-HSA-1268020|Reactome: R-HSA-8949613 VAPA_1c29450 2a8f8652dc0cc0ed3e6160175c753e62 811 Pfam PF07244 Surface antigen variable number repeat 184 271 1.5E-13 T 12-10-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 VAPA_1c29450 2a8f8652dc0cc0ed3e6160175c753e62 811 Pfam PF07244 Surface antigen variable number repeat 275 347 1.7E-9 T 12-10-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 VAPA_1c29450 2a8f8652dc0cc0ed3e6160175c753e62 811 Pfam PF07244 Surface antigen variable number repeat 33 98 8.6E-5 T 12-10-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 VAPA_1c29450 2a8f8652dc0cc0ed3e6160175c753e62 811 Pfam PF07244 Surface antigen variable number repeat 355 429 5.3E-12 T 12-10-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 VAPA_1c29450 2a8f8652dc0cc0ed3e6160175c753e62 811 Pfam PF07244 Surface antigen variable number repeat 100 180 5.1E-11 T 12-10-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 VAPA_1c29450 2a8f8652dc0cc0ed3e6160175c753e62 811 Gene3D G3DSA:3.10.20.310 356 432 2.9E-23 T 12-10-2018 VAPA_1c29450 2a8f8652dc0cc0ed3e6160175c753e62 811 Hamap MF_01430 Outer membrane protein assembly factor BamA [bamA]. 6 811 24.178 T 12-10-2018 IPR023707 Outer membrane protein assembly factor BamA GO:0071709 VAPA_1c29450 2a8f8652dc0cc0ed3e6160175c753e62 811 PIRSF PIRSF006076 1 811 4.4E-233 T 12-10-2018 IPR023707 Outer membrane protein assembly factor BamA GO:0071709 VAPA_1c29450 2a8f8652dc0cc0ed3e6160175c753e62 811 Gene3D G3DSA:3.10.20.310 276 351 1.3E-14 T 12-10-2018 VAPA_1c29450 2a8f8652dc0cc0ed3e6160175c753e62 811 Gene3D G3DSA:3.10.20.310 26 99 1.7E-20 T 12-10-2018 VAPA_1c29450 2a8f8652dc0cc0ed3e6160175c753e62 811 TIGRFAM TIGR03303 OM_YaeT: outer membrane protein assembly complex, YaeT protein 32 811 2.1E-248 T 12-10-2018 IPR023707 Outer membrane protein assembly factor BamA GO:0071709 VAPA_1c29450 2a8f8652dc0cc0ed3e6160175c753e62 811 Gene3D G3DSA:3.10.20.310 183 274 3.4E-21 T 12-10-2018 VAPA_1c29450 2a8f8652dc0cc0ed3e6160175c753e62 811 Gene3D G3DSA:2.40.160.50 433 811 3.0E-96 T 12-10-2018 VAPA_1c29450 2a8f8652dc0cc0ed3e6160175c753e62 811 Gene3D G3DSA:3.10.20.310 100 180 2.9E-16 T 12-10-2018 VAPA_1c24990 d88691a5a1feaa532b046f39de56cbb9 564 Hamap MF_02090 Glutamine-dependent NAD(+) synthetase [nadE]. 3 557 29.87 T 12-10-2018 IPR014445 Glutamine-dependent NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.5.1|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 VAPA_1c24990 d88691a5a1feaa532b046f39de56cbb9 564 Pfam PF00795 Carbon-nitrogen hydrolase 4 253 6.6E-26 T 12-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 VAPA_1c24990 d88691a5a1feaa532b046f39de56cbb9 564 Gene3D G3DSA:3.40.50.620 275 560 6.4E-120 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold VAPA_1c24990 d88691a5a1feaa532b046f39de56cbb9 564 SUPERFAMILY SSF52402 272 541 1.41E-78 T 12-10-2018 VAPA_1c24990 d88691a5a1feaa532b046f39de56cbb9 564 TIGRFAM TIGR00552 nadE: NAD+ synthetase 285 536 8.6E-62 T 12-10-2018 IPR003694 NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.1.5|Reactome: R-HSA-196807 VAPA_1c24990 d88691a5a1feaa532b046f39de56cbb9 564 Gene3D G3DSA:3.60.110.10 1 258 4.4E-90 T 12-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily VAPA_1c24990 d88691a5a1feaa532b046f39de56cbb9 564 SUPERFAMILY SSF56317 2 251 7.19E-58 T 12-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily VAPA_1c24990 d88691a5a1feaa532b046f39de56cbb9 564 PIRSF PIRSF006630 1 257 1.5E-75 T 12-10-2018 IPR014445 Glutamine-dependent NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.5.1|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 VAPA_1c24990 d88691a5a1feaa532b046f39de56cbb9 564 PIRSF PIRSF006630 261 559 2.6E-120 T 12-10-2018 IPR014445 Glutamine-dependent NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.5.1|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 VAPA_1c24990 d88691a5a1feaa532b046f39de56cbb9 564 Pfam PF02540 NAD synthase 278 532 5.7E-75 T 12-10-2018 IPR022310 NAD/GMP synthase VAPA_2c07380 d072e1264615e8b1cda63a3635f2897b 402 Gene3D G3DSA:3.90.1150.10 28 394 6.8E-130 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 VAPA_2c07380 d072e1264615e8b1cda63a3635f2897b 402 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 238 251 - T 12-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 VAPA_2c07380 d072e1264615e8b1cda63a3635f2897b 402 SUPERFAMILY SSF53383 6 398 1.31E-109 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase VAPA_2c07380 d072e1264615e8b1cda63a3635f2897b 402 Gene3D G3DSA:3.40.640.10 65 288 6.8E-130 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 VAPA_2c07380 d072e1264615e8b1cda63a3635f2897b 402 Pfam PF00155 Aminotransferase class I and II 34 394 3.2E-68 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 VAPA_1c30840 16611c7020137782cefb32332f6eda4c 518 Pfam PF10589 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region 428 509 2.1E-29 T 12-10-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VAPA_1c30840 16611c7020137782cefb32332f6eda4c 518 SUPERFAMILY SSF142984 340 421 2.35E-20 T 12-10-2018 VAPA_1c30840 16611c7020137782cefb32332f6eda4c 518 SUPERFAMILY SSF142019 97 337 1.15E-83 T 12-10-2018 IPR037225 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VAPA_1c30840 16611c7020137782cefb32332f6eda4c 518 ProSitePatterns PS00645 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 2. 439 450 - T 12-10-2018 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VAPA_1c30840 16611c7020137782cefb32332f6eda4c 518 SMART SM00928 426 471 6.9E-18 T 12-10-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VAPA_1c30840 16611c7020137782cefb32332f6eda4c 518 Gene3D G3DSA:3.40.50.11540 150 328 3.2E-70 T 12-10-2018 IPR037225 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VAPA_1c30840 16611c7020137782cefb32332f6eda4c 518 SUPERFAMILY SSF140490 423 508 3.79E-27 T 12-10-2018 IPR037207 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VAPA_1c30840 16611c7020137782cefb32332f6eda4c 518 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 146 316 1.1E-44 T 12-10-2018 IPR011538 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VAPA_1c30840 16611c7020137782cefb32332f6eda4c 518 Gene3D G3DSA:3.10.20.600 329 423 1.5E-22 T 12-10-2018 VAPA_1c30840 16611c7020137782cefb32332f6eda4c 518 Gene3D G3DSA:1.20.1440.230 424 516 1.6E-24 T 12-10-2018 IPR037207 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VAPA_1c14900 f5724b37ac4bf1a5294d901fdcc79385 356 PIRSF PIRSF005427 11 356 2.5E-74 T 12-10-2018 IPR005588 MucB/RseB VAPA_1c14900 f5724b37ac4bf1a5294d901fdcc79385 356 Pfam PF17188 MucB/RseB C-terminal domain 248 352 2.6E-22 T 12-10-2018 IPR033436 MucB/RseB, C-terminal VAPA_1c14900 f5724b37ac4bf1a5294d901fdcc79385 356 Gene3D G3DSA:2.50.20.10 52 232 2.2E-50 T 12-10-2018 VAPA_1c14900 f5724b37ac4bf1a5294d901fdcc79385 356 Gene3D G3DSA:3.30.200.100 250 355 1.2E-9 T 12-10-2018 IPR038484 MucB/RseB, C-terminal domain superfamily VAPA_1c14900 f5724b37ac4bf1a5294d901fdcc79385 356 Pfam PF03888 MucB/RseB N-terminal domain 54 230 4.1E-53 T 12-10-2018 IPR033434 MucB/RseB, N-terminal VAPA_1c06360 4293185fdce1e27f2a95f5743bcd2726 360 PIRSF PIRSF020870 1 356 3.4E-173 T 12-10-2018 IPR016779 Radical SAM enzyme, MSMEG0568 VAPA_1c06360 4293185fdce1e27f2a95f5743bcd2726 360 Pfam PF04055 Radical SAM superfamily 125 282 2.7E-13 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 VAPA_1c06360 4293185fdce1e27f2a95f5743bcd2726 360 Gene3D G3DSA:3.20.20.70 103 323 8.0E-14 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 VAPA_1c06360 4293185fdce1e27f2a95f5743bcd2726 360 TIGRFAM TIGR04043 rSAM_MSMEG_0568: radical SAM protein, MSMEG_0568 family 2 355 9.9E-184 T 12-10-2018 IPR016779 Radical SAM enzyme, MSMEG0568 VAPA_1c06360 4293185fdce1e27f2a95f5743bcd2726 360 SUPERFAMILY SSF102114 126 333 9.81E-30 T 12-10-2018 VAPA_1c06360 4293185fdce1e27f2a95f5743bcd2726 360 SMART SM00729 115 324 6.7E-5 T 12-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 VAPA_1c45670 4fe50a5587bfbb75eca024bd9a791e6f 304 SUPERFAMILY SSF53335 70 230 1.71E-13 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase VAPA_1c45670 4fe50a5587bfbb75eca024bd9a791e6f 304 Gene3D G3DSA:3.40.50.150 62 276 1.3E-11 T 12-10-2018 VAPA_1c31050 268d86aafea08585f31d1799817387d3 237 TIGRFAM TIGR03864 PQQ_ABC_ATP: ABC transporter, ATP-binding subunit, PQQ-dependent alcohol dehydrogenase system 2 236 2.3E-96 T 12-10-2018 IPR022467 ABC transporter, ATP-binding subunit, PQQ-dependent alcohol dehydrogenase system VAPA_1c31050 268d86aafea08585f31d1799817387d3 237 SMART SM00382 26 209 1.6E-10 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c31050 268d86aafea08585f31d1799817387d3 237 Gene3D G3DSA:3.40.50.300 1 230 1.1E-66 T 12-10-2018 VAPA_1c31050 268d86aafea08585f31d1799817387d3 237 Pfam PF00005 ABC transporter 17 160 4.2E-31 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c31050 268d86aafea08585f31d1799817387d3 237 SUPERFAMILY SSF52540 2 219 5.74E-61 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c38380 cfadb78c6a8b6be8452db5ef80bf5421 224 SUPERFAMILY SSF50475 20 224 7.5E-63 T 12-10-2018 VAPA_1c38380 cfadb78c6a8b6be8452db5ef80bf5421 224 PIRSF PIRSF000190 7 224 2.5E-76 T 12-10-2018 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0010181 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 VAPA_1c38380 cfadb78c6a8b6be8452db5ef80bf5421 224 Hamap MF_01629 Pyridoxine/pyridoxamine 5'-phosphate oxidase [pdxH]. 23 224 38.095 T 12-10-2018 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0010181 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 VAPA_1c38380 cfadb78c6a8b6be8452db5ef80bf5421 224 Pfam PF10590 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region 184 224 5.0E-18 T 12-10-2018 IPR019576 Pyridoxine 5'-phosphate oxidase, dimerisation, C-terminal KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 VAPA_1c38380 cfadb78c6a8b6be8452db5ef80bf5421 224 ProSitePatterns PS01064 Pyridoxamine 5'-phosphate oxidase signature. 194 207 - T 12-10-2018 IPR019740 Pyridoxamine 5'-phosphate oxidase, conserved site GO:0016638|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 VAPA_1c38380 cfadb78c6a8b6be8452db5ef80bf5421 224 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 48 132 1.7E-22 T 12-10-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 VAPA_1c38380 cfadb78c6a8b6be8452db5ef80bf5421 224 Gene3D G3DSA:2.30.110.10 11 224 1.6E-80 T 12-10-2018 IPR012349 FMN-binding split barrel GO:0048037 VAPA_1c38380 cfadb78c6a8b6be8452db5ef80bf5421 224 TIGRFAM TIGR00558 pdxH: pyridoxamine 5'-phosphate oxidase 15 224 3.3E-83 T 12-10-2018 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0010181 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 VAPA_1c31730 17b88caf1a34c63b9560ba45e6d55337 267 Pfam PF07963 Prokaryotic N-terminal methylation motif 10 35 5.1E-8 T 12-10-2018 IPR012902 Prokaryotic N-terminal methylation site VAPA_1c31730 17b88caf1a34c63b9560ba45e6d55337 267 Pfam PF16074 Type IV Pilus-assembly protein W 168 266 1.8E-14 T 12-10-2018 IPR032092 Type IV Pilus-assembly protein W GO:0043683 VAPA_1c31730 17b88caf1a34c63b9560ba45e6d55337 267 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 13 33 - T 12-10-2018 IPR012902 Prokaryotic N-terminal methylation site VAPA_1c29670 4d313471b788d7c852c66e2a9dff743d 746 Pfam PF13291 ACT domain 671 745 8.9E-15 T 12-10-2018 IPR002912 ACT domain VAPA_1c29670 4d313471b788d7c852c66e2a9dff743d 746 Pfam PF02824 TGS domain 419 477 1.5E-20 T 12-10-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 VAPA_1c29670 4d313471b788d7c852c66e2a9dff743d 746 Gene3D G3DSA:3.30.460.10 219 355 4.7E-44 T 12-10-2018 VAPA_1c29670 4d313471b788d7c852c66e2a9dff743d 746 Gene3D G3DSA:3.30.70.260 671 746 2.1E-15 T 12-10-2018 VAPA_1c29670 4d313471b788d7c852c66e2a9dff743d 746 SUPERFAMILY SSF81271 413 477 1.9E-18 T 12-10-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 VAPA_1c29670 4d313471b788d7c852c66e2a9dff743d 746 TIGRFAM TIGR00691 spoT_relA: RelA/SpoT family protein 50 742 9.6E-163 T 12-10-2018 IPR004811 RelA/SpoT family GO:0015969 VAPA_1c29670 4d313471b788d7c852c66e2a9dff743d 746 SUPERFAMILY SSF109604 32 216 3.11E-40 T 12-10-2018 VAPA_1c29670 4d313471b788d7c852c66e2a9dff743d 746 Pfam PF04607 Region found in RelA / SpoT proteins 261 374 1.6E-34 T 12-10-2018 IPR007685 RelA/SpoT GO:0015969 VAPA_1c29670 4d313471b788d7c852c66e2a9dff743d 746 Gene3D G3DSA:3.10.20.30 413 483 4.9E-28 T 12-10-2018 IPR012675 Beta-grasp domain superfamily VAPA_1c29670 4d313471b788d7c852c66e2a9dff743d 746 Gene3D G3DSA:1.10.3210.10 20 217 4.6E-38 T 12-10-2018 VAPA_1c29670 4d313471b788d7c852c66e2a9dff743d 746 Pfam PF13328 HD domain 41 202 4.6E-47 T 12-10-2018 IPR003607 HD/PDEase domain VAPA_1c29670 4d313471b788d7c852c66e2a9dff743d 746 SMART SM00954 261 375 7.4E-61 T 12-10-2018 IPR007685 RelA/SpoT GO:0015969 VAPA_1c29670 4d313471b788d7c852c66e2a9dff743d 746 SUPERFAMILY SSF55021 671 745 2.94E-14 T 12-10-2018 VAPA_1c29670 4d313471b788d7c852c66e2a9dff743d 746 SUPERFAMILY SSF81301 218 401 6.87E-55 T 12-10-2018 VAPA_1c01800 26ee9bc22c955fd3cda63a6e63b28278 620 Hamap MF_00452 Phosphoenolpyruvate carboxykinase [GTP] [pckG]. 13 619 50.571 T 12-10-2018 IPR008209 Phosphoenolpyruvate carboxykinase, GTP-utilising GO:0004611|GO:0005525|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 VAPA_1c01800 26ee9bc22c955fd3cda63a6e63b28278 620 Pfam PF17297 Phosphoenolpyruvate carboxykinase N-terminal domain 25 244 7.3E-107 T 12-10-2018 IPR035078 Phosphoenolpyruvate carboxykinase, GTP-utilising, N-terminal GO:0004611|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 VAPA_1c01800 26ee9bc22c955fd3cda63a6e63b28278 620 Gene3D G3DSA:2.170.8.10 60 410 1.9E-261 T 12-10-2018 VAPA_1c01800 26ee9bc22c955fd3cda63a6e63b28278 620 Pfam PF00821 Phosphoenolpyruvate carboxykinase C-terminal P-loop domain 248 618 7.2E-166 T 12-10-2018 IPR035077 Phosphoenolpyruvate carboxykinase, GTP-utilising, C-terminal GO:0004611|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 VAPA_1c01800 26ee9bc22c955fd3cda63a6e63b28278 620 Gene3D G3DSA:3.40.449.10 24 247 1.9E-261 T 12-10-2018 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 VAPA_1c01800 26ee9bc22c955fd3cda63a6e63b28278 620 Gene3D G3DSA:3.90.228.20 248 612 1.9E-261 T 12-10-2018 IPR013035 Phosphoenolpyruvate carboxykinase, C-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 VAPA_1c01800 26ee9bc22c955fd3cda63a6e63b28278 620 ProSitePatterns PS00505 Phosphoenolpyruvate carboxykinase (GTP) signature. 272 280 - T 12-10-2018 IPR018091 Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site GO:0004613 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 VAPA_1c01800 26ee9bc22c955fd3cda63a6e63b28278 620 SUPERFAMILY SSF68923 13 247 6.8E-104 T 12-10-2018 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 VAPA_1c01800 26ee9bc22c955fd3cda63a6e63b28278 620 SUPERFAMILY SSF53795 248 618 2.98E-153 T 12-10-2018 VAPA_1c01800 26ee9bc22c955fd3cda63a6e63b28278 620 PIRSF PIRSF001348 2 620 1.7E-285 T 12-10-2018 IPR008209 Phosphoenolpyruvate carboxykinase, GTP-utilising GO:0004611|GO:0005525|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 VAPA_1c26730 e775122e31e8ec4ceff605cdcb769c74 505 SUPERFAMILY SSF48179 290 503 2.11E-58 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 VAPA_1c26730 e775122e31e8ec4ceff605cdcb769c74 505 SUPERFAMILY SSF51735 4 288 1.5E-93 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c26730 e775122e31e8ec4ceff605cdcb769c74 505 Gene3D G3DSA:3.40.50.720 2 288 1.8E-103 T 12-10-2018 VAPA_1c26730 e775122e31e8ec4ceff605cdcb769c74 505 Pfam PF01232 Mannitol dehydrogenase Rossmann domain 29 194 4.2E-29 T 12-10-2018 IPR013131 Mannitol dehydrogenase, N-terminal GO:0016491|GO:0055114 VAPA_1c26730 e775122e31e8ec4ceff605cdcb769c74 505 Pfam PF08125 Mannitol dehydrogenase C-terminal domain 223 448 4.6E-76 T 12-10-2018 IPR013118 Mannitol dehydrogenase, C-terminal GO:0016491|GO:0050662|GO:0055114 VAPA_1c26730 e775122e31e8ec4ceff605cdcb769c74 505 PRINTS PR00084 Mannitol dehydrogenase signature 30 40 2.7E-14 T 12-10-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 VAPA_1c26730 e775122e31e8ec4ceff605cdcb769c74 505 PRINTS PR00084 Mannitol dehydrogenase signature 255 270 2.7E-14 T 12-10-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 VAPA_1c26730 e775122e31e8ec4ceff605cdcb769c74 505 PRINTS PR00084 Mannitol dehydrogenase signature 225 238 2.7E-14 T 12-10-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 VAPA_1c26730 e775122e31e8ec4ceff605cdcb769c74 505 PRINTS PR00084 Mannitol dehydrogenase signature 186 199 2.7E-14 T 12-10-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 VAPA_1c26730 e775122e31e8ec4ceff605cdcb769c74 505 Gene3D G3DSA:1.10.1040.10 289 505 9.5E-72 T 12-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 VAPA_1c53390 4b357908f92c723002a7f69550bbec47 258 SUPERFAMILY SSF48008 97 233 3.14E-27 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal VAPA_1c53390 4b357908f92c723002a7f69550bbec47 258 Pfam PF00392 Bacterial regulatory proteins, gntR family 14 77 2.4E-22 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_1c53390 4b357908f92c723002a7f69550bbec47 258 SMART SM00345 18 77 3.7E-23 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_1c53390 4b357908f92c723002a7f69550bbec47 258 Gene3D G3DSA:1.10.10.10 11 81 4.6E-24 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c53390 4b357908f92c723002a7f69550bbec47 258 SUPERFAMILY SSF46785 9 89 5.72E-22 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c53390 4b357908f92c723002a7f69550bbec47 258 Gene3D G3DSA:1.20.120.530 99 233 3.7E-28 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal VAPA_1c53390 4b357908f92c723002a7f69550bbec47 258 Pfam PF07729 FCD domain 100 225 8.7E-24 T 12-10-2018 IPR011711 GntR, C-terminal VAPA_1c53390 4b357908f92c723002a7f69550bbec47 258 SMART SM00895 100 226 7.3E-23 T 12-10-2018 IPR011711 GntR, C-terminal VAPA_1c53390 4b357908f92c723002a7f69550bbec47 258 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 37 51 3.6E-9 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_1c53390 4b357908f92c723002a7f69550bbec47 258 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 51 67 3.6E-9 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_2c07880 4c8ff410532d45706b5485cdebe6e923 410 SUPERFAMILY SSF56954 7 400 3.14E-40 T 12-10-2018 VAPA_2c07880 4c8ff410532d45706b5485cdebe6e923 410 Pfam PF02321 Outer membrane efflux protein 234 400 1.3E-7 T 12-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 VAPA_2c07880 4c8ff410532d45706b5485cdebe6e923 410 Pfam PF02321 Outer membrane efflux protein 27 212 9.7E-10 T 12-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 VAPA_2c07880 4c8ff410532d45706b5485cdebe6e923 410 Gene3D G3DSA:1.20.1600.10 21 401 2.4E-31 T 12-10-2018 VAPA_1c21720 00c32dd9eb10ad1c9956393d53cd204c 575 ProSitePatterns PS00211 ABC transporters family signature. 469 483 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_1c21720 00c32dd9eb10ad1c9956393d53cd204c 575 SUPERFAMILY SSF90123 12 323 6.93E-47 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 VAPA_1c21720 00c32dd9eb10ad1c9956393d53cd204c 575 SUPERFAMILY SSF52540 327 556 1.88E-64 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c21720 00c32dd9eb10ad1c9956393d53cd204c 575 Pfam PF00664 ABC transporter transmembrane region 24 283 2.3E-15 T 12-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 VAPA_1c21720 00c32dd9eb10ad1c9956393d53cd204c 575 SMART SM00382 358 551 7.2E-14 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c21720 00c32dd9eb10ad1c9956393d53cd204c 575 Gene3D G3DSA:3.40.50.300 327 568 4.9E-69 T 12-10-2018 VAPA_1c21720 00c32dd9eb10ad1c9956393d53cd204c 575 Pfam PF00005 ABC transporter 349 496 1.4E-31 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c21720 00c32dd9eb10ad1c9956393d53cd204c 575 TIGRFAM TIGR01842 type_I_sec_PrtD: type I secretion system ATPase 19 557 1.3E-200 T 12-10-2018 IPR010128 ATPase, type I secretion system, PrtD GO:0005524|GO:0008565|GO:0016021|GO:0030253|GO:0030256 VAPA_1c21720 00c32dd9eb10ad1c9956393d53cd204c 575 Gene3D G3DSA:1.20.1560.10 10 320 3.5E-41 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 VAPA_1c49870 9c45cd26f40abc0f68945aaa680939cf 279 Gene3D G3DSA:3.30.450.40 111 275 8.8E-29 T 12-10-2018 IPR029016 GAF-like domain superfamily VAPA_1c49870 9c45cd26f40abc0f68945aaa680939cf 279 SUPERFAMILY SSF55781 95 274 1.24E-29 T 12-10-2018 VAPA_1c49870 9c45cd26f40abc0f68945aaa680939cf 279 SMART SM00346 35 124 2.3E-10 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 VAPA_1c49870 9c45cd26f40abc0f68945aaa680939cf 279 Pfam PF01614 Bacterial transcriptional regulator 156 270 6.7E-16 T 12-10-2018 IPR014757 Transcription regulator IclR, C-terminal VAPA_1c49870 9c45cd26f40abc0f68945aaa680939cf 279 Gene3D G3DSA:1.10.10.10 31 104 4.7E-17 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c49870 9c45cd26f40abc0f68945aaa680939cf 279 SUPERFAMILY SSF46785 37 104 1.64E-12 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c49870 9c45cd26f40abc0f68945aaa680939cf 279 Pfam PF09339 IclR helix-turn-helix domain 38 88 3.4E-13 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 VAPA_1c05330 ef583658c6ef6847103e9eca80b26ba1 312 SUPERFAMILY SSF51569 3 279 1.61E-67 T 12-10-2018 VAPA_1c05330 ef583658c6ef6847103e9eca80b26ba1 312 Pfam PF00682 HMGL-like 6 278 1.4E-46 T 12-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 VAPA_1c05330 ef583658c6ef6847103e9eca80b26ba1 312 Gene3D G3DSA:3.20.20.70 1 290 6.4E-105 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 VAPA_2c00300 fb19cbdaf7d62c63ae4b4bef56270579 524 Gene3D G3DSA:3.90.1300.10 16 524 2.1E-123 T 12-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 VAPA_2c00300 fb19cbdaf7d62c63ae4b4bef56270579 524 Pfam PF01425 Amidase 46 504 5.8E-75 T 12-10-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 VAPA_2c00300 fb19cbdaf7d62c63ae4b4bef56270579 524 SUPERFAMILY SSF75304 20 519 2.22E-95 T 12-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 VAPA_2c02310 7d4266ae98ed6dcefddcfb273b6648e9 156 SMART SM00530 22 77 3.0E-6 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 VAPA_2c02310 7d4266ae98ed6dcefddcfb273b6648e9 156 Gene3D G3DSA:1.10.260.40 10 84 1.4E-14 T 12-10-2018 VAPA_2c02310 7d4266ae98ed6dcefddcfb273b6648e9 156 Pfam PF13560 Helix-turn-helix domain 18 77 8.5E-11 T 12-10-2018 VAPA_2c02310 7d4266ae98ed6dcefddcfb273b6648e9 156 SUPERFAMILY SSF47413 13 77 4.56E-11 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 VAPA_1c51580 b9ceb18e8dfecedf000779e14fdf11c7 372 Gene3D G3DSA:3.90.180.10 17 130 3.4E-8 T 12-10-2018 VAPA_1c51580 b9ceb18e8dfecedf000779e14fdf11c7 372 Pfam PF11017 Protein of unknown function (DUF2855) 39 354 1.8E-113 T 12-10-2018 IPR021276 Protein of unknown function DUF2855 VAPA_1c51580 b9ceb18e8dfecedf000779e14fdf11c7 372 SUPERFAMILY SSF50129 14 113 1.28E-5 T 12-10-2018 IPR011032 GroES-like superfamily VAPA_1c51580 b9ceb18e8dfecedf000779e14fdf11c7 372 Gene3D G3DSA:3.40.50.720 150 222 3.4E-8 T 12-10-2018 VAPA_1c32140 5740599758bedcb8c19cb1f59dee9b60 757 SMART SM01217 675 744 2.1E-28 T 12-10-2018 IPR026891 Fibronectin type III-like domain VAPA_1c32140 5740599758bedcb8c19cb1f59dee9b60 757 Pfam PF01915 Glycosyl hydrolase family 3 C-terminal domain 403 638 1.6E-54 T 12-10-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 VAPA_1c32140 5740599758bedcb8c19cb1f59dee9b60 757 Gene3D G3DSA:3.20.20.300 36 386 1.6E-118 T 12-10-2018 IPR036962 Glycoside hydrolase, family 3, N-terminal domain superfamily GO:0004553|GO:0005975 VAPA_1c32140 5740599758bedcb8c19cb1f59dee9b60 757 SUPERFAMILY SSF51445 34 402 5.47E-104 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily VAPA_1c32140 5740599758bedcb8c19cb1f59dee9b60 757 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 48 362 9.1E-72 T 12-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 VAPA_1c32140 5740599758bedcb8c19cb1f59dee9b60 757 ProSitePatterns PS00775 Glycosyl hydrolases family 3 active site. 285 302 - T 12-10-2018 IPR019800 Glycoside hydrolase, family 3, active site GO:0004553|GO:0005975 VAPA_1c32140 5740599758bedcb8c19cb1f59dee9b60 757 Pfam PF14310 Fibronectin type III-like domain 675 743 2.2E-19 T 12-10-2018 IPR026891 Fibronectin type III-like domain VAPA_1c32140 5740599758bedcb8c19cb1f59dee9b60 757 Gene3D G3DSA:3.40.50.1700 389 639 4.0E-74 T 12-10-2018 IPR036881 Glycoside hydrolase family 3 C-terminal domain superfamily GO:0004553|GO:0005975 VAPA_1c32140 5740599758bedcb8c19cb1f59dee9b60 757 PRINTS PR00133 Glycosyl hydrolase family 3 signature 178 194 4.7E-22 T 12-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 VAPA_1c32140 5740599758bedcb8c19cb1f59dee9b60 757 PRINTS PR00133 Glycosyl hydrolase family 3 signature 113 129 4.7E-22 T 12-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 VAPA_1c32140 5740599758bedcb8c19cb1f59dee9b60 757 PRINTS PR00133 Glycosyl hydrolase family 3 signature 285 303 4.7E-22 T 12-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 VAPA_1c32140 5740599758bedcb8c19cb1f59dee9b60 757 PRINTS PR00133 Glycosyl hydrolase family 3 signature 215 231 4.7E-22 T 12-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 VAPA_1c32140 5740599758bedcb8c19cb1f59dee9b60 757 PRINTS PR00133 Glycosyl hydrolase family 3 signature 132 151 4.7E-22 T 12-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 VAPA_1c32140 5740599758bedcb8c19cb1f59dee9b60 757 Gene3D G3DSA:2.60.40.10 641 752 5.8E-30 T 12-10-2018 IPR013783 Immunoglobulin-like fold VAPA_1c32140 5740599758bedcb8c19cb1f59dee9b60 757 SUPERFAMILY SSF52279 403 638 5.1E-49 T 12-10-2018 IPR036881 Glycoside hydrolase family 3 C-terminal domain superfamily GO:0004553|GO:0005975 VAPA_1c10190 caf686731152f4183a2e3afcd30b04f5 462 Pfam PF00158 Sigma-54 interaction domain 142 308 1.2E-70 T 12-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 VAPA_1c10190 caf686731152f4183a2e3afcd30b04f5 462 Gene3D G3DSA:3.40.50.2300 3 133 7.8E-37 T 12-10-2018 VAPA_1c10190 caf686731152f4183a2e3afcd30b04f5 462 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 228 243 - T 12-10-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 VAPA_1c10190 caf686731152f4183a2e3afcd30b04f5 462 SMART SM00448 6 117 8.6E-35 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_1c10190 caf686731152f4183a2e3afcd30b04f5 462 SUPERFAMILY SSF52540 141 385 2.04E-70 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c10190 caf686731152f4183a2e3afcd30b04f5 462 Gene3D G3DSA:1.10.8.60 313 379 2.0E-22 T 12-10-2018 VAPA_1c10190 caf686731152f4183a2e3afcd30b04f5 462 SUPERFAMILY SSF52172 5 186 3.42E-41 T 12-10-2018 IPR011006 CheY-like superfamily VAPA_1c10190 caf686731152f4183a2e3afcd30b04f5 462 Gene3D G3DSA:3.40.50.300 134 312 5.1E-65 T 12-10-2018 VAPA_1c10190 caf686731152f4183a2e3afcd30b04f5 462 Gene3D G3DSA:1.10.10.60 391 444 6.4E-10 T 12-10-2018 VAPA_1c10190 caf686731152f4183a2e3afcd30b04f5 462 SUPERFAMILY SSF46689 394 443 9.86E-8 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 VAPA_1c10190 caf686731152f4183a2e3afcd30b04f5 462 Pfam PF00072 Response regulator receiver domain 9 117 1.7E-27 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_1c10190 caf686731152f4183a2e3afcd30b04f5 462 SMART SM00382 162 305 2.1E-9 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c10190 caf686731152f4183a2e3afcd30b04f5 462 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 355 364 - T 12-10-2018 IPR025944 Sigma-54 interaction domain, conserved site VAPA_1c10190 caf686731152f4183a2e3afcd30b04f5 462 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 166 179 - T 12-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 VAPA_1c52450 781e586747f84007f05f2cb4fae985c9 172 Pfam PF03719 Ribosomal protein S5, C-terminal domain 92 163 2.7E-30 T 12-10-2018 IPR005324 Ribosomal protein S5, C-terminal GO:0003735|GO:0005840|GO:0006412 VAPA_1c52450 781e586747f84007f05f2cb4fae985c9 172 SUPERFAMILY SSF54768 15 81 2.51E-21 T 12-10-2018 VAPA_1c52450 781e586747f84007f05f2cb4fae985c9 172 Pfam PF00333 Ribosomal protein S5, N-terminal domain 17 80 2.5E-25 T 12-10-2018 IPR013810 Ribosomal protein S5, N-terminal GO:0003723|GO:0003735|GO:0005840|GO:0006412 VAPA_1c52450 781e586747f84007f05f2cb4fae985c9 172 SUPERFAMILY SSF54211 85 164 8.85E-27 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold VAPA_1c52450 781e586747f84007f05f2cb4fae985c9 172 ProSitePatterns PS00585 Ribosomal protein S5 signature. 34 66 - T 12-10-2018 IPR018192 Ribosomal protein S5, N-terminal, conserved site VAPA_1c52450 781e586747f84007f05f2cb4fae985c9 172 Gene3D G3DSA:3.30.160.20 7 78 6.2E-27 T 12-10-2018 VAPA_1c52450 781e586747f84007f05f2cb4fae985c9 172 TIGRFAM TIGR01021 rpsE_bact: ribosomal protein uS5 16 169 4.8E-62 T 12-10-2018 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 VAPA_1c52450 781e586747f84007f05f2cb4fae985c9 172 Hamap MF_01307_B 30S ribosomal protein S5 [rpsE]. 1 169 33.347 T 12-10-2018 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 VAPA_1c52450 781e586747f84007f05f2cb4fae985c9 172 Gene3D G3DSA:3.30.230.10 80 172 4.5E-35 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup VAPA_1c26060 d4b85a3484f3b97f6086c9a9aa19d439 344 SMART SM00062 38 268 8.1E-49 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF VAPA_1c26060 d4b85a3484f3b97f6086c9a9aa19d439 344 SUPERFAMILY SSF53850 29 259 1.81E-49 T 12-10-2018 VAPA_1c26060 d4b85a3484f3b97f6086c9a9aa19d439 344 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 39 246 4.3E-32 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF VAPA_1c26060 d4b85a3484f3b97f6086c9a9aa19d439 344 Gene3D G3DSA:3.40.190.10 28 254 5.5E-56 T 12-10-2018 VAPA_1c26060 d4b85a3484f3b97f6086c9a9aa19d439 344 Gene3D G3DSA:3.40.190.10 130 226 5.5E-56 T 12-10-2018 VAPA_1c19670 ffdd50e31cf8b5deef4c9bd53ae4fe7f 67 SUPERFAMILY SSF143034 2 63 1.44E-21 T 12-10-2018 IPR037229 Ribosomal protein L35 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 VAPA_1c19670 ffdd50e31cf8b5deef4c9bd53ae4fe7f 67 Hamap MF_00514 50S ribosomal protein L35 [rpmI]. 1 64 17.315 T 12-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 VAPA_1c19670 ffdd50e31cf8b5deef4c9bd53ae4fe7f 67 Gene3D G3DSA:2.40.50.530 1 64 4.1E-18 T 12-10-2018 VAPA_1c19670 ffdd50e31cf8b5deef4c9bd53ae4fe7f 67 PRINTS PR00064 Ribosomal protein L35 signature 36 54 1.1E-15 T 12-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 VAPA_1c19670 ffdd50e31cf8b5deef4c9bd53ae4fe7f 67 PRINTS PR00064 Ribosomal protein L35 signature 3 20 1.1E-15 T 12-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 VAPA_1c19670 ffdd50e31cf8b5deef4c9bd53ae4fe7f 67 PRINTS PR00064 Ribosomal protein L35 signature 21 35 1.1E-15 T 12-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 VAPA_1c19670 ffdd50e31cf8b5deef4c9bd53ae4fe7f 67 ProSitePatterns PS00936 Ribosomal protein L35 signature. 5 31 - T 12-10-2018 IPR018265 Ribosomal protein L35, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 VAPA_1c19670 ffdd50e31cf8b5deef4c9bd53ae4fe7f 67 Pfam PF01632 Ribosomal protein L35 2 62 5.6E-23 T 12-10-2018 IPR021137 Ribosomal protein L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 VAPA_1c19670 ffdd50e31cf8b5deef4c9bd53ae4fe7f 67 TIGRFAM TIGR00001 rpmI_bact: ribosomal protein bL35 2 63 5.1E-24 T 12-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 VAPA_1c17720 29b02c9bb0b8f13d43630d8f41b48f91 318 Gene3D G3DSA:3.40.190.10 172 272 3.2E-34 T 12-10-2018 VAPA_1c17720 29b02c9bb0b8f13d43630d8f41b48f91 318 Pfam PF03466 LysR substrate binding domain 101 298 1.1E-29 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_1c17720 29b02c9bb0b8f13d43630d8f41b48f91 318 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 11 69 6.6E-20 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c17720 29b02c9bb0b8f13d43630d8f41b48f91 318 SUPERFAMILY SSF46785 7 89 1.41E-19 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c17720 29b02c9bb0b8f13d43630d8f41b48f91 318 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 47 58 2.7E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c17720 29b02c9bb0b8f13d43630d8f41b48f91 318 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 37 47 2.7E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c17720 29b02c9bb0b8f13d43630d8f41b48f91 318 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 26 37 2.7E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c17720 29b02c9bb0b8f13d43630d8f41b48f91 318 SUPERFAMILY SSF53850 100 301 1.36E-30 T 12-10-2018 VAPA_1c17720 29b02c9bb0b8f13d43630d8f41b48f91 318 Gene3D G3DSA:1.10.10.10 6 94 1.7E-22 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c17720 29b02c9bb0b8f13d43630d8f41b48f91 318 Gene3D G3DSA:3.40.190.10 101 280 3.2E-34 T 12-10-2018 VAPA_1c35960 b37ab11850afdde05b30602fe765fe36 399 SUPERFAMILY SSF48208 3 398 1.3E-112 T 12-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 VAPA_1c35960 b37ab11850afdde05b30602fe765fe36 399 Gene3D G3DSA:1.50.10.10 1 399 1.5E-140 T 12-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 VAPA_1c35960 b37ab11850afdde05b30602fe765fe36 399 Pfam PF07221 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) 31 389 1.5E-102 T 12-10-2018 VAPA_1c29820 bfa193f015c2cd1c27603d814d3229e4 215 ProSitePatterns PS00764 Endonuclease III iron-sulfur binding region signature. 187 203 - T 12-10-2018 IPR004035 Endonuclease III, iron-sulphur binding site Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 VAPA_1c29820 bfa193f015c2cd1c27603d814d3229e4 215 Gene3D G3DSA:1.10.1670.10 12 203 6.0E-73 T 12-10-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 VAPA_1c29820 bfa193f015c2cd1c27603d814d3229e4 215 SUPERFAMILY SSF48150 5 206 4.4E-70 T 12-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 VAPA_1c29820 bfa193f015c2cd1c27603d814d3229e4 215 PIRSF PIRSF001435 1 210 2.4E-48 T 12-10-2018 VAPA_1c29820 bfa193f015c2cd1c27603d814d3229e4 215 Gene3D G3DSA:1.10.340.30 21 132 6.0E-73 T 12-10-2018 VAPA_1c29820 bfa193f015c2cd1c27603d814d3229e4 215 ProSitePatterns PS01155 Endonuclease III family signature. 102 131 - T 12-10-2018 IPR004036 Endonuclease III-like, conserved site-2 Reactome: R-HSA-110357 VAPA_1c29820 bfa193f015c2cd1c27603d814d3229e4 215 Hamap MF_00942 Endonuclease III [nth]. 1 209 36.63 T 12-10-2018 IPR005759 Endonuclease III GO:0003906|GO:0006284 VAPA_1c29820 bfa193f015c2cd1c27603d814d3229e4 215 TIGRFAM TIGR01083 nth: endonuclease III 10 194 1.6E-81 T 12-10-2018 IPR005759 Endonuclease III GO:0003906|GO:0006284 VAPA_1c29820 bfa193f015c2cd1c27603d814d3229e4 215 Pfam PF00633 Helix-hairpin-helix motif 100 127 4.9E-10 T 12-10-2018 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 VAPA_1c29820 bfa193f015c2cd1c27603d814d3229e4 215 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 35 168 3.3E-20 T 12-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 VAPA_1c29820 bfa193f015c2cd1c27603d814d3229e4 215 SMART SM00478 38 185 1.7E-61 T 12-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 VAPA_1c01450 4685bb0370b1d80b43fb41f6edf12f23 215 SMART SM01012 144 199 3.9E-13 T 12-10-2018 IPR005561 ANTAR domain GO:0003723 VAPA_1c01450 4685bb0370b1d80b43fb41f6edf12f23 215 Gene3D G3DSA:1.10.10.10 147 204 7.0E-13 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c01450 4685bb0370b1d80b43fb41f6edf12f23 215 PIRSF PIRSF036382 15 206 1.9E-42 T 12-10-2018 IPR008327 Signal transduction response regulator, antiterminator VAPA_1c01450 4685bb0370b1d80b43fb41f6edf12f23 215 Pfam PF03861 ANTAR domain 149 199 1.2E-12 T 12-10-2018 IPR005561 ANTAR domain GO:0003723 VAPA_1c01450 4685bb0370b1d80b43fb41f6edf12f23 215 SUPERFAMILY SSF52172 17 199 6.3E-39 T 12-10-2018 IPR011006 CheY-like superfamily VAPA_1c01450 4685bb0370b1d80b43fb41f6edf12f23 215 Gene3D G3DSA:3.40.50.2300 14 137 1.1E-40 T 12-10-2018 VAPA_1c38120 cdac77f0d4ed3f62a60ae7c0fb4450b9 247 SMART SM00895 97 219 4.2E-23 T 12-10-2018 IPR011711 GntR, C-terminal VAPA_1c38120 cdac77f0d4ed3f62a60ae7c0fb4450b9 247 Gene3D G3DSA:1.10.10.10 3 73 8.8E-15 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c38120 cdac77f0d4ed3f62a60ae7c0fb4450b9 247 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 28 42 1.4E-8 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_1c38120 cdac77f0d4ed3f62a60ae7c0fb4450b9 247 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 42 58 1.4E-8 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_1c38120 cdac77f0d4ed3f62a60ae7c0fb4450b9 247 Gene3D G3DSA:1.20.120.530 95 232 4.6E-29 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal VAPA_1c38120 cdac77f0d4ed3f62a60ae7c0fb4450b9 247 SMART SM00345 9 68 4.1E-13 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_1c38120 cdac77f0d4ed3f62a60ae7c0fb4450b9 247 Pfam PF00392 Bacterial regulatory proteins, gntR family 11 68 3.9E-14 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_1c38120 cdac77f0d4ed3f62a60ae7c0fb4450b9 247 SUPERFAMILY SSF46785 6 72 1.51E-15 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c38120 cdac77f0d4ed3f62a60ae7c0fb4450b9 247 SUPERFAMILY SSF48008 93 227 3.14E-30 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal VAPA_1c38120 cdac77f0d4ed3f62a60ae7c0fb4450b9 247 Pfam PF07729 FCD domain 97 218 3.3E-26 T 12-10-2018 IPR011711 GntR, C-terminal VAPA_1c47250 d34387472a73abc688ac3f6db9525f74 173 Pfam PF01381 Helix-turn-helix 9 48 7.1E-10 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 VAPA_1c47250 d34387472a73abc688ac3f6db9525f74 173 Pfam PF07883 Cupin domain 99 167 1.5E-12 T 12-10-2018 IPR013096 Cupin 2, conserved barrel VAPA_1c47250 d34387472a73abc688ac3f6db9525f74 173 SMART SM00530 1 50 3.6E-4 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 VAPA_1c47250 d34387472a73abc688ac3f6db9525f74 173 SUPERFAMILY SSF47413 5 54 2.62E-11 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 VAPA_1c47250 d34387472a73abc688ac3f6db9525f74 173 SUPERFAMILY SSF51182 43 169 9.37E-24 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily VAPA_1c47250 d34387472a73abc688ac3f6db9525f74 173 Gene3D G3DSA:2.60.120.10 68 169 2.8E-17 T 12-10-2018 IPR014710 RmlC-like jelly roll fold VAPA_1c47250 d34387472a73abc688ac3f6db9525f74 173 Gene3D G3DSA:1.10.260.40 2 59 3.3E-12 T 12-10-2018 VAPA_1c47620 d4f74261f6af4feda8102a8779c56b67 2031 SMART SM01231 1405 1542 3.8E-8 T 12-10-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 VAPA_1c47620 d4f74261f6af4feda8102a8779c56b67 2031 Gene3D G3DSA:3.30.565.10 1541 1727 1.4E-48 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_1c47620 d4f74261f6af4feda8102a8779c56b67 2031 Pfam PF01584 CheW-like domain 1733 1860 4.3E-11 T 12-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 VAPA_1c47620 d4f74261f6af4feda8102a8779c56b67 2031 SMART SM00260 1720 1861 7.8E-5 T 12-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 VAPA_1c47620 d4f74261f6af4feda8102a8779c56b67 2031 SUPERFAMILY SSF52172 1907 2023 2.85E-36 T 12-10-2018 IPR011006 CheY-like superfamily VAPA_1c47620 d4f74261f6af4feda8102a8779c56b67 2031 Pfam PF00072 Response regulator receiver domain 1907 2018 3.0E-26 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_1c47620 d4f74261f6af4feda8102a8779c56b67 2031 SUPERFAMILY SSF47226 1067 1179 4.97E-10 T 12-10-2018 IPR036641 HPT domain superfamily GO:0000160 VAPA_1c47620 d4f74261f6af4feda8102a8779c56b67 2031 SUPERFAMILY SSF47226 456 538 7.65E-5 T 12-10-2018 IPR036641 HPT domain superfamily GO:0000160 VAPA_1c47620 d4f74261f6af4feda8102a8779c56b67 2031 Gene3D G3DSA:1.20.120.160 1066 1198 6.7E-7 T 12-10-2018 IPR036641 HPT domain superfamily GO:0000160 VAPA_1c47620 d4f74261f6af4feda8102a8779c56b67 2031 Gene3D G3DSA:2.40.50.180 1751 1816 5.3E-24 T 12-10-2018 VAPA_1c47620 d4f74261f6af4feda8102a8779c56b67 2031 Gene3D G3DSA:2.30.30.40 1728 1856 5.3E-24 T 12-10-2018 VAPA_1c47620 d4f74261f6af4feda8102a8779c56b67 2031 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 1591 1727 2.8E-13 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase VAPA_1c47620 d4f74261f6af4feda8102a8779c56b67 2031 SMART SM00387 1587 1728 6.1E-17 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase VAPA_1c47620 d4f74261f6af4feda8102a8779c56b67 2031 Gene3D G3DSA:3.40.50.12740 1906 2030 1.2E-38 T 12-10-2018 VAPA_1c47620 d4f74261f6af4feda8102a8779c56b67 2031 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1712 1725 1.5E-10 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c47620 d4f74261f6af4feda8102a8779c56b67 2031 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1672 1682 1.5E-10 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c47620 d4f74261f6af4feda8102a8779c56b67 2031 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1688 1706 1.5E-10 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c47620 d4f74261f6af4feda8102a8779c56b67 2031 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1632 1646 1.5E-10 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c47620 d4f74261f6af4feda8102a8779c56b67 2031 SMART SM00448 1905 2018 2.8E-36 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_1c47620 d4f74261f6af4feda8102a8779c56b67 2031 SUPERFAMILY SSF47226 665 773 6.02E-23 T 12-10-2018 IPR036641 HPT domain superfamily GO:0000160 VAPA_1c47620 d4f74261f6af4feda8102a8779c56b67 2031 Pfam PF01627 Hpt domain 667 760 6.9E-14 T 12-10-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160 VAPA_1c47620 d4f74261f6af4feda8102a8779c56b67 2031 Pfam PF01627 Hpt domain 1068 1156 3.1E-6 T 12-10-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160 VAPA_1c47620 d4f74261f6af4feda8102a8779c56b67 2031 Pfam PF01627 Hpt domain 1230 1321 3.4E-14 T 12-10-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160 VAPA_1c47620 d4f74261f6af4feda8102a8779c56b67 2031 SMART SM00073 663 761 4.1E-10 T 12-10-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160 VAPA_1c47620 d4f74261f6af4feda8102a8779c56b67 2031 SMART SM00073 1219 1330 0.057 T 12-10-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160 VAPA_1c47620 d4f74261f6af4feda8102a8779c56b67 2031 SUPERFAMILY SSF50341 1727 1858 1.7E-20 T 12-10-2018 IPR036061 CheW-like domain superfamily GO:0006935|GO:0007165 VAPA_1c47620 d4f74261f6af4feda8102a8779c56b67 2031 SUPERFAMILY SSF55874 1544 1726 1.28E-32 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_1c47620 d4f74261f6af4feda8102a8779c56b67 2031 Gene3D G3DSA:1.20.120.160 658 786 6.5E-21 T 12-10-2018 IPR036641 HPT domain superfamily GO:0000160 VAPA_1c47620 d4f74261f6af4feda8102a8779c56b67 2031 SUPERFAMILY SSF47226 1227 1343 1.96E-21 T 12-10-2018 IPR036641 HPT domain superfamily GO:0000160 VAPA_1c47620 d4f74261f6af4feda8102a8779c56b67 2031 Gene3D G3DSA:1.20.120.160 1228 1349 3.3E-20 T 12-10-2018 IPR036641 HPT domain superfamily GO:0000160 VAPA_1c51900 3946acba274b3405343bc1557f695087 349 Gene3D G3DSA:3.60.15.10 92 342 2.3E-57 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like VAPA_1c51900 3946acba274b3405343bc1557f695087 349 SMART SM00849 113 297 1.9E-23 T 12-10-2018 IPR001279 Metallo-beta-lactamase VAPA_1c51900 3946acba274b3405343bc1557f695087 349 SUPERFAMILY SSF56281 103 285 6.29E-39 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like VAPA_1c51900 3946acba274b3405343bc1557f695087 349 Pfam PF00753 Metallo-beta-lactamase superfamily 114 240 2.1E-20 T 12-10-2018 IPR001279 Metallo-beta-lactamase VAPA_2c10710 1c16bac9e9995038174286a9e70f6139 285 Gene3D G3DSA:3.90.850.10 73 285 2.4E-76 T 12-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 VAPA_2c10710 1c16bac9e9995038174286a9e70f6139 285 Pfam PF10370 Domain of unknown function (DUF2437) 1 71 2.8E-4 T 12-10-2018 IPR018833 Domain of unknown function DUF2437 VAPA_2c10710 1c16bac9e9995038174286a9e70f6139 285 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 78 282 4.6E-63 T 12-10-2018 IPR011234 Fumarylacetoacetase-like, C-terminal GO:0003824 VAPA_2c10710 1c16bac9e9995038174286a9e70f6139 285 SUPERFAMILY SSF56529 65 283 1.96E-76 T 12-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 VAPA_1c16260 7e618b184ab5aeb152fb2a4eb392f015 229 SMART SM00421 160 219 6.1E-14 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_1c16260 7e618b184ab5aeb152fb2a4eb392f015 229 Pfam PF00072 Response regulator receiver domain 11 122 5.4E-14 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_1c16260 7e618b184ab5aeb152fb2a4eb392f015 229 Pfam PF00196 Bacterial regulatory proteins, luxR family 162 219 9.4E-13 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_1c16260 7e618b184ab5aeb152fb2a4eb392f015 229 SUPERFAMILY SSF52172 8 136 7.68E-17 T 12-10-2018 IPR011006 CheY-like superfamily VAPA_1c16260 7e618b184ab5aeb152fb2a4eb392f015 229 SUPERFAMILY SSF46894 155 224 1.8E-14 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 VAPA_1c16260 7e618b184ab5aeb152fb2a4eb392f015 229 Gene3D G3DSA:3.40.50.12740 9 224 8.3E-43 T 12-10-2018 VAPA_1c16260 7e618b184ab5aeb152fb2a4eb392f015 229 SMART SM00448 9 122 3.2E-11 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_2c06160 386654c74ba2519731f7d6b3f15c90bb 325 Gene3D G3DSA:1.10.3720.10 84 314 2.4E-21 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_2c06160 386654c74ba2519731f7d6b3f15c90bb 325 SUPERFAMILY SSF161098 91 305 6.1E-17 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_2c06160 386654c74ba2519731f7d6b3f15c90bb 325 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 112 319 1.8E-39 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 VAPA_1c24980 8c5dc18080fee05979a7dc0e1fc390e2 393 Gene3D G3DSA:3.40.630.30 187 352 7.3E-11 T 12-10-2018 VAPA_1c24980 8c5dc18080fee05979a7dc0e1fc390e2 393 SUPERFAMILY SSF55729 197 372 4.7E-36 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase VAPA_1c24980 8c5dc18080fee05979a7dc0e1fc390e2 393 Pfam PF04339 Peptidogalycan biosysnthesis/recognition 12 391 3.3E-145 T 12-10-2018 IPR007434 Peptidogalycan biosysnthesis/recognition VAPA_1c51570 5a0516dd1a58614d9732c0d4971ef3e1 141 Gene3D G3DSA:2.20.25.10 1 45 1.4E-17 T 12-10-2018 VAPA_1c51570 5a0516dd1a58614d9732c0d4971ef3e1 141 SUPERFAMILY SSF82784 3 140 1.57E-39 T 12-10-2018 IPR036102 OsmC/Ohr superfamily VAPA_1c51570 5a0516dd1a58614d9732c0d4971ef3e1 141 Pfam PF02566 OsmC-like protein 41 138 4.4E-18 T 12-10-2018 IPR003718 OsmC/Ohr family VAPA_1c51570 5a0516dd1a58614d9732c0d4971ef3e1 141 Gene3D G3DSA:3.30.300.20 46 141 3.1E-31 T 12-10-2018 IPR015946 K homology domain-like, alpha/beta VAPA_1c51570 5a0516dd1a58614d9732c0d4971ef3e1 141 TIGRFAM TIGR03561 organ_hyd_perox: peroxiredoxin, Ohr subfamily 9 139 1.1E-48 T 12-10-2018 IPR019953 Organic hydroperoxide resistance protein famiy GO:0006979 VAPA_1c05230 a5991a6c5aea080184849dbd78f7ccd2 392 Gene3D G3DSA:3.40.47.10 6 275 1.7E-131 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 VAPA_1c05230 a5991a6c5aea080184849dbd78f7ccd2 392 SUPERFAMILY SSF53901 3 268 9.02E-66 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 VAPA_1c05230 a5991a6c5aea080184849dbd78f7ccd2 392 ProSitePatterns PS00737 Thiolases signature 2. 338 354 - T 12-10-2018 IPR020613 Thiolase, conserved site GO:0016747 VAPA_1c05230 a5991a6c5aea080184849dbd78f7ccd2 392 PIRSF PIRSF000429 1 392 7.7E-117 T 12-10-2018 IPR002155 Thiolase GO:0016747 VAPA_1c05230 a5991a6c5aea080184849dbd78f7ccd2 392 Pfam PF00108 Thiolase, N-terminal domain 5 261 3.3E-60 T 12-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 VAPA_1c05230 a5991a6c5aea080184849dbd78f7ccd2 392 SUPERFAMILY SSF53901 270 391 7.29E-41 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 VAPA_1c05230 a5991a6c5aea080184849dbd78f7ccd2 392 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 390 4.6E-123 T 12-10-2018 IPR002155 Thiolase GO:0016747 VAPA_1c05230 a5991a6c5aea080184849dbd78f7ccd2 392 Pfam PF02803 Thiolase, C-terminal domain 270 391 2.5E-42 T 12-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 VAPA_1c05230 a5991a6c5aea080184849dbd78f7ccd2 392 Gene3D G3DSA:3.40.47.10 127 388 1.7E-131 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 VAPA_1c01400 cd502a6f96de00a228f811f26b23c11b 288 Pfam PF00775 Dioxygenase 103 276 1.8E-48 T 12-10-2018 IPR000627 Intradiol ring-cleavage dioxygenase, C-terminal GO:0003824|GO:0006725|GO:0008199|GO:0055114 VAPA_1c01400 cd502a6f96de00a228f811f26b23c11b 288 Pfam PF04444 Catechol dioxygenase N terminus 23 95 7.7E-23 T 12-10-2018 IPR007535 Catechol dioxygenase, N-terminal GO:0005506|GO:0009712|GO:0018576|GO:0055114 VAPA_1c01400 cd502a6f96de00a228f811f26b23c11b 288 SUPERFAMILY SSF49482 8 278 1.57E-85 T 12-10-2018 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 VAPA_1c01400 cd502a6f96de00a228f811f26b23c11b 288 ProSitePatterns PS00083 Intradiol ring-cleavage dioxygenases signature. 131 159 - T 12-10-2018 IPR000627 Intradiol ring-cleavage dioxygenase, C-terminal GO:0003824|GO:0006725|GO:0008199|GO:0055114 VAPA_1c01400 cd502a6f96de00a228f811f26b23c11b 288 Gene3D G3DSA:2.60.130.10 4 278 2.9E-97 T 12-10-2018 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 VAPA_1c46870 aba3384e124618491a26db4729a76a27 782 SUPERFAMILY SSF75712 272 324 4.84E-5 T 12-10-2018 VAPA_1c46870 aba3384e124618491a26db4729a76a27 782 Gene3D G3DSA:3.40.50.300 413 622 8.0E-11 T 12-10-2018 VAPA_1c46870 aba3384e124618491a26db4729a76a27 782 Pfam PF13166 AAA domain 12 761 6.5E-178 T 12-10-2018 IPR026866 Protein CR006, P-loop domain VAPA_1c46870 aba3384e124618491a26db4729a76a27 782 SUPERFAMILY SSF52540 10 609 2.96E-14 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c49690 b27c4c7e3ada11182194f5a213e97eac 307 SUPERFAMILY SSF52768 11 302 3.24E-83 T 12-10-2018 IPR023696 Ureohydrolase domain superfamily VAPA_1c49690 b27c4c7e3ada11182194f5a213e97eac 307 Gene3D G3DSA:3.40.800.10 8 305 8.8E-92 T 12-10-2018 VAPA_1c49690 b27c4c7e3ada11182194f5a213e97eac 307 TIGRFAM TIGR01229 rocF_arginase: arginase 11 304 5.9E-85 T 12-10-2018 IPR014033 Arginase GO:0004053|GO:0006525|GO:0046872 KEGG: 00220+3.5.3.1|KEGG: 00330+3.5.3.1|MetaCyc: PWY-31|MetaCyc: PWY-4984|MetaCyc: PWY-6305|MetaCyc: PWY-6922|Reactome: R-HSA-70635 VAPA_1c49690 b27c4c7e3ada11182194f5a213e97eac 307 Pfam PF00491 Arginase family 10 300 8.8E-75 T 12-10-2018 IPR006035 Ureohydrolase GO:0046872 VAPA_1c49690 b27c4c7e3ada11182194f5a213e97eac 307 PRINTS PR00116 Arginase signature 98 113 8.4E-43 T 12-10-2018 IPR006035 Ureohydrolase GO:0046872 VAPA_1c49690 b27c4c7e3ada11182194f5a213e97eac 307 PRINTS PR00116 Arginase signature 125 152 8.4E-43 T 12-10-2018 IPR006035 Ureohydrolase GO:0046872 VAPA_1c49690 b27c4c7e3ada11182194f5a213e97eac 307 PRINTS PR00116 Arginase signature 262 276 8.4E-43 T 12-10-2018 IPR006035 Ureohydrolase GO:0046872 VAPA_1c49690 b27c4c7e3ada11182194f5a213e97eac 307 PRINTS PR00116 Arginase signature 227 256 8.4E-43 T 12-10-2018 IPR006035 Ureohydrolase GO:0046872 VAPA_1c49690 b27c4c7e3ada11182194f5a213e97eac 307 PRINTS PR00116 Arginase signature 179 197 8.4E-43 T 12-10-2018 IPR006035 Ureohydrolase GO:0046872 VAPA_1c49690 b27c4c7e3ada11182194f5a213e97eac 307 PIRSF PIRSF036979 2 304 1.9E-30 T 12-10-2018 IPR006035 Ureohydrolase GO:0046872 VAPA_1c49690 b27c4c7e3ada11182194f5a213e97eac 307 ProSitePatterns PS01053 Arginase family signature. 230 251 - T 12-10-2018 IPR020855 Ureohydrolase, manganese-binding site GO:0016813|GO:0046872 VAPA_1c04150 95d400b3f346c9e08daab7cff465c1e6 236 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 57 1.9E-9 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 VAPA_1c04150 95d400b3f346c9e08daab7cff465c1e6 236 Gene3D G3DSA:1.10.357.10 6 222 1.6E-59 T 12-10-2018 VAPA_1c04150 95d400b3f346c9e08daab7cff465c1e6 236 SUPERFAMILY SSF46689 6 73 4.89E-14 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 VAPA_1c04150 95d400b3f346c9e08daab7cff465c1e6 236 Pfam PF13972 Bacterial transcriptional repressor 63 208 2.0E-42 T 12-10-2018 IPR025722 Bacterial transcriptional repressor TetR VAPA_1c04150 95d400b3f346c9e08daab7cff465c1e6 236 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 13 26 8.6E-8 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 VAPA_1c04150 95d400b3f346c9e08daab7cff465c1e6 236 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 34 57 8.6E-8 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 VAPA_2c08510 15676ff3f1873f337adb814088671e67 330 PIRSF PIRSF017082 2 330 7.2E-83 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_2c08510 15676ff3f1873f337adb814088671e67 330 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 54 326 7.5E-86 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_2c08510 15676ff3f1873f337adb814088671e67 330 Gene3D G3DSA:3.40.190.150 35 320 1.0E-113 T 12-10-2018 VAPA_2c08510 15676ff3f1873f337adb814088671e67 330 Gene3D G3DSA:3.40.190.10 132 255 1.0E-113 T 12-10-2018 VAPA_2c08510 15676ff3f1873f337adb814088671e67 330 SUPERFAMILY SSF53850 119 293 1.81E-13 T 12-10-2018 VAPA_1c09570 4e69705c68f1a070e87a4648581b8487 349 SUPERFAMILY SSF52540 5 205 8.54E-38 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c09570 4e69705c68f1a070e87a4648581b8487 349 SUPERFAMILY SSF90002 254 348 1.09E-25 T 12-10-2018 VAPA_1c09570 4e69705c68f1a070e87a4648581b8487 349 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 5 184 9.1E-52 T 12-10-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain VAPA_1c09570 4e69705c68f1a070e87a4648581b8487 349 Gene3D G3DSA:3.30.1220.10 233 348 3.3E-33 T 12-10-2018 IPR036627 CobW-like, C-terminal domain superfamily VAPA_1c09570 4e69705c68f1a070e87a4648581b8487 349 Gene3D G3DSA:3.40.50.300 3 205 3.5E-69 T 12-10-2018 VAPA_1c09570 4e69705c68f1a070e87a4648581b8487 349 Pfam PF07683 Cobalamin synthesis protein cobW C-terminal domain 254 348 2.7E-23 T 12-10-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal VAPA_1c09570 4e69705c68f1a070e87a4648581b8487 349 SMART SM00833 254 348 9.9E-18 T 12-10-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal VAPA_1c01900 d71149960528a162bea75913a3d3128c 254 Pfam PF07702 UTRA domain 104 239 3.2E-35 T 12-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 VAPA_1c01900 d71149960528a162bea75913a3d3128c 254 SMART SM00345 23 82 1.5E-19 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_1c01900 d71149960528a162bea75913a3d3128c 254 Gene3D G3DSA:1.10.10.10 16 83 1.4E-24 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c01900 d71149960528a162bea75913a3d3128c 254 SMART SM00866 103 240 4.9E-36 T 12-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 VAPA_1c01900 d71149960528a162bea75913a3d3128c 254 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 56 72 2.7E-9 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_1c01900 d71149960528a162bea75913a3d3128c 254 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 42 56 2.7E-9 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_1c01900 d71149960528a162bea75913a3d3128c 254 SUPERFAMILY SSF64288 70 246 4.4E-44 T 12-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily VAPA_1c01900 d71149960528a162bea75913a3d3128c 254 Pfam PF00392 Bacterial regulatory proteins, gntR family 19 82 1.5E-19 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_1c01900 d71149960528a162bea75913a3d3128c 254 SUPERFAMILY SSF46785 15 86 5.74E-23 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c01900 d71149960528a162bea75913a3d3128c 254 TIGRFAM TIGR02018 his_ut_repres: histidine utilization repressor 19 246 4.1E-92 T 12-10-2018 IPR010248 Histidine utilization repressor GO:0003677|GO:0006547|GO:0045892 VAPA_1c01900 d71149960528a162bea75913a3d3128c 254 Gene3D G3DSA:3.40.1410.10 101 236 3.4E-35 T 12-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily VAPA_1c43750 95088d0e434f3b7cf61c2cf3018cfeb8 103 Pfam PF00829 Ribosomal prokaryotic L21 protein 1 101 2.5E-39 T 12-10-2018 IPR028909 Ribosomal protein L21-like GO:0005840 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 VAPA_1c43750 95088d0e434f3b7cf61c2cf3018cfeb8 103 TIGRFAM TIGR00061 L21: ribosomal protein bL21 2 101 5.2E-36 T 12-10-2018 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 VAPA_1c43750 95088d0e434f3b7cf61c2cf3018cfeb8 103 ProSitePatterns PS01169 Ribosomal protein L21 signature. 72 94 - T 12-10-2018 IPR018258 Ribosomal protein L21, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 VAPA_1c43750 95088d0e434f3b7cf61c2cf3018cfeb8 103 SUPERFAMILY SSF141091 1 101 8.89E-37 T 12-10-2018 IPR036164 L21-like superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 VAPA_1c43750 95088d0e434f3b7cf61c2cf3018cfeb8 103 Hamap MF_01363 50S ribosomal protein L21 [rplU]. 1 103 26.982 T 12-10-2018 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 VAPA_1c09680 29dff277f46627a17aed728da8deb3d5 475 Gene3D G3DSA:3.90.190.20 325 467 3.7E-39 T 12-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 VAPA_1c09680 29dff277f46627a17aed728da8deb3d5 475 TIGRFAM TIGR01143 murF: UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase 35 461 5.2E-118 T 12-10-2018 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 VAPA_1c09680 29dff277f46627a17aed728da8deb3d5 475 SUPERFAMILY SSF53623 106 321 7.33E-51 T 12-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 VAPA_1c09680 29dff277f46627a17aed728da8deb3d5 475 Pfam PF01225 Mur ligase family, catalytic domain 30 102 1.4E-8 T 12-10-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 VAPA_1c09680 29dff277f46627a17aed728da8deb3d5 475 SUPERFAMILY SSF63418 8 104 3.66E-19 T 12-10-2018 IPR035911 MurE/MurF, N-terminal VAPA_1c09680 29dff277f46627a17aed728da8deb3d5 475 Pfam PF02875 Mur ligase family, glutamate ligase domain 339 406 4.1E-12 T 12-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 VAPA_1c09680 29dff277f46627a17aed728da8deb3d5 475 Pfam PF08245 Mur ligase middle domain 112 304 4.2E-41 T 12-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 VAPA_1c09680 29dff277f46627a17aed728da8deb3d5 475 SUPERFAMILY SSF53244 337 462 2.98E-33 T 12-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 VAPA_1c09680 29dff277f46627a17aed728da8deb3d5 475 Hamap MF_02019 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [murF]. 8 463 31.668 T 12-10-2018 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 VAPA_1c09680 29dff277f46627a17aed728da8deb3d5 475 Gene3D G3DSA:3.40.1390.10 6 87 2.0E-19 T 12-10-2018 VAPA_1c09680 29dff277f46627a17aed728da8deb3d5 475 Gene3D G3DSA:3.40.1190.10 88 321 3.6E-68 T 12-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 VAPA_1c30170 234bce47be10a2636537452a05d19ec8 222 Pfam PF00392 Bacterial regulatory proteins, gntR family 9 70 9.6E-17 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_1c30170 234bce47be10a2636537452a05d19ec8 222 SMART SM00345 12 70 7.6E-14 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_1c30170 234bce47be10a2636537452a05d19ec8 222 SUPERFAMILY SSF48008 77 212 2.38E-23 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal VAPA_1c30170 234bce47be10a2636537452a05d19ec8 222 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 44 60 6.4E-6 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_1c30170 234bce47be10a2636537452a05d19ec8 222 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 30 44 6.4E-6 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_1c30170 234bce47be10a2636537452a05d19ec8 222 Gene3D G3DSA:1.10.10.10 5 71 1.7E-23 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c30170 234bce47be10a2636537452a05d19ec8 222 Pfam PF07729 FCD domain 80 203 1.7E-24 T 12-10-2018 IPR011711 GntR, C-terminal VAPA_1c30170 234bce47be10a2636537452a05d19ec8 222 SMART SM00895 80 204 1.2E-17 T 12-10-2018 IPR011711 GntR, C-terminal VAPA_1c30170 234bce47be10a2636537452a05d19ec8 222 SUPERFAMILY SSF46785 7 74 6.59E-20 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c30170 234bce47be10a2636537452a05d19ec8 222 Gene3D G3DSA:1.20.120.530 74 220 1.8E-27 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal VAPA_2c11510 e2e7b81688795de6a55ae2a68e845afb 185 Gene3D G3DSA:3.40.50.300 4 150 2.7E-12 T 12-10-2018 VAPA_2c11510 e2e7b81688795de6a55ae2a68e845afb 185 Gene3D G3DSA:3.30.63.10 37 94 2.7E-12 T 12-10-2018 VAPA_2c11510 e2e7b81688795de6a55ae2a68e845afb 185 Hamap MF_00836 Ribose 1,5-bisphosphate phosphokinase PhnN [phnN]. 2 180 34.372 T 12-10-2018 IPR012699 Ribose 1,5-bisphosphate phosphokinase PhnN GO:0006015|GO:0033863 KEGG: 00030+2.7.4.23|MetaCyc: PWY-7805|MetaCyc: PWY-7807 VAPA_2c11510 e2e7b81688795de6a55ae2a68e845afb 185 TIGRFAM TIGR02322 phosphon_PhnN: phosphonate metabolism protein/1,5-bisphosphokinase (PRPP-forming) PhnN 3 180 2.3E-52 T 12-10-2018 IPR012699 Ribose 1,5-bisphosphate phosphokinase PhnN GO:0006015|GO:0033863 KEGG: 00030+2.7.4.23|MetaCyc: PWY-7805|MetaCyc: PWY-7807 VAPA_2c11510 e2e7b81688795de6a55ae2a68e845afb 185 SUPERFAMILY SSF52540 3 183 2.4E-29 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c31120 ce07181d8bb4ad3b323d960f22dbbbd2 181 SUPERFAMILY SSF55961 34 178 9.99E-31 T 12-10-2018 VAPA_1c31120 ce07181d8bb4ad3b323d960f22dbbbd2 181 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 34 179 3.7E-33 T 12-10-2018 IPR019587 Polyketide cyclase/dehydrase VAPA_1c31120 ce07181d8bb4ad3b323d960f22dbbbd2 181 Gene3D G3DSA:3.30.530.20 32 180 9.1E-42 T 12-10-2018 IPR023393 START-like domain superfamily VAPA_1c50110 5240b9327982ced545de0b729fbfaa89 251 Pfam PF00561 alpha/beta hydrolase fold 2 110 4.2E-23 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 VAPA_1c50110 5240b9327982ced545de0b729fbfaa89 251 PRINTS PR00111 Alpha/beta hydrolase fold signature 25 40 1.6E-11 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 VAPA_1c50110 5240b9327982ced545de0b729fbfaa89 251 PRINTS PR00111 Alpha/beta hydrolase fold signature 84 97 1.6E-11 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 VAPA_1c50110 5240b9327982ced545de0b729fbfaa89 251 PRINTS PR00111 Alpha/beta hydrolase fold signature 70 83 1.6E-11 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 VAPA_1c50110 5240b9327982ced545de0b729fbfaa89 251 PRINTS PR00111 Alpha/beta hydrolase fold signature 187 201 1.6E-11 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 VAPA_1c50110 5240b9327982ced545de0b729fbfaa89 251 SUPERFAMILY SSF53474 1 242 2.32E-51 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c50110 5240b9327982ced545de0b729fbfaa89 251 TIGRFAM TIGR03611 RutD: pyrimidine utilization protein D 1 242 8.8E-101 T 12-10-2018 IPR019913 Pyrimidine utilisation protein RutD GO:0006212|GO:0016811 VAPA_1c50110 5240b9327982ced545de0b729fbfaa89 251 Hamap MF_00832 Putative aminoacrylate hydrolase RutD [rutD]. 1 244 46.862 T 12-10-2018 IPR019913 Pyrimidine utilisation protein RutD GO:0006212|GO:0016811 VAPA_1c50110 5240b9327982ced545de0b729fbfaa89 251 Gene3D G3DSA:3.40.50.1820 1 245 6.9E-63 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c47830 91e1b8b66dab4dbded699bde5ecbc882 367 Gene3D G3DSA:1.10.260.40 3 59 8.2E-25 T 12-10-2018 VAPA_1c47830 91e1b8b66dab4dbded699bde5ecbc882 367 ProSitePatterns PS00356 LacI-type HTH domain signature. 4 22 - T 12-10-2018 VAPA_1c47830 91e1b8b66dab4dbded699bde5ecbc882 367 Pfam PF13377 Periplasmic binding protein-like domain 170 332 5.7E-44 T 12-10-2018 VAPA_1c47830 91e1b8b66dab4dbded699bde5ecbc882 367 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 13 23 3.2E-5 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 VAPA_1c47830 91e1b8b66dab4dbded699bde5ecbc882 367 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 3 13 3.2E-5 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 VAPA_1c47830 91e1b8b66dab4dbded699bde5ecbc882 367 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 48 2.4E-20 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 VAPA_1c47830 91e1b8b66dab4dbded699bde5ecbc882 367 Gene3D G3DSA:3.40.50.2300 62 324 5.2E-88 T 12-10-2018 VAPA_1c47830 91e1b8b66dab4dbded699bde5ecbc882 367 SUPERFAMILY SSF53822 61 334 8.83E-86 T 12-10-2018 IPR028082 Periplasmic binding protein-like I VAPA_1c47830 91e1b8b66dab4dbded699bde5ecbc882 367 SUPERFAMILY SSF47413 1 59 1.65E-18 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 VAPA_1c47830 91e1b8b66dab4dbded699bde5ecbc882 367 SMART SM00354 1 71 1.1E-36 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 VAPA_1c47830 91e1b8b66dab4dbded699bde5ecbc882 367 Gene3D G3DSA:3.40.50.2300 162 329 5.2E-88 T 12-10-2018 VAPA_1c45590 3321a2455574a50d636b1ddd498c5e54 73 Pfam PF11137 Protein of unknown function (DUF2909) 1 64 3.4E-20 T 12-10-2018 IPR021313 Protein of unknown function DUF2909 VAPA_1c30640 e51f5f8593a69bcddc03ae79bddc229e 485 SMART SM00060 338 411 0.0016 T 12-10-2018 IPR003961 Fibronectin type III GO:0005515 VAPA_1c30640 e51f5f8593a69bcddc03ae79bddc229e 485 SUPERFAMILY SSF53474 34 331 7.45E-84 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c30640 e51f5f8593a69bcddc03ae79bddc229e 485 Gene3D G3DSA:3.40.50.1820 220 337 1.2E-11 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c30640 e51f5f8593a69bcddc03ae79bddc229e 485 Gene3D G3DSA:2.60.40.10 344 419 1.7E-13 T 12-10-2018 IPR013783 Immunoglobulin-like fold VAPA_1c30640 e51f5f8593a69bcddc03ae79bddc229e 485 Gene3D G3DSA:3.40.50.1820 1 181 9.6E-8 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c30640 e51f5f8593a69bcddc03ae79bddc229e 485 Pfam PF10503 Esterase PHB depolymerase 239 326 2.2E-6 T 12-10-2018 IPR010126 Esterase, PHB depolymerase GO:0005576|GO:0016787 VAPA_1c30640 e51f5f8593a69bcddc03ae79bddc229e 485 SUPERFAMILY SSF49265 339 423 2.49E-10 T 12-10-2018 IPR036116 Fibronectin type III superfamily GO:0005515 VAPA_2c00860 2622105f44df39d3125dd04aa376622a 301 Pfam PF03466 LysR substrate binding domain 92 296 2.9E-37 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_2c00860 2622105f44df39d3125dd04aa376622a 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 44 9.0E-7 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_2c00860 2622105f44df39d3125dd04aa376622a 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 44 55 9.0E-7 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_2c00860 2622105f44df39d3125dd04aa376622a 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 23 34 9.0E-7 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_2c00860 2622105f44df39d3125dd04aa376622a 301 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 10 67 6.5E-20 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_2c00860 2622105f44df39d3125dd04aa376622a 301 SUPERFAMILY SSF53850 93 299 8.22E-40 T 12-10-2018 VAPA_2c00860 2622105f44df39d3125dd04aa376622a 301 Gene3D G3DSA:3.40.190.290 95 295 2.3E-48 T 12-10-2018 VAPA_2c00860 2622105f44df39d3125dd04aa376622a 301 SUPERFAMILY SSF46785 7 88 3.76E-22 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_2c00860 2622105f44df39d3125dd04aa376622a 301 Gene3D G3DSA:1.10.10.10 7 92 4.9E-26 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_2c12680 8af86427b3d25584009b185c377881bd 133 TIGRFAM TIGR00223 panD: aspartate 1-decarboxylase 1 125 2.5E-51 T 12-10-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 VAPA_2c12680 8af86427b3d25584009b185c377881bd 133 Pfam PF02261 Aspartate decarboxylase 1 114 3.6E-48 T 12-10-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 VAPA_2c12680 8af86427b3d25584009b185c377881bd 133 PIRSF PIRSF006246 1 131 7.7E-49 T 12-10-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 VAPA_2c12680 8af86427b3d25584009b185c377881bd 133 ProDom PD009294 ASPARTATE 1-DECARBOXYLASE DECARBOXYLASE CHAIN LYASE ALPHA ALPHA- CONTAINS: PRECURSOR BETA 5 123 1.0E-51 T 12-10-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 VAPA_2c12680 8af86427b3d25584009b185c377881bd 133 Hamap MF_00446 Aspartate 1-decarboxylase [panD]. 1 127 71.261 T 12-10-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 VAPA_2c12680 8af86427b3d25584009b185c377881bd 133 SUPERFAMILY SSF50692 1 120 4.47E-48 T 12-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily VAPA_2c12680 8af86427b3d25584009b185c377881bd 133 Gene3D G3DSA:2.40.40.20 1 126 3.0E-54 T 12-10-2018 VAPA_1c51640 1a6611896fc114808cb44b9833569acc 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 3.5E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c51640 1a6611896fc114808cb44b9833569acc 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 3.5E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c51640 1a6611896fc114808cb44b9833569acc 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 3.5E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c51640 1a6611896fc114808cb44b9833569acc 301 Pfam PF03466 LysR substrate binding domain 91 287 1.3E-39 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_1c51640 1a6611896fc114808cb44b9833569acc 301 SUPERFAMILY SSF53850 92 289 1.36E-38 T 12-10-2018 VAPA_1c51640 1a6611896fc114808cb44b9833569acc 301 Gene3D G3DSA:3.40.190.10 91 284 3.1E-46 T 12-10-2018 VAPA_1c51640 1a6611896fc114808cb44b9833569acc 301 SUPERFAMILY SSF46785 2 110 1.92E-22 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c51640 1a6611896fc114808cb44b9833569acc 301 Gene3D G3DSA:3.40.190.10 162 267 3.1E-46 T 12-10-2018 VAPA_1c51640 1a6611896fc114808cb44b9833569acc 301 Gene3D G3DSA:1.10.10.10 1 85 4.5E-26 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c51640 1a6611896fc114808cb44b9833569acc 301 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 2.4E-19 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c11620 554dc63185ef0be2c4db09e9c2b742e2 324 SUPERFAMILY SSF53850 112 276 1.9E-14 T 12-10-2018 VAPA_1c11620 554dc63185ef0be2c4db09e9c2b742e2 324 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 48 320 3.5E-77 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c11620 554dc63185ef0be2c4db09e9c2b742e2 324 PIRSF PIRSF017082 1 324 3.2E-78 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c11620 554dc63185ef0be2c4db09e9c2b742e2 324 Gene3D G3DSA:3.40.190.150 29 314 1.8E-105 T 12-10-2018 VAPA_1c11620 554dc63185ef0be2c4db09e9c2b742e2 324 Gene3D G3DSA:3.40.190.10 126 249 1.8E-105 T 12-10-2018 VAPA_1c30140 91fc9f42df69c191e111e9ead32f1011 511 Gene3D G3DSA:3.30.300.310 408 509 3.1E-29 T 12-10-2018 VAPA_1c30140 91fc9f42df69c191e111e9ead32f1011 511 Gene3D G3DSA:3.40.50.12780 14 405 4.8E-123 T 12-10-2018 VAPA_1c30140 91fc9f42df69c191e111e9ead32f1011 511 ProSitePatterns PS00455 Putative AMP-binding domain signature. 166 177 - T 12-10-2018 IPR020845 AMP-binding, conserved site VAPA_1c30140 91fc9f42df69c191e111e9ead32f1011 511 Pfam PF00501 AMP-binding enzyme 24 412 3.5E-92 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 VAPA_1c30140 91fc9f42df69c191e111e9ead32f1011 511 SUPERFAMILY SSF56801 10 508 7.85E-142 T 12-10-2018 VAPA_1c30140 91fc9f42df69c191e111e9ead32f1011 511 Pfam PF13193 AMP-binding enzyme C-terminal domain 421 496 6.9E-16 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain VAPA_1c47990 ea78976745f290b1ca3b3f47ea003eaf 289 SUPERFAMILY SSF56300 34 271 9.65E-34 T 12-10-2018 VAPA_1c47990 ea78976745f290b1ca3b3f47ea003eaf 289 Pfam PF00149 Calcineurin-like phosphoesterase 34 233 4.4E-13 T 12-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 VAPA_1c47990 ea78976745f290b1ca3b3f47ea003eaf 289 Gene3D G3DSA:3.60.21.10 33 267 6.9E-18 T 12-10-2018 IPR029052 Metallo-dependent phosphatase-like VAPA_1c43280 3ca3c559e454be2193d410ba3122c7d0 478 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 386 395 - T 12-10-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 VAPA_1c43280 3ca3c559e454be2193d410ba3122c7d0 478 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 180 395 6.9E-73 T 12-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 VAPA_1c43280 3ca3c559e454be2193d410ba3122c7d0 478 SMART SM00382 192 379 5.4E-7 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c43280 3ca3c559e454be2193d410ba3122c7d0 478 Gene3D G3DSA:3.40.50.12240 32 478 1.1E-160 T 12-10-2018 VAPA_1c43280 3ca3c559e454be2193d410ba3122c7d0 478 TIGRFAM TIGR01026 fliI_yscN: ATPase, FliI/YscN family 29 475 1.3E-176 T 12-10-2018 IPR005714 ATPase, type III secretion system, FliI/YscN GO:0005737|GO:0009058|GO:0016887|GO:0030254|GO:0030257 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 VAPA_1c43280 3ca3c559e454be2193d410ba3122c7d0 478 TIGRFAM TIGR03496 FliI_clade1: flagellar protein export ATPase FliI 41 472 3.9E-196 T 12-10-2018 IPR020005 Flagellar export ATPase FliI, clade 1 GO:0016887|GO:0044780|GO:0071973 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 VAPA_1c43280 3ca3c559e454be2193d410ba3122c7d0 478 SUPERFAMILY SSF52540 127 401 2.35E-94 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c04740 f195e987b61d010ff21cfb462029c17f 344 SUPERFAMILY SSF52540 3 252 2.18E-66 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c04740 f195e987b61d010ff21cfb462029c17f 344 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 231 319 4.5E-21 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 VAPA_1c04740 f195e987b61d010ff21cfb462029c17f 344 SMART SM00382 32 239 2.0E-12 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c04740 f195e987b61d010ff21cfb462029c17f 344 Gene3D G3DSA:3.40.50.300 1 326 2.1E-94 T 12-10-2018 VAPA_1c04740 f195e987b61d010ff21cfb462029c17f 344 Pfam PF00005 ABC transporter 24 181 2.7E-27 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c04740 f195e987b61d010ff21cfb462029c17f 344 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 233 298 5.0E-18 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 VAPA_1c31560 24534f3c6bdf56ca49392d59e89db9d6 326 Gene3D G3DSA:3.90.226.10 1 319 1.3E-120 T 12-10-2018 VAPA_1c31560 24534f3c6bdf56ca49392d59e89db9d6 326 SUPERFAMILY SSF52096 6 317 3.45E-101 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily VAPA_1c31560 24534f3c6bdf56ca49392d59e89db9d6 326 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 89 100 2.7E-45 T 12-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 VAPA_1c31560 24534f3c6bdf56ca49392d59e89db9d6 326 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 135 151 2.7E-45 T 12-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 VAPA_1c31560 24534f3c6bdf56ca49392d59e89db9d6 326 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 170 183 2.7E-45 T 12-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 VAPA_1c31560 24534f3c6bdf56ca49392d59e89db9d6 326 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 198 207 2.7E-45 T 12-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 VAPA_1c31560 24534f3c6bdf56ca49392d59e89db9d6 326 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 114 132 2.7E-45 T 12-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 VAPA_1c31560 24534f3c6bdf56ca49392d59e89db9d6 326 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 154 167 2.7E-45 T 12-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 VAPA_1c31560 24534f3c6bdf56ca49392d59e89db9d6 326 Pfam PF03255 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit 6 149 1.0E-66 T 12-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 VAPA_1c31560 24534f3c6bdf56ca49392d59e89db9d6 326 TIGRFAM TIGR00513 accA: acetyl-CoA carboxylase, carboxyl transferase, alpha subunit 4 320 1.2E-153 T 12-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 VAPA_1c31560 24534f3c6bdf56ca49392d59e89db9d6 326 Hamap MF_00823 Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha [accA]. 6 317 50.363 T 12-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 VAPA_1c03920 3ef63bed9749e9591fd7a805bc8d3c09 670 SUPERFAMILY SSF51230 593 667 1.57E-17 T 12-10-2018 IPR011053 Single hybrid motif VAPA_1c03920 3ef63bed9749e9591fd7a805bc8d3c09 670 Gene3D G3DSA:2.40.50.100 601 667 1.7E-19 T 12-10-2018 VAPA_1c03920 3ef63bed9749e9591fd7a805bc8d3c09 670 Gene3D G3DSA:3.30.470.130 12 469 3.8E-191 T 12-10-2018 VAPA_1c03920 3ef63bed9749e9591fd7a805bc8d3c09 670 Pfam PF00364 Biotin-requiring enzyme 605 667 4.5E-13 T 12-10-2018 IPR000089 Biotin/lipoyl attachment VAPA_1c03920 3ef63bed9749e9591fd7a805bc8d3c09 670 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 308 315 - T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 VAPA_1c03920 3ef63bed9749e9591fd7a805bc8d3c09 670 SUPERFAMILY SSF56059 105 370 1.5E-67 T 12-10-2018 VAPA_1c03920 3ef63bed9749e9591fd7a805bc8d3c09 670 SUPERFAMILY SSF52440 17 135 6.26E-49 T 12-10-2018 IPR016185 Pre-ATP-grasp domain superfamily VAPA_1c03920 3ef63bed9749e9591fd7a805bc8d3c09 670 SMART SM00878 358 462 4.6E-44 T 12-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 VAPA_1c03920 3ef63bed9749e9591fd7a805bc8d3c09 670 Pfam PF02785 Biotin carboxylase C-terminal domain 358 462 8.6E-29 T 12-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 VAPA_1c03920 3ef63bed9749e9591fd7a805bc8d3c09 670 SUPERFAMILY SSF51246 353 468 1.94E-32 T 12-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 VAPA_1c03920 3ef63bed9749e9591fd7a805bc8d3c09 670 Pfam PF00289 Biotin carboxylase, N-terminal domain 24 132 2.2E-44 T 12-10-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 VAPA_1c03920 3ef63bed9749e9591fd7a805bc8d3c09 670 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 137 344 1.3E-74 T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 VAPA_1c39010 c7549d608b735b2617cd0b0bdb19f5cf 117 SUPERFAMILY SSF55298 4 115 3.77E-29 T 12-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 VAPA_1c39010 c7549d608b735b2617cd0b0bdb19f5cf 117 Pfam PF01042 Endoribonuclease L-PSP 14 115 1.2E-24 T 12-10-2018 IPR006175 YjgF/YER057c/UK114 family Reactome: R-HSA-8849175 VAPA_1c39010 c7549d608b735b2617cd0b0bdb19f5cf 117 ProSitePatterns PS01094 Uncharacterized protein family UPF0076 signature. 92 110 - T 12-10-2018 IPR019897 RidA, conserved site Reactome: R-HSA-8849175 VAPA_1c39010 c7549d608b735b2617cd0b0bdb19f5cf 117 Gene3D G3DSA:3.30.1330.40 1 117 1.8E-39 T 12-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 VAPA_1c40870 0295197167ef1505d502477c51c146cb 444 PRINTS PR00173 Glutamate-aspartate symporter signature 294 320 2.9E-28 T 12-10-2018 VAPA_1c40870 0295197167ef1505d502477c51c146cb 444 PRINTS PR00173 Glutamate-aspartate symporter signature 73 98 2.9E-28 T 12-10-2018 VAPA_1c40870 0295197167ef1505d502477c51c146cb 444 PRINTS PR00173 Glutamate-aspartate symporter signature 6 26 2.9E-28 T 12-10-2018 VAPA_1c40870 0295197167ef1505d502477c51c146cb 444 PRINTS PR00173 Glutamate-aspartate symporter signature 147 169 2.9E-28 T 12-10-2018 VAPA_1c40870 0295197167ef1505d502477c51c146cb 444 PRINTS PR00173 Glutamate-aspartate symporter signature 194 213 2.9E-28 T 12-10-2018 VAPA_1c40870 0295197167ef1505d502477c51c146cb 444 PRINTS PR00173 Glutamate-aspartate symporter signature 329 348 2.9E-28 T 12-10-2018 VAPA_1c40870 0295197167ef1505d502477c51c146cb 444 SUPERFAMILY SSF118215 8 404 3.92E-108 T 12-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 VAPA_1c40870 0295197167ef1505d502477c51c146cb 444 ProSitePatterns PS00714 Sodium:dicarboxylate symporter family signature 2. 297 320 - T 12-10-2018 IPR018107 Sodium:dicarboxylate symporter, conserved site VAPA_1c40870 0295197167ef1505d502477c51c146cb 444 Gene3D G3DSA:1.10.3860.10 3 420 7.0E-111 T 12-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 VAPA_1c40870 0295197167ef1505d502477c51c146cb 444 Pfam PF00375 Sodium:dicarboxylate symporter family 8 403 1.5E-96 T 12-10-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 VAPA_2c12390 2710860d1d7e1b9b41b386468fcb1deb 278 PRINTS PR00111 Alpha/beta hydrolase fold signature 114 127 5.9E-9 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 VAPA_2c12390 2710860d1d7e1b9b41b386468fcb1deb 278 PRINTS PR00111 Alpha/beta hydrolase fold signature 57 72 5.9E-9 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 VAPA_2c12390 2710860d1d7e1b9b41b386468fcb1deb 278 PRINTS PR00111 Alpha/beta hydrolase fold signature 222 236 5.9E-9 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 VAPA_2c12390 2710860d1d7e1b9b41b386468fcb1deb 278 PRINTS PR00111 Alpha/beta hydrolase fold signature 100 113 5.9E-9 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 VAPA_2c12390 2710860d1d7e1b9b41b386468fcb1deb 278 Pfam PF00561 alpha/beta hydrolase fold 39 263 2.9E-22 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 VAPA_2c12390 2710860d1d7e1b9b41b386468fcb1deb 278 Gene3D G3DSA:3.40.50.1820 3 277 3.8E-64 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_2c12390 2710860d1d7e1b9b41b386468fcb1deb 278 SUPERFAMILY SSF53474 9 278 1.98E-53 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c45620 81122ace529b85c579462e66cc0f1a84 208 SUPERFAMILY SSF110111 69 189 5.1E-46 T 12-10-2018 IPR023471 Cytochrome c oxidase assembly protein CtaG/Cox11, domain superfamily Reactome: R-HSA-5628897|Reactome: R-HSA-611105 VAPA_1c45620 81122ace529b85c579462e66cc0f1a84 208 PIRSF PIRSF005413 1 205 2.9E-60 T 12-10-2018 IPR007533 Cytochrome c oxidase assembly protein CtaG/Cox11 GO:0005507 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 VAPA_1c45620 81122ace529b85c579462e66cc0f1a84 208 Gene3D G3DSA:2.60.370.10 68 204 2.0E-44 T 12-10-2018 IPR023471 Cytochrome c oxidase assembly protein CtaG/Cox11, domain superfamily Reactome: R-HSA-5628897|Reactome: R-HSA-611105 VAPA_1c45620 81122ace529b85c579462e66cc0f1a84 208 Pfam PF04442 Cytochrome c oxidase assembly protein CtaG/Cox11 32 186 5.6E-49 T 12-10-2018 IPR007533 Cytochrome c oxidase assembly protein CtaG/Cox11 GO:0005507 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 VAPA_2c13230 0a5ab75d0322f21a11075b204feb1732 382 Gene3D G3DSA:3.30.450.90 39 145 3.1E-37 T 12-10-2018 VAPA_2c13230 0a5ab75d0322f21a11075b204feb1732 382 Gene3D G3DSA:3.40.50.300 149 381 3.6E-56 T 12-10-2018 VAPA_2c13230 0a5ab75d0322f21a11075b204feb1732 382 TIGRFAM TIGR02788 VirB11: P-type DNA transfer ATPase VirB11 51 372 3.0E-99 T 12-10-2018 IPR014155 Type IV secretion system protein VirB11 GO:0043684|GO:0044097 VAPA_2c13230 0a5ab75d0322f21a11075b204feb1732 382 SUPERFAMILY SSF52540 43 357 7.5E-39 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_2c13230 0a5ab75d0322f21a11075b204feb1732 382 Pfam PF00437 Type II/IV secretion system protein 46 356 3.9E-57 T 12-10-2018 IPR001482 Type II/IV secretion system protein VAPA_1c52730 a5eedfd5f3a4ff531e1d12d979cbee8f 274 ProSitePatterns PS00156 Orotidine 5'-phosphate decarboxylase active site. 90 103 - T 12-10-2018 IPR018089 Orotidine 5'-phosphate decarboxylase, active site GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 VAPA_1c52730 a5eedfd5f3a4ff531e1d12d979cbee8f 274 Hamap MF_01215 Orotidine 5'-phosphate decarboxylase [pyrF]. 2 271 36.488 T 12-10-2018 IPR011995 Orotidine 5'-phosphate decarboxylase, type 2 GO:0004590|GO:0006221 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 VAPA_1c52730 a5eedfd5f3a4ff531e1d12d979cbee8f 274 SMART SM00934 17 258 1.2E-45 T 12-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 VAPA_1c52730 a5eedfd5f3a4ff531e1d12d979cbee8f 274 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 17 249 6.0E-28 T 12-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 VAPA_1c52730 a5eedfd5f3a4ff531e1d12d979cbee8f 274 TIGRFAM TIGR02127 pyrF_sub2: orotidine 5'-phosphate decarboxylase 3 258 6.5E-73 T 12-10-2018 IPR011995 Orotidine 5'-phosphate decarboxylase, type 2 GO:0004590|GO:0006221 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 VAPA_1c52730 a5eedfd5f3a4ff531e1d12d979cbee8f 274 SUPERFAMILY SSF51366 3 266 1.45E-69 T 12-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 VAPA_1c52730 a5eedfd5f3a4ff531e1d12d979cbee8f 274 Gene3D G3DSA:3.20.20.70 1 270 2.5E-96 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 VAPA_1c26550 db308227bd37ece36f16ca483f1740ad 204 TIGRFAM TIGR04025 PPOX_FMN_DR2398: pyridoxamine 5'-phosphate oxidase, FMN-binding family 10 204 1.0E-78 T 12-10-2018 IPR024029 Pyridoxamine 5-phosphate oxidase, FMN-dependent VAPA_1c26550 db308227bd37ece36f16ca483f1740ad 204 Gene3D G3DSA:2.30.110.10 30 159 3.2E-22 T 12-10-2018 IPR012349 FMN-binding split barrel GO:0048037 VAPA_1c26550 db308227bd37ece36f16ca483f1740ad 204 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 30 123 3.0E-14 T 12-10-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 VAPA_1c26550 db308227bd37ece36f16ca483f1740ad 204 SUPERFAMILY SSF50475 26 153 2.55E-22 T 12-10-2018 VAPA_2c02340 d27a8c3d169a94a7fccf349c2b1b64e9 296 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 65 6.1E-16 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_2c02340 d27a8c3d169a94a7fccf349c2b1b64e9 296 SUPERFAMILY SSF53850 91 285 1.27E-35 T 12-10-2018 VAPA_2c02340 d27a8c3d169a94a7fccf349c2b1b64e9 296 SUPERFAMILY SSF46785 4 114 6.46E-23 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_2c02340 d27a8c3d169a94a7fccf349c2b1b64e9 296 Gene3D G3DSA:1.10.10.10 4 93 6.2E-21 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_2c02340 d27a8c3d169a94a7fccf349c2b1b64e9 296 Gene3D G3DSA:3.40.190.290 94 289 4.4E-35 T 12-10-2018 VAPA_2c02340 d27a8c3d169a94a7fccf349c2b1b64e9 296 Pfam PF03466 LysR substrate binding domain 91 280 9.1E-37 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_1c08950 8e309001c3b1f04a52f015b72af86227 432 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 7 422 1.4E-92 T 12-10-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit VAPA_1c08950 8e309001c3b1f04a52f015b72af86227 432 PIRSF PIRSF006066 1 432 3.1E-118 T 12-10-2018 IPR004681 TRAP transporter large membrane protein DctM GO:0016021 VAPA_1c08950 8e309001c3b1f04a52f015b72af86227 432 TIGRFAM TIGR00786 dctM: TRAP transporter, DctM subunit 17 427 7.7E-101 T 12-10-2018 IPR004681 TRAP transporter large membrane protein DctM GO:0016021 VAPA_1c33960 c7eda5c4b127e8a8ccde6a7cb818db82 140 Gene3D G3DSA:3.10.129.10 10 139 1.6E-32 T 12-10-2018 VAPA_1c33960 c7eda5c4b127e8a8ccde6a7cb818db82 140 SUPERFAMILY SSF54637 10 138 2.42E-31 T 12-10-2018 IPR029069 HotDog domain superfamily VAPA_1c33960 c7eda5c4b127e8a8ccde6a7cb818db82 140 Pfam PF13279 Thioesterase-like superfamily 20 135 2.7E-11 T 12-10-2018 VAPA_1c41980 3277ae3bd4987a94ab16e82397b5af96 473 Gene3D G3DSA:1.10.287.130 202 285 7.5E-6 T 12-10-2018 VAPA_1c41980 3277ae3bd4987a94ab16e82397b5af96 473 SUPERFAMILY SSF47384 214 285 7.85E-6 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 VAPA_1c41980 3277ae3bd4987a94ab16e82397b5af96 473 Gene3D G3DSA:3.30.565.10 286 437 5.1E-22 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_1c41980 3277ae3bd4987a94ab16e82397b5af96 473 SMART SM00387 333 438 3.2E-16 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase VAPA_1c41980 3277ae3bd4987a94ab16e82397b5af96 473 PRINTS PR00344 Bacterial sensor protein C-terminal signature 422 435 3.1E-6 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c41980 3277ae3bd4987a94ab16e82397b5af96 473 PRINTS PR00344 Bacterial sensor protein C-terminal signature 368 382 3.1E-6 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c41980 3277ae3bd4987a94ab16e82397b5af96 473 PRINTS PR00344 Bacterial sensor protein C-terminal signature 398 416 3.1E-6 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c41980 3277ae3bd4987a94ab16e82397b5af96 473 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 336 437 6.0E-13 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase VAPA_1c41980 3277ae3bd4987a94ab16e82397b5af96 473 SUPERFAMILY SSF55874 297 438 1.02E-21 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_1c52880 05addff51bb828c5bde185a67f1d1ddf 354 PIRSF PIRSF001359 1 329 2.8E-86 T 12-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 VAPA_1c52880 05addff51bb828c5bde185a67f1d1ddf 354 SUPERFAMILY SSF51569 1 328 3.96E-107 T 12-10-2018 VAPA_1c52880 05addff51bb828c5bde185a67f1d1ddf 354 TIGRFAM TIGR00167 cbbA: ketose-bisphosphate aldolase 1 328 2.2E-101 T 12-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 VAPA_1c52880 05addff51bb828c5bde185a67f1d1ddf 354 ProSitePatterns PS00806 Fructose-bisphosphate aldolase class-II signature 2. 139 150 - T 12-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 VAPA_1c52880 05addff51bb828c5bde185a67f1d1ddf 354 ProSitePatterns PS00602 Fructose-bisphosphate aldolase class-II signature 1. 73 85 - T 12-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 VAPA_1c52880 05addff51bb828c5bde185a67f1d1ddf 354 Gene3D G3DSA:3.20.20.70 1 354 4.7E-149 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 VAPA_1c52880 05addff51bb828c5bde185a67f1d1ddf 354 TIGRFAM TIGR01521 FruBisAldo_II_B: fructose-bisphosphate aldolase, class II, Calvin cycle subtype 3 349 5.8E-183 T 12-10-2018 IPR006412 Fructose-bisphosphate aldolase, class II, Calvin cycle subtype GO:0004332|GO:0006096 KEGG: 00010+4.1.2.13|KEGG: 00030+4.1.2.13|KEGG: 00051+4.1.2.13|KEGG: 00680+4.1.2.13|KEGG: 00710+4.1.2.13|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 VAPA_1c52880 05addff51bb828c5bde185a67f1d1ddf 354 Pfam PF01116 Fructose-bisphosphate aldolase class-II 4 328 5.1E-95 T 12-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 VAPA_1c02000 55060c99112c778ea2ede86b5fac6c9c 416 Hamap MF_00372 Imidazolonepropionase [hutI]. 11 411 42.143 T 12-10-2018 IPR005920 Imidazolonepropionase GO:0005737|GO:0016812|GO:0019556 KEGG: 00340+3.5.2.7|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 VAPA_1c02000 55060c99112c778ea2ede86b5fac6c9c 416 SUPERFAMILY SSF51338 10 410 2.63E-19 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 VAPA_1c02000 55060c99112c778ea2ede86b5fac6c9c 416 SUPERFAMILY SSF51556 72 372 2.17E-89 T 12-10-2018 IPR032466 Metal-dependent hydrolase VAPA_1c02000 55060c99112c778ea2ede86b5fac6c9c 416 Gene3D G3DSA:2.30.40.10 33 408 3.6E-159 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 VAPA_1c02000 55060c99112c778ea2ede86b5fac6c9c 416 Gene3D G3DSA:3.20.20.140 73 371 3.6E-159 T 12-10-2018 VAPA_1c02000 55060c99112c778ea2ede86b5fac6c9c 416 Pfam PF01979 Amidohydrolase family 69 410 2.2E-18 T 12-10-2018 IPR006680 Amidohydrolase-related GO:0016787 VAPA_1c02000 55060c99112c778ea2ede86b5fac6c9c 416 TIGRFAM TIGR01224 hutI: imidazolonepropionase 34 410 3.1E-144 T 12-10-2018 IPR005920 Imidazolonepropionase GO:0005737|GO:0016812|GO:0019556 KEGG: 00340+3.5.2.7|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 VAPA_1c23400 38693a1a91b0ae91ca590b2fced8a2c3 904 TIGRFAM TIGR00759 aceE: pyruvate dehydrogenase (acetyl-transferring), homodimeric type 12 903 0.0 T 12-10-2018 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 VAPA_1c23400 38693a1a91b0ae91ca590b2fced8a2c3 904 Gene3D G3DSA:3.40.50.920 718 904 2.8E-72 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 VAPA_1c23400 38693a1a91b0ae91ca590b2fced8a2c3 904 SUPERFAMILY SSF52518 484 711 8.12E-94 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold VAPA_1c23400 38693a1a91b0ae91ca590b2fced8a2c3 904 SUPERFAMILY SSF52922 714 903 3.14E-58 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 VAPA_1c23400 38693a1a91b0ae91ca590b2fced8a2c3 904 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 372 436 1.2E-5 T 12-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 VAPA_1c23400 38693a1a91b0ae91ca590b2fced8a2c3 904 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 116 303 3.7E-9 T 12-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 VAPA_1c23400 38693a1a91b0ae91ca590b2fced8a2c3 904 Gene3D G3DSA:3.40.50.970 63 481 2.7E-134 T 12-10-2018 VAPA_1c23400 38693a1a91b0ae91ca590b2fced8a2c3 904 Gene3D G3DSA:3.40.50.970 482 717 1.7E-103 T 12-10-2018 VAPA_1c23400 38693a1a91b0ae91ca590b2fced8a2c3 904 SUPERFAMILY SSF52518 64 478 1.93E-136 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold VAPA_1c23400 38693a1a91b0ae91ca590b2fced8a2c3 904 PIRSF PIRSF000156 5 904 0.0 T 12-10-2018 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 VAPA_1c38000 c171594833ac0d473a954bf770376aa9 464 TIGRFAM TIGR02122 TRAP_TAXI: TRAP transporter solute receptor, TAXI family 25 292 5.2E-25 T 12-10-2018 IPR011852 TRAP transporter solute receptor, TAXI family VAPA_1c38000 c171594833ac0d473a954bf770376aa9 464 Pfam PF16868 NMT1-like family 49 291 5.9E-22 T 12-10-2018 IPR011852 TRAP transporter solute receptor, TAXI family VAPA_1c38000 c171594833ac0d473a954bf770376aa9 464 SUPERFAMILY SSF53850 43 293 1.54E-41 T 12-10-2018 VAPA_1c38000 c171594833ac0d473a954bf770376aa9 464 Gene3D G3DSA:3.40.190.10 123 266 2.3E-37 T 12-10-2018 VAPA_1c38000 c171594833ac0d473a954bf770376aa9 464 Gene3D G3DSA:3.40.190.10 49 305 2.3E-37 T 12-10-2018 VAPA_1c02670 618d95c425471cd9954cea3487e856b4 307 SUPERFAMILY SSF101898 15 267 9.42E-6 T 12-10-2018 VAPA_1c02670 618d95c425471cd9954cea3487e856b4 307 Pfam PF12275 Protein of unknown function (DUF3616) 148 271 4.5E-5 T 12-10-2018 IPR022060 Protein of unknown function DUF3616 VAPA_2c01620 dca877c268e2232d16d0e7e8953fe06e 294 Pfam PF12833 Helix-turn-helix domain 208 282 1.8E-20 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 VAPA_2c01620 dca877c268e2232d16d0e7e8953fe06e 294 SUPERFAMILY SSF46689 186 236 9.98E-11 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 VAPA_2c01620 dca877c268e2232d16d0e7e8953fe06e 294 Pfam PF06719 AraC-type transcriptional regulator N-terminus 24 173 1.5E-39 T 12-10-2018 IPR009594 Transcription regulator HTH, AraC, N-terminal VAPA_2c01620 dca877c268e2232d16d0e7e8953fe06e 294 Gene3D G3DSA:1.10.10.60 182 289 4.6E-25 T 12-10-2018 VAPA_2c01620 dca877c268e2232d16d0e7e8953fe06e 294 SMART SM00342 202 285 1.1E-22 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 VAPA_2c01620 dca877c268e2232d16d0e7e8953fe06e 294 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 239 281 - T 12-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 VAPA_2c01620 dca877c268e2232d16d0e7e8953fe06e 294 SUPERFAMILY SSF46689 238 284 1.34E-7 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 VAPA_2c06980 537ad40fdba8249b427c44a20418612f 394 Gene3D G3DSA:3.20.20.70 7 372 1.9E-112 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 VAPA_2c06980 537ad40fdba8249b427c44a20418612f 394 SUPERFAMILY SSF51395 6 355 7.79E-105 T 12-10-2018 VAPA_2c06980 537ad40fdba8249b427c44a20418612f 394 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 8 347 1.8E-61 T 12-10-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 VAPA_1c34990 56e72ad02172d3ac75c8ff29468479b6 497 SUPERFAMILY SSF56059 18 472 1.71E-64 T 12-10-2018 VAPA_1c34990 56e72ad02172d3ac75c8ff29468479b6 497 Gene3D G3DSA:3.40.50.11290 220 317 3.7E-43 T 12-10-2018 VAPA_1c34990 56e72ad02172d3ac75c8ff29468479b6 497 PIRSF PIRSF005522 1 484 1.6E-230 T 12-10-2018 IPR016450 Uncharacterised conserved protein UCP005522 VAPA_1c34990 56e72ad02172d3ac75c8ff29468479b6 497 Pfam PF14403 Circularly permuted ATP-grasp type 2 78 457 1.7E-163 T 12-10-2018 IPR025841 Circularly permuted ATP-grasp type 2 VAPA_1c34990 56e72ad02172d3ac75c8ff29468479b6 497 Gene3D G3DSA:3.30.1490.270 354 414 4.2E-25 T 12-10-2018 VAPA_1c17550 f7146f61a4f1777f07e5f3bb1247203f 221 Pfam PF02211 Nitrile hydratase beta subunit 7 219 1.4E-69 T 12-10-2018 IPR024690 Nitrile hydratase beta subunit domain GO:0018822 KEGG: 00364+4.2.1.84|KEGG: 00380+4.2.1.84|KEGG: 00627+4.2.1.84|KEGG: 00643+4.2.1.84|MetaCyc: PWY-5025|MetaCyc: PWY-581|MetaCyc: PWY-7308 VAPA_1c17550 f7146f61a4f1777f07e5f3bb1247203f 221 SUPERFAMILY SSF50090 7 220 4.32E-64 T 12-10-2018 IPR008990 Electron transport accessory-like domain superfamily VAPA_1c17550 f7146f61a4f1777f07e5f3bb1247203f 221 Gene3D G3DSA:2.30.30.50 123 221 3.7E-33 T 12-10-2018 VAPA_1c17550 f7146f61a4f1777f07e5f3bb1247203f 221 TIGRFAM TIGR03888 nitrile_beta: nitrile hydratase, beta subunit 7 220 4.9E-61 T 12-10-2018 IPR003168 Nitrile hydratase, beta subunit GO:0006807|GO:0018822|GO:0046914 KEGG: 00364+4.2.1.84|KEGG: 00380+4.2.1.84|KEGG: 00627+4.2.1.84|KEGG: 00643+4.2.1.84|MetaCyc: PWY-5025|MetaCyc: PWY-581|MetaCyc: PWY-7308 VAPA_1c17550 f7146f61a4f1777f07e5f3bb1247203f 221 Gene3D G3DSA:1.10.472.20 5 119 2.5E-28 T 12-10-2018 VAPA_1c17550 f7146f61a4f1777f07e5f3bb1247203f 221 PIRSF PIRSF001427 5 220 2.0E-52 T 12-10-2018 IPR003168 Nitrile hydratase, beta subunit GO:0006807|GO:0018822|GO:0046914 KEGG: 00364+4.2.1.84|KEGG: 00380+4.2.1.84|KEGG: 00627+4.2.1.84|KEGG: 00643+4.2.1.84|MetaCyc: PWY-5025|MetaCyc: PWY-581|MetaCyc: PWY-7308 VAPA_2c09100 41eb8a6320080e2444423fa24231a025 251 SUPERFAMILY SSF51735 1 210 1.71E-29 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_2c09100 41eb8a6320080e2444423fa24231a025 251 Gene3D G3DSA:3.40.50.720 2 246 5.6E-31 T 12-10-2018 VAPA_2c09100 41eb8a6320080e2444423fa24231a025 251 Pfam PF05368 NmrA-like family 3 172 9.9E-10 T 12-10-2018 IPR008030 NmrA-like domain Reactome: R-HSA-70635 VAPA_2c06260 e28a5b3f161e7b533468313d336c96be 392 SUPERFAMILY SSF49879 28 118 3.73E-8 T 12-10-2018 IPR008984 SMAD/FHA domain superfamily GO:0005515 VAPA_2c06260 e28a5b3f161e7b533468313d336c96be 392 Pfam PF16697 Inner membrane component of T3SS, cytoplasmic domain 31 120 3.9E-9 T 12-10-2018 IPR032030 YscD, cytoplasmic domain VAPA_2c06260 e28a5b3f161e7b533468313d336c96be 392 Gene3D G3DSA:2.60.200.20 25 140 3.5E-10 T 12-10-2018 VAPA_1c31620 783de1921cbee3b76f7d3c49453357ac 256 TIGRFAM TIGR01854 lipid_A_lpxH: UDP-2,3-diacylglucosamine diphosphatase 21 235 2.3E-61 T 12-10-2018 IPR010138 UDP-2,3-diacylglucosamine hydrolase GO:0005737|GO:0009245|GO:0016462 KEGG: 00540+3.6.1.54 VAPA_1c31620 783de1921cbee3b76f7d3c49453357ac 256 Pfam PF00149 Calcineurin-like phosphoesterase 18 214 1.0E-6 T 12-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 VAPA_1c31620 783de1921cbee3b76f7d3c49453357ac 256 Hamap MF_00575 UDP-2,3-diacylglucosamine hydrolase [lpxH]. 1 256 91.102 T 12-10-2018 IPR010138 UDP-2,3-diacylglucosamine hydrolase GO:0005737|GO:0009245|GO:0016462 KEGG: 00540+3.6.1.54 VAPA_1c31620 783de1921cbee3b76f7d3c49453357ac 256 SUPERFAMILY SSF56300 21 240 3.3E-28 T 12-10-2018 VAPA_2c11760 9b1c6fcc297ae9330b69a03fb606d076 409 Pfam PF00155 Aminotransferase class I and II 42 401 1.6E-69 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 VAPA_2c11760 9b1c6fcc297ae9330b69a03fb606d076 409 SUPERFAMILY SSF53383 12 407 1.33E-112 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase VAPA_2c11760 9b1c6fcc297ae9330b69a03fb606d076 409 Gene3D G3DSA:3.90.1150.10 35 401 1.2E-132 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 VAPA_2c11760 9b1c6fcc297ae9330b69a03fb606d076 409 Gene3D G3DSA:3.40.640.10 72 295 1.2E-132 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 VAPA_2c11760 9b1c6fcc297ae9330b69a03fb606d076 409 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 245 258 - T 12-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 VAPA_1c06840 f1839034de946d82fd59c26fd2590883 67 SUPERFAMILY SSF55331 1 58 3.52E-17 T 12-10-2018 IPR014347 Tautomerase/MIF superfamily VAPA_1c06840 f1839034de946d82fd59c26fd2590883 67 Pfam PF01361 Tautomerase enzyme 2 60 1.9E-14 T 12-10-2018 IPR004370 4-oxalocrotonate tautomerase GO:0006725|GO:0016853 VAPA_1c06840 f1839034de946d82fd59c26fd2590883 67 Gene3D G3DSA:3.30.429.10 1 61 6.2E-17 T 12-10-2018 IPR014347 Tautomerase/MIF superfamily VAPA_1c35900 803631730b3dab86bb227137eec68c23 610 SUPERFAMILY SSF56300 50 403 3.96E-63 T 12-10-2018 VAPA_1c35900 803631730b3dab86bb227137eec68c23 610 Pfam PF02872 5'-nucleotidase, C-terminal domain 410 574 7.6E-42 T 12-10-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 VAPA_1c35900 803631730b3dab86bb227137eec68c23 610 Pfam PF00149 Calcineurin-like phosphoesterase 58 314 2.4E-9 T 12-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 VAPA_1c35900 803631730b3dab86bb227137eec68c23 610 PRINTS PR01607 Apyrase family signature 547 566 4.7E-20 T 12-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 VAPA_1c35900 803631730b3dab86bb227137eec68c23 610 PRINTS PR01607 Apyrase family signature 262 279 4.7E-20 T 12-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 VAPA_1c35900 803631730b3dab86bb227137eec68c23 610 PRINTS PR01607 Apyrase family signature 55 73 4.7E-20 T 12-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 VAPA_1c35900 803631730b3dab86bb227137eec68c23 610 PRINTS PR01607 Apyrase family signature 297 320 4.7E-20 T 12-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 VAPA_1c35900 803631730b3dab86bb227137eec68c23 610 PRINTS PR01607 Apyrase family signature 329 349 4.7E-20 T 12-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 VAPA_1c35900 803631730b3dab86bb227137eec68c23 610 PRINTS PR01607 Apyrase family signature 471 494 4.7E-20 T 12-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 VAPA_1c35900 803631730b3dab86bb227137eec68c23 610 Gene3D G3DSA:3.90.780.10 415 608 2.2E-55 T 12-10-2018 IPR036907 5'-Nucleotidase, C-terminal domain superfamily GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 VAPA_1c35900 803631730b3dab86bb227137eec68c23 610 Gene3D G3DSA:3.60.21.10 48 382 3.5E-66 T 12-10-2018 IPR029052 Metallo-dependent phosphatase-like VAPA_1c35900 803631730b3dab86bb227137eec68c23 610 SUPERFAMILY SSF55816 408 609 3.53E-50 T 12-10-2018 IPR036907 5'-Nucleotidase, C-terminal domain superfamily GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 VAPA_1c32590 dce11b7c5f9a2e751a04c92cce9444c6 271 Gene3D G3DSA:3.40.50.720 11 270 4.5E-70 T 12-10-2018 VAPA_1c32590 dce11b7c5f9a2e751a04c92cce9444c6 271 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 34 268 7.2E-57 T 12-10-2018 VAPA_1c32590 dce11b7c5f9a2e751a04c92cce9444c6 271 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 28 209 4.7E-4 T 12-10-2018 VAPA_1c32590 dce11b7c5f9a2e751a04c92cce9444c6 271 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 158 166 1.5E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c32590 dce11b7c5f9a2e751a04c92cce9444c6 271 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 178 197 1.5E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c32590 dce11b7c5f9a2e751a04c92cce9444c6 271 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 103 114 1.5E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c32590 dce11b7c5f9a2e751a04c92cce9444c6 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 103 114 2.7E-29 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c32590 dce11b7c5f9a2e751a04c92cce9444c6 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 199 216 2.7E-29 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c32590 dce11b7c5f9a2e751a04c92cce9444c6 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 152 168 2.7E-29 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c32590 dce11b7c5f9a2e751a04c92cce9444c6 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 29 46 2.7E-29 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c32590 dce11b7c5f9a2e751a04c92cce9444c6 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 232 252 2.7E-29 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c32590 dce11b7c5f9a2e751a04c92cce9444c6 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 197 2.7E-29 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c32590 dce11b7c5f9a2e751a04c92cce9444c6 271 SUPERFAMILY SSF51735 27 270 1.59E-71 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c32590 dce11b7c5f9a2e751a04c92cce9444c6 271 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 165 193 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 VAPA_1c47090 ee7354e05ba3e831edbf39cb5d88c1d1 444 Pfam PF02321 Outer membrane efflux protein 249 413 7.4E-17 T 12-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 VAPA_1c47090 ee7354e05ba3e831edbf39cb5d88c1d1 444 Pfam PF02321 Outer membrane efflux protein 36 218 3.1E-24 T 12-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 VAPA_1c47090 ee7354e05ba3e831edbf39cb5d88c1d1 444 Gene3D G3DSA:1.20.1600.10 35 431 1.7E-63 T 12-10-2018 VAPA_1c47090 ee7354e05ba3e831edbf39cb5d88c1d1 444 TIGRFAM TIGR01844 type_I_sec_TolC: type I secretion outer membrane protein, TolC family 33 431 5.1E-74 T 12-10-2018 IPR010130 Type I secretion outer membrane protein, TolC GO:0015562|GO:0019867|GO:0055085 VAPA_1c47090 ee7354e05ba3e831edbf39cb5d88c1d1 444 SUPERFAMILY SSF56954 6 426 3.27E-64 T 12-10-2018 VAPA_1c12200 53fb1959662c2cf1d8fb5b56b0f4c18f 254 PRINTS PR00164 ABC-2 type transport system membrane protein signature 194 213 1.7E-9 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 VAPA_1c12200 53fb1959662c2cf1d8fb5b56b0f4c18f 254 PRINTS PR00164 ABC-2 type transport system membrane protein signature 56 78 1.7E-9 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 VAPA_1c12200 53fb1959662c2cf1d8fb5b56b0f4c18f 254 PRINTS PR00164 ABC-2 type transport system membrane protein signature 174 193 1.7E-9 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 VAPA_1c12200 53fb1959662c2cf1d8fb5b56b0f4c18f 254 Pfam PF01061 ABC-2 type transporter 7 217 3.1E-34 T 12-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 VAPA_1c12200 53fb1959662c2cf1d8fb5b56b0f4c18f 254 PIRSF PIRSF006648 7 251 2.5E-19 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 VAPA_1c33280 a06ae02861017c98f1d9a92a9c55ac99 331 SMART SM01092 229 327 1.7E-25 T 12-10-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal VAPA_1c33280 a06ae02861017c98f1d9a92a9c55ac99 331 Gene3D G3DSA:3.30.390.50 227 330 1.4E-25 T 12-10-2018 VAPA_1c33280 a06ae02861017c98f1d9a92a9c55ac99 331 SUPERFAMILY SSF56176 1 222 1.58E-59 T 12-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 VAPA_1c33280 a06ae02861017c98f1d9a92a9c55ac99 331 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 3 222 1.9E-49 T 12-10-2018 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 VAPA_1c33280 a06ae02861017c98f1d9a92a9c55ac99 331 Pfam PF03450 CO dehydrogenase flavoprotein C-terminal domain 230 312 1.1E-17 T 12-10-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal VAPA_1c33280 a06ae02861017c98f1d9a92a9c55ac99 331 SUPERFAMILY SSF55447 227 329 6.8E-26 T 12-10-2018 IPR036683 CO dehydrogenase flavoprotein, C-terminal domain superfamily VAPA_1c33280 a06ae02861017c98f1d9a92a9c55ac99 331 Gene3D G3DSA:3.30.465.10 1 223 2.9E-80 T 12-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 VAPA_1c48500 03e5650e87509c1f8a46d51baf54b688 364 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_1c48500 03e5650e87509c1f8a46d51baf54b688 364 TIGRFAM TIGR01187 potA: polyamine ABC transporter, ATP-binding protein 38 359 7.0E-110 T 12-10-2018 IPR005893 Spermidine/putrescine ABC transporter, ATP-binding subunit GO:0015417|GO:0015846|GO:0043190 VAPA_1c48500 03e5650e87509c1f8a46d51baf54b688 364 SUPERFAMILY SSF50331 249 361 4.53E-11 T 12-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal VAPA_1c48500 03e5650e87509c1f8a46d51baf54b688 364 Pfam PF00005 ABC transporter 24 165 2.5E-34 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c48500 03e5650e87509c1f8a46d51baf54b688 364 Gene3D G3DSA:3.40.50.300 6 226 4.6E-64 T 12-10-2018 VAPA_1c48500 03e5650e87509c1f8a46d51baf54b688 364 SMART SM00382 32 215 2.7E-16 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c48500 03e5650e87509c1f8a46d51baf54b688 364 Gene3D G3DSA:2.40.50.940 227 362 1.0E-9 T 12-10-2018 VAPA_1c48500 03e5650e87509c1f8a46d51baf54b688 364 Pfam PF08402 TOBE domain 282 360 3.6E-13 T 12-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 VAPA_1c48500 03e5650e87509c1f8a46d51baf54b688 364 Gene3D G3DSA:2.40.50.140 288 354 1.0E-9 T 12-10-2018 VAPA_1c48500 03e5650e87509c1f8a46d51baf54b688 364 SUPERFAMILY SSF52540 6 243 2.46E-86 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c07150 5ddb42f06a1f8b0dd7be9235cd2cd298 305 SUPERFAMILY SSF46785 4 89 1.52E-23 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c07150 5ddb42f06a1f8b0dd7be9235cd2cd298 305 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 65 3.8E-20 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c07150 5ddb42f06a1f8b0dd7be9235cd2cd298 305 Gene3D G3DSA:1.10.10.10 4 94 5.9E-30 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c07150 5ddb42f06a1f8b0dd7be9235cd2cd298 305 Pfam PF03466 LysR substrate binding domain 90 294 6.8E-36 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_1c07150 5ddb42f06a1f8b0dd7be9235cd2cd298 305 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 32 42 7.1E-10 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c07150 5ddb42f06a1f8b0dd7be9235cd2cd298 305 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 21 32 7.1E-10 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c07150 5ddb42f06a1f8b0dd7be9235cd2cd298 305 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 53 7.1E-10 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c07150 5ddb42f06a1f8b0dd7be9235cd2cd298 305 Gene3D G3DSA:3.40.190.10 165 269 1.1E-48 T 12-10-2018 VAPA_1c07150 5ddb42f06a1f8b0dd7be9235cd2cd298 305 Gene3D G3DSA:3.40.190.10 95 287 1.1E-48 T 12-10-2018 VAPA_1c07150 5ddb42f06a1f8b0dd7be9235cd2cd298 305 SUPERFAMILY SSF53850 91 298 3.14E-33 T 12-10-2018 VAPA_1c40480 3a8b50d60f2f6f153c30cb45e816db86 268 Pfam PF13478 XdhC Rossmann domain 117 263 6.0E-34 T 12-10-2018 IPR027051 XdhC Rossmann domain VAPA_1c40480 3a8b50d60f2f6f153c30cb45e816db86 268 Pfam PF02625 XdhC and CoxI family 13 77 5.0E-18 T 12-10-2018 IPR003777 XdhC- CoxI VAPA_1c40480 3a8b50d60f2f6f153c30cb45e816db86 268 SUPERFAMILY SSF51735 88 199 4.43E-5 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c40480 3a8b50d60f2f6f153c30cb45e816db86 268 TIGRFAM TIGR02964 xanthine_xdhC: xanthine dehydrogenase accessory protein XdhC 18 264 1.8E-86 T 12-10-2018 IPR014308 Xanthine dehydrogenase accessory protein XdhC VAPA_1c40480 3a8b50d60f2f6f153c30cb45e816db86 268 Gene3D G3DSA:3.40.50.720 117 267 2.7E-31 T 12-10-2018 VAPA_1c48760 674a8b70b58785d08c6b30aa0cd98c67 543 SUPERFAMILY SSF52096 22 273 5.46E-71 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily VAPA_1c48760 674a8b70b58785d08c6b30aa0cd98c67 543 Gene3D G3DSA:3.90.226.10 1 276 4.6E-95 T 12-10-2018 VAPA_1c48760 674a8b70b58785d08c6b30aa0cd98c67 543 Pfam PF01039 Carboxyl transferase domain 48 533 1.6E-150 T 12-10-2018 IPR034733 Acetyl-CoA carboxylase MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722|Reactome: R-HSA-196780 VAPA_1c48760 674a8b70b58785d08c6b30aa0cd98c67 543 SUPERFAMILY SSF52096 285 543 7.04E-87 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily VAPA_1c48760 674a8b70b58785d08c6b30aa0cd98c67 543 Gene3D G3DSA:3.90.226.10 280 543 3.0E-103 T 12-10-2018 VAPA_1c16350 bf545679d76d037d11fb8e031e1d4e79 348 Pfam PF01636 Phosphotransferase enzyme family 27 276 2.1E-31 T 12-10-2018 IPR002575 Aminoglycoside phosphotransferase VAPA_1c16350 bf545679d76d037d11fb8e031e1d4e79 348 SUPERFAMILY SSF56112 7 332 6.85E-67 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily VAPA_1c16350 bf545679d76d037d11fb8e031e1d4e79 348 Hamap MF_00301 Homoserine kinase [thrB]. 1 348 149.156 T 12-10-2018 IPR005280 Homoserine kinase, type II GO:0004413|GO:0009088 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 VAPA_1c16350 bf545679d76d037d11fb8e031e1d4e79 348 Gene3D G3DSA:3.90.1200.10 121 338 8.5E-70 T 12-10-2018 VAPA_1c16350 bf545679d76d037d11fb8e031e1d4e79 348 TIGRFAM TIGR00938 thrB_alt: homoserine kinase 1 330 6.9E-84 T 12-10-2018 IPR005280 Homoserine kinase, type II GO:0004413|GO:0009088 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 VAPA_1c16350 bf545679d76d037d11fb8e031e1d4e79 348 Gene3D G3DSA:3.30.200.20 1 89 6.6E-25 T 12-10-2018 VAPA_2c10450 81082e1993937441f732d92a1f0c4199 355 Pfam PF00465 Iron-containing alcohol dehydrogenase 10 334 2.6E-78 T 12-10-2018 IPR001670 Alcohol dehydrogenase, iron-type/glycerol dehydrogenase GldA GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 VAPA_2c10450 81082e1993937441f732d92a1f0c4199 355 Gene3D G3DSA:1.20.1090.10 161 355 1.8E-58 T 12-10-2018 VAPA_2c10450 81082e1993937441f732d92a1f0c4199 355 SUPERFAMILY SSF56796 8 351 1.44E-89 T 12-10-2018 VAPA_2c10450 81082e1993937441f732d92a1f0c4199 355 Gene3D G3DSA:3.40.50.1970 1 160 2.5E-48 T 12-10-2018 VAPA_1c16650 b951eb98b8f1643161ed9755676b8008 305 SUPERFAMILY SSF48576 18 288 4.11E-82 T 12-10-2018 IPR008949 Isoprenoid synthase domain superfamily VAPA_1c16650 b951eb98b8f1643161ed9755676b8008 305 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 90 106 - T 12-10-2018 IPR033749 Polyprenyl synthetase, conserved site VAPA_1c16650 b951eb98b8f1643161ed9755676b8008 305 Gene3D G3DSA:1.10.600.10 9 305 8.8E-93 T 12-10-2018 IPR008949 Isoprenoid synthase domain superfamily VAPA_1c16650 b951eb98b8f1643161ed9755676b8008 305 Pfam PF00348 Polyprenyl synthetase 41 279 2.1E-56 T 12-10-2018 IPR000092 Polyprenyl synthetase GO:0008299 VAPA_1c16650 b951eb98b8f1643161ed9755676b8008 305 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 223 235 - T 12-10-2018 IPR033749 Polyprenyl synthetase, conserved site VAPA_1c02430 a1dd627369309d4a1fd9c4b34ddfe9ba 641 Gene3D G3DSA:2.60.200.20 16 102 3.3E-11 T 12-10-2018 VAPA_1c02430 a1dd627369309d4a1fd9c4b34ddfe9ba 641 SUPERFAMILY SSF49879 16 100 7.46E-13 T 12-10-2018 IPR008984 SMAD/FHA domain superfamily GO:0005515 VAPA_1c02430 a1dd627369309d4a1fd9c4b34ddfe9ba 641 TIGRFAM TIGR03354 VI_FHA: type VI secretion system FHA domain protein 352 631 3.2E-48 T 12-10-2018 IPR017735 Type VI secretion system, FHA domain-containing protein VAPA_1c02430 a1dd627369309d4a1fd9c4b34ddfe9ba 641 Pfam PF00498 FHA domain 27 95 1.4E-7 T 12-10-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 VAPA_1c26900 cac316d865bff089307ab7edde8a1bad 781 Gene3D G3DSA:3.55.50.10 95 185 2.8E-113 T 12-10-2018 VAPA_1c26900 cac316d865bff089307ab7edde8a1bad 781 SUPERFAMILY SSF69279 187 360 1.87E-45 T 12-10-2018 VAPA_1c26900 cac316d865bff089307ab7edde8a1bad 781 SUPERFAMILY SSF69349 437 643 1.26E-36 T 12-10-2018 VAPA_1c26900 cac316d865bff089307ab7edde8a1bad 781 SUPERFAMILY SSF69279 7 181 2.15E-56 T 12-10-2018 VAPA_1c26900 cac316d865bff089307ab7edde8a1bad 781 Gene3D G3DSA:2.40.50.230 351 451 1.1E-42 T 12-10-2018 IPR037026 Vgr protein, OB-fold domain superfamily VAPA_1c26900 cac316d865bff089307ab7edde8a1bad 781 Gene3D G3DSA:3.30.1920.30 221 283 2.8E-113 T 12-10-2018 VAPA_1c26900 cac316d865bff089307ab7edde8a1bad 781 Pfam PF05954 Phage late control gene D protein (GPD) 24 325 1.1E-96 T 12-10-2018 VAPA_1c26900 cac316d865bff089307ab7edde8a1bad 781 Gene3D G3DSA:2.30.110.50 9 329 2.8E-113 T 12-10-2018 VAPA_1c26900 cac316d865bff089307ab7edde8a1bad 781 TIGRFAM TIGR03361 VI_Rhs_Vgr: type VI secretion system Vgr family protein 6 516 3.5E-186 T 12-10-2018 IPR017847 Type VI secretion system, RhsGE-associated Vgr family subset VAPA_1c26900 cac316d865bff089307ab7edde8a1bad 781 TIGRFAM TIGR01646 vgr_GE: Rhs element Vgr protein 20 500 1.2E-142 T 12-10-2018 IPR006533 Type VI secretion system, RhsGE-associated Vgr protein VAPA_1c26900 cac316d865bff089307ab7edde8a1bad 781 SUPERFAMILY SSF69255 360 446 8.11E-31 T 12-10-2018 VAPA_1c04260 1120e3ec901e3ad371e5618b39711cbc 238 SUPERFAMILY SSF46785 3 78 7.18E-18 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c04260 1120e3ec901e3ad371e5618b39711cbc 238 Pfam PF07729 FCD domain 78 205 7.0E-17 T 12-10-2018 IPR011711 GntR, C-terminal VAPA_1c04260 1120e3ec901e3ad371e5618b39711cbc 238 SMART SM00895 76 207 4.0E-19 T 12-10-2018 IPR011711 GntR, C-terminal VAPA_1c04260 1120e3ec901e3ad371e5618b39711cbc 238 SMART SM00345 8 66 3.0E-12 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_1c04260 1120e3ec901e3ad371e5618b39711cbc 238 Pfam PF00392 Bacterial regulatory proteins, gntR family 4 66 8.3E-15 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_1c04260 1120e3ec901e3ad371e5618b39711cbc 238 SUPERFAMILY SSF48008 72 208 2.54E-20 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal VAPA_1c04260 1120e3ec901e3ad371e5618b39711cbc 238 Gene3D G3DSA:1.10.10.10 1 67 4.1E-21 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c04260 1120e3ec901e3ad371e5618b39711cbc 238 Gene3D G3DSA:1.20.120.530 77 212 2.9E-22 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal VAPA_1c00230 847860adfdb5c6d12d563611d9b473d8 493 Pfam PF06123 Inner membrane protein CreD 12 472 3.6E-131 T 12-10-2018 IPR010364 Uncharacterised protein family, inner membrane CreD VAPA_1c00230 847860adfdb5c6d12d563611d9b473d8 493 PIRSF PIRSF004548 3 484 6.8E-122 T 12-10-2018 IPR010364 Uncharacterised protein family, inner membrane CreD VAPA_2c00030 ed79aebe169bfb74b92ff99cca09fdd3 323 Gene3D G3DSA:1.10.10.60 214 319 6.5E-27 T 12-10-2018 VAPA_2c00030 ed79aebe169bfb74b92ff99cca09fdd3 323 SUPERFAMILY SSF52317 1 189 2.2E-7 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like VAPA_2c00030 ed79aebe169bfb74b92ff99cca09fdd3 323 SUPERFAMILY SSF46689 264 315 9.68E-12 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 VAPA_2c00030 ed79aebe169bfb74b92ff99cca09fdd3 323 SUPERFAMILY SSF46689 211 259 2.54E-8 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 VAPA_2c00030 ed79aebe169bfb74b92ff99cca09fdd3 323 SMART SM00342 228 311 4.4E-23 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 VAPA_2c00030 ed79aebe169bfb74b92ff99cca09fdd3 323 Gene3D G3DSA:3.40.50.880 1 119 2.0E-9 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like VAPA_2c00030 ed79aebe169bfb74b92ff99cca09fdd3 323 Pfam PF12833 Helix-turn-helix domain 234 313 2.4E-20 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 VAPA_1c54780 44e8a123f2426025a2f509e8b23d3dc3 492 Pfam PF13785 Domain of unknown function (DUF4178) 278 415 2.5E-26 T 12-10-2018 IPR025235 Domain of unknown function DUF4178 VAPA_1c54780 44e8a123f2426025a2f509e8b23d3dc3 492 Pfam PF13785 Domain of unknown function (DUF4178) 69 203 2.4E-16 T 12-10-2018 IPR025235 Domain of unknown function DUF4178 VAPA_2c08560 2627d92ecf476ca82181c0d51760dbe4 716 Gene3D G3DSA:3.30.450.40 23 209 1.3E-54 T 12-10-2018 IPR029016 GAF-like domain superfamily VAPA_2c08560 2627d92ecf476ca82181c0d51760dbe4 716 SMART SM00382 389 533 2.8E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_2c08560 2627d92ecf476ca82181c0d51760dbe4 716 SUPERFAMILY SSF52540 375 602 9.63E-58 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_2c08560 2627d92ecf476ca82181c0d51760dbe4 716 Gene3D G3DSA:3.40.50.300 366 541 8.5E-58 T 12-10-2018 VAPA_2c08560 2627d92ecf476ca82181c0d51760dbe4 716 Gene3D G3DSA:1.10.8.60 542 619 2.3E-9 T 12-10-2018 VAPA_2c08560 2627d92ecf476ca82181c0d51760dbe4 716 SUPERFAMILY SSF55781 65 205 1.02E-5 T 12-10-2018 VAPA_2c08560 2627d92ecf476ca82181c0d51760dbe4 716 Pfam PF01590 GAF domain 86 206 6.9E-8 T 12-10-2018 IPR003018 GAF domain GO:0005515 VAPA_2c08560 2627d92ecf476ca82181c0d51760dbe4 716 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 393 406 - T 12-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 VAPA_2c08560 2627d92ecf476ca82181c0d51760dbe4 716 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 456 471 - T 12-10-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 VAPA_2c08560 2627d92ecf476ca82181c0d51760dbe4 716 Gene3D G3DSA:1.10.10.60 660 713 4.7E-13 T 12-10-2018 VAPA_2c08560 2627d92ecf476ca82181c0d51760dbe4 716 SUPERFAMILY SSF46689 580 711 5.73E-11 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 VAPA_2c08560 2627d92ecf476ca82181c0d51760dbe4 716 Pfam PF02954 Bacterial regulatory protein, Fis family 673 711 7.3E-11 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 VAPA_2c08560 2627d92ecf476ca82181c0d51760dbe4 716 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 579 588 - T 12-10-2018 IPR025944 Sigma-54 interaction domain, conserved site VAPA_2c08560 2627d92ecf476ca82181c0d51760dbe4 716 Pfam PF00158 Sigma-54 interaction domain 373 534 8.3E-65 T 12-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 VAPA_1c13800 f6dc74986cc3c87da255dbd06ed4e151 295 SUPERFAMILY SSF53850 90 291 1.27E-41 T 12-10-2018 VAPA_1c13800 f6dc74986cc3c87da255dbd06ed4e151 295 Gene3D G3DSA:1.10.10.10 3 90 8.7E-21 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c13800 f6dc74986cc3c87da255dbd06ed4e151 295 Pfam PF03466 LysR substrate binding domain 89 292 1.4E-39 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_1c13800 f6dc74986cc3c87da255dbd06ed4e151 295 SUPERFAMILY SSF46785 3 112 2.34E-21 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c13800 f6dc74986cc3c87da255dbd06ed4e151 295 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 5.0E-17 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c13800 f6dc74986cc3c87da255dbd06ed4e151 295 Gene3D G3DSA:3.40.190.290 93 293 2.3E-39 T 12-10-2018 VAPA_1c14480 c4278873bbca1bdf2ec317def8dcf497 197 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 30 192 8.5E-29 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 VAPA_1c14480 c4278873bbca1bdf2ec317def8dcf497 197 Gene3D G3DSA:1.10.10.10 103 195 3.5E-27 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c14480 c4278873bbca1bdf2ec317def8dcf497 197 Pfam PF04542 Sigma-70 region 2 34 101 7.7E-15 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 VAPA_1c14480 c4278873bbca1bdf2ec317def8dcf497 197 SUPERFAMILY SSF88946 11 117 1.2E-21 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 VAPA_1c14480 c4278873bbca1bdf2ec317def8dcf497 197 Gene3D G3DSA:1.10.1740.10 15 98 1.2E-23 T 12-10-2018 VAPA_1c14480 c4278873bbca1bdf2ec317def8dcf497 197 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 56 88 - T 12-10-2018 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 VAPA_1c14480 c4278873bbca1bdf2ec317def8dcf497 197 Pfam PF08281 Sigma-70, region 4 138 189 3.1E-15 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 VAPA_1c14480 c4278873bbca1bdf2ec317def8dcf497 197 SUPERFAMILY SSF88659 114 194 9.53E-17 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like VAPA_1c34450 81f09f789a32ca175ddcffb1173b6eee 334 Gene3D G3DSA:3.40.50.2300 132 276 7.6E-70 T 12-10-2018 VAPA_1c34450 81f09f789a32ca175ddcffb1173b6eee 334 Gene3D G3DSA:3.40.50.2300 30 294 7.6E-70 T 12-10-2018 VAPA_1c34450 81f09f789a32ca175ddcffb1173b6eee 334 SUPERFAMILY SSF53822 28 312 7.46E-65 T 12-10-2018 IPR028082 Periplasmic binding protein-like I VAPA_1c34450 81f09f789a32ca175ddcffb1173b6eee 334 Pfam PF13407 Periplasmic binding protein domain 29 297 1.5E-47 T 12-10-2018 IPR025997 Periplasmic binding protein VAPA_1c34720 8f7c0a32f84df0d9d4585c65fc5205c7 306 Gene3D G3DSA:3.40.50.300 18 183 8.9E-45 T 12-10-2018 VAPA_1c34720 8f7c0a32f84df0d9d4585c65fc5205c7 306 SMART SM00382 34 175 0.0025 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c34720 8f7c0a32f84df0d9d4585c65fc5205c7 306 SUPERFAMILY SSF52540 8 281 3.43E-43 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c34720 8f7c0a32f84df0d9d4585c65fc5205c7 306 Gene3D G3DSA:1.10.8.300 198 303 1.1E-23 T 12-10-2018 VAPA_1c34720 8f7c0a32f84df0d9d4585c65fc5205c7 306 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 37 167 7.7E-61 T 12-10-2018 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 VAPA_1c34720 8f7c0a32f84df0d9d4585c65fc5205c7 306 PIRSF PIRSF002849 1 306 1.2E-118 T 12-10-2018 VAPA_2c04520 aaa7da97d079826447a29fd29b4164cf 228 TIGRFAM TIGR00684 narJ: nitrate reductase molybdenum cofactor assembly chaperone 14 165 9.5E-34 T 12-10-2018 IPR003765 Nitrate reductase chaperone, NarJ GO:0051082|GO:0051131 VAPA_2c04520 aaa7da97d079826447a29fd29b4164cf 228 Gene3D G3DSA:1.10.3480.10 2 172 2.0E-10 T 12-10-2018 VAPA_2c04520 aaa7da97d079826447a29fd29b4164cf 228 SUPERFAMILY SSF89155 8 168 1.22E-30 T 12-10-2018 IPR036411 TorD-like superfamily VAPA_2c04520 aaa7da97d079826447a29fd29b4164cf 228 Pfam PF02613 Nitrate reductase delta subunit 38 130 7.3E-11 T 12-10-2018 IPR020945 DMSO/Nitrate reductase chaperone VAPA_1c49540 6dd3a6f13a5329ea79d32deb249df96a 444 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 251 288 - T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 VAPA_1c49540 6dd3a6f13a5329ea79d32deb249df96a 444 Gene3D G3DSA:3.90.1150.10 23 435 4.6E-139 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 VAPA_1c49540 6dd3a6f13a5329ea79d32deb249df96a 444 PIRSF PIRSF000521 36 443 1.6E-25 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 VAPA_1c49540 6dd3a6f13a5329ea79d32deb249df96a 444 Gene3D G3DSA:3.40.640.10 60 345 4.6E-139 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 VAPA_1c49540 6dd3a6f13a5329ea79d32deb249df96a 444 Pfam PF00202 Aminotransferase class-III 27 439 1.7E-89 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 VAPA_1c49540 6dd3a6f13a5329ea79d32deb249df96a 444 SUPERFAMILY SSF53383 11 441 1.14E-115 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase VAPA_2c10460 1d75bea84f12a5ffa2592f71f9991255 324 SUPERFAMILY SSF53850 111 287 1.41E-8 T 12-10-2018 VAPA_2c10460 1d75bea84f12a5ffa2592f71f9991255 324 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 48 321 8.3E-96 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_2c10460 1d75bea84f12a5ffa2592f71f9991255 324 PIRSF PIRSF017082 1 323 1.7E-79 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_2c10460 1d75bea84f12a5ffa2592f71f9991255 324 Gene3D G3DSA:3.40.190.10 126 249 2.5E-111 T 12-10-2018 VAPA_2c10460 1d75bea84f12a5ffa2592f71f9991255 324 Gene3D G3DSA:3.40.190.150 29 314 2.5E-111 T 12-10-2018 VAPA_1c18210 a76c796d8fbc55614cc24b7e1f99ba88 478 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 274 285 - T 12-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 VAPA_1c18210 a76c796d8fbc55614cc24b7e1f99ba88 478 Pfam PF00171 Aldehyde dehydrogenase family 18 473 6.2E-158 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 VAPA_1c18210 a76c796d8fbc55614cc24b7e1f99ba88 478 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 246 253 - T 12-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 VAPA_1c18210 a76c796d8fbc55614cc24b7e1f99ba88 478 Gene3D G3DSA:3.40.309.10 251 443 1.6E-154 T 12-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 VAPA_1c18210 a76c796d8fbc55614cc24b7e1f99ba88 478 SUPERFAMILY SSF53720 2 474 3.8E-154 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 VAPA_1c18210 a76c796d8fbc55614cc24b7e1f99ba88 478 Gene3D G3DSA:3.40.605.10 8 472 1.6E-154 T 12-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 VAPA_1c31070 ec7d6f3aa7d4257b041c71af2a496c93 134 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 45 117 3.9E-10 T 12-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 VAPA_1c31070 ec7d6f3aa7d4257b041c71af2a496c93 134 Gene3D G3DSA:1.10.760.10 31 134 2.4E-10 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 VAPA_1c31070 ec7d6f3aa7d4257b041c71af2a496c93 134 SUPERFAMILY SSF46626 9 123 1.77E-14 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 VAPA_1c08140 f44539cbe50cb3f984a62150888e181c 360 Pfam PF16363 GDP-mannose 4,6 dehydratase 3 323 2.3E-100 T 12-10-2018 IPR016040 NAD(P)-binding domain VAPA_1c08140 f44539cbe50cb3f984a62150888e181c 360 Gene3D G3DSA:3.40.50.720 2 322 2.2E-130 T 12-10-2018 VAPA_1c08140 f44539cbe50cb3f984a62150888e181c 360 TIGRFAM TIGR01181 dTDP_gluc_dehyt: dTDP-glucose 4,6-dehydratase 2 337 7.8E-153 T 12-10-2018 IPR005888 dTDP-glucose 4,6-dehydratase GO:0008460|GO:0009225 KEGG: 00521+4.2.1.46|KEGG: 00523+4.2.1.46|KEGG: 00525+4.2.1.46|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688|MetaCyc: PWY-7814 VAPA_1c08140 f44539cbe50cb3f984a62150888e181c 360 Gene3D G3DSA:3.90.25.10 200 330 2.2E-130 T 12-10-2018 VAPA_1c08140 f44539cbe50cb3f984a62150888e181c 360 SUPERFAMILY SSF51735 2 335 2.11E-89 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c22490 cee1e1e5e4ada5526907aea1348441f5 96 Gene3D G3DSA:3.20.20.70 1 88 8.4E-15 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 VAPA_1c22490 cee1e1e5e4ada5526907aea1348441f5 96 Pfam PF01070 FMN-dependent dehydrogenase 12 84 1.6E-11 T 12-10-2018 IPR000262 FMN-dependent dehydrogenase GO:0016491 Reactome: R-HSA-9033241 VAPA_1c22490 cee1e1e5e4ada5526907aea1348441f5 96 SUPERFAMILY SSF51395 3 83 2.12E-10 T 12-10-2018 VAPA_1c13060 661fdfef34b44e202b2854973515f95b 218 Gene3D G3DSA:1.10.357.10 55 196 1.1E-28 T 12-10-2018 VAPA_1c13060 661fdfef34b44e202b2854973515f95b 218 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 37 60 1.4E-9 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 VAPA_1c13060 661fdfef34b44e202b2854973515f95b 218 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 16 29 1.4E-9 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 VAPA_1c13060 661fdfef34b44e202b2854973515f95b 218 SUPERFAMILY SSF48498 85 194 2.67E-11 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily VAPA_1c13060 661fdfef34b44e202b2854973515f95b 218 SUPERFAMILY SSF46689 2 87 7.48E-19 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 VAPA_1c13060 661fdfef34b44e202b2854973515f95b 218 Gene3D G3DSA:1.10.10.60 1 53 3.4E-21 T 12-10-2018 VAPA_1c13060 661fdfef34b44e202b2854973515f95b 218 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 61 4.0E-16 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 VAPA_1c21090 604a984f8970013ae18222af5b49187a 632 TIGRFAM TIGR01515 branching_enzym: 1,4-alpha-glucan branching enzyme 14 627 1.7E-271 T 12-10-2018 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|MetaCyc: PWY-7900 VAPA_1c21090 604a984f8970013ae18222af5b49187a 632 SUPERFAMILY SSF51011 527 629 6.47E-31 T 12-10-2018 VAPA_1c21090 604a984f8970013ae18222af5b49187a 632 SMART SM00642 154 509 1.0E-7 T 12-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 VAPA_1c21090 604a984f8970013ae18222af5b49187a 632 Gene3D G3DSA:2.60.40.1180 526 630 3.4E-35 T 12-10-2018 IPR013780 Glycosyl hydrolase, all-beta VAPA_1c21090 604a984f8970013ae18222af5b49187a 632 Gene3D G3DSA:2.60.40.10 5 125 1.1E-36 T 12-10-2018 IPR013783 Immunoglobulin-like fold VAPA_1c21090 604a984f8970013ae18222af5b49187a 632 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 30 111 1.1E-17 T 12-10-2018 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 VAPA_1c21090 604a984f8970013ae18222af5b49187a 632 PIRSF PIRSF000463 3 632 3.2E-275 T 12-10-2018 IPR037439 1,4-alpha-glucan-branching enzyme GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|MetaCyc: PWY-7900|Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 VAPA_1c21090 604a984f8970013ae18222af5b49187a 632 SUPERFAMILY SSF81296 21 131 5.25E-25 T 12-10-2018 IPR014756 Immunoglobulin E-set VAPA_1c21090 604a984f8970013ae18222af5b49187a 632 Pfam PF00128 Alpha amylase, catalytic domain 180 250 2.4E-10 T 12-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 VAPA_1c21090 604a984f8970013ae18222af5b49187a 632 Gene3D G3DSA:3.20.20.80 128 525 5.4E-165 T 12-10-2018 VAPA_1c21090 604a984f8970013ae18222af5b49187a 632 Pfam PF02806 Alpha amylase, C-terminal all-beta domain 531 629 1.5E-19 T 12-10-2018 IPR006048 Alpha-amylase/branching enzyme, C-terminal all beta GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|MetaCyc: PWY-7900 VAPA_1c21090 604a984f8970013ae18222af5b49187a 632 SUPERFAMILY SSF51445 82 519 3.25E-109 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily VAPA_1c21090 604a984f8970013ae18222af5b49187a 632 Hamap MF_00685 1,4-alpha-glucan branching enzyme GlgB [glgB]. 4 630 43.978 T 12-10-2018 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|MetaCyc: PWY-7900 VAPA_2c09760 f9e966fe8be1ebea6459a3a88193dd33 443 Gene3D G3DSA:3.30.1120.10 356 409 1.7E-109 T 12-10-2018 VAPA_2c09760 f9e966fe8be1ebea6459a3a88193dd33 443 Pfam PF00884 Sulfatase 7 329 5.0E-66 T 12-10-2018 IPR000917 Sulfatase, N-terminal GO:0008484 VAPA_2c09760 f9e966fe8be1ebea6459a3a88193dd33 443 Gene3D G3DSA:3.40.720.10 7 355 1.7E-109 T 12-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 VAPA_2c09760 f9e966fe8be1ebea6459a3a88193dd33 443 Pfam PF14707 C-terminal region of aryl-sulfatase 353 436 3.0E-9 T 12-10-2018 VAPA_2c09760 f9e966fe8be1ebea6459a3a88193dd33 443 SUPERFAMILY SSF53649 7 440 3.34E-117 T 12-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 VAPA_2c11260 d1aa4236925fa92e08549e30e16fe64e 307 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 2.2E-19 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_2c11260 d1aa4236925fa92e08549e30e16fe64e 307 SUPERFAMILY SSF46785 1 86 3.38E-23 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_2c11260 d1aa4236925fa92e08549e30e16fe64e 307 Pfam PF03466 LysR substrate binding domain 87 293 1.1E-36 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_2c11260 d1aa4236925fa92e08549e30e16fe64e 307 Gene3D G3DSA:1.10.10.10 1 89 7.7E-29 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_2c11260 d1aa4236925fa92e08549e30e16fe64e 307 SUPERFAMILY SSF53850 89 297 9.46E-34 T 12-10-2018 VAPA_2c11260 d1aa4236925fa92e08549e30e16fe64e 307 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 4.9E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_2c11260 d1aa4236925fa92e08549e30e16fe64e 307 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 4.9E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_2c11260 d1aa4236925fa92e08549e30e16fe64e 307 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 4.9E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_2c11260 d1aa4236925fa92e08549e30e16fe64e 307 Gene3D G3DSA:3.40.190.290 91 300 4.7E-38 T 12-10-2018 VAPA_1c28020 60ee9dfac1e7ebfe1c84749466bc17b7 126 PIRSF PIRSF029720 3 126 2.2E-45 T 12-10-2018 IPR014558 Uncharacterised conserved lipoprotein VAPA_1c28020 60ee9dfac1e7ebfe1c84749466bc17b7 126 Pfam PF03640 Secreted repeat of unknown function 82 125 3.1E-19 T 12-10-2018 IPR005297 Lipoprotein repeat VAPA_1c28020 60ee9dfac1e7ebfe1c84749466bc17b7 126 Pfam PF03640 Secreted repeat of unknown function 30 70 1.0E-14 T 12-10-2018 IPR005297 Lipoprotein repeat VAPA_1c40830 57350344bc1f76f3c390afd4e7c726f3 204 SMART SM00448 6 117 1.3E-28 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_1c40830 57350344bc1f76f3c390afd4e7c726f3 204 SMART SM00421 141 199 7.2E-11 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_1c40830 57350344bc1f76f3c390afd4e7c726f3 204 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 175 187 3.4E-6 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_1c40830 57350344bc1f76f3c390afd4e7c726f3 204 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 144 158 3.4E-6 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_1c40830 57350344bc1f76f3c390afd4e7c726f3 204 Pfam PF00196 Bacterial regulatory proteins, luxR family 143 195 2.7E-13 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_1c40830 57350344bc1f76f3c390afd4e7c726f3 204 Gene3D G3DSA:3.40.50.2300 3 133 1.2E-41 T 12-10-2018 VAPA_1c40830 57350344bc1f76f3c390afd4e7c726f3 204 SUPERFAMILY SSF46894 140 202 1.93E-13 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 VAPA_1c40830 57350344bc1f76f3c390afd4e7c726f3 204 Pfam PF00072 Response regulator receiver domain 9 117 3.5E-25 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_1c40830 57350344bc1f76f3c390afd4e7c726f3 204 SUPERFAMILY SSF52172 8 160 7.68E-33 T 12-10-2018 IPR011006 CheY-like superfamily VAPA_1c40830 57350344bc1f76f3c390afd4e7c726f3 204 Gene3D G3DSA:1.10.10.10 134 201 1.7E-18 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c32930 ff01be294e971f542d059f5a063248e7 365 SUPERFAMILY SSF53756 81 330 5.65E-28 T 12-10-2018 VAPA_1c32930 ff01be294e971f542d059f5a063248e7 365 Gene3D G3DSA:3.40.50.2000 17 180 3.8E-5 T 12-10-2018 VAPA_1c32930 ff01be294e971f542d059f5a063248e7 365 Pfam PF00534 Glycosyl transferases group 1 186 305 4.9E-7 T 12-10-2018 IPR001296 Glycosyl transferase, family 1 VAPA_1c32930 ff01be294e971f542d059f5a063248e7 365 Gene3D G3DSA:3.40.50.2000 182 336 9.4E-16 T 12-10-2018 VAPA_2c03100 40746b6c5c44c51fef9594563d2dce56 229 Gene3D G3DSA:3.50.30.100 4 198 2.7E-56 T 12-10-2018 VAPA_2c03100 40746b6c5c44c51fef9594563d2dce56 229 Pfam PF03737 Aldolase/RraA 31 176 1.2E-43 T 12-10-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein VAPA_2c03100 40746b6c5c44c51fef9594563d2dce56 229 SUPERFAMILY SSF89562 26 186 2.62E-47 T 12-10-2018 IPR036704 Ribonuclease E inhibitor RraA/RraA-like superfamily VAPA_1c35120 27740b91415307ee9a335161217f4267 110 Gene3D G3DSA:3.30.70.20 2 109 6.9E-36 T 12-10-2018 VAPA_1c35120 27740b91415307ee9a335161217f4267 110 Pfam PF00037 4Fe-4S binding domain 34 56 2.2E-9 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain VAPA_1c35120 27740b91415307ee9a335161217f4267 110 SUPERFAMILY SSF54862 3 77 1.7E-19 T 12-10-2018 VAPA_1c35120 27740b91415307ee9a335161217f4267 110 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 40 51 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site VAPA_1c35120 27740b91415307ee9a335161217f4267 110 PRINTS PR00354 7Fe ferredoxin signature 35 52 3.9E-14 T 12-10-2018 IPR000813 7Fe ferredoxin GO:0009055 VAPA_1c35120 27740b91415307ee9a335161217f4267 110 PRINTS PR00354 7Fe ferredoxin signature 9 19 3.9E-14 T 12-10-2018 IPR000813 7Fe ferredoxin GO:0009055 VAPA_1c35120 27740b91415307ee9a335161217f4267 110 PRINTS PR00354 7Fe ferredoxin signature 19 29 3.9E-14 T 12-10-2018 IPR000813 7Fe ferredoxin GO:0009055 VAPA_2c10220 f789740c11e5691e3918a0353790ca2a 325 Gene3D G3DSA:3.40.190.150 30 315 8.5E-98 T 12-10-2018 VAPA_2c10220 f789740c11e5691e3918a0353790ca2a 325 SUPERFAMILY SSF53850 115 285 9.15E-16 T 12-10-2018 VAPA_2c10220 f789740c11e5691e3918a0353790ca2a 325 Gene3D G3DSA:3.40.190.10 127 250 8.5E-98 T 12-10-2018 VAPA_2c10220 f789740c11e5691e3918a0353790ca2a 325 PIRSF PIRSF017082 1 325 2.4E-71 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_2c10220 f789740c11e5691e3918a0353790ca2a 325 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 50 321 6.0E-73 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c32170 223cd7bd3d85551a26b57aa3111d54a6 335 SUPERFAMILY SSF161098 144 327 2.62E-35 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c32170 223cd7bd3d85551a26b57aa3111d54a6 335 TIGRFAM TIGR01097 PhnE: phosphonate ABC transporter, permease protein PhnE 129 334 1.2E-78 T 12-10-2018 IPR005769 ABC transporter, permease PhnE/PtxC GO:0005887|GO:0015604|GO:0015716 VAPA_1c32170 223cd7bd3d85551a26b57aa3111d54a6 335 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 164 322 3.7E-14 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 VAPA_1c32170 223cd7bd3d85551a26b57aa3111d54a6 335 Gene3D G3DSA:1.10.3720.10 136 334 1.5E-33 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c39630 b377a413296a1173c712ca85e2483d7b 532 PIRSF PIRSF002741 2 532 4.7E-114 T 12-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 VAPA_1c39630 b377a413296a1173c712ca85e2483d7b 532 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 81 431 9.7E-73 T 12-10-2018 IPR000914 Solute-binding protein family 5 domain VAPA_1c39630 b377a413296a1173c712ca85e2483d7b 532 Gene3D G3DSA:3.10.105.10 284 502 1.3E-48 T 12-10-2018 VAPA_1c39630 b377a413296a1173c712ca85e2483d7b 532 SUPERFAMILY SSF53850 34 525 1.52E-117 T 12-10-2018 VAPA_1c39630 b377a413296a1173c712ca85e2483d7b 532 Gene3D G3DSA:3.40.190.10 11 281 9.2E-59 T 12-10-2018 VAPA_1c36360 e7d39d361437ce9d99f741aa9844cc23 566 SMART SM00331 21 232 8.7E-7 T 12-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 VAPA_1c36360 e7d39d361437ce9d99f741aa9844cc23 566 Pfam PF00069 Protein kinase domain 280 512 1.7E-28 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 VAPA_1c36360 e7d39d361437ce9d99f741aa9844cc23 566 Pfam PF13672 Protein phosphatase 2C 18 197 4.0E-9 T 12-10-2018 VAPA_1c36360 e7d39d361437ce9d99f741aa9844cc23 566 SMART SM00332 1 230 3.8E-7 T 12-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 VAPA_1c36360 e7d39d361437ce9d99f741aa9844cc23 566 Gene3D G3DSA:3.60.40.10 1 233 5.5E-39 T 12-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 VAPA_1c36360 e7d39d361437ce9d99f741aa9844cc23 566 SUPERFAMILY SSF56112 261 517 1.75E-47 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily VAPA_1c36360 e7d39d361437ce9d99f741aa9844cc23 566 Gene3D G3DSA:1.10.510.10 346 526 7.7E-37 T 12-10-2018 VAPA_1c36360 e7d39d361437ce9d99f741aa9844cc23 566 SMART SM00220 265 516 3.5E-12 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 VAPA_1c36360 e7d39d361437ce9d99f741aa9844cc23 566 Gene3D G3DSA:3.30.200.20 255 344 1.1E-9 T 12-10-2018 VAPA_1c36360 e7d39d361437ce9d99f741aa9844cc23 566 SUPERFAMILY SSF81606 5 232 6.93E-44 T 12-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 VAPA_1c13360 ce3eadf1c37a0c8b1ea9f55803530e12 345 PIRSF PIRSF004491 1 337 1.3E-79 T 12-10-2018 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 VAPA_1c13360 ce3eadf1c37a0c8b1ea9f55803530e12 345 Gene3D G3DSA:2.40.30.30 192 340 1.2E-20 T 12-10-2018 IPR023465 Riboflavin kinase domain superfamily GO:0008531|GO:0009231 Reactome: R-HSA-196843 VAPA_1c13360 ce3eadf1c37a0c8b1ea9f55803530e12 345 Pfam PF06574 FAD synthetase 15 170 5.1E-49 T 12-10-2018 IPR015864 FAD synthetase GO:0003919|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 VAPA_1c13360 ce3eadf1c37a0c8b1ea9f55803530e12 345 SMART SM00904 187 330 5.6E-41 T 12-10-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26|MetaCyc: PWY-5523|MetaCyc: PWY-6168|MetaCyc: PWY-7863|Reactome: R-HSA-196843 VAPA_1c13360 ce3eadf1c37a0c8b1ea9f55803530e12 345 SUPERFAMILY SSF52374 15 182 4.69E-33 T 12-10-2018 VAPA_1c13360 ce3eadf1c37a0c8b1ea9f55803530e12 345 SUPERFAMILY SSF82114 178 333 7.41E-28 T 12-10-2018 IPR023465 Riboflavin kinase domain superfamily GO:0008531|GO:0009231 Reactome: R-HSA-196843 VAPA_1c13360 ce3eadf1c37a0c8b1ea9f55803530e12 345 Gene3D G3DSA:3.40.50.620 7 190 1.7E-57 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold VAPA_1c13360 ce3eadf1c37a0c8b1ea9f55803530e12 345 TIGRFAM TIGR00083 ribF: riboflavin biosynthesis protein RibF 17 329 5.6E-72 T 12-10-2018 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 VAPA_1c13360 ce3eadf1c37a0c8b1ea9f55803530e12 345 Pfam PF01687 Riboflavin kinase 188 329 6.9E-25 T 12-10-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26|MetaCyc: PWY-5523|MetaCyc: PWY-6168|MetaCyc: PWY-7863|Reactome: R-HSA-196843 VAPA_2c04310 4adfb6edfbe06cbbbef8c3f06feb16ee 336 SUPERFAMILY SSF56112 12 306 1.69E-14 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily VAPA_1c20010 ca1dee14fb28009477e9adc8ac3677c6 249 SMART SM00382 45 232 4.1E-12 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c20010 ca1dee14fb28009477e9adc8ac3677c6 249 Pfam PF00005 ABC transporter 37 186 3.5E-33 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c20010 ca1dee14fb28009477e9adc8ac3677c6 249 ProSitePatterns PS00211 ABC transporters family signature. 158 172 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_1c20010 ca1dee14fb28009477e9adc8ac3677c6 249 SUPERFAMILY SSF52540 16 242 3.33E-67 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c20010 ca1dee14fb28009477e9adc8ac3677c6 249 Gene3D G3DSA:3.40.50.300 14 247 2.1E-70 T 12-10-2018 VAPA_1c44200 57d75362470cd3e4b7e6c5c7879d1676 148 Pfam PF00582 Universal stress protein family 1 148 6.2E-32 T 12-10-2018 IPR006016 UspA VAPA_1c44200 57d75362470cd3e4b7e6c5c7879d1676 148 PRINTS PR01438 Universal stress protein signature 108 120 2.2E-18 T 12-10-2018 IPR006015 Universal stress protein A VAPA_1c44200 57d75362470cd3e4b7e6c5c7879d1676 148 PRINTS PR01438 Universal stress protein signature 126 148 2.2E-18 T 12-10-2018 IPR006015 Universal stress protein A VAPA_1c44200 57d75362470cd3e4b7e6c5c7879d1676 148 PRINTS PR01438 Universal stress protein signature 2 20 2.2E-18 T 12-10-2018 IPR006015 Universal stress protein A VAPA_1c44200 57d75362470cd3e4b7e6c5c7879d1676 148 Gene3D G3DSA:3.40.50.620 1 148 3.6E-35 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold VAPA_1c44200 57d75362470cd3e4b7e6c5c7879d1676 148 SUPERFAMILY SSF52402 2 148 4.19E-34 T 12-10-2018 VAPA_1c03610 dfd493997342cf01ae7f63d93a6e0023 222 SUPERFAMILY SSF159594 37 220 2.17E-33 T 12-10-2018 VAPA_1c03610 dfd493997342cf01ae7f63d93a6e0023 222 Pfam PF03886 ABC-type transport auxiliary lipoprotein component 47 213 3.3E-17 T 12-10-2018 IPR005586 ABC-type transport auxiliary lipoprotein component VAPA_1c03610 dfd493997342cf01ae7f63d93a6e0023 222 Gene3D G3DSA:3.40.50.10610 32 222 1.0E-27 T 12-10-2018 VAPA_1c49740 3ab15fba62bede8031e540c22b1737fb 423 SUPERFAMILY SSF51735 189 422 2.66E-72 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c49740 3ab15fba62bede8031e540c22b1737fb 423 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 43 171 1.3E-54 T 12-10-2018 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 VAPA_1c49740 3ab15fba62bede8031e540c22b1737fb 423 Gene3D G3DSA:1.10.8.1210 1 49 2.8E-19 T 12-10-2018 VAPA_1c49740 3ab15fba62bede8031e540c22b1737fb 423 Gene3D G3DSA:3.40.50.720 189 423 3.7E-83 T 12-10-2018 VAPA_1c49740 3ab15fba62bede8031e540c22b1737fb 423 ProSitePatterns PS00074 Glu / Leu / Phe / Val dehydrogenases active site. 108 121 - T 12-10-2018 IPR033524 Leu/Phe/Val dehydrogenases active site Reactome: R-HSA-2151201|Reactome: R-HSA-70614 VAPA_1c49740 3ab15fba62bede8031e540c22b1737fb 423 Gene3D G3DSA:3.40.50.10860 50 188 2.4E-64 T 12-10-2018 VAPA_1c49740 3ab15fba62bede8031e540c22b1737fb 423 PIRSF PIRSF000185 11 423 7.1E-157 T 12-10-2018 IPR014362 Glutamate dehydrogenase GO:0016639|GO:0055114 VAPA_1c49740 3ab15fba62bede8031e540c22b1737fb 423 SMART SM00839 191 420 1.7E-91 T 12-10-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 VAPA_1c49740 3ab15fba62bede8031e540c22b1737fb 423 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 348 359 7.4E-33 T 12-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 VAPA_1c49740 3ab15fba62bede8031e540c22b1737fb 423 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 100 114 7.4E-33 T 12-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 VAPA_1c49740 3ab15fba62bede8031e540c22b1737fb 423 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 222 242 7.4E-33 T 12-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 VAPA_1c49740 3ab15fba62bede8031e540c22b1737fb 423 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 180 202 7.4E-33 T 12-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 VAPA_1c49740 3ab15fba62bede8031e540c22b1737fb 423 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 189 420 1.2E-71 T 12-10-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 VAPA_1c49740 3ab15fba62bede8031e540c22b1737fb 423 SUPERFAMILY SSF53223 4 191 3.04E-69 T 12-10-2018 VAPA_2c05990 0d803d2b6e56850115a8dfa4cedc3835 599 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 115 410 7.1E-21 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 VAPA_2c05990 0d803d2b6e56850115a8dfa4cedc3835 599 Gene3D G3DSA:1.10.1060.10 7 112 5.7E-20 T 12-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 VAPA_2c05990 0d803d2b6e56850115a8dfa4cedc3835 599 SUPERFAMILY SSF51971 330 422 2.59E-6 T 12-10-2018 VAPA_2c05990 0d803d2b6e56850115a8dfa4cedc3835 599 PRINTS PR00419 Adrenodoxin reductase family signature 115 137 3.8E-15 T 12-10-2018 VAPA_2c05990 0d803d2b6e56850115a8dfa4cedc3835 599 PRINTS PR00419 Adrenodoxin reductase family signature 246 260 3.8E-15 T 12-10-2018 VAPA_2c05990 0d803d2b6e56850115a8dfa4cedc3835 599 PRINTS PR00419 Adrenodoxin reductase family signature 138 151 3.8E-15 T 12-10-2018 VAPA_2c05990 0d803d2b6e56850115a8dfa4cedc3835 599 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 17 99 8.0E-14 T 12-10-2018 IPR028261 Dihydroprymidine dehydrogenase domain II Reactome: R-HSA-73621 VAPA_2c05990 0d803d2b6e56850115a8dfa4cedc3835 599 Pfam PF12838 4Fe-4S dicluster domain 505 580 1.6E-11 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain VAPA_2c05990 0d803d2b6e56850115a8dfa4cedc3835 599 SUPERFAMILY SSF54862 18 586 8.37E-18 T 12-10-2018 VAPA_2c05990 0d803d2b6e56850115a8dfa4cedc3835 599 SUPERFAMILY SSF51971 113 355 1.18E-43 T 12-10-2018 VAPA_2c05990 0d803d2b6e56850115a8dfa4cedc3835 599 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 566 577 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site VAPA_2c05990 0d803d2b6e56850115a8dfa4cedc3835 599 Gene3D G3DSA:3.50.50.60 241 441 7.0E-25 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_2c05990 0d803d2b6e56850115a8dfa4cedc3835 599 Gene3D G3DSA:3.50.50.60 113 228 8.9E-29 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c10220 40836cfc4764c1352b524079940827ee 454 Pfam PF01938 TRAM domain 378 438 3.8E-13 T 12-10-2018 IPR002792 TRAM domain VAPA_1c10220 40836cfc4764c1352b524079940827ee 454 Pfam PF04055 Radical SAM superfamily 149 324 1.0E-28 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 VAPA_1c10220 40836cfc4764c1352b524079940827ee 454 Gene3D G3DSA:3.40.50.12160 3 135 1.8E-34 T 12-10-2018 IPR038135 Methylthiotransferase, N-terminal domain superfamily VAPA_1c10220 40836cfc4764c1352b524079940827ee 454 SUPERFAMILY SSF102114 125 370 1.96E-56 T 12-10-2018 VAPA_1c10220 40836cfc4764c1352b524079940827ee 454 Gene3D G3DSA:3.80.30.20 143 374 2.7E-80 T 12-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe VAPA_1c10220 40836cfc4764c1352b524079940827ee 454 SMART SM00729 145 366 2.7E-57 T 12-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 VAPA_1c10220 40836cfc4764c1352b524079940827ee 454 Hamap MF_01864 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase [miaB]. 3 439 71.723 T 12-10-2018 IPR006463 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase MiaB GO:0005737|GO:0006400|GO:0016740|GO:0051539 VAPA_1c10220 40836cfc4764c1352b524079940827ee 454 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 4 436 1.5E-144 T 12-10-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 VAPA_1c10220 40836cfc4764c1352b524079940827ee 454 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 149 169 - T 12-10-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 VAPA_1c10220 40836cfc4764c1352b524079940827ee 454 Pfam PF00919 Uncharacterized protein family UPF0004 4 102 9.5E-31 T 12-10-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 VAPA_1c10220 40836cfc4764c1352b524079940827ee 454 TIGRFAM TIGR01574 miaB-methiolase: tRNA-i(6)A37 thiotransferase enzyme MiaB 4 438 4.5E-172 T 12-10-2018 VAPA_1c22110 c4c58d55d6f1bae9f802b7064f520222 339 Gene3D G3DSA:1.10.10.60 230 336 2.0E-23 T 12-10-2018 VAPA_1c22110 c4c58d55d6f1bae9f802b7064f520222 339 Pfam PF12833 Helix-turn-helix domain 256 333 2.2E-18 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 VAPA_1c22110 c4c58d55d6f1bae9f802b7064f520222 339 SUPERFAMILY SSF46689 285 334 1.7E-12 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 VAPA_1c22110 c4c58d55d6f1bae9f802b7064f520222 339 Pfam PF12625 Arabinose-binding domain of AraC transcription regulator, N-term 27 205 3.5E-37 T 12-10-2018 IPR032687 HTH-type transcriptional regulator AraC-type, N-terminal VAPA_1c22110 c4c58d55d6f1bae9f802b7064f520222 339 SMART SM00342 249 332 4.8E-22 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 VAPA_1c22110 c4c58d55d6f1bae9f802b7064f520222 339 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 301 316 2.6E-6 T 12-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 VAPA_1c22110 c4c58d55d6f1bae9f802b7064f520222 339 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 316 332 2.6E-6 T 12-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 VAPA_1c35340 cb4571416b583a9ca949396804edb28b 296 ProSitePatterns PS00922 Prokaryotic transglycosylases signature. 114 142 - T 12-10-2018 IPR000189 Prokaryotic transglycosylase, active site GO:0000270|GO:0008933|GO:0016020 VAPA_1c35340 cb4571416b583a9ca949396804edb28b 296 Gene3D G3DSA:1.10.530.10 94 234 4.3E-43 T 12-10-2018 VAPA_1c35340 cb4571416b583a9ca949396804edb28b 296 Pfam PF01464 Transglycosylase SLT domain 99 205 1.0E-29 T 12-10-2018 IPR008258 Transglycosylase SLT domain 1 VAPA_1c35340 cb4571416b583a9ca949396804edb28b 296 SUPERFAMILY SSF53955 95 226 4.79E-43 T 12-10-2018 IPR023346 Lysozyme-like domain superfamily VAPA_2c03050 596fa31c5e833f4eaf8075261b90f5ac 308 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 266 284 7.4E-11 T 12-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) VAPA_2c03050 596fa31c5e833f4eaf8075261b90f5ac 308 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 223 240 7.4E-11 T 12-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) VAPA_2c03050 596fa31c5e833f4eaf8075261b90f5ac 308 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 162 184 7.4E-11 T 12-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) VAPA_2c03050 596fa31c5e833f4eaf8075261b90f5ac 308 Gene3D G3DSA:2.120.10.30 38 304 1.9E-70 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like VAPA_2c03050 596fa31c5e833f4eaf8075261b90f5ac 308 SUPERFAMILY SSF63829 41 301 8.28E-66 T 12-10-2018 VAPA_2c03050 596fa31c5e833f4eaf8075261b90f5ac 308 Pfam PF08450 SMP-30/Gluconolaconase/LRE-like region 45 283 1.9E-45 T 12-10-2018 IPR013658 SMP-30/Gluconolactonase/LRE-like region VAPA_2c11250 699611d39d4e5fb53199a83c6f2fc6ee 327 PIRSF PIRSF017082 1 327 1.6E-74 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_2c11250 699611d39d4e5fb53199a83c6f2fc6ee 327 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 52 323 6.8E-83 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_2c11250 699611d39d4e5fb53199a83c6f2fc6ee 327 SUPERFAMILY SSF53850 117 290 2.09E-12 T 12-10-2018 VAPA_2c11250 699611d39d4e5fb53199a83c6f2fc6ee 327 Gene3D G3DSA:3.40.190.150 33 317 1.3E-102 T 12-10-2018 VAPA_2c11250 699611d39d4e5fb53199a83c6f2fc6ee 327 Gene3D G3DSA:3.40.190.10 129 252 1.3E-102 T 12-10-2018 VAPA_1c04530 c711e099703cc1c84a25cc308a5875c1 587 Gene3D G3DSA:1.10.8.870 438 565 6.2E-15 T 12-10-2018 IPR038299 Alpha-glycerophosphate oxidase, C-terminal domain superfamily KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 VAPA_1c04530 c711e099703cc1c84a25cc308a5875c1 587 Pfam PF01266 FAD dependent oxidoreductase 21 364 3.9E-38 T 12-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 VAPA_1c04530 c711e099703cc1c84a25cc308a5875c1 587 Pfam PF16901 C-terminal domain of alpha-glycerophosphate oxidase 419 541 9.5E-15 T 12-10-2018 IPR031656 Alpha-glycerophosphate oxidase, C-terminal KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 VAPA_1c04530 c711e099703cc1c84a25cc308a5875c1 587 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 48 60 7.7E-16 T 12-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 VAPA_1c04530 c711e099703cc1c84a25cc308a5875c1 587 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 19 31 7.7E-16 T 12-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 VAPA_1c04530 c711e099703cc1c84a25cc308a5875c1 587 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 93 105 7.7E-16 T 12-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 VAPA_1c04530 c711e099703cc1c84a25cc308a5875c1 587 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 386 398 7.7E-16 T 12-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 VAPA_1c04530 c711e099703cc1c84a25cc308a5875c1 587 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 350 356 7.7E-16 T 12-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 VAPA_1c04530 c711e099703cc1c84a25cc308a5875c1 587 SUPERFAMILY SSF54373 260 356 1.44E-7 T 12-10-2018 VAPA_1c04530 c711e099703cc1c84a25cc308a5875c1 587 Gene3D G3DSA:3.50.50.60 22 405 1.6E-94 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c04530 c711e099703cc1c84a25cc308a5875c1 587 Gene3D G3DSA:3.30.9.10 97 357 1.6E-94 T 12-10-2018 VAPA_1c04530 c711e099703cc1c84a25cc308a5875c1 587 SUPERFAMILY SSF51905 17 262 1.86E-15 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c51280 97e9853a3bc5361192fb31e51f348263 430 Pfam PF00144 Beta-lactamase 119 405 2.8E-33 T 12-10-2018 IPR001466 Beta-lactamase-related VAPA_1c51280 97e9853a3bc5361192fb31e51f348263 430 Gene3D G3DSA:3.40.710.10 113 405 6.9E-112 T 12-10-2018 VAPA_1c51280 97e9853a3bc5361192fb31e51f348263 430 Gene3D G3DSA:1.20.58.710 164 271 6.9E-112 T 12-10-2018 VAPA_1c51280 97e9853a3bc5361192fb31e51f348263 430 SUPERFAMILY SSF56601 49 428 2.2E-89 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like VAPA_1c37180 b4cc2fb759e54bc80b32149cfaad829f 222 Pfam PF00196 Bacterial regulatory proteins, luxR family 160 215 9.1E-8 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_1c37180 b4cc2fb759e54bc80b32149cfaad829f 222 SUPERFAMILY SSF52172 13 129 1.57E-23 T 12-10-2018 IPR011006 CheY-like superfamily VAPA_1c37180 b4cc2fb759e54bc80b32149cfaad829f 222 Pfam PF00072 Response regulator receiver domain 13 118 6.7E-19 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_1c37180 b4cc2fb759e54bc80b32149cfaad829f 222 Gene3D G3DSA:1.10.10.10 113 222 1.9E-18 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c37180 b4cc2fb759e54bc80b32149cfaad829f 222 SMART SM00421 158 215 9.9E-6 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_1c37180 b4cc2fb759e54bc80b32149cfaad829f 222 Gene3D G3DSA:3.40.50.2300 10 112 6.1E-18 T 12-10-2018 VAPA_1c37180 b4cc2fb759e54bc80b32149cfaad829f 222 SMART SM00448 10 124 9.5E-20 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_1c37180 b4cc2fb759e54bc80b32149cfaad829f 222 SUPERFAMILY SSF46894 158 220 9.86E-11 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 VAPA_1c13760 0ca86c8961ffcc6e53f28e71715f213c 299 SUPERFAMILY SSF53474 5 290 7.01E-60 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c13760 0ca86c8961ffcc6e53f28e71715f213c 299 Gene3D G3DSA:3.40.50.1820 3 293 5.9E-65 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c13760 0ca86c8961ffcc6e53f28e71715f213c 299 Pfam PF12146 Serine aminopeptidase, S33 34 275 2.5E-16 T 12-10-2018 IPR022742 Serine aminopeptidase, S33 VAPA_1c01860 286ea752a93a7286c5d262ffc896bb23 633 TIGRFAM TIGR01389 recQ: ATP-dependent DNA helicase RecQ 20 631 2.0E-233 T 12-10-2018 IPR006293 DNA helicase, ATP-dependent, RecQ type, bacterial GO:0004003|GO:0006310|GO:0009432 VAPA_1c01860 286ea752a93a7286c5d262ffc896bb23 633 Pfam PF16124 RecQ zinc-binding 357 418 8.6E-18 T 12-10-2018 IPR032284 ATP-dependent DNA helicase RecQ, zinc-binding domain VAPA_1c01860 286ea752a93a7286c5d262ffc896bb23 633 SUPERFAMILY SSF52540 13 216 6.74E-38 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c01860 286ea752a93a7286c5d262ffc896bb23 633 Pfam PF00270 DEAD/DEAH box helicase 35 198 1.7E-16 T 12-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 VAPA_1c01860 286ea752a93a7286c5d262ffc896bb23 633 TIGRFAM TIGR00614 recQ_fam: ATP-dependent DNA helicase, RecQ family 20 480 4.7E-154 T 12-10-2018 IPR004589 DNA helicase, ATP-dependent, RecQ type GO:0006310|GO:0008026 VAPA_1c01860 286ea752a93a7286c5d262ffc896bb23 633 SMART SM00341 560 633 7.1E-8 T 12-10-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 VAPA_1c01860 286ea752a93a7286c5d262ffc896bb23 633 Pfam PF09382 RQC domain 420 535 1.9E-36 T 12-10-2018 IPR018982 RQC domain GO:0006260|GO:0006281|GO:0043140 Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 VAPA_1c01860 286ea752a93a7286c5d262ffc896bb23 633 SUPERFAMILY SSF52540 221 476 1.42E-60 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c01860 286ea752a93a7286c5d262ffc896bb23 633 Gene3D G3DSA:1.10.150.80 562 632 9.3E-22 T 12-10-2018 VAPA_1c01860 286ea752a93a7286c5d262ffc896bb23 633 SMART SM00490 264 345 5.1E-25 T 12-10-2018 IPR001650 Helicase, C-terminal VAPA_1c01860 286ea752a93a7286c5d262ffc896bb23 633 SUPERFAMILY SSF47819 559 632 7.2E-21 T 12-10-2018 IPR010997 HRDC-like superfamily GO:0000166|GO:0003824|GO:0044237 VAPA_1c01860 286ea752a93a7286c5d262ffc896bb23 633 Pfam PF00271 Helicase conserved C-terminal domain 238 344 1.7E-17 T 12-10-2018 IPR001650 Helicase, C-terminal VAPA_1c01860 286ea752a93a7286c5d262ffc896bb23 633 SMART SM00956 425 532 3.1E-49 T 12-10-2018 IPR018982 RQC domain GO:0006260|GO:0006281|GO:0043140 Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 VAPA_1c01860 286ea752a93a7286c5d262ffc896bb23 633 Gene3D G3DSA:1.10.10.10 355 540 4.8E-47 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c01860 286ea752a93a7286c5d262ffc896bb23 633 SMART SM00487 27 231 5.3E-26 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain VAPA_1c01860 286ea752a93a7286c5d262ffc896bb23 633 Gene3D G3DSA:3.40.50.300 223 354 5.5E-40 T 12-10-2018 VAPA_1c01860 286ea752a93a7286c5d262ffc896bb23 633 Gene3D G3DSA:3.40.50.300 10 222 1.0E-75 T 12-10-2018 VAPA_1c01860 286ea752a93a7286c5d262ffc896bb23 633 Pfam PF00570 HRDC domain 565 629 7.0E-22 T 12-10-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 VAPA_2c04980 6027d94193e8989e95ba8670d902b26d 1102 Gene3D G3DSA:3.30.70.1430 595 705 3.9E-220 T 12-10-2018 VAPA_2c04980 6027d94193e8989e95ba8670d902b26d 1102 Gene3D G3DSA:3.30.70.1430 52 851 3.9E-220 T 12-10-2018 VAPA_2c04980 6027d94193e8989e95ba8670d902b26d 1102 Gene3D G3DSA:3.30.70.1440 706 920 3.9E-220 T 12-10-2018 VAPA_2c04980 6027d94193e8989e95ba8670d902b26d 1102 Gene3D G3DSA:3.30.70.1320 148 349 3.9E-220 T 12-10-2018 VAPA_2c04980 6027d94193e8989e95ba8670d902b26d 1102 SUPERFAMILY SSF82866 847 1076 1.31E-40 T 12-10-2018 VAPA_2c04980 6027d94193e8989e95ba8670d902b26d 1102 Pfam PF00873 AcrB/AcrD/AcrF family 25 1071 3.0E-139 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 VAPA_2c04980 6027d94193e8989e95ba8670d902b26d 1102 SUPERFAMILY SSF82866 314 517 2.22E-35 T 12-10-2018 VAPA_2c04980 6027d94193e8989e95ba8670d902b26d 1102 Gene3D G3DSA:3.30.2090.10 754 843 3.9E-220 T 12-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains VAPA_2c04980 6027d94193e8989e95ba8670d902b26d 1102 Gene3D G3DSA:1.20.1640.10 536 1070 3.9E-220 T 12-10-2018 VAPA_2c04980 6027d94193e8989e95ba8670d902b26d 1102 SUPERFAMILY SSF82714 755 839 4.84E-9 T 12-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains VAPA_2c04980 6027d94193e8989e95ba8670d902b26d 1102 SUPERFAMILY SSF82693 52 144 8.2E-19 T 12-10-2018 VAPA_2c04980 6027d94193e8989e95ba8670d902b26d 1102 Gene3D G3DSA:1.20.1640.10 28 535 3.9E-220 T 12-10-2018 VAPA_2c04980 6027d94193e8989e95ba8670d902b26d 1102 SUPERFAMILY SSF82693 155 343 4.92E-6 T 12-10-2018 VAPA_2c04980 6027d94193e8989e95ba8670d902b26d 1102 Gene3D G3DSA:3.30.2090.10 194 285 3.9E-220 T 12-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains VAPA_2c04980 6027d94193e8989e95ba8670d902b26d 1102 SUPERFAMILY SSF82714 198 279 5.36E-14 T 12-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains VAPA_2c04980 6027d94193e8989e95ba8670d902b26d 1102 PRINTS PR00702 Acriflavin resistance protein family signature 409 433 1.3E-26 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 VAPA_2c04980 6027d94193e8989e95ba8670d902b26d 1102 PRINTS PR00702 Acriflavin resistance protein family signature 355 378 1.3E-26 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 VAPA_2c04980 6027d94193e8989e95ba8670d902b26d 1102 PRINTS PR00702 Acriflavin resistance protein family signature 489 512 1.3E-26 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 VAPA_2c04980 6027d94193e8989e95ba8670d902b26d 1102 PRINTS PR00702 Acriflavin resistance protein family signature 464 487 1.3E-26 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 VAPA_2c04980 6027d94193e8989e95ba8670d902b26d 1102 PRINTS PR00702 Acriflavin resistance protein family signature 22 46 1.3E-26 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 VAPA_2c04980 6027d94193e8989e95ba8670d902b26d 1102 PRINTS PR00702 Acriflavin resistance protein family signature 50 68 1.3E-26 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 VAPA_2c04980 6027d94193e8989e95ba8670d902b26d 1102 SUPERFAMILY SSF82693 591 705 3.35E-13 T 12-10-2018 VAPA_1c47580 9a3b4e5c73e0d06d3476edb849de52a1 199 SUPERFAMILY SSF143456 8 199 1.7E-61 T 12-10-2018 VAPA_1c47580 9a3b4e5c73e0d06d3476edb849de52a1 199 Gene3D G3DSA:3.40.1740.10 3 199 1.1E-66 T 12-10-2018 VAPA_1c47580 9a3b4e5c73e0d06d3476edb849de52a1 199 Hamap MF_00758 UPF0301 protein YqgE [yqgE]. 8 199 37.555 T 12-10-2018 IPR003774 Protein of unknown function UPF0301 VAPA_1c47580 9a3b4e5c73e0d06d3476edb849de52a1 199 Pfam PF02622 Uncharacterized ACR, COG1678 19 186 1.8E-49 T 12-10-2018 IPR003774 Protein of unknown function UPF0301 VAPA_1c07420 783e1d2b56ba883427cadc08dc0cfad5 1374 Gene3D G3DSA:3.90.1800.10 1284 1338 4.4E-11 T 12-10-2018 VAPA_1c07420 783e1d2b56ba883427cadc08dc0cfad5 1374 Pfam PF00562 RNA polymerase Rpb2, domain 6 730 1296 4.0E-157 T 12-10-2018 IPR007120 DNA-directed RNA polymerase, subunit 2, hybrid-binding domain GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 VAPA_1c07420 783e1d2b56ba883427cadc08dc0cfad5 1374 Gene3D G3DSA:2.40.50.150 845 965 4.3E-43 T 12-10-2018 IPR014724 RNA polymerase Rpb2, OB-fold GO:0003899 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 VAPA_1c07420 783e1d2b56ba883427cadc08dc0cfad5 1374 Gene3D G3DSA:3.90.1100.10 454 654 5.8E-70 T 12-10-2018 VAPA_1c07420 783e1d2b56ba883427cadc08dc0cfad5 1374 ProSitePatterns PS01166 RNA polymerases beta chain signature. 1088 1100 - T 12-10-2018 IPR007121 RNA polymerase, beta subunit, conserved site GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 VAPA_1c07420 783e1d2b56ba883427cadc08dc0cfad5 1374 Gene3D G3DSA:2.40.270.10 802 844 6.5E-7 T 12-10-2018 IPR037033 DNA-directed RNA polymerase, subunit 2, hybrid-binding domain superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 VAPA_1c07420 783e1d2b56ba883427cadc08dc0cfad5 1374 Pfam PF04563 RNA polymerase beta subunit 30 512 4.3E-32 T 12-10-2018 IPR007644 RNA polymerase, beta subunit, protrusion GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 VAPA_1c07420 783e1d2b56ba883427cadc08dc0cfad5 1374 Gene3D G3DSA:2.40.270.10 1060 1274 4.7E-80 T 12-10-2018 IPR037033 DNA-directed RNA polymerase, subunit 2, hybrid-binding domain superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 VAPA_1c07420 783e1d2b56ba883427cadc08dc0cfad5 1374 Hamap MF_01321 DNA-directed RNA polymerase subunit beta [rpoB]. 17 1374 12.226 T 12-10-2018 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 VAPA_1c07420 783e1d2b56ba883427cadc08dc0cfad5 1374 Pfam PF04561 RNA polymerase Rpb2, domain 2 162 234 6.8E-6 T 12-10-2018 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 VAPA_1c07420 783e1d2b56ba883427cadc08dc0cfad5 1374 Pfam PF04561 RNA polymerase Rpb2, domain 2 374 466 2.3E-15 T 12-10-2018 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 VAPA_1c07420 783e1d2b56ba883427cadc08dc0cfad5 1374 Gene3D G3DSA:3.90.1110.10 320 453 3.1E-32 T 12-10-2018 IPR037034 RNA polymerase Rpb2, domain 2 superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 VAPA_1c07420 783e1d2b56ba883427cadc08dc0cfad5 1374 Gene3D G3DSA:2.40.50.100 726 800 3.3E-29 T 12-10-2018 VAPA_1c07420 783e1d2b56ba883427cadc08dc0cfad5 1374 SUPERFAMILY SSF64484 16 1372 0.0 T 12-10-2018 VAPA_1c07420 783e1d2b56ba883427cadc08dc0cfad5 1374 Pfam PF04560 RNA polymerase Rpb2, domain 7 1298 1372 7.0E-27 T 12-10-2018 IPR007641 RNA polymerase Rpb2, domain 7 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 VAPA_1c07420 783e1d2b56ba883427cadc08dc0cfad5 1374 Pfam PF10385 RNA polymerase beta subunit external 1 domain 603 668 9.0E-24 T 12-10-2018 IPR019462 DNA-directed RNA polymerase, beta subunit, external 1 domain GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 VAPA_1c07420 783e1d2b56ba883427cadc08dc0cfad5 1374 TIGRFAM TIGR02013 rpoB: DNA-directed RNA polymerase, beta subunit 13 1371 0.0 T 12-10-2018 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 VAPA_1c07420 783e1d2b56ba883427cadc08dc0cfad5 1374 Pfam PF04565 RNA polymerase Rpb2, domain 3 525 592 6.2E-31 T 12-10-2018 IPR007645 RNA polymerase Rpb2, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 VAPA_1c07420 783e1d2b56ba883427cadc08dc0cfad5 1374 Gene3D G3DSA:3.90.1100.10 22 182 5.7E-49 T 12-10-2018 VAPA_1c07420 783e1d2b56ba883427cadc08dc0cfad5 1374 Gene3D G3DSA:3.90.1100.10 655 725 6.0E-21 T 12-10-2018 VAPA_1c23570 6475a7d7cea3defbfea4db9f3853e927 81 Pfam PF04325 Protein of unknown function (DUF465) 28 72 1.7E-13 T 12-10-2018 IPR007420 Protein of unknown function DUF465 VAPA_1c23570 6475a7d7cea3defbfea4db9f3853e927 81 Gene3D G3DSA:1.20.58.660 17 78 8.8E-6 T 12-10-2018 VAPA_1c45390 a123d6003a5fed2ce96c4fd013e0d1f3 332 SUPERFAMILY SSF50891 190 303 2.65E-13 T 12-10-2018 IPR029000 Cyclophilin-like domain superfamily VAPA_1c45390 a123d6003a5fed2ce96c4fd013e0d1f3 332 SMART SM00797 23 315 2.7E-127 T 12-10-2018 IPR003778 Carboxyltransferase domain, subdomain A and B VAPA_1c45390 a123d6003a5fed2ce96c4fd013e0d1f3 332 Pfam PF02626 Carboxyltransferase domain, subdomain A and B 24 297 5.2E-88 T 12-10-2018 IPR003778 Carboxyltransferase domain, subdomain A and B VAPA_1c45390 a123d6003a5fed2ce96c4fd013e0d1f3 332 Gene3D G3DSA:2.40.100.10 188 326 6.2E-51 T 12-10-2018 IPR029000 Cyclophilin-like domain superfamily VAPA_1c45390 a123d6003a5fed2ce96c4fd013e0d1f3 332 TIGRFAM TIGR00724 urea_amlyse_rel: biotin-dependent carboxylase uncharacterized domain 4 322 2.4E-93 T 12-10-2018 IPR003778 Carboxyltransferase domain, subdomain A and B VAPA_1c22280 9e3bf75f8633d766fe5ab480e04fbf51 147 TIGRFAM TIGR00673 cynS: cyanase 6 147 7.2E-52 T 12-10-2018 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00910+4.2.1.104 VAPA_1c22280 9e3bf75f8633d766fe5ab480e04fbf51 147 SMART SM01116 75 147 1.2E-51 T 12-10-2018 IPR003712 Cyanate lyase, C-terminal GO:0009439 KEGG: 00910+4.2.1.104 VAPA_1c22280 9e3bf75f8633d766fe5ab480e04fbf51 147 PRINTS PR01693 Cyanase signature 101 117 8.0E-29 T 12-10-2018 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00910+4.2.1.104 VAPA_1c22280 9e3bf75f8633d766fe5ab480e04fbf51 147 PRINTS PR01693 Cyanase signature 83 97 8.0E-29 T 12-10-2018 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00910+4.2.1.104 VAPA_1c22280 9e3bf75f8633d766fe5ab480e04fbf51 147 PRINTS PR01693 Cyanase signature 34 51 8.0E-29 T 12-10-2018 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00910+4.2.1.104 VAPA_1c22280 9e3bf75f8633d766fe5ab480e04fbf51 147 PRINTS PR01693 Cyanase signature 14 29 8.0E-29 T 12-10-2018 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00910+4.2.1.104 VAPA_1c22280 9e3bf75f8633d766fe5ab480e04fbf51 147 PRINTS PR01693 Cyanase signature 132 142 8.0E-29 T 12-10-2018 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00910+4.2.1.104 VAPA_1c22280 9e3bf75f8633d766fe5ab480e04fbf51 147 SUPERFAMILY SSF47413 1 77 6.33E-21 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 VAPA_1c22280 9e3bf75f8633d766fe5ab480e04fbf51 147 Hamap MF_00535 Cyanate hydratase [cynS]. 1 147 82.767 T 12-10-2018 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00910+4.2.1.104 VAPA_1c22280 9e3bf75f8633d766fe5ab480e04fbf51 147 Gene3D G3DSA:3.30.1160.10 81 147 4.8E-35 T 12-10-2018 IPR036581 Cyanate lyase, C-terminal domain superfamily GO:0009439 KEGG: 00910+4.2.1.104 VAPA_1c22280 9e3bf75f8633d766fe5ab480e04fbf51 147 Pfam PF02560 Cyanate lyase C-terminal domain 79 145 4.6E-36 T 12-10-2018 IPR003712 Cyanate lyase, C-terminal GO:0009439 KEGG: 00910+4.2.1.104 VAPA_1c22280 9e3bf75f8633d766fe5ab480e04fbf51 147 SUPERFAMILY SSF55234 80 147 2.09E-30 T 12-10-2018 IPR036581 Cyanate lyase, C-terminal domain superfamily GO:0009439 KEGG: 00910+4.2.1.104 VAPA_1c22280 9e3bf75f8633d766fe5ab480e04fbf51 147 Gene3D G3DSA:1.10.260.40 1 80 2.8E-30 T 12-10-2018 VAPA_1c22280 9e3bf75f8633d766fe5ab480e04fbf51 147 PIRSF PIRSF001263 1 147 9.3E-52 T 12-10-2018 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00910+4.2.1.104 VAPA_2c03280 95ae99491c0988c3136bdbe3a07e930e 450 SMART SM01027 247 366 3.4E-51 T 12-10-2018 IPR022712 Beta-Casp domain VAPA_2c03280 95ae99491c0988c3136bdbe3a07e930e 450 Gene3D G3DSA:3.60.15.10 6 426 4.9E-134 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like VAPA_2c03280 95ae99491c0988c3136bdbe3a07e930e 450 SUPERFAMILY SSF56281 1 447 2.36E-126 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like VAPA_2c03280 95ae99491c0988c3136bdbe3a07e930e 450 Pfam PF10996 Beta-Casp domain 247 366 6.6E-25 T 12-10-2018 IPR022712 Beta-Casp domain VAPA_2c03280 95ae99491c0988c3136bdbe3a07e930e 450 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 379 442 2.1E-14 T 12-10-2018 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain VAPA_2c03280 95ae99491c0988c3136bdbe3a07e930e 450 SMART SM00849 13 235 1.1E-15 T 12-10-2018 IPR001279 Metallo-beta-lactamase VAPA_2c03280 95ae99491c0988c3136bdbe3a07e930e 450 Pfam PF00753 Metallo-beta-lactamase superfamily 16 194 5.0E-17 T 12-10-2018 IPR001279 Metallo-beta-lactamase VAPA_2c03280 95ae99491c0988c3136bdbe3a07e930e 450 Gene3D G3DSA:3.40.50.10890 217 392 4.9E-134 T 12-10-2018 VAPA_1c15210 48532e87ad549b023a06debc16732399 602 PIRSF PIRSF000171 3 583 1.2E-40 T 12-10-2018 VAPA_1c15210 48532e87ad549b023a06debc16732399 602 Gene3D G3DSA:3.50.50.60 14 420 5.4E-164 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c15210 48532e87ad549b023a06debc16732399 602 Pfam PF02910 Fumarate reductase flavoprotein C-term 466 601 5.4E-38 T 12-10-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 VAPA_1c15210 48532e87ad549b023a06debc16732399 602 SUPERFAMILY SSF56425 241 359 3.14E-42 T 12-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 VAPA_1c15210 48532e87ad549b023a06debc16732399 602 Gene3D G3DSA:3.90.700.10 251 354 5.4E-164 T 12-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 VAPA_1c15210 48532e87ad549b023a06debc16732399 602 TIGRFAM TIGR01812 sdhA_frdA_Gneg: succinate dehydrogenase or fumarate reductase, flavoprotein subunit 14 601 9.6E-235 T 12-10-2018 IPR014006 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit GO:0016627|GO:0022900|GO:0050660|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 VAPA_1c15210 48532e87ad549b023a06debc16732399 602 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 387 394 4.0E-6 T 12-10-2018 VAPA_1c15210 48532e87ad549b023a06debc16732399 602 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 14 36 4.0E-6 T 12-10-2018 VAPA_1c15210 48532e87ad549b023a06debc16732399 602 SUPERFAMILY SSF51905 9 439 6.26E-80 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c15210 48532e87ad549b023a06debc16732399 602 ProSitePatterns PS00504 Fumarate reductase / succinate dehydrogenase FAD-binding site. 48 57 - T 12-10-2018 IPR003952 Fumarate reductase/succinate dehydrogenase, FAD-binding site GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 VAPA_1c15210 48532e87ad549b023a06debc16732399 602 Gene3D G3DSA:1.20.58.100 437 551 2.5E-32 T 12-10-2018 VAPA_1c15210 48532e87ad549b023a06debc16732399 602 TIGRFAM TIGR01816 sdhA_forward: succinate dehydrogenase, flavoprotein subunit 11 602 3.0E-279 T 12-10-2018 IPR011281 Succinate dehydrogenase, flavoprotein subunit GO:0006099|GO:0016627|GO:0050660|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 VAPA_1c15210 48532e87ad549b023a06debc16732399 602 SUPERFAMILY SSF46977 456 602 9.29E-40 T 12-10-2018 IPR037099 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain superfamily GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 VAPA_1c15210 48532e87ad549b023a06debc16732399 602 Gene3D G3DSA:4.10.80.40 562 602 1.5E-11 T 12-10-2018 VAPA_1c15210 48532e87ad549b023a06debc16732399 602 Pfam PF00890 FAD binding domain 14 409 2.5E-117 T 12-10-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 VAPA_1c52080 a1f5bbf774fd341b25c5341050830226 326 Gene3D G3DSA:1.10.10.10 234 324 2.5E-17 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c52080 a1f5bbf774fd341b25c5341050830226 326 SUPERFAMILY SSF46894 252 321 1.9E-16 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 VAPA_1c52080 a1f5bbf774fd341b25c5341050830226 326 Pfam PF00196 Bacterial regulatory proteins, luxR family 266 320 1.3E-14 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_1c52080 a1f5bbf774fd341b25c5341050830226 326 SMART SM00421 265 322 1.1E-16 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_1c52080 a1f5bbf774fd341b25c5341050830226 326 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 282 298 9.0E-9 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_1c52080 a1f5bbf774fd341b25c5341050830226 326 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 298 310 9.0E-9 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_1c52080 a1f5bbf774fd341b25c5341050830226 326 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 268 282 9.0E-9 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_2c04070 bc5a35d4d78326c5447d22d9d2984ae0 243 Pfam PF01292 Prokaryotic cytochrome b561 23 184 9.2E-25 T 12-10-2018 IPR011577 Cytochrome b561, bacterial/Ni-hydrogenase GO:0009055|GO:0016021 VAPA_2c04070 bc5a35d4d78326c5447d22d9d2984ae0 243 SUPERFAMILY SSF81342 18 187 5.41E-35 T 12-10-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 VAPA_2c04070 bc5a35d4d78326c5447d22d9d2984ae0 243 Gene3D G3DSA:1.20.950.20 18 173 4.8E-17 T 12-10-2018 VAPA_2c12120 772c55bab7d72d5dd0c942a55fd7767b 316 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 50 9.2E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_2c12120 772c55bab7d72d5dd0c942a55fd7767b 316 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 50 61 9.2E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_2c12120 772c55bab7d72d5dd0c942a55fd7767b 316 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 40 9.2E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_2c12120 772c55bab7d72d5dd0c942a55fd7767b 316 SUPERFAMILY SSF53850 99 308 1.32E-24 T 12-10-2018 VAPA_2c12120 772c55bab7d72d5dd0c942a55fd7767b 316 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 14 73 7.3E-17 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_2c12120 772c55bab7d72d5dd0c942a55fd7767b 316 Gene3D G3DSA:3.40.190.10 104 288 1.0E-30 T 12-10-2018 VAPA_2c12120 772c55bab7d72d5dd0c942a55fd7767b 316 SUPERFAMILY SSF46785 11 120 1.62E-21 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_2c12120 772c55bab7d72d5dd0c942a55fd7767b 316 Gene3D G3DSA:3.40.190.10 176 277 1.0E-30 T 12-10-2018 VAPA_2c12120 772c55bab7d72d5dd0c942a55fd7767b 316 Pfam PF03466 LysR substrate binding domain 98 304 5.1E-21 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_2c12120 772c55bab7d72d5dd0c942a55fd7767b 316 Gene3D G3DSA:1.10.10.10 11 99 2.3E-19 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_2c04470 d6d20ff89629f951c58b51f3bedba949 801 Gene3D G3DSA:3.20.70.20 6 600 1.6E-179 T 12-10-2018 VAPA_2c04470 d6d20ff89629f951c58b51f3bedba949 801 TIGRFAM TIGR02504 NrdJ_Z: ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent 31 591 1.0E-169 T 12-10-2018 IPR013344 Ribonucleotide reductase, adenosylcobalamin-dependent GO:0000166|GO:0004748|GO:0031419|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 VAPA_2c04470 d6d20ff89629f951c58b51f3bedba949 801 PRINTS PR01183 Ribonucleotide reductase large chain signature 369 391 7.7E-23 T 12-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 VAPA_2c04470 d6d20ff89629f951c58b51f3bedba949 801 PRINTS PR01183 Ribonucleotide reductase large chain signature 397 420 7.7E-23 T 12-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 VAPA_2c04470 d6d20ff89629f951c58b51f3bedba949 801 PRINTS PR01183 Ribonucleotide reductase large chain signature 171 190 7.7E-23 T 12-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 VAPA_2c04470 d6d20ff89629f951c58b51f3bedba949 801 PRINTS PR01183 Ribonucleotide reductase large chain signature 331 354 7.7E-23 T 12-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 VAPA_2c04470 d6d20ff89629f951c58b51f3bedba949 801 PRINTS PR01183 Ribonucleotide reductase large chain signature 453 480 7.7E-23 T 12-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 VAPA_2c04470 d6d20ff89629f951c58b51f3bedba949 801 SUPERFAMILY SSF51998 11 610 1.25E-168 T 12-10-2018 VAPA_2c04470 d6d20ff89629f951c58b51f3bedba949 801 Pfam PF02867 Ribonucleotide reductase, barrel domain 89 585 4.8E-128 T 12-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 VAPA_1c10580 a8a31ca9ec2e217c8f78b6fa328c2ac3 476 Hamap MF_01631 Bifunctional protein GlmU [glmU]. 11 470 39.783 T 12-10-2018 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|MetaCyc: PWY-5514 VAPA_1c10580 a8a31ca9ec2e217c8f78b6fa328c2ac3 476 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 413 447 5.9E-6 T 12-10-2018 IPR001451 Hexapeptide repeat VAPA_1c10580 a8a31ca9ec2e217c8f78b6fa328c2ac3 476 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 297 330 2.6E-5 T 12-10-2018 IPR001451 Hexapeptide repeat VAPA_1c10580 a8a31ca9ec2e217c8f78b6fa328c2ac3 476 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 335 369 6.4E-6 T 12-10-2018 IPR001451 Hexapeptide repeat VAPA_1c10580 a8a31ca9ec2e217c8f78b6fa328c2ac3 476 Pfam PF12804 MobA-like NTP transferase domain 14 147 1.3E-19 T 12-10-2018 IPR025877 MobA-like NTP transferase VAPA_1c10580 a8a31ca9ec2e217c8f78b6fa328c2ac3 476 SUPERFAMILY SSF51161 269 456 1.54E-44 T 12-10-2018 IPR011004 Trimeric LpxA-like superfamily VAPA_1c10580 a8a31ca9ec2e217c8f78b6fa328c2ac3 476 Gene3D G3DSA:3.90.550.10 8 241 2.5E-60 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases VAPA_1c10580 a8a31ca9ec2e217c8f78b6fa328c2ac3 476 Gene3D G3DSA:2.160.10.10 243 474 1.5E-62 T 12-10-2018 VAPA_1c10580 a8a31ca9ec2e217c8f78b6fa328c2ac3 476 TIGRFAM TIGR01173 glmU: UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase 13 473 6.3E-176 T 12-10-2018 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|MetaCyc: PWY-5514 VAPA_1c10580 a8a31ca9ec2e217c8f78b6fa328c2ac3 476 SUPERFAMILY SSF53448 12 266 3.6E-60 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases VAPA_1c16670 78a1e6171a3827d051c74b8483e2d87e 360 PIRSF PIRSF039026 1 357 1.7E-119 T 12-10-2018 IPR026289 Solute binding protein, mannitol/chloroaromatic system-like VAPA_1c16670 78a1e6171a3827d051c74b8483e2d87e 360 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 37 318 4.4E-62 T 12-10-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0030288|GO:0055085 VAPA_1c16670 78a1e6171a3827d051c74b8483e2d87e 360 Gene3D G3DSA:3.40.190.10 151 323 6.0E-124 T 12-10-2018 VAPA_1c16670 78a1e6171a3827d051c74b8483e2d87e 360 Gene3D G3DSA:3.40.190.170 32 337 6.0E-124 T 12-10-2018 IPR038404 TRAP transporter solute receptor DctP superfamily VAPA_1c53850 f5125cd3a8c4ef78a0f0ee85d0b731ec 224 Pfam PF13489 Methyltransferase domain 39 158 1.2E-11 T 12-10-2018 VAPA_1c53850 f5125cd3a8c4ef78a0f0ee85d0b731ec 224 SUPERFAMILY SSF53335 32 218 4.14E-19 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase VAPA_1c53850 f5125cd3a8c4ef78a0f0ee85d0b731ec 224 Gene3D G3DSA:3.40.50.150 8 210 2.2E-15 T 12-10-2018 VAPA_1c19260 6419757a532a90ca7188a0e0d38a78fc 606 ProSitePatterns PS00455 Putative AMP-binding domain signature. 194 205 - T 12-10-2018 IPR020845 AMP-binding, conserved site VAPA_1c19260 6419757a532a90ca7188a0e0d38a78fc 606 Gene3D G3DSA:3.40.50.12780 337 468 2.1E-29 T 12-10-2018 VAPA_1c19260 6419757a532a90ca7188a0e0d38a78fc 606 SUPERFAMILY SSF56801 9 604 2.49E-108 T 12-10-2018 VAPA_1c19260 6419757a532a90ca7188a0e0d38a78fc 606 Pfam PF00501 AMP-binding enzyme 16 475 2.6E-83 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 VAPA_1c19260 6419757a532a90ca7188a0e0d38a78fc 606 Gene3D G3DSA:3.40.50.12780 2 336 9.1E-50 T 12-10-2018 VAPA_1c29250 518293abb9787c633511834437b422c8 159 Gene3D G3DSA:3.40.630.30 8 145 2.4E-23 T 12-10-2018 VAPA_1c29250 518293abb9787c633511834437b422c8 159 SUPERFAMILY SSF55729 11 141 4.09E-23 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase VAPA_1c29250 518293abb9787c633511834437b422c8 159 Pfam PF00583 Acetyltransferase (GNAT) family 57 140 4.9E-11 T 12-10-2018 IPR000182 GNAT domain VAPA_1c29580 e2172838b2b335c86c78cf80a88e1234 737 SMART SM00316 574 657 1.9E-10 T 12-10-2018 IPR022967 RNA-binding domain, S1 VAPA_1c29580 e2172838b2b335c86c78cf80a88e1234 737 ProSitePatterns PS01175 Ribonuclease II family signature. 461 485 - T 12-10-2018 IPR022966 Ribonuclease II/R, conserved site VAPA_1c29580 e2172838b2b335c86c78cf80a88e1234 737 Hamap MF_01895 Ribonuclease R [rnr]. 1 657 51.665 T 12-10-2018 IPR011805 Ribonuclease R GO:0003723|GO:0004518 VAPA_1c29580 e2172838b2b335c86c78cf80a88e1234 737 Gene3D G3DSA:2.40.50.140 1 49 3.6E-10 T 12-10-2018 VAPA_1c29580 e2172838b2b335c86c78cf80a88e1234 737 Pfam PF00575 S1 RNA binding domain 576 654 3.1E-9 T 12-10-2018 IPR003029 S1 domain GO:0003676 VAPA_1c29580 e2172838b2b335c86c78cf80a88e1234 737 SUPERFAMILY SSF50249 2 49 6.17E-8 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold VAPA_1c29580 e2172838b2b335c86c78cf80a88e1234 737 TIGRFAM TIGR00358 3_prime_RNase: VacB and RNase II family 3'-5' exoribonucleases 3 657 8.1E-189 T 12-10-2018 IPR004476 Ribonuclease II/ribonuclease R GO:0003723|GO:0004540|GO:0016070 VAPA_1c29580 e2172838b2b335c86c78cf80a88e1234 737 Pfam PF00773 RNB domain 162 493 1.2E-101 T 12-10-2018 IPR001900 Ribonuclease II/R GO:0003723|GO:0004540 VAPA_1c29580 e2172838b2b335c86c78cf80a88e1234 737 SUPERFAMILY SSF50249 576 656 4.66E-18 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold VAPA_1c29580 e2172838b2b335c86c78cf80a88e1234 737 TIGRFAM TIGR02063 RNase_R: ribonuclease R 5 496 5.4E-184 T 12-10-2018 IPR011805 Ribonuclease R GO:0003723|GO:0004518 VAPA_1c29580 e2172838b2b335c86c78cf80a88e1234 737 Gene3D G3DSA:2.40.50.140 577 689 8.7E-19 T 12-10-2018 VAPA_1c29580 e2172838b2b335c86c78cf80a88e1234 737 SUPERFAMILY SSF50249 89 574 3.24E-137 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold VAPA_1c29580 e2172838b2b335c86c78cf80a88e1234 737 SMART SM00955 162 494 4.1E-173 T 12-10-2018 IPR001900 Ribonuclease II/R GO:0003723|GO:0004540 VAPA_1c29580 e2172838b2b335c86c78cf80a88e1234 737 Pfam PF08206 Ribonuclease B OB domain 1 46 4.1E-13 T 12-10-2018 IPR013223 Ribonuclease B, N-terminal OB domain VAPA_1c06810 cc071257a3058ec6f62436b46bd2bda8 395 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 62 378 2.8E-56 T 12-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 VAPA_1c06810 cc071257a3058ec6f62436b46bd2bda8 395 Gene3D G3DSA:2.40.420.20 57 363 6.0E-55 T 12-10-2018 VAPA_1c06810 cc071257a3058ec6f62436b46bd2bda8 395 Gene3D G3DSA:1.10.287.470 118 189 6.0E-55 T 12-10-2018 VAPA_1c06810 cc071257a3058ec6f62436b46bd2bda8 395 Gene3D G3DSA:2.40.30.170 69 301 6.0E-55 T 12-10-2018 VAPA_1c06810 cc071257a3058ec6f62436b46bd2bda8 395 SUPERFAMILY SSF111369 71 258 4.18E-18 T 12-10-2018 VAPA_1c06810 cc071257a3058ec6f62436b46bd2bda8 395 Gene3D G3DSA:2.40.50.100 83 224 6.0E-55 T 12-10-2018 VAPA_1c06810 cc071257a3058ec6f62436b46bd2bda8 395 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 74 279 3.1E-14 T 12-10-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain VAPA_1c15040 2a231f6b5d84d1ed58ca513b4980d60e 223 SMART SM00464 17 218 1.4E-11 T 12-10-2018 IPR003111 Lon, substrate-binding domain VAPA_1c15040 2a231f6b5d84d1ed58ca513b4980d60e 223 Gene3D G3DSA:1.10.4060.10 130 223 2.8E-34 T 12-10-2018 VAPA_1c15040 2a231f6b5d84d1ed58ca513b4980d60e 223 Pfam PF02190 ATP-dependent protease La (LON) substrate-binding domain 18 217 3.6E-25 T 12-10-2018 IPR003111 Lon, substrate-binding domain VAPA_1c15040 2a231f6b5d84d1ed58ca513b4980d60e 223 SUPERFAMILY SSF88697 17 216 1.19E-48 T 12-10-2018 IPR015947 PUA-like superfamily VAPA_1c15040 2a231f6b5d84d1ed58ca513b4980d60e 223 Gene3D G3DSA:2.30.130.40 15 129 6.0E-40 T 12-10-2018 VAPA_2c04820 d7e307a616c455d02f50b762b8cfac34 394 Gene3D G3DSA:3.40.47.10 128 390 1.3E-137 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 VAPA_2c04820 d7e307a616c455d02f50b762b8cfac34 394 Pfam PF02803 Thiolase, C-terminal domain 271 392 1.7E-40 T 12-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 VAPA_2c04820 d7e307a616c455d02f50b762b8cfac34 394 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 12 392 7.6E-127 T 12-10-2018 IPR002155 Thiolase GO:0016747 VAPA_2c04820 d7e307a616c455d02f50b762b8cfac34 394 ProSitePatterns PS00099 Thiolases active site. 375 388 - T 12-10-2018 IPR020610 Thiolase, active site GO:0016747 VAPA_2c04820 d7e307a616c455d02f50b762b8cfac34 394 SUPERFAMILY SSF53901 6 268 3.13E-76 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 VAPA_2c04820 d7e307a616c455d02f50b762b8cfac34 394 Pfam PF00108 Thiolase, N-terminal domain 7 262 5.7E-81 T 12-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 VAPA_2c04820 d7e307a616c455d02f50b762b8cfac34 394 Gene3D G3DSA:3.40.47.10 11 277 1.3E-137 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 VAPA_2c04820 d7e307a616c455d02f50b762b8cfac34 394 SUPERFAMILY SSF53901 272 392 1.92E-39 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 VAPA_2c04820 d7e307a616c455d02f50b762b8cfac34 394 PIRSF PIRSF000429 1 394 1.1E-113 T 12-10-2018 IPR002155 Thiolase GO:0016747 VAPA_2c04820 d7e307a616c455d02f50b762b8cfac34 394 ProSitePatterns PS00737 Thiolases signature 2. 340 356 - T 12-10-2018 IPR020613 Thiolase, conserved site GO:0016747 VAPA_1c41230 1c9a95758b292953b7dcca5179af2de6 290 Gene3D G3DSA:3.40.190.10 162 255 1.0E-47 T 12-10-2018 VAPA_1c41230 1c9a95758b292953b7dcca5179af2de6 290 SUPERFAMILY SSF46785 4 111 5.62E-22 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c41230 1c9a95758b292953b7dcca5179af2de6 290 Gene3D G3DSA:3.40.190.10 96 261 1.0E-47 T 12-10-2018 VAPA_1c41230 1c9a95758b292953b7dcca5179af2de6 290 Pfam PF03466 LysR substrate binding domain 88 281 1.4E-23 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_1c41230 1c9a95758b292953b7dcca5179af2de6 290 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 32 42 8.3E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c41230 1c9a95758b292953b7dcca5179af2de6 290 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 53 8.3E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c41230 1c9a95758b292953b7dcca5179af2de6 290 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 21 32 8.3E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c41230 1c9a95758b292953b7dcca5179af2de6 290 SUPERFAMILY SSF53850 89 282 2.71E-26 T 12-10-2018 VAPA_1c41230 1c9a95758b292953b7dcca5179af2de6 290 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 65 9.5E-18 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c41230 1c9a95758b292953b7dcca5179af2de6 290 Gene3D G3DSA:1.10.10.10 1 86 7.1E-24 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c44910 c12bbf7ef6e98bd03e541e6122b5537f 199 SUPERFAMILY SSF52972 1 195 5.76E-58 T 12-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like VAPA_1c44910 c12bbf7ef6e98bd03e541e6122b5537f 199 Gene3D G3DSA:3.90.950.10 1 199 9.5E-60 T 12-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like VAPA_1c44910 c12bbf7ef6e98bd03e541e6122b5537f 199 Pfam PF01725 Ham1 family 3 192 1.2E-44 T 12-10-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 KEGG: 00230+3.6.1.66|Reactome: R-HSA-74259 VAPA_1c44910 c12bbf7ef6e98bd03e541e6122b5537f 199 Hamap MF_01405 dITP/XTP pyrophosphatase. 1 196 38.775 T 12-10-2018 IPR020922 dITP/XTP pyrophosphatase GO:0009143|GO:0017111 KEGG: 00230+3.6.1.66 VAPA_1c47590 c185ac66ef9fe3a9745adb79b94c87f5 515 Pfam PF00875 DNA photolyase 16 176 5.0E-50 T 12-10-2018 IPR006050 DNA photolyase, N-terminal Reactome: R-HSA-400253 VAPA_1c47590 c185ac66ef9fe3a9745adb79b94c87f5 515 Gene3D G3DSA:1.10.579.10 308 495 4.0E-78 T 12-10-2018 VAPA_1c47590 c185ac66ef9fe3a9745adb79b94c87f5 515 PRINTS PR00147 DNA photolyase signature 151 167 6.9E-27 T 12-10-2018 IPR002081 Cryptochrome/DNA photolyase class 1 VAPA_1c47590 c185ac66ef9fe3a9745adb79b94c87f5 515 PRINTS PR00147 DNA photolyase signature 360 378 6.9E-27 T 12-10-2018 IPR002081 Cryptochrome/DNA photolyase class 1 VAPA_1c47590 c185ac66ef9fe3a9745adb79b94c87f5 515 PRINTS PR00147 DNA photolyase signature 340 356 6.9E-27 T 12-10-2018 IPR002081 Cryptochrome/DNA photolyase class 1 VAPA_1c47590 c185ac66ef9fe3a9745adb79b94c87f5 515 PRINTS PR00147 DNA photolyase signature 399 413 6.9E-27 T 12-10-2018 IPR002081 Cryptochrome/DNA photolyase class 1 VAPA_1c47590 c185ac66ef9fe3a9745adb79b94c87f5 515 Gene3D G3DSA:1.25.40.80 140 298 8.0E-74 T 12-10-2018 VAPA_1c47590 c185ac66ef9fe3a9745adb79b94c87f5 515 SUPERFAMILY SSF52425 14 191 3.53E-55 T 12-10-2018 IPR036155 Cryptochrome/photolyase, N-terminal domain superfamily Reactome: R-HSA-400253 VAPA_1c47590 c185ac66ef9fe3a9745adb79b94c87f5 515 ProSitePatterns PS00691 DNA photolyases class 1 signature 2. 360 379 - T 12-10-2018 IPR018394 Cryptochrome/DNA photolyase class 1, conserved site, C-terminal VAPA_1c47590 c185ac66ef9fe3a9745adb79b94c87f5 515 SUPERFAMILY SSF48173 205 494 3.92E-101 T 12-10-2018 IPR036134 Cryptochrome/DNA photolyase, FAD-binding domain-like superfamily Reactome: R-HSA-400253 VAPA_1c47590 c185ac66ef9fe3a9745adb79b94c87f5 515 Pfam PF03441 FAD binding domain of DNA photolyase 284 490 3.5E-85 T 12-10-2018 IPR005101 Cryptochrome/DNA photolyase, FAD-binding domain Reactome: R-HSA-400253 VAPA_1c47590 c185ac66ef9fe3a9745adb79b94c87f5 515 Gene3D G3DSA:3.40.50.620 16 218 8.0E-74 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold VAPA_1c50010 bdc3fd3b14affeb1d7d38c567e055214 429 Pfam PF00529 HlyD membrane-fusion protein of T1SS 50 374 7.1E-9 T 12-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 VAPA_1c50010 bdc3fd3b14affeb1d7d38c567e055214 429 Gene3D G3DSA:2.40.30.170 66 318 1.6E-104 T 12-10-2018 VAPA_1c50010 bdc3fd3b14affeb1d7d38c567e055214 429 Gene3D G3DSA:2.40.50.100 77 221 1.6E-104 T 12-10-2018 VAPA_1c50010 bdc3fd3b14affeb1d7d38c567e055214 429 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 74 308 1.4E-12 T 12-10-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain VAPA_1c50010 bdc3fd3b14affeb1d7d38c567e055214 429 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 55 391 3.5E-78 T 12-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 VAPA_1c50010 bdc3fd3b14affeb1d7d38c567e055214 429 Gene3D G3DSA:1.10.287.470 112 185 1.6E-104 T 12-10-2018 VAPA_1c50010 bdc3fd3b14affeb1d7d38c567e055214 429 Gene3D G3DSA:2.40.420.20 319 382 1.6E-104 T 12-10-2018 VAPA_1c50010 bdc3fd3b14affeb1d7d38c567e055214 429 SUPERFAMILY SSF111369 66 314 9.81E-77 T 12-10-2018 VAPA_2c12530 bfca62bc813e550892c9aa77b911f2ef 355 SUPERFAMILY SSF52540 4 240 3.3E-85 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_2c12530 bfca62bc813e550892c9aa77b911f2ef 355 SUPERFAMILY SSF50331 237 349 5.44E-13 T 12-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal VAPA_2c12530 bfca62bc813e550892c9aa77b911f2ef 355 Pfam PF00005 ABC transporter 20 161 6.2E-34 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_2c12530 bfca62bc813e550892c9aa77b911f2ef 355 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_2c12530 bfca62bc813e550892c9aa77b911f2ef 355 Pfam PF08402 TOBE domain 277 348 3.4E-12 T 12-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 VAPA_2c12530 bfca62bc813e550892c9aa77b911f2ef 355 SMART SM00382 28 211 3.9E-18 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_2c12530 bfca62bc813e550892c9aa77b911f2ef 355 Gene3D G3DSA:3.40.50.300 2 270 2.9E-76 T 12-10-2018 VAPA_1c23700 b9d58ec4916be6f0e03463a1535807f0 380 SUPERFAMILY SSF50998 36 369 2.92E-51 T 12-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily VAPA_1c23700 b9d58ec4916be6f0e03463a1535807f0 380 Pfam PF13360 PQQ-like domain 78 305 5.1E-49 T 12-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat VAPA_1c23700 b9d58ec4916be6f0e03463a1535807f0 380 Gene3D G3DSA:2.130.10.10 25 378 3.7E-66 T 12-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 VAPA_1c23700 b9d58ec4916be6f0e03463a1535807f0 380 SMART SM00564 142 174 530.0 T 12-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat VAPA_1c23700 b9d58ec4916be6f0e03463a1535807f0 380 SMART SM00564 317 348 25.0 T 12-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat VAPA_1c23700 b9d58ec4916be6f0e03463a1535807f0 380 SMART SM00564 65 96 0.36 T 12-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat VAPA_1c23700 b9d58ec4916be6f0e03463a1535807f0 380 SMART SM00564 275 307 350.0 T 12-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat VAPA_1c23700 b9d58ec4916be6f0e03463a1535807f0 380 SMART SM00564 181 218 63.0 T 12-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat VAPA_1c23700 b9d58ec4916be6f0e03463a1535807f0 380 Hamap MF_00923 Outer membrane protein assembly factor BamB [bamB]. 10 379 27.862 T 12-10-2018 IPR017687 Outer membrane protein assembly factor BamB VAPA_1c23700 b9d58ec4916be6f0e03463a1535807f0 380 TIGRFAM TIGR03300 assembly_YfgL: outer membrane assembly lipoprotein YfgL 17 377 1.6E-94 T 12-10-2018 IPR017687 Outer membrane protein assembly factor BamB VAPA_1c03750 e4cd2c642a50518d2a630356805daf0b 512 SUPERFAMILY SSF53720 29 496 1.96E-127 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 VAPA_1c03750 e4cd2c642a50518d2a630356805daf0b 512 Gene3D G3DSA:3.40.309.10 267 461 4.1E-132 T 12-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 VAPA_1c03750 e4cd2c642a50518d2a630356805daf0b 512 Gene3D G3DSA:3.40.605.10 33 486 4.1E-132 T 12-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 VAPA_1c03750 e4cd2c642a50518d2a630356805daf0b 512 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 263 270 - T 12-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 VAPA_1c03750 e4cd2c642a50518d2a630356805daf0b 512 Pfam PF00171 Aldehyde dehydrogenase family 31 489 2.5E-123 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 VAPA_1c13050 8d1cf9b4f7ad30852600edc452c5767b 200 Gene3D G3DSA:2.160.10.10 3 173 1.0E-48 T 12-10-2018 VAPA_1c13050 8d1cf9b4f7ad30852600edc452c5767b 200 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 88 121 9.3E-5 T 12-10-2018 IPR001451 Hexapeptide repeat VAPA_1c13050 8d1cf9b4f7ad30852600edc452c5767b 200 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 17 44 2.6E-5 T 12-10-2018 IPR001451 Hexapeptide repeat VAPA_1c13050 8d1cf9b4f7ad30852600edc452c5767b 200 SUPERFAMILY SSF51161 2 163 1.8E-41 T 12-10-2018 IPR011004 Trimeric LpxA-like superfamily VAPA_2c06760 3aab9846e72e44eaa09f851e5f0cc34d 68 Pfam PF10932 Protein of unknown function (DUF2783) 9 67 5.6E-28 T 12-10-2018 IPR021233 Protein of unknown function DUF2783 VAPA_1c29150 e07c889d9f3b2eed0121db72d3e5502f 329 Gene3D G3DSA:3.40.50.1170 7 205 9.3E-68 T 12-10-2018 IPR037152 L-asparaginase, N-terminal domain superfamily Reactome: R-HSA-70614 VAPA_1c29150 e07c889d9f3b2eed0121db72d3e5502f 329 Gene3D G3DSA:3.40.50.40 224 329 5.4E-25 T 12-10-2018 IPR027473 L-asparaginase, C-terminal Reactome: R-HSA-70614 VAPA_1c29150 e07c889d9f3b2eed0121db72d3e5502f 329 SMART SM00870 11 327 4.1E-104 T 12-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 VAPA_1c29150 e07c889d9f3b2eed0121db72d3e5502f 329 Pfam PF00710 Asparaginase, N-terminal 11 196 1.5E-51 T 12-10-2018 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 VAPA_1c29150 e07c889d9f3b2eed0121db72d3e5502f 329 SUPERFAMILY SSF53774 6 324 1.96E-78 T 12-10-2018 IPR036152 Asparaginase/glutaminase-like superfamily Reactome: R-HSA-70614 VAPA_1c29150 e07c889d9f3b2eed0121db72d3e5502f 329 ProSitePatterns PS00144 Asparaginase / glutaminase active site signature 1. 14 22 - T 12-10-2018 IPR020827 Asparaginase/glutaminase, active site 1 GO:0006520 VAPA_1c29150 e07c889d9f3b2eed0121db72d3e5502f 329 ProSitePatterns PS00917 Asparaginase / glutaminase active site signature 2. 92 102 - T 12-10-2018 IPR027475 Asparaginase/glutaminase, active site 2 Reactome: R-HSA-70614 VAPA_1c29150 e07c889d9f3b2eed0121db72d3e5502f 329 PRINTS PR00139 Asparaginase/glutaminase family signature 91 109 6.3E-21 T 12-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 VAPA_1c29150 e07c889d9f3b2eed0121db72d3e5502f 329 PRINTS PR00139 Asparaginase/glutaminase family signature 278 296 6.3E-21 T 12-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 VAPA_1c29150 e07c889d9f3b2eed0121db72d3e5502f 329 PRINTS PR00139 Asparaginase/glutaminase family signature 12 23 6.3E-21 T 12-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 VAPA_1c29150 e07c889d9f3b2eed0121db72d3e5502f 329 PIRSF PIRSF001220 7 328 4.1E-64 T 12-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 VAPA_1c29150 e07c889d9f3b2eed0121db72d3e5502f 329 PIRSF PIRSF500176 8 328 5.7E-60 T 12-10-2018 VAPA_1c34380 167279b86a320ab10a11ddf7ecd78257 302 Pfam PF03466 LysR substrate binding domain 95 296 6.0E-25 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_1c34380 167279b86a320ab10a11ddf7ecd78257 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 44 55 8.6E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c34380 167279b86a320ab10a11ddf7ecd78257 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 23 34 8.6E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c34380 167279b86a320ab10a11ddf7ecd78257 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 44 8.6E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c34380 167279b86a320ab10a11ddf7ecd78257 302 SUPERFAMILY SSF53850 89 297 1.99E-39 T 12-10-2018 VAPA_1c34380 167279b86a320ab10a11ddf7ecd78257 302 Gene3D G3DSA:3.40.190.10 89 295 4.9E-63 T 12-10-2018 VAPA_1c34380 167279b86a320ab10a11ddf7ecd78257 302 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 65 1.7E-17 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c34380 167279b86a320ab10a11ddf7ecd78257 302 Gene3D G3DSA:1.10.10.10 1 87 1.8E-28 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c34380 167279b86a320ab10a11ddf7ecd78257 302 Gene3D G3DSA:3.40.190.10 170 270 4.9E-63 T 12-10-2018 VAPA_1c34380 167279b86a320ab10a11ddf7ecd78257 302 SUPERFAMILY SSF46785 3 85 3.11E-20 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c02510 48c3fcdf7b0efdd989c55562ac637a66 717 Pfam PF00069 Protein kinase domain 34 255 3.3E-27 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 VAPA_1c02510 48c3fcdf7b0efdd989c55562ac637a66 717 Gene3D G3DSA:1.10.510.10 135 306 1.1E-47 T 12-10-2018 VAPA_1c02510 48c3fcdf7b0efdd989c55562ac637a66 717 Gene3D G3DSA:3.30.200.20 16 134 1.1E-47 T 12-10-2018 VAPA_1c02510 48c3fcdf7b0efdd989c55562ac637a66 717 SMART SM00219 34 306 6.3E-5 T 12-10-2018 IPR020635 Tyrosine-protein kinase, catalytic domain GO:0004713|GO:0006468 VAPA_1c02510 48c3fcdf7b0efdd989c55562ac637a66 717 SUPERFAMILY SSF56112 9 303 1.15E-45 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily VAPA_1c02510 48c3fcdf7b0efdd989c55562ac637a66 717 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 40 63 - T 12-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 VAPA_1c02510 48c3fcdf7b0efdd989c55562ac637a66 717 ProSitePatterns PS00109 Tyrosine protein kinases specific active-site signature. 172 184 - T 12-10-2018 IPR008266 Tyrosine-protein kinase, active site GO:0004672|GO:0006468 VAPA_1c25230 da256539bfb20e02a584d98486f5e488 256 SUPERFAMILY SSF46785 10 79 8.88E-8 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c25230 da256539bfb20e02a584d98486f5e488 256 Gene3D G3DSA:1.10.10.10 2 68 5.6E-14 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c25230 da256539bfb20e02a584d98486f5e488 256 TIGRFAM TIGR02431 pcaR_pcaU: beta-ketoadipate pathway transcriptional regulators, PcaR/PcaU/PobR family 6 256 4.7E-90 T 12-10-2018 IPR012794 Beta-ketoadipate transcriptional regulator, PcaR/PcaU/PobR GO:0003677|GO:0045893|GO:0046278 VAPA_1c25230 da256539bfb20e02a584d98486f5e488 256 Pfam PF09339 IclR helix-turn-helix domain 12 62 3.0E-12 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 VAPA_1c25230 da256539bfb20e02a584d98486f5e488 256 SUPERFAMILY SSF55781 78 255 1.08E-40 T 12-10-2018 VAPA_1c25230 da256539bfb20e02a584d98486f5e488 256 Pfam PF01614 Bacterial transcriptional regulator 129 253 1.3E-35 T 12-10-2018 IPR014757 Transcription regulator IclR, C-terminal VAPA_1c25230 da256539bfb20e02a584d98486f5e488 256 SMART SM00346 9 97 7.3E-20 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 VAPA_1c25230 da256539bfb20e02a584d98486f5e488 256 Gene3D G3DSA:3.30.450.40 77 256 2.0E-52 T 12-10-2018 IPR029016 GAF-like domain superfamily VAPA_1c37610 d5997d47949bfc6c5bdd7676e7b52b67 301 SUPERFAMILY SSF53850 87 294 9.41E-28 T 12-10-2018 VAPA_1c37610 d5997d47949bfc6c5bdd7676e7b52b67 301 Gene3D G3DSA:1.10.10.10 1 88 1.9E-27 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c37610 d5997d47949bfc6c5bdd7676e7b52b67 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 8.1E-7 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c37610 d5997d47949bfc6c5bdd7676e7b52b67 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 8.1E-7 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c37610 d5997d47949bfc6c5bdd7676e7b52b67 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 8.1E-7 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c37610 d5997d47949bfc6c5bdd7676e7b52b67 301 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 3.3E-21 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c37610 d5997d47949bfc6c5bdd7676e7b52b67 301 SUPERFAMILY SSF46785 1 109 8.82E-25 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c37610 d5997d47949bfc6c5bdd7676e7b52b67 301 Gene3D G3DSA:3.40.190.10 98 285 7.0E-45 T 12-10-2018 VAPA_1c37610 d5997d47949bfc6c5bdd7676e7b52b67 301 Gene3D G3DSA:3.40.190.10 165 267 7.0E-45 T 12-10-2018 VAPA_1c37610 d5997d47949bfc6c5bdd7676e7b52b67 301 Pfam PF03466 LysR substrate binding domain 87 294 2.6E-26 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_1c44940 f28ba4511849b71607ecc553bf60af14 335 Pfam PF00069 Protein kinase domain 18 289 2.2E-37 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 VAPA_1c44940 f28ba4511849b71607ecc553bf60af14 335 Gene3D G3DSA:3.30.200.20 2 117 3.4E-17 T 12-10-2018 VAPA_1c44940 f28ba4511849b71607ecc553bf60af14 335 Gene3D G3DSA:1.10.510.10 119 301 1.6E-32 T 12-10-2018 VAPA_1c44940 f28ba4511849b71607ecc553bf60af14 335 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 160 172 - T 12-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 VAPA_1c44940 f28ba4511849b71607ecc553bf60af14 335 SUPERFAMILY SSF56112 14 291 3.78E-57 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily VAPA_1c44940 f28ba4511849b71607ecc553bf60af14 335 SMART SM00220 18 293 3.2E-38 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 VAPA_2c09280 18e05326d0512a9c5cc12bf6094dc8c0 345 SUPERFAMILY SSF46689 30 136 1.18E-18 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 VAPA_2c09280 18e05326d0512a9c5cc12bf6094dc8c0 345 Pfam PF13551 Winged helix-turn helix 35 92 7.7E-13 T 12-10-2018 VAPA_1c35720 b2806d62856c90eeb88b0dcbbf1a3d41 222 Pfam PF09335 SNARE associated Golgi protein 49 174 5.4E-22 T 12-10-2018 IPR032816 SNARE associated Golgi protein VAPA_1c20830 6748e93c225a65ccd0d0c43a0d34bc8b 267 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 17 241 3.5E-59 T 12-10-2018 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 VAPA_1c20830 6748e93c225a65ccd0d0c43a0d34bc8b 267 Gene3D G3DSA:3.20.20.60 2 260 8.7E-88 T 12-10-2018 VAPA_1c20830 6748e93c225a65ccd0d0c43a0d34bc8b 267 SUPERFAMILY SSF51621 2 253 1.29E-80 T 12-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 VAPA_1c20830 6748e93c225a65ccd0d0c43a0d34bc8b 267 TIGRFAM TIGR02311 HpaI: 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase 5 252 3.7E-114 T 12-10-2018 IPR012689 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase GO:0010124|GO:0018802 KEGG: 00350+4.1.2.52 VAPA_1c54770 d6e2634c191f7fee6a1d0f3e13c92a06 72 Pfam PF03994 Domain of Unknown Function (DUF350) 17 71 3.0E-17 T 12-10-2018 IPR007140 Protein of unknown function DUF350 VAPA_1c11450 1a645bad179446a235ee672c4e791809 528 PIRSF PIRSF002741 17 523 5.0E-86 T 12-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 VAPA_1c11450 1a645bad179446a235ee672c4e791809 528 Gene3D G3DSA:3.40.190.10 191 509 1.4E-118 T 12-10-2018 VAPA_1c11450 1a645bad179446a235ee672c4e791809 528 Gene3D G3DSA:3.10.105.10 266 502 1.4E-118 T 12-10-2018 VAPA_1c11450 1a645bad179446a235ee672c4e791809 528 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 69 441 1.5E-84 T 12-10-2018 IPR000914 Solute-binding protein family 5 domain VAPA_1c11450 1a645bad179446a235ee672c4e791809 528 Gene3D G3DSA:3.90.76.10 35 190 1.4E-118 T 12-10-2018 VAPA_1c11450 1a645bad179446a235ee672c4e791809 528 SUPERFAMILY SSF53850 24 527 7.06E-126 T 12-10-2018 VAPA_1c51480 e23835a6ff97eefd7f4728bcb847b383 380 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 327 336 - T 12-10-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 VAPA_1c51480 e23835a6ff97eefd7f4728bcb847b383 380 Pfam PF00067 Cytochrome P450 257 353 1.7E-11 T 12-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 VAPA_1c51480 e23835a6ff97eefd7f4728bcb847b383 380 Gene3D G3DSA:1.10.630.10 2 378 3.4E-60 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 VAPA_1c51480 e23835a6ff97eefd7f4728bcb847b383 380 SUPERFAMILY SSF48264 8 372 4.19E-47 T 12-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 VAPA_1c51480 e23835a6ff97eefd7f4728bcb847b383 380 PRINTS PR00359 B-class P450 signature 325 334 4.4E-16 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 VAPA_1c51480 e23835a6ff97eefd7f4728bcb847b383 380 PRINTS PR00359 B-class P450 signature 276 303 4.4E-16 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 VAPA_1c51480 e23835a6ff97eefd7f4728bcb847b383 380 PRINTS PR00359 B-class P450 signature 304 319 4.4E-16 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 VAPA_1c51480 e23835a6ff97eefd7f4728bcb847b383 380 PRINTS PR00359 B-class P450 signature 259 270 4.4E-16 T 12-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 VAPA_2c09650 88f40e3558c729aacc758da8bb317536 322 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 48 318 1.0E-80 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_2c09650 88f40e3558c729aacc758da8bb317536 322 Gene3D G3DSA:3.40.190.150 32 312 2.1E-102 T 12-10-2018 VAPA_2c09650 88f40e3558c729aacc758da8bb317536 322 SUPERFAMILY SSF53850 115 277 3.17E-14 T 12-10-2018 VAPA_2c09650 88f40e3558c729aacc758da8bb317536 322 Gene3D G3DSA:3.40.190.10 124 247 2.1E-102 T 12-10-2018 VAPA_2c09650 88f40e3558c729aacc758da8bb317536 322 PIRSF PIRSF017082 1 321 1.2E-75 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c38480 7121db4541bc66354d2a0bcfbbb38f85 512 Pfam PF02321 Outer membrane efflux protein 248 434 5.6E-27 T 12-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 VAPA_1c38480 7121db4541bc66354d2a0bcfbbb38f85 512 Pfam PF02321 Outer membrane efflux protein 31 224 4.1E-25 T 12-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 VAPA_1c38480 7121db4541bc66354d2a0bcfbbb38f85 512 SUPERFAMILY SSF56954 5 439 9.42E-88 T 12-10-2018 VAPA_1c38480 7121db4541bc66354d2a0bcfbbb38f85 512 TIGRFAM TIGR01844 type_I_sec_TolC: type I secretion outer membrane protein, TolC family 29 451 1.2E-95 T 12-10-2018 IPR010130 Type I secretion outer membrane protein, TolC GO:0015562|GO:0019867|GO:0055085 VAPA_1c38480 7121db4541bc66354d2a0bcfbbb38f85 512 Gene3D G3DSA:1.20.1600.10 29 459 5.1E-105 T 12-10-2018 VAPA_1c50470 2521459db6668b508da2ae456e1a764d 320 SUPERFAMILY SSF53822 9 314 7.57E-58 T 12-10-2018 IPR028082 Periplasmic binding protein-like I VAPA_1c50470 2521459db6668b508da2ae456e1a764d 320 Gene3D G3DSA:3.40.50.2300 137 313 8.2E-86 T 12-10-2018 VAPA_1c50470 2521459db6668b508da2ae456e1a764d 320 Gene3D G3DSA:3.40.50.2300 31 301 8.2E-86 T 12-10-2018 VAPA_1c50470 2521459db6668b508da2ae456e1a764d 320 Pfam PF13407 Periplasmic binding protein domain 47 292 5.6E-48 T 12-10-2018 IPR025997 Periplasmic binding protein VAPA_1c34010 7f906e8ad455a2ddf4a4f77443819d1c 271 PIRSF PIRSF029755 4 271 6.3E-119 T 12-10-2018 IPR016938 Uncharacterised protein family UPF0317 VAPA_1c34010 7f906e8ad455a2ddf4a4f77443819d1c 271 Gene3D G3DSA:3.40.1640.10 25 258 2.4E-93 T 12-10-2018 VAPA_1c34010 7f906e8ad455a2ddf4a4f77443819d1c 271 Pfam PF07286 Protein of unknown function (DUF1445) 120 262 4.0E-64 T 12-10-2018 IPR009906 D-glutamate cyclase VAPA_1c34010 7f906e8ad455a2ddf4a4f77443819d1c 271 SUPERFAMILY SSF160920 16 263 3.01E-110 T 12-10-2018 IPR038021 Putative hydro-lyase VAPA_1c34010 7f906e8ad455a2ddf4a4f77443819d1c 271 Gene3D G3DSA:3.30.2040.10 130 242 2.4E-93 T 12-10-2018 VAPA_1c34010 7f906e8ad455a2ddf4a4f77443819d1c 271 Hamap MF_01830 Putative hydro-lyase . 16 270 52.766 T 12-10-2018 IPR016938 Uncharacterised protein family UPF0317 VAPA_1c49580 66e5d0b6a437de020a482fd9af2c1615 1098 SUPERFAMILY SSF56059 82 332 6.89E-52 T 12-10-2018 VAPA_1c49580 66e5d0b6a437de020a482fd9af2c1615 1098 SMART SM00878 344 454 4.0E-45 T 12-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 VAPA_1c49580 66e5d0b6a437de020a482fd9af2c1615 1098 Gene3D G3DSA:2.40.50.100 485 560 7.7E-18 T 12-10-2018 VAPA_1c49580 66e5d0b6a437de020a482fd9af2c1615 1098 SUPERFAMILY SSF52096 583 841 2.09E-47 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily VAPA_1c49580 66e5d0b6a437de020a482fd9af2c1615 1098 Gene3D G3DSA:3.30.1490.20 130 204 6.0E-19 T 12-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 VAPA_1c49580 66e5d0b6a437de020a482fd9af2c1615 1098 SUPERFAMILY SSF51230 484 560 3.66E-16 T 12-10-2018 IPR011053 Single hybrid motif VAPA_1c49580 66e5d0b6a437de020a482fd9af2c1615 1098 Gene3D G3DSA:3.30.470.20 205 467 2.1E-91 T 12-10-2018 VAPA_1c49580 66e5d0b6a437de020a482fd9af2c1615 1098 SUPERFAMILY SSF52096 844 1084 1.17E-62 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily VAPA_1c49580 66e5d0b6a437de020a482fd9af2c1615 1098 SUPERFAMILY SSF51246 339 458 2.72E-29 T 12-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 VAPA_1c49580 66e5d0b6a437de020a482fd9af2c1615 1098 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 114 327 7.1E-56 T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 VAPA_1c49580 66e5d0b6a437de020a482fd9af2c1615 1098 Gene3D G3DSA:3.90.226.10 841 1080 2.0E-71 T 12-10-2018 VAPA_1c49580 66e5d0b6a437de020a482fd9af2c1615 1098 Pfam PF02785 Biotin carboxylase C-terminal domain 344 454 2.0E-29 T 12-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 VAPA_1c49580 66e5d0b6a437de020a482fd9af2c1615 1098 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 290 297 - T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 VAPA_1c49580 66e5d0b6a437de020a482fd9af2c1615 1098 Pfam PF00289 Biotin carboxylase, N-terminal domain 3 108 3.3E-39 T 12-10-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 VAPA_1c49580 66e5d0b6a437de020a482fd9af2c1615 1098 Gene3D G3DSA:3.90.226.10 576 840 3.7E-69 T 12-10-2018 VAPA_1c49580 66e5d0b6a437de020a482fd9af2c1615 1098 Pfam PF00364 Biotin-requiring enzyme 493 559 5.1E-11 T 12-10-2018 IPR000089 Biotin/lipoyl attachment VAPA_1c49580 66e5d0b6a437de020a482fd9af2c1615 1098 Gene3D G3DSA:3.40.50.20 2 129 2.2E-48 T 12-10-2018 VAPA_1c49580 66e5d0b6a437de020a482fd9af2c1615 1098 Pfam PF01039 Carboxyl transferase domain 606 1083 7.9E-68 T 12-10-2018 IPR034733 Acetyl-CoA carboxylase MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722|Reactome: R-HSA-196780 VAPA_1c49580 66e5d0b6a437de020a482fd9af2c1615 1098 SUPERFAMILY SSF52440 2 110 6.19E-39 T 12-10-2018 IPR016185 Pre-ATP-grasp domain superfamily VAPA_1c26380 cecb6b6bd6f5f6ba8f1f8363af8c2a88 548 Gene3D G3DSA:1.20.140.10 289 447 2.4E-38 T 12-10-2018 VAPA_1c26380 cecb6b6bd6f5f6ba8f1f8363af8c2a88 548 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 182 194 - T 12-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 VAPA_1c26380 cecb6b6bd6f5f6ba8f1f8363af8c2a88 548 SUPERFAMILY SSF56645 61 295 2.26E-30 T 12-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 VAPA_1c26380 cecb6b6bd6f5f6ba8f1f8363af8c2a88 548 SUPERFAMILY SSF47203 286 447 6.93E-40 T 12-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 VAPA_1c26380 cecb6b6bd6f5f6ba8f1f8363af8c2a88 548 Gene3D G3DSA:2.40.110.20 130 288 7.0E-54 T 12-10-2018 VAPA_1c26380 cecb6b6bd6f5f6ba8f1f8363af8c2a88 548 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 288 444 6.3E-31 T 12-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 VAPA_1c26380 cecb6b6bd6f5f6ba8f1f8363af8c2a88 548 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 180 277 4.1E-14 T 12-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 VAPA_1c14890 244d39d7a281854105437540d7790f22 221 Gene3D G3DSA:1.10.10.880 7 76 1.9E-9 T 12-10-2018 IPR036147 Anti sigma-E protein RseA, N-terminal domain superfamily GO:0016989 VAPA_1c14890 244d39d7a281854105437540d7790f22 221 Pfam PF03872 Anti sigma-E protein RseA, N-terminal domain 5 91 4.9E-15 T 12-10-2018 IPR005572 Anti sigma-E protein RseA, N-terminal GO:0016989 VAPA_1c14890 244d39d7a281854105437540d7790f22 221 SUPERFAMILY SSF89069 7 76 1.96E-11 T 12-10-2018 IPR036147 Anti sigma-E protein RseA, N-terminal domain superfamily GO:0016989 VAPA_1c54600 e816d647fb9cc7bb1140e2ad04e2412e 364 PIRSF PIRSF006232 30 341 8.2E-67 T 12-10-2018 IPR012093 Pirin Reactome: R-HSA-8935690 VAPA_1c54600 e816d647fb9cc7bb1140e2ad04e2412e 364 Gene3D G3DSA:2.60.120.10 175 302 5.4E-64 T 12-10-2018 IPR014710 RmlC-like jelly roll fold VAPA_1c54600 e816d647fb9cc7bb1140e2ad04e2412e 364 Gene3D G3DSA:2.60.120.10 79 328 5.4E-64 T 12-10-2018 IPR014710 RmlC-like jelly roll fold VAPA_1c54600 e816d647fb9cc7bb1140e2ad04e2412e 364 Pfam PF05726 Pirin C-terminal cupin domain 229 333 7.7E-21 T 12-10-2018 IPR008778 Pirin, C-terminal domain Reactome: R-HSA-8935690 VAPA_1c54600 e816d647fb9cc7bb1140e2ad04e2412e 364 Pfam PF02678 Pirin 78 153 2.8E-24 T 12-10-2018 IPR003829 Pirin, N-terminal domain Reactome: R-HSA-8935690 VAPA_1c54600 e816d647fb9cc7bb1140e2ad04e2412e 364 SUPERFAMILY SSF51182 79 338 1.42E-58 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily VAPA_1c47730 ef7da8e629f259bf3ea9c4dc9ee0a6bc 535 PIRSF PIRSF000414 1 535 1.7E-207 T 12-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 VAPA_1c47730 ef7da8e629f259bf3ea9c4dc9ee0a6bc 535 SUPERFAMILY SSF53927 218 535 3.61E-124 T 12-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 VAPA_1c47730 ef7da8e629f259bf3ea9c4dc9ee0a6bc 535 Gene3D G3DSA:3.40.140.20 398 535 3.5E-55 T 12-10-2018 IPR024051 AICAR transformylase, duplicated domain superfamily KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 VAPA_1c47730 ef7da8e629f259bf3ea9c4dc9ee0a6bc 535 Gene3D G3DSA:3.40.140.20 216 370 4.5E-60 T 12-10-2018 IPR024051 AICAR transformylase, duplicated domain superfamily KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 VAPA_1c47730 ef7da8e629f259bf3ea9c4dc9ee0a6bc 535 SUPERFAMILY SSF52335 3 191 2.22E-67 T 12-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily VAPA_1c47730 ef7da8e629f259bf3ea9c4dc9ee0a6bc 535 TIGRFAM TIGR00355 purH: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 4 535 2.3E-215 T 12-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 VAPA_1c47730 ef7da8e629f259bf3ea9c4dc9ee0a6bc 535 Pfam PF01808 AICARFT/IMPCHase bienzyme 134 465 1.3E-114 T 12-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 VAPA_1c47730 ef7da8e629f259bf3ea9c4dc9ee0a6bc 535 Hamap MF_00139 Bifunctional purine biosynthesis protein PurH [purH]. 2 535 43.787 T 12-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 VAPA_1c47730 ef7da8e629f259bf3ea9c4dc9ee0a6bc 535 SMART SM00851 14 129 1.8E-63 T 12-10-2018 IPR011607 Methylglyoxal synthase-like domain VAPA_1c47730 ef7da8e629f259bf3ea9c4dc9ee0a6bc 535 Gene3D G3DSA:3.40.50.1380 1 195 3.8E-82 T 12-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily VAPA_1c47730 ef7da8e629f259bf3ea9c4dc9ee0a6bc 535 Pfam PF02142 MGS-like domain 14 128 1.7E-31 T 12-10-2018 IPR011607 Methylglyoxal synthase-like domain VAPA_1c47730 ef7da8e629f259bf3ea9c4dc9ee0a6bc 535 SMART SM00798 134 467 1.9E-195 T 12-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 VAPA_2c09890 d22f93bd5e947391bf6b40156bc9c379 441 Gene3D G3DSA:3.50.50.60 19 233 4.0E-63 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_2c09890 d22f93bd5e947391bf6b40156bc9c379 441 Gene3D G3DSA:3.30.9.10 98 282 4.0E-63 T 12-10-2018 VAPA_2c09890 d22f93bd5e947391bf6b40156bc9c379 441 Gene3D G3DSA:3.50.50.60 373 413 1.0E-23 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_2c09890 d22f93bd5e947391bf6b40156bc9c379 441 SUPERFAMILY SSF51905 18 430 2.46E-60 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_2c09890 d22f93bd5e947391bf6b40156bc9c379 441 Pfam PF01266 FAD dependent oxidoreductase 19 412 1.9E-74 T 12-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 VAPA_2c09890 d22f93bd5e947391bf6b40156bc9c379 441 Gene3D G3DSA:3.30.9.10 333 372 1.0E-23 T 12-10-2018 VAPA_1c40880 61306d4b33bf779234971feedfdacaf6 234 Pfam PF07729 FCD domain 78 199 7.3E-15 T 12-10-2018 IPR011711 GntR, C-terminal VAPA_1c40880 61306d4b33bf779234971feedfdacaf6 234 Gene3D G3DSA:1.20.120.530 71 211 1.4E-21 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal VAPA_1c40880 61306d4b33bf779234971feedfdacaf6 234 Gene3D G3DSA:1.10.10.10 7 69 3.6E-20 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c40880 61306d4b33bf779234971feedfdacaf6 234 SUPERFAMILY SSF48008 74 206 1.2E-21 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal VAPA_1c40880 61306d4b33bf779234971feedfdacaf6 234 Pfam PF00392 Bacterial regulatory proteins, gntR family 9 68 8.9E-18 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_1c40880 61306d4b33bf779234971feedfdacaf6 234 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 28 42 1.0E-5 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_1c40880 61306d4b33bf779234971feedfdacaf6 234 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 42 58 1.0E-5 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_1c40880 61306d4b33bf779234971feedfdacaf6 234 SMART SM00895 78 201 6.3E-10 T 12-10-2018 IPR011711 GntR, C-terminal VAPA_1c40880 61306d4b33bf779234971feedfdacaf6 234 SUPERFAMILY SSF46785 9 72 2.28E-18 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c40880 61306d4b33bf779234971feedfdacaf6 234 SMART SM00345 10 68 3.1E-15 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_1c32540 4aa4d089ca8a289cb159b9f0de561c9a 570 SUPERFAMILY SSF52467 164 354 7.01E-33 T 12-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily VAPA_1c32540 4aa4d089ca8a289cb159b9f0de561c9a 570 Gene3D G3DSA:3.40.50.970 1 185 9.5E-47 T 12-10-2018 VAPA_1c32540 4aa4d089ca8a289cb159b9f0de561c9a 570 SUPERFAMILY SSF52518 5 190 4.87E-42 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold VAPA_1c32540 4aa4d089ca8a289cb159b9f0de561c9a 570 Gene3D G3DSA:3.40.50.970 363 540 5.3E-41 T 12-10-2018 VAPA_1c32540 4aa4d089ca8a289cb159b9f0de561c9a 570 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 10 179 5.4E-45 T 12-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 VAPA_1c32540 4aa4d089ca8a289cb159b9f0de561c9a 570 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 200 327 1.5E-18 T 12-10-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 VAPA_1c32540 4aa4d089ca8a289cb159b9f0de561c9a 570 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 408 536 1.8E-29 T 12-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 VAPA_1c32540 4aa4d089ca8a289cb159b9f0de561c9a 570 SUPERFAMILY SSF52518 364 538 7.63E-37 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold VAPA_1c32540 4aa4d089ca8a289cb159b9f0de561c9a 570 Gene3D G3DSA:3.40.50.1220 190 359 2.6E-29 T 12-10-2018 VAPA_1c14550 d39f9b6207fb1037a9e4c422f268e832 248 Pfam PF04397 LytTr DNA-binding domain 147 244 1.4E-21 T 12-10-2018 IPR007492 LytTR DNA-binding domain GO:0003677 VAPA_1c14550 d39f9b6207fb1037a9e4c422f268e832 248 Gene3D G3DSA:3.40.50.2300 1 134 4.3E-32 T 12-10-2018 VAPA_1c14550 d39f9b6207fb1037a9e4c422f268e832 248 SUPERFAMILY SSF52172 3 140 5.55E-33 T 12-10-2018 IPR011006 CheY-like superfamily VAPA_1c14550 d39f9b6207fb1037a9e4c422f268e832 248 Gene3D G3DSA:2.40.50.40 135 202 4.4E-9 T 12-10-2018 VAPA_1c14550 d39f9b6207fb1037a9e4c422f268e832 248 SMART SM00448 3 116 1.5E-26 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_1c14550 d39f9b6207fb1037a9e4c422f268e832 248 SMART SM00850 144 245 3.2E-26 T 12-10-2018 IPR007492 LytTR DNA-binding domain GO:0003677 VAPA_1c14550 d39f9b6207fb1037a9e4c422f268e832 248 Pfam PF00072 Response regulator receiver domain 6 116 4.5E-26 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_1c07860 32267311f2fe66cf47077e500b933b41 249 SUPERFAMILY SSF50447 1 73 1.13E-12 T 12-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily VAPA_1c07860 32267311f2fe66cf47077e500b933b41 249 Pfam PF01411 tRNA synthetases class II (A) 16 66 3.9E-8 T 12-10-2018 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 VAPA_1c07860 32267311f2fe66cf47077e500b933b41 249 Gene3D G3DSA:3.30.980.10 101 249 9.6E-28 T 12-10-2018 VAPA_1c07860 32267311f2fe66cf47077e500b933b41 249 SMART SM00863 196 244 1.8E-14 T 12-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 VAPA_1c07860 32267311f2fe66cf47077e500b933b41 249 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 196 244 1.6E-12 T 12-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 VAPA_1c07860 32267311f2fe66cf47077e500b933b41 249 SUPERFAMILY SSF55186 101 244 1.7E-26 T 12-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 VAPA_1c07860 32267311f2fe66cf47077e500b933b41 249 Gene3D G3DSA:2.40.30.130 1 82 4.3E-18 T 12-10-2018 VAPA_1c08590 bf5d62a94d70ea1d74927f8a7868682a 428 Pfam PF00330 Aconitase family (aconitate hydratase) 38 418 6.8E-83 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 VAPA_1c08590 bf5d62a94d70ea1d74927f8a7868682a 428 Gene3D G3DSA:3.30.499.20 13 278 2.0E-85 T 12-10-2018 VAPA_1c08590 bf5d62a94d70ea1d74927f8a7868682a 428 Gene3D G3DSA:3.30.499.10 281 428 3.5E-51 T 12-10-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 KEGG: 00290+4.2.1.33 VAPA_1c08590 bf5d62a94d70ea1d74927f8a7868682a 428 TIGRFAM TIGR01343 hacA_fam: homoaconitate hydratase family protein 13 424 3.3E-121 T 12-10-2018 IPR006251 Homoaconitase/3-isopropylmalate dehydratase, large subunit GO:0008652|GO:0016836|GO:0051539 KEGG: 00290+4.2.1.33 VAPA_1c08590 bf5d62a94d70ea1d74927f8a7868682a 428 PRINTS PR00415 Aconitase family signature 135 150 2.4E-19 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 VAPA_1c08590 bf5d62a94d70ea1d74927f8a7868682a 428 PRINTS PR00415 Aconitase family signature 197 210 2.4E-19 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 VAPA_1c08590 bf5d62a94d70ea1d74927f8a7868682a 428 PRINTS PR00415 Aconitase family signature 360 373 2.4E-19 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 VAPA_1c08590 bf5d62a94d70ea1d74927f8a7868682a 428 PRINTS PR00415 Aconitase family signature 121 134 2.4E-19 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 VAPA_1c08590 bf5d62a94d70ea1d74927f8a7868682a 428 PRINTS PR00415 Aconitase family signature 211 224 2.4E-19 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 VAPA_1c08590 bf5d62a94d70ea1d74927f8a7868682a 428 PRINTS PR00415 Aconitase family signature 110 118 2.4E-19 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 VAPA_1c08590 bf5d62a94d70ea1d74927f8a7868682a 428 SUPERFAMILY SSF53732 11 427 2.75E-122 T 12-10-2018 IPR036008 Aconitase, iron-sulfur domain KEGG: 00290+4.2.1.33 VAPA_1c25560 6c63a53c31682b2dc440b947b3f8c4f9 625 ProSitePatterns PS00211 ABC transporters family signature. 469 483 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_1c25560 6c63a53c31682b2dc440b947b3f8c4f9 625 SUPERFAMILY SSF52540 319 568 3.15E-71 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c25560 6c63a53c31682b2dc440b947b3f8c4f9 625 Gene3D G3DSA:3.40.50.300 11 314 2.8E-83 T 12-10-2018 VAPA_1c25560 6c63a53c31682b2dc440b947b3f8c4f9 625 Gene3D G3DSA:3.40.50.300 316 622 3.9E-86 T 12-10-2018 VAPA_1c25560 6c63a53c31682b2dc440b947b3f8c4f9 625 SMART SM00382 42 247 1.9E-15 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c25560 6c63a53c31682b2dc440b947b3f8c4f9 625 SMART SM00382 354 554 9.2E-15 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c25560 6c63a53c31682b2dc440b947b3f8c4f9 625 SUPERFAMILY SSF52540 13 269 6.01E-65 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c25560 6c63a53c31682b2dc440b947b3f8c4f9 625 ProSitePatterns PS00211 ABC transporters family signature. 170 184 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_1c25560 6c63a53c31682b2dc440b947b3f8c4f9 625 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 249 281 2.7E-7 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 VAPA_1c25560 6c63a53c31682b2dc440b947b3f8c4f9 625 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 548 594 2.7E-7 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 VAPA_1c25560 6c63a53c31682b2dc440b947b3f8c4f9 625 Pfam PF00005 ABC transporter 33 197 1.5E-25 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c25560 6c63a53c31682b2dc440b947b3f8c4f9 625 Pfam PF00005 ABC transporter 346 495 5.3E-31 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_2c11320 c72ccb5965ab1c811b3acd849a486a3d 411 Gene3D G3DSA:3.40.50.300 123 400 4.8E-58 T 12-10-2018 VAPA_2c11320 c72ccb5965ab1c811b3acd849a486a3d 411 Pfam PF13614 AAA domain 125 294 1.2E-32 T 12-10-2018 IPR025669 AAA domain VAPA_2c11320 c72ccb5965ab1c811b3acd849a486a3d 411 SUPERFAMILY SSF52540 123 393 8.33E-44 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c50720 6eb5761951df463cf86f8eec5a3b502f 347 SUPERFAMILY SSF50129 6 150 8.14E-35 T 12-10-2018 IPR011032 GroES-like superfamily VAPA_1c50720 6eb5761951df463cf86f8eec5a3b502f 347 Pfam PF00107 Zinc-binding dehydrogenase 165 302 1.0E-18 T 12-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 VAPA_1c50720 6eb5761951df463cf86f8eec5a3b502f 347 SMART SM00829 20 342 2.1E-4 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 VAPA_1c50720 6eb5761951df463cf86f8eec5a3b502f 347 SUPERFAMILY SSF51735 133 310 2.13E-45 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c50720 6eb5761951df463cf86f8eec5a3b502f 347 Gene3D G3DSA:3.40.50.720 133 313 6.5E-131 T 12-10-2018 VAPA_1c50720 6eb5761951df463cf86f8eec5a3b502f 347 Pfam PF16884 N-terminal domain of oxidoreductase 8 113 2.4E-35 T 12-10-2018 VAPA_1c50720 6eb5761951df463cf86f8eec5a3b502f 347 Gene3D G3DSA:3.90.180.10 22 341 6.5E-131 T 12-10-2018 VAPA_1c48260 d2a59045cbb9ec6a1435abd1e8a98b59 366 Hamap MF_01270 Anhydro-N-acetylmuramic acid kinase [anmK]. 1 366 38.458 T 12-10-2018 IPR005338 Anhydro-N-acetylmuramic acid kinase GO:0005524|GO:0006040|GO:0009254|GO:0016773 MetaCyc: PWY-7883 VAPA_1c48260 d2a59045cbb9ec6a1435abd1e8a98b59 366 Pfam PF03702 Anhydro-N-acetylmuramic acid kinase 1 366 7.1E-129 T 12-10-2018 IPR005338 Anhydro-N-acetylmuramic acid kinase GO:0005524|GO:0006040|GO:0009254|GO:0016773 MetaCyc: PWY-7883 VAPA_1c48260 d2a59045cbb9ec6a1435abd1e8a98b59 366 Gene3D G3DSA:3.30.420.40 138 326 1.2E-120 T 12-10-2018 VAPA_1c48260 d2a59045cbb9ec6a1435abd1e8a98b59 366 Gene3D G3DSA:3.30.420.40 2 361 1.2E-120 T 12-10-2018 VAPA_1c48260 d2a59045cbb9ec6a1435abd1e8a98b59 366 SUPERFAMILY SSF53067 62 337 4.75E-22 T 12-10-2018 VAPA_1c26290 ed65158f81c566d8a8a6f7f376230b2c 701 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 302 477 5.2E-62 T 12-10-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 VAPA_1c26290 ed65158f81c566d8a8a6f7f376230b2c 701 Gene3D G3DSA:3.90.226.10 3 298 8.2E-81 T 12-10-2018 VAPA_1c26290 ed65158f81c566d8a8a6f7f376230b2c 701 SUPERFAMILY SSF52096 9 293 1.63E-59 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily VAPA_1c26290 ed65158f81c566d8a8a6f7f376230b2c 701 Pfam PF00378 Enoyl-CoA hydratase/isomerase 10 163 1.2E-33 T 12-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 VAPA_1c26290 ed65158f81c566d8a8a6f7f376230b2c 701 Gene3D G3DSA:3.40.50.720 299 482 2.2E-66 T 12-10-2018 VAPA_1c26290 ed65158f81c566d8a8a6f7f376230b2c 701 SUPERFAMILY SSF48179 481 623 2.21E-27 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 VAPA_1c26290 ed65158f81c566d8a8a6f7f376230b2c 701 SUPERFAMILY SSF48179 604 700 1.79E-20 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 VAPA_1c26290 ed65158f81c566d8a8a6f7f376230b2c 701 SUPERFAMILY SSF51735 297 477 2.96E-57 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c26290 ed65158f81c566d8a8a6f7f376230b2c 701 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 610 698 1.1E-5 T 12-10-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 VAPA_1c26290 ed65158f81c566d8a8a6f7f376230b2c 701 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 482 574 4.5E-25 T 12-10-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 VAPA_1c26290 ed65158f81c566d8a8a6f7f376230b2c 701 Gene3D G3DSA:1.10.1040.50 484 700 2.1E-75 T 12-10-2018 VAPA_1c02380 e0353d74d000a3ab268b51a85d178ec6 850 Gene3D G3DSA:2.160.20.100 661 840 1.4E-25 T 12-10-2018 VAPA_1c02380 e0353d74d000a3ab268b51a85d178ec6 850 Gene3D G3DSA:2.160.20.80 497 660 1.5E-31 T 12-10-2018 VAPA_1c02380 e0353d74d000a3ab268b51a85d178ec6 850 Pfam PF13599 Pentapeptide repeats (9 copies) 735 813 4.2E-10 T 12-10-2018 IPR001646 Pentapeptide repeat VAPA_1c02380 e0353d74d000a3ab268b51a85d178ec6 850 Pfam PF13599 Pentapeptide repeats (9 copies) 593 659 2.1E-7 T 12-10-2018 IPR001646 Pentapeptide repeat VAPA_1c02380 e0353d74d000a3ab268b51a85d178ec6 850 SUPERFAMILY SSF141571 522 663 3.14E-30 T 12-10-2018 VAPA_1c02380 e0353d74d000a3ab268b51a85d178ec6 850 SUPERFAMILY SSF141571 619 830 5.1E-27 T 12-10-2018 VAPA_1c02380 e0353d74d000a3ab268b51a85d178ec6 850 Pfam PF00805 Pentapeptide repeats (8 copies) 555 592 5.2E-10 T 12-10-2018 IPR001646 Pentapeptide repeat VAPA_1c02380 e0353d74d000a3ab268b51a85d178ec6 850 Pfam PF09937 Uncharacterized protein conserved in bacteria (DUF2169) 21 298 8.2E-78 T 12-10-2018 IPR018683 Domain of unknown function DUF2169 VAPA_1c05930 3ce25f705ecad16f465cdfbd222b72bf 442 TIGRFAM TIGR03349 IV_VI_DotU: type IV/VI secretion system protein, DotU family 56 265 5.0E-71 T 12-10-2018 IPR017732 Type IV / VI secretion system, DotU VAPA_1c05930 3ce25f705ecad16f465cdfbd222b72bf 442 Pfam PF09850 Type VI secretion system protein DotU 57 259 8.3E-67 T 12-10-2018 IPR017732 Type IV / VI secretion system, DotU VAPA_1c05930 3ce25f705ecad16f465cdfbd222b72bf 442 SUPERFAMILY SSF103088 297 428 1.44E-24 T 12-10-2018 IPR036737 OmpA-like domain superfamily VAPA_1c05930 3ce25f705ecad16f465cdfbd222b72bf 442 Pfam PF00691 OmpA family 326 422 4.8E-12 T 12-10-2018 IPR006665 OmpA-like domain VAPA_1c05930 3ce25f705ecad16f465cdfbd222b72bf 442 Gene3D G3DSA:3.30.1330.60 281 433 1.3E-44 T 12-10-2018 IPR036737 OmpA-like domain superfamily VAPA_1c05930 3ce25f705ecad16f465cdfbd222b72bf 442 TIGRFAM TIGR03350 type_VI_ompA: type VI secretion system peptidoglycan-associated domain 293 427 2.3E-46 T 12-10-2018 IPR017733 Type VI secretion system peptidoglycan-associated domain VAPA_1c05930 3ce25f705ecad16f465cdfbd222b72bf 442 Gene3D G3DSA:1.25.40.590 55 210 7.5E-55 T 12-10-2018 IPR038522 Type IV / VI secretion system, DotU superfamily VAPA_1c11260 432e9ebd7cd209b9b2d608427cf90191 463 SMART SM00382 241 367 7.6E-6 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c11260 432e9ebd7cd209b9b2d608427cf90191 463 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 308 322 - T 12-10-2018 IPR001482 Type II/IV secretion system protein VAPA_1c11260 432e9ebd7cd209b9b2d608427cf90191 463 Gene3D G3DSA:3.40.50.300 214 463 3.6E-104 T 12-10-2018 VAPA_1c11260 432e9ebd7cd209b9b2d608427cf90191 463 Gene3D G3DSA:3.30.450.90 77 213 6.3E-51 T 12-10-2018 VAPA_1c11260 432e9ebd7cd209b9b2d608427cf90191 463 SUPERFAMILY SSF52540 90 461 1.35E-100 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c11260 432e9ebd7cd209b9b2d608427cf90191 463 SUPERFAMILY SSF160246 3 66 8.37E-9 T 12-10-2018 IPR037257 General secretory system II, protein E, N-terminal superfamily VAPA_1c11260 432e9ebd7cd209b9b2d608427cf90191 463 Pfam PF00437 Type II/IV secretion system protein 117 380 1.6E-88 T 12-10-2018 IPR001482 Type II/IV secretion system protein VAPA_1c17910 7c710563d14402b887b603a822884d39 368 Gene3D G3DSA:3.90.180.10 6 363 1.4E-148 T 12-10-2018 VAPA_1c17910 7c710563d14402b887b603a822884d39 368 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 61 75 - T 12-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 VAPA_1c17910 7c710563d14402b887b603a822884d39 368 Gene3D G3DSA:3.40.50.720 174 311 1.4E-148 T 12-10-2018 VAPA_1c17910 7c710563d14402b887b603a822884d39 368 SUPERFAMILY SSF51735 160 333 1.55E-46 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c17910 7c710563d14402b887b603a822884d39 368 SUPERFAMILY SSF50129 1 185 1.03E-70 T 12-10-2018 IPR011032 GroES-like superfamily VAPA_1c17910 7c710563d14402b887b603a822884d39 368 Pfam PF00107 Zinc-binding dehydrogenase 197 319 1.3E-25 T 12-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 VAPA_1c17910 7c710563d14402b887b603a822884d39 368 TIGRFAM TIGR02818 adh_III_F_hyde: S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase 2 367 1.8E-190 T 12-10-2018 IPR014183 Alcohol dehydrogenase class III GO:0006069|GO:0008270|GO:0051903|GO:0055114 KEGG: 00010+1.1.1.1|KEGG: 00071+1.1.1.1|KEGG: 00260+1.1.1.1|KEGG: 00350+1.1.1.1|KEGG: 00592+1.1.1.1|KEGG: 00625+1.1.1.1|KEGG: 00626+1.1.1.1|KEGG: 00680+1.1.1.284|KEGG: 00830+1.1.1.1|KEGG: 00980+1.1.1.1|KEGG: 00982+1.1.1.1|MetaCyc: PWY-1801|MetaCyc: PWY-3162|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5079|MetaCyc: PWY-5082|MetaCyc: PWY-5480|MetaCyc: PWY-5486|MetaCyc: PWY-5751|MetaCyc: PWY-6313|MetaCyc: PWY-6333|MetaCyc: PWY-6342|MetaCyc: PWY-6587|MetaCyc: PWY-6802|MetaCyc: PWY-6871|MetaCyc: PWY-7013|MetaCyc: PWY-7111|MetaCyc: PWY-7118|MetaCyc: PWY-7396|MetaCyc: PWY-7798|Reactome: R-HSA-71384 VAPA_1c17910 7c710563d14402b887b603a822884d39 368 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 153 1.9E-24 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 VAPA_1c17910 7c710563d14402b887b603a822884d39 368 SUPERFAMILY SSF50129 318 368 1.13E-12 T 12-10-2018 IPR011032 GroES-like superfamily VAPA_1c17910 7c710563d14402b887b603a822884d39 368 SMART SM00829 12 367 7.4E-4 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 VAPA_2c04630 8f98a12506251a184b523a3fa10ccf6e 239 Pfam PF00005 ABC transporter 29 172 1.1E-31 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_2c04630 8f98a12506251a184b523a3fa10ccf6e 239 SMART SM00382 38 221 7.6E-15 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_2c04630 8f98a12506251a184b523a3fa10ccf6e 239 Gene3D G3DSA:3.40.50.300 8 236 3.3E-63 T 12-10-2018 VAPA_2c04630 8f98a12506251a184b523a3fa10ccf6e 239 SUPERFAMILY SSF52540 10 228 4.11E-66 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_2c04630 8f98a12506251a184b523a3fa10ccf6e 239 ProSitePatterns PS00211 ABC transporters family signature. 145 159 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_1c14190 d95e53c3608b7dcbbddcf13b2d84f35e 196 Pfam PF03358 NADPH-dependent FMN reductase 4 147 1.7E-25 T 12-10-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 VAPA_1c14190 d95e53c3608b7dcbbddcf13b2d84f35e 196 SUPERFAMILY SSF52218 4 160 1.54E-32 T 12-10-2018 IPR029039 Flavoprotein-like superfamily VAPA_1c14190 d95e53c3608b7dcbbddcf13b2d84f35e 196 Gene3D G3DSA:3.40.50.360 3 194 3.1E-38 T 12-10-2018 IPR029039 Flavoprotein-like superfamily VAPA_2c03350 7d87c6233e33de171da0b95237ae2a95 900 SUPERFAMILY SSF52210 127 293 2.75E-47 T 12-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 VAPA_2c03350 7d87c6233e33de171da0b95237ae2a95 900 SMART SM00881 9 104 1.7E-28 T 12-10-2018 IPR003781 CoA-binding GO:0048037 VAPA_2c03350 7d87c6233e33de171da0b95237ae2a95 900 SUPERFAMILY SSF55729 725 869 1.29E-19 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase VAPA_2c03350 7d87c6233e33de171da0b95237ae2a95 900 SUPERFAMILY SSF51735 3 137 2.88E-33 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_2c03350 7d87c6233e33de171da0b95237ae2a95 900 Pfam PF13380 CoA binding domain 14 132 9.3E-25 T 12-10-2018 IPR003781 CoA-binding GO:0048037 VAPA_2c03350 7d87c6233e33de171da0b95237ae2a95 900 Gene3D G3DSA:3.40.50.720 3 127 1.9E-35 T 12-10-2018 VAPA_2c03350 7d87c6233e33de171da0b95237ae2a95 900 Gene3D G3DSA:3.30.1490.20 501 579 1.5E-79 T 12-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 VAPA_2c03350 7d87c6233e33de171da0b95237ae2a95 900 Gene3D G3DSA:3.30.470.20 483 695 1.5E-79 T 12-10-2018 VAPA_2c03350 7d87c6233e33de171da0b95237ae2a95 900 Pfam PF13549 ATP-grasp domain 475 697 2.0E-85 T 12-10-2018 VAPA_2c03350 7d87c6233e33de171da0b95237ae2a95 900 Pfam PF00583 Acetyltransferase (GNAT) family 770 866 2.2E-7 T 12-10-2018 IPR000182 GNAT domain VAPA_2c03350 7d87c6233e33de171da0b95237ae2a95 900 Gene3D G3DSA:3.40.50.261 128 288 1.2E-60 T 12-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 VAPA_2c03350 7d87c6233e33de171da0b95237ae2a95 900 Gene3D G3DSA:3.40.630.30 721 887 2.6E-38 T 12-10-2018 VAPA_2c03350 7d87c6233e33de171da0b95237ae2a95 900 Gene3D G3DSA:3.40.50.261 291 456 1.4E-43 T 12-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 VAPA_2c03350 7d87c6233e33de171da0b95237ae2a95 900 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 149 286 9.6E-59 T 12-10-2018 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain VAPA_2c03350 7d87c6233e33de171da0b95237ae2a95 900 SUPERFAMILY SSF52210 296 449 5.1E-35 T 12-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 VAPA_2c03350 7d87c6233e33de171da0b95237ae2a95 900 SUPERFAMILY SSF56059 482 698 7.95E-43 T 12-10-2018 VAPA_1c42840 d03f072c8678b8cc0b9490a9bde5e418 243 ProSitePatterns PS01183 ubiE/COQ5 methyltransferase family signature 1. 31 46 - T 12-10-2018 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 VAPA_1c42840 d03f072c8678b8cc0b9490a9bde5e418 243 Hamap MF_01813 Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE [ubiE]. 11 242 36.956 T 12-10-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 VAPA_1c42840 d03f072c8678b8cc0b9490a9bde5e418 243 Pfam PF01209 ubiE/COQ5 methyltransferase family 15 242 1.3E-86 T 12-10-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 VAPA_1c42840 d03f072c8678b8cc0b9490a9bde5e418 243 SUPERFAMILY SSF53335 8 237 2.05E-45 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase VAPA_1c42840 d03f072c8678b8cc0b9490a9bde5e418 243 Gene3D G3DSA:3.40.50.150 26 243 2.2E-69 T 12-10-2018 VAPA_1c42840 d03f072c8678b8cc0b9490a9bde5e418 243 TIGRFAM TIGR01934 MenG_MenH_UbiE: ubiquinone/menaquinone biosynthesis methyltransferase 20 242 2.2E-79 T 12-10-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 VAPA_1c18030 d0e82adf1e2c26f9ff35abb7d15acb9b 116 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 20 113 5.5E-35 T 12-10-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain VAPA_1c18030 d0e82adf1e2c26f9ff35abb7d15acb9b 116 Gene3D G3DSA:3.10.50.40 1 116 2.7E-49 T 12-10-2018 VAPA_1c18030 d0e82adf1e2c26f9ff35abb7d15acb9b 116 SUPERFAMILY SSF54534 2 114 1.16E-43 T 12-10-2018 VAPA_1c23140 c4a7e8190e713ee80236b793e4465cd3 107 Pfam PF01521 Iron-sulphur cluster biosynthesis 1 103 2.8E-21 T 12-10-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 VAPA_1c23140 c4a7e8190e713ee80236b793e4465cd3 107 Gene3D G3DSA:2.60.300.12 2 107 9.5E-36 T 12-10-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 VAPA_1c23140 c4a7e8190e713ee80236b793e4465cd3 107 TIGRFAM TIGR00049 TIGR00049: iron-sulfur cluster assembly accessory protein 3 106 2.9E-35 T 12-10-2018 IPR016092 FeS cluster insertion protein GO:0005198|GO:0051536|GO:0097428 Reactome: R-HSA-1362409 VAPA_1c23140 c4a7e8190e713ee80236b793e4465cd3 107 SUPERFAMILY SSF89360 1 95 2.22E-31 T 12-10-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 VAPA_1c23140 c4a7e8190e713ee80236b793e4465cd3 107 ProSitePatterns PS01152 Hypothetical hesB/yadR/yfhF family signature. 88 105 - T 12-10-2018 IPR017870 FeS cluster insertion, C-terminal, conserved site Reactome: R-HSA-1362409 VAPA_1c23140 c4a7e8190e713ee80236b793e4465cd3 107 TIGRFAM TIGR02011 IscA: iron-sulfur cluster assembly protein IscA 3 107 1.3E-52 T 12-10-2018 IPR011302 Iron-binding protein IscA, proteobacteria GO:0005506|GO:0051536|GO:0097428 VAPA_1c11590 0a1829fedbed287c897ebb330b41090e 520 Gene3D G3DSA:3.40.50.10490 99 281 5.7E-192 T 12-10-2018 VAPA_1c11590 0a1829fedbed287c897ebb330b41090e 520 SUPERFAMILY SSF53697 9 515 7.79E-181 T 12-10-2018 VAPA_1c11590 0a1829fedbed287c897ebb330b41090e 520 Hamap MF_00473 Glucose-6-phosphate isomerase [pgi]. 47 497 38.628 T 12-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 VAPA_1c11590 0a1829fedbed287c897ebb330b41090e 520 ProSitePatterns PS00174 Phosphoglucose isomerase signature 2. 470 487 - T 12-10-2018 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 VAPA_1c11590 0a1829fedbed287c897ebb330b41090e 520 Gene3D G3DSA:3.40.50.10490 13 479 5.7E-192 T 12-10-2018 VAPA_1c11590 0a1829fedbed287c897ebb330b41090e 520 ProSitePatterns PS00765 Phosphoglucose isomerase signature 1. 255 268 - T 12-10-2018 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 VAPA_1c11590 0a1829fedbed287c897ebb330b41090e 520 Pfam PF00342 Phosphoglucose isomerase 53 513 5.0E-174 T 12-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 VAPA_1c11590 0a1829fedbed287c897ebb330b41090e 520 PRINTS PR00662 Glucose-6-phosphate isomerase signature 438 456 1.4E-51 T 12-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 VAPA_1c11590 0a1829fedbed287c897ebb330b41090e 520 PRINTS PR00662 Glucose-6-phosphate isomerase signature 456 470 1.4E-51 T 12-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 VAPA_1c11590 0a1829fedbed287c897ebb330b41090e 520 PRINTS PR00662 Glucose-6-phosphate isomerase signature 328 349 1.4E-51 T 12-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 VAPA_1c11590 0a1829fedbed287c897ebb330b41090e 520 PRINTS PR00662 Glucose-6-phosphate isomerase signature 143 162 1.4E-51 T 12-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 VAPA_1c11590 0a1829fedbed287c897ebb330b41090e 520 PRINTS PR00662 Glucose-6-phosphate isomerase signature 251 269 1.4E-51 T 12-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 VAPA_1c11590 0a1829fedbed287c897ebb330b41090e 520 PRINTS PR00662 Glucose-6-phosphate isomerase signature 470 483 1.4E-51 T 12-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 VAPA_1c11590 0a1829fedbed287c897ebb330b41090e 520 Gene3D G3DSA:1.10.1390.10 480 518 8.9E-18 T 12-10-2018 IPR023096 Phosphoglucose isomerase, C-terminal GO:0004347|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 VAPA_2c07210 755db482be098bb26604158ccf0a6e98 404 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 44 379 3.4E-84 T 12-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 VAPA_2c07210 755db482be098bb26604158ccf0a6e98 404 Gene3D G3DSA:2.40.420.20 308 377 7.4E-105 T 12-10-2018 VAPA_2c07210 755db482be098bb26604158ccf0a6e98 404 Gene3D G3DSA:2.40.50.100 68 212 7.4E-105 T 12-10-2018 VAPA_2c07210 755db482be098bb26604158ccf0a6e98 404 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 69 297 2.3E-11 T 12-10-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain VAPA_2c07210 755db482be098bb26604158ccf0a6e98 404 Gene3D G3DSA:1.10.287.470 103 176 7.4E-105 T 12-10-2018 VAPA_2c07210 755db482be098bb26604158ccf0a6e98 404 Pfam PF00529 HlyD membrane-fusion protein of T1SS 305 365 2.0E-9 T 12-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 VAPA_2c07210 755db482be098bb26604158ccf0a6e98 404 Gene3D G3DSA:2.40.30.170 57 307 7.4E-105 T 12-10-2018 VAPA_2c07210 755db482be098bb26604158ccf0a6e98 404 SUPERFAMILY SSF111369 57 302 2.88E-78 T 12-10-2018 VAPA_1c10310 99f088618a5a21f528f2c4b0af159d87 371 Pfam PF02636 Putative S-adenosyl-L-methionine-dependent methyltransferase 78 306 2.6E-42 T 12-10-2018 IPR003788 Protein arginine methyltransferase NDUFAF7 Reactome: R-HSA-6799198 VAPA_1c10310 99f088618a5a21f528f2c4b0af159d87 371 Gene3D G3DSA:3.40.50.12710 4 371 1.0E-117 T 12-10-2018 IPR038375 Protein arginine methyltransferase NDUFAF7 superfamily Reactome: R-HSA-6799198 VAPA_1c10310 99f088618a5a21f528f2c4b0af159d87 371 SUPERFAMILY SSF53335 20 362 1.98E-86 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase VAPA_1c03310 ea65e6d656a2c60dc5d2d91a73d98205 307 Pfam PF02653 Branched-chain amino acid transport system / permease component 17 287 2.4E-31 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 VAPA_1c54690 286358694000ab47f6ae238788d8cf49 703 SUPERFAMILY SSF52518 343 562 1.77E-60 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold VAPA_1c54690 286358694000ab47f6ae238788d8cf49 703 SUPERFAMILY SSF52518 7 331 1.37E-116 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold VAPA_1c54690 286358694000ab47f6ae238788d8cf49 703 Gene3D G3DSA:3.40.50.970 2 326 1.3E-132 T 12-10-2018 VAPA_1c54690 286358694000ab47f6ae238788d8cf49 703 Gene3D G3DSA:3.40.50.920 574 703 2.7E-42 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 VAPA_1c54690 286358694000ab47f6ae238788d8cf49 703 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 5 334 3.6E-153 T 12-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 VAPA_1c54690 286358694000ab47f6ae238788d8cf49 703 Pfam PF02780 Transketolase, C-terminal domain 587 693 4.8E-13 T 12-10-2018 IPR033248 Transketolase, C-terminal domain VAPA_1c54690 286358694000ab47f6ae238788d8cf49 703 SMART SM00861 355 562 2.2E-57 T 12-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain VAPA_1c54690 286358694000ab47f6ae238788d8cf49 703 Pfam PF02779 Transketolase, pyrimidine binding domain 354 560 2.1E-44 T 12-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain VAPA_1c54690 286358694000ab47f6ae238788d8cf49 703 ProSitePatterns PS00801 Transketolase signature 1. 12 32 - T 12-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 VAPA_1c54690 286358694000ab47f6ae238788d8cf49 703 SUPERFAMILY SSF52922 568 701 2.36E-39 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 VAPA_1c07430 095a4adfa6015752eba2d9efd2e163a0 1409 Hamap MF_01322 DNA-directed RNA polymerase subunit beta' [rpoC]. 10 1375 18.507 T 12-10-2018 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 VAPA_1c07430 095a4adfa6015752eba2d9efd2e163a0 1409 Pfam PF04997 RNA polymerase Rpb1, domain 1 16 340 3.8E-81 T 12-10-2018 IPR007080 RNA polymerase Rpb1, domain 1 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 VAPA_1c07430 095a4adfa6015752eba2d9efd2e163a0 1409 Pfam PF04983 RNA polymerase Rpb1, domain 3 487 643 1.1E-23 T 12-10-2018 IPR007066 RNA polymerase Rpb1, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 VAPA_1c07430 095a4adfa6015752eba2d9efd2e163a0 1409 TIGRFAM TIGR02386 rpoC_TIGR: DNA-directed RNA polymerase, beta' subunit 19 1365 0.0 T 12-10-2018 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 VAPA_1c07430 095a4adfa6015752eba2d9efd2e163a0 1409 Gene3D G3DSA:1.10.132.30 640 789 2.6E-64 T 12-10-2018 IPR038120 RNA polymerase Rpb1, funnel domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 VAPA_1c07430 095a4adfa6015752eba2d9efd2e163a0 1409 SMART SM00663 233 512 2.1E-169 T 12-10-2018 IPR006592 RNA polymerase, N-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 VAPA_1c07430 095a4adfa6015752eba2d9efd2e163a0 1409 Pfam PF00623 RNA polymerase Rpb1, domain 2 342 393 8.1E-8 T 12-10-2018 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 VAPA_1c07430 095a4adfa6015752eba2d9efd2e163a0 1409 Pfam PF00623 RNA polymerase Rpb1, domain 2 390 483 4.5E-27 T 12-10-2018 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 VAPA_1c07430 095a4adfa6015752eba2d9efd2e163a0 1409 Gene3D G3DSA:2.40.50.100 1023 1125 2.6E-26 T 12-10-2018 VAPA_1c07430 095a4adfa6015752eba2d9efd2e163a0 1409 Gene3D G3DSA:1.10.150.390 1314 1375 5.6E-29 T 12-10-2018 VAPA_1c07430 095a4adfa6015752eba2d9efd2e163a0 1409 Gene3D G3DSA:1.10.1790.20 1134 1312 2.4E-62 T 12-10-2018 VAPA_1c07430 095a4adfa6015752eba2d9efd2e163a0 1409 Gene3D G3DSA:2.40.50.100 1150 1213 2.4E-62 T 12-10-2018 VAPA_1c07430 095a4adfa6015752eba2d9efd2e163a0 1409 Gene3D G3DSA:1.10.40.90 372 414 4.9E-19 T 12-10-2018 VAPA_1c07430 095a4adfa6015752eba2d9efd2e163a0 1409 Pfam PF04998 RNA polymerase Rpb1, domain 5 765 1314 1.3E-73 T 12-10-2018 IPR007081 RNA polymerase Rpb1, domain 5 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 VAPA_1c07430 095a4adfa6015752eba2d9efd2e163a0 1409 Gene3D G3DSA:2.40.50.100 947 1022 2.4E-27 T 12-10-2018 VAPA_1c07430 095a4adfa6015752eba2d9efd2e163a0 1409 Pfam PF05000 RNA polymerase Rpb1, domain 4 673 762 7.0E-19 T 12-10-2018 IPR007083 RNA polymerase Rpb1, domain 4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 VAPA_1c07430 095a4adfa6015752eba2d9efd2e163a0 1409 Gene3D G3DSA:1.10.274.100 488 639 4.6E-35 T 12-10-2018 VAPA_1c07430 095a4adfa6015752eba2d9efd2e163a0 1409 SUPERFAMILY SSF64484 17 1362 0.0 T 12-10-2018 VAPA_1c32000 f4ba39f1e96c4fc6f981aa62d4f5d0dd 247 Hamap MF_01057 tRNA (guanine-N(7)-)-methyltransferase [trmB]. 34 247 28.761 T 12-10-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 VAPA_1c32000 f4ba39f1e96c4fc6f981aa62d4f5d0dd 247 Gene3D G3DSA:3.40.50.150 40 247 2.9E-64 T 12-10-2018 VAPA_1c32000 f4ba39f1e96c4fc6f981aa62d4f5d0dd 247 TIGRFAM TIGR00091 TIGR00091: tRNA (guanine-N(7)-)-methyltransferase 64 246 7.4E-52 T 12-10-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 VAPA_1c32000 f4ba39f1e96c4fc6f981aa62d4f5d0dd 247 SUPERFAMILY SSF53335 28 246 9.14E-43 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase VAPA_1c32000 f4ba39f1e96c4fc6f981aa62d4f5d0dd 247 Pfam PF02390 Putative methyltransferase 76 242 3.9E-54 T 12-10-2018 VAPA_1c28450 ea1777983ae1d2434ec45dc57e9b7396 391 Pfam PF07687 Peptidase dimerisation domain 183 294 2.0E-21 T 12-10-2018 IPR011650 Peptidase M20, dimerisation domain VAPA_1c28450 ea1777983ae1d2434ec45dc57e9b7396 391 Hamap MF_01690 Succinyl-diaminopimelate desuccinylase [dapE]. 2 387 49.19 T 12-10-2018 IPR005941 Succinyl-diaminopimelate desuccinylase, proteobacteria GO:0009014|GO:0009089 KEGG: 00300+3.5.1.18 VAPA_1c28450 ea1777983ae1d2434ec45dc57e9b7396 391 SUPERFAMILY SSF53187 2 385 2.88E-62 T 12-10-2018 VAPA_1c28450 ea1777983ae1d2434ec45dc57e9b7396 391 Gene3D G3DSA:3.30.70.360 187 304 1.5E-120 T 12-10-2018 VAPA_1c28450 ea1777983ae1d2434ec45dc57e9b7396 391 SUPERFAMILY SSF55031 187 300 1.12E-26 T 12-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain VAPA_1c28450 ea1777983ae1d2434ec45dc57e9b7396 391 Gene3D G3DSA:3.40.630.10 7 374 1.5E-120 T 12-10-2018 VAPA_1c28450 ea1777983ae1d2434ec45dc57e9b7396 391 Pfam PF01546 Peptidase family M20/M25/M40 71 383 1.3E-41 T 12-10-2018 IPR002933 Peptidase M20 GO:0016787 VAPA_1c28450 ea1777983ae1d2434ec45dc57e9b7396 391 TIGRFAM TIGR01246 dapE_proteo: succinyl-diaminopimelate desuccinylase 5 385 3.8E-149 T 12-10-2018 IPR005941 Succinyl-diaminopimelate desuccinylase, proteobacteria GO:0009014|GO:0009089 KEGG: 00300+3.5.1.18 VAPA_2c12160 7f2b9fbe7320644af80421843b92810a 46 Gene3D G3DSA:1.10.357.10 1 46 1.5E-6 T 12-10-2018 VAPA_2c12160 7f2b9fbe7320644af80421843b92810a 46 Pfam PF14246 AefR-like transcriptional repressor, C-terminal region 2 41 1.2E-8 T 12-10-2018 IPR039536 Transcriptional regulator TetR, C-terminal, Proteobacteria type VAPA_2c05350 c6b80486ce90aed31b8176a5a177ff78 220 ProDom PD037531 MEMBRANE HYDROGENASE SUBUNIT COMPONENT HYDROGENASE-4 E OXIDOREDUCTASE PRECURSOR SIGNAL 1.-.-.- 16 181 2.0E-66 T 12-10-2018 VAPA_2c07860 c323fe33808ace9147ec1df00aad1c19 408 Pfam PF07995 Glucose / Sorbosone dehydrogenase 59 400 1.7E-123 T 12-10-2018 IPR012938 Glucose/Sorbosone dehydrogenase VAPA_2c07860 c323fe33808ace9147ec1df00aad1c19 408 SUPERFAMILY SSF50952 49 402 1.96E-46 T 12-10-2018 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 VAPA_2c07860 c323fe33808ace9147ec1df00aad1c19 408 Gene3D G3DSA:2.120.10.30 44 403 1.7E-114 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like VAPA_1c12800 008389c00eaf4753b52158e989b0f26a 303 Pfam PF01418 Helix-turn-helix domain, rpiR family 5 77 1.0E-15 T 12-10-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 VAPA_1c12800 008389c00eaf4753b52158e989b0f26a 303 SUPERFAMILY SSF46689 1 76 1.13E-14 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 VAPA_1c12800 008389c00eaf4753b52158e989b0f26a 303 Gene3D G3DSA:3.40.50.10490 92 281 3.8E-30 T 12-10-2018 VAPA_1c12800 008389c00eaf4753b52158e989b0f26a 303 SUPERFAMILY SSF53697 95 265 1.09E-26 T 12-10-2018 VAPA_1c12800 008389c00eaf4753b52158e989b0f26a 303 Gene3D G3DSA:1.10.10.10 1 79 1.7E-18 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c12800 008389c00eaf4753b52158e989b0f26a 303 Pfam PF01380 SIS domain 127 255 4.3E-7 T 12-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 VAPA_1c54360 fada7187ddf5d5a518be5448ca27f01e 342 SUPERFAMILY SSF52768 2 338 1.25E-84 T 12-10-2018 IPR023696 Ureohydrolase domain superfamily VAPA_1c54360 fada7187ddf5d5a518be5448ca27f01e 342 Pfam PF00850 Histone deacetylase domain 29 335 1.0E-64 T 12-10-2018 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 VAPA_1c54360 fada7187ddf5d5a518be5448ca27f01e 342 PRINTS PR01270 Histone deacetylase superfamily signature 155 178 2.1E-16 T 12-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 VAPA_1c54360 fada7187ddf5d5a518be5448ca27f01e 342 PRINTS PR01270 Histone deacetylase superfamily signature 273 283 2.1E-16 T 12-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 VAPA_1c54360 fada7187ddf5d5a518be5448ca27f01e 342 PRINTS PR01270 Histone deacetylase superfamily signature 187 202 2.1E-16 T 12-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 VAPA_1c54360 fada7187ddf5d5a518be5448ca27f01e 342 Gene3D G3DSA:3.40.800.20 1 342 9.6E-114 T 12-10-2018 IPR037138 Histone deacetylase domain superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 VAPA_1c23380 a886919449b488193735c19ed21e63ab 210 Pfam PF00196 Bacterial regulatory proteins, luxR family 145 199 1.7E-19 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_1c23380 a886919449b488193735c19ed21e63ab 210 SUPERFAMILY SSF52172 7 131 2.7E-33 T 12-10-2018 IPR011006 CheY-like superfamily VAPA_1c23380 a886919449b488193735c19ed21e63ab 210 Gene3D G3DSA:1.10.10.10 139 203 3.3E-20 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c23380 a886919449b488193735c19ed21e63ab 210 Pfam PF00072 Response regulator receiver domain 10 119 6.0E-27 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_1c23380 a886919449b488193735c19ed21e63ab 210 Gene3D G3DSA:3.40.50.2300 3 136 8.2E-50 T 12-10-2018 VAPA_1c23380 a886919449b488193735c19ed21e63ab 210 SMART SM00448 8 119 7.8E-27 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_1c23380 a886919449b488193735c19ed21e63ab 210 SUPERFAMILY SSF46894 135 201 6.12E-19 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 VAPA_1c23380 a886919449b488193735c19ed21e63ab 210 ProSitePatterns PS00622 LuxR-type HTH domain signature. 160 187 - T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_1c23380 a886919449b488193735c19ed21e63ab 210 SMART SM00421 143 200 2.1E-19 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_1c23380 a886919449b488193735c19ed21e63ab 210 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 176 188 5.3E-13 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_1c23380 a886919449b488193735c19ed21e63ab 210 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 160 176 5.3E-13 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_1c23380 a886919449b488193735c19ed21e63ab 210 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 146 160 5.3E-13 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_1c26470 1b5ce1054164a501936ce514fc72e23e 325 PIRSF PIRSF017082 1 322 1.1E-65 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c26470 1b5ce1054164a501936ce514fc72e23e 325 Gene3D G3DSA:3.40.190.10 126 249 6.0E-99 T 12-10-2018 VAPA_1c26470 1b5ce1054164a501936ce514fc72e23e 325 Gene3D G3DSA:3.40.190.150 28 314 6.0E-99 T 12-10-2018 VAPA_1c26470 1b5ce1054164a501936ce514fc72e23e 325 SUPERFAMILY SSF53850 115 292 7.6E-7 T 12-10-2018 VAPA_1c26470 1b5ce1054164a501936ce514fc72e23e 325 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 47 318 1.6E-69 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_2c09660 9ce388516c7835f9d55b0e47a44af424 414 Pfam PF00355 Rieske [2Fe-2S] domain 44 125 1.6E-18 T 12-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 VAPA_2c09660 9ce388516c7835f9d55b0e47a44af424 414 SUPERFAMILY SSF50022 11 163 9.17E-40 T 12-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 VAPA_2c09660 9ce388516c7835f9d55b0e47a44af424 414 ProSitePatterns PS00570 Bacterial ring hydroxylating dioxygenases alpha-subunit signature. 86 109 - T 12-10-2018 IPR015881 Aromatic-ring-hydroxylating dioxygenase, 2Fe-2S-binding site GO:0005506|GO:0051537|GO:0055114 VAPA_2c09660 9ce388516c7835f9d55b0e47a44af424 414 Gene3D G3DSA:2.102.10.10 43 172 3.1E-79 T 12-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 VAPA_2c09660 9ce388516c7835f9d55b0e47a44af424 414 Gene3D G3DSA:3.90.380.10 20 412 3.1E-79 T 12-10-2018 VAPA_2c09660 9ce388516c7835f9d55b0e47a44af424 414 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 79 99 1.6E-27 T 12-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 VAPA_2c09660 9ce388516c7835f9d55b0e47a44af424 414 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 58 73 1.6E-27 T 12-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 VAPA_2c09660 9ce388516c7835f9d55b0e47a44af424 414 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 148 174 1.6E-27 T 12-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 VAPA_2c09660 9ce388516c7835f9d55b0e47a44af424 414 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 186 208 1.6E-27 T 12-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 VAPA_2c09660 9ce388516c7835f9d55b0e47a44af424 414 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 100 120 1.6E-27 T 12-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 VAPA_2c09660 9ce388516c7835f9d55b0e47a44af424 414 SUPERFAMILY SSF55961 164 414 1.49E-42 T 12-10-2018 VAPA_2c09660 9ce388516c7835f9d55b0e47a44af424 414 Pfam PF00848 Ring hydroxylating alpha subunit (catalytic domain) 194 413 6.7E-16 T 12-10-2018 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0044237|GO:0051537|GO:0055114 VAPA_2c05820 226f4a915fa6b2ad9f0a93a181752cc0 307 Pfam PF03466 LysR substrate binding domain 94 294 7.2E-49 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_2c05820 226f4a915fa6b2ad9f0a93a181752cc0 307 Gene3D G3DSA:1.10.10.10 5 96 1.2E-25 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_2c05820 226f4a915fa6b2ad9f0a93a181752cc0 307 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 43 54 6.4E-10 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_2c05820 226f4a915fa6b2ad9f0a93a181752cc0 307 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 22 33 6.4E-10 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_2c05820 226f4a915fa6b2ad9f0a93a181752cc0 307 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 33 43 6.4E-10 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_2c05820 226f4a915fa6b2ad9f0a93a181752cc0 307 SUPERFAMILY SSF46785 6 87 2.39E-23 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_2c05820 226f4a915fa6b2ad9f0a93a181752cc0 307 SUPERFAMILY SSF53850 95 298 8.6E-48 T 12-10-2018 VAPA_2c05820 226f4a915fa6b2ad9f0a93a181752cc0 307 Gene3D G3DSA:3.40.190.290 97 305 4.7E-53 T 12-10-2018 VAPA_2c05820 226f4a915fa6b2ad9f0a93a181752cc0 307 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 66 2.9E-22 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c16830 f176be6f771d65357152d4f0d133f043 252 Gene3D G3DSA:1.10.3720.10 2 234 2.9E-27 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c16830 f176be6f771d65357152d4f0d133f043 252 SUPERFAMILY SSF161098 12 222 3.53E-30 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c16830 f176be6f771d65357152d4f0d133f043 252 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 44 225 4.3E-7 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 VAPA_2c07650 3d8eb207fed24ed99c079ccca3186831 293 Gene3D G3DSA:3.40.190.10 88 287 1.3E-50 T 12-10-2018 VAPA_2c07650 3d8eb207fed24ed99c079ccca3186831 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 7.9E-10 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_2c07650 3d8eb207fed24ed99c079ccca3186831 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 7.9E-10 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_2c07650 3d8eb207fed24ed99c079ccca3186831 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 7.9E-10 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_2c07650 3d8eb207fed24ed99c079ccca3186831 293 Gene3D G3DSA:3.40.190.10 163 270 1.3E-50 T 12-10-2018 VAPA_2c07650 3d8eb207fed24ed99c079ccca3186831 293 Pfam PF03466 LysR substrate binding domain 87 291 6.1E-38 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_2c07650 3d8eb207fed24ed99c079ccca3186831 293 SUPERFAMILY SSF46785 1 111 1.47E-23 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_2c07650 3d8eb207fed24ed99c079ccca3186831 293 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 61 1.4E-21 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_2c07650 3d8eb207fed24ed99c079ccca3186831 293 Gene3D G3DSA:1.10.10.10 1 86 1.5E-24 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_2c07650 3d8eb207fed24ed99c079ccca3186831 293 SUPERFAMILY SSF53850 89 291 2.68E-35 T 12-10-2018 VAPA_1c54020 de580a5e48d4dd19619053b3a2d5e6e9 150 Pfam PF02631 RecX family 30 145 6.6E-24 T 12-10-2018 IPR003783 Regulatory protein RecX GO:0006282 VAPA_1c54020 de580a5e48d4dd19619053b3a2d5e6e9 150 Hamap MF_01114 Regulatory protein RecX [recX]. 4 150 12.773 T 12-10-2018 IPR003783 Regulatory protein RecX GO:0006282 VAPA_1c54020 de580a5e48d4dd19619053b3a2d5e6e9 150 Gene3D G3DSA:1.10.10.10 101 146 8.1E-12 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c54020 de580a5e48d4dd19619053b3a2d5e6e9 150 Gene3D G3DSA:1.10.10.10 9 52 1.8E-8 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c54020 de580a5e48d4dd19619053b3a2d5e6e9 150 Gene3D G3DSA:1.10.10.10 56 96 7.8E-7 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c36390 9bca230e02438e95e91550b090ac49ab 931 Gene3D G3DSA:3.40.50.740 69 543 5.4E-195 T 12-10-2018 VAPA_1c36390 9bca230e02438e95e91550b090ac49ab 931 Pfam PF00384 Molybdopterin oxidoreductase 62 490 2.4E-82 T 12-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VAPA_1c36390 9bca230e02438e95e91550b090ac49ab 931 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 1 50 9.7E-19 T 12-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VAPA_1c36390 9bca230e02438e95e91550b090ac49ab 931 Pfam PF04324 BFD-like [2Fe-2S] binding domain 868 919 1.8E-5 T 12-10-2018 IPR007419 BFD-like [2Fe-2S]-binding domain VAPA_1c36390 9bca230e02438e95e91550b090ac49ab 931 Gene3D G3DSA:1.10.10.1100 868 926 6.2E-6 T 12-10-2018 VAPA_1c36390 9bca230e02438e95e91550b090ac49ab 931 SMART SM00926 1 55 7.3E-22 T 12-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VAPA_1c36390 9bca230e02438e95e91550b090ac49ab 931 SUPERFAMILY SSF50692 561 713 1.15E-39 T 12-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily VAPA_1c36390 9bca230e02438e95e91550b090ac49ab 931 Pfam PF01568 Molydopterin dinucleotide binding domain 588 707 1.1E-23 T 12-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 VAPA_1c36390 9bca230e02438e95e91550b090ac49ab 931 PIRSF PIRSF036643 1 722 1.1E-164 T 12-10-2018 VAPA_1c36390 9bca230e02438e95e91550b090ac49ab 931 Gene3D G3DSA:2.20.25.90 1 53 1.6E-17 T 12-10-2018 VAPA_1c36390 9bca230e02438e95e91550b090ac49ab 931 ProSitePatterns PS00490 Prokaryotic molybdopterin oxidoreductases signature 2. 436 453 - T 12-10-2018 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 VAPA_1c36390 9bca230e02438e95e91550b090ac49ab 931 SUPERFAMILY SSF53706 1 589 3.14E-198 T 12-10-2018 VAPA_1c36390 9bca230e02438e95e91550b090ac49ab 931 Gene3D G3DSA:2.40.40.20 578 713 8.0E-38 T 12-10-2018 VAPA_1c36390 9bca230e02438e95e91550b090ac49ab 931 Gene3D G3DSA:3.40.228.10 142 343 5.4E-195 T 12-10-2018 VAPA_2c01180 abdec905c04592d63351f6b3bc3a0ad3 393 Pfam PF02515 CoA-transferase family III 17 369 2.3E-100 T 12-10-2018 IPR003673 CoA-transferase family III GO:0003824 VAPA_2c01180 abdec905c04592d63351f6b3bc3a0ad3 393 Gene3D G3DSA:3.30.1540.10 228 317 3.2E-111 T 12-10-2018 VAPA_2c01180 abdec905c04592d63351f6b3bc3a0ad3 393 SUPERFAMILY SSF89796 15 392 2.22E-117 T 12-10-2018 IPR023606 CoA-transferase family III domain superfamily VAPA_2c01180 abdec905c04592d63351f6b3bc3a0ad3 393 Gene3D G3DSA:3.40.50.10540 16 334 3.2E-111 T 12-10-2018 IPR023606 CoA-transferase family III domain superfamily VAPA_2c02980 098b3bad8ea23da10a84c27c1a7a4f29 249 Pfam PF07702 UTRA domain 102 241 1.8E-18 T 12-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 VAPA_2c02980 098b3bad8ea23da10a84c27c1a7a4f29 249 Pfam PF00392 Bacterial regulatory proteins, gntR family 16 76 6.1E-18 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_2c02980 098b3bad8ea23da10a84c27c1a7a4f29 249 SUPERFAMILY SSF64288 64 249 1.21E-28 T 12-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily VAPA_2c02980 098b3bad8ea23da10a84c27c1a7a4f29 249 SUPERFAMILY SSF46785 13 80 3.71E-19 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_2c02980 098b3bad8ea23da10a84c27c1a7a4f29 249 SMART SM00866 97 242 1.1E-19 T 12-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 VAPA_2c02980 098b3bad8ea23da10a84c27c1a7a4f29 249 Gene3D G3DSA:1.10.10.10 8 81 2.5E-20 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_2c02980 098b3bad8ea23da10a84c27c1a7a4f29 249 SMART SM00345 17 76 6.4E-15 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_2c02980 098b3bad8ea23da10a84c27c1a7a4f29 249 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 50 66 4.9E-8 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_2c02980 098b3bad8ea23da10a84c27c1a7a4f29 249 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 36 50 4.9E-8 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_2c02980 098b3bad8ea23da10a84c27c1a7a4f29 249 Gene3D G3DSA:3.40.1410.10 91 249 1.6E-27 T 12-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily VAPA_1c48030 7f34222e02b61b6bcfb42e0dd3635eca 589 Pfam PF12146 Serine aminopeptidase, S33 36 271 3.9E-66 T 12-10-2018 IPR022742 Serine aminopeptidase, S33 VAPA_1c48030 7f34222e02b61b6bcfb42e0dd3635eca 589 Gene3D G3DSA:3.40.50.150 349 587 1.1E-15 T 12-10-2018 VAPA_1c48030 7f34222e02b61b6bcfb42e0dd3635eca 589 SUPERFAMILY SSF53335 396 579 1.56E-15 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase VAPA_1c48030 7f34222e02b61b6bcfb42e0dd3635eca 589 Gene3D G3DSA:3.40.50.1820 3 287 2.8E-48 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c48030 7f34222e02b61b6bcfb42e0dd3635eca 589 SUPERFAMILY SSF53474 10 283 4.12E-33 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c48030 7f34222e02b61b6bcfb42e0dd3635eca 589 Pfam PF12147 Putative methyltransferase 279 587 1.2E-153 T 12-10-2018 IPR022744 Methyltransferase domain, putative VAPA_1c22670 36b2aa3007650cafd03a386e71c4c8f7 289 Gene3D G3DSA:3.40.830.10 1 288 1.2E-74 T 12-10-2018 VAPA_1c22670 36b2aa3007650cafd03a386e71c4c8f7 289 Pfam PF02900 Catalytic LigB subunit of aromatic ring-opening dioxygenase 7 280 1.4E-61 T 12-10-2018 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 VAPA_1c22670 36b2aa3007650cafd03a386e71c4c8f7 289 TIGRFAM TIGR02298 HpaD_Fe: 3,4-dihydroxyphenylacetate 2,3-dioxygenase 1 282 7.6E-144 T 12-10-2018 IPR011984 3,4-dihydroxyphenylacetate 2,3-dioxygenase GO:0008687 KEGG: 00350+1.13.11.15 VAPA_1c22670 36b2aa3007650cafd03a386e71c4c8f7 289 SUPERFAMILY SSF53213 12 280 1.7E-51 T 12-10-2018 VAPA_2c02850 c4c533f5b3aa9f66e9c06c3c4b8816e7 277 SUPERFAMILY SSF51556 1 277 8.17E-55 T 12-10-2018 IPR032466 Metal-dependent hydrolase VAPA_2c02850 c4c533f5b3aa9f66e9c06c3c4b8816e7 277 Gene3D G3DSA:3.20.20.140 1 276 3.9E-81 T 12-10-2018 VAPA_2c02850 c4c533f5b3aa9f66e9c06c3c4b8816e7 277 Pfam PF04909 Amidohydrolase 42 277 1.9E-34 T 12-10-2018 IPR006680 Amidohydrolase-related GO:0016787 VAPA_1c22330 f50a37e1778ff9c2c1a903f0612929b1 382 Gene3D G3DSA:1.10.540.10 15 115 2.7E-9 T 12-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 VAPA_1c22330 f50a37e1778ff9c2c1a903f0612929b1 382 PIRSF PIRSF016578 6 238 4.2E-11 T 12-10-2018 VAPA_1c22330 f50a37e1778ff9c2c1a903f0612929b1 382 PIRSF PIRSF016578 242 374 0.12 T 12-10-2018 VAPA_1c22330 f50a37e1778ff9c2c1a903f0612929b1 382 SUPERFAMILY SSF56645 17 231 1.28E-30 T 12-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 VAPA_1c22330 f50a37e1778ff9c2c1a903f0612929b1 382 SUPERFAMILY SSF47203 248 374 2.42E-8 T 12-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 VAPA_1c22330 f50a37e1778ff9c2c1a903f0612929b1 382 Gene3D G3DSA:2.40.110.10 138 232 1.7E-12 T 12-10-2018 VAPA_1c22330 f50a37e1778ff9c2c1a903f0612929b1 382 Gene3D G3DSA:1.20.140.10 244 373 2.0E-6 T 12-10-2018 VAPA_1c22330 f50a37e1778ff9c2c1a903f0612929b1 382 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 252 360 1.1E-4 T 12-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 VAPA_1c22330 f50a37e1778ff9c2c1a903f0612929b1 382 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 19 109 3.2E-6 T 12-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 VAPA_1c27750 74cbeb0fe7c1660cdb7e71fa83989100 52 Gene3D G3DSA:3.10.450.50 8 49 2.1E-5 T 12-10-2018 VAPA_1c27750 74cbeb0fe7c1660cdb7e71fa83989100 52 SUPERFAMILY SSF54427 5 42 5.17E-5 T 12-10-2018 IPR032710 NTF2-like domain superfamily VAPA_1c43430 14dd4459fd774b46f07b8e917ff9529c 582 Gene3D G3DSA:3.30.450.20 41 190 1.3E-62 T 12-10-2018 VAPA_1c43430 14dd4459fd774b46f07b8e917ff9529c 582 Gene3D G3DSA:1.10.287.950 227 521 3.9E-89 T 12-10-2018 VAPA_1c43430 14dd4459fd774b46f07b8e917ff9529c 582 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 331 487 1.5E-55 T 12-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 VAPA_1c43430 14dd4459fd774b46f07b8e917ff9529c 582 SMART SM00283 272 519 2.5E-90 T 12-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 VAPA_1c43430 14dd4459fd774b46f07b8e917ff9529c 582 SMART SM01049 39 133 2.7E-41 T 12-10-2018 IPR033480 Single Cache domain 2 VAPA_1c43430 14dd4459fd774b46f07b8e917ff9529c 582 Pfam PF17200 Single Cache domain 2 44 189 1.6E-42 T 12-10-2018 IPR033480 Single Cache domain 2 VAPA_1c43430 14dd4459fd774b46f07b8e917ff9529c 582 SUPERFAMILY SSF58104 240 523 9.55E-74 T 12-10-2018 VAPA_1c48280 9bc7295c6da3c7a542eeed9513c6e897 121 Gene3D G3DSA:2.60.300.12 15 121 1.6E-34 T 12-10-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 VAPA_1c48280 9bc7295c6da3c7a542eeed9513c6e897 121 Pfam PF01521 Iron-sulphur cluster biosynthesis 16 116 6.2E-20 T 12-10-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 VAPA_1c48280 9bc7295c6da3c7a542eeed9513c6e897 121 ProSitePatterns PS01152 Hypothetical hesB/yadR/yfhF family signature. 102 119 - T 12-10-2018 IPR017870 FeS cluster insertion, C-terminal, conserved site Reactome: R-HSA-1362409 VAPA_1c48280 9bc7295c6da3c7a542eeed9513c6e897 121 TIGRFAM TIGR00049 TIGR00049: iron-sulfur cluster assembly accessory protein 16 120 1.2E-38 T 12-10-2018 IPR016092 FeS cluster insertion protein GO:0005198|GO:0051536|GO:0097428 Reactome: R-HSA-1362409 VAPA_1c48280 9bc7295c6da3c7a542eeed9513c6e897 121 Hamap MF_01380 Iron-sulfur cluster insertion protein ErpA [erpA]. 1 121 36.834 T 12-10-2018 IPR023063 FeS cluster insertion protein ErpA GO:0097428 VAPA_1c48280 9bc7295c6da3c7a542eeed9513c6e897 121 SUPERFAMILY SSF89360 16 110 2.55E-31 T 12-10-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 VAPA_1c07110 003417ed056f4c09215119b365bd2262 533 PRINTS PR00145 Argininosuccinate lyase family signature 223 239 2.6E-13 T 12-10-2018 VAPA_1c07110 003417ed056f4c09215119b365bd2262 533 PRINTS PR00145 Argininosuccinate lyase family signature 307 323 2.6E-13 T 12-10-2018 VAPA_1c07110 003417ed056f4c09215119b365bd2262 533 PRINTS PR00145 Argininosuccinate lyase family signature 172 192 2.6E-13 T 12-10-2018 VAPA_1c07110 003417ed056f4c09215119b365bd2262 533 PRINTS PR00145 Argininosuccinate lyase family signature 263 287 2.6E-13 T 12-10-2018 VAPA_1c07110 003417ed056f4c09215119b365bd2262 533 PRINTS PR00145 Argininosuccinate lyase family signature 131 153 2.6E-13 T 12-10-2018 VAPA_1c07110 003417ed056f4c09215119b365bd2262 533 SUPERFAMILY SSF48557 41 502 4.71E-72 T 12-10-2018 IPR008948 L-Aspartase-like GO:0003824 VAPA_1c07110 003417ed056f4c09215119b365bd2262 533 Pfam PF00206 Lyase 127 332 4.6E-22 T 12-10-2018 IPR022761 Fumarate lyase, N-terminal VAPA_1c07110 003417ed056f4c09215119b365bd2262 533 PRINTS PR00149 Fumarate lyase superfamily signature 132 150 2.6E-6 T 12-10-2018 IPR000362 Fumarate lyase family VAPA_1c07110 003417ed056f4c09215119b365bd2262 533 PRINTS PR00149 Fumarate lyase superfamily signature 177 195 2.6E-6 T 12-10-2018 IPR000362 Fumarate lyase family VAPA_1c07110 003417ed056f4c09215119b365bd2262 533 PRINTS PR00149 Fumarate lyase superfamily signature 307 323 2.6E-6 T 12-10-2018 IPR000362 Fumarate lyase family VAPA_1c07110 003417ed056f4c09215119b365bd2262 533 Pfam PF14698 Argininosuccinate lyase C-terminal 396 477 7.9E-9 T 12-10-2018 IPR029419 Argininosuccinate lyase, C-terminal KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 VAPA_1c07110 003417ed056f4c09215119b365bd2262 533 Gene3D G3DSA:1.20.200.10 137 492 2.4E-84 T 12-10-2018 VAPA_1c07110 003417ed056f4c09215119b365bd2262 533 Gene3D G3DSA:1.10.40.30 394 479 2.4E-84 T 12-10-2018 VAPA_1c50170 9c4a55ae5ef35bdfa3ca13137b11493f 368 Gene3D G3DSA:3.40.50.2300 41 298 1.4E-108 T 12-10-2018 VAPA_1c50170 9c4a55ae5ef35bdfa3ca13137b11493f 368 SUPERFAMILY SSF53822 40 246 8.63E-6 T 12-10-2018 IPR028082 Periplasmic binding protein-like I VAPA_1c50170 9c4a55ae5ef35bdfa3ca13137b11493f 368 Gene3D G3DSA:3.40.50.2300 143 360 1.4E-108 T 12-10-2018 VAPA_1c50170 9c4a55ae5ef35bdfa3ca13137b11493f 368 Pfam PF02608 ABC transporter substrate-binding protein PnrA-like 40 301 1.9E-43 T 12-10-2018 IPR003760 ABC transporter substrate-binding protein PnrA-like GO:0005886 VAPA_2c03370 fcdf3a2068c26888cd42e9c2f6df6b28 505 Gene3D G3DSA:2.30.42.10 281 386 2.2E-23 T 12-10-2018 VAPA_2c03370 fcdf3a2068c26888cd42e9c2f6df6b28 505 SUPERFAMILY SSF50156 244 368 1.31E-19 T 12-10-2018 IPR036034 PDZ superfamily GO:0005515 VAPA_2c03370 fcdf3a2068c26888cd42e9c2f6df6b28 505 SUPERFAMILY SSF50494 55 277 5.1E-54 T 12-10-2018 IPR009003 Peptidase S1, PA clan VAPA_2c03370 fcdf3a2068c26888cd42e9c2f6df6b28 505 SMART SM00228 397 475 0.0081 T 12-10-2018 IPR001478 PDZ domain GO:0005515 VAPA_2c03370 fcdf3a2068c26888cd42e9c2f6df6b28 505 SMART SM00228 286 368 3.5E-6 T 12-10-2018 IPR001478 PDZ domain GO:0005515 VAPA_2c03370 fcdf3a2068c26888cd42e9c2f6df6b28 505 Pfam PF13365 Trypsin-like peptidase domain 114 247 4.9E-30 T 12-10-2018 VAPA_2c03370 fcdf3a2068c26888cd42e9c2f6df6b28 505 Pfam PF13180 PDZ domain 287 375 7.1E-14 T 12-10-2018 IPR001478 PDZ domain GO:0005515 VAPA_2c03370 fcdf3a2068c26888cd42e9c2f6df6b28 505 Gene3D G3DSA:2.30.42.60 391 501 1.0E-11 T 12-10-2018 VAPA_2c03370 fcdf3a2068c26888cd42e9c2f6df6b28 505 PRINTS PR00834 HtrA/DegQ protease family signature 144 164 1.1E-39 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 VAPA_2c03370 fcdf3a2068c26888cd42e9c2f6df6b28 505 PRINTS PR00834 HtrA/DegQ protease family signature 326 338 1.1E-39 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 VAPA_2c03370 fcdf3a2068c26888cd42e9c2f6df6b28 505 PRINTS PR00834 HtrA/DegQ protease family signature 218 235 1.1E-39 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 VAPA_2c03370 fcdf3a2068c26888cd42e9c2f6df6b28 505 PRINTS PR00834 HtrA/DegQ protease family signature 123 135 1.1E-39 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 VAPA_2c03370 fcdf3a2068c26888cd42e9c2f6df6b28 505 PRINTS PR00834 HtrA/DegQ protease family signature 184 208 1.1E-39 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 VAPA_2c03370 fcdf3a2068c26888cd42e9c2f6df6b28 505 PRINTS PR00834 HtrA/DegQ protease family signature 240 257 1.1E-39 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 VAPA_2c03370 fcdf3a2068c26888cd42e9c2f6df6b28 505 Gene3D G3DSA:2.40.10.120 52 279 3.6E-64 T 12-10-2018 VAPA_2c03370 fcdf3a2068c26888cd42e9c2f6df6b28 505 SUPERFAMILY SSF50156 426 486 7.49E-10 T 12-10-2018 IPR036034 PDZ superfamily GO:0005515 VAPA_1c21970 9854a85a653f8df98048421989bc2b96 299 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 173 291 1.4E-28 T 12-10-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 VAPA_1c21970 9854a85a653f8df98048421989bc2b96 299 SUPERFAMILY SSF51735 8 170 1.7E-35 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c21970 9854a85a653f8df98048421989bc2b96 299 Gene3D G3DSA:1.10.1040.10 170 296 2.7E-34 T 12-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 VAPA_1c21970 9854a85a653f8df98048421989bc2b96 299 Gene3D G3DSA:3.40.50.720 2 169 4.6E-43 T 12-10-2018 VAPA_1c21970 9854a85a653f8df98048421989bc2b96 299 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 9 170 3.0E-36 T 12-10-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 VAPA_1c21970 9854a85a653f8df98048421989bc2b96 299 PIRSF PIRSF000103 1 298 5.2E-67 T 12-10-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 VAPA_1c21970 9854a85a653f8df98048421989bc2b96 299 SUPERFAMILY SSF48179 172 294 2.04E-32 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 VAPA_1c27060 2eb0be33ad0024f608e346cfd449b46b 828 PIRSF PIRSF037149 1 828 0.0 T 12-10-2018 IPR017121 Nitrite reductase [NAD(P)H], large subunit GO:0042128 VAPA_1c27060 2eb0be33ad0024f608e346cfd449b46b 828 Gene3D G3DSA:3.30.413.10 642 792 6.3E-35 T 12-10-2018 VAPA_1c27060 2eb0be33ad0024f608e346cfd449b46b 828 Gene3D G3DSA:3.50.50.60 8 291 2.5E-83 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c27060 2eb0be33ad0024f608e346cfd449b46b 828 TIGRFAM TIGR02374 nitri_red_nirB: nitrite reductase [NAD(P)H], large subunit 7 804 6.7E-275 T 12-10-2018 IPR012744 Nitrite reductase [NAD(P)H] large subunit, NirB GO:0008942|GO:0042128|GO:0050660|GO:0050661|GO:0055114 VAPA_1c27060 2eb0be33ad0024f608e346cfd449b46b 828 ProSitePatterns PS00365 Nitrite and sulfite reductases iron-sulfur/siroheme-binding site. 689 705 - T 12-10-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 VAPA_1c27060 2eb0be33ad0024f608e346cfd449b46b 828 Gene3D G3DSA:1.10.10.1100 432 484 1.1E-9 T 12-10-2018 VAPA_1c27060 2eb0be33ad0024f608e346cfd449b46b 828 Gene3D G3DSA:3.30.390.30 328 407 4.5E-6 T 12-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 VAPA_1c27060 2eb0be33ad0024f608e346cfd449b46b 828 Pfam PF04324 BFD-like [2Fe-2S] binding domain 433 480 9.0E-14 T 12-10-2018 IPR007419 BFD-like [2Fe-2S]-binding domain VAPA_1c27060 2eb0be33ad0024f608e346cfd449b46b 828 Pfam PF04324 BFD-like [2Fe-2S] binding domain 497 547 1.0E-13 T 12-10-2018 IPR007419 BFD-like [2Fe-2S]-binding domain VAPA_1c27060 2eb0be33ad0024f608e346cfd449b46b 828 SUPERFAMILY SSF51905 147 321 2.04E-27 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c27060 2eb0be33ad0024f608e346cfd449b46b 828 Gene3D G3DSA:3.50.50.60 115 255 2.5E-83 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c27060 2eb0be33ad0024f608e346cfd449b46b 828 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 243 259 1.3E-17 T 12-10-2018 VAPA_1c27060 2eb0be33ad0024f608e346cfd449b46b 828 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 152 170 1.3E-17 T 12-10-2018 VAPA_1c27060 2eb0be33ad0024f608e346cfd449b46b 828 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 107 125 1.3E-17 T 12-10-2018 VAPA_1c27060 2eb0be33ad0024f608e346cfd449b46b 828 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 1.3E-17 T 12-10-2018 VAPA_1c27060 2eb0be33ad0024f608e346cfd449b46b 828 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 269 291 1.3E-17 T 12-10-2018 VAPA_1c27060 2eb0be33ad0024f608e346cfd449b46b 828 SUPERFAMILY SSF51905 1 196 2.87E-40 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c27060 2eb0be33ad0024f608e346cfd449b46b 828 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 292 5.1E-50 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 VAPA_1c27060 2eb0be33ad0024f608e346cfd449b46b 828 PRINTS PR00397 Sirohaem Fe-binding site signature 646 664 8.5E-8 T 12-10-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 VAPA_1c27060 2eb0be33ad0024f608e346cfd449b46b 828 PRINTS PR00397 Sirohaem Fe-binding site signature 689 707 8.5E-8 T 12-10-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 VAPA_1c27060 2eb0be33ad0024f608e346cfd449b46b 828 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 244 258 4.9E-12 T 12-10-2018 VAPA_1c27060 2eb0be33ad0024f608e346cfd449b46b 828 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 4.9E-12 T 12-10-2018 VAPA_1c27060 2eb0be33ad0024f608e346cfd449b46b 828 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 152 177 4.9E-12 T 12-10-2018 VAPA_1c27060 2eb0be33ad0024f608e346cfd449b46b 828 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 284 291 4.9E-12 T 12-10-2018 VAPA_1c27060 2eb0be33ad0024f608e346cfd449b46b 828 SUPERFAMILY SSF55124 532 651 2.62E-23 T 12-10-2018 IPR036136 Nitrite/Sulfite reductase ferredoxin-like domain superfamily GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 VAPA_1c27060 2eb0be33ad0024f608e346cfd449b46b 828 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 572 633 4.1E-14 T 12-10-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 VAPA_1c27060 2eb0be33ad0024f608e346cfd449b46b 828 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 643 782 1.1E-25 T 12-10-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 VAPA_1c27060 2eb0be33ad0024f608e346cfd449b46b 828 SUPERFAMILY SSF56014 643 804 1.83E-50 T 12-10-2018 VAPA_1c41720 a22bb6adf442abea630ca3ee91eab0f4 443 Gene3D G3DSA:3.40.50.620 10 336 1.7E-113 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold VAPA_1c41720 a22bb6adf442abea630ca3ee91eab0f4 443 Hamap MF_00140_B Tryptophan--tRNA ligase [trpS]. 8 337 36.818 T 12-10-2018 IPR024109 Tryptophan-tRNA ligase, bacterial-type GO:0004830 KEGG: 00970+6.1.1.2|Reactome: R-HSA-379726 VAPA_1c41720 a22bb6adf442abea630ca3ee91eab0f4 443 Pfam PF00579 tRNA synthetases class I (W and Y) 7 287 7.0E-58 T 12-10-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 VAPA_1c41720 a22bb6adf442abea630ca3ee91eab0f4 443 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 17 26 - T 12-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 VAPA_1c41720 a22bb6adf442abea630ca3ee91eab0f4 443 SUPERFAMILY SSF160113 358 407 2.35E-9 T 12-10-2018 IPR036913 YegP-like superfamily VAPA_1c41720 a22bb6adf442abea630ca3ee91eab0f4 443 Gene3D G3DSA:1.10.240.10 202 304 1.7E-113 T 12-10-2018 VAPA_1c41720 a22bb6adf442abea630ca3ee91eab0f4 443 TIGRFAM TIGR00233 trpS: tryptophan--tRNA ligase 9 336 7.3E-90 T 12-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 VAPA_1c41720 a22bb6adf442abea630ca3ee91eab0f4 443 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 156 177 3.8E-22 T 12-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 VAPA_1c41720 a22bb6adf442abea630ca3ee91eab0f4 443 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 73 92 3.8E-22 T 12-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 VAPA_1c41720 a22bb6adf442abea630ca3ee91eab0f4 443 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 207 217 3.8E-22 T 12-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 VAPA_1c41720 a22bb6adf442abea630ca3ee91eab0f4 443 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 21 37 3.8E-22 T 12-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 VAPA_1c41720 a22bb6adf442abea630ca3ee91eab0f4 443 SUPERFAMILY SSF52374 8 336 4.1E-85 T 12-10-2018 VAPA_1c04890 915b123e2218f194156504da04aceec1 300 SUPERFAMILY SSF103481 38 138 1.12E-12 T 12-10-2018 VAPA_1c04890 915b123e2218f194156504da04aceec1 300 SUPERFAMILY SSF103481 188 286 7.72E-13 T 12-10-2018 VAPA_1c04890 915b123e2218f194156504da04aceec1 300 Pfam PF00892 EamA-like transporter family 153 283 3.7E-18 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 VAPA_1c04890 915b123e2218f194156504da04aceec1 300 Pfam PF00892 EamA-like transporter family 12 137 4.1E-9 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 VAPA_1c43210 ef3d49535cec6abb7c8d821cae6bed85 482 Pfam PF07195 Flagellar hook-associated protein 2 C-terminus 242 465 1.0E-51 T 12-10-2018 IPR010809 Flagellar hook-associated protein 2, C-terminal GO:0007155|GO:0009288 VAPA_1c43210 ef3d49535cec6abb7c8d821cae6bed85 482 Pfam PF02465 Flagellar hook-associated protein 2 N-terminus 11 107 1.4E-21 T 12-10-2018 IPR003481 Flagellar hook-associated protein 2, N-terminal GO:0009424 VAPA_1c51470 cb957731ff69a97886d6f0670c6f4a6f 236 Pfam PF12840 Helix-turn-helix domain 20 74 7.6E-9 T 12-10-2018 VAPA_1c51470 cb957731ff69a97886d6f0670c6f4a6f 236 SUPERFAMILY SSF46785 14 97 1.51E-17 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c51470 cb957731ff69a97886d6f0670c6f4a6f 236 Gene3D G3DSA:1.10.10.10 2 106 1.5E-16 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c51470 cb957731ff69a97886d6f0670c6f4a6f 236 SMART SM00418 20 99 8.2E-11 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 VAPA_1c30360 eaa2ef7b30bf5321edf62bf7724f2318 269 ProSitePatterns PS00923 Aspartate and glutamate racemases signature 1. 70 78 - T 12-10-2018 IPR018187 Asp/Glu racemase, active site 1 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 VAPA_1c30360 eaa2ef7b30bf5321edf62bf7724f2318 269 Gene3D G3DSA:3.40.50.1860 96 210 1.0E-72 T 12-10-2018 VAPA_1c30360 eaa2ef7b30bf5321edf62bf7724f2318 269 SUPERFAMILY SSF53681 4 107 1.31E-29 T 12-10-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 VAPA_1c30360 eaa2ef7b30bf5321edf62bf7724f2318 269 Hamap MF_00258 Glutamate racemase [murI]. 3 258 32.071 T 12-10-2018 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 VAPA_1c30360 eaa2ef7b30bf5321edf62bf7724f2318 269 Gene3D G3DSA:3.40.50.1860 5 255 1.0E-72 T 12-10-2018 VAPA_1c30360 eaa2ef7b30bf5321edf62bf7724f2318 269 TIGRFAM TIGR00067 glut_race: glutamate racemase 5 234 3.0E-53 T 12-10-2018 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 VAPA_1c30360 eaa2ef7b30bf5321edf62bf7724f2318 269 SUPERFAMILY SSF53681 109 258 4.14E-25 T 12-10-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 VAPA_1c30360 eaa2ef7b30bf5321edf62bf7724f2318 269 ProSitePatterns PS00924 Aspartate and glutamate racemases signature 2. 183 193 - T 12-10-2018 IPR033134 Asp/Glu racemase, active site 2 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 VAPA_1c30360 eaa2ef7b30bf5321edf62bf7724f2318 269 Pfam PF01177 Asp/Glu/Hydantoin racemase 5 218 3.9E-32 T 12-10-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 VAPA_1c48400 91fdfbf242317ec7c14d3f4f451367e1 545 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 58 73 - T 12-10-2018 IPR031157 Tr-type G domain, conserved site VAPA_1c48400 91fdfbf242317ec7c14d3f4f451367e1 545 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 17 148 2.3E-23 T 12-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 VAPA_1c48400 91fdfbf242317ec7c14d3f4f451367e1 545 Pfam PF03144 Elongation factor Tu domain 2 321 387 4.0E-9 T 12-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 VAPA_1c48400 91fdfbf242317ec7c14d3f4f451367e1 545 Gene3D G3DSA:3.30.70.3280 397 536 1.9E-47 T 12-10-2018 IPR038467 Peptide chain release factor 3, C-terminal domain superfamily VAPA_1c48400 91fdfbf242317ec7c14d3f4f451367e1 545 TIGRFAM TIGR00503 prfC: peptide chain release factor 3 6 536 1.2E-201 T 12-10-2018 IPR004548 Peptide chain release factor 3 GO:0003924|GO:0005737|GO:0006415 VAPA_1c48400 91fdfbf242317ec7c14d3f4f451367e1 545 Gene3D G3DSA:3.40.50.300 21 274 1.8E-102 T 12-10-2018 VAPA_1c48400 91fdfbf242317ec7c14d3f4f451367e1 545 SUPERFAMILY SSF52540 9 277 1.47E-86 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c48400 91fdfbf242317ec7c14d3f4f451367e1 545 Pfam PF00009 Elongation factor Tu GTP binding domain 12 277 1.5E-51 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 VAPA_1c48400 91fdfbf242317ec7c14d3f4f451367e1 545 SUPERFAMILY SSF54980 399 471 3.13E-16 T 12-10-2018 IPR035647 EF-G domain III/V-like VAPA_1c48400 91fdfbf242317ec7c14d3f4f451367e1 545 Hamap MF_00072 Peptide chain release factor 3 [prfC]. 4 534 48.759 T 12-10-2018 IPR004548 Peptide chain release factor 3 GO:0003924|GO:0005737|GO:0006415 VAPA_1c48400 91fdfbf242317ec7c14d3f4f451367e1 545 Pfam PF16658 Class II release factor RF3, C-terminal domain 394 521 2.4E-42 T 12-10-2018 IPR032090 Peptide chain release factor 3, C-terminal VAPA_1c48400 91fdfbf242317ec7c14d3f4f451367e1 545 PRINTS PR00315 GTP-binding elongation factor signature 85 95 1.8E-11 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 VAPA_1c48400 91fdfbf242317ec7c14d3f4f451367e1 545 PRINTS PR00315 GTP-binding elongation factor signature 65 73 1.8E-11 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 VAPA_1c48400 91fdfbf242317ec7c14d3f4f451367e1 545 PRINTS PR00315 GTP-binding elongation factor signature 15 28 1.8E-11 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 VAPA_1c48400 91fdfbf242317ec7c14d3f4f451367e1 545 PRINTS PR00315 GTP-binding elongation factor signature 101 112 1.8E-11 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 VAPA_1c48400 91fdfbf242317ec7c14d3f4f451367e1 545 PRINTS PR00315 GTP-binding elongation factor signature 137 146 1.8E-11 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 VAPA_1c48400 91fdfbf242317ec7c14d3f4f451367e1 545 Gene3D G3DSA:3.40.50.300 14 385 1.8E-102 T 12-10-2018 VAPA_1c48400 91fdfbf242317ec7c14d3f4f451367e1 545 SUPERFAMILY SSF50447 260 398 2.43E-27 T 12-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily VAPA_1c05780 0259820462e441f1eb974a3ef8303032 343 SMART SM00559 64 193 4.9E-28 T 12-10-2018 IPR006164 Ku70/Ku80 beta-barrel domain GO:0003677|GO:0006303 Reactome: R-HSA-164843|Reactome: R-HSA-1834949|Reactome: R-HSA-3270619|Reactome: R-HSA-5693571|Reactome: R-HSA-6798695 VAPA_1c05780 0259820462e441f1eb974a3ef8303032 343 Hamap MF_01875 Non-homologous end joining protein Ku [ku]. 13 277 30.691 T 12-10-2018 IPR009187 Non-homologous end joining protein Ku, prokaryotic type VAPA_1c05780 0259820462e441f1eb974a3ef8303032 343 Gene3D G3DSA:2.40.290.10 14 192 3.3E-16 T 12-10-2018 IPR016194 SPOC-like, C-terminal domain superfamily VAPA_1c05780 0259820462e441f1eb974a3ef8303032 343 SUPERFAMILY SSF100939 13 276 8.63E-48 T 12-10-2018 IPR016194 SPOC-like, C-terminal domain superfamily VAPA_1c05780 0259820462e441f1eb974a3ef8303032 343 PIRSF PIRSF006493 12 343 8.7E-87 T 12-10-2018 IPR009187 Non-homologous end joining protein Ku, prokaryotic type VAPA_1c05780 0259820462e441f1eb974a3ef8303032 343 Pfam PF02735 Ku70/Ku80 beta-barrel domain 23 204 4.1E-34 T 12-10-2018 IPR006164 Ku70/Ku80 beta-barrel domain GO:0003677|GO:0006303 Reactome: R-HSA-164843|Reactome: R-HSA-1834949|Reactome: R-HSA-3270619|Reactome: R-HSA-5693571|Reactome: R-HSA-6798695 VAPA_1c05780 0259820462e441f1eb974a3ef8303032 343 TIGRFAM TIGR02772 Ku_bact: Ku protein 14 278 5.6E-90 T 12-10-2018 IPR009187 Non-homologous end joining protein Ku, prokaryotic type VAPA_1c37890 bb7160067055c71a215138be000976c9 256 SMART SM00382 40 228 6.2E-19 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c37890 bb7160067055c71a215138be000976c9 256 ProSitePatterns PS00211 ABC transporters family signature. 152 166 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_1c37890 bb7160067055c71a215138be000976c9 256 Gene3D G3DSA:3.40.50.300 13 256 3.9E-79 T 12-10-2018 VAPA_1c37890 bb7160067055c71a215138be000976c9 256 Pfam PF00005 ABC transporter 31 180 1.0E-36 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c37890 bb7160067055c71a215138be000976c9 256 SUPERFAMILY SSF52540 15 249 2.1E-78 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c37890 bb7160067055c71a215138be000976c9 256 PIRSF PIRSF039085 12 256 1.7E-110 T 12-10-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 VAPA_1c49390 e9639d99f64a48b8f0f5ae8a3291dca2 302 Gene3D G3DSA:2.60.40.2230 24 171 2.1E-24 T 12-10-2018 IPR038507 YcnI-like superfamily VAPA_1c49390 e9639d99f64a48b8f0f5ae8a3291dca2 302 Pfam PF04314 Copper chaperone PCu(A)C 170 273 2.2E-34 T 12-10-2018 IPR007410 Copper chaperone PCuAC VAPA_1c49390 e9639d99f64a48b8f0f5ae8a3291dca2 302 Pfam PF07987 Domain of unkown function (DUF1775) 26 160 9.7E-25 T 12-10-2018 IPR012533 YcnI-like VAPA_1c49390 e9639d99f64a48b8f0f5ae8a3291dca2 302 SUPERFAMILY SSF110087 161 279 2.22E-39 T 12-10-2018 IPR036182 Copper chaperone PCuAC superfamily VAPA_1c49390 e9639d99f64a48b8f0f5ae8a3291dca2 302 Gene3D G3DSA:2.60.40.1890 173 285 6.5E-35 T 12-10-2018 IPR036182 Copper chaperone PCuAC superfamily VAPA_1c08770 dd503c16ad680b67fc1e3e58cb6c8ef2 277 SUPERFAMILY SSF54637 126 274 1.94E-21 T 12-10-2018 IPR029069 HotDog domain superfamily VAPA_1c08770 dd503c16ad680b67fc1e3e58cb6c8ef2 277 SUPERFAMILY SSF54637 17 100 2.19E-5 T 12-10-2018 IPR029069 HotDog domain superfamily VAPA_1c08770 dd503c16ad680b67fc1e3e58cb6c8ef2 277 Gene3D G3DSA:3.10.129.90 1 277 4.4E-85 T 12-10-2018 VAPA_1c08770 dd503c16ad680b67fc1e3e58cb6c8ef2 277 Pfam PF13622 Thioesterase-like superfamily 27 274 1.2E-40 T 12-10-2018 VAPA_1c51120 2666da6e30fb388ab900d3ed9f51e0c9 227 Gene3D G3DSA:3.40.50.1820 2 225 3.3E-54 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c51120 2666da6e30fb388ab900d3ed9f51e0c9 227 SUPERFAMILY SSF53474 2 226 3.98E-47 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c51120 2666da6e30fb388ab900d3ed9f51e0c9 227 Pfam PF01738 Dienelactone hydrolase family 15 225 7.1E-50 T 12-10-2018 IPR002925 Dienelactone hydrolase GO:0016787 VAPA_1c09390 a723d81e382a19f13b2a215ca7338700 311 SUPERFAMILY SSF103481 53 154 8.89E-13 T 12-10-2018 VAPA_1c09390 a723d81e382a19f13b2a215ca7338700 311 Pfam PF00892 EamA-like transporter family 168 299 4.0E-13 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 VAPA_1c09390 a723d81e382a19f13b2a215ca7338700 311 Pfam PF00892 EamA-like transporter family 20 152 6.1E-22 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 VAPA_1c09390 a723d81e382a19f13b2a215ca7338700 311 SUPERFAMILY SSF103481 200 302 6.28E-13 T 12-10-2018 VAPA_1c19690 81866db982a80f902335e7ec3ec41da4 358 TIGRFAM TIGR00468 pheS: phenylalanine--tRNA ligase, alpha subunit 38 357 6.6E-91 T 12-10-2018 IPR004529 Phenylalanyl-tRNA synthetase, class IIc, alpha subunit GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 VAPA_1c19690 81866db982a80f902335e7ec3ec41da4 358 Gene3D G3DSA:3.30.930.10 7 358 1.5E-106 T 12-10-2018 VAPA_1c19690 81866db982a80f902335e7ec3ec41da4 358 SUPERFAMILY SSF55681 92 357 8.02E-70 T 12-10-2018 VAPA_1c19690 81866db982a80f902335e7ec3ec41da4 358 Pfam PF01409 tRNA synthetases class II core domain (F) 92 357 1.4E-83 T 12-10-2018 IPR002319 Phenylalanyl-tRNA synthetase GO:0000049|GO:0004812|GO:0005524|GO:0005737|GO:0043039 KEGG: 00970+6.1.1.20 VAPA_1c19690 81866db982a80f902335e7ec3ec41da4 358 Hamap MF_00281 Phenylalanine--tRNA ligase alpha subunit [pheS]. 8 357 43.602 T 12-10-2018 IPR022911 Phenylalanine-tRNA ligase alpha chain 1, bacterial GO:0004826 KEGG: 00970+6.1.1.20 VAPA_1c19690 81866db982a80f902335e7ec3ec41da4 358 Pfam PF02912 Aminoacyl tRNA synthetase class II, N-terminal domain 20 86 2.1E-20 T 12-10-2018 IPR004188 Phenylalanine-tRNA ligase, class II, N-terminal GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 VAPA_1c19690 81866db982a80f902335e7ec3ec41da4 358 SUPERFAMILY SSF46589 14 99 1.05E-17 T 12-10-2018 IPR010978 Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm GO:0000166 VAPA_2c09020 d9ba5d59e6274f1d40dcb329ab32d669 397 SUPERFAMILY SSF53474 2 253 2.13E-41 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_2c09020 d9ba5d59e6274f1d40dcb329ab32d669 397 Pfam PF12146 Serine aminopeptidase, S33 48 146 1.6E-10 T 12-10-2018 IPR022742 Serine aminopeptidase, S33 VAPA_2c09020 d9ba5d59e6274f1d40dcb329ab32d669 397 Pfam PF02566 OsmC-like protein 298 389 1.4E-14 T 12-10-2018 IPR003718 OsmC/Ohr family VAPA_2c09020 d9ba5d59e6274f1d40dcb329ab32d669 397 Gene3D G3DSA:3.40.50.1820 3 254 1.6E-54 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_2c09020 d9ba5d59e6274f1d40dcb329ab32d669 397 SUPERFAMILY SSF82784 229 389 1.83E-32 T 12-10-2018 IPR036102 OsmC/Ohr superfamily VAPA_2c09020 d9ba5d59e6274f1d40dcb329ab32d669 397 Gene3D G3DSA:3.30.300.20 260 392 3.6E-28 T 12-10-2018 IPR015946 K homology domain-like, alpha/beta VAPA_1c23590 bf997a2c4d68044050f079be77304cef 268 TIGRFAM TIGR03302 OM_YfiO: outer membrane assembly lipoprotein YfiO 10 252 4.1E-82 T 12-10-2018 IPR017689 Outer membrane protein assembly factor BamD VAPA_1c23590 bf997a2c4d68044050f079be77304cef 268 Pfam PF13525 Outer membrane lipoprotein 37 240 3.5E-55 T 12-10-2018 IPR039565 Outer membrane lipoprotein BamD-like VAPA_1c23590 bf997a2c4d68044050f079be77304cef 268 Gene3D G3DSA:1.25.40.10 36 257 1.3E-51 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 VAPA_1c23590 bf997a2c4d68044050f079be77304cef 268 SUPERFAMILY SSF48452 44 231 1.46E-7 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 VAPA_1c23590 bf997a2c4d68044050f079be77304cef 268 Hamap MF_00922 Outer membrane protein assembly factor BamD [bamD]. 7 247 37.339 T 12-10-2018 IPR017689 Outer membrane protein assembly factor BamD VAPA_1c17880 12d731b3a4b7f6f4450fc31db9e84313 170 Gene3D G3DSA:3.40.630.30 15 156 3.1E-20 T 12-10-2018 VAPA_1c17880 12d731b3a4b7f6f4450fc31db9e84313 170 Pfam PF13508 Acetyltransferase (GNAT) domain 63 136 4.5E-11 T 12-10-2018 IPR000182 GNAT domain VAPA_1c17880 12d731b3a4b7f6f4450fc31db9e84313 170 SUPERFAMILY SSF55729 27 158 1.13E-17 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase VAPA_2c03470 add55286a7951386b47e1355a00981a1 262 SUPERFAMILY SSF46785 170 249 3.67E-14 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_2c03470 add55286a7951386b47e1355a00981a1 262 SMART SM00100 35 152 1.6E-6 T 12-10-2018 IPR000595 Cyclic nucleotide-binding domain VAPA_2c03470 add55286a7951386b47e1355a00981a1 262 Gene3D G3DSA:1.10.10.10 170 253 1.1E-19 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_2c03470 add55286a7951386b47e1355a00981a1 262 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 213 228 1.4E-9 T 12-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 VAPA_2c03470 add55286a7951386b47e1355a00981a1 262 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 197 213 1.4E-9 T 12-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 VAPA_2c03470 add55286a7951386b47e1355a00981a1 262 Pfam PF00027 Cyclic nucleotide-binding domain 53 137 1.2E-15 T 12-10-2018 IPR000595 Cyclic nucleotide-binding domain VAPA_2c03470 add55286a7951386b47e1355a00981a1 262 SMART SM00419 191 242 1.3E-12 T 12-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 VAPA_2c03470 add55286a7951386b47e1355a00981a1 262 SUPERFAMILY SSF51206 52 163 3.4E-22 T 12-10-2018 IPR018490 Cyclic nucleotide-binding-like VAPA_2c03470 add55286a7951386b47e1355a00981a1 262 Pfam PF13545 Crp-like helix-turn-helix domain 172 248 1.0E-16 T 12-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 VAPA_2c03470 add55286a7951386b47e1355a00981a1 262 Gene3D G3DSA:2.60.120.10 47 166 3.5E-30 T 12-10-2018 IPR014710 RmlC-like jelly roll fold VAPA_2c03470 add55286a7951386b47e1355a00981a1 262 ProSitePatterns PS00042 Crp-type HTH domain signature. 199 222 - T 12-10-2018 IPR018335 Transcription regulator HTH, Crp-type, conserved site GO:0003700|GO:0005622|GO:0006355 VAPA_1c32410 ced5934b5cfcbfe878ef54edf44dcbc8 272 Pfam PF13531 Bacterial extracellular solute-binding protein 40 266 2.4E-31 T 12-10-2018 VAPA_1c32410 ced5934b5cfcbfe878ef54edf44dcbc8 272 Gene3D G3DSA:3.40.190.10 42 265 1.4E-29 T 12-10-2018 VAPA_1c32410 ced5934b5cfcbfe878ef54edf44dcbc8 272 Gene3D G3DSA:3.40.190.10 122 229 1.4E-29 T 12-10-2018 VAPA_1c32410 ced5934b5cfcbfe878ef54edf44dcbc8 272 SUPERFAMILY SSF53850 39 268 4.03E-40 T 12-10-2018 VAPA_1c14910 6d01ee76bf41e121eed2e2bd3db0f3a7 496 TIGRFAM TIGR02037 degP_htrA_DO: peptidase Do 44 489 8.4E-151 T 12-10-2018 IPR011782 Peptidase S1C, Do GO:0004252|GO:0006508 VAPA_1c14910 6d01ee76bf41e121eed2e2bd3db0f3a7 496 SUPERFAMILY SSF50156 245 369 1.84E-22 T 12-10-2018 IPR036034 PDZ superfamily GO:0005515 VAPA_1c14910 6d01ee76bf41e121eed2e2bd3db0f3a7 496 SUPERFAMILY SSF50494 42 278 7.23E-64 T 12-10-2018 IPR009003 Peptidase S1, PA clan VAPA_1c14910 6d01ee76bf41e121eed2e2bd3db0f3a7 496 SMART SM00228 407 485 9.6E-7 T 12-10-2018 IPR001478 PDZ domain GO:0005515 VAPA_1c14910 6d01ee76bf41e121eed2e2bd3db0f3a7 496 SMART SM00228 287 369 4.2E-10 T 12-10-2018 IPR001478 PDZ domain GO:0005515 VAPA_1c14910 6d01ee76bf41e121eed2e2bd3db0f3a7 496 Gene3D G3DSA:2.40.10.120 43 280 1.4E-80 T 12-10-2018 VAPA_1c14910 6d01ee76bf41e121eed2e2bd3db0f3a7 496 Gene3D G3DSA:2.30.42.10 285 386 3.6E-26 T 12-10-2018 VAPA_1c14910 6d01ee76bf41e121eed2e2bd3db0f3a7 496 PRINTS PR00834 HtrA/DegQ protease family signature 219 236 2.2E-50 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 VAPA_1c14910 6d01ee76bf41e121eed2e2bd3db0f3a7 496 PRINTS PR00834 HtrA/DegQ protease family signature 126 138 2.2E-50 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 VAPA_1c14910 6d01ee76bf41e121eed2e2bd3db0f3a7 496 PRINTS PR00834 HtrA/DegQ protease family signature 147 167 2.2E-50 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 VAPA_1c14910 6d01ee76bf41e121eed2e2bd3db0f3a7 496 PRINTS PR00834 HtrA/DegQ protease family signature 241 258 2.2E-50 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 VAPA_1c14910 6d01ee76bf41e121eed2e2bd3db0f3a7 496 PRINTS PR00834 HtrA/DegQ protease family signature 187 211 2.2E-50 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 VAPA_1c14910 6d01ee76bf41e121eed2e2bd3db0f3a7 496 PRINTS PR00834 HtrA/DegQ protease family signature 327 339 2.2E-50 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 VAPA_1c14910 6d01ee76bf41e121eed2e2bd3db0f3a7 496 Gene3D G3DSA:2.30.42.60 398 494 4.6E-13 T 12-10-2018 VAPA_1c14910 6d01ee76bf41e121eed2e2bd3db0f3a7 496 Pfam PF13365 Trypsin-like peptidase domain 117 248 3.0E-33 T 12-10-2018 VAPA_1c14910 6d01ee76bf41e121eed2e2bd3db0f3a7 496 SUPERFAMILY SSF50156 408 494 8.15E-11 T 12-10-2018 IPR036034 PDZ superfamily GO:0005515 VAPA_1c14910 6d01ee76bf41e121eed2e2bd3db0f3a7 496 Pfam PF13180 PDZ domain 288 378 9.9E-17 T 12-10-2018 IPR001478 PDZ domain GO:0005515 VAPA_1c14910 6d01ee76bf41e121eed2e2bd3db0f3a7 496 Pfam PF13180 PDZ domain 435 485 5.1E-7 T 12-10-2018 IPR001478 PDZ domain GO:0005515 VAPA_2c01970 4159e1f8211410181a5387f21b37ac8a 512 SMART SM00267 327 505 2.3E-63 T 12-10-2018 IPR000160 GGDEF domain VAPA_2c01970 4159e1f8211410181a5387f21b37ac8a 512 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 334 504 2.2E-48 T 12-10-2018 IPR000160 GGDEF domain VAPA_2c01970 4159e1f8211410181a5387f21b37ac8a 512 Gene3D G3DSA:3.30.70.270 324 505 2.3E-53 T 12-10-2018 VAPA_2c01970 4159e1f8211410181a5387f21b37ac8a 512 Gene3D G3DSA:3.30.450.20 29 181 1.5E-38 T 12-10-2018 VAPA_2c01970 4159e1f8211410181a5387f21b37ac8a 512 Gene3D G3DSA:3.30.450.20 183 274 1.7E-24 T 12-10-2018 VAPA_2c01970 4159e1f8211410181a5387f21b37ac8a 512 Pfam PF02743 Cache domain 39 239 3.3E-17 T 12-10-2018 IPR033479 Double Cache domain 1 VAPA_2c01970 4159e1f8211410181a5387f21b37ac8a 512 Pfam PF00990 Diguanylate cyclase, GGDEF domain 339 501 1.6E-45 T 12-10-2018 IPR000160 GGDEF domain VAPA_2c01970 4159e1f8211410181a5387f21b37ac8a 512 SUPERFAMILY SSF55073 343 503 5.49E-43 T 12-10-2018 IPR029787 Nucleotide cyclase VAPA_1c54790 10f3da05e584cd39948b2144c4a376fb 349 Pfam PF09851 Short C-terminal domain 319 345 1.4E-8 T 12-10-2018 IPR018649 SHOCT domain VAPA_1c54790 10f3da05e584cd39948b2144c4a376fb 349 Pfam PF13421 SPFH domain-Band 7 family 26 235 3.2E-77 T 12-10-2018 IPR033880 SPFH domain, YdjI-like VAPA_1c54790 10f3da05e584cd39948b2144c4a376fb 349 SUPERFAMILY SSF117892 90 231 5.23E-9 T 12-10-2018 IPR036013 Band 7/SPFH domain superfamily VAPA_1c29730 f78e3b2837bf11c3d3f3fd511bb52149 469 Gene3D G3DSA:3.30.450.300 41 166 1.8E-44 T 12-10-2018 IPR038421 Sensor histidine kinase RisS, periplasmic domain superfamily VAPA_1c29730 f78e3b2837bf11c3d3f3fd511bb52149 469 Pfam PF00672 HAMP domain 189 239 1.3E-6 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 VAPA_1c29730 f78e3b2837bf11c3d3f3fd511bb52149 469 SUPERFAMILY SSF55874 293 459 2.36E-32 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_1c29730 f78e3b2837bf11c3d3f3fd511bb52149 469 SMART SM00304 189 243 4.7E-4 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 VAPA_1c29730 f78e3b2837bf11c3d3f3fd511bb52149 469 SMART SM00387 341 456 1.8E-21 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase VAPA_1c29730 f78e3b2837bf11c3d3f3fd511bb52149 469 PRINTS PR00344 Bacterial sensor protein C-terminal signature 440 453 3.8E-12 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c29730 f78e3b2837bf11c3d3f3fd511bb52149 469 PRINTS PR00344 Bacterial sensor protein C-terminal signature 382 396 3.8E-12 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c29730 f78e3b2837bf11c3d3f3fd511bb52149 469 PRINTS PR00344 Bacterial sensor protein C-terminal signature 400 410 3.8E-12 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c29730 f78e3b2837bf11c3d3f3fd511bb52149 469 PRINTS PR00344 Bacterial sensor protein C-terminal signature 416 434 3.8E-12 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c29730 f78e3b2837bf11c3d3f3fd511bb52149 469 Pfam PF00512 His Kinase A (phospho-acceptor) domain 248 301 7.8E-8 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 VAPA_1c29730 f78e3b2837bf11c3d3f3fd511bb52149 469 SMART SM00388 244 303 2.6E-9 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 VAPA_1c29730 f78e3b2837bf11c3d3f3fd511bb52149 469 Gene3D G3DSA:3.30.565.10 304 457 2.5E-31 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_1c29730 f78e3b2837bf11c3d3f3fd511bb52149 469 Gene3D G3DSA:1.10.287.130 187 298 3.7E-19 T 12-10-2018 VAPA_1c29730 f78e3b2837bf11c3d3f3fd511bb52149 469 SUPERFAMILY SSF47384 230 301 6.67E-12 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 VAPA_1c29730 f78e3b2837bf11c3d3f3fd511bb52149 469 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 341 453 5.3E-18 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase VAPA_1c29730 f78e3b2837bf11c3d3f3fd511bb52149 469 Pfam PF16524 Periplasmic domain of Sensor histidine kinase RisS 55 160 3.9E-38 T 12-10-2018 IPR032408 Sensor histidine kinase RisS, periplasmic domain VAPA_1c36600 99d4adb63d24bf3a097a4072d7bf878f 1023 SUPERFAMILY SSF46894 947 1014 5.78E-20 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 VAPA_1c36600 99d4adb63d24bf3a097a4072d7bf878f 1023 Pfam PF00196 Bacterial regulatory proteins, luxR family 956 1010 2.8E-16 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_1c36600 99d4adb63d24bf3a097a4072d7bf878f 1023 SMART SM00421 953 1010 1.8E-24 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_1c36600 99d4adb63d24bf3a097a4072d7bf878f 1023 Gene3D G3DSA:1.25.40.10 550 842 1.7E-10 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 VAPA_1c36600 99d4adb63d24bf3a097a4072d7bf878f 1023 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 956 970 1.4E-8 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_1c36600 99d4adb63d24bf3a097a4072d7bf878f 1023 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 986 998 1.4E-8 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_1c36600 99d4adb63d24bf3a097a4072d7bf878f 1023 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 970 986 1.4E-8 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_1c36600 99d4adb63d24bf3a097a4072d7bf878f 1023 Pfam PF13191 AAA ATPase domain 42 218 1.9E-27 T 12-10-2018 VAPA_1c36600 99d4adb63d24bf3a097a4072d7bf878f 1023 SUPERFAMILY SSF52540 41 266 3.51E-12 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c36600 99d4adb63d24bf3a097a4072d7bf878f 1023 Gene3D G3DSA:1.10.10.10 894 1022 1.6E-24 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c36600 99d4adb63d24bf3a097a4072d7bf878f 1023 ProSitePatterns PS00622 LuxR-type HTH domain signature. 970 997 - T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_1c35610 01a4f06a1ee28190179a93780d672383 158 Gene3D G3DSA:3.10.129.10 13 158 3.6E-45 T 12-10-2018 VAPA_1c35610 01a4f06a1ee28190179a93780d672383 158 SUPERFAMILY SSF54637 14 157 5.3E-33 T 12-10-2018 IPR029069 HotDog domain superfamily VAPA_1c35610 01a4f06a1ee28190179a93780d672383 158 Pfam PF01575 MaoC like domain 28 122 3.7E-13 T 12-10-2018 IPR002539 MaoC-like dehydratase domain VAPA_1c19700 5c0af04c1ebc7f2f80e179da74f05d3e 813 Gene3D G3DSA:3.30.930.10 489 695 4.8E-59 T 12-10-2018 VAPA_1c19700 5c0af04c1ebc7f2f80e179da74f05d3e 813 SUPERFAMILY SSF54991 701 812 7.06E-20 T 12-10-2018 IPR036690 Ferrodoxin-fold anticodon-binding domain superfamily KEGG: 00970+6.1.1.20 VAPA_1c19700 5c0af04c1ebc7f2f80e179da74f05d3e 813 Gene3D G3DSA:3.30.56.10 406 479 1.6E-22 T 12-10-2018 VAPA_1c19700 5c0af04c1ebc7f2f80e179da74f05d3e 813 Pfam PF03484 tRNA synthetase B5 domain 409 474 3.6E-18 T 12-10-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 VAPA_1c19700 5c0af04c1ebc7f2f80e179da74f05d3e 813 SMART SM00874 406 474 9.5E-26 T 12-10-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 VAPA_1c19700 5c0af04c1ebc7f2f80e179da74f05d3e 813 SUPERFAMILY SSF46955 407 478 2.56E-18 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily VAPA_1c19700 5c0af04c1ebc7f2f80e179da74f05d3e 813 SUPERFAMILY SSF56037 201 395 2.62E-66 T 12-10-2018 VAPA_1c19700 5c0af04c1ebc7f2f80e179da74f05d3e 813 Pfam PF03483 B3/4 domain 218 390 1.7E-58 T 12-10-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 VAPA_1c19700 5c0af04c1ebc7f2f80e179da74f05d3e 813 TIGRFAM TIGR00472 pheT_bact: phenylalanine--tRNA ligase, beta subunit 1 812 1.4E-217 T 12-10-2018 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 VAPA_1c19700 5c0af04c1ebc7f2f80e179da74f05d3e 813 Pfam PF01588 Putative tRNA binding domain 45 150 2.1E-23 T 12-10-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 VAPA_1c19700 5c0af04c1ebc7f2f80e179da74f05d3e 813 Pfam PF03147 Ferredoxin-fold anticodon binding domain 706 812 1.7E-26 T 12-10-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 VAPA_1c19700 5c0af04c1ebc7f2f80e179da74f05d3e 813 Gene3D G3DSA:3.30.70.380 707 812 1.6E-22 T 12-10-2018 IPR036690 Ferrodoxin-fold anticodon-binding domain superfamily KEGG: 00970+6.1.1.20 VAPA_1c19700 5c0af04c1ebc7f2f80e179da74f05d3e 813 Hamap MF_00283 Phenylalanine--tRNA ligase beta subunit [pheT]. 1 806 42.139 T 12-10-2018 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 VAPA_1c19700 5c0af04c1ebc7f2f80e179da74f05d3e 813 SUPERFAMILY SSF50249 38 202 5.88E-45 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold VAPA_1c19700 5c0af04c1ebc7f2f80e179da74f05d3e 813 SUPERFAMILY SSF55681 470 694 2.48E-48 T 12-10-2018 VAPA_1c19700 5c0af04c1ebc7f2f80e179da74f05d3e 813 SMART SM00873 217 390 2.3E-76 T 12-10-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 VAPA_1c19700 5c0af04c1ebc7f2f80e179da74f05d3e 813 Gene3D G3DSA:3.50.40.10 202 399 5.4E-68 T 12-10-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 KEGG: 00970+6.1.1.20 VAPA_1c19700 5c0af04c1ebc7f2f80e179da74f05d3e 813 Gene3D G3DSA:3.30.56.10 5 186 7.3E-63 T 12-10-2018 VAPA_1c19700 5c0af04c1ebc7f2f80e179da74f05d3e 813 SMART SM00896 706 812 9.2E-37 T 12-10-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 VAPA_1c19700 5c0af04c1ebc7f2f80e179da74f05d3e 813 Gene3D G3DSA:2.40.50.140 39 159 7.3E-63 T 12-10-2018 VAPA_1c32530 c2ce938427fcd26b671427bc5f0b78e4 264 PIRSF PIRSF005227 1 264 2.7E-81 T 12-10-2018 IPR011182 L-aspartate dehydrogenase GO:0009435|GO:0033735|GO:0055114 KEGG: 00760+1.4.1.21 VAPA_1c32530 c2ce938427fcd26b671427bc5f0b78e4 264 Pfam PF01958 Domain of unknown function DUF108 165 252 7.3E-35 T 12-10-2018 IPR002811 Aspartate dehydrogenase GO:0006742|GO:0016491|GO:0019363|GO:0055114 KEGG: 00760+1.4.1.21 VAPA_1c32530 c2ce938427fcd26b671427bc5f0b78e4 264 Gene3D G3DSA:3.40.50.720 6 257 4.2E-69 T 12-10-2018 VAPA_1c32530 c2ce938427fcd26b671427bc5f0b78e4 264 SUPERFAMILY SSF51735 5 150 1.1E-18 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c32530 c2ce938427fcd26b671427bc5f0b78e4 264 Gene3D G3DSA:3.30.360.10 121 239 4.2E-69 T 12-10-2018 VAPA_1c32530 c2ce938427fcd26b671427bc5f0b78e4 264 SUPERFAMILY SSF55347 121 234 3.99E-33 T 12-10-2018 VAPA_1c32530 c2ce938427fcd26b671427bc5f0b78e4 264 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 10 116 7.8E-17 T 12-10-2018 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 VAPA_1c32530 c2ce938427fcd26b671427bc5f0b78e4 264 Hamap MF_01265 Probable L-aspartate dehydrogenase [nadX]. 3 264 35.371 T 12-10-2018 IPR020626 L-aspartate dehydrogenase, prokaryotic GO:0009435|GO:0033735|GO:0055114 KEGG: 00760+1.4.1.21 VAPA_1c09890 06c74ad79d061aee8c843a3a0c43dc1a 686 SMART SM00955 235 531 6.5E-67 T 12-10-2018 IPR001900 Ribonuclease II/R GO:0003723|GO:0004540 VAPA_1c09890 06c74ad79d061aee8c843a3a0c43dc1a 686 SUPERFAMILY SSF50249 229 581 6.85E-73 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold VAPA_1c09890 06c74ad79d061aee8c843a3a0c43dc1a 686 Pfam PF00773 RNB domain 493 528 1.5E-8 T 12-10-2018 IPR001900 Ribonuclease II/R GO:0003723|GO:0004540 VAPA_1c09890 06c74ad79d061aee8c843a3a0c43dc1a 686 Pfam PF00773 RNB domain 242 483 8.5E-36 T 12-10-2018 IPR001900 Ribonuclease II/R GO:0003723|GO:0004540 VAPA_1c41450 5a4376c7e222dec19adc6dc55ee2d070 214 SUPERFAMILY SSF46894 143 207 1.87E-18 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 VAPA_1c41450 5a4376c7e222dec19adc6dc55ee2d070 214 SMART SM00421 147 204 2.1E-18 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_1c41450 5a4376c7e222dec19adc6dc55ee2d070 214 SMART SM00448 9 122 2.0E-30 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_1c41450 5a4376c7e222dec19adc6dc55ee2d070 214 SUPERFAMILY SSF52172 8 138 6.97E-33 T 12-10-2018 IPR011006 CheY-like superfamily VAPA_1c41450 5a4376c7e222dec19adc6dc55ee2d070 214 Pfam PF00072 Response regulator receiver domain 12 123 3.6E-26 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_1c41450 5a4376c7e222dec19adc6dc55ee2d070 214 Gene3D G3DSA:3.40.50.12740 9 208 5.0E-63 T 12-10-2018 VAPA_1c41450 5a4376c7e222dec19adc6dc55ee2d070 214 Pfam PF00196 Bacterial regulatory proteins, luxR family 150 204 1.7E-16 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_1c41450 5a4376c7e222dec19adc6dc55ee2d070 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 164 180 1.9E-11 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_1c41450 5a4376c7e222dec19adc6dc55ee2d070 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 180 192 1.9E-11 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_1c41450 5a4376c7e222dec19adc6dc55ee2d070 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 150 164 1.9E-11 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_1c41450 5a4376c7e222dec19adc6dc55ee2d070 214 ProSitePatterns PS00622 LuxR-type HTH domain signature. 164 191 - T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_1c48990 f806eb9735303214e7834221aead3cdf 321 Gene3D G3DSA:3.40.50.10330 8 135 2.7E-25 T 12-10-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, N-terminal GO:0003951 VAPA_1c48990 f806eb9735303214e7834221aead3cdf 321 SUPERFAMILY SSF111331 11 311 5.45E-57 T 12-10-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain superfamily VAPA_1c48990 f806eb9735303214e7834221aead3cdf 321 SMART SM00046 11 136 0.0016 T 12-10-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 VAPA_1c48990 f806eb9735303214e7834221aead3cdf 321 Gene3D G3DSA:2.60.200.40 136 302 1.5E-20 T 12-10-2018 VAPA_1c48990 f806eb9735303214e7834221aead3cdf 321 Pfam PF00781 Diacylglycerol kinase catalytic domain 12 135 2.8E-21 T 12-10-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 VAPA_1c23390 38fd710970c3fe7fd37d67cba7fedb3f 846 Pfam PF00512 His Kinase A (phospho-acceptor) domain 601 667 6.2E-10 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 VAPA_1c23390 38fd710970c3fe7fd37d67cba7fedb3f 846 SMART SM00387 712 832 3.1E-24 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase VAPA_1c23390 38fd710970c3fe7fd37d67cba7fedb3f 846 SMART SM00388 600 670 2.2E-7 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 VAPA_1c23390 38fd710970c3fe7fd37d67cba7fedb3f 846 SMART SM00091 331 398 3.6E-10 T 12-10-2018 IPR000014 PAS domain VAPA_1c23390 38fd710970c3fe7fd37d67cba7fedb3f 846 Gene3D G3DSA:1.10.287.130 605 667 1.8E-20 T 12-10-2018 VAPA_1c23390 38fd710970c3fe7fd37d67cba7fedb3f 846 SMART SM00086 405 447 0.005 T 12-10-2018 IPR001610 PAC motif VAPA_1c23390 38fd710970c3fe7fd37d67cba7fedb3f 846 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 331 454 4.7E-26 T 12-10-2018 IPR000014 PAS domain VAPA_1c23390 38fd710970c3fe7fd37d67cba7fedb3f 846 SUPERFAMILY SSF55785 318 445 1.33E-24 T 12-10-2018 IPR035965 PAS domain superfamily VAPA_1c23390 38fd710970c3fe7fd37d67cba7fedb3f 846 SUPERFAMILY SSF47384 589 667 1.96E-10 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 VAPA_1c23390 38fd710970c3fe7fd37d67cba7fedb3f 846 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 713 830 6.3E-13 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase VAPA_1c23390 38fd710970c3fe7fd37d67cba7fedb3f 846 Pfam PF00989 PAS fold 332 444 1.8E-17 T 12-10-2018 IPR013767 PAS fold GO:0006355 VAPA_1c23390 38fd710970c3fe7fd37d67cba7fedb3f 846 Gene3D G3DSA:3.30.565.10 669 835 3.2E-32 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_1c23390 38fd710970c3fe7fd37d67cba7fedb3f 846 SUPERFAMILY SSF55874 656 831 1.44E-29 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_1c23390 38fd710970c3fe7fd37d67cba7fedb3f 846 Gene3D G3DSA:3.30.450.20 316 473 1.7E-24 T 12-10-2018 VAPA_1c23390 38fd710970c3fe7fd37d67cba7fedb3f 846 PRINTS PR00344 Bacterial sensor protein C-terminal signature 788 806 5.4E-10 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c23390 38fd710970c3fe7fd37d67cba7fedb3f 846 PRINTS PR00344 Bacterial sensor protein C-terminal signature 759 773 5.4E-10 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c23390 38fd710970c3fe7fd37d67cba7fedb3f 846 PRINTS PR00344 Bacterial sensor protein C-terminal signature 777 787 5.4E-10 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c38930 90ccb63bedb1a1da615897bccf646aac 120 Pfam PF03960 ArsC family 8 116 1.6E-12 T 12-10-2018 IPR006660 Arsenate reductase-like VAPA_1c38930 90ccb63bedb1a1da615897bccf646aac 120 Gene3D G3DSA:3.40.30.10 4 119 1.1E-41 T 12-10-2018 VAPA_1c38930 90ccb63bedb1a1da615897bccf646aac 120 TIGRFAM TIGR01617 arsC_related: transcriptional regulator, Spx/MgsR family 6 114 5.8E-26 T 12-10-2018 IPR006504 Transcriptional regulator Spx/MgsR VAPA_1c38930 90ccb63bedb1a1da615897bccf646aac 120 SUPERFAMILY SSF52833 4 116 7.34E-32 T 12-10-2018 IPR036249 Thioredoxin-like superfamily VAPA_1c03360 1b2f9115ba83f599b17db026f5d2a50f 254 SUPERFAMILY SSF48008 99 236 2.62E-24 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal VAPA_1c03360 1b2f9115ba83f599b17db026f5d2a50f 254 Gene3D G3DSA:1.20.120.530 98 239 6.7E-24 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal VAPA_1c03360 1b2f9115ba83f599b17db026f5d2a50f 254 SMART SM00895 103 229 1.0E-14 T 12-10-2018 IPR011711 GntR, C-terminal VAPA_1c03360 1b2f9115ba83f599b17db026f5d2a50f 254 Gene3D G3DSA:1.10.10.10 29 93 7.7E-19 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c03360 1b2f9115ba83f599b17db026f5d2a50f 254 Pfam PF07729 FCD domain 103 228 1.0E-17 T 12-10-2018 IPR011711 GntR, C-terminal VAPA_1c03360 1b2f9115ba83f599b17db026f5d2a50f 254 SUPERFAMILY SSF46785 30 97 5.46E-18 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c03360 1b2f9115ba83f599b17db026f5d2a50f 254 Pfam PF00392 Bacterial regulatory proteins, gntR family 32 93 8.6E-17 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_1c03360 1b2f9115ba83f599b17db026f5d2a50f 254 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 53 64 6.0E-5 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 VAPA_1c03360 1b2f9115ba83f599b17db026f5d2a50f 254 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 64 83 6.0E-5 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 VAPA_1c03360 1b2f9115ba83f599b17db026f5d2a50f 254 SMART SM00345 35 93 2.5E-14 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_1c03360 1b2f9115ba83f599b17db026f5d2a50f 254 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 67 83 5.2E-6 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_1c03360 1b2f9115ba83f599b17db026f5d2a50f 254 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 53 67 5.2E-6 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_1c51780 70d16e6c9a95416df4505080730475ad 191 SMART SM00195 36 171 6.8E-4 T 12-10-2018 IPR020422 Dual specificity protein phosphatase domain GO:0006470|GO:0008138 VAPA_1c51780 70d16e6c9a95416df4505080730475ad 191 ProSitePatterns PS00383 Tyrosine specific protein phosphatases active site. 119 129 - T 12-10-2018 IPR016130 Protein-tyrosine phosphatase, active site GO:0004725|GO:0016311 VAPA_1c51780 70d16e6c9a95416df4505080730475ad 191 SUPERFAMILY SSF52799 34 153 1.63E-27 T 12-10-2018 IPR029021 Protein-tyrosine phosphatase-like VAPA_1c51780 70d16e6c9a95416df4505080730475ad 191 Pfam PF03162 Tyrosine phosphatase family 36 136 4.4E-10 T 12-10-2018 IPR004861 Atypical dual-specificity phosphatase Siw14-like VAPA_1c51780 70d16e6c9a95416df4505080730475ad 191 Gene3D G3DSA:3.90.190.10 23 184 4.0E-41 T 12-10-2018 IPR029021 Protein-tyrosine phosphatase-like VAPA_1c37240 05573497483b9888a06fe5e2d537d86f 304 Gene3D G3DSA:3.40.190.10 138 233 8.2E-94 T 12-10-2018 VAPA_1c37240 05573497483b9888a06fe5e2d537d86f 304 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 45 273 2.4E-45 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF VAPA_1c37240 05573497483b9888a06fe5e2d537d86f 304 SMART SM00062 44 276 1.5E-51 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF VAPA_1c37240 05573497483b9888a06fe5e2d537d86f 304 Gene3D G3DSA:3.40.190.10 34 279 8.2E-94 T 12-10-2018 VAPA_1c37240 05573497483b9888a06fe5e2d537d86f 304 SUPERFAMILY SSF53850 15 277 1.12E-58 T 12-10-2018 VAPA_1c15010 83b8f19aa813c8210ffaf8a23f8e3adf 179 Gene3D G3DSA:3.30.2010.10 72 159 1.7E-6 T 12-10-2018 VAPA_1c15010 83b8f19aa813c8210ffaf8a23f8e3adf 179 Pfam PF01863 Protein of unknown function DUF45 90 147 9.2E-11 T 12-10-2018 IPR002725 Protein of unknown function DUF45 VAPA_1c41990 256c37f2c38976c57a3d607bc73df0f0 184 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 147 164 1.9E-7 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 VAPA_1c41990 256c37f2c38976c57a3d607bc73df0f0 184 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 164 184 1.9E-7 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 VAPA_1c41990 256c37f2c38976c57a3d607bc73df0f0 184 Gene3D G3DSA:3.40.50.2300 9 127 5.3E-24 T 12-10-2018 VAPA_1c41990 256c37f2c38976c57a3d607bc73df0f0 184 Pfam PF02954 Bacterial regulatory protein, Fis family 142 180 4.9E-12 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 VAPA_1c41990 256c37f2c38976c57a3d607bc73df0f0 184 SUPERFAMILY SSF46689 128 180 1.64E-13 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 VAPA_1c41990 256c37f2c38976c57a3d607bc73df0f0 184 Gene3D G3DSA:1.10.10.60 128 182 2.7E-19 T 12-10-2018 VAPA_1c41990 256c37f2c38976c57a3d607bc73df0f0 184 SUPERFAMILY SSF52172 10 135 3.13E-25 T 12-10-2018 IPR011006 CheY-like superfamily VAPA_1c41990 256c37f2c38976c57a3d607bc73df0f0 184 SMART SM00448 9 123 2.9E-19 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_1c41990 256c37f2c38976c57a3d607bc73df0f0 184 Pfam PF00072 Response regulator receiver domain 12 122 1.4E-19 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_2c03180 56e0a6e68ba3ebc1b14bd0d9367fff1c 446 Pfam PF09937 Uncharacterized protein conserved in bacteria (DUF2169) 21 406 1.7E-74 T 12-10-2018 IPR018683 Domain of unknown function DUF2169 VAPA_1c01740 c8b1d908f81bffc7057bff10cec0fb42 443 SUPERFAMILY SSF55961 139 386 5.22E-49 T 12-10-2018 VAPA_1c01740 c8b1d908f81bffc7057bff10cec0fb42 443 Pfam PF00355 Rieske [2Fe-2S] domain 27 109 1.5E-17 T 12-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 VAPA_1c01740 c8b1d908f81bffc7057bff10cec0fb42 443 ProSitePatterns PS00570 Bacterial ring hydroxylating dioxygenases alpha-subunit signature. 69 91 - T 12-10-2018 IPR015881 Aromatic-ring-hydroxylating dioxygenase, 2Fe-2S-binding site GO:0005506|GO:0051537|GO:0055114 VAPA_1c01740 c8b1d908f81bffc7057bff10cec0fb42 443 SUPERFAMILY SSF50022 21 137 9.95E-33 T 12-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 VAPA_1c01740 c8b1d908f81bffc7057bff10cec0fb42 443 Gene3D G3DSA:2.102.10.10 23 154 9.4E-35 T 12-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 VAPA_1c36640 3d06750223134bfdc1c3713f29dc61ca 311 Gene3D G3DSA:1.10.10.10 12 100 8.6E-18 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c36640 3d06750223134bfdc1c3713f29dc61ca 311 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 15 73 2.9E-17 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c36640 3d06750223134bfdc1c3713f29dc61ca 311 Gene3D G3DSA:3.40.190.10 104 293 2.1E-21 T 12-10-2018 VAPA_1c36640 3d06750223134bfdc1c3713f29dc61ca 311 Gene3D G3DSA:3.40.190.10 178 282 2.1E-21 T 12-10-2018 VAPA_1c36640 3d06750223134bfdc1c3713f29dc61ca 311 SUPERFAMILY SSF46785 11 114 1.46E-19 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c36640 3d06750223134bfdc1c3713f29dc61ca 311 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 51 7.7E-5 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c36640 3d06750223134bfdc1c3713f29dc61ca 311 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 51 62 7.7E-5 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c36640 3d06750223134bfdc1c3713f29dc61ca 311 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 41 7.7E-5 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c36640 3d06750223134bfdc1c3713f29dc61ca 311 Pfam PF03466 LysR substrate binding domain 99 309 7.8E-15 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_1c36640 3d06750223134bfdc1c3713f29dc61ca 311 SUPERFAMILY SSF53850 100 308 1.77E-18 T 12-10-2018 VAPA_2c07260 338a1529869c7eea66540f29a61c2e4e 280 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 37 255 2.6E-47 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF VAPA_2c07260 338a1529869c7eea66540f29a61c2e4e 280 SMART SM00062 36 257 9.1E-48 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF VAPA_2c07260 338a1529869c7eea66540f29a61c2e4e 280 SUPERFAMILY SSF53850 8 256 2.27E-53 T 12-10-2018 VAPA_2c07260 338a1529869c7eea66540f29a61c2e4e 280 Gene3D G3DSA:3.40.190.10 121 219 1.0E-49 T 12-10-2018 VAPA_2c07260 338a1529869c7eea66540f29a61c2e4e 280 Gene3D G3DSA:3.40.190.10 34 253 1.0E-49 T 12-10-2018 VAPA_1c21030 31b08f45d96e5c82312261829fb186b5 221 SUPERFAMILY SSF53271 6 213 4.85E-53 T 12-10-2018 IPR029057 Phosphoribosyltransferase-like VAPA_1c21030 31b08f45d96e5c82312261829fb186b5 221 Gene3D G3DSA:3.40.50.2020 6 207 3.4E-76 T 12-10-2018 VAPA_1c21030 31b08f45d96e5c82312261829fb186b5 221 Pfam PF00156 Phosphoribosyl transferase domain 12 198 2.8E-24 T 12-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 VAPA_1c21030 31b08f45d96e5c82312261829fb186b5 221 Gene3D G3DSA:3.30.1310.20 57 119 3.4E-76 T 12-10-2018 VAPA_1c15720 464646dd987fe827f1acaccaf43f620d 318 Gene3D G3DSA:3.40.50.300 77 248 9.3E-36 T 12-10-2018 VAPA_1c15720 464646dd987fe827f1acaccaf43f620d 318 TIGRFAM TIGR00157 TIGR00157: ribosome small subunit-dependent GTPase A 54 309 1.3E-51 T 12-10-2018 IPR004881 Ribosome biogenesis GTPase RsgA GO:0003924|GO:0005525 VAPA_1c15720 464646dd987fe827f1acaccaf43f620d 318 Pfam PF03193 RsgA GTPase 73 248 2.6E-41 T 12-10-2018 IPR010914 RsgA GTPase domain GO:0003924|GO:0005525 VAPA_1c15720 464646dd987fe827f1acaccaf43f620d 318 SUPERFAMILY SSF50249 20 77 2.06E-6 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold VAPA_1c15720 464646dd987fe827f1acaccaf43f620d 318 Hamap MF_01820 Small ribosomal subunit biogenesis GTPase RsgA [rsgA]. 20 317 31.24 T 12-10-2018 IPR004881 Ribosome biogenesis GTPase RsgA GO:0003924|GO:0005525 VAPA_1c15720 464646dd987fe827f1acaccaf43f620d 318 SUPERFAMILY SSF52540 89 305 1.68E-41 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c15720 464646dd987fe827f1acaccaf43f620d 318 Gene3D G3DSA:1.10.40.50 249 318 5.3E-14 T 12-10-2018 VAPA_1c15720 464646dd987fe827f1acaccaf43f620d 318 Gene3D G3DSA:2.40.50.140 19 74 1.6E-16 T 12-10-2018 VAPA_1c39520 2b6503efee26479a2d01fa45dbd1812e 167 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 38 46 - T 12-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 VAPA_1c39520 2b6503efee26479a2d01fa45dbd1812e 167 Pfam PF01799 [2Fe-2S] binding domain 72 145 3.2E-24 T 12-10-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 VAPA_1c39520 2b6503efee26479a2d01fa45dbd1812e 167 SUPERFAMILY SSF47741 83 149 1.31E-27 T 12-10-2018 IPR036884 [2Fe-2S]-binding domain superfamily VAPA_1c39520 2b6503efee26479a2d01fa45dbd1812e 167 Gene3D G3DSA:3.10.20.30 1 75 3.8E-26 T 12-10-2018 IPR012675 Beta-grasp domain superfamily VAPA_1c39520 2b6503efee26479a2d01fa45dbd1812e 167 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 5 58 1.5E-7 T 12-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 VAPA_1c39520 2b6503efee26479a2d01fa45dbd1812e 167 Gene3D G3DSA:1.10.150.120 76 155 3.0E-24 T 12-10-2018 VAPA_1c39520 2b6503efee26479a2d01fa45dbd1812e 167 SUPERFAMILY SSF54292 2 76 2.23E-25 T 12-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 VAPA_1c53270 e209dff5413c4b1ddabf8ed06be5a85f 342 Gene3D G3DSA:3.40.190.10 35 326 1.5E-41 T 12-10-2018 VAPA_1c53270 e209dff5413c4b1ddabf8ed06be5a85f 342 SUPERFAMILY SSF53850 27 278 1.97E-19 T 12-10-2018 VAPA_1c53270 e209dff5413c4b1ddabf8ed06be5a85f 342 Gene3D G3DSA:3.40.190.10 112 210 1.5E-41 T 12-10-2018 VAPA_1c53270 e209dff5413c4b1ddabf8ed06be5a85f 342 Pfam PF09084 NMT1/THI5 like 40 242 1.8E-20 T 12-10-2018 IPR015168 SsuA/THI5-like VAPA_1c11040 2e374242c174a6a9eeb055e197001d80 583 SUPERFAMILY SSF52016 381 570 2.59E-55 T 12-10-2018 VAPA_1c11040 2e374242c174a6a9eeb055e197001d80 583 Gene3D G3DSA:3.50.30.80 381 535 5.1E-48 T 12-10-2018 VAPA_1c11040 2e374242c174a6a9eeb055e197001d80 583 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 126 136 - T 12-10-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 VAPA_1c11040 2e374242c174a6a9eeb055e197001d80 583 SUPERFAMILY SSF143975 6 380 3.27E-121 T 12-10-2018 IPR037237 IlvD/EDD, N-terminal domain KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 VAPA_1c11040 2e374242c174a6a9eeb055e197001d80 583 Pfam PF00920 Dehydratase family 43 565 2.3E-172 T 12-10-2018 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 VAPA_1c31860 5964ba497253897c18911b46276e3d14 1172 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 297 743 1.1E-170 T 12-10-2018 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 VAPA_1c31860 5964ba497253897c18911b46276e3d14 1172 Pfam PF02811 PHP domain 4 172 4.3E-36 T 12-10-2018 IPR004013 PHP domain GO:0003824 VAPA_1c31860 5964ba497253897c18911b46276e3d14 1172 SUPERFAMILY SSF89550 1 262 8.44E-12 T 12-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 VAPA_1c31860 5964ba497253897c18911b46276e3d14 1172 Gene3D G3DSA:1.10.10.1600 438 530 4.4E-25 T 12-10-2018 VAPA_1c31860 5964ba497253897c18911b46276e3d14 1172 Gene3D G3DSA:3.20.20.140 1 269 7.5E-80 T 12-10-2018 VAPA_1c31860 5964ba497253897c18911b46276e3d14 1172 TIGRFAM TIGR00594 polc: DNA polymerase III, alpha subunit 2 1035 0.0 T 12-10-2018 IPR004805 DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 VAPA_1c31860 5964ba497253897c18911b46276e3d14 1172 Pfam PF14579 Helix-hairpin-helix motif 821 910 4.5E-26 T 12-10-2018 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 VAPA_1c31860 5964ba497253897c18911b46276e3d14 1172 SMART SM00481 3 70 2.3E-21 T 12-10-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal VAPA_1c28990 c3c8ef8d148da9a95878a5d42aaee6da 479 Pfam PF00929 Exonuclease 6 187 3.5E-23 T 12-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III VAPA_1c28990 c3c8ef8d148da9a95878a5d42aaee6da 479 Pfam PF08411 Exonuclease C-terminal 207 473 4.0E-89 T 12-10-2018 IPR013620 Exodeoxyribonuclease I, C-terminal GO:0006281|GO:0008852 VAPA_1c28990 c3c8ef8d148da9a95878a5d42aaee6da 479 Gene3D G3DSA:3.30.420.10 1 195 3.9E-72 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 VAPA_1c28990 c3c8ef8d148da9a95878a5d42aaee6da 479 PIRSF PIRSF000977 1 479 3.3E-201 T 12-10-2018 IPR023607 Exodeoxyribonuclease I GO:0004529 VAPA_1c28990 c3c8ef8d148da9a95878a5d42aaee6da 479 Gene3D G3DSA:2.30.30.450 219 353 9.9E-44 T 12-10-2018 IPR038649 Exonuclease I, SH3-like domain superfamily VAPA_1c28990 c3c8ef8d148da9a95878a5d42aaee6da 479 SUPERFAMILY SSF53098 4 465 1.2E-119 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily VAPA_1c28990 c3c8ef8d148da9a95878a5d42aaee6da 479 Gene3D G3DSA:1.20.1280.70 358 418 1.4E-23 T 12-10-2018 VAPA_1c05210 2b26ba24ec6614e7927042948277227d 387 SUPERFAMILY SSF47203 233 382 9.34E-48 T 12-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 VAPA_1c05210 2b26ba24ec6614e7927042948277227d 387 Gene3D G3DSA:1.20.140.10 240 384 3.9E-45 T 12-10-2018 VAPA_1c05210 2b26ba24ec6614e7927042948277227d 387 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 125 137 - T 12-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 VAPA_1c05210 2b26ba24ec6614e7927042948277227d 387 Gene3D G3DSA:2.40.110.10 122 239 3.1E-39 T 12-10-2018 VAPA_1c05210 2b26ba24ec6614e7927042948277227d 387 PIRSF PIRSF016578 4 79 0.67 T 12-10-2018 VAPA_1c05210 2b26ba24ec6614e7927042948277227d 387 PIRSF PIRSF016578 132 384 8.8E-11 T 12-10-2018 VAPA_1c05210 2b26ba24ec6614e7927042948277227d 387 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 341 360 - T 12-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 VAPA_1c05210 2b26ba24ec6614e7927042948277227d 387 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 234 382 7.5E-44 T 12-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 VAPA_1c05210 2b26ba24ec6614e7927042948277227d 387 Gene3D G3DSA:1.10.540.10 1 121 4.7E-38 T 12-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 VAPA_1c05210 2b26ba24ec6614e7927042948277227d 387 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 123 219 7.4E-27 T 12-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 VAPA_1c05210 2b26ba24ec6614e7927042948277227d 387 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 9 119 9.0E-35 T 12-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 VAPA_1c05210 2b26ba24ec6614e7927042948277227d 387 SUPERFAMILY SSF56645 5 245 8.9E-84 T 12-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 VAPA_1c45360 8773e9de457f18bcef64f7cad44b08a7 244 Pfam PF12146 Serine aminopeptidase, S33 47 228 4.3E-16 T 12-10-2018 IPR022742 Serine aminopeptidase, S33 VAPA_1c45360 8773e9de457f18bcef64f7cad44b08a7 244 PRINTS PR00111 Alpha/beta hydrolase fold signature 186 200 1.0E-6 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 VAPA_1c45360 8773e9de457f18bcef64f7cad44b08a7 244 PRINTS PR00111 Alpha/beta hydrolase fold signature 84 97 1.0E-6 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 VAPA_1c45360 8773e9de457f18bcef64f7cad44b08a7 244 PRINTS PR00111 Alpha/beta hydrolase fold signature 70 83 1.0E-6 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 VAPA_1c45360 8773e9de457f18bcef64f7cad44b08a7 244 Gene3D G3DSA:3.40.50.1820 5 243 2.1E-47 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c45360 8773e9de457f18bcef64f7cad44b08a7 244 SUPERFAMILY SSF53474 13 241 9.92E-49 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c19560 d17bad2dd64e065744b3803c9dff1e27 327 PIRSF PIRSF017082 1 326 1.3E-76 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c19560 d17bad2dd64e065744b3803c9dff1e27 327 Gene3D G3DSA:3.40.190.10 128 251 2.4E-104 T 12-10-2018 VAPA_1c19560 d17bad2dd64e065744b3803c9dff1e27 327 Gene3D G3DSA:3.40.190.150 31 316 2.4E-104 T 12-10-2018 VAPA_1c19560 d17bad2dd64e065744b3803c9dff1e27 327 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 50 322 3.1E-85 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c19560 d17bad2dd64e065744b3803c9dff1e27 327 SUPERFAMILY SSF53850 116 290 5.26E-13 T 12-10-2018 VAPA_2c08460 046ea74d9124f45acc75632004a0944d 340 SUPERFAMILY SSF53474 46 336 5.3E-54 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_2c08460 046ea74d9124f45acc75632004a0944d 340 Pfam PF00561 alpha/beta hydrolase fold 69 199 2.7E-18 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 VAPA_2c08460 046ea74d9124f45acc75632004a0944d 340 PRINTS PR00412 Epoxide hydrolase signature 142 155 2.1E-15 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 VAPA_2c08460 046ea74d9124f45acc75632004a0944d 340 PRINTS PR00412 Epoxide hydrolase signature 281 297 2.1E-15 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 VAPA_2c08460 046ea74d9124f45acc75632004a0944d 340 PRINTS PR00412 Epoxide hydrolase signature 156 169 2.1E-15 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 VAPA_2c08460 046ea74d9124f45acc75632004a0944d 340 PRINTS PR00412 Epoxide hydrolase signature 315 337 2.1E-15 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 VAPA_2c08460 046ea74d9124f45acc75632004a0944d 340 PRINTS PR00412 Epoxide hydrolase signature 74 92 2.1E-15 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 VAPA_2c08460 046ea74d9124f45acc75632004a0944d 340 PRINTS PR00412 Epoxide hydrolase signature 94 109 2.1E-15 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 VAPA_2c08460 046ea74d9124f45acc75632004a0944d 340 Gene3D G3DSA:3.40.50.1820 39 339 1.4E-81 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_2c08030 ff62220a35053f063740aae486e16790 99 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 37 45 - T 12-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 VAPA_2c08030 ff62220a35053f063740aae486e16790 99 SUPERFAMILY SSF54292 3 94 6.59E-21 T 12-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 VAPA_2c08030 ff62220a35053f063740aae486e16790 99 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 13 84 2.4E-12 T 12-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 VAPA_2c08030 ff62220a35053f063740aae486e16790 99 Gene3D G3DSA:3.10.20.30 2 96 8.4E-22 T 12-10-2018 IPR012675 Beta-grasp domain superfamily VAPA_2c07050 4b86a119eab856773509718bcc04cc0d 586 Pfam PF00890 FAD binding domain 9 547 2.3E-106 T 12-10-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 VAPA_2c07050 4b86a119eab856773509718bcc04cc0d 586 SUPERFAMILY SSF56425 341 506 6.98E-33 T 12-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 VAPA_2c07050 4b86a119eab856773509718bcc04cc0d 586 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 9 31 2.4E-8 T 12-10-2018 VAPA_2c07050 4b86a119eab856773509718bcc04cc0d 586 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 422 442 2.4E-8 T 12-10-2018 VAPA_2c07050 4b86a119eab856773509718bcc04cc0d 586 SUPERFAMILY SSF51905 4 566 4.75E-41 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_2c07050 4b86a119eab856773509718bcc04cc0d 586 Gene3D G3DSA:3.50.50.60 8 558 4.6E-139 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_2c07050 4b86a119eab856773509718bcc04cc0d 586 Gene3D G3DSA:3.90.700.10 343 495 4.6E-139 T 12-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 VAPA_1c24710 f4b16dc1117983d40026fea178583eb2 196 TIGRFAM TIGR00615 recR: recombination protein RecR 5 196 1.4E-68 T 12-10-2018 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 VAPA_1c24710 f4b16dc1117983d40026fea178583eb2 196 Hamap MF_00017 Recombination protein RecR [recR]. 1 196 94.97 T 12-10-2018 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 VAPA_1c24710 f4b16dc1117983d40026fea178583eb2 196 Pfam PF13662 Toprim domain 81 171 4.6E-23 T 12-10-2018 IPR006171 TOPRIM domain VAPA_1c24710 f4b16dc1117983d40026fea178583eb2 196 SUPERFAMILY SSF111304 5 196 1.7E-70 T 12-10-2018 IPR023627 Recombination protein RecR VAPA_1c24710 f4b16dc1117983d40026fea178583eb2 196 Gene3D G3DSA:3.40.1360.10 77 196 2.4E-40 T 12-10-2018 VAPA_1c24710 f4b16dc1117983d40026fea178583eb2 196 ProSitePatterns PS01300 RecR protein signature. 57 78 - T 12-10-2018 IPR015967 Recombination protein RecR, conserved site GO:0006281|GO:0006310 VAPA_1c24710 f4b16dc1117983d40026fea178583eb2 196 SMART SM00493 80 165 8.2E-12 T 12-10-2018 IPR006171 TOPRIM domain VAPA_1c24710 f4b16dc1117983d40026fea178583eb2 196 Gene3D G3DSA:1.10.8.420 1 52 8.6E-18 T 12-10-2018 VAPA_1c24710 f4b16dc1117983d40026fea178583eb2 196 Pfam PF02132 RecR protein 40 78 1.2E-14 T 12-10-2018 IPR023628 Recombination protein RecR, C4-type zinc finger VAPA_1c17180 691958b3389ac2b49dd2912bc41e3ee6 222 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 102 115 9.7E-5 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 VAPA_1c17180 691958b3389ac2b49dd2912bc41e3ee6 222 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 6 17 9.7E-5 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 VAPA_1c17180 691958b3389ac2b49dd2912bc41e3ee6 222 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 133 149 9.7E-5 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 VAPA_1c17180 691958b3389ac2b49dd2912bc41e3ee6 222 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 90 187 1.6E-8 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 VAPA_1c17180 691958b3389ac2b49dd2912bc41e3ee6 222 SUPERFAMILY SSF56784 6 219 5.15E-55 T 12-10-2018 IPR036412 HAD-like superfamily VAPA_1c17180 691958b3389ac2b49dd2912bc41e3ee6 222 Gene3D G3DSA:3.40.50.1000 9 205 8.5E-51 T 12-10-2018 IPR023214 HAD superfamily VAPA_1c17180 691958b3389ac2b49dd2912bc41e3ee6 222 TIGRFAM TIGR01449 PGP_bact: phosphoglycolate phosphatase, bacterial 9 202 9.4E-51 T 12-10-2018 IPR006346 2-phosphoglycolate phosphatase-like, prokaryotic GO:0016791 KEGG: 00630+3.1.3.18|MetaCyc: PWY-181 VAPA_1c17180 691958b3389ac2b49dd2912bc41e3ee6 222 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 104 183 4.3E-10 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 VAPA_1c17180 691958b3389ac2b49dd2912bc41e3ee6 222 Gene3D G3DSA:1.10.150.240 21 87 8.5E-51 T 12-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 VAPA_1c17180 691958b3389ac2b49dd2912bc41e3ee6 222 Pfam PF13419 Haloacid dehalogenase-like hydrolase 9 188 3.5E-31 T 12-10-2018 VAPA_1c36550 6f6b6b3758e5a7e58c783010c547fbca 301 Pfam PF03466 LysR substrate binding domain 89 292 5.5E-42 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_1c36550 6f6b6b3758e5a7e58c783010c547fbca 301 Gene3D G3DSA:3.40.190.290 92 298 7.5E-42 T 12-10-2018 VAPA_1c36550 6f6b6b3758e5a7e58c783010c547fbca 301 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 64 8.7E-17 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c36550 6f6b6b3758e5a7e58c783010c547fbca 301 SUPERFAMILY SSF53850 89 296 2.99E-42 T 12-10-2018 VAPA_1c36550 6f6b6b3758e5a7e58c783010c547fbca 301 SUPERFAMILY SSF46785 1 113 5.44E-25 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c36550 6f6b6b3758e5a7e58c783010c547fbca 301 Gene3D G3DSA:1.10.10.10 3 90 6.3E-21 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_2c00540 2b6cdcbb8451262a55a4d67f61fa0d2a 394 Pfam PF13378 Enolase C-terminal domain-like 186 385 1.0E-43 T 12-10-2018 IPR029065 Enolase C-terminal domain-like VAPA_2c00540 2b6cdcbb8451262a55a4d67f61fa0d2a 394 SMART SM00922 155 261 3.6E-9 T 12-10-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal VAPA_2c00540 2b6cdcbb8451262a55a4d67f61fa0d2a 394 Gene3D G3DSA:3.30.390.10 4 148 7.0E-207 T 12-10-2018 IPR029017 Enolase-like, N-terminal VAPA_2c00540 2b6cdcbb8451262a55a4d67f61fa0d2a 394 SUPERFAMILY SSF51604 137 392 1.27E-60 T 12-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily VAPA_2c00540 2b6cdcbb8451262a55a4d67f61fa0d2a 394 SUPERFAMILY SSF54826 47 153 3.24E-26 T 12-10-2018 VAPA_2c00540 2b6cdcbb8451262a55a4d67f61fa0d2a 394 Gene3D G3DSA:3.20.20.120 149 386 7.0E-207 T 12-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily VAPA_2c00540 2b6cdcbb8451262a55a4d67f61fa0d2a 394 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 59 149 3.5E-11 T 12-10-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain VAPA_2c00540 2b6cdcbb8451262a55a4d67f61fa0d2a 394 Hamap MF_01288 L-rhamnonate dehydratase [rhmD]. 1 394 78.382 T 12-10-2018 IPR023444 L-rhamnonate dehydratase GO:0050032 KEGG: 00051+4.2.1.90|MetaCyc: PWY-6713|MetaCyc: PWY-6714 VAPA_1c25170 49d76db630b8fbc1337b0675c98a1fd3 251 Gene3D G3DSA:2.30.210.20 5 64 2.8E-16 T 12-10-2018 VAPA_1c25170 49d76db630b8fbc1337b0675c98a1fd3 251 SUPERFAMILY SSF55729 3 238 9.53E-81 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase VAPA_1c25170 49d76db630b8fbc1337b0675c98a1fd3 251 TIGRFAM TIGR00667 aat: leucyl/phenylalanyl-tRNA--protein transferase 37 226 7.9E-49 T 12-10-2018 IPR004616 Leucyl/phenylalanyl-tRNA-protein transferase GO:0008914|GO:0030163 MetaCyc: PWY-7801 VAPA_1c25170 49d76db630b8fbc1337b0675c98a1fd3 251 Pfam PF03588 Leucyl/phenylalanyl-tRNA protein transferase 39 212 1.2E-68 T 12-10-2018 IPR004616 Leucyl/phenylalanyl-tRNA-protein transferase GO:0008914|GO:0030163 MetaCyc: PWY-7801 VAPA_1c25170 49d76db630b8fbc1337b0675c98a1fd3 251 Gene3D G3DSA:3.40.630.70 65 245 6.2E-60 T 12-10-2018 VAPA_1c25170 49d76db630b8fbc1337b0675c98a1fd3 251 Hamap MF_00688 Leucyl/phenylalanyl-tRNA--protein transferase [aat]. 1 251 91.082 T 12-10-2018 IPR004616 Leucyl/phenylalanyl-tRNA-protein transferase GO:0008914|GO:0030163 MetaCyc: PWY-7801 VAPA_1c52520 66be0cd17e66e59f4cb469c3c03c6f07 122 Gene3D G3DSA:2.40.150.20 1 122 4.6E-52 T 12-10-2018 IPR036853 Ribosomal protein L14 superfamily GO:0003735|GO:0005840|GO:0006412 VAPA_1c52520 66be0cd17e66e59f4cb469c3c03c6f07 122 TIGRFAM TIGR01067 rplN_bact: ribosomal protein uL14 1 122 3.4E-56 T 12-10-2018 IPR005745 Ribosomal protein L14P, bacterial-type GO:0003735|GO:0006412|GO:0015934 VAPA_1c52520 66be0cd17e66e59f4cb469c3c03c6f07 122 Hamap MF_01367 50S ribosomal protein L14 [rplN]. 1 122 26.025 T 12-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 VAPA_1c52520 66be0cd17e66e59f4cb469c3c03c6f07 122 ProSitePatterns PS00049 Ribosomal protein L14 signature. 60 86 - T 12-10-2018 IPR019972 Ribosomal protein L14P, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VAPA_1c52520 66be0cd17e66e59f4cb469c3c03c6f07 122 SMART SM01374 1 122 2.2E-82 T 12-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 VAPA_1c52520 66be0cd17e66e59f4cb469c3c03c6f07 122 Pfam PF00238 Ribosomal protein L14p/L23e 1 122 4.3E-53 T 12-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 VAPA_1c52520 66be0cd17e66e59f4cb469c3c03c6f07 122 SUPERFAMILY SSF50193 1 122 2.22E-49 T 12-10-2018 IPR036853 Ribosomal protein L14 superfamily GO:0003735|GO:0005840|GO:0006412 VAPA_1c28360 865402be465877fffdacbd19446554c4 1300 SMART SM00487 27 222 2.0E-25 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain VAPA_1c28360 865402be465877fffdacbd19446554c4 1300 Gene3D G3DSA:1.20.120.1080 416 518 2.0E-19 T 12-10-2018 VAPA_1c28360 865402be465877fffdacbd19446554c4 1300 Pfam PF04408 Helicase associated domain (HA2) 434 510 1.7E-15 T 12-10-2018 IPR007502 Helicase-associated domain GO:0004386 VAPA_1c28360 865402be465877fffdacbd19446554c4 1300 SMART SM00847 431 521 1.2E-30 T 12-10-2018 IPR007502 Helicase-associated domain GO:0004386 VAPA_1c28360 865402be465877fffdacbd19446554c4 1300 Gene3D G3DSA:3.40.50.300 216 387 3.3E-54 T 12-10-2018 VAPA_1c28360 865402be465877fffdacbd19446554c4 1300 TIGRFAM TIGR01967 DEAH_box_HrpA: RNA helicase HrpA 22 1296 0.0 T 12-10-2018 IPR010222 RNA helicase HrpA GO:0004004 VAPA_1c28360 865402be465877fffdacbd19446554c4 1300 SMART SM00382 44 337 4.1E-6 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c28360 865402be465877fffdacbd19446554c4 1300 Gene3D G3DSA:3.40.50.300 19 215 2.1E-71 T 12-10-2018 VAPA_1c28360 865402be465877fffdacbd19446554c4 1300 Pfam PF11898 Domain of unknown function (DUF3418) 681 1297 3.3E-209 T 12-10-2018 IPR024590 RNA helicase HrpA, C-terminal VAPA_1c28360 865402be465877fffdacbd19446554c4 1300 SMART SM00490 270 371 1.9E-14 T 12-10-2018 IPR001650 Helicase, C-terminal VAPA_1c28360 865402be465877fffdacbd19446554c4 1300 Pfam PF07717 Oligonucleotide/oligosaccharide-binding (OB)-fold 590 667 1.6E-12 T 12-10-2018 IPR011709 Domain of unknown function DUF1605 VAPA_1c28360 865402be465877fffdacbd19446554c4 1300 Pfam PF00270 DEAD/DEAH box helicase 37 192 1.3E-6 T 12-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 VAPA_1c28360 865402be465877fffdacbd19446554c4 1300 SUPERFAMILY SSF52540 26 529 1.29E-97 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c28360 865402be465877fffdacbd19446554c4 1300 Pfam PF00271 Helicase conserved C-terminal domain 249 370 1.7E-9 T 12-10-2018 IPR001650 Helicase, C-terminal VAPA_2c03690 64419aae035c8e7069e59cc037a90ba5 310 SUPERFAMILY SSF51197 10 307 2.47E-44 T 12-10-2018 VAPA_2c03690 64419aae035c8e7069e59cc037a90ba5 310 Pfam PF05721 Phytanoyl-CoA dioxygenase (PhyH) 16 264 1.3E-23 T 12-10-2018 IPR008775 Phytanoyl-CoA dioxygenase VAPA_1c38240 c61a867feca54a671a9e6734bbc2de5c 353 Pfam PF13343 Bacterial extracellular solute-binding protein 84 310 1.1E-17 T 12-10-2018 VAPA_1c38240 c61a867feca54a671a9e6734bbc2de5c 353 Gene3D G3DSA:3.40.190.10 132 346 2.6E-117 T 12-10-2018 VAPA_1c38240 c61a867feca54a671a9e6734bbc2de5c 353 Gene3D G3DSA:3.40.190.10 39 312 2.6E-117 T 12-10-2018 VAPA_1c38240 c61a867feca54a671a9e6734bbc2de5c 353 SUPERFAMILY SSF53850 35 351 4.74E-69 T 12-10-2018 VAPA_1c38240 c61a867feca54a671a9e6734bbc2de5c 353 PIRSF PIRSF002825 5 353 4.0E-80 T 12-10-2018 IPR026045 Ferric binding protein VAPA_2c08360 5533a392649765f3367ddbd96c8cfbac 313 Gene3D G3DSA:1.10.10.10 3 92 1.6E-21 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_2c08360 5533a392649765f3367ddbd96c8cfbac 313 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 64 2.3E-18 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_2c08360 5533a392649765f3367ddbd96c8cfbac 313 SUPERFAMILY SSF53850 92 298 1.09E-37 T 12-10-2018 VAPA_2c08360 5533a392649765f3367ddbd96c8cfbac 313 Pfam PF03466 LysR substrate binding domain 90 295 3.1E-38 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_2c08360 5533a392649765f3367ddbd96c8cfbac 313 Gene3D G3DSA:3.40.190.290 93 301 1.3E-36 T 12-10-2018 VAPA_2c08360 5533a392649765f3367ddbd96c8cfbac 313 SUPERFAMILY SSF46785 8 112 1.03E-18 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c04590 75d4eb3ea583539b116be723b1993e35 143 SUPERFAMILY SSF51316 5 141 2.82E-39 T 12-10-2018 IPR011057 Mss4-like superfamily VAPA_1c04590 75d4eb3ea583539b116be723b1993e35 143 Gene3D G3DSA:3.90.1590.10 2 123 6.4E-15 T 12-10-2018 VAPA_1c04590 75d4eb3ea583539b116be723b1993e35 143 Pfam PF04828 Glutathione-dependent formaldehyde-activating enzyme 34 120 3.5E-16 T 12-10-2018 IPR006913 Glutathione-dependent formaldehyde-activating enzyme/centromere protein V GO:0016846 KEGG: 00680+4.4.1.22|MetaCyc: PWY-1801 VAPA_2c10650 c1fcd1c150c60e953e0c816f0da33fb8 306 Gene3D G3DSA:1.10.10.10 2 85 2.0E-16 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_2c10650 c1fcd1c150c60e953e0c816f0da33fb8 306 Gene3D G3DSA:3.40.190.10 114 277 5.2E-11 T 12-10-2018 VAPA_2c10650 c1fcd1c150c60e953e0c816f0da33fb8 306 Gene3D G3DSA:3.40.190.10 168 268 5.2E-11 T 12-10-2018 VAPA_2c10650 c1fcd1c150c60e953e0c816f0da33fb8 306 SUPERFAMILY SSF46785 5 89 4.79E-16 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_2c10650 c1fcd1c150c60e953e0c816f0da33fb8 306 SUPERFAMILY SSF53850 93 293 1.01E-25 T 12-10-2018 VAPA_2c10650 c1fcd1c150c60e953e0c816f0da33fb8 306 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 65 2.6E-16 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_2c10650 c1fcd1c150c60e953e0c816f0da33fb8 306 Pfam PF03466 LysR substrate binding domain 91 292 3.9E-23 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_1c52550 ba95b37fd791bfe3d9be74511fffe15e 286 TIGRFAM TIGR01474 ubiA_proteo: 4-hydroxybenzoate polyprenyl transferase 8 283 1.6E-91 T 12-10-2018 IPR006370 4-hydroxybenzoate polyprenyltransferase-like GO:0004659|GO:0016021 Reactome: R-HSA-1268020|Reactome: R-HSA-2142789 VAPA_1c52550 ba95b37fd791bfe3d9be74511fffe15e 286 Pfam PF01040 UbiA prenyltransferase family 24 271 1.1E-58 T 12-10-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 VAPA_1c52550 ba95b37fd791bfe3d9be74511fffe15e 286 Hamap MF_01635 4-hydroxybenzoate octaprenyltransferase [ubiA]. 1 284 27.372 T 12-10-2018 IPR006370 4-hydroxybenzoate polyprenyltransferase-like GO:0004659|GO:0016021 Reactome: R-HSA-1268020|Reactome: R-HSA-2142789 VAPA_1c52550 ba95b37fd791bfe3d9be74511fffe15e 286 Gene3D G3DSA:1.10.357.140 22 180 4.1E-38 T 12-10-2018 VAPA_1c52550 ba95b37fd791bfe3d9be74511fffe15e 286 ProSitePatterns PS00943 UbiA prenyltransferase family signature. 63 85 - T 12-10-2018 IPR030470 UbiA prenyltransferase conserved site VAPA_1c23180 25223684247861b0b9fd5559e7f2d1ca 235 Pfam PF00929 Exonuclease 5 166 4.4E-31 T 12-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III VAPA_1c23180 25223684247861b0b9fd5559e7f2d1ca 235 SMART SM00479 3 175 1.7E-35 T 12-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III VAPA_1c23180 25223684247861b0b9fd5559e7f2d1ca 235 TIGRFAM TIGR01406 dnaQ_proteo: DNA polymerase III, epsilon subunit 3 225 5.2E-83 T 12-10-2018 IPR006309 DNA polymerase 3, epsilon subunit GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 VAPA_1c23180 25223684247861b0b9fd5559e7f2d1ca 235 SUPERFAMILY SSF53098 3 176 1.52E-49 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily VAPA_1c23180 25223684247861b0b9fd5559e7f2d1ca 235 Gene3D G3DSA:3.30.420.10 1 182 8.2E-50 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 VAPA_1c23180 25223684247861b0b9fd5559e7f2d1ca 235 TIGRFAM TIGR00573 dnaq: exonuclease, DNA polymerase III, epsilon subunit family 5 214 2.2E-57 T 12-10-2018 IPR006054 DNA polymerase III epsilon subunit, exonuclease domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 VAPA_1c54140 21d98f35f5c03faba2d4d708d39437ee 290 Pfam PF05013 N-formylglutamate amidohydrolase 22 258 8.6E-66 T 12-10-2018 IPR007709 N-formylglutamate amidohydrolase VAPA_1c54140 21d98f35f5c03faba2d4d708d39437ee 290 SUPERFAMILY SSF53187 14 286 1.85E-80 T 12-10-2018 VAPA_1c54140 21d98f35f5c03faba2d4d708d39437ee 290 Gene3D G3DSA:3.40.630.40 6 288 1.5E-90 T 12-10-2018 VAPA_1c24170 cbc68078453a0ee26da8cf111bc749e9 475 Pfam PF01425 Amidase 29 455 7.6E-94 T 12-10-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 VAPA_1c24170 cbc68078453a0ee26da8cf111bc749e9 475 ProSitePatterns PS00571 Amidases signature. 155 186 - T 12-10-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 VAPA_1c24170 cbc68078453a0ee26da8cf111bc749e9 475 SUPERFAMILY SSF75304 5 465 2.62E-114 T 12-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 VAPA_1c24170 cbc68078453a0ee26da8cf111bc749e9 475 Gene3D G3DSA:3.90.1300.10 10 465 4.0E-115 T 12-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 VAPA_1c12240 43dfc9fdb54390ca08c79dcf307afcd4 456 Hamap MF_01024 Histidinol dehydrogenase [hisD]. 11 453 40.433 T 12-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 VAPA_1c12240 43dfc9fdb54390ca08c79dcf307afcd4 456 PRINTS PR00083 Histidinol dehydrogenase signature 255 276 9.3E-58 T 12-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 VAPA_1c12240 43dfc9fdb54390ca08c79dcf307afcd4 456 PRINTS PR00083 Histidinol dehydrogenase signature 277 296 9.3E-58 T 12-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 VAPA_1c12240 43dfc9fdb54390ca08c79dcf307afcd4 456 PRINTS PR00083 Histidinol dehydrogenase signature 387 405 9.3E-58 T 12-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 VAPA_1c12240 43dfc9fdb54390ca08c79dcf307afcd4 456 PRINTS PR00083 Histidinol dehydrogenase signature 346 371 9.3E-58 T 12-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 VAPA_1c12240 43dfc9fdb54390ca08c79dcf307afcd4 456 PRINTS PR00083 Histidinol dehydrogenase signature 226 251 9.3E-58 T 12-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 VAPA_1c12240 43dfc9fdb54390ca08c79dcf307afcd4 456 PRINTS PR00083 Histidinol dehydrogenase signature 39 63 9.3E-58 T 12-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 VAPA_1c12240 43dfc9fdb54390ca08c79dcf307afcd4 456 Gene3D G3DSA:3.40.50.1980 36 257 1.7E-119 T 12-10-2018 VAPA_1c12240 43dfc9fdb54390ca08c79dcf307afcd4 456 Gene3D G3DSA:3.40.50.1980 259 375 1.7E-119 T 12-10-2018 VAPA_1c12240 43dfc9fdb54390ca08c79dcf307afcd4 456 PIRSF PIRSF000099 10 456 5.5E-149 T 12-10-2018 IPR022695 Histidinol dehydrogenase, monofunctional GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 VAPA_1c12240 43dfc9fdb54390ca08c79dcf307afcd4 456 TIGRFAM TIGR00069 hisD: histidinol dehydrogenase 39 452 5.3E-151 T 12-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 VAPA_1c12240 43dfc9fdb54390ca08c79dcf307afcd4 456 ProSitePatterns PS00611 Histidinol dehydrogenase signature. 255 287 - T 12-10-2018 IPR001692 Histidinol dehydrogenase, conserved site GO:0000105|GO:0004399|GO:0055114 KEGG: 00340+1.1.1.23 VAPA_1c12240 43dfc9fdb54390ca08c79dcf307afcd4 456 SUPERFAMILY SSF53720 33 453 1.14E-83 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 VAPA_1c12240 43dfc9fdb54390ca08c79dcf307afcd4 456 Pfam PF00815 Histidinol dehydrogenase 31 453 1.3E-160 T 12-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 VAPA_1c05900 93a281c7f6f60536381db242c7454132 339 Pfam PF12974 ABC transporter, phosphonate, periplasmic substrate-binding protein 39 288 1.8E-47 T 12-10-2018 VAPA_1c05900 93a281c7f6f60536381db242c7454132 339 TIGRFAM TIGR01098 3A0109s03R: phosphate/phosphite/phosphonate ABC transporter, periplasmic binding protein 11 256 3.0E-45 T 12-10-2018 IPR005770 Phosphate/phosphite/phosphonate ABC transporter, periplasmic binding protein GO:0043190|GO:0055085 VAPA_1c05900 93a281c7f6f60536381db242c7454132 339 Gene3D G3DSA:3.40.190.10 121 233 1.5E-58 T 12-10-2018 VAPA_1c05900 93a281c7f6f60536381db242c7454132 339 Gene3D G3DSA:3.40.190.10 37 262 1.5E-58 T 12-10-2018 VAPA_1c05900 93a281c7f6f60536381db242c7454132 339 SUPERFAMILY SSF53850 32 262 5.96E-22 T 12-10-2018 VAPA_2c13060 9155a256d1cf953852f00b185b267acf 173 Gene3D G3DSA:2.60.120.10 65 169 3.6E-16 T 12-10-2018 IPR014710 RmlC-like jelly roll fold VAPA_2c13060 9155a256d1cf953852f00b185b267acf 173 Pfam PF01381 Helix-turn-helix 5 48 1.0E-9 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 VAPA_2c13060 9155a256d1cf953852f00b185b267acf 173 Gene3D G3DSA:1.10.260.40 1 61 1.1E-12 T 12-10-2018 VAPA_2c13060 9155a256d1cf953852f00b185b267acf 173 Pfam PF07883 Cupin domain 99 167 1.4E-11 T 12-10-2018 IPR013096 Cupin 2, conserved barrel VAPA_2c13060 9155a256d1cf953852f00b185b267acf 173 SUPERFAMILY SSF51182 43 169 4.59E-21 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily VAPA_2c13060 9155a256d1cf953852f00b185b267acf 173 SUPERFAMILY SSF47413 3 54 2.59E-12 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 VAPA_2c13060 9155a256d1cf953852f00b185b267acf 173 SMART SM00530 1 50 1.8E-5 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 VAPA_1c49000 6e10d241c1b3f3d41a6157af29b7815e 274 Gene3D G3DSA:3.60.21.10 1 261 7.7E-32 T 12-10-2018 IPR029052 Metallo-dependent phosphatase-like VAPA_1c49000 6e10d241c1b3f3d41a6157af29b7815e 274 SUPERFAMILY SSF56300 4 234 4.19E-43 T 12-10-2018 VAPA_1c49000 6e10d241c1b3f3d41a6157af29b7815e 274 Pfam PF00149 Calcineurin-like phosphoesterase 5 191 2.4E-11 T 12-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 VAPA_1c26760 04d7db871486b842013e4bb9e2006c90 219 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 13 110 3.2E-26 T 12-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 VAPA_1c26760 04d7db871486b842013e4bb9e2006c90 219 SUPERFAMILY SSF161098 14 213 5.36E-43 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c26760 04d7db871486b842013e4bb9e2006c90 219 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 33 203 2.6E-21 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 VAPA_1c26760 04d7db871486b842013e4bb9e2006c90 219 Gene3D G3DSA:1.10.3720.10 1 216 4.6E-51 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c19210 95c8f3d9fabbe2d93a07646bf0c5d803 332 SMART SM01130 46 330 1.9E-84 T 12-10-2018 IPR002220 DapA-like GO:0016829 VAPA_1c19210 95c8f3d9fabbe2d93a07646bf0c5d803 332 PRINTS PR00146 Dihydrodipicolinate synthase signature 79 100 6.5E-13 T 12-10-2018 IPR002220 DapA-like GO:0016829 VAPA_1c19210 95c8f3d9fabbe2d93a07646bf0c5d803 332 PRINTS PR00146 Dihydrodipicolinate synthase signature 146 162 6.5E-13 T 12-10-2018 IPR002220 DapA-like GO:0016829 VAPA_1c19210 95c8f3d9fabbe2d93a07646bf0c5d803 332 PRINTS PR00146 Dihydrodipicolinate synthase signature 171 188 6.5E-13 T 12-10-2018 IPR002220 DapA-like GO:0016829 VAPA_1c19210 95c8f3d9fabbe2d93a07646bf0c5d803 332 PIRSF PIRSF001365 43 331 8.2E-71 T 12-10-2018 IPR002220 DapA-like GO:0016829 VAPA_1c19210 95c8f3d9fabbe2d93a07646bf0c5d803 332 SUPERFAMILY SSF51569 44 328 4.61E-75 T 12-10-2018 VAPA_1c19210 95c8f3d9fabbe2d93a07646bf0c5d803 332 Gene3D G3DSA:3.20.20.70 38 328 5.8E-76 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 VAPA_1c19210 95c8f3d9fabbe2d93a07646bf0c5d803 332 Pfam PF00701 Dihydrodipicolinate synthetase family 47 324 9.5E-48 T 12-10-2018 IPR002220 DapA-like GO:0016829 VAPA_1c19210 95c8f3d9fabbe2d93a07646bf0c5d803 332 Hamap MF_00418 4-hydroxy-tetrahydrodipicolinate synthase [dapA]. 46 328 42.099 T 12-10-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 VAPA_1c19210 95c8f3d9fabbe2d93a07646bf0c5d803 332 TIGRFAM TIGR00674 dapA: 4-hydroxy-tetrahydrodipicolinate synthase 54 322 5.0E-62 T 12-10-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 VAPA_1c19210 95c8f3d9fabbe2d93a07646bf0c5d803 332 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 176 206 - T 12-10-2018 IPR020625 Schiff base-forming aldolase, active site GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|Reactome: R-HSA-389661 VAPA_1c28940 35499a206da99baf9e2de427224a2173 240 Gene3D G3DSA:3.40.50.2300 4 131 7.8E-39 T 12-10-2018 VAPA_1c28940 35499a206da99baf9e2de427224a2173 240 SUPERFAMILY SSF46894 160 239 9.07E-22 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 VAPA_1c28940 35499a206da99baf9e2de427224a2173 240 SMART SM00448 6 117 1.6E-42 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_1c28940 35499a206da99baf9e2de427224a2173 240 Pfam PF00072 Response regulator receiver domain 8 118 1.4E-29 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_1c28940 35499a206da99baf9e2de427224a2173 240 Gene3D G3DSA:1.10.10.10 133 240 5.3E-29 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c28940 35499a206da99baf9e2de427224a2173 240 Pfam PF00486 Transcriptional regulatory protein, C terminal 164 238 3.5E-21 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 VAPA_1c28940 35499a206da99baf9e2de427224a2173 240 SMART SM00862 162 238 1.7E-21 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 VAPA_1c28940 35499a206da99baf9e2de427224a2173 240 SUPERFAMILY SSF52172 6 128 2.28E-41 T 12-10-2018 IPR011006 CheY-like superfamily VAPA_1c00330 7a4ce01c280ee6e84acb695d4c968954 408 SUPERFAMILY SSF53901 5 250 2.3E-49 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 VAPA_1c00330 7a4ce01c280ee6e84acb695d4c968954 408 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 259 365 3.2E-27 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal VAPA_1c00330 7a4ce01c280ee6e84acb695d4c968954 408 Gene3D G3DSA:3.40.47.10 262 408 3.6E-42 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 VAPA_1c00330 7a4ce01c280ee6e84acb695d4c968954 408 SMART SM00825 Beta-ketoacyl synthase 6 407 1.5E-12 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain VAPA_1c00330 7a4ce01c280ee6e84acb695d4c968954 408 Gene3D G3DSA:3.40.47.10 6 258 1.6E-56 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 VAPA_1c00330 7a4ce01c280ee6e84acb695d4c968954 408 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 5 246 1.1E-36 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal VAPA_1c00330 7a4ce01c280ee6e84acb695d4c968954 408 SUPERFAMILY SSF53901 215 405 5.76E-53 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 VAPA_1c18690 1e1cc025434a338f6beb9200bb2c1383 188 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 51 73 - T 12-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 VAPA_1c18690 1e1cc025434a338f6beb9200bb2c1383 188 Pfam PF01066 CDP-alcohol phosphatidyltransferase 5 73 5.0E-15 T 12-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 VAPA_1c18690 1e1cc025434a338f6beb9200bb2c1383 188 PIRSF PIRSF000847 1 188 6.0E-43 T 12-10-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 VAPA_1c18690 1e1cc025434a338f6beb9200bb2c1383 188 TIGRFAM TIGR00560 pgsA: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 5 182 2.2E-49 T 12-10-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 VAPA_1c18690 1e1cc025434a338f6beb9200bb2c1383 188 Gene3D G3DSA:1.20.120.1760 3 182 4.0E-14 T 12-10-2018 VAPA_1c54890 4e7a29a15f1af4ca98cf2f2edccc036e 454 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 129 138 - T 12-10-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 VAPA_1c54890 4e7a29a15f1af4ca98cf2f2edccc036e 454 Pfam PF07687 Peptidase dimerisation domain 237 335 2.2E-14 T 12-10-2018 IPR011650 Peptidase M20, dimerisation domain VAPA_1c54890 4e7a29a15f1af4ca98cf2f2edccc036e 454 Pfam PF01546 Peptidase family M20/M25/M40 130 426 3.2E-18 T 12-10-2018 IPR002933 Peptidase M20 GO:0016787 VAPA_1c54890 4e7a29a15f1af4ca98cf2f2edccc036e 454 Gene3D G3DSA:3.40.630.10 79 424 2.7E-58 T 12-10-2018 VAPA_1c54890 4e7a29a15f1af4ca98cf2f2edccc036e 454 SUPERFAMILY SSF55031 236 339 2.99E-14 T 12-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain VAPA_1c54890 4e7a29a15f1af4ca98cf2f2edccc036e 454 Gene3D G3DSA:3.30.70.360 233 353 2.7E-58 T 12-10-2018 VAPA_1c54890 4e7a29a15f1af4ca98cf2f2edccc036e 454 SUPERFAMILY SSF53187 70 436 4.57E-44 T 12-10-2018 VAPA_1c40430 9ba65d1ec7def4331b96d88b5ae50cb2 480 Gene3D G3DSA:3.40.605.10 12 473 2.2E-165 T 12-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 VAPA_1c40430 9ba65d1ec7def4331b96d88b5ae50cb2 480 SUPERFAMILY SSF53720 5 476 1.83E-161 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 VAPA_1c40430 9ba65d1ec7def4331b96d88b5ae50cb2 480 Gene3D G3DSA:3.40.309.10 256 445 2.2E-165 T 12-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 VAPA_1c40430 9ba65d1ec7def4331b96d88b5ae50cb2 480 Pfam PF00171 Aldehyde dehydrogenase family 16 475 1.6E-158 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 VAPA_1c50980 928e170980fc573acf4a5c02faea01f0 104 PRINTS PR00971 Ribosomal protein S10 family signature 6 19 2.9E-17 T 12-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VAPA_1c50980 928e170980fc573acf4a5c02faea01f0 104 PRINTS PR00971 Ribosomal protein S10 family signature 62 76 2.9E-17 T 12-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VAPA_1c50980 928e170980fc573acf4a5c02faea01f0 104 PRINTS PR00971 Ribosomal protein S10 family signature 41 56 2.9E-17 T 12-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VAPA_1c50980 928e170980fc573acf4a5c02faea01f0 104 SMART SM01403 8 102 7.2E-54 T 12-10-2018 IPR027486 Ribosomal protein S10 domain VAPA_1c50980 928e170980fc573acf4a5c02faea01f0 104 Pfam PF00338 Ribosomal protein S10p/S20e 8 102 1.2E-34 T 12-10-2018 IPR027486 Ribosomal protein S10 domain VAPA_1c50980 928e170980fc573acf4a5c02faea01f0 104 Hamap MF_00508 30S ribosomal protein S10 [rpsJ]. 4 103 27.264 T 12-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VAPA_1c50980 928e170980fc573acf4a5c02faea01f0 104 SUPERFAMILY SSF54999 6 103 7.85E-37 T 12-10-2018 IPR036838 Ribosomal protein S10 domain superfamily VAPA_1c50980 928e170980fc573acf4a5c02faea01f0 104 Gene3D G3DSA:3.30.70.600 1 103 1.4E-35 T 12-10-2018 IPR036838 Ribosomal protein S10 domain superfamily VAPA_1c50980 928e170980fc573acf4a5c02faea01f0 104 ProSitePatterns PS00361 Ribosomal protein S10 signature. 30 45 - T 12-10-2018 IPR018268 Ribosomal protein S10, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VAPA_1c50980 928e170980fc573acf4a5c02faea01f0 104 TIGRFAM TIGR01049 rpsJ_bact: ribosomal protein uS10 5 102 5.7E-45 T 12-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VAPA_2c01060 856ae8537eeec8dc3a6fb2b6d0a877a3 563 Pfam PF13193 AMP-binding enzyme C-terminal domain 466 543 1.1E-19 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain VAPA_2c01060 856ae8537eeec8dc3a6fb2b6d0a877a3 563 Pfam PF00501 AMP-binding enzyme 31 456 7.5E-107 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 VAPA_2c01060 856ae8537eeec8dc3a6fb2b6d0a877a3 563 SUPERFAMILY SSF56801 19 554 3.14E-152 T 12-10-2018 VAPA_2c01060 856ae8537eeec8dc3a6fb2b6d0a877a3 563 Gene3D G3DSA:3.40.50.12780 16 452 4.5E-117 T 12-10-2018 VAPA_2c01060 856ae8537eeec8dc3a6fb2b6d0a877a3 563 Gene3D G3DSA:3.30.300.310 453 558 1.5E-27 T 12-10-2018 VAPA_2c01060 856ae8537eeec8dc3a6fb2b6d0a877a3 563 ProSitePatterns PS00455 Putative AMP-binding domain signature. 208 219 - T 12-10-2018 IPR020845 AMP-binding, conserved site VAPA_2c06880 ef50aaba8744642586ece7ac281fd717 353 SMART SM01133 86 334 1.6E-70 T 12-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 VAPA_2c06880 ef50aaba8744642586ece7ac281fd717 353 Pfam PF01791 DeoC/LacD family aldolase 87 329 2.1E-23 T 12-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 VAPA_2c06880 ef50aaba8744642586ece7ac281fd717 353 Gene3D G3DSA:3.20.20.70 77 338 6.7E-85 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 VAPA_2c06880 ef50aaba8744642586ece7ac281fd717 353 TIGRFAM TIGR00126 deoC: deoxyribose-phosphate aldolase 89 313 4.0E-41 T 12-10-2018 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|Reactome: R-HSA-6798695|Reactome: R-HSA-71336 VAPA_2c06880 ef50aaba8744642586ece7ac281fd717 353 SUPERFAMILY SSF51569 81 336 2.62E-71 T 12-10-2018 VAPA_2c08140 1b8cdee411a1fa017794925d0c0e4c03 343 Gene3D G3DSA:3.40.190.10 48 318 1.2E-48 T 12-10-2018 VAPA_2c08140 1b8cdee411a1fa017794925d0c0e4c03 343 Pfam PF09084 NMT1/THI5 like 54 266 4.0E-20 T 12-10-2018 IPR015168 SsuA/THI5-like VAPA_2c08140 1b8cdee411a1fa017794925d0c0e4c03 343 Gene3D G3DSA:3.40.190.10 124 228 1.2E-48 T 12-10-2018 VAPA_2c08140 1b8cdee411a1fa017794925d0c0e4c03 343 SUPERFAMILY SSF53850 51 292 8.96E-31 T 12-10-2018 VAPA_2c03310 3dc5fc3a6c4b4255431f7d6bbd84de91 350 SUPERFAMILY SSF51735 142 307 9.03E-46 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_2c03310 3dc5fc3a6c4b4255431f7d6bbd84de91 350 SMART SM00829 13 337 3.0E-6 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 VAPA_2c03310 3dc5fc3a6c4b4255431f7d6bbd84de91 350 Pfam PF00107 Zinc-binding dehydrogenase 178 301 2.2E-29 T 12-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 VAPA_2c03310 3dc5fc3a6c4b4255431f7d6bbd84de91 350 SUPERFAMILY SSF50129 1 173 2.74E-54 T 12-10-2018 IPR011032 GroES-like superfamily VAPA_2c03310 3dc5fc3a6c4b4255431f7d6bbd84de91 350 Gene3D G3DSA:3.90.180.10 8 330 4.1E-133 T 12-10-2018 VAPA_2c03310 3dc5fc3a6c4b4255431f7d6bbd84de91 350 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 132 2.2E-32 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 VAPA_2c03310 3dc5fc3a6c4b4255431f7d6bbd84de91 350 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 63 77 - T 12-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 VAPA_2c03310 3dc5fc3a6c4b4255431f7d6bbd84de91 350 Gene3D G3DSA:3.40.50.720 151 288 4.1E-133 T 12-10-2018 VAPA_1c54880 7f044a40095308d696edd3f5f603a603 244 Gene3D G3DSA:3.40.1280.10 71 243 1.0E-52 T 12-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal VAPA_1c54880 7f044a40095308d696edd3f5f603a603 244 Pfam PF04452 RNA methyltransferase 23 241 1.2E-62 T 12-10-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 VAPA_1c54880 7f044a40095308d696edd3f5f603a603 244 PIRSF PIRSF015601 1 243 1.7E-53 T 12-10-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 VAPA_1c54880 7f044a40095308d696edd3f5f603a603 244 TIGRFAM TIGR00046 TIGR00046: RNA methyltransferase, RsmE family 22 241 2.2E-50 T 12-10-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 VAPA_1c54880 7f044a40095308d696edd3f5f603a603 244 SUPERFAMILY SSF88697 1 66 2.65E-13 T 12-10-2018 IPR015947 PUA-like superfamily VAPA_1c54880 7f044a40095308d696edd3f5f603a603 244 SUPERFAMILY SSF75217 71 241 6.98E-45 T 12-10-2018 IPR029028 Alpha/beta knot methyltransferases VAPA_1c54880 7f044a40095308d696edd3f5f603a603 244 Gene3D G3DSA:2.40.240.20 1 67 8.2E-20 T 12-10-2018 VAPA_1c06400 d547f6be32287fe102a5340212d6b603 465 SUPERFAMILY SSF53383 101 452 4.5E-64 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase VAPA_1c06400 d547f6be32287fe102a5340212d6b603 465 Pfam PF00155 Aminotransferase class I and II 123 446 2.5E-21 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 VAPA_1c06400 d547f6be32287fe102a5340212d6b603 465 SMART SM00345 23 82 2.8E-10 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_1c06400 d547f6be32287fe102a5340212d6b603 465 Gene3D G3DSA:3.90.1150.10 114 449 1.9E-53 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 VAPA_1c06400 d547f6be32287fe102a5340212d6b603 465 ProDom PD004527 LYASE II 3-DEHYDROQUINATE BIOSYNTHESIS DEHYDRATASE TYPE 3-DEHYDROQUINASE DHQASE AMINO AROMATIC 168 271 8.0E-4 T 12-10-2018 VAPA_1c06400 d547f6be32287fe102a5340212d6b603 465 SUPERFAMILY SSF46785 16 91 2.0E-14 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c06400 d547f6be32287fe102a5340212d6b603 465 Gene3D G3DSA:3.40.640.10 134 350 1.9E-53 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 VAPA_1c06400 d547f6be32287fe102a5340212d6b603 465 Gene3D G3DSA:1.10.10.10 10 83 7.8E-16 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c06400 d547f6be32287fe102a5340212d6b603 465 Pfam PF00392 Bacterial regulatory proteins, gntR family 23 82 3.6E-10 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_1c12430 73118227bd3a22e484b45201947644fb 447 Pfam PF07690 Major Facilitator Superfamily 71 393 3.8E-26 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 VAPA_1c12430 73118227bd3a22e484b45201947644fb 447 Gene3D G3DSA:1.20.1250.20 23 434 5.4E-53 T 12-10-2018 VAPA_1c12430 73118227bd3a22e484b45201947644fb 447 SUPERFAMILY SSF103473 2 428 1.29E-56 T 12-10-2018 IPR036259 MFS transporter superfamily VAPA_2c09920 d954c5697e9a2d49108084396434baab 208 Pfam PF00440 Bacterial regulatory proteins, tetR family 25 71 7.0E-16 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 VAPA_2c09920 d954c5697e9a2d49108084396434baab 208 Gene3D G3DSA:1.10.357.10 20 208 2.0E-43 T 12-10-2018 VAPA_2c09920 d954c5697e9a2d49108084396434baab 208 ProSitePatterns PS01081 TetR-type HTH domain signature. 37 68 - T 12-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site VAPA_2c09920 d954c5697e9a2d49108084396434baab 208 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 25 38 1.7E-9 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 VAPA_2c09920 d954c5697e9a2d49108084396434baab 208 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 46 69 1.7E-9 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 VAPA_2c09920 d954c5697e9a2d49108084396434baab 208 SUPERFAMILY SSF46689 13 89 4.84E-19 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 VAPA_1c28830 cf5f27000a52e49077fcffcdee704e31 450 Pfam PF12471 GTP cyclohydrolase N terminal 43 229 3.3E-78 T 12-10-2018 IPR022163 GTP cyclohydrolase N-terminal VAPA_1c28830 cf5f27000a52e49077fcffcdee704e31 450 Pfam PF00925 GTP cyclohydrolase II 261 405 3.4E-15 T 12-10-2018 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 VAPA_1c28830 cf5f27000a52e49077fcffcdee704e31 450 SUPERFAMILY SSF142695 235 408 3.66E-30 T 12-10-2018 IPR036144 RibA-like superfamily KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 VAPA_1c28830 cf5f27000a52e49077fcffcdee704e31 450 Gene3D G3DSA:3.40.50.10990 250 408 1.3E-31 T 12-10-2018 IPR036144 RibA-like superfamily KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 VAPA_1c34780 528689efd6d66ad6e1ec41cc5e292989 359 Gene3D G3DSA:3.40.47.10 219 358 6.5E-27 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 VAPA_1c34780 528689efd6d66ad6e1ec41cc5e292989 359 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 113 204 3.1E-19 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal VAPA_1c34780 528689efd6d66ad6e1ec41cc5e292989 359 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 225 315 6.7E-20 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal VAPA_1c34780 528689efd6d66ad6e1ec41cc5e292989 359 Gene3D G3DSA:3.40.47.10 52 218 3.7E-23 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 VAPA_1c34780 528689efd6d66ad6e1ec41cc5e292989 359 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 125 141 - T 12-10-2018 IPR018201 Beta-ketoacyl synthase, active site VAPA_1c34780 528689efd6d66ad6e1ec41cc5e292989 359 SUPERFAMILY SSF53901 108 355 3.43E-38 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 VAPA_1c34780 528689efd6d66ad6e1ec41cc5e292989 359 SMART SM00825 Beta-ketoacyl synthase 12 358 1.0E-7 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain VAPA_1c47120 3cecab73f11b1167adea5921967ff00b 271 SMART SM00342 178 261 1.1E-24 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 VAPA_1c47120 3cecab73f11b1167adea5921967ff00b 271 SMART SM00448 11 124 1.3E-25 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_1c47120 3cecab73f11b1167adea5921967ff00b 271 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 245 261 1.1E-6 T 12-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 VAPA_1c47120 3cecab73f11b1167adea5921967ff00b 271 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 230 245 1.1E-6 T 12-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 VAPA_1c47120 3cecab73f11b1167adea5921967ff00b 271 Pfam PF12833 Helix-turn-helix domain 184 262 7.2E-22 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 VAPA_1c47120 3cecab73f11b1167adea5921967ff00b 271 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 215 257 - T 12-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 VAPA_1c47120 3cecab73f11b1167adea5921967ff00b 271 SUPERFAMILY SSF46689 165 212 7.62E-5 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 VAPA_1c47120 3cecab73f11b1167adea5921967ff00b 271 Gene3D G3DSA:1.10.10.60 158 269 1.1E-26 T 12-10-2018 VAPA_1c47120 3cecab73f11b1167adea5921967ff00b 271 SUPERFAMILY SSF46689 215 262 1.34E-12 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 VAPA_1c47120 3cecab73f11b1167adea5921967ff00b 271 Gene3D G3DSA:3.40.50.2300 5 136 4.5E-25 T 12-10-2018 VAPA_1c47120 3cecab73f11b1167adea5921967ff00b 271 Pfam PF00072 Response regulator receiver domain 13 124 1.3E-15 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_1c47120 3cecab73f11b1167adea5921967ff00b 271 SUPERFAMILY SSF52172 6 133 1.15E-30 T 12-10-2018 IPR011006 CheY-like superfamily VAPA_1c54470 4d798466e7e476fd0b971d427cd41dda 286 PIRSF PIRSF006232 9 284 2.3E-54 T 12-10-2018 IPR012093 Pirin Reactome: R-HSA-8935690 VAPA_1c54470 4d798466e7e476fd0b971d427cd41dda 286 Gene3D G3DSA:2.60.120.10 11 249 5.1E-49 T 12-10-2018 IPR014710 RmlC-like jelly roll fold VAPA_1c54470 4d798466e7e476fd0b971d427cd41dda 286 SUPERFAMILY SSF51182 14 275 9.79E-51 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily VAPA_1c54470 4d798466e7e476fd0b971d427cd41dda 286 Pfam PF02678 Pirin 38 126 1.1E-26 T 12-10-2018 IPR003829 Pirin, N-terminal domain Reactome: R-HSA-8935690 VAPA_1c24770 e3a84cada9d00245146f71a6817f1ee2 259 SMART SM00849 11 169 4.4E-37 T 12-10-2018 IPR001279 Metallo-beta-lactamase VAPA_1c24770 e3a84cada9d00245146f71a6817f1ee2 259 Pfam PF16123 Hydroxyacylglutathione hydrolase C-terminus 170 258 3.8E-27 T 12-10-2018 IPR032282 Hydroxyacylglutathione hydrolase, C-terminal domain KEGG: 00620+3.1.2.6|MetaCyc: PWY-5386 VAPA_1c24770 e3a84cada9d00245146f71a6817f1ee2 259 Gene3D G3DSA:3.60.15.10 1 258 2.1E-86 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like VAPA_1c24770 e3a84cada9d00245146f71a6817f1ee2 259 PIRSF PIRSF005457 1 258 4.3E-104 T 12-10-2018 IPR017782 Hydroxyacylglutathione hydrolase GO:0004416|GO:0019243 KEGG: 00620+3.1.2.6|MetaCyc: PWY-5386 VAPA_1c24770 e3a84cada9d00245146f71a6817f1ee2 259 SUPERFAMILY SSF56281 1 258 2.23E-71 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like VAPA_1c24770 e3a84cada9d00245146f71a6817f1ee2 259 Pfam PF00753 Metallo-beta-lactamase superfamily 13 169 3.4E-16 T 12-10-2018 IPR001279 Metallo-beta-lactamase VAPA_1c24770 e3a84cada9d00245146f71a6817f1ee2 259 Hamap MF_01374 Hydroxyacylglutathione hydrolase [gloB]. 1 258 44.122 T 12-10-2018 IPR017782 Hydroxyacylglutathione hydrolase GO:0004416|GO:0019243 KEGG: 00620+3.1.2.6|MetaCyc: PWY-5386 VAPA_1c24770 e3a84cada9d00245146f71a6817f1ee2 259 TIGRFAM TIGR03413 GSH_gloB: hydroxyacylglutathione hydrolase 4 258 2.6E-101 T 12-10-2018 IPR017782 Hydroxyacylglutathione hydrolase GO:0004416|GO:0019243 KEGG: 00620+3.1.2.6|MetaCyc: PWY-5386 VAPA_1c42580 63b0d57d5862cdae4003e6811efa64b4 247 PIRSF PIRSF000709 132 221 5.1 T 12-10-2018 VAPA_1c42580 63b0d57d5862cdae4003e6811efa64b4 247 PIRSF PIRSF000709 2 111 3.0E-8 T 12-10-2018 VAPA_1c42580 63b0d57d5862cdae4003e6811efa64b4 247 Hamap MF_01039 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [gpmA]. 1 228 45.538 T 12-10-2018 IPR005952 Phosphoglycerate mutase 1 GO:0004619|GO:0006096|GO:0016868 KEGG: 00010+5.4.2.11|KEGG: 00260+5.4.2.11|KEGG: 00680+5.4.2.11|MetaCyc: PWY-1622|MetaCyc: PWY-5484 VAPA_1c42580 63b0d57d5862cdae4003e6811efa64b4 247 Gene3D G3DSA:3.40.50.1240 1 247 1.4E-90 T 12-10-2018 IPR029033 Histidine phosphatase superfamily VAPA_1c42580 63b0d57d5862cdae4003e6811efa64b4 247 SUPERFAMILY SSF53254 1 245 4.06E-79 T 12-10-2018 IPR029033 Histidine phosphatase superfamily VAPA_1c42580 63b0d57d5862cdae4003e6811efa64b4 247 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 4 125 2.5E-31 T 12-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 VAPA_1c42580 63b0d57d5862cdae4003e6811efa64b4 247 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 143 218 1.4E-4 T 12-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 VAPA_1c42580 63b0d57d5862cdae4003e6811efa64b4 247 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 6 15 - T 12-10-2018 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824 VAPA_1c42580 63b0d57d5862cdae4003e6811efa64b4 247 TIGRFAM TIGR01258 pgm_1: phosphoglycerate mutase 1 family 2 246 3.4E-118 T 12-10-2018 IPR005952 Phosphoglycerate mutase 1 GO:0004619|GO:0006096|GO:0016868 KEGG: 00010+5.4.2.11|KEGG: 00260+5.4.2.11|KEGG: 00680+5.4.2.11|MetaCyc: PWY-1622|MetaCyc: PWY-5484 VAPA_1c42580 63b0d57d5862cdae4003e6811efa64b4 247 SMART SM00855 3 189 5.4E-29 T 12-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 VAPA_1c24930 6869a866d5f7abea79ce3f626c6664d0 278 Pfam PF10118 Predicted metal-dependent hydrolase 6 252 1.1E-72 T 12-10-2018 IPR016516 Uncharacterised conserved protein UCP07580 VAPA_1c24930 6869a866d5f7abea79ce3f626c6664d0 278 PIRSF PIRSF007580 2 269 2.0E-60 T 12-10-2018 IPR016516 Uncharacterised conserved protein UCP07580 VAPA_1c24930 6869a866d5f7abea79ce3f626c6664d0 278 SUPERFAMILY SSF47240 33 186 8.92E-6 T 12-10-2018 IPR009078 Ferritin-like superfamily VAPA_1c15510 d17486822d01232836cd1f23629cea48 142 SUPERFAMILY SSF54909 1 114 1.37E-33 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel VAPA_1c15510 d17486822d01232836cd1f23629cea48 142 Pfam PF03795 YCII-related domain 1 111 1.4E-25 T 12-10-2018 IPR005545 YCII-related VAPA_1c15510 d17486822d01232836cd1f23629cea48 142 Gene3D G3DSA:3.30.70.1060 1 114 2.0E-34 T 12-10-2018 VAPA_2c09140 3fb3320ae7d8ca575701be8ec5e05451 295 SUPERFAMILY SSF46785 10 114 2.39E-21 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_2c09140 3fb3320ae7d8ca575701be8ec5e05451 295 SUPERFAMILY SSF53850 93 294 1.69E-40 T 12-10-2018 VAPA_2c09140 3fb3320ae7d8ca575701be8ec5e05451 295 Gene3D G3DSA:3.40.190.10 165 262 1.0E-56 T 12-10-2018 VAPA_2c09140 3fb3320ae7d8ca575701be8ec5e05451 295 Gene3D G3DSA:3.40.190.10 93 288 1.0E-56 T 12-10-2018 VAPA_2c09140 3fb3320ae7d8ca575701be8ec5e05451 295 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 10 65 2.3E-19 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_2c09140 3fb3320ae7d8ca575701be8ec5e05451 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 33 43 2.2E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_2c09140 3fb3320ae7d8ca575701be8ec5e05451 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 22 33 2.2E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_2c09140 3fb3320ae7d8ca575701be8ec5e05451 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 43 54 2.2E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_2c09140 3fb3320ae7d8ca575701be8ec5e05451 295 Pfam PF03466 LysR substrate binding domain 92 291 6.6E-39 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_2c09140 3fb3320ae7d8ca575701be8ec5e05451 295 Gene3D G3DSA:1.10.10.10 7 90 1.3E-25 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c22160 9b938e8dcafee6f21a2f1deb60845833 226 Pfam PF13545 Crp-like helix-turn-helix domain 155 225 1.2E-12 T 12-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 VAPA_1c22160 9b938e8dcafee6f21a2f1deb60845833 226 SUPERFAMILY SSF46785 153 225 2.73E-12 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c22160 9b938e8dcafee6f21a2f1deb60845833 226 Gene3D G3DSA:1.10.10.10 136 226 2.7E-13 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c22160 9b938e8dcafee6f21a2f1deb60845833 226 SMART SM00100 16 137 3.2E-5 T 12-10-2018 IPR000595 Cyclic nucleotide-binding domain VAPA_1c22160 9b938e8dcafee6f21a2f1deb60845833 226 Pfam PF00027 Cyclic nucleotide-binding domain 35 121 2.4E-10 T 12-10-2018 IPR000595 Cyclic nucleotide-binding domain VAPA_1c22160 9b938e8dcafee6f21a2f1deb60845833 226 SUPERFAMILY SSF51206 10 144 1.57E-20 T 12-10-2018 IPR018490 Cyclic nucleotide-binding-like VAPA_1c22160 9b938e8dcafee6f21a2f1deb60845833 226 SMART SM00419 170 218 1.9E-5 T 12-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 VAPA_1c22160 9b938e8dcafee6f21a2f1deb60845833 226 Gene3D G3DSA:2.60.120.10 5 135 1.5E-12 T 12-10-2018 IPR014710 RmlC-like jelly roll fold VAPA_1c48540 53e77c6d5911afdad1374c63faca5ec7 318 PIRSF PIRSF036979 17 315 2.2E-99 T 12-10-2018 IPR006035 Ureohydrolase GO:0046872 VAPA_1c48540 53e77c6d5911afdad1374c63faca5ec7 318 PRINTS PR00116 Arginase signature 123 138 5.7E-13 T 12-10-2018 IPR006035 Ureohydrolase GO:0046872 VAPA_1c48540 53e77c6d5911afdad1374c63faca5ec7 318 PRINTS PR00116 Arginase signature 237 266 5.7E-13 T 12-10-2018 IPR006035 Ureohydrolase GO:0046872 VAPA_1c48540 53e77c6d5911afdad1374c63faca5ec7 318 Pfam PF00491 Arginase family 37 309 2.4E-89 T 12-10-2018 IPR006035 Ureohydrolase GO:0046872 VAPA_1c48540 53e77c6d5911afdad1374c63faca5ec7 318 Gene3D G3DSA:3.40.800.10 4 318 1.1E-118 T 12-10-2018 VAPA_1c48540 53e77c6d5911afdad1374c63faca5ec7 318 SUPERFAMILY SSF52768 15 311 1.57E-101 T 12-10-2018 IPR023696 Ureohydrolase domain superfamily VAPA_1c48540 53e77c6d5911afdad1374c63faca5ec7 318 TIGRFAM TIGR01230 agmatinase: agmatinase 37 310 4.2E-61 T 12-10-2018 IPR005925 Agmatinase-related KEGG: 00330+3.5.3.11|MetaCyc: PWY-40|MetaCyc: PWY-6305|Reactome: R-HSA-351143 VAPA_1c39500 07e6026d9146cf260a8f0fdafc6ce40c 161 Pfam PF00196 Bacterial regulatory proteins, luxR family 100 154 3.5E-16 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_1c39500 07e6026d9146cf260a8f0fdafc6ce40c 161 SMART SM00421 97 154 1.4E-20 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_1c39500 07e6026d9146cf260a8f0fdafc6ce40c 161 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 100 114 9.7E-11 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_1c39500 07e6026d9146cf260a8f0fdafc6ce40c 161 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 114 130 9.7E-11 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_1c39500 07e6026d9146cf260a8f0fdafc6ce40c 161 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 130 142 9.7E-11 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_1c39500 07e6026d9146cf260a8f0fdafc6ce40c 161 SUPERFAMILY SSF46894 87 159 1.43E-19 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 VAPA_1c39500 07e6026d9146cf260a8f0fdafc6ce40c 161 Gene3D G3DSA:1.10.10.10 4 161 3.3E-23 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c10070 9e2f92d7330bf6a44bb0d5f703709086 390 SUPERFAMILY SSF47240 55 361 3.6E-97 T 12-10-2018 IPR009078 Ferritin-like superfamily VAPA_1c10070 9e2f92d7330bf6a44bb0d5f703709086 390 PIRSF PIRSF000355 42 390 3.6E-133 T 12-10-2018 IPR000358 Ribonucleotide reductase small subunit family GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 VAPA_1c10070 9e2f92d7330bf6a44bb0d5f703709086 390 Pfam PF00268 Ribonucleotide reductase, small chain 70 357 8.5E-86 T 12-10-2018 IPR000358 Ribonucleotide reductase small subunit family GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 VAPA_1c10070 9e2f92d7330bf6a44bb0d5f703709086 390 Gene3D G3DSA:1.10.620.20 46 383 5.9E-114 T 12-10-2018 IPR012348 Ribonucleotide reductase-like GO:0016491|GO:0055114 Reactome: R-HSA-499943 VAPA_1c26820 9f7f189e680684f4931c2e462d120c0d 791 Gene3D G3DSA:1.10.10.650 1 108 8.9E-40 T 12-10-2018 IPR023319 Tex-like protein, HTH domain superfamily VAPA_1c26820 9f7f189e680684f4931c2e462d120c0d 791 Pfam PF16921 Tex protein YqgF-like domain 336 471 3.4E-49 T 12-10-2018 IPR032639 Tex protein, YqgF-like domain VAPA_1c26820 9f7f189e680684f4931c2e462d120c0d 791 SMART SM00316 669 740 8.2E-24 T 12-10-2018 IPR022967 RNA-binding domain, S1 VAPA_1c26820 9f7f189e680684f4931c2e462d120c0d 791 Gene3D G3DSA:1.10.150.310 519 650 7.6E-46 T 12-10-2018 VAPA_1c26820 9f7f189e680684f4931c2e462d120c0d 791 SUPERFAMILY SSF47781 490 578 3.0E-26 T 12-10-2018 IPR010994 RuvA domain 2-like VAPA_1c26820 9f7f189e680684f4931c2e462d120c0d 791 Gene3D G3DSA:3.30.420.140 335 471 1.5E-146 T 12-10-2018 IPR037027 YqgF/RNase H-like domain superfamily GO:0006139 VAPA_1c26820 9f7f189e680684f4931c2e462d120c0d 791 Pfam PF12836 Helix-hairpin-helix motif 511 575 3.5E-25 T 12-10-2018 VAPA_1c26820 9f7f189e680684f4931c2e462d120c0d 791 Gene3D G3DSA:2.40.50.140 651 744 5.0E-27 T 12-10-2018 VAPA_1c26820 9f7f189e680684f4931c2e462d120c0d 791 SUPERFAMILY SSF53098 332 489 3.64E-48 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily VAPA_1c26820 9f7f189e680684f4931c2e462d120c0d 791 Pfam PF09371 Tex-like protein N-terminal domain 8 200 3.9E-65 T 12-10-2018 IPR018974 Tex-like protein, N-terminal VAPA_1c26820 9f7f189e680684f4931c2e462d120c0d 791 SUPERFAMILY SSF50249 658 741 2.39E-23 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold VAPA_1c26820 9f7f189e680684f4931c2e462d120c0d 791 Pfam PF00575 S1 RNA binding domain 670 740 2.0E-19 T 12-10-2018 IPR003029 S1 domain GO:0003676 VAPA_1c26820 9f7f189e680684f4931c2e462d120c0d 791 SUPERFAMILY SSF158832 1 331 1.44E-107 T 12-10-2018 VAPA_1c26820 9f7f189e680684f4931c2e462d120c0d 791 SUPERFAMILY SSF47781 581 652 1.87E-18 T 12-10-2018 IPR010994 RuvA domain 2-like VAPA_1c26820 9f7f189e680684f4931c2e462d120c0d 791 Gene3D G3DSA:1.10.3500.10 111 518 1.5E-146 T 12-10-2018 IPR023323 Tex-like domain superfamily VAPA_1c26820 9f7f189e680684f4931c2e462d120c0d 791 SMART SM00732 336 444 1.2E-32 T 12-10-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 VAPA_1c09550 822242f6bbb10833638e94f2642acf64 346 Hamap MF_01808 Tyrosine recombinase XerC [xerC]. 11 318 53.513 T 12-10-2018 IPR023009 Tyrosine recombinase XerC/XerD VAPA_1c09550 822242f6bbb10833638e94f2642acf64 346 SUPERFAMILY SSF56349 12 311 1.8E-46 T 12-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 VAPA_1c09550 822242f6bbb10833638e94f2642acf64 346 Pfam PF00589 Phage integrase family 121 304 6.6E-39 T 12-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 VAPA_1c09550 822242f6bbb10833638e94f2642acf64 346 Gene3D G3DSA:1.10.150.130 10 104 1.5E-15 T 12-10-2018 IPR010998 Integrase/recombinase, N-terminal VAPA_1c09550 822242f6bbb10833638e94f2642acf64 346 Gene3D G3DSA:1.10.443.10 116 312 1.5E-49 T 12-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 VAPA_1c09550 822242f6bbb10833638e94f2642acf64 346 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 13 95 6.0E-13 T 12-10-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 VAPA_1c03370 5537fa683fbf0918d0e0e73b14420fc0 321 PIRSF PIRSF017082 1 321 6.6E-77 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c03370 5537fa683fbf0918d0e0e73b14420fc0 321 Gene3D G3DSA:3.40.190.150 25 311 8.8E-107 T 12-10-2018 VAPA_1c03370 5537fa683fbf0918d0e0e73b14420fc0 321 SUPERFAMILY SSF53850 102 283 1.84E-16 T 12-10-2018 VAPA_1c03370 5537fa683fbf0918d0e0e73b14420fc0 321 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 44 316 6.6E-81 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c03370 5537fa683fbf0918d0e0e73b14420fc0 321 Gene3D G3DSA:3.40.190.10 122 246 8.8E-107 T 12-10-2018 VAPA_1c51870 178a4469dac3a5f65bb00fe6b63009bd 193 ProSitePatterns PS00088 Manganese and iron superoxide dismutases signature. 157 164 - T 12-10-2018 IPR019833 Manganese/iron superoxide dismutase, binding site GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 VAPA_1c51870 178a4469dac3a5f65bb00fe6b63009bd 193 SUPERFAMILY SSF46609 1 84 1.96E-33 T 12-10-2018 IPR036324 Manganese/iron superoxide dismutase, N-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 VAPA_1c51870 178a4469dac3a5f65bb00fe6b63009bd 193 Pfam PF02777 Iron/manganese superoxide dismutases, C-terminal domain 89 190 2.7E-34 T 12-10-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 VAPA_1c51870 178a4469dac3a5f65bb00fe6b63009bd 193 PIRSF PIRSF000349 1 193 8.1E-79 T 12-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 VAPA_1c51870 178a4469dac3a5f65bb00fe6b63009bd 193 PRINTS PR01703 Manganese superoxide dismutase signature 65 78 3.1E-22 T 12-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 VAPA_1c51870 178a4469dac3a5f65bb00fe6b63009bd 193 PRINTS PR01703 Manganese superoxide dismutase signature 6 17 3.1E-22 T 12-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 VAPA_1c51870 178a4469dac3a5f65bb00fe6b63009bd 193 PRINTS PR01703 Manganese superoxide dismutase signature 27 40 3.1E-22 T 12-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 VAPA_1c51870 178a4469dac3a5f65bb00fe6b63009bd 193 PRINTS PR01703 Manganese superoxide dismutase signature 118 126 3.1E-22 T 12-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 VAPA_1c51870 178a4469dac3a5f65bb00fe6b63009bd 193 PRINTS PR01703 Manganese superoxide dismutase signature 155 167 3.1E-22 T 12-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 VAPA_1c51870 178a4469dac3a5f65bb00fe6b63009bd 193 Pfam PF00081 Iron/manganese superoxide dismutases, alpha-hairpin domain 2 82 1.2E-31 T 12-10-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 VAPA_1c51870 178a4469dac3a5f65bb00fe6b63009bd 193 SUPERFAMILY SSF54719 85 192 1.44E-40 T 12-10-2018 IPR036314 Manganese/iron superoxide dismutase, C-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 VAPA_1c51870 178a4469dac3a5f65bb00fe6b63009bd 193 Gene3D G3DSA:2.40.500.20 83 193 9.1E-38 T 12-10-2018 IPR036314 Manganese/iron superoxide dismutase, C-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 VAPA_1c51870 178a4469dac3a5f65bb00fe6b63009bd 193 Gene3D G3DSA:1.10.287.990 20 81 5.1E-25 T 12-10-2018 IPR036324 Manganese/iron superoxide dismutase, N-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 VAPA_1c23900 90a13b5a778d50f680ce640f263da32b 195 Pfam PF01381 Helix-turn-helix 24 75 7.1E-12 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 VAPA_1c23900 90a13b5a778d50f680ce640f263da32b 195 Gene3D G3DSA:2.60.120.10 87 195 1.4E-9 T 12-10-2018 IPR014710 RmlC-like jelly roll fold VAPA_1c23900 90a13b5a778d50f680ce640f263da32b 195 SMART SM00530 21 76 5.3E-13 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 VAPA_1c23900 90a13b5a778d50f680ce640f263da32b 195 Gene3D G3DSA:1.10.260.40 11 86 6.3E-17 T 12-10-2018 VAPA_1c23900 90a13b5a778d50f680ce640f263da32b 195 SUPERFAMILY SSF51182 62 195 1.54E-18 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily VAPA_1c23900 90a13b5a778d50f680ce640f263da32b 195 SUPERFAMILY SSF47413 15 81 1.9E-15 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 VAPA_2c03300 1a3869df4112f27ea02d17a5c9e80730 248 SUPERFAMILY SSF52172 5 124 3.84E-33 T 12-10-2018 IPR011006 CheY-like superfamily VAPA_2c03300 1a3869df4112f27ea02d17a5c9e80730 248 SUPERFAMILY SSF46894 143 243 1.79E-26 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 VAPA_2c03300 1a3869df4112f27ea02d17a5c9e80730 248 SMART SM00862 165 241 8.1E-25 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 VAPA_2c03300 1a3869df4112f27ea02d17a5c9e80730 248 SMART SM00448 5 115 8.2E-33 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_2c03300 1a3869df4112f27ea02d17a5c9e80730 248 Gene3D G3DSA:1.10.10.10 133 246 6.3E-35 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_2c03300 1a3869df4112f27ea02d17a5c9e80730 248 Gene3D G3DSA:3.40.50.2300 1 122 3.1E-29 T 12-10-2018 VAPA_2c03300 1a3869df4112f27ea02d17a5c9e80730 248 Pfam PF00072 Response regulator receiver domain 7 116 4.8E-22 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_2c03300 1a3869df4112f27ea02d17a5c9e80730 248 Pfam PF00486 Transcriptional regulatory protein, C terminal 165 241 2.2E-23 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 VAPA_2c09680 a00adf295f18dd8eaa74e78aa5d64160 319 Gene3D G3DSA:3.40.718.10 2 317 7.9E-86 T 12-10-2018 VAPA_2c09680 a00adf295f18dd8eaa74e78aa5d64160 319 SUPERFAMILY SSF53659 7 313 1.67E-75 T 12-10-2018 VAPA_2c09680 a00adf295f18dd8eaa74e78aa5d64160 319 Pfam PF04166 Pyridoxal phosphate biosynthetic protein PdxA 37 312 1.4E-64 T 12-10-2018 IPR005255 PdxA family GO:0051287|GO:0055114 KEGG: 00750+1.1.1.262 VAPA_1c42250 358300916bbcb7e783e9e1da586fa695 609 Pfam PF10531 SLBB domain 446 495 5.3E-9 T 12-10-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VAPA_1c42250 358300916bbcb7e783e9e1da586fa695 609 Gene3D G3DSA:3.40.30.10 124 213 1.5E-12 T 12-10-2018 VAPA_1c42250 358300916bbcb7e783e9e1da586fa695 609 Gene3D G3DSA:1.10.10.1590 45 115 1.3E-7 T 12-10-2018 VAPA_1c42250 358300916bbcb7e783e9e1da586fa695 609 Pfam PF01257 Thioredoxin-like [2Fe-2S] ferredoxin 64 195 2.0E-24 T 12-10-2018 VAPA_1c42250 358300916bbcb7e783e9e1da586fa695 609 SMART SM00928 532 577 2.8E-21 T 12-10-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VAPA_1c42250 358300916bbcb7e783e9e1da586fa695 609 ProSitePatterns PS00645 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 2. 545 556 - T 12-10-2018 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VAPA_1c42250 358300916bbcb7e783e9e1da586fa695 609 Gene3D G3DSA:3.40.50.11540 265 434 8.2E-63 T 12-10-2018 IPR037225 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VAPA_1c42250 358300916bbcb7e783e9e1da586fa695 609 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 260 421 1.6E-39 T 12-10-2018 IPR011538 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VAPA_1c42250 358300916bbcb7e783e9e1da586fa695 609 Pfam PF10589 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region 533 608 6.3E-21 T 12-10-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VAPA_1c42250 358300916bbcb7e783e9e1da586fa695 609 SUPERFAMILY SSF52833 56 200 2.12E-33 T 12-10-2018 IPR036249 Thioredoxin-like superfamily VAPA_1c42250 358300916bbcb7e783e9e1da586fa695 609 SUPERFAMILY SSF142984 444 526 5.62E-21 T 12-10-2018 VAPA_1c42250 358300916bbcb7e783e9e1da586fa695 609 Gene3D G3DSA:1.20.1440.230 531 609 6.1E-22 T 12-10-2018 IPR037207 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VAPA_1c42250 358300916bbcb7e783e9e1da586fa695 609 Gene3D G3DSA:3.10.20.600 435 528 4.2E-25 T 12-10-2018 VAPA_1c42250 358300916bbcb7e783e9e1da586fa695 609 SUPERFAMILY SSF142019 230 442 1.44E-64 T 12-10-2018 IPR037225 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VAPA_1c42250 358300916bbcb7e783e9e1da586fa695 609 SUPERFAMILY SSF140490 532 608 9.81E-24 T 12-10-2018 IPR037207 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VAPA_1c42250 358300916bbcb7e783e9e1da586fa695 609 ProSitePatterns PS00644 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 1. 370 385 - T 12-10-2018 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VAPA_1c46690 33f2cbab59535255625bf8de0002bdea 174 Pfam PF07331 Tripartite tricarboxylate transporter TctB family 24 161 1.5E-19 T 12-10-2018 IPR009936 Protein of unknown function DUF1468 VAPA_2c09450 509e1b2c1a14d5e688c838f0ca56a700 125 Pfam PF08000 Bacterial PH domain 3 122 1.3E-49 T 12-10-2018 IPR012544 Bacterial Pleckstrin homology domain VAPA_2c09450 509e1b2c1a14d5e688c838f0ca56a700 125 SUPERFAMILY SSF50729 6 124 2.89E-44 T 12-10-2018 VAPA_2c09450 509e1b2c1a14d5e688c838f0ca56a700 125 Gene3D G3DSA:2.30.29.50 1 125 8.0E-53 T 12-10-2018 IPR037063 Bacterial Pleckstrin homology domain superfamily VAPA_1c50320 13ed7793c3a34e50de29ad875264dc4f 149 ProSitePatterns PS00194 Thioredoxin family active site. 64 82 - T 12-10-2018 IPR017937 Thioredoxin, conserved site GO:0045454 VAPA_1c50320 13ed7793c3a34e50de29ad875264dc4f 149 Pfam PF00085 Thioredoxin 48 146 2.7E-29 T 12-10-2018 IPR013766 Thioredoxin domain GO:0045454 VAPA_1c50320 13ed7793c3a34e50de29ad875264dc4f 149 SUPERFAMILY SSF52833 31 146 1.16E-36 T 12-10-2018 IPR036249 Thioredoxin-like superfamily VAPA_1c50320 13ed7793c3a34e50de29ad875264dc4f 149 TIGRFAM TIGR01068 thioredoxin: thioredoxin 49 145 1.1E-30 T 12-10-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 VAPA_1c50320 13ed7793c3a34e50de29ad875264dc4f 149 PRINTS PR00421 Thioredoxin family signature 63 71 6.0E-9 T 12-10-2018 VAPA_1c50320 13ed7793c3a34e50de29ad875264dc4f 149 PRINTS PR00421 Thioredoxin family signature 111 122 6.0E-9 T 12-10-2018 VAPA_1c50320 13ed7793c3a34e50de29ad875264dc4f 149 PRINTS PR00421 Thioredoxin family signature 71 80 6.0E-9 T 12-10-2018 VAPA_1c50320 13ed7793c3a34e50de29ad875264dc4f 149 PIRSF PIRSF000077 42 147 4.1E-30 T 12-10-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 VAPA_1c50320 13ed7793c3a34e50de29ad875264dc4f 149 Gene3D G3DSA:3.40.30.10 41 148 6.6E-31 T 12-10-2018 VAPA_1c50320 13ed7793c3a34e50de29ad875264dc4f 149 Gene3D G3DSA:2.20.28.140 5 40 2.8E-10 T 12-10-2018 VAPA_1c21890 e57df96ef497dac834fbd9486b892ade 380 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 230 375 5.8E-46 T 12-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 VAPA_1c21890 e57df96ef497dac834fbd9486b892ade 380 PIRSF PIRSF016578 4 376 3.5E-21 T 12-10-2018 VAPA_1c21890 e57df96ef497dac834fbd9486b892ade 380 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 113 1.5E-25 T 12-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 VAPA_1c21890 e57df96ef497dac834fbd9486b892ade 380 Gene3D G3DSA:1.10.540.10 1 117 1.2E-31 T 12-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 VAPA_1c21890 e57df96ef497dac834fbd9486b892ade 380 SUPERFAMILY SSF47203 226 378 9.5E-55 T 12-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 VAPA_1c21890 e57df96ef497dac834fbd9486b892ade 380 Gene3D G3DSA:2.40.110.10 119 232 2.2E-37 T 12-10-2018 VAPA_1c21890 e57df96ef497dac834fbd9486b892ade 380 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 120 215 3.0E-25 T 12-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 VAPA_1c21890 e57df96ef497dac834fbd9486b892ade 380 Gene3D G3DSA:1.20.140.10 233 379 2.6E-52 T 12-10-2018 VAPA_1c21890 e57df96ef497dac834fbd9486b892ade 380 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 334 353 - T 12-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 VAPA_1c21890 e57df96ef497dac834fbd9486b892ade 380 SUPERFAMILY SSF56645 1 226 9.82E-69 T 12-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 VAPA_2c03070 ba3cac6b805aca0f02e918e8db2c5d33 318 PIRSF PIRSF017082 2 317 3.8E-81 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_2c03070 ba3cac6b805aca0f02e918e8db2c5d33 318 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 44 314 1.9E-82 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_2c03070 ba3cac6b805aca0f02e918e8db2c5d33 318 Gene3D G3DSA:3.40.190.10 120 243 5.8E-108 T 12-10-2018 VAPA_2c03070 ba3cac6b805aca0f02e918e8db2c5d33 318 SUPERFAMILY SSF53850 110 280 6.52E-12 T 12-10-2018 VAPA_2c03070 ba3cac6b805aca0f02e918e8db2c5d33 318 Gene3D G3DSA:3.40.190.150 24 308 5.8E-108 T 12-10-2018 VAPA_1c52750 bbd23a157d3b9732abdac0a52a11a777 180 Pfam PF00583 Acetyltransferase (GNAT) family 66 142 6.6E-11 T 12-10-2018 IPR000182 GNAT domain VAPA_1c52750 bbd23a157d3b9732abdac0a52a11a777 180 SUPERFAMILY SSF55729 11 170 1.8E-27 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase VAPA_1c52750 bbd23a157d3b9732abdac0a52a11a777 180 Gene3D G3DSA:3.40.630.30 11 175 8.2E-37 T 12-10-2018 VAPA_1c52750 bbd23a157d3b9732abdac0a52a11a777 180 TIGRFAM TIGR01575 rimI: ribosomal-protein-alanine acetyltransferase 20 165 2.1E-28 T 12-10-2018 IPR006464 N-acetyltransferase RimI/Ard1 GO:0006474|GO:0016407 VAPA_1c30810 7d96b4d251da33f7296e538af44a3ae8 602 SMART SM00382 388 572 6.0E-16 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c30810 7d96b4d251da33f7296e538af44a3ae8 602 Pfam PF00664 ABC transporter transmembrane region 32 223 2.0E-12 T 12-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 VAPA_1c30810 7d96b4d251da33f7296e538af44a3ae8 602 Gene3D G3DSA:3.40.50.300 346 599 8.3E-62 T 12-10-2018 VAPA_1c30810 7d96b4d251da33f7296e538af44a3ae8 602 Gene3D G3DSA:1.20.1560.10 4 324 6.7E-24 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 VAPA_1c30810 7d96b4d251da33f7296e538af44a3ae8 602 SUPERFAMILY SSF90123 17 309 1.03E-31 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 VAPA_1c30810 7d96b4d251da33f7296e538af44a3ae8 602 ProSitePatterns PS00211 ABC transporters family signature. 496 510 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_1c30810 7d96b4d251da33f7296e538af44a3ae8 602 SUPERFAMILY SSF52540 375 592 4.67E-53 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c30810 7d96b4d251da33f7296e538af44a3ae8 602 Pfam PF00005 ABC transporter 379 526 1.7E-27 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c12030 65dcb3f3ea3d6afde4eec552715751a0 712 ProSitePatterns PS00875 Bacterial type II secretion system protein D signature. 651 684 - T 12-10-2018 IPR004845 Type II secretion system GspD, conserved site GO:0008565 VAPA_1c12030 65dcb3f3ea3d6afde4eec552715751a0 712 Gene3D G3DSA:2.60.40.3500 24 132 9.9E-11 T 12-10-2018 VAPA_1c12030 65dcb3f3ea3d6afde4eec552715751a0 712 TIGRFAM TIGR02515 IV_pilus_PilQ: type IV pilus secretin PilQ 274 705 9.2E-151 T 12-10-2018 IPR013355 Type IV pilus secretin PilQ VAPA_1c12030 65dcb3f3ea3d6afde4eec552715751a0 712 Gene3D G3DSA:3.55.50.30 274 344 3.8E-9 T 12-10-2018 VAPA_1c12030 65dcb3f3ea3d6afde4eec552715751a0 712 SMART SM00965 299 347 1.6E-6 T 12-10-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 VAPA_1c12030 65dcb3f3ea3d6afde4eec552715751a0 712 Pfam PF11741 AMIN domain 168 256 5.0E-5 T 12-10-2018 IPR021731 AMIN domain VAPA_1c12030 65dcb3f3ea3d6afde4eec552715751a0 712 Pfam PF11741 AMIN domain 46 129 4.5E-11 T 12-10-2018 IPR021731 AMIN domain VAPA_1c12030 65dcb3f3ea3d6afde4eec552715751a0 712 PRINTS PR00811 Bacterial general secretion pathway protein D signature 449 459 2.6E-19 T 12-10-2018 IPR001775 GspD/PilQ family VAPA_1c12030 65dcb3f3ea3d6afde4eec552715751a0 712 PRINTS PR00811 Bacterial general secretion pathway protein D signature 693 707 2.6E-19 T 12-10-2018 IPR001775 GspD/PilQ family VAPA_1c12030 65dcb3f3ea3d6afde4eec552715751a0 712 PRINTS PR00811 Bacterial general secretion pathway protein D signature 547 571 2.6E-19 T 12-10-2018 IPR001775 GspD/PilQ family VAPA_1c12030 65dcb3f3ea3d6afde4eec552715751a0 712 PRINTS PR00811 Bacterial general secretion pathway protein D signature 670 688 2.6E-19 T 12-10-2018 IPR001775 GspD/PilQ family VAPA_1c12030 65dcb3f3ea3d6afde4eec552715751a0 712 Pfam PF03958 Bacterial type II/III secretion system short domain 372 449 5.0E-14 T 12-10-2018 IPR005644 NolW-like VAPA_1c12030 65dcb3f3ea3d6afde4eec552715751a0 712 Gene3D G3DSA:3.30.1370.120 345 450 3.9E-22 T 12-10-2018 IPR038591 NolW-like superfamily VAPA_1c12030 65dcb3f3ea3d6afde4eec552715751a0 712 Gene3D G3DSA:2.60.40.3470 133 261 4.3E-37 T 12-10-2018 VAPA_1c12030 65dcb3f3ea3d6afde4eec552715751a0 712 Pfam PF00263 Bacterial type II and III secretion system protein 551 705 3.1E-45 T 12-10-2018 IPR004846 Type II/III secretion system GO:0009306 VAPA_1c47150 852667041492116456b3d87145a47595 771 Pfam PF00593 TonB dependent receptor 283 768 1.0E-41 T 12-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel VAPA_1c47150 852667041492116456b3d87145a47595 771 Gene3D G3DSA:2.40.170.20 45 771 4.1E-126 T 12-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily VAPA_1c47150 852667041492116456b3d87145a47595 771 SUPERFAMILY SSF56935 32 770 5.92E-103 T 12-10-2018 VAPA_1c47150 852667041492116456b3d87145a47595 771 Pfam PF07715 TonB-dependent Receptor Plug Domain 54 160 6.1E-14 T 12-10-2018 IPR012910 TonB-dependent receptor, plug domain VAPA_1c53360 0070c99843ba9790badb4ecbe5a64fe1 339 Gene3D G3DSA:3.90.25.10 184 320 4.2E-106 T 12-10-2018 VAPA_1c53360 0070c99843ba9790badb4ecbe5a64fe1 339 SUPERFAMILY SSF51735 1 325 9.35E-46 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c53360 0070c99843ba9790badb4ecbe5a64fe1 339 Gene3D G3DSA:3.40.50.720 8 311 4.2E-106 T 12-10-2018 VAPA_1c53360 0070c99843ba9790badb4ecbe5a64fe1 339 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 212 9.1E-23 T 12-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 VAPA_1c09800 b54dbdcceeea7b3426214171c50a366e 344 Gene3D G3DSA:1.10.10.10 39 127 4.4E-20 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c09800 b54dbdcceeea7b3426214171c50a366e 344 Gene3D G3DSA:3.40.190.10 138 328 2.9E-31 T 12-10-2018 VAPA_1c09800 b54dbdcceeea7b3426214171c50a366e 344 SUPERFAMILY SSF53850 128 339 2.71E-15 T 12-10-2018 VAPA_1c09800 b54dbdcceeea7b3426214171c50a366e 344 Pfam PF03466 LysR substrate binding domain 126 335 1.2E-14 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_1c09800 b54dbdcceeea7b3426214171c50a366e 344 SUPERFAMILY SSF46785 37 149 3.77E-19 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c09800 b54dbdcceeea7b3426214171c50a366e 344 Gene3D G3DSA:3.40.190.10 203 313 2.9E-31 T 12-10-2018 VAPA_1c09800 b54dbdcceeea7b3426214171c50a366e 344 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 41 98 3.2E-18 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c39410 5bf49462be2a4c8fe10c9c9c518658cc 269 Gene3D G3DSA:3.30.450.40 74 253 2.1E-53 T 12-10-2018 IPR029016 GAF-like domain superfamily VAPA_1c39410 5bf49462be2a4c8fe10c9c9c518658cc 269 Pfam PF01614 Bacterial transcriptional regulator 121 244 2.7E-27 T 12-10-2018 IPR014757 Transcription regulator IclR, C-terminal VAPA_1c39410 5bf49462be2a4c8fe10c9c9c518658cc 269 SUPERFAMILY SSF46785 4 73 9.38E-16 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c39410 5bf49462be2a4c8fe10c9c9c518658cc 269 Pfam PF09339 IclR helix-turn-helix domain 4 55 1.8E-14 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 VAPA_1c39410 5bf49462be2a4c8fe10c9c9c518658cc 269 Gene3D G3DSA:1.10.10.10 3 73 1.5E-18 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c39410 5bf49462be2a4c8fe10c9c9c518658cc 269 SMART SM00346 2 92 9.0E-16 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 VAPA_1c39410 5bf49462be2a4c8fe10c9c9c518658cc 269 SUPERFAMILY SSF55781 67 249 2.42E-45 T 12-10-2018 VAPA_1c23500 b910716c0637ca90d2e44ffff0816438 637 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 4 58 3.5E-22 T 12-10-2018 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857 VAPA_1c23500 b910716c0637ca90d2e44ffff0816438 637 Pfam PF00501 AMP-binding enzyme 60 508 3.7E-82 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 VAPA_1c23500 b910716c0637ca90d2e44ffff0816438 637 TIGRFAM TIGR02316 propion_prpE: propionate--CoA ligase 3 634 0.0 T 12-10-2018 IPR012694 Propionate--CoA ligase GO:0019629|GO:0050218 KEGG: 00640+6.2.1.17|MetaCyc: PWY-3941|MetaCyc: PWY-5104|MetaCyc: PWY-5747 VAPA_1c23500 b910716c0637ca90d2e44ffff0816438 637 SUPERFAMILY SSF56801 4 629 1.44E-159 T 12-10-2018 VAPA_1c23500 b910716c0637ca90d2e44ffff0816438 637 Pfam PF13193 AMP-binding enzyme C-terminal domain 517 600 2.4E-23 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain VAPA_1c23500 b910716c0637ca90d2e44ffff0816438 637 Gene3D G3DSA:3.40.50.12780 32 501 4.2E-100 T 12-10-2018 VAPA_1c23500 b910716c0637ca90d2e44ffff0816438 637 Gene3D G3DSA:3.30.300.30 504 637 2.8E-26 T 12-10-2018 VAPA_1c37700 fb368bdb1173c8bbb620ea90daf13e71 70 Gene3D G3DSA:1.10.720.30 1 55 5.5E-26 T 12-10-2018 IPR036361 SAP domain superfamily VAPA_1c37700 fb368bdb1173c8bbb620ea90daf13e71 70 Pfam PF09905 DNA-binding protein VF530 1 50 4.9E-25 T 12-10-2018 IPR018668 DNA-binding protein VF530-like GO:0003677 VAPA_2c12080 79e1e02d9c73f8f15876e24a79355016 111 SUPERFAMILY SSF111352 13 76 4.45E-5 T 12-10-2018 VAPA_2c12080 79e1e02d9c73f8f15876e24a79355016 111 Pfam PF02656 Domain of unknown function (DUF202) 9 72 1.9E-11 T 12-10-2018 IPR003807 Domain of unknown function DUF202 VAPA_1c07890 447534ddbc1bc3cbb6faaac4296f0195 336 Gene3D G3DSA:3.90.180.10 22 333 1.0E-102 T 12-10-2018 VAPA_1c07890 447534ddbc1bc3cbb6faaac4296f0195 336 SUPERFAMILY SSF50129 10 150 2.89E-35 T 12-10-2018 IPR011032 GroES-like superfamily VAPA_1c07890 447534ddbc1bc3cbb6faaac4296f0195 336 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 149 170 - T 12-10-2018 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 VAPA_1c07890 447534ddbc1bc3cbb6faaac4296f0195 336 Pfam PF13602 Zinc-binding dehydrogenase 193 333 9.5E-20 T 12-10-2018 VAPA_1c07890 447534ddbc1bc3cbb6faaac4296f0195 336 TIGRFAM TIGR02817 adh_fam_1: zinc-binding alcohol dehydrogenase family protein 2 336 2.8E-157 T 12-10-2018 IPR014182 Alcohol dehydrogenase, zinc-binding type 1 GO:0008270 VAPA_1c07890 447534ddbc1bc3cbb6faaac4296f0195 336 SMART SM00829 13 333 1.9E-10 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 VAPA_1c07890 447534ddbc1bc3cbb6faaac4296f0195 336 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 31 90 7.5E-9 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 VAPA_1c07890 447534ddbc1bc3cbb6faaac4296f0195 336 SUPERFAMILY SSF51735 117 282 2.3E-35 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c07890 447534ddbc1bc3cbb6faaac4296f0195 336 Gene3D G3DSA:3.40.50.720 128 272 1.0E-102 T 12-10-2018 VAPA_1c15130 32cd47615ec7fe80f0c59bc630b2a4de 362 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 2 351 3.0E-134 T 12-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 VAPA_1c15130 32cd47615ec7fe80f0c59bc630b2a4de 362 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 242 261 - T 12-10-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 VAPA_1c15130 32cd47615ec7fe80f0c59bc630b2a4de 362 SUPERFAMILY SSF53659 1 357 9.02E-124 T 12-10-2018 VAPA_1c15130 32cd47615ec7fe80f0c59bc630b2a4de 362 SMART SM01329 2 351 1.2E-206 T 12-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 VAPA_1c15130 32cd47615ec7fe80f0c59bc630b2a4de 362 Gene3D G3DSA:3.40.718.10 1 355 1.2E-158 T 12-10-2018 VAPA_1c15130 32cd47615ec7fe80f0c59bc630b2a4de 362 Hamap MF_01033 3-isopropylmalate dehydrogenase [leuB]. 1 355 50.942 T 12-10-2018 IPR004429 Isopropylmalate dehydrogenase GO:0003862|GO:0005737|GO:0009098|GO:0055114 KEGG: 00290+1.1.1.85|KEGG: 00660+1.1.1.85|MetaCyc: PWY-7396 VAPA_1c15130 32cd47615ec7fe80f0c59bc630b2a4de 362 TIGRFAM TIGR00169 leuB: 3-isopropylmalate dehydrogenase 2 350 6.3E-152 T 12-10-2018 IPR004429 Isopropylmalate dehydrogenase GO:0003862|GO:0005737|GO:0009098|GO:0055114 KEGG: 00290+1.1.1.85|KEGG: 00660+1.1.1.85|MetaCyc: PWY-7396 VAPA_1c41150 67e9f3b5d81bb560433cd4ab80bf94a0 433 Gene3D G3DSA:3.50.50.60 1 71 8.8E-14 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c41150 67e9f3b5d81bb560433cd4ab80bf94a0 433 Pfam PF01266 FAD dependent oxidoreductase 2 398 3.5E-74 T 12-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 VAPA_1c41150 67e9f3b5d81bb560433cd4ab80bf94a0 433 SUPERFAMILY SSF51905 1 417 4.66E-55 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c41150 67e9f3b5d81bb560433cd4ab80bf94a0 433 Hamap MF_01202 D-amino acid dehydrogenase [dadA]. 1 411 48.562 T 12-10-2018 IPR023080 D-amino acid dehydrogenase DadA GO:0008718|GO:0019478|GO:0055114 VAPA_1c41150 67e9f3b5d81bb560433cd4ab80bf94a0 433 Gene3D G3DSA:3.30.9.10 134 362 1.4E-55 T 12-10-2018 VAPA_1c41150 67e9f3b5d81bb560433cd4ab80bf94a0 433 Gene3D G3DSA:3.50.50.60 104 405 1.4E-55 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c41150 67e9f3b5d81bb560433cd4ab80bf94a0 433 SUPERFAMILY SSF54373 271 360 2.09E-18 T 12-10-2018 VAPA_1c04670 4de5ff01f3704214386f0640705c6494 237 SUPERFAMILY SSF52172 1 177 2.14E-28 T 12-10-2018 IPR011006 CheY-like superfamily VAPA_1c04670 4de5ff01f3704214386f0640705c6494 237 Gene3D G3DSA:1.10.10.10 128 232 3.4E-24 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c04670 4de5ff01f3704214386f0640705c6494 237 SMART SM00448 1 113 4.1E-24 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_1c04670 4de5ff01f3704214386f0640705c6494 237 Pfam PF00072 Response regulator receiver domain 3 114 2.8E-18 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_1c04670 4de5ff01f3704214386f0640705c6494 237 Pfam PF00486 Transcriptional regulatory protein, C terminal 147 223 7.0E-18 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 VAPA_1c04670 4de5ff01f3704214386f0640705c6494 237 SMART SM00862 147 223 4.8E-21 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 VAPA_1c04670 4de5ff01f3704214386f0640705c6494 237 Gene3D G3DSA:3.40.50.2300 1 127 4.0E-27 T 12-10-2018 VAPA_2c01840 752773cfac840c401d5deb32c5f16c26 339 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 32 94 5.3E-11 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 VAPA_2c01840 752773cfac840c401d5deb32c5f16c26 339 SUPERFAMILY SSF51735 132 301 1.77E-29 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_2c01840 752773cfac840c401d5deb32c5f16c26 339 Gene3D G3DSA:3.90.180.10 15 327 3.6E-82 T 12-10-2018 VAPA_2c01840 752773cfac840c401d5deb32c5f16c26 339 SMART SM00829 14 331 3.4E-17 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 VAPA_2c01840 752773cfac840c401d5deb32c5f16c26 339 Gene3D G3DSA:3.40.50.720 131 277 3.6E-82 T 12-10-2018 VAPA_2c01840 752773cfac840c401d5deb32c5f16c26 339 SUPERFAMILY SSF50129 3 154 3.8E-34 T 12-10-2018 IPR011032 GroES-like superfamily VAPA_2c01840 752773cfac840c401d5deb32c5f16c26 339 Pfam PF00107 Zinc-binding dehydrogenase 158 273 9.9E-22 T 12-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 VAPA_1c20100 c24de9feaa3aad1707eb8ac778ce104c 77 PIRSF PIRSF037031 1 77 6.1E-29 T 12-10-2018 IPR005243 Redox-active disulphide protein 2 VAPA_1c20100 c24de9feaa3aad1707eb8ac778ce104c 77 Gene3D G3DSA:3.40.30.10 1 75 3.3E-26 T 12-10-2018 VAPA_1c20100 c24de9feaa3aad1707eb8ac778ce104c 77 SUPERFAMILY SSF52833 2 75 7.24E-19 T 12-10-2018 IPR036249 Thioredoxin-like superfamily VAPA_1c20100 c24de9feaa3aad1707eb8ac778ce104c 77 Pfam PF13192 Thioredoxin domain 1 75 2.0E-26 T 12-10-2018 IPR012336 Thioredoxin-like fold VAPA_2c11340 2ac7fe0cec28e54757e5769602ffce8e 144 SUPERFAMILY SSF46785 5 139 1.93E-27 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_2c11340 2ac7fe0cec28e54757e5769602ffce8e 144 Gene3D G3DSA:1.10.10.10 1 143 8.6E-32 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_2c11340 2ac7fe0cec28e54757e5769602ffce8e 144 SMART SM00347 27 127 6.7E-11 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 VAPA_2c11340 2ac7fe0cec28e54757e5769602ffce8e 144 Pfam PF12802 MarR family 35 91 5.7E-11 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 VAPA_1c16190 cf523f8513406877d9e397dc8d5ddc5a 422 Pfam PF13400 Putative Flp pilus-assembly TadE/G-like 12 58 1.7E-11 T 12-10-2018 IPR028087 Putative Flp pilus-assembly TadG-like, N-terminal VAPA_1c23330 656ad37af722cde664b02a12e391da13 357 TIGRFAM TIGR01036 pyrD_sub2: dihydroorotate dehydrogenase (fumarate) 9 350 2.0E-117 T 12-10-2018 IPR005719 Dihydroorotate dehydrogenase, class 2 GO:0004152|GO:0006207|GO:0016020|GO:0055114 KEGG: 00240+1.3.5.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 VAPA_1c23330 656ad37af722cde664b02a12e391da13 357 Hamap MF_00225 Dihydroorotate dehydrogenase (quinone) [pyrD]. 8 350 48.885 T 12-10-2018 IPR005719 Dihydroorotate dehydrogenase, class 2 GO:0004152|GO:0006207|GO:0016020|GO:0055114 KEGG: 00240+1.3.5.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 VAPA_1c23330 656ad37af722cde664b02a12e391da13 357 ProSitePatterns PS00911 Dihydroorotate dehydrogenase signature 1. 86 105 - T 12-10-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 VAPA_1c23330 656ad37af722cde664b02a12e391da13 357 SUPERFAMILY SSF51395 9 350 1.94E-103 T 12-10-2018 VAPA_1c23330 656ad37af722cde664b02a12e391da13 357 Pfam PF01180 Dihydroorotate dehydrogenase 53 350 1.7E-85 T 12-10-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 VAPA_1c23330 656ad37af722cde664b02a12e391da13 357 Gene3D G3DSA:3.20.20.70 8 349 1.7E-131 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 VAPA_1c23330 656ad37af722cde664b02a12e391da13 357 ProSitePatterns PS00912 Dihydroorotate dehydrogenase signature 2. 306 326 - T 12-10-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 VAPA_1c05320 c3b87fab5cefd00128458e7c442534c9 246 Pfam PF01614 Bacterial transcriptional regulator 182 243 5.1E-9 T 12-10-2018 IPR014757 Transcription regulator IclR, C-terminal VAPA_1c05320 c3b87fab5cefd00128458e7c442534c9 246 SUPERFAMILY SSF46785 22 91 5.37E-14 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c05320 c3b87fab5cefd00128458e7c442534c9 246 Pfam PF09339 IclR helix-turn-helix domain 22 72 5.1E-12 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 VAPA_1c05320 c3b87fab5cefd00128458e7c442534c9 246 Gene3D G3DSA:1.10.10.10 4 80 1.9E-18 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c05320 c3b87fab5cefd00128458e7c442534c9 246 SUPERFAMILY SSF55781 90 245 4.32E-25 T 12-10-2018 VAPA_1c05320 c3b87fab5cefd00128458e7c442534c9 246 Gene3D G3DSA:3.30.450.40 86 245 2.0E-25 T 12-10-2018 IPR029016 GAF-like domain superfamily VAPA_1c05320 c3b87fab5cefd00128458e7c442534c9 246 SMART SM00346 20 109 4.6E-12 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 VAPA_1c53250 d9df27b7be7207ce1009407c84fdacad 277 Gene3D G3DSA:1.10.3720.10 64 264 1.9E-18 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c53250 d9df27b7be7207ce1009407c84fdacad 277 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 88 262 1.9E-20 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 VAPA_1c53250 d9df27b7be7207ce1009407c84fdacad 277 SUPERFAMILY SSF161098 66 253 1.96E-22 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c51260 55d39035d4e8016635a704e3af360ec8 282 PIRSF PIRSF000105 1 282 2.7E-86 T 12-10-2018 IPR022694 3-hydroxyacyl-CoA dehydrogenase GO:0003857|GO:0006631|GO:0055114|GO:0070403 VAPA_1c51260 55d39035d4e8016635a704e3af360ec8 282 ProSitePatterns PS00067 3-hydroxyacyl-CoA dehydrogenase signature. 183 207 - T 12-10-2018 IPR006180 3-hydroxyacyl-CoA dehydrogenase, conserved site GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 VAPA_1c51260 55d39035d4e8016635a704e3af360ec8 282 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 5 183 1.4E-63 T 12-10-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 VAPA_1c51260 55d39035d4e8016635a704e3af360ec8 282 SUPERFAMILY SSF51735 1 185 3.85E-59 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c51260 55d39035d4e8016635a704e3af360ec8 282 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 186 282 2.1E-35 T 12-10-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 VAPA_1c51260 55d39035d4e8016635a704e3af360ec8 282 Gene3D G3DSA:1.10.1040.10 193 278 1.6E-35 T 12-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 VAPA_1c51260 55d39035d4e8016635a704e3af360ec8 282 SUPERFAMILY SSF48179 185 282 1.45E-33 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 VAPA_1c51260 55d39035d4e8016635a704e3af360ec8 282 Gene3D G3DSA:3.40.50.720 1 189 2.3E-72 T 12-10-2018 VAPA_1c53410 84eba1584398c795289ea9ffcbafdbcc 161 SMART SM00344 3 112 1.2E-42 T 12-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 VAPA_1c53410 84eba1584398c795289ea9ffcbafdbcc 161 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 30 49 5.4E-13 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 VAPA_1c53410 84eba1584398c795289ea9ffcbafdbcc 161 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 19 30 5.4E-13 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 VAPA_1c53410 84eba1584398c795289ea9ffcbafdbcc 161 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 3 19 5.4E-13 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 VAPA_1c53410 84eba1584398c795289ea9ffcbafdbcc 161 SUPERFAMILY SSF46785 2 62 1.17E-15 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c53410 84eba1584398c795289ea9ffcbafdbcc 161 Gene3D G3DSA:1.10.10.10 4 55 9.7E-24 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c53410 84eba1584398c795289ea9ffcbafdbcc 161 Pfam PF01037 Lrp/AsnC ligand binding domain 70 143 4.0E-25 T 12-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain VAPA_1c53410 84eba1584398c795289ea9ffcbafdbcc 161 Pfam PF13412 Winged helix-turn-helix DNA-binding 3 49 5.5E-18 T 12-10-2018 VAPA_1c53410 84eba1584398c795289ea9ffcbafdbcc 161 Gene3D G3DSA:3.30.70.920 57 140 3.4E-28 T 12-10-2018 VAPA_1c53410 84eba1584398c795289ea9ffcbafdbcc 161 SUPERFAMILY SSF54909 63 152 4.56E-22 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel VAPA_1c10590 00d84097925a9898f1b8973da2f0d066 161 Pfam PF01037 Lrp/AsnC ligand binding domain 76 149 1.1E-13 T 12-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain VAPA_1c10590 00d84097925a9898f1b8973da2f0d066 161 Gene3D G3DSA:3.30.70.920 65 147 8.5E-16 T 12-10-2018 VAPA_1c10590 00d84097925a9898f1b8973da2f0d066 161 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 6 22 5.2E-10 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 VAPA_1c10590 00d84097925a9898f1b8973da2f0d066 161 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 33 52 5.2E-10 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 VAPA_1c10590 00d84097925a9898f1b8973da2f0d066 161 Pfam PF13404 AsnC-type helix-turn-helix domain 6 47 3.8E-15 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 VAPA_1c10590 00d84097925a9898f1b8973da2f0d066 161 SUPERFAMILY SSF46785 6 64 2.69E-13 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c10590 00d84097925a9898f1b8973da2f0d066 161 Gene3D G3DSA:1.10.10.10 1 60 1.2E-18 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c10590 00d84097925a9898f1b8973da2f0d066 161 SUPERFAMILY SSF54909 71 152 1.61E-12 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel VAPA_1c10590 00d84097925a9898f1b8973da2f0d066 161 SMART SM00344 6 119 2.3E-24 T 12-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 VAPA_2c05840 9ae70293e480023557d6155455cfe810 448 PRINTS PR00149 Fumarate lyase superfamily signature 102 120 5.4E-20 T 12-10-2018 IPR000362 Fumarate lyase family VAPA_2c05840 9ae70293e480023557d6155455cfe810 448 PRINTS PR00149 Fumarate lyase superfamily signature 232 259 5.4E-20 T 12-10-2018 IPR000362 Fumarate lyase family VAPA_2c05840 9ae70293e480023557d6155455cfe810 448 PRINTS PR00149 Fumarate lyase superfamily signature 277 293 5.4E-20 T 12-10-2018 IPR000362 Fumarate lyase family VAPA_2c05840 9ae70293e480023557d6155455cfe810 448 PRINTS PR00149 Fumarate lyase superfamily signature 147 165 5.4E-20 T 12-10-2018 IPR000362 Fumarate lyase family VAPA_2c05840 9ae70293e480023557d6155455cfe810 448 Gene3D G3DSA:1.10.275.10 4 106 8.0E-34 T 12-10-2018 IPR024083 Fumarase/histidase, N-terminal VAPA_2c05840 9ae70293e480023557d6155455cfe810 448 Pfam PF00206 Lyase 19 290 1.9E-43 T 12-10-2018 IPR022761 Fumarate lyase, N-terminal VAPA_2c05840 9ae70293e480023557d6155455cfe810 448 Gene3D G3DSA:1.10.40.30 364 448 1.3E-29 T 12-10-2018 VAPA_2c05840 9ae70293e480023557d6155455cfe810 448 PRINTS PR00145 Argininosuccinate lyase family signature 277 293 1.4E-5 T 12-10-2018 VAPA_2c05840 9ae70293e480023557d6155455cfe810 448 PRINTS PR00145 Argininosuccinate lyase family signature 142 162 1.4E-5 T 12-10-2018 VAPA_2c05840 9ae70293e480023557d6155455cfe810 448 PRINTS PR00145 Argininosuccinate lyase family signature 232 256 1.4E-5 T 12-10-2018 VAPA_2c05840 9ae70293e480023557d6155455cfe810 448 SMART SM00998 365 444 5.6E-29 T 12-10-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 VAPA_2c05840 9ae70293e480023557d6155455cfe810 448 Gene3D G3DSA:1.20.200.10 107 362 2.3E-88 T 12-10-2018 VAPA_2c05840 9ae70293e480023557d6155455cfe810 448 Pfam PF10397 Adenylosuccinate lyase C-terminus 366 443 9.1E-21 T 12-10-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 VAPA_2c05840 9ae70293e480023557d6155455cfe810 448 SUPERFAMILY SSF48557 11 445 3.77E-112 T 12-10-2018 IPR008948 L-Aspartase-like GO:0003824 VAPA_2c11150 f3446a872fb55c08ed359babd9656be9 606 Gene3D G3DSA:1.10.287.130 211 291 1.3E-12 T 12-10-2018 VAPA_2c11150 f3446a872fb55c08ed359babd9656be9 606 SUPERFAMILY SSF47384 207 289 1.2E-12 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 VAPA_2c11150 f3446a872fb55c08ed359babd9656be9 606 SMART SM00388 224 289 1.6E-12 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 VAPA_2c11150 f3446a872fb55c08ed359babd9656be9 606 SUPERFAMILY SSF55874 278 443 4.58E-41 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_2c11150 f3446a872fb55c08ed359babd9656be9 606 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 334 443 9.9E-26 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase VAPA_2c11150 f3446a872fb55c08ed359babd9656be9 606 Pfam PF00512 His Kinase A (phospho-acceptor) domain 225 289 3.2E-10 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 VAPA_2c11150 f3446a872fb55c08ed359babd9656be9 606 Gene3D G3DSA:3.30.565.10 299 449 7.9E-38 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_2c11150 f3446a872fb55c08ed359babd9656be9 606 SMART SM00448 473 590 3.1E-12 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_2c11150 f3446a872fb55c08ed359babd9656be9 606 Gene3D G3DSA:3.40.50.2300 473 596 1.3E-18 T 12-10-2018 VAPA_2c11150 f3446a872fb55c08ed359babd9656be9 606 SUPERFAMILY SSF52172 475 594 5.98E-19 T 12-10-2018 IPR011006 CheY-like superfamily VAPA_2c11150 f3446a872fb55c08ed359babd9656be9 606 Pfam PF00072 Response regulator receiver domain 475 590 1.8E-12 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_2c11150 f3446a872fb55c08ed359babd9656be9 606 PRINTS PR00344 Bacterial sensor protein C-terminal signature 369 383 1.9E-12 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_2c11150 f3446a872fb55c08ed359babd9656be9 606 PRINTS PR00344 Bacterial sensor protein C-terminal signature 387 397 1.9E-12 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_2c11150 f3446a872fb55c08ed359babd9656be9 606 PRINTS PR00344 Bacterial sensor protein C-terminal signature 428 441 1.9E-12 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_2c11150 f3446a872fb55c08ed359babd9656be9 606 PRINTS PR00344 Bacterial sensor protein C-terminal signature 404 422 1.9E-12 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_2c11150 f3446a872fb55c08ed359babd9656be9 606 SMART SM00387 333 444 2.3E-32 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase VAPA_1c16100 2f696f95759e17e660966ebb17f1adbd 296 SUPERFAMILY SSF56672 60 232 9.45E-28 T 12-10-2018 VAPA_1c16100 2f696f95759e17e660966ebb17f1adbd 296 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 112 218 4.6E-20 T 12-10-2018 IPR000477 Reverse transcriptase domain VAPA_1c01100 8d063118aeb649809bd496739e311ef0 260 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_1c01100 8d063118aeb649809bd496739e311ef0 260 SUPERFAMILY SSF52540 8 215 1.3E-61 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c01100 8d063118aeb649809bd496739e311ef0 260 Pfam PF00005 ABC transporter 24 164 6.8E-27 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c01100 8d063118aeb649809bd496739e311ef0 260 SMART SM00382 32 214 2.5E-14 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c01100 8d063118aeb649809bd496739e311ef0 260 Gene3D G3DSA:3.40.50.300 6 251 3.8E-59 T 12-10-2018 VAPA_2c11730 f1b528deb926688b537f72cbb01bc5cb 327 Gene3D G3DSA:3.40.190.10 126 306 2.7E-72 T 12-10-2018 VAPA_2c11730 f1b528deb926688b537f72cbb01bc5cb 327 Gene3D G3DSA:3.40.190.10 29 293 2.7E-72 T 12-10-2018 VAPA_2c11730 f1b528deb926688b537f72cbb01bc5cb 327 SUPERFAMILY SSF53850 24 322 1.03E-64 T 12-10-2018 VAPA_2c11730 f1b528deb926688b537f72cbb01bc5cb 327 Pfam PF13343 Bacterial extracellular solute-binding protein 74 295 9.6E-30 T 12-10-2018 VAPA_2c11730 f1b528deb926688b537f72cbb01bc5cb 327 PIRSF PIRSF002825 17 325 1.3E-86 T 12-10-2018 IPR026045 Ferric binding protein VAPA_1c52300 59c3b5630f4feb38830ddb235ca0ea81 158 Pfam PF01047 MarR family 43 100 4.4E-10 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 VAPA_1c52300 59c3b5630f4feb38830ddb235ca0ea81 158 ProSitePatterns PS01117 MarR-type HTH domain signature. 75 109 - T 12-10-2018 IPR023187 Transcriptional regulator MarR-type, conserved site VAPA_1c52300 59c3b5630f4feb38830ddb235ca0ea81 158 PRINTS PR00598 Bacterial regulatory protein MarR family signature 126 146 3.2E-13 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 VAPA_1c52300 59c3b5630f4feb38830ddb235ca0ea81 158 PRINTS PR00598 Bacterial regulatory protein MarR family signature 96 112 3.2E-13 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 VAPA_1c52300 59c3b5630f4feb38830ddb235ca0ea81 158 PRINTS PR00598 Bacterial regulatory protein MarR family signature 60 76 3.2E-13 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 VAPA_1c52300 59c3b5630f4feb38830ddb235ca0ea81 158 PRINTS PR00598 Bacterial regulatory protein MarR family signature 77 92 3.2E-13 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 VAPA_1c52300 59c3b5630f4feb38830ddb235ca0ea81 158 Gene3D G3DSA:1.10.10.10 3 152 2.6E-36 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c52300 59c3b5630f4feb38830ddb235ca0ea81 158 SMART SM00347 35 136 8.5E-22 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 VAPA_1c52300 59c3b5630f4feb38830ddb235ca0ea81 158 SUPERFAMILY SSF46785 13 148 8.24E-31 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c40260 4826d8ed136ee893e41d6517278af227 816 SUPERFAMILY SSF56003 169 811 2.09E-196 T 12-10-2018 IPR037165 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain superfamily GO:0016491|GO:0055114 VAPA_1c40260 4826d8ed136ee893e41d6517278af227 816 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 57 159 3.4E-19 T 12-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead VAPA_1c40260 4826d8ed136ee893e41d6517278af227 816 Gene3D G3DSA:3.30.365.10 227 321 9.5E-269 T 12-10-2018 VAPA_1c40260 4826d8ed136ee893e41d6517278af227 816 Gene3D G3DSA:3.30.365.10 170 809 9.5E-269 T 12-10-2018 VAPA_1c40260 4826d8ed136ee893e41d6517278af227 816 SMART SM01008 56 169 3.3E-36 T 12-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead VAPA_1c40260 4826d8ed136ee893e41d6517278af227 816 TIGRFAM TIGR02965 xanthine_xdhB: xanthine dehydrogenase, molybdopterin binding subunit 42 814 0.0 T 12-10-2018 IPR014309 Xanthine dehydrogenase, molybdopterin binding subunit GO:0030151 KEGG: 00230+1.17.1.4+1.17.3.2|KEGG: 00232+1.17.3.2|KEGG: 00983+1.17.3.2|MetaCyc: PWY-5497|MetaCyc: PWY-5695|MetaCyc: PWY-6538|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-6999 VAPA_1c40260 4826d8ed136ee893e41d6517278af227 816 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 199 743 1.7E-197 T 12-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 VAPA_1c40260 4826d8ed136ee893e41d6517278af227 816 Gene3D G3DSA:3.30.365.10 183 446 9.5E-269 T 12-10-2018 VAPA_1c40260 4826d8ed136ee893e41d6517278af227 816 Gene3D G3DSA:3.30.365.10 498 644 9.5E-269 T 12-10-2018 VAPA_1c40260 4826d8ed136ee893e41d6517278af227 816 Gene3D G3DSA:3.90.1170.50 42 169 9.5E-269 T 12-10-2018 VAPA_1c40260 4826d8ed136ee893e41d6517278af227 816 SUPERFAMILY SSF54665 41 159 4.84E-33 T 12-10-2018 IPR036856 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead superfamily VAPA_1c49110 1837546f94310f342af31604ee57d87d 195 Gene3D G3DSA:3.40.50.360 1 194 1.6E-40 T 12-10-2018 IPR029039 Flavoprotein-like superfamily VAPA_1c49110 1837546f94310f342af31604ee57d87d 195 SUPERFAMILY SSF52218 1 194 8.38E-45 T 12-10-2018 IPR029039 Flavoprotein-like superfamily VAPA_1c49110 1837546f94310f342af31604ee57d87d 195 Pfam PF02525 Flavodoxin-like fold 1 186 7.7E-31 T 12-10-2018 IPR003680 Flavodoxin-like fold VAPA_1c20820 e56de2938f72b7cfc4584a162df90a9a 351 SMART SM00354 13 83 2.7E-6 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 VAPA_1c20820 e56de2938f72b7cfc4584a162df90a9a 351 ProSitePatterns PS00356 LacI-type HTH domain signature. 16 34 - T 12-10-2018 VAPA_1c20820 e56de2938f72b7cfc4584a162df90a9a 351 Pfam PF13407 Periplasmic binding protein domain 129 331 9.9E-39 T 12-10-2018 IPR025997 Periplasmic binding protein VAPA_1c20820 e56de2938f72b7cfc4584a162df90a9a 351 Gene3D G3DSA:3.40.50.2300 98 341 1.9E-40 T 12-10-2018 VAPA_1c20820 e56de2938f72b7cfc4584a162df90a9a 351 Gene3D G3DSA:1.10.260.40 8 66 4.8E-15 T 12-10-2018 VAPA_1c20820 e56de2938f72b7cfc4584a162df90a9a 351 SUPERFAMILY SSF53822 74 345 3.64E-42 T 12-10-2018 IPR028082 Periplasmic binding protein-like I VAPA_1c20820 e56de2938f72b7cfc4584a162df90a9a 351 Gene3D G3DSA:3.40.50.2300 177 350 1.9E-40 T 12-10-2018 VAPA_1c20820 e56de2938f72b7cfc4584a162df90a9a 351 SUPERFAMILY SSF47413 13 61 4.88E-12 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 VAPA_1c20820 e56de2938f72b7cfc4584a162df90a9a 351 Pfam PF00356 Bacterial regulatory proteins, lacI family 18 59 6.8E-13 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 VAPA_1c26580 fc2adf0b0ca72cde4d2525bd309d5d3b 405 Gene3D G3DSA:1.20.1720.10 10 391 1.2E-98 T 12-10-2018 VAPA_1c26580 fc2adf0b0ca72cde4d2525bd309d5d3b 405 SUPERFAMILY SSF103473 4 392 4.05E-61 T 12-10-2018 IPR036259 MFS transporter superfamily VAPA_1c26580 fc2adf0b0ca72cde4d2525bd309d5d3b 405 TIGRFAM TIGR00710 efflux_Bcr_CflA: drug resistance transporter, Bcr/CflA subfamily 8 385 1.9E-85 T 12-10-2018 IPR004812 Drug resistance transporter Bcr/CmlA subfamily GO:0006855|GO:0015238|GO:0016021 VAPA_1c26580 fc2adf0b0ca72cde4d2525bd309d5d3b 405 Pfam PF07690 Major Facilitator Superfamily 16 358 1.2E-39 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 VAPA_1c01060 f9660ca140e75e2a681342b4e8b14c25 441 TIGRFAM TIGR01266 fum_ac_acetase: fumarylacetoacetase 15 439 1.1E-151 T 12-10-2018 IPR005959 Fumarylacetoacetase GO:0004334|GO:0009072 KEGG: 00350+3.7.1.2|KEGG: 00643+3.7.1.2|Reactome: R-HSA-71182 VAPA_1c01060 f9660ca140e75e2a681342b4e8b14c25 441 SUPERFAMILY SSF63433 14 133 4.58E-29 T 12-10-2018 IPR036462 Fumarylacetoacetase, N-terminal domain superfamily GO:0004334|GO:0009072 KEGG: 00350+3.7.1.2|KEGG: 00643+3.7.1.2|Reactome: R-HSA-71182 VAPA_1c01060 f9660ca140e75e2a681342b4e8b14c25 441 SUPERFAMILY SSF56529 135 439 9.55E-90 T 12-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 VAPA_1c01060 f9660ca140e75e2a681342b4e8b14c25 441 Gene3D G3DSA:2.30.30.230 2 130 2.7E-31 T 12-10-2018 IPR036462 Fumarylacetoacetase, N-terminal domain superfamily GO:0004334|GO:0009072 KEGG: 00350+3.7.1.2|KEGG: 00643+3.7.1.2|Reactome: R-HSA-71182 VAPA_1c01060 f9660ca140e75e2a681342b4e8b14c25 441 Gene3D G3DSA:3.90.850.10 131 441 4.9E-112 T 12-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 VAPA_1c01060 f9660ca140e75e2a681342b4e8b14c25 441 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 139 436 9.4E-55 T 12-10-2018 IPR011234 Fumarylacetoacetase-like, C-terminal GO:0003824 VAPA_1c01060 f9660ca140e75e2a681342b4e8b14c25 441 Pfam PF09298 Fumarylacetoacetase N-terminal 30 133 2.4E-20 T 12-10-2018 IPR015377 Fumarylacetoacetase, N-terminal GO:0004334|GO:0009072 KEGG: 00350+3.7.1.2|KEGG: 00643+3.7.1.2|Reactome: R-HSA-71182 VAPA_1c22570 5964352f1e3f213bf6f9076660229dd1 455 ProSitePatterns PS00570 Bacterial ring hydroxylating dioxygenases alpha-subunit signature. 86 109 - T 12-10-2018 IPR015881 Aromatic-ring-hydroxylating dioxygenase, 2Fe-2S-binding site GO:0005506|GO:0051537|GO:0055114 VAPA_1c22570 5964352f1e3f213bf6f9076660229dd1 455 SUPERFAMILY SSF50022 12 160 2.1E-46 T 12-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 VAPA_1c22570 5964352f1e3f213bf6f9076660229dd1 455 Gene3D G3DSA:3.90.380.10 18 434 1.9E-142 T 12-10-2018 VAPA_1c22570 5964352f1e3f213bf6f9076660229dd1 455 SUPERFAMILY SSF55961 160 442 2.83E-56 T 12-10-2018 VAPA_1c22570 5964352f1e3f213bf6f9076660229dd1 455 Pfam PF00355 Rieske [2Fe-2S] domain 43 127 3.4E-19 T 12-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 VAPA_1c22570 5964352f1e3f213bf6f9076660229dd1 455 Pfam PF00848 Ring hydroxylating alpha subunit (catalytic domain) 167 435 5.7E-25 T 12-10-2018 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0044237|GO:0051537|GO:0055114 VAPA_1c22570 5964352f1e3f213bf6f9076660229dd1 455 Gene3D G3DSA:2.102.10.10 43 172 1.9E-142 T 12-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 VAPA_1c22570 5964352f1e3f213bf6f9076660229dd1 455 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 79 99 4.1E-53 T 12-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 VAPA_1c22570 5964352f1e3f213bf6f9076660229dd1 455 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 58 73 4.1E-53 T 12-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 VAPA_1c22570 5964352f1e3f213bf6f9076660229dd1 455 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 28 53 4.1E-53 T 12-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 VAPA_1c22570 5964352f1e3f213bf6f9076660229dd1 455 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 144 170 4.1E-53 T 12-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 VAPA_1c22570 5964352f1e3f213bf6f9076660229dd1 455 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 188 210 4.1E-53 T 12-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 VAPA_1c22570 5964352f1e3f213bf6f9076660229dd1 455 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 100 120 4.1E-53 T 12-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 VAPA_1c44970 3a9e67d3d31d0b5189f3e951626d2a70 67 TIGRFAM TIGR00690 rpoZ: DNA-directed RNA polymerase, omega subunit 1 57 1.2E-16 T 12-10-2018 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 VAPA_1c44970 3a9e67d3d31d0b5189f3e951626d2a70 67 SUPERFAMILY SSF63562 1 63 2.79E-19 T 12-10-2018 IPR036161 RPB6/omega subunit-like superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 VAPA_1c44970 3a9e67d3d31d0b5189f3e951626d2a70 67 Hamap MF_00366 DNA-directed RNA polymerase subunit omega [rpoZ]. 1 60 15.758 T 12-10-2018 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 VAPA_1c44970 3a9e67d3d31d0b5189f3e951626d2a70 67 Gene3D G3DSA:3.90.940.10 1 66 1.3E-20 T 12-10-2018 IPR012293 RNA polymerase subunit, RPB6/omega GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 VAPA_1c44970 3a9e67d3d31d0b5189f3e951626d2a70 67 Pfam PF01192 RNA polymerase Rpb6 8 59 4.7E-14 T 12-10-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 VAPA_1c44970 3a9e67d3d31d0b5189f3e951626d2a70 67 SMART SM01409 8 59 6.3E-14 T 12-10-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 VAPA_1c10950 f7b8947f63e0926e82936f70013298cf 319 Gene3D G3DSA:1.10.10.10 12 101 1.7E-23 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c10950 f7b8947f63e0926e82936f70013298cf 319 Gene3D G3DSA:3.40.190.10 178 280 3.2E-46 T 12-10-2018 VAPA_1c10950 f7b8947f63e0926e82936f70013298cf 319 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 16 74 3.0E-19 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c10950 f7b8947f63e0926e82936f70013298cf 319 Pfam PF03466 LysR substrate binding domain 101 306 8.4E-34 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_1c10950 f7b8947f63e0926e82936f70013298cf 319 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 51 1.9E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c10950 f7b8947f63e0926e82936f70013298cf 319 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 51 62 1.9E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c10950 f7b8947f63e0926e82936f70013298cf 319 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 41 1.9E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c10950 f7b8947f63e0926e82936f70013298cf 319 SUPERFAMILY SSF46785 11 122 2.3E-24 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c10950 f7b8947f63e0926e82936f70013298cf 319 Gene3D G3DSA:3.40.190.10 105 297 3.2E-46 T 12-10-2018 VAPA_1c10950 f7b8947f63e0926e82936f70013298cf 319 SUPERFAMILY SSF53850 103 307 5.76E-35 T 12-10-2018 VAPA_1c04790 eb62036841fafd5f1b227dc248dd772f 328 SUPERFAMILY SSF144083 262 324 2.22E-20 T 12-10-2018 VAPA_1c04790 eb62036841fafd5f1b227dc248dd772f 328 TIGRFAM TIGR00383 corA: magnesium and cobalt transport protein CorA 3 327 5.2E-70 T 12-10-2018 IPR004488 Magnesium/cobalt transport protein CorA GO:0006824|GO:0015087|GO:0015095|GO:0015693|GO:0016020 VAPA_1c04790 eb62036841fafd5f1b227dc248dd772f 328 Gene3D G3DSA:1.20.58.340 251 327 5.3E-26 T 12-10-2018 VAPA_1c04790 eb62036841fafd5f1b227dc248dd772f 328 SUPERFAMILY SSF143865 1 265 1.18E-36 T 12-10-2018 VAPA_1c04790 eb62036841fafd5f1b227dc248dd772f 328 Pfam PF01544 CorA-like Mg2+ transporter protein 29 323 1.7E-54 T 12-10-2018 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 VAPA_1c20780 622a2dea7eee2fb8ebea3f8e39b61859 423 Pfam PF00016 Ribulose bisphosphate carboxylase large chain, catalytic domain 140 420 1.3E-78 T 12-10-2018 IPR000685 Ribulose bisphosphate carboxylase, large subunit, C-terminal GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 VAPA_1c20780 622a2dea7eee2fb8ebea3f8e39b61859 423 Pfam PF02788 Ribulose bisphosphate carboxylase large chain, N-terminal domain 18 130 1.2E-5 T 12-10-2018 IPR017443 Ribulose bisphosphate carboxylase, large subunit, ferrodoxin-like N-terminal GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 VAPA_1c20780 622a2dea7eee2fb8ebea3f8e39b61859 423 ProSitePatterns PS00157 Ribulose bisphosphate carboxylase large chain active site. 182 190 - T 12-10-2018 IPR020878 Ribulose bisphosphate carboxylase, large chain, active site GO:0000287|GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 VAPA_1c20780 622a2dea7eee2fb8ebea3f8e39b61859 423 Gene3D G3DSA:3.20.20.110 135 423 3.1E-103 T 12-10-2018 IPR036376 Ribulose bisphosphate carboxylase, large subunit, C-terminal domain superfamily GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 VAPA_1c20780 622a2dea7eee2fb8ebea3f8e39b61859 423 SUPERFAMILY SSF54966 4 134 1.57E-34 T 12-10-2018 IPR036422 RuBisCO large subunit, N-terminal domain superfamily GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 VAPA_1c20780 622a2dea7eee2fb8ebea3f8e39b61859 423 SUPERFAMILY SSF51649 137 422 2.88E-90 T 12-10-2018 IPR036376 Ribulose bisphosphate carboxylase, large subunit, C-terminal domain superfamily GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 VAPA_1c20780 622a2dea7eee2fb8ebea3f8e39b61859 423 Gene3D G3DSA:3.30.70.150 1 134 1.2E-43 T 12-10-2018 IPR036422 RuBisCO large subunit, N-terminal domain superfamily GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 VAPA_1c54130 55c29789f7db0d499b2879636d7d2bb0 321 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 44 312 2.0E-77 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c54130 55c29789f7db0d499b2879636d7d2bb0 321 Gene3D G3DSA:3.40.190.10 122 246 1.4E-106 T 12-10-2018 VAPA_1c54130 55c29789f7db0d499b2879636d7d2bb0 321 Gene3D G3DSA:3.40.190.150 26 311 1.4E-106 T 12-10-2018 VAPA_1c54130 55c29789f7db0d499b2879636d7d2bb0 321 SUPERFAMILY SSF53850 113 282 3.47E-7 T 12-10-2018 VAPA_1c54130 55c29789f7db0d499b2879636d7d2bb0 321 PIRSF PIRSF017082 2 319 3.3E-71 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c18490 ada243415c90524a815386322d76c91b 734 Pfam PF04539 Sigma-70 region 3 578 653 4.8E-22 T 12-10-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003700|GO:0006352|GO:0006355 VAPA_1c18490 ada243415c90524a815386322d76c91b 734 Pfam PF04545 Sigma-70, region 4 668 720 1.3E-18 T 12-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 VAPA_1c18490 ada243415c90524a815386322d76c91b 734 Pfam PF03979 Sigma-70 factor, region 1.1 118 197 1.1E-24 T 12-10-2018 IPR007127 RNA polymerase sigma factor 70, region 1.1 GO:0003677|GO:0006355 VAPA_1c18490 ada243415c90524a815386322d76c91b 734 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 495 720 8.3E-41 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 VAPA_1c18490 ada243415c90524a815386322d76c91b 734 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 692 718 - T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 VAPA_1c18490 ada243415c90524a815386322d76c91b 734 SUPERFAMILY SSF88946 231 566 4.24E-102 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 VAPA_1c18490 ada243415c90524a815386322d76c91b 734 TIGRFAM TIGR02393 RpoD_Cterm: RNA polymerase sigma factor RpoD 495 731 7.6E-118 T 12-10-2018 IPR012760 RNA polymerase sigma factor RpoD, C-terminal GO:0003677|GO:0006352|GO:0006355|GO:0016987 VAPA_1c18490 ada243415c90524a815386322d76c91b 734 Gene3D G3DSA:1.10.220.120 117 178 6.5E-23 T 12-10-2018 VAPA_1c18490 ada243415c90524a815386322d76c91b 734 Gene3D G3DSA:1.10.10.10 572 647 3.2E-28 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c18490 ada243415c90524a815386322d76c91b 734 Gene3D G3DSA:1.10.10.10 649 733 6.5E-35 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c18490 ada243415c90524a815386322d76c91b 734 Pfam PF00140 Sigma-70 factor, region 1.2 214 245 1.6E-12 T 12-10-2018 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 VAPA_1c18490 ada243415c90524a815386322d76c91b 734 Pfam PF04542 Sigma-70 region 2 499 568 2.3E-21 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 VAPA_1c18490 ada243415c90524a815386322d76c91b 734 SUPERFAMILY SSF88659 629 731 2.62E-27 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like VAPA_1c18490 ada243415c90524a815386322d76c91b 734 Gene3D G3DSA:1.10.601.10 229 568 3.3E-117 T 12-10-2018 VAPA_1c18490 ada243415c90524a815386322d76c91b 734 Hamap MF_00963 RNA polymerase sigma factor RpoD [rpoD]. 118 732 41.352 T 12-10-2018 IPR028630 RNA polymerase sigma factor RpoD GO:0006352|GO:0016987 VAPA_1c18490 ada243415c90524a815386322d76c91b 734 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 523 536 - T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 VAPA_1c18490 ada243415c90524a815386322d76c91b 734 Pfam PF04546 Sigma-70, non-essential region 256 468 1.2E-59 T 12-10-2018 IPR007631 RNA polymerase sigma factor 70, non-essential domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 VAPA_1c18490 ada243415c90524a815386322d76c91b 734 SUPERFAMILY SSF88659 572 645 1.78E-16 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like VAPA_1c18490 ada243415c90524a815386322d76c91b 734 PRINTS PR00046 Major sigma-70 factor signature 547 555 6.8E-31 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 VAPA_1c18490 ada243415c90524a815386322d76c91b 734 PRINTS PR00046 Major sigma-70 factor signature 671 683 6.8E-31 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 VAPA_1c18490 ada243415c90524a815386322d76c91b 734 PRINTS PR00046 Major sigma-70 factor signature 523 536 6.8E-31 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 VAPA_1c18490 ada243415c90524a815386322d76c91b 734 PRINTS PR00046 Major sigma-70 factor signature 692 707 6.8E-31 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 VAPA_1c18490 ada243415c90524a815386322d76c91b 734 PRINTS PR00046 Major sigma-70 factor signature 707 718 6.8E-31 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 VAPA_1c45890 2fd64dfa3b98599e13f8c966e615e0cc 247 SMART SM00100 27 145 3.2E-14 T 12-10-2018 IPR000595 Cyclic nucleotide-binding domain VAPA_1c45890 2fd64dfa3b98599e13f8c966e615e0cc 247 Gene3D G3DSA:1.10.10.10 162 245 2.7E-12 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c45890 2fd64dfa3b98599e13f8c966e615e0cc 247 SUPERFAMILY SSF46785 163 239 2.4E-11 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c45890 2fd64dfa3b98599e13f8c966e615e0cc 247 Pfam PF13545 Crp-like helix-turn-helix domain 166 237 4.9E-9 T 12-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 VAPA_1c45890 2fd64dfa3b98599e13f8c966e615e0cc 247 Pfam PF00027 Cyclic nucleotide-binding domain 47 132 1.2E-15 T 12-10-2018 IPR000595 Cyclic nucleotide-binding domain VAPA_1c45890 2fd64dfa3b98599e13f8c966e615e0cc 247 SUPERFAMILY SSF51206 22 159 1.44E-27 T 12-10-2018 IPR018490 Cyclic nucleotide-binding-like VAPA_1c45890 2fd64dfa3b98599e13f8c966e615e0cc 247 Gene3D G3DSA:2.60.120.10 18 161 3.1E-28 T 12-10-2018 IPR014710 RmlC-like jelly roll fold VAPA_1c33850 aeb9e6208b3945ed7c1f064e6c542922 464 Gene3D G3DSA:3.20.20.70 142 453 9.8E-145 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 VAPA_1c33850 aeb9e6208b3945ed7c1f064e6c542922 464 Pfam PF06751 Ethanolamine ammonia lyase large subunit (EutB) 12 445 1.0E-219 T 12-10-2018 IPR010628 Ethanolamine ammonia lyase large subunit GO:0006520|GO:0008851 KEGG: 00564+4.3.1.7 VAPA_1c33850 aeb9e6208b3945ed7c1f064e6c542922 464 PIRSF PIRSF018788 1 458 8.1E-234 T 12-10-2018 IPR010628 Ethanolamine ammonia lyase large subunit GO:0006520|GO:0008851 KEGG: 00564+4.3.1.7 VAPA_1c33850 aeb9e6208b3945ed7c1f064e6c542922 464 Gene3D G3DSA:2.30.170.30 1 54 6.9E-20 T 12-10-2018 VAPA_1c33850 aeb9e6208b3945ed7c1f064e6c542922 464 Gene3D G3DSA:1.10.220.70 55 141 6.1E-34 T 12-10-2018 VAPA_1c11670 9b10c81d8255f71241884e613e83c80d 345 Gene3D G3DSA:2.40.50.140 271 328 8.9E-25 T 12-10-2018 VAPA_1c11670 9b10c81d8255f71241884e613e83c80d 345 Gene3D G3DSA:2.40.50.940 222 337 8.9E-25 T 12-10-2018 VAPA_1c11670 9b10c81d8255f71241884e613e83c80d 345 Gene3D G3DSA:3.40.50.300 3 221 9.4E-64 T 12-10-2018 VAPA_1c11670 9b10c81d8255f71241884e613e83c80d 345 SUPERFAMILY SSF50331 237 342 4.54E-21 T 12-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal VAPA_1c11670 9b10c81d8255f71241884e613e83c80d 345 SUPERFAMILY SSF52540 4 242 8.06E-85 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c11670 9b10c81d8255f71241884e613e83c80d 345 SMART SM00382 28 211 7.1E-15 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c11670 9b10c81d8255f71241884e613e83c80d 345 Pfam PF08402 TOBE domain 264 336 2.8E-14 T 12-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 VAPA_1c11670 9b10c81d8255f71241884e613e83c80d 345 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_1c11670 9b10c81d8255f71241884e613e83c80d 345 Pfam PF00005 ABC transporter 20 161 2.2E-31 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c12100 82ba2f4d28e1bd9786da7064e503047b 231 Gene3D G3DSA:3.30.70.1290 1 155 1.3E-39 T 12-10-2018 IPR036515 Transposase IS200-like superfamily GO:0003677|GO:0004803|GO:0006313 VAPA_1c12100 82ba2f4d28e1bd9786da7064e503047b 231 Pfam PF01797 Transposase IS200 like 12 122 4.6E-16 T 12-10-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 VAPA_1c12100 82ba2f4d28e1bd9786da7064e503047b 231 SUPERFAMILY SSF143422 3 127 3.79E-34 T 12-10-2018 IPR036515 Transposase IS200-like superfamily GO:0003677|GO:0004803|GO:0006313 VAPA_1c12100 82ba2f4d28e1bd9786da7064e503047b 231 SMART SM01321 9 124 2.5E-47 T 12-10-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 VAPA_1c23710 153bff803013aec874846cc7f20a083a 447 Gene3D G3DSA:3.40.50.300 1 160 2.4E-44 T 12-10-2018 VAPA_1c23710 153bff803013aec874846cc7f20a083a 447 SUPERFAMILY SSF52540 138 443 3.22E-59 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c23710 153bff803013aec874846cc7f20a083a 447 TIGRFAM TIGR03594 GTPase_EngA: ribosome-associated GTPase EngA 3 436 5.8E-171 T 12-10-2018 IPR016484 GTP-binding protein EngA GO:0005525 VAPA_1c23710 153bff803013aec874846cc7f20a083a 447 Gene3D G3DSA:3.40.50.300 176 354 3.5E-47 T 12-10-2018 VAPA_1c23710 153bff803013aec874846cc7f20a083a 447 Pfam PF14714 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal 356 436 1.9E-23 T 12-10-2018 IPR032859 GTPase Der, C-terminal KH-domain-like VAPA_1c23710 153bff803013aec874846cc7f20a083a 447 Pfam PF01926 50S ribosome-binding GTPase 183 300 4.8E-22 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 VAPA_1c23710 153bff803013aec874846cc7f20a083a 447 Pfam PF01926 50S ribosome-binding GTPase 5 120 1.2E-26 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 VAPA_1c23710 153bff803013aec874846cc7f20a083a 447 Hamap MF_00195 GTPase Der [der]. 2 439 37.781 T 12-10-2018 IPR016484 GTP-binding protein EngA GO:0005525 VAPA_1c23710 153bff803013aec874846cc7f20a083a 447 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 5 25 6.5E-9 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 VAPA_1c23710 153bff803013aec874846cc7f20a083a 447 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 73 91 6.5E-9 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 VAPA_1c23710 153bff803013aec874846cc7f20a083a 447 Gene3D G3DSA:3.30.300.20 356 439 5.1E-19 T 12-10-2018 IPR015946 K homology domain-like, alpha/beta VAPA_1c23710 153bff803013aec874846cc7f20a083a 447 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 4 158 4.5E-21 T 12-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 VAPA_1c23710 153bff803013aec874846cc7f20a083a 447 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 179 334 2.1E-25 T 12-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 VAPA_1c23710 153bff803013aec874846cc7f20a083a 447 SUPERFAMILY SSF52540 4 162 1.04E-47 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c23710 153bff803013aec874846cc7f20a083a 447 PIRSF PIRSF006485 1 444 2.3E-168 T 12-10-2018 IPR016484 GTP-binding protein EngA GO:0005525 VAPA_1c44160 8813de0b06cd76386208b09940d0ddeb 276 SUPERFAMILY SSF49482 27 199 2.22E-47 T 12-10-2018 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 VAPA_1c44160 8813de0b06cd76386208b09940d0ddeb 276 Pfam PF00775 Dioxygenase 47 181 1.4E-15 T 12-10-2018 IPR000627 Intradiol ring-cleavage dioxygenase, C-terminal GO:0003824|GO:0006725|GO:0008199|GO:0055114 VAPA_1c44160 8813de0b06cd76386208b09940d0ddeb 276 Gene3D G3DSA:2.60.130.10 16 196 5.2E-46 T 12-10-2018 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 VAPA_1c33420 8392d9faf0cfc51b414830ce4279e90d 103 Pfam PF13591 MerR HTH family regulatory protein 17 98 4.1E-12 T 12-10-2018 VAPA_1c33420 8392d9faf0cfc51b414830ce4279e90d 103 Gene3D G3DSA:1.10.1660.10 11 102 4.9E-21 T 12-10-2018 VAPA_2c00150 a5152f5c3ddba8aae44aa11ab514c132 479 Gene3D G3DSA:3.40.309.10 249 437 1.1E-153 T 12-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 VAPA_2c00150 a5152f5c3ddba8aae44aa11ab514c132 479 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 244 251 - T 12-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 VAPA_2c00150 a5152f5c3ddba8aae44aa11ab514c132 479 Pfam PF00171 Aldehyde dehydrogenase family 21 464 4.1E-145 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 VAPA_2c00150 a5152f5c3ddba8aae44aa11ab514c132 479 SUPERFAMILY SSF53720 3 466 1.57E-144 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 VAPA_2c00150 a5152f5c3ddba8aae44aa11ab514c132 479 Gene3D G3DSA:3.40.605.10 9 463 1.1E-153 T 12-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 VAPA_1c47380 8a4bb4a17c1e8b45d1ae3ad7a154e5b4 78 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 6 50 2.1E-7 T 12-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 VAPA_1c47380 8a4bb4a17c1e8b45d1ae3ad7a154e5b4 78 SUPERFAMILY SSF89447 1 48 2.79E-11 T 12-10-2018 IPR037914 SpoVT-AbrB domain superfamily VAPA_1c47380 8a4bb4a17c1e8b45d1ae3ad7a154e5b4 78 Gene3D G3DSA:2.10.260.10 1 78 2.2E-8 T 12-10-2018 VAPA_1c47380 8a4bb4a17c1e8b45d1ae3ad7a154e5b4 78 SMART SM00966 5 51 2.0E-6 T 12-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 VAPA_1c40780 edac5674736e0093969f32841bada832 352 SUPERFAMILY SSF51735 10 342 9.09E-60 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c40780 edac5674736e0093969f32841bada832 352 Gene3D G3DSA:3.40.50.720 1 344 3.6E-99 T 12-10-2018 VAPA_1c40780 edac5674736e0093969f32841bada832 352 Pfam PF01370 NAD dependent epimerase/dehydratase family 11 239 3.1E-23 T 12-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 VAPA_1c35490 374c1f11622fd3e04a7ead1b7b8ba5c3 407 Pfam PF04127 DNA / pantothenate metabolism flavoprotein 189 373 3.8E-63 T 12-10-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 VAPA_1c35490 374c1f11622fd3e04a7ead1b7b8ba5c3 407 Gene3D G3DSA:3.40.50.10300 188 405 2.4E-66 T 12-10-2018 IPR035929 CoaB-like superfamily KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 VAPA_1c35490 374c1f11622fd3e04a7ead1b7b8ba5c3 407 Pfam PF02441 Flavoprotein 7 181 2.1E-37 T 12-10-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 VAPA_1c35490 374c1f11622fd3e04a7ead1b7b8ba5c3 407 SUPERFAMILY SSF102645 187 403 3.53E-67 T 12-10-2018 IPR035929 CoaB-like superfamily KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 VAPA_1c35490 374c1f11622fd3e04a7ead1b7b8ba5c3 407 SUPERFAMILY SSF52507 1 183 1.57E-55 T 12-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 VAPA_1c35490 374c1f11622fd3e04a7ead1b7b8ba5c3 407 Gene3D G3DSA:3.40.50.1950 1 187 2.0E-51 T 12-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 VAPA_1c35490 374c1f11622fd3e04a7ead1b7b8ba5c3 407 TIGRFAM TIGR00521 coaBC_dfp: phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase 4 398 3.7E-120 T 12-10-2018 IPR005252 Coenzyme A biosynthesis bifunctional protein CoaBC GO:0004632|GO:0004633|GO:0010181|GO:0015937|GO:0015941 KEGG: 00770+4.1.1.36+6.3.2.5|MetaCyc: PWY-7851 VAPA_1c35700 a41659e1a85696ee820445d86179907e 518 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 283 503 1.2E-43 T 12-10-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 VAPA_1c35700 a41659e1a85696ee820445d86179907e 518 Gene3D G3DSA:2.60.40.3500 23 141 2.9E-27 T 12-10-2018 VAPA_1c35700 a41659e1a85696ee820445d86179907e 518 Gene3D G3DSA:3.40.630.40 270 516 3.4E-73 T 12-10-2018 VAPA_1c35700 a41659e1a85696ee820445d86179907e 518 SUPERFAMILY SSF53187 282 506 8.16E-49 T 12-10-2018 VAPA_1c35700 a41659e1a85696ee820445d86179907e 518 SMART SM00646 347 503 7.2E-52 T 12-10-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 VAPA_1c35700 a41659e1a85696ee820445d86179907e 518 Pfam PF11741 AMIN domain 35 138 7.1E-22 T 12-10-2018 IPR021731 AMIN domain VAPA_1c41610 98bc810da2c31ed080c18b560f5f827f 422 SUPERFAMILY SSF53822 29 410 8.24E-92 T 12-10-2018 IPR028082 Periplasmic binding protein-like I VAPA_1c41610 98bc810da2c31ed080c18b560f5f827f 422 Gene3D G3DSA:3.40.50.2300 32 375 4.2E-137 T 12-10-2018 VAPA_1c41610 98bc810da2c31ed080c18b560f5f827f 422 TIGRFAM TIGR03407 urea_ABC_UrtA: urea ABC transporter, urea binding protein 30 404 1.5E-180 T 12-10-2018 IPR017777 Urea ABC transporter, substrate-binding protein UrtA-like VAPA_1c41610 98bc810da2c31ed080c18b560f5f827f 422 Gene3D G3DSA:3.40.50.2300 145 394 4.2E-137 T 12-10-2018 VAPA_1c41610 98bc810da2c31ed080c18b560f5f827f 422 Pfam PF13433 Periplasmic binding protein domain 30 407 8.1E-174 T 12-10-2018 VAPA_1c54160 372c85f1355a2bbfcd6e6d154e9e9ad3 351 Pfam PF01261 Xylose isomerase-like TIM barrel 30 279 3.0E-36 T 12-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain VAPA_1c54160 372c85f1355a2bbfcd6e6d154e9e9ad3 351 Pfam PF07582 AP endonuclease family 2 C terminus 280 334 8.7E-21 T 12-10-2018 IPR011418 AP endonuclease, family 2, C-terminal VAPA_1c54160 372c85f1355a2bbfcd6e6d154e9e9ad3 351 Gene3D G3DSA:3.20.20.150 19 324 2.0E-68 T 12-10-2018 VAPA_1c54160 372c85f1355a2bbfcd6e6d154e9e9ad3 351 SUPERFAMILY SSF51658 8 323 2.76E-60 T 12-10-2018 IPR036237 Xylose isomerase-like superfamily VAPA_1c17380 5f606c6c302652311e5195d8555a20d6 471 Pfam PF03951 Glutamine synthetase, beta-Grasp domain 16 97 6.5E-30 T 12-10-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 VAPA_1c17380 5f606c6c302652311e5195d8555a20d6 471 SMART SM01230 104 381 2.1E-152 T 12-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 VAPA_1c17380 5f606c6c302652311e5195d8555a20d6 471 SUPERFAMILY SSF55931 104 470 6.57E-139 T 12-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 VAPA_1c17380 5f606c6c302652311e5195d8555a20d6 471 ProSitePatterns PS00180 Glutamine synthetase signature 1. 52 70 - T 12-10-2018 IPR027302 Glutamine synthetase, N-terminal conserved site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 VAPA_1c17380 5f606c6c302652311e5195d8555a20d6 471 Gene3D G3DSA:3.10.20.70 4 106 1.4E-38 T 12-10-2018 IPR036651 Glutamine synthetase, N-terminal domain superfamily GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 VAPA_1c17380 5f606c6c302652311e5195d8555a20d6 471 SUPERFAMILY SSF54368 4 102 1.96E-36 T 12-10-2018 IPR036651 Glutamine synthetase, N-terminal domain superfamily GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 VAPA_1c17380 5f606c6c302652311e5195d8555a20d6 471 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 261 276 - T 12-10-2018 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 VAPA_1c17380 5f606c6c302652311e5195d8555a20d6 471 TIGRFAM TIGR00653 GlnA: glutamine synthetase, type I 7 470 2.0E-201 T 12-10-2018 IPR004809 Glutamine synthetase type I GO:0004356|GO:0005737|GO:0009399 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 VAPA_1c17380 5f606c6c302652311e5195d8555a20d6 471 Gene3D G3DSA:3.30.590.10 107 459 2.8E-145 T 12-10-2018 VAPA_1c17380 5f606c6c302652311e5195d8555a20d6 471 Pfam PF00120 Glutamine synthetase, catalytic domain 104 468 1.9E-138 T 12-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 VAPA_1c16010 eef54b98163b04c46d7cee06a72130fa 253 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 147 175 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 VAPA_1c16010 eef54b98163b04c46d7cee06a72130fa 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 160 179 1.5E-12 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c16010 eef54b98163b04c46d7cee06a72130fa 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 86 97 1.5E-12 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c16010 eef54b98163b04c46d7cee06a72130fa 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 139 147 1.5E-12 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c16010 eef54b98163b04c46d7cee06a72130fa 253 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 11 196 0.007 T 12-10-2018 VAPA_1c16010 eef54b98163b04c46d7cee06a72130fa 253 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 17 249 1.2E-61 T 12-10-2018 VAPA_1c16010 eef54b98163b04c46d7cee06a72130fa 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 160 179 1.3E-42 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c16010 eef54b98163b04c46d7cee06a72130fa 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 12 29 1.3E-42 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c16010 eef54b98163b04c46d7cee06a72130fa 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 214 234 1.3E-42 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c16010 eef54b98163b04c46d7cee06a72130fa 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 86 97 1.3E-42 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c16010 eef54b98163b04c46d7cee06a72130fa 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 133 149 1.3E-42 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c16010 eef54b98163b04c46d7cee06a72130fa 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 181 198 1.3E-42 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c16010 eef54b98163b04c46d7cee06a72130fa 253 Gene3D G3DSA:3.40.50.720 1 252 2.3E-79 T 12-10-2018 VAPA_1c16010 eef54b98163b04c46d7cee06a72130fa 253 SUPERFAMILY SSF51735 10 252 3.31E-79 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_2c01280 586b2b2543c43e5972b382846d4252c9 263 Hamap MF_01974 Methionine aminopeptidase [map]. 5 253 39.679 T 12-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 VAPA_2c01280 586b2b2543c43e5972b382846d4252c9 263 Gene3D G3DSA:3.90.230.10 4 255 8.0E-104 T 12-10-2018 VAPA_2c01280 586b2b2543c43e5972b382846d4252c9 263 ProSitePatterns PS00680 Methionine aminopeptidase subfamily 1 signature. 170 188 - T 12-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 VAPA_2c01280 586b2b2543c43e5972b382846d4252c9 263 SUPERFAMILY SSF55920 7 254 1.22E-88 T 12-10-2018 IPR036005 Creatinase/aminopeptidase-like VAPA_2c01280 586b2b2543c43e5972b382846d4252c9 263 PRINTS PR00599 Methionine aminopeptidase-1 signature 195 207 2.6E-22 T 12-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 VAPA_2c01280 586b2b2543c43e5972b382846d4252c9 263 PRINTS PR00599 Methionine aminopeptidase-1 signature 71 84 2.6E-22 T 12-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 VAPA_2c01280 586b2b2543c43e5972b382846d4252c9 263 PRINTS PR00599 Methionine aminopeptidase-1 signature 164 176 2.6E-22 T 12-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 VAPA_2c01280 586b2b2543c43e5972b382846d4252c9 263 PRINTS PR00599 Methionine aminopeptidase-1 signature 94 110 2.6E-22 T 12-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 VAPA_2c01280 586b2b2543c43e5972b382846d4252c9 263 Pfam PF00557 Metallopeptidase family M24 15 244 2.5E-51 T 12-10-2018 IPR000994 Peptidase M24 VAPA_2c01280 586b2b2543c43e5972b382846d4252c9 263 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 5 252 6.4E-94 T 12-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 VAPA_1c35880 e794f126da483a7819857490756a0c41 358 SUPERFAMILY SSF159245 27 352 7.72E-108 T 12-10-2018 VAPA_1c35880 e794f126da483a7819857490756a0c41 358 Gene3D G3DSA:2.40.370.10 223 358 9.0E-46 T 12-10-2018 IPR023374 AttH-like domain superfamily VAPA_1c35880 e794f126da483a7819857490756a0c41 358 Gene3D G3DSA:2.40.370.10 36 222 1.1E-71 T 12-10-2018 IPR023374 AttH-like domain superfamily VAPA_1c35880 e794f126da483a7819857490756a0c41 358 Pfam PF17186 Lipocalin-like domain 223 352 5.3E-40 T 12-10-2018 VAPA_1c35880 e794f126da483a7819857490756a0c41 358 Pfam PF07143 CrtC N-terminal lipocalin domain 48 219 1.7E-57 T 12-10-2018 IPR010791 AttH domain VAPA_1c24220 9b64b388fa19c7ddf2642c8fe01347aa 257 Gene3D G3DSA:3.40.225.10 8 257 2.6E-77 T 12-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily VAPA_1c24220 9b64b388fa19c7ddf2642c8fe01347aa 257 SUPERFAMILY SSF53639 12 224 1.53E-58 T 12-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily VAPA_1c24220 9b64b388fa19c7ddf2642c8fe01347aa 257 SMART SM01007 19 199 1.7E-63 T 12-10-2018 IPR001303 Class II aldolase/adducin N-terminal VAPA_1c24220 9b64b388fa19c7ddf2642c8fe01347aa 257 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 20 199 2.3E-48 T 12-10-2018 IPR001303 Class II aldolase/adducin N-terminal VAPA_1c24510 c012e72cc69e37e0e0d8e0c4c55002ae 345 Pfam PF12849 PBP superfamily domain 26 305 1.5E-62 T 12-10-2018 IPR024370 PBP domain VAPA_1c24510 c012e72cc69e37e0e0d8e0c4c55002ae 345 Gene3D G3DSA:3.40.190.10 101 276 1.7E-125 T 12-10-2018 VAPA_1c24510 c012e72cc69e37e0e0d8e0c4c55002ae 345 PIRSF PIRSF002756 3 337 9.4E-110 T 12-10-2018 IPR005673 Phosphate ABC transporter, substrate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 VAPA_1c24510 c012e72cc69e37e0e0d8e0c4c55002ae 345 Gene3D G3DSA:3.40.190.10 27 323 1.7E-125 T 12-10-2018 VAPA_1c24510 c012e72cc69e37e0e0d8e0c4c55002ae 345 TIGRFAM TIGR00975 3a0107s03: phosphate ABC transporter, phosphate-binding protein PstS 27 334 4.9E-127 T 12-10-2018 IPR005673 Phosphate ABC transporter, substrate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 VAPA_1c24510 c012e72cc69e37e0e0d8e0c4c55002ae 345 SUPERFAMILY SSF53850 27 335 5.44E-99 T 12-10-2018 VAPA_1c15410 438df0d8d43703927096ff9206b4269c 428 TIGRFAM TIGR01814 kynureninase: kynureninase 7 412 2.4E-94 T 12-10-2018 IPR010111 Kynureninase GO:0005737|GO:0006569|GO:0009435|GO:0030170|GO:0030429 KEGG: 00380+3.7.1.3|MetaCyc: PWY-5651|MetaCyc: PWY-6309|Reactome: R-HSA-71240 VAPA_1c15410 438df0d8d43703927096ff9206b4269c 428 PIRSF PIRSF038800 1 419 3.6E-140 T 12-10-2018 IPR010111 Kynureninase GO:0005737|GO:0006569|GO:0009435|GO:0030170|GO:0030429 KEGG: 00380+3.7.1.3|MetaCyc: PWY-5651|MetaCyc: PWY-6309|Reactome: R-HSA-71240 VAPA_1c15410 438df0d8d43703927096ff9206b4269c 428 Pfam PF00266 Aminotransferase class-V 78 296 8.5E-17 T 12-10-2018 IPR000192 Aminotransferase class V domain VAPA_1c15410 438df0d8d43703927096ff9206b4269c 428 Gene3D G3DSA:3.90.1150.10 10 411 6.8E-152 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 VAPA_1c15410 438df0d8d43703927096ff9206b4269c 428 Gene3D G3DSA:3.40.640.10 41 309 6.8E-152 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 VAPA_1c15410 438df0d8d43703927096ff9206b4269c 428 Hamap MF_01970 Kynureninase [kynU]. 1 411 34.142 T 12-10-2018 IPR010111 Kynureninase GO:0005737|GO:0006569|GO:0009435|GO:0030170|GO:0030429 KEGG: 00380+3.7.1.3|MetaCyc: PWY-5651|MetaCyc: PWY-6309|Reactome: R-HSA-71240 VAPA_1c15410 438df0d8d43703927096ff9206b4269c 428 SUPERFAMILY SSF53383 3 412 3.1E-84 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase VAPA_2c01120 2638f0cd0a75e6436bf87ad961d62395 144 Gene3D G3DSA:3.10.129.10 18 143 1.1E-37 T 12-10-2018 VAPA_2c01120 2638f0cd0a75e6436bf87ad961d62395 144 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 26 137 2.4E-17 T 12-10-2018 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-77289 VAPA_2c01120 2638f0cd0a75e6436bf87ad961d62395 144 SUPERFAMILY SSF54637 15 140 4.98E-30 T 12-10-2018 IPR029069 HotDog domain superfamily VAPA_2c01120 2638f0cd0a75e6436bf87ad961d62395 144 Pfam PF03061 Thioesterase superfamily 60 131 3.0E-10 T 12-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 VAPA_1c34960 49f5463a7c3a84de3056fcef053f2115 153 Gene3D G3DSA:2.30.30.40 32 88 5.8E-9 T 12-10-2018 VAPA_1c34960 49f5463a7c3a84de3056fcef053f2115 153 Gene3D G3DSA:2.30.30.40 89 149 3.3E-14 T 12-10-2018 VAPA_1c34960 49f5463a7c3a84de3056fcef053f2115 153 SMART SM00287 28 91 0.5 T 12-10-2018 IPR003646 SH3-like domain, bacterial-type VAPA_1c34960 49f5463a7c3a84de3056fcef053f2115 153 SMART SM00287 95 153 0.33 T 12-10-2018 IPR003646 SH3-like domain, bacterial-type VAPA_1c34960 49f5463a7c3a84de3056fcef053f2115 153 Pfam PF06347 Bacterial SH3 domain 98 152 4.5E-12 T 12-10-2018 IPR010466 Protein of unknown function DUF1058 VAPA_1c34960 49f5463a7c3a84de3056fcef053f2115 153 Pfam PF06347 Bacterial SH3 domain 37 87 2.0E-10 T 12-10-2018 IPR010466 Protein of unknown function DUF1058 VAPA_1c05430 6a56cf9fd123186de377e0fa563b4e60 215 Pfam PF01323 DSBA-like thioredoxin domain 54 189 3.5E-17 T 12-10-2018 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590|Reactome: R-HSA-9033241 VAPA_1c05430 6a56cf9fd123186de377e0fa563b4e60 215 SUPERFAMILY SSF52833 30 192 3.71E-37 T 12-10-2018 IPR036249 Thioredoxin-like superfamily VAPA_1c05430 6a56cf9fd123186de377e0fa563b4e60 215 Gene3D G3DSA:3.40.30.10 18 214 1.0E-51 T 12-10-2018 VAPA_1c05430 6a56cf9fd123186de377e0fa563b4e60 215 ProSitePatterns PS00194 Thioredoxin family active site. 54 72 - T 12-10-2018 IPR017937 Thioredoxin, conserved site GO:0045454 VAPA_1c05430 6a56cf9fd123186de377e0fa563b4e60 215 PIRSF PIRSF001488 3 214 3.8E-45 T 12-10-2018 IPR023205 Thiol:disulphide interchange protein DsbA/DsbL VAPA_1c05220 2ed161dd14a69420f2085ab57f642c26 268 SUPERFAMILY SSF52096 5 268 1.36E-77 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily VAPA_1c05220 2ed161dd14a69420f2085ab57f642c26 268 Pfam PF00378 Enoyl-CoA hydratase/isomerase 13 266 9.6E-63 T 12-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 VAPA_1c05220 2ed161dd14a69420f2085ab57f642c26 268 Gene3D G3DSA:3.90.226.10 2 209 8.3E-64 T 12-10-2018 VAPA_1c05220 2ed161dd14a69420f2085ab57f642c26 268 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 108 128 - T 12-10-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824 VAPA_1c05220 2ed161dd14a69420f2085ab57f642c26 268 Gene3D G3DSA:1.10.12.10 211 268 3.3E-14 T 12-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal VAPA_2c09550 46fcf797766a4d630bb688dd68c96e7b 3357 Gene3D G3DSA:2.160.20.10 71 373 2.2E-99 T 12-10-2018 IPR012334 Pectin lyase fold VAPA_2c09550 46fcf797766a4d630bb688dd68c96e7b 3357 TIGRFAM TIGR01901 adhes_NPXG: filamentous hemagglutinin family N-terminal domain 103 199 6.5E-21 T 12-10-2018 IPR008638 Filamentous haemagglutinin, N-terminal VAPA_2c09550 46fcf797766a4d630bb688dd68c96e7b 3357 Pfam PF13332 Haemagluttinin repeat 2590 2762 2.9E-43 T 12-10-2018 IPR025157 Hemagglutinin repeat VAPA_2c09550 46fcf797766a4d630bb688dd68c96e7b 3357 Pfam PF13332 Haemagluttinin repeat 2361 2511 7.8E-9 T 12-10-2018 IPR025157 Hemagglutinin repeat VAPA_2c09550 46fcf797766a4d630bb688dd68c96e7b 3357 Pfam PF13332 Haemagluttinin repeat 2283 2340 0.0046 T 12-10-2018 IPR025157 Hemagglutinin repeat VAPA_2c09550 46fcf797766a4d630bb688dd68c96e7b 3357 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 1366 1388 0.61 T 12-10-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat VAPA_2c09550 46fcf797766a4d630bb688dd68c96e7b 3357 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 1785 1822 0.98 T 12-10-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat VAPA_2c09550 46fcf797766a4d630bb688dd68c96e7b 3357 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 1197 1237 0.015 T 12-10-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat VAPA_2c09550 46fcf797766a4d630bb688dd68c96e7b 3357 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 2152 2185 0.59 T 12-10-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat VAPA_2c09550 46fcf797766a4d630bb688dd68c96e7b 3357 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 1521 1550 0.053 T 12-10-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat VAPA_2c09550 46fcf797766a4d630bb688dd68c96e7b 3357 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 2110 2147 0.36 T 12-10-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat VAPA_2c09550 46fcf797766a4d630bb688dd68c96e7b 3357 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 934 973 1.3 T 12-10-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat VAPA_2c09550 46fcf797766a4d630bb688dd68c96e7b 3357 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 499 529 0.89 T 12-10-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat VAPA_2c09550 46fcf797766a4d630bb688dd68c96e7b 3357 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 1325 1358 1.0E-6 T 12-10-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat VAPA_2c09550 46fcf797766a4d630bb688dd68c96e7b 3357 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 487 518 2.2 T 12-10-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat VAPA_2c09550 46fcf797766a4d630bb688dd68c96e7b 3357 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 974 1014 0.0032 T 12-10-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat VAPA_2c09550 46fcf797766a4d630bb688dd68c96e7b 3357 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 620 660 2.1E-4 T 12-10-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat VAPA_2c09550 46fcf797766a4d630bb688dd68c96e7b 3357 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 578 618 0.0022 T 12-10-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat VAPA_2c09550 46fcf797766a4d630bb688dd68c96e7b 3357 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 958 993 2.3E-5 T 12-10-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat VAPA_2c09550 46fcf797766a4d630bb688dd68c96e7b 3357 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 1265 1300 7.0E-6 T 12-10-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat VAPA_2c09550 46fcf797766a4d630bb688dd68c96e7b 3357 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 1433 1473 0.064 T 12-10-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat VAPA_2c09550 46fcf797766a4d630bb688dd68c96e7b 3357 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 387 421 2.3 T 12-10-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat VAPA_2c09550 46fcf797766a4d630bb688dd68c96e7b 3357 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 1018 1056 0.0051 T 12-10-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat VAPA_2c09550 46fcf797766a4d630bb688dd68c96e7b 3357 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 1143 1182 0.0046 T 12-10-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat VAPA_2c09550 46fcf797766a4d630bb688dd68c96e7b 3357 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 1059 1100 0.0046 T 12-10-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat VAPA_2c09550 46fcf797766a4d630bb688dd68c96e7b 3357 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 337 375 0.5 T 12-10-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat VAPA_2c09550 46fcf797766a4d630bb688dd68c96e7b 3357 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 1566 1591 0.64 T 12-10-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat VAPA_2c09550 46fcf797766a4d630bb688dd68c96e7b 3357 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 848 885 0.22 T 12-10-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat VAPA_2c09550 46fcf797766a4d630bb688dd68c96e7b 3357 Pfam PF05860 haemagglutination activity domain 71 202 3.2E-31 T 12-10-2018 IPR008638 Filamentous haemagglutinin, N-terminal VAPA_2c09550 46fcf797766a4d630bb688dd68c96e7b 3357 Pfam PF05594 Haemagluttinin repeat 252 337 1.7E-5 T 12-10-2018 IPR008619 Filamentous haemagglutinin repeat VAPA_2c09550 46fcf797766a4d630bb688dd68c96e7b 3357 Pfam PF05594 Haemagluttinin repeat 1564 1596 86.0 T 12-10-2018 IPR008619 Filamentous haemagglutinin repeat VAPA_2c09550 46fcf797766a4d630bb688dd68c96e7b 3357 Pfam PF05594 Haemagluttinin repeat 733 787 23.0 T 12-10-2018 IPR008619 Filamentous haemagglutinin repeat VAPA_2c09550 46fcf797766a4d630bb688dd68c96e7b 3357 Pfam PF05594 Haemagluttinin repeat 532 575 0.0072 T 12-10-2018 IPR008619 Filamentous haemagglutinin repeat VAPA_2c09550 46fcf797766a4d630bb688dd68c96e7b 3357 Pfam PF05594 Haemagluttinin repeat 1747 1824 2.8 T 12-10-2018 IPR008619 Filamentous haemagglutinin repeat VAPA_2c09550 46fcf797766a4d630bb688dd68c96e7b 3357 Pfam PF05594 Haemagluttinin repeat 604 674 0.76 T 12-10-2018 IPR008619 Filamentous haemagglutinin repeat VAPA_2c09550 46fcf797766a4d630bb688dd68c96e7b 3357 Pfam PF05594 Haemagluttinin repeat 487 523 1.5 T 12-10-2018 IPR008619 Filamentous haemagglutinin repeat VAPA_2c09550 46fcf797766a4d630bb688dd68c96e7b 3357 Pfam PF05594 Haemagluttinin repeat 1196 1236 110.0 T 12-10-2018 IPR008619 Filamentous haemagglutinin repeat VAPA_2c09550 46fcf797766a4d630bb688dd68c96e7b 3357 Pfam PF05594 Haemagluttinin repeat 2103 2147 6.9 T 12-10-2018 IPR008619 Filamentous haemagglutinin repeat VAPA_2c09550 46fcf797766a4d630bb688dd68c96e7b 3357 Pfam PF05594 Haemagluttinin repeat 1410 1487 0.0059 T 12-10-2018 IPR008619 Filamentous haemagglutinin repeat VAPA_2c09550 46fcf797766a4d630bb688dd68c96e7b 3357 Pfam PF05594 Haemagluttinin repeat 1312 1354 0.074 T 12-10-2018 IPR008619 Filamentous haemagglutinin repeat VAPA_2c09550 46fcf797766a4d630bb688dd68c96e7b 3357 Pfam PF05594 Haemagluttinin repeat 949 1015 1.2 T 12-10-2018 IPR008619 Filamentous haemagglutinin repeat VAPA_2c09550 46fcf797766a4d630bb688dd68c96e7b 3357 Pfam PF05594 Haemagluttinin repeat 2155 2196 51.0 T 12-10-2018 IPR008619 Filamentous haemagglutinin repeat VAPA_2c09550 46fcf797766a4d630bb688dd68c96e7b 3357 Pfam PF05594 Haemagluttinin repeat 1042 1085 20.0 T 12-10-2018 IPR008619 Filamentous haemagglutinin repeat VAPA_2c09550 46fcf797766a4d630bb688dd68c96e7b 3357 SMART SM00912 84 204 8.1E-42 T 12-10-2018 IPR008638 Filamentous haemagglutinin, N-terminal VAPA_2c09550 46fcf797766a4d630bb688dd68c96e7b 3357 SUPERFAMILY SSF51126 73 370 2.23E-62 T 12-10-2018 IPR011050 Pectin lyase fold/virulence factor VAPA_1c13740 ea9c226b9456bd4798df5d91e5d328bf 260 Hamap MF_00652 UPF0246 protein YaaA [yaaA]. 1 259 32.168 T 12-10-2018 IPR005583 Peroxide stress protein YaaA VAPA_1c13740 ea9c226b9456bd4798df5d91e5d328bf 260 Pfam PF03883 Peroxide stress protein YaaA 1 246 4.9E-82 T 12-10-2018 IPR005583 Peroxide stress protein YaaA VAPA_1c53350 3c32467c519723dd95cf246639eacfb3 422 SUPERFAMILY SSF142764 6 421 2.09E-124 T 12-10-2018 VAPA_1c53350 3c32467c519723dd95cf246639eacfb3 422 Gene3D G3DSA:3.40.50.10840 3 239 2.7E-84 T 12-10-2018 IPR037051 Four-carbon acid sugar kinase, N-terminal domain superfamily VAPA_1c53350 3c32467c519723dd95cf246639eacfb3 422 Gene3D G3DSA:3.40.980.20 240 422 2.4E-55 T 12-10-2018 VAPA_1c53350 3c32467c519723dd95cf246639eacfb3 422 Pfam PF17042 Putative nucleotide-binding of sugar-metabolising enzyme 254 414 2.3E-40 T 12-10-2018 IPR031475 Four-carbon acid sugar kinase, C-terminal domain VAPA_1c53350 3c32467c519723dd95cf246639eacfb3 422 Pfam PF07005 Putative sugar-binding N-terminal domain 6 229 1.8E-70 T 12-10-2018 IPR010737 Four-carbon acid sugar kinase, N-terminal domain VAPA_1c14420 2c387b1f5a06938d5f7a5eea1c2829ec 173 SMART SM00506 4 133 1.9E-47 T 12-10-2018 IPR002589 Macro domain VAPA_1c14420 2c387b1f5a06938d5f7a5eea1c2829ec 173 SUPERFAMILY SSF52949 6 168 2.35E-61 T 12-10-2018 VAPA_1c14420 2c387b1f5a06938d5f7a5eea1c2829ec 173 Pfam PF01661 Macro domain 21 133 2.4E-42 T 12-10-2018 IPR002589 Macro domain VAPA_1c14420 2c387b1f5a06938d5f7a5eea1c2829ec 173 Gene3D G3DSA:3.40.220.10 1 172 2.2E-72 T 12-10-2018 VAPA_1c52280 8b725ec27c6679b8eefea6d47a13cc8f 422 Gene3D G3DSA:3.40.50.150 117 401 9.4E-98 T 12-10-2018 VAPA_1c52280 8b725ec27c6679b8eefea6d47a13cc8f 422 PIRSF PIRSF003085 5 414 2.0E-128 T 12-10-2018 IPR003333 Mycolic acid cyclopropane synthase GO:0008610 VAPA_1c52280 8b725ec27c6679b8eefea6d47a13cc8f 422 SUPERFAMILY SSF53335 120 397 6.44E-73 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase VAPA_1c52280 8b725ec27c6679b8eefea6d47a13cc8f 422 Pfam PF02353 Mycolic acid cyclopropane synthetase 109 392 1.6E-94 T 12-10-2018 VAPA_1c30550 ea8eff7bedf3d25f6be988a2ab11d419 101 SUPERFAMILY SSF54909 1 99 7.75E-23 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel VAPA_1c30550 ea8eff7bedf3d25f6be988a2ab11d419 101 Pfam PF07978 NIPSNAP 6 99 1.4E-25 T 12-10-2018 IPR012577 NIPSNAP VAPA_1c30550 ea8eff7bedf3d25f6be988a2ab11d419 101 Gene3D G3DSA:3.30.70.100 6 95 2.1E-6 T 12-10-2018 VAPA_1c33550 17943adf9ccaca73df450124ee4eb081 503 Pfam PF06114 IrrE N-terminal-like domain 205 314 1.4E-20 T 12-10-2018 IPR010359 IrrE N-terminal-like domain VAPA_1c33550 17943adf9ccaca73df450124ee4eb081 503 SMART SM00530 9 64 6.2E-15 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 VAPA_1c33550 17943adf9ccaca73df450124ee4eb081 503 SUPERFAMILY SSF47413 3 68 4.56E-15 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 VAPA_1c33550 17943adf9ccaca73df450124ee4eb081 503 PIRSF PIRSF019251 1 476 2.2E-196 T 12-10-2018 IPR026281 HTH-type transcriptional regulator RamB GO:0006355 VAPA_1c33550 17943adf9ccaca73df450124ee4eb081 503 Gene3D G3DSA:1.10.260.40 3 82 1.5E-14 T 12-10-2018 VAPA_1c33550 17943adf9ccaca73df450124ee4eb081 503 Pfam PF01381 Helix-turn-helix 10 62 1.1E-12 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 VAPA_1c33550 17943adf9ccaca73df450124ee4eb081 503 Pfam PF09856 Predicted transcriptional regulator (DUF2083) 316 471 1.6E-70 T 12-10-2018 IPR018653 Domain of unknown function DUF2083,transcriptional regulator VAPA_2c02820 6bffd955e73d1b6501beacdb11b0ce76 579 SUPERFAMILY SSF56425 232 352 2.09E-31 T 12-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 VAPA_2c02820 6bffd955e73d1b6501beacdb11b0ce76 579 SUPERFAMILY SSF51905 4 431 7.99E-56 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_2c02820 6bffd955e73d1b6501beacdb11b0ce76 579 PIRSF PIRSF000171 1 563 8.4E-38 T 12-10-2018 VAPA_2c02820 6bffd955e73d1b6501beacdb11b0ce76 579 Gene3D G3DSA:3.90.700.10 242 358 4.2E-121 T 12-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 VAPA_2c02820 6bffd955e73d1b6501beacdb11b0ce76 579 Pfam PF02910 Fumarate reductase flavoprotein C-term 445 565 5.7E-24 T 12-10-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 VAPA_2c02820 6bffd955e73d1b6501beacdb11b0ce76 579 Gene3D G3DSA:1.20.58.100 428 532 3.1E-26 T 12-10-2018 VAPA_2c02820 6bffd955e73d1b6501beacdb11b0ce76 579 Gene3D G3DSA:3.50.50.60 9 403 4.2E-121 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_2c02820 6bffd955e73d1b6501beacdb11b0ce76 579 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 355 377 2.6E-6 T 12-10-2018 VAPA_2c02820 6bffd955e73d1b6501beacdb11b0ce76 579 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 10 29 2.6E-6 T 12-10-2018 VAPA_2c02820 6bffd955e73d1b6501beacdb11b0ce76 579 Pfam PF00890 FAD binding domain 9 391 2.5E-69 T 12-10-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 VAPA_2c02820 6bffd955e73d1b6501beacdb11b0ce76 579 SUPERFAMILY SSF46977 441 567 1.44E-32 T 12-10-2018 IPR037099 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain superfamily GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 VAPA_1c54730 500c992e32dbd89f4b1112e9633d4f2e 324 Gene3D G3DSA:3.40.190.10 94 293 1.1E-58 T 12-10-2018 VAPA_1c54730 500c992e32dbd89f4b1112e9633d4f2e 324 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 9 65 1.8E-18 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c54730 500c992e32dbd89f4b1112e9633d4f2e 324 Gene3D G3DSA:3.40.190.10 166 268 1.1E-58 T 12-10-2018 VAPA_1c54730 500c992e32dbd89f4b1112e9633d4f2e 324 Gene3D G3DSA:1.10.10.10 6 92 4.6E-24 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c54730 500c992e32dbd89f4b1112e9633d4f2e 324 SUPERFAMILY SSF53850 91 301 3.08E-42 T 12-10-2018 VAPA_1c54730 500c992e32dbd89f4b1112e9633d4f2e 324 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 21 32 5.5E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c54730 500c992e32dbd89f4b1112e9633d4f2e 324 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 32 42 5.5E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c54730 500c992e32dbd89f4b1112e9633d4f2e 324 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 53 5.5E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c54730 500c992e32dbd89f4b1112e9633d4f2e 324 SUPERFAMILY SSF46785 8 90 4.95E-20 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c54730 500c992e32dbd89f4b1112e9633d4f2e 324 Pfam PF03466 LysR substrate binding domain 90 295 7.8E-39 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_1c01170 5616cc4ef2e4c7b5530cf43d12621d26 462 Gene3D G3DSA:3.90.1300.10 1 461 1.6E-131 T 12-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 VAPA_1c01170 5616cc4ef2e4c7b5530cf43d12621d26 462 SUPERFAMILY SSF75304 4 460 1.15E-122 T 12-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 VAPA_1c01170 5616cc4ef2e4c7b5530cf43d12621d26 462 Pfam PF01425 Amidase 26 444 6.1E-98 T 12-10-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 VAPA_1c14880 7c3802107ccf27059b72002109d06f80 224 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 68 99 - T 12-10-2018 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 VAPA_1c14880 7c3802107ccf27059b72002109d06f80 224 Pfam PF04542 Sigma-70 region 2 47 108 1.9E-15 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 VAPA_1c14880 7c3802107ccf27059b72002109d06f80 224 TIGRFAM TIGR02939 RpoE_Sigma70: RNA polymerase sigma factor RpoE 25 216 2.3E-78 T 12-10-2018 IPR014286 RNA polymerase sigma-70 RpoE type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 VAPA_1c14880 7c3802107ccf27059b72002109d06f80 224 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 42 209 2.1E-29 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 VAPA_1c14880 7c3802107ccf27059b72002109d06f80 224 SUPERFAMILY SSF88946 27 127 1.54E-29 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 VAPA_1c14880 7c3802107ccf27059b72002109d06f80 224 Pfam PF08281 Sigma-70, region 4 156 207 9.7E-20 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 VAPA_1c14880 7c3802107ccf27059b72002109d06f80 224 Gene3D G3DSA:1.10.1740.10 26 138 7.9E-34 T 12-10-2018 VAPA_1c14880 7c3802107ccf27059b72002109d06f80 224 SUPERFAMILY SSF88659 150 211 1.7E-18 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like VAPA_1c14880 7c3802107ccf27059b72002109d06f80 224 Gene3D G3DSA:1.10.10.10 149 217 1.2E-23 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c52430 40cf26c9ae855044016fc7f31d116c9e 143 SUPERFAMILY SSF52080 4 142 6.15E-42 T 12-10-2018 IPR036227 Ribosomal L18e/L15P superfamily VAPA_1c52430 40cf26c9ae855044016fc7f31d116c9e 143 Hamap MF_01341 50S ribosomal protein L15 [rplO]. 3 143 18.924 T 12-10-2018 IPR030878 Ribosomal protein L15 GO:0003735|GO:0006412|GO:0015934 VAPA_1c52430 40cf26c9ae855044016fc7f31d116c9e 143 TIGRFAM TIGR01071 rplO_bact: ribosomal protein uL15 2 142 1.4E-43 T 12-10-2018 IPR005749 Ribosomal protein L15, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 VAPA_1c52430 40cf26c9ae855044016fc7f31d116c9e 143 Pfam PF00828 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A 28 142 5.5E-28 T 12-10-2018 IPR021131 Ribosomal protein L18e/L15P VAPA_1c52430 40cf26c9ae855044016fc7f31d116c9e 143 Gene3D G3DSA:3.100.10.10 72 143 1.2E-10 T 12-10-2018 VAPA_1c04350 759e5d002b3e5bc38a5e7a1352b4a135 571 Gene3D G3DSA:3.90.700.10 350 497 1.7E-140 T 12-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 VAPA_1c04350 759e5d002b3e5bc38a5e7a1352b4a135 571 Gene3D G3DSA:3.50.50.60 9 560 1.7E-140 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c04350 759e5d002b3e5bc38a5e7a1352b4a135 571 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 524 539 1.0E-6 T 12-10-2018 VAPA_1c04350 759e5d002b3e5bc38a5e7a1352b4a135 571 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 11 33 1.0E-6 T 12-10-2018 VAPA_1c04350 759e5d002b3e5bc38a5e7a1352b4a135 571 Pfam PF00890 FAD binding domain 11 549 2.1E-89 T 12-10-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 VAPA_1c04350 759e5d002b3e5bc38a5e7a1352b4a135 571 SUPERFAMILY SSF51905 3 565 3.59E-42 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c04350 759e5d002b3e5bc38a5e7a1352b4a135 571 SUPERFAMILY SSF56425 342 508 1.92E-34 T 12-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 VAPA_1c25090 161e4d760ad7f1d5590dabbd6744cb33 90 Pfam PF14110 Domain of unknown function (DUF4282) 5 78 5.4E-11 T 12-10-2018 IPR025557 Protein of unknown function DUF4282 VAPA_1c34210 868a7b1739d76c7f5caf657632cc17bb 469 SUPERFAMILY SSF103473 14 430 5.49E-55 T 12-10-2018 IPR036259 MFS transporter superfamily VAPA_1c34210 868a7b1739d76c7f5caf657632cc17bb 469 Gene3D G3DSA:1.20.1250.20 16 440 2.6E-58 T 12-10-2018 VAPA_1c34210 868a7b1739d76c7f5caf657632cc17bb 469 Pfam PF07690 Major Facilitator Superfamily 26 389 3.9E-24 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 VAPA_1c34210 868a7b1739d76c7f5caf657632cc17bb 469 ProSitePatterns PS00216 Sugar transport proteins signature 1. 301 318 - T 12-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 VAPA_1c51500 44afdbf6a199c9a72c0e37bfafcb6c63 220 Pfam PF13417 Glutathione S-transferase, N-terminal domain 14 89 8.6E-18 T 12-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 VAPA_1c51500 44afdbf6a199c9a72c0e37bfafcb6c63 220 Pfam PF00043 Glutathione S-transferase, C-terminal domain 132 202 1.9E-8 T 12-10-2018 IPR004046 Glutathione S-transferase, C-terminal VAPA_1c51500 44afdbf6a199c9a72c0e37bfafcb6c63 220 SUPERFAMILY SSF52833 8 96 3.94E-26 T 12-10-2018 IPR036249 Thioredoxin-like superfamily VAPA_1c51500 44afdbf6a199c9a72c0e37bfafcb6c63 220 Gene3D G3DSA:1.20.1050.10 96 205 1.5E-25 T 12-10-2018 VAPA_1c51500 44afdbf6a199c9a72c0e37bfafcb6c63 220 SUPERFAMILY SSF47616 82 208 3.76E-24 T 12-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily VAPA_1c51500 44afdbf6a199c9a72c0e37bfafcb6c63 220 Gene3D G3DSA:3.40.30.10 9 92 6.1E-27 T 12-10-2018 VAPA_1c13400 a0cd37d4aad6f3bd5fd791598d56eb4a 371 SUPERFAMILY SSF47203 215 362 1.77E-32 T 12-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 VAPA_1c13400 a0cd37d4aad6f3bd5fd791598d56eb4a 371 SUPERFAMILY SSF56645 1 207 4.32E-41 T 12-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 VAPA_1c13400 a0cd37d4aad6f3bd5fd791598d56eb4a 371 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 115 9.4E-20 T 12-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 VAPA_1c13400 a0cd37d4aad6f3bd5fd791598d56eb4a 371 Gene3D G3DSA:1.10.540.10 1 117 3.5E-28 T 12-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 VAPA_1c13400 a0cd37d4aad6f3bd5fd791598d56eb4a 371 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 215 362 1.2E-21 T 12-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 VAPA_1c13400 a0cd37d4aad6f3bd5fd791598d56eb4a 371 Gene3D G3DSA:1.20.140.10 228 367 9.1E-29 T 12-10-2018 VAPA_1c13400 a0cd37d4aad6f3bd5fd791598d56eb4a 371 Gene3D G3DSA:2.40.110.10 118 222 7.3E-17 T 12-10-2018 VAPA_1c09100 2a87395f7ad448884eb4c18eaab78258 370 SUPERFAMILY SSF55469 48 125 2.62E-8 T 12-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 VAPA_1c09100 2a87395f7ad448884eb4c18eaab78258 370 Pfam PF00881 Nitroreductase family 157 352 1.6E-5 T 12-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 VAPA_1c09100 2a87395f7ad448884eb4c18eaab78258 370 Gene3D G3DSA:3.40.109.10 148 370 4.4E-53 T 12-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 VAPA_1c09100 2a87395f7ad448884eb4c18eaab78258 370 Gene3D G3DSA:3.40.109.10 52 146 3.9E-21 T 12-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 VAPA_1c09100 2a87395f7ad448884eb4c18eaab78258 370 SUPERFAMILY SSF55469 154 346 6.04E-12 T 12-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 VAPA_2c11490 d02760bea6d7840c717a322bf31b83c7 365 SUPERFAMILY SSF55874 210 358 5.37E-31 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_2c11490 d02760bea6d7840c717a322bf31b83c7 365 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 249 358 1.0E-15 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase VAPA_2c11490 d02760bea6d7840c717a322bf31b83c7 365 PRINTS PR00344 Bacterial sensor protein C-terminal signature 290 304 1.5E-10 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_2c11490 d02760bea6d7840c717a322bf31b83c7 365 PRINTS PR00344 Bacterial sensor protein C-terminal signature 319 337 1.5E-10 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_2c11490 d02760bea6d7840c717a322bf31b83c7 365 PRINTS PR00344 Bacterial sensor protein C-terminal signature 308 318 1.5E-10 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_2c11490 d02760bea6d7840c717a322bf31b83c7 365 PRINTS PR00344 Bacterial sensor protein C-terminal signature 344 357 1.5E-10 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_2c11490 d02760bea6d7840c717a322bf31b83c7 365 SMART SM00387 248 360 5.6E-24 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase VAPA_2c11490 d02760bea6d7840c717a322bf31b83c7 365 Gene3D G3DSA:3.30.565.10 208 363 9.1E-32 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_1c46140 16157845d3933638bcebfbfd697535be 226 Gene3D G3DSA:1.10.10.10 104 226 1.6E-31 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c46140 16157845d3933638bcebfbfd697535be 226 ProSitePatterns PS00622 LuxR-type HTH domain signature. 179 206 - T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_1c46140 16157845d3933638bcebfbfd697535be 226 SUPERFAMILY SSF52172 6 175 1.42E-17 T 12-10-2018 IPR011006 CheY-like superfamily VAPA_1c46140 16157845d3933638bcebfbfd697535be 226 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 165 179 2.8E-13 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_1c46140 16157845d3933638bcebfbfd697535be 226 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 179 195 2.8E-13 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_1c46140 16157845d3933638bcebfbfd697535be 226 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 195 207 2.8E-13 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_1c46140 16157845d3933638bcebfbfd697535be 226 SMART SM00421 162 219 2.0E-24 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_1c46140 16157845d3933638bcebfbfd697535be 226 Pfam PF00196 Bacterial regulatory proteins, luxR family 165 218 1.9E-20 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_1c46140 16157845d3933638bcebfbfd697535be 226 Pfam PF00072 Response regulator receiver domain 6 112 2.9E-9 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_1c46140 16157845d3933638bcebfbfd697535be 226 SUPERFAMILY SSF46894 149 225 2.18E-22 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 VAPA_1c46140 16157845d3933638bcebfbfd697535be 226 Gene3D G3DSA:3.40.50.2300 4 103 3.5E-11 T 12-10-2018 VAPA_2c12730 acad29382becaa6cc4c5d9c10e502e60 650 Gene3D G3DSA:1.20.144.10 221 341 7.0E-7 T 12-10-2018 VAPA_2c12730 acad29382becaa6cc4c5d9c10e502e60 650 Gene3D G3DSA:1.20.144.10 342 433 7.8E-19 T 12-10-2018 VAPA_2c12730 acad29382becaa6cc4c5d9c10e502e60 650 SUPERFAMILY SSF48317 232 419 5.49E-33 T 12-10-2018 IPR036938 Phosphatidic acid phosphatase type 2/haloperoxidase superfamily VAPA_2c12730 acad29382becaa6cc4c5d9c10e502e60 650 Pfam PF14067 LssY C-terminus 483 601 2.5E-11 T 12-10-2018 IPR025902 LssY-like C-terminal domain VAPA_2c12730 acad29382becaa6cc4c5d9c10e502e60 650 Pfam PF01569 PAP2 superfamily 313 419 2.8E-16 T 12-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase VAPA_2c12730 acad29382becaa6cc4c5d9c10e502e60 650 SMART SM00014 309 419 3.1E-16 T 12-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase VAPA_2c12210 112e2615ef6ce71e8353b09cac9242ee 468 Pfam PF01425 Amidase 25 448 3.7E-107 T 12-10-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 VAPA_2c12210 112e2615ef6ce71e8353b09cac9242ee 468 ProSitePatterns PS00571 Amidases signature. 150 181 - T 12-10-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 VAPA_2c12210 112e2615ef6ce71e8353b09cac9242ee 468 SUPERFAMILY SSF75304 2 458 2.62E-124 T 12-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 VAPA_2c12210 112e2615ef6ce71e8353b09cac9242ee 468 Gene3D G3DSA:3.90.1300.10 7 459 2.4E-133 T 12-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 VAPA_1c51020 7d26775b737388a0c94761c517bfd5a4 125 Gene3D G3DSA:2.40.50.140 1 125 5.6E-63 T 12-10-2018 VAPA_1c51020 7d26775b737388a0c94761c517bfd5a4 125 PRINTS PR01034 Ribosomal protein S12 signature 58 77 6.2E-60 T 12-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 VAPA_1c51020 7d26775b737388a0c94761c517bfd5a4 125 PRINTS PR01034 Ribosomal protein S12 signature 77 94 6.2E-60 T 12-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 VAPA_1c51020 7d26775b737388a0c94761c517bfd5a4 125 PRINTS PR01034 Ribosomal protein S12 signature 110 122 6.2E-60 T 12-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 VAPA_1c51020 7d26775b737388a0c94761c517bfd5a4 125 PRINTS PR01034 Ribosomal protein S12 signature 42 57 6.2E-60 T 12-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 VAPA_1c51020 7d26775b737388a0c94761c517bfd5a4 125 PRINTS PR01034 Ribosomal protein S12 signature 94 110 6.2E-60 T 12-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 VAPA_1c51020 7d26775b737388a0c94761c517bfd5a4 125 PRINTS PR01034 Ribosomal protein S12 signature 27 42 6.2E-60 T 12-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 VAPA_1c51020 7d26775b737388a0c94761c517bfd5a4 125 Hamap MF_00403_B 30S ribosomal protein S12 [rpsL]. 1 123 39.447 T 12-10-2018 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 VAPA_1c51020 7d26775b737388a0c94761c517bfd5a4 125 SUPERFAMILY SSF50249 2 124 1.11E-51 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold VAPA_1c51020 7d26775b737388a0c94761c517bfd5a4 125 Pfam PF00164 Ribosomal protein S12/S23 15 123 7.7E-42 T 12-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 VAPA_1c51020 7d26775b737388a0c94761c517bfd5a4 125 ProSitePatterns PS00055 Ribosomal protein S12 signature. 43 50 - T 12-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 VAPA_1c51020 7d26775b737388a0c94761c517bfd5a4 125 TIGRFAM TIGR00981 rpsL_bact: ribosomal protein uS12 1 124 7.4E-69 T 12-10-2018 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 VAPA_1c51020 7d26775b737388a0c94761c517bfd5a4 125 PIRSF PIRSF002133 1 124 3.7E-54 T 12-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 VAPA_1c14140 c59803263a66522d729f07f7da7fcf15 275 SUPERFAMILY SSF52540 15 225 4.11E-66 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c14140 c59803263a66522d729f07f7da7fcf15 275 Pfam PF00005 ABC transporter 32 172 1.3E-31 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c14140 c59803263a66522d729f07f7da7fcf15 275 ProSitePatterns PS00211 ABC transporters family signature. 145 159 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_1c14140 c59803263a66522d729f07f7da7fcf15 275 SMART SM00382 40 222 2.8E-15 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c14140 c59803263a66522d729f07f7da7fcf15 275 Gene3D G3DSA:3.40.50.300 13 238 6.2E-62 T 12-10-2018 VAPA_1c09720 84de91ea1ea04b90e40d8fb48d5046aa 354 Gene3D G3DSA:3.40.50.2000 160 319 5.4E-109 T 12-10-2018 VAPA_1c09720 84de91ea1ea04b90e40d8fb48d5046aa 354 SUPERFAMILY SSF53756 5 353 3.14E-115 T 12-10-2018 VAPA_1c09720 84de91ea1ea04b90e40d8fb48d5046aa 354 Gene3D G3DSA:3.40.50.2000 7 159 5.4E-109 T 12-10-2018 VAPA_1c09720 84de91ea1ea04b90e40d8fb48d5046aa 354 Hamap MF_00033 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [murG]. 6 353 34.732 T 12-10-2018 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0050511 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 VAPA_1c09720 84de91ea1ea04b90e40d8fb48d5046aa 354 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 183 342 1.6E-36 T 12-10-2018 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-5633231 VAPA_1c09720 84de91ea1ea04b90e40d8fb48d5046aa 354 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 7 143 5.8E-36 T 12-10-2018 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 VAPA_1c09720 84de91ea1ea04b90e40d8fb48d5046aa 354 TIGRFAM TIGR01133 murG: undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase 7 346 1.1E-97 T 12-10-2018 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0050511 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 VAPA_1c53050 1e6e021d6248d14f18ccf83b23d4fc25 406 SUPERFAMILY SSF54106 67 115 1.22E-6 T 12-10-2018 VAPA_1c53050 1e6e021d6248d14f18ccf83b23d4fc25 406 Pfam PF01476 LysM domain 68 114 1.9E-12 T 12-10-2018 IPR018392 LysM domain VAPA_1c53050 1e6e021d6248d14f18ccf83b23d4fc25 406 SMART SM00257 67 116 2.3E-6 T 12-10-2018 IPR018392 LysM domain VAPA_1c53050 1e6e021d6248d14f18ccf83b23d4fc25 406 Gene3D G3DSA:3.10.350.10 66 114 3.6E-13 T 12-10-2018 IPR036779 LysM domain superfamily VAPA_1c34360 c56c8c058ccbb3347e467491f9a5c14c 339 SUPERFAMILY SSF53850 108 290 3.65E-10 T 12-10-2018 VAPA_1c34360 c56c8c058ccbb3347e467491f9a5c14c 339 Gene3D G3DSA:3.40.190.10 134 262 9.9E-44 T 12-10-2018 VAPA_1c34360 c56c8c058ccbb3347e467491f9a5c14c 339 Gene3D G3DSA:3.40.190.150 41 327 9.9E-44 T 12-10-2018 VAPA_1c34360 c56c8c058ccbb3347e467491f9a5c14c 339 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 124 333 4.1E-21 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c34360 c56c8c058ccbb3347e467491f9a5c14c 339 PIRSF PIRSF017082 2 336 1.0E-61 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_2c05600 4127df352b79f1b905c6b0eb7fb79e99 302 Pfam PF03466 LysR substrate binding domain 88 297 5.6E-41 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_2c05600 4127df352b79f1b905c6b0eb7fb79e99 302 Gene3D G3DSA:1.10.10.10 2 89 3.3E-25 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_2c05600 4127df352b79f1b905c6b0eb7fb79e99 302 SUPERFAMILY SSF46785 4 112 7.71E-23 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_2c05600 4127df352b79f1b905c6b0eb7fb79e99 302 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 63 1.5E-19 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_2c05600 4127df352b79f1b905c6b0eb7fb79e99 302 Gene3D G3DSA:3.40.190.10 163 268 1.0E-59 T 12-10-2018 VAPA_2c05600 4127df352b79f1b905c6b0eb7fb79e99 302 Gene3D G3DSA:3.40.190.10 92 294 1.0E-59 T 12-10-2018 VAPA_2c05600 4127df352b79f1b905c6b0eb7fb79e99 302 SUPERFAMILY SSF53850 89 299 2.33E-42 T 12-10-2018 VAPA_2c05600 4127df352b79f1b905c6b0eb7fb79e99 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 2.5E-5 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_2c05600 4127df352b79f1b905c6b0eb7fb79e99 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 2.5E-5 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_2c05600 4127df352b79f1b905c6b0eb7fb79e99 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 2.5E-5 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c09640 2492cb7b3041d20d7da0a524efd51a77 307 SUPERFAMILY SSF53335 7 303 1.45E-40 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase VAPA_1c09640 2492cb7b3041d20d7da0a524efd51a77 307 Gene3D G3DSA:3.40.50.150 10 303 1.9E-97 T 12-10-2018 VAPA_1c09640 2492cb7b3041d20d7da0a524efd51a77 307 TIGRFAM TIGR00006 TIGR00006: 16S rRNA (cytosine(1402)-N(4))-methyltransferase 6 303 8.1E-94 T 12-10-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 VAPA_1c09640 2492cb7b3041d20d7da0a524efd51a77 307 SUPERFAMILY SSF81799 112 212 8.24E-32 T 12-10-2018 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain superfamily GO:0008168 VAPA_1c09640 2492cb7b3041d20d7da0a524efd51a77 307 Hamap MF_01007 Ribosomal RNA small subunit methyltransferase H [rsmH]. 7 304 35.91 T 12-10-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 VAPA_1c09640 2492cb7b3041d20d7da0a524efd51a77 307 Gene3D G3DSA:1.10.150.170 110 213 1.9E-97 T 12-10-2018 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain superfamily GO:0008168 VAPA_1c09640 2492cb7b3041d20d7da0a524efd51a77 307 Pfam PF01795 MraW methylase family 6 303 1.7E-91 T 12-10-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 VAPA_1c09640 2492cb7b3041d20d7da0a524efd51a77 307 PIRSF PIRSF004486 2 305 4.9E-95 T 12-10-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 VAPA_1c14460 c628ea1536c6d7a47dd136cbf52d075d 223 SUPERFAMILY SSF52266 32 223 7.48E-37 T 12-10-2018 VAPA_1c14460 c628ea1536c6d7a47dd136cbf52d075d 223 Gene3D G3DSA:3.40.50.1110 24 223 1.3E-29 T 12-10-2018 IPR036514 SGNH hydrolase superfamily VAPA_1c14460 c628ea1536c6d7a47dd136cbf52d075d 223 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 63 214 1.3E-13 T 12-10-2018 IPR013830 SGNH hydrolase-type esterase domain VAPA_1c12920 0b9d806ccee0c708998aa0e9ed3e2f75 683 Gene3D G3DSA:3.40.605.10 10 487 9.8E-148 T 12-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 VAPA_1c12920 0b9d806ccee0c708998aa0e9ed3e2f75 683 SUPERFAMILY SSF53720 3 504 1.7E-77 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 VAPA_1c12920 0b9d806ccee0c708998aa0e9ed3e2f75 683 SUPERFAMILY SSF54637 529 681 3.23E-42 T 12-10-2018 IPR029069 HotDog domain superfamily VAPA_1c12920 0b9d806ccee0c708998aa0e9ed3e2f75 683 Gene3D G3DSA:3.40.309.10 258 475 9.8E-148 T 12-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 VAPA_1c12920 0b9d806ccee0c708998aa0e9ed3e2f75 683 Gene3D G3DSA:3.10.129.10 529 683 8.1E-47 T 12-10-2018 VAPA_1c12920 0b9d806ccee0c708998aa0e9ed3e2f75 683 Pfam PF01575 MaoC like domain 540 643 5.8E-28 T 12-10-2018 IPR002539 MaoC-like dehydratase domain VAPA_1c12920 0b9d806ccee0c708998aa0e9ed3e2f75 683 Pfam PF00171 Aldehyde dehydrogenase family 20 444 5.3E-58 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 VAPA_1c12920 0b9d806ccee0c708998aa0e9ed3e2f75 683 TIGRFAM TIGR02278 PaaN-DH: phenylacetic acid degradation protein paaN 4 678 1.5E-300 T 12-10-2018 IPR011966 Phenylacetic acid degradation protein PaaN KEGG: 00360+3.3.2.12+1.2.1.91 VAPA_1c02550 bce1ae294d24fdbb14f225e8d4e511de 133 SUPERFAMILY SSF48295 8 57 4.08E-7 T 12-10-2018 IPR010921 Trp repressor/replication initiator GO:0043565 VAPA_1c02550 bce1ae294d24fdbb14f225e8d4e511de 133 Pfam PF01527 Transposase 10 65 1.1E-11 T 12-10-2018 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 VAPA_2c09480 bce1ae294d24fdbb14f225e8d4e511de 133 SUPERFAMILY SSF48295 8 57 4.08E-7 T 12-10-2018 IPR010921 Trp repressor/replication initiator GO:0043565 VAPA_2c09480 bce1ae294d24fdbb14f225e8d4e511de 133 Pfam PF01527 Transposase 10 65 1.1E-11 T 12-10-2018 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 VAPA_1c35000 c6c01a712116769f8d3729a4e5a5c26c 823 Pfam PF00753 Metallo-beta-lactamase superfamily 574 762 1.7E-8 T 12-10-2018 IPR001279 Metallo-beta-lactamase VAPA_1c35000 c6c01a712116769f8d3729a4e5a5c26c 823 Gene3D G3DSA:3.60.15.10 567 793 6.2E-48 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like VAPA_1c35000 c6c01a712116769f8d3729a4e5a5c26c 823 SMART SM00849 575 766 2.1E-12 T 12-10-2018 IPR001279 Metallo-beta-lactamase VAPA_1c35000 c6c01a712116769f8d3729a4e5a5c26c 823 Pfam PF03772 Competence protein 272 537 1.6E-56 T 12-10-2018 IPR004477 ComEC/Rec2-related protein VAPA_1c35000 c6c01a712116769f8d3729a4e5a5c26c 823 TIGRFAM TIGR00360 ComEC_N-term: ComEC/Rec2-related protein 293 477 1.5E-25 T 12-10-2018 IPR004477 ComEC/Rec2-related protein VAPA_1c35000 c6c01a712116769f8d3729a4e5a5c26c 823 TIGRFAM TIGR00361 ComEC_Rec2: DNA internalization-related competence protein ComEC/Rec2 181 790 1.8E-105 T 12-10-2018 IPR004797 Competence protein ComEC/Rec2 GO:0016021|GO:0030420 VAPA_1c35000 c6c01a712116769f8d3729a4e5a5c26c 823 Pfam PF13567 Domain of unknown function (DUF4131) 41 227 4.6E-24 T 12-10-2018 IPR025405 Domain of unknown function DUF4131 VAPA_1c35000 c6c01a712116769f8d3729a4e5a5c26c 823 SUPERFAMILY SSF56281 570 795 5.01E-39 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like VAPA_1c52310 64da07ee0add0feab586491272095def 284 Pfam PF00378 Enoyl-CoA hydratase/isomerase 31 283 2.0E-44 T 12-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 VAPA_1c52310 64da07ee0add0feab586491272095def 284 SUPERFAMILY SSF52096 23 283 5.16E-74 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily VAPA_1c52310 64da07ee0add0feab586491272095def 284 Gene3D G3DSA:1.10.12.10 226 284 2.2E-21 T 12-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal VAPA_1c52310 64da07ee0add0feab586491272095def 284 Gene3D G3DSA:3.90.226.10 11 225 7.3E-65 T 12-10-2018 VAPA_1c52310 64da07ee0add0feab586491272095def 284 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 124 144 - T 12-10-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824 VAPA_1c09730 fc1f22757efece56bddbda16f1d6b115 484 Gene3D G3DSA:3.40.1190.10 94 310 4.3E-78 T 12-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 VAPA_1c09730 fc1f22757efece56bddbda16f1d6b115 484 Pfam PF02875 Mur ligase family, glutamate ligase domain 314 406 5.0E-18 T 12-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 VAPA_1c09730 fc1f22757efece56bddbda16f1d6b115 484 Gene3D G3DSA:3.90.190.20 311 471 2.6E-43 T 12-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 VAPA_1c09730 fc1f22757efece56bddbda16f1d6b115 484 Gene3D G3DSA:3.40.50.720 6 92 4.4E-30 T 12-10-2018 VAPA_1c09730 fc1f22757efece56bddbda16f1d6b115 484 SUPERFAMILY SSF53244 312 462 2.44E-44 T 12-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 VAPA_1c09730 fc1f22757efece56bddbda16f1d6b115 484 Hamap MF_00046 UDP-N-acetylmuramate--L-alanine ligase [murC]. 5 468 42.877 T 12-10-2018 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 VAPA_1c09730 fc1f22757efece56bddbda16f1d6b115 484 SUPERFAMILY SSF51984 6 92 3.27E-28 T 12-10-2018 VAPA_1c09730 fc1f22757efece56bddbda16f1d6b115 484 Pfam PF01225 Mur ligase family, catalytic domain 7 105 1.3E-25 T 12-10-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 VAPA_1c09730 fc1f22757efece56bddbda16f1d6b115 484 SUPERFAMILY SSF53623 91 311 1.57E-69 T 12-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 VAPA_1c09730 fc1f22757efece56bddbda16f1d6b115 484 TIGRFAM TIGR01082 murC: UDP-N-acetylmuramate--L-alanine ligase 7 458 3.6E-161 T 12-10-2018 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 VAPA_1c09730 fc1f22757efece56bddbda16f1d6b115 484 Pfam PF08245 Mur ligase middle domain 110 293 3.0E-26 T 12-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 VAPA_1c52980 4ef2e7dd524ab6233dbe28bc915877f2 325 Pfam PF00753 Metallo-beta-lactamase superfamily 36 226 2.5E-15 T 12-10-2018 IPR001279 Metallo-beta-lactamase VAPA_1c52980 4ef2e7dd524ab6233dbe28bc915877f2 325 Gene3D G3DSA:3.60.15.10 13 245 5.6E-41 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like VAPA_1c52980 4ef2e7dd524ab6233dbe28bc915877f2 325 SMART SM00849 35 227 1.9E-15 T 12-10-2018 IPR001279 Metallo-beta-lactamase VAPA_1c52980 4ef2e7dd524ab6233dbe28bc915877f2 325 SUPERFAMILY SSF56281 17 315 2.94E-54 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like VAPA_1c29220 6b021d022a6bda2a9f66c4829149bf59 239 SMART SM00419 179 227 8.0E-6 T 12-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 VAPA_1c29220 6b021d022a6bda2a9f66c4829149bf59 239 Gene3D G3DSA:1.10.10.10 155 235 7.6E-22 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c29220 6b021d022a6bda2a9f66c4829149bf59 239 Pfam PF13545 Crp-like helix-turn-helix domain 157 233 6.6E-15 T 12-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 VAPA_1c29220 6b021d022a6bda2a9f66c4829149bf59 239 Pfam PF00027 Cyclic nucleotide-binding domain 38 124 1.9E-18 T 12-10-2018 IPR000595 Cyclic nucleotide-binding domain VAPA_1c29220 6b021d022a6bda2a9f66c4829149bf59 239 SMART SM00100 19 137 1.8E-13 T 12-10-2018 IPR000595 Cyclic nucleotide-binding domain VAPA_1c29220 6b021d022a6bda2a9f66c4829149bf59 239 SUPERFAMILY SSF51206 13 150 8.12E-32 T 12-10-2018 IPR018490 Cyclic nucleotide-binding-like VAPA_1c29220 6b021d022a6bda2a9f66c4829149bf59 239 SUPERFAMILY SSF46785 155 236 1.47E-15 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c29220 6b021d022a6bda2a9f66c4829149bf59 239 Gene3D G3DSA:2.60.120.10 7 153 1.5E-28 T 12-10-2018 IPR014710 RmlC-like jelly roll fold VAPA_1c43130 1447f5ebe810cba2bf4d5d698bac651d 316 Pfam PF00691 OmpA family 156 248 2.3E-11 T 12-10-2018 IPR006665 OmpA-like domain VAPA_1c43130 1447f5ebe810cba2bf4d5d698bac651d 316 SUPERFAMILY SSF103088 153 260 3.92E-17 T 12-10-2018 IPR036737 OmpA-like domain superfamily VAPA_1c43130 1447f5ebe810cba2bf4d5d698bac651d 316 Gene3D G3DSA:3.30.1330.60 104 280 2.9E-52 T 12-10-2018 IPR036737 OmpA-like domain superfamily VAPA_1c43130 1447f5ebe810cba2bf4d5d698bac651d 316 Pfam PF13677 Membrane MotB of proton-channel complex MotA/MotB 16 64 2.3E-18 T 12-10-2018 IPR025713 Motility protein B, N-terminal domain VAPA_1c17100 1c5189604e7a9651731b6d6139f0ae84 698 SUPERFAMILY SSF52540 477 692 5.88E-37 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c17100 1c5189604e7a9651731b6d6139f0ae84 698 Pfam PF02224 Cytidylate kinase 479 688 4.8E-64 T 12-10-2018 IPR011994 Cytidylate kinase domain GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 VAPA_1c17100 1c5189604e7a9651731b6d6139f0ae84 698 Hamap MF_00210 3-phosphoshikimate 1-carboxyvinyltransferase [aroA]. 13 473 32.507 T 12-10-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 VAPA_1c17100 1c5189604e7a9651731b6d6139f0ae84 698 Gene3D G3DSA:3.65.10.10 23 259 2.0E-62 T 12-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 VAPA_1c17100 1c5189604e7a9651731b6d6139f0ae84 698 Hamap MF_00238 Cytidylate kinase [cmk]. 477 693 31.644 T 12-10-2018 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 VAPA_1c17100 1c5189604e7a9651731b6d6139f0ae84 698 ProSitePatterns PS00104 EPSP synthase signature 1. 92 106 - T 12-10-2018 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 VAPA_1c17100 1c5189604e7a9651731b6d6139f0ae84 698 Gene3D G3DSA:3.65.10.10 264 471 2.1E-64 T 12-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 VAPA_1c17100 1c5189604e7a9651731b6d6139f0ae84 698 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 16 191 2.2E-49 T 12-10-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 VAPA_1c17100 1c5189604e7a9651731b6d6139f0ae84 698 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 224 467 2.5E-66 T 12-10-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 VAPA_1c17100 1c5189604e7a9651731b6d6139f0ae84 698 TIGRFAM TIGR00017 cmk: cytidylate kinase 477 687 1.9E-65 T 12-10-2018 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 VAPA_1c17100 1c5189604e7a9651731b6d6139f0ae84 698 SUPERFAMILY SSF55205 12 469 1.06E-108 T 12-10-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 VAPA_1c17100 1c5189604e7a9651731b6d6139f0ae84 698 Gene3D G3DSA:3.40.50.300 473 696 7.5E-70 T 12-10-2018 VAPA_1c17100 1c5189604e7a9651731b6d6139f0ae84 698 ProSitePatterns PS00885 EPSP synthase signature 2. 381 399 - T 12-10-2018 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 VAPA_1c27940 4a1b4ec70e78357edb68c922b66d2593 538 SUPERFAMILY SSF54810 412 538 4.45E-47 T 12-10-2018 VAPA_1c27940 4a1b4ec70e78357edb68c922b66d2593 538 Gene3D G3DSA:3.30.300.10 413 538 8.8E-51 T 12-10-2018 VAPA_1c27940 4a1b4ec70e78357edb68c922b66d2593 538 Pfam PF00958 GMP synthase C terminal domain 452 537 1.2E-41 T 12-10-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 VAPA_1c27940 4a1b4ec70e78357edb68c922b66d2593 538 TIGRFAM TIGR00884 guaA_Cterm: GMP synthase (glutamine-hydrolyzing), C-terminal domain 214 538 1.3E-141 T 12-10-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 VAPA_1c27940 4a1b4ec70e78357edb68c922b66d2593 538 SUPERFAMILY SSF52317 3 237 1.43E-52 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like VAPA_1c27940 4a1b4ec70e78357edb68c922b66d2593 538 TIGRFAM TIGR00888 guaA_Nterm: GMP synthase (glutamine-hydrolyzing), N-terminal domain 6 204 1.3E-68 T 12-10-2018 IPR004739 GMP synthase, glutamine amidotransferase GO:0003922|GO:0005524|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 VAPA_1c27940 4a1b4ec70e78357edb68c922b66d2593 538 Gene3D G3DSA:3.40.50.880 5 206 6.7E-50 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like VAPA_1c27940 4a1b4ec70e78357edb68c922b66d2593 538 Hamap MF_00344 GMP synthase [glutamine-hydrolyzing] [guaA]. 3 538 53.897 T 12-10-2018 IPR022955 GMP synthase GO:0003922|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221 VAPA_1c27940 4a1b4ec70e78357edb68c922b66d2593 538 Gene3D G3DSA:3.40.50.620 210 412 5.3E-74 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold VAPA_1c27940 4a1b4ec70e78357edb68c922b66d2593 538 Pfam PF00117 Glutamine amidotransferase class-I 8 199 3.4E-33 T 12-10-2018 IPR017926 Glutamine amidotransferase VAPA_1c27940 4a1b4ec70e78357edb68c922b66d2593 538 Pfam PF02540 NAD synthase 219 254 1.3E-6 T 12-10-2018 IPR022310 NAD/GMP synthase VAPA_1c27940 4a1b4ec70e78357edb68c922b66d2593 538 SUPERFAMILY SSF52402 197 427 7.94E-56 T 12-10-2018 VAPA_1c10360 7dc1206e73e159a1867560a68da15159 308 SUPERFAMILY SSF53067 4 305 5.68E-45 T 12-10-2018 VAPA_1c10360 7dc1206e73e159a1867560a68da15159 308 Gene3D G3DSA:3.30.420.40 5 299 2.4E-57 T 12-10-2018 VAPA_1c10360 7dc1206e73e159a1867560a68da15159 308 Gene3D G3DSA:3.30.420.40 141 291 2.4E-57 T 12-10-2018 VAPA_1c10360 7dc1206e73e159a1867560a68da15159 308 Pfam PF00480 ROK family 3 306 1.9E-34 T 12-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 VAPA_1c49610 cf9e5c47c1ebf6c48574fbd4092f79e8 418 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 347 362 1.8E-10 T 12-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 VAPA_1c49610 cf9e5c47c1ebf6c48574fbd4092f79e8 418 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 297 310 1.8E-10 T 12-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 VAPA_1c49610 cf9e5c47c1ebf6c48574fbd4092f79e8 418 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 30 46 1.8E-10 T 12-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 VAPA_1c49610 cf9e5c47c1ebf6c48574fbd4092f79e8 418 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 52 68 1.8E-10 T 12-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 VAPA_1c49610 cf9e5c47c1ebf6c48574fbd4092f79e8 418 Gene3D G3DSA:3.40.50.2300 31 370 7.9E-132 T 12-10-2018 VAPA_1c49610 cf9e5c47c1ebf6c48574fbd4092f79e8 418 SUPERFAMILY SSF53822 29 388 1.07E-66 T 12-10-2018 IPR028082 Periplasmic binding protein-like I VAPA_1c49610 cf9e5c47c1ebf6c48574fbd4092f79e8 418 Pfam PF13458 Periplasmic binding protein 29 377 6.7E-63 T 12-10-2018 IPR028081 Leucine-binding protein domain VAPA_1c49610 cf9e5c47c1ebf6c48574fbd4092f79e8 418 Gene3D G3DSA:3.40.50.2300 158 413 7.9E-132 T 12-10-2018 VAPA_1c10530 6ec52a3894abe88e10b96f6a3d73af31 134 SMART SM01034 7 99 5.3E-36 T 12-10-2018 IPR007024 BLUF domain GO:0009882|GO:0071949 VAPA_1c10530 6ec52a3894abe88e10b96f6a3d73af31 134 SUPERFAMILY SSF54975 7 107 5.23E-32 T 12-10-2018 IPR036046 Acylphosphatase-like domain superfamily KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 VAPA_1c10530 6ec52a3894abe88e10b96f6a3d73af31 134 Gene3D G3DSA:3.30.70.3200 1 125 9.8E-33 T 12-10-2018 VAPA_1c10530 6ec52a3894abe88e10b96f6a3d73af31 134 Pfam PF04940 Sensors of blue-light using FAD 7 98 5.6E-25 T 12-10-2018 IPR007024 BLUF domain GO:0009882|GO:0071949 VAPA_1c38990 dcd844781342dad682a255fb81c8d9ab 161 Gene3D G3DSA:3.30.70.990 9 98 6.8E-57 T 12-10-2018 IPR035570 UPF0234, N-terminal VAPA_1c38990 dcd844781342dad682a255fb81c8d9ab 161 SUPERFAMILY SSF89963 2 87 1.14E-27 T 12-10-2018 IPR036183 YajQ-like superfamily VAPA_1c38990 dcd844781342dad682a255fb81c8d9ab 161 Pfam PF04461 Protein of unknown function (DUF520) 2 160 1.1E-64 T 12-10-2018 IPR007551 Protein of unknown function DUF520 VAPA_1c38990 dcd844781342dad682a255fb81c8d9ab 161 Gene3D G3DSA:3.30.70.860 3 160 6.8E-57 T 12-10-2018 IPR035571 UPF0234-like, C-terminal VAPA_1c38990 dcd844781342dad682a255fb81c8d9ab 161 Hamap MF_00632 UPF0234 protein YajQ [yajQ]. 1 161 27.6 T 12-10-2018 IPR007551 Protein of unknown function DUF520 VAPA_1c38990 dcd844781342dad682a255fb81c8d9ab 161 SUPERFAMILY SSF89963 89 161 3.14E-27 T 12-10-2018 IPR036183 YajQ-like superfamily VAPA_1c35860 3b58f027146d05f5e9d9c34f62ccbea6 888 Gene3D G3DSA:1.10.439.10 40 193 9.8E-45 T 12-10-2018 IPR023343 Penicillin amidase type, domain 1 GO:0016811 VAPA_1c35860 3b58f027146d05f5e9d9c34f62ccbea6 888 PIRSF PIRSF001227 26 831 1.3E-215 T 12-10-2018 IPR014395 Penicillin/GL-7-ACA/AHL acylase GO:0016811 VAPA_1c35860 3b58f027146d05f5e9d9c34f62ccbea6 888 Gene3D G3DSA:2.30.120.10 379 448 1.0E-163 T 12-10-2018 VAPA_1c35860 3b58f027146d05f5e9d9c34f62ccbea6 888 Gene3D G3DSA:1.10.1400.10 604 729 1.0E-163 T 12-10-2018 VAPA_1c35860 3b58f027146d05f5e9d9c34f62ccbea6 888 Pfam PF01804 Penicillin amidase 58 829 2.5E-213 T 12-10-2018 IPR002692 Penicillin/GL-7-ACA/AHL/aculeacin-A acylase GO:0016787|GO:0017000 VAPA_1c35860 3b58f027146d05f5e9d9c34f62ccbea6 888 SUPERFAMILY SSF56235 54 829 1.16E-200 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal VAPA_1c35860 3b58f027146d05f5e9d9c34f62ccbea6 888 Gene3D G3DSA:3.60.20.10 307 820 1.0E-163 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal VAPA_1c29410 14ec2751450e425a384daaee99c7c058 262 Gene3D G3DSA:2.160.10.10 1 191 1.4E-50 T 12-10-2018 VAPA_1c29410 14ec2751450e425a384daaee99c7c058 262 SUPERFAMILY SSF51161 2 260 2.75E-74 T 12-10-2018 IPR011004 Trimeric LpxA-like superfamily VAPA_1c29410 14ec2751450e425a384daaee99c7c058 262 Hamap MF_00387 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase [lpxA]. 1 262 44.0 T 12-10-2018 IPR010137 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase GO:0008610|GO:0008780 KEGG: 00540+2.3.1.129 VAPA_1c29410 14ec2751450e425a384daaee99c7c058 262 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 149 177 - T 12-10-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 VAPA_1c29410 14ec2751450e425a384daaee99c7c058 262 Gene3D G3DSA:1.20.1180.10 193 262 2.7E-19 T 12-10-2018 IPR037157 UDP-N-acetylglucosamine O-acyltransferase, C-terminal domain superfamily KEGG: 00540+2.3.1.129 VAPA_1c29410 14ec2751450e425a384daaee99c7c058 262 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 2 35 2.1E-4 T 12-10-2018 IPR001451 Hexapeptide repeat VAPA_1c29410 14ec2751450e425a384daaee99c7c058 262 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 105 139 3.0E-7 T 12-10-2018 IPR001451 Hexapeptide repeat VAPA_1c29410 14ec2751450e425a384daaee99c7c058 262 Pfam PF13720 Udp N-acetylglucosamine O-acyltransferase; Domain 2 176 260 2.0E-24 T 12-10-2018 IPR029098 UDP N-acetylglucosamine O-acyltransferase, C-terminal KEGG: 00540+2.3.1.129 VAPA_1c29410 14ec2751450e425a384daaee99c7c058 262 TIGRFAM TIGR01852 lipid_A_lpxA: acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase 4 260 4.7E-95 T 12-10-2018 IPR010137 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase GO:0008610|GO:0008780 KEGG: 00540+2.3.1.129 VAPA_1c29410 14ec2751450e425a384daaee99c7c058 262 PIRSF PIRSF000456 1 262 1.6E-95 T 12-10-2018 IPR010137 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase GO:0008610|GO:0008780 KEGG: 00540+2.3.1.129 VAPA_1c18890 fc0624496d12c1de20c71eca9296c3f5 233 Pfam PF01027 Inhibitor of apoptosis-promoting Bax1 25 225 1.2E-40 T 12-10-2018 IPR006214 Bax inhibitor 1-related VAPA_1c53130 ccdc16a5605a79d6d7dc8fdab93b69ff 158 SUPERFAMILY SSF46785 4 63 2.12E-19 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c53130 ccdc16a5605a79d6d7dc8fdab93b69ff 158 SMART SM00344 4 113 8.5E-43 T 12-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 VAPA_1c53130 ccdc16a5605a79d6d7dc8fdab93b69ff 158 Pfam PF01037 Lrp/AsnC ligand binding domain 70 142 8.3E-18 T 12-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain VAPA_1c53130 ccdc16a5605a79d6d7dc8fdab93b69ff 158 ProSitePatterns PS00519 AsnC-type HTH domain signature. 22 48 - T 12-10-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site VAPA_1c53130 ccdc16a5605a79d6d7dc8fdab93b69ff 158 Gene3D G3DSA:3.30.70.920 57 141 1.5E-22 T 12-10-2018 VAPA_1c53130 ccdc16a5605a79d6d7dc8fdab93b69ff 158 Pfam PF13412 Winged helix-turn-helix DNA-binding 5 51 1.2E-20 T 12-10-2018 VAPA_1c53130 ccdc16a5605a79d6d7dc8fdab93b69ff 158 SUPERFAMILY SSF54909 64 153 5.9E-17 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel VAPA_1c53130 ccdc16a5605a79d6d7dc8fdab93b69ff 158 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 20 31 2.5E-17 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 VAPA_1c53130 ccdc16a5605a79d6d7dc8fdab93b69ff 158 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 4 20 2.5E-17 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 VAPA_1c53130 ccdc16a5605a79d6d7dc8fdab93b69ff 158 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 31 50 2.5E-17 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 VAPA_1c53130 ccdc16a5605a79d6d7dc8fdab93b69ff 158 Gene3D G3DSA:1.10.10.10 5 55 7.9E-26 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c54740 d6b343b019889cd24a5e7703fe94ac5d 453 Pfam PF13449 Esterase-like activity of phytase 92 424 5.7E-67 T 12-10-2018 IPR027372 Phytase-like domain VAPA_1c43740 78f657c9a1b82c7b5ff43615ff97bc00 85 ProSitePatterns PS00831 Ribosomal protein L27 signature. 34 48 - T 12-10-2018 IPR018261 Ribosomal protein L27, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 VAPA_1c43740 78f657c9a1b82c7b5ff43615ff97bc00 85 Pfam PF01016 Ribosomal L27 protein 2 82 1.4E-36 T 12-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 VAPA_1c43740 78f657c9a1b82c7b5ff43615ff97bc00 85 Gene3D G3DSA:2.40.50.100 21 85 4.0E-28 T 12-10-2018 VAPA_1c43740 78f657c9a1b82c7b5ff43615ff97bc00 85 SUPERFAMILY SSF110324 2 81 8.37E-33 T 12-10-2018 VAPA_1c43740 78f657c9a1b82c7b5ff43615ff97bc00 85 ProDom PD003114 RIBOSOMAL L27 50S RIBONUCLEOPROTEIN CHLOROPLAST MITOCHONDRIAL PEPTIDE 60S TRANSIT PRECURSOR 28 69 3.0E-16 T 12-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 VAPA_1c43740 78f657c9a1b82c7b5ff43615ff97bc00 85 TIGRFAM TIGR00062 L27: ribosomal protein bL27 1 82 1.5E-36 T 12-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 VAPA_1c43740 78f657c9a1b82c7b5ff43615ff97bc00 85 Hamap MF_00539 50S ribosomal protein L27 [rpmA]. 1 85 27.694 T 12-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 VAPA_1c43740 78f657c9a1b82c7b5ff43615ff97bc00 85 PRINTS PR00063 Ribosomal protein L27 signature 54 78 3.5E-37 T 12-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 VAPA_1c43740 78f657c9a1b82c7b5ff43615ff97bc00 85 PRINTS PR00063 Ribosomal protein L27 signature 4 28 3.5E-37 T 12-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 VAPA_1c43740 78f657c9a1b82c7b5ff43615ff97bc00 85 PRINTS PR00063 Ribosomal protein L27 signature 29 53 3.5E-37 T 12-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 VAPA_2c08970 960eed69c769cc415da342b419dc923e 396 Gene3D G3DSA:1.20.1250.20 12 193 2.6E-14 T 12-10-2018 VAPA_2c08970 960eed69c769cc415da342b419dc923e 396 Gene3D G3DSA:1.20.1250.20 205 391 2.0E-14 T 12-10-2018 VAPA_2c08970 960eed69c769cc415da342b419dc923e 396 SUPERFAMILY SSF103473 9 389 1.44E-39 T 12-10-2018 IPR036259 MFS transporter superfamily VAPA_2c08970 960eed69c769cc415da342b419dc923e 396 Pfam PF07690 Major Facilitator Superfamily 22 350 4.8E-21 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 VAPA_1c46330 c12ce4aafc4dae1546082d242c52e69d 614 Pfam PF00664 ABC transporter transmembrane region 56 302 1.7E-17 T 12-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 VAPA_1c46330 c12ce4aafc4dae1546082d242c52e69d 614 ProSitePatterns PS00211 ABC transporters family signature. 491 505 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_1c46330 c12ce4aafc4dae1546082d242c52e69d 614 Gene3D G3DSA:3.40.50.300 347 593 2.6E-63 T 12-10-2018 VAPA_1c46330 c12ce4aafc4dae1546082d242c52e69d 614 SUPERFAMILY SSF90123 41 340 2.88E-34 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 VAPA_1c46330 c12ce4aafc4dae1546082d242c52e69d 614 Pfam PF00005 ABC transporter 370 519 7.8E-27 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c46330 c12ce4aafc4dae1546082d242c52e69d 614 Gene3D G3DSA:1.20.1560.10 38 339 5.1E-34 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 VAPA_1c46330 c12ce4aafc4dae1546082d242c52e69d 614 SUPERFAMILY SSF52540 343 574 4.71E-59 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c46330 c12ce4aafc4dae1546082d242c52e69d 614 SMART SM00382 379 571 4.3E-7 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c54700 17c27a307b77dcd5c796f98d57f879b8 126 Pfam PF02675 S-adenosylmethionine decarboxylase 5 122 2.4E-25 T 12-10-2018 IPR003826 S-adenosylmethionine decarboxylase family, prokaryotic GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 VAPA_1c54700 17c27a307b77dcd5c796f98d57f879b8 126 SUPERFAMILY SSF56276 2 124 1.1E-24 T 12-10-2018 IPR016067 S-adenosylmethionine decarboxylase, core GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834|Reactome: R-HSA-351202 VAPA_1c54700 17c27a307b77dcd5c796f98d57f879b8 126 Gene3D G3DSA:3.60.90.10 1 126 1.5E-32 T 12-10-2018 VAPA_1c54700 17c27a307b77dcd5c796f98d57f879b8 126 TIGRFAM TIGR03330 SAM_DCase_Bsu: S-adenosylmethionine decarboxylase proenzyme 2 122 2.3E-23 T 12-10-2018 IPR017716 S-adenosylmethionine decarboxylase proenzyme GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 VAPA_1c54460 17ffc9beb52842af2af2cf0d2babf6de 263 SUPERFAMILY SSF53639 14 230 1.84E-64 T 12-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily VAPA_1c54460 17ffc9beb52842af2af2cf0d2babf6de 263 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 23 203 3.8E-47 T 12-10-2018 IPR001303 Class II aldolase/adducin N-terminal VAPA_1c54460 17ffc9beb52842af2af2cf0d2babf6de 263 Gene3D G3DSA:3.40.225.10 10 263 1.2E-77 T 12-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily VAPA_1c54460 17ffc9beb52842af2af2cf0d2babf6de 263 SMART SM01007 22 203 4.3E-67 T 12-10-2018 IPR001303 Class II aldolase/adducin N-terminal VAPA_1c08880 df0908d30425f525590895a650d809d3 300 Gene3D G3DSA:3.40.190.10 24 268 9.3E-86 T 12-10-2018 VAPA_1c08880 df0908d30425f525590895a650d809d3 300 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 44 263 1.0E-45 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF VAPA_1c08880 df0908d30425f525590895a650d809d3 300 SMART SM00062 34 265 4.0E-46 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF VAPA_1c08880 df0908d30425f525590895a650d809d3 300 SUPERFAMILY SSF53850 3 266 2.69E-58 T 12-10-2018 VAPA_1c08880 df0908d30425f525590895a650d809d3 300 Gene3D G3DSA:3.40.190.10 127 222 9.3E-86 T 12-10-2018 VAPA_1c05180 20eac4092fd148f8b1d71c7bc71e65b3 432 Pfam PF10005 zinc-ribbon domain 33 146 3.2E-18 T 12-10-2018 IPR011201 Zinc-ribbon domain, bacteria VAPA_1c05180 20eac4092fd148f8b1d71c7bc71e65b3 432 Pfam PF15887 Putative zinc-binding metallo-peptidase 152 399 1.0E-104 T 12-10-2018 IPR031321 Uncharacterised conserved protein UCP012641, putative zinc-binding metallo-peptidase VAPA_1c05180 20eac4092fd148f8b1d71c7bc71e65b3 432 PIRSF PIRSF012641 30 414 1.2E-122 T 12-10-2018 IPR031321 Uncharacterised conserved protein UCP012641, putative zinc-binding metallo-peptidase VAPA_1c48240 4c9f38113efd27144ff0d7aca3da9723 410 SMART SM00363 349 410 0.0027 T 12-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VAPA_1c48240 4c9f38113efd27144ff0d7aca3da9723 410 Hamap MF_02007 Tyrosine--tRNA ligase [tyrS]. 13 409 46.564 T 12-10-2018 IPR024108 Tyrosine-tRNA ligase, bacterial-type, type 2 GO:0004831 KEGG: 00970+6.1.1.1 VAPA_1c48240 4c9f38113efd27144ff0d7aca3da9723 410 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 226 238 6.2E-25 T 12-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 VAPA_1c48240 4c9f38113efd27144ff0d7aca3da9723 410 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 176 191 6.2E-25 T 12-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 VAPA_1c48240 4c9f38113efd27144ff0d7aca3da9723 410 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 193 215 6.2E-25 T 12-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 VAPA_1c48240 4c9f38113efd27144ff0d7aca3da9723 410 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 61 83 6.2E-25 T 12-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 VAPA_1c48240 4c9f38113efd27144ff0d7aca3da9723 410 Pfam PF01479 S4 domain 351 391 1.4E-5 T 12-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VAPA_1c48240 4c9f38113efd27144ff0d7aca3da9723 410 SUPERFAMILY SSF52374 20 327 5.09E-89 T 12-10-2018 VAPA_1c48240 4c9f38113efd27144ff0d7aca3da9723 410 Gene3D G3DSA:1.10.240.10 234 339 2.5E-29 T 12-10-2018 VAPA_1c48240 4c9f38113efd27144ff0d7aca3da9723 410 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 57 67 - T 12-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 VAPA_1c48240 4c9f38113efd27144ff0d7aca3da9723 410 Pfam PF00579 tRNA synthetases class I (W and Y) 47 328 1.4E-75 T 12-10-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 VAPA_1c48240 4c9f38113efd27144ff0d7aca3da9723 410 Gene3D G3DSA:3.10.290.10 340 409 7.4E-16 T 12-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 VAPA_1c48240 4c9f38113efd27144ff0d7aca3da9723 410 Gene3D G3DSA:3.40.50.620 14 233 3.7E-69 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold VAPA_1c48240 4c9f38113efd27144ff0d7aca3da9723 410 SUPERFAMILY SSF55174 312 408 4.56E-16 T 12-10-2018 VAPA_1c48240 4c9f38113efd27144ff0d7aca3da9723 410 TIGRFAM TIGR00234 tyrS: tyrosine--tRNA ligase 18 409 2.5E-116 T 12-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 VAPA_1c15070 47f7a14efc10eddd87644580c47ed2b5 281 TIGRFAM TIGR00262 trpA: tryptophan synthase, alpha subunit 8 261 5.3E-69 T 12-10-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 VAPA_1c15070 47f7a14efc10eddd87644580c47ed2b5 281 ProSitePatterns PS00167 Tryptophan synthase alpha chain signature. 48 61 - T 12-10-2018 IPR018204 Tryptophan synthase, alpha chain, active site GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 VAPA_1c15070 47f7a14efc10eddd87644580c47ed2b5 281 Pfam PF00290 Tryptophan synthase alpha chain 8 251 1.8E-80 T 12-10-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 VAPA_1c15070 47f7a14efc10eddd87644580c47ed2b5 281 Hamap MF_00131 Tryptophan synthase alpha chain [trpA]. 14 266 33.139 T 12-10-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 VAPA_1c15070 47f7a14efc10eddd87644580c47ed2b5 281 Gene3D G3DSA:3.20.20.70 1 273 3.8E-95 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 VAPA_1c15070 47f7a14efc10eddd87644580c47ed2b5 281 SUPERFAMILY SSF51366 1 254 3.39E-86 T 12-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 VAPA_1c07180 ed0326ae92d8140cfae07e5f774bdacf 97 Pfam PF00501 AMP-binding enzyme 8 86 1.0E-15 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 VAPA_1c07180 ed0326ae92d8140cfae07e5f774bdacf 97 Gene3D G3DSA:3.40.50.12780 2 96 6.5E-18 T 12-10-2018 VAPA_1c07180 ed0326ae92d8140cfae07e5f774bdacf 97 SUPERFAMILY SSF56801 3 86 4.19E-19 T 12-10-2018 VAPA_1c39700 f07e6e76ca833abb3ff010bd9c302b8d 154 Gene3D G3DSA:3.40.630.30 4 152 1.4E-34 T 12-10-2018 VAPA_1c39700 f07e6e76ca833abb3ff010bd9c302b8d 154 Pfam PF00583 Acetyltransferase (GNAT) family 45 140 2.8E-14 T 12-10-2018 IPR000182 GNAT domain VAPA_1c39700 f07e6e76ca833abb3ff010bd9c302b8d 154 SUPERFAMILY SSF55729 7 141 1.86E-28 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase VAPA_2c05530 379f80b39cbb3b528c3ba5dbe1a89889 356 Pfam PF13358 DDE superfamily endonuclease 1 66 2.0E-8 T 12-10-2018 IPR038717 Tc1-like transposase, DDE domain VAPA_1c38510 0b3ea092e9aef7b3147817f83e7debea 533 SUPERFAMILY SSF46689 113 148 1.83E-5 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 VAPA_1c38510 0b3ea092e9aef7b3147817f83e7debea 533 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 151 193 - T 12-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 VAPA_1c38510 0b3ea092e9aef7b3147817f83e7debea 533 Pfam PF12833 Helix-turn-helix domain 120 198 1.2E-24 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 VAPA_1c38510 0b3ea092e9aef7b3147817f83e7debea 533 SUPERFAMILY SSF48150 330 503 3.49E-44 T 12-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 VAPA_1c38510 0b3ea092e9aef7b3147817f83e7debea 533 SUPERFAMILY SSF55945 212 324 1.73E-17 T 12-10-2018 VAPA_1c38510 0b3ea092e9aef7b3147817f83e7debea 533 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 346 475 9.3E-10 T 12-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 VAPA_1c38510 0b3ea092e9aef7b3147817f83e7debea 533 SUPERFAMILY SSF57884 10 88 1.96E-30 T 12-10-2018 IPR035451 Ada-like domain superfamily VAPA_1c38510 0b3ea092e9aef7b3147817f83e7debea 533 SMART SM01009 211 340 1.3E-36 T 12-10-2018 IPR010316 DNA-3-methyladenine glycosylase AlkA, N-terminal VAPA_1c38510 0b3ea092e9aef7b3147817f83e7debea 533 SUPERFAMILY SSF46689 150 199 9.41E-10 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 VAPA_1c38510 0b3ea092e9aef7b3147817f83e7debea 533 Gene3D G3DSA:1.10.1670.10 461 512 1.6E-13 T 12-10-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 VAPA_1c38510 0b3ea092e9aef7b3147817f83e7debea 533 SMART SM00478 350 506 1.6E-16 T 12-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 VAPA_1c38510 0b3ea092e9aef7b3147817f83e7debea 533 Gene3D G3DSA:1.10.340.30 341 459 8.9E-34 T 12-10-2018 VAPA_1c38510 0b3ea092e9aef7b3147817f83e7debea 533 Gene3D G3DSA:1.10.10.60 101 201 1.0E-23 T 12-10-2018 VAPA_1c38510 0b3ea092e9aef7b3147817f83e7debea 533 Pfam PF06029 AlkA N-terminal domain 212 340 5.5E-27 T 12-10-2018 IPR010316 DNA-3-methyladenine glycosylase AlkA, N-terminal VAPA_1c38510 0b3ea092e9aef7b3147817f83e7debea 533 Gene3D G3DSA:3.40.10.10 6 81 2.7E-29 T 12-10-2018 IPR035451 Ada-like domain superfamily VAPA_1c38510 0b3ea092e9aef7b3147817f83e7debea 533 Pfam PF02805 Metal binding domain of Ada 16 79 1.1E-28 T 12-10-2018 IPR004026 Ada DNA repair, metal-binding GO:0003677|GO:0006281|GO:0006355|GO:0008168|GO:0008270 VAPA_1c38510 0b3ea092e9aef7b3147817f83e7debea 533 Gene3D G3DSA:3.30.310.20 212 340 3.3E-26 T 12-10-2018 IPR037046 DNA-3-methyladenine glycosylase AlkA, N-terminal domain superfamily VAPA_1c38510 0b3ea092e9aef7b3147817f83e7debea 533 SMART SM00342 114 197 1.8E-28 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 VAPA_1c38340 cd13ca1f6a9879b3797e75aa63adc29e 183 SUPERFAMILY SSF103088 85 181 3.27E-16 T 12-10-2018 IPR036737 OmpA-like domain superfamily VAPA_1c38340 cd13ca1f6a9879b3797e75aa63adc29e 183 Pfam PF00691 OmpA family 88 159 2.0E-11 T 12-10-2018 IPR006665 OmpA-like domain VAPA_1c38340 cd13ca1f6a9879b3797e75aa63adc29e 183 Gene3D G3DSA:3.30.1330.60 58 182 8.0E-15 T 12-10-2018 IPR036737 OmpA-like domain superfamily VAPA_1c32470 04cf787ae33a680b76bc2e5b47aaf13c 347 SUPERFAMILY SSF55961 138 337 3.85E-39 T 12-10-2018 VAPA_1c32470 04cf787ae33a680b76bc2e5b47aaf13c 347 Pfam PF00355 Rieske [2Fe-2S] domain 25 103 7.7E-17 T 12-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 VAPA_1c32470 04cf787ae33a680b76bc2e5b47aaf13c 347 Gene3D G3DSA:3.30.530.90 152 345 5.1E-7 T 12-10-2018 VAPA_1c32470 04cf787ae33a680b76bc2e5b47aaf13c 347 Gene3D G3DSA:2.102.10.10 21 151 8.1E-31 T 12-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 VAPA_1c32470 04cf787ae33a680b76bc2e5b47aaf13c 347 SUPERFAMILY SSF50022 14 133 3.4E-29 T 12-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 VAPA_1c32390 27a1672454c1acae566b535eeae71c38 302 Pfam PF00892 EamA-like transporter family 154 287 2.3E-12 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 VAPA_1c32390 27a1672454c1acae566b535eeae71c38 302 Pfam PF00892 EamA-like transporter family 9 140 2.2E-6 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 VAPA_1c32390 27a1672454c1acae566b535eeae71c38 302 SUPERFAMILY SSF103481 44 145 5.89E-9 T 12-10-2018 VAPA_1c32390 27a1672454c1acae566b535eeae71c38 302 SUPERFAMILY SSF103481 189 287 4.58E-9 T 12-10-2018 VAPA_1c35790 a0584aace3a88ceef0d6d7cea4d609ca 234 Pfam PF07729 FCD domain 87 205 4.9E-20 T 12-10-2018 IPR011711 GntR, C-terminal VAPA_1c35790 a0584aace3a88ceef0d6d7cea4d609ca 234 SMART SM00895 86 206 3.8E-16 T 12-10-2018 IPR011711 GntR, C-terminal VAPA_1c35790 a0584aace3a88ceef0d6d7cea4d609ca 234 SUPERFAMILY SSF46785 13 102 9.66E-18 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c35790 a0584aace3a88ceef0d6d7cea4d609ca 234 SMART SM00345 18 76 2.6E-10 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_1c35790 a0584aace3a88ceef0d6d7cea4d609ca 234 Pfam PF00392 Bacterial regulatory proteins, gntR family 15 76 3.3E-14 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_1c35790 a0584aace3a88ceef0d6d7cea4d609ca 234 SUPERFAMILY SSF48008 84 211 6.02E-25 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal VAPA_1c35790 a0584aace3a88ceef0d6d7cea4d609ca 234 Gene3D G3DSA:1.20.120.530 76 221 3.0E-25 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal VAPA_1c35790 a0584aace3a88ceef0d6d7cea4d609ca 234 Gene3D G3DSA:1.10.10.10 12 75 1.4E-19 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c17310 d50889f60cbaebfbffc7366b4cb5a21b 578 Pfam PF01019 Gamma-glutamyltranspeptidase 54 571 1.6E-183 T 12-10-2018 VAPA_1c17310 d50889f60cbaebfbffc7366b4cb5a21b 578 Gene3D G3DSA:1.10.246.130 266 378 6.5E-42 T 12-10-2018 VAPA_1c17310 d50889f60cbaebfbffc7366b4cb5a21b 578 SUPERFAMILY SSF56235 32 578 1.6E-181 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal VAPA_1c17310 d50889f60cbaebfbffc7366b4cb5a21b 578 ProSitePatterns PS00462 Gamma-glutamyltranspeptidase signature. 379 403 - T 12-10-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-4061|MetaCyc: PWY-5826|MetaCyc: PWY-6842|MetaCyc: PWY-7112|MetaCyc: PWY-7559 VAPA_1c17310 d50889f60cbaebfbffc7366b4cb5a21b 578 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 134 152 1.2E-80 T 12-10-2018 VAPA_1c17310 d50889f60cbaebfbffc7366b4cb5a21b 578 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 152 171 1.2E-80 T 12-10-2018 VAPA_1c17310 d50889f60cbaebfbffc7366b4cb5a21b 578 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 250 266 1.2E-80 T 12-10-2018 VAPA_1c17310 d50889f60cbaebfbffc7366b4cb5a21b 578 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 444 459 1.2E-80 T 12-10-2018 VAPA_1c17310 d50889f60cbaebfbffc7366b4cb5a21b 578 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 468 485 1.2E-80 T 12-10-2018 VAPA_1c17310 d50889f60cbaebfbffc7366b4cb5a21b 578 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 403 421 1.2E-80 T 12-10-2018 VAPA_1c17310 d50889f60cbaebfbffc7366b4cb5a21b 578 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 280 299 1.2E-80 T 12-10-2018 VAPA_1c17310 d50889f60cbaebfbffc7366b4cb5a21b 578 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 379 397 1.2E-80 T 12-10-2018 VAPA_1c17310 d50889f60cbaebfbffc7366b4cb5a21b 578 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 61 86 1.2E-80 T 12-10-2018 VAPA_1c17310 d50889f60cbaebfbffc7366b4cb5a21b 578 TIGRFAM TIGR00066 g_glut_trans: gamma-glutamyltransferase 39 540 9.9E-175 T 12-10-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-4061|MetaCyc: PWY-5826|MetaCyc: PWY-6842|MetaCyc: PWY-7112|MetaCyc: PWY-7559 VAPA_1c17310 d50889f60cbaebfbffc7366b4cb5a21b 578 Gene3D G3DSA:3.60.20.40 379 578 1.7E-71 T 12-10-2018 VAPA_1c51610 1d713122eede790bba77e69368f175ef 569 Gene3D G3DSA:1.20.140.10 294 452 1.8E-34 T 12-10-2018 VAPA_1c51610 1d713122eede790bba77e69368f175ef 569 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 408 427 - T 12-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 VAPA_1c51610 1d713122eede790bba77e69368f175ef 569 SUPERFAMILY SSF47203 291 451 4.35E-36 T 12-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 VAPA_1c51610 1d713122eede790bba77e69368f175ef 569 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 293 449 5.5E-29 T 12-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 VAPA_1c51610 1d713122eede790bba77e69368f175ef 569 SUPERFAMILY SSF56645 100 302 3.14E-42 T 12-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 VAPA_1c51610 1d713122eede790bba77e69368f175ef 569 Gene3D G3DSA:2.40.110.20 140 293 1.9E-47 T 12-10-2018 VAPA_1c51610 1d713122eede790bba77e69368f175ef 569 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 183 282 1.9E-16 T 12-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 VAPA_1c33210 9acf60d6f80bc0e74fe3776256413ca6 142 Gene3D G3DSA:3.30.720.110 71 125 1.3E-26 T 12-10-2018 VAPA_1c33210 9acf60d6f80bc0e74fe3776256413ca6 142 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 9 121 2.2E-9 T 12-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain VAPA_1c33210 9acf60d6f80bc0e74fe3776256413ca6 142 Gene3D G3DSA:3.30.720.120 2 55 4.9E-27 T 12-10-2018 VAPA_1c33210 9acf60d6f80bc0e74fe3776256413ca6 142 SUPERFAMILY SSF54593 6 123 7.25E-25 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase VAPA_1c27600 75710838e1df212998dc290d0e8edd45 232 SMART SM00248 135 164 20.0 T 12-10-2018 IPR002110 Ankyrin repeat GO:0005515 VAPA_1c27600 75710838e1df212998dc290d0e8edd45 232 SMART SM00248 68 97 9.8E-4 T 12-10-2018 IPR002110 Ankyrin repeat GO:0005515 VAPA_1c27600 75710838e1df212998dc290d0e8edd45 232 SMART SM00248 168 202 4400.0 T 12-10-2018 IPR002110 Ankyrin repeat GO:0005515 VAPA_1c27600 75710838e1df212998dc290d0e8edd45 232 SMART SM00248 101 130 2600.0 T 12-10-2018 IPR002110 Ankyrin repeat GO:0005515 VAPA_1c27600 75710838e1df212998dc290d0e8edd45 232 SMART SM00248 35 64 500.0 T 12-10-2018 IPR002110 Ankyrin repeat GO:0005515 VAPA_1c27600 75710838e1df212998dc290d0e8edd45 232 Pfam PF12796 Ankyrin repeats (3 copies) 40 126 1.9E-8 T 12-10-2018 IPR020683 Ankyrin repeat-containing domain VAPA_1c27600 75710838e1df212998dc290d0e8edd45 232 Gene3D G3DSA:1.25.40.20 37 228 2.7E-39 T 12-10-2018 IPR036770 Ankyrin repeat-containing domain superfamily VAPA_1c27600 75710838e1df212998dc290d0e8edd45 232 SUPERFAMILY SSF48403 39 227 3.79E-37 T 12-10-2018 IPR036770 Ankyrin repeat-containing domain superfamily VAPA_1c00470 99d5f446ee281f13e62175b33893109e 304 SUPERFAMILY SSF52540 1 260 4.29E-62 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c00470 99d5f446ee281f13e62175b33893109e 304 Pfam PF13614 AAA domain 3 183 4.8E-61 T 12-10-2018 IPR025669 AAA domain VAPA_1c00470 99d5f446ee281f13e62175b33893109e 304 Gene3D G3DSA:3.40.50.300 1 262 2.5E-75 T 12-10-2018 VAPA_2c02560 b96c43608d74df3337e9aec798f41c7a 502 Gene3D G3DSA:3.40.309.10 276 469 1.6E-180 T 12-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 VAPA_2c02560 b96c43608d74df3337e9aec798f41c7a 502 Gene3D G3DSA:3.40.605.10 32 492 1.6E-180 T 12-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 VAPA_2c02560 b96c43608d74df3337e9aec798f41c7a 502 Pfam PF00171 Aldehyde dehydrogenase family 31 496 2.6E-172 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 VAPA_2c02560 b96c43608d74df3337e9aec798f41c7a 502 SUPERFAMILY SSF53720 17 499 9.29E-170 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 VAPA_2c02560 b96c43608d74df3337e9aec798f41c7a 502 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 269 276 - T 12-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 VAPA_2c00280 ba4b586309a9b9082b1afcc753da6b59 252 SMART SM00382 30 222 1.2E-4 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_2c00280 ba4b586309a9b9082b1afcc753da6b59 252 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 222 244 9.9E-9 T 12-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal VAPA_2c00280 ba4b586309a9b9082b1afcc753da6b59 252 SUPERFAMILY SSF52540 5 244 7.14E-55 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_2c00280 ba4b586309a9b9082b1afcc753da6b59 252 Gene3D G3DSA:3.40.50.300 4 248 2.7E-54 T 12-10-2018 VAPA_2c00280 ba4b586309a9b9082b1afcc753da6b59 252 Pfam PF00005 ABC transporter 22 175 8.5E-27 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_2c00280 ba4b586309a9b9082b1afcc753da6b59 252 TIGRFAM TIGR03411 urea_trans_UrtD: urea ABC transporter, ATP-binding protein UrtD 5 244 1.2E-97 T 12-10-2018 IPR017781 ABC transporter, urea, ATP-binding protein, UrtD VAPA_1c48140 64d3322a38b80897560312688c860191 446 Pfam PF06742 Protein of unknown function (DUF1214) 314 424 8.2E-37 T 12-10-2018 IPR010621 Domain of unknown function DUF1214 VAPA_1c48140 64d3322a38b80897560312688c860191 446 SUPERFAMILY SSF160935 6 439 5.23E-113 T 12-10-2018 VAPA_1c48140 64d3322a38b80897560312688c860191 446 Gene3D G3DSA:2.60.120.1600 316 445 3.5E-41 T 12-10-2018 VAPA_1c48140 64d3322a38b80897560312688c860191 446 Gene3D G3DSA:1.10.3360.10 14 261 6.4E-12 T 12-10-2018 IPR023289 VPA0735-like domain superfamily VAPA_1c48140 64d3322a38b80897560312688c860191 446 Pfam PF06863 Protein of unknown function (DUF1254) 51 182 4.6E-44 T 12-10-2018 IPR010679 Domain of unknown function DUF1254 VAPA_1c48140 64d3322a38b80897560312688c860191 446 Gene3D G3DSA:2.60.40.1610 43 202 6.4E-12 T 12-10-2018 IPR037050 Domain of unknown function DUF1254 superfamily VAPA_1c37440 a657ccca32d52d58113d7b963fc19a84 139 Gene3D G3DSA:3.10.129.10 1 130 5.5E-28 T 12-10-2018 VAPA_1c37440 a657ccca32d52d58113d7b963fc19a84 139 SUPERFAMILY SSF54637 7 134 1.05E-23 T 12-10-2018 IPR029069 HotDog domain superfamily VAPA_1c37440 a657ccca32d52d58113d7b963fc19a84 139 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 16 105 1.5E-10 T 12-10-2018 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-77289 VAPA_1c37440 a657ccca32d52d58113d7b963fc19a84 139 Pfam PF03061 Thioesterase superfamily 46 115 6.5E-9 T 12-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 VAPA_1c50580 a70d25790b0481ea8270e913d6cc9f66 87 PRINTS PR00124 ATP synthase C subunit signature 10 29 5.8E-6 T 12-10-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 VAPA_1c50580 a70d25790b0481ea8270e913d6cc9f66 87 PRINTS PR00124 ATP synthase C subunit signature 31 46 5.8E-6 T 12-10-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 VAPA_1c50580 a70d25790b0481ea8270e913d6cc9f66 87 Pfam PF00137 ATP synthase subunit C 9 70 7.8E-12 T 12-10-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 VAPA_1c50580 a70d25790b0481ea8270e913d6cc9f66 87 TIGRFAM TIGR01260 ATP_synt_c: ATP synthase F0, C subunit 19 73 2.2E-22 T 12-10-2018 IPR005953 ATP synthase, F0 complex, subunit C, bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 VAPA_1c50580 a70d25790b0481ea8270e913d6cc9f66 87 Hamap MF_01396 ATP synthase subunit c [atpH]. 8 73 14.092 T 12-10-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 VAPA_1c50580 a70d25790b0481ea8270e913d6cc9f66 87 SUPERFAMILY SSF81333 4 76 2.09E-18 T 12-10-2018 IPR035921 F/V-ATP synthase subunit C superfamily VAPA_1c50580 a70d25790b0481ea8270e913d6cc9f66 87 Gene3D G3DSA:1.20.20.10 2 75 2.8E-27 T 12-10-2018 IPR038662 F1F0 ATP synthase subunit C superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 VAPA_1c50580 a70d25790b0481ea8270e913d6cc9f66 87 ProSitePatterns PS00605 ATP synthase c subunit signature. 38 59 - T 12-10-2018 IPR020537 ATP synthase, F0 complex, subunit C, DCCD-binding site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 VAPA_1c14170 33a0e49646b129aace8a94c793258217 483 SUPERFAMILY SSF53383 101 470 6.18E-92 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase VAPA_1c14170 33a0e49646b129aace8a94c793258217 483 Gene3D G3DSA:1.10.10.10 5 73 4.3E-14 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c14170 33a0e49646b129aace8a94c793258217 483 Pfam PF00155 Aminotransferase class I and II 139 451 7.2E-35 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 VAPA_1c14170 33a0e49646b129aace8a94c793258217 483 Gene3D G3DSA:3.40.640.10 146 364 1.2E-104 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 VAPA_1c14170 33a0e49646b129aace8a94c793258217 483 Gene3D G3DSA:3.90.1150.10 101 468 1.2E-104 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 VAPA_1c14170 33a0e49646b129aace8a94c793258217 483 SUPERFAMILY SSF46785 5 80 1.09E-13 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c14170 33a0e49646b129aace8a94c793258217 483 Pfam PF00392 Bacterial regulatory proteins, gntR family 20 71 1.2E-7 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_1c14170 33a0e49646b129aace8a94c793258217 483 SMART SM00345 12 71 2.6E-7 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_1c48130 8fde7ed31c424c9465b492218ab6d0ef 462 Pfam PF06863 Protein of unknown function (DUF1254) 63 197 3.4E-39 T 12-10-2018 IPR010679 Domain of unknown function DUF1254 VAPA_1c48130 8fde7ed31c424c9465b492218ab6d0ef 462 Pfam PF06742 Protein of unknown function (DUF1214) 340 447 9.3E-35 T 12-10-2018 IPR010621 Domain of unknown function DUF1214 VAPA_1c48130 8fde7ed31c424c9465b492218ab6d0ef 462 Gene3D G3DSA:1.10.3360.10 224 267 4.0E-9 T 12-10-2018 IPR023289 VPA0735-like domain superfamily VAPA_1c48130 8fde7ed31c424c9465b492218ab6d0ef 462 Gene3D G3DSA:2.60.40.1610 73 223 4.0E-9 T 12-10-2018 IPR037050 Domain of unknown function DUF1254 superfamily VAPA_1c48130 8fde7ed31c424c9465b492218ab6d0ef 462 Gene3D G3DSA:2.60.120.600 313 461 1.1E-36 T 12-10-2018 IPR037049 Domain of unknown function DUF1214, C-terminal domain superfamily VAPA_1c48130 8fde7ed31c424c9465b492218ab6d0ef 462 SUPERFAMILY SSF160935 10 458 7.85E-99 T 12-10-2018 VAPA_1c41620 71e310f60c96c517afa9f68dda85998d 490 SUPERFAMILY SSF103473 16 205 9.81E-43 T 12-10-2018 IPR036259 MFS transporter superfamily VAPA_1c41620 71e310f60c96c517afa9f68dda85998d 490 Gene3D G3DSA:1.20.1250.20 287 479 1.2E-17 T 12-10-2018 VAPA_1c41620 71e310f60c96c517afa9f68dda85998d 490 Gene3D G3DSA:1.20.1720.10 27 240 8.7E-46 T 12-10-2018 VAPA_1c41620 71e310f60c96c517afa9f68dda85998d 490 Pfam PF07690 Major Facilitator Superfamily 31 436 2.8E-45 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 VAPA_1c41620 71e310f60c96c517afa9f68dda85998d 490 SUPERFAMILY SSF103473 232 482 3.92E-21 T 12-10-2018 IPR036259 MFS transporter superfamily VAPA_1c41620 71e310f60c96c517afa9f68dda85998d 490 PRINTS PR01036 Tetracycline resistance protein TetB signature 150 174 2.8E-6 T 12-10-2018 VAPA_1c41620 71e310f60c96c517afa9f68dda85998d 490 PRINTS PR01036 Tetracycline resistance protein TetB signature 29 53 2.8E-6 T 12-10-2018 VAPA_1c41620 71e310f60c96c517afa9f68dda85998d 490 PRINTS PR01036 Tetracycline resistance protein TetB signature 120 140 2.8E-6 T 12-10-2018 VAPA_2c07130 a83852ce32a5adf00d2e3e26adf6e69f 357 Gene3D G3DSA:3.40.190.170 36 350 1.1E-66 T 12-10-2018 IPR038404 TRAP transporter solute receptor DctP superfamily VAPA_2c07130 a83852ce32a5adf00d2e3e26adf6e69f 357 SUPERFAMILY SSF53850 57 271 5.25E-9 T 12-10-2018 VAPA_2c07130 a83852ce32a5adf00d2e3e26adf6e69f 357 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 40 284 3.7E-33 T 12-10-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0030288|GO:0055085 VAPA_1c44270 e22dd2117ecfe832a8bc0fc1e05bb4a6 1136 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 678 1130 9.2E-87 T 12-10-2018 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0016020|GO:0022857|GO:0055085 VAPA_1c44270 e22dd2117ecfe832a8bc0fc1e05bb4a6 1136 SUPERFAMILY SSF56954 662 1133 1.02E-90 T 12-10-2018 VAPA_1c44270 e22dd2117ecfe832a8bc0fc1e05bb4a6 1136 SUPERFAMILY SSF53448 114 383 7.03E-39 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases VAPA_1c44270 e22dd2117ecfe832a8bc0fc1e05bb4a6 1136 Gene3D G3DSA:3.90.550.10 107 327 8.9E-67 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases VAPA_1c44270 e22dd2117ecfe832a8bc0fc1e05bb4a6 1136 Gene3D G3DSA:1.20.1600.10 715 1131 1.1E-105 T 12-10-2018 VAPA_1c44270 e22dd2117ecfe832a8bc0fc1e05bb4a6 1136 Pfam PF02321 Outer membrane efflux protein 727 919 3.8E-15 T 12-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 VAPA_1c44270 e22dd2117ecfe832a8bc0fc1e05bb4a6 1136 Pfam PF02321 Outer membrane efflux protein 946 1128 2.1E-26 T 12-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 VAPA_1c44270 e22dd2117ecfe832a8bc0fc1e05bb4a6 1136 Pfam PF00535 Glycosyl transferase family 2 119 287 2.2E-22 T 12-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 VAPA_1c44270 e22dd2117ecfe832a8bc0fc1e05bb4a6 1136 Pfam PF07238 PilZ domain 538 628 9.5E-8 T 12-10-2018 IPR009875 PilZ domain GO:0035438 VAPA_1c44270 e22dd2117ecfe832a8bc0fc1e05bb4a6 1136 Gene3D G3DSA:2.20.200.10 761 1019 1.1E-105 T 12-10-2018 VAPA_1c44270 e22dd2117ecfe832a8bc0fc1e05bb4a6 1136 PRINTS PR01439 Cellulose synthase subunit A signature 398 417 2.0E-5 T 12-10-2018 IPR003919 Cellulose synthase, subunit A GO:0006011|GO:0016020|GO:0016759|GO:0035438 KEGG: 00500+2.4.1.12|MetaCyc: PWY-1001 VAPA_1c44270 e22dd2117ecfe832a8bc0fc1e05bb4a6 1136 PRINTS PR01439 Cellulose synthase subunit A signature 508 529 2.0E-5 T 12-10-2018 IPR003919 Cellulose synthase, subunit A GO:0006011|GO:0016020|GO:0016759|GO:0035438 KEGG: 00500+2.4.1.12|MetaCyc: PWY-1001 VAPA_1c44270 e22dd2117ecfe832a8bc0fc1e05bb4a6 1136 PRINTS PR01439 Cellulose synthase subunit A signature 35 55 2.0E-5 T 12-10-2018 IPR003919 Cellulose synthase, subunit A GO:0006011|GO:0016020|GO:0016759|GO:0035438 KEGG: 00500+2.4.1.12|MetaCyc: PWY-1001 VAPA_1c39400 94ac1536e3208cce8b7fdd35add324ad 583 SUPERFAMILY SSF53300 376 569 6.78E-12 T 12-10-2018 IPR036465 von Willebrand factor A-like domain superfamily VAPA_1c39400 94ac1536e3208cce8b7fdd35add324ad 583 PIRSF PIRSF031715 248 583 3.2E-86 T 12-10-2018 IPR006538 Cobalt chelatase, CobT subunit GO:0009236 KEGG: 00860+6.6.1.2|MetaCyc: PWY-7376 VAPA_1c39400 94ac1536e3208cce8b7fdd35add324ad 583 PIRSF PIRSF031715 10 245 2.2E-21 T 12-10-2018 IPR006538 Cobalt chelatase, CobT subunit GO:0009236 KEGG: 00860+6.6.1.2|MetaCyc: PWY-7376 VAPA_1c39400 94ac1536e3208cce8b7fdd35add324ad 583 Gene3D G3DSA:3.40.50.410 374 575 1.5E-6 T 12-10-2018 IPR036465 von Willebrand factor A-like domain superfamily VAPA_1c39400 94ac1536e3208cce8b7fdd35add324ad 583 Pfam PF11775 Cobalamin biosynthesis protein CobT VWA domain 363 577 5.7E-53 T 12-10-2018 IPR025861 Cobalamin biosynthesis protein CobT VWA domain KEGG: 00860+6.6.1.2|MetaCyc: PWY-7376 VAPA_1c39400 94ac1536e3208cce8b7fdd35add324ad 583 Pfam PF06213 Cobalamin biosynthesis protein CobT 29 237 7.8E-26 T 12-10-2018 IPR006538 Cobalt chelatase, CobT subunit GO:0009236 KEGG: 00860+6.6.1.2|MetaCyc: PWY-7376 VAPA_1c53260 389614f5064ec9503697e70a8e133d59 453 SUPERFAMILY SSF56176 7 216 1.84E-38 T 12-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 VAPA_1c53260 389614f5064ec9503697e70a8e133d59 453 Gene3D G3DSA:3.30.465.40 20 231 4.3E-29 T 12-10-2018 VAPA_1c53260 389614f5064ec9503697e70a8e133d59 453 Pfam PF01565 FAD binding domain 49 179 1.2E-26 T 12-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 VAPA_1c11350 85db038324ebb0ead85927cee5222a3e 146 PRINTS PR00813 Bacterial general secretion pathway protein G signature 15 40 4.9E-17 T 12-10-2018 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 VAPA_1c11350 85db038324ebb0ead85927cee5222a3e 146 PRINTS PR00813 Bacterial general secretion pathway protein G signature 51 69 4.9E-17 T 12-10-2018 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 VAPA_1c11350 85db038324ebb0ead85927cee5222a3e 146 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 14 34 - T 12-10-2018 IPR012902 Prokaryotic N-terminal methylation site VAPA_1c11350 85db038324ebb0ead85927cee5222a3e 146 Pfam PF07963 Prokaryotic N-terminal methylation motif 11 35 1.1E-9 T 12-10-2018 IPR012902 Prokaryotic N-terminal methylation site VAPA_1c11350 85db038324ebb0ead85927cee5222a3e 146 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 13 35 4.0E-10 T 12-10-2018 IPR012902 Prokaryotic N-terminal methylation site VAPA_1c11350 85db038324ebb0ead85927cee5222a3e 146 Gene3D G3DSA:3.30.700.10 38 145 4.1E-37 T 12-10-2018 VAPA_1c11350 85db038324ebb0ead85927cee5222a3e 146 SUPERFAMILY SSF54523 42 145 4.97E-35 T 12-10-2018 VAPA_1c11350 85db038324ebb0ead85927cee5222a3e 146 Pfam PF08334 Type II secretion system (T2SS), protein G 38 145 3.7E-40 T 12-10-2018 IPR013545 Type II secretion system protein G VAPA_1c11350 85db038324ebb0ead85927cee5222a3e 146 TIGRFAM TIGR01710 typeII_sec_gspG: type II secretion system protein G 14 146 1.2E-53 T 12-10-2018 IPR010054 General secretion pathway protein G GO:0008565|GO:0015627|GO:0015628 VAPA_1c38350 2ce3595026985019dd90ea913a38222a 231 SUPERFAMILY SSF110857 15 129 1.41E-11 T 12-10-2018 IPR036568 Gamma-glutamyl cyclotransferase-like superfamily VAPA_1c38350 2ce3595026985019dd90ea913a38222a 231 Gene3D G3DSA:3.10.490.10 10 197 1.3E-9 T 12-10-2018 VAPA_1c38350 2ce3595026985019dd90ea913a38222a 231 Pfam PF04752 ChaC-like protein 15 179 1.1E-35 T 12-10-2018 IPR006840 Glutathione-specific gamma-glutamylcyclotransferase GO:0003839|GO:0006751 KEGG: 00480+4.3.2.7|MetaCyc: PWY-7942|Reactome: R-HSA-174403 VAPA_1c27450 6bedb83a6c5f8c3045c8865b9e097d3d 237 Gene3D G3DSA:3.40.470.10 1 205 3.8E-56 T 12-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 VAPA_1c27450 6bedb83a6c5f8c3045c8865b9e097d3d 237 TIGRFAM TIGR00758 UDG_fam4: uracil-DNA glycosylase, family 4 21 188 1.1E-39 T 12-10-2018 IPR005273 Uracil-DNA glycosylase family 4 VAPA_1c27450 6bedb83a6c5f8c3045c8865b9e097d3d 237 TIGRFAM TIGR03914 UDG_fam_dom: uracil-DNA glycosylase family domain 5 196 1.6E-78 T 12-10-2018 IPR005273 Uracil-DNA glycosylase family 4 VAPA_1c27450 6bedb83a6c5f8c3045c8865b9e097d3d 237 SMART SM00986 35 191 5.6E-33 T 12-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 VAPA_1c27450 6bedb83a6c5f8c3045c8865b9e097d3d 237 Pfam PF03167 Uracil DNA glycosylase superfamily 35 190 1.1E-38 T 12-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 VAPA_1c27450 6bedb83a6c5f8c3045c8865b9e097d3d 237 SUPERFAMILY SSF52141 13 203 3.92E-49 T 12-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 VAPA_1c27450 6bedb83a6c5f8c3045c8865b9e097d3d 237 SMART SM00987 35 191 5.6E-33 T 12-10-2018 VAPA_1c49930 3e9850add45cbccccf27fa612499ca58 295 Gene3D G3DSA:1.10.10.10 1 90 7.9E-29 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c49930 3e9850add45cbccccf27fa612499ca58 295 Gene3D G3DSA:3.40.190.10 95 261 1.1E-40 T 12-10-2018 VAPA_1c49930 3e9850add45cbccccf27fa612499ca58 295 SUPERFAMILY SSF46785 1 111 1.04E-25 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c49930 3e9850add45cbccccf27fa612499ca58 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 1.8E-9 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c49930 3e9850add45cbccccf27fa612499ca58 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 1.8E-9 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c49930 3e9850add45cbccccf27fa612499ca58 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 1.8E-9 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c49930 3e9850add45cbccccf27fa612499ca58 295 Pfam PF03466 LysR substrate binding domain 92 282 9.4E-25 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_1c49930 3e9850add45cbccccf27fa612499ca58 295 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 62 2.0E-23 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c49930 3e9850add45cbccccf27fa612499ca58 295 Gene3D G3DSA:3.40.190.10 161 255 1.1E-40 T 12-10-2018 VAPA_1c49930 3e9850add45cbccccf27fa612499ca58 295 SUPERFAMILY SSF53850 92 284 4.42E-24 T 12-10-2018 VAPA_1c02050 3b9d97a1c412be5d52afacff1febe691 308 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 64 1.4E-18 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c02050 3b9d97a1c412be5d52afacff1febe691 308 Gene3D G3DSA:1.10.10.10 2 87 2.1E-19 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c02050 3b9d97a1c412be5d52afacff1febe691 308 SUPERFAMILY SSF53850 88 293 7.42E-27 T 12-10-2018 VAPA_1c02050 3b9d97a1c412be5d52afacff1febe691 308 Gene3D G3DSA:3.40.190.290 94 300 3.7E-26 T 12-10-2018 VAPA_1c02050 3b9d97a1c412be5d52afacff1febe691 308 SUPERFAMILY SSF46785 6 85 3.26E-17 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c02050 3b9d97a1c412be5d52afacff1febe691 308 Pfam PF03466 LysR substrate binding domain 89 293 2.6E-22 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_1c15400 8e88c7c3d9076d89ae8f0142ca260ccf 286 Gene3D G3DSA:1.20.58.480 27 286 5.1E-98 T 12-10-2018 VAPA_1c15400 8e88c7c3d9076d89ae8f0142ca260ccf 286 SUPERFAMILY SSF140959 29 285 1.83E-104 T 12-10-2018 IPR037217 Tryptophan/Indoleamine 2,3-dioxygenase-like GO:0019441|GO:0020037|GO:0046872 KEGG: 00380+1.13.11.11|Reactome: R-HSA-71240 VAPA_1c15400 8e88c7c3d9076d89ae8f0142ca260ccf 286 Hamap MF_01972 Tryptophan 2,3-dioxygenase [kynA]. 23 286 40.999 T 12-10-2018 IPR004981 Tryptophan 2,3-dioxygenase GO:0004833|GO:0019441|GO:0020037 KEGG: 00380+1.13.11.11|Reactome: R-HSA-71240 VAPA_1c15400 8e88c7c3d9076d89ae8f0142ca260ccf 286 Pfam PF03301 Tryptophan 2,3-dioxygenase 18 284 3.2E-70 T 12-10-2018 IPR004981 Tryptophan 2,3-dioxygenase GO:0004833|GO:0019441|GO:0020037 KEGG: 00380+1.13.11.11|Reactome: R-HSA-71240 VAPA_1c15400 8e88c7c3d9076d89ae8f0142ca260ccf 286 TIGRFAM TIGR03036 trp_2_3_diox: tryptophan 2,3-dioxygenase 23 286 5.4E-132 T 12-10-2018 IPR017485 Tryptophan 2,3-dioxygenase, bacterial GO:0004833|GO:0019441 KEGG: 00380+1.13.11.11 VAPA_2c06810 345a525fac38a5025576a2ec4b0b2abd 525 ProSitePatterns PS00455 Putative AMP-binding domain signature. 173 184 - T 12-10-2018 IPR020845 AMP-binding, conserved site VAPA_2c06810 345a525fac38a5025576a2ec4b0b2abd 525 Gene3D G3DSA:3.40.50.12780 14 411 3.8E-84 T 12-10-2018 VAPA_2c06810 345a525fac38a5025576a2ec4b0b2abd 525 Pfam PF13193 AMP-binding enzyme C-terminal domain 425 497 2.0E-13 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain VAPA_2c06810 345a525fac38a5025576a2ec4b0b2abd 525 Gene3D G3DSA:3.30.300.30 412 511 1.3E-22 T 12-10-2018 VAPA_2c06810 345a525fac38a5025576a2ec4b0b2abd 525 Pfam PF00501 AMP-binding enzyme 26 415 1.3E-71 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 VAPA_2c06810 345a525fac38a5025576a2ec4b0b2abd 525 SUPERFAMILY SSF56801 19 511 1.31E-118 T 12-10-2018 VAPA_2c03620 23f8e9ac9e791e81b80e7c808e6e8d17 470 SUPERFAMILY SSF53098 17 397 6.75E-29 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily VAPA_2c03620 23f8e9ac9e791e81b80e7c808e6e8d17 470 Pfam PF13546 DDE superfamily endonuclease 14 287 1.6E-94 T 12-10-2018 IPR038721 Transposase IS701-like, DDE domain VAPA_1c27000 5bbabc4475408d3a97f6112606ca6059 269 PIRSF PIRSF005902 1 267 3.6E-77 T 12-10-2018 IPR001130 TatD family GO:0016788 VAPA_1c27000 5bbabc4475408d3a97f6112606ca6059 269 SUPERFAMILY SSF51556 2 264 5.0E-83 T 12-10-2018 IPR032466 Metal-dependent hydrolase VAPA_1c27000 5bbabc4475408d3a97f6112606ca6059 269 Gene3D G3DSA:3.20.20.140 1 268 2.9E-87 T 12-10-2018 VAPA_1c27000 5bbabc4475408d3a97f6112606ca6059 269 Pfam PF01026 TatD related DNase 3 264 4.6E-76 T 12-10-2018 IPR001130 TatD family GO:0016788 VAPA_1c27000 5bbabc4475408d3a97f6112606ca6059 269 TIGRFAM TIGR00010 TIGR00010: hydrolase, TatD family 3 264 2.8E-82 T 12-10-2018 IPR015991 Uncharacterised hydrolase TatD-type GO:0004536 VAPA_1c51720 d6c0a4c9711c4124d51ca99f536dde1a 469 PRINTS PR00344 Bacterial sensor protein C-terminal signature 444 457 3.5E-10 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c51720 d6c0a4c9711c4124d51ca99f536dde1a 469 PRINTS PR00344 Bacterial sensor protein C-terminal signature 415 433 3.5E-10 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c51720 d6c0a4c9711c4124d51ca99f536dde1a 469 PRINTS PR00344 Bacterial sensor protein C-terminal signature 383 397 3.5E-10 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c51720 d6c0a4c9711c4124d51ca99f536dde1a 469 PRINTS PR00344 Bacterial sensor protein C-terminal signature 401 411 3.5E-10 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c51720 d6c0a4c9711c4124d51ca99f536dde1a 469 Gene3D G3DSA:3.30.565.10 305 462 4.4E-31 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_1c51720 d6c0a4c9711c4124d51ca99f536dde1a 469 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 350 456 1.1E-16 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase VAPA_1c51720 d6c0a4c9711c4124d51ca99f536dde1a 469 SUPERFAMILY SSF47384 219 300 6.67E-16 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 VAPA_1c51720 d6c0a4c9711c4124d51ca99f536dde1a 469 Gene3D G3DSA:1.10.287.130 186 301 2.2E-22 T 12-10-2018 VAPA_1c51720 d6c0a4c9711c4124d51ca99f536dde1a 469 SMART SM00387 346 460 2.5E-30 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase VAPA_1c51720 d6c0a4c9711c4124d51ca99f536dde1a 469 SUPERFAMILY SSF55874 290 458 1.24E-36 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_1c51720 d6c0a4c9711c4124d51ca99f536dde1a 469 SMART SM00388 236 301 3.6E-13 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 VAPA_1c51720 d6c0a4c9711c4124d51ca99f536dde1a 469 Pfam PF00512 His Kinase A (phospho-acceptor) domain 237 300 1.3E-12 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 VAPA_1c18850 93e7393f560869eda71359d4eb159182 257 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 47 254 1.1E-51 T 12-10-2018 VAPA_1c18850 93e7393f560869eda71359d4eb159182 257 Gene3D G3DSA:3.40.50.150 32 256 4.6E-68 T 12-10-2018 VAPA_1c18850 93e7393f560869eda71359d4eb159182 257 TIGRFAM TIGR00080 pimt: protein-L-isoaspartate O-methyltransferase 43 255 1.7E-54 T 12-10-2018 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 VAPA_1c18850 93e7393f560869eda71359d4eb159182 257 SUPERFAMILY SSF53335 53 255 1.8E-34 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase VAPA_1c10340 c51da2b79110b3a0d1d2a10326bffb6f 258 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 82 95 - T 12-10-2018 IPR020583 Inositol monophosphatase, metal-binding site VAPA_1c10340 c51da2b79110b3a0d1d2a10326bffb6f 258 TIGRFAM TIGR02067 his_9_HisN: histidinol-phosphatase 9 256 2.5E-85 T 12-10-2018 IPR011809 Histidinol-phosphate phosphatase, putative, inositol monophosphatase GO:0004401 KEGG: 00340+3.1.3.15 VAPA_1c10340 c51da2b79110b3a0d1d2a10326bffb6f 258 Pfam PF00459 Inositol monophosphatase family 9 254 5.7E-47 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 VAPA_1c10340 c51da2b79110b3a0d1d2a10326bffb6f 258 Gene3D G3DSA:3.40.190.80 142 257 4.7E-32 T 12-10-2018 VAPA_1c10340 c51da2b79110b3a0d1d2a10326bffb6f 258 PRINTS PR00377 Inositol monophosphatase superfamily signature 205 229 1.6E-18 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 VAPA_1c10340 c51da2b79110b3a0d1d2a10326bffb6f 258 PRINTS PR00377 Inositol monophosphatase superfamily signature 40 60 1.6E-18 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 VAPA_1c10340 c51da2b79110b3a0d1d2a10326bffb6f 258 PRINTS PR00377 Inositol monophosphatase superfamily signature 82 98 1.6E-18 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 VAPA_1c10340 c51da2b79110b3a0d1d2a10326bffb6f 258 PRINTS PR00377 Inositol monophosphatase superfamily signature 131 154 1.6E-18 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 VAPA_1c10340 c51da2b79110b3a0d1d2a10326bffb6f 258 PRINTS PR00377 Inositol monophosphatase superfamily signature 174 195 1.6E-18 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 VAPA_1c10340 c51da2b79110b3a0d1d2a10326bffb6f 258 SUPERFAMILY SSF56655 7 256 8.77E-71 T 12-10-2018 VAPA_1c10340 c51da2b79110b3a0d1d2a10326bffb6f 258 Gene3D G3DSA:3.30.540.10 3 140 1.2E-38 T 12-10-2018 VAPA_1c27560 c3f5ea7a77c32912542ff1c50d16bbfe 317 PIRSF PIRSF028757 2 303 9.0E-62 T 12-10-2018 IPR003507 Peptidase family S66 VAPA_1c27560 c3f5ea7a77c32912542ff1c50d16bbfe 317 Pfam PF02016 LD-carboxypeptidase 5 291 2.8E-67 T 12-10-2018 IPR003507 Peptidase family S66 VAPA_1c27560 c3f5ea7a77c32912542ff1c50d16bbfe 317 Gene3D G3DSA:3.40.50.10740 2 152 1.9E-29 T 12-10-2018 IPR027478 Murein tetrapeptide carboxypeptidase, N-terminal VAPA_1c27560 c3f5ea7a77c32912542ff1c50d16bbfe 317 SUPERFAMILY SSF52317 3 156 3.3E-30 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like VAPA_1c27560 c3f5ea7a77c32912542ff1c50d16bbfe 317 Gene3D G3DSA:3.50.30.60 167 298 4.2E-40 T 12-10-2018 IPR027461 LD-carboxypeptidase A, C-terminal domain superfamily VAPA_1c27560 c3f5ea7a77c32912542ff1c50d16bbfe 317 SUPERFAMILY SSF141986 171 295 2.48E-38 T 12-10-2018 IPR027461 LD-carboxypeptidase A, C-terminal domain superfamily VAPA_1c52500 5b6fc78d843ab12ca0964aab746df0e1 179 Gene3D G3DSA:3.30.1440.10 1 179 1.0E-79 T 12-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VAPA_1c52500 5b6fc78d843ab12ca0964aab746df0e1 179 Hamap MF_01333_B 50S ribosomal protein L5 [rplE]. 1 179 43.397 T 12-10-2018 IPR020930 Ribosomal protein L5, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 VAPA_1c52500 5b6fc78d843ab12ca0964aab746df0e1 179 ProSitePatterns PS00358 Ribosomal protein L5 signature. 57 73 - T 12-10-2018 IPR020929 Ribosomal protein L5, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VAPA_1c52500 5b6fc78d843ab12ca0964aab746df0e1 179 Pfam PF00281 Ribosomal protein L5 24 80 7.4E-29 T 12-10-2018 IPR031310 Ribosomal protein L5, N-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VAPA_1c52500 5b6fc78d843ab12ca0964aab746df0e1 179 PIRSF PIRSF002161 1 179 9.5E-66 T 12-10-2018 IPR002132 Ribosomal protein L5 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VAPA_1c52500 5b6fc78d843ab12ca0964aab746df0e1 179 SUPERFAMILY SSF55282 3 179 3.77E-78 T 12-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VAPA_1c52500 5b6fc78d843ab12ca0964aab746df0e1 179 Pfam PF00673 ribosomal L5P family C-terminus 84 177 2.4E-39 T 12-10-2018 IPR031309 Ribosomal protein L5, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VAPA_1c21710 e7af1be17ba38c11e81df31d819e2ca4 597 ProSitePatterns PS00211 ABC transporters family signature. 469 483 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_1c21710 e7af1be17ba38c11e81df31d819e2ca4 597 Pfam PF00664 ABC transporter transmembrane region 27 269 5.9E-12 T 12-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 VAPA_1c21710 e7af1be17ba38c11e81df31d819e2ca4 597 SUPERFAMILY SSF90123 20 324 2.62E-34 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 VAPA_1c21710 e7af1be17ba38c11e81df31d819e2ca4 597 SUPERFAMILY SSF52540 321 556 3.62E-58 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c21710 e7af1be17ba38c11e81df31d819e2ca4 597 TIGRFAM TIGR01842 type_I_sec_PrtD: type I secretion system ATPase 17 558 1.0E-189 T 12-10-2018 IPR010128 ATPase, type I secretion system, PrtD GO:0005524|GO:0008565|GO:0016021|GO:0030253|GO:0030256 VAPA_1c21710 e7af1be17ba38c11e81df31d819e2ca4 597 Pfam PF00005 ABC transporter 349 496 6.4E-28 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c21710 e7af1be17ba38c11e81df31d819e2ca4 597 Gene3D G3DSA:1.20.1560.10 13 315 4.0E-24 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 VAPA_1c21710 e7af1be17ba38c11e81df31d819e2ca4 597 SMART SM00382 358 544 1.4E-12 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c21710 e7af1be17ba38c11e81df31d819e2ca4 597 Gene3D G3DSA:3.40.50.300 320 566 2.8E-64 T 12-10-2018 VAPA_1c10250 cd60dc2dec97faae0ae7040d524c6cb0 1054 SUPERFAMILY SSF82693 136 324 1.18E-23 T 12-10-2018 VAPA_1c10250 cd60dc2dec97faae0ae7040d524c6cb0 1054 SUPERFAMILY SSF82714 720 804 2.88E-15 T 12-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains VAPA_1c10250 cd60dc2dec97faae0ae7040d524c6cb0 1054 Gene3D G3DSA:1.20.1640.10 516 1021 1.5E-297 T 12-10-2018 VAPA_1c10250 cd60dc2dec97faae0ae7040d524c6cb0 1054 Gene3D G3DSA:3.30.70.1430 570 664 1.5E-297 T 12-10-2018 VAPA_1c10250 cd60dc2dec97faae0ae7040d524c6cb0 1054 SUPERFAMILY SSF82693 568 665 1.62E-14 T 12-10-2018 VAPA_1c10250 cd60dc2dec97faae0ae7040d524c6cb0 1054 Pfam PF00873 AcrB/AcrD/AcrF family 3 1024 0.0 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 VAPA_1c10250 cd60dc2dec97faae0ae7040d524c6cb0 1054 SUPERFAMILY SSF82866 801 1026 1.1E-44 T 12-10-2018 VAPA_1c10250 cd60dc2dec97faae0ae7040d524c6cb0 1054 Gene3D G3DSA:1.20.1640.10 10 515 1.5E-297 T 12-10-2018 VAPA_1c10250 cd60dc2dec97faae0ae7040d524c6cb0 1054 Gene3D G3DSA:3.30.2090.10 717 805 1.5E-297 T 12-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains VAPA_1c10250 cd60dc2dec97faae0ae7040d524c6cb0 1054 PRINTS PR00702 Acriflavin resistance protein family signature 357 378 2.8E-72 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 VAPA_1c10250 cd60dc2dec97faae0ae7040d524c6cb0 1054 PRINTS PR00702 Acriflavin resistance protein family signature 385 409 2.8E-72 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 VAPA_1c10250 cd60dc2dec97faae0ae7040d524c6cb0 1054 PRINTS PR00702 Acriflavin resistance protein family signature 622 636 2.8E-72 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 VAPA_1c10250 cd60dc2dec97faae0ae7040d524c6cb0 1054 PRINTS PR00702 Acriflavin resistance protein family signature 10 34 2.8E-72 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 VAPA_1c10250 cd60dc2dec97faae0ae7040d524c6cb0 1054 PRINTS PR00702 Acriflavin resistance protein family signature 463 486 2.8E-72 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 VAPA_1c10250 cd60dc2dec97faae0ae7040d524c6cb0 1054 PRINTS PR00702 Acriflavin resistance protein family signature 330 353 2.8E-72 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 VAPA_1c10250 cd60dc2dec97faae0ae7040d524c6cb0 1054 PRINTS PR00702 Acriflavin resistance protein family signature 438 461 2.8E-72 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 VAPA_1c10250 cd60dc2dec97faae0ae7040d524c6cb0 1054 PRINTS PR00702 Acriflavin resistance protein family signature 555 572 2.8E-72 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 VAPA_1c10250 cd60dc2dec97faae0ae7040d524c6cb0 1054 PRINTS PR00702 Acriflavin resistance protein family signature 38 56 2.8E-72 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 VAPA_1c10250 cd60dc2dec97faae0ae7040d524c6cb0 1054 SUPERFAMILY SSF82866 290 490 2.09E-46 T 12-10-2018 VAPA_1c10250 cd60dc2dec97faae0ae7040d524c6cb0 1054 Gene3D G3DSA:3.30.70.1440 665 863 1.5E-297 T 12-10-2018 VAPA_1c10250 cd60dc2dec97faae0ae7040d524c6cb0 1054 Gene3D G3DSA:3.30.70.1430 40 813 1.5E-297 T 12-10-2018 VAPA_1c10250 cd60dc2dec97faae0ae7040d524c6cb0 1054 Gene3D G3DSA:3.30.2090.10 179 269 1.5E-297 T 12-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains VAPA_1c10250 cd60dc2dec97faae0ae7040d524c6cb0 1054 Gene3D G3DSA:3.30.70.1320 135 326 1.5E-297 T 12-10-2018 VAPA_1c10250 cd60dc2dec97faae0ae7040d524c6cb0 1054 SUPERFAMILY SSF82714 185 266 1.01E-14 T 12-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains VAPA_1c10250 cd60dc2dec97faae0ae7040d524c6cb0 1054 SUPERFAMILY SSF82693 42 125 7.15E-21 T 12-10-2018 VAPA_1c18270 5cb42a4951303280c3bfe5c3b7a8dd00 602 SUPERFAMILY SSF52540 9 234 1.85E-58 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c18270 5cb42a4951303280c3bfe5c3b7a8dd00 602 SUPERFAMILY SSF52540 336 560 8.56E-63 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c18270 5cb42a4951303280c3bfe5c3b7a8dd00 602 Gene3D G3DSA:3.40.50.300 335 571 2.8E-67 T 12-10-2018 VAPA_1c18270 5cb42a4951303280c3bfe5c3b7a8dd00 602 Gene3D G3DSA:3.40.50.300 2 239 1.0E-63 T 12-10-2018 VAPA_1c18270 5cb42a4951303280c3bfe5c3b7a8dd00 602 SMART SM00382 366 547 4.8E-15 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c18270 5cb42a4951303280c3bfe5c3b7a8dd00 602 SMART SM00382 38 220 3.8E-12 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c18270 5cb42a4951303280c3bfe5c3b7a8dd00 602 Pfam PF00005 ABC transporter 360 501 1.4E-28 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c18270 5cb42a4951303280c3bfe5c3b7a8dd00 602 ProSitePatterns PS00211 ABC transporters family signature. 145 159 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_1c18270 5cb42a4951303280c3bfe5c3b7a8dd00 602 Pfam PF00005 ABC transporter 29 172 3.3E-30 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_2c06780 87003fd9f3755b96453c636cceb76bcc 319 Gene3D G3DSA:3.60.15.10 13 239 1.4E-42 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like VAPA_2c06780 87003fd9f3755b96453c636cceb76bcc 319 SUPERFAMILY SSF56281 17 311 8.4E-54 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like VAPA_2c06780 87003fd9f3755b96453c636cceb76bcc 319 SMART SM00849 35 222 9.0E-13 T 12-10-2018 IPR001279 Metallo-beta-lactamase VAPA_1c49120 42e9c7929023d6faff996e231dd48d30 424 Pfam PF07969 Amidohydrolase family 114 413 5.2E-9 T 12-10-2018 IPR013108 Amidohydrolase 3 VAPA_1c49120 42e9c7929023d6faff996e231dd48d30 424 SUPERFAMILY SSF51338 33 79 3.26E-5 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 VAPA_1c49120 42e9c7929023d6faff996e231dd48d30 424 Gene3D G3DSA:2.30.40.10 30 414 2.1E-73 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 VAPA_1c49120 42e9c7929023d6faff996e231dd48d30 424 SUPERFAMILY SSF51556 67 369 2.82E-64 T 12-10-2018 IPR032466 Metal-dependent hydrolase VAPA_1c49120 42e9c7929023d6faff996e231dd48d30 424 Gene3D G3DSA:3.20.20.140 68 372 2.1E-73 T 12-10-2018 VAPA_1c23300 72c93502970cc02795f2f026bdc7992a 367 Gene3D G3DSA:3.50.50.60 5 357 7.8E-137 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c23300 72c93502970cc02795f2f026bdc7992a 367 SUPERFAMILY SSF51905 5 365 7.77E-45 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c23300 72c93502970cc02795f2f026bdc7992a 367 Pfam PF01266 FAD dependent oxidoreductase 5 360 1.5E-63 T 12-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 VAPA_1c23300 72c93502970cc02795f2f026bdc7992a 367 Gene3D G3DSA:3.30.9.10 86 319 7.8E-137 T 12-10-2018 VAPA_1c24570 edc5f45edc5cedae5d685d77737b073f 464 Gene3D G3DSA:1.10.287.130 206 275 1.3E-24 T 12-10-2018 VAPA_1c24570 edc5f45edc5cedae5d685d77737b073f 464 Gene3D G3DSA:3.30.565.10 287 445 1.2E-36 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_1c24570 edc5f45edc5cedae5d685d77737b073f 464 PRINTS PR00344 Bacterial sensor protein C-terminal signature 361 375 2.2E-13 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c24570 edc5f45edc5cedae5d685d77737b073f 464 PRINTS PR00344 Bacterial sensor protein C-terminal signature 379 389 2.2E-13 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c24570 edc5f45edc5cedae5d685d77737b073f 464 PRINTS PR00344 Bacterial sensor protein C-terminal signature 420 433 2.2E-13 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c24570 edc5f45edc5cedae5d685d77737b073f 464 PRINTS PR00344 Bacterial sensor protein C-terminal signature 396 414 2.2E-13 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c24570 edc5f45edc5cedae5d685d77737b073f 464 Pfam PF00512 His Kinase A (phospho-acceptor) domain 209 274 2.8E-20 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 VAPA_1c24570 edc5f45edc5cedae5d685d77737b073f 464 SUPERFAMILY SSF55874 264 435 3.67E-40 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_1c24570 edc5f45edc5cedae5d685d77737b073f 464 Pfam PF11808 Domain of unknown function (DUF3329) 9 86 4.7E-8 T 12-10-2018 IPR021766 Phosphate regulon sensor protein PhoR GO:0000155|GO:0000160|GO:0004721 VAPA_1c24570 edc5f45edc5cedae5d685d77737b073f 464 SUPERFAMILY SSF55785 82 149 2.28E-9 T 12-10-2018 IPR035965 PAS domain superfamily VAPA_1c24570 edc5f45edc5cedae5d685d77737b073f 464 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 325 435 1.2E-21 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase VAPA_1c24570 edc5f45edc5cedae5d685d77737b073f 464 SMART SM00091 95 161 6.8E-6 T 12-10-2018 IPR000014 PAS domain VAPA_1c24570 edc5f45edc5cedae5d685d77737b073f 464 Pfam PF00989 PAS fold 96 146 2.0E-7 T 12-10-2018 IPR013767 PAS fold GO:0006355 VAPA_1c24570 edc5f45edc5cedae5d685d77737b073f 464 Gene3D G3DSA:3.30.450.20 79 205 2.7E-9 T 12-10-2018 VAPA_1c24570 edc5f45edc5cedae5d685d77737b073f 464 SMART SM00387 323 436 1.3E-36 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase VAPA_1c24570 edc5f45edc5cedae5d685d77737b073f 464 SUPERFAMILY SSF47384 196 273 1.53E-21 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 VAPA_1c24570 edc5f45edc5cedae5d685d77737b073f 464 SMART SM00388 209 275 1.6E-23 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 VAPA_1c24570 edc5f45edc5cedae5d685d77737b073f 464 TIGRFAM TIGR02966 phoR_proteo: phosphate regulon sensor kinase PhoR 93 432 1.7E-117 T 12-10-2018 IPR014310 Signal transduction histidine kinase, phosphate regulon sensor PhoR GO:0000155|GO:0000160|GO:0004673|GO:0016021 VAPA_1c49380 51241b502e1de42f19cf3d974a27fc99 579 SUPERFAMILY SSF56024 49 250 2.62E-35 T 12-10-2018 VAPA_1c49380 51241b502e1de42f19cf3d974a27fc99 579 Pfam PF13091 PLD-like domain 374 523 1.5E-21 T 12-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 VAPA_1c49380 51241b502e1de42f19cf3d974a27fc99 579 Pfam PF13091 PLD-like domain 80 232 2.2E-12 T 12-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 VAPA_1c49380 51241b502e1de42f19cf3d974a27fc99 579 Gene3D G3DSA:3.30.870.10 348 534 3.0E-33 T 12-10-2018 VAPA_1c49380 51241b502e1de42f19cf3d974a27fc99 579 Gene3D G3DSA:3.30.870.10 70 269 2.5E-35 T 12-10-2018 VAPA_1c49380 51241b502e1de42f19cf3d974a27fc99 579 SUPERFAMILY SSF56024 360 525 1.55E-30 T 12-10-2018 VAPA_1c49380 51241b502e1de42f19cf3d974a27fc99 579 SMART SM00155 471 498 0.22 T 12-10-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 VAPA_1c49380 51241b502e1de42f19cf3d974a27fc99 579 SMART SM00155 173 200 0.62 T 12-10-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 VAPA_1c37880 667d66ebc644db0fb0c6f6f2657c1386 217 Gene3D G3DSA:1.10.3720.10 4 213 3.5E-43 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c37880 667d66ebc644db0fb0c6f6f2657c1386 217 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 43 211 3.0E-12 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 VAPA_1c37880 667d66ebc644db0fb0c6f6f2657c1386 217 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 11 107 1.8E-26 T 12-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 VAPA_1c37880 667d66ebc644db0fb0c6f6f2657c1386 217 SUPERFAMILY SSF161098 13 198 1.09E-36 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c50500 7e2e8e65b8c6155e68032c7993513477 400 Gene3D G3DSA:3.30.420.40 202 375 3.1E-90 T 12-10-2018 VAPA_1c50500 7e2e8e65b8c6155e68032c7993513477 400 SUPERFAMILY SSF46785 10 67 5.11E-5 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c50500 7e2e8e65b8c6155e68032c7993513477 400 Gene3D G3DSA:3.30.420.40 84 384 3.1E-90 T 12-10-2018 VAPA_1c50500 7e2e8e65b8c6155e68032c7993513477 400 Gene3D G3DSA:1.10.10.10 13 72 5.8E-8 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c50500 7e2e8e65b8c6155e68032c7993513477 400 Pfam PF00480 ROK family 80 389 1.1E-56 T 12-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 VAPA_1c50500 7e2e8e65b8c6155e68032c7993513477 400 ProSitePatterns PS01125 ROK family signature. 212 239 - T 12-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 VAPA_1c50500 7e2e8e65b8c6155e68032c7993513477 400 SUPERFAMILY SSF53067 78 391 6.68E-60 T 12-10-2018 VAPA_1c40840 705daa94b5f05ae8e5fd2429c8646bf6 450 SUPERFAMILY SSF103473 32 442 2.49E-65 T 12-10-2018 IPR036259 MFS transporter superfamily VAPA_1c40840 705daa94b5f05ae8e5fd2429c8646bf6 450 Gene3D G3DSA:1.20.1250.20 35 445 1.3E-63 T 12-10-2018 VAPA_1c40840 705daa94b5f05ae8e5fd2429c8646bf6 450 Pfam PF00083 Sugar (and other) transporter 39 236 7.5E-27 T 12-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 VAPA_1c40840 705daa94b5f05ae8e5fd2429c8646bf6 450 Pfam PF00083 Sugar (and other) transporter 241 434 1.2E-10 T 12-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 VAPA_1c40840 705daa94b5f05ae8e5fd2429c8646bf6 450 TIGRFAM TIGR00883 2A0106: MFS transporter, metabolite:H+ symporter (MHS) family protein 45 432 3.9E-139 T 12-10-2018 IPR004736 MFS transporter, metabolite:H symporter GO:0016021|GO:0022857|GO:0055085 VAPA_1c40840 705daa94b5f05ae8e5fd2429c8646bf6 450 ProSitePatterns PS00217 Sugar transport proteins signature 2. 148 173 - T 12-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 VAPA_2c01580 578ec028133fdbb4c796c5c63c0bf89d 160 Pfam PF13577 SnoaL-like domain 15 142 3.3E-20 T 12-10-2018 IPR037401 SnoaL-like domain VAPA_2c01580 578ec028133fdbb4c796c5c63c0bf89d 160 Gene3D G3DSA:3.10.450.50 12 158 1.1E-26 T 12-10-2018 VAPA_2c01580 578ec028133fdbb4c796c5c63c0bf89d 160 SUPERFAMILY SSF54427 15 152 7.23E-25 T 12-10-2018 IPR032710 NTF2-like domain superfamily VAPA_1c29750 73685bbce69c427693af53f5e36db2a5 203 SUPERFAMILY SSF53448 1 195 1.25E-35 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases VAPA_1c29750 73685bbce69c427693af53f5e36db2a5 203 Pfam PF01128 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 2 195 6.1E-45 T 12-10-2018 IPR034683 Cytidylyltransferase IspD/TarI GO:0070567 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 VAPA_1c29750 73685bbce69c427693af53f5e36db2a5 203 ProSitePatterns PS01295 4-diphosphocytidyl-2C-methyl-D-erythritol synthase signature. 74 81 - T 12-10-2018 IPR018294 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, conserved site GO:0003824|GO:0008299 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 VAPA_1c29750 73685bbce69c427693af53f5e36db2a5 203 Gene3D G3DSA:3.90.550.10 1 199 1.4E-51 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases VAPA_1c54420 5eec84e20d9ab86df9fceb6ff0f822e0 552 Pfam PF00005 ABC transporter 35 193 1.4E-26 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c54420 5eec84e20d9ab86df9fceb6ff0f822e0 552 ProSitePatterns PS00211 ABC transporters family signature. 166 180 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_1c54420 5eec84e20d9ab86df9fceb6ff0f822e0 552 ProSitePatterns PS00211 ABC transporters family signature. 434 448 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_1c54420 5eec84e20d9ab86df9fceb6ff0f822e0 552 Pfam PF00005 ABC transporter 313 461 6.1E-30 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c54420 5eec84e20d9ab86df9fceb6ff0f822e0 552 SUPERFAMILY SSF52540 286 533 5.09E-69 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c54420 5eec84e20d9ab86df9fceb6ff0f822e0 552 SUPERFAMILY SSF52540 15 265 3.77E-63 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c54420 5eec84e20d9ab86df9fceb6ff0f822e0 552 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 245 277 9.6E-8 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 VAPA_1c54420 5eec84e20d9ab86df9fceb6ff0f822e0 552 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 513 544 2.7E-5 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 VAPA_1c54420 5eec84e20d9ab86df9fceb6ff0f822e0 552 SMART SM00382 321 511 1.3E-10 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c54420 5eec84e20d9ab86df9fceb6ff0f822e0 552 SMART SM00382 43 243 4.3E-15 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c54420 5eec84e20d9ab86df9fceb6ff0f822e0 552 Gene3D G3DSA:3.40.50.300 286 550 3.4E-82 T 12-10-2018 VAPA_1c54420 5eec84e20d9ab86df9fceb6ff0f822e0 552 Gene3D G3DSA:3.40.50.300 12 285 1.1E-84 T 12-10-2018 VAPA_1c30990 45d9015c4bb911dcd9b945430718cecf 325 Gene3D G3DSA:3.40.190.290 97 304 6.2E-41 T 12-10-2018 VAPA_1c30990 45d9015c4bb911dcd9b945430718cecf 325 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 35 45 1.3E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c30990 45d9015c4bb911dcd9b945430718cecf 325 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 24 35 1.3E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c30990 45d9015c4bb911dcd9b945430718cecf 325 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 45 56 1.3E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c30990 45d9015c4bb911dcd9b945430718cecf 325 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 9 68 9.5E-23 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c30990 45d9015c4bb911dcd9b945430718cecf 325 Gene3D G3DSA:1.10.10.10 7 95 2.0E-25 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c30990 45d9015c4bb911dcd9b945430718cecf 325 Pfam PF03466 LysR substrate binding domain 95 297 8.2E-47 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_1c30990 45d9015c4bb911dcd9b945430718cecf 325 SUPERFAMILY SSF46785 7 111 2.18E-24 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c30990 45d9015c4bb911dcd9b945430718cecf 325 SUPERFAMILY SSF53850 96 300 8.93E-45 T 12-10-2018 VAPA_1c44930 2cf778b97a57b122d3db9a9349df6036 304 Pfam PF13672 Protein phosphatase 2C 12 191 6.8E-14 T 12-10-2018 VAPA_1c44930 2cf778b97a57b122d3db9a9349df6036 304 SUPERFAMILY SSF81606 1 237 8.37E-50 T 12-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 VAPA_1c44930 2cf778b97a57b122d3db9a9349df6036 304 SMART SM00331 3 238 1.4E-15 T 12-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 VAPA_1c44930 2cf778b97a57b122d3db9a9349df6036 304 Gene3D G3DSA:3.60.40.10 1 239 1.0E-51 T 12-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 VAPA_1c44930 2cf778b97a57b122d3db9a9349df6036 304 SMART SM00332 2 236 1.3E-14 T 12-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 VAPA_1c01820 85bafa3cc5ab389b1715fc86e6ccd9d2 410 SUPERFAMILY SSF53686 8 320 7.86E-92 T 12-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme VAPA_1c01820 85bafa3cc5ab389b1715fc86e6ccd9d2 410 Gene3D G3DSA:3.30.70.260 333 403 9.6E-6 T 12-10-2018 VAPA_1c01820 85bafa3cc5ab389b1715fc86e6ccd9d2 410 SUPERFAMILY SSF55021 335 397 1.0E-5 T 12-10-2018 VAPA_1c01820 85bafa3cc5ab389b1715fc86e6ccd9d2 410 Gene3D G3DSA:3.40.50.1100 10 315 3.2E-107 T 12-10-2018 VAPA_1c01820 85bafa3cc5ab389b1715fc86e6ccd9d2 410 Gene3D G3DSA:3.40.50.1100 53 156 3.2E-107 T 12-10-2018 VAPA_1c01820 85bafa3cc5ab389b1715fc86e6ccd9d2 410 TIGRFAM TIGR01127 ilvA_1Cterm: threonine ammonia-lyase 24 406 1.9E-126 T 12-10-2018 IPR005789 Threonine dehydratase, catabolic GO:0004794|GO:0006567 KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 VAPA_1c01820 85bafa3cc5ab389b1715fc86e6ccd9d2 410 Pfam PF01842 ACT domain 335 366 1.8E-6 T 12-10-2018 IPR002912 ACT domain VAPA_1c01820 85bafa3cc5ab389b1715fc86e6ccd9d2 410 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 19 311 1.8E-75 T 12-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme VAPA_2c11600 35ac99b59a9e12d31cc1e98fa3576e8e 384 TIGRFAM TIGR02318 phosphono_phnM: phosphonate metabolism protein PhnM 7 383 2.6E-137 T 12-10-2018 IPR012696 Phosphonate metabolism PhnM GO:0019700 KEGG: 00440+3.6.1.63|MetaCyc: PWY-7399|MetaCyc: PWY-7805|MetaCyc: PWY-7807 VAPA_2c11600 35ac99b59a9e12d31cc1e98fa3576e8e 384 SUPERFAMILY SSF51338 2 383 1.63E-11 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 VAPA_2c11600 35ac99b59a9e12d31cc1e98fa3576e8e 384 Gene3D G3DSA:2.30.40.10 6 51 3.6E-7 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 VAPA_2c11600 35ac99b59a9e12d31cc1e98fa3576e8e 384 Gene3D G3DSA:2.30.40.10 347 363 2.5E-9 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 VAPA_2c11600 35ac99b59a9e12d31cc1e98fa3576e8e 384 SUPERFAMILY SSF51556 53 346 7.75E-17 T 12-10-2018 IPR032466 Metal-dependent hydrolase VAPA_2c11600 35ac99b59a9e12d31cc1e98fa3576e8e 384 Gene3D G3DSA:3.20.20.140 52 98 3.6E-7 T 12-10-2018 VAPA_2c11600 35ac99b59a9e12d31cc1e98fa3576e8e 384 PIRSF PIRSF038971 3 384 7.2E-141 T 12-10-2018 IPR012696 Phosphonate metabolism PhnM GO:0019700 KEGG: 00440+3.6.1.63|MetaCyc: PWY-7399|MetaCyc: PWY-7805|MetaCyc: PWY-7807 VAPA_2c11600 35ac99b59a9e12d31cc1e98fa3576e8e 384 Pfam PF07969 Amidohydrolase family 213 384 1.9E-11 T 12-10-2018 IPR013108 Amidohydrolase 3 VAPA_2c11600 35ac99b59a9e12d31cc1e98fa3576e8e 384 Gene3D G3DSA:3.20.20.140 255 346 2.5E-9 T 12-10-2018 VAPA_1c32870 65a3bf1a17acb923d5500d577476b634 295 Gene3D G3DSA:3.40.50.1820 6 248 1.1E-13 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c32870 65a3bf1a17acb923d5500d577476b634 295 SUPERFAMILY SSF53474 32 146 1.52E-13 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c00530 1ec83e37293908a0af08c70e98294f27 201 ProDom PD007457 TRANSFERASE ADENOSYLTRANSFERASE COBALAMIN ATP:COBIALAMIN ADENOSYLTRANSFERASE PDUO TYPE RELATED ACIDURIA YVQK 23 177 1.0E-54 T 12-10-2018 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 VAPA_1c00530 1ec83e37293908a0af08c70e98294f27 201 Pfam PF01923 Cobalamin adenosyltransferase 8 165 1.1E-53 T 12-10-2018 IPR016030 Cobalamin adenosyltransferase-like KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 VAPA_1c00530 1ec83e37293908a0af08c70e98294f27 201 Gene3D G3DSA:1.20.1200.10 17 183 5.8E-58 T 12-10-2018 IPR036451 Cobalamin adenosyltransferase-like superfamily KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 VAPA_1c00530 1ec83e37293908a0af08c70e98294f27 201 SUPERFAMILY SSF89028 7 178 3.73E-58 T 12-10-2018 IPR036451 Cobalamin adenosyltransferase-like superfamily KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 VAPA_1c00530 1ec83e37293908a0af08c70e98294f27 201 TIGRFAM TIGR00636 PduO_Nterm: ATP:cob(I)alamin adenosyltransferase 10 178 1.1E-55 T 12-10-2018 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 VAPA_1c14470 f667735a829d1bb095bef370fe49149e 250 Pfam PF10099 Anti-sigma-K factor rskA 63 243 2.4E-28 T 12-10-2018 IPR018764 Anti-sigma K factor RskA GO:0005886|GO:0016021 VAPA_1c50460 075dcda459223066adbd55ee44c3509a 375 Gene3D G3DSA:3.30.360.10 134 372 3.9E-131 T 12-10-2018 VAPA_1c50460 075dcda459223066adbd55ee44c3509a 375 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 1 129 2.8E-18 T 12-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 VAPA_1c50460 075dcda459223066adbd55ee44c3509a 375 Gene3D G3DSA:3.40.50.720 2 348 3.9E-131 T 12-10-2018 VAPA_1c50460 075dcda459223066adbd55ee44c3509a 375 SUPERFAMILY SSF51735 9 161 3.05E-34 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c50460 075dcda459223066adbd55ee44c3509a 375 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 141 262 1.6E-4 T 12-10-2018 IPR004104 Oxidoreductase, C-terminal GO:0016491|GO:0055114 VAPA_1c50460 075dcda459223066adbd55ee44c3509a 375 SUPERFAMILY SSF55347 135 317 8.83E-37 T 12-10-2018 VAPA_1c28580 a84d753510e3515b0110226ffce02dcd 155 Pfam PF02590 Predicted SPOUT methyltransferase 1 153 9.8E-47 T 12-10-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 VAPA_1c28580 a84d753510e3515b0110226ffce02dcd 155 Gene3D G3DSA:3.40.1280.10 1 155 6.6E-47 T 12-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal VAPA_1c28580 a84d753510e3515b0110226ffce02dcd 155 SUPERFAMILY SSF75217 1 152 9.42E-46 T 12-10-2018 IPR029028 Alpha/beta knot methyltransferases VAPA_1c28580 a84d753510e3515b0110226ffce02dcd 155 PIRSF PIRSF004505 1 154 1.2E-42 T 12-10-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 VAPA_1c28580 a84d753510e3515b0110226ffce02dcd 155 Hamap MF_00658 Ribosomal RNA large subunit methyltransferase H [rlmH]. 1 154 26.756 T 12-10-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 VAPA_1c26500 0c8b8bbee2e24c81a2024c96a1cea59b 1025 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 660 671 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site VAPA_1c26500 0c8b8bbee2e24c81a2024c96a1cea59b 1025 Pfam PF13183 4Fe-4S dicluster domain 597 674 1.2E-9 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain VAPA_1c26500 0c8b8bbee2e24c81a2024c96a1cea59b 1025 SUPERFAMILY SSF56176 27 283 2.7E-51 T 12-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 VAPA_1c26500 0c8b8bbee2e24c81a2024c96a1cea59b 1025 Gene3D G3DSA:3.40.462.40 283 328 1.4E-6 T 12-10-2018 VAPA_1c26500 0c8b8bbee2e24c81a2024c96a1cea59b 1025 SUPERFAMILY SSF46548 597 679 2.77E-8 T 12-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 VAPA_1c26500 0c8b8bbee2e24c81a2024c96a1cea59b 1025 Gene3D G3DSA:3.30.70.2740 412 492 3.6E-5 T 12-10-2018 VAPA_1c26500 0c8b8bbee2e24c81a2024c96a1cea59b 1025 Pfam PF02913 FAD linked oxidases, C-terminal domain 283 532 3.8E-52 T 12-10-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 VAPA_1c26500 0c8b8bbee2e24c81a2024c96a1cea59b 1025 Pfam PF02754 Cysteine-rich domain 792 866 0.0075 T 12-10-2018 IPR004017 Cysteine-rich domain VAPA_1c26500 0c8b8bbee2e24c81a2024c96a1cea59b 1025 Pfam PF02754 Cysteine-rich domain 940 996 0.027 T 12-10-2018 IPR004017 Cysteine-rich domain VAPA_1c26500 0c8b8bbee2e24c81a2024c96a1cea59b 1025 Gene3D G3DSA:1.10.45.10 493 533 4.0E-5 T 12-10-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 VAPA_1c26500 0c8b8bbee2e24c81a2024c96a1cea59b 1025 SUPERFAMILY SSF55103 287 540 7.52E-57 T 12-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 VAPA_1c26500 0c8b8bbee2e24c81a2024c96a1cea59b 1025 Pfam PF01565 FAD binding domain 61 195 3.0E-34 T 12-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 VAPA_1c26500 0c8b8bbee2e24c81a2024c96a1cea59b 1025 Gene3D G3DSA:3.30.465.40 255 282 1.4E-6 T 12-10-2018 VAPA_1c26500 0c8b8bbee2e24c81a2024c96a1cea59b 1025 Gene3D G3DSA:3.30.465.40 28 213 2.3E-36 T 12-10-2018 VAPA_1c33130 d2b2794198a48bad67c36e1d9044cd7e 280 SUPERFAMILY SSF46785 26 99 4.3E-12 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c33130 d2b2794198a48bad67c36e1d9044cd7e 280 SUPERFAMILY SSF55781 97 272 3.01E-36 T 12-10-2018 VAPA_1c33130 d2b2794198a48bad67c36e1d9044cd7e 280 Pfam PF01614 Bacterial transcriptional regulator 145 268 1.9E-11 T 12-10-2018 IPR014757 Transcription regulator IclR, C-terminal VAPA_1c33130 d2b2794198a48bad67c36e1d9044cd7e 280 SMART SM00346 26 116 5.4E-19 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 VAPA_1c33130 d2b2794198a48bad67c36e1d9044cd7e 280 Gene3D G3DSA:3.30.450.40 100 268 6.4E-35 T 12-10-2018 IPR029016 GAF-like domain superfamily VAPA_1c33130 d2b2794198a48bad67c36e1d9044cd7e 280 Gene3D G3DSA:1.10.10.10 11 93 1.3E-18 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c33130 d2b2794198a48bad67c36e1d9044cd7e 280 Pfam PF09339 IclR helix-turn-helix domain 28 76 9.3E-14 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 VAPA_1c53300 45a9741b5509519c494abd69eb92259a 216 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 27 40 9.4E-7 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 VAPA_1c53300 45a9741b5509519c494abd69eb92259a 216 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 48 71 9.4E-7 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 VAPA_1c53300 45a9741b5509519c494abd69eb92259a 216 Pfam PF00440 Bacterial regulatory proteins, tetR family 29 72 2.7E-10 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 VAPA_1c53300 45a9741b5509519c494abd69eb92259a 216 Pfam PF08362 YcdC-like protein, C-terminal region 74 214 1.3E-29 T 12-10-2018 IPR013573 Transcription regulator YcdC, C-terminal GO:0045892 VAPA_1c53300 45a9741b5509519c494abd69eb92259a 216 Gene3D G3DSA:1.10.357.10 74 215 5.8E-36 T 12-10-2018 VAPA_1c53300 45a9741b5509519c494abd69eb92259a 216 SUPERFAMILY SSF46689 14 86 6.67E-14 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 VAPA_1c53300 45a9741b5509519c494abd69eb92259a 216 SUPERFAMILY SSF48498 93 214 1.02E-26 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily VAPA_1c53300 45a9741b5509519c494abd69eb92259a 216 Gene3D G3DSA:1.10.10.60 6 73 6.2E-16 T 12-10-2018 VAPA_2c04480 912875d528f8e4f8010c140f0420f544 410 Gene3D G3DSA:3.20.20.70 29 408 1.4E-52 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 VAPA_2c04480 912875d528f8e4f8010c140f0420f544 410 SUPERFAMILY SSF51412 31 377 8.09E-37 T 12-10-2018 VAPA_2c04480 912875d528f8e4f8010c140f0420f544 410 Pfam PF03060 Nitronate monooxygenase 32 316 5.4E-30 T 12-10-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 VAPA_1c54920 0947e5793520fd92615160687f4ac8f4 278 SUPERFAMILY SSF53474 7 275 6.35E-39 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c54920 0947e5793520fd92615160687f4ac8f4 278 Gene3D G3DSA:3.40.50.1820 3 276 2.9E-60 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c54920 0947e5793520fd92615160687f4ac8f4 278 Pfam PF12146 Serine aminopeptidase, S33 25 259 5.4E-68 T 12-10-2018 IPR022742 Serine aminopeptidase, S33 VAPA_1c04090 9ff356c0a3fba2dd7cb5e9f54d37fc0b 497 Pfam PF00005 ABC transporter 17 167 5.8E-25 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c04090 9ff356c0a3fba2dd7cb5e9f54d37fc0b 497 SMART SM00382 26 214 6.5E-9 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c04090 9ff356c0a3fba2dd7cb5e9f54d37fc0b 497 SMART SM00382 277 470 0.001 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c04090 9ff356c0a3fba2dd7cb5e9f54d37fc0b 497 SUPERFAMILY SSF52540 272 480 1.33E-39 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c04090 9ff356c0a3fba2dd7cb5e9f54d37fc0b 497 SUPERFAMILY SSF52540 2 216 4.05E-57 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c04090 9ff356c0a3fba2dd7cb5e9f54d37fc0b 497 ProSitePatterns PS00211 ABC transporters family signature. 395 409 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_1c04090 9ff356c0a3fba2dd7cb5e9f54d37fc0b 497 Pfam PF00005 ABC transporter 272 422 7.5E-15 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c04090 9ff356c0a3fba2dd7cb5e9f54d37fc0b 497 Gene3D G3DSA:3.40.50.300 254 488 1.9E-37 T 12-10-2018 VAPA_1c04090 9ff356c0a3fba2dd7cb5e9f54d37fc0b 497 Gene3D G3DSA:3.40.50.300 1 229 1.4E-55 T 12-10-2018 VAPA_1c12860 5fcad062e159df4da9c476d9e8b8f261 288 SUPERFAMILY SSF88713 14 262 3.78E-47 T 12-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 VAPA_1c12860 5fcad062e159df4da9c476d9e8b8f261 288 Gene3D G3DSA:3.20.20.370 11 262 3.9E-27 T 12-10-2018 VAPA_1c12860 5fcad062e159df4da9c476d9e8b8f261 288 Pfam PF04794 YdjC-like protein 16 260 1.4E-37 T 12-10-2018 IPR006879 Carbohydrate deacetylase YdjC-like VAPA_1c38230 1defe02bef8581711c228b0ec918ff6e 231 SUPERFAMILY SSF55469 15 229 5.1E-42 T 12-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 VAPA_1c38230 1defe02bef8581711c228b0ec918ff6e 231 Gene3D G3DSA:3.40.109.10 5 227 9.3E-61 T 12-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 VAPA_1c38230 1defe02bef8581711c228b0ec918ff6e 231 Pfam PF00881 Nitroreductase family 20 206 1.6E-29 T 12-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 VAPA_1c28340 0f7ffa382355c690b040461a2b9d9e47 391 Gene3D G3DSA:3.90.1150.10 26 388 4.2E-133 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 VAPA_1c28340 0f7ffa382355c690b040461a2b9d9e47 391 SUPERFAMILY SSF53383 14 390 1.1E-101 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase VAPA_1c28340 0f7ffa382355c690b040461a2b9d9e47 391 Pfam PF00155 Aminotransferase class I and II 36 388 8.9E-55 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 VAPA_1c28340 0f7ffa382355c690b040461a2b9d9e47 391 Gene3D G3DSA:3.40.640.10 50 288 4.2E-133 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 VAPA_1c21450 2da0b02cb639be14372080bd0ef97bca 303 SUPERFAMILY SSF46785 1 113 1.14E-22 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c21450 2da0b02cb639be14372080bd0ef97bca 303 Gene3D G3DSA:1.10.10.10 2 91 2.2E-21 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c21450 2da0b02cb639be14372080bd0ef97bca 303 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 64 6.6E-15 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c21450 2da0b02cb639be14372080bd0ef97bca 303 Pfam PF03466 LysR substrate binding domain 89 291 9.0E-40 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_1c21450 2da0b02cb639be14372080bd0ef97bca 303 SUPERFAMILY SSF53850 90 297 3.04E-41 T 12-10-2018 VAPA_1c21450 2da0b02cb639be14372080bd0ef97bca 303 Gene3D G3DSA:3.40.190.290 92 300 1.1E-40 T 12-10-2018 VAPA_1c41580 e1daf4eb9f76dd3a097fa7700c2f8e54 292 Gene3D G3DSA:3.40.50.300 47 292 1.0E-53 T 12-10-2018 VAPA_1c41580 e1daf4eb9f76dd3a097fa7700c2f8e54 292 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 270 291 1.2E-8 T 12-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal VAPA_1c41580 e1daf4eb9f76dd3a097fa7700c2f8e54 292 SUPERFAMILY SSF52540 51 290 5.54E-54 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c41580 e1daf4eb9f76dd3a097fa7700c2f8e54 292 Pfam PF00005 ABC transporter 68 222 1.3E-28 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c41580 e1daf4eb9f76dd3a097fa7700c2f8e54 292 SMART SM00382 76 292 7.4E-4 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c41580 e1daf4eb9f76dd3a097fa7700c2f8e54 292 TIGRFAM TIGR03411 urea_trans_UrtD: urea ABC transporter, ATP-binding protein UrtD 51 292 2.9E-117 T 12-10-2018 IPR017781 ABC transporter, urea, ATP-binding protein, UrtD VAPA_1c11820 14764a004a466d2c119aa4e4b00ace79 243 PIRSF PIRSF039085 1 241 1.0E-113 T 12-10-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 VAPA_1c11820 14764a004a466d2c119aa4e4b00ace79 243 SUPERFAMILY SSF52540 1 235 4.11E-77 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c11820 14764a004a466d2c119aa4e4b00ace79 243 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_1c11820 14764a004a466d2c119aa4e4b00ace79 243 Gene3D G3DSA:3.40.50.300 1 241 1.5E-78 T 12-10-2018 VAPA_1c11820 14764a004a466d2c119aa4e4b00ace79 243 SMART SM00382 26 213 1.7E-16 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c11820 14764a004a466d2c119aa4e4b00ace79 243 Pfam PF00005 ABC transporter 17 165 5.6E-34 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c36340 38c2dc8952aa7efc525fb6d0c031574f 433 SMART SM01012 140 195 2.6E-21 T 12-10-2018 IPR005561 ANTAR domain GO:0003723 VAPA_1c36340 38c2dc8952aa7efc525fb6d0c031574f 433 Pfam PF13675 Type IV pili methyl-accepting chemotaxis transducer N-term 314 394 2.8E-11 T 12-10-2018 IPR029095 NarX-like, N-terminal VAPA_1c36340 38c2dc8952aa7efc525fb6d0c031574f 433 Pfam PF13675 Type IV pili methyl-accepting chemotaxis transducer N-term 201 278 5.4E-7 T 12-10-2018 IPR029095 NarX-like, N-terminal VAPA_1c36340 38c2dc8952aa7efc525fb6d0c031574f 433 SUPERFAMILY SSF52172 23 195 9.44E-17 T 12-10-2018 IPR011006 CheY-like superfamily VAPA_1c36340 38c2dc8952aa7efc525fb6d0c031574f 433 Pfam PF03861 ANTAR domain 143 195 3.2E-17 T 12-10-2018 IPR005561 ANTAR domain GO:0003723 VAPA_1c36340 38c2dc8952aa7efc525fb6d0c031574f 433 Gene3D G3DSA:1.10.10.10 143 202 4.5E-15 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c26000 79d4efbd8f2cd99b6ff855d5aca40d23 1171 Gene3D G3DSA:3.40.50.300 3 334 2.8E-47 T 12-10-2018 VAPA_1c26000 79d4efbd8f2cd99b6ff855d5aca40d23 1171 Hamap MF_01894 Chromosome partition protein Smc [smc]. 1 1163 22.099 T 12-10-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 VAPA_1c26000 79d4efbd8f2cd99b6ff855d5aca40d23 1171 PIRSF PIRSF005719 1 1170 3.2E-241 T 12-10-2018 IPR024704 Structural maintenance of chromosomes protein VAPA_1c26000 79d4efbd8f2cd99b6ff855d5aca40d23 1171 SUPERFAMILY SSF52540 2 1161 6.39E-61 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c26000 79d4efbd8f2cd99b6ff855d5aca40d23 1171 TIGRFAM TIGR02168 SMC_prok_B: chromosome segregation protein SMC 2 1161 0.0 T 12-10-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 VAPA_1c26000 79d4efbd8f2cd99b6ff855d5aca40d23 1171 Pfam PF02463 RecF/RecN/SMC N terminal domain 3 1154 4.4E-64 T 12-10-2018 IPR003395 RecF/RecN/SMC, N-terminal VAPA_1c26000 79d4efbd8f2cd99b6ff855d5aca40d23 1171 SMART SM00968 518 624 9.8E-5 T 12-10-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 VAPA_1c08740 28eed518bd91133126293ccf51c1c936 143 SUPERFAMILY SSF52980 10 122 2.95E-21 T 12-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 VAPA_1c08740 28eed518bd91133126293ccf51c1c936 143 Pfam PF04480 Protein of unknown function (DUF559) 12 117 2.4E-38 T 12-10-2018 IPR007569 Protein of unknown function DUF559 VAPA_1c08740 28eed518bd91133126293ccf51c1c936 143 Gene3D G3DSA:3.40.960.10 20 121 1.1E-30 T 12-10-2018 VAPA_1c13750 09d9ed76a03de66688ee6d51e1029c13 279 SMART SM00702 92 274 1.1E-43 T 12-10-2018 IPR006620 Prolyl 4-hydroxylase, alpha subunit GO:0005506|GO:0016705|GO:0031418|GO:0055114 VAPA_1c13750 09d9ed76a03de66688ee6d51e1029c13 279 Pfam PF13640 2OG-Fe(II) oxygenase superfamily 172 274 8.8E-17 T 12-10-2018 IPR005123 Oxoglutarate/iron-dependent dioxygenase GO:0016491|GO:0055114 VAPA_1c13750 09d9ed76a03de66688ee6d51e1029c13 279 Gene3D G3DSA:2.60.120.620 78 275 1.9E-55 T 12-10-2018 VAPA_1c42790 564716374d96d48eaae13b72a0eb5c18 114 SMART SM00834 1 42 1.7E-18 T 12-10-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain VAPA_1c42790 564716374d96d48eaae13b72a0eb5c18 114 TIGRFAM TIGR02605 CxxC_CxxC_SSSS: putative regulatory protein, FmdB family 1 52 1.2E-21 T 12-10-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain VAPA_1c42790 564716374d96d48eaae13b72a0eb5c18 114 Pfam PF09723 Zinc ribbon domain 1 41 1.3E-15 T 12-10-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain VAPA_1c43120 9d5327e302b8e93620e1c3f5781406f3 675 Pfam PF01584 CheW-like domain 524 650 1.6E-24 T 12-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 VAPA_1c43120 9d5327e302b8e93620e1c3f5781406f3 675 Gene3D G3DSA:2.30.30.40 519 647 3.9E-38 T 12-10-2018 VAPA_1c43120 9d5327e302b8e93620e1c3f5781406f3 675 Gene3D G3DSA:2.40.50.180 542 606 3.9E-38 T 12-10-2018 VAPA_1c43120 9d5327e302b8e93620e1c3f5781406f3 675 SMART SM00260 511 651 3.6E-35 T 12-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 VAPA_1c43120 9d5327e302b8e93620e1c3f5781406f3 675 SUPERFAMILY SSF55052 160 224 3.14E-20 T 12-10-2018 IPR035891 CheY-binding domain of CheA VAPA_1c43120 9d5327e302b8e93620e1c3f5781406f3 675 SUPERFAMILY SSF55874 337 517 1.05E-35 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_1c43120 9d5327e302b8e93620e1c3f5781406f3 675 Gene3D G3DSA:1.10.287.560 271 334 2.6E-18 T 12-10-2018 IPR037006 Histidine kinase CheA-like, homodimeric domain superfamily GO:0000155|GO:0006935 VAPA_1c43120 9d5327e302b8e93620e1c3f5781406f3 675 SUPERFAMILY SSF47226 3 124 5.07E-31 T 12-10-2018 IPR036641 HPT domain superfamily GO:0000160 VAPA_1c43120 9d5327e302b8e93620e1c3f5781406f3 675 SMART SM00073 3 100 3.0E-29 T 12-10-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160 VAPA_1c43120 9d5327e302b8e93620e1c3f5781406f3 675 SMART SM00387 379 519 1.2E-23 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase VAPA_1c43120 9d5327e302b8e93620e1c3f5781406f3 675 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 382 518 1.2E-17 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase VAPA_1c43120 9d5327e302b8e93620e1c3f5781406f3 675 Gene3D G3DSA:3.30.70.400 156 226 6.4E-21 T 12-10-2018 IPR035891 CheY-binding domain of CheA VAPA_1c43120 9d5327e302b8e93620e1c3f5781406f3 675 SMART SM01231 271 334 3.9E-22 T 12-10-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 VAPA_1c43120 9d5327e302b8e93620e1c3f5781406f3 675 Gene3D G3DSA:3.30.565.10 335 518 3.1E-54 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_1c43120 9d5327e302b8e93620e1c3f5781406f3 675 Pfam PF09078 CheY binding 161 223 3.8E-24 T 12-10-2018 IPR015162 CheY binding VAPA_1c43120 9d5327e302b8e93620e1c3f5781406f3 675 Gene3D G3DSA:1.20.120.160 1 140 1.2E-42 T 12-10-2018 IPR036641 HPT domain superfamily GO:0000160 VAPA_1c43120 9d5327e302b8e93620e1c3f5781406f3 675 SUPERFAMILY SSF50341 518 650 3.92E-30 T 12-10-2018 IPR036061 CheW-like domain superfamily GO:0006935|GO:0007165 VAPA_1c43120 9d5327e302b8e93620e1c3f5781406f3 675 PRINTS PR00344 Bacterial sensor protein C-terminal signature 463 473 3.0E-13 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c43120 9d5327e302b8e93620e1c3f5781406f3 675 PRINTS PR00344 Bacterial sensor protein C-terminal signature 503 516 3.0E-13 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c43120 9d5327e302b8e93620e1c3f5781406f3 675 PRINTS PR00344 Bacterial sensor protein C-terminal signature 424 438 3.0E-13 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c43120 9d5327e302b8e93620e1c3f5781406f3 675 PRINTS PR00344 Bacterial sensor protein C-terminal signature 479 497 3.0E-13 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c43120 9d5327e302b8e93620e1c3f5781406f3 675 Pfam PF02895 Signal transducing histidine kinase, homodimeric domain 271 334 7.1E-19 T 12-10-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 VAPA_1c43120 9d5327e302b8e93620e1c3f5781406f3 675 Pfam PF01627 Hpt domain 7 102 1.9E-18 T 12-10-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160 VAPA_1c43120 9d5327e302b8e93620e1c3f5781406f3 675 SUPERFAMILY SSF47384 272 335 3.1E-15 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 VAPA_1c43940 456d95c03845d5514ba494ef9773ddfc 306 SUPERFAMILY SSF53850 92 296 1.71E-31 T 12-10-2018 VAPA_1c43940 456d95c03845d5514ba494ef9773ddfc 306 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 2.3E-7 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c43940 456d95c03845d5514ba494ef9773ddfc 306 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 2.3E-7 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c43940 456d95c03845d5514ba494ef9773ddfc 306 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 2.3E-7 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c43940 456d95c03845d5514ba494ef9773ddfc 306 Gene3D G3DSA:3.40.190.290 92 301 3.3E-24 T 12-10-2018 VAPA_1c43940 456d95c03845d5514ba494ef9773ddfc 306 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 62 2.6E-18 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c43940 456d95c03845d5514ba494ef9773ddfc 306 Pfam PF03466 LysR substrate binding domain 92 294 1.4E-32 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_1c43940 456d95c03845d5514ba494ef9773ddfc 306 Gene3D G3DSA:1.10.10.10 1 90 4.4E-19 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c43940 456d95c03845d5514ba494ef9773ddfc 306 SUPERFAMILY SSF46785 2 82 4.23E-19 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c32820 0d37c7829b2f570646ac645320cead5a 257 SUPERFAMILY SSF53335 74 230 1.99E-6 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase VAPA_1c32820 0d37c7829b2f570646ac645320cead5a 257 Gene3D G3DSA:3.40.50.150 73 234 2.7E-7 T 12-10-2018 VAPA_1c32820 0d37c7829b2f570646ac645320cead5a 257 TIGRFAM TIGR04325 MTase_LIC12133: putative methyltransferase, LIC12133 family 28 254 1.1E-66 T 12-10-2018 IPR027612 Putative methyltransferase, LIC12133 family VAPA_1c31630 ac86f9f2e535dda991b7f1370ec3924e 263 Pfam PF06167 Glucose-regulated metallo-peptidase M90 7 259 7.2E-81 T 12-10-2018 IPR010384 MtfA family VAPA_1c31630 ac86f9f2e535dda991b7f1370ec3924e 263 Gene3D G3DSA:1.10.472.150 15 141 1.6E-40 T 12-10-2018 VAPA_1c31630 ac86f9f2e535dda991b7f1370ec3924e 263 Gene3D G3DSA:3.40.390.10 145 263 5.9E-34 T 12-10-2018 IPR024079 Metallopeptidase, catalytic domain superfamily GO:0008237 VAPA_1c31630 ac86f9f2e535dda991b7f1370ec3924e 263 SUPERFAMILY SSF55486 37 258 1.76E-34 T 12-10-2018 VAPA_2c02810 c66f057dc69c382b43ce0a99c182c666 114 Gene3D G3DSA:1.20.1300.10 1 113 2.1E-8 T 12-10-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 VAPA_2c02810 c66f057dc69c382b43ce0a99c182c666 114 Pfam PF01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 3 104 2.2E-10 T 12-10-2018 IPR000701 Succinate dehydrogenase/fumarate reductase type B, transmembrane subunit GO:0016627 Reactome: R-HSA-611105|Reactome: R-HSA-71403 VAPA_2c02810 c66f057dc69c382b43ce0a99c182c666 114 SUPERFAMILY SSF81343 4 98 5.01E-13 T 12-10-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 VAPA_1c18500 917a93c64ef1bef901d5603af6c50ae9 665 SUPERFAMILY SSF57783 6 104 8.16E-37 T 12-10-2018 VAPA_1c18500 917a93c64ef1bef901d5603af6c50ae9 665 Gene3D G3DSA:3.90.580.10 6 106 2.0E-37 T 12-10-2018 IPR036977 DNA Primase, CHC2-type zinc finger GO:0003677|GO:0006260|GO:0008270 VAPA_1c18500 917a93c64ef1bef901d5603af6c50ae9 665 Gene3D G3DSA:3.90.980.10 117 249 1.0E-38 T 12-10-2018 IPR037068 DNA primase, catalytic core, N-terminal domain superfamily VAPA_1c18500 917a93c64ef1bef901d5603af6c50ae9 665 Hamap MF_00974 DNA primase [dnaG]. 8 650 27.674 T 12-10-2018 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 VAPA_1c18500 917a93c64ef1bef901d5603af6c50ae9 665 Gene3D G3DSA:3.40.1360.10 250 376 7.6E-41 T 12-10-2018 VAPA_1c18500 917a93c64ef1bef901d5603af6c50ae9 665 SMART SM00493 268 339 4.4E-13 T 12-10-2018 IPR006171 TOPRIM domain VAPA_1c18500 917a93c64ef1bef901d5603af6c50ae9 665 Pfam PF13662 Toprim domain 270 340 1.5E-14 T 12-10-2018 IPR006171 TOPRIM domain VAPA_1c18500 917a93c64ef1bef901d5603af6c50ae9 665 Pfam PF01807 CHC2 zinc finger 10 104 5.6E-38 T 12-10-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 VAPA_1c18500 917a93c64ef1bef901d5603af6c50ae9 665 Pfam PF08275 DNA primase catalytic core, N-terminal domain 135 261 6.6E-36 T 12-10-2018 IPR013264 DNA primase, catalytic core, N-terminal VAPA_1c18500 917a93c64ef1bef901d5603af6c50ae9 665 TIGRFAM TIGR01391 dnaG: DNA primase 9 426 4.9E-136 T 12-10-2018 IPR006295 DNA primase, DnaG GO:0003896|GO:0006269 VAPA_1c18500 917a93c64ef1bef901d5603af6c50ae9 665 SMART SM00400 40 94 1.6E-34 T 12-10-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 VAPA_1c18500 917a93c64ef1bef901d5603af6c50ae9 665 Pfam PF10410 DnaB-helicase binding domain of primase 378 431 2.1E-10 T 12-10-2018 IPR019475 DNA primase, DnaB-helicase binding domain GO:0016779 VAPA_1c18500 917a93c64ef1bef901d5603af6c50ae9 665 SUPERFAMILY SSF56731 124 430 2.88E-98 T 12-10-2018 VAPA_1c50210 8887a0500180775f2abde19daf90b1ac 234 Pfam PF00857 Isochorismatase family 26 216 2.7E-29 T 12-10-2018 IPR000868 Isochorismatase-like GO:0003824 VAPA_1c50210 8887a0500180775f2abde19daf90b1ac 234 SUPERFAMILY SSF52499 20 223 3.01E-40 T 12-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 VAPA_1c50210 8887a0500180775f2abde19daf90b1ac 234 Gene3D G3DSA:3.40.50.850 7 232 6.9E-41 T 12-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 VAPA_1c46430 da295a1a8d352d4b0faddb2c6aacd2a7 284 SUPERFAMILY SSF52540 7 239 8.11E-34 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c46430 da295a1a8d352d4b0faddb2c6aacd2a7 284 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 29 180 7.4E-13 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 VAPA_1c46430 da295a1a8d352d4b0faddb2c6aacd2a7 284 Gene3D G3DSA:3.40.50.300 10 194 2.6E-24 T 12-10-2018 VAPA_1c46430 da295a1a8d352d4b0faddb2c6aacd2a7 284 SMART SM00382 25 187 2.8E-6 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c01510 443601a0732f54e59b93ec8bdd293746 345 Pfam PF00795 Carbon-nitrogen hydrolase 15 268 3.5E-46 T 12-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 VAPA_1c01510 443601a0732f54e59b93ec8bdd293746 345 Gene3D G3DSA:3.60.110.10 1 345 7.4E-146 T 12-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily VAPA_1c01510 443601a0732f54e59b93ec8bdd293746 345 SUPERFAMILY SSF56317 13 275 3.4E-51 T 12-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily VAPA_2c06790 29a22c9adc18c9dd809c238a26c97f8b 271 Gene3D G3DSA:3.30.450.40 97 263 9.0E-29 T 12-10-2018 IPR029016 GAF-like domain superfamily VAPA_2c06790 29a22c9adc18c9dd809c238a26c97f8b 271 SMART SM00346 19 109 4.4E-16 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 VAPA_2c06790 29a22c9adc18c9dd809c238a26c97f8b 271 Gene3D G3DSA:1.10.10.10 13 87 1.1E-14 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_2c06790 29a22c9adc18c9dd809c238a26c97f8b 271 SUPERFAMILY SSF46785 19 92 3.04E-12 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_2c06790 29a22c9adc18c9dd809c238a26c97f8b 271 Pfam PF01614 Bacterial transcriptional regulator 139 263 4.8E-9 T 12-10-2018 IPR014757 Transcription regulator IclR, C-terminal VAPA_2c06790 29a22c9adc18c9dd809c238a26c97f8b 271 SUPERFAMILY SSF55781 79 269 9.16E-34 T 12-10-2018 VAPA_2c06790 29a22c9adc18c9dd809c238a26c97f8b 271 Pfam PF09339 IclR helix-turn-helix domain 21 71 4.8E-9 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 VAPA_1c06370 330d7f3fe3d7a2647abb4a95f677839a 350 Gene3D G3DSA:3.60.110.10 1 286 1.2E-116 T 12-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily VAPA_1c06370 330d7f3fe3d7a2647abb4a95f677839a 350 SUPERFAMILY SSF56317 6 300 8.63E-78 T 12-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily VAPA_1c06370 330d7f3fe3d7a2647abb4a95f677839a 350 TIGRFAM TIGR04048 nitrile_sll0784: putative nitrilase, sll0784 family 6 305 1.1E-176 T 12-10-2018 IPR023919 Nitrilase-related, sll0784 VAPA_1c06370 330d7f3fe3d7a2647abb4a95f677839a 350 ProSitePatterns PS00921 Nitrilases / cyanide hydratase active site signature. 160 173 - T 12-10-2018 IPR000132 Nitrilase/cyanide hydratase, conserved site GO:0016810 VAPA_1c06370 330d7f3fe3d7a2647abb4a95f677839a 350 Pfam PF00795 Carbon-nitrogen hydrolase 9 281 7.4E-56 T 12-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 VAPA_1c23170 b02e399fb0b817056d86ef78c17b998f 112 Gene3D G3DSA:3.10.20.30 1 112 2.9E-33 T 12-10-2018 IPR012675 Beta-grasp domain superfamily VAPA_1c23170 b02e399fb0b817056d86ef78c17b998f 112 TIGRFAM TIGR02007 fdx_isc: ferredoxin, 2Fe-2S type, ISC system 2 111 1.2E-53 T 12-10-2018 IPR011536 Ferredoxin 2Fe-2S type, proteobacteria GO:0009055|GO:0051537 VAPA_1c23170 b02e399fb0b817056d86ef78c17b998f 112 SUPERFAMILY SSF54292 7 108 1.08E-29 T 12-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 VAPA_1c23170 b02e399fb0b817056d86ef78c17b998f 112 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 14 91 3.5E-12 T 12-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 VAPA_1c23170 b02e399fb0b817056d86ef78c17b998f 112 PRINTS PR00355 Adrenodoxin signature 42 52 1.6E-8 T 12-10-2018 IPR001055 Adrenodoxin GO:0009055|GO:0051537 Reactome: R-HSA-1362409|Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 VAPA_1c23170 b02e399fb0b817056d86ef78c17b998f 112 PRINTS PR00355 Adrenodoxin signature 60 74 1.6E-8 T 12-10-2018 IPR001055 Adrenodoxin GO:0009055|GO:0051537 Reactome: R-HSA-1362409|Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 VAPA_1c23170 b02e399fb0b817056d86ef78c17b998f 112 PRINTS PR00355 Adrenodoxin signature 83 91 1.6E-8 T 12-10-2018 IPR001055 Adrenodoxin GO:0009055|GO:0051537 Reactome: R-HSA-1362409|Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 VAPA_1c23170 b02e399fb0b817056d86ef78c17b998f 112 ProSitePatterns PS00814 Adrenodoxin family, iron-sulfur binding region signature. 42 52 - T 12-10-2018 IPR018298 Adrenodoxin, iron-sulphur binding site GO:0009055|GO:0051537 Reactome: R-HSA-1362409|Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 VAPA_1c54530 2e091957c31b85c10bd541f8a9ccd46a 283 SMART SM00062 44 266 3.2E-23 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF VAPA_1c54530 2e091957c31b85c10bd541f8a9ccd46a 283 Gene3D G3DSA:3.40.190.10 131 225 3.5E-38 T 12-10-2018 VAPA_1c54530 2e091957c31b85c10bd541f8a9ccd46a 283 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 45 264 1.2E-31 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF VAPA_1c54530 2e091957c31b85c10bd541f8a9ccd46a 283 Gene3D G3DSA:3.40.190.10 41 258 3.5E-38 T 12-10-2018 VAPA_1c54530 2e091957c31b85c10bd541f8a9ccd46a 283 SUPERFAMILY SSF53850 45 265 8.16E-40 T 12-10-2018 VAPA_1c46320 c956cd1fee9e791226427803b668c8a8 438 Gene3D G3DSA:2.40.30.170 322 374 8.4E-12 T 12-10-2018 VAPA_1c46320 c956cd1fee9e791226427803b668c8a8 438 Gene3D G3DSA:1.10.287.470 96 117 9.6E-8 T 12-10-2018 VAPA_1c46320 c956cd1fee9e791226427803b668c8a8 438 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 358 381 2.8E-31 T 12-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 VAPA_1c46320 c956cd1fee9e791226427803b668c8a8 438 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 402 417 2.8E-31 T 12-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 VAPA_1c46320 c956cd1fee9e791226427803b668c8a8 438 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 301 322 2.8E-31 T 12-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 VAPA_1c46320 c956cd1fee9e791226427803b668c8a8 438 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 417 437 2.8E-31 T 12-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 VAPA_1c46320 c956cd1fee9e791226427803b668c8a8 438 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 334 358 2.8E-31 T 12-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 VAPA_1c46320 c956cd1fee9e791226427803b668c8a8 438 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 74 94 2.8E-31 T 12-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 VAPA_1c46320 c956cd1fee9e791226427803b668c8a8 438 Pfam PF13437 HlyD family secretion protein 289 391 9.7E-15 T 12-10-2018 VAPA_1c46320 c956cd1fee9e791226427803b668c8a8 438 Pfam PF13533 Biotin-lipoyl like 71 95 9.3E-7 T 12-10-2018 IPR039562 Membrane fusion protein, biotin-lipoyl like domain VAPA_1c46320 c956cd1fee9e791226427803b668c8a8 438 Gene3D G3DSA:2.40.50.100 276 321 8.4E-12 T 12-10-2018 VAPA_1c46320 c956cd1fee9e791226427803b668c8a8 438 TIGRFAM TIGR01843 type_I_hlyD: type I secretion membrane fusion protein, HlyD family 26 437 7.9E-100 T 12-10-2018 IPR010129 Type I secretion membrane fusion protein, HlyD family GO:0015031|GO:0016021 VAPA_1c46320 c956cd1fee9e791226427803b668c8a8 438 Gene3D G3DSA:2.40.30.170 50 60 9.6E-8 T 12-10-2018 VAPA_1c46320 c956cd1fee9e791226427803b668c8a8 438 Gene3D G3DSA:1.10.287.470 214 275 8.4E-12 T 12-10-2018 VAPA_1c46320 c956cd1fee9e791226427803b668c8a8 438 Gene3D G3DSA:2.40.50.100 61 95 9.6E-8 T 12-10-2018 VAPA_1c51960 c2d6a2fa818376f67c9526941fb9a73e 262 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 237 259 2.7E-9 T 12-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal VAPA_1c51960 c2d6a2fa818376f67c9526941fb9a73e 262 Gene3D G3DSA:3.40.50.300 8 260 5.2E-60 T 12-10-2018 VAPA_1c51960 c2d6a2fa818376f67c9526941fb9a73e 262 SUPERFAMILY SSF52540 10 259 6.82E-63 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c51960 c2d6a2fa818376f67c9526941fb9a73e 262 SMART SM00382 36 237 5.4E-6 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c51960 c2d6a2fa818376f67c9526941fb9a73e 262 Pfam PF00005 ABC transporter 27 188 7.1E-29 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_2c10570 03c24f6f47ad50dd4b8e02edc2191e71 273 Gene3D G3DSA:3.40.50.1820 3 272 1.9E-83 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_2c10570 03c24f6f47ad50dd4b8e02edc2191e71 273 SUPERFAMILY SSF53474 2 272 5.9E-67 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_2c10570 03c24f6f47ad50dd4b8e02edc2191e71 273 PRINTS PR00111 Alpha/beta hydrolase fold signature 47 62 1.5E-12 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 VAPA_2c10570 03c24f6f47ad50dd4b8e02edc2191e71 273 PRINTS PR00111 Alpha/beta hydrolase fold signature 216 230 1.5E-12 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 VAPA_2c10570 03c24f6f47ad50dd4b8e02edc2191e71 273 PRINTS PR00111 Alpha/beta hydrolase fold signature 91 104 1.5E-12 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 VAPA_2c10570 03c24f6f47ad50dd4b8e02edc2191e71 273 Pfam PF00561 alpha/beta hydrolase fold 22 255 2.6E-27 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 VAPA_2c10570 03c24f6f47ad50dd4b8e02edc2191e71 273 PRINTS PR00412 Epoxide hydrolase signature 214 230 1.4E-6 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 VAPA_2c10570 03c24f6f47ad50dd4b8e02edc2191e71 273 PRINTS PR00412 Epoxide hydrolase signature 47 62 1.4E-6 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 VAPA_2c10570 03c24f6f47ad50dd4b8e02edc2191e71 273 PRINTS PR00412 Epoxide hydrolase signature 27 45 1.4E-6 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 VAPA_1c08860 4f01aaa07851bcd0c836fb4c9948dbf0 328 Gene3D G3DSA:3.40.190.10 192 269 9.8E-7 T 12-10-2018 VAPA_1c08860 4f01aaa07851bcd0c836fb4c9948dbf0 328 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 62 5.0E-16 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c08860 4f01aaa07851bcd0c836fb4c9948dbf0 328 Gene3D G3DSA:3.40.190.10 82 176 5.1E-6 T 12-10-2018 VAPA_1c08860 4f01aaa07851bcd0c836fb4c9948dbf0 328 SUPERFAMILY SSF46785 1 85 3.18E-19 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c08860 4f01aaa07851bcd0c836fb4c9948dbf0 328 Pfam PF03466 LysR substrate binding domain 90 282 1.2E-21 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_1c08860 4f01aaa07851bcd0c836fb4c9948dbf0 328 SUPERFAMILY SSF53850 92 269 8.87E-22 T 12-10-2018 VAPA_1c08860 4f01aaa07851bcd0c836fb4c9948dbf0 328 Gene3D G3DSA:1.10.10.10 1 81 2.0E-20 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c19040 a02050d0d54bd103256bb1d0cc91abff 105 Hamap MF_00720 Primosomal replication protein N [priB]. 11 105 22.79 T 12-10-2018 IPR023646 Primosomal replication protein PriB GO:0003697|GO:0006260|GO:0030894 VAPA_1c19040 a02050d0d54bd103256bb1d0cc91abff 105 SUPERFAMILY SSF50249 11 103 3.94E-16 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold VAPA_1c19040 a02050d0d54bd103256bb1d0cc91abff 105 TIGRFAM TIGR04418 PriB_gamma: primosomal replication protein PriB 12 104 6.2E-29 T 12-10-2018 IPR023646 Primosomal replication protein PriB GO:0003697|GO:0006260|GO:0030894 VAPA_1c19040 a02050d0d54bd103256bb1d0cc91abff 105 Gene3D G3DSA:2.40.50.140 11 105 2.9E-29 T 12-10-2018 VAPA_1c19040 a02050d0d54bd103256bb1d0cc91abff 105 PIRSF PIRSF003135 4 104 1.1E-12 T 12-10-2018 IPR023646 Primosomal replication protein PriB GO:0003697|GO:0006260|GO:0030894 VAPA_1c48230 062f6d7f6e1452e8d9d308eec7909f18 205 Gene3D G3DSA:3.30.1330.60 77 204 1.8E-25 T 12-10-2018 IPR036737 OmpA-like domain superfamily VAPA_1c48230 062f6d7f6e1452e8d9d308eec7909f18 205 SUPERFAMILY SSF103088 99 204 5.23E-26 T 12-10-2018 IPR036737 OmpA-like domain superfamily VAPA_1c48230 062f6d7f6e1452e8d9d308eec7909f18 205 Pfam PF00691 OmpA family 103 198 2.0E-17 T 12-10-2018 IPR006665 OmpA-like domain VAPA_1c48230 062f6d7f6e1452e8d9d308eec7909f18 205 PRINTS PR01021 OMPA domain signature 149 165 1.4E-7 T 12-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 VAPA_1c48230 062f6d7f6e1452e8d9d308eec7909f18 205 PRINTS PR01021 OMPA domain signature 104 126 1.4E-7 T 12-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 VAPA_1c48230 062f6d7f6e1452e8d9d308eec7909f18 205 PRINTS PR01021 OMPA domain signature 134 149 1.4E-7 T 12-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 VAPA_1c04110 b7aeb955bbb7c88c3573994982cfb56d 299 SMART SM00342 197 280 1.3E-21 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 VAPA_1c04110 b7aeb955bbb7c88c3573994982cfb56d 299 Gene3D G3DSA:1.10.10.60 179 229 3.4E-11 T 12-10-2018 VAPA_1c04110 b7aeb955bbb7c88c3573994982cfb56d 299 SUPERFAMILY SSF46689 233 284 1.66E-10 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 VAPA_1c04110 b7aeb955bbb7c88c3573994982cfb56d 299 Gene3D G3DSA:2.60.120.10 6 84 8.0E-6 T 12-10-2018 IPR014710 RmlC-like jelly roll fold VAPA_1c04110 b7aeb955bbb7c88c3573994982cfb56d 299 SUPERFAMILY SSF51215 22 105 5.1E-11 T 12-10-2018 IPR037923 Transcription regulator HTH-like VAPA_1c04110 b7aeb955bbb7c88c3573994982cfb56d 299 SUPERFAMILY SSF46689 181 231 9.86E-8 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 VAPA_1c04110 b7aeb955bbb7c88c3573994982cfb56d 299 Pfam PF12833 Helix-turn-helix domain 203 281 2.4E-20 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 VAPA_1c04110 b7aeb955bbb7c88c3573994982cfb56d 299 Pfam PF02311 AraC-like ligand binding domain 21 138 7.7E-7 T 12-10-2018 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 VAPA_1c04110 b7aeb955bbb7c88c3573994982cfb56d 299 Gene3D G3DSA:1.10.10.60 230 287 4.6E-15 T 12-10-2018 VAPA_1c04110 b7aeb955bbb7c88c3573994982cfb56d 299 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 234 276 - T 12-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 VAPA_1c13170 10e10cc7ee8df46790ab678010ff4b03 503 Pfam PF01970 Tripartite tricarboxylate transporter TctA family 20 441 1.7E-146 T 12-10-2018 IPR002823 Protein of unknown function DUF112, transmembrane VAPA_1c17630 a4df2f81037d761fae69f222caf4a05f 341 Gene3D G3DSA:3.40.190.290 125 334 4.7E-32 T 12-10-2018 VAPA_1c17630 a4df2f81037d761fae69f222caf4a05f 341 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 39 95 2.7E-21 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c17630 a4df2f81037d761fae69f222caf4a05f 341 Pfam PF03466 LysR substrate binding domain 121 324 1.8E-34 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_1c17630 a4df2f81037d761fae69f222caf4a05f 341 SUPERFAMILY SSF53850 124 329 4.15E-35 T 12-10-2018 VAPA_1c17630 a4df2f81037d761fae69f222caf4a05f 341 Gene3D G3DSA:1.10.10.10 37 122 1.0E-23 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c17630 a4df2f81037d761fae69f222caf4a05f 341 SUPERFAMILY SSF46785 39 143 1.24E-22 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c17630 a4df2f81037d761fae69f222caf4a05f 341 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 51 62 5.0E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c17630 a4df2f81037d761fae69f222caf4a05f 341 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 62 72 5.0E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c17630 a4df2f81037d761fae69f222caf4a05f 341 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 72 83 5.0E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c01930 595ae19010efe88d34acee10df64f6b3 339 Pfam PF02423 Ornithine cyclodeaminase/mu-crystallin family 17 321 8.9E-59 T 12-10-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 VAPA_1c01930 595ae19010efe88d34acee10df64f6b3 339 Gene3D G3DSA:3.30.1780.10 15 334 5.2E-83 T 12-10-2018 IPR023401 Ornithine cyclodeaminase, N-terminal Reactome: R-HSA-71064 VAPA_1c01930 595ae19010efe88d34acee10df64f6b3 339 PIRSF PIRSF001439 5 339 1.3E-91 T 12-10-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 VAPA_1c01930 595ae19010efe88d34acee10df64f6b3 339 SUPERFAMILY SSF51735 12 338 5.69E-71 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c01930 595ae19010efe88d34acee10df64f6b3 339 Gene3D G3DSA:3.40.50.720 138 312 5.2E-83 T 12-10-2018 VAPA_1c06790 2a5832ea53f24403b1a95d44b2a8503b 222 SUPERFAMILY SSF52172 1 119 1.99E-30 T 12-10-2018 IPR011006 CheY-like superfamily VAPA_1c06790 2a5832ea53f24403b1a95d44b2a8503b 222 Gene3D G3DSA:3.40.50.2300 1 122 7.9E-33 T 12-10-2018 VAPA_1c06790 2a5832ea53f24403b1a95d44b2a8503b 222 SMART SM00448 1 113 1.2E-32 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_1c06790 2a5832ea53f24403b1a95d44b2a8503b 222 SMART SM00862 146 217 1.0E-22 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 VAPA_1c06790 2a5832ea53f24403b1a95d44b2a8503b 222 Gene3D G3DSA:1.10.10.10 128 221 1.9E-25 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c06790 2a5832ea53f24403b1a95d44b2a8503b 222 SUPERFAMILY SSF46894 126 217 1.62E-23 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 VAPA_1c06790 2a5832ea53f24403b1a95d44b2a8503b 222 Pfam PF00486 Transcriptional regulatory protein, C terminal 148 216 5.9E-19 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 VAPA_1c06790 2a5832ea53f24403b1a95d44b2a8503b 222 Pfam PF00072 Response regulator receiver domain 4 113 3.1E-18 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_1c35770 1258065e65b11d76c12174a46f50d02e 215 Gene3D G3DSA:3.40.50.300 2 215 4.8E-61 T 12-10-2018 VAPA_1c35770 1258065e65b11d76c12174a46f50d02e 215 SMART SM00382 27 212 2.2E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c35770 1258065e65b11d76c12174a46f50d02e 215 SUPERFAMILY SSF52540 3 209 1.16E-60 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c35770 1258065e65b11d76c12174a46f50d02e 215 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_1c35770 1258065e65b11d76c12174a46f50d02e 215 Pfam PF00005 ABC transporter 19 163 4.5E-34 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_2c11120 23eda916ab170b8ed589c7c510bbe741 326 Gene3D G3DSA:3.40.190.10 131 251 1.9E-100 T 12-10-2018 VAPA_2c11120 23eda916ab170b8ed589c7c510bbe741 326 PIRSF PIRSF017082 2 326 1.8E-83 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_2c11120 23eda916ab170b8ed589c7c510bbe741 326 Gene3D G3DSA:3.40.190.150 33 316 1.9E-100 T 12-10-2018 VAPA_2c11120 23eda916ab170b8ed589c7c510bbe741 326 SUPERFAMILY SSF53850 119 288 5.43E-14 T 12-10-2018 VAPA_2c11120 23eda916ab170b8ed589c7c510bbe741 326 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 53 319 8.4E-76 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c54050 9916068a8ce80bd9a54a8c20087da08f 223 Gene3D G3DSA:1.10.10.10 123 222 1.4E-28 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c54050 9916068a8ce80bd9a54a8c20087da08f 223 Pfam PF00486 Transcriptional regulatory protein, C terminal 146 219 4.1E-22 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 VAPA_1c54050 9916068a8ce80bd9a54a8c20087da08f 223 Pfam PF00072 Response regulator receiver domain 3 113 9.8E-26 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_1c54050 9916068a8ce80bd9a54a8c20087da08f 223 SMART SM00448 1 113 1.5E-36 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_1c54050 9916068a8ce80bd9a54a8c20087da08f 223 Gene3D G3DSA:3.40.50.2300 1 122 6.4E-37 T 12-10-2018 VAPA_1c54050 9916068a8ce80bd9a54a8c20087da08f 223 SMART SM00862 146 219 1.7E-24 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 VAPA_1c54050 9916068a8ce80bd9a54a8c20087da08f 223 SUPERFAMILY SSF52172 1 174 1.25E-36 T 12-10-2018 IPR011006 CheY-like superfamily VAPA_1c38280 537d6b1380e2bc09490473a22e83856f 146 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 3 124 1.2E-23 T 12-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain VAPA_1c38280 537d6b1380e2bc09490473a22e83856f 146 ProSitePatterns PS00935 Glyoxalase I signature 2. 70 82 - T 12-10-2018 IPR018146 Glyoxalase I, conserved site GO:0004462|GO:0046872 KEGG: 00620+4.4.1.5|MetaCyc: PWY-5386|Reactome: R-HSA-70268 VAPA_1c38280 537d6b1380e2bc09490473a22e83856f 146 Gene3D G3DSA:3.10.180.10 1 136 2.4E-46 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase VAPA_1c38280 537d6b1380e2bc09490473a22e83856f 146 TIGRFAM TIGR00068 glyox_I: lactoylglutathione lyase 2 131 8.0E-64 T 12-10-2018 IPR004361 Glyoxalase I GO:0004462|GO:0046872 KEGG: 00620+4.4.1.5|MetaCyc: PWY-5386|Reactome: R-HSA-70268 VAPA_1c38280 537d6b1380e2bc09490473a22e83856f 146 SUPERFAMILY SSF54593 1 128 2.82E-34 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase VAPA_1c38280 537d6b1380e2bc09490473a22e83856f 146 ProSitePatterns PS00934 Glyoxalase I signature 1. 5 26 - T 12-10-2018 IPR018146 Glyoxalase I, conserved site GO:0004462|GO:0046872 KEGG: 00620+4.4.1.5|MetaCyc: PWY-5386|Reactome: R-HSA-70268 VAPA_1c42670 3bfa6b7b51a8be5d2cc2a22da95beeee 127 Pfam PF07332 Putative Actinobacterial Holin-X, holin superfamily III 18 117 8.4E-8 T 12-10-2018 IPR009937 Putative Actinobacterial Holin-X, holin superfamily III VAPA_1c20340 1e48287655604ac7c969fde2e0a81ac6 346 Pfam PF12833 Helix-turn-helix domain 255 332 6.3E-19 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 VAPA_1c20340 1e48287655604ac7c969fde2e0a81ac6 346 SMART SM00342 249 331 1.6E-20 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 VAPA_1c20340 1e48287655604ac7c969fde2e0a81ac6 346 SUPERFAMILY SSF46689 285 334 4.87E-10 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 VAPA_1c20340 1e48287655604ac7c969fde2e0a81ac6 346 Pfam PF12625 Arabinose-binding domain of AraC transcription regulator, N-term 24 206 4.0E-45 T 12-10-2018 IPR032687 HTH-type transcriptional regulator AraC-type, N-terminal VAPA_1c20340 1e48287655604ac7c969fde2e0a81ac6 346 Gene3D G3DSA:1.10.10.60 217 339 6.4E-23 T 12-10-2018 VAPA_1c26080 3f6f69f2e187bbbd4f9870ec65188ef1 352 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 142 238 6.2E-19 T 12-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 VAPA_1c26080 3f6f69f2e187bbbd4f9870ec65188ef1 352 Gene3D G3DSA:1.10.3720.10 134 350 2.6E-43 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c26080 3f6f69f2e187bbbd4f9870ec65188ef1 352 SUPERFAMILY SSF161098 142 333 1.19E-34 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c26080 3f6f69f2e187bbbd4f9870ec65188ef1 352 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 160 347 2.3E-18 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 VAPA_1c52400 a3b713c0a284b20a92b8bd333fd8e5bb 121 Gene3D G3DSA:1.10.8.50 1 71 9.9E-27 T 12-10-2018 VAPA_1c52400 a3b713c0a284b20a92b8bd333fd8e5bb 121 SUPERFAMILY SSF46946 2 114 2.65E-44 T 12-10-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 VAPA_1c52400 a3b713c0a284b20a92b8bd333fd8e5bb 121 Hamap MF_01315 30S ribosomal protein S13 [rpsM]. 1 118 27.101 T 12-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VAPA_1c52400 a3b713c0a284b20a92b8bd333fd8e5bb 121 ProSitePatterns PS00646 Ribosomal protein S13 signature. 87 100 - T 12-10-2018 IPR018269 Ribosomal protein S13, conserved site GO:0003723|GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VAPA_1c52400 a3b713c0a284b20a92b8bd333fd8e5bb 121 Gene3D G3DSA:4.10.910.10 72 117 2.8E-25 T 12-10-2018 IPR027437 30s ribosomal protein S13, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VAPA_1c52400 a3b713c0a284b20a92b8bd333fd8e5bb 121 PIRSF PIRSF002134 1 121 8.3E-42 T 12-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VAPA_1c52400 a3b713c0a284b20a92b8bd333fd8e5bb 121 TIGRFAM TIGR03631 uS13_bact: ribosomal protein uS13 3 114 2.0E-52 T 12-10-2018 IPR019980 Ribosomal protein S13, bacterial-type GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 VAPA_1c52400 a3b713c0a284b20a92b8bd333fd8e5bb 121 Pfam PF00416 Ribosomal protein S13/S18 3 61 2.4E-14 T 12-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VAPA_1c52400 a3b713c0a284b20a92b8bd333fd8e5bb 121 Pfam PF00416 Ribosomal protein S13/S18 63 108 4.0E-17 T 12-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VAPA_1c43040 2ec2497604acb5c8488536d79ffacf94 150 Pfam PF13669 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 9 121 2.1E-9 T 12-10-2018 VAPA_1c43040 2ec2497604acb5c8488536d79ffacf94 150 Gene3D G3DSA:3.10.180.10 1 146 5.9E-50 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase VAPA_1c43040 2ec2497604acb5c8488536d79ffacf94 150 SUPERFAMILY SSF54593 2 141 4.13E-27 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase VAPA_1c09110 c12e2a1e8b6c110eb4309953ce5214c4 392 SUPERFAMILY SSF75304 9 390 1.22E-87 T 12-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 VAPA_1c09110 c12e2a1e8b6c110eb4309953ce5214c4 392 ProSitePatterns PS00571 Amidases signature. 109 140 - T 12-10-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 VAPA_1c09110 c12e2a1e8b6c110eb4309953ce5214c4 392 Pfam PF01425 Amidase 20 196 2.8E-51 T 12-10-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 VAPA_1c09110 c12e2a1e8b6c110eb4309953ce5214c4 392 Pfam PF01425 Amidase 292 383 6.2E-6 T 12-10-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 VAPA_1c09110 c12e2a1e8b6c110eb4309953ce5214c4 392 Gene3D G3DSA:3.90.1300.10 15 391 2.6E-91 T 12-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 VAPA_2c10530 33022312297e729fbd910ce93509a02b 481 SMART SM01060 12 395 4.4E-238 T 12-10-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 VAPA_2c10530 33022312297e729fbd910ce93509a02b 481 PIRSF PIRSF038928 1 481 1.0E-189 T 12-10-2018 IPR024711 Catalase, mono-functional, haem-containing, clades 1 and 3 GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 VAPA_2c10530 33022312297e729fbd910ce93509a02b 481 SUPERFAMILY SSF56634 5 480 1.28E-185 T 12-10-2018 IPR020835 Catalase superfamily GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 VAPA_2c10530 33022312297e729fbd910ce93509a02b 481 PRINTS PR00067 Catalase signature 87 105 1.8E-59 T 12-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 VAPA_2c10530 33022312297e729fbd910ce93509a02b 481 PRINTS PR00067 Catalase signature 324 350 1.8E-59 T 12-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 VAPA_2c10530 33022312297e729fbd910ce93509a02b 481 PRINTS PR00067 Catalase signature 127 145 1.8E-59 T 12-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 VAPA_2c10530 33022312297e729fbd910ce93509a02b 481 PRINTS PR00067 Catalase signature 108 125 1.8E-59 T 12-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 VAPA_2c10530 33022312297e729fbd910ce93509a02b 481 PRINTS PR00067 Catalase signature 25 48 1.8E-59 T 12-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 VAPA_2c10530 33022312297e729fbd910ce93509a02b 481 PRINTS PR00067 Catalase signature 292 319 1.8E-59 T 12-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 VAPA_2c10530 33022312297e729fbd910ce93509a02b 481 Pfam PF00199 Catalase 12 392 1.0E-161 T 12-10-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 VAPA_2c10530 33022312297e729fbd910ce93509a02b 481 Gene3D G3DSA:2.40.180.10 8 481 2.1E-191 T 12-10-2018 IPR037060 Catalase core domain superfamily GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 VAPA_2c10530 33022312297e729fbd910ce93509a02b 481 Pfam PF06628 Catalase-related immune-responsive 423 479 9.0E-17 T 12-10-2018 IPR010582 Catalase immune-responsive domain KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 VAPA_1c42530 f1b6fce7cfa4b0872caf30d21404dc02 292 Pfam PF01729 Quinolinate phosphoribosyl transferase, C-terminal domain 118 288 5.4E-56 T 12-10-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 Reactome: R-HSA-196807 VAPA_1c42530 f1b6fce7cfa4b0872caf30d21404dc02 292 SUPERFAMILY SSF51690 118 289 1.84E-55 T 12-10-2018 IPR036068 Nicotinate phosphoribosyltransferase-like, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 VAPA_1c42530 f1b6fce7cfa4b0872caf30d21404dc02 292 SUPERFAMILY SSF54675 16 116 1.47E-29 T 12-10-2018 VAPA_1c42530 f1b6fce7cfa4b0872caf30d21404dc02 292 Gene3D G3DSA:3.20.20.70 128 280 3.2E-103 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 VAPA_1c42530 f1b6fce7cfa4b0872caf30d21404dc02 292 TIGRFAM TIGR00078 nadC: nicotinate-nucleotide diphosphorylase (carboxylating) 21 289 7.0E-91 T 12-10-2018 IPR004393 Nicotinate-nucleotide pyrophosphorylase GO:0004514|GO:0019363 KEGG: 00760+2.4.2.19|MetaCyc: PWY-5316|MetaCyc: PWY-5653|MetaCyc: PWY-7342|Reactome: R-HSA-196807 VAPA_1c42530 f1b6fce7cfa4b0872caf30d21404dc02 292 Gene3D G3DSA:3.90.1170.20 21 287 3.2E-103 T 12-10-2018 IPR037128 Quinolinate phosphoribosyl transferase, N-terminal domain superfamily GO:0016763 Reactome: R-HSA-196807 VAPA_1c42530 f1b6fce7cfa4b0872caf30d21404dc02 292 Pfam PF02749 Quinolinate phosphoribosyl transferase, N-terminal domain 28 116 2.1E-25 T 12-10-2018 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 VAPA_1c42530 f1b6fce7cfa4b0872caf30d21404dc02 292 PIRSF PIRSF006250 11 291 5.8E-91 T 12-10-2018 IPR027277 Nicotinate-nucleotide pyrophosphorylase/Putative pyrophosphorylase ModD Reactome: R-HSA-196807 VAPA_1c42760 6078933bd528db9e598387ba8deb5d8d 157 Gene3D G3DSA:3.90.79.10 4 151 1.4E-29 T 12-10-2018 VAPA_1c42760 6078933bd528db9e598387ba8deb5d8d 157 SUPERFAMILY SSF55811 8 155 2.03E-24 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 VAPA_1c42760 6078933bd528db9e598387ba8deb5d8d 157 Pfam PF00293 NUDIX domain 12 148 3.4E-13 T 12-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 VAPA_1c42760 6078933bd528db9e598387ba8deb5d8d 157 PRINTS PR01404 DATP pyrophosphohydrolase signature 24 45 2.8E-5 T 12-10-2018 IPR003564 Dihydroneopterin triphosphate diphosphatase GO:0008828|GO:0019177|GO:0046656 KEGG: 00790+3.6.1.67|MetaCyc: PWY-6147 VAPA_1c42760 6078933bd528db9e598387ba8deb5d8d 157 PRINTS PR01404 DATP pyrophosphohydrolase signature 136 149 2.8E-5 T 12-10-2018 IPR003564 Dihydroneopterin triphosphate diphosphatase GO:0008828|GO:0019177|GO:0046656 KEGG: 00790+3.6.1.67|MetaCyc: PWY-6147 VAPA_1c28720 1c5f2de194f6f1e364411552ad0f2093 799 SUPERFAMILY SSF82866 246 405 1.1E-14 T 12-10-2018 VAPA_1c28720 1c5f2de194f6f1e364411552ad0f2093 799 SUPERFAMILY SSF82866 635 788 2.75E-16 T 12-10-2018 VAPA_1c32330 4ab523a4f182d94743123832612db7c2 1131 SMART SM00448 922 1034 2.0E-23 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_1c32330 4ab523a4f182d94743123832612db7c2 1131 SMART SM00388 674 739 1.1E-22 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 VAPA_1c32330 4ab523a4f182d94743123832612db7c2 1131 Pfam PF00072 Response regulator receiver domain 925 1034 9.7E-18 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_1c32330 4ab523a4f182d94743123832612db7c2 1131 SUPERFAMILY SSF47384 660 740 2.55E-20 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 VAPA_1c32330 4ab523a4f182d94743123832612db7c2 1131 SUPERFAMILY SSF55874 729 893 3.01E-39 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_1c32330 4ab523a4f182d94743123832612db7c2 1131 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 787 893 8.2E-22 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase VAPA_1c32330 4ab523a4f182d94743123832612db7c2 1131 Gene3D G3DSA:1.10.287.130 636 737 6.4E-25 T 12-10-2018 VAPA_1c32330 4ab523a4f182d94743123832612db7c2 1131 Pfam PF00512 His Kinase A (phospho-acceptor) domain 674 739 2.1E-16 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 VAPA_1c32330 4ab523a4f182d94743123832612db7c2 1131 Gene3D G3DSA:3.40.50.12740 922 1118 1.7E-30 T 12-10-2018 VAPA_1c32330 4ab523a4f182d94743123832612db7c2 1131 Gene3D G3DSA:3.30.565.10 738 898 4.0E-40 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_1c32330 4ab523a4f182d94743123832612db7c2 1131 SUPERFAMILY SSF52172 921 1045 4.41E-31 T 12-10-2018 IPR011006 CheY-like superfamily VAPA_1c32330 4ab523a4f182d94743123832612db7c2 1131 Gene3D G3DSA:1.10.4160.10 20 473 3.4E-15 T 12-10-2018 IPR038271 Purine-cytosine permease superfamily VAPA_1c32330 4ab523a4f182d94743123832612db7c2 1131 PRINTS PR00344 Bacterial sensor protein C-terminal signature 857 875 1.7E-6 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c32330 4ab523a4f182d94743123832612db7c2 1131 PRINTS PR00344 Bacterial sensor protein C-terminal signature 822 836 1.7E-6 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c32330 4ab523a4f182d94743123832612db7c2 1131 PRINTS PR00344 Bacterial sensor protein C-terminal signature 840 850 1.7E-6 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c32330 4ab523a4f182d94743123832612db7c2 1131 SMART SM00387 786 897 5.9E-30 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase VAPA_2c09370 8751b61f630f4758e9274543dad1866c 462 TIGRFAM TIGR01424 gluta_reduc_2: glutathione-disulfide reductase 4 450 9.6E-217 T 12-10-2018 IPR006324 Glutathione-disulphide reductase GO:0004362|GO:0006749|GO:0050660|GO:0050661|GO:0055114 KEGG: 00480+1.8.1.7|MetaCyc: PWY-4081 VAPA_2c09370 8751b61f630f4758e9274543dad1866c 462 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 341 449 2.7E-33 T 12-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 VAPA_2c09370 8751b61f630f4758e9274543dad1866c 462 SUPERFAMILY SSF51905 3 362 2.83E-51 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_2c09370 8751b61f630f4758e9274543dad1866c 462 Gene3D G3DSA:3.50.50.60 6 321 1.5E-113 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_2c09370 8751b61f630f4758e9274543dad1866c 462 PIRSF PIRSF000350 1 452 4.7E-79 T 12-10-2018 IPR001100 Pyridine nucleotide-disulphide oxidoreductase, class I GO:0009055|GO:0016491 VAPA_2c09370 8751b61f630f4758e9274543dad1866c 462 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 321 3.8E-64 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 VAPA_2c09370 8751b61f630f4758e9274543dad1866c 462 Gene3D G3DSA:3.50.50.60 146 264 1.5E-113 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_2c09370 8751b61f630f4758e9274543dad1866c 462 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 134 152 2.3E-32 T 12-10-2018 VAPA_2c09370 8751b61f630f4758e9274543dad1866c 462 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 172 190 2.3E-32 T 12-10-2018 VAPA_2c09370 8751b61f630f4758e9274543dad1866c 462 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 257 273 2.3E-32 T 12-10-2018 VAPA_2c09370 8751b61f630f4758e9274543dad1866c 462 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 8 27 2.3E-32 T 12-10-2018 VAPA_2c09370 8751b61f630f4758e9274543dad1866c 462 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 286 308 2.3E-32 T 12-10-2018 VAPA_2c09370 8751b61f630f4758e9274543dad1866c 462 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 40 50 - T 12-10-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 VAPA_2c09370 8751b61f630f4758e9274543dad1866c 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 39 54 4.0E-67 T 12-10-2018 VAPA_2c09370 8751b61f630f4758e9274543dad1866c 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 137 146 4.0E-67 T 12-10-2018 VAPA_2c09370 8751b61f630f4758e9274543dad1866c 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 172 197 4.0E-67 T 12-10-2018 VAPA_2c09370 8751b61f630f4758e9274543dad1866c 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 258 272 4.0E-67 T 12-10-2018 VAPA_2c09370 8751b61f630f4758e9274543dad1866c 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 301 308 4.0E-67 T 12-10-2018 VAPA_2c09370 8751b61f630f4758e9274543dad1866c 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 7 29 4.0E-67 T 12-10-2018 VAPA_2c09370 8751b61f630f4758e9274543dad1866c 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 424 444 4.0E-67 T 12-10-2018 VAPA_2c09370 8751b61f630f4758e9274543dad1866c 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 337 358 4.0E-67 T 12-10-2018 VAPA_2c09370 8751b61f630f4758e9274543dad1866c 462 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 402 417 4.0E-67 T 12-10-2018 VAPA_2c09370 8751b61f630f4758e9274543dad1866c 462 Gene3D G3DSA:3.30.390.30 340 462 3.5E-47 T 12-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 VAPA_2c09370 8751b61f630f4758e9274543dad1866c 462 SUPERFAMILY SSF55424 337 454 1.44E-34 T 12-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 VAPA_1c38810 74a8f2fb006e154af13904fb0e0bf066 733 Gene3D G3DSA:2.40.170.20 206 733 2.9E-87 T 12-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily VAPA_1c38810 74a8f2fb006e154af13904fb0e0bf066 733 SUPERFAMILY SSF56935 61 733 1.43E-115 T 12-10-2018 VAPA_1c38810 74a8f2fb006e154af13904fb0e0bf066 733 ProSitePatterns PS01156 TonB-dependent receptor proteins signature 2. 716 733 - T 12-10-2018 IPR010917 TonB-dependent receptor, conserved site VAPA_1c38810 74a8f2fb006e154af13904fb0e0bf066 733 Pfam PF07715 TonB-dependent Receptor Plug Domain 94 195 1.4E-12 T 12-10-2018 IPR012910 TonB-dependent receptor, plug domain VAPA_1c38810 74a8f2fb006e154af13904fb0e0bf066 733 Gene3D G3DSA:2.170.130.10 63 205 5.8E-20 T 12-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily VAPA_1c38810 74a8f2fb006e154af13904fb0e0bf066 733 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 96 733 9.0E-99 T 12-10-2018 IPR010105 TonB-dependent siderophore receptor GO:0005506|GO:0015891|GO:0038023 VAPA_1c38810 74a8f2fb006e154af13904fb0e0bf066 733 Pfam PF00593 TonB dependent receptor 321 730 3.6E-44 T 12-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel VAPA_1c32130 b8c83b7883fe5503ee4aaa23c5f3d898 326 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 50 320 8.7E-90 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c32130 b8c83b7883fe5503ee4aaa23c5f3d898 326 SUPERFAMILY SSF53850 113 287 2.17E-15 T 12-10-2018 VAPA_1c32130 b8c83b7883fe5503ee4aaa23c5f3d898 326 Gene3D G3DSA:3.40.190.10 128 251 5.9E-117 T 12-10-2018 VAPA_1c32130 b8c83b7883fe5503ee4aaa23c5f3d898 326 PIRSF PIRSF017082 1 326 9.7E-85 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c32130 b8c83b7883fe5503ee4aaa23c5f3d898 326 Gene3D G3DSA:3.40.190.150 31 316 5.9E-117 T 12-10-2018 VAPA_1c17470 667d4af99b3681eed7e8df0d3400a6f4 499 Pfam PF06745 KaiC 257 477 6.4E-28 T 12-10-2018 IPR014774 KaiC-like domain VAPA_1c17470 667d4af99b3681eed7e8df0d3400a6f4 499 Pfam PF06745 KaiC 17 242 3.4E-39 T 12-10-2018 IPR014774 KaiC-like domain VAPA_1c17470 667d4af99b3681eed7e8df0d3400a6f4 499 SMART SM00382 274 438 0.31 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c17470 667d4af99b3681eed7e8df0d3400a6f4 499 SMART SM00382 33 219 0.015 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c17470 667d4af99b3681eed7e8df0d3400a6f4 499 SUPERFAMILY SSF52540 17 250 3.55E-34 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c17470 667d4af99b3681eed7e8df0d3400a6f4 499 SUPERFAMILY SSF52540 255 488 2.17E-42 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c17470 667d4af99b3681eed7e8df0d3400a6f4 499 PIRSF PIRSF039117 1 495 1.0E-122 T 12-10-2018 IPR030665 Circadian clock protein kinase KaiC KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1 VAPA_1c17470 667d4af99b3681eed7e8df0d3400a6f4 499 Gene3D G3DSA:3.40.50.300 251 493 2.5E-53 T 12-10-2018 VAPA_1c17470 667d4af99b3681eed7e8df0d3400a6f4 499 Gene3D G3DSA:3.40.50.300 11 250 1.1E-47 T 12-10-2018 VAPA_1c17130 bd4474b8619d4b56905e358e34c2f962 377 Gene3D G3DSA:3.90.1150.10 267 377 3.0E-41 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 VAPA_1c17130 bd4474b8619d4b56905e358e34c2f962 377 TIGRFAM TIGR01364 serC_1: phosphoserine transaminase 14 376 3.1E-144 T 12-10-2018 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 VAPA_1c17130 bd4474b8619d4b56905e358e34c2f962 377 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 199 218 - T 12-10-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site VAPA_1c17130 bd4474b8619d4b56905e358e34c2f962 377 Hamap MF_00160 Phosphoserine aminotransferase [serC]. 11 376 47.153 T 12-10-2018 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 VAPA_1c17130 bd4474b8619d4b56905e358e34c2f962 377 SUPERFAMILY SSF53383 12 374 3.61E-105 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase VAPA_1c17130 bd4474b8619d4b56905e358e34c2f962 377 Gene3D G3DSA:3.40.640.10 26 266 5.8E-85 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 VAPA_1c17130 bd4474b8619d4b56905e358e34c2f962 377 Pfam PF00266 Aminotransferase class-V 14 365 7.4E-47 T 12-10-2018 IPR000192 Aminotransferase class V domain VAPA_1c17130 bd4474b8619d4b56905e358e34c2f962 377 PIRSF PIRSF000525 7 377 1.5E-142 T 12-10-2018 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 VAPA_1c49640 017fb6b08586b0a3387cb77fe5d6c18e 211 SUPERFAMILY SSF46689 4 65 2.64E-14 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 VAPA_1c49640 017fb6b08586b0a3387cb77fe5d6c18e 211 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 11 24 3.5E-7 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 VAPA_1c49640 017fb6b08586b0a3387cb77fe5d6c18e 211 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 32 55 3.5E-7 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 VAPA_1c49640 017fb6b08586b0a3387cb77fe5d6c18e 211 Gene3D G3DSA:1.10.357.10 3 210 9.3E-52 T 12-10-2018 VAPA_1c49640 017fb6b08586b0a3387cb77fe5d6c18e 211 Pfam PF00440 Bacterial regulatory proteins, tetR family 11 53 6.1E-11 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 VAPA_1c49640 017fb6b08586b0a3387cb77fe5d6c18e 211 Pfam PF13972 Bacterial transcriptional repressor 64 201 1.7E-25 T 12-10-2018 IPR025722 Bacterial transcriptional repressor TetR VAPA_1c19460 053d5d6f7a3bcf381cf8801fb136034b 229 Gene3D G3DSA:3.40.30.10 15 92 9.4E-44 T 12-10-2018 VAPA_1c19460 053d5d6f7a3bcf381cf8801fb136034b 229 SUPERFAMILY SSF47616 92 215 1.6E-10 T 12-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily VAPA_1c19460 053d5d6f7a3bcf381cf8801fb136034b 229 Gene3D G3DSA:1.20.1050.10 93 207 9.4E-44 T 12-10-2018 VAPA_1c19460 053d5d6f7a3bcf381cf8801fb136034b 229 Pfam PF13417 Glutathione S-transferase, N-terminal domain 15 90 2.9E-9 T 12-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 VAPA_1c19460 053d5d6f7a3bcf381cf8801fb136034b 229 SUPERFAMILY SSF52833 10 95 2.85E-17 T 12-10-2018 IPR036249 Thioredoxin-like superfamily VAPA_1c20570 9412fdf1e52266666e4af4dbeab5371c 774 Pfam PF00577 Outer membrane usher protein 184 676 1.5E-30 T 12-10-2018 IPR000015 Outer membrane usher protein GO:0009297|GO:0015473|GO:0016020 VAPA_1c20570 9412fdf1e52266666e4af4dbeab5371c 774 Gene3D G3DSA:2.60.40.2070 689 768 2.1E-5 T 12-10-2018 VAPA_1c20570 9412fdf1e52266666e4af4dbeab5371c 774 Gene3D G3DSA:2.60.40.2610 596 685 3.2E-12 T 12-10-2018 VAPA_1c20570 9412fdf1e52266666e4af4dbeab5371c 774 Pfam PF13953 PapC C-terminal domain 694 752 1.8E-10 T 12-10-2018 IPR025949 PapC-like, C-terminal domain VAPA_1c20570 9412fdf1e52266666e4af4dbeab5371c 774 Gene3D G3DSA:2.60.40.3110 224 313 7.0E-9 T 12-10-2018 VAPA_1c51670 f57a91542a02f0827d2d2ac95d084e1b 347 Pfam PF13343 Bacterial extracellular solute-binding protein 79 322 1.7E-33 T 12-10-2018 VAPA_1c51670 f57a91542a02f0827d2d2ac95d084e1b 347 SUPERFAMILY SSF53850 28 340 1.49E-68 T 12-10-2018 VAPA_1c51670 f57a91542a02f0827d2d2ac95d084e1b 347 PIRSF PIRSF002825 4 343 7.1E-64 T 12-10-2018 IPR026045 Ferric binding protein VAPA_1c51670 f57a91542a02f0827d2d2ac95d084e1b 347 Gene3D G3DSA:3.40.190.10 137 324 1.7E-93 T 12-10-2018 VAPA_1c51670 f57a91542a02f0827d2d2ac95d084e1b 347 Gene3D G3DSA:3.40.190.10 37 309 1.7E-93 T 12-10-2018 VAPA_1c03990 a84b97d210fa268ebeb381b731f423d6 400 PIRSF PIRSF005962 1 396 6.6E-127 T 12-10-2018 IPR017439 Amidohydrolase GO:0016787 VAPA_1c03990 a84b97d210fa268ebeb381b731f423d6 400 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 16 361 5.7E-110 T 12-10-2018 IPR017439 Amidohydrolase GO:0016787 VAPA_1c03990 a84b97d210fa268ebeb381b731f423d6 400 SUPERFAMILY SSF53187 9 394 2.29E-85 T 12-10-2018 VAPA_1c03990 a84b97d210fa268ebeb381b731f423d6 400 SUPERFAMILY SSF55031 185 296 5.76E-32 T 12-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain VAPA_1c03990 a84b97d210fa268ebeb381b731f423d6 400 Pfam PF01546 Peptidase family M20/M25/M40 73 355 3.5E-34 T 12-10-2018 IPR002933 Peptidase M20 GO:0016787 VAPA_1c03990 a84b97d210fa268ebeb381b731f423d6 400 Gene3D G3DSA:3.30.70.360 181 295 3.4E-136 T 12-10-2018 VAPA_1c03990 a84b97d210fa268ebeb381b731f423d6 400 Pfam PF07687 Peptidase dimerisation domain 187 282 2.1E-12 T 12-10-2018 IPR011650 Peptidase M20, dimerisation domain VAPA_1c03990 a84b97d210fa268ebeb381b731f423d6 400 Gene3D G3DSA:3.40.630.10 16 377 3.4E-136 T 12-10-2018 VAPA_1c31460 550a92267e4ae16c50784ba2c9aa5786 335 Hamap MF_00486 Methenyltetrahydromethanopterin cyclohydrolase [mch]. 1 335 136.826 T 12-10-2018 IPR003209 Methenyltetrahydromethanopterin cyclohydrolase GO:0006730|GO:0018759 KEGG: 00680+3.5.4.27|MetaCyc: PWY-1723|MetaCyc: PWY-7784 VAPA_1c31460 550a92267e4ae16c50784ba2c9aa5786 335 Pfam PF02289 Cyclohydrolase (MCH) 14 329 2.7E-123 T 12-10-2018 IPR003209 Methenyltetrahydromethanopterin cyclohydrolase GO:0006730|GO:0018759 KEGG: 00680+3.5.4.27|MetaCyc: PWY-1723|MetaCyc: PWY-7784 VAPA_1c31460 550a92267e4ae16c50784ba2c9aa5786 335 TIGRFAM TIGR03120 one_C_mch: methenyltetrahydromethanopterin cyclohydrolase 14 329 2.0E-112 T 12-10-2018 IPR003209 Methenyltetrahydromethanopterin cyclohydrolase GO:0006730|GO:0018759 KEGG: 00680+3.5.4.27|MetaCyc: PWY-1723|MetaCyc: PWY-7784 VAPA_1c31460 550a92267e4ae16c50784ba2c9aa5786 335 Gene3D G3DSA:3.30.1030.10 56 329 5.6E-113 T 12-10-2018 VAPA_1c31460 550a92267e4ae16c50784ba2c9aa5786 335 Gene3D G3DSA:3.10.340.11 14 186 5.6E-113 T 12-10-2018 VAPA_1c31460 550a92267e4ae16c50784ba2c9aa5786 335 SUPERFAMILY SSF56199 13 329 2.88E-115 T 12-10-2018 VAPA_1c52320 6b2d2d99d0082a98a7fdc90a52964a4b 397 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 133 226 2.0E-20 T 12-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 VAPA_1c52320 6b2d2d99d0082a98a7fdc90a52964a4b 397 Gene3D G3DSA:2.40.110.10 132 243 4.3E-40 T 12-10-2018 VAPA_1c52320 6b2d2d99d0082a98a7fdc90a52964a4b 397 SUPERFAMILY SSF47203 236 396 3.38E-46 T 12-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 VAPA_1c52320 6b2d2d99d0082a98a7fdc90a52964a4b 397 SUPERFAMILY SSF56645 18 249 6.81E-58 T 12-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 VAPA_1c52320 6b2d2d99d0082a98a7fdc90a52964a4b 397 PIRSF PIRSF016578 241 395 2.3E-14 T 12-10-2018 VAPA_1c52320 6b2d2d99d0082a98a7fdc90a52964a4b 397 PIRSF PIRSF016578 113 206 0.0033 T 12-10-2018 VAPA_1c52320 6b2d2d99d0082a98a7fdc90a52964a4b 397 PIRSF PIRSF016578 6 93 0.26 T 12-10-2018 VAPA_1c52320 6b2d2d99d0082a98a7fdc90a52964a4b 397 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 238 394 3.5E-41 T 12-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 VAPA_1c52320 6b2d2d99d0082a98a7fdc90a52964a4b 397 Gene3D G3DSA:1.10.540.10 15 131 4.2E-21 T 12-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 VAPA_1c52320 6b2d2d99d0082a98a7fdc90a52964a4b 397 Gene3D G3DSA:1.20.140.10 244 395 1.3E-43 T 12-10-2018 VAPA_1c52320 6b2d2d99d0082a98a7fdc90a52964a4b 397 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 135 147 - T 12-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 VAPA_1c52320 6b2d2d99d0082a98a7fdc90a52964a4b 397 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 20 129 6.9E-11 T 12-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 VAPA_1c19650 4dea3ccfcab10e8f6b8b3bcbc51a2bfc 635 Gene3D G3DSA:3.30.980.10 69 221 3.7E-60 T 12-10-2018 VAPA_1c19650 4dea3ccfcab10e8f6b8b3bcbc51a2bfc 635 Gene3D G3DSA:3.10.20.30 1 63 8.0E-23 T 12-10-2018 IPR012675 Beta-grasp domain superfamily VAPA_1c19650 4dea3ccfcab10e8f6b8b3bcbc51a2bfc 635 SUPERFAMILY SSF55186 64 240 4.97E-64 T 12-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 VAPA_1c19650 4dea3ccfcab10e8f6b8b3bcbc51a2bfc 635 SUPERFAMILY SSF81271 2 61 1.63E-14 T 12-10-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 VAPA_1c19650 4dea3ccfcab10e8f6b8b3bcbc51a2bfc 635 Gene3D G3DSA:3.40.50.800 531 635 3.3E-31 T 12-10-2018 IPR036621 Anticodon-binding domain superfamily VAPA_1c19650 4dea3ccfcab10e8f6b8b3bcbc51a2bfc 635 Gene3D G3DSA:3.30.930.10 222 530 1.6E-124 T 12-10-2018 VAPA_1c19650 4dea3ccfcab10e8f6b8b3bcbc51a2bfc 635 PRINTS PR01047 Threonyl-tRNA synthetase signature 361 384 7.5E-53 T 12-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 VAPA_1c19650 4dea3ccfcab10e8f6b8b3bcbc51a2bfc 635 PRINTS PR01047 Threonyl-tRNA synthetase signature 506 519 7.5E-53 T 12-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 VAPA_1c19650 4dea3ccfcab10e8f6b8b3bcbc51a2bfc 635 PRINTS PR01047 Threonyl-tRNA synthetase signature 533 545 7.5E-53 T 12-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 VAPA_1c19650 4dea3ccfcab10e8f6b8b3bcbc51a2bfc 635 PRINTS PR01047 Threonyl-tRNA synthetase signature 328 356 7.5E-53 T 12-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 VAPA_1c19650 4dea3ccfcab10e8f6b8b3bcbc51a2bfc 635 PRINTS PR01047 Threonyl-tRNA synthetase signature 463 491 7.5E-53 T 12-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 VAPA_1c19650 4dea3ccfcab10e8f6b8b3bcbc51a2bfc 635 Pfam PF02824 TGS domain 2 61 5.8E-9 T 12-10-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 VAPA_1c19650 4dea3ccfcab10e8f6b8b3bcbc51a2bfc 635 SUPERFAMILY SSF55681 242 525 1.63E-95 T 12-10-2018 VAPA_1c19650 4dea3ccfcab10e8f6b8b3bcbc51a2bfc 635 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 173 218 7.8E-14 T 12-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 VAPA_1c19650 4dea3ccfcab10e8f6b8b3bcbc51a2bfc 635 Gene3D G3DSA:3.30.54.20 130 186 3.7E-60 T 12-10-2018 VAPA_1c19650 4dea3ccfcab10e8f6b8b3bcbc51a2bfc 635 SMART SM00863 169 218 1.3E-19 T 12-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 VAPA_1c19650 4dea3ccfcab10e8f6b8b3bcbc51a2bfc 635 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 318 528 7.0E-41 T 12-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 VAPA_1c19650 4dea3ccfcab10e8f6b8b3bcbc51a2bfc 635 Hamap MF_00184 Threonine--tRNA ligase [thrS]. 66 633 34.048 T 12-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 VAPA_1c19650 4dea3ccfcab10e8f6b8b3bcbc51a2bfc 635 TIGRFAM TIGR00418 thrS: threonine--tRNA ligase 72 630 6.2E-219 T 12-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 VAPA_1c19650 4dea3ccfcab10e8f6b8b3bcbc51a2bfc 635 Pfam PF03129 Anticodon binding domain 540 627 2.9E-20 T 12-10-2018 IPR004154 Anticodon-binding VAPA_1c19650 4dea3ccfcab10e8f6b8b3bcbc51a2bfc 635 SUPERFAMILY SSF52954 529 632 3.78E-30 T 12-10-2018 VAPA_1c26750 6b9686da75da33510a64bbe04243bc96 261 ProSitePatterns PS00211 ABC transporters family signature. 155 169 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_1c26750 6b9686da75da33510a64bbe04243bc96 261 Gene3D G3DSA:3.40.50.300 19 258 3.0E-77 T 12-10-2018 VAPA_1c26750 6b9686da75da33510a64bbe04243bc96 261 SMART SM00382 44 227 2.0E-14 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c26750 6b9686da75da33510a64bbe04243bc96 261 Pfam PF00005 ABC transporter 35 183 4.6E-33 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c26750 6b9686da75da33510a64bbe04243bc96 261 SUPERFAMILY SSF52540 20 253 9.96E-78 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c26750 6b9686da75da33510a64bbe04243bc96 261 PIRSF PIRSF039085 16 258 2.3E-107 T 12-10-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 VAPA_1c14830 fc159d9d673582a72384c824029de623 317 TIGRFAM TIGR00128 fabD: malonyl CoA-acyl carrier protein transacylase 3 296 5.1E-94 T 12-10-2018 IPR004410 Malonyl CoA-acyl carrier protein transacylase, FabD-type GO:0004314 KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 VAPA_1c14830 fc159d9d673582a72384c824029de623 317 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 7 314 3.6E-33 T 12-10-2018 IPR020801 Polyketide synthase, acyl transferase domain VAPA_1c14830 fc159d9d673582a72384c824029de623 317 Pfam PF00698 Acyl transferase domain 6 286 5.3E-32 T 12-10-2018 IPR014043 Acyl transferase VAPA_1c14830 fc159d9d673582a72384c824029de623 317 Gene3D G3DSA:3.30.70.250 124 202 1.3E-91 T 12-10-2018 VAPA_1c14830 fc159d9d673582a72384c824029de623 317 SUPERFAMILY SSF55048 129 202 5.75E-13 T 12-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding VAPA_1c14830 fc159d9d673582a72384c824029de623 317 Gene3D G3DSA:3.40.366.10 5 289 1.3E-91 T 12-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 VAPA_1c14830 fc159d9d673582a72384c824029de623 317 SUPERFAMILY SSF52151 4 314 2.62E-74 T 12-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase VAPA_1c14830 fc159d9d673582a72384c824029de623 317 PIRSF PIRSF000446 1 316 4.2E-98 T 12-10-2018 IPR024925 Malonyl CoA-acyl carrier protein transacylase KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 VAPA_1c22320 85d775309ff6890f88cf3f27c01f310c 417 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 234 259 1.3E-12 T 12-10-2018 VAPA_1c22320 85d775309ff6890f88cf3f27c01f310c 417 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 360 367 1.3E-12 T 12-10-2018 VAPA_1c22320 85d775309ff6890f88cf3f27c01f310c 417 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 92 114 1.3E-12 T 12-10-2018 VAPA_1c22320 85d775309ff6890f88cf3f27c01f310c 417 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 320 334 1.3E-12 T 12-10-2018 VAPA_1c22320 85d775309ff6890f88cf3f27c01f310c 417 PRINTS PR00163 Rubredoxin signature 49 65 8.1E-9 T 12-10-2018 IPR024935 Rubredoxin domain GO:0005506 VAPA_1c22320 85d775309ff6890f88cf3f27c01f310c 417 PRINTS PR00163 Rubredoxin signature 19 35 8.1E-9 T 12-10-2018 IPR024935 Rubredoxin domain GO:0005506 VAPA_1c22320 85d775309ff6890f88cf3f27c01f310c 417 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 188 206 3.8E-16 T 12-10-2018 VAPA_1c22320 85d775309ff6890f88cf3f27c01f310c 417 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 345 367 3.8E-16 T 12-10-2018 VAPA_1c22320 85d775309ff6890f88cf3f27c01f310c 417 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 93 112 3.8E-16 T 12-10-2018 VAPA_1c22320 85d775309ff6890f88cf3f27c01f310c 417 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 234 252 3.8E-16 T 12-10-2018 VAPA_1c22320 85d775309ff6890f88cf3f27c01f310c 417 SUPERFAMILY SSF51905 88 393 9.67E-30 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c22320 85d775309ff6890f88cf3f27c01f310c 417 SUPERFAMILY SSF57802 17 68 3.37E-20 T 12-10-2018 VAPA_1c22320 85d775309ff6890f88cf3f27c01f310c 417 Pfam PF00301 Rubredoxin 19 65 1.1E-21 T 12-10-2018 IPR024935 Rubredoxin domain GO:0005506 VAPA_1c22320 85d775309ff6890f88cf3f27c01f310c 417 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 93 371 6.0E-38 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 VAPA_1c22320 85d775309ff6890f88cf3f27c01f310c 417 Gene3D G3DSA:2.20.28.10 10 71 5.4E-25 T 12-10-2018 VAPA_1c22320 85d775309ff6890f88cf3f27c01f310c 417 ProSitePatterns PS00202 Rubredoxin signature. 49 59 - T 12-10-2018 IPR018527 Rubredoxin, iron-binding site GO:0046872 VAPA_1c22320 85d775309ff6890f88cf3f27c01f310c 417 Gene3D G3DSA:3.50.50.60 94 367 1.1E-56 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c22320 85d775309ff6890f88cf3f27c01f310c 417 Gene3D G3DSA:3.50.50.60 196 331 1.1E-56 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c07770 6d9ffb93f55c0e24624d4a52b3727d7f 704 Gene3D G3DSA:1.10.486.10 384 564 1.4E-100 T 12-10-2018 VAPA_1c07770 6d9ffb93f55c0e24624d4a52b3727d7f 704 Hamap MF_01920 ATP-dependent DNA helicase Rep [rep]. 3 687 35.804 T 12-10-2018 IPR005752 ATP-dependent DNA helicase Rep GO:0003677|GO:0004003|GO:0005524|GO:0006268 VAPA_1c07770 6d9ffb93f55c0e24624d4a52b3727d7f 704 Gene3D G3DSA:3.40.50.300 5 263 1.6E-83 T 12-10-2018 VAPA_1c07770 6d9ffb93f55c0e24624d4a52b3727d7f 704 Pfam PF00580 UvrD/REP helicase N-terminal domain 6 259 1.0E-64 T 12-10-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 VAPA_1c07770 6d9ffb93f55c0e24624d4a52b3727d7f 704 Gene3D G3DSA:1.10.10.160 105 180 1.6E-83 T 12-10-2018 IPR013986 DExx box DNA helicase domain superfamily VAPA_1c07770 6d9ffb93f55c0e24624d4a52b3727d7f 704 Gene3D G3DSA:3.40.50.300 271 663 1.4E-100 T 12-10-2018 VAPA_1c07770 6d9ffb93f55c0e24624d4a52b3727d7f 704 Pfam PF13361 UvrD-like helicase C-terminal domain 268 644 6.9E-56 T 12-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 VAPA_1c07770 6d9ffb93f55c0e24624d4a52b3727d7f 704 SUPERFAMILY SSF52540 3 664 3.51E-146 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c32340 4e839f44e4556c527b73ab2b01851b5b 301 Pfam PF00072 Response regulator receiver domain 14 125 6.3E-23 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_1c32340 4e839f44e4556c527b73ab2b01851b5b 301 SMART SM00421 239 296 1.2E-24 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_1c32340 4e839f44e4556c527b73ab2b01851b5b 301 SMART SM00448 12 125 5.6E-35 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_1c32340 4e839f44e4556c527b73ab2b01851b5b 301 Gene3D G3DSA:1.10.10.10 236 300 7.9E-24 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c32340 4e839f44e4556c527b73ab2b01851b5b 301 SUPERFAMILY SSF52172 6 136 1.25E-36 T 12-10-2018 IPR011006 CheY-like superfamily VAPA_1c32340 4e839f44e4556c527b73ab2b01851b5b 301 SUPERFAMILY SSF46894 235 296 3.2E-19 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 VAPA_1c32340 4e839f44e4556c527b73ab2b01851b5b 301 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 272 284 4.1E-12 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_1c32340 4e839f44e4556c527b73ab2b01851b5b 301 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 256 272 4.1E-12 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_1c32340 4e839f44e4556c527b73ab2b01851b5b 301 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 242 256 4.1E-12 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_1c32340 4e839f44e4556c527b73ab2b01851b5b 301 Gene3D G3DSA:3.40.50.12740 13 214 1.5E-40 T 12-10-2018 VAPA_1c32340 4e839f44e4556c527b73ab2b01851b5b 301 Pfam PF00196 Bacterial regulatory proteins, luxR family 241 296 3.9E-19 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_2c03440 d436bf38dd3158950b4e3eba4349d21e 240 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3 178 4.1E-5 T 12-10-2018 VAPA_2c03440 d436bf38dd3158950b4e3eba4349d21e 240 TIGRFAM TIGR01829 AcAcCoA_reduct: acetoacetyl-CoA reductase 3 239 3.5E-97 T 12-10-2018 IPR011283 Acetoacetyl-CoA reductase GO:0005737|GO:0018454|GO:0042619|GO:0055114 KEGG: 00630+1.1.1.36|KEGG: 00650+1.1.1.36|MetaCyc: PWY-5676|MetaCyc: PWY-5741|MetaCyc: PWY-7216|MetaCyc: PWY-7948 VAPA_2c03440 d436bf38dd3158950b4e3eba4349d21e 240 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 127 135 2.9E-15 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c03440 d436bf38dd3158950b4e3eba4349d21e 240 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 147 166 2.9E-15 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c03440 d436bf38dd3158950b4e3eba4349d21e 240 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 74 85 2.9E-15 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c03440 d436bf38dd3158950b4e3eba4349d21e 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 168 185 7.6E-46 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c03440 d436bf38dd3158950b4e3eba4349d21e 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 121 137 7.6E-46 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c03440 d436bf38dd3158950b4e3eba4349d21e 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 74 85 7.6E-46 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c03440 d436bf38dd3158950b4e3eba4349d21e 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 201 221 7.6E-46 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c03440 d436bf38dd3158950b4e3eba4349d21e 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 147 166 7.6E-46 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c03440 d436bf38dd3158950b4e3eba4349d21e 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 7.6E-46 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c03440 d436bf38dd3158950b4e3eba4349d21e 240 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 134 162 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 VAPA_2c03440 d436bf38dd3158950b4e3eba4349d21e 240 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 11 236 1.5E-56 T 12-10-2018 VAPA_2c03440 d436bf38dd3158950b4e3eba4349d21e 240 SUPERFAMILY SSF51735 3 239 2.27E-75 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_2c03440 d436bf38dd3158950b4e3eba4349d21e 240 Gene3D G3DSA:3.40.50.720 2 239 1.2E-75 T 12-10-2018 VAPA_1c41020 9ede21c137c21060f579c039a1986175 344 SUPERFAMILY SSF53850 30 264 1.63E-32 T 12-10-2018 VAPA_1c41020 9ede21c137c21060f579c039a1986175 344 Pfam PF09084 NMT1/THI5 like 50 257 5.7E-39 T 12-10-2018 IPR015168 SsuA/THI5-like VAPA_1c41020 9ede21c137c21060f579c039a1986175 344 Gene3D G3DSA:3.40.190.10 33 308 7.2E-57 T 12-10-2018 VAPA_1c41020 9ede21c137c21060f579c039a1986175 344 Gene3D G3DSA:3.40.190.10 116 219 7.2E-57 T 12-10-2018 VAPA_2c04110 baa2005710d0a12617b73e305ccba756 586 Pfam PF14791 DNA polymerase beta thumb 256 316 3.0E-21 T 12-10-2018 IPR029398 DNA polymerase beta, thumb domain VAPA_2c04110 baa2005710d0a12617b73e305ccba756 586 PRINTS PR00870 DNA-polymerase family X pol beta-like signature 256 263 5.9E-8 T 12-10-2018 IPR002008 DNA polymerase family X, beta-like GO:0003677|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 VAPA_2c04110 baa2005710d0a12617b73e305ccba756 586 PRINTS PR00870 DNA-polymerase family X pol beta-like signature 298 315 5.9E-8 T 12-10-2018 IPR002008 DNA polymerase family X, beta-like GO:0003677|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 VAPA_2c04110 baa2005710d0a12617b73e305ccba756 586 PRINTS PR00870 DNA-polymerase family X pol beta-like signature 241 249 5.9E-8 T 12-10-2018 IPR002008 DNA polymerase family X, beta-like GO:0003677|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 VAPA_2c04110 baa2005710d0a12617b73e305ccba756 586 PRINTS PR00870 DNA-polymerase family X pol beta-like signature 61 78 5.9E-8 T 12-10-2018 IPR002008 DNA polymerase family X, beta-like GO:0003677|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 VAPA_2c04110 baa2005710d0a12617b73e305ccba756 586 Gene3D G3DSA:3.20.20.140 329 585 8.7E-70 T 12-10-2018 VAPA_2c04110 baa2005710d0a12617b73e305ccba756 586 SMART SM00481 340 419 2.0E-12 T 12-10-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal VAPA_2c04110 baa2005710d0a12617b73e305ccba756 586 SUPERFAMILY SSF81301 159 316 4.31E-39 T 12-10-2018 VAPA_2c04110 baa2005710d0a12617b73e305ccba756 586 Gene3D G3DSA:3.30.460.10 158 262 4.4E-24 T 12-10-2018 VAPA_2c04110 baa2005710d0a12617b73e305ccba756 586 SUPERFAMILY SSF158702 79 150 4.97E-8 T 12-10-2018 VAPA_2c04110 baa2005710d0a12617b73e305ccba756 586 PIRSF PIRSF005047 3 574 3.1E-216 T 12-10-2018 IPR022311 Uncharacterised conserved protein UCP005047, YshC KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 VAPA_2c04110 baa2005710d0a12617b73e305ccba756 586 SMART SM00278 94 113 9.6 T 12-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 VAPA_2c04110 baa2005710d0a12617b73e305ccba756 586 SMART SM00278 54 73 3.2 T 12-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 VAPA_2c04110 baa2005710d0a12617b73e305ccba756 586 SMART SM00278 129 148 65.0 T 12-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 VAPA_2c04110 baa2005710d0a12617b73e305ccba756 586 Pfam PF14520 Helix-hairpin-helix domain 95 148 1.6E-8 T 12-10-2018 VAPA_2c04110 baa2005710d0a12617b73e305ccba756 586 Gene3D G3DSA:1.10.150.20 90 156 2.8E-18 T 12-10-2018 VAPA_2c04110 baa2005710d0a12617b73e305ccba756 586 SMART SM00483 3 316 1.4E-20 T 12-10-2018 IPR002054 DNA-directed DNA polymerase X GO:0003677|GO:0003887 VAPA_2c04110 baa2005710d0a12617b73e305ccba756 586 SUPERFAMILY SSF89550 339 569 1.7E-51 T 12-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 VAPA_2c04110 baa2005710d0a12617b73e305ccba756 586 Gene3D G3DSA:1.10.150.110 2 88 4.9E-22 T 12-10-2018 IPR027421 DNA polymerase lambda lyase domain superfamily VAPA_2c04110 baa2005710d0a12617b73e305ccba756 586 Gene3D G3DSA:3.30.210.10 263 327 1.1E-26 T 12-10-2018 IPR037160 DNA polymerase, thumb domain superfamily VAPA_2c04110 baa2005710d0a12617b73e305ccba756 586 Pfam PF14716 Helix-hairpin-helix domain 5 74 4.4E-20 T 12-10-2018 IPR010996 DNA polymerase beta-like, N-terminal domain VAPA_2c04110 baa2005710d0a12617b73e305ccba756 586 SUPERFAMILY SSF47802 2 82 9.16E-18 T 12-10-2018 IPR027421 DNA polymerase lambda lyase domain superfamily VAPA_2c04110 baa2005710d0a12617b73e305ccba756 586 Pfam PF02811 PHP domain 341 438 3.8E-6 T 12-10-2018 IPR004013 PHP domain GO:0003824 VAPA_1c38520 17a32f68ba10da4c83ee0146e1ee1122 164 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 84 162 1.6E-32 T 12-10-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 VAPA_1c38520 17a32f68ba10da4c83ee0146e1ee1122 164 Hamap MF_00772 Methylated-DNA--protein-cysteine methyltransferase [ogt]. 12 163 41.519 T 12-10-2018 IPR023546 Methylated-DNA--protein-cysteine methyltransferase GO:0003824|GO:0006281 VAPA_1c38520 17a32f68ba10da4c83ee0146e1ee1122 164 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 133 139 - T 12-10-2018 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 Reactome: R-HSA-5657655 VAPA_1c38520 17a32f68ba10da4c83ee0146e1ee1122 164 Pfam PF02870 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain 8 73 1.7E-6 T 12-10-2018 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 VAPA_1c38520 17a32f68ba10da4c83ee0146e1ee1122 164 Gene3D G3DSA:3.30.160.70 7 78 4.2E-21 T 12-10-2018 VAPA_1c38520 17a32f68ba10da4c83ee0146e1ee1122 164 SUPERFAMILY SSF46767 82 162 4.84E-31 T 12-10-2018 IPR036217 Methylated DNA-protein cysteine methyltransferase, DNA binding domain Reactome: R-HSA-5657655 VAPA_1c38520 17a32f68ba10da4c83ee0146e1ee1122 164 SUPERFAMILY SSF53155 9 87 9.61E-18 T 12-10-2018 IPR036631 Methylated DNA-protein cysteine methyltransferase domain superfamily GO:0003908|GO:0006281 Reactome: R-HSA-5657655 VAPA_1c38520 17a32f68ba10da4c83ee0146e1ee1122 164 Gene3D G3DSA:1.10.10.10 80 164 4.6E-36 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c38520 17a32f68ba10da4c83ee0146e1ee1122 164 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 83 162 2.0E-34 T 12-10-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 VAPA_2c01730 82ad08c72abc8798d528fb8f1b381b86 364 Gene3D G3DSA:1.10.260.40 1 56 1.1E-17 T 12-10-2018 VAPA_2c01730 82ad08c72abc8798d528fb8f1b381b86 364 Pfam PF13377 Periplasmic binding protein-like domain 173 342 1.1E-32 T 12-10-2018 VAPA_2c01730 82ad08c72abc8798d528fb8f1b381b86 364 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 49 8.3E-13 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 VAPA_2c01730 82ad08c72abc8798d528fb8f1b381b86 364 Gene3D G3DSA:3.40.50.2300 165 301 3.5E-62 T 12-10-2018 VAPA_2c01730 82ad08c72abc8798d528fb8f1b381b86 364 SUPERFAMILY SSF53822 63 347 1.99E-54 T 12-10-2018 IPR028082 Periplasmic binding protein-like I VAPA_2c01730 82ad08c72abc8798d528fb8f1b381b86 364 ProSitePatterns PS00356 LacI-type HTH domain signature. 4 22 - T 12-10-2018 VAPA_2c01730 82ad08c72abc8798d528fb8f1b381b86 364 Gene3D G3DSA:3.40.50.2300 57 317 3.5E-62 T 12-10-2018 VAPA_2c01730 82ad08c72abc8798d528fb8f1b381b86 364 SUPERFAMILY SSF47413 1 60 5.63E-13 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 VAPA_2c01730 82ad08c72abc8798d528fb8f1b381b86 364 SMART SM00354 1 72 3.4E-25 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 VAPA_1c13420 f08ffbf56084b1c5be6b117ddaaf62b2 198 Pfam PF00551 Formyl transferase 2 186 3.3E-56 T 12-10-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 VAPA_1c13420 f08ffbf56084b1c5be6b117ddaaf62b2 198 TIGRFAM TIGR00639 PurN: phosphoribosylglycinamide formyltransferase 2 192 5.0E-68 T 12-10-2018 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 VAPA_1c13420 f08ffbf56084b1c5be6b117ddaaf62b2 198 Hamap MF_01930 Phosphoribosylglycinamide formyltransferase [purN]. 3 192 31.113 T 12-10-2018 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 VAPA_1c13420 f08ffbf56084b1c5be6b117ddaaf62b2 198 Gene3D G3DSA:3.40.50.170 1 198 1.7E-75 T 12-10-2018 VAPA_1c13420 f08ffbf56084b1c5be6b117ddaaf62b2 198 SUPERFAMILY SSF53328 2 193 3.4E-61 T 12-10-2018 IPR036477 Formyl transferase, N-terminal domain superfamily GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 VAPA_1c31610 d88f00ee80c6b23b6472ca3a00a7524f 170 SUPERFAMILY SSF50891 2 166 1.61E-54 T 12-10-2018 IPR029000 Cyclophilin-like domain superfamily VAPA_1c31610 d88f00ee80c6b23b6472ca3a00a7524f 170 PIRSF PIRSF001467 1 170 1.7E-26 T 12-10-2018 IPR024936 Cyclophilin-type peptidyl-prolyl cis-trans isomerase GO:0003755 VAPA_1c31610 d88f00ee80c6b23b6472ca3a00a7524f 170 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 46 58 1.6E-11 T 12-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 VAPA_1c31610 d88f00ee80c6b23b6472ca3a00a7524f 170 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 20 35 1.6E-11 T 12-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 VAPA_1c31610 d88f00ee80c6b23b6472ca3a00a7524f 170 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 123 138 1.6E-11 T 12-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 VAPA_1c31610 d88f00ee80c6b23b6472ca3a00a7524f 170 ProSitePatterns PS00170 Cyclophilin-type peptidyl-prolyl cis-trans isomerase signature. 41 58 - T 12-10-2018 IPR020892 Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site GO:0003755|GO:0006457 VAPA_1c31610 d88f00ee80c6b23b6472ca3a00a7524f 170 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 6 165 1.3E-44 T 12-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 VAPA_1c31610 d88f00ee80c6b23b6472ca3a00a7524f 170 Gene3D G3DSA:2.40.100.10 2 168 2.6E-65 T 12-10-2018 IPR029000 Cyclophilin-like domain superfamily VAPA_1c03450 c58079ba0e557e5e8703ffa2de6b9908 99 Pfam PF02686 Glu-tRNAGln amidotransferase C subunit 21 94 2.4E-15 T 12-10-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 VAPA_1c03450 c58079ba0e557e5e8703ffa2de6b9908 99 TIGRFAM TIGR00135 gatC: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, C subunit 4 99 1.1E-23 T 12-10-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 VAPA_1c03450 c58079ba0e557e5e8703ffa2de6b9908 99 SUPERFAMILY SSF141000 3 97 1.44E-23 T 12-10-2018 IPR036113 Glu-tRNAGln amidotransferase superfamily, subunit C GO:0006450 VAPA_1c03450 c58079ba0e557e5e8703ffa2de6b9908 99 Gene3D G3DSA:1.10.20.60 1 97 7.6E-19 T 12-10-2018 VAPA_1c03450 c58079ba0e557e5e8703ffa2de6b9908 99 Hamap MF_00122 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C [gatC]. 2 99 19.805 T 12-10-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 VAPA_1c07650 247acdb57cd196b4227d7c40ec29b420 327 PIRSF PIRSF017082 1 327 4.7E-77 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c07650 247acdb57cd196b4227d7c40ec29b420 327 Gene3D G3DSA:3.40.190.150 31 316 8.2E-110 T 12-10-2018 VAPA_1c07650 247acdb57cd196b4227d7c40ec29b420 327 Gene3D G3DSA:3.40.190.10 129 252 8.2E-110 T 12-10-2018 VAPA_1c07650 247acdb57cd196b4227d7c40ec29b420 327 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 51 317 1.1E-79 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c07650 247acdb57cd196b4227d7c40ec29b420 327 SUPERFAMILY SSF53850 114 286 1.21E-14 T 12-10-2018 VAPA_1c51290 3060123ab98721e4fc4b8c95dd73020b 260 SUPERFAMILY SSF53067 128 253 2.42E-28 T 12-10-2018 VAPA_1c51290 3060123ab98721e4fc4b8c95dd73020b 260 Gene3D G3DSA:3.30.420.490 129 244 1.2E-67 T 12-10-2018 VAPA_1c51290 3060123ab98721e4fc4b8c95dd73020b 260 Pfam PF03309 Type III pantothenate kinase 5 208 1.2E-56 T 12-10-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 VAPA_1c51290 3060123ab98721e4fc4b8c95dd73020b 260 SUPERFAMILY SSF53067 5 119 4.66E-28 T 12-10-2018 VAPA_1c51290 3060123ab98721e4fc4b8c95dd73020b 260 Gene3D G3DSA:3.30.420.40 6 249 1.2E-67 T 12-10-2018 VAPA_1c51290 3060123ab98721e4fc4b8c95dd73020b 260 Hamap MF_01274 Type III pantothenate kinase [coaX]. 4 256 17.287 T 12-10-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 VAPA_1c51290 3060123ab98721e4fc4b8c95dd73020b 260 TIGRFAM TIGR00671 baf: pantothenate kinase, type III 5 247 2.4E-27 T 12-10-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 VAPA_1c48850 193312a4ccf8d9ae5278b6bc70b74389 359 Gene3D G3DSA:3.60.15.10 23 291 1.5E-56 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like VAPA_1c48850 193312a4ccf8d9ae5278b6bc70b74389 359 Gene3D G3DSA:1.10.10.10 297 349 4.0E-6 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c48850 193312a4ccf8d9ae5278b6bc70b74389 359 SUPERFAMILY SSF56281 15 349 4.87E-68 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like VAPA_1c48850 193312a4ccf8d9ae5278b6bc70b74389 359 SMART SM00849 42 264 2.3E-20 T 12-10-2018 IPR001279 Metallo-beta-lactamase VAPA_1c48850 193312a4ccf8d9ae5278b6bc70b74389 359 Pfam PF00753 Metallo-beta-lactamase superfamily 41 264 1.3E-20 T 12-10-2018 IPR001279 Metallo-beta-lactamase VAPA_1c30330 756b75f4c59cee191b6f9f9c0103453b 391 SUPERFAMILY SSF161098 156 339 6.41E-43 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c30330 756b75f4c59cee191b6f9f9c0103453b 391 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 178 344 1.6E-27 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 VAPA_1c30330 756b75f4c59cee191b6f9f9c0103453b 391 Gene3D G3DSA:1.10.3720.10 152 344 8.2E-38 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c37830 020d60fe863f494f1b698f9c7ccfe8cc 146 TIGRFAM TIGR03562 osmo_induc_OsmC: peroxiredoxin, OsmC subfamily 5 142 1.1E-55 T 12-10-2018 IPR019904 Peroxiredoxin OsmC GO:0004601|GO:0006979 KEGG: 00480+1.11.1.15 VAPA_1c37830 020d60fe863f494f1b698f9c7ccfe8cc 146 SUPERFAMILY SSF82784 6 141 1.07E-33 T 12-10-2018 IPR036102 OsmC/Ohr superfamily VAPA_1c37830 020d60fe863f494f1b698f9c7ccfe8cc 146 Gene3D G3DSA:3.30.300.20 2 143 2.5E-40 T 12-10-2018 IPR015946 K homology domain-like, alpha/beta VAPA_1c37830 020d60fe863f494f1b698f9c7ccfe8cc 146 Pfam PF02566 OsmC-like protein 44 140 2.9E-18 T 12-10-2018 IPR003718 OsmC/Ohr family VAPA_1c15540 7d926de23c61f00ca3a3c0dba545c002 321 SUPERFAMILY SSF46689 218 267 1.25E-6 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 VAPA_1c15540 7d926de23c61f00ca3a3c0dba545c002 321 Gene3D G3DSA:1.10.10.60 217 315 3.9E-15 T 12-10-2018 VAPA_1c15540 7d926de23c61f00ca3a3c0dba545c002 321 SUPERFAMILY SSF52317 2 198 2.52E-26 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like VAPA_1c15540 7d926de23c61f00ca3a3c0dba545c002 321 Pfam PF01965 DJ-1/PfpI family 71 174 1.3E-8 T 12-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 VAPA_1c15540 7d926de23c61f00ca3a3c0dba545c002 321 SMART SM00342 233 316 3.5E-8 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 VAPA_1c15540 7d926de23c61f00ca3a3c0dba545c002 321 Gene3D G3DSA:3.40.50.880 1 203 2.0E-40 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like VAPA_1c15540 7d926de23c61f00ca3a3c0dba545c002 321 Pfam PF12833 Helix-turn-helix domain 239 305 5.4E-13 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 VAPA_1c38360 54ab3f2e358972f9948521e00c449707 180 Gene3D G3DSA:2.60.40.200 41 180 6.2E-45 T 12-10-2018 IPR036423 Superoxide dismutase-like, copper/zinc binding domain superfamily GO:0006801|GO:0046872 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 VAPA_1c38360 54ab3f2e358972f9948521e00c449707 180 PRINTS PR00068 Cu-Zn-superoxide dismutase family signature 76 98 3.2E-9 T 12-10-2018 IPR001424 Superoxide dismutase, copper/zinc binding domain GO:0006801|GO:0046872 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 VAPA_1c38360 54ab3f2e358972f9948521e00c449707 180 PRINTS PR00068 Cu-Zn-superoxide dismutase family signature 112 121 3.2E-9 T 12-10-2018 IPR001424 Superoxide dismutase, copper/zinc binding domain GO:0006801|GO:0046872 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 VAPA_1c38360 54ab3f2e358972f9948521e00c449707 180 PRINTS PR00068 Cu-Zn-superoxide dismutase family signature 152 178 3.2E-9 T 12-10-2018 IPR001424 Superoxide dismutase, copper/zinc binding domain GO:0006801|GO:0046872 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 VAPA_1c38360 54ab3f2e358972f9948521e00c449707 180 Pfam PF00080 Copper/zinc superoxide dismutase (SODC) 46 177 3.3E-40 T 12-10-2018 IPR001424 Superoxide dismutase, copper/zinc binding domain GO:0006801|GO:0046872 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 VAPA_1c38360 54ab3f2e358972f9948521e00c449707 180 SUPERFAMILY SSF49329 40 177 3.93E-42 T 12-10-2018 IPR036423 Superoxide dismutase-like, copper/zinc binding domain superfamily GO:0006801|GO:0046872 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 VAPA_1c38360 54ab3f2e358972f9948521e00c449707 180 ProSitePatterns PS00087 Copper/Zinc superoxide dismutase signature 1. 76 86 - T 12-10-2018 IPR018152 Superoxide dismutase, copper/zinc, binding site GO:0004784|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 VAPA_1c38360 54ab3f2e358972f9948521e00c449707 180 ProSitePatterns PS00332 Copper/Zinc superoxide dismutase signature 2. 166 177 - T 12-10-2018 IPR018152 Superoxide dismutase, copper/zinc, binding site GO:0004784|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 VAPA_1c24290 653b43c25080f5c6481338999a325e36 312 SUPERFAMILY SSF51182 61 306 5.51E-36 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily VAPA_1c24290 653b43c25080f5c6481338999a325e36 312 Gene3D G3DSA:2.60.120.10 71 159 1.7E-12 T 12-10-2018 IPR014710 RmlC-like jelly roll fold VAPA_1c24290 653b43c25080f5c6481338999a325e36 312 Pfam PF07883 Cupin domain 84 148 1.4E-7 T 12-10-2018 IPR013096 Cupin 2, conserved barrel VAPA_1c24290 653b43c25080f5c6481338999a325e36 312 Pfam PF07883 Cupin domain 226 291 8.6E-7 T 12-10-2018 IPR013096 Cupin 2, conserved barrel VAPA_1c24290 653b43c25080f5c6481338999a325e36 312 Gene3D G3DSA:2.60.120.10 160 311 1.8E-31 T 12-10-2018 IPR014710 RmlC-like jelly roll fold VAPA_1c38640 f71fb7138f2262f982d8f4463bf392c7 344 Pfam PF13523 Acetyltransferase (GNAT) domain 163 308 9.9E-52 T 12-10-2018 VAPA_1c38640 f71fb7138f2262f982d8f4463bf392c7 344 SMART SM01006 160 207 4.4E-15 T 12-10-2018 IPR019432 Siderophore biosynthesis protein, conserved domain VAPA_1c38640 f71fb7138f2262f982d8f4463bf392c7 344 Gene3D G3DSA:3.40.630.30 119 323 8.0E-64 T 12-10-2018 VAPA_1c38640 f71fb7138f2262f982d8f4463bf392c7 344 SUPERFAMILY SSF55729 128 322 2.79E-60 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase VAPA_1c31310 4ec1008fa13ced56647c8a5fe6121e7b 561 Pfam PF07969 Amidohydrolase family 43 490 1.1E-57 T 12-10-2018 IPR013108 Amidohydrolase 3 VAPA_1c31310 4ec1008fa13ced56647c8a5fe6121e7b 561 TIGRFAM TIGR03121 one_C_dehyd_A: formylmethanofuran dehydrogenase subunit A 5 539 3.7E-210 T 12-10-2018 IPR012027 Formylmethanofuran dehydrogenase, subunit A VAPA_1c31310 4ec1008fa13ced56647c8a5fe6121e7b 561 SUPERFAMILY SSF51338 427 512 9.87E-21 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 VAPA_1c31310 4ec1008fa13ced56647c8a5fe6121e7b 561 SUPERFAMILY SSF51556 55 454 7.37E-30 T 12-10-2018 IPR032466 Metal-dependent hydrolase VAPA_1c31310 4ec1008fa13ced56647c8a5fe6121e7b 561 SUPERFAMILY SSF51338 4 64 9.26E-14 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 VAPA_1c31310 4ec1008fa13ced56647c8a5fe6121e7b 561 PIRSF PIRSF006453 2 554 3.7E-226 T 12-10-2018 IPR012027 Formylmethanofuran dehydrogenase, subunit A VAPA_1c31310 4ec1008fa13ced56647c8a5fe6121e7b 561 Gene3D G3DSA:3.20.20.140 1 71 4.2E-10 T 12-10-2018 VAPA_1c26110 4af33ccca5509ae290aa57211a0f9e6f 868 PIRSF PIRSF006288 4 868 5.2E-290 T 12-10-2018 IPR010043 Bifunctional uridylyltransferase/uridylyl-removing enzyme GO:0006807|GO:0008773 VAPA_1c26110 4af33ccca5509ae290aa57211a0f9e6f 868 SUPERFAMILY SSF55021 687 742 3.82E-9 T 12-10-2018 VAPA_1c26110 4af33ccca5509ae290aa57211a0f9e6f 868 Pfam PF01966 HD domain 446 574 3.8E-8 T 12-10-2018 IPR006674 HD domain VAPA_1c26110 4af33ccca5509ae290aa57211a0f9e6f 868 TIGRFAM TIGR01693 UTase_glnD: protein-P-II uridylyltransferase 35 866 2.9E-231 T 12-10-2018 IPR010043 Bifunctional uridylyltransferase/uridylyl-removing enzyme GO:0006807|GO:0008773 VAPA_1c26110 4af33ccca5509ae290aa57211a0f9e6f 868 SMART SM00471 441 588 5.7E-6 T 12-10-2018 IPR003607 HD/PDEase domain VAPA_1c26110 4af33ccca5509ae290aa57211a0f9e6f 868 SUPERFAMILY SSF109604 411 536 2.86E-13 T 12-10-2018 VAPA_1c26110 4af33ccca5509ae290aa57211a0f9e6f 868 Hamap MF_00277 Bifunctional uridylyltransferase/uridylyl-removing enzyme [glnD]. 1 868 306.961 T 12-10-2018 IPR010043 Bifunctional uridylyltransferase/uridylyl-removing enzyme GO:0006807|GO:0008773 VAPA_1c26110 4af33ccca5509ae290aa57211a0f9e6f 868 Pfam PF01909 Nucleotidyltransferase domain 64 107 7.3E-5 T 12-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 VAPA_1c26110 4af33ccca5509ae290aa57211a0f9e6f 868 Pfam PF08335 GlnD PII-uridylyltransferase 171 309 5.5E-30 T 12-10-2018 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 VAPA_1c26110 4af33ccca5509ae290aa57211a0f9e6f 868 Gene3D G3DSA:3.30.70.260 795 868 2.8E-7 T 12-10-2018 VAPA_1c26110 4af33ccca5509ae290aa57211a0f9e6f 868 SUPERFAMILY SSF55021 797 848 1.6E-8 T 12-10-2018 VAPA_1c26110 4af33ccca5509ae290aa57211a0f9e6f 868 SUPERFAMILY SSF81593 177 305 6.04E-7 T 12-10-2018 VAPA_1c26110 4af33ccca5509ae290aa57211a0f9e6f 868 SUPERFAMILY SSF81301 17 164 6.54E-22 T 12-10-2018 VAPA_1c26110 4af33ccca5509ae290aa57211a0f9e6f 868 Gene3D G3DSA:1.10.3210.10 423 554 1.2E-8 T 12-10-2018 VAPA_2c10670 eff4dd4dd6972513ea00b66e3ec559e9 329 SUPERFAMILY SSF53850 118 296 7.97E-14 T 12-10-2018 VAPA_2c10670 eff4dd4dd6972513ea00b66e3ec559e9 329 PIRSF PIRSF017082 1 328 2.8E-75 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_2c10670 eff4dd4dd6972513ea00b66e3ec559e9 329 Gene3D G3DSA:3.40.190.10 132 254 3.2E-97 T 12-10-2018 VAPA_2c10670 eff4dd4dd6972513ea00b66e3ec559e9 329 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 54 325 1.5E-73 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_2c10670 eff4dd4dd6972513ea00b66e3ec559e9 329 Gene3D G3DSA:3.40.190.150 34 319 3.2E-97 T 12-10-2018 VAPA_1c50340 8e73531d1c1b275d59c60c17aa22486b 551 SUPERFAMILY SSF50249 423 549 1.88E-29 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold VAPA_1c50340 8e73531d1c1b275d59c60c17aa22486b 551 SUPERFAMILY SSF56091 212 418 2.02E-52 T 12-10-2018 VAPA_1c50340 8e73531d1c1b275d59c60c17aa22486b 551 TIGRFAM TIGR04120 DNA_lig_bact: DNA ligase, ATP-dependent, PP_1105 family 2 549 3.0E-215 T 12-10-2018 IPR026333 ATP-dependent DNA ligase, PP_1105 family VAPA_1c50340 8e73531d1c1b275d59c60c17aa22486b 551 Pfam PF01068 ATP dependent DNA ligase domain 236 418 3.9E-24 T 12-10-2018 IPR012310 DNA ligase, ATP-dependent, central GO:0003910|GO:0005524|GO:0006281|GO:0006310 VAPA_1c50340 8e73531d1c1b275d59c60c17aa22486b 551 Pfam PF04679 ATP dependent DNA ligase C terminal region 439 534 2.6E-10 T 12-10-2018 IPR012309 DNA ligase, ATP-dependent, C-terminal GO:0003910|GO:0006281|GO:0006310 VAPA_1c50340 8e73531d1c1b275d59c60c17aa22486b 551 ProSitePatterns PS00697 ATP-dependent DNA ligase AMP-binding site. 242 250 - T 12-10-2018 IPR016059 DNA ligase, ATP-dependent, conserved site GO:0003909|GO:0051103 VAPA_1c50340 8e73531d1c1b275d59c60c17aa22486b 551 Gene3D G3DSA:3.30.470.30 216 418 2.7E-41 T 12-10-2018 VAPA_1c50340 8e73531d1c1b275d59c60c17aa22486b 551 Pfam PF04675 DNA ligase N terminus 3 164 2.6E-19 T 12-10-2018 IPR012308 DNA ligase, ATP-dependent, N-terminal GO:0003677|GO:0003910|GO:0006281|GO:0006310 VAPA_1c50340 8e73531d1c1b275d59c60c17aa22486b 551 Gene3D G3DSA:2.40.50.140 422 551 4.4E-31 T 12-10-2018 VAPA_1c22980 6109d9e05ceee8bafe5e5213d8f2c8a7 514 Pfam PF01039 Carboxyl transferase domain 27 512 1.7E-194 T 12-10-2018 IPR034733 Acetyl-CoA carboxylase MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722|Reactome: R-HSA-196780 VAPA_1c22980 6109d9e05ceee8bafe5e5213d8f2c8a7 514 Gene3D G3DSA:3.90.226.10 1 256 1.4E-98 T 12-10-2018 VAPA_1c22980 6109d9e05ceee8bafe5e5213d8f2c8a7 514 Gene3D G3DSA:3.90.226.10 262 514 1.5E-94 T 12-10-2018 VAPA_1c22980 6109d9e05ceee8bafe5e5213d8f2c8a7 514 SUPERFAMILY SSF52096 242 514 1.78E-87 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily VAPA_1c22980 6109d9e05ceee8bafe5e5213d8f2c8a7 514 SUPERFAMILY SSF52096 3 249 1.37E-80 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily VAPA_1c28930 cdf90d489c00d21de853c7de62ea8c8c 436 SUPERFAMILY SSF55874 289 434 2.36E-30 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_1c28930 cdf90d489c00d21de853c7de62ea8c8c 436 Gene3D G3DSA:3.30.565.10 289 435 3.2E-30 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_1c28930 cdf90d489c00d21de853c7de62ea8c8c 436 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 330 433 4.0E-13 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase VAPA_1c28930 cdf90d489c00d21de853c7de62ea8c8c 436 SUPERFAMILY SSF47384 209 285 5.1E-14 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 VAPA_1c28930 cdf90d489c00d21de853c7de62ea8c8c 436 SMART SM00304 173 225 8.7E-13 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 VAPA_1c28930 cdf90d489c00d21de853c7de62ea8c8c 436 PRINTS PR00344 Bacterial sensor protein C-terminal signature 419 432 3.4E-9 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c28930 cdf90d489c00d21de853c7de62ea8c8c 436 PRINTS PR00344 Bacterial sensor protein C-terminal signature 361 375 3.4E-9 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c28930 cdf90d489c00d21de853c7de62ea8c8c 436 PRINTS PR00344 Bacterial sensor protein C-terminal signature 395 413 3.4E-9 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c28930 cdf90d489c00d21de853c7de62ea8c8c 436 Gene3D G3DSA:1.10.287.130 172 283 8.1E-23 T 12-10-2018 VAPA_1c28930 cdf90d489c00d21de853c7de62ea8c8c 436 SMART SM00388 226 287 2.3E-13 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 VAPA_1c28930 cdf90d489c00d21de853c7de62ea8c8c 436 SMART SM00387 326 435 1.3E-19 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase VAPA_1c28930 cdf90d489c00d21de853c7de62ea8c8c 436 SUPERFAMILY SSF158472 174 222 2.75E-6 T 12-10-2018 VAPA_1c28930 cdf90d489c00d21de853c7de62ea8c8c 436 Pfam PF00672 HAMP domain 173 222 8.0E-10 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 VAPA_1c28930 cdf90d489c00d21de853c7de62ea8c8c 436 Pfam PF00512 His Kinase A (phospho-acceptor) domain 229 286 4.8E-12 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 VAPA_2c11080 3f6c838fa0510ee26a073b6eff555ef2 492 Gene3D G3DSA:3.30.70.2740 354 440 2.6E-28 T 12-10-2018 VAPA_2c11080 3f6c838fa0510ee26a073b6eff555ef2 492 SUPERFAMILY SSF55103 203 482 9.32E-54 T 12-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 VAPA_2c11080 3f6c838fa0510ee26a073b6eff555ef2 492 SUPERFAMILY SSF56176 14 229 1.17E-70 T 12-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 VAPA_2c11080 3f6c838fa0510ee26a073b6eff555ef2 492 Gene3D G3DSA:3.30.43.10 6 105 1.7E-26 T 12-10-2018 IPR016167 FAD-binding, type PCMH, subdomain 1 VAPA_2c11080 3f6c838fa0510ee26a073b6eff555ef2 492 Pfam PF02913 FAD linked oxidases, C-terminal domain 229 479 6.9E-44 T 12-10-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 VAPA_2c11080 3f6c838fa0510ee26a073b6eff555ef2 492 Gene3D G3DSA:1.10.45.10 441 481 1.6E-10 T 12-10-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 VAPA_2c11080 3f6c838fa0510ee26a073b6eff555ef2 492 Pfam PF01565 FAD binding domain 52 191 2.4E-35 T 12-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 VAPA_2c11080 3f6c838fa0510ee26a073b6eff555ef2 492 Gene3D G3DSA:3.30.465.10 108 228 2.4E-42 T 12-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 VAPA_2c11080 3f6c838fa0510ee26a073b6eff555ef2 492 Gene3D G3DSA:3.30.70.2190 229 353 2.2E-33 T 12-10-2018 VAPA_1c52740 fd3e4dae847a4a5a0d8ad637b67c7215 260 Pfam PF03167 Uracil DNA glycosylase superfamily 112 249 1.3E-14 T 12-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 VAPA_1c52740 fd3e4dae847a4a5a0d8ad637b67c7215 260 SUPERFAMILY SSF52141 107 255 4.91E-25 T 12-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 VAPA_1c52740 fd3e4dae847a4a5a0d8ad637b67c7215 260 Gene3D G3DSA:3.40.470.10 100 258 1.7E-25 T 12-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 VAPA_1c52740 fd3e4dae847a4a5a0d8ad637b67c7215 260 SMART SM00986 103 250 1.4E-6 T 12-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 VAPA_1c52740 fd3e4dae847a4a5a0d8ad637b67c7215 260 SMART SM00987 103 250 1.4E-6 T 12-10-2018 VAPA_1c00510 c792d07a9c3e33832927cc5ba797345f 474 Gene3D G3DSA:3.30.465.40 34 247 1.2E-72 T 12-10-2018 VAPA_1c00510 c792d07a9c3e33832927cc5ba797345f 474 Pfam PF02913 FAD linked oxidases, C-terminal domain 231 471 2.9E-64 T 12-10-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 VAPA_1c00510 c792d07a9c3e33832927cc5ba797345f 474 Gene3D G3DSA:1.10.45.10 432 472 7.2E-15 T 12-10-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 VAPA_1c00510 c792d07a9c3e33832927cc5ba797345f 474 Pfam PF01565 FAD binding domain 57 194 7.3E-40 T 12-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 VAPA_1c00510 c792d07a9c3e33832927cc5ba797345f 474 Gene3D G3DSA:3.30.70.2740 349 431 5.4E-10 T 12-10-2018 VAPA_1c00510 c792d07a9c3e33832927cc5ba797345f 474 SUPERFAMILY SSF56176 13 231 1.21E-69 T 12-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 VAPA_1c00510 c792d07a9c3e33832927cc5ba797345f 474 SUPERFAMILY SSF55103 234 472 3.6E-67 T 12-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 VAPA_1c29630 e9f649cc16fcf82fba9c93708936a670 468 Hamap MF_01865 Ribosomal protein S12 methylthiotransferase RimO [rimO]. 16 467 58.461 T 12-10-2018 IPR005840 Ribosomal protein S12 methylthiotransferase RimO GO:0005737|GO:0016740|GO:0018339|GO:0051539 VAPA_1c29630 e9f649cc16fcf82fba9c93708936a670 468 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 17 464 6.3E-93 T 12-10-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 VAPA_1c29630 e9f649cc16fcf82fba9c93708936a670 468 TIGRFAM TIGR01125 TIGR01125: ribosomal protein S12 methylthiotransferase RimO 17 464 5.6E-155 T 12-10-2018 IPR005840 Ribosomal protein S12 methylthiotransferase RimO GO:0005737|GO:0016740|GO:0018339|GO:0051539 VAPA_1c29630 e9f649cc16fcf82fba9c93708936a670 468 SUPERFAMILY SSF102114 152 390 1.06E-46 T 12-10-2018 VAPA_1c29630 e9f649cc16fcf82fba9c93708936a670 468 SMART SM00729 156 385 4.9E-49 T 12-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 VAPA_1c29630 e9f649cc16fcf82fba9c93708936a670 468 Gene3D G3DSA:3.80.30.20 154 399 5.4E-65 T 12-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe VAPA_1c29630 e9f649cc16fcf82fba9c93708936a670 468 Gene3D G3DSA:3.40.50.12160 17 139 1.6E-25 T 12-10-2018 IPR038135 Methylthiotransferase, N-terminal domain superfamily VAPA_1c29630 e9f649cc16fcf82fba9c93708936a670 468 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 160 180 - T 12-10-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 VAPA_1c29630 e9f649cc16fcf82fba9c93708936a670 468 Pfam PF04055 Radical SAM superfamily 162 343 5.1E-28 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 VAPA_1c29630 e9f649cc16fcf82fba9c93708936a670 468 Gene3D G3DSA:2.40.50.140 400 468 2.9E-12 T 12-10-2018 VAPA_1c29630 e9f649cc16fcf82fba9c93708936a670 468 Pfam PF00919 Uncharacterized protein family UPF0004 17 97 7.6E-19 T 12-10-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 VAPA_2c12030 fb86d6a281ea7584025eb6a7b4bdf292 289 Gene3D G3DSA:3.40.50.1820 34 285 3.0E-57 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_2c12030 fb86d6a281ea7584025eb6a7b4bdf292 289 Pfam PF07859 alpha/beta hydrolase fold 78 191 4.5E-14 T 12-10-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0016787 VAPA_2c12030 fb86d6a281ea7584025eb6a7b4bdf292 289 SUPERFAMILY SSF53474 19 286 5.54E-46 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_2c12030 fb86d6a281ea7584025eb6a7b4bdf292 289 ProSitePatterns PS00122 Carboxylesterases type-B serine active site. 141 156 - T 12-10-2018 IPR019826 Carboxylesterase type B, active site VAPA_1c33530 3d085b3c7abf3fcf61e590b078377eae 388 ProSitePatterns PS00480 Citrate synthase signature. 270 282 - T 12-10-2018 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 Reactome: R-HSA-1268020|Reactome: R-HSA-71403 VAPA_1c33530 3d085b3c7abf3fcf61e590b078377eae 388 Gene3D G3DSA:1.10.230.10 236 334 3.4E-124 T 12-10-2018 IPR016143 Citrate synthase-like, small alpha subdomain VAPA_1c33530 3d085b3c7abf3fcf61e590b078377eae 388 TIGRFAM TIGR01800 cit_synth_II: 2-methylcitrate synthase/citrate synthase II 20 387 5.3E-154 T 12-10-2018 IPR011278 2-methylcitrate synthase/citrate synthase type I GO:0005737|GO:0046912 VAPA_1c33530 3d085b3c7abf3fcf61e590b078377eae 388 Gene3D G3DSA:1.10.580.10 41 367 3.4E-124 T 12-10-2018 IPR016142 Citrate synthase-like, large alpha subdomain Reactome: R-HSA-1268020|Reactome: R-HSA-71403 VAPA_1c33530 3d085b3c7abf3fcf61e590b078377eae 388 Pfam PF00285 Citrate synthase, C-terminal domain 21 369 1.3E-110 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 VAPA_1c33530 3d085b3c7abf3fcf61e590b078377eae 388 PIRSF PIRSF001369 14 388 2.7E-108 T 12-10-2018 IPR024176 Citrate synthase, bacterial-type VAPA_1c33530 3d085b3c7abf3fcf61e590b078377eae 388 PRINTS PR00143 Citrate synthase signature 320 336 6.6E-36 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 VAPA_1c33530 3d085b3c7abf3fcf61e590b078377eae 388 PRINTS PR00143 Citrate synthase signature 340 354 6.6E-36 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 VAPA_1c33530 3d085b3c7abf3fcf61e590b078377eae 388 PRINTS PR00143 Citrate synthase signature 263 283 6.6E-36 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 VAPA_1c33530 3d085b3c7abf3fcf61e590b078377eae 388 PRINTS PR00143 Citrate synthase signature 138 151 6.6E-36 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 VAPA_1c33530 3d085b3c7abf3fcf61e590b078377eae 388 PRINTS PR00143 Citrate synthase signature 188 203 6.6E-36 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 VAPA_1c33530 3d085b3c7abf3fcf61e590b078377eae 388 PRINTS PR00143 Citrate synthase signature 210 238 6.6E-36 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 VAPA_1c33530 3d085b3c7abf3fcf61e590b078377eae 388 SUPERFAMILY SSF48256 21 379 3.14E-120 T 12-10-2018 IPR036969 Citrate synthase superfamily GO:0046912 VAPA_2c00640 64e07940387e2f55b448f050cc424b83 237 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 44 58 4.4E-5 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_2c00640 64e07940387e2f55b448f050cc424b83 237 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 58 74 4.4E-5 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_2c00640 64e07940387e2f55b448f050cc424b83 237 Gene3D G3DSA:1.20.120.530 87 223 6.3E-21 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal VAPA_2c00640 64e07940387e2f55b448f050cc424b83 237 Gene3D G3DSA:1.10.10.10 22 83 3.1E-18 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_2c00640 64e07940387e2f55b448f050cc424b83 237 SMART SM00895 94 216 5.1E-14 T 12-10-2018 IPR011711 GntR, C-terminal VAPA_2c00640 64e07940387e2f55b448f050cc424b83 237 SMART SM00345 26 84 1.3E-10 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_2c00640 64e07940387e2f55b448f050cc424b83 237 Pfam PF07729 FCD domain 94 215 3.0E-17 T 12-10-2018 IPR011711 GntR, C-terminal VAPA_2c00640 64e07940387e2f55b448f050cc424b83 237 Pfam PF00392 Bacterial regulatory proteins, gntR family 24 83 4.2E-16 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_2c00640 64e07940387e2f55b448f050cc424b83 237 SUPERFAMILY SSF48008 90 223 1.67E-20 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal VAPA_2c00640 64e07940387e2f55b448f050cc424b83 237 SUPERFAMILY SSF46785 25 88 9.79E-15 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c27240 5011621fbb6135ae4e53c6198079a21d 395 Pfam PF01610 Transposase 297 394 3.6E-10 T 12-10-2018 IPR002560 Transposase IS204/IS1001/IS1096/IS1165, DDE domain VAPA_1c27240 5011621fbb6135ae4e53c6198079a21d 395 Pfam PF00487 Fatty acid desaturase 15 238 4.9E-15 T 12-10-2018 IPR005804 Fatty acid desaturase domain GO:0006629 VAPA_2c08700 4cbcb2447e3bfc2df3db12f8408cb1ff 911 SMART SM00862 36 114 1.1E-18 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 VAPA_2c08700 4cbcb2447e3bfc2df3db12f8408cb1ff 911 Gene3D G3DSA:1.10.10.10 14 123 3.0E-21 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_2c08700 4cbcb2447e3bfc2df3db12f8408cb1ff 911 Pfam PF00486 Transcriptional regulatory protein, C terminal 36 114 7.7E-16 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 VAPA_2c08700 4cbcb2447e3bfc2df3db12f8408cb1ff 911 PRINTS PR00364 Disease resistance protein signature 343 357 1.1E-7 T 12-10-2018 VAPA_2c08700 4cbcb2447e3bfc2df3db12f8408cb1ff 911 PRINTS PR00364 Disease resistance protein signature 169 184 1.1E-7 T 12-10-2018 VAPA_2c08700 4cbcb2447e3bfc2df3db12f8408cb1ff 911 PRINTS PR00364 Disease resistance protein signature 237 251 1.1E-7 T 12-10-2018 VAPA_2c08700 4cbcb2447e3bfc2df3db12f8408cb1ff 911 SUPERFAMILY SSF46894 18 115 2.01E-16 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 VAPA_2c08700 4cbcb2447e3bfc2df3db12f8408cb1ff 911 Gene3D G3DSA:3.40.50.300 141 286 1.9E-17 T 12-10-2018 VAPA_2c08700 4cbcb2447e3bfc2df3db12f8408cb1ff 911 SUPERFAMILY SSF52540 140 411 1.89E-20 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c45810 c7c57bcd31b5a6fbe7ff826f5a6cbf87 220 Pfam PF00440 Bacterial regulatory proteins, tetR family 28 74 2.1E-11 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 VAPA_1c45810 c7c57bcd31b5a6fbe7ff826f5a6cbf87 220 SUPERFAMILY SSF48498 104 220 3.26E-17 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily VAPA_1c45810 c7c57bcd31b5a6fbe7ff826f5a6cbf87 220 Pfam PF13305 WHG domain 108 197 5.3E-19 T 12-10-2018 IPR025996 WHG domain VAPA_1c45810 c7c57bcd31b5a6fbe7ff826f5a6cbf87 220 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 28 41 2.8E-5 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 VAPA_1c45810 c7c57bcd31b5a6fbe7ff826f5a6cbf87 220 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 49 72 2.8E-5 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 VAPA_1c45810 c7c57bcd31b5a6fbe7ff826f5a6cbf87 220 SUPERFAMILY SSF46689 17 87 2.67E-13 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 VAPA_1c45810 c7c57bcd31b5a6fbe7ff826f5a6cbf87 220 Gene3D G3DSA:1.10.357.10 12 220 1.9E-51 T 12-10-2018 VAPA_1c48660 ec77f3dd399c4a5aae4a014d6e640235 389 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 123 220 4.3E-20 T 12-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 VAPA_1c48660 ec77f3dd399c4a5aae4a014d6e640235 389 Gene3D G3DSA:1.20.140.10 240 386 3.4E-42 T 12-10-2018 VAPA_1c48660 ec77f3dd399c4a5aae4a014d6e640235 389 SUPERFAMILY SSF56645 1 247 3.27E-61 T 12-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 VAPA_1c48660 ec77f3dd399c4a5aae4a014d6e640235 389 Gene3D G3DSA:1.10.540.10 1 120 3.6E-30 T 12-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 VAPA_1c48660 ec77f3dd399c4a5aae4a014d6e640235 389 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 118 6.7E-25 T 12-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 VAPA_1c48660 ec77f3dd399c4a5aae4a014d6e640235 389 Gene3D G3DSA:2.40.110.10 122 239 5.3E-30 T 12-10-2018 VAPA_1c48660 ec77f3dd399c4a5aae4a014d6e640235 389 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 234 381 1.3E-38 T 12-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 VAPA_1c48660 ec77f3dd399c4a5aae4a014d6e640235 389 SUPERFAMILY SSF47203 232 387 2.42E-47 T 12-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 VAPA_1c48660 ec77f3dd399c4a5aae4a014d6e640235 389 PIRSF PIRSF016578 128 386 3.5E-12 T 12-10-2018 VAPA_1c48660 ec77f3dd399c4a5aae4a014d6e640235 389 PIRSF PIRSF016578 2 108 0.15 T 12-10-2018 VAPA_1c05910 9e09f4f5d77d3269e19af1e6b5d5936d 348 Pfam PF12974 ABC transporter, phosphonate, periplasmic substrate-binding protein 43 294 1.9E-41 T 12-10-2018 VAPA_1c05910 9e09f4f5d77d3269e19af1e6b5d5936d 348 Gene3D G3DSA:3.40.190.10 126 238 1.0E-52 T 12-10-2018 VAPA_1c05910 9e09f4f5d77d3269e19af1e6b5d5936d 348 TIGRFAM TIGR01098 3A0109s03R: phosphate/phosphite/phosphonate ABC transporter, periplasmic binding protein 8 261 8.5E-41 T 12-10-2018 IPR005770 Phosphate/phosphite/phosphonate ABC transporter, periplasmic binding protein GO:0043190|GO:0055085 VAPA_1c05910 9e09f4f5d77d3269e19af1e6b5d5936d 348 Gene3D G3DSA:3.40.190.10 42 266 1.0E-52 T 12-10-2018 VAPA_1c05910 9e09f4f5d77d3269e19af1e6b5d5936d 348 SUPERFAMILY SSF53850 62 254 1.09E-18 T 12-10-2018 VAPA_2c12310 e746e88e6b80da8584dfe80dabbb9e67 260 Gene3D G3DSA:3.40.50.300 1 247 3.3E-65 T 12-10-2018 VAPA_2c12310 e746e88e6b80da8584dfe80dabbb9e67 260 SMART SM00382 26 224 6.9E-9 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_2c12310 e746e88e6b80da8584dfe80dabbb9e67 260 Pfam PF00005 ABC transporter 18 175 4.4E-29 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_2c12310 e746e88e6b80da8584dfe80dabbb9e67 260 SUPERFAMILY SSF52540 1 246 3.43E-67 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_2c12310 e746e88e6b80da8584dfe80dabbb9e67 260 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 224 246 2.0E-11 T 12-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal VAPA_2c11210 5891a6f3317f2afd22cfa2475d8895c2 658 Pfam PF01968 Hydantoinase/oxoprolinase 211 494 1.8E-62 T 12-10-2018 IPR002821 Hydantoinase A/oxoprolinase GO:0016787 Reactome: R-HSA-174403|Reactome: R-HSA-5578998 VAPA_2c11210 5891a6f3317f2afd22cfa2475d8895c2 658 Pfam PF05378 Hydantoinase/oxoprolinase N-terminal region 11 189 1.6E-40 T 12-10-2018 IPR008040 Hydantoinaseoxoprolinase, N-terminal Reactome: R-HSA-174403|Reactome: R-HSA-5578998 VAPA_2c11210 5891a6f3317f2afd22cfa2475d8895c2 658 Gene3D G3DSA:3.30.420.40 10 78 2.4E-5 T 12-10-2018 VAPA_2c11210 5891a6f3317f2afd22cfa2475d8895c2 658 Gene3D G3DSA:3.30.420.150 272 352 1.4E-5 T 12-10-2018 VAPA_2c11210 5891a6f3317f2afd22cfa2475d8895c2 658 SUPERFAMILY SSF53067 10 488 4.32E-11 T 12-10-2018 VAPA_1c22640 8ff2a30714c2352af45a109eb5e7d9a6 228 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 17 218 1.4E-36 T 12-10-2018 IPR011234 Fumarylacetoacetase-like, C-terminal GO:0003824 VAPA_1c22640 8ff2a30714c2352af45a109eb5e7d9a6 228 Gene3D G3DSA:3.90.850.10 14 224 1.7E-43 T 12-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 VAPA_1c22640 8ff2a30714c2352af45a109eb5e7d9a6 228 TIGRFAM TIGR02305 HpaG-N-term: 4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase, N-terminal subunit 15 216 6.9E-70 T 12-10-2018 IPR012686 4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase, N-terminal subunit GO:0008704|GO:0018800 KEGG: 00350+5.3.3.10+4.1.1.68 VAPA_1c22640 8ff2a30714c2352af45a109eb5e7d9a6 228 SUPERFAMILY SSF56529 14 220 7.2E-46 T 12-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 VAPA_1c38200 74872585bb9d8d741d4fdddb5bdf0dfd 411 SUPERFAMILY SSF103473 3 399 1.24E-50 T 12-10-2018 IPR036259 MFS transporter superfamily VAPA_1c38200 74872585bb9d8d741d4fdddb5bdf0dfd 411 Pfam PF07690 Major Facilitator Superfamily 22 307 1.2E-17 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 VAPA_1c38200 74872585bb9d8d741d4fdddb5bdf0dfd 411 Gene3D G3DSA:1.20.1250.20 6 198 9.5E-19 T 12-10-2018 VAPA_1c38200 74872585bb9d8d741d4fdddb5bdf0dfd 411 Gene3D G3DSA:1.20.1250.20 213 404 6.3E-16 T 12-10-2018 VAPA_2c04040 2e9fbe9342b3f1d55fea8f98b36858ba 142 SUPERFAMILY SSF52402 1 142 3.52E-33 T 12-10-2018 VAPA_2c04040 2e9fbe9342b3f1d55fea8f98b36858ba 142 Gene3D G3DSA:3.40.50.620 1 142 6.6E-35 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold VAPA_2c04040 2e9fbe9342b3f1d55fea8f98b36858ba 142 PRINTS PR01438 Universal stress protein signature 120 142 3.9E-10 T 12-10-2018 IPR006015 Universal stress protein A VAPA_2c04040 2e9fbe9342b3f1d55fea8f98b36858ba 142 PRINTS PR01438 Universal stress protein signature 102 114 3.9E-10 T 12-10-2018 IPR006015 Universal stress protein A VAPA_2c04040 2e9fbe9342b3f1d55fea8f98b36858ba 142 Pfam PF00582 Universal stress protein family 2 142 8.3E-31 T 12-10-2018 IPR006016 UspA VAPA_1c04750 32ec28d16ae5dfdb40dd3e4c08e55c93 344 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 233 315 2.4E-25 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 VAPA_1c04750 32ec28d16ae5dfdb40dd3e4c08e55c93 344 ProSitePatterns PS00211 ABC transporters family signature. 156 170 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_1c04750 32ec28d16ae5dfdb40dd3e4c08e55c93 344 SMART SM00382 41 233 1.9E-14 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c04750 32ec28d16ae5dfdb40dd3e4c08e55c93 344 Pfam PF00005 ABC transporter 34 183 3.5E-30 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c04750 32ec28d16ae5dfdb40dd3e4c08e55c93 344 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 235 296 3.4E-18 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 VAPA_1c04750 32ec28d16ae5dfdb40dd3e4c08e55c93 344 SUPERFAMILY SSF52540 7 255 4.07E-68 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c04750 32ec28d16ae5dfdb40dd3e4c08e55c93 344 Gene3D G3DSA:3.40.50.300 4 322 1.9E-90 T 12-10-2018 VAPA_1c42340 d5bb2b76e1061626fe4c4d309fba8abd 343 SMART SM01329 4 336 2.2E-157 T 12-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 VAPA_1c42340 d5bb2b76e1061626fe4c4d309fba8abd 343 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 8 336 1.7E-96 T 12-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 VAPA_1c42340 d5bb2b76e1061626fe4c4d309fba8abd 343 SUPERFAMILY SSF53659 5 340 9.22E-115 T 12-10-2018 VAPA_1c42340 d5bb2b76e1061626fe4c4d309fba8abd 343 Gene3D G3DSA:3.40.718.10 5 343 1.5E-125 T 12-10-2018 VAPA_1c42340 d5bb2b76e1061626fe4c4d309fba8abd 343 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 232 251 - T 12-10-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 VAPA_1c48610 4d8f6e0acbd94099e014f04c4988cb9f 214 Pfam PF01323 DSBA-like thioredoxin domain 4 188 5.1E-26 T 12-10-2018 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590|Reactome: R-HSA-9033241 VAPA_1c48610 4d8f6e0acbd94099e014f04c4988cb9f 214 Gene3D G3DSA:3.40.30.10 3 192 1.1E-43 T 12-10-2018 VAPA_1c48610 4d8f6e0acbd94099e014f04c4988cb9f 214 SUPERFAMILY SSF52833 4 189 1.86E-30 T 12-10-2018 IPR036249 Thioredoxin-like superfamily VAPA_1c48610 4d8f6e0acbd94099e014f04c4988cb9f 214 PIRSF PIRSF006386 1 198 1.4E-35 T 12-10-2018 IPR014440 HCCA isomerase/glutathione S-transferase kappa Reactome: R-HSA-156590|Reactome: R-HSA-9033241 VAPA_1c15310 cdbd6ceff6a5986e23fa6c2ca22c49ce 298 SMART SM00530 40 95 3.8E-10 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 VAPA_1c15310 cdbd6ceff6a5986e23fa6c2ca22c49ce 298 SUPERFAMILY SSF47413 35 94 5.9E-14 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 VAPA_1c15310 cdbd6ceff6a5986e23fa6c2ca22c49ce 298 Pfam PF13560 Helix-turn-helix domain 37 98 2.4E-13 T 12-10-2018 VAPA_1c15310 cdbd6ceff6a5986e23fa6c2ca22c49ce 298 Gene3D G3DSA:1.10.260.40 33 102 1.0E-13 T 12-10-2018 VAPA_1c39080 443d242b73cdd9e57d1223e60ebad7fd 273 Gene3D G3DSA:3.40.190.10 114 222 4.3E-82 T 12-10-2018 VAPA_1c39080 443d242b73cdd9e57d1223e60ebad7fd 273 PIRSF PIRSF002854 1 271 3.2E-78 T 12-10-2018 IPR004872 Lipoprotein NlpA family VAPA_1c39080 443d242b73cdd9e57d1223e60ebad7fd 273 Pfam PF03180 NLPA lipoprotein 35 270 1.1E-74 T 12-10-2018 IPR004872 Lipoprotein NlpA family VAPA_1c39080 443d242b73cdd9e57d1223e60ebad7fd 273 SUPERFAMILY SSF53850 35 271 2.6E-68 T 12-10-2018 VAPA_1c39080 443d242b73cdd9e57d1223e60ebad7fd 273 Gene3D G3DSA:3.40.190.10 52 265 4.3E-82 T 12-10-2018 VAPA_2c11580 6acb2cf43f5942f5eeb30b948b3ba855 263 PIRSF PIRSF037116 1 263 3.9E-138 T 12-10-2018 IPR012700 Phosphonate C-P lyase system, PhnK VAPA_2c11580 6acb2cf43f5942f5eeb30b948b3ba855 263 Gene3D G3DSA:3.40.50.300 9 263 7.5E-69 T 12-10-2018 VAPA_2c11580 6acb2cf43f5942f5eeb30b948b3ba855 263 SMART SM00382 36 234 1.2E-14 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_2c11580 6acb2cf43f5942f5eeb30b948b3ba855 263 Pfam PF00005 ABC transporter 27 185 1.1E-27 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_2c11580 6acb2cf43f5942f5eeb30b948b3ba855 263 TIGRFAM TIGR02323 CP_lyasePhnK: phosphonate C-P lyase system protein PhnK 10 261 1.4E-113 T 12-10-2018 IPR012700 Phosphonate C-P lyase system, PhnK VAPA_2c11580 6acb2cf43f5942f5eeb30b948b3ba855 263 SUPERFAMILY SSF52540 10 259 2.81E-59 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_2c11580 6acb2cf43f5942f5eeb30b948b3ba855 263 ProSitePatterns PS00211 ABC transporters family signature. 157 171 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_1c36470 648a3e56e854bb0088822ab38dc1c055 296 SUPERFAMILY SSF161098 9 281 3.79E-39 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c36470 648a3e56e854bb0088822ab38dc1c055 296 Gene3D G3DSA:1.10.3720.10 9 293 3.8E-35 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c36470 648a3e56e854bb0088822ab38dc1c055 296 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 89 285 2.1E-11 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 VAPA_1c47860 3de1aeed07b0bab89c338b8434a0bf91 293 SUPERFAMILY SSF50800 9 274 2.2E-14 T 12-10-2018 IPR011037 Pyruvate kinase-like, insert domain superfamily VAPA_1c47860 3de1aeed07b0bab89c338b8434a0bf91 293 SUPERFAMILY SSF141673 12 142 3.79E-39 T 12-10-2018 VAPA_1c47860 3de1aeed07b0bab89c338b8434a0bf91 293 Pfam PF03473 MOSC domain 155 286 1.2E-20 T 12-10-2018 IPR005302 Molybdenum cofactor sulfurase, C-terminal GO:0003824|GO:0030151|GO:0030170 VAPA_1c47860 3de1aeed07b0bab89c338b8434a0bf91 293 Pfam PF03476 MOSC N-terminal beta barrel domain 10 124 1.3E-34 T 12-10-2018 IPR005303 MOSC, N-terminal beta barrel KEGG: 00790+2.8.1.9|MetaCyc: PWY-5963 VAPA_1c32360 d077b97d56c66dd896e7c52f6acd8790 187 Gene3D G3DSA:3.40.50.300 7 185 6.2E-14 T 12-10-2018 VAPA_1c32360 d077b97d56c66dd896e7c52f6acd8790 187 SUPERFAMILY SSF52540 5 181 2.21E-11 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c14800 51eb55d039ded76c379832fd5e62d4bc 60 SUPERFAMILY SSF57829 2 55 1.46E-17 T 12-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 VAPA_1c14800 51eb55d039ded76c379832fd5e62d4bc 60 Pfam PF01783 Ribosomal L32p protein family 2 55 9.7E-20 T 12-10-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 VAPA_1c14800 51eb55d039ded76c379832fd5e62d4bc 60 Hamap MF_00340 50S ribosomal protein L32 [rpmF]. 1 54 17.158 T 12-10-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 VAPA_1c14800 51eb55d039ded76c379832fd5e62d4bc 60 TIGRFAM TIGR01031 rpmF_bact: ribosomal protein bL32 2 55 1.5E-20 T 12-10-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 VAPA_2c00970 9fdad3bb9d1e28c6833eff30c71dba63 301 Gene3D G3DSA:1.10.260.40 11 79 7.5E-12 T 12-10-2018 VAPA_2c00970 9fdad3bb9d1e28c6833eff30c71dba63 301 Pfam PF13560 Helix-turn-helix domain 16 72 2.4E-9 T 12-10-2018 VAPA_2c00970 9fdad3bb9d1e28c6833eff30c71dba63 301 SUPERFAMILY SSF47413 14 78 9.65E-12 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 VAPA_2c00970 9fdad3bb9d1e28c6833eff30c71dba63 301 SMART SM00530 20 74 8.2E-8 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 VAPA_1c14320 c27a0314c847f233f5fb11553364413c 89 Pfam PF10041 Uncharacterized conserved protein (DUF2277) 2 78 5.0E-34 T 12-10-2018 IPR018735 Protein of unknown function DUF2277 VAPA_1c35260 954f8e5f4b0b835f547851c364904dea 223 SUPERFAMILY SSF161098 14 202 1.24E-46 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c35260 954f8e5f4b0b835f547851c364904dea 223 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 35 216 4.5E-23 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 VAPA_1c35260 954f8e5f4b0b835f547851c364904dea 223 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 14 111 6.2E-30 T 12-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 VAPA_1c35260 954f8e5f4b0b835f547851c364904dea 223 Gene3D G3DSA:1.10.3720.10 3 217 5.7E-56 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c18420 b973065c54e4c42b239fe9dd30f2f4c9 305 SUPERFAMILY SSF46785 4 110 2.88E-20 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c18420 b973065c54e4c42b239fe9dd30f2f4c9 305 Gene3D G3DSA:3.40.190.290 93 302 5.0E-29 T 12-10-2018 VAPA_1c18420 b973065c54e4c42b239fe9dd30f2f4c9 305 Gene3D G3DSA:1.10.10.10 4 91 5.6E-21 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c18420 b973065c54e4c42b239fe9dd30f2f4c9 305 SUPERFAMILY SSF53850 91 301 8.53E-33 T 12-10-2018 VAPA_1c18420 b973065c54e4c42b239fe9dd30f2f4c9 305 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 65 7.5E-17 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c18420 b973065c54e4c42b239fe9dd30f2f4c9 305 Pfam PF03466 LysR substrate binding domain 90 295 4.8E-26 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_1c27880 14b6a324ed8db6cdfbe8be61c8d48635 306 Gene3D G3DSA:3.40.190.290 93 298 1.0E-47 T 12-10-2018 VAPA_1c27880 14b6a324ed8db6cdfbe8be61c8d48635 306 SUPERFAMILY SSF53850 92 302 8.87E-35 T 12-10-2018 VAPA_1c27880 14b6a324ed8db6cdfbe8be61c8d48635 306 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 65 2.1E-12 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c27880 14b6a324ed8db6cdfbe8be61c8d48635 306 SUPERFAMILY SSF46785 4 113 1.91E-17 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c27880 14b6a324ed8db6cdfbe8be61c8d48635 306 Gene3D G3DSA:1.10.10.10 4 90 1.2E-19 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c27880 14b6a324ed8db6cdfbe8be61c8d48635 306 Pfam PF03466 LysR substrate binding domain 90 299 6.6E-33 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_1c48370 dde362158491db94accf7693b966f01e 309 Gene3D G3DSA:3.30.160.390 1 89 1.3E-18 T 12-10-2018 IPR038488 Integrase, DNA-binding domain superfamily VAPA_1c48370 dde362158491db94accf7693b966f01e 309 Gene3D G3DSA:1.10.150.130 94 202 2.3E-18 T 12-10-2018 IPR010998 Integrase/recombinase, N-terminal VAPA_1c48370 dde362158491db94accf7693b966f01e 309 SUPERFAMILY SSF56349 100 240 4.94E-14 T 12-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 VAPA_1c48370 dde362158491db94accf7693b966f01e 309 Pfam PF13356 Arm DNA-binding domain 3 87 2.5E-15 T 12-10-2018 IPR025166 Integrase, DNA-binding domain VAPA_1c32290 743d51c776ce7bf2ff186470f4b44435 247 SUPERFAMILY SSF52540 7 245 2.25E-57 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c32290 743d51c776ce7bf2ff186470f4b44435 247 Pfam PF00005 ABC transporter 24 177 3.1E-28 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c32290 743d51c776ce7bf2ff186470f4b44435 247 SMART SM00382 32 224 0.0055 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c32290 743d51c776ce7bf2ff186470f4b44435 247 Gene3D G3DSA:3.40.50.300 3 247 1.1E-56 T 12-10-2018 VAPA_1c32290 743d51c776ce7bf2ff186470f4b44435 247 TIGRFAM TIGR03411 urea_trans_UrtD: urea ABC transporter, ATP-binding protein UrtD 7 247 8.6E-114 T 12-10-2018 IPR017781 ABC transporter, urea, ATP-binding protein, UrtD VAPA_1c32290 743d51c776ce7bf2ff186470f4b44435 247 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 224 246 4.3E-8 T 12-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal VAPA_1c10900 e12d3f139a9424010ff579f935ab5a2a 291 SUPERFAMILY SSF53850 90 289 4.65E-28 T 12-10-2018 VAPA_1c10900 e12d3f139a9424010ff579f935ab5a2a 291 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 3.0E-24 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c10900 e12d3f139a9424010ff579f935ab5a2a 291 Pfam PF03466 LysR substrate binding domain 87 288 8.1E-27 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_1c10900 e12d3f139a9424010ff579f935ab5a2a 291 Gene3D G3DSA:3.40.190.290 90 289 1.5E-21 T 12-10-2018 VAPA_1c10900 e12d3f139a9424010ff579f935ab5a2a 291 SUPERFAMILY SSF46785 1 86 4.08E-23 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c10900 e12d3f139a9424010ff579f935ab5a2a 291 Gene3D G3DSA:1.10.10.10 1 85 2.0E-27 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c10900 e12d3f139a9424010ff579f935ab5a2a 291 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 2.6E-7 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c10900 e12d3f139a9424010ff579f935ab5a2a 291 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 2.6E-7 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c10900 e12d3f139a9424010ff579f935ab5a2a 291 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 2.6E-7 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c41490 1e3c92701ffdccce11e6f1c4634450d8 513 Gene3D G3DSA:3.60.21.70 139 513 4.4E-117 T 12-10-2018 IPR038607 PhoD-like superfamily VAPA_1c41490 1e3c92701ffdccce11e6f1c4634450d8 513 Pfam PF16655 PhoD-like phosphatase, N-terminal domain 38 133 3.4E-32 T 12-10-2018 IPR032093 Phospholipase D, N-terminal VAPA_1c41490 1e3c92701ffdccce11e6f1c4634450d8 513 Gene3D G3DSA:2.60.40.380 29 136 2.8E-38 T 12-10-2018 IPR008963 Purple acid phosphatase-like, N-terminal GO:0003993|GO:0046872 VAPA_1c41490 1e3c92701ffdccce11e6f1c4634450d8 513 SUPERFAMILY SSF56300 142 418 5.69E-28 T 12-10-2018 VAPA_1c41490 1e3c92701ffdccce11e6f1c4634450d8 513 Pfam PF09423 PhoD-like phosphatase 147 478 2.0E-96 T 12-10-2018 IPR018946 Alkaline phosphatase D-related VAPA_1c04930 653c09e718321dffa34b287ebd5deef4 434 ProSitePatterns PS00808 ADP-glucose pyrophosphorylase signature 1. 27 46 - T 12-10-2018 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622|MetaCyc: PWY-7902 VAPA_1c04930 653c09e718321dffa34b287ebd5deef4 434 SUPERFAMILY SSF51161 316 420 9.84E-16 T 12-10-2018 IPR011004 Trimeric LpxA-like superfamily VAPA_1c04930 653c09e718321dffa34b287ebd5deef4 434 Gene3D G3DSA:2.160.10.10 307 433 3.3E-37 T 12-10-2018 VAPA_1c04930 653c09e718321dffa34b287ebd5deef4 434 TIGRFAM TIGR02091 glgC: glucose-1-phosphate adenylyltransferase 21 403 4.9E-151 T 12-10-2018 IPR011831 Glucose-1-phosphate adenylyltransferase GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622|MetaCyc: PWY-7902 VAPA_1c04930 653c09e718321dffa34b287ebd5deef4 434 Hamap MF_00624 Glucose-1-phosphate adenylyltransferase [glgC]. 18 429 51.234 T 12-10-2018 IPR023049 Glucose-1-phosphate adenylyltransferase GlgC, bacterial GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622|MetaCyc: PWY-7902 VAPA_1c04930 653c09e718321dffa34b287ebd5deef4 434 ProSitePatterns PS00810 ADP-glucose pyrophosphorylase signature 3. 214 224 - T 12-10-2018 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622|MetaCyc: PWY-7902 VAPA_1c04930 653c09e718321dffa34b287ebd5deef4 434 ProSitePatterns PS00809 ADP-glucose pyrophosphorylase signature 2. 114 122 - T 12-10-2018 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622|MetaCyc: PWY-7902 VAPA_1c04930 653c09e718321dffa34b287ebd5deef4 434 Pfam PF00483 Nucleotidyl transferase 23 297 2.7E-66 T 12-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 VAPA_1c04930 653c09e718321dffa34b287ebd5deef4 434 SUPERFAMILY SSF53448 19 364 4.93E-73 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases VAPA_1c04930 653c09e718321dffa34b287ebd5deef4 434 Gene3D G3DSA:3.90.550.10 13 306 1.2E-83 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases VAPA_1c11510 deb0444fa3da31c5c0e449526157ce2e 320 Pfam PF02900 Catalytic LigB subunit of aromatic ring-opening dioxygenase 68 316 1.8E-32 T 12-10-2018 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 VAPA_1c11510 deb0444fa3da31c5c0e449526157ce2e 320 SUPERFAMILY SSF53213 63 320 3.4E-83 T 12-10-2018 VAPA_1c11510 deb0444fa3da31c5c0e449526157ce2e 320 PIRSF PIRSF006157 59 320 3.9E-83 T 12-10-2018 IPR014436 Extradiol aromatic ring-opening dioxygenase, DODA-type GO:0008270|GO:0016701|GO:0055114 VAPA_1c11510 deb0444fa3da31c5c0e449526157ce2e 320 Gene3D G3DSA:3.40.830.10 54 320 9.1E-85 T 12-10-2018 VAPA_2c02510 b36ee59021fd45f4b1e8b18a8daf4926 323 PIRSF PIRSF017082 1 323 7.7E-71 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_2c02510 b36ee59021fd45f4b1e8b18a8daf4926 323 Gene3D G3DSA:3.40.190.150 27 313 3.5E-102 T 12-10-2018 VAPA_2c02510 b36ee59021fd45f4b1e8b18a8daf4926 323 SUPERFAMILY SSF53850 110 284 1.74E-8 T 12-10-2018 VAPA_2c02510 b36ee59021fd45f4b1e8b18a8daf4926 323 Gene3D G3DSA:3.40.190.10 125 248 3.5E-102 T 12-10-2018 VAPA_2c02510 b36ee59021fd45f4b1e8b18a8daf4926 323 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 47 319 7.8E-82 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_2c12230 02e12114e88fa0dba27791c6494bc35e 284 Pfam PF02653 Branched-chain amino acid transport system / permease component 10 273 8.6E-40 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 VAPA_1c33080 4483cd2cf3fc4641eb2eaf360839c339 325 Gene3D G3DSA:3.40.190.10 131 250 3.5E-90 T 12-10-2018 VAPA_1c33080 4483cd2cf3fc4641eb2eaf360839c339 325 PIRSF PIRSF017082 1 323 4.1E-64 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c33080 4483cd2cf3fc4641eb2eaf360839c339 325 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 53 321 8.0E-64 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c33080 4483cd2cf3fc4641eb2eaf360839c339 325 SUPERFAMILY SSF53850 104 280 2.53E-9 T 12-10-2018 VAPA_1c33080 4483cd2cf3fc4641eb2eaf360839c339 325 Gene3D G3DSA:3.40.190.150 33 314 3.5E-90 T 12-10-2018 VAPA_2c01930 267b2b71964eaee8184bfd18f22991ab 155 SUPERFAMILY SSF46785 11 147 2.18E-25 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_2c01930 267b2b71964eaee8184bfd18f22991ab 155 SMART SM00347 33 131 2.7E-14 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 VAPA_2c01930 267b2b71964eaee8184bfd18f22991ab 155 Pfam PF01047 MarR family 41 89 9.5E-11 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 VAPA_2c01930 267b2b71964eaee8184bfd18f22991ab 155 Gene3D G3DSA:1.10.10.10 6 152 2.9E-30 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_2c01930 267b2b71964eaee8184bfd18f22991ab 155 PRINTS PR00598 Bacterial regulatory protein MarR family signature 57 73 7.5E-5 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 VAPA_2c01930 267b2b71964eaee8184bfd18f22991ab 155 PRINTS PR00598 Bacterial regulatory protein MarR family signature 74 89 7.5E-5 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 VAPA_2c01930 267b2b71964eaee8184bfd18f22991ab 155 PRINTS PR00598 Bacterial regulatory protein MarR family signature 121 141 7.5E-5 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 VAPA_1c25500 5faa408980f917082060328effeddc78 592 Gene3D G3DSA:3.90.480.20 333 428 1.3E-9 T 12-10-2018 VAPA_1c25500 5faa408980f917082060328effeddc78 592 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 444 583 1.1E-10 T 12-10-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 VAPA_1c25500 5faa408980f917082060328effeddc78 592 Gene3D G3DSA:3.30.413.10 437 589 1.3E-30 T 12-10-2018 VAPA_1c25500 5faa408980f917082060328effeddc78 592 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 142 282 3.0E-34 T 12-10-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 VAPA_1c25500 5faa408980f917082060328effeddc78 592 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 53 82 6.2E-5 T 12-10-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 VAPA_1c25500 5faa408980f917082060328effeddc78 592 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 374 428 4.5E-15 T 12-10-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 VAPA_1c25500 5faa408980f917082060328effeddc78 592 SUPERFAMILY SSF55124 338 451 6.05E-21 T 12-10-2018 IPR036136 Nitrite/Sulfite reductase ferredoxin-like domain superfamily GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 VAPA_1c25500 5faa408980f917082060328effeddc78 592 SUPERFAMILY SSF56014 143 305 1.44E-43 T 12-10-2018 VAPA_1c25500 5faa408980f917082060328effeddc78 592 Gene3D G3DSA:3.90.480.20 7 158 2.4E-16 T 12-10-2018 VAPA_1c25500 5faa408980f917082060328effeddc78 592 SUPERFAMILY SSF55124 1 149 7.56E-19 T 12-10-2018 IPR036136 Nitrite/Sulfite reductase ferredoxin-like domain superfamily GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 VAPA_1c25500 5faa408980f917082060328effeddc78 592 Gene3D G3DSA:3.30.413.10 159 303 2.9E-26 T 12-10-2018 VAPA_1c25500 5faa408980f917082060328effeddc78 592 SUPERFAMILY SSF56014 439 582 9.81E-39 T 12-10-2018 VAPA_1c54150 b72446105bef8b5a0aed5cf93c17ff54 295 Pfam PF07722 Peptidase C26 11 239 5.9E-52 T 12-10-2018 IPR011697 Peptidase C26 GO:0016787 Reactome: R-HSA-6798695 VAPA_1c54150 b72446105bef8b5a0aed5cf93c17ff54 295 SUPERFAMILY SSF52317 32 263 1.25E-35 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like VAPA_1c54150 b72446105bef8b5a0aed5cf93c17ff54 295 Gene3D G3DSA:3.40.50.880 7 270 2.0E-63 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like VAPA_1c33340 599b544458ee3085e03b769975b3a53d 433 Gene3D G3DSA:3.65.10.10 21 232 9.1E-110 T 12-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 VAPA_1c33340 599b544458ee3085e03b769975b3a53d 433 Gene3D G3DSA:3.65.10.10 6 427 9.1E-110 T 12-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 VAPA_1c33340 599b544458ee3085e03b769975b3a53d 433 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 7 420 1.9E-50 T 12-10-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 VAPA_1c33340 599b544458ee3085e03b769975b3a53d 433 SUPERFAMILY SSF55205 1 430 1.64E-89 T 12-10-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 VAPA_1c29000 96bac20fb35d66ebaf55f8128f260f5a 481 Pfam PF13396 Phospholipase_D-nuclease N-terminal 24 61 3.3E-7 T 12-10-2018 IPR027379 Cardiolipin synthase N-terminal VAPA_1c29000 96bac20fb35d66ebaf55f8128f260f5a 481 TIGRFAM TIGR04265 bac_cardiolipin: cardiolipin synthase 16 481 2.1E-118 T 12-10-2018 IPR022924 Cardiolipin synthase GO:0008808|GO:0016780|GO:0032049 VAPA_1c29000 96bac20fb35d66ebaf55f8128f260f5a 481 Gene3D G3DSA:3.30.870.10 115 300 9.7E-43 T 12-10-2018 VAPA_1c29000 96bac20fb35d66ebaf55f8128f260f5a 481 Pfam PF13091 PLD-like domain 135 276 5.3E-13 T 12-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 VAPA_1c29000 96bac20fb35d66ebaf55f8128f260f5a 481 Pfam PF13091 PLD-like domain 325 450 1.9E-27 T 12-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 VAPA_1c29000 96bac20fb35d66ebaf55f8128f260f5a 481 SUPERFAMILY SSF56024 268 457 2.47E-46 T 12-10-2018 VAPA_1c29000 96bac20fb35d66ebaf55f8128f260f5a 481 SMART SM00155 396 423 1.9E-4 T 12-10-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 VAPA_1c29000 96bac20fb35d66ebaf55f8128f260f5a 481 SMART SM00155 217 244 0.068 T 12-10-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 VAPA_1c29000 96bac20fb35d66ebaf55f8128f260f5a 481 Gene3D G3DSA:3.30.870.10 301 479 1.3E-30 T 12-10-2018 VAPA_1c29000 96bac20fb35d66ebaf55f8128f260f5a 481 SUPERFAMILY SSF56024 93 314 9.73E-50 T 12-10-2018 VAPA_2c08720 e5bbb1aeccafb9ce135298d11dbe883a 206 SUPERFAMILY SSF46894 136 204 4.42E-18 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 VAPA_2c08720 e5bbb1aeccafb9ce135298d11dbe883a 206 SMART SM00421 141 198 3.5E-18 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_2c08720 e5bbb1aeccafb9ce135298d11dbe883a 206 Pfam PF00196 Bacterial regulatory proteins, luxR family 144 198 5.3E-17 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_2c08720 e5bbb1aeccafb9ce135298d11dbe883a 206 SUPERFAMILY SSF52172 5 122 9.51E-7 T 12-10-2018 IPR011006 CheY-like superfamily VAPA_2c08720 e5bbb1aeccafb9ce135298d11dbe883a 206 Gene3D G3DSA:3.40.50.12740 9 204 1.3E-29 T 12-10-2018 VAPA_2c08720 e5bbb1aeccafb9ce135298d11dbe883a 206 ProSitePatterns PS00622 LuxR-type HTH domain signature. 158 185 - T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_2c08720 e5bbb1aeccafb9ce135298d11dbe883a 206 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 174 186 8.8E-11 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_2c08720 e5bbb1aeccafb9ce135298d11dbe883a 206 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 144 158 8.8E-11 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_2c08720 e5bbb1aeccafb9ce135298d11dbe883a 206 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 158 174 8.8E-11 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_1c02130 95b0477474c82bb0877d847b3740c669 257 Gene3D G3DSA:3.40.50.80 101 253 6.0E-43 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain VAPA_1c02130 95b0477474c82bb0877d847b3740c669 257 SUPERFAMILY SSF63380 6 99 2.33E-23 T 12-10-2018 IPR017938 Riboflavin synthase-like beta-barrel VAPA_1c02130 95b0477474c82bb0877d847b3740c669 257 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 136 145 7.7E-6 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 VAPA_1c02130 95b0477474c82bb0877d847b3740c669 257 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 51 58 7.7E-6 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 VAPA_1c02130 95b0477474c82bb0877d847b3740c669 257 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 111 130 7.7E-6 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 VAPA_1c02130 95b0477474c82bb0877d847b3740c669 257 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 215 223 7.7E-6 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 VAPA_1c02130 95b0477474c82bb0877d847b3740c669 257 Pfam PF00175 Oxidoreductase NAD-binding domain 113 225 5.1E-8 T 12-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 VAPA_1c02130 95b0477474c82bb0877d847b3740c669 257 Gene3D G3DSA:2.40.30.10 1 96 1.0E-25 T 12-10-2018 VAPA_1c02130 95b0477474c82bb0877d847b3740c669 257 SUPERFAMILY SSF52343 104 254 7.99E-39 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain VAPA_1c02130 95b0477474c82bb0877d847b3740c669 257 Pfam PF00970 Oxidoreductase FAD-binding domain 18 91 1.3E-7 T 12-10-2018 IPR008333 Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain Reactome: R-HSA-1237044 VAPA_1c31890 e4e8654e23e526776668d02cfaa352bf 514 SMART SM00388 267 332 1.1E-8 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 VAPA_1c31890 e4e8654e23e526776668d02cfaa352bf 514 PRINTS PR00344 Bacterial sensor protein C-terminal signature 444 454 6.4E-9 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c31890 e4e8654e23e526776668d02cfaa352bf 514 PRINTS PR00344 Bacterial sensor protein C-terminal signature 426 440 6.4E-9 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c31890 e4e8654e23e526776668d02cfaa352bf 514 PRINTS PR00344 Bacterial sensor protein C-terminal signature 461 479 6.4E-9 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c31890 e4e8654e23e526776668d02cfaa352bf 514 PRINTS PR00344 Bacterial sensor protein C-terminal signature 491 504 6.4E-9 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c31890 e4e8654e23e526776668d02cfaa352bf 514 SUPERFAMILY SSF47384 250 329 6.28E-13 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 VAPA_1c31890 e4e8654e23e526776668d02cfaa352bf 514 Pfam PF00512 His Kinase A (phospho-acceptor) domain 269 329 3.2E-8 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 VAPA_1c31890 e4e8654e23e526776668d02cfaa352bf 514 SUPERFAMILY SSF55874 330 508 1.83E-31 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_1c31890 e4e8654e23e526776668d02cfaa352bf 514 Gene3D G3DSA:1.10.287.130 218 330 5.6E-15 T 12-10-2018 VAPA_1c31890 e4e8654e23e526776668d02cfaa352bf 514 SMART SM00387 389 507 8.1E-28 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase VAPA_1c31890 e4e8654e23e526776668d02cfaa352bf 514 Pfam PF08521 Two-component sensor kinase N-terminal 32 188 1.7E-22 T 12-10-2018 IPR013727 Two-component sensor kinase, N-terminal VAPA_1c31890 e4e8654e23e526776668d02cfaa352bf 514 Gene3D G3DSA:3.30.565.10 331 506 6.9E-31 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_1c31890 e4e8654e23e526776668d02cfaa352bf 514 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 392 505 2.9E-18 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase VAPA_1c41780 0e31db4d78afff6f21c3ea8c862833ca 320 Gene3D G3DSA:3.40.50.1100 62 156 4.4E-84 T 12-10-2018 VAPA_1c41780 0e31db4d78afff6f21c3ea8c862833ca 320 SUPERFAMILY SSF53686 22 316 4.32E-72 T 12-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme VAPA_1c41780 0e31db4d78afff6f21c3ea8c862833ca 320 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 27 311 1.6E-70 T 12-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme VAPA_1c41780 0e31db4d78afff6f21c3ea8c862833ca 320 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 54 67 - T 12-10-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 VAPA_1c41780 0e31db4d78afff6f21c3ea8c862833ca 320 Gene3D G3DSA:3.40.50.1100 26 315 4.4E-84 T 12-10-2018 VAPA_1c14260 9eeefb14f240288189109d9776210ccc 394 SUPERFAMILY SSF55031 188 300 8.24E-32 T 12-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain VAPA_1c14260 9eeefb14f240288189109d9776210ccc 394 PIRSF PIRSF005962 3 394 4.5E-122 T 12-10-2018 IPR017439 Amidohydrolase GO:0016787 VAPA_1c14260 9eeefb14f240288189109d9776210ccc 394 Gene3D G3DSA:3.30.70.360 186 300 2.9E-133 T 12-10-2018 VAPA_1c14260 9eeefb14f240288189109d9776210ccc 394 SUPERFAMILY SSF53187 7 393 6.58E-87 T 12-10-2018 VAPA_1c14260 9eeefb14f240288189109d9776210ccc 394 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 20 381 4.7E-108 T 12-10-2018 IPR017439 Amidohydrolase GO:0016787 VAPA_1c14260 9eeefb14f240288189109d9776210ccc 394 Pfam PF07687 Peptidase dimerisation domain 191 286 1.1E-12 T 12-10-2018 IPR011650 Peptidase M20, dimerisation domain VAPA_1c14260 9eeefb14f240288189109d9776210ccc 394 Pfam PF01546 Peptidase family M20/M25/M40 78 390 2.7E-31 T 12-10-2018 IPR002933 Peptidase M20 GO:0016787 VAPA_1c14260 9eeefb14f240288189109d9776210ccc 394 Gene3D G3DSA:3.40.630.10 20 378 2.9E-133 T 12-10-2018 VAPA_1c34100 74acc719e8dd1183b6777f9a9017bea6 968 Gene3D G3DSA:3.90.1150.10 771 909 4.2E-39 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 VAPA_1c34100 74acc719e8dd1183b6777f9a9017bea6 968 SUPERFAMILY SSF53383 21 448 1.31E-104 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase VAPA_1c34100 74acc719e8dd1183b6777f9a9017bea6 968 TIGRFAM TIGR00461 gcvP: glycine dehydrogenase 21 956 0.0 T 12-10-2018 IPR003437 Glycine dehydrogenase (decarboxylating) GO:0004375|GO:0006544|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 VAPA_1c34100 74acc719e8dd1183b6777f9a9017bea6 968 Gene3D G3DSA:3.40.640.10 100 362 2.5E-105 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 VAPA_1c34100 74acc719e8dd1183b6777f9a9017bea6 968 Gene3D G3DSA:3.40.640.10 530 756 3.5E-57 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 VAPA_1c34100 74acc719e8dd1183b6777f9a9017bea6 968 Pfam PF02347 Glycine cleavage system P-protein 467 742 1.1E-10 T 12-10-2018 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 VAPA_1c34100 74acc719e8dd1183b6777f9a9017bea6 968 Pfam PF02347 Glycine cleavage system P-protein 21 448 7.8E-177 T 12-10-2018 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 VAPA_1c34100 74acc719e8dd1183b6777f9a9017bea6 968 SUPERFAMILY SSF53383 467 957 1.33E-97 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase VAPA_1c34100 74acc719e8dd1183b6777f9a9017bea6 968 Hamap MF_00711 Glycine dehydrogenase (decarboxylating) [gcvP]. 12 962 25.254 T 12-10-2018 IPR003437 Glycine dehydrogenase (decarboxylating) GO:0004375|GO:0006544|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 VAPA_2c06860 2dbc125235c24cdc81bb76fd53eeac1e 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 8.4E-7 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_2c06860 2dbc125235c24cdc81bb76fd53eeac1e 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 8.4E-7 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_2c06860 2dbc125235c24cdc81bb76fd53eeac1e 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 8.4E-7 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_2c06860 2dbc125235c24cdc81bb76fd53eeac1e 299 SUPERFAMILY SSF46785 2 83 8.62E-19 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_2c06860 2dbc125235c24cdc81bb76fd53eeac1e 299 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 64 1.1E-17 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_2c06860 2dbc125235c24cdc81bb76fd53eeac1e 299 Pfam PF03466 LysR substrate binding domain 90 292 2.2E-31 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_2c06860 2dbc125235c24cdc81bb76fd53eeac1e 299 SUPERFAMILY SSF53850 94 296 1.63E-33 T 12-10-2018 VAPA_2c06860 2dbc125235c24cdc81bb76fd53eeac1e 299 Gene3D G3DSA:3.40.190.290 95 297 2.0E-28 T 12-10-2018 VAPA_2c06860 2dbc125235c24cdc81bb76fd53eeac1e 299 Gene3D G3DSA:1.10.10.10 3 94 1.3E-19 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_2c03840 3387bb70112993bf45a5f0c987feb916 502 Pfam PF02885 Glycosyl transferase family, helical bundle domain 100 157 2.8E-9 T 12-10-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 VAPA_2c03840 3387bb70112993bf45a5f0c987feb916 502 PIRSF PIRSF000478 93 501 9.2E-117 T 12-10-2018 IPR000053 Thymidine/pyrimidine-nucleoside phosphorylase GO:0004645|GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 VAPA_2c03840 3387bb70112993bf45a5f0c987feb916 502 Gene3D G3DSA:3.90.1170.30 418 499 2.6E-22 T 12-10-2018 IPR036566 Pyrimidine nucleoside phosphorylase-like, C-terminal domain superfamily GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 VAPA_2c03840 3387bb70112993bf45a5f0c987feb916 502 ProSitePatterns PS00647 Thymidine and pyrimidine-nucleoside phosphorylases signature. 202 217 - T 12-10-2018 IPR017872 Pyrimidine-nucleoside phosphorylase, conserved site GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 VAPA_2c03840 3387bb70112993bf45a5f0c987feb916 502 SUPERFAMILY SSF54680 416 489 1.31E-15 T 12-10-2018 IPR036566 Pyrimidine nucleoside phosphorylase-like, C-terminal domain superfamily GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 VAPA_2c03840 3387bb70112993bf45a5f0c987feb916 502 TIGRFAM TIGR02645 ARCH_P_rylase: putative thymidine phosphorylase 10 495 4.3E-170 T 12-10-2018 IPR013466 Thymidine phosphorylase/AMP phosphorylase GO:0016763 VAPA_2c03840 3387bb70112993bf45a5f0c987feb916 502 SUPERFAMILY SSF47648 95 162 1.31E-12 T 12-10-2018 IPR036320 Glycosyl transferase family 3, N-terminal domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 VAPA_2c03840 3387bb70112993bf45a5f0c987feb916 502 Pfam PF00591 Glycosyl transferase family, a/b domain 168 397 9.2E-13 T 12-10-2018 IPR000312 Glycosyl transferase, family 3 GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 VAPA_2c03840 3387bb70112993bf45a5f0c987feb916 502 SMART SM00941 429 496 1.3E-20 T 12-10-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 VAPA_2c03840 3387bb70112993bf45a5f0c987feb916 502 Gene3D G3DSA:1.20.970.50 101 333 4.1E-105 T 12-10-2018 VAPA_2c03840 3387bb70112993bf45a5f0c987feb916 502 Pfam PF07831 Pyrimidine nucleoside phosphorylase C-terminal domain 429 491 2.2E-9 T 12-10-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 VAPA_2c03840 3387bb70112993bf45a5f0c987feb916 502 SUPERFAMILY SSF52418 163 410 1.44E-67 T 12-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 VAPA_2c03840 3387bb70112993bf45a5f0c987feb916 502 Gene3D G3DSA:3.40.1030.10 159 409 4.1E-105 T 12-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 VAPA_2c03840 3387bb70112993bf45a5f0c987feb916 502 Hamap MF_00703 Putative thymidine phosphorylase. 8 500 58.563 T 12-10-2018 IPR028579 Putative thymidine phosphorylase KEGG: 00240+2.4.2.4|KEGG: 00983+2.4.2.4|MetaCyc: PWY-7181 VAPA_1c34950 0127e437b27e7bcd663aa9ef3217ee8d 497 Hamap MF_00186 Glycerol kinase [glpK]. 1 497 55.591 T 12-10-2018 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 VAPA_1c34950 0127e437b27e7bcd663aa9ef3217ee8d 497 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 359 379 - T 12-10-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 VAPA_1c34950 0127e437b27e7bcd663aa9ef3217ee8d 497 Gene3D G3DSA:3.30.420.40 1 250 2.9E-107 T 12-10-2018 VAPA_1c34950 0127e437b27e7bcd663aa9ef3217ee8d 497 Gene3D G3DSA:3.30.420.40 251 495 5.7E-83 T 12-10-2018 VAPA_1c34950 0127e437b27e7bcd663aa9ef3217ee8d 497 SUPERFAMILY SSF53067 252 495 3.56E-77 T 12-10-2018 VAPA_1c34950 0127e437b27e7bcd663aa9ef3217ee8d 497 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 3 249 2.2E-78 T 12-10-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 VAPA_1c34950 0127e437b27e7bcd663aa9ef3217ee8d 497 TIGRFAM TIGR01311 glycerol_kin: glycerol kinase 3 494 4.6E-213 T 12-10-2018 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 VAPA_1c34950 0127e437b27e7bcd663aa9ef3217ee8d 497 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 258 451 2.3E-62 T 12-10-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 VAPA_1c34950 0127e437b27e7bcd663aa9ef3217ee8d 497 ProSitePatterns PS00933 FGGY family of carbohydrate kinases signature 1. 133 145 - T 12-10-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 VAPA_1c34950 0127e437b27e7bcd663aa9ef3217ee8d 497 PIRSF PIRSF000538 1 497 3.7E-174 T 12-10-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 VAPA_1c34950 0127e437b27e7bcd663aa9ef3217ee8d 497 SUPERFAMILY SSF53067 3 252 3.37E-94 T 12-10-2018 VAPA_1c51840 98e5351177342c28084339b789b284b6 599 TIGRFAM TIGR00680 kdpA: K+-transporting ATPase, A subunit 241 596 3.0E-165 T 12-10-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 VAPA_1c51840 98e5351177342c28084339b789b284b6 599 Pfam PF03814 Potassium-transporting ATPase A subunit 11 595 3.6E-240 T 12-10-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 VAPA_1c51840 98e5351177342c28084339b789b284b6 599 Hamap MF_00275 Potassium-transporting ATPase potassium-binding subunit [kdpA]. 2 597 35.868 T 12-10-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 VAPA_1c51840 98e5351177342c28084339b789b284b6 599 PIRSF PIRSF001294 1 599 1.8E-237 T 12-10-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 VAPA_2c02760 447d3d5b0cd88e09b0558ebefccc407c 299 Gene3D G3DSA:3.40.190.10 96 291 3.6E-43 T 12-10-2018 VAPA_2c02760 447d3d5b0cd88e09b0558ebefccc407c 299 Gene3D G3DSA:3.40.190.10 166 270 3.6E-43 T 12-10-2018 VAPA_2c02760 447d3d5b0cd88e09b0558ebefccc407c 299 Pfam PF03466 LysR substrate binding domain 90 295 1.8E-34 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_2c02760 447d3d5b0cd88e09b0558ebefccc407c 299 SUPERFAMILY SSF46785 5 89 4.79E-22 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_2c02760 447d3d5b0cd88e09b0558ebefccc407c 299 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 64 1.1E-20 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_2c02760 447d3d5b0cd88e09b0558ebefccc407c 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 53 4.3E-7 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_2c02760 447d3d5b0cd88e09b0558ebefccc407c 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 32 42 4.3E-7 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_2c02760 447d3d5b0cd88e09b0558ebefccc407c 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 21 32 4.3E-7 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_2c02760 447d3d5b0cd88e09b0558ebefccc407c 299 Gene3D G3DSA:1.10.10.10 4 89 4.0E-26 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_2c02760 447d3d5b0cd88e09b0558ebefccc407c 299 SUPERFAMILY SSF53850 91 297 3.62E-34 T 12-10-2018 VAPA_1c54640 20acba34452ac2db5e4a3ff12f060eea 442 TIGRFAM TIGR01197 nramp: metal ion transporter, metal ion (Mn2+/Fe2+) transporter (Nramp) family 32 406 2.3E-109 T 12-10-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 VAPA_1c54640 20acba34452ac2db5e4a3ff12f060eea 442 Hamap MF_00221 Divalent metal cation transporter MntH [mntH]. 25 438 37.607 T 12-10-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 VAPA_1c54640 20acba34452ac2db5e4a3ff12f060eea 442 Pfam PF01566 Natural resistance-associated macrophage protein 54 412 3.4E-134 T 12-10-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 VAPA_1c54640 20acba34452ac2db5e4a3ff12f060eea 442 PRINTS PR00447 Natural resistance-associated macrophage protein signature 218 241 2.5E-53 T 12-10-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 VAPA_1c54640 20acba34452ac2db5e4a3ff12f060eea 442 PRINTS PR00447 Natural resistance-associated macrophage protein signature 166 187 2.5E-53 T 12-10-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 VAPA_1c54640 20acba34452ac2db5e4a3ff12f060eea 442 PRINTS PR00447 Natural resistance-associated macrophage protein signature 141 160 2.5E-53 T 12-10-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 VAPA_1c54640 20acba34452ac2db5e4a3ff12f060eea 442 PRINTS PR00447 Natural resistance-associated macrophage protein signature 350 367 2.5E-53 T 12-10-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 VAPA_1c54640 20acba34452ac2db5e4a3ff12f060eea 442 PRINTS PR00447 Natural resistance-associated macrophage protein signature 382 401 2.5E-53 T 12-10-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 VAPA_1c54640 20acba34452ac2db5e4a3ff12f060eea 442 PRINTS PR00447 Natural resistance-associated macrophage protein signature 322 341 2.5E-53 T 12-10-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 VAPA_1c54640 20acba34452ac2db5e4a3ff12f060eea 442 PRINTS PR00447 Natural resistance-associated macrophage protein signature 113 139 2.5E-53 T 12-10-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 VAPA_1c14960 e081dff9ddcf469c05c652b2681d2f66 321 SUPERFAMILY SSF54814 199 321 3.31E-37 T 12-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 VAPA_1c14960 e081dff9ddcf469c05c652b2681d2f66 321 Hamap MF_00367 GTPase Era [era]. 24 320 33.535 T 12-10-2018 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 VAPA_1c14960 e081dff9ddcf469c05c652b2681d2f66 321 SUPERFAMILY SSF52540 29 223 4.53E-40 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c14960 e081dff9ddcf469c05c652b2681d2f66 321 Pfam PF07650 KH domain 238 308 5.2E-17 T 12-10-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VAPA_1c14960 e081dff9ddcf469c05c652b2681d2f66 321 Gene3D G3DSA:3.30.300.20 203 321 8.7E-39 T 12-10-2018 IPR015946 K homology domain-like, alpha/beta VAPA_1c14960 e081dff9ddcf469c05c652b2681d2f66 321 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 28 188 3.6E-29 T 12-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 VAPA_1c14960 e081dff9ddcf469c05c652b2681d2f66 321 Gene3D G3DSA:3.40.50.300 23 201 3.7E-46 T 12-10-2018 VAPA_1c14960 e081dff9ddcf469c05c652b2681d2f66 321 Pfam PF01926 50S ribosome-binding GTPase 29 142 1.7E-23 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 VAPA_1c14960 e081dff9ddcf469c05c652b2681d2f66 321 TIGRFAM TIGR00436 era: GTP-binding protein Era 28 303 2.3E-80 T 12-10-2018 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 VAPA_1c14960 e081dff9ddcf469c05c652b2681d2f66 321 PRINTS PR00449 Transforming protein P21 ras signature 27 48 3.5E-6 T 12-10-2018 VAPA_1c14960 e081dff9ddcf469c05c652b2681d2f66 321 PRINTS PR00449 Transforming protein P21 ras signature 132 145 3.5E-6 T 12-10-2018 VAPA_1c14960 e081dff9ddcf469c05c652b2681d2f66 321 PRINTS PR00449 Transforming protein P21 ras signature 168 190 3.5E-6 T 12-10-2018 VAPA_2c00750 fac647bc23eb3e738f4514a9137d0f6b 388 Gene3D G3DSA:3.30.390.10 1 127 5.0E-69 T 12-10-2018 IPR029017 Enolase-like, N-terminal VAPA_2c00750 fac647bc23eb3e738f4514a9137d0f6b 388 SUPERFAMILY SSF51604 123 383 1.7E-55 T 12-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily VAPA_2c00750 fac647bc23eb3e738f4514a9137d0f6b 388 SUPERFAMILY SSF54826 1 139 1.37E-30 T 12-10-2018 VAPA_2c00750 fac647bc23eb3e738f4514a9137d0f6b 388 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 8 134 9.7E-5 T 12-10-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain VAPA_2c00750 fac647bc23eb3e738f4514a9137d0f6b 388 Pfam PF13378 Enolase C-terminal domain-like 165 376 7.9E-42 T 12-10-2018 IPR029065 Enolase C-terminal domain-like VAPA_2c00750 fac647bc23eb3e738f4514a9137d0f6b 388 Gene3D G3DSA:3.20.20.120 128 388 7.0E-67 T 12-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily VAPA_2c00750 fac647bc23eb3e738f4514a9137d0f6b 388 SMART SM00922 162 259 5.8E-14 T 12-10-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal VAPA_1c45680 1b68800775ade3c3b1134c4b8fe6ae1c 238 Gene3D G3DSA:3.40.50.2020 123 237 6.7E-15 T 12-10-2018 VAPA_1c45680 1b68800775ade3c3b1134c4b8fe6ae1c 238 Pfam PF00156 Phosphoribosyl transferase domain 175 232 2.2E-6 T 12-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 VAPA_1c45680 1b68800775ade3c3b1134c4b8fe6ae1c 238 SUPERFAMILY SSF53271 60 232 1.14E-22 T 12-10-2018 IPR029057 Phosphoribosyltransferase-like VAPA_1c05700 2e7e202cd341b0c2d4c0ba73f5fb0faf 325 SMART SM00342 232 315 3.5E-26 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 VAPA_1c05700 2e7e202cd341b0c2d4c0ba73f5fb0faf 325 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 269 311 - T 12-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 VAPA_1c05700 2e7e202cd341b0c2d4c0ba73f5fb0faf 325 Gene3D G3DSA:1.10.10.60 215 322 1.6E-26 T 12-10-2018 VAPA_1c05700 2e7e202cd341b0c2d4c0ba73f5fb0faf 325 SUPERFAMILY SSF46689 269 319 5.82E-10 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 VAPA_1c05700 2e7e202cd341b0c2d4c0ba73f5fb0faf 325 SUPERFAMILY SSF46689 216 266 1.12E-9 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 VAPA_1c05700 2e7e202cd341b0c2d4c0ba73f5fb0faf 325 Pfam PF12833 Helix-turn-helix domain 238 317 1.3E-21 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 VAPA_1c05700 2e7e202cd341b0c2d4c0ba73f5fb0faf 325 SUPERFAMILY SSF52317 8 197 6.52E-47 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like VAPA_1c05700 2e7e202cd341b0c2d4c0ba73f5fb0faf 325 Gene3D G3DSA:3.40.50.880 5 210 4.9E-55 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like VAPA_1c05700 2e7e202cd341b0c2d4c0ba73f5fb0faf 325 Pfam PF01965 DJ-1/PfpI family 8 175 5.8E-13 T 12-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 VAPA_1c47220 612c2299dfa1098487d8d080076b319a 71 SUPERFAMILY SSF46955 4 54 1.01E-16 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily VAPA_1c47220 612c2299dfa1098487d8d080076b319a 71 Pfam PF07825 Excisionase-like protein 4 52 2.5E-14 T 12-10-2018 IPR012884 Excisionase-like GO:0003677|GO:0006310 VAPA_1c47220 612c2299dfa1098487d8d080076b319a 71 Gene3D G3DSA:1.10.1660.20 3 70 9.5E-18 T 12-10-2018 IPR038137 Excisionase-like superfamily VAPA_1c16810 976042b3c5c9a64a6057801f84581db5 418 PIRSF PIRSF001235 6 417 2.1E-138 T 12-10-2018 IPR010158 Amidase, carbamoylase-type GO:0016813 VAPA_1c16810 976042b3c5c9a64a6057801f84581db5 418 Pfam PF07687 Peptidase dimerisation domain 217 318 1.9E-4 T 12-10-2018 IPR011650 Peptidase M20, dimerisation domain VAPA_1c16810 976042b3c5c9a64a6057801f84581db5 418 SUPERFAMILY SSF55031 217 332 2.62E-30 T 12-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain VAPA_1c16810 976042b3c5c9a64a6057801f84581db5 418 TIGRFAM TIGR01879 hydantase: amidase, hydantoinase/carbamoylase family 12 411 2.3E-131 T 12-10-2018 IPR010158 Amidase, carbamoylase-type GO:0016813 VAPA_1c16810 976042b3c5c9a64a6057801f84581db5 418 SUPERFAMILY SSF53187 5 412 1.37E-95 T 12-10-2018 VAPA_1c16810 976042b3c5c9a64a6057801f84581db5 418 Gene3D G3DSA:3.30.70.360 217 331 1.5E-151 T 12-10-2018 VAPA_1c16810 976042b3c5c9a64a6057801f84581db5 418 Pfam PF01546 Peptidase family M20/M25/M40 83 410 2.1E-35 T 12-10-2018 IPR002933 Peptidase M20 GO:0016787 VAPA_1c16810 976042b3c5c9a64a6057801f84581db5 418 Gene3D G3DSA:3.40.630.10 20 407 1.5E-151 T 12-10-2018 VAPA_1c36220 b85d04df6d4a1954ac37f6e67ee9291e 332 SMART SM00829 10 330 5.8E-49 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 VAPA_1c36220 b85d04df6d4a1954ac37f6e67ee9291e 332 TIGRFAM TIGR02824 quinone_pig3: putative NAD(P)H quinone oxidoreductase, PIG3 family 1 332 2.9E-142 T 12-10-2018 IPR014189 Quinone oxidoreductase PIG3 Reactome: R-HSA-6803205 VAPA_1c36220 b85d04df6d4a1954ac37f6e67ee9291e 332 Gene3D G3DSA:3.90.180.10 13 330 2.4E-104 T 12-10-2018 VAPA_1c36220 b85d04df6d4a1954ac37f6e67ee9291e 332 Pfam PF00107 Zinc-binding dehydrogenase 154 277 4.8E-34 T 12-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 VAPA_1c36220 b85d04df6d4a1954ac37f6e67ee9291e 332 SUPERFAMILY SSF51735 114 290 2.99E-56 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c36220 b85d04df6d4a1954ac37f6e67ee9291e 332 Gene3D G3DSA:3.40.50.720 123 265 2.4E-104 T 12-10-2018 VAPA_1c36220 b85d04df6d4a1954ac37f6e67ee9291e 332 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 91 1.2E-4 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 VAPA_1c36220 b85d04df6d4a1954ac37f6e67ee9291e 332 SUPERFAMILY SSF50129 1 143 1.12E-36 T 12-10-2018 IPR011032 GroES-like superfamily VAPA_1c08030 37d3ae45ae0ddaea01fb8824e2aff454 308 PIRSF PIRSF016184 1 308 9.6E-76 T 12-10-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 VAPA_1c08030 37d3ae45ae0ddaea01fb8824e2aff454 308 Pfam PF02567 Phenazine biosynthesis-like protein 9 304 6.0E-56 T 12-10-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 VAPA_1c08030 37d3ae45ae0ddaea01fb8824e2aff454 308 TIGRFAM TIGR00654 PhzF_family: phenazine biosynthesis protein, PhzF family 5 223 2.0E-48 T 12-10-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 VAPA_1c08030 37d3ae45ae0ddaea01fb8824e2aff454 308 Gene3D G3DSA:3.10.310.10 133 297 2.9E-24 T 12-10-2018 VAPA_1c08030 37d3ae45ae0ddaea01fb8824e2aff454 308 Gene3D G3DSA:3.10.310.10 2 132 2.8E-41 T 12-10-2018 VAPA_1c08030 37d3ae45ae0ddaea01fb8824e2aff454 308 SUPERFAMILY SSF54506 4 307 1.15E-73 T 12-10-2018 VAPA_1c33520 2db955dc43c95107ded068ff33f4dda2 484 SUPERFAMILY SSF103378 12 482 2.48E-160 T 12-10-2018 IPR036148 MmgE/PrpD superfamily GO:0016829 VAPA_1c33520 2db955dc43c95107ded068ff33f4dda2 484 Gene3D G3DSA:1.10.4100.10 26 462 4.4E-207 T 12-10-2018 VAPA_1c33520 2db955dc43c95107ded068ff33f4dda2 484 TIGRFAM TIGR02330 prpD: 2-methylcitrate dehydratase 13 483 6.7E-258 T 12-10-2018 IPR012705 2-methylcitrate dehydratase PrpD GO:0019629|GO:0047547|GO:0051537 KEGG: 00640+4.2.1.79 VAPA_1c33520 2db955dc43c95107ded068ff33f4dda2 484 Gene3D G3DSA:3.30.1330.120 286 427 4.4E-207 T 12-10-2018 VAPA_1c33520 2db955dc43c95107ded068ff33f4dda2 484 Pfam PF03972 MmgE/PrpD family 27 465 3.1E-161 T 12-10-2018 IPR005656 MmgE/PrpD GO:0016829 VAPA_1c24210 a3dbbdbaf1659c7c7855f987a198e040 252 SUPERFAMILY SSF161098 55 236 3.27E-24 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c24210 a3dbbdbaf1659c7c7855f987a198e040 252 Gene3D G3DSA:1.10.3720.10 52 248 1.3E-18 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c24210 a3dbbdbaf1659c7c7855f987a198e040 252 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 75 247 5.3E-21 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 VAPA_1c26070 d35bed8f621d8c710243b4e54f55e1ef 332 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 95 322 6.3E-16 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 VAPA_1c26070 d35bed8f621d8c710243b4e54f55e1ef 332 SUPERFAMILY SSF161098 73 312 1.57E-38 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c26070 d35bed8f621d8c710243b4e54f55e1ef 332 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 73 141 4.9E-13 T 12-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 VAPA_2c02620 f494f4869c2ce26fbd66b73dfe5a5c11 430 Pfam PF01266 FAD dependent oxidoreductase 26 387 2.4E-61 T 12-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 VAPA_2c02620 f494f4869c2ce26fbd66b73dfe5a5c11 430 Gene3D G3DSA:3.50.50.60 26 388 5.8E-77 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_2c02620 f494f4869c2ce26fbd66b73dfe5a5c11 430 SUPERFAMILY SSF51905 25 404 4.14E-46 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_2c02620 f494f4869c2ce26fbd66b73dfe5a5c11 430 Gene3D G3DSA:3.30.9.10 120 351 5.8E-77 T 12-10-2018 VAPA_1c07730 af1bc1d98c1720877dbbcce7d999f3a4 641 SMART SM00388 275 341 2.9E-15 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 VAPA_1c07730 af1bc1d98c1720877dbbcce7d999f3a4 641 Pfam PF13426 PAS domain 159 262 2.7E-13 T 12-10-2018 IPR000014 PAS domain VAPA_1c07730 af1bc1d98c1720877dbbcce7d999f3a4 641 Pfam PF13426 PAS domain 32 134 3.4E-12 T 12-10-2018 IPR000014 PAS domain VAPA_1c07730 af1bc1d98c1720877dbbcce7d999f3a4 641 SUPERFAMILY SSF55785 133 261 2.09E-24 T 12-10-2018 IPR035965 PAS domain superfamily VAPA_1c07730 af1bc1d98c1720877dbbcce7d999f3a4 641 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 387 500 1.9E-25 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase VAPA_1c07730 af1bc1d98c1720877dbbcce7d999f3a4 641 SMART SM00086 221 263 0.22 T 12-10-2018 IPR001610 PAC motif VAPA_1c07730 af1bc1d98c1720877dbbcce7d999f3a4 641 SMART SM00086 93 135 20.0 T 12-10-2018 IPR001610 PAC motif VAPA_1c07730 af1bc1d98c1720877dbbcce7d999f3a4 641 SMART SM00448 517 629 1.8E-31 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_1c07730 af1bc1d98c1720877dbbcce7d999f3a4 641 SUPERFAMILY SSF52172 517 635 1.99E-34 T 12-10-2018 IPR011006 CheY-like superfamily VAPA_1c07730 af1bc1d98c1720877dbbcce7d999f3a4 641 SUPERFAMILY SSF47384 264 342 6.08E-15 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 VAPA_1c07730 af1bc1d98c1720877dbbcce7d999f3a4 641 SUPERFAMILY SSF55874 330 500 5.24E-42 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_1c07730 af1bc1d98c1720877dbbcce7d999f3a4 641 Gene3D G3DSA:3.30.450.20 148 264 3.0E-22 T 12-10-2018 VAPA_1c07730 af1bc1d98c1720877dbbcce7d999f3a4 641 SUPERFAMILY SSF55785 21 127 9.22E-21 T 12-10-2018 IPR035965 PAS domain superfamily VAPA_1c07730 af1bc1d98c1720877dbbcce7d999f3a4 641 SMART SM00387 387 501 8.1E-34 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase VAPA_1c07730 af1bc1d98c1720877dbbcce7d999f3a4 641 Gene3D G3DSA:1.10.287.130 265 341 2.7E-15 T 12-10-2018 VAPA_1c07730 af1bc1d98c1720877dbbcce7d999f3a4 641 PRINTS PR00344 Bacterial sensor protein C-terminal signature 485 498 3.7E-14 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c07730 af1bc1d98c1720877dbbcce7d999f3a4 641 PRINTS PR00344 Bacterial sensor protein C-terminal signature 442 452 3.7E-14 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c07730 af1bc1d98c1720877dbbcce7d999f3a4 641 PRINTS PR00344 Bacterial sensor protein C-terminal signature 459 477 3.7E-14 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c07730 af1bc1d98c1720877dbbcce7d999f3a4 641 PRINTS PR00344 Bacterial sensor protein C-terminal signature 424 438 3.7E-14 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c07730 af1bc1d98c1720877dbbcce7d999f3a4 641 Gene3D G3DSA:3.40.50.12740 516 640 2.3E-33 T 12-10-2018 VAPA_1c07730 af1bc1d98c1720877dbbcce7d999f3a4 641 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 144 266 1.0E-18 T 12-10-2018 IPR000014 PAS domain VAPA_1c07730 af1bc1d98c1720877dbbcce7d999f3a4 641 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 21 142 1.1E-18 T 12-10-2018 IPR000014 PAS domain VAPA_1c07730 af1bc1d98c1720877dbbcce7d999f3a4 641 Gene3D G3DSA:3.30.565.10 342 503 4.5E-41 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_1c07730 af1bc1d98c1720877dbbcce7d999f3a4 641 SMART SM00091 19 86 9.4E-6 T 12-10-2018 IPR000014 PAS domain VAPA_1c07730 af1bc1d98c1720877dbbcce7d999f3a4 641 SMART SM00091 147 216 0.0073 T 12-10-2018 IPR000014 PAS domain VAPA_1c07730 af1bc1d98c1720877dbbcce7d999f3a4 641 Pfam PF00072 Response regulator receiver domain 519 629 4.9E-21 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_1c07730 af1bc1d98c1720877dbbcce7d999f3a4 641 Pfam PF00512 His Kinase A (phospho-acceptor) domain 277 341 1.6E-13 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 VAPA_1c07730 af1bc1d98c1720877dbbcce7d999f3a4 641 Gene3D G3DSA:3.30.450.20 18 147 2.1E-24 T 12-10-2018 VAPA_1c03390 15ee1d398913ad4704286c5919f9509e 301 Gene3D G3DSA:1.10.10.10 3 92 2.1E-23 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c03390 15ee1d398913ad4704286c5919f9509e 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 1.2E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c03390 15ee1d398913ad4704286c5919f9509e 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 1.2E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c03390 15ee1d398913ad4704286c5919f9509e 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 1.2E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c03390 15ee1d398913ad4704286c5919f9509e 301 SUPERFAMILY SSF53850 92 298 2.79E-29 T 12-10-2018 VAPA_1c03390 15ee1d398913ad4704286c5919f9509e 301 Pfam PF03466 LysR substrate binding domain 90 295 1.1E-30 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_1c03390 15ee1d398913ad4704286c5919f9509e 301 SUPERFAMILY SSF46785 3 112 4.45E-24 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c03390 15ee1d398913ad4704286c5919f9509e 301 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 64 4.8E-20 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c03390 15ee1d398913ad4704286c5919f9509e 301 Gene3D G3DSA:3.40.190.290 93 298 3.1E-26 T 12-10-2018 VAPA_1c41270 eb52ab936acbfd58a420a3d30a2c74e3 400 PIRSF PIRSF001434 1 398 1.4E-124 T 12-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 VAPA_1c41270 eb52ab936acbfd58a420a3d30a2c74e3 400 SUPERFAMILY SSF53383 34 395 1.13E-89 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase VAPA_1c41270 eb52ab936acbfd58a420a3d30a2c74e3 400 Gene3D G3DSA:3.90.1150.10 265 397 2.7E-39 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 VAPA_1c41270 eb52ab936acbfd58a420a3d30a2c74e3 400 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 208 222 - T 12-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 VAPA_1c41270 eb52ab936acbfd58a420a3d30a2c74e3 400 TIGRFAM TIGR01324 cysta_beta_ly_B: cystathionine beta-lyase 15 397 4.2E-122 T 12-10-2018 IPR006233 Cystathionine beta-lyase, bacterial GO:0004121|GO:0005737|GO:0006520 KEGG: 00270+4.4.1.8|KEGG: 00450+4.4.1.8 VAPA_1c41270 eb52ab936acbfd58a420a3d30a2c74e3 400 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 14 394 1.1E-99 T 12-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 VAPA_1c41270 eb52ab936acbfd58a420a3d30a2c74e3 400 Gene3D G3DSA:3.40.640.10 9 264 5.3E-69 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 VAPA_1c43540 fec75c238b8476344700476749300b0c 228 Pfam PF13861 FlgD Tudor-like domain 85 225 6.8E-14 T 12-10-2018 IPR025963 FlgD Tudor-like domain VAPA_1c43540 fec75c238b8476344700476749300b0c 228 Gene3D G3DSA:2.30.30.910 86 222 1.3E-29 T 12-10-2018 VAPA_1c43540 fec75c238b8476344700476749300b0c 228 Pfam PF13860 FlgD Ig-like domain 118 185 8.8E-22 T 12-10-2018 IPR025965 FlgD Ig-like domain VAPA_1c43540 fec75c238b8476344700476749300b0c 228 Pfam PF03963 Flagellar hook capping protein - N-terminal region 10 75 4.6E-22 T 12-10-2018 IPR005648 Flagellar hook capping protein VAPA_1c43540 fec75c238b8476344700476749300b0c 228 Gene3D G3DSA:2.60.40.4070 102 194 1.3E-29 T 12-10-2018 VAPA_1c10100 4d370b7720448c71b39b52ff2fbf3994 517 SUPERFAMILY SSF46689 371 501 4.93E-10 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 VAPA_1c10100 4d370b7720448c71b39b52ff2fbf3994 517 SMART SM00448 5 116 1.1E-35 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_1c10100 4d370b7720448c71b39b52ff2fbf3994 517 Gene3D G3DSA:1.10.10.60 441 503 1.2E-11 T 12-10-2018 VAPA_1c10100 4d370b7720448c71b39b52ff2fbf3994 517 Pfam PF00072 Response regulator receiver domain 7 116 1.0E-26 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_1c10100 4d370b7720448c71b39b52ff2fbf3994 517 Pfam PF02954 Bacterial regulatory protein, Fis family 459 498 1.6E-10 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 VAPA_1c10100 4d370b7720448c71b39b52ff2fbf3994 517 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 482 502 6.4E-8 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 VAPA_1c10100 4d370b7720448c71b39b52ff2fbf3994 517 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 465 482 6.4E-8 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 VAPA_1c10100 4d370b7720448c71b39b52ff2fbf3994 517 Gene3D G3DSA:1.10.8.60 329 400 1.0E-16 T 12-10-2018 VAPA_1c10100 4d370b7720448c71b39b52ff2fbf3994 517 Gene3D G3DSA:3.40.50.300 149 328 2.1E-59 T 12-10-2018 VAPA_1c10100 4d370b7720448c71b39b52ff2fbf3994 517 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 181 194 - T 12-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 VAPA_1c10100 4d370b7720448c71b39b52ff2fbf3994 517 Gene3D G3DSA:3.40.50.2300 1 134 1.9E-34 T 12-10-2018 VAPA_1c10100 4d370b7720448c71b39b52ff2fbf3994 517 Pfam PF00158 Sigma-54 interaction domain 157 323 7.9E-66 T 12-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 VAPA_1c10100 4d370b7720448c71b39b52ff2fbf3994 517 SMART SM00382 177 320 9.4E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c10100 4d370b7720448c71b39b52ff2fbf3994 517 SUPERFAMILY SSF52172 4 201 2.7E-40 T 12-10-2018 IPR011006 CheY-like superfamily VAPA_1c10100 4d370b7720448c71b39b52ff2fbf3994 517 SUPERFAMILY SSF52540 157 396 9.91E-65 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c10640 d3f288c8d456f24e1215e7efb9320d82 228 Gene3D G3DSA:1.20.120.520 1 158 7.7E-11 T 12-10-2018 VAPA_1c10640 d3f288c8d456f24e1215e7efb9320d82 228 Pfam PF01814 Hemerythrin HHE cation binding domain 6 133 6.1E-6 T 12-10-2018 IPR012312 Haemerythrin-like Reactome: R-HSA-390471|Reactome: R-HSA-8951664|Reactome: R-HSA-917937|Reactome: R-HSA-983168 VAPA_1c37640 f4bf5cbf0b873044dfb97ac82b414c54 265 Gene3D G3DSA:3.90.226.10 1 208 4.5E-54 T 12-10-2018 VAPA_1c37640 f4bf5cbf0b873044dfb97ac82b414c54 265 Gene3D G3DSA:1.10.12.10 209 265 2.1E-28 T 12-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal VAPA_1c37640 f4bf5cbf0b873044dfb97ac82b414c54 265 SUPERFAMILY SSF52096 31 264 4.83E-58 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily VAPA_1c37640 f4bf5cbf0b873044dfb97ac82b414c54 265 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 109 129 - T 12-10-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824 VAPA_1c37640 f4bf5cbf0b873044dfb97ac82b414c54 265 Pfam PF00378 Enoyl-CoA hydratase/isomerase 41 264 6.4E-36 T 12-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 VAPA_1c43700 f3e4e3bb368d4e9fe868778857afb02d 223 PRINTS PR00502 NUDIX hydrolase family signature 47 62 1.8E-7 T 12-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 VAPA_1c43700 f3e4e3bb368d4e9fe868778857afb02d 223 PRINTS PR00502 NUDIX hydrolase family signature 33 47 1.8E-7 T 12-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 VAPA_1c43700 f3e4e3bb368d4e9fe868778857afb02d 223 ProSitePatterns PS00893 Nudix box signature. 38 59 - T 12-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 VAPA_1c43700 f3e4e3bb368d4e9fe868778857afb02d 223 Hamap MF_00298 RNA pyrophosphohydrolase [rppH]. 1 156 37.431 T 12-10-2018 IPR022927 RNA pyrophosphohydrolase RppH VAPA_1c43700 f3e4e3bb368d4e9fe868778857afb02d 223 Gene3D G3DSA:3.90.79.10 1 157 4.8E-43 T 12-10-2018 VAPA_1c43700 f3e4e3bb368d4e9fe868778857afb02d 223 Pfam PF00293 NUDIX domain 7 134 2.5E-23 T 12-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 VAPA_1c43700 f3e4e3bb368d4e9fe868778857afb02d 223 SUPERFAMILY SSF55811 6 162 6.5E-31 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 VAPA_1c04400 96f875a6f6231c51ec1b65ba1f7976c3 243 ProSitePatterns PS00211 ABC transporters family signature. 144 158 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_1c04400 96f875a6f6231c51ec1b65ba1f7976c3 243 Pfam PF00005 ABC transporter 29 171 5.2E-29 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c04400 96f875a6f6231c51ec1b65ba1f7976c3 243 SMART SM00382 36 220 5.6E-10 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c04400 96f875a6f6231c51ec1b65ba1f7976c3 243 SUPERFAMILY SSF52540 11 236 1.17E-52 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c04400 96f875a6f6231c51ec1b65ba1f7976c3 243 Gene3D G3DSA:3.40.50.300 7 243 3.5E-56 T 12-10-2018 VAPA_1c02300 49881b5916e018d159469ceecf66fe33 160 SUPERFAMILY SSF141452 2 158 1.44E-43 T 12-10-2018 IPR036624 Hcp1-like superfamily VAPA_1c02300 49881b5916e018d159469ceecf66fe33 160 Gene3D G3DSA:2.30.110.20 1 160 7.5E-53 T 12-10-2018 IPR036624 Hcp1-like superfamily VAPA_1c02300 49881b5916e018d159469ceecf66fe33 160 Pfam PF05638 Type VI secretion system effector, Hcp 6 135 5.7E-34 T 12-10-2018 IPR008514 Type VI secretion system effector, Hcp VAPA_2c03160 49881b5916e018d159469ceecf66fe33 160 SUPERFAMILY SSF141452 2 158 1.44E-43 T 12-10-2018 IPR036624 Hcp1-like superfamily VAPA_2c03160 49881b5916e018d159469ceecf66fe33 160 Gene3D G3DSA:2.30.110.20 1 160 7.5E-53 T 12-10-2018 IPR036624 Hcp1-like superfamily VAPA_2c03160 49881b5916e018d159469ceecf66fe33 160 Pfam PF05638 Type VI secretion system effector, Hcp 6 135 5.7E-34 T 12-10-2018 IPR008514 Type VI secretion system effector, Hcp VAPA_1c26430 8746ad4c35e453491ee6292fe97dd67c 343 Gene3D G3DSA:3.20.20.100 1 343 2.3E-143 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily VAPA_1c26430 8746ad4c35e453491ee6292fe97dd67c 343 SUPERFAMILY SSF51430 1 318 1.96E-97 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily VAPA_1c26430 8746ad4c35e453491ee6292fe97dd67c 343 Pfam PF00248 Aldo/keto reductase family 16 318 6.6E-68 T 12-10-2018 IPR023210 NADP-dependent oxidoreductase domain VAPA_1c26430 8746ad4c35e453491ee6292fe97dd67c 343 PRINTS PR00069 Aldo-keto reductase signature 143 160 1.3E-7 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 VAPA_1c26430 8746ad4c35e453491ee6292fe97dd67c 343 PRINTS PR00069 Aldo-keto reductase signature 48 72 1.3E-7 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 VAPA_1c26430 8746ad4c35e453491ee6292fe97dd67c 343 PRINTS PR00069 Aldo-keto reductase signature 112 130 1.3E-7 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 VAPA_1c34140 55b906f593c1d49a709c61f917812c0f 352 SUPERFAMILY SSF51412 2 346 3.66E-65 T 12-10-2018 VAPA_1c34140 55b906f593c1d49a709c61f917812c0f 352 Gene3D G3DSA:3.20.20.70 2 351 1.6E-115 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 VAPA_1c34140 55b906f593c1d49a709c61f917812c0f 352 Pfam PF03060 Nitronate monooxygenase 5 344 9.3E-76 T 12-10-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 VAPA_2c05450 046e8582c4da3af3f4033b2e640a268f 667 Pfam PF00361 Proton-conducting membrane transporter 129 421 4.7E-54 T 12-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VAPA_2c05450 046e8582c4da3af3f4033b2e640a268f 667 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 237 261 8.7E-10 T 12-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VAPA_2c05450 046e8582c4da3af3f4033b2e640a268f 667 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 166 190 8.7E-10 T 12-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VAPA_2c05450 046e8582c4da3af3f4033b2e640a268f 667 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 387 413 8.7E-10 T 12-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VAPA_1c20980 4d0d147fd53461f42c7d64d3955d79e3 260 SUPERFAMILY SSF56219 1 257 7.07E-79 T 12-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily VAPA_1c20980 4d0d147fd53461f42c7d64d3955d79e3 260 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 4 248 3.8E-19 T 12-10-2018 IPR005135 Endonuclease/exonuclease/phosphatase VAPA_1c20980 4d0d147fd53461f42c7d64d3955d79e3 260 TIGRFAM TIGR00195 exoDNase_III: exodeoxyribonuclease III 1 255 4.6E-68 T 12-10-2018 VAPA_1c20980 4d0d147fd53461f42c7d64d3955d79e3 260 Gene3D G3DSA:3.60.10.10 1 257 3.0E-71 T 12-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily VAPA_1c20980 4d0d147fd53461f42c7d64d3955d79e3 260 TIGRFAM TIGR00633 xth: exodeoxyribonuclease III (xth) 1 256 6.5E-70 T 12-10-2018 IPR004808 AP endonuclease 1 GO:0004518|GO:0006281 VAPA_1c20770 2964b2d8bf78bf4342d3a03810551d13 454 Pfam PF17042 Putative nucleotide-binding of sugar-metabolising enzyme 283 440 3.7E-29 T 12-10-2018 IPR031475 Four-carbon acid sugar kinase, C-terminal domain VAPA_1c20770 2964b2d8bf78bf4342d3a03810551d13 454 SUPERFAMILY SSF142764 9 444 2.35E-80 T 12-10-2018 VAPA_1c20770 2964b2d8bf78bf4342d3a03810551d13 454 Pfam PF07005 Putative sugar-binding N-terminal domain 9 258 5.6E-51 T 12-10-2018 IPR010737 Four-carbon acid sugar kinase, N-terminal domain VAPA_1c20770 2964b2d8bf78bf4342d3a03810551d13 454 Gene3D G3DSA:3.40.50.10840 6 267 5.9E-62 T 12-10-2018 IPR037051 Four-carbon acid sugar kinase, N-terminal domain superfamily VAPA_1c20770 2964b2d8bf78bf4342d3a03810551d13 454 Gene3D G3DSA:3.40.980.20 270 448 2.6E-32 T 12-10-2018 VAPA_1c49470 0083a98e2793f8765d32433d36d51f61 593 Pfam PF01494 FAD binding domain 64 404 7.2E-60 T 12-10-2018 IPR002938 FAD-binding domain GO:0071949 VAPA_1c49470 0083a98e2793f8765d32433d36d51f61 593 Gene3D G3DSA:3.50.50.60 65 404 9.1E-88 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c49470 0083a98e2793f8765d32433d36d51f61 593 Gene3D G3DSA:3.40.30.120 450 590 5.1E-10 T 12-10-2018 VAPA_1c49470 0083a98e2793f8765d32433d36d51f61 593 Gene3D G3DSA:3.30.70.2450 246 335 9.1E-88 T 12-10-2018 VAPA_1c49470 0083a98e2793f8765d32433d36d51f61 593 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 217 232 7.3E-27 T 12-10-2018 VAPA_1c49470 0083a98e2793f8765d32433d36d51f61 593 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 379 397 7.3E-27 T 12-10-2018 VAPA_1c49470 0083a98e2793f8765d32433d36d51f61 593 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 64 86 7.3E-27 T 12-10-2018 VAPA_1c49470 0083a98e2793f8765d32433d36d51f61 593 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 346 361 7.3E-27 T 12-10-2018 VAPA_1c49470 0083a98e2793f8765d32433d36d51f61 593 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 361 377 7.3E-27 T 12-10-2018 VAPA_1c49470 0083a98e2793f8765d32433d36d51f61 593 SUPERFAMILY SSF51905 64 439 6.29E-57 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c15680 94af3f6f5f08c32a5af2ca614c32332a 127 ProSitePatterns PS01015 Ribosomal protein L19 signature. 88 103 - T 12-10-2018 IPR018257 Ribosomal protein L19, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 VAPA_1c15680 94af3f6f5f08c32a5af2ca614c32332a 127 SUPERFAMILY SSF50104 1 117 2.91E-44 T 12-10-2018 IPR008991 Translation protein SH3-like domain superfamily VAPA_1c15680 94af3f6f5f08c32a5af2ca614c32332a 127 Gene3D G3DSA:2.30.30.790 6 119 9.3E-15 T 12-10-2018 IPR038657 Ribosomal protein L19 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 VAPA_1c15680 94af3f6f5f08c32a5af2ca614c32332a 127 Pfam PF01245 Ribosomal protein L19 3 115 9.7E-46 T 12-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 VAPA_1c15680 94af3f6f5f08c32a5af2ca614c32332a 127 PIRSF PIRSF002191 1 127 3.2E-50 T 12-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 VAPA_1c15680 94af3f6f5f08c32a5af2ca614c32332a 127 Hamap MF_00402 50S ribosomal protein L19 [rplS]. 1 116 30.051 T 12-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 VAPA_1c15680 94af3f6f5f08c32a5af2ca614c32332a 127 TIGRFAM TIGR01024 rplS_bact: ribosomal protein bL19 1 115 7.7E-48 T 12-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 VAPA_1c15680 94af3f6f5f08c32a5af2ca614c32332a 127 ProSitePatterns PS00823 Dehydrins signature 2. 111 118 - T 12-10-2018 IPR030513 Dehydrin, conserved site VAPA_1c15680 94af3f6f5f08c32a5af2ca614c32332a 127 PRINTS PR00061 Ribosomal protein L19 signature 90 115 5.2E-36 T 12-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 VAPA_1c15680 94af3f6f5f08c32a5af2ca614c32332a 127 PRINTS PR00061 Ribosomal protein L19 signature 6 35 5.2E-36 T 12-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 VAPA_1c15680 94af3f6f5f08c32a5af2ca614c32332a 127 PRINTS PR00061 Ribosomal protein L19 signature 36 65 5.2E-36 T 12-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 VAPA_1c30270 a0df384e309de1827a7ad25f85c28f3d 665 Gene3D G3DSA:3.30.300.30 536 665 2.0E-27 T 12-10-2018 VAPA_1c30270 a0df384e309de1827a7ad25f85c28f3d 665 TIGRFAM TIGR02188 Ac_CoA_lig_AcsA: acetate--CoA ligase 32 663 8.9E-283 T 12-10-2018 IPR011904 Acetate-CoA ligase GO:0003987|GO:0016208|GO:0019427 KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857|Reactome: R-HSA-71384 VAPA_1c30270 a0df384e309de1827a7ad25f85c28f3d 665 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 36 91 3.2E-17 T 12-10-2018 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857 VAPA_1c30270 a0df384e309de1827a7ad25f85c28f3d 665 Pfam PF00501 AMP-binding enzyme 102 539 3.6E-91 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 VAPA_1c30270 a0df384e309de1827a7ad25f85c28f3d 665 Pfam PF13193 AMP-binding enzyme C-terminal domain 548 630 6.1E-25 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain VAPA_1c30270 a0df384e309de1827a7ad25f85c28f3d 665 ProSitePatterns PS00455 Putative AMP-binding domain signature. 271 282 - T 12-10-2018 IPR020845 AMP-binding, conserved site VAPA_1c30270 a0df384e309de1827a7ad25f85c28f3d 665 Hamap MF_01123 Acetyl-coenzyme A synthetase [acs]. 13 665 48.959 T 12-10-2018 IPR011904 Acetate-CoA ligase GO:0003987|GO:0016208|GO:0019427 KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857|Reactome: R-HSA-71384 VAPA_1c30270 a0df384e309de1827a7ad25f85c28f3d 665 SUPERFAMILY SSF56801 28 661 1.44E-164 T 12-10-2018 VAPA_1c30270 a0df384e309de1827a7ad25f85c28f3d 665 Gene3D G3DSA:3.40.50.12780 82 535 1.8E-99 T 12-10-2018 VAPA_1c54710 e515b2a21df7d0fa41bb46ca3b9b99df 246 Pfam PF00483 Nucleotidyl transferase 10 243 2.3E-15 T 12-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 VAPA_1c54710 e515b2a21df7d0fa41bb46ca3b9b99df 246 Gene3D G3DSA:3.90.550.10 8 245 1.5E-39 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases VAPA_1c54710 e515b2a21df7d0fa41bb46ca3b9b99df 246 SUPERFAMILY SSF53448 9 244 5.41E-42 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases VAPA_1c53920 a2a8effbc985eb6a983a9282740bafa7 573 Pfam PF15864 Protein glycosylation ligase 167 190 6.2E-9 T 12-10-2018 IPR031726 Protein glycosylation ligase domain VAPA_1c53920 a2a8effbc985eb6a983a9282740bafa7 573 Pfam PF04932 O-Antigen ligase 205 350 1.5E-11 T 12-10-2018 IPR007016 O-antigen ligase-related VAPA_1c53920 a2a8effbc985eb6a983a9282740bafa7 573 Pfam PF11846 Virulence factor membrane-bound polymerase, C-terminal 374 539 5.4E-15 T 12-10-2018 IPR021797 Virulence factor membrane-bound polymerase, C-terminal VAPA_1c30750 94864f6b17bd1deb02459a48a7ddd3d2 319 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 46 317 3.7E-34 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c30750 94864f6b17bd1deb02459a48a7ddd3d2 319 Gene3D G3DSA:3.40.190.150 28 311 5.6E-75 T 12-10-2018 VAPA_1c30750 94864f6b17bd1deb02459a48a7ddd3d2 319 SUPERFAMILY SSF53850 31 227 2.9E-7 T 12-10-2018 VAPA_1c30750 94864f6b17bd1deb02459a48a7ddd3d2 319 Gene3D G3DSA:3.40.190.10 122 246 5.6E-75 T 12-10-2018 VAPA_1c30750 94864f6b17bd1deb02459a48a7ddd3d2 319 PIRSF PIRSF017082 1 319 3.7E-103 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c46080 458599197a44e7508ea8727ef6d54983 324 PIRSF PIRSF017082 2 323 5.7E-74 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c46080 458599197a44e7508ea8727ef6d54983 324 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 45 319 6.9E-75 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c46080 458599197a44e7508ea8727ef6d54983 324 Gene3D G3DSA:3.40.190.150 27 313 8.0E-103 T 12-10-2018 VAPA_1c46080 458599197a44e7508ea8727ef6d54983 324 SUPERFAMILY SSF53850 108 282 5.77E-13 T 12-10-2018 VAPA_1c46080 458599197a44e7508ea8727ef6d54983 324 Gene3D G3DSA:3.40.190.10 123 249 8.0E-103 T 12-10-2018 VAPA_1c24760 b4029ddfc950eec5f219afce8caf8856 535 Gene3D G3DSA:1.10.530.10 98 267 2.4E-31 T 12-10-2018 VAPA_1c24760 b4029ddfc950eec5f219afce8caf8856 535 Pfam PF01476 LysM domain 359 393 0.015 T 12-10-2018 IPR018392 LysM domain VAPA_1c24760 b4029ddfc950eec5f219afce8caf8856 535 Pfam PF01476 LysM domain 430 454 0.11 T 12-10-2018 IPR018392 LysM domain VAPA_1c24760 b4029ddfc950eec5f219afce8caf8856 535 Gene3D G3DSA:3.10.350.10 419 463 2.5E-5 T 12-10-2018 IPR036779 LysM domain superfamily VAPA_1c24760 b4029ddfc950eec5f219afce8caf8856 535 SUPERFAMILY SSF53955 118 277 3.09E-41 T 12-10-2018 IPR023346 Lysozyme-like domain superfamily VAPA_1c24760 b4029ddfc950eec5f219afce8caf8856 535 Gene3D G3DSA:3.10.350.10 352 418 2.5E-5 T 12-10-2018 IPR036779 LysM domain superfamily VAPA_1c24760 b4029ddfc950eec5f219afce8caf8856 535 ProSitePatterns PS00922 Prokaryotic transglycosylases signature. 139 167 - T 12-10-2018 IPR000189 Prokaryotic transglycosylase, active site GO:0000270|GO:0008933|GO:0016020 VAPA_1c24760 b4029ddfc950eec5f219afce8caf8856 535 Pfam PF01464 Transglycosylase SLT domain 126 228 1.6E-25 T 12-10-2018 IPR008258 Transglycosylase SLT domain 1 VAPA_1c39740 cfe0dd18b40bf84ca8e6baa3e6dd9da5 436 Pfam PF03471 Transporter associated domain 349 425 2.7E-19 T 12-10-2018 IPR005170 Transporter-associated domain VAPA_1c39740 cfe0dd18b40bf84ca8e6baa3e6dd9da5 436 SMART SM01091 348 430 9.1E-27 T 12-10-2018 IPR005170 Transporter-associated domain VAPA_1c39740 cfe0dd18b40bf84ca8e6baa3e6dd9da5 436 Gene3D G3DSA:3.10.580.10 192 345 2.9E-37 T 12-10-2018 VAPA_1c39740 cfe0dd18b40bf84ca8e6baa3e6dd9da5 436 Pfam PF01595 Domain of unknown function DUF21 5 196 9.7E-42 T 12-10-2018 IPR002550 CNNM, transmembrane domain VAPA_1c39740 cfe0dd18b40bf84ca8e6baa3e6dd9da5 436 Pfam PF00571 CBS domain 286 333 3.3E-5 T 12-10-2018 IPR000644 CBS domain VAPA_1c39740 cfe0dd18b40bf84ca8e6baa3e6dd9da5 436 Pfam PF00571 CBS domain 217 271 0.0013 T 12-10-2018 IPR000644 CBS domain VAPA_1c39740 cfe0dd18b40bf84ca8e6baa3e6dd9da5 436 Gene3D G3DSA:3.30.465.10 346 428 9.8E-26 T 12-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 VAPA_1c39740 cfe0dd18b40bf84ca8e6baa3e6dd9da5 436 SUPERFAMILY SSF54631 198 337 6.32E-24 T 12-10-2018 VAPA_1c39740 cfe0dd18b40bf84ca8e6baa3e6dd9da5 436 SUPERFAMILY SSF56176 347 432 2.13E-19 T 12-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 VAPA_2c02460 7fda250f3121ca5a7ef9c5dc4c5d459a 437 SUPERFAMILY SSF53383 70 415 1.45E-79 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase VAPA_2c02460 7fda250f3121ca5a7ef9c5dc4c5d459a 437 SUPERFAMILY SSF46785 3 44 3.08E-5 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_2c02460 7fda250f3121ca5a7ef9c5dc4c5d459a 437 Gene3D G3DSA:3.40.640.10 74 425 9.3E-113 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 VAPA_2c02460 7fda250f3121ca5a7ef9c5dc4c5d459a 437 Pfam PF00155 Aminotransferase class I and II 103 375 7.0E-24 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 VAPA_2c02460 7fda250f3121ca5a7ef9c5dc4c5d459a 437 Gene3D G3DSA:1.10.10.10 1 73 5.2E-8 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c53890 60df57ea3811207bdcfda81ddf2f6829 315 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 154 231 2.0E-14 T 12-10-2018 IPR004104 Oxidoreductase, C-terminal GO:0016491|GO:0055114 VAPA_1c53890 60df57ea3811207bdcfda81ddf2f6829 315 Gene3D G3DSA:3.40.50.720 2 132 2.0E-28 T 12-10-2018 VAPA_1c53890 60df57ea3811207bdcfda81ddf2f6829 315 SUPERFAMILY SSF55347 166 233 1.2E-5 T 12-10-2018 VAPA_1c53890 60df57ea3811207bdcfda81ddf2f6829 315 SUPERFAMILY SSF51735 4 143 1.2E-23 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c53890 60df57ea3811207bdcfda81ddf2f6829 315 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 4 127 2.6E-18 T 12-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 VAPA_1c53890 60df57ea3811207bdcfda81ddf2f6829 315 Gene3D G3DSA:3.30.360.10 133 315 3.9E-63 T 12-10-2018 VAPA_1c21540 82b082e9d78595d90844b65914b3d5f4 565 SUPERFAMILY SSF51735 429 558 4.09E-28 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c21540 82b082e9d78595d90844b65914b3d5f4 565 Pfam PF00999 Sodium/hydrogen exchanger family 13 387 1.7E-73 T 12-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 VAPA_1c21540 82b082e9d78595d90844b65914b3d5f4 565 Gene3D G3DSA:3.40.50.720 425 563 3.7E-30 T 12-10-2018 VAPA_1c21540 82b082e9d78595d90844b65914b3d5f4 565 Pfam PF02254 TrkA-N domain 430 542 1.4E-23 T 12-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 VAPA_1c21540 82b082e9d78595d90844b65914b3d5f4 565 Gene3D G3DSA:1.20.1530.20 5 396 1.4E-78 T 12-10-2018 IPR038770 Sodium/solute symporter superfamily VAPA_1c48560 3295d79debf6717bd30b8a4f3f2df06f 1917 Gene3D G3DSA:3.30.190.20 1135 1256 3.5E-27 T 12-10-2018 VAPA_1c48560 3295d79debf6717bd30b8a4f3f2df06f 1917 TIGRFAM TIGR00630 uvra: excinuclease ABC subunit A 6 966 7.8E-285 T 12-10-2018 IPR004602 UvrABC system subunit A GO:0003677|GO:0006289|GO:0009380|GO:0016887 VAPA_1c48560 3295d79debf6717bd30b8a4f3f2df06f 1917 SMART SM00382 660 948 0.9 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c48560 3295d79debf6717bd30b8a4f3f2df06f 1917 SMART SM00382 1587 1882 1.2 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c48560 3295d79debf6717bd30b8a4f3f2df06f 1917 SMART SM00382 25 593 20.0 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c48560 3295d79debf6717bd30b8a4f3f2df06f 1917 SMART SM00382 1032 1512 3.0 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c48560 3295d79debf6717bd30b8a4f3f2df06f 1917 ProSitePatterns PS00211 ABC transporters family signature. 1435 1449 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_1c48560 3295d79debf6717bd30b8a4f3f2df06f 1917 Gene3D G3DSA:1.20.1580.10 92 521 3.2E-206 T 12-10-2018 VAPA_1c48560 3295d79debf6717bd30b8a4f3f2df06f 1917 Gene3D G3DSA:3.40.50.300 1286 1546 6.4E-59 T 12-10-2018 VAPA_1c48560 3295d79debf6717bd30b8a4f3f2df06f 1917 SUPERFAMILY SSF52540 1568 1889 3.25E-41 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c48560 3295d79debf6717bd30b8a4f3f2df06f 1917 Gene3D G3DSA:1.10.8.280 288 394 3.2E-206 T 12-10-2018 VAPA_1c48560 3295d79debf6717bd30b8a4f3f2df06f 1917 SUPERFAMILY SSF52540 648 954 1.59E-37 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c48560 3295d79debf6717bd30b8a4f3f2df06f 1917 Gene3D G3DSA:3.30.190.20 132 239 3.2E-206 T 12-10-2018 VAPA_1c48560 3295d79debf6717bd30b8a4f3f2df06f 1917 SUPERFAMILY SSF52540 6 598 1.12E-38 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c48560 3295d79debf6717bd30b8a4f3f2df06f 1917 ProSitePatterns PS00211 ABC transporters family signature. 861 875 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_1c48560 3295d79debf6717bd30b8a4f3f2df06f 1917 Gene3D G3DSA:3.40.50.300 1001 1120 9.1E-23 T 12-10-2018 VAPA_1c48560 3295d79debf6717bd30b8a4f3f2df06f 1917 Gene3D G3DSA:3.40.50.300 8 623 3.2E-206 T 12-10-2018 VAPA_1c48560 3295d79debf6717bd30b8a4f3f2df06f 1917 SUPERFAMILY SSF52540 1018 1517 4.41E-38 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c48560 3295d79debf6717bd30b8a4f3f2df06f 1917 Gene3D G3DSA:1.20.1580.10 719 861 4.8E-130 T 12-10-2018 VAPA_1c48560 3295d79debf6717bd30b8a4f3f2df06f 1917 Gene3D G3DSA:1.20.1580.10 1659 1797 2.1E-131 T 12-10-2018 VAPA_1c48560 3295d79debf6717bd30b8a4f3f2df06f 1917 Gene3D G3DSA:3.40.50.300 644 978 4.8E-130 T 12-10-2018 VAPA_1c48560 3295d79debf6717bd30b8a4f3f2df06f 1917 ProSitePatterns PS00211 ABC transporters family signature. 1797 1811 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_1c48560 3295d79debf6717bd30b8a4f3f2df06f 1917 Gene3D G3DSA:3.40.50.300 1571 1910 2.1E-131 T 12-10-2018 VAPA_1c51250 fa47416717e8416d0ef90fe76d25a1eb 404 SUPERFAMILY SSF52440 3 113 9.06E-30 T 12-10-2018 IPR016185 Pre-ATP-grasp domain superfamily VAPA_1c51250 fa47416717e8416d0ef90fe76d25a1eb 404 Gene3D G3DSA:3.30.1490.20 124 202 1.0E-29 T 12-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 VAPA_1c51250 fa47416717e8416d0ef90fe76d25a1eb 404 SUPERFAMILY SSF56059 114 324 1.03E-54 T 12-10-2018 VAPA_1c51250 fa47416717e8416d0ef90fe76d25a1eb 404 SUPERFAMILY SSF51246 330 400 7.69E-17 T 12-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 VAPA_1c51250 fa47416717e8416d0ef90fe76d25a1eb 404 TIGRFAM TIGR01142 purT: phosphoribosylglycinamide formyltransferase 2 14 400 2.3E-168 T 12-10-2018 IPR005862 Formate-dependent phosphoribosylglycinamide formyltransferase GO:0000287|GO:0004644|GO:0005524|GO:0009152|GO:0016742 VAPA_1c51250 fa47416717e8416d0ef90fe76d25a1eb 404 Gene3D G3DSA:3.40.50.20 2 123 4.3E-50 T 12-10-2018 VAPA_1c51250 fa47416717e8416d0ef90fe76d25a1eb 404 Gene3D G3DSA:3.30.470.20 203 404 2.3E-61 T 12-10-2018 VAPA_1c51250 fa47416717e8416d0ef90fe76d25a1eb 404 Hamap MF_01643 Formate-dependent phosphoribosylglycinamide formyltransferase [purT]. 8 402 50.379 T 12-10-2018 IPR005862 Formate-dependent phosphoribosylglycinamide formyltransferase GO:0000287|GO:0004644|GO:0005524|GO:0009152|GO:0016742 VAPA_1c51250 fa47416717e8416d0ef90fe76d25a1eb 404 Pfam PF02222 ATP-grasp domain 124 305 4.9E-51 T 12-10-2018 IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type VAPA_1c36790 ada9e55f9d909d7e179ace017c857675 192 Gene3D G3DSA:1.20.1290.10 28 191 2.1E-26 T 12-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 VAPA_1c36790 ada9e55f9d909d7e179ace017c857675 192 Pfam PF02627 Carboxymuconolactone decarboxylase family 51 118 5.2E-5 T 12-10-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 VAPA_1c36790 ada9e55f9d909d7e179ace017c857675 192 SUPERFAMILY SSF69118 21 188 2.64E-25 T 12-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 VAPA_1c08680 5b7545149981ec0ab071e47eb4f1d811 294 Gene3D G3DSA:3.40.190.290 93 292 2.8E-43 T 12-10-2018 VAPA_1c08680 5b7545149981ec0ab071e47eb4f1d811 294 Pfam PF03466 LysR substrate binding domain 91 293 1.4E-27 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_1c08680 5b7545149981ec0ab071e47eb4f1d811 294 Gene3D G3DSA:1.10.10.10 1 87 1.3E-20 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c08680 5b7545149981ec0ab071e47eb4f1d811 294 SUPERFAMILY SSF46785 4 108 2.37E-20 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c08680 5b7545149981ec0ab071e47eb4f1d811 294 SUPERFAMILY SSF53850 91 294 9.05E-31 T 12-10-2018 VAPA_1c08680 5b7545149981ec0ab071e47eb4f1d811 294 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 64 3.5E-18 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_2c02280 b5787a68c1bde95d2e4c071b6d1d1144 337 TIGRFAM TIGR00787 dctP: TRAP transporter solute receptor, DctP family 37 288 5.0E-73 T 12-10-2018 IPR004682 TRAP transporter solute receptor, DctP family GO:0030288|GO:0055085 VAPA_2c02280 b5787a68c1bde95d2e4c071b6d1d1144 337 PIRSF PIRSF006470 3 333 5.5E-76 T 12-10-2018 IPR004682 TRAP transporter solute receptor, DctP family GO:0030288|GO:0055085 VAPA_2c02280 b5787a68c1bde95d2e4c071b6d1d1144 337 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 38 310 6.6E-77 T 12-10-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0030288|GO:0055085 VAPA_2c02280 b5787a68c1bde95d2e4c071b6d1d1144 337 Gene3D G3DSA:3.40.190.170 28 337 1.7E-117 T 12-10-2018 IPR038404 TRAP transporter solute receptor DctP superfamily VAPA_1c38750 0fc4606f79f4167d36c43ec50a2b6c76 85 SUPERFAMILY SSF160582 3 72 2.22E-25 T 12-10-2018 IPR038020 MbtH-like domain superfamily VAPA_1c38750 0fc4606f79f4167d36c43ec50a2b6c76 85 Pfam PF03621 MbtH-like protein 3 55 2.0E-19 T 12-10-2018 IPR005153 MbtH-like domain VAPA_1c38750 0fc4606f79f4167d36c43ec50a2b6c76 85 SMART SM00923 4 55 1.6E-24 T 12-10-2018 IPR005153 MbtH-like domain VAPA_1c38750 0fc4606f79f4167d36c43ec50a2b6c76 85 Gene3D G3DSA:3.90.820.10 1 72 2.8E-30 T 12-10-2018 VAPA_1c28180 a6f4ac79c7390482a87a2845863359af 260 SUPERFAMILY SSF51735 6 252 7.71E-60 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c28180 a6f4ac79c7390482a87a2845863359af 260 PIRSF PIRSF000094 1 260 5.8E-110 T 12-10-2018 IPR014358 Enoyl-[acyl-carrier-protein] reductase (NADH) GO:0004318|GO:0006633|GO:0055114 KEGG: 00061+1.3.1.9|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 VAPA_1c28180 a6f4ac79c7390482a87a2845863359af 260 Gene3D G3DSA:3.40.50.720 1 258 2.8E-51 T 12-10-2018 VAPA_1c28180 a6f4ac79c7390482a87a2845863359af 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 180 197 2.1E-6 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c28180 a6f4ac79c7390482a87a2845863359af 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 159 178 2.1E-6 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c28180 a6f4ac79c7390482a87a2845863359af 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 215 235 2.1E-6 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c28180 a6f4ac79c7390482a87a2845863359af 260 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 252 5.2E-83 T 12-10-2018 VAPA_2c08130 ae198fa6ea88eb7b3f1c85f81b0333e2 269 SMART SM00382 43 224 7.2E-20 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_2c08130 ae198fa6ea88eb7b3f1c85f81b0333e2 269 SUPERFAMILY SSF52540 14 222 1.86E-64 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_2c08130 ae198fa6ea88eb7b3f1c85f81b0333e2 269 Pfam PF00005 ABC transporter 34 173 2.7E-31 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_2c08130 ae198fa6ea88eb7b3f1c85f81b0333e2 269 Gene3D G3DSA:3.40.50.300 14 251 4.3E-67 T 12-10-2018 VAPA_2c08130 ae198fa6ea88eb7b3f1c85f81b0333e2 269 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_1c15160 9f7bd65ba2be0bbb35f8a14dc3c15666 317 Gene3D G3DSA:3.40.190.290 104 312 3.2E-33 T 12-10-2018 VAPA_1c15160 9f7bd65ba2be0bbb35f8a14dc3c15666 317 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 15 73 4.4E-16 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c15160 9f7bd65ba2be0bbb35f8a14dc3c15666 317 SUPERFAMILY SSF53850 99 306 9.12E-38 T 12-10-2018 VAPA_1c15160 9f7bd65ba2be0bbb35f8a14dc3c15666 317 SUPERFAMILY SSF46785 10 121 3.32E-22 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c15160 9f7bd65ba2be0bbb35f8a14dc3c15666 317 Gene3D G3DSA:1.10.10.10 12 103 3.6E-22 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c15160 9f7bd65ba2be0bbb35f8a14dc3c15666 317 Pfam PF03466 LysR substrate binding domain 98 303 1.3E-31 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_1c44990 9f87c07974ac1adec06169eee02660a9 192 Hamap MF_00105 Transcription elongation factor GreA [greA]. 29 182 26.876 T 12-10-2018 IPR028624 Transcription elongation factor GreA/GreB GO:0003677|GO:0032784|GO:0070063 VAPA_1c44990 9f87c07974ac1adec06169eee02660a9 192 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 110 183 2.0E-22 T 12-10-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 VAPA_1c44990 9f87c07974ac1adec06169eee02660a9 192 Gene3D G3DSA:3.10.50.30 106 186 1.9E-23 T 12-10-2018 IPR036953 Transcription elongation factor GreA/GreB, C-terminal domain superfamily GO:0003677|GO:0032784 VAPA_1c44990 9f87c07974ac1adec06169eee02660a9 192 SUPERFAMILY SSF54534 109 183 1.26E-18 T 12-10-2018 VAPA_1c44990 9f87c07974ac1adec06169eee02660a9 192 Pfam PF03449 Transcription elongation factor, N-terminal 31 101 3.7E-24 T 12-10-2018 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 VAPA_1c44990 9f87c07974ac1adec06169eee02660a9 192 TIGRFAM TIGR01461 greB: transcription elongation factor GreB 30 184 3.7E-62 T 12-10-2018 IPR006358 Transcription elongation factor GreB GO:0003677|GO:0032784 VAPA_1c44990 9f87c07974ac1adec06169eee02660a9 192 PIRSF PIRSF006092 27 185 7.3E-41 T 12-10-2018 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 VAPA_1c44990 9f87c07974ac1adec06169eee02660a9 192 Gene3D G3DSA:1.10.287.180 29 103 2.7E-26 T 12-10-2018 IPR036805 Transcription elongation factor, GreA/GreB, N-terminal domain superfamily GO:0003677|GO:0032784 VAPA_1c44990 9f87c07974ac1adec06169eee02660a9 192 ProSitePatterns PS00830 Prokaryotic transcription elongation factors signature 2. 147 163 - T 12-10-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 VAPA_1c44990 9f87c07974ac1adec06169eee02660a9 192 SUPERFAMILY SSF46557 30 105 5.1E-26 T 12-10-2018 IPR036805 Transcription elongation factor, GreA/GreB, N-terminal domain superfamily GO:0003677|GO:0032784 VAPA_1c44990 9f87c07974ac1adec06169eee02660a9 192 Hamap MF_00930 Transcription elongation factor GreB [greB]. 28 184 50.743 T 12-10-2018 IPR006358 Transcription elongation factor GreB GO:0003677|GO:0032784 VAPA_1c44990 9f87c07974ac1adec06169eee02660a9 192 ProSitePatterns PS00829 Prokaryotic transcription elongation factors signature 1. 44 75 - T 12-10-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 VAPA_1c36230 ed56d5715397f2d9b1a2cd464a987982 771 PIRSF PIRSF005499 3 727 6.6E-294 T 12-10-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 VAPA_1c36230 ed56d5715397f2d9b1a2cd464a987982 771 SMART SM00322 554 619 2.2E-13 T 12-10-2018 IPR004087 K Homology domain GO:0003676 VAPA_1c36230 ed56d5715397f2d9b1a2cd464a987982 771 SUPERFAMILY SSF55666 455 562 1.66E-28 T 12-10-2018 IPR036345 Exoribonuclease, PH domain 2 superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 VAPA_1c36230 ed56d5715397f2d9b1a2cd464a987982 771 Hamap MF_01595 Polyribonucleotide nucleotidyltransferase [pnp]. 5 695 29.762 T 12-10-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 VAPA_1c36230 ed56d5715397f2d9b1a2cd464a987982 771 Pfam PF01138 3' exoribonuclease family, domain 1 18 146 8.2E-17 T 12-10-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 VAPA_1c36230 ed56d5715397f2d9b1a2cd464a987982 771 Pfam PF01138 3' exoribonuclease family, domain 1 326 458 6.6E-20 T 12-10-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 VAPA_1c36230 ed56d5715397f2d9b1a2cd464a987982 771 Pfam PF00575 S1 RNA binding domain 621 692 3.1E-16 T 12-10-2018 IPR003029 S1 domain GO:0003676 VAPA_1c36230 ed56d5715397f2d9b1a2cd464a987982 771 Gene3D G3DSA:3.30.1370.10 552 623 1.2E-21 T 12-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 VAPA_1c36230 ed56d5715397f2d9b1a2cd464a987982 771 SUPERFAMILY SSF50249 622 704 1.79E-20 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold VAPA_1c36230 ed56d5715397f2d9b1a2cd464a987982 771 Gene3D G3DSA:3.30.230.70 1 231 2.3E-75 T 12-10-2018 IPR027408 PNPase/RNase PH domain superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 VAPA_1c36230 ed56d5715397f2d9b1a2cd464a987982 771 Gene3D G3DSA:2.40.50.140 624 696 1.7E-27 T 12-10-2018 VAPA_1c36230 ed56d5715397f2d9b1a2cd464a987982 771 SMART SM00316 622 692 8.0E-24 T 12-10-2018 IPR022967 RNA-binding domain, S1 VAPA_1c36230 ed56d5715397f2d9b1a2cd464a987982 771 Pfam PF00013 KH domain 558 616 2.4E-12 T 12-10-2018 IPR004088 K Homology domain, type 1 GO:0003723 VAPA_1c36230 ed56d5715397f2d9b1a2cd464a987982 771 Pfam PF03725 3' exoribonuclease family, domain 2 463 531 4.2E-5 T 12-10-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 VAPA_1c36230 ed56d5715397f2d9b1a2cd464a987982 771 Pfam PF03725 3' exoribonuclease family, domain 2 149 212 2.9E-8 T 12-10-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 VAPA_1c36230 ed56d5715397f2d9b1a2cd464a987982 771 Gene3D G3DSA:3.30.230.70 235 551 3.6E-115 T 12-10-2018 IPR027408 PNPase/RNase PH domain superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 VAPA_1c36230 ed56d5715397f2d9b1a2cd464a987982 771 Pfam PF03726 Polyribonucleotide nucleotidyltransferase, RNA binding domain 245 322 1.7E-18 T 12-10-2018 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 VAPA_1c36230 ed56d5715397f2d9b1a2cd464a987982 771 SUPERFAMILY SSF55666 147 237 5.13E-27 T 12-10-2018 IPR036345 Exoribonuclease, PH domain 2 superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 VAPA_1c36230 ed56d5715397f2d9b1a2cd464a987982 771 SUPERFAMILY SSF54211 294 490 5.06E-47 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold VAPA_1c36230 ed56d5715397f2d9b1a2cd464a987982 771 SUPERFAMILY SSF54211 4 146 2.94E-49 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold VAPA_1c36230 ed56d5715397f2d9b1a2cd464a987982 771 TIGRFAM TIGR03591 polynuc_phos: polyribonucleotide nucleotidyltransferase 12 693 0.0 T 12-10-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 VAPA_1c36230 ed56d5715397f2d9b1a2cd464a987982 771 SUPERFAMILY SSF54791 557 641 3.68E-23 T 12-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 VAPA_1c54750 782e811fec920a28d0a10ff81df0ea19 534 Gene3D G3DSA:3.50.50.60 54 393 7.0E-30 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c54750 782e811fec920a28d0a10ff81df0ea19 534 Pfam PF01593 Flavin containing amine oxidoreductase 66 388 1.1E-15 T 12-10-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 VAPA_1c54750 782e811fec920a28d0a10ff81df0ea19 534 SUPERFAMILY SSF51905 55 531 4.1E-35 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c33370 0d290578bbcbceed9b3ade9ac2bd4091 178 SUPERFAMILY SSF55961 4 176 3.8E-43 T 12-10-2018 VAPA_1c33370 0d290578bbcbceed9b3ade9ac2bd4091 178 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 22 153 1.5E-19 T 12-10-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like VAPA_1c33370 0d290578bbcbceed9b3ade9ac2bd4091 178 Gene3D G3DSA:3.30.530.20 7 178 2.6E-46 T 12-10-2018 IPR023393 START-like domain superfamily VAPA_1c17050 146928bd7d017545b530f3e7f45bf8c9 118 SUPERFAMILY SSF47781 20 77 1.53E-9 T 12-10-2018 IPR010994 RuvA domain 2-like VAPA_1c17050 146928bd7d017545b530f3e7f45bf8c9 118 Gene3D G3DSA:1.10.150.320 7 78 1.8E-11 T 12-10-2018 VAPA_1c17050 146928bd7d017545b530f3e7f45bf8c9 118 Pfam PF12836 Helix-hairpin-helix motif 19 75 1.9E-9 T 12-10-2018 VAPA_1c28750 7ce549cde3f72f385aaf68d076710c18 569 SUPERFAMILY SSF54637 469 566 2.94E-11 T 12-10-2018 IPR029069 HotDog domain superfamily VAPA_1c28750 7ce549cde3f72f385aaf68d076710c18 569 Pfam PF07977 FabA-like domain 470 537 1.7E-5 T 12-10-2018 IPR013114 Beta-hydroxydecanoyl thiol ester dehydrase, FabA/FabZ KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 VAPA_1c28750 7ce549cde3f72f385aaf68d076710c18 569 Gene3D G3DSA:3.40.50.12780 14 314 9.5E-19 T 12-10-2018 VAPA_1c28750 7ce549cde3f72f385aaf68d076710c18 569 SUPERFAMILY SSF56801 11 456 6.02E-42 T 12-10-2018 VAPA_1c28750 7ce549cde3f72f385aaf68d076710c18 569 Pfam PF00501 AMP-binding enzyme 26 296 1.5E-13 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 VAPA_1c28750 7ce549cde3f72f385aaf68d076710c18 569 Gene3D G3DSA:3.30.300.30 357 453 1.4E-13 T 12-10-2018 VAPA_1c28750 7ce549cde3f72f385aaf68d076710c18 569 Pfam PF13193 AMP-binding enzyme C-terminal domain 378 444 3.6E-6 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain VAPA_1c28750 7ce549cde3f72f385aaf68d076710c18 569 Gene3D G3DSA:3.10.129.10 454 565 8.1E-17 T 12-10-2018 VAPA_1c19680 80bbadcea923eaf37c906603005ab673 119 SUPERFAMILY SSF74731 2 116 1.96E-48 T 12-10-2018 IPR035566 Ribosomal protein L20, C-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 VAPA_1c19680 80bbadcea923eaf37c906603005ab673 119 Pfam PF00453 Ribosomal protein L20 3 107 8.2E-48 T 12-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 VAPA_1c19680 80bbadcea923eaf37c906603005ab673 119 Hamap MF_00382 50S ribosomal protein L20 [rplT]. 2 115 29.802 T 12-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 VAPA_1c19680 80bbadcea923eaf37c906603005ab673 119 ProSitePatterns PS00937 Ribosomal protein L20 signature. 54 70 - T 12-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 VAPA_1c19680 80bbadcea923eaf37c906603005ab673 119 PRINTS PR00062 Ribosomal protein L20 signature 12 41 5.9E-39 T 12-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 VAPA_1c19680 80bbadcea923eaf37c906603005ab673 119 PRINTS PR00062 Ribosomal protein L20 signature 75 101 5.9E-39 T 12-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 VAPA_1c19680 80bbadcea923eaf37c906603005ab673 119 PRINTS PR00062 Ribosomal protein L20 signature 42 71 5.9E-39 T 12-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 VAPA_1c19680 80bbadcea923eaf37c906603005ab673 119 Gene3D G3DSA:1.10.720.90 2 55 8.9E-26 T 12-10-2018 VAPA_1c19680 80bbadcea923eaf37c906603005ab673 119 TIGRFAM TIGR01032 rplT_bact: ribosomal protein bL20 1 114 3.3E-48 T 12-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 VAPA_1c19680 80bbadcea923eaf37c906603005ab673 119 Gene3D G3DSA:1.10.1900.20 56 119 8.9E-28 T 12-10-2018 IPR035566 Ribosomal protein L20, C-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 VAPA_1c19680 80bbadcea923eaf37c906603005ab673 119 ProDom PD002389 RIBOSOMAL RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN L20 50S L20 CHLOROPLAST BACTERIAL ORGANELLE 20 70 1.0E-21 T 12-10-2018 VAPA_1c28000 3c88081ae4db82af865d412fbcd5bd65 148 SUPERFAMILY SSF55961 1 146 1.22E-35 T 12-10-2018 VAPA_1c28000 3c88081ae4db82af865d412fbcd5bd65 148 Pfam PF03364 Polyketide cyclase / dehydrase and lipid transport 12 137 9.2E-32 T 12-10-2018 IPR005031 Coenzyme Q-binding protein COQ10, START domain Reactome: R-HSA-611105 VAPA_1c28000 3c88081ae4db82af865d412fbcd5bd65 148 Gene3D G3DSA:3.30.530.20 1 147 8.7E-41 T 12-10-2018 IPR023393 START-like domain superfamily VAPA_1c48490 dc669f8fe80585562168cb8c007f187b 430 SUPERFAMILY SSF53383 26 427 2.78E-130 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase VAPA_1c48490 dc669f8fe80585562168cb8c007f187b 430 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 241 278 - T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 VAPA_1c48490 dc669f8fe80585562168cb8c007f187b 430 Pfam PF00202 Aminotransferase class-III 21 423 3.0E-127 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 VAPA_1c48490 dc669f8fe80585562168cb8c007f187b 430 TIGRFAM TIGR00700 GABAtrnsam: 4-aminobutyrate transaminase 15 427 2.5E-174 T 12-10-2018 IPR004632 4-aminobutyrate aminotransferase, bacterial GO:0003867|GO:0009448 VAPA_1c48490 dc669f8fe80585562168cb8c007f187b 430 PIRSF PIRSF000521 30 135 0.0017 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 VAPA_1c48490 dc669f8fe80585562168cb8c007f187b 430 PIRSF PIRSF000521 129 429 4.1E-38 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 VAPA_1c48490 dc669f8fe80585562168cb8c007f187b 430 Gene3D G3DSA:3.90.1150.10 30 422 4.4E-158 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 VAPA_1c48490 dc669f8fe80585562168cb8c007f187b 430 Gene3D G3DSA:3.40.640.10 64 323 4.4E-158 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 VAPA_1c52990 0a89c5496c6aa225746286b0f4da44ca 323 Gene3D G3DSA:3.40.190.150 27 313 1.2E-106 T 12-10-2018 VAPA_1c52990 0a89c5496c6aa225746286b0f4da44ca 323 Gene3D G3DSA:3.40.190.10 125 248 1.2E-106 T 12-10-2018 VAPA_1c52990 0a89c5496c6aa225746286b0f4da44ca 323 PIRSF PIRSF017082 1 322 1.7E-79 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c52990 0a89c5496c6aa225746286b0f4da44ca 323 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 47 319 2.2E-88 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c52990 0a89c5496c6aa225746286b0f4da44ca 323 SUPERFAMILY SSF53850 112 290 1.93E-14 T 12-10-2018 VAPA_1c54090 05c7a28c638c49ac74eff0afcfa825d3 209 SMART SM00317 11 129 8.5E-31 T 12-10-2018 IPR001214 SET domain GO:0005515 VAPA_1c54090 05c7a28c638c49ac74eff0afcfa825d3 209 Gene3D G3DSA:2.170.270.10 5 175 4.7E-44 T 12-10-2018 VAPA_1c54090 05c7a28c638c49ac74eff0afcfa825d3 209 Pfam PF00856 SET domain 22 123 1.1E-16 T 12-10-2018 IPR001214 SET domain GO:0005515 VAPA_1c54090 05c7a28c638c49ac74eff0afcfa825d3 209 SUPERFAMILY SSF82199 12 149 6.02E-44 T 12-10-2018 VAPA_1c41840 2ca656e04ccd427842363167e23e8479 139 Gene3D G3DSA:1.10.490.10 9 139 2.3E-41 T 12-10-2018 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 VAPA_1c41840 2ca656e04ccd427842363167e23e8479 139 SUPERFAMILY SSF46458 10 137 4.11E-33 T 12-10-2018 IPR009050 Globin-like superfamily VAPA_1c41840 2ca656e04ccd427842363167e23e8479 139 Pfam PF01152 Bacterial-like globin 13 135 9.4E-39 T 12-10-2018 IPR001486 Truncated hemoglobin GO:0019825 VAPA_1c11110 5414afcdffcc9062ff970a7869b017ef 855 Pfam PF08245 Mur ligase middle domain 474 685 9.7E-21 T 12-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 VAPA_1c11110 5414afcdffcc9062ff970a7869b017ef 855 ProSitePatterns PS01011 Folylpolyglutamate synthase signature 1. 472 495 - T 12-10-2018 IPR018109 Folylpolyglutamate synthetase, conserved site GO:0004326|GO:0005524|GO:0009396 Reactome: R-HSA-196757 VAPA_1c11110 5414afcdffcc9062ff970a7869b017ef 855 SMART SM01209 203 415 0.0073 T 12-10-2018 VAPA_1c11110 5414afcdffcc9062ff970a7869b017ef 855 Pfam PF02875 Mur ligase family, glutamate ligase domain 709 788 9.6E-13 T 12-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 VAPA_1c11110 5414afcdffcc9062ff970a7869b017ef 855 Gene3D G3DSA:3.90.190.20 711 853 8.9E-18 T 12-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 VAPA_1c11110 5414afcdffcc9062ff970a7869b017ef 855 Gene3D G3DSA:3.30.470.20 362 461 3.2E-11 T 12-10-2018 VAPA_1c11110 5414afcdffcc9062ff970a7869b017ef 855 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 204 287 2.7E-7 T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 VAPA_1c11110 5414afcdffcc9062ff970a7869b017ef 855 SUPERFAMILY SSF53623 432 722 1.7E-41 T 12-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 VAPA_1c11110 5414afcdffcc9062ff970a7869b017ef 855 Gene3D G3DSA:3.40.1190.10 466 703 1.3E-38 T 12-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 VAPA_1c11110 5414afcdffcc9062ff970a7869b017ef 855 Gene3D G3DSA:3.30.1490.20 204 283 2.5E-17 T 12-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 VAPA_1c11110 5414afcdffcc9062ff970a7869b017ef 855 SUPERFAMILY SSF56059 204 460 3.01E-34 T 12-10-2018 VAPA_1c11110 5414afcdffcc9062ff970a7869b017ef 855 TIGRFAM TIGR02068 cya_phycin_syn: cyanophycin synthetase 2 852 0.0 T 12-10-2018 IPR011810 Cyanophycin synthetase GO:0005524|GO:0009059|GO:0016874 MetaCyc: PWY-7052 VAPA_1c11110 5414afcdffcc9062ff970a7869b017ef 855 SUPERFAMILY SSF53244 709 837 7.78E-23 T 12-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 VAPA_1c06830 6408fb3a2b913f55b9736cccf37ae121 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 53 1.6E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c06830 6408fb3a2b913f55b9736cccf37ae121 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 32 42 1.6E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c06830 6408fb3a2b913f55b9736cccf37ae121 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 21 32 1.6E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c06830 6408fb3a2b913f55b9736cccf37ae121 301 Gene3D G3DSA:1.10.10.10 5 91 1.2E-21 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c06830 6408fb3a2b913f55b9736cccf37ae121 301 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 10 65 2.4E-16 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c06830 6408fb3a2b913f55b9736cccf37ae121 301 Pfam PF03466 LysR substrate binding domain 92 294 9.0E-42 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_1c06830 6408fb3a2b913f55b9736cccf37ae121 301 Gene3D G3DSA:3.40.190.290 93 296 5.5E-57 T 12-10-2018 VAPA_1c06830 6408fb3a2b913f55b9736cccf37ae121 301 SUPERFAMILY SSF46785 8 87 2.29E-18 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c06830 6408fb3a2b913f55b9736cccf37ae121 301 SUPERFAMILY SSF53850 92 297 2.35E-45 T 12-10-2018 VAPA_1c09360 20d5a862e343f0be2511402b87e27d48 557 Pfam PF00753 Metallo-beta-lactamase superfamily 304 467 3.2E-16 T 12-10-2018 IPR001279 Metallo-beta-lactamase VAPA_1c09360 20d5a862e343f0be2511402b87e27d48 557 SMART SM00849 304 483 1.3E-25 T 12-10-2018 IPR001279 Metallo-beta-lactamase VAPA_1c09360 20d5a862e343f0be2511402b87e27d48 557 Gene3D G3DSA:1.10.10.10 489 554 4.3E-5 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c09360 20d5a862e343f0be2511402b87e27d48 557 SUPERFAMILY SSF55811 10 209 3.54E-17 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 VAPA_1c09360 20d5a862e343f0be2511402b87e27d48 557 SUPERFAMILY SSF56281 283 550 2.36E-46 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like VAPA_1c09360 20d5a862e343f0be2511402b87e27d48 557 Gene3D G3DSA:3.90.79.10 12 234 1.2E-55 T 12-10-2018 VAPA_1c09360 20d5a862e343f0be2511402b87e27d48 557 Gene3D G3DSA:3.60.15.10 278 488 2.3E-40 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like VAPA_1c43670 e9a8f57776425f7e2d62372f70a7d56b 427 Pfam PF00571 CBS domain 289 334 0.0061 T 12-10-2018 IPR000644 CBS domain VAPA_1c43670 e9a8f57776425f7e2d62372f70a7d56b 427 Gene3D G3DSA:3.30.465.10 349 427 1.3E-30 T 12-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 VAPA_1c43670 e9a8f57776425f7e2d62372f70a7d56b 427 SMART SM01091 348 427 1.9E-27 T 12-10-2018 IPR005170 Transporter-associated domain VAPA_1c43670 e9a8f57776425f7e2d62372f70a7d56b 427 SUPERFAMILY SSF56176 343 426 6.54E-24 T 12-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 VAPA_1c43670 e9a8f57776425f7e2d62372f70a7d56b 427 Pfam PF03471 Transporter associated domain 349 426 1.5E-22 T 12-10-2018 IPR005170 Transporter-associated domain VAPA_1c43670 e9a8f57776425f7e2d62372f70a7d56b 427 Gene3D G3DSA:3.10.580.10 195 348 1.1E-33 T 12-10-2018 VAPA_1c43670 e9a8f57776425f7e2d62372f70a7d56b 427 Pfam PF01595 Domain of unknown function DUF21 8 197 7.4E-39 T 12-10-2018 IPR002550 CNNM, transmembrane domain VAPA_1c43670 e9a8f57776425f7e2d62372f70a7d56b 427 SUPERFAMILY SSF54631 202 337 6.76E-21 T 12-10-2018 VAPA_2c05190 af1a31429ca7a0ffa8411ebfbe1aac7e 111 SUPERFAMILY SSF51182 26 105 2.57E-14 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily VAPA_2c05190 af1a31429ca7a0ffa8411ebfbe1aac7e 111 Gene3D G3DSA:2.60.120.10 1 107 2.4E-22 T 12-10-2018 IPR014710 RmlC-like jelly roll fold VAPA_1c02400 316779680a06672a88618b5917646fc7 220 Pfam PF12059 Protein of unknown function (DUF3540) 28 220 9.3E-58 T 12-10-2018 IPR021927 Protein of unknown function DUF3540 VAPA_1c09150 6e38c35bd9748733e33668180878f9d9 317 SUPERFAMILY SSF161098 90 302 9.03E-19 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c09150 6e38c35bd9748733e33668180878f9d9 317 Gene3D G3DSA:1.10.3720.10 89 311 2.4E-25 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c09150 6e38c35bd9748733e33668180878f9d9 317 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 315 1.5E-41 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 VAPA_1c15740 77932af19fff48c0aeae19072ec60a02 421 Gene3D G3DSA:3.30.2010.10 206 288 2.8E-30 T 12-10-2018 VAPA_1c15740 77932af19fff48c0aeae19072ec60a02 421 Pfam PF01435 Peptidase family M48 210 419 3.4E-37 T 12-10-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 VAPA_1c15740 77932af19fff48c0aeae19072ec60a02 421 Pfam PF16491 CAAX prenyl protease N-terminal, five membrane helices 29 207 2.0E-58 T 12-10-2018 IPR032456 CAAX prenyl protease 1, N-terminal KEGG: 00900+3.4.24.84 VAPA_1c30380 b4a17d58388278e2430367d74c3d11e1 433 Pfam PF11700 Vacuole effluxer Atg22 like 153 429 5.0E-35 T 12-10-2018 IPR024671 Autophagy-related protein 22-like VAPA_1c30380 b4a17d58388278e2430367d74c3d11e1 433 Pfam PF11700 Vacuole effluxer Atg22 like 63 148 4.3E-6 T 12-10-2018 IPR024671 Autophagy-related protein 22-like VAPA_1c30380 b4a17d58388278e2430367d74c3d11e1 433 Gene3D G3DSA:1.20.1250.20 18 420 1.1E-27 T 12-10-2018 VAPA_1c30380 b4a17d58388278e2430367d74c3d11e1 433 SUPERFAMILY SSF103473 26 425 2.75E-37 T 12-10-2018 IPR036259 MFS transporter superfamily VAPA_2c02930 953d571f0e570f0b2dda23c3b946e939 474 Pfam PF12831 FAD dependent oxidoreductase 24 456 1.2E-82 T 12-10-2018 IPR039649 Digeranylgeranylglycerophospholipid reductase, N-terminal VAPA_2c02930 953d571f0e570f0b2dda23c3b946e939 474 SUPERFAMILY SSF51905 21 436 4.16E-28 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_2c02930 953d571f0e570f0b2dda23c3b946e939 474 Gene3D G3DSA:3.50.50.60 20 205 5.6E-17 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c24560 8348b745502d556b0b17cfe246017c9c 230 SUPERFAMILY SSF46894 128 225 2.27E-28 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 VAPA_1c24560 8348b745502d556b0b17cfe246017c9c 230 Pfam PF00486 Transcriptional regulatory protein, C terminal 152 224 8.3E-26 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 VAPA_1c24560 8348b745502d556b0b17cfe246017c9c 230 Gene3D G3DSA:3.40.50.2300 1 128 2.9E-37 T 12-10-2018 VAPA_1c24560 8348b745502d556b0b17cfe246017c9c 230 Gene3D G3DSA:1.10.10.10 129 227 2.7E-34 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c24560 8348b745502d556b0b17cfe246017c9c 230 TIGRFAM TIGR02154 PhoB: phosphate regulon transcriptional regulatory protein PhoB 4 224 3.2E-99 T 12-10-2018 IPR011879 Signal transduction response regulator, phosphate regulon transcriptional regulatory protein PhoB GO:0000156|GO:0000160|GO:0003677|GO:0006817 VAPA_1c24560 8348b745502d556b0b17cfe246017c9c 230 SMART SM00448 4 117 1.8E-41 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_1c24560 8348b745502d556b0b17cfe246017c9c 230 SUPERFAMILY SSF52172 2 126 1.18E-41 T 12-10-2018 IPR011006 CheY-like superfamily VAPA_1c24560 8348b745502d556b0b17cfe246017c9c 230 Pfam PF00072 Response regulator receiver domain 6 118 1.6E-24 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_1c24560 8348b745502d556b0b17cfe246017c9c 230 SMART SM00862 151 224 3.2E-26 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 VAPA_1c52590 abd95c42ec7284fc736a0621501066f6 709 SMART SM00490 520 601 6.6E-22 T 12-10-2018 IPR001650 Helicase, C-terminal VAPA_1c52590 abd95c42ec7284fc736a0621501066f6 709 Gene3D G3DSA:3.40.50.300 215 461 3.2E-81 T 12-10-2018 VAPA_1c52590 abd95c42ec7284fc736a0621501066f6 709 Gene3D G3DSA:2.40.50.140 58 149 7.2E-7 T 12-10-2018 VAPA_1c52590 abd95c42ec7284fc736a0621501066f6 709 SUPERFAMILY SSF52540 326 614 7.99E-52 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c52590 abd95c42ec7284fc736a0621501066f6 709 Pfam PF00270 DEAD/DEAH box helicase 302 445 1.4E-13 T 12-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 VAPA_1c52590 abd95c42ec7284fc736a0621501066f6 709 SMART SM00487 274 471 2.3E-25 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain VAPA_1c52590 abd95c42ec7284fc736a0621501066f6 709 Pfam PF00271 Helicase conserved C-terminal domain 490 600 1.2E-16 T 12-10-2018 IPR001650 Helicase, C-terminal VAPA_1c52590 abd95c42ec7284fc736a0621501066f6 709 SUPERFAMILY SSF50249 32 178 3.68E-22 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold VAPA_1c52590 abd95c42ec7284fc736a0621501066f6 709 Gene3D G3DSA:3.40.50.300 469 646 6.3E-56 T 12-10-2018 VAPA_1c52590 abd95c42ec7284fc736a0621501066f6 709 TIGRFAM TIGR00643 recG: ATP-dependent DNA helicase RecG 46 680 3.8E-203 T 12-10-2018 IPR004609 ATP-dependent DNA helicase RecG GO:0004003|GO:0006281|GO:0006310 VAPA_1c52590 abd95c42ec7284fc736a0621501066f6 709 Pfam PF17191 RecG wedge domain 33 177 8.1E-11 T 12-10-2018 IPR033454 RecG, wedge domain VAPA_1c10260 bd6f0b27f7f7464121d9ffba900e5224 215 SMART SM00855 6 160 2.7E-21 T 12-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 VAPA_1c10260 bd6f0b27f7f7464121d9ffba900e5224 215 Gene3D G3DSA:3.40.50.1240 4 209 2.6E-61 T 12-10-2018 IPR029033 Histidine phosphatase superfamily VAPA_1c10260 bd6f0b27f7f7464121d9ffba900e5224 215 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 7 199 5.3E-63 T 12-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 VAPA_1c10260 bd6f0b27f7f7464121d9ffba900e5224 215 PIRSF PIRSF000709 5 167 1.2E-8 T 12-10-2018 VAPA_1c10260 bd6f0b27f7f7464121d9ffba900e5224 215 SUPERFAMILY SSF53254 5 204 4.16E-57 T 12-10-2018 IPR029033 Histidine phosphatase superfamily VAPA_1c52840 63843610767a0e417369d804b863aae3 182 TIGRFAM TIGR01162 purE: phosphoribosylaminoimidazole carboxylase, catalytic subunit 7 155 4.5E-62 T 12-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 VAPA_1c52840 63843610767a0e417369d804b863aae3 182 SUPERFAMILY SSF52255 6 158 1.44E-62 T 12-10-2018 IPR035893 PurE domain superfamily Reactome: R-HSA-73817 VAPA_1c52840 63843610767a0e417369d804b863aae3 182 Pfam PF00731 AIR carboxylase 6 153 3.7E-62 T 12-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 VAPA_1c52840 63843610767a0e417369d804b863aae3 182 PIRSF PIRSF001338 2 161 3.3E-64 T 12-10-2018 IPR024694 PurE, prokaryotic type GO:0006189 KEGG: 00230+5.4.99.18|MetaCyc: PWY-6123|MetaCyc: PWY-7234 VAPA_1c52840 63843610767a0e417369d804b863aae3 182 SMART SM01001 5 156 2.5E-95 T 12-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 VAPA_1c52840 63843610767a0e417369d804b863aae3 182 Gene3D G3DSA:3.40.50.7700 1 165 8.4E-71 T 12-10-2018 IPR035893 PurE domain superfamily Reactome: R-HSA-73817 VAPA_1c52840 63843610767a0e417369d804b863aae3 182 Hamap MF_01929 N5-carboxyaminoimidazole ribonucleotide mutase [purE]. 7 160 31.069 T 12-10-2018 IPR033747 Class I PurE VAPA_2c08590 98a91e8414c7f3a750986716183ff0cb 335 SUPERFAMILY SSF143631 37 324 5.23E-71 T 12-10-2018 IPR003374 ApbE-like superfamily VAPA_2c08590 98a91e8414c7f3a750986716183ff0cb 335 Pfam PF02424 ApbE family 40 310 1.9E-61 T 12-10-2018 IPR024932 Flavin transferase ApbE GO:0017013 VAPA_2c08590 98a91e8414c7f3a750986716183ff0cb 335 Gene3D G3DSA:3.10.520.20 31 331 1.3E-73 T 12-10-2018 VAPA_2c08590 98a91e8414c7f3a750986716183ff0cb 335 PIRSF PIRSF006268 1 330 2.5E-63 T 12-10-2018 IPR024932 Flavin transferase ApbE GO:0017013 VAPA_1c53500 a1ad6f066b9b60d3956aec91286c7940 931 Hamap MF_00802 Bifunctional glutamine synthetase adenylyltransferase/adenylyl-removing enzyme [glnE]. 24 931 16.985 T 12-10-2018 IPR023057 Bifunctional glutamine synthetase adenylyltransferase/adenylyl-removing enzyme GO:0008882 VAPA_1c53500 a1ad6f066b9b60d3956aec91286c7940 931 Gene3D G3DSA:1.20.120.330 800 931 3.9E-34 T 12-10-2018 VAPA_1c53500 a1ad6f066b9b60d3956aec91286c7940 931 SUPERFAMILY SSF81593 803 931 1.26E-25 T 12-10-2018 VAPA_1c53500 a1ad6f066b9b60d3956aec91286c7940 931 Pfam PF08335 GlnD PII-uridylyltransferase 827 903 5.5E-8 T 12-10-2018 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 VAPA_1c53500 a1ad6f066b9b60d3956aec91286c7940 931 Pfam PF08335 GlnD PII-uridylyltransferase 295 438 2.7E-40 T 12-10-2018 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 VAPA_1c53500 a1ad6f066b9b60d3956aec91286c7940 931 Gene3D G3DSA:3.30.460.100 560 799 1.6E-72 T 12-10-2018 VAPA_1c53500 a1ad6f066b9b60d3956aec91286c7940 931 Gene3D G3DSA:3.30.460.100 32 273 2.3E-57 T 12-10-2018 VAPA_1c53500 a1ad6f066b9b60d3956aec91286c7940 931 Pfam PF03710 Glutamate-ammonia ligase adenylyltransferase 60 260 4.0E-51 T 12-10-2018 IPR005190 Glutamate-ammonia ligase adenylyltransferase, repeated domain GO:0008882 VAPA_1c53500 a1ad6f066b9b60d3956aec91286c7940 931 Pfam PF03710 Glutamate-ammonia ligase adenylyltransferase 551 793 5.4E-57 T 12-10-2018 IPR005190 Glutamate-ammonia ligase adenylyltransferase, repeated domain GO:0008882 VAPA_1c53500 a1ad6f066b9b60d3956aec91286c7940 931 Gene3D G3DSA:1.20.120.330 282 442 2.1E-53 T 12-10-2018 VAPA_1c53500 a1ad6f066b9b60d3956aec91286c7940 931 SUPERFAMILY SSF81593 284 438 4.0E-41 T 12-10-2018 VAPA_1c53500 a1ad6f066b9b60d3956aec91286c7940 931 SUPERFAMILY SSF81301 11 267 1.63E-59 T 12-10-2018 VAPA_1c53500 a1ad6f066b9b60d3956aec91286c7940 931 SUPERFAMILY SSF81301 524 803 5.34E-68 T 12-10-2018 VAPA_1c16740 a29ea629635b4001b6c0755476afb728 315 Gene3D G3DSA:1.10.10.10 23 113 2.7E-17 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c16740 a29ea629635b4001b6c0755476afb728 315 Gene3D G3DSA:3.40.190.290 114 314 1.4E-16 T 12-10-2018 VAPA_1c16740 a29ea629635b4001b6c0755476afb728 315 Pfam PF03466 LysR substrate binding domain 113 313 5.6E-24 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_1c16740 a29ea629635b4001b6c0755476afb728 315 SUPERFAMILY SSF53850 105 313 4.19E-23 T 12-10-2018 VAPA_1c16740 a29ea629635b4001b6c0755476afb728 315 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 25 84 2.2E-12 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c16740 a29ea629635b4001b6c0755476afb728 315 SUPERFAMILY SSF46785 23 109 1.39E-16 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c45260 dcb1a6e1b7f272edad2d58750a969bc2 470 Gene3D G3DSA:3.90.1300.10 4 469 1.9E-127 T 12-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 VAPA_1c45260 dcb1a6e1b7f272edad2d58750a969bc2 470 SUPERFAMILY SSF75304 8 467 5.76E-118 T 12-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 VAPA_1c45260 dcb1a6e1b7f272edad2d58750a969bc2 470 Pfam PF01425 Amidase 30 450 1.7E-85 T 12-10-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 VAPA_2c05810 b964eb1e52433b7ee1f2c7640aab76dd 323 Gene3D G3DSA:3.40.190.10 125 248 1.4E-108 T 12-10-2018 VAPA_2c05810 b964eb1e52433b7ee1f2c7640aab76dd 323 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 47 319 3.8E-83 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_2c05810 b964eb1e52433b7ee1f2c7640aab76dd 323 PIRSF PIRSF017082 1 323 1.3E-79 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_2c05810 b964eb1e52433b7ee1f2c7640aab76dd 323 SUPERFAMILY SSF53850 96 288 4.56E-9 T 12-10-2018 VAPA_2c05810 b964eb1e52433b7ee1f2c7640aab76dd 323 Gene3D G3DSA:3.40.190.150 28 313 1.4E-108 T 12-10-2018 VAPA_1c11770 362addc37898f58e0bd6b1c8576bf9ab 706 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 74 706 4.4E-104 T 12-10-2018 IPR010105 TonB-dependent siderophore receptor GO:0005506|GO:0015891|GO:0038023 VAPA_1c11770 362addc37898f58e0bd6b1c8576bf9ab 706 Pfam PF07715 TonB-dependent Receptor Plug Domain 73 174 7.7E-20 T 12-10-2018 IPR012910 TonB-dependent receptor, plug domain VAPA_1c11770 362addc37898f58e0bd6b1c8576bf9ab 706 Gene3D G3DSA:2.170.130.10 49 183 3.2E-38 T 12-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily VAPA_1c11770 362addc37898f58e0bd6b1c8576bf9ab 706 SUPERFAMILY SSF56935 27 706 2.75E-131 T 12-10-2018 VAPA_1c11770 362addc37898f58e0bd6b1c8576bf9ab 706 Gene3D G3DSA:2.40.170.20 184 706 1.0E-130 T 12-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily VAPA_1c11770 362addc37898f58e0bd6b1c8576bf9ab 706 Pfam PF00593 TonB dependent receptor 253 705 4.1E-50 T 12-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel VAPA_1c23530 d01f1cb957746b8b4f514f8fbd99ba78 476 SUPERFAMILY SSF55424 353 473 1.56E-42 T 12-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 VAPA_1c23530 d01f1cb957746b8b4f514f8fbd99ba78 476 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 186 204 6.8E-40 T 12-10-2018 VAPA_1c23530 d01f1cb957746b8b4f514f8fbd99ba78 476 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 8 27 6.8E-40 T 12-10-2018 VAPA_1c23530 d01f1cb957746b8b4f514f8fbd99ba78 476 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 274 290 6.8E-40 T 12-10-2018 VAPA_1c23530 d01f1cb957746b8b4f514f8fbd99ba78 476 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 303 325 6.8E-40 T 12-10-2018 VAPA_1c23530 d01f1cb957746b8b4f514f8fbd99ba78 476 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 147 165 6.8E-40 T 12-10-2018 VAPA_1c23530 d01f1cb957746b8b4f514f8fbd99ba78 476 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 338 1.3E-68 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 VAPA_1c23530 d01f1cb957746b8b4f514f8fbd99ba78 476 SUPERFAMILY SSF51905 2 348 2.67E-59 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c23530 d01f1cb957746b8b4f514f8fbd99ba78 476 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 5 474 7.1E-162 T 12-10-2018 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 VAPA_1c23530 d01f1cb957746b8b4f514f8fbd99ba78 476 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 357 466 2.7E-37 T 12-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 VAPA_1c23530 d01f1cb957746b8b4f514f8fbd99ba78 476 Gene3D G3DSA:3.50.50.60 165 287 3.0E-111 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c23530 d01f1cb957746b8b4f514f8fbd99ba78 476 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 46 61 2.0E-76 T 12-10-2018 VAPA_1c23530 d01f1cb957746b8b4f514f8fbd99ba78 476 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 353 374 2.0E-76 T 12-10-2018 VAPA_1c23530 d01f1cb957746b8b4f514f8fbd99ba78 476 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 150 159 2.0E-76 T 12-10-2018 VAPA_1c23530 d01f1cb957746b8b4f514f8fbd99ba78 476 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 275 289 2.0E-76 T 12-10-2018 VAPA_1c23530 d01f1cb957746b8b4f514f8fbd99ba78 476 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 440 460 2.0E-76 T 12-10-2018 VAPA_1c23530 d01f1cb957746b8b4f514f8fbd99ba78 476 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 7 29 2.0E-76 T 12-10-2018 VAPA_1c23530 d01f1cb957746b8b4f514f8fbd99ba78 476 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 318 325 2.0E-76 T 12-10-2018 VAPA_1c23530 d01f1cb957746b8b4f514f8fbd99ba78 476 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 186 211 2.0E-76 T 12-10-2018 VAPA_1c23530 d01f1cb957746b8b4f514f8fbd99ba78 476 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 418 433 2.0E-76 T 12-10-2018 VAPA_1c23530 d01f1cb957746b8b4f514f8fbd99ba78 476 Gene3D G3DSA:3.50.50.60 6 345 3.0E-111 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c23530 d01f1cb957746b8b4f514f8fbd99ba78 476 PIRSF PIRSF000350 1 475 4.1E-84 T 12-10-2018 IPR001100 Pyridine nucleotide-disulphide oxidoreductase, class I GO:0009055|GO:0016491 VAPA_1c23530 d01f1cb957746b8b4f514f8fbd99ba78 476 Gene3D G3DSA:3.30.390.30 356 476 3.1E-46 T 12-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 VAPA_1c54390 0cf9f4e88c6d41687451b3f3e7672843 352 Gene3D G3DSA:3.40.800.20 1 352 1.1E-112 T 12-10-2018 IPR037138 Histone deacetylase domain superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 VAPA_1c54390 0cf9f4e88c6d41687451b3f3e7672843 352 PRINTS PR01270 Histone deacetylase superfamily signature 197 212 1.3E-15 T 12-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 VAPA_1c54390 0cf9f4e88c6d41687451b3f3e7672843 352 PRINTS PR01270 Histone deacetylase superfamily signature 165 188 1.3E-15 T 12-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 VAPA_1c54390 0cf9f4e88c6d41687451b3f3e7672843 352 PRINTS PR01270 Histone deacetylase superfamily signature 283 293 1.3E-15 T 12-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 VAPA_1c54390 0cf9f4e88c6d41687451b3f3e7672843 352 SUPERFAMILY SSF52768 27 348 4.8E-85 T 12-10-2018 IPR023696 Ureohydrolase domain superfamily VAPA_1c54390 0cf9f4e88c6d41687451b3f3e7672843 352 Pfam PF00850 Histone deacetylase domain 33 342 6.8E-67 T 12-10-2018 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 VAPA_1c32980 15c76eaa89ad1aa64d93d879e7676cd2 262 Pfam PF00072 Response regulator receiver domain 49 154 6.5E-16 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_1c32980 15c76eaa89ad1aa64d93d879e7676cd2 262 SMART SM00448 47 160 5.7E-19 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_1c32980 15c76eaa89ad1aa64d93d879e7676cd2 262 SUPERFAMILY SSF52172 46 222 9.32E-24 T 12-10-2018 IPR011006 CheY-like superfamily VAPA_1c32980 15c76eaa89ad1aa64d93d879e7676cd2 262 Gene3D G3DSA:3.40.50.2300 44 147 2.8E-16 T 12-10-2018 VAPA_1c32980 15c76eaa89ad1aa64d93d879e7676cd2 262 ProSitePatterns PS00622 LuxR-type HTH domain signature. 216 243 - T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_1c32980 15c76eaa89ad1aa64d93d879e7676cd2 262 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 232 244 8.1E-13 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_1c32980 15c76eaa89ad1aa64d93d879e7676cd2 262 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 202 216 8.1E-13 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_1c32980 15c76eaa89ad1aa64d93d879e7676cd2 262 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 216 232 8.1E-13 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_1c32980 15c76eaa89ad1aa64d93d879e7676cd2 262 SMART SM00421 199 256 6.9E-24 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_1c32980 15c76eaa89ad1aa64d93d879e7676cd2 262 Gene3D G3DSA:1.10.10.10 148 262 4.6E-31 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c32980 15c76eaa89ad1aa64d93d879e7676cd2 262 Pfam PF00196 Bacterial regulatory proteins, luxR family 201 256 1.4E-20 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_2c05680 c0b122847c75987bc6b39580d00a4758 126 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 13 117 1.6E-8 T 12-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain VAPA_2c05680 c0b122847c75987bc6b39580d00a4758 126 Gene3D G3DSA:3.10.180.10 3 122 1.4E-15 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase VAPA_2c05680 c0b122847c75987bc6b39580d00a4758 126 SUPERFAMILY SSF54593 10 117 1.16E-19 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase VAPA_1c22730 5a808efa5fa07ebd1dfcf92bbcc23562 448 Pfam PF12831 FAD dependent oxidoreductase 18 438 1.5E-114 T 12-10-2018 IPR039649 Digeranylgeranylglycerophospholipid reductase, N-terminal VAPA_1c22730 5a808efa5fa07ebd1dfcf92bbcc23562 448 Gene3D G3DSA:3.50.50.60 2 182 1.0E-15 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c22730 5a808efa5fa07ebd1dfcf92bbcc23562 448 SUPERFAMILY SSF51905 12 420 1.73E-24 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c22730 5a808efa5fa07ebd1dfcf92bbcc23562 448 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 18 40 3.7E-5 T 12-10-2018 VAPA_1c22730 5a808efa5fa07ebd1dfcf92bbcc23562 448 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 404 419 3.7E-5 T 12-10-2018 VAPA_1c29360 0278c556d547d49b82edc611c31d756d 185 Pfam PF10543 ORF6N domain 22 110 1.4E-25 T 12-10-2018 IPR018873 KilA-N, DNA-binding domain VAPA_1c32500 a1fa01aacf5d21e919a08aad4cc3189f 330 PIRSF PIRSF017082 1 330 5.7E-79 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c32500 a1fa01aacf5d21e919a08aad4cc3189f 330 Gene3D G3DSA:3.40.190.150 39 320 2.6E-107 T 12-10-2018 VAPA_1c32500 a1fa01aacf5d21e919a08aad4cc3189f 330 SUPERFAMILY SSF53850 117 293 4.34E-15 T 12-10-2018 VAPA_1c32500 a1fa01aacf5d21e919a08aad4cc3189f 330 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 53 327 7.4E-83 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c32500 a1fa01aacf5d21e919a08aad4cc3189f 330 Gene3D G3DSA:3.40.190.10 132 255 2.6E-107 T 12-10-2018 VAPA_1c37090 69bedb23f6806139af4a1188ed4f6ed5 268 Pfam PF12697 Alpha/beta hydrolase family 6 259 1.5E-13 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 VAPA_1c37090 69bedb23f6806139af4a1188ed4f6ed5 268 SUPERFAMILY SSF53474 3 264 1.66E-30 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c37090 69bedb23f6806139af4a1188ed4f6ed5 268 Gene3D G3DSA:3.40.50.1820 2 267 6.8E-45 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c43390 141c7e8fe5db09d05372f47a9c607830 652 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 598 649 1.7E-10 T 12-10-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain VAPA_1c43390 141c7e8fe5db09d05372f47a9c607830 652 PRINTS PR01005 Flagellar hook-associated protein signature 155 179 1.6E-33 T 12-10-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 VAPA_1c43390 141c7e8fe5db09d05372f47a9c607830 652 PRINTS PR01005 Flagellar hook-associated protein signature 122 142 1.6E-33 T 12-10-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 VAPA_1c43390 141c7e8fe5db09d05372f47a9c607830 652 PRINTS PR01005 Flagellar hook-associated protein signature 259 281 1.6E-33 T 12-10-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 VAPA_1c43390 141c7e8fe5db09d05372f47a9c607830 652 PRINTS PR01005 Flagellar hook-associated protein signature 410 427 1.6E-33 T 12-10-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 VAPA_1c43390 141c7e8fe5db09d05372f47a9c607830 652 PRINTS PR01005 Flagellar hook-associated protein signature 10 33 1.6E-33 T 12-10-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 VAPA_1c43390 141c7e8fe5db09d05372f47a9c607830 652 PRINTS PR01005 Flagellar hook-associated protein signature 48 70 1.6E-33 T 12-10-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 VAPA_1c43390 141c7e8fe5db09d05372f47a9c607830 652 PRINTS PR01005 Flagellar hook-associated protein signature 215 233 1.6E-33 T 12-10-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 VAPA_1c43390 141c7e8fe5db09d05372f47a9c607830 652 SUPERFAMILY SSF64518 466 649 6.8E-24 T 12-10-2018 VAPA_1c43390 141c7e8fe5db09d05372f47a9c607830 652 TIGRFAM TIGR02492 flgK_ends: flagellar hook-associated protein FlgK 2 373 9.2E-81 T 12-10-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 VAPA_1c43390 141c7e8fe5db09d05372f47a9c607830 652 SUPERFAMILY SSF64518 122 452 1.02E-29 T 12-10-2018 VAPA_1c31450 f38cc103b0e3acc0a66b9140b76e7892 316 TIGRFAM TIGR00768 rimK_fam: alpha-L-glutamate ligase, RimK family 4 292 6.9E-45 T 12-10-2018 IPR004666 Ribosomal S6 modification enzyme RimK/Lysine biosynthesis enzyme LysX GO:0006464 Reactome: R-HSA-70614 VAPA_1c31450 f38cc103b0e3acc0a66b9140b76e7892 316 Gene3D G3DSA:3.30.470.80 190 298 7.4E-34 T 12-10-2018 VAPA_1c31450 f38cc103b0e3acc0a66b9140b76e7892 316 Pfam PF08443 RimK-like ATP-grasp domain 102 292 3.5E-18 T 12-10-2018 IPR013651 ATP-grasp fold, RimK-type Reactome: R-HSA-70614 VAPA_1c31450 f38cc103b0e3acc0a66b9140b76e7892 316 Gene3D G3DSA:3.40.50.20 2 116 6.6E-26 T 12-10-2018 VAPA_1c31450 f38cc103b0e3acc0a66b9140b76e7892 316 SUPERFAMILY SSF56059 104 297 1.68E-35 T 12-10-2018 VAPA_2c07950 f20acfb1eab8ac788fe1f22d06f37e0f 149 Pfam PF04120 Low affinity iron permease 5 127 3.1E-49 T 12-10-2018 IPR007251 Low affinity iron permease, Fet4 GO:0055085 VAPA_1c20320 b15efb07da3de381dd7c60fe7c90546d 280 SUPERFAMILY SSF51197 1 280 5.49E-88 T 12-10-2018 VAPA_1c20320 b15efb07da3de381dd7c60fe7c90546d 280 Pfam PF02668 Taurine catabolism dioxygenase TauD, TfdA family 3 272 1.9E-60 T 12-10-2018 IPR003819 TauD/TfdA-like domain GO:0016491|GO:0055114 Reactome: R-HSA-71262 VAPA_1c20320 b15efb07da3de381dd7c60fe7c90546d 280 Gene3D G3DSA:3.60.130.10 1 280 2.4E-83 T 12-10-2018 VAPA_1c05060 8424e69614c2ecd3e0c5755a2947313b 437 Gene3D G3DSA:3.40.50.11280 65 204 6.9E-45 T 12-10-2018 VAPA_1c05060 8424e69614c2ecd3e0c5755a2947313b 437 Pfam PF08886 Glutamate-cysteine ligase 17 426 7.5E-168 T 12-10-2018 IPR011718 Glutamate--cysteine ligase GshA VAPA_1c05060 8424e69614c2ecd3e0c5755a2947313b 437 TIGRFAM TIGR02049 gshA_ferroox: glutamate--cysteine ligase 17 429 4.2E-154 T 12-10-2018 IPR011718 Glutamate--cysteine ligase GshA VAPA_1c09510 ac57125f2cb96ac176338bc416961725 218 SUPERFAMILY SSF52833 9 214 6.94E-37 T 12-10-2018 IPR036249 Thioredoxin-like superfamily VAPA_1c09510 ac57125f2cb96ac176338bc416961725 218 PIRSF PIRSF006386 6 217 1.2E-49 T 12-10-2018 IPR014440 HCCA isomerase/glutathione S-transferase kappa Reactome: R-HSA-156590|Reactome: R-HSA-9033241 VAPA_1c09510 ac57125f2cb96ac176338bc416961725 218 Pfam PF01323 DSBA-like thioredoxin domain 11 209 2.3E-30 T 12-10-2018 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590|Reactome: R-HSA-9033241 VAPA_1c09510 ac57125f2cb96ac176338bc416961725 218 Gene3D G3DSA:3.40.30.10 9 217 8.8E-51 T 12-10-2018 VAPA_1c23630 7fba9c4c48c955b2a15f67e14c00f851 141 Gene3D G3DSA:3.30.70.141 1 141 2.0E-60 T 12-10-2018 IPR036850 Nucleoside diphosphate kinase-like domain superfamily KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 VAPA_1c23630 7fba9c4c48c955b2a15f67e14c00f851 141 ProSitePatterns PS00469 Nucleoside diphosphate kinases active site. 114 122 - T 12-10-2018 IPR023005 Nucleoside diphosphate kinase, active site KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 VAPA_1c23630 7fba9c4c48c955b2a15f67e14c00f851 141 SMART SM00562 3 140 8.8E-85 T 12-10-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 VAPA_1c23630 7fba9c4c48c955b2a15f67e14c00f851 141 SUPERFAMILY SSF54919 1 138 6.42E-58 T 12-10-2018 IPR036850 Nucleoside diphosphate kinase-like domain superfamily KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 VAPA_1c23630 7fba9c4c48c955b2a15f67e14c00f851 141 PRINTS PR01243 Nucleoside diphosphate kinase signature 50 69 9.3E-41 T 12-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 VAPA_1c23630 7fba9c4c48c955b2a15f67e14c00f851 141 PRINTS PR01243 Nucleoside diphosphate kinase signature 6 28 9.3E-41 T 12-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 VAPA_1c23630 7fba9c4c48c955b2a15f67e14c00f851 141 PRINTS PR01243 Nucleoside diphosphate kinase signature 91 107 9.3E-41 T 12-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 VAPA_1c23630 7fba9c4c48c955b2a15f67e14c00f851 141 PRINTS PR01243 Nucleoside diphosphate kinase signature 114 133 9.3E-41 T 12-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 VAPA_1c23630 7fba9c4c48c955b2a15f67e14c00f851 141 PRINTS PR01243 Nucleoside diphosphate kinase signature 70 87 9.3E-41 T 12-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 VAPA_1c23630 7fba9c4c48c955b2a15f67e14c00f851 141 Hamap MF_00451 Nucleoside diphosphate kinase [ndk]. 3 138 35.798 T 12-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 VAPA_1c23630 7fba9c4c48c955b2a15f67e14c00f851 141 Pfam PF00334 Nucleoside diphosphate kinase 4 134 1.9E-56 T 12-10-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 VAPA_1c33440 8e9b3a1e4c97a670e7589583a56d67cc 218 Gene3D G3DSA:3.30.1330.60 42 216 7.4E-37 T 12-10-2018 IPR036737 OmpA-like domain superfamily VAPA_1c33440 8e9b3a1e4c97a670e7589583a56d67cc 218 SUPERFAMILY SSF103088 80 203 2.88E-26 T 12-10-2018 IPR036737 OmpA-like domain superfamily VAPA_1c33440 8e9b3a1e4c97a670e7589583a56d67cc 218 Pfam PF00691 OmpA family 92 199 1.4E-18 T 12-10-2018 IPR006665 OmpA-like domain VAPA_1c34920 c8d2b9d9d67a518c52238c6bb2a4e0f5 557 Gene3D G3DSA:3.50.50.60 39 406 1.6E-130 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c34920 c8d2b9d9d67a518c52238c6bb2a4e0f5 557 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 387 399 8.3E-25 T 12-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 VAPA_1c34920 c8d2b9d9d67a518c52238c6bb2a4e0f5 557 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 51 61 8.3E-25 T 12-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 VAPA_1c34920 c8d2b9d9d67a518c52238c6bb2a4e0f5 557 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 38 50 8.3E-25 T 12-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 VAPA_1c34920 c8d2b9d9d67a518c52238c6bb2a4e0f5 557 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 67 79 8.3E-25 T 12-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 VAPA_1c34920 c8d2b9d9d67a518c52238c6bb2a4e0f5 557 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 112 124 8.3E-25 T 12-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 VAPA_1c34920 c8d2b9d9d67a518c52238c6bb2a4e0f5 557 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 355 361 8.3E-25 T 12-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 VAPA_1c34920 c8d2b9d9d67a518c52238c6bb2a4e0f5 557 Pfam PF01266 FAD dependent oxidoreductase 39 397 2.6E-57 T 12-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 VAPA_1c34920 c8d2b9d9d67a518c52238c6bb2a4e0f5 557 Gene3D G3DSA:1.10.8.870 445 513 5.8E-21 T 12-10-2018 IPR038299 Alpha-glycerophosphate oxidase, C-terminal domain superfamily KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 VAPA_1c34920 c8d2b9d9d67a518c52238c6bb2a4e0f5 557 Pfam PF16901 C-terminal domain of alpha-glycerophosphate oxidase 426 534 4.0E-9 T 12-10-2018 IPR031656 Alpha-glycerophosphate oxidase, C-terminal KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 VAPA_1c34920 c8d2b9d9d67a518c52238c6bb2a4e0f5 557 SUPERFAMILY SSF51905 36 334 1.68E-37 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c34920 c8d2b9d9d67a518c52238c6bb2a4e0f5 557 Gene3D G3DSA:3.30.9.10 116 362 1.6E-130 T 12-10-2018 VAPA_1c34920 c8d2b9d9d67a518c52238c6bb2a4e0f5 557 ProSitePatterns PS00977 FAD-dependent glycerol-3-phosphate dehydrogenase signature 1. 43 60 - T 12-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 VAPA_2c09410 ebb0c3e05e4bb21d607af22885074583 223 Pfam PF00873 AcrB/AcrD/AcrF family 1 189 1.2E-70 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 VAPA_2c09410 ebb0c3e05e4bb21d607af22885074583 223 Gene3D G3DSA:3.30.70.1440 2 29 8.5E-62 T 12-10-2018 VAPA_2c09410 ebb0c3e05e4bb21d607af22885074583 223 Gene3D G3DSA:1.20.1640.10 30 186 8.5E-62 T 12-10-2018 VAPA_2c09410 ebb0c3e05e4bb21d607af22885074583 223 SUPERFAMILY SSF82866 2 188 2.09E-44 T 12-10-2018 VAPA_2c10510 7e23abe4c769899b3bd701a118d37250 273 Pfam PF00561 alpha/beta hydrolase fold 22 253 1.8E-23 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 VAPA_2c10510 7e23abe4c769899b3bd701a118d37250 273 SUPERFAMILY SSF53474 2 272 4.71E-67 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_2c10510 7e23abe4c769899b3bd701a118d37250 273 PRINTS PR00111 Alpha/beta hydrolase fold signature 91 104 7.2E-11 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 VAPA_2c10510 7e23abe4c769899b3bd701a118d37250 273 PRINTS PR00111 Alpha/beta hydrolase fold signature 47 62 7.2E-11 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 VAPA_2c10510 7e23abe4c769899b3bd701a118d37250 273 PRINTS PR00111 Alpha/beta hydrolase fold signature 216 230 7.2E-11 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 VAPA_2c10510 7e23abe4c769899b3bd701a118d37250 273 Gene3D G3DSA:3.40.50.1820 1 272 4.9E-85 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_2c01400 8c03c55c30fe07754c4b540f2416ce13 454 SUPERFAMILY SSF142764 7 450 3.53E-93 T 12-10-2018 VAPA_2c01400 8c03c55c30fe07754c4b540f2416ce13 454 Gene3D G3DSA:3.40.50.10840 5 258 1.3E-66 T 12-10-2018 IPR037051 Four-carbon acid sugar kinase, N-terminal domain superfamily VAPA_2c01400 8c03c55c30fe07754c4b540f2416ce13 454 Gene3D G3DSA:3.40.980.20 263 452 2.7E-47 T 12-10-2018 VAPA_2c01400 8c03c55c30fe07754c4b540f2416ce13 454 Pfam PF07005 Putative sugar-binding N-terminal domain 7 246 3.2E-48 T 12-10-2018 IPR010737 Four-carbon acid sugar kinase, N-terminal domain VAPA_2c01400 8c03c55c30fe07754c4b540f2416ce13 454 Pfam PF17042 Putative nucleotide-binding of sugar-metabolising enzyme 273 445 4.8E-41 T 12-10-2018 IPR031475 Four-carbon acid sugar kinase, C-terminal domain VAPA_1c26400 94700dd8c650424d70fb32118446f793 301 Pfam PF00106 short chain dehydrogenase 8 207 5.7E-37 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c26400 94700dd8c650424d70fb32118446f793 301 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 162 181 2.9E-5 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c26400 94700dd8c650424d70fb32118446f793 301 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 142 150 2.9E-5 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c26400 94700dd8c650424d70fb32118446f793 301 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 2.9E-5 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c26400 94700dd8c650424d70fb32118446f793 301 SUPERFAMILY SSF51735 1 257 3.45E-55 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c26400 94700dd8c650424d70fb32118446f793 301 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 185 202 3.2E-13 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c26400 94700dd8c650424d70fb32118446f793 301 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 136 152 3.2E-13 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c26400 94700dd8c650424d70fb32118446f793 301 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 3.2E-13 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c26400 94700dd8c650424d70fb32118446f793 301 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 3.2E-13 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c26400 94700dd8c650424d70fb32118446f793 301 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 162 181 3.2E-13 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c26400 94700dd8c650424d70fb32118446f793 301 Gene3D G3DSA:3.40.50.720 1 294 5.2E-73 T 12-10-2018 VAPA_1c38110 03a26e8f700adad6ae256f69f09334e1 461 Pfam PF13416 Bacterial extracellular solute-binding protein 49 398 1.1E-36 T 12-10-2018 IPR006059 Bacterial extracellular solute-binding protein VAPA_1c38110 03a26e8f700adad6ae256f69f09334e1 461 Gene3D G3DSA:3.40.190.10 26 461 1.6E-51 T 12-10-2018 VAPA_1c38110 03a26e8f700adad6ae256f69f09334e1 461 SUPERFAMILY SSF53850 26 459 1.9E-45 T 12-10-2018 VAPA_1c42590 beeeb3d96880b6aeee685bc9200f25a2 481 Gene3D G3DSA:2.30.42.10 101 188 1.0E-90 T 12-10-2018 VAPA_1c42590 beeeb3d96880b6aeee685bc9200f25a2 481 Gene3D G3DSA:3.90.226.10 189 378 1.0E-90 T 12-10-2018 VAPA_1c42590 beeeb3d96880b6aeee685bc9200f25a2 481 Gene3D G3DSA:3.30.750.44 52 356 1.0E-90 T 12-10-2018 VAPA_1c42590 beeeb3d96880b6aeee685bc9200f25a2 481 SMART SM00245 174 381 9.9E-61 T 12-10-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 VAPA_1c42590 beeeb3d96880b6aeee685bc9200f25a2 481 SUPERFAMILY SSF52096 39 385 4.64E-74 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily VAPA_1c42590 beeeb3d96880b6aeee685bc9200f25a2 481 SUPERFAMILY SSF50156 94 184 5.11E-20 T 12-10-2018 IPR036034 PDZ superfamily GO:0005515 VAPA_1c42590 beeeb3d96880b6aeee685bc9200f25a2 481 SMART SM00228 101 172 4.1E-14 T 12-10-2018 IPR001478 PDZ domain GO:0005515 VAPA_1c42590 beeeb3d96880b6aeee685bc9200f25a2 481 TIGRFAM TIGR00225 prc: C-terminal processing peptidase 53 385 3.0E-97 T 12-10-2018 IPR004447 C-terminal-processing peptidase S41A GO:0006508|GO:0008236 VAPA_1c42590 beeeb3d96880b6aeee685bc9200f25a2 481 Pfam PF03572 Peptidase family S41 200 378 3.7E-50 T 12-10-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 VAPA_1c42590 beeeb3d96880b6aeee685bc9200f25a2 481 Pfam PF13180 PDZ domain 103 180 1.3E-13 T 12-10-2018 IPR001478 PDZ domain GO:0005515 VAPA_1c22820 11faf5131d571755d5e6966fa3763fd5 264 Gene3D G3DSA:3.90.850.10 1 262 1.5E-84 T 12-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 VAPA_1c22820 11faf5131d571755d5e6966fa3763fd5 264 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 79 258 9.9E-15 T 12-10-2018 IPR011234 Fumarylacetoacetase-like, C-terminal GO:0003824 VAPA_1c22820 11faf5131d571755d5e6966fa3763fd5 264 SUPERFAMILY SSF56529 1 259 1.28E-78 T 12-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 VAPA_2c04090 a01c2f87c345ec3583856be1ce94190e 448 Pfam PF08521 Two-component sensor kinase N-terminal 20 150 6.7E-12 T 12-10-2018 IPR013727 Two-component sensor kinase, N-terminal VAPA_2c04090 a01c2f87c345ec3583856be1ce94190e 448 SUPERFAMILY SSF47384 213 295 1.33E-17 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 VAPA_2c04090 a01c2f87c345ec3583856be1ce94190e 448 SUPERFAMILY SSF55874 284 432 1.13E-27 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_2c04090 a01c2f87c345ec3583856be1ce94190e 448 SMART SM00387 339 448 5.4E-14 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase VAPA_2c04090 a01c2f87c345ec3583856be1ce94190e 448 Gene3D G3DSA:3.30.565.10 297 444 7.3E-26 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_2c04090 a01c2f87c345ec3583856be1ce94190e 448 SMART SM00388 230 295 1.2E-17 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 VAPA_2c04090 a01c2f87c345ec3583856be1ce94190e 448 Pfam PF00512 His Kinase A (phospho-acceptor) domain 231 295 6.2E-16 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 VAPA_2c04090 a01c2f87c345ec3583856be1ce94190e 448 PRINTS PR00344 Bacterial sensor protein C-terminal signature 376 390 9.6E-5 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_2c04090 a01c2f87c345ec3583856be1ce94190e 448 PRINTS PR00344 Bacterial sensor protein C-terminal signature 408 426 9.6E-5 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_2c04090 a01c2f87c345ec3583856be1ce94190e 448 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 340 430 2.4E-12 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase VAPA_2c04090 a01c2f87c345ec3583856be1ce94190e 448 Gene3D G3DSA:1.10.287.130 181 295 2.2E-19 T 12-10-2018 VAPA_1c19530 14b7474a6c7e3f101b7b706c76bb60cb 259 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_1c19530 14b7474a6c7e3f101b7b706c76bb60cb 259 Gene3D G3DSA:3.40.50.300 4 230 8.6E-61 T 12-10-2018 VAPA_1c19530 14b7474a6c7e3f101b7b706c76bb60cb 259 Pfam PF00005 ABC transporter 26 165 3.5E-29 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c19530 14b7474a6c7e3f101b7b706c76bb60cb 259 SUPERFAMILY SSF52540 6 233 1.24E-63 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c19530 14b7474a6c7e3f101b7b706c76bb60cb 259 SMART SM00382 35 216 8.7E-16 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c48750 913f7c354e2436e5f25f02658fe38383 262 Gene3D G3DSA:3.90.226.10 1 202 1.8E-59 T 12-10-2018 VAPA_1c48750 913f7c354e2436e5f25f02658fe38383 262 SUPERFAMILY SSF52096 2 261 3.15E-70 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily VAPA_1c48750 913f7c354e2436e5f25f02658fe38383 262 Gene3D G3DSA:1.10.12.10 204 262 3.2E-23 T 12-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal VAPA_1c48750 913f7c354e2436e5f25f02658fe38383 262 Pfam PF00378 Enoyl-CoA hydratase/isomerase 9 260 7.1E-49 T 12-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 VAPA_1c11470 0d791e6bbefb8f8aa7f2f18206956b5c 356 Gene3D G3DSA:3.40.50.300 1 332 3.0E-100 T 12-10-2018 VAPA_1c11470 0d791e6bbefb8f8aa7f2f18206956b5c 356 ProSitePatterns PS00211 ABC transporters family signature. 154 168 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_1c11470 0d791e6bbefb8f8aa7f2f18206956b5c 356 SUPERFAMILY SSF52540 3 252 3.88E-65 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c11470 0d791e6bbefb8f8aa7f2f18206956b5c 356 Pfam PF00005 ABC transporter 23 181 6.2E-28 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c11470 0d791e6bbefb8f8aa7f2f18206956b5c 356 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 234 297 1.7E-17 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 VAPA_1c11470 0d791e6bbefb8f8aa7f2f18206956b5c 356 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 232 316 3.1E-23 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 VAPA_1c11470 0d791e6bbefb8f8aa7f2f18206956b5c 356 SMART SM00382 32 239 1.1E-14 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c41800 7c96f9c513e1d3fb4cedcdb496b21cef 156 Gene3D G3DSA:2.40.10.330 80 141 7.0E-31 T 12-10-2018 VAPA_1c41800 7c96f9c513e1d3fb4cedcdb496b21cef 156 Gene3D G3DSA:3.10.50.40 23 153 7.0E-31 T 12-10-2018 VAPA_1c41800 7c96f9c513e1d3fb4cedcdb496b21cef 156 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 14 84 8.1E-8 T 12-10-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain VAPA_1c41800 7c96f9c513e1d3fb4cedcdb496b21cef 156 SUPERFAMILY SSF54534 14 155 3.93E-26 T 12-10-2018 VAPA_1c14400 5d04b490faad1c7b7587e1cdaceecec7 222 SUPERFAMILY SSF116726 136 219 7.32E-16 T 12-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 VAPA_1c14400 5d04b490faad1c7b7587e1cdaceecec7 222 Gene3D G3DSA:3.40.50.720 4 142 3.1E-33 T 12-10-2018 VAPA_1c14400 5d04b490faad1c7b7587e1cdaceecec7 222 Pfam PF02254 TrkA-N domain 11 126 2.0E-26 T 12-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 VAPA_1c14400 5d04b490faad1c7b7587e1cdaceecec7 222 Gene3D G3DSA:3.30.70.1450 143 220 5.9E-19 T 12-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 VAPA_1c14400 5d04b490faad1c7b7587e1cdaceecec7 222 SUPERFAMILY SSF51735 10 139 2.18E-34 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c14400 5d04b490faad1c7b7587e1cdaceecec7 222 Pfam PF02080 TrkA-C domain 158 220 3.6E-13 T 12-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 VAPA_1c26450 59c6cb278a7a7bb94b3e9838c3c34cb3 320 Gene3D G3DSA:3.40.190.10 167 268 5.4E-64 T 12-10-2018 VAPA_1c26450 59c6cb278a7a7bb94b3e9838c3c34cb3 320 SUPERFAMILY SSF46785 11 116 1.27E-21 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c26450 59c6cb278a7a7bb94b3e9838c3c34cb3 320 Gene3D G3DSA:1.10.10.10 8 92 9.0E-25 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c26450 59c6cb278a7a7bb94b3e9838c3c34cb3 320 Pfam PF03466 LysR substrate binding domain 92 295 6.5E-39 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_1c26450 59c6cb278a7a7bb94b3e9838c3c34cb3 320 SUPERFAMILY SSF53850 94 297 1.99E-41 T 12-10-2018 VAPA_1c26450 59c6cb278a7a7bb94b3e9838c3c34cb3 320 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 12 67 3.4E-19 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c26450 59c6cb278a7a7bb94b3e9838c3c34cb3 320 Gene3D G3DSA:3.40.190.10 95 295 5.4E-64 T 12-10-2018 VAPA_2c09860 f7c06dfbd0dfcbf33c7cde33861b7032 289 Pfam PF05368 NmrA-like family 3 221 4.2E-31 T 12-10-2018 IPR008030 NmrA-like domain Reactome: R-HSA-70635 VAPA_2c09860 f7c06dfbd0dfcbf33c7cde33861b7032 289 Gene3D G3DSA:3.90.25.10 134 272 9.0E-58 T 12-10-2018 VAPA_2c09860 f7c06dfbd0dfcbf33c7cde33861b7032 289 SUPERFAMILY SSF51735 3 259 2.01E-56 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_2c09860 f7c06dfbd0dfcbf33c7cde33861b7032 289 Gene3D G3DSA:3.40.50.720 4 271 9.0E-58 T 12-10-2018 VAPA_2c11440 515c06c4dc2dfa07f3fd26f7a5c5a866 300 SUPERFAMILY SSF46689 195 245 8.21E-9 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 VAPA_2c11440 515c06c4dc2dfa07f3fd26f7a5c5a866 300 Pfam PF12852 Cupin 3 179 7.8E-32 T 12-10-2018 IPR032783 AraC-type transcription regulator, ligand-binding domain VAPA_2c11440 515c06c4dc2dfa07f3fd26f7a5c5a866 300 SUPERFAMILY SSF46689 248 297 6.67E-12 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 VAPA_2c11440 515c06c4dc2dfa07f3fd26f7a5c5a866 300 Pfam PF12833 Helix-turn-helix domain 218 296 2.6E-18 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 VAPA_2c11440 515c06c4dc2dfa07f3fd26f7a5c5a866 300 Gene3D G3DSA:1.10.10.60 197 299 3.6E-23 T 12-10-2018 VAPA_2c11440 515c06c4dc2dfa07f3fd26f7a5c5a866 300 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 249 291 - T 12-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 VAPA_2c11440 515c06c4dc2dfa07f3fd26f7a5c5a866 300 SMART SM00342 212 295 1.1E-27 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 VAPA_2c02380 0154dc56a3ded18e6517b5cb83119bc5 328 PIRSF PIRSF017082 1 327 4.7E-61 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_2c02380 0154dc56a3ded18e6517b5cb83119bc5 328 SUPERFAMILY SSF53850 118 291 2.99E-12 T 12-10-2018 VAPA_2c02380 0154dc56a3ded18e6517b5cb83119bc5 328 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 55 324 1.6E-71 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_2c02380 0154dc56a3ded18e6517b5cb83119bc5 328 Gene3D G3DSA:3.40.190.150 35 318 4.2E-90 T 12-10-2018 VAPA_2c02380 0154dc56a3ded18e6517b5cb83119bc5 328 Gene3D G3DSA:3.40.190.10 133 253 4.2E-90 T 12-10-2018 VAPA_1c27070 7518f9fdf62eaec543a3d12b7717a2fc 149 Gene3D G3DSA:2.102.10.10 17 129 3.2E-24 T 12-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 VAPA_1c27070 7518f9fdf62eaec543a3d12b7717a2fc 149 TIGRFAM TIGR02378 nirD_assim_sml: nitrite reductase [NAD(P)H], small subunit 21 118 3.5E-24 T 12-10-2018 IPR012748 Nitrite reductase [NAD(P)H] small subunit, NirD GO:0008942|GO:0042128|GO:0055114 VAPA_1c27070 7518f9fdf62eaec543a3d12b7717a2fc 149 Pfam PF00355 Rieske [2Fe-2S] domain 21 107 4.1E-14 T 12-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 VAPA_1c27070 7518f9fdf62eaec543a3d12b7717a2fc 149 SUPERFAMILY SSF50022 19 124 9.43E-32 T 12-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 VAPA_1c18730 c128ba3c8428852d57f06b67e8e3f849 361 SUPERFAMILY SSF53659 2 361 3.07E-111 T 12-10-2018 VAPA_1c18730 c128ba3c8428852d57f06b67e8e3f849 361 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 248 267 - T 12-10-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 VAPA_1c18730 c128ba3c8428852d57f06b67e8e3f849 361 TIGRFAM TIGR02089 TTC: tartrate dehydrogenase 1 361 3.8E-162 T 12-10-2018 IPR011829 Tartrate dehydrogenase GO:0016616|GO:0051287|GO:0055114 KEGG: 00630+1.1.1.93|KEGG: 00650+1.1.1.83 VAPA_1c18730 c128ba3c8428852d57f06b67e8e3f849 361 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 6 357 2.8E-83 T 12-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 VAPA_1c18730 c128ba3c8428852d57f06b67e8e3f849 361 SMART SM01329 5 357 8.0E-168 T 12-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 VAPA_1c18730 c128ba3c8428852d57f06b67e8e3f849 361 Gene3D G3DSA:3.40.718.10 1 361 3.1E-131 T 12-10-2018 VAPA_1c28430 487df743c740384c186df5c0c2aa7e94 274 TIGRFAM TIGR00965 dapD: 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase 4 273 1.9E-130 T 12-10-2018 IPR005664 Tetrahydrodipicolinate N-succinyltransferase, transferase hexapeptide repeat family GO:0008666|GO:0009089 KEGG: 00300+2.3.1.117 VAPA_1c28430 487df743c740384c186df5c0c2aa7e94 274 Hamap MF_00811 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase [dapD]. 2 274 54.919 T 12-10-2018 IPR005664 Tetrahydrodipicolinate N-succinyltransferase, transferase hexapeptide repeat family GO:0008666|GO:0009089 KEGG: 00300+2.3.1.117 VAPA_1c28430 487df743c740384c186df5c0c2aa7e94 274 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 134 168 1.7E-4 T 12-10-2018 IPR001451 Hexapeptide repeat VAPA_1c28430 487df743c740384c186df5c0c2aa7e94 274 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 136 164 - T 12-10-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 VAPA_1c28430 487df743c740384c186df5c0c2aa7e94 274 Gene3D G3DSA:2.160.10.10 89 259 2.8E-54 T 12-10-2018 VAPA_1c28430 487df743c740384c186df5c0c2aa7e94 274 SUPERFAMILY SSF51161 3 258 2.08E-71 T 12-10-2018 IPR011004 Trimeric LpxA-like superfamily VAPA_1c28430 487df743c740384c186df5c0c2aa7e94 274 Pfam PF14805 Tetrahydrodipicolinate N-succinyltransferase N-terminal 4 71 2.1E-25 T 12-10-2018 IPR023180 Tetrahydrodipicolinate-N-succinyltransferase, chain A, domain 1 KEGG: 00300+2.3.1.117 VAPA_1c28430 487df743c740384c186df5c0c2aa7e94 274 Gene3D G3DSA:1.10.166.10 2 72 6.5E-30 T 12-10-2018 IPR037133 Tetrahydrodipicolinate-N-succinyltransferase, N-terminal domain superfamily KEGG: 00300+2.3.1.117 VAPA_1c28430 487df743c740384c186df5c0c2aa7e94 274 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 177 211 6.3E-13 T 12-10-2018 IPR001451 Hexapeptide repeat VAPA_1c12280 f492f9f42773c22373df86afb1e491eb 218 SUPERFAMILY SSF52317 6 216 4.01E-52 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like VAPA_1c12280 f492f9f42773c22373df86afb1e491eb 218 Gene3D G3DSA:3.40.50.880 3 217 3.0E-70 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like VAPA_1c12280 f492f9f42773c22373df86afb1e491eb 218 Hamap MF_00278 Imidazole glycerol phosphate synthase subunit HisH [hisH]. 7 216 34.359 T 12-10-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 VAPA_1c12280 f492f9f42773c22373df86afb1e491eb 218 PIRSF PIRSF000495 6 218 3.8E-66 T 12-10-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 VAPA_1c12280 f492f9f42773c22373df86afb1e491eb 218 TIGRFAM TIGR01855 IMP_synth_hisH: imidazole glycerol phosphate synthase, glutamine amidotransferase subunit 8 215 3.2E-62 T 12-10-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 VAPA_1c12280 f492f9f42773c22373df86afb1e491eb 218 Pfam PF00117 Glutamine amidotransferase class-I 10 213 4.4E-15 T 12-10-2018 IPR017926 Glutamine amidotransferase VAPA_1c31700 54f00275a1b582de5ed0f05e5e591ac7 162 Gene3D G3DSA:3.30.700.10 27 160 7.0E-26 T 12-10-2018 VAPA_1c31700 54f00275a1b582de5ed0f05e5e591ac7 162 Pfam PF07963 Prokaryotic N-terminal methylation motif 22 47 1.1E-9 T 12-10-2018 IPR012902 Prokaryotic N-terminal methylation site VAPA_1c31700 54f00275a1b582de5ed0f05e5e591ac7 162 Pfam PF16732 Type IV minor pilin ComP, DNA uptake sequence receptor 48 136 4.8E-25 T 12-10-2018 IPR031982 Type IV minor pilin ComP VAPA_1c31700 54f00275a1b582de5ed0f05e5e591ac7 162 SUPERFAMILY SSF54523 27 143 5.76E-26 T 12-10-2018 VAPA_1c31700 54f00275a1b582de5ed0f05e5e591ac7 162 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 25 45 - T 12-10-2018 IPR012902 Prokaryotic N-terminal methylation site VAPA_1c31700 54f00275a1b582de5ed0f05e5e591ac7 162 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 25 47 2.3E-9 T 12-10-2018 IPR012902 Prokaryotic N-terminal methylation site VAPA_1c15420 c290e1d70e7f9202dc77d10f122efac9 217 TIGRFAM TIGR03035 trp_arylform: arylformamidase 9 215 2.0E-87 T 12-10-2018 IPR017484 Kynurenine formamidase, bacteria GO:0004328|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 VAPA_1c15420 c290e1d70e7f9202dc77d10f122efac9 217 Gene3D G3DSA:3.50.30.50 5 217 3.4E-63 T 12-10-2018 IPR037175 Kynurenine formamidase superfamily GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 VAPA_1c15420 c290e1d70e7f9202dc77d10f122efac9 217 Pfam PF04199 Putative cyclase 12 158 1.2E-14 T 12-10-2018 IPR007325 Kynurenine formamidase/cyclase-like GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 VAPA_1c15420 c290e1d70e7f9202dc77d10f122efac9 217 Hamap MF_01969 Kynurenine formamidase [kynB]. 9 215 42.18 T 12-10-2018 IPR017484 Kynurenine formamidase, bacteria GO:0004328|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 VAPA_1c15420 c290e1d70e7f9202dc77d10f122efac9 217 SUPERFAMILY SSF102198 8 213 1.57E-53 T 12-10-2018 IPR037175 Kynurenine formamidase superfamily GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 VAPA_1c40750 c7d33732a3a0c5303ad8499cfbae0f11 251 Pfam PF07729 FCD domain 102 227 2.8E-19 T 12-10-2018 IPR011711 GntR, C-terminal VAPA_1c40750 c7d33732a3a0c5303ad8499cfbae0f11 251 Pfam PF00392 Bacterial regulatory proteins, gntR family 32 92 3.7E-12 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_1c40750 c7d33732a3a0c5303ad8499cfbae0f11 251 Gene3D G3DSA:1.10.10.10 15 92 8.9E-16 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c40750 c7d33732a3a0c5303ad8499cfbae0f11 251 SUPERFAMILY SSF46785 27 110 4.44E-15 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c40750 c7d33732a3a0c5303ad8499cfbae0f11 251 Gene3D G3DSA:1.20.120.530 95 235 5.9E-22 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal VAPA_1c40750 c7d33732a3a0c5303ad8499cfbae0f11 251 SMART SM00345 34 92 1.7E-9 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_1c40750 c7d33732a3a0c5303ad8499cfbae0f11 251 SMART SM00895 102 227 5.7E-15 T 12-10-2018 IPR011711 GntR, C-terminal VAPA_1c40750 c7d33732a3a0c5303ad8499cfbae0f11 251 SUPERFAMILY SSF48008 98 232 1.91E-23 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal VAPA_1c14750 cbc3df57cb628060dcde84296fb1b8b4 347 Gene3D G3DSA:3.40.1750.20 199 265 7.1E-65 T 12-10-2018 VAPA_1c14750 cbc3df57cb628060dcde84296fb1b8b4 347 Pfam PF01343 Peptidase family S49 160 310 2.8E-36 T 12-10-2018 IPR002142 Peptidase S49 GO:0006508|GO:0008233 VAPA_1c14750 cbc3df57cb628060dcde84296fb1b8b4 347 SUPERFAMILY SSF52096 75 297 6.46E-45 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily VAPA_1c14750 cbc3df57cb628060dcde84296fb1b8b4 347 Gene3D G3DSA:3.90.226.10 99 299 7.1E-65 T 12-10-2018 VAPA_1c44580 e2459061aec2a0d5dfcc40669fcd5c77 98 Gene3D G3DSA:2.40.10.180 3 97 7.3E-6 T 12-10-2018 VAPA_1c12810 6e6c6508d8f90461f985f04f5f741711 489 Gene3D G3DSA:3.30.1490.130 293 349 2.5E-160 T 12-10-2018 IPR023100 D-aminoacylase, insert domain superfamily GO:0016811 VAPA_1c12810 6e6c6508d8f90461f985f04f5f741711 489 SUPERFAMILY SSF51556 68 424 1.77E-82 T 12-10-2018 IPR032466 Metal-dependent hydrolase VAPA_1c12810 6e6c6508d8f90461f985f04f5f741711 489 Gene3D G3DSA:2.30.40.10 9 438 2.5E-160 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 VAPA_1c12810 6e6c6508d8f90461f985f04f5f741711 489 SUPERFAMILY SSF51338 8 473 1.25E-13 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 VAPA_1c12810 6e6c6508d8f90461f985f04f5f741711 489 Gene3D G3DSA:3.20.20.140 67 424 2.5E-160 T 12-10-2018 VAPA_1c12810 6e6c6508d8f90461f985f04f5f741711 489 Pfam PF07969 Amidohydrolase family 356 469 6.4E-14 T 12-10-2018 IPR013108 Amidohydrolase 3 VAPA_1c12810 6e6c6508d8f90461f985f04f5f741711 489 Pfam PF07969 Amidohydrolase family 56 226 2.9E-16 T 12-10-2018 IPR013108 Amidohydrolase 3 VAPA_2c10170 e853a650d379f8a362a68c471112afd4 238 Pfam PF00072 Response regulator receiver domain 15 125 1.9E-21 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_2c10170 e853a650d379f8a362a68c471112afd4 238 Gene3D G3DSA:3.40.50.2300 3 138 5.8E-30 T 12-10-2018 VAPA_2c10170 e853a650d379f8a362a68c471112afd4 238 SUPERFAMILY SSF52172 11 137 1.85E-32 T 12-10-2018 IPR011006 CheY-like superfamily VAPA_2c10170 e853a650d379f8a362a68c471112afd4 238 SMART SM00862 160 234 8.3E-15 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 VAPA_2c10170 e853a650d379f8a362a68c471112afd4 238 SUPERFAMILY SSF46894 134 234 1.26E-17 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 VAPA_2c10170 e853a650d379f8a362a68c471112afd4 238 Pfam PF00486 Transcriptional regulatory protein, C terminal 161 234 1.4E-13 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 VAPA_2c10170 e853a650d379f8a362a68c471112afd4 238 SMART SM00448 13 125 1.1E-31 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_2c10170 e853a650d379f8a362a68c471112afd4 238 Gene3D G3DSA:1.10.10.10 141 237 3.9E-20 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c01530 841b817466f8325a5854996cb5bb663c 267 SMART SM00382 52 244 2.0E-5 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c01530 841b817466f8325a5854996cb5bb663c 267 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 244 266 1.9E-4 T 12-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal VAPA_1c01530 841b817466f8325a5854996cb5bb663c 267 Pfam PF00005 ABC transporter 44 197 2.7E-29 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c01530 841b817466f8325a5854996cb5bb663c 267 Gene3D G3DSA:3.40.50.300 14 264 5.0E-61 T 12-10-2018 VAPA_1c01530 841b817466f8325a5854996cb5bb663c 267 SUPERFAMILY SSF52540 26 265 4.47E-63 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c01530 841b817466f8325a5854996cb5bb663c 267 TIGRFAM TIGR03411 urea_trans_UrtD: urea ABC transporter, ATP-binding protein UrtD 27 267 9.2E-110 T 12-10-2018 IPR017781 ABC transporter, urea, ATP-binding protein, UrtD VAPA_1c40930 8a5c345408b89e253c45f4aab80cb71b 597 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 4 172 1.6E-52 T 12-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 VAPA_1c40930 8a5c345408b89e253c45f4aab80cb71b 597 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 193 327 4.8E-36 T 12-10-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 VAPA_1c40930 8a5c345408b89e253c45f4aab80cb71b 597 Gene3D G3DSA:3.40.50.1220 192 358 1.4E-48 T 12-10-2018 VAPA_1c40930 8a5c345408b89e253c45f4aab80cb71b 597 Gene3D G3DSA:3.40.50.970 359 586 9.0E-62 T 12-10-2018 VAPA_1c40930 8a5c345408b89e253c45f4aab80cb71b 597 SUPERFAMILY SSF52518 3 185 6.66E-49 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold VAPA_1c40930 8a5c345408b89e253c45f4aab80cb71b 597 SUPERFAMILY SSF52518 369 568 1.71E-49 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold VAPA_1c40930 8a5c345408b89e253c45f4aab80cb71b 597 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 393 557 5.8E-33 T 12-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 VAPA_1c40930 8a5c345408b89e253c45f4aab80cb71b 597 Gene3D G3DSA:3.40.50.970 2 171 6.4E-67 T 12-10-2018 VAPA_1c40930 8a5c345408b89e253c45f4aab80cb71b 597 TIGRFAM TIGR01504 glyox_carbo_lig: glyoxylate carboligase 2 592 0.0 T 12-10-2018 IPR006397 Glyoxylate carboligase GO:0009028|GO:0009436 KEGG: 00630+4.1.1.47 VAPA_1c40930 8a5c345408b89e253c45f4aab80cb71b 597 SUPERFAMILY SSF52467 186 376 5.58E-48 T 12-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily VAPA_2c12130 aebbea4d0aabc2f46dbff12333b70763 332 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 60 328 5.7E-62 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_2c12130 aebbea4d0aabc2f46dbff12333b70763 332 Gene3D G3DSA:3.40.190.150 40 322 3.1E-88 T 12-10-2018 VAPA_2c12130 aebbea4d0aabc2f46dbff12333b70763 332 PIRSF PIRSF017082 7 332 7.5E-61 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_2c12130 aebbea4d0aabc2f46dbff12333b70763 332 Gene3D G3DSA:3.40.190.10 137 257 3.1E-88 T 12-10-2018 VAPA_1c04050 a1eae7f49e3db36773180e6f8ae6e76c 245 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 243 2.9E-54 T 12-10-2018 VAPA_1c04050 a1eae7f49e3db36773180e6f8ae6e76c 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 171 188 1.3E-35 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c04050 a1eae7f49e3db36773180e6f8ae6e76c 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 124 140 1.3E-35 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c04050 a1eae7f49e3db36773180e6f8ae6e76c 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 76 87 1.3E-35 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c04050 a1eae7f49e3db36773180e6f8ae6e76c 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 206 226 1.3E-35 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c04050 a1eae7f49e3db36773180e6f8ae6e76c 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 150 169 1.3E-35 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c04050 a1eae7f49e3db36773180e6f8ae6e76c 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 11 28 1.3E-35 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c04050 a1eae7f49e3db36773180e6f8ae6e76c 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 76 87 1.3E-8 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c04050 a1eae7f49e3db36773180e6f8ae6e76c 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 150 169 1.3E-8 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c04050 a1eae7f49e3db36773180e6f8ae6e76c 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 130 138 1.3E-8 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c04050 a1eae7f49e3db36773180e6f8ae6e76c 245 Gene3D G3DSA:3.40.50.720 1 245 6.2E-70 T 12-10-2018 VAPA_1c04050 a1eae7f49e3db36773180e6f8ae6e76c 245 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 137 165 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 VAPA_1c04050 a1eae7f49e3db36773180e6f8ae6e76c 245 SUPERFAMILY SSF51735 9 244 2.08E-69 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c35940 ab9ec446d528eb65ea5bc77a9caa08bd 238 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_1c35940 ab9ec446d528eb65ea5bc77a9caa08bd 238 SUPERFAMILY SSF52540 4 229 1.04E-53 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c35940 ab9ec446d528eb65ea5bc77a9caa08bd 238 Gene3D G3DSA:3.40.50.300 2 236 5.9E-52 T 12-10-2018 VAPA_1c35940 ab9ec446d528eb65ea5bc77a9caa08bd 238 SMART SM00382 29 217 3.1E-8 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c35940 ab9ec446d528eb65ea5bc77a9caa08bd 238 Pfam PF00005 ABC transporter 20 165 2.6E-22 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_2c02260 36cdb4a0c363a0535397d0cd8b3a6b1a 390 PIRSF PIRSF000429 1 387 2.0E-58 T 12-10-2018 IPR002155 Thiolase GO:0016747 VAPA_2c02260 36cdb4a0c363a0535397d0cd8b3a6b1a 390 Pfam PF02803 Thiolase, C-terminal domain 262 357 1.6E-8 T 12-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 VAPA_2c02260 36cdb4a0c363a0535397d0cd8b3a6b1a 390 SUPERFAMILY SSF53901 9 360 8.03E-37 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 VAPA_2c02260 36cdb4a0c363a0535397d0cd8b3a6b1a 390 Gene3D G3DSA:3.40.47.10 4 388 1.4E-90 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 VAPA_2c02260 36cdb4a0c363a0535397d0cd8b3a6b1a 390 Pfam PF00108 Thiolase, N-terminal domain 7 184 9.5E-16 T 12-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 VAPA_2c05930 2086ef094efd4040c3c1ff50092b4c38 381 SUPERFAMILY SSF47384 142 224 7.85E-19 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 VAPA_2c05930 2086ef094efd4040c3c1ff50092b4c38 381 SMART SM00388 155 223 2.2E-17 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 VAPA_2c05930 2086ef094efd4040c3c1ff50092b4c38 381 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 270 378 2.2E-25 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase VAPA_2c05930 2086ef094efd4040c3c1ff50092b4c38 381 Gene3D G3DSA:3.30.565.10 228 380 1.8E-40 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_2c05930 2086ef094efd4040c3c1ff50092b4c38 381 SUPERFAMILY SSF55874 212 377 1.44E-43 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_2c05930 2086ef094efd4040c3c1ff50092b4c38 381 PRINTS PR00344 Bacterial sensor protein C-terminal signature 339 357 3.4E-16 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_2c05930 2086ef094efd4040c3c1ff50092b4c38 381 PRINTS PR00344 Bacterial sensor protein C-terminal signature 324 334 3.4E-16 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_2c05930 2086ef094efd4040c3c1ff50092b4c38 381 PRINTS PR00344 Bacterial sensor protein C-terminal signature 363 376 3.4E-16 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_2c05930 2086ef094efd4040c3c1ff50092b4c38 381 PRINTS PR00344 Bacterial sensor protein C-terminal signature 306 320 3.4E-16 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_2c05930 2086ef094efd4040c3c1ff50092b4c38 381 Pfam PF00512 His Kinase A (phospho-acceptor) domain 156 223 8.1E-15 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 VAPA_2c05930 2086ef094efd4040c3c1ff50092b4c38 381 SMART SM00387 269 379 6.7E-38 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase VAPA_2c05930 2086ef094efd4040c3c1ff50092b4c38 381 Gene3D G3DSA:1.10.287.130 118 221 6.8E-21 T 12-10-2018 VAPA_1c52850 e98d0b4455ac3627e6eaf0c2f6f0eeca 306 Pfam PF14561 Tetratricopeptide repeat 208 303 1.4E-16 T 12-10-2018 VAPA_1c52850 e98d0b4455ac3627e6eaf0c2f6f0eeca 306 Gene3D G3DSA:1.25.40.10 120 203 8.8E-10 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 VAPA_1c52850 e98d0b4455ac3627e6eaf0c2f6f0eeca 306 Pfam PF00085 Thioredoxin 4 109 3.2E-23 T 12-10-2018 IPR013766 Thioredoxin domain GO:0045454 VAPA_1c52850 e98d0b4455ac3627e6eaf0c2f6f0eeca 306 Gene3D G3DSA:3.40.30.10 1 115 1.3E-27 T 12-10-2018 VAPA_1c52850 e98d0b4455ac3627e6eaf0c2f6f0eeca 306 PRINTS PR00421 Thioredoxin family signature 74 85 6.5E-5 T 12-10-2018 VAPA_1c52850 e98d0b4455ac3627e6eaf0c2f6f0eeca 306 PRINTS PR00421 Thioredoxin family signature 22 30 6.5E-5 T 12-10-2018 VAPA_1c52850 e98d0b4455ac3627e6eaf0c2f6f0eeca 306 PRINTS PR00421 Thioredoxin family signature 30 39 6.5E-5 T 12-10-2018 VAPA_1c52850 e98d0b4455ac3627e6eaf0c2f6f0eeca 306 SUPERFAMILY SSF48452 128 254 5.31E-8 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 VAPA_1c52850 e98d0b4455ac3627e6eaf0c2f6f0eeca 306 Gene3D G3DSA:1.25.40.10 207 304 2.3E-23 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 VAPA_1c52850 e98d0b4455ac3627e6eaf0c2f6f0eeca 306 Pfam PF14559 Tetratricopeptide repeat 128 182 2.9E-10 T 12-10-2018 VAPA_1c52850 e98d0b4455ac3627e6eaf0c2f6f0eeca 306 SUPERFAMILY SSF52833 2 112 8.85E-31 T 12-10-2018 IPR036249 Thioredoxin-like superfamily VAPA_1c52850 e98d0b4455ac3627e6eaf0c2f6f0eeca 306 ProSitePatterns PS00194 Thioredoxin family active site. 23 41 - T 12-10-2018 IPR017937 Thioredoxin, conserved site GO:0045454 VAPA_1c45120 73b7f526b55e2f874e59d7ce19390249 172 SUPERFAMILY SSF89392 39 137 5.49E-15 T 12-10-2018 IPR029046 Lipoprotein localisation LolA/LolB/LppX VAPA_1c45120 73b7f526b55e2f874e59d7ce19390249 172 Gene3D G3DSA:2.50.20.10 36 160 4.1E-11 T 12-10-2018 VAPA_1c45120 73b7f526b55e2f874e59d7ce19390249 172 Pfam PF03550 Outer membrane lipoprotein LolB 44 155 1.8E-14 T 12-10-2018 IPR004565 Outer membrane lipoprotein LolB GO:0009279|GO:0015031 VAPA_1c09980 6819cf7353a76e77c9889895ea19638d 470 SUPERFAMILY SSF53623 103 316 3.01E-53 T 12-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 VAPA_1c09980 6819cf7353a76e77c9889895ea19638d 470 SUPERFAMILY SSF53244 319 464 2.29E-31 T 12-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 VAPA_1c09980 6819cf7353a76e77c9889895ea19638d 470 TIGRFAM TIGR01081 mpl: UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-meso-diaminopimelate ligase 2 465 3.3E-199 T 12-10-2018 IPR005757 Murein peptide ligase GO:0009252|GO:0016881|GO:0071555 MetaCyc: PWY-7883 VAPA_1c09980 6819cf7353a76e77c9889895ea19638d 470 Pfam PF02875 Mur ligase family, glutamate ligase domain 319 367 4.2E-6 T 12-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 VAPA_1c09980 6819cf7353a76e77c9889895ea19638d 470 SUPERFAMILY SSF51984 1 74 4.58E-16 T 12-10-2018 VAPA_1c09980 6819cf7353a76e77c9889895ea19638d 470 Pfam PF01225 Mur ligase family, catalytic domain 2 106 3.7E-11 T 12-10-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 VAPA_1c09980 6819cf7353a76e77c9889895ea19638d 470 Hamap MF_02020 UDP-N-acetylmuramate--L-alanyl-gamma-D-glutamyl-meso-2,6-diaminoheptandioate ligase [mpl]. 1 465 57.77 T 12-10-2018 IPR005757 Murein peptide ligase GO:0009252|GO:0016881|GO:0071555 MetaCyc: PWY-7883 VAPA_1c09980 6819cf7353a76e77c9889895ea19638d 470 Pfam PF08245 Mur ligase middle domain 116 299 2.5E-25 T 12-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 VAPA_1c09980 6819cf7353a76e77c9889895ea19638d 470 Gene3D G3DSA:3.90.190.20 322 466 6.6E-21 T 12-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 VAPA_1c09980 6819cf7353a76e77c9889895ea19638d 470 Gene3D G3DSA:3.40.50.720 1 98 1.3E-31 T 12-10-2018 VAPA_1c09980 6819cf7353a76e77c9889895ea19638d 470 Gene3D G3DSA:3.40.1190.10 101 318 7.6E-60 T 12-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 VAPA_1c26520 0cd5a53c520d2a8314be8a390932f492 406 Pfam PF05977 Transmembrane secretion effector 40 396 7.4E-27 T 12-10-2018 IPR010290 Transmembrane secretion effector VAPA_1c26520 0cd5a53c520d2a8314be8a390932f492 406 Gene3D G3DSA:1.20.1250.20 5 395 3.0E-34 T 12-10-2018 VAPA_1c26520 0cd5a53c520d2a8314be8a390932f492 406 SUPERFAMILY SSF103473 7 392 1.07E-37 T 12-10-2018 IPR036259 MFS transporter superfamily VAPA_1c32990 7ce9bfd2b3f0fb480861e09b11b5979e 501 Gene3D G3DSA:2.60.120.10 348 454 7.7E-18 T 12-10-2018 IPR014710 RmlC-like jelly roll fold VAPA_1c32990 7ce9bfd2b3f0fb480861e09b11b5979e 501 SUPERFAMILY SSF53448 6 279 4.55E-62 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases VAPA_1c32990 7ce9bfd2b3f0fb480861e09b11b5979e 501 Gene3D G3DSA:3.90.550.10 5 347 7.9E-99 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases VAPA_1c32990 7ce9bfd2b3f0fb480861e09b11b5979e 501 TIGRFAM TIGR01479 GMP_PMI: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase 6 467 3.7E-171 T 12-10-2018 IPR006375 Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase GO:0000271|GO:0016779 KEGG: 00051+2.7.7.13|KEGG: 00520+2.7.7.13|MetaCyc: PWY-5659|MetaCyc: PWY-882 VAPA_1c32990 7ce9bfd2b3f0fb480861e09b11b5979e 501 SUPERFAMILY SSF51182 185 467 4.99E-69 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily VAPA_1c32990 7ce9bfd2b3f0fb480861e09b11b5979e 501 Pfam PF01050 Mannose-6-phosphate isomerase 314 463 3.1E-65 T 12-10-2018 IPR001538 Mannose-6-phosphate isomerase, type II, C-terminal GO:0005976|GO:0016779 KEGG: 00051+2.7.7.13|KEGG: 00520+2.7.7.13|MetaCyc: PWY-5659|MetaCyc: PWY-882 VAPA_1c32990 7ce9bfd2b3f0fb480861e09b11b5979e 501 Pfam PF00483 Nucleotidyl transferase 8 282 7.0E-52 T 12-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 VAPA_1c31290 4a11eec61b19abdc6de99a3542c9dffa 276 TIGRFAM TIGR03122 one_C_dehyd_C: formylmethanofuran dehydrogenase subunit C 6 273 1.0E-65 T 12-10-2018 IPR017550 Formylmethanofuran dehydrogenase subunit C GO:0015948|GO:0018493|GO:0046914|GO:0055114 KEGG: 00680+1.2.7.12|MetaCyc: PWY-5209|MetaCyc: PWY-7784 VAPA_1c31290 4a11eec61b19abdc6de99a3542c9dffa 276 Gene3D G3DSA:2.160.20.60 44 232 4.2E-23 T 12-10-2018 IPR036485 Glutamate synthase, alpha subunit, C-terminal domain superfamily GO:0016491|GO:0055114 VAPA_1c31290 4a11eec61b19abdc6de99a3542c9dffa 276 Pfam PF01493 GXGXG motif 64 211 3.7E-10 T 12-10-2018 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0016491|GO:0055114 VAPA_1c31290 4a11eec61b19abdc6de99a3542c9dffa 276 SUPERFAMILY SSF69336 15 224 2.88E-39 T 12-10-2018 IPR036485 Glutamate synthase, alpha subunit, C-terminal domain superfamily GO:0016491|GO:0055114 VAPA_1c46200 845de978e1cef4006539ec8b77e1c150 455 PRINTS PR00811 Bacterial general secretion pathway protein D signature 377 395 4.7E-15 T 12-10-2018 IPR001775 GspD/PilQ family VAPA_1c46200 845de978e1cef4006539ec8b77e1c150 455 PRINTS PR00811 Bacterial general secretion pathway protein D signature 248 272 4.7E-15 T 12-10-2018 IPR001775 GspD/PilQ family VAPA_1c46200 845de978e1cef4006539ec8b77e1c150 455 PRINTS PR00811 Bacterial general secretion pathway protein D signature 400 414 4.7E-15 T 12-10-2018 IPR001775 GspD/PilQ family VAPA_1c46200 845de978e1cef4006539ec8b77e1c150 455 PRINTS PR00811 Bacterial general secretion pathway protein D signature 170 180 4.7E-15 T 12-10-2018 IPR001775 GspD/PilQ family VAPA_1c46200 845de978e1cef4006539ec8b77e1c150 455 PRINTS PR00811 Bacterial general secretion pathway protein D signature 285 295 4.7E-15 T 12-10-2018 IPR001775 GspD/PilQ family VAPA_1c46200 845de978e1cef4006539ec8b77e1c150 455 Pfam PF13629 Pilus formation protein N terminal region 49 124 4.6E-12 T 12-10-2018 IPR032789 Pilus formation protein, N-terminal VAPA_1c46200 845de978e1cef4006539ec8b77e1c150 455 Pfam PF00263 Bacterial type II and III secretion system protein 253 413 1.3E-46 T 12-10-2018 IPR004846 Type II/III secretion system GO:0009306 VAPA_1c47610 fe94b3b76eb3e44b3ade1da8bd4887d4 271 SMART SM00421 210 267 8.4E-7 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_1c47610 fe94b3b76eb3e44b3ade1da8bd4887d4 271 SUPERFAMILY SSF46894 206 268 1.53E-11 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 VAPA_1c47610 fe94b3b76eb3e44b3ade1da8bd4887d4 271 Pfam PF00196 Bacterial regulatory proteins, luxR family 214 267 2.8E-8 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_1c47610 fe94b3b76eb3e44b3ade1da8bd4887d4 271 Gene3D G3DSA:1.10.10.10 210 270 8.9E-11 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c46740 1c822580defca6805ad1f3e8ec8841cc 409 Gene3D G3DSA:3.30.160.390 1 90 2.2E-29 T 12-10-2018 IPR038488 Integrase, DNA-binding domain superfamily VAPA_1c46740 1c822580defca6805ad1f3e8ec8841cc 409 Gene3D G3DSA:1.10.443.10 225 398 4.2E-10 T 12-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 VAPA_1c46740 1c822580defca6805ad1f3e8ec8841cc 409 Pfam PF13356 Arm DNA-binding domain 3 88 5.1E-17 T 12-10-2018 IPR025166 Integrase, DNA-binding domain VAPA_1c46740 1c822580defca6805ad1f3e8ec8841cc 409 SUPERFAMILY SSF56349 99 385 2.59E-53 T 12-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 VAPA_1c46740 1c822580defca6805ad1f3e8ec8841cc 409 Pfam PF00589 Phage integrase family 242 361 2.4E-11 T 12-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 VAPA_1c46740 1c822580defca6805ad1f3e8ec8841cc 409 Gene3D G3DSA:1.10.150.130 96 211 2.0E-29 T 12-10-2018 IPR010998 Integrase/recombinase, N-terminal VAPA_1c46740 1c822580defca6805ad1f3e8ec8841cc 409 Pfam PF14659 Phage integrase, N-terminal SAM-like domain 100 149 4.8E-5 T 12-10-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 VAPA_1c29030 57d6b246f930f39aca83cdc76af02a54 419 TIGRFAM TIGR00183 prok_nadp_idh: isocitrate dehydrogenase, NADP-dependent 4 419 1.5E-220 T 12-10-2018 IPR004439 Isocitrate dehydrogenase NADP-dependent, dimeric, prokaryotic GO:0004450|GO:0006099|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 VAPA_1c29030 57d6b246f930f39aca83cdc76af02a54 419 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 32 413 1.7E-112 T 12-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 VAPA_1c29030 57d6b246f930f39aca83cdc76af02a54 419 SUPERFAMILY SSF53659 4 419 3.26E-142 T 12-10-2018 VAPA_1c29030 57d6b246f930f39aca83cdc76af02a54 419 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 306 325 - T 12-10-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 VAPA_1c29030 57d6b246f930f39aca83cdc76af02a54 419 SMART SM01329 31 415 3.9E-168 T 12-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 VAPA_1c29030 57d6b246f930f39aca83cdc76af02a54 419 Gene3D G3DSA:3.40.718.10 1 419 1.6E-185 T 12-10-2018 VAPA_1c19710 402330da83375c019c90d68ea04a31ca 123 Gene3D G3DSA:4.10.520.10 15 111 3.4E-30 T 12-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 VAPA_1c19710 402330da83375c019c90d68ea04a31ca 123 SUPERFAMILY SSF47729 16 105 2.36E-28 T 12-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 VAPA_1c19710 402330da83375c019c90d68ea04a31ca 123 Pfam PF00216 Bacterial DNA-binding protein 16 104 1.1E-26 T 12-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 VAPA_1c19710 402330da83375c019c90d68ea04a31ca 123 Hamap MF_00380 Integration host factor subunit alpha [ihfA]. 14 110 26.948 T 12-10-2018 IPR005684 Integration host factor, alpha subunit GO:0003677|GO:0006310|GO:0006355 VAPA_1c19710 402330da83375c019c90d68ea04a31ca 123 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 61 80 - T 12-10-2018 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 VAPA_1c19710 402330da83375c019c90d68ea04a31ca 123 SMART SM00411 16 105 2.4E-30 T 12-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 VAPA_1c19710 402330da83375c019c90d68ea04a31ca 123 PRINTS PR01727 Prokaryotic integration host factor signature 89 103 2.5E-12 T 12-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 VAPA_1c19710 402330da83375c019c90d68ea04a31ca 123 PRINTS PR01727 Prokaryotic integration host factor signature 55 70 2.5E-12 T 12-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 VAPA_1c19710 402330da83375c019c90d68ea04a31ca 123 PRINTS PR01727 Prokaryotic integration host factor signature 73 86 2.5E-12 T 12-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 VAPA_1c11520 26491a253db69c3692994db75d070c48 489 Pfam PF00479 Glucose-6-phosphate dehydrogenase, NAD binding domain 6 181 4.0E-56 T 12-10-2018 IPR022674 Glucose-6-phosphate dehydrogenase, NAD-binding GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 VAPA_1c11520 26491a253db69c3692994db75d070c48 489 SUPERFAMILY SSF55347 171 486 7.19E-102 T 12-10-2018 VAPA_1c11520 26491a253db69c3692994db75d070c48 489 SUPERFAMILY SSF51735 3 184 5.91E-54 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c11520 26491a253db69c3692994db75d070c48 489 Hamap MF_00966 Glucose-6-phosphate 1-dehydrogenase [zwf]. 2 487 75.482 T 12-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 VAPA_1c11520 26491a253db69c3692994db75d070c48 489 PIRSF PIRSF000110 1 489 8.7E-162 T 12-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 VAPA_1c11520 26491a253db69c3692994db75d070c48 489 Pfam PF02781 Glucose-6-phosphate dehydrogenase, C-terminal domain 184 485 3.8E-106 T 12-10-2018 IPR022675 Glucose-6-phosphate dehydrogenase, C-terminal GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 VAPA_1c11520 26491a253db69c3692994db75d070c48 489 TIGRFAM TIGR00871 zwf: glucose-6-phosphate dehydrogenase 3 487 1.4E-162 T 12-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 VAPA_1c11520 26491a253db69c3692994db75d070c48 489 Gene3D G3DSA:3.30.360.10 171 474 9.5E-162 T 12-10-2018 VAPA_1c11520 26491a253db69c3692994db75d070c48 489 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 213 230 1.4E-42 T 12-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 VAPA_1c11520 26491a253db69c3692994db75d070c48 489 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 137 150 1.4E-42 T 12-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 VAPA_1c11520 26491a253db69c3692994db75d070c48 489 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 322 348 1.4E-42 T 12-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 VAPA_1c11520 26491a253db69c3692994db75d070c48 489 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 161 189 1.4E-42 T 12-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 VAPA_1c11520 26491a253db69c3692994db75d070c48 489 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 231 247 1.4E-42 T 12-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 VAPA_1c11520 26491a253db69c3692994db75d070c48 489 Gene3D G3DSA:3.40.50.720 5 436 9.5E-162 T 12-10-2018 VAPA_1c54800 15cd6874778634a148bebb23d6bf4926 780 Gene3D G3DSA:3.40.50.10380 11 174 2.9E-69 T 12-10-2018 IPR037062 Malic enzyme, N-terminal domain superfamily GO:0004471|GO:0055114 VAPA_1c54800 15cd6874778634a148bebb23d6bf4926 780 Pfam PF01515 Phosphate acetyl/butaryl transferase 444 773 6.4E-85 T 12-10-2018 IPR002505 Phosphate acetyl/butaryl transferase GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 VAPA_1c54800 15cd6874778634a148bebb23d6bf4926 780 Pfam PF00390 Malic enzyme, N-terminal domain 34 165 4.5E-26 T 12-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 VAPA_1c54800 15cd6874778634a148bebb23d6bf4926 780 Gene3D G3DSA:3.40.50.720 175 459 1.1E-81 T 12-10-2018 VAPA_1c54800 15cd6874778634a148bebb23d6bf4926 780 Pfam PF12434 Malate dehydrogenase enzyme 13 30 3.1E-7 T 12-10-2018 IPR032683 Malate dehydrogenase enzyme, N-terminal VAPA_1c54800 15cd6874778634a148bebb23d6bf4926 780 PIRSF PIRSF036684 13 780 0.0 T 12-10-2018 IPR012188 NAD(P)-dependent malic enzyme GO:0004470|GO:0006108|GO:0046872 KEGG: 00620+1.1.1.40|KEGG: 00710+1.1.1.40|MetaCyc: PWY-241|MetaCyc: PWY-7117 VAPA_1c54800 15cd6874778634a148bebb23d6bf4926 780 Gene3D G3DSA:3.40.50.10750 587 749 1.1E-83 T 12-10-2018 VAPA_1c54800 15cd6874778634a148bebb23d6bf4926 780 SMART SM01274 32 165 4.6E-77 T 12-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 VAPA_1c54800 15cd6874778634a148bebb23d6bf4926 780 Pfam PF03949 Malic enzyme, NAD binding domain 179 375 5.2E-23 T 12-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 VAPA_1c54800 15cd6874778634a148bebb23d6bf4926 780 SUPERFAMILY SSF53659 443 776 1.69E-82 T 12-10-2018 VAPA_1c54800 15cd6874778634a148bebb23d6bf4926 780 SMART SM00919 177 414 2.4E-132 T 12-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 VAPA_1c54800 15cd6874778634a148bebb23d6bf4926 780 SUPERFAMILY SSF51735 177 455 5.22E-84 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c54800 15cd6874778634a148bebb23d6bf4926 780 SUPERFAMILY SSF53223 24 175 7.19E-52 T 12-10-2018 VAPA_1c54800 15cd6874778634a148bebb23d6bf4926 780 Gene3D G3DSA:3.40.50.10950 460 773 1.1E-83 T 12-10-2018 VAPA_1c47650 c245e795ac365f5e272bd348bcbb7168 121 SMART SM00448 4 117 3.8E-38 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_1c47650 c245e795ac365f5e272bd348bcbb7168 121 SUPERFAMILY SSF52172 4 120 8.54E-38 T 12-10-2018 IPR011006 CheY-like superfamily VAPA_1c47650 c245e795ac365f5e272bd348bcbb7168 121 Gene3D G3DSA:3.40.50.12740 4 121 1.8E-42 T 12-10-2018 VAPA_1c47650 c245e795ac365f5e272bd348bcbb7168 121 Pfam PF00072 Response regulator receiver domain 6 117 6.6E-29 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_1c00440 e1d393f496b88df20f92d25959c420da 652 TIGRFAM TIGR00136 gidA: tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA 7 630 1.7E-273 T 12-10-2018 IPR004416 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG GO:0002098 Reactome: R-HSA-6787450 VAPA_1c00440 e1d393f496b88df20f92d25959c420da 652 SUPERFAMILY SSF51905 6 267 5.8E-49 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c00440 e1d393f496b88df20f92d25959c420da 652 ProSitePatterns PS01280 Glucose inhibited division protein A family signature 1. 279 293 - T 12-10-2018 IPR020595 MnmG-related, conserved site Reactome: R-HSA-6787450 VAPA_1c00440 e1d393f496b88df20f92d25959c420da 652 Gene3D G3DSA:1.10.10.1800 465 559 4.0E-28 T 12-10-2018 VAPA_1c00440 e1d393f496b88df20f92d25959c420da 652 Gene3D G3DSA:1.10.150.570 578 631 1.1E-24 T 12-10-2018 VAPA_1c00440 e1d393f496b88df20f92d25959c420da 652 Pfam PF01134 Glucose inhibited division protein A 8 405 7.4E-165 T 12-10-2018 IPR002218 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG-related GO:0008033|GO:0050660 Reactome: R-HSA-6787450 VAPA_1c00440 e1d393f496b88df20f92d25959c420da 652 SMART SM01228 555 626 7.3E-44 T 12-10-2018 VAPA_1c00440 e1d393f496b88df20f92d25959c420da 652 Pfam PF13932 GidA associated domain 408 625 3.5E-77 T 12-10-2018 IPR026904 GidA associated domain 3 Reactome: R-HSA-6787450 VAPA_1c00440 e1d393f496b88df20f92d25959c420da 652 ProSitePatterns PS01281 Glucose inhibited division protein A family signature 2. 374 397 - T 12-10-2018 IPR020595 MnmG-related, conserved site Reactome: R-HSA-6787450 VAPA_1c00440 e1d393f496b88df20f92d25959c420da 652 Gene3D G3DSA:3.50.50.60 2 218 4.9E-87 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c00440 e1d393f496b88df20f92d25959c420da 652 Gene3D G3DSA:3.50.50.60 301 464 2.3E-57 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c00440 e1d393f496b88df20f92d25959c420da 652 Hamap MF_00129 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG [mnmG]. 5 633 42.834 T 12-10-2018 IPR004416 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG GO:0002098 Reactome: R-HSA-6787450 VAPA_1c36430 fe0528a10dfe2080afca5178d81ef07b 698 Pfam PF00263 Bacterial type II and III secretion system protein 537 691 9.3E-45 T 12-10-2018 IPR004846 Type II/III secretion system GO:0009306 VAPA_1c36430 fe0528a10dfe2080afca5178d81ef07b 698 Pfam PF03958 Bacterial type II/III secretion system short domain 373 448 1.3E-15 T 12-10-2018 IPR005644 NolW-like VAPA_1c36430 fe0528a10dfe2080afca5178d81ef07b 698 Gene3D G3DSA:3.55.50.30 274 345 7.5E-9 T 12-10-2018 VAPA_1c36430 fe0528a10dfe2080afca5178d81ef07b 698 Gene3D G3DSA:2.60.40.3470 133 262 7.0E-39 T 12-10-2018 VAPA_1c36430 fe0528a10dfe2080afca5178d81ef07b 698 Gene3D G3DSA:2.60.40.3500 24 132 1.2E-7 T 12-10-2018 VAPA_1c36430 fe0528a10dfe2080afca5178d81ef07b 698 Gene3D G3DSA:3.30.1370.120 346 449 9.0E-24 T 12-10-2018 IPR038591 NolW-like superfamily VAPA_1c36430 fe0528a10dfe2080afca5178d81ef07b 698 PRINTS PR00811 Bacterial general secretion pathway protein D signature 679 693 4.9E-18 T 12-10-2018 IPR001775 GspD/PilQ family VAPA_1c36430 fe0528a10dfe2080afca5178d81ef07b 698 PRINTS PR00811 Bacterial general secretion pathway protein D signature 656 674 4.9E-18 T 12-10-2018 IPR001775 GspD/PilQ family VAPA_1c36430 fe0528a10dfe2080afca5178d81ef07b 698 PRINTS PR00811 Bacterial general secretion pathway protein D signature 448 458 4.9E-18 T 12-10-2018 IPR001775 GspD/PilQ family VAPA_1c36430 fe0528a10dfe2080afca5178d81ef07b 698 PRINTS PR00811 Bacterial general secretion pathway protein D signature 533 557 4.9E-18 T 12-10-2018 IPR001775 GspD/PilQ family VAPA_1c36430 fe0528a10dfe2080afca5178d81ef07b 698 SMART SM00965 300 348 1.1E-6 T 12-10-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 VAPA_1c36430 fe0528a10dfe2080afca5178d81ef07b 698 ProSitePatterns PS00875 Bacterial type II secretion system protein D signature. 637 670 - T 12-10-2018 IPR004845 Type II secretion system GspD, conserved site GO:0008565 VAPA_1c36430 fe0528a10dfe2080afca5178d81ef07b 698 TIGRFAM TIGR02515 IV_pilus_PilQ: type IV pilus secretin PilQ 275 691 8.4E-145 T 12-10-2018 IPR013355 Type IV pilus secretin PilQ VAPA_1c36430 fe0528a10dfe2080afca5178d81ef07b 698 Pfam PF11741 AMIN domain 48 131 2.2E-8 T 12-10-2018 IPR021731 AMIN domain VAPA_1c00390 687d52073041d246edac2061a3570ed1 620 Pfam PF07287 Acyclic terpene utilisation family protein AtuA 17 361 5.9E-121 T 12-10-2018 IPR010839 Acyclic terpene utilisation VAPA_1c02610 a620d3512d747132627e1e43bb4360b8 523 Pfam PF13665 Domain of unknown function (DUF4150) 26 134 6.5E-28 T 12-10-2018 IPR025425 Domain of unknown function DUF4150 VAPA_1c02610 a620d3512d747132627e1e43bb4360b8 523 Pfam PF15635 GHH signature containing HNH/Endo VII superfamily nuclease toxin 2 397 496 2.1E-23 T 12-10-2018 IPR028917 Tox-GHH2 domain VAPA_1c03440 305f3efc03d5f6ee567882a69e275348 496 TIGRFAM TIGR00132 gatA: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, A subunit 15 487 1.4E-165 T 12-10-2018 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412|GO:0030956|GO:0050567 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 VAPA_1c03440 305f3efc03d5f6ee567882a69e275348 496 SUPERFAMILY SSF75304 4 493 2.35E-153 T 12-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 VAPA_1c03440 305f3efc03d5f6ee567882a69e275348 496 Hamap MF_00120 Glutamyl-tRNA(Gln) amidotransferase subunit A [gatA]. 13 487 87.611 T 12-10-2018 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412|GO:0030956|GO:0050567 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 VAPA_1c03440 305f3efc03d5f6ee567882a69e275348 496 Gene3D G3DSA:3.90.1300.10 4 496 1.0E-185 T 12-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 VAPA_1c03440 305f3efc03d5f6ee567882a69e275348 496 Pfam PF01425 Amidase 31 476 3.1E-144 T 12-10-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 VAPA_1c00940 dcb8734506d4f22556bc0c3748153372 316 Gene3D G3DSA:3.40.50.300 134 316 1.8E-41 T 12-10-2018 VAPA_1c00940 dcb8734506d4f22556bc0c3748153372 316 SUPERFAMILY SSF47413 32 100 6.19E-13 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 VAPA_1c00940 dcb8734506d4f22556bc0c3748153372 316 Hamap MF_00109 Shikimate kinase [aroK]. 142 309 20.753 T 12-10-2018 IPR000623 Shikimate kinase/Threonine synthase-like 1 KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 VAPA_1c00940 dcb8734506d4f22556bc0c3748153372 316 Pfam PF01202 Shikimate kinase 151 302 3.4E-33 T 12-10-2018 IPR031322 Shikimate kinase/gluconokinase KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 VAPA_1c00940 dcb8734506d4f22556bc0c3748153372 316 SUPERFAMILY SSF52540 143 305 1.38E-23 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c00940 dcb8734506d4f22556bc0c3748153372 316 Pfam PF13560 Helix-turn-helix domain 36 95 3.2E-8 T 12-10-2018 VAPA_1c00940 dcb8734506d4f22556bc0c3748153372 316 Gene3D G3DSA:1.10.260.40 35 112 6.5E-13 T 12-10-2018 VAPA_1c00940 dcb8734506d4f22556bc0c3748153372 316 PRINTS PR01100 Shikimate kinase family signature 216 225 8.5E-13 T 12-10-2018 VAPA_1c00940 dcb8734506d4f22556bc0c3748153372 316 PRINTS PR01100 Shikimate kinase family signature 145 160 8.5E-13 T 12-10-2018 VAPA_1c00940 dcb8734506d4f22556bc0c3748153372 316 PRINTS PR01100 Shikimate kinase family signature 237 254 8.5E-13 T 12-10-2018 VAPA_1c00940 dcb8734506d4f22556bc0c3748153372 316 PRINTS PR01100 Shikimate kinase family signature 197 205 8.5E-13 T 12-10-2018 VAPA_1c00940 dcb8734506d4f22556bc0c3748153372 316 PRINTS PR01100 Shikimate kinase family signature 169 182 8.5E-13 T 12-10-2018 VAPA_1c00940 dcb8734506d4f22556bc0c3748153372 316 SMART SM00530 40 95 8.4E-10 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 VAPA_2c02160 acb5f1edc55c8e9da55cd83bb274981f 987 SUPERFAMILY SSF69349 443 496 1.65E-8 T 12-10-2018 VAPA_2c02160 acb5f1edc55c8e9da55cd83bb274981f 987 Gene3D G3DSA:2.40.50.230 356 458 2.0E-44 T 12-10-2018 IPR037026 Vgr protein, OB-fold domain superfamily VAPA_2c02160 acb5f1edc55c8e9da55cd83bb274981f 987 Pfam PF05954 Phage late control gene D protein (GPD) 23 329 2.5E-98 T 12-10-2018 VAPA_2c02160 acb5f1edc55c8e9da55cd83bb274981f 987 Pfam PF13296 Putative type VI secretion system Rhs element Vgr 476 584 1.7E-34 T 12-10-2018 IPR028244 Putative type VI secretion system, Rhs element associated Vgr domain VAPA_2c02160 acb5f1edc55c8e9da55cd83bb274981f 987 Pfam PF10106 Uncharacterized protein conserved in bacteria (DUF2345) 617 764 1.6E-42 T 12-10-2018 IPR018769 Domain of unknown function DUF2345, Vgr C-terminal VAPA_2c02160 acb5f1edc55c8e9da55cd83bb274981f 987 SUPERFAMILY SSF69279 182 365 2.21E-40 T 12-10-2018 VAPA_2c02160 acb5f1edc55c8e9da55cd83bb274981f 987 Gene3D G3DSA:3.55.50.10 92 183 2.5E-112 T 12-10-2018 VAPA_2c02160 acb5f1edc55c8e9da55cd83bb274981f 987 SUPERFAMILY SSF69255 365 453 4.45E-33 T 12-10-2018 VAPA_2c02160 acb5f1edc55c8e9da55cd83bb274981f 987 Gene3D G3DSA:3.30.1920.30 223 285 2.5E-112 T 12-10-2018 VAPA_2c02160 acb5f1edc55c8e9da55cd83bb274981f 987 Gene3D G3DSA:2.30.110.50 9 330 2.5E-112 T 12-10-2018 VAPA_2c02160 acb5f1edc55c8e9da55cd83bb274981f 987 TIGRFAM TIGR01646 vgr_GE: Rhs element Vgr protein 17 503 2.9E-145 T 12-10-2018 IPR006533 Type VI secretion system, RhsGE-associated Vgr protein VAPA_2c02160 acb5f1edc55c8e9da55cd83bb274981f 987 TIGRFAM TIGR03361 VI_Rhs_Vgr: type VI secretion system Vgr family protein 6 502 2.5E-171 T 12-10-2018 IPR017847 Type VI secretion system, RhsGE-associated Vgr family subset VAPA_2c02160 acb5f1edc55c8e9da55cd83bb274981f 987 SUPERFAMILY SSF69279 11 178 3.91E-58 T 12-10-2018 VAPA_1c47710 45c3287c10c0413bb09558fa27710984 325 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 50 321 3.7E-83 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c47710 45c3287c10c0413bb09558fa27710984 325 PIRSF PIRSF017082 2 324 3.0E-64 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c47710 45c3287c10c0413bb09558fa27710984 325 Gene3D G3DSA:3.40.190.150 29 315 4.6E-101 T 12-10-2018 VAPA_1c47710 45c3287c10c0413bb09558fa27710984 325 SUPERFAMILY SSF53850 112 282 7.61E-14 T 12-10-2018 VAPA_1c47710 45c3287c10c0413bb09558fa27710984 325 Gene3D G3DSA:3.40.190.10 127 250 4.6E-101 T 12-10-2018 VAPA_1c51660 42ca91111b0c21d9d90a2a97ff5d46da 681 PIRSF PIRSF002583 2 681 1.6E-207 T 12-10-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0051082 VAPA_1c51660 42ca91111b0c21d9d90a2a97ff5d46da 681 Hamap MF_00505 Chaperone protein HtpG [htpG]. 3 681 31.875 T 12-10-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0051082 VAPA_1c51660 42ca91111b0c21d9d90a2a97ff5d46da 681 Pfam PF00183 Hsp90 protein 230 680 7.6E-124 T 12-10-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0051082 VAPA_1c51660 42ca91111b0c21d9d90a2a97ff5d46da 681 SUPERFAMILY SSF110942 571 680 1.31E-32 T 12-10-2018 IPR037196 HSP90, C-terminal domain VAPA_1c51660 42ca91111b0c21d9d90a2a97ff5d46da 681 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 29 184 7.4E-12 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase VAPA_1c51660 42ca91111b0c21d9d90a2a97ff5d46da 681 SUPERFAMILY SSF54211 240 545 1.29E-92 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold VAPA_1c51660 42ca91111b0c21d9d90a2a97ff5d46da 681 Gene3D G3DSA:3.40.50.11260 459 546 1.5E-32 T 12-10-2018 VAPA_1c51660 42ca91111b0c21d9d90a2a97ff5d46da 681 Gene3D G3DSA:1.20.120.790 551 681 1.9E-41 T 12-10-2018 IPR037196 HSP90, C-terminal domain VAPA_1c51660 42ca91111b0c21d9d90a2a97ff5d46da 681 Gene3D G3DSA:3.30.230.80 239 388 1.9E-55 T 12-10-2018 VAPA_1c51660 42ca91111b0c21d9d90a2a97ff5d46da 681 SMART SM00387 29 186 5.2E-6 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase VAPA_1c51660 42ca91111b0c21d9d90a2a97ff5d46da 681 SUPERFAMILY SSF55874 8 218 2.88E-63 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_1c51660 42ca91111b0c21d9d90a2a97ff5d46da 681 ProSitePatterns PS00298 Heat shock hsp90 proteins family signature. 27 36 - T 12-10-2018 IPR019805 Heat shock protein Hsp90, conserved site GO:0005524|GO:0006457|GO:0051082 VAPA_1c51660 42ca91111b0c21d9d90a2a97ff5d46da 681 Gene3D G3DSA:3.30.230.80 404 458 6.1E-6 T 12-10-2018 VAPA_1c51660 42ca91111b0c21d9d90a2a97ff5d46da 681 Gene3D G3DSA:3.30.565.10 1 229 9.2E-75 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_1c51660 42ca91111b0c21d9d90a2a97ff5d46da 681 PRINTS PR00775 90kDa heat shock protein signature 95 112 3.1E-60 T 12-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal VAPA_1c51660 42ca91111b0c21d9d90a2a97ff5d46da 681 PRINTS PR00775 90kDa heat shock protein signature 28 50 3.1E-60 T 12-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal VAPA_1c51660 42ca91111b0c21d9d90a2a97ff5d46da 681 PRINTS PR00775 90kDa heat shock protein signature 192 210 3.1E-60 T 12-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal VAPA_1c51660 42ca91111b0c21d9d90a2a97ff5d46da 681 PRINTS PR00775 90kDa heat shock protein signature 122 144 3.1E-60 T 12-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal VAPA_1c51660 42ca91111b0c21d9d90a2a97ff5d46da 681 PRINTS PR00775 90kDa heat shock protein signature 77 94 3.1E-60 T 12-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal VAPA_1c51660 42ca91111b0c21d9d90a2a97ff5d46da 681 PRINTS PR00775 90kDa heat shock protein signature 7 27 3.1E-60 T 12-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal VAPA_1c51660 42ca91111b0c21d9d90a2a97ff5d46da 681 PRINTS PR00775 90kDa heat shock protein signature 174 191 3.1E-60 T 12-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal VAPA_1c36050 d5a9dd332b15a3d6d4e43f556aac08ee 495 TIGRFAM TIGR01770 NDH_I_N: proton-translocating NADH-quinone oxidoreductase, chain N 7 479 7.5E-131 T 12-10-2018 IPR010096 NAD(P)H-quinone oxidoreductase, subunit N/subunit 2 GO:0008137|GO:0042773|GO:0055114 VAPA_1c36050 d5a9dd332b15a3d6d4e43f556aac08ee 495 Pfam PF00361 Proton-conducting membrane transporter 128 428 2.5E-73 T 12-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VAPA_1c36050 d5a9dd332b15a3d6d4e43f556aac08ee 495 Hamap MF_00445 NAD(P)H-quinone oxidoreductase subunit 2, chloroplastic [ndhB]. 5 482 18.052 T 12-10-2018 IPR010096 NAD(P)H-quinone oxidoreductase, subunit N/subunit 2 GO:0008137|GO:0042773|GO:0055114 VAPA_1c36050 d5a9dd332b15a3d6d4e43f556aac08ee 495 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 217 238 9.0E-7 T 12-10-2018 VAPA_1c36050 d5a9dd332b15a3d6d4e43f556aac08ee 495 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 309 321 9.0E-7 T 12-10-2018 VAPA_1c36050 d5a9dd332b15a3d6d4e43f556aac08ee 495 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 425 444 9.0E-7 T 12-10-2018 VAPA_1c36050 d5a9dd332b15a3d6d4e43f556aac08ee 495 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 73 98 9.0E-7 T 12-10-2018 VAPA_2c08950 a138b50fb48022704a91cea0739f55fd 201 PIRSF PIRSF029681 9 201 2.9E-40 T 12-10-2018 IPR018550 Lipid A 3-O-deacylase-related VAPA_2c08950 a138b50fb48022704a91cea0739f55fd 201 Gene3D G3DSA:2.40.160.20 50 200 1.7E-38 T 12-10-2018 VAPA_2c08950 a138b50fb48022704a91cea0739f55fd 201 Pfam PF09411 Lipid A 3-O-deacylase (PagL) 64 198 7.0E-35 T 12-10-2018 IPR018550 Lipid A 3-O-deacylase-related VAPA_1c52420 62437c35bee66fcb4fc8d96bea493478 437 Pfam PF00344 SecY translocase 74 413 2.3E-115 T 12-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 VAPA_1c52420 62437c35bee66fcb4fc8d96bea493478 437 SUPERFAMILY SSF103491 7 420 4.84E-129 T 12-10-2018 IPR023201 SecY domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 VAPA_1c52420 62437c35bee66fcb4fc8d96bea493478 437 Hamap MF_01465 Protein translocase subunit SecY [secY]. 8 429 29.621 T 12-10-2018 IPR026593 Protein translocase subunit SecY VAPA_1c52420 62437c35bee66fcb4fc8d96bea493478 437 PRINTS PR00303 Preprotein translocase SecY subunit signature 149 174 8.3E-93 T 12-10-2018 VAPA_1c52420 62437c35bee66fcb4fc8d96bea493478 437 PRINTS PR00303 Preprotein translocase SecY subunit signature 175 198 8.3E-93 T 12-10-2018 VAPA_1c52420 62437c35bee66fcb4fc8d96bea493478 437 PRINTS PR00303 Preprotein translocase SecY subunit signature 21 39 8.3E-93 T 12-10-2018 VAPA_1c52420 62437c35bee66fcb4fc8d96bea493478 437 PRINTS PR00303 Preprotein translocase SecY subunit signature 114 137 8.3E-93 T 12-10-2018 VAPA_1c52420 62437c35bee66fcb4fc8d96bea493478 437 PRINTS PR00303 Preprotein translocase SecY subunit signature 311 333 8.3E-93 T 12-10-2018 VAPA_1c52420 62437c35bee66fcb4fc8d96bea493478 437 PRINTS PR00303 Preprotein translocase SecY subunit signature 267 286 8.3E-93 T 12-10-2018 VAPA_1c52420 62437c35bee66fcb4fc8d96bea493478 437 PRINTS PR00303 Preprotein translocase SecY subunit signature 73 93 8.3E-93 T 12-10-2018 VAPA_1c52420 62437c35bee66fcb4fc8d96bea493478 437 PRINTS PR00303 Preprotein translocase SecY subunit signature 366 384 8.3E-93 T 12-10-2018 VAPA_1c52420 62437c35bee66fcb4fc8d96bea493478 437 PRINTS PR00303 Preprotein translocase SecY subunit signature 398 416 8.3E-93 T 12-10-2018 VAPA_1c52420 62437c35bee66fcb4fc8d96bea493478 437 ProSitePatterns PS00756 Protein secY signature 2. 168 185 - T 12-10-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 VAPA_1c52420 62437c35bee66fcb4fc8d96bea493478 437 PIRSF PIRSF004557 1 437 8.7E-122 T 12-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 VAPA_1c52420 62437c35bee66fcb4fc8d96bea493478 437 Gene3D G3DSA:1.10.3370.10 6 425 1.2E-160 T 12-10-2018 IPR023201 SecY domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 VAPA_1c52420 62437c35bee66fcb4fc8d96bea493478 437 ProSitePatterns PS00755 Protein secY signature 1. 74 93 - T 12-10-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 VAPA_1c52420 62437c35bee66fcb4fc8d96bea493478 437 TIGRFAM TIGR00967 3a0501s007: preprotein translocase, SecY subunit 18 425 5.5E-131 T 12-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 VAPA_1c35780 146ee8c1a18db6f634fd60fc23625c0f 318 PIRSF PIRSF006278 51 318 5.5E-8 T 12-10-2018 IPR027278 1-aminocyclopropane-1-carboxylate deaminase/D-cysteine desulfhydrase VAPA_1c35780 146ee8c1a18db6f634fd60fc23625c0f 318 SUPERFAMILY SSF53686 5 313 1.19E-95 T 12-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme VAPA_1c35780 146ee8c1a18db6f634fd60fc23625c0f 318 Gene3D G3DSA:3.40.50.1100 52 148 3.3E-117 T 12-10-2018 VAPA_1c35780 146ee8c1a18db6f634fd60fc23625c0f 318 Gene3D G3DSA:3.40.50.1100 15 309 3.3E-117 T 12-10-2018 VAPA_1c35780 146ee8c1a18db6f634fd60fc23625c0f 318 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 17 305 6.6E-80 T 12-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme VAPA_1c25660 f535b8f76f6410067685f01915dbec9a 233 Hamap MF_01401 Peptide methionine sulfoxide reductase MsrA [msrA]. 46 206 34.869 T 12-10-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 VAPA_1c25660 f535b8f76f6410067685f01915dbec9a 233 Pfam PF01625 Peptide methionine sulfoxide reductase 49 200 1.3E-55 T 12-10-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 VAPA_1c25660 f535b8f76f6410067685f01915dbec9a 233 SUPERFAMILY SSF55068 40 210 7.06E-65 T 12-10-2018 IPR036509 Peptide methionine sulphoxide reductase MsrA superfamily GO:0008113|GO:0055114 Reactome: R-HSA-5676934 VAPA_1c25660 f535b8f76f6410067685f01915dbec9a 233 TIGRFAM TIGR00401 msrA: peptide-methionine (S)-S-oxide reductase 48 198 6.0E-51 T 12-10-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 VAPA_1c25660 f535b8f76f6410067685f01915dbec9a 233 Gene3D G3DSA:3.30.1060.10 15 207 6.0E-61 T 12-10-2018 IPR036509 Peptide methionine sulphoxide reductase MsrA superfamily GO:0008113|GO:0055114 Reactome: R-HSA-5676934 VAPA_2c06120 48a77279933277f6e320fea546e9c315 597 SUPERFAMILY SSF51905 136 580 9.32E-20 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_2c06120 48a77279933277f6e320fea546e9c315 597 Gene3D G3DSA:3.30.9.10 283 530 4.8E-15 T 12-10-2018 VAPA_2c06120 48a77279933277f6e320fea546e9c315 597 Gene3D G3DSA:3.50.50.60 243 570 4.8E-15 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_2c06120 48a77279933277f6e320fea546e9c315 597 Gene3D G3DSA:3.50.50.60 124 236 3.1E-5 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_2c06120 48a77279933277f6e320fea546e9c315 597 Pfam PF01266 FAD dependent oxidoreductase 136 570 5.9E-18 T 12-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 VAPA_1c33200 36b3ee91de8bb5af3f2fb291b994e3f7 620 Pfam PF00005 ABC transporter 378 531 5.5E-34 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c33200 36b3ee91de8bb5af3f2fb291b994e3f7 620 Pfam PF00664 ABC transporter transmembrane region 42 306 2.6E-14 T 12-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 VAPA_1c33200 36b3ee91de8bb5af3f2fb291b994e3f7 620 SUPERFAMILY SSF52540 352 601 5.92E-88 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c33200 36b3ee91de8bb5af3f2fb291b994e3f7 620 ProSitePatterns PS00211 ABC transporters family signature. 503 517 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_1c33200 36b3ee91de8bb5af3f2fb291b994e3f7 620 SMART SM00382 386 577 4.8E-19 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c33200 36b3ee91de8bb5af3f2fb291b994e3f7 620 Gene3D G3DSA:1.20.1560.10 14 350 1.3E-25 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 VAPA_1c33200 36b3ee91de8bb5af3f2fb291b994e3f7 620 Gene3D G3DSA:3.40.50.300 351 605 1.7E-90 T 12-10-2018 VAPA_1c33200 36b3ee91de8bb5af3f2fb291b994e3f7 620 SUPERFAMILY SSF90123 28 341 1.15E-47 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 VAPA_1c03690 c169ee9ea446162d51b21fbfc448ac65 471 Gene3D G3DSA:3.50.50.60 11 322 1.5E-33 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c03690 c169ee9ea446162d51b21fbfc448ac65 471 Gene3D G3DSA:3.50.50.60 127 268 1.5E-33 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c03690 c169ee9ea446162d51b21fbfc448ac65 471 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 11 326 1.1E-21 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 VAPA_1c03690 c169ee9ea446162d51b21fbfc448ac65 471 Gene3D G3DSA:1.10.10.1100 371 444 1.8E-20 T 12-10-2018 VAPA_1c03690 c169ee9ea446162d51b21fbfc448ac65 471 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 115 133 1.0E-9 T 12-10-2018 VAPA_1c03690 c169ee9ea446162d51b21fbfc448ac65 471 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 292 314 1.0E-9 T 12-10-2018 VAPA_1c03690 c169ee9ea446162d51b21fbfc448ac65 471 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 10 29 1.0E-9 T 12-10-2018 VAPA_1c03690 c169ee9ea446162d51b21fbfc448ac65 471 SUPERFAMILY SSF51905 11 334 1.21E-30 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c03690 c169ee9ea446162d51b21fbfc448ac65 471 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 9 31 5.6E-6 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 VAPA_1c03690 c169ee9ea446162d51b21fbfc448ac65 471 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 302 320 5.6E-6 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 VAPA_1c03690 c169ee9ea446162d51b21fbfc448ac65 471 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 116 124 5.6E-6 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 VAPA_1c03690 c169ee9ea446162d51b21fbfc448ac65 471 PIRSF PIRSF037495 1 469 2.6E-134 T 12-10-2018 IPR017224 Opine oxidase, subunit A/hydrogen cyanide synthase, subunit B GO:0016491|GO:0055114 VAPA_1c03690 c169ee9ea446162d51b21fbfc448ac65 471 Pfam PF04324 BFD-like [2Fe-2S] binding domain 382 434 4.2E-11 T 12-10-2018 IPR007419 BFD-like [2Fe-2S]-binding domain VAPA_1c53310 47f6f6ee938e0632746d17139da70ee2 154 Pfam PF01042 Endoribonuclease L-PSP 53 147 7.5E-11 T 12-10-2018 IPR006175 YjgF/YER057c/UK114 family Reactome: R-HSA-8849175 VAPA_1c53310 47f6f6ee938e0632746d17139da70ee2 154 Gene3D G3DSA:3.30.1330.40 1 154 7.8E-40 T 12-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 VAPA_1c53310 47f6f6ee938e0632746d17139da70ee2 154 SUPERFAMILY SSF55298 5 150 2.83E-22 T 12-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 VAPA_1c36440 a3f44e36e1cbcddfc8cc7ed5d947cf3a 370 ProSitePatterns PS00211 ABC transporters family signature. 143 157 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_1c36440 a3f44e36e1cbcddfc8cc7ed5d947cf3a 370 SMART SM00382 37 222 2.1E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c36440 a3f44e36e1cbcddfc8cc7ed5d947cf3a 370 Pfam PF00005 ABC transporter 29 170 1.1E-32 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c36440 a3f44e36e1cbcddfc8cc7ed5d947cf3a 370 SUPERFAMILY SSF52540 11 249 1.77E-83 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c36440 a3f44e36e1cbcddfc8cc7ed5d947cf3a 370 Gene3D G3DSA:3.40.50.300 9 263 1.0E-71 T 12-10-2018 VAPA_1c36440 a3f44e36e1cbcddfc8cc7ed5d947cf3a 370 Pfam PF08402 TOBE domain 256 336 1.8E-10 T 12-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 VAPA_1c45570 3955daa56434a6518011ff1dd229bdb3 227 SUPERFAMILY SSF52833 60 202 7.21E-10 T 12-10-2018 IPR036249 Thioredoxin-like superfamily VAPA_1c45570 3955daa56434a6518011ff1dd229bdb3 227 Gene3D G3DSA:3.40.30.10 70 154 4.2E-7 T 12-10-2018 VAPA_1c21110 e4274f672d88f3cc77778d27d688e4c9 1109 Gene3D G3DSA:3.90.400.10 121 191 6.4E-213 T 12-10-2018 VAPA_1c21110 e4274f672d88f3cc77778d27d688e4c9 1109 SUPERFAMILY SSF51011 481 558 7.2E-15 T 12-10-2018 VAPA_1c21110 e4274f672d88f3cc77778d27d688e4c9 1109 TIGRFAM TIGR02457 TreS_Cterm: putative maltokinase 593 1103 4.5E-132 T 12-10-2018 IPR012811 Trehalose synthase/probable maltokinase, C-terminal domain VAPA_1c21110 e4274f672d88f3cc77778d27d688e4c9 1109 Gene3D G3DSA:2.60.40.1180 478 569 1.9E-31 T 12-10-2018 IPR013780 Glycosyl hydrolase, all-beta VAPA_1c21110 e4274f672d88f3cc77778d27d688e4c9 1109 Gene3D G3DSA:3.20.20.80 23 471 6.4E-213 T 12-10-2018 VAPA_1c21110 e4274f672d88f3cc77778d27d688e4c9 1109 SUPERFAMILY SSF51445 36 478 8.21E-129 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily VAPA_1c21110 e4274f672d88f3cc77778d27d688e4c9 1109 SUPERFAMILY SSF56112 756 1093 5.1E-15 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily VAPA_1c21110 e4274f672d88f3cc77778d27d688e4c9 1109 SMART SM00642 31 430 4.7E-101 T 12-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 VAPA_1c21110 e4274f672d88f3cc77778d27d688e4c9 1109 Pfam PF00128 Alpha amylase, catalytic domain 46 399 2.2E-73 T 12-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 VAPA_1c21110 e4274f672d88f3cc77778d27d688e4c9 1109 Pfam PF16657 Maltogenic Amylase, C-terminal domain 478 555 2.2E-27 T 12-10-2018 IPR032091 Maltogenic Amylase, C-terminal VAPA_1c21110 e4274f672d88f3cc77778d27d688e4c9 1109 Gene3D G3DSA:3.90.1200.10 828 1107 3.3E-61 T 12-10-2018 VAPA_1c21110 e4274f672d88f3cc77778d27d688e4c9 1109 TIGRFAM TIGR02456 treS_nterm: trehalose synthase 23 558 2.4E-279 T 12-10-2018 IPR012810 Trehalose synthase/alpha-amylase, N-terminal GO:0003824|GO:0005975 KEGG: 00500+5.4.99.16|MetaCyc: PWY-2622|MetaCyc: PWY-7900 VAPA_1c48330 6ca4ee7786925fe845749bd9300bb66d 274 TIGRFAM TIGR00676 fadh2: methylenetetrahydrofolate reductase [NAD(P)H] 5 273 4.9E-91 T 12-10-2018 IPR004620 5,10-methylenetetrahydrofolate reductase GO:0004489|GO:0005829|GO:0009086|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841 VAPA_1c48330 6ca4ee7786925fe845749bd9300bb66d 274 SUPERFAMILY SSF51730 4 274 6.08E-91 T 12-10-2018 IPR029041 FAD-linked oxidoreductase-like VAPA_1c48330 6ca4ee7786925fe845749bd9300bb66d 274 Pfam PF02219 Methylenetetrahydrofolate reductase 5 274 9.9E-82 T 12-10-2018 IPR003171 Methylenetetrahydrofolate reductase GO:0004489|GO:0006555|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 VAPA_1c48330 6ca4ee7786925fe845749bd9300bb66d 274 Gene3D G3DSA:3.20.20.220 2 274 1.5E-91 T 12-10-2018 VAPA_1c15230 d84278364b23eaa2189cb8fd4b9f7dca 148 PIRSF PIRSF000178 12 145 3.3E-27 T 12-10-2018 IPR014314 Succinate dehydrogenase, cytochrome b556 subunit GO:0000104|GO:0006099|GO:0045281 Reactome: R-HSA-611105|Reactome: R-HSA-71403 VAPA_1c15230 d84278364b23eaa2189cb8fd4b9f7dca 148 TIGRFAM TIGR02970 succ_dehyd_cytB: succinate dehydrogenase, cytochrome b556 subunit 21 141 4.5E-31 T 12-10-2018 IPR014314 Succinate dehydrogenase, cytochrome b556 subunit GO:0000104|GO:0006099|GO:0045281 Reactome: R-HSA-611105|Reactome: R-HSA-71403 VAPA_1c15230 d84278364b23eaa2189cb8fd4b9f7dca 148 Pfam PF01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 20 140 4.9E-28 T 12-10-2018 IPR000701 Succinate dehydrogenase/fumarate reductase type B, transmembrane subunit GO:0016627 Reactome: R-HSA-611105|Reactome: R-HSA-71403 VAPA_1c15230 d84278364b23eaa2189cb8fd4b9f7dca 148 Gene3D G3DSA:1.20.1300.10 13 145 6.7E-34 T 12-10-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 VAPA_1c15230 d84278364b23eaa2189cb8fd4b9f7dca 148 SUPERFAMILY SSF81343 23 144 1.0E-25 T 12-10-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 VAPA_1c38320 3a52ea1945203649023b3ddf2da8d9f1 211 ProSitePatterns PS00159 KDPG and KHG aldolases active site. 39 48 - T 12-10-2018 IPR031337 KDPG/KHG aldolase, active site 1 KEGG: 00030+4.1.2.14|KEGG: 00330+4.1.3.16|KEGG: 00630+4.1.3.16|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 VAPA_1c38320 3a52ea1945203649023b3ddf2da8d9f1 211 Gene3D G3DSA:3.20.20.70 2 210 6.6E-73 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 VAPA_1c38320 3a52ea1945203649023b3ddf2da8d9f1 211 ProSitePatterns PS00160 KDPG and KHG aldolases Schiff-base forming residue. 127 140 - T 12-10-2018 IPR031338 KDPG/KHG aldolase, active site 2 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 VAPA_1c38320 3a52ea1945203649023b3ddf2da8d9f1 211 Pfam PF01081 KDPG and KHG aldolase 10 202 1.4E-71 T 12-10-2018 IPR000887 KDPG/KHG aldolase GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 VAPA_1c38320 3a52ea1945203649023b3ddf2da8d9f1 211 TIGRFAM TIGR01182 eda: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase 10 208 4.1E-75 T 12-10-2018 IPR000887 KDPG/KHG aldolase GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 VAPA_1c38320 3a52ea1945203649023b3ddf2da8d9f1 211 SUPERFAMILY SSF51569 4 209 1.78E-68 T 12-10-2018 VAPA_1c41110 79f25e78baf69332e62cb2b0e18edd75 289 Gene3D G3DSA:3.40.50.720 1 161 4.0E-38 T 12-10-2018 VAPA_1c41110 79f25e78baf69332e62cb2b0e18edd75 289 SUPERFAMILY SSF51735 4 162 1.5E-28 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c41110 79f25e78baf69332e62cb2b0e18edd75 289 SUPERFAMILY SSF48179 169 288 2.15E-5 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 VAPA_1c41110 79f25e78baf69332e62cb2b0e18edd75 289 PIRSF PIRSF000103 1 289 4.0E-41 T 12-10-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 VAPA_1c41110 79f25e78baf69332e62cb2b0e18edd75 289 Gene3D G3DSA:1.10.1040.10 163 289 2.1E-30 T 12-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 VAPA_1c41110 79f25e78baf69332e62cb2b0e18edd75 289 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 6 162 4.8E-22 T 12-10-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 VAPA_1c12220 685200077881209ea5d8a791be6f8bfc 429 Gene3D G3DSA:3.65.10.10 21 233 1.6E-163 T 12-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 VAPA_1c12220 685200077881209ea5d8a791be6f8bfc 429 SUPERFAMILY SSF55205 1 425 8.83E-139 T 12-10-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 VAPA_1c12220 685200077881209ea5d8a791be6f8bfc 429 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 7 414 7.6E-109 T 12-10-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 VAPA_1c12220 685200077881209ea5d8a791be6f8bfc 429 TIGRFAM TIGR01072 murA: UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1 423 3.4E-175 T 12-10-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 VAPA_1c12220 685200077881209ea5d8a791be6f8bfc 429 Hamap MF_00111 UDP-N-acetylglucosamine 1-carboxyvinyltransferase [murA]. 1 424 44.608 T 12-10-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 VAPA_1c12220 685200077881209ea5d8a791be6f8bfc 429 Gene3D G3DSA:3.65.10.10 6 421 1.6E-163 T 12-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 VAPA_1c32770 94c706759ca82aa5802d7b2c0063b583 508 SMART SM00885 82 221 3.3E-7 T 12-10-2018 IPR014818 Bacteriophage/plasmid primase, P4, C-terminal VAPA_1c32770 94c706759ca82aa5802d7b2c0063b583 508 Pfam PF08706 D5 N terminal like 92 220 4.2E-16 T 12-10-2018 IPR014818 Bacteriophage/plasmid primase, P4, C-terminal VAPA_1c32770 94c706759ca82aa5802d7b2c0063b583 508 TIGRFAM TIGR01613 primase_Cterm: phage/plasmid primase, P4 family, C-terminal domain 172 467 1.7E-77 T 12-10-2018 IPR006500 DNA primase, phage/plasmid VAPA_1c13690 afa6303d2e21cf3622a4f6f874c21026 300 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 7 287 9.2E-65 T 12-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme VAPA_1c13690 afa6303d2e21cf3622a4f6f874c21026 300 SUPERFAMILY SSF53686 3 298 6.55E-90 T 12-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme VAPA_1c13690 afa6303d2e21cf3622a4f6f874c21026 300 Gene3D G3DSA:3.40.50.1100 41 146 2.9E-108 T 12-10-2018 VAPA_1c13690 afa6303d2e21cf3622a4f6f874c21026 300 Gene3D G3DSA:3.40.50.1100 10 294 2.9E-108 T 12-10-2018 VAPA_1c13690 afa6303d2e21cf3622a4f6f874c21026 300 TIGRFAM TIGR01138 cysM: cysteine synthase B 5 298 1.7E-136 T 12-10-2018 IPR005858 Cysteine synthase CysM GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 VAPA_1c13690 afa6303d2e21cf3622a4f6f874c21026 300 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 36 54 - T 12-10-2018 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 VAPA_1c13690 afa6303d2e21cf3622a4f6f874c21026 300 TIGRFAM TIGR01136 cysKM: cysteine synthase 6 298 1.1E-117 T 12-10-2018 IPR005856 Cysteine synthase GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 VAPA_2c03140 4b003dfdb802a3025b326f3e6acf17e5 299 Gene3D G3DSA:3.40.190.10 93 284 1.3E-41 T 12-10-2018 VAPA_2c03140 4b003dfdb802a3025b326f3e6acf17e5 299 SUPERFAMILY SSF53850 88 294 7.82E-35 T 12-10-2018 VAPA_2c03140 4b003dfdb802a3025b326f3e6acf17e5 299 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 3.0E-19 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_2c03140 4b003dfdb802a3025b326f3e6acf17e5 299 Gene3D G3DSA:1.10.10.10 1 88 2.5E-23 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_2c03140 4b003dfdb802a3025b326f3e6acf17e5 299 Pfam PF03466 LysR substrate binding domain 87 293 7.0E-34 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_2c03140 4b003dfdb802a3025b326f3e6acf17e5 299 SUPERFAMILY SSF46785 1 109 8.08E-22 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_2c03140 4b003dfdb802a3025b326f3e6acf17e5 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.5E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_2c03140 4b003dfdb802a3025b326f3e6acf17e5 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.5E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_2c03140 4b003dfdb802a3025b326f3e6acf17e5 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.5E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_2c03140 4b003dfdb802a3025b326f3e6acf17e5 299 Gene3D G3DSA:3.40.190.10 164 266 1.3E-41 T 12-10-2018 VAPA_1c43730 07c99bfe641b1ee9e1b6f153e1b60e2a 362 Gene3D G3DSA:2.70.210.12 1 158 7.3E-56 T 12-10-2018 IPR036726 GTP1/OBG domain superfamily VAPA_1c43730 07c99bfe641b1ee9e1b6f153e1b60e2a 362 PIRSF PIRSF002401 1 349 4.0E-133 T 12-10-2018 IPR035101 GTP-binding protein, Obg-type VAPA_1c43730 07c99bfe641b1ee9e1b6f153e1b60e2a 362 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 183 201 4.3E-35 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 VAPA_1c43730 07c99bfe641b1ee9e1b6f153e1b60e2a 362 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 162 182 4.3E-35 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 VAPA_1c43730 07c99bfe641b1ee9e1b6f153e1b60e2a 362 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 228 246 4.3E-35 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 VAPA_1c43730 07c99bfe641b1ee9e1b6f153e1b60e2a 362 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 211 226 4.3E-35 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 VAPA_1c43730 07c99bfe641b1ee9e1b6f153e1b60e2a 362 SUPERFAMILY SSF82051 2 158 3.66E-54 T 12-10-2018 IPR036726 GTP1/OBG domain superfamily VAPA_1c43730 07c99bfe641b1ee9e1b6f153e1b60e2a 362 SUPERFAMILY SSF52540 152 337 9.1E-52 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c43730 07c99bfe641b1ee9e1b6f153e1b60e2a 362 Gene3D G3DSA:3.40.50.300 159 340 7.7E-54 T 12-10-2018 VAPA_1c43730 07c99bfe641b1ee9e1b6f153e1b60e2a 362 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 161 329 2.8E-14 T 12-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 VAPA_1c43730 07c99bfe641b1ee9e1b6f153e1b60e2a 362 Pfam PF01926 50S ribosome-binding GTPase 161 285 1.2E-24 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 VAPA_1c43730 07c99bfe641b1ee9e1b6f153e1b60e2a 362 Pfam PF01018 GTP1/OBG 4 158 1.4E-55 T 12-10-2018 IPR006169 GTP1/OBG domain VAPA_1c43730 07c99bfe641b1ee9e1b6f153e1b60e2a 362 ProSitePatterns PS00905 GTP1/OBG family signature. 213 226 - T 12-10-2018 IPR006074 GTP1/OBG, conserved site GO:0005525 VAPA_1c43730 07c99bfe641b1ee9e1b6f153e1b60e2a 362 TIGRFAM TIGR02729 Obg_CgtA: Obg family GTPase CgtA 3 333 4.5E-140 T 12-10-2018 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 VAPA_1c43730 07c99bfe641b1ee9e1b6f153e1b60e2a 362 Hamap MF_01454 GTPase Obg [obg]. 2 334 46.887 T 12-10-2018 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 VAPA_1c34490 8475bdfb9f06e8b80d11b96cf201e2c5 370 Hamap MF_00300 Chorismate synthase [aroC]. 10 353 34.927 T 12-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 VAPA_1c34490 8475bdfb9f06e8b80d11b96cf201e2c5 370 TIGRFAM TIGR00033 aroC: chorismate synthase 10 348 2.4E-134 T 12-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 VAPA_1c34490 8475bdfb9f06e8b80d11b96cf201e2c5 370 ProSitePatterns PS00788 Chorismate synthase signature 2. 124 140 - T 12-10-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 VAPA_1c34490 8475bdfb9f06e8b80d11b96cf201e2c5 370 PIRSF PIRSF001456 3 364 6.6E-133 T 12-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 VAPA_1c34490 8475bdfb9f06e8b80d11b96cf201e2c5 370 SUPERFAMILY SSF103263 4 355 2.49E-139 T 12-10-2018 IPR035904 Chorismate synthase AroC superfamily KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 VAPA_1c34490 8475bdfb9f06e8b80d11b96cf201e2c5 370 Gene3D G3DSA:3.60.150.10 1 362 3.4E-145 T 12-10-2018 IPR035904 Chorismate synthase AroC superfamily KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 VAPA_1c34490 8475bdfb9f06e8b80d11b96cf201e2c5 370 ProSitePatterns PS00787 Chorismate synthase signature 1. 16 31 - T 12-10-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 VAPA_1c34490 8475bdfb9f06e8b80d11b96cf201e2c5 370 ProSitePatterns PS00789 Chorismate synthase signature 3. 318 334 - T 12-10-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 VAPA_1c34490 8475bdfb9f06e8b80d11b96cf201e2c5 370 Pfam PF01264 Chorismate synthase 10 344 9.0E-131 T 12-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 VAPA_2c01350 797b76f184e80aa85e6a50b7890f9f0d 276 Gene3D G3DSA:3.40.50.720 1 175 1.1E-51 T 12-10-2018 VAPA_2c01350 797b76f184e80aa85e6a50b7890f9f0d 276 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 5 90 1.6E-5 T 12-10-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal VAPA_2c01350 797b76f184e80aa85e6a50b7890f9f0d 276 Gene3D G3DSA:1.10.3640.10 176 276 2.0E-37 T 12-10-2018 IPR037161 Semialdehyde dehydrogenase-like, C-terminal VAPA_2c01350 797b76f184e80aa85e6a50b7890f9f0d 276 SUPERFAMILY SSF51735 5 164 1.78E-14 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_2c01350 797b76f184e80aa85e6a50b7890f9f0d 276 Pfam PF16896 Phosphogluconate dehydrogenase (decarboxylating) C-term 128 276 1.5E-68 T 12-10-2018 IPR031663 Phosphogluconate dehydrogenase (decarboxylating) , C-terminal VAPA_1c40550 4e7e1a9932df300979dbb7cdaac022c2 227 SUPERFAMILY SSF48008 84 219 6.8E-22 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal VAPA_1c40550 4e7e1a9932df300979dbb7cdaac022c2 227 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 51 67 2.0E-6 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_1c40550 4e7e1a9932df300979dbb7cdaac022c2 227 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 37 51 2.0E-6 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_1c40550 4e7e1a9932df300979dbb7cdaac022c2 227 Pfam PF07729 FCD domain 88 210 5.6E-22 T 12-10-2018 IPR011711 GntR, C-terminal VAPA_1c40550 4e7e1a9932df300979dbb7cdaac022c2 227 Pfam PF00392 Bacterial regulatory proteins, gntR family 15 77 3.2E-21 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_1c40550 4e7e1a9932df300979dbb7cdaac022c2 227 Gene3D G3DSA:1.20.120.530 81 218 7.4E-27 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal VAPA_1c40550 4e7e1a9932df300979dbb7cdaac022c2 227 SMART SM00895 87 212 1.3E-18 T 12-10-2018 IPR011711 GntR, C-terminal VAPA_1c40550 4e7e1a9932df300979dbb7cdaac022c2 227 Gene3D G3DSA:1.10.10.10 4 77 5.6E-23 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c40550 4e7e1a9932df300979dbb7cdaac022c2 227 SMART SM00345 19 77 9.6E-21 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_1c40550 4e7e1a9932df300979dbb7cdaac022c2 227 SUPERFAMILY SSF46785 11 104 2.11E-21 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c23830 1101d057079c82a3105f58b32a308bb4 397 Gene3D G3DSA:3.90.1150.10 260 397 5.4E-34 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 VAPA_1c23830 1101d057079c82a3105f58b32a308bb4 397 Gene3D G3DSA:3.40.640.10 1 257 9.7E-63 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 VAPA_1c23830 1101d057079c82a3105f58b32a308bb4 397 PIRSF PIRSF001434 1 397 2.3E-107 T 12-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 VAPA_1c23830 1101d057079c82a3105f58b32a308bb4 397 SUPERFAMILY SSF53383 16 395 1.01E-87 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase VAPA_1c23830 1101d057079c82a3105f58b32a308bb4 397 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 6 394 1.3E-79 T 12-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 VAPA_1c47840 ac8968b3eff9d00536fe0569f1fdf9fa 298 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 27 51 - T 12-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 VAPA_1c47840 ac8968b3eff9d00536fe0569f1fdf9fa 298 TIGRFAM TIGR02152 D_ribokin_bact: ribokinase 1 286 2.8E-92 T 12-10-2018 IPR011877 Ribokinase GO:0004747|GO:0006014 KEGG: 00030+2.7.1.15|Reactome: R-HSA-71336 VAPA_1c47840 ac8968b3eff9d00536fe0569f1fdf9fa 298 SUPERFAMILY SSF53613 1 284 2.34E-76 T 12-10-2018 IPR029056 Ribokinase-like VAPA_1c47840 ac8968b3eff9d00536fe0569f1fdf9fa 298 PRINTS PR00990 Ribokinase signature 161 176 2.4E-18 T 12-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 VAPA_1c47840 ac8968b3eff9d00536fe0569f1fdf9fa 298 PRINTS PR00990 Ribokinase signature 22 41 2.4E-18 T 12-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 VAPA_1c47840 ac8968b3eff9d00536fe0569f1fdf9fa 298 PRINTS PR00990 Ribokinase signature 94 107 2.4E-18 T 12-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 VAPA_1c47840 ac8968b3eff9d00536fe0569f1fdf9fa 298 PRINTS PR00990 Ribokinase signature 205 216 2.4E-18 T 12-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 VAPA_1c47840 ac8968b3eff9d00536fe0569f1fdf9fa 298 Gene3D G3DSA:3.40.1190.20 1 289 2.7E-92 T 12-10-2018 IPR029056 Ribokinase-like VAPA_1c47840 ac8968b3eff9d00536fe0569f1fdf9fa 298 Hamap MF_01987 Ribokinase [rbsK]. 1 289 22.44 T 12-10-2018 IPR011877 Ribokinase GO:0004747|GO:0006014 KEGG: 00030+2.7.1.15|Reactome: R-HSA-71336 VAPA_1c47840 ac8968b3eff9d00536fe0569f1fdf9fa 298 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 234 247 - T 12-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 VAPA_1c47840 ac8968b3eff9d00536fe0569f1fdf9fa 298 Pfam PF00294 pfkB family carbohydrate kinase 9 282 8.2E-64 T 12-10-2018 IPR011611 Carbohydrate kinase PfkB VAPA_1c26410 acf00cfcbff9c27d264995ed3cd27f76 308 SUPERFAMILY SSF46785 14 96 1.86E-19 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c26410 acf00cfcbff9c27d264995ed3cd27f76 308 Pfam PF03466 LysR substrate binding domain 105 305 1.1E-32 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_1c26410 acf00cfcbff9c27d264995ed3cd27f76 308 Gene3D G3DSA:3.40.190.10 172 275 2.3E-52 T 12-10-2018 VAPA_1c26410 acf00cfcbff9c27d264995ed3cd27f76 308 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 19 76 4.9E-18 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c26410 acf00cfcbff9c27d264995ed3cd27f76 308 Gene3D G3DSA:1.10.10.10 17 104 1.5E-22 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c26410 acf00cfcbff9c27d264995ed3cd27f76 308 SUPERFAMILY SSF53850 105 307 3.8E-36 T 12-10-2018 VAPA_1c26410 acf00cfcbff9c27d264995ed3cd27f76 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 53 64 2.1E-5 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c26410 acf00cfcbff9c27d264995ed3cd27f76 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 32 43 2.1E-5 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c26410 acf00cfcbff9c27d264995ed3cd27f76 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 43 53 2.1E-5 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c26410 acf00cfcbff9c27d264995ed3cd27f76 308 Gene3D G3DSA:3.40.190.10 112 301 2.3E-52 T 12-10-2018 VAPA_1c12790 cf8edbdc766b77adfda2bf46f370ed12 438 Pfam PF01168 Alanine racemase, N-terminal domain 59 268 6.8E-15 T 12-10-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 VAPA_1c12790 cf8edbdc766b77adfda2bf46f370ed12 438 Gene3D G3DSA:3.20.20.10 60 299 5.3E-131 T 12-10-2018 IPR029066 PLP-binding barrel VAPA_1c12790 cf8edbdc766b77adfda2bf46f370ed12 438 SUPERFAMILY SSF51419 59 274 1.53E-26 T 12-10-2018 IPR029066 PLP-binding barrel VAPA_1c12790 cf8edbdc766b77adfda2bf46f370ed12 438 Gene3D G3DSA:2.40.37.20 41 438 5.3E-131 T 12-10-2018 VAPA_1c12790 cf8edbdc766b77adfda2bf46f370ed12 438 Pfam PF14031 Putative serine dehydratase domain 323 424 4.3E-19 T 12-10-2018 IPR026956 D-serine dehydratase-like domain VAPA_1c12790 cf8edbdc766b77adfda2bf46f370ed12 438 SMART SM01119 323 425 9.4E-43 T 12-10-2018 IPR026956 D-serine dehydratase-like domain VAPA_1c09660 db978b4e0cccca9c477dccbfbf61a2b7 582 Pfam PF03717 Penicillin-binding Protein dimerisation domain 66 216 5.5E-21 T 12-10-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 VAPA_1c09660 db978b4e0cccca9c477dccbfbf61a2b7 582 Gene3D G3DSA:3.90.1310.30 59 233 1.1E-48 T 12-10-2018 VAPA_1c09660 db978b4e0cccca9c477dccbfbf61a2b7 582 Hamap MF_02080 Peptidoglycan D,D-transpeptidase FtsI [ftsI]. 18 570 41.745 T 12-10-2018 IPR037532 Peptidoglycan D,D-transpeptidase FtsI GO:0005887|GO:0008658|GO:0008955|GO:0009252|GO:0051301 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 VAPA_1c09660 db978b4e0cccca9c477dccbfbf61a2b7 582 Gene3D G3DSA:3.30.450.330 234 559 1.6E-107 T 12-10-2018 VAPA_1c09660 db978b4e0cccca9c477dccbfbf61a2b7 582 SUPERFAMILY SSF56519 62 232 4.45E-45 T 12-10-2018 IPR036138 Penicillin-binding protein, dimerisation domain superfamily GO:0008658 VAPA_1c09660 db978b4e0cccca9c477dccbfbf61a2b7 582 Gene3D G3DSA:3.40.710.10 294 476 1.6E-107 T 12-10-2018 VAPA_1c09660 db978b4e0cccca9c477dccbfbf61a2b7 582 Pfam PF00905 Penicillin binding protein transpeptidase domain 258 554 5.3E-74 T 12-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 VAPA_1c09660 db978b4e0cccca9c477dccbfbf61a2b7 582 SUPERFAMILY SSF56601 185 567 1.56E-88 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like VAPA_2c13160 b9ff20773a120aa7f79bedc67d5bea1c 223 Gene3D G3DSA:2.60.120.10 119 219 6.3E-16 T 12-10-2018 IPR014710 RmlC-like jelly roll fold VAPA_2c13160 b9ff20773a120aa7f79bedc67d5bea1c 223 Pfam PF07883 Cupin domain 149 217 1.8E-11 T 12-10-2018 IPR013096 Cupin 2, conserved barrel VAPA_2c13160 b9ff20773a120aa7f79bedc67d5bea1c 223 Pfam PF13560 Helix-turn-helix domain 41 97 1.0E-11 T 12-10-2018 VAPA_2c13160 b9ff20773a120aa7f79bedc67d5bea1c 223 SMART SM00530 45 100 3.3E-12 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 VAPA_2c13160 b9ff20773a120aa7f79bedc67d5bea1c 223 Gene3D G3DSA:1.10.260.40 38 109 5.2E-16 T 12-10-2018 VAPA_2c13160 b9ff20773a120aa7f79bedc67d5bea1c 223 SUPERFAMILY SSF47413 40 104 1.63E-15 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 VAPA_2c13160 b9ff20773a120aa7f79bedc67d5bea1c 223 SUPERFAMILY SSF51182 93 219 1.65E-22 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily VAPA_1c04220 9afe215c9621b78d7fd291f48ab71a2f 329 Gene3D G3DSA:3.40.190.150 32 319 1.8E-86 T 12-10-2018 VAPA_1c04220 9afe215c9621b78d7fd291f48ab71a2f 329 SUPERFAMILY SSF53850 117 298 5.86E-9 T 12-10-2018 VAPA_1c04220 9afe215c9621b78d7fd291f48ab71a2f 329 Gene3D G3DSA:3.40.190.10 130 254 1.8E-86 T 12-10-2018 VAPA_1c04220 9afe215c9621b78d7fd291f48ab71a2f 329 PIRSF PIRSF017082 1 328 2.5E-65 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c04220 9afe215c9621b78d7fd291f48ab71a2f 329 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 52 324 9.3E-60 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c18920 c765079b8f21c1e1824723ba5f6922a3 137 Gene3D G3DSA:3.30.420.270 62 130 1.3E-14 T 12-10-2018 VAPA_1c18920 c765079b8f21c1e1824723ba5f6922a3 137 Pfam PF02472 Biopolymer transport protein ExbD/TolR 13 134 9.7E-31 T 12-10-2018 IPR003400 Biopolymer transport protein ExbD/TolR GO:0022857|GO:0055085 VAPA_1c11300 92a1c97a534359a57933b7a8bb385410 403 Pfam PF12693 GspL periplasmic domain 258 365 4.2E-8 T 12-10-2018 IPR025691 GspL periplasmic domain VAPA_1c11300 92a1c97a534359a57933b7a8bb385410 403 Pfam PF05134 Type II secretion system (T2SS), protein L 34 139 7.3E-12 T 12-10-2018 IPR024230 GspL, cytoplasmic actin-ATPase-like domain VAPA_1c11300 92a1c97a534359a57933b7a8bb385410 403 SUPERFAMILY SSF53067 10 143 5.44E-23 T 12-10-2018 VAPA_1c11300 92a1c97a534359a57933b7a8bb385410 403 Gene3D G3DSA:3.30.420.380 11 158 1.4E-18 T 12-10-2018 VAPA_1c39690 0061d8ec0d61e5e87f6affc66bc26bf6 321 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 9 180 3.2E-43 T 12-10-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain VAPA_1c39690 0061d8ec0d61e5e87f6affc66bc26bf6 321 Pfam PF07683 Cobalamin synthesis protein cobW C-terminal domain 231 319 1.5E-7 T 12-10-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal VAPA_1c39690 0061d8ec0d61e5e87f6affc66bc26bf6 321 Gene3D G3DSA:3.40.50.300 5 200 1.2E-52 T 12-10-2018 VAPA_1c39690 0061d8ec0d61e5e87f6affc66bc26bf6 321 SUPERFAMILY SSF52540 6 176 1.79E-28 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c41260 415e37c66cb24ca1c8ba56755224a461 336 PIRSF PIRSF017082 1 336 1.1E-82 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c41260 415e37c66cb24ca1c8ba56755224a461 336 Gene3D G3DSA:3.40.190.10 138 261 4.9E-108 T 12-10-2018 VAPA_1c41260 415e37c66cb24ca1c8ba56755224a461 336 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 60 329 1.9E-82 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c41260 415e37c66cb24ca1c8ba56755224a461 336 SUPERFAMILY SSF53850 125 297 3.85E-18 T 12-10-2018 VAPA_1c41260 415e37c66cb24ca1c8ba56755224a461 336 Gene3D G3DSA:3.40.190.150 40 326 4.9E-108 T 12-10-2018 VAPA_1c23110 b3e433a7bf86b219926c6b44acc0efe4 178 SUPERFAMILY SSF46785 2 133 3.38E-36 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c23110 b3e433a7bf86b219926c6b44acc0efe4 178 Pfam PF02082 Transcriptional regulator 1 82 6.0E-27 T 12-10-2018 IPR000944 Transcription regulator Rrf2-type VAPA_1c23110 b3e433a7bf86b219926c6b44acc0efe4 178 Gene3D G3DSA:1.10.10.10 1 143 5.0E-50 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c23110 b3e433a7bf86b219926c6b44acc0efe4 178 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 1 131 4.8E-44 T 12-10-2018 IPR000944 Transcription regulator Rrf2-type VAPA_1c23110 b3e433a7bf86b219926c6b44acc0efe4 178 TIGRFAM TIGR02010 IscR: iron-sulfur cluster assembly transcription factor IscR 1 134 6.2E-64 T 12-10-2018 IPR010242 Transcription factor HTH, IscR GO:0003690|GO:0003700|GO:0006355 VAPA_1c21170 57106330d53d144ef7baad13b39b1597 173 SUPERFAMILY SSF47413 5 53 4.79E-11 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 VAPA_1c21170 57106330d53d144ef7baad13b39b1597 173 SUPERFAMILY SSF51182 45 169 1.14E-20 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily VAPA_1c21170 57106330d53d144ef7baad13b39b1597 173 Pfam PF01381 Helix-turn-helix 9 43 4.4E-9 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 VAPA_1c21170 57106330d53d144ef7baad13b39b1597 173 Gene3D G3DSA:1.10.260.40 2 59 8.2E-12 T 12-10-2018 VAPA_1c21170 57106330d53d144ef7baad13b39b1597 173 SMART SM00530 1 50 0.0056 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 VAPA_1c21170 57106330d53d144ef7baad13b39b1597 173 Pfam PF07883 Cupin domain 99 167 5.1E-11 T 12-10-2018 IPR013096 Cupin 2, conserved barrel VAPA_1c21170 57106330d53d144ef7baad13b39b1597 173 Gene3D G3DSA:2.60.120.10 68 169 1.1E-16 T 12-10-2018 IPR014710 RmlC-like jelly roll fold VAPA_1c13150 c202369d0911b8fbed30b2882d7133c2 598 Pfam PF05157 Type II secretion system (T2SS), protein E, N-terminal domain 75 174 1.6E-14 T 12-10-2018 IPR007831 General secretory system II, protein E, N-terminal VAPA_1c13150 c202369d0911b8fbed30b2882d7133c2 598 Pfam PF00437 Type II/IV secretion system protein 225 485 1.3E-73 T 12-10-2018 IPR001482 Type II/IV secretion system protein VAPA_1c13150 c202369d0911b8fbed30b2882d7133c2 598 SMART SM00382 346 467 8.9E-5 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c13150 c202369d0911b8fbed30b2882d7133c2 598 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 413 427 - T 12-10-2018 IPR001482 Type II/IV secretion system protein VAPA_1c13150 c202369d0911b8fbed30b2882d7133c2 598 SUPERFAMILY SSF52540 207 592 5.89E-92 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c13150 c202369d0911b8fbed30b2882d7133c2 598 SUPERFAMILY SSF160246 23 169 1.19E-12 T 12-10-2018 IPR037257 General secretory system II, protein E, N-terminal superfamily VAPA_1c13150 c202369d0911b8fbed30b2882d7133c2 598 Gene3D G3DSA:3.30.450.90 188 318 5.6E-39 T 12-10-2018 VAPA_1c13150 c202369d0911b8fbed30b2882d7133c2 598 Gene3D G3DSA:3.40.50.300 321 595 1.6E-100 T 12-10-2018 VAPA_2c11470 6f77cb3f5f1d4bb3cd63a0ceb87d7a57 330 TIGRFAM TIGR00787 dctP: TRAP transporter solute receptor, DctP family 31 284 4.5E-73 T 12-10-2018 IPR004682 TRAP transporter solute receptor, DctP family GO:0030288|GO:0055085 VAPA_2c11470 6f77cb3f5f1d4bb3cd63a0ceb87d7a57 330 PIRSF PIRSF006470 1 326 1.5E-84 T 12-10-2018 IPR004682 TRAP transporter solute receptor, DctP family GO:0030288|GO:0055085 VAPA_2c11470 6f77cb3f5f1d4bb3cd63a0ceb87d7a57 330 Gene3D G3DSA:3.40.190.170 26 329 1.9E-93 T 12-10-2018 IPR038404 TRAP transporter solute receptor DctP superfamily VAPA_2c11470 6f77cb3f5f1d4bb3cd63a0ceb87d7a57 330 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 31 306 1.3E-82 T 12-10-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0030288|GO:0055085 VAPA_1c54440 411eae49eebe7bd13dba2d4c5dd68498 323 Gene3D G3DSA:1.10.3720.10 88 317 1.9E-26 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c54440 411eae49eebe7bd13dba2d4c5dd68498 323 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 117 322 8.3E-47 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 VAPA_1c54440 411eae49eebe7bd13dba2d4c5dd68498 323 SUPERFAMILY SSF161098 95 308 9.81E-21 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c48780 220cfa3ba7ff7103ab5dbcac518ad9e9 390 PIRSF PIRSF016578 12 99 7.2E-5 T 12-10-2018 VAPA_1c48780 220cfa3ba7ff7103ab5dbcac518ad9e9 390 PIRSF PIRSF016578 135 390 1.2E-11 T 12-10-2018 VAPA_1c48780 220cfa3ba7ff7103ab5dbcac518ad9e9 390 SUPERFAMILY SSF56645 6 247 1.26E-82 T 12-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 VAPA_1c48780 220cfa3ba7ff7103ab5dbcac518ad9e9 390 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 127 222 2.0E-23 T 12-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 VAPA_1c48780 220cfa3ba7ff7103ab5dbcac518ad9e9 390 SUPERFAMILY SSF47203 232 387 5.32E-44 T 12-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 VAPA_1c48780 220cfa3ba7ff7103ab5dbcac518ad9e9 390 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 16 123 4.4E-35 T 12-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 VAPA_1c48780 220cfa3ba7ff7103ab5dbcac518ad9e9 390 Gene3D G3DSA:2.40.110.10 126 239 1.3E-43 T 12-10-2018 VAPA_1c48780 220cfa3ba7ff7103ab5dbcac518ad9e9 390 Gene3D G3DSA:1.20.140.10 240 390 4.2E-44 T 12-10-2018 VAPA_1c48780 220cfa3ba7ff7103ab5dbcac518ad9e9 390 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 129 141 - T 12-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 VAPA_1c48780 220cfa3ba7ff7103ab5dbcac518ad9e9 390 Gene3D G3DSA:1.10.540.10 1 125 1.7E-45 T 12-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 VAPA_1c48780 220cfa3ba7ff7103ab5dbcac518ad9e9 390 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 344 363 - T 12-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 VAPA_1c48780 220cfa3ba7ff7103ab5dbcac518ad9e9 390 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 234 385 5.9E-40 T 12-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 VAPA_1c21430 f2287478b4e16eedebffcd03792a8d87 583 Pfam PF07167 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus 95 261 1.6E-65 T 12-10-2018 IPR010941 Poly-beta-hydroxybutyrate polymerase, N-terminal domain GO:0042619 VAPA_1c21430 f2287478b4e16eedebffcd03792a8d87 583 Gene3D G3DSA:3.40.50.1820 253 511 7.8E-11 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c21430 f2287478b4e16eedebffcd03792a8d87 583 TIGRFAM TIGR01838 PHA_synth_I: poly(R)-hydroxyalkanoic acid synthase, class I 63 580 2.0E-212 T 12-10-2018 IPR010963 Poly(R)-hydroxyalkanoic acid synthase, class I GO:0005737|GO:0016746|GO:0042619 VAPA_1c21430 f2287478b4e16eedebffcd03792a8d87 583 SUPERFAMILY SSF53474 234 517 4.48E-43 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_2c03030 7143aca80eadb9dbb54c4a91ab2df13f 153 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 32 51 4.0E-10 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 VAPA_2c03030 7143aca80eadb9dbb54c4a91ab2df13f 153 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 21 32 4.0E-10 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 VAPA_2c03030 7143aca80eadb9dbb54c4a91ab2df13f 153 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 5 21 4.0E-10 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 VAPA_2c03030 7143aca80eadb9dbb54c4a91ab2df13f 153 SMART SM00344 5 111 1.9E-24 T 12-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 VAPA_2c03030 7143aca80eadb9dbb54c4a91ab2df13f 153 Pfam PF13404 AsnC-type helix-turn-helix domain 5 46 7.3E-13 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 VAPA_2c03030 7143aca80eadb9dbb54c4a91ab2df13f 153 Gene3D G3DSA:3.30.70.920 60 148 2.8E-16 T 12-10-2018 VAPA_2c03030 7143aca80eadb9dbb54c4a91ab2df13f 153 SUPERFAMILY SSF46785 4 60 1.57E-12 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_2c03030 7143aca80eadb9dbb54c4a91ab2df13f 153 Pfam PF01037 Lrp/AsnC ligand binding domain 74 141 6.0E-15 T 12-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain VAPA_2c03030 7143aca80eadb9dbb54c4a91ab2df13f 153 Gene3D G3DSA:1.10.10.10 2 56 8.4E-16 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_2c03030 7143aca80eadb9dbb54c4a91ab2df13f 153 SUPERFAMILY SSF54909 67 146 2.82E-15 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel VAPA_1c14740 ae5cc9406195923fad2cad8ad56434a3 123 SUPERFAMILY SSF50022 8 112 1.31E-18 T 12-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 VAPA_1c14740 ae5cc9406195923fad2cad8ad56434a3 123 Gene3D G3DSA:2.102.10.10 9 117 3.2E-11 T 12-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 VAPA_1c14740 ae5cc9406195923fad2cad8ad56434a3 123 Pfam PF00355 Rieske [2Fe-2S] domain 8 98 3.5E-9 T 12-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 VAPA_1c25880 e6774251af7deee097e9a13c9ce20c5b 304 Gene3D G3DSA:1.10.10.10 2 89 3.0E-25 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c25880 e6774251af7deee097e9a13c9ce20c5b 304 SUPERFAMILY SSF46785 3 87 4.61E-20 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c25880 e6774251af7deee097e9a13c9ce20c5b 304 SUPERFAMILY SSF53850 89 299 5.58E-42 T 12-10-2018 VAPA_1c25880 e6774251af7deee097e9a13c9ce20c5b 304 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 63 2.3E-18 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c25880 e6774251af7deee097e9a13c9ce20c5b 304 Gene3D G3DSA:3.40.190.290 91 296 5.6E-57 T 12-10-2018 VAPA_1c25880 e6774251af7deee097e9a13c9ce20c5b 304 Pfam PF03466 LysR substrate binding domain 89 296 5.2E-42 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_2c00570 88df6a44b260a6121e5f7ac5aa72b1f1 88 SUPERFAMILY SSF46689 16 77 7.17E-10 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 VAPA_2c00570 88df6a44b260a6121e5f7ac5aa72b1f1 88 Pfam PF13551 Winged helix-turn helix 19 74 6.4E-14 T 12-10-2018 VAPA_2c04850 42fbbf52cbd3d54430715ef41a8f22fe 317 Gene3D G3DSA:3.40.50.2020 20 155 5.6E-72 T 12-10-2018 VAPA_2c04850 42fbbf52cbd3d54430715ef41a8f22fe 317 SUPERFAMILY SSF53271 13 167 6.28E-35 T 12-10-2018 IPR029057 Phosphoribosyltransferase-like VAPA_2c04850 42fbbf52cbd3d54430715ef41a8f22fe 317 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 14 294 3.7E-56 T 12-10-2018 IPR005946 Ribose-phosphate pyrophosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 VAPA_2c04850 42fbbf52cbd3d54430715ef41a8f22fe 317 SMART SM01400 12 127 1.8E-35 T 12-10-2018 VAPA_2c04850 42fbbf52cbd3d54430715ef41a8f22fe 317 Pfam PF00156 Phosphoribosyl transferase domain 160 280 6.2E-13 T 12-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 VAPA_2c04850 42fbbf52cbd3d54430715ef41a8f22fe 317 SUPERFAMILY SSF53271 168 289 7.47E-24 T 12-10-2018 IPR029057 Phosphoribosyltransferase-like VAPA_2c04850 42fbbf52cbd3d54430715ef41a8f22fe 317 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 14 120 1.5E-20 T 12-10-2018 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 VAPA_2c04850 42fbbf52cbd3d54430715ef41a8f22fe 317 Gene3D G3DSA:3.40.50.2020 156 281 5.6E-72 T 12-10-2018 VAPA_1c03170 e48b79a36267b537241f9effd5e7d817 568 Pfam PF13450 NAD(P)-binding Rossmann-like domain 12 66 6.3E-7 T 12-10-2018 VAPA_1c03170 e48b79a36267b537241f9effd5e7d817 568 Gene3D G3DSA:3.50.50.60 4 388 2.5E-80 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c03170 e48b79a36267b537241f9effd5e7d817 568 Pfam PF04820 Tryptophan halogenase 110 374 1.0E-8 T 12-10-2018 IPR006905 Flavin-dependent halogenase VAPA_1c03170 e48b79a36267b537241f9effd5e7d817 568 SUPERFAMILY SSF51905 6 411 2.68E-27 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_2c11750 aa8c71ab6c005c36a15b71611c45a8a4 551 Gene3D G3DSA:1.10.3720.10 292 545 6.1E-37 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_2c11750 aa8c71ab6c005c36a15b71611c45a8a4 551 Gene3D G3DSA:1.10.3720.10 10 281 2.1E-54 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_2c11750 aa8c71ab6c005c36a15b71611c45a8a4 551 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 363 542 1.2E-9 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 VAPA_2c11750 aa8c71ab6c005c36a15b71611c45a8a4 551 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 86 254 5.5E-10 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 VAPA_2c11750 aa8c71ab6c005c36a15b71611c45a8a4 551 SUPERFAMILY SSF161098 292 544 1.5E-38 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_2c11750 aa8c71ab6c005c36a15b71611c45a8a4 551 SUPERFAMILY SSF161098 6 272 1.74E-45 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c14040 49fc3d1aa8b630942f5f1ae4b49afe8b 324 Gene3D G3DSA:3.40.190.150 25 314 5.4E-96 T 12-10-2018 VAPA_1c14040 49fc3d1aa8b630942f5f1ae4b49afe8b 324 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 42 320 5.8E-68 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c14040 49fc3d1aa8b630942f5f1ae4b49afe8b 324 PIRSF PIRSF017082 1 324 1.2E-67 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c14040 49fc3d1aa8b630942f5f1ae4b49afe8b 324 Gene3D G3DSA:3.40.190.10 121 246 5.4E-96 T 12-10-2018 VAPA_1c14040 49fc3d1aa8b630942f5f1ae4b49afe8b 324 SUPERFAMILY SSF53850 110 281 3.98E-10 T 12-10-2018 VAPA_1c50070 cb988365c3c826d150ab87bb847edfdc 150 SUPERFAMILY SSF54427 17 133 1.76E-32 T 12-10-2018 IPR032710 NTF2-like domain superfamily VAPA_1c50070 cb988365c3c826d150ab87bb847edfdc 150 Pfam PF13474 SnoaL-like domain 21 133 1.7E-17 T 12-10-2018 IPR037401 SnoaL-like domain VAPA_1c50070 cb988365c3c826d150ab87bb847edfdc 150 Gene3D G3DSA:3.10.450.50 10 150 1.3E-38 T 12-10-2018 VAPA_1c51060 0061c5877c1c58c38af0839aab36b809 371 Pfam PF04892 VanZ like family 23 131 6.3E-11 T 12-10-2018 IPR006976 VanZ-like VAPA_1c37140 4af73d6c0e363024e0247e473fbf5bd7 290 Gene3D G3DSA:1.10.3720.10 78 282 3.6E-17 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c37140 4af73d6c0e363024e0247e473fbf5bd7 290 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 105 287 1.1E-23 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 VAPA_1c37140 4af73d6c0e363024e0247e473fbf5bd7 290 SUPERFAMILY SSF161098 80 268 3.66E-24 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c13330 cd1ad422a738e9fe14a26e418bacad43 336 Gene3D G3DSA:3.40.50.2300 55 302 8.5E-70 T 12-10-2018 VAPA_1c13330 cd1ad422a738e9fe14a26e418bacad43 336 Pfam PF13377 Periplasmic binding protein-like domain 166 312 2.6E-30 T 12-10-2018 VAPA_1c13330 cd1ad422a738e9fe14a26e418bacad43 336 SMART SM00354 1 70 4.2E-24 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 VAPA_1c13330 cd1ad422a738e9fe14a26e418bacad43 336 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 47 1.2E-14 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 VAPA_1c13330 cd1ad422a738e9fe14a26e418bacad43 336 Gene3D G3DSA:1.10.260.40 1 54 1.8E-20 T 12-10-2018 VAPA_1c13330 cd1ad422a738e9fe14a26e418bacad43 336 SUPERFAMILY SSF53822 57 308 2.72E-61 T 12-10-2018 IPR028082 Periplasmic binding protein-like I VAPA_1c13330 cd1ad422a738e9fe14a26e418bacad43 336 SUPERFAMILY SSF47413 2 58 4.31E-15 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 VAPA_1c13330 cd1ad422a738e9fe14a26e418bacad43 336 Gene3D G3DSA:3.40.50.2300 158 285 8.5E-70 T 12-10-2018 VAPA_1c07050 afa1192781eb04de268dc8cd44c2b140 304 SUPERFAMILY SSF53850 90 296 7.91E-41 T 12-10-2018 VAPA_1c07050 afa1192781eb04de268dc8cd44c2b140 304 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 67 1.7E-13 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c07050 afa1192781eb04de268dc8cd44c2b140 304 Pfam PF03466 LysR substrate binding domain 98 294 8.5E-22 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_1c07050 afa1192781eb04de268dc8cd44c2b140 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 44 1.7E-5 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c07050 afa1192781eb04de268dc8cd44c2b140 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 44 55 1.7E-5 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c07050 afa1192781eb04de268dc8cd44c2b140 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 23 34 1.7E-5 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c07050 afa1192781eb04de268dc8cd44c2b140 304 Gene3D G3DSA:3.40.190.10 92 293 6.5E-69 T 12-10-2018 VAPA_1c07050 afa1192781eb04de268dc8cd44c2b140 304 Gene3D G3DSA:3.40.190.10 171 269 6.5E-69 T 12-10-2018 VAPA_1c07050 afa1192781eb04de268dc8cd44c2b140 304 SUPERFAMILY SSF46785 3 85 7.71E-17 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c07050 afa1192781eb04de268dc8cd44c2b140 304 Gene3D G3DSA:1.10.10.10 1 88 1.9E-28 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c07820 052a403d5e84e81bea6d81c28267b1b0 370 SUPERFAMILY SSF51726 5 365 1.08E-106 T 12-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 VAPA_1c07820 052a403d5e84e81bea6d81c28267b1b0 370 ProSitePatterns PS00907 Uroporphyrinogen decarboxylase signature 2. 143 159 - T 12-10-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 VAPA_1c07820 052a403d5e84e81bea6d81c28267b1b0 370 ProSitePatterns PS00906 Uroporphyrinogen decarboxylase signature 1. 24 33 - T 12-10-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 VAPA_1c07820 052a403d5e84e81bea6d81c28267b1b0 370 TIGRFAM TIGR01464 hemE: uroporphyrinogen decarboxylase 11 361 2.0E-118 T 12-10-2018 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 VAPA_1c07820 052a403d5e84e81bea6d81c28267b1b0 370 Pfam PF01208 Uroporphyrinogen decarboxylase (URO-D) 7 362 8.1E-128 T 12-10-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 VAPA_1c07820 052a403d5e84e81bea6d81c28267b1b0 370 Gene3D G3DSA:3.20.20.210 2 370 4.7E-141 T 12-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 VAPA_1c07820 052a403d5e84e81bea6d81c28267b1b0 370 Hamap MF_00218 Uroporphyrinogen decarboxylase [hemE]. 8 364 46.718 T 12-10-2018 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 VAPA_1c42170 4066f359208ad10b528d1eed0aa0f539 716 Pfam PF12838 4Fe-4S dicluster domain 320 364 1.5E-9 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain VAPA_1c42170 4066f359208ad10b528d1eed0aa0f539 716 Pfam PF00037 4Fe-4S binding domain 192 212 5.3E-5 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain VAPA_1c42170 4066f359208ad10b528d1eed0aa0f539 716 Pfam PF13187 4Fe-4S dicluster domain 587 633 4.4E-7 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain VAPA_1c42170 4066f359208ad10b528d1eed0aa0f539 716 Gene3D G3DSA:3.30.70.20 192 239 8.3E-6 T 12-10-2018 VAPA_1c42170 4066f359208ad10b528d1eed0aa0f539 716 Gene3D G3DSA:3.30.70.20 575 636 3.3E-11 T 12-10-2018 VAPA_1c42170 4066f359208ad10b528d1eed0aa0f539 716 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 618 629 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site VAPA_1c42170 4066f359208ad10b528d1eed0aa0f539 716 Gene3D G3DSA:3.30.70.20 313 382 1.2E-13 T 12-10-2018 VAPA_1c42170 4066f359208ad10b528d1eed0aa0f539 716 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 350 361 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site VAPA_1c42170 4066f359208ad10b528d1eed0aa0f539 716 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 197 208 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site VAPA_1c42170 4066f359208ad10b528d1eed0aa0f539 716 SUPERFAMILY SSF54862 192 678 2.19E-59 T 12-10-2018 VAPA_1c09140 9b3cdad3001ed662018694bc57f14c22 304 SUPERFAMILY SSF161098 99 286 1.57E-23 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c09140 9b3cdad3001ed662018694bc57f14c22 304 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 29 70 1.5E-9 T 12-10-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain VAPA_1c09140 9b3cdad3001ed662018694bc57f14c22 304 Gene3D G3DSA:1.10.3720.10 94 303 3.8E-18 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c09140 9b3cdad3001ed662018694bc57f14c22 304 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 122 301 1.2E-22 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 VAPA_1c30890 423a471527a551dbe8b60f86adbafc7d 393 SUPERFAMILY SSF53748 3 390 7.89E-135 T 12-10-2018 IPR036043 Phosphoglycerate kinase superfamily GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 VAPA_1c30890 423a471527a551dbe8b60f86adbafc7d 393 Pfam PF00162 Phosphoglycerate kinase 7 380 3.8E-131 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 VAPA_1c30890 423a471527a551dbe8b60f86adbafc7d 393 Gene3D G3DSA:3.40.50.1260 8 388 1.5E-137 T 12-10-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 VAPA_1c30890 423a471527a551dbe8b60f86adbafc7d 393 PRINTS PR00477 Phosphoglycerate kinase family signature 310 335 5.8E-77 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 VAPA_1c30890 423a471527a551dbe8b60f86adbafc7d 393 PRINTS PR00477 Phosphoglycerate kinase family signature 32 54 5.8E-77 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 VAPA_1c30890 423a471527a551dbe8b60f86adbafc7d 393 PRINTS PR00477 Phosphoglycerate kinase family signature 134 156 5.8E-77 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 VAPA_1c30890 423a471527a551dbe8b60f86adbafc7d 393 PRINTS PR00477 Phosphoglycerate kinase family signature 165 187 5.8E-77 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 VAPA_1c30890 423a471527a551dbe8b60f86adbafc7d 393 PRINTS PR00477 Phosphoglycerate kinase family signature 366 383 5.8E-77 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 VAPA_1c30890 423a471527a551dbe8b60f86adbafc7d 393 PRINTS PR00477 Phosphoglycerate kinase family signature 10 26 5.8E-77 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 VAPA_1c30890 423a471527a551dbe8b60f86adbafc7d 393 PRINTS PR00477 Phosphoglycerate kinase family signature 106 121 5.8E-77 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 VAPA_1c30890 423a471527a551dbe8b60f86adbafc7d 393 PRINTS PR00477 Phosphoglycerate kinase family signature 188 207 5.8E-77 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 VAPA_1c30890 423a471527a551dbe8b60f86adbafc7d 393 PRINTS PR00477 Phosphoglycerate kinase family signature 343 354 5.8E-77 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 VAPA_1c30890 423a471527a551dbe8b60f86adbafc7d 393 Hamap MF_00145 Phosphoglycerate kinase [pgk]. 5 390 37.372 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 VAPA_1c30890 423a471527a551dbe8b60f86adbafc7d 393 PIRSF PIRSF000724 1 393 4.8E-127 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 VAPA_1c30890 423a471527a551dbe8b60f86adbafc7d 393 ProSitePatterns PS00111 Phosphoglycerate kinase signature. 15 25 - T 12-10-2018 IPR015911 Phosphoglycerate kinase, conserved site GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 VAPA_1c30890 423a471527a551dbe8b60f86adbafc7d 393 Gene3D G3DSA:3.40.50.1260 167 380 1.5E-137 T 12-10-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 VAPA_2c04290 dc040899063b3feeaa080b473c9db82a 356 Pfam PF09587 Bacterial capsule synthesis protein PGA_cap 24 275 2.6E-65 T 12-10-2018 IPR019079 Capsule synthesis protein, CapA VAPA_2c04290 dc040899063b3feeaa080b473c9db82a 356 SUPERFAMILY SSF56300 52 293 4.39E-29 T 12-10-2018 VAPA_2c04290 dc040899063b3feeaa080b473c9db82a 356 SMART SM00854 1 275 4.4E-85 T 12-10-2018 IPR019079 Capsule synthesis protein, CapA VAPA_2c10550 f8c1366a336cf67160e5fd283c28cee3 102 Pfam PF14542 GCN5-related N-acetyl-transferase 15 91 1.5E-21 T 12-10-2018 IPR031165 Yjdj-type Gcn5-related N-acetyltransferase VAPA_2c10550 f8c1366a336cf67160e5fd283c28cee3 102 SUPERFAMILY SSF55729 7 93 4.18E-24 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase VAPA_2c10550 f8c1366a336cf67160e5fd283c28cee3 102 Gene3D G3DSA:3.40.630.30 1 98 1.4E-23 T 12-10-2018 VAPA_1c43150 e47f37dbc04f935ffbb10c23954bfce2 202 Hamap MF_01891 Flagellar transcriptional regulator FlhC [flhC]. 1 187 45.215 T 12-10-2018 IPR007944 Flagellar transcriptional activator FlhC GO:0003677|GO:0045893|GO:1902208 VAPA_1c43150 e47f37dbc04f935ffbb10c23954bfce2 202 SUPERFAMILY SSF160930 5 160 7.59E-59 T 12-10-2018 VAPA_1c43150 e47f37dbc04f935ffbb10c23954bfce2 202 ProDom PD016592 ACTIVATOR TRANSCRIPTIONAL FLAGELLUM FLAGELLAR TRANSCRIPTION FLHC RNA DNA-BINDING REGULATION DNA-DIRECTED 1 164 2.0E-60 T 12-10-2018 IPR007944 Flagellar transcriptional activator FlhC GO:0003677|GO:0045893|GO:1902208 VAPA_1c43150 e47f37dbc04f935ffbb10c23954bfce2 202 PIRSF PIRSF003159 1 181 8.7E-83 T 12-10-2018 IPR007944 Flagellar transcriptional activator FlhC GO:0003677|GO:0045893|GO:1902208 VAPA_1c43150 e47f37dbc04f935ffbb10c23954bfce2 202 Pfam PF05280 Flagellar transcriptional activator (FlhC) 1 171 3.6E-80 T 12-10-2018 IPR007944 Flagellar transcriptional activator FlhC GO:0003677|GO:0045893|GO:1902208 VAPA_1c03760 e9f7b8ea073b1a627fc502f250374c81 301 Gene3D G3DSA:3.40.190.10 30 271 1.0E-82 T 12-10-2018 VAPA_1c03760 e9f7b8ea073b1a627fc502f250374c81 301 SUPERFAMILY SSF53850 7 268 4.89E-57 T 12-10-2018 VAPA_1c03760 e9f7b8ea073b1a627fc502f250374c81 301 SMART SM00062 40 268 1.9E-43 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF VAPA_1c03760 e9f7b8ea073b1a627fc502f250374c81 301 Gene3D G3DSA:3.40.190.10 130 225 1.0E-82 T 12-10-2018 VAPA_1c03760 e9f7b8ea073b1a627fc502f250374c81 301 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 43 266 9.7E-46 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF VAPA_1c21320 b09f30bcf498ecd0d70a78ef92ff3304 259 ProSitePatterns PS00708 Prolyl endopeptidase family serine active site. 85 115 - T 12-10-2018 IPR002471 Peptidase S9, serine active site GO:0004252|GO:0006508 VAPA_1c21320 b09f30bcf498ecd0d70a78ef92ff3304 259 Pfam PF00326 Prolyl oligopeptidase family 52 240 8.7E-13 T 12-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 VAPA_1c21320 b09f30bcf498ecd0d70a78ef92ff3304 259 Gene3D G3DSA:3.40.50.1820 30 242 4.2E-52 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c21320 b09f30bcf498ecd0d70a78ef92ff3304 259 SUPERFAMILY SSF53474 9 239 3.35E-39 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c13560 cdac3086fdde21902f696a73d0e6dd68 399 Pfam PF02653 Branched-chain amino acid transport system / permease component 34 339 1.8E-46 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 VAPA_1c42110 dd4d7366d141ccf8dfc248967681d7a8 406 TIGRFAM TIGR01583 formate-DH-gamm: formate dehydrogenase, gamma subunit 173 375 9.7E-49 T 12-10-2018 IPR006471 Formate dehydrogenase, gamma subunit GO:0008863|GO:0009326|GO:0016021|GO:0045333 VAPA_1c42110 dd4d7366d141ccf8dfc248967681d7a8 406 Gene3D G3DSA:1.20.950.20 169 385 1.5E-60 T 12-10-2018 VAPA_1c42110 dd4d7366d141ccf8dfc248967681d7a8 406 Pfam PF01292 Prokaryotic cytochrome b561 176 357 2.2E-19 T 12-10-2018 IPR011577 Cytochrome b561, bacterial/Ni-hydrogenase GO:0009055|GO:0016021 VAPA_1c42110 dd4d7366d141ccf8dfc248967681d7a8 406 SUPERFAMILY SSF81342 170 384 3.61E-44 T 12-10-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 VAPA_2c01470 42cda13c2df8d7c18019a2f795403700 326 Gene3D G3DSA:3.40.190.150 29 316 1.1E-84 T 12-10-2018 VAPA_2c01470 42cda13c2df8d7c18019a2f795403700 326 Gene3D G3DSA:3.40.190.10 127 251 1.1E-84 T 12-10-2018 VAPA_2c01470 42cda13c2df8d7c18019a2f795403700 326 SUPERFAMILY SSF53850 115 293 2.17E-5 T 12-10-2018 VAPA_2c01470 42cda13c2df8d7c18019a2f795403700 326 PIRSF PIRSF017082 1 325 2.1E-60 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_2c01470 42cda13c2df8d7c18019a2f795403700 326 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 48 321 4.8E-62 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_2c04500 c4908a8f57ae10e3253abfc8ccbca391 294 ProSitePatterns PS01096 PpiC-type peptidyl-prolyl cis-trans isomerase signature. 173 193 - T 12-10-2018 IPR023058 Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site Reactome: R-HSA-1169408|Reactome: R-HSA-6804756|Reactome: R-HSA-6811555|Reactome: R-HSA-936440 VAPA_2c04500 c4908a8f57ae10e3253abfc8ccbca391 294 Pfam PF00639 PPIC-type PPIASE domain 138 236 7.8E-13 T 12-10-2018 IPR000297 Peptidyl-prolyl cis-trans isomerase, PpiC-type GO:0003755 VAPA_2c04500 c4908a8f57ae10e3253abfc8ccbca391 294 Gene3D G3DSA:1.10.4030.30 96 253 7.1E-20 T 12-10-2018 VAPA_2c04500 c4908a8f57ae10e3253abfc8ccbca391 294 Gene3D G3DSA:3.10.50.40 132 240 7.1E-20 T 12-10-2018 VAPA_2c04500 c4908a8f57ae10e3253abfc8ccbca391 294 SUPERFAMILY SSF54534 128 241 7.2E-18 T 12-10-2018 VAPA_1c11540 0d8715ca5ebff2bbef9001fb8747983d 753 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 256 443 8.9E-16 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 VAPA_1c11540 0d8715ca5ebff2bbef9001fb8747983d 753 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 556 733 6.7E-14 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 VAPA_1c11540 0d8715ca5ebff2bbef9001fb8747983d 753 Gene3D G3DSA:1.10.3720.10 174 459 5.4E-57 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c11540 0d8715ca5ebff2bbef9001fb8747983d 753 Gene3D G3DSA:1.10.3720.10 476 740 5.5E-45 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c11540 0d8715ca5ebff2bbef9001fb8747983d 753 SUPERFAMILY SSF161098 176 452 1.83E-46 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c11540 0d8715ca5ebff2bbef9001fb8747983d 753 SUPERFAMILY SSF161098 479 735 2.22E-42 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c27110 57bd187af2cfa001f3fe0f79c7c9cace 1361 SMART SM00869 1086 1346 1.2E-28 T 12-10-2018 IPR005546 Autotransporter beta-domain VAPA_1c27110 57bd187af2cfa001f3fe0f79c7c9cace 1361 Pfam PF13018 Extended Signal Peptide of Type V secretion system 1 23 3.2E-9 T 12-10-2018 IPR024973 ESPR domain VAPA_1c27110 57bd187af2cfa001f3fe0f79c7c9cace 1361 TIGRFAM TIGR02601 autotrns_rpt: autotransporter-associated beta strand repeat 821 851 2.7E-13 T 12-10-2018 IPR013425 Autotransporter-associated beta strand repeat VAPA_1c27110 57bd187af2cfa001f3fe0f79c7c9cace 1361 TIGRFAM TIGR02601 autotrns_rpt: autotransporter-associated beta strand repeat 485 515 8.7E-9 T 12-10-2018 IPR013425 Autotransporter-associated beta strand repeat VAPA_1c27110 57bd187af2cfa001f3fe0f79c7c9cace 1361 TIGRFAM TIGR02601 autotrns_rpt: autotransporter-associated beta strand repeat 730 761 6.5E-9 T 12-10-2018 IPR013425 Autotransporter-associated beta strand repeat VAPA_1c27110 57bd187af2cfa001f3fe0f79c7c9cace 1361 TIGRFAM TIGR01414 autotrans_barl: outer membrane autotransporter barrel domain 895 1361 6.6E-59 T 12-10-2018 IPR006315 Outer membrane autotransporter barrel GO:0019867 VAPA_1c27110 57bd187af2cfa001f3fe0f79c7c9cace 1361 SUPERFAMILY SSF51126 462 779 2.54E-14 T 12-10-2018 IPR011050 Pectin lyase fold/virulence factor VAPA_1c27110 57bd187af2cfa001f3fe0f79c7c9cace 1361 SUPERFAMILY SSF51126 764 1013 1.19E-33 T 12-10-2018 IPR011050 Pectin lyase fold/virulence factor VAPA_1c27110 57bd187af2cfa001f3fe0f79c7c9cace 1361 Pfam PF03797 Autotransporter beta-domain 1089 1335 4.1E-38 T 12-10-2018 IPR005546 Autotransporter beta-domain VAPA_1c27110 57bd187af2cfa001f3fe0f79c7c9cace 1361 Gene3D G3DSA:2.160.20.20 844 1014 2.5E-36 T 12-10-2018 IPR012332 P22 tailspike-like, C-terminal domain superfamily VAPA_1c27110 57bd187af2cfa001f3fe0f79c7c9cace 1361 Gene3D G3DSA:2.40.128.130 1040 1361 2.7E-61 T 12-10-2018 IPR036709 Autotransporter beta-domain superfamily VAPA_1c27110 57bd187af2cfa001f3fe0f79c7c9cace 1361 Pfam PF12951 Passenger-associated-transport-repeat 486 513 1.6E-6 T 12-10-2018 IPR013425 Autotransporter-associated beta strand repeat VAPA_1c27110 57bd187af2cfa001f3fe0f79c7c9cace 1361 Pfam PF12951 Passenger-associated-transport-repeat 397 425 0.0053 T 12-10-2018 IPR013425 Autotransporter-associated beta strand repeat VAPA_1c27110 57bd187af2cfa001f3fe0f79c7c9cace 1361 Pfam PF12951 Passenger-associated-transport-repeat 821 849 2.2E-11 T 12-10-2018 IPR013425 Autotransporter-associated beta strand repeat VAPA_1c27110 57bd187af2cfa001f3fe0f79c7c9cace 1361 Pfam PF12951 Passenger-associated-transport-repeat 731 759 9.9E-9 T 12-10-2018 IPR013425 Autotransporter-associated beta strand repeat VAPA_1c27110 57bd187af2cfa001f3fe0f79c7c9cace 1361 SUPERFAMILY SSF103515 1048 1361 2.48E-36 T 12-10-2018 IPR036709 Autotransporter beta-domain superfamily VAPA_1c11480 99900f48490110f00707c0ae1f643161 332 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 243 307 1.9E-19 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 VAPA_1c11480 99900f48490110f00707c0ae1f643161 332 Pfam PF00005 ABC transporter 39 192 2.9E-33 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c11480 99900f48490110f00707c0ae1f643161 332 Gene3D G3DSA:3.40.50.300 28 331 2.6E-99 T 12-10-2018 VAPA_1c11480 99900f48490110f00707c0ae1f643161 332 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 242 325 8.8E-28 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 VAPA_1c11480 99900f48490110f00707c0ae1f643161 332 SUPERFAMILY SSF52540 33 263 2.39E-70 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c11480 99900f48490110f00707c0ae1f643161 332 SMART SM00382 47 241 1.6E-16 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c11480 99900f48490110f00707c0ae1f643161 332 ProSitePatterns PS00211 ABC transporters family signature. 164 178 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_1c50260 8959faf9cf46cd1094aaec614570db38 272 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 87 260 9.6E-17 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 VAPA_1c50260 8959faf9cf46cd1094aaec614570db38 272 Gene3D G3DSA:1.10.3720.10 13 269 1.3E-59 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c50260 8959faf9cf46cd1094aaec614570db38 272 SUPERFAMILY SSF161098 15 262 3.01E-54 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_2c11520 d2ef3cfda970570d894a2c78ba2e1ec0 241 PIRSF PIRSF033328 13 241 1.9E-47 T 12-10-2018 IPR009389 Protein of unknown function DUF1045 KEGG: 00030+2.7.4.23|MetaCyc: PWY-7805|MetaCyc: PWY-7807 VAPA_2c11520 d2ef3cfda970570d894a2c78ba2e1ec0 241 Pfam PF06299 Protein of unknown function (DUF1045) 73 232 3.3E-49 T 12-10-2018 IPR009389 Protein of unknown function DUF1045 KEGG: 00030+2.7.4.23|MetaCyc: PWY-7805|MetaCyc: PWY-7807 VAPA_1c26600 9b8608a9e091795dd9c5f965c361e664 210 Pfam PF04403 Paraquat-inducible protein A 47 196 8.9E-45 T 12-10-2018 IPR007498 Intermembrane transport protein PqiA-like VAPA_1c02960 0f2a8007b5e5e6bf196c8525588cd14a 287 Gene3D G3DSA:3.40.830.10 1 285 2.0E-74 T 12-10-2018 VAPA_1c02960 0f2a8007b5e5e6bf196c8525588cd14a 287 Pfam PF02900 Catalytic LigB subunit of aromatic ring-opening dioxygenase 7 280 1.3E-61 T 12-10-2018 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 VAPA_1c02960 0f2a8007b5e5e6bf196c8525588cd14a 287 SUPERFAMILY SSF53213 12 280 1.7E-51 T 12-10-2018 VAPA_1c02960 0f2a8007b5e5e6bf196c8525588cd14a 287 TIGRFAM TIGR02298 HpaD_Fe: 3,4-dihydroxyphenylacetate 2,3-dioxygenase 1 282 7.4E-144 T 12-10-2018 IPR011984 3,4-dihydroxyphenylacetate 2,3-dioxygenase GO:0008687 KEGG: 00350+1.13.11.15 VAPA_1c29720 36a1fedf14663d0f49d94004687fc03e 243 SMART SM00862 161 237 1.5E-24 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 VAPA_1c29720 36a1fedf14663d0f49d94004687fc03e 243 SUPERFAMILY SSF46894 137 239 9.92E-28 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 VAPA_1c29720 36a1fedf14663d0f49d94004687fc03e 243 Gene3D G3DSA:1.10.10.10 135 243 1.3E-35 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c29720 36a1fedf14663d0f49d94004687fc03e 243 Pfam PF00486 Transcriptional regulatory protein, C terminal 161 237 6.7E-23 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 VAPA_1c29720 36a1fedf14663d0f49d94004687fc03e 243 Pfam PF00072 Response regulator receiver domain 11 120 1.3E-31 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_1c29720 36a1fedf14663d0f49d94004687fc03e 243 SUPERFAMILY SSF52172 8 131 9.53E-43 T 12-10-2018 IPR011006 CheY-like superfamily VAPA_1c29720 36a1fedf14663d0f49d94004687fc03e 243 SMART SM00448 9 120 7.9E-44 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_1c29720 36a1fedf14663d0f49d94004687fc03e 243 Gene3D G3DSA:3.40.50.2300 6 134 1.7E-39 T 12-10-2018 VAPA_1c52200 13aefb1a9b388c8080f755bb05161139 691 SUPERFAMILY SSF56935 12 690 5.5E-109 T 12-10-2018 VAPA_1c52200 13aefb1a9b388c8080f755bb05161139 691 Gene3D G3DSA:2.170.130.10 32 157 1.2E-27 T 12-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily VAPA_1c52200 13aefb1a9b388c8080f755bb05161139 691 Gene3D G3DSA:2.40.170.20 158 690 1.6E-84 T 12-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily VAPA_1c52200 13aefb1a9b388c8080f755bb05161139 691 Pfam PF07715 TonB-dependent Receptor Plug Domain 48 147 4.3E-19 T 12-10-2018 IPR012910 TonB-dependent receptor, plug domain VAPA_1c52200 13aefb1a9b388c8080f755bb05161139 691 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 49 690 2.6E-103 T 12-10-2018 IPR010105 TonB-dependent siderophore receptor GO:0005506|GO:0015891|GO:0038023 VAPA_1c52200 13aefb1a9b388c8080f755bb05161139 691 Pfam PF00593 TonB dependent receptor 271 689 6.1E-35 T 12-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel VAPA_1c33330 cb0d5566a86b5d28457e81c20225f12a 145 Pfam PF13560 Helix-turn-helix domain 83 141 3.6E-9 T 12-10-2018 VAPA_1c33330 cb0d5566a86b5d28457e81c20225f12a 145 SMART SM00530 84 139 1.0E-4 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 VAPA_1c33330 cb0d5566a86b5d28457e81c20225f12a 145 Gene3D G3DSA:1.10.260.40 80 135 2.0E-10 T 12-10-2018 VAPA_1c33330 cb0d5566a86b5d28457e81c20225f12a 145 SUPERFAMILY SSF47413 82 135 2.95E-8 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 VAPA_1c50540 ee3df11bc66d01dec3c234e0034eca63 291 Gene3D G3DSA:1.10.287.80 6 284 6.3E-104 T 12-10-2018 VAPA_1c50540 ee3df11bc66d01dec3c234e0034eca63 291 TIGRFAM TIGR01146 ATPsyn_F1gamma: ATP synthase F1, gamma subunit 1 287 1.5E-101 T 12-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 VAPA_1c50540 ee3df11bc66d01dec3c234e0034eca63 291 Gene3D G3DSA:3.40.1380.10 61 207 6.3E-104 T 12-10-2018 VAPA_1c50540 ee3df11bc66d01dec3c234e0034eca63 291 PRINTS PR00126 ATP synthase gamma subunit signature 166 183 7.3E-35 T 12-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 VAPA_1c50540 ee3df11bc66d01dec3c234e0034eca63 291 PRINTS PR00126 ATP synthase gamma subunit signature 266 287 7.3E-35 T 12-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 VAPA_1c50540 ee3df11bc66d01dec3c234e0034eca63 291 PRINTS PR00126 ATP synthase gamma subunit signature 73 92 7.3E-35 T 12-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 VAPA_1c50540 ee3df11bc66d01dec3c234e0034eca63 291 PRINTS PR00126 ATP synthase gamma subunit signature 235 254 7.3E-35 T 12-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 VAPA_1c50540 ee3df11bc66d01dec3c234e0034eca63 291 ProSitePatterns PS00153 ATP synthase gamma subunit signature. 274 287 - T 12-10-2018 IPR023632 ATP synthase, F1 complex, gamma subunit conserved site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 VAPA_1c50540 ee3df11bc66d01dec3c234e0034eca63 291 SUPERFAMILY SSF52943 4 287 1.31E-90 T 12-10-2018 IPR035968 ATP synthase, F1 complex, gamma subunit superfamily GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 VAPA_1c50540 ee3df11bc66d01dec3c234e0034eca63 291 Hamap MF_00815 ATP synthase gamma chain [atpG]. 1 288 34.535 T 12-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 VAPA_1c50540 ee3df11bc66d01dec3c234e0034eca63 291 Pfam PF00231 ATP synthase 5 287 5.6E-93 T 12-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 VAPA_1c41730 4b0e25db2aef6935277cc4d5b991857c 200 Pfam PF00196 Bacterial regulatory proteins, luxR family 136 191 1.3E-17 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_1c41730 4b0e25db2aef6935277cc4d5b991857c 200 ProSitePatterns PS00622 LuxR-type HTH domain signature. 151 178 - T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_1c41730 4b0e25db2aef6935277cc4d5b991857c 200 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 167 179 8.8E-11 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_1c41730 4b0e25db2aef6935277cc4d5b991857c 200 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 137 151 8.8E-11 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_1c41730 4b0e25db2aef6935277cc4d5b991857c 200 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 151 167 8.8E-11 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_1c41730 4b0e25db2aef6935277cc4d5b991857c 200 Gene3D G3DSA:3.40.50.2300 1 123 1.6E-19 T 12-10-2018 VAPA_1c41730 4b0e25db2aef6935277cc4d5b991857c 200 SUPERFAMILY SSF46894 126 197 3.4E-19 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 VAPA_1c41730 4b0e25db2aef6935277cc4d5b991857c 200 SUPERFAMILY SSF52172 1 119 4.55E-19 T 12-10-2018 IPR011006 CheY-like superfamily VAPA_1c41730 4b0e25db2aef6935277cc4d5b991857c 200 SMART SM00421 134 191 4.0E-18 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_1c41730 4b0e25db2aef6935277cc4d5b991857c 200 Pfam PF00072 Response regulator receiver domain 3 115 1.6E-15 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_1c41730 4b0e25db2aef6935277cc4d5b991857c 200 Gene3D G3DSA:1.10.10.10 127 199 6.0E-20 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c41730 4b0e25db2aef6935277cc4d5b991857c 200 SMART SM00448 1 115 1.2E-9 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_1c18190 1a252d75632aaac2db4c8825ac628004 328 PIRSF PIRSF017082 1 328 6.6E-86 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c18190 1a252d75632aaac2db4c8825ac628004 328 Gene3D G3DSA:3.40.190.150 33 318 8.8E-110 T 12-10-2018 VAPA_1c18190 1a252d75632aaac2db4c8825ac628004 328 Gene3D G3DSA:3.40.190.10 130 253 8.8E-110 T 12-10-2018 VAPA_1c18190 1a252d75632aaac2db4c8825ac628004 328 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 51 323 4.4E-87 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c18190 1a252d75632aaac2db4c8825ac628004 328 SUPERFAMILY SSF53850 114 289 1.28E-14 T 12-10-2018 VAPA_1c50870 0f822fb7db3d734dd81848225ff304a6 83 ProSitePatterns PS00579 Ribosomal protein L29 signature. 54 68 - T 12-10-2018 IPR018254 Ribosomal protein L29, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VAPA_1c50870 0f822fb7db3d734dd81848225ff304a6 83 Hamap MF_00374 50S ribosomal protein L29 [rpmC]. 16 75 15.578 T 12-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VAPA_1c50870 0f822fb7db3d734dd81848225ff304a6 83 Pfam PF00831 Ribosomal L29 protein 20 75 2.6E-18 T 12-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VAPA_1c50870 0f822fb7db3d734dd81848225ff304a6 83 TIGRFAM TIGR00012 L29: ribosomal protein uL29 21 75 9.8E-17 T 12-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VAPA_1c50870 0f822fb7db3d734dd81848225ff304a6 83 Gene3D G3DSA:1.10.287.310 17 77 3.6E-20 T 12-10-2018 VAPA_1c50870 0f822fb7db3d734dd81848225ff304a6 83 SUPERFAMILY SSF46561 16 78 3.92E-17 T 12-10-2018 IPR036049 Ribosomal protein L29/L35 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VAPA_1c29380 d31eaf77fe3122f47c65e42980c70357 264 Gene3D G3DSA:3.40.1280.10 112 262 1.8E-40 T 12-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal VAPA_1c29380 d31eaf77fe3122f47c65e42980c70357 264 Pfam PF00588 SpoU rRNA Methylase family 117 252 1.7E-28 T 12-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 VAPA_1c29380 d31eaf77fe3122f47c65e42980c70357 264 Gene3D G3DSA:3.30.1330.30 8 107 1.4E-7 T 12-10-2018 IPR029064 50S ribosomal protein L30e-like VAPA_1c29380 d31eaf77fe3122f47c65e42980c70357 264 SUPERFAMILY SSF75217 116 253 6.54E-33 T 12-10-2018 IPR029028 Alpha/beta knot methyltransferases VAPA_1c29380 d31eaf77fe3122f47c65e42980c70357 264 SUPERFAMILY SSF55315 9 99 7.53E-13 T 12-10-2018 IPR029064 50S ribosomal protein L30e-like VAPA_2c03450 1c3cb606e297c2fe17dadca09f50ee61 217 Pfam PF04972 BON domain 78 146 4.4E-14 T 12-10-2018 IPR007055 BON domain VAPA_2c03450 1c3cb606e297c2fe17dadca09f50ee61 217 Pfam PF04972 BON domain 3 70 1.2E-17 T 12-10-2018 IPR007055 BON domain VAPA_2c03450 1c3cb606e297c2fe17dadca09f50ee61 217 Pfam PF04972 BON domain 151 216 1.8E-10 T 12-10-2018 IPR007055 BON domain VAPA_2c03450 1c3cb606e297c2fe17dadca09f50ee61 217 SMART SM00749 8 71 7.8E-5 T 12-10-2018 IPR014004 Transport-associated and nodulation domain, bacteria VAPA_2c03450 1c3cb606e297c2fe17dadca09f50ee61 217 SMART SM00749 154 217 0.006 T 12-10-2018 IPR014004 Transport-associated and nodulation domain, bacteria VAPA_2c03450 1c3cb606e297c2fe17dadca09f50ee61 217 SMART SM00749 83 146 69.0 T 12-10-2018 IPR014004 Transport-associated and nodulation domain, bacteria VAPA_2c03450 1c3cb606e297c2fe17dadca09f50ee61 217 Gene3D G3DSA:3.40.1520.20 104 211 8.4E-6 T 12-10-2018 VAPA_1c09870 14502ca3b135bbe4ab38870bfed9fe1c 285 SUPERFAMILY SSF53223 1 107 4.6E-24 T 12-10-2018 VAPA_1c09870 14502ca3b135bbe4ab38870bfed9fe1c 285 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 123 203 3.6E-9 T 12-10-2018 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase VAPA_1c09870 14502ca3b135bbe4ab38870bfed9fe1c 285 Hamap MF_00222 Shikimate dehydrogenase (NADP(+)) [aroE]. 1 280 28.281 T 12-10-2018 IPR022893 Shikimate dehydrogenase family GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 VAPA_1c09870 14502ca3b135bbe4ab38870bfed9fe1c 285 TIGRFAM TIGR00507 aroE: shikimate dehydrogenase 3 281 2.4E-66 T 12-10-2018 IPR011342 Shikimate dehydrogenase GO:0004764|GO:0019632|GO:0050661|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 VAPA_1c09870 14502ca3b135bbe4ab38870bfed9fe1c 285 Pfam PF08501 Shikimate dehydrogenase substrate binding domain 6 94 6.4E-17 T 12-10-2018 IPR013708 Shikimate dehydrogenase substrate binding, N-terminal GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 VAPA_1c09870 14502ca3b135bbe4ab38870bfed9fe1c 285 SUPERFAMILY SSF51735 108 278 1.47E-39 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c09870 14502ca3b135bbe4ab38870bfed9fe1c 285 Gene3D G3DSA:3.40.50.720 122 247 8.5E-67 T 12-10-2018 VAPA_1c09870 14502ca3b135bbe4ab38870bfed9fe1c 285 Gene3D G3DSA:3.40.50.10860 6 268 8.5E-67 T 12-10-2018 VAPA_1c48980 dab7f2289d2a1f0a52e724140677f670 301 SUPERFAMILY SSF55681 3 281 1.79E-134 T 12-10-2018 VAPA_1c48980 dab7f2289d2a1f0a52e724140677f670 301 TIGRFAM TIGR00388 glyQ: glycine--tRNA ligase, alpha subunit 3 288 3.5E-158 T 12-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 VAPA_1c48980 dab7f2289d2a1f0a52e724140677f670 301 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 77 97 5.3E-69 T 12-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 VAPA_1c48980 dab7f2289d2a1f0a52e724140677f670 301 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 108 132 5.3E-69 T 12-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 VAPA_1c48980 dab7f2289d2a1f0a52e724140677f670 301 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 157 172 5.3E-69 T 12-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 VAPA_1c48980 dab7f2289d2a1f0a52e724140677f670 301 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 242 258 5.3E-69 T 12-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 VAPA_1c48980 dab7f2289d2a1f0a52e724140677f670 301 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 56 71 5.3E-69 T 12-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 VAPA_1c48980 dab7f2289d2a1f0a52e724140677f670 301 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 134 154 5.3E-69 T 12-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 VAPA_1c48980 dab7f2289d2a1f0a52e724140677f670 301 Gene3D G3DSA:3.30.930.10 1 205 1.2E-112 T 12-10-2018 VAPA_1c48980 dab7f2289d2a1f0a52e724140677f670 301 Gene3D G3DSA:1.20.58.180 206 287 3.7E-34 T 12-10-2018 VAPA_1c48980 dab7f2289d2a1f0a52e724140677f670 301 Pfam PF02091 Glycyl-tRNA synthetase alpha subunit 4 281 1.9E-151 T 12-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 VAPA_1c48980 dab7f2289d2a1f0a52e724140677f670 301 Hamap MF_00254 Glycine--tRNA ligase alpha subunit [glyQ]. 2 282 60.323 T 12-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 VAPA_1c25910 1f9492fb704ad6a7f127ee1272b42647 338 TIGRFAM TIGR00971 3a0106s03: sulfate ABC transporter, sulfate-binding protein 19 332 1.8E-117 T 12-10-2018 IPR005669 Thiosulphate/Sulfate-binding protein GO:0008272|GO:0015419 VAPA_1c25910 1f9492fb704ad6a7f127ee1272b42647 338 Gene3D G3DSA:3.40.190.10 34 301 8.7E-118 T 12-10-2018 VAPA_1c25910 1f9492fb704ad6a7f127ee1272b42647 338 SUPERFAMILY SSF53850 27 334 1.73E-77 T 12-10-2018 VAPA_1c25910 1f9492fb704ad6a7f127ee1272b42647 338 Pfam PF13531 Bacterial extracellular solute-binding protein 49 283 2.9E-41 T 12-10-2018 VAPA_1c25910 1f9492fb704ad6a7f127ee1272b42647 338 Gene3D G3DSA:3.40.190.10 121 331 8.7E-118 T 12-10-2018 VAPA_1c54270 9f586d9776b0f0545f3831998c8c7f58 83 SUPERFAMILY SSF54292 8 82 1.84E-15 T 12-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 VAPA_1c54270 9f586d9776b0f0545f3831998c8c7f58 83 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 7 82 2.4E-20 T 12-10-2018 VAPA_1c54270 9f586d9776b0f0545f3831998c8c7f58 83 Gene3D G3DSA:3.10.20.440 5 83 7.7E-10 T 12-10-2018 VAPA_1c20920 6e7794ff4670c47f3c0f97dc1da85126 107 Gene3D G3DSA:1.10.10.10 1 93 1.4E-18 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c20920 6e7794ff4670c47f3c0f97dc1da85126 107 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 10 25 5.2E-8 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 VAPA_1c20920 6e7794ff4670c47f3c0f97dc1da85126 107 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 60 75 5.2E-8 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 VAPA_1c20920 6e7794ff4670c47f3c0f97dc1da85126 107 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 45 60 5.2E-8 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 VAPA_1c20920 6e7794ff4670c47f3c0f97dc1da85126 107 Pfam PF12840 Helix-turn-helix domain 10 69 2.0E-14 T 12-10-2018 VAPA_1c20920 6e7794ff4670c47f3c0f97dc1da85126 107 SUPERFAMILY SSF46785 2 94 5.64E-21 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c20920 6e7794ff4670c47f3c0f97dc1da85126 107 SMART SM00418 8 89 6.8E-11 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 VAPA_1c25930 3530dc89499bc5048ffcd0ddda502beb 300 SUPERFAMILY SSF161098 20 271 4.06E-56 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c25930 3530dc89499bc5048ffcd0ddda502beb 300 TIGRFAM TIGR00969 3a0106s02: sulfate ABC transporter, permease protein 19 278 1.6E-102 T 12-10-2018 IPR005667 Sulphate ABC transporter permease protein 2 GO:0008272|GO:0015419|GO:0016020 VAPA_1c25930 3530dc89499bc5048ffcd0ddda502beb 300 TIGRFAM TIGR02140 permease_CysW: sulfate ABC transporter, permease protein CysW 21 280 7.1E-130 T 12-10-2018 IPR011866 Sulphate ABC transporter, permease protein CysW GO:0008272|GO:0015116|GO:0016021 VAPA_1c25930 3530dc89499bc5048ffcd0ddda502beb 300 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 84 269 2.8E-14 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 VAPA_1c25930 3530dc89499bc5048ffcd0ddda502beb 300 Gene3D G3DSA:1.10.3720.10 23 282 2.4E-65 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c51990 c50a2f3f2f6f665346fa384aaddeec92 441 SUPERFAMILY SSF53822 30 402 5.3E-56 T 12-10-2018 IPR028082 Periplasmic binding protein-like I VAPA_1c51990 c50a2f3f2f6f665346fa384aaddeec92 441 Gene3D G3DSA:3.40.50.2300 148 290 4.9E-80 T 12-10-2018 VAPA_1c51990 c50a2f3f2f6f665346fa384aaddeec92 441 Gene3D G3DSA:3.40.50.2300 38 362 4.9E-80 T 12-10-2018 VAPA_1c51990 c50a2f3f2f6f665346fa384aaddeec92 441 Pfam PF13458 Periplasmic binding protein 29 398 1.5E-84 T 12-10-2018 IPR028081 Leucine-binding protein domain VAPA_1c20970 78b76cbbec4bd8188547f00c7e18ac31 397 SUPERFAMILY SSF103473 5 387 4.84E-32 T 12-10-2018 IPR036259 MFS transporter superfamily VAPA_1c20970 78b76cbbec4bd8188547f00c7e18ac31 397 Pfam PF07690 Major Facilitator Superfamily 21 336 3.9E-18 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 VAPA_1c20970 78b76cbbec4bd8188547f00c7e18ac31 397 Gene3D G3DSA:1.20.1250.20 1 388 8.3E-28 T 12-10-2018 VAPA_1c36740 074647e0cb6778304e035a65c2bcadb3 123 ProDom PD074011 PRECURSOR SIGNAL RESISTANCE CZCI ZINC COBALT-ZINC-CADMIUM SYSTEM COBALT CATION CADMIUM 1 75 4.0E-9 T 12-10-2018 IPR020487 Cobalt/zinc/cadmium resistance protein CzcI VAPA_1c36740 074647e0cb6778304e035a65c2bcadb3 123 Pfam PF11162 Protein of unknown function (DUF2946) 4 112 3.7E-5 T 12-10-2018 IPR021333 Protein of unknown function DUF2946 VAPA_1c22220 c9c963932ec4487bcfc322819e3743fb 270 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 145 164 4.1E-27 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c22220 c9c963932ec4487bcfc322819e3743fb 270 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 119 135 4.1E-27 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c22220 c9c963932ec4487bcfc322819e3743fb 270 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 166 183 4.1E-27 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c22220 c9c963932ec4487bcfc322819e3743fb 270 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 4.1E-27 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c22220 c9c963932ec4487bcfc322819e3743fb 270 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 72 83 4.1E-27 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c22220 c9c963932ec4487bcfc322819e3743fb 270 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 72 83 1.1E-11 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c22220 c9c963932ec4487bcfc322819e3743fb 270 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 145 164 1.1E-11 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c22220 c9c963932ec4487bcfc322819e3743fb 270 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 125 133 1.1E-11 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c22220 c9c963932ec4487bcfc322819e3743fb 270 Pfam PF00106 short chain dehydrogenase 6 187 5.7E-51 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c22220 c9c963932ec4487bcfc322819e3743fb 270 Gene3D G3DSA:3.40.50.720 2 248 3.5E-64 T 12-10-2018 VAPA_1c22220 c9c963932ec4487bcfc322819e3743fb 270 SUPERFAMILY SSF51735 5 257 4.17E-63 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c53120 7bde317747753fa442ade0ac8a31948f 1202 SUPERFAMILY SSF52518 471 659 4.58E-13 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold VAPA_1c53120 7bde317747753fa442ade0ac8a31948f 1202 SUPERFAMILY SSF53323 761 963 1.57E-26 T 12-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 VAPA_1c53120 7bde317747753fa442ade0ac8a31948f 1202 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 770 958 3.8E-20 T 12-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 VAPA_1c53120 7bde317747753fa442ade0ac8a31948f 1202 SUPERFAMILY SSF52518 30 207 2.35E-18 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold VAPA_1c53120 7bde317747753fa442ade0ac8a31948f 1202 Gene3D G3DSA:3.40.920.10 759 963 5.6E-17 T 12-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 VAPA_1c53120 7bde317747753fa442ade0ac8a31948f 1202 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 492 604 4.5E-6 T 12-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 VAPA_1c53120 7bde317747753fa442ade0ac8a31948f 1202 Gene3D G3DSA:3.40.50.970 22 235 1.5E-26 T 12-10-2018 VAPA_2c08870 96fb9e1233fe8c23e9260516f3f174de 295 Pfam PF03301 Tryptophan 2,3-dioxygenase 163 280 2.4E-13 T 12-10-2018 IPR004981 Tryptophan 2,3-dioxygenase GO:0004833|GO:0019441|GO:0020037 KEGG: 00380+1.13.11.11|Reactome: R-HSA-71240 VAPA_2c08870 96fb9e1233fe8c23e9260516f3f174de 295 Pfam PF03301 Tryptophan 2,3-dioxygenase 15 145 1.1E-14 T 12-10-2018 IPR004981 Tryptophan 2,3-dioxygenase GO:0004833|GO:0019441|GO:0020037 KEGG: 00380+1.13.11.11|Reactome: R-HSA-71240 VAPA_2c08870 96fb9e1233fe8c23e9260516f3f174de 295 Gene3D G3DSA:1.20.58.480 18 280 7.6E-60 T 12-10-2018 VAPA_2c08870 96fb9e1233fe8c23e9260516f3f174de 295 SUPERFAMILY SSF140959 19 280 3.01E-66 T 12-10-2018 IPR037217 Tryptophan/Indoleamine 2,3-dioxygenase-like GO:0019441|GO:0020037|GO:0046872 KEGG: 00380+1.13.11.11|Reactome: R-HSA-71240 VAPA_1c26130 35874fdbaebc5e214139f14d5256ffa1 1340 SUPERFAMILY SSF55326 238 435 5.23E-53 T 12-10-2018 IPR036921 PurM-like, N-terminal domain superfamily VAPA_1c26130 35874fdbaebc5e214139f14d5256ffa1 1340 SUPERFAMILY SSF56042 832 1070 1.38E-42 T 12-10-2018 IPR036676 PurM-like, C-terminal domain superfamily VAPA_1c26130 35874fdbaebc5e214139f14d5256ffa1 1340 SMART SM01211 1088 1339 1.5E-137 T 12-10-2018 VAPA_1c26130 35874fdbaebc5e214139f14d5256ffa1 1340 Pfam PF02769 AIR synthase related protein, C-terminal domain 443 596 5.8E-27 T 12-10-2018 IPR010918 PurM-like, C-terminal domain VAPA_1c26130 35874fdbaebc5e214139f14d5256ffa1 1340 Pfam PF02769 AIR synthase related protein, C-terminal domain 856 998 1.5E-12 T 12-10-2018 IPR010918 PurM-like, C-terminal domain VAPA_1c26130 35874fdbaebc5e214139f14d5256ffa1 1340 SUPERFAMILY SSF56042 443 666 2.39E-52 T 12-10-2018 IPR036676 PurM-like, C-terminal domain superfamily VAPA_1c26130 35874fdbaebc5e214139f14d5256ffa1 1340 Gene3D G3DSA:3.90.650.10 429 617 1.9E-54 T 12-10-2018 IPR036676 PurM-like, C-terminal domain superfamily VAPA_1c26130 35874fdbaebc5e214139f14d5256ffa1 1340 Gene3D G3DSA:3.30.1330.10 231 428 1.5E-40 T 12-10-2018 IPR036921 PurM-like, N-terminal domain superfamily VAPA_1c26130 35874fdbaebc5e214139f14d5256ffa1 1340 Gene3D G3DSA:1.10.8.750 171 230 7.0E-27 T 12-10-2018 VAPA_1c26130 35874fdbaebc5e214139f14d5256ffa1 1340 SUPERFAMILY SSF82697 13 168 2.25E-37 T 12-10-2018 IPR036604 Phosphoribosylformylglycinamidine synthase subunit PurS-like superfamily KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 VAPA_1c26130 35874fdbaebc5e214139f14d5256ffa1 1340 Gene3D G3DSA:3.30.1330.10 631 820 1.4E-23 T 12-10-2018 IPR036921 PurM-like, N-terminal domain superfamily VAPA_1c26130 35874fdbaebc5e214139f14d5256ffa1 1340 Gene3D G3DSA:3.40.50.880 1030 1340 6.7E-120 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like VAPA_1c26130 35874fdbaebc5e214139f14d5256ffa1 1340 Pfam PF13507 CobB/CobQ-like glutamine amidotransferase domain 1088 1339 1.6E-98 T 12-10-2018 VAPA_1c26130 35874fdbaebc5e214139f14d5256ffa1 1340 Gene3D G3DSA:3.90.650.10 821 1029 2.4E-28 T 12-10-2018 IPR036676 PurM-like, C-terminal domain superfamily VAPA_1c26130 35874fdbaebc5e214139f14d5256ffa1 1340 SUPERFAMILY SSF52317 1086 1339 3.99E-88 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like VAPA_1c26130 35874fdbaebc5e214139f14d5256ffa1 1340 Hamap MF_00419 Phosphoribosylformylglycinamidine synthase [purL]. 12 1340 20.067 T 12-10-2018 IPR010073 Phosphoribosylformylglycinamidine synthase GO:0004642|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 VAPA_1c26130 35874fdbaebc5e214139f14d5256ffa1 1340 SUPERFAMILY SSF55326 632 826 9.16E-66 T 12-10-2018 IPR036921 PurM-like, N-terminal domain superfamily VAPA_1c26130 35874fdbaebc5e214139f14d5256ffa1 1340 SUPERFAMILY SSF109736 172 237 8.11E-21 T 12-10-2018 VAPA_1c26130 35874fdbaebc5e214139f14d5256ffa1 1340 TIGRFAM TIGR01735 FGAM_synt: phosphoribosylformylglycinamidine synthase 15 1339 0.0 T 12-10-2018 IPR010073 Phosphoribosylformylglycinamidine synthase GO:0004642|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 VAPA_1c21490 799387d2f1a209c20b03d4e7530cf168 294 PIRSF PIRSF015582 2 292 1.4E-71 T 12-10-2018 IPR011206 Citrate lyase beta subunit-like VAPA_1c21490 799387d2f1a209c20b03d4e7530cf168 294 Gene3D G3DSA:3.20.20.60 2 284 2.0E-75 T 12-10-2018 VAPA_1c21490 799387d2f1a209c20b03d4e7530cf168 294 SUPERFAMILY SSF51621 6 232 2.51E-54 T 12-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 VAPA_1c21490 799387d2f1a209c20b03d4e7530cf168 294 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 9 223 6.5E-30 T 12-10-2018 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 VAPA_1c08650 fc1669a1740937af566c39fa439cba39 204 SUPERFAMILY SSF52499 9 203 9.42E-44 T 12-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 VAPA_1c08650 fc1669a1740937af566c39fa439cba39 204 Pfam PF00857 Isochorismatase family 12 196 3.6E-36 T 12-10-2018 IPR000868 Isochorismatase-like GO:0003824 VAPA_1c08650 fc1669a1740937af566c39fa439cba39 204 Gene3D G3DSA:3.40.50.850 2 204 2.2E-46 T 12-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 VAPA_2c00340 cba4896c6b05e4ec2bf90f76e9a58124 123 TIGRFAM TIGR01689 EcbF-BcbF: capsule biosynthesis phosphatase 1 123 1.8E-55 T 12-10-2018 IPR010039 Capsule biosynthesis phosphatase VAPA_2c00340 cba4896c6b05e4ec2bf90f76e9a58124 123 SUPERFAMILY SSF56784 2 104 7.85E-20 T 12-10-2018 IPR036412 HAD-like superfamily VAPA_2c00340 cba4896c6b05e4ec2bf90f76e9a58124 123 Gene3D G3DSA:3.40.50.1000 1 123 5.9E-37 T 12-10-2018 IPR023214 HAD superfamily VAPA_1c06770 4d3d181bf2fd7248cc0cf4890f7e94ca 249 SMART SM00448 1 110 0.0025 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_1c06770 4d3d181bf2fd7248cc0cf4890f7e94ca 249 Gene3D G3DSA:3.40.50.2300 1 116 4.5E-14 T 12-10-2018 VAPA_1c06770 4d3d181bf2fd7248cc0cf4890f7e94ca 249 Pfam PF00072 Response regulator receiver domain 17 109 7.1E-7 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_1c06770 4d3d181bf2fd7248cc0cf4890f7e94ca 249 SMART SM00862 143 218 6.4E-19 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 VAPA_1c06770 4d3d181bf2fd7248cc0cf4890f7e94ca 249 SUPERFAMILY SSF46894 121 219 2.64E-23 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 VAPA_1c06770 4d3d181bf2fd7248cc0cf4890f7e94ca 249 SUPERFAMILY SSF52172 8 113 1.71E-14 T 12-10-2018 IPR011006 CheY-like superfamily VAPA_1c06770 4d3d181bf2fd7248cc0cf4890f7e94ca 249 Gene3D G3DSA:1.10.10.10 117 222 5.6E-25 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c06770 4d3d181bf2fd7248cc0cf4890f7e94ca 249 Pfam PF00486 Transcriptional regulatory protein, C terminal 146 218 3.8E-21 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 VAPA_1c06930 5fd574b1237860b5b835c40f345da886 324 SUPERFAMILY SSF53850 115 288 1.9E-11 T 12-10-2018 VAPA_1c06930 5fd574b1237860b5b835c40f345da886 324 Gene3D G3DSA:3.40.190.10 126 249 2.3E-104 T 12-10-2018 VAPA_1c06930 5fd574b1237860b5b835c40f345da886 324 Gene3D G3DSA:3.40.190.150 30 314 2.3E-104 T 12-10-2018 VAPA_1c06930 5fd574b1237860b5b835c40f345da886 324 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 48 320 3.0E-77 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c06930 5fd574b1237860b5b835c40f345da886 324 PIRSF PIRSF017082 1 324 2.1E-71 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c15200 4f1215934dd349497d8d3166bd1e3da0 233 Pfam PF13534 4Fe-4S dicluster domain 143 216 1.2E-9 T 12-10-2018 VAPA_1c15200 4f1215934dd349497d8d3166bd1e3da0 233 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 144 155 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site VAPA_1c15200 4f1215934dd349497d8d3166bd1e3da0 233 Pfam PF13085 2Fe-2S iron-sulfur cluster binding domain 4 107 1.3E-32 T 12-10-2018 IPR025192 Succinate dehydogenase/fumarate reductase N-terminal GO:0009055|GO:0051536 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 VAPA_1c15200 4f1215934dd349497d8d3166bd1e3da0 233 SUPERFAMILY SSF46548 103 231 1.52E-38 T 12-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 VAPA_1c15200 4f1215934dd349497d8d3166bd1e3da0 233 SUPERFAMILY SSF54292 1 102 6.15E-29 T 12-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 VAPA_1c15200 4f1215934dd349497d8d3166bd1e3da0 233 Gene3D G3DSA:3.10.20.30 1 102 1.8E-36 T 12-10-2018 IPR012675 Beta-grasp domain superfamily VAPA_1c15200 4f1215934dd349497d8d3166bd1e3da0 233 Gene3D G3DSA:1.10.1060.10 103 233 3.8E-57 T 12-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 VAPA_1c15200 4f1215934dd349497d8d3166bd1e3da0 233 TIGRFAM TIGR00384 dhsB: succinate dehydrogenase and fumarate reductase iron-sulfur protein 7 225 3.3E-85 T 12-10-2018 IPR004489 Succinate dehydrogenase/fumarate reductase iron-sulphur protein GO:0006099|GO:0016491|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 VAPA_1c35730 c2aca6acd08385b6159ff5b16875af0a 405 Gene3D G3DSA:3.40.50.1820 3 232 1.2E-55 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c35730 c2aca6acd08385b6159ff5b16875af0a 405 Pfam PF01738 Dienelactone hydrolase family 17 231 1.7E-48 T 12-10-2018 IPR002925 Dienelactone hydrolase GO:0016787 VAPA_1c35730 c2aca6acd08385b6159ff5b16875af0a 405 SUPERFAMILY SSF53474 1 230 2.42E-45 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c35730 c2aca6acd08385b6159ff5b16875af0a 405 Gene3D G3DSA:3.10.450.50 245 377 1.6E-21 T 12-10-2018 VAPA_1c35730 c2aca6acd08385b6159ff5b16875af0a 405 SUPERFAMILY SSF54427 238 382 1.93E-23 T 12-10-2018 IPR032710 NTF2-like domain superfamily VAPA_1c08660 28bc6f73c458729005b1b26acfcd3966 471 Pfam PF00890 FAD binding domain 23 434 1.4E-47 T 12-10-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 VAPA_1c08660 28bc6f73c458729005b1b26acfcd3966 471 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 22 44 3.8E-5 T 12-10-2018 VAPA_1c08660 28bc6f73c458729005b1b26acfcd3966 471 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 450 465 3.8E-5 T 12-10-2018 VAPA_1c08660 28bc6f73c458729005b1b26acfcd3966 471 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 56 71 3.8E-5 T 12-10-2018 VAPA_1c08660 28bc6f73c458729005b1b26acfcd3966 471 SUPERFAMILY SSF56425 265 403 1.92E-19 T 12-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 VAPA_1c08660 28bc6f73c458729005b1b26acfcd3966 471 Gene3D G3DSA:3.50.50.60 23 460 1.7E-92 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c08660 28bc6f73c458729005b1b26acfcd3966 471 SUPERFAMILY SSF51905 16 462 9.18E-39 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c08660 28bc6f73c458729005b1b26acfcd3966 471 Gene3D G3DSA:3.90.700.10 258 399 1.7E-92 T 12-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 VAPA_2c01260 c2db289b8d2a5099923246b76ed3c776 213 Gene3D G3DSA:3.40.430.10 1 212 2.2E-48 T 12-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 VAPA_2c01260 c2db289b8d2a5099923246b76ed3c776 213 Pfam PF01872 RibD C-terminal domain 3 207 5.5E-23 T 12-10-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 VAPA_2c01260 c2db289b8d2a5099923246b76ed3c776 213 SUPERFAMILY SSF53597 3 207 5.24E-27 T 12-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 VAPA_2c09870 65636ab7a92a9ed56b9955615040128e 312 Gene3D G3DSA:3.90.180.10 14 307 1.8E-82 T 12-10-2018 VAPA_2c09870 65636ab7a92a9ed56b9955615040128e 312 Pfam PF13602 Zinc-binding dehydrogenase 190 307 2.4E-17 T 12-10-2018 VAPA_2c09870 65636ab7a92a9ed56b9955615040128e 312 SUPERFAMILY SSF50129 4 152 2.89E-34 T 12-10-2018 IPR011032 GroES-like superfamily VAPA_2c09870 65636ab7a92a9ed56b9955615040128e 312 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 148 169 - T 12-10-2018 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 VAPA_2c09870 65636ab7a92a9ed56b9955615040128e 312 Gene3D G3DSA:3.40.50.720 131 259 1.8E-82 T 12-10-2018 VAPA_2c09870 65636ab7a92a9ed56b9955615040128e 312 SMART SM00829 15 308 3.0E-29 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 VAPA_2c09870 65636ab7a92a9ed56b9955615040128e 312 SUPERFAMILY SSF51735 120 247 2.37E-32 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_2c09870 65636ab7a92a9ed56b9955615040128e 312 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 32 94 3.2E-11 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 VAPA_1c36510 0f9e771feb884cf6a445db75e03a64ee 70 TIGRFAM TIGR00030 S21p: ribosomal protein bS21 2 59 5.4E-24 T 12-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 VAPA_1c36510 0f9e771feb884cf6a445db75e03a64ee 70 PRINTS PR00976 Ribosomal protein S21 family signature 25 35 1.4E-14 T 12-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 VAPA_1c36510 0f9e771feb884cf6a445db75e03a64ee 70 PRINTS PR00976 Ribosomal protein S21 family signature 13 22 1.4E-14 T 12-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 VAPA_1c36510 0f9e771feb884cf6a445db75e03a64ee 70 PRINTS PR00976 Ribosomal protein S21 family signature 5 13 1.4E-14 T 12-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 VAPA_1c36510 0f9e771feb884cf6a445db75e03a64ee 70 PRINTS PR00976 Ribosomal protein S21 family signature 37 47 1.4E-14 T 12-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 VAPA_1c36510 0f9e771feb884cf6a445db75e03a64ee 70 Gene3D G3DSA:1.20.5.1150 16 54 7.1E-19 T 12-10-2018 IPR038380 Ribosomal protein S21 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 VAPA_1c36510 0f9e771feb884cf6a445db75e03a64ee 70 Pfam PF01165 Ribosomal protein S21 3 57 5.1E-20 T 12-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 VAPA_1c36510 0f9e771feb884cf6a445db75e03a64ee 70 ProDom PD005521 RIBOSOMAL S21 RIBONUCLEOPROTEIN 30S S21P A SSU SUBUNIT SEQUENCING DIRECT 16 42 3.0E-8 T 12-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 VAPA_1c36510 0f9e771feb884cf6a445db75e03a64ee 70 ProSitePatterns PS01181 Ribosomal protein S21 signature. 13 25 - T 12-10-2018 IPR018278 Ribosomal protein S21, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 VAPA_1c36510 0f9e771feb884cf6a445db75e03a64ee 70 Hamap MF_00358 30S ribosomal protein S21 [rpsU]. 1 57 20.093 T 12-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 VAPA_1c20440 cbaee8e27f6dade9f50cc8becc8c64c5 332 Gene3D G3DSA:3.40.190.150 35 322 1.4E-115 T 12-10-2018 VAPA_1c20440 cbaee8e27f6dade9f50cc8becc8c64c5 332 PIRSF PIRSF017082 1 332 6.2E-89 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c20440 cbaee8e27f6dade9f50cc8becc8c64c5 332 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 54 328 9.6E-91 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c20440 cbaee8e27f6dade9f50cc8becc8c64c5 332 Gene3D G3DSA:3.40.190.10 132 257 1.4E-115 T 12-10-2018 VAPA_1c20440 cbaee8e27f6dade9f50cc8becc8c64c5 332 SUPERFAMILY SSF53850 117 293 1.86E-17 T 12-10-2018 VAPA_1c03110 d71998689e48a3a3db977a11cf7978bd 316 Gene3D G3DSA:3.20.10.10 136 315 1.1E-51 T 12-10-2018 VAPA_1c03110 d71998689e48a3a3db977a11cf7978bd 316 TIGRFAM TIGR01122 ilvE_I: branched-chain amino acid aminotransferase 16 316 3.3E-134 T 12-10-2018 IPR005785 Branched-chain amino acid aminotransferase I GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|MetaCyc: PWY-7767 VAPA_1c03110 d71998689e48a3a3db977a11cf7978bd 316 Gene3D G3DSA:3.30.470.10 6 135 4.3E-42 T 12-10-2018 VAPA_1c03110 d71998689e48a3a3db977a11cf7978bd 316 Pfam PF01063 Amino-transferase class IV 41 272 6.1E-58 T 12-10-2018 IPR001544 Aminotransferase class IV GO:0003824 Reactome: R-HSA-70895 VAPA_1c03110 d71998689e48a3a3db977a11cf7978bd 316 SUPERFAMILY SSF56752 9 313 5.49E-103 T 12-10-2018 IPR036038 Aminotransferase-like, PLP-dependent enzymes GO:0003824 Reactome: R-HSA-70895 VAPA_1c03110 d71998689e48a3a3db977a11cf7978bd 316 ProSitePatterns PS00770 Aminotransferases class-IV signature. 199 228 - T 12-10-2018 IPR018300 Aminotransferase, class IV, conserved site GO:0003824 Reactome: R-HSA-70895 VAPA_1c40100 2e53cbc0b8b199c0fbea376be126cc2c 337 SMART SM00829 11 335 8.2E-27 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 VAPA_1c40100 2e53cbc0b8b199c0fbea376be126cc2c 337 SUPERFAMILY SSF50129 5 147 3.3E-33 T 12-10-2018 IPR011032 GroES-like superfamily VAPA_1c40100 2e53cbc0b8b199c0fbea376be126cc2c 337 Pfam PF13602 Zinc-binding dehydrogenase 190 335 6.4E-19 T 12-10-2018 VAPA_1c40100 2e53cbc0b8b199c0fbea376be126cc2c 337 Gene3D G3DSA:3.40.50.720 126 305 1.9E-85 T 12-10-2018 VAPA_1c40100 2e53cbc0b8b199c0fbea376be126cc2c 337 Gene3D G3DSA:3.90.180.10 9 333 1.9E-85 T 12-10-2018 VAPA_1c40100 2e53cbc0b8b199c0fbea376be126cc2c 337 SUPERFAMILY SSF51735 118 273 6.98E-40 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c40100 2e53cbc0b8b199c0fbea376be126cc2c 337 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 29 92 8.9E-8 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 VAPA_1c41680 4bab6d9914dc0015391b0d3c33f8eeac 285 Gene3D G3DSA:3.20.20.140 8 253 1.9E-80 T 12-10-2018 VAPA_1c41680 4bab6d9914dc0015391b0d3c33f8eeac 285 Gene3D G3DSA:1.10.150.650 100 172 1.9E-80 T 12-10-2018 VAPA_1c41680 4bab6d9914dc0015391b0d3c33f8eeac 285 SMART SM00481 7 72 1.6E-14 T 12-10-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal VAPA_1c41680 4bab6d9914dc0015391b0d3c33f8eeac 285 Pfam PF02811 PHP domain 8 123 2.2E-10 T 12-10-2018 IPR004013 PHP domain GO:0003824 VAPA_1c41680 4bab6d9914dc0015391b0d3c33f8eeac 285 SUPERFAMILY SSF89550 5 279 1.8E-46 T 12-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 VAPA_1c45970 f3cfe9705139ad87c18f704c1e1e2468 278 Gene3D G3DSA:3.40.50.1820 16 274 1.1E-47 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c45970 f3cfe9705139ad87c18f704c1e1e2468 278 SUPERFAMILY SSF53474 25 275 7.22E-47 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c45970 f3cfe9705139ad87c18f704c1e1e2468 278 Pfam PF12146 Serine aminopeptidase, S33 69 180 1.5E-13 T 12-10-2018 IPR022742 Serine aminopeptidase, S33 VAPA_1c49840 2873a4459162c86a2fc5d0b917818202 183 Gene3D G3DSA:3.40.50.10490 125 180 6.6E-7 T 12-10-2018 VAPA_1c49840 2873a4459162c86a2fc5d0b917818202 183 Gene3D G3DSA:3.40.50.10490 1 124 2.0E-31 T 12-10-2018 VAPA_1c49840 2873a4459162c86a2fc5d0b917818202 183 SUPERFAMILY SSF53697 2 174 1.03E-29 T 12-10-2018 VAPA_1c49840 2873a4459162c86a2fc5d0b917818202 183 Pfam PF13580 SIS domain 2 114 7.4E-26 T 12-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 VAPA_1c26530 1c908d5174f4637dfde7a6b04422f52a 304 Pfam PF03466 LysR substrate binding domain 90 284 6.3E-33 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_1c26530 1c908d5174f4637dfde7a6b04422f52a 304 Gene3D G3DSA:3.40.190.10 103 284 2.3E-42 T 12-10-2018 VAPA_1c26530 1c908d5174f4637dfde7a6b04422f52a 304 Gene3D G3DSA:1.10.10.10 7 90 5.7E-25 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c26530 1c908d5174f4637dfde7a6b04422f52a 304 SUPERFAMILY SSF46785 3 87 1.61E-22 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c26530 1c908d5174f4637dfde7a6b04422f52a 304 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 67 3.0E-21 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c26530 1c908d5174f4637dfde7a6b04422f52a 304 Gene3D G3DSA:3.40.190.10 164 263 2.3E-42 T 12-10-2018 VAPA_1c26530 1c908d5174f4637dfde7a6b04422f52a 304 SUPERFAMILY SSF53850 90 291 4.34E-32 T 12-10-2018 VAPA_1c26530 1c908d5174f4637dfde7a6b04422f52a 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 23 34 1.2E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c26530 1c908d5174f4637dfde7a6b04422f52a 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 44 55 1.2E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c26530 1c908d5174f4637dfde7a6b04422f52a 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 44 1.2E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c28150 670da8fe88744fab7ace5c8ac07d44e8 347 Gene3D G3DSA:1.10.3720.10 135 345 6.3E-20 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c28150 670da8fe88744fab7ace5c8ac07d44e8 347 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 163 344 2.0E-28 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 VAPA_1c28150 670da8fe88744fab7ace5c8ac07d44e8 347 SUPERFAMILY SSF161098 141 327 3.66E-22 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c28150 670da8fe88744fab7ace5c8ac07d44e8 347 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 10 50 1.4E-10 T 12-10-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain VAPA_1c49770 0eb56c8f28dd3cf64ab3524eed8ae805 990 Gene3D G3DSA:3.40.605.10 529 972 9.2E-140 T 12-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 VAPA_1c49770 0eb56c8f28dd3cf64ab3524eed8ae805 990 TIGRFAM TIGR01238 D1pyr5carbox3: delta-1-pyrroline-5-carboxylate dehydrogenase 524 968 1.5E-168 T 12-10-2018 IPR005933 Delta-1-pyrroline-5-carboxylate dehydrogenase 3 GO:0003842|GO:0006561|GO:0055114 KEGG: 00250+1.2.1.88|KEGG: 00330+1.5.5.2+1.2.1.88|MetaCyc: PWY-5737|MetaCyc: PWY-6853|MetaCyc: PWY-6922 VAPA_1c49770 0eb56c8f28dd3cf64ab3524eed8ae805 990 SUPERFAMILY SSF81935 6 155 1.01E-34 T 12-10-2018 IPR024089 Proline dehydrogenase PutA, domain I/II GO:0003842|GO:0055114 KEGG: 00250+1.2.1.88|KEGG: 00330+1.5.5.2+1.2.1.88|MetaCyc: PWY-5737|MetaCyc: PWY-6853|MetaCyc: PWY-6922 VAPA_1c49770 0eb56c8f28dd3cf64ab3524eed8ae805 990 Pfam PF14850 DNA-binding domain of Proline dehydrogenase 51 153 5.1E-25 T 12-10-2018 IPR024082 Proline dehydrogenase PutA, domain II GO:0003842|GO:0055114 KEGG: 00250+1.2.1.88|KEGG: 00330+1.5.5.2+1.2.1.88|MetaCyc: PWY-5737|MetaCyc: PWY-6853|MetaCyc: PWY-6922 VAPA_1c49770 0eb56c8f28dd3cf64ab3524eed8ae805 990 PIRSF PIRSF000197 523 988 1.1E-189 T 12-10-2018 IPR025703 Bifunctional protein PutA GO:0003700|GO:0003842|GO:0004657|GO:0006355|GO:0010133 KEGG: 00250+1.2.1.88|KEGG: 00330+1.5.5.2+1.2.1.88|MetaCyc: PWY-5737|MetaCyc: PWY-6853|MetaCyc: PWY-6922 VAPA_1c49770 0eb56c8f28dd3cf64ab3524eed8ae805 990 PIRSF PIRSF000197 6 530 3.3E-155 T 12-10-2018 IPR025703 Bifunctional protein PutA GO:0003700|GO:0003842|GO:0004657|GO:0006355|GO:0010133 KEGG: 00250+1.2.1.88|KEGG: 00330+1.5.5.2+1.2.1.88|MetaCyc: PWY-5737|MetaCyc: PWY-6853|MetaCyc: PWY-6922 VAPA_1c49770 0eb56c8f28dd3cf64ab3524eed8ae805 990 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 771 782 - T 12-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 VAPA_1c49770 0eb56c8f28dd3cf64ab3524eed8ae805 990 SUPERFAMILY SSF51730 156 495 1.84E-101 T 12-10-2018 IPR029041 FAD-linked oxidoreductase-like VAPA_1c49770 0eb56c8f28dd3cf64ab3524eed8ae805 990 Pfam PF00171 Aldehyde dehydrogenase family 528 972 9.5E-110 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 VAPA_1c49770 0eb56c8f28dd3cf64ab3524eed8ae805 990 SUPERFAMILY SSF53720 529 975 3.8E-121 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 VAPA_1c49770 0eb56c8f28dd3cf64ab3524eed8ae805 990 Pfam PF01619 Proline dehydrogenase 170 461 8.1E-92 T 12-10-2018 IPR002872 Proline dehydrogenase domain KEGG: 00330+1.5.5.2|MetaCyc: PWY-5737|MetaCyc: PWY-6922|Reactome: R-HSA-70688 VAPA_1c49770 0eb56c8f28dd3cf64ab3524eed8ae805 990 Gene3D G3DSA:3.40.309.10 746 939 9.2E-140 T 12-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 VAPA_1c49770 0eb56c8f28dd3cf64ab3524eed8ae805 990 Gene3D G3DSA:3.20.20.220 98 491 6.6E-131 T 12-10-2018 VAPA_2c09400 e7a295b119936d7971a3789cdd9f6595 1035 SUPERFAMILY SSF82693 42 132 1.02E-24 T 12-10-2018 VAPA_2c09400 e7a295b119936d7971a3789cdd9f6595 1035 Gene3D G3DSA:3.30.70.1320 135 335 6.8E-238 T 12-10-2018 VAPA_2c09400 e7a295b119936d7971a3789cdd9f6595 1035 Gene3D G3DSA:1.20.1640.10 10 522 6.8E-238 T 12-10-2018 VAPA_2c09400 e7a295b119936d7971a3789cdd9f6595 1035 SUPERFAMILY SSF82693 680 830 4.66E-12 T 12-10-2018 VAPA_2c09400 e7a295b119936d7971a3789cdd9f6595 1035 Gene3D G3DSA:1.20.1640.10 523 576 6.8E-238 T 12-10-2018 VAPA_2c09400 e7a295b119936d7971a3789cdd9f6595 1035 SUPERFAMILY SSF82714 730 816 1.57E-21 T 12-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains VAPA_2c09400 e7a295b119936d7971a3789cdd9f6595 1035 SUPERFAMILY SSF82693 575 679 4.87E-20 T 12-10-2018 VAPA_2c09400 e7a295b119936d7971a3789cdd9f6595 1035 Gene3D G3DSA:3.30.2090.10 729 817 6.8E-238 T 12-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains VAPA_2c09400 e7a295b119936d7971a3789cdd9f6595 1035 Gene3D G3DSA:3.30.2090.10 181 278 6.8E-238 T 12-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains VAPA_2c09400 e7a295b119936d7971a3789cdd9f6595 1035 SUPERFAMILY SSF82693 141 333 9.94E-21 T 12-10-2018 VAPA_2c09400 e7a295b119936d7971a3789cdd9f6595 1035 SUPERFAMILY SSF82714 185 275 2.88E-21 T 12-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains VAPA_2c09400 e7a295b119936d7971a3789cdd9f6595 1035 Gene3D G3DSA:3.30.70.1440 677 829 6.8E-238 T 12-10-2018 VAPA_2c09400 e7a295b119936d7971a3789cdd9f6595 1035 Gene3D G3DSA:3.30.70.1430 40 825 6.8E-238 T 12-10-2018 VAPA_2c09400 e7a295b119936d7971a3789cdd9f6595 1035 Gene3D G3DSA:3.30.70.1430 577 676 6.8E-238 T 12-10-2018 VAPA_2c09400 e7a295b119936d7971a3789cdd9f6595 1035 PRINTS PR00702 Acriflavin resistance protein family signature 394 418 5.4E-88 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 VAPA_2c09400 e7a295b119936d7971a3789cdd9f6595 1035 PRINTS PR00702 Acriflavin resistance protein family signature 10 34 5.4E-88 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 VAPA_2c09400 e7a295b119936d7971a3789cdd9f6595 1035 PRINTS PR00702 Acriflavin resistance protein family signature 631 645 5.4E-88 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 VAPA_2c09400 e7a295b119936d7971a3789cdd9f6595 1035 PRINTS PR00702 Acriflavin resistance protein family signature 447 470 5.4E-88 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 VAPA_2c09400 e7a295b119936d7971a3789cdd9f6595 1035 PRINTS PR00702 Acriflavin resistance protein family signature 562 579 5.4E-88 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 VAPA_2c09400 e7a295b119936d7971a3789cdd9f6595 1035 PRINTS PR00702 Acriflavin resistance protein family signature 366 387 5.4E-88 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 VAPA_2c09400 e7a295b119936d7971a3789cdd9f6595 1035 PRINTS PR00702 Acriflavin resistance protein family signature 339 362 5.4E-88 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 VAPA_2c09400 e7a295b119936d7971a3789cdd9f6595 1035 PRINTS PR00702 Acriflavin resistance protein family signature 472 495 5.4E-88 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 VAPA_2c09400 e7a295b119936d7971a3789cdd9f6595 1035 PRINTS PR00702 Acriflavin resistance protein family signature 38 56 5.4E-88 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 VAPA_2c09400 e7a295b119936d7971a3789cdd9f6595 1035 Pfam PF00873 AcrB/AcrD/AcrF family 3 829 5.3E-259 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 VAPA_2c09400 e7a295b119936d7971a3789cdd9f6595 1035 SUPERFAMILY SSF82866 299 499 3.66E-51 T 12-10-2018 VAPA_1c14050 bb74f3223cbd10d136ba09ce81b95f67 446 SUPERFAMILY SSF103473 28 438 2.09E-67 T 12-10-2018 IPR036259 MFS transporter superfamily VAPA_1c14050 bb74f3223cbd10d136ba09ce81b95f67 446 TIGRFAM TIGR00883 2A0106: MFS transporter, metabolite:H+ symporter (MHS) family protein 41 429 6.5E-140 T 12-10-2018 IPR004736 MFS transporter, metabolite:H symporter GO:0016021|GO:0022857|GO:0055085 VAPA_1c14050 bb74f3223cbd10d136ba09ce81b95f67 446 Pfam PF07690 Major Facilitator Superfamily 269 433 6.8E-11 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 VAPA_1c14050 bb74f3223cbd10d136ba09ce81b95f67 446 ProSitePatterns PS00217 Sugar transport proteins signature 2. 144 169 - T 12-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 VAPA_1c14050 bb74f3223cbd10d136ba09ce81b95f67 446 Gene3D G3DSA:1.20.1250.20 32 441 5.3E-65 T 12-10-2018 VAPA_1c14050 bb74f3223cbd10d136ba09ce81b95f67 446 Pfam PF00083 Sugar (and other) transporter 35 232 6.2E-24 T 12-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 VAPA_2c04240 839c598080189eec171948c4fca755f7 216 Pfam PF00881 Nitroreductase family 45 210 4.2E-24 T 12-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 VAPA_2c04240 839c598080189eec171948c4fca755f7 216 SUPERFAMILY SSF55469 43 211 4.14E-25 T 12-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 VAPA_2c04240 839c598080189eec171948c4fca755f7 216 Gene3D G3DSA:3.40.109.10 18 213 1.5E-52 T 12-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 VAPA_1c40010 5fee47e1b4c817350bf58fc02a63b742 293 SUPERFAMILY SSF53850 90 293 9.41E-44 T 12-10-2018 VAPA_1c40010 5fee47e1b4c817350bf58fc02a63b742 293 Gene3D G3DSA:1.10.10.10 2 91 8.1E-24 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c40010 5fee47e1b4c817350bf58fc02a63b742 293 Gene3D G3DSA:3.40.190.10 163 263 4.9E-63 T 12-10-2018 VAPA_1c40010 5fee47e1b4c817350bf58fc02a63b742 293 Gene3D G3DSA:3.40.190.10 92 290 4.9E-63 T 12-10-2018 VAPA_1c40010 5fee47e1b4c817350bf58fc02a63b742 293 Pfam PF03466 LysR substrate binding domain 90 292 8.6E-43 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_1c40010 5fee47e1b4c817350bf58fc02a63b742 293 SUPERFAMILY SSF46785 4 84 1.03E-18 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c40010 5fee47e1b4c817350bf58fc02a63b742 293 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 2.5E-16 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c09520 86a4890a492ebdc76045db2afd382ee6 294 Pfam PF01678 Diaminopimelate epimerase 5 127 9.1E-32 T 12-10-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 VAPA_1c09520 86a4890a492ebdc76045db2afd382ee6 294 Pfam PF01678 Diaminopimelate epimerase 169 282 1.4E-30 T 12-10-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 VAPA_1c09520 86a4890a492ebdc76045db2afd382ee6 294 SUPERFAMILY SSF54506 159 289 8.97E-50 T 12-10-2018 VAPA_1c09520 86a4890a492ebdc76045db2afd382ee6 294 Gene3D G3DSA:3.10.310.10 124 283 3.8E-97 T 12-10-2018 VAPA_1c09520 86a4890a492ebdc76045db2afd382ee6 294 ProSitePatterns PS01326 Diaminopimelate epimerase signature. 69 83 - T 12-10-2018 IPR018510 Diaminopimelate epimerase, active site GO:0005737|GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 VAPA_1c09520 86a4890a492ebdc76045db2afd382ee6 294 Hamap MF_00197 Diaminopimelate epimerase [dapF]. 3 290 37.832 T 12-10-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 VAPA_1c09520 86a4890a492ebdc76045db2afd382ee6 294 SUPERFAMILY SSF54506 3 135 6.11E-44 T 12-10-2018 VAPA_1c09520 86a4890a492ebdc76045db2afd382ee6 294 Gene3D G3DSA:3.10.310.10 5 286 3.8E-97 T 12-10-2018 VAPA_1c09520 86a4890a492ebdc76045db2afd382ee6 294 TIGRFAM TIGR00652 DapF: diaminopimelate epimerase 3 288 4.7E-86 T 12-10-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 VAPA_1c03120 569fd767c3778deb0b0e2d9fc8e21d2f 69 Gene3D G3DSA:2.60.260.40 13 60 5.9E-10 T 12-10-2018 VAPA_1c03120 569fd767c3778deb0b0e2d9fc8e21d2f 69 Pfam PF10276 Zinc-finger domain 34 57 1.7E-8 T 12-10-2018 IPR019401 Zinc finger, CHCC-type Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VAPA_1c31880 459ce8d3bac099476aadedf24f88ab00 234 Pfam PF00072 Response regulator receiver domain 3 112 1.5E-24 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_1c31880 459ce8d3bac099476aadedf24f88ab00 234 Pfam PF00486 Transcriptional regulatory protein, C terminal 148 218 7.7E-15 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 VAPA_1c31880 459ce8d3bac099476aadedf24f88ab00 234 Gene3D G3DSA:3.40.50.2300 1 118 2.5E-34 T 12-10-2018 VAPA_1c31880 459ce8d3bac099476aadedf24f88ab00 234 Gene3D G3DSA:1.10.10.10 119 223 6.4E-21 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c31880 459ce8d3bac099476aadedf24f88ab00 234 SUPERFAMILY SSF52172 1 175 5.12E-36 T 12-10-2018 IPR011006 CheY-like superfamily VAPA_1c31880 459ce8d3bac099476aadedf24f88ab00 234 SMART SM00862 145 218 2.1E-14 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 VAPA_1c31880 459ce8d3bac099476aadedf24f88ab00 234 SMART SM00448 1 112 4.0E-34 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_2c06310 72ad5762333dbd04c3ba52b4ea46b582 212 Pfam PF02108 Flagellar assembly protein FliH 94 193 4.0E-8 T 12-10-2018 IPR018035 Flagellar assembly protein FliH/Type III secretion system HrpE VAPA_2c06310 72ad5762333dbd04c3ba52b4ea46b582 212 TIGRFAM TIGR02499 HrpE_YscL_not: type III secretion apparatus protein, HrpE/YscL family 19 186 3.1E-31 T 12-10-2018 IPR012842 Type III secretion system HrpE/YscL VAPA_1c37160 e96027371da57a772fc3555afb8de807 543 SUPERFAMILY SSF53850 44 538 9.05E-105 T 12-10-2018 VAPA_1c37160 e96027371da57a772fc3555afb8de807 543 Gene3D G3DSA:3.90.76.10 55 204 3.1E-95 T 12-10-2018 VAPA_1c37160 e96027371da57a772fc3555afb8de807 543 Gene3D G3DSA:3.10.105.10 292 519 3.1E-95 T 12-10-2018 VAPA_1c37160 e96027371da57a772fc3555afb8de807 543 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 89 467 5.2E-79 T 12-10-2018 IPR000914 Solute-binding protein family 5 domain VAPA_1c37160 e96027371da57a772fc3555afb8de807 543 Gene3D G3DSA:3.40.190.10 205 528 3.1E-95 T 12-10-2018 VAPA_1c37160 e96027371da57a772fc3555afb8de807 543 PIRSF PIRSF002741 16 543 3.8E-67 T 12-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 VAPA_1c13480 bab8d5bbf1798d5abc519c9bc6e0497b 57 ProSitePatterns PS00582 Ribosomal protein L33 signature. 23 42 - T 12-10-2018 IPR018264 Ribosomal protein L33, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 VAPA_1c13480 bab8d5bbf1798d5abc519c9bc6e0497b 57 Pfam PF00471 Ribosomal protein L33 9 55 9.3E-17 T 12-10-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 VAPA_1c13480 bab8d5bbf1798d5abc519c9bc6e0497b 57 SUPERFAMILY SSF57829 4 55 5.68E-18 T 12-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 VAPA_1c13480 bab8d5bbf1798d5abc519c9bc6e0497b 57 Gene3D G3DSA:2.20.28.120 3 57 2.7E-26 T 12-10-2018 IPR038584 Ribosomal protein L33 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 VAPA_1c13480 bab8d5bbf1798d5abc519c9bc6e0497b 57 Hamap MF_00294 50S ribosomal protein L33 [rpmG]. 7 55 13.906 T 12-10-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 VAPA_1c13480 bab8d5bbf1798d5abc519c9bc6e0497b 57 TIGRFAM TIGR01023 rpmG_bact: ribosomal protein bL33 4 57 1.2E-23 T 12-10-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 VAPA_1c35810 cc610f41384507defc00e798d2bd0dfd 453 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 23 148 8.8E-8 T 12-10-2018 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 VAPA_1c35810 cc610f41384507defc00e798d2bd0dfd 453 SUPERFAMILY SSF51735 14 150 3.33E-23 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c35810 cc610f41384507defc00e798d2bd0dfd 453 SMART SM00858 361 426 9.2E-6 T 12-10-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 VAPA_1c35810 cc610f41384507defc00e798d2bd0dfd 453 Gene3D G3DSA:3.40.50.720 10 174 3.2E-22 T 12-10-2018 VAPA_1c39100 49c77a8ecb28556c0b70ae4d6c5a2f90 290 SUPERFAMILY SSF52540 16 242 5.07E-76 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c39100 49c77a8ecb28556c0b70ae4d6c5a2f90 290 SMART SM00382 46 235 5.8E-15 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c39100 49c77a8ecb28556c0b70ae4d6c5a2f90 290 ProSitePatterns PS00211 ABC transporters family signature. 158 172 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_1c39100 49c77a8ecb28556c0b70ae4d6c5a2f90 290 Pfam PF00005 ABC transporter 38 186 1.3E-35 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c39100 49c77a8ecb28556c0b70ae4d6c5a2f90 290 Gene3D G3DSA:3.40.50.300 14 290 3.3E-79 T 12-10-2018 VAPA_2c12020 c93d3c5ce42ea6d2130ce044f5338cac 487 Pfam PF00884 Sulfatase 8 347 6.7E-49 T 12-10-2018 IPR000917 Sulfatase, N-terminal GO:0008484 VAPA_2c12020 c93d3c5ce42ea6d2130ce044f5338cac 487 SUPERFAMILY SSF53649 7 442 7.85E-104 T 12-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 VAPA_2c12020 c93d3c5ce42ea6d2130ce044f5338cac 487 Gene3D G3DSA:3.40.720.10 7 462 3.5E-108 T 12-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 VAPA_1c41410 fcb06ea33a5d7b17c559a77cb4000dde 87 Pfam PF06904 Extensin-like protein C-terminus 1 83 4.5E-25 T 12-10-2018 IPR009683 Extensin-like, C-terminal VAPA_1c47130 16fd1d0743c27606a23be58bcbda2f0f 237 Pfam PF00072 Response regulator receiver domain 12 121 1.2E-15 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_1c47130 16fd1d0743c27606a23be58bcbda2f0f 237 Gene3D G3DSA:3.40.50.2300 8 136 6.5E-22 T 12-10-2018 VAPA_1c47130 16fd1d0743c27606a23be58bcbda2f0f 237 SUPERFAMILY SSF52172 5 131 2.85E-26 T 12-10-2018 IPR011006 CheY-like superfamily VAPA_1c47130 16fd1d0743c27606a23be58bcbda2f0f 237 SUPERFAMILY SSF46894 159 236 2.52E-12 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 VAPA_1c47130 16fd1d0743c27606a23be58bcbda2f0f 237 Gene3D G3DSA:1.10.10.10 153 237 3.3E-14 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c47130 16fd1d0743c27606a23be58bcbda2f0f 237 SMART SM00448 10 121 2.8E-22 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_1c47130 16fd1d0743c27606a23be58bcbda2f0f 237 Pfam PF00486 Transcriptional regulatory protein, C terminal 160 235 3.9E-10 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 VAPA_1c47130 16fd1d0743c27606a23be58bcbda2f0f 237 SMART SM00862 160 235 9.4E-9 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 VAPA_1c11010 39f6c37450fffcc655b49f3794188a70 506 Gene3D G3DSA:3.40.50.300 1 245 1.6E-57 T 12-10-2018 VAPA_1c11010 39f6c37450fffcc655b49f3794188a70 506 Pfam PF00005 ABC transporter 25 178 2.7E-29 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c11010 39f6c37450fffcc655b49f3794188a70 506 SUPERFAMILY SSF52540 8 235 3.94E-59 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c11010 39f6c37450fffcc655b49f3794188a70 506 Gene3D G3DSA:3.40.50.300 277 502 2.6E-48 T 12-10-2018 VAPA_1c11010 39f6c37450fffcc655b49f3794188a70 506 SUPERFAMILY SSF52540 282 488 3.77E-48 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c11010 39f6c37450fffcc655b49f3794188a70 506 SMART SM00382 34 226 7.8E-9 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c11010 39f6c37450fffcc655b49f3794188a70 506 SMART SM00382 291 484 5.8E-7 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c11010 39f6c37450fffcc655b49f3794188a70 506 Pfam PF00005 ABC transporter 283 436 1.5E-21 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c11010 39f6c37450fffcc655b49f3794188a70 506 ProSitePatterns PS00211 ABC transporters family signature. 409 423 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_2c10500 d9279cf5a387e338ba4a2fe1894b71b5 316 Gene3D G3DSA:1.10.10.10 3 90 1.3E-23 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_2c10500 d9279cf5a387e338ba4a2fe1894b71b5 316 Gene3D G3DSA:3.40.190.290 91 292 4.0E-50 T 12-10-2018 VAPA_2c10500 d9279cf5a387e338ba4a2fe1894b71b5 316 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 2.3E-5 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_2c10500 d9279cf5a387e338ba4a2fe1894b71b5 316 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 2.3E-5 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_2c10500 d9279cf5a387e338ba4a2fe1894b71b5 316 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 2.3E-5 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_2c10500 d9279cf5a387e338ba4a2fe1894b71b5 316 SUPERFAMILY SSF46785 4 111 1.02E-19 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_2c10500 d9279cf5a387e338ba4a2fe1894b71b5 316 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 63 6.3E-18 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_2c10500 d9279cf5a387e338ba4a2fe1894b71b5 316 Pfam PF03466 LysR substrate binding domain 88 292 6.0E-38 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_2c10500 d9279cf5a387e338ba4a2fe1894b71b5 316 SUPERFAMILY SSF53850 88 296 1.32E-39 T 12-10-2018 VAPA_2c02890 3aeacba8723e1d929d619aa2513f00c5 270 SMART SM00062 43 263 2.3E-45 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF VAPA_2c02890 3aeacba8723e1d929d619aa2513f00c5 270 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 44 261 4.1E-53 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF VAPA_2c02890 3aeacba8723e1d929d619aa2513f00c5 270 Gene3D G3DSA:3.40.190.10 38 256 9.7E-57 T 12-10-2018 VAPA_2c02890 3aeacba8723e1d929d619aa2513f00c5 270 SUPERFAMILY SSF53850 17 262 2.12E-57 T 12-10-2018 VAPA_2c02890 3aeacba8723e1d929d619aa2513f00c5 270 Gene3D G3DSA:3.40.190.10 130 221 9.7E-57 T 12-10-2018 VAPA_2c00220 b9bc7ad9ec2d0b29bcbb943be6409ab6 317 SUPERFAMILY SSF52317 1 193 2.03E-48 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like VAPA_2c00220 b9bc7ad9ec2d0b29bcbb943be6409ab6 317 Pfam PF01965 DJ-1/PfpI family 1 174 1.2E-24 T 12-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 VAPA_2c00220 b9bc7ad9ec2d0b29bcbb943be6409ab6 317 SUPERFAMILY SSF46689 215 262 1.73E-10 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 VAPA_2c00220 b9bc7ad9ec2d0b29bcbb943be6409ab6 317 SMART SM00342 229 312 4.2E-22 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 VAPA_2c00220 b9bc7ad9ec2d0b29bcbb943be6409ab6 317 SUPERFAMILY SSF46689 266 315 8.61E-7 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 VAPA_2c00220 b9bc7ad9ec2d0b29bcbb943be6409ab6 317 Pfam PF12833 Helix-turn-helix domain 235 314 5.2E-21 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 VAPA_2c00220 b9bc7ad9ec2d0b29bcbb943be6409ab6 317 Gene3D G3DSA:1.10.10.60 214 317 5.2E-25 T 12-10-2018 VAPA_2c00220 b9bc7ad9ec2d0b29bcbb943be6409ab6 317 Gene3D G3DSA:3.40.50.880 1 213 2.5E-61 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like VAPA_1c23960 b0feea156dea6fd10da2474cfb057d0f 183 Gene3D G3DSA:1.20.58.320 5 83 2.0E-31 T 12-10-2018 VAPA_1c23960 b0feea156dea6fd10da2474cfb057d0f 183 Pfam PF06041 Bacterial protein of unknown function (DUF924) 12 180 1.1E-57 T 12-10-2018 IPR010323 Protein of unknown function DUF924 VAPA_1c23960 b0feea156dea6fd10da2474cfb057d0f 183 SUPERFAMILY SSF48452 6 179 2.31E-67 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 VAPA_1c23960 b0feea156dea6fd10da2474cfb057d0f 183 Gene3D G3DSA:1.25.40.10 84 183 1.4E-35 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 VAPA_1c48060 8c3e85f5d086194b4032850e6bd1be0d 222 Pfam PF01553 Acyltransferase 32 157 1.2E-18 T 12-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 VAPA_1c48060 8c3e85f5d086194b4032850e6bd1be0d 222 SUPERFAMILY SSF69593 20 211 4.32E-32 T 12-10-2018 VAPA_1c48060 8c3e85f5d086194b4032850e6bd1be0d 222 SMART SM00563 38 160 1.1E-14 T 12-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 VAPA_1c26320 d314aa6abcc2363f5f5eaa3e4292bab3 635 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 35 144 4.2E-5 T 12-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 VAPA_1c26320 d314aa6abcc2363f5f5eaa3e4292bab3 635 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 372 493 1.4E-16 T 12-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 VAPA_1c26320 d314aa6abcc2363f5f5eaa3e4292bab3 635 Pfam PF12806 Acetyl-CoA dehydrogenase C-terminal like 512 631 4.7E-27 T 12-10-2018 IPR025878 Acetyl-CoA dehydrogenase-like C-terminal domain VAPA_1c26320 d314aa6abcc2363f5f5eaa3e4292bab3 635 Gene3D G3DSA:1.20.140.10 323 501 1.3E-41 T 12-10-2018 VAPA_1c26320 d314aa6abcc2363f5f5eaa3e4292bab3 635 SUPERFAMILY SSF47203 322 501 9.18E-38 T 12-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 VAPA_1c26320 d314aa6abcc2363f5f5eaa3e4292bab3 635 Gene3D G3DSA:2.40.110.10 155 322 8.4E-24 T 12-10-2018 VAPA_1c26320 d314aa6abcc2363f5f5eaa3e4292bab3 635 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 157 241 1.7E-10 T 12-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 VAPA_1c26320 d314aa6abcc2363f5f5eaa3e4292bab3 635 Gene3D G3DSA:1.10.540.10 7 153 2.5E-8 T 12-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 VAPA_1c26320 d314aa6abcc2363f5f5eaa3e4292bab3 635 Pfam PF12418 Acyl-CoA dehydrogenase N terminal 7 30 2.7E-6 T 12-10-2018 IPR020953 Acyl-CoA dehydrogenase, N-terminal, bacteria VAPA_1c26320 d314aa6abcc2363f5f5eaa3e4292bab3 635 SUPERFAMILY SSF56645 32 295 5.24E-39 T 12-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 VAPA_1c00800 5493be467145e38d82d35a07ead8d9ce 330 Gene3D G3DSA:3.40.190.150 32 319 5.2E-83 T 12-10-2018 VAPA_1c00800 5493be467145e38d82d35a07ead8d9ce 330 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 64 325 2.7E-60 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c00800 5493be467145e38d82d35a07ead8d9ce 330 SUPERFAMILY SSF53850 122 284 3.37E-5 T 12-10-2018 VAPA_1c00800 5493be467145e38d82d35a07ead8d9ce 330 PIRSF PIRSF017082 1 329 1.8E-53 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c00800 5493be467145e38d82d35a07ead8d9ce 330 Gene3D G3DSA:3.40.190.10 129 254 5.2E-83 T 12-10-2018 VAPA_1c11550 c89831a8ab340d10becf553f8cb512f0 350 Pfam PF00005 ABC transporter 25 166 1.4E-32 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c11550 c89831a8ab340d10becf553f8cb512f0 350 SMART SM00382 33 216 6.4E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c11550 c89831a8ab340d10becf553f8cb512f0 350 SUPERFAMILY SSF50331 250 344 1.64E-7 T 12-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal VAPA_1c11550 c89831a8ab340d10becf553f8cb512f0 350 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_1c11550 c89831a8ab340d10becf553f8cb512f0 350 Pfam PF08402 TOBE domain 275 344 3.3E-9 T 12-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 VAPA_1c11550 c89831a8ab340d10becf553f8cb512f0 350 SUPERFAMILY SSF52540 5 242 6.34E-84 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c11550 c89831a8ab340d10becf553f8cb512f0 350 Gene3D G3DSA:3.40.50.300 3 260 5.6E-77 T 12-10-2018 VAPA_1c18370 c1bfe76d9152f87a129e03ec2345fab9 254 Pfam PF00005 ABC transporter 23 178 3.4E-28 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c18370 c1bfe76d9152f87a129e03ec2345fab9 254 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 226 247 9.0E-7 T 12-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal VAPA_1c18370 c1bfe76d9152f87a129e03ec2345fab9 254 Gene3D G3DSA:3.40.50.300 5 252 4.7E-53 T 12-10-2018 VAPA_1c18370 c1bfe76d9152f87a129e03ec2345fab9 254 SUPERFAMILY SSF52540 5 247 1.46E-54 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c18370 c1bfe76d9152f87a129e03ec2345fab9 254 SMART SM00382 31 225 1.7E-7 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c43800 f999a4ff5930730c292d6ac0f8e7a861 321 Pfam PF01478 Type IV leader peptidase family 161 270 8.5E-22 T 12-10-2018 IPR000045 Prepilin type IV endopeptidase, peptidase domain GO:0004190|GO:0016020 VAPA_1c43800 f999a4ff5930730c292d6ac0f8e7a861 321 Pfam PF06750 Bacterial Peptidase A24 N-terminal domain 14 150 5.1E-34 T 12-10-2018 IPR010627 Peptidase A24A, N-terminal VAPA_1c43800 f999a4ff5930730c292d6ac0f8e7a861 321 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 250 265 1.1E-20 T 12-10-2018 IPR014032 Peptidase A24A, prepilin type IV, bacterial VAPA_1c43800 f999a4ff5930730c292d6ac0f8e7a861 321 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 227 237 1.1E-20 T 12-10-2018 IPR014032 Peptidase A24A, prepilin type IV, bacterial VAPA_1c43800 f999a4ff5930730c292d6ac0f8e7a861 321 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 238 249 1.1E-20 T 12-10-2018 IPR014032 Peptidase A24A, prepilin type IV, bacterial VAPA_1c43800 f999a4ff5930730c292d6ac0f8e7a861 321 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 169 186 1.1E-20 T 12-10-2018 IPR014032 Peptidase A24A, prepilin type IV, bacterial VAPA_1c19970 848c4208792bce3bacbe71b162b4b5ba 352 Gene3D G3DSA:1.10.287.130 81 189 1.5E-19 T 12-10-2018 VAPA_1c19970 848c4208792bce3bacbe71b162b4b5ba 352 Pfam PF00672 HAMP domain 83 132 1.1E-9 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 VAPA_1c19970 848c4208792bce3bacbe71b162b4b5ba 352 SMART SM00304 83 135 1.6E-7 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 VAPA_1c19970 848c4208792bce3bacbe71b162b4b5ba 352 SUPERFAMILY SSF55874 198 346 3.8E-30 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_1c19970 848c4208792bce3bacbe71b162b4b5ba 352 SMART SM00388 136 201 5.7E-6 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 VAPA_1c19970 848c4208792bce3bacbe71b162b4b5ba 352 Gene3D G3DSA:3.30.565.10 197 351 1.1E-27 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_1c19970 848c4208792bce3bacbe71b162b4b5ba 352 PRINTS PR00344 Bacterial sensor protein C-terminal signature 308 326 2.3E-13 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c19970 848c4208792bce3bacbe71b162b4b5ba 352 PRINTS PR00344 Bacterial sensor protein C-terminal signature 273 287 2.3E-13 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c19970 848c4208792bce3bacbe71b162b4b5ba 352 PRINTS PR00344 Bacterial sensor protein C-terminal signature 291 301 2.3E-13 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c19970 848c4208792bce3bacbe71b162b4b5ba 352 PRINTS PR00344 Bacterial sensor protein C-terminal signature 332 345 2.3E-13 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c19970 848c4208792bce3bacbe71b162b4b5ba 352 SUPERFAMILY SSF47384 120 188 5.3E-12 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 VAPA_1c19970 848c4208792bce3bacbe71b162b4b5ba 352 SMART SM00387 239 348 5.9E-24 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase VAPA_1c19970 848c4208792bce3bacbe71b162b4b5ba 352 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 243 346 1.9E-18 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase VAPA_1c19970 848c4208792bce3bacbe71b162b4b5ba 352 Pfam PF00512 His Kinase A (phospho-acceptor) domain 137 183 2.7E-7 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 VAPA_1c24200 9ecdd348f9b866972b1a2024b4a283af 252 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 72 243 2.0E-21 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 VAPA_1c24200 9ecdd348f9b866972b1a2024b4a283af 252 Gene3D G3DSA:1.10.3720.10 47 247 5.8E-20 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c24200 9ecdd348f9b866972b1a2024b4a283af 252 SUPERFAMILY SSF161098 51 233 6.54E-25 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c18860 9a747493c1834c70d885475e361f443a 297 Pfam PF01476 LysM domain 73 115 6.6E-10 T 12-10-2018 IPR018392 LysM domain VAPA_1c18860 9a747493c1834c70d885475e361f443a 297 SUPERFAMILY SSF51261 72 294 1.57E-46 T 12-10-2018 IPR011055 Duplicated hybrid motif VAPA_1c18860 9a747493c1834c70d885475e361f443a 297 Gene3D G3DSA:3.10.350.10 64 130 3.5E-13 T 12-10-2018 IPR036779 LysM domain superfamily VAPA_1c18860 9a747493c1834c70d885475e361f443a 297 SMART SM00257 72 116 3.7E-6 T 12-10-2018 IPR018392 LysM domain VAPA_1c18860 9a747493c1834c70d885475e361f443a 297 Gene3D G3DSA:2.70.70.10 167 295 4.8E-34 T 12-10-2018 IPR011055 Duplicated hybrid motif VAPA_1c18860 9a747493c1834c70d885475e361f443a 297 Pfam PF01551 Peptidase family M23 196 290 2.0E-29 T 12-10-2018 IPR016047 Peptidase M23 VAPA_2c05000 8efc9ef61e4e9f4c1b87a89667ff6741 144 Pfam PF01022 Bacterial regulatory protein, arsR family 34 78 4.6E-13 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 VAPA_2c05000 8efc9ef61e4e9f4c1b87a89667ff6741 144 SMART SM00418 26 107 2.6E-21 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 VAPA_2c05000 8efc9ef61e4e9f4c1b87a89667ff6741 144 Gene3D G3DSA:1.10.10.10 6 119 7.1E-27 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_2c05000 8efc9ef61e4e9f4c1b87a89667ff6741 144 SUPERFAMILY SSF46785 18 102 1.15E-24 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_2c05000 8efc9ef61e4e9f4c1b87a89667ff6741 144 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 60 75 4.1E-12 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 VAPA_2c05000 8efc9ef61e4e9f4c1b87a89667ff6741 144 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 75 90 4.1E-12 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 VAPA_2c05000 8efc9ef61e4e9f4c1b87a89667ff6741 144 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 28 43 4.1E-12 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 VAPA_1c33980 87c12739f66579f6b7a0f5b71e83d3a4 567 Gene3D G3DSA:3.30.70.20 466 562 1.1E-40 T 12-10-2018 VAPA_1c33980 87c12739f66579f6b7a0f5b71e83d3a4 567 Pfam PF05187 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S 461 564 1.8E-50 T 12-10-2018 VAPA_1c33980 87c12739f66579f6b7a0f5b71e83d3a4 567 SUPERFAMILY SSF54862 465 566 1.24E-28 T 12-10-2018 VAPA_1c33980 87c12739f66579f6b7a0f5b71e83d3a4 567 Gene3D G3DSA:3.50.50.60 17 402 3.3E-196 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c33980 87c12739f66579f6b7a0f5b71e83d3a4 567 SUPERFAMILY SSF54373 220 323 1.53E-33 T 12-10-2018 VAPA_1c33980 87c12739f66579f6b7a0f5b71e83d3a4 567 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 296 311 1.6E-5 T 12-10-2018 VAPA_1c33980 87c12739f66579f6b7a0f5b71e83d3a4 567 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 19 41 1.6E-5 T 12-10-2018 VAPA_1c33980 87c12739f66579f6b7a0f5b71e83d3a4 567 Gene3D G3DSA:3.30.9.90 89 465 3.3E-196 T 12-10-2018 VAPA_1c33980 87c12739f66579f6b7a0f5b71e83d3a4 567 Pfam PF13450 NAD(P)-binding Rossmann-like domain 22 67 5.7E-7 T 12-10-2018 VAPA_1c33980 87c12739f66579f6b7a0f5b71e83d3a4 567 SUPERFAMILY SSF51905 14 463 3.58E-60 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c45650 cbf1d45da3a07f8e0a2984e999ef68d8 392 Gene3D G3DSA:2.60.40.420 130 272 1.1E-76 T 12-10-2018 IPR008972 Cupredoxin VAPA_1c45650 cbf1d45da3a07f8e0a2984e999ef68d8 392 PRINTS PR01166 Cytochrome c oxidase subunit II signature 108 128 5.3E-37 T 12-10-2018 VAPA_1c45650 cbf1d45da3a07f8e0a2984e999ef68d8 392 PRINTS PR01166 Cytochrome c oxidase subunit II signature 130 149 5.3E-37 T 12-10-2018 VAPA_1c45650 cbf1d45da3a07f8e0a2984e999ef68d8 392 PRINTS PR01166 Cytochrome c oxidase subunit II signature 227 244 5.3E-37 T 12-10-2018 VAPA_1c45650 cbf1d45da3a07f8e0a2984e999ef68d8 392 PRINTS PR01166 Cytochrome c oxidase subunit II signature 183 204 5.3E-37 T 12-10-2018 VAPA_1c45650 cbf1d45da3a07f8e0a2984e999ef68d8 392 PRINTS PR01166 Cytochrome c oxidase subunit II signature 96 108 5.3E-37 T 12-10-2018 VAPA_1c45650 cbf1d45da3a07f8e0a2984e999ef68d8 392 PRINTS PR01166 Cytochrome c oxidase subunit II signature 245 262 5.3E-37 T 12-10-2018 VAPA_1c45650 cbf1d45da3a07f8e0a2984e999ef68d8 392 PRINTS PR01166 Cytochrome c oxidase subunit II signature 207 227 5.3E-37 T 12-10-2018 VAPA_1c45650 cbf1d45da3a07f8e0a2984e999ef68d8 392 SUPERFAMILY SSF49503 128 320 3.95E-48 T 12-10-2018 IPR008972 Cupredoxin VAPA_1c45650 cbf1d45da3a07f8e0a2984e999ef68d8 392 Gene3D G3DSA:1.10.760.10 278 392 1.3E-24 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 VAPA_1c45650 cbf1d45da3a07f8e0a2984e999ef68d8 392 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 296 368 6.3E-12 T 12-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 VAPA_1c45650 cbf1d45da3a07f8e0a2984e999ef68d8 392 Pfam PF00116 Cytochrome C oxidase subunit II, periplasmic domain 134 263 2.5E-35 T 12-10-2018 IPR002429 Cytochrome c oxidase subunit II-like C-terminal GO:0004129|GO:0005507|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 VAPA_1c45650 cbf1d45da3a07f8e0a2984e999ef68d8 392 SUPERFAMILY SSF81464 36 127 2.78E-26 T 12-10-2018 IPR036257 Cytochrome C oxidase subunit II, transmembrane domain superfamily Reactome: R-HSA-5628897|Reactome: R-HSA-611105 VAPA_1c45650 cbf1d45da3a07f8e0a2984e999ef68d8 392 ProSitePatterns PS00078 CO II and nitrous oxide reductase dinuclear copper centers signature. 208 256 - T 12-10-2018 IPR001505 Copper centre Cu(A) GO:0005507 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 VAPA_1c45650 cbf1d45da3a07f8e0a2984e999ef68d8 392 Pfam PF02790 Cytochrome C oxidase subunit II, transmembrane domain 38 121 3.7E-14 T 12-10-2018 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 VAPA_1c45650 cbf1d45da3a07f8e0a2984e999ef68d8 392 SUPERFAMILY SSF46626 283 382 9.17E-21 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 VAPA_1c45650 cbf1d45da3a07f8e0a2984e999ef68d8 392 TIGRFAM TIGR02866 CoxB: cytochrome c oxidase, subunit II 48 272 8.7E-56 T 12-10-2018 IPR014222 Cytochrome c oxidase, subunit II GO:0016021|GO:0016491 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 VAPA_1c45650 cbf1d45da3a07f8e0a2984e999ef68d8 392 Gene3D G3DSA:1.10.287.90 58 129 1.1E-76 T 12-10-2018 IPR036257 Cytochrome C oxidase subunit II, transmembrane domain superfamily Reactome: R-HSA-5628897|Reactome: R-HSA-611105 VAPA_2c00390 5b3b661849739a1184dfe43464ce1c59 279 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 67 263 1.6E-23 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF VAPA_2c00390 5b3b661849739a1184dfe43464ce1c59 279 SUPERFAMILY SSF53850 51 266 8.16E-33 T 12-10-2018 VAPA_2c00390 5b3b661849739a1184dfe43464ce1c59 279 SMART SM00062 50 269 6.1E-28 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF VAPA_2c00390 5b3b661849739a1184dfe43464ce1c59 279 Gene3D G3DSA:3.40.190.10 136 228 3.8E-28 T 12-10-2018 VAPA_2c00390 5b3b661849739a1184dfe43464ce1c59 279 Gene3D G3DSA:3.40.190.10 47 258 3.8E-28 T 12-10-2018 VAPA_1c48300 05638c8befaedfb0f436839391b4043b 143 Gene3D G3DSA:3.90.1180.10 2 143 1.1E-57 T 12-10-2018 IPR036899 Ribosomal protein L13 superfamily GO:0003735|GO:0005840|GO:0006412 VAPA_1c48300 05638c8befaedfb0f436839391b4043b 143 SUPERFAMILY SSF52161 3 141 1.31E-56 T 12-10-2018 IPR036899 Ribosomal protein L13 superfamily GO:0003735|GO:0005840|GO:0006412 VAPA_1c48300 05638c8befaedfb0f436839391b4043b 143 PIRSF PIRSF002181 1 143 4.0E-47 T 12-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 VAPA_1c48300 05638c8befaedfb0f436839391b4043b 143 Pfam PF00572 Ribosomal protein L13 15 139 1.1E-52 T 12-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 VAPA_1c48300 05638c8befaedfb0f436839391b4043b 143 TIGRFAM TIGR01066 rplM_bact: ribosomal protein uL13 6 142 1.5E-59 T 12-10-2018 IPR005823 Ribosomal protein L13, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 VAPA_1c48300 05638c8befaedfb0f436839391b4043b 143 Hamap MF_01366 50S ribosomal protein L13 [rplM]. 16 142 26.823 T 12-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 VAPA_2c10580 d07eb322899a6e07598ae0036e02c9ed 181 Gene3D G3DSA:1.20.1260.10 8 180 3.0E-43 T 12-10-2018 IPR012347 Ferritin-like VAPA_2c10580 d07eb322899a6e07598ae0036e02c9ed 181 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 156 174 4.4E-8 T 12-10-2018 IPR002177 DNA-binding protein Dps VAPA_2c10580 d07eb322899a6e07598ae0036e02c9ed 181 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 84 100 4.4E-8 T 12-10-2018 IPR002177 DNA-binding protein Dps VAPA_2c10580 d07eb322899a6e07598ae0036e02c9ed 181 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 60 76 4.4E-8 T 12-10-2018 IPR002177 DNA-binding protein Dps VAPA_2c10580 d07eb322899a6e07598ae0036e02c9ed 181 SUPERFAMILY SSF47240 23 176 1.03E-44 T 12-10-2018 IPR009078 Ferritin-like superfamily VAPA_2c10580 d07eb322899a6e07598ae0036e02c9ed 181 Pfam PF00210 Ferritin-like domain 40 174 2.2E-22 T 12-10-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 VAPA_2c10580 d07eb322899a6e07598ae0036e02c9ed 181 PIRSF PIRSF005900 17 181 2.4E-45 T 12-10-2018 IPR002177 DNA-binding protein Dps VAPA_2c03430 abd92f3a73267e489678cc8962b17a5d 329 Pfam PF13602 Zinc-binding dehydrogenase 223 326 3.8E-6 T 12-10-2018 VAPA_2c03430 abd92f3a73267e489678cc8962b17a5d 329 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 26 132 9.3E-31 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 VAPA_2c03430 abd92f3a73267e489678cc8962b17a5d 329 Gene3D G3DSA:3.40.50.720 148 278 6.6E-83 T 12-10-2018 VAPA_2c03430 abd92f3a73267e489678cc8962b17a5d 329 Gene3D G3DSA:3.90.180.10 12 323 6.6E-83 T 12-10-2018 VAPA_2c03430 abd92f3a73267e489678cc8962b17a5d 329 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 59 73 - T 12-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 VAPA_2c03430 abd92f3a73267e489678cc8962b17a5d 329 SUPERFAMILY SSF50129 1 160 1.23E-45 T 12-10-2018 IPR011032 GroES-like superfamily VAPA_2c03430 abd92f3a73267e489678cc8962b17a5d 329 SUPERFAMILY SSF51735 140 297 1.75E-23 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_2c03430 abd92f3a73267e489678cc8962b17a5d 329 TIGRFAM TIGR02822 adh_fam_2: zinc-binding alcohol dehydrogenase family protein 12 328 9.5E-103 T 12-10-2018 IPR014187 Alcohol dehydrogenase, zinc-binding type 2 KEGG: 00010+1.1.1.1|KEGG: 00071+1.1.1.1|KEGG: 00260+1.1.1.1|KEGG: 00350+1.1.1.1|KEGG: 00592+1.1.1.1|KEGG: 00625+1.1.1.1|KEGG: 00626+1.1.1.1|KEGG: 00830+1.1.1.1|KEGG: 00980+1.1.1.1|KEGG: 00982+1.1.1.1|MetaCyc: PWY-3162|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5079|MetaCyc: PWY-5082|MetaCyc: PWY-5480|MetaCyc: PWY-5486|MetaCyc: PWY-5751|MetaCyc: PWY-6313|MetaCyc: PWY-6333|MetaCyc: PWY-6342|MetaCyc: PWY-6587|MetaCyc: PWY-6802|MetaCyc: PWY-6871|MetaCyc: PWY-7013|MetaCyc: PWY-7111|MetaCyc: PWY-7118|MetaCyc: PWY-7396 VAPA_1c00170 a35b56e6cd92a5f4c48b91912468a309 285 SUPERFAMILY SSF51182 8 284 6.38E-83 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily VAPA_1c00170 a35b56e6cd92a5f4c48b91912468a309 285 Gene3D G3DSA:2.60.120.10 18 279 4.2E-96 T 12-10-2018 IPR014710 RmlC-like jelly roll fold VAPA_1c00170 a35b56e6cd92a5f4c48b91912468a309 285 PIRSF PIRSF006232 3 285 1.2E-96 T 12-10-2018 IPR012093 Pirin Reactome: R-HSA-8935690 VAPA_1c00170 a35b56e6cd92a5f4c48b91912468a309 285 Gene3D G3DSA:2.60.120.10 144 253 4.2E-96 T 12-10-2018 IPR014710 RmlC-like jelly roll fold VAPA_1c00170 a35b56e6cd92a5f4c48b91912468a309 285 Pfam PF05726 Pirin C-terminal cupin domain 177 284 4.4E-30 T 12-10-2018 IPR008778 Pirin, C-terminal domain Reactome: R-HSA-8935690 VAPA_1c00170 a35b56e6cd92a5f4c48b91912468a309 285 Pfam PF02678 Pirin 22 122 6.6E-34 T 12-10-2018 IPR003829 Pirin, N-terminal domain Reactome: R-HSA-8935690 VAPA_1c13430 37dd2b5baa7c2307494f203da88cc28d 106 Gene3D G3DSA:3.30.10.10 40 105 4.1E-17 T 12-10-2018 VAPA_1c13430 37dd2b5baa7c2307494f203da88cc28d 106 Pfam PF11720 Peptidase inhibitor I78 family 42 106 2.2E-16 T 12-10-2018 IPR021719 Proteinase inhibitor I78 VAPA_1c50650 7c1351c4cff353532616086553e562af 522 Gene3D G3DSA:1.20.1250.20 9 258 2.2E-40 T 12-10-2018 VAPA_1c50650 7c1351c4cff353532616086553e562af 522 ProSitePatterns PS00216 Sugar transport proteins signature 1. 66 82 - T 12-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 VAPA_1c50650 7c1351c4cff353532616086553e562af 522 SUPERFAMILY SSF103473 10 507 1.83E-56 T 12-10-2018 IPR036259 MFS transporter superfamily VAPA_1c50650 7c1351c4cff353532616086553e562af 522 Gene3D G3DSA:1.20.1250.20 271 513 3.0E-10 T 12-10-2018 VAPA_1c50650 7c1351c4cff353532616086553e562af 522 Pfam PF07690 Major Facilitator Superfamily 16 405 8.4E-48 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 VAPA_1c25370 ecdfdc2c408537b18d697d0d1361b7ba 363 Gene3D G3DSA:3.50.50.60 9 344 2.3E-48 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c25370 ecdfdc2c408537b18d697d0d1361b7ba 363 Pfam PF01266 FAD dependent oxidoreductase 9 337 3.3E-30 T 12-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 VAPA_1c25370 ecdfdc2c408537b18d697d0d1361b7ba 363 Gene3D G3DSA:3.30.9.10 92 306 2.3E-48 T 12-10-2018 VAPA_1c25370 ecdfdc2c408537b18d697d0d1361b7ba 363 SUPERFAMILY SSF51971 8 346 1.53E-22 T 12-10-2018 VAPA_1c25370 ecdfdc2c408537b18d697d0d1361b7ba 363 SUPERFAMILY SSF54373 216 305 1.03E-15 T 12-10-2018 VAPA_2c00100 bf2a2391360f485694d79b401e4d09de 126 Gene3D G3DSA:3.40.50.1010 4 118 4.9E-8 T 12-10-2018 VAPA_2c00100 bf2a2391360f485694d79b401e4d09de 126 SUPERFAMILY SSF88723 4 119 4.21E-11 T 12-10-2018 IPR029060 PIN-like domain superfamily VAPA_2c01140 4a617ac2f1255a85b7f1900df6a4a48f 326 Gene3D G3DSA:3.40.190.10 132 251 2.6E-77 T 12-10-2018 VAPA_2c01140 4a617ac2f1255a85b7f1900df6a4a48f 326 PIRSF PIRSF017082 1 325 6.6E-78 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_2c01140 4a617ac2f1255a85b7f1900df6a4a48f 326 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 54 322 4.7E-61 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_2c01140 4a617ac2f1255a85b7f1900df6a4a48f 326 Gene3D G3DSA:3.40.190.150 35 313 2.6E-77 T 12-10-2018 VAPA_2c01140 4a617ac2f1255a85b7f1900df6a4a48f 326 SUPERFAMILY SSF53850 41 280 3.8E-9 T 12-10-2018 VAPA_2c02530 599f7996de7be8681547de0d6e44f0d6 483 Gene3D G3DSA:2.30.40.10 5 434 2.5E-184 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 VAPA_2c02530 599f7996de7be8681547de0d6e44f0d6 483 Gene3D G3DSA:3.20.20.140 58 415 2.5E-184 T 12-10-2018 VAPA_2c02530 599f7996de7be8681547de0d6e44f0d6 483 Gene3D G3DSA:3.30.1490.130 289 345 2.5E-184 T 12-10-2018 IPR023100 D-aminoacylase, insert domain superfamily GO:0016811 VAPA_2c02530 599f7996de7be8681547de0d6e44f0d6 483 Pfam PF07969 Amidohydrolase family 48 243 1.8E-15 T 12-10-2018 IPR013108 Amidohydrolase 3 VAPA_2c02530 599f7996de7be8681547de0d6e44f0d6 483 Pfam PF07969 Amidohydrolase family 361 464 1.7E-14 T 12-10-2018 IPR013108 Amidohydrolase 3 VAPA_2c02530 599f7996de7be8681547de0d6e44f0d6 483 SUPERFAMILY SSF51338 5 477 1.46E-19 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 VAPA_2c02530 599f7996de7be8681547de0d6e44f0d6 483 SUPERFAMILY SSF51556 59 420 1.33E-80 T 12-10-2018 IPR032466 Metal-dependent hydrolase VAPA_1c15580 1fd2d67918f1e7d77d58fb6d071a3342 233 Pfam PF00308 Bacterial dnaA protein 101 212 4.7E-7 T 12-10-2018 IPR013317 Chromosomal replication initiator protein DnaA VAPA_1c15580 1fd2d67918f1e7d77d58fb6d071a3342 233 Pfam PF00308 Bacterial dnaA protein 20 78 1.4E-4 T 12-10-2018 IPR013317 Chromosomal replication initiator protein DnaA VAPA_1c15580 1fd2d67918f1e7d77d58fb6d071a3342 233 TIGRFAM TIGR03420 DnaA_homol_Hda: DnaA regulatory inactivator Hda 8 231 4.5E-66 T 12-10-2018 IPR017788 DnaA regulatory inactivator Hda GO:0032297 VAPA_1c15580 1fd2d67918f1e7d77d58fb6d071a3342 233 Gene3D G3DSA:3.40.50.300 46 162 5.6E-21 T 12-10-2018 VAPA_1c15580 1fd2d67918f1e7d77d58fb6d071a3342 233 SUPERFAMILY SSF52540 29 215 1.64E-18 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c15580 1fd2d67918f1e7d77d58fb6d071a3342 233 Gene3D G3DSA:1.10.8.60 166 231 4.0E-23 T 12-10-2018 VAPA_1c19510 60061df9258f8c94a98d357e23672c9c 387 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 50 134 9.3E-10 T 12-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 VAPA_1c19510 60061df9258f8c94a98d357e23672c9c 387 SUPERFAMILY SSF55347 146 350 1.2E-26 T 12-10-2018 VAPA_1c19510 60061df9258f8c94a98d357e23672c9c 387 SUPERFAMILY SSF51735 50 173 2.51E-27 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c19510 60061df9258f8c94a98d357e23672c9c 387 Gene3D G3DSA:3.40.50.720 1 140 5.5E-40 T 12-10-2018 VAPA_1c19510 60061df9258f8c94a98d357e23672c9c 387 Gene3D G3DSA:3.30.360.10 141 385 4.8E-64 T 12-10-2018 VAPA_1c47850 6669708025f30f1e096da3a5b6b94cae 132 Pfam PF05025 RbsD / FucU transport protein family 2 131 7.8E-42 T 12-10-2018 IPR007721 D-ribose pyranase RbsD/L-fucose mutarotase FucU GO:0005996|GO:0016853|GO:0048029 Reactome: R-HSA-6787639 VAPA_1c47850 6669708025f30f1e096da3a5b6b94cae 132 Hamap MF_01661 D-ribose pyranase [rbsD]. 1 132 29.98 T 12-10-2018 IPR023064 D-ribose pyranase GO:0016872 VAPA_1c47850 6669708025f30f1e096da3a5b6b94cae 132 SUPERFAMILY SSF102546 2 132 2.88E-38 T 12-10-2018 IPR023750 RbsD-like superfamily GO:0005996|GO:0016853|GO:0048029 Reactome: R-HSA-6787639 VAPA_1c47850 6669708025f30f1e096da3a5b6b94cae 132 Gene3D G3DSA:3.40.1650.10 8 128 2.8E-32 T 12-10-2018 IPR023750 RbsD-like superfamily GO:0005996|GO:0016853|GO:0048029 Reactome: R-HSA-6787639 VAPA_1c51070 a8458db7540a0c5eb36a349d2aa79dea 142 Pfam PF03653 Uncharacterised protein family (UPF0093) 2 142 8.4E-43 T 12-10-2018 IPR005265 Uncharacterised protein family UPF0093 VAPA_1c51070 a8458db7540a0c5eb36a349d2aa79dea 142 PIRSF PIRSF004638 1 142 5.2E-48 T 12-10-2018 IPR005265 Uncharacterised protein family UPF0093 VAPA_1c02740 f5451101c184176c8d76dd580e9b13cb 297 Pfam PF13541 Subunit ChlI of Mg-chelatase 51 133 2.1E-22 T 12-10-2018 VAPA_1c02740 f5451101c184176c8d76dd580e9b13cb 297 Gene3D G3DSA:3.30.230.10 34 163 5.4E-5 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup VAPA_1c02740 f5451101c184176c8d76dd580e9b13cb 297 SUPERFAMILY SSF52540 195 287 5.42E-13 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c02740 f5451101c184176c8d76dd580e9b13cb 297 Gene3D G3DSA:3.40.50.300 187 265 1.6E-15 T 12-10-2018 VAPA_1c02740 f5451101c184176c8d76dd580e9b13cb 297 Pfam PF01078 Magnesium chelatase, subunit ChlI 195 290 1.3E-34 T 12-10-2018 IPR000523 Magnesium chelatase ChlI domain VAPA_1c02740 f5451101c184176c8d76dd580e9b13cb 297 SUPERFAMILY SSF54211 47 162 2.28E-19 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold VAPA_1c35230 df42d1f2bf6c8f32eacae4938b216996 251 SMART SM00382 31 218 9.8E-17 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c35230 df42d1f2bf6c8f32eacae4938b216996 251 Pfam PF00005 ABC transporter 22 170 2.5E-37 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c35230 df42d1f2bf6c8f32eacae4938b216996 251 SUPERFAMILY SSF52540 6 240 4.31E-81 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c35230 df42d1f2bf6c8f32eacae4938b216996 251 PIRSF PIRSF039085 3 246 2.4E-108 T 12-10-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 VAPA_1c35230 df42d1f2bf6c8f32eacae4938b216996 251 Gene3D G3DSA:3.40.50.300 2 248 1.3E-79 T 12-10-2018 VAPA_1c35230 df42d1f2bf6c8f32eacae4938b216996 251 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_1c53710 4f0ceb983e10904baef6bb8a10edc5f3 203 Pfam PF12019 Type II transport protein GspH 46 183 1.5E-10 T 12-10-2018 IPR022346 General secretion pathway, GspH GO:0008565|GO:0015627|GO:0015628 VAPA_1c53710 4f0ceb983e10904baef6bb8a10edc5f3 203 Pfam PF07963 Prokaryotic N-terminal methylation motif 5 29 2.3E-7 T 12-10-2018 IPR012902 Prokaryotic N-terminal methylation site VAPA_1c53710 4f0ceb983e10904baef6bb8a10edc5f3 203 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 7 29 7.1E-7 T 12-10-2018 IPR012902 Prokaryotic N-terminal methylation site VAPA_1c53710 4f0ceb983e10904baef6bb8a10edc5f3 203 SUPERFAMILY SSF54523 10 130 7.69E-13 T 12-10-2018 VAPA_1c53710 4f0ceb983e10904baef6bb8a10edc5f3 203 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 8 28 - T 12-10-2018 IPR012902 Prokaryotic N-terminal methylation site VAPA_1c53710 4f0ceb983e10904baef6bb8a10edc5f3 203 Gene3D G3DSA:3.30.700.10 10 203 1.4E-9 T 12-10-2018 VAPA_1c24600 097f41859d7e72e573e4b0d5abd77689 89 SUPERFAMILY SSF143800 3 82 7.06E-19 T 12-10-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 VAPA_1c24600 097f41859d7e72e573e4b0d5abd77689 89 PRINTS PR01249 Ribosomal protein L31 signature 46 61 1.9E-7 T 12-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 VAPA_1c24600 097f41859d7e72e573e4b0d5abd77689 89 PRINTS PR01249 Ribosomal protein L31 signature 3 20 1.9E-7 T 12-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 VAPA_1c24600 097f41859d7e72e573e4b0d5abd77689 89 TIGRFAM TIGR00105 L31: ribosomal protein bL31 3 82 5.5E-19 T 12-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 VAPA_1c24600 097f41859d7e72e573e4b0d5abd77689 89 ProSitePatterns PS01143 Ribosomal protein L31 signature. 50 72 - T 12-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 VAPA_1c24600 097f41859d7e72e573e4b0d5abd77689 89 Pfam PF01197 Ribosomal protein L31 3 81 3.1E-25 T 12-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 VAPA_1c24600 097f41859d7e72e573e4b0d5abd77689 89 Gene3D G3DSA:2.30.170.50 2 85 1.2E-20 T 12-10-2018 VAPA_1c48510 06a8ca7bb5686cd5305c04a44aff6daa 342 Pfam PF13416 Bacterial extracellular solute-binding protein 47 303 1.2E-44 T 12-10-2018 IPR006059 Bacterial extracellular solute-binding protein VAPA_1c48510 06a8ca7bb5686cd5305c04a44aff6daa 342 Gene3D G3DSA:3.40.190.10 125 327 8.6E-119 T 12-10-2018 VAPA_1c48510 06a8ca7bb5686cd5305c04a44aff6daa 342 Gene3D G3DSA:3.40.190.10 26 320 8.6E-119 T 12-10-2018 VAPA_1c48510 06a8ca7bb5686cd5305c04a44aff6daa 342 SUPERFAMILY SSF53850 21 339 1.04E-66 T 12-10-2018 VAPA_1c32400 a3e03d4e538a80466e60d587f7889b54 257 SUPERFAMILY SSF46689 201 250 1.84E-11 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 VAPA_1c32400 a3e03d4e538a80466e60d587f7889b54 257 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 202 244 - T 12-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 VAPA_1c32400 a3e03d4e538a80466e60d587f7889b54 257 SUPERFAMILY SSF46689 148 198 4.9E-8 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 VAPA_1c32400 a3e03d4e538a80466e60d587f7889b54 257 Pfam PF12833 Helix-turn-helix domain 171 249 3.7E-20 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 VAPA_1c32400 a3e03d4e538a80466e60d587f7889b54 257 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 217 232 1.4E-5 T 12-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 VAPA_1c32400 a3e03d4e538a80466e60d587f7889b54 257 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 232 248 1.4E-5 T 12-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 VAPA_1c32400 a3e03d4e538a80466e60d587f7889b54 257 Gene3D G3DSA:1.10.10.60 145 255 7.3E-28 T 12-10-2018 VAPA_1c32400 a3e03d4e538a80466e60d587f7889b54 257 SMART SM00342 165 248 9.3E-27 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 VAPA_1c22850 2c99f1b02eaafb5637fcd5417c65ed60 313 Gene3D G3DSA:3.30.360.10 133 297 5.3E-127 T 12-10-2018 VAPA_1c22850 2c99f1b02eaafb5637fcd5417c65ed60 313 TIGRFAM TIGR03215 ac_ald_DH_ac: acetaldehyde dehydrogenase (acetylating) 5 308 5.4E-139 T 12-10-2018 IPR003361 Acetaldehyde dehydrogenase GO:0008774|GO:0019439|GO:0055114 KEGG: 00360+1.2.1.10|KEGG: 00362+1.2.1.10|KEGG: 00620+1.2.1.10|KEGG: 00621+1.2.1.10|KEGG: 00622+1.2.1.10|KEGG: 00650+1.2.1.10|MetaCyc: PWY-5162|MetaCyc: PWY-5436|MetaCyc: PWY-5480|MetaCyc: PWY-6587|MetaCyc: PWY-7085|MetaCyc: PWY-7180 VAPA_1c22850 2c99f1b02eaafb5637fcd5417c65ed60 313 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 7 122 2.7E-9 T 12-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 VAPA_1c22850 2c99f1b02eaafb5637fcd5417c65ed60 313 Hamap MF_01657 Acetaldehyde dehydrogenase [mhpF]. 1 313 144.6 T 12-10-2018 IPR003361 Acetaldehyde dehydrogenase GO:0008774|GO:0019439|GO:0055114 KEGG: 00360+1.2.1.10|KEGG: 00362+1.2.1.10|KEGG: 00620+1.2.1.10|KEGG: 00621+1.2.1.10|KEGG: 00622+1.2.1.10|KEGG: 00650+1.2.1.10|MetaCyc: PWY-5162|MetaCyc: PWY-5436|MetaCyc: PWY-5480|MetaCyc: PWY-6587|MetaCyc: PWY-7085|MetaCyc: PWY-7180 VAPA_1c22850 2c99f1b02eaafb5637fcd5417c65ed60 313 Gene3D G3DSA:3.40.50.720 6 304 5.3E-127 T 12-10-2018 VAPA_1c22850 2c99f1b02eaafb5637fcd5417c65ed60 313 PIRSF PIRSF015689 2 313 7.5E-131 T 12-10-2018 IPR003361 Acetaldehyde dehydrogenase GO:0008774|GO:0019439|GO:0055114 KEGG: 00360+1.2.1.10|KEGG: 00362+1.2.1.10|KEGG: 00620+1.2.1.10|KEGG: 00621+1.2.1.10|KEGG: 00622+1.2.1.10|KEGG: 00650+1.2.1.10|MetaCyc: PWY-5162|MetaCyc: PWY-5436|MetaCyc: PWY-5480|MetaCyc: PWY-6587|MetaCyc: PWY-7085|MetaCyc: PWY-7180 VAPA_1c22850 2c99f1b02eaafb5637fcd5417c65ed60 313 SUPERFAMILY SSF51735 4 157 2.72E-28 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c22850 2c99f1b02eaafb5637fcd5417c65ed60 313 SMART SM00859 7 125 7.2E-12 T 12-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 VAPA_1c22850 2c99f1b02eaafb5637fcd5417c65ed60 313 SUPERFAMILY SSF55347 133 283 1.96E-62 T 12-10-2018 VAPA_1c22850 2c99f1b02eaafb5637fcd5417c65ed60 313 Pfam PF09290 Prokaryotic acetaldehyde dehydrogenase, dimerisation 133 283 3.5E-63 T 12-10-2018 IPR015426 Acetaldehyde dehydrogenase, C-terminal GO:0008774|GO:0019439|GO:0055114 KEGG: 00360+1.2.1.10|KEGG: 00362+1.2.1.10|KEGG: 00620+1.2.1.10|KEGG: 00621+1.2.1.10|KEGG: 00622+1.2.1.10|KEGG: 00650+1.2.1.10|MetaCyc: PWY-5162|MetaCyc: PWY-5436|MetaCyc: PWY-5480|MetaCyc: PWY-6587|MetaCyc: PWY-7085|MetaCyc: PWY-7180 VAPA_2c01960 7caeb4ba12e095a5e8f3841a68ace0ea 445 Gene3D G3DSA:1.20.1250.20 15 430 8.6E-65 T 12-10-2018 VAPA_2c01960 7caeb4ba12e095a5e8f3841a68ace0ea 445 ProSitePatterns PS00217 Sugar transport proteins signature 2. 117 142 - T 12-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 VAPA_2c01960 7caeb4ba12e095a5e8f3841a68ace0ea 445 SUPERFAMILY SSF103473 7 433 3.27E-71 T 12-10-2018 IPR036259 MFS transporter superfamily VAPA_2c01960 7caeb4ba12e095a5e8f3841a68ace0ea 445 Pfam PF07690 Major Facilitator Superfamily 24 361 2.9E-35 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 VAPA_1c16030 e7a6748a66ad742f931afc691b1f9ac9 175 SUPERFAMILY SSF46785 27 164 4.83E-29 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c16030 e7a6748a66ad742f931afc691b1f9ac9 175 SMART SM00347 50 151 1.1E-22 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 VAPA_1c16030 e7a6748a66ad742f931afc691b1f9ac9 175 Pfam PF01047 MarR family 57 115 2.3E-10 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 VAPA_1c16030 e7a6748a66ad742f931afc691b1f9ac9 175 ProSitePatterns PS01117 MarR-type HTH domain signature. 90 124 - T 12-10-2018 IPR023187 Transcriptional regulator MarR-type, conserved site VAPA_1c16030 e7a6748a66ad742f931afc691b1f9ac9 175 Gene3D G3DSA:1.10.10.10 15 165 3.6E-34 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c12460 c925dff89322038491a1b9a5a41a0989 143 Pfam PF01741 Large-conductance mechanosensitive channel, MscL 4 141 3.8E-43 T 12-10-2018 IPR037673 Large-conductance mechanosensitive channel/anditomin synthesis protein L VAPA_1c12460 c925dff89322038491a1b9a5a41a0989 143 ProSitePatterns PS01327 Large-conductance mechanosensitive channels mscL family signature. 13 26 - T 12-10-2018 IPR019823 Large-conductance mechanosensitive channel, conserved site VAPA_1c12460 c925dff89322038491a1b9a5a41a0989 143 Hamap MF_00115 Large-conductance mechanosensitive channel [mscL]. 3 142 23.858 T 12-10-2018 IPR001185 Large-conductance mechanosensitive channel GO:0008381|GO:0016021|GO:0034220 VAPA_1c12460 c925dff89322038491a1b9a5a41a0989 143 SUPERFAMILY SSF81330 13 137 1.44E-34 T 12-10-2018 IPR036019 Gated mechanosensitive channel VAPA_1c12460 c925dff89322038491a1b9a5a41a0989 143 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 103 112 2.3E-12 T 12-10-2018 IPR001185 Large-conductance mechanosensitive channel GO:0008381|GO:0016021|GO:0034220 VAPA_1c12460 c925dff89322038491a1b9a5a41a0989 143 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 94 102 2.3E-12 T 12-10-2018 IPR001185 Large-conductance mechanosensitive channel GO:0008381|GO:0016021|GO:0034220 VAPA_1c12460 c925dff89322038491a1b9a5a41a0989 143 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 6 20 2.3E-12 T 12-10-2018 IPR001185 Large-conductance mechanosensitive channel GO:0008381|GO:0016021|GO:0034220 VAPA_1c12460 c925dff89322038491a1b9a5a41a0989 143 Gene3D G3DSA:1.10.1200.120 3 143 1.2E-40 T 12-10-2018 IPR036019 Gated mechanosensitive channel VAPA_1c12460 c925dff89322038491a1b9a5a41a0989 143 TIGRFAM TIGR00220 mscL: large conductance mechanosensitive channel protein 4 141 1.4E-39 T 12-10-2018 IPR001185 Large-conductance mechanosensitive channel GO:0008381|GO:0016021|GO:0034220 VAPA_1c35070 d997b913ceaca4fa31289fa47c3799a6 583 ProSitePatterns PS00941 Carboxylesterases type-B signature 2. 117 127 - T 12-10-2018 IPR019819 Carboxylesterase type B, conserved site VAPA_1c35070 d997b913ceaca4fa31289fa47c3799a6 583 Gene3D G3DSA:3.40.50.1820 13 552 5.5E-109 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c35070 d997b913ceaca4fa31289fa47c3799a6 583 ProSitePatterns PS00122 Carboxylesterases type-B serine active site. 217 232 - T 12-10-2018 IPR019826 Carboxylesterase type B, active site VAPA_1c35070 d997b913ceaca4fa31289fa47c3799a6 583 SUPERFAMILY SSF53474 36 520 7.37E-90 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c35070 d997b913ceaca4fa31289fa47c3799a6 583 Pfam PF00135 Carboxylesterase family 40 519 2.2E-84 T 12-10-2018 IPR002018 Carboxylesterase, type B VAPA_1c40800 6e62fca57a1a70560ecc08b506d811f2 495 Pfam PF00860 Permease family 20 169 8.6E-35 T 12-10-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0016020|GO:0022857|GO:0055085 VAPA_1c40800 6e62fca57a1a70560ecc08b506d811f2 495 Pfam PF00860 Permease family 209 439 2.9E-67 T 12-10-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0016020|GO:0022857|GO:0055085 VAPA_1c40800 6e62fca57a1a70560ecc08b506d811f2 495 TIGRFAM TIGR00801 ncs2: uracil-xanthine permease 15 473 5.0E-114 T 12-10-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 VAPA_1c19310 31d7d1366b627d96ea62c77bada55e98 286 SMART SM00382 42 243 2.5E-10 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c19310 31d7d1366b627d96ea62c77bada55e98 286 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 244 266 6.3E-12 T 12-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal VAPA_1c19310 31d7d1366b627d96ea62c77bada55e98 286 SUPERFAMILY SSF52540 17 266 5.52E-61 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c19310 31d7d1366b627d96ea62c77bada55e98 286 Gene3D G3DSA:3.40.50.300 14 268 3.1E-59 T 12-10-2018 VAPA_1c19310 31d7d1366b627d96ea62c77bada55e98 286 Pfam PF00005 ABC transporter 33 195 9.2E-26 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c15460 8a0326fbc93bb8a5795dc3b6ee6bb97b 106 Gene3D G3DSA:3.30.70.2340 2 101 1.5E-35 T 12-10-2018 VAPA_1c15460 8a0326fbc93bb8a5795dc3b6ee6bb97b 106 Pfam PF12112 Protein of unknown function (DUF3579) 6 95 1.7E-39 T 12-10-2018 IPR021969 Protein of unknown function DUF3579 VAPA_1c31540 0d0bd105d9245f9cc927c10332909ba8 422 ProSitePatterns PS00324 Aspartokinase signature. 5 13 - T 12-10-2018 IPR018042 Aspartate kinase, conserved site GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 VAPA_1c31540 0d0bd105d9245f9cc927c10332909ba8 422 SUPERFAMILY SSF53633 4 254 1.03E-73 T 12-10-2018 IPR036393 Acetylglutamate kinase-like superfamily VAPA_1c31540 0d0bd105d9245f9cc927c10332909ba8 422 Pfam PF01842 ACT domain 280 336 2.4E-7 T 12-10-2018 IPR002912 ACT domain VAPA_1c31540 0d0bd105d9245f9cc927c10332909ba8 422 Gene3D G3DSA:3.40.1160.10 1 267 2.2E-83 T 12-10-2018 IPR036393 Acetylglutamate kinase-like superfamily VAPA_1c31540 0d0bd105d9245f9cc927c10332909ba8 422 SUPERFAMILY SSF55021 261 339 6.03E-18 T 12-10-2018 VAPA_1c31540 0d0bd105d9245f9cc927c10332909ba8 422 Gene3D G3DSA:3.30.70.260 274 352 6.0E-57 T 12-10-2018 VAPA_1c31540 0d0bd105d9245f9cc927c10332909ba8 422 Pfam PF00696 Amino acid kinase family 3 233 3.3E-51 T 12-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 VAPA_1c31540 0d0bd105d9245f9cc927c10332909ba8 422 TIGRFAM TIGR00656 asp_kin_monofn: aspartate kinase, monofunctional class 1 417 1.3E-124 T 12-10-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 VAPA_1c31540 0d0bd105d9245f9cc927c10332909ba8 422 Pfam PF13840 ACT domain 354 413 1.6E-15 T 12-10-2018 IPR027795 CASTOR, ACT domain VAPA_1c31540 0d0bd105d9245f9cc927c10332909ba8 422 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 67 415 6.5E-114 T 12-10-2018 IPR001341 Aspartate kinase GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 VAPA_1c31540 0d0bd105d9245f9cc927c10332909ba8 422 SUPERFAMILY SSF55021 340 418 1.58E-24 T 12-10-2018 VAPA_1c31540 0d0bd105d9245f9cc927c10332909ba8 422 PIRSF PIRSF000726 61 422 1.2E-136 T 12-10-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 VAPA_1c31540 0d0bd105d9245f9cc927c10332909ba8 422 PIRSF PIRSF000726 1 64 2.7E-20 T 12-10-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 VAPA_1c31540 0d0bd105d9245f9cc927c10332909ba8 422 Gene3D G3DSA:3.30.70.260 268 417 6.0E-57 T 12-10-2018 VAPA_2c10100 8eae404d9a02ed1ba1e2d33b96379f52 381 Gene3D G3DSA:2.40.37.20 11 372 1.5E-128 T 12-10-2018 VAPA_2c10100 8eae404d9a02ed1ba1e2d33b96379f52 381 SMART SM01119 259 367 4.5E-40 T 12-10-2018 IPR026956 D-serine dehydratase-like domain VAPA_2c10100 8eae404d9a02ed1ba1e2d33b96379f52 381 Pfam PF14031 Putative serine dehydratase domain 259 363 4.2E-20 T 12-10-2018 IPR026956 D-serine dehydratase-like domain VAPA_2c10100 8eae404d9a02ed1ba1e2d33b96379f52 381 SUPERFAMILY SSF51419 18 253 3.66E-37 T 12-10-2018 IPR029066 PLP-binding barrel VAPA_2c10100 8eae404d9a02ed1ba1e2d33b96379f52 381 Gene3D G3DSA:3.20.20.10 20 241 1.5E-128 T 12-10-2018 IPR029066 PLP-binding barrel VAPA_2c10100 8eae404d9a02ed1ba1e2d33b96379f52 381 Pfam PF01168 Alanine racemase, N-terminal domain 18 244 6.3E-35 T 12-10-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 VAPA_2c05230 f4d1189fe15ffaf81c78f764c60b6af6 271 Pfam PF00005 ABC transporter 28 169 1.2E-29 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_2c05230 f4d1189fe15ffaf81c78f764c60b6af6 271 Gene3D G3DSA:3.40.50.300 8 267 6.9E-65 T 12-10-2018 VAPA_2c05230 f4d1189fe15ffaf81c78f764c60b6af6 271 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_2c05230 f4d1189fe15ffaf81c78f764c60b6af6 271 SMART SM00382 37 218 8.2E-17 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_2c05230 f4d1189fe15ffaf81c78f764c60b6af6 271 SUPERFAMILY SSF52540 9 238 5.87E-65 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_2c06530 787a530d33222f732724cc8b784cb680 455 Pfam PF00072 Response regulator receiver domain 9 118 1.5E-24 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_2c06530 787a530d33222f732724cc8b784cb680 455 SUPERFAMILY SSF46689 396 447 6.27E-9 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 VAPA_2c06530 787a530d33222f732724cc8b784cb680 455 Pfam PF00158 Sigma-54 interaction domain 148 314 4.2E-64 T 12-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 VAPA_2c06530 787a530d33222f732724cc8b784cb680 455 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 411 428 3.5E-6 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 VAPA_2c06530 787a530d33222f732724cc8b784cb680 455 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 428 448 3.5E-6 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 VAPA_2c06530 787a530d33222f732724cc8b784cb680 455 Gene3D G3DSA:3.40.50.300 138 318 1.5E-59 T 12-10-2018 VAPA_2c06530 787a530d33222f732724cc8b784cb680 455 SMART SM00448 7 118 1.4E-30 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_2c06530 787a530d33222f732724cc8b784cb680 455 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 172 185 - T 12-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 VAPA_2c06530 787a530d33222f732724cc8b784cb680 455 Gene3D G3DSA:1.10.8.60 319 384 9.0E-19 T 12-10-2018 VAPA_2c06530 787a530d33222f732724cc8b784cb680 455 SUPERFAMILY SSF52172 7 193 5.41E-43 T 12-10-2018 IPR011006 CheY-like superfamily VAPA_2c06530 787a530d33222f732724cc8b784cb680 455 SUPERFAMILY SSF52540 148 384 4.5E-64 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_2c06530 787a530d33222f732724cc8b784cb680 455 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 361 370 - T 12-10-2018 IPR025944 Sigma-54 interaction domain, conserved site VAPA_2c06530 787a530d33222f732724cc8b784cb680 455 Gene3D G3DSA:1.10.10.60 398 450 2.3E-12 T 12-10-2018 VAPA_2c06530 787a530d33222f732724cc8b784cb680 455 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 234 249 - T 12-10-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 VAPA_2c06530 787a530d33222f732724cc8b784cb680 455 SMART SM00382 168 311 5.8E-8 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_2c06530 787a530d33222f732724cc8b784cb680 455 Gene3D G3DSA:3.40.50.2300 3 132 3.0E-33 T 12-10-2018 VAPA_2c06530 787a530d33222f732724cc8b784cb680 455 Pfam PF02954 Bacterial regulatory protein, Fis family 405 445 2.8E-8 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 VAPA_1c20740 9dfa50d45c7165ec1c5818fa623ef434 256 SUPERFAMILY SSF159270 43 244 1.44E-36 T 12-10-2018 IPR023373 YmcC-like superfamily VAPA_1c20740 9dfa50d45c7165ec1c5818fa623ef434 256 Gene3D G3DSA:2.40.360.10 66 205 2.2E-11 T 12-10-2018 IPR023373 YmcC-like superfamily VAPA_1c20740 9dfa50d45c7165ec1c5818fa623ef434 256 Pfam PF11102 Group 4 capsule polysaccharide lipoprotein gfcB, YjbF 35 196 1.8E-17 T 12-10-2018 IPR021308 Group 4 capsule polysaccharide formation lipoprotein GfcB VAPA_1c38220 e485dc67714624121e662db2c30cf7d9 181 Pfam PF03061 Thioesterase superfamily 88 165 4.0E-13 T 12-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 VAPA_1c38220 e485dc67714624121e662db2c30cf7d9 181 Gene3D G3DSA:3.10.129.10 38 178 3.6E-37 T 12-10-2018 VAPA_1c38220 e485dc67714624121e662db2c30cf7d9 181 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 57 173 8.9E-22 T 12-10-2018 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-77289 VAPA_1c38220 e485dc67714624121e662db2c30cf7d9 181 SUPERFAMILY SSF54637 5 173 2.67E-35 T 12-10-2018 IPR029069 HotDog domain superfamily VAPA_1c52330 a52cfedd6175893e843671cab5195850 541 Gene3D G3DSA:3.30.300.310 436 540 4.3E-27 T 12-10-2018 VAPA_1c52330 a52cfedd6175893e843671cab5195850 541 Pfam PF00501 AMP-binding enzyme 47 440 1.4E-71 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 VAPA_1c52330 a52cfedd6175893e843671cab5195850 541 SUPERFAMILY SSF56801 26 536 4.58E-125 T 12-10-2018 VAPA_1c52330 a52cfedd6175893e843671cab5195850 541 ProSitePatterns PS00455 Putative AMP-binding domain signature. 198 209 - T 12-10-2018 IPR020845 AMP-binding, conserved site VAPA_1c52330 a52cfedd6175893e843671cab5195850 541 Gene3D G3DSA:3.40.50.12780 30 433 1.4E-90 T 12-10-2018 VAPA_1c52330 a52cfedd6175893e843671cab5195850 541 Pfam PF13193 AMP-binding enzyme C-terminal domain 449 527 2.0E-22 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain VAPA_1c07380 09739dbd1212a4be9e19c70f14f6bbf6 143 SUPERFAMILY SSF46906 68 141 1.09E-25 T 12-10-2018 IPR036769 Ribosomal protein L11, C-terminal domain superfamily VAPA_1c07380 09739dbd1212a4be9e19c70f14f6bbf6 143 TIGRFAM TIGR01632 L11_bact: ribosomal protein uL11 3 141 6.7E-64 T 12-10-2018 IPR006519 Ribosomal protein L11, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 VAPA_1c07380 09739dbd1212a4be9e19c70f14f6bbf6 143 Pfam PF03946 Ribosomal protein L11, N-terminal domain 9 67 3.5E-28 T 12-10-2018 IPR020784 Ribosomal protein L11, N-terminal VAPA_1c07380 09739dbd1212a4be9e19c70f14f6bbf6 143 ProSitePatterns PS00359 Ribosomal protein L11 signature. 127 142 - T 12-10-2018 IPR020785 Ribosomal protein L11, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VAPA_1c07380 09739dbd1212a4be9e19c70f14f6bbf6 143 ProDom PD001367 RIBOSOMAL RIBONUCLEOPROTEIN L11 RRNA-BINDING RNA-BINDING METHYLATION 50S L11 BACTERIAL CHLOROPLAST 36 74 2.0E-15 T 12-10-2018 VAPA_1c07380 09739dbd1212a4be9e19c70f14f6bbf6 143 Pfam PF00298 Ribosomal protein L11, RNA binding domain 72 140 8.3E-24 T 12-10-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 VAPA_1c07380 09739dbd1212a4be9e19c70f14f6bbf6 143 Gene3D G3DSA:3.30.1550.10 2 72 1.9E-34 T 12-10-2018 IPR036796 Ribosomal protein L11/L12, N-terminal domain superfamily VAPA_1c07380 09739dbd1212a4be9e19c70f14f6bbf6 143 SMART SM00649 9 141 5.6E-83 T 12-10-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 VAPA_1c07380 09739dbd1212a4be9e19c70f14f6bbf6 143 Gene3D G3DSA:1.10.10.250 73 141 2.3E-27 T 12-10-2018 IPR036769 Ribosomal protein L11, C-terminal domain superfamily VAPA_1c07380 09739dbd1212a4be9e19c70f14f6bbf6 143 SUPERFAMILY SSF54747 3 73 5.23E-30 T 12-10-2018 IPR036796 Ribosomal protein L11/L12, N-terminal domain superfamily VAPA_1c07380 09739dbd1212a4be9e19c70f14f6bbf6 143 Hamap MF_00736 50S ribosomal protein L11 [rplK]. 5 142 31.403 T 12-10-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 VAPA_1c09620 f6599f6c4a6fae405e5ff0dcd3678403 442 SUPERFAMILY SSF52540 3 440 5.82E-87 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c09620 f6599f6c4a6fae405e5ff0dcd3678403 442 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 334 403 5.6E-5 T 12-10-2018 IPR019489 Clp ATPase, C-terminal VAPA_1c09620 f6599f6c4a6fae405e5ff0dcd3678403 442 Hamap MF_00249 ATP-dependent protease ATPase subunit HslU [hslU]. 1 442 41.609 T 12-10-2018 IPR004491 Heat shock protein HslU GO:0005524|GO:0005737|GO:0009376|GO:0016887|GO:0070011 VAPA_1c09620 f6599f6c4a6fae405e5ff0dcd3678403 442 SMART SM01086 334 430 8.6E-22 T 12-10-2018 IPR019489 Clp ATPase, C-terminal VAPA_1c09620 f6599f6c4a6fae405e5ff0dcd3678403 442 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 52 101 3.0E-6 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 VAPA_1c09620 f6599f6c4a6fae405e5ff0dcd3678403 442 Pfam PF07724 AAA domain (Cdc48 subfamily) 184 328 6.5E-40 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 VAPA_1c09620 f6599f6c4a6fae405e5ff0dcd3678403 442 Gene3D G3DSA:1.10.8.60 334 439 1.1E-36 T 12-10-2018 VAPA_1c09620 f6599f6c4a6fae405e5ff0dcd3678403 442 TIGRFAM TIGR00390 hslU: ATP-dependent protease HslVU, ATPase subunit 3 442 3.8E-201 T 12-10-2018 IPR004491 Heat shock protein HslU GO:0005524|GO:0005737|GO:0009376|GO:0016887|GO:0070011 VAPA_1c09620 f6599f6c4a6fae405e5ff0dcd3678403 442 SMART SM00382 48 335 2.0E-12 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c42360 245809c9c6c3c141f94e9bd3162ca2b6 223 SMART SM00895 84 208 1.2E-17 T 12-10-2018 IPR011711 GntR, C-terminal VAPA_1c42360 245809c9c6c3c141f94e9bd3162ca2b6 223 SMART SM00345 16 74 8.3E-15 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_1c42360 245809c9c6c3c141f94e9bd3162ca2b6 223 SUPERFAMILY SSF46785 8 98 3.71E-18 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c42360 245809c9c6c3c141f94e9bd3162ca2b6 223 Gene3D G3DSA:1.10.10.10 8 75 5.0E-21 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c42360 245809c9c6c3c141f94e9bd3162ca2b6 223 Pfam PF07729 FCD domain 85 206 1.6E-25 T 12-10-2018 IPR011711 GntR, C-terminal VAPA_1c42360 245809c9c6c3c141f94e9bd3162ca2b6 223 Gene3D G3DSA:1.20.120.530 79 211 1.1E-27 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal VAPA_1c42360 245809c9c6c3c141f94e9bd3162ca2b6 223 Pfam PF00392 Bacterial regulatory proteins, gntR family 12 74 3.1E-18 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_1c42360 245809c9c6c3c141f94e9bd3162ca2b6 223 SUPERFAMILY SSF48008 81 209 2.09E-25 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal VAPA_1c12310 efc1a03551db37bcd96404753d977374 305 SMART SM00062 47 278 4.3E-60 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF VAPA_1c12310 efc1a03551db37bcd96404753d977374 305 Gene3D G3DSA:3.40.190.10 140 235 4.5E-93 T 12-10-2018 VAPA_1c12310 efc1a03551db37bcd96404753d977374 305 Gene3D G3DSA:3.40.190.10 37 280 4.5E-93 T 12-10-2018 VAPA_1c12310 efc1a03551db37bcd96404753d977374 305 SUPERFAMILY SSF53850 14 278 4.82E-64 T 12-10-2018 VAPA_1c12310 efc1a03551db37bcd96404753d977374 305 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 48 275 5.0E-51 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF VAPA_1c04960 28f4d7e3657842cceb6445a6f7251cf8 556 SUPERFAMILY SSF51445 10 470 2.05E-125 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily VAPA_1c04960 28f4d7e3657842cceb6445a6f7251cf8 556 SMART SM00642 19 411 3.5E-113 T 12-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 VAPA_1c04960 28f4d7e3657842cceb6445a6f7251cf8 556 Gene3D G3DSA:3.20.20.80 11 465 3.8E-169 T 12-10-2018 VAPA_1c04960 28f4d7e3657842cceb6445a6f7251cf8 556 SUPERFAMILY SSF51011 473 548 5.96E-8 T 12-10-2018 VAPA_1c04960 28f4d7e3657842cceb6445a6f7251cf8 556 Gene3D G3DSA:3.90.400.10 111 181 3.8E-169 T 12-10-2018 VAPA_1c04960 28f4d7e3657842cceb6445a6f7251cf8 556 Pfam PF00128 Alpha amylase, catalytic domain 34 386 1.9E-83 T 12-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 VAPA_1c35740 8d50fad2fd5654c4348155df544b56b8 629 Gene3D G3DSA:3.30.565.10 15 222 1.8E-59 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_1c35740 8d50fad2fd5654c4348155df544b56b8 629 SUPERFAMILY SSF54211 199 336 1.02E-35 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold VAPA_1c35740 8d50fad2fd5654c4348155df544b56b8 629 Pfam PF13589 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 37 132 1.5E-11 T 12-10-2018 VAPA_1c35740 8d50fad2fd5654c4348155df544b56b8 629 ProSitePatterns PS00058 DNA mismatch repair proteins mutL / hexB / PMS1 signature. 106 112 - T 12-10-2018 IPR014762 DNA mismatch repair, conserved site VAPA_1c35740 8d50fad2fd5654c4348155df544b56b8 629 Gene3D G3DSA:3.30.230.10 223 335 4.1E-35 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup VAPA_1c35740 8d50fad2fd5654c4348155df544b56b8 629 TIGRFAM TIGR00585 mutl: DNA mismatch repair protein MutL 15 316 1.6E-87 T 12-10-2018 IPR002099 DNA mismatch repair protein family, N-terminal GO:0005524|GO:0006298|GO:0030983 VAPA_1c35740 8d50fad2fd5654c4348155df544b56b8 629 Pfam PF01119 DNA mismatch repair protein, C-terminal domain 220 335 6.8E-36 T 12-10-2018 IPR013507 DNA mismatch repair protein, S5 domain 2-like GO:0005524|GO:0006298|GO:0030983 VAPA_1c35740 8d50fad2fd5654c4348155df544b56b8 629 SUPERFAMILY SSF118116 437 627 6.41E-58 T 12-10-2018 IPR037198 MutL, C-terminal domain superfamily VAPA_1c35740 8d50fad2fd5654c4348155df544b56b8 629 SMART SM00853 442 585 7.0E-51 T 12-10-2018 IPR014790 MutL, C-terminal, dimerisation GO:0005524|GO:0006298 VAPA_1c35740 8d50fad2fd5654c4348155df544b56b8 629 Pfam PF08676 MutL C terminal dimerisation domain 438 585 9.8E-47 T 12-10-2018 IPR014790 MutL, C-terminal, dimerisation GO:0005524|GO:0006298 VAPA_1c35740 8d50fad2fd5654c4348155df544b56b8 629 SMART SM01340 218 336 1.6E-52 T 12-10-2018 IPR013507 DNA mismatch repair protein, S5 domain 2-like GO:0005524|GO:0006298|GO:0030983 VAPA_1c35740 8d50fad2fd5654c4348155df544b56b8 629 SUPERFAMILY SSF55874 14 218 8.51E-51 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_1c35740 8d50fad2fd5654c4348155df544b56b8 629 Hamap MF_00149 DNA mismatch repair protein MutL [mutL]. 14 625 26.781 T 12-10-2018 IPR020667 DNA mismatch repair protein, MutL GO:0006298 VAPA_1c35740 8d50fad2fd5654c4348155df544b56b8 629 Gene3D G3DSA:2.30.42.20 444 622 3.5E-58 T 12-10-2018 VAPA_1c35740 8d50fad2fd5654c4348155df544b56b8 629 Gene3D G3DSA:3.30.1370.100 485 580 3.5E-58 T 12-10-2018 VAPA_2c02150 2e804b1e5d53166f470f21c050a41d13 1610 Gene3D G3DSA:2.180.10.10 991 1179 3.8E-6 T 12-10-2018 VAPA_2c02150 2e804b1e5d53166f470f21c050a41d13 1610 Gene3D G3DSA:2.180.10.10 1180 1501 6.0E-42 T 12-10-2018 VAPA_2c02150 2e804b1e5d53166f470f21c050a41d13 1610 Gene3D G3DSA:3.90.930.1 744 852 5.3E-8 T 12-10-2018 VAPA_2c02150 2e804b1e5d53166f470f21c050a41d13 1610 Gene3D G3DSA:3.90.930.1 595 741 2.5E-7 T 12-10-2018 VAPA_2c02150 2e804b1e5d53166f470f21c050a41d13 1610 Gene3D G3DSA:3.90.930.1 853 944 1.8E-5 T 12-10-2018 VAPA_2c02150 2e804b1e5d53166f470f21c050a41d13 1610 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 875 915 7.5E-8 T 12-10-2018 IPR006530 YD repeat VAPA_2c02150 2e804b1e5d53166f470f21c050a41d13 1610 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 693 733 1.9E-6 T 12-10-2018 IPR006530 YD repeat VAPA_2c02150 2e804b1e5d53166f470f21c050a41d13 1610 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 800 837 4.3E-8 T 12-10-2018 IPR006530 YD repeat VAPA_2c02150 2e804b1e5d53166f470f21c050a41d13 1610 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 758 794 2.0E-6 T 12-10-2018 IPR006530 YD repeat VAPA_2c02150 2e804b1e5d53166f470f21c050a41d13 1610 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 713 752 2.8E-5 T 12-10-2018 IPR006530 YD repeat VAPA_2c02150 2e804b1e5d53166f470f21c050a41d13 1610 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1245 1275 1.7E-4 T 12-10-2018 IPR006530 YD repeat VAPA_2c02150 2e804b1e5d53166f470f21c050a41d13 1610 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 917 957 9.1E-6 T 12-10-2018 IPR006530 YD repeat VAPA_2c02150 2e804b1e5d53166f470f21c050a41d13 1610 Pfam PF03527 RHS protein 1393 1428 4.5E-17 T 12-10-2018 IPR001826 RHS protein VAPA_2c02150 2e804b1e5d53166f470f21c050a41d13 1610 SUPERFAMILY SSF69304 779 985 2.22E-6 T 12-10-2018 VAPA_2c02150 2e804b1e5d53166f470f21c050a41d13 1610 TIGRFAM TIGR03696 Rhs_assc_core: RHS repeat-associated core domain 1420 1501 3.1E-28 T 12-10-2018 IPR022385 Rhs repeat-associated core GO:0097264 VAPA_2c02150 2e804b1e5d53166f470f21c050a41d13 1610 Pfam PF05593 RHS Repeat 693 728 9.6E-6 T 12-10-2018 IPR031325 RHS repeat VAPA_2c02150 2e804b1e5d53166f470f21c050a41d13 1610 Pfam PF05593 RHS Repeat 797 832 9.3E-8 T 12-10-2018 IPR031325 RHS repeat VAPA_2c02150 2e804b1e5d53166f470f21c050a41d13 1610 Pfam PF05593 RHS Repeat 757 791 1.4E-5 T 12-10-2018 IPR031325 RHS repeat VAPA_1c17900 4bd6f662f304b612220004c617a6f55e 307 SUPERFAMILY SSF53474 8 298 3.45E-53 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c17900 4bd6f662f304b612220004c617a6f55e 307 Gene3D G3DSA:3.40.50.1820 1 297 3.9E-76 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c17900 4bd6f662f304b612220004c617a6f55e 307 PRINTS PR00412 Epoxide hydrolase signature 116 129 3.7E-12 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 VAPA_1c17900 4bd6f662f304b612220004c617a6f55e 307 PRINTS PR00412 Epoxide hydrolase signature 54 69 3.7E-12 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 VAPA_1c17900 4bd6f662f304b612220004c617a6f55e 307 PRINTS PR00412 Epoxide hydrolase signature 102 115 3.7E-12 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 VAPA_1c17900 4bd6f662f304b612220004c617a6f55e 307 PRINTS PR00412 Epoxide hydrolase signature 275 297 3.7E-12 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 VAPA_1c17900 4bd6f662f304b612220004c617a6f55e 307 PRINTS PR00412 Epoxide hydrolase signature 34 52 3.7E-12 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 VAPA_1c17900 4bd6f662f304b612220004c617a6f55e 307 Pfam PF00561 alpha/beta hydrolase fold 28 173 3.7E-18 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 VAPA_2c03740 69991985f34fed4459a6c81eae20c07a 230 SMART SM00895 95 219 2.8E-17 T 12-10-2018 IPR011711 GntR, C-terminal VAPA_2c03740 69991985f34fed4459a6c81eae20c07a 230 Pfam PF00392 Bacterial regulatory proteins, gntR family 24 85 6.8E-14 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_2c03740 69991985f34fed4459a6c81eae20c07a 230 SUPERFAMILY SSF46785 20 89 6.19E-13 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_2c03740 69991985f34fed4459a6c81eae20c07a 230 SUPERFAMILY SSF48008 91 227 3.14E-24 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal VAPA_2c03740 69991985f34fed4459a6c81eae20c07a 230 Gene3D G3DSA:1.20.120.530 90 225 7.8E-28 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal VAPA_2c03740 69991985f34fed4459a6c81eae20c07a 230 Pfam PF07729 FCD domain 95 218 1.4E-22 T 12-10-2018 IPR011711 GntR, C-terminal VAPA_2c03740 69991985f34fed4459a6c81eae20c07a 230 SMART SM00345 27 85 2.5E-7 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_2c03740 69991985f34fed4459a6c81eae20c07a 230 Gene3D G3DSA:1.10.10.10 21 86 6.3E-14 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_2c00180 18dbf2e028f54767b0ed008718c3a3e5 325 Gene3D G3DSA:3.40.190.10 127 250 2.0E-117 T 12-10-2018 VAPA_2c00180 18dbf2e028f54767b0ed008718c3a3e5 325 PIRSF PIRSF017082 1 325 8.3E-80 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_2c00180 18dbf2e028f54767b0ed008718c3a3e5 325 SUPERFAMILY SSF53850 99 288 2.61E-13 T 12-10-2018 VAPA_2c00180 18dbf2e028f54767b0ed008718c3a3e5 325 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 48 320 9.7E-91 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_2c00180 18dbf2e028f54767b0ed008718c3a3e5 325 Gene3D G3DSA:3.40.190.150 29 315 2.0E-117 T 12-10-2018 VAPA_1c11760 605f5a31b59f31980a162c06e375141d 534 SUPERFAMILY SSF56024 323 512 1.3E-25 T 12-10-2018 VAPA_1c11760 605f5a31b59f31980a162c06e375141d 534 SMART SM00155 424 451 1.0E-4 T 12-10-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 VAPA_1c11760 605f5a31b59f31980a162c06e375141d 534 SMART SM00155 180 207 0.28 T 12-10-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 VAPA_1c11760 605f5a31b59f31980a162c06e375141d 534 Gene3D G3DSA:3.30.870.10 66 271 1.4E-37 T 12-10-2018 VAPA_1c11760 605f5a31b59f31980a162c06e375141d 534 Pfam PF13091 PLD-like domain 87 239 9.4E-16 T 12-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 VAPA_1c11760 605f5a31b59f31980a162c06e375141d 534 Pfam PF13091 PLD-like domain 338 471 2.8E-18 T 12-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 VAPA_1c11760 605f5a31b59f31980a162c06e375141d 534 Gene3D G3DSA:3.30.870.10 299 486 9.1E-31 T 12-10-2018 VAPA_1c11760 605f5a31b59f31980a162c06e375141d 534 SUPERFAMILY SSF56024 51 248 8.37E-37 T 12-10-2018 VAPA_1c16150 936fddb6bed04998c79c2a9667bd5305 496 Pfam PF00263 Bacterial type II and III secretion system protein 287 454 1.4E-41 T 12-10-2018 IPR004846 Type II/III secretion system GO:0009306 VAPA_1c16150 936fddb6bed04998c79c2a9667bd5305 496 PRINTS PR00811 Bacterial general secretion pathway protein D signature 418 436 1.7E-11 T 12-10-2018 IPR001775 GspD/PilQ family VAPA_1c16150 936fddb6bed04998c79c2a9667bd5305 496 PRINTS PR00811 Bacterial general secretion pathway protein D signature 441 455 1.7E-11 T 12-10-2018 IPR001775 GspD/PilQ family VAPA_1c16150 936fddb6bed04998c79c2a9667bd5305 496 PRINTS PR00811 Bacterial general secretion pathway protein D signature 280 304 1.7E-11 T 12-10-2018 IPR001775 GspD/PilQ family VAPA_1c16150 936fddb6bed04998c79c2a9667bd5305 496 PRINTS PR00811 Bacterial general secretion pathway protein D signature 221 231 1.7E-11 T 12-10-2018 IPR001775 GspD/PilQ family VAPA_1c08540 eeed44bc714c7938ab368bee52c13422 290 Pfam PF02653 Branched-chain amino acid transport system / permease component 11 278 1.4E-36 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 VAPA_1c50150 b6733e49657b5be47ca2f51b0726f3ae 334 Pfam PF14226 non-haem dioxygenase in morphine synthesis N-terminal 7 137 5.0E-31 T 12-10-2018 IPR026992 Non-haem dioxygenase N-terminal domain VAPA_1c50150 b6733e49657b5be47ca2f51b0726f3ae 334 Gene3D G3DSA:2.60.120.330 2 327 1.4E-106 T 12-10-2018 IPR027443 Isopenicillin N synthase-like VAPA_1c50150 b6733e49657b5be47ca2f51b0726f3ae 334 PRINTS PR00682 Isopenicillin N synthase signature 158 174 2.2E-9 T 12-10-2018 VAPA_1c50150 b6733e49657b5be47ca2f51b0726f3ae 334 PRINTS PR00682 Isopenicillin N synthase signature 30 47 2.2E-9 T 12-10-2018 VAPA_1c50150 b6733e49657b5be47ca2f51b0726f3ae 334 PRINTS PR00682 Isopenicillin N synthase signature 275 293 2.2E-9 T 12-10-2018 VAPA_1c50150 b6733e49657b5be47ca2f51b0726f3ae 334 Pfam PF03171 2OG-Fe(II) oxygenase superfamily 184 287 8.0E-16 T 12-10-2018 IPR005123 Oxoglutarate/iron-dependent dioxygenase GO:0016491|GO:0055114 VAPA_1c50150 b6733e49657b5be47ca2f51b0726f3ae 334 SUPERFAMILY SSF51197 4 323 6.59E-87 T 12-10-2018 VAPA_1c00920 86d8d8998150bd31584360c5514fddc7 516 Gene3D G3DSA:3.40.605.10 11 488 3.7E-152 T 12-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 VAPA_1c00920 86d8d8998150bd31584360c5514fddc7 516 Pfam PF00171 Aldehyde dehydrogenase family 21 498 1.8E-59 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 VAPA_1c00920 86d8d8998150bd31584360c5514fddc7 516 SUPERFAMILY SSF53720 3 503 6.94E-74 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 VAPA_1c00920 86d8d8998150bd31584360c5514fddc7 516 Gene3D G3DSA:3.40.309.10 260 476 3.7E-152 T 12-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 VAPA_1c25060 e774a5ec2a39679bb6de7f806380e2a7 188 Pfam PF08281 Sigma-70, region 4 126 174 8.0E-17 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 VAPA_1c25060 e774a5ec2a39679bb6de7f806380e2a7 188 Gene3D G3DSA:1.10.1740.10 2 78 1.4E-5 T 12-10-2018 VAPA_1c25060 e774a5ec2a39679bb6de7f806380e2a7 188 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 7 181 1.7E-19 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 VAPA_1c25060 e774a5ec2a39679bb6de7f806380e2a7 188 SUPERFAMILY SSF88946 9 85 3.02E-7 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 VAPA_1c25060 e774a5ec2a39679bb6de7f806380e2a7 188 SUPERFAMILY SSF88659 120 181 1.29E-15 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like VAPA_1c25060 e774a5ec2a39679bb6de7f806380e2a7 188 Gene3D G3DSA:1.10.10.10 104 185 1.3E-19 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c30030 c276d5f9181b3514794394245423fc23 192 PIRSF PIRSF006135 5 190 7.5E-42 T 12-10-2018 IPR003203 Cobinamide kinase/cobinamide phosphate guanyltransferase GO:0000166|GO:0009236|GO:0043752|GO:0051188 KEGG: 00860+2.7.7.62+2.7.1.156|MetaCyc: PWY-6269|MetaCyc: PWY-7962|MetaCyc: PWY-7971|MetaCyc: PWY-7972 VAPA_1c30030 c276d5f9181b3514794394245423fc23 192 Gene3D G3DSA:3.40.50.300 6 188 1.2E-47 T 12-10-2018 VAPA_1c30030 c276d5f9181b3514794394245423fc23 192 Pfam PF02283 Cobinamide kinase / cobinamide phosphate guanyltransferase 7 187 6.8E-46 T 12-10-2018 IPR003203 Cobinamide kinase/cobinamide phosphate guanyltransferase GO:0000166|GO:0009236|GO:0043752|GO:0051188 KEGG: 00860+2.7.7.62+2.7.1.156|MetaCyc: PWY-6269|MetaCyc: PWY-7962|MetaCyc: PWY-7971|MetaCyc: PWY-7972 VAPA_1c30030 c276d5f9181b3514794394245423fc23 192 SUPERFAMILY SSF52540 7 188 5.2E-41 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c14780 2e880cbef8338a02ce432a2e9fe00311 193 Gene3D G3DSA:3.90.950.10 4 193 9.9E-59 T 12-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like VAPA_1c14780 2e880cbef8338a02ce432a2e9fe00311 193 SUPERFAMILY SSF52972 2 186 3.6E-57 T 12-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like VAPA_1c14780 2e880cbef8338a02ce432a2e9fe00311 193 Hamap MF_00528 Septum formation protein Maf [maf]. 4 192 28.888 T 12-10-2018 IPR003697 Maf-like protein GO:0047429 VAPA_1c14780 2e880cbef8338a02ce432a2e9fe00311 193 PIRSF PIRSF006305 1 193 3.8E-42 T 12-10-2018 IPR003697 Maf-like protein GO:0047429 VAPA_1c14780 2e880cbef8338a02ce432a2e9fe00311 193 Pfam PF02545 Maf-like protein 5 187 1.0E-44 T 12-10-2018 IPR003697 Maf-like protein GO:0047429 VAPA_1c14780 2e880cbef8338a02ce432a2e9fe00311 193 TIGRFAM TIGR00172 maf: septum formation protein Maf 1 186 4.3E-47 T 12-10-2018 IPR003697 Maf-like protein GO:0047429 VAPA_1c02920 d44f030d9b1f49ef4810589fda2a1f3b 576 Hamap MF_00012 Dihydroxy-acid dehydratase [ilvD]. 10 565 40.299 T 12-10-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 VAPA_1c02920 d44f030d9b1f49ef4810589fda2a1f3b 576 SUPERFAMILY SSF143975 5 384 5.23E-116 T 12-10-2018 IPR037237 IlvD/EDD, N-terminal domain KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 VAPA_1c02920 d44f030d9b1f49ef4810589fda2a1f3b 576 Pfam PF00920 Dehydratase family 40 562 6.8E-182 T 12-10-2018 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 VAPA_1c02920 d44f030d9b1f49ef4810589fda2a1f3b 576 Gene3D G3DSA:3.50.30.80 385 536 8.8E-48 T 12-10-2018 VAPA_1c02920 d44f030d9b1f49ef4810589fda2a1f3b 576 SUPERFAMILY SSF52016 385 565 1.88E-49 T 12-10-2018 VAPA_1c02920 d44f030d9b1f49ef4810589fda2a1f3b 576 ProSitePatterns PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2. 471 482 - T 12-10-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 VAPA_1c02920 d44f030d9b1f49ef4810589fda2a1f3b 576 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 128 138 - T 12-10-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 VAPA_1c22000 cfa8bbb2ccfc5ee96024910aee2eebb4 357 Pfam PF00107 Zinc-binding dehydrogenase 183 307 4.8E-25 T 12-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 VAPA_1c22000 cfa8bbb2ccfc5ee96024910aee2eebb4 357 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 143 5.3E-29 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 VAPA_1c22000 cfa8bbb2ccfc5ee96024910aee2eebb4 357 SUPERFAMILY SSF50129 6 182 4.26E-48 T 12-10-2018 IPR011032 GroES-like superfamily VAPA_1c22000 cfa8bbb2ccfc5ee96024910aee2eebb4 357 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 65 79 - T 12-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 VAPA_1c22000 cfa8bbb2ccfc5ee96024910aee2eebb4 357 SUPERFAMILY SSF51735 147 313 5.13E-36 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c22000 cfa8bbb2ccfc5ee96024910aee2eebb4 357 Gene3D G3DSA:3.40.50.720 160 294 1.5E-103 T 12-10-2018 VAPA_1c22000 cfa8bbb2ccfc5ee96024910aee2eebb4 357 SMART SM00829 11 345 3.9E-6 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 VAPA_1c22000 cfa8bbb2ccfc5ee96024910aee2eebb4 357 Gene3D G3DSA:3.90.180.10 13 334 1.5E-103 T 12-10-2018 VAPA_1c06320 8cbf4813c714d129a279fe1a37130240 443 Gene3D G3DSA:3.50.50.60 7 259 6.5E-50 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c06320 8cbf4813c714d129a279fe1a37130240 443 Gene3D G3DSA:3.50.50.60 291 427 7.8E-12 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c06320 8cbf4813c714d129a279fe1a37130240 443 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 136 145 1.3E-5 T 12-10-2018 VAPA_1c06320 8cbf4813c714d129a279fe1a37130240 443 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 12 34 1.3E-5 T 12-10-2018 VAPA_1c06320 8cbf4813c714d129a279fe1a37130240 443 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 177 202 1.3E-5 T 12-10-2018 VAPA_1c06320 8cbf4813c714d129a279fe1a37130240 443 TIGRFAM TIGR04046 MSMEG_0569_nitr: flavin-dependent oxidoreductase, MSMEG_0569 family 11 415 1.6E-201 T 12-10-2018 IPR024000 Conserved hypothetical protein CHP04046, FMN-dependent VAPA_1c06320 8cbf4813c714d129a279fe1a37130240 443 SUPERFAMILY SSF51905 178 389 1.4E-5 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c06320 8cbf4813c714d129a279fe1a37130240 443 Pfam PF13738 Pyridine nucleotide-disulphide oxidoreductase 14 209 1.1E-20 T 12-10-2018 VAPA_1c06320 8cbf4813c714d129a279fe1a37130240 443 SUPERFAMILY SSF51905 9 259 2.07E-32 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c53840 5128396f46d42ad65e9ae781345839ab 451 Pfam PF13579 Glycosyl transferase 4-like domain 134 225 4.2E-10 T 12-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 VAPA_1c53840 5128396f46d42ad65e9ae781345839ab 451 SUPERFAMILY SSF53756 8 418 4.29E-25 T 12-10-2018 VAPA_1c53840 5128396f46d42ad65e9ae781345839ab 451 Gene3D G3DSA:3.40.50.2000 248 426 1.6E-11 T 12-10-2018 VAPA_1c53070 acc719f039be89398d9ba0ce8107d527 172 Pfam PF04361 Protein of unknown function (DUF494) 1 172 3.0E-52 T 12-10-2018 IPR007456 Smg VAPA_1c53070 acc719f039be89398d9ba0ce8107d527 172 Hamap MF_00598 Protein Smg [smg]. 1 172 23.718 T 12-10-2018 IPR007456 Smg VAPA_2c04410 18a4bca9adac889556a016675835b49d 155 Pfam PF02082 Transcriptional regulator 1 81 4.7E-25 T 12-10-2018 IPR000944 Transcription regulator Rrf2-type VAPA_2c04410 18a4bca9adac889556a016675835b49d 155 Gene3D G3DSA:1.10.10.10 1 140 2.9E-33 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_2c04410 18a4bca9adac889556a016675835b49d 155 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 1 130 1.9E-31 T 12-10-2018 IPR000944 Transcription regulator Rrf2-type VAPA_2c04410 18a4bca9adac889556a016675835b49d 155 SUPERFAMILY SSF46785 2 133 6.82E-35 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c07410 0d32896ab42d1e9bff4608c5a180c296 125 Pfam PF00542 Ribosomal protein L7/L12 C-terminal domain 59 125 1.6E-30 T 12-10-2018 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 VAPA_1c07410 0d32896ab42d1e9bff4608c5a180c296 125 Hamap MF_00368 50S ribosomal protein L7/L12 [rplL]. 2 125 25.176 T 12-10-2018 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 VAPA_1c07410 0d32896ab42d1e9bff4608c5a180c296 125 Gene3D G3DSA:3.30.1390.10 55 125 1.6E-30 T 12-10-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like VAPA_1c07410 0d32896ab42d1e9bff4608c5a180c296 125 SUPERFAMILY SSF48300 4 61 3.4E-15 T 12-10-2018 IPR036235 Ribosomal protein L7/L12, oligomerisation domain superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 VAPA_1c07410 0d32896ab42d1e9bff4608c5a180c296 125 ProDom PD001326 RIBOSOMAL L7/L12 50S RIBONUCLEOPROTEIN CHLOROPLAST L12 PLASTID DIRECT SEQUENCING PEPTIDE 61 104 5.0E-12 T 12-10-2018 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 VAPA_1c07410 0d32896ab42d1e9bff4608c5a180c296 125 Pfam PF16320 Ribosomal protein L7/L12 dimerisation domain 5 51 1.5E-17 T 12-10-2018 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 VAPA_1c07410 0d32896ab42d1e9bff4608c5a180c296 125 TIGRFAM TIGR00855 L12: ribosomal protein bL12 1 125 1.2E-46 T 12-10-2018 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 VAPA_1c07410 0d32896ab42d1e9bff4608c5a180c296 125 SUPERFAMILY SSF54736 54 125 9.42E-25 T 12-10-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like VAPA_1c07410 0d32896ab42d1e9bff4608c5a180c296 125 Gene3D G3DSA:1.20.5.710 4 54 3.8E-18 T 12-10-2018 VAPA_1c43810 79e4a71e1cf1ae6b4701e33d5c7ce13e 201 SUPERFAMILY SSF52540 1 194 6.95E-37 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c43810 79e4a71e1cf1ae6b4701e33d5c7ce13e 201 Pfam PF01121 Dephospho-CoA kinase 4 178 1.2E-51 T 12-10-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 VAPA_1c43810 79e4a71e1cf1ae6b4701e33d5c7ce13e 201 TIGRFAM TIGR00152 TIGR00152: dephospho-CoA kinase 4 187 2.6E-42 T 12-10-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 VAPA_1c43810 79e4a71e1cf1ae6b4701e33d5c7ce13e 201 Gene3D G3DSA:3.40.50.300 1 197 1.3E-61 T 12-10-2018 VAPA_1c43810 79e4a71e1cf1ae6b4701e33d5c7ce13e 201 Hamap MF_00376 Dephospho-CoA kinase [coaE]. 1 194 26.441 T 12-10-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 VAPA_1c43360 f5d6ab562712dd4721ea11b446da0bdc 89 PIRSF PIRSF004669 1 89 5.6E-35 T 12-10-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 VAPA_1c43360 f5d6ab562712dd4721ea11b446da0bdc 89 Pfam PF01313 Bacterial export proteins, family 3 6 77 2.5E-32 T 12-10-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 VAPA_1c43360 f5d6ab562712dd4721ea11b446da0bdc 89 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 18 39 3.6E-25 T 12-10-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 VAPA_1c43360 f5d6ab562712dd4721ea11b446da0bdc 89 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 54 76 3.6E-25 T 12-10-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 VAPA_1c43360 f5d6ab562712dd4721ea11b446da0bdc 89 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 39 54 3.6E-25 T 12-10-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 VAPA_1c43360 f5d6ab562712dd4721ea11b446da0bdc 89 TIGRFAM TIGR01402 fliQ: flagellar biosynthetic protein FliQ 1 87 6.4E-35 T 12-10-2018 IPR006305 Flagellar biosynthesis protein FliQ GO:0016021|GO:0044780 VAPA_1c08470 cdb56ad034a0fa8e19e86463df8c907b 331 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 36 309 2.6E-71 T 12-10-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0030288|GO:0055085 VAPA_1c08470 cdb56ad034a0fa8e19e86463df8c907b 331 Gene3D G3DSA:3.40.190.170 30 329 3.1E-86 T 12-10-2018 IPR038404 TRAP transporter solute receptor DctP superfamily VAPA_1c08470 cdb56ad034a0fa8e19e86463df8c907b 331 PIRSF PIRSF006470 1 329 4.0E-72 T 12-10-2018 IPR004682 TRAP transporter solute receptor, DctP family GO:0030288|GO:0055085 VAPA_1c08470 cdb56ad034a0fa8e19e86463df8c907b 331 TIGRFAM TIGR00787 dctP: TRAP transporter solute receptor, DctP family 36 292 4.7E-64 T 12-10-2018 IPR004682 TRAP transporter solute receptor, DctP family GO:0030288|GO:0055085 VAPA_1c08470 cdb56ad034a0fa8e19e86463df8c907b 331 SUPERFAMILY SSF53850 48 220 6.73E-5 T 12-10-2018 VAPA_1c43690 6c316ff2ac7b28830d0d0eaf06e025f7 581 SUPERFAMILY SSF55826 218 398 1.29E-29 T 12-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 VAPA_1c43690 6c316ff2ac7b28830d0d0eaf06e025f7 581 TIGRFAM TIGR00409 proS_fam_II: proline--tRNA ligase 1 575 2.9E-214 T 12-10-2018 IPR004500 Prolyl-tRNA synthetase, class IIa, bacterial-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 VAPA_1c43690 6c316ff2ac7b28830d0d0eaf06e025f7 581 Gene3D G3DSA:3.30.930.10 11 474 5.6E-227 T 12-10-2018 VAPA_1c43690 6c316ff2ac7b28830d0d0eaf06e025f7 581 PIRSF PIRSF001535 1 581 1.1E-257 T 12-10-2018 IPR023717 Prolyl-tRNA synthetase, class IIa, type 1 GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 VAPA_1c43690 6c316ff2ac7b28830d0d0eaf06e025f7 581 Pfam PF03129 Anticodon binding domain 485 575 5.6E-16 T 12-10-2018 IPR004154 Anticodon-binding VAPA_1c43690 6c316ff2ac7b28830d0d0eaf06e025f7 581 Gene3D G3DSA:3.40.50.800 4 562 5.6E-227 T 12-10-2018 IPR036621 Anticodon-binding domain superfamily VAPA_1c43690 6c316ff2ac7b28830d0d0eaf06e025f7 581 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 95 468 2.5E-43 T 12-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 VAPA_1c43690 6c316ff2ac7b28830d0d0eaf06e025f7 581 Pfam PF04073 Aminoacyl-tRNA editing domain 257 387 1.8E-26 T 12-10-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 VAPA_1c43690 6c316ff2ac7b28830d0d0eaf06e025f7 581 Gene3D G3DSA:3.90.960.10 240 398 5.6E-227 T 12-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 VAPA_1c43690 6c316ff2ac7b28830d0d0eaf06e025f7 581 Hamap MF_01569 Proline--tRNA ligase [proS]. 1 580 39.858 T 12-10-2018 IPR023717 Prolyl-tRNA synthetase, class IIa, type 1 GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 VAPA_1c43690 6c316ff2ac7b28830d0d0eaf06e025f7 581 PRINTS PR01046 Prolyl-tRNA synthetase signature 68 86 1.1E-16 T 12-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 VAPA_1c43690 6c316ff2ac7b28830d0d0eaf06e025f7 581 PRINTS PR01046 Prolyl-tRNA synthetase signature 134 142 1.1E-16 T 12-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 VAPA_1c43690 6c316ff2ac7b28830d0d0eaf06e025f7 581 PRINTS PR01046 Prolyl-tRNA synthetase signature 104 115 1.1E-16 T 12-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 VAPA_1c43690 6c316ff2ac7b28830d0d0eaf06e025f7 581 PRINTS PR01046 Prolyl-tRNA synthetase signature 144 155 1.1E-16 T 12-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 VAPA_1c43690 6c316ff2ac7b28830d0d0eaf06e025f7 581 SUPERFAMILY SSF55681 10 487 1.65E-97 T 12-10-2018 VAPA_1c43690 6c316ff2ac7b28830d0d0eaf06e025f7 581 SUPERFAMILY SSF52954 473 579 9.32E-28 T 12-10-2018 VAPA_1c29980 b5b27b09abd66c8186dbed4e41e053eb 314 Hamap MF_00024 Cobalamin biosynthesis protein CbiB [cbiB]. 1 314 83.451 T 12-10-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 VAPA_1c29980 b5b27b09abd66c8186dbed4e41e053eb 314 TIGRFAM TIGR00380 cobD: cobalamin biosynthesis protein CobD 5 289 1.3E-61 T 12-10-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 VAPA_1c29980 b5b27b09abd66c8186dbed4e41e053eb 314 Pfam PF03186 CobD/Cbib protein 8 287 6.1E-81 T 12-10-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 VAPA_1c39720 45ef1cbc3c36cc38ed4b1f3f3545925f 1044 SUPERFAMILY SSF103515 740 1044 1.44E-40 T 12-10-2018 IPR036709 Autotransporter beta-domain superfamily VAPA_1c39720 45ef1cbc3c36cc38ed4b1f3f3545925f 1044 Pfam PF03797 Autotransporter beta-domain 774 1018 6.4E-44 T 12-10-2018 IPR005546 Autotransporter beta-domain VAPA_1c39720 45ef1cbc3c36cc38ed4b1f3f3545925f 1044 Gene3D G3DSA:2.160.20.20 486 667 2.6E-32 T 12-10-2018 IPR012332 P22 tailspike-like, C-terminal domain superfamily VAPA_1c39720 45ef1cbc3c36cc38ed4b1f3f3545925f 1044 Pfam PF03212 Pertactin 563 664 1.1E-4 T 12-10-2018 IPR004899 Pertactin, central region VAPA_1c39720 45ef1cbc3c36cc38ed4b1f3f3545925f 1044 SUPERFAMILY SSF51126 236 665 8.47E-25 T 12-10-2018 IPR011050 Pectin lyase fold/virulence factor VAPA_1c39720 45ef1cbc3c36cc38ed4b1f3f3545925f 1044 SMART SM00869 770 1029 5.3E-35 T 12-10-2018 IPR005546 Autotransporter beta-domain VAPA_1c39720 45ef1cbc3c36cc38ed4b1f3f3545925f 1044 Pfam PF13018 Extended Signal Peptide of Type V secretion system 1 24 3.0E-8 T 12-10-2018 IPR024973 ESPR domain VAPA_1c39720 45ef1cbc3c36cc38ed4b1f3f3545925f 1044 Gene3D G3DSA:2.40.128.130 723 1044 9.4E-64 T 12-10-2018 IPR036709 Autotransporter beta-domain superfamily VAPA_1c39720 45ef1cbc3c36cc38ed4b1f3f3545925f 1044 TIGRFAM TIGR01414 autotrans_barl: outer membrane autotransporter barrel domain 545 1044 1.1E-66 T 12-10-2018 IPR006315 Outer membrane autotransporter barrel GO:0019867 VAPA_1c16380 b86a0bb68f2535c94637c9484bf7f104 427 Pfam PF07687 Peptidase dimerisation domain 218 316 1.1E-19 T 12-10-2018 IPR011650 Peptidase M20, dimerisation domain VAPA_1c16380 b86a0bb68f2535c94637c9484bf7f104 427 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 113 122 - T 12-10-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 VAPA_1c16380 b86a0bb68f2535c94637c9484bf7f104 427 Pfam PF01546 Peptidase family M20/M25/M40 114 417 3.8E-27 T 12-10-2018 IPR002933 Peptidase M20 GO:0016787 VAPA_1c16380 b86a0bb68f2535c94637c9484bf7f104 427 Gene3D G3DSA:3.40.630.10 43 409 5.0E-114 T 12-10-2018 VAPA_1c16380 b86a0bb68f2535c94637c9484bf7f104 427 SUPERFAMILY SSF55031 221 332 2.22E-22 T 12-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain VAPA_1c16380 b86a0bb68f2535c94637c9484bf7f104 427 Gene3D G3DSA:3.30.70.360 220 329 5.0E-114 T 12-10-2018 VAPA_1c16380 b86a0bb68f2535c94637c9484bf7f104 427 PIRSF PIRSF037238 26 421 1.2E-103 T 12-10-2018 IPR017150 Peptidase M20, glutamate carboxypeptidase VAPA_1c16380 b86a0bb68f2535c94637c9484bf7f104 427 SUPERFAMILY SSF53187 29 420 7.71E-49 T 12-10-2018 VAPA_1c19130 58cb2bb51dd56d6071f73dd7127a528e 158 SUPERFAMILY SSF52833 3 154 1.94E-46 T 12-10-2018 IPR036249 Thioredoxin-like superfamily VAPA_1c19130 58cb2bb51dd56d6071f73dd7127a528e 158 Pfam PF00578 AhpC/TSA family 5 133 6.5E-31 T 12-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 VAPA_1c19130 58cb2bb51dd56d6071f73dd7127a528e 158 PIRSF PIRSF000239 1 158 3.3E-29 T 12-10-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 VAPA_1c19130 58cb2bb51dd56d6071f73dd7127a528e 158 Gene3D G3DSA:3.40.30.10 2 156 1.9E-42 T 12-10-2018 VAPA_1c33720 db3c2e738d49bf53be13379ea34b2ce8 188 SMART SM00091 4 70 1.1E-5 T 12-10-2018 IPR000014 PAS domain VAPA_1c33720 db3c2e738d49bf53be13379ea34b2ce8 188 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 6 126 2.8E-9 T 12-10-2018 IPR000014 PAS domain VAPA_1c33720 db3c2e738d49bf53be13379ea34b2ce8 188 Pfam PF00196 Bacterial regulatory proteins, luxR family 130 183 4.0E-15 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_1c33720 db3c2e738d49bf53be13379ea34b2ce8 188 ProSitePatterns PS00622 LuxR-type HTH domain signature. 145 172 - T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_1c33720 db3c2e738d49bf53be13379ea34b2ce8 188 SUPERFAMILY SSF46894 117 185 1.46E-17 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 VAPA_1c33720 db3c2e738d49bf53be13379ea34b2ce8 188 Gene3D G3DSA:1.10.10.10 126 187 1.6E-18 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c33720 db3c2e738d49bf53be13379ea34b2ce8 188 Gene3D G3DSA:3.30.450.20 2 125 1.8E-21 T 12-10-2018 VAPA_1c33720 db3c2e738d49bf53be13379ea34b2ce8 188 SUPERFAMILY SSF55785 5 120 7.5E-10 T 12-10-2018 IPR035965 PAS domain superfamily VAPA_1c33720 db3c2e738d49bf53be13379ea34b2ce8 188 Pfam PF13426 PAS domain 14 120 2.3E-7 T 12-10-2018 IPR000014 PAS domain VAPA_1c33720 db3c2e738d49bf53be13379ea34b2ce8 188 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 131 145 2.5E-11 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_1c33720 db3c2e738d49bf53be13379ea34b2ce8 188 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 145 161 2.5E-11 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_1c33720 db3c2e738d49bf53be13379ea34b2ce8 188 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 161 173 2.5E-11 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_1c33720 db3c2e738d49bf53be13379ea34b2ce8 188 SMART SM00421 128 185 1.2E-17 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_2c10330 bc5a43f9eeab72dda1ab4349e0b6f673 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 7.1E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_2c10330 bc5a43f9eeab72dda1ab4349e0b6f673 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 7.1E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_2c10330 bc5a43f9eeab72dda1ab4349e0b6f673 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 7.1E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_2c10330 bc5a43f9eeab72dda1ab4349e0b6f673 297 Pfam PF03466 LysR substrate binding domain 87 288 6.5E-36 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_2c10330 bc5a43f9eeab72dda1ab4349e0b6f673 297 Gene3D G3DSA:3.40.190.290 91 290 3.4E-38 T 12-10-2018 VAPA_2c10330 bc5a43f9eeab72dda1ab4349e0b6f673 297 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 4.1E-21 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_2c10330 bc5a43f9eeab72dda1ab4349e0b6f673 297 SUPERFAMILY SSF46785 1 87 1.41E-22 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_2c10330 bc5a43f9eeab72dda1ab4349e0b6f673 297 SUPERFAMILY SSF53850 89 289 7.14E-32 T 12-10-2018 VAPA_2c10330 bc5a43f9eeab72dda1ab4349e0b6f673 297 Gene3D G3DSA:1.10.10.10 1 88 1.2E-27 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c27320 ef33d6a231395e3df8f764b6e23bf7a8 303 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 131 206 8.6E-14 T 12-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 VAPA_1c27320 ef33d6a231395e3df8f764b6e23bf7a8 303 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 228 293 5.6E-10 T 12-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 VAPA_1c27320 ef33d6a231395e3df8f764b6e23bf7a8 303 Gene3D G3DSA:1.10.760.10 186 273 3.3E-67 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 VAPA_1c27320 ef33d6a231395e3df8f764b6e23bf7a8 303 Gene3D G3DSA:1.10.760.10 108 295 3.3E-67 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 VAPA_1c27320 ef33d6a231395e3df8f764b6e23bf7a8 303 PRINTS PR00605 Class IC cytochrome C signature 141 152 4.0E-6 T 12-10-2018 IPR008168 Cytochrome c, class IC GO:0005506|GO:0009055 VAPA_1c27320 ef33d6a231395e3df8f764b6e23bf7a8 303 PRINTS PR00605 Class IC cytochrome C signature 271 293 4.0E-6 T 12-10-2018 IPR008168 Cytochrome c, class IC GO:0005506|GO:0009055 VAPA_1c27320 ef33d6a231395e3df8f764b6e23bf7a8 303 PIRSF PIRSF000006 5 300 1.3E-89 T 12-10-2018 IPR004678 Cytochrome c oxidase cbb3-type, subunit III VAPA_1c27320 ef33d6a231395e3df8f764b6e23bf7a8 303 TIGRFAM TIGR00782 ccoP: cytochrome c oxidase, cbb3-type, subunit III 42 297 7.6E-77 T 12-10-2018 IPR004678 Cytochrome c oxidase cbb3-type, subunit III VAPA_1c27320 ef33d6a231395e3df8f764b6e23bf7a8 303 Pfam PF14715 N-terminal domain of cytochrome oxidase-cbb3, FixP 41 87 3.6E-21 T 12-10-2018 IPR032858 Cbb3-type cytochrome c oxidase subunit CcoP, N-terminal VAPA_1c27320 ef33d6a231395e3df8f764b6e23bf7a8 303 Gene3D G3DSA:1.20.58.1490 5 98 1.1E-29 T 12-10-2018 IPR038414 Cbb3-type cytochrome c oxidase subunit CcoP, N-terminal domain superfamily VAPA_1c27320 ef33d6a231395e3df8f764b6e23bf7a8 303 SUPERFAMILY SSF46626 227 299 4.65E-18 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 VAPA_1c27320 ef33d6a231395e3df8f764b6e23bf7a8 303 SUPERFAMILY SSF46626 60 215 2.04E-30 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 VAPA_1c40170 5160f829bcddcafa767cf79280aa8afd 330 SUPERFAMILY SSF53850 120 290 8.03E-8 T 12-10-2018 VAPA_1c40170 5160f829bcddcafa767cf79280aa8afd 330 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 55 326 3.7E-72 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c40170 5160f829bcddcafa767cf79280aa8afd 330 Gene3D G3DSA:3.40.190.10 132 255 1.3E-98 T 12-10-2018 VAPA_1c40170 5160f829bcddcafa767cf79280aa8afd 330 Gene3D G3DSA:3.40.190.150 35 320 1.3E-98 T 12-10-2018 VAPA_1c40170 5160f829bcddcafa767cf79280aa8afd 330 PIRSF PIRSF017082 1 330 3.1E-72 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c18020 44320f0bf4c3f12becd3a34a8bd80435 176 Hamap MF_01151 Protein GrpE [grpE]. 5 174 19.362 T 12-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 VAPA_1c18020 44320f0bf4c3f12becd3a34a8bd80435 176 Gene3D G3DSA:3.90.20.20 4 114 1.0E-22 T 12-10-2018 IPR013805 GrpE nucleotide exchange factor, coiled-coil Reactome: R-HSA-1268020 VAPA_1c18020 44320f0bf4c3f12becd3a34a8bd80435 176 Pfam PF01025 GrpE 14 173 3.9E-51 T 12-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 VAPA_1c18020 44320f0bf4c3f12becd3a34a8bd80435 176 PRINTS PR00773 GrpE protein signature 73 88 1.0E-24 T 12-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 VAPA_1c18020 44320f0bf4c3f12becd3a34a8bd80435 176 PRINTS PR00773 GrpE protein signature 126 141 1.0E-24 T 12-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 VAPA_1c18020 44320f0bf4c3f12becd3a34a8bd80435 176 PRINTS PR00773 GrpE protein signature 45 61 1.0E-24 T 12-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 VAPA_1c18020 44320f0bf4c3f12becd3a34a8bd80435 176 PRINTS PR00773 GrpE protein signature 153 172 1.0E-24 T 12-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 VAPA_1c18020 44320f0bf4c3f12becd3a34a8bd80435 176 ProSitePatterns PS01071 grpE protein signature. 129 172 - T 12-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 VAPA_1c18020 44320f0bf4c3f12becd3a34a8bd80435 176 SUPERFAMILY SSF51064 119 174 1.07E-18 T 12-10-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 VAPA_1c18020 44320f0bf4c3f12becd3a34a8bd80435 176 Gene3D G3DSA:2.30.22.10 115 174 2.9E-23 T 12-10-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 VAPA_1c18020 44320f0bf4c3f12becd3a34a8bd80435 176 SUPERFAMILY SSF58014 24 115 1.23E-22 T 12-10-2018 IPR013805 GrpE nucleotide exchange factor, coiled-coil Reactome: R-HSA-1268020 VAPA_1c48120 7fc6f17f3d4522c51d796ddcab8e1167 333 Gene3D G3DSA:3.40.190.10 133 258 5.3E-98 T 12-10-2018 VAPA_1c48120 7fc6f17f3d4522c51d796ddcab8e1167 333 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 55 307 1.6E-74 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c48120 7fc6f17f3d4522c51d796ddcab8e1167 333 SUPERFAMILY SSF53850 123 296 3.64E-7 T 12-10-2018 VAPA_1c48120 7fc6f17f3d4522c51d796ddcab8e1167 333 PIRSF PIRSF017082 1 318 1.8E-68 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c48120 7fc6f17f3d4522c51d796ddcab8e1167 333 Gene3D G3DSA:3.40.190.150 35 314 5.3E-98 T 12-10-2018 VAPA_1c45440 ef7134fa240dc487451915a8669edfe6 305 TIGRFAM TIGR03298 argP: transcriptional regulator, ArgP family 2 298 3.0E-117 T 12-10-2018 IPR017685 HTH-type transcriptional regulator ArgP VAPA_1c45440 ef7134fa240dc487451915a8669edfe6 305 SUPERFAMILY SSF53850 97 298 1.99E-23 T 12-10-2018 VAPA_1c45440 ef7134fa240dc487451915a8669edfe6 305 SUPERFAMILY SSF46785 1 113 2.72E-16 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c45440 ef7134fa240dc487451915a8669edfe6 305 Gene3D G3DSA:3.40.190.290 94 300 5.2E-77 T 12-10-2018 VAPA_1c45440 ef7134fa240dc487451915a8669edfe6 305 Gene3D G3DSA:1.10.10.10 1 82 1.9E-26 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c45440 ef7134fa240dc487451915a8669edfe6 305 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 62 1.1E-16 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c45440 ef7134fa240dc487451915a8669edfe6 305 Pfam PF03466 LysR substrate binding domain 96 297 1.1E-19 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_1c07670 47cb4a4f9f21658d4554796c65f68cb3 125 Pfam PF00216 Bacterial DNA-binding protein 2 89 4.8E-26 T 12-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 VAPA_1c07670 47cb4a4f9f21658d4554796c65f68cb3 125 SUPERFAMILY SSF47729 2 90 1.27E-25 T 12-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 VAPA_1c07670 47cb4a4f9f21658d4554796c65f68cb3 125 SMART SM00411 1 90 7.3E-33 T 12-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 VAPA_1c07670 47cb4a4f9f21658d4554796c65f68cb3 125 PRINTS PR01727 Prokaryotic integration host factor signature 74 88 1.2E-11 T 12-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 VAPA_1c07670 47cb4a4f9f21658d4554796c65f68cb3 125 PRINTS PR01727 Prokaryotic integration host factor signature 40 55 1.2E-11 T 12-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 VAPA_1c07670 47cb4a4f9f21658d4554796c65f68cb3 125 PRINTS PR01727 Prokaryotic integration host factor signature 58 71 1.2E-11 T 12-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 VAPA_1c07670 47cb4a4f9f21658d4554796c65f68cb3 125 Gene3D G3DSA:4.10.520.10 1 99 1.2E-28 T 12-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 VAPA_2c10310 17422c1e54f42851e54718346d9cfdc7 278 SUPERFAMILY SSF46894 195 266 8.5E-14 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 VAPA_2c10310 17422c1e54f42851e54718346d9cfdc7 278 Gene3D G3DSA:1.10.10.10 170 272 1.7E-12 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_2c10310 17422c1e54f42851e54718346d9cfdc7 278 Pfam PF00196 Bacterial regulatory proteins, luxR family 210 263 5.2E-12 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_2c10310 17422c1e54f42851e54718346d9cfdc7 278 SMART SM00421 208 265 4.4E-11 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_1c14300 53a7a115328cfbac9009787894e63765 73 SUPERFAMILY SSF103647 37 71 8.24E-8 T 12-10-2018 IPR028974 TSP type-3 repeat GO:0005509 Reactome: R-HSA-186797 VAPA_1c42000 b08b383b74b5851f7801ded2f0ad2507 220 Pfam PF03006 Haemolysin-III related 15 211 1.4E-36 T 12-10-2018 IPR004254 AdipoR/Haemolysin-III-related GO:0016021 VAPA_1c42000 b08b383b74b5851f7801ded2f0ad2507 220 TIGRFAM TIGR01065 hlyIII: channel protein, hemolysin III family 17 215 8.5E-56 T 12-10-2018 IPR005744 Hly-III GO:0016021|GO:0019835 VAPA_1c22650 6503d1a172247bec0574b284b2503b3d 245 TIGRFAM TIGR02303 HpaG-C-term: 4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase, C-terminal subunit 2 244 7.7E-113 T 12-10-2018 IPR012684 4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase, C-terminal subunit GO:0008704|GO:0018800|GO:1901023 KEGG: 00350+5.3.3.10+4.1.1.68 VAPA_1c22650 6503d1a172247bec0574b284b2503b3d 245 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 46 242 5.5E-59 T 12-10-2018 IPR011234 Fumarylacetoacetase-like, C-terminal GO:0003824 VAPA_1c22650 6503d1a172247bec0574b284b2503b3d 245 SUPERFAMILY SSF56529 35 244 2.49E-71 T 12-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 VAPA_1c22650 6503d1a172247bec0574b284b2503b3d 245 Gene3D G3DSA:3.90.850.10 38 245 2.0E-73 T 12-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 VAPA_1c36950 e823157c419e15e2d8fc788ca96115ec 438 Gene3D G3DSA:3.30.1120.10 349 427 3.6E-11 T 12-10-2018 VAPA_1c36950 e823157c419e15e2d8fc788ca96115ec 438 Pfam PF00884 Sulfatase 4 326 1.0E-71 T 12-10-2018 IPR000917 Sulfatase, N-terminal GO:0008484 VAPA_1c36950 e823157c419e15e2d8fc788ca96115ec 438 Gene3D G3DSA:3.40.720.10 2 348 2.4E-101 T 12-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 VAPA_1c36950 e823157c419e15e2d8fc788ca96115ec 438 SUPERFAMILY SSF53649 3 415 1.38E-115 T 12-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 VAPA_1c36950 e823157c419e15e2d8fc788ca96115ec 438 ProSitePatterns PS00149 Sulfatases signature 2. 107 117 - T 12-10-2018 IPR024607 Sulfatase, conserved site VAPA_1c29880 e688ad005c8127a98d8cd63ca5cd8ec9 479 TIGRFAM TIGR00313 cobQ: cobyric acid synthase CobQ 6 440 1.2E-121 T 12-10-2018 IPR004459 Cobyric acid synthase CobQ GO:0003824|GO:0009236 VAPA_1c29880 e688ad005c8127a98d8cd63ca5cd8ec9 479 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 252 440 7.2E-46 T 12-10-2018 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 VAPA_1c29880 e688ad005c8127a98d8cd63ca5cd8ec9 479 Hamap MF_00028 Cobyric acid synthase [cobQ]. 1 479 161.92 T 12-10-2018 IPR004459 Cobyric acid synthase CobQ GO:0003824|GO:0009236 VAPA_1c29880 e688ad005c8127a98d8cd63ca5cd8ec9 479 Gene3D G3DSA:3.40.50.300 5 239 2.2E-49 T 12-10-2018 VAPA_1c29880 e688ad005c8127a98d8cd63ca5cd8ec9 479 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 6 224 2.2E-17 T 12-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain VAPA_1c29880 e688ad005c8127a98d8cd63ca5cd8ec9 479 SUPERFAMILY SSF52317 252 434 1.58E-35 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like VAPA_1c29880 e688ad005c8127a98d8cd63ca5cd8ec9 479 Gene3D G3DSA:3.40.50.880 250 434 5.4E-23 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like VAPA_1c29880 e688ad005c8127a98d8cd63ca5cd8ec9 479 SUPERFAMILY SSF52540 1 238 2.5E-48 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c28200 5adbf81f22014dc89b31285a64553c68 766 Gene3D G3DSA:3.90.100.10 642 763 5.5E-36 T 12-10-2018 VAPA_1c28200 5adbf81f22014dc89b31285a64553c68 766 Gene3D G3DSA:3.90.1150.10 459 641 6.4E-64 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 VAPA_1c28200 5adbf81f22014dc89b31285a64553c68 766 Pfam PF03711 Orn/Lys/Arg decarboxylase, C-terminal domain 622 746 1.1E-44 T 12-10-2018 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 VAPA_1c28200 5adbf81f22014dc89b31285a64553c68 766 PIRSF PIRSF009393 1 763 6.1E-272 T 12-10-2018 IPR011193 Ornithine/lysine/arginine decarboxylase GO:0005737|GO:0006520|GO:0016831 VAPA_1c28200 5adbf81f22014dc89b31285a64553c68 766 Pfam PF01276 Orn/Lys/Arg decarboxylase, major domain 149 595 9.2E-145 T 12-10-2018 IPR000310 Orn/Lys/Arg decarboxylase, major domain GO:0003824 VAPA_1c28200 5adbf81f22014dc89b31285a64553c68 766 SUPERFAMILY SSF53383 149 613 2.14E-111 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase VAPA_1c28200 5adbf81f22014dc89b31285a64553c68 766 SUPERFAMILY SSF55904 617 762 5.62E-44 T 12-10-2018 IPR036633 Orn/Lys/Arg decarboxylase, C-terminal domain superfamily GO:0003824 VAPA_1c28200 5adbf81f22014dc89b31285a64553c68 766 Pfam PF03709 Orn/Lys/Arg decarboxylase, N-terminal domain 20 143 1.8E-37 T 12-10-2018 IPR005308 Orn/Lys/Arg decarboxylase, N-terminal GO:0016831 VAPA_1c28200 5adbf81f22014dc89b31285a64553c68 766 Gene3D G3DSA:3.40.50.2300 5 147 6.6E-19 T 12-10-2018 VAPA_1c28200 5adbf81f22014dc89b31285a64553c68 766 Gene3D G3DSA:3.40.640.10 149 456 1.1E-94 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 VAPA_1c28200 5adbf81f22014dc89b31285a64553c68 766 ProSitePatterns PS00703 Orn/Lys/Arg decarboxylases family 1 pyridoxal-P attachment site. 392 406 - T 12-10-2018 IPR000310 Orn/Lys/Arg decarboxylase, major domain GO:0003824 VAPA_1c02800 99e6146558acc436e406432240217126 500 Gene3D G3DSA:3.30.465.40 19 252 3.7E-58 T 12-10-2018 VAPA_1c02800 99e6146558acc436e406432240217126 500 Pfam PF01565 FAD binding domain 57 195 2.3E-36 T 12-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 VAPA_1c02800 99e6146558acc436e406432240217126 500 Gene3D G3DSA:1.10.45.10 433 473 1.1E-6 T 12-10-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 VAPA_1c02800 99e6146558acc436e406432240217126 500 SUPERFAMILY SSF56176 20 232 1.26E-63 T 12-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 VAPA_1c02800 99e6146558acc436e406432240217126 500 Pfam PF02913 FAD linked oxidases, C-terminal domain 231 471 3.5E-63 T 12-10-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 VAPA_1c02800 99e6146558acc436e406432240217126 500 SUPERFAMILY SSF55103 206 475 1.11E-70 T 12-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 VAPA_1c02800 99e6146558acc436e406432240217126 500 Gene3D G3DSA:3.30.70.2740 352 432 1.8E-8 T 12-10-2018 VAPA_2c10150 7e09665ae8e8912060fe023cea3b47d0 650 SMART SM00387 537 648 9.4E-28 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase VAPA_2c10150 7e09665ae8e8912060fe023cea3b47d0 650 Gene3D G3DSA:1.10.287.130 379 481 7.9E-6 T 12-10-2018 VAPA_2c10150 7e09665ae8e8912060fe023cea3b47d0 650 Pfam PF05226 CHASE2 domain 24 318 3.1E-55 T 12-10-2018 IPR007890 CHASE2 VAPA_2c10150 7e09665ae8e8912060fe023cea3b47d0 650 PRINTS PR00344 Bacterial sensor protein C-terminal signature 575 589 1.7E-13 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_2c10150 7e09665ae8e8912060fe023cea3b47d0 650 PRINTS PR00344 Bacterial sensor protein C-terminal signature 632 645 1.7E-13 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_2c10150 7e09665ae8e8912060fe023cea3b47d0 650 PRINTS PR00344 Bacterial sensor protein C-terminal signature 593 603 1.7E-13 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_2c10150 7e09665ae8e8912060fe023cea3b47d0 650 PRINTS PR00344 Bacterial sensor protein C-terminal signature 608 626 1.7E-13 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_2c10150 7e09665ae8e8912060fe023cea3b47d0 650 SMART SM01080 37 322 5.2E-78 T 12-10-2018 IPR007890 CHASE2 VAPA_2c10150 7e09665ae8e8912060fe023cea3b47d0 650 SUPERFAMILY SSF47384 409 487 2.16E-5 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 VAPA_2c10150 7e09665ae8e8912060fe023cea3b47d0 650 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 541 646 4.7E-20 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase VAPA_2c10150 7e09665ae8e8912060fe023cea3b47d0 650 SUPERFAMILY SSF55874 484 644 1.13E-34 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_2c10150 7e09665ae8e8912060fe023cea3b47d0 650 Gene3D G3DSA:3.30.565.10 490 648 8.5E-34 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_1c51600 33661e95055f4b839c8fb4ff5d57a90f 300 Gene3D G3DSA:3.40.190.10 88 285 5.9E-63 T 12-10-2018 VAPA_1c51600 33661e95055f4b839c8fb4ff5d57a90f 300 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 4.1E-20 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c51600 33661e95055f4b839c8fb4ff5d57a90f 300 SUPERFAMILY SSF46785 1 85 2.11E-21 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c51600 33661e95055f4b839c8fb4ff5d57a90f 300 SUPERFAMILY SSF53850 89 294 1.33E-40 T 12-10-2018 VAPA_1c51600 33661e95055f4b839c8fb4ff5d57a90f 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.6E-9 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c51600 33661e95055f4b839c8fb4ff5d57a90f 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.6E-9 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c51600 33661e95055f4b839c8fb4ff5d57a90f 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.6E-9 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c51600 33661e95055f4b839c8fb4ff5d57a90f 300 Gene3D G3DSA:1.10.10.10 1 84 9.6E-28 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c51600 33661e95055f4b839c8fb4ff5d57a90f 300 Pfam PF03466 LysR substrate binding domain 87 292 7.3E-43 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_1c51600 33661e95055f4b839c8fb4ff5d57a90f 300 Gene3D G3DSA:3.40.190.10 162 267 5.9E-63 T 12-10-2018 VAPA_2c00110 6b5741206d463835d68715ea9f7169a1 284 Gene3D G3DSA:1.10.10.60 235 282 1.9E-9 T 12-10-2018 VAPA_2c00110 6b5741206d463835d68715ea9f7169a1 284 Gene3D G3DSA:1.10.10.60 173 234 1.8E-13 T 12-10-2018 VAPA_2c00110 6b5741206d463835d68715ea9f7169a1 284 SUPERFAMILY SSF51215 27 154 1.96E-13 T 12-10-2018 IPR037923 Transcription regulator HTH-like VAPA_2c00110 6b5741206d463835d68715ea9f7169a1 284 SUPERFAMILY SSF46689 229 277 8.06E-8 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 VAPA_2c00110 6b5741206d463835d68715ea9f7169a1 284 SMART SM00342 192 274 4.3E-24 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 VAPA_2c00110 6b5741206d463835d68715ea9f7169a1 284 Pfam PF02311 AraC-like ligand binding domain 24 147 5.8E-18 T 12-10-2018 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 VAPA_2c00110 6b5741206d463835d68715ea9f7169a1 284 SUPERFAMILY SSF46689 178 226 7.17E-9 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 VAPA_2c00110 6b5741206d463835d68715ea9f7169a1 284 Pfam PF12833 Helix-turn-helix domain 198 275 1.9E-19 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 VAPA_1c32050 1b9847716000c8fe7f252df9370ef58d 308 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 5.7E-18 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c32050 1b9847716000c8fe7f252df9370ef58d 308 Gene3D G3DSA:3.40.190.290 91 297 1.6E-38 T 12-10-2018 VAPA_1c32050 1b9847716000c8fe7f252df9370ef58d 308 Pfam PF03466 LysR substrate binding domain 85 284 2.0E-33 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_1c32050 1b9847716000c8fe7f252df9370ef58d 308 Gene3D G3DSA:1.10.10.10 1 90 5.2E-25 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c32050 1b9847716000c8fe7f252df9370ef58d 308 SUPERFAMILY SSF46785 1 84 9.25E-20 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c32050 1b9847716000c8fe7f252df9370ef58d 308 SUPERFAMILY SSF53850 87 296 1.55E-32 T 12-10-2018 VAPA_1c16530 d9f1cff768e0a5ec4d013d6add58e15a 387 Pfam PF01266 FAD dependent oxidoreductase 12 354 1.6E-48 T 12-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 VAPA_1c16530 d9f1cff768e0a5ec4d013d6add58e15a 387 SUPERFAMILY SSF51905 12 374 7.12E-42 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c16530 d9f1cff768e0a5ec4d013d6add58e15a 387 Gene3D G3DSA:3.30.9.10 91 315 1.3E-119 T 12-10-2018 VAPA_1c16530 d9f1cff768e0a5ec4d013d6add58e15a 387 Gene3D G3DSA:3.50.50.60 12 355 1.3E-119 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c26590 9a3298d0f3e115ebc91158d961133dfd 477 Pfam PF07690 Major Facilitator Superfamily 30 429 1.2E-44 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 VAPA_1c26590 9a3298d0f3e115ebc91158d961133dfd 477 Gene3D G3DSA:1.20.1250.20 279 472 6.6E-16 T 12-10-2018 VAPA_1c26590 9a3298d0f3e115ebc91158d961133dfd 477 SUPERFAMILY SSF103473 20 469 7.32E-57 T 12-10-2018 IPR036259 MFS transporter superfamily VAPA_1c26590 9a3298d0f3e115ebc91158d961133dfd 477 Gene3D G3DSA:1.20.1720.10 27 237 3.4E-40 T 12-10-2018 VAPA_1c31300 4ccfac192ed98c7a29636f53f3c05856 320 Gene3D G3DSA:3.30.70.520 10 312 1.6E-117 T 12-10-2018 IPR023447 Formylmethanofuran: tetrahydromethanopterin formyltransferase Ftr, ferredoxin-like superfamily VAPA_1c31300 4ccfac192ed98c7a29636f53f3c05856 320 Pfam PF02741 FTR, proximal lobe 156 312 9.0E-60 T 12-10-2018 IPR002770 Formylmethanofuran: tetrahydromethanopterin formyltransferase Ftr, C-terminal GO:0006730|GO:0016740 VAPA_1c31300 4ccfac192ed98c7a29636f53f3c05856 320 SUPERFAMILY SSF55112 155 313 6.91E-57 T 12-10-2018 IPR023447 Formylmethanofuran: tetrahydromethanopterin formyltransferase Ftr, ferredoxin-like superfamily VAPA_1c31300 4ccfac192ed98c7a29636f53f3c05856 320 Pfam PF01913 Formylmethanofuran-tetrahydromethanopterin formyltransferase 8 153 6.9E-62 T 12-10-2018 IPR022667 Formylmethanofuran: tetrahydromethanopterin formyltransferase Ftr, N-terminal GO:0006730|GO:0016740 VAPA_1c31300 4ccfac192ed98c7a29636f53f3c05856 320 TIGRFAM TIGR03119 one_C_fhcD: formylmethanofuran--tetrahydromethanopterin N-formyltransferase 14 312 1.3E-127 T 12-10-2018 IPR014053 Formylmethanofuran: tetrahydromethanopterin formyltransferase Ftr GO:0006730|GO:0030270 VAPA_1c31300 4ccfac192ed98c7a29636f53f3c05856 320 Hamap MF_00579 Formylmethanofuran--tetrahydromethanopterin formyltransferase [ftr]. 7 313 45.45 T 12-10-2018 IPR014053 Formylmethanofuran: tetrahydromethanopterin formyltransferase Ftr GO:0006730|GO:0030270 VAPA_1c31300 4ccfac192ed98c7a29636f53f3c05856 320 PIRSF PIRSF006414 7 314 2.2E-109 T 12-10-2018 IPR014053 Formylmethanofuran: tetrahydromethanopterin formyltransferase Ftr GO:0006730|GO:0030270 VAPA_1c31300 4ccfac192ed98c7a29636f53f3c05856 320 SUPERFAMILY SSF55112 8 154 2.62E-63 T 12-10-2018 IPR023447 Formylmethanofuran: tetrahydromethanopterin formyltransferase Ftr, ferredoxin-like superfamily VAPA_1c31300 4ccfac192ed98c7a29636f53f3c05856 320 Gene3D G3DSA:3.30.70.520 23 171 1.6E-117 T 12-10-2018 IPR023447 Formylmethanofuran: tetrahydromethanopterin formyltransferase Ftr, ferredoxin-like superfamily VAPA_1c08970 97c31f6701bd584b4304eaf56b5ffaf4 336 Gene3D G3DSA:3.40.190.10 136 261 1.6E-105 T 12-10-2018 VAPA_1c08970 97c31f6701bd584b4304eaf56b5ffaf4 336 PIRSF PIRSF017082 4 335 9.5E-76 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c08970 97c31f6701bd584b4304eaf56b5ffaf4 336 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 57 332 5.1E-78 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c08970 97c31f6701bd584b4304eaf56b5ffaf4 336 SUPERFAMILY SSF53850 123 296 4.54E-10 T 12-10-2018 VAPA_1c08970 97c31f6701bd584b4304eaf56b5ffaf4 336 Gene3D G3DSA:3.40.190.150 38 326 1.6E-105 T 12-10-2018 VAPA_1c23610 221fe2c14634e0db4933e0df6684fc33 272 Pfam PF04079 Segregation and condensation complex subunit ScpB 9 165 8.2E-46 T 12-10-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 VAPA_1c23610 221fe2c14634e0db4933e0df6684fc33 272 TIGRFAM TIGR00281 TIGR00281: segregation and condensation protein B 7 174 2.1E-30 T 12-10-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 VAPA_1c23610 221fe2c14634e0db4933e0df6684fc33 272 SUPERFAMILY SSF46785 83 158 1.44E-22 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c23610 221fe2c14634e0db4933e0df6684fc33 272 Gene3D G3DSA:1.10.10.10 2 80 1.8E-9 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c23610 221fe2c14634e0db4933e0df6684fc33 272 SUPERFAMILY SSF46785 1 80 2.58E-17 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c23610 221fe2c14634e0db4933e0df6684fc33 272 Gene3D G3DSA:1.10.10.10 81 176 8.4E-32 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c22390 26bba275f26d2b8fa484506e3128c0bf 442 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 140 166 8.9E-41 T 12-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 VAPA_1c22390 26bba275f26d2b8fa484506e3128c0bf 442 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 72 92 8.9E-41 T 12-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 VAPA_1c22390 26bba275f26d2b8fa484506e3128c0bf 442 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 182 204 8.9E-41 T 12-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 VAPA_1c22390 26bba275f26d2b8fa484506e3128c0bf 442 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 94 114 8.9E-41 T 12-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 VAPA_1c22390 26bba275f26d2b8fa484506e3128c0bf 442 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 51 66 8.9E-41 T 12-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 VAPA_1c22390 26bba275f26d2b8fa484506e3128c0bf 442 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 21 46 8.9E-41 T 12-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 VAPA_1c22390 26bba275f26d2b8fa484506e3128c0bf 442 Gene3D G3DSA:3.90.380.10 20 422 5.6E-105 T 12-10-2018 VAPA_1c22390 26bba275f26d2b8fa484506e3128c0bf 442 SUPERFAMILY SSF50022 8 156 3.14E-47 T 12-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 VAPA_1c22390 26bba275f26d2b8fa484506e3128c0bf 442 Pfam PF00848 Ring hydroxylating alpha subunit (catalytic domain) 195 393 3.6E-11 T 12-10-2018 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0044237|GO:0051537|GO:0055114 VAPA_1c22390 26bba275f26d2b8fa484506e3128c0bf 442 SUPERFAMILY SSF55961 156 434 3.14E-49 T 12-10-2018 VAPA_1c22390 26bba275f26d2b8fa484506e3128c0bf 442 Pfam PF00355 Rieske [2Fe-2S] domain 37 119 8.2E-19 T 12-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 VAPA_1c22390 26bba275f26d2b8fa484506e3128c0bf 442 Gene3D G3DSA:2.102.10.10 34 165 5.6E-105 T 12-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 VAPA_1c25800 057954155b711e3c9e0a8d346d734eb4 429 PIRSF PIRSF001434 1 428 9.5E-132 T 12-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 VAPA_1c25800 057954155b711e3c9e0a8d346d734eb4 429 SUPERFAMILY SSF53383 5 425 1.33E-129 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase VAPA_1c25800 057954155b711e3c9e0a8d346d734eb4 429 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 200 214 - T 12-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 VAPA_1c25800 057954155b711e3c9e0a8d346d734eb4 429 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 8 424 4.6E-143 T 12-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 VAPA_1c25800 057954155b711e3c9e0a8d346d734eb4 429 Gene3D G3DSA:3.40.640.10 5 289 1.7E-103 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 VAPA_1c25800 057954155b711e3c9e0a8d346d734eb4 429 TIGRFAM TIGR01326 OAH_OAS_sulfhy: O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase 6 425 2.1E-196 T 12-10-2018 IPR006235 O-acetylhomoserine/O-acetylserine sulfhydrylase GO:0006520|GO:0016765 VAPA_1c25800 057954155b711e3c9e0a8d346d734eb4 429 Gene3D G3DSA:3.90.1150.10 293 429 4.2E-51 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 VAPA_1c15820 dc8c2d48b1294c658f1ab171521d8f01 732 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 454 597 3.5E-19 T 12-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 VAPA_1c15820 dc8c2d48b1294c658f1ab171521d8f01 732 Gene3D G3DSA:3.40.50.970 448 628 1.6E-14 T 12-10-2018 VAPA_1c15820 dc8c2d48b1294c658f1ab171521d8f01 732 SUPERFAMILY SSF52518 19 216 5.89E-28 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold VAPA_1c15820 dc8c2d48b1294c658f1ab171521d8f01 732 SUPERFAMILY SSF52518 420 646 1.57E-31 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold VAPA_1c15820 dc8c2d48b1294c658f1ab171521d8f01 732 Gene3D G3DSA:3.40.50.970 3 205 6.5E-24 T 12-10-2018 VAPA_1c41140 4cc70ddade893398bebe8594c25fc745 155 ProSitePatterns PS00519 AsnC-type HTH domain signature. 22 48 - T 12-10-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site VAPA_1c41140 4cc70ddade893398bebe8594c25fc745 155 Gene3D G3DSA:1.10.10.10 1 55 8.5E-27 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c41140 4cc70ddade893398bebe8594c25fc745 155 SUPERFAMILY SSF46785 4 63 4.09E-20 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c41140 4cc70ddade893398bebe8594c25fc745 155 SUPERFAMILY SSF54909 66 151 6.3E-18 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel VAPA_1c41140 4cc70ddade893398bebe8594c25fc745 155 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 20 31 1.0E-19 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 VAPA_1c41140 4cc70ddade893398bebe8594c25fc745 155 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 4 20 1.0E-19 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 VAPA_1c41140 4cc70ddade893398bebe8594c25fc745 155 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 31 50 1.0E-19 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 VAPA_1c41140 4cc70ddade893398bebe8594c25fc745 155 Gene3D G3DSA:3.30.70.920 56 149 6.7E-22 T 12-10-2018 VAPA_1c41140 4cc70ddade893398bebe8594c25fc745 155 Pfam PF01037 Lrp/AsnC ligand binding domain 70 144 1.1E-17 T 12-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain VAPA_1c41140 4cc70ddade893398bebe8594c25fc745 155 SMART SM00344 4 113 8.2E-47 T 12-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 VAPA_1c41140 4cc70ddade893398bebe8594c25fc745 155 Pfam PF13412 Winged helix-turn-helix DNA-binding 4 50 1.2E-20 T 12-10-2018 VAPA_2c03640 b75477db56f5ccd924aca6b74096309e 239 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 213 235 2.4E-6 T 12-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal VAPA_2c03640 b75477db56f5ccd924aca6b74096309e 239 SUPERFAMILY SSF52540 3 236 3.29E-58 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_2c03640 b75477db56f5ccd924aca6b74096309e 239 SMART SM00382 28 213 2.4E-10 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_2c03640 b75477db56f5ccd924aca6b74096309e 239 Gene3D G3DSA:3.40.50.300 1 237 2.0E-55 T 12-10-2018 VAPA_2c03640 b75477db56f5ccd924aca6b74096309e 239 Pfam PF00005 ABC transporter 20 164 1.9E-24 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c36780 89c51641e41ce548aa0fe5648d5b13b3 112 SUPERFAMILY SSF46785 18 110 7.5E-19 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c36780 89c51641e41ce548aa0fe5648d5b13b3 112 Gene3D G3DSA:1.10.10.10 9 112 3.0E-21 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c36780 89c51641e41ce548aa0fe5648d5b13b3 112 Pfam PF01638 HxlR-like helix-turn-helix 27 108 1.7E-8 T 12-10-2018 IPR002577 Helix-turn-helix, HxlR type VAPA_1c39030 0ba5b23dbd252e89cf8d5397a7a1d76d 165 SUPERFAMILY SSF55826 9 161 2.22E-38 T 12-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 VAPA_1c39030 0ba5b23dbd252e89cf8d5397a7a1d76d 165 Gene3D G3DSA:3.90.960.10 5 163 2.1E-43 T 12-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 VAPA_1c39030 0ba5b23dbd252e89cf8d5397a7a1d76d 165 Pfam PF04073 Aminoacyl-tRNA editing domain 39 149 3.3E-24 T 12-10-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 VAPA_1c39030 0ba5b23dbd252e89cf8d5397a7a1d76d 165 PIRSF PIRSF006181 7 164 6.0E-45 T 12-10-2018 IPR004369 Prolyl-tRNA editing protein, YbaK/EbsC VAPA_1c07560 e7ba2daa41ab1c8ae3cfa838c603dee1 229 Gene3D G3DSA:3.40.50.1820 5 222 2.1E-60 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c07560 e7ba2daa41ab1c8ae3cfa838c603dee1 229 SUPERFAMILY SSF53474 7 222 2.61E-33 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c07560 e7ba2daa41ab1c8ae3cfa838c603dee1 229 Pfam PF01738 Dienelactone hydrolase family 27 216 3.3E-6 T 12-10-2018 IPR002925 Dienelactone hydrolase GO:0016787 VAPA_2c03930 c46a68b76030e573d45c01bfafcbc1fd 199 Pfam PF00881 Nitroreductase family 30 196 1.7E-25 T 12-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 VAPA_2c03930 c46a68b76030e573d45c01bfafcbc1fd 199 Gene3D G3DSA:3.40.109.10 3 198 3.7E-58 T 12-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 VAPA_2c03930 c46a68b76030e573d45c01bfafcbc1fd 199 SUPERFAMILY SSF55469 23 198 1.31E-29 T 12-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 VAPA_1c21400 90edbf10eb179b6a9f16282e312fa750 212 Gene3D G3DSA:3.40.30.10 1 86 2.7E-23 T 12-10-2018 VAPA_1c21400 90edbf10eb179b6a9f16282e312fa750 212 Pfam PF02798 Glutathione S-transferase, N-terminal domain 1 74 1.8E-13 T 12-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 VAPA_1c21400 90edbf10eb179b6a9f16282e312fa750 212 Gene3D G3DSA:1.20.1050.10 87 212 2.1E-51 T 12-10-2018 VAPA_1c21400 90edbf10eb179b6a9f16282e312fa750 212 Pfam PF13410 Glutathione S-transferase, C-terminal domain 140 171 1.3E-5 T 12-10-2018 VAPA_1c21400 90edbf10eb179b6a9f16282e312fa750 212 SUPERFAMILY SSF52833 1 89 7.2E-22 T 12-10-2018 IPR036249 Thioredoxin-like superfamily VAPA_1c21400 90edbf10eb179b6a9f16282e312fa750 212 SUPERFAMILY SSF47616 81 210 3.98E-32 T 12-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily VAPA_1c21400 90edbf10eb179b6a9f16282e312fa750 212 TIGRFAM TIGR01262 maiA: maleylacetoacetate isomerase 2 210 6.2E-80 T 12-10-2018 IPR005955 Glutathione S-transferases, class Zeta GO:0003824|GO:0005737|GO:0009072 Reactome: R-HSA-156590|Reactome: R-HSA-204174|Reactome: R-HSA-71182 VAPA_1c04910 2d96690b586da829a79d51728a6a4843 827 PIRSF PIRSF000460 9 826 5.6E-233 T 12-10-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 VAPA_1c04910 2d96690b586da829a79d51728a6a4843 827 TIGRFAM TIGR02093 P_ylase: glycogen/starch/alpha-glucan phosphorylases 15 820 0.0 T 12-10-2018 IPR011833 Glycogen/starch/alpha-glucan phosphorylase GO:0004645|GO:0005975|GO:0030170 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 VAPA_1c04910 2d96690b586da829a79d51728a6a4843 827 SUPERFAMILY SSF53756 11 824 0.0 T 12-10-2018 VAPA_1c04910 2d96690b586da829a79d51728a6a4843 827 ProSitePatterns PS00102 Phosphorylase pyridoxal-phosphate attachment site. 665 677 - T 12-10-2018 IPR035090 Phosphorylase pyridoxal-phosphate attachment site KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 VAPA_1c04910 2d96690b586da829a79d51728a6a4843 827 Gene3D G3DSA:3.40.50.2000 478 806 2.0E-144 T 12-10-2018 VAPA_1c04910 2d96690b586da829a79d51728a6a4843 827 Gene3D G3DSA:3.40.50.2000 4 477 1.8E-208 T 12-10-2018 VAPA_1c04910 2d96690b586da829a79d51728a6a4843 827 Pfam PF00343 Carbohydrate phosphorylase 103 820 0.0 T 12-10-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 VAPA_1c46790 b06052c95805ebebc4c08c87dd737d56 373 Pfam PF07728 AAA domain (dynein-related subfamily) 86 226 1.7E-34 T 12-10-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 VAPA_1c46790 b06052c95805ebebc4c08c87dd737d56 373 SMART SM00382 82 235 0.0023 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c46790 b06052c95805ebebc4c08c87dd737d56 373 Gene3D G3DSA:3.40.50.300 67 241 3.3E-21 T 12-10-2018 VAPA_1c46790 b06052c95805ebebc4c08c87dd737d56 373 SUPERFAMILY SSF52540 65 324 4.04E-21 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c16330 cbee26bb970347db2718df0cf8edf091 810 Pfam PF00580 UvrD/REP helicase N-terminal domain 27 297 1.2E-72 T 12-10-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 VAPA_1c16330 cbee26bb970347db2718df0cf8edf091 810 Gene3D G3DSA:1.10.10.160 131 203 7.2E-91 T 12-10-2018 IPR013986 DExx box DNA helicase domain superfamily VAPA_1c16330 cbee26bb970347db2718df0cf8edf091 810 Pfam PF13361 UvrD-like helicase C-terminal domain 303 673 1.1E-72 T 12-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 VAPA_1c16330 cbee26bb970347db2718df0cf8edf091 810 SUPERFAMILY SSF52540 22 696 6.06E-174 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c16330 cbee26bb970347db2718df0cf8edf091 810 Gene3D G3DSA:3.40.50.300 27 297 7.2E-91 T 12-10-2018 VAPA_2c03490 f74bccbd30d1a8b32d9e25202239a090 142 SMART SM00749 8 71 23.0 T 12-10-2018 IPR014004 Transport-associated and nodulation domain, bacteria VAPA_2c03490 f74bccbd30d1a8b32d9e25202239a090 142 SMART SM00749 79 142 0.028 T 12-10-2018 IPR014004 Transport-associated and nodulation domain, bacteria VAPA_2c03490 f74bccbd30d1a8b32d9e25202239a090 142 Pfam PF04972 BON domain 3 69 2.4E-16 T 12-10-2018 IPR007055 BON domain VAPA_2c03490 f74bccbd30d1a8b32d9e25202239a090 142 Pfam PF04972 BON domain 77 141 2.9E-12 T 12-10-2018 IPR007055 BON domain VAPA_1c36010 b16507f8685588dfe258fdab301ab4f3 594 SUPERFAMILY SSF52540 346 592 5.12E-90 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c36010 b16507f8685588dfe258fdab301ab4f3 594 SMART SM00382 381 567 2.4E-17 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c36010 b16507f8685588dfe258fdab301ab4f3 594 Gene3D G3DSA:3.40.50.300 348 593 6.5E-93 T 12-10-2018 VAPA_1c36010 b16507f8685588dfe258fdab301ab4f3 594 Pfam PF00005 ABC transporter 372 521 4.7E-33 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c36010 b16507f8685588dfe258fdab301ab4f3 594 Gene3D G3DSA:1.20.1560.10 14 339 2.4E-75 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 VAPA_1c36010 b16507f8685588dfe258fdab301ab4f3 594 SUPERFAMILY SSF90123 20 333 2.09E-68 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 VAPA_1c36010 b16507f8685588dfe258fdab301ab4f3 594 ProSitePatterns PS00211 ABC transporters family signature. 493 507 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_1c36010 b16507f8685588dfe258fdab301ab4f3 594 Pfam PF00664 ABC transporter transmembrane region 32 303 1.4E-49 T 12-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 VAPA_1c19400 15b2b52866dcc1ca756e6852dcb12c14 402 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 246 358 1.4E-32 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal VAPA_1c19400 15b2b52866dcc1ca756e6852dcb12c14 402 Gene3D G3DSA:3.40.47.10 252 402 1.0E-47 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 VAPA_1c19400 15b2b52866dcc1ca756e6852dcb12c14 402 SMART SM00825 Beta-ketoacyl synthase 5 402 1.7E-16 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain VAPA_1c19400 15b2b52866dcc1ca756e6852dcb12c14 402 SUPERFAMILY SSF53901 4 400 3.22E-61 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 VAPA_1c19400 15b2b52866dcc1ca756e6852dcb12c14 402 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 4 238 4.1E-46 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal VAPA_1c19400 15b2b52866dcc1ca756e6852dcb12c14 402 Gene3D G3DSA:3.40.47.10 1 246 3.7E-67 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 VAPA_1c47920 83b15d94c08734eba7f738d79c19342a 223 Pfam PF04542 Sigma-70 region 2 39 108 1.5E-14 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 VAPA_1c47920 83b15d94c08734eba7f738d79c19342a 223 Gene3D G3DSA:1.10.10.10 129 214 1.8E-16 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c47920 83b15d94c08734eba7f738d79c19342a 223 Gene3D G3DSA:1.10.1740.10 13 127 1.4E-21 T 12-10-2018 VAPA_1c47920 83b15d94c08734eba7f738d79c19342a 223 SUPERFAMILY SSF88659 150 213 2.8E-13 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like VAPA_1c47920 83b15d94c08734eba7f738d79c19342a 223 SUPERFAMILY SSF88946 17 120 8.63E-24 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 VAPA_1c47920 83b15d94c08734eba7f738d79c19342a 223 Pfam PF08281 Sigma-70, region 4 156 208 1.6E-10 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 VAPA_1c47920 83b15d94c08734eba7f738d79c19342a 223 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 35 211 6.9E-25 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 VAPA_1c37530 9a7bf775a72e88c9214bac75dc3e84fe 307 Gene3D G3DSA:3.40.50.720 11 303 5.5E-75 T 12-10-2018 VAPA_1c37530 9a7bf775a72e88c9214bac75dc3e84fe 307 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 11 188 5.7E-5 T 12-10-2018 VAPA_1c37530 9a7bf775a72e88c9214bac75dc3e84fe 307 SUPERFAMILY SSF51735 6 246 7.42E-66 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c37530 9a7bf775a72e88c9214bac75dc3e84fe 307 Pfam PF00106 short chain dehydrogenase 12 206 1.6E-45 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c37530 9a7bf775a72e88c9214bac75dc3e84fe 307 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 155 183 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 VAPA_1c37530 9a7bf775a72e88c9214bac75dc3e84fe 307 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 95 106 2.7E-8 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c37530 9a7bf775a72e88c9214bac75dc3e84fe 307 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 168 187 2.7E-8 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c37530 9a7bf775a72e88c9214bac75dc3e84fe 307 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 148 156 2.7E-8 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c37530 9a7bf775a72e88c9214bac75dc3e84fe 307 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 12 29 3.0E-23 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c37530 9a7bf775a72e88c9214bac75dc3e84fe 307 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 168 187 3.0E-23 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c37530 9a7bf775a72e88c9214bac75dc3e84fe 307 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 95 106 3.0E-23 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c37530 9a7bf775a72e88c9214bac75dc3e84fe 307 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 142 158 3.0E-23 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c37530 9a7bf775a72e88c9214bac75dc3e84fe 307 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 189 206 3.0E-23 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c07900 cf4a21080ce8812b203658cab64e437e 1044 PRINTS PR00702 Acriflavin resistance protein family signature 550 567 3.1E-25 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 VAPA_2c07900 cf4a21080ce8812b203658cab64e437e 1044 PRINTS PR00702 Acriflavin resistance protein family signature 40 58 3.1E-25 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 VAPA_2c07900 cf4a21080ce8812b203658cab64e437e 1044 PRINTS PR00702 Acriflavin resistance protein family signature 12 36 3.1E-25 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 VAPA_2c07900 cf4a21080ce8812b203658cab64e437e 1044 PRINTS PR00702 Acriflavin resistance protein family signature 360 381 3.1E-25 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 VAPA_2c07900 cf4a21080ce8812b203658cab64e437e 1044 PRINTS PR00702 Acriflavin resistance protein family signature 333 356 3.1E-25 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 VAPA_2c07900 cf4a21080ce8812b203658cab64e437e 1044 PRINTS PR00702 Acriflavin resistance protein family signature 388 412 3.1E-25 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 VAPA_2c07900 cf4a21080ce8812b203658cab64e437e 1044 Gene3D G3DSA:3.30.70.1440 670 867 3.6E-254 T 12-10-2018 VAPA_2c07900 cf4a21080ce8812b203658cab64e437e 1044 Gene3D G3DSA:3.30.70.1430 42 817 3.6E-254 T 12-10-2018 VAPA_2c07900 cf4a21080ce8812b203658cab64e437e 1044 Gene3D G3DSA:3.30.70.1430 567 669 3.6E-254 T 12-10-2018 VAPA_2c07900 cf4a21080ce8812b203658cab64e437e 1044 SUPERFAMILY SSF82714 185 268 4.45E-17 T 12-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains VAPA_2c07900 cf4a21080ce8812b203658cab64e437e 1044 Gene3D G3DSA:3.30.2090.10 182 273 3.6E-254 T 12-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains VAPA_2c07900 cf4a21080ce8812b203658cab64e437e 1044 Pfam PF00873 AcrB/AcrD/AcrF family 6 1034 2.0E-229 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 VAPA_2c07900 cf4a21080ce8812b203658cab64e437e 1044 TIGRFAM TIGR00914 2A0601: heavy metal efflux pump, CzcA family 1 1041 0.0 T 12-10-2018 IPR004763 Cation efflux system CzcA/CusA/SilA/NccA/HelA/CnrA GO:0006812|GO:0008324|GO:0016021 VAPA_2c07900 cf4a21080ce8812b203658cab64e437e 1044 SUPERFAMILY SSF82866 294 503 8.37E-38 T 12-10-2018 VAPA_2c07900 cf4a21080ce8812b203658cab64e437e 1044 SUPERFAMILY SSF82693 45 126 8.37E-20 T 12-10-2018 VAPA_2c07900 cf4a21080ce8812b203658cab64e437e 1044 SUPERFAMILY SSF82866 803 1039 5.49E-46 T 12-10-2018 VAPA_2c07900 cf4a21080ce8812b203658cab64e437e 1044 Gene3D G3DSA:1.20.1640.10 15 511 3.6E-254 T 12-10-2018 VAPA_2c07900 cf4a21080ce8812b203658cab64e437e 1044 Gene3D G3DSA:3.30.70.1320 135 327 3.6E-254 T 12-10-2018 VAPA_2c07900 cf4a21080ce8812b203658cab64e437e 1044 SUPERFAMILY SSF82714 721 805 5.36E-16 T 12-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains VAPA_2c07900 cf4a21080ce8812b203658cab64e437e 1044 Gene3D G3DSA:1.20.1640.10 512 1030 3.6E-254 T 12-10-2018 VAPA_2c07900 cf4a21080ce8812b203658cab64e437e 1044 SUPERFAMILY SSF82693 137 327 1.23E-19 T 12-10-2018 VAPA_2c07900 cf4a21080ce8812b203658cab64e437e 1044 Gene3D G3DSA:3.30.2090.10 721 809 3.6E-254 T 12-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains VAPA_1c50520 e1955fd570195268b360b5772a18c5cf 139 SUPERFAMILY SSF46604 88 136 1.7E-9 T 12-10-2018 IPR036794 ATP synthase delta/epsilon subunit, C-terminal domain superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 VAPA_1c50520 e1955fd570195268b360b5772a18c5cf 139 Hamap MF_00530 ATP synthase epsilon chain [atpC]. 3 131 20.892 T 12-10-2018 IPR001469 ATP synthase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 VAPA_1c50520 e1955fd570195268b360b5772a18c5cf 139 Gene3D G3DSA:1.20.5.440 91 133 3.6E-7 T 12-10-2018 VAPA_1c50520 e1955fd570195268b360b5772a18c5cf 139 Gene3D G3DSA:2.60.15.10 4 90 2.3E-31 T 12-10-2018 IPR036771 F0F1 ATP synthase delta/epsilon subunit, N-terminal Reactome: R-HSA-163210|Reactome: R-HSA-8949613 VAPA_1c50520 e1955fd570195268b360b5772a18c5cf 139 ProDom PD000944 ATP SYNTHASE ION EPSILON SUBUNIT HYDROLASE CF1 SYNTHESIS CHAIN HYDROGEN 10 90 6.0E-37 T 12-10-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 VAPA_1c50520 e1955fd570195268b360b5772a18c5cf 139 Pfam PF00401 ATP synthase, Delta/Epsilon chain, long alpha-helix domain 89 131 2.0E-5 T 12-10-2018 IPR020547 ATP synthase delta/epsilon subunit, C-terminal domain VAPA_1c50520 e1955fd570195268b360b5772a18c5cf 139 Pfam PF02823 ATP synthase, Delta/Epsilon chain, beta-sandwich domain 5 84 4.2E-30 T 12-10-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 VAPA_1c50520 e1955fd570195268b360b5772a18c5cf 139 SUPERFAMILY SSF51344 4 86 5.49E-25 T 12-10-2018 IPR036771 F0F1 ATP synthase delta/epsilon subunit, N-terminal Reactome: R-HSA-163210|Reactome: R-HSA-8949613 VAPA_1c50520 e1955fd570195268b360b5772a18c5cf 139 TIGRFAM TIGR01216 ATP_synt_epsi: ATP synthase F1, epsilon subunit 4 132 2.8E-42 T 12-10-2018 IPR001469 ATP synthase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 VAPA_1c19320 175b0c3d322e5660f331c53bfdc4343e 227 SUPERFAMILY SSF46689 20 103 3.14E-19 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 VAPA_1c19320 175b0c3d322e5660f331c53bfdc4343e 227 SUPERFAMILY SSF48498 99 209 5.04E-20 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily VAPA_1c19320 175b0c3d322e5660f331c53bfdc4343e 227 ProSitePatterns PS01081 TetR-type HTH domain signature. 44 75 - T 12-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site VAPA_1c19320 175b0c3d322e5660f331c53bfdc4343e 227 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 53 76 6.4E-10 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 VAPA_1c19320 175b0c3d322e5660f331c53bfdc4343e 227 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 32 45 6.4E-10 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 VAPA_1c19320 175b0c3d322e5660f331c53bfdc4343e 227 Pfam PF00440 Bacterial regulatory proteins, tetR family 33 78 1.2E-16 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 VAPA_1c19320 175b0c3d322e5660f331c53bfdc4343e 227 Gene3D G3DSA:1.10.10.60 14 73 2.0E-21 T 12-10-2018 VAPA_1c19320 175b0c3d322e5660f331c53bfdc4343e 227 Gene3D G3DSA:1.10.357.10 74 211 1.0E-31 T 12-10-2018 VAPA_1c43450 a7eeeb822ae0a7d2a58b9e65068b0ec6 581 Pfam PF08447 PAS fold 31 111 7.8E-14 T 12-10-2018 IPR013655 PAS fold-3 GO:0005515 VAPA_1c43450 a7eeeb822ae0a7d2a58b9e65068b0ec6 581 SUPERFAMILY SSF55785 21 114 1.24E-26 T 12-10-2018 IPR035965 PAS domain superfamily VAPA_1c43450 a7eeeb822ae0a7d2a58b9e65068b0ec6 581 SMART SM00283 269 516 1.6E-89 T 12-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 VAPA_1c43450 a7eeeb822ae0a7d2a58b9e65068b0ec6 581 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 328 484 1.5E-55 T 12-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 VAPA_1c43450 a7eeeb822ae0a7d2a58b9e65068b0ec6 581 Gene3D G3DSA:3.30.450.20 13 151 6.9E-26 T 12-10-2018 VAPA_1c43450 a7eeeb822ae0a7d2a58b9e65068b0ec6 581 SMART SM00091 8 74 1.7E-4 T 12-10-2018 IPR000014 PAS domain VAPA_1c43450 a7eeeb822ae0a7d2a58b9e65068b0ec6 581 Gene3D G3DSA:1.10.287.950 217 518 6.7E-89 T 12-10-2018 VAPA_1c43450 a7eeeb822ae0a7d2a58b9e65068b0ec6 581 SMART SM00086 80 121 0.0011 T 12-10-2018 IPR001610 PAC motif VAPA_1c43450 a7eeeb822ae0a7d2a58b9e65068b0ec6 581 SUPERFAMILY SSF58104 240 520 1.24E-75 T 12-10-2018 VAPA_1c43450 a7eeeb822ae0a7d2a58b9e65068b0ec6 581 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 23 114 1.1E-13 T 12-10-2018 IPR000014 PAS domain VAPA_1c43450 a7eeeb822ae0a7d2a58b9e65068b0ec6 581 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 396 425 3.2E-58 T 12-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 VAPA_1c43450 a7eeeb822ae0a7d2a58b9e65068b0ec6 581 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 444 473 3.2E-58 T 12-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 VAPA_1c43450 a7eeeb822ae0a7d2a58b9e65068b0ec6 581 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 290 319 3.2E-58 T 12-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 VAPA_1c43450 a7eeeb822ae0a7d2a58b9e65068b0ec6 581 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 367 394 3.2E-58 T 12-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 VAPA_1c17120 51d934edabf0af19a6c1c7a12d4ff3b0 373 Gene3D G3DSA:1.20.59.10 14 102 8.1E-28 T 12-10-2018 IPR036979 Chorismate mutase domain superfamily GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 VAPA_1c17120 51d934edabf0af19a6c1c7a12d4ff3b0 373 ProSitePatterns PS00858 Prephenate dehydratase signature 2. 319 326 - T 12-10-2018 IPR018528 Prephenate dehydratase, conserved site GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 VAPA_1c17120 51d934edabf0af19a6c1c7a12d4ff3b0 373 Pfam PF00800 Prephenate dehydratase 103 276 4.9E-56 T 12-10-2018 IPR001086 Prephenate dehydratase GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 VAPA_1c17120 51d934edabf0af19a6c1c7a12d4ff3b0 373 Gene3D G3DSA:3.40.190.10 106 275 9.7E-53 T 12-10-2018 VAPA_1c17120 51d934edabf0af19a6c1c7a12d4ff3b0 373 PIRSF PIRSF001500 12 373 2.7E-119 T 12-10-2018 IPR008242 Bifunctional P-protein, chorismate mutase/prephenate dehydratase GO:0004106|GO:0004664|GO:0005737|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 VAPA_1c17120 51d934edabf0af19a6c1c7a12d4ff3b0 373 SMART SM00830 22 101 1.2E-27 T 12-10-2018 IPR002701 Chorismate mutase II, prokaryotic-type GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 VAPA_1c17120 51d934edabf0af19a6c1c7a12d4ff3b0 373 Pfam PF01817 Chorismate mutase type II 22 98 8.1E-23 T 12-10-2018 IPR002701 Chorismate mutase II, prokaryotic-type GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 VAPA_1c17120 51d934edabf0af19a6c1c7a12d4ff3b0 373 Gene3D G3DSA:3.40.190.10 183 267 9.7E-53 T 12-10-2018 VAPA_1c17120 51d934edabf0af19a6c1c7a12d4ff3b0 373 SUPERFAMILY SSF55021 284 371 1.79E-24 T 12-10-2018 VAPA_1c17120 51d934edabf0af19a6c1c7a12d4ff3b0 373 Gene3D G3DSA:3.30.70.260 285 373 1.9E-25 T 12-10-2018 VAPA_1c17120 51d934edabf0af19a6c1c7a12d4ff3b0 373 SUPERFAMILY SSF53850 102 276 7.27E-52 T 12-10-2018 VAPA_1c17120 51d934edabf0af19a6c1c7a12d4ff3b0 373 SUPERFAMILY SSF48600 17 101 2.01E-20 T 12-10-2018 IPR036263 Chorismate mutase type II superfamily GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 VAPA_1c17120 51d934edabf0af19a6c1c7a12d4ff3b0 373 Pfam PF01842 ACT domain 292 357 4.4E-7 T 12-10-2018 IPR002912 ACT domain VAPA_1c17120 51d934edabf0af19a6c1c7a12d4ff3b0 373 TIGRFAM TIGR01807 CM_P2: chorismate mutase 18 91 2.3E-25 T 12-10-2018 IPR010957 Gamma/beta/epsilon proteobacterial P-protein, chorismate mutase domain GO:0004106|GO:0005737|GO:0009094 KEGG: 00400+5.4.99.5+4.2.1.51|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7432|MetaCyc: PWY-7626 VAPA_1c09260 97191afead3c65aec58c4d663b3fb86f 558 Gene3D G3DSA:3.50.50.60 493 557 1.6E-14 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c09260 97191afead3c65aec58c4d663b3fb86f 558 Gene3D G3DSA:3.50.50.60 97 321 4.9E-79 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c09260 97191afead3c65aec58c4d663b3fb86f 558 SUPERFAMILY SSF51905 109 553 2.78E-32 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c09260 97191afead3c65aec58c4d663b3fb86f 558 Gene3D G3DSA:3.30.70.2700 3 90 1.5E-21 T 12-10-2018 VAPA_1c09260 97191afead3c65aec58c4d663b3fb86f 558 PIRSF PIRSF038984 8 558 4.2E-227 T 12-10-2018 IPR028348 FAD dependent protein VAPA_1c27510 644254f64860d9f1d4f0946625413780 406 SUPERFAMILY SSF55874 230 394 6.81E-44 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_1c27510 644254f64860d9f1d4f0946625413780 406 SUPERFAMILY SSF52172 8 157 2.56E-33 T 12-10-2018 IPR011006 CheY-like superfamily VAPA_1c27510 644254f64860d9f1d4f0946625413780 406 Pfam PF00072 Response regulator receiver domain 10 121 4.2E-22 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_1c27510 644254f64860d9f1d4f0946625413780 406 Pfam PF00512 His Kinase A (phospho-acceptor) domain 168 239 5.6E-10 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 VAPA_1c27510 644254f64860d9f1d4f0946625413780 406 SMART SM00388 168 241 1.4E-6 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 VAPA_1c27510 644254f64860d9f1d4f0946625413780 406 Gene3D G3DSA:3.40.50.2300 2 136 3.3E-30 T 12-10-2018 VAPA_1c27510 644254f64860d9f1d4f0946625413780 406 SMART SM00387 286 396 1.8E-33 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase VAPA_1c27510 644254f64860d9f1d4f0946625413780 406 PRINTS PR00344 Bacterial sensor protein C-terminal signature 380 393 3.7E-16 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c27510 644254f64860d9f1d4f0946625413780 406 PRINTS PR00344 Bacterial sensor protein C-terminal signature 322 336 3.7E-16 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c27510 644254f64860d9f1d4f0946625413780 406 PRINTS PR00344 Bacterial sensor protein C-terminal signature 340 350 3.7E-16 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c27510 644254f64860d9f1d4f0946625413780 406 PRINTS PR00344 Bacterial sensor protein C-terminal signature 356 374 3.7E-16 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c27510 644254f64860d9f1d4f0946625413780 406 SMART SM00448 7 121 8.1E-27 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_1c27510 644254f64860d9f1d4f0946625413780 406 Gene3D G3DSA:1.10.287.130 158 240 2.9E-15 T 12-10-2018 VAPA_1c27510 644254f64860d9f1d4f0946625413780 406 Gene3D G3DSA:3.30.565.10 243 400 3.8E-41 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_1c27510 644254f64860d9f1d4f0946625413780 406 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 287 395 2.9E-23 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase VAPA_1c27510 644254f64860d9f1d4f0946625413780 406 SUPERFAMILY SSF47384 151 240 6.67E-15 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 VAPA_2c07660 0bf2850b3aa732fad384d6fcfc4ac9d3 114 SUPERFAMILY SSF46626 35 110 1.8E-16 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 VAPA_2c07660 0bf2850b3aa732fad384d6fcfc4ac9d3 114 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 36 109 1.8E-7 T 12-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 VAPA_2c07660 0bf2850b3aa732fad384d6fcfc4ac9d3 114 PRINTS PR00606 Class ID cytochrome C signature 51 64 1.8E-18 T 12-10-2018 IPR002324 Cytochrome c, class ID GO:0005506|GO:0009055|GO:0020037 VAPA_2c07660 0bf2850b3aa732fad384d6fcfc4ac9d3 114 PRINTS PR00606 Class ID cytochrome C signature 101 111 1.8E-18 T 12-10-2018 IPR002324 Cytochrome c, class ID GO:0005506|GO:0009055|GO:0020037 VAPA_2c07660 0bf2850b3aa732fad384d6fcfc4ac9d3 114 PRINTS PR00606 Class ID cytochrome C signature 74 87 1.8E-18 T 12-10-2018 IPR002324 Cytochrome c, class ID GO:0005506|GO:0009055|GO:0020037 VAPA_2c07660 0bf2850b3aa732fad384d6fcfc4ac9d3 114 PRINTS PR00606 Class ID cytochrome C signature 89 99 1.8E-18 T 12-10-2018 IPR002324 Cytochrome c, class ID GO:0005506|GO:0009055|GO:0020037 VAPA_2c07660 0bf2850b3aa732fad384d6fcfc4ac9d3 114 PRINTS PR00606 Class ID cytochrome C signature 36 49 1.8E-18 T 12-10-2018 IPR002324 Cytochrome c, class ID GO:0005506|GO:0009055|GO:0020037 VAPA_2c07660 0bf2850b3aa732fad384d6fcfc4ac9d3 114 Gene3D G3DSA:1.10.760.10 32 112 2.5E-26 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 VAPA_1c33360 2c1f11522e6a58510c3e2ba48e68875f 113 SMART SM00418 11 89 4.2E-14 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 VAPA_1c33360 2c1f11522e6a58510c3e2ba48e68875f 113 SUPERFAMILY SSF46785 1 104 3.15E-25 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c33360 2c1f11522e6a58510c3e2ba48e68875f 113 Gene3D G3DSA:1.10.10.10 4 111 2.8E-27 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c33360 2c1f11522e6a58510c3e2ba48e68875f 113 Pfam PF12840 Helix-turn-helix domain 10 69 1.1E-12 T 12-10-2018 VAPA_1c33360 2c1f11522e6a58510c3e2ba48e68875f 113 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 45 60 1.8E-5 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 VAPA_1c33360 2c1f11522e6a58510c3e2ba48e68875f 113 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 60 75 1.8E-5 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 VAPA_1c33360 2c1f11522e6a58510c3e2ba48e68875f 113 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 13 28 1.8E-5 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 VAPA_1c16920 b813c205291c232fd7d75a3b0e5ad241 404 PIRSF PIRSF010256 7 399 2.2E-85 T 12-10-2018 IPR011195 Uncharacterised conserved protein UCP010256 VAPA_1c16920 b813c205291c232fd7d75a3b0e5ad241 404 SUPERFAMILY SSF53300 226 355 2.74E-13 T 12-10-2018 IPR036465 von Willebrand factor A-like domain superfamily VAPA_1c16920 b813c205291c232fd7d75a3b0e5ad241 404 Gene3D G3DSA:3.40.50.410 228 350 1.2E-6 T 12-10-2018 IPR036465 von Willebrand factor A-like domain superfamily VAPA_1c16920 b813c205291c232fd7d75a3b0e5ad241 404 Pfam PF05762 VWA domain containing CoxE-like protein 180 388 2.8E-50 T 12-10-2018 IPR008912 Uncharacterised protein family CoxE-like VAPA_1c01010 4811123a7339f2d37449065f305c4094 105 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 49 94 - T 12-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 VAPA_1c01010 4811123a7339f2d37449065f305c4094 105 Pfam PF12833 Helix-turn-helix domain 17 99 3.8E-16 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 VAPA_1c01010 4811123a7339f2d37449065f305c4094 105 SUPERFAMILY SSF46689 49 100 8.51E-11 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 VAPA_1c01010 4811123a7339f2d37449065f305c4094 105 Gene3D G3DSA:1.10.10.60 2 104 7.2E-21 T 12-10-2018 VAPA_1c01010 4811123a7339f2d37449065f305c4094 105 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 82 98 3.0E-5 T 12-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 VAPA_1c01010 4811123a7339f2d37449065f305c4094 105 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 67 82 3.0E-5 T 12-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 VAPA_1c01010 4811123a7339f2d37449065f305c4094 105 SMART SM00342 11 98 1.3E-12 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 VAPA_1c01120 c968acd978e8f3480f022509beaff098 242 SUPERFAMILY SSF48498 101 226 6.23E-24 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily VAPA_1c01120 c968acd978e8f3480f022509beaff098 242 SUPERFAMILY SSF46689 22 95 1.23E-18 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 VAPA_1c01120 c968acd978e8f3480f022509beaff098 242 Pfam PF00440 Bacterial regulatory proteins, tetR family 31 77 1.0E-14 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 VAPA_1c01120 c968acd978e8f3480f022509beaff098 242 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 31 44 1.3E-6 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 VAPA_1c01120 c968acd978e8f3480f022509beaff098 242 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 52 75 1.3E-6 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 VAPA_1c01120 c968acd978e8f3480f022509beaff098 242 Gene3D G3DSA:1.10.357.10 29 227 2.1E-52 T 12-10-2018 VAPA_1c54500 9c6fa4d0312c6dd86221949d248c8051 227 Pfam PF07729 FCD domain 87 210 9.9E-14 T 12-10-2018 IPR011711 GntR, C-terminal VAPA_1c54500 9c6fa4d0312c6dd86221949d248c8051 227 SMART SM00895 87 211 2.3E-4 T 12-10-2018 IPR011711 GntR, C-terminal VAPA_1c54500 9c6fa4d0312c6dd86221949d248c8051 227 Gene3D G3DSA:1.10.10.10 3 79 5.9E-18 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c54500 9c6fa4d0312c6dd86221949d248c8051 227 SMART SM00345 19 77 1.8E-12 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_1c54500 9c6fa4d0312c6dd86221949d248c8051 227 Gene3D G3DSA:1.20.120.530 81 224 1.9E-14 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal VAPA_1c54500 9c6fa4d0312c6dd86221949d248c8051 227 Pfam PF00392 Bacterial regulatory proteins, gntR family 18 77 1.4E-14 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_1c54500 9c6fa4d0312c6dd86221949d248c8051 227 SUPERFAMILY SSF46785 10 81 1.36E-16 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c54500 9c6fa4d0312c6dd86221949d248c8051 227 SUPERFAMILY SSF48008 84 219 5.75E-17 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal VAPA_1c43970 5a0fce3db655b1b6a23db7f2ca207eb5 376 Pfam PF00196 Bacterial regulatory proteins, luxR family 309 362 9.5E-15 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_1c43970 5a0fce3db655b1b6a23db7f2ca207eb5 376 SUPERFAMILY SSF52172 27 159 1.85E-40 T 12-10-2018 IPR011006 CheY-like superfamily VAPA_1c43970 5a0fce3db655b1b6a23db7f2ca207eb5 376 SUPERFAMILY SSF46894 301 365 1.22E-16 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 VAPA_1c43970 5a0fce3db655b1b6a23db7f2ca207eb5 376 Gene3D G3DSA:1.10.10.10 306 373 1.1E-19 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c43970 5a0fce3db655b1b6a23db7f2ca207eb5 376 SMART SM00448 25 138 1.5E-37 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_1c43970 5a0fce3db655b1b6a23db7f2ca207eb5 376 Gene3D G3DSA:3.40.50.12740 25 220 1.0E-47 T 12-10-2018 VAPA_1c43970 5a0fce3db655b1b6a23db7f2ca207eb5 376 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 309 323 1.5E-9 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_1c43970 5a0fce3db655b1b6a23db7f2ca207eb5 376 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 339 351 1.5E-9 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_1c43970 5a0fce3db655b1b6a23db7f2ca207eb5 376 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 323 339 1.5E-9 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_1c43970 5a0fce3db655b1b6a23db7f2ca207eb5 376 SMART SM00421 306 363 2.0E-16 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_1c43970 5a0fce3db655b1b6a23db7f2ca207eb5 376 Pfam PF00072 Response regulator receiver domain 27 138 5.0E-28 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_1c04680 1d00f662933406732c12f7256d396efb 376 SMART SM01002 145 319 5.5E-82 T 12-10-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain VAPA_1c04680 1d00f662933406732c12f7256d396efb 376 SUPERFAMILY SSF52283 1 167 5.02E-51 T 12-10-2018 VAPA_1c04680 1d00f662933406732c12f7256d396efb 376 SUPERFAMILY SSF51735 136 324 2.11E-33 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c04680 1d00f662933406732c12f7256d396efb 376 Gene3D G3DSA:3.40.50.720 3 372 2.0E-140 T 12-10-2018 VAPA_1c04680 1d00f662933406732c12f7256d396efb 376 SMART SM01003 4 136 2.7E-65 T 12-10-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal VAPA_1c04680 1d00f662933406732c12f7256d396efb 376 Gene3D G3DSA:3.40.50.720 136 326 2.0E-140 T 12-10-2018 VAPA_1c04680 1d00f662933406732c12f7256d396efb 376 Pfam PF05222 Alanine dehydrogenase/PNT, N-terminal domain 4 136 4.9E-43 T 12-10-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal VAPA_1c04680 1d00f662933406732c12f7256d396efb 376 Pfam PF01262 Alanine dehydrogenase/PNT, C-terminal domain 140 375 6.2E-71 T 12-10-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain VAPA_1c52650 7e50cd0a5726b6ab9544d67a6ac090bd 126 SUPERFAMILY SSF158634 1 126 6.93E-46 T 12-10-2018 VAPA_1c52650 7e50cd0a5726b6ab9544d67a6ac090bd 126 Pfam PF12200 Domain of unknown function (DUF3597) 3 121 8.1E-46 T 12-10-2018 IPR022016 Domain of unknown function DUF3597 VAPA_1c13260 6e4ad387b8902c7396c22db92247cfae 553 Pfam PF02690 Na+/Pi-cotransporter 13 147 1.9E-33 T 12-10-2018 IPR003841 Sodium-dependent phosphate transport protein GO:0015321|GO:0016020|GO:0044341 Reactome: R-HSA-427589 VAPA_1c13260 6e4ad387b8902c7396c22db92247cfae 553 Pfam PF02690 Na+/Pi-cotransporter 139 279 7.8E-9 T 12-10-2018 IPR003841 Sodium-dependent phosphate transport protein GO:0015321|GO:0016020|GO:0044341 Reactome: R-HSA-427589 VAPA_1c13260 6e4ad387b8902c7396c22db92247cfae 553 Gene3D G3DSA:1.20.58.220 334 429 1.1E-9 T 12-10-2018 IPR038078 PhoU-like domain superfamily VAPA_1c13260 6e4ad387b8902c7396c22db92247cfae 553 TIGRFAM TIGR00704 NaPi_cotrn_rel: Na/Pi-cotransporter II-related protein 2 305 3.7E-75 T 12-10-2018 IPR004633 Na/Pi-cotransporter II-related/YqeW-like protein GO:0016020 VAPA_1c13260 6e4ad387b8902c7396c22db92247cfae 553 SUPERFAMILY SSF109755 320 532 6.17E-35 T 12-10-2018 VAPA_1c13260 6e4ad387b8902c7396c22db92247cfae 553 Gene3D G3DSA:1.20.58.220 441 535 1.3E-5 T 12-10-2018 IPR038078 PhoU-like domain superfamily VAPA_1c13260 6e4ad387b8902c7396c22db92247cfae 553 Pfam PF01895 PhoU domain 447 528 3.8E-6 T 12-10-2018 IPR026022 PhoU domain VAPA_1c13260 6e4ad387b8902c7396c22db92247cfae 553 Pfam PF01895 PhoU domain 343 422 9.8E-11 T 12-10-2018 IPR026022 PhoU domain VAPA_2c06030 31f95a163cee413c28d67547cce60782 351 Pfam PF00892 EamA-like transporter family 156 286 2.4E-8 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 VAPA_2c06030 31f95a163cee413c28d67547cce60782 351 Pfam PF00892 EamA-like transporter family 13 142 6.2E-17 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 VAPA_2c06030 31f95a163cee413c28d67547cce60782 351 SUPERFAMILY SSF103481 198 291 8.37E-6 T 12-10-2018 VAPA_2c06030 31f95a163cee413c28d67547cce60782 351 SUPERFAMILY SSF103481 47 149 1.83E-9 T 12-10-2018 VAPA_1c09460 878b3049aaf73f5baf0bb2dbaf176f45 271 PRINTS PR00069 Aldo-keto reductase signature 190 214 1.3E-46 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 VAPA_1c09460 878b3049aaf73f5baf0bb2dbaf176f45 271 PRINTS PR00069 Aldo-keto reductase signature 85 103 1.3E-46 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 VAPA_1c09460 878b3049aaf73f5baf0bb2dbaf176f45 271 PRINTS PR00069 Aldo-keto reductase signature 118 135 1.3E-46 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 VAPA_1c09460 878b3049aaf73f5baf0bb2dbaf176f45 271 PRINTS PR00069 Aldo-keto reductase signature 153 182 1.3E-46 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 VAPA_1c09460 878b3049aaf73f5baf0bb2dbaf176f45 271 PRINTS PR00069 Aldo-keto reductase signature 29 53 1.3E-46 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 VAPA_1c09460 878b3049aaf73f5baf0bb2dbaf176f45 271 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 118 135 - T 12-10-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 VAPA_1c09460 878b3049aaf73f5baf0bb2dbaf176f45 271 Gene3D G3DSA:3.20.20.100 1 271 1.7E-93 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily VAPA_1c09460 878b3049aaf73f5baf0bb2dbaf176f45 271 SUPERFAMILY SSF51430 3 262 1.44E-81 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily VAPA_1c09460 878b3049aaf73f5baf0bb2dbaf176f45 271 Pfam PF00248 Aldo/keto reductase family 12 254 1.3E-48 T 12-10-2018 IPR023210 NADP-dependent oxidoreductase domain VAPA_1c09460 878b3049aaf73f5baf0bb2dbaf176f45 271 PIRSF PIRSF000097 1 269 2.9E-70 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 VAPA_1c18090 8906f7abf52722251e0ca9d89fc0ef26 530 Gene3D G3DSA:3.90.1210.30 11 88 7.4E-24 T 12-10-2018 VAPA_1c18090 8906f7abf52722251e0ca9d89fc0ef26 530 Pfam PF04295 D-galactarate dehydratase / Altronate hydrolase, C terminus 116 528 2.8E-142 T 12-10-2018 IPR007392 D-galactarate/Altronate dehydratase, C-terminal GO:0016829 VAPA_1c18090 8906f7abf52722251e0ca9d89fc0ef26 530 Pfam PF08666 SAF domain 19 86 5.7E-12 T 12-10-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 VAPA_1c18090 8906f7abf52722251e0ca9d89fc0ef26 530 SMART SM00858 19 89 1.1E-12 T 12-10-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 VAPA_1c18090 8906f7abf52722251e0ca9d89fc0ef26 530 TIGRFAM TIGR03248 galactar-dH20: galactarate dehydratase 11 530 1.0E-276 T 12-10-2018 IPR017654 Galactarate dehydratase GarD-like GO:0008867|GO:0046392 KEGG: 00053+4.2.1.42|MetaCyc: PWY-6497 VAPA_1c42450 cf2f531d21d4ba841e681466d0bb5b6b 68 Pfam PF11943 Protein of unknown function (DUF3460) 8 65 3.6E-28 T 12-10-2018 IPR021853 Protein of unknown function DUF3460 VAPA_1c47680 3d5c1337c6b1dda66f3491c261e0812b 321 SUPERFAMILY SSF53613 34 294 6.55E-43 T 12-10-2018 IPR029056 Ribokinase-like VAPA_1c47680 3d5c1337c6b1dda66f3491c261e0812b 321 Gene3D G3DSA:3.40.1190.20 17 295 6.0E-42 T 12-10-2018 IPR029056 Ribokinase-like VAPA_1c47680 3d5c1337c6b1dda66f3491c261e0812b 321 Pfam PF08543 Phosphomethylpyrimidine kinase 44 285 1.5E-32 T 12-10-2018 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-6798695|Reactome: R-HSA-964975 VAPA_1c35870 b8c136d57d4612c4f57d9cc2b4143a3e 358 Gene3D G3DSA:3.40.50.1100 59 165 4.3E-68 T 12-10-2018 VAPA_1c35870 b8c136d57d4612c4f57d9cc2b4143a3e 358 SUPERFAMILY SSF53686 29 340 1.27E-69 T 12-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme VAPA_1c35870 b8c136d57d4612c4f57d9cc2b4143a3e 358 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 37 319 9.5E-50 T 12-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme VAPA_1c35870 b8c136d57d4612c4f57d9cc2b4143a3e 358 Gene3D G3DSA:3.40.50.1100 43 329 4.3E-68 T 12-10-2018 VAPA_1c41220 43c1f96d37639a0960ca3b8d80a91655 309 Pfam PF00892 EamA-like transporter family 21 152 8.0E-13 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 VAPA_1c41220 43c1f96d37639a0960ca3b8d80a91655 309 Pfam PF00892 EamA-like transporter family 167 302 1.3E-16 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 VAPA_1c41220 43c1f96d37639a0960ca3b8d80a91655 309 SUPERFAMILY SSF103481 230 305 1.23E-12 T 12-10-2018 VAPA_1c41220 43c1f96d37639a0960ca3b8d80a91655 309 SUPERFAMILY SSF103481 55 152 4.97E-12 T 12-10-2018 VAPA_2c06670 161251082a19bd9a6c6bf321f62c5c9d 508 Gene3D G3DSA:3.40.50.300 265 507 4.6E-42 T 12-10-2018 VAPA_2c06670 161251082a19bd9a6c6bf321f62c5c9d 508 Gene3D G3DSA:3.40.50.300 1 248 8.9E-54 T 12-10-2018 VAPA_2c06670 161251082a19bd9a6c6bf321f62c5c9d 508 SMART SM00382 29 219 2.8E-12 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_2c06670 161251082a19bd9a6c6bf321f62c5c9d 508 SMART SM00382 280 475 6.2E-4 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_2c06670 161251082a19bd9a6c6bf321f62c5c9d 508 SUPERFAMILY SSF52540 3 228 4.26E-55 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_2c06670 161251082a19bd9a6c6bf321f62c5c9d 508 ProSitePatterns PS00211 ABC transporters family signature. 399 413 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_2c06670 161251082a19bd9a6c6bf321f62c5c9d 508 Pfam PF00005 ABC transporter 20 171 4.8E-27 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_2c06670 161251082a19bd9a6c6bf321f62c5c9d 508 Pfam PF00005 ABC transporter 272 426 9.3E-17 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_2c06670 161251082a19bd9a6c6bf321f62c5c9d 508 SUPERFAMILY SSF52540 271 479 6.94E-44 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c01410 feb42a4af6c0a0aceb370256b152e5a9 343 Pfam PF13377 Periplasmic binding protein-like domain 177 337 8.8E-39 T 12-10-2018 VAPA_1c01410 feb42a4af6c0a0aceb370256b152e5a9 343 Gene3D G3DSA:1.10.260.40 2 68 2.1E-20 T 12-10-2018 VAPA_1c01410 feb42a4af6c0a0aceb370256b152e5a9 343 Pfam PF00356 Bacterial regulatory proteins, lacI family 11 58 3.7E-12 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 VAPA_1c01410 feb42a4af6c0a0aceb370256b152e5a9 343 Gene3D G3DSA:3.40.50.2300 162 339 3.9E-58 T 12-10-2018 VAPA_1c01410 feb42a4af6c0a0aceb370256b152e5a9 343 Gene3D G3DSA:3.40.50.2300 69 158 1.9E-19 T 12-10-2018 VAPA_1c01410 feb42a4af6c0a0aceb370256b152e5a9 343 SUPERFAMILY SSF47413 9 69 1.88E-14 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 VAPA_1c01410 feb42a4af6c0a0aceb370256b152e5a9 343 SUPERFAMILY SSF53822 71 340 8.25E-74 T 12-10-2018 IPR028082 Periplasmic binding protein-like I VAPA_1c01410 feb42a4af6c0a0aceb370256b152e5a9 343 SMART SM00354 9 81 3.3E-26 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 VAPA_1c38490 1d7d706459997271f3ec846eeb4a75a9 458 SUPERFAMILY SSF53756 63 431 1.1E-11 T 12-10-2018 VAPA_1c38490 1d7d706459997271f3ec846eeb4a75a9 458 Gene3D G3DSA:3.40.50.11720 35 211 2.3E-42 T 12-10-2018 IPR038107 3-deoxy-D-manno-octulosonic-acid transferase, N-terminal domain superfamily KEGG: 00540+2.4.99.12|MetaCyc: PWY-7675 VAPA_1c38490 1d7d706459997271f3ec846eeb4a75a9 458 Gene3D G3DSA:3.40.50.2000 217 417 2.9E-63 T 12-10-2018 VAPA_1c38490 1d7d706459997271f3ec846eeb4a75a9 458 Pfam PF00534 Glycosyl transferases group 1 313 413 2.8E-6 T 12-10-2018 IPR001296 Glycosyl transferase, family 1 VAPA_1c38490 1d7d706459997271f3ec846eeb4a75a9 458 Pfam PF04413 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) 38 212 2.1E-56 T 12-10-2018 IPR007507 3-deoxy-D-manno-octulosonic-acid transferase, N-terminal KEGG: 00540+2.4.99.12|MetaCyc: PWY-7675 VAPA_1c04310 81881dcae305ff5abb2d48397c75442c 258 Gene3D G3DSA:3.40.50.300 2 249 1.7E-61 T 12-10-2018 VAPA_1c04310 81881dcae305ff5abb2d48397c75442c 258 SUPERFAMILY SSF52540 6 249 2.98E-62 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c04310 81881dcae305ff5abb2d48397c75442c 258 SMART SM00382 31 234 4.0E-10 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c04310 81881dcae305ff5abb2d48397c75442c 258 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 226 248 9.3E-11 T 12-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal VAPA_1c04310 81881dcae305ff5abb2d48397c75442c 258 Pfam PF00005 ABC transporter 23 176 2.9E-28 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c43630 b31612f7643cba05d3e398d5765f54bb 370 Gene3D G3DSA:3.30.70.1660 112 350 1.9E-92 T 12-10-2018 VAPA_1c43630 b31612f7643cba05d3e398d5765f54bb 370 Pfam PF03462 PCRF domain 14 211 7.9E-70 T 12-10-2018 IPR005139 Peptide chain release factor GO:0006415 VAPA_1c43630 b31612f7643cba05d3e398d5765f54bb 370 Pfam PF00472 RF-1 domain 221 329 3.2E-40 T 12-10-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 VAPA_1c43630 b31612f7643cba05d3e398d5765f54bb 370 Gene3D G3DSA:1.20.58.410 6 102 3.8E-5 T 12-10-2018 VAPA_1c43630 b31612f7643cba05d3e398d5765f54bb 370 TIGRFAM TIGR00019 prfA: peptide chain release factor 1 4 365 1.0E-151 T 12-10-2018 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 VAPA_1c43630 b31612f7643cba05d3e398d5765f54bb 370 SUPERFAMILY SSF75620 14 361 7.06E-130 T 12-10-2018 VAPA_1c43630 b31612f7643cba05d3e398d5765f54bb 370 Gene3D G3DSA:3.30.160.20 218 305 1.9E-92 T 12-10-2018 VAPA_1c43630 b31612f7643cba05d3e398d5765f54bb 370 Hamap MF_00093 Peptide chain release factor 1 [prfA]. 5 365 39.621 T 12-10-2018 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 VAPA_1c43630 b31612f7643cba05d3e398d5765f54bb 370 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 236 252 - T 12-10-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 VAPA_1c43630 b31612f7643cba05d3e398d5765f54bb 370 SMART SM00937 63 186 4.0E-66 T 12-10-2018 IPR005139 Peptide chain release factor GO:0006415 VAPA_2c09250 6b8c0586b49466d818a19154322a98d8 543 Gene3D G3DSA:1.10.246.130 251 361 1.4E-27 T 12-10-2018 VAPA_2c09250 6b8c0586b49466d818a19154322a98d8 543 TIGRFAM TIGR00066 g_glut_trans: gamma-glutamyltransferase 6 528 7.9E-114 T 12-10-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-4061|MetaCyc: PWY-5826|MetaCyc: PWY-6842|MetaCyc: PWY-7112|MetaCyc: PWY-7559 VAPA_2c09250 6b8c0586b49466d818a19154322a98d8 543 SUPERFAMILY SSF56235 3 528 6.95E-145 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal VAPA_2c09250 6b8c0586b49466d818a19154322a98d8 543 Gene3D G3DSA:3.60.20.40 362 535 5.6E-47 T 12-10-2018 VAPA_2c09250 6b8c0586b49466d818a19154322a98d8 543 Pfam PF01019 Gamma-glutamyltranspeptidase 20 532 3.4E-125 T 12-10-2018 VAPA_2c09250 6b8c0586b49466d818a19154322a98d8 543 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 438 455 8.9E-59 T 12-10-2018 VAPA_2c09250 6b8c0586b49466d818a19154322a98d8 543 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 128 147 8.9E-59 T 12-10-2018 VAPA_2c09250 6b8c0586b49466d818a19154322a98d8 543 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 264 283 8.9E-59 T 12-10-2018 VAPA_2c09250 6b8c0586b49466d818a19154322a98d8 543 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 383 401 8.9E-59 T 12-10-2018 VAPA_2c09250 6b8c0586b49466d818a19154322a98d8 543 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 361 379 8.9E-59 T 12-10-2018 VAPA_2c09250 6b8c0586b49466d818a19154322a98d8 543 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 414 429 8.9E-59 T 12-10-2018 VAPA_2c09250 6b8c0586b49466d818a19154322a98d8 543 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 27 52 8.9E-59 T 12-10-2018 VAPA_2c09250 6b8c0586b49466d818a19154322a98d8 543 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 235 251 8.9E-59 T 12-10-2018 VAPA_2c09250 6b8c0586b49466d818a19154322a98d8 543 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 110 128 8.9E-59 T 12-10-2018 VAPA_1c24740 ad6c6f5376d59897d486375c8e56e4f4 271 SMART SM00382 37 217 4.7E-14 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c24740 ad6c6f5376d59897d486375c8e56e4f4 271 Gene3D G3DSA:3.40.50.300 5 248 1.5E-61 T 12-10-2018 VAPA_1c24740 ad6c6f5376d59897d486375c8e56e4f4 271 SUPERFAMILY SSF52540 27 232 1.86E-62 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c24740 ad6c6f5376d59897d486375c8e56e4f4 271 Pfam PF00005 ABC transporter 30 167 2.7E-27 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c24740 ad6c6f5376d59897d486375c8e56e4f4 271 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_2c05330 e9c370e430237efd5a649a10cdce32d6 516 SUPERFAMILY SSF143243 23 174 1.31E-21 T 12-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VAPA_2c05330 e9c370e430237efd5a649a10cdce32d6 516 Gene3D G3DSA:1.10.645.20 161 515 6.1E-102 T 12-10-2018 IPR038290 NADH-quinone oxidoreductase, subunit D superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VAPA_2c05330 e9c370e430237efd5a649a10cdce32d6 516 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 284 441 9.0E-30 T 12-10-2018 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VAPA_2c05330 e9c370e430237efd5a649a10cdce32d6 516 SUPERFAMILY SSF56762 170 515 1.44E-98 T 12-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VAPA_2c05330 e9c370e430237efd5a649a10cdce32d6 516 Pfam PF00329 Respiratory-chain NADH dehydrogenase, 30 Kd subunit 24 126 1.8E-9 T 12-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VAPA_1c45640 6d2fb0dcab2fb8c66f25f9d7f1c8a3bd 543 Gene3D G3DSA:1.20.210.10 16 541 1.3E-218 T 12-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 VAPA_1c45640 6d2fb0dcab2fb8c66f25f9d7f1c8a3bd 543 TIGRFAM TIGR02891 CtaD_CoxA: cytochrome c oxidase, subunit I 30 533 7.8E-212 T 12-10-2018 IPR014241 Cytochrome c oxidase, subunit I bacterial type GO:0004129|GO:0005886|GO:0015990|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 VAPA_1c45640 6d2fb0dcab2fb8c66f25f9d7f1c8a3bd 543 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 38 479 1.3E-150 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 VAPA_1c45640 6d2fb0dcab2fb8c66f25f9d7f1c8a3bd 543 SUPERFAMILY SSF81442 26 534 3.79E-194 T 12-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 VAPA_1c45640 6d2fb0dcab2fb8c66f25f9d7f1c8a3bd 543 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 257 311 - T 12-10-2018 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 VAPA_1c45640 6d2fb0dcab2fb8c66f25f9d7f1c8a3bd 543 PRINTS PR01165 Cytochrome c oxidase subunit I signature 388 407 2.6E-120 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 VAPA_1c45640 6d2fb0dcab2fb8c66f25f9d7f1c8a3bd 543 PRINTS PR01165 Cytochrome c oxidase subunit I signature 146 158 2.6E-120 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 VAPA_1c45640 6d2fb0dcab2fb8c66f25f9d7f1c8a3bd 543 PRINTS PR01165 Cytochrome c oxidase subunit I signature 301 316 2.6E-120 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 VAPA_1c45640 6d2fb0dcab2fb8c66f25f9d7f1c8a3bd 543 PRINTS PR01165 Cytochrome c oxidase subunit I signature 175 193 2.6E-120 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 VAPA_1c45640 6d2fb0dcab2fb8c66f25f9d7f1c8a3bd 543 PRINTS PR01165 Cytochrome c oxidase subunit I signature 204 223 2.6E-120 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 VAPA_1c45640 6d2fb0dcab2fb8c66f25f9d7f1c8a3bd 543 PRINTS PR01165 Cytochrome c oxidase subunit I signature 360 378 2.6E-120 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 VAPA_1c45640 6d2fb0dcab2fb8c66f25f9d7f1c8a3bd 543 PRINTS PR01165 Cytochrome c oxidase subunit I signature 438 459 2.6E-120 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 VAPA_1c45640 6d2fb0dcab2fb8c66f25f9d7f1c8a3bd 543 PRINTS PR01165 Cytochrome c oxidase subunit I signature 76 99 2.6E-120 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 VAPA_1c45640 6d2fb0dcab2fb8c66f25f9d7f1c8a3bd 543 PRINTS PR01165 Cytochrome c oxidase subunit I signature 103 127 2.6E-120 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 VAPA_1c45640 6d2fb0dcab2fb8c66f25f9d7f1c8a3bd 543 PRINTS PR01165 Cytochrome c oxidase subunit I signature 325 346 2.6E-120 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 VAPA_1c45640 6d2fb0dcab2fb8c66f25f9d7f1c8a3bd 543 PRINTS PR01165 Cytochrome c oxidase subunit I signature 29 54 2.6E-120 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 VAPA_1c45640 6d2fb0dcab2fb8c66f25f9d7f1c8a3bd 543 PRINTS PR01165 Cytochrome c oxidase subunit I signature 255 276 2.6E-120 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 VAPA_1c45830 9886102f543d235ec338fc2240f85293 175 SUPERFAMILY SSF55961 20 174 7.27E-24 T 12-10-2018 VAPA_1c45830 9886102f543d235ec338fc2240f85293 175 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 27 174 1.1E-21 T 12-10-2018 IPR019587 Polyketide cyclase/dehydrase VAPA_1c45830 9886102f543d235ec338fc2240f85293 175 Gene3D G3DSA:3.30.530.20 24 175 7.9E-25 T 12-10-2018 IPR023393 START-like domain superfamily VAPA_1c31410 f2ca733028592b44957396dafffda1e1 681 SMART SM00382 371 515 5.0E-9 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c31410 f2ca733028592b44957396dafffda1e1 681 Gene3D G3DSA:3.30.450.40 22 207 4.6E-51 T 12-10-2018 IPR029016 GAF-like domain superfamily VAPA_1c31410 f2ca733028592b44957396dafffda1e1 681 Pfam PF01590 GAF domain 79 205 1.6E-6 T 12-10-2018 IPR003018 GAF domain GO:0005515 VAPA_1c31410 f2ca733028592b44957396dafffda1e1 681 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 375 388 - T 12-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 VAPA_1c31410 f2ca733028592b44957396dafffda1e1 681 Gene3D G3DSA:1.10.10.60 627 678 4.4E-13 T 12-10-2018 VAPA_1c31410 f2ca733028592b44957396dafffda1e1 681 Gene3D G3DSA:3.40.50.300 346 523 7.8E-60 T 12-10-2018 VAPA_1c31410 f2ca733028592b44957396dafffda1e1 681 Pfam PF02954 Bacterial regulatory protein, Fis family 637 672 1.9E-11 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 VAPA_1c31410 f2ca733028592b44957396dafffda1e1 681 SUPERFAMILY SSF52540 360 589 1.18E-61 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c31410 f2ca733028592b44957396dafffda1e1 681 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 560 569 - T 12-10-2018 IPR025944 Sigma-54 interaction domain, conserved site VAPA_1c31410 f2ca733028592b44957396dafffda1e1 681 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 656 676 1.0E-6 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 VAPA_1c31410 f2ca733028592b44957396dafffda1e1 681 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 639 656 1.0E-6 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 VAPA_1c31410 f2ca733028592b44957396dafffda1e1 681 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 438 453 - T 12-10-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 VAPA_1c31410 f2ca733028592b44957396dafffda1e1 681 Pfam PF00158 Sigma-54 interaction domain 356 518 7.7E-62 T 12-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 VAPA_1c31410 f2ca733028592b44957396dafffda1e1 681 SUPERFAMILY SSF46689 629 675 1.0E-10 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 VAPA_1c31410 f2ca733028592b44957396dafffda1e1 681 Gene3D G3DSA:1.10.8.60 524 596 2.3E-12 T 12-10-2018 VAPA_1c31410 f2ca733028592b44957396dafffda1e1 681 SUPERFAMILY SSF55781 66 206 2.55E-11 T 12-10-2018 VAPA_1c46610 f72f533485e247ce0a5fe34baca3b592 109 Gene3D G3DSA:1.10.150.240 11 92 4.3E-14 T 12-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 VAPA_1c23690 c160d8b9be6c2b0cd8bd106ddadaa8eb 230 Gene3D G3DSA:1.25.40.10 39 195 1.5E-6 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 VAPA_1c23690 c160d8b9be6c2b0cd8bd106ddadaa8eb 230 Pfam PF09976 Tetratricopeptide repeat-like domain 17 208 2.3E-58 T 12-10-2018 IPR018704 Tetratricopeptide repeat-like domain Reactome: R-HSA-192823|Reactome: R-HSA-381038|Reactome: R-HSA-381426|Reactome: R-HSA-6798695|Reactome: R-HSA-8957275 VAPA_1c23690 c160d8b9be6c2b0cd8bd106ddadaa8eb 230 PIRSF PIRSF006170 3 215 6.2E-60 T 12-10-2018 IPR026039 Uncharacterised protein family UPF0070 VAPA_1c12350 c539f411c41db0aadb802954fafa27ca 129 Hamap MF_01021 Phosphoribosyl-AMP cyclohydrolase [hisI]. 3 110 31.737 T 12-10-2018 IPR026660 Phosphoribosyl-AMP cyclohydrolase GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 VAPA_1c12350 c539f411c41db0aadb802954fafa27ca 129 SUPERFAMILY SSF141734 2 123 2.62E-48 T 12-10-2018 IPR038019 Phosphoribosyl-AMP cyclohydrolase domain superfamily KEGG: 00340+3.5.4.19 VAPA_1c12350 c539f411c41db0aadb802954fafa27ca 129 Pfam PF01502 Phosphoribosyl-AMP cyclohydrolase 29 106 8.1E-34 T 12-10-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 VAPA_1c12350 c539f411c41db0aadb802954fafa27ca 129 ProDom PD002610 PHOSPHORIBOSYL-AMP BIOSYNTHESIS CYCLOHYDROLASE HYDROLASE HISTIDINE AMINO-ACID PRA-CH PHOSPHORIBOSYL-ATP BIFUNCTIONAL INCLUDES: 52 106 1.0E-25 T 12-10-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 VAPA_1c12350 c539f411c41db0aadb802954fafa27ca 129 Gene3D G3DSA:3.10.20.400 1 97 4.8E-37 T 12-10-2018 IPR038019 Phosphoribosyl-AMP cyclohydrolase domain superfamily KEGG: 00340+3.5.4.19 VAPA_2c11140 f4e1057b4320428145d3b89b30d41fa8 237 SUPERFAMILY SSF52172 21 149 9.53E-21 T 12-10-2018 IPR011006 CheY-like superfamily VAPA_2c11140 f4e1057b4320428145d3b89b30d41fa8 237 SMART SM00421 179 236 5.2E-17 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_2c11140 f4e1057b4320428145d3b89b30d41fa8 237 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 212 224 1.7E-7 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_2c11140 f4e1057b4320428145d3b89b30d41fa8 237 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 182 196 1.7E-7 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_2c11140 f4e1057b4320428145d3b89b30d41fa8 237 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 196 212 1.7E-7 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_2c11140 f4e1057b4320428145d3b89b30d41fa8 237 Gene3D G3DSA:3.40.50.2300 22 151 9.0E-22 T 12-10-2018 VAPA_2c11140 f4e1057b4320428145d3b89b30d41fa8 237 Pfam PF00072 Response regulator receiver domain 24 145 1.5E-15 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_2c11140 f4e1057b4320428145d3b89b30d41fa8 237 Gene3D G3DSA:1.10.10.10 161 236 3.1E-16 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_2c11140 f4e1057b4320428145d3b89b30d41fa8 237 SUPERFAMILY SSF46894 170 234 2.45E-15 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 VAPA_2c11140 f4e1057b4320428145d3b89b30d41fa8 237 Pfam PF00196 Bacterial regulatory proteins, luxR family 181 234 4.0E-15 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_2c11140 f4e1057b4320428145d3b89b30d41fa8 237 SMART SM00448 22 146 7.5E-13 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_2c02800 9a86ed0b2c87cf4b86ead477dc842986 111 SUPERFAMILY SSF81343 4 105 2.83E-14 T 12-10-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 VAPA_2c02800 9a86ed0b2c87cf4b86ead477dc842986 111 Gene3D G3DSA:1.20.1300.10 1 109 3.1E-14 T 12-10-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 VAPA_2c02800 9a86ed0b2c87cf4b86ead477dc842986 111 Pfam PF01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 5 97 1.4E-6 T 12-10-2018 IPR000701 Succinate dehydrogenase/fumarate reductase type B, transmembrane subunit GO:0016627 Reactome: R-HSA-611105|Reactome: R-HSA-71403 VAPA_2c09850 ed0755f33fc199e787b64421633f9fda 390 Gene3D G3DSA:1.20.58.710 138 238 1.3E-89 T 12-10-2018 VAPA_2c09850 ed0755f33fc199e787b64421633f9fda 390 Gene3D G3DSA:3.40.710.10 88 367 1.3E-89 T 12-10-2018 VAPA_2c09850 ed0755f33fc199e787b64421633f9fda 390 SUPERFAMILY SSF56601 29 377 4.74E-79 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like VAPA_2c09850 ed0755f33fc199e787b64421633f9fda 390 Pfam PF00144 Beta-lactamase 91 370 5.3E-33 T 12-10-2018 IPR001466 Beta-lactamase-related VAPA_1c51170 c5091295829017c0fcc0064ffb95d676 387 SUPERFAMILY SSF53822 30 383 2.46E-83 T 12-10-2018 IPR028082 Periplasmic binding protein-like I VAPA_1c51170 c5091295829017c0fcc0064ffb95d676 387 Pfam PF13458 Periplasmic binding protein 30 377 2.3E-72 T 12-10-2018 IPR028081 Leucine-binding protein domain VAPA_1c51170 c5091295829017c0fcc0064ffb95d676 387 Gene3D G3DSA:3.40.50.2300 150 279 1.5E-79 T 12-10-2018 VAPA_1c51170 c5091295829017c0fcc0064ffb95d676 387 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 53 69 1.8E-9 T 12-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 VAPA_1c51170 c5091295829017c0fcc0064ffb95d676 387 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 31 47 1.8E-9 T 12-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 VAPA_1c51170 c5091295829017c0fcc0064ffb95d676 387 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 260 278 1.8E-9 T 12-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 VAPA_1c51170 c5091295829017c0fcc0064ffb95d676 387 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 72 90 1.8E-9 T 12-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 VAPA_1c51170 c5091295829017c0fcc0064ffb95d676 387 Gene3D G3DSA:3.40.50.2300 39 344 1.5E-79 T 12-10-2018 VAPA_1c25540 31f7c87d943f11914ff8ece2ca295fc2 306 SUPERFAMILY SSF161098 93 288 8.94E-21 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c25540 31f7c87d943f11914ff8ece2ca295fc2 306 Gene3D G3DSA:1.10.3720.10 89 299 8.2E-26 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c25540 31f7c87d943f11914ff8ece2ca295fc2 306 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 304 1.1E-43 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 VAPA_1c44950 2e11f5c89ec0937d245f5dc929c5843e 304 Pfam PF08340 Domain of unknown function (DUF1732) 221 304 1.7E-34 T 12-10-2018 IPR013551 Domain of unknown function DUF1732 VAPA_1c44950 2e11f5c89ec0937d245f5dc929c5843e 304 TIGRFAM TIGR00255 TIGR00255: TIGR00255 family protein 30 304 3.4E-65 T 12-10-2018 IPR005229 Conserved hypothetical protein CHP00255 VAPA_1c44950 2e11f5c89ec0937d245f5dc929c5843e 304 Pfam PF03755 YicC-like family, N-terminal region 3 163 1.2E-33 T 12-10-2018 IPR013527 YicC-like, N-terminal VAPA_1c29200 40986bfc1de3b1b79ba437321611cdfd 506 Gene3D G3DSA:3.40.50.720 1 190 3.4E-63 T 12-10-2018 VAPA_1c29200 40986bfc1de3b1b79ba437321611cdfd 506 Gene3D G3DSA:1.10.1040.50 191 494 5.9E-87 T 12-10-2018 VAPA_1c29200 40986bfc1de3b1b79ba437321611cdfd 506 SUPERFAMILY SSF48179 187 293 3.23E-27 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 VAPA_1c29200 40986bfc1de3b1b79ba437321611cdfd 506 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 8 186 1.4E-59 T 12-10-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 VAPA_1c29200 40986bfc1de3b1b79ba437321611cdfd 506 SUPERFAMILY SSF48179 415 494 7.23E-16 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 VAPA_1c29200 40986bfc1de3b1b79ba437321611cdfd 506 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 188 285 1.3E-25 T 12-10-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 VAPA_1c29200 40986bfc1de3b1b79ba437321611cdfd 506 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 415 493 3.3E-15 T 12-10-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 VAPA_1c29200 40986bfc1de3b1b79ba437321611cdfd 506 Gene3D G3DSA:3.30.750.190 294 412 5.9E-87 T 12-10-2018 VAPA_1c29200 40986bfc1de3b1b79ba437321611cdfd 506 SUPERFAMILY SSF51735 5 187 1.25E-50 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c02860 6798e72bc88dfd15db7271b691096333 434 SUPERFAMILY SSF103473 3 410 4.05E-24 T 12-10-2018 IPR036259 MFS transporter superfamily VAPA_1c02860 6798e72bc88dfd15db7271b691096333 434 Pfam PF07690 Major Facilitator Superfamily 9 350 2.7E-15 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 VAPA_1c02860 6798e72bc88dfd15db7271b691096333 434 Gene3D G3DSA:1.20.1250.20 1 408 1.9E-22 T 12-10-2018 VAPA_2c07270 bb7e94e7f98accde2b635d1dd441595c 244 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_2c07270 bb7e94e7f98accde2b635d1dd441595c 244 Gene3D G3DSA:3.40.50.300 1 243 8.7E-79 T 12-10-2018 VAPA_2c07270 bb7e94e7f98accde2b635d1dd441595c 244 Pfam PF00005 ABC transporter 17 167 8.7E-35 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_2c07270 bb7e94e7f98accde2b635d1dd441595c 244 SUPERFAMILY SSF52540 1 237 1.27E-80 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_2c07270 bb7e94e7f98accde2b635d1dd441595c 244 PIRSF PIRSF039085 1 243 2.8E-107 T 12-10-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 VAPA_2c07270 bb7e94e7f98accde2b635d1dd441595c 244 SMART SM00382 26 215 1.9E-16 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c08670 d17bddbedf255dfae7606a6abe5270eb 287 Gene3D G3DSA:3.20.20.60 3 286 7.9E-100 T 12-10-2018 VAPA_1c08670 d17bddbedf255dfae7606a6abe5270eb 287 ProSitePatterns PS00161 Isocitrate lyase signature. 116 121 - T 12-10-2018 IPR018523 Isocitrate lyase/phosphorylmutase, conserved site GO:0003824 VAPA_1c08670 d17bddbedf255dfae7606a6abe5270eb 287 Pfam PF13714 Phosphoenolpyruvate phosphomutase 8 245 1.3E-48 T 12-10-2018 VAPA_1c08670 d17bddbedf255dfae7606a6abe5270eb 287 SUPERFAMILY SSF51621 5 286 4.26E-91 T 12-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 VAPA_1c24690 108105dad29ae35d9c2777aaa904e190 618 Gene3D G3DSA:3.40.50.300 13 182 5.6E-97 T 12-10-2018 VAPA_1c24690 108105dad29ae35d9c2777aaa904e190 618 TIGRFAM TIGR02397 dnaX_nterm: DNA polymerase III, subunit gamma and tau 3 364 2.6E-120 T 12-10-2018 IPR012763 DNA polymerase III, subunit gamma/ tau GO:0003887|GO:0005524|GO:0006260|GO:0009360 VAPA_1c24690 108105dad29ae35d9c2777aaa904e190 618 Gene3D G3DSA:1.20.272.10 247 370 2.9E-31 T 12-10-2018 VAPA_1c24690 108105dad29ae35d9c2777aaa904e190 618 Gene3D G3DSA:1.10.8.60 8 245 5.6E-97 T 12-10-2018 VAPA_1c24690 108105dad29ae35d9c2777aaa904e190 618 Pfam PF12169 DNA polymerase III subunits gamma and tau domain III 240 370 2.8E-24 T 12-10-2018 IPR022754 DNA polymerase III, gamma subunit, domain III GO:0003887 VAPA_1c24690 108105dad29ae35d9c2777aaa904e190 618 Pfam PF12170 DNA polymerase III tau subunit V interacting with alpha 495 610 5.9E-13 T 12-10-2018 IPR021029 DNA polymerase III, tau subunit, domain V GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 VAPA_1c24690 108105dad29ae35d9c2777aaa904e190 618 SUPERFAMILY SSF52540 33 227 1.04E-53 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c24690 108105dad29ae35d9c2777aaa904e190 618 SMART SM00382 37 184 5.9E-5 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c24690 108105dad29ae35d9c2777aaa904e190 618 Pfam PF13177 DNA polymerase III, delta subunit 20 183 5.1E-40 T 12-10-2018 VAPA_1c24690 108105dad29ae35d9c2777aaa904e190 618 Gene3D G3DSA:3.30.300.150 489 600 2.8E-8 T 12-10-2018 IPR038249 DNA polymerase III, tau subunit, C-terminal domain superfamily KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 VAPA_1c24690 108105dad29ae35d9c2777aaa904e190 618 SUPERFAMILY SSF48019 249 372 6.46E-24 T 12-10-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 VAPA_2c13260 e2642e7afa7dcf1aaf929cfb242115ad 240 PIRSF PIRSF003299 1 228 9.5E-46 T 12-10-2018 IPR026264 Type IV secretion system protein VirB8/PtlE GO:0030255 VAPA_2c13260 e2642e7afa7dcf1aaf929cfb242115ad 240 Pfam PF04335 VirB8 protein 14 226 6.1E-47 T 12-10-2018 IPR007430 Bacterial virulence protein VirB8 GO:0016020 VAPA_2c13260 e2642e7afa7dcf1aaf929cfb242115ad 240 Gene3D G3DSA:3.10.450.230 82 231 3.5E-40 T 12-10-2018 VAPA_2c13260 e2642e7afa7dcf1aaf929cfb242115ad 240 SUPERFAMILY SSF54427 85 227 7.01E-34 T 12-10-2018 IPR032710 NTF2-like domain superfamily VAPA_1c42540 d7b28e23bf5780175eddc6502c9a1a8c 344 ProSitePatterns PS00957 NAD-dependent glycerol-3-phosphate dehydrogenase signature. 189 210 - T 12-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 VAPA_1c42540 d7b28e23bf5780175eddc6502c9a1a8c 344 Gene3D G3DSA:3.40.50.720 1 188 4.9E-47 T 12-10-2018 VAPA_1c42540 d7b28e23bf5780175eddc6502c9a1a8c 344 SUPERFAMILY SSF51735 1 181 3.07E-39 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c42540 d7b28e23bf5780175eddc6502c9a1a8c 344 Gene3D G3DSA:1.10.1040.10 190 336 3.4E-46 T 12-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 VAPA_1c42540 d7b28e23bf5780175eddc6502c9a1a8c 344 Hamap MF_00394 Glycerol-3-phosphate dehydrogenase [NAD(P)+] [gpsA]. 1 323 34.489 T 12-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 VAPA_1c42540 d7b28e23bf5780175eddc6502c9a1a8c 344 Pfam PF07479 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus 181 321 4.1E-47 T 12-10-2018 IPR006109 Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal GO:0004367|GO:0005975|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 VAPA_1c42540 d7b28e23bf5780175eddc6502c9a1a8c 344 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 5 22 4.3E-39 T 12-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 VAPA_1c42540 d7b28e23bf5780175eddc6502c9a1a8c 344 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 199 223 4.3E-39 T 12-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 VAPA_1c42540 d7b28e23bf5780175eddc6502c9a1a8c 344 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 174 198 4.3E-39 T 12-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 VAPA_1c42540 d7b28e23bf5780175eddc6502c9a1a8c 344 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 239 256 4.3E-39 T 12-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 VAPA_1c42540 d7b28e23bf5780175eddc6502c9a1a8c 344 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 55 82 4.3E-39 T 12-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 VAPA_1c42540 d7b28e23bf5780175eddc6502c9a1a8c 344 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 134 154 4.3E-39 T 12-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 VAPA_1c42540 d7b28e23bf5780175eddc6502c9a1a8c 344 SUPERFAMILY SSF48179 180 332 8.33E-52 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 VAPA_1c42540 d7b28e23bf5780175eddc6502c9a1a8c 344 Pfam PF01210 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 2 159 9.8E-35 T 12-10-2018 IPR011128 Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal GO:0016616|GO:0046168|GO:0051287|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 VAPA_1c42540 d7b28e23bf5780175eddc6502c9a1a8c 344 PIRSF PIRSF000114 1 333 5.1E-88 T 12-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 VAPA_1c09050 cd8207650260c70416c9d0a6e954e433 711 Pfam PF00378 Enoyl-CoA hydratase/isomerase 22 213 5.0E-36 T 12-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 VAPA_1c09050 cd8207650260c70416c9d0a6e954e433 711 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 308 483 1.2E-56 T 12-10-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 VAPA_1c09050 cd8207650260c70416c9d0a6e954e433 711 SUPERFAMILY SSF48179 487 630 6.72E-28 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 VAPA_1c09050 cd8207650260c70416c9d0a6e954e433 711 Gene3D G3DSA:1.10.1040.50 491 709 4.7E-72 T 12-10-2018 VAPA_1c09050 cd8207650260c70416c9d0a6e954e433 711 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 488 581 6.9E-24 T 12-10-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 VAPA_1c09050 cd8207650260c70416c9d0a6e954e433 711 SUPERFAMILY SSF48179 613 704 1.7E-19 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 VAPA_1c09050 cd8207650260c70416c9d0a6e954e433 711 SUPERFAMILY SSF51735 306 484 2.17E-50 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c09050 cd8207650260c70416c9d0a6e954e433 711 SUPERFAMILY SSF52096 12 296 1.43E-68 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily VAPA_1c09050 cd8207650260c70416c9d0a6e954e433 711 Gene3D G3DSA:3.40.50.720 305 490 4.8E-60 T 12-10-2018 VAPA_1c09050 cd8207650260c70416c9d0a6e954e433 711 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 102 122 - T 12-10-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824 VAPA_1c09050 cd8207650260c70416c9d0a6e954e433 711 Gene3D G3DSA:3.90.226.10 12 304 7.7E-89 T 12-10-2018 VAPA_2c03830 bd48cd31362c6190ce643981cb3448bb 296 Gene3D G3DSA:3.60.15.10 4 288 5.1E-109 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like VAPA_2c03830 bd48cd31362c6190ce643981cb3448bb 296 Pfam PF00753 Metallo-beta-lactamase superfamily 15 200 1.1E-20 T 12-10-2018 IPR001279 Metallo-beta-lactamase VAPA_2c03830 bd48cd31362c6190ce643981cb3448bb 296 SMART SM00849 16 206 1.3E-25 T 12-10-2018 IPR001279 Metallo-beta-lactamase VAPA_2c03830 bd48cd31362c6190ce643981cb3448bb 296 SUPERFAMILY SSF56281 10 290 2.62E-51 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like VAPA_2c07750 3a12122cf036c0d2b9b175c518964d37 227 SUPERFAMILY SSF63829 22 222 8.5E-22 T 12-10-2018 VAPA_2c07750 3a12122cf036c0d2b9b175c518964d37 227 Gene3D G3DSA:2.130.10.10 16 223 5.0E-13 T 12-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 VAPA_2c07570 49e9ac1c33bba0eb9ce4c642f7e1bb2b 139 SMART SM00116 75 123 1.4E-7 T 12-10-2018 IPR000644 CBS domain VAPA_2c07570 49e9ac1c33bba0eb9ce4c642f7e1bb2b 139 SMART SM00116 11 58 3.6E-4 T 12-10-2018 IPR000644 CBS domain VAPA_2c07570 49e9ac1c33bba0eb9ce4c642f7e1bb2b 139 SUPERFAMILY SSF54631 2 119 4.93E-32 T 12-10-2018 VAPA_2c07570 49e9ac1c33bba0eb9ce4c642f7e1bb2b 139 Pfam PF00571 CBS domain 68 120 4.3E-10 T 12-10-2018 IPR000644 CBS domain VAPA_2c07570 49e9ac1c33bba0eb9ce4c642f7e1bb2b 139 Pfam PF00571 CBS domain 4 54 7.1E-11 T 12-10-2018 IPR000644 CBS domain VAPA_2c07570 49e9ac1c33bba0eb9ce4c642f7e1bb2b 139 Gene3D G3DSA:3.10.580.10 1 137 4.0E-34 T 12-10-2018 VAPA_1c23660 0121e87840bd965cf374e2ca339c3033 316 Gene3D G3DSA:1.10.260.40 17 112 2.1E-19 T 12-10-2018 VAPA_1c23660 0121e87840bd965cf374e2ca339c3033 316 Pfam PF13464 Domain of unknown function (DUF4115) 240 314 1.4E-19 T 12-10-2018 IPR025194 Domain of unknown function DUF4115 VAPA_1c23660 0121e87840bd965cf374e2ca339c3033 316 Pfam PF13413 Helix-turn-helix domain 29 90 4.7E-18 T 12-10-2018 VAPA_1c01670 9e47916681481102ae72d6b702258ebe 240 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_1c01670 9e47916681481102ae72d6b702258ebe 240 SUPERFAMILY SSF52540 10 231 3.11E-56 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c01670 9e47916681481102ae72d6b702258ebe 240 Gene3D G3DSA:3.40.50.300 6 238 7.1E-56 T 12-10-2018 VAPA_1c01670 9e47916681481102ae72d6b702258ebe 240 Pfam PF00005 ABC transporter 26 165 1.8E-32 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c01670 9e47916681481102ae72d6b702258ebe 240 SMART SM00382 35 215 6.1E-8 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c38770 52656eb8572f800c311b20dda0f10191 181 SUPERFAMILY SSF88659 103 174 5.42E-13 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like VAPA_1c38770 52656eb8572f800c311b20dda0f10191 181 Gene3D G3DSA:1.10.1740.10 11 82 4.3E-6 T 12-10-2018 VAPA_1c38770 52656eb8572f800c311b20dda0f10191 181 Pfam PF04542 Sigma-70 region 2 23 84 1.8E-8 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 VAPA_1c38770 52656eb8572f800c311b20dda0f10191 181 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 18 173 5.6E-20 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 VAPA_1c38770 52656eb8572f800c311b20dda0f10191 181 Pfam PF08281 Sigma-70, region 4 119 167 3.9E-11 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 VAPA_1c38770 52656eb8572f800c311b20dda0f10191 181 SUPERFAMILY SSF88946 16 96 3.37E-11 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 VAPA_1c38770 52656eb8572f800c311b20dda0f10191 181 Gene3D G3DSA:1.10.10.10 98 177 7.8E-12 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c46630 f9ef707bbb43c9b44d3aa22d211e4299 145 SUPERFAMILY SSF55785 16 131 4.67E-25 T 12-10-2018 IPR035965 PAS domain superfamily VAPA_1c46630 f9ef707bbb43c9b44d3aa22d211e4299 145 Pfam PF00989 PAS fold 6 119 1.1E-14 T 12-10-2018 IPR013767 PAS fold GO:0006355 VAPA_1c46630 f9ef707bbb43c9b44d3aa22d211e4299 145 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 7 130 6.9E-21 T 12-10-2018 IPR000014 PAS domain VAPA_1c46630 f9ef707bbb43c9b44d3aa22d211e4299 145 SMART SM00091 5 71 7.5E-12 T 12-10-2018 IPR000014 PAS domain VAPA_1c46630 f9ef707bbb43c9b44d3aa22d211e4299 145 Gene3D G3DSA:3.30.450.20 2 142 2.3E-27 T 12-10-2018 VAPA_1c42370 3f8b5ef834c0d6a82a637aa9fa051f41 251 SUPERFAMILY SSF52096 5 251 4.21E-60 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily VAPA_1c42370 3f8b5ef834c0d6a82a637aa9fa051f41 251 Gene3D G3DSA:1.10.12.10 197 249 1.2E-10 T 12-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal VAPA_1c42370 3f8b5ef834c0d6a82a637aa9fa051f41 251 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 93 113 - T 12-10-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824 VAPA_1c42370 3f8b5ef834c0d6a82a637aa9fa051f41 251 Pfam PF00378 Enoyl-CoA hydratase/isomerase 8 250 1.3E-32 T 12-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 VAPA_1c42370 3f8b5ef834c0d6a82a637aa9fa051f41 251 Gene3D G3DSA:3.90.226.10 4 194 2.2E-45 T 12-10-2018 VAPA_2c10360 e29f0c46348f7c13ee8250bf62046251 318 SUPERFAMILY SSF53850 106 279 3.62E-12 T 12-10-2018 VAPA_2c10360 e29f0c46348f7c13ee8250bf62046251 318 Gene3D G3DSA:3.40.190.10 120 243 3.4E-98 T 12-10-2018 VAPA_2c10360 e29f0c46348f7c13ee8250bf62046251 318 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 41 314 3.8E-74 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_2c10360 e29f0c46348f7c13ee8250bf62046251 318 PIRSF PIRSF017082 2 318 7.8E-68 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_2c10360 e29f0c46348f7c13ee8250bf62046251 318 Gene3D G3DSA:3.40.190.150 25 308 3.4E-98 T 12-10-2018 VAPA_1c13580 bf751001b71110f30dac53a09a04546d 265 ProSitePatterns PS00211 ABC transporters family signature. 166 180 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_1c13580 bf751001b71110f30dac53a09a04546d 265 PIRSF PIRSF039137 28 265 7.5E-104 T 12-10-2018 IPR030660 High-affinity branched-chain amino acid transport ATP-binding protein GO:0015658|GO:0015803 VAPA_1c13580 bf751001b71110f30dac53a09a04546d 265 Pfam PF00005 ABC transporter 49 193 1.3E-27 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c13580 bf751001b71110f30dac53a09a04546d 265 SUPERFAMILY SSF52540 30 264 4.99E-59 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c13580 bf751001b71110f30dac53a09a04546d 265 Gene3D G3DSA:3.40.50.300 28 265 7.9E-62 T 12-10-2018 VAPA_1c13580 bf751001b71110f30dac53a09a04546d 265 SMART SM00382 57 244 4.6E-6 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_2c10410 4936252134137c02b0b3dad04c717b8a 286 Pfam PF02653 Branched-chain amino acid transport system / permease component 6 257 1.8E-27 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 VAPA_1c16000 c2eea1ca80be6faed0eb8b48d284de98 534 Gene3D G3DSA:3.30.300.30 417 516 9.7E-27 T 12-10-2018 VAPA_1c16000 c2eea1ca80be6faed0eb8b48d284de98 534 Pfam PF00501 AMP-binding enzyme 19 421 1.9E-73 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 VAPA_1c16000 c2eea1ca80be6faed0eb8b48d284de98 534 Gene3D G3DSA:3.40.50.12780 14 416 4.6E-89 T 12-10-2018 VAPA_1c16000 c2eea1ca80be6faed0eb8b48d284de98 534 ProSitePatterns PS00455 Putative AMP-binding domain signature. 178 189 - T 12-10-2018 IPR020845 AMP-binding, conserved site VAPA_1c16000 c2eea1ca80be6faed0eb8b48d284de98 534 Pfam PF13193 AMP-binding enzyme C-terminal domain 430 505 3.5E-16 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain VAPA_1c16000 c2eea1ca80be6faed0eb8b48d284de98 534 SUPERFAMILY SSF56801 11 518 4.84E-125 T 12-10-2018 VAPA_1c50380 b66e892157652d0dd9e0a593996f505d 404 SUPERFAMILY SSF51905 1 370 1.23E-32 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c50380 b66e892157652d0dd9e0a593996f505d 404 Gene3D G3DSA:3.50.50.60 2 375 2.3E-45 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c50380 b66e892157652d0dd9e0a593996f505d 404 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 289 304 1.9E-12 T 12-10-2018 VAPA_1c50380 b66e892157652d0dd9e0a593996f505d 404 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 2 24 1.9E-12 T 12-10-2018 VAPA_1c50380 b66e892157652d0dd9e0a593996f505d 404 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 304 320 1.9E-12 T 12-10-2018 VAPA_1c50380 b66e892157652d0dd9e0a593996f505d 404 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 153 168 1.9E-12 T 12-10-2018 VAPA_1c50380 b66e892157652d0dd9e0a593996f505d 404 Pfam PF01494 FAD binding domain 2 355 2.9E-9 T 12-10-2018 IPR002938 FAD-binding domain GO:0071949 VAPA_1c03380 59f0ef1e9e90138a312bfa05f7801317 412 Gene3D G3DSA:3.50.50.60 5 346 7.8E-104 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c03380 59f0ef1e9e90138a312bfa05f7801317 412 Gene3D G3DSA:3.30.9.30 37 285 7.8E-104 T 12-10-2018 VAPA_1c03380 59f0ef1e9e90138a312bfa05f7801317 412 SUPERFAMILY SSF54373 176 282 2.75E-33 T 12-10-2018 VAPA_1c03380 59f0ef1e9e90138a312bfa05f7801317 412 Pfam PF01494 FAD binding domain 4 167 2.0E-10 T 12-10-2018 IPR002938 FAD-binding domain GO:0071949 VAPA_1c03380 59f0ef1e9e90138a312bfa05f7801317 412 Pfam PF01494 FAD binding domain 287 345 1.9E-5 T 12-10-2018 IPR002938 FAD-binding domain GO:0071949 VAPA_1c03380 59f0ef1e9e90138a312bfa05f7801317 412 SUPERFAMILY SSF51905 4 357 4.82E-59 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c03380 59f0ef1e9e90138a312bfa05f7801317 412 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 150 165 3.4E-19 T 12-10-2018 VAPA_1c03380 59f0ef1e9e90138a312bfa05f7801317 412 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 291 306 3.4E-19 T 12-10-2018 VAPA_1c03380 59f0ef1e9e90138a312bfa05f7801317 412 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 306 322 3.4E-19 T 12-10-2018 VAPA_1c03380 59f0ef1e9e90138a312bfa05f7801317 412 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 4 26 3.4E-19 T 12-10-2018 VAPA_1c09440 ff8efd08e00f7c78de5a94ffe4880609 783 TIGRFAM TIGR03396 PC_PLC: phospholipase C, phosphocholine-specific 3 686 4.0E-248 T 12-10-2018 IPR017767 Bacterial phospholipase C, phosphocholine-specific GO:0034480 KEGG: 00562+3.1.4.3|KEGG: 00564+3.1.4.3|KEGG: 00565+3.1.4.3|MetaCyc: PWY-7782|MetaCyc: PWY-7783 VAPA_1c09440 ff8efd08e00f7c78de5a94ffe4880609 783 Pfam PF04185 Phosphoesterase family 313 478 1.8E-49 T 12-10-2018 IPR007312 Phosphoesterase GO:0016788 VAPA_1c09440 ff8efd08e00f7c78de5a94ffe4880609 783 Pfam PF04185 Phosphoesterase family 46 274 7.8E-52 T 12-10-2018 IPR007312 Phosphoesterase GO:0016788 VAPA_1c09440 ff8efd08e00f7c78de5a94ffe4880609 783 Gene3D G3DSA:3.40.720.10 326 527 1.7E-48 T 12-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 VAPA_1c09440 ff8efd08e00f7c78de5a94ffe4880609 783 Gene3D G3DSA:3.40.720.10 36 210 3.9E-31 T 12-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 VAPA_1c09440 ff8efd08e00f7c78de5a94ffe4880609 783 Pfam PF05506 Domain of unknown function (DUF756) 550 640 1.5E-24 T 12-10-2018 IPR008475 Bacterial phospholipase C, C-terminal domain GO:0004629|GO:0016042 KEGG: 00562+3.1.4.3|KEGG: 00564+3.1.4.3|KEGG: 00565+3.1.4.3|MetaCyc: PWY-7782|MetaCyc: PWY-7783 VAPA_1c09440 ff8efd08e00f7c78de5a94ffe4880609 783 Pfam PF05506 Domain of unknown function (DUF756) 652 764 9.8E-21 T 12-10-2018 IPR008475 Bacterial phospholipase C, C-terminal domain GO:0004629|GO:0016042 KEGG: 00562+3.1.4.3|KEGG: 00564+3.1.4.3|KEGG: 00565+3.1.4.3|MetaCyc: PWY-7782|MetaCyc: PWY-7783 VAPA_1c45230 b1ac886c695eade42f30aa4c1244981e 276 ProSitePatterns PS00211 ABC transporters family signature. 161 175 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_1c45230 b1ac886c695eade42f30aa4c1244981e 276 Gene3D G3DSA:3.40.50.300 9 272 5.9E-86 T 12-10-2018 VAPA_1c45230 b1ac886c695eade42f30aa4c1244981e 276 SMART SM00382 46 237 1.7E-10 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c45230 b1ac886c695eade42f30aa4c1244981e 276 SUPERFAMILY SSF52540 10 260 1.84E-72 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c45230 b1ac886c695eade42f30aa4c1244981e 276 Pfam PF00005 ABC transporter 37 188 1.4E-31 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c45230 b1ac886c695eade42f30aa4c1244981e 276 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 240 267 1.1E-6 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 VAPA_1c14020 99a795dae641fa3bb012ad680260feb5 913 Pfam PF07519 Tannase and feruloyl esterase 117 591 5.1E-119 T 12-10-2018 IPR011118 Tannase/feruloyl esterase MetaCyc: PWY-6784 VAPA_1c14020 99a795dae641fa3bb012ad680260feb5 913 SUPERFAMILY SSF53474 209 529 7.18E-13 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_2c12630 4d0ad06b6c69a9337a9f1c91ae491a3b 486 Gene3D G3DSA:3.30.450.20 209 318 1.6E-8 T 12-10-2018 VAPA_2c12630 4d0ad06b6c69a9337a9f1c91ae491a3b 486 Gene3D G3DSA:3.30.450.20 50 172 2.1E-7 T 12-10-2018 VAPA_2c12630 4d0ad06b6c69a9337a9f1c91ae491a3b 486 SUPERFAMILY SSF55785 58 158 1.54E-7 T 12-10-2018 IPR035965 PAS domain superfamily VAPA_2c12630 4d0ad06b6c69a9337a9f1c91ae491a3b 486 SUPERFAMILY SSF55073 329 474 1.96E-33 T 12-10-2018 IPR029787 Nucleotide cyclase VAPA_2c12630 4d0ad06b6c69a9337a9f1c91ae491a3b 486 Pfam PF00990 Diguanylate cyclase, GGDEF domain 325 474 1.7E-34 T 12-10-2018 IPR000160 GGDEF domain VAPA_2c12630 4d0ad06b6c69a9337a9f1c91ae491a3b 486 Gene3D G3DSA:3.30.70.270 319 478 9.0E-40 T 12-10-2018 VAPA_2c12630 4d0ad06b6c69a9337a9f1c91ae491a3b 486 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 320 474 1.2E-27 T 12-10-2018 IPR000160 GGDEF domain VAPA_2c12630 4d0ad06b6c69a9337a9f1c91ae491a3b 486 SMART SM00267 313 483 5.4E-33 T 12-10-2018 IPR000160 GGDEF domain VAPA_2c12630 4d0ad06b6c69a9337a9f1c91ae491a3b 486 SUPERFAMILY SSF55785 217 320 7.89E-9 T 12-10-2018 IPR035965 PAS domain superfamily VAPA_2c12630 4d0ad06b6c69a9337a9f1c91ae491a3b 486 Pfam PF13188 PAS domain 166 264 3.7E-7 T 12-10-2018 IPR000014 PAS domain VAPA_2c12630 4d0ad06b6c69a9337a9f1c91ae491a3b 486 Pfam PF13188 PAS domain 7 93 5.2E-4 T 12-10-2018 IPR000014 PAS domain VAPA_2c10990 3c05065ce2a0ccadcf29158f2bc8e5ce 374 Gene3D G3DSA:1.10.287.130 166 218 5.7E-29 T 12-10-2018 VAPA_2c10990 3c05065ce2a0ccadcf29158f2bc8e5ce 374 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 267 371 2.0E-14 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase VAPA_2c10990 3c05065ce2a0ccadcf29158f2bc8e5ce 374 SUPERFAMILY SSF55874 223 371 8.19E-31 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_2c10990 3c05065ce2a0ccadcf29158f2bc8e5ce 374 Gene3D G3DSA:3.30.565.10 219 369 5.7E-29 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_2c10990 3c05065ce2a0ccadcf29158f2bc8e5ce 374 PRINTS PR00344 Bacterial sensor protein C-terminal signature 356 369 5.8E-10 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_2c10990 3c05065ce2a0ccadcf29158f2bc8e5ce 374 PRINTS PR00344 Bacterial sensor protein C-terminal signature 301 315 5.8E-10 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_2c10990 3c05065ce2a0ccadcf29158f2bc8e5ce 374 PRINTS PR00344 Bacterial sensor protein C-terminal signature 332 350 5.8E-10 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_2c10990 3c05065ce2a0ccadcf29158f2bc8e5ce 374 SMART SM00387 264 372 7.2E-20 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase VAPA_1c06910 781e051d9b4cb62003ca2052be88902d 392 Pfam PF13458 Periplasmic binding protein 31 366 1.1E-64 T 12-10-2018 IPR028081 Leucine-binding protein domain VAPA_1c06910 781e051d9b4cb62003ca2052be88902d 392 Gene3D G3DSA:3.40.50.2300 32 355 1.2E-88 T 12-10-2018 VAPA_1c06910 781e051d9b4cb62003ca2052be88902d 392 Gene3D G3DSA:3.40.50.2300 147 361 1.2E-88 T 12-10-2018 VAPA_1c06910 781e051d9b4cb62003ca2052be88902d 392 SUPERFAMILY SSF53822 31 370 1.35E-79 T 12-10-2018 IPR028082 Periplasmic binding protein-like I VAPA_2c01660 6414ea646c0a3f8be566ba4bf2e1abd6 137 Gene3D G3DSA:3.40.630.30 5 131 1.1E-23 T 12-10-2018 VAPA_2c01660 6414ea646c0a3f8be566ba4bf2e1abd6 137 SUPERFAMILY SSF55729 1 123 7.8E-21 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase VAPA_2c01660 6414ea646c0a3f8be566ba4bf2e1abd6 137 Pfam PF13673 Acetyltransferase (GNAT) domain 30 122 4.4E-12 T 12-10-2018 IPR000182 GNAT domain VAPA_1c05730 941b47ed3ad94e76d33736550b6b1781 656 PIRSF PIRSF015380 2 656 1.1E-176 T 12-10-2018 IPR011385 Putative site-specific recombinase Gcr VAPA_1c05730 941b47ed3ad94e76d33736550b6b1781 656 Pfam PF10136 Site-specific recombinase 23 655 4.7E-225 T 12-10-2018 IPR011385 Putative site-specific recombinase Gcr VAPA_1c08760 dc5215380c6c3f0f0181a93faf3ca314 298 Gene3D G3DSA:3.40.50.1820 1 267 3.8E-32 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c08760 dc5215380c6c3f0f0181a93faf3ca314 298 Pfam PF12146 Serine aminopeptidase, S33 24 150 1.5E-18 T 12-10-2018 IPR022742 Serine aminopeptidase, S33 VAPA_1c08760 dc5215380c6c3f0f0181a93faf3ca314 298 SUPERFAMILY SSF53474 2 244 3.41E-31 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c08760 dc5215380c6c3f0f0181a93faf3ca314 298 PIRSF PIRSF037442 1 284 5.5E-89 T 12-10-2018 IPR017208 Uncharacterised conserved protein UCP037442, alpha/beta hydrolase, RSp0795 VAPA_2c01890 82c0f84a723b865b88397255049a49bc 331 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 53 327 1.6E-81 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_2c01890 82c0f84a723b865b88397255049a49bc 331 SUPERFAMILY SSF53850 120 290 1.1E-13 T 12-10-2018 VAPA_2c01890 82c0f84a723b865b88397255049a49bc 331 PIRSF PIRSF017082 2 331 2.4E-73 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_2c01890 82c0f84a723b865b88397255049a49bc 331 Gene3D G3DSA:3.40.190.10 132 255 1.0E-111 T 12-10-2018 VAPA_2c01890 82c0f84a723b865b88397255049a49bc 331 Gene3D G3DSA:3.40.190.150 36 321 1.0E-111 T 12-10-2018 VAPA_1c29430 1d0a6c049570300b76981889080d8c5a 325 Gene3D G3DSA:2.160.10.10 98 292 8.3E-55 T 12-10-2018 VAPA_1c29430 1d0a6c049570300b76981889080d8c5a 325 Hamap MF_00523 UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase [lpxD]. 8 311 31.594 T 12-10-2018 IPR007691 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD GO:0009245|GO:0016410 VAPA_1c29430 1d0a6c049570300b76981889080d8c5a 325 TIGRFAM TIGR01853 lipid_A_lpxD: UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD 8 314 6.1E-93 T 12-10-2018 IPR007691 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD GO:0009245|GO:0016410 VAPA_1c29430 1d0a6c049570300b76981889080d8c5a 325 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 115 143 - T 12-10-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 VAPA_1c29430 1d0a6c049570300b76981889080d8c5a 325 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 131 164 1.0E-5 T 12-10-2018 IPR001451 Hexapeptide repeat VAPA_1c29430 1d0a6c049570300b76981889080d8c5a 325 Gene3D G3DSA:3.40.1390.10 2 97 1.1E-25 T 12-10-2018 VAPA_1c29430 1d0a6c049570300b76981889080d8c5a 325 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 245 278 0.005 T 12-10-2018 IPR001451 Hexapeptide repeat VAPA_1c29430 1d0a6c049570300b76981889080d8c5a 325 SUPERFAMILY SSF51161 32 301 8.21E-69 T 12-10-2018 IPR011004 Trimeric LpxA-like superfamily VAPA_1c29430 1d0a6c049570300b76981889080d8c5a 325 Pfam PF04613 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD 23 90 8.6E-22 T 12-10-2018 IPR020573 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, non-repeat region GO:0009245|GO:0016747 VAPA_1c53980 26352a4967fc937898910f39ce0ee738 228 TIGRFAM TIGR03717 R_switched_YjbE: integral membrane protein, YjbE family 13 186 4.1E-68 T 12-10-2018 IPR022301 Integral membrane protein YjbE VAPA_1c53980 26352a4967fc937898910f39ce0ee738 228 Pfam PF03741 Integral membrane protein TerC family 15 184 1.3E-45 T 12-10-2018 IPR005496 Integral membrane protein TerC GO:0016021 VAPA_1c28070 2aef98f800fb20efde17a50fe2c58340 611 SUPERFAMILY SSF54980 404 517 1.49E-28 T 12-10-2018 IPR035647 EF-G domain III/V-like VAPA_1c28070 2aef98f800fb20efde17a50fe2c58340 611 Gene3D G3DSA:3.40.50.300 3 202 7.8E-63 T 12-10-2018 VAPA_1c28070 2aef98f800fb20efde17a50fe2c58340 611 Gene3D G3DSA:3.30.70.240 395 487 3.0E-126 T 12-10-2018 VAPA_1c28070 2aef98f800fb20efde17a50fe2c58340 611 SUPERFAMILY SSF54980 308 393 1.33E-13 T 12-10-2018 IPR035647 EF-G domain III/V-like VAPA_1c28070 2aef98f800fb20efde17a50fe2c58340 611 TIGRFAM TIGR01394 TypA_BipA: GTP-binding protein TypA/BipA 6 604 1.2E-274 T 12-10-2018 IPR006298 GTP-binding protein TypA GO:0005525 VAPA_1c28070 2aef98f800fb20efde17a50fe2c58340 611 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 5 140 1.4E-25 T 12-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 VAPA_1c28070 2aef98f800fb20efde17a50fe2c58340 611 Gene3D G3DSA:2.40.50.250 488 604 3.0E-126 T 12-10-2018 VAPA_1c28070 2aef98f800fb20efde17a50fe2c58340 611 Gene3D G3DSA:2.40.30.10 204 305 2.8E-26 T 12-10-2018 VAPA_1c28070 2aef98f800fb20efde17a50fe2c58340 611 SUPERFAMILY SSF52540 3 211 1.49E-55 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c28070 2aef98f800fb20efde17a50fe2c58340 611 Pfam PF00679 Elongation factor G C-terminus 403 486 9.7E-20 T 12-10-2018 IPR000640 Elongation factor EFG, domain V-like VAPA_1c28070 2aef98f800fb20efde17a50fe2c58340 611 Pfam PF00009 Elongation factor Tu GTP binding domain 4 200 4.9E-56 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 VAPA_1c28070 2aef98f800fb20efde17a50fe2c58340 611 SUPERFAMILY SSF50447 152 305 2.78E-27 T 12-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily VAPA_1c28070 2aef98f800fb20efde17a50fe2c58340 611 PRINTS PR00315 GTP-binding elongation factor signature 52 60 1.6E-15 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 VAPA_1c28070 2aef98f800fb20efde17a50fe2c58340 611 PRINTS PR00315 GTP-binding elongation factor signature 72 82 1.6E-15 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 VAPA_1c28070 2aef98f800fb20efde17a50fe2c58340 611 PRINTS PR00315 GTP-binding elongation factor signature 8 21 1.6E-15 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 VAPA_1c28070 2aef98f800fb20efde17a50fe2c58340 611 PRINTS PR00315 GTP-binding elongation factor signature 88 99 1.6E-15 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 VAPA_1c28070 2aef98f800fb20efde17a50fe2c58340 611 PRINTS PR00315 GTP-binding elongation factor signature 124 133 1.6E-15 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 VAPA_1c28070 2aef98f800fb20efde17a50fe2c58340 611 Gene3D G3DSA:3.30.70.870 312 595 3.0E-126 T 12-10-2018 VAPA_1c28070 2aef98f800fb20efde17a50fe2c58340 611 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 45 60 - T 12-10-2018 IPR031157 Tr-type G domain, conserved site VAPA_1c11980 85bbc789bd2d4878b23b345ed6cfcf8e 774 SUPERFAMILY SSF56601 207 728 1.5E-116 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like VAPA_1c11980 85bbc789bd2d4878b23b345ed6cfcf8e 774 Pfam PF00905 Penicillin binding protein transpeptidase domain 418 692 7.5E-39 T 12-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 VAPA_1c11980 85bbc789bd2d4878b23b345ed6cfcf8e 774 Pfam PF17092 Penicillin-binding protein OB-like domain 312 416 1.2E-20 T 12-10-2018 IPR031376 Penicillin-binding protein, OB-like domain KEGG: 00550+2.4.1.129+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 VAPA_1c11980 85bbc789bd2d4878b23b345ed6cfcf8e 774 Gene3D G3DSA:3.40.710.10 239 380 8.3E-7 T 12-10-2018 VAPA_1c11980 85bbc789bd2d4878b23b345ed6cfcf8e 774 Pfam PF00912 Transglycosylase 54 226 3.9E-61 T 12-10-2018 IPR001264 Glycosyl transferase, family 51 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 VAPA_1c11980 85bbc789bd2d4878b23b345ed6cfcf8e 774 Gene3D G3DSA:1.10.3810.10 46 238 2.2E-71 T 12-10-2018 IPR036950 Penicillin binding protein transglycosylase domain KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 VAPA_1c11980 85bbc789bd2d4878b23b345ed6cfcf8e 774 SUPERFAMILY SSF53955 39 248 9.56E-71 T 12-10-2018 IPR023346 Lysozyme-like domain superfamily VAPA_1c11980 85bbc789bd2d4878b23b345ed6cfcf8e 774 Gene3D G3DSA:3.40.710.10 391 733 2.7E-106 T 12-10-2018 VAPA_1c11980 85bbc789bd2d4878b23b345ed6cfcf8e 774 TIGRFAM TIGR02074 PBP_1a_fam: penicillin-binding protein, 1A family 62 702 9.9E-181 T 12-10-2018 VAPA_2c10260 f772bf5ea71061e163812ba05fefb86b 157 SUPERFAMILY SSF46689 1 73 5.91E-11 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 VAPA_2c10260 f772bf5ea71061e163812ba05fefb86b 157 Pfam PF01527 Transposase 2 71 1.4E-15 T 12-10-2018 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 VAPA_1c31790 229421624dae0a5b677cf666c70c02a8 155 Pfam PF00885 6,7-dimethyl-8-ribityllumazine synthase 17 151 2.2E-46 T 12-10-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 VAPA_1c31790 229421624dae0a5b677cf666c70c02a8 155 Hamap MF_00178 6,7-dimethyl-8-ribityllumazine synthase [ribH]. 13 154 26.676 T 12-10-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 VAPA_1c31790 229421624dae0a5b677cf666c70c02a8 155 TIGRFAM TIGR00114 lumazine-synth: 6,7-dimethyl-8-ribityllumazine synthase 18 149 1.4E-38 T 12-10-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 VAPA_1c31790 229421624dae0a5b677cf666c70c02a8 155 Gene3D G3DSA:3.40.50.960 8 155 1.2E-50 T 12-10-2018 IPR036467 Lumazine/riboflavin synthase superfamily GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 VAPA_1c31790 229421624dae0a5b677cf666c70c02a8 155 SUPERFAMILY SSF52121 12 154 1.83E-50 T 12-10-2018 IPR036467 Lumazine/riboflavin synthase superfamily GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 VAPA_1c07600 4a919c7b951b5402274ee53d793dac68 228 SUPERFAMILY SSF53850 22 220 1.02E-39 T 12-10-2018 VAPA_1c07600 4a919c7b951b5402274ee53d793dac68 228 Gene3D G3DSA:3.40.190.290 21 223 3.1E-34 T 12-10-2018 VAPA_1c07600 4a919c7b951b5402274ee53d793dac68 228 Pfam PF03466 LysR substrate binding domain 21 219 3.4E-34 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_1c00400 38fcfaaebaec25674cde7988f4064efa 261 Gene3D G3DSA:3.90.226.10 6 258 2.3E-68 T 12-10-2018 VAPA_1c00400 38fcfaaebaec25674cde7988f4064efa 261 SUPERFAMILY SSF52096 10 261 1.77E-67 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily VAPA_1c00400 38fcfaaebaec25674cde7988f4064efa 261 Pfam PF00378 Enoyl-CoA hydratase/isomerase 18 260 1.1E-49 T 12-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 VAPA_1c17780 b2f76e3957f168b0ccd1b15c45db1e2d 319 Pfam PF08241 Methyltransferase domain 100 200 1.0E-8 T 12-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 VAPA_1c17780 b2f76e3957f168b0ccd1b15c45db1e2d 319 Gene3D G3DSA:3.40.50.150 25 265 1.2E-26 T 12-10-2018 VAPA_1c17780 b2f76e3957f168b0ccd1b15c45db1e2d 319 SUPERFAMILY SSF53335 34 317 1.1E-29 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase VAPA_1c19500 75bd73bf9f515948b9ed48ed89245a63 395 Gene3D G3DSA:3.20.20.500 1 389 3.2E-176 T 12-10-2018 VAPA_1c19500 75bd73bf9f515948b9ed48ed89245a63 395 Pfam PF06187 Protein of unknown function (DUF993) 5 393 2.5E-188 T 12-10-2018 IPR009334 Protein of unknown function DUF993 VAPA_1c19500 75bd73bf9f515948b9ed48ed89245a63 395 SUPERFAMILY SSF51569 58 341 9.77E-12 T 12-10-2018 VAPA_1c08570 1b2890cd95c43662018f0114b0d45e4e 236 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_1c08570 1b2890cd95c43662018f0114b0d45e4e 236 SMART SM00382 29 213 3.1E-6 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c08570 1b2890cd95c43662018f0114b0d45e4e 236 Pfam PF00005 ABC transporter 20 164 4.4E-29 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c08570 1b2890cd95c43662018f0114b0d45e4e 236 Gene3D G3DSA:3.40.50.300 2 236 4.5E-58 T 12-10-2018 VAPA_1c08570 1b2890cd95c43662018f0114b0d45e4e 236 SUPERFAMILY SSF52540 4 233 2.17E-56 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c15800 d3d05280898c04f433d69bca238adc7f 292 Gene3D G3DSA:3.90.180.10 10 119 4.7E-39 T 12-10-2018 VAPA_1c15800 d3d05280898c04f433d69bca238adc7f 292 SUPERFAMILY SSF50129 1 140 1.89E-26 T 12-10-2018 IPR011032 GroES-like superfamily VAPA_1c15800 d3d05280898c04f433d69bca238adc7f 292 SMART SM00829 8 290 3.3E-8 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 VAPA_1c15800 d3d05280898c04f433d69bca238adc7f 292 Pfam PF13602 Zinc-binding dehydrogenase 179 290 8.2E-10 T 12-10-2018 VAPA_1c15800 d3d05280898c04f433d69bca238adc7f 292 Gene3D G3DSA:3.90.180.10 259 289 3.6E-19 T 12-10-2018 VAPA_1c15800 d3d05280898c04f433d69bca238adc7f 292 Gene3D G3DSA:3.40.50.720 180 258 3.6E-19 T 12-10-2018 VAPA_1c15800 d3d05280898c04f433d69bca238adc7f 292 SUPERFAMILY SSF51735 112 248 1.74E-28 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c15800 d3d05280898c04f433d69bca238adc7f 292 Gene3D G3DSA:3.40.50.720 120 170 4.7E-39 T 12-10-2018 VAPA_2c10040 0f399d4508ddcf6ff58411a6e9e47089 308 SUPERFAMILY SSF46785 5 83 5.45E-18 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_2c10040 0f399d4508ddcf6ff58411a6e9e47089 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 22 33 4.6E-5 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_2c10040 0f399d4508ddcf6ff58411a6e9e47089 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 43 54 4.6E-5 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_2c10040 0f399d4508ddcf6ff58411a6e9e47089 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 33 43 4.6E-5 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_2c10040 0f399d4508ddcf6ff58411a6e9e47089 308 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 65 4.6E-15 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_2c10040 0f399d4508ddcf6ff58411a6e9e47089 308 Gene3D G3DSA:3.40.190.10 170 269 4.6E-61 T 12-10-2018 VAPA_2c10040 0f399d4508ddcf6ff58411a6e9e47089 308 Pfam PF03466 LysR substrate binding domain 95 298 5.0E-29 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_2c10040 0f399d4508ddcf6ff58411a6e9e47089 308 Gene3D G3DSA:1.10.10.10 2 86 1.7E-25 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_2c10040 0f399d4508ddcf6ff58411a6e9e47089 308 Gene3D G3DSA:3.40.190.10 92 293 4.6E-61 T 12-10-2018 VAPA_2c10040 0f399d4508ddcf6ff58411a6e9e47089 308 SUPERFAMILY SSF53850 91 297 3.98E-42 T 12-10-2018 VAPA_1c36310 16ed6cd0d58e3c047dcca5d68b4ee209 414 SUPERFAMILY SSF53850 43 282 8.69E-30 T 12-10-2018 VAPA_1c36310 16ed6cd0d58e3c047dcca5d68b4ee209 414 Pfam PF13379 NMT1-like family 39 288 9.9E-103 T 12-10-2018 VAPA_1c36310 16ed6cd0d58e3c047dcca5d68b4ee209 414 Gene3D G3DSA:3.40.190.10 132 403 6.7E-124 T 12-10-2018 VAPA_1c36310 16ed6cd0d58e3c047dcca5d68b4ee209 414 Gene3D G3DSA:3.40.190.10 46 398 6.7E-124 T 12-10-2018 VAPA_1c32040 ed8f8a011f698d9c3605ecf2e9e5c54b 255 SUPERFAMILY SSF53639 16 219 1.22E-59 T 12-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily VAPA_1c32040 ed8f8a011f698d9c3605ecf2e9e5c54b 255 SMART SM01007 22 202 4.2E-64 T 12-10-2018 IPR001303 Class II aldolase/adducin N-terminal VAPA_1c32040 ed8f8a011f698d9c3605ecf2e9e5c54b 255 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 23 202 2.8E-44 T 12-10-2018 IPR001303 Class II aldolase/adducin N-terminal VAPA_1c32040 ed8f8a011f698d9c3605ecf2e9e5c54b 255 Gene3D G3DSA:3.40.225.10 8 255 4.6E-71 T 12-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily VAPA_1c31670 a4069a445106f1c1ac4231a729e855d6 285 SUPERFAMILY SSF53955 122 239 3.56E-23 T 12-10-2018 IPR023346 Lysozyme-like domain superfamily VAPA_1c31670 a4069a445106f1c1ac4231a729e855d6 285 Pfam PF01464 Transglycosylase SLT domain 125 224 1.8E-17 T 12-10-2018 IPR008258 Transglycosylase SLT domain 1 VAPA_1c31670 a4069a445106f1c1ac4231a729e855d6 285 Gene3D G3DSA:1.10.530.10 117 237 6.1E-20 T 12-10-2018 VAPA_1c10600 996b0756f36a515bab06e29579edf307 626 Pfam PF13522 Glutamine amidotransferase domain 61 190 1.0E-18 T 12-10-2018 VAPA_1c10600 996b0756f36a515bab06e29579edf307 626 Gene3D G3DSA:3.40.50.10490 259 625 4.3E-136 T 12-10-2018 VAPA_1c10600 996b0756f36a515bab06e29579edf307 626 Hamap MF_00164 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] [glmS]. 1 626 38.288 T 12-10-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 VAPA_1c10600 996b0756f36a515bab06e29579edf307 626 TIGRFAM TIGR01135 glmS: glutamine-fructose-6-phosphate transaminase (isomerizing) 2 626 2.3E-236 T 12-10-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 VAPA_1c10600 996b0756f36a515bab06e29579edf307 626 Pfam PF01380 SIS domain 480 606 6.2E-23 T 12-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 VAPA_1c10600 996b0756f36a515bab06e29579edf307 626 Pfam PF01380 SIS domain 309 429 8.2E-27 T 12-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 VAPA_1c10600 996b0756f36a515bab06e29579edf307 626 Gene3D G3DSA:3.60.20.10 2 251 8.0E-71 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal VAPA_1c10600 996b0756f36a515bab06e29579edf307 626 SUPERFAMILY SSF53697 255 626 1.39E-106 T 12-10-2018 VAPA_1c10600 996b0756f36a515bab06e29579edf307 626 Gene3D G3DSA:3.40.50.10490 464 611 4.3E-136 T 12-10-2018 VAPA_1c10600 996b0756f36a515bab06e29579edf307 626 SUPERFAMILY SSF56235 2 244 1.54E-67 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal VAPA_1c49130 86914ff1db6df5145dc8f2e54c9129fe 287 SUPERFAMILY SSF102215 10 258 5.36E-72 T 12-10-2018 IPR024087 Creatininase-like superfamily KEGG: 00740+3.5.1.102|MetaCyc: PWY-6167 VAPA_1c49130 86914ff1db6df5145dc8f2e54c9129fe 287 Pfam PF02633 Creatinine amidohydrolase 15 254 3.7E-66 T 12-10-2018 IPR003785 Creatininase/formamide hydrolase KEGG: 00740+3.5.1.102|MetaCyc: PWY-6167 VAPA_1c49130 86914ff1db6df5145dc8f2e54c9129fe 287 Gene3D G3DSA:3.40.50.10310 9 260 7.4E-68 T 12-10-2018 IPR024087 Creatininase-like superfamily KEGG: 00740+3.5.1.102|MetaCyc: PWY-6167 VAPA_1c48790 1fdc20239d574447d09d345462b9d33e 342 SUPERFAMILY SSF46689 291 340 7.17E-12 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 VAPA_1c48790 1fdc20239d574447d09d345462b9d33e 342 Pfam PF12625 Arabinose-binding domain of AraC transcription regulator, N-term 30 213 5.4E-54 T 12-10-2018 IPR032687 HTH-type transcriptional regulator AraC-type, N-terminal VAPA_1c48790 1fdc20239d574447d09d345462b9d33e 342 Pfam PF12833 Helix-turn-helix domain 262 340 2.6E-19 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 VAPA_1c48790 1fdc20239d574447d09d345462b9d33e 342 Gene3D G3DSA:1.10.10.60 236 341 1.4E-24 T 12-10-2018 VAPA_1c48790 1fdc20239d574447d09d345462b9d33e 342 SMART SM00342 256 338 3.4E-21 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 VAPA_1c13700 7f14469cdaa0bc41d83f876b697b4154 192 Pfam PF14803 Nudix N-terminal 5 38 4.6E-7 T 12-10-2018 IPR029401 Nudix hydrolase, N-terminal KEGG: 00230+3.6.1.13|KEGG: 00740+3.6.1.18 VAPA_1c13700 7f14469cdaa0bc41d83f876b697b4154 192 Gene3D G3DSA:3.90.79.10 41 180 6.5E-22 T 12-10-2018 VAPA_1c13700 7f14469cdaa0bc41d83f876b697b4154 192 Pfam PF00293 NUDIX domain 47 144 3.9E-12 T 12-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 VAPA_1c13700 7f14469cdaa0bc41d83f876b697b4154 192 ProSitePatterns PS00893 Nudix box signature. 74 95 - T 12-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 VAPA_1c13700 7f14469cdaa0bc41d83f876b697b4154 192 SUPERFAMILY SSF55811 5 162 3.52E-29 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 VAPA_1c02200 6ba28f3b562009c26becb7a2dca3411a 267 SMART SM00382 28 222 9.4E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c02200 6ba28f3b562009c26becb7a2dca3411a 267 SUPERFAMILY SSF52540 3 244 1.2E-60 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c02200 6ba28f3b562009c26becb7a2dca3411a 267 Pfam PF00005 ABC transporter 20 173 3.5E-32 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c02200 6ba28f3b562009c26becb7a2dca3411a 267 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 222 244 6.9E-7 T 12-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal VAPA_1c02200 6ba28f3b562009c26becb7a2dca3411a 267 Gene3D G3DSA:3.40.50.300 1 245 5.3E-62 T 12-10-2018 VAPA_2c06570 ab97b11a059d7f84bde53c2f3659ef30 57 SUPERFAMILY SSF53901 16 56 1.36E-10 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 VAPA_2c06570 ab97b11a059d7f84bde53c2f3659ef30 57 Pfam PF02803 Thiolase, C-terminal domain 16 56 1.9E-12 T 12-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 VAPA_2c06570 ab97b11a059d7f84bde53c2f3659ef30 57 Gene3D G3DSA:3.40.47.10 14 57 3.3E-12 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 VAPA_2c06570 ab97b11a059d7f84bde53c2f3659ef30 57 ProSitePatterns PS00099 Thiolases active site. 38 51 - T 12-10-2018 IPR020610 Thiolase, active site GO:0016747 VAPA_1c35250 07d9921697c31e5d61845c8af7efbe4c 217 Gene3D G3DSA:1.10.3720.10 8 214 5.4E-47 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c35250 07d9921697c31e5d61845c8af7efbe4c 217 SUPERFAMILY SSF161098 12 203 2.09E-40 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c35250 07d9921697c31e5d61845c8af7efbe4c 217 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 30 210 1.7E-16 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 VAPA_1c35250 07d9921697c31e5d61845c8af7efbe4c 217 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 10 106 6.4E-30 T 12-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 VAPA_1c04830 27cca569d9e43e829198869d24292011 319 SUPERFAMILY SSF75138 11 139 7.06E-30 T 12-10-2018 IPR028979 HPr(Ser) kinase/phosphorylase-like, N-terminal domain superfamily VAPA_1c04830 27cca569d9e43e829198869d24292011 319 Gene3D G3DSA:3.40.1390.20 12 138 1.4E-23 T 12-10-2018 IPR028979 HPr(Ser) kinase/phosphorylase-like, N-terminal domain superfamily VAPA_1c04830 27cca569d9e43e829198869d24292011 319 Hamap MF_01249 HPr kinase/phosphorylase [hprK]. 5 315 35.084 T 12-10-2018 IPR003755 HPr(Ser) kinase/phosphorylase GO:0000155|GO:0000160|GO:0005524|GO:0006109 VAPA_1c04830 27cca569d9e43e829198869d24292011 319 Pfam PF07475 HPr Serine kinase C-terminal domain 138 307 9.2E-60 T 12-10-2018 IPR011104 HPr kinase/phosphorylase, C-terminal GO:0000155|GO:0000160|GO:0004672|GO:0005524|GO:0006109 VAPA_1c04830 27cca569d9e43e829198869d24292011 319 SUPERFAMILY SSF53795 140 307 2.26E-32 T 12-10-2018 VAPA_1c04830 27cca569d9e43e829198869d24292011 319 Gene3D G3DSA:3.40.50.300 139 319 2.9E-60 T 12-10-2018 VAPA_1c04830 27cca569d9e43e829198869d24292011 319 Pfam PF02603 HPr Serine kinase N terminus 9 135 2.6E-22 T 12-10-2018 IPR011126 HPr(Ser) kinase/phosphorylase, N-terminal GO:0000155|GO:0000160|GO:0004672|GO:0005524|GO:0006109 VAPA_1c04830 27cca569d9e43e829198869d24292011 319 TIGRFAM TIGR00679 hpr-ser: HPr(Ser) kinase/phosphatase 15 312 3.0E-94 T 12-10-2018 IPR003755 HPr(Ser) kinase/phosphorylase GO:0000155|GO:0000160|GO:0005524|GO:0006109 VAPA_1c50890 4f9f7d49485ad704ee1a808a5e5362c6 308 Hamap MF_01309_B 30S ribosomal protein S3 [rpsC]. 1 206 39.226 T 12-10-2018 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 VAPA_1c50890 4f9f7d49485ad704ee1a808a5e5362c6 308 Gene3D G3DSA:3.30.300.20 17 107 1.8E-29 T 12-10-2018 IPR015946 K homology domain-like, alpha/beta VAPA_1c50890 4f9f7d49485ad704ee1a808a5e5362c6 308 ProSitePatterns PS00548 Ribosomal protein S3 signature. 163 197 - T 12-10-2018 IPR018280 Ribosomal protein S3, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VAPA_1c50890 4f9f7d49485ad704ee1a808a5e5362c6 308 SUPERFAMILY SSF54814 2 106 6.98E-38 T 12-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 VAPA_1c50890 4f9f7d49485ad704ee1a808a5e5362c6 308 SUPERFAMILY SSF54821 108 206 3.14E-39 T 12-10-2018 IPR036419 Ribosomal protein S3, C-terminal domain superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VAPA_1c50890 4f9f7d49485ad704ee1a808a5e5362c6 308 Gene3D G3DSA:3.30.1140.32 108 208 1.2E-43 T 12-10-2018 IPR036419 Ribosomal protein S3, C-terminal domain superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VAPA_1c50890 4f9f7d49485ad704ee1a808a5e5362c6 308 SMART SM00322 60 125 1.1E-8 T 12-10-2018 IPR004087 K Homology domain GO:0003676 VAPA_1c50890 4f9f7d49485ad704ee1a808a5e5362c6 308 Pfam PF07650 KH domain 38 110 1.9E-20 T 12-10-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VAPA_1c50890 4f9f7d49485ad704ee1a808a5e5362c6 308 Pfam PF00189 Ribosomal protein S3, C-terminal domain 120 202 1.0E-39 T 12-10-2018 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VAPA_1c50890 4f9f7d49485ad704ee1a808a5e5362c6 308 TIGRFAM TIGR01009 rpsC_bact: ribosomal protein uS3 1 209 1.1E-93 T 12-10-2018 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 VAPA_1c51190 6c9bfe5919f88b36f042d045c40f112a 257 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_1c51190 6c9bfe5919f88b36f042d045c40f112a 257 PIRSF PIRSF039137 1 240 5.7E-104 T 12-10-2018 IPR030660 High-affinity branched-chain amino acid transport ATP-binding protein GO:0015658|GO:0015803 VAPA_1c51190 6c9bfe5919f88b36f042d045c40f112a 257 SUPERFAMILY SSF52540 4 237 3.13E-57 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c51190 6c9bfe5919f88b36f042d045c40f112a 257 SMART SM00382 30 216 6.9E-7 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c51190 6c9bfe5919f88b36f042d045c40f112a 257 Gene3D G3DSA:3.40.50.300 1 240 2.1E-62 T 12-10-2018 VAPA_1c51190 6c9bfe5919f88b36f042d045c40f112a 257 Pfam PF00005 ABC transporter 22 166 1.5E-30 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c30860 7acb4f0ea3e0374f30dde1b5678329bd 278 TIGRFAM TIGR00129 fdhD_narQ: formate dehydrogenase family accessory protein FdhD 31 271 1.1E-61 T 12-10-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 VAPA_1c30860 7acb4f0ea3e0374f30dde1b5678329bd 278 SUPERFAMILY SSF53927 26 271 2.98E-77 T 12-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 VAPA_1c30860 7acb4f0ea3e0374f30dde1b5678329bd 278 Pfam PF02634 FdhD/NarQ family 34 271 5.9E-73 T 12-10-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 VAPA_1c30860 7acb4f0ea3e0374f30dde1b5678329bd 278 Gene3D G3DSA:3.40.140.10 126 274 3.1E-50 T 12-10-2018 VAPA_1c30860 7acb4f0ea3e0374f30dde1b5678329bd 278 PIRSF PIRSF015626 14 274 3.6E-75 T 12-10-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 VAPA_1c30860 7acb4f0ea3e0374f30dde1b5678329bd 278 Hamap MF_00187 Sulfur carrier protein FdhD [fdhD]. 10 272 34.373 T 12-10-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 VAPA_1c52890 d54115f0edf93536027d26cf656100ea 169 Pfam PF01037 Lrp/AsnC ligand binding domain 86 160 2.1E-19 T 12-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain VAPA_1c52890 d54115f0edf93536027d26cf656100ea 169 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 20 36 1.5E-10 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 VAPA_1c52890 d54115f0edf93536027d26cf656100ea 169 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 36 47 1.5E-10 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 VAPA_1c52890 d54115f0edf93536027d26cf656100ea 169 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 47 66 1.5E-10 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 VAPA_1c52890 d54115f0edf93536027d26cf656100ea 169 Gene3D G3DSA:1.10.10.10 11 73 2.9E-21 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c52890 d54115f0edf93536027d26cf656100ea 169 Pfam PF13412 Winged helix-turn-helix DNA-binding 20 67 1.3E-16 T 12-10-2018 VAPA_1c52890 d54115f0edf93536027d26cf656100ea 169 Gene3D G3DSA:3.30.70.920 74 157 2.7E-19 T 12-10-2018 VAPA_1c52890 d54115f0edf93536027d26cf656100ea 169 ProSitePatterns PS00519 AsnC-type HTH domain signature. 38 64 - T 12-10-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site VAPA_1c52890 d54115f0edf93536027d26cf656100ea 169 SUPERFAMILY SSF46785 20 78 9.4E-15 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c52890 d54115f0edf93536027d26cf656100ea 169 SMART SM00344 20 129 2.6E-38 T 12-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 VAPA_1c52890 d54115f0edf93536027d26cf656100ea 169 SUPERFAMILY SSF54909 80 169 3.35E-19 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel VAPA_1c13250 8a1b9a59b42305d0ee5f79d21f2d2c4f 136 SUPERFAMILY SSF52172 2 125 3.7E-20 T 12-10-2018 IPR011006 CheY-like superfamily VAPA_1c13250 8a1b9a59b42305d0ee5f79d21f2d2c4f 136 Gene3D G3DSA:3.40.50.2300 1 133 5.4E-19 T 12-10-2018 VAPA_1c13250 8a1b9a59b42305d0ee5f79d21f2d2c4f 136 SMART SM00448 4 119 7.9E-8 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_1c13250 8a1b9a59b42305d0ee5f79d21f2d2c4f 136 Pfam PF00072 Response regulator receiver domain 7 117 2.5E-13 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_1c38130 945d102d7d56bee24891a3290a096d1f 578 SUPERFAMILY SSF52016 380 565 5.18E-59 T 12-10-2018 VAPA_1c38130 945d102d7d56bee24891a3290a096d1f 578 Pfam PF00920 Dehydratase family 45 560 9.2E-177 T 12-10-2018 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 VAPA_1c38130 945d102d7d56bee24891a3290a096d1f 578 Gene3D G3DSA:3.50.30.80 380 534 3.3E-49 T 12-10-2018 VAPA_1c38130 945d102d7d56bee24891a3290a096d1f 578 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 128 138 - T 12-10-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 VAPA_1c38130 945d102d7d56bee24891a3290a096d1f 578 SUPERFAMILY SSF143975 7 377 2.22E-122 T 12-10-2018 IPR037237 IlvD/EDD, N-terminal domain KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 VAPA_1c42320 b770a10c85dd20554bf7ee75958ab7ec 232 SUPERFAMILY SSF46785 88 168 7.48E-25 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c42320 b770a10c85dd20554bf7ee75958ab7ec 232 Hamap MF_01584 UPF0502 protein YceH [yceH]. 8 224 31.903 T 12-10-2018 IPR007432 Protein of unknown function DUF480 VAPA_1c42320 b770a10c85dd20554bf7ee75958ab7ec 232 Pfam PF04337 Protein of unknown function, DUF480 8 154 4.0E-56 T 12-10-2018 IPR007432 Protein of unknown function DUF480 VAPA_1c42320 b770a10c85dd20554bf7ee75958ab7ec 232 Gene3D G3DSA:1.10.10.10 92 171 5.4E-28 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c42320 b770a10c85dd20554bf7ee75958ab7ec 232 SUPERFAMILY SSF46785 5 85 6.53E-30 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c42320 b770a10c85dd20554bf7ee75958ab7ec 232 Gene3D G3DSA:1.10.10.10 1 91 3.2E-33 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c45490 53f9ef3d972f3ed2d7bff223b27b3d50 602 SUPERFAMILY SSF47384 203 285 4.71E-12 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 VAPA_1c45490 53f9ef3d972f3ed2d7bff223b27b3d50 602 Pfam PF00072 Response regulator receiver domain 474 590 6.9E-11 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_1c45490 53f9ef3d972f3ed2d7bff223b27b3d50 602 Pfam PF00512 His Kinase A (phospho-acceptor) domain 221 285 2.4E-9 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 VAPA_1c45490 53f9ef3d972f3ed2d7bff223b27b3d50 602 Gene3D G3DSA:3.40.50.2300 463 600 5.2E-15 T 12-10-2018 VAPA_1c45490 53f9ef3d972f3ed2d7bff223b27b3d50 602 Gene3D G3DSA:3.30.565.10 296 445 7.2E-39 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_1c45490 53f9ef3d972f3ed2d7bff223b27b3d50 602 SMART SM00388 220 285 2.1E-11 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 VAPA_1c45490 53f9ef3d972f3ed2d7bff223b27b3d50 602 Gene3D G3DSA:1.10.287.130 192 283 3.0E-12 T 12-10-2018 VAPA_1c45490 53f9ef3d972f3ed2d7bff223b27b3d50 602 SUPERFAMILY SSF55874 275 441 6.42E-42 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_1c45490 53f9ef3d972f3ed2d7bff223b27b3d50 602 SMART SM00387 329 440 1.9E-32 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase VAPA_1c45490 53f9ef3d972f3ed2d7bff223b27b3d50 602 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 330 438 1.2E-24 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase VAPA_1c45490 53f9ef3d972f3ed2d7bff223b27b3d50 602 SMART SM00448 472 591 4.9E-10 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_1c45490 53f9ef3d972f3ed2d7bff223b27b3d50 602 PRINTS PR00344 Bacterial sensor protein C-terminal signature 400 418 1.2E-14 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c45490 53f9ef3d972f3ed2d7bff223b27b3d50 602 PRINTS PR00344 Bacterial sensor protein C-terminal signature 365 379 1.2E-14 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c45490 53f9ef3d972f3ed2d7bff223b27b3d50 602 PRINTS PR00344 Bacterial sensor protein C-terminal signature 383 393 1.2E-14 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c45490 53f9ef3d972f3ed2d7bff223b27b3d50 602 PRINTS PR00344 Bacterial sensor protein C-terminal signature 424 437 1.2E-14 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c45490 53f9ef3d972f3ed2d7bff223b27b3d50 602 SUPERFAMILY SSF52172 472 595 7.68E-16 T 12-10-2018 IPR011006 CheY-like superfamily VAPA_2c00410 480e54f5865adaa0abb1433cdb5fa96a 456 Gene3D G3DSA:3.30.1330.120 278 403 1.8E-120 T 12-10-2018 VAPA_2c00410 480e54f5865adaa0abb1433cdb5fa96a 456 SUPERFAMILY SSF103378 14 448 1.7E-121 T 12-10-2018 IPR036148 MmgE/PrpD superfamily GO:0016829 VAPA_2c00410 480e54f5865adaa0abb1433cdb5fa96a 456 Pfam PF03972 MmgE/PrpD family 17 441 8.2E-129 T 12-10-2018 IPR005656 MmgE/PrpD GO:0016829 VAPA_2c00410 480e54f5865adaa0abb1433cdb5fa96a 456 Gene3D G3DSA:1.10.4100.10 38 419 1.8E-120 T 12-10-2018 VAPA_2c07370 77772c360cc485598cc81839f2e5bee5 312 Gene3D G3DSA:3.40.190.290 91 299 5.5E-35 T 12-10-2018 VAPA_2c07370 77772c360cc485598cc81839f2e5bee5 312 SUPERFAMILY SSF53850 88 293 5.25E-33 T 12-10-2018 VAPA_2c07370 77772c360cc485598cc81839f2e5bee5 312 SUPERFAMILY SSF46785 2 85 5.31E-22 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_2c07370 77772c360cc485598cc81839f2e5bee5 312 Gene3D G3DSA:1.10.10.10 1 88 2.9E-26 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_2c07370 77772c360cc485598cc81839f2e5bee5 312 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 3.5E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_2c07370 77772c360cc485598cc81839f2e5bee5 312 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 3.5E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_2c07370 77772c360cc485598cc81839f2e5bee5 312 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 3.5E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_2c07370 77772c360cc485598cc81839f2e5bee5 312 Pfam PF03466 LysR substrate binding domain 87 291 1.7E-34 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_2c07370 77772c360cc485598cc81839f2e5bee5 312 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 2.0E-20 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c12710 0c56a762a5defb1bad95429178da7a16 222 SUPERFAMILY SSF52540 2 220 4.48E-67 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c12710 0c56a762a5defb1bad95429178da7a16 222 SMART SM00382 31 219 8.7E-12 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c12710 0c56a762a5defb1bad95429178da7a16 222 Pfam PF00005 ABC transporter 22 170 1.7E-32 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c12710 0c56a762a5defb1bad95429178da7a16 222 ProSitePatterns PS00211 ABC transporters family signature. 143 157 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_1c12710 0c56a762a5defb1bad95429178da7a16 222 TIGRFAM TIGR02211 LolD_lipo_ex: lipoprotein releasing system, ATP-binding protein 2 220 2.0E-97 T 12-10-2018 IPR011924 Lipoprotein releasing system, ATP-binding protein GO:0005524|GO:0016020|GO:0044873 VAPA_1c12710 0c56a762a5defb1bad95429178da7a16 222 Gene3D G3DSA:3.40.50.300 1 222 3.4E-66 T 12-10-2018 VAPA_1c09370 9baec187f6d68c0989e6bfc822cba64f 347 PIRSF PIRSF017082 13 347 4.3E-68 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c09370 9baec187f6d68c0989e6bfc822cba64f 347 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 66 343 5.4E-72 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c09370 9baec187f6d68c0989e6bfc822cba64f 347 Gene3D G3DSA:3.40.190.10 145 272 3.5E-97 T 12-10-2018 VAPA_1c09370 9baec187f6d68c0989e6bfc822cba64f 347 SUPERFAMILY SSF53850 131 309 1.41E-9 T 12-10-2018 VAPA_1c09370 9baec187f6d68c0989e6bfc822cba64f 347 Gene3D G3DSA:3.40.190.150 47 337 3.5E-97 T 12-10-2018 VAPA_1c04900 5ed2f58ed918d8ce93cf999b85a8b2f8 147 Gene3D G3DSA:1.10.10.10 1 53 2.0E-18 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c04900 5ed2f58ed918d8ce93cf999b85a8b2f8 147 Pfam PF01037 Lrp/AsnC ligand binding domain 68 132 4.1E-12 T 12-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain VAPA_1c04900 5ed2f58ed918d8ce93cf999b85a8b2f8 147 Pfam PF13412 Winged helix-turn-helix DNA-binding 2 49 2.1E-14 T 12-10-2018 VAPA_1c04900 5ed2f58ed918d8ce93cf999b85a8b2f8 147 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 18 29 3.5E-13 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 VAPA_1c04900 5ed2f58ed918d8ce93cf999b85a8b2f8 147 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 29 48 3.5E-13 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 VAPA_1c04900 5ed2f58ed918d8ce93cf999b85a8b2f8 147 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 2 18 3.5E-13 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 VAPA_1c04900 5ed2f58ed918d8ce93cf999b85a8b2f8 147 SMART SM00344 2 108 6.0E-26 T 12-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 VAPA_1c04900 5ed2f58ed918d8ce93cf999b85a8b2f8 147 SUPERFAMILY SSF46785 1 62 2.62E-17 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c04900 5ed2f58ed918d8ce93cf999b85a8b2f8 147 Gene3D G3DSA:3.30.70.920 54 137 1.4E-18 T 12-10-2018 VAPA_1c04900 5ed2f58ed918d8ce93cf999b85a8b2f8 147 SUPERFAMILY SSF54909 64 133 4.16E-13 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel VAPA_1c19440 7a6f92be5166d274fb54ad0ac3ff7800 417 Gene3D G3DSA:1.20.1250.20 16 197 5.6E-28 T 12-10-2018 VAPA_1c19440 7a6f92be5166d274fb54ad0ac3ff7800 417 SUPERFAMILY SSF103473 12 406 3.14E-55 T 12-10-2018 IPR036259 MFS transporter superfamily VAPA_1c19440 7a6f92be5166d274fb54ad0ac3ff7800 417 Pfam PF07690 Major Facilitator Superfamily 26 287 7.0E-28 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 VAPA_1c19440 7a6f92be5166d274fb54ad0ac3ff7800 417 Gene3D G3DSA:1.20.1250.20 222 409 7.9E-17 T 12-10-2018 VAPA_1c40330 7e1506dc451b0ef1b3817e1b7e001436 548 SUPERFAMILY SSF56672 129 448 1.33E-53 T 12-10-2018 VAPA_1c40330 7e1506dc451b0ef1b3817e1b7e001436 548 TIGRFAM TIGR04416 group_II_RT_mat: group II intron reverse transcriptase/maturase 134 502 1.3E-104 T 12-10-2018 IPR030931 Group II intron reverse transcriptase/maturase VAPA_1c40330 7e1506dc451b0ef1b3817e1b7e001436 548 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 188 418 3.6E-41 T 12-10-2018 IPR000477 Reverse transcriptase domain VAPA_1c37860 6bff35e63c6e7eb52fd53fffb47797c6 269 SMART SM00062 43 263 2.8E-43 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF VAPA_1c37860 6bff35e63c6e7eb52fd53fffb47797c6 269 Gene3D G3DSA:3.40.190.10 40 255 2.1E-55 T 12-10-2018 VAPA_1c37860 6bff35e63c6e7eb52fd53fffb47797c6 269 Gene3D G3DSA:3.40.190.10 130 221 2.1E-55 T 12-10-2018 VAPA_1c37860 6bff35e63c6e7eb52fd53fffb47797c6 269 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 66 79 - T 12-10-2018 IPR018313 Solute-binding protein family 3, conserved site VAPA_1c37860 6bff35e63c6e7eb52fd53fffb47797c6 269 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 44 262 3.5E-52 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF VAPA_1c37860 6bff35e63c6e7eb52fd53fffb47797c6 269 SUPERFAMILY SSF53850 16 262 1.03E-55 T 12-10-2018 VAPA_1c40380 5b65164804761339a680454a3980ddac 329 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 53 325 1.4E-86 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c40380 5b65164804761339a680454a3980ddac 329 Gene3D G3DSA:3.40.190.150 34 319 1.8E-108 T 12-10-2018 VAPA_1c40380 5b65164804761339a680454a3980ddac 329 PIRSF PIRSF017082 2 329 1.5E-75 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c40380 5b65164804761339a680454a3980ddac 329 SUPERFAMILY SSF53850 118 283 2.17E-8 T 12-10-2018 VAPA_1c40380 5b65164804761339a680454a3980ddac 329 Gene3D G3DSA:3.40.190.10 132 254 1.8E-108 T 12-10-2018 VAPA_1c51300 c5938c9d96d41ac51db2f2f88a647476 153 Gene3D G3DSA:3.10.350.10 102 150 2.6E-13 T 12-10-2018 IPR036779 LysM domain superfamily VAPA_1c51300 c5938c9d96d41ac51db2f2f88a647476 153 SUPERFAMILY SSF54106 101 151 1.7E-7 T 12-10-2018 VAPA_1c51300 c5938c9d96d41ac51db2f2f88a647476 153 Pfam PF04972 BON domain 30 93 2.8E-11 T 12-10-2018 IPR007055 BON domain VAPA_1c51300 c5938c9d96d41ac51db2f2f88a647476 153 SMART SM00257 102 151 2.5E-12 T 12-10-2018 IPR018392 LysM domain VAPA_1c51300 c5938c9d96d41ac51db2f2f88a647476 153 Pfam PF01476 LysM domain 103 151 2.9E-12 T 12-10-2018 IPR018392 LysM domain VAPA_1c52410 e2fcb0a7d348214fab6e6b5763c175d6 37 TIGRFAM TIGR01022 rpmJ_bact: ribosomal protein bL36 1 37 9.7E-21 T 12-10-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 VAPA_1c52410 e2fcb0a7d348214fab6e6b5763c175d6 37 Hamap MF_00251 50S ribosomal protein L36 [rpmJ]. 1 37 16.868 T 12-10-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 VAPA_1c52410 e2fcb0a7d348214fab6e6b5763c175d6 37 Pfam PF00444 Ribosomal protein L36 1 37 3.7E-18 T 12-10-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 VAPA_1c52410 e2fcb0a7d348214fab6e6b5763c175d6 37 ProSitePatterns PS00828 Ribosomal protein L36 signature. 11 36 - T 12-10-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 VAPA_1c52410 e2fcb0a7d348214fab6e6b5763c175d6 37 SUPERFAMILY SSF57840 1 37 5.1E-16 T 12-10-2018 IPR035977 Ribosomal protein L36 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 VAPA_1c46640 356ade81239aecab3f1998b0d9c5d9cd 423 SUPERFAMILY SSF89796 4 423 5.1E-121 T 12-10-2018 IPR023606 CoA-transferase family III domain superfamily VAPA_1c46640 356ade81239aecab3f1998b0d9c5d9cd 423 Pfam PF02515 CoA-transferase family III 6 400 6.6E-92 T 12-10-2018 IPR003673 CoA-transferase family III GO:0003824 VAPA_1c46640 356ade81239aecab3f1998b0d9c5d9cd 423 Gene3D G3DSA:3.40.50.10540 5 414 3.3E-151 T 12-10-2018 IPR023606 CoA-transferase family III domain superfamily VAPA_1c46640 356ade81239aecab3f1998b0d9c5d9cd 423 TIGRFAM TIGR03253 oxalate_frc: formyl-CoA transferase 4 423 2.0E-216 T 12-10-2018 IPR017659 Formyl-CoA:oxalate CoA-transferase GO:0033608 MetaCyc: PWY-6695 VAPA_1c46640 356ade81239aecab3f1998b0d9c5d9cd 423 Hamap MF_00742 Formyl-CoA:oxalate CoA-transferase [frc]. 2 423 62.141 T 12-10-2018 IPR017659 Formyl-CoA:oxalate CoA-transferase GO:0033608 MetaCyc: PWY-6695 VAPA_1c46640 356ade81239aecab3f1998b0d9c5d9cd 423 Gene3D G3DSA:3.30.1540.10 250 346 3.3E-151 T 12-10-2018 VAPA_1c24260 b8e13c106b670bc96c6f2e5fb8074003 391 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 226 239 - T 12-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 VAPA_1c24260 b8e13c106b670bc96c6f2e5fb8074003 391 Gene3D G3DSA:3.40.640.10 11 384 3.1E-60 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 VAPA_1c24260 b8e13c106b670bc96c6f2e5fb8074003 391 SUPERFAMILY SSF53383 26 379 6.12E-76 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase VAPA_1c24260 b8e13c106b670bc96c6f2e5fb8074003 391 Pfam PF00155 Aminotransferase class I and II 33 372 6.2E-38 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 VAPA_1c24830 3274409a44be94edde4ea2dfd4608cf6 477 Pfam PF00171 Aldehyde dehydrogenase family 13 472 2.8E-153 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 VAPA_1c24830 3274409a44be94edde4ea2dfd4608cf6 477 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 273 284 - T 12-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 VAPA_1c24830 3274409a44be94edde4ea2dfd4608cf6 477 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 245 252 - T 12-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 VAPA_1c24830 3274409a44be94edde4ea2dfd4608cf6 477 Gene3D G3DSA:3.40.309.10 249 441 1.3E-169 T 12-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 VAPA_1c24830 3274409a44be94edde4ea2dfd4608cf6 477 SUPERFAMILY SSF53720 4 475 3.14E-150 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 VAPA_1c24830 3274409a44be94edde4ea2dfd4608cf6 477 Gene3D G3DSA:3.40.605.10 21 467 1.3E-169 T 12-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 VAPA_1c34150 90e244f230b21f873761203174546dde 292 Gene3D G3DSA:1.10.1040.10 163 291 2.9E-30 T 12-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 VAPA_1c34150 90e244f230b21f873761203174546dde 292 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 165 284 1.5E-24 T 12-10-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 VAPA_1c34150 90e244f230b21f873761203174546dde 292 Gene3D G3DSA:3.40.50.12340 88 162 5.2E-15 T 12-10-2018 VAPA_1c34150 90e244f230b21f873761203174546dde 292 SUPERFAMILY SSF48179 164 287 2.38E-26 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 VAPA_1c34150 90e244f230b21f873761203174546dde 292 SUPERFAMILY SSF51735 96 162 7.16E-12 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c34150 90e244f230b21f873761203174546dde 292 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 96 162 1.2E-11 T 12-10-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 VAPA_1c08240 842f68b2f744f145c2c899fcf7dd8be3 345 SUPERFAMILY SSF51735 3 336 2.83E-70 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c08240 842f68b2f744f145c2c899fcf7dd8be3 345 TIGRFAM TIGR01472 gmd: GDP-mannose 4,6-dehydratase 3 337 3.9E-140 T 12-10-2018 IPR006368 GDP-mannose 4,6-dehydratase GO:0008446|GO:0019673 KEGG: 00051+4.2.1.47|KEGG: 00520+4.2.1.47|MetaCyc: PWY-5738|MetaCyc: PWY-5739|MetaCyc: PWY-5740|MetaCyc: PWY-66|MetaCyc: PWY-7573|Reactome: R-HSA-6787639 VAPA_1c08240 842f68b2f744f145c2c899fcf7dd8be3 345 Gene3D G3DSA:3.90.25.10 188 336 3.2E-144 T 12-10-2018 VAPA_1c08240 842f68b2f744f145c2c899fcf7dd8be3 345 Hamap MF_00955 GDP-mannose 4,6-dehydratase [gmd]. 3 341 52.508 T 12-10-2018 IPR006368 GDP-mannose 4,6-dehydratase GO:0008446|GO:0019673 KEGG: 00051+4.2.1.47|KEGG: 00520+4.2.1.47|MetaCyc: PWY-5738|MetaCyc: PWY-5739|MetaCyc: PWY-5740|MetaCyc: PWY-66|MetaCyc: PWY-7573|Reactome: R-HSA-6787639 VAPA_1c08240 842f68b2f744f145c2c899fcf7dd8be3 345 Pfam PF16363 GDP-mannose 4,6 dehydratase 7 331 9.0E-134 T 12-10-2018 IPR016040 NAD(P)-binding domain VAPA_1c08240 842f68b2f744f145c2c899fcf7dd8be3 345 Gene3D G3DSA:3.40.50.720 5 322 3.2E-144 T 12-10-2018 VAPA_1c03930 8d5a2f685d51597712b9911f1408a2b0 540 SUPERFAMILY SSF52096 238 519 2.49E-75 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily VAPA_1c03930 8d5a2f685d51597712b9911f1408a2b0 540 Gene3D G3DSA:3.90.226.10 274 540 5.3E-85 T 12-10-2018 VAPA_1c03930 8d5a2f685d51597712b9911f1408a2b0 540 SUPERFAMILY SSF52096 40 266 1.69E-48 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily VAPA_1c03930 8d5a2f685d51597712b9911f1408a2b0 540 Gene3D G3DSA:3.90.226.10 1 273 8.9E-63 T 12-10-2018 VAPA_1c03930 8d5a2f685d51597712b9911f1408a2b0 540 Pfam PF01039 Carboxyl transferase domain 49 521 1.6E-115 T 12-10-2018 IPR034733 Acetyl-CoA carboxylase MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722|Reactome: R-HSA-196780 VAPA_2c02970 e28bd3e845437a00c3ac1a38a96cce53 308 SUPERFAMILY SSF46785 4 111 1.33E-21 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_2c02970 e28bd3e845437a00c3ac1a38a96cce53 308 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 62 1.4E-17 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_2c02970 e28bd3e845437a00c3ac1a38a96cce53 308 Gene3D G3DSA:3.40.190.10 162 267 5.3E-63 T 12-10-2018 VAPA_2c02970 e28bd3e845437a00c3ac1a38a96cce53 308 Pfam PF03466 LysR substrate binding domain 88 295 1.4E-41 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_2c02970 e28bd3e845437a00c3ac1a38a96cce53 308 Gene3D G3DSA:3.40.190.10 91 292 5.3E-63 T 12-10-2018 VAPA_2c02970 e28bd3e845437a00c3ac1a38a96cce53 308 SUPERFAMILY SSF53850 90 299 1.59E-42 T 12-10-2018 VAPA_2c02970 e28bd3e845437a00c3ac1a38a96cce53 308 Gene3D G3DSA:1.10.10.10 3 89 3.0E-26 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c07830 e714f38443bfdbeb85ee651438a049af 454 Gene3D G3DSA:1.20.1250.20 33 445 1.1E-55 T 12-10-2018 VAPA_1c07830 e714f38443bfdbeb85ee651438a049af 454 ProSitePatterns PS00216 Sugar transport proteins signature 1. 95 111 - T 12-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 VAPA_1c07830 e714f38443bfdbeb85ee651438a049af 454 ProSitePatterns PS00217 Sugar transport proteins signature 2. 145 170 - T 12-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 VAPA_1c07830 e714f38443bfdbeb85ee651438a049af 454 ProSitePatterns PS00216 Sugar transport proteins signature 1. 313 330 - T 12-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 VAPA_1c07830 e714f38443bfdbeb85ee651438a049af 454 SUPERFAMILY SSF103473 36 443 1.83E-61 T 12-10-2018 IPR036259 MFS transporter superfamily VAPA_1c07830 e714f38443bfdbeb85ee651438a049af 454 Pfam PF00083 Sugar (and other) transporter 37 404 2.4E-27 T 12-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 VAPA_1c03510 427380df6e3a050aca6216bd1082ea16 441 Pfam PF04209 homogentisate 1,2-dioxygenase 11 439 6.7E-199 T 12-10-2018 IPR005708 Homogentisate 1,2-dioxygenase GO:0004411|GO:0006559|GO:0006570|GO:0055114 KEGG: 00350+1.13.11.5|KEGG: 00643+1.13.11.5|Reactome: R-HSA-71182 VAPA_1c03510 427380df6e3a050aca6216bd1082ea16 441 SUPERFAMILY SSF51182 10 440 1.11E-160 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily VAPA_1c03510 427380df6e3a050aca6216bd1082ea16 441 Gene3D G3DSA:2.60.120.10 271 409 6.0E-65 T 12-10-2018 IPR014710 RmlC-like jelly roll fold VAPA_1c03510 427380df6e3a050aca6216bd1082ea16 441 TIGRFAM TIGR01015 hmgA: homogentisate 1,2-dioxygenase 10 439 1.1E-196 T 12-10-2018 IPR005708 Homogentisate 1,2-dioxygenase GO:0004411|GO:0006559|GO:0006570|GO:0055114 KEGG: 00350+1.13.11.5|KEGG: 00643+1.13.11.5|Reactome: R-HSA-71182 VAPA_2c07220 5ed358f829a4ffffdc2eec5f98a4e0ab 1049 SUPERFAMILY SSF82693 674 861 2.22E-24 T 12-10-2018 VAPA_2c07220 5ed358f829a4ffffdc2eec5f98a4e0ab 1049 Gene3D G3DSA:3.30.70.1320 134 333 0.0 T 12-10-2018 VAPA_2c07220 5ed358f829a4ffffdc2eec5f98a4e0ab 1049 SUPERFAMILY SSF82866 297 498 5.75E-51 T 12-10-2018 VAPA_2c07220 5ed358f829a4ffffdc2eec5f98a4e0ab 1049 PRINTS PR00702 Acriflavin resistance protein family signature 36 54 2.5E-106 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 VAPA_2c07220 5ed358f829a4ffffdc2eec5f98a4e0ab 1049 PRINTS PR00702 Acriflavin resistance protein family signature 471 494 2.5E-106 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 VAPA_2c07220 5ed358f829a4ffffdc2eec5f98a4e0ab 1049 PRINTS PR00702 Acriflavin resistance protein family signature 8 32 2.5E-106 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 VAPA_2c07220 5ed358f829a4ffffdc2eec5f98a4e0ab 1049 PRINTS PR00702 Acriflavin resistance protein family signature 392 416 2.5E-106 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 VAPA_2c07220 5ed358f829a4ffffdc2eec5f98a4e0ab 1049 PRINTS PR00702 Acriflavin resistance protein family signature 558 575 2.5E-106 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 VAPA_2c07220 5ed358f829a4ffffdc2eec5f98a4e0ab 1049 PRINTS PR00702 Acriflavin resistance protein family signature 625 639 2.5E-106 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 VAPA_2c07220 5ed358f829a4ffffdc2eec5f98a4e0ab 1049 PRINTS PR00702 Acriflavin resistance protein family signature 446 469 2.5E-106 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 VAPA_2c07220 5ed358f829a4ffffdc2eec5f98a4e0ab 1049 PRINTS PR00702 Acriflavin resistance protein family signature 364 385 2.5E-106 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 VAPA_2c07220 5ed358f829a4ffffdc2eec5f98a4e0ab 1049 PRINTS PR00702 Acriflavin resistance protein family signature 337 360 2.5E-106 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 VAPA_2c07220 5ed358f829a4ffffdc2eec5f98a4e0ab 1049 SUPERFAMILY SSF82693 38 131 8.2E-27 T 12-10-2018 VAPA_2c07220 5ed358f829a4ffffdc2eec5f98a4e0ab 1049 Gene3D G3DSA:3.30.70.1440 671 870 0.0 T 12-10-2018 VAPA_2c07220 5ed358f829a4ffffdc2eec5f98a4e0ab 1049 SUPERFAMILY SSF82693 136 331 1.62E-27 T 12-10-2018 VAPA_2c07220 5ed358f829a4ffffdc2eec5f98a4e0ab 1049 SUPERFAMILY SSF82693 571 671 8.37E-29 T 12-10-2018 VAPA_2c07220 5ed358f829a4ffffdc2eec5f98a4e0ab 1049 SUPERFAMILY SSF82866 836 1029 4.58E-41 T 12-10-2018 VAPA_2c07220 5ed358f829a4ffffdc2eec5f98a4e0ab 1049 SUPERFAMILY SSF82714 183 273 3.66E-20 T 12-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains VAPA_2c07220 5ed358f829a4ffffdc2eec5f98a4e0ab 1049 Gene3D G3DSA:3.30.70.1430 38 822 0.0 T 12-10-2018 VAPA_2c07220 5ed358f829a4ffffdc2eec5f98a4e0ab 1049 Gene3D G3DSA:3.30.70.1430 573 670 0.0 T 12-10-2018 VAPA_2c07220 5ed358f829a4ffffdc2eec5f98a4e0ab 1049 Gene3D G3DSA:3.30.2090.10 180 276 0.0 T 12-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains VAPA_2c07220 5ed358f829a4ffffdc2eec5f98a4e0ab 1049 TIGRFAM TIGR00915 2A0602: RND transporter, hydrophobe/amphiphile efflux-1 (HAE1) family 1 1046 0.0 T 12-10-2018 IPR004764 Hydrophobe/amphiphile efflux-1 HAE1 GO:0006855|GO:0015562|GO:0016021 VAPA_2c07220 5ed358f829a4ffffdc2eec5f98a4e0ab 1049 Gene3D G3DSA:1.20.1640.10 519 1027 0.0 T 12-10-2018 VAPA_2c07220 5ed358f829a4ffffdc2eec5f98a4e0ab 1049 Pfam PF00873 AcrB/AcrD/AcrF family 1 1030 0.0 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 VAPA_2c07220 5ed358f829a4ffffdc2eec5f98a4e0ab 1049 Gene3D G3DSA:1.20.1640.10 8 518 0.0 T 12-10-2018 VAPA_2c07220 5ed358f829a4ffffdc2eec5f98a4e0ab 1049 SUPERFAMILY SSF82714 726 806 3.79E-17 T 12-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains VAPA_2c07220 5ed358f829a4ffffdc2eec5f98a4e0ab 1049 Gene3D G3DSA:3.30.2090.10 723 814 0.0 T 12-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains VAPA_1c11400 0909c19db59e686bd0c74ebc8f166f0c 149 Pfam PF02566 OsmC-like protein 44 142 4.2E-14 T 12-10-2018 IPR003718 OsmC/Ohr family VAPA_1c11400 0909c19db59e686bd0c74ebc8f166f0c 149 SUPERFAMILY SSF82784 1 145 9.03E-35 T 12-10-2018 IPR036102 OsmC/Ohr superfamily VAPA_1c11400 0909c19db59e686bd0c74ebc8f166f0c 149 Gene3D G3DSA:3.30.300.20 13 147 1.3E-30 T 12-10-2018 IPR015946 K homology domain-like, alpha/beta VAPA_1c26840 9c57c0bf3c3ebc763d783089ca1c79cf 327 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 51 323 5.8E-79 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c26840 9c57c0bf3c3ebc763d783089ca1c79cf 327 SUPERFAMILY SSF53850 122 289 1.25E-6 T 12-10-2018 VAPA_1c26840 9c57c0bf3c3ebc763d783089ca1c79cf 327 Gene3D G3DSA:3.40.190.10 129 252 5.2E-108 T 12-10-2018 VAPA_1c26840 9c57c0bf3c3ebc763d783089ca1c79cf 327 PIRSF PIRSF017082 1 327 2.1E-74 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c26840 9c57c0bf3c3ebc763d783089ca1c79cf 327 Gene3D G3DSA:3.40.190.150 32 317 5.2E-108 T 12-10-2018 VAPA_1c40460 94dc500cae91116753a7a7e885658a95 223 Pfam PF13358 DDE superfamily endonuclease 32 181 2.3E-27 T 12-10-2018 IPR038717 Tc1-like transposase, DDE domain VAPA_1c10560 94dc500cae91116753a7a7e885658a95 223 Pfam PF13358 DDE superfamily endonuclease 32 181 2.3E-27 T 12-10-2018 IPR038717 Tc1-like transposase, DDE domain VAPA_1c54900 3bf9be1da50282e43750e4e726f72c68 152 SUPERFAMILY SSF140804 30 137 2.75E-32 T 12-10-2018 IPR027405 YidB-like VAPA_1c54900 3bf9be1da50282e43750e4e726f72c68 152 Gene3D G3DSA:1.10.10.690 1 150 2.5E-34 T 12-10-2018 IPR027405 YidB-like VAPA_1c54900 3bf9be1da50282e43750e4e726f72c68 152 Pfam PF06078 Bacterial protein of unknown function (DUF937) 3 124 2.5E-13 T 12-10-2018 IPR009282 Protein of unknown function DUF937 VAPA_2c02790 a80de6382c395ad0529e21878e65f39f 244 Pfam PF13183 4Fe-4S dicluster domain 152 222 2.5E-6 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain VAPA_2c02790 a80de6382c395ad0529e21878e65f39f 244 SUPERFAMILY SSF46548 110 236 6.1E-24 T 12-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 VAPA_2c02790 a80de6382c395ad0529e21878e65f39f 244 Gene3D G3DSA:1.10.1060.10 110 241 4.1E-27 T 12-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 VAPA_2c02790 a80de6382c395ad0529e21878e65f39f 244 SUPERFAMILY SSF54292 23 109 2.36E-24 T 12-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 VAPA_2c02790 a80de6382c395ad0529e21878e65f39f 244 TIGRFAM TIGR00384 dhsB: succinate dehydrogenase and fumarate reductase iron-sulfur protein 24 233 5.2E-53 T 12-10-2018 IPR004489 Succinate dehydrogenase/fumarate reductase iron-sulphur protein GO:0006099|GO:0016491|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 VAPA_2c02790 a80de6382c395ad0529e21878e65f39f 244 Pfam PF13085 2Fe-2S iron-sulfur cluster binding domain 21 114 3.0E-29 T 12-10-2018 IPR025192 Succinate dehydogenase/fumarate reductase N-terminal GO:0009055|GO:0051536 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 VAPA_2c02790 a80de6382c395ad0529e21878e65f39f 244 Gene3D G3DSA:3.10.20.30 8 109 6.9E-29 T 12-10-2018 IPR012675 Beta-grasp domain superfamily VAPA_2c02790 a80de6382c395ad0529e21878e65f39f 244 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 59 67 - T 12-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 VAPA_1c19580 5a551e1ee95d197903c952f3f661c933 574 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 399 548 9.2E-34 T 12-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 VAPA_1c19580 5a551e1ee95d197903c952f3f661c933 574 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 198 333 8.6E-31 T 12-10-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 VAPA_1c19580 5a551e1ee95d197903c952f3f661c933 574 SUPERFAMILY SSF52518 375 556 5.47E-49 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold VAPA_1c19580 5a551e1ee95d197903c952f3f661c933 574 SUPERFAMILY SSF52518 7 187 8.34E-49 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold VAPA_1c19580 5a551e1ee95d197903c952f3f661c933 574 Gene3D G3DSA:3.40.50.970 1 187 7.5E-56 T 12-10-2018 VAPA_1c19580 5a551e1ee95d197903c952f3f661c933 574 Gene3D G3DSA:3.40.50.1220 191 362 7.1E-39 T 12-10-2018 VAPA_1c19580 5a551e1ee95d197903c952f3f661c933 574 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 8 178 2.6E-49 T 12-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 VAPA_1c19580 5a551e1ee95d197903c952f3f661c933 574 Gene3D G3DSA:3.40.50.970 370 558 7.8E-50 T 12-10-2018 VAPA_1c19580 5a551e1ee95d197903c952f3f661c933 574 SUPERFAMILY SSF52467 162 360 2.57E-38 T 12-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily VAPA_1c04570 933c35cdc97ba62fb4da91ee34c9efd7 183 SUPERFAMILY SSF50249 3 183 2.71E-63 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold VAPA_1c04570 933c35cdc97ba62fb4da91ee34c9efd7 183 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 2 183 1.2E-52 T 12-10-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 VAPA_1c04570 933c35cdc97ba62fb4da91ee34c9efd7 183 Pfam PF00436 Single-strand binding protein family 4 108 5.2E-41 T 12-10-2018 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 VAPA_1c04570 933c35cdc97ba62fb4da91ee34c9efd7 183 Hamap MF_00984 Single-stranded DNA-binding protein. 4 112 37.874 T 12-10-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 VAPA_1c04570 933c35cdc97ba62fb4da91ee34c9efd7 183 Gene3D G3DSA:2.40.50.140 2 141 5.1E-48 T 12-10-2018 VAPA_1c43140 165d1584fb47a095bd3786f06de70b5d 286 TIGRFAM TIGR03818 MotA1: flagellar motor stator protein MotA 3 281 8.8E-118 T 12-10-2018 IPR022522 Flagellar motor stator, MotA VAPA_1c43140 165d1584fb47a095bd3786f06de70b5d 286 Pfam PF01618 MotA/TolQ/ExbB proton channel family 126 236 1.6E-9 T 12-10-2018 IPR002898 MotA/TolQ/ExbB proton channel VAPA_1c43140 165d1584fb47a095bd3786f06de70b5d 286 ProSitePatterns PS01307 Flagellar motor protein motA family signature. 205 222 - T 12-10-2018 IPR000540 Flagellar motor protein MotA, conserved site VAPA_1c38210 9131183d859abfccc370f6d73de00e54 167 Pfam PF12802 MarR family 40 97 4.3E-10 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 VAPA_1c38210 9131183d859abfccc370f6d73de00e54 167 Gene3D G3DSA:1.10.10.10 14 151 2.0E-25 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c38210 9131183d859abfccc370f6d73de00e54 167 SMART SM00347 35 134 6.2E-4 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 VAPA_1c38210 9131183d859abfccc370f6d73de00e54 167 SUPERFAMILY SSF46785 13 149 1.82E-25 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c11570 6137acdb9d7ed5205c1ae0727a8bac53 225 Gene3D G3DSA:2.40.128.20 63 225 1.2E-45 T 12-10-2018 IPR012674 Calycin VAPA_1c11570 6137acdb9d7ed5205c1ae0727a8bac53 225 PIRSF PIRSF036893 29 224 5.5E-46 T 12-10-2018 IPR022271 Lipocalin, ApoD type VAPA_1c11570 6137acdb9d7ed5205c1ae0727a8bac53 225 SUPERFAMILY SSF50814 67 223 1.25E-38 T 12-10-2018 IPR012674 Calycin VAPA_1c11570 6137acdb9d7ed5205c1ae0727a8bac53 225 Pfam PF08212 Lipocalin-like domain 75 221 1.7E-42 T 12-10-2018 IPR000566 Lipocalin/cytosolic fatty-acid binding domain VAPA_1c45530 c76b4967c5d4ac8baa3c32f803e63b3b 279 SUPERFAMILY SSF48371 83 277 1.86E-30 T 12-10-2018 IPR016024 Armadillo-type fold VAPA_1c45530 c76b4967c5d4ac8baa3c32f803e63b3b 279 Pfam PF08713 DNA alkylation repair enzyme 157 254 3.7E-5 T 12-10-2018 IPR014825 DNA alkylation repair enzyme VAPA_1c45530 c76b4967c5d4ac8baa3c32f803e63b3b 279 Gene3D G3DSA:1.25.40.290 154 277 3.0E-30 T 12-10-2018 VAPA_2c04890 7703fac522b90d943cd32cdafa3e8885 814 SUPERFAMILY SSF51621 471 803 1.2E-91 T 12-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 VAPA_2c04890 7703fac522b90d943cd32cdafa3e8885 814 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 489 794 2.2E-55 T 12-10-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 VAPA_2c04890 7703fac522b90d943cd32cdafa3e8885 814 Gene3D G3DSA:3.50.30.10 370 485 4.4E-37 T 12-10-2018 VAPA_2c04890 7703fac522b90d943cd32cdafa3e8885 814 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 703 721 - T 12-10-2018 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 VAPA_2c04890 7703fac522b90d943cd32cdafa3e8885 814 Gene3D G3DSA:3.20.20.60 487 796 4.1E-95 T 12-10-2018 VAPA_2c04890 7703fac522b90d943cd32cdafa3e8885 814 SUPERFAMILY SSF56059 5 392 1.05E-99 T 12-10-2018 VAPA_2c04890 7703fac522b90d943cd32cdafa3e8885 814 PIRSF PIRSF000854 2 803 0.0 T 12-10-2018 IPR006319 Phosphoenolpyruvate synthase GO:0006090|GO:0008986 KEGG: 00620+2.7.9.2|KEGG: 00680+2.7.9.2|KEGG: 00720+2.7.9.2|MetaCyc: PWY-5484|MetaCyc: PWY-6142 VAPA_2c04890 7703fac522b90d943cd32cdafa3e8885 814 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 20 350 7.9E-108 T 12-10-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 VAPA_2c04890 7703fac522b90d943cd32cdafa3e8885 814 Gene3D G3DSA:3.30.1490.20 4 196 4.3E-68 T 12-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 VAPA_2c04890 7703fac522b90d943cd32cdafa3e8885 814 SUPERFAMILY SSF52009 357 475 6.02E-32 T 12-10-2018 IPR036637 Phosphohistidine domain superfamily GO:0016310|GO:0016772 VAPA_2c04890 7703fac522b90d943cd32cdafa3e8885 814 Gene3D G3DSA:3.30.470.20 197 361 4.7E-51 T 12-10-2018 VAPA_2c04890 7703fac522b90d943cd32cdafa3e8885 814 Pfam PF00391 PEP-utilising enzyme, mobile domain 392 463 2.3E-25 T 12-10-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 VAPA_2c04890 7703fac522b90d943cd32cdafa3e8885 814 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 422 433 - T 12-10-2018 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 VAPA_2c04890 7703fac522b90d943cd32cdafa3e8885 814 TIGRFAM TIGR01418 PEP_synth: phosphoenolpyruvate synthase 7 799 0.0 T 12-10-2018 IPR006319 Phosphoenolpyruvate synthase GO:0006090|GO:0008986 KEGG: 00620+2.7.9.2|KEGG: 00680+2.7.9.2|KEGG: 00720+2.7.9.2|MetaCyc: PWY-5484|MetaCyc: PWY-6142 VAPA_1c27340 b7b80fd03695ba9d47351d8b914cabfe 209 SUPERFAMILY SSF46626 23 204 6.36E-27 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 VAPA_1c27340 b7b80fd03695ba9d47351d8b914cabfe 209 Gene3D G3DSA:1.10.760.10 50 209 1.0E-69 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 VAPA_1c27340 b7b80fd03695ba9d47351d8b914cabfe 209 Pfam PF02433 Cytochrome C oxidase, mono-heme subunit/FixO 13 189 1.7E-84 T 12-10-2018 IPR003468 Cytochrome c oxidase, monohaem subunit/FixO VAPA_1c27340 b7b80fd03695ba9d47351d8b914cabfe 209 TIGRFAM TIGR00781 ccoO: cytochrome c oxidase, cbb3-type, subunit II 15 189 1.1E-88 T 12-10-2018 IPR003468 Cytochrome c oxidase, monohaem subunit/FixO VAPA_1c11130 404eebee04331f48b3aa5959348b1328 760 Gene3D G3DSA:3.40.50.300 482 740 2.8E-93 T 12-10-2018 VAPA_1c11130 404eebee04331f48b3aa5959348b1328 760 Gene3D G3DSA:1.20.1560.10 139 477 1.9E-85 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 VAPA_1c11130 404eebee04331f48b3aa5959348b1328 760 SUPERFAMILY SSF52540 481 725 2.17E-92 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c11130 404eebee04331f48b3aa5959348b1328 760 SMART SM00382 515 701 1.7E-20 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c11130 404eebee04331f48b3aa5959348b1328 760 SUPERFAMILY SSF90123 156 470 1.44E-75 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 VAPA_1c11130 404eebee04331f48b3aa5959348b1328 760 Pfam PF00664 ABC transporter transmembrane region 168 441 2.6E-44 T 12-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 VAPA_1c11130 404eebee04331f48b3aa5959348b1328 760 ProSitePatterns PS00211 ABC transporters family signature. 627 641 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_1c11130 404eebee04331f48b3aa5959348b1328 760 Pfam PF00005 ABC transporter 507 655 1.0E-32 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c54010 9624b3c8029bf9f9f1d1eb6d7ebe10ba 307 TIGRFAM TIGR01851 argC_other: N-acetyl-gamma-glutamyl-phosphate reductase 2 307 1.1E-117 T 12-10-2018 IPR010136 N-acetyl-gamma-glutamyl-phosphate reductase, type 2 GO:0003942|GO:0005737|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 VAPA_1c54010 9624b3c8029bf9f9f1d1eb6d7ebe10ba 307 SUPERFAMILY SSF55347 118 288 2.13E-33 T 12-10-2018 VAPA_1c54010 9624b3c8029bf9f9f1d1eb6d7ebe10ba 307 Gene3D G3DSA:3.40.50.720 1 121 3.5E-7 T 12-10-2018 VAPA_1c54010 9624b3c8029bf9f9f1d1eb6d7ebe10ba 307 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 42 103 1.2E-5 T 12-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 VAPA_1c54010 9624b3c8029bf9f9f1d1eb6d7ebe10ba 307 SMART SM00859 3 107 5.0E-17 T 12-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 VAPA_1c54010 9624b3c8029bf9f9f1d1eb6d7ebe10ba 307 Hamap MF_01110 N-acetyl-gamma-glutamyl-phosphate reductase [argC]. 1 307 50.63 T 12-10-2018 IPR010136 N-acetyl-gamma-glutamyl-phosphate reductase, type 2 GO:0003942|GO:0005737|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 VAPA_1c54010 9624b3c8029bf9f9f1d1eb6d7ebe10ba 307 SUPERFAMILY SSF51735 1 139 3.43E-29 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c54010 9624b3c8029bf9f9f1d1eb6d7ebe10ba 307 Gene3D G3DSA:3.30.360.10 122 292 2.5E-33 T 12-10-2018 VAPA_1c05970 88f94f53076e80a8986ad18ce625885c 538 Pfam PF03562 MltA specific insert domain 94 319 1.8E-46 T 12-10-2018 IPR005300 Lytic transglycosylase MltA, domain B GO:0004553 VAPA_1c05970 88f94f53076e80a8986ad18ce625885c 538 SUPERFAMILY SSF50685 81 319 8.72E-53 T 12-10-2018 IPR036908 RlpA-like domain superfamily VAPA_1c05970 88f94f53076e80a8986ad18ce625885c 538 SUPERFAMILY SSF50685 395 504 1.36E-42 T 12-10-2018 IPR036908 RlpA-like domain superfamily VAPA_1c05970 88f94f53076e80a8986ad18ce625885c 538 Gene3D G3DSA:2.40.240.50 227 340 2.0E-21 T 12-10-2018 VAPA_1c05970 88f94f53076e80a8986ad18ce625885c 538 Gene3D G3DSA:2.40.40.10 395 512 2.2E-37 T 12-10-2018 IPR036908 RlpA-like domain superfamily VAPA_1c05970 88f94f53076e80a8986ad18ce625885c 538 Gene3D G3DSA:2.40.40.10 60 181 2.2E-27 T 12-10-2018 IPR036908 RlpA-like domain superfamily VAPA_1c05970 88f94f53076e80a8986ad18ce625885c 538 SMART SM00925 169 403 7.1E-18 T 12-10-2018 IPR005300 Lytic transglycosylase MltA, domain B GO:0004553 VAPA_1c05970 88f94f53076e80a8986ad18ce625885c 538 Pfam PF06725 3D domain 424 497 1.2E-20 T 12-10-2018 IPR010611 3D domain GO:0004553|GO:0009254|GO:0019867 VAPA_1c02970 43be3c673422c4ed10550c2deab3bab2 486 Gene3D G3DSA:3.40.309.10 246 442 5.3E-178 T 12-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 VAPA_1c02970 43be3c673422c4ed10550c2deab3bab2 486 Gene3D G3DSA:3.40.605.10 8 470 5.3E-178 T 12-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 VAPA_1c02970 43be3c673422c4ed10550c2deab3bab2 486 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 269 280 - T 12-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 VAPA_1c02970 43be3c673422c4ed10550c2deab3bab2 486 Pfam PF00171 Aldehyde dehydrogenase family 16 472 1.7E-173 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 VAPA_1c02970 43be3c673422c4ed10550c2deab3bab2 486 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 241 248 - T 12-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 VAPA_1c02970 43be3c673422c4ed10550c2deab3bab2 486 TIGRFAM TIGR02299 HpaE: 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase 3 486 2.6E-243 T 12-10-2018 IPR011985 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase GO:0018480|GO:1901023 VAPA_1c02970 43be3c673422c4ed10550c2deab3bab2 486 SUPERFAMILY SSF53720 2 478 4.97E-165 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 VAPA_1c08690 43122bf0b1a213b6676bb2d0c01fc43b 252 Pfam PF00106 short chain dehydrogenase 11 198 4.0E-58 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c08690 43122bf0b1a213b6676bb2d0c01fc43b 252 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 147 175 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 VAPA_1c08690 43122bf0b1a213b6676bb2d0c01fc43b 252 SUPERFAMILY SSF51735 6 237 7.23E-69 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c08690 43122bf0b1a213b6676bb2d0c01fc43b 252 PIRSF PIRSF000126 1 244 6.4E-51 T 12-10-2018 VAPA_1c08690 43122bf0b1a213b6676bb2d0c01fc43b 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 181 198 2.1E-31 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c08690 43122bf0b1a213b6676bb2d0c01fc43b 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 160 179 2.1E-31 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c08690 43122bf0b1a213b6676bb2d0c01fc43b 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 133 149 2.1E-31 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c08690 43122bf0b1a213b6676bb2d0c01fc43b 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 12 29 2.1E-31 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c08690 43122bf0b1a213b6676bb2d0c01fc43b 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 86 97 2.1E-31 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c08690 43122bf0b1a213b6676bb2d0c01fc43b 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 86 97 6.8E-12 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c08690 43122bf0b1a213b6676bb2d0c01fc43b 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 139 147 6.8E-12 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c08690 43122bf0b1a213b6676bb2d0c01fc43b 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 160 179 6.8E-12 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c08690 43122bf0b1a213b6676bb2d0c01fc43b 252 Gene3D G3DSA:3.40.50.720 3 247 1.5E-72 T 12-10-2018 VAPA_1c08690 43122bf0b1a213b6676bb2d0c01fc43b 252 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 11 196 0.0014 T 12-10-2018 VAPA_1c04040 2fc83c5caffffe128a916fb438d83267 106 TIGRFAM TIGR02610 PHA_gran_rgn: putative polyhydroxyalkanoic acid system protein 3 93 2.8E-17 T 12-10-2018 IPR013433 Putative polyhydroxyalkanoic acid system protein VAPA_1c04040 2fc83c5caffffe128a916fb438d83267 106 Pfam PF09650 Putative polyhydroxyalkanoic acid system protein (PHA_gran_rgn) 4 94 3.5E-27 T 12-10-2018 IPR013433 Putative polyhydroxyalkanoic acid system protein VAPA_1c05600 191278a2f24faed71d1a73e7d1c595e4 260 Pfam PF03695 Uncharacterised protein family (UPF0149) 24 225 4.3E-28 T 12-10-2018 IPR011978 Uncharacterised protein family UPF0149 VAPA_1c05600 191278a2f24faed71d1a73e7d1c595e4 260 Gene3D G3DSA:3.10.450.50 214 260 2.1E-9 T 12-10-2018 VAPA_1c05600 191278a2f24faed71d1a73e7d1c595e4 260 SUPERFAMILY SSF101327 23 176 3.01E-5 T 12-10-2018 IPR036255 YgfB-like superfamily VAPA_1c05600 191278a2f24faed71d1a73e7d1c595e4 260 SUPERFAMILY SSF103642 240 259 2.45E-8 T 12-10-2018 VAPA_1c05600 191278a2f24faed71d1a73e7d1c595e4 260 Pfam PF02810 SEC-C motif 242 259 2.0E-11 T 12-10-2018 IPR004027 SEC-C motif VAPA_1c22530 0f1891429b3233cea1afc83baa4b6a08 246 SUPERFAMILY SSF53639 9 216 2.35E-55 T 12-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily VAPA_1c22530 0f1891429b3233cea1afc83baa4b6a08 246 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 15 197 1.1E-43 T 12-10-2018 IPR001303 Class II aldolase/adducin N-terminal VAPA_1c22530 0f1891429b3233cea1afc83baa4b6a08 246 Gene3D G3DSA:3.40.225.10 1 242 2.5E-65 T 12-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily VAPA_1c22530 0f1891429b3233cea1afc83baa4b6a08 246 SMART SM01007 14 197 3.9E-57 T 12-10-2018 IPR001303 Class II aldolase/adducin N-terminal VAPA_1c48290 31cee8913721a50efb8f62df40f089ff 130 SUPERFAMILY SSF54211 7 130 2.92E-44 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold VAPA_1c48290 31cee8913721a50efb8f62df40f089ff 130 Gene3D G3DSA:3.30.230.10 4 130 1.9E-47 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup VAPA_1c48290 31cee8913721a50efb8f62df40f089ff 130 Hamap MF_00532_B 30S ribosomal protein S9 [rpsI]. 1 130 30.033 T 12-10-2018 IPR023035 Ribosomal protein S9, bacterial/plastid VAPA_1c48290 31cee8913721a50efb8f62df40f089ff 130 ProSitePatterns PS00360 Ribosomal protein S9 signature. 69 87 - T 12-10-2018 IPR020574 Ribosomal protein S9, conserved site GO:0003735|GO:0005840|GO:0006412 VAPA_1c48290 31cee8913721a50efb8f62df40f089ff 130 Pfam PF00380 Ribosomal protein S9/S16 10 130 1.2E-42 T 12-10-2018 IPR000754 Ribosomal protein S9 GO:0003735|GO:0005840|GO:0006412 VAPA_2c05910 eb2a45ae69b7703d8850a8b86ace3540 122 SUPERFAMILY SSF75169 8 121 2.52E-17 T 12-10-2018 IPR027396 DsrEFH-like VAPA_2c05910 eb2a45ae69b7703d8850a8b86ace3540 122 Gene3D G3DSA:3.40.1260.10 1 122 2.4E-24 T 12-10-2018 IPR027396 DsrEFH-like VAPA_2c05910 eb2a45ae69b7703d8850a8b86ace3540 122 Pfam PF02635 DsrE/DsrF-like family 9 122 7.7E-15 T 12-10-2018 IPR003787 Sulphur relay, DsrE/F-like protein VAPA_1c44130 2aac147ae7c3deafe884eaae59002e4b 800 Gene3D G3DSA:3.10.20.310 352 428 3.3E-23 T 12-10-2018 VAPA_1c44130 2aac147ae7c3deafe884eaae59002e4b 800 Pfam PF07244 Surface antigen variable number repeat 272 344 1.1E-8 T 12-10-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 VAPA_1c44130 2aac147ae7c3deafe884eaae59002e4b 800 Pfam PF07244 Surface antigen variable number repeat 352 425 1.6E-11 T 12-10-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 VAPA_1c44130 2aac147ae7c3deafe884eaae59002e4b 800 Pfam PF07244 Surface antigen variable number repeat 29 94 2.2E-4 T 12-10-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 VAPA_1c44130 2aac147ae7c3deafe884eaae59002e4b 800 Pfam PF07244 Surface antigen variable number repeat 180 267 3.8E-12 T 12-10-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 VAPA_1c44130 2aac147ae7c3deafe884eaae59002e4b 800 Pfam PF07244 Surface antigen variable number repeat 97 176 3.8E-12 T 12-10-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 VAPA_1c44130 2aac147ae7c3deafe884eaae59002e4b 800 Gene3D G3DSA:3.10.20.310 96 176 1.3E-15 T 12-10-2018 VAPA_1c44130 2aac147ae7c3deafe884eaae59002e4b 800 PIRSF PIRSF006076 1 800 7.2E-232 T 12-10-2018 IPR023707 Outer membrane protein assembly factor BamA GO:0071709 VAPA_1c44130 2aac147ae7c3deafe884eaae59002e4b 800 Gene3D G3DSA:3.10.20.310 272 347 6.6E-13 T 12-10-2018 VAPA_1c44130 2aac147ae7c3deafe884eaae59002e4b 800 Pfam PF01103 Surface antigen 452 800 1.9E-70 T 12-10-2018 IPR000184 Bacterial surface antigen (D15) GO:0019867 Reactome: R-HSA-1268020|Reactome: R-HSA-8949613 VAPA_1c44130 2aac147ae7c3deafe884eaae59002e4b 800 Gene3D G3DSA:3.10.20.310 179 270 2.3E-20 T 12-10-2018 VAPA_1c44130 2aac147ae7c3deafe884eaae59002e4b 800 TIGRFAM TIGR03303 OM_YaeT: outer membrane protein assembly complex, YaeT protein 28 800 2.3E-245 T 12-10-2018 IPR023707 Outer membrane protein assembly factor BamA GO:0071709 VAPA_1c44130 2aac147ae7c3deafe884eaae59002e4b 800 Gene3D G3DSA:3.10.20.310 22 95 1.6E-18 T 12-10-2018 VAPA_1c44130 2aac147ae7c3deafe884eaae59002e4b 800 Gene3D G3DSA:2.40.160.50 429 800 2.2E-97 T 12-10-2018 VAPA_1c44130 2aac147ae7c3deafe884eaae59002e4b 800 Hamap MF_01430 Outer membrane protein assembly factor BamA [bamA]. 5 800 24.024 T 12-10-2018 IPR023707 Outer membrane protein assembly factor BamA GO:0071709 VAPA_1c33820 5e8bcfdade3fb5c57201df0759844e9a 532 Pfam PF10518 TAT (twin-arginine translocation) pathway signal sequence 1 23 1.8E-5 T 12-10-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal VAPA_1c33820 5e8bcfdade3fb5c57201df0759844e9a 532 Pfam PF04349 Periplasmic glucan biosynthesis protein, MdoG 40 529 6.3E-184 T 12-10-2018 IPR007444 Glucan biosynthesis, periplasmic, MdoG C-terminal GO:0016051|GO:0042597 VAPA_1c33820 5e8bcfdade3fb5c57201df0759844e9a 532 SUPERFAMILY SSF81296 422 531 5.18E-28 T 12-10-2018 IPR014756 Immunoglobulin E-set VAPA_1c33820 5e8bcfdade3fb5c57201df0759844e9a 532 SUPERFAMILY SSF74650 40 422 1.95E-143 T 12-10-2018 IPR011013 Galactose mutarotase-like domain superfamily GO:0003824|GO:0005975|GO:0030246 VAPA_1c33820 5e8bcfdade3fb5c57201df0759844e9a 532 PIRSF PIRSF006281 3 532 8.5E-182 T 12-10-2018 IPR014438 Glucan biosynthesis protein MdoG/MdoD VAPA_1c33820 5e8bcfdade3fb5c57201df0759844e9a 532 Gene3D G3DSA:2.60.40.10 427 532 2.6E-13 T 12-10-2018 IPR013783 Immunoglobulin-like fold VAPA_1c33820 5e8bcfdade3fb5c57201df0759844e9a 532 Gene3D G3DSA:2.70.98.10 39 422 5.3E-149 T 12-10-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 VAPA_1c33820 5e8bcfdade3fb5c57201df0759844e9a 532 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 2 28 0.001 T 12-10-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal VAPA_1c44180 24f1da3c42e1b2c491a110dfd4bd38bd 529 SMART SM00387 409 525 2.9E-31 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase VAPA_1c44180 24f1da3c42e1b2c491a110dfd4bd38bd 529 Gene3D G3DSA:3.30.565.10 371 528 1.1E-33 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_1c44180 24f1da3c42e1b2c491a110dfd4bd38bd 529 SMART SM00388 296 360 8.5E-11 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 VAPA_1c44180 24f1da3c42e1b2c491a110dfd4bd38bd 529 Pfam PF00512 His Kinase A (phospho-acceptor) domain 296 353 4.7E-11 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 VAPA_1c44180 24f1da3c42e1b2c491a110dfd4bd38bd 529 SUPERFAMILY SSF55874 361 523 4.19E-32 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_1c44180 24f1da3c42e1b2c491a110dfd4bd38bd 529 SUPERFAMILY SSF158472 243 291 1.06E-9 T 12-10-2018 VAPA_1c44180 24f1da3c42e1b2c491a110dfd4bd38bd 529 SUPERFAMILY SSF47384 280 356 6.47E-13 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 VAPA_1c44180 24f1da3c42e1b2c491a110dfd4bd38bd 529 SMART SM00304 243 295 1.6E-15 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 VAPA_1c44180 24f1da3c42e1b2c491a110dfd4bd38bd 529 Gene3D G3DSA:1.10.287.130 241 354 9.6E-26 T 12-10-2018 VAPA_1c44180 24f1da3c42e1b2c491a110dfd4bd38bd 529 PRINTS PR00344 Bacterial sensor protein C-terminal signature 468 478 2.9E-10 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c44180 24f1da3c42e1b2c491a110dfd4bd38bd 529 PRINTS PR00344 Bacterial sensor protein C-terminal signature 509 522 2.9E-10 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c44180 24f1da3c42e1b2c491a110dfd4bd38bd 529 PRINTS PR00344 Bacterial sensor protein C-terminal signature 485 503 2.9E-10 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c44180 24f1da3c42e1b2c491a110dfd4bd38bd 529 PRINTS PR00344 Bacterial sensor protein C-terminal signature 450 464 2.9E-10 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c44180 24f1da3c42e1b2c491a110dfd4bd38bd 529 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 409 524 4.2E-19 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase VAPA_1c44180 24f1da3c42e1b2c491a110dfd4bd38bd 529 Pfam PF00672 HAMP domain 243 291 9.1E-13 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 VAPA_1c06090 1c18eff688f450aa3266780c4ab9f441 864 SUPERFAMILY SSF141571 661 835 2.75E-35 T 12-10-2018 VAPA_1c06090 1c18eff688f450aa3266780c4ab9f441 864 Gene3D G3DSA:2.160.20.100 655 790 8.5E-29 T 12-10-2018 VAPA_1c06090 1c18eff688f450aa3266780c4ab9f441 864 Pfam PF00805 Pentapeptide repeats (8 copies) 545 567 0.009 T 12-10-2018 IPR001646 Pentapeptide repeat VAPA_1c06090 1c18eff688f450aa3266780c4ab9f441 864 Pfam PF00805 Pentapeptide repeats (8 copies) 608 645 0.001 T 12-10-2018 IPR001646 Pentapeptide repeat VAPA_1c06090 1c18eff688f450aa3266780c4ab9f441 864 Pfam PF00805 Pentapeptide repeats (8 copies) 799 838 1.1E-9 T 12-10-2018 IPR001646 Pentapeptide repeat VAPA_1c06090 1c18eff688f450aa3266780c4ab9f441 864 Pfam PF00805 Pentapeptide repeats (8 copies) 713 750 2.9E-5 T 12-10-2018 IPR001646 Pentapeptide repeat VAPA_1c06090 1c18eff688f450aa3266780c4ab9f441 864 Pfam PF00805 Pentapeptide repeats (8 copies) 755 791 1.1E-4 T 12-10-2018 IPR001646 Pentapeptide repeat VAPA_1c06090 1c18eff688f450aa3266780c4ab9f441 864 Pfam PF00805 Pentapeptide repeats (8 copies) 570 605 1.1E-7 T 12-10-2018 IPR001646 Pentapeptide repeat VAPA_1c06090 1c18eff688f450aa3266780c4ab9f441 864 Gene3D G3DSA:2.160.20.80 529 654 9.6E-24 T 12-10-2018 VAPA_1c06090 1c18eff688f450aa3266780c4ab9f441 864 Pfam PF09937 Uncharacterized protein conserved in bacteria (DUF2169) 41 292 3.1E-66 T 12-10-2018 IPR018683 Domain of unknown function DUF2169 VAPA_1c06090 1c18eff688f450aa3266780c4ab9f441 864 Gene3D G3DSA:2.160.20.100 791 853 1.3E-10 T 12-10-2018 VAPA_1c06090 1c18eff688f450aa3266780c4ab9f441 864 SUPERFAMILY SSF141571 545 689 4.97E-30 T 12-10-2018 VAPA_1c22420 6e1c5f0d67385bd00181c8db0952eef6 262 SUPERFAMILY SSF51735 5 247 2.3E-68 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c22420 6e1c5f0d67385bd00181c8db0952eef6 262 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 245 5.8E-57 T 12-10-2018 VAPA_1c22420 6e1c5f0d67385bd00181c8db0952eef6 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 124 140 1.5E-36 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c22420 6e1c5f0d67385bd00181c8db0952eef6 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 171 188 1.5E-36 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c22420 6e1c5f0d67385bd00181c8db0952eef6 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 150 169 1.5E-36 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c22420 6e1c5f0d67385bd00181c8db0952eef6 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 1.5E-36 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c22420 6e1c5f0d67385bd00181c8db0952eef6 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 208 228 1.5E-36 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c22420 6e1c5f0d67385bd00181c8db0952eef6 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 1.5E-36 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c22420 6e1c5f0d67385bd00181c8db0952eef6 262 Gene3D G3DSA:3.40.50.720 1 256 1.8E-69 T 12-10-2018 VAPA_1c22420 6e1c5f0d67385bd00181c8db0952eef6 262 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 137 165 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 VAPA_1c22420 6e1c5f0d67385bd00181c8db0952eef6 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 79 90 2.8E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c22420 6e1c5f0d67385bd00181c8db0952eef6 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 130 138 2.8E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c22420 6e1c5f0d67385bd00181c8db0952eef6 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 150 169 2.8E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c25100 0aab3ed77c9ea824665fef350d832004 338 SUPERFAMILY SSF51735 1 182 4.31E-75 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c25100 0aab3ed77c9ea824665fef350d832004 338 SUPERFAMILY SSF48179 183 333 9.18E-72 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 VAPA_1c25100 0aab3ed77c9ea824665fef350d832004 338 PIRSF PIRSF000116 201 333 9.3E-16 T 12-10-2018 IPR014359 Ketol-acid reductoisomerase, prokaryotic GO:0004455|GO:0009082|GO:0050661|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 VAPA_1c25100 0aab3ed77c9ea824665fef350d832004 338 PIRSF PIRSF000116 3 204 2.1E-44 T 12-10-2018 IPR014359 Ketol-acid reductoisomerase, prokaryotic GO:0004455|GO:0009082|GO:0050661|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 VAPA_1c25100 0aab3ed77c9ea824665fef350d832004 338 Gene3D G3DSA:3.40.50.720 1 181 2.1E-77 T 12-10-2018 VAPA_1c25100 0aab3ed77c9ea824665fef350d832004 338 Pfam PF01450 Acetohydroxy acid isomeroreductase, catalytic domain 183 326 2.9E-65 T 12-10-2018 IPR000506 Ketol-acid reductoisomerase, C-terminal GO:0004455|GO:0009082|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 VAPA_1c25100 0aab3ed77c9ea824665fef350d832004 338 Hamap MF_00435 Ketol-acid reductoisomerase (NADP(+)) [ilvC]. 1 328 45.482 T 12-10-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 VAPA_1c25100 0aab3ed77c9ea824665fef350d832004 338 Pfam PF07991 Acetohydroxy acid isomeroreductase, NADPH-binding domain 14 177 2.9E-74 T 12-10-2018 IPR013116 Ketol-acid reductoisomerase, N-terminal KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 VAPA_1c25100 0aab3ed77c9ea824665fef350d832004 338 Gene3D G3DSA:1.10.3730.40 182 338 4.4E-75 T 12-10-2018 VAPA_1c25100 0aab3ed77c9ea824665fef350d832004 338 TIGRFAM TIGR00465 ilvC: ketol-acid reductoisomerase 14 327 1.7E-135 T 12-10-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 VAPA_1c17010 fb5d6d2a1479c5e24fdc7ecb795c2b90 125 Pfam PF02537 CrcB-like protein, Camphor Resistance (CrcB) 7 116 6.5E-21 T 12-10-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 VAPA_1c17010 fb5d6d2a1479c5e24fdc7ecb795c2b90 125 TIGRFAM TIGR00494 crcB: protein CrcB 6 117 2.1E-24 T 12-10-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 VAPA_1c17010 fb5d6d2a1479c5e24fdc7ecb795c2b90 125 Hamap MF_00454 Putative fluoride ion transporter CrcB [crcB]. 5 121 17.321 T 12-10-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 VAPA_1c46580 544b24cde538fcf811867acadee947a2 257 SUPERFAMILY SSF56529 50 256 2.49E-63 T 12-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 VAPA_1c46580 544b24cde538fcf811867acadee947a2 257 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 61 255 8.5E-50 T 12-10-2018 IPR011234 Fumarylacetoacetase-like, C-terminal GO:0003824 VAPA_1c46580 544b24cde538fcf811867acadee947a2 257 Gene3D G3DSA:3.90.850.10 48 256 5.1E-64 T 12-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 VAPA_1c46580 544b24cde538fcf811867acadee947a2 257 Pfam PF10370 Domain of unknown function (DUF2437) 6 54 2.2E-15 T 12-10-2018 IPR018833 Domain of unknown function DUF2437 VAPA_1c45040 812b37c1cdfd6ddcf6ad9bf09294651a 336 Pfam PF01628 HrcA protein C terminal domain 98 318 8.2E-60 T 12-10-2018 IPR021153 Heat-inducible transcription repressor HrcA, C-terminal GO:0003677|GO:0006355 VAPA_1c45040 812b37c1cdfd6ddcf6ad9bf09294651a 336 SUPERFAMILY SSF46785 1 82 2.63E-22 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c45040 812b37c1cdfd6ddcf6ad9bf09294651a 336 PIRSF PIRSF005485 1 336 2.9E-104 T 12-10-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 VAPA_1c45040 812b37c1cdfd6ddcf6ad9bf09294651a 336 Gene3D G3DSA:3.30.390.60 122 222 1.3E-39 T 12-10-2018 IPR023120 Winged helix-turn-helix transcription repressor, HrcA, inserted dimerising domain superfamily VAPA_1c45040 812b37c1cdfd6ddcf6ad9bf09294651a 336 Hamap MF_00081 Heat-inducible transcription repressor HrcA [hrcA]. 1 325 27.52 T 12-10-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 VAPA_1c45040 812b37c1cdfd6ddcf6ad9bf09294651a 336 Gene3D G3DSA:3.30.450.40 99 330 1.3E-39 T 12-10-2018 IPR029016 GAF-like domain superfamily VAPA_1c45040 812b37c1cdfd6ddcf6ad9bf09294651a 336 TIGRFAM TIGR00331 hrcA: heat-inducible transcription repressor HrcA 3 331 1.9E-93 T 12-10-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 VAPA_1c45040 812b37c1cdfd6ddcf6ad9bf09294651a 336 Gene3D G3DSA:1.10.10.10 1 85 1.8E-30 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c45040 812b37c1cdfd6ddcf6ad9bf09294651a 336 Pfam PF03444 Winged helix-turn-helix transcription repressor, HrcA DNA-binding 4 73 5.7E-7 T 12-10-2018 IPR005104 Winged helix-turn-helix transcription repressor, HrcA DNA-binding domain GO:0003677|GO:0006355 VAPA_1c45040 812b37c1cdfd6ddcf6ad9bf09294651a 336 SUPERFAMILY SSF55781 71 334 2.75E-61 T 12-10-2018 VAPA_1c12620 fa470cdc7a7278cbd3bf4723b51e1918 203 Gene3D G3DSA:1.20.1050.10 80 187 9.4E-75 T 12-10-2018 VAPA_1c12620 fa470cdc7a7278cbd3bf4723b51e1918 203 SUPERFAMILY SSF47616 73 202 3.13E-24 T 12-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily VAPA_1c12620 fa470cdc7a7278cbd3bf4723b51e1918 203 Pfam PF13417 Glutathione S-transferase, N-terminal domain 4 77 4.1E-16 T 12-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 VAPA_1c12620 fa470cdc7a7278cbd3bf4723b51e1918 203 Gene3D G3DSA:3.40.30.10 2 195 9.4E-75 T 12-10-2018 VAPA_1c12620 fa470cdc7a7278cbd3bf4723b51e1918 203 SUPERFAMILY SSF52833 1 101 1.48E-26 T 12-10-2018 IPR036249 Thioredoxin-like superfamily VAPA_1c12620 fa470cdc7a7278cbd3bf4723b51e1918 203 Pfam PF00043 Glutathione S-transferase, C-terminal domain 114 188 1.8E-7 T 12-10-2018 IPR004046 Glutathione S-transferase, C-terminal VAPA_1c22590 d537d3bb53511459b939b34553584399 254 Pfam PF01614 Bacterial transcriptional regulator 135 244 7.5E-16 T 12-10-2018 IPR014757 Transcription regulator IclR, C-terminal VAPA_1c22590 d537d3bb53511459b939b34553584399 254 SUPERFAMILY SSF55781 68 249 9.81E-38 T 12-10-2018 VAPA_1c22590 d537d3bb53511459b939b34553584399 254 SMART SM00346 10 100 6.1E-21 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 VAPA_1c22590 d537d3bb53511459b939b34553584399 254 Pfam PF09339 IclR helix-turn-helix domain 12 60 2.4E-12 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 VAPA_1c22590 d537d3bb53511459b939b34553584399 254 Gene3D G3DSA:3.30.450.40 84 250 3.3E-39 T 12-10-2018 IPR029016 GAF-like domain superfamily VAPA_1c22590 d537d3bb53511459b939b34553584399 254 SUPERFAMILY SSF46785 10 81 2.0E-14 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c22590 d537d3bb53511459b939b34553584399 254 Gene3D G3DSA:1.10.10.10 3 81 2.7E-17 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c04410 7089f890453105a06506a1e9e6219bcc 251 Pfam PF00005 ABC transporter 20 175 1.2E-27 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c04410 7089f890453105a06506a1e9e6219bcc 251 SMART SM00382 28 222 7.4E-9 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c04410 7089f890453105a06506a1e9e6219bcc 251 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 222 244 8.9E-7 T 12-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal VAPA_1c04410 7089f890453105a06506a1e9e6219bcc 251 Gene3D G3DSA:3.40.50.300 1 247 5.9E-57 T 12-10-2018 VAPA_1c04410 7089f890453105a06506a1e9e6219bcc 251 SUPERFAMILY SSF52540 4 245 1.22E-58 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c46670 f872e23669d05b92d4d3bbbc0505a904 278 Pfam PF13189 Cytidylate kinase-like family 3 168 2.8E-26 T 12-10-2018 VAPA_1c46670 f872e23669d05b92d4d3bbbc0505a904 278 Gene3D G3DSA:3.40.50.300 1 188 9.0E-33 T 12-10-2018 VAPA_1c46670 f872e23669d05b92d4d3bbbc0505a904 278 Pfam PF04972 BON domain 203 265 3.6E-12 T 12-10-2018 IPR007055 BON domain VAPA_1c46670 f872e23669d05b92d4d3bbbc0505a904 278 SMART SM00749 204 267 2.4E-4 T 12-10-2018 IPR014004 Transport-associated and nodulation domain, bacteria VAPA_1c43420 0df7dfbba27fea4f8fcc2aa4a5b4973f 169 SUPERFAMILY SSF50341 23 162 1.22E-38 T 12-10-2018 IPR036061 CheW-like domain superfamily GO:0006935|GO:0007165 VAPA_1c43420 0df7dfbba27fea4f8fcc2aa4a5b4973f 169 Gene3D G3DSA:2.40.50.180 43 152 5.1E-40 T 12-10-2018 VAPA_1c43420 0df7dfbba27fea4f8fcc2aa4a5b4973f 169 SMART SM00260 20 157 1.7E-40 T 12-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 VAPA_1c43420 0df7dfbba27fea4f8fcc2aa4a5b4973f 169 Pfam PF01584 CheW-like domain 24 160 2.5E-37 T 12-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 VAPA_1c43420 0df7dfbba27fea4f8fcc2aa4a5b4973f 169 Gene3D G3DSA:2.30.30.40 27 151 5.1E-40 T 12-10-2018 VAPA_1c11270 3ab45e75d2f788f616c5a96992d17f56 772 PRINTS PR00811 Bacterial general secretion pathway protein D signature 417 427 4.1E-27 T 12-10-2018 IPR001775 GspD/PilQ family VAPA_1c11270 3ab45e75d2f788f616c5a96992d17f56 772 PRINTS PR00811 Bacterial general secretion pathway protein D signature 497 521 4.1E-27 T 12-10-2018 IPR001775 GspD/PilQ family VAPA_1c11270 3ab45e75d2f788f616c5a96992d17f56 772 PRINTS PR00811 Bacterial general secretion pathway protein D signature 532 542 4.1E-27 T 12-10-2018 IPR001775 GspD/PilQ family VAPA_1c11270 3ab45e75d2f788f616c5a96992d17f56 772 PRINTS PR00811 Bacterial general secretion pathway protein D signature 632 650 4.1E-27 T 12-10-2018 IPR001775 GspD/PilQ family VAPA_1c11270 3ab45e75d2f788f616c5a96992d17f56 772 PRINTS PR00811 Bacterial general secretion pathway protein D signature 655 669 4.1E-27 T 12-10-2018 IPR001775 GspD/PilQ family VAPA_1c11270 3ab45e75d2f788f616c5a96992d17f56 772 Gene3D G3DSA:3.30.1370.120 208 290 4.5E-13 T 12-10-2018 IPR038591 NolW-like superfamily VAPA_1c11270 3ab45e75d2f788f616c5a96992d17f56 772 Pfam PF00263 Bacterial type II and III secretion system protein 503 667 3.8E-48 T 12-10-2018 IPR004846 Type II/III secretion system GO:0009306 VAPA_1c11270 3ab45e75d2f788f616c5a96992d17f56 772 Pfam PF03958 Bacterial type II/III secretion system short domain 149 209 7.3E-11 T 12-10-2018 IPR005644 NolW-like VAPA_1c11270 3ab45e75d2f788f616c5a96992d17f56 772 Pfam PF03958 Bacterial type II/III secretion system short domain 213 292 3.8E-14 T 12-10-2018 IPR005644 NolW-like VAPA_1c11270 3ab45e75d2f788f616c5a96992d17f56 772 Pfam PF03958 Bacterial type II/III secretion system short domain 304 417 1.3E-14 T 12-10-2018 IPR005644 NolW-like VAPA_1c11270 3ab45e75d2f788f616c5a96992d17f56 772 PRINTS PR01032 Gene IV protein signature 522 545 1.5E-10 T 12-10-2018 VAPA_1c11270 3ab45e75d2f788f616c5a96992d17f56 772 PRINTS PR01032 Gene IV protein signature 595 623 1.5E-10 T 12-10-2018 VAPA_1c11270 3ab45e75d2f788f616c5a96992d17f56 772 TIGRFAM TIGR02517 type_II_gspD: type II secretion system protein D 50 673 2.6E-176 T 12-10-2018 IPR013356 Type II secretion system GspD GO:0008565|GO:0015627|GO:0015628|GO:0019867 VAPA_1c11270 3ab45e75d2f788f616c5a96992d17f56 772 Gene3D G3DSA:3.30.1370.120 43 206 2.4E-51 T 12-10-2018 IPR038591 NolW-like superfamily VAPA_1c25700 bf464a46c036f2f01873df124ad39d86 615 Pfam PF01266 FAD dependent oxidoreductase 251 591 9.6E-39 T 12-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 VAPA_1c25700 bf464a46c036f2f01873df124ad39d86 615 SUPERFAMILY SSF54373 452 550 1.57E-5 T 12-10-2018 VAPA_1c25700 bf464a46c036f2f01873df124ad39d86 615 Gene3D G3DSA:3.40.50.150 5 235 7.6E-83 T 12-10-2018 VAPA_1c25700 bf464a46c036f2f01873df124ad39d86 615 Pfam PF05430 S-adenosyl-L-methionine-dependent methyltransferase 107 227 6.1E-32 T 12-10-2018 IPR008471 MnmC-like methyltransferase GO:0016645|GO:0055114 MetaCyc: PWY-7892 VAPA_1c25700 bf464a46c036f2f01873df124ad39d86 615 Gene3D G3DSA:3.30.9.10 332 551 6.3E-91 T 12-10-2018 VAPA_1c25700 bf464a46c036f2f01873df124ad39d86 615 Gene3D G3DSA:3.50.50.60 250 613 6.3E-91 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c25700 bf464a46c036f2f01873df124ad39d86 615 Hamap MF_01102 tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC [mnmC]. 2 614 21.264 T 12-10-2018 IPR023032 tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC GO:0004808|GO:0008033|GO:0008168|GO:0016645|GO:0055114 MetaCyc: PWY-7892 VAPA_1c25700 bf464a46c036f2f01873df124ad39d86 615 TIGRFAM TIGR03197 MnmC_Cterm: tRNA U-34 5-methylaminomethyl-2-thiouridine biosynthesis protein MnmC, C-terminal domain 250 613 2.2E-74 T 12-10-2018 IPR017610 tRNA U-34 5-methylaminomethyl-2-thiouridine biosynthesis protein MnmC, C-terminal GO:0008168|GO:0016645|GO:0055114 MetaCyc: PWY-7892 VAPA_1c25700 bf464a46c036f2f01873df124ad39d86 615 SUPERFAMILY SSF51971 248 592 3.18E-27 T 12-10-2018 VAPA_1c48190 fcfb192180cccd469be8c2249b772025 152 Gene3D G3DSA:3.40.390.30 7 152 2.4E-38 T 12-10-2018 IPR023091 Metalloprotease catalytic domain superfamily, predicted GO:0004222 VAPA_1c48190 fcfb192180cccd469be8c2249b772025 152 Pfam PF02130 Uncharacterized protein family UPF0054 29 143 1.7E-27 T 12-10-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 VAPA_1c48190 fcfb192180cccd469be8c2249b772025 152 Hamap MF_00009 Endoribonuclease YbeY [ybeY]. 7 148 20.228 T 12-10-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 VAPA_1c48190 fcfb192180cccd469be8c2249b772025 152 TIGRFAM TIGR00043 TIGR00043: rRNA maturation RNase YbeY 43 144 5.8E-29 T 12-10-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 VAPA_1c48190 fcfb192180cccd469be8c2249b772025 152 ProSitePatterns PS01306 Uncharacterized protein family UPF0054 signature. 113 123 - T 12-10-2018 IPR020549 Endoribonuclease YbeY, conserved site VAPA_1c48190 fcfb192180cccd469be8c2249b772025 152 SUPERFAMILY SSF55486 29 150 5.62E-39 T 12-10-2018 VAPA_1c00660 142d2a9070c82219fe44fb2eb14f122a 258 Hamap MF_00267 Probable septum site-determining protein MinC [minC]. 12 258 25.133 T 12-10-2018 IPR013033 Septum formation inhibitor MinC GO:0051726|GO:1901891 VAPA_1c00660 142d2a9070c82219fe44fb2eb14f122a 258 Gene3D G3DSA:2.160.20.70 148 258 1.4E-29 T 12-10-2018 IPR016098 Cyclase-associated protein CAP/septum formation inhibitor MinC, C-terminal GO:0000902 VAPA_1c00660 142d2a9070c82219fe44fb2eb14f122a 258 TIGRFAM TIGR01222 minC: septum site-determining protein MinC 12 257 3.4E-54 T 12-10-2018 IPR013033 Septum formation inhibitor MinC GO:0051726|GO:1901891 VAPA_1c00660 142d2a9070c82219fe44fb2eb14f122a 258 SUPERFAMILY SSF63848 151 257 1.31E-27 T 12-10-2018 IPR036145 Septum formation inhibitor MinC, C-terminal domain superfamily GO:0000902 VAPA_1c00660 142d2a9070c82219fe44fb2eb14f122a 258 Pfam PF03775 Septum formation inhibitor MinC, C-terminal domain 154 254 2.8E-29 T 12-10-2018 IPR005526 Septum formation inhibitor MinC, C-terminal GO:0000902 VAPA_1c00660 142d2a9070c82219fe44fb2eb14f122a 258 Gene3D G3DSA:3.30.750.120 7 128 2.8E-21 T 12-10-2018 IPR038061 MinC, Proteobacteria, N-terminal domain superfamily VAPA_1c00660 142d2a9070c82219fe44fb2eb14f122a 258 Pfam PF05209 Septum formation inhibitor MinC, N-terminal domain 11 111 7.2E-13 T 12-10-2018 IPR007874 Septum formation inhibitor MinC, N-terminal GO:0051302 VAPA_1c51890 fe61c50f8b33e247735410950a4374ff 325 Gene3D G3DSA:3.40.190.150 29 315 2.5E-112 T 12-10-2018 VAPA_1c51890 fe61c50f8b33e247735410950a4374ff 325 Gene3D G3DSA:3.40.190.10 127 250 2.5E-112 T 12-10-2018 VAPA_1c51890 fe61c50f8b33e247735410950a4374ff 325 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 49 320 1.8E-85 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c51890 fe61c50f8b33e247735410950a4374ff 325 SUPERFAMILY SSF53850 115 285 2.76E-17 T 12-10-2018 VAPA_1c51890 fe61c50f8b33e247735410950a4374ff 325 PIRSF PIRSF017082 1 325 5.4E-82 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c21570 5c28b3bca7978685e1f3e956a08146e7 452 SUPERFAMILY SSF55347 155 320 3.01E-51 T 12-10-2018 VAPA_1c21570 5c28b3bca7978685e1f3e956a08146e7 452 Pfam PF00742 Homoserine dehydrogenase 155 333 3.2E-64 T 12-10-2018 IPR001342 Homoserine dehydrogenase, catalytic GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 VAPA_1c21570 5c28b3bca7978685e1f3e956a08146e7 452 PIRSF PIRSF000098 19 450 2.0E-139 T 12-10-2018 IPR016204 Homoserine dehydrogenase GO:0004412|GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 VAPA_1c21570 5c28b3bca7978685e1f3e956a08146e7 452 Gene3D G3DSA:3.30.70.260 367 439 5.6E-142 T 12-10-2018 VAPA_1c21570 5c28b3bca7978685e1f3e956a08146e7 452 Gene3D G3DSA:3.40.50.720 22 358 5.6E-142 T 12-10-2018 VAPA_1c21570 5c28b3bca7978685e1f3e956a08146e7 452 Gene3D G3DSA:3.30.360.10 154 366 5.6E-142 T 12-10-2018 VAPA_1c21570 5c28b3bca7978685e1f3e956a08146e7 452 SUPERFAMILY SSF51735 21 176 8.49E-31 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c21570 5c28b3bca7978685e1f3e956a08146e7 452 ProSitePatterns PS01042 Homoserine dehydrogenase signature. 201 223 - T 12-10-2018 IPR019811 Homoserine dehydrogenase, conserved site GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 VAPA_1c21570 5c28b3bca7978685e1f3e956a08146e7 452 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 28 147 1.5E-21 T 12-10-2018 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 VAPA_2c08100 93c2816b0160536ea041b91017e5043e 259 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 253 1.0E-37 T 12-10-2018 VAPA_2c08100 93c2816b0160536ea041b91017e5043e 259 Gene3D G3DSA:3.40.50.720 1 259 1.6E-61 T 12-10-2018 VAPA_2c08100 93c2816b0160536ea041b91017e5043e 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 1.2E-23 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c08100 93c2816b0160536ea041b91017e5043e 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 1.2E-23 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c08100 93c2816b0160536ea041b91017e5043e 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 218 238 1.2E-23 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c08100 93c2816b0160536ea041b91017e5043e 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 1.2E-23 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c08100 93c2816b0160536ea041b91017e5043e 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 1.2E-23 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c08100 93c2816b0160536ea041b91017e5043e 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 1.2E-23 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c08100 93c2816b0160536ea041b91017e5043e 259 SUPERFAMILY SSF51735 8 254 2.11E-59 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_2c04140 21c33b3c1ed55a0d95fa7698f1ab985a 102 Pfam PF00364 Biotin-requiring enzyme 7 79 1.3E-15 T 12-10-2018 IPR000089 Biotin/lipoyl attachment VAPA_2c04140 21c33b3c1ed55a0d95fa7698f1ab985a 102 SUPERFAMILY SSF51230 4 93 1.31E-22 T 12-10-2018 IPR011053 Single hybrid motif VAPA_2c04140 21c33b3c1ed55a0d95fa7698f1ab985a 102 Gene3D G3DSA:2.40.50.100 2 99 5.1E-25 T 12-10-2018 VAPA_2c10120 c26c0b1748baebe6336ebf9578b70b04 224 Gene3D G3DSA:3.40.50.1000 17 193 4.1E-37 T 12-10-2018 IPR023214 HAD superfamily VAPA_2c10120 c26c0b1748baebe6336ebf9578b70b04 224 SUPERFAMILY SSF56784 15 217 2.03E-37 T 12-10-2018 IPR036412 HAD-like superfamily VAPA_2c10120 c26c0b1748baebe6336ebf9578b70b04 224 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 15 26 4.1E-10 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 VAPA_2c10120 c26c0b1748baebe6336ebf9578b70b04 224 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 132 148 4.1E-10 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 VAPA_2c10120 c26c0b1748baebe6336ebf9578b70b04 224 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 150 170 4.1E-10 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 VAPA_2c10120 c26c0b1748baebe6336ebf9578b70b04 224 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 177 190 4.1E-10 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 VAPA_2c10120 c26c0b1748baebe6336ebf9578b70b04 224 TIGRFAM TIGR01493 HAD-SF-IA-v2: HAD hydrolase, family IA, variant 2 18 177 1.6E-16 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 VAPA_2c10120 c26c0b1748baebe6336ebf9578b70b04 224 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 88 162 5.2E-7 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 VAPA_2c10120 c26c0b1748baebe6336ebf9578b70b04 224 Gene3D G3DSA:1.10.150.240 29 89 4.1E-37 T 12-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 VAPA_2c10120 c26c0b1748baebe6336ebf9578b70b04 224 Pfam PF13419 Haloacid dehalogenase-like hydrolase 39 187 6.7E-14 T 12-10-2018 VAPA_1c40060 df9019385ac8317c2e549faee38421bf 433 Pfam PF07690 Major Facilitator Superfamily 29 383 2.0E-34 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 VAPA_1c40060 df9019385ac8317c2e549faee38421bf 433 Gene3D G3DSA:1.20.1250.20 10 209 1.5E-27 T 12-10-2018 VAPA_1c40060 df9019385ac8317c2e549faee38421bf 433 Gene3D G3DSA:1.20.1250.20 224 423 2.3E-18 T 12-10-2018 VAPA_1c40060 df9019385ac8317c2e549faee38421bf 433 SUPERFAMILY SSF103473 8 414 4.71E-53 T 12-10-2018 IPR036259 MFS transporter superfamily VAPA_2c06180 012eb5d0aa611b06e37043e134570860 530 Gene3D G3DSA:3.10.105.10 273 505 2.5E-119 T 12-10-2018 VAPA_2c06180 012eb5d0aa611b06e37043e134570860 530 Gene3D G3DSA:3.40.190.10 34 272 2.5E-119 T 12-10-2018 VAPA_2c06180 012eb5d0aa611b06e37043e134570860 530 Gene3D G3DSA:3.90.76.10 60 171 2.5E-119 T 12-10-2018 VAPA_2c06180 012eb5d0aa611b06e37043e134570860 530 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 70 436 4.4E-77 T 12-10-2018 IPR000914 Solute-binding protein family 5 domain VAPA_2c06180 012eb5d0aa611b06e37043e134570860 530 SUPERFAMILY SSF53850 25 510 2.53E-118 T 12-10-2018 VAPA_2c06180 012eb5d0aa611b06e37043e134570860 530 PIRSF PIRSF002741 23 521 7.8E-85 T 12-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 VAPA_2c06180 012eb5d0aa611b06e37043e134570860 530 ProSitePatterns PS01040 Bacterial extracellular solute-binding proteins, family 5 signature. 75 96 - T 12-10-2018 IPR023765 Solute-binding protein family 5, conserved site VAPA_1c36240 e0514552e11f621f1d8175af5ec1be23 88 SMART SM01387 7 87 1.8E-52 T 12-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 VAPA_1c36240 e0514552e11f621f1d8175af5ec1be23 88 TIGRFAM TIGR00952 S15_bact: ribosomal protein uS15 6 88 5.0E-37 T 12-10-2018 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 VAPA_1c36240 e0514552e11f621f1d8175af5ec1be23 88 SUPERFAMILY SSF47060 2 88 3.24E-34 T 12-10-2018 IPR009068 S15/NS1, RNA-binding VAPA_1c36240 e0514552e11f621f1d8175af5ec1be23 88 Gene3D G3DSA:1.10.287.10 2 88 8.4E-35 T 12-10-2018 VAPA_1c36240 e0514552e11f621f1d8175af5ec1be23 88 Pfam PF00312 Ribosomal protein S15 7 87 3.0E-37 T 12-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 VAPA_1c36240 e0514552e11f621f1d8175af5ec1be23 88 Hamap MF_01343_B 30S ribosomal protein S15 [rpsO]. 2 88 21.716 T 12-10-2018 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 VAPA_1c36240 e0514552e11f621f1d8175af5ec1be23 88 ProSitePatterns PS00362 Ribosomal protein S15 signature. 38 68 - T 12-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 VAPA_1c36240 e0514552e11f621f1d8175af5ec1be23 88 ProDom PD157043 RIBOSOMAL S15 RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 30S CHLOROPLAST S15 MITOCHONDRIAL TYPE 9 87 3.0E-28 T 12-10-2018 VAPA_1c34350 7412082a88a010920485886efd757211 470 PRINTS PR00344 Bacterial sensor protein C-terminal signature 427 445 5.4E-7 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c34350 7412082a88a010920485886efd757211 470 PRINTS PR00344 Bacterial sensor protein C-terminal signature 395 409 5.4E-7 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c34350 7412082a88a010920485886efd757211 470 SUPERFAMILY SSF55874 305 466 2.36E-32 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_1c34350 7412082a88a010920485886efd757211 470 SMART SM00388 249 314 6.3E-6 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 VAPA_1c34350 7412082a88a010920485886efd757211 470 Gene3D G3DSA:1.10.287.130 200 310 7.1E-17 T 12-10-2018 VAPA_1c34350 7412082a88a010920485886efd757211 470 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 359 464 5.1E-15 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase VAPA_1c34350 7412082a88a010920485886efd757211 470 SUPERFAMILY SSF47384 232 312 3.34E-10 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 VAPA_1c34350 7412082a88a010920485886efd757211 470 Pfam PF08521 Two-component sensor kinase N-terminal 26 169 3.2E-35 T 12-10-2018 IPR013727 Two-component sensor kinase, N-terminal VAPA_1c34350 7412082a88a010920485886efd757211 470 SMART SM00387 358 468 3.6E-27 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase VAPA_1c34350 7412082a88a010920485886efd757211 470 Gene3D G3DSA:3.30.565.10 311 466 2.7E-30 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_2c08920 fbd7f9926dfa8a7b97254d630c3d65af 372 Pfam PF00465 Iron-containing alcohol dehydrogenase 55 345 5.7E-44 T 12-10-2018 IPR001670 Alcohol dehydrogenase, iron-type/glycerol dehydrogenase GldA GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 VAPA_2c08920 fbd7f9926dfa8a7b97254d630c3d65af 372 SUPERFAMILY SSF56796 12 348 3.4E-52 T 12-10-2018 VAPA_2c08920 fbd7f9926dfa8a7b97254d630c3d65af 372 Gene3D G3DSA:3.40.50.1970 5 169 8.3E-26 T 12-10-2018 VAPA_2c08920 fbd7f9926dfa8a7b97254d630c3d65af 372 Gene3D G3DSA:1.20.1090.10 171 371 1.2E-20 T 12-10-2018 VAPA_2c05210 32325d021129495051587ba6dc8077fb 241 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 35 49 5.8E-9 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_2c05210 32325d021129495051587ba6dc8077fb 241 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 49 65 5.8E-9 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_2c05210 32325d021129495051587ba6dc8077fb 241 SMART SM00866 96 234 1.9E-13 T 12-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 VAPA_2c05210 32325d021129495051587ba6dc8077fb 241 Pfam PF07702 UTRA domain 124 233 4.5E-15 T 12-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 VAPA_2c05210 32325d021129495051587ba6dc8077fb 241 Gene3D G3DSA:3.40.1410.10 73 229 2.9E-20 T 12-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily VAPA_2c05210 32325d021129495051587ba6dc8077fb 241 SUPERFAMILY SSF64288 63 240 8.64E-27 T 12-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily VAPA_2c05210 32325d021129495051587ba6dc8077fb 241 Gene3D G3DSA:1.10.10.10 3 72 2.2E-24 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_2c05210 32325d021129495051587ba6dc8077fb 241 SUPERFAMILY SSF46785 7 79 7.58E-23 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_2c05210 32325d021129495051587ba6dc8077fb 241 Pfam PF00392 Bacterial regulatory proteins, gntR family 13 75 4.2E-19 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_2c05210 32325d021129495051587ba6dc8077fb 241 SMART SM00345 16 75 1.5E-19 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_1c47690 a81e6a7833ab583dd625dc7f3931cff8 428 Gene3D G3DSA:3.90.1150.10 11 420 9.2E-169 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 VAPA_1c47690 a81e6a7833ab583dd625dc7f3931cff8 428 Gene3D G3DSA:3.40.640.10 72 320 9.2E-169 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 VAPA_1c47690 a81e6a7833ab583dd625dc7f3931cff8 428 TIGRFAM TIGR00713 hemL: glutamate-1-semialdehyde-2,1-aminomutase 9 427 2.6E-177 T 12-10-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 VAPA_1c47690 a81e6a7833ab583dd625dc7f3931cff8 428 SUPERFAMILY SSF53383 5 426 2.92E-124 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase VAPA_1c47690 a81e6a7833ab583dd625dc7f3931cff8 428 Hamap MF_00375 Glutamate-1-semialdehyde 2,1-aminomutase [hemL]. 6 428 98.065 T 12-10-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 VAPA_1c47690 a81e6a7833ab583dd625dc7f3931cff8 428 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 237 273 - T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 VAPA_1c47690 a81e6a7833ab583dd625dc7f3931cff8 428 Pfam PF00202 Aminotransferase class-III 36 397 1.0E-74 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 VAPA_1c38190 26805c9c9ae884ef8fc2f5fd4a2c8e45 468 TIGRFAM TIGR00797 matE: MATE efflux family protein 27 409 2.8E-47 T 12-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 VAPA_1c38190 26805c9c9ae884ef8fc2f5fd4a2c8e45 468 PIRSF PIRSF006603 3 454 1.7E-74 T 12-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 VAPA_1c38190 26805c9c9ae884ef8fc2f5fd4a2c8e45 468 Pfam PF01554 MatE 258 409 3.3E-19 T 12-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 VAPA_1c38190 26805c9c9ae884ef8fc2f5fd4a2c8e45 468 Pfam PF01554 MatE 27 187 4.3E-21 T 12-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 VAPA_1c44140 de57b37a83707e98b986a05839e16150 226 Gene3D G3DSA:3.40.50.2300 1 127 1.5E-28 T 12-10-2018 VAPA_1c44140 de57b37a83707e98b986a05839e16150 226 Gene3D G3DSA:1.10.10.10 134 225 1.3E-23 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c44140 de57b37a83707e98b986a05839e16150 226 SMART SM00448 2 112 1.7E-29 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_1c44140 de57b37a83707e98b986a05839e16150 226 Pfam PF00072 Response regulator receiver domain 4 113 2.0E-19 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_1c44140 de57b37a83707e98b986a05839e16150 226 SMART SM00862 145 221 3.0E-18 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 VAPA_1c44140 de57b37a83707e98b986a05839e16150 226 SUPERFAMILY SSF52172 2 181 3.7E-33 T 12-10-2018 IPR011006 CheY-like superfamily VAPA_1c44140 de57b37a83707e98b986a05839e16150 226 Pfam PF00486 Transcriptional regulatory protein, C terminal 148 221 8.4E-18 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 VAPA_1c08780 4051a6d9ca20a26bae195b700c5537b3 249 Gene3D G3DSA:3.40.50.720 2 249 5.4E-54 T 12-10-2018 VAPA_1c08780 4051a6d9ca20a26bae195b700c5537b3 249 Pfam PF00106 short chain dehydrogenase 6 201 2.2E-33 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c08780 4051a6d9ca20a26bae195b700c5537b3 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 134 150 2.4E-11 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c08780 4051a6d9ca20a26bae195b700c5537b3 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 160 179 2.4E-11 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c08780 4051a6d9ca20a26bae195b700c5537b3 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 2.4E-11 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c08780 4051a6d9ca20a26bae195b700c5537b3 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 2.4E-11 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c08780 4051a6d9ca20a26bae195b700c5537b3 249 SUPERFAMILY SSF51735 6 238 2.93E-46 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c34630 05b97cd980fcb9f5c2c25184d949bafe 566 Gene3D G3DSA:3.40.50.300 339 559 9.4E-55 T 12-10-2018 VAPA_1c34630 05b97cd980fcb9f5c2c25184d949bafe 566 Pfam PF00005 ABC transporter 363 497 5.0E-22 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c34630 05b97cd980fcb9f5c2c25184d949bafe 566 SUPERFAMILY SSF90123 15 330 1.44E-27 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 VAPA_1c34630 05b97cd980fcb9f5c2c25184d949bafe 566 Gene3D G3DSA:1.20.1560.10 15 324 3.7E-14 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 VAPA_1c34630 05b97cd980fcb9f5c2c25184d949bafe 566 SUPERFAMILY SSF52540 344 547 8.4E-48 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c34630 05b97cd980fcb9f5c2c25184d949bafe 566 ProSitePatterns PS00211 ABC transporters family signature. 470 484 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_1c34630 05b97cd980fcb9f5c2c25184d949bafe 566 SMART SM00382 372 544 2.3E-14 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_2c06930 e4b11934ced1f13c441e049077d858d0 334 Gene3D G3DSA:3.40.50.2300 134 268 1.1E-104 T 12-10-2018 VAPA_2c06930 e4b11934ced1f13c441e049077d858d0 334 Gene3D G3DSA:3.40.50.2300 30 308 1.1E-104 T 12-10-2018 VAPA_2c06930 e4b11934ced1f13c441e049077d858d0 334 SUPERFAMILY SSF53822 27 334 6.12E-64 T 12-10-2018 IPR028082 Periplasmic binding protein-like I VAPA_2c06930 e4b11934ced1f13c441e049077d858d0 334 Pfam PF13407 Periplasmic binding protein domain 33 288 3.8E-50 T 12-10-2018 IPR025997 Periplasmic binding protein VAPA_1c32420 ad5bfe772a9369df6d3afa716a908c13 253 SMART SM00062 20 241 5.7E-30 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF VAPA_1c32420 ad5bfe772a9369df6d3afa716a908c13 253 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 34 234 1.1E-26 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF VAPA_1c32420 ad5bfe772a9369df6d3afa716a908c13 253 Gene3D G3DSA:3.40.190.10 19 230 1.1E-26 T 12-10-2018 VAPA_1c32420 ad5bfe772a9369df6d3afa716a908c13 253 SUPERFAMILY SSF53850 29 237 2.29E-33 T 12-10-2018 VAPA_1c32420 ad5bfe772a9369df6d3afa716a908c13 253 Gene3D G3DSA:3.40.190.10 107 199 1.1E-26 T 12-10-2018 VAPA_1c28140 0def1926857fa9998599c4dc81c93267 543 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 240 268 9.3E-5 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 VAPA_1c28140 0def1926857fa9998599c4dc81c93267 543 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 516 540 7.1E-4 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 VAPA_1c28140 0def1926857fa9998599c4dc81c93267 543 ProSitePatterns PS00211 ABC transporters family signature. 161 175 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_1c28140 0def1926857fa9998599c4dc81c93267 543 SMART SM00382 34 238 2.2E-15 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c28140 0def1926857fa9998599c4dc81c93267 543 SMART SM00382 319 514 3.8E-16 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c28140 0def1926857fa9998599c4dc81c93267 543 SUPERFAMILY SSF52540 9 260 2.98E-60 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c28140 0def1926857fa9998599c4dc81c93267 543 Pfam PF00005 ABC transporter 26 188 2.7E-22 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c28140 0def1926857fa9998599c4dc81c93267 543 Gene3D G3DSA:3.40.50.300 280 542 3.5E-79 T 12-10-2018 VAPA_1c28140 0def1926857fa9998599c4dc81c93267 543 Gene3D G3DSA:3.40.50.300 7 279 5.0E-81 T 12-10-2018 VAPA_1c28140 0def1926857fa9998599c4dc81c93267 543 SUPERFAMILY SSF52540 304 536 3.41E-62 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c28140 0def1926857fa9998599c4dc81c93267 543 ProSitePatterns PS00211 ABC transporters family signature. 437 451 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_1c28140 0def1926857fa9998599c4dc81c93267 543 Pfam PF00005 ABC transporter 311 465 1.2E-27 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c52090 0e9191871cd07597e7e34f3a95717622 697 ProSitePatterns PS00364 Bacterial quinoprotein dehydrogenases signature 2. 266 287 - T 12-10-2018 IPR001479 Quinoprotein dehydrogenase, conserved site GO:0030288|GO:0055114 VAPA_1c52090 0e9191871cd07597e7e34f3a95717622 697 TIGRFAM TIGR03075 PQQ_enz_alc_DH: PQQ-dependent dehydrogenase, methanol/ethanol family 41 564 2.0E-202 T 12-10-2018 IPR017512 PQQ-dependent dehydrogenase, methanol/ethanol family GO:0005509|GO:0016020|GO:0016614|GO:0055114 VAPA_1c52090 0e9191871cd07597e7e34f3a95717622 697 Gene3D G3DSA:1.10.760.10 602 697 3.1E-21 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 VAPA_1c52090 0e9191871cd07597e7e34f3a95717622 697 Gene3D G3DSA:2.140.10.10 20 601 1.2E-250 T 12-10-2018 VAPA_1c52090 0e9191871cd07597e7e34f3a95717622 697 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 613 687 4.4E-10 T 12-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 VAPA_1c52090 0e9191871cd07597e7e34f3a95717622 697 SMART SM00564 504 536 2.3E-5 T 12-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat VAPA_1c52090 0e9191871cd07597e7e34f3a95717622 697 SMART SM00564 144 176 2.8E-7 T 12-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat VAPA_1c52090 0e9191871cd07597e7e34f3a95717622 697 SMART SM00564 294 321 15.0 T 12-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat VAPA_1c52090 0e9191871cd07597e7e34f3a95717622 697 SMART SM00564 190 228 2.8E-4 T 12-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat VAPA_1c52090 0e9191871cd07597e7e34f3a95717622 697 SMART SM00564 94 125 3.2E-7 T 12-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat VAPA_1c52090 0e9191871cd07597e7e34f3a95717622 697 Pfam PF13360 PQQ-like domain 80 225 1.6E-16 T 12-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat VAPA_1c52090 0e9191871cd07597e7e34f3a95717622 697 Pfam PF13360 PQQ-like domain 478 557 1.0E-8 T 12-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat VAPA_1c52090 0e9191871cd07597e7e34f3a95717622 697 SUPERFAMILY SSF46626 605 690 1.55E-19 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 VAPA_1c52090 0e9191871cd07597e7e34f3a95717622 697 SUPERFAMILY SSF50998 44 593 3.66E-171 T 12-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily VAPA_1c17080 f2a9275315d52630b9436ce98a7b3fa2 104 SMART SM00411 1 91 1.3E-40 T 12-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 VAPA_1c17080 f2a9275315d52630b9436ce98a7b3fa2 104 Gene3D G3DSA:4.10.520.10 1 94 4.0E-34 T 12-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 VAPA_1c17080 f2a9275315d52630b9436ce98a7b3fa2 104 PRINTS PR01727 Prokaryotic integration host factor signature 59 72 5.0E-18 T 12-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 VAPA_1c17080 f2a9275315d52630b9436ce98a7b3fa2 104 PRINTS PR01727 Prokaryotic integration host factor signature 75 89 5.0E-18 T 12-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 VAPA_1c17080 f2a9275315d52630b9436ce98a7b3fa2 104 PRINTS PR01727 Prokaryotic integration host factor signature 41 56 5.0E-18 T 12-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 VAPA_1c17080 f2a9275315d52630b9436ce98a7b3fa2 104 SUPERFAMILY SSF47729 1 91 5.45E-31 T 12-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 VAPA_1c17080 f2a9275315d52630b9436ce98a7b3fa2 104 Pfam PF00216 Bacterial DNA-binding protein 1 90 2.2E-31 T 12-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 VAPA_1c17080 f2a9275315d52630b9436ce98a7b3fa2 104 TIGRFAM TIGR00988 hip: integration host factor, beta subunit 1 91 2.2E-36 T 12-10-2018 IPR005685 Integration host factor, beta subunit GO:0003677|GO:0005694|GO:0006310|GO:0006355 VAPA_1c47560 519f7335e24989d2c43642cafd028a90 165 SUPERFAMILY SSF53271 22 136 6.86E-26 T 12-10-2018 IPR029057 Phosphoribosyltransferase-like VAPA_1c47560 519f7335e24989d2c43642cafd028a90 165 Gene3D G3DSA:3.40.50.2020 9 162 2.8E-31 T 12-10-2018 VAPA_1c47560 519f7335e24989d2c43642cafd028a90 165 Pfam PF00156 Phosphoribosyl transferase domain 28 134 2.9E-13 T 12-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 VAPA_2c07140 e0b294a8f4d9e661c961e2a3d884251b 126 Gene3D G3DSA:2.60.120.10 11 125 2.0E-15 T 12-10-2018 IPR014710 RmlC-like jelly roll fold VAPA_2c07140 e0b294a8f4d9e661c961e2a3d884251b 126 SUPERFAMILY SSF51182 15 122 1.24E-15 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily VAPA_1c14920 b7a110868dd0db6d7d3059a737c1a94b 603 Gene3D G3DSA:3.30.70.2570 486 560 7.2E-33 T 12-10-2018 IPR038363 LepA, C-terminal domain superfamily VAPA_1c14920 b7a110868dd0db6d7d3059a737c1a94b 603 Pfam PF00009 Elongation factor Tu GTP binding domain 3 181 9.3E-54 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 VAPA_1c14920 b7a110868dd0db6d7d3059a737c1a94b 603 Pfam PF00679 Elongation factor G C-terminus 406 491 8.4E-23 T 12-10-2018 IPR000640 Elongation factor EFG, domain V-like VAPA_1c14920 b7a110868dd0db6d7d3059a737c1a94b 603 Hamap MF_00071 Elongation factor 4 [lepA]. 1 603 301.449 T 12-10-2018 IPR006297 Elongation factor 4 GO:0005525 VAPA_1c14920 b7a110868dd0db6d7d3059a737c1a94b 603 Pfam PF06421 GTP-binding protein LepA C-terminus 494 600 2.7E-49 T 12-10-2018 IPR013842 GTP-binding protein LepA, C-terminal VAPA_1c14920 b7a110868dd0db6d7d3059a737c1a94b 603 SUPERFAMILY SSF50447 182 278 3.53E-19 T 12-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily VAPA_1c14920 b7a110868dd0db6d7d3059a737c1a94b 603 Gene3D G3DSA:3.40.50.300 1 185 8.7E-71 T 12-10-2018 VAPA_1c14920 b7a110868dd0db6d7d3059a737c1a94b 603 Gene3D G3DSA:3.30.70.870 293 374 5.4E-36 T 12-10-2018 VAPA_1c14920 b7a110868dd0db6d7d3059a737c1a94b 603 SUPERFAMILY SSF54980 299 377 7.55E-18 T 12-10-2018 IPR035647 EF-G domain III/V-like VAPA_1c14920 b7a110868dd0db6d7d3059a737c1a94b 603 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 42 57 - T 12-10-2018 IPR031157 Tr-type G domain, conserved site VAPA_1c14920 b7a110868dd0db6d7d3059a737c1a94b 603 SUPERFAMILY SSF52540 2 205 2.76E-58 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c14920 b7a110868dd0db6d7d3059a737c1a94b 603 TIGRFAM TIGR01393 lepA: elongation factor 4 3 602 1.8E-293 T 12-10-2018 IPR006297 Elongation factor 4 GO:0005525 VAPA_1c14920 b7a110868dd0db6d7d3059a737c1a94b 603 SMART SM00838 405 492 0.0024 T 12-10-2018 IPR000640 Elongation factor EFG, domain V-like VAPA_1c14920 b7a110868dd0db6d7d3059a737c1a94b 603 SUPERFAMILY SSF54980 406 500 4.22E-26 T 12-10-2018 IPR035647 EF-G domain III/V-like VAPA_1c14920 b7a110868dd0db6d7d3059a737c1a94b 603 Gene3D G3DSA:3.30.70.3380 375 485 7.5E-43 T 12-10-2018 VAPA_1c14920 b7a110868dd0db6d7d3059a737c1a94b 603 Gene3D G3DSA:2.40.30.10 186 281 1.2E-33 T 12-10-2018 VAPA_1c14920 b7a110868dd0db6d7d3059a737c1a94b 603 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 6 175 5.0E-20 T 12-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 VAPA_1c14920 b7a110868dd0db6d7d3059a737c1a94b 603 PRINTS PR00315 GTP-binding elongation factor signature 74 84 1.2E-14 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 VAPA_1c14920 b7a110868dd0db6d7d3059a737c1a94b 603 PRINTS PR00315 GTP-binding elongation factor signature 126 135 1.2E-14 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 VAPA_1c14920 b7a110868dd0db6d7d3059a737c1a94b 603 PRINTS PR00315 GTP-binding elongation factor signature 6 19 1.2E-14 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 VAPA_1c14920 b7a110868dd0db6d7d3059a737c1a94b 603 PRINTS PR00315 GTP-binding elongation factor signature 90 101 1.2E-14 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 VAPA_1c14920 b7a110868dd0db6d7d3059a737c1a94b 603 PRINTS PR00315 GTP-binding elongation factor signature 49 57 1.2E-14 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 VAPA_1c14920 b7a110868dd0db6d7d3059a737c1a94b 603 Pfam PF03144 Elongation factor Tu domain 2 205 275 2.2E-7 T 12-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 VAPA_1c43460 9d1cddd40004ef34fce7e1f0ac0b376f 547 SMART SM00304 212 264 4.6E-12 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 VAPA_1c43460 9d1cddd40004ef34fce7e1f0ac0b376f 547 Gene3D G3DSA:1.10.287.950 211 514 5.2E-95 T 12-10-2018 VAPA_1c43460 9d1cddd40004ef34fce7e1f0ac0b376f 547 SUPERFAMILY SSF58104 232 513 5.75E-78 T 12-10-2018 VAPA_1c43460 9d1cddd40004ef34fce7e1f0ac0b376f 547 Pfam PF12729 Four helix bundle sensory module for signal transduction 5 179 3.8E-11 T 12-10-2018 IPR024478 Chemotaxis methyl-accepting receptor HlyB-like, 4HB MCP domain VAPA_1c43460 9d1cddd40004ef34fce7e1f0ac0b376f 547 SMART SM00283 265 512 2.5E-90 T 12-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 VAPA_1c43460 9d1cddd40004ef34fce7e1f0ac0b376f 547 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 440 469 5.5E-62 T 12-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 VAPA_1c43460 9d1cddd40004ef34fce7e1f0ac0b376f 547 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 6 31 5.5E-62 T 12-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 VAPA_1c43460 9d1cddd40004ef34fce7e1f0ac0b376f 547 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 363 390 5.5E-62 T 12-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 VAPA_1c43460 9d1cddd40004ef34fce7e1f0ac0b376f 547 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 286 315 5.5E-62 T 12-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 VAPA_1c43460 9d1cddd40004ef34fce7e1f0ac0b376f 547 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 392 421 5.5E-62 T 12-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 VAPA_1c43460 9d1cddd40004ef34fce7e1f0ac0b376f 547 Pfam PF00672 HAMP domain 212 255 9.8E-10 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 VAPA_1c43460 9d1cddd40004ef34fce7e1f0ac0b376f 547 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 324 480 1.3E-55 T 12-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 VAPA_1c39620 743cc4d0452d3cc0646446ac84aba6d8 482 Gene3D G3DSA:3.30.9.10 160 387 3.7E-69 T 12-10-2018 VAPA_1c39620 743cc4d0452d3cc0646446ac84aba6d8 482 Pfam PF01266 FAD dependent oxidoreductase 67 427 5.1E-52 T 12-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 VAPA_1c39620 743cc4d0452d3cc0646446ac84aba6d8 482 Gene3D G3DSA:3.50.50.60 67 428 3.7E-69 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c39620 743cc4d0452d3cc0646446ac84aba6d8 482 SUPERFAMILY SSF51905 66 445 2.46E-40 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c31080 f40da8e5da98856e1f44275c31ee7d42 296 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 118 269 5.1E-7 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF VAPA_1c31080 f40da8e5da98856e1f44275c31ee7d42 296 SUPERFAMILY SSF53850 40 281 6.25E-19 T 12-10-2018 VAPA_1c31080 f40da8e5da98856e1f44275c31ee7d42 296 Gene3D G3DSA:3.40.190.10 131 246 3.0E-9 T 12-10-2018 VAPA_1c31080 f40da8e5da98856e1f44275c31ee7d42 296 TIGRFAM TIGR03871 ABC_peri_MoxJ_2: quinoprotein dehydrogenase-associated probable ABC transporter substrate-binding protein 43 287 5.1E-85 T 12-10-2018 IPR022448 Quinoprotein dehydrogenase-associated VAPA_1c31080 f40da8e5da98856e1f44275c31ee7d42 296 SMART SM00062 43 285 8.9E-11 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF VAPA_1c31080 f40da8e5da98856e1f44275c31ee7d42 296 Gene3D G3DSA:3.40.190.10 43 269 3.0E-9 T 12-10-2018 VAPA_1c14820 22a9b41814d1afbe23b956b32bf3c83b 325 TIGRFAM TIGR00747 fabH: 3-oxoacyl-[acyl-carrier-protein] synthase III 5 324 1.8E-122 T 12-10-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 VAPA_1c14820 22a9b41814d1afbe23b956b32bf3c83b 325 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 236 324 3.3E-36 T 12-10-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 VAPA_1c14820 22a9b41814d1afbe23b956b32bf3c83b 325 SUPERFAMILY SSF53901 3 324 1.31E-73 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 VAPA_1c14820 22a9b41814d1afbe23b956b32bf3c83b 325 Hamap MF_01815 3-oxoacyl-[acyl-carrier-protein] synthase 3 [fabH]. 3 325 70.681 T 12-10-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 VAPA_1c14820 22a9b41814d1afbe23b956b32bf3c83b 325 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 113 190 2.4E-34 T 12-10-2018 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 VAPA_1c14820 22a9b41814d1afbe23b956b32bf3c83b 325 Gene3D G3DSA:3.40.47.10 2 325 5.9E-131 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 VAPA_1c24960 89d9cbdfd1bc5e5bda79fbc3afff11aa 848 Gene3D G3DSA:3.30.1330.60 720 848 4.6E-14 T 12-10-2018 IPR036737 OmpA-like domain superfamily VAPA_1c24960 89d9cbdfd1bc5e5bda79fbc3afff11aa 848 Pfam PF00691 OmpA family 753 824 1.6E-11 T 12-10-2018 IPR006665 OmpA-like domain VAPA_1c24960 89d9cbdfd1bc5e5bda79fbc3afff11aa 848 Hamap MF_01129 Putative K(+)-stimulated pyrophosphate-energized sodium pump [hppA]. 4 684 25.831 T 12-10-2018 IPR004131 Pyrophosphate-energised proton pump GO:0004427|GO:0009678|GO:0016020|GO:1902600 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 VAPA_1c24960 89d9cbdfd1bc5e5bda79fbc3afff11aa 848 SUPERFAMILY SSF103088 750 846 4.58E-13 T 12-10-2018 IPR036737 OmpA-like domain superfamily VAPA_1c24960 89d9cbdfd1bc5e5bda79fbc3afff11aa 848 PIRSF PIRSF001265 1 692 6.7E-269 T 12-10-2018 IPR004131 Pyrophosphate-energised proton pump GO:0004427|GO:0009678|GO:0016020|GO:1902600 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 VAPA_1c24960 89d9cbdfd1bc5e5bda79fbc3afff11aa 848 Pfam PF03030 Inorganic H+ pyrophosphatase 16 679 1.3E-270 T 12-10-2018 IPR004131 Pyrophosphate-energised proton pump GO:0004427|GO:0009678|GO:0016020|GO:1902600 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 VAPA_1c24960 89d9cbdfd1bc5e5bda79fbc3afff11aa 848 TIGRFAM TIGR01104 V_PPase: V-type H(+)-translocating pyrophosphatase 8 685 5.4E-268 T 12-10-2018 IPR004131 Pyrophosphate-energised proton pump GO:0004427|GO:0009678|GO:0016020|GO:1902600 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 VAPA_1c11180 e504dad62fa4ad1aadc2181753bf5671 186 SUPERFAMILY SSF109604 5 62 5.45E-6 T 12-10-2018 VAPA_1c11180 e504dad62fa4ad1aadc2181753bf5671 186 Gene3D G3DSA:1.10.3210.10 3 186 1.1E-56 T 12-10-2018 VAPA_1c11180 e504dad62fa4ad1aadc2181753bf5671 186 TIGRFAM TIGR03276 Phn-HD: phosphonate degradation operons associated HDIG domain protein 5 184 3.3E-70 T 12-10-2018 IPR017670 Phosphonate degradation operon associated HDIG domain protein VAPA_1c51430 ceaa0d93bc40139ab3a43dcdf0ac24b9 273 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 81 264 6.9E-10 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 VAPA_1c51430 ceaa0d93bc40139ab3a43dcdf0ac24b9 273 SUPERFAMILY SSF161098 2 257 1.7E-43 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c51430 ceaa0d93bc40139ab3a43dcdf0ac24b9 273 Gene3D G3DSA:1.10.3720.10 5 268 3.0E-45 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c43190 35b4300d81193bcd6639b73779a66922 109 Pfam PF05400 Flagellar protein FliT 21 105 1.6E-16 T 12-10-2018 IPR008622 Flagellar protein FliT VAPA_1c43190 35b4300d81193bcd6639b73779a66922 109 Gene3D G3DSA:1.20.58.380 5 92 1.8E-16 T 12-10-2018 VAPA_2c11130 1d443f0c99dc6f7e1ae7144eae8b20db 768 Gene3D G3DSA:2.40.40.20 601 760 9.6E-40 T 12-10-2018 VAPA_2c11130 1d443f0c99dc6f7e1ae7144eae8b20db 768 Gene3D G3DSA:3.40.50.740 54 519 5.6E-181 T 12-10-2018 VAPA_2c11130 1d443f0c99dc6f7e1ae7144eae8b20db 768 Gene3D G3DSA:3.90.55.10 51 560 5.6E-181 T 12-10-2018 VAPA_2c11130 1d443f0c99dc6f7e1ae7144eae8b20db 768 Gene3D G3DSA:3.40.228.10 147 592 5.6E-181 T 12-10-2018 VAPA_2c11130 1d443f0c99dc6f7e1ae7144eae8b20db 768 SUPERFAMILY SSF53706 21 625 1.33E-143 T 12-10-2018 VAPA_2c11130 1d443f0c99dc6f7e1ae7144eae8b20db 768 Pfam PF01568 Molydopterin dinucleotide binding domain 623 738 3.0E-21 T 12-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 VAPA_2c11130 1d443f0c99dc6f7e1ae7144eae8b20db 768 SUPERFAMILY SSF50692 616 763 4.97E-36 T 12-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily VAPA_2c11130 1d443f0c99dc6f7e1ae7144eae8b20db 768 Pfam PF00384 Molybdopterin oxidoreductase 54 510 2.0E-57 T 12-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VAPA_1c30100 60a21f257284a420bf5eceeffec28f12 320 Gene3D G3DSA:1.10.10.60 210 320 3.8E-30 T 12-10-2018 VAPA_1c30100 60a21f257284a420bf5eceeffec28f12 320 SUPERFAMILY SSF51215 72 156 8.76E-5 T 12-10-2018 IPR037923 Transcription regulator HTH-like VAPA_1c30100 60a21f257284a420bf5eceeffec28f12 320 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 299 315 1.8E-6 T 12-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 VAPA_1c30100 60a21f257284a420bf5eceeffec28f12 320 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 284 299 1.8E-6 T 12-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 VAPA_1c30100 60a21f257284a420bf5eceeffec28f12 320 SMART SM00342 230 315 8.7E-25 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 VAPA_1c30100 60a21f257284a420bf5eceeffec28f12 320 Pfam PF12833 Helix-turn-helix domain 236 317 1.3E-22 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 VAPA_1c30100 60a21f257284a420bf5eceeffec28f12 320 Pfam PF14525 AraC-binding-like domain 19 194 1.2E-30 T 12-10-2018 IPR035418 Transcription regulator HTH, AraC- type, ligand binding domain-like VAPA_1c30100 60a21f257284a420bf5eceeffec28f12 320 SUPERFAMILY SSF46689 266 318 2.11E-11 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 VAPA_2c11570 5c8d0839a2f4e880adc240acb794c845 299 Pfam PF06007 Phosphonate metabolism protein PhnJ 6 277 1.2E-147 T 12-10-2018 IPR010306 Alpha-D-ribose 1-methylphosphonate 5-phosphate C-P-lyase GO:0016829|GO:0019700|GO:0051539 KEGG: 00440+4.7.1.1|MetaCyc: PWY-7399|MetaCyc: PWY-7805|MetaCyc: PWY-7807 VAPA_2c11570 5c8d0839a2f4e880adc240acb794c845 299 PIRSF PIRSF011468 1 287 1.2E-160 T 12-10-2018 IPR010306 Alpha-D-ribose 1-methylphosphonate 5-phosphate C-P-lyase GO:0016829|GO:0019700|GO:0051539 KEGG: 00440+4.7.1.1|MetaCyc: PWY-7399|MetaCyc: PWY-7805|MetaCyc: PWY-7807 VAPA_1c51400 e9889361b94bd2625b1a77dd2a184c6e 255 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 92 247 4.4E-9 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 VAPA_1c51400 e9889361b94bd2625b1a77dd2a184c6e 255 Gene3D G3DSA:1.10.3720.10 1 255 1.5E-36 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c51400 e9889361b94bd2625b1a77dd2a184c6e 255 SUPERFAMILY SSF161098 5 251 1.03E-37 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c43590 ce2da2d1a644c650fed841e65e38972d 149 Gene3D G3DSA:1.20.58.300 1 122 3.0E-31 T 12-10-2018 VAPA_1c43590 ce2da2d1a644c650fed841e65e38972d 149 Pfam PF05130 FlgN protein 5 133 3.4E-24 T 12-10-2018 IPR007809 FlgN-like protein GO:0005515|GO:0044780 VAPA_1c43590 ce2da2d1a644c650fed841e65e38972d 149 SUPERFAMILY SSF140566 4 122 3.27E-21 T 12-10-2018 IPR036679 FlgN-like superfamily GO:0005515|GO:0044780 VAPA_1c07460 0af6d8f9a6a8432cc52d02a66a91c42b 195 Pfam PF14334 Domain of unknown function (DUF4390) 25 184 8.0E-48 T 12-10-2018 IPR025500 Protein of unknown function DUF4390 VAPA_2c09910 064c63234b50aee627c62a3ddf23cd77 493 Pfam PF00171 Aldehyde dehydrogenase family 24 481 1.3E-152 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 VAPA_2c09910 064c63234b50aee627c62a3ddf23cd77 493 SUPERFAMILY SSF53720 13 481 3.4E-153 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 VAPA_2c09910 064c63234b50aee627c62a3ddf23cd77 493 Gene3D G3DSA:3.40.309.10 260 451 8.2E-161 T 12-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 VAPA_2c09910 064c63234b50aee627c62a3ddf23cd77 493 Gene3D G3DSA:3.40.605.10 20 479 8.2E-161 T 12-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 VAPA_1c36130 eb7a8fda6801cc7b9430b4c24d696a3a 446 Pfam PF10589 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region 352 433 7.7E-32 T 12-10-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VAPA_1c36130 eb7a8fda6801cc7b9430b4c24d696a3a 446 SUPERFAMILY SSF142019 35 260 3.27E-82 T 12-10-2018 IPR037225 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VAPA_1c36130 eb7a8fda6801cc7b9430b4c24d696a3a 446 Pfam PF10531 SLBB domain 263 311 2.0E-12 T 12-10-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VAPA_1c36130 eb7a8fda6801cc7b9430b4c24d696a3a 446 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 68 239 8.1E-46 T 12-10-2018 IPR011538 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VAPA_1c36130 eb7a8fda6801cc7b9430b4c24d696a3a 446 SUPERFAMILY SSF140490 346 440 2.09E-36 T 12-10-2018 IPR037207 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VAPA_1c36130 eb7a8fda6801cc7b9430b4c24d696a3a 446 TIGRFAM TIGR01959 nuoF_fam: NADH oxidoreductase (quinone), F subunit 35 434 6.1E-192 T 12-10-2018 IPR011537 NADH ubiquinone oxidoreductase, F subunit GO:0010181|GO:0016651|GO:0051287|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VAPA_1c36130 eb7a8fda6801cc7b9430b4c24d696a3a 446 ProSitePatterns PS00645 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 2. 362 373 - T 12-10-2018 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VAPA_1c36130 eb7a8fda6801cc7b9430b4c24d696a3a 446 Gene3D G3DSA:1.20.1440.230 347 444 6.8E-34 T 12-10-2018 IPR037207 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VAPA_1c36130 eb7a8fda6801cc7b9430b4c24d696a3a 446 SMART SM00928 349 394 1.5E-25 T 12-10-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VAPA_1c36130 eb7a8fda6801cc7b9430b4c24d696a3a 446 Gene3D G3DSA:3.10.20.600 252 346 1.4E-35 T 12-10-2018 VAPA_1c36130 eb7a8fda6801cc7b9430b4c24d696a3a 446 SUPERFAMILY SSF142984 261 344 2.75E-26 T 12-10-2018 VAPA_1c36130 eb7a8fda6801cc7b9430b4c24d696a3a 446 Gene3D G3DSA:3.40.50.11540 73 250 2.5E-74 T 12-10-2018 IPR037225 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VAPA_2c01250 00a7cc6258deed31eded486484576f15 123 SUPERFAMILY SSF54593 5 121 6.71E-21 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase VAPA_2c01250 00a7cc6258deed31eded486484576f15 123 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 6 117 2.8E-13 T 12-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain VAPA_2c01250 00a7cc6258deed31eded486484576f15 123 Gene3D G3DSA:3.10.180.10 1 120 1.7E-21 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase VAPA_1c36330 dee37c676234ed0351e0c2632ce5388b 269 TIGRFAM TIGR01184 ntrCD: nitrate ABC transporter, ATP-binding proteins C and D 27 257 1.7E-103 T 12-10-2018 IPR005890 Nitrate transport ATP-binding subunit C/D GO:0015112|GO:0015706|GO:0016020 VAPA_1c36330 dee37c676234ed0351e0c2632ce5388b 269 SUPERFAMILY SSF52540 8 229 8.59E-67 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c36330 dee37c676234ed0351e0c2632ce5388b 269 SMART SM00382 36 219 3.3E-18 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c36330 dee37c676234ed0351e0c2632ce5388b 269 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_1c36330 dee37c676234ed0351e0c2632ce5388b 269 Gene3D G3DSA:3.40.50.300 5 254 5.1E-62 T 12-10-2018 VAPA_1c36330 dee37c676234ed0351e0c2632ce5388b 269 Pfam PF00005 ABC transporter 27 169 2.2E-30 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_2c03420 8507bc6dc2fecd61243d5685cf7366c8 278 SUPERFAMILY SSF52402 2 147 9.21E-10 T 12-10-2018 VAPA_2c03420 8507bc6dc2fecd61243d5685cf7366c8 278 PRINTS PR01438 Universal stress protein signature 156 174 5.0E-8 T 12-10-2018 IPR006015 Universal stress protein A VAPA_2c03420 8507bc6dc2fecd61243d5685cf7366c8 278 PRINTS PR01438 Universal stress protein signature 256 278 5.0E-8 T 12-10-2018 IPR006015 Universal stress protein A VAPA_2c03420 8507bc6dc2fecd61243d5685cf7366c8 278 PRINTS PR01438 Universal stress protein signature 238 250 5.0E-8 T 12-10-2018 IPR006015 Universal stress protein A VAPA_2c03420 8507bc6dc2fecd61243d5685cf7366c8 278 Pfam PF00582 Universal stress protein family 229 277 3.0E-5 T 12-10-2018 IPR006016 UspA VAPA_2c03420 8507bc6dc2fecd61243d5685cf7366c8 278 SUPERFAMILY SSF52402 157 277 4.19E-18 T 12-10-2018 VAPA_2c03420 8507bc6dc2fecd61243d5685cf7366c8 278 Gene3D G3DSA:3.40.50.12370 5 278 7.4E-29 T 12-10-2018 VAPA_1c42640 b169fc0fa178ef02359c3d671e313b88 447 Pfam PF07730 Histidine kinase 250 316 4.1E-10 T 12-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 VAPA_1c42640 b169fc0fa178ef02359c3d671e313b88 447 Gene3D G3DSA:3.30.565.10 314 445 7.4E-31 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_1c42640 b169fc0fa178ef02359c3d671e313b88 447 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 356 442 1.4E-8 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase VAPA_1c42640 b169fc0fa178ef02359c3d671e313b88 447 Pfam PF05227 CHASE3 domain 40 171 2.3E-34 T 12-10-2018 IPR007891 CHASE3 VAPA_1c42640 b169fc0fa178ef02359c3d671e313b88 447 SMART SM00387 352 445 2.7E-6 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase VAPA_1c42640 b169fc0fa178ef02359c3d671e313b88 447 Gene3D G3DSA:1.20.1440.210 45 171 7.1E-29 T 12-10-2018 VAPA_1c42640 b169fc0fa178ef02359c3d671e313b88 447 SUPERFAMILY SSF55874 321 442 1.06E-18 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_2c08290 f4ea5c3a4f607904ef5a0338cdebb7de 287 SUPERFAMILY SSF52499 4 275 4.71E-13 T 12-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 VAPA_2c08290 f4ea5c3a4f607904ef5a0338cdebb7de 287 Gene3D G3DSA:3.40.50.850 6 274 2.0E-42 T 12-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 VAPA_1c27900 ca7fd8d6066a8600200c386353e307d9 244 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 241 1.7E-58 T 12-10-2018 VAPA_1c27900 ca7fd8d6066a8600200c386353e307d9 244 SUPERFAMILY SSF51735 5 241 7.3E-74 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c27900 ca7fd8d6066a8600200c386353e307d9 244 Gene3D G3DSA:3.40.50.720 1 243 6.7E-76 T 12-10-2018 VAPA_1c27900 ca7fd8d6066a8600200c386353e307d9 244 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 137 165 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 VAPA_1c27900 ca7fd8d6066a8600200c386353e307d9 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 205 225 3.6E-36 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c27900 ca7fd8d6066a8600200c386353e307d9 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 150 169 3.6E-36 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c27900 ca7fd8d6066a8600200c386353e307d9 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 3.6E-36 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c27900 ca7fd8d6066a8600200c386353e307d9 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 124 140 3.6E-36 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c27900 ca7fd8d6066a8600200c386353e307d9 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 171 188 3.6E-36 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c27900 ca7fd8d6066a8600200c386353e307d9 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 3.6E-36 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c45780 b9e07649afbb66f1bb02af0c1a979fb6 329 Gene3D G3DSA:3.40.190.10 128 253 1.5E-86 T 12-10-2018 VAPA_1c45780 b9e07649afbb66f1bb02af0c1a979fb6 329 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 49 324 4.2E-65 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c45780 b9e07649afbb66f1bb02af0c1a979fb6 329 PIRSF PIRSF017082 1 328 1.1E-60 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c45780 b9e07649afbb66f1bb02af0c1a979fb6 329 Gene3D G3DSA:3.40.190.150 34 318 1.5E-86 T 12-10-2018 VAPA_1c09530 e021b3284ff3fa4a1a13f07a9e375d2d 232 Pfam PF04340 Protein of unknown function, DUF484 15 229 1.6E-25 T 12-10-2018 IPR007435 Protein of unknown function DUF484 VAPA_1c09530 e021b3284ff3fa4a1a13f07a9e375d2d 232 Gene3D G3DSA:3.30.450.40 50 231 2.2E-46 T 12-10-2018 IPR029016 GAF-like domain superfamily VAPA_1c31330 2681107296f8d6537e8c57a9cff1e780 246 Pfam PF00977 Histidine biosynthesis protein 7 239 4.0E-22 T 12-10-2018 IPR006062 Histidine biosynthesis GO:0000105 VAPA_1c31330 2681107296f8d6537e8c57a9cff1e780 246 SUPERFAMILY SSF51366 7 238 5.77E-28 T 12-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 VAPA_1c31330 2681107296f8d6537e8c57a9cff1e780 246 Gene3D G3DSA:3.20.20.70 2 244 1.5E-38 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 VAPA_2c01430 921ce3fa775dd13cc836436fa5a2a92a 290 SUPERFAMILY SSF51735 3 164 8.6E-35 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_2c01430 921ce3fa775dd13cc836436fa5a2a92a 290 PIRSF PIRSF000103 1 276 1.1E-68 T 12-10-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 VAPA_2c01430 921ce3fa775dd13cc836436fa5a2a92a 290 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 4 164 1.5E-35 T 12-10-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 VAPA_2c01430 921ce3fa775dd13cc836436fa5a2a92a 290 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 167 273 3.8E-15 T 12-10-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 VAPA_2c01430 921ce3fa775dd13cc836436fa5a2a92a 290 Gene3D G3DSA:3.40.50.720 1 164 3.1E-43 T 12-10-2018 VAPA_2c01430 921ce3fa775dd13cc836436fa5a2a92a 290 SUPERFAMILY SSF48179 165 274 4.42E-22 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 VAPA_2c01430 921ce3fa775dd13cc836436fa5a2a92a 290 Gene3D G3DSA:1.10.1040.10 165 279 3.3E-19 T 12-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 VAPA_1c54850 dfa77bc3eda9ae2f2aae10340c824f80 473 SUPERFAMILY SSF54534 326 427 4.91E-29 T 12-10-2018 VAPA_1c54850 dfa77bc3eda9ae2f2aae10340c824f80 473 Pfam PF09312 SurA N-terminal domain 68 181 5.2E-23 T 12-10-2018 IPR015391 SurA N-terminal VAPA_1c54850 dfa77bc3eda9ae2f2aae10340c824f80 473 Gene3D G3DSA:1.10.4030.10 63 187 1.3E-26 T 12-10-2018 VAPA_1c54850 dfa77bc3eda9ae2f2aae10340c824f80 473 SUPERFAMILY SSF54534 216 316 6.08E-22 T 12-10-2018 VAPA_1c54850 dfa77bc3eda9ae2f2aae10340c824f80 473 Hamap MF_01183 Chaperone SurA [surA]. 10 470 29.366 T 12-10-2018 IPR023034 Peptidyl-prolyl isomerase SurA GO:0003755|GO:0006457|GO:0030288|GO:0042277|GO:0043165|GO:0050821|GO:0051082|GO:0060274 VAPA_1c54850 dfa77bc3eda9ae2f2aae10340c824f80 473 ProSitePatterns PS01096 PpiC-type peptidyl-prolyl cis-trans isomerase signature. 364 384 - T 12-10-2018 IPR023058 Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site Reactome: R-HSA-1169408|Reactome: R-HSA-6804756|Reactome: R-HSA-6811555|Reactome: R-HSA-936440 VAPA_1c54850 dfa77bc3eda9ae2f2aae10340c824f80 473 Gene3D G3DSA:3.10.50.40 326 427 1.7E-72 T 12-10-2018 VAPA_1c54850 dfa77bc3eda9ae2f2aae10340c824f80 473 SUPERFAMILY SSF109998 69 243 1.43E-30 T 12-10-2018 IPR027304 Trigger factor/SurA domain superfamily VAPA_1c54850 dfa77bc3eda9ae2f2aae10340c824f80 473 Gene3D G3DSA:3.10.50.40 217 428 1.7E-72 T 12-10-2018 VAPA_1c54850 dfa77bc3eda9ae2f2aae10340c824f80 473 Pfam PF00639 PPIC-type PPIASE domain 332 423 6.7E-23 T 12-10-2018 IPR000297 Peptidyl-prolyl cis-trans isomerase, PpiC-type GO:0003755 VAPA_1c54850 dfa77bc3eda9ae2f2aae10340c824f80 473 Pfam PF00639 PPIC-type PPIASE domain 220 312 9.0E-17 T 12-10-2018 IPR000297 Peptidyl-prolyl cis-trans isomerase, PpiC-type GO:0003755 VAPA_1c15980 5ef14ccadcc3715ffc7a2f7cc5147203 595 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 571 592 2.7E-6 T 12-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal VAPA_1c15980 5ef14ccadcc3715ffc7a2f7cc5147203 595 SMART SM00382 372 570 5.8E-8 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c15980 5ef14ccadcc3715ffc7a2f7cc5147203 595 SUPERFAMILY SSF52540 347 590 2.19E-59 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c15980 5ef14ccadcc3715ffc7a2f7cc5147203 595 Pfam PF00005 ABC transporter 364 521 1.4E-25 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c15980 5ef14ccadcc3715ffc7a2f7cc5147203 595 Gene3D G3DSA:3.40.50.300 344 594 1.8E-57 T 12-10-2018 VAPA_1c15980 5ef14ccadcc3715ffc7a2f7cc5147203 595 Pfam PF02653 Branched-chain amino acid transport system / permease component 31 299 1.1E-26 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 VAPA_1c51030 f9907e2ba7b0973ec7e04892a608f1b0 405 Pfam PF07943 Penicillin-binding protein 5, C-terminal domain 299 389 8.4E-19 T 12-10-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 VAPA_1c51030 f9907e2ba7b0973ec7e04892a608f1b0 405 SUPERFAMILY SSF56601 27 297 2.17E-73 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like VAPA_1c51030 f9907e2ba7b0973ec7e04892a608f1b0 405 SMART SM00936 299 389 3.0E-29 T 12-10-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 VAPA_1c51030 f9907e2ba7b0973ec7e04892a608f1b0 405 Gene3D G3DSA:2.60.410.10 299 389 1.7E-23 T 12-10-2018 IPR037167 D-Ala-D-Ala carboxypeptidase, C-terminal domain superfamily GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 VAPA_1c51030 f9907e2ba7b0973ec7e04892a608f1b0 405 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 43 278 1.6E-73 T 12-10-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 VAPA_1c51030 f9907e2ba7b0973ec7e04892a608f1b0 405 SUPERFAMILY SSF69189 299 391 1.57E-21 T 12-10-2018 IPR015956 Penicillin-binding protein, C-terminal domain superfamily GO:0004180|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 VAPA_1c51030 f9907e2ba7b0973ec7e04892a608f1b0 405 Gene3D G3DSA:3.40.710.10 38 297 2.0E-83 T 12-10-2018 VAPA_1c51030 f9907e2ba7b0973ec7e04892a608f1b0 405 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 130 147 6.7E-19 T 12-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 VAPA_1c51030 f9907e2ba7b0973ec7e04892a608f1b0 405 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 157 170 6.7E-19 T 12-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 VAPA_1c51030 f9907e2ba7b0973ec7e04892a608f1b0 405 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 77 88 6.7E-19 T 12-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 VAPA_1c30560 28ce24241b38ada3088cf41b8cadde67 243 SUPERFAMILY SSF56784 19 238 2.81E-36 T 12-10-2018 IPR036412 HAD-like superfamily VAPA_1c30560 28ce24241b38ada3088cf41b8cadde67 243 Gene3D G3DSA:3.40.50.1000 21 234 3.9E-54 T 12-10-2018 IPR023214 HAD superfamily VAPA_1c30560 28ce24241b38ada3088cf41b8cadde67 243 Pfam PF13419 Haloacid dehalogenase-like hydrolase 108 213 7.6E-10 T 12-10-2018 VAPA_1c30560 28ce24241b38ada3088cf41b8cadde67 243 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 109 208 8.7E-8 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 VAPA_1c30560 28ce24241b38ada3088cf41b8cadde67 243 Gene3D G3DSA:1.20.120.1600 33 117 3.9E-54 T 12-10-2018 VAPA_1c50570 0bdc55a0e774bf2e88f90b4c6f9c3777 156 Gene3D G3DSA:1.20.5.620 62 122 3.9E-8 T 12-10-2018 VAPA_1c50570 0bdc55a0e774bf2e88f90b4c6f9c3777 156 TIGRFAM TIGR01144 ATP_synt_b: ATP synthase F0, B subunit 10 155 3.4E-39 T 12-10-2018 IPR005864 ATP synthase, F0 complex, subunit b, bacterial GO:0015078|GO:0015986|GO:0045263 VAPA_1c50570 0bdc55a0e774bf2e88f90b4c6f9c3777 156 Pfam PF00430 ATP synthase B/B' CF(0) 6 136 2.3E-27 T 12-10-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 VAPA_1c50570 0bdc55a0e774bf2e88f90b4c6f9c3777 156 SUPERFAMILY SSF81573 63 121 3.66E-9 T 12-10-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain superfamily VAPA_1c50570 0bdc55a0e774bf2e88f90b4c6f9c3777 156 Hamap MF_01398 ATP synthase subunit b [atpF]. 1 138 12.569 T 12-10-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 VAPA_1c30820 002b5b8c88b76a87cf4778eec57c1d89 370 SUPERFAMILY SSF46785 5 138 1.29E-22 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c30820 002b5b8c88b76a87cf4778eec57c1d89 370 SUPERFAMILY SSF53850 135 342 1.88E-17 T 12-10-2018 VAPA_1c30820 002b5b8c88b76a87cf4778eec57c1d89 370 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 24 82 4.0E-10 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c30820 002b5b8c88b76a87cf4778eec57c1d89 370 Pfam PF12727 PBP superfamily domain 147 323 1.8E-51 T 12-10-2018 IPR024370 PBP domain VAPA_1c30820 002b5b8c88b76a87cf4778eec57c1d89 370 Gene3D G3DSA:3.40.190.10 192 201 1.2E-7 T 12-10-2018 VAPA_1c30820 002b5b8c88b76a87cf4778eec57c1d89 370 Gene3D G3DSA:3.40.190.10 202 286 1.2E-7 T 12-10-2018 VAPA_1c30820 002b5b8c88b76a87cf4778eec57c1d89 370 Gene3D G3DSA:1.10.10.10 1 113 7.8E-25 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c47890 346ae9b686a8a3e45fa7e375877dc838 618 Gene3D G3DSA:2.60.40.3650 18 195 1.2E-55 T 12-10-2018 VAPA_1c47890 346ae9b686a8a3e45fa7e375877dc838 618 SUPERFAMILY SSF55486 247 475 7.25E-16 T 12-10-2018 VAPA_1c47890 346ae9b686a8a3e45fa7e375877dc838 618 Gene3D G3DSA:1.10.390.60 197 477 3.7E-101 T 12-10-2018 VAPA_1c47890 346ae9b686a8a3e45fa7e375877dc838 618 PIRSF PIRSF016493 14 561 5.5E-182 T 12-10-2018 IPR024191 Peptidase M61 VAPA_1c47890 346ae9b686a8a3e45fa7e375877dc838 618 Pfam PF05299 M61 glycyl aminopeptidase 300 416 2.1E-47 T 12-10-2018 IPR007963 Peptidase M61, catalytic domain VAPA_2c02960 268bdf4c7f7c94aeef8cf87b18ad4bcc 135 SUPERFAMILY SSF55298 8 130 1.12E-36 T 12-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 VAPA_2c02960 268bdf4c7f7c94aeef8cf87b18ad4bcc 135 Pfam PF01042 Endoribonuclease L-PSP 13 127 7.9E-27 T 12-10-2018 IPR006175 YjgF/YER057c/UK114 family Reactome: R-HSA-8849175 VAPA_2c02960 268bdf4c7f7c94aeef8cf87b18ad4bcc 135 Gene3D G3DSA:3.30.1330.40 1 131 1.1E-41 T 12-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 VAPA_1c44190 88fa955c1cce5b54d578f6fcec9bf88e 230 Gene3D G3DSA:1.10.10.10 135 228 5.9E-28 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c44190 88fa955c1cce5b54d578f6fcec9bf88e 230 Gene3D G3DSA:3.40.50.2300 1 134 4.7E-35 T 12-10-2018 VAPA_1c44190 88fa955c1cce5b54d578f6fcec9bf88e 230 SMART SM00862 148 224 3.4E-21 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 VAPA_1c44190 88fa955c1cce5b54d578f6fcec9bf88e 230 SUPERFAMILY SSF52172 1 127 1.02E-39 T 12-10-2018 IPR011006 CheY-like superfamily VAPA_1c44190 88fa955c1cce5b54d578f6fcec9bf88e 230 SMART SM00448 2 112 1.5E-41 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_1c44190 88fa955c1cce5b54d578f6fcec9bf88e 230 SUPERFAMILY SSF46894 133 225 8.0E-24 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 VAPA_1c44190 88fa955c1cce5b54d578f6fcec9bf88e 230 Pfam PF00486 Transcriptional regulatory protein, C terminal 148 223 1.6E-20 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 VAPA_1c44190 88fa955c1cce5b54d578f6fcec9bf88e 230 Pfam PF00072 Response regulator receiver domain 4 113 3.3E-25 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_1c17660 083bc3232c9f68453cfbc89319e093d8 270 SUPERFAMILY SSF53474 4 266 1.04E-55 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c17660 083bc3232c9f68453cfbc89319e093d8 270 Gene3D G3DSA:3.40.50.1820 2 268 1.4E-54 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c17660 083bc3232c9f68453cfbc89319e093d8 270 PRINTS PR00111 Alpha/beta hydrolase fold signature 93 106 3.4E-10 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 VAPA_1c17660 083bc3232c9f68453cfbc89319e093d8 270 PRINTS PR00111 Alpha/beta hydrolase fold signature 50 65 3.4E-10 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 VAPA_1c17660 083bc3232c9f68453cfbc89319e093d8 270 PRINTS PR00111 Alpha/beta hydrolase fold signature 107 120 3.4E-10 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 VAPA_1c17660 083bc3232c9f68453cfbc89319e093d8 270 PRINTS PR00111 Alpha/beta hydrolase fold signature 213 227 3.4E-10 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 VAPA_1c17660 083bc3232c9f68453cfbc89319e093d8 270 PRINTS PR00412 Epoxide hydrolase signature 107 120 3.2E-7 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 VAPA_1c17660 083bc3232c9f68453cfbc89319e093d8 270 PRINTS PR00412 Epoxide hydrolase signature 93 106 3.2E-7 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 VAPA_1c17660 083bc3232c9f68453cfbc89319e093d8 270 PRINTS PR00412 Epoxide hydrolase signature 243 265 3.2E-7 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 VAPA_1c17660 083bc3232c9f68453cfbc89319e093d8 270 PRINTS PR00412 Epoxide hydrolase signature 50 65 3.2E-7 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 VAPA_1c17660 083bc3232c9f68453cfbc89319e093d8 270 PRINTS PR00412 Epoxide hydrolase signature 211 227 3.2E-7 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 VAPA_1c17660 083bc3232c9f68453cfbc89319e093d8 270 Pfam PF00561 alpha/beta hydrolase fold 24 253 3.4E-26 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 VAPA_1c35390 f78591c9209641fe947cccd28d442ddc 296 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 136 166 - T 12-10-2018 IPR020625 Schiff base-forming aldolase, active site GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|Reactome: R-HSA-389661 VAPA_1c35390 f78591c9209641fe947cccd28d442ddc 296 PIRSF PIRSF001365 2 296 3.1E-91 T 12-10-2018 IPR002220 DapA-like GO:0016829 VAPA_1c35390 f78591c9209641fe947cccd28d442ddc 296 SMART SM01130 3 292 2.4E-141 T 12-10-2018 IPR002220 DapA-like GO:0016829 VAPA_1c35390 f78591c9209641fe947cccd28d442ddc 296 Gene3D G3DSA:3.20.20.70 4 295 3.8E-108 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 VAPA_1c35390 f78591c9209641fe947cccd28d442ddc 296 PRINTS PR00146 Dihydrodipicolinate synthase signature 37 58 1.1E-30 T 12-10-2018 IPR002220 DapA-like GO:0016829 VAPA_1c35390 f78591c9209641fe947cccd28d442ddc 296 PRINTS PR00146 Dihydrodipicolinate synthase signature 131 148 1.1E-30 T 12-10-2018 IPR002220 DapA-like GO:0016829 VAPA_1c35390 f78591c9209641fe947cccd28d442ddc 296 PRINTS PR00146 Dihydrodipicolinate synthase signature 105 121 1.1E-30 T 12-10-2018 IPR002220 DapA-like GO:0016829 VAPA_1c35390 f78591c9209641fe947cccd28d442ddc 296 PRINTS PR00146 Dihydrodipicolinate synthase signature 73 91 1.1E-30 T 12-10-2018 IPR002220 DapA-like GO:0016829 VAPA_1c35390 f78591c9209641fe947cccd28d442ddc 296 Hamap MF_00418 4-hydroxy-tetrahydrodipicolinate synthase [dapA]. 3 290 67.083 T 12-10-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 VAPA_1c35390 f78591c9209641fe947cccd28d442ddc 296 TIGRFAM TIGR00674 dapA: 4-hydroxy-tetrahydrodipicolinate synthase 6 289 2.0E-108 T 12-10-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 VAPA_1c35390 f78591c9209641fe947cccd28d442ddc 296 Pfam PF00701 Dihydrodipicolinate synthetase family 4 290 5.0E-99 T 12-10-2018 IPR002220 DapA-like GO:0016829 VAPA_1c35390 f78591c9209641fe947cccd28d442ddc 296 SUPERFAMILY SSF51569 3 294 2.2E-104 T 12-10-2018 VAPA_1c34610 fcddb060bf46de8107f83d80945008b8 384 TIGRFAM TIGR00203 cydB: cytochrome d ubiquinol oxidase, subunit II 7 382 4.0E-137 T 12-10-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 VAPA_1c34610 fcddb060bf46de8107f83d80945008b8 384 PIRSF PIRSF000267 7 383 3.5E-121 T 12-10-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 VAPA_1c34610 fcddb060bf46de8107f83d80945008b8 384 Pfam PF02322 Cytochrome bd terminal oxidase subunit II 12 366 2.7E-105 T 12-10-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 VAPA_2c00920 ea5ab3f055df392f1a8d9fc3ccaf293c 413 SUPERFAMILY SSF103473 14 413 2.35E-85 T 12-10-2018 IPR036259 MFS transporter superfamily VAPA_2c00920 ea5ab3f055df392f1a8d9fc3ccaf293c 413 Gene3D G3DSA:1.20.1250.20 21 413 3.5E-74 T 12-10-2018 VAPA_2c00920 ea5ab3f055df392f1a8d9fc3ccaf293c 413 Pfam PF07690 Major Facilitator Superfamily 29 366 1.5E-46 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 VAPA_2c00920 ea5ab3f055df392f1a8d9fc3ccaf293c 413 ProSitePatterns PS00217 Sugar transport proteins signature 2. 120 145 - T 12-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 VAPA_1c51420 8361e501f2445476798c6496ab9b5566 362 SUPERFAMILY SSF53850 57 355 6.42E-52 T 12-10-2018 VAPA_1c51420 8361e501f2445476798c6496ab9b5566 362 Pfam PF13343 Bacterial extracellular solute-binding protein 114 331 2.2E-26 T 12-10-2018 VAPA_1c51420 8361e501f2445476798c6496ab9b5566 362 Gene3D G3DSA:3.40.190.10 62 324 1.1E-49 T 12-10-2018 VAPA_1c51420 8361e501f2445476798c6496ab9b5566 362 Gene3D G3DSA:3.40.190.10 152 273 1.1E-49 T 12-10-2018 VAPA_1c42630 b3ba1515643291bce86c86f45b06be93 210 SMART SM00421 146 203 3.0E-17 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_1c42630 b3ba1515643291bce86c86f45b06be93 210 SMART SM00448 2 115 2.1E-26 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_1c42630 b3ba1515643291bce86c86f45b06be93 210 Pfam PF00196 Bacterial regulatory proteins, luxR family 148 203 9.4E-16 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_1c42630 b3ba1515643291bce86c86f45b06be93 210 SUPERFAMILY SSF46894 134 209 2.14E-18 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 VAPA_1c42630 b3ba1515643291bce86c86f45b06be93 210 Gene3D G3DSA:3.40.50.12740 2 209 1.9E-59 T 12-10-2018 VAPA_1c42630 b3ba1515643291bce86c86f45b06be93 210 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 163 179 3.6E-9 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_1c42630 b3ba1515643291bce86c86f45b06be93 210 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 179 191 3.6E-9 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_1c42630 b3ba1515643291bce86c86f45b06be93 210 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 149 163 3.6E-9 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_1c42630 b3ba1515643291bce86c86f45b06be93 210 SUPERFAMILY SSF52172 1 132 4.13E-30 T 12-10-2018 IPR011006 CheY-like superfamily VAPA_1c42630 b3ba1515643291bce86c86f45b06be93 210 ProSitePatterns PS00622 LuxR-type HTH domain signature. 163 190 - T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_1c42630 b3ba1515643291bce86c86f45b06be93 210 Pfam PF00072 Response regulator receiver domain 5 116 1.1E-25 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_1c50350 be4176478dff66a50be6bc1cf70167ea 382 Gene3D G3DSA:3.60.15.10 25 178 4.8E-18 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like VAPA_1c50350 be4176478dff66a50be6bc1cf70167ea 382 TIGRFAM TIGR04122 Xnuc_lig_assoc: putative exonuclease, DNA ligase-associated 17 341 3.7E-151 T 12-10-2018 IPR026360 Putative exonuclease, DNA ligase-associated VAPA_1c50350 be4176478dff66a50be6bc1cf70167ea 382 SUPERFAMILY SSF56281 21 324 2.03E-57 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like VAPA_1c05800 e39846d779830d53a545577ca523563a 272 SUPERFAMILY SSF54001 49 255 6.17E-41 T 12-10-2018 IPR038765 Papain-like cysteine peptidase superfamily VAPA_1c05800 e39846d779830d53a545577ca523563a 272 SMART SM00460 164 230 5.8E-17 T 12-10-2018 IPR002931 Transglutaminase-like VAPA_1c05800 e39846d779830d53a545577ca523563a 272 Gene3D G3DSA:3.10.620.30 81 250 1.4E-70 T 12-10-2018 VAPA_1c05800 e39846d779830d53a545577ca523563a 272 Gene3D G3DSA:2.60.40.2250 12 258 1.4E-70 T 12-10-2018 VAPA_1c05800 e39846d779830d53a545577ca523563a 272 Pfam PF01841 Transglutaminase-like superfamily 135 228 7.7E-20 T 12-10-2018 IPR002931 Transglutaminase-like VAPA_2c02440 751b0508792f8a156d6af3d462bb3803 300 SUPERFAMILY SSF46785 1 85 6.13E-24 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_2c02440 751b0508792f8a156d6af3d462bb3803 300 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 2.7E-22 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_2c02440 751b0508792f8a156d6af3d462bb3803 300 Gene3D G3DSA:3.40.190.290 91 293 7.4E-50 T 12-10-2018 VAPA_2c02440 751b0508792f8a156d6af3d462bb3803 300 SUPERFAMILY SSF53850 88 290 5.1E-41 T 12-10-2018 VAPA_2c02440 751b0508792f8a156d6af3d462bb3803 300 Pfam PF03466 LysR substrate binding domain 88 288 3.0E-40 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_2c02440 751b0508792f8a156d6af3d462bb3803 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 3.3E-11 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_2c02440 751b0508792f8a156d6af3d462bb3803 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 3.3E-11 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_2c02440 751b0508792f8a156d6af3d462bb3803 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 3.3E-11 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_2c02440 751b0508792f8a156d6af3d462bb3803 300 Gene3D G3DSA:1.10.10.10 1 84 1.9E-29 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c09860 901ce348865c20d67659502583b328dd 247 SUPERFAMILY SSF53955 51 243 3.09E-54 T 12-10-2018 IPR023346 Lysozyme-like domain superfamily VAPA_1c09860 901ce348865c20d67659502583b328dd 247 Pfam PF00912 Transglycosylase 58 241 1.2E-50 T 12-10-2018 IPR001264 Glycosyl transferase, family 51 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 VAPA_1c09860 901ce348865c20d67659502583b328dd 247 Gene3D G3DSA:1.10.3810.10 48 246 4.8E-53 T 12-10-2018 IPR036950 Penicillin binding protein transglycosylase domain KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 VAPA_1c09860 901ce348865c20d67659502583b328dd 247 TIGRFAM TIGR02070 mono_pep_trsgly: monofunctional biosynthetic peptidoglycan transglycosylase 7 246 1.4E-71 T 12-10-2018 IPR011812 Biosynthetic peptidoglycan transglycosylase GO:0009252|GO:0009274|GO:0016021|GO:0016763 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 VAPA_1c09860 901ce348865c20d67659502583b328dd 247 Hamap MF_00766 Biosynthetic peptidoglycan transglycosylase [mtgA]. 3 247 36.897 T 12-10-2018 IPR011812 Biosynthetic peptidoglycan transglycosylase GO:0009252|GO:0009274|GO:0016021|GO:0016763 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 VAPA_1c32510 f570811a60c3c338d3bebcb22b19dfa0 323 Gene3D G3DSA:3.10.180.10 155 304 1.3E-34 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase VAPA_1c32510 f570811a60c3c338d3bebcb22b19dfa0 323 SUPERFAMILY SSF54593 1 283 8.63E-33 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase VAPA_1c32510 f570811a60c3c338d3bebcb22b19dfa0 323 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 156 269 1.4E-14 T 12-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain VAPA_1c32510 f570811a60c3c338d3bebcb22b19dfa0 323 Gene3D G3DSA:3.10.180.10 1 122 9.8E-7 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase VAPA_1c45110 362729841a3fffb1b1c3827ce75924eb 614 Gene3D G3DSA:1.25.40.10 434 610 4.6E-28 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 VAPA_1c45110 362729841a3fffb1b1c3827ce75924eb 614 SUPERFAMILY SSF48452 439 599 3.8E-24 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 VAPA_1c45110 362729841a3fffb1b1c3827ce75924eb 614 Gene3D G3DSA:1.25.40.10 101 433 6.0E-16 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 VAPA_1c45110 362729841a3fffb1b1c3827ce75924eb 614 SMART SM00028 499 533 220.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 VAPA_1c45110 362729841a3fffb1b1c3827ce75924eb 614 SMART SM00028 465 498 16.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 VAPA_1c45110 362729841a3fffb1b1c3827ce75924eb 614 SMART SM00028 218 251 57.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 VAPA_1c45110 362729841a3fffb1b1c3827ce75924eb 614 SMART SM00028 319 352 250.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 VAPA_1c45110 362729841a3fffb1b1c3827ce75924eb 614 SMART SM00028 534 567 130.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 VAPA_1c45110 362729841a3fffb1b1c3827ce75924eb 614 SUPERFAMILY SSF48452 272 428 3.52E-8 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 VAPA_1c45110 362729841a3fffb1b1c3827ce75924eb 614 Pfam PF13432 Tetratricopeptide repeat 292 350 0.0022 T 12-10-2018 VAPA_1c45110 362729841a3fffb1b1c3827ce75924eb 614 Pfam PF13432 Tetratricopeptide repeat 469 534 7.9E-7 T 12-10-2018 VAPA_1c02160 ae4533bd9b451d9ab19bf5168b0731b3 213 Pfam PF06684 Amino acid synthesis 4 199 5.9E-71 T 12-10-2018 IPR009569 Amino acid synthesis, putative VAPA_1c02160 ae4533bd9b451d9ab19bf5168b0731b3 213 SUPERFAMILY SSF160519 2 213 6.67E-62 T 12-10-2018 IPR035936 BB2672 superfamily VAPA_1c02160 ae4533bd9b451d9ab19bf5168b0731b3 213 Gene3D G3DSA:3.30.1330.110 1 190 9.2E-53 T 12-10-2018 IPR035936 BB2672 superfamily VAPA_2c00040 25a101d2e85697d96265b88ef9da5cd5 235 Pfam PF00196 Bacterial regulatory proteins, luxR family 173 228 9.8E-16 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_2c00040 25a101d2e85697d96265b88ef9da5cd5 235 Gene3D G3DSA:1.10.10.10 170 235 6.2E-23 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_2c00040 25a101d2e85697d96265b88ef9da5cd5 235 ProSitePatterns PS00622 LuxR-type HTH domain signature. 188 215 - T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_2c00040 25a101d2e85697d96265b88ef9da5cd5 235 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 188 204 1.0E-8 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_2c00040 25a101d2e85697d96265b88ef9da5cd5 235 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 174 188 1.0E-8 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_2c00040 25a101d2e85697d96265b88ef9da5cd5 235 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 204 216 1.0E-8 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_2c00040 25a101d2e85697d96265b88ef9da5cd5 235 Pfam PF03472 Autoinducer binding domain 19 159 4.4E-37 T 12-10-2018 IPR005143 Transcription factor LuxR-like, autoinducer-binding domain VAPA_2c00040 25a101d2e85697d96265b88ef9da5cd5 235 SUPERFAMILY SSF46894 162 234 1.77E-17 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 VAPA_2c00040 25a101d2e85697d96265b88ef9da5cd5 235 Gene3D G3DSA:3.30.450.80 3 169 7.9E-56 T 12-10-2018 IPR036693 Transcription factor LuxR-like, autoinducer-binding domain superfamily VAPA_2c00040 25a101d2e85697d96265b88ef9da5cd5 235 SUPERFAMILY SSF75516 3 166 6.15E-43 T 12-10-2018 IPR036693 Transcription factor LuxR-like, autoinducer-binding domain superfamily VAPA_2c00040 25a101d2e85697d96265b88ef9da5cd5 235 SMART SM00421 171 228 1.7E-16 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_1c11800 3dc0bed8805b8757e4f0d6e0f5934f49 719 SUPERFAMILY SSF56935 36 714 1.37E-115 T 12-10-2018 VAPA_1c11800 3dc0bed8805b8757e4f0d6e0f5934f49 719 Pfam PF00593 TonB dependent receptor 247 714 2.0E-55 T 12-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel VAPA_1c11800 3dc0bed8805b8757e4f0d6e0f5934f49 719 Gene3D G3DSA:2.170.130.10 37 181 2.7E-19 T 12-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily VAPA_1c11800 3dc0bed8805b8757e4f0d6e0f5934f49 719 Gene3D G3DSA:2.40.170.20 194 717 2.8E-95 T 12-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily VAPA_1c11800 3dc0bed8805b8757e4f0d6e0f5934f49 719 Pfam PF07715 TonB-dependent Receptor Plug Domain 59 169 5.7E-19 T 12-10-2018 IPR012910 TonB-dependent receptor, plug domain VAPA_1c51310 ccdd9bc3dc775d99c905ab1eb7b513ec 137 SMART SM00450 14 120 4.2E-12 T 12-10-2018 IPR001763 Rhodanese-like domain VAPA_1c51310 ccdd9bc3dc775d99c905ab1eb7b513ec 137 SUPERFAMILY SSF52821 11 135 3.54E-22 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily VAPA_1c51310 ccdd9bc3dc775d99c905ab1eb7b513ec 137 Gene3D G3DSA:3.40.250.10 8 137 7.7E-30 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily VAPA_1c51310 ccdd9bc3dc775d99c905ab1eb7b513ec 137 Pfam PF00581 Rhodanese-like domain 15 112 4.1E-9 T 12-10-2018 IPR001763 Rhodanese-like domain VAPA_1c19620 15d346e9d6ac5c87fa6235031a137002 307 SUPERFAMILY SSF103481 204 305 4.18E-13 T 12-10-2018 VAPA_1c19620 15d346e9d6ac5c87fa6235031a137002 307 Pfam PF00892 EamA-like transporter family 165 301 3.1E-13 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 VAPA_1c19620 15d346e9d6ac5c87fa6235031a137002 307 Pfam PF00892 EamA-like transporter family 16 143 3.3E-13 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 VAPA_1c19620 15d346e9d6ac5c87fa6235031a137002 307 SUPERFAMILY SSF103481 45 147 1.83E-11 T 12-10-2018 VAPA_1c39670 dcf60f9c96a0aa9497bb06579bf68c21 345 ProSitePatterns PS00211 ABC transporters family signature. 161 175 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_1c39670 dcf60f9c96a0aa9497bb06579bf68c21 345 SUPERFAMILY SSF52540 11 258 5.01E-67 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c39670 dcf60f9c96a0aa9497bb06579bf68c21 345 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 238 325 1.2E-25 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 VAPA_1c39670 dcf60f9c96a0aa9497bb06579bf68c21 345 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 240 307 1.4E-16 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 VAPA_1c39670 dcf60f9c96a0aa9497bb06579bf68c21 345 Gene3D G3DSA:3.40.50.300 8 333 5.0E-92 T 12-10-2018 VAPA_1c39670 dcf60f9c96a0aa9497bb06579bf68c21 345 Pfam PF00005 ABC transporter 38 188 3.0E-27 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c39670 dcf60f9c96a0aa9497bb06579bf68c21 345 SMART SM00382 46 245 9.5E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c27870 121bf44d4523e1185c8f9b0c53895418 298 Pfam PF00491 Arginase family 71 289 7.7E-24 T 12-10-2018 IPR006035 Ureohydrolase GO:0046872 VAPA_1c27870 121bf44d4523e1185c8f9b0c53895418 298 SUPERFAMILY SSF52768 5 289 5.76E-45 T 12-10-2018 IPR023696 Ureohydrolase domain superfamily VAPA_1c27870 121bf44d4523e1185c8f9b0c53895418 298 PRINTS PR00116 Arginase signature 219 248 9.9E-6 T 12-10-2018 IPR006035 Ureohydrolase GO:0046872 VAPA_1c27870 121bf44d4523e1185c8f9b0c53895418 298 PRINTS PR00116 Arginase signature 91 106 9.9E-6 T 12-10-2018 IPR006035 Ureohydrolase GO:0046872 VAPA_1c27870 121bf44d4523e1185c8f9b0c53895418 298 Gene3D G3DSA:3.40.800.10 1 295 8.4E-55 T 12-10-2018 VAPA_1c25240 a9032e1d0474eb3d4d108f74f40b0443 219 Gene3D G3DSA:1.10.10.10 122 218 9.6E-25 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c25240 a9032e1d0474eb3d4d108f74f40b0443 219 Pfam PF00486 Transcriptional regulatory protein, C terminal 145 215 2.4E-19 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 VAPA_1c25240 a9032e1d0474eb3d4d108f74f40b0443 219 Gene3D G3DSA:3.40.50.2300 1 121 2.4E-40 T 12-10-2018 VAPA_1c25240 a9032e1d0474eb3d4d108f74f40b0443 219 Pfam PF00072 Response regulator receiver domain 4 113 9.0E-26 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_1c25240 a9032e1d0474eb3d4d108f74f40b0443 219 SMART SM00448 1 112 3.8E-34 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_1c25240 a9032e1d0474eb3d4d108f74f40b0443 219 SUPERFAMILY SSF52172 1 174 3.84E-37 T 12-10-2018 IPR011006 CheY-like superfamily VAPA_1c25240 a9032e1d0474eb3d4d108f74f40b0443 219 SMART SM00862 145 216 3.8E-21 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 VAPA_1c31600 b1e172c6b7d02ccd16c4b336c584e4b4 199 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 39 196 3.5E-48 T 12-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 VAPA_1c31600 b1e172c6b7d02ccd16c4b336c584e4b4 199 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 153 168 6.4E-11 T 12-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 VAPA_1c31600 b1e172c6b7d02ccd16c4b336c584e4b4 199 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 78 90 6.4E-11 T 12-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 VAPA_1c31600 b1e172c6b7d02ccd16c4b336c584e4b4 199 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 52 67 6.4E-11 T 12-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 VAPA_1c31600 b1e172c6b7d02ccd16c4b336c584e4b4 199 Gene3D G3DSA:2.40.100.10 34 198 2.7E-65 T 12-10-2018 IPR029000 Cyclophilin-like domain superfamily VAPA_1c31600 b1e172c6b7d02ccd16c4b336c584e4b4 199 ProSitePatterns PS00170 Cyclophilin-type peptidyl-prolyl cis-trans isomerase signature. 73 90 - T 12-10-2018 IPR020892 Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site GO:0003755|GO:0006457 VAPA_1c31600 b1e172c6b7d02ccd16c4b336c584e4b4 199 SUPERFAMILY SSF50891 35 197 3.51E-58 T 12-10-2018 IPR029000 Cyclophilin-like domain superfamily VAPA_1c31600 b1e172c6b7d02ccd16c4b336c584e4b4 199 PIRSF PIRSF001467 24 198 8.3E-26 T 12-10-2018 IPR024936 Cyclophilin-type peptidyl-prolyl cis-trans isomerase GO:0003755 VAPA_1c43440 89e0726068377447ec655491a913816c 581 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 402 431 1.2E-60 T 12-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 VAPA_1c43440 89e0726068377447ec655491a913816c 581 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 296 325 1.2E-60 T 12-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 VAPA_1c43440 89e0726068377447ec655491a913816c 581 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 373 400 1.2E-60 T 12-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 VAPA_1c43440 89e0726068377447ec655491a913816c 581 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 7 32 1.2E-60 T 12-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 VAPA_1c43440 89e0726068377447ec655491a913816c 581 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 450 479 1.2E-60 T 12-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 VAPA_1c43440 89e0726068377447ec655491a913816c 581 Pfam PF12729 Four helix bundle sensory module for signal transduction 7 189 1.6E-11 T 12-10-2018 IPR024478 Chemotaxis methyl-accepting receptor HlyB-like, 4HB MCP domain VAPA_1c43440 89e0726068377447ec655491a913816c 581 Gene3D G3DSA:1.10.287.950 231 524 4.8E-90 T 12-10-2018 VAPA_1c43440 89e0726068377447ec655491a913816c 581 SUPERFAMILY SSF58104 252 523 5.49E-73 T 12-10-2018 VAPA_1c43440 89e0726068377447ec655491a913816c 581 SMART SM00283 275 522 2.6E-92 T 12-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 VAPA_1c43440 89e0726068377447ec655491a913816c 581 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 334 490 1.3E-54 T 12-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 VAPA_1c08900 997346fff55782f462da24acfb86e8ab 229 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 36 225 2.4E-16 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 VAPA_1c08900 997346fff55782f462da24acfb86e8ab 229 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 16 120 3.1E-19 T 12-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 VAPA_1c08900 997346fff55782f462da24acfb86e8ab 229 SUPERFAMILY SSF161098 17 220 3.66E-39 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c08900 997346fff55782f462da24acfb86e8ab 229 Gene3D G3DSA:1.10.3720.10 6 226 1.1E-46 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c46090 bfddf4f08d66f6e404f8b65989f6fdaa 401 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 7 399 8.1E-131 T 12-10-2018 IPR002155 Thiolase GO:0016747 VAPA_1c46090 bfddf4f08d66f6e404f8b65989f6fdaa 401 ProSitePatterns PS00737 Thiolases signature 2. 347 363 - T 12-10-2018 IPR020613 Thiolase, conserved site GO:0016747 VAPA_1c46090 bfddf4f08d66f6e404f8b65989f6fdaa 401 SUPERFAMILY SSF53901 277 400 5.76E-45 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 VAPA_1c46090 bfddf4f08d66f6e404f8b65989f6fdaa 401 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 87 105 - T 12-10-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0016747 VAPA_1c46090 bfddf4f08d66f6e404f8b65989f6fdaa 401 Gene3D G3DSA:3.40.47.10 7 282 9.9E-151 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 VAPA_1c46090 bfddf4f08d66f6e404f8b65989f6fdaa 401 ProSitePatterns PS00099 Thiolases active site. 382 395 - T 12-10-2018 IPR020610 Thiolase, active site GO:0016747 VAPA_1c46090 bfddf4f08d66f6e404f8b65989f6fdaa 401 TIGRFAM TIGR02430 pcaF: 3-oxoadipyl-CoA thiolase 4 401 8.7E-212 T 12-10-2018 IPR012793 Beta-ketoadipyl CoA thiolase GO:0016747|GO:0019619 KEGG: 00360+2.3.1.174|KEGG: 00362+2.3.1.174|MetaCyc: PWY-1361|MetaCyc: PWY-2361|MetaCyc: PWY-6185 VAPA_1c46090 bfddf4f08d66f6e404f8b65989f6fdaa 401 SUPERFAMILY SSF53901 5 276 3.4E-77 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 VAPA_1c46090 bfddf4f08d66f6e404f8b65989f6fdaa 401 PIRSF PIRSF000429 1 401 4.9E-128 T 12-10-2018 IPR002155 Thiolase GO:0016747 VAPA_1c46090 bfddf4f08d66f6e404f8b65989f6fdaa 401 Pfam PF00108 Thiolase, N-terminal domain 6 268 4.2E-72 T 12-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 VAPA_1c46090 bfddf4f08d66f6e404f8b65989f6fdaa 401 Pfam PF02803 Thiolase, C-terminal domain 277 400 1.3E-44 T 12-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 VAPA_1c46090 bfddf4f08d66f6e404f8b65989f6fdaa 401 Gene3D G3DSA:3.40.47.10 142 398 9.9E-151 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 VAPA_1c04140 8464d9ee48eeb5e5b6ae516f7abdbb00 262 SUPERFAMILY SSF48452 122 247 1.71E-6 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 VAPA_1c04140 8464d9ee48eeb5e5b6ae516f7abdbb00 262 Gene3D G3DSA:1.25.40.10 90 262 5.6E-10 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 VAPA_1c15090 9a4207ab438d472c38d9756301def675 231 Gene3D G3DSA:3.20.20.70 5 228 1.6E-55 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 VAPA_1c15090 9a4207ab438d472c38d9756301def675 231 SUPERFAMILY SSF51366 7 223 1.73E-46 T 12-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 VAPA_1c15090 9a4207ab438d472c38d9756301def675 231 Hamap MF_00135 N-(5'-phosphoribosyl)anthranilate isomerase [trpF]. 7 225 34.986 T 12-10-2018 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24 VAPA_1c15090 9a4207ab438d472c38d9756301def675 231 Pfam PF00697 N-(5'phosphoribosyl)anthranilate (PRA) isomerase 9 220 1.7E-36 T 12-10-2018 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24 VAPA_1c32080 e5a49143259dd4a63a7e783d3fc0dc26 262 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 26 209 2.2E-43 T 12-10-2018 IPR001303 Class II aldolase/adducin N-terminal VAPA_1c32080 e5a49143259dd4a63a7e783d3fc0dc26 262 SMART SM01007 25 209 1.1E-55 T 12-10-2018 IPR001303 Class II aldolase/adducin N-terminal VAPA_1c32080 e5a49143259dd4a63a7e783d3fc0dc26 262 Gene3D G3DSA:3.40.225.10 10 262 5.7E-74 T 12-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily VAPA_1c32080 e5a49143259dd4a63a7e783d3fc0dc26 262 SUPERFAMILY SSF53639 20 228 3.14E-58 T 12-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily VAPA_1c41950 8ad2a777ba78305d60b8a246defb7d24 217 Pfam PF00510 Cytochrome c oxidase subunit III 34 214 5.7E-17 T 12-10-2018 IPR000298 Cytochrome c oxidase subunit III-like GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 VAPA_1c41950 8ad2a777ba78305d60b8a246defb7d24 217 SUPERFAMILY SSF81452 24 214 1.23E-59 T 12-10-2018 IPR035973 Cytochrome c oxidase subunit III-like superfamily GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 VAPA_1c41950 8ad2a777ba78305d60b8a246defb7d24 217 Gene3D G3DSA:1.20.120.80 31 216 2.2E-58 T 12-10-2018 IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle GO:0004129|GO:0016020|GO:0022904 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 VAPA_1c41950 8ad2a777ba78305d60b8a246defb7d24 217 TIGRFAM TIGR02842 CyoC: cytochrome o ubiquinol oxidase, subunit III 37 215 5.0E-83 T 12-10-2018 IPR014206 Cytochrome o ubiquinol oxidase, subunit III GO:0005886|GO:0008827|GO:0019646 VAPA_1c20840 28d06e45a0b6417db878d59c814de29e 489 Gene3D G3DSA:3.40.605.10 21 478 1.5E-178 T 12-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 VAPA_1c20840 28d06e45a0b6417db878d59c814de29e 489 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 286 297 - T 12-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 VAPA_1c20840 28d06e45a0b6417db878d59c814de29e 489 TIGRFAM TIGR01780 SSADH: succinate-semialdehyde dehydrogenase 31 481 7.5E-198 T 12-10-2018 IPR010102 Succinate semialdehyde dehydrogenase GO:0009013|GO:0009450|GO:0055114 Reactome: R-HSA-916853 VAPA_1c20840 28d06e45a0b6417db878d59c814de29e 489 Gene3D G3DSA:3.40.309.10 265 455 1.5E-178 T 12-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 VAPA_1c20840 28d06e45a0b6417db878d59c814de29e 489 Pfam PF00171 Aldehyde dehydrogenase family 21 483 3.4E-166 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 VAPA_1c20840 28d06e45a0b6417db878d59c814de29e 489 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 258 265 - T 12-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 VAPA_1c20840 28d06e45a0b6417db878d59c814de29e 489 SUPERFAMILY SSF53720 8 485 6.28E-169 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 VAPA_1c41920 ca2f08ab5a9c35afb1b6f1e884346c5a 446 Gene3D G3DSA:1.20.1250.20 36 443 4.5E-36 T 12-10-2018 VAPA_1c41920 ca2f08ab5a9c35afb1b6f1e884346c5a 446 Pfam PF07690 Major Facilitator Superfamily 74 393 3.4E-18 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 VAPA_1c41920 ca2f08ab5a9c35afb1b6f1e884346c5a 446 SUPERFAMILY SSF103473 37 438 1.96E-39 T 12-10-2018 IPR036259 MFS transporter superfamily VAPA_1c41920 ca2f08ab5a9c35afb1b6f1e884346c5a 446 ProSitePatterns PS00216 Sugar transport proteins signature 1. 318 335 - T 12-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 VAPA_2c12540 87a1ac3e3cede2d886e8321555682772 292 Gene3D G3DSA:1.10.3720.10 15 289 6.2E-57 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_2c12540 87a1ac3e3cede2d886e8321555682772 292 SUPERFAMILY SSF161098 12 285 1.4E-53 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_2c12540 87a1ac3e3cede2d886e8321555682772 292 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 111 286 2.6E-6 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 VAPA_1c54260 afb5060449f58e486bd25ed94b6ac622 427 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 7 293 3.0E-24 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 VAPA_1c54260 afb5060449f58e486bd25ed94b6ac622 427 PIRSF PIRSF037495 1 426 4.4E-106 T 12-10-2018 IPR017224 Opine oxidase, subunit A/hydrogen cyanide synthase, subunit B GO:0016491|GO:0055114 VAPA_1c54260 afb5060449f58e486bd25ed94b6ac622 427 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 267 289 7.5E-19 T 12-10-2018 VAPA_1c54260 afb5060449f58e486bd25ed94b6ac622 427 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 8 27 7.5E-19 T 12-10-2018 VAPA_1c54260 afb5060449f58e486bd25ed94b6ac622 427 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 100 118 7.5E-19 T 12-10-2018 VAPA_1c54260 afb5060449f58e486bd25ed94b6ac622 427 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 144 162 7.5E-19 T 12-10-2018 VAPA_1c54260 afb5060449f58e486bd25ed94b6ac622 427 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 236 252 7.5E-19 T 12-10-2018 VAPA_1c54260 afb5060449f58e486bd25ed94b6ac622 427 Gene3D G3DSA:3.50.50.60 7 292 1.5E-40 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c54260 afb5060449f58e486bd25ed94b6ac622 427 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 7 29 8.7E-10 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 VAPA_1c54260 afb5060449f58e486bd25ed94b6ac622 427 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 277 295 8.7E-10 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 VAPA_1c54260 afb5060449f58e486bd25ed94b6ac622 427 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 101 109 8.7E-10 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 VAPA_1c54260 afb5060449f58e486bd25ed94b6ac622 427 SUPERFAMILY SSF51905 4 310 6.48E-34 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c54260 afb5060449f58e486bd25ed94b6ac622 427 Gene3D G3DSA:3.50.50.60 112 244 1.5E-40 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c54260 afb5060449f58e486bd25ed94b6ac622 427 Gene3D G3DSA:1.10.10.1100 340 397 8.0E-10 T 12-10-2018 VAPA_1c10240 a40962c032606d7a94d855dd2756c044 404 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 78 294 4.3E-19 T 12-10-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain VAPA_1c10240 a40962c032606d7a94d855dd2756c044 404 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 52 374 2.6E-75 T 12-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 VAPA_1c10240 a40962c032606d7a94d855dd2756c044 404 Gene3D G3DSA:1.10.287.470 111 184 2.7E-81 T 12-10-2018 VAPA_1c10240 a40962c032606d7a94d855dd2756c044 404 Gene3D G3DSA:2.40.50.100 76 218 2.7E-81 T 12-10-2018 VAPA_1c10240 a40962c032606d7a94d855dd2756c044 404 SUPERFAMILY SSF111369 65 298 1.57E-53 T 12-10-2018 VAPA_1c10240 a40962c032606d7a94d855dd2756c044 404 Gene3D G3DSA:2.40.420.20 305 372 2.7E-81 T 12-10-2018 VAPA_1c10240 a40962c032606d7a94d855dd2756c044 404 Gene3D G3DSA:2.40.30.170 62 304 2.7E-81 T 12-10-2018 VAPA_1c09030 0187e6e8e46a38c3de2076cb799b5c33 402 Gene3D G3DSA:2.40.110.10 119 238 2.1E-36 T 12-10-2018 VAPA_1c09030 0187e6e8e46a38c3de2076cb799b5c33 402 SUPERFAMILY SSF56645 2 247 2.88E-72 T 12-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 VAPA_1c09030 0187e6e8e46a38c3de2076cb799b5c33 402 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 8 120 1.0E-21 T 12-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 VAPA_1c09030 0187e6e8e46a38c3de2076cb799b5c33 402 Gene3D G3DSA:1.20.140.10 239 402 8.6E-37 T 12-10-2018 VAPA_1c09030 0187e6e8e46a38c3de2076cb799b5c33 402 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 125 223 4.1E-20 T 12-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 VAPA_1c09030 0187e6e8e46a38c3de2076cb799b5c33 402 Gene3D G3DSA:1.10.540.10 2 118 4.7E-29 T 12-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 VAPA_1c09030 0187e6e8e46a38c3de2076cb799b5c33 402 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 235 399 1.1E-23 T 12-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 VAPA_1c09030 0187e6e8e46a38c3de2076cb799b5c33 402 SUPERFAMILY SSF47203 235 402 4.83E-25 T 12-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 VAPA_1c51380 02e1c9b7f37f5e9a3890d4e567bc40ae 298 SUPERFAMILY SSF51735 1 157 1.58E-22 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c51380 02e1c9b7f37f5e9a3890d4e567bc40ae 298 Gene3D G3DSA:3.40.50.720 2 171 2.6E-63 T 12-10-2018 VAPA_1c51380 02e1c9b7f37f5e9a3890d4e567bc40ae 298 Pfam PF08546 Ketopantoate reductase PanE/ApbA C terminal 171 294 2.0E-33 T 12-10-2018 IPR013752 Ketopantoate reductase, C-terminal domain VAPA_1c51380 02e1c9b7f37f5e9a3890d4e567bc40ae 298 Pfam PF02558 Ketopantoate reductase PanE/ApbA 3 149 6.6E-41 T 12-10-2018 IPR013332 Ketopantoate reductase, N-terminal domain VAPA_1c51380 02e1c9b7f37f5e9a3890d4e567bc40ae 298 Gene3D G3DSA:1.10.1040.10 172 298 3.2E-42 T 12-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 VAPA_1c51380 02e1c9b7f37f5e9a3890d4e567bc40ae 298 SUPERFAMILY SSF48179 171 294 2.82E-30 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 VAPA_1c51380 02e1c9b7f37f5e9a3890d4e567bc40ae 298 TIGRFAM TIGR00745 apbA_panE: 2-dehydropantoate 2-reductase 2 296 2.4E-82 T 12-10-2018 IPR003710 Ketopantoate reductase ApbA/PanE GO:0005737|GO:0008677|GO:0015940 KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654 VAPA_1c01380 6e08fd22f4a6cc9e46c3a9c9422b70ff 296 Pfam PF05853 beta-keto acid cleavage enzyme 5 291 1.8E-97 T 12-10-2018 IPR008567 3-keto-5-aminohexanoate cleavage enzyme GO:0016740|GO:0019475 KEGG: 00310+2.3.1.247 VAPA_1c01380 6e08fd22f4a6cc9e46c3a9c9422b70ff 296 Gene3D G3DSA:3.20.20.70 3 294 1.0E-107 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 VAPA_1c15950 3e952b8fd05be48f8aa3598a466d863a 155 Pfam PF00866 Ring hydroxylating beta subunit 11 144 8.5E-26 T 12-10-2018 IPR000391 Ring-hydroxylating dioxygenase beta subunit GO:0006725|GO:0055114 VAPA_1c15950 3e952b8fd05be48f8aa3598a466d863a 155 SUPERFAMILY SSF54427 7 154 1.78E-40 T 12-10-2018 IPR032710 NTF2-like domain superfamily VAPA_1c15950 3e952b8fd05be48f8aa3598a466d863a 155 Gene3D G3DSA:3.10.450.50 2 154 2.0E-40 T 12-10-2018 VAPA_1c10210 cfc0823d5480ba14295980088ddfe2c2 475 Gene3D G3DSA:1.10.287.130 199 315 1.8E-15 T 12-10-2018 VAPA_1c10210 cfc0823d5480ba14295980088ddfe2c2 475 SMART SM00387 364 475 5.7E-34 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase VAPA_1c10210 cfc0823d5480ba14295980088ddfe2c2 475 SUPERFAMILY SSF47384 235 314 1.02E-12 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 VAPA_1c10210 cfc0823d5480ba14295980088ddfe2c2 475 SMART SM00388 252 320 1.2E-9 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 VAPA_1c10210 cfc0823d5480ba14295980088ddfe2c2 475 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 365 474 4.9E-18 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase VAPA_1c10210 cfc0823d5480ba14295980088ddfe2c2 475 SUPERFAMILY SSF55874 311 473 1.44E-35 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_1c10210 cfc0823d5480ba14295980088ddfe2c2 475 PRINTS PR00344 Bacterial sensor protein C-terminal signature 459 472 5.9E-16 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c10210 cfc0823d5480ba14295980088ddfe2c2 475 PRINTS PR00344 Bacterial sensor protein C-terminal signature 419 429 5.9E-16 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c10210 cfc0823d5480ba14295980088ddfe2c2 475 PRINTS PR00344 Bacterial sensor protein C-terminal signature 436 454 5.9E-16 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c10210 cfc0823d5480ba14295980088ddfe2c2 475 PRINTS PR00344 Bacterial sensor protein C-terminal signature 401 415 5.9E-16 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c10210 cfc0823d5480ba14295980088ddfe2c2 475 Pfam PF00512 His Kinase A (phospho-acceptor) domain 253 314 1.0E-8 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 VAPA_1c10210 cfc0823d5480ba14295980088ddfe2c2 475 Gene3D G3DSA:3.30.565.10 316 473 8.1E-36 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_1c17210 acd16654161a7087ebf5714c1f67987e 420 Gene3D G3DSA:2.150.10.10 190 327 1.5E-10 T 12-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal VAPA_1c00350 8355c5fe3651a31123e0c5cd4d16a7f0 292 Gene3D G3DSA:3.40.50.1820 13 273 1.5E-33 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c00350 8355c5fe3651a31123e0c5cd4d16a7f0 292 SUPERFAMILY SSF53474 15 271 1.11E-24 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c00350 8355c5fe3651a31123e0c5cd4d16a7f0 292 Pfam PF12146 Serine aminopeptidase, S33 19 259 2.3E-12 T 12-10-2018 IPR022742 Serine aminopeptidase, S33 VAPA_2c11100 239e6358806b722b5267c301398ec925 330 SUPERFAMILY SSF53850 123 291 1.47E-10 T 12-10-2018 VAPA_2c11100 239e6358806b722b5267c301398ec925 330 Gene3D G3DSA:3.40.190.10 133 253 2.7E-98 T 12-10-2018 VAPA_2c11100 239e6358806b722b5267c301398ec925 330 Gene3D G3DSA:3.40.190.150 34 318 2.7E-98 T 12-10-2018 VAPA_2c11100 239e6358806b722b5267c301398ec925 330 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 54 320 9.4E-77 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_2c11100 239e6358806b722b5267c301398ec925 330 PIRSF PIRSF017082 1 326 2.2E-78 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c20720 13613d44ab129d80ea070d629415970f 144 SUPERFAMILY SSF52788 2 140 9.94E-43 T 12-10-2018 IPR036196 Phosphotyrosine protein phosphatase I superfamily VAPA_1c20720 13613d44ab129d80ea070d629415970f 144 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 4 21 4.3E-17 T 12-10-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 VAPA_1c20720 13613d44ab129d80ea070d629415970f 144 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 40 56 4.3E-17 T 12-10-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 VAPA_1c20720 13613d44ab129d80ea070d629415970f 144 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 74 89 4.3E-17 T 12-10-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 VAPA_1c20720 13613d44ab129d80ea070d629415970f 144 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 111 126 4.3E-17 T 12-10-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 VAPA_1c20720 13613d44ab129d80ea070d629415970f 144 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 4 136 3.9E-36 T 12-10-2018 IPR023485 Phosphotyrosine protein phosphatase I VAPA_1c20720 13613d44ab129d80ea070d629415970f 144 SMART SM00226 2 139 2.1E-48 T 12-10-2018 IPR023485 Phosphotyrosine protein phosphatase I VAPA_1c20720 13613d44ab129d80ea070d629415970f 144 Gene3D G3DSA:3.40.50.2300 1 144 1.2E-47 T 12-10-2018 VAPA_1c50250 c6c575fb8b7200fbe586b612a86a6154 297 Gene3D G3DSA:1.10.3720.10 21 294 6.4E-57 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c50250 c6c575fb8b7200fbe586b612a86a6154 297 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 112 291 5.3E-11 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 VAPA_1c50250 c6c575fb8b7200fbe586b612a86a6154 297 SUPERFAMILY SSF161098 16 291 2.06E-58 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c42310 ceeeadebab6e423b54624e76ee05edaa 262 Gene3D G3DSA:2.60.120.620 8 240 2.0E-13 T 12-10-2018 VAPA_1c42310 ceeeadebab6e423b54624e76ee05edaa 262 SUPERFAMILY SSF51197 15 238 4.12E-22 T 12-10-2018 VAPA_1c42310 ceeeadebab6e423b54624e76ee05edaa 262 Pfam PF05721 Phytanoyl-CoA dioxygenase (PhyH) 97 230 9.6E-6 T 12-10-2018 IPR008775 Phytanoyl-CoA dioxygenase VAPA_1c37720 6a335e3411d88ba628688b60c302b41e 424 SUPERFAMILY SSF103473 23 412 3.14E-34 T 12-10-2018 IPR036259 MFS transporter superfamily VAPA_1c37720 6a335e3411d88ba628688b60c302b41e 424 Gene3D G3DSA:1.20.1250.20 20 403 1.4E-28 T 12-10-2018 VAPA_1c37720 6a335e3411d88ba628688b60c302b41e 424 Pfam PF05977 Transmembrane secretion effector 24 400 1.2E-35 T 12-10-2018 IPR010290 Transmembrane secretion effector VAPA_2c01040 476c9e81aec9f04c0b69f2c7baca87f1 129 Pfam PF12172 Rubredoxin-like zinc ribbon domain (DUF35_N) 16 49 1.3E-12 T 12-10-2018 IPR022002 Domain of unknown function DUF35, rubredoxin-like zinc ribbon domain, N-terminal VAPA_2c01040 476c9e81aec9f04c0b69f2c7baca87f1 129 Pfam PF01796 DUF35 OB-fold domain, acyl-CoA-associated 50 109 6.2E-15 T 12-10-2018 IPR002878 Domain of unknown function DUF35, OB-fold, C-terminal VAPA_2c01040 476c9e81aec9f04c0b69f2c7baca87f1 129 SUPERFAMILY SSF50249 10 115 8.57E-28 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold VAPA_2c12690 80a3f3aea5dbced18232d5ec33f51ac1 108 Pfam PF13560 Helix-turn-helix domain 30 84 1.5E-12 T 12-10-2018 VAPA_2c12690 80a3f3aea5dbced18232d5ec33f51ac1 108 SMART SM00530 33 88 1.3E-5 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 VAPA_2c12690 80a3f3aea5dbced18232d5ec33f51ac1 108 Gene3D G3DSA:1.10.260.40 25 96 8.5E-18 T 12-10-2018 VAPA_2c12690 80a3f3aea5dbced18232d5ec33f51ac1 108 SUPERFAMILY SSF47413 29 87 1.65E-10 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 VAPA_1c21730 b4d903030503a3eabc857295004f0d79 457 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 436 456 1.4E-49 T 12-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 VAPA_1c21730 b4d903030503a3eabc857295004f0d79 457 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 321 342 1.4E-49 T 12-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 VAPA_1c21730 b4d903030503a3eabc857295004f0d79 457 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 46 69 1.4E-49 T 12-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 VAPA_1c21730 b4d903030503a3eabc857295004f0d79 457 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 88 108 1.4E-49 T 12-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 VAPA_1c21730 b4d903030503a3eabc857295004f0d79 457 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 378 401 1.4E-49 T 12-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 VAPA_1c21730 b4d903030503a3eabc857295004f0d79 457 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 354 378 1.4E-49 T 12-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 VAPA_1c21730 b4d903030503a3eabc857295004f0d79 457 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 421 436 1.4E-49 T 12-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 VAPA_1c21730 b4d903030503a3eabc857295004f0d79 457 Pfam PF13533 Biotin-lipoyl like 80 112 2.8E-6 T 12-10-2018 IPR039562 Membrane fusion protein, biotin-lipoyl like domain VAPA_1c21730 b4d903030503a3eabc857295004f0d79 457 Gene3D G3DSA:2.40.30.170 346 434 1.1E-13 T 12-10-2018 VAPA_1c21730 b4d903030503a3eabc857295004f0d79 457 SUPERFAMILY SSF111369 79 128 3.53E-6 T 12-10-2018 VAPA_1c21730 b4d903030503a3eabc857295004f0d79 457 Pfam PF13437 HlyD family secretion protein 309 410 1.4E-13 T 12-10-2018 VAPA_1c21730 b4d903030503a3eabc857295004f0d79 457 Gene3D G3DSA:2.40.50.100 309 345 1.1E-13 T 12-10-2018 VAPA_1c21730 b4d903030503a3eabc857295004f0d79 457 Gene3D G3DSA:2.40.50.100 76 109 9.5E-9 T 12-10-2018 VAPA_1c21730 b4d903030503a3eabc857295004f0d79 457 TIGRFAM TIGR01843 type_I_hlyD: type I secretion membrane fusion protein, HlyD family 36 457 2.5E-105 T 12-10-2018 IPR010129 Type I secretion membrane fusion protein, HlyD family GO:0015031|GO:0016021 VAPA_1c21730 b4d903030503a3eabc857295004f0d79 457 Gene3D G3DSA:1.10.287.470 232 308 1.1E-13 T 12-10-2018 VAPA_1c21730 b4d903030503a3eabc857295004f0d79 457 Gene3D G3DSA:1.10.287.470 110 198 9.5E-9 T 12-10-2018 VAPA_1c31210 4f3a541f3c0aa06a2518cf588cc5a81c 254 TIGRFAM TIGR02111 PQQ_syn_pqqC: coenzyme PQQ biosynthesis protein C 25 252 9.5E-106 T 12-10-2018 IPR011845 Coenzyme PQQ biosynthesis protein C GO:0018189|GO:0055114 MetaCyc: PWY-6420 VAPA_1c31210 4f3a541f3c0aa06a2518cf588cc5a81c 254 Gene3D G3DSA:1.20.910.10 21 253 5.5E-68 T 12-10-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 VAPA_1c31210 4f3a541f3c0aa06a2518cf588cc5a81c 254 Pfam PF03070 TENA/THI-4/PQQC family 30 243 7.2E-57 T 12-10-2018 IPR004305 Thiaminase-2/PQQC VAPA_1c31210 4f3a541f3c0aa06a2518cf588cc5a81c 254 SUPERFAMILY SSF48613 22 250 3.21E-71 T 12-10-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 VAPA_1c31210 4f3a541f3c0aa06a2518cf588cc5a81c 254 Hamap MF_00654 Pyrroloquinoline-quinone synthase [pqqC]. 1 254 124.781 T 12-10-2018 IPR011845 Coenzyme PQQ biosynthesis protein C GO:0018189|GO:0055114 MetaCyc: PWY-6420 VAPA_1c00630 05839b8ca011df5e3c1888a27b4d740a 305 Pfam PF12146 Serine aminopeptidase, S33 96 205 2.2E-8 T 12-10-2018 IPR022742 Serine aminopeptidase, S33 VAPA_1c00630 05839b8ca011df5e3c1888a27b4d740a 305 SUPERFAMILY SSF53474 86 304 5.84E-30 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c00630 05839b8ca011df5e3c1888a27b4d740a 305 Gene3D G3DSA:3.40.50.1820 81 304 1.5E-28 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c41740 07438e350a7ff921ff3ec3b07c44067d 468 SUPERFAMILY SSF47384 221 302 4.71E-13 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 VAPA_1c41740 07438e350a7ff921ff3ec3b07c44067d 468 SMART SM00388 238 301 2.3E-10 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 VAPA_1c41740 07438e350a7ff921ff3ec3b07c44067d 468 Pfam PF00512 His Kinase A (phospho-acceptor) domain 238 301 1.8E-9 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 VAPA_1c41740 07438e350a7ff921ff3ec3b07c44067d 468 SUPERFAMILY SSF55874 291 451 3.67E-35 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_1c41740 07438e350a7ff921ff3ec3b07c44067d 468 PRINTS PR00344 Bacterial sensor protein C-terminal signature 415 433 1.8E-8 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c41740 07438e350a7ff921ff3ec3b07c44067d 468 PRINTS PR00344 Bacterial sensor protein C-terminal signature 439 452 1.8E-8 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c41740 07438e350a7ff921ff3ec3b07c44067d 468 PRINTS PR00344 Bacterial sensor protein C-terminal signature 381 395 1.8E-8 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c41740 07438e350a7ff921ff3ec3b07c44067d 468 SMART SM00387 345 455 2.2E-26 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase VAPA_1c41740 07438e350a7ff921ff3ec3b07c44067d 468 Gene3D G3DSA:3.30.565.10 302 456 9.5E-33 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_1c41740 07438e350a7ff921ff3ec3b07c44067d 468 Gene3D G3DSA:1.10.287.130 224 301 5.5E-11 T 12-10-2018 VAPA_1c41740 07438e350a7ff921ff3ec3b07c44067d 468 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 345 452 6.1E-18 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase VAPA_1c18710 ce61984ef03636ae177b6ced534dcc09 315 SUPERFAMILY SSF46785 1 111 1.63E-16 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c18710 ce61984ef03636ae177b6ced534dcc09 315 Pfam PF03466 LysR substrate binding domain 87 301 1.8E-32 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_1c18710 ce61984ef03636ae177b6ced534dcc09 315 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 62 9.2E-14 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c18710 ce61984ef03636ae177b6ced534dcc09 315 Gene3D G3DSA:3.40.190.290 90 301 4.1E-55 T 12-10-2018 VAPA_1c18710 ce61984ef03636ae177b6ced534dcc09 315 Gene3D G3DSA:1.10.10.10 1 88 1.3E-18 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c18710 ce61984ef03636ae177b6ced534dcc09 315 SUPERFAMILY SSF53850 88 306 9.91E-38 T 12-10-2018 VAPA_1c12150 4fef1006c549ecaba6ce8a52bff45886 163 TIGRFAM TIGR04430 OM_asym_MlaD: outer membrane lipid asymmetry maintenance protein MlaD 3 147 5.4E-59 T 12-10-2018 IPR030970 Probable phospholipid ABC transporter-binding protein MlaD GO:0015914 VAPA_1c12150 4fef1006c549ecaba6ce8a52bff45886 163 Pfam PF02470 MlaD protein 39 116 2.1E-20 T 12-10-2018 IPR003399 Mce/MlaD VAPA_1c03020 aeafaca028a151b893ccbf89d1036ad9 1444 Gene3D G3DSA:2.180.10.10 995 1312 3.9E-33 T 12-10-2018 VAPA_1c03020 aeafaca028a151b893ccbf89d1036ad9 1444 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 720 761 8.3E-6 T 12-10-2018 IPR006530 YD repeat VAPA_1c03020 aeafaca028a151b893ccbf89d1036ad9 1444 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 552 588 3.0E-5 T 12-10-2018 IPR006530 YD repeat VAPA_1c03020 aeafaca028a151b893ccbf89d1036ad9 1444 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 678 714 1.1E-7 T 12-10-2018 IPR006530 YD repeat VAPA_1c03020 aeafaca028a151b893ccbf89d1036ad9 1444 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 762 803 1.4E-8 T 12-10-2018 IPR006530 YD repeat VAPA_1c03020 aeafaca028a151b893ccbf89d1036ad9 1444 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 636 677 3.0E-4 T 12-10-2018 IPR006530 YD repeat VAPA_1c03020 aeafaca028a151b893ccbf89d1036ad9 1444 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 594 635 3.6E-6 T 12-10-2018 IPR006530 YD repeat VAPA_1c03020 aeafaca028a151b893ccbf89d1036ad9 1444 Pfam PF05593 RHS Repeat 594 630 8.2E-5 T 12-10-2018 IPR031325 RHS repeat VAPA_1c03020 aeafaca028a151b893ccbf89d1036ad9 1444 Pfam PF05593 RHS Repeat 678 713 2.8E-7 T 12-10-2018 IPR031325 RHS repeat VAPA_1c03020 aeafaca028a151b893ccbf89d1036ad9 1444 Pfam PF05593 RHS Repeat 980 1016 1.6E-6 T 12-10-2018 IPR031325 RHS repeat VAPA_1c03020 aeafaca028a151b893ccbf89d1036ad9 1444 Pfam PF05593 RHS Repeat 700 735 5.1E-5 T 12-10-2018 IPR031325 RHS repeat VAPA_1c03020 aeafaca028a151b893ccbf89d1036ad9 1444 Pfam PF05593 RHS Repeat 657 693 3.7E-5 T 12-10-2018 IPR031325 RHS repeat VAPA_1c03020 aeafaca028a151b893ccbf89d1036ad9 1444 Pfam PF05593 RHS Repeat 552 589 2.1E-8 T 12-10-2018 IPR031325 RHS repeat VAPA_1c03020 aeafaca028a151b893ccbf89d1036ad9 1444 Gene3D G3DSA:3.90.930.1 581 746 8.3E-9 T 12-10-2018 VAPA_1c03020 aeafaca028a151b893ccbf89d1036ad9 1444 Gene3D G3DSA:3.90.930.1 797 921 2.8E-5 T 12-10-2018 VAPA_1c03020 aeafaca028a151b893ccbf89d1036ad9 1444 Pfam PF03527 RHS protein 1209 1244 1.7E-11 T 12-10-2018 IPR001826 RHS protein VAPA_1c03020 aeafaca028a151b893ccbf89d1036ad9 1444 PRINTS PR00394 RHS protein signature 1280 1299 2.4E-14 T 12-10-2018 IPR001826 RHS protein VAPA_1c03020 aeafaca028a151b893ccbf89d1036ad9 1444 PRINTS PR00394 RHS protein signature 1257 1277 2.4E-14 T 12-10-2018 IPR001826 RHS protein VAPA_1c03020 aeafaca028a151b893ccbf89d1036ad9 1444 PRINTS PR00394 RHS protein signature 1203 1223 2.4E-14 T 12-10-2018 IPR001826 RHS protein VAPA_1c03020 aeafaca028a151b893ccbf89d1036ad9 1444 TIGRFAM TIGR03696 Rhs_assc_core: RHS repeat-associated core domain 1239 1312 8.5E-23 T 12-10-2018 IPR022385 Rhs repeat-associated core GO:0097264 VAPA_1c22400 bf76d283dfcf3802c7db8f624d86c7a4 161 SUPERFAMILY SSF54427 5 160 1.13E-45 T 12-10-2018 IPR032710 NTF2-like domain superfamily VAPA_1c22400 bf76d283dfcf3802c7db8f624d86c7a4 161 Pfam PF00866 Ring hydroxylating beta subunit 18 150 1.8E-28 T 12-10-2018 IPR000391 Ring-hydroxylating dioxygenase beta subunit GO:0006725|GO:0055114 VAPA_1c22400 bf76d283dfcf3802c7db8f624d86c7a4 161 Gene3D G3DSA:3.10.450.50 4 161 8.0E-46 T 12-10-2018 VAPA_2c12780 8fdc6ae598667117b1517866617e53f9 320 Pfam PF08401 Domain of unknown function (DUF1738) 8 110 4.3E-27 T 12-10-2018 IPR013610 Domain of unknown function DUF1738 VAPA_2c12780 8fdc6ae598667117b1517866617e53f9 320 PIRSF PIRSF037112 2 313 1.7E-82 T 12-10-2018 IPR017113 Antirestriction, ArdC VAPA_1c49140 ef7983a909e519aa70932731918f1314 328 Gene3D G3DSA:3.40.190.10 34 320 6.9E-55 T 12-10-2018 VAPA_1c49140 ef7983a909e519aa70932731918f1314 328 Gene3D G3DSA:3.40.190.10 111 205 6.9E-55 T 12-10-2018 VAPA_1c49140 ef7983a909e519aa70932731918f1314 328 SUPERFAMILY SSF53850 27 253 5.0E-24 T 12-10-2018 VAPA_1c49140 ef7983a909e519aa70932731918f1314 328 Pfam PF09084 NMT1/THI5 like 39 244 1.1E-31 T 12-10-2018 IPR015168 SsuA/THI5-like VAPA_1c48090 e7809dd2d9443079326284983cd1fa49 207 SUPERFAMILY SSF51206 3 118 7.2E-15 T 12-10-2018 IPR018490 Cyclic nucleotide-binding-like VAPA_1c48090 e7809dd2d9443079326284983cd1fa49 207 SUPERFAMILY SSF46785 123 203 2.68E-19 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c48090 e7809dd2d9443079326284983cd1fa49 207 SMART SM00419 145 193 3.6E-6 T 12-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 VAPA_1c48090 e7809dd2d9443079326284983cd1fa49 207 Pfam PF00027 Cyclic nucleotide-binding domain 7 93 5.4E-7 T 12-10-2018 IPR000595 Cyclic nucleotide-binding domain VAPA_1c48090 e7809dd2d9443079326284983cd1fa49 207 Pfam PF13545 Crp-like helix-turn-helix domain 126 199 8.7E-16 T 12-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 VAPA_1c48090 e7809dd2d9443079326284983cd1fa49 207 Gene3D G3DSA:2.60.120.10 1 108 9.0E-12 T 12-10-2018 IPR014710 RmlC-like jelly roll fold VAPA_1c48090 e7809dd2d9443079326284983cd1fa49 207 Gene3D G3DSA:1.10.10.10 123 201 5.6E-22 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c12420 a1f92c7259db492f8c9ff6e261862b26 386 Pfam PF13365 Trypsin-like peptidase domain 106 240 1.5E-33 T 12-10-2018 VAPA_1c12420 a1f92c7259db492f8c9ff6e261862b26 386 PRINTS PR00834 HtrA/DegQ protease family signature 136 156 1.7E-52 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 VAPA_1c12420 a1f92c7259db492f8c9ff6e261862b26 386 PRINTS PR00834 HtrA/DegQ protease family signature 115 127 1.7E-52 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 VAPA_1c12420 a1f92c7259db492f8c9ff6e261862b26 386 PRINTS PR00834 HtrA/DegQ protease family signature 211 228 1.7E-52 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 VAPA_1c12420 a1f92c7259db492f8c9ff6e261862b26 386 PRINTS PR00834 HtrA/DegQ protease family signature 319 331 1.7E-52 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 VAPA_1c12420 a1f92c7259db492f8c9ff6e261862b26 386 PRINTS PR00834 HtrA/DegQ protease family signature 176 200 1.7E-52 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 VAPA_1c12420 a1f92c7259db492f8c9ff6e261862b26 386 PRINTS PR00834 HtrA/DegQ protease family signature 233 250 1.7E-52 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 VAPA_1c12420 a1f92c7259db492f8c9ff6e261862b26 386 SUPERFAMILY SSF50156 238 360 1.2E-20 T 12-10-2018 IPR036034 PDZ superfamily GO:0005515 VAPA_1c12420 a1f92c7259db492f8c9ff6e261862b26 386 Gene3D G3DSA:2.40.10.120 57 272 6.5E-80 T 12-10-2018 VAPA_1c12420 a1f92c7259db492f8c9ff6e261862b26 386 Pfam PF13180 PDZ domain 280 369 6.3E-14 T 12-10-2018 IPR001478 PDZ domain GO:0005515 VAPA_1c12420 a1f92c7259db492f8c9ff6e261862b26 386 Gene3D G3DSA:2.30.42.10 274 376 6.5E-26 T 12-10-2018 VAPA_1c12420 a1f92c7259db492f8c9ff6e261862b26 386 SUPERFAMILY SSF50494 58 276 3.6E-65 T 12-10-2018 IPR009003 Peptidase S1, PA clan VAPA_1c12420 a1f92c7259db492f8c9ff6e261862b26 386 SMART SM00228 279 361 5.3E-9 T 12-10-2018 IPR001478 PDZ domain GO:0005515 VAPA_1c06060 e9c2cf050379d246db0524c3b2cb27bf 444 Gene3D G3DSA:1.25.40.10 13 113 9.7E-17 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 VAPA_1c06060 e9c2cf050379d246db0524c3b2cb27bf 444 SUPERFAMILY SSF48452 17 220 3.41E-28 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 VAPA_1c06060 e9c2cf050379d246db0524c3b2cb27bf 444 Gene3D G3DSA:3.40.50.150 240 428 4.0E-27 T 12-10-2018 VAPA_1c06060 e9c2cf050379d246db0524c3b2cb27bf 444 Pfam PF08241 Methyltransferase domain 286 378 7.0E-14 T 12-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 VAPA_1c06060 e9c2cf050379d246db0524c3b2cb27bf 444 Gene3D G3DSA:1.25.40.10 114 233 1.6E-18 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 VAPA_1c06060 e9c2cf050379d246db0524c3b2cb27bf 444 SUPERFAMILY SSF53335 242 425 7.37E-30 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase VAPA_1c06060 e9c2cf050379d246db0524c3b2cb27bf 444 SMART SM00028 118 151 1.6 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 VAPA_1c06060 e9c2cf050379d246db0524c3b2cb27bf 444 SMART SM00028 152 185 5.1 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 VAPA_1c06060 e9c2cf050379d246db0524c3b2cb27bf 444 SMART SM00028 186 219 130.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 VAPA_1c06060 e9c2cf050379d246db0524c3b2cb27bf 444 SMART SM00028 47 80 25.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 VAPA_1c06060 e9c2cf050379d246db0524c3b2cb27bf 444 SMART SM00028 81 114 15.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 VAPA_1c06060 e9c2cf050379d246db0524c3b2cb27bf 444 Pfam PF13432 Tetratricopeptide repeat 59 106 0.012 T 12-10-2018 VAPA_1c06060 e9c2cf050379d246db0524c3b2cb27bf 444 Pfam PF13432 Tetratricopeptide repeat 125 178 2.0E-4 T 12-10-2018 VAPA_1c28660 87f6738fd98371d82bf0a78c314ce6d4 267 Pfam PF01553 Acyltransferase 82 195 1.2E-12 T 12-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 VAPA_1c28660 87f6738fd98371d82bf0a78c314ce6d4 267 SMART SM00563 90 198 2.2E-20 T 12-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 VAPA_1c28660 87f6738fd98371d82bf0a78c314ce6d4 267 SUPERFAMILY SSF69593 29 249 4.32E-23 T 12-10-2018 VAPA_1c40650 33ddebeefb3adf687a7ab1425dcaf329 297 Gene3D G3DSA:3.40.190.10 26 272 6.3E-87 T 12-10-2018 VAPA_1c40650 33ddebeefb3adf687a7ab1425dcaf329 297 SMART SM00062 36 269 1.2E-47 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF VAPA_1c40650 33ddebeefb3adf687a7ab1425dcaf329 297 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 37 266 4.3E-50 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF VAPA_1c40650 33ddebeefb3adf687a7ab1425dcaf329 297 Gene3D G3DSA:3.40.190.10 131 226 6.3E-87 T 12-10-2018 VAPA_1c40650 33ddebeefb3adf687a7ab1425dcaf329 297 SUPERFAMILY SSF53850 5 270 2.21E-57 T 12-10-2018 VAPA_1c21740 9c4650ac567ead80eb559256cf0fc57b 444 SUPERFAMILY SSF56954 3 430 1.44E-82 T 12-10-2018 VAPA_1c21740 9c4650ac567ead80eb559256cf0fc57b 444 Gene3D G3DSA:1.20.1600.10 24 444 5.1E-95 T 12-10-2018 VAPA_1c21740 9c4650ac567ead80eb559256cf0fc57b 444 TIGRFAM TIGR01844 type_I_sec_TolC: type I secretion outer membrane protein, TolC family 23 428 7.2E-90 T 12-10-2018 IPR010130 Type I secretion outer membrane protein, TolC GO:0015562|GO:0019867|GO:0055085 VAPA_1c21740 9c4650ac567ead80eb559256cf0fc57b 444 Pfam PF02321 Outer membrane efflux protein 25 218 7.9E-24 T 12-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 VAPA_1c21740 9c4650ac567ead80eb559256cf0fc57b 444 Pfam PF02321 Outer membrane efflux protein 242 428 8.3E-27 T 12-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 VAPA_1c54170 7c5da48d1f719f92ffbcadded9d1fed1 501 SMART SM00345 37 96 3.1E-15 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_1c54170 7c5da48d1f719f92ffbcadded9d1fed1 501 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 56 70 6.5E-6 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_1c54170 7c5da48d1f719f92ffbcadded9d1fed1 501 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 70 86 6.5E-6 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_1c54170 7c5da48d1f719f92ffbcadded9d1fed1 501 Gene3D G3DSA:1.10.10.10 28 100 4.7E-20 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c54170 7c5da48d1f719f92ffbcadded9d1fed1 501 Pfam PF00392 Bacterial regulatory proteins, gntR family 36 96 6.1E-15 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_1c54170 7c5da48d1f719f92ffbcadded9d1fed1 501 SUPERFAMILY SSF53383 139 501 1.66E-83 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase VAPA_1c54170 7c5da48d1f719f92ffbcadded9d1fed1 501 SUPERFAMILY SSF46785 29 99 2.72E-19 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c54170 7c5da48d1f719f92ffbcadded9d1fed1 501 Gene3D G3DSA:3.40.640.10 131 496 4.9E-116 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 VAPA_1c54170 7c5da48d1f719f92ffbcadded9d1fed1 501 Pfam PF00155 Aminotransferase class I and II 173 434 1.2E-21 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 VAPA_1c20180 24c40c0ffd386dc28bdc2daa9e7c5114 301 SUPERFAMILY SSF53659 237 290 4.45E-6 T 12-10-2018 VAPA_1c20180 24c40c0ffd386dc28bdc2daa9e7c5114 301 Pfam PF01609 Transposase DDE domain 70 152 6.6E-6 T 12-10-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 VAPA_1c20180 24c40c0ffd386dc28bdc2daa9e7c5114 301 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 237 286 7.0E-5 T 12-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 VAPA_1c20180 24c40c0ffd386dc28bdc2daa9e7c5114 301 SUPERFAMILY SSF53098 54 161 1.29E-10 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily VAPA_1c20180 24c40c0ffd386dc28bdc2daa9e7c5114 301 Gene3D G3DSA:3.40.718.10 233 292 7.2E-6 T 12-10-2018 VAPA_1c43470 d67b0283f9bbd7a163eb3d267bbe37ef 169 Pfam PF01584 CheW-like domain 23 159 4.4E-37 T 12-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 VAPA_1c43470 d67b0283f9bbd7a163eb3d267bbe37ef 169 SMART SM00260 19 156 2.5E-41 T 12-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 VAPA_1c43470 d67b0283f9bbd7a163eb3d267bbe37ef 169 Gene3D G3DSA:2.40.50.180 42 151 1.5E-40 T 12-10-2018 VAPA_1c43470 d67b0283f9bbd7a163eb3d267bbe37ef 169 Gene3D G3DSA:2.30.30.40 25 150 1.5E-40 T 12-10-2018 VAPA_1c43470 d67b0283f9bbd7a163eb3d267bbe37ef 169 SUPERFAMILY SSF50341 16 161 6.28E-40 T 12-10-2018 IPR036061 CheW-like domain superfamily GO:0006935|GO:0007165 VAPA_1c11440 44456b5a18645230bb3507bc7e6a4ea1 421 SUPERFAMILY SSF53187 17 400 4.89E-78 T 12-10-2018 VAPA_1c11440 44456b5a18645230bb3507bc7e6a4ea1 421 Gene3D G3DSA:3.40.630.10 27 387 1.8E-126 T 12-10-2018 VAPA_1c11440 44456b5a18645230bb3507bc7e6a4ea1 421 Pfam PF01546 Peptidase family M20/M25/M40 88 399 3.6E-31 T 12-10-2018 IPR002933 Peptidase M20 GO:0016787 VAPA_1c11440 44456b5a18645230bb3507bc7e6a4ea1 421 PIRSF PIRSF005962 14 405 4.0E-115 T 12-10-2018 IPR017439 Amidohydrolase GO:0016787 VAPA_1c11440 44456b5a18645230bb3507bc7e6a4ea1 421 SUPERFAMILY SSF55031 199 313 3.93E-26 T 12-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain VAPA_1c11440 44456b5a18645230bb3507bc7e6a4ea1 421 Gene3D G3DSA:3.30.70.360 196 312 1.8E-126 T 12-10-2018 VAPA_1c11440 44456b5a18645230bb3507bc7e6a4ea1 421 Pfam PF07687 Peptidase dimerisation domain 201 297 1.5E-6 T 12-10-2018 IPR011650 Peptidase M20, dimerisation domain VAPA_1c11440 44456b5a18645230bb3507bc7e6a4ea1 421 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 26 390 5.9E-100 T 12-10-2018 IPR017439 Amidohydrolase GO:0016787 VAPA_1c13730 149ea11fe86f01960323f57d320a931c 965 Gene3D G3DSA:3.40.50.620 338 556 1.3E-74 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold VAPA_1c13730 149ea11fe86f01960323f57d320a931c 965 SUPERFAMILY SSF46589 900 964 1.15E-17 T 12-10-2018 IPR010978 Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm GO:0000166 VAPA_1c13730 149ea11fe86f01960323f57d320a931c 965 SUPERFAMILY SSF50677 217 368 3.53E-63 T 12-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 VAPA_1c13730 149ea11fe86f01960323f57d320a931c 965 Gene3D G3DSA:3.90.740.10 266 335 2.3E-9 T 12-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 VAPA_1c13730 149ea11fe86f01960323f57d320a931c 965 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 63 74 - T 12-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 VAPA_1c13730 149ea11fe86f01960323f57d320a931c 965 SUPERFAMILY SSF52374 17 642 6.28E-130 T 12-10-2018 VAPA_1c13730 149ea11fe86f01960323f57d320a931c 965 Pfam PF08264 Anticodon-binding domain of tRNA 688 835 1.9E-41 T 12-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 VAPA_1c13730 149ea11fe86f01960323f57d320a931c 965 PRINTS PR00986 Valyl-tRNA synthetase signature 507 525 1.5E-35 T 12-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 VAPA_1c13730 149ea11fe86f01960323f57d320a931c 965 PRINTS PR00986 Valyl-tRNA synthetase signature 56 67 1.5E-35 T 12-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 VAPA_1c13730 149ea11fe86f01960323f57d320a931c 965 PRINTS PR00986 Valyl-tRNA synthetase signature 256 273 1.5E-35 T 12-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 VAPA_1c13730 149ea11fe86f01960323f57d320a931c 965 PRINTS PR00986 Valyl-tRNA synthetase signature 476 497 1.5E-35 T 12-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 VAPA_1c13730 149ea11fe86f01960323f57d320a931c 965 PRINTS PR00986 Valyl-tRNA synthetase signature 372 385 1.5E-35 T 12-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 VAPA_1c13730 149ea11fe86f01960323f57d320a931c 965 Gene3D G3DSA:3.40.50.620 17 225 1.2E-58 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold VAPA_1c13730 149ea11fe86f01960323f57d320a931c 965 TIGRFAM TIGR00422 valS: valine--tRNA ligase 17 946 0.0 T 12-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 VAPA_1c13730 149ea11fe86f01960323f57d320a931c 965 SUPERFAMILY SSF47323 643 915 6.17E-63 T 12-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 VAPA_1c13730 149ea11fe86f01960323f57d320a931c 965 Gene3D G3DSA:1.10.730.10 593 831 1.1E-67 T 12-10-2018 VAPA_1c13730 149ea11fe86f01960323f57d320a931c 965 Gene3D G3DSA:3.90.740.10 226 265 3.2E-6 T 12-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 VAPA_1c13730 149ea11fe86f01960323f57d320a931c 965 Gene3D G3DSA:1.10.287.380 893 965 8.3E-17 T 12-10-2018 IPR037118 Valyl-tRNA synthetase, tRNA-binding arm superfamily GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: R-HSA-379716 VAPA_1c13730 149ea11fe86f01960323f57d320a931c 965 Hamap MF_02004 Valine--tRNA ligase [valS]. 16 965 15.408 T 12-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 VAPA_1c13730 149ea11fe86f01960323f57d320a931c 965 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 32 632 3.0E-201 T 12-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 VAPA_1c13730 149ea11fe86f01960323f57d320a931c 965 Pfam PF10458 Valyl tRNA synthetase tRNA binding arm 901 964 5.0E-20 T 12-10-2018 IPR019499 Valyl-tRNA synthetase, tRNA-binding arm GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9 VAPA_2c12260 7b2ab7c383a2a58c2cbc08c7c9d379ed 298 Gene3D G3DSA:3.40.190.10 168 266 1.1E-66 T 12-10-2018 VAPA_2c12260 7b2ab7c383a2a58c2cbc08c7c9d379ed 298 Gene3D G3DSA:3.40.190.10 90 289 1.1E-66 T 12-10-2018 VAPA_2c12260 7b2ab7c383a2a58c2cbc08c7c9d379ed 298 Gene3D G3DSA:1.10.10.10 1 86 2.0E-25 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_2c12260 7b2ab7c383a2a58c2cbc08c7c9d379ed 298 SUPERFAMILY SSF46785 2 83 2.01E-20 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_2c12260 7b2ab7c383a2a58c2cbc08c7c9d379ed 298 Pfam PF03466 LysR substrate binding domain 94 294 9.1E-32 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_2c12260 7b2ab7c383a2a58c2cbc08c7c9d379ed 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 21 32 4.1E-5 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_2c12260 7b2ab7c383a2a58c2cbc08c7c9d379ed 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 32 42 4.1E-5 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_2c12260 7b2ab7c383a2a58c2cbc08c7c9d379ed 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 53 4.1E-5 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_2c12260 7b2ab7c383a2a58c2cbc08c7c9d379ed 298 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 64 1.6E-15 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_2c12260 7b2ab7c383a2a58c2cbc08c7c9d379ed 298 SUPERFAMILY SSF53850 88 293 9.77E-49 T 12-10-2018 VAPA_1c07000 29a79932fbc47a2c3c7a1d1274854313 234 Gene3D G3DSA:3.90.850.10 2 233 1.0E-73 T 12-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 VAPA_1c07000 29a79932fbc47a2c3c7a1d1274854313 234 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 30 230 1.9E-48 T 12-10-2018 IPR011234 Fumarylacetoacetase-like, C-terminal GO:0003824 VAPA_1c07000 29a79932fbc47a2c3c7a1d1274854313 234 SUPERFAMILY SSF56529 18 233 1.7E-62 T 12-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 VAPA_1c15260 939afe4d31f61c846513f9fe084464ff 259 Hamap MF_00560 Trans-aconitate 2-methyltransferase [tam]. 2 258 43.084 T 12-10-2018 IPR023506 Trans-aconitate 2-methyltransferase GO:0030798 VAPA_1c15260 939afe4d31f61c846513f9fe084464ff 259 Pfam PF13489 Methyltransferase domain 13 142 1.4E-18 T 12-10-2018 VAPA_1c15260 939afe4d31f61c846513f9fe084464ff 259 Gene3D G3DSA:3.40.50.150 9 255 9.0E-88 T 12-10-2018 VAPA_1c15260 939afe4d31f61c846513f9fe084464ff 259 Gene3D G3DSA:1.10.150.290 133 238 9.0E-88 T 12-10-2018 IPR023149 Trans-aconitate 2-methyltransferase, C-terminal GO:0030798 VAPA_1c15260 939afe4d31f61c846513f9fe084464ff 259 SUPERFAMILY SSF53335 8 257 1.14E-37 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase VAPA_1c23090 b208f02c78a732f6070efed21bd28c40 398 SUPERFAMILY SSF53383 1 398 7.5E-123 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase VAPA_1c23090 b208f02c78a732f6070efed21bd28c40 398 Gene3D G3DSA:3.40.640.10 62 302 2.6E-163 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 VAPA_1c23090 b208f02c78a732f6070efed21bd28c40 398 Gene3D G3DSA:3.90.1150.10 7 394 2.6E-163 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 VAPA_1c23090 b208f02c78a732f6070efed21bd28c40 398 Pfam PF00155 Aminotransferase class I and II 29 394 6.7E-86 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 VAPA_1c23090 b208f02c78a732f6070efed21bd28c40 398 PRINTS PR00799 Aspartate aminotransferase signature 208 220 2.2E-37 T 12-10-2018 IPR000796 Aspartate/other aminotransferase GO:0006520|GO:0008483 KEGG: 00220+2.6.1.1|KEGG: 00250+2.6.1.1|KEGG: 00270+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 VAPA_1c23090 b208f02c78a732f6070efed21bd28c40 398 PRINTS PR00799 Aspartate aminotransferase signature 177 196 2.2E-37 T 12-10-2018 IPR000796 Aspartate/other aminotransferase GO:0006520|GO:0008483 KEGG: 00220+2.6.1.1|KEGG: 00250+2.6.1.1|KEGG: 00270+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 VAPA_1c23090 b208f02c78a732f6070efed21bd28c40 398 PRINTS PR00799 Aspartate aminotransferase signature 275 300 2.2E-37 T 12-10-2018 IPR000796 Aspartate/other aminotransferase GO:0006520|GO:0008483 KEGG: 00220+2.6.1.1|KEGG: 00250+2.6.1.1|KEGG: 00270+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 VAPA_1c23090 b208f02c78a732f6070efed21bd28c40 398 PRINTS PR00799 Aspartate aminotransferase signature 343 361 2.2E-37 T 12-10-2018 IPR000796 Aspartate/other aminotransferase GO:0006520|GO:0008483 KEGG: 00220+2.6.1.1|KEGG: 00250+2.6.1.1|KEGG: 00270+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 VAPA_1c23090 b208f02c78a732f6070efed21bd28c40 398 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 245 258 - T 12-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 VAPA_2c06250 1399b8e1f182b36d0039e4407339a3f5 586 TIGRFAM TIGR02516 type_III_yscC: type III secretion outer membrane pore, YscC/HrcC family 283 568 2.2E-83 T 12-10-2018 IPR003522 Type III secretion system outer membrane pore YscC/HrcC GO:0009306 VAPA_2c06250 1399b8e1f182b36d0039e4407339a3f5 586 Gene3D G3DSA:3.55.50.30 29 112 1.2E-20 T 12-10-2018 VAPA_2c06250 1399b8e1f182b36d0039e4407339a3f5 586 Pfam PF03958 Bacterial type II/III secretion system short domain 187 322 5.5E-17 T 12-10-2018 IPR005644 NolW-like VAPA_2c06250 1399b8e1f182b36d0039e4407339a3f5 586 Gene3D G3DSA:3.30.1370.120 113 183 1.2E-10 T 12-10-2018 IPR038591 NolW-like superfamily VAPA_2c06250 1399b8e1f182b36d0039e4407339a3f5 586 PRINTS PR01337 Type III secretion system outer membrane G protein family signature 424 443 1.3E-28 T 12-10-2018 IPR003522 Type III secretion system outer membrane pore YscC/HrcC GO:0009306 VAPA_2c06250 1399b8e1f182b36d0039e4407339a3f5 586 PRINTS PR01337 Type III secretion system outer membrane G protein family signature 458 473 1.3E-28 T 12-10-2018 IPR003522 Type III secretion system outer membrane pore YscC/HrcC GO:0009306 VAPA_2c06250 1399b8e1f182b36d0039e4407339a3f5 586 PRINTS PR01337 Type III secretion system outer membrane G protein family signature 198 215 1.3E-28 T 12-10-2018 IPR003522 Type III secretion system outer membrane pore YscC/HrcC GO:0009306 VAPA_2c06250 1399b8e1f182b36d0039e4407339a3f5 586 PRINTS PR01337 Type III secretion system outer membrane G protein family signature 547 566 1.3E-28 T 12-10-2018 IPR003522 Type III secretion system outer membrane pore YscC/HrcC GO:0009306 VAPA_2c06250 1399b8e1f182b36d0039e4407339a3f5 586 PRINTS PR01337 Type III secretion system outer membrane G protein family signature 325 345 1.3E-28 T 12-10-2018 IPR003522 Type III secretion system outer membrane pore YscC/HrcC GO:0009306 VAPA_2c06250 1399b8e1f182b36d0039e4407339a3f5 586 Pfam PF00263 Bacterial type II and III secretion system protein 411 568 1.4E-36 T 12-10-2018 IPR004846 Type II/III secretion system GO:0009306 VAPA_1c12940 42fe5b4286680e6b70f77b737cc3b85d 635 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 603 624 6.1E-12 T 12-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal VAPA_1c12940 42fe5b4286680e6b70f77b737cc3b85d 635 Gene3D G3DSA:3.40.50.300 376 625 1.0E-59 T 12-10-2018 VAPA_1c12940 42fe5b4286680e6b70f77b737cc3b85d 635 SMART SM00382 404 602 1.2E-6 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c12940 42fe5b4286680e6b70f77b737cc3b85d 635 SUPERFAMILY SSF52540 378 624 7.68E-63 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c12940 42fe5b4286680e6b70f77b737cc3b85d 635 Pfam PF02653 Branched-chain amino acid transport system / permease component 46 328 1.7E-34 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 VAPA_1c12940 42fe5b4286680e6b70f77b737cc3b85d 635 ProSitePatterns PS00211 ABC transporters family signature. 526 540 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_1c12940 42fe5b4286680e6b70f77b737cc3b85d 635 Pfam PF00005 ABC transporter 396 553 8.0E-28 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_2c02430 9b8539b8d8c85c8758e775e93324c61b 387 Gene3D G3DSA:3.30.1540.10 226 319 8.2E-113 T 12-10-2018 VAPA_2c02430 9b8539b8d8c85c8758e775e93324c61b 387 Pfam PF02515 CoA-transferase family III 5 368 1.1E-106 T 12-10-2018 IPR003673 CoA-transferase family III GO:0003824 VAPA_2c02430 9b8539b8d8c85c8758e775e93324c61b 387 SUPERFAMILY SSF89796 3 373 1.31E-112 T 12-10-2018 IPR023606 CoA-transferase family III domain superfamily VAPA_2c02430 9b8539b8d8c85c8758e775e93324c61b 387 Gene3D G3DSA:3.40.50.10540 5 372 8.2E-113 T 12-10-2018 IPR023606 CoA-transferase family III domain superfamily VAPA_2c10110 1c89b63df55ff97b50af8234adca98c0 328 SUPERFAMILY SSF53850 113 287 2.71E-11 T 12-10-2018 VAPA_2c10110 1c89b63df55ff97b50af8234adca98c0 328 PIRSF PIRSF017082 1 304 3.4E-60 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_2c10110 1c89b63df55ff97b50af8234adca98c0 328 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 49 298 5.0E-64 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_2c10110 1c89b63df55ff97b50af8234adca98c0 328 Gene3D G3DSA:3.40.190.10 128 250 9.1E-92 T 12-10-2018 VAPA_2c10110 1c89b63df55ff97b50af8234adca98c0 328 Gene3D G3DSA:3.40.190.150 30 311 9.1E-92 T 12-10-2018 VAPA_1c16630 4544c1fdf98b950ab95566491cd875b8 380 SUPERFAMILY SSF55961 173 379 4.0E-43 T 12-10-2018 VAPA_1c16630 4544c1fdf98b950ab95566491cd875b8 380 Gene3D G3DSA:2.102.10.10 35 159 6.6E-28 T 12-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 VAPA_1c16630 4544c1fdf98b950ab95566491cd875b8 380 Gene3D G3DSA:3.90.380.10 241 380 7.2E-11 T 12-10-2018 VAPA_1c16630 4544c1fdf98b950ab95566491cd875b8 380 Gene3D G3DSA:3.90.380.10 14 218 6.6E-28 T 12-10-2018 VAPA_1c16630 4544c1fdf98b950ab95566491cd875b8 380 Pfam PF00848 Ring hydroxylating alpha subunit (catalytic domain) 183 377 1.1E-31 T 12-10-2018 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0044237|GO:0051537|GO:0055114 VAPA_1c16630 4544c1fdf98b950ab95566491cd875b8 380 Pfam PF00355 Rieske [2Fe-2S] domain 47 128 3.8E-7 T 12-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 VAPA_1c16630 4544c1fdf98b950ab95566491cd875b8 380 SUPERFAMILY SSF50022 7 148 2.23E-27 T 12-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 VAPA_1c13190 befab014fae4c201e3b0abe48e265d67 343 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 67 339 2.5E-89 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c13190 befab014fae4c201e3b0abe48e265d67 343 Gene3D G3DSA:3.40.190.10 145 267 2.6E-110 T 12-10-2018 VAPA_1c13190 befab014fae4c201e3b0abe48e265d67 343 SUPERFAMILY SSF53850 134 306 2.26E-13 T 12-10-2018 VAPA_1c13190 befab014fae4c201e3b0abe48e265d67 343 PIRSF PIRSF017082 15 343 2.0E-79 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c13190 befab014fae4c201e3b0abe48e265d67 343 Gene3D G3DSA:3.40.190.150 47 333 2.6E-110 T 12-10-2018 VAPA_1c26190 a2d4f137a90221da2cf300f4a9ec6aa4 358 SUPERFAMILY SSF46689 301 351 2.42E-11 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 VAPA_1c26190 a2d4f137a90221da2cf300f4a9ec6aa4 358 Pfam PF12625 Arabinose-binding domain of AraC transcription regulator, N-term 39 222 2.5E-46 T 12-10-2018 IPR032687 HTH-type transcriptional regulator AraC-type, N-terminal VAPA_1c26190 a2d4f137a90221da2cf300f4a9ec6aa4 358 SMART SM00342 265 347 1.6E-22 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 VAPA_1c26190 a2d4f137a90221da2cf300f4a9ec6aa4 358 Pfam PF12833 Helix-turn-helix domain 272 349 8.6E-18 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 VAPA_1c26190 a2d4f137a90221da2cf300f4a9ec6aa4 358 Gene3D G3DSA:1.10.10.60 251 351 2.2E-21 T 12-10-2018 VAPA_2c05670 1f97a549325937a210e9fac8852606e3 252 Gene3D G3DSA:3.40.50.720 1 251 1.2E-73 T 12-10-2018 VAPA_2c05670 1f97a549325937a210e9fac8852606e3 252 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 247 2.6E-59 T 12-10-2018 VAPA_2c05670 1f97a549325937a210e9fac8852606e3 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 136 144 7.9E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c05670 1f97a549325937a210e9fac8852606e3 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 156 175 7.9E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c05670 1f97a549325937a210e9fac8852606e3 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 7.9E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c05670 1f97a549325937a210e9fac8852606e3 252 SUPERFAMILY SSF51735 1 248 2.29E-74 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_2c05670 1f97a549325937a210e9fac8852606e3 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 2.4E-40 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c05670 1f97a549325937a210e9fac8852606e3 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 2.4E-40 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c05670 1f97a549325937a210e9fac8852606e3 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 211 231 2.4E-40 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c05670 1f97a549325937a210e9fac8852606e3 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 2.4E-40 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c05670 1f97a549325937a210e9fac8852606e3 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 2.4E-40 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c05670 1f97a549325937a210e9fac8852606e3 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 2.4E-40 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c23680 97230a65fb4215490bc6e5e72b41b114 440 Pfam PF13393 Histidyl-tRNA synthetase 27 324 4.8E-41 T 12-10-2018 VAPA_1c23680 97230a65fb4215490bc6e5e72b41b114 440 Hamap MF_00127 Histidine--tRNA ligase [hisS]. 3 435 31.612 T 12-10-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 VAPA_1c23680 97230a65fb4215490bc6e5e72b41b114 440 SUPERFAMILY SSF52954 340 429 1.96E-18 T 12-10-2018 VAPA_1c23680 97230a65fb4215490bc6e5e72b41b114 440 PIRSF PIRSF001549 1 432 5.0E-109 T 12-10-2018 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 VAPA_1c23680 97230a65fb4215490bc6e5e72b41b114 440 Gene3D G3DSA:3.40.50.800 335 426 1.8E-20 T 12-10-2018 IPR036621 Anticodon-binding domain superfamily VAPA_1c23680 97230a65fb4215490bc6e5e72b41b114 440 Pfam PF03129 Anticodon binding domain 350 429 2.3E-10 T 12-10-2018 IPR004154 Anticodon-binding VAPA_1c23680 97230a65fb4215490bc6e5e72b41b114 440 TIGRFAM TIGR00442 hisS: histidine--tRNA ligase 7 419 6.1E-145 T 12-10-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 VAPA_1c23680 97230a65fb4215490bc6e5e72b41b114 440 Gene3D G3DSA:3.30.930.10 2 334 1.3E-113 T 12-10-2018 VAPA_1c23680 97230a65fb4215490bc6e5e72b41b114 440 SUPERFAMILY SSF55681 5 331 2.68E-96 T 12-10-2018 VAPA_1c20170 a90d1d41401fbc661ab67c4071af8071 222 SUPERFAMILY SSF51182 92 218 7.5E-19 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily VAPA_1c20170 a90d1d41401fbc661ab67c4071af8071 222 Pfam PF13560 Helix-turn-helix domain 40 97 5.8E-13 T 12-10-2018 VAPA_1c20170 a90d1d41401fbc661ab67c4071af8071 222 SUPERFAMILY SSF47413 36 103 5.91E-17 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 VAPA_1c20170 a90d1d41401fbc661ab67c4071af8071 222 Gene3D G3DSA:2.60.120.10 116 218 4.6E-16 T 12-10-2018 IPR014710 RmlC-like jelly roll fold VAPA_1c20170 a90d1d41401fbc661ab67c4071af8071 222 Pfam PF07883 Cupin domain 148 216 2.1E-9 T 12-10-2018 IPR013096 Cupin 2, conserved barrel VAPA_1c20170 a90d1d41401fbc661ab67c4071af8071 222 SMART SM00530 44 99 1.0E-13 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 VAPA_1c20170 a90d1d41401fbc661ab67c4071af8071 222 Gene3D G3DSA:1.10.260.40 35 109 2.0E-17 T 12-10-2018 VAPA_1c35980 2e29c85b223bea0a58caecb78f01241a 450 Pfam PF00529 HlyD membrane-fusion protein of T1SS 312 366 1.4E-8 T 12-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 VAPA_1c35980 2e29c85b223bea0a58caecb78f01241a 450 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 66 311 8.8E-15 T 12-10-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain VAPA_1c35980 2e29c85b223bea0a58caecb78f01241a 450 SUPERFAMILY SSF111369 67 193 4.05E-9 T 12-10-2018 VAPA_1c35980 2e29c85b223bea0a58caecb78f01241a 450 Gene3D G3DSA:2.40.50.100 68 101 7.4E-11 T 12-10-2018 VAPA_1c35980 2e29c85b223bea0a58caecb78f01241a 450 Gene3D G3DSA:1.10.287.470 102 123 7.4E-11 T 12-10-2018 VAPA_1c35980 2e29c85b223bea0a58caecb78f01241a 450 Gene3D G3DSA:1.10.287.470 128 210 5.6E-11 T 12-10-2018 VAPA_1c35980 2e29c85b223bea0a58caecb78f01241a 450 Gene3D G3DSA:2.40.30.170 253 374 8.1E-34 T 12-10-2018 VAPA_1c35980 2e29c85b223bea0a58caecb78f01241a 450 SUPERFAMILY SSF111369 208 290 4.05E-6 T 12-10-2018 VAPA_2c00530 7156b813a090d5d1666edb7f80765f70 109 Hamap MF_01663 L-rhamnose mutarotase [rhaM]. 1 104 28.714 T 12-10-2018 IPR013448 L-rhamnose mutarotase GO:0005737|GO:0016857|GO:0019299 VAPA_2c00530 7156b813a090d5d1666edb7f80765f70 109 Gene3D G3DSA:3.30.70.100 1 97 5.5E-35 T 12-10-2018 VAPA_2c00530 7156b813a090d5d1666edb7f80765f70 109 SUPERFAMILY SSF54909 4 103 1.12E-32 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel VAPA_2c00530 7156b813a090d5d1666edb7f80765f70 109 Pfam PF05336 L-rhamnose mutarotase 6 96 7.8E-25 T 12-10-2018 IPR008000 Rhamnose/fucose mutarotase GO:0005737|GO:0016857 VAPA_1c43020 dfbfeb091b292e6892be686457530a19 219 Gene3D G3DSA:3.40.250.10 108 219 2.4E-24 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily VAPA_1c43020 dfbfeb091b292e6892be686457530a19 219 SUPERFAMILY SSF46785 9 172 2.12E-19 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c43020 dfbfeb091b292e6892be686457530a19 219 Pfam PF00581 Rhodanese-like domain 125 210 5.6E-12 T 12-10-2018 IPR001763 Rhodanese-like domain VAPA_1c43020 dfbfeb091b292e6892be686457530a19 219 Gene3D G3DSA:1.10.10.10 1 102 3.5E-21 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c43020 dfbfeb091b292e6892be686457530a19 219 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 16 31 7.9E-8 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 VAPA_1c43020 dfbfeb091b292e6892be686457530a19 219 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 63 78 7.9E-8 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 VAPA_1c43020 dfbfeb091b292e6892be686457530a19 219 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 48 63 7.9E-8 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 VAPA_1c43020 dfbfeb091b292e6892be686457530a19 219 SMART SM00418 14 92 5.3E-19 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 VAPA_1c43020 dfbfeb091b292e6892be686457530a19 219 Pfam PF01022 Bacterial regulatory protein, arsR family 21 66 1.8E-8 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 VAPA_1c43020 dfbfeb091b292e6892be686457530a19 219 SMART SM00450 118 214 5.9E-15 T 12-10-2018 IPR001763 Rhodanese-like domain VAPA_1c43020 dfbfeb091b292e6892be686457530a19 219 SUPERFAMILY SSF52821 109 217 3.67E-26 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily VAPA_1c01870 4d34d936bbc09a806df8dc3e966acaf4 322 Pfam PF09084 NMT1/THI5 like 40 250 1.1E-20 T 12-10-2018 IPR015168 SsuA/THI5-like VAPA_1c01870 4d34d936bbc09a806df8dc3e966acaf4 322 Gene3D G3DSA:3.40.190.10 125 322 3.7E-24 T 12-10-2018 VAPA_1c01870 4d34d936bbc09a806df8dc3e966acaf4 322 Gene3D G3DSA:3.40.190.10 25 124 2.5E-11 T 12-10-2018 VAPA_1c01870 4d34d936bbc09a806df8dc3e966acaf4 322 SUPERFAMILY SSF53850 37 256 1.35E-35 T 12-10-2018 VAPA_1c50430 701468705408a40ed2864bfbf24ecf28 132 Gene3D G3DSA:3.10.450.50 6 132 2.0E-51 T 12-10-2018 VAPA_1c50430 701468705408a40ed2864bfbf24ecf28 132 Pfam PF11533 Protein of unknown function (DUF3225) 10 131 1.0E-60 T 12-10-2018 IPR024507 Protein of unknown function DUF3225 VAPA_1c50430 701468705408a40ed2864bfbf24ecf28 132 SUPERFAMILY SSF54427 8 131 4.26E-39 T 12-10-2018 IPR032710 NTF2-like domain superfamily VAPA_1c52960 0b8a3bd2200551f25c8440bdf679afae 550 Gene3D G3DSA:3.30.70.2450 212 297 1.5E-83 T 12-10-2018 VAPA_1c52960 0b8a3bd2200551f25c8440bdf679afae 550 Gene3D G3DSA:3.40.30.120 417 545 2.2E-5 T 12-10-2018 VAPA_1c52960 0b8a3bd2200551f25c8440bdf679afae 550 Pfam PF01494 FAD binding domain 32 370 9.1E-59 T 12-10-2018 IPR002938 FAD-binding domain GO:0071949 VAPA_1c52960 0b8a3bd2200551f25c8440bdf679afae 550 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 308 323 1.6E-35 T 12-10-2018 VAPA_1c52960 0b8a3bd2200551f25c8440bdf679afae 550 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 341 359 1.6E-35 T 12-10-2018 VAPA_1c52960 0b8a3bd2200551f25c8440bdf679afae 550 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 359 375 1.6E-35 T 12-10-2018 VAPA_1c52960 0b8a3bd2200551f25c8440bdf679afae 550 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 323 339 1.6E-35 T 12-10-2018 VAPA_1c52960 0b8a3bd2200551f25c8440bdf679afae 550 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 32 54 1.6E-35 T 12-10-2018 VAPA_1c52960 0b8a3bd2200551f25c8440bdf679afae 550 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 183 198 1.6E-35 T 12-10-2018 VAPA_1c52960 0b8a3bd2200551f25c8440bdf679afae 550 Gene3D G3DSA:3.50.50.60 33 369 1.5E-83 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c52960 0b8a3bd2200551f25c8440bdf679afae 550 SUPERFAMILY SSF51905 32 407 2.29E-60 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c33740 0ed9b03f78fcb49b06c5343a8e0865b0 323 Gene3D G3DSA:3.40.190.10 124 248 1.6E-110 T 12-10-2018 VAPA_1c33740 0ed9b03f78fcb49b06c5343a8e0865b0 323 Gene3D G3DSA:3.40.190.150 26 313 1.6E-110 T 12-10-2018 VAPA_1c33740 0ed9b03f78fcb49b06c5343a8e0865b0 323 PIRSF PIRSF017082 2 322 1.6E-82 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c33740 0ed9b03f78fcb49b06c5343a8e0865b0 323 SUPERFAMILY SSF53850 111 285 1.23E-12 T 12-10-2018 VAPA_1c33740 0ed9b03f78fcb49b06c5343a8e0865b0 323 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 45 318 1.3E-78 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_2c12560 c399007e76ee8760110ebb22b95b83df 378 Gene3D G3DSA:3.50.50.60 5 347 2.0E-79 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_2c12560 c399007e76ee8760110ebb22b95b83df 378 SUPERFAMILY SSF51905 4 362 4.32E-46 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_2c12560 c399007e76ee8760110ebb22b95b83df 378 SUPERFAMILY SSF54373 226 309 4.19E-12 T 12-10-2018 VAPA_2c12560 c399007e76ee8760110ebb22b95b83df 378 Pfam PF01266 FAD dependent oxidoreductase 5 337 1.3E-47 T 12-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 VAPA_2c12560 c399007e76ee8760110ebb22b95b83df 378 Gene3D G3DSA:3.30.9.10 91 308 2.0E-79 T 12-10-2018 VAPA_1c25220 e18b088495626b55659fa19adacb9608 393 Pfam PF01494 FAD binding domain 2 343 1.2E-91 T 12-10-2018 IPR002938 FAD-binding domain GO:0071949 VAPA_1c25220 e18b088495626b55659fa19adacb9608 393 TIGRFAM TIGR02360 pbenz_hydroxyl: 4-hydroxybenzoate 3-monooxygenase 1 390 2.4E-204 T 12-10-2018 IPR012733 4-hydroxybenzoate 3-monooxygenase GO:0018659|GO:0043639|GO:0050660|GO:0055114 VAPA_1c25220 e18b088495626b55659fa19adacb9608 393 SUPERFAMILY SSF51905 1 389 1.68E-55 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c25220 e18b088495626b55659fa19adacb9608 393 Gene3D G3DSA:3.30.9.10 73 387 1.3E-167 T 12-10-2018 VAPA_1c25220 e18b088495626b55659fa19adacb9608 393 Gene3D G3DSA:3.50.50.60 2 351 1.3E-167 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c25220 e18b088495626b55659fa19adacb9608 393 SUPERFAMILY SSF54373 175 275 3.69E-45 T 12-10-2018 VAPA_1c25220 e18b088495626b55659fa19adacb9608 393 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 278 293 9.5E-26 T 12-10-2018 VAPA_1c25220 e18b088495626b55659fa19adacb9608 393 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 4 26 9.5E-26 T 12-10-2018 VAPA_1c25220 e18b088495626b55659fa19adacb9608 393 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 293 309 9.5E-26 T 12-10-2018 VAPA_1c25220 e18b088495626b55659fa19adacb9608 393 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 151 166 9.5E-26 T 12-10-2018 VAPA_1c12380 adb85ad81f720a804a27b729808e4d19 119 PRINTS PR00332 Histidine triad family signature 29 47 2.6E-17 T 12-10-2018 IPR001310 Histidine triad (HIT) protein VAPA_1c12380 adb85ad81f720a804a27b729808e4d19 119 PRINTS PR00332 Histidine triad family signature 8 24 2.6E-17 T 12-10-2018 IPR001310 Histidine triad (HIT) protein VAPA_1c12380 adb85ad81f720a804a27b729808e4d19 119 PRINTS PR00332 Histidine triad family signature 100 110 2.6E-17 T 12-10-2018 IPR001310 Histidine triad (HIT) protein VAPA_1c12380 adb85ad81f720a804a27b729808e4d19 119 Gene3D G3DSA:3.30.428.10 1 117 5.6E-38 T 12-10-2018 IPR036265 HIT-like superfamily VAPA_1c12380 adb85ad81f720a804a27b729808e4d19 119 Pfam PF11969 Scavenger mRNA decapping enzyme C-term binding 6 111 1.1E-21 T 12-10-2018 VAPA_1c12380 adb85ad81f720a804a27b729808e4d19 119 ProSitePatterns PS00892 HIT domain signature. 93 111 - T 12-10-2018 IPR019808 Histidine triad, conserved site VAPA_1c12380 adb85ad81f720a804a27b729808e4d19 119 SUPERFAMILY SSF54197 1 114 5.41E-37 T 12-10-2018 IPR036265 HIT-like superfamily VAPA_1c13850 e2ccee317d5406d44712d8be1e115c07 387 SUPERFAMILY SSF47203 230 385 2.26E-43 T 12-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 VAPA_1c13850 e2ccee317d5406d44712d8be1e115c07 387 Gene3D G3DSA:2.40.110.10 121 236 1.3E-34 T 12-10-2018 VAPA_1c13850 e2ccee317d5406d44712d8be1e115c07 387 Gene3D G3DSA:1.20.140.10 237 380 7.7E-36 T 12-10-2018 VAPA_1c13850 e2ccee317d5406d44712d8be1e115c07 387 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 121 219 5.9E-21 T 12-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 VAPA_1c13850 e2ccee317d5406d44712d8be1e115c07 387 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 232 370 3.3E-32 T 12-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 VAPA_1c13850 e2ccee317d5406d44712d8be1e115c07 387 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 12 116 4.4E-24 T 12-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 VAPA_1c13850 e2ccee317d5406d44712d8be1e115c07 387 PIRSF PIRSF016578 237 386 9.3E-6 T 12-10-2018 VAPA_1c13850 e2ccee317d5406d44712d8be1e115c07 387 PIRSF PIRSF016578 3 195 6.4E-8 T 12-10-2018 VAPA_1c13850 e2ccee317d5406d44712d8be1e115c07 387 Gene3D G3DSA:1.10.540.10 8 116 7.3E-29 T 12-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 VAPA_1c13850 e2ccee317d5406d44712d8be1e115c07 387 SUPERFAMILY SSF56645 9 244 9.03E-62 T 12-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 VAPA_1c13850 e2ccee317d5406d44712d8be1e115c07 387 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 339 358 - T 12-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 VAPA_1c26740 8da5b76a3a7d98daf9ca812451694420 403 SUPERFAMILY SSF51604 98 386 3.14E-76 T 12-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily VAPA_1c26740 8da5b76a3a7d98daf9ca812451694420 403 SUPERFAMILY SSF54826 1 112 7.22E-34 T 12-10-2018 VAPA_1c26740 8da5b76a3a7d98daf9ca812451694420 403 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 16 110 1.2E-31 T 12-10-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain VAPA_1c26740 8da5b76a3a7d98daf9ca812451694420 403 SMART SM00922 128 257 2.2E-17 T 12-10-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal VAPA_1c26740 8da5b76a3a7d98daf9ca812451694420 403 ProSitePatterns PS00908 Mandelate racemase / muconate lactonizing enzyme family signature 1. 85 110 - T 12-10-2018 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 VAPA_1c26740 8da5b76a3a7d98daf9ca812451694420 403 Gene3D G3DSA:3.30.390.10 5 399 6.6E-172 T 12-10-2018 IPR029017 Enolase-like, N-terminal VAPA_1c26740 8da5b76a3a7d98daf9ca812451694420 403 Gene3D G3DSA:3.20.20.120 105 366 6.6E-172 T 12-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily VAPA_1c26740 8da5b76a3a7d98daf9ca812451694420 403 Pfam PF13378 Enolase C-terminal domain-like 135 377 1.0E-39 T 12-10-2018 IPR029065 Enolase C-terminal domain-like VAPA_1c05690 0a3cf9599cb4af0adf2706461130a784 209 Gene3D G3DSA:3.40.50.850 5 209 2.3E-55 T 12-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 VAPA_1c05690 0a3cf9599cb4af0adf2706461130a784 209 Pfam PF00857 Isochorismatase family 10 161 2.2E-33 T 12-10-2018 IPR000868 Isochorismatase-like GO:0003824 VAPA_1c05690 0a3cf9599cb4af0adf2706461130a784 209 SUPERFAMILY SSF52499 6 191 1.96E-46 T 12-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 VAPA_1c34840 a24d3c9ea81d46991f9ffa27e122c5c3 377 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 283 360 1.8E-12 T 12-10-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 VAPA_1c34840 a24d3c9ea81d46991f9ffa27e122c5c3 377 SUPERFAMILY SSF53901 47 369 2.03E-27 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 VAPA_1c34840 a24d3c9ea81d46991f9ffa27e122c5c3 377 Gene3D G3DSA:3.40.47.10 224 377 8.8E-32 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 VAPA_1c34840 a24d3c9ea81d46991f9ffa27e122c5c3 377 Gene3D G3DSA:3.40.47.10 5 203 3.6E-33 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 VAPA_1c34840 a24d3c9ea81d46991f9ffa27e122c5c3 377 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 120 201 9.7E-5 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal VAPA_1c33970 97afa075ccf7ffe7a3ef82764518c36b 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 85 96 1.0E-12 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c33970 97afa075ccf7ffe7a3ef82764518c36b 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 147 155 1.0E-12 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c33970 97afa075ccf7ffe7a3ef82764518c36b 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 167 186 1.0E-12 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c33970 97afa075ccf7ffe7a3ef82764518c36b 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 141 157 5.0E-37 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c33970 97afa075ccf7ffe7a3ef82764518c36b 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 222 242 5.0E-37 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c33970 97afa075ccf7ffe7a3ef82764518c36b 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 188 205 5.0E-37 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c33970 97afa075ccf7ffe7a3ef82764518c36b 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 167 186 5.0E-37 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c33970 97afa075ccf7ffe7a3ef82764518c36b 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 11 28 5.0E-37 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c33970 97afa075ccf7ffe7a3ef82764518c36b 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 85 96 5.0E-37 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c33970 97afa075ccf7ffe7a3ef82764518c36b 260 SUPERFAMILY SSF51735 5 259 2.09E-77 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c33970 97afa075ccf7ffe7a3ef82764518c36b 260 Gene3D G3DSA:3.40.50.720 1 260 9.9E-83 T 12-10-2018 VAPA_1c33970 97afa075ccf7ffe7a3ef82764518c36b 260 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 154 182 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 VAPA_1c33970 97afa075ccf7ffe7a3ef82764518c36b 260 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 258 1.7E-56 T 12-10-2018 VAPA_1c33970 97afa075ccf7ffe7a3ef82764518c36b 260 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 10 212 0.0025 T 12-10-2018 VAPA_2c02830 cc99ae1d7db2e5a8d9b4ed007911a564 311 Pfam PF05681 Fumarate hydratase (Fumerase) 10 283 1.3E-66 T 12-10-2018 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 VAPA_2c02830 cc99ae1d7db2e5a8d9b4ed007911a564 311 TIGRFAM TIGR00722 ttdA_fumA_fumB: hydrolyase, tartrate alpha subunit/fumarate domain protein, Fe-S type 8 285 2.6E-66 T 12-10-2018 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 VAPA_2c12660 ba28998ab78e8a6f40bed80a46f00c0e 133 SUPERFAMILY SSF54534 46 122 3.14E-16 T 12-10-2018 VAPA_2c12660 ba28998ab78e8a6f40bed80a46f00c0e 133 PIRSF PIRSF006092 9 125 1.5E-20 T 12-10-2018 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 VAPA_2c12660 ba28998ab78e8a6f40bed80a46f00c0e 133 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 48 121 6.5E-20 T 12-10-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 VAPA_2c12660 ba28998ab78e8a6f40bed80a46f00c0e 133 ProSitePatterns PS00830 Prokaryotic transcription elongation factors signature 2. 86 102 - T 12-10-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 VAPA_2c12660 ba28998ab78e8a6f40bed80a46f00c0e 133 Gene3D G3DSA:3.10.50.30 42 133 5.4E-27 T 12-10-2018 IPR036953 Transcription elongation factor GreA/GreB, C-terminal domain superfamily GO:0003677|GO:0032784 VAPA_1c49030 e02a1c9d56a1d61014c465f683ddd6e8 225 SUPERFAMILY SSF46689 26 94 2.15E-13 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 VAPA_1c49030 e02a1c9d56a1d61014c465f683ddd6e8 225 Pfam PF00440 Bacterial regulatory proteins, tetR family 37 83 4.6E-11 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 VAPA_1c49030 e02a1c9d56a1d61014c465f683ddd6e8 225 Gene3D G3DSA:1.10.10.60 18 82 3.6E-14 T 12-10-2018 VAPA_1c49030 e02a1c9d56a1d61014c465f683ddd6e8 225 Gene3D G3DSA:1.10.357.10 84 223 1.1E-38 T 12-10-2018 VAPA_1c49030 e02a1c9d56a1d61014c465f683ddd6e8 225 SUPERFAMILY SSF48498 101 223 8.9E-32 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily VAPA_1c49030 e02a1c9d56a1d61014c465f683ddd6e8 225 Pfam PF08362 YcdC-like protein, C-terminal region 85 222 2.6E-31 T 12-10-2018 IPR013573 Transcription regulator YcdC, C-terminal GO:0045892 VAPA_1c34870 135c99a919a711e6bed003d94cb5f41d 102 Pfam PF09928 Predicted small integral membrane protein (DUF2160) 4 102 2.6E-37 T 12-10-2018 IPR018678 Protein of unknown function DUF2160, transmembrane VAPA_1c46150 ba6b59a41baa13e1b3cf5ccaa4d03f96 398 Gene3D G3DSA:1.25.40.10 39 180 4.9E-26 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 VAPA_1c46150 ba6b59a41baa13e1b3cf5ccaa4d03f96 398 SMART SM00028 71 104 84.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 VAPA_1c46150 ba6b59a41baa13e1b3cf5ccaa4d03f96 398 SMART SM00028 139 167 78.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 VAPA_1c46150 ba6b59a41baa13e1b3cf5ccaa4d03f96 398 SMART SM00028 105 138 3.4E-4 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 VAPA_1c46150 ba6b59a41baa13e1b3cf5ccaa4d03f96 398 Pfam PF13414 TPR repeat 114 152 8.1E-7 T 12-10-2018 VAPA_1c46150 ba6b59a41baa13e1b3cf5ccaa4d03f96 398 Gene3D G3DSA:3.10.450.50 283 397 3.9E-9 T 12-10-2018 VAPA_1c46150 ba6b59a41baa13e1b3cf5ccaa4d03f96 398 SUPERFAMILY SSF48452 46 177 6.12E-23 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 VAPA_1c46150 ba6b59a41baa13e1b3cf5ccaa4d03f96 398 Pfam PF13432 Tetratricopeptide repeat 43 101 5.5E-8 T 12-10-2018 VAPA_1c46150 ba6b59a41baa13e1b3cf5ccaa4d03f96 398 SUPERFAMILY SSF54427 287 391 4.79E-14 T 12-10-2018 IPR032710 NTF2-like domain superfamily VAPA_1c50290 5b3403faa773b2e94a8a728e33772acb 302 Gene3D G3DSA:3.10.310.50 27 176 2.4E-43 T 12-10-2018 VAPA_1c50290 5b3403faa773b2e94a8a728e33772acb 302 Pfam PF04536 TPM domain 42 164 1.0E-34 T 12-10-2018 IPR007621 TPM domain VAPA_1c05840 0da1c1baefb1371183b935f0411847c7 574 Pfam PF03865 Haemolysin secretion/activation protein ShlB/FhaC/HecB 219 532 6.9E-24 T 12-10-2018 IPR005565 Haemolysin activator HlyB, C-terminal VAPA_1c05840 0da1c1baefb1371183b935f0411847c7 574 Pfam PF08479 POTRA domain, ShlB-type 80 155 2.0E-19 T 12-10-2018 IPR013686 Polypeptide-transport-associated, ShlB-type VAPA_1c05840 0da1c1baefb1371183b935f0411847c7 574 Gene3D G3DSA:3.10.20.310 74 155 1.4E-19 T 12-10-2018 VAPA_1c05840 0da1c1baefb1371183b935f0411847c7 574 Gene3D G3DSA:2.40.160.50 191 569 4.5E-84 T 12-10-2018 VAPA_2c12980 84f01e2dd169e2590b39fb3d8d8d1d3d 261 Gene3D G3DSA:3.40.190.10 119 215 5.7E-71 T 12-10-2018 VAPA_2c12980 84f01e2dd169e2590b39fb3d8d8d1d3d 261 SMART SM00062 33 259 3.4E-57 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF VAPA_2c12980 84f01e2dd169e2590b39fb3d8d8d1d3d 261 SUPERFAMILY SSF53850 18 258 8.83E-62 T 12-10-2018 VAPA_2c12980 84f01e2dd169e2590b39fb3d8d8d1d3d 261 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 35 256 6.5E-60 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF VAPA_2c12980 84f01e2dd169e2590b39fb3d8d8d1d3d 261 Gene3D G3DSA:3.40.190.10 36 256 5.7E-71 T 12-10-2018 VAPA_1c05150 b42137b8a40a28eca59d06d7e291abdc 255 Gene3D G3DSA:3.60.20.10 1 254 1.3E-99 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal VAPA_1c05150 b42137b8a40a28eca59d06d7e291abdc 255 SUPERFAMILY SSF56235 2 251 1.45E-48 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal VAPA_1c05150 b42137b8a40a28eca59d06d7e291abdc 255 Pfam PF13230 Glutamine amidotransferases class-II 1 252 7.1E-124 T 12-10-2018 IPR026869 Putative glutamine amidotransferase type 2 VAPA_1c02500 1aa21739b26bc4750c6c6ac8f0d4b73e 241 TIGRFAM TIGR03373 VI_minor_4: type VI secretion-associated protein, BMA_A0400 family 19 149 2.7E-35 T 12-10-2018 IPR017748 T6S-associated protein TagF VAPA_1c02500 1aa21739b26bc4750c6c6ac8f0d4b73e 241 Pfam PF09867 Uncharacterized protein conserved in bacteria (DUF2094) 19 150 2.4E-41 T 12-10-2018 IPR017748 T6S-associated protein TagF VAPA_1c02500 1aa21739b26bc4750c6c6ac8f0d4b73e 241 Gene3D G3DSA:3.40.1730.10 15 239 3.4E-44 T 12-10-2018 IPR038225 T6S-associated protein TagF superfamily VAPA_1c02500 1aa21739b26bc4750c6c6ac8f0d4b73e 241 PIRSF PIRSF029287 12 239 2.1E-51 T 12-10-2018 IPR017748 T6S-associated protein TagF VAPA_1c41930 e1a5618a290678ed7a314753233ef0b3 342 Gene3D G3DSA:1.10.287.90 24 110 2.1E-31 T 12-10-2018 IPR036257 Cytochrome C oxidase subunit II, transmembrane domain superfamily Reactome: R-HSA-5628897|Reactome: R-HSA-611105 VAPA_1c41930 e1a5618a290678ed7a314753233ef0b3 342 Pfam PF00116 Cytochrome C oxidase subunit II, periplasmic domain 155 225 1.1E-6 T 12-10-2018 IPR002429 Cytochrome c oxidase subunit II-like C-terminal GO:0004129|GO:0005507|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 VAPA_1c41930 e1a5618a290678ed7a314753233ef0b3 342 Pfam PF06481 COX Aromatic Rich Motif 249 288 1.2E-14 T 12-10-2018 IPR010514 COX aromatic rich motif GO:0008827|GO:0016021|GO:0022900|GO:0055114 VAPA_1c41930 e1a5618a290678ed7a314753233ef0b3 342 SUPERFAMILY SSF81464 16 114 1.13E-21 T 12-10-2018 IPR036257 Cytochrome C oxidase subunit II, transmembrane domain superfamily Reactome: R-HSA-5628897|Reactome: R-HSA-611105 VAPA_1c41930 e1a5618a290678ed7a314753233ef0b3 342 Gene3D G3DSA:2.60.40.420 117 287 2.1E-53 T 12-10-2018 IPR008972 Cupredoxin VAPA_1c41930 e1a5618a290678ed7a314753233ef0b3 342 SUPERFAMILY SSF49503 127 285 3.84E-51 T 12-10-2018 IPR008972 Cupredoxin VAPA_1c41930 e1a5618a290678ed7a314753233ef0b3 342 TIGRFAM TIGR01433 CyoA: ubiquinol oxidase, subunit II 15 244 2.7E-106 T 12-10-2018 IPR006333 Cytochrome o ubiquinol oxidase subunit II GO:0016020|GO:0016682|GO:0055114 VAPA_1c41930 e1a5618a290678ed7a314753233ef0b3 342 PIRSF PIRSF000292 1 315 3.6E-126 T 12-10-2018 IPR006333 Cytochrome o ubiquinol oxidase subunit II GO:0016020|GO:0016682|GO:0055114 VAPA_1c20220 c1b7bd9be87560f4c1251a554ec0adbd 323 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 29 85 2.9E-7 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 VAPA_1c20220 c1b7bd9be87560f4c1251a554ec0adbd 323 Pfam PF00107 Zinc-binding dehydrogenase 151 255 6.9E-26 T 12-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 VAPA_1c20220 c1b7bd9be87560f4c1251a554ec0adbd 323 Gene3D G3DSA:3.90.180.10 12 317 1.7E-105 T 12-10-2018 VAPA_1c20220 c1b7bd9be87560f4c1251a554ec0adbd 323 Gene3D G3DSA:3.40.50.720 123 267 1.7E-105 T 12-10-2018 VAPA_1c20220 c1b7bd9be87560f4c1251a554ec0adbd 323 SMART SM00829 11 321 1.3E-29 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 VAPA_1c20220 c1b7bd9be87560f4c1251a554ec0adbd 323 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 140 161 - T 12-10-2018 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 VAPA_1c20220 c1b7bd9be87560f4c1251a554ec0adbd 323 SUPERFAMILY SSF50129 2 144 1.83E-36 T 12-10-2018 IPR011032 GroES-like superfamily VAPA_1c20220 c1b7bd9be87560f4c1251a554ec0adbd 323 SUPERFAMILY SSF51735 111 274 1.56E-43 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c08350 4e282a8e95b43f65dfcd66a624916a5c 297 Gene3D G3DSA:3.40.1160.10 10 296 2.6E-97 T 12-10-2018 IPR036393 Acetylglutamate kinase-like superfamily VAPA_1c08350 4e282a8e95b43f65dfcd66a624916a5c 297 SUPERFAMILY SSF53633 10 295 4.06E-90 T 12-10-2018 IPR036393 Acetylglutamate kinase-like superfamily VAPA_1c08350 4e282a8e95b43f65dfcd66a624916a5c 297 PRINTS PR00474 Glutamate 5-kinase family signature 246 266 5.9E-6 T 12-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 VAPA_1c08350 4e282a8e95b43f65dfcd66a624916a5c 297 PRINTS PR00474 Glutamate 5-kinase family signature 196 223 5.9E-6 T 12-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 VAPA_1c08350 4e282a8e95b43f65dfcd66a624916a5c 297 Hamap MF_00082 Acetylglutamate kinase [argB]. 29 289 49.192 T 12-10-2018 IPR037528 Acetylglutamate kinase ArgB GO:0003991|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 VAPA_1c08350 4e282a8e95b43f65dfcd66a624916a5c 297 TIGRFAM TIGR00761 argB: acetylglutamate kinase 31 271 6.9E-73 T 12-10-2018 IPR004662 Acetylglutamate kinase family GO:0005737 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 VAPA_1c08350 4e282a8e95b43f65dfcd66a624916a5c 297 Pfam PF00696 Amino acid kinase family 30 273 1.2E-46 T 12-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 VAPA_1c08350 4e282a8e95b43f65dfcd66a624916a5c 297 PIRSF PIRSF000728 15 296 4.9E-101 T 12-10-2018 IPR004662 Acetylglutamate kinase family GO:0005737 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 VAPA_1c48340 d8ef4075849ece720d2f96098639ddf2 263 Gene3D G3DSA:3.40.50.150 67 261 1.6E-71 T 12-10-2018 VAPA_1c48340 d8ef4075849ece720d2f96098639ddf2 263 Gene3D G3DSA:3.10.290.10 1 66 9.8E-12 T 12-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 VAPA_1c48340 d8ef4075849ece720d2f96098639ddf2 263 PIRSF PIRSF005578 1 262 9.8E-98 T 12-10-2018 IPR004538 Haemolysin A /rRNA methyltransferase TlyA GO:0003723 VAPA_1c48340 d8ef4075849ece720d2f96098639ddf2 263 Pfam PF01728 FtsJ-like methyltransferase 64 253 1.8E-20 T 12-10-2018 IPR002877 Ribosomal RNA methyltransferase FtsJ domain GO:0008168|GO:0032259 VAPA_1c48340 d8ef4075849ece720d2f96098639ddf2 263 SUPERFAMILY SSF53335 64 256 9.02E-22 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase VAPA_2c09340 2e2f192f79c7a382df33cc7bf2f35b4a 363 Gene3D G3DSA:3.20.20.70 1 361 4.1E-124 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 VAPA_2c09340 2e2f192f79c7a382df33cc7bf2f35b4a 363 SUPERFAMILY SSF51395 1 359 9.77E-110 T 12-10-2018 VAPA_2c09340 2e2f192f79c7a382df33cc7bf2f35b4a 363 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 4 334 7.9E-75 T 12-10-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 VAPA_2c00600 a03acb201aa2f1b65f05308b8a8d525f 265 ProSitePatterns PS00211 ABC transporters family signature. 155 169 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_2c00600 a03acb201aa2f1b65f05308b8a8d525f 265 Pfam PF00005 ABC transporter 24 183 5.6E-28 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_2c00600 a03acb201aa2f1b65f05308b8a8d525f 265 SMART SM00382 33 262 5.1E-9 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_2c00600 a03acb201aa2f1b65f05308b8a8d525f 265 SUPERFAMILY SSF52540 8 253 2.51E-63 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_2c00600 a03acb201aa2f1b65f05308b8a8d525f 265 Gene3D G3DSA:3.40.50.300 4 254 7.9E-65 T 12-10-2018 VAPA_1c01970 bf3fd9f3f9e7097049c5bf215b78ca2a 250 SMART SM00079 30 247 1.3E-4 T 12-10-2018 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 VAPA_1c01970 bf3fd9f3f9e7097049c5bf215b78ca2a 250 SMART SM00062 30 248 4.8E-69 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF VAPA_1c01970 bf3fd9f3f9e7097049c5bf215b78ca2a 250 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 52 65 - T 12-10-2018 IPR018313 Solute-binding protein family 3, conserved site VAPA_1c01970 bf3fd9f3f9e7097049c5bf215b78ca2a 250 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 31 246 4.8E-67 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF VAPA_1c01970 bf3fd9f3f9e7097049c5bf215b78ca2a 250 Gene3D G3DSA:3.40.190.10 33 245 1.6E-72 T 12-10-2018 VAPA_1c01970 bf3fd9f3f9e7097049c5bf215b78ca2a 250 SUPERFAMILY SSF53850 7 246 1.19E-70 T 12-10-2018 VAPA_1c01970 bf3fd9f3f9e7097049c5bf215b78ca2a 250 Gene3D G3DSA:3.40.190.10 114 207 1.6E-72 T 12-10-2018 VAPA_1c05440 872d68bebf880c4d07ecc88a8095cb39 239 Gene3D G3DSA:2.60.450.10 37 196 3.2E-41 T 12-10-2018 VAPA_1c05440 872d68bebf880c4d07ecc88a8095cb39 239 TIGRFAM TIGR03002 outer_YhbN_LptA: lipopolysaccharide transport periplasmic protein LptA 35 193 4.1E-32 T 12-10-2018 IPR014340 Lipopolysaccharide export system protein LptA GO:0001530|GO:0015920|GO:0042597 VAPA_1c05440 872d68bebf880c4d07ecc88a8095cb39 239 Pfam PF03968 OstA-like protein 45 162 6.4E-21 T 12-10-2018 IPR005653 Organic solvent tolerance-like, N-terminal VAPA_1c05440 872d68bebf880c4d07ecc88a8095cb39 239 Hamap MF_01914 Lipopolysaccharide export system protein LptA [lptA]. 18 193 24.447 T 12-10-2018 IPR014340 Lipopolysaccharide export system protein LptA GO:0001530|GO:0015920|GO:0042597 VAPA_1c12820 bf90a7f70303b0cb89e7b85d38fcca5e 58 Pfam PF00171 Aldehyde dehydrogenase family 14 46 4.8E-7 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 VAPA_1c12820 bf90a7f70303b0cb89e7b85d38fcca5e 58 SUPERFAMILY SSF53720 12 54 8.55E-10 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 VAPA_1c12820 bf90a7f70303b0cb89e7b85d38fcca5e 58 Gene3D G3DSA:3.40.309.10 5 58 1.4E-8 T 12-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 VAPA_2c01500 0c6d6b66e39961a12d9d11297ee38665 331 Gene3D G3DSA:3.40.190.150 32 321 4.7E-110 T 12-10-2018 VAPA_2c01500 0c6d6b66e39961a12d9d11297ee38665 331 Gene3D G3DSA:3.40.190.10 130 256 4.7E-110 T 12-10-2018 VAPA_2c01500 0c6d6b66e39961a12d9d11297ee38665 331 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 52 327 1.5E-80 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_2c01500 0c6d6b66e39961a12d9d11297ee38665 331 PIRSF PIRSF017082 1 330 3.7E-74 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_2c01500 0c6d6b66e39961a12d9d11297ee38665 331 SUPERFAMILY SSF53850 119 288 1.21E-13 T 12-10-2018 VAPA_2c00230 80234bd9312cfb5f076cc4afea7d8145 381 Gene3D G3DSA:3.40.50.2300 124 355 7.8E-138 T 12-10-2018 VAPA_2c00230 80234bd9312cfb5f076cc4afea7d8145 381 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 238 256 1.1E-5 T 12-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 VAPA_2c00230 80234bd9312cfb5f076cc4afea7d8145 381 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 50 68 1.1E-5 T 12-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 VAPA_2c00230 80234bd9312cfb5f076cc4afea7d8145 381 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 31 47 1.1E-5 T 12-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 VAPA_2c00230 80234bd9312cfb5f076cc4afea7d8145 381 Pfam PF13433 Periplasmic binding protein domain 9 369 2.5E-139 T 12-10-2018 VAPA_2c00230 80234bd9312cfb5f076cc4afea7d8145 381 SUPERFAMILY SSF53822 9 369 1.08E-94 T 12-10-2018 IPR028082 Periplasmic binding protein-like I VAPA_2c00230 80234bd9312cfb5f076cc4afea7d8145 381 Gene3D G3DSA:3.40.50.2300 11 339 7.8E-138 T 12-10-2018 VAPA_2c02040 4a18b3ba6f71d7a5fc77ff3b5131d087 168 SUPERFAMILY SSF49503 51 160 4.03E-33 T 12-10-2018 IPR008972 Cupredoxin VAPA_2c02040 4a18b3ba6f71d7a5fc77ff3b5131d087 168 ProDom PD003655 COPPER ELECTRON AZURIN METAL-BINDING PERIPLASMIC PRECURSOR SIGNAL SEQUENCING DIRECT MEMBRANE 60 156 2.0E-4 T 12-10-2018 VAPA_2c02040 4a18b3ba6f71d7a5fc77ff3b5131d087 168 ProSitePatterns PS00079 Multicopper oxidases signature 1. 138 158 - T 12-10-2018 IPR033138 Multicopper oxidases, conserved site VAPA_2c02040 4a18b3ba6f71d7a5fc77ff3b5131d087 168 Pfam PF00127 Copper binding proteins, plastocyanin/azurin family 54 160 7.2E-13 T 12-10-2018 IPR000923 Blue (type 1) copper domain GO:0005507|GO:0009055 VAPA_2c02040 4a18b3ba6f71d7a5fc77ff3b5131d087 168 Gene3D G3DSA:2.60.40.420 36 161 4.3E-32 T 12-10-2018 IPR008972 Cupredoxin VAPA_1c54860 191cd5c27bdcb687da61bda63206a364 885 Hamap MF_01411 LPS-assembly protein LptD [lptD]. 43 852 17.774 T 12-10-2018 IPR020889 LPS-assembly protein LptD GO:0009279|GO:0010033|GO:0015920|GO:0043165 VAPA_1c54860 191cd5c27bdcb687da61bda63206a364 885 Pfam PF04453 Organic solvent tolerance protein 363 774 2.4E-77 T 12-10-2018 IPR007543 Organic solvent tolerance protein, C-terminal GO:0010033|GO:0019867|GO:0061024 VAPA_1c35320 470d89743568c957c5e157f32451e393 800 Gene3D G3DSA:3.30.1360.40 253 369 4.1E-178 T 12-10-2018 VAPA_1c35320 470d89743568c957c5e157f32451e393 800 Hamap MF_00936 DNA topoisomerase 4 subunit A [parC]. 12 798 31.496 T 12-10-2018 IPR005742 DNA topoisomerase IV, subunit A, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 VAPA_1c35320 470d89743568c957c5e157f32451e393 800 Gene3D G3DSA:3.90.199.10 40 521 4.1E-178 T 12-10-2018 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 VAPA_1c35320 470d89743568c957c5e157f32451e393 800 Gene3D G3DSA:1.10.268.10 407 492 4.1E-178 T 12-10-2018 IPR013757 Type IIA DNA topoisomerase subunit A, alpha-helical domain superfamily GO:0003677|GO:0003918|GO:0005524 Reactome: R-HSA-4615885 VAPA_1c35320 470d89743568c957c5e157f32451e393 800 Gene3D G3DSA:2.120.10.90 534 785 6.9E-16 T 12-10-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal VAPA_1c35320 470d89743568c957c5e157f32451e393 800 SUPERFAMILY SSF56719 39 521 3.79E-136 T 12-10-2018 IPR013760 DNA topoisomerase, type IIA-like domain superfamily GO:0003918|GO:0005524 Reactome: R-HSA-4615885 VAPA_1c35320 470d89743568c957c5e157f32451e393 800 SMART SM00434 19 499 3.4E-203 T 12-10-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 VAPA_1c35320 470d89743568c957c5e157f32451e393 800 SUPERFAMILY SSF101904 533 787 4.71E-35 T 12-10-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal VAPA_1c35320 470d89743568c957c5e157f32451e393 800 TIGRFAM TIGR01062 parC_Gneg: DNA topoisomerase IV, A subunit 19 792 3.5E-205 T 12-10-2018 VAPA_1c35320 470d89743568c957c5e157f32451e393 800 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 40 502 5.5E-121 T 12-10-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 VAPA_1c06980 8679f937ebba7f5a49569ba434377bf5 431 Pfam PF01590 GAF domain 88 210 1.1E-5 T 12-10-2018 IPR003018 GAF domain GO:0005515 VAPA_1c06980 8679f937ebba7f5a49569ba434377bf5 431 Gene3D G3DSA:3.30.450.40 31 214 1.0E-41 T 12-10-2018 IPR029016 GAF-like domain superfamily VAPA_1c06980 8679f937ebba7f5a49569ba434377bf5 431 SUPERFAMILY SSF46689 390 424 6.27E-8 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 VAPA_1c06980 8679f937ebba7f5a49569ba434377bf5 431 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 392 409 1.7E-6 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 VAPA_1c06980 8679f937ebba7f5a49569ba434377bf5 431 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 409 429 1.7E-6 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 VAPA_1c06980 8679f937ebba7f5a49569ba434377bf5 431 Gene3D G3DSA:1.10.10.60 372 426 1.6E-8 T 12-10-2018 VAPA_1c06980 8679f937ebba7f5a49569ba434377bf5 431 SUPERFAMILY SSF55781 87 215 9.81E-8 T 12-10-2018 VAPA_1c06980 8679f937ebba7f5a49569ba434377bf5 431 Pfam PF02954 Bacterial regulatory protein, Fis family 392 424 6.2E-8 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 VAPA_2c10000 5ca77087fdb1c1fae3bfd97216796b50 203 Pfam PF03352 Methyladenine glycosylase 16 186 1.0E-70 T 12-10-2018 IPR005019 Methyladenine glycosylase GO:0006284|GO:0008725 VAPA_2c10000 5ca77087fdb1c1fae3bfd97216796b50 203 Gene3D G3DSA:1.10.340.30 12 192 1.9E-74 T 12-10-2018 VAPA_2c10000 5ca77087fdb1c1fae3bfd97216796b50 203 SUPERFAMILY SSF48150 12 190 7.3E-71 T 12-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 VAPA_1c28130 1a207de3e1d00146192c6d683c77cebe 399 Pfam PF06779 Uncharacterised MFS-type transporter YbfB 22 386 1.1E-95 T 12-10-2018 IPR010645 Uncharacterised MFS-type transporter YbfB VAPA_1c28130 1a207de3e1d00146192c6d683c77cebe 399 SUPERFAMILY SSF103473 8 395 4.58E-26 T 12-10-2018 IPR036259 MFS transporter superfamily VAPA_1c28130 1a207de3e1d00146192c6d683c77cebe 399 Gene3D G3DSA:1.20.1250.20 3 397 8.5E-20 T 12-10-2018 VAPA_2c07520 cad857d0643d13fd2a0be623b8db6e8f 339 SUPERFAMILY SSF53474 41 332 1.5E-29 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_2c07520 cad857d0643d13fd2a0be623b8db6e8f 339 Gene3D G3DSA:3.40.50.1820 29 337 2.7E-30 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_2c07520 cad857d0643d13fd2a0be623b8db6e8f 339 Pfam PF12697 Alpha/beta hydrolase family 70 326 5.7E-9 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 VAPA_1c11310 38729aee3b553dec5b6b3b03d92fdfb5 337 Gene3D G3DSA:3.30.1300.30 60 313 7.3E-22 T 12-10-2018 VAPA_1c11310 38729aee3b553dec5b6b3b03d92fdfb5 337 PIRSF PIRSF002786 14 329 5.0E-60 T 12-10-2018 IPR005628 General secretion pathway protein K GO:0009306|GO:0016021 VAPA_1c11310 38729aee3b553dec5b6b3b03d92fdfb5 337 Gene3D G3DSA:1.10.40.60 131 227 7.3E-22 T 12-10-2018 IPR038072 GspK, central domain superfamily VAPA_1c11310 38729aee3b553dec5b6b3b03d92fdfb5 337 Pfam PF03934 Type II secretion system (T2SS), protein K 44 319 7.7E-60 T 12-10-2018 IPR005628 General secretion pathway protein K GO:0009306|GO:0016021 VAPA_1c11310 38729aee3b553dec5b6b3b03d92fdfb5 337 SUPERFAMILY SSF158544 134 225 3.66E-5 T 12-10-2018 IPR038072 GspK, central domain superfamily VAPA_1c11310 38729aee3b553dec5b6b3b03d92fdfb5 337 Gene3D G3DSA:1.10.40.60 228 288 7.3E-22 T 12-10-2018 IPR038072 GspK, central domain superfamily VAPA_1c11310 38729aee3b553dec5b6b3b03d92fdfb5 337 SUPERFAMILY SSF54523 59 326 1.88E-5 T 12-10-2018 VAPA_1c34480 a514671fecd697a93c47ec3e5a7d0d38 397 Gene3D G3DSA:1.20.1250.20 202 392 7.0E-34 T 12-10-2018 VAPA_1c34480 a514671fecd697a93c47ec3e5a7d0d38 397 Pfam PF12832 MFS_1 like family 24 369 2.9E-53 T 12-10-2018 IPR024989 Major facilitator superfamily associated domain VAPA_1c34480 a514671fecd697a93c47ec3e5a7d0d38 397 Gene3D G3DSA:1.20.1250.20 12 192 2.8E-18 T 12-10-2018 VAPA_1c34480 a514671fecd697a93c47ec3e5a7d0d38 397 SUPERFAMILY SSF103473 13 388 1.96E-46 T 12-10-2018 IPR036259 MFS transporter superfamily VAPA_1c34480 a514671fecd697a93c47ec3e5a7d0d38 397 PIRSF PIRSF004925 9 397 1.1E-81 T 12-10-2018 IPR026032 Probable 3-phenylpropionic acid transporter VAPA_1c02260 16215ef3f7843803acb6473f69651089 395 Gene3D G3DSA:3.90.850.10 151 374 2.1E-39 T 12-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 VAPA_1c02260 16215ef3f7843803acb6473f69651089 395 SUPERFAMILY SSF56529 166 373 2.22E-23 T 12-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 VAPA_1c26370 9de40e68b64003febf6a20ba092548b7 338 Gene3D G3DSA:3.90.180.10 10 335 1.1E-126 T 12-10-2018 VAPA_1c26370 9de40e68b64003febf6a20ba092548b7 338 Pfam PF00107 Zinc-binding dehydrogenase 160 295 3.7E-18 T 12-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 VAPA_1c26370 9de40e68b64003febf6a20ba092548b7 338 SUPERFAMILY SSF50129 1 142 1.56E-41 T 12-10-2018 IPR011032 GroES-like superfamily VAPA_1c26370 9de40e68b64003febf6a20ba092548b7 338 SUPERFAMILY SSF51735 125 303 2.71E-42 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c26370 9de40e68b64003febf6a20ba092548b7 338 SMART SM00829 17 335 1.3E-5 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 VAPA_1c26370 9de40e68b64003febf6a20ba092548b7 338 Pfam PF16884 N-terminal domain of oxidoreductase 5 108 5.8E-39 T 12-10-2018 VAPA_1c26370 9de40e68b64003febf6a20ba092548b7 338 Gene3D G3DSA:3.40.50.720 128 306 1.1E-126 T 12-10-2018 VAPA_1c36170 4903284a5eba14363fced22e8ecbbb18 159 SUPERFAMILY SSF56770 9 153 7.59E-67 T 12-10-2018 VAPA_1c36170 4903284a5eba14363fced22e8ecbbb18 159 ProSitePatterns PS01150 Respiratory-chain NADH dehydrogenase 20 Kd subunit signature. 118 134 - T 12-10-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VAPA_1c36170 4903284a5eba14363fced22e8ecbbb18 159 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 37 145 1.2E-21 T 12-10-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VAPA_1c36170 4903284a5eba14363fced22e8ecbbb18 159 TIGRFAM TIGR01957 nuoB_fam: NADH-quinone oxidoreductase, B subunit 11 152 1.7E-76 T 12-10-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VAPA_1c36170 4903284a5eba14363fced22e8ecbbb18 159 Hamap MF_01356 NAD(P)H-quinone oxidoreductase subunit K, chloroplastic [ndhK]. 1 151 42.142 T 12-10-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VAPA_1c36170 4903284a5eba14363fced22e8ecbbb18 159 Gene3D G3DSA:3.40.50.12280 1 159 2.7E-79 T 12-10-2018 VAPA_2c00870 e0f3f5d746e83c7e9a0c6493e1e06907 296 Gene3D G3DSA:3.90.25.10 143 267 6.5E-47 T 12-10-2018 VAPA_2c00870 e0f3f5d746e83c7e9a0c6493e1e06907 296 Gene3D G3DSA:3.40.50.720 5 268 6.5E-47 T 12-10-2018 VAPA_2c00870 e0f3f5d746e83c7e9a0c6493e1e06907 296 SUPERFAMILY SSF51735 5 257 1.55E-32 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_2c00870 e0f3f5d746e83c7e9a0c6493e1e06907 296 Pfam PF13460 NAD(P)H-binding 6 191 3.1E-15 T 12-10-2018 IPR016040 NAD(P)-binding domain VAPA_2c10890 296cc9b122f95d9bd927cbd46b29c69a 258 Pfam PF12833 Helix-turn-helix domain 190 256 1.7E-13 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 VAPA_2c10890 296cc9b122f95d9bd927cbd46b29c69a 258 SMART SM00342 183 254 4.5E-4 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 VAPA_2c10890 296cc9b122f95d9bd927cbd46b29c69a 258 Gene3D G3DSA:1.10.10.60 176 258 4.4E-12 T 12-10-2018 VAPA_1c41290 0439cf8eab576f62894ca042a8f6236d 110 ProDom PD336997 PRECURSOR SIGNAL MEMBRANE OUTER YNFD ESCHERICHIA EXPORTED PP0087 COLI PP0090 22 71 1.0E-8 T 12-10-2018 IPR010595 Protein of unknown function DUF1161 VAPA_1c41290 0439cf8eab576f62894ca042a8f6236d 110 Pfam PF06649 Protein of unknown function (DUF1161) 22 71 5.3E-19 T 12-10-2018 IPR010595 Protein of unknown function DUF1161 VAPA_1c26280 0f06ee3c26b2de04f047371f1645a13a 231 SMART SM00382 26 208 4.1E-6 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c26280 0f06ee3c26b2de04f047371f1645a13a 231 ProSitePatterns PS00211 ABC transporters family signature. 132 146 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_1c26280 0f06ee3c26b2de04f047371f1645a13a 231 Gene3D G3DSA:3.40.50.300 1 230 1.2E-55 T 12-10-2018 VAPA_1c26280 0f06ee3c26b2de04f047371f1645a13a 231 Pfam PF00005 ABC transporter 17 159 2.0E-28 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c26280 0f06ee3c26b2de04f047371f1645a13a 231 SUPERFAMILY SSF52540 2 222 1.23E-55 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c22360 b0f78bc722a215e0bdb32fc71a6f44f2 395 Gene3D G3DSA:3.40.50.2300 29 356 1.6E-90 T 12-10-2018 VAPA_1c22360 b0f78bc722a215e0bdb32fc71a6f44f2 395 Pfam PF13458 Periplasmic binding protein 28 361 1.6E-66 T 12-10-2018 IPR028081 Leucine-binding protein domain VAPA_1c22360 b0f78bc722a215e0bdb32fc71a6f44f2 395 Gene3D G3DSA:3.40.50.2300 146 365 1.6E-90 T 12-10-2018 VAPA_1c22360 b0f78bc722a215e0bdb32fc71a6f44f2 395 SUPERFAMILY SSF53822 28 384 1.72E-79 T 12-10-2018 IPR028082 Periplasmic binding protein-like I VAPA_1c36650 88b41a5b236c189ee9854e84c3a3746a 313 SUPERFAMILY SSF46689 249 298 1.03E-12 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 VAPA_1c36650 88b41a5b236c189ee9854e84c3a3746a 313 Gene3D G3DSA:1.10.10.60 196 245 7.7E-12 T 12-10-2018 VAPA_1c36650 88b41a5b236c189ee9854e84c3a3746a 313 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 265 280 1.3E-5 T 12-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 VAPA_1c36650 88b41a5b236c189ee9854e84c3a3746a 313 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 280 296 1.3E-5 T 12-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 VAPA_1c36650 88b41a5b236c189ee9854e84c3a3746a 313 SUPERFAMILY SSF46689 196 245 8.24E-5 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 VAPA_1c36650 88b41a5b236c189ee9854e84c3a3746a 313 SUPERFAMILY SSF51215 35 176 4.58E-7 T 12-10-2018 IPR037923 Transcription regulator HTH-like VAPA_1c36650 88b41a5b236c189ee9854e84c3a3746a 313 Gene3D G3DSA:1.10.10.60 246 301 4.0E-18 T 12-10-2018 VAPA_1c36650 88b41a5b236c189ee9854e84c3a3746a 313 Pfam PF12833 Helix-turn-helix domain 220 297 1.0E-18 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 VAPA_1c36650 88b41a5b236c189ee9854e84c3a3746a 313 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 250 292 - T 12-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 VAPA_1c36650 88b41a5b236c189ee9854e84c3a3746a 313 SMART SM00342 213 296 8.6E-27 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 VAPA_1c00410 6f6586461e3c6a53d3ab61b20a8c8c5a 202 Pfam PF00043 Glutathione S-transferase, C-terminal domain 103 189 4.4E-15 T 12-10-2018 IPR004046 Glutathione S-transferase, C-terminal VAPA_1c00410 6f6586461e3c6a53d3ab61b20a8c8c5a 202 Gene3D G3DSA:3.40.30.10 3 195 3.8E-70 T 12-10-2018 VAPA_1c00410 6f6586461e3c6a53d3ab61b20a8c8c5a 202 Gene3D G3DSA:1.20.1050.10 83 188 3.8E-70 T 12-10-2018 VAPA_1c00410 6f6586461e3c6a53d3ab61b20a8c8c5a 202 SUPERFAMILY SSF52833 1 78 1.57E-17 T 12-10-2018 IPR036249 Thioredoxin-like superfamily VAPA_1c00410 6f6586461e3c6a53d3ab61b20a8c8c5a 202 Pfam PF13417 Glutathione S-transferase, N-terminal domain 10 78 2.4E-7 T 12-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 VAPA_1c00410 6f6586461e3c6a53d3ab61b20a8c8c5a 202 SUPERFAMILY SSF47616 81 198 4.18E-31 T 12-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily VAPA_1c23340 d6ef2ff38b8c4a7d145db9edd75ac578 243 Gene3D G3DSA:3.40.50.1360 32 233 5.4E-72 T 12-10-2018 VAPA_1c23340 d6ef2ff38b8c4a7d145db9edd75ac578 243 Pfam PF06026 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) 68 236 6.7E-56 T 12-10-2018 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-5659996|Reactome: R-HSA-6791461|Reactome: R-HSA-71336 VAPA_1c23340 d6ef2ff38b8c4a7d145db9edd75ac578 243 Gene3D G3DSA:3.30.70.260 144 219 5.4E-72 T 12-10-2018 VAPA_1c23340 d6ef2ff38b8c4a7d145db9edd75ac578 243 TIGRFAM TIGR00021 rpiA: ribose 5-phosphate isomerase A 26 237 3.2E-65 T 12-10-2018 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-5659996|Reactome: R-HSA-6791461|Reactome: R-HSA-71336 VAPA_1c23340 d6ef2ff38b8c4a7d145db9edd75ac578 243 SUPERFAMILY SSF100950 21 166 7.44E-43 T 12-10-2018 IPR037171 NagB/RpiA transferase-like VAPA_1c23340 d6ef2ff38b8c4a7d145db9edd75ac578 243 Hamap MF_00170 Ribose-5-phosphate isomerase A [rpiA]. 22 240 31.603 T 12-10-2018 IPR020672 Ribose-5-phosphate isomerase, type A, subgroup GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-5659996|Reactome: R-HSA-6791461|Reactome: R-HSA-71336 VAPA_1c23340 d6ef2ff38b8c4a7d145db9edd75ac578 243 SUPERFAMILY SSF75445 145 221 2.49E-20 T 12-10-2018 VAPA_1c37330 4c0150fbc52e5335c84d6acb44d29bc6 98 Pfam PF13239 2TM domain 16 74 1.1E-16 T 12-10-2018 IPR025698 2TM domain VAPA_1c43350 5518877fcd1bcf817e75f5ce4c0fd70e 253 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 180 200 1.1E-65 T 12-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 VAPA_1c43350 5518877fcd1bcf817e75f5ce4c0fd70e 253 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 225 250 1.1E-65 T 12-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 VAPA_1c43350 5518877fcd1bcf817e75f5ce4c0fd70e 253 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 201 222 1.1E-65 T 12-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 VAPA_1c43350 5518877fcd1bcf817e75f5ce4c0fd70e 253 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 72 92 1.1E-65 T 12-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 VAPA_1c43350 5518877fcd1bcf817e75f5ce4c0fd70e 253 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 53 72 1.1E-65 T 12-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 VAPA_1c43350 5518877fcd1bcf817e75f5ce4c0fd70e 253 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 92 111 1.1E-65 T 12-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 VAPA_1c43350 5518877fcd1bcf817e75f5ce4c0fd70e 253 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 123 137 2.5E-31 T 12-10-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 VAPA_1c43350 5518877fcd1bcf817e75f5ce4c0fd70e 253 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 151 163 2.5E-31 T 12-10-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 VAPA_1c43350 5518877fcd1bcf817e75f5ce4c0fd70e 253 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 241 251 2.5E-31 T 12-10-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 VAPA_1c43350 5518877fcd1bcf817e75f5ce4c0fd70e 253 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 111 123 2.5E-31 T 12-10-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 VAPA_1c43350 5518877fcd1bcf817e75f5ce4c0fd70e 253 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 173 185 2.5E-31 T 12-10-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 VAPA_1c43350 5518877fcd1bcf817e75f5ce4c0fd70e 253 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 51 60 2.5E-31 T 12-10-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 VAPA_1c43350 5518877fcd1bcf817e75f5ce4c0fd70e 253 Pfam PF00813 FliP family 55 247 1.2E-78 T 12-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 VAPA_1c43350 5518877fcd1bcf817e75f5ce4c0fd70e 253 TIGRFAM TIGR01103 fliP: flagellar biosynthetic protein FliP 55 251 2.5E-90 T 12-10-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 VAPA_1c43350 5518877fcd1bcf817e75f5ce4c0fd70e 253 ProSitePatterns PS01060 Flagella transport protein fliP family signature 1. 180 195 - T 12-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 VAPA_1c43350 5518877fcd1bcf817e75f5ce4c0fd70e 253 ProSitePatterns PS01061 Flagella transport protein fliP family signature 2. 228 240 - T 12-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 VAPA_1c07950 f83cb5db0a925a7c7250eb95305a632a 805 Gene3D G3DSA:1.25.40.10 289 516 1.3E-5 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 VAPA_1c07950 f83cb5db0a925a7c7250eb95305a632a 805 TIGRFAM TIGR03939 PGA_TPR_OMP: poly-beta-1,6 N-acetyl-D-glucosamine export porin PgaA 171 802 1.2E-116 T 12-10-2018 IPR023870 Poly-beta-1,6 N-acetyl-D-glucosamine export porin PgaA GO:1901515 VAPA_1c07950 f83cb5db0a925a7c7250eb95305a632a 805 SUPERFAMILY SSF48452 356 502 4.22E-5 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 VAPA_1c06640 5420a3be025154e40e437e14bb1a6982 336 PIRSF PIRSF006470 1 333 3.9E-75 T 12-10-2018 IPR004682 TRAP transporter solute receptor, DctP family GO:0030288|GO:0055085 VAPA_1c06640 5420a3be025154e40e437e14bb1a6982 336 TIGRFAM TIGR00787 dctP: TRAP transporter solute receptor, DctP family 37 288 2.1E-66 T 12-10-2018 IPR004682 TRAP transporter solute receptor, DctP family GO:0030288|GO:0055085 VAPA_1c06640 5420a3be025154e40e437e14bb1a6982 336 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 37 310 1.6E-72 T 12-10-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0030288|GO:0055085 VAPA_1c06640 5420a3be025154e40e437e14bb1a6982 336 Gene3D G3DSA:3.40.190.170 28 336 2.9E-103 T 12-10-2018 IPR038404 TRAP transporter solute receptor DctP superfamily VAPA_1c18170 54af1209a171fdf9e278d6e6f6af7513 303 SMART SM01130 10 301 2.1E-74 T 12-10-2018 IPR002220 DapA-like GO:0016829 VAPA_1c18170 54af1209a171fdf9e278d6e6f6af7513 303 TIGRFAM TIGR03249 KdgD: 5-dehydro-4-deoxyglucarate dehydratase 3 299 1.5E-128 T 12-10-2018 IPR017655 5-dehydro-4-deoxyglucarate dehydratase GO:0016052|GO:0047448 KEGG: 00053+4.2.1.41|MetaCyc: PWY-6486|MetaCyc: PWY-6497|MetaCyc: PWY-6499|MetaCyc: PWY-6501 VAPA_1c18170 54af1209a171fdf9e278d6e6f6af7513 303 Gene3D G3DSA:3.20.20.70 1 301 2.2E-92 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 VAPA_1c18170 54af1209a171fdf9e278d6e6f6af7513 303 Pfam PF00701 Dihydrodipicolinate synthetase family 12 299 3.2E-51 T 12-10-2018 IPR002220 DapA-like GO:0016829 VAPA_1c18170 54af1209a171fdf9e278d6e6f6af7513 303 PIRSF PIRSF001365 6 303 4.1E-55 T 12-10-2018 IPR002220 DapA-like GO:0016829 VAPA_1c18170 54af1209a171fdf9e278d6e6f6af7513 303 Hamap MF_00694 Probable 5-dehydro-4-deoxyglucarate dehydratase. 10 301 43.487 T 12-10-2018 IPR017655 5-dehydro-4-deoxyglucarate dehydratase GO:0016052|GO:0047448 KEGG: 00053+4.2.1.41|MetaCyc: PWY-6486|MetaCyc: PWY-6497|MetaCyc: PWY-6499|MetaCyc: PWY-6501 VAPA_1c18170 54af1209a171fdf9e278d6e6f6af7513 303 SUPERFAMILY SSF51569 10 300 3.04E-65 T 12-10-2018 VAPA_1c30780 d53b870c4d340f54de435e11d9bfb051 144 Pfam PF01479 S4 domain 5 50 3.6E-9 T 12-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VAPA_1c30780 d53b870c4d340f54de435e11d9bfb051 144 PIRSF PIRSF016821 1 128 4.4E-41 T 12-10-2018 IPR025708 Heat shock protein 15 GO:0003677|GO:0003727|GO:0034605|GO:0043023 VAPA_1c30780 d53b870c4d340f54de435e11d9bfb051 144 Gene3D G3DSA:3.10.290.10 1 102 3.9E-34 T 12-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 VAPA_1c30780 d53b870c4d340f54de435e11d9bfb051 144 SMART SM00363 4 67 6.1E-4 T 12-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VAPA_1c30780 d53b870c4d340f54de435e11d9bfb051 144 SUPERFAMILY SSF55174 2 99 9.42E-27 T 12-10-2018 VAPA_2c09320 44a37440eec570d14a9eec9659f99821 291 Pfam PF02798 Glutathione S-transferase, N-terminal domain 74 134 2.0E-4 T 12-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 VAPA_2c09320 44a37440eec570d14a9eec9659f99821 291 Gene3D G3DSA:1.20.1050.10 140 255 6.9E-104 T 12-10-2018 VAPA_2c09320 44a37440eec570d14a9eec9659f99821 291 Gene3D G3DSA:3.40.30.10 26 261 6.9E-104 T 12-10-2018 VAPA_2c09320 44a37440eec570d14a9eec9659f99821 291 SUPERFAMILY SSF47616 140 284 8.6E-29 T 12-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily VAPA_2c09320 44a37440eec570d14a9eec9659f99821 291 Pfam PF13410 Glutathione S-transferase, C-terminal domain 182 251 7.1E-9 T 12-10-2018 VAPA_2c09320 44a37440eec570d14a9eec9659f99821 291 SUPERFAMILY SSF52833 46 137 8.78E-17 T 12-10-2018 IPR036249 Thioredoxin-like superfamily VAPA_2c06640 251dc8131018333b35eb221e7be73125 317 Gene3D G3DSA:3.40.50.2300 135 269 4.4E-94 T 12-10-2018 VAPA_2c06640 251dc8131018333b35eb221e7be73125 317 Gene3D G3DSA:3.40.50.2300 32 315 4.4E-94 T 12-10-2018 VAPA_2c06640 251dc8131018333b35eb221e7be73125 317 Pfam PF13407 Periplasmic binding protein domain 32 289 3.7E-58 T 12-10-2018 IPR025997 Periplasmic binding protein VAPA_2c06640 251dc8131018333b35eb221e7be73125 317 SUPERFAMILY SSF53822 32 315 1.91E-72 T 12-10-2018 IPR028082 Periplasmic binding protein-like I VAPA_1c00760 2da6b51da100371fa202326f3ae8137f 455 Gene3D G3DSA:1.20.1250.20 15 452 2.5E-84 T 12-10-2018 VAPA_1c00760 2da6b51da100371fa202326f3ae8137f 455 Pfam PF00083 Sugar (and other) transporter 37 450 8.6E-44 T 12-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 VAPA_1c00760 2da6b51da100371fa202326f3ae8137f 455 ProSitePatterns PS00217 Sugar transport proteins signature 2. 116 141 - T 12-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 VAPA_1c00760 2da6b51da100371fa202326f3ae8137f 455 SUPERFAMILY SSF103473 7 449 7.19E-84 T 12-10-2018 IPR036259 MFS transporter superfamily VAPA_1c31580 3fd059e5ee92de2260c3ac6448e15829 458 SUPERFAMILY SSF47323 320 455 1.83E-32 T 12-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 VAPA_1c31580 3fd059e5ee92de2260c3ac6448e15829 458 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 26 37 1.2E-27 T 12-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 VAPA_1c31580 3fd059e5ee92de2260c3ac6448e15829 458 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 226 247 1.2E-27 T 12-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 VAPA_1c31580 3fd059e5ee92de2260c3ac6448e15829 458 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 195 213 1.2E-27 T 12-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 VAPA_1c31580 3fd059e5ee92de2260c3ac6448e15829 458 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 62 71 1.2E-27 T 12-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 VAPA_1c31580 3fd059e5ee92de2260c3ac6448e15829 458 TIGRFAM TIGR00435 cysS: cysteine--tRNA ligase 3 455 3.2E-164 T 12-10-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 VAPA_1c31580 3fd059e5ee92de2260c3ac6448e15829 458 Pfam PF01406 tRNA synthetases class I (C) catalytic domain 16 316 8.8E-126 T 12-10-2018 IPR032678 tRNA synthetases class I, catalytic domain KEGG: 00970+6.1.1.16 VAPA_1c31580 3fd059e5ee92de2260c3ac6448e15829 458 SUPERFAMILY SSF52374 3 316 2.1E-94 T 12-10-2018 VAPA_1c31580 3fd059e5ee92de2260c3ac6448e15829 458 Hamap MF_00041 Cysteine--tRNA ligase [cysS]. 3 457 37.423 T 12-10-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 VAPA_1c31580 3fd059e5ee92de2260c3ac6448e15829 458 Gene3D G3DSA:1.20.120.640 311 456 9.1E-38 T 12-10-2018 VAPA_1c31580 3fd059e5ee92de2260c3ac6448e15829 458 Pfam PF09190 DALR domain 346 401 1.5E-14 T 12-10-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 VAPA_1c31580 3fd059e5ee92de2260c3ac6448e15829 458 SMART SM00840 346 401 2.8E-19 T 12-10-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 VAPA_1c31580 3fd059e5ee92de2260c3ac6448e15829 458 Gene3D G3DSA:3.40.50.620 1 309 1.2E-128 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold VAPA_2c10720 d5024d0be1751897faefcfdbd7b4f22e 794 SUPERFAMILY SSF53098 7 398 3.21E-84 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily VAPA_2c10720 d5024d0be1751897faefcfdbd7b4f22e 794 SUPERFAMILY SSF56672 394 786 7.23E-105 T 12-10-2018 VAPA_2c10720 d5024d0be1751897faefcfdbd7b4f22e 794 Gene3D G3DSA:3.30.420.10 155 356 1.0E-67 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 VAPA_2c10720 d5024d0be1751897faefcfdbd7b4f22e 794 ProSitePatterns PS00116 DNA polymerase family B signature. 552 560 - T 12-10-2018 IPR017964 DNA-directed DNA polymerase, family B, conserved site GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 VAPA_2c10720 d5024d0be1751897faefcfdbd7b4f22e 794 Gene3D G3DSA:3.30.70.2250 43 109 1.3E-50 T 12-10-2018 VAPA_2c10720 d5024d0be1751897faefcfdbd7b4f22e 794 Pfam PF00136 DNA polymerase family B 390 745 3.9E-37 T 12-10-2018 IPR006134 DNA-directed DNA polymerase, family B, multifunctional domain GO:0000166|GO:0003677 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 VAPA_2c10720 d5024d0be1751897faefcfdbd7b4f22e 794 Gene3D G3DSA:3.90.1600.10 357 449 7.2E-31 T 12-10-2018 IPR023211 DNA polymerase, palm domain superfamily KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 VAPA_2c10720 d5024d0be1751897faefcfdbd7b4f22e 794 Gene3D G3DSA:3.90.1600.10 472 643 4.9E-47 T 12-10-2018 IPR023211 DNA polymerase, palm domain superfamily KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 VAPA_2c10720 d5024d0be1751897faefcfdbd7b4f22e 794 SMART SM00486 152 564 1.7E-65 T 12-10-2018 IPR006172 DNA-directed DNA polymerase, family B GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 VAPA_2c10720 d5024d0be1751897faefcfdbd7b4f22e 794 Gene3D G3DSA:1.10.132.60 650 794 1.5E-53 T 12-10-2018 VAPA_2c10720 d5024d0be1751897faefcfdbd7b4f22e 794 Gene3D G3DSA:2.40.50.590 8 152 1.3E-50 T 12-10-2018 VAPA_2c10720 d5024d0be1751897faefcfdbd7b4f22e 794 PRINTS PR00106 DNA-directed DNA-polymerase family B signature 498 510 2.4E-8 T 12-10-2018 IPR006172 DNA-directed DNA polymerase, family B GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 VAPA_2c10720 d5024d0be1751897faefcfdbd7b4f22e 794 PRINTS PR00106 DNA-directed DNA-polymerase family B signature 424 437 2.4E-8 T 12-10-2018 IPR006172 DNA-directed DNA polymerase, family B GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 VAPA_2c10720 d5024d0be1751897faefcfdbd7b4f22e 794 PRINTS PR00106 DNA-directed DNA-polymerase family B signature 550 558 2.4E-8 T 12-10-2018 IPR006172 DNA-directed DNA polymerase, family B GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 VAPA_2c10720 d5024d0be1751897faefcfdbd7b4f22e 794 Pfam PF03104 DNA polymerase family B, exonuclease domain 81 305 6.7E-16 T 12-10-2018 IPR006133 DNA-directed DNA polymerase, family B, exonuclease domain KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 VAPA_2c08810 006305b3f6def92ec397edb5ca0e111b 322 SUPERFAMILY SSF53474 48 321 1.18E-63 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_2c08810 006305b3f6def92ec397edb5ca0e111b 322 Pfam PF00326 Prolyl oligopeptidase family 232 321 2.3E-5 T 12-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 VAPA_2c08810 006305b3f6def92ec397edb5ca0e111b 322 PRINTS PR00412 Epoxide hydrolase signature 263 279 1.4E-5 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 VAPA_2c08810 006305b3f6def92ec397edb5ca0e111b 322 PRINTS PR00412 Epoxide hydrolase signature 96 111 1.4E-5 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 VAPA_2c08810 006305b3f6def92ec397edb5ca0e111b 322 PRINTS PR00412 Epoxide hydrolase signature 76 94 1.4E-5 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 VAPA_2c08810 006305b3f6def92ec397edb5ca0e111b 322 PRINTS PR00111 Alpha/beta hydrolase fold signature 140 153 1.1E-11 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 VAPA_2c08810 006305b3f6def92ec397edb5ca0e111b 322 PRINTS PR00111 Alpha/beta hydrolase fold signature 96 111 1.1E-11 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 VAPA_2c08810 006305b3f6def92ec397edb5ca0e111b 322 PRINTS PR00111 Alpha/beta hydrolase fold signature 265 279 1.1E-11 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 VAPA_2c08810 006305b3f6def92ec397edb5ca0e111b 322 Pfam PF00561 alpha/beta hydrolase fold 70 175 1.1E-19 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 VAPA_2c08810 006305b3f6def92ec397edb5ca0e111b 322 Gene3D G3DSA:3.40.50.1820 51 321 1.4E-79 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c29810 dd9dcfd072b2e7f42492fcd63d088b2c 395 SUPERFAMILY SSF53383 2 395 1.61E-101 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase VAPA_1c29810 dd9dcfd072b2e7f42492fcd63d088b2c 395 Gene3D G3DSA:3.90.1150.10 15 395 1.6E-131 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 VAPA_1c29810 dd9dcfd072b2e7f42492fcd63d088b2c 395 Pfam PF00155 Aminotransferase class I and II 42 391 8.2E-41 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 VAPA_1c29810 dd9dcfd072b2e7f42492fcd63d088b2c 395 Gene3D G3DSA:3.40.640.10 62 285 1.6E-131 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 VAPA_2c12370 b47f90a82ffdc495e08b07811344e7c0 720 Gene3D G3DSA:3.40.50.970 435 610 5.6E-13 T 12-10-2018 VAPA_2c12370 b47f90a82ffdc495e08b07811344e7c0 720 SUPERFAMILY SSF52518 411 593 3.57E-24 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold VAPA_2c12370 b47f90a82ffdc495e08b07811344e7c0 720 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 443 585 3.3E-18 T 12-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 VAPA_2c12370 b47f90a82ffdc495e08b07811344e7c0 720 SUPERFAMILY SSF52518 20 245 2.06E-28 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold VAPA_2c12370 b47f90a82ffdc495e08b07811344e7c0 720 Gene3D G3DSA:3.40.50.970 3 203 1.2E-24 T 12-10-2018 VAPA_1c00420 cbcd924fe5f45c3f01f5a84d28400afa 61 PIRSF PIRSF036466 1 55 2.8E-17 T 12-10-2018 IPR009760 Protein of unknown function DUF1328 GO:0005886 VAPA_1c00420 cbcd924fe5f45c3f01f5a84d28400afa 61 Hamap MF_01361 UPF0391 membrane protein YtjA [ytjA]. 1 53 18.567 T 12-10-2018 IPR009760 Protein of unknown function DUF1328 GO:0005886 VAPA_1c00420 cbcd924fe5f45c3f01f5a84d28400afa 61 Pfam PF07043 Protein of unknown function (DUF1328) 6 44 6.9E-14 T 12-10-2018 IPR009760 Protein of unknown function DUF1328 GO:0005886 VAPA_2c12270 2d63431ec9107d93122c059cb66db43e 446 Pfam PF13657 HipA N-terminal domain 10 110 4.4E-21 T 12-10-2018 IPR017508 HipA, N-terminal subdomain 1 VAPA_2c12270 2d63431ec9107d93122c059cb66db43e 446 Pfam PF07804 HipA-like C-terminal domain 158 406 1.9E-50 T 12-10-2018 IPR012893 HipA-like, C-terminal VAPA_2c12270 2d63431ec9107d93122c059cb66db43e 446 TIGRFAM TIGR03071 couple_hipA: HipA N-terminal domain 10 110 2.9E-27 T 12-10-2018 IPR017508 HipA, N-terminal subdomain 1 VAPA_1c50060 72e561c3a94518628a72d6a877bc3770 350 SUPERFAMILY SSF53474 36 339 9.81E-34 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c50060 72e561c3a94518628a72d6a877bc3770 350 PIRSF PIRSF005211 5 350 2.4E-90 T 12-10-2018 IPR012020 AB hydrolase 4 family VAPA_1c50060 72e561c3a94518628a72d6a877bc3770 350 Gene3D G3DSA:3.40.50.1820 49 316 1.9E-19 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_2c03750 5ae4d149e320972bd6395c2e140e018a 348 SUPERFAMILY SSF53850 41 265 6.95E-36 T 12-10-2018 VAPA_2c03750 5ae4d149e320972bd6395c2e140e018a 348 Gene3D G3DSA:3.40.190.10 121 219 2.7E-43 T 12-10-2018 VAPA_2c03750 5ae4d149e320972bd6395c2e140e018a 348 Gene3D G3DSA:1.10.8.450 255 286 2.7E-43 T 12-10-2018 VAPA_2c03750 5ae4d149e320972bd6395c2e140e018a 348 Pfam PF09084 NMT1/THI5 like 81 252 1.3E-7 T 12-10-2018 IPR015168 SsuA/THI5-like VAPA_2c03750 5ae4d149e320972bd6395c2e140e018a 348 Gene3D G3DSA:3.40.190.10 57 254 2.7E-43 T 12-10-2018 VAPA_1c20520 1f716d68903d10e3f9973d28fdb79e0c 523 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 108 233 9.1E-11 T 12-10-2018 IPR000014 PAS domain VAPA_1c20520 1f716d68903d10e3f9973d28fdb79e0c 523 SMART SM00387 402 514 9.8E-23 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase VAPA_1c20520 1f716d68903d10e3f9973d28fdb79e0c 523 SUPERFAMILY SSF55785 102 221 8.2E-15 T 12-10-2018 IPR035965 PAS domain superfamily VAPA_1c20520 1f716d68903d10e3f9973d28fdb79e0c 523 PRINTS PR00344 Bacterial sensor protein C-terminal signature 473 491 3.3E-7 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c20520 1f716d68903d10e3f9973d28fdb79e0c 523 PRINTS PR00344 Bacterial sensor protein C-terminal signature 444 458 3.3E-7 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c20520 1f716d68903d10e3f9973d28fdb79e0c 523 PRINTS PR00344 Bacterial sensor protein C-terminal signature 498 511 3.3E-7 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c20520 1f716d68903d10e3f9973d28fdb79e0c 523 SUPERFAMILY SSF55785 20 90 1.19E-9 T 12-10-2018 IPR035965 PAS domain superfamily VAPA_1c20520 1f716d68903d10e3f9973d28fdb79e0c 523 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 403 512 5.1E-14 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase VAPA_1c20520 1f716d68903d10e3f9973d28fdb79e0c 523 Pfam PF08448 PAS fold 116 228 4.5E-11 T 12-10-2018 IPR013656 PAS fold-4 VAPA_1c20520 1f716d68903d10e3f9973d28fdb79e0c 523 Pfam PF08448 PAS fold 21 69 2.2E-7 T 12-10-2018 IPR013656 PAS fold-4 VAPA_1c20520 1f716d68903d10e3f9973d28fdb79e0c 523 Gene3D G3DSA:3.30.450.20 97 240 5.6E-22 T 12-10-2018 VAPA_1c20520 1f716d68903d10e3f9973d28fdb79e0c 523 SUPERFAMILY SSF55874 363 512 2.75E-28 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_1c20520 1f716d68903d10e3f9973d28fdb79e0c 523 SMART SM00091 15 82 5.8E-5 T 12-10-2018 IPR000014 PAS domain VAPA_1c20520 1f716d68903d10e3f9973d28fdb79e0c 523 SMART SM00091 110 177 4.8 T 12-10-2018 IPR000014 PAS domain VAPA_1c20520 1f716d68903d10e3f9973d28fdb79e0c 523 Gene3D G3DSA:3.30.450.20 4 93 4.1E-9 T 12-10-2018 VAPA_1c20520 1f716d68903d10e3f9973d28fdb79e0c 523 Gene3D G3DSA:3.30.565.10 362 518 1.1E-28 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_1c41190 19c03b170fd0dc23f19fee4f5e2dfa93 276 Pfam PF01774 UreD urease accessory protein 45 249 6.3E-39 T 12-10-2018 IPR002669 Urease accessory protein UreD GO:0006807|GO:0016151 VAPA_1c41190 19c03b170fd0dc23f19fee4f5e2dfa93 276 Hamap MF_01384 Urease accessory protein UreD [ureD]. 3 260 26.638 T 12-10-2018 IPR002669 Urease accessory protein UreD GO:0006807|GO:0016151 VAPA_1c01390 05d0def6c9eed20ebb4aa632e50f14cc 254 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 22 253 1.2E-43 T 12-10-2018 VAPA_1c01390 05d0def6c9eed20ebb4aa632e50f14cc 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 164 183 9.2E-8 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c01390 05d0def6c9eed20ebb4aa632e50f14cc 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 88 99 9.2E-8 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c01390 05d0def6c9eed20ebb4aa632e50f14cc 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 144 152 9.2E-8 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c01390 05d0def6c9eed20ebb4aa632e50f14cc 254 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 151 179 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 VAPA_1c01390 05d0def6c9eed20ebb4aa632e50f14cc 254 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 12 199 7.3E-4 T 12-10-2018 VAPA_1c01390 05d0def6c9eed20ebb4aa632e50f14cc 254 Gene3D G3DSA:3.40.50.720 3 253 6.1E-67 T 12-10-2018 VAPA_1c01390 05d0def6c9eed20ebb4aa632e50f14cc 254 SUPERFAMILY SSF51735 7 253 5.2E-61 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c01390 05d0def6c9eed20ebb4aa632e50f14cc 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 13 30 2.8E-30 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c01390 05d0def6c9eed20ebb4aa632e50f14cc 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 164 183 2.8E-30 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c01390 05d0def6c9eed20ebb4aa632e50f14cc 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 88 99 2.8E-30 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c01390 05d0def6c9eed20ebb4aa632e50f14cc 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 184 201 2.8E-30 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c01390 05d0def6c9eed20ebb4aa632e50f14cc 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 217 237 2.8E-30 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c01390 05d0def6c9eed20ebb4aa632e50f14cc 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 138 154 2.8E-30 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c24450 91d14073b5f0fd3e307c24d99dd21648 288 SUPERFAMILY SSF55729 50 261 6.18E-41 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase VAPA_1c24450 91d14073b5f0fd3e307c24d99dd21648 288 Pfam PF13444 Acetyltransferase (GNAT) domain 67 167 1.0E-31 T 12-10-2018 VAPA_1c24450 91d14073b5f0fd3e307c24d99dd21648 288 Gene3D G3DSA:3.40.630.30 52 198 7.9E-26 T 12-10-2018 VAPA_1c30070 68ae17178da55dbec88c5e9130e7693f 110 SUPERFAMILY SSF102829 3 69 3.14E-17 T 12-10-2018 IPR036192 Cell division protein ZapA-like superfamily VAPA_1c30070 68ae17178da55dbec88c5e9130e7693f 110 Gene3D G3DSA:1.10.20.30 1 45 2.2E-10 T 12-10-2018 VAPA_1c30070 68ae17178da55dbec88c5e9130e7693f 110 Pfam PF05164 Cell division protein ZapA 4 100 1.8E-20 T 12-10-2018 IPR007838 Cell division protein ZapA-like VAPA_1c14540 08d494a40120ad1bd9a3b6d3b6831626 366 Gene3D G3DSA:3.30.565.10 228 365 3.0E-11 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_1c14540 08d494a40120ad1bd9a3b6d3b6831626 366 SUPERFAMILY SSF55874 230 341 3.01E-9 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_1c14540 08d494a40120ad1bd9a3b6d3b6831626 366 Pfam PF06580 Histidine kinase 174 252 3.2E-23 T 12-10-2018 IPR010559 Signal transduction histidine kinase, internal region GO:0000155|GO:0000160|GO:0016021 VAPA_1c33800 c4510e30cd490ec07e15eeb5afb09f57 502 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 275 286 - T 12-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 VAPA_1c33800 c4510e30cd490ec07e15eeb5afb09f57 502 SUPERFAMILY SSF53720 2 485 3.53E-149 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 VAPA_1c33800 c4510e30cd490ec07e15eeb5afb09f57 502 TIGRFAM TIGR01722 MMSDH: methylmalonate-semialdehyde dehydrogenase (acylating) 6 486 9.4E-208 T 12-10-2018 IPR010061 Methylmalonate-semialdehyde dehydrogenase GO:0004491|GO:0055114 KEGG: 00280+1.2.1.27|KEGG: 00640+1.2.1.27|MetaCyc: PWY-5642|Reactome: R-HSA-70895 VAPA_1c33800 c4510e30cd490ec07e15eeb5afb09f57 502 Gene3D G3DSA:3.40.309.10 250 455 3.9E-152 T 12-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 VAPA_1c33800 c4510e30cd490ec07e15eeb5afb09f57 502 Pfam PF00171 Aldehyde dehydrogenase family 19 482 1.4E-143 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 VAPA_1c33800 c4510e30cd490ec07e15eeb5afb09f57 502 Gene3D G3DSA:3.40.605.10 24 463 3.9E-152 T 12-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 VAPA_2c06750 e6aa124d0431e30798588800554114f4 318 Gene3D G3DSA:3.40.190.150 23 308 3.8E-100 T 12-10-2018 VAPA_2c06750 e6aa124d0431e30798588800554114f4 318 PIRSF PIRSF017082 1 318 5.9E-70 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_2c06750 e6aa124d0431e30798588800554114f4 318 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 41 314 1.7E-76 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_2c06750 e6aa124d0431e30798588800554114f4 318 SUPERFAMILY SSF53850 105 273 1.14E-13 T 12-10-2018 VAPA_2c06750 e6aa124d0431e30798588800554114f4 318 Gene3D G3DSA:3.40.190.10 120 243 3.8E-100 T 12-10-2018 VAPA_1c19200 b5c1e5d3c808bbddc8cdbacd48607ace 83 TIGRFAM TIGR01682 moaD: molybdopterin converting factor, subunit 1 3 83 3.5E-19 T 12-10-2018 VAPA_1c19200 b5c1e5d3c808bbddc8cdbacd48607ace 83 Gene3D G3DSA:3.10.20.30 2 83 8.0E-20 T 12-10-2018 IPR012675 Beta-grasp domain superfamily VAPA_1c19200 b5c1e5d3c808bbddc8cdbacd48607ace 83 SUPERFAMILY SSF54285 1 81 2.06E-17 T 12-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp VAPA_1c19200 b5c1e5d3c808bbddc8cdbacd48607ace 83 Pfam PF02597 ThiS family 5 83 3.7E-15 T 12-10-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 VAPA_2c03560 93cc99ac3fc1e78c8032f0de0c6ebcb5 216 Pfam PF12261 Thermostable hemolysin 30 198 2.1E-55 T 12-10-2018 IPR022050 Thermostable hemolysin VAPA_2c03560 93cc99ac3fc1e78c8032f0de0c6ebcb5 216 SUPERFAMILY SSF55729 37 164 1.58E-7 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase VAPA_2c03480 700a1b8ed2b044d8de40cfba186ff890 323 SUPERFAMILY SSF64182 5 298 2.22E-29 T 12-10-2018 IPR038763 DHH phosphoesterase superfamily VAPA_1c04190 75b9a834c0ecbc4f3d62f80a77e69452 361 Gene3D G3DSA:2.60.120.10 14 361 3.3E-120 T 12-10-2018 IPR014710 RmlC-like jelly roll fold VAPA_1c04190 75b9a834c0ecbc4f3d62f80a77e69452 361 SUPERFAMILY SSF51182 17 359 1.06E-107 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily VAPA_1c04190 75b9a834c0ecbc4f3d62f80a77e69452 361 TIGRFAM TIGR02272 gentisate_1_2: gentisate 1,2-dioxygenase 18 356 3.7E-161 T 12-10-2018 IPR011960 Gentisate 1,2-dioxygenase VAPA_1c04190 75b9a834c0ecbc4f3d62f80a77e69452 361 Pfam PF07883 Cupin domain 101 162 2.6E-20 T 12-10-2018 IPR013096 Cupin 2, conserved barrel VAPA_1c32600 964423976c5d1e9027fd125142bea62a 327 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 50 324 4.1E-66 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c32600 964423976c5d1e9027fd125142bea62a 327 PIRSF PIRSF017082 2 327 1.7E-71 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c32600 964423976c5d1e9027fd125142bea62a 327 Gene3D G3DSA:3.40.190.10 130 252 2.0E-99 T 12-10-2018 VAPA_1c32600 964423976c5d1e9027fd125142bea62a 327 SUPERFAMILY SSF53850 121 281 7.36E-11 T 12-10-2018 VAPA_1c32600 964423976c5d1e9027fd125142bea62a 327 Gene3D G3DSA:3.40.190.150 30 317 2.0E-99 T 12-10-2018 VAPA_1c51410 0883062f521f7e36bdac53cb92600f83 342 Pfam PF00005 ABC transporter 19 161 6.7E-36 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c51410 0883062f521f7e36bdac53cb92600f83 342 SUPERFAMILY SSF50331 239 334 8.5E-7 T 12-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal VAPA_1c51410 0883062f521f7e36bdac53cb92600f83 342 Pfam PF08402 TOBE domain 272 328 1.0E-5 T 12-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 VAPA_1c51410 0883062f521f7e36bdac53cb92600f83 342 SMART SM00382 28 211 2.0E-15 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c51410 0883062f521f7e36bdac53cb92600f83 342 Gene3D G3DSA:3.40.50.300 1 237 2.6E-76 T 12-10-2018 VAPA_1c51410 0883062f521f7e36bdac53cb92600f83 342 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_1c51410 0883062f521f7e36bdac53cb92600f83 342 SUPERFAMILY SSF52540 4 241 3.41E-82 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c27700 b60ae0f2d2f4e2a46a592514bbcea987 325 SMART SM00833 228 322 1.2E-21 T 12-10-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal VAPA_1c27700 b60ae0f2d2f4e2a46a592514bbcea987 325 SUPERFAMILY SSF90002 228 322 1.44E-24 T 12-10-2018 VAPA_1c27700 b60ae0f2d2f4e2a46a592514bbcea987 325 Gene3D G3DSA:3.40.50.300 2 205 9.1E-74 T 12-10-2018 VAPA_1c27700 b60ae0f2d2f4e2a46a592514bbcea987 325 SUPERFAMILY SSF52540 4 207 4.7E-43 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c27700 b60ae0f2d2f4e2a46a592514bbcea987 325 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 5 185 1.5E-56 T 12-10-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain VAPA_1c27700 b60ae0f2d2f4e2a46a592514bbcea987 325 Gene3D G3DSA:3.30.1220.10 206 322 5.4E-33 T 12-10-2018 IPR036627 CobW-like, C-terminal domain superfamily VAPA_1c27700 b60ae0f2d2f4e2a46a592514bbcea987 325 Pfam PF07683 Cobalamin synthesis protein cobW C-terminal domain 228 322 7.5E-23 T 12-10-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal VAPA_2c10610 15b79743cc7647ba6eb59a65b28d467a 629 Gene3D G3DSA:3.10.310.70 85 195 1.8E-89 T 12-10-2018 VAPA_2c10610 15b79743cc7647ba6eb59a65b28d467a 629 Gene3D G3DSA:2.30.40.10 13 513 1.8E-89 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 VAPA_2c10610 15b79743cc7647ba6eb59a65b28d467a 629 Gene3D G3DSA:3.20.20.140 66 497 1.8E-89 T 12-10-2018 VAPA_2c10610 15b79743cc7647ba6eb59a65b28d467a 629 SUPERFAMILY SSF51556 65 497 3.27E-42 T 12-10-2018 IPR032466 Metal-dependent hydrolase VAPA_2c10610 15b79743cc7647ba6eb59a65b28d467a 629 SUPERFAMILY SSF51338 3 544 1.3E-23 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 VAPA_2c10610 15b79743cc7647ba6eb59a65b28d467a 629 Pfam PF07969 Amidohydrolase family 54 538 3.5E-121 T 12-10-2018 IPR013108 Amidohydrolase 3 VAPA_2c05040 aaee02c22e705fdb1a255e83b1f4f914 252 SUPERFAMILY SSF46785 142 202 2.37E-9 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_2c05040 aaee02c22e705fdb1a255e83b1f4f914 252 SMART SM00100 6 120 2.4E-6 T 12-10-2018 IPR000595 Cyclic nucleotide-binding domain VAPA_2c05040 aaee02c22e705fdb1a255e83b1f4f914 252 Gene3D G3DSA:1.10.10.10 145 203 1.3E-10 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_2c05040 aaee02c22e705fdb1a255e83b1f4f914 252 Gene3D G3DSA:2.60.120.10 3 144 5.2E-15 T 12-10-2018 IPR014710 RmlC-like jelly roll fold VAPA_2c05040 aaee02c22e705fdb1a255e83b1f4f914 252 SMART SM00419 156 204 3.6E-7 T 12-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 VAPA_2c05040 aaee02c22e705fdb1a255e83b1f4f914 252 SUPERFAMILY SSF51206 11 131 1.83E-15 T 12-10-2018 IPR018490 Cyclic nucleotide-binding-like VAPA_2c05040 aaee02c22e705fdb1a255e83b1f4f914 252 Pfam PF00027 Cyclic nucleotide-binding domain 25 106 1.4E-7 T 12-10-2018 IPR000595 Cyclic nucleotide-binding domain VAPA_2c05040 aaee02c22e705fdb1a255e83b1f4f914 252 Pfam PF13545 Crp-like helix-turn-helix domain 144 202 5.7E-10 T 12-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 VAPA_1c25710 2f619b81e7084ea28fedd136c3dc0c04 91 Pfam PF04362 Bacterial Fe(2+) trafficking 1 88 4.5E-43 T 12-10-2018 IPR007457 Fe(II) trafficking protein YggX GO:0005506 VAPA_1c25710 2f619b81e7084ea28fedd136c3dc0c04 91 SUPERFAMILY SSF111148 1 89 1.96E-39 T 12-10-2018 IPR036766 Fe(II) trafficking protein YggX superfamily GO:0005506 VAPA_1c25710 2f619b81e7084ea28fedd136c3dc0c04 91 PIRSF PIRSF029827 1 90 4.1E-40 T 12-10-2018 IPR007457 Fe(II) trafficking protein YggX GO:0005506 VAPA_1c25710 2f619b81e7084ea28fedd136c3dc0c04 91 ProDom PD029191 TRAFFICKING IRON PROBABLE FE2 YGGX FEII 3D-STRUCTURE OXIDATIVE CONTROL DIRECT 1 75 7.0E-35 T 12-10-2018 IPR007457 Fe(II) trafficking protein YggX GO:0005506 VAPA_1c25710 2f619b81e7084ea28fedd136c3dc0c04 91 Hamap MF_00686 Probable Fe(2+)-trafficking protein [yggX]. 1 88 28.477 T 12-10-2018 IPR007457 Fe(II) trafficking protein YggX GO:0005506 VAPA_1c25710 2f619b81e7084ea28fedd136c3dc0c04 91 Gene3D G3DSA:1.10.3880.10 1 90 4.9E-41 T 12-10-2018 IPR036766 Fe(II) trafficking protein YggX superfamily GO:0005506 VAPA_1c50930 4739afb314370fa207d7321d2c01f086 93 Pfam PF00276 Ribosomal protein L23 3 87 1.8E-28 T 12-10-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 VAPA_1c50930 4739afb314370fa207d7321d2c01f086 93 SUPERFAMILY SSF54189 2 85 9.71E-28 T 12-10-2018 IPR012678 Ribosomal protein L23/L15e core domain superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 VAPA_1c50930 4739afb314370fa207d7321d2c01f086 93 Hamap MF_01369_B 50S ribosomal protein L23 [rplW]. 1 91 21.425 T 12-10-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 VAPA_1c50930 4739afb314370fa207d7321d2c01f086 93 Gene3D G3DSA:3.30.70.330 1 92 9.8E-31 T 12-10-2018 IPR012677 Nucleotide-binding alpha-beta plait domain superfamily VAPA_1c50930 4739afb314370fa207d7321d2c01f086 93 ProSitePatterns PS00050 Ribosomal protein L23 signature. 74 89 - T 12-10-2018 IPR001014 Ribosomal protein L23/L25, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VAPA_1c24270 7967c7193a39b26b2c502dddb66e4983 293 Pfam PF00561 alpha/beta hydrolase fold 22 258 8.9E-16 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 VAPA_1c24270 7967c7193a39b26b2c502dddb66e4983 293 Gene3D G3DSA:3.40.50.1820 2 277 2.0E-53 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c24270 7967c7193a39b26b2c502dddb66e4983 293 SUPERFAMILY SSF53474 2 272 1.58E-55 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c26700 2bb08d0ab76e838288ed54e06fec08e0 145 SUPERFAMILY SSF46785 6 134 1.98E-12 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c26700 2bb08d0ab76e838288ed54e06fec08e0 145 SMART SM00347 26 127 0.0021 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 VAPA_1c26700 2bb08d0ab76e838288ed54e06fec08e0 145 Gene3D G3DSA:1.10.10.10 1 139 1.3E-14 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_2c03970 6e008b89ec95a7478ef3ede304adcc03 929 Pfam PF00005 ABC transporter 302 445 8.2E-26 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_2c03970 6e008b89ec95a7478ef3ede304adcc03 929 Pfam PF00005 ABC transporter 32 179 1.6E-26 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_2c03970 6e008b89ec95a7478ef3ede304adcc03 929 SMART SM00382 41 247 5.3E-7 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_2c03970 6e008b89ec95a7478ef3ede304adcc03 929 SMART SM00382 310 501 2.8E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_2c03970 6e008b89ec95a7478ef3ede304adcc03 929 Gene3D G3DSA:3.40.50.300 18 264 7.7E-55 T 12-10-2018 VAPA_2c03970 6e008b89ec95a7478ef3ede304adcc03 929 Pfam PF12698 ABC-2 family transporter protein 586 921 1.9E-37 T 12-10-2018 VAPA_2c03970 6e008b89ec95a7478ef3ede304adcc03 929 ProSitePatterns PS00211 ABC transporters family signature. 152 166 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_2c03970 6e008b89ec95a7478ef3ede304adcc03 929 SUPERFAMILY SSF52540 19 247 4.79E-50 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_2c03970 6e008b89ec95a7478ef3ede304adcc03 929 SUPERFAMILY SSF52540 285 506 1.7E-62 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_2c03970 6e008b89ec95a7478ef3ede304adcc03 929 Gene3D G3DSA:3.40.50.300 278 525 2.8E-63 T 12-10-2018 VAPA_1c22410 221d6c35280429e7a888270170a14129 199 SUPERFAMILY SSF52499 2 194 3.66E-41 T 12-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 VAPA_1c22410 221d6c35280429e7a888270170a14129 199 Pfam PF00857 Isochorismatase family 4 187 4.7E-35 T 12-10-2018 IPR000868 Isochorismatase-like GO:0003824 VAPA_1c22410 221d6c35280429e7a888270170a14129 199 Gene3D G3DSA:3.40.50.850 1 196 2.1E-43 T 12-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 VAPA_1c16560 51b8c8d9613806d6ae7e56f3b3b2a4ad 646 Pfam PF11737 Protein of unknown function (DUF3300) 64 320 1.5E-62 T 12-10-2018 IPR021728 Protein of unknown function DUF3300 VAPA_1c08530 1ff3417594e96b7296f01d355cfb90b2 401 Gene3D G3DSA:3.40.50.2300 152 288 2.9E-70 T 12-10-2018 VAPA_1c08530 1ff3417594e96b7296f01d355cfb90b2 401 Gene3D G3DSA:3.40.50.2300 32 352 2.9E-70 T 12-10-2018 VAPA_1c08530 1ff3417594e96b7296f01d355cfb90b2 401 Pfam PF13458 Periplasmic binding protein 30 378 1.3E-50 T 12-10-2018 IPR028081 Leucine-binding protein domain VAPA_1c08530 1ff3417594e96b7296f01d355cfb90b2 401 SUPERFAMILY SSF53822 30 398 5.05E-68 T 12-10-2018 IPR028082 Periplasmic binding protein-like I VAPA_1c08530 1ff3417594e96b7296f01d355cfb90b2 401 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 31 47 1.3E-6 T 12-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 VAPA_1c08530 1ff3417594e96b7296f01d355cfb90b2 401 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 53 69 1.3E-6 T 12-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 VAPA_1c36680 a5b9d358050abb394d39b69b1639edc1 218 Gene3D G3DSA:1.10.60.30 125 202 5.1E-22 T 12-10-2018 VAPA_1c36680 a5b9d358050abb394d39b69b1639edc1 218 Gene3D G3DSA:1.10.60.30 46 119 2.4E-21 T 12-10-2018 VAPA_1c36680 a5b9d358050abb394d39b69b1639edc1 218 Pfam PF04751 Protein of unknown function (DUF615) 35 194 1.3E-50 T 12-10-2018 IPR006839 Ribosome-associated, YjgA VAPA_1c36680 a5b9d358050abb394d39b69b1639edc1 218 SUPERFAMILY SSF158710 46 197 2.09E-43 T 12-10-2018 IPR023153 PSPTO4464-like domain superfamily VAPA_1c36680 a5b9d358050abb394d39b69b1639edc1 218 PIRSF PIRSF016183 22 201 4.8E-51 T 12-10-2018 IPR006839 Ribosome-associated, YjgA VAPA_1c02270 04c24bad19af5e615a10e6cbcb2deb4f 362 TIGRFAM TIGR03363 VI_chp_8: type VI secretion-associated protein, ImpA family 5 352 1.8E-75 T 12-10-2018 IPR017740 Type VI secretion system-associated, ImpA VAPA_1c02270 04c24bad19af5e615a10e6cbcb2deb4f 362 Pfam PF06812 ImpA, N-terminal, type VI secretion system 12 133 5.7E-34 T 12-10-2018 IPR010657 ImpA, N-terminal VAPA_2c09630 506982627112017aa545c29b75a23603 330 Gene3D G3DSA:3.40.190.10 133 255 1.5E-100 T 12-10-2018 VAPA_2c09630 506982627112017aa545c29b75a23603 330 PIRSF PIRSF017082 7 330 6.5E-65 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_2c09630 506982627112017aa545c29b75a23603 330 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 55 326 3.2E-74 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_2c09630 506982627112017aa545c29b75a23603 330 Gene3D G3DSA:3.40.190.150 36 320 1.5E-100 T 12-10-2018 VAPA_2c09630 506982627112017aa545c29b75a23603 330 SUPERFAMILY SSF53850 101 284 8.69E-6 T 12-10-2018 VAPA_2c03860 505df5e641919918faa97b16175721e4 862 Gene3D G3DSA:3.40.50.1000 500 636 9.1E-70 T 12-10-2018 IPR023214 HAD superfamily VAPA_2c03860 505df5e641919918faa97b16175721e4 862 Gene3D G3DSA:2.70.150.10 25 231 9.5E-63 T 12-10-2018 VAPA_2c03860 505df5e641919918faa97b16175721e4 862 Pfam PF00122 E1-E2 ATPase 121 307 2.1E-46 T 12-10-2018 VAPA_2c03860 505df5e641919918faa97b16175721e4 862 Gene3D G3DSA:1.20.1110.10 44 325 9.5E-63 T 12-10-2018 VAPA_2c03860 505df5e641919918faa97b16175721e4 862 Gene3D G3DSA:1.20.1110.10 637 772 9.1E-70 T 12-10-2018 VAPA_2c03860 505df5e641919918faa97b16175721e4 862 TIGRFAM TIGR01524 ATPase-IIIB_Mg: magnesium-translocating P-type ATPase 27 842 1.5E-258 T 12-10-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 VAPA_2c03860 505df5e641919918faa97b16175721e4 862 SMART SM00831 16 82 4.6E-8 T 12-10-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 VAPA_2c03860 505df5e641919918faa97b16175721e4 862 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 331 337 - T 12-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 VAPA_2c03860 505df5e641919918faa97b16175721e4 862 Pfam PF00702 haloacid dehalogenase-like hydrolase 325 606 1.0E-12 T 12-10-2018 VAPA_2c03860 505df5e641919918faa97b16175721e4 862 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 89 350 3.4E-36 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 VAPA_2c03860 505df5e641919918faa97b16175721e4 862 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 564 682 6.4E-26 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 VAPA_2c03860 505df5e641919918faa97b16175721e4 862 SUPERFAMILY SSF56784 327 692 2.12E-37 T 12-10-2018 IPR036412 HAD-like superfamily VAPA_2c03860 505df5e641919918faa97b16175721e4 862 Pfam PF00690 Cation transporter/ATPase, N-terminus 28 77 2.5E-8 T 12-10-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 VAPA_2c03860 505df5e641919918faa97b16175721e4 862 Gene3D G3DSA:3.40.50.1000 326 338 9.5E-63 T 12-10-2018 IPR023214 HAD superfamily VAPA_2c03860 505df5e641919918faa97b16175721e4 862 SUPERFAMILY SSF81665 22 842 8.11E-91 T 12-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 VAPA_2c03860 505df5e641919918faa97b16175721e4 862 Pfam PF00689 Cation transporting ATPase, C-terminus 675 838 1.3E-11 T 12-10-2018 IPR006068 Cation-transporting P-type ATPase, C-terminal Reactome: R-HSA-936837 VAPA_2c03860 505df5e641919918faa97b16175721e4 862 PRINTS PR01836 Magnesium-transporting ATPase signature 259 278 6.6E-40 T 12-10-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 VAPA_2c03860 505df5e641919918faa97b16175721e4 862 PRINTS PR01836 Magnesium-transporting ATPase signature 751 772 6.6E-40 T 12-10-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 VAPA_2c03860 505df5e641919918faa97b16175721e4 862 PRINTS PR01836 Magnesium-transporting ATPase signature 668 679 6.6E-40 T 12-10-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 VAPA_2c03860 505df5e641919918faa97b16175721e4 862 PRINTS PR01836 Magnesium-transporting ATPase signature 242 258 6.6E-40 T 12-10-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 VAPA_2c03860 505df5e641919918faa97b16175721e4 862 PRINTS PR01836 Magnesium-transporting ATPase signature 700 713 6.6E-40 T 12-10-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 VAPA_2c03860 505df5e641919918faa97b16175721e4 862 PRINTS PR01836 Magnesium-transporting ATPase signature 363 376 6.6E-40 T 12-10-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 VAPA_2c03860 505df5e641919918faa97b16175721e4 862 PRINTS PR01836 Magnesium-transporting ATPase signature 650 665 6.6E-40 T 12-10-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 VAPA_2c03860 505df5e641919918faa97b16175721e4 862 PRINTS PR01836 Magnesium-transporting ATPase signature 720 736 6.6E-40 T 12-10-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 VAPA_2c03860 505df5e641919918faa97b16175721e4 862 PRINTS PR01836 Magnesium-transporting ATPase signature 800 821 6.6E-40 T 12-10-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 VAPA_2c03860 505df5e641919918faa97b16175721e4 862 SUPERFAMILY SSF81653 121 229 6.93E-30 T 12-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 VAPA_2c03860 505df5e641919918faa97b16175721e4 862 Gene3D G3DSA:3.40.1110.10 384 499 9.1E-70 T 12-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 VAPA_1c11720 6b9fe2b9ba3bb5b84ba12482713323e2 312 SUPERFAMILY SSF46689 205 255 6.72E-9 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 VAPA_1c11720 6b9fe2b9ba3bb5b84ba12482713323e2 312 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 258 300 - T 12-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 VAPA_1c11720 6b9fe2b9ba3bb5b84ba12482713323e2 312 SUPERFAMILY SSF46689 257 306 1.08E-13 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 VAPA_1c11720 6b9fe2b9ba3bb5b84ba12482713323e2 312 Gene3D G3DSA:1.10.10.60 204 253 3.4E-13 T 12-10-2018 VAPA_1c11720 6b9fe2b9ba3bb5b84ba12482713323e2 312 SUPERFAMILY SSF51215 46 96 6.15E-7 T 12-10-2018 IPR037923 Transcription regulator HTH-like VAPA_1c11720 6b9fe2b9ba3bb5b84ba12482713323e2 312 SMART SM00342 221 304 8.6E-31 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 VAPA_1c11720 6b9fe2b9ba3bb5b84ba12482713323e2 312 Gene3D G3DSA:1.10.10.60 254 309 3.7E-18 T 12-10-2018 VAPA_1c11720 6b9fe2b9ba3bb5b84ba12482713323e2 312 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 273 288 5.6E-5 T 12-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 VAPA_1c11720 6b9fe2b9ba3bb5b84ba12482713323e2 312 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 288 304 5.6E-5 T 12-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 VAPA_1c11720 6b9fe2b9ba3bb5b84ba12482713323e2 312 Pfam PF12833 Helix-turn-helix domain 227 306 1.1E-23 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 VAPA_1c49010 c7e499beb757eaa3a48e9dd9432a3b2f 273 Pfam PF01569 PAP2 superfamily 145 261 1.7E-15 T 12-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase VAPA_1c49010 c7e499beb757eaa3a48e9dd9432a3b2f 273 SMART SM00014 141 257 5.4E-12 T 12-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase VAPA_1c49010 c7e499beb757eaa3a48e9dd9432a3b2f 273 Gene3D G3DSA:1.20.144.10 89 175 4.8E-6 T 12-10-2018 VAPA_1c49010 c7e499beb757eaa3a48e9dd9432a3b2f 273 Gene3D G3DSA:1.20.144.10 176 272 3.3E-18 T 12-10-2018 VAPA_1c49010 c7e499beb757eaa3a48e9dd9432a3b2f 273 SUPERFAMILY SSF48317 58 269 6.41E-32 T 12-10-2018 IPR036938 Phosphatidic acid phosphatase type 2/haloperoxidase superfamily VAPA_1c54450 c1cd962285b1ff07f7304d4b3c3fb2bd 522 Gene3D G3DSA:3.10.105.10 281 490 2.8E-55 T 12-10-2018 VAPA_1c54450 c1cd962285b1ff07f7304d4b3c3fb2bd 522 PIRSF PIRSF002741 5 522 4.8E-130 T 12-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 VAPA_1c54450 c1cd962285b1ff07f7304d4b3c3fb2bd 522 SUPERFAMILY SSF53850 30 514 4.19E-133 T 12-10-2018 VAPA_1c54450 c1cd962285b1ff07f7304d4b3c3fb2bd 522 Gene3D G3DSA:3.40.190.10 26 271 9.9E-71 T 12-10-2018 VAPA_1c54450 c1cd962285b1ff07f7304d4b3c3fb2bd 522 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 79 435 9.1E-85 T 12-10-2018 IPR000914 Solute-binding protein family 5 domain VAPA_1c54650 a4027a0b68ef7ed011b71e9a985c9de1 102 SUPERFAMILY SSF54909 1 99 5.03E-27 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel VAPA_1c54650 a4027a0b68ef7ed011b71e9a985c9de1 102 Pfam PF03992 Antibiotic biosynthesis monooxygenase 1 82 2.5E-18 T 12-10-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain VAPA_1c54650 a4027a0b68ef7ed011b71e9a985c9de1 102 Gene3D G3DSA:3.30.70.100 1 102 8.6E-28 T 12-10-2018 VAPA_1c09040 398030bac0f612a80a60a2ce5eed1b34 396 ProSitePatterns PS00737 Thiolases signature 2. 342 358 - T 12-10-2018 IPR020613 Thiolase, conserved site GO:0016747 VAPA_1c09040 398030bac0f612a80a60a2ce5eed1b34 396 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 394 2.4E-118 T 12-10-2018 IPR002155 Thiolase GO:0016747 VAPA_1c09040 398030bac0f612a80a60a2ce5eed1b34 396 Pfam PF00108 Thiolase, N-terminal domain 5 265 4.1E-55 T 12-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 VAPA_1c09040 398030bac0f612a80a60a2ce5eed1b34 396 SUPERFAMILY SSF53901 274 395 1.09E-39 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 VAPA_1c09040 398030bac0f612a80a60a2ce5eed1b34 396 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 86 104 - T 12-10-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0016747 VAPA_1c09040 398030bac0f612a80a60a2ce5eed1b34 396 Gene3D G3DSA:3.40.47.10 4 279 5.4E-130 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 VAPA_1c09040 398030bac0f612a80a60a2ce5eed1b34 396 ProSitePatterns PS00099 Thiolases active site. 377 390 - T 12-10-2018 IPR020610 Thiolase, active site GO:0016747 VAPA_1c09040 398030bac0f612a80a60a2ce5eed1b34 396 Pfam PF02803 Thiolase, C-terminal domain 273 394 1.9E-43 T 12-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 VAPA_1c09040 398030bac0f612a80a60a2ce5eed1b34 396 PIRSF PIRSF000429 1 396 7.0E-112 T 12-10-2018 IPR002155 Thiolase GO:0016747 VAPA_1c09040 398030bac0f612a80a60a2ce5eed1b34 396 SUPERFAMILY SSF53901 1 269 2.37E-64 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 VAPA_1c09040 398030bac0f612a80a60a2ce5eed1b34 396 Gene3D G3DSA:3.40.47.10 126 388 5.4E-130 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 VAPA_1c22060 50f249ee65b3c7bc782ec9de94e18744 418 Pfam PF12867 DinB superfamily 31 173 1.8E-5 T 12-10-2018 IPR024775 DinB-like domain VAPA_1c22060 50f249ee65b3c7bc782ec9de94e18744 418 SUPERFAMILY SSF56436 205 411 7.53E-48 T 12-10-2018 IPR016187 C-type lectin fold VAPA_1c22060 50f249ee65b3c7bc782ec9de94e18744 418 TIGRFAM TIGR04373 egtB_X_signatur: EgtB-related enzyme signature domain 365 412 3.3E-26 T 12-10-2018 IPR030809 EgtB-related enzyme signature domain VAPA_1c22060 50f249ee65b3c7bc782ec9de94e18744 418 Pfam PF03781 Sulfatase-modifying factor enzyme 1 344 411 5.7E-6 T 12-10-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 VAPA_1c22060 50f249ee65b3c7bc782ec9de94e18744 418 Pfam PF03781 Sulfatase-modifying factor enzyme 1 203 335 2.4E-17 T 12-10-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 VAPA_1c22060 50f249ee65b3c7bc782ec9de94e18744 418 Gene3D G3DSA:3.90.1580.10 198 343 1.3E-27 T 12-10-2018 VAPA_1c22060 50f249ee65b3c7bc782ec9de94e18744 418 Gene3D G3DSA:3.90.1580.10 344 416 1.6E-7 T 12-10-2018 VAPA_1c22060 50f249ee65b3c7bc782ec9de94e18744 418 SUPERFAMILY SSF109854 25 180 2.38E-8 T 12-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes VAPA_1c22060 50f249ee65b3c7bc782ec9de94e18744 418 TIGRFAM TIGR03440 egtB_TIGR03440: ergothioneine biosynthesis protein EgtB 29 412 7.1E-93 T 12-10-2018 IPR017806 Ergothioneine biosynthesis protein EgtB GO:0052699 KEGG: 00340+1.14.99.50|MetaCyc: PWY-7255 VAPA_2c06890 0fcb13dcb9a9d795e0de4dac39e17e92 804 SUPERFAMILY SSF53720 524 769 1.44E-46 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 VAPA_2c06890 0fcb13dcb9a9d795e0de4dac39e17e92 804 Gene3D G3DSA:3.40.605.10 524 804 1.6E-50 T 12-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 VAPA_2c06890 0fcb13dcb9a9d795e0de4dac39e17e92 804 PIRSF PIRSF036490 6 804 0.0 T 12-10-2018 IPR011408 Aldehyde dehydrogenase VAPA_2c06890 0fcb13dcb9a9d795e0de4dac39e17e92 804 Pfam PF00171 Aldehyde dehydrogenase family 49 492 5.9E-156 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 VAPA_2c06890 0fcb13dcb9a9d795e0de4dac39e17e92 804 Pfam PF00171 Aldehyde dehydrogenase family 547 771 2.2E-38 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 VAPA_2c06890 0fcb13dcb9a9d795e0de4dac39e17e92 804 Gene3D G3DSA:3.40.309.10 275 464 4.8E-164 T 12-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 VAPA_2c06890 0fcb13dcb9a9d795e0de4dac39e17e92 804 Gene3D G3DSA:3.40.605.10 42 490 4.8E-164 T 12-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 VAPA_2c06890 0fcb13dcb9a9d795e0de4dac39e17e92 804 SUPERFAMILY SSF53720 32 494 2.36E-156 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 VAPA_2c06890 0fcb13dcb9a9d795e0de4dac39e17e92 804 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 270 277 - T 12-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 VAPA_1c24350 e6b37f291f50089de11d7b0339128050 399 Pfam PF13006 Insertion element 4 transposase N-terminal 19 113 8.3E-26 T 12-10-2018 IPR024473 Transposase, IS4, N-terminal VAPA_1c24350 e6b37f291f50089de11d7b0339128050 399 SUPERFAMILY SSF53098 132 392 6.75E-25 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily VAPA_1c24350 e6b37f291f50089de11d7b0339128050 399 Pfam PF01609 Transposase DDE domain 133 357 1.9E-15 T 12-10-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 VAPA_1c11500 e6b37f291f50089de11d7b0339128050 399 Pfam PF13006 Insertion element 4 transposase N-terminal 19 113 8.3E-26 T 12-10-2018 IPR024473 Transposase, IS4, N-terminal VAPA_1c11500 e6b37f291f50089de11d7b0339128050 399 SUPERFAMILY SSF53098 132 392 6.75E-25 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily VAPA_1c11500 e6b37f291f50089de11d7b0339128050 399 Pfam PF01609 Transposase DDE domain 133 357 1.9E-15 T 12-10-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 VAPA_1c10540 dc048096e2e453199efe5efd40812991 256 SUPERFAMILY SSF51206 22 154 5.11E-22 T 12-10-2018 IPR018490 Cyclic nucleotide-binding-like VAPA_1c10540 dc048096e2e453199efe5efd40812991 256 Gene3D G3DSA:1.10.10.10 164 247 9.3E-17 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c10540 dc048096e2e453199efe5efd40812991 256 Pfam PF00027 Cyclic nucleotide-binding domain 49 133 1.2E-10 T 12-10-2018 IPR000595 Cyclic nucleotide-binding domain VAPA_1c10540 dc048096e2e453199efe5efd40812991 256 SUPERFAMILY SSF46785 164 242 4.58E-13 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c10540 dc048096e2e453199efe5efd40812991 256 Pfam PF13545 Crp-like helix-turn-helix domain 167 241 7.2E-13 T 12-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 VAPA_1c10540 dc048096e2e453199efe5efd40812991 256 SMART SM00419 187 235 0.0058 T 12-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 VAPA_1c10540 dc048096e2e453199efe5efd40812991 256 Gene3D G3DSA:2.60.120.10 46 163 2.5E-27 T 12-10-2018 IPR014710 RmlC-like jelly roll fold VAPA_1c38880 d4007620252a7279a213c7c227043c26 406 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 14 401 9.4E-129 T 12-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 VAPA_1c38880 d4007620252a7279a213c7c227043c26 406 Gene3D G3DSA:3.40.640.10 10 261 2.0E-81 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 VAPA_1c38880 d4007620252a7279a213c7c227043c26 406 PIRSF PIRSF001434 3 405 2.5E-126 T 12-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 VAPA_1c38880 d4007620252a7279a213c7c227043c26 406 TIGRFAM TIGR01325 O_suc_HS_sulf: O-succinylhomoserine sulfhydrylase 14 401 2.2E-161 T 12-10-2018 IPR006234 O-succinylhomoserine sulfhydrylase GO:0071268 VAPA_1c38880 d4007620252a7279a213c7c227043c26 406 Gene3D G3DSA:3.90.1150.10 265 406 2.8E-47 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 VAPA_1c38880 d4007620252a7279a213c7c227043c26 406 Hamap MF_02056 O-succinylhomoserine sulfhydrylase [metZ]. 15 402 51.636 T 12-10-2018 IPR006234 O-succinylhomoserine sulfhydrylase GO:0071268 VAPA_1c38880 d4007620252a7279a213c7c227043c26 406 SUPERFAMILY SSF53383 36 402 1.88E-110 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase VAPA_1c38880 d4007620252a7279a213c7c227043c26 406 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 205 219 - T 12-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 VAPA_1c22910 70eac1b6ad340a53996f69e3bfe9998d 333 SUPERFAMILY SSF51395 15 310 1.51E-68 T 12-10-2018 VAPA_1c22910 70eac1b6ad340a53996f69e3bfe9998d 333 Hamap MF_02041 tRNA-dihydrouridine(20/20a) synthase [dusA]. 6 331 50.339 T 12-10-2018 IPR004653 tRNA-dihydrouridine(20/20a) synthase GO:0002943|GO:0017150 VAPA_1c22910 70eac1b6ad340a53996f69e3bfe9998d 333 Gene3D G3DSA:3.20.20.70 11 253 8.3E-73 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 VAPA_1c22910 70eac1b6ad340a53996f69e3bfe9998d 333 TIGRFAM TIGR00742 yjbN: tRNA dihydrouridine synthase A 15 325 3.1E-135 T 12-10-2018 IPR004653 tRNA-dihydrouridine(20/20a) synthase GO:0002943|GO:0017150 VAPA_1c22910 70eac1b6ad340a53996f69e3bfe9998d 333 Pfam PF01207 Dihydrouridine synthase (Dus) 17 317 7.2E-82 T 12-10-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 VAPA_1c22910 70eac1b6ad340a53996f69e3bfe9998d 333 Gene3D G3DSA:1.20.120.1460 256 329 7.6E-13 T 12-10-2018 VAPA_1c22910 70eac1b6ad340a53996f69e3bfe9998d 333 ProSitePatterns PS01136 Uncharacterized protein family UPF0034 signature. 96 114 - T 12-10-2018 IPR018517 tRNA-dihydrouridine synthase, conserved site GO:0008033|GO:0017150|GO:0050660|GO:0055114 VAPA_1c22910 70eac1b6ad340a53996f69e3bfe9998d 333 PIRSF PIRSF006621 4 330 4.7E-76 T 12-10-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 VAPA_1c13920 c40cc874fcaf77fe21b9248c17ef60f1 416 Gene3D G3DSA:3.90.15.10 138 262 2.3E-78 T 12-10-2018 IPR014711 DNA topoisomerase I, catalytic core, alpha-helical subdomain, eukaryotic-type GO:0003677|GO:0003917|GO:0006265 VAPA_1c13920 c40cc874fcaf77fe21b9248c17ef60f1 416 Gene3D G3DSA:3.30.66.10 33 113 3.0E-31 T 12-10-2018 IPR035447 DNA topoisomerase I, N-terminal VAPA_1c13920 c40cc874fcaf77fe21b9248c17ef60f1 416 Pfam PF01028 Eukaryotic DNA topoisomerase I, catalytic core 108 318 6.4E-27 T 12-10-2018 IPR013500 DNA topoisomerase I, catalytic core, eukaryotic-type GO:0003677|GO:0003917|GO:0006265 VAPA_1c13920 c40cc874fcaf77fe21b9248c17ef60f1 416 SUPERFAMILY SSF56349 103 328 1.32E-58 T 12-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 VAPA_1c13920 c40cc874fcaf77fe21b9248c17ef60f1 416 SUPERFAMILY SSF55869 47 108 2.09E-21 T 12-10-2018 IPR035447 DNA topoisomerase I, N-terminal VAPA_1c13920 c40cc874fcaf77fe21b9248c17ef60f1 416 PRINTS PR00416 Eukaryotic DNA topoisomerase I signature 151 170 8.2E-8 T 12-10-2018 IPR001631 DNA topoisomerase I GO:0003677|GO:0003917|GO:0006265 VAPA_1c13920 c40cc874fcaf77fe21b9248c17ef60f1 416 PRINTS PR00416 Eukaryotic DNA topoisomerase I signature 195 211 8.2E-8 T 12-10-2018 IPR001631 DNA topoisomerase I GO:0003677|GO:0003917|GO:0006265 VAPA_1c13920 c40cc874fcaf77fe21b9248c17ef60f1 416 PRINTS PR00416 Eukaryotic DNA topoisomerase I signature 174 188 8.2E-8 T 12-10-2018 IPR001631 DNA topoisomerase I GO:0003677|GO:0003917|GO:0006265 VAPA_1c13920 c40cc874fcaf77fe21b9248c17ef60f1 416 PRINTS PR00416 Eukaryotic DNA topoisomerase I signature 314 325 8.2E-8 T 12-10-2018 IPR001631 DNA topoisomerase I GO:0003677|GO:0003917|GO:0006265 VAPA_1c13920 c40cc874fcaf77fe21b9248c17ef60f1 416 PRINTS PR00416 Eukaryotic DNA topoisomerase I signature 261 275 8.2E-8 T 12-10-2018 IPR001631 DNA topoisomerase I GO:0003677|GO:0003917|GO:0006265 VAPA_1c13920 c40cc874fcaf77fe21b9248c17ef60f1 416 Gene3D G3DSA:1.10.132.120 115 330 2.3E-78 T 12-10-2018 VAPA_1c41480 97703a596d2b25bc6d082a3cd462af4d 336 Pfam PF00248 Aldo/keto reductase family 18 325 1.8E-67 T 12-10-2018 IPR023210 NADP-dependent oxidoreductase domain VAPA_1c41480 97703a596d2b25bc6d082a3cd462af4d 336 SUPERFAMILY SSF51430 4 330 7.6E-96 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily VAPA_1c41480 97703a596d2b25bc6d082a3cd462af4d 336 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 147 164 - T 12-10-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 VAPA_1c41480 97703a596d2b25bc6d082a3cd462af4d 336 Gene3D G3DSA:3.20.20.100 3 334 2.3E-110 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily VAPA_1c03630 bf8760d6c08a4e98ff0071e069ad3cb6 273 SUPERFAMILY SSF52540 9 246 2.33E-60 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c03630 bf8760d6c08a4e98ff0071e069ad3cb6 273 Pfam PF00005 ABC transporter 30 174 1.5E-27 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c03630 bf8760d6c08a4e98ff0071e069ad3cb6 273 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_1c03630 bf8760d6c08a4e98ff0071e069ad3cb6 273 SMART SM00382 37 230 7.7E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c03630 bf8760d6c08a4e98ff0071e069ad3cb6 273 Gene3D G3DSA:3.40.50.300 6 269 9.4E-67 T 12-10-2018 VAPA_1c10690 97b979e5e716a187b4ca8116f2740d02 301 Gene3D G3DSA:3.20.20.370 2 301 1.2E-98 T 12-10-2018 VAPA_1c10690 97b979e5e716a187b4ca8116f2740d02 301 Pfam PF01522 Polysaccharide deacetylase 75 182 1.8E-16 T 12-10-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 VAPA_1c10690 97b979e5e716a187b4ca8116f2740d02 301 SUPERFAMILY SSF88713 6 298 3.46E-87 T 12-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 VAPA_1c01230 8977307efe96b5e322cfe52f05b965e0 475 Gene3D G3DSA:3.20.20.140 58 433 7.8E-173 T 12-10-2018 VAPA_1c01230 8977307efe96b5e322cfe52f05b965e0 475 SUPERFAMILY SSF51556 58 393 2.69E-103 T 12-10-2018 IPR032466 Metal-dependent hydrolase VAPA_1c01230 8977307efe96b5e322cfe52f05b965e0 475 TIGRFAM TIGR02033 D-hydantoinase: dihydropyrimidinase 10 464 7.4E-159 T 12-10-2018 IPR011778 Hydantoinase/dihydropyrimidinase GO:0005737 Reactome: R-HSA-399956 VAPA_1c01230 8977307efe96b5e322cfe52f05b965e0 475 Pfam PF01979 Amidohydrolase family 55 446 1.7E-27 T 12-10-2018 IPR006680 Amidohydrolase-related GO:0016787 VAPA_1c01230 8977307efe96b5e322cfe52f05b965e0 475 SUPERFAMILY SSF51338 360 463 2.97E-30 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 VAPA_1c01230 8977307efe96b5e322cfe52f05b965e0 475 SUPERFAMILY SSF51338 7 71 6.17E-13 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 VAPA_1c01230 8977307efe96b5e322cfe52f05b965e0 475 Gene3D G3DSA:2.30.40.10 8 462 7.8E-173 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 VAPA_1c12740 fb5e06866bb11ec8704b712dd10d7c1c 524 SUPERFAMILY SSF53850 46 523 3.71E-97 T 12-10-2018 VAPA_1c12740 fb5e06866bb11ec8704b712dd10d7c1c 524 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 86 434 1.7E-64 T 12-10-2018 IPR000914 Solute-binding protein family 5 domain VAPA_1c12740 fb5e06866bb11ec8704b712dd10d7c1c 524 Gene3D G3DSA:3.40.190.10 198 508 4.4E-85 T 12-10-2018 VAPA_1c12740 fb5e06866bb11ec8704b712dd10d7c1c 524 PIRSF PIRSF002741 10 514 9.3E-64 T 12-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 VAPA_1c12740 fb5e06866bb11ec8704b712dd10d7c1c 524 Gene3D G3DSA:3.10.105.10 285 500 4.4E-85 T 12-10-2018 VAPA_1c12740 fb5e06866bb11ec8704b712dd10d7c1c 524 Gene3D G3DSA:3.90.76.10 52 197 4.4E-85 T 12-10-2018 VAPA_1c14230 aded4ae210fa252dc351f3033e619fd8 315 Gene3D G3DSA:1.10.3720.10 99 312 3.4E-23 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c14230 aded4ae210fa252dc351f3033e619fd8 315 SUPERFAMILY SSF161098 104 292 1.7E-27 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c14230 aded4ae210fa252dc351f3033e619fd8 315 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 126 311 4.6E-25 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 VAPA_1c19230 0173ab94ecfc11064b5301a663229115 330 Gene3D G3DSA:3.40.190.10 131 255 5.6E-84 T 12-10-2018 VAPA_1c19230 0173ab94ecfc11064b5301a663229115 330 Gene3D G3DSA:3.40.190.150 36 320 5.6E-84 T 12-10-2018 VAPA_1c19230 0173ab94ecfc11064b5301a663229115 330 PIRSF PIRSF017082 3 329 3.4E-59 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c19230 0173ab94ecfc11064b5301a663229115 330 SUPERFAMILY SSF53850 118 289 1.33E-6 T 12-10-2018 VAPA_1c19230 0173ab94ecfc11064b5301a663229115 330 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 52 326 1.7E-53 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c55130 084a0b67b61e4f2b8c71af5c2047995f 44 ProDom PD003101 RIBOSOMAL L34 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID L34 MITOCHONDRIAL PEPTIDE SEQUENCING 1 42 1.0E-13 T 12-10-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 VAPA_1c55130 084a0b67b61e4f2b8c71af5c2047995f 44 ProSitePatterns PS00784 Ribosomal protein L34 signature. 2 21 - T 12-10-2018 IPR020939 Ribosomal protein L34, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 VAPA_1c55130 084a0b67b61e4f2b8c71af5c2047995f 44 TIGRFAM TIGR01030 rpmH_bact: ribosomal protein bL34 1 44 7.2E-23 T 12-10-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 VAPA_1c55130 084a0b67b61e4f2b8c71af5c2047995f 44 Pfam PF00468 Ribosomal protein L34 1 44 6.4E-22 T 12-10-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 VAPA_1c55130 084a0b67b61e4f2b8c71af5c2047995f 44 Hamap MF_00391 50S ribosomal protein L34 [rpmH]. 1 44 15.098 T 12-10-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 VAPA_1c04210 52e5a6fa739ba14b7faab7849ede4299 427 SUPERFAMILY SSF51905 11 369 6.24E-53 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c04210 52e5a6fa739ba14b7faab7849ede4299 427 Gene3D G3DSA:3.30.9.30 44 366 3.7E-110 T 12-10-2018 VAPA_1c04210 52e5a6fa739ba14b7faab7849ede4299 427 SUPERFAMILY SSF54373 187 286 5.69E-13 T 12-10-2018 VAPA_1c04210 52e5a6fa739ba14b7faab7849ede4299 427 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 308 324 1.2E-17 T 12-10-2018 VAPA_1c04210 52e5a6fa739ba14b7faab7849ede4299 427 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 342 358 1.2E-17 T 12-10-2018 VAPA_1c04210 52e5a6fa739ba14b7faab7849ede4299 427 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 293 308 1.2E-17 T 12-10-2018 VAPA_1c04210 52e5a6fa739ba14b7faab7849ede4299 427 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 162 177 1.2E-17 T 12-10-2018 VAPA_1c04210 52e5a6fa739ba14b7faab7849ede4299 427 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 11 33 1.2E-17 T 12-10-2018 VAPA_1c04210 52e5a6fa739ba14b7faab7849ede4299 427 Pfam PF01494 FAD binding domain 11 330 1.6E-24 T 12-10-2018 IPR002938 FAD-binding domain GO:0071949 VAPA_1c04210 52e5a6fa739ba14b7faab7849ede4299 427 Gene3D G3DSA:3.50.50.60 12 358 3.7E-110 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c13520 eae08d773a62eac7686323f06f896d4f 800 Gene3D G3DSA:1.10.10.10 729 794 4.2E-28 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c13520 eae08d773a62eac7686323f06f896d4f 800 SUPERFAMILY SSF46785 733 797 1.43E-21 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c13520 eae08d773a62eac7686323f06f896d4f 800 Pfam PF13491 4TM region of DNA translocase FtsK/SpoIIIE 25 209 9.0E-49 T 12-10-2018 IPR025199 DNA translocase FtsK, 4TM region VAPA_1c13520 eae08d773a62eac7686323f06f896d4f 800 SMART SM00382 456 651 0.0066 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c13520 eae08d773a62eac7686323f06f896d4f 800 Pfam PF09397 Ftsk gamma domain 735 795 2.4E-27 T 12-10-2018 IPR018541 FtsK gamma domain VAPA_1c13520 eae08d773a62eac7686323f06f896d4f 800 SMART SM00843 733 798 1.2E-37 T 12-10-2018 IPR018541 FtsK gamma domain VAPA_1c13520 eae08d773a62eac7686323f06f896d4f 800 Gene3D G3DSA:3.40.50.300 418 716 7.5E-113 T 12-10-2018 VAPA_1c13520 eae08d773a62eac7686323f06f896d4f 800 SUPERFAMILY SSF52540 436 702 6.37E-48 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c13520 eae08d773a62eac7686323f06f896d4f 800 Gene3D G3DSA:3.30.980.40 313 417 6.2E-32 T 12-10-2018 VAPA_1c13520 eae08d773a62eac7686323f06f896d4f 800 Pfam PF01580 FtsK/SpoIIIE family 421 630 1.7E-63 T 12-10-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 VAPA_1c18130 04bbc39662ad0bc7dcb48b557ec25211 330 PIRSF PIRSF006470 1 330 3.0E-99 T 12-10-2018 IPR004682 TRAP transporter solute receptor, DctP family GO:0030288|GO:0055085 VAPA_1c18130 04bbc39662ad0bc7dcb48b557ec25211 330 Gene3D G3DSA:3.40.190.170 31 330 1.6E-119 T 12-10-2018 IPR038404 TRAP transporter solute receptor DctP superfamily VAPA_1c18130 04bbc39662ad0bc7dcb48b557ec25211 330 TIGRFAM TIGR00787 dctP: TRAP transporter solute receptor, DctP family 41 291 2.4E-62 T 12-10-2018 IPR004682 TRAP transporter solute receptor, DctP family GO:0030288|GO:0055085 VAPA_1c18130 04bbc39662ad0bc7dcb48b557ec25211 330 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 36 314 1.7E-77 T 12-10-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0030288|GO:0055085 VAPA_1c44090 69e8d48735c9855e5c7e0d67e4d42b06 207 SUPERFAMILY SSF55874 42 198 3.34E-6 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_2c11050 ea8f883cb1d0432edb5b1fe4d2242598 439 Gene3D G3DSA:1.10.4100.10 8 398 1.7E-78 T 12-10-2018 VAPA_2c11050 ea8f883cb1d0432edb5b1fe4d2242598 439 Gene3D G3DSA:3.30.1330.120 251 382 1.7E-78 T 12-10-2018 VAPA_2c11050 ea8f883cb1d0432edb5b1fe4d2242598 439 SUPERFAMILY SSF103378 3 422 4.97E-84 T 12-10-2018 IPR036148 MmgE/PrpD superfamily GO:0016829 VAPA_2c11050 ea8f883cb1d0432edb5b1fe4d2242598 439 Pfam PF03972 MmgE/PrpD family 4 409 4.2E-89 T 12-10-2018 IPR005656 MmgE/PrpD GO:0016829 VAPA_1c48270 8270d7f89df2bdd78e2b259c2a8dd291 476 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 18 430 3.9E-71 T 12-10-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0016021|GO:0022857|GO:0055085 VAPA_1c48270 8270d7f89df2bdd78e2b259c2a8dd291 476 PRINTS PR01036 Tetracycline resistance protein TetB signature 18 42 6.4E-5 T 12-10-2018 VAPA_1c48270 8270d7f89df2bdd78e2b259c2a8dd291 476 PRINTS PR01036 Tetracycline resistance protein TetB signature 109 129 6.4E-5 T 12-10-2018 VAPA_1c48270 8270d7f89df2bdd78e2b259c2a8dd291 476 PRINTS PR01036 Tetracycline resistance protein TetB signature 139 163 6.4E-5 T 12-10-2018 VAPA_1c48270 8270d7f89df2bdd78e2b259c2a8dd291 476 PRINTS PR01036 Tetracycline resistance protein TetB signature 401 420 6.4E-5 T 12-10-2018 VAPA_1c48270 8270d7f89df2bdd78e2b259c2a8dd291 476 Gene3D G3DSA:1.20.1250.20 262 464 2.2E-14 T 12-10-2018 VAPA_1c48270 8270d7f89df2bdd78e2b259c2a8dd291 476 Pfam PF07690 Major Facilitator Superfamily 19 410 6.1E-45 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 VAPA_1c48270 8270d7f89df2bdd78e2b259c2a8dd291 476 Gene3D G3DSA:1.20.1250.20 8 197 6.6E-33 T 12-10-2018 VAPA_1c48270 8270d7f89df2bdd78e2b259c2a8dd291 476 SUPERFAMILY SSF103473 11 464 5.62E-59 T 12-10-2018 IPR036259 MFS transporter superfamily VAPA_1c38030 5b880425587d683ccd07acc4ecadd91e 553 Pfam PF12848 ABC transporter 229 305 3.1E-12 T 12-10-2018 IPR032781 ABC-transporter extension domain VAPA_1c38030 5b880425587d683ccd07acc4ecadd91e 553 Pfam PF00005 ABC transporter 22 190 4.9E-28 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c38030 5b880425587d683ccd07acc4ecadd91e 553 Gene3D G3DSA:3.40.50.300 285 552 3.8E-75 T 12-10-2018 VAPA_1c38030 5b880425587d683ccd07acc4ecadd91e 553 Pfam PF00005 ABC transporter 339 472 3.4E-25 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c38030 5b880425587d683ccd07acc4ecadd91e 553 SMART SM00382 347 525 1.5E-10 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c38030 5b880425587d683ccd07acc4ecadd91e 553 SMART SM00382 31 235 1.9E-8 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c38030 5b880425587d683ccd07acc4ecadd91e 553 SUPERFAMILY SSF52540 301 515 2.06E-48 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c38030 5b880425587d683ccd07acc4ecadd91e 553 ProSitePatterns PS00211 ABC transporters family signature. 162 176 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_1c38030 5b880425587d683ccd07acc4ecadd91e 553 TIGRFAM TIGR03719 ABC_ABC_ChvD: ATP-binding cassette protein, ChvD family 2 552 1.6E-285 T 12-10-2018 IPR022374 Energy-dependent translational throttle protein EttA GO:0045900 VAPA_1c38030 5b880425587d683ccd07acc4ecadd91e 553 SUPERFAMILY SSF52540 19 241 2.59E-47 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c38030 5b880425587d683ccd07acc4ecadd91e 553 Gene3D G3DSA:3.40.50.300 1 284 1.3E-80 T 12-10-2018 VAPA_1c23780 9b169146c8c3f3b993378d3114299418 443 TIGRFAM TIGR00184 purA: adenylosuccinate synthase 10 440 7.6E-163 T 12-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 VAPA_1c23780 9b169146c8c3f3b993378d3114299418 443 SMART SM00788 8 435 9.9E-285 T 12-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 VAPA_1c23780 9b169146c8c3f3b993378d3114299418 443 Gene3D G3DSA:1.10.300.10 106 208 1.8E-96 T 12-10-2018 VAPA_1c23780 9b169146c8c3f3b993378d3114299418 443 SUPERFAMILY SSF52540 8 440 2.34E-167 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c23780 9b169146c8c3f3b993378d3114299418 443 Hamap MF_00011 Adenylosuccinate synthetase [purA]. 1 443 205.158 T 12-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 VAPA_1c23780 9b169146c8c3f3b993378d3114299418 443 ProSitePatterns PS00513 Adenylosuccinate synthetase active site. 140 151 - T 12-10-2018 IPR033128 Adenylosuccinate synthase, active site KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 VAPA_1c23780 9b169146c8c3f3b993378d3114299418 443 Pfam PF00709 Adenylosuccinate synthetase 9 434 9.3E-169 T 12-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 VAPA_1c23780 9b169146c8c3f3b993378d3114299418 443 Gene3D G3DSA:3.40.440.10 10 265 1.8E-96 T 12-10-2018 VAPA_1c23780 9b169146c8c3f3b993378d3114299418 443 ProSitePatterns PS01266 Adenylosuccinate synthetase GTP-binding site. 15 22 - T 12-10-2018 IPR018220 Adenylosuccinate synthase, GTP-binding site GO:0005525 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 VAPA_1c23780 9b169146c8c3f3b993378d3114299418 443 Gene3D G3DSA:3.90.170.10 274 442 5.0E-64 T 12-10-2018 VAPA_1c34170 12e869357a1862d4d5bd5b43f6c9b663 726 ProSitePatterns PS00435 Peroxidases proximal heme-ligand signature. 249 259 - T 12-10-2018 IPR019793 Peroxidases heam-ligand binding site Reactome: R-HSA-2408557 VAPA_1c34170 12e869357a1862d4d5bd5b43f6c9b663 726 Gene3D G3DSA:1.10.520.10 16 420 3.5E-224 T 12-10-2018 VAPA_1c34170 12e869357a1862d4d5bd5b43f6c9b663 726 Pfam PF00141 Peroxidase 392 699 9.4E-38 T 12-10-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 VAPA_1c34170 12e869357a1862d4d5bd5b43f6c9b663 726 Pfam PF00141 Peroxidase 64 384 2.5E-48 T 12-10-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 VAPA_1c34170 12e869357a1862d4d5bd5b43f6c9b663 726 TIGRFAM TIGR00198 cat_per_HPI: catalase/peroxidase HPI 8 725 0.0 T 12-10-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|KEGG: 00983+1.11.1.21|MetaCyc: PWY-5506 VAPA_1c34170 12e869357a1862d4d5bd5b43f6c9b663 726 Gene3D G3DSA:1.10.520.10 422 725 1.4E-144 T 12-10-2018 VAPA_1c34170 12e869357a1862d4d5bd5b43f6c9b663 726 Gene3D G3DSA:1.10.420.20 186 387 3.5E-224 T 12-10-2018 VAPA_1c34170 12e869357a1862d4d5bd5b43f6c9b663 726 Hamap MF_01961 Catalase-peroxidase [katG]. 4 726 41.279 T 12-10-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|KEGG: 00983+1.11.1.21|MetaCyc: PWY-5506 VAPA_1c34170 12e869357a1862d4d5bd5b43f6c9b663 726 SUPERFAMILY SSF48113 420 725 7.81E-112 T 12-10-2018 IPR010255 Haem peroxidase GO:0004601|GO:0006979|GO:0020037|GO:0055114 VAPA_1c34170 12e869357a1862d4d5bd5b43f6c9b663 726 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 257 280 1.9E-55 T 12-10-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|KEGG: 00983+1.11.1.21|MetaCyc: PWY-5506 VAPA_1c34170 12e869357a1862d4d5bd5b43f6c9b663 726 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 470 496 1.9E-55 T 12-10-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|KEGG: 00983+1.11.1.21|MetaCyc: PWY-5506 VAPA_1c34170 12e869357a1862d4d5bd5b43f6c9b663 726 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 47 60 1.9E-55 T 12-10-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|KEGG: 00983+1.11.1.21|MetaCyc: PWY-5506 VAPA_1c34170 12e869357a1862d4d5bd5b43f6c9b663 726 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 62 87 1.9E-55 T 12-10-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|KEGG: 00983+1.11.1.21|MetaCyc: PWY-5506 VAPA_1c34170 12e869357a1862d4d5bd5b43f6c9b663 726 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 21 43 1.9E-55 T 12-10-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|KEGG: 00983+1.11.1.21|MetaCyc: PWY-5506 VAPA_1c34170 12e869357a1862d4d5bd5b43f6c9b663 726 SUPERFAMILY SSF48113 17 419 6.19E-150 T 12-10-2018 IPR010255 Haem peroxidase GO:0004601|GO:0006979|GO:0020037|GO:0055114 VAPA_1c34170 12e869357a1862d4d5bd5b43f6c9b663 726 Gene3D G3DSA:1.10.420.10 578 701 1.4E-144 T 12-10-2018 VAPA_1c34170 12e869357a1862d4d5bd5b43f6c9b663 726 ProSitePatterns PS00436 Peroxidases active site signature. 85 96 - T 12-10-2018 IPR019794 Peroxidase, active site GO:0004601|GO:0055114 VAPA_1c34170 12e869357a1862d4d5bd5b43f6c9b663 726 PRINTS PR00458 Haem peroxidase superfamily signature 308 323 1.2E-18 T 12-10-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 VAPA_1c34170 12e869357a1862d4d5bd5b43f6c9b663 726 PRINTS PR00458 Haem peroxidase superfamily signature 249 264 1.2E-18 T 12-10-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 VAPA_1c34170 12e869357a1862d4d5bd5b43f6c9b663 726 PRINTS PR00458 Haem peroxidase superfamily signature 163 175 1.2E-18 T 12-10-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 VAPA_1c34170 12e869357a1862d4d5bd5b43f6c9b663 726 PRINTS PR00458 Haem peroxidase superfamily signature 145 162 1.2E-18 T 12-10-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 VAPA_1c34170 12e869357a1862d4d5bd5b43f6c9b663 726 PRINTS PR00458 Haem peroxidase superfamily signature 85 99 1.2E-18 T 12-10-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 VAPA_1c28190 ced27a484ecd91198616729c79a5954c 283 SUPERFAMILY SSF56091 33 199 2.88E-38 T 12-10-2018 VAPA_1c28190 ced27a484ecd91198616729c79a5954c 283 SUPERFAMILY SSF50249 174 278 2.4E-28 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold VAPA_1c28190 ced27a484ecd91198616729c79a5954c 283 Pfam PF14743 DNA ligase OB-like domain 213 278 2.4E-28 T 12-10-2018 IPR029319 DNA ligase, OB-like domain VAPA_1c28190 ced27a484ecd91198616729c79a5954c 283 Gene3D G3DSA:3.30.1490.70 33 191 1.1E-51 T 12-10-2018 VAPA_1c28190 ced27a484ecd91198616729c79a5954c 283 Gene3D G3DSA:3.30.470.30 52 152 1.1E-51 T 12-10-2018 VAPA_1c28190 ced27a484ecd91198616729c79a5954c 283 Gene3D G3DSA:2.40.50.140 199 281 1.3E-6 T 12-10-2018 VAPA_1c02180 d943be8f6ed55302b40e431c7a8e76af 401 Gene3D G3DSA:3.40.50.2300 48 360 3.7E-126 T 12-10-2018 VAPA_1c02180 d943be8f6ed55302b40e431c7a8e76af 401 Pfam PF13458 Periplasmic binding protein 43 368 1.5E-70 T 12-10-2018 IPR028081 Leucine-binding protein domain VAPA_1c02180 d943be8f6ed55302b40e431c7a8e76af 401 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 337 352 6.4E-8 T 12-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 VAPA_1c02180 d943be8f6ed55302b40e431c7a8e76af 401 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 50 66 6.4E-8 T 12-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 VAPA_1c02180 d943be8f6ed55302b40e431c7a8e76af 401 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 69 87 6.4E-8 T 12-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 VAPA_1c02180 d943be8f6ed55302b40e431c7a8e76af 401 Gene3D G3DSA:3.40.50.2300 147 372 3.7E-126 T 12-10-2018 VAPA_1c02180 d943be8f6ed55302b40e431c7a8e76af 401 SUPERFAMILY SSF53822 29 387 1.94E-84 T 12-10-2018 IPR028082 Periplasmic binding protein-like I VAPA_1c09490 ea47529ab711a3eed82a77825c24fd46 312 Gene3D G3DSA:1.10.10.10 7 98 1.9E-21 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c09490 ea47529ab711a3eed82a77825c24fd46 312 SUPERFAMILY SSF46785 6 117 1.36E-22 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c09490 ea47529ab711a3eed82a77825c24fd46 312 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 11 68 1.3E-16 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c09490 ea47529ab711a3eed82a77825c24fd46 312 Pfam PF03466 LysR substrate binding domain 93 297 7.5E-36 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_1c09490 ea47529ab711a3eed82a77825c24fd46 312 Gene3D G3DSA:3.40.190.290 99 307 3.4E-37 T 12-10-2018 VAPA_1c09490 ea47529ab711a3eed82a77825c24fd46 312 SUPERFAMILY SSF53850 94 300 3.53E-39 T 12-10-2018 VAPA_2c06520 e76e1f4a2e468685b09c3afe50c4659d 322 SUPERFAMILY SSF143631 19 313 6.8E-86 T 12-10-2018 IPR003374 ApbE-like superfamily VAPA_2c06520 e76e1f4a2e468685b09c3afe50c4659d 322 Gene3D G3DSA:3.10.520.20 13 321 1.5E-99 T 12-10-2018 VAPA_2c06520 e76e1f4a2e468685b09c3afe50c4659d 322 PIRSF PIRSF006268 5 316 7.1E-79 T 12-10-2018 IPR024932 Flavin transferase ApbE GO:0017013 VAPA_2c06520 e76e1f4a2e468685b09c3afe50c4659d 322 Pfam PF02424 ApbE family 24 303 2.7E-70 T 12-10-2018 IPR024932 Flavin transferase ApbE GO:0017013 VAPA_2c09350 b4a255311b16dda0a5654c76cdb20309 114 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 42 91 4.0E-15 T 12-10-2018 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 VAPA_2c09350 b4a255311b16dda0a5654c76cdb20309 114 Pfam PF02627 Carboxymuconolactone decarboxylase family 24 106 1.5E-19 T 12-10-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 VAPA_2c09350 b4a255311b16dda0a5654c76cdb20309 114 Gene3D G3DSA:1.20.1290.10 2 112 1.3E-29 T 12-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 VAPA_2c09350 b4a255311b16dda0a5654c76cdb20309 114 SUPERFAMILY SSF69118 13 111 3.66E-26 T 12-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 VAPA_1c30310 7d1c2beb442e414f26b92842487de5c1 465 PRINTS PR00149 Fumarate lyase superfamily signature 320 336 3.3E-34 T 12-10-2018 IPR000362 Fumarate lyase family VAPA_1c30310 7d1c2beb442e414f26b92842487de5c1 465 PRINTS PR00149 Fumarate lyase superfamily signature 183 201 3.3E-34 T 12-10-2018 IPR000362 Fumarate lyase family VAPA_1c30310 7d1c2beb442e414f26b92842487de5c1 465 PRINTS PR00149 Fumarate lyase superfamily signature 137 155 3.3E-34 T 12-10-2018 IPR000362 Fumarate lyase family VAPA_1c30310 7d1c2beb442e414f26b92842487de5c1 465 PRINTS PR00149 Fumarate lyase superfamily signature 274 301 3.3E-34 T 12-10-2018 IPR000362 Fumarate lyase family VAPA_1c30310 7d1c2beb442e414f26b92842487de5c1 465 TIGRFAM TIGR00979 fumC_II: fumarate hydratase, class II 8 463 2.0E-232 T 12-10-2018 IPR005677 Fumarate hydratase, class II GO:0004333|GO:0006106|GO:0045239 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 VAPA_1c30310 7d1c2beb442e414f26b92842487de5c1 465 PRINTS PR00145 Argininosuccinate lyase family signature 178 198 4.9E-5 T 12-10-2018 VAPA_1c30310 7d1c2beb442e414f26b92842487de5c1 465 PRINTS PR00145 Argininosuccinate lyase family signature 320 336 4.9E-5 T 12-10-2018 VAPA_1c30310 7d1c2beb442e414f26b92842487de5c1 465 Gene3D G3DSA:1.10.275.10 8 141 3.2E-56 T 12-10-2018 IPR024083 Fumarase/histidase, N-terminal VAPA_1c30310 7d1c2beb442e414f26b92842487de5c1 465 Hamap MF_00743 Fumarate hydratase class II [fumC]. 7 465 91.732 T 12-10-2018 IPR005677 Fumarate hydratase, class II GO:0004333|GO:0006106|GO:0045239 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 VAPA_1c30310 7d1c2beb442e414f26b92842487de5c1 465 ProSitePatterns PS00163 Fumarate lyases signature. 320 329 - T 12-10-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 VAPA_1c30310 7d1c2beb442e414f26b92842487de5c1 465 Pfam PF10415 Fumarase C C-terminus 411 464 2.3E-25 T 12-10-2018 IPR018951 Fumarase C, C-terminal GO:0006099|GO:0016829 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 VAPA_1c30310 7d1c2beb442e414f26b92842487de5c1 465 Gene3D G3DSA:1.20.200.10 142 410 1.9E-119 T 12-10-2018 VAPA_1c30310 7d1c2beb442e414f26b92842487de5c1 465 Gene3D G3DSA:1.10.40.30 411 465 1.9E-28 T 12-10-2018 VAPA_1c30310 7d1c2beb442e414f26b92842487de5c1 465 SUPERFAMILY SSF48557 7 465 5.65E-158 T 12-10-2018 IPR008948 L-Aspartase-like GO:0003824 VAPA_1c30310 7d1c2beb442e414f26b92842487de5c1 465 Pfam PF00206 Lyase 15 345 1.4E-115 T 12-10-2018 IPR022761 Fumarate lyase, N-terminal VAPA_1c25570 8700a7728e4e158067b4a188bb3fedf3 320 Gene3D G3DSA:3.60.20.30 187 320 7.0E-50 T 12-10-2018 VAPA_1c25570 8700a7728e4e158067b4a188bb3fedf3 320 Pfam PF01112 Asparaginase 8 318 1.2E-110 T 12-10-2018 IPR000246 Peptidase T2, asparaginase 2 GO:0016787 VAPA_1c25570 8700a7728e4e158067b4a188bb3fedf3 320 SUPERFAMILY SSF56235 7 316 4.37E-92 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal VAPA_1c12980 7151ad8c43127b10a8b31e83266e04c0 176 TIGRFAM TIGR02159 PA_CoA_Oxy4: phenylacetate-CoA oxygenase, PaaJ subunit 19 176 5.7E-55 T 12-10-2018 IPR011883 Phenylacetate-CoA oxygenase, PaaJ subunit VAPA_1c12980 7151ad8c43127b10a8b31e83266e04c0 176 Gene3D G3DSA:3.30.300.130 5 103 2.2E-20 T 12-10-2018 IPR034904 Fe-S cluster assembly domain superfamily VAPA_1c12980 7151ad8c43127b10a8b31e83266e04c0 176 Pfam PF01883 Iron-sulfur cluster assembly protein 11 76 1.1E-10 T 12-10-2018 IPR002744 MIP18 family-like VAPA_1c12980 7151ad8c43127b10a8b31e83266e04c0 176 SUPERFAMILY SSF117916 10 102 9.16E-21 T 12-10-2018 IPR034904 Fe-S cluster assembly domain superfamily VAPA_1c51750 1f50376c7957740a36f81f2adfd401c4 273 Gene3D G3DSA:3.10.290.10 4 59 1.3E-20 T 12-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 VAPA_1c51750 1f50376c7957740a36f81f2adfd401c4 273 SUPERFAMILY SSF55120 67 271 3.84E-33 T 12-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 VAPA_1c51750 1f50376c7957740a36f81f2adfd401c4 273 SUPERFAMILY SSF55174 8 82 6.8E-16 T 12-10-2018 VAPA_1c51750 1f50376c7957740a36f81f2adfd401c4 273 SMART SM00363 8 64 5.5E-6 T 12-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VAPA_1c51750 1f50376c7957740a36f81f2adfd401c4 273 Pfam PF01479 S4 domain 9 51 2.2E-8 T 12-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VAPA_1c51750 1f50376c7957740a36f81f2adfd401c4 273 Gene3D G3DSA:3.30.2350.10 63 273 7.8E-44 T 12-10-2018 VAPA_1c51750 1f50376c7957740a36f81f2adfd401c4 273 Pfam PF00849 RNA pseudouridylate synthase 69 237 3.1E-12 T 12-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 VAPA_1c33930 92060510359ce1b641424b3259cb9583 241 Pfam PF01569 PAP2 superfamily 96 218 1.0E-6 T 12-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase VAPA_1c33930 92060510359ce1b641424b3259cb9583 241 Gene3D G3DSA:1.20.144.10 121 235 3.4E-6 T 12-10-2018 VAPA_1c33930 92060510359ce1b641424b3259cb9583 241 SUPERFAMILY SSF48317 26 230 1.02E-13 T 12-10-2018 IPR036938 Phosphatidic acid phosphatase type 2/haloperoxidase superfamily VAPA_1c55040 7777f14104a92d4b60d3b1bda2efa953 182 Gene3D G3DSA:3.40.50.1000 3 177 1.8E-47 T 12-10-2018 IPR023214 HAD superfamily VAPA_1c55040 7777f14104a92d4b60d3b1bda2efa953 182 SUPERFAMILY SSF56784 14 172 1.65E-37 T 12-10-2018 IPR036412 HAD-like superfamily VAPA_1c55040 7777f14104a92d4b60d3b1bda2efa953 182 PIRSF PIRSF006118 4 178 1.6E-59 T 12-10-2018 IPR010023 KdsC family GO:0016788 KEGG: 00540+3.1.3.45|MetaCyc: PWY-1269|MetaCyc: PWY-7674 VAPA_1c55040 7777f14104a92d4b60d3b1bda2efa953 182 Pfam PF08282 haloacid dehalogenase-like hydrolase 91 153 5.8E-6 T 12-10-2018 VAPA_1c55040 7777f14104a92d4b60d3b1bda2efa953 182 TIGRFAM TIGR01670 KdsC-phosphatas: 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family 17 166 3.4E-47 T 12-10-2018 IPR010023 KdsC family GO:0016788 KEGG: 00540+3.1.3.45|MetaCyc: PWY-1269|MetaCyc: PWY-7674 VAPA_2c08400 acc3e3076462efe8a0fd792433df6d9f 577 Gene3D G3DSA:2.30.110.10 413 575 1.1E-45 T 12-10-2018 IPR012349 FMN-binding split barrel GO:0048037 VAPA_2c08400 acc3e3076462efe8a0fd792433df6d9f 577 Pfam PF01613 Flavin reductase like domain 426 567 1.4E-31 T 12-10-2018 IPR002563 Flavin reductase like domain GO:0010181 VAPA_2c08400 acc3e3076462efe8a0fd792433df6d9f 577 SMART SM00903 425 568 3.5E-57 T 12-10-2018 IPR002563 Flavin reductase like domain GO:0010181 VAPA_2c08400 acc3e3076462efe8a0fd792433df6d9f 577 Gene3D G3DSA:3.50.50.60 5 323 9.4E-134 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_2c08400 acc3e3076462efe8a0fd792433df6d9f 577 Gene3D G3DSA:3.30.9.40 66 271 9.4E-134 T 12-10-2018 VAPA_2c08400 acc3e3076462efe8a0fd792433df6d9f 577 SUPERFAMILY SSF50475 416 567 1.85E-47 T 12-10-2018 VAPA_2c08400 acc3e3076462efe8a0fd792433df6d9f 577 SUPERFAMILY SSF51905 1 357 7.51E-20 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c00950 b37c7d59818b5aa907855c1362397f51 558 SUPERFAMILY SSF52096 307 552 4.33E-16 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily VAPA_1c00950 b37c7d59818b5aa907855c1362397f51 558 SUPERFAMILY SSF52096 21 270 9.73E-31 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily VAPA_1c00950 b37c7d59818b5aa907855c1362397f51 558 TIGRFAM TIGR03222 benzo_boxC: benzoyl-CoA-dihydrodiol lyase 13 558 1.3E-297 T 12-10-2018 IPR017633 Benzoyl-CoA-dihydrodiol lyase KEGG: 00362+4.1.2.44|MetaCyc: PWY-1361 VAPA_1c00950 b37c7d59818b5aa907855c1362397f51 558 Gene3D G3DSA:3.90.226.10 264 493 3.4E-297 T 12-10-2018 VAPA_1c00950 b37c7d59818b5aa907855c1362397f51 558 Gene3D G3DSA:3.90.226.10 13 558 3.4E-297 T 12-10-2018 VAPA_1c00950 b37c7d59818b5aa907855c1362397f51 558 Pfam PF00378 Enoyl-CoA hydratase/isomerase 54 242 2.5E-21 T 12-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 VAPA_1c48470 b9cb8d2b56a58062f3206c57c763d624 349 Pfam PF02423 Ornithine cyclodeaminase/mu-crystallin family 10 313 3.2E-98 T 12-10-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 VAPA_1c48470 b9cb8d2b56a58062f3206c57c763d624 349 SUPERFAMILY SSF51735 2 336 9.87E-99 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c48470 b9cb8d2b56a58062f3206c57c763d624 349 Gene3D G3DSA:3.40.50.720 126 295 6.3E-127 T 12-10-2018 VAPA_1c48470 b9cb8d2b56a58062f3206c57c763d624 349 Gene3D G3DSA:3.30.1780.10 17 333 6.3E-127 T 12-10-2018 IPR023401 Ornithine cyclodeaminase, N-terminal Reactome: R-HSA-71064 VAPA_1c48470 b9cb8d2b56a58062f3206c57c763d624 349 PIRSF PIRSF001439 16 323 3.9E-55 T 12-10-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 VAPA_2c02940 f5673bfcbc34a5033abbddc102f063ff 341 Gene3D G3DSA:3.40.190.150 47 331 1.8E-100 T 12-10-2018 VAPA_2c02940 f5673bfcbc34a5033abbddc102f063ff 341 SUPERFAMILY SSF53850 112 302 7.24E-7 T 12-10-2018 VAPA_2c02940 f5673bfcbc34a5033abbddc102f063ff 341 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 67 334 3.8E-71 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_2c02940 f5673bfcbc34a5033abbddc102f063ff 341 Gene3D G3DSA:3.40.190.10 144 266 1.8E-100 T 12-10-2018 VAPA_2c02940 f5673bfcbc34a5033abbddc102f063ff 341 PIRSF PIRSF017082 11 338 9.7E-71 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c26780 7f73c41a923ef6d8ce9a38dbe759087f 345 Gene3D G3DSA:3.90.180.10 11 331 7.4E-101 T 12-10-2018 VAPA_1c26780 7f73c41a923ef6d8ce9a38dbe759087f 345 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 61 75 - T 12-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 VAPA_1c26780 7f73c41a923ef6d8ce9a38dbe759087f 345 SMART SM00829 8 343 1.7E-4 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 VAPA_1c26780 7f73c41a923ef6d8ce9a38dbe759087f 345 Pfam PF00107 Zinc-binding dehydrogenase 179 305 8.9E-21 T 12-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 VAPA_1c26780 7f73c41a923ef6d8ce9a38dbe759087f 345 Gene3D G3DSA:3.40.50.720 156 292 7.4E-101 T 12-10-2018 VAPA_1c26780 7f73c41a923ef6d8ce9a38dbe759087f 345 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 25 138 4.9E-32 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 VAPA_1c26780 7f73c41a923ef6d8ce9a38dbe759087f 345 SUPERFAMILY SSF51735 143 310 3.02E-33 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c26780 7f73c41a923ef6d8ce9a38dbe759087f 345 SUPERFAMILY SSF50129 5 177 2.99E-52 T 12-10-2018 IPR011032 GroES-like superfamily VAPA_2c12440 2c04b9f32465ef40d8033522414f0b1c 326 Gene3D G3DSA:3.40.190.10 130 252 6.9E-97 T 12-10-2018 VAPA_2c12440 2c04b9f32465ef40d8033522414f0b1c 326 SUPERFAMILY SSF53850 38 278 6.51E-7 T 12-10-2018 VAPA_2c12440 2c04b9f32465ef40d8033522414f0b1c 326 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 51 320 1.6E-63 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_2c12440 2c04b9f32465ef40d8033522414f0b1c 326 Gene3D G3DSA:3.40.190.150 32 313 6.9E-97 T 12-10-2018 VAPA_2c12440 2c04b9f32465ef40d8033522414f0b1c 326 PIRSF PIRSF017082 1 326 5.7E-68 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c13000 3dddfab38a8b6efd3d87cfad0d2d2e5d 98 Gene3D G3DSA:3.10.20.520 3 68 4.5E-32 T 12-10-2018 IPR038693 Phenylacetyl-CoA epoxidase, subunit B VAPA_1c13000 3dddfab38a8b6efd3d87cfad0d2d2e5d 98 TIGRFAM TIGR02157 PA_CoA_Oxy2: phenylacetate-CoA oxygenase, PaaH subunit 9 98 1.5E-46 T 12-10-2018 IPR009359 Phenylacetic acid degradation B VAPA_1c13000 3dddfab38a8b6efd3d87cfad0d2d2e5d 98 PIRSF PIRSF030200 1 98 3.3E-44 T 12-10-2018 IPR009359 Phenylacetic acid degradation B VAPA_1c13000 3dddfab38a8b6efd3d87cfad0d2d2e5d 98 Pfam PF06243 Phenylacetic acid degradation B 8 94 1.9E-40 T 12-10-2018 IPR009359 Phenylacetic acid degradation B VAPA_2c08380 30216902f29a3dc3ba973e0e412a6aef 332 PIRSF PIRSF017082 2 330 6.7E-62 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_2c08380 30216902f29a3dc3ba973e0e412a6aef 332 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 54 324 3.3E-66 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_2c08380 30216902f29a3dc3ba973e0e412a6aef 332 SUPERFAMILY SSF53850 112 292 3.48E-12 T 12-10-2018 VAPA_2c08380 30216902f29a3dc3ba973e0e412a6aef 332 Gene3D G3DSA:3.40.190.150 36 321 6.4E-92 T 12-10-2018 VAPA_2c08380 30216902f29a3dc3ba973e0e412a6aef 332 Gene3D G3DSA:3.40.190.10 133 257 6.4E-92 T 12-10-2018 VAPA_1c31490 db497c0ddf8bda9ad03e378d7151c655 347 SUPERFAMILY SSF54211 20 168 2.5E-15 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold VAPA_1c31490 db497c0ddf8bda9ad03e378d7151c655 347 PIRSF PIRSF004884 15 340 1.4E-69 T 12-10-2018 IPR004422 GHMP kinase group 1 KEGG: 00790+2.4.2.54|MetaCyc: PWY-6148 VAPA_1c31490 db497c0ddf8bda9ad03e378d7151c655 347 Gene3D G3DSA:3.30.230.10 34 162 4.4E-8 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup VAPA_1c31490 db497c0ddf8bda9ad03e378d7151c655 347 TIGRFAM TIGR00144 beta_RFAP_syn: beta-ribofuranosylaminobenzene 5'-phosphate synthase family 21 337 3.4E-39 T 12-10-2018 IPR004422 GHMP kinase group 1 KEGG: 00790+2.4.2.54|MetaCyc: PWY-6148 VAPA_1c44290 767711c809a32dbaa2d1f268ed442d7d 433 Pfam PF13437 HlyD family secretion protein 302 388 7.7E-8 T 12-10-2018 VAPA_1c44290 767711c809a32dbaa2d1f268ed442d7d 433 Gene3D G3DSA:1.10.287.470 255 293 1.0E-9 T 12-10-2018 VAPA_1c44290 767711c809a32dbaa2d1f268ed442d7d 433 Gene3D G3DSA:2.40.50.100 294 331 1.0E-9 T 12-10-2018 VAPA_1c44290 767711c809a32dbaa2d1f268ed442d7d 433 Gene3D G3DSA:2.40.30.170 332 381 1.0E-9 T 12-10-2018 VAPA_1c27480 6cf06e4dfbe1923f68cc30b103ea3d20 1164 SUPERFAMILY SSF55781 221 387 1.1E-17 T 12-10-2018 VAPA_1c27480 6cf06e4dfbe1923f68cc30b103ea3d20 1164 Pfam PF13185 GAF domain 253 386 1.8E-11 T 12-10-2018 IPR003018 GAF domain GO:0005515 VAPA_1c27480 6cf06e4dfbe1923f68cc30b103ea3d20 1164 SUPERFAMILY SSF52172 772 888 5.12E-26 T 12-10-2018 IPR011006 CheY-like superfamily VAPA_1c27480 6cf06e4dfbe1923f68cc30b103ea3d20 1164 Gene3D G3DSA:3.40.50.2300 892 1026 2.1E-20 T 12-10-2018 VAPA_1c27480 6cf06e4dfbe1923f68cc30b103ea3d20 1164 Pfam PF05227 CHASE3 domain 47 179 4.1E-33 T 12-10-2018 IPR007891 CHASE3 VAPA_1c27480 6cf06e4dfbe1923f68cc30b103ea3d20 1164 SUPERFAMILY SSF52172 896 1018 1.37E-21 T 12-10-2018 IPR011006 CheY-like superfamily VAPA_1c27480 6cf06e4dfbe1923f68cc30b103ea3d20 1164 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 602 711 5.4E-28 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase VAPA_1c27480 6cf06e4dfbe1923f68cc30b103ea3d20 1164 SMART SM00388 486 554 1.4E-20 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 VAPA_1c27480 6cf06e4dfbe1923f68cc30b103ea3d20 1164 SUPERFAMILY SSF47384 471 555 8.24E-21 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 VAPA_1c27480 6cf06e4dfbe1923f68cc30b103ea3d20 1164 Gene3D G3DSA:1.10.287.130 433 552 3.3E-24 T 12-10-2018 VAPA_1c27480 6cf06e4dfbe1923f68cc30b103ea3d20 1164 Gene3D G3DSA:3.30.450.40 238 397 5.3E-11 T 12-10-2018 IPR029016 GAF-like domain superfamily VAPA_1c27480 6cf06e4dfbe1923f68cc30b103ea3d20 1164 SUPERFAMILY SSF46966 95 489 7.34E-6 T 12-10-2018 VAPA_1c27480 6cf06e4dfbe1923f68cc30b103ea3d20 1164 SUPERFAMILY SSF55874 543 714 8.38E-46 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_1c27480 6cf06e4dfbe1923f68cc30b103ea3d20 1164 SMART SM00448 771 882 3.5E-20 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_1c27480 6cf06e4dfbe1923f68cc30b103ea3d20 1164 SMART SM00448 1040 1154 3.7E-39 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_1c27480 6cf06e4dfbe1923f68cc30b103ea3d20 1164 SMART SM00448 894 1008 1.1E-14 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_1c27480 6cf06e4dfbe1923f68cc30b103ea3d20 1164 Gene3D G3DSA:3.30.565.10 553 715 5.5E-48 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_1c27480 6cf06e4dfbe1923f68cc30b103ea3d20 1164 Pfam PF00512 His Kinase A (phospho-acceptor) domain 487 554 5.7E-17 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 VAPA_1c27480 6cf06e4dfbe1923f68cc30b103ea3d20 1164 PRINTS PR00344 Bacterial sensor protein C-terminal signature 656 666 1.8E-17 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c27480 6cf06e4dfbe1923f68cc30b103ea3d20 1164 PRINTS PR00344 Bacterial sensor protein C-terminal signature 638 652 1.8E-17 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c27480 6cf06e4dfbe1923f68cc30b103ea3d20 1164 PRINTS PR00344 Bacterial sensor protein C-terminal signature 673 691 1.8E-17 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c27480 6cf06e4dfbe1923f68cc30b103ea3d20 1164 PRINTS PR00344 Bacterial sensor protein C-terminal signature 697 710 1.8E-17 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c27480 6cf06e4dfbe1923f68cc30b103ea3d20 1164 Pfam PF00072 Response regulator receiver domain 1042 1153 1.1E-28 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_1c27480 6cf06e4dfbe1923f68cc30b103ea3d20 1164 Pfam PF00072 Response regulator receiver domain 773 881 1.1E-15 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_1c27480 6cf06e4dfbe1923f68cc30b103ea3d20 1164 Pfam PF00072 Response regulator receiver domain 896 1005 8.8E-17 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_1c27480 6cf06e4dfbe1923f68cc30b103ea3d20 1164 Gene3D G3DSA:1.20.1440.210 51 176 2.2E-29 T 12-10-2018 VAPA_1c27480 6cf06e4dfbe1923f68cc30b103ea3d20 1164 SMART SM00387 601 713 1.0E-37 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase VAPA_1c27480 6cf06e4dfbe1923f68cc30b103ea3d20 1164 Gene3D G3DSA:3.40.50.12740 771 891 9.5E-27 T 12-10-2018 VAPA_1c27480 6cf06e4dfbe1923f68cc30b103ea3d20 1164 Gene3D G3DSA:3.40.50.12740 1039 1163 6.6E-44 T 12-10-2018 VAPA_1c27480 6cf06e4dfbe1923f68cc30b103ea3d20 1164 SUPERFAMILY SSF52172 1038 1159 5.27E-39 T 12-10-2018 IPR011006 CheY-like superfamily VAPA_1c13490 151e16ce6e027a1cfb8540f1d731d24a 77 Pfam PF00830 Ribosomal L28 family 3 62 2.7E-29 T 12-10-2018 IPR026569 Ribosomal protein L28/L24 GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 VAPA_1c13490 151e16ce6e027a1cfb8540f1d731d24a 77 Gene3D G3DSA:2.30.170.40 2 77 6.4E-33 T 12-10-2018 IPR037147 Ribosomal protein L28/L24 superfamily GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 VAPA_1c13490 151e16ce6e027a1cfb8540f1d731d24a 77 TIGRFAM TIGR00009 L28: ribosomal protein bL28 1 57 1.6E-28 T 12-10-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 VAPA_1c13490 151e16ce6e027a1cfb8540f1d731d24a 77 Hamap MF_00373 50S ribosomal protein L28 [rpmB]. 1 67 22.188 T 12-10-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 VAPA_1c13490 151e16ce6e027a1cfb8540f1d731d24a 77 SUPERFAMILY SSF143800 2 75 1.94E-31 T 12-10-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 VAPA_1c02900 5b831ad67f8e5d919312d5ea08d3266e 264 SUPERFAMILY SSF53639 19 230 4.32E-62 T 12-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily VAPA_1c02900 5b831ad67f8e5d919312d5ea08d3266e 264 SMART SM01007 27 211 4.2E-60 T 12-10-2018 IPR001303 Class II aldolase/adducin N-terminal VAPA_1c02900 5b831ad67f8e5d919312d5ea08d3266e 264 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 27 210 1.5E-44 T 12-10-2018 IPR001303 Class II aldolase/adducin N-terminal VAPA_1c02900 5b831ad67f8e5d919312d5ea08d3266e 264 Gene3D G3DSA:3.40.225.10 14 264 1.1E-69 T 12-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily VAPA_1c12230 e7bc7214ff9c4996bec2d071e5bc927d 213 Gene3D G3DSA:3.40.190.10 93 179 1.3E-71 T 12-10-2018 VAPA_1c12230 e7bc7214ff9c4996bec2d071e5bc927d 213 Gene3D G3DSA:3.40.190.10 3 201 1.3E-71 T 12-10-2018 VAPA_1c12230 e7bc7214ff9c4996bec2d071e5bc927d 213 SUPERFAMILY SSF53850 1 206 3.39E-68 T 12-10-2018 VAPA_1c12230 e7bc7214ff9c4996bec2d071e5bc927d 213 Hamap MF_01018 ATP phosphoribosyltransferase [hisG]. 1 211 56.111 T 12-10-2018 IPR024893 ATP phosphoribosyltransferase HisG, short form GO:0000105|GO:0003879 KEGG: 00340+2.4.2.17 VAPA_1c12230 e7bc7214ff9c4996bec2d071e5bc927d 213 TIGRFAM TIGR00070 hisG: ATP phosphoribosyltransferase 2 187 4.5E-62 T 12-10-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 VAPA_1c12230 e7bc7214ff9c4996bec2d071e5bc927d 213 ProSitePatterns PS01316 ATP phosphoribosyltransferase signature. 146 167 - T 12-10-2018 IPR018198 ATP phosphoribosyltransferase, conserved site GO:0003879 KEGG: 00340+2.4.2.17 VAPA_1c12230 e7bc7214ff9c4996bec2d071e5bc927d 213 Pfam PF01634 ATP phosphoribosyltransferase 51 205 1.4E-51 T 12-10-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 VAPA_1c54490 24b291abc1701a29f54a5dd155932eb8 310 Gene3D G3DSA:1.10.10.10 2 89 1.4E-27 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c54490 24b291abc1701a29f54a5dd155932eb8 310 Pfam PF03466 LysR substrate binding domain 87 294 5.3E-41 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_1c54490 24b291abc1701a29f54a5dd155932eb8 310 Gene3D G3DSA:3.40.190.290 91 294 3.6E-60 T 12-10-2018 VAPA_1c54490 24b291abc1701a29f54a5dd155932eb8 310 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 63 1.6E-21 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c54490 24b291abc1701a29f54a5dd155932eb8 310 SUPERFAMILY SSF53850 88 295 3.67E-43 T 12-10-2018 VAPA_1c54490 24b291abc1701a29f54a5dd155932eb8 310 SUPERFAMILY SSF46785 1 111 1.36E-21 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c44340 ce20e2cc0f3bf6124e9684ae7347f211 296 Pfam PF03466 LysR substrate binding domain 89 291 1.7E-27 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_1c44340 ce20e2cc0f3bf6124e9684ae7347f211 296 Gene3D G3DSA:3.40.190.290 93 294 1.1E-24 T 12-10-2018 VAPA_1c44340 ce20e2cc0f3bf6124e9684ae7347f211 296 Gene3D G3DSA:1.10.10.10 3 89 4.6E-18 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c44340 ce20e2cc0f3bf6124e9684ae7347f211 296 SUPERFAMILY SSF53850 91 293 2.17E-28 T 12-10-2018 VAPA_1c44340 ce20e2cc0f3bf6124e9684ae7347f211 296 SUPERFAMILY SSF46785 3 111 2.29E-18 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c44340 ce20e2cc0f3bf6124e9684ae7347f211 296 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 9 63 1.2E-15 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c22810 28abd8f815d108ef685b7c869c0de4f0 489 Gene3D G3DSA:3.40.309.10 255 449 3.4E-176 T 12-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 VAPA_1c22810 28abd8f815d108ef685b7c869c0de4f0 489 TIGRFAM TIGR03216 OH_muco_semi_DH: 2-hydroxymuconic semialdehyde dehydrogenase 3 483 2.8E-257 T 12-10-2018 IPR017628 2-hydroxymuconic semialdehyde dehydrogenase GO:0016620|GO:0055114 VAPA_1c22810 28abd8f815d108ef685b7c869c0de4f0 489 Pfam PF00171 Aldehyde dehydrogenase family 13 480 4.0E-159 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 VAPA_1c22810 28abd8f815d108ef685b7c869c0de4f0 489 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 251 258 - T 12-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 VAPA_1c22810 28abd8f815d108ef685b7c869c0de4f0 489 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 279 290 - T 12-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 VAPA_1c22810 28abd8f815d108ef685b7c869c0de4f0 489 SUPERFAMILY SSF53720 4 484 2.23E-159 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 VAPA_1c22810 28abd8f815d108ef685b7c869c0de4f0 489 Gene3D G3DSA:3.40.605.10 16 472 3.4E-176 T 12-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 VAPA_1c05160 fe9fa7f1bba4916d1a62abf60d8c368d 379 Pfam PF13458 Periplasmic binding protein 35 371 5.9E-43 T 12-10-2018 IPR028081 Leucine-binding protein domain VAPA_1c05160 fe9fa7f1bba4916d1a62abf60d8c368d 379 Gene3D G3DSA:3.40.50.2300 35 367 7.6E-84 T 12-10-2018 VAPA_1c05160 fe9fa7f1bba4916d1a62abf60d8c368d 379 SUPERFAMILY SSF53822 34 378 4.52E-53 T 12-10-2018 IPR028082 Periplasmic binding protein-like I VAPA_1c05160 fe9fa7f1bba4916d1a62abf60d8c368d 379 Gene3D G3DSA:3.40.50.2300 154 369 7.6E-84 T 12-10-2018 VAPA_2c02550 8441695ad236101a91037f87adc1e665 334 SMART SM00422 8 76 3.2E-15 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 VAPA_2c02550 8441695ad236101a91037f87adc1e665 334 SUPERFAMILY SSF46955 9 107 8.06E-21 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily VAPA_2c02550 8441695ad236101a91037f87adc1e665 334 Pfam PF13411 MerR HTH family regulatory protein 9 74 4.4E-14 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 VAPA_2c02550 8441695ad236101a91037f87adc1e665 334 SUPERFAMILY SSF52540 159 269 3.75E-8 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_2c02550 8441695ad236101a91037f87adc1e665 334 ProSitePatterns PS00552 MerR-type HTH domain signature. 11 33 - T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 VAPA_2c02550 8441695ad236101a91037f87adc1e665 334 Gene3D G3DSA:1.10.1660.10 3 119 1.4E-23 T 12-10-2018 VAPA_2c02550 8441695ad236101a91037f87adc1e665 334 Gene3D G3DSA:3.40.50.300 155 276 2.6E-5 T 12-10-2018 VAPA_1c53530 b68cd7fdbb35ec23da8d9d7e8df9a85c 154 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 32 80 3.7E-14 T 12-10-2018 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 VAPA_1c53530 b68cd7fdbb35ec23da8d9d7e8df9a85c 154 SUPERFAMILY SSF69118 7 148 1.02E-45 T 12-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 VAPA_1c53530 b68cd7fdbb35ec23da8d9d7e8df9a85c 154 Pfam PF02627 Carboxymuconolactone decarboxylase family 15 96 1.0E-17 T 12-10-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 VAPA_1c53530 b68cd7fdbb35ec23da8d9d7e8df9a85c 154 Gene3D G3DSA:1.20.1290.10 5 153 1.2E-47 T 12-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 VAPA_1c39650 5efc4fbdfc793e5d455d1d79b3bd16c4 300 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 116 298 9.0E-31 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 VAPA_1c39650 5efc4fbdfc793e5d455d1d79b3bd16c4 300 SUPERFAMILY SSF161098 94 279 2.62E-27 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c39650 5efc4fbdfc793e5d455d1d79b3bd16c4 300 Gene3D G3DSA:1.10.3720.10 88 294 8.2E-22 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c39650 5efc4fbdfc793e5d455d1d79b3bd16c4 300 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 27 74 1.8E-8 T 12-10-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain VAPA_1c39210 0df4912c19e32f5d47534de8bd4fd6ef 254 Pfam PF01799 [2Fe-2S] binding domain 147 237 4.0E-29 T 12-10-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 VAPA_1c39210 0df4912c19e32f5d47534de8bd4fd6ef 254 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 80 129 6.1E-8 T 12-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 VAPA_1c39210 0df4912c19e32f5d47534de8bd4fd6ef 254 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 30 60 0.0013 T 12-10-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal VAPA_1c39210 0df4912c19e32f5d47534de8bd4fd6ef 254 SUPERFAMILY SSF54292 76 152 1.15E-25 T 12-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 VAPA_1c39210 0df4912c19e32f5d47534de8bd4fd6ef 254 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 113 121 - T 12-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 VAPA_1c39210 0df4912c19e32f5d47534de8bd4fd6ef 254 Gene3D G3DSA:3.10.20.30 66 150 5.1E-32 T 12-10-2018 IPR012675 Beta-grasp domain superfamily VAPA_1c39210 0df4912c19e32f5d47534de8bd4fd6ef 254 Gene3D G3DSA:1.10.150.120 151 243 4.4E-32 T 12-10-2018 VAPA_1c39210 0df4912c19e32f5d47534de8bd4fd6ef 254 SUPERFAMILY SSF47741 158 242 5.1E-26 T 12-10-2018 IPR036884 [2Fe-2S]-binding domain superfamily VAPA_1c37800 96c0e03643432ee5b6b73688a93b36ff 643 SUPERFAMILY SSF63829 293 601 1.44E-11 T 12-10-2018 VAPA_1c37800 96c0e03643432ee5b6b73688a93b36ff 643 Pfam PF05787 Bacterial protein of unknown function (DUF839) 71 601 2.0E-179 T 12-10-2018 IPR008557 Protein of unknown function DUF839 VAPA_1c28390 8ae5e7dc42c4631beed0ae1aa18fa66c 290 Pfam PF01810 LysE type translocator 16 200 2.3E-30 T 12-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 VAPA_1c07680 bbf558a977754723fb0a5bc0e9be39f9 302 Gene3D G3DSA:3.40.190.290 95 300 6.3E-45 T 12-10-2018 VAPA_1c07680 bbf558a977754723fb0a5bc0e9be39f9 302 Gene3D G3DSA:1.10.10.10 3 89 1.1E-26 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c07680 bbf558a977754723fb0a5bc0e9be39f9 302 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 9 67 5.4E-22 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c07680 bbf558a977754723fb0a5bc0e9be39f9 302 SUPERFAMILY SSF53850 95 299 9.87E-46 T 12-10-2018 VAPA_1c07680 bbf558a977754723fb0a5bc0e9be39f9 302 Pfam PF03466 LysR substrate binding domain 92 298 8.3E-45 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_1c07680 bbf558a977754723fb0a5bc0e9be39f9 302 SUPERFAMILY SSF46785 7 90 2.08E-22 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c07680 bbf558a977754723fb0a5bc0e9be39f9 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 44 2.2E-9 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c07680 bbf558a977754723fb0a5bc0e9be39f9 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 44 55 2.2E-9 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c07680 bbf558a977754723fb0a5bc0e9be39f9 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 23 34 2.2E-9 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c05610 97b5339b9a658983cc9eed8754011394 413 Pfam PF07690 Major Facilitator Superfamily 24 362 4.5E-31 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 VAPA_1c05610 97b5339b9a658983cc9eed8754011394 413 Gene3D G3DSA:1.20.1250.20 7 410 1.8E-40 T 12-10-2018 VAPA_1c05610 97b5339b9a658983cc9eed8754011394 413 SUPERFAMILY SSF103473 10 407 3.14E-51 T 12-10-2018 IPR036259 MFS transporter superfamily VAPA_1c19720 8afa01d6415ac1f86fc67a0b96a6e518 158 SMART SM00422 14 84 4.8E-5 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 VAPA_1c19720 8afa01d6415ac1f86fc67a0b96a6e518 158 Pfam PF13411 MerR HTH family regulatory protein 14 83 2.7E-22 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 VAPA_1c19720 8afa01d6415ac1f86fc67a0b96a6e518 158 SUPERFAMILY SSF46955 14 118 5.49E-18 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily VAPA_1c19720 8afa01d6415ac1f86fc67a0b96a6e518 158 Gene3D G3DSA:1.10.1660.10 9 83 4.5E-21 T 12-10-2018 VAPA_1c05170 e6cf793657902163de7d07d0679fc6e1 485 PRINTS PR01036 Tetracycline resistance protein TetB signature 26 50 7.8E-8 T 12-10-2018 VAPA_1c05170 e6cf793657902163de7d07d0679fc6e1 485 PRINTS PR01036 Tetracycline resistance protein TetB signature 117 137 7.8E-8 T 12-10-2018 VAPA_1c05170 e6cf793657902163de7d07d0679fc6e1 485 PRINTS PR01036 Tetracycline resistance protein TetB signature 147 171 7.8E-8 T 12-10-2018 VAPA_1c05170 e6cf793657902163de7d07d0679fc6e1 485 PRINTS PR01036 Tetracycline resistance protein TetB signature 416 435 7.8E-8 T 12-10-2018 VAPA_1c05170 e6cf793657902163de7d07d0679fc6e1 485 SUPERFAMILY SSF103473 12 483 2.49E-56 T 12-10-2018 IPR036259 MFS transporter superfamily VAPA_1c05170 e6cf793657902163de7d07d0679fc6e1 485 Gene3D G3DSA:1.20.1720.10 23 235 1.3E-41 T 12-10-2018 VAPA_1c05170 e6cf793657902163de7d07d0679fc6e1 485 Gene3D G3DSA:1.20.1250.20 276 484 1.2E-14 T 12-10-2018 VAPA_1c05170 e6cf793657902163de7d07d0679fc6e1 485 Pfam PF07690 Major Facilitator Superfamily 28 425 6.3E-46 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 VAPA_1c05170 e6cf793657902163de7d07d0679fc6e1 485 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 23 449 9.7E-71 T 12-10-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0016021|GO:0022857|GO:0055085 VAPA_1c06280 931ad174f42bb998454b39de95059986 170 Pfam PF12790 Type VI secretion lipoprotein, VasD, EvfM, TssJ, VC_A0113 34 161 5.9E-39 T 12-10-2018 IPR017734 Type VI secretion system, lipoprotein SciN VAPA_1c06280 931ad174f42bb998454b39de95059986 170 Gene3D G3DSA:2.60.40.4150 44 170 1.0E-41 T 12-10-2018 IPR038706 Type VI secretion protein SciN-like superfamily VAPA_1c06280 931ad174f42bb998454b39de95059986 170 TIGRFAM TIGR03352 VI_chp_3: type VI secretion lipoprotein, VC_A0113 family 29 164 2.1E-40 T 12-10-2018 IPR017734 Type VI secretion system, lipoprotein SciN VAPA_1c14270 3bb7f8842229ef12cbee438be8a0ab22 426 SUPERFAMILY SSF103473 30 410 7.85E-41 T 12-10-2018 IPR036259 MFS transporter superfamily VAPA_1c14270 3bb7f8842229ef12cbee438be8a0ab22 426 Gene3D G3DSA:1.20.1250.20 227 413 1.5E-13 T 12-10-2018 VAPA_1c14270 3bb7f8842229ef12cbee438be8a0ab22 426 Gene3D G3DSA:1.20.1250.20 34 222 4.8E-15 T 12-10-2018 VAPA_1c14270 3bb7f8842229ef12cbee438be8a0ab22 426 Pfam PF07690 Major Facilitator Superfamily 56 373 8.3E-17 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 VAPA_1c05260 cb04f315547601cb07cde41ef3674078 190 SUPERFAMILY SSF82153 44 189 3.79E-39 T 12-10-2018 IPR036378 FAS1 domain superfamily VAPA_1c05260 cb04f315547601cb07cde41ef3674078 190 SMART SM00554 79 190 4.5E-27 T 12-10-2018 IPR000782 FAS1 domain VAPA_1c05260 cb04f315547601cb07cde41ef3674078 190 Pfam PF02469 Fasciclin domain 55 189 6.0E-31 T 12-10-2018 IPR000782 FAS1 domain VAPA_1c05260 cb04f315547601cb07cde41ef3674078 190 Gene3D G3DSA:2.30.180.10 20 190 1.6E-45 T 12-10-2018 IPR036378 FAS1 domain superfamily VAPA_1c47140 5b6f45007db09f6fb48ef4263dc5d65c 696 Pfam PF07696 7TMR-DISM extracellular 2 49 182 1.0E-24 T 12-10-2018 IPR011622 7TM-DISM receptor, extracellular domain, type 2 VAPA_1c47140 5b6f45007db09f6fb48ef4263dc5d65c 696 PRINTS PR00344 Bacterial sensor protein C-terminal signature 618 632 4.6E-13 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c47140 5b6f45007db09f6fb48ef4263dc5d65c 696 PRINTS PR00344 Bacterial sensor protein C-terminal signature 651 669 4.6E-13 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c47140 5b6f45007db09f6fb48ef4263dc5d65c 696 PRINTS PR00344 Bacterial sensor protein C-terminal signature 675 688 4.6E-13 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c47140 5b6f45007db09f6fb48ef4263dc5d65c 696 PRINTS PR00344 Bacterial sensor protein C-terminal signature 636 646 4.6E-13 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c47140 5b6f45007db09f6fb48ef4263dc5d65c 696 SMART SM00388 471 538 7.8E-15 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 VAPA_1c47140 5b6f45007db09f6fb48ef4263dc5d65c 696 Gene3D G3DSA:2.60.40.2380 48 188 3.9E-21 T 12-10-2018 VAPA_1c47140 5b6f45007db09f6fb48ef4263dc5d65c 696 Pfam PF00512 His Kinase A (phospho-acceptor) domain 472 536 9.2E-12 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 VAPA_1c47140 5b6f45007db09f6fb48ef4263dc5d65c 696 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 582 689 3.3E-17 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase VAPA_1c47140 5b6f45007db09f6fb48ef4263dc5d65c 696 Gene3D G3DSA:1.10.287.130 465 537 3.0E-15 T 12-10-2018 VAPA_1c47140 5b6f45007db09f6fb48ef4263dc5d65c 696 SUPERFAMILY SSF47384 455 536 1.04E-13 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 VAPA_1c47140 5b6f45007db09f6fb48ef4263dc5d65c 696 SUPERFAMILY SSF55874 528 693 1.1E-34 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_1c47140 5b6f45007db09f6fb48ef4263dc5d65c 696 SMART SM00387 581 691 3.4E-30 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase VAPA_1c47140 5b6f45007db09f6fb48ef4263dc5d65c 696 Gene3D G3DSA:3.30.565.10 564 693 1.1E-31 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_1c47140 5b6f45007db09f6fb48ef4263dc5d65c 696 Pfam PF07695 7TM diverse intracellular signalling 195 400 4.3E-14 T 12-10-2018 IPR011623 7TM-DISM receptor, extracellular domain, type 1 VAPA_1c10860 515e099bf80b54bfaa799e5dcfd28e25 556 SUPERFAMILY SSF53474 188 509 3.21E-15 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c10860 515e099bf80b54bfaa799e5dcfd28e25 556 Gene3D G3DSA:3.40.50.1820 221 511 1.5E-10 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c37620 9e5e470d33646c017e886752033dcbb7 447 SUPERFAMILY SSF103473 22 433 7.06E-64 T 12-10-2018 IPR036259 MFS transporter superfamily VAPA_1c37620 9e5e470d33646c017e886752033dcbb7 447 Gene3D G3DSA:1.20.1250.20 22 444 1.9E-63 T 12-10-2018 VAPA_1c37620 9e5e470d33646c017e886752033dcbb7 447 Pfam PF00083 Sugar (and other) transporter 28 223 1.2E-18 T 12-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 VAPA_1c37620 9e5e470d33646c017e886752033dcbb7 447 ProSitePatterns PS00217 Sugar transport proteins signature 2. 135 160 - T 12-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 VAPA_1c37620 9e5e470d33646c017e886752033dcbb7 447 ProSitePatterns PS00216 Sugar transport proteins signature 1. 304 320 - T 12-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 VAPA_1c37620 9e5e470d33646c017e886752033dcbb7 447 ProSitePatterns PS00216 Sugar transport proteins signature 1. 85 101 - T 12-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 VAPA_1c37620 9e5e470d33646c017e886752033dcbb7 447 Pfam PF07690 Major Facilitator Superfamily 256 431 5.8E-12 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 VAPA_1c52470 025e1fe2cb8dfd7eabd01eb047d414e0 177 Gene3D G3DSA:3.90.930.12 83 177 2.4E-40 T 12-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VAPA_1c52470 025e1fe2cb8dfd7eabd01eb047d414e0 177 SUPERFAMILY SSF56053 83 177 1.21E-34 T 12-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VAPA_1c52470 025e1fe2cb8dfd7eabd01eb047d414e0 177 PIRSF PIRSF002162 1 177 9.5E-51 T 12-10-2018 IPR000702 Ribosomal protein L6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VAPA_1c52470 025e1fe2cb8dfd7eabd01eb047d414e0 177 Hamap MF_01365_B 50S ribosomal protein L6 [rplF]. 1 176 35.524 T 12-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 VAPA_1c52470 025e1fe2cb8dfd7eabd01eb047d414e0 177 TIGRFAM TIGR03654 L6_bact: ribosomal protein uL6 2 176 3.5E-72 T 12-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 VAPA_1c52470 025e1fe2cb8dfd7eabd01eb047d414e0 177 SUPERFAMILY SSF56053 1 82 2.88E-23 T 12-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VAPA_1c52470 025e1fe2cb8dfd7eabd01eb047d414e0 177 ProSitePatterns PS00525 Ribosomal protein L6 signature 1. 154 162 - T 12-10-2018 IPR002358 Ribosomal protein L6, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 VAPA_1c52470 025e1fe2cb8dfd7eabd01eb047d414e0 177 PRINTS PR00059 Ribosomal protein L6 signature 99 115 3.3E-34 T 12-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 VAPA_1c52470 025e1fe2cb8dfd7eabd01eb047d414e0 177 PRINTS PR00059 Ribosomal protein L6 signature 71 96 3.3E-34 T 12-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 VAPA_1c52470 025e1fe2cb8dfd7eabd01eb047d414e0 177 PRINTS PR00059 Ribosomal protein L6 signature 141 162 3.3E-34 T 12-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 VAPA_1c52470 025e1fe2cb8dfd7eabd01eb047d414e0 177 Pfam PF00347 Ribosomal protein L6 90 164 2.9E-19 T 12-10-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VAPA_1c52470 025e1fe2cb8dfd7eabd01eb047d414e0 177 Pfam PF00347 Ribosomal protein L6 11 82 8.8E-15 T 12-10-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VAPA_1c52470 025e1fe2cb8dfd7eabd01eb047d414e0 177 Gene3D G3DSA:3.90.930.12 1 82 2.8E-26 T 12-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VAPA_2c09200 7ab82e751e697961fc19b999a98888f0 115 SUPERFAMILY SSF46785 7 111 4.88E-22 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_2c09200 7ab82e751e697961fc19b999a98888f0 115 Gene3D G3DSA:1.10.10.10 1 113 3.6E-24 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_2c09200 7ab82e751e697961fc19b999a98888f0 115 Pfam PF12840 Helix-turn-helix domain 12 70 2.3E-13 T 12-10-2018 VAPA_2c09200 7ab82e751e697961fc19b999a98888f0 115 SMART SM00418 12 89 1.5E-11 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 VAPA_1c29510 adfdb1593e70fafbbc528cb60b13faad 240 SUPERFAMILY SSF53633 7 239 1.31E-70 T 12-10-2018 IPR036393 Acetylglutamate kinase-like superfamily VAPA_1c29510 adfdb1593e70fafbbc528cb60b13faad 240 Gene3D G3DSA:3.40.1160.10 3 240 8.0E-76 T 12-10-2018 IPR036393 Acetylglutamate kinase-like superfamily VAPA_1c29510 adfdb1593e70fafbbc528cb60b13faad 240 Hamap MF_01220_B Uridylate kinase [pyrH]. 6 239 43.957 T 12-10-2018 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 VAPA_1c29510 adfdb1593e70fafbbc528cb60b13faad 240 Pfam PF00696 Amino acid kinase family 9 217 5.9E-30 T 12-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 VAPA_1c29510 adfdb1593e70fafbbc528cb60b13faad 240 PIRSF PIRSF005650 3 240 1.6E-89 T 12-10-2018 IPR011817 Uridylate kinase GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22 VAPA_1c29510 adfdb1593e70fafbbc528cb60b13faad 240 TIGRFAM TIGR02075 pyrH_bact: UMP kinase 9 239 2.0E-99 T 12-10-2018 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 VAPA_1c42870 acb5b438e324f897f980da999a9759e8 1292 Gene3D G3DSA:3.30.465.40 146 423 2.2E-35 T 12-10-2018 VAPA_1c42870 acb5b438e324f897f980da999a9759e8 1292 Gene3D G3DSA:3.30.70.2740 664 737 1.9E-6 T 12-10-2018 VAPA_1c42870 acb5b438e324f897f980da999a9759e8 1292 SUPERFAMILY SSF55103 666 777 5.23E-26 T 12-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 VAPA_1c42870 acb5b438e324f897f980da999a9759e8 1292 Pfam PF01565 FAD binding domain 186 331 1.0E-22 T 12-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 VAPA_1c42870 acb5b438e324f897f980da999a9759e8 1292 SUPERFAMILY SSF56176 150 414 2.48E-52 T 12-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 VAPA_1c42870 acb5b438e324f897f980da999a9759e8 1292 SUPERFAMILY SSF46548 792 914 1.7E-13 T 12-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 VAPA_1c42870 acb5b438e324f897f980da999a9759e8 1292 Pfam PF12447 Protein of unknown function (DUF3683) 19 136 5.4E-48 T 12-10-2018 IPR022153 Protein of unknown function DUF3683 VAPA_1c42870 acb5b438e324f897f980da999a9759e8 1292 Pfam PF13183 4Fe-4S dicluster domain 818 897 4.0E-7 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain VAPA_1c42870 acb5b438e324f897f980da999a9759e8 1292 Pfam PF02754 Cysteine-rich domain 1153 1242 5.2E-4 T 12-10-2018 IPR004017 Cysteine-rich domain VAPA_1c42870 acb5b438e324f897f980da999a9759e8 1292 Pfam PF02754 Cysteine-rich domain 1028 1117 6.7E-7 T 12-10-2018 IPR004017 Cysteine-rich domain VAPA_1c42870 acb5b438e324f897f980da999a9759e8 1292 Pfam PF11880 Domain of unknown function (DUF3400) 1245 1292 1.2E-21 T 12-10-2018 IPR021817 Protein of unknown function DUF3400 VAPA_1c42870 acb5b438e324f897f980da999a9759e8 1292 SUPERFAMILY SSF55103 419 571 9.16E-16 T 12-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 VAPA_1c42870 acb5b438e324f897f980da999a9759e8 1292 Pfam PF02913 FAD linked oxidases, C-terminal domain 443 566 2.8E-5 T 12-10-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 VAPA_1c42870 acb5b438e324f897f980da999a9759e8 1292 Pfam PF02913 FAD linked oxidases, C-terminal domain 685 773 8.7E-16 T 12-10-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 VAPA_2c02700 cedc8cffd19a1d343165e0da2bedb4b2 384 Gene3D G3DSA:3.30.9.10 88 320 2.6E-90 T 12-10-2018 VAPA_2c02700 cedc8cffd19a1d343165e0da2bedb4b2 384 Pfam PF01266 FAD dependent oxidoreductase 8 357 7.4E-57 T 12-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 VAPA_2c02700 cedc8cffd19a1d343165e0da2bedb4b2 384 SUPERFAMILY SSF51905 7 380 1.65E-55 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_2c02700 cedc8cffd19a1d343165e0da2bedb4b2 384 Gene3D G3DSA:3.50.50.60 8 364 2.6E-90 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c20510 9f5046307e4600bd760ee151bbeb2d3f 284 Gene3D G3DSA:3.40.50.1820 23 274 1.4E-37 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c20510 9f5046307e4600bd760ee151bbeb2d3f 284 SUPERFAMILY SSF53474 27 273 1.01E-34 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c20510 9f5046307e4600bd760ee151bbeb2d3f 284 Pfam PF00561 alpha/beta hydrolase fold 38 257 9.9E-15 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 VAPA_1c24730 b53c6a37214f0371f97d9d1f598b9086 344 Pfam PF09084 NMT1/THI5 like 46 259 9.3E-20 T 12-10-2018 IPR015168 SsuA/THI5-like VAPA_1c24730 b53c6a37214f0371f97d9d1f598b9086 344 Gene3D G3DSA:3.40.190.10 115 225 7.8E-114 T 12-10-2018 VAPA_1c24730 b53c6a37214f0371f97d9d1f598b9086 344 SUPERFAMILY SSF53850 32 283 5.2E-42 T 12-10-2018 VAPA_1c24730 b53c6a37214f0371f97d9d1f598b9086 344 Gene3D G3DSA:3.40.190.10 36 334 7.8E-114 T 12-10-2018 VAPA_1c15110 a142fa6c7ee8e1184dd4126ff7045ad6 909 Gene3D G3DSA:1.20.58.2200 849 908 5.3E-8 T 12-10-2018 IPR038440 FimV, C-terminal domain superfamily VAPA_1c15110 a142fa6c7ee8e1184dd4126ff7045ad6 909 TIGRFAM TIGR03505 FimV_core: FimV N-terminal domain 215 286 3.4E-21 T 12-10-2018 IPR020012 Motility protein FimV, N-terminal VAPA_1c15110 a142fa6c7ee8e1184dd4126ff7045ad6 909 TIGRFAM TIGR03504 FimV_Cterm: FimV C-terminal domain 866 908 8.9E-9 T 12-10-2018 IPR020011 Motility protein FimV, C-terminal VAPA_1c15670 e0dad39e3c0340e98bb61a719b227ecb 248 SUPERFAMILY SSF75217 1 232 5.1E-90 T 12-10-2018 IPR029028 Alpha/beta knot methyltransferases VAPA_1c15670 e0dad39e3c0340e98bb61a719b227ecb 248 PIRSF PIRSF000386 1 247 2.0E-87 T 12-10-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 VAPA_1c15670 e0dad39e3c0340e98bb61a719b227ecb 248 TIGRFAM TIGR00088 trmD: tRNA (guanine(37)-N(1))-methyltransferase 1 229 7.2E-83 T 12-10-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 VAPA_1c15670 e0dad39e3c0340e98bb61a719b227ecb 248 Pfam PF01746 tRNA (Guanine-1)-methyltransferase 24 224 6.7E-53 T 12-10-2018 IPR016009 tRNA methyltransferase TRMD/TRM10-type domain MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 VAPA_1c15670 e0dad39e3c0340e98bb61a719b227ecb 248 Hamap MF_00605 tRNA (guanine-N(1)-)-methyltransferase [trmD]. 1 248 100.83 T 12-10-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 VAPA_1c15670 e0dad39e3c0340e98bb61a719b227ecb 248 Gene3D G3DSA:3.40.1280.10 1 172 7.4E-62 T 12-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal VAPA_1c15670 e0dad39e3c0340e98bb61a719b227ecb 248 Gene3D G3DSA:1.10.1270.20 173 248 1.9E-26 T 12-10-2018 IPR023148 tRNA (guanine-N1-)-methyltransferase, C-terminal GO:0008033|GO:0052906 MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 VAPA_1c51270 4049a4e7c9949f25dca16f4bc5f63637 271 Pfam PF00378 Enoyl-CoA hydratase/isomerase 22 270 7.8E-39 T 12-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 VAPA_1c51270 4049a4e7c9949f25dca16f4bc5f63637 271 Gene3D G3DSA:1.10.12.10 214 271 2.6E-14 T 12-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal VAPA_1c51270 4049a4e7c9949f25dca16f4bc5f63637 271 SUPERFAMILY SSF52096 15 270 2.87E-60 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily VAPA_1c51270 4049a4e7c9949f25dca16f4bc5f63637 271 Gene3D G3DSA:3.90.226.10 11 213 3.5E-53 T 12-10-2018 VAPA_1c02730 b9ea7ea94741696fd4f02bc73a4b9c1a 99 Pfam PF13432 Tetratricopeptide repeat 29 70 4.1E-5 T 12-10-2018 VAPA_1c02730 b9ea7ea94741696fd4f02bc73a4b9c1a 99 Gene3D G3DSA:1.25.40.10 8 94 7.5E-11 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 VAPA_1c02730 b9ea7ea94741696fd4f02bc73a4b9c1a 99 SUPERFAMILY SSF48452 11 92 1.61E-11 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 VAPA_1c37260 3819d1dc9e76f9578dc6290e72aa76d6 288 SUPERFAMILY SSF53697 100 259 8.7E-20 T 12-10-2018 VAPA_1c37260 3819d1dc9e76f9578dc6290e72aa76d6 288 Pfam PF01418 Helix-turn-helix domain, rpiR family 1 73 3.0E-12 T 12-10-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 VAPA_1c37260 3819d1dc9e76f9578dc6290e72aa76d6 288 SUPERFAMILY SSF46689 2 73 1.09E-16 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 VAPA_1c37260 3819d1dc9e76f9578dc6290e72aa76d6 288 Gene3D G3DSA:3.40.50.10490 94 276 2.3E-26 T 12-10-2018 VAPA_1c37260 3819d1dc9e76f9578dc6290e72aa76d6 288 Gene3D G3DSA:1.10.10.10 1 79 1.2E-18 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c37260 3819d1dc9e76f9578dc6290e72aa76d6 288 Pfam PF01380 SIS domain 136 251 2.4E-9 T 12-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 VAPA_1c10170 ca30553beda2c57caca620701e6dd74a 671 Pfam PF00535 Glycosyl transferase family 2 176 363 7.5E-17 T 12-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 VAPA_1c10170 ca30553beda2c57caca620701e6dd74a 671 Gene3D G3DSA:3.90.550.10 169 407 4.4E-17 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases VAPA_1c10170 ca30553beda2c57caca620701e6dd74a 671 SUPERFAMILY SSF53448 174 466 3.38E-26 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases VAPA_1c27590 359c705e8a3b49f95dcdffbf8b0e7443 214 Gene3D G3DSA:2.30.110.10 1 202 7.3E-50 T 12-10-2018 IPR012349 FMN-binding split barrel GO:0048037 VAPA_1c27590 359c705e8a3b49f95dcdffbf8b0e7443 214 Pfam PF04299 Putative FMN-binding domain 1 162 1.3E-43 T 12-10-2018 IPR007396 Transcriptional regulator PAI 2-type VAPA_1c27590 359c705e8a3b49f95dcdffbf8b0e7443 214 PIRSF PIRSF010372 1 204 2.4E-48 T 12-10-2018 IPR007396 Transcriptional regulator PAI 2-type VAPA_1c27590 359c705e8a3b49f95dcdffbf8b0e7443 214 SUPERFAMILY SSF50475 11 177 1.55E-36 T 12-10-2018 VAPA_1c39300 e2144c8a3b78710b858faa7f33299a1c 256 SMART SM00345 26 85 1.4E-17 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_1c39300 e2144c8a3b78710b858faa7f33299a1c 256 Gene3D G3DSA:3.40.1410.10 93 250 9.5E-40 T 12-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily VAPA_1c39300 e2144c8a3b78710b858faa7f33299a1c 256 Pfam PF00392 Bacterial regulatory proteins, gntR family 22 85 7.0E-18 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_1c39300 e2144c8a3b78710b858faa7f33299a1c 256 SMART SM00866 105 247 4.7E-26 T 12-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 VAPA_1c39300 e2144c8a3b78710b858faa7f33299a1c 256 Pfam PF07702 UTRA domain 108 246 3.1E-26 T 12-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 VAPA_1c39300 e2144c8a3b78710b858faa7f33299a1c 256 SUPERFAMILY SSF64288 74 254 1.2E-32 T 12-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily VAPA_1c39300 e2144c8a3b78710b858faa7f33299a1c 256 SUPERFAMILY SSF46785 18 97 3.68E-19 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c39300 e2144c8a3b78710b858faa7f33299a1c 256 Gene3D G3DSA:1.10.10.10 16 85 1.2E-20 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c04820 fdc9df345ea842e820b735df937ea784 155 ProSitePatterns PS00372 PTS EIIA domains phosphorylation site signature 2. 52 68 - T 12-10-2018 IPR002178 PTS EIIA type-2 domain VAPA_1c04820 fdc9df345ea842e820b735df937ea784 155 SUPERFAMILY SSF55804 1 149 9.29E-39 T 12-10-2018 IPR016152 Phosphotransferase/anion transporter Reactome: R-HSA-425381 VAPA_1c04820 fdc9df345ea842e820b735df937ea784 155 Gene3D G3DSA:3.40.930.10 1 151 6.2E-50 T 12-10-2018 IPR016152 Phosphotransferase/anion transporter Reactome: R-HSA-425381 VAPA_1c04820 fdc9df345ea842e820b735df937ea784 155 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 7 146 2.3E-31 T 12-10-2018 IPR002178 PTS EIIA type-2 domain VAPA_1c05140 00ef7cf6589f0d8549e64fa926ce4720 743 Pfam PF00593 TonB dependent receptor 271 741 4.3E-36 T 12-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel VAPA_1c05140 00ef7cf6589f0d8549e64fa926ce4720 743 ProSitePatterns PS01156 TonB-dependent receptor proteins signature 2. 726 743 - T 12-10-2018 IPR010917 TonB-dependent receptor, conserved site VAPA_1c05140 00ef7cf6589f0d8549e64fa926ce4720 743 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 91 743 9.7E-104 T 12-10-2018 IPR010105 TonB-dependent siderophore receptor GO:0005506|GO:0015891|GO:0038023 VAPA_1c05140 00ef7cf6589f0d8549e64fa926ce4720 743 Pfam PF07715 TonB-dependent Receptor Plug Domain 88 185 3.6E-12 T 12-10-2018 IPR012910 TonB-dependent receptor, plug domain VAPA_1c05140 00ef7cf6589f0d8549e64fa926ce4720 743 SUPERFAMILY SSF56935 40 743 4.37E-100 T 12-10-2018 VAPA_1c05140 00ef7cf6589f0d8549e64fa926ce4720 743 Gene3D G3DSA:2.170.130.10 83 201 1.5E-17 T 12-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily VAPA_1c05140 00ef7cf6589f0d8549e64fa926ce4720 743 Gene3D G3DSA:2.40.170.20 202 743 1.3E-75 T 12-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily VAPA_1c20370 639da6bc38ecf140bea5122a8b8ce91d 129 Gene3D G3DSA:3.90.380.10 5 19 4.0E-15 T 12-10-2018 VAPA_1c20370 639da6bc38ecf140bea5122a8b8ce91d 129 SUPERFAMILY SSF50022 2 81 1.14E-18 T 12-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 VAPA_1c20370 639da6bc38ecf140bea5122a8b8ce91d 129 Pfam PF00355 Rieske [2Fe-2S] domain 24 77 1.3E-7 T 12-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 VAPA_1c20370 639da6bc38ecf140bea5122a8b8ce91d 129 Gene3D G3DSA:2.102.10.10 20 80 4.0E-15 T 12-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 VAPA_1c46020 4f651b9319c5a83d6414ae5bd618a256 139 SUPERFAMILY SSF82784 7 138 3.53E-39 T 12-10-2018 IPR036102 OsmC/Ohr superfamily VAPA_1c46020 4f651b9319c5a83d6414ae5bd618a256 139 Gene3D G3DSA:3.30.300.20 46 139 2.5E-32 T 12-10-2018 IPR015946 K homology domain-like, alpha/beta VAPA_1c46020 4f651b9319c5a83d6414ae5bd618a256 139 Pfam PF02566 OsmC-like protein 42 136 9.0E-18 T 12-10-2018 IPR003718 OsmC/Ohr family VAPA_1c46020 4f651b9319c5a83d6414ae5bd618a256 139 TIGRFAM TIGR03561 organ_hyd_perox: peroxiredoxin, Ohr subfamily 8 137 1.8E-47 T 12-10-2018 IPR019953 Organic hydroperoxide resistance protein famiy GO:0006979 VAPA_1c46020 4f651b9319c5a83d6414ae5bd618a256 139 Gene3D G3DSA:2.20.25.10 1 45 2.8E-21 T 12-10-2018 VAPA_1c44600 27037c0d9d9cafbc38ffb7c9d0262759 125 Pfam PF02924 Bacteriophage lambda head decoration protein D 10 107 2.7E-18 T 12-10-2018 IPR004195 Head decoration protein D VAPA_1c18870 4c5311ac04fb26dd4002887477043a63 332 SUPERFAMILY SSF88946 52 159 1.57E-39 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 VAPA_1c18870 4c5311ac04fb26dd4002887477043a63 332 Gene3D G3DSA:1.10.10.10 163 245 1.9E-10 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c18870 4c5311ac04fb26dd4002887477043a63 332 Pfam PF04545 Sigma-70, region 4 268 319 5.7E-12 T 12-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 VAPA_1c18870 4c5311ac04fb26dd4002887477043a63 332 Gene3D G3DSA:1.10.10.10 248 325 9.3E-19 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c18870 4c5311ac04fb26dd4002887477043a63 332 Pfam PF00140 Sigma-70 factor, region 1.2 52 84 2.3E-6 T 12-10-2018 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 VAPA_1c18870 4c5311ac04fb26dd4002887477043a63 332 Pfam PF04542 Sigma-70 region 2 90 159 2.5E-18 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 VAPA_1c18870 4c5311ac04fb26dd4002887477043a63 332 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 86 321 3.4E-32 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 VAPA_1c18870 4c5311ac04fb26dd4002887477043a63 332 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 114 127 - T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 VAPA_1c18870 4c5311ac04fb26dd4002887477043a63 332 PRINTS PR00046 Major sigma-70 factor signature 114 127 1.8E-21 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 VAPA_1c18870 4c5311ac04fb26dd4002887477043a63 332 PRINTS PR00046 Major sigma-70 factor signature 306 317 1.8E-21 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 VAPA_1c18870 4c5311ac04fb26dd4002887477043a63 332 PRINTS PR00046 Major sigma-70 factor signature 270 282 1.8E-21 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 VAPA_1c18870 4c5311ac04fb26dd4002887477043a63 332 PRINTS PR00046 Major sigma-70 factor signature 138 146 1.8E-21 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 VAPA_1c18870 4c5311ac04fb26dd4002887477043a63 332 PRINTS PR00046 Major sigma-70 factor signature 291 306 1.8E-21 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 VAPA_1c18870 4c5311ac04fb26dd4002887477043a63 332 Gene3D G3DSA:1.10.601.10 49 159 3.5E-41 T 12-10-2018 VAPA_1c18870 4c5311ac04fb26dd4002887477043a63 332 SUPERFAMILY SSF88659 230 323 7.29E-18 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like VAPA_1c51490 63ce911535582d05d84176705733a8a4 323 SUPERFAMILY SSF50475 171 292 4.62E-9 T 12-10-2018 VAPA_1c51490 63ce911535582d05d84176705733a8a4 323 Gene3D G3DSA:2.30.110.10 35 148 1.7E-5 T 12-10-2018 IPR012349 FMN-binding split barrel GO:0048037 VAPA_1c51490 63ce911535582d05d84176705733a8a4 323 Gene3D G3DSA:2.30.110.10 167 298 1.7E-10 T 12-10-2018 IPR012349 FMN-binding split barrel GO:0048037 VAPA_1c51490 63ce911535582d05d84176705733a8a4 323 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 202 272 2.0E-10 T 12-10-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 VAPA_1c51490 63ce911535582d05d84176705733a8a4 323 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 35 126 8.2E-8 T 12-10-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 VAPA_1c51490 63ce911535582d05d84176705733a8a4 323 SUPERFAMILY SSF50475 32 127 1.18E-5 T 12-10-2018 VAPA_1c31770 7b2d84862211c79027888c2b7f05071b 222 TIGRFAM TIGR00187 ribE: riboflavin synthase, alpha subunit 1 206 1.2E-51 T 12-10-2018 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 VAPA_1c31770 7b2d84862211c79027888c2b7f05071b 222 Pfam PF00677 Lumazine binding domain 3 93 6.1E-15 T 12-10-2018 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 VAPA_1c31770 7b2d84862211c79027888c2b7f05071b 222 Pfam PF00677 Lumazine binding domain 106 194 6.7E-24 T 12-10-2018 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 VAPA_1c31770 7b2d84862211c79027888c2b7f05071b 222 SUPERFAMILY SSF63380 1 98 1.11E-16 T 12-10-2018 IPR017938 Riboflavin synthase-like beta-barrel VAPA_1c31770 7b2d84862211c79027888c2b7f05071b 222 PIRSF PIRSF000498 1 219 6.2E-65 T 12-10-2018 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 VAPA_1c31770 7b2d84862211c79027888c2b7f05071b 222 Gene3D G3DSA:2.40.30.20 108 209 2.1E-32 T 12-10-2018 IPR023366 ATP synthase subunit alpha, N-terminal domain-like superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 VAPA_1c31770 7b2d84862211c79027888c2b7f05071b 222 Gene3D G3DSA:2.40.30.20 1 95 7.1E-20 T 12-10-2018 IPR023366 ATP synthase subunit alpha, N-terminal domain-like superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 VAPA_1c31770 7b2d84862211c79027888c2b7f05071b 222 SUPERFAMILY SSF63380 99 205 6.04E-30 T 12-10-2018 IPR017938 Riboflavin synthase-like beta-barrel VAPA_1c20700 f6b1a32c48de3b5b4fa8ca522e67b7ad 224 Gene3D G3DSA:3.90.25.10 28 46 6.9E-8 T 12-10-2018 VAPA_1c20700 f6b1a32c48de3b5b4fa8ca522e67b7ad 224 Gene3D G3DSA:3.40.50.720 1 27 6.9E-8 T 12-10-2018 VAPA_2c10370 e7c5b2eb4a4fd5378c6a9f7ca3085331 177 Pfam PF02627 Carboxymuconolactone decarboxylase family 50 126 4.8E-10 T 12-10-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 VAPA_2c10370 e7c5b2eb4a4fd5378c6a9f7ca3085331 177 Gene3D G3DSA:1.20.1290.10 40 176 1.4E-39 T 12-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 VAPA_2c10370 e7c5b2eb4a4fd5378c6a9f7ca3085331 177 SUPERFAMILY SSF69118 17 175 1.06E-35 T 12-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 VAPA_1c11920 02907d247133f11cb62e148e944aa212 722 Pfam PF05140 ResB-like family 27 705 1.5E-145 T 12-10-2018 IPR007816 ResB-like domain VAPA_1c15180 fbf7016dd3696b88263ab86f438a4236 436 PRINTS PR00143 Citrate synthase signature 303 323 3.3E-54 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 VAPA_1c15180 fbf7016dd3696b88263ab86f438a4236 436 PRINTS PR00143 Citrate synthase signature 387 401 3.3E-54 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 VAPA_1c15180 fbf7016dd3696b88263ab86f438a4236 436 PRINTS PR00143 Citrate synthase signature 367 383 3.3E-54 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 VAPA_1c15180 fbf7016dd3696b88263ab86f438a4236 436 PRINTS PR00143 Citrate synthase signature 169 182 3.3E-54 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 VAPA_1c15180 fbf7016dd3696b88263ab86f438a4236 436 PRINTS PR00143 Citrate synthase signature 223 238 3.3E-54 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 VAPA_1c15180 fbf7016dd3696b88263ab86f438a4236 436 PRINTS PR00143 Citrate synthase signature 245 273 3.3E-54 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 VAPA_1c15180 fbf7016dd3696b88263ab86f438a4236 436 ProSitePatterns PS00480 Citrate synthase signature. 310 322 - T 12-10-2018 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 Reactome: R-HSA-1268020|Reactome: R-HSA-71403 VAPA_1c15180 fbf7016dd3696b88263ab86f438a4236 436 TIGRFAM TIGR01798 cit_synth_I: citrate (Si)-synthase 17 430 2.2E-233 T 12-10-2018 IPR010953 Citrate synthase, type I GO:0004108|GO:0005737 VAPA_1c15180 fbf7016dd3696b88263ab86f438a4236 436 Gene3D G3DSA:1.10.230.10 272 384 2.0E-142 T 12-10-2018 IPR016143 Citrate synthase-like, small alpha subdomain VAPA_1c15180 fbf7016dd3696b88263ab86f438a4236 436 Gene3D G3DSA:2.20.28.60 5 54 5.4E-26 T 12-10-2018 VAPA_1c15180 fbf7016dd3696b88263ab86f438a4236 436 Gene3D G3DSA:1.10.580.10 61 419 2.0E-142 T 12-10-2018 IPR016142 Citrate synthase-like, large alpha subdomain Reactome: R-HSA-1268020|Reactome: R-HSA-71403 VAPA_1c15180 fbf7016dd3696b88263ab86f438a4236 436 SUPERFAMILY SSF48256 9 436 1.83E-161 T 12-10-2018 IPR036969 Citrate synthase superfamily GO:0046912 VAPA_1c15180 fbf7016dd3696b88263ab86f438a4236 436 Pfam PF00285 Citrate synthase, C-terminal domain 50 419 1.5E-129 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 VAPA_1c15180 fbf7016dd3696b88263ab86f438a4236 436 PIRSF PIRSF001369 41 436 2.6E-160 T 12-10-2018 IPR024176 Citrate synthase, bacterial-type VAPA_1c14930 71365049be2b701394d0230abc94297a 321 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 117 133 3.0E-25 T 12-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 VAPA_1c14930 71365049be2b701394d0230abc94297a 321 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 271 290 3.0E-25 T 12-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 VAPA_1c14930 71365049be2b701394d0230abc94297a 321 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 181 193 3.0E-25 T 12-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 VAPA_1c14930 71365049be2b701394d0230abc94297a 321 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 102 310 3.4E-51 T 12-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 VAPA_1c14930 71365049be2b701394d0230abc94297a 321 Gene3D G3DSA:2.10.109.10 115 311 2.8E-71 T 12-10-2018 VAPA_1c14930 71365049be2b701394d0230abc94297a 321 SUPERFAMILY SSF51306 115 317 2.04E-67 T 12-10-2018 IPR036286 LexA/Signal peptidase-like superfamily VAPA_1c14930 71365049be2b701394d0230abc94297a 321 Pfam PF10502 Signal peptidase, peptidase S26 270 308 2.4E-5 T 12-10-2018 IPR019533 Peptidase S26 VAPA_1c14930 71365049be2b701394d0230abc94297a 321 ProSitePatterns PS00761 Signal peptidases I signature 3. 276 289 - T 12-10-2018 IPR019758 Peptidase S26A, signal peptidase I, conserved site GO:0008236|GO:0016021 VAPA_1c14930 71365049be2b701394d0230abc94297a 321 ProSitePatterns PS00501 Signal peptidases I serine active site. 126 133 - T 12-10-2018 IPR019756 Peptidase S26A, signal peptidase I, serine active site GO:0008236|GO:0016021 Reactome: R-HSA-1799339|Reactome: R-HSA-381771|Reactome: R-HSA-400511|Reactome: R-HSA-422085 VAPA_1c14930 71365049be2b701394d0230abc94297a 321 Pfam PF00717 Peptidase S24-like 123 205 1.4E-20 T 12-10-2018 IPR015927 Peptidase S24/S26A/S26B/S26C VAPA_1c14930 71365049be2b701394d0230abc94297a 321 ProSitePatterns PS00760 Signal peptidases I lysine active site. 183 195 - T 12-10-2018 IPR019757 Peptidase S26A, signal peptidase I, lysine active site GO:0008236|GO:0016021 VAPA_1c14930 71365049be2b701394d0230abc94297a 321 Gene3D G3DSA:2.170.230.10 192 270 2.8E-71 T 12-10-2018 VAPA_1c03230 bd56b214aca613bacadf593478c74e68 95 Gene3D G3DSA:1.10.1220.10 13 54 5.6E-8 T 12-10-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 VAPA_1c03230 bd56b214aca613bacadf593478c74e68 95 Pfam PF01402 Ribbon-helix-helix protein, copG family 8 45 1.5E-6 T 12-10-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 VAPA_1c03230 bd56b214aca613bacadf593478c74e68 95 SUPERFAMILY SSF47598 7 47 5.56E-11 T 12-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 VAPA_1c13090 2ee37a691a9de07bf31efb0013ce44a9 337 Gene3D G3DSA:1.10.8.300 206 323 1.0E-34 T 12-10-2018 VAPA_1c13090 2ee37a691a9de07bf31efb0013ce44a9 337 PIRSF PIRSF002849 1 328 8.0E-132 T 12-10-2018 VAPA_1c13090 2ee37a691a9de07bf31efb0013ce44a9 337 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 47 177 2.1E-64 T 12-10-2018 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 VAPA_1c13090 2ee37a691a9de07bf31efb0013ce44a9 337 SUPERFAMILY SSF52540 14 298 1.58E-45 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c13090 2ee37a691a9de07bf31efb0013ce44a9 337 Gene3D G3DSA:3.40.50.300 28 194 4.8E-46 T 12-10-2018 VAPA_1c48410 9ee094dcf37b9d389a8be2a565e2f8f9 267 Pfam PF06182 ABC-2 family transporter protein 37 266 5.5E-49 T 12-10-2018 IPR010390 Protein of unknown function DUF990 VAPA_1c00160 8c6e7b5bb3c12b488984311d12b19f87 363 Pfam PF03358 NADPH-dependent FMN reductase 105 312 1.3E-29 T 12-10-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 VAPA_1c00160 8c6e7b5bb3c12b488984311d12b19f87 363 SUPERFAMILY SSF52218 100 346 1.04E-29 T 12-10-2018 IPR029039 Flavoprotein-like superfamily VAPA_1c00160 8c6e7b5bb3c12b488984311d12b19f87 363 Gene3D G3DSA:3.40.50.360 104 337 3.1E-19 T 12-10-2018 IPR029039 Flavoprotein-like superfamily VAPA_1c04520 9e7e6fb76142f74013208d992d7ee103 495 Gene3D G3DSA:3.30.420.40 258 484 2.0E-35 T 12-10-2018 VAPA_1c04520 9e7e6fb76142f74013208d992d7ee103 495 SUPERFAMILY SSF53067 6 254 1.78E-36 T 12-10-2018 VAPA_1c04520 9e7e6fb76142f74013208d992d7ee103 495 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 353 373 - T 12-10-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 VAPA_1c04520 9e7e6fb76142f74013208d992d7ee103 495 PIRSF PIRSF000538 3 492 5.6E-53 T 12-10-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 VAPA_1c04520 9e7e6fb76142f74013208d992d7ee103 495 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 262 440 6.3E-16 T 12-10-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 VAPA_1c04520 9e7e6fb76142f74013208d992d7ee103 495 SUPERFAMILY SSF53067 259 486 2.59E-30 T 12-10-2018 VAPA_1c04520 9e7e6fb76142f74013208d992d7ee103 495 Gene3D G3DSA:3.30.420.40 1 245 1.6E-44 T 12-10-2018 VAPA_1c04520 9e7e6fb76142f74013208d992d7ee103 495 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 6 250 1.0E-29 T 12-10-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 VAPA_1c10840 fa60b93c4940e95cb54ef2404a631016 440 Pfam PF01471 Putative peptidoglycan binding domain 382 437 3.2E-12 T 12-10-2018 IPR002477 Peptidoglycan binding-like VAPA_1c10840 fa60b93c4940e95cb54ef2404a631016 440 Gene3D G3DSA:1.10.101.10 371 440 5.0E-12 T 12-10-2018 IPR036366 PGBD superfamily Reactome: R-HSA-1442490|Reactome: R-HSA-1474228 VAPA_1c10840 fa60b93c4940e95cb54ef2404a631016 440 Gene3D G3DSA:1.10.530.10 113 360 8.7E-86 T 12-10-2018 VAPA_1c10840 fa60b93c4940e95cb54ef2404a631016 440 Pfam PF13406 Transglycosylase SLT domain 71 361 1.3E-110 T 12-10-2018 IPR031304 Transglycosylase SLT domain 2 VAPA_1c10840 fa60b93c4940e95cb54ef2404a631016 440 SUPERFAMILY SSF47090 378 438 3.45E-15 T 12-10-2018 IPR036365 PGBD-like superfamily VAPA_1c10840 fa60b93c4940e95cb54ef2404a631016 440 SUPERFAMILY SSF53955 64 365 1.41E-97 T 12-10-2018 IPR023346 Lysozyme-like domain superfamily VAPA_1c10840 fa60b93c4940e95cb54ef2404a631016 440 Gene3D G3DSA:1.10.8.350 83 246 8.7E-86 T 12-10-2018 VAPA_1c10840 fa60b93c4940e95cb54ef2404a631016 440 TIGRFAM TIGR02283 MltB_2: lytic murein transglycosylase 71 364 1.3E-112 T 12-10-2018 IPR011970 Lytic murein transglycosylase VAPA_1c30460 32a5b371f461da5b41a28acd53d5fdf0 438 SUPERFAMILY SSF109998 250 433 1.67E-48 T 12-10-2018 IPR027304 Trigger factor/SurA domain superfamily VAPA_1c30460 32a5b371f461da5b41a28acd53d5fdf0 438 SUPERFAMILY SSF54534 89 243 2.55E-31 T 12-10-2018 VAPA_1c30460 32a5b371f461da5b41a28acd53d5fdf0 438 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 160 231 3.8E-15 T 12-10-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain VAPA_1c30460 32a5b371f461da5b41a28acd53d5fdf0 438 Pfam PF05697 Bacterial trigger factor protein (TF) 1 142 5.3E-38 T 12-10-2018 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 VAPA_1c30460 32a5b371f461da5b41a28acd53d5fdf0 438 Pfam PF05698 Bacterial trigger factor protein (TF) C-terminus 264 417 6.1E-35 T 12-10-2018 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 VAPA_1c30460 32a5b371f461da5b41a28acd53d5fdf0 438 TIGRFAM TIGR00115 tig: trigger factor 11 417 3.5E-133 T 12-10-2018 IPR005215 Trigger factor GO:0015031 VAPA_1c30460 32a5b371f461da5b41a28acd53d5fdf0 438 Gene3D G3DSA:3.30.70.1050 1 115 8.1E-37 T 12-10-2018 IPR036611 Trigger factor ribosome-binding domain superfamily GO:0006457|GO:0015031 VAPA_1c30460 32a5b371f461da5b41a28acd53d5fdf0 438 Gene3D G3DSA:3.10.50.40 150 248 8.0E-90 T 12-10-2018 VAPA_1c30460 32a5b371f461da5b41a28acd53d5fdf0 438 Hamap MF_00303 Trigger factor [tig]. 1 423 20.823 T 12-10-2018 IPR005215 Trigger factor GO:0015031 VAPA_1c30460 32a5b371f461da5b41a28acd53d5fdf0 438 Gene3D G3DSA:1.10.3120.10 116 422 8.0E-90 T 12-10-2018 IPR037041 Trigger factor, C-terminal domain superfamily GO:0006457|GO:0015031 VAPA_1c30460 32a5b371f461da5b41a28acd53d5fdf0 438 SUPERFAMILY SSF102735 1 130 5.36E-38 T 12-10-2018 IPR036611 Trigger factor ribosome-binding domain superfamily GO:0006457|GO:0015031 VAPA_1c30460 32a5b371f461da5b41a28acd53d5fdf0 438 PIRSF PIRSF003095 1 438 9.4E-127 T 12-10-2018 IPR005215 Trigger factor GO:0015031 VAPA_2c03780 cd30df086a0ceb4d23c29d1348ecfd70 413 Gene3D G3DSA:3.90.1150.10 9 388 3.0E-116 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 VAPA_2c03780 cd30df086a0ceb4d23c29d1348ecfd70 413 Gene3D G3DSA:3.40.640.10 46 302 3.0E-116 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 VAPA_2c03780 cd30df086a0ceb4d23c29d1348ecfd70 413 Pfam PF00282 Pyridoxal-dependent decarboxylase conserved domain 90 325 1.0E-15 T 12-10-2018 IPR002129 Pyridoxal phosphate-dependent decarboxylase GO:0016831|GO:0019752|GO:0030170 VAPA_2c03780 cd30df086a0ceb4d23c29d1348ecfd70 413 SUPERFAMILY SSF53383 4 397 1.61E-91 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase VAPA_1c09750 d18d5167d5a630d6e8c1029920c506d7 262 Hamap MF_00911 Cell division protein FtsQ [ftsQ]. 13 246 19.982 T 12-10-2018 IPR026579 Cell division protein FtsQ GO:0090529 VAPA_1c09750 d18d5167d5a630d6e8c1029920c506d7 262 Gene3D G3DSA:3.10.20.310 43 112 2.1E-17 T 12-10-2018 VAPA_1c09750 d18d5167d5a630d6e8c1029920c506d7 262 Gene3D G3DSA:3.40.50.11690 113 250 1.8E-30 T 12-10-2018 VAPA_1c09750 d18d5167d5a630d6e8c1029920c506d7 262 Pfam PF08478 POTRA domain, FtsQ-type 43 112 2.9E-14 T 12-10-2018 IPR013685 POTRA domain, FtsQ-type VAPA_1c09750 d18d5167d5a630d6e8c1029920c506d7 262 Pfam PF03799 Cell division protein FtsQ 117 238 1.8E-19 T 12-10-2018 IPR005548 Cell division protein FtsQ/DivIB VAPA_1c25210 7d97266e22d088c1a53cb5a721251496 133 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 2 129 4.1E-12 T 12-10-2018 IPR019587 Polyketide cyclase/dehydrase VAPA_1c25210 7d97266e22d088c1a53cb5a721251496 133 Gene3D G3DSA:3.30.530.20 1 131 3.5E-21 T 12-10-2018 IPR023393 START-like domain superfamily VAPA_1c25210 7d97266e22d088c1a53cb5a721251496 133 SUPERFAMILY SSF55961 1 130 1.14E-22 T 12-10-2018 VAPA_1c17230 76b561def900fdad5141677fd18101e6 178 Gene3D G3DSA:1.10.530.40 1 175 1.4E-33 T 12-10-2018 VAPA_1c17230 76b561def900fdad5141677fd18101e6 178 Pfam PF00959 Phage lysozyme 53 159 8.4E-13 T 12-10-2018 IPR002196 Glycoside hydrolase, family 24 GO:0003796|GO:0009253|GO:0016998 VAPA_1c17230 76b561def900fdad5141677fd18101e6 178 SUPERFAMILY SSF53955 10 174 1.84E-33 T 12-10-2018 IPR023346 Lysozyme-like domain superfamily VAPA_1c27370 dcd0c70fe424df348c88dacee9d05e97 779 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 581 742 1.3E-30 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 VAPA_1c27370 dcd0c70fe424df348c88dacee9d05e97 779 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 242 497 5.7E-36 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 VAPA_1c27370 dcd0c70fe424df348c88dacee9d05e97 779 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 469 475 - T 12-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 VAPA_1c27370 dcd0c70fe424df348c88dacee9d05e97 779 Gene3D G3DSA:3.40.1110.10 478 596 1.6E-54 T 12-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 VAPA_1c27370 dcd0c70fe424df348c88dacee9d05e97 779 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 611 621 3.4E-16 T 12-10-2018 VAPA_1c27370 dcd0c70fe424df348c88dacee9d05e97 779 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 319 333 3.4E-16 T 12-10-2018 VAPA_1c27370 dcd0c70fe424df348c88dacee9d05e97 779 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 467 481 3.4E-16 T 12-10-2018 VAPA_1c27370 dcd0c70fe424df348c88dacee9d05e97 779 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 687 699 3.4E-16 T 12-10-2018 VAPA_1c27370 dcd0c70fe424df348c88dacee9d05e97 779 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 664 683 3.4E-16 T 12-10-2018 VAPA_1c27370 dcd0c70fe424df348c88dacee9d05e97 779 SUPERFAMILY SSF81665 258 461 4.05E-10 T 12-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 VAPA_1c27370 dcd0c70fe424df348c88dacee9d05e97 779 SUPERFAMILY SSF55008 49 116 7.33E-15 T 12-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 VAPA_1c27370 dcd0c70fe424df348c88dacee9d05e97 779 Gene3D G3DSA:2.70.150.20 262 373 3.4E-28 T 12-10-2018 VAPA_1c27370 dcd0c70fe424df348c88dacee9d05e97 779 Pfam PF00122 E1-E2 ATPase 274 446 8.6E-44 T 12-10-2018 VAPA_1c27370 dcd0c70fe424df348c88dacee9d05e97 779 Pfam PF00702 haloacid dehalogenase-like hydrolase 463 678 1.1E-30 T 12-10-2018 VAPA_1c27370 dcd0c70fe424df348c88dacee9d05e97 779 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 203 766 1.6E-141 T 12-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 VAPA_1c27370 dcd0c70fe424df348c88dacee9d05e97 779 Gene3D G3DSA:3.40.50.1000 448 716 1.6E-54 T 12-10-2018 IPR023214 HAD superfamily VAPA_1c27370 dcd0c70fe424df348c88dacee9d05e97 779 Pfam PF00403 Heavy-metal-associated domain 52 101 5.1E-10 T 12-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 VAPA_1c27370 dcd0c70fe424df348c88dacee9d05e97 779 Gene3D G3DSA:3.30.70.100 49 114 4.1E-14 T 12-10-2018 VAPA_1c27370 dcd0c70fe424df348c88dacee9d05e97 779 SUPERFAMILY SSF56784 465 763 6.92E-43 T 12-10-2018 IPR036412 HAD-like superfamily VAPA_1c27370 dcd0c70fe424df348c88dacee9d05e97 779 SUPERFAMILY SSF81653 280 369 6.15E-20 T 12-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 VAPA_1c00850 10981de899455294da81cd8cf2ffc61d 233 SUPERFAMILY SSF52540 2 227 1.3E-55 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c00850 10981de899455294da81cd8cf2ffc61d 233 Gene3D G3DSA:3.40.50.300 1 233 1.9E-58 T 12-10-2018 VAPA_1c00850 10981de899455294da81cd8cf2ffc61d 233 Pfam PF00005 ABC transporter 18 161 8.1E-30 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c00850 10981de899455294da81cd8cf2ffc61d 233 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_1c00850 10981de899455294da81cd8cf2ffc61d 233 SMART SM00382 26 202 2.9E-5 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_2c07360 30f908d95d5933599d0546a4daed2a69 144 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 105 118 5.1E-10 T 12-10-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 VAPA_2c07360 30f908d95d5933599d0546a4daed2a69 144 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 73 86 5.1E-10 T 12-10-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 VAPA_2c07360 30f908d95d5933599d0546a4daed2a69 144 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 90 104 5.1E-10 T 12-10-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 VAPA_2c07360 30f908d95d5933599d0546a4daed2a69 144 SUPERFAMILY SSF51230 71 142 4.97E-20 T 12-10-2018 IPR011053 Single hybrid motif VAPA_2c07360 30f908d95d5933599d0546a4daed2a69 144 Gene3D G3DSA:2.40.50.100 68 143 7.4E-24 T 12-10-2018 VAPA_2c07360 30f908d95d5933599d0546a4daed2a69 144 Pfam PF00364 Biotin-requiring enzyme 84 142 2.6E-17 T 12-10-2018 IPR000089 Biotin/lipoyl attachment VAPA_2c07360 30f908d95d5933599d0546a4daed2a69 144 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 100 117 - T 12-10-2018 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 VAPA_2c01410 857cc2eae82f9d1d3c1a8299ee97c23b 242 Gene3D G3DSA:1.20.120.530 99 239 2.7E-28 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal VAPA_2c01410 857cc2eae82f9d1d3c1a8299ee97c23b 242 Pfam PF07729 FCD domain 107 225 1.7E-24 T 12-10-2018 IPR011711 GntR, C-terminal VAPA_2c01410 857cc2eae82f9d1d3c1a8299ee97c23b 242 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 35 49 1.4E-8 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_2c01410 857cc2eae82f9d1d3c1a8299ee97c23b 242 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 49 65 1.4E-8 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_2c01410 857cc2eae82f9d1d3c1a8299ee97c23b 242 SUPERFAMILY SSF48008 102 231 1.18E-25 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal VAPA_2c01410 857cc2eae82f9d1d3c1a8299ee97c23b 242 SMART SM00895 104 226 1.6E-22 T 12-10-2018 IPR011711 GntR, C-terminal VAPA_2c01410 857cc2eae82f9d1d3c1a8299ee97c23b 242 SMART SM00345 16 75 1.1E-20 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_2c01410 857cc2eae82f9d1d3c1a8299ee97c23b 242 Gene3D G3DSA:1.10.10.10 1 75 1.2E-21 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_2c01410 857cc2eae82f9d1d3c1a8299ee97c23b 242 Pfam PF00392 Bacterial regulatory proteins, gntR family 12 75 3.9E-21 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_2c01410 857cc2eae82f9d1d3c1a8299ee97c23b 242 SUPERFAMILY SSF46785 5 79 1.46E-20 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c41510 4825e76d26a337966e30028069901d11 306 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 88 301 5.0E-15 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 VAPA_1c41510 4825e76d26a337966e30028069901d11 306 Gene3D G3DSA:1.10.3720.10 3 299 2.9E-48 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c41510 4825e76d26a337966e30028069901d11 306 SUPERFAMILY SSF161098 8 303 5.1E-53 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c49250 ef04ad4945d2865b7bd2ca8508bf7011 564 Gene3D G3DSA:3.30.300.310 465 564 3.2E-29 T 12-10-2018 VAPA_1c49250 ef04ad4945d2865b7bd2ca8508bf7011 564 SUPERFAMILY SSF56801 15 561 1.28E-144 T 12-10-2018 VAPA_1c49250 ef04ad4945d2865b7bd2ca8508bf7011 564 Gene3D G3DSA:3.40.50.12780 9 460 6.0E-107 T 12-10-2018 VAPA_1c49250 ef04ad4945d2865b7bd2ca8508bf7011 564 Pfam PF13193 AMP-binding enzyme C-terminal domain 478 552 1.5E-19 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain VAPA_1c49250 ef04ad4945d2865b7bd2ca8508bf7011 564 Pfam PF00501 AMP-binding enzyme 30 469 5.9E-100 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 VAPA_1c49250 ef04ad4945d2865b7bd2ca8508bf7011 564 ProSitePatterns PS00455 Putative AMP-binding domain signature. 216 227 - T 12-10-2018 IPR020845 AMP-binding, conserved site VAPA_1c49260 f210b0394242f26d77f40d68314989ac 309 Gene3D G3DSA:3.60.15.10 10 225 7.4E-37 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like VAPA_1c49260 f210b0394242f26d77f40d68314989ac 309 SMART SM00849 22 207 2.1E-23 T 12-10-2018 IPR001279 Metallo-beta-lactamase VAPA_1c49260 f210b0394242f26d77f40d68314989ac 309 Pfam PF00753 Metallo-beta-lactamase superfamily 18 207 8.6E-22 T 12-10-2018 IPR001279 Metallo-beta-lactamase VAPA_1c49260 f210b0394242f26d77f40d68314989ac 309 SUPERFAMILY SSF56281 18 230 1.44E-43 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like VAPA_1c06340 5e5a6ad1ca53c807e7d96bc77ac0fd5c 332 Gene3D G3DSA:3.90.650.10 153 316 3.5E-18 T 12-10-2018 IPR036676 PurM-like, C-terminal domain superfamily VAPA_1c06340 5e5a6ad1ca53c807e7d96bc77ac0fd5c 332 SUPERFAMILY SSF55326 44 156 1.36E-24 T 12-10-2018 IPR036921 PurM-like, N-terminal domain superfamily VAPA_1c06340 5e5a6ad1ca53c807e7d96bc77ac0fd5c 332 Gene3D G3DSA:3.30.1330.10 21 152 5.3E-23 T 12-10-2018 IPR036921 PurM-like, N-terminal domain superfamily VAPA_1c06340 5e5a6ad1ca53c807e7d96bc77ac0fd5c 332 PIRSF PIRSF036540 2 324 3.9E-95 T 12-10-2018 IPR011413 Uncharacterised conserved protein UCP036540 VAPA_1c06340 5e5a6ad1ca53c807e7d96bc77ac0fd5c 332 SUPERFAMILY SSF56042 164 314 1.09E-23 T 12-10-2018 IPR036676 PurM-like, C-terminal domain superfamily VAPA_1c06340 5e5a6ad1ca53c807e7d96bc77ac0fd5c 332 Pfam PF02769 AIR synthase related protein, C-terminal domain 202 304 2.3E-12 T 12-10-2018 IPR010918 PurM-like, C-terminal domain VAPA_1c06340 5e5a6ad1ca53c807e7d96bc77ac0fd5c 332 TIGRFAM TIGR04049 AIR_rel_sll0787: AIR synthase-related protein, sll0787 family 6 323 1.0E-143 T 12-10-2018 IPR024030 AIR synthase-related protein, sll0787 family VAPA_1c06340 5e5a6ad1ca53c807e7d96bc77ac0fd5c 332 Pfam PF00586 AIR synthase related protein, N-terminal domain 49 154 6.9E-18 T 12-10-2018 IPR016188 PurM-like, N-terminal domain VAPA_1c45330 df7294d785d26a66c12d5405a7955359 531 Gene3D G3DSA:3.20.20.140 328 457 1.0E-16 T 12-10-2018 VAPA_1c45330 df7294d785d26a66c12d5405a7955359 531 Gene3D G3DSA:3.20.20.140 86 327 6.2E-61 T 12-10-2018 VAPA_1c45330 df7294d785d26a66c12d5405a7955359 531 SUPERFAMILY SSF51556 87 462 5.11E-59 T 12-10-2018 IPR032466 Metal-dependent hydrolase VAPA_1c45330 df7294d785d26a66c12d5405a7955359 531 SUPERFAMILY SSF51338 23 514 1.11E-23 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 VAPA_1c45330 df7294d785d26a66c12d5405a7955359 531 Pfam PF07969 Amidohydrolase family 75 505 7.7E-23 T 12-10-2018 IPR013108 Amidohydrolase 3 VAPA_1c44260 64e6f85f65b82408d3e035f88fcac032 93 Pfam PF00216 Bacterial DNA-binding protein 1 90 3.0E-32 T 12-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 VAPA_1c44260 64e6f85f65b82408d3e035f88fcac032 93 PRINTS PR01727 Prokaryotic integration host factor signature 74 88 1.9E-16 T 12-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 VAPA_1c44260 64e6f85f65b82408d3e035f88fcac032 93 PRINTS PR01727 Prokaryotic integration host factor signature 40 55 1.9E-16 T 12-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 VAPA_1c44260 64e6f85f65b82408d3e035f88fcac032 93 PRINTS PR01727 Prokaryotic integration host factor signature 58 71 1.9E-16 T 12-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 VAPA_1c44260 64e6f85f65b82408d3e035f88fcac032 93 SMART SM00411 1 90 5.3E-41 T 12-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 VAPA_1c44260 64e6f85f65b82408d3e035f88fcac032 93 Gene3D G3DSA:4.10.520.10 1 92 8.0E-35 T 12-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 VAPA_1c44260 64e6f85f65b82408d3e035f88fcac032 93 SUPERFAMILY SSF47729 1 91 3.68E-31 T 12-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 VAPA_1c44260 64e6f85f65b82408d3e035f88fcac032 93 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 46 65 - T 12-10-2018 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 VAPA_2c00790 c86e6da837ad73f23ad0289d8a7c0ecc 170 Pfam PF01638 HxlR-like helix-turn-helix 23 110 1.1E-24 T 12-10-2018 IPR002577 Helix-turn-helix, HxlR type VAPA_2c00790 c86e6da837ad73f23ad0289d8a7c0ecc 170 Gene3D G3DSA:1.10.10.10 8 169 5.6E-44 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_2c00790 c86e6da837ad73f23ad0289d8a7c0ecc 170 SUPERFAMILY SSF46785 12 146 1.11E-33 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c36870 c404f91b5e6d371003fde148b9ceb4d3 152 Pfam PF13412 Winged helix-turn-helix DNA-binding 4 50 4.4E-15 T 12-10-2018 VAPA_1c36870 c404f91b5e6d371003fde148b9ceb4d3 152 SUPERFAMILY SSF46785 3 63 4.1E-18 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c36870 c404f91b5e6d371003fde148b9ceb4d3 152 SUPERFAMILY SSF54909 65 137 1.43E-16 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel VAPA_1c36870 c404f91b5e6d371003fde148b9ceb4d3 152 Gene3D G3DSA:1.10.10.10 1 54 8.7E-21 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c36870 c404f91b5e6d371003fde148b9ceb4d3 152 Pfam PF01037 Lrp/AsnC ligand binding domain 70 135 8.2E-16 T 12-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain VAPA_1c36870 c404f91b5e6d371003fde148b9ceb4d3 152 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 30 49 1.2E-13 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 VAPA_1c36870 c404f91b5e6d371003fde148b9ceb4d3 152 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 3 19 1.2E-13 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 VAPA_1c36870 c404f91b5e6d371003fde148b9ceb4d3 152 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 19 30 1.2E-13 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 VAPA_1c36870 c404f91b5e6d371003fde148b9ceb4d3 152 SMART SM00344 3 109 8.0E-34 T 12-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 VAPA_1c36870 c404f91b5e6d371003fde148b9ceb4d3 152 ProSitePatterns PS00519 AsnC-type HTH domain signature. 21 47 - T 12-10-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site VAPA_1c36870 c404f91b5e6d371003fde148b9ceb4d3 152 Gene3D G3DSA:3.30.70.920 55 137 9.2E-23 T 12-10-2018 VAPA_1c30450 1cc09ee71038c49ae20e6c2e466a957c 202 Pfam PF00574 Clp protease 21 200 6.9E-88 T 12-10-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA VAPA_1c30450 1cc09ee71038c49ae20e6c2e466a957c 202 Gene3D G3DSA:3.90.226.10 2 202 9.7E-85 T 12-10-2018 VAPA_1c30450 1cc09ee71038c49ae20e6c2e466a957c 202 TIGRFAM TIGR00493 clpP: ATP-dependent Clp endopeptidase, proteolytic subunit ClpP 10 200 3.1E-105 T 12-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 VAPA_1c30450 1cc09ee71038c49ae20e6c2e466a957c 202 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 11 201 44.48 T 12-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 VAPA_1c30450 1cc09ee71038c49ae20e6c2e466a957c 202 PRINTS PR00127 Clp protease catalytic subunit P signature 176 195 1.9E-51 T 12-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 VAPA_1c30450 1cc09ee71038c49ae20e6c2e466a957c 202 PRINTS PR00127 Clp protease catalytic subunit P signature 119 138 1.9E-51 T 12-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 VAPA_1c30450 1cc09ee71038c49ae20e6c2e466a957c 202 PRINTS PR00127 Clp protease catalytic subunit P signature 27 42 1.9E-51 T 12-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 VAPA_1c30450 1cc09ee71038c49ae20e6c2e466a957c 202 PRINTS PR00127 Clp protease catalytic subunit P signature 67 87 1.9E-51 T 12-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 VAPA_1c30450 1cc09ee71038c49ae20e6c2e466a957c 202 PRINTS PR00127 Clp protease catalytic subunit P signature 98 115 1.9E-51 T 12-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 VAPA_1c30450 1cc09ee71038c49ae20e6c2e466a957c 202 SUPERFAMILY SSF52096 19 199 1.49E-74 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily VAPA_1c30450 1cc09ee71038c49ae20e6c2e466a957c 202 ProSitePatterns PS00381 Endopeptidase Clp serine active site. 98 109 - T 12-10-2018 IPR018215 ClpP, Ser active site VAPA_1c50030 87a650ed356297a47745b737508127a6 474 Pfam PF02321 Outer membrane efflux protein 285 464 1.6E-27 T 12-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 VAPA_1c50030 87a650ed356297a47745b737508127a6 474 Pfam PF02321 Outer membrane efflux protein 63 253 1.4E-26 T 12-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 VAPA_1c50030 87a650ed356297a47745b737508127a6 474 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 11 466 1.3E-126 T 12-10-2018 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0016020|GO:0022857|GO:0055085 VAPA_1c50030 87a650ed356297a47745b737508127a6 474 Gene3D G3DSA:1.20.1600.10 53 467 6.5E-143 T 12-10-2018 VAPA_1c50030 87a650ed356297a47745b737508127a6 474 SUPERFAMILY SSF56954 2 469 1.96E-114 T 12-10-2018 VAPA_1c50030 87a650ed356297a47745b737508127a6 474 Gene3D G3DSA:2.20.200.10 99 355 6.5E-143 T 12-10-2018 VAPA_1c31640 0641ecee93165ee662f62b638ae6b2f4 97 Pfam PF08734 GYD domain 4 92 2.8E-26 T 12-10-2018 IPR014845 Protein GYD/TTHA1554 VAPA_2c03720 14538d85d1af5fc435ea82cd0b70267e 315 Gene3D G3DSA:1.10.10.60 206 314 5.1E-25 T 12-10-2018 VAPA_2c03720 14538d85d1af5fc435ea82cd0b70267e 315 Pfam PF14525 AraC-binding-like domain 22 193 4.4E-20 T 12-10-2018 IPR035418 Transcription regulator HTH, AraC- type, ligand binding domain-like VAPA_2c03720 14538d85d1af5fc435ea82cd0b70267e 315 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 295 311 3.6E-5 T 12-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 VAPA_2c03720 14538d85d1af5fc435ea82cd0b70267e 315 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 280 295 3.6E-5 T 12-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 VAPA_2c03720 14538d85d1af5fc435ea82cd0b70267e 315 SUPERFAMILY SSF46689 264 313 3.72E-9 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 VAPA_2c03720 14538d85d1af5fc435ea82cd0b70267e 315 SMART SM00342 228 311 1.4E-22 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 VAPA_2c03720 14538d85d1af5fc435ea82cd0b70267e 315 Pfam PF12833 Helix-turn-helix domain 235 312 1.2E-21 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 VAPA_1c39390 497b45ef5bba74322cc4b6c333019a3e 327 Pfam PF12556 Cobaltochelatase CobS subunit N terminal 8 37 2.6E-17 T 12-10-2018 IPR025865 Cobaltochelatase subunit CobS N-terminal domain KEGG: 00860+6.6.1.2|MetaCyc: PWY-7376 VAPA_1c39390 497b45ef5bba74322cc4b6c333019a3e 327 Pfam PF08406 CbbQ/NirQ/NorQ C-terminal 238 296 3.3E-4 T 12-10-2018 IPR013615 CbbQ/NirQ/NorQ, C-terminal VAPA_1c39390 497b45ef5bba74322cc4b6c333019a3e 327 Gene3D G3DSA:3.40.50.300 48 227 7.3E-21 T 12-10-2018 VAPA_1c39390 497b45ef5bba74322cc4b6c333019a3e 327 SUPERFAMILY SSF52540 50 281 1.37E-29 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c39390 497b45ef5bba74322cc4b6c333019a3e 327 Pfam PF07728 AAA domain (dynein-related subfamily) 64 189 2.2E-10 T 12-10-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 VAPA_1c52250 753d82133eeece75e969fa9c185649ea 308 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 63 2.6E-21 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c52250 753d82133eeece75e969fa9c185649ea 308 SUPERFAMILY SSF46785 4 85 1.32E-21 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c52250 753d82133eeece75e969fa9c185649ea 308 SUPERFAMILY SSF53850 89 299 3.44E-41 T 12-10-2018 VAPA_1c52250 753d82133eeece75e969fa9c185649ea 308 Pfam PF03466 LysR substrate binding domain 88 296 1.2E-43 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_1c52250 753d82133eeece75e969fa9c185649ea 308 Gene3D G3DSA:3.40.190.290 91 296 5.3E-58 T 12-10-2018 VAPA_1c52250 753d82133eeece75e969fa9c185649ea 308 Gene3D G3DSA:1.10.10.10 3 88 1.2E-25 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c52250 753d82133eeece75e969fa9c185649ea 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 8.2E-7 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c52250 753d82133eeece75e969fa9c185649ea 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 8.2E-7 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c52250 753d82133eeece75e969fa9c185649ea 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 8.2E-7 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c13530 39b95ee4e9eb47858f6af3850752f372 210 Hamap MF_00240 Outer-membrane lipoprotein carrier protein [lolA]. 6 210 27.152 T 12-10-2018 IPR018323 Outer membrane lipoprotein carrier protein LolA, Proteobacteria GO:0042597|GO:0042953|GO:0042954 VAPA_1c13530 39b95ee4e9eb47858f6af3850752f372 210 TIGRFAM TIGR00547 lolA: outer membrane lipoprotein carrier protein LolA 7 208 4.7E-19 T 12-10-2018 IPR018323 Outer membrane lipoprotein carrier protein LolA, Proteobacteria GO:0042597|GO:0042953|GO:0042954 VAPA_1c13530 39b95ee4e9eb47858f6af3850752f372 210 Pfam PF03548 Outer membrane lipoprotein carrier protein LolA 31 200 7.3E-42 T 12-10-2018 IPR004564 Outer membrane lipoprotein carrier protein LolA-like VAPA_1c13530 39b95ee4e9eb47858f6af3850752f372 210 SUPERFAMILY SSF89392 22 210 2.35E-44 T 12-10-2018 IPR029046 Lipoprotein localisation LolA/LolB/LppX VAPA_1c13530 39b95ee4e9eb47858f6af3850752f372 210 Gene3D G3DSA:2.50.20.10 21 209 2.9E-52 T 12-10-2018 VAPA_1c41660 b9a7c1f59aeaac66265454c93d2fb699 305 Gene3D G3DSA:3.40.50.300 11 285 7.6E-96 T 12-10-2018 VAPA_1c41660 b9a7c1f59aeaac66265454c93d2fb699 305 SUPERFAMILY SSF52540 81 269 3.78E-30 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c41660 b9a7c1f59aeaac66265454c93d2fb699 305 Pfam PF03976 Polyphosphate kinase 2 (PPK2) 51 276 3.0E-111 T 12-10-2018 IPR022488 Polyphosphate kinase-2-related VAPA_1c41660 b9a7c1f59aeaac66265454c93d2fb699 305 TIGRFAM TIGR03707 PPK2_P_aer: polyphosphate kinase 2 50 275 3.5E-114 T 12-10-2018 IPR022486 Polyphosphate kinase 2, PA0141 GO:0006793|GO:0008976 KEGG: 00190+2.7.4.1 VAPA_1c41660 b9a7c1f59aeaac66265454c93d2fb699 305 PIRSF PIRSF028756 15 305 4.9E-134 T 12-10-2018 IPR016898 Polyphosphate kinase 2 KEGG: 00190+2.7.4.1 VAPA_1c46350 568ee773127c53759cedb65a76545453 1023 SUPERFAMILY SSF48208 208 413 4.08E-12 T 12-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 VAPA_1c46350 568ee773127c53759cedb65a76545453 1023 Gene3D G3DSA:3.40.1190.10 653 876 1.6E-26 T 12-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 VAPA_1c46350 568ee773127c53759cedb65a76545453 1023 SUPERFAMILY SSF53244 890 1019 2.75E-26 T 12-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 VAPA_1c46350 568ee773127c53759cedb65a76545453 1023 Pfam PF02875 Mur ligase family, glutamate ligase domain 893 963 2.0E-5 T 12-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 VAPA_1c46350 568ee773127c53759cedb65a76545453 1023 Gene3D G3DSA:1.50.10.10 199 430 9.0E-6 T 12-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 VAPA_1c46350 568ee773127c53759cedb65a76545453 1023 Pfam PF08245 Mur ligase middle domain 680 858 3.5E-13 T 12-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 VAPA_1c46350 568ee773127c53759cedb65a76545453 1023 Gene3D G3DSA:3.90.190.20 886 1022 5.5E-27 T 12-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 VAPA_1c46350 568ee773127c53759cedb65a76545453 1023 SUPERFAMILY SSF53623 680 878 6.8E-24 T 12-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 VAPA_1c07500 2b8bb1b4476ef906cd0b20ed783d1fd2 58 Gene3D G3DSA:3.30.160.390 2 53 3.2E-9 T 12-10-2018 IPR038488 Integrase, DNA-binding domain superfamily VAPA_1c28090 af8a482b1e9e0edb5c265d080dfd57c7 123 ProDom PD007327 FACTOR A RIBOSOME-BINDING PROCESSING RRNA 3D-STRUCTURE RIBOSOMAL-BINDING PRECURSOR A RBFA 15 99 1.0E-39 T 12-10-2018 IPR000238 Ribosome-binding factor A GO:0006364 VAPA_1c28090 af8a482b1e9e0edb5c265d080dfd57c7 123 TIGRFAM TIGR00082 rbfA: ribosome-binding factor A 10 114 8.0E-26 T 12-10-2018 IPR000238 Ribosome-binding factor A GO:0006364 VAPA_1c28090 af8a482b1e9e0edb5c265d080dfd57c7 123 Pfam PF02033 Ribosome-binding factor A 11 112 1.1E-28 T 12-10-2018 IPR000238 Ribosome-binding factor A GO:0006364 VAPA_1c28090 af8a482b1e9e0edb5c265d080dfd57c7 123 SUPERFAMILY SSF89919 9 114 3.66E-31 T 12-10-2018 IPR023799 Ribosome-binding factor A domain superfamily VAPA_1c28090 af8a482b1e9e0edb5c265d080dfd57c7 123 Gene3D G3DSA:3.30.300.20 8 120 9.1E-30 T 12-10-2018 IPR015946 K homology domain-like, alpha/beta VAPA_1c28090 af8a482b1e9e0edb5c265d080dfd57c7 123 Hamap MF_00003 Ribosome-binding factor A [rbfA]. 10 112 25.04 T 12-10-2018 IPR000238 Ribosome-binding factor A GO:0006364 VAPA_2c12770 49137dd3f4a470110d0ca25508eb7892 89 SUPERFAMILY SSF143011 22 85 2.35E-6 T 12-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily VAPA_2c12770 49137dd3f4a470110d0ca25508eb7892 89 Gene3D G3DSA:3.30.2310.20 1 89 1.8E-10 T 12-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily VAPA_2c12770 49137dd3f4a470110d0ca25508eb7892 89 Pfam PF05015 RelE-like toxin of type II toxin-antitoxin system HigB 6 89 1.5E-7 T 12-10-2018 IPR007711 Toxin HigB-1 VAPA_1c41910 073e70a742a62701c704bd9cc511c5ac 229 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 90 189 4.3E-16 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 VAPA_1c41910 073e70a742a62701c704bd9cc511c5ac 229 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 2 13 3.6E-10 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 VAPA_1c41910 073e70a742a62701c704bd9cc511c5ac 229 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 102 115 3.6E-10 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 VAPA_1c41910 073e70a742a62701c704bd9cc511c5ac 229 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 133 149 3.6E-10 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 VAPA_1c41910 073e70a742a62701c704bd9cc511c5ac 229 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 151 171 3.6E-10 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 VAPA_1c41910 073e70a742a62701c704bd9cc511c5ac 229 SUPERFAMILY SSF56784 1 221 2.0E-50 T 12-10-2018 IPR036412 HAD-like superfamily VAPA_1c41910 073e70a742a62701c704bd9cc511c5ac 229 Pfam PF13419 Haloacid dehalogenase-like hydrolase 6 189 7.0E-26 T 12-10-2018 VAPA_1c41910 073e70a742a62701c704bd9cc511c5ac 229 Gene3D G3DSA:3.40.50.1000 5 196 2.6E-50 T 12-10-2018 IPR023214 HAD superfamily VAPA_1c41910 073e70a742a62701c704bd9cc511c5ac 229 Gene3D G3DSA:1.10.150.240 15 89 2.6E-50 T 12-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 VAPA_2c04810 de6682ef41d9ad0fada7f9680f57507d 104 Pfam PF04972 BON domain 37 104 1.7E-18 T 12-10-2018 IPR007055 BON domain VAPA_2c04810 de6682ef41d9ad0fada7f9680f57507d 104 SMART SM00749 42 104 7.9E-5 T 12-10-2018 IPR014004 Transport-associated and nodulation domain, bacteria VAPA_1c08990 ed9d3b6cb14290842108595b49c5c9c1 332 Gene3D G3DSA:3.40.190.150 35 322 9.8E-106 T 12-10-2018 VAPA_1c08990 ed9d3b6cb14290842108595b49c5c9c1 332 Gene3D G3DSA:3.40.190.10 132 257 9.8E-106 T 12-10-2018 VAPA_1c08990 ed9d3b6cb14290842108595b49c5c9c1 332 PIRSF PIRSF017082 5 332 5.1E-77 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c08990 ed9d3b6cb14290842108595b49c5c9c1 332 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 55 328 1.8E-77 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c08990 ed9d3b6cb14290842108595b49c5c9c1 332 SUPERFAMILY SSF53850 95 294 4.51E-13 T 12-10-2018 VAPA_1c39540 4b73bfa89bf09e5262d5bcbb8de73b52 435 Gene3D G3DSA:1.10.760.10 311 435 2.0E-23 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 VAPA_1c39540 4b73bfa89bf09e5262d5bcbb8de73b52 435 SUPERFAMILY SSF46626 32 169 1.28E-23 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 VAPA_1c39540 4b73bfa89bf09e5262d5bcbb8de73b52 435 Gene3D G3DSA:1.10.760.10 167 306 1.4E-6 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 VAPA_1c39540 4b73bfa89bf09e5262d5bcbb8de73b52 435 PIRSF PIRSF000018 15 435 1.2E-132 T 12-10-2018 IPR014353 Membrane-bound alcohol dehydrogenase, cytochrome c subunit GO:0005506|GO:0016020|GO:0016614|GO:0020037 VAPA_1c39540 4b73bfa89bf09e5262d5bcbb8de73b52 435 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 334 413 4.5E-9 T 12-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 VAPA_1c39540 4b73bfa89bf09e5262d5bcbb8de73b52 435 Gene3D G3DSA:1.10.760.10 1 157 2.4E-11 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 VAPA_1c39540 4b73bfa89bf09e5262d5bcbb8de73b52 435 SUPERFAMILY SSF46626 312 426 1.76E-19 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 VAPA_1c39540 4b73bfa89bf09e5262d5bcbb8de73b52 435 SUPERFAMILY SSF46626 190 298 2.44E-17 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 VAPA_1c52930 a48dca74fe0cd87a046f7ff777f7d8d5 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 8.0E-9 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c52930 a48dca74fe0cd87a046f7ff777f7d8d5 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 8.0E-9 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c52930 a48dca74fe0cd87a046f7ff777f7d8d5 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 8.0E-9 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c52930 a48dca74fe0cd87a046f7ff777f7d8d5 301 SUPERFAMILY SSF46785 2 112 5.31E-25 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c52930 a48dca74fe0cd87a046f7ff777f7d8d5 301 Gene3D G3DSA:3.40.190.290 92 298 1.1E-38 T 12-10-2018 VAPA_1c52930 a48dca74fe0cd87a046f7ff777f7d8d5 301 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 64 6.1E-22 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c52930 a48dca74fe0cd87a046f7ff777f7d8d5 301 SUPERFAMILY SSF53850 91 297 6.67E-37 T 12-10-2018 VAPA_1c52930 a48dca74fe0cd87a046f7ff777f7d8d5 301 Gene3D G3DSA:1.10.10.10 1 85 1.6E-26 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c52930 a48dca74fe0cd87a046f7ff777f7d8d5 301 Pfam PF03466 LysR substrate binding domain 90 293 8.5E-38 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_1c26310 fbd45e8e048be570bda50bce88bd008b 391 ProSitePatterns PS00737 Thiolases signature 2. 337 353 - T 12-10-2018 IPR020613 Thiolase, conserved site GO:0016747 VAPA_1c26310 fbd45e8e048be570bda50bce88bd008b 391 SUPERFAMILY SSF53901 269 390 1.75E-41 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 VAPA_1c26310 fbd45e8e048be570bda50bce88bd008b 391 Pfam PF02803 Thiolase, C-terminal domain 268 389 9.3E-43 T 12-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 VAPA_1c26310 fbd45e8e048be570bda50bce88bd008b 391 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 86 104 - T 12-10-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0016747 VAPA_1c26310 fbd45e8e048be570bda50bce88bd008b 391 Gene3D G3DSA:3.40.47.10 6 274 2.1E-137 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 VAPA_1c26310 fbd45e8e048be570bda50bce88bd008b 391 SUPERFAMILY SSF53901 1 265 6.92E-67 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 VAPA_1c26310 fbd45e8e048be570bda50bce88bd008b 391 PIRSF PIRSF000429 1 391 9.6E-114 T 12-10-2018 IPR002155 Thiolase GO:0016747 VAPA_1c26310 fbd45e8e048be570bda50bce88bd008b 391 Pfam PF00108 Thiolase, N-terminal domain 5 260 3.1E-57 T 12-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 VAPA_1c26310 fbd45e8e048be570bda50bce88bd008b 391 Gene3D G3DSA:3.40.47.10 126 385 2.1E-137 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 VAPA_1c26310 fbd45e8e048be570bda50bce88bd008b 391 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 389 1.0E-123 T 12-10-2018 IPR002155 Thiolase GO:0016747 VAPA_2c07450 b20a482a09650d7d59350a581f2d3560 157 Pfam PF01527 Transposase 52 125 1.0E-6 T 12-10-2018 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 VAPA_2c05570 b20a482a09650d7d59350a581f2d3560 157 Pfam PF01527 Transposase 52 125 1.0E-6 T 12-10-2018 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 VAPA_2c13080 b20a482a09650d7d59350a581f2d3560 157 Pfam PF01527 Transposase 52 125 1.0E-6 T 12-10-2018 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 VAPA_1c28380 3bfc44df7b1c897f6e816d2603652693 448 Hamap MF_01105 Amino-acid acetyltransferase [argA]. 1 448 218.593 T 12-10-2018 IPR010167 Amino-acid N-acetyltransferase GO:0004042|GO:0005737|GO:0006526 KEGG: 00220+2.3.1.1|MetaCyc: PWY-5154 VAPA_1c28380 3bfc44df7b1c897f6e816d2603652693 448 PIRSF PIRSF000423 2 448 2.6E-179 T 12-10-2018 IPR010167 Amino-acid N-acetyltransferase GO:0004042|GO:0005737|GO:0006526 KEGG: 00220+2.3.1.1|MetaCyc: PWY-5154 VAPA_1c28380 3bfc44df7b1c897f6e816d2603652693 448 Gene3D G3DSA:3.40.1160.10 7 300 1.3E-81 T 12-10-2018 IPR036393 Acetylglutamate kinase-like superfamily VAPA_1c28380 3bfc44df7b1c897f6e816d2603652693 448 Pfam PF00696 Amino acid kinase family 26 217 4.2E-24 T 12-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 VAPA_1c28380 3bfc44df7b1c897f6e816d2603652693 448 Pfam PF00583 Acetyltransferase (GNAT) family 320 419 3.8E-9 T 12-10-2018 IPR000182 GNAT domain VAPA_1c28380 3bfc44df7b1c897f6e816d2603652693 448 SUPERFAMILY SSF53633 5 299 2.51E-58 T 12-10-2018 IPR036393 Acetylglutamate kinase-like superfamily VAPA_1c28380 3bfc44df7b1c897f6e816d2603652693 448 Gene3D G3DSA:3.40.630.30 301 448 7.1E-37 T 12-10-2018 VAPA_1c28380 3bfc44df7b1c897f6e816d2603652693 448 TIGRFAM TIGR01890 N-Ac-Glu-synth: amino-acid N-acetyltransferase 9 447 1.0E-181 T 12-10-2018 IPR010167 Amino-acid N-acetyltransferase GO:0004042|GO:0005737|GO:0006526 KEGG: 00220+2.3.1.1|MetaCyc: PWY-5154 VAPA_1c28380 3bfc44df7b1c897f6e816d2603652693 448 SUPERFAMILY SSF55729 304 424 1.45E-18 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase VAPA_1c34710 2310b37ec129ebbdc0f8db740e4df034 317 SUPERFAMILY SSF52768 3 316 1.49E-102 T 12-10-2018 IPR023696 Ureohydrolase domain superfamily VAPA_1c34710 2310b37ec129ebbdc0f8db740e4df034 317 Gene3D G3DSA:3.40.800.20 1 317 3.0E-120 T 12-10-2018 IPR037138 Histone deacetylase domain superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 VAPA_1c34710 2310b37ec129ebbdc0f8db740e4df034 317 PRINTS PR01270 Histone deacetylase superfamily signature 166 181 4.3E-17 T 12-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 VAPA_1c34710 2310b37ec129ebbdc0f8db740e4df034 317 PRINTS PR01270 Histone deacetylase superfamily signature 132 155 4.3E-17 T 12-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 VAPA_1c34710 2310b37ec129ebbdc0f8db740e4df034 317 PRINTS PR01270 Histone deacetylase superfamily signature 244 254 4.3E-17 T 12-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 VAPA_1c34710 2310b37ec129ebbdc0f8db740e4df034 317 Pfam PF00850 Histone deacetylase domain 21 314 2.2E-82 T 12-10-2018 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 VAPA_1c16020 d1d88e252be4c7d45608738e8c26d615 258 SUPERFAMILY SSF51735 7 257 4.24E-79 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c16020 d1d88e252be4c7d45608738e8c26d615 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 6.9E-41 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c16020 d1d88e252be4c7d45608738e8c26d615 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 6.9E-41 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c16020 d1d88e252be4c7d45608738e8c26d615 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 220 240 6.9E-41 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c16020 d1d88e252be4c7d45608738e8c26d615 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 6.9E-41 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c16020 d1d88e252be4c7d45608738e8c26d615 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 6.9E-41 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c16020 d1d88e252be4c7d45608738e8c26d615 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 6.9E-41 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c16020 d1d88e252be4c7d45608738e8c26d615 258 Gene3D G3DSA:3.40.50.720 1 258 7.9E-82 T 12-10-2018 VAPA_1c16020 d1d88e252be4c7d45608738e8c26d615 258 Pfam PF00106 short chain dehydrogenase 10 196 2.0E-61 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c16020 d1d88e252be4c7d45608738e8c26d615 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 6.6E-13 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c16020 d1d88e252be4c7d45608738e8c26d615 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 6.6E-13 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c16020 d1d88e252be4c7d45608738e8c26d615 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 6.6E-13 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c16020 d1d88e252be4c7d45608738e8c26d615 258 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 9 186 0.003 T 12-10-2018 VAPA_1c16020 d1d88e252be4c7d45608738e8c26d615 258 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 142 170 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 VAPA_1c32610 d675b13c632ee1300eb563655d5a8733 418 Gene3D G3DSA:3.30.9.10 134 359 3.1E-57 T 12-10-2018 VAPA_1c32610 d675b13c632ee1300eb563655d5a8733 418 Hamap MF_01202 D-amino acid dehydrogenase [dadA]. 1 411 48.787 T 12-10-2018 IPR023080 D-amino acid dehydrogenase DadA GO:0008718|GO:0019478|GO:0055114 VAPA_1c32610 d675b13c632ee1300eb563655d5a8733 418 Pfam PF01266 FAD dependent oxidoreductase 3 398 5.2E-75 T 12-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 VAPA_1c32610 d675b13c632ee1300eb563655d5a8733 418 SUPERFAMILY SSF54373 270 360 7.98E-18 T 12-10-2018 VAPA_1c32610 d675b13c632ee1300eb563655d5a8733 418 SUPERFAMILY SSF51905 1 416 5.05E-57 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c32610 d675b13c632ee1300eb563655d5a8733 418 Gene3D G3DSA:3.50.50.60 1 73 6.3E-13 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c32610 d675b13c632ee1300eb563655d5a8733 418 Gene3D G3DSA:3.50.50.60 104 399 3.1E-57 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c01160 628c9379922ba2c31914dccd623af4c9 258 SUPERFAMILY SSF56529 14 258 4.97E-42 T 12-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 VAPA_1c01160 628c9379922ba2c31914dccd623af4c9 258 Gene3D G3DSA:3.90.850.10 13 258 2.5E-59 T 12-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 VAPA_1c21990 5cc234b169d6ec9411f857dd03139335 317 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 113 285 2.4E-46 T 12-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 VAPA_1c21990 5cc234b169d6ec9411f857dd03139335 317 SUPERFAMILY SSF52283 8 139 1.66E-32 T 12-10-2018 VAPA_1c21990 5cc234b169d6ec9411f857dd03139335 317 Gene3D G3DSA:3.40.50.720 105 288 1.1E-114 T 12-10-2018 VAPA_1c21990 5cc234b169d6ec9411f857dd03139335 317 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 38 316 8.7E-24 T 12-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 VAPA_1c21990 5cc234b169d6ec9411f857dd03139335 317 SUPERFAMILY SSF51735 107 286 1.48E-48 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c21990 5cc234b169d6ec9411f857dd03139335 317 Gene3D G3DSA:3.40.50.720 15 312 1.1E-114 T 12-10-2018 VAPA_1c37710 afcdeab3f51d540ba928ecabca700ea9 93 SUPERFAMILY SSF54292 2 88 2.1E-27 T 12-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 VAPA_1c37710 afcdeab3f51d540ba928ecabca700ea9 93 Gene3D G3DSA:3.10.20.30 1 92 1.9E-24 T 12-10-2018 IPR012675 Beta-grasp domain superfamily VAPA_1c37710 afcdeab3f51d540ba928ecabca700ea9 93 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 6 77 3.3E-13 T 12-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 VAPA_1c44050 9fbfe4d5ba78c9c042f24b6d6d11907b 200 SUPERFAMILY SSF69737 88 148 9.16E-18 T 12-10-2018 IPR036675 UreE, C-terminal domain superfamily GO:0016151|GO:0019627|GO:0065003 VAPA_1c44050 9fbfe4d5ba78c9c042f24b6d6d11907b 200 Pfam PF05194 UreE urease accessory protein, C-terminal domain 78 166 7.5E-30 T 12-10-2018 IPR007864 Urease accessory protein UreE, C-terminal domain GO:0016151|GO:0019627|GO:0065003 VAPA_1c44050 9fbfe4d5ba78c9c042f24b6d6d11907b 200 Gene3D G3DSA:2.60.260.20 2 76 1.5E-19 T 12-10-2018 VAPA_1c44050 9fbfe4d5ba78c9c042f24b6d6d11907b 200 Hamap MF_00822 Urease accessory protein UreE [ureE]. 2 149 22.624 T 12-10-2018 IPR012406 Urease accessory protein UreE GO:0005737|GO:0006457|GO:0016151|GO:0018307 VAPA_1c44050 9fbfe4d5ba78c9c042f24b6d6d11907b 200 Pfam PF02814 UreE urease accessory protein, N-terminal domain 13 71 7.2E-19 T 12-10-2018 IPR004029 UreE urease accessory, N-terminal VAPA_1c44050 9fbfe4d5ba78c9c042f24b6d6d11907b 200 PIRSF PIRSF036402 173 200 2100.0 T 12-10-2018 IPR012406 Urease accessory protein UreE GO:0005737|GO:0006457|GO:0016151|GO:0018307 VAPA_1c44050 9fbfe4d5ba78c9c042f24b6d6d11907b 200 PIRSF PIRSF036402 7 168 3.5E-39 T 12-10-2018 IPR012406 Urease accessory protein UreE GO:0005737|GO:0006457|GO:0016151|GO:0018307 VAPA_1c44050 9fbfe4d5ba78c9c042f24b6d6d11907b 200 SUPERFAMILY SSF69287 19 77 2.22E-15 T 12-10-2018 IPR036118 UreE urease accessory, N-terminal domain superfamily VAPA_1c44050 9fbfe4d5ba78c9c042f24b6d6d11907b 200 Gene3D G3DSA:3.30.70.790 83 153 1.4E-24 T 12-10-2018 IPR036675 UreE, C-terminal domain superfamily GO:0016151|GO:0019627|GO:0065003 VAPA_1c44050 9fbfe4d5ba78c9c042f24b6d6d11907b 200 SMART SM00988 7 71 1.5E-16 T 12-10-2018 IPR004029 UreE urease accessory, N-terminal VAPA_1c51230 133fb3687a500fe02c0fb703b3f7230b 276 Gene3D G3DSA:1.10.10.60 161 264 3.3E-17 T 12-10-2018 VAPA_1c51230 133fb3687a500fe02c0fb703b3f7230b 276 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 214 255 - T 12-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 VAPA_1c51230 133fb3687a500fe02c0fb703b3f7230b 276 Pfam PF12833 Helix-turn-helix domain 184 259 3.0E-14 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 VAPA_1c51230 133fb3687a500fe02c0fb703b3f7230b 276 SMART SM00342 177 259 3.1E-12 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 VAPA_1c51230 133fb3687a500fe02c0fb703b3f7230b 276 SUPERFAMILY SSF46689 160 210 9.86E-7 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 VAPA_2c12430 bf6f2417ee480a1d7d6a658baea1362b 163 SUPERFAMILY SSF53927 3 114 1.95E-36 T 12-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 VAPA_2c12430 bf6f2417ee480a1d7d6a658baea1362b 163 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 3 101 5.7E-22 T 12-10-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain VAPA_2c12430 bf6f2417ee480a1d7d6a658baea1362b 163 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 53 90 - T 12-10-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 VAPA_2c12430 bf6f2417ee480a1d7d6a658baea1362b 163 Gene3D G3DSA:3.40.140.10 2 163 2.8E-42 T 12-10-2018 VAPA_1c17600 6686c9fa6d1b28228c2072cae5546485 112 Pfam PF06127 Protein of unknown function (DUF962) 16 109 3.8E-35 T 12-10-2018 IPR009305 Protein of unknown function DUF962 VAPA_1c03160 b74ba5de93fac56d09f6c4a4058d92f7 240 SMART SM00862 159 235 1.2E-22 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 VAPA_1c03160 b74ba5de93fac56d09f6c4a4058d92f7 240 SUPERFAMILY SSF46894 136 236 1.81E-27 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 VAPA_1c03160 b74ba5de93fac56d09f6c4a4058d92f7 240 SMART SM00448 7 121 1.7E-42 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_1c03160 b74ba5de93fac56d09f6c4a4058d92f7 240 Pfam PF00486 Transcriptional regulatory protein, C terminal 163 235 1.3E-21 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 VAPA_1c03160 b74ba5de93fac56d09f6c4a4058d92f7 240 SUPERFAMILY SSF52172 4 132 2.42E-40 T 12-10-2018 IPR011006 CheY-like superfamily VAPA_1c03160 b74ba5de93fac56d09f6c4a4058d92f7 240 Pfam PF00072 Response regulator receiver domain 10 122 2.3E-26 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_1c03160 b74ba5de93fac56d09f6c4a4058d92f7 240 Gene3D G3DSA:3.40.50.2300 1 128 1.0E-34 T 12-10-2018 VAPA_1c03160 b74ba5de93fac56d09f6c4a4058d92f7 240 Gene3D G3DSA:1.10.10.10 129 240 2.0E-35 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c36820 e79bb43e664b61a95ebfbab35673146e 304 Gene3D G3DSA:1.10.3130.10 1 66 1.5E-21 T 12-10-2018 VAPA_1c36820 e79bb43e664b61a95ebfbab35673146e 304 Gene3D G3DSA:2.160.10.10 67 188 6.0E-33 T 12-10-2018 VAPA_1c36820 e79bb43e664b61a95ebfbab35673146e 304 Pfam PF06426 Serine acetyltransferase, N-terminal 3 35 8.2E-5 T 12-10-2018 IPR010493 Serine acetyltransferase, N-terminal GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|KEGG: 00999+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274|MetaCyc: PWY-7870 VAPA_1c36820 e79bb43e664b61a95ebfbab35673146e 304 TIGRFAM TIGR01172 cysE: serine O-acetyltransferase 6 167 1.0E-69 T 12-10-2018 IPR005881 Serine O-acetyltransferase GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|KEGG: 00999+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274|MetaCyc: PWY-7870 VAPA_1c36820 e79bb43e664b61a95ebfbab35673146e 304 SUPERFAMILY SSF51161 3 170 1.19E-51 T 12-10-2018 IPR011004 Trimeric LpxA-like superfamily VAPA_1c36820 e79bb43e664b61a95ebfbab35673146e 304 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 118 152 1.1E-5 T 12-10-2018 IPR001451 Hexapeptide repeat VAPA_1c36820 e79bb43e664b61a95ebfbab35673146e 304 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 72 108 2.2E-5 T 12-10-2018 IPR001451 Hexapeptide repeat VAPA_2c01760 221368daef749ca974c98eb680cc402b 260 SMART SM00346 2 92 5.2E-24 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 VAPA_2c01760 221368daef749ca974c98eb680cc402b 260 SUPERFAMILY SSF55781 73 250 2.19E-40 T 12-10-2018 VAPA_2c01760 221368daef749ca974c98eb680cc402b 260 Pfam PF09339 IclR helix-turn-helix domain 5 54 1.6E-14 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 VAPA_2c01760 221368daef749ca974c98eb680cc402b 260 Gene3D G3DSA:1.10.10.10 3 74 1.6E-16 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_2c01760 221368daef749ca974c98eb680cc402b 260 SUPERFAMILY SSF46785 5 75 6.25E-14 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_2c01760 221368daef749ca974c98eb680cc402b 260 Gene3D G3DSA:3.30.450.40 75 254 1.5E-44 T 12-10-2018 IPR029016 GAF-like domain superfamily VAPA_2c01760 221368daef749ca974c98eb680cc402b 260 Pfam PF01614 Bacterial transcriptional regulator 123 248 1.7E-16 T 12-10-2018 IPR014757 Transcription regulator IclR, C-terminal VAPA_1c32270 087849743f9a8c369f3f111d81f6e0e4 410 Pfam PF03069 Acetamidase/Formamidase family 7 384 1.7E-174 T 12-10-2018 IPR004304 Acetamidase/Formamidase GO:0016811 VAPA_1c32270 087849743f9a8c369f3f111d81f6e0e4 410 Gene3D G3DSA:2.60.120.580 192 281 2.4E-21 T 12-10-2018 VAPA_1c32270 087849743f9a8c369f3f111d81f6e0e4 410 Gene3D G3DSA:2.60.120.580 6 140 1.8E-14 T 12-10-2018 VAPA_1c32270 087849743f9a8c369f3f111d81f6e0e4 410 SUPERFAMILY SSF141130 15 383 2.62E-78 T 12-10-2018 VAPA_2c05730 16d6a31fd1ea341758911d71f1a5c685 144 Pfam PF13564 DoxX-like family 10 108 1.0E-10 T 12-10-2018 IPR032808 DoxX family VAPA_1c36750 b11249db5b4e0b3a402dba279de5627a 225 SMART SM00862 144 219 5.9E-24 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 VAPA_1c36750 b11249db5b4e0b3a402dba279de5627a 225 TIGRFAM TIGR01387 cztR_silR_copR: heavy metal response regulator 3 219 8.9E-99 T 12-10-2018 IPR006291 Transcriptional regulatory protein PcoR, heavy metal response GO:0003677|GO:0006355 VAPA_1c36750 b11249db5b4e0b3a402dba279de5627a 225 Gene3D G3DSA:3.40.50.2300 1 120 4.3E-41 T 12-10-2018 VAPA_1c36750 b11249db5b4e0b3a402dba279de5627a 225 SMART SM00448 1 111 3.5E-42 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_1c36750 b11249db5b4e0b3a402dba279de5627a 225 SUPERFAMILY SSF52172 1 178 6.64E-42 T 12-10-2018 IPR011006 CheY-like superfamily VAPA_1c36750 b11249db5b4e0b3a402dba279de5627a 225 Pfam PF00486 Transcriptional regulatory protein, C terminal 146 219 3.2E-25 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 VAPA_1c36750 b11249db5b4e0b3a402dba279de5627a 225 Pfam PF00072 Response regulator receiver domain 3 112 3.9E-26 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_1c36750 b11249db5b4e0b3a402dba279de5627a 225 Gene3D G3DSA:1.10.10.10 121 224 1.1E-30 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c33880 811b201d81ab96c79c5cee2aadedfa4f 420 Pfam PF07804 HipA-like C-terminal domain 173 383 2.4E-47 T 12-10-2018 IPR012893 HipA-like, C-terminal VAPA_1c33880 811b201d81ab96c79c5cee2aadedfa4f 420 Pfam PF13657 HipA N-terminal domain 40 127 1.7E-5 T 12-10-2018 IPR017508 HipA, N-terminal subdomain 1 VAPA_1c19010 fc605f97441e91649a5f38ef25d962c0 797 SUPERFAMILY SSF51621 470 796 1.07E-91 T 12-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 VAPA_1c19010 fc605f97441e91649a5f38ef25d962c0 797 Gene3D G3DSA:3.50.30.10 366 483 1.1E-40 T 12-10-2018 VAPA_1c19010 fc605f97441e91649a5f38ef25d962c0 797 Gene3D G3DSA:3.30.470.20 198 364 1.1E-56 T 12-10-2018 VAPA_1c19010 fc605f97441e91649a5f38ef25d962c0 797 TIGRFAM TIGR01418 PEP_synth: phosphoenolpyruvate synthase 11 796 0.0 T 12-10-2018 IPR006319 Phosphoenolpyruvate synthase GO:0006090|GO:0008986 KEGG: 00620+2.7.9.2|KEGG: 00680+2.7.9.2|KEGG: 00720+2.7.9.2|MetaCyc: PWY-5484|MetaCyc: PWY-6142 VAPA_1c19010 fc605f97441e91649a5f38ef25d962c0 797 SUPERFAMILY SSF56059 7 391 1.12E-105 T 12-10-2018 VAPA_1c19010 fc605f97441e91649a5f38ef25d962c0 797 PIRSF PIRSF000854 6 797 0.0 T 12-10-2018 IPR006319 Phosphoenolpyruvate synthase GO:0006090|GO:0008986 KEGG: 00620+2.7.9.2|KEGG: 00680+2.7.9.2|KEGG: 00720+2.7.9.2|MetaCyc: PWY-5484|MetaCyc: PWY-6142 VAPA_1c19010 fc605f97441e91649a5f38ef25d962c0 797 Gene3D G3DSA:3.30.1490.20 7 197 6.0E-71 T 12-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 VAPA_1c19010 fc605f97441e91649a5f38ef25d962c0 797 Pfam PF00391 PEP-utilising enzyme, mobile domain 391 462 3.8E-26 T 12-10-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 VAPA_1c19010 fc605f97441e91649a5f38ef25d962c0 797 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 480 796 4.8E-59 T 12-10-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 VAPA_1c19010 fc605f97441e91649a5f38ef25d962c0 797 Gene3D G3DSA:3.20.20.60 485 797 8.9E-98 T 12-10-2018 VAPA_1c19010 fc605f97441e91649a5f38ef25d962c0 797 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 23 352 8.9E-116 T 12-10-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 VAPA_1c19010 fc605f97441e91649a5f38ef25d962c0 797 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 421 432 - T 12-10-2018 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 VAPA_1c19010 fc605f97441e91649a5f38ef25d962c0 797 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 701 719 - T 12-10-2018 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 VAPA_1c19010 fc605f97441e91649a5f38ef25d962c0 797 SUPERFAMILY SSF52009 356 474 2.35E-34 T 12-10-2018 IPR036637 Phosphohistidine domain superfamily GO:0016310|GO:0016772 VAPA_2c00440 ebe9e4ec62a129131a5386426deca8d1 396 Pfam PF02515 CoA-transferase family III 10 373 6.0E-120 T 12-10-2018 IPR003673 CoA-transferase family III GO:0003824 VAPA_2c00440 ebe9e4ec62a129131a5386426deca8d1 396 Gene3D G3DSA:3.40.50.10540 10 390 4.3E-125 T 12-10-2018 IPR023606 CoA-transferase family III domain superfamily VAPA_2c00440 ebe9e4ec62a129131a5386426deca8d1 396 SUPERFAMILY SSF89796 9 395 1.44E-129 T 12-10-2018 IPR023606 CoA-transferase family III domain superfamily VAPA_2c00440 ebe9e4ec62a129131a5386426deca8d1 396 Gene3D G3DSA:3.30.1540.10 228 325 4.3E-125 T 12-10-2018 VAPA_2c03080 5e5bd3dcb9fccd27ab82380340489f62 325 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 48 320 5.0E-78 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_2c03080 5e5bd3dcb9fccd27ab82380340489f62 325 Gene3D G3DSA:3.40.190.150 29 315 4.5E-101 T 12-10-2018 VAPA_2c03080 5e5bd3dcb9fccd27ab82380340489f62 325 Gene3D G3DSA:3.40.190.10 127 250 4.5E-101 T 12-10-2018 VAPA_2c03080 5e5bd3dcb9fccd27ab82380340489f62 325 SUPERFAMILY SSF53850 81 273 5.21E-11 T 12-10-2018 VAPA_2c03080 5e5bd3dcb9fccd27ab82380340489f62 325 PIRSF PIRSF017082 1 325 1.6E-76 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c12750 b4841f54d39a4e5b20a649eabc3c24d3 313 SUPERFAMILY SSF161098 90 297 2.75E-22 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c12750 b4841f54d39a4e5b20a649eabc3c24d3 313 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 312 6.3E-45 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 VAPA_1c12750 b4841f54d39a4e5b20a649eabc3c24d3 313 Gene3D G3DSA:1.10.3720.10 85 308 6.2E-28 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c41240 986f48cf3c6c078e054dfe208387fd10 196 SUPERFAMILY SSF51182 12 189 7.74E-39 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily VAPA_1c41240 986f48cf3c6c078e054dfe208387fd10 196 Gene3D G3DSA:2.60.120.10 50 193 5.0E-26 T 12-10-2018 IPR014710 RmlC-like jelly roll fold VAPA_1c04200 37e825546c5adda55efb394349eab696 234 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 27 232 4.4E-47 T 12-10-2018 IPR011234 Fumarylacetoacetase-like, C-terminal GO:0003824 VAPA_1c04200 37e825546c5adda55efb394349eab696 234 Gene3D G3DSA:3.90.850.10 2 234 1.3E-78 T 12-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 VAPA_1c04200 37e825546c5adda55efb394349eab696 234 SUPERFAMILY SSF56529 21 233 8.5E-65 T 12-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 VAPA_1c20260 f169e5bfba6f73f20692b4eca64e9237 302 Pfam PF02668 Taurine catabolism dioxygenase TauD, TfdA family 23 294 1.6E-58 T 12-10-2018 IPR003819 TauD/TfdA-like domain GO:0016491|GO:0055114 Reactome: R-HSA-71262 VAPA_1c20260 f169e5bfba6f73f20692b4eca64e9237 302 Gene3D G3DSA:3.60.130.10 20 302 5.1E-79 T 12-10-2018 VAPA_1c20260 f169e5bfba6f73f20692b4eca64e9237 302 SUPERFAMILY SSF51197 21 301 3.39E-83 T 12-10-2018 VAPA_1c05000 183ce77a6c7865d87d7a78690cc616f5 357 SUPERFAMILY SSF51735 5 178 7.35E-15 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c05000 183ce77a6c7865d87d7a78690cc616f5 357 Gene3D G3DSA:3.40.50.720 4 194 1.5E-31 T 12-10-2018 VAPA_1c05000 183ce77a6c7865d87d7a78690cc616f5 357 Gene3D G3DSA:1.10.1040.10 195 346 2.3E-38 T 12-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 VAPA_1c05000 183ce77a6c7865d87d7a78690cc616f5 357 SUPERFAMILY SSF48179 187 356 3.16E-36 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 VAPA_1c05000 183ce77a6c7865d87d7a78690cc616f5 357 Pfam PF02558 Ketopantoate reductase PanE/ApbA 9 152 8.5E-7 T 12-10-2018 IPR013332 Ketopantoate reductase, N-terminal domain VAPA_1c05000 183ce77a6c7865d87d7a78690cc616f5 357 Pfam PF02317 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain 186 326 9.3E-32 T 12-10-2018 IPR003421 Opine dehydrogenase GO:0016491|GO:0050662|GO:0055114 VAPA_1c37930 ed831c18bacf10c5adda382bc5611911 323 SUPERFAMILY SSF53187 7 319 9.43E-56 T 12-10-2018 VAPA_1c37930 ed831c18bacf10c5adda382bc5611911 323 Gene3D G3DSA:3.40.630.10 16 320 5.9E-52 T 12-10-2018 VAPA_1c37930 ed831c18bacf10c5adda382bc5611911 323 Pfam PF04952 Succinylglutamate desuccinylase / Aspartoacylase family 36 183 9.4E-15 T 12-10-2018 IPR007036 Succinylglutamate desuccinylase/aspartoacylase GO:0016788 VAPA_1c27030 f5ca998199f62f8635b53712c783a8d7 126 SUPERFAMILY SSF51182 31 120 2.91E-9 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily VAPA_1c27030 f5ca998199f62f8635b53712c783a8d7 126 Gene3D G3DSA:2.60.120.10 3 125 1.7E-5 T 12-10-2018 IPR014710 RmlC-like jelly roll fold VAPA_1c18480 79e9fb44b3c56ff2063d2026fae6e388 411 Pfam PF07690 Major Facilitator Superfamily 21 362 4.3E-45 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 VAPA_1c18480 79e9fb44b3c56ff2063d2026fae6e388 411 TIGRFAM TIGR00710 efflux_Bcr_CflA: drug resistance transporter, Bcr/CflA subfamily 14 392 2.2E-81 T 12-10-2018 IPR004812 Drug resistance transporter Bcr/CmlA subfamily GO:0006855|GO:0015238|GO:0016021 VAPA_1c18480 79e9fb44b3c56ff2063d2026fae6e388 411 SUPERFAMILY SSF103473 6 402 1.11E-62 T 12-10-2018 IPR036259 MFS transporter superfamily VAPA_1c18480 79e9fb44b3c56ff2063d2026fae6e388 411 Gene3D G3DSA:1.20.1720.10 16 396 2.5E-96 T 12-10-2018 VAPA_1c53880 ed2be081a9dfc8ac2f3913ed388a74da 191 Gene3D G3DSA:2.20.70.110 152 187 3.7E-9 T 12-10-2018 VAPA_1c53880 ed2be081a9dfc8ac2f3913ed388a74da 191 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 103 135 0.0012 T 12-10-2018 IPR001451 Hexapeptide repeat VAPA_1c53880 ed2be081a9dfc8ac2f3913ed388a74da 191 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 31 64 2.1E-9 T 12-10-2018 IPR001451 Hexapeptide repeat VAPA_1c53880 ed2be081a9dfc8ac2f3913ed388a74da 191 Gene3D G3DSA:2.160.10.10 1 150 4.1E-44 T 12-10-2018 VAPA_1c53880 ed2be081a9dfc8ac2f3913ed388a74da 191 SUPERFAMILY SSF51161 3 179 9.03E-43 T 12-10-2018 IPR011004 Trimeric LpxA-like superfamily VAPA_1c32220 eb49595056425ed94c37c4e37e6dbf65 227 Gene3D G3DSA:3.40.50.150 40 215 1.0E-21 T 12-10-2018 VAPA_1c32220 eb49595056425ed94c37c4e37e6dbf65 227 SUPERFAMILY SSF53335 51 203 1.54E-11 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase VAPA_1c49020 f03b60cf4a8c23895f33c417b07e70c0 356 PRINTS PR00139 Asparaginase/glutaminase family signature 32 43 1.0E-22 T 12-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 VAPA_1c49020 f03b60cf4a8c23895f33c417b07e70c0 356 PRINTS PR00139 Asparaginase/glutaminase family signature 290 308 1.0E-22 T 12-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 VAPA_1c49020 f03b60cf4a8c23895f33c417b07e70c0 356 PRINTS PR00139 Asparaginase/glutaminase family signature 112 130 1.0E-22 T 12-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 VAPA_1c49020 f03b60cf4a8c23895f33c417b07e70c0 356 Gene3D G3DSA:3.40.50.1170 29 242 8.1E-80 T 12-10-2018 IPR037152 L-asparaginase, N-terminal domain superfamily Reactome: R-HSA-70614 VAPA_1c49020 f03b60cf4a8c23895f33c417b07e70c0 356 PIRSF PIRSF001220 26 356 3.4E-83 T 12-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 VAPA_1c49020 f03b60cf4a8c23895f33c417b07e70c0 356 ProSitePatterns PS00144 Asparaginase / glutaminase active site signature 1. 34 42 - T 12-10-2018 IPR020827 Asparaginase/glutaminase, active site 1 GO:0006520 VAPA_1c49020 f03b60cf4a8c23895f33c417b07e70c0 356 SMART SM00870 31 350 1.6E-119 T 12-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 VAPA_1c49020 f03b60cf4a8c23895f33c417b07e70c0 356 Gene3D G3DSA:3.40.50.40 243 356 5.2E-35 T 12-10-2018 IPR027473 L-asparaginase, C-terminal Reactome: R-HSA-70614 VAPA_1c49020 f03b60cf4a8c23895f33c417b07e70c0 356 ProSitePatterns PS00917 Asparaginase / glutaminase active site signature 2. 113 123 - T 12-10-2018 IPR027475 Asparaginase/glutaminase, active site 2 Reactome: R-HSA-70614 VAPA_1c49020 f03b60cf4a8c23895f33c417b07e70c0 356 SUPERFAMILY SSF53774 29 355 4.84E-93 T 12-10-2018 IPR036152 Asparaginase/glutaminase-like superfamily Reactome: R-HSA-70614 VAPA_1c49020 f03b60cf4a8c23895f33c417b07e70c0 356 TIGRFAM TIGR00520 asnASE_II: L-asparaginase, type II 15 356 2.8E-115 T 12-10-2018 IPR004550 L-asparaginase, type II GO:0004067|GO:0006528 VAPA_1c49020 f03b60cf4a8c23895f33c417b07e70c0 356 PIRSF PIRSF500176 28 356 1.2E-74 T 12-10-2018 VAPA_1c49020 f03b60cf4a8c23895f33c417b07e70c0 356 Pfam PF00710 Asparaginase, N-terminal 31 221 1.1E-50 T 12-10-2018 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 VAPA_1c22510 2411dd5a938705c7c9cf54b25555db4d 564 Gene3D G3DSA:3.30.9.50 74 299 2.1E-100 T 12-10-2018 VAPA_1c22510 2411dd5a938705c7c9cf54b25555db4d 564 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 353 369 2.7E-38 T 12-10-2018 VAPA_1c22510 2411dd5a938705c7c9cf54b25555db4d 564 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 302 317 2.7E-38 T 12-10-2018 VAPA_1c22510 2411dd5a938705c7c9cf54b25555db4d 564 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 317 333 2.7E-38 T 12-10-2018 VAPA_1c22510 2411dd5a938705c7c9cf54b25555db4d 564 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 8 30 2.7E-38 T 12-10-2018 VAPA_1c22510 2411dd5a938705c7c9cf54b25555db4d 564 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 335 353 2.7E-38 T 12-10-2018 VAPA_1c22510 2411dd5a938705c7c9cf54b25555db4d 564 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 176 191 2.7E-38 T 12-10-2018 VAPA_1c22510 2411dd5a938705c7c9cf54b25555db4d 564 Pfam PF01494 FAD binding domain 6 368 8.2E-69 T 12-10-2018 IPR002938 FAD-binding domain GO:0071949 VAPA_1c22510 2411dd5a938705c7c9cf54b25555db4d 564 SUPERFAMILY SSF51905 6 376 8.25E-50 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c22510 2411dd5a938705c7c9cf54b25555db4d 564 Gene3D G3DSA:3.40.30.120 420 547 2.2E-29 T 12-10-2018 VAPA_1c22510 2411dd5a938705c7c9cf54b25555db4d 564 Gene3D G3DSA:3.50.50.60 7 362 2.1E-100 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c34040 49859d25fcc737c078fbd36a72aaddbd 323 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 31 309 2.6E-91 T 12-10-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0030288|GO:0055085 VAPA_1c34040 49859d25fcc737c078fbd36a72aaddbd 323 TIGRFAM TIGR00787 dctP: TRAP transporter solute receptor, DctP family 31 282 1.6E-79 T 12-10-2018 IPR004682 TRAP transporter solute receptor, DctP family GO:0030288|GO:0055085 VAPA_1c34040 49859d25fcc737c078fbd36a72aaddbd 323 Gene3D G3DSA:3.40.190.170 23 323 5.2E-130 T 12-10-2018 IPR038404 TRAP transporter solute receptor DctP superfamily VAPA_1c34040 49859d25fcc737c078fbd36a72aaddbd 323 PIRSF PIRSF006470 1 323 1.8E-104 T 12-10-2018 IPR004682 TRAP transporter solute receptor, DctP family GO:0030288|GO:0055085 VAPA_2c03090 4d68b0cb6b6a2c405ff85fcb4ced46b0 308 SUPERFAMILY SSF52283 5 132 1.32E-22 T 12-10-2018 VAPA_2c03090 4d68b0cb6b6a2c405ff85fcb4ced46b0 308 Gene3D G3DSA:3.40.50.720 98 277 8.8E-89 T 12-10-2018 VAPA_2c03090 4d68b0cb6b6a2c405ff85fcb4ced46b0 308 SUPERFAMILY SSF51735 98 280 6.84E-52 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_2c03090 4d68b0cb6b6a2c405ff85fcb4ced46b0 308 Gene3D G3DSA:3.40.50.720 10 302 8.8E-89 T 12-10-2018 VAPA_2c03090 4d68b0cb6b6a2c405ff85fcb4ced46b0 308 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 10 308 4.4E-21 T 12-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 VAPA_2c03090 4d68b0cb6b6a2c405ff85fcb4ced46b0 308 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 218 234 - T 12-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site VAPA_2c03090 4d68b0cb6b6a2c405ff85fcb4ced46b0 308 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 107 279 3.7E-53 T 12-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 VAPA_2c03090 4d68b0cb6b6a2c405ff85fcb4ced46b0 308 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 189 211 - T 12-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site VAPA_1c03680 76ee0ecc4f20c4af3541f7603c7aaed7 384 SUPERFAMILY SSF51905 9 372 2.24E-50 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c03680 76ee0ecc4f20c4af3541f7603c7aaed7 384 Pfam PF01266 FAD dependent oxidoreductase 10 352 7.1E-61 T 12-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 VAPA_1c03680 76ee0ecc4f20c4af3541f7603c7aaed7 384 Gene3D G3DSA:3.30.9.10 89 315 4.7E-91 T 12-10-2018 VAPA_1c03680 76ee0ecc4f20c4af3541f7603c7aaed7 384 Gene3D G3DSA:3.50.50.60 10 359 4.7E-91 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c03680 76ee0ecc4f20c4af3541f7603c7aaed7 384 SUPERFAMILY SSF54373 230 308 1.28E-6 T 12-10-2018 VAPA_2c08450 10a894f9022062e3ccbac7f208dc2936 476 SUPERFAMILY SSF53720 6 471 1.57E-139 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 VAPA_2c08450 10a894f9022062e3ccbac7f208dc2936 476 Gene3D G3DSA:3.40.605.10 22 467 7.7E-150 T 12-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 VAPA_2c08450 10a894f9022062e3ccbac7f208dc2936 476 Gene3D G3DSA:3.40.309.10 251 442 7.7E-150 T 12-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 VAPA_2c08450 10a894f9022062e3ccbac7f208dc2936 476 Pfam PF00171 Aldehyde dehydrogenase family 17 469 1.1E-144 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 VAPA_2c08450 10a894f9022062e3ccbac7f208dc2936 476 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 271 282 - T 12-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 VAPA_1c12570 57fddd57ef02bfd806fba3eabec5269d 206 Gene3D G3DSA:2.40.360.10 21 193 1.2E-11 T 12-10-2018 IPR023373 YmcC-like superfamily VAPA_1c12570 57fddd57ef02bfd806fba3eabec5269d 206 Pfam PF11102 Group 4 capsule polysaccharide lipoprotein gfcB, YjbF 23 183 1.3E-17 T 12-10-2018 IPR021308 Group 4 capsule polysaccharide formation lipoprotein GfcB VAPA_1c12570 57fddd57ef02bfd806fba3eabec5269d 206 SUPERFAMILY SSF159270 1 195 1.23E-39 T 12-10-2018 IPR023373 YmcC-like superfamily VAPA_2c07600 b50dabd2e3d367d11ac1a4b738e51db5 394 Gene3D G3DSA:1.10.490.10 1 143 1.3E-55 T 12-10-2018 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 VAPA_2c07600 b50dabd2e3d367d11ac1a4b738e51db5 394 Pfam PF00970 Oxidoreductase FAD-binding domain 156 251 2.2E-10 T 12-10-2018 IPR008333 Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain Reactome: R-HSA-1237044 VAPA_2c07600 b50dabd2e3d367d11ac1a4b738e51db5 394 Pfam PF00175 Oxidoreductase NAD-binding domain 265 367 1.8E-14 T 12-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 VAPA_2c07600 b50dabd2e3d367d11ac1a4b738e51db5 394 Gene3D G3DSA:2.40.30.10 150 252 7.5E-33 T 12-10-2018 VAPA_2c07600 b50dabd2e3d367d11ac1a4b738e51db5 394 SUPERFAMILY SSF52343 260 388 1.96E-32 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain VAPA_2c07600 b50dabd2e3d367d11ac1a4b738e51db5 394 SUPERFAMILY SSF63380 149 251 6.99E-29 T 12-10-2018 IPR017938 Riboflavin synthase-like beta-barrel VAPA_2c07600 b50dabd2e3d367d11ac1a4b738e51db5 394 SUPERFAMILY SSF46458 1 143 1.31E-40 T 12-10-2018 IPR009050 Globin-like superfamily VAPA_2c07600 b50dabd2e3d367d11ac1a4b738e51db5 394 Gene3D G3DSA:3.40.50.80 256 391 3.2E-29 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain VAPA_2c07600 b50dabd2e3d367d11ac1a4b738e51db5 394 PRINTS PR00410 Phenol hydroxylase reductase family signature 184 196 1.8E-6 T 12-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 VAPA_2c07600 b50dabd2e3d367d11ac1a4b738e51db5 394 PRINTS PR00410 Phenol hydroxylase reductase family signature 264 283 1.8E-6 T 12-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 VAPA_2c07600 b50dabd2e3d367d11ac1a4b738e51db5 394 PRINTS PR00410 Phenol hydroxylase reductase family signature 354 362 1.8E-6 T 12-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 VAPA_2c07600 b50dabd2e3d367d11ac1a4b738e51db5 394 Pfam PF00042 Globin 6 102 1.9E-10 T 12-10-2018 IPR000971 Globin GO:0020037 VAPA_2c02200 c5fec749494e0fa99a8ebd1f0215fad2 312 Gene3D G3DSA:3.20.20.70 3 310 1.3E-66 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 VAPA_2c02200 c5fec749494e0fa99a8ebd1f0215fad2 312 SMART SM01130 6 308 5.9E-66 T 12-10-2018 IPR002220 DapA-like GO:0016829 VAPA_2c02200 c5fec749494e0fa99a8ebd1f0215fad2 312 PIRSF PIRSF001365 3 312 1.3E-54 T 12-10-2018 IPR002220 DapA-like GO:0016829 VAPA_2c02200 c5fec749494e0fa99a8ebd1f0215fad2 312 SUPERFAMILY SSF51569 7 309 5.13E-63 T 12-10-2018 VAPA_2c02200 c5fec749494e0fa99a8ebd1f0215fad2 312 Pfam PF00701 Dihydrodipicolinate synthetase family 7 306 6.5E-35 T 12-10-2018 IPR002220 DapA-like GO:0016829 VAPA_1c39920 298d81ac2ed47070ce6898575e45b9ac 205 Gene3D G3DSA:2.60.120.10 46 188 4.2E-55 T 12-10-2018 IPR014710 RmlC-like jelly roll fold VAPA_1c39920 298d81ac2ed47070ce6898575e45b9ac 205 SUPERFAMILY SSF51182 12 195 1.91E-52 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily VAPA_1c39920 298d81ac2ed47070ce6898575e45b9ac 205 Pfam PF05995 Cysteine dioxygenase type I 51 164 1.2E-9 T 12-10-2018 IPR010300 Cysteine dioxygenase type I GO:0005506|GO:0016702|GO:0055114 KEGG: 00270+1.13.11.20|KEGG: 00430+1.13.11.20|MetaCyc: PWY-5331|Reactome: R-HSA-1614558 VAPA_1c39920 298d81ac2ed47070ce6898575e45b9ac 205 Gene3D G3DSA:1.20.5.440 1 45 1.3E-12 T 12-10-2018 VAPA_2c12400 d8f3435d8216d0119ecf1cfc516c49e5 234 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 130 158 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 VAPA_2c12400 d8f3435d8216d0119ecf1cfc516c49e5 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 117 133 2.6E-19 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c12400 d8f3435d8216d0119ecf1cfc516c49e5 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 143 162 2.6E-19 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c12400 d8f3435d8216d0119ecf1cfc516c49e5 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 2.6E-19 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c12400 d8f3435d8216d0119ecf1cfc516c49e5 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 69 80 2.6E-19 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c12400 d8f3435d8216d0119ecf1cfc516c49e5 234 Pfam PF00106 short chain dehydrogenase 7 182 1.3E-35 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c12400 d8f3435d8216d0119ecf1cfc516c49e5 234 SUPERFAMILY SSF51735 5 204 6.49E-49 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_2c12400 d8f3435d8216d0119ecf1cfc516c49e5 234 Gene3D G3DSA:3.40.50.720 1 226 2.3E-51 T 12-10-2018 VAPA_2c12400 d8f3435d8216d0119ecf1cfc516c49e5 234 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 143 162 2.4E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c12400 d8f3435d8216d0119ecf1cfc516c49e5 234 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 123 131 2.4E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c12400 d8f3435d8216d0119ecf1cfc516c49e5 234 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 69 80 2.4E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c13860 75ce06620995844673ba550569aefef4 262 Gene3D G3DSA:1.10.580.10 44 239 1.4E-22 T 12-10-2018 IPR016142 Citrate synthase-like, large alpha subdomain Reactome: R-HSA-1268020|Reactome: R-HSA-71403 VAPA_1c13860 75ce06620995844673ba550569aefef4 262 Gene3D G3DSA:1.10.230.10 107 213 1.4E-22 T 12-10-2018 IPR016143 Citrate synthase-like, small alpha subdomain VAPA_1c13860 75ce06620995844673ba550569aefef4 262 SUPERFAMILY SSF48256 9 246 6.8E-44 T 12-10-2018 IPR036969 Citrate synthase superfamily GO:0046912 VAPA_1c13860 75ce06620995844673ba550569aefef4 262 Pfam PF00285 Citrate synthase, C-terminal domain 45 242 1.2E-21 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 VAPA_1c31140 49529ac26f10490175c214e03f8a03cb 291 SUPERFAMILY SSF53300 73 195 2.67E-7 T 12-10-2018 IPR036465 von Willebrand factor A-like domain superfamily VAPA_1c31140 49529ac26f10490175c214e03f8a03cb 291 Pfam PF01882 Protein of unknown function DUF58 31 117 6.6E-5 T 12-10-2018 IPR002881 Domain of unknown function DUF58 VAPA_1c19050 260f4a3ae75434fa48bd7077c725612e 93 PRINTS PR00974 Ribosomal protein S18 family signature 55 62 5.4E-15 T 12-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 VAPA_1c19050 260f4a3ae75434fa48bd7077c725612e 93 PRINTS PR00974 Ribosomal protein S18 family signature 63 77 5.4E-15 T 12-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 VAPA_1c19050 260f4a3ae75434fa48bd7077c725612e 93 PRINTS PR00974 Ribosomal protein S18 family signature 77 87 5.4E-15 T 12-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 VAPA_1c19050 260f4a3ae75434fa48bd7077c725612e 93 PRINTS PR00974 Ribosomal protein S18 family signature 45 55 5.4E-15 T 12-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 VAPA_1c19050 260f4a3ae75434fa48bd7077c725612e 93 SUPERFAMILY SSF46911 18 91 9.94E-26 T 12-10-2018 IPR036870 Ribosomal protein S18 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 VAPA_1c19050 260f4a3ae75434fa48bd7077c725612e 93 Hamap MF_00270 30S ribosomal protein S18 [rpsR]. 10 90 19.79 T 12-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 VAPA_1c19050 260f4a3ae75434fa48bd7077c725612e 93 Pfam PF01084 Ribosomal protein S18 36 84 4.0E-22 T 12-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 VAPA_1c19050 260f4a3ae75434fa48bd7077c725612e 93 ProDom PD002239 RIBOSOMAL S18 RIBONUCLEOPROTEIN 30S RRNA-BINDING RNA-BINDING CHLOROPLAST PLASTID MITOCHONDRIAL ACETYLATION 38 90 2.0E-23 T 12-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 VAPA_1c19050 260f4a3ae75434fa48bd7077c725612e 93 ProSitePatterns PS00057 Ribosomal protein S18 signature. 38 61 - T 12-10-2018 IPR018275 Ribosomal protein S18, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 VAPA_1c19050 260f4a3ae75434fa48bd7077c725612e 93 Gene3D G3DSA:4.10.640.10 6 92 6.1E-25 T 12-10-2018 IPR036870 Ribosomal protein S18 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 VAPA_1c19050 260f4a3ae75434fa48bd7077c725612e 93 TIGRFAM TIGR00165 S18: ribosomal protein bS18 22 89 2.5E-32 T 12-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 VAPA_1c41600 0d17602343695fa35aed93a5242d9c9f 527 TIGRFAM TIGR03409 urea_trans_UrtB: urea ABC transporter, permease protein UrtB 231 523 4.5E-129 T 12-10-2018 IPR017779 ABC transporter, urea permease protein UrtB, bacterial-type VAPA_1c41600 0d17602343695fa35aed93a5242d9c9f 527 Pfam PF02653 Branched-chain amino acid transport system / permease component 233 508 6.7E-49 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 VAPA_1c52220 f19102b065e9803c890fbace875331a2 324 Gene3D G3DSA:3.40.50.920 199 324 4.2E-33 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 VAPA_1c52220 f19102b065e9803c890fbace875331a2 324 Pfam PF02780 Transketolase, C-terminal domain 197 315 1.4E-28 T 12-10-2018 IPR033248 Transketolase, C-terminal domain VAPA_1c52220 f19102b065e9803c890fbace875331a2 324 SMART SM00861 10 184 5.8E-56 T 12-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain VAPA_1c52220 f19102b065e9803c890fbace875331a2 324 SUPERFAMILY SSF52518 10 190 8.03E-59 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold VAPA_1c52220 f19102b065e9803c890fbace875331a2 324 SUPERFAMILY SSF52922 194 323 9.68E-32 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 VAPA_1c52220 f19102b065e9803c890fbace875331a2 324 Gene3D G3DSA:3.40.50.970 9 198 6.2E-74 T 12-10-2018 VAPA_1c52220 f19102b065e9803c890fbace875331a2 324 Pfam PF02779 Transketolase, pyrimidine binding domain 10 181 2.5E-42 T 12-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain VAPA_1c21280 e9dac690919662614b77fbe63073fde3 157 Pfam PF00571 CBS domain 4 56 1.6E-9 T 12-10-2018 IPR000644 CBS domain VAPA_1c21280 e9dac690919662614b77fbe63073fde3 157 Pfam PF00571 CBS domain 69 117 1.8E-8 T 12-10-2018 IPR000644 CBS domain VAPA_1c21280 e9dac690919662614b77fbe63073fde3 157 SMART SM00116 75 123 0.36 T 12-10-2018 IPR000644 CBS domain VAPA_1c21280 e9dac690919662614b77fbe63073fde3 157 SMART SM00116 11 58 1.3E-9 T 12-10-2018 IPR000644 CBS domain VAPA_1c21280 e9dac690919662614b77fbe63073fde3 157 SUPERFAMILY SSF54631 3 117 7.33E-31 T 12-10-2018 VAPA_1c21280 e9dac690919662614b77fbe63073fde3 157 Gene3D G3DSA:3.10.580.10 1 124 2.9E-32 T 12-10-2018 VAPA_1c27050 1e1cc3e5888cd6c889bbf8e1849b61aa 68 Gene3D G3DSA:3.30.1660.10 1 68 8.4E-33 T 12-10-2018 IPR025543 Dodecin-like VAPA_1c27050 1e1cc3e5888cd6c889bbf8e1849b61aa 68 SUPERFAMILY SSF89807 3 68 1.09E-25 T 12-10-2018 IPR036694 Dodecin-like superfamily VAPA_1c27050 1e1cc3e5888cd6c889bbf8e1849b61aa 68 Pfam PF07311 Dodecin 5 68 2.8E-30 T 12-10-2018 IPR009923 Dodecin VAPA_1c43570 bf4df12b1962a338e31b9c9f606086cf 237 Pfam PF13144 Chaperone for flagella basal body P-ring formation 38 234 1.0E-34 T 12-10-2018 IPR017585 Flagella basal body P-ring formation protein FlgA, C-terminal VAPA_1c43570 bf4df12b1962a338e31b9c9f606086cf 237 Gene3D G3DSA:2.30.30.760 179 235 1.1E-15 T 12-10-2018 VAPA_1c43570 bf4df12b1962a338e31b9c9f606086cf 237 SMART SM00858 113 175 2.8E-6 T 12-10-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 VAPA_1c43570 bf4df12b1962a338e31b9c9f606086cf 237 TIGRFAM TIGR03170 flgA_cterm: flagella basal body P-ring formation protein FlgA 101 234 9.6E-29 T 12-10-2018 IPR017585 Flagella basal body P-ring formation protein FlgA, C-terminal VAPA_1c31570 4f8867bfc526318462ad5da0c81adef6 216 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 55 173 6.6E-8 T 12-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 VAPA_1c31570 4f8867bfc526318462ad5da0c81adef6 216 SMART SM00478 58 210 9.1E-12 T 12-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 VAPA_1c31570 4f8867bfc526318462ad5da0c81adef6 216 Gene3D G3DSA:1.10.340.30 48 157 1.8E-60 T 12-10-2018 VAPA_1c31570 4f8867bfc526318462ad5da0c81adef6 216 Gene3D G3DSA:1.10.1670.40 22 207 1.8E-60 T 12-10-2018 VAPA_1c31570 4f8867bfc526318462ad5da0c81adef6 216 SUPERFAMILY SSF48150 38 208 4.54E-39 T 12-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 VAPA_1c22580 7a0c392726f3db9c4fb43165f2be89e8 333 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 300 308 2.0E-8 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 VAPA_1c22580 7a0c392726f3db9c4fb43165f2be89e8 333 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 153 160 2.0E-8 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 VAPA_1c22580 7a0c392726f3db9c4fb43165f2be89e8 333 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 210 229 2.0E-8 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 VAPA_1c22580 7a0c392726f3db9c4fb43165f2be89e8 333 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 136 146 2.0E-8 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 VAPA_1c22580 7a0c392726f3db9c4fb43165f2be89e8 333 SUPERFAMILY SSF54292 5 96 1.97E-19 T 12-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 VAPA_1c22580 7a0c392726f3db9c4fb43165f2be89e8 333 SUPERFAMILY SSF52343 189 329 1.7E-30 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain VAPA_1c22580 7a0c392726f3db9c4fb43165f2be89e8 333 Gene3D G3DSA:3.40.50.80 199 332 2.0E-28 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain VAPA_1c22580 7a0c392726f3db9c4fb43165f2be89e8 333 Gene3D G3DSA:3.10.20.30 3 101 1.2E-19 T 12-10-2018 IPR012675 Beta-grasp domain superfamily VAPA_1c22580 7a0c392726f3db9c4fb43165f2be89e8 333 Pfam PF00175 Oxidoreductase NAD-binding domain 211 312 1.6E-17 T 12-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 VAPA_1c22580 7a0c392726f3db9c4fb43165f2be89e8 333 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 12 86 1.2E-9 T 12-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 VAPA_1c22580 7a0c392726f3db9c4fb43165f2be89e8 333 SUPERFAMILY SSF63380 78 204 4.44E-26 T 12-10-2018 IPR017938 Riboflavin synthase-like beta-barrel VAPA_1c22580 7a0c392726f3db9c4fb43165f2be89e8 333 Gene3D G3DSA:2.40.30.10 102 198 9.8E-26 T 12-10-2018 VAPA_1c22580 7a0c392726f3db9c4fb43165f2be89e8 333 PRINTS PR00410 Phenol hydroxylase reductase family signature 300 308 7.3E-22 T 12-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 VAPA_1c22580 7a0c392726f3db9c4fb43165f2be89e8 333 PRINTS PR00410 Phenol hydroxylase reductase family signature 210 229 7.3E-22 T 12-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 VAPA_1c22580 7a0c392726f3db9c4fb43165f2be89e8 333 PRINTS PR00410 Phenol hydroxylase reductase family signature 136 148 7.3E-22 T 12-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 VAPA_1c22580 7a0c392726f3db9c4fb43165f2be89e8 333 PRINTS PR00410 Phenol hydroxylase reductase family signature 153 160 7.3E-22 T 12-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 VAPA_1c22580 7a0c392726f3db9c4fb43165f2be89e8 333 PRINTS PR00410 Phenol hydroxylase reductase family signature 195 204 7.3E-22 T 12-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 VAPA_1c22580 7a0c392726f3db9c4fb43165f2be89e8 333 Pfam PF00970 Oxidoreductase FAD-binding domain 112 200 3.2E-14 T 12-10-2018 IPR008333 Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain Reactome: R-HSA-1237044 VAPA_1c22580 7a0c392726f3db9c4fb43165f2be89e8 333 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 42 50 - T 12-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 VAPA_1c24610 dd95611041b7e9a399bb3ae55eff8917 357 SUPERFAMILY SSF51735 2 197 8.31E-50 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c24610 dd95611041b7e9a399bb3ae55eff8917 357 Gene3D G3DSA:3.30.360.10 128 336 1.8E-128 T 12-10-2018 VAPA_1c24610 dd95611041b7e9a399bb3ae55eff8917 357 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 135 235 5.9E-12 T 12-10-2018 IPR004104 Oxidoreductase, C-terminal GO:0016491|GO:0055114 VAPA_1c24610 dd95611041b7e9a399bb3ae55eff8917 357 Gene3D G3DSA:3.40.50.720 7 324 1.8E-128 T 12-10-2018 VAPA_1c24610 dd95611041b7e9a399bb3ae55eff8917 357 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 6 121 1.5E-24 T 12-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 VAPA_1c03240 8baf8aea0ed8c8b75e184ffeb02ab0b0 571 TIGRFAM TIGR02713 allophanate_hyd: allophanate hydrolase 29 557 4.4E-218 T 12-10-2018 IPR014085 Allophanate hydrolase KEGG: 00220+3.5.1.54|KEGG: 00791+3.5.1.54|MetaCyc: PWY-5169|MetaCyc: PWY-5703 VAPA_1c03240 8baf8aea0ed8c8b75e184ffeb02ab0b0 571 Gene3D G3DSA:1.20.58.1700 252 325 1.3E-136 T 12-10-2018 VAPA_1c03240 8baf8aea0ed8c8b75e184ffeb02ab0b0 571 Gene3D G3DSA:3.10.490.10 429 566 4.2E-53 T 12-10-2018 VAPA_1c03240 8baf8aea0ed8c8b75e184ffeb02ab0b0 571 SUPERFAMILY SSF75304 12 407 1.7E-102 T 12-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 VAPA_1c03240 8baf8aea0ed8c8b75e184ffeb02ab0b0 571 Pfam PF01425 Amidase 12 393 5.5E-84 T 12-10-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 VAPA_1c03240 8baf8aea0ed8c8b75e184ffeb02ab0b0 571 Gene3D G3DSA:3.90.1300.10 24 399 1.3E-136 T 12-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 VAPA_1c26650 f4d86e38b2f50ccf71ee496ac53c0142 688 SUPERFAMILY SSF53474 414 670 7.4E-62 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c26650 f4d86e38b2f50ccf71ee496ac53c0142 688 Gene3D G3DSA:3.40.50.1820 355 679 4.7E-69 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c26650 f4d86e38b2f50ccf71ee496ac53c0142 688 SUPERFAMILY SSF82171 58 296 5.69E-8 T 12-10-2018 VAPA_1c26650 f4d86e38b2f50ccf71ee496ac53c0142 688 Pfam PF00326 Prolyl oligopeptidase family 466 665 4.8E-41 T 12-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 VAPA_1c26650 f4d86e38b2f50ccf71ee496ac53c0142 688 Gene3D G3DSA:2.120.10.30 35 238 8.5E-6 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like VAPA_1c25470 7c31e7c268123d635b4270f6ee1b8523 317 Gene3D G3DSA:3.40.50.620 23 226 8.8E-51 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold VAPA_1c25470 7c31e7c268123d635b4270f6ee1b8523 317 SUPERFAMILY SSF52402 21 224 1.3E-57 T 12-10-2018 VAPA_1c25470 7c31e7c268123d635b4270f6ee1b8523 317 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 46 269 3.7E-40 T 12-10-2018 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824 Reactome: R-HSA-196843 VAPA_1c25470 7c31e7c268123d635b4270f6ee1b8523 317 PIRSF PIRSF002936 16 317 1.0E-125 T 12-10-2018 IPR011784 Sulphate adenylyltransferase, small subunit GO:0004781|GO:0019419 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 VAPA_1c06260 1802464818afc8358b16f110820622e2 172 TIGRFAM TIGR03358 VI_chp_5: type VI secretion protein, VC_A0107 family 6 162 1.9E-56 T 12-10-2018 IPR008312 Type VI secretion system, VipA, VC_A0107 or Hcp2 VAPA_1c06260 1802464818afc8358b16f110820622e2 172 PIRSF PIRSF028301 1 171 1.4E-60 T 12-10-2018 IPR008312 Type VI secretion system, VipA, VC_A0107 or Hcp2 VAPA_1c06260 1802464818afc8358b16f110820622e2 172 Pfam PF05591 Type VI secretion system, VipA, VC_A0107 or Hcp2 10 160 8.1E-58 T 12-10-2018 IPR008312 Type VI secretion system, VipA, VC_A0107 or Hcp2 VAPA_1c34260 48763b20c13d86bdb7793d5e97f61f17 403 Gene3D G3DSA:1.10.275.10 1 102 1.6E-27 T 12-10-2018 IPR024083 Fumarase/histidase, N-terminal VAPA_1c34260 48763b20c13d86bdb7793d5e97f61f17 403 ProSitePatterns PS00163 Fumarate lyases signature. 273 282 - T 12-10-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 VAPA_1c34260 48763b20c13d86bdb7793d5e97f61f17 403 PRINTS PR00149 Fumarate lyase superfamily signature 273 289 6.1E-17 T 12-10-2018 IPR000362 Fumarate lyase family VAPA_1c34260 48763b20c13d86bdb7793d5e97f61f17 403 PRINTS PR00149 Fumarate lyase superfamily signature 143 161 6.1E-17 T 12-10-2018 IPR000362 Fumarate lyase family VAPA_1c34260 48763b20c13d86bdb7793d5e97f61f17 403 PRINTS PR00149 Fumarate lyase superfamily signature 98 116 6.1E-17 T 12-10-2018 IPR000362 Fumarate lyase family VAPA_1c34260 48763b20c13d86bdb7793d5e97f61f17 403 PRINTS PR00149 Fumarate lyase superfamily signature 228 255 6.1E-17 T 12-10-2018 IPR000362 Fumarate lyase family VAPA_1c34260 48763b20c13d86bdb7793d5e97f61f17 403 SUPERFAMILY SSF48557 6 375 2.83E-87 T 12-10-2018 IPR008948 L-Aspartase-like GO:0003824 VAPA_1c34260 48763b20c13d86bdb7793d5e97f61f17 403 Gene3D G3DSA:1.20.200.10 103 358 9.6E-86 T 12-10-2018 VAPA_1c34260 48763b20c13d86bdb7793d5e97f61f17 403 TIGRFAM TIGR02426 protocat_pcaB: 3-carboxy-cis,cis-muconate cycloisomerase 4 342 3.3E-111 T 12-10-2018 IPR012789 3-carboxy-cis,cis-muconate cycloisomerase GO:0019619|GO:0047472 KEGG: 00362+5.5.1.2 VAPA_1c34260 48763b20c13d86bdb7793d5e97f61f17 403 Pfam PF00206 Lyase 11 293 6.1E-40 T 12-10-2018 IPR022761 Fumarate lyase, N-terminal VAPA_1c34560 0a0437abafd58a6ae605bb68f06999ed 253 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 19 249 1.1E-57 T 12-10-2018 VAPA_1c34560 0a0437abafd58a6ae605bb68f06999ed 253 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 147 175 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 VAPA_1c34560 0a0437abafd58a6ae605bb68f06999ed 253 SUPERFAMILY SSF51735 9 250 8.95E-75 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c34560 0a0437abafd58a6ae605bb68f06999ed 253 Gene3D G3DSA:3.40.50.720 3 252 1.1E-76 T 12-10-2018 VAPA_1c34560 0a0437abafd58a6ae605bb68f06999ed 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 181 198 4.7E-40 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c34560 0a0437abafd58a6ae605bb68f06999ed 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 86 97 4.7E-40 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c34560 0a0437abafd58a6ae605bb68f06999ed 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 160 179 4.7E-40 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c34560 0a0437abafd58a6ae605bb68f06999ed 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 134 150 4.7E-40 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c34560 0a0437abafd58a6ae605bb68f06999ed 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 214 234 4.7E-40 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c34560 0a0437abafd58a6ae605bb68f06999ed 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 14 31 4.7E-40 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c34560 0a0437abafd58a6ae605bb68f06999ed 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 160 179 1.4E-13 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c34560 0a0437abafd58a6ae605bb68f06999ed 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 140 148 1.4E-13 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c34560 0a0437abafd58a6ae605bb68f06999ed 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 86 97 1.4E-13 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c54060 bf98b87748bb6e9dc9a239c404f4bbb5 481 Pfam PF00512 His Kinase A (phospho-acceptor) domain 245 309 6.8E-14 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 VAPA_1c54060 bf98b87748bb6e9dc9a239c404f4bbb5 481 SMART SM00388 244 310 2.9E-15 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 VAPA_1c54060 bf98b87748bb6e9dc9a239c404f4bbb5 481 SUPERFAMILY SSF55874 299 474 1.44E-31 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_1c54060 bf98b87748bb6e9dc9a239c404f4bbb5 481 PRINTS PR00344 Bacterial sensor protein C-terminal signature 402 416 1.1E-9 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c54060 bf98b87748bb6e9dc9a239c404f4bbb5 481 PRINTS PR00344 Bacterial sensor protein C-terminal signature 434 452 1.1E-9 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c54060 bf98b87748bb6e9dc9a239c404f4bbb5 481 PRINTS PR00344 Bacterial sensor protein C-terminal signature 420 430 1.1E-9 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c54060 bf98b87748bb6e9dc9a239c404f4bbb5 481 SUPERFAMILY SSF47384 227 309 8.63E-16 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 VAPA_1c54060 bf98b87748bb6e9dc9a239c404f4bbb5 481 Gene3D G3DSA:3.30.565.10 315 478 3.7E-29 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_1c54060 bf98b87748bb6e9dc9a239c404f4bbb5 481 SMART SM00387 359 478 3.2E-29 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase VAPA_1c54060 bf98b87748bb6e9dc9a239c404f4bbb5 481 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 360 474 6.0E-17 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase VAPA_1c54060 bf98b87748bb6e9dc9a239c404f4bbb5 481 Gene3D G3DSA:1.10.287.130 195 311 7.3E-20 T 12-10-2018 VAPA_1c54060 bf98b87748bb6e9dc9a239c404f4bbb5 481 Pfam PF08521 Two-component sensor kinase N-terminal 23 167 5.7E-39 T 12-10-2018 IPR013727 Two-component sensor kinase, N-terminal VAPA_1c33140 209b508c35ec14d976eb29efeb07e792 483 SUPERFAMILY SSF51905 39 438 2.24E-24 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c33140 209b508c35ec14d976eb29efeb07e792 483 PRINTS PR00419 Adrenodoxin reductase family signature 45 67 3.2E-5 T 12-10-2018 VAPA_1c33140 209b508c35ec14d976eb29efeb07e792 483 PRINTS PR00419 Adrenodoxin reductase family signature 68 81 3.2E-5 T 12-10-2018 VAPA_1c33140 209b508c35ec14d976eb29efeb07e792 483 Gene3D G3DSA:3.50.50.60 42 269 6.9E-16 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c33140 209b508c35ec14d976eb29efeb07e792 483 Pfam PF12831 FAD dependent oxidoreductase 46 458 3.6E-66 T 12-10-2018 IPR039649 Digeranylgeranylglycerophospholipid reductase, N-terminal VAPA_1c29180 1a83529b70bc8efe7f26cdce766042a6 335 SUPERFAMILY SSF51735 102 297 5.86E-50 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c29180 1a83529b70bc8efe7f26cdce766042a6 335 SUPERFAMILY SSF52283 1 136 1.28E-20 T 12-10-2018 VAPA_1c29180 1a83529b70bc8efe7f26cdce766042a6 335 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 111 296 9.7E-51 T 12-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 VAPA_1c29180 1a83529b70bc8efe7f26cdce766042a6 335 Gene3D G3DSA:3.40.50.720 104 312 1.5E-117 T 12-10-2018 VAPA_1c29180 1a83529b70bc8efe7f26cdce766042a6 335 Gene3D G3DSA:3.40.50.720 3 320 1.5E-117 T 12-10-2018 VAPA_1c29180 1a83529b70bc8efe7f26cdce766042a6 335 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 39 327 2.3E-17 T 12-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 VAPA_1c12070 62aa83eed65fa3fdc90bbf5dcbe963a9 420 Pfam PF07690 Major Facilitator Superfamily 20 376 1.9E-18 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 VAPA_1c12070 62aa83eed65fa3fdc90bbf5dcbe963a9 420 SUPERFAMILY SSF103473 10 412 3.01E-34 T 12-10-2018 IPR036259 MFS transporter superfamily VAPA_1c12070 62aa83eed65fa3fdc90bbf5dcbe963a9 420 Gene3D G3DSA:1.20.1250.20 7 410 8.5E-28 T 12-10-2018 VAPA_1c16130 36896b764db9ef84835a793e45c638ca 194 Gene3D G3DSA:1.20.120.1220 19 131 1.3E-7 T 12-10-2018 VAPA_1c16130 36896b764db9ef84835a793e45c638ca 194 Pfam PF01478 Type IV leader peptidase family 23 125 4.8E-16 T 12-10-2018 IPR000045 Prepilin type IV endopeptidase, peptidase domain GO:0004190|GO:0016020 VAPA_1c50000 8de2c5c5813ca2c928f52f9b62d231e2 223 ProSitePatterns PS01081 TetR-type HTH domain signature. 28 58 - T 12-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site VAPA_1c50000 8de2c5c5813ca2c928f52f9b62d231e2 223 SUPERFAMILY SSF46689 3 70 2.44E-18 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 VAPA_1c50000 8de2c5c5813ca2c928f52f9b62d231e2 223 Pfam PF08361 MAATS-type transcriptional repressor, C-terminal region 86 194 1.8E-17 T 12-10-2018 IPR013572 Transcription regulator MAATS, C-terminal GO:0003677 VAPA_1c50000 8de2c5c5813ca2c928f52f9b62d231e2 223 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 37 60 2.3E-10 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 VAPA_1c50000 8de2c5c5813ca2c928f52f9b62d231e2 223 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 16 29 2.3E-10 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 VAPA_1c50000 8de2c5c5813ca2c928f52f9b62d231e2 223 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 62 7.6E-17 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 VAPA_1c50000 8de2c5c5813ca2c928f52f9b62d231e2 223 SUPERFAMILY SSF48498 85 204 1.66E-12 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily VAPA_1c50000 8de2c5c5813ca2c928f52f9b62d231e2 223 Gene3D G3DSA:1.10.357.10 1 210 4.9E-54 T 12-10-2018 VAPA_1c22520 c629b31c094e908ab5afc98232ea69f7 485 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 255 262 - T 12-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 VAPA_1c22520 c629b31c094e908ab5afc98232ea69f7 485 Gene3D G3DSA:3.40.605.10 20 474 6.2E-189 T 12-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 VAPA_1c22520 c629b31c094e908ab5afc98232ea69f7 485 Pfam PF00171 Aldehyde dehydrogenase family 20 478 1.4E-176 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 VAPA_1c22520 c629b31c094e908ab5afc98232ea69f7 485 SUPERFAMILY SSF53720 9 482 6.54E-178 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 VAPA_1c22520 c629b31c094e908ab5afc98232ea69f7 485 TIGRFAM TIGR01780 SSADH: succinate-semialdehyde dehydrogenase 31 477 9.0E-217 T 12-10-2018 IPR010102 Succinate semialdehyde dehydrogenase GO:0009013|GO:0009450|GO:0055114 Reactome: R-HSA-916853 VAPA_1c22520 c629b31c094e908ab5afc98232ea69f7 485 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 283 294 - T 12-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 VAPA_1c22520 c629b31c094e908ab5afc98232ea69f7 485 Gene3D G3DSA:3.40.309.10 262 451 6.2E-189 T 12-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 VAPA_1c07480 4602efe8f1c0ac76e408a07415ea0231 233 Gene3D G3DSA:1.10.10.60 169 225 8.0E-13 T 12-10-2018 VAPA_1c07480 4602efe8f1c0ac76e408a07415ea0231 233 Gene3D G3DSA:3.40.50.2300 1 130 6.5E-36 T 12-10-2018 VAPA_1c07480 4602efe8f1c0ac76e408a07415ea0231 233 SUPERFAMILY SSF46689 145 223 1.57E-13 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 VAPA_1c07480 4602efe8f1c0ac76e408a07415ea0231 233 SUPERFAMILY SSF52172 1 125 1.71E-37 T 12-10-2018 IPR011006 CheY-like superfamily VAPA_1c07480 4602efe8f1c0ac76e408a07415ea0231 233 Pfam PF00072 Response regulator receiver domain 4 115 7.9E-27 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_1c07480 4602efe8f1c0ac76e408a07415ea0231 233 SMART SM00448 2 114 2.0E-32 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_1c03910 1bfbbeec00594c6556402386b355a94a 304 SUPERFAMILY SSF51735 18 257 1.63E-67 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c03910 1bfbbeec00594c6556402386b355a94a 304 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 94 105 3.0E-6 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c03910 1bfbbeec00594c6556402386b355a94a 304 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 147 155 3.0E-6 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c03910 1bfbbeec00594c6556402386b355a94a 304 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 166 185 3.0E-6 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c03910 1bfbbeec00594c6556402386b355a94a 304 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 166 185 1.9E-30 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c03910 1bfbbeec00594c6556402386b355a94a 304 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 20 37 1.9E-30 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c03910 1bfbbeec00594c6556402386b355a94a 304 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 223 243 1.9E-30 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c03910 1bfbbeec00594c6556402386b355a94a 304 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 187 204 1.9E-30 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c03910 1bfbbeec00594c6556402386b355a94a 304 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 94 105 1.9E-30 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c03910 1bfbbeec00594c6556402386b355a94a 304 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 141 157 1.9E-30 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c03910 1bfbbeec00594c6556402386b355a94a 304 Gene3D G3DSA:3.40.50.720 3 278 3.6E-74 T 12-10-2018 VAPA_1c03910 1bfbbeec00594c6556402386b355a94a 304 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 28 257 5.8E-50 T 12-10-2018 VAPA_1c47980 adc75ba360e23e0745571ec31a86d489 429 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 325 410 7.8E-13 T 12-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 VAPA_1c47980 adc75ba360e23e0745571ec31a86d489 429 Gene3D G3DSA:1.10.760.10 306 429 1.8E-29 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 VAPA_1c47980 adc75ba360e23e0745571ec31a86d489 429 SUPERFAMILY SSF46626 327 423 1.25E-24 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 VAPA_1c47980 adc75ba360e23e0745571ec31a86d489 429 SUPERFAMILY SSF46626 40 170 1.13E-25 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 VAPA_1c47980 adc75ba360e23e0745571ec31a86d489 429 PIRSF PIRSF000018 21 429 6.6E-131 T 12-10-2018 IPR014353 Membrane-bound alcohol dehydrogenase, cytochrome c subunit GO:0005506|GO:0016020|GO:0016614|GO:0020037 VAPA_1c47980 adc75ba360e23e0745571ec31a86d489 429 Gene3D G3DSA:1.10.760.10 2 155 1.2E-13 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 VAPA_1c47980 adc75ba360e23e0745571ec31a86d489 429 SUPERFAMILY SSF46626 195 312 2.58E-16 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 VAPA_1c47980 adc75ba360e23e0745571ec31a86d489 429 Gene3D G3DSA:1.10.760.10 172 305 1.2E-6 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 VAPA_1c47980 adc75ba360e23e0745571ec31a86d489 429 Pfam PF00034 Cytochrome c 205 301 3.6E-4 T 12-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 VAPA_1c47980 adc75ba360e23e0745571ec31a86d489 429 Pfam PF00034 Cytochrome c 50 149 7.0E-7 T 12-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 VAPA_2c09130 d938cb5b7388315e27b74d37b9483c0b 485 Gene3D G3DSA:2.40.180.10 10 485 5.6E-225 T 12-10-2018 IPR037060 Catalase core domain superfamily GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 VAPA_2c09130 d938cb5b7388315e27b74d37b9483c0b 485 ProSitePatterns PS00437 Catalase proximal heme-ligand signature. 340 348 - T 12-10-2018 IPR002226 Catalase haem-binding site GO:0020037 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 VAPA_2c09130 d938cb5b7388315e27b74d37b9483c0b 485 Pfam PF06628 Catalase-related immune-responsive 421 483 7.4E-22 T 12-10-2018 IPR010582 Catalase immune-responsive domain KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 VAPA_2c09130 d938cb5b7388315e27b74d37b9483c0b 485 PRINTS PR00067 Catalase signature 111 128 3.9E-71 T 12-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 VAPA_2c09130 d938cb5b7388315e27b74d37b9483c0b 485 PRINTS PR00067 Catalase signature 327 353 3.9E-71 T 12-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 VAPA_2c09130 d938cb5b7388315e27b74d37b9483c0b 485 PRINTS PR00067 Catalase signature 90 108 3.9E-71 T 12-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 VAPA_2c09130 d938cb5b7388315e27b74d37b9483c0b 485 PRINTS PR00067 Catalase signature 295 322 3.9E-71 T 12-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 VAPA_2c09130 d938cb5b7388315e27b74d37b9483c0b 485 PRINTS PR00067 Catalase signature 27 50 3.9E-71 T 12-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 VAPA_2c09130 d938cb5b7388315e27b74d37b9483c0b 485 PRINTS PR00067 Catalase signature 130 148 3.9E-71 T 12-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 VAPA_2c09130 d938cb5b7388315e27b74d37b9483c0b 485 SUPERFAMILY SSF56634 9 484 1.96E-210 T 12-10-2018 IPR020835 Catalase superfamily GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 VAPA_2c09130 d938cb5b7388315e27b74d37b9483c0b 485 PIRSF PIRSF038928 3 485 7.3E-222 T 12-10-2018 IPR024711 Catalase, mono-functional, haem-containing, clades 1 and 3 GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 VAPA_2c09130 d938cb5b7388315e27b74d37b9483c0b 485 Pfam PF00199 Catalase 14 395 4.1E-188 T 12-10-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 VAPA_2c09130 d938cb5b7388315e27b74d37b9483c0b 485 SMART SM01060 14 398 3.7E-284 T 12-10-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 VAPA_1c25630 71d4a7db1551b3ca24530be263da3fe2 297 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 10 67 5.2E-18 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c25630 71d4a7db1551b3ca24530be263da3fe2 297 SUPERFAMILY SSF46785 4 82 5.45E-21 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c25630 71d4a7db1551b3ca24530be263da3fe2 297 Gene3D G3DSA:3.40.190.10 164 264 2.3E-50 T 12-10-2018 VAPA_1c25630 71d4a7db1551b3ca24530be263da3fe2 297 Gene3D G3DSA:3.40.190.10 104 290 2.3E-50 T 12-10-2018 VAPA_1c25630 71d4a7db1551b3ca24530be263da3fe2 297 Gene3D G3DSA:1.10.10.10 7 92 4.1E-22 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c25630 71d4a7db1551b3ca24530be263da3fe2 297 SUPERFAMILY SSF53850 97 295 2.17E-34 T 12-10-2018 VAPA_1c25630 71d4a7db1551b3ca24530be263da3fe2 297 Pfam PF03466 LysR substrate binding domain 97 292 9.4E-33 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_1c25630 71d4a7db1551b3ca24530be263da3fe2 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 23 34 3.2E-9 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c25630 71d4a7db1551b3ca24530be263da3fe2 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 44 3.2E-9 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c25630 71d4a7db1551b3ca24530be263da3fe2 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 44 55 3.2E-9 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c41820 1cd57867e897cb3efcfb737b90d4a7ce 155 Gene3D G3DSA:3.30.1370.110 20 155 4.0E-42 T 12-10-2018 VAPA_1c41820 1cd57867e897cb3efcfb737b90d4a7ce 155 SMART SM00463 67 151 1.6E-11 T 12-10-2018 IPR002625 Smr domain VAPA_1c41820 1cd57867e897cb3efcfb737b90d4a7ce 155 SUPERFAMILY SSF160443 68 150 1.7E-18 T 12-10-2018 IPR036063 Smr domain superfamily VAPA_1c41820 1cd57867e897cb3efcfb737b90d4a7ce 155 Pfam PF01713 Smr domain 70 150 2.7E-24 T 12-10-2018 IPR002625 Smr domain VAPA_1c40030 f06e105e8685da166279c2e804ea5e69 842 Gene3D G3DSA:2.30.120.10 334 411 2.6E-222 T 12-10-2018 VAPA_1c40030 f06e105e8685da166279c2e804ea5e69 842 Pfam PF01804 Penicillin amidase 55 830 5.9E-117 T 12-10-2018 IPR002692 Penicillin/GL-7-ACA/AHL/aculeacin-A acylase GO:0016787|GO:0017000 VAPA_1c40030 f06e105e8685da166279c2e804ea5e69 842 Gene3D G3DSA:1.10.1400.10 558 767 2.6E-222 T 12-10-2018 VAPA_1c40030 f06e105e8685da166279c2e804ea5e69 842 Gene3D G3DSA:1.10.439.10 46 222 5.5E-71 T 12-10-2018 IPR023343 Penicillin amidase type, domain 1 GO:0016811 VAPA_1c40030 f06e105e8685da166279c2e804ea5e69 842 SUPERFAMILY SSF56235 50 837 1.83E-140 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal VAPA_1c40030 f06e105e8685da166279c2e804ea5e69 842 Gene3D G3DSA:3.60.20.10 259 829 2.6E-222 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal VAPA_1c29520 4434cd5a64152b733783f11b18589123 307 ProSitePatterns PS01127 Elongation factor Ts signature 2. 75 85 - T 12-10-2018 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 VAPA_1c29520 4434cd5a64152b733783f11b18589123 307 Gene3D G3DSA:3.30.479.20 157 282 9.1E-32 T 12-10-2018 IPR036402 Elongation factor Ts, dimerisation domain superfamily Reactome: R-HSA-5389840 VAPA_1c29520 4434cd5a64152b733783f11b18589123 307 TIGRFAM TIGR00116 tsf: translation elongation factor Ts 1 300 1.1E-82 T 12-10-2018 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 VAPA_1c29520 4434cd5a64152b733783f11b18589123 307 Gene3D G3DSA:1.10.286.20 192 248 9.1E-32 T 12-10-2018 VAPA_1c29520 4434cd5a64152b733783f11b18589123 307 SUPERFAMILY SSF54713 56 148 4.84E-21 T 12-10-2018 IPR036402 Elongation factor Ts, dimerisation domain superfamily Reactome: R-HSA-5389840 VAPA_1c29520 4434cd5a64152b733783f11b18589123 307 SUPERFAMILY SSF46934 3 56 2.55E-13 T 12-10-2018 IPR009060 UBA-like superfamily GO:0005515 VAPA_1c29520 4434cd5a64152b733783f11b18589123 307 Pfam PF00889 Elongation factor TS 73 283 1.6E-61 T 12-10-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0006414 Reactome: R-HSA-5389840 VAPA_1c29520 4434cd5a64152b733783f11b18589123 307 Gene3D G3DSA:3.30.479.20 57 151 1.3E-22 T 12-10-2018 IPR036402 Elongation factor Ts, dimerisation domain superfamily Reactome: R-HSA-5389840 VAPA_1c29520 4434cd5a64152b733783f11b18589123 307 Gene3D G3DSA:1.10.8.10 1 56 5.1E-20 T 12-10-2018 VAPA_1c29520 4434cd5a64152b733783f11b18589123 307 Hamap MF_00050 Elongation factor Ts [tsf]. 1 300 74.13 T 12-10-2018 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 VAPA_1c29520 4434cd5a64152b733783f11b18589123 307 SUPERFAMILY SSF54713 153 300 6.62E-43 T 12-10-2018 IPR036402 Elongation factor Ts, dimerisation domain superfamily Reactome: R-HSA-5389840 VAPA_2c00240 ea9d2b486839182850e083a3af3aa948 199 Pfam PF03861 ANTAR domain 137 189 5.5E-12 T 12-10-2018 IPR005561 ANTAR domain GO:0003723 VAPA_2c00240 ea9d2b486839182850e083a3af3aa948 199 SUPERFAMILY SSF52172 3 189 2.86E-38 T 12-10-2018 IPR011006 CheY-like superfamily VAPA_2c00240 ea9d2b486839182850e083a3af3aa948 199 Gene3D G3DSA:3.40.50.2300 2 125 1.3E-36 T 12-10-2018 VAPA_2c00240 ea9d2b486839182850e083a3af3aa948 199 SMART SM01012 134 189 8.0E-14 T 12-10-2018 IPR005561 ANTAR domain GO:0003723 VAPA_2c00240 ea9d2b486839182850e083a3af3aa948 199 Gene3D G3DSA:1.10.10.10 136 194 1.4E-13 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_2c00240 ea9d2b486839182850e083a3af3aa948 199 PIRSF PIRSF036382 1 196 3.0E-45 T 12-10-2018 IPR008327 Signal transduction response regulator, antiterminator VAPA_1c20280 523edb0cd42db89fed38d25f57cac208 346 Pfam PF12833 Helix-turn-helix domain 255 330 1.4E-12 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 VAPA_1c20280 523edb0cd42db89fed38d25f57cac208 346 Pfam PF12625 Arabinose-binding domain of AraC transcription regulator, N-term 21 204 2.9E-47 T 12-10-2018 IPR032687 HTH-type transcriptional regulator AraC-type, N-terminal VAPA_1c20280 523edb0cd42db89fed38d25f57cac208 346 SMART SM00342 247 329 1.5E-14 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 VAPA_1c20280 523edb0cd42db89fed38d25f57cac208 346 Gene3D G3DSA:1.10.10.60 229 341 1.0E-17 T 12-10-2018 VAPA_1c20280 523edb0cd42db89fed38d25f57cac208 346 SUPERFAMILY SSF46689 282 331 7.17E-7 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 VAPA_1c25750 948389f467b00d222260fe403deac57e 319 SUPERFAMILY SSF53850 34 256 5.6E-43 T 12-10-2018 VAPA_1c25750 948389f467b00d222260fe403deac57e 319 Gene3D G3DSA:3.40.190.10 36 308 1.9E-102 T 12-10-2018 VAPA_1c25750 948389f467b00d222260fe403deac57e 319 Pfam PF09084 NMT1/THI5 like 62 206 1.6E-13 T 12-10-2018 IPR015168 SsuA/THI5-like VAPA_1c25750 948389f467b00d222260fe403deac57e 319 TIGRFAM TIGR01728 SsuA_fam: ABC transporter, substrate-binding protein, aliphatic sulfonates family 36 310 6.7E-62 T 12-10-2018 IPR010067 Aliphatic sulfonates-binding protein GO:0016020|GO:0042626 VAPA_1c25750 948389f467b00d222260fe403deac57e 319 Gene3D G3DSA:1.10.8.450 245 277 1.9E-102 T 12-10-2018 VAPA_1c25750 948389f467b00d222260fe403deac57e 319 Gene3D G3DSA:3.40.190.10 114 213 1.9E-102 T 12-10-2018 VAPA_1c25750 948389f467b00d222260fe403deac57e 319 SMART SM00062 35 257 8.4E-15 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF VAPA_2c03530 bb63571175fe971e81f2f4f9ff2ed4f9 542 TIGRFAM TIGR02348 GroEL: chaperonin GroL 3 524 1.1E-231 T 12-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 VAPA_2c03530 bb63571175fe971e81f2f4f9ff2ed4f9 542 SUPERFAMILY SSF48592 10 522 6.25E-68 T 12-10-2018 IPR027413 GroEL-like equatorial domain superfamily VAPA_2c03530 bb63571175fe971e81f2f4f9ff2ed4f9 542 Gene3D G3DSA:3.30.260.10 136 410 1.5E-222 T 12-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily VAPA_2c03530 bb63571175fe971e81f2f4f9ff2ed4f9 542 Hamap MF_00600 60 kDa chaperonin [groL]. 2 541 37.402 T 12-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 VAPA_2c03530 bb63571175fe971e81f2f4f9ff2ed4f9 542 PRINTS PR00298 60kDa chaperonin signature 398 419 2.3E-66 T 12-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 VAPA_2c03530 bb63571175fe971e81f2f4f9ff2ed4f9 542 PRINTS PR00298 60kDa chaperonin signature 83 110 2.3E-66 T 12-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 VAPA_2c03530 bb63571175fe971e81f2f4f9ff2ed4f9 542 PRINTS PR00298 60kDa chaperonin signature 350 375 2.3E-66 T 12-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 VAPA_2c03530 bb63571175fe971e81f2f4f9ff2ed4f9 542 PRINTS PR00298 60kDa chaperonin signature 268 291 2.3E-66 T 12-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 VAPA_2c03530 bb63571175fe971e81f2f4f9ff2ed4f9 542 PRINTS PR00298 60kDa chaperonin signature 27 53 2.3E-66 T 12-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 VAPA_2c03530 bb63571175fe971e81f2f4f9ff2ed4f9 542 SUPERFAMILY SSF54849 137 203 1.97E-20 T 12-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily VAPA_2c03530 bb63571175fe971e81f2f4f9ff2ed4f9 542 Pfam PF00118 TCP-1/cpn60 chaperonin family 23 523 1.0E-89 T 12-10-2018 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 VAPA_2c03530 bb63571175fe971e81f2f4f9ff2ed4f9 542 SUPERFAMILY SSF52029 185 376 1.2E-72 T 12-10-2018 IPR027409 GroEL-like apical domain superfamily VAPA_2c03530 bb63571175fe971e81f2f4f9ff2ed4f9 542 Gene3D G3DSA:3.50.7.10 192 372 1.5E-222 T 12-10-2018 IPR027409 GroEL-like apical domain superfamily VAPA_2c03530 bb63571175fe971e81f2f4f9ff2ed4f9 542 Gene3D G3DSA:1.10.560.10 8 522 1.5E-222 T 12-10-2018 IPR027413 GroEL-like equatorial domain superfamily VAPA_2c03530 bb63571175fe971e81f2f4f9ff2ed4f9 542 ProSitePatterns PS00296 Chaperonins cpn60 signature. 405 416 - T 12-10-2018 IPR018370 Chaperonin Cpn60, conserved site GO:0005524|GO:0005737|GO:0006457 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 VAPA_1c03030 8bda37aba0fb4726b0accff0d568b234 527 Gene3D G3DSA:1.25.40.10 198 397 5.1E-6 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 VAPA_1c12850 75da55c30057ae6477f3d3828c78b7e9 207 Gene3D G3DSA:2.30.110.10 2 195 7.2E-49 T 12-10-2018 IPR012349 FMN-binding split barrel GO:0048037 VAPA_1c12850 75da55c30057ae6477f3d3828c78b7e9 207 Pfam PF01613 Flavin reductase like domain 21 163 4.5E-19 T 12-10-2018 IPR002563 Flavin reductase like domain GO:0010181 VAPA_1c12850 75da55c30057ae6477f3d3828c78b7e9 207 SUPERFAMILY SSF50475 7 193 3.02E-43 T 12-10-2018 VAPA_1c12850 75da55c30057ae6477f3d3828c78b7e9 207 SMART SM00903 16 168 6.3E-29 T 12-10-2018 IPR002563 Flavin reductase like domain GO:0010181 VAPA_1c29400 93062d68724313f293b64e022ace217a 382 Hamap MF_00392 Lipid-A-disaccharide synthase [lpxB]. 6 381 35.185 T 12-10-2018 IPR003835 Glycosyl transferase, family 19 GO:0008915|GO:0009245 KEGG: 00540+2.4.1.182 VAPA_1c29400 93062d68724313f293b64e022ace217a 382 SUPERFAMILY SSF53756 8 379 3.27E-26 T 12-10-2018 VAPA_1c29400 93062d68724313f293b64e022ace217a 382 TIGRFAM TIGR00215 lpxB: lipid-A-disaccharide synthase 9 381 3.3E-96 T 12-10-2018 IPR003835 Glycosyl transferase, family 19 GO:0008915|GO:0009245 KEGG: 00540+2.4.1.182 VAPA_1c29400 93062d68724313f293b64e022ace217a 382 Pfam PF02684 Lipid-A-disaccharide synthetase 10 370 2.1E-94 T 12-10-2018 IPR003835 Glycosyl transferase, family 19 GO:0008915|GO:0009245 KEGG: 00540+2.4.1.182 VAPA_1c16970 80782f9347e2175b25cd65620e62b216 163 PIRSF PIRSF019239 1 163 3.1E-33 T 12-10-2018 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 VAPA_1c16970 80782f9347e2175b25cd65620e62b216 163 Pfam PF01899 Na+/H+ ion antiporter subunit 12 160 1.8E-34 T 12-10-2018 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 VAPA_1c34850 4fa642f6404767596df4b74b58b1abf0 349 Gene3D G3DSA:3.40.50.360 33 183 5.2E-16 T 12-10-2018 IPR029039 Flavoprotein-like superfamily VAPA_1c34850 4fa642f6404767596df4b74b58b1abf0 349 SUPERFAMILY SSF52218 37 186 6.9E-9 T 12-10-2018 IPR029039 Flavoprotein-like superfamily VAPA_1c19190 c456f8aabd963382bd8bbdfda60b8acc 421 Gene3D G3DSA:2.40.340.10 346 411 2.2E-123 T 12-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 VAPA_1c19190 c456f8aabd963382bd8bbdfda60b8acc 421 SUPERFAMILY SSF63867 346 417 6.15E-15 T 12-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 VAPA_1c19190 c456f8aabd963382bd8bbdfda60b8acc 421 Pfam PF00994 Probable molybdopterin binding domain 188 334 3.3E-28 T 12-10-2018 IPR001453 MoaB/Mog domain VAPA_1c19190 c456f8aabd963382bd8bbdfda60b8acc 421 Gene3D G3DSA:3.90.105.10 29 181 2.2E-123 T 12-10-2018 VAPA_1c19190 c456f8aabd963382bd8bbdfda60b8acc 421 Pfam PF03453 MoeA N-terminal region (domain I and II) 11 174 1.7E-41 T 12-10-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 VAPA_1c19190 c456f8aabd963382bd8bbdfda60b8acc 421 SUPERFAMILY SSF63882 6 183 1.06E-48 T 12-10-2018 IPR036135 MoeA, N-terminal and linker domain superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 VAPA_1c19190 c456f8aabd963382bd8bbdfda60b8acc 421 SMART SM00852 187 336 2.7E-44 T 12-10-2018 IPR001453 MoaB/Mog domain VAPA_1c19190 c456f8aabd963382bd8bbdfda60b8acc 421 Gene3D G3DSA:2.170.190.11 52 148 2.2E-123 T 12-10-2018 VAPA_1c19190 c456f8aabd963382bd8bbdfda60b8acc 421 Gene3D G3DSA:3.40.980.10 182 345 2.2E-123 T 12-10-2018 IPR036425 MoaB/Mog-like domain superfamily VAPA_1c19190 c456f8aabd963382bd8bbdfda60b8acc 421 Pfam PF03454 MoeA C-terminal region (domain IV) 350 416 2.1E-9 T 12-10-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 VAPA_1c19190 c456f8aabd963382bd8bbdfda60b8acc 421 SUPERFAMILY SSF53218 184 340 4.58E-40 T 12-10-2018 IPR036425 MoaB/Mog-like domain superfamily VAPA_1c19190 c456f8aabd963382bd8bbdfda60b8acc 421 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 184 332 6.1E-28 T 12-10-2018 IPR001453 MoaB/Mog domain VAPA_1c20610 3e46afe09154dc8f8e6c25cbfbc73768 385 Pfam PF02563 Polysaccharide biosynthesis/export protein 86 178 1.4E-20 T 12-10-2018 IPR003715 Polysaccharide export protein GO:0015159|GO:0015774|GO:0016020 VAPA_1c20610 3e46afe09154dc8f8e6c25cbfbc73768 385 Pfam PF10531 SLBB domain 186 237 1.0E-7 T 12-10-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VAPA_1c20610 3e46afe09154dc8f8e6c25cbfbc73768 385 Gene3D G3DSA:3.30.1950.10 93 182 1.5E-90 T 12-10-2018 VAPA_1c20610 3e46afe09154dc8f8e6c25cbfbc73768 385 Gene3D G3DSA:3.10.560.10 71 267 1.5E-90 T 12-10-2018 VAPA_1c20610 3e46afe09154dc8f8e6c25cbfbc73768 385 Gene3D G3DSA:3.10.560.10 59 352 1.5E-90 T 12-10-2018 VAPA_2c09230 31a239c1f2b078d466589bf106e6e6af 322 Pfam PF03466 LysR substrate binding domain 103 308 3.9E-23 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_2c09230 31a239c1f2b078d466589bf106e6e6af 322 SUPERFAMILY SSF53850 103 312 4.03E-24 T 12-10-2018 VAPA_2c09230 31a239c1f2b078d466589bf106e6e6af 322 Gene3D G3DSA:1.10.10.10 14 102 1.4E-18 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_2c09230 31a239c1f2b078d466589bf106e6e6af 322 SUPERFAMILY SSF46785 14 87 1.11E-15 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_2c09230 31a239c1f2b078d466589bf106e6e6af 322 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 17 73 6.7E-17 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_2c09230 31a239c1f2b078d466589bf106e6e6af 322 Gene3D G3DSA:3.40.190.10 117 292 8.1E-27 T 12-10-2018 VAPA_2c09230 31a239c1f2b078d466589bf106e6e6af 322 Gene3D G3DSA:3.40.190.10 177 281 8.1E-27 T 12-10-2018 VAPA_2c09230 31a239c1f2b078d466589bf106e6e6af 322 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 52 63 2.5E-5 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_2c09230 31a239c1f2b078d466589bf106e6e6af 322 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 42 2.5E-5 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_2c09230 31a239c1f2b078d466589bf106e6e6af 322 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 52 2.5E-5 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c28330 26d567264b1fd08074eeb4fd09a404aa 313 SUPERFAMILY SSF46785 12 109 3.81E-12 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c28330 26d567264b1fd08074eeb4fd09a404aa 313 Pfam PF03466 LysR substrate binding domain 89 295 2.0E-44 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_1c28330 26d567264b1fd08074eeb4fd09a404aa 313 Gene3D G3DSA:3.40.190.10 91 303 1.2E-85 T 12-10-2018 VAPA_1c28330 26d567264b1fd08074eeb4fd09a404aa 313 Gene3D G3DSA:3.40.190.10 167 267 1.2E-85 T 12-10-2018 VAPA_1c28330 26d567264b1fd08074eeb4fd09a404aa 313 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 11 64 1.1E-14 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c28330 26d567264b1fd08074eeb4fd09a404aa 313 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 2.8E-9 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c28330 26d567264b1fd08074eeb4fd09a404aa 313 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 2.8E-9 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c28330 26d567264b1fd08074eeb4fd09a404aa 313 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 2.8E-9 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c28330 26d567264b1fd08074eeb4fd09a404aa 313 SUPERFAMILY SSF53850 91 298 2.96E-42 T 12-10-2018 VAPA_1c28330 26d567264b1fd08074eeb4fd09a404aa 313 Gene3D G3DSA:1.10.10.10 1 86 2.1E-17 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c33190 11f44224179c69852fc094407c331e9c 314 SUPERFAMILY SSF46785 4 112 9.02E-22 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c33190 11f44224179c69852fc094407c331e9c 314 Gene3D G3DSA:1.10.10.10 3 90 1.8E-26 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c33190 11f44224179c69852fc094407c331e9c 314 Gene3D G3DSA:3.40.190.290 92 292 2.0E-51 T 12-10-2018 VAPA_1c33190 11f44224179c69852fc094407c331e9c 314 SUPERFAMILY SSF53850 90 297 1.36E-39 T 12-10-2018 VAPA_1c33190 11f44224179c69852fc094407c331e9c 314 Pfam PF03466 LysR substrate binding domain 88 293 6.0E-40 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_1c33190 11f44224179c69852fc094407c331e9c 314 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 62 5.9E-20 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c45150 9af2fb7eff0957028688b92d512fe461 323 Gene3D G3DSA:3.40.50.2020 152 293 1.0E-132 T 12-10-2018 VAPA_1c45150 9af2fb7eff0957028688b92d512fe461 323 ProSitePatterns PS00114 Phosphoribosyl pyrophosphate synthase signature. 133 148 - T 12-10-2018 IPR000842 Phosphoribosyl pyrophosphate synthetase, conserved site GO:0000287|GO:0004749|GO:0009156|GO:0044249 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|Reactome: R-HSA-73843 VAPA_1c45150 9af2fb7eff0957028688b92d512fe461 323 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 9 317 5.0E-128 T 12-10-2018 IPR005946 Ribose-phosphate pyrophosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 VAPA_1c45150 9af2fb7eff0957028688b92d512fe461 323 SUPERFAMILY SSF53271 73 307 2.5E-68 T 12-10-2018 IPR029057 Phosphoribosyltransferase-like VAPA_1c45150 9af2fb7eff0957028688b92d512fe461 323 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 9 125 4.0E-48 T 12-10-2018 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 VAPA_1c45150 9af2fb7eff0957028688b92d512fe461 323 Hamap MF_00583_B Putative ribose-phosphate pyrophosphokinase [prs]. 8 317 49.738 T 12-10-2018 IPR037515 Ribose-phosphate pyrophosphokinase, bacterial-type GO:0004749 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|Reactome: R-HSA-73843 VAPA_1c45150 9af2fb7eff0957028688b92d512fe461 323 Pfam PF14572 Phosphoribosyl synthetase-associated domain 207 316 1.7E-31 T 12-10-2018 IPR005946 Ribose-phosphate pyrophosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 VAPA_1c45150 9af2fb7eff0957028688b92d512fe461 323 SMART SM01400 8 125 5.0E-75 T 12-10-2018 VAPA_1c45150 9af2fb7eff0957028688b92d512fe461 323 Gene3D G3DSA:3.40.50.2020 11 305 1.0E-132 T 12-10-2018 VAPA_1c01690 b6d8a4ce6358a7aa8d23fc3641d2e237 320 Pfam PF02653 Branched-chain amino acid transport system / permease component 34 299 1.0E-34 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 VAPA_2c09090 d89a4e73e61c2750653ca45198967f49 159 SUPERFAMILY SSF69118 5 144 9.3E-42 T 12-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 VAPA_2c09090 d89a4e73e61c2750653ca45198967f49 159 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 35 78 9.2E-13 T 12-10-2018 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 VAPA_2c09090 d89a4e73e61c2750653ca45198967f49 159 Pfam PF02627 Carboxymuconolactone decarboxylase family 12 93 6.1E-19 T 12-10-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 VAPA_2c09090 d89a4e73e61c2750653ca45198967f49 159 Gene3D G3DSA:1.20.1290.10 1 147 6.8E-46 T 12-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 VAPA_1c09000 83ddf1e2ff8642a754f1cc4d91d73131 402 Gene3D G3DSA:3.40.50.10540 9 396 1.4E-134 T 12-10-2018 IPR023606 CoA-transferase family III domain superfamily VAPA_1c09000 83ddf1e2ff8642a754f1cc4d91d73131 402 Pfam PF02515 CoA-transferase family III 10 377 6.2E-127 T 12-10-2018 IPR003673 CoA-transferase family III GO:0003824 VAPA_1c09000 83ddf1e2ff8642a754f1cc4d91d73131 402 Gene3D G3DSA:3.30.1540.10 237 329 1.4E-134 T 12-10-2018 VAPA_1c09000 83ddf1e2ff8642a754f1cc4d91d73131 402 SUPERFAMILY SSF89796 8 402 5.89E-135 T 12-10-2018 IPR023606 CoA-transferase family III domain superfamily VAPA_1c35030 95226db0afd17392ff59673138e082c7 334 Pfam PF01841 Transglutaminase-like superfamily 144 257 2.0E-19 T 12-10-2018 IPR002931 Transglutaminase-like VAPA_1c35030 95226db0afd17392ff59673138e082c7 334 SMART SM00460 177 259 3.4E-18 T 12-10-2018 IPR002931 Transglutaminase-like VAPA_1c35030 95226db0afd17392ff59673138e082c7 334 Pfam PF08379 Bacterial transglutaminase-like N-terminal region 3 82 2.7E-21 T 12-10-2018 IPR013589 Bacterial transglutaminase-like, N-terminal VAPA_1c35030 95226db0afd17392ff59673138e082c7 334 Gene3D G3DSA:3.10.620.30 101 295 4.6E-49 T 12-10-2018 VAPA_1c35030 95226db0afd17392ff59673138e082c7 334 SUPERFAMILY SSF54001 95 284 3.22E-44 T 12-10-2018 IPR038765 Papain-like cysteine peptidase superfamily VAPA_1c14010 a0701eb549bfa15df1d6911da10ac578 306 Gene3D G3DSA:1.10.10.10 1 90 1.6E-30 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c14010 a0701eb549bfa15df1d6911da10ac578 306 SUPERFAMILY SSF46785 1 85 3.11E-24 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c14010 a0701eb549bfa15df1d6911da10ac578 306 Pfam PF03466 LysR substrate binding domain 87 298 1.5E-34 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_1c14010 a0701eb549bfa15df1d6911da10ac578 306 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 1.6E-22 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c14010 a0701eb549bfa15df1d6911da10ac578 306 Gene3D G3DSA:3.40.190.10 91 292 3.4E-53 T 12-10-2018 VAPA_1c14010 a0701eb549bfa15df1d6911da10ac578 306 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.9E-9 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c14010 a0701eb549bfa15df1d6911da10ac578 306 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.9E-9 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c14010 a0701eb549bfa15df1d6911da10ac578 306 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.9E-9 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c14010 a0701eb549bfa15df1d6911da10ac578 306 Gene3D G3DSA:3.40.190.10 164 275 3.4E-53 T 12-10-2018 VAPA_1c14010 a0701eb549bfa15df1d6911da10ac578 306 SUPERFAMILY SSF53850 88 304 1.16E-31 T 12-10-2018 VAPA_1c22930 5d1010a2d4a7e19514721e3cc3532b11 261 SUPERFAMILY SSF46785 11 85 3.16E-14 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c22930 5d1010a2d4a7e19514721e3cc3532b11 261 SUPERFAMILY SSF55781 82 256 2.22E-37 T 12-10-2018 VAPA_1c22930 5d1010a2d4a7e19514721e3cc3532b11 261 Gene3D G3DSA:1.10.10.10 7 82 6.4E-19 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c22930 5d1010a2d4a7e19514721e3cc3532b11 261 Gene3D G3DSA:3.30.450.40 85 253 8.0E-34 T 12-10-2018 IPR029016 GAF-like domain superfamily VAPA_1c22930 5d1010a2d4a7e19514721e3cc3532b11 261 Pfam PF09339 IclR helix-turn-helix domain 13 63 3.0E-14 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 VAPA_1c22930 5d1010a2d4a7e19514721e3cc3532b11 261 Pfam PF01614 Bacterial transcriptional regulator 131 253 7.6E-9 T 12-10-2018 IPR014757 Transcription regulator IclR, C-terminal VAPA_1c22930 5d1010a2d4a7e19514721e3cc3532b11 261 SMART SM00346 11 101 4.3E-25 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 VAPA_1c15100 f934b2161ea17a98c980f77844d12223 270 SUPERFAMILY SSF55120 2 251 3.31E-81 T 12-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 VAPA_1c15100 f934b2161ea17a98c980f77844d12223 270 Pfam PF01416 tRNA pseudouridine synthase 8 101 8.0E-8 T 12-10-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 VAPA_1c15100 f934b2161ea17a98c980f77844d12223 270 Pfam PF01416 tRNA pseudouridine synthase 142 245 2.0E-26 T 12-10-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 VAPA_1c15100 f934b2161ea17a98c980f77844d12223 270 PIRSF PIRSF001430 1 259 6.7E-68 T 12-10-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 VAPA_1c15100 f934b2161ea17a98c980f77844d12223 270 TIGRFAM TIGR00071 hisT_truA: tRNA pseudouridine(38-40) synthase 3 241 1.1E-60 T 12-10-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 VAPA_1c15100 f934b2161ea17a98c980f77844d12223 270 Gene3D G3DSA:3.30.70.580 1 104 4.3E-37 T 12-10-2018 VAPA_1c15100 f934b2161ea17a98c980f77844d12223 270 Hamap MF_00171 tRNA pseudouridine synthase A [truA]. 1 247 31.456 T 12-10-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 VAPA_1c15100 f934b2161ea17a98c980f77844d12223 270 Gene3D G3DSA:3.30.70.660 105 244 1.3E-42 T 12-10-2018 IPR020095 Pseudouridine synthase I, TruA, C-terminal GO:0003723|GO:0009982 VAPA_1c04500 733d2e23d7641a1c498d87575245706f 503 SMART SM00382 280 482 5.0E-6 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c04500 733d2e23d7641a1c498d87575245706f 503 SMART SM00382 29 218 1.2E-8 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c04500 733d2e23d7641a1c498d87575245706f 503 SUPERFAMILY SSF52540 4 231 9.16E-57 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c04500 733d2e23d7641a1c498d87575245706f 503 SUPERFAMILY SSF52540 270 486 1.24E-44 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c04500 733d2e23d7641a1c498d87575245706f 503 Pfam PF00005 ABC transporter 272 426 6.0E-22 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c04500 733d2e23d7641a1c498d87575245706f 503 ProSitePatterns PS00211 ABC transporters family signature. 399 413 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_1c04500 733d2e23d7641a1c498d87575245706f 503 Gene3D G3DSA:3.40.50.300 1 244 1.2E-57 T 12-10-2018 VAPA_1c04500 733d2e23d7641a1c498d87575245706f 503 Gene3D G3DSA:3.40.50.300 249 494 4.9E-43 T 12-10-2018 VAPA_1c04500 733d2e23d7641a1c498d87575245706f 503 Pfam PF00005 ABC transporter 20 170 1.1E-28 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c34230 52cbd6470a65a189b251dfd4e9331d18 254 Pfam PF12146 Serine aminopeptidase, S33 15 227 2.9E-18 T 12-10-2018 IPR022742 Serine aminopeptidase, S33 VAPA_1c34230 52cbd6470a65a189b251dfd4e9331d18 254 SUPERFAMILY SSF53474 3 250 7.22E-60 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c34230 52cbd6470a65a189b251dfd4e9331d18 254 Gene3D G3DSA:3.40.50.1820 2 252 1.5E-63 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c34230 52cbd6470a65a189b251dfd4e9331d18 254 PRINTS PR00111 Alpha/beta hydrolase fold signature 38 53 8.3E-9 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 VAPA_1c34230 52cbd6470a65a189b251dfd4e9331d18 254 PRINTS PR00111 Alpha/beta hydrolase fold signature 97 110 8.3E-9 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 VAPA_1c34230 52cbd6470a65a189b251dfd4e9331d18 254 PRINTS PR00111 Alpha/beta hydrolase fold signature 198 212 8.3E-9 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 VAPA_1c34230 52cbd6470a65a189b251dfd4e9331d18 254 PRINTS PR00111 Alpha/beta hydrolase fold signature 83 96 8.3E-9 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 VAPA_1c15150 3fd16c63ffe1fb2b68d7bb3c29372d88 473 Pfam PF00330 Aconitase family (aconitate hydratase) 7 464 1.4E-157 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 VAPA_1c15150 3fd16c63ffe1fb2b68d7bb3c29372d88 473 ProSitePatterns PS01244 Aconitase family signature 2. 406 419 - T 12-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 VAPA_1c15150 3fd16c63ffe1fb2b68d7bb3c29372d88 473 TIGRFAM TIGR00170 leuC: 3-isopropylmalate dehydratase, large subunit 1 472 3.9E-235 T 12-10-2018 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 VAPA_1c15150 3fd16c63ffe1fb2b68d7bb3c29372d88 473 ProSitePatterns PS00450 Aconitase family signature 1. 343 359 - T 12-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 VAPA_1c15150 3fd16c63ffe1fb2b68d7bb3c29372d88 473 PRINTS PR00415 Aconitase family signature 290 304 6.3E-48 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 VAPA_1c15150 3fd16c63ffe1fb2b68d7bb3c29372d88 473 PRINTS PR00415 Aconitase family signature 347 358 6.3E-48 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 VAPA_1c15150 3fd16c63ffe1fb2b68d7bb3c29372d88 473 PRINTS PR00415 Aconitase family signature 199 212 6.3E-48 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 VAPA_1c15150 3fd16c63ffe1fb2b68d7bb3c29372d88 473 PRINTS PR00415 Aconitase family signature 123 136 6.3E-48 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 VAPA_1c15150 3fd16c63ffe1fb2b68d7bb3c29372d88 473 PRINTS PR00415 Aconitase family signature 137 152 6.3E-48 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 VAPA_1c15150 3fd16c63ffe1fb2b68d7bb3c29372d88 473 PRINTS PR00415 Aconitase family signature 406 419 6.3E-48 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 VAPA_1c15150 3fd16c63ffe1fb2b68d7bb3c29372d88 473 PRINTS PR00415 Aconitase family signature 85 98 6.3E-48 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 VAPA_1c15150 3fd16c63ffe1fb2b68d7bb3c29372d88 473 PRINTS PR00415 Aconitase family signature 112 120 6.3E-48 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 VAPA_1c15150 3fd16c63ffe1fb2b68d7bb3c29372d88 473 PRINTS PR00415 Aconitase family signature 213 226 6.3E-48 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 VAPA_1c15150 3fd16c63ffe1fb2b68d7bb3c29372d88 473 Hamap MF_01026 3-isopropylmalate dehydratase large subunit [leuC]. 1 473 60.261 T 12-10-2018 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 VAPA_1c15150 3fd16c63ffe1fb2b68d7bb3c29372d88 473 Gene3D G3DSA:3.30.499.10 331 473 2.4E-47 T 12-10-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 KEGG: 00290+4.2.1.33 VAPA_1c15150 3fd16c63ffe1fb2b68d7bb3c29372d88 473 SUPERFAMILY SSF53732 2 472 1.23E-162 T 12-10-2018 IPR036008 Aconitase, iron-sulfur domain KEGG: 00290+4.2.1.33 VAPA_1c15150 3fd16c63ffe1fb2b68d7bb3c29372d88 473 Gene3D G3DSA:3.30.499.20 4 290 2.7E-97 T 12-10-2018 VAPA_1c49400 d68af70133602fc0b3d08d01af3bfc1b 773 SUPERFAMILY SSF56935 54 772 4.48E-84 T 12-10-2018 VAPA_1c49400 d68af70133602fc0b3d08d01af3bfc1b 773 Pfam PF07715 TonB-dependent Receptor Plug Domain 56 168 7.0E-10 T 12-10-2018 IPR012910 TonB-dependent receptor, plug domain VAPA_1c49400 d68af70133602fc0b3d08d01af3bfc1b 773 Pfam PF00593 TonB dependent receptor 319 771 9.4E-46 T 12-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel VAPA_1c49400 d68af70133602fc0b3d08d01af3bfc1b 773 Gene3D G3DSA:2.170.130.10 33 179 1.1E-13 T 12-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily VAPA_1c35190 4c334da06b4b7e11bc6b348477fdaf1c 341 Gene3D G3DSA:1.10.260.40 1 64 2.7E-19 T 12-10-2018 VAPA_1c35190 4c334da06b4b7e11bc6b348477fdaf1c 341 SMART SM00354 6 77 1.9E-28 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 VAPA_1c35190 4c334da06b4b7e11bc6b348477fdaf1c 341 Pfam PF00356 Bacterial regulatory proteins, lacI family 8 54 2.9E-16 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 VAPA_1c35190 4c334da06b4b7e11bc6b348477fdaf1c 341 Gene3D G3DSA:3.40.50.2300 68 330 6.2E-62 T 12-10-2018 VAPA_1c35190 4c334da06b4b7e11bc6b348477fdaf1c 341 ProSitePatterns PS00356 LacI-type HTH domain signature. 9 27 - T 12-10-2018 VAPA_1c35190 4c334da06b4b7e11bc6b348477fdaf1c 341 SUPERFAMILY SSF47413 6 65 1.5E-13 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 VAPA_1c35190 4c334da06b4b7e11bc6b348477fdaf1c 341 Pfam PF13377 Periplasmic binding protein-like domain 175 338 7.0E-25 T 12-10-2018 VAPA_1c35190 4c334da06b4b7e11bc6b348477fdaf1c 341 Gene3D G3DSA:3.40.50.2300 166 335 6.2E-62 T 12-10-2018 VAPA_1c35190 4c334da06b4b7e11bc6b348477fdaf1c 341 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 18 28 1.6E-5 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 VAPA_1c35190 4c334da06b4b7e11bc6b348477fdaf1c 341 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 8 18 1.6E-5 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 VAPA_1c35190 4c334da06b4b7e11bc6b348477fdaf1c 341 SUPERFAMILY SSF53822 64 332 1.37E-54 T 12-10-2018 IPR028082 Periplasmic binding protein-like I VAPA_2c08500 68e1331d1ec6afaf6d9c20a8fb5c0c56 254 SUPERFAMILY SSF46785 8 77 8.85E-11 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_2c08500 68e1331d1ec6afaf6d9c20a8fb5c0c56 254 Gene3D G3DSA:3.30.450.40 80 247 7.0E-23 T 12-10-2018 IPR029016 GAF-like domain superfamily VAPA_2c08500 68e1331d1ec6afaf6d9c20a8fb5c0c56 254 SMART SM00346 6 96 2.2E-12 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 VAPA_2c08500 68e1331d1ec6afaf6d9c20a8fb5c0c56 254 Pfam PF09339 IclR helix-turn-helix domain 8 58 1.9E-14 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 VAPA_2c08500 68e1331d1ec6afaf6d9c20a8fb5c0c56 254 Gene3D G3DSA:1.10.10.10 2 73 5.2E-16 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_2c08500 68e1331d1ec6afaf6d9c20a8fb5c0c56 254 SUPERFAMILY SSF55781 81 244 1.5E-22 T 12-10-2018 VAPA_2c08500 68e1331d1ec6afaf6d9c20a8fb5c0c56 254 Pfam PF01614 Bacterial transcriptional regulator 130 228 1.9E-4 T 12-10-2018 IPR014757 Transcription regulator IclR, C-terminal VAPA_1c30950 f04b1bad290b72bd88fac2116a5aa9b1 267 Pfam PF13419 Haloacid dehalogenase-like hydrolase 6 197 8.4E-26 T 12-10-2018 VAPA_1c30950 f04b1bad290b72bd88fac2116a5aa9b1 267 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 162 182 3.3E-11 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 VAPA_1c30950 f04b1bad290b72bd88fac2116a5aa9b1 267 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 110 123 3.3E-11 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 VAPA_1c30950 f04b1bad290b72bd88fac2116a5aa9b1 267 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 144 160 3.3E-11 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 VAPA_1c30950 f04b1bad290b72bd88fac2116a5aa9b1 267 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 3 14 3.3E-11 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 VAPA_1c30950 f04b1bad290b72bd88fac2116a5aa9b1 267 Gene3D G3DSA:3.40.50.1000 5 217 6.7E-66 T 12-10-2018 IPR023214 HAD superfamily VAPA_1c30950 f04b1bad290b72bd88fac2116a5aa9b1 267 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 143 199 5.4E-12 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 VAPA_1c30950 f04b1bad290b72bd88fac2116a5aa9b1 267 SUPERFAMILY SSF56784 3 219 6.07E-42 T 12-10-2018 IPR036412 HAD-like superfamily VAPA_1c30950 f04b1bad290b72bd88fac2116a5aa9b1 267 Gene3D G3DSA:1.10.150.240 16 97 6.7E-66 T 12-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 VAPA_1c28440 b4b5e24381e2741ff4cb3362cf243b75 382 TIGRFAM TIGR01420 pilT_fam: twitching motility protein 4 343 7.8E-117 T 12-10-2018 IPR006321 Pilus retraction protein PilT GO:0005524 VAPA_1c28440 b4b5e24381e2741ff4cb3362cf243b75 382 Gene3D G3DSA:3.30.450.90 1 101 1.9E-22 T 12-10-2018 VAPA_1c28440 b4b5e24381e2741ff4cb3362cf243b75 382 Pfam PF00437 Type II/IV secretion system protein 9 260 2.0E-34 T 12-10-2018 IPR001482 Type II/IV secretion system protein VAPA_1c28440 b4b5e24381e2741ff4cb3362cf243b75 382 Gene3D G3DSA:3.40.50.300 102 357 2.4E-80 T 12-10-2018 VAPA_1c28440 b4b5e24381e2741ff4cb3362cf243b75 382 SUPERFAMILY SSF52540 3 335 1.16E-56 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c49170 9a4eb4bb3b57324872a72d3384d6daa7 457 SUPERFAMILY SSF56176 8 218 1.26E-35 T 12-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 VAPA_1c49170 9a4eb4bb3b57324872a72d3384d6daa7 457 SUPERFAMILY SSF55103 282 446 4.58E-6 T 12-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 VAPA_1c49170 9a4eb4bb3b57324872a72d3384d6daa7 457 Gene3D G3DSA:3.30.465.40 26 239 3.6E-34 T 12-10-2018 VAPA_1c49170 9a4eb4bb3b57324872a72d3384d6daa7 457 Pfam PF01565 FAD binding domain 51 180 9.1E-27 T 12-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 VAPA_2c06460 90c315f1783df06a6eaf00d6e30574d3 86 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 6 74 1.5E-17 T 12-10-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM VAPA_2c06460 90c315f1783df06a6eaf00d6e30574d3 86 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 10 60 2.0E-8 T 12-10-2018 VAPA_2c06460 90c315f1783df06a6eaf00d6e30574d3 86 SUPERFAMILY SSF143120 6 79 1.7E-16 T 12-10-2018 IPR036165 YefM-like superfamily VAPA_2c06460 90c315f1783df06a6eaf00d6e30574d3 86 Gene3D G3DSA:3.40.1620.40 9 64 1.7E-6 T 12-10-2018 VAPA_1c04060 cda83dbc48b1719179cd12d283c3fe25 508 PIRSF PIRSF000538 1 508 1.8E-152 T 12-10-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 VAPA_1c04060 cda83dbc48b1719179cd12d283c3fe25 508 SUPERFAMILY SSF53067 2 253 7.48E-64 T 12-10-2018 VAPA_1c04060 cda83dbc48b1719179cd12d283c3fe25 508 SUPERFAMILY SSF53067 252 503 1.3E-61 T 12-10-2018 VAPA_1c04060 cda83dbc48b1719179cd12d283c3fe25 508 Gene3D G3DSA:3.30.420.40 243 508 1.1E-71 T 12-10-2018 VAPA_1c04060 cda83dbc48b1719179cd12d283c3fe25 508 Gene3D G3DSA:3.30.420.40 1 241 1.0E-76 T 12-10-2018 VAPA_1c04060 cda83dbc48b1719179cd12d283c3fe25 508 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 368 388 - T 12-10-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 VAPA_1c04060 cda83dbc48b1719179cd12d283c3fe25 508 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 262 456 1.1E-40 T 12-10-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 VAPA_1c04060 cda83dbc48b1719179cd12d283c3fe25 508 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 3 250 9.6E-58 T 12-10-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 VAPA_1c12400 79cd71e71c4c43bd3d20a3835d07f027 152 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 21 40 4.9E-12 T 12-10-2018 VAPA_1c12400 79cd71e71c4c43bd3d20a3835d07f027 152 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 40 58 4.9E-12 T 12-10-2018 VAPA_1c12400 79cd71e71c4c43bd3d20a3835d07f027 152 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 1 21 4.9E-12 T 12-10-2018 VAPA_1c12400 79cd71e71c4c43bd3d20a3835d07f027 152 TIGRFAM TIGR01410 tatB: twin arginine-targeting protein translocase TatB 3 69 3.5E-17 T 12-10-2018 IPR018448 Twin-arginine translocation protein TatB GO:0016020|GO:0043953 VAPA_1c12400 79cd71e71c4c43bd3d20a3835d07f027 152 Pfam PF02416 mttA/Hcf106 family 4 47 2.5E-8 T 12-10-2018 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 VAPA_1c12400 79cd71e71c4c43bd3d20a3835d07f027 152 Hamap MF_00237 Sec-independent protein translocase protein TatB [tatB]. 1 115 14.888 T 12-10-2018 IPR018448 Twin-arginine translocation protein TatB GO:0016020|GO:0043953 VAPA_1c38720 cbb5a3221ff33795e7c377f880c9e7b1 330 Gene3D G3DSA:3.60.130.10 4 321 6.6E-98 T 12-10-2018 VAPA_1c38720 cbb5a3221ff33795e7c377f880c9e7b1 330 SUPERFAMILY SSF51197 6 320 9.62E-85 T 12-10-2018 VAPA_1c38720 cbb5a3221ff33795e7c377f880c9e7b1 330 Pfam PF02668 Taurine catabolism dioxygenase TauD, TfdA family 32 319 1.9E-47 T 12-10-2018 IPR003819 TauD/TfdA-like domain GO:0016491|GO:0055114 Reactome: R-HSA-71262 VAPA_2c02680 6163287b5343a7b468995c1cd739994c 127 Gene3D G3DSA:3.10.20.440 13 104 4.2E-8 T 12-10-2018 VAPA_2c02680 6163287b5343a7b468995c1cd739994c 127 SUPERFAMILY SSF54292 28 110 9.83E-19 T 12-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 VAPA_2c02680 6163287b5343a7b468995c1cd739994c 127 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 26 101 4.3E-22 T 12-10-2018 VAPA_1c26210 90d98e896a0292d908306e952a914323 547 Gene3D G3DSA:3.40.50.12780 2 440 9.8E-109 T 12-10-2018 VAPA_1c26210 90d98e896a0292d908306e952a914323 547 Pfam PF13193 AMP-binding enzyme C-terminal domain 454 529 8.8E-14 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain VAPA_1c26210 90d98e896a0292d908306e952a914323 547 Gene3D G3DSA:3.30.300.310 441 543 6.6E-30 T 12-10-2018 VAPA_1c26210 90d98e896a0292d908306e952a914323 547 ProSitePatterns PS00455 Putative AMP-binding domain signature. 183 194 - T 12-10-2018 IPR020845 AMP-binding, conserved site VAPA_1c26210 90d98e896a0292d908306e952a914323 547 SUPERFAMILY SSF56801 12 541 2.09E-123 T 12-10-2018 VAPA_1c26210 90d98e896a0292d908306e952a914323 547 Pfam PF00501 AMP-binding enzyme 30 445 2.3E-77 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 VAPA_2c05490 2f2f05ed29910b4af49d391a57bf7fbe 429 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 347 356 1.1E-18 T 12-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 VAPA_2c05490 2f2f05ed29910b4af49d391a57bf7fbe 429 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 132 151 1.1E-18 T 12-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 VAPA_2c05490 2f2f05ed29910b4af49d391a57bf7fbe 429 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 362 385 1.1E-18 T 12-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 VAPA_2c05490 2f2f05ed29910b4af49d391a57bf7fbe 429 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 216 227 1.1E-18 T 12-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 VAPA_2c05490 2f2f05ed29910b4af49d391a57bf7fbe 429 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 89 228 5.8E-41 T 12-10-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 VAPA_2c05490 2f2f05ed29910b4af49d391a57bf7fbe 429 Gene3D G3DSA:3.40.50.1370 89 393 1.4E-99 T 12-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 VAPA_2c05490 2f2f05ed29910b4af49d391a57bf7fbe 429 TIGRFAM TIGR00670 asp_carb_tr: aspartate carbamoyltransferase 88 397 7.0E-89 T 12-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 VAPA_2c05490 2f2f05ed29910b4af49d391a57bf7fbe 429 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 240 395 1.4E-26 T 12-10-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 VAPA_2c05490 2f2f05ed29910b4af49d391a57bf7fbe 429 Gene3D G3DSA:3.40.50.1370 216 384 1.4E-99 T 12-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 VAPA_2c05490 2f2f05ed29910b4af49d391a57bf7fbe 429 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 132 139 - T 12-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 VAPA_2c05490 2f2f05ed29910b4af49d391a57bf7fbe 429 SUPERFAMILY SSF53671 88 398 4.32E-87 T 12-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 VAPA_2c05490 2f2f05ed29910b4af49d391a57bf7fbe 429 PRINTS PR00101 Aspartate carbamoyltransferase signature 161 170 8.4E-30 T 12-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 VAPA_2c05490 2f2f05ed29910b4af49d391a57bf7fbe 429 PRINTS PR00101 Aspartate carbamoyltransferase signature 311 320 8.4E-30 T 12-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 VAPA_2c05490 2f2f05ed29910b4af49d391a57bf7fbe 429 PRINTS PR00101 Aspartate carbamoyltransferase signature 215 232 8.4E-30 T 12-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 VAPA_2c05490 2f2f05ed29910b4af49d391a57bf7fbe 429 PRINTS PR00101 Aspartate carbamoyltransferase signature 378 392 8.4E-30 T 12-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 VAPA_2c05490 2f2f05ed29910b4af49d391a57bf7fbe 429 PRINTS PR00101 Aspartate carbamoyltransferase signature 122 144 8.4E-30 T 12-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 VAPA_1c21150 f0c98678226a8406247a0fde73a8d08e 1686 TIGRFAM TIGR02401 trehalose_TreY: malto-oligosyltrehalose synthase 734 1682 1.6E-288 T 12-10-2018 IPR012767 Maltooligosyl trehalose synthase KEGG: 00500+5.4.99.15|MetaCyc: PWY-2661 VAPA_1c21150 f0c98678226a8406247a0fde73a8d08e 1686 TIGRFAM TIGR00217 malQ: 4-alpha-glucanotransferase 125 707 2.8E-152 T 12-10-2018 IPR003385 Glycoside hydrolase, family 77 GO:0004134|GO:0005975 KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238 VAPA_1c21150 f0c98678226a8406247a0fde73a8d08e 1686 SUPERFAMILY SSF51445 733 1581 7.33E-127 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily VAPA_1c21150 f0c98678226a8406247a0fde73a8d08e 1686 SUPERFAMILY SSF51445 151 710 6.08E-149 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily VAPA_1c21150 f0c98678226a8406247a0fde73a8d08e 1686 Gene3D G3DSA:3.20.20.80 737 823 2.7E-17 T 12-10-2018 VAPA_1c21150 f0c98678226a8406247a0fde73a8d08e 1686 Gene3D G3DSA:3.20.20.80 161 708 4.8E-131 T 12-10-2018 VAPA_1c21150 f0c98678226a8406247a0fde73a8d08e 1686 SMART SM00642 744 1206 1.5E-5 T 12-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 VAPA_1c21150 f0c98678226a8406247a0fde73a8d08e 1686 Gene3D G3DSA:3.30.1590.10 824 928 5.3E-23 T 12-10-2018 VAPA_1c21150 f0c98678226a8406247a0fde73a8d08e 1686 Pfam PF00128 Alpha amylase, catalytic domain 755 824 3.0E-12 T 12-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 VAPA_1c21150 f0c98678226a8406247a0fde73a8d08e 1686 Gene3D G3DSA:3.20.20.80 1010 1195 8.8E-32 T 12-10-2018 VAPA_1c21150 f0c98678226a8406247a0fde73a8d08e 1686 Gene3D G3DSA:3.20.20.80 1288 1383 4.6E-7 T 12-10-2018 VAPA_1c21150 f0c98678226a8406247a0fde73a8d08e 1686 Gene3D G3DSA:3.20.20.80 1428 1584 3.8E-36 T 12-10-2018 VAPA_1c21150 f0c98678226a8406247a0fde73a8d08e 1686 Pfam PF02446 4-alpha-glucanotransferase 167 690 5.7E-123 T 12-10-2018 IPR003385 Glycoside hydrolase, family 77 GO:0004134|GO:0005975 KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238 VAPA_1c09010 fbcfcdd646e05b95e5497fc53290814f 271 Gene3D G3DSA:3.90.226.10 6 204 5.5E-58 T 12-10-2018 VAPA_1c09010 fbcfcdd646e05b95e5497fc53290814f 271 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 104 124 - T 12-10-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824 VAPA_1c09010 fbcfcdd646e05b95e5497fc53290814f 271 Gene3D G3DSA:1.10.12.10 206 262 2.2E-11 T 12-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal VAPA_1c09010 fbcfcdd646e05b95e5497fc53290814f 271 Pfam PF00378 Enoyl-CoA hydratase/isomerase 15 261 1.8E-49 T 12-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 VAPA_1c09010 fbcfcdd646e05b95e5497fc53290814f 271 SUPERFAMILY SSF52096 3 261 9.77E-70 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily VAPA_2c01460 caee684660eda720170f392a86f5b91c 234 Gene3D G3DSA:3.50.30.100 3 204 5.6E-58 T 12-10-2018 VAPA_2c01460 caee684660eda720170f392a86f5b91c 234 TIGRFAM TIGR02798 ligK_PcmE: 4-carboxy-4-hydroxy-2-oxoadipate aldolase/oxaloacetate decarboxylase 12 233 5.7E-119 T 12-10-2018 IPR014165 4-carboxy-4-hydroxy-2-oxoadipate aldolase/oxaloacetate decarboxylase KEGG: 00362+4.1.3.17|KEGG: 00660+4.1.3.17|MetaCyc: PWY-7701 VAPA_2c01460 caee684660eda720170f392a86f5b91c 234 Pfam PF03737 Aldolase/RraA 35 182 6.0E-44 T 12-10-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein VAPA_2c01460 caee684660eda720170f392a86f5b91c 234 SUPERFAMILY SSF89562 31 193 2.35E-51 T 12-10-2018 IPR036704 Ribonuclease E inhibitor RraA/RraA-like superfamily VAPA_1c53400 e78fec3b20ae5361b55b7ab5f90110b3 888 SUPERFAMILY SSF52518 500 726 8.1E-92 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold VAPA_1c53400 e78fec3b20ae5361b55b7ab5f90110b3 888 TIGRFAM TIGR03186 AKGDH_not_PDH: alpha-ketoglutarate dehydrogenase 21 887 0.0 T 12-10-2018 IPR017600 Alpha-ketoglutarate dehydrogenase VAPA_1c53400 e78fec3b20ae5361b55b7ab5f90110b3 888 SUPERFAMILY SSF52518 71 492 5.16E-121 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold VAPA_1c53400 e78fec3b20ae5361b55b7ab5f90110b3 888 PIRSF PIRSF000156 11 888 0.0 T 12-10-2018 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 VAPA_1c53400 e78fec3b20ae5361b55b7ab5f90110b3 888 SUPERFAMILY SSF52922 728 887 4.19E-39 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 VAPA_1c53400 e78fec3b20ae5361b55b7ab5f90110b3 888 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 95 325 4.4E-7 T 12-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 VAPA_1c53400 e78fec3b20ae5361b55b7ab5f90110b3 888 TIGRFAM TIGR00759 aceE: pyruvate dehydrogenase (acetyl-transferring), homodimeric type 21 887 0.0 T 12-10-2018 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 VAPA_1c53400 e78fec3b20ae5361b55b7ab5f90110b3 888 Gene3D G3DSA:3.40.50.920 732 888 1.5E-50 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 VAPA_1c53400 e78fec3b20ae5361b55b7ab5f90110b3 888 Gene3D G3DSA:3.40.50.970 70 497 1.3E-123 T 12-10-2018 VAPA_1c53400 e78fec3b20ae5361b55b7ab5f90110b3 888 Gene3D G3DSA:3.40.50.970 498 731 6.6E-105 T 12-10-2018 VAPA_1c51090 94ad3b59f0160f751fb065a3d412dc43 386 Gene3D G3DSA:1.20.58.340 187 323 1.7E-8 T 12-10-2018 VAPA_1c51090 94ad3b59f0160f751fb065a3d412dc43 386 Gene3D G3DSA:1.20.58.340 325 382 3.3E-20 T 12-10-2018 VAPA_1c51090 94ad3b59f0160f751fb065a3d412dc43 386 SUPERFAMILY SSF144083 318 380 1.14E-19 T 12-10-2018 VAPA_1c51090 94ad3b59f0160f751fb065a3d412dc43 386 Pfam PF01544 CorA-like Mg2+ transporter protein 129 378 2.2E-38 T 12-10-2018 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 VAPA_1c51090 94ad3b59f0160f751fb065a3d412dc43 386 SUPERFAMILY SSF143865 6 315 1.11E-13 T 12-10-2018 VAPA_1c02530 ce493043069a85bc4a9f45e6e74e2bdd 522 Pfam PF13005 zinc-finger binding domain of transposase IS66 118 161 1.9E-15 T 12-10-2018 IPR024474 Zinc-finger binding domain of transposase IS66 VAPA_1c02530 ce493043069a85bc4a9f45e6e74e2bdd 522 Pfam PF13817 IS66 C-terminal element 471 508 1.2E-18 T 12-10-2018 IPR039552 Transposase IS66, C-terminal VAPA_1c02530 ce493043069a85bc4a9f45e6e74e2bdd 522 Pfam PF03050 Transposase IS66 family 176 464 3.8E-96 T 12-10-2018 IPR004291 Transposase, IS66 VAPA_1c02530 ce493043069a85bc4a9f45e6e74e2bdd 522 Pfam PF13007 Transposase C of IS166 homeodomain 35 98 8.4E-8 T 12-10-2018 IPR024463 Transposase TnpC, homeodomain VAPA_1c50100 9008c418a0743e81a940ea7552b388a0 130 TIGRFAM TIGR03610 RutC: pyrimidine utilization protein C 1 127 4.6E-76 T 12-10-2018 IPR019898 Putative aminoacrylate peracid reductase RutC VAPA_1c50100 9008c418a0743e81a940ea7552b388a0 130 SUPERFAMILY SSF55298 1 128 5.65E-36 T 12-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 VAPA_1c50100 9008c418a0743e81a940ea7552b388a0 130 Gene3D G3DSA:3.30.1330.40 1 127 1.9E-39 T 12-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 VAPA_1c50100 9008c418a0743e81a940ea7552b388a0 130 Pfam PF01042 Endoribonuclease L-PSP 14 125 7.1E-30 T 12-10-2018 IPR006175 YjgF/YER057c/UK114 family Reactome: R-HSA-8849175 VAPA_1c50100 9008c418a0743e81a940ea7552b388a0 130 Hamap MF_00831 Putative aminoacrylate peracid reductase RutC [rutC]. 1 128 43.058 T 12-10-2018 IPR019898 Putative aminoacrylate peracid reductase RutC VAPA_2c02590 821a762c582904b9584bf3e31a0e4aac 301 SUPERFAMILY SSF161098 94 280 1.24E-18 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_2c02590 821a762c582904b9584bf3e31a0e4aac 301 Gene3D G3DSA:1.10.3720.10 87 291 3.2E-15 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_2c02590 821a762c582904b9584bf3e31a0e4aac 301 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 116 288 1.7E-21 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 VAPA_1c35800 ced125b1561d595591b89d6331b34cc1 291 Gene3D G3DSA:2.60.120.620 1 266 4.1E-84 T 12-10-2018 VAPA_1c35800 ced125b1561d595591b89d6331b34cc1 291 Pfam PF05721 Phytanoyl-CoA dioxygenase (PhyH) 11 221 1.2E-32 T 12-10-2018 IPR008775 Phytanoyl-CoA dioxygenase VAPA_1c35800 ced125b1561d595591b89d6331b34cc1 291 SUPERFAMILY SSF51197 2 263 1.28E-59 T 12-10-2018 VAPA_1c16850 5faa99ab66e6bd5cc96c0a680072aaea 286 Pfam PF12849 PBP superfamily domain 34 261 1.1E-30 T 12-10-2018 IPR024370 PBP domain VAPA_1c16850 5faa99ab66e6bd5cc96c0a680072aaea 286 SUPERFAMILY SSF53850 34 271 7.35E-33 T 12-10-2018 VAPA_1c16850 5faa99ab66e6bd5cc96c0a680072aaea 286 Gene3D G3DSA:3.40.190.10 112 232 4.1E-84 T 12-10-2018 VAPA_1c16850 5faa99ab66e6bd5cc96c0a680072aaea 286 Gene3D G3DSA:3.40.190.10 37 269 4.1E-84 T 12-10-2018 VAPA_2c08230 9d76956a61c30d6443eda7adcfa78616 672 Gene3D G3DSA:3.40.50.300 81 370 2.6E-75 T 12-10-2018 VAPA_2c08230 9d76956a61c30d6443eda7adcfa78616 672 Pfam PF02374 Anion-transporting ATPase 87 368 3.9E-62 T 12-10-2018 IPR025723 Anion-transporting ATPase-like domain Reactome: R-HSA-381038 VAPA_2c08230 9d76956a61c30d6443eda7adcfa78616 672 Pfam PF02374 Anion-transporting ATPase 406 555 3.0E-28 T 12-10-2018 IPR025723 Anion-transporting ATPase-like domain Reactome: R-HSA-381038 VAPA_2c08230 9d76956a61c30d6443eda7adcfa78616 672 SUPERFAMILY SSF52833 2 76 1.46E-13 T 12-10-2018 IPR036249 Thioredoxin-like superfamily VAPA_2c08230 9d76956a61c30d6443eda7adcfa78616 672 PIRSF PIRSF001327 79 664 2.0E-222 T 12-10-2018 IPR027541 Arsenical pump-driving ATPase GO:0005524|GO:0015446|GO:0016887|GO:0071722 MetaCyc: PWY-4621 VAPA_2c08230 9d76956a61c30d6443eda7adcfa78616 672 SUPERFAMILY SSF52540 407 619 7.71E-36 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_2c08230 9d76956a61c30d6443eda7adcfa78616 672 Gene3D G3DSA:3.40.30.10 1 75 1.1E-19 T 12-10-2018 VAPA_2c08230 9d76956a61c30d6443eda7adcfa78616 672 TIGRFAM TIGR04291 arsen_driv_ArsA: arsenical pump-driving ATPase 87 646 1.3E-208 T 12-10-2018 IPR027541 Arsenical pump-driving ATPase GO:0005524|GO:0015446|GO:0016887|GO:0071722 MetaCyc: PWY-4621 VAPA_2c08230 9d76956a61c30d6443eda7adcfa78616 672 SMART SM00382 403 634 0.24 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_2c08230 9d76956a61c30d6443eda7adcfa78616 672 SMART SM00382 86 303 3.0 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_2c08230 9d76956a61c30d6443eda7adcfa78616 672 TIGRFAM TIGR00345 GET3_arsA_TRC40: transport-energizing ATPase, TRC40/GET3/ArsA family 91 368 2.4E-62 T 12-10-2018 IPR016300 Arsenical pump ATPase, ArsA/GET3 GO:0005524|GO:0016887 Reactome: R-HSA-381038 VAPA_2c08230 9d76956a61c30d6443eda7adcfa78616 672 Pfam PF13192 Thioredoxin domain 1 76 2.6E-18 T 12-10-2018 IPR012336 Thioredoxin-like fold VAPA_2c08230 9d76956a61c30d6443eda7adcfa78616 672 SUPERFAMILY SSF52540 85 340 1.21E-45 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_2c08230 9d76956a61c30d6443eda7adcfa78616 672 Gene3D G3DSA:3.40.50.300 389 661 5.6E-59 T 12-10-2018 VAPA_1c50410 0daec5f1ff98011a741a3a4fd64ac2cc 277 Pfam PF00005 ABC transporter 45 184 2.7E-29 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c50410 0daec5f1ff98011a741a3a4fd64ac2cc 277 Gene3D G3DSA:3.40.50.300 28 258 4.0E-59 T 12-10-2018 VAPA_1c50410 0daec5f1ff98011a741a3a4fd64ac2cc 277 SMART SM00382 54 235 4.5E-16 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c50410 0daec5f1ff98011a741a3a4fd64ac2cc 277 SUPERFAMILY SSF52540 30 251 2.88E-58 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c52150 af2224f61ea54dc3875e804bd330848d 340 Pfam PF13407 Periplasmic binding protein domain 25 280 2.0E-59 T 12-10-2018 IPR025997 Periplasmic binding protein VAPA_1c52150 af2224f61ea54dc3875e804bd330848d 340 SUPERFAMILY SSF53822 24 313 2.98E-68 T 12-10-2018 IPR028082 Periplasmic binding protein-like I VAPA_1c52150 af2224f61ea54dc3875e804bd330848d 340 TIGRFAM TIGR02634 xylF: D-xylose ABC transporter, D-xylose-binding protein 25 326 1.3E-124 T 12-10-2018 IPR013456 D-xylose ABC transporter, substrate-binding protein GO:0015753|GO:0048029 VAPA_1c52150 af2224f61ea54dc3875e804bd330848d 340 Gene3D G3DSA:3.40.50.2300 26 302 1.1E-94 T 12-10-2018 VAPA_1c52150 af2224f61ea54dc3875e804bd330848d 340 Gene3D G3DSA:3.40.50.2300 125 313 1.1E-94 T 12-10-2018 VAPA_1c13370 25f761e942f609352a4b4320f4c3e93c 186 Pfam PF14279 HNH endonuclease 91 145 1.5E-15 T 12-10-2018 IPR029471 HNH endonuclease 5 VAPA_1c13370 25f761e942f609352a4b4320f4c3e93c 186 SMART SM00507 78 131 1.1E-9 T 12-10-2018 IPR003615 HNH nuclease VAPA_1c13370 25f761e942f609352a4b4320f4c3e93c 186 Gene3D G3DSA:3.30.40.60 72 156 3.9E-21 T 12-10-2018 VAPA_2c12520 fe0cfbe9a7bc6beb99b2368709ddb91f 350 Gene3D G3DSA:3.40.190.10 133 330 1.2E-79 T 12-10-2018 VAPA_2c12520 fe0cfbe9a7bc6beb99b2368709ddb91f 350 Pfam PF13343 Bacterial extracellular solute-binding protein 109 335 1.9E-28 T 12-10-2018 VAPA_2c12520 fe0cfbe9a7bc6beb99b2368709ddb91f 350 SUPERFAMILY SSF53850 31 347 4.21E-57 T 12-10-2018 VAPA_2c12520 fe0cfbe9a7bc6beb99b2368709ddb91f 350 Gene3D G3DSA:3.40.190.10 38 315 1.2E-79 T 12-10-2018 VAPA_1c11780 56bbc0d4e8cfb177341a49a3d2cf869e 398 Pfam PF03929 PepSY-associated TM region 10 362 1.6E-61 T 12-10-2018 IPR005625 PepSY-associated TM protein VAPA_1c11780 56bbc0d4e8cfb177341a49a3d2cf869e 398 Pfam PF03413 Peptidase propeptide and YPEB domain 60 120 3.7E-5 T 12-10-2018 IPR025711 PepSY domain VAPA_1c14980 e75032ad1b2b121de3361cef13e7aef2 254 Gene3D G3DSA:3.20.20.70 4 254 1.1E-85 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 VAPA_1c14980 e75032ad1b2b121de3361cef13e7aef2 254 Hamap MF_00279 Pyridoxine 5'-phosphate synthase [pdxJ]. 1 254 78.653 T 12-10-2018 IPR004569 Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2 VAPA_1c14980 e75032ad1b2b121de3361cef13e7aef2 254 SUPERFAMILY SSF63892 10 252 8.89E-77 T 12-10-2018 IPR036130 Pyridoxine 5'-phosphate synthase GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2 VAPA_1c14980 e75032ad1b2b121de3361cef13e7aef2 254 TIGRFAM TIGR00559 pdxJ: pyridoxine 5'-phosphate synthase 12 251 4.9E-61 T 12-10-2018 IPR004569 Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2 VAPA_1c14980 e75032ad1b2b121de3361cef13e7aef2 254 Pfam PF03740 Pyridoxal phosphate biosynthesis protein PdxJ 12 250 4.1E-83 T 12-10-2018 IPR004569 Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2 VAPA_1c11930 1936fce78dc9bd0d0068a5b7e6463ed5 438 TIGRFAM TIGR03144 cytochr_II_ccsB: cytochrome c-type biogenesis protein CcsB 143 436 5.9E-77 T 12-10-2018 IPR017562 Cytochrome c-type biogenesis protein CcsA GO:0017004 VAPA_1c11930 1936fce78dc9bd0d0068a5b7e6463ed5 438 Pfam PF01578 Cytochrome C assembly protein 173 433 6.5E-49 T 12-10-2018 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 VAPA_1c17220 a5e06e5fd0f207bd93625edc2b8062c1 90 Pfam PF16082 Bacteriophage holin family, superfamily II-like 1 72 2.7E-25 T 12-10-2018 IPR032124 Bacteriophage F116-like holin VAPA_2c10750 4df0b9d3eae427d88e846cb4b7c3758f 348 SUPERFAMILY SSF89733 13 346 1.83E-103 T 12-10-2018 IPR036111 Malate/L-sulfolactate/L-lactate dehydrogenase-like superfamily GO:0016491|GO:0055114 VAPA_2c10750 4df0b9d3eae427d88e846cb4b7c3758f 348 Gene3D G3DSA:1.10.1530.10 22 346 1.3E-105 T 12-10-2018 VAPA_2c10750 4df0b9d3eae427d88e846cb4b7c3758f 348 Pfam PF02615 Malate/L-lactate dehydrogenase 15 341 1.8E-109 T 12-10-2018 IPR003767 Malate/L-lactate dehydrogenase-like GO:0016491|GO:0055114 VAPA_2c10750 4df0b9d3eae427d88e846cb4b7c3758f 348 Gene3D G3DSA:3.30.1370.60 75 315 1.3E-105 T 12-10-2018 VAPA_1c21930 da6eea8d09f7280e00c896df6bf0ed8f 297 SMART SM01130 3 289 3.1E-101 T 12-10-2018 IPR002220 DapA-like GO:0016829 VAPA_1c21930 da6eea8d09f7280e00c896df6bf0ed8f 297 Pfam PF00701 Dihydrodipicolinate synthetase family 4 277 7.8E-59 T 12-10-2018 IPR002220 DapA-like GO:0016829 VAPA_1c21930 da6eea8d09f7280e00c896df6bf0ed8f 297 SUPERFAMILY SSF51569 2 290 1.88E-87 T 12-10-2018 VAPA_1c21930 da6eea8d09f7280e00c896df6bf0ed8f 297 PRINTS PR00146 Dihydrodipicolinate synthase signature 73 91 4.2E-17 T 12-10-2018 IPR002220 DapA-like GO:0016829 VAPA_1c21930 da6eea8d09f7280e00c896df6bf0ed8f 297 PRINTS PR00146 Dihydrodipicolinate synthase signature 105 121 4.2E-17 T 12-10-2018 IPR002220 DapA-like GO:0016829 VAPA_1c21930 da6eea8d09f7280e00c896df6bf0ed8f 297 PRINTS PR00146 Dihydrodipicolinate synthase signature 37 58 4.2E-17 T 12-10-2018 IPR002220 DapA-like GO:0016829 VAPA_1c21930 da6eea8d09f7280e00c896df6bf0ed8f 297 PRINTS PR00146 Dihydrodipicolinate synthase signature 130 147 4.2E-17 T 12-10-2018 IPR002220 DapA-like GO:0016829 VAPA_1c21930 da6eea8d09f7280e00c896df6bf0ed8f 297 Hamap MF_00418 4-hydroxy-tetrahydrodipicolinate synthase [dapA]. 3 287 39.68 T 12-10-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 VAPA_1c21930 da6eea8d09f7280e00c896df6bf0ed8f 297 Gene3D G3DSA:3.20.20.70 1 293 2.5E-92 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 VAPA_1c21930 da6eea8d09f7280e00c896df6bf0ed8f 297 ProSitePatterns PS00665 Dihydrodipicolinate synthase signature 1. 40 57 - T 12-10-2018 IPR020624 Schiff base-forming aldolase, conserved site GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 VAPA_1c21930 da6eea8d09f7280e00c896df6bf0ed8f 297 PIRSF PIRSF001365 1 297 2.0E-82 T 12-10-2018 IPR002220 DapA-like GO:0016829 VAPA_2c00020 ca6d87cf63d3e3165af9d965e53ea517 299 Pfam PF08535 KorB domain 144 212 1.5E-12 T 12-10-2018 IPR013741 Repressor KorB domain VAPA_2c00020 ca6d87cf63d3e3165af9d965e53ea517 299 SUPERFAMILY SSF110849 34 172 5.23E-19 T 12-10-2018 IPR036086 ParB/Sulfiredoxin superfamily VAPA_2c00020 ca6d87cf63d3e3165af9d965e53ea517 299 SMART SM00470 34 123 7.0E-14 T 12-10-2018 IPR003115 ParB/Sulfiredoxin VAPA_2c00020 ca6d87cf63d3e3165af9d965e53ea517 299 TIGRFAM TIGR00180 parB_part: ParB/RepB/Spo0J family partition protein 33 204 7.4E-34 T 12-10-2018 IPR004437 ParB/RepB/Spo0J partition protein family GO:0003677 VAPA_2c00020 ca6d87cf63d3e3165af9d965e53ea517 299 Pfam PF02195 ParB-like nuclease domain 35 111 1.7E-15 T 12-10-2018 IPR003115 ParB/Sulfiredoxin VAPA_2c00020 ca6d87cf63d3e3165af9d965e53ea517 299 Gene3D G3DSA:1.10.10.730 116 169 1.8E-14 T 12-10-2018 VAPA_2c00020 ca6d87cf63d3e3165af9d965e53ea517 299 Gene3D G3DSA:3.90.1530.30 47 111 2.5E-18 T 12-10-2018 VAPA_1c12530 e8c327f42c88af807b80d379fae84442 355 Gene3D G3DSA:3.40.50.2000 177 338 1.1E-41 T 12-10-2018 VAPA_1c12530 e8c327f42c88af807b80d379fae84442 355 Pfam PF00534 Glycosyl transferases group 1 185 331 2.2E-32 T 12-10-2018 IPR001296 Glycosyl transferase, family 1 VAPA_1c12530 e8c327f42c88af807b80d379fae84442 355 Pfam PF13439 Glycosyltransferase Family 4 52 170 5.1E-14 T 12-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 VAPA_1c12530 e8c327f42c88af807b80d379fae84442 355 Gene3D G3DSA:3.40.50.2000 1 176 3.1E-16 T 12-10-2018 VAPA_1c12530 e8c327f42c88af807b80d379fae84442 355 SUPERFAMILY SSF53756 51 352 6.67E-70 T 12-10-2018 VAPA_1c43760 acb6f1e43fb342766705b610c3a7cc75 330 SUPERFAMILY SSF48576 9 329 4.8E-98 T 12-10-2018 IPR008949 Isoprenoid synthase domain superfamily VAPA_1c43760 acb6f1e43fb342766705b610c3a7cc75 330 Gene3D G3DSA:1.10.600.10 3 329 5.4E-110 T 12-10-2018 IPR008949 Isoprenoid synthase domain superfamily VAPA_1c43760 acb6f1e43fb342766705b610c3a7cc75 330 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 89 103 - T 12-10-2018 IPR033749 Polyprenyl synthetase, conserved site VAPA_1c43760 acb6f1e43fb342766705b610c3a7cc75 330 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 211 223 - T 12-10-2018 IPR033749 Polyprenyl synthetase, conserved site VAPA_1c43760 acb6f1e43fb342766705b610c3a7cc75 330 Pfam PF00348 Polyprenyl synthetase 39 282 7.7E-77 T 12-10-2018 IPR000092 Polyprenyl synthetase GO:0008299 VAPA_1c30790 1ab857a0c784858b288345cf76262c9f 268 Gene3D G3DSA:3.40.50.300 1 267 8.3E-102 T 12-10-2018 VAPA_1c30790 1ab857a0c784858b288345cf76262c9f 268 Pfam PF03976 Polyphosphate kinase 2 (PPK2) 31 252 8.1E-69 T 12-10-2018 IPR022488 Polyphosphate kinase-2-related VAPA_1c30790 1ab857a0c784858b288345cf76262c9f 268 TIGRFAM TIGR03709 PPK2_rel_1: polyphosphate:nucleotide phosphotransferase, PPK2 family 9 263 1.5E-102 T 12-10-2018 IPR022300 Polyphosphate:nucleotide phosphotransferase, PPK2 GO:0006797|GO:0016776 KEGG: 00190+2.7.4.1 VAPA_1c30790 1ab857a0c784858b288345cf76262c9f 268 SUPERFAMILY SSF52540 60 235 2.19E-14 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c30790 1ab857a0c784858b288345cf76262c9f 268 PIRSF PIRSF028756 4 265 3.3E-75 T 12-10-2018 IPR016898 Polyphosphate kinase 2 KEGG: 00190+2.7.4.1 VAPA_1c18310 33901a21b29433248ff80be7451048b1 221 SUPERFAMILY SSF52833 2 90 1.42E-19 T 12-10-2018 IPR036249 Thioredoxin-like superfamily VAPA_1c18310 33901a21b29433248ff80be7451048b1 221 SUPERFAMILY SSF47616 80 203 8.63E-22 T 12-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily VAPA_1c18310 33901a21b29433248ff80be7451048b1 221 Pfam PF00043 Glutathione S-transferase, C-terminal domain 135 195 6.7E-6 T 12-10-2018 IPR004046 Glutathione S-transferase, C-terminal VAPA_1c18310 33901a21b29433248ff80be7451048b1 221 Pfam PF13417 Glutathione S-transferase, N-terminal domain 6 84 4.5E-14 T 12-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 VAPA_1c18310 33901a21b29433248ff80be7451048b1 221 Gene3D G3DSA:1.20.1050.10 88 194 3.9E-40 T 12-10-2018 VAPA_1c18310 33901a21b29433248ff80be7451048b1 221 Gene3D G3DSA:3.40.30.10 6 197 3.9E-40 T 12-10-2018 VAPA_1c52700 bfb011e7b260d88ca28cfd9389c6d7db 652 Pfam PF07690 Major Facilitator Superfamily 36 348 2.2E-11 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 VAPA_1c52700 bfb011e7b260d88ca28cfd9389c6d7db 652 Gene3D G3DSA:1.20.1250.20 27 441 3.9E-26 T 12-10-2018 VAPA_1c52700 bfb011e7b260d88ca28cfd9389c6d7db 652 Pfam PF01553 Acyltransferase 459 590 4.1E-27 T 12-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 VAPA_1c52700 bfb011e7b260d88ca28cfd9389c6d7db 652 SUPERFAMILY SSF103473 27 443 6.02E-29 T 12-10-2018 IPR036259 MFS transporter superfamily VAPA_1c52700 bfb011e7b260d88ca28cfd9389c6d7db 652 SUPERFAMILY SSF69593 421 629 9.55E-33 T 12-10-2018 VAPA_1c52700 bfb011e7b260d88ca28cfd9389c6d7db 652 SMART SM00563 473 594 2.0E-34 T 12-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 VAPA_1c48530 691b360956ba3a039d43269d2de75ebf 272 SUPERFAMILY SSF161098 15 271 1.44E-58 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c48530 691b360956ba3a039d43269d2de75ebf 272 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 91 267 3.3E-15 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 VAPA_1c48530 691b360956ba3a039d43269d2de75ebf 272 Gene3D G3DSA:1.10.3720.10 19 272 7.8E-54 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c15660 ba5d6d0325db57f4982805ee0cf79834 184 Hamap MF_00014 Ribosome maturation factor RimM [rimM]. 14 184 23.167 T 12-10-2018 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 VAPA_1c15660 ba5d6d0325db57f4982805ee0cf79834 184 Gene3D G3DSA:2.30.30.240 107 184 4.8E-25 T 12-10-2018 VAPA_1c15660 ba5d6d0325db57f4982805ee0cf79834 184 SUPERFAMILY SSF50346 111 184 7.59E-17 T 12-10-2018 IPR011033 PRC-barrel-like superfamily VAPA_1c15660 ba5d6d0325db57f4982805ee0cf79834 184 TIGRFAM TIGR02273 16S_RimM: 16S rRNA processing protein RimM 15 183 2.0E-42 T 12-10-2018 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 VAPA_1c15660 ba5d6d0325db57f4982805ee0cf79834 184 SUPERFAMILY SSF50447 13 104 2.82E-19 T 12-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily VAPA_1c15660 ba5d6d0325db57f4982805ee0cf79834 184 Pfam PF01782 RimM N-terminal domain 16 101 1.2E-24 T 12-10-2018 IPR002676 RimM, N-terminal GO:0006364 VAPA_1c15660 ba5d6d0325db57f4982805ee0cf79834 184 Pfam PF05239 PRC-barrel domain 109 179 2.3E-6 T 12-10-2018 IPR027275 PRC-barrel domain VAPA_1c15660 ba5d6d0325db57f4982805ee0cf79834 184 Gene3D G3DSA:2.40.30.60 5 105 1.9E-28 T 12-10-2018 IPR036976 RimM, N-terminal domain superfamily GO:0006364 VAPA_1c40190 86ec43f3953def4ae3f1acae66be3d92 298 Gene3D G3DSA:1.10.10.10 1 82 8.1E-23 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c40190 86ec43f3953def4ae3f1acae66be3d92 298 Gene3D G3DSA:3.40.190.10 164 262 1.0E-35 T 12-10-2018 VAPA_1c40190 86ec43f3953def4ae3f1acae66be3d92 298 SUPERFAMILY SSF46785 3 109 2.33E-22 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c40190 86ec43f3953def4ae3f1acae66be3d92 298 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 61 2.7E-18 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c40190 86ec43f3953def4ae3f1acae66be3d92 298 Gene3D G3DSA:3.40.190.10 89 273 1.0E-35 T 12-10-2018 VAPA_1c40190 86ec43f3953def4ae3f1acae66be3d92 298 Pfam PF03466 LysR substrate binding domain 86 285 8.1E-36 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_1c40190 86ec43f3953def4ae3f1acae66be3d92 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 6.4E-5 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c40190 86ec43f3953def4ae3f1acae66be3d92 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 6.4E-5 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c40190 86ec43f3953def4ae3f1acae66be3d92 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 6.4E-5 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c40190 86ec43f3953def4ae3f1acae66be3d92 298 SUPERFAMILY SSF53850 88 287 1.55E-33 T 12-10-2018 VAPA_1c54080 a8a098c41399d884ca6775bc58982fb6 274 TIGRFAM TIGR00121 birA_ligase: biotin--[acetyl-CoA-carboxylase] ligase 26 266 4.1E-39 T 12-10-2018 IPR004408 Biotin--acetyl-CoA-carboxylase ligase GO:0004077|GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 VAPA_1c54080 a8a098c41399d884ca6775bc58982fb6 274 Gene3D G3DSA:2.30.30.100 226 271 8.5E-6 T 12-10-2018 VAPA_1c54080 a8a098c41399d884ca6775bc58982fb6 274 SUPERFAMILY SSF55681 15 222 7.58E-41 T 12-10-2018 VAPA_1c54080 a8a098c41399d884ca6775bc58982fb6 274 Pfam PF03099 Biotin/lipoate A/B protein ligase family 47 140 4.4E-10 T 12-10-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 VAPA_1c54080 a8a098c41399d884ca6775bc58982fb6 274 Gene3D G3DSA:3.30.930.10 13 224 4.0E-49 T 12-10-2018 VAPA_1c34340 efce5f1df104ca2f7b3672f2be524884 221 Pfam PF00486 Transcriptional regulatory protein, C terminal 145 218 2.2E-19 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 VAPA_1c34340 efce5f1df104ca2f7b3672f2be524884 221 Gene3D G3DSA:3.40.50.2300 1 121 9.6E-33 T 12-10-2018 VAPA_1c34340 efce5f1df104ca2f7b3672f2be524884 221 SUPERFAMILY SSF52172 1 167 1.61E-34 T 12-10-2018 IPR011006 CheY-like superfamily VAPA_1c34340 efce5f1df104ca2f7b3672f2be524884 221 SMART SM00448 1 112 9.6E-34 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_1c34340 efce5f1df104ca2f7b3672f2be524884 221 SMART SM00862 145 218 1.3E-18 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 VAPA_1c34340 efce5f1df104ca2f7b3672f2be524884 221 Gene3D G3DSA:1.10.10.10 124 221 2.7E-25 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c34340 efce5f1df104ca2f7b3672f2be524884 221 Pfam PF00072 Response regulator receiver domain 3 112 3.3E-23 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_1c16540 2c33d6852ce38ce8651b0122eb843270 248 SUPERFAMILY SSF47413 20 87 3.1E-15 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 VAPA_1c16540 2c33d6852ce38ce8651b0122eb843270 248 Pfam PF07883 Cupin domain 147 197 1.8E-12 T 12-10-2018 IPR013096 Cupin 2, conserved barrel VAPA_1c16540 2c33d6852ce38ce8651b0122eb843270 248 Pfam PF13560 Helix-turn-helix domain 25 79 1.3E-12 T 12-10-2018 VAPA_1c16540 2c33d6852ce38ce8651b0122eb843270 248 SMART SM00530 28 83 3.1E-10 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 VAPA_1c16540 2c33d6852ce38ce8651b0122eb843270 248 SUPERFAMILY SSF51182 94 200 3.52E-25 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily VAPA_1c16540 2c33d6852ce38ce8651b0122eb843270 248 Gene3D G3DSA:2.60.120.10 100 202 2.6E-24 T 12-10-2018 IPR014710 RmlC-like jelly roll fold VAPA_1c16540 2c33d6852ce38ce8651b0122eb843270 248 Gene3D G3DSA:1.10.260.40 11 87 5.1E-15 T 12-10-2018 VAPA_2c12070 dff32be2653d269f1c43992728f6293d 123 Gene3D G3DSA:3.30.1330.40 8 123 8.2E-28 T 12-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 VAPA_2c12070 dff32be2653d269f1c43992728f6293d 123 SUPERFAMILY SSF55298 10 123 6.28E-29 T 12-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 VAPA_2c12070 dff32be2653d269f1c43992728f6293d 123 Pfam PF01042 Endoribonuclease L-PSP 14 122 5.4E-22 T 12-10-2018 IPR006175 YjgF/YER057c/UK114 family Reactome: R-HSA-8849175 VAPA_1c48620 0d50cf9f3e9e88875667b741fdede05f 88 Pfam PF06945 Protein of unknown function (DUF1289) 25 71 4.9E-19 T 12-10-2018 IPR010710 Protein of unknown function DUF1289 VAPA_1c39660 590cd4a5b30079b8eb1e71715866fbaa 350 SUPERFAMILY SSF52540 6 256 3.94E-71 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c39660 590cd4a5b30079b8eb1e71715866fbaa 350 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 237 308 2.0E-15 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 VAPA_1c39660 590cd4a5b30079b8eb1e71715866fbaa 350 Pfam PF00005 ABC transporter 26 185 3.1E-29 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c39660 590cd4a5b30079b8eb1e71715866fbaa 350 SMART SM00382 35 235 1.2E-18 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c39660 590cd4a5b30079b8eb1e71715866fbaa 350 Gene3D G3DSA:3.40.50.300 4 349 2.9E-103 T 12-10-2018 VAPA_1c39660 590cd4a5b30079b8eb1e71715866fbaa 350 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 235 315 1.2E-18 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 VAPA_1c39660 590cd4a5b30079b8eb1e71715866fbaa 350 ProSitePatterns PS00211 ABC transporters family signature. 158 172 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_1c30200 641fa45ffd195430566e5d95ac52266d 257 Gene3D G3DSA:3.40.50.720 1 257 8.9E-67 T 12-10-2018 VAPA_1c30200 641fa45ffd195430566e5d95ac52266d 257 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 146 174 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 VAPA_1c30200 641fa45ffd195430566e5d95ac52266d 257 SUPERFAMILY SSF51735 7 256 2.2E-57 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c30200 641fa45ffd195430566e5d95ac52266d 257 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 19 255 1.0E-44 T 12-10-2018 VAPA_1c30200 641fa45ffd195430566e5d95ac52266d 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 88 99 3.4E-8 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c30200 641fa45ffd195430566e5d95ac52266d 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 139 147 3.4E-8 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c30200 641fa45ffd195430566e5d95ac52266d 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 159 178 3.4E-8 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c30200 641fa45ffd195430566e5d95ac52266d 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 5.9E-22 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c30200 641fa45ffd195430566e5d95ac52266d 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 180 197 5.9E-22 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c30200 641fa45ffd195430566e5d95ac52266d 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 219 239 5.9E-22 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c30200 641fa45ffd195430566e5d95ac52266d 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 88 99 5.9E-22 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c30200 641fa45ffd195430566e5d95ac52266d 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 159 178 5.9E-22 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c30200 641fa45ffd195430566e5d95ac52266d 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 133 149 5.9E-22 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c23650 c55cca51a3b7bbff86d7514910c5b786 284 SMART SM00028 100 133 1.2E-5 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 VAPA_1c23650 c55cca51a3b7bbff86d7514910c5b786 284 SMART SM00028 134 167 130.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 VAPA_1c23650 c55cca51a3b7bbff86d7514910c5b786 284 SMART SM00028 170 203 7.5 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 VAPA_1c23650 c55cca51a3b7bbff86d7514910c5b786 284 SMART SM00028 66 99 47.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 VAPA_1c23650 c55cca51a3b7bbff86d7514910c5b786 284 Pfam PF13414 TPR repeat 76 113 1.8E-6 T 12-10-2018 VAPA_1c23650 c55cca51a3b7bbff86d7514910c5b786 284 TIGRFAM TIGR02521 type_IV_pilW: type IV pilus biogenesis/stability protein PilW 23 269 2.1E-63 T 12-10-2018 IPR013360 Pilus biogenesis/stability type IV, PilW VAPA_1c23650 c55cca51a3b7bbff86d7514910c5b786 284 SUPERFAMILY SSF48452 73 242 2.7E-25 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 VAPA_1c23650 c55cca51a3b7bbff86d7514910c5b786 284 Pfam PF13431 Tetratricopeptide repeat 123 153 2.8E-6 T 12-10-2018 VAPA_1c23650 c55cca51a3b7bbff86d7514910c5b786 284 Gene3D G3DSA:1.25.40.10 60 280 2.9E-49 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 VAPA_2c12930 644eae3fb953e39399ee345a756ff6ad 91 Gene3D G3DSA:1.20.1250.110 5 91 2.8E-17 T 12-10-2018 VAPA_1c05870 01a3f6a9911d86cc81059b2db438aa75 667 SMART SM00304 209 275 2.5E-4 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 VAPA_1c05870 01a3f6a9911d86cc81059b2db438aa75 667 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 410 523 1.5E-21 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase VAPA_1c05870 01a3f6a9911d86cc81059b2db438aa75 667 SUPERFAMILY SSF55874 354 525 2.49E-38 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_1c05870 01a3f6a9911d86cc81059b2db438aa75 667 SUPERFAMILY SSF52172 544 661 4.27E-22 T 12-10-2018 IPR011006 CheY-like superfamily VAPA_1c05870 01a3f6a9911d86cc81059b2db438aa75 667 SMART SM00448 545 658 1.6E-16 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_1c05870 01a3f6a9911d86cc81059b2db438aa75 667 Pfam PF00512 His Kinase A (phospho-acceptor) domain 301 364 3.4E-10 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 VAPA_1c05870 01a3f6a9911d86cc81059b2db438aa75 667 Gene3D G3DSA:3.30.565.10 373 530 2.6E-37 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_1c05870 01a3f6a9911d86cc81059b2db438aa75 667 Gene3D G3DSA:3.40.50.2300 542 666 1.3E-20 T 12-10-2018 VAPA_1c05870 01a3f6a9911d86cc81059b2db438aa75 667 Pfam PF00072 Response regulator receiver domain 548 658 7.1E-14 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_1c05870 01a3f6a9911d86cc81059b2db438aa75 667 Gene3D G3DSA:1.10.287.130 207 361 1.2E-14 T 12-10-2018 VAPA_1c05870 01a3f6a9911d86cc81059b2db438aa75 667 SUPERFAMILY SSF47384 289 364 2.35E-12 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 VAPA_1c05870 01a3f6a9911d86cc81059b2db438aa75 667 SMART SM00388 301 365 1.1E-12 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 VAPA_1c05870 01a3f6a9911d86cc81059b2db438aa75 667 SMART SM00387 409 525 5.1E-34 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase VAPA_1c05870 01a3f6a9911d86cc81059b2db438aa75 667 PRINTS PR00344 Bacterial sensor protein C-terminal signature 485 503 2.4E-12 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c05870 01a3f6a9911d86cc81059b2db438aa75 667 PRINTS PR00344 Bacterial sensor protein C-terminal signature 468 478 2.4E-12 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c05870 01a3f6a9911d86cc81059b2db438aa75 667 PRINTS PR00344 Bacterial sensor protein C-terminal signature 509 522 2.4E-12 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c05870 01a3f6a9911d86cc81059b2db438aa75 667 PRINTS PR00344 Bacterial sensor protein C-terminal signature 450 464 2.4E-12 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c17350 2a43565e4e939d5b16155a666076c1c9 324 Pfam PF04116 Fatty acid hydroxylase superfamily 135 278 3.4E-30 T 12-10-2018 IPR006694 Fatty acid hydroxylase GO:0005506|GO:0008610|GO:0016491|GO:0055114 VAPA_2c05620 4c49ba9a073f1fd944b33e55bac4f0b2 311 SUPERFAMILY SSF48008 184 308 2.33E-9 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal VAPA_2c05620 4c49ba9a073f1fd944b33e55bac4f0b2 311 Gene3D G3DSA:2.30.110.10 10 178 2.5E-54 T 12-10-2018 IPR012349 FMN-binding split barrel GO:0048037 VAPA_2c05620 4c49ba9a073f1fd944b33e55bac4f0b2 311 Pfam PF07729 FCD domain 187 305 2.1E-11 T 12-10-2018 IPR011711 GntR, C-terminal VAPA_2c05620 4c49ba9a073f1fd944b33e55bac4f0b2 311 SMART SM00903 21 166 1.3E-61 T 12-10-2018 IPR002563 Flavin reductase like domain GO:0010181 VAPA_2c05620 4c49ba9a073f1fd944b33e55bac4f0b2 311 SMART SM00895 184 307 1.8E-7 T 12-10-2018 IPR011711 GntR, C-terminal VAPA_2c05620 4c49ba9a073f1fd944b33e55bac4f0b2 311 Gene3D G3DSA:1.20.120.530 182 310 5.2E-11 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal VAPA_2c05620 4c49ba9a073f1fd944b33e55bac4f0b2 311 SUPERFAMILY SSF50475 12 166 3.58E-49 T 12-10-2018 VAPA_2c05620 4c49ba9a073f1fd944b33e55bac4f0b2 311 Pfam PF01613 Flavin reductase like domain 22 165 1.4E-40 T 12-10-2018 IPR002563 Flavin reductase like domain GO:0010181 VAPA_1c14080 3c8e2211b8d141cb359d1799a120e9b0 196 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 12 25 9.5E-7 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 VAPA_1c14080 3c8e2211b8d141cb359d1799a120e9b0 196 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 56 9.5E-7 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 VAPA_1c14080 3c8e2211b8d141cb359d1799a120e9b0 196 Pfam PF00440 Bacterial regulatory proteins, tetR family 12 57 8.9E-14 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 VAPA_1c14080 3c8e2211b8d141cb359d1799a120e9b0 196 Gene3D G3DSA:1.10.357.10 5 193 3.1E-52 T 12-10-2018 VAPA_1c14080 3c8e2211b8d141cb359d1799a120e9b0 196 SUPERFAMILY SSF46689 4 75 1.13E-17 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 VAPA_1c14080 3c8e2211b8d141cb359d1799a120e9b0 196 SUPERFAMILY SSF48498 85 187 5.34E-11 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily VAPA_1c43200 4010db6cb0e540b01a793fb9e2426a4f 140 TIGRFAM TIGR00208 fliS: flagellar protein FliS 10 133 4.0E-28 T 12-10-2018 IPR003713 Flagellar protein FliS GO:0044780 VAPA_1c43200 4010db6cb0e540b01a793fb9e2426a4f 140 Pfam PF02561 Flagellar protein FliS 12 133 2.3E-33 T 12-10-2018 IPR003713 Flagellar protein FliS GO:0044780 VAPA_1c43200 4010db6cb0e540b01a793fb9e2426a4f 140 Gene3D G3DSA:1.20.120.340 5 136 1.9E-33 T 12-10-2018 VAPA_1c43200 4010db6cb0e540b01a793fb9e2426a4f 140 PIRSF PIRSF039090 6 139 7.2E-35 T 12-10-2018 IPR003713 Flagellar protein FliS GO:0044780 VAPA_1c43200 4010db6cb0e540b01a793fb9e2426a4f 140 SUPERFAMILY SSF101116 13 133 1.7E-32 T 12-10-2018 IPR036584 Flagellar protein FliS superfamily GO:0044780 VAPA_1c54550 f252c29e7de0c167eca999ff2de5ace0 260 SUPERFAMILY SSF52540 7 251 3.51E-75 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c54550 f252c29e7de0c167eca999ff2de5ace0 260 SMART SM00382 32 228 2.5E-14 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c54550 f252c29e7de0c167eca999ff2de5ace0 260 PIRSF PIRSF039085 4 257 5.5E-108 T 12-10-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 VAPA_1c54550 f252c29e7de0c167eca999ff2de5ace0 260 Gene3D G3DSA:3.40.50.300 5 259 1.3E-75 T 12-10-2018 VAPA_1c54550 f252c29e7de0c167eca999ff2de5ace0 260 Pfam PF00005 ABC transporter 23 181 2.2E-33 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c54550 f252c29e7de0c167eca999ff2de5ace0 260 ProSitePatterns PS00211 ABC transporters family signature. 153 167 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_2c04170 9a6ddf80a484ba06a94d9846410ec3f2 216 Gene3D G3DSA:3.30.1310.20 56 114 1.0E-17 T 12-10-2018 VAPA_2c04170 9a6ddf80a484ba06a94d9846410ec3f2 216 SUPERFAMILY SSF53271 1 207 1.44E-43 T 12-10-2018 IPR029057 Phosphoribosyltransferase-like VAPA_2c04170 9a6ddf80a484ba06a94d9846410ec3f2 216 Pfam PF00156 Phosphoribosyl transferase domain 6 193 1.2E-33 T 12-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 VAPA_1c36810 7047b5463ef8c5cbb16038152361c73d 157 Gene3D G3DSA:1.10.1660.10 1 125 5.6E-35 T 12-10-2018 VAPA_1c36810 7047b5463ef8c5cbb16038152361c73d 157 SMART SM00422 1 70 4.9E-28 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 VAPA_1c36810 7047b5463ef8c5cbb16038152361c73d 157 TIGRFAM TIGR02047 CadR-PbrR: Cd(II)/Pb(II)-responsive transcriptional regulator 1 127 5.5E-55 T 12-10-2018 IPR011791 Cd(II)/Pb(II)-responsive transcriptional regulator GO:0003677|GO:0003700|GO:0045893|GO:0046872 VAPA_1c36810 7047b5463ef8c5cbb16038152361c73d 157 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 6.1E-8 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 VAPA_1c36810 7047b5463ef8c5cbb16038152361c73d 157 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 37 57 6.1E-8 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 VAPA_1c36810 7047b5463ef8c5cbb16038152361c73d 157 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 6.1E-8 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 VAPA_1c36810 7047b5463ef8c5cbb16038152361c73d 157 SUPERFAMILY SSF46955 1 125 6.59E-36 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily VAPA_1c36810 7047b5463ef8c5cbb16038152361c73d 157 Pfam PF13411 MerR HTH family regulatory protein 1 68 2.2E-20 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 VAPA_1c53210 39f759872639ec9eff85104ae8368f8f 386 PRINTS PR01166 Cytochrome c oxidase subunit II signature 111 130 6.1E-9 T 12-10-2018 VAPA_1c53210 39f759872639ec9eff85104ae8368f8f 386 PRINTS PR01166 Cytochrome c oxidase subunit II signature 225 242 6.1E-9 T 12-10-2018 VAPA_1c53210 39f759872639ec9eff85104ae8368f8f 386 PRINTS PR01166 Cytochrome c oxidase subunit II signature 163 184 6.1E-9 T 12-10-2018 VAPA_1c53210 39f759872639ec9eff85104ae8368f8f 386 PRINTS PR01166 Cytochrome c oxidase subunit II signature 187 207 6.1E-9 T 12-10-2018 VAPA_1c53210 39f759872639ec9eff85104ae8368f8f 386 Gene3D G3DSA:2.60.40.420 111 252 1.8E-55 T 12-10-2018 IPR008972 Cupredoxin VAPA_1c53210 39f759872639ec9eff85104ae8368f8f 386 Gene3D G3DSA:1.10.760.10 278 371 5.6E-30 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 VAPA_1c53210 39f759872639ec9eff85104ae8368f8f 386 ProSitePatterns PS00078 CO II and nitrous oxide reductase dinuclear copper centers signature. 188 236 - T 12-10-2018 IPR001505 Copper centre Cu(A) GO:0005507 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 VAPA_1c53210 39f759872639ec9eff85104ae8368f8f 386 Pfam PF00034 Cytochrome c 282 371 1.2E-10 T 12-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 VAPA_1c53210 39f759872639ec9eff85104ae8368f8f 386 SUPERFAMILY SSF46626 281 371 7.09E-19 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 VAPA_1c53210 39f759872639ec9eff85104ae8368f8f 386 SUPERFAMILY SSF49503 111 254 6.71E-41 T 12-10-2018 IPR008972 Cupredoxin VAPA_1c53210 39f759872639ec9eff85104ae8368f8f 386 Gene3D G3DSA:1.10.287.90 41 110 1.8E-55 T 12-10-2018 IPR036257 Cytochrome C oxidase subunit II, transmembrane domain superfamily Reactome: R-HSA-5628897|Reactome: R-HSA-611105 VAPA_1c53210 39f759872639ec9eff85104ae8368f8f 386 Pfam PF00116 Cytochrome C oxidase subunit II, periplasmic domain 116 237 3.7E-14 T 12-10-2018 IPR002429 Cytochrome c oxidase subunit II-like C-terminal GO:0004129|GO:0005507|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 VAPA_2c09170 a722cc1b1aeb79744c885659b1f01250 625 SUPERFAMILY SSF53474 59 358 1.78E-42 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_2c09170 a722cc1b1aeb79744c885659b1f01250 625 SMART SM00939 337 593 1.1E-23 T 12-10-2018 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 VAPA_2c09170 a722cc1b1aeb79744c885659b1f01250 625 Gene3D G3DSA:2.60.120.260 396 601 4.5E-34 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily VAPA_2c09170 a722cc1b1aeb79744c885659b1f01250 625 Pfam PF02129 X-Pro dipeptidyl-peptidase (S15 family) 64 321 2.4E-31 T 12-10-2018 IPR000383 Xaa-Pro dipeptidyl-peptidase-like domain GO:0016787 VAPA_2c09170 a722cc1b1aeb79744c885659b1f01250 625 Pfam PF08530 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain 443 592 1.9E-27 T 12-10-2018 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 VAPA_2c09170 a722cc1b1aeb79744c885659b1f01250 625 TIGRFAM TIGR00976 /NonD: hydrolase CocE/NonD family protein 62 353 2.4E-33 T 12-10-2018 IPR005674 CocE/Serine esterase GO:0016787 VAPA_2c09170 a722cc1b1aeb79744c885659b1f01250 625 SUPERFAMILY SSF49785 397 597 2.55E-31 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily VAPA_2c11800 3a202b89a54c13db8409a4edbab12f00 216 Gene3D G3DSA:3.40.50.300 6 208 3.6E-33 T 12-10-2018 VAPA_2c11800 3a202b89a54c13db8409a4edbab12f00 216 Pfam PF00005 ABC transporter 37 164 4.2E-17 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_2c11800 3a202b89a54c13db8409a4edbab12f00 216 SUPERFAMILY SSF52540 5 196 1.71E-30 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_2c11800 3a202b89a54c13db8409a4edbab12f00 216 SMART SM00382 34 206 1.2E-5 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c48390 d0d0fc6842848090ae1132f54b44e680 113 Gene3D G3DSA:1.10.260.40 14 88 4.9E-14 T 12-10-2018 VAPA_1c48390 d0d0fc6842848090ae1132f54b44e680 113 SUPERFAMILY SSF47413 18 75 4.29E-9 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 VAPA_1c48390 d0d0fc6842848090ae1132f54b44e680 113 Pfam PF13560 Helix-turn-helix domain 21 78 2.6E-8 T 12-10-2018 VAPA_1c48390 d0d0fc6842848090ae1132f54b44e680 113 SMART SM00530 25 80 0.0057 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 VAPA_2c07630 bc5a2ba11ba326ccb55f561c71dc5468 329 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 53 323 8.8E-87 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_2c07630 bc5a2ba11ba326ccb55f561c71dc5468 329 PIRSF PIRSF017082 1 328 1.5E-80 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_2c07630 bc5a2ba11ba326ccb55f561c71dc5468 329 Gene3D G3DSA:3.40.190.150 34 319 1.5E-114 T 12-10-2018 VAPA_2c07630 bc5a2ba11ba326ccb55f561c71dc5468 329 Gene3D G3DSA:3.40.190.10 131 254 1.5E-114 T 12-10-2018 VAPA_2c07630 bc5a2ba11ba326ccb55f561c71dc5468 329 SUPERFAMILY SSF53850 119 291 1.24E-13 T 12-10-2018 VAPA_2c08010 780b40982051ef3cf96a204859861e85 307 Gene3D G3DSA:3.40.50.720 115 286 4.1E-99 T 12-10-2018 VAPA_2c08010 780b40982051ef3cf96a204859861e85 307 Gene3D G3DSA:3.30.1780.10 15 301 4.1E-99 T 12-10-2018 IPR023401 Ornithine cyclodeaminase, N-terminal Reactome: R-HSA-71064 VAPA_2c08010 780b40982051ef3cf96a204859861e85 307 Pfam PF02423 Ornithine cyclodeaminase/mu-crystallin family 12 304 1.1E-54 T 12-10-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 VAPA_2c08010 780b40982051ef3cf96a204859861e85 307 SUPERFAMILY SSF51735 3 306 2.23E-75 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_2c08010 780b40982051ef3cf96a204859861e85 307 PIRSF PIRSF001439 1 307 3.3E-70 T 12-10-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 VAPA_1c02790 618dca7d63feef0d214f67b7fb9d6142 293 SUPERFAMILY SSF53850 92 293 9.77E-32 T 12-10-2018 VAPA_1c02790 618dca7d63feef0d214f67b7fb9d6142 293 Gene3D G3DSA:3.40.190.10 161 261 6.1E-42 T 12-10-2018 VAPA_1c02790 618dca7d63feef0d214f67b7fb9d6142 293 Gene3D G3DSA:3.40.190.10 101 288 6.1E-42 T 12-10-2018 VAPA_1c02790 618dca7d63feef0d214f67b7fb9d6142 293 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 12 65 9.9E-15 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c02790 618dca7d63feef0d214f67b7fb9d6142 293 Pfam PF03466 LysR substrate binding domain 90 292 1.8E-29 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_1c02790 618dca7d63feef0d214f67b7fb9d6142 293 Gene3D G3DSA:1.10.10.10 8 95 3.3E-16 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c02790 618dca7d63feef0d214f67b7fb9d6142 293 SUPERFAMILY SSF46785 6 81 2.72E-14 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_2c09620 bd3e96ba0d3d10201f8c2f7da86e6099 210 TIGRFAM TIGR00171 leuD: 3-isopropylmalate dehydratase, small subunit 1 188 3.8E-49 T 12-10-2018 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 VAPA_2c09620 bd3e96ba0d3d10201f8c2f7da86e6099 210 SUPERFAMILY SSF52016 1 193 2.75E-45 T 12-10-2018 VAPA_2c09620 bd3e96ba0d3d10201f8c2f7da86e6099 210 Gene3D G3DSA:3.20.19.10 1 176 1.6E-58 T 12-10-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel KEGG: 00290+4.2.1.33 VAPA_2c09620 bd3e96ba0d3d10201f8c2f7da86e6099 210 Pfam PF00694 Aconitase C-terminal domain 51 124 3.1E-24 T 12-10-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain KEGG: 00290+4.2.1.33 VAPA_2c00930 b8a5f3dbd0d77458b018bc8d9c1b2499 302 Gene3D G3DSA:2.40.30.10 19 133 7.4E-24 T 12-10-2018 VAPA_2c00930 b8a5f3dbd0d77458b018bc8d9c1b2499 302 SUPERFAMILY SSF52343 130 295 4.45E-24 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain VAPA_2c00930 b8a5f3dbd0d77458b018bc8d9c1b2499 302 PIRSF PIRSF006816 33 302 1.3E-47 T 12-10-2018 IPR012165 Cytochrome-c3 hydrogenase, gamma subunit GO:0006221|GO:0050660|GO:0051537 VAPA_2c00930 b8a5f3dbd0d77458b018bc8d9c1b2499 302 Gene3D G3DSA:3.40.50.80 141 245 6.9E-13 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain VAPA_2c00930 b8a5f3dbd0d77458b018bc8d9c1b2499 302 Pfam PF10418 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B 255 295 2.9E-14 T 12-10-2018 IPR019480 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain VAPA_2c00930 b8a5f3dbd0d77458b018bc8d9c1b2499 302 SUPERFAMILY SSF63380 37 135 3.58E-18 T 12-10-2018 IPR017938 Riboflavin synthase-like beta-barrel VAPA_2c00930 b8a5f3dbd0d77458b018bc8d9c1b2499 302 Gene3D G3DSA:2.10.240.10 255 296 5.7E-14 T 12-10-2018 IPR037117 Dihydroorotate dehydrogenase, electron transfer subunit, Fe-S binding domain superfamily VAPA_1c39830 940db71a0ffa565a0ad0ecd8bcfe29b6 389 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 131 218 3.2E-13 T 12-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 VAPA_1c39830 940db71a0ffa565a0ad0ecd8bcfe29b6 389 Gene3D G3DSA:1.10.760.10 113 225 1.2E-20 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 VAPA_1c39830 940db71a0ffa565a0ad0ecd8bcfe29b6 389 SUPERFAMILY SSF46626 108 223 5.68E-23 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 VAPA_1c00640 69e8d6d900fabf58fe48bb0e5d86f2e3 92 Pfam PF03776 Septum formation topological specificity factor MinE 14 84 3.9E-24 T 12-10-2018 IPR005527 Cell division topological specificity factor MinE GO:0032955|GO:0051301 VAPA_1c00640 69e8d6d900fabf58fe48bb0e5d86f2e3 92 TIGRFAM TIGR01215 minE: cell division topological specificity factor MinE 1 85 2.9E-28 T 12-10-2018 IPR005527 Cell division topological specificity factor MinE GO:0032955|GO:0051301 VAPA_1c00640 69e8d6d900fabf58fe48bb0e5d86f2e3 92 SUPERFAMILY SSF55229 36 85 1.05E-14 T 12-10-2018 IPR036707 Cell division topological specificity factor MinE superfamily GO:0032955|GO:0051301 VAPA_1c00640 69e8d6d900fabf58fe48bb0e5d86f2e3 92 Gene3D G3DSA:3.30.1070.10 1 85 2.0E-28 T 12-10-2018 IPR036707 Cell division topological specificity factor MinE superfamily GO:0032955|GO:0051301 VAPA_1c00640 69e8d6d900fabf58fe48bb0e5d86f2e3 92 Hamap MF_00262 Cell division topological specificity factor [minE]. 3 86 18.739 T 12-10-2018 IPR005527 Cell division topological specificity factor MinE GO:0032955|GO:0051301 VAPA_1c46850 fefacdba26760be7fab81fc33a8588a2 487 Pfam PF00144 Beta-lactamase 76 356 6.7E-24 T 12-10-2018 IPR001466 Beta-lactamase-related VAPA_1c46850 fefacdba26760be7fab81fc33a8588a2 487 Pfam PF11604 Copper binding periplasmic protein CusF 429 472 6.8E-5 T 12-10-2018 IPR021647 Copper binding periplasmic protein CusF VAPA_1c46850 fefacdba26760be7fab81fc33a8588a2 487 Gene3D G3DSA:3.40.710.10 56 368 1.7E-61 T 12-10-2018 VAPA_1c46850 fefacdba26760be7fab81fc33a8588a2 487 SUPERFAMILY SSF56601 14 366 4.3E-64 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like VAPA_1c45700 a8cacbcd33331eeea60bad45c847c589 153 SUPERFAMILY SSF54637 5 149 2.55E-41 T 12-10-2018 IPR029069 HotDog domain superfamily VAPA_1c45700 a8cacbcd33331eeea60bad45c847c589 153 Gene3D G3DSA:3.10.129.10 3 152 5.2E-52 T 12-10-2018 VAPA_1c45700 a8cacbcd33331eeea60bad45c847c589 153 Pfam PF01575 MaoC like domain 15 116 2.4E-28 T 12-10-2018 IPR002539 MaoC-like dehydratase domain VAPA_1c14840 cf2993486a9355af3b11cae9f2faa340 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 5.6E-48 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c14840 cf2993486a9355af3b11cae9f2faa340 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 5.6E-48 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c14840 cf2993486a9355af3b11cae9f2faa340 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 5.6E-48 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c14840 cf2993486a9355af3b11cae9f2faa340 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 5.6E-48 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c14840 cf2993486a9355af3b11cae9f2faa340 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 5.6E-48 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c14840 cf2993486a9355af3b11cae9f2faa340 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 209 229 5.6E-48 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c14840 cf2993486a9355af3b11cae9f2faa340 247 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 246 2.6E-68 T 12-10-2018 VAPA_1c14840 cf2993486a9355af3b11cae9f2faa340 247 SUPERFAMILY SSF51735 7 247 1.3E-85 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c14840 cf2993486a9355af3b11cae9f2faa340 247 TIGRFAM TIGR01830 3oxo_ACP_reduc: 3-oxoacyl-[acyl-carrier-protein] reductase 11 245 4.2E-101 T 12-10-2018 IPR011284 3-oxoacyl-(acyl-carrier-protein) reductase GO:0004316|GO:0006633|GO:0051287|GO:0055114 KEGG: 00061+1.1.1.100|KEGG: 00780+1.1.1.100|MetaCyc: PWY-5367|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 VAPA_1c14840 cf2993486a9355af3b11cae9f2faa340 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 1.7E-13 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c14840 cf2993486a9355af3b11cae9f2faa340 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 1.7E-13 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c14840 cf2993486a9355af3b11cae9f2faa340 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 1.7E-13 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c14840 cf2993486a9355af3b11cae9f2faa340 247 Gene3D G3DSA:3.40.50.720 1 247 4.9E-86 T 12-10-2018 VAPA_1c14840 cf2993486a9355af3b11cae9f2faa340 247 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 9 190 8.0E-6 T 12-10-2018 VAPA_1c14840 cf2993486a9355af3b11cae9f2faa340 247 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 142 170 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 VAPA_1c46550 09664742f26cd53c0820bfec45d7f611 309 Gene3D G3DSA:3.40.190.290 94 296 3.7E-34 T 12-10-2018 VAPA_1c46550 09664742f26cd53c0820bfec45d7f611 309 Pfam PF03466 LysR substrate binding domain 92 293 4.7E-45 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_1c46550 09664742f26cd53c0820bfec45d7f611 309 SUPERFAMILY SSF53850 94 294 5.31E-41 T 12-10-2018 VAPA_1c46550 09664742f26cd53c0820bfec45d7f611 309 SUPERFAMILY SSF46785 5 89 7.44E-23 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c46550 09664742f26cd53c0820bfec45d7f611 309 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 21 32 2.0E-10 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c46550 09664742f26cd53c0820bfec45d7f611 309 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 32 42 2.0E-10 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c46550 09664742f26cd53c0820bfec45d7f611 309 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 53 2.0E-10 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c46550 09664742f26cd53c0820bfec45d7f611 309 Gene3D G3DSA:1.10.10.10 4 90 6.8E-25 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c46550 09664742f26cd53c0820bfec45d7f611 309 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 64 1.2E-21 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c29120 1d630a157d391c42bb6dede35aea85f1 60 Hamap MF_01187 UPF0434 protein YcaR [ycaR]. 1 54 27.448 T 12-10-2018 IPR038053 Uncharacterised protein family UPF0434 VAPA_1c29120 1d630a157d391c42bb6dede35aea85f1 60 SUPERFAMILY SSF158997 1 56 1.31E-20 T 12-10-2018 VAPA_1c29120 1d630a157d391c42bb6dede35aea85f1 60 Pfam PF03966 Trm112p-like protein 2 41 1.9E-9 T 12-10-2018 IPR005651 Trm112-like VAPA_1c29120 1d630a157d391c42bb6dede35aea85f1 60 Gene3D G3DSA:2.20.25.10 8 60 1.4E-24 T 12-10-2018 VAPA_1c37510 a363de39fd4d46059126814c28b132f7 148 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 45 65 7.5E-5 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 VAPA_1c37510 a363de39fd4d46059126814c28b132f7 148 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 21 34 7.5E-5 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 VAPA_1c37510 a363de39fd4d46059126814c28b132f7 148 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 10 21 7.5E-5 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 VAPA_1c37510 a363de39fd4d46059126814c28b132f7 148 Gene3D G3DSA:1.10.1660.10 7 131 1.3E-29 T 12-10-2018 VAPA_1c37510 a363de39fd4d46059126814c28b132f7 148 SUPERFAMILY SSF46955 9 124 1.54E-28 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily VAPA_1c37510 a363de39fd4d46059126814c28b132f7 148 SMART SM00422 9 78 7.9E-17 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 VAPA_1c37510 a363de39fd4d46059126814c28b132f7 148 Pfam PF13411 MerR HTH family regulatory protein 10 74 1.1E-14 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 VAPA_1c38670 d521f5934b69234fd7a9554f2c791928 1357 SMART SM00823 Phosphopantetheine attachment site 1001 1072 5.0E-5 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 VAPA_1c38670 d521f5934b69234fd7a9554f2c791928 1357 Pfam PF00550 Phosphopantetheine attachment site 1003 1068 4.7E-13 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain VAPA_1c38670 d521f5934b69234fd7a9554f2c791928 1357 SUPERFAMILY SSF56801 492 1014 1.7E-139 T 12-10-2018 VAPA_1c38670 d521f5934b69234fd7a9554f2c791928 1357 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 520 916 1.1E-114 T 12-10-2018 IPR010071 Amino acid adenylation domain VAPA_1c38670 d521f5934b69234fd7a9554f2c791928 1357 Pfam PF00975 Thioesterase domain 1089 1186 1.1E-11 T 12-10-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 VAPA_1c38670 d521f5934b69234fd7a9554f2c791928 1357 Gene3D G3DSA:3.40.50.12780 487 885 2.8E-117 T 12-10-2018 VAPA_1c38670 d521f5934b69234fd7a9554f2c791928 1357 Gene3D G3DSA:3.40.50.1820 1079 1346 2.1E-31 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c38670 d521f5934b69234fd7a9554f2c791928 1357 Gene3D G3DSA:3.30.300.30 886 991 2.1E-31 T 12-10-2018 VAPA_1c38670 d521f5934b69234fd7a9554f2c791928 1357 SUPERFAMILY SSF53474 1078 1334 1.33E-29 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c38670 d521f5934b69234fd7a9554f2c791928 1357 Gene3D G3DSA:3.30.559.10 49 416 5.6E-121 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 VAPA_1c38670 d521f5934b69234fd7a9554f2c791928 1357 Gene3D G3DSA:3.30.559.30 229 471 5.6E-121 T 12-10-2018 VAPA_1c38670 d521f5934b69234fd7a9554f2c791928 1357 SMART SM00824 Thioesterase 1091 1338 8.9E-4 T 12-10-2018 IPR020802 Polyketide synthase, thioesterase domain GO:0009058|GO:0016788 VAPA_1c38670 d521f5934b69234fd7a9554f2c791928 1357 Pfam PF13193 AMP-binding enzyme C-terminal domain 905 975 1.8E-9 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain VAPA_1c38670 d521f5934b69234fd7a9554f2c791928 1357 Gene3D G3DSA:1.10.1200.10 992 1076 1.6E-22 T 12-10-2018 IPR036736 ACP-like superfamily VAPA_1c38670 d521f5934b69234fd7a9554f2c791928 1357 SUPERFAMILY SSF47336 994 1069 1.19E-15 T 12-10-2018 IPR036736 ACP-like superfamily VAPA_1c38670 d521f5934b69234fd7a9554f2c791928 1357 Pfam PF00501 AMP-binding enzyme 499 892 3.8E-82 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 VAPA_1c38670 d521f5934b69234fd7a9554f2c791928 1357 ProSitePatterns PS00455 Putative AMP-binding domain signature. 635 646 - T 12-10-2018 IPR020845 AMP-binding, conserved site VAPA_1c38670 d521f5934b69234fd7a9554f2c791928 1357 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1025 1040 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site VAPA_1c38670 d521f5934b69234fd7a9554f2c791928 1357 SUPERFAMILY SSF52777 51 225 9.12E-35 T 12-10-2018 VAPA_1c38670 d521f5934b69234fd7a9554f2c791928 1357 Pfam PF00668 Condensation domain 48 481 5.4E-79 T 12-10-2018 IPR001242 Condensation domain VAPA_1c38670 d521f5934b69234fd7a9554f2c791928 1357 SUPERFAMILY SSF52777 231 474 1.56E-55 T 12-10-2018 VAPA_1c32850 5c330ec6f8ea8e3053b44800ffdfc075 253 SUPERFAMILY SSF56214 113 197 4.06E-19 T 12-10-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 VAPA_1c32850 5c330ec6f8ea8e3053b44800ffdfc075 253 SUPERFAMILY SSF56214 28 105 7.85E-20 T 12-10-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 VAPA_1c32850 5c330ec6f8ea8e3053b44800ffdfc075 253 Gene3D G3DSA:3.90.470.20 27 134 8.1E-29 T 12-10-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 VAPA_1c32850 5c330ec6f8ea8e3053b44800ffdfc075 253 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 114 186 1.4E-11 T 12-10-2018 IPR008278 4'-phosphopantetheinyl transferase domain GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 VAPA_1c22050 43b1daeeeef07fb3bf5522b27ebbe7eb 330 SUPERFAMILY SSF53756 79 284 1.08E-23 T 12-10-2018 VAPA_1c22050 43b1daeeeef07fb3bf5522b27ebbe7eb 330 Gene3D G3DSA:3.40.50.2000 114 286 1.2E-21 T 12-10-2018 VAPA_1c22050 43b1daeeeef07fb3bf5522b27ebbe7eb 330 TIGRFAM TIGR04348 TIGR04348: putative glycosyltransferase, TIGR04348 family 6 324 9.8E-131 T 12-10-2018 IPR027627 Putative glycosyltransferase VAPA_1c22050 43b1daeeeef07fb3bf5522b27ebbe7eb 330 Pfam PF00534 Glycosyl transferases group 1 137 276 9.2E-15 T 12-10-2018 IPR001296 Glycosyl transferase, family 1 VAPA_2c07200 8e5d5978ada84f13a8f2a8a94a139218 459 SMART SM00304 183 235 4.2E-12 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 VAPA_2c07200 8e5d5978ada84f13a8f2a8a94a139218 459 Gene3D G3DSA:1.10.287.130 188 299 1.1E-25 T 12-10-2018 VAPA_2c07200 8e5d5978ada84f13a8f2a8a94a139218 459 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 346 457 1.5E-23 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase VAPA_2c07200 8e5d5978ada84f13a8f2a8a94a139218 459 SUPERFAMILY SSF55874 289 456 4.71E-42 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_2c07200 8e5d5978ada84f13a8f2a8a94a139218 459 Pfam PF00672 HAMP domain 183 232 2.2E-10 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 VAPA_2c07200 8e5d5978ada84f13a8f2a8a94a139218 459 SUPERFAMILY SSF47384 219 299 2.16E-15 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 VAPA_2c07200 8e5d5978ada84f13a8f2a8a94a139218 459 Gene3D G3DSA:3.30.565.10 305 458 3.6E-40 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_2c07200 8e5d5978ada84f13a8f2a8a94a139218 459 SMART SM00388 236 300 2.7E-14 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 VAPA_2c07200 8e5d5978ada84f13a8f2a8a94a139218 459 Pfam PF00512 His Kinase A (phospho-acceptor) domain 236 297 1.1E-12 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 VAPA_2c07200 8e5d5978ada84f13a8f2a8a94a139218 459 SMART SM00387 346 458 4.0E-38 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase VAPA_2c07200 8e5d5978ada84f13a8f2a8a94a139218 459 PRINTS PR00344 Bacterial sensor protein C-terminal signature 401 411 6.2E-13 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_2c07200 8e5d5978ada84f13a8f2a8a94a139218 459 PRINTS PR00344 Bacterial sensor protein C-terminal signature 442 455 6.2E-13 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_2c07200 8e5d5978ada84f13a8f2a8a94a139218 459 PRINTS PR00344 Bacterial sensor protein C-terminal signature 383 397 6.2E-13 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_2c07200 8e5d5978ada84f13a8f2a8a94a139218 459 PRINTS PR00344 Bacterial sensor protein C-terminal signature 418 436 6.2E-13 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_2c07200 8e5d5978ada84f13a8f2a8a94a139218 459 SUPERFAMILY SSF158472 184 232 3.27E-8 T 12-10-2018 VAPA_1c42730 219c6a5af61774d2235e8dc573a93c22 140 Gene3D G3DSA:3.30.70.100 1 139 7.3E-38 T 12-10-2018 VAPA_1c42730 219c6a5af61774d2235e8dc573a93c22 140 Pfam PF04940 Sensors of blue-light using FAD 2 92 5.4E-29 T 12-10-2018 IPR007024 BLUF domain GO:0009882|GO:0071949 VAPA_1c42730 219c6a5af61774d2235e8dc573a93c22 140 SUPERFAMILY SSF54975 1 133 4.58E-40 T 12-10-2018 IPR036046 Acylphosphatase-like domain superfamily KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 VAPA_1c42730 219c6a5af61774d2235e8dc573a93c22 140 SMART SM01034 2 93 1.2E-45 T 12-10-2018 IPR007024 BLUF domain GO:0009882|GO:0071949 VAPA_1c41890 68a0b211421cdcd8fb774d6e5dc5d9dd 247 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_1c41890 68a0b211421cdcd8fb774d6e5dc5d9dd 247 PIRSF PIRSF039085 1 241 1.5E-106 T 12-10-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 VAPA_1c41890 68a0b211421cdcd8fb774d6e5dc5d9dd 247 SMART SM00382 26 213 6.6E-16 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c41890 68a0b211421cdcd8fb774d6e5dc5d9dd 247 SUPERFAMILY SSF52540 1 235 1.25E-81 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c41890 68a0b211421cdcd8fb774d6e5dc5d9dd 247 Gene3D G3DSA:3.40.50.300 1 241 3.2E-79 T 12-10-2018 VAPA_1c41890 68a0b211421cdcd8fb774d6e5dc5d9dd 247 Pfam PF00005 ABC transporter 19 165 6.3E-36 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c47640 4c78ff7ece35ecedf0a28f2e1ff041fa 177 Pfam PF01584 CheW-like domain 31 166 4.0E-13 T 12-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 VAPA_1c47640 4c78ff7ece35ecedf0a28f2e1ff041fa 177 SUPERFAMILY SSF50341 30 173 3.92E-17 T 12-10-2018 IPR036061 CheW-like domain superfamily GO:0006935|GO:0007165 VAPA_1c47640 4c78ff7ece35ecedf0a28f2e1ff041fa 177 Gene3D G3DSA:2.40.50.180 49 136 2.4E-8 T 12-10-2018 VAPA_1c29770 aad40b2f397f70f2893028b1ed075184 236 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 26 201 6.2E-32 T 12-10-2018 VAPA_1c29770 aad40b2f397f70f2893028b1ed075184 236 TIGRFAM TIGR00338 serB: phosphoserine phosphatase SerB 22 235 1.5E-70 T 12-10-2018 VAPA_1c29770 aad40b2f397f70f2893028b1ed075184 236 Gene3D G3DSA:3.40.50.1000 5 236 5.4E-73 T 12-10-2018 IPR023214 HAD superfamily VAPA_1c29770 aad40b2f397f70f2893028b1ed075184 236 Pfam PF12710 haloacid dehalogenase-like hydrolase 27 200 5.6E-20 T 12-10-2018 VAPA_1c29770 aad40b2f397f70f2893028b1ed075184 236 SUPERFAMILY SSF56784 21 232 1.07E-47 T 12-10-2018 IPR036412 HAD-like superfamily VAPA_1c03480 552c709a9bbf83aa358cc70940cbf582 173 TIGRFAM TIGR03426 shape_MreD: rod shape-determining protein MreD 16 158 2.7E-25 T 12-10-2018 IPR007227 Cell shape-determining protein MreD GO:0008360|GO:0016021 VAPA_1c03480 552c709a9bbf83aa358cc70940cbf582 173 PIRSF PIRSF018472 7 165 1.7E-39 T 12-10-2018 IPR026034 Cell shape-determining protein MreD, proteobacterial type VAPA_1c03480 552c709a9bbf83aa358cc70940cbf582 173 Pfam PF04093 rod shape-determining protein MreD 16 157 7.4E-16 T 12-10-2018 IPR007227 Cell shape-determining protein MreD GO:0008360|GO:0016021 VAPA_1c25940 83c44f03c15b187f46f01ee62e9f2da4 365 Gene3D G3DSA:3.40.50.300 2 285 2.8E-83 T 12-10-2018 VAPA_1c25940 83c44f03c15b187f46f01ee62e9f2da4 365 SUPERFAMILY SSF50331 239 358 5.1E-10 T 12-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal VAPA_1c25940 83c44f03c15b187f46f01ee62e9f2da4 365 SMART SM00382 27 214 5.1E-22 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c25940 83c44f03c15b187f46f01ee62e9f2da4 365 Pfam PF12857 TOBE-like domain 288 352 6.3E-19 T 12-10-2018 IPR024765 TOBE-like domain KEGG: 00920+3.6.3.25 VAPA_1c25940 83c44f03c15b187f46f01ee62e9f2da4 365 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_1c25940 83c44f03c15b187f46f01ee62e9f2da4 365 TIGRFAM TIGR00968 3a0106s01: sulfate ABC transporter, ATP-binding protein 3 241 3.6E-124 T 12-10-2018 IPR005666 Sulphate transport system permease protein 1 GO:0008272|GO:0015419|GO:0016020|GO:0043190 KEGG: 00920+3.6.3.25 VAPA_1c25940 83c44f03c15b187f46f01ee62e9f2da4 365 SUPERFAMILY SSF52540 3 245 3.86E-89 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c25940 83c44f03c15b187f46f01ee62e9f2da4 365 Pfam PF00005 ABC transporter 18 164 9.6E-38 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_2c07810 dea77175ce6dc76a1c704f872a26ebcf 268 Gene3D G3DSA:1.10.10.10 162 268 7.4E-11 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_2c07810 dea77175ce6dc76a1c704f872a26ebcf 268 SUPERFAMILY SSF46894 201 266 3.16E-11 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 VAPA_2c07810 dea77175ce6dc76a1c704f872a26ebcf 268 SMART SM00421 210 267 1.7E-9 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_2c07810 dea77175ce6dc76a1c704f872a26ebcf 268 ProSitePatterns PS00622 LuxR-type HTH domain signature. 227 254 - T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_2c07810 dea77175ce6dc76a1c704f872a26ebcf 268 Pfam PF00196 Bacterial regulatory proteins, luxR family 212 266 9.6E-9 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_1c11870 42da770e246b7cc66684ffb92074e463 298 PIRSF PIRSF026649 1 290 1.4E-61 T 12-10-2018 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 VAPA_1c11870 42da770e246b7cc66684ffb92074e463 298 Pfam PF03279 Bacterial lipid A biosynthesis acyltransferase 2 281 2.7E-30 T 12-10-2018 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 VAPA_1c46800 a83145ec364da6a22e04f87014455d85 1275 SMART SM00567 E-Z type HEAT repeats 312 341 200.0 T 12-10-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 VAPA_1c46800 a83145ec364da6a22e04f87014455d85 1275 SMART SM00567 E-Z type HEAT repeats 281 310 640.0 T 12-10-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 VAPA_1c46800 a83145ec364da6a22e04f87014455d85 1275 SMART SM00567 E-Z type HEAT repeats 648 677 0.0012 T 12-10-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 VAPA_1c46800 a83145ec364da6a22e04f87014455d85 1275 Gene3D G3DSA:1.25.10.10 593 715 3.3E-6 T 12-10-2018 IPR011989 Armadillo-like helical VAPA_1c46800 a83145ec364da6a22e04f87014455d85 1275 Pfam PF13569 Domain of unknown function (DUF4132) 989 1176 5.2E-34 T 12-10-2018 IPR025406 Domain of unknown function DUF4132 VAPA_1c46800 a83145ec364da6a22e04f87014455d85 1275 SUPERFAMILY SSF48371 267 356 9.6E-6 T 12-10-2018 IPR016024 Armadillo-type fold VAPA_1c46800 a83145ec364da6a22e04f87014455d85 1275 SUPERFAMILY SSF48371 640 737 6.08E-6 T 12-10-2018 IPR016024 Armadillo-type fold VAPA_2c03570 f04f5f78d42483fbf9b60287e1fec606 482 Gene3D G3DSA:3.40.50.12780 3 366 1.8E-69 T 12-10-2018 VAPA_2c03570 f04f5f78d42483fbf9b60287e1fec606 482 SUPERFAMILY SSF56801 8 474 1.83E-83 T 12-10-2018 VAPA_2c03570 f04f5f78d42483fbf9b60287e1fec606 482 Gene3D G3DSA:3.30.300.30 371 477 9.4E-7 T 12-10-2018 VAPA_2c03570 f04f5f78d42483fbf9b60287e1fec606 482 Pfam PF00501 AMP-binding enzyme 10 373 1.3E-54 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 VAPA_2c03570 f04f5f78d42483fbf9b60287e1fec606 482 ProSitePatterns PS00455 Putative AMP-binding domain signature. 135 146 - T 12-10-2018 IPR020845 AMP-binding, conserved site VAPA_2c08790 fd27112808d0b210e41e00827c559fef 956 Gene3D G3DSA:1.10.10.10 23 133 4.6E-19 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_2c08790 fd27112808d0b210e41e00827c559fef 956 Gene3D G3DSA:1.25.40.10 849 955 1.7E-8 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 VAPA_2c08790 fd27112808d0b210e41e00827c559fef 956 Gene3D G3DSA:1.25.40.10 564 832 1.6E-8 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 VAPA_2c08790 fd27112808d0b210e41e00827c559fef 956 PRINTS PR00364 Disease resistance protein signature 246 260 2.6E-7 T 12-10-2018 VAPA_2c08790 fd27112808d0b210e41e00827c559fef 956 PRINTS PR00364 Disease resistance protein signature 178 193 2.6E-7 T 12-10-2018 VAPA_2c08790 fd27112808d0b210e41e00827c559fef 956 PRINTS PR00364 Disease resistance protein signature 352 366 2.6E-7 T 12-10-2018 VAPA_2c08790 fd27112808d0b210e41e00827c559fef 956 Pfam PF00486 Transcriptional regulatory protein, C terminal 44 122 1.2E-14 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 VAPA_2c08790 fd27112808d0b210e41e00827c559fef 956 SUPERFAMILY SSF46894 26 123 3.4E-15 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 VAPA_2c08790 fd27112808d0b210e41e00827c559fef 956 SUPERFAMILY SSF48452 861 949 6.64E-7 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 VAPA_2c08790 fd27112808d0b210e41e00827c559fef 956 SMART SM00862 44 122 2.4E-15 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 VAPA_2c08790 fd27112808d0b210e41e00827c559fef 956 Gene3D G3DSA:3.40.50.300 143 296 1.1E-17 T 12-10-2018 VAPA_2c08790 fd27112808d0b210e41e00827c559fef 956 SUPERFAMILY SSF52540 152 419 4.36E-18 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_2c08790 fd27112808d0b210e41e00827c559fef 956 Pfam PF13401 AAA domain 175 269 3.6E-7 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c31030 909bd083aebb63caf0db8dc9f376e4c0 390 Gene3D G3DSA:3.40.50.2300 263 355 3.0E-5 T 12-10-2018 VAPA_1c31030 909bd083aebb63caf0db8dc9f376e4c0 390 Gene3D G3DSA:3.40.50.2300 267 349 3.0E-5 T 12-10-2018 VAPA_1c31030 909bd083aebb63caf0db8dc9f376e4c0 390 Gene3D G3DSA:3.40.50.2300 58 153 8.6E-6 T 12-10-2018 VAPA_1c31030 909bd083aebb63caf0db8dc9f376e4c0 390 SUPERFAMILY SSF53822 87 353 2.69E-18 T 12-10-2018 IPR028082 Periplasmic binding protein-like I VAPA_1c31030 909bd083aebb63caf0db8dc9f376e4c0 390 Gene3D G3DSA:3.40.50.2300 154 210 8.6E-6 T 12-10-2018 VAPA_1c35970 32a09ec8371a794e12e4212a32ea76b0 520 Gene3D G3DSA:1.20.1720.10 23 260 7.3E-46 T 12-10-2018 VAPA_1c35970 32a09ec8371a794e12e4212a32ea76b0 520 Pfam PF07690 Major Facilitator Superfamily 27 419 9.3E-55 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 VAPA_1c35970 32a09ec8371a794e12e4212a32ea76b0 520 SUPERFAMILY SSF103473 14 507 3.66E-68 T 12-10-2018 IPR036259 MFS transporter superfamily VAPA_1c35970 32a09ec8371a794e12e4212a32ea76b0 520 Gene3D G3DSA:1.20.1250.20 269 508 2.8E-14 T 12-10-2018 VAPA_1c35970 32a09ec8371a794e12e4212a32ea76b0 520 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 23 502 2.0E-161 T 12-10-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0016021|GO:0022857|GO:0055085 VAPA_1c42770 8298db183ee986ea103ef61326369bee 601 Pfam PF02938 GAD domain 310 411 3.0E-26 T 12-10-2018 IPR029351 GAD domain Reactome: R-HSA-379726 VAPA_1c42770 8298db183ee986ea103ef61326369bee 601 Gene3D G3DSA:3.30.930.10 120 593 2.0E-193 T 12-10-2018 VAPA_1c42770 8298db183ee986ea103ef61326369bee 601 Pfam PF01336 OB-fold nucleic acid binding domain 20 104 3.8E-18 T 12-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 VAPA_1c42770 8298db183ee986ea103ef61326369bee 601 TIGRFAM TIGR00459 aspS_bact: aspartate--tRNA ligase 3 593 5.3E-241 T 12-10-2018 IPR004524 Aspartate-tRNA ligase, type 1 GO:0005524|GO:0016874 Reactome: R-HSA-379726 VAPA_1c42770 8298db183ee986ea103ef61326369bee 601 Gene3D G3DSA:2.40.50.140 1 107 1.3E-35 T 12-10-2018 VAPA_1c42770 8298db183ee986ea103ef61326369bee 601 Pfam PF00152 tRNA synthetases class II (D, K and N) 121 569 1.2E-106 T 12-10-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 VAPA_1c42770 8298db183ee986ea103ef61326369bee 601 PRINTS PR01042 Aspartyl-tRNA synthetase signature 210 223 5.4E-26 T 12-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 VAPA_1c42770 8298db183ee986ea103ef61326369bee 601 PRINTS PR01042 Aspartyl-tRNA synthetase signature 193 205 5.4E-26 T 12-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 VAPA_1c42770 8298db183ee986ea103ef61326369bee 601 PRINTS PR01042 Aspartyl-tRNA synthetase signature 529 543 5.4E-26 T 12-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 VAPA_1c42770 8298db183ee986ea103ef61326369bee 601 PRINTS PR01042 Aspartyl-tRNA synthetase signature 485 501 5.4E-26 T 12-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 VAPA_1c42770 8298db183ee986ea103ef61326369bee 601 Hamap MF_00044 Aspartate--tRNA(Asp/Asn) ligase [aspS]. 3 595 33.845 T 12-10-2018 IPR004524 Aspartate-tRNA ligase, type 1 GO:0005524|GO:0016874 Reactome: R-HSA-379726 VAPA_1c42770 8298db183ee986ea103ef61326369bee 601 SUPERFAMILY SSF55261 293 421 4.74E-40 T 12-10-2018 IPR004115 GAD-like domain superfamily GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 VAPA_1c42770 8298db183ee986ea103ef61326369bee 601 Gene3D G3DSA:3.30.1360.30 274 431 2.0E-193 T 12-10-2018 IPR004115 GAD-like domain superfamily GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 VAPA_1c42770 8298db183ee986ea103ef61326369bee 601 SUPERFAMILY SSF50249 3 107 5.71E-34 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold VAPA_1c42770 8298db183ee986ea103ef61326369bee 601 SUPERFAMILY SSF55681 113 595 6.77E-103 T 12-10-2018 VAPA_1c30670 07ff6ca33fba4ebcdf2f99b21732162f 514 SUPERFAMILY SSF46689 462 508 1.22E-9 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 VAPA_1c30670 07ff6ca33fba4ebcdf2f99b21732162f 514 Pfam PF00158 Sigma-54 interaction domain 191 357 3.4E-62 T 12-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 VAPA_1c30670 07ff6ca33fba4ebcdf2f99b21732162f 514 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 214 227 - T 12-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 VAPA_1c30670 07ff6ca33fba4ebcdf2f99b21732162f 514 SUPERFAMILY SSF55785 31 114 5.93E-8 T 12-10-2018 IPR035965 PAS domain superfamily VAPA_1c30670 07ff6ca33fba4ebcdf2f99b21732162f 514 SMART SM00382 210 355 2.7E-8 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c30670 07ff6ca33fba4ebcdf2f99b21732162f 514 Gene3D G3DSA:1.10.10.60 443 511 2.7E-13 T 12-10-2018 VAPA_1c30670 07ff6ca33fba4ebcdf2f99b21732162f 514 Gene3D G3DSA:1.10.8.60 362 440 2.6E-18 T 12-10-2018 VAPA_1c30670 07ff6ca33fba4ebcdf2f99b21732162f 514 Gene3D G3DSA:3.40.50.300 175 361 6.3E-62 T 12-10-2018 VAPA_1c30670 07ff6ca33fba4ebcdf2f99b21732162f 514 Pfam PF02954 Bacterial regulatory protein, Fis family 470 507 1.2E-11 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 VAPA_1c30670 07ff6ca33fba4ebcdf2f99b21732162f 514 Pfam PF13188 PAS domain 31 83 3.6E-4 T 12-10-2018 IPR000014 PAS domain VAPA_1c30670 07ff6ca33fba4ebcdf2f99b21732162f 514 SUPERFAMILY SSF52540 190 434 3.03E-64 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c30670 07ff6ca33fba4ebcdf2f99b21732162f 514 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 277 292 - T 12-10-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 VAPA_1c30670 07ff6ca33fba4ebcdf2f99b21732162f 514 Gene3D G3DSA:3.30.450.20 21 136 7.1E-9 T 12-10-2018 VAPA_1c31250 c2ce8b17f4aa2b7a407b48ce2072537a 215 Pfam PF00196 Bacterial regulatory proteins, luxR family 152 206 2.0E-14 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_1c31250 c2ce8b17f4aa2b7a407b48ce2072537a 215 SUPERFAMILY SSF52172 7 136 1.08E-32 T 12-10-2018 IPR011006 CheY-like superfamily VAPA_1c31250 c2ce8b17f4aa2b7a407b48ce2072537a 215 ProSitePatterns PS00622 LuxR-type HTH domain signature. 167 194 - T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_1c31250 c2ce8b17f4aa2b7a407b48ce2072537a 215 SUPERFAMILY SSF46894 144 213 2.75E-19 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 VAPA_1c31250 c2ce8b17f4aa2b7a407b48ce2072537a 215 Gene3D G3DSA:3.40.50.12740 8 213 3.0E-58 T 12-10-2018 VAPA_1c31250 c2ce8b17f4aa2b7a407b48ce2072537a 215 SMART SM00421 150 207 9.3E-15 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_1c31250 c2ce8b17f4aa2b7a407b48ce2072537a 215 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 153 167 1.0E-8 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_1c31250 c2ce8b17f4aa2b7a407b48ce2072537a 215 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 183 195 1.0E-8 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_1c31250 c2ce8b17f4aa2b7a407b48ce2072537a 215 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 167 183 1.0E-8 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_1c31250 c2ce8b17f4aa2b7a407b48ce2072537a 215 Pfam PF00072 Response regulator receiver domain 10 121 1.2E-27 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_1c31250 c2ce8b17f4aa2b7a407b48ce2072537a 215 SMART SM00448 8 120 1.7E-30 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_1c44020 89a1b5330648871b6819dc8bcdaec7a2 582 Gene3D G3DSA:2.30.40.10 4 495 2.2E-287 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 VAPA_1c44020 89a1b5330648871b6819dc8bcdaec7a2 582 Pfam PF00449 Urease alpha-subunit, N-terminal domain 3 124 2.2E-54 T 12-10-2018 IPR011612 Urease alpha-subunit, N-terminal domain KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 VAPA_1c44020 89a1b5330648871b6819dc8bcdaec7a2 582 ProSitePatterns PS00145 Urease active site. 322 338 - T 12-10-2018 IPR017950 Urease active site GO:0009039 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 VAPA_1c44020 89a1b5330648871b6819dc8bcdaec7a2 582 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 442 455 2.5E-34 T 12-10-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 VAPA_1c44020 89a1b5330648871b6819dc8bcdaec7a2 582 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 339 355 2.5E-34 T 12-10-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 VAPA_1c44020 89a1b5330648871b6819dc8bcdaec7a2 582 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 300 317 2.5E-34 T 12-10-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 VAPA_1c44020 89a1b5330648871b6819dc8bcdaec7a2 582 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 416 431 2.5E-34 T 12-10-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 VAPA_1c44020 89a1b5330648871b6819dc8bcdaec7a2 582 Gene3D G3DSA:3.20.20.140 134 582 2.2E-287 T 12-10-2018 VAPA_1c44020 89a1b5330648871b6819dc8bcdaec7a2 582 SUPERFAMILY SSF51338 2 182 5.14E-58 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 VAPA_1c44020 89a1b5330648871b6819dc8bcdaec7a2 582 TIGRFAM TIGR01792 urease_alph: urease, alpha subunit 4 582 5.8E-282 T 12-10-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 VAPA_1c44020 89a1b5330648871b6819dc8bcdaec7a2 582 Hamap MF_01953 Urease subunit alpha [ureC]. 2 582 55.571 T 12-10-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 VAPA_1c44020 89a1b5330648871b6819dc8bcdaec7a2 582 SUPERFAMILY SSF51556 135 582 3.12E-190 T 12-10-2018 IPR032466 Metal-dependent hydrolase VAPA_1c44020 89a1b5330648871b6819dc8bcdaec7a2 582 SUPERFAMILY SSF51338 437 492 3.38E-6 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 VAPA_1c44020 89a1b5330648871b6819dc8bcdaec7a2 582 Pfam PF01979 Amidohydrolase family 130 459 2.0E-75 T 12-10-2018 IPR006680 Amidohydrolase-related GO:0016787 VAPA_1c44020 89a1b5330648871b6819dc8bcdaec7a2 582 ProSitePatterns PS01120 Urease nickel ligands signature. 132 145 - T 12-10-2018 IPR029754 Urease nickel binding site GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 VAPA_1c17410 d44c4e351d8321cd1b2dbfb032c38bdc 509 SUPERFAMILY SSF52172 2 187 2.28E-36 T 12-10-2018 IPR011006 CheY-like superfamily VAPA_1c17410 d44c4e351d8321cd1b2dbfb032c38bdc 509 Gene3D G3DSA:3.40.50.2300 1 127 1.0E-31 T 12-10-2018 VAPA_1c17410 d44c4e351d8321cd1b2dbfb032c38bdc 509 Pfam PF00158 Sigma-54 interaction domain 143 308 7.5E-69 T 12-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 VAPA_1c17410 d44c4e351d8321cd1b2dbfb032c38bdc 509 Pfam PF02954 Bacterial regulatory protein, Fis family 468 506 3.4E-10 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 VAPA_1c17410 d44c4e351d8321cd1b2dbfb032c38bdc 509 Gene3D G3DSA:1.10.10.60 426 509 6.9E-18 T 12-10-2018 VAPA_1c17410 d44c4e351d8321cd1b2dbfb032c38bdc 509 SMART SM00382 162 318 1.0E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c17410 d44c4e351d8321cd1b2dbfb032c38bdc 509 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 228 243 - T 12-10-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 VAPA_1c17410 d44c4e351d8321cd1b2dbfb032c38bdc 509 Pfam PF00072 Response regulator receiver domain 4 119 5.7E-23 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_1c17410 d44c4e351d8321cd1b2dbfb032c38bdc 509 TIGRFAM TIGR01818 ntrC: nitrogen regulation protein NR(I) 4 398 9.8E-188 T 12-10-2018 IPR010114 DNA-binding transcriptional regulator NtrC GO:0000156|GO:0000160|GO:0003677|GO:0005524|GO:0006808 VAPA_1c17410 d44c4e351d8321cd1b2dbfb032c38bdc 509 Gene3D G3DSA:1.10.8.60 313 392 1.7E-19 T 12-10-2018 VAPA_1c17410 d44c4e351d8321cd1b2dbfb032c38bdc 509 SUPERFAMILY SSF46689 434 509 2.02E-16 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 VAPA_1c17410 d44c4e351d8321cd1b2dbfb032c38bdc 509 SUPERFAMILY SSF52540 142 385 2.81E-73 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c17410 d44c4e351d8321cd1b2dbfb032c38bdc 509 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 489 509 1.7E-9 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 VAPA_1c17410 d44c4e351d8321cd1b2dbfb032c38bdc 509 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 472 489 1.7E-9 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 VAPA_1c17410 d44c4e351d8321cd1b2dbfb032c38bdc 509 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 355 364 - T 12-10-2018 IPR025944 Sigma-54 interaction domain, conserved site VAPA_1c17410 d44c4e351d8321cd1b2dbfb032c38bdc 509 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 166 179 - T 12-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 VAPA_1c17410 d44c4e351d8321cd1b2dbfb032c38bdc 509 SMART SM00448 2 119 6.3E-27 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_1c17410 d44c4e351d8321cd1b2dbfb032c38bdc 509 Gene3D G3DSA:3.40.50.300 128 312 7.0E-64 T 12-10-2018 VAPA_1c31260 dd1e440b8395f00cbe9c8b1ddc69f3a2 218 SUPERFAMILY SSF56784 1 203 1.47E-26 T 12-10-2018 IPR036412 HAD-like superfamily VAPA_1c31260 dd1e440b8395f00cbe9c8b1ddc69f3a2 218 TIGRFAM TIGR01490 HAD-SF-IB-hyp1: HAD hydrolase, family IB 3 202 1.1E-34 T 12-10-2018 IPR006385 HAD-superfamily hydrolase, subfamily IB, SerB1-like VAPA_1c31260 dd1e440b8395f00cbe9c8b1ddc69f3a2 218 Gene3D G3DSA:1.20.1440.100 15 86 1.1E-64 T 12-10-2018 VAPA_1c31260 dd1e440b8395f00cbe9c8b1ddc69f3a2 218 Pfam PF12710 haloacid dehalogenase-like hydrolase 4 188 8.5E-34 T 12-10-2018 VAPA_1c31260 dd1e440b8395f00cbe9c8b1ddc69f3a2 218 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 3 188 1.3E-18 T 12-10-2018 VAPA_1c31260 dd1e440b8395f00cbe9c8b1ddc69f3a2 218 Gene3D G3DSA:3.40.50.1000 3 215 1.1E-64 T 12-10-2018 IPR023214 HAD superfamily VAPA_1c35530 9631e35a109700518342337bdb842b7f 427 Gene3D G3DSA:3.20.20.120 129 427 9.1E-131 T 12-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily VAPA_1c35530 9631e35a109700518342337bdb842b7f 427 ProSitePatterns PS00164 Enolase signature. 334 347 - T 12-10-2018 IPR020809 Enolase, conserved site KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: R-HSA-70171|Reactome: R-HSA-70263 VAPA_1c35530 9631e35a109700518342337bdb842b7f 427 Gene3D G3DSA:3.30.390.10 1 127 2.4E-55 T 12-10-2018 IPR029017 Enolase-like, N-terminal VAPA_1c35530 9631e35a109700518342337bdb842b7f 427 TIGRFAM TIGR01060 eno: phosphopyruvate hydratase 4 425 4.3E-207 T 12-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 VAPA_1c35530 9631e35a109700518342337bdb842b7f 427 SMART SM01193 4 134 9.7E-96 T 12-10-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 VAPA_1c35530 9631e35a109700518342337bdb842b7f 427 PIRSF PIRSF001400 1 425 2.5E-187 T 12-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 VAPA_1c35530 9631e35a109700518342337bdb842b7f 427 Hamap MF_00318 Enolase [eno]. 2 411 45.061 T 12-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 VAPA_1c35530 9631e35a109700518342337bdb842b7f 427 SUPERFAMILY SSF51604 140 426 3.68E-128 T 12-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily VAPA_1c35530 9631e35a109700518342337bdb842b7f 427 Pfam PF03952 Enolase, N-terminal domain 4 133 7.8E-59 T 12-10-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 VAPA_1c35530 9631e35a109700518342337bdb842b7f 427 SMART SM01192 139 425 9.3E-220 T 12-10-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 VAPA_1c35530 9631e35a109700518342337bdb842b7f 427 PRINTS PR00148 Enolase signature 107 123 4.7E-45 T 12-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 VAPA_1c35530 9631e35a109700518342337bdb842b7f 427 PRINTS PR00148 Enolase signature 363 380 4.7E-45 T 12-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 VAPA_1c35530 9631e35a109700518342337bdb842b7f 427 PRINTS PR00148 Enolase signature 311 322 4.7E-45 T 12-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 VAPA_1c35530 9631e35a109700518342337bdb842b7f 427 PRINTS PR00148 Enolase signature 161 174 4.7E-45 T 12-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 VAPA_1c35530 9631e35a109700518342337bdb842b7f 427 PRINTS PR00148 Enolase signature 37 51 4.7E-45 T 12-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 VAPA_1c35530 9631e35a109700518342337bdb842b7f 427 PRINTS PR00148 Enolase signature 334 348 4.7E-45 T 12-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 VAPA_1c35530 9631e35a109700518342337bdb842b7f 427 SUPERFAMILY SSF54826 4 137 4.6E-56 T 12-10-2018 VAPA_1c35530 9631e35a109700518342337bdb842b7f 427 Pfam PF00113 Enolase, C-terminal TIM barrel domain 141 423 2.2E-129 T 12-10-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 VAPA_1c36090 0971cac69431e1a3296d614970274f96 219 Pfam PF00499 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 19 165 1.3E-34 T 12-10-2018 IPR001457 NADH:ubiquinone/plastoquinone oxidoreductase, chain 6 GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VAPA_1c36090 0971cac69431e1a3296d614970274f96 219 Gene3D G3DSA:1.20.120.1200 5 167 1.9E-41 T 12-10-2018 VAPA_1c41640 e3785490a89ab87d735ff068562d1324 308 Pfam PF12852 Cupin 2 183 1.2E-42 T 12-10-2018 IPR032783 AraC-type transcription regulator, ligand-binding domain VAPA_1c41640 e3785490a89ab87d735ff068562d1324 308 Gene3D G3DSA:1.10.10.60 196 304 1.3E-25 T 12-10-2018 VAPA_1c41640 e3785490a89ab87d735ff068562d1324 308 Pfam PF12833 Helix-turn-helix domain 222 300 1.4E-17 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 VAPA_1c41640 e3785490a89ab87d735ff068562d1324 308 SUPERFAMILY SSF46689 199 250 5.02E-7 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 VAPA_1c41640 e3785490a89ab87d735ff068562d1324 308 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 268 283 4.3E-5 T 12-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 VAPA_1c41640 e3785490a89ab87d735ff068562d1324 308 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 283 299 4.3E-5 T 12-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 VAPA_1c41640 e3785490a89ab87d735ff068562d1324 308 SUPERFAMILY SSF46689 252 301 3.18E-10 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 VAPA_1c41640 e3785490a89ab87d735ff068562d1324 308 SMART SM00342 216 299 8.3E-24 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 VAPA_1c11170 cd5f7ac5684cb095fd6475d843cbb12f 593 SUPERFAMILY SSF52540 376 565 1.61E-35 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c11170 cd5f7ac5684cb095fd6475d843cbb12f 593 SUPERFAMILY SSF90123 33 353 9.42E-22 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 VAPA_1c11170 cd5f7ac5684cb095fd6475d843cbb12f 593 Pfam PF06472 ABC transporter transmembrane region 2 13 310 2.4E-65 T 12-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 VAPA_1c11170 cd5f7ac5684cb095fd6475d843cbb12f 593 Pfam PF00005 ABC transporter 398 527 2.4E-16 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c11170 cd5f7ac5684cb095fd6475d843cbb12f 593 Gene3D G3DSA:1.20.1560.10 17 359 5.2E-6 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 VAPA_1c11170 cd5f7ac5684cb095fd6475d843cbb12f 593 ProSitePatterns PS00211 ABC transporters family signature. 500 514 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_1c11170 cd5f7ac5684cb095fd6475d843cbb12f 593 Gene3D G3DSA:3.40.50.300 380 571 4.5E-38 T 12-10-2018 VAPA_1c11170 cd5f7ac5684cb095fd6475d843cbb12f 593 SMART SM00382 404 576 1.0E-7 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c20110 45fa9a861bd45183e456fb5be640b546 350 Pfam PF03773 Predicted permease 55 347 5.9E-74 T 12-10-2018 IPR005524 Predicted permease DUF318 VAPA_1c46390 36506fbe1d2ce9c2f6cb3b7ea6d961fe 320 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 53 2.6E-7 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c46390 36506fbe1d2ce9c2f6cb3b7ea6d961fe 320 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 21 32 2.6E-7 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c46390 36506fbe1d2ce9c2f6cb3b7ea6d961fe 320 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 32 42 2.6E-7 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c46390 36506fbe1d2ce9c2f6cb3b7ea6d961fe 320 Gene3D G3DSA:3.40.190.10 173 277 5.0E-43 T 12-10-2018 VAPA_1c46390 36506fbe1d2ce9c2f6cb3b7ea6d961fe 320 SUPERFAMILY SSF46785 5 118 8.27E-19 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c46390 36506fbe1d2ce9c2f6cb3b7ea6d961fe 320 SUPERFAMILY SSF53850 98 308 4.56E-34 T 12-10-2018 VAPA_1c46390 36506fbe1d2ce9c2f6cb3b7ea6d961fe 320 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 68 7.6E-17 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c46390 36506fbe1d2ce9c2f6cb3b7ea6d961fe 320 Gene3D G3DSA:3.40.190.10 99 292 5.0E-43 T 12-10-2018 VAPA_1c46390 36506fbe1d2ce9c2f6cb3b7ea6d961fe 320 Pfam PF03466 LysR substrate binding domain 94 304 1.6E-32 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_1c46390 36506fbe1d2ce9c2f6cb3b7ea6d961fe 320 Gene3D G3DSA:1.10.10.10 1 90 9.3E-22 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_2c01200 1367b74c51562e10a97ad67a16140f06 250 SUPERFAMILY SSF56281 37 242 2.65E-10 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like VAPA_2c01200 1367b74c51562e10a97ad67a16140f06 250 Pfam PF14234 Domain of unknown function (DUF4336) 40 171 1.9E-13 T 12-10-2018 IPR025638 Protein of unknown function DUF4336 VAPA_1c53080 dac8fbfaf4507504547d878c9607e185 797 Pfam PF07793 Protein of unknown function (DUF1631) 6 788 3.7E-138 T 12-10-2018 IPR012434 Protein of unknown function DUF1631 VAPA_2c10810 ba2af8cc6932b6a20d0b2d6a611d9420 201 SUPERFAMILY SSF47616 73 197 2.94E-13 T 12-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily VAPA_2c10810 ba2af8cc6932b6a20d0b2d6a611d9420 201 Pfam PF13417 Glutathione S-transferase, N-terminal domain 3 80 1.0E-13 T 12-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 VAPA_2c10810 ba2af8cc6932b6a20d0b2d6a611d9420 201 SUPERFAMILY SSF52833 1 86 3.34E-15 T 12-10-2018 IPR036249 Thioredoxin-like superfamily VAPA_2c10810 ba2af8cc6932b6a20d0b2d6a611d9420 201 Gene3D G3DSA:3.40.30.10 3 192 1.7E-59 T 12-10-2018 VAPA_2c10810 ba2af8cc6932b6a20d0b2d6a611d9420 201 Gene3D G3DSA:1.20.1050.10 82 190 1.7E-59 T 12-10-2018 VAPA_1c22840 6181c2c0952315b5e8bfecb24a44b2b5 68 Pfam PF01361 Tautomerase enzyme 2 57 2.6E-18 T 12-10-2018 IPR004370 4-oxalocrotonate tautomerase GO:0006725|GO:0016853 VAPA_1c22840 6181c2c0952315b5e8bfecb24a44b2b5 68 SUPERFAMILY SSF55331 2 61 2.62E-17 T 12-10-2018 IPR014347 Tautomerase/MIF superfamily VAPA_1c22840 6181c2c0952315b5e8bfecb24a44b2b5 68 TIGRFAM TIGR00013 taut: 4-oxalocrotonate tautomerase family enzyme 1 55 4.3E-18 T 12-10-2018 IPR018191 4-oxalocrotonate tautomerase, Pseudomonas-type GO:0006725|GO:0016853 VAPA_1c22840 6181c2c0952315b5e8bfecb24a44b2b5 68 Gene3D G3DSA:3.30.429.10 1 67 6.5E-24 T 12-10-2018 IPR014347 Tautomerase/MIF superfamily VAPA_2c05740 40ac48d00bb1eaf49bd873ea2cd72370 128 Pfam PF01124 MAPEG family 8 123 3.6E-20 T 12-10-2018 IPR001129 Membrane-associated, eicosanoid/glutathione metabolism (MAPEG) protein VAPA_2c05740 40ac48d00bb1eaf49bd873ea2cd72370 128 Gene3D G3DSA:1.20.120.550 4 127 1.9E-18 T 12-10-2018 IPR023352 Membrane associated eicosanoid/glutathione metabolism-like domain superfamily VAPA_2c05740 40ac48d00bb1eaf49bd873ea2cd72370 128 SUPERFAMILY SSF161084 2 124 1.57E-21 T 12-10-2018 IPR023352 Membrane associated eicosanoid/glutathione metabolism-like domain superfamily VAPA_1c05850 0ceebfabb877c289ab3747635e6766c6 1851 SUPERFAMILY SSF51126 64 370 4.08E-29 T 12-10-2018 IPR011050 Pectin lyase fold/virulence factor VAPA_1c05850 0ceebfabb877c289ab3747635e6766c6 1851 TIGRFAM TIGR01901 adhes_NPXG: filamentous hemagglutinin family N-terminal domain 75 155 2.5E-16 T 12-10-2018 IPR008638 Filamentous haemagglutinin, N-terminal VAPA_1c05850 0ceebfabb877c289ab3747635e6766c6 1851 Pfam PF05860 haemagglutination activity domain 57 157 9.7E-16 T 12-10-2018 IPR008638 Filamentous haemagglutinin, N-terminal VAPA_1c05850 0ceebfabb877c289ab3747635e6766c6 1851 Gene3D G3DSA:2.160.20.10 42 436 7.8E-58 T 12-10-2018 IPR012334 Pectin lyase fold VAPA_1c05850 0ceebfabb877c289ab3747635e6766c6 1851 Gene3D G3DSA:2.160.20.10 738 923 6.6E-11 T 12-10-2018 IPR012334 Pectin lyase fold VAPA_1c05850 0ceebfabb877c289ab3747635e6766c6 1851 SMART SM00912 39 158 1.7E-25 T 12-10-2018 IPR008638 Filamentous haemagglutinin, N-terminal VAPA_1c12170 2964dd7de2a7e9c267cb1389b96e600b 222 Pfam PF05494 MlaC protein 45 209 9.5E-55 T 12-10-2018 IPR008869 Toluene tolerance Ttg2/phospholipid-binding protein MlaC VAPA_1c12170 2964dd7de2a7e9c267cb1389b96e600b 222 Gene3D G3DSA:3.10.450.50 46 183 9.0E-58 T 12-10-2018 VAPA_1c12170 2964dd7de2a7e9c267cb1389b96e600b 222 PIRSF PIRSF004649 11 222 3.3E-47 T 12-10-2018 IPR008869 Toluene tolerance Ttg2/phospholipid-binding protein MlaC VAPA_1c12170 2964dd7de2a7e9c267cb1389b96e600b 222 Gene3D G3DSA:1.10.10.640 82 208 9.0E-58 T 12-10-2018 VAPA_1c08260 abe49574f05fb0eb5f911db616fa7de0 249 Pfam PF00005 ABC transporter 48 180 4.4E-16 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c08260 abe49574f05fb0eb5f911db616fa7de0 249 SUPERFAMILY SSF52540 45 233 1.64E-37 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c08260 abe49574f05fb0eb5f911db616fa7de0 249 SMART SM00382 57 227 1.7E-7 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c08260 abe49574f05fb0eb5f911db616fa7de0 249 Gene3D G3DSA:3.40.50.300 35 248 4.9E-37 T 12-10-2018 VAPA_1c17340 eb32ae9b56e6bbfde532cab7f0f0872d 269 SUPERFAMILY SSF88713 27 259 1.58E-39 T 12-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 VAPA_1c17340 eb32ae9b56e6bbfde532cab7f0f0872d 269 Pfam PF01522 Polysaccharide deacetylase 31 182 4.1E-19 T 12-10-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 VAPA_1c17340 eb32ae9b56e6bbfde532cab7f0f0872d 269 Gene3D G3DSA:3.20.20.370 27 261 2.3E-35 T 12-10-2018 VAPA_1c20470 d81c4c882103b3793214aefc5341304f 445 Pfam PF03972 MmgE/PrpD family 4 432 1.8E-113 T 12-10-2018 IPR005656 MmgE/PrpD GO:0016829 VAPA_1c20470 d81c4c882103b3793214aefc5341304f 445 Gene3D G3DSA:1.10.4100.10 23 413 1.9E-102 T 12-10-2018 VAPA_1c20470 d81c4c882103b3793214aefc5341304f 445 Gene3D G3DSA:3.30.1330.120 265 396 1.9E-102 T 12-10-2018 VAPA_1c20470 d81c4c882103b3793214aefc5341304f 445 SUPERFAMILY SSF103378 2 441 9.55E-104 T 12-10-2018 IPR036148 MmgE/PrpD superfamily GO:0016829 VAPA_1c31220 90712631ab628198e297a02dbc5f8299 307 SUPERFAMILY SSF56281 1 307 5.8E-50 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like VAPA_1c31220 90712631ab628198e297a02dbc5f8299 307 Gene3D G3DSA:3.60.15.10 1 307 4.2E-82 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like VAPA_1c31220 90712631ab628198e297a02dbc5f8299 307 Pfam PF12706 Beta-lactamase superfamily domain 53 274 6.3E-39 T 12-10-2018 IPR001279 Metallo-beta-lactamase VAPA_1c31220 90712631ab628198e297a02dbc5f8299 307 Hamap MF_00653 Coenzyme PQQ synthesis protein B [pqqB]. 1 307 159.222 T 12-10-2018 IPR011842 Coenzyme PQQ biosynthesis protein B VAPA_1c31220 90712631ab628198e297a02dbc5f8299 307 TIGRFAM TIGR02108 PQQ_syn_pqqB: coenzyme PQQ biosynthesis protein B 2 307 1.6E-118 T 12-10-2018 IPR011842 Coenzyme PQQ biosynthesis protein B VAPA_1c10710 2ca4c1186d3fe5590c86ce4bd4f26aed 596 SUPERFAMILY SSF52091 467 579 9.03E-15 T 12-10-2018 IPR036513 STAS domain superfamily VAPA_1c10710 2ca4c1186d3fe5590c86ce4bd4f26aed 596 Pfam PF01740 STAS domain 466 576 9.8E-19 T 12-10-2018 IPR002645 STAS domain VAPA_1c10710 2ca4c1186d3fe5590c86ce4bd4f26aed 596 TIGRFAM TIGR00815 sulP: sulfate permease 33 576 1.6E-115 T 12-10-2018 IPR001902 SLC26A/SulP transporter GO:0008271|GO:0008272|GO:0016020|GO:0055085 VAPA_1c10710 2ca4c1186d3fe5590c86ce4bd4f26aed 596 Gene3D G3DSA:3.30.750.24 460 586 2.3E-32 T 12-10-2018 IPR036513 STAS domain superfamily VAPA_1c10710 2ca4c1186d3fe5590c86ce4bd4f26aed 596 Pfam PF00916 Sulfate permease family 46 413 1.2E-81 T 12-10-2018 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 VAPA_2c03730 123000c870d53a3fb12b42be582f9d58 52 Pfam PF01381 Helix-turn-helix 2 29 4.2E-5 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 VAPA_2c03730 123000c870d53a3fb12b42be582f9d58 52 Gene3D G3DSA:1.10.260.40 1 44 8.0E-7 T 12-10-2018 VAPA_2c03730 123000c870d53a3fb12b42be582f9d58 52 SUPERFAMILY SSF47413 2 34 5.33E-7 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 VAPA_1c36400 bcf73dd4306a6f3a13475c191981c073 301 Gene3D G3DSA:1.20.970.10 1 70 8.4E-28 T 12-10-2018 VAPA_1c36400 bcf73dd4306a6f3a13475c191981c073 301 SUPERFAMILY SSF52418 76 298 1.44E-35 T 12-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 VAPA_1c36400 bcf73dd4306a6f3a13475c191981c073 301 SUPERFAMILY SSF47648 6 73 8.63E-17 T 12-10-2018 IPR036320 Glycosyl transferase family 3, N-terminal domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 VAPA_1c36400 bcf73dd4306a6f3a13475c191981c073 301 Gene3D G3DSA:3.40.1030.10 72 301 1.8E-70 T 12-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 VAPA_1c36400 bcf73dd4306a6f3a13475c191981c073 301 Pfam PF02885 Glycosyl transferase family, helical bundle domain 5 65 1.1E-13 T 12-10-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 VAPA_1c42860 a905523b70183f34bfe0e98f8cd62621 145 SUPERFAMILY SSF54197 2 124 4.79E-35 T 12-10-2018 IPR036265 HIT-like superfamily VAPA_1c42860 a905523b70183f34bfe0e98f8cd62621 145 Pfam PF01230 HIT domain 16 99 8.5E-14 T 12-10-2018 IPR001310 Histidine triad (HIT) protein VAPA_1c42860 a905523b70183f34bfe0e98f8cd62621 145 Gene3D G3DSA:3.30.428.10 2 141 1.1E-34 T 12-10-2018 IPR036265 HIT-like superfamily VAPA_1c42860 a905523b70183f34bfe0e98f8cd62621 145 PIRSF PIRSF000714 4 143 2.7E-39 T 12-10-2018 IPR026026 Histidine triad hydrolase, Hint-type VAPA_1c09920 306ff5b32aa9da0b03f8c97e1b0c1a38 614 Pfam PF07730 Histidine kinase 435 470 1.2E-4 T 12-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 VAPA_1c09920 306ff5b32aa9da0b03f8c97e1b0c1a38 614 SUPERFAMILY SSF55874 492 586 7.86E-11 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_1c09920 306ff5b32aa9da0b03f8c97e1b0c1a38 614 Gene3D G3DSA:3.30.565.10 497 613 1.3E-16 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_1c23880 faa54f1f793b35f891bd7d7250339730 248 Gene3D G3DSA:3.40.1280.10 81 247 3.2E-59 T 12-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal VAPA_1c23880 faa54f1f793b35f891bd7d7250339730 248 SUPERFAMILY SSF75217 71 246 1.96E-47 T 12-10-2018 IPR029028 Alpha/beta knot methyltransferases VAPA_1c23880 faa54f1f793b35f891bd7d7250339730 248 Hamap MF_01887 23S rRNA (guanosine-2'-O-)-methyltransferase RlmB [rlmB]. 4 247 42.649 T 12-10-2018 IPR024915 23S rRNA (guanosine-2-O-)-methyltransferase RlmB VAPA_1c23880 faa54f1f793b35f891bd7d7250339730 248 SUPERFAMILY SSF55315 2 78 2.47E-15 T 12-10-2018 IPR029064 50S ribosomal protein L30e-like VAPA_1c23880 faa54f1f793b35f891bd7d7250339730 248 TIGRFAM TIGR00186 rRNA_methyl_3: RNA methyltransferase, TrmH family, group 3 5 246 7.2E-74 T 12-10-2018 IPR004441 RNA methyltransferase TrmH family GO:0006396|GO:0008173 Reactome: R-HSA-6793080 VAPA_1c23880 faa54f1f793b35f891bd7d7250339730 248 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 7 79 5.3E-13 T 12-10-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 VAPA_1c23880 faa54f1f793b35f891bd7d7250339730 248 SMART SM00967 6 82 6.2E-14 T 12-10-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 VAPA_1c23880 faa54f1f793b35f891bd7d7250339730 248 Gene3D G3DSA:3.30.1330.30 1 78 4.7E-17 T 12-10-2018 IPR029064 50S ribosomal protein L30e-like VAPA_1c23880 faa54f1f793b35f891bd7d7250339730 248 Pfam PF00588 SpoU rRNA Methylase family 100 240 2.4E-38 T 12-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 VAPA_1c27080 3323d78365fa2e0baed31a97cfe11ffb 283 TIGRFAM TIGR01469 cobA_cysG_Cterm: uroporphyrinogen-III C-methyltransferase 30 266 2.5E-81 T 12-10-2018 IPR006366 Uroporphyrin-III C-methyltransferase GO:0008168|GO:0019354 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 VAPA_1c27080 3323d78365fa2e0baed31a97cfe11ffb 283 ProSitePatterns PS00839 Uroporphyrin-III C-methyltransferase signature 1. 35 49 - T 12-10-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 VAPA_1c27080 3323d78365fa2e0baed31a97cfe11ffb 283 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 31 244 1.4E-43 T 12-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 VAPA_1c27080 3323d78365fa2e0baed31a97cfe11ffb 283 Gene3D G3DSA:3.30.950.10 146 281 1.1E-35 T 12-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 VAPA_1c27080 3323d78365fa2e0baed31a97cfe11ffb 283 ProSitePatterns PS00840 Uroporphyrin-III C-methyltransferase signature 2. 110 143 - T 12-10-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 VAPA_1c27080 3323d78365fa2e0baed31a97cfe11ffb 283 Gene3D G3DSA:3.40.1010.10 29 145 4.5E-40 T 12-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 VAPA_1c27080 3323d78365fa2e0baed31a97cfe11ffb 283 SUPERFAMILY SSF53790 27 266 2.36E-67 T 12-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 VAPA_1c50700 1e2a2f8d7a3baffb118bcd115ba90cc8 283 Pfam PF00892 EamA-like transporter family 149 278 1.1E-11 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 VAPA_1c50700 1e2a2f8d7a3baffb118bcd115ba90cc8 283 Pfam PF00892 EamA-like transporter family 7 133 1.8E-12 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 VAPA_1c50700 1e2a2f8d7a3baffb118bcd115ba90cc8 283 SUPERFAMILY SSF103481 33 137 3.66E-9 T 12-10-2018 VAPA_1c50700 1e2a2f8d7a3baffb118bcd115ba90cc8 283 SUPERFAMILY SSF103481 185 279 6.54E-9 T 12-10-2018 VAPA_1c18670 59ffb29f883308ac72d6ca0d345a22a0 383 TIGRFAM TIGR03837 efp_adjacent_2: conserved hypothetical protein, PP_1857 family 21 378 6.8E-123 T 12-10-2018 IPR016633 Uncharacterised conserved protein UCP015557 VAPA_1c18670 59ffb29f883308ac72d6ca0d345a22a0 383 PIRSF PIRSF015557 16 382 9.5E-102 T 12-10-2018 IPR016633 Uncharacterised conserved protein UCP015557 VAPA_1c18670 59ffb29f883308ac72d6ca0d345a22a0 383 Pfam PF10093 Uncharacterized protein conserved in bacteria (DUF2331) 21 377 1.4E-119 T 12-10-2018 IPR016633 Uncharacterised conserved protein UCP015557 VAPA_1c32070 d09f9a87da5fb9f4ba548d901d19a537 408 TIGRFAM TIGR02484 CitB: CitB domain protein 36 402 3.9E-122 T 12-10-2018 IPR012830 Citrate utilization protein B VAPA_1c32070 d09f9a87da5fb9f4ba548d901d19a537 408 SUPERFAMILY SSF103501 178 394 1.44E-30 T 12-10-2018 IPR036197 NarG-like superfamily VAPA_1c32070 d09f9a87da5fb9f4ba548d901d19a537 408 SUPERFAMILY SSF54862 44 121 2.22E-5 T 12-10-2018 VAPA_2c06370 773d36b66e8c79ced5bba8ce8b871957 312 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 275 287 7.6E-7 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_2c06370 773d36b66e8c79ced5bba8ce8b871957 312 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 245 259 7.6E-7 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_2c06370 773d36b66e8c79ced5bba8ce8b871957 312 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 259 275 7.6E-7 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_2c06370 773d36b66e8c79ced5bba8ce8b871957 312 Pfam PF00196 Bacterial regulatory proteins, luxR family 246 297 1.4E-12 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_2c06370 773d36b66e8c79ced5bba8ce8b871957 312 SUPERFAMILY SSF46894 227 299 4.42E-14 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 VAPA_2c06370 773d36b66e8c79ced5bba8ce8b871957 312 SUPERFAMILY SSF75516 63 230 1.18E-12 T 12-10-2018 IPR036693 Transcription factor LuxR-like, autoinducer-binding domain superfamily VAPA_2c06370 773d36b66e8c79ced5bba8ce8b871957 312 Pfam PF03472 Autoinducer binding domain 73 226 1.5E-13 T 12-10-2018 IPR005143 Transcription factor LuxR-like, autoinducer-binding domain VAPA_2c06370 773d36b66e8c79ced5bba8ce8b871957 312 Gene3D G3DSA:1.10.10.10 245 304 3.3E-16 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_2c06370 773d36b66e8c79ced5bba8ce8b871957 312 SMART SM00421 242 299 2.0E-11 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_2c06370 773d36b66e8c79ced5bba8ce8b871957 312 Gene3D G3DSA:3.30.450.80 61 213 1.4E-9 T 12-10-2018 IPR036693 Transcription factor LuxR-like, autoinducer-binding domain superfamily VAPA_1c33500 ae8ec559aa8edcb8ea0439221d27076d 191 SUPERFAMILY SSF48150 7 185 2.35E-71 T 12-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 VAPA_1c33500 ae8ec559aa8edcb8ea0439221d27076d 191 Gene3D G3DSA:1.10.340.30 7 188 1.6E-76 T 12-10-2018 VAPA_1c33500 ae8ec559aa8edcb8ea0439221d27076d 191 Pfam PF03352 Methyladenine glycosylase 11 184 1.9E-72 T 12-10-2018 IPR005019 Methyladenine glycosylase GO:0006284|GO:0008725 VAPA_1c33500 ae8ec559aa8edcb8ea0439221d27076d 191 TIGRFAM TIGR00624 tag: DNA-3-methyladenine glycosylase I 8 183 5.1E-71 T 12-10-2018 IPR004597 DNA-3-methyladenine glycosylase I GO:0006284|GO:0008725 VAPA_1c04020 3ac2070c6634f550696a9ac8224d14d0 697 SUPERFAMILY SSF53706 19 569 7.72E-151 T 12-10-2018 VAPA_1c04020 3ac2070c6634f550696a9ac8224d14d0 697 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 18 68 1.9E-7 T 12-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VAPA_1c04020 3ac2070c6634f550696a9ac8224d14d0 697 Gene3D G3DSA:3.30.2070.10 438 520 8.2E-139 T 12-10-2018 VAPA_1c04020 3ac2070c6634f550696a9ac8224d14d0 697 ProSitePatterns PS00490 Prokaryotic molybdopterin oxidoreductases signature 2. 423 440 - T 12-10-2018 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 VAPA_1c04020 3ac2070c6634f550696a9ac8224d14d0 697 Gene3D G3DSA:3.40.50.740 85 483 8.2E-139 T 12-10-2018 VAPA_1c04020 3ac2070c6634f550696a9ac8224d14d0 697 Pfam PF00384 Molybdopterin oxidoreductase 74 478 4.0E-48 T 12-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VAPA_1c04020 3ac2070c6634f550696a9ac8224d14d0 697 Gene3D G3DSA:3.40.228.10 150 543 8.2E-139 T 12-10-2018 VAPA_1c04020 3ac2070c6634f550696a9ac8224d14d0 697 Pfam PF01568 Molydopterin dinucleotide binding domain 569 678 3.6E-23 T 12-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 VAPA_1c04020 3ac2070c6634f550696a9ac8224d14d0 697 Gene3D G3DSA:2.20.25.90 13 75 1.3E-9 T 12-10-2018 VAPA_1c04020 3ac2070c6634f550696a9ac8224d14d0 697 Gene3D G3DSA:2.40.40.20 547 690 1.0E-33 T 12-10-2018 VAPA_1c04020 3ac2070c6634f550696a9ac8224d14d0 697 ProSitePatterns PS00932 Prokaryotic molybdopterin oxidoreductases signature 3. 606 633 - T 12-10-2018 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 VAPA_1c04020 3ac2070c6634f550696a9ac8224d14d0 697 SUPERFAMILY SSF50692 527 685 1.11E-38 T 12-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily VAPA_1c04020 3ac2070c6634f550696a9ac8224d14d0 697 SMART SM00926 16 71 6.8E-13 T 12-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VAPA_1c48960 16834c8d475faa60d8750f12dbfd4c2b 192 TIGRFAM TIGR01662 HAD-SF-IIIA: HAD hydrolase, family IIIA 2 141 3.5E-30 T 12-10-2018 IPR006549 HAD-superfamily hydrolase,subfamily IIIA Reactome: R-HSA-5649702 VAPA_1c48960 16834c8d475faa60d8750f12dbfd4c2b 192 PIRSF PIRSF004682 1 177 2.4E-48 T 12-10-2018 IPR004446 D,D-heptose 1,7-bisphosphate phosphatase GO:0005975|GO:0016791 VAPA_1c48960 16834c8d475faa60d8750f12dbfd4c2b 192 SUPERFAMILY SSF56784 1 179 2.8E-41 T 12-10-2018 IPR036412 HAD-like superfamily VAPA_1c48960 16834c8d475faa60d8750f12dbfd4c2b 192 TIGRFAM TIGR01656 Histidinol-ppas: histidinol-phosphate phosphatase domain 3 143 4.3E-38 T 12-10-2018 IPR006543 Histidinol-phosphate phosphatase GO:0016791 VAPA_1c48960 16834c8d475faa60d8750f12dbfd4c2b 192 Pfam PF08645 Polynucleotide kinase 3 phosphatase 23 114 8.4E-7 T 12-10-2018 IPR013954 Polynucleotide kinase 3 phosphatase Reactome: R-HSA-5649702 VAPA_1c48960 16834c8d475faa60d8750f12dbfd4c2b 192 Gene3D G3DSA:3.40.50.1000 1 185 1.5E-47 T 12-10-2018 IPR023214 HAD superfamily VAPA_1c27220 0f7b324e261875d3cdccb05789291375 169 Pfam PF00582 Universal stress protein family 1 146 2.5E-30 T 12-10-2018 IPR006016 UspA VAPA_1c27220 0f7b324e261875d3cdccb05789291375 169 PRINTS PR01438 Universal stress protein signature 124 146 3.8E-19 T 12-10-2018 IPR006015 Universal stress protein A VAPA_1c27220 0f7b324e261875d3cdccb05789291375 169 PRINTS PR01438 Universal stress protein signature 106 118 3.8E-19 T 12-10-2018 IPR006015 Universal stress protein A VAPA_1c27220 0f7b324e261875d3cdccb05789291375 169 PRINTS PR01438 Universal stress protein signature 2 20 3.8E-19 T 12-10-2018 IPR006015 Universal stress protein A VAPA_1c27220 0f7b324e261875d3cdccb05789291375 169 Gene3D G3DSA:3.40.50.620 1 147 2.5E-36 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold VAPA_1c27220 0f7b324e261875d3cdccb05789291375 169 SUPERFAMILY SSF52402 2 149 1.09E-34 T 12-10-2018 VAPA_1c20620 d0cc67824d940e4c15b711effc6c5609 235 Pfam PF02397 Bacterial sugar transferase 37 229 8.1E-61 T 12-10-2018 IPR003362 Bacterial sugar transferase VAPA_1c29640 58ee41283a1da37cf108035c99b29514 198 Pfam PF05233 PHB accumulation regulatory domain 144 183 1.8E-15 T 12-10-2018 IPR007897 PHB accumulation regulatory VAPA_1c29640 58ee41283a1da37cf108035c99b29514 198 Pfam PF05233 PHB accumulation regulatory domain 99 137 6.6E-15 T 12-10-2018 IPR007897 PHB accumulation regulatory VAPA_1c29640 58ee41283a1da37cf108035c99b29514 198 TIGRFAM TIGR01848 PHA_reg_PhaR: polyhydroxyalkanoate synthesis repressor PhaR 34 139 1.1E-42 T 12-10-2018 IPR010134 Polyhydroxyalkanoate synthesis repressor PhaR GO:0006355 VAPA_1c29640 58ee41283a1da37cf108035c99b29514 198 Pfam PF07879 PHB/PHA accumulation regulator DNA-binding domain 35 94 2.0E-29 T 12-10-2018 IPR012909 PHA accumulation regulator DNA-binding, N-terminal VAPA_1c42480 f72b275a5dbb4fdb1566e9c4e12228c3 296 SUPERFAMILY SSF51621 32 292 4.71E-96 T 12-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 VAPA_1c42480 f72b275a5dbb4fdb1566e9c4e12228c3 296 PIRSF PIRSF000388 22 295 2.1E-94 T 12-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 VAPA_1c42480 f72b275a5dbb4fdb1566e9c4e12228c3 296 Pfam PF02548 Ketopantoate hydroxymethyltransferase 31 290 2.8E-103 T 12-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 VAPA_1c42480 f72b275a5dbb4fdb1566e9c4e12228c3 296 Hamap MF_00156 3-methyl-2-oxobutanoate hydroxymethyltransferase [panB]. 31 296 40.183 T 12-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 VAPA_1c42480 f72b275a5dbb4fdb1566e9c4e12228c3 296 TIGRFAM TIGR00222 panB: 3-methyl-2-oxobutanoate hydroxymethyltransferase 38 292 2.4E-88 T 12-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 VAPA_1c42480 f72b275a5dbb4fdb1566e9c4e12228c3 296 Gene3D G3DSA:3.20.20.60 29 296 1.6E-102 T 12-10-2018 VAPA_2c06730 5b9f2246e3a1b39c9293864629dfec0e 537 SMART SM00862 23 98 5.1E-12 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 VAPA_2c06730 5b9f2246e3a1b39c9293864629dfec0e 537 Gene3D G3DSA:1.25.40.10 271 536 1.9E-24 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 VAPA_2c06730 5b9f2246e3a1b39c9293864629dfec0e 537 SUPERFAMILY SSF46894 5 98 1.19E-15 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 VAPA_2c06730 5b9f2246e3a1b39c9293864629dfec0e 537 SMART SM00028 348 381 5.3 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 VAPA_2c06730 5b9f2246e3a1b39c9293864629dfec0e 537 SMART SM00028 419 452 100.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 VAPA_2c06730 5b9f2246e3a1b39c9293864629dfec0e 537 SMART SM00028 382 415 92.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 VAPA_2c06730 5b9f2246e3a1b39c9293864629dfec0e 537 SUPERFAMILY SSF48452 288 479 5.06E-14 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 VAPA_2c06730 5b9f2246e3a1b39c9293864629dfec0e 537 Pfam PF00486 Transcriptional regulatory protein, C terminal 29 98 3.4E-12 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 VAPA_2c06730 5b9f2246e3a1b39c9293864629dfec0e 537 SUPERFAMILY SSF52964 122 218 3.92E-6 T 12-10-2018 VAPA_2c06730 5b9f2246e3a1b39c9293864629dfec0e 537 Gene3D G3DSA:1.10.10.10 2 114 2.9E-18 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c04250 bdcff63e64eb441f94eea26a5e5b1521 292 SUPERFAMILY SSF54637 12 120 2.75E-34 T 12-10-2018 IPR029069 HotDog domain superfamily VAPA_1c04250 bdcff63e64eb441f94eea26a5e5b1521 292 Pfam PF13622 Thioesterase-like superfamily 39 288 5.3E-55 T 12-10-2018 VAPA_1c04250 bdcff63e64eb441f94eea26a5e5b1521 292 SUPERFAMILY SSF54637 122 289 5.22E-52 T 12-10-2018 IPR029069 HotDog domain superfamily VAPA_1c04250 bdcff63e64eb441f94eea26a5e5b1521 292 Gene3D G3DSA:3.10.129.90 9 292 3.4E-98 T 12-10-2018 VAPA_1c41100 f03ac61d4fd872349cee4baa5ec15736 298 Pfam PF05118 Aspartyl/Asparaginyl beta-hydroxylase 68 222 2.2E-47 T 12-10-2018 IPR007803 Aspartyl/asparaginy/proline hydroxylase GO:0018193 VAPA_1c41100 f03ac61d4fd872349cee4baa5ec15736 298 Gene3D G3DSA:2.60.120.330 43 226 3.0E-44 T 12-10-2018 IPR027443 Isopenicillin N synthase-like VAPA_1c41100 f03ac61d4fd872349cee4baa5ec15736 298 SUPERFAMILY SSF51197 99 222 5.49E-19 T 12-10-2018 VAPA_1c50620 9fef61661b44084ecf5ea8be7de1b9ee 104 Gene3D G3DSA:3.30.70.260 17 104 1.0E-29 T 12-10-2018 VAPA_1c50620 9fef61661b44084ecf5ea8be7de1b9ee 104 Hamap MF_00659 UPF0250 protein YbeD [ybeD]. 16 104 21.445 T 12-10-2018 IPR007454 Uncharacterised protein family UPF0250 VAPA_1c50620 9fef61661b44084ecf5ea8be7de1b9ee 104 Pfam PF04359 Protein of unknown function (DUF493) 21 104 2.5E-29 T 12-10-2018 IPR007454 Uncharacterised protein family UPF0250 VAPA_1c50620 9fef61661b44084ecf5ea8be7de1b9ee 104 SUPERFAMILY SSF117991 18 104 4.71E-26 T 12-10-2018 IPR027471 YbeD-like domain superfamily VAPA_1c33890 9bda6e21087a3ea6bf4b180a5722e17e 422 Gene3D G3DSA:1.20.1440.320 88 245 1.9E-118 T 12-10-2018 VAPA_1c33890 9bda6e21087a3ea6bf4b180a5722e17e 422 SUPERFAMILY SSF56784 34 357 5.05E-21 T 12-10-2018 IPR036412 HAD-like superfamily VAPA_1c33890 9bda6e21087a3ea6bf4b180a5722e17e 422 Pfam PF12710 haloacid dehalogenase-like hydrolase 246 352 1.1E-6 T 12-10-2018 VAPA_1c33890 9bda6e21087a3ea6bf4b180a5722e17e 422 Gene3D G3DSA:3.40.50.1000 35 398 1.9E-118 T 12-10-2018 IPR023214 HAD superfamily VAPA_1c39990 47e6e4f1ed3dd7706dd5afc0b5f7b361 327 SUPERFAMILY SSF101898 31 295 8.37E-23 T 12-10-2018 VAPA_1c39990 47e6e4f1ed3dd7706dd5afc0b5f7b361 327 Gene3D G3DSA:2.120.10.30 18 297 2.4E-22 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like VAPA_1c24020 242b5c41d60cb239a04ab40c9070998e 502 Pfam PF01970 Tripartite tricarboxylate transporter TctA family 18 438 5.1E-130 T 12-10-2018 IPR002823 Protein of unknown function DUF112, transmembrane VAPA_1c16210 81142dde352e037302af24d0ba563690 142 Pfam PF07811 TadE-like protein 7 49 5.5E-14 T 12-10-2018 IPR012495 TadE-like VAPA_1c08340 926b75d5bc2320ba71516af5cb7c3534 365 Pfam PF00953 Glycosyl transferase family 4 81 238 2.7E-29 T 12-10-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-4549356 VAPA_1c00830 4906dfa86e0e7b5d9fe34613cac5496a 600 Pfam PF13738 Pyridine nucleotide-disulphide oxidoreductase 169 373 2.1E-18 T 12-10-2018 VAPA_1c00830 4906dfa86e0e7b5d9fe34613cac5496a 600 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 332 357 2.5E-6 T 12-10-2018 VAPA_1c00830 4906dfa86e0e7b5d9fe34613cac5496a 600 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 167 189 2.5E-6 T 12-10-2018 VAPA_1c00830 4906dfa86e0e7b5d9fe34613cac5496a 600 SUPERFAMILY SSF54427 9 112 9.0E-9 T 12-10-2018 IPR032710 NTF2-like domain superfamily VAPA_1c00830 4906dfa86e0e7b5d9fe34613cac5496a 600 Gene3D G3DSA:3.50.50.60 157 424 6.3E-61 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c00830 4906dfa86e0e7b5d9fe34613cac5496a 600 SUPERFAMILY SSF51905 167 585 1.54E-37 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c00830 4906dfa86e0e7b5d9fe34613cac5496a 600 Gene3D G3DSA:3.10.450.50 6 122 3.0E-7 T 12-10-2018 VAPA_1c00830 4906dfa86e0e7b5d9fe34613cac5496a 600 Gene3D G3DSA:3.50.50.60 448 583 3.0E-5 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c14760 c5ce59c504cf8496914ecab581a42ceb 384 Gene3D G3DSA:1.20.1250.20 13 191 9.0E-14 T 12-10-2018 VAPA_1c14760 c5ce59c504cf8496914ecab581a42ceb 384 Pfam PF07690 Major Facilitator Superfamily 15 321 9.1E-17 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 VAPA_1c14760 c5ce59c504cf8496914ecab581a42ceb 384 SUPERFAMILY SSF103473 14 376 9.42E-35 T 12-10-2018 IPR036259 MFS transporter superfamily VAPA_1c14760 c5ce59c504cf8496914ecab581a42ceb 384 Gene3D G3DSA:1.20.1250.20 196 378 3.9E-21 T 12-10-2018 VAPA_1c02580 3358a6677d1204429b7802fb6676db4a 129 SUPERFAMILY SSF52833 14 92 1.56E-7 T 12-10-2018 IPR036249 Thioredoxin-like superfamily VAPA_1c02580 3358a6677d1204429b7802fb6676db4a 129 Gene3D G3DSA:3.40.30.10 7 102 1.5E-6 T 12-10-2018 VAPA_1c11580 10987f50e8bb2b4a5018d84b6d55c57d 318 ProSitePatterns PS01054 Transaldolase signature 1. 30 38 - T 12-10-2018 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336|Reactome: R-HSA-8950505 VAPA_1c11580 10987f50e8bb2b4a5018d84b6d55c57d 318 Pfam PF00923 Transaldolase/Fructose-6-phosphate aldolase 13 311 2.7E-93 T 12-10-2018 IPR001585 Transaldolase/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336|Reactome: R-HSA-8950505 VAPA_1c11580 10987f50e8bb2b4a5018d84b6d55c57d 318 SUPERFAMILY SSF51569 1 315 1.78E-104 T 12-10-2018 VAPA_1c11580 10987f50e8bb2b4a5018d84b6d55c57d 318 TIGRFAM TIGR00874 talAB: transaldolase 2 315 3.7E-132 T 12-10-2018 IPR004730 Transaldolase type 1 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336|Reactome: R-HSA-8950505 VAPA_1c11580 10987f50e8bb2b4a5018d84b6d55c57d 318 Gene3D G3DSA:3.20.20.70 1 317 1.5E-128 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 VAPA_1c11580 10987f50e8bb2b4a5018d84b6d55c57d 318 Hamap MF_00492 Transaldolase [tal]. 1 317 46.476 T 12-10-2018 IPR004730 Transaldolase type 1 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336|Reactome: R-HSA-8950505 VAPA_1c11580 10987f50e8bb2b4a5018d84b6d55c57d 318 ProSitePatterns PS00958 Transaldolase active site. 123 140 - T 12-10-2018 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336|Reactome: R-HSA-8950505 VAPA_1c32860 c752be15ed86fdd1878c5ec255a83a90 272 Gene3D G3DSA:3.40.50.1820 13 235 7.6E-27 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c32860 c752be15ed86fdd1878c5ec255a83a90 272 Pfam PF12146 Serine aminopeptidase, S33 48 147 9.3E-10 T 12-10-2018 IPR022742 Serine aminopeptidase, S33 VAPA_1c32860 c752be15ed86fdd1878c5ec255a83a90 272 SUPERFAMILY SSF53474 14 230 2.87E-23 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_2c00740 fae679de4f99c6f18cb37bcbdb50f498 325 SUPERFAMILY SSF53850 118 283 2.99E-9 T 12-10-2018 VAPA_2c00740 fae679de4f99c6f18cb37bcbdb50f498 325 Gene3D G3DSA:3.40.190.10 122 247 2.2E-97 T 12-10-2018 VAPA_2c00740 fae679de4f99c6f18cb37bcbdb50f498 325 Gene3D G3DSA:3.40.190.150 25 315 2.2E-97 T 12-10-2018 VAPA_2c00740 fae679de4f99c6f18cb37bcbdb50f498 325 PIRSF PIRSF017082 4 324 5.0E-67 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_2c00740 fae679de4f99c6f18cb37bcbdb50f498 325 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 44 320 6.0E-72 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c05470 30afe89811494101145265ff808a7d49 534 Gene3D G3DSA:3.30.870.10 307 484 2.7E-32 T 12-10-2018 VAPA_1c05470 30afe89811494101145265ff808a7d49 534 Pfam PF13091 PLD-like domain 331 470 9.6E-20 T 12-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 VAPA_1c05470 30afe89811494101145265ff808a7d49 534 Pfam PF13091 PLD-like domain 78 231 1.5E-13 T 12-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 VAPA_1c05470 30afe89811494101145265ff808a7d49 534 SMART SM00155 172 199 0.52 T 12-10-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 VAPA_1c05470 30afe89811494101145265ff808a7d49 534 SMART SM00155 421 448 7.5E-6 T 12-10-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 VAPA_1c05470 30afe89811494101145265ff808a7d49 534 Gene3D G3DSA:3.30.870.10 65 260 5.6E-33 T 12-10-2018 VAPA_1c05470 30afe89811494101145265ff808a7d49 534 SUPERFAMILY SSF56024 62 242 1.59E-35 T 12-10-2018 VAPA_1c05470 30afe89811494101145265ff808a7d49 534 SUPERFAMILY SSF56024 327 475 2.47E-29 T 12-10-2018 VAPA_1c11430 5c87b4925e8e5d375460f16a30a6d074 326 Gene3D G3DSA:1.10.3720.10 84 312 4.1E-22 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c11430 5c87b4925e8e5d375460f16a30a6d074 326 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 112 319 6.3E-41 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 VAPA_1c11430 5c87b4925e8e5d375460f16a30a6d074 326 SUPERFAMILY SSF161098 90 304 1.62E-15 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c13080 17dac7c112670ffd0219ee153dcb7320 329 Gene3D G3DSA:3.40.50.410 90 311 3.0E-6 T 12-10-2018 IPR036465 von Willebrand factor A-like domain superfamily VAPA_1c13080 17dac7c112670ffd0219ee153dcb7320 329 SUPERFAMILY SSF53300 98 218 1.54E-8 T 12-10-2018 IPR036465 von Willebrand factor A-like domain superfamily VAPA_1c13080 17dac7c112670ffd0219ee153dcb7320 329 Pfam PF01882 Protein of unknown function DUF58 55 139 1.2E-19 T 12-10-2018 IPR002881 Domain of unknown function DUF58 VAPA_1c29280 30bee35f5119407e8b387c2d15b1afd8 638 Hamap MF_01458 ATP-dependent zinc metalloprotease FtsH [ftsH]. 8 614 37.209 T 12-10-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 VAPA_1c29280 30bee35f5119407e8b387c2d15b1afd8 638 Pfam PF06480 FtsH Extracellular 11 101 2.1E-9 T 12-10-2018 IPR011546 Peptidase M41, FtsH extracellular GO:0004222|GO:0005524|GO:0008270|GO:0016021 Reactome: R-HSA-8949664 VAPA_1c29280 30bee35f5119407e8b387c2d15b1afd8 638 ProSitePatterns PS00674 AAA-protein family signature. 300 318 - T 12-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 VAPA_1c29280 30bee35f5119407e8b387c2d15b1afd8 638 SUPERFAMILY SSF140990 411 611 5.89E-75 T 12-10-2018 IPR037219 Peptidase M41-like GO:0004222|GO:0005524|GO:0006508 Reactome: R-HSA-8949664 VAPA_1c29280 30bee35f5119407e8b387c2d15b1afd8 638 TIGRFAM TIGR01241 FtsH_fam: ATP-dependent metallopeptidase HflB 109 600 6.6E-239 T 12-10-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 VAPA_1c29280 30bee35f5119407e8b387c2d15b1afd8 638 Gene3D G3DSA:1.20.58.760 411 609 8.6E-74 T 12-10-2018 VAPA_1c29280 30bee35f5119407e8b387c2d15b1afd8 638 Gene3D G3DSA:2.40.50.920 33 108 3.8E-7 T 12-10-2018 VAPA_1c29280 30bee35f5119407e8b387c2d15b1afd8 638 Gene3D G3DSA:1.10.8.60 332 408 9.3E-30 T 12-10-2018 VAPA_1c29280 30bee35f5119407e8b387c2d15b1afd8 638 Gene3D G3DSA:3.40.50.300 145 331 1.3E-70 T 12-10-2018 VAPA_1c29280 30bee35f5119407e8b387c2d15b1afd8 638 SUPERFAMILY SSF52540 155 400 1.93E-71 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c29280 30bee35f5119407e8b387c2d15b1afd8 638 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 197 329 1.6E-45 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 VAPA_1c29280 30bee35f5119407e8b387c2d15b1afd8 638 SMART SM00382 193 332 2.8E-25 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c29280 30bee35f5119407e8b387c2d15b1afd8 638 Pfam PF01434 Peptidase family M41 391 599 4.8E-82 T 12-10-2018 IPR000642 Peptidase M41 GO:0004222|GO:0005524|GO:0006508 Reactome: R-HSA-8949664 VAPA_2c05640 127d89e99c3ae5f563492086905d6e41 369 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 220 330 4.8E-15 T 12-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 VAPA_2c05640 127d89e99c3ae5f563492086905d6e41 369 SUPERFAMILY SSF47203 215 348 1.93E-21 T 12-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 VAPA_2c05640 127d89e99c3ae5f563492086905d6e41 369 Gene3D G3DSA:1.20.140.10 208 366 1.5E-20 T 12-10-2018 VAPA_2c05640 127d89e99c3ae5f563492086905d6e41 369 SUPERFAMILY SSF56645 13 200 1.69E-15 T 12-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 VAPA_2c05640 127d89e99c3ae5f563492086905d6e41 369 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 22 103 6.6E-8 T 12-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 VAPA_2c05640 127d89e99c3ae5f563492086905d6e41 369 Gene3D G3DSA:1.10.540.10 12 105 9.0E-12 T 12-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 VAPA_2c05640 127d89e99c3ae5f563492086905d6e41 369 Gene3D G3DSA:2.40.110.10 110 207 2.0E-5 T 12-10-2018 VAPA_1c28890 41aba9acde2ed2632898611fc4f40797 354 Pfam PF02653 Branched-chain amino acid transport system / permease component 61 341 3.1E-38 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 VAPA_2c08770 feb148a7461542989ed83054ce3ba10d 233 SUPERFAMILY SSF55874 62 229 1.7E-40 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_2c08770 feb148a7461542989ed83054ce3ba10d 233 SMART SM00387 118 231 3.0E-31 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase VAPA_2c08770 feb148a7461542989ed83054ce3ba10d 233 SUPERFAMILY SSF47384 5 74 1.75E-16 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 VAPA_2c08770 feb148a7461542989ed83054ce3ba10d 233 Pfam PF00512 His Kinase A (phospho-acceptor) domain 6 73 5.6E-16 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 VAPA_2c08770 feb148a7461542989ed83054ce3ba10d 233 Gene3D G3DSA:1.10.287.130 4 76 7.5E-17 T 12-10-2018 VAPA_2c08770 feb148a7461542989ed83054ce3ba10d 233 PRINTS PR00344 Bacterial sensor protein C-terminal signature 190 208 3.3E-12 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_2c08770 feb148a7461542989ed83054ce3ba10d 233 PRINTS PR00344 Bacterial sensor protein C-terminal signature 215 228 3.3E-12 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_2c08770 feb148a7461542989ed83054ce3ba10d 233 PRINTS PR00344 Bacterial sensor protein C-terminal signature 155 169 3.3E-12 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_2c08770 feb148a7461542989ed83054ce3ba10d 233 SMART SM00388 5 73 3.5E-16 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 VAPA_2c08770 feb148a7461542989ed83054ce3ba10d 233 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 119 230 5.5E-21 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase VAPA_2c08770 feb148a7461542989ed83054ce3ba10d 233 Gene3D G3DSA:3.30.565.10 78 232 1.9E-34 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_1c23480 94361f4a6b6c5abe44e8de00edd9814d 223 SUPERFAMILY SSF46689 7 87 2.1E-19 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 VAPA_1c23480 94361f4a6b6c5abe44e8de00edd9814d 223 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 65 8.5E-16 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 VAPA_1c23480 94361f4a6b6c5abe44e8de00edd9814d 223 Gene3D G3DSA:1.10.357.10 1 204 6.0E-29 T 12-10-2018 VAPA_1c23480 94361f4a6b6c5abe44e8de00edd9814d 223 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 19 32 7.9E-10 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 VAPA_1c23480 94361f4a6b6c5abe44e8de00edd9814d 223 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 40 63 7.9E-10 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 VAPA_1c18000 e0a6e7880f0af80671faffaf0935e2d8 378 SUPERFAMILY SSF46565 2 109 5.23E-36 T 12-10-2018 IPR036869 Chaperone J-domain superfamily VAPA_1c18000 e0a6e7880f0af80671faffaf0935e2d8 378 Gene3D G3DSA:1.10.287.110 2 118 1.9E-37 T 12-10-2018 IPR036869 Chaperone J-domain superfamily VAPA_1c18000 e0a6e7880f0af80671faffaf0935e2d8 378 Gene3D G3DSA:2.60.260.20 121 253 1.1E-36 T 12-10-2018 VAPA_1c18000 e0a6e7880f0af80671faffaf0935e2d8 378 Hamap MF_01152 Chaperone protein DnaJ [dnaJ]. 3 376 40.938 T 12-10-2018 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 VAPA_1c18000 e0a6e7880f0af80671faffaf0935e2d8 378 SUPERFAMILY SSF57938 138 214 1.07E-21 T 12-10-2018 IPR036410 Heat shock protein DnaJ, cysteine-rich domain superfamily VAPA_1c18000 e0a6e7880f0af80671faffaf0935e2d8 378 SUPERFAMILY SSF49493 119 261 1.03E-17 T 12-10-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 VAPA_1c18000 e0a6e7880f0af80671faffaf0935e2d8 378 SUPERFAMILY SSF49493 263 348 2.22E-22 T 12-10-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 VAPA_1c18000 e0a6e7880f0af80671faffaf0935e2d8 378 Gene3D G3DSA:2.10.230.10 151 211 1.1E-36 T 12-10-2018 VAPA_1c18000 e0a6e7880f0af80671faffaf0935e2d8 378 ProSitePatterns PS00636 Nt-dnaJ domain signature. 50 69 - T 12-10-2018 IPR018253 DnaJ domain, conserved site VAPA_1c18000 e0a6e7880f0af80671faffaf0935e2d8 378 TIGRFAM TIGR02349 DnaJ_bact: chaperone protein DnaJ 6 353 9.9E-135 T 12-10-2018 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 VAPA_1c18000 e0a6e7880f0af80671faffaf0935e2d8 378 PRINTS PR00625 DnaJ domain signature 65 84 4.4E-32 T 12-10-2018 IPR001623 DnaJ domain VAPA_1c18000 e0a6e7880f0af80671faffaf0935e2d8 378 PRINTS PR00625 DnaJ domain signature 8 26 4.4E-32 T 12-10-2018 IPR001623 DnaJ domain VAPA_1c18000 e0a6e7880f0af80671faffaf0935e2d8 378 PRINTS PR00625 DnaJ domain signature 26 41 4.4E-32 T 12-10-2018 IPR001623 DnaJ domain VAPA_1c18000 e0a6e7880f0af80671faffaf0935e2d8 378 PRINTS PR00625 DnaJ domain signature 45 65 4.4E-32 T 12-10-2018 IPR001623 DnaJ domain VAPA_1c18000 e0a6e7880f0af80671faffaf0935e2d8 378 SMART SM00271 5 65 1.9E-31 T 12-10-2018 IPR001623 DnaJ domain VAPA_1c18000 e0a6e7880f0af80671faffaf0935e2d8 378 Pfam PF00226 DnaJ domain 6 70 2.0E-27 T 12-10-2018 IPR001623 DnaJ domain VAPA_1c18000 e0a6e7880f0af80671faffaf0935e2d8 378 Gene3D G3DSA:2.60.260.20 258 366 4.5E-30 T 12-10-2018 VAPA_1c18000 e0a6e7880f0af80671faffaf0935e2d8 378 Pfam PF00684 DnaJ central domain 151 211 4.5E-14 T 12-10-2018 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 VAPA_1c18000 e0a6e7880f0af80671faffaf0935e2d8 378 Pfam PF01556 DnaJ C terminal domain 125 337 2.8E-42 T 12-10-2018 IPR002939 Chaperone DnaJ, C-terminal VAPA_1c45070 834ee5493affa107dac9bdd933a67697 291 SUPERFAMILY SSF52540 5 163 1.95E-9 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c45070 834ee5493affa107dac9bdd933a67697 291 Hamap MF_00636 RNase adapter protein RapZ [rapZ]. 3 290 38.804 T 12-10-2018 IPR005337 RapZ-like family GO:0005524 VAPA_1c45070 834ee5493affa107dac9bdd933a67697 291 Pfam PF03668 P-loop ATPase protein family 3 289 1.3E-91 T 12-10-2018 IPR005337 RapZ-like family GO:0005524 VAPA_1c45070 834ee5493affa107dac9bdd933a67697 291 PIRSF PIRSF005052 3 291 1.3E-103 T 12-10-2018 IPR005337 RapZ-like family GO:0005524 VAPA_1c53930 7f309642b21312f7984957d0a45939c3 153 Gene3D G3DSA:3.30.700.10 14 153 4.0E-32 T 12-10-2018 VAPA_1c53930 7f309642b21312f7984957d0a45939c3 153 Pfam PF00114 Pilin (bacterial filament) 42 152 1.2E-13 T 12-10-2018 IPR001082 Fimbrial protein pilin GO:0007155|GO:0009289 VAPA_1c53930 7f309642b21312f7984957d0a45939c3 153 Pfam PF07963 Prokaryotic N-terminal methylation motif 8 34 1.0E-10 T 12-10-2018 IPR012902 Prokaryotic N-terminal methylation site VAPA_1c53930 7f309642b21312f7984957d0a45939c3 153 SUPERFAMILY SSF54523 14 152 2.56E-23 T 12-10-2018 VAPA_1c53930 7f309642b21312f7984957d0a45939c3 153 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 12 32 - T 12-10-2018 IPR012902 Prokaryotic N-terminal methylation site VAPA_1c53930 7f309642b21312f7984957d0a45939c3 153 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 11 34 1.5E-10 T 12-10-2018 IPR012902 Prokaryotic N-terminal methylation site VAPA_1c17070 6cfb7a64fb72caf0c6825bba0fdb704d 112 Pfam PF06305 Lipopolysaccharide assembly protein A domain 22 72 9.0E-10 T 12-10-2018 IPR010445 Lipopolysaccharide assembly protein A domain GO:0005887 VAPA_1c06730 1ad86e6a53398833b4e15ef94b0fa6c8 261 PRINTS PR01805 VacJ lipoprotein signature 47 60 1.4E-24 T 12-10-2018 IPR007428 MlaA lipoprotein GO:0016020 VAPA_1c06730 1ad86e6a53398833b4e15ef94b0fa6c8 261 PRINTS PR01805 VacJ lipoprotein signature 115 132 1.4E-24 T 12-10-2018 IPR007428 MlaA lipoprotein GO:0016020 VAPA_1c06730 1ad86e6a53398833b4e15ef94b0fa6c8 261 PRINTS PR01805 VacJ lipoprotein signature 151 168 1.4E-24 T 12-10-2018 IPR007428 MlaA lipoprotein GO:0016020 VAPA_1c06730 1ad86e6a53398833b4e15ef94b0fa6c8 261 PRINTS PR01805 VacJ lipoprotein signature 64 80 1.4E-24 T 12-10-2018 IPR007428 MlaA lipoprotein GO:0016020 VAPA_1c06730 1ad86e6a53398833b4e15ef94b0fa6c8 261 Pfam PF04333 MlaA lipoprotein 47 238 1.1E-68 T 12-10-2018 IPR007428 MlaA lipoprotein GO:0016020 VAPA_1c00720 213c7597a3ce66b4ed76c1713b6b454b 428 ProSitePatterns PS01192 Hydroxymethylglutaryl-coenzyme A reductases signature 3. 371 384 - T 12-10-2018 IPR023076 Hydroxymethylglutaryl-CoA reductase, class I/II, conserved site GO:0004420|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 VAPA_1c00720 213c7597a3ce66b4ed76c1713b6b454b 428 ProSitePatterns PS00318 Hydroxymethylglutaryl-coenzyme A reductases signature 2. 325 332 - T 12-10-2018 IPR023076 Hydroxymethylglutaryl-CoA reductase, class I/II, conserved site GO:0004420|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 VAPA_1c00720 213c7597a3ce66b4ed76c1713b6b454b 428 ProSitePatterns PS00066 Hydroxymethylglutaryl-coenzyme A reductases signature 1. 176 190 - T 12-10-2018 IPR023076 Hydroxymethylglutaryl-CoA reductase, class I/II, conserved site GO:0004420|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 VAPA_1c00720 213c7597a3ce66b4ed76c1713b6b454b 428 SUPERFAMILY SSF55035 111 219 3.14E-31 T 12-10-2018 IPR009023 Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding domain superfamily GO:0050662 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 VAPA_1c00720 213c7597a3ce66b4ed76c1713b6b454b 428 SUPERFAMILY SSF56542 6 427 3.14E-105 T 12-10-2018 IPR009029 Hydroxymethylglutaryl-CoA reductase, class I/II, substrate-binding domain superfamily GO:0015936|GO:0016616|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 VAPA_1c00720 213c7597a3ce66b4ed76c1713b6b454b 428 Gene3D G3DSA:1.10.8.660 376 427 2.7E-15 T 12-10-2018 VAPA_1c00720 213c7597a3ce66b4ed76c1713b6b454b 428 TIGRFAM TIGR00532 HMG_CoA_R_NAD: hydroxymethylglutaryl-CoA reductase, degradative 4 386 1.3E-131 T 12-10-2018 IPR004553 Hydroxymethylglutaryl-CoA reductase, bacterial-type GO:0015936|GO:0016616|GO:0050662 VAPA_1c00720 213c7597a3ce66b4ed76c1713b6b454b 428 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 174 192 2.4E-8 T 12-10-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 VAPA_1c00720 213c7597a3ce66b4ed76c1713b6b454b 428 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 50 71 2.4E-8 T 12-10-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 VAPA_1c00720 213c7597a3ce66b4ed76c1713b6b454b 428 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 77 97 2.4E-8 T 12-10-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 VAPA_1c00720 213c7597a3ce66b4ed76c1713b6b454b 428 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 313 334 2.4E-8 T 12-10-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 VAPA_1c00720 213c7597a3ce66b4ed76c1713b6b454b 428 Gene3D G3DSA:3.90.770.10 16 372 1.7E-136 T 12-10-2018 IPR023074 Hydroxymethylglutaryl-CoA reductase, class I/II, catalytic domain superfamily GO:0004420|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 VAPA_1c00720 213c7597a3ce66b4ed76c1713b6b454b 428 Pfam PF00368 Hydroxymethylglutaryl-coenzyme A reductase 17 386 7.6E-112 T 12-10-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 VAPA_1c00720 213c7597a3ce66b4ed76c1713b6b454b 428 Gene3D G3DSA:3.30.70.420 110 220 1.7E-136 T 12-10-2018 IPR009023 Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding domain superfamily GO:0050662 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 VAPA_1c48430 af5a6ecef993bd7d572c7e436c01158d 331 Gene3D G3DSA:3.40.50.300 27 282 3.8E-59 T 12-10-2018 VAPA_1c48430 af5a6ecef993bd7d572c7e436c01158d 331 Pfam PF00005 ABC transporter 40 184 6.6E-28 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c48430 af5a6ecef993bd7d572c7e436c01158d 331 SMART SM00382 49 234 3.4E-17 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c48430 af5a6ecef993bd7d572c7e436c01158d 331 ProSitePatterns PS00211 ABC transporters family signature. 157 171 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_1c48430 af5a6ecef993bd7d572c7e436c01158d 331 SUPERFAMILY SSF52540 34 247 2.15E-58 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c48800 c75e670490151357c98d5b7178947c2b 108 Gene3D G3DSA:3.40.30.10 1 106 1.1E-21 T 12-10-2018 VAPA_1c48800 c75e670490151357c98d5b7178947c2b 108 SUPERFAMILY SSF52833 18 101 2.61E-18 T 12-10-2018 IPR036249 Thioredoxin-like superfamily VAPA_1c48800 c75e670490151357c98d5b7178947c2b 108 Pfam PF00085 Thioredoxin 14 101 6.6E-15 T 12-10-2018 IPR013766 Thioredoxin domain GO:0045454 VAPA_1c13600 e1f2e829e62114949ac7dadeead5fb3a 354 Pfam PF00970 Oxidoreductase FAD-binding domain 115 209 1.0E-13 T 12-10-2018 IPR008333 Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain Reactome: R-HSA-1237044 VAPA_1c13600 e1f2e829e62114949ac7dadeead5fb3a 354 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 13 89 2.1E-12 T 12-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 VAPA_1c13600 e1f2e829e62114949ac7dadeead5fb3a 354 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 45 53 - T 12-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 VAPA_1c13600 e1f2e829e62114949ac7dadeead5fb3a 354 Pfam PF00175 Oxidoreductase NAD-binding domain 221 325 2.7E-18 T 12-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 VAPA_1c13600 e1f2e829e62114949ac7dadeead5fb3a 354 SUPERFAMILY SSF54292 6 99 1.21E-25 T 12-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 VAPA_1c13600 e1f2e829e62114949ac7dadeead5fb3a 354 Gene3D G3DSA:2.40.30.10 110 211 3.2E-24 T 12-10-2018 VAPA_1c13600 e1f2e829e62114949ac7dadeead5fb3a 354 SUPERFAMILY SSF63380 110 211 1.25E-22 T 12-10-2018 IPR017938 Riboflavin synthase-like beta-barrel VAPA_1c13600 e1f2e829e62114949ac7dadeead5fb3a 354 Gene3D G3DSA:3.10.20.30 2 103 8.1E-25 T 12-10-2018 IPR012675 Beta-grasp domain superfamily VAPA_1c13600 e1f2e829e62114949ac7dadeead5fb3a 354 SUPERFAMILY SSF52343 213 346 8.77E-35 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain VAPA_1c13600 e1f2e829e62114949ac7dadeead5fb3a 354 Gene3D G3DSA:3.40.50.80 212 347 8.7E-28 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain VAPA_1c13600 e1f2e829e62114949ac7dadeead5fb3a 354 PRINTS PR00410 Phenol hydroxylase reductase family signature 220 239 8.7E-22 T 12-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 VAPA_1c13600 e1f2e829e62114949ac7dadeead5fb3a 354 PRINTS PR00410 Phenol hydroxylase reductase family signature 140 152 8.7E-22 T 12-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 VAPA_1c13600 e1f2e829e62114949ac7dadeead5fb3a 354 PRINTS PR00410 Phenol hydroxylase reductase family signature 245 254 8.7E-22 T 12-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 VAPA_1c13600 e1f2e829e62114949ac7dadeead5fb3a 354 PRINTS PR00410 Phenol hydroxylase reductase family signature 312 320 8.7E-22 T 12-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 VAPA_1c13600 e1f2e829e62114949ac7dadeead5fb3a 354 PRINTS PR00410 Phenol hydroxylase reductase family signature 204 213 8.7E-22 T 12-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 VAPA_1c13600 e1f2e829e62114949ac7dadeead5fb3a 354 PRINTS PR00410 Phenol hydroxylase reductase family signature 156 163 8.7E-22 T 12-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 VAPA_1c24850 7066d6566437022b375abd2751786655 524 SUPERFAMILY SSF56024 54 238 9.42E-36 T 12-10-2018 VAPA_1c24850 7066d6566437022b375abd2751786655 524 Pfam PF13091 PLD-like domain 326 463 1.5E-20 T 12-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 VAPA_1c24850 7066d6566437022b375abd2751786655 524 Pfam PF13091 PLD-like domain 77 229 3.1E-16 T 12-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 VAPA_1c24850 7066d6566437022b375abd2751786655 524 SMART SM00155 170 197 0.038 T 12-10-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 VAPA_1c24850 7066d6566437022b375abd2751786655 524 SMART SM00155 414 441 1.3E-5 T 12-10-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 VAPA_1c24850 7066d6566437022b375abd2751786655 524 Gene3D G3DSA:3.30.870.10 70 241 8.0E-36 T 12-10-2018 VAPA_1c24850 7066d6566437022b375abd2751786655 524 SUPERFAMILY SSF56024 292 464 1.03E-29 T 12-10-2018 VAPA_1c24850 7066d6566437022b375abd2751786655 524 Gene3D G3DSA:3.30.870.10 304 491 3.0E-33 T 12-10-2018 VAPA_1c51550 8c9b4eacd00fa7eadcef5c7081a0f1ff 280 TIGRFAM TIGR01291 nodJ: ABC-2 type transporter, NodJ family 27 278 1.7E-63 T 12-10-2018 IPR005981 ABC-2 type transporter, NodJ GO:0005215|GO:0009877|GO:0015772|GO:0016020 VAPA_1c51550 8c9b4eacd00fa7eadcef5c7081a0f1ff 280 Pfam PF01061 ABC-2 type transporter 34 243 3.7E-21 T 12-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 VAPA_1c51550 8c9b4eacd00fa7eadcef5c7081a0f1ff 280 PRINTS PR00164 ABC-2 type transport system membrane protein signature 128 153 3.3E-30 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 VAPA_1c51550 8c9b4eacd00fa7eadcef5c7081a0f1ff 280 PRINTS PR00164 ABC-2 type transport system membrane protein signature 165 189 3.3E-30 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 VAPA_1c51550 8c9b4eacd00fa7eadcef5c7081a0f1ff 280 PRINTS PR00164 ABC-2 type transport system membrane protein signature 49 70 3.3E-30 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 VAPA_1c51550 8c9b4eacd00fa7eadcef5c7081a0f1ff 280 PRINTS PR00164 ABC-2 type transport system membrane protein signature 202 221 3.3E-30 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 VAPA_1c51550 8c9b4eacd00fa7eadcef5c7081a0f1ff 280 PRINTS PR00164 ABC-2 type transport system membrane protein signature 222 241 3.3E-30 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 VAPA_1c51550 8c9b4eacd00fa7eadcef5c7081a0f1ff 280 PIRSF PIRSF006648 1 279 9.6E-29 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 VAPA_1c53320 2783c372fa9d42bb9dcd3c178b80ff00 399 Gene3D G3DSA:2.30.40.10 19 398 2.3E-91 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 VAPA_1c53320 2783c372fa9d42bb9dcd3c178b80ff00 399 SUPERFAMILY SSF51556 52 365 1.44E-74 T 12-10-2018 IPR032466 Metal-dependent hydrolase VAPA_1c53320 2783c372fa9d42bb9dcd3c178b80ff00 399 Gene3D G3DSA:3.20.20.140 52 353 2.3E-91 T 12-10-2018 VAPA_1c53320 2783c372fa9d42bb9dcd3c178b80ff00 399 Pfam PF07969 Amidohydrolase family 90 370 5.8E-22 T 12-10-2018 IPR013108 Amidohydrolase 3 VAPA_1c34880 b4512c04dd52134861a667eb5e300378 270 Gene3D G3DSA:1.10.3720.10 8 263 1.5E-52 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c34880 b4512c04dd52134861a667eb5e300378 270 SUPERFAMILY SSF161098 10 269 1.57E-62 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c34880 b4512c04dd52134861a667eb5e300378 270 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 86 260 7.2E-12 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 VAPA_1c32520 bc00133af01c7dbbeef25aa5ba898991 492 Gene3D G3DSA:3.40.605.10 11 476 1.8E-167 T 12-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 VAPA_1c32520 bc00133af01c7dbbeef25aa5ba898991 492 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 250 257 - T 12-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 VAPA_1c32520 bc00133af01c7dbbeef25aa5ba898991 492 SUPERFAMILY SSF53720 6 484 7.2E-158 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 VAPA_1c32520 bc00133af01c7dbbeef25aa5ba898991 492 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 278 289 - T 12-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 VAPA_1c32520 bc00133af01c7dbbeef25aa5ba898991 492 Gene3D G3DSA:3.40.309.10 255 448 1.8E-167 T 12-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 VAPA_1c32520 bc00133af01c7dbbeef25aa5ba898991 492 Pfam PF00171 Aldehyde dehydrogenase family 21 477 1.0E-166 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 VAPA_1c27330 a354aadd48d6072c50cf3d329bf648d3 46 Pfam PF05545 Cbb3-type cytochrome oxidase component FixQ 3 46 1.9E-11 T 12-10-2018 IPR008621 Cbb3-type cytochrome oxidase component VAPA_2c11090 10fe9f538d524aa8119ecfa29da19f7e 452 Gene3D G3DSA:1.10.275.10 4 106 1.0E-33 T 12-10-2018 IPR024083 Fumarase/histidase, N-terminal VAPA_2c11090 10fe9f538d524aa8119ecfa29da19f7e 452 PRINTS PR00145 Argininosuccinate lyase family signature 101 123 9.0E-11 T 12-10-2018 VAPA_2c11090 10fe9f538d524aa8119ecfa29da19f7e 452 PRINTS PR00145 Argininosuccinate lyase family signature 232 256 9.0E-11 T 12-10-2018 VAPA_2c11090 10fe9f538d524aa8119ecfa29da19f7e 452 PRINTS PR00145 Argininosuccinate lyase family signature 277 293 9.0E-11 T 12-10-2018 VAPA_2c11090 10fe9f538d524aa8119ecfa29da19f7e 452 PRINTS PR00145 Argininosuccinate lyase family signature 142 162 9.0E-11 T 12-10-2018 VAPA_2c11090 10fe9f538d524aa8119ecfa29da19f7e 452 Pfam PF00206 Lyase 17 297 5.9E-51 T 12-10-2018 IPR022761 Fumarate lyase, N-terminal VAPA_2c11090 10fe9f538d524aa8119ecfa29da19f7e 452 SUPERFAMILY SSF48557 11 446 2.04E-113 T 12-10-2018 IPR008948 L-Aspartase-like GO:0003824 VAPA_2c11090 10fe9f538d524aa8119ecfa29da19f7e 452 TIGRFAM TIGR00928 purB: adenylosuccinate lyase 15 444 2.9E-108 T 12-10-2018 IPR004769 Adenylosuccinate lyase GO:0004018|GO:0009152 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 VAPA_2c11090 10fe9f538d524aa8119ecfa29da19f7e 452 Pfam PF10397 Adenylosuccinate lyase C-terminus 366 443 2.1E-16 T 12-10-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 VAPA_2c11090 10fe9f538d524aa8119ecfa29da19f7e 452 SMART SM00998 365 444 2.9E-22 T 12-10-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 VAPA_2c11090 10fe9f538d524aa8119ecfa29da19f7e 452 Gene3D G3DSA:1.20.200.10 107 362 1.1E-84 T 12-10-2018 VAPA_2c11090 10fe9f538d524aa8119ecfa29da19f7e 452 Gene3D G3DSA:1.10.40.30 364 450 5.9E-23 T 12-10-2018 VAPA_2c11090 10fe9f538d524aa8119ecfa29da19f7e 452 PRINTS PR00149 Fumarate lyase superfamily signature 232 259 3.5E-26 T 12-10-2018 IPR000362 Fumarate lyase family VAPA_2c11090 10fe9f538d524aa8119ecfa29da19f7e 452 PRINTS PR00149 Fumarate lyase superfamily signature 147 165 3.5E-26 T 12-10-2018 IPR000362 Fumarate lyase family VAPA_2c11090 10fe9f538d524aa8119ecfa29da19f7e 452 PRINTS PR00149 Fumarate lyase superfamily signature 102 120 3.5E-26 T 12-10-2018 IPR000362 Fumarate lyase family VAPA_2c11090 10fe9f538d524aa8119ecfa29da19f7e 452 PRINTS PR00149 Fumarate lyase superfamily signature 277 293 3.5E-26 T 12-10-2018 IPR000362 Fumarate lyase family VAPA_2c11090 10fe9f538d524aa8119ecfa29da19f7e 452 ProSitePatterns PS00163 Fumarate lyases signature. 277 286 - T 12-10-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 VAPA_1c00520 7cb3e0f96adf2599b953537483dd7036 168 SUPERFAMILY SSF109854 6 159 6.87E-27 T 12-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes VAPA_1c00520 7cb3e0f96adf2599b953537483dd7036 168 Pfam PF12867 DinB superfamily 9 150 3.7E-14 T 12-10-2018 IPR024775 DinB-like domain VAPA_1c00520 7cb3e0f96adf2599b953537483dd7036 168 Gene3D G3DSA:1.20.120.450 2 163 5.8E-28 T 12-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes VAPA_1c49860 75f24c89f18ad3d9d902b6a177fe9967 318 Gene3D G3DSA:3.40.1010.10 15 139 2.2E-42 T 12-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 VAPA_1c49860 75f24c89f18ad3d9d902b6a177fe9967 318 TIGRFAM TIGR00096 TIGR00096: 16S rRNA (cytidine(1402)-2'-O)-methyltransferase 30 303 3.5E-68 T 12-10-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 VAPA_1c49860 75f24c89f18ad3d9d902b6a177fe9967 318 SUPERFAMILY SSF53790 27 254 2.88E-66 T 12-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 VAPA_1c49860 75f24c89f18ad3d9d902b6a177fe9967 318 Gene3D G3DSA:3.30.950.10 140 263 2.3E-26 T 12-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 VAPA_1c49860 75f24c89f18ad3d9d902b6a177fe9967 318 Hamap MF_01877 Ribosomal RNA small subunit methyltransferase I [rsmI]. 29 256 32.831 T 12-10-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 VAPA_1c49860 75f24c89f18ad3d9d902b6a177fe9967 318 PIRSF PIRSF005917 17 308 2.1E-89 T 12-10-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 VAPA_1c49860 75f24c89f18ad3d9d902b6a177fe9967 318 ProSitePatterns PS01296 RsmI AdoMet-dependent methyltransferase protein family signature. 110 121 - T 12-10-2018 IPR018063 SAM-dependent methyltransferase RsmI, conserved site GO:0008168 VAPA_1c49860 75f24c89f18ad3d9d902b6a177fe9967 318 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 29 235 7.4E-32 T 12-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 VAPA_1c37680 0eb6e7f15837bc0af335e6144570aa32 172 SUPERFAMILY SSF55729 1 148 1.4E-30 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase VAPA_1c37680 0eb6e7f15837bc0af335e6144570aa32 172 Gene3D G3DSA:3.40.630.30 5 170 4.1E-39 T 12-10-2018 VAPA_1c37680 0eb6e7f15837bc0af335e6144570aa32 172 Pfam PF00583 Acetyltransferase (GNAT) family 45 145 5.1E-17 T 12-10-2018 IPR000182 GNAT domain VAPA_1c38560 d6ba3e02e12248948314ebfc5861a3eb 307 Gene3D G3DSA:3.40.190.10 147 247 1.2E-19 T 12-10-2018 VAPA_1c38560 d6ba3e02e12248948314ebfc5861a3eb 307 Pfam PF12974 ABC transporter, phosphonate, periplasmic substrate-binding protein 73 296 2.4E-28 T 12-10-2018 VAPA_1c38560 d6ba3e02e12248948314ebfc5861a3eb 307 SUPERFAMILY SSF53850 60 255 2.25E-13 T 12-10-2018 VAPA_1c38560 d6ba3e02e12248948314ebfc5861a3eb 307 Gene3D G3DSA:3.40.190.10 70 279 1.2E-19 T 12-10-2018 VAPA_1c40540 b2612d8d50c6f4d9ec3931257751b79d 408 SUPERFAMILY SSF55031 196 311 9.42E-23 T 12-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain VAPA_1c40540 b2612d8d50c6f4d9ec3931257751b79d 408 SUPERFAMILY SSF53187 6 406 2.73E-52 T 12-10-2018 VAPA_1c40540 b2612d8d50c6f4d9ec3931257751b79d 408 Gene3D G3DSA:3.30.70.360 196 316 4.2E-86 T 12-10-2018 VAPA_1c40540 b2612d8d50c6f4d9ec3931257751b79d 408 Pfam PF01546 Peptidase family M20/M25/M40 90 404 2.1E-26 T 12-10-2018 IPR002933 Peptidase M20 GO:0016787 VAPA_1c40540 b2612d8d50c6f4d9ec3931257751b79d 408 Gene3D G3DSA:3.40.630.10 28 405 4.2E-86 T 12-10-2018 VAPA_1c40540 b2612d8d50c6f4d9ec3931257751b79d 408 Pfam PF07687 Peptidase dimerisation domain 192 302 1.9E-20 T 12-10-2018 IPR011650 Peptidase M20, dimerisation domain VAPA_1c40540 b2612d8d50c6f4d9ec3931257751b79d 408 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 89 98 - T 12-10-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 VAPA_1c40540 b2612d8d50c6f4d9ec3931257751b79d 408 TIGRFAM TIGR01910 DapE-ArgE: peptidase, ArgE/DapE family 19 398 2.7E-66 T 12-10-2018 IPR010182 N-formyl-4-amino-5-aminomethyl-2-methylpyrimidine deformylase/Succinyl-diaminopimelate desuccinylase VAPA_1c14810 5297851e8f56c5b2c703c0eacd11ecf6 365 Pfam PF02504 Fatty acid synthesis protein 17 335 6.7E-101 T 12-10-2018 IPR003664 Fatty acid synthesis PlsX protein GO:0003824|GO:0006633|GO:0016747 VAPA_1c14810 5297851e8f56c5b2c703c0eacd11ecf6 365 PIRSF PIRSF002465 14 348 5.0E-123 T 12-10-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 VAPA_1c14810 5297851e8f56c5b2c703c0eacd11ecf6 365 SUPERFAMILY SSF53659 16 344 4.93E-101 T 12-10-2018 VAPA_1c14810 5297851e8f56c5b2c703c0eacd11ecf6 365 TIGRFAM TIGR00182 plsX: fatty acid/phospholipid synthesis protein PlsX 18 344 4.3E-104 T 12-10-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 VAPA_1c14810 5297851e8f56c5b2c703c0eacd11ecf6 365 Hamap MF_00019 Phosphate acyltransferase [plsX]. 1 352 142.763 T 12-10-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 VAPA_1c14810 5297851e8f56c5b2c703c0eacd11ecf6 365 Gene3D G3DSA:3.40.718.10 14 352 1.5E-120 T 12-10-2018 VAPA_1c52780 e6a027bb8620af2185c369d877cfccdb 254 SUPERFAMILY SSF100950 74 225 2.09E-27 T 12-10-2018 IPR037171 NagB/RpiA transferase-like VAPA_1c52780 e6a027bb8620af2185c369d877cfccdb 254 Pfam PF00455 DeoR C terminal sensor domain 74 227 1.9E-44 T 12-10-2018 IPR014036 DeoR C-terminal sensor domain VAPA_1c52780 e6a027bb8620af2185c369d877cfccdb 254 ProSitePatterns PS00894 DeoR-type HTH domain signature. 6 40 - T 12-10-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 VAPA_1c52780 e6a027bb8620af2185c369d877cfccdb 254 SMART SM01134 71 232 7.6E-62 T 12-10-2018 VAPA_1c52780 e6a027bb8620af2185c369d877cfccdb 254 SMART SM00420 6 58 1.4E-10 T 12-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 VAPA_1c52780 e6a027bb8620af2185c369d877cfccdb 254 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 38 56 1.2E-9 T 12-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 VAPA_1c52780 e6a027bb8620af2185c369d877cfccdb 254 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 24 38 1.2E-9 T 12-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 VAPA_1c52780 e6a027bb8620af2185c369d877cfccdb 254 SUPERFAMILY SSF46785 5 59 1.81E-11 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c52780 e6a027bb8620af2185c369d877cfccdb 254 Gene3D G3DSA:1.10.10.10 1 54 1.6E-6 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c52780 e6a027bb8620af2185c369d877cfccdb 254 Pfam PF08220 DeoR-like helix-turn-helix domain 6 57 7.6E-15 T 12-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 VAPA_1c11940 a3fb47d209136149ba3c3a812279f90b 336 Pfam PF00174 Oxidoreductase molybdopterin binding domain 114 269 1.1E-31 T 12-10-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 VAPA_1c11940 a3fb47d209136149ba3c3a812279f90b 336 SUPERFAMILY SSF56524 79 332 5.62E-94 T 12-10-2018 IPR036374 Oxidoreductase, molybdopterin-binding domain superfamily GO:0042128 Reactome: R-HSA-1614517 VAPA_1c11940 a3fb47d209136149ba3c3a812279f90b 336 Gene3D G3DSA:3.90.420.10 75 336 5.5E-108 T 12-10-2018 IPR036374 Oxidoreductase, molybdopterin-binding domain superfamily GO:0042128 Reactome: R-HSA-1614517 VAPA_1c11940 a3fb47d209136149ba3c3a812279f90b 336 Hamap MF_01206 Protein-methionine-sulfoxide reductase catalytic subunit MsrP [msrP]. 16 336 54.894 T 12-10-2018 IPR022867 Protein-methionine-sulfoxide reductase subunit MsrP GO:0016667|GO:0030091|GO:0043546|GO:0055114 VAPA_1c21380 9d1e897e20fa3170332a307489112ee9 183 ProSitePatterns PS00893 Nudix box signature. 77 98 - T 12-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 VAPA_1c21380 9d1e897e20fa3170332a307489112ee9 183 Pfam PF14803 Nudix N-terminal 8 42 6.9E-15 T 12-10-2018 IPR029401 Nudix hydrolase, N-terminal KEGG: 00230+3.6.1.13|KEGG: 00740+3.6.1.18 VAPA_1c21380 9d1e897e20fa3170332a307489112ee9 183 Gene3D G3DSA:3.90.79.10 43 181 1.1E-34 T 12-10-2018 VAPA_1c21380 9d1e897e20fa3170332a307489112ee9 183 Gene3D G3DSA:2.20.70.10 6 42 2.0E-13 T 12-10-2018 VAPA_1c21380 9d1e897e20fa3170332a307489112ee9 183 SUPERFAMILY SSF55811 8 170 1.76E-35 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 VAPA_1c21380 9d1e897e20fa3170332a307489112ee9 183 Pfam PF00293 NUDIX domain 48 150 9.6E-13 T 12-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 VAPA_1c07360 845c7ebe2d17b3b49ca1e2806df924b3 127 TIGRFAM TIGR00964 secE_bact: preprotein translocase, SecE subunit 69 118 1.2E-14 T 12-10-2018 IPR005807 SecE subunit of protein translocation complex, bacterial-like GO:0009306|GO:0015450|GO:0016021 VAPA_1c07360 845c7ebe2d17b3b49ca1e2806df924b3 127 Gene3D G3DSA:1.20.5.1030 65 122 1.7E-14 T 12-10-2018 IPR038379 SecE superfamily VAPA_1c07360 845c7ebe2d17b3b49ca1e2806df924b3 127 PRINTS PR01650 Bacterial translocase SecE signature 43 64 1.2E-10 T 12-10-2018 IPR005807 SecE subunit of protein translocation complex, bacterial-like GO:0009306|GO:0015450|GO:0016021 VAPA_1c07360 845c7ebe2d17b3b49ca1e2806df924b3 127 PRINTS PR01650 Bacterial translocase SecE signature 64 84 1.2E-10 T 12-10-2018 IPR005807 SecE subunit of protein translocation complex, bacterial-like GO:0009306|GO:0015450|GO:0016021 VAPA_1c07360 845c7ebe2d17b3b49ca1e2806df924b3 127 PRINTS PR01650 Bacterial translocase SecE signature 88 108 1.2E-10 T 12-10-2018 IPR005807 SecE subunit of protein translocation complex, bacterial-like GO:0009306|GO:0015450|GO:0016021 VAPA_1c07360 845c7ebe2d17b3b49ca1e2806df924b3 127 Pfam PF00584 SecE/Sec61-gamma subunits of protein translocation complex 68 118 2.3E-16 T 12-10-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 VAPA_1c41000 d06c6c4d67b8c33b430e1a0351a0fa5f 421 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 6 414 9.0E-102 T 12-10-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit VAPA_1c41000 d06c6c4d67b8c33b430e1a0351a0fa5f 421 PIRSF PIRSF006066 1 421 8.1E-125 T 12-10-2018 IPR004681 TRAP transporter large membrane protein DctM GO:0016021 VAPA_1c41000 d06c6c4d67b8c33b430e1a0351a0fa5f 421 TIGRFAM TIGR00786 dctM: TRAP transporter, DctM subunit 14 419 1.6E-111 T 12-10-2018 IPR004681 TRAP transporter large membrane protein DctM GO:0016021 VAPA_2c11420 038890fb727a461e4d89e7fb8e25fa4e 465 SUPERFAMILY SSF75304 4 464 3.27E-128 T 12-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 VAPA_2c11420 038890fb727a461e4d89e7fb8e25fa4e 465 Gene3D G3DSA:3.90.1300.10 5 465 1.1E-128 T 12-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 VAPA_2c11420 038890fb727a461e4d89e7fb8e25fa4e 465 Pfam PF01425 Amidase 26 445 1.6E-104 T 12-10-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 VAPA_2c11420 038890fb727a461e4d89e7fb8e25fa4e 465 ProSitePatterns PS00571 Amidases signature. 152 183 - T 12-10-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 VAPA_1c44210 909c7b4f7b6a836fdbb465fac935c266 668 Pfam PF05170 AsmA family 11 553 1.7E-101 T 12-10-2018 IPR007844 AsmA VAPA_1c24000 4ea8503e72369b0f08da54341b7a4adb 335 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 60 331 2.0E-49 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c24000 4ea8503e72369b0f08da54341b7a4adb 335 Gene3D G3DSA:3.40.190.10 135 261 6.1E-83 T 12-10-2018 VAPA_1c24000 4ea8503e72369b0f08da54341b7a4adb 335 SUPERFAMILY SSF53850 126 297 5.07E-11 T 12-10-2018 VAPA_1c24000 4ea8503e72369b0f08da54341b7a4adb 335 PIRSF PIRSF017082 6 335 1.1E-86 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c24000 4ea8503e72369b0f08da54341b7a4adb 335 Gene3D G3DSA:3.40.190.150 40 323 6.1E-83 T 12-10-2018 VAPA_1c44070 441c60483c07a534a45402adbbfb4f45 216 SUPERFAMILY SSF52540 16 209 2.13E-35 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c44070 441c60483c07a534a45402adbbfb4f45 216 Hamap MF_01389 Urease accessory protein UreG [ureG]. 16 214 46.503 T 12-10-2018 IPR004400 Urease accessory protein UreG GO:0003924|GO:0006807|GO:0016151 VAPA_1c44070 441c60483c07a534a45402adbbfb4f45 216 TIGRFAM TIGR00101 ureG: urease accessory protein UreG 18 213 7.9E-99 T 12-10-2018 IPR004400 Urease accessory protein UreG GO:0003924|GO:0006807|GO:0016151 VAPA_1c44070 441c60483c07a534a45402adbbfb4f45 216 Gene3D G3DSA:3.40.50.300 18 214 4.5E-51 T 12-10-2018 VAPA_1c44070 441c60483c07a534a45402adbbfb4f45 216 PIRSF PIRSF005624 4 215 4.4E-48 T 12-10-2018 IPR012202 [NiFe]-hydrogenase/urease maturation factor, Ni2-binding GTPase GO:0003924|GO:0016151 VAPA_1c44070 441c60483c07a534a45402adbbfb4f45 216 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 20 189 4.3E-38 T 12-10-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain VAPA_1c36280 84a5707bc7a9b26e35d8d540d68c1f73 252 SUPERFAMILY SSF53474 17 219 2.75E-16 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c36280 84a5707bc7a9b26e35d8d540d68c1f73 252 Pfam PF00756 Putative esterase 58 210 3.8E-6 T 12-10-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 VAPA_1c36280 84a5707bc7a9b26e35d8d540d68c1f73 252 Gene3D G3DSA:3.40.50.1820 6 221 1.6E-13 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_2c13190 380b4110cfe059dc4fa37aa13d483829 238 Pfam PF05857 TraX protein 26 232 1.0E-38 T 12-10-2018 IPR008875 TraX VAPA_1c38080 3ffcc01eacf105be22593ce27d9c9c52 355 SMART SM00382 28 212 4.0E-14 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c38080 3ffcc01eacf105be22593ce27d9c9c52 355 SUPERFAMILY SSF52540 4 242 3.8E-85 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c38080 3ffcc01eacf105be22593ce27d9c9c52 355 Gene3D G3DSA:3.40.50.300 3 221 9.4E-66 T 12-10-2018 VAPA_1c38080 3ffcc01eacf105be22593ce27d9c9c52 355 Gene3D G3DSA:2.40.50.940 222 347 1.6E-29 T 12-10-2018 VAPA_1c38080 3ffcc01eacf105be22593ce27d9c9c52 355 Gene3D G3DSA:2.40.50.140 285 338 1.6E-29 T 12-10-2018 VAPA_1c38080 3ffcc01eacf105be22593ce27d9c9c52 355 Pfam PF08402 TOBE domain 279 346 4.8E-8 T 12-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 VAPA_1c38080 3ffcc01eacf105be22593ce27d9c9c52 355 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_1c38080 3ffcc01eacf105be22593ce27d9c9c52 355 SUPERFAMILY SSF50331 236 354 1.17E-28 T 12-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal VAPA_1c38080 3ffcc01eacf105be22593ce27d9c9c52 355 Pfam PF00005 ABC transporter 20 161 5.1E-32 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c18240 54ae383db0b337b77ae89f371363d9d5 510 Gene3D G3DSA:2.20.200.10 109 389 5.1E-126 T 12-10-2018 VAPA_1c18240 54ae383db0b337b77ae89f371363d9d5 510 Gene3D G3DSA:1.20.1600.10 64 499 5.1E-126 T 12-10-2018 VAPA_1c18240 54ae383db0b337b77ae89f371363d9d5 510 SUPERFAMILY SSF56954 5 501 7.98E-98 T 12-10-2018 VAPA_1c18240 54ae383db0b337b77ae89f371363d9d5 510 Pfam PF02321 Outer membrane efflux protein 72 279 1.7E-24 T 12-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 VAPA_1c18240 54ae383db0b337b77ae89f371363d9d5 510 Pfam PF02321 Outer membrane efflux protein 319 498 7.8E-27 T 12-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 VAPA_1c18240 54ae383db0b337b77ae89f371363d9d5 510 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 12 499 2.0E-96 T 12-10-2018 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0016020|GO:0022857|GO:0055085 VAPA_2c12100 098b4abc676603ab94672de9275c67d5 192 Gene3D G3DSA:1.10.10.10 1 149 1.9E-26 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_2c12100 098b4abc676603ab94672de9275c67d5 192 ProSitePatterns PS01117 MarR-type HTH domain signature. 73 107 - T 12-10-2018 IPR023187 Transcriptional regulator MarR-type, conserved site VAPA_2c12100 098b4abc676603ab94672de9275c67d5 192 Pfam PF12802 MarR family 40 97 3.1E-8 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 VAPA_2c12100 098b4abc676603ab94672de9275c67d5 192 SMART SM00347 34 134 7.3E-16 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 VAPA_2c12100 098b4abc676603ab94672de9275c67d5 192 SUPERFAMILY SSF46785 6 150 1.43E-24 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c48680 7aa35aaa26289a92c6ae009b8fabb5c7 336 Gene3D G3DSA:3.40.190.150 41 326 1.1E-101 T 12-10-2018 VAPA_1c48680 7aa35aaa26289a92c6ae009b8fabb5c7 336 SUPERFAMILY SSF53850 126 297 6.18E-12 T 12-10-2018 VAPA_1c48680 7aa35aaa26289a92c6ae009b8fabb5c7 336 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 60 332 1.1E-75 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c48680 7aa35aaa26289a92c6ae009b8fabb5c7 336 Gene3D G3DSA:3.40.190.10 139 261 1.1E-101 T 12-10-2018 VAPA_1c48680 7aa35aaa26289a92c6ae009b8fabb5c7 336 PIRSF PIRSF017082 4 335 4.2E-73 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c43180 38a6ad55d978c6f63efbf2b95f5a24f8 401 Pfam PF02120 Flagellar hook-length control protein FliK 326 395 9.6E-15 T 12-10-2018 IPR021136 Flagellar hook-length control protein-like, C-terminal VAPA_1c30830 96d0c67a1925bfd297602f1448f8c5ff 154 SUPERFAMILY SSF52833 7 152 1.71E-44 T 12-10-2018 IPR036249 Thioredoxin-like superfamily VAPA_1c30830 96d0c67a1925bfd297602f1448f8c5ff 154 PIRSF PIRSF000216 1 154 1.2E-44 T 12-10-2018 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VAPA_1c30830 96d0c67a1925bfd297602f1448f8c5ff 154 Gene3D G3DSA:1.10.10.1590 4 68 2.4E-10 T 12-10-2018 VAPA_1c30830 96d0c67a1925bfd297602f1448f8c5ff 154 Pfam PF01257 Thioredoxin-like [2Fe-2S] ferredoxin 9 150 1.5E-39 T 12-10-2018 VAPA_1c30830 96d0c67a1925bfd297602f1448f8c5ff 154 Gene3D G3DSA:3.40.30.10 69 154 1.9E-22 T 12-10-2018 VAPA_1c05460 ca774cebd570eb0ac97fac480a6d9e7f 530 ProSitePatterns PS00717 Sigma-54 factors family signature 1. 418 437 - T 12-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 VAPA_1c05460 ca774cebd570eb0ac97fac480a6d9e7f 530 ProSitePatterns PS00718 Sigma-54 factors family signature 2. 509 516 - T 12-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 VAPA_1c05460 ca774cebd570eb0ac97fac480a6d9e7f 530 Pfam PF00309 Sigma-54 factor, Activator interacting domain (AID) 5 48 3.1E-18 T 12-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 VAPA_1c05460 ca774cebd570eb0ac97fac480a6d9e7f 530 Pfam PF04552 Sigma-54, DNA binding domain 372 528 8.2E-63 T 12-10-2018 IPR007634 RNA polymerase sigma factor 54, DNA-binding VAPA_1c05460 ca774cebd570eb0ac97fac480a6d9e7f 530 TIGRFAM TIGR02395 rpoN_sigma: RNA polymerase sigma-54 factor 10 528 2.4E-127 T 12-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 VAPA_1c05460 ca774cebd570eb0ac97fac480a6d9e7f 530 Gene3D G3DSA:1.10.10.1330 157 281 1.2E-16 T 12-10-2018 IPR038709 RNA polymerase sigma-54 factor, core-binding domain superfamily VAPA_1c05460 ca774cebd570eb0ac97fac480a6d9e7f 530 PIRSF PIRSF000774 1 530 3.8E-149 T 12-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 VAPA_1c05460 ca774cebd570eb0ac97fac480a6d9e7f 530 Pfam PF04963 Sigma-54 factor, core binding domain 151 358 6.3E-50 T 12-10-2018 IPR007046 RNA polymerase sigma factor 54, core-binding domain GO:0003677|GO:0006352 VAPA_1c05460 ca774cebd570eb0ac97fac480a6d9e7f 530 PRINTS PR00045 Sigma-54 factor signature 430 442 1.0E-27 T 12-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 VAPA_1c05460 ca774cebd570eb0ac97fac480a6d9e7f 530 PRINTS PR00045 Sigma-54 factor signature 231 248 1.0E-27 T 12-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 VAPA_1c05460 ca774cebd570eb0ac97fac480a6d9e7f 530 PRINTS PR00045 Sigma-54 factor signature 504 522 1.0E-27 T 12-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 VAPA_1c05460 ca774cebd570eb0ac97fac480a6d9e7f 530 PRINTS PR00045 Sigma-54 factor signature 446 457 1.0E-27 T 12-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 VAPA_1c05460 ca774cebd570eb0ac97fac480a6d9e7f 530 Gene3D G3DSA:1.10.10.60 471 528 4.1E-21 T 12-10-2018 VAPA_1c20500 27ac1c4e45bce9d089d6524078b69cc6 327 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 50 322 6.1E-75 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c20500 27ac1c4e45bce9d089d6524078b69cc6 327 Gene3D G3DSA:3.40.190.150 31 315 4.4E-106 T 12-10-2018 VAPA_1c20500 27ac1c4e45bce9d089d6524078b69cc6 327 PIRSF PIRSF017082 1 326 4.0E-80 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c20500 27ac1c4e45bce9d089d6524078b69cc6 327 SUPERFAMILY SSF53850 54 288 1.95E-12 T 12-10-2018 VAPA_1c20500 27ac1c4e45bce9d089d6524078b69cc6 327 Gene3D G3DSA:3.40.190.10 128 251 4.4E-106 T 12-10-2018 VAPA_1c39910 dcf27933e6bb9287942f333cb19e6fbb 326 Gene3D G3DSA:3.40.190.10 114 214 3.0E-65 T 12-10-2018 VAPA_1c39910 dcf27933e6bb9287942f333cb19e6fbb 326 SUPERFAMILY SSF53850 58 314 2.17E-29 T 12-10-2018 VAPA_1c39910 dcf27933e6bb9287942f333cb19e6fbb 326 Gene3D G3DSA:3.40.190.10 41 313 3.0E-65 T 12-10-2018 VAPA_1c39910 dcf27933e6bb9287942f333cb19e6fbb 326 Pfam PF13379 NMT1-like family 60 259 3.8E-9 T 12-10-2018 VAPA_1c31930 7935caa64114fe4ff273a1983f005237 183 SUPERFAMILY SSF52218 1 180 1.22E-41 T 12-10-2018 IPR029039 Flavoprotein-like superfamily VAPA_1c31930 7935caa64114fe4ff273a1983f005237 183 Gene3D G3DSA:3.40.50.360 1 182 1.8E-56 T 12-10-2018 IPR029039 Flavoprotein-like superfamily VAPA_1c31930 7935caa64114fe4ff273a1983f005237 183 ProSitePatterns PS00201 Flavodoxin signature. 6 22 - T 12-10-2018 IPR001226 Flavodoxin, conserved site GO:0009055|GO:0010181 VAPA_1c31930 7935caa64114fe4ff273a1983f005237 183 Pfam PF03358 NADPH-dependent FMN reductase 47 108 4.8E-8 T 12-10-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 VAPA_2c06560 fdf8e161e7e45aec2976adf34124651c 251 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 8 188 1.5E-5 T 12-10-2018 VAPA_2c06560 fdf8e161e7e45aec2976adf34124651c 251 SUPERFAMILY SSF51735 8 250 1.75E-76 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_2c06560 fdf8e161e7e45aec2976adf34124651c 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 137 145 1.8E-16 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c06560 fdf8e161e7e45aec2976adf34124651c 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 1.8E-16 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c06560 fdf8e161e7e45aec2976adf34124651c 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 157 176 1.8E-16 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c06560 fdf8e161e7e45aec2976adf34124651c 251 Gene3D G3DSA:3.40.50.720 2 251 9.5E-78 T 12-10-2018 VAPA_2c06560 fdf8e161e7e45aec2976adf34124651c 251 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 17 249 1.2E-60 T 12-10-2018 VAPA_2c06560 fdf8e161e7e45aec2976adf34124651c 251 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 144 172 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 VAPA_2c06560 fdf8e161e7e45aec2976adf34124651c 251 TIGRFAM TIGR01829 AcAcCoA_reduct: acetoacetyl-CoA reductase 9 250 4.7E-108 T 12-10-2018 IPR011283 Acetoacetyl-CoA reductase GO:0005737|GO:0018454|GO:0042619|GO:0055114 KEGG: 00630+1.1.1.36|KEGG: 00650+1.1.1.36|MetaCyc: PWY-5676|MetaCyc: PWY-5741|MetaCyc: PWY-7216|MetaCyc: PWY-7948 VAPA_2c06560 fdf8e161e7e45aec2976adf34124651c 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 1.5E-48 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c06560 fdf8e161e7e45aec2976adf34124651c 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 212 232 1.5E-48 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c06560 fdf8e161e7e45aec2976adf34124651c 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 1.5E-48 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c06560 fdf8e161e7e45aec2976adf34124651c 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 1.5E-48 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c06560 fdf8e161e7e45aec2976adf34124651c 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 1.5E-48 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c06560 fdf8e161e7e45aec2976adf34124651c 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 1.5E-48 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c00320 34f1abd12ef69e765512edc89ad880d0 160 SUPERFAMILY SSF55729 3 144 2.16E-33 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase VAPA_1c00320 34f1abd12ef69e765512edc89ad880d0 160 Pfam PF00583 Acetyltransferase (GNAT) family 38 131 6.7E-19 T 12-10-2018 IPR000182 GNAT domain VAPA_1c00320 34f1abd12ef69e765512edc89ad880d0 160 Gene3D G3DSA:3.40.630.30 2 159 1.8E-34 T 12-10-2018 VAPA_1c08290 c0979cc78f12cb00483e980a57ff97e9 653 SUPERFAMILY SSF53448 131 315 3.0E-12 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases VAPA_1c08290 c0979cc78f12cb00483e980a57ff97e9 653 Gene3D G3DSA:3.90.550.10 353 589 1.3E-45 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases VAPA_1c08290 c0979cc78f12cb00483e980a57ff97e9 653 Gene3D G3DSA:3.90.550.10 129 351 2.7E-16 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases VAPA_1c08290 c0979cc78f12cb00483e980a57ff97e9 653 Pfam PF00535 Glycosyl transferase family 2 362 487 1.5E-19 T 12-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 VAPA_1c08290 c0979cc78f12cb00483e980a57ff97e9 653 SUPERFAMILY SSF53448 355 608 1.78E-47 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases VAPA_1c27850 1e2e64c9f018f2dd14ad3c27b24b21cd 276 Gene3D G3DSA:1.10.10.60 170 275 2.1E-22 T 12-10-2018 VAPA_1c27850 1e2e64c9f018f2dd14ad3c27b24b21cd 276 Pfam PF12833 Helix-turn-helix domain 198 272 7.9E-20 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 VAPA_1c27850 1e2e64c9f018f2dd14ad3c27b24b21cd 276 SUPERFAMILY SSF46689 173 223 5.82E-5 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 VAPA_1c27850 1e2e64c9f018f2dd14ad3c27b24b21cd 276 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 226 267 - T 12-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 VAPA_1c27850 1e2e64c9f018f2dd14ad3c27b24b21cd 276 SUPERFAMILY SSF46689 225 273 2.42E-9 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 VAPA_1c27850 1e2e64c9f018f2dd14ad3c27b24b21cd 276 SMART SM00342 189 271 1.5E-20 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 VAPA_1c27850 1e2e64c9f018f2dd14ad3c27b24b21cd 276 Pfam PF02311 AraC-like ligand binding domain 19 147 1.3E-18 T 12-10-2018 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 VAPA_1c27850 1e2e64c9f018f2dd14ad3c27b24b21cd 276 SUPERFAMILY SSF51215 31 142 1.1E-12 T 12-10-2018 IPR037923 Transcription regulator HTH-like VAPA_1c12410 e016fd2dca104eaeab410117ac02a294 271 TIGRFAM TIGR00945 tatC: twin arginine-targeting protein translocase TatC 23 241 9.6E-56 T 12-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 VAPA_1c12410 e016fd2dca104eaeab410117ac02a294 271 Pfam PF00902 Sec-independent protein translocase protein (TatC) 24 236 2.7E-55 T 12-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 VAPA_1c12410 e016fd2dca104eaeab410117ac02a294 271 Hamap MF_00902 Sec-independent protein translocase protein TatC [tatC]. 10 255 14.859 T 12-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 VAPA_1c12410 e016fd2dca104eaeab410117ac02a294 271 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 21 48 3.8E-35 T 12-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 VAPA_1c12410 e016fd2dca104eaeab410117ac02a294 271 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 100 118 3.8E-35 T 12-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 VAPA_1c12410 e016fd2dca104eaeab410117ac02a294 271 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 118 144 3.8E-35 T 12-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 VAPA_1c12410 e016fd2dca104eaeab410117ac02a294 271 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 169 197 3.8E-35 T 12-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 VAPA_2c08090 3a1b8dfbe526ae1ba0e11be558aaefa8 335 Gene3D G3DSA:2.40.30.10 101 196 5.7E-21 T 12-10-2018 VAPA_2c08090 3a1b8dfbe526ae1ba0e11be558aaefa8 335 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 37 45 - T 12-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 VAPA_2c08090 3a1b8dfbe526ae1ba0e11be558aaefa8 335 SUPERFAMILY SSF52343 199 329 2.88E-40 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain VAPA_2c08090 3a1b8dfbe526ae1ba0e11be558aaefa8 335 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 11 80 3.1E-14 T 12-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 VAPA_2c08090 3a1b8dfbe526ae1ba0e11be558aaefa8 335 SUPERFAMILY SSF54292 1 87 1.31E-24 T 12-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 VAPA_2c08090 3a1b8dfbe526ae1ba0e11be558aaefa8 335 Pfam PF00970 Oxidoreductase FAD-binding domain 104 196 3.2E-8 T 12-10-2018 IPR008333 Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain Reactome: R-HSA-1237044 VAPA_2c08090 3a1b8dfbe526ae1ba0e11be558aaefa8 335 Gene3D G3DSA:3.40.50.80 198 330 5.7E-36 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain VAPA_2c08090 3a1b8dfbe526ae1ba0e11be558aaefa8 335 SUPERFAMILY SSF63380 103 195 1.04E-19 T 12-10-2018 IPR017938 Riboflavin synthase-like beta-barrel VAPA_2c08090 3a1b8dfbe526ae1ba0e11be558aaefa8 335 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 242 253 7.1E-12 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 VAPA_2c08090 3a1b8dfbe526ae1ba0e11be558aaefa8 335 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 146 153 7.1E-12 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 VAPA_2c08090 3a1b8dfbe526ae1ba0e11be558aaefa8 335 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 205 224 7.1E-12 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 VAPA_2c08090 3a1b8dfbe526ae1ba0e11be558aaefa8 335 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 130 140 7.1E-12 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 VAPA_2c08090 3a1b8dfbe526ae1ba0e11be558aaefa8 335 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 230 239 7.1E-12 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 VAPA_2c08090 3a1b8dfbe526ae1ba0e11be558aaefa8 335 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 295 303 7.1E-12 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 VAPA_2c08090 3a1b8dfbe526ae1ba0e11be558aaefa8 335 PRINTS PR00410 Phenol hydroxylase reductase family signature 189 198 8.1E-20 T 12-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 VAPA_2c08090 3a1b8dfbe526ae1ba0e11be558aaefa8 335 PRINTS PR00410 Phenol hydroxylase reductase family signature 205 224 8.1E-20 T 12-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 VAPA_2c08090 3a1b8dfbe526ae1ba0e11be558aaefa8 335 PRINTS PR00410 Phenol hydroxylase reductase family signature 146 153 8.1E-20 T 12-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 VAPA_2c08090 3a1b8dfbe526ae1ba0e11be558aaefa8 335 PRINTS PR00410 Phenol hydroxylase reductase family signature 230 239 8.1E-20 T 12-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 VAPA_2c08090 3a1b8dfbe526ae1ba0e11be558aaefa8 335 PRINTS PR00410 Phenol hydroxylase reductase family signature 295 303 8.1E-20 T 12-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 VAPA_2c08090 3a1b8dfbe526ae1ba0e11be558aaefa8 335 PRINTS PR00410 Phenol hydroxylase reductase family signature 130 142 8.1E-20 T 12-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 VAPA_2c08090 3a1b8dfbe526ae1ba0e11be558aaefa8 335 Pfam PF00175 Oxidoreductase NAD-binding domain 206 309 3.4E-26 T 12-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 VAPA_2c08090 3a1b8dfbe526ae1ba0e11be558aaefa8 335 Gene3D G3DSA:3.10.20.30 2 92 2.0E-25 T 12-10-2018 IPR012675 Beta-grasp domain superfamily VAPA_1c45470 74a41b7d5c78e57ec46acd4b944d6faa 353 SMART SM00963 63 139 1.3E-16 T 12-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 VAPA_1c45470 74a41b7d5c78e57ec46acd4b944d6faa 353 SMART SM00962 153 353 2.7E-108 T 12-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 VAPA_1c45470 74a41b7d5c78e57ec46acd4b944d6faa 353 Gene3D G3DSA:3.40.50.300 153 341 1.9E-104 T 12-10-2018 VAPA_1c45470 74a41b7d5c78e57ec46acd4b944d6faa 353 SUPERFAMILY SSF52540 153 348 1.03E-46 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c45470 74a41b7d5c78e57ec46acd4b944d6faa 353 Pfam PF00448 SRP54-type protein, GTPase domain 153 352 3.2E-70 T 12-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 VAPA_1c45470 74a41b7d5c78e57ec46acd4b944d6faa 353 SUPERFAMILY SSF47364 58 133 1.96E-17 T 12-10-2018 IPR036225 SRP/SRP receptor, N-terminal Reactome: R-HSA-1799339 VAPA_1c45470 74a41b7d5c78e57ec46acd4b944d6faa 353 TIGRFAM TIGR00064 ftsY: signal recognition particle-docking protein FtsY 83 351 1.1E-97 T 12-10-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 VAPA_1c45470 74a41b7d5c78e57ec46acd4b944d6faa 353 SMART SM00382 152 303 0.0015 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c45470 74a41b7d5c78e57ec46acd4b944d6faa 353 Pfam PF02881 SRP54-type protein, helical bundle domain 71 134 1.1E-10 T 12-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 VAPA_1c45470 74a41b7d5c78e57ec46acd4b944d6faa 353 Gene3D G3DSA:1.20.120.140 60 351 1.9E-104 T 12-10-2018 VAPA_1c45470 74a41b7d5c78e57ec46acd4b944d6faa 353 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 326 339 - T 12-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 VAPA_1c45470 74a41b7d5c78e57ec46acd4b944d6faa 353 Hamap MF_00920 Signal recognition particle receptor FtsY [ftsY]. 82 353 57.859 T 12-10-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 VAPA_1c21000 4cb3d28d7076d453f44782c9d11a61d7 630 Pfam PF05157 Type II secretion system (T2SS), protein E, N-terminal domain 61 151 8.4E-16 T 12-10-2018 IPR007831 General secretory system II, protein E, N-terminal VAPA_1c21000 4cb3d28d7076d453f44782c9d11a61d7 630 Gene3D G3DSA:3.30.300.160 82 164 6.5E-6 T 12-10-2018 VAPA_1c21000 4cb3d28d7076d453f44782c9d11a61d7 630 Pfam PF11203 Putative type VII ESX secretion system translocon, EccE 484 552 1.2E-4 T 12-10-2018 IPR021368 Type VII secretion system protein EccE VAPA_1c21000 4cb3d28d7076d453f44782c9d11a61d7 630 Pfam PF00437 Type II/IV secretion system protein 227 496 2.2E-74 T 12-10-2018 IPR001482 Type II/IV secretion system protein VAPA_1c21000 4cb3d28d7076d453f44782c9d11a61d7 630 Gene3D G3DSA:3.40.50.300 331 629 1.8E-108 T 12-10-2018 VAPA_1c21000 4cb3d28d7076d453f44782c9d11a61d7 630 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 424 438 - T 12-10-2018 IPR001482 Type II/IV secretion system protein VAPA_1c21000 4cb3d28d7076d453f44782c9d11a61d7 630 SUPERFAMILY SSF52540 216 625 3.81E-85 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c21000 4cb3d28d7076d453f44782c9d11a61d7 630 Gene3D G3DSA:3.30.450.90 199 330 1.6E-37 T 12-10-2018 VAPA_1c21000 4cb3d28d7076d453f44782c9d11a61d7 630 SUPERFAMILY SSF160246 21 164 2.09E-28 T 12-10-2018 IPR037257 General secretory system II, protein E, N-terminal superfamily VAPA_2c02270 7f4f33b5b6a917299162615bcc0c452d 529 Gene3D G3DSA:3.30.300.310 420 521 1.6E-29 T 12-10-2018 VAPA_2c02270 7f4f33b5b6a917299162615bcc0c452d 529 Gene3D G3DSA:3.40.50.12780 2 417 5.9E-110 T 12-10-2018 VAPA_2c02270 7f4f33b5b6a917299162615bcc0c452d 529 Pfam PF00501 AMP-binding enzyme 15 422 1.6E-93 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 VAPA_2c02270 7f4f33b5b6a917299162615bcc0c452d 529 SUPERFAMILY SSF56801 7 518 2.49E-139 T 12-10-2018 VAPA_2c02270 7f4f33b5b6a917299162615bcc0c452d 529 ProSitePatterns PS00455 Putative AMP-binding domain signature. 169 180 - T 12-10-2018 IPR020845 AMP-binding, conserved site VAPA_2c02270 7f4f33b5b6a917299162615bcc0c452d 529 Pfam PF13193 AMP-binding enzyme C-terminal domain 433 507 1.9E-16 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain VAPA_1c38010 b133f0278f61bdccf63e343f8b9f3f00 164 Pfam PF00376 MerR family regulatory protein 6 43 7.6E-16 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 VAPA_1c38010 b133f0278f61bdccf63e343f8b9f3f00 164 ProSitePatterns PS00552 MerR-type HTH domain signature. 8 30 - T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 VAPA_1c38010 b133f0278f61bdccf63e343f8b9f3f00 164 SUPERFAMILY SSF46955 5 117 5.49E-31 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily VAPA_1c38010 b133f0278f61bdccf63e343f8b9f3f00 164 Pfam PF09278 MerR, DNA binding 50 109 7.6E-10 T 12-10-2018 IPR015358 Transcription regulator MerR, DNA binding VAPA_1c38010 b133f0278f61bdccf63e343f8b9f3f00 164 SMART SM00422 5 74 4.5E-24 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 VAPA_1c38010 b133f0278f61bdccf63e343f8b9f3f00 164 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 6 17 3.0E-8 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 VAPA_1c38010 b133f0278f61bdccf63e343f8b9f3f00 164 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 17 30 3.0E-8 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 VAPA_1c38010 b133f0278f61bdccf63e343f8b9f3f00 164 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 41 61 3.0E-8 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 VAPA_1c38010 b133f0278f61bdccf63e343f8b9f3f00 164 Gene3D G3DSA:1.10.1660.10 4 143 1.0E-33 T 12-10-2018 VAPA_1c31740 adebb35ab461de7b5ad2173e7a8a83ae 179 Pfam PF07963 Prokaryotic N-terminal methylation motif 10 34 6.2E-6 T 12-10-2018 IPR012902 Prokaryotic N-terminal methylation site VAPA_1c31740 adebb35ab461de7b5ad2173e7a8a83ae 179 TIGRFAM TIGR02523 type_IV_pilV: type IV pilus modification protein PilV 12 147 8.8E-29 T 12-10-2018 IPR013362 Pilus modification type IV, PilV VAPA_1c46820 5a102e1b9297d67b9880ac9b31a985bb 375 Pfam PF05762 VWA domain containing CoxE-like protein 159 370 1.4E-51 T 12-10-2018 IPR008912 Uncharacterised protein family CoxE-like VAPA_1c46820 5a102e1b9297d67b9880ac9b31a985bb 375 Gene3D G3DSA:3.40.50.410 209 368 1.3E-11 T 12-10-2018 IPR036465 von Willebrand factor A-like domain superfamily VAPA_1c46820 5a102e1b9297d67b9880ac9b31a985bb 375 SUPERFAMILY SSF53300 210 359 2.7E-19 T 12-10-2018 IPR036465 von Willebrand factor A-like domain superfamily VAPA_1c46820 5a102e1b9297d67b9880ac9b31a985bb 375 SMART SM00327 212 371 1.6E-11 T 12-10-2018 IPR002035 von Willebrand factor, type A VAPA_1c17820 c1ba8c50b072b8ff33e5b5fc89cc0447 168 Pfam PF13671 AAA domain 7 128 9.8E-7 T 12-10-2018 VAPA_1c17820 c1ba8c50b072b8ff33e5b5fc89cc0447 168 TIGRFAM TIGR01313 therm_gnt_kin: carbohydrate kinase, thermoresistant glucokinase family 6 162 6.3E-47 T 12-10-2018 IPR006001 Carbohydrate kinase, thermoresistant glucokinase GO:0005975|GO:0016301 KEGG: 00030+2.7.1.12|MetaCyc: PWY-5530 VAPA_1c17820 c1ba8c50b072b8ff33e5b5fc89cc0447 168 Gene3D G3DSA:3.40.50.300 2 166 4.4E-51 T 12-10-2018 VAPA_1c17820 c1ba8c50b072b8ff33e5b5fc89cc0447 168 SUPERFAMILY SSF52540 3 165 3.66E-19 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c22660 7fa92d46d8bc746648d1c28215ab0104 486 Pfam PF00171 Aldehyde dehydrogenase family 16 472 1.2E-173 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 VAPA_1c22660 7fa92d46d8bc746648d1c28215ab0104 486 Gene3D G3DSA:3.40.309.10 246 442 1.2E-178 T 12-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 VAPA_1c22660 7fa92d46d8bc746648d1c28215ab0104 486 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 269 280 - T 12-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 VAPA_1c22660 7fa92d46d8bc746648d1c28215ab0104 486 TIGRFAM TIGR02299 HpaE: 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase 3 486 1.5E-244 T 12-10-2018 IPR011985 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase GO:0018480|GO:1901023 VAPA_1c22660 7fa92d46d8bc746648d1c28215ab0104 486 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 241 248 - T 12-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 VAPA_1c22660 7fa92d46d8bc746648d1c28215ab0104 486 Gene3D G3DSA:3.40.605.10 7 470 1.2E-178 T 12-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 VAPA_1c22660 7fa92d46d8bc746648d1c28215ab0104 486 SUPERFAMILY SSF53720 2 478 1.57E-165 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 VAPA_2c07170 3d4cb3292b8a05df3ebe3af0676dd3f0 289 SUPERFAMILY SSF53850 91 287 5.27E-31 T 12-10-2018 VAPA_2c07170 3d4cb3292b8a05df3ebe3af0676dd3f0 289 Gene3D G3DSA:1.10.10.10 1 87 3.0E-24 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_2c07170 3d4cb3292b8a05df3ebe3af0676dd3f0 289 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 9 66 1.1E-18 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_2c07170 3d4cb3292b8a05df3ebe3af0676dd3f0 289 Gene3D G3DSA:3.40.190.10 98 266 7.3E-49 T 12-10-2018 VAPA_2c07170 3d4cb3292b8a05df3ebe3af0676dd3f0 289 Gene3D G3DSA:3.40.190.10 163 259 7.3E-49 T 12-10-2018 VAPA_2c07170 3d4cb3292b8a05df3ebe3af0676dd3f0 289 SUPERFAMILY SSF46785 6 114 6.05E-24 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_2c07170 3d4cb3292b8a05df3ebe3af0676dd3f0 289 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 44 5.6E-5 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_2c07170 3d4cb3292b8a05df3ebe3af0676dd3f0 289 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 23 34 5.6E-5 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_2c07170 3d4cb3292b8a05df3ebe3af0676dd3f0 289 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 44 55 5.6E-5 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_2c07170 3d4cb3292b8a05df3ebe3af0676dd3f0 289 Pfam PF03466 LysR substrate binding domain 91 285 2.2E-30 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_1c15120 6f1d00383d1e165448b7f9b91426279e 380 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 9 126 2.1E-25 T 12-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 VAPA_1c15120 6f1d00383d1e165448b7f9b91426279e 380 ProSitePatterns PS01103 Aspartate-semialdehyde dehydrogenase signature. 272 286 - T 12-10-2018 IPR000319 Aspartate-semialdehyde dehydrogenase, conserved site GO:0004073|GO:0006520|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 VAPA_1c15120 6f1d00383d1e165448b7f9b91426279e 380 PIRSF PIRSF000148 6 380 1.2E-58 T 12-10-2018 VAPA_1c15120 6f1d00383d1e165448b7f9b91426279e 380 Hamap MF_02121 Aspartate-semialdehyde dehydrogenase [asd]. 6 378 31.637 T 12-10-2018 IPR012080 Aspartate-semialdehyde dehydrogenase GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 VAPA_1c15120 6f1d00383d1e165448b7f9b91426279e 380 TIGRFAM TIGR01745 asd_gamma: aspartate-semialdehyde dehydrogenase 9 378 1.2E-178 T 12-10-2018 IPR011534 Aspartate-semialdehyde dehydrogenase, gamma-type GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 VAPA_1c15120 6f1d00383d1e165448b7f9b91426279e 380 Gene3D G3DSA:3.30.360.10 140 361 1.2E-136 T 12-10-2018 VAPA_1c15120 6f1d00383d1e165448b7f9b91426279e 380 SUPERFAMILY SSF55347 139 365 6.0E-67 T 12-10-2018 VAPA_1c15120 6f1d00383d1e165448b7f9b91426279e 380 Gene3D G3DSA:3.40.50.720 9 367 1.2E-136 T 12-10-2018 VAPA_1c15120 6f1d00383d1e165448b7f9b91426279e 380 SUPERFAMILY SSF51735 9 152 7.18E-51 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c15120 6f1d00383d1e165448b7f9b91426279e 380 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 151 364 3.0E-51 T 12-10-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0005737|GO:0008652|GO:0016620|GO:0046983 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 VAPA_1c15120 6f1d00383d1e165448b7f9b91426279e 380 SMART SM00859 8 127 2.2E-26 T 12-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 VAPA_1c54620 ecb164e32c02f3621b0f955e9d30f37c 356 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 172 188 2.9E-27 T 12-10-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 VAPA_1c54620 ecb164e32c02f3621b0f955e9d30f37c 356 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 136 156 2.9E-27 T 12-10-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 VAPA_1c54620 ecb164e32c02f3621b0f955e9d30f37c 356 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 274 290 2.9E-27 T 12-10-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 VAPA_1c54620 ecb164e32c02f3621b0f955e9d30f37c 356 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 193 204 2.9E-27 T 12-10-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 VAPA_1c54620 ecb164e32c02f3621b0f955e9d30f37c 356 Gene3D G3DSA:1.10.390.10 186 354 2.2E-62 T 12-10-2018 IPR027268 Peptidase M4/M1, CTD superfamily VAPA_1c54620 ecb164e32c02f3621b0f955e9d30f37c 356 Pfam PF02868 Thermolysin metallopeptidase, alpha-helical domain 184 353 2.6E-47 T 12-10-2018 IPR001570 Peptidase M4, C-terminal GO:0004222 VAPA_1c54620 ecb164e32c02f3621b0f955e9d30f37c 356 SUPERFAMILY SSF55486 72 353 7.87E-76 T 12-10-2018 VAPA_1c54620 ecb164e32c02f3621b0f955e9d30f37c 356 Gene3D G3DSA:3.10.170.10 8 185 1.1E-62 T 12-10-2018 VAPA_1c54620 ecb164e32c02f3621b0f955e9d30f37c 356 Pfam PF01447 Thermolysin metallopeptidase, catalytic domain 82 180 9.3E-28 T 12-10-2018 IPR013856 Peptidase M4 domain GO:0004222 VAPA_2c12610 7f08f47937a13bb7ccf0bc85ab10dc53 250 SUPERFAMILY SSF53474 6 249 1.52E-26 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_2c12610 7f08f47937a13bb7ccf0bc85ab10dc53 250 Gene3D G3DSA:3.40.50.1820 1 250 4.5E-30 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_2c12610 7f08f47937a13bb7ccf0bc85ab10dc53 250 PRINTS PR00111 Alpha/beta hydrolase fold signature 38 53 1.3E-6 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 VAPA_2c12610 7f08f47937a13bb7ccf0bc85ab10dc53 250 PRINTS PR00111 Alpha/beta hydrolase fold signature 83 96 1.3E-6 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 VAPA_2c12610 7f08f47937a13bb7ccf0bc85ab10dc53 250 PRINTS PR00111 Alpha/beta hydrolase fold signature 201 215 1.3E-6 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 VAPA_2c12610 7f08f47937a13bb7ccf0bc85ab10dc53 250 Pfam PF12697 Alpha/beta hydrolase family 13 245 6.7E-14 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 VAPA_1c32800 263dd8c78b35824c74af4cc7401e553c 417 Pfam PF00589 Phage integrase family 244 393 6.3E-19 T 12-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 VAPA_1c32800 263dd8c78b35824c74af4cc7401e553c 417 SUPERFAMILY SSF56349 114 405 1.5E-47 T 12-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 VAPA_1c32800 263dd8c78b35824c74af4cc7401e553c 417 Pfam PF13356 Arm DNA-binding domain 10 101 3.3E-13 T 12-10-2018 IPR025166 Integrase, DNA-binding domain VAPA_1c32800 263dd8c78b35824c74af4cc7401e553c 417 Gene3D G3DSA:1.10.150.130 114 198 9.4E-22 T 12-10-2018 IPR010998 Integrase/recombinase, N-terminal VAPA_1c32800 263dd8c78b35824c74af4cc7401e553c 417 Gene3D G3DSA:1.10.443.10 235 408 6.6E-14 T 12-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 VAPA_1c32800 263dd8c78b35824c74af4cc7401e553c 417 Gene3D G3DSA:3.30.160.390 6 102 2.5E-6 T 12-10-2018 IPR038488 Integrase, DNA-binding domain superfamily VAPA_1c12780 888dc1a821cede3250113143cc3df139 328 ProSitePatterns PS00211 ABC transporters family signature. 155 169 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_1c12780 888dc1a821cede3250113143cc3df139 328 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 234 299 6.5E-17 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 VAPA_1c12780 888dc1a821cede3250113143cc3df139 328 SUPERFAMILY SSF52540 10 254 1.6E-72 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c12780 888dc1a821cede3250113143cc3df139 328 SMART SM00382 39 231 5.4E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c12780 888dc1a821cede3250113143cc3df139 328 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 232 318 7.4E-26 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 VAPA_1c12780 888dc1a821cede3250113143cc3df139 328 Gene3D G3DSA:3.40.50.300 8 325 1.2E-101 T 12-10-2018 VAPA_1c12780 888dc1a821cede3250113143cc3df139 328 Pfam PF00005 ABC transporter 31 182 1.7E-29 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c10760 7b8e18f93280edd10c9fa518e2c34a95 413 Gene3D G3DSA:3.40.50.970 3 409 1.2E-120 T 12-10-2018 VAPA_1c10760 7b8e18f93280edd10c9fa518e2c34a95 413 Pfam PF12573 2-oxoisovalerate dehydrogenase E1 alpha subunit N terminal 6 45 5.6E-20 T 12-10-2018 IPR022593 2-oxoisovalerate dehydrogenase, E1 alpha subunit, N-terminal domain KEGG: 00280+1.2.4.4|KEGG: 00640+1.2.4.4|MetaCyc: PWY-5046 VAPA_1c10760 7b8e18f93280edd10c9fa518e2c34a95 413 SUPERFAMILY SSF52518 6 408 5.26E-92 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold VAPA_1c10760 7b8e18f93280edd10c9fa518e2c34a95 413 Pfam PF00676 Dehydrogenase E1 component 82 375 1.5E-94 T 12-10-2018 IPR001017 Dehydrogenase, E1 component GO:0016624 Reactome: R-HSA-389661 VAPA_2c04580 18b39246364569be17fa3462f9de3685 147 SUPERFAMILY SSF47188 7 98 5.1E-11 T 12-10-2018 IPR035938 Hemerythrin-like superfamily VAPA_2c04580 18b39246364569be17fa3462f9de3685 147 Gene3D G3DSA:1.20.120.50 2 129 1.2E-7 T 12-10-2018 IPR035938 Hemerythrin-like superfamily VAPA_1c21850 ff64764238099549db1bf7ad8b08910e 226 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 36 214 5.6E-20 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 VAPA_1c21850 ff64764238099549db1bf7ad8b08910e 226 SUPERFAMILY SSF161098 13 201 5.49E-43 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c21850 ff64764238099549db1bf7ad8b08910e 226 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 14 110 1.0E-27 T 12-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 VAPA_1c21850 ff64764238099549db1bf7ad8b08910e 226 Gene3D G3DSA:1.10.3720.10 2 219 1.2E-52 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c55080 c36950ce8a614a8193898c1361efb1ba 153 SMART SM00100 19 136 3.7E-13 T 12-10-2018 IPR000595 Cyclic nucleotide-binding domain VAPA_1c55080 c36950ce8a614a8193898c1361efb1ba 153 Gene3D G3DSA:2.60.120.10 14 152 1.8E-23 T 12-10-2018 IPR014710 RmlC-like jelly roll fold VAPA_1c55080 c36950ce8a614a8193898c1361efb1ba 153 Pfam PF00027 Cyclic nucleotide-binding domain 43 120 1.6E-15 T 12-10-2018 IPR000595 Cyclic nucleotide-binding domain VAPA_1c55080 c36950ce8a614a8193898c1361efb1ba 153 SUPERFAMILY SSF51206 19 140 4.71E-21 T 12-10-2018 IPR018490 Cyclic nucleotide-binding-like VAPA_1c13440 3b87a1c4054cb87ea119de35bb188c7a 78 Gene3D G3DSA:2.30.30.320 10 78 3.9E-26 T 12-10-2018 IPR037135 DUF1653-like domain superfamily VAPA_1c13440 3b87a1c4054cb87ea119de35bb188c7a 78 Pfam PF07866 Protein of unknown function (DUF1653) 17 76 1.2E-25 T 12-10-2018 IPR023387 DUF1653-like domain VAPA_1c50080 a4475f9696b89585cb378b9d7131aee3 370 Pfam PF00296 Luciferase-like monooxygenase 1 321 2.6E-68 T 12-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 VAPA_1c50080 a4475f9696b89585cb378b9d7131aee3 370 Gene3D G3DSA:3.20.20.30 1 356 9.1E-80 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 VAPA_1c50080 a4475f9696b89585cb378b9d7131aee3 370 Hamap MF_01699 Pyrimidine monooxygenase RutA [rutA]. 1 360 68.866 T 12-10-2018 IPR019914 Pyrimidine monooxygenase RutA GO:0004497|GO:0006212|GO:0055114 KEGG: 00240+1.14.99.46 VAPA_1c50080 a4475f9696b89585cb378b9d7131aee3 370 TIGRFAM TIGR03612 RutA: pyrimidine utilization protein A 1 355 3.5E-214 T 12-10-2018 IPR019914 Pyrimidine monooxygenase RutA GO:0004497|GO:0006212|GO:0055114 KEGG: 00240+1.14.99.46 VAPA_1c50080 a4475f9696b89585cb378b9d7131aee3 370 SUPERFAMILY SSF51679 1 357 2.09E-77 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 VAPA_1c33750 cbbd3e050cff6d0580021bf129906980 126 SUPERFAMILY SSF54593 1 121 5.23E-24 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase VAPA_1c33750 cbbd3e050cff6d0580021bf129906980 126 Gene3D G3DSA:3.10.180.10 6 124 1.4E-36 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase VAPA_1c33750 cbbd3e050cff6d0580021bf129906980 126 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 5 121 5.1E-6 T 12-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain VAPA_2c02720 1ce195c91a85c34f1e48ba238c90d657 147 Gene3D G3DSA:3.10.450.50 2 137 9.0E-39 T 12-10-2018 VAPA_2c02720 1ce195c91a85c34f1e48ba238c90d657 147 Pfam PF07366 SnoaL-like polyketide cyclase 13 132 7.0E-32 T 12-10-2018 IPR009959 Polyketide cyclase SnoaL-like GO:0030638 MetaCyc: PWY-7352|MetaCyc: PWY-7354 VAPA_2c02720 1ce195c91a85c34f1e48ba238c90d657 147 SUPERFAMILY SSF54427 9 136 5.1E-34 T 12-10-2018 IPR032710 NTF2-like domain superfamily VAPA_1c50530 8b2a4a262ed8aada7898805a0ac460ed 466 Gene3D G3DSA:3.40.50.300 74 349 1.7E-113 T 12-10-2018 VAPA_1c50530 8b2a4a262ed8aada7898805a0ac460ed 466 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 128 347 2.4E-60 T 12-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 VAPA_1c50530 8b2a4a262ed8aada7898805a0ac460ed 466 SUPERFAMILY SSF52540 75 352 1.84E-85 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c50530 8b2a4a262ed8aada7898805a0ac460ed 466 Hamap MF_01347 ATP synthase subunit beta [atpB]. 1 465 56.509 T 12-10-2018 IPR005722 ATP synthase, F1 complex, beta subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201|Reactome: R-HSA-8949613 VAPA_1c50530 8b2a4a262ed8aada7898805a0ac460ed 466 Gene3D G3DSA:2.40.10.170 1 73 4.3E-29 T 12-10-2018 VAPA_1c50530 8b2a4a262ed8aada7898805a0ac460ed 466 SUPERFAMILY SSF47917 350 465 1.1E-53 T 12-10-2018 VAPA_1c50530 8b2a4a262ed8aada7898805a0ac460ed 466 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 6 71 4.8E-19 T 12-10-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 VAPA_1c50530 8b2a4a262ed8aada7898805a0ac460ed 466 SMART SM00382 140 332 0.0058 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c50530 8b2a4a262ed8aada7898805a0ac460ed 466 SUPERFAMILY SSF50615 2 73 1.62E-24 T 12-10-2018 IPR036121 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamily GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 VAPA_1c50530 8b2a4a262ed8aada7898805a0ac460ed 466 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 338 347 - T 12-10-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 VAPA_1c50530 8b2a4a262ed8aada7898805a0ac460ed 466 Gene3D G3DSA:1.10.1140.10 350 466 8.1E-58 T 12-10-2018 IPR024034 ATPase, F1/V1 complex, beta/alpha subunit, C-terminal KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 VAPA_1c50530 8b2a4a262ed8aada7898805a0ac460ed 466 TIGRFAM TIGR01039 atpD: ATP synthase F1, beta subunit 3 464 6.3E-247 T 12-10-2018 IPR005722 ATP synthase, F1 complex, beta subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201|Reactome: R-HSA-8949613 VAPA_1c46590 df96e99ee8e44ae0f33a3d8c4518a854 299 PIRSF PIRSF001553 1 293 3.1E-118 T 12-10-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 VAPA_1c46590 df96e99ee8e44ae0f33a3d8c4518a854 299 Gene3D G3DSA:3.40.50.720 2 126 1.9E-45 T 12-10-2018 VAPA_1c46590 df96e99ee8e44ae0f33a3d8c4518a854 299 SUPERFAMILY SSF51735 1 125 7.13E-39 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c46590 df96e99ee8e44ae0f33a3d8c4518a854 299 SMART SM00881 4 103 1.7E-31 T 12-10-2018 IPR003781 CoA-binding GO:0048037 VAPA_1c46590 df96e99ee8e44ae0f33a3d8c4518a854 299 ProSitePatterns PS01216 ATP-citrate lyase / succinyl-CoA ligases family signature 1. 155 184 - T 12-10-2018 IPR033847 ATP-citrate lyase/succinyl-CoA ligase, conserved site VAPA_1c46590 df96e99ee8e44ae0f33a3d8c4518a854 299 PRINTS PR01798 Succinyl-CoA synthase signature 180 198 2.9E-36 T 12-10-2018 VAPA_1c46590 df96e99ee8e44ae0f33a3d8c4518a854 299 PRINTS PR01798 Succinyl-CoA synthase signature 243 260 2.9E-36 T 12-10-2018 VAPA_1c46590 df96e99ee8e44ae0f33a3d8c4518a854 299 PRINTS PR01798 Succinyl-CoA synthase signature 85 102 2.9E-36 T 12-10-2018 VAPA_1c46590 df96e99ee8e44ae0f33a3d8c4518a854 299 PRINTS PR01798 Succinyl-CoA synthase signature 211 224 2.9E-36 T 12-10-2018 VAPA_1c46590 df96e99ee8e44ae0f33a3d8c4518a854 299 SUPERFAMILY SSF52210 126 290 1.7E-53 T 12-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 VAPA_1c46590 df96e99ee8e44ae0f33a3d8c4518a854 299 Hamap MF_01988 Succinate--CoA ligase [ADP-forming] subunit alpha [sucD]. 1 291 40.593 T 12-10-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 VAPA_1c46590 df96e99ee8e44ae0f33a3d8c4518a854 299 Gene3D G3DSA:3.40.50.261 127 291 7.8E-69 T 12-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 VAPA_1c46590 df96e99ee8e44ae0f33a3d8c4518a854 299 ProSitePatterns PS00399 ATP-citrate lyase / succinyl-CoA ligases family active site. 239 252 - T 12-10-2018 IPR017440 ATP-citrate lyase/succinyl-CoA ligase, active site VAPA_1c46590 df96e99ee8e44ae0f33a3d8c4518a854 299 TIGRFAM TIGR01019 sucCoAalpha: succinate-CoA ligase, alpha subunit 3 290 2.5E-128 T 12-10-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 VAPA_1c46590 df96e99ee8e44ae0f33a3d8c4518a854 299 Pfam PF00549 CoA-ligase 154 265 3.5E-15 T 12-10-2018 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 VAPA_1c46590 df96e99ee8e44ae0f33a3d8c4518a854 299 Pfam PF02629 CoA binding domain 6 102 9.1E-26 T 12-10-2018 IPR003781 CoA-binding GO:0048037 VAPA_1c42910 1e833ca0b43ee41cea187e672a0391d2 283 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 96 278 2.8E-19 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 VAPA_1c42910 1e833ca0b43ee41cea187e672a0391d2 283 SUPERFAMILY SSF161098 5 279 1.03E-58 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c42910 1e833ca0b43ee41cea187e672a0391d2 283 Gene3D G3DSA:1.10.3720.10 2 276 1.4E-53 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c09270 5463d66257faec4ec001472cc1f9bc89 306 TIGRFAM TIGR01139 cysK: cysteine synthase A 7 301 3.0E-119 T 12-10-2018 IPR005859 Cysteine synthase CysK GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 VAPA_1c09270 5463d66257faec4ec001472cc1f9bc89 306 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 7 287 6.2E-66 T 12-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme VAPA_1c09270 5463d66257faec4ec001472cc1f9bc89 306 Gene3D G3DSA:3.40.50.1100 44 145 8.7E-111 T 12-10-2018 VAPA_1c09270 5463d66257faec4ec001472cc1f9bc89 306 SUPERFAMILY SSF53686 3 300 2.23E-91 T 12-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme VAPA_1c09270 5463d66257faec4ec001472cc1f9bc89 306 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 32 50 - T 12-10-2018 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 VAPA_1c09270 5463d66257faec4ec001472cc1f9bc89 306 Gene3D G3DSA:3.40.50.1100 8 298 8.7E-111 T 12-10-2018 VAPA_1c09270 5463d66257faec4ec001472cc1f9bc89 306 TIGRFAM TIGR01136 cysKM: cysteine synthase 7 302 6.2E-116 T 12-10-2018 IPR005856 Cysteine synthase GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 VAPA_1c38910 bea8a1ddee52ba37a2ae1e0ae8cd154c 291 Pfam PF05036 Sporulation related domain 216 288 6.9E-18 T 12-10-2018 IPR007730 Sporulation-like domain GO:0042834 VAPA_1c38910 bea8a1ddee52ba37a2ae1e0ae8cd154c 291 SUPERFAMILY SSF110997 215 289 1.29E-17 T 12-10-2018 IPR036680 Sporulation-like domain superfamily GO:0042834 VAPA_1c38910 bea8a1ddee52ba37a2ae1e0ae8cd154c 291 Gene3D G3DSA:3.30.70.1070 217 290 8.3E-13 T 12-10-2018 IPR036680 Sporulation-like domain superfamily GO:0042834 VAPA_1c46250 b8b47c9c9cf841769a56e66bc093198d 310 SMART SM00028 133 166 2.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 VAPA_1c46250 b8b47c9c9cf841769a56e66bc093198d 310 SMART SM00028 167 200 12.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 VAPA_1c46250 b8b47c9c9cf841769a56e66bc093198d 310 Gene3D G3DSA:1.25.40.10 68 258 1.2E-14 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 VAPA_1c46250 b8b47c9c9cf841769a56e66bc093198d 310 SUPERFAMILY SSF48452 103 224 8.26E-16 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 VAPA_1c51080 c4c99cc91a52d30d5830b9514f7f5b24 336 Pfam PF00490 Delta-aminolevulinic acid dehydratase 13 331 4.6E-138 T 12-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 VAPA_1c51080 c4c99cc91a52d30d5830b9514f7f5b24 336 SMART SM01004 9 333 4.9E-232 T 12-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 VAPA_1c51080 c4c99cc91a52d30d5830b9514f7f5b24 336 ProSitePatterns PS00169 Delta-aminolevulinic acid dehydratase active site. 252 264 - T 12-10-2018 IPR030656 Delta-aminolevulinic acid dehydratase, active site KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 VAPA_1c51080 c4c99cc91a52d30d5830b9514f7f5b24 336 Gene3D G3DSA:3.20.20.70 2 336 4.2E-144 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 VAPA_1c51080 c4c99cc91a52d30d5830b9514f7f5b24 336 SUPERFAMILY SSF51569 6 335 9.52E-142 T 12-10-2018 VAPA_1c51080 c4c99cc91a52d30d5830b9514f7f5b24 336 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 252 268 4.5E-58 T 12-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 VAPA_1c51080 c4c99cc91a52d30d5830b9514f7f5b24 336 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 129 143 4.5E-58 T 12-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 VAPA_1c51080 c4c99cc91a52d30d5830b9514f7f5b24 336 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 198 217 4.5E-58 T 12-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 VAPA_1c51080 c4c99cc91a52d30d5830b9514f7f5b24 336 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 307 326 4.5E-58 T 12-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 VAPA_1c51080 c4c99cc91a52d30d5830b9514f7f5b24 336 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 277 292 4.5E-58 T 12-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 VAPA_1c51080 c4c99cc91a52d30d5830b9514f7f5b24 336 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 160 179 4.5E-58 T 12-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 VAPA_1c51080 c4c99cc91a52d30d5830b9514f7f5b24 336 PIRSF PIRSF001415 2 336 1.7E-145 T 12-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 VAPA_1c19450 112bfa265fc683b50c837b61d28d1b3f 116 Gene3D G3DSA:3.40.30.10 1 116 5.9E-45 T 12-10-2018 VAPA_1c19450 112bfa265fc683b50c837b61d28d1b3f 116 TIGRFAM TIGR00014 arsC: arsenate reductase (glutaredoxin) 1 113 8.7E-39 T 12-10-2018 IPR006659 Arsenate reductase GO:0008794|GO:0055114 MetaCyc: PWY-4202|MetaCyc: PWY-4621 VAPA_1c19450 112bfa265fc683b50c837b61d28d1b3f 116 SUPERFAMILY SSF52833 1 114 2.45E-33 T 12-10-2018 IPR036249 Thioredoxin-like superfamily VAPA_1c19450 112bfa265fc683b50c837b61d28d1b3f 116 Pfam PF03960 ArsC family 6 112 1.9E-15 T 12-10-2018 IPR006660 Arsenate reductase-like VAPA_1c37900 8c306c69be7145f4fc356cb4acb029d5 321 SUPERFAMILY SSF117396 5 291 4.45E-77 T 12-10-2018 IPR036520 UPF0759 superfamily VAPA_1c37900 8c306c69be7145f4fc356cb4acb029d5 321 Gene3D G3DSA:3.20.20.410 143 292 9.0E-24 T 12-10-2018 IPR036520 UPF0759 superfamily VAPA_1c37900 8c306c69be7145f4fc356cb4acb029d5 321 Gene3D G3DSA:3.20.20.410 1 142 8.6E-38 T 12-10-2018 IPR036520 UPF0759 superfamily VAPA_1c37900 8c306c69be7145f4fc356cb4acb029d5 321 Pfam PF01904 Protein of unknown function DUF72 22 288 1.5E-66 T 12-10-2018 IPR002763 Protein of unknown function DUF72 VAPA_2c09380 21aa976e6a201ca4d90a2d7be2d85a06 314 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 5.9E-17 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_2c09380 21aa976e6a201ca4d90a2d7be2d85a06 314 SUPERFAMILY SSF46785 4 84 3.14E-20 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_2c09380 21aa976e6a201ca4d90a2d7be2d85a06 314 Pfam PF03466 LysR substrate binding domain 88 295 3.9E-43 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_2c09380 21aa976e6a201ca4d90a2d7be2d85a06 314 Gene3D G3DSA:3.40.190.10 91 293 1.7E-62 T 12-10-2018 VAPA_2c09380 21aa976e6a201ca4d90a2d7be2d85a06 314 Gene3D G3DSA:1.10.10.10 3 87 5.3E-26 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_2c09380 21aa976e6a201ca4d90a2d7be2d85a06 314 Gene3D G3DSA:3.40.190.10 164 266 1.7E-62 T 12-10-2018 VAPA_2c09380 21aa976e6a201ca4d90a2d7be2d85a06 314 SUPERFAMILY SSF53850 89 298 1.21E-46 T 12-10-2018 VAPA_1c34690 e28b78ab46fa38f8059e034ecd2adbc5 249 ProSitePatterns PS01065 Electron transfer flavoprotein beta-subunit signature. 155 175 - T 12-10-2018 IPR000049 Electron transfer flavoprotein, beta-subunit, conserved site GO:0009055 Reactome: R-HSA-611105|Reactome: R-HSA-8876725 VAPA_1c34690 e28b78ab46fa38f8059e034ecd2adbc5 249 SUPERFAMILY SSF52402 1 242 1.47E-87 T 12-10-2018 VAPA_1c34690 e28b78ab46fa38f8059e034ecd2adbc5 249 SMART SM00893 23 211 2.9E-68 T 12-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 VAPA_1c34690 e28b78ab46fa38f8059e034ecd2adbc5 249 Pfam PF01012 Electron transfer flavoprotein domain 28 206 1.4E-46 T 12-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 VAPA_1c34690 e28b78ab46fa38f8059e034ecd2adbc5 249 PIRSF PIRSF000090 1 249 4.6E-86 T 12-10-2018 IPR012255 Electron transfer flavoprotein, beta subunit GO:0009055 Reactome: R-HSA-611105|Reactome: R-HSA-8876725 VAPA_1c34690 e28b78ab46fa38f8059e034ecd2adbc5 249 Gene3D G3DSA:3.40.50.620 1 247 2.6E-88 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold VAPA_1c23150 ab93b209ea19959f21225503159ad563 172 Hamap MF_00682 Co-chaperone protein HscB [hscB]. 5 171 20.759 T 12-10-2018 IPR004640 Co-chaperone Hsc20 GO:0001671|GO:0051087|GO:0097428 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 VAPA_1c23150 ab93b209ea19959f21225503159ad563 172 Gene3D G3DSA:1.10.287.110 6 82 1.8E-19 T 12-10-2018 IPR036869 Chaperone J-domain superfamily VAPA_1c23150 ab93b209ea19959f21225503159ad563 172 TIGRFAM TIGR00714 hscB: Fe-S protein assembly co-chaperone HscB 19 166 1.4E-28 T 12-10-2018 IPR004640 Co-chaperone Hsc20 GO:0001671|GO:0051087|GO:0097428 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 VAPA_1c23150 ab93b209ea19959f21225503159ad563 172 Gene3D G3DSA:1.20.1280.20 83 171 2.9E-21 T 12-10-2018 IPR036386 HscB, C-terminal domain superfamily GO:0051259 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 VAPA_1c23150 ab93b209ea19959f21225503159ad563 172 Pfam PF07743 HSCB C-terminal oligomerisation domain 91 163 4.6E-19 T 12-10-2018 IPR009073 Co-chaperone HscB, C-terminal oligomerisation domain GO:0051259 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 VAPA_1c23150 ab93b209ea19959f21225503159ad563 172 SUPERFAMILY SSF46565 8 77 4.58E-15 T 12-10-2018 IPR036869 Chaperone J-domain superfamily VAPA_1c23150 ab93b209ea19959f21225503159ad563 172 SUPERFAMILY SSF47144 84 170 2.09E-20 T 12-10-2018 IPR036386 HscB, C-terminal domain superfamily GO:0051259 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 VAPA_1c25780 a7b32e319acc92b7de7e2408bed4d41a 283 Gene3D G3DSA:1.10.3720.10 71 268 1.4E-24 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c25780 a7b32e319acc92b7de7e2408bed4d41a 283 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 101 268 4.2E-25 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 VAPA_1c25780 a7b32e319acc92b7de7e2408bed4d41a 283 SUPERFAMILY SSF161098 77 260 2.22E-32 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c25350 50b156ab3e5cb90c339f1fc3dd47b5f9 269 Pfam PF05690 Thiazole biosynthesis protein ThiG 9 258 1.9E-102 T 12-10-2018 IPR033983 Thiazole synthase ThiG KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 VAPA_1c25350 50b156ab3e5cb90c339f1fc3dd47b5f9 269 Hamap MF_00443 Thiazole synthase [thiG]. 6 264 39.917 T 12-10-2018 IPR008867 Thiazole synthase GO:0009228 KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 VAPA_1c25350 50b156ab3e5cb90c339f1fc3dd47b5f9 269 SUPERFAMILY SSF110399 5 248 6.67E-79 T 12-10-2018 VAPA_1c25350 50b156ab3e5cb90c339f1fc3dd47b5f9 269 Gene3D G3DSA:3.20.20.70 1 263 4.9E-100 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 VAPA_1c05040 bfae9964c44a4f9561a387119c8f9d4a 362 Pfam PF14840 Processivity clamp loader gamma complex DNA pol III C-term 222 346 1.2E-6 T 12-10-2018 IPR032780 DNA polymerase III subunit delta, C-terminal KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 VAPA_1c05040 bfae9964c44a4f9561a387119c8f9d4a 362 Gene3D G3DSA:3.40.50.300 1 142 1.5E-46 T 12-10-2018 VAPA_1c05040 bfae9964c44a4f9561a387119c8f9d4a 362 Pfam PF06144 DNA polymerase III, delta subunit 20 197 9.7E-19 T 12-10-2018 IPR010372 DNA polymerase III delta, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0009360 VAPA_1c05040 bfae9964c44a4f9561a387119c8f9d4a 362 SUPERFAMILY SSF48019 219 348 1.24E-25 T 12-10-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 VAPA_1c05040 bfae9964c44a4f9561a387119c8f9d4a 362 TIGRFAM TIGR01128 holA: DNA polymerase III, delta subunit 16 344 9.4E-71 T 12-10-2018 IPR005790 DNA polymerase III, delta subunit GO:0003677|GO:0006260 VAPA_1c05040 bfae9964c44a4f9561a387119c8f9d4a 362 Gene3D G3DSA:1.20.272.10 221 351 8.8E-24 T 12-10-2018 VAPA_1c05040 bfae9964c44a4f9561a387119c8f9d4a 362 Gene3D G3DSA:1.10.8.60 145 219 1.1E-24 T 12-10-2018 VAPA_1c05040 bfae9964c44a4f9561a387119c8f9d4a 362 SUPERFAMILY SSF52540 3 217 2.87E-40 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c35180 486fe198a518b96fdc9d278e45db6a7e 343 Gene3D G3DSA:3.40.190.10 122 219 1.3E-65 T 12-10-2018 VAPA_1c35180 486fe198a518b96fdc9d278e45db6a7e 343 Pfam PF09084 NMT1/THI5 like 51 257 7.9E-47 T 12-10-2018 IPR015168 SsuA/THI5-like VAPA_1c35180 486fe198a518b96fdc9d278e45db6a7e 343 Gene3D G3DSA:3.40.190.10 42 307 1.3E-65 T 12-10-2018 VAPA_1c35180 486fe198a518b96fdc9d278e45db6a7e 343 SUPERFAMILY SSF53850 42 318 1.81E-27 T 12-10-2018 VAPA_2c08440 e2c1e3795fc3c1168094910fa44ade5a 322 Gene3D G3DSA:3.90.180.10 12 316 6.7E-93 T 12-10-2018 VAPA_2c08440 e2c1e3795fc3c1168094910fa44ade5a 322 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 87 2.2E-9 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 VAPA_2c08440 e2c1e3795fc3c1168094910fa44ade5a 322 SUPERFAMILY SSF50129 1 143 2.2E-33 T 12-10-2018 IPR011032 GroES-like superfamily VAPA_2c08440 e2c1e3795fc3c1168094910fa44ade5a 322 SUPERFAMILY SSF51735 112 288 5.5E-34 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_2c08440 e2c1e3795fc3c1168094910fa44ade5a 322 SMART SM00829 10 320 6.9E-23 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 VAPA_2c08440 e2c1e3795fc3c1168094910fa44ade5a 322 Gene3D G3DSA:3.40.50.720 123 266 6.7E-93 T 12-10-2018 VAPA_2c08440 e2c1e3795fc3c1168094910fa44ade5a 322 Pfam PF13602 Zinc-binding dehydrogenase 184 320 8.9E-22 T 12-10-2018 VAPA_1c07630 aa8ba6f02537845ae56883fd2f0a2109 738 Pfam PF00702 haloacid dehalogenase-like hydrolase 416 633 3.2E-40 T 12-10-2018 VAPA_1c07630 aa8ba6f02537845ae56883fd2f0a2109 738 Gene3D G3DSA:3.40.1110.10 431 551 1.5E-86 T 12-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 VAPA_1c07630 aa8ba6f02537845ae56883fd2f0a2109 738 Pfam PF00122 E1-E2 ATPase 218 399 1.3E-52 T 12-10-2018 VAPA_1c07630 aa8ba6f02537845ae56883fd2f0a2109 738 Gene3D G3DSA:3.40.50.1000 401 671 1.5E-86 T 12-10-2018 IPR023214 HAD superfamily VAPA_1c07630 aa8ba6f02537845ae56883fd2f0a2109 738 PRINTS PR00943 Copper-transporting ATPase signature 130 149 1.6E-13 T 12-10-2018 VAPA_1c07630 aa8ba6f02537845ae56883fd2f0a2109 738 PRINTS PR00943 Copper-transporting ATPase signature 187 206 1.6E-13 T 12-10-2018 VAPA_1c07630 aa8ba6f02537845ae56883fd2f0a2109 738 PRINTS PR00943 Copper-transporting ATPase signature 207 225 1.6E-13 T 12-10-2018 VAPA_1c07630 aa8ba6f02537845ae56883fd2f0a2109 738 PRINTS PR00943 Copper-transporting ATPase signature 403 418 1.6E-13 T 12-10-2018 VAPA_1c07630 aa8ba6f02537845ae56883fd2f0a2109 738 PRINTS PR00943 Copper-transporting ATPase signature 596 613 1.6E-13 T 12-10-2018 VAPA_1c07630 aa8ba6f02537845ae56883fd2f0a2109 738 PRINTS PR00943 Copper-transporting ATPase signature 341 355 1.6E-13 T 12-10-2018 VAPA_1c07630 aa8ba6f02537845ae56883fd2f0a2109 738 Gene3D G3DSA:2.70.150.20 211 323 6.1E-41 T 12-10-2018 VAPA_1c07630 aa8ba6f02537845ae56883fd2f0a2109 738 SUPERFAMILY SSF56784 418 726 2.64E-54 T 12-10-2018 IPR036412 HAD-like superfamily VAPA_1c07630 aa8ba6f02537845ae56883fd2f0a2109 738 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 126 729 7.3E-174 T 12-10-2018 VAPA_1c07630 aa8ba6f02537845ae56883fd2f0a2109 738 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 422 428 - T 12-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 VAPA_1c07630 aa8ba6f02537845ae56883fd2f0a2109 738 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 145 728 3.2E-183 T 12-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 VAPA_1c07630 aa8ba6f02537845ae56883fd2f0a2109 738 SUPERFAMILY SSF81665 186 414 1.22E-13 T 12-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 VAPA_1c07630 aa8ba6f02537845ae56883fd2f0a2109 738 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 619 638 4.7E-29 T 12-10-2018 VAPA_1c07630 aa8ba6f02537845ae56883fd2f0a2109 738 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 566 576 4.7E-29 T 12-10-2018 VAPA_1c07630 aa8ba6f02537845ae56883fd2f0a2109 738 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 268 282 4.7E-29 T 12-10-2018 VAPA_1c07630 aa8ba6f02537845ae56883fd2f0a2109 738 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 420 434 4.7E-29 T 12-10-2018 VAPA_1c07630 aa8ba6f02537845ae56883fd2f0a2109 738 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 544 555 4.7E-29 T 12-10-2018 VAPA_1c07630 aa8ba6f02537845ae56883fd2f0a2109 738 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 642 654 4.7E-29 T 12-10-2018 VAPA_1c07630 aa8ba6f02537845ae56883fd2f0a2109 738 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 189 698 1.7E-87 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 VAPA_1c07630 aa8ba6f02537845ae56883fd2f0a2109 738 SUPERFAMILY SSF81653 222 318 1.03E-24 T 12-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 VAPA_1c14380 7d4cd8e2dc70030d95b751e35846e006 82 Pfam PF11730 Protein of unknown function (DUF3297) 11 81 1.2E-37 T 12-10-2018 IPR021724 Protein of unknown function DUF3297 VAPA_1c10990 f26650bef53cc004a634a325af2dace5 519 Pfam PF00005 ABC transporter 285 440 6.0E-18 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c10990 f26650bef53cc004a634a325af2dace5 519 SMART SM00382 293 489 0.0053 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c10990 f26650bef53cc004a634a325af2dace5 519 SMART SM00382 34 224 5.3E-9 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c10990 f26650bef53cc004a634a325af2dace5 519 ProSitePatterns PS00211 ABC transporters family signature. 413 427 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_1c10990 f26650bef53cc004a634a325af2dace5 519 SUPERFAMILY SSF52540 9 230 9.43E-53 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c10990 f26650bef53cc004a634a325af2dace5 519 Gene3D G3DSA:3.40.50.300 249 513 2.7E-41 T 12-10-2018 VAPA_1c10990 f26650bef53cc004a634a325af2dace5 519 Gene3D G3DSA:3.40.50.300 4 235 1.6E-53 T 12-10-2018 VAPA_1c10990 f26650bef53cc004a634a325af2dace5 519 SUPERFAMILY SSF52540 252 499 1.78E-43 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c10990 f26650bef53cc004a634a325af2dace5 519 Pfam PF00005 ABC transporter 25 176 2.2E-26 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c48580 afdd4baecb488bc67d748389b772fefa 371 Gene3D G3DSA:3.40.50.2300 145 364 1.4E-104 T 12-10-2018 VAPA_1c48580 afdd4baecb488bc67d748389b772fefa 371 Pfam PF13458 Periplasmic binding protein 25 359 3.5E-59 T 12-10-2018 IPR028081 Leucine-binding protein domain VAPA_1c48580 afdd4baecb488bc67d748389b772fefa 371 Gene3D G3DSA:3.40.50.2300 26 360 1.4E-104 T 12-10-2018 VAPA_1c48580 afdd4baecb488bc67d748389b772fefa 371 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 254 272 6.1E-7 T 12-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 VAPA_1c48580 afdd4baecb488bc67d748389b772fefa 371 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 26 42 6.1E-7 T 12-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 VAPA_1c48580 afdd4baecb488bc67d748389b772fefa 371 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 48 64 6.1E-7 T 12-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 VAPA_1c48580 afdd4baecb488bc67d748389b772fefa 371 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 67 85 6.1E-7 T 12-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 VAPA_1c48580 afdd4baecb488bc67d748389b772fefa 371 SUPERFAMILY SSF53822 26 370 1.02E-70 T 12-10-2018 IPR028082 Periplasmic binding protein-like I VAPA_1c03700 b1855509fc181cd6e942afb2fd3094e9 101 SUPERFAMILY SSF54292 21 98 5.49E-16 T 12-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 VAPA_1c03700 b1855509fc181cd6e942afb2fd3094e9 101 Gene3D G3DSA:3.10.20.440 6 98 1.5E-6 T 12-10-2018 VAPA_1c03700 b1855509fc181cd6e942afb2fd3094e9 101 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 19 96 2.1E-20 T 12-10-2018 VAPA_1c42200 11f3043104054dbc088f7f9f461ae3ac 263 Gene3D G3DSA:3.40.50.300 16 235 2.5E-56 T 12-10-2018 VAPA_1c42200 11f3043104054dbc088f7f9f461ae3ac 263 Pfam PF00005 ABC transporter 30 168 2.8E-31 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c42200 11f3043104054dbc088f7f9f461ae3ac 263 SUPERFAMILY SSF52540 27 225 9.03E-61 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c42200 11f3043104054dbc088f7f9f461ae3ac 263 SMART SM00382 26 216 3.1E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c42200 11f3043104054dbc088f7f9f461ae3ac 263 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_1c42570 6521e0ddc0f44271762d2714a12f08ec 138 SUPERFAMILY SSF52821 23 137 3.01E-32 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily VAPA_1c42570 6521e0ddc0f44271762d2714a12f08ec 138 Pfam PF00581 Rhodanese-like domain 42 130 7.1E-16 T 12-10-2018 IPR001763 Rhodanese-like domain VAPA_1c42570 6521e0ddc0f44271762d2714a12f08ec 138 Gene3D G3DSA:3.40.250.10 43 138 4.9E-27 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily VAPA_1c42570 6521e0ddc0f44271762d2714a12f08ec 138 SMART SM00450 36 134 9.1E-21 T 12-10-2018 IPR001763 Rhodanese-like domain VAPA_1c54510 eb4e81b641d75d3e9db6a4009c633389 222 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 14 112 5.4E-25 T 12-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 VAPA_1c54510 eb4e81b641d75d3e9db6a4009c633389 222 SUPERFAMILY SSF161098 14 203 8.11E-43 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c54510 eb4e81b641d75d3e9db6a4009c633389 222 Gene3D G3DSA:1.10.3720.10 3 219 3.8E-53 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c54510 eb4e81b641d75d3e9db6a4009c633389 222 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 36 216 6.8E-20 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 VAPA_2c06070 01bb2648b921897a302da89fd2d90094 58 Gene3D G3DSA:1.10.8.60 10 54 5.5E-6 T 12-10-2018 VAPA_2c06070 01bb2648b921897a302da89fd2d90094 58 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 20 53 2.4E-6 T 12-10-2018 IPR019489 Clp ATPase, C-terminal VAPA_1c15140 a70c07021f13246aadff56310e057674 216 Gene3D G3DSA:3.20.19.10 1 184 1.7E-76 T 12-10-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel KEGG: 00290+4.2.1.33 VAPA_1c15140 a70c07021f13246aadff56310e057674 216 Hamap MF_01031 3-isopropylmalate dehydratase small subunit [leuD]. 1 210 43.428 T 12-10-2018 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 VAPA_1c15140 a70c07021f13246aadff56310e057674 216 TIGRFAM TIGR00171 leuD: 3-isopropylmalate dehydratase, small subunit 1 196 3.0E-82 T 12-10-2018 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 VAPA_1c15140 a70c07021f13246aadff56310e057674 216 Pfam PF00694 Aconitase C-terminal domain 1 132 2.3E-38 T 12-10-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain KEGG: 00290+4.2.1.33 VAPA_1c15140 a70c07021f13246aadff56310e057674 216 SUPERFAMILY SSF52016 1 201 2.55E-61 T 12-10-2018 VAPA_2c12600 90fba189eecb4ed9a31d91fe57e8854c 117 Gene3D G3DSA:3.30.1330.40 1 117 2.5E-33 T 12-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 VAPA_2c12600 90fba189eecb4ed9a31d91fe57e8854c 117 SUPERFAMILY SSF55298 4 116 5.18E-24 T 12-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 VAPA_2c12600 90fba189eecb4ed9a31d91fe57e8854c 117 Pfam PF01042 Endoribonuclease L-PSP 6 116 1.4E-17 T 12-10-2018 IPR006175 YjgF/YER057c/UK114 family Reactome: R-HSA-8849175 VAPA_1c42520 c3147e70b5274043daa10c47a11dba64 374 SUPERFAMILY SSF142754 44 354 3.92E-106 T 12-10-2018 IPR036094 Quinolinate synthetase A superfamily GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 VAPA_1c42520 c3147e70b5274043daa10c47a11dba64 374 Gene3D G3DSA:3.40.50.10800 215 310 3.1E-92 T 12-10-2018 VAPA_1c42520 c3147e70b5274043daa10c47a11dba64 374 Gene3D G3DSA:3.40.50.10800 130 352 3.1E-92 T 12-10-2018 VAPA_1c42520 c3147e70b5274043daa10c47a11dba64 374 TIGRFAM TIGR00550 nadA: quinolinate synthetase complex, A subunit 43 355 9.2E-106 T 12-10-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 VAPA_1c42520 c3147e70b5274043daa10c47a11dba64 374 Pfam PF02445 Quinolinate synthetase A protein 46 353 1.1E-100 T 12-10-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 VAPA_1c42520 c3147e70b5274043daa10c47a11dba64 374 Gene3D G3DSA:3.40.50.10800 46 335 3.1E-92 T 12-10-2018 VAPA_1c33670 7b9564f03722318cf0e6c19a981dc70c 297 Gene3D G3DSA:1.10.10.10 2 86 1.5E-18 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c33670 7b9564f03722318cf0e6c19a981dc70c 297 SUPERFAMILY SSF46785 1 110 4.09E-19 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c33670 7b9564f03722318cf0e6c19a981dc70c 297 Pfam PF03466 LysR substrate binding domain 87 286 1.5E-34 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_1c33670 7b9564f03722318cf0e6c19a981dc70c 297 SUPERFAMILY SSF53850 88 288 2.71E-39 T 12-10-2018 VAPA_1c33670 7b9564f03722318cf0e6c19a981dc70c 297 Gene3D G3DSA:3.40.190.290 90 286 2.4E-36 T 12-10-2018 VAPA_1c33670 7b9564f03722318cf0e6c19a981dc70c 297 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 2.3E-16 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c07570 5abebaa2745f9967feb2ac5ec562b930 128 Gene3D G3DSA:2.170.150.40 12 121 6.7E-35 T 12-10-2018 VAPA_1c07570 5abebaa2745f9967feb2ac5ec562b930 128 Pfam PF04248 Domain of unknown function (DUF427) 25 116 6.2E-31 T 12-10-2018 IPR007361 Domain of unknown function DUF427 VAPA_2c08070 d9e469a31a6c9bb9ab953f158889e139 486 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 280 291 - T 12-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 VAPA_2c08070 d9e469a31a6c9bb9ab953f158889e139 486 SUPERFAMILY SSF53720 7 485 1.83E-155 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 VAPA_2c08070 d9e469a31a6c9bb9ab953f158889e139 486 Gene3D G3DSA:3.40.605.10 23 481 1.3E-163 T 12-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 VAPA_2c08070 d9e469a31a6c9bb9ab953f158889e139 486 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 252 259 - T 12-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 VAPA_2c08070 d9e469a31a6c9bb9ab953f158889e139 486 Pfam PF00171 Aldehyde dehydrogenase family 17 482 2.8E-167 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 VAPA_2c08070 d9e469a31a6c9bb9ab953f158889e139 486 Gene3D G3DSA:3.40.309.10 256 453 1.3E-163 T 12-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 VAPA_1c20850 bb7545cac277be0bd3259c4e4fdd51af 507 Gene3D G3DSA:3.90.1210.30 6 83 1.6E-21 T 12-10-2018 VAPA_1c20850 bb7545cac277be0bd3259c4e4fdd51af 507 Pfam PF08666 SAF domain 13 81 3.8E-14 T 12-10-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 VAPA_1c20850 bb7545cac277be0bd3259c4e4fdd51af 507 SMART SM00858 13 82 2.3E-17 T 12-10-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 VAPA_1c20850 bb7545cac277be0bd3259c4e4fdd51af 507 Pfam PF04295 D-galactarate dehydratase / Altronate hydrolase, C terminus 109 505 5.8E-154 T 12-10-2018 IPR007392 D-galactarate/Altronate dehydratase, C-terminal GO:0016829 VAPA_1c08560 011237de1abe8efc1ab23881a97da4a3 253 SMART SM00382 30 214 3.5E-8 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c08560 011237de1abe8efc1ab23881a97da4a3 253 SUPERFAMILY SSF52540 5 237 5.33E-58 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c08560 011237de1abe8efc1ab23881a97da4a3 253 Gene3D G3DSA:3.40.50.300 1 239 1.1E-57 T 12-10-2018 VAPA_1c08560 011237de1abe8efc1ab23881a97da4a3 253 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 215 237 4.3E-9 T 12-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal VAPA_1c08560 011237de1abe8efc1ab23881a97da4a3 253 Pfam PF00005 ABC transporter 22 165 1.7E-25 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_2c05150 0659a8eb3b481ae172044f40d526af7a 767 Gene3D G3DSA:3.40.228.10 148 594 4.3E-179 T 12-10-2018 VAPA_2c05150 0659a8eb3b481ae172044f40d526af7a 767 Gene3D G3DSA:3.90.55.10 51 561 4.3E-179 T 12-10-2018 VAPA_2c05150 0659a8eb3b481ae172044f40d526af7a 767 Gene3D G3DSA:3.40.50.740 55 520 4.3E-179 T 12-10-2018 VAPA_2c05150 0659a8eb3b481ae172044f40d526af7a 767 ProSitePatterns PS00932 Prokaryotic molybdopterin oxidoreductases signature 3. 663 690 - T 12-10-2018 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 VAPA_2c05150 0659a8eb3b481ae172044f40d526af7a 767 Pfam PF00384 Molybdopterin oxidoreductase 55 511 9.7E-59 T 12-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VAPA_2c05150 0659a8eb3b481ae172044f40d526af7a 767 Pfam PF01568 Molydopterin dinucleotide binding domain 624 739 1.0E-21 T 12-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 VAPA_2c05150 0659a8eb3b481ae172044f40d526af7a 767 SUPERFAMILY SSF50692 613 764 1.42E-36 T 12-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily VAPA_2c05150 0659a8eb3b481ae172044f40d526af7a 767 Gene3D G3DSA:2.40.40.20 602 761 2.1E-38 T 12-10-2018 VAPA_2c05150 0659a8eb3b481ae172044f40d526af7a 767 SUPERFAMILY SSF53706 13 626 3.53E-146 T 12-10-2018 VAPA_1c28840 3a56d3352915dc2aa3d7c6d329bc337c 471 Pfam PF07958 Protein of unknown function (DUF1688) 49 471 4.7E-141 T 12-10-2018 IPR012469 Protein of unknown function DUF1688 VAPA_1c36370 326f577f946bdc636c88386d8323fec8 828 Gene3D G3DSA:3.50.50.60 8 291 2.5E-83 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c36370 326f577f946bdc636c88386d8323fec8 828 Gene3D G3DSA:3.30.413.10 642 792 6.3E-35 T 12-10-2018 VAPA_1c36370 326f577f946bdc636c88386d8323fec8 828 TIGRFAM TIGR02374 nitri_red_nirB: nitrite reductase [NAD(P)H], large subunit 7 804 6.7E-275 T 12-10-2018 IPR012744 Nitrite reductase [NAD(P)H] large subunit, NirB GO:0008942|GO:0042128|GO:0050660|GO:0050661|GO:0055114 VAPA_1c36370 326f577f946bdc636c88386d8323fec8 828 ProSitePatterns PS00365 Nitrite and sulfite reductases iron-sulfur/siroheme-binding site. 689 705 - T 12-10-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 VAPA_1c36370 326f577f946bdc636c88386d8323fec8 828 Gene3D G3DSA:1.10.10.1100 432 484 1.1E-9 T 12-10-2018 VAPA_1c36370 326f577f946bdc636c88386d8323fec8 828 Gene3D G3DSA:3.30.390.30 328 407 4.5E-6 T 12-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 VAPA_1c36370 326f577f946bdc636c88386d8323fec8 828 Pfam PF04324 BFD-like [2Fe-2S] binding domain 433 480 9.0E-14 T 12-10-2018 IPR007419 BFD-like [2Fe-2S]-binding domain VAPA_1c36370 326f577f946bdc636c88386d8323fec8 828 Pfam PF04324 BFD-like [2Fe-2S] binding domain 497 547 1.0E-13 T 12-10-2018 IPR007419 BFD-like [2Fe-2S]-binding domain VAPA_1c36370 326f577f946bdc636c88386d8323fec8 828 SUPERFAMILY SSF51905 147 321 2.04E-27 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c36370 326f577f946bdc636c88386d8323fec8 828 Gene3D G3DSA:3.50.50.60 115 255 2.5E-83 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c36370 326f577f946bdc636c88386d8323fec8 828 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 243 259 1.3E-17 T 12-10-2018 VAPA_1c36370 326f577f946bdc636c88386d8323fec8 828 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 152 170 1.3E-17 T 12-10-2018 VAPA_1c36370 326f577f946bdc636c88386d8323fec8 828 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 107 125 1.3E-17 T 12-10-2018 VAPA_1c36370 326f577f946bdc636c88386d8323fec8 828 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 1.3E-17 T 12-10-2018 VAPA_1c36370 326f577f946bdc636c88386d8323fec8 828 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 269 291 1.3E-17 T 12-10-2018 VAPA_1c36370 326f577f946bdc636c88386d8323fec8 828 SUPERFAMILY SSF51905 1 196 2.87E-40 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c36370 326f577f946bdc636c88386d8323fec8 828 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 292 5.1E-50 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 VAPA_1c36370 326f577f946bdc636c88386d8323fec8 828 PRINTS PR00397 Sirohaem Fe-binding site signature 646 664 8.5E-8 T 12-10-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 VAPA_1c36370 326f577f946bdc636c88386d8323fec8 828 PRINTS PR00397 Sirohaem Fe-binding site signature 689 707 8.5E-8 T 12-10-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 VAPA_1c36370 326f577f946bdc636c88386d8323fec8 828 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 244 258 4.9E-12 T 12-10-2018 VAPA_1c36370 326f577f946bdc636c88386d8323fec8 828 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 4.9E-12 T 12-10-2018 VAPA_1c36370 326f577f946bdc636c88386d8323fec8 828 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 152 177 4.9E-12 T 12-10-2018 VAPA_1c36370 326f577f946bdc636c88386d8323fec8 828 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 284 291 4.9E-12 T 12-10-2018 VAPA_1c36370 326f577f946bdc636c88386d8323fec8 828 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 572 633 4.1E-14 T 12-10-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 VAPA_1c36370 326f577f946bdc636c88386d8323fec8 828 SUPERFAMILY SSF55124 532 651 2.62E-23 T 12-10-2018 IPR036136 Nitrite/Sulfite reductase ferredoxin-like domain superfamily GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 VAPA_1c36370 326f577f946bdc636c88386d8323fec8 828 PIRSF PIRSF037149 1 828 0.0 T 12-10-2018 IPR017121 Nitrite reductase [NAD(P)H], large subunit GO:0042128 VAPA_1c36370 326f577f946bdc636c88386d8323fec8 828 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 643 782 1.1E-25 T 12-10-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 VAPA_1c36370 326f577f946bdc636c88386d8323fec8 828 SUPERFAMILY SSF56014 643 804 1.83E-50 T 12-10-2018 VAPA_2c12200 cc76ee48bede6845461308154d287b45 291 Gene3D G3DSA:3.30.450.40 17 176 2.9E-5 T 12-10-2018 IPR029016 GAF-like domain superfamily VAPA_2c12200 cc76ee48bede6845461308154d287b45 291 Gene3D G3DSA:1.10.10.10 193 258 1.8E-15 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_2c12200 cc76ee48bede6845461308154d287b45 291 Pfam PF00196 Bacterial regulatory proteins, luxR family 199 252 3.7E-13 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_2c12200 cc76ee48bede6845461308154d287b45 291 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 200 214 2.5E-7 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_2c12200 cc76ee48bede6845461308154d287b45 291 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 214 230 2.5E-7 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_2c12200 cc76ee48bede6845461308154d287b45 291 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 230 242 2.5E-7 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_2c12200 cc76ee48bede6845461308154d287b45 291 SMART SM00421 197 254 7.8E-15 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_2c12200 cc76ee48bede6845461308154d287b45 291 SUPERFAMILY SSF46894 189 254 1.7E-15 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 VAPA_1c04770 8074b9e1cb1d953590dc048765c74685 544 Gene3D G3DSA:3.90.76.10 58 217 5.6E-170 T 12-10-2018 VAPA_1c04770 8074b9e1cb1d953590dc048765c74685 544 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 79 460 1.2E-101 T 12-10-2018 IPR000914 Solute-binding protein family 5 domain VAPA_1c04770 8074b9e1cb1d953590dc048765c74685 544 SUPERFAMILY SSF53850 36 543 2.49E-146 T 12-10-2018 VAPA_1c04770 8074b9e1cb1d953590dc048765c74685 544 Gene3D G3DSA:3.40.190.10 218 532 5.6E-170 T 12-10-2018 VAPA_1c04770 8074b9e1cb1d953590dc048765c74685 544 PIRSF PIRSF002741 26 544 1.2E-111 T 12-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 VAPA_1c04770 8074b9e1cb1d953590dc048765c74685 544 Gene3D G3DSA:3.10.105.10 299 519 5.6E-170 T 12-10-2018 VAPA_1c53950 e16900addb1e2d52410c906a25b8d18e 759 SUPERFAMILY SSF55073 492 675 3.3E-58 T 12-10-2018 IPR029787 Nucleotide cyclase VAPA_1c53950 e16900addb1e2d52410c906a25b8d18e 759 Pfam PF00211 Adenylate and Guanylate cyclase catalytic domain 492 672 1.0E-36 T 12-10-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 VAPA_1c53950 e16900addb1e2d52410c906a25b8d18e 759 Gene3D G3DSA:3.30.70.1230 486 685 4.9E-63 T 12-10-2018 IPR029787 Nucleotide cyclase VAPA_1c53950 e16900addb1e2d52410c906a25b8d18e 759 SMART SM01080 34 399 9.4E-74 T 12-10-2018 IPR007890 CHASE2 VAPA_1c53950 e16900addb1e2d52410c906a25b8d18e 759 Pfam PF05226 CHASE2 domain 27 393 7.9E-54 T 12-10-2018 IPR007890 CHASE2 VAPA_1c53950 e16900addb1e2d52410c906a25b8d18e 759 SMART SM00044 459 656 3.6E-13 T 12-10-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 VAPA_1c45340 de1524333db708fa5be975459cee9570 230 PIRSF PIRSF000709 8 166 2.5E-7 T 12-10-2018 VAPA_1c45340 de1524333db708fa5be975459cee9570 230 SUPERFAMILY SSF53254 10 216 3.8E-55 T 12-10-2018 IPR029033 Histidine phosphatase superfamily VAPA_1c45340 de1524333db708fa5be975459cee9570 230 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 12 194 1.9E-57 T 12-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 VAPA_1c45340 de1524333db708fa5be975459cee9570 230 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 14 23 - T 12-10-2018 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824 VAPA_1c45340 de1524333db708fa5be975459cee9570 230 Gene3D G3DSA:3.40.50.1240 10 218 9.1E-57 T 12-10-2018 IPR029033 Histidine phosphatase superfamily VAPA_1c45340 de1524333db708fa5be975459cee9570 230 SMART SM00855 11 165 3.4E-24 T 12-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 VAPA_1c05960 1a9813eeb2f39c06d878d4e1b044f40b 634 Gene3D G3DSA:1.10.510.10 169 343 3.1E-50 T 12-10-2018 VAPA_1c05960 1a9813eeb2f39c06d878d4e1b044f40b 634 SMART SM00219 68 343 9.4E-6 T 12-10-2018 IPR020635 Tyrosine-protein kinase, catalytic domain GO:0004713|GO:0006468 VAPA_1c05960 1a9813eeb2f39c06d878d4e1b044f40b 634 SUPERFAMILY SSF56112 66 359 8.77E-50 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily VAPA_1c05960 1a9813eeb2f39c06d878d4e1b044f40b 634 Pfam PF14326 Domain of unknown function (DUF4384) 496 571 1.9E-15 T 12-10-2018 IPR025493 Domain of unknown function DUF4384 VAPA_1c05960 1a9813eeb2f39c06d878d4e1b044f40b 634 Gene3D G3DSA:3.30.200.20 51 168 3.1E-50 T 12-10-2018 VAPA_1c05960 1a9813eeb2f39c06d878d4e1b044f40b 634 ProSitePatterns PS00109 Tyrosine protein kinases specific active-site signature. 206 218 - T 12-10-2018 IPR008266 Tyrosine-protein kinase, active site GO:0004672|GO:0006468 VAPA_1c05960 1a9813eeb2f39c06d878d4e1b044f40b 634 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 74 97 - T 12-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 VAPA_1c05960 1a9813eeb2f39c06d878d4e1b044f40b 634 Pfam PF00069 Protein kinase domain 68 290 3.7E-27 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 VAPA_1c25610 90d8b00d8705278d934c6466cc45c48f 152 SUPERFAMILY SSF55729 8 147 3.54E-24 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase VAPA_1c25610 90d8b00d8705278d934c6466cc45c48f 152 Pfam PF00583 Acetyltransferase (GNAT) family 45 127 3.6E-10 T 12-10-2018 IPR000182 GNAT domain VAPA_1c25610 90d8b00d8705278d934c6466cc45c48f 152 Gene3D G3DSA:3.40.630.30 1 149 8.1E-39 T 12-10-2018 VAPA_1c16640 7dd45f89acd151a5acb5588c3cb8d807 88 Hamap MF_00337 Exodeoxyribonuclease 7 small subunit [xseB]. 24 84 13.446 T 12-10-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 VAPA_1c16640 7dd45f89acd151a5acb5588c3cb8d807 88 SUPERFAMILY SSF116842 22 86 3.53E-18 T 12-10-2018 VAPA_1c16640 7dd45f89acd151a5acb5588c3cb8d807 88 Gene3D G3DSA:1.10.287.1040 19 88 3.1E-22 T 12-10-2018 IPR037004 Exonuclease VII, small subunit superfamily GO:0006308|GO:0008855|GO:0009318 VAPA_1c16640 7dd45f89acd151a5acb5588c3cb8d807 88 PIRSF PIRSF006488 8 88 5.8E-20 T 12-10-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 VAPA_1c16640 7dd45f89acd151a5acb5588c3cb8d807 88 ProDom PD028235 EXONUCLEASE SMALL SUBUNIT VII EXODEOXYRIBONUCLEASE HYDROLASE NUCLEASE PROBABLE VII SIMILAR 41 65 1.0E-4 T 12-10-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 VAPA_1c16640 7dd45f89acd151a5acb5588c3cb8d807 88 Pfam PF02609 Exonuclease VII small subunit 25 75 9.7E-19 T 12-10-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 VAPA_1c16640 7dd45f89acd151a5acb5588c3cb8d807 88 TIGRFAM TIGR01280 xseB: exodeoxyribonuclease VII, small subunit 24 78 1.1E-20 T 12-10-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 VAPA_1c17940 8bb37a5647e410da7b9818537eb984d7 225 Pfam PF00355 Rieske [2Fe-2S] domain 8 92 1.2E-16 T 12-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 VAPA_1c17940 8bb37a5647e410da7b9818537eb984d7 225 Gene3D G3DSA:2.102.10.10 6 136 1.5E-30 T 12-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 VAPA_1c17940 8bb37a5647e410da7b9818537eb984d7 225 SUPERFAMILY SSF50022 6 124 1.83E-31 T 12-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 VAPA_1c15250 b07e5d94bed1d9fe529ee9e293677ec0 328 Pfam PF00056 lactate/malate dehydrogenase, NAD binding domain 6 155 1.5E-35 T 12-10-2018 IPR001236 Lactate/malate dehydrogenase, N-terminal GO:0016491|GO:0055114 VAPA_1c15250 b07e5d94bed1d9fe529ee9e293677ec0 328 PIRSF PIRSF000102 2 326 9.5E-64 T 12-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 VAPA_1c15250 b07e5d94bed1d9fe529ee9e293677ec0 328 TIGRFAM TIGR01759 MalateDH-SF1: malate dehydrogenase 3 322 2.3E-143 T 12-10-2018 IPR010945 Malate dehydrogenase, type 2 GO:0006108|GO:0016615|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383 VAPA_1c15250 b07e5d94bed1d9fe529ee9e293677ec0 328 Hamap MF_01517 Malate dehydrogenase [mdh]. 2 328 55.449 T 12-10-2018 IPR010945 Malate dehydrogenase, type 2 GO:0006108|GO:0016615|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383 VAPA_1c15250 b07e5d94bed1d9fe529ee9e293677ec0 328 Gene3D G3DSA:3.40.50.720 1 157 6.0E-58 T 12-10-2018 VAPA_1c15250 b07e5d94bed1d9fe529ee9e293677ec0 328 SUPERFAMILY SSF56327 160 327 1.54E-57 T 12-10-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 VAPA_1c15250 b07e5d94bed1d9fe529ee9e293677ec0 328 SUPERFAMILY SSF51735 4 158 1.66E-45 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c15250 b07e5d94bed1d9fe529ee9e293677ec0 328 Gene3D G3DSA:3.90.110.10 158 328 3.2E-60 T 12-10-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 VAPA_1c15250 b07e5d94bed1d9fe529ee9e293677ec0 328 Pfam PF02866 lactate/malate dehydrogenase, alpha/beta C-terminal domain 160 320 1.4E-33 T 12-10-2018 IPR022383 Lactate/malate dehydrogenase, C-terminal GO:0016616|GO:0055114 VAPA_2c04100 2baa15625f79eb04b5adaf6a458d88e8 217 Pfam PF04972 BON domain 152 216 2.2E-10 T 12-10-2018 IPR007055 BON domain VAPA_2c04100 2baa15625f79eb04b5adaf6a458d88e8 217 Pfam PF04972 BON domain 78 142 3.0E-17 T 12-10-2018 IPR007055 BON domain VAPA_2c04100 2baa15625f79eb04b5adaf6a458d88e8 217 Pfam PF04972 BON domain 3 70 1.5E-15 T 12-10-2018 IPR007055 BON domain VAPA_2c04100 2baa15625f79eb04b5adaf6a458d88e8 217 SMART SM00749 8 71 0.0092 T 12-10-2018 IPR014004 Transport-associated and nodulation domain, bacteria VAPA_2c04100 2baa15625f79eb04b5adaf6a458d88e8 217 SMART SM00749 83 146 1.3 T 12-10-2018 IPR014004 Transport-associated and nodulation domain, bacteria VAPA_2c04100 2baa15625f79eb04b5adaf6a458d88e8 217 SMART SM00749 154 217 0.19 T 12-10-2018 IPR014004 Transport-associated and nodulation domain, bacteria VAPA_1c43370 d6e86d94d3108a94cea0cf59648e9a15 264 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 84 103 1.0E-25 T 12-10-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 VAPA_1c43370 d6e86d94d3108a94cea0cf59648e9a15 264 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 184 206 1.0E-25 T 12-10-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 VAPA_1c43370 d6e86d94d3108a94cea0cf59648e9a15 264 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 25 46 1.0E-25 T 12-10-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 VAPA_1c43370 d6e86d94d3108a94cea0cf59648e9a15 264 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 206 225 1.0E-25 T 12-10-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 VAPA_1c43370 d6e86d94d3108a94cea0cf59648e9a15 264 TIGRFAM TIGR01400 fliR: flagellar biosynthetic protein FliR 17 255 3.7E-65 T 12-10-2018 IPR006303 Flagellar biosynthesis protein FliR GO:0016021|GO:0044780 VAPA_1c43370 d6e86d94d3108a94cea0cf59648e9a15 264 Pfam PF01311 Bacterial export proteins, family 1 17 248 2.9E-63 T 12-10-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 VAPA_1c14850 6cf46e630b7bbb34686958028a3a6ad1 79 ProSitePatterns PS00012 Phosphopantetheine attachment site. 32 47 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site VAPA_1c14850 6cf46e630b7bbb34686958028a3a6ad1 79 Hamap MF_01217 Acyl carrier protein [acpP]. 3 77 22.355 T 12-10-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 VAPA_1c14850 6cf46e630b7bbb34686958028a3a6ad1 79 Pfam PF00550 Phosphopantetheine attachment site 7 72 7.1E-17 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain VAPA_1c14850 6cf46e630b7bbb34686958028a3a6ad1 79 ProDom PD000887 CARRIER ACYL PHOSPHOPANTETHEINE ACP ACID FATTY BIOSYNTHESIS LIPID SYNTHESIS CHLOROPLAST 41 72 4.0E-11 T 12-10-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 VAPA_1c14850 6cf46e630b7bbb34686958028a3a6ad1 79 Gene3D G3DSA:1.10.1200.10 1 79 2.7E-30 T 12-10-2018 IPR036736 ACP-like superfamily VAPA_1c14850 6cf46e630b7bbb34686958028a3a6ad1 79 TIGRFAM TIGR00517 acyl_carrier: acyl carrier protein 1 77 3.6E-35 T 12-10-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 VAPA_1c14850 6cf46e630b7bbb34686958028a3a6ad1 79 SUPERFAMILY SSF47336 1 76 3.93E-24 T 12-10-2018 IPR036736 ACP-like superfamily VAPA_1c14850 6cf46e630b7bbb34686958028a3a6ad1 79 SMART SM00823 Phosphopantetheine attachment site 5 63 0.003 T 12-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 VAPA_1c47700 e98120a2a04306df0072e19342c5bdf5 466 Gene3D G3DSA:3.90.1300.10 1 463 2.1E-120 T 12-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 VAPA_1c47700 e98120a2a04306df0072e19342c5bdf5 466 SUPERFAMILY SSF75304 2 455 2.49E-120 T 12-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 VAPA_1c47700 e98120a2a04306df0072e19342c5bdf5 466 Pfam PF01425 Amidase 24 447 5.8E-92 T 12-10-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 VAPA_1c47700 e98120a2a04306df0072e19342c5bdf5 466 ProSitePatterns PS00571 Amidases signature. 152 183 - T 12-10-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 VAPA_1c20210 ad0050cc7c950b39e5bdf642d3a0f084 551 Gene3D G3DSA:3.30.300.310 436 539 3.6E-28 T 12-10-2018 VAPA_1c20210 ad0050cc7c950b39e5bdf642d3a0f084 551 SUPERFAMILY SSF56801 11 537 5.76E-128 T 12-10-2018 VAPA_1c20210 ad0050cc7c950b39e5bdf642d3a0f084 551 ProSitePatterns PS00455 Putative AMP-binding domain signature. 183 194 - T 12-10-2018 IPR020845 AMP-binding, conserved site VAPA_1c20210 ad0050cc7c950b39e5bdf642d3a0f084 551 Pfam PF13193 AMP-binding enzyme C-terminal domain 450 524 4.8E-14 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain VAPA_1c20210 ad0050cc7c950b39e5bdf642d3a0f084 551 Pfam PF00501 AMP-binding enzyme 19 440 9.0E-85 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 VAPA_1c20210 ad0050cc7c950b39e5bdf642d3a0f084 551 Gene3D G3DSA:3.40.50.12780 1 435 4.4E-122 T 12-10-2018 VAPA_2c09950 9846c45dc42ce9007cf0bba216eab483 315 Pfam PF00561 alpha/beta hydrolase fold 63 300 3.3E-21 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 VAPA_2c09950 9846c45dc42ce9007cf0bba216eab483 315 SUPERFAMILY SSF53474 40 314 1.87E-62 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_2c09950 9846c45dc42ce9007cf0bba216eab483 315 PRINTS PR00412 Epoxide hydrolase signature 132 145 2.1E-6 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 VAPA_2c09950 9846c45dc42ce9007cf0bba216eab483 315 PRINTS PR00412 Epoxide hydrolase signature 291 313 2.1E-6 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 VAPA_2c09950 9846c45dc42ce9007cf0bba216eab483 315 PRINTS PR00412 Epoxide hydrolase signature 69 87 2.1E-6 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 VAPA_2c09950 9846c45dc42ce9007cf0bba216eab483 315 Gene3D G3DSA:3.40.50.1820 41 315 5.2E-84 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_2c09950 9846c45dc42ce9007cf0bba216eab483 315 PRINTS PR00111 Alpha/beta hydrolase fold signature 146 159 1.8E-5 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 VAPA_2c09950 9846c45dc42ce9007cf0bba216eab483 315 PRINTS PR00111 Alpha/beta hydrolase fold signature 132 145 1.8E-5 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 VAPA_2c09950 9846c45dc42ce9007cf0bba216eab483 315 PRINTS PR00111 Alpha/beta hydrolase fold signature 88 103 1.8E-5 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 VAPA_1c13840 6c017af8f5dc51b681f939bae7d7ac31 453 SUPERFAMILY SSF103378 6 446 8.76E-115 T 12-10-2018 IPR036148 MmgE/PrpD superfamily GO:0016829 VAPA_1c13840 6c017af8f5dc51b681f939bae7d7ac31 453 Gene3D G3DSA:3.30.1330.120 271 402 1.7E-100 T 12-10-2018 VAPA_1c13840 6c017af8f5dc51b681f939bae7d7ac31 453 Pfam PF03972 MmgE/PrpD family 9 442 1.2E-129 T 12-10-2018 IPR005656 MmgE/PrpD GO:0016829 VAPA_1c13840 6c017af8f5dc51b681f939bae7d7ac31 453 Gene3D G3DSA:1.10.4100.10 28 418 1.7E-100 T 12-10-2018 VAPA_2c01390 0b482670f18d84780938adef934a79a7 409 SUPERFAMILY SSF54966 2 121 5.76E-35 T 12-10-2018 IPR036422 RuBisCO large subunit, N-terminal domain superfamily GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 VAPA_2c01390 0b482670f18d84780938adef934a79a7 409 Pfam PF00016 Ribulose bisphosphate carboxylase large chain, catalytic domain 129 409 2.0E-81 T 12-10-2018 IPR000685 Ribulose bisphosphate carboxylase, large subunit, C-terminal GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 VAPA_2c01390 0b482670f18d84780938adef934a79a7 409 ProSitePatterns PS00157 Ribulose bisphosphate carboxylase large chain active site. 171 179 - T 12-10-2018 IPR020878 Ribulose bisphosphate carboxylase, large chain, active site GO:0000287|GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 VAPA_2c01390 0b482670f18d84780938adef934a79a7 409 Gene3D G3DSA:3.20.20.110 125 409 3.5E-97 T 12-10-2018 IPR036376 Ribulose bisphosphate carboxylase, large subunit, C-terminal domain superfamily GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 VAPA_2c01390 0b482670f18d84780938adef934a79a7 409 SUPERFAMILY SSF51649 124 409 2.36E-92 T 12-10-2018 IPR036376 Ribulose bisphosphate carboxylase, large subunit, C-terminal domain superfamily GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 VAPA_2c01390 0b482670f18d84780938adef934a79a7 409 Pfam PF02788 Ribulose bisphosphate carboxylase large chain, N-terminal domain 9 119 8.1E-10 T 12-10-2018 IPR017443 Ribulose bisphosphate carboxylase, large subunit, ferrodoxin-like N-terminal GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 VAPA_2c01390 0b482670f18d84780938adef934a79a7 409 Gene3D G3DSA:3.30.70.150 1 122 3.2E-37 T 12-10-2018 IPR036422 RuBisCO large subunit, N-terminal domain superfamily GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 VAPA_1c29830 4d9aec09d9b7d394376c937319be63f4 298 SUPERFAMILY SSF51735 9 273 4.58E-49 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c29830 4d9aec09d9b7d394376c937319be63f4 298 Gene3D G3DSA:3.40.50.720 9 283 7.8E-55 T 12-10-2018 VAPA_1c29830 4d9aec09d9b7d394376c937319be63f4 298 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 71 264 2.4E-26 T 12-10-2018 VAPA_1c29830 4d9aec09d9b7d394376c937319be63f4 298 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 109 120 3.9E-11 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c29830 4d9aec09d9b7d394376c937319be63f4 298 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 210 227 3.9E-11 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c29830 4d9aec09d9b7d394376c937319be63f4 298 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 18 35 3.9E-11 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c29830 4d9aec09d9b7d394376c937319be63f4 298 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 189 208 3.9E-11 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c29830 4d9aec09d9b7d394376c937319be63f4 298 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 243 263 3.9E-11 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c19120 7dbdcb9031b3e6aa33b618944fa589fb 593 Gene3D G3DSA:3.40.50.300 377 591 1.7E-64 T 12-10-2018 VAPA_1c19120 7dbdcb9031b3e6aa33b618944fa589fb 593 Gene3D G3DSA:3.40.50.1010 125 284 2.3E-23 T 12-10-2018 VAPA_1c19120 7dbdcb9031b3e6aa33b618944fa589fb 593 SUPERFAMILY SSF88723 127 281 2.55E-9 T 12-10-2018 IPR029060 PIN-like domain superfamily VAPA_1c19120 7dbdcb9031b3e6aa33b618944fa589fb 593 Pfam PF13638 PIN domain 129 282 2.5E-34 T 12-10-2018 IPR002716 PIN domain VAPA_1c19120 7dbdcb9031b3e6aa33b618944fa589fb 593 Pfam PF02562 PhoH-like protein 379 582 9.4E-53 T 12-10-2018 IPR003714 PhoH-like protein GO:0005524 VAPA_1c19120 7dbdcb9031b3e6aa33b618944fa589fb 593 SMART SM00670 127 269 1.2E-6 T 12-10-2018 IPR002716 PIN domain VAPA_1c19120 7dbdcb9031b3e6aa33b618944fa589fb 593 SUPERFAMILY SSF52540 378 568 4.37E-29 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c35410 d5d81047dea6c8967a5d310f497fe57c 258 SUPERFAMILY SSF56281 3 231 1.83E-38 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like VAPA_1c35410 d5d81047dea6c8967a5d310f497fe57c 258 Gene3D G3DSA:3.60.15.10 5 244 2.4E-36 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like VAPA_1c35410 d5d81047dea6c8967a5d310f497fe57c 258 Pfam PF12706 Beta-lactamase superfamily domain 28 208 9.8E-21 T 12-10-2018 IPR001279 Metallo-beta-lactamase VAPA_1c35410 d5d81047dea6c8967a5d310f497fe57c 258 SMART SM00849 12 218 1.3E-6 T 12-10-2018 IPR001279 Metallo-beta-lactamase VAPA_1c15780 83dade4ee2fbaba6fef0276426d84203 334 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 200 299 3.2E-23 T 12-10-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 VAPA_1c15780 83dade4ee2fbaba6fef0276426d84203 334 Gene3D G3DSA:3.40.50.720 1 202 1.4E-49 T 12-10-2018 VAPA_1c15780 83dade4ee2fbaba6fef0276426d84203 334 Gene3D G3DSA:1.10.1040.10 203 321 1.4E-31 T 12-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 VAPA_1c15780 83dade4ee2fbaba6fef0276426d84203 334 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 11 196 1.8E-46 T 12-10-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 VAPA_1c15780 83dade4ee2fbaba6fef0276426d84203 334 PIRSF PIRSF000105 4 325 8.1E-75 T 12-10-2018 IPR022694 3-hydroxyacyl-CoA dehydrogenase GO:0003857|GO:0006631|GO:0055114|GO:0070403 VAPA_1c15780 83dade4ee2fbaba6fef0276426d84203 334 SUPERFAMILY SSF48179 199 311 6.72E-27 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 VAPA_1c15780 83dade4ee2fbaba6fef0276426d84203 334 SUPERFAMILY SSF51735 9 197 9.17E-40 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c41550 e385bb57e08a40b72c33dbbb02fc2e22 320 Gene3D G3DSA:3.40.50.1360 51 311 5.1E-68 T 12-10-2018 VAPA_1c41550 e385bb57e08a40b72c33dbbb02fc2e22 320 Gene3D G3DSA:1.10.10.10 1 50 2.4E-21 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c41550 e385bb57e08a40b72c33dbbb02fc2e22 320 SUPERFAMILY SSF100950 60 310 2.85E-62 T 12-10-2018 IPR037171 NagB/RpiA transferase-like VAPA_1c41550 e385bb57e08a40b72c33dbbb02fc2e22 320 Pfam PF04198 Putative sugar-binding domain 57 310 9.5E-61 T 12-10-2018 IPR007324 Sugar-binding domain, putative GO:0030246 VAPA_1c11810 702c26a0500d55a09fc8a381fa1d0847 434 Pfam PF01266 FAD dependent oxidoreductase 36 390 1.1E-55 T 12-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 VAPA_1c11810 702c26a0500d55a09fc8a381fa1d0847 434 Gene3D G3DSA:3.30.9.10 129 353 3.4E-75 T 12-10-2018 VAPA_1c11810 702c26a0500d55a09fc8a381fa1d0847 434 Gene3D G3DSA:3.50.50.60 36 392 3.4E-75 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c11810 702c26a0500d55a09fc8a381fa1d0847 434 SUPERFAMILY SSF51905 35 419 9.58E-49 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c05070 4e117e1791fd24976acd9f389ebfe55a 639 Hamap MF_01522 Low affinity potassium transport system protein kup [kup]. 21 639 33.735 T 12-10-2018 IPR023051 Potassium uptake protein, low affinity, Kup VAPA_1c05070 4e117e1791fd24976acd9f389ebfe55a 639 Pfam PF02705 K+ potassium transporter 30 560 2.9E-211 T 12-10-2018 IPR003855 Potassium transporter GO:0015079|GO:0016020|GO:0071805 VAPA_1c13320 bfe43a772c8cd7a9bbe03af6dad43776 339 SUPERFAMILY SSF53850 32 331 5.44E-63 T 12-10-2018 VAPA_1c13320 bfe43a772c8cd7a9bbe03af6dad43776 339 Pfam PF13343 Bacterial extracellular solute-binding protein 79 319 7.4E-50 T 12-10-2018 VAPA_1c13320 bfe43a772c8cd7a9bbe03af6dad43776 339 Gene3D G3DSA:3.40.190.10 47 298 4.2E-58 T 12-10-2018 VAPA_1c13320 bfe43a772c8cd7a9bbe03af6dad43776 339 Gene3D G3DSA:3.40.190.10 131 250 4.2E-58 T 12-10-2018 VAPA_2c12010 e3402b6a252ea388f38ff7c21bc647f1 323 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 46 318 3.1E-55 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_2c12010 e3402b6a252ea388f38ff7c21bc647f1 323 Gene3D G3DSA:3.40.190.150 28 311 1.2E-79 T 12-10-2018 VAPA_2c12010 e3402b6a252ea388f38ff7c21bc647f1 323 Gene3D G3DSA:3.40.190.10 123 246 1.2E-79 T 12-10-2018 VAPA_2c12010 e3402b6a252ea388f38ff7c21bc647f1 323 SUPERFAMILY SSF53850 118 285 1.09E-5 T 12-10-2018 VAPA_2c12010 e3402b6a252ea388f38ff7c21bc647f1 323 PIRSF PIRSF017082 2 322 4.4E-58 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c31000 2ef6c0b304d6b7e86d81156c80ad4da6 765 Pfam PF00593 TonB dependent receptor 263 761 6.6E-48 T 12-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel VAPA_1c31000 2ef6c0b304d6b7e86d81156c80ad4da6 765 Gene3D G3DSA:2.40.170.20 191 762 2.0E-84 T 12-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily VAPA_1c31000 2ef6c0b304d6b7e86d81156c80ad4da6 765 Pfam PF07715 TonB-dependent Receptor Plug Domain 57 170 6.6E-12 T 12-10-2018 IPR012910 TonB-dependent receptor, plug domain VAPA_1c31000 2ef6c0b304d6b7e86d81156c80ad4da6 765 SUPERFAMILY SSF56935 32 762 6.23E-104 T 12-10-2018 VAPA_1c31000 2ef6c0b304d6b7e86d81156c80ad4da6 765 Gene3D G3DSA:2.170.130.10 42 173 1.7E-10 T 12-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily VAPA_1c00360 15888012e1c857943d7d6c2963f6aa54 229 Pfam PF00486 Transcriptional regulatory protein, C terminal 154 225 2.4E-15 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 VAPA_1c00360 15888012e1c857943d7d6c2963f6aa54 229 SMART SM00448 1 120 6.9E-31 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_1c00360 15888012e1c857943d7d6c2963f6aa54 229 SUPERFAMILY SSF46894 126 227 2.3E-20 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 VAPA_1c00360 15888012e1c857943d7d6c2963f6aa54 229 SMART SM00862 152 225 5.5E-16 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 VAPA_1c00360 15888012e1c857943d7d6c2963f6aa54 229 Gene3D G3DSA:3.40.50.2300 1 131 6.5E-34 T 12-10-2018 VAPA_1c00360 15888012e1c857943d7d6c2963f6aa54 229 Gene3D G3DSA:1.10.10.10 132 229 8.2E-23 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c00360 15888012e1c857943d7d6c2963f6aa54 229 Pfam PF00072 Response regulator receiver domain 3 120 1.5E-19 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_1c00360 15888012e1c857943d7d6c2963f6aa54 229 SUPERFAMILY SSF52172 1 134 5.69E-32 T 12-10-2018 IPR011006 CheY-like superfamily VAPA_1c43250 1a0adc4c2865e4696e617a00a3067966 559 Pfam PF01514 Secretory protein of YscJ/FliF family 35 224 9.7E-74 T 12-10-2018 IPR006182 Secretory protein YscJ/FliF VAPA_1c43250 1a0adc4c2865e4696e617a00a3067966 559 TIGRFAM TIGR00206 fliF: flagellar M-ring protein FliF 17 558 6.0E-127 T 12-10-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 VAPA_1c43250 1a0adc4c2865e4696e617a00a3067966 559 PRINTS PR01009 Flagellar M-ring protein signature 366 390 1.0E-39 T 12-10-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 VAPA_1c43250 1a0adc4c2865e4696e617a00a3067966 559 PRINTS PR01009 Flagellar M-ring protein signature 125 143 1.0E-39 T 12-10-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 VAPA_1c43250 1a0adc4c2865e4696e617a00a3067966 559 PRINTS PR01009 Flagellar M-ring protein signature 200 218 1.0E-39 T 12-10-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 VAPA_1c43250 1a0adc4c2865e4696e617a00a3067966 559 PRINTS PR01009 Flagellar M-ring protein signature 269 287 1.0E-39 T 12-10-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 VAPA_1c43250 1a0adc4c2865e4696e617a00a3067966 559 PRINTS PR01009 Flagellar M-ring protein signature 157 171 1.0E-39 T 12-10-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 VAPA_1c43250 1a0adc4c2865e4696e617a00a3067966 559 Gene3D G3DSA:3.30.300.30 125 228 4.1E-11 T 12-10-2018 VAPA_1c43250 1a0adc4c2865e4696e617a00a3067966 559 PIRSF PIRSF004862 17 559 1.7E-147 T 12-10-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 VAPA_1c43250 1a0adc4c2865e4696e617a00a3067966 559 Pfam PF08345 Flagellar M-ring protein C-terminal 256 442 1.5E-50 T 12-10-2018 IPR013556 Flagellar M-ring C-terminal VAPA_1c02870 ffc59b3efe7d881c94662d196fcccd75 366 Pfam PF01168 Alanine racemase, N-terminal domain 9 218 8.7E-67 T 12-10-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 VAPA_1c02870 ffc59b3efe7d881c94662d196fcccd75 366 Hamap MF_01201 Alanine racemase. 2 363 32.643 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 VAPA_1c02870 ffc59b3efe7d881c94662d196fcccd75 366 ProSitePatterns PS00395 Alanine racemase pyridoxal-phosphate attachment site. 32 42 - T 12-10-2018 IPR020622 Alanine racemase, pyridoxal-phosphate attachment site KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 VAPA_1c02870 ffc59b3efe7d881c94662d196fcccd75 366 SMART SM01005 233 363 2.1E-60 T 12-10-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 VAPA_1c02870 ffc59b3efe7d881c94662d196fcccd75 366 Pfam PF00842 Alanine racemase, C-terminal domain 234 359 3.7E-40 T 12-10-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 VAPA_1c02870 ffc59b3efe7d881c94662d196fcccd75 366 Gene3D G3DSA:2.40.37.10 217 358 1.2E-108 T 12-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 VAPA_1c02870 ffc59b3efe7d881c94662d196fcccd75 366 Gene3D G3DSA:3.20.20.10 11 216 1.2E-108 T 12-10-2018 IPR029066 PLP-binding barrel VAPA_1c02870 ffc59b3efe7d881c94662d196fcccd75 366 SUPERFAMILY SSF51419 9 234 1.13E-59 T 12-10-2018 IPR029066 PLP-binding barrel VAPA_1c02870 ffc59b3efe7d881c94662d196fcccd75 366 PRINTS PR00992 Alanine racemase signature 121 133 1.1E-60 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 VAPA_1c02870 ffc59b3efe7d881c94662d196fcccd75 366 PRINTS PR00992 Alanine racemase signature 191 218 1.1E-60 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 VAPA_1c02870 ffc59b3efe7d881c94662d196fcccd75 366 PRINTS PR00992 Alanine racemase signature 345 358 1.1E-60 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 VAPA_1c02870 ffc59b3efe7d881c94662d196fcccd75 366 PRINTS PR00992 Alanine racemase signature 27 43 1.1E-60 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 VAPA_1c02870 ffc59b3efe7d881c94662d196fcccd75 366 PRINTS PR00992 Alanine racemase signature 249 264 1.1E-60 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 VAPA_1c02870 ffc59b3efe7d881c94662d196fcccd75 366 PRINTS PR00992 Alanine racemase signature 266 281 1.1E-60 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 VAPA_1c02870 ffc59b3efe7d881c94662d196fcccd75 366 PRINTS PR00992 Alanine racemase signature 61 79 1.1E-60 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 VAPA_1c02870 ffc59b3efe7d881c94662d196fcccd75 366 PRINTS PR00992 Alanine racemase signature 155 166 1.1E-60 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 VAPA_1c02870 ffc59b3efe7d881c94662d196fcccd75 366 PRINTS PR00992 Alanine racemase signature 287 304 1.1E-60 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 VAPA_1c02870 ffc59b3efe7d881c94662d196fcccd75 366 TIGRFAM TIGR00492 alr: alanine racemase 4 359 6.2E-103 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 VAPA_1c02870 ffc59b3efe7d881c94662d196fcccd75 366 SUPERFAMILY SSF50621 228 360 7.32E-44 T 12-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 VAPA_1c35010 9ba2dacb30cadda9e642b6d2d3a4c53c 1179 Pfam PF09899 Putative amidoligase enzyme (DUF2126) 276 1178 0.0 T 12-10-2018 IPR018667 Domain of unknown function DUF2126 VAPA_1c35010 9ba2dacb30cadda9e642b6d2d3a4c53c 1179 Pfam PF01841 Transglutaminase-like superfamily 130 246 3.1E-17 T 12-10-2018 IPR002931 Transglutaminase-like VAPA_1c35010 9ba2dacb30cadda9e642b6d2d3a4c53c 1179 SUPERFAMILY SSF54001 8 337 1.84E-70 T 12-10-2018 IPR038765 Papain-like cysteine peptidase superfamily VAPA_1c35010 9ba2dacb30cadda9e642b6d2d3a4c53c 1179 Pfam PF08379 Bacterial transglutaminase-like N-terminal region 6 84 1.6E-26 T 12-10-2018 IPR013589 Bacterial transglutaminase-like, N-terminal VAPA_1c35010 9ba2dacb30cadda9e642b6d2d3a4c53c 1179 SMART SM00460 172 248 2.5E-15 T 12-10-2018 IPR002931 Transglutaminase-like VAPA_1c35010 9ba2dacb30cadda9e642b6d2d3a4c53c 1179 Gene3D G3DSA:3.10.620.30 96 280 7.9E-26 T 12-10-2018 VAPA_1c48830 1a00aa437a6742c1a435034e8ab11955 303 Pfam PF00849 RNA pseudouridylate synthase 99 245 2.6E-23 T 12-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 VAPA_1c48830 1a00aa437a6742c1a435034e8ab11955 303 SUPERFAMILY SSF55120 84 295 9.36E-49 T 12-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 VAPA_1c48830 1a00aa437a6742c1a435034e8ab11955 303 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 137 151 - T 12-10-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 VAPA_1c48830 1a00aa437a6742c1a435034e8ab11955 303 Gene3D G3DSA:3.30.2350.10 85 297 1.8E-43 T 12-10-2018 VAPA_1c06570 1e8d58593ae170bff1186e243bfe8f7c 276 Pfam PF00149 Calcineurin-like phosphoesterase 1 238 3.3E-12 T 12-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 VAPA_1c06570 1e8d58593ae170bff1186e243bfe8f7c 276 SUPERFAMILY SSF56300 1 261 1.9E-23 T 12-10-2018 VAPA_1c33690 a624b6065b9a94db5f1c3b74ff37cc15 468 Pfam PF02515 CoA-transferase family III 206 401 1.9E-46 T 12-10-2018 IPR003673 CoA-transferase family III GO:0003824 VAPA_1c33690 a624b6065b9a94db5f1c3b74ff37cc15 468 SUPERFAMILY SSF89796 204 406 5.23E-55 T 12-10-2018 IPR023606 CoA-transferase family III domain superfamily VAPA_1c33690 a624b6065b9a94db5f1c3b74ff37cc15 468 Gene3D G3DSA:3.40.50.10540 201 455 6.2E-60 T 12-10-2018 IPR023606 CoA-transferase family III domain superfamily VAPA_1c33690 a624b6065b9a94db5f1c3b74ff37cc15 468 SUPERFAMILY SSF89796 28 202 5.49E-25 T 12-10-2018 IPR023606 CoA-transferase family III domain superfamily VAPA_1c33760 d9deb6c470794a23f97ea359f3b2fd02 327 Pfam PF00682 HMGL-like 11 279 5.0E-47 T 12-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 VAPA_1c33760 d9deb6c470794a23f97ea359f3b2fd02 327 SUPERFAMILY SSF51569 6 298 6.96E-74 T 12-10-2018 VAPA_1c33760 d9deb6c470794a23f97ea359f3b2fd02 327 Gene3D G3DSA:3.20.20.70 6 300 3.0E-110 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 VAPA_1c13880 574e682c81b6d981793e3d3463e395af 329 Gene3D G3DSA:3.40.190.10 133 256 1.7E-103 T 12-10-2018 VAPA_1c13880 574e682c81b6d981793e3d3463e395af 329 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 55 309 1.5E-79 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c13880 574e682c81b6d981793e3d3463e395af 329 PIRSF PIRSF017082 3 325 8.4E-72 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c13880 574e682c81b6d981793e3d3463e395af 329 Gene3D G3DSA:3.40.190.150 39 320 1.7E-103 T 12-10-2018 VAPA_1c13880 574e682c81b6d981793e3d3463e395af 329 SUPERFAMILY SSF53850 42 289 1.12E-13 T 12-10-2018 VAPA_1c28590 d8910b2163de87debfb1004c2e1b785d 221 Gene3D G3DSA:3.30.460.10 9 121 1.1E-30 T 12-10-2018 VAPA_1c28590 d8910b2163de87debfb1004c2e1b785d 221 Pfam PF02410 Ribosomal silencing factor during starvation 17 112 1.0E-22 T 12-10-2018 VAPA_1c28590 d8910b2163de87debfb1004c2e1b785d 221 SUPERFAMILY SSF81301 10 117 2.94E-32 T 12-10-2018 VAPA_1c28590 d8910b2163de87debfb1004c2e1b785d 221 Hamap MF_01477 Ribosomal silencing factor RsfS [rsfS]. 11 113 21.722 T 12-10-2018 IPR004394 Protein Iojap/ribosomal silencing factor RsfS VAPA_1c28590 d8910b2163de87debfb1004c2e1b785d 221 TIGRFAM TIGR00090 rsfS_iojap_ybeB: ribosome silencing factor 16 112 3.6E-29 T 12-10-2018 IPR004394 Protein Iojap/ribosomal silencing factor RsfS VAPA_1c41070 ddc13b97c4b1da856698ec1e53052710 329 Gene3D G3DSA:2.60.120.330 1 319 1.4E-96 T 12-10-2018 IPR027443 Isopenicillin N synthase-like VAPA_1c41070 ddc13b97c4b1da856698ec1e53052710 329 SUPERFAMILY SSF51197 1 316 3.78E-90 T 12-10-2018 VAPA_1c41070 ddc13b97c4b1da856698ec1e53052710 329 Pfam PF03171 2OG-Fe(II) oxygenase superfamily 177 276 1.9E-21 T 12-10-2018 IPR005123 Oxoglutarate/iron-dependent dioxygenase GO:0016491|GO:0055114 VAPA_1c41070 ddc13b97c4b1da856698ec1e53052710 329 PRINTS PR00682 Isopenicillin N synthase signature 149 165 6.5E-12 T 12-10-2018 VAPA_1c41070 ddc13b97c4b1da856698ec1e53052710 329 PRINTS PR00682 Isopenicillin N synthase signature 234 260 6.5E-12 T 12-10-2018 VAPA_1c41070 ddc13b97c4b1da856698ec1e53052710 329 PRINTS PR00682 Isopenicillin N synthase signature 26 43 6.5E-12 T 12-10-2018 VAPA_1c41070 ddc13b97c4b1da856698ec1e53052710 329 Pfam PF14226 non-haem dioxygenase in morphine synthesis N-terminal 3 128 3.1E-27 T 12-10-2018 IPR026992 Non-haem dioxygenase N-terminal domain VAPA_1c15360 da501651ebc1b58d88f547b188eb2d6f 631 Pfam PF07670 Nucleoside recognition 470 600 1.1E-27 T 12-10-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 VAPA_1c15360 da501651ebc1b58d88f547b188eb2d6f 631 Pfam PF07670 Nucleoside recognition 299 391 8.8E-11 T 12-10-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 VAPA_1c15360 da501651ebc1b58d88f547b188eb2d6f 631 Pfam PF07664 Ferrous iron transport protein B C terminus 411 463 1.0E-17 T 12-10-2018 IPR011640 Ferrous iron transport protein B, C-terminal GO:0015093|GO:0015684|GO:0016021 VAPA_1c15360 da501651ebc1b58d88f547b188eb2d6f 631 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 21 41 1.1E-5 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 VAPA_1c15360 da501651ebc1b58d88f547b188eb2d6f 631 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 42 60 1.1E-5 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 VAPA_1c15360 da501651ebc1b58d88f547b188eb2d6f 631 Gene3D G3DSA:3.40.50.300 19 197 8.3E-37 T 12-10-2018 VAPA_1c15360 da501651ebc1b58d88f547b188eb2d6f 631 Pfam PF02421 Ferrous iron transport protein B 20 178 2.8E-51 T 12-10-2018 IPR030389 FeoB-type guanine nucleotide-binding (G) domain GO:0005525 VAPA_1c15360 da501651ebc1b58d88f547b188eb2d6f 631 SUPERFAMILY SSF52540 18 200 2.44E-29 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_2c13030 c0e63edb62edbe0162fac8cc437deba7 59 Pfam PF01695 IstB-like ATP binding protein 6 35 2.8E-6 T 12-10-2018 IPR002611 IstB-like ATP-binding protein GO:0005524 VAPA_2c13030 c0e63edb62edbe0162fac8cc437deba7 59 Gene3D G3DSA:3.40.50.300 1 50 1.4E-7 T 12-10-2018 VAPA_1c52600 efa01f812cfcef98d4a78e258ec6c2d7 347 TIGRFAM TIGR00113 queA: S-adenosylmethionine:tRNA ribosyltransferase-isomerase 5 342 1.7E-121 T 12-10-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 VAPA_1c52600 efa01f812cfcef98d4a78e258ec6c2d7 347 Gene3D G3DSA:2.40.10.240 65 168 1.3E-105 T 12-10-2018 VAPA_1c52600 efa01f812cfcef98d4a78e258ec6c2d7 347 Pfam PF02547 Queuosine biosynthesis protein 6 342 1.2E-124 T 12-10-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 VAPA_1c52600 efa01f812cfcef98d4a78e258ec6c2d7 347 SUPERFAMILY SSF111337 5 342 1.18E-124 T 12-10-2018 IPR036100 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA superfamily GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 VAPA_1c52600 efa01f812cfcef98d4a78e258ec6c2d7 347 Gene3D G3DSA:3.40.1780.10 17 342 1.3E-105 T 12-10-2018 VAPA_1c52600 efa01f812cfcef98d4a78e258ec6c2d7 347 Hamap MF_00113 S-adenosylmethionine:tRNA ribosyltransferase-isomerase [queA]. 4 343 43.406 T 12-10-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 VAPA_1c45420 2d32764e1126e4c1f62057714ca7ed56 222 PIRSF PIRSF004553 30 214 9.2E-36 T 12-10-2018 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 VAPA_1c45420 2d32764e1126e4c1f62057714ca7ed56 222 Gene3D G3DSA:3.40.50.150 22 221 5.1E-42 T 12-10-2018 VAPA_1c45420 2d32764e1126e4c1f62057714ca7ed56 222 SUPERFAMILY SSF53335 31 212 2.43E-37 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase VAPA_1c45420 2d32764e1126e4c1f62057714ca7ed56 222 Pfam PF03602 Conserved hypothetical protein 95 31 192 8.6E-40 T 12-10-2018 VAPA_1c24720 ed652d53abb6fdcd331ff85c51c30aac 130 Gene3D G3DSA:1.20.120.550 3 129 2.2E-18 T 12-10-2018 IPR023352 Membrane associated eicosanoid/glutathione metabolism-like domain superfamily VAPA_1c24720 ed652d53abb6fdcd331ff85c51c30aac 130 Pfam PF01124 MAPEG family 8 129 3.8E-24 T 12-10-2018 IPR001129 Membrane-associated, eicosanoid/glutathione metabolism (MAPEG) protein VAPA_1c24720 ed652d53abb6fdcd331ff85c51c30aac 130 SUPERFAMILY SSF161084 6 127 1.02E-24 T 12-10-2018 IPR023352 Membrane associated eicosanoid/glutathione metabolism-like domain superfamily VAPA_1c52820 26fb8c364180e34cc0131c32ad05c11c 319 SUPERFAMILY SSF55821 2 197 9.77E-56 T 12-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily VAPA_1c52820 26fb8c364180e34cc0131c32ad05c11c 319 TIGRFAM TIGR00057 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family 1 194 1.0E-45 T 12-10-2018 IPR006070 YrdC-like domain GO:0003725 VAPA_1c52820 26fb8c364180e34cc0131c32ad05c11c 319 Gene3D G3DSA:3.40.50.11030 202 319 1.4E-14 T 12-10-2018 IPR038385 Threonylcarbamoyl-AMP synthase, C-terminal domain superfamily VAPA_1c52820 26fb8c364180e34cc0131c32ad05c11c 319 Pfam PF03481 Putative GTP-binding controlling metal-binding 187 317 3.7E-19 T 12-10-2018 IPR005145 Putative GTP-binding controlling metal-binding domain VAPA_1c52820 26fb8c364180e34cc0131c32ad05c11c 319 Pfam PF01300 Telomere recombination 3 185 1.5E-49 T 12-10-2018 IPR006070 YrdC-like domain GO:0003725 VAPA_1c52820 26fb8c364180e34cc0131c32ad05c11c 319 Gene3D G3DSA:3.90.870.10 1 200 4.8E-71 T 12-10-2018 VAPA_1c52820 26fb8c364180e34cc0131c32ad05c11c 319 PIRSF PIRSF004930 1 319 3.1E-97 T 12-10-2018 IPR010923 tRNA threonylcarbamoyladenosine biosynthesis protein SUA5 VAPA_1c29070 8059790691121796ea7d032d2d0aa309 193 ProSitePatterns PS00088 Manganese and iron superoxide dismutases signature. 157 164 - T 12-10-2018 IPR019833 Manganese/iron superoxide dismutase, binding site GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 VAPA_1c29070 8059790691121796ea7d032d2d0aa309 193 Pfam PF02777 Iron/manganese superoxide dismutases, C-terminal domain 89 190 2.7E-34 T 12-10-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 VAPA_1c29070 8059790691121796ea7d032d2d0aa309 193 Gene3D G3DSA:1.10.287.990 20 81 5.1E-25 T 12-10-2018 IPR036324 Manganese/iron superoxide dismutase, N-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 VAPA_1c29070 8059790691121796ea7d032d2d0aa309 193 SUPERFAMILY SSF46609 1 84 3.8E-33 T 12-10-2018 IPR036324 Manganese/iron superoxide dismutase, N-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 VAPA_1c29070 8059790691121796ea7d032d2d0aa309 193 PRINTS PR01703 Manganese superoxide dismutase signature 65 78 3.1E-22 T 12-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 VAPA_1c29070 8059790691121796ea7d032d2d0aa309 193 PRINTS PR01703 Manganese superoxide dismutase signature 6 17 3.1E-22 T 12-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 VAPA_1c29070 8059790691121796ea7d032d2d0aa309 193 PRINTS PR01703 Manganese superoxide dismutase signature 27 40 3.1E-22 T 12-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 VAPA_1c29070 8059790691121796ea7d032d2d0aa309 193 PRINTS PR01703 Manganese superoxide dismutase signature 118 126 3.1E-22 T 12-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 VAPA_1c29070 8059790691121796ea7d032d2d0aa309 193 PRINTS PR01703 Manganese superoxide dismutase signature 155 167 3.1E-22 T 12-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 VAPA_1c29070 8059790691121796ea7d032d2d0aa309 193 PIRSF PIRSF000349 1 193 2.2E-78 T 12-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 VAPA_1c29070 8059790691121796ea7d032d2d0aa309 193 SUPERFAMILY SSF54719 85 192 1.44E-40 T 12-10-2018 IPR036314 Manganese/iron superoxide dismutase, C-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 VAPA_1c29070 8059790691121796ea7d032d2d0aa309 193 Gene3D G3DSA:2.40.500.20 83 193 9.1E-38 T 12-10-2018 IPR036314 Manganese/iron superoxide dismutase, C-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 VAPA_1c29070 8059790691121796ea7d032d2d0aa309 193 Pfam PF00081 Iron/manganese superoxide dismutases, alpha-hairpin domain 3 82 4.3E-31 T 12-10-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 VAPA_1c53910 a8b9dabd9c0888c065abe47999b91b50 644 Pfam PF13727 CoA-binding domain 81 240 1.4E-9 T 12-10-2018 VAPA_1c53910 a8b9dabd9c0888c065abe47999b91b50 644 SUPERFAMILY SSF53335 144 334 6.31E-17 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase VAPA_1c53910 a8b9dabd9c0888c065abe47999b91b50 644 Gene3D G3DSA:3.40.50.720 281 628 1.3E-108 T 12-10-2018 VAPA_1c53910 a8b9dabd9c0888c065abe47999b91b50 644 Gene3D G3DSA:3.40.50.720 145 266 8.1E-33 T 12-10-2018 VAPA_1c53910 a8b9dabd9c0888c065abe47999b91b50 644 Pfam PF02719 Polysaccharide biosynthesis protein 286 597 1.2E-117 T 12-10-2018 IPR003869 Polysaccharide biosynthesis protein, CapD-like domain VAPA_1c53910 a8b9dabd9c0888c065abe47999b91b50 644 SUPERFAMILY SSF51735 284 603 9.51E-49 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c00820 4b76efc04f26bc6e1a380419a8ba301b 236 SMART SM00100 24 142 1.3E-13 T 12-10-2018 IPR000595 Cyclic nucleotide-binding domain VAPA_1c00820 4b76efc04f26bc6e1a380419a8ba301b 236 Pfam PF13545 Crp-like helix-turn-helix domain 164 232 1.6E-12 T 12-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 VAPA_1c00820 4b76efc04f26bc6e1a380419a8ba301b 236 SUPERFAMILY SSF51206 17 149 4.06E-27 T 12-10-2018 IPR018490 Cyclic nucleotide-binding-like VAPA_1c00820 4b76efc04f26bc6e1a380419a8ba301b 236 Pfam PF00027 Cyclic nucleotide-binding domain 43 127 1.4E-16 T 12-10-2018 IPR000595 Cyclic nucleotide-binding domain VAPA_1c00820 4b76efc04f26bc6e1a380419a8ba301b 236 SUPERFAMILY SSF46785 159 235 1.17E-14 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c00820 4b76efc04f26bc6e1a380419a8ba301b 236 Gene3D G3DSA:2.60.120.10 14 159 3.1E-22 T 12-10-2018 IPR014710 RmlC-like jelly roll fold VAPA_1c00820 4b76efc04f26bc6e1a380419a8ba301b 236 Gene3D G3DSA:1.10.10.10 160 236 3.4E-13 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c05710 747d9cab58720c60867367cb1e0ee6d4 375 Gene3D G3DSA:3.30.590.20 2 372 6.4E-97 T 12-10-2018 VAPA_1c05710 747d9cab58720c60867367cb1e0ee6d4 375 SUPERFAMILY SSF55931 5 369 6.08E-109 T 12-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 VAPA_1c05710 747d9cab58720c60867367cb1e0ee6d4 375 Hamap MF_01609 Glutamate--cysteine ligase [gshA]. 1 375 99.747 T 12-10-2018 IPR011793 Putative glutamate--cysteine ligase YbdK GO:0016879 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 VAPA_1c05710 747d9cab58720c60867367cb1e0ee6d4 375 TIGRFAM TIGR02050 gshA_cyan_rel: carboxylate-amine ligase, YbdK family 15 298 3.6E-98 T 12-10-2018 IPR011793 Putative glutamate--cysteine ligase YbdK GO:0016879 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 VAPA_1c05710 747d9cab58720c60867367cb1e0ee6d4 375 Pfam PF04107 Glutamate-cysteine ligase family 2(GCS2) 15 292 2.5E-56 T 12-10-2018 IPR006336 Glutamate--cysteine ligase, GCS2 GO:0004357|GO:0042398 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 VAPA_1c34400 7c179e19a4919fe030b693d02e5e37c1 268 Gene3D G3DSA:3.40.50.1820 12 268 2.6E-28 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c34400 7c179e19a4919fe030b693d02e5e37c1 268 SUPERFAMILY SSF53474 21 268 6.87E-28 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c34400 7c179e19a4919fe030b693d02e5e37c1 268 Pfam PF12697 Alpha/beta hydrolase family 45 260 8.0E-8 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 VAPA_1c01370 72eca560b418aa15598646d4ecbd0ebf 332 SUPERFAMILY SSF50129 26 144 1.73E-24 T 12-10-2018 IPR011032 GroES-like superfamily VAPA_1c01370 72eca560b418aa15598646d4ecbd0ebf 332 SUPERFAMILY SSF51735 124 301 6.54E-32 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c01370 72eca560b418aa15598646d4ecbd0ebf 332 SMART SM00829 19 330 2.3E-11 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 VAPA_1c01370 72eca560b418aa15598646d4ecbd0ebf 332 Gene3D G3DSA:3.90.180.10 21 324 5.0E-60 T 12-10-2018 VAPA_1c01370 72eca560b418aa15598646d4ecbd0ebf 332 Gene3D G3DSA:3.40.50.720 132 300 5.0E-60 T 12-10-2018 VAPA_1c01370 72eca560b418aa15598646d4ecbd0ebf 332 Pfam PF00107 Zinc-binding dehydrogenase 164 273 4.2E-13 T 12-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 VAPA_2c03760 df575fe0dc695eaf2926578a42477c8a 271 ProSitePatterns PS00211 ABC transporters family signature. 144 158 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_2c03760 df575fe0dc695eaf2926578a42477c8a 271 Pfam PF00005 ABC transporter 32 172 2.6E-31 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_2c03760 df575fe0dc695eaf2926578a42477c8a 271 SMART SM00382 41 222 7.9E-18 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_2c03760 df575fe0dc695eaf2926578a42477c8a 271 Gene3D G3DSA:3.40.50.300 12 256 7.9E-66 T 12-10-2018 VAPA_2c03760 df575fe0dc695eaf2926578a42477c8a 271 SUPERFAMILY SSF52540 13 234 1.91E-71 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c13300 92daacdeb7b45ade93a09c2eee33946a 273 Gene3D G3DSA:1.10.3720.10 14 269 2.6E-50 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c13300 92daacdeb7b45ade93a09c2eee33946a 273 SUPERFAMILY SSF161098 10 266 9.81E-47 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c13300 92daacdeb7b45ade93a09c2eee33946a 273 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 79 266 1.6E-14 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 VAPA_1c36100 666227da0b5fc295a4597787daaf2e72 181 TIGRFAM TIGR01971 NuoI: NADH-quinone oxidoreductase, chain I 38 159 6.3E-46 T 12-10-2018 IPR010226 NADH-quinone oxidoreductase, chain I GO:0016020|GO:0016651|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VAPA_1c36100 666227da0b5fc295a4597787daaf2e72 181 SUPERFAMILY SSF54862 55 164 2.18E-25 T 12-10-2018 VAPA_1c36100 666227da0b5fc295a4597787daaf2e72 181 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 121 132 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site VAPA_1c36100 666227da0b5fc295a4597787daaf2e72 181 Pfam PF12838 4Fe-4S dicluster domain 81 134 2.6E-11 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain VAPA_1c36100 666227da0b5fc295a4597787daaf2e72 181 Gene3D G3DSA:3.30.70.3270 55 181 3.8E-38 T 12-10-2018 VAPA_1c36100 666227da0b5fc295a4597787daaf2e72 181 Hamap MF_01351 NAD(P)H-quinone oxidoreductase subunit I, chloroplastic [ndhI]. 29 178 28.299 T 12-10-2018 IPR010226 NADH-quinone oxidoreductase, chain I GO:0016020|GO:0016651|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VAPA_1c31690 4806ceb1210563d0ed9122205f547761 147 TIGRFAM TIGR00244 TIGR00244: transcriptional regulator NrdR 1 145 9.3E-54 T 12-10-2018 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 VAPA_1c31690 4806ceb1210563d0ed9122205f547761 147 Hamap MF_00440 Transcriptional repressor NrdR [nrdR]. 1 147 79.435 T 12-10-2018 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 VAPA_1c31690 4806ceb1210563d0ed9122205f547761 147 Pfam PF03477 ATP cone domain 50 136 6.3E-14 T 12-10-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 VAPA_1c24580 4a7ef5b7af184ebf61d680ee14f3c096 447 PIRSF PIRSF006603 12 445 3.9E-51 T 12-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 VAPA_1c24580 4a7ef5b7af184ebf61d680ee14f3c096 447 Pfam PF01554 MatE 242 393 1.2E-23 T 12-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 VAPA_1c24580 4a7ef5b7af184ebf61d680ee14f3c096 447 Pfam PF01554 MatE 16 172 9.0E-19 T 12-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 VAPA_1c24580 4a7ef5b7af184ebf61d680ee14f3c096 447 TIGRFAM TIGR00797 matE: MATE efflux family protein 16 408 5.9E-67 T 12-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 VAPA_1c40360 78d16456f2333f18eb50d60f466cd6b9 719 SUPERFAMILY SSF52518 22 252 8.34E-24 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold VAPA_1c40360 78d16456f2333f18eb50d60f466cd6b9 719 SUPERFAMILY SSF52518 409 602 4.47E-21 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold VAPA_1c40360 78d16456f2333f18eb50d60f466cd6b9 719 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 442 588 1.2E-15 T 12-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 VAPA_1c40360 78d16456f2333f18eb50d60f466cd6b9 719 Gene3D G3DSA:3.40.50.970 6 201 8.7E-22 T 12-10-2018 VAPA_1c40360 78d16456f2333f18eb50d60f466cd6b9 719 Gene3D G3DSA:3.40.50.970 426 597 3.8E-9 T 12-10-2018 VAPA_1c40360 78d16456f2333f18eb50d60f466cd6b9 719 SUPERFAMILY SSF54862 600 677 2.12E-7 T 12-10-2018 VAPA_1c05340 468b313575ae792d5f62b4ce13adfcc1 396 Gene3D G3DSA:3.30.1540.10 224 322 2.4E-116 T 12-10-2018 VAPA_1c05340 468b313575ae792d5f62b4ce13adfcc1 396 Gene3D G3DSA:3.40.50.10540 8 387 2.4E-116 T 12-10-2018 IPR023606 CoA-transferase family III domain superfamily VAPA_1c05340 468b313575ae792d5f62b4ce13adfcc1 396 SUPERFAMILY SSF89796 4 392 4.06E-123 T 12-10-2018 IPR023606 CoA-transferase family III domain superfamily VAPA_1c05340 468b313575ae792d5f62b4ce13adfcc1 396 Pfam PF02515 CoA-transferase family III 10 370 4.1E-112 T 12-10-2018 IPR003673 CoA-transferase family III GO:0003824 VAPA_1c08820 28fd59850dc717cc62470ceedeff47e5 141 Gene3D G3DSA:3.10.129.10 9 141 4.2E-36 T 12-10-2018 VAPA_1c08820 28fd59850dc717cc62470ceedeff47e5 141 SUPERFAMILY SSF54637 19 139 1.55E-35 T 12-10-2018 IPR029069 HotDog domain superfamily VAPA_1c08820 28fd59850dc717cc62470ceedeff47e5 141 Pfam PF03061 Thioesterase superfamily 36 107 8.8E-15 T 12-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 VAPA_1c41300 393b1f27b882ba189dbe22368856e2f2 139 SUPERFAMILY SSF81901 47 125 2.22E-7 T 12-10-2018 VAPA_1c41300 393b1f27b882ba189dbe22368856e2f2 139 Gene3D G3DSA:1.25.40.10 37 131 2.6E-10 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 VAPA_1c10090 00a3d5190e097f5f922b31f2d72b7d2c 205 Gene3D G3DSA:3.40.80.10 17 192 1.6E-55 T 12-10-2018 IPR036505 N-acetylmuramoyl-L-alanine amidase/PGRP domain superfamily GO:0008745|GO:0009253 Reactome: R-HSA-6803157 VAPA_1c10090 00a3d5190e097f5f922b31f2d72b7d2c 205 SMART SM00644 31 179 3.6E-42 T 12-10-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 VAPA_1c10090 00a3d5190e097f5f922b31f2d72b7d2c 205 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 42 179 1.3E-28 T 12-10-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 VAPA_1c10090 00a3d5190e097f5f922b31f2d72b7d2c 205 SUPERFAMILY SSF55846 19 191 2.22E-60 T 12-10-2018 IPR036505 N-acetylmuramoyl-L-alanine amidase/PGRP domain superfamily GO:0008745|GO:0009253 Reactome: R-HSA-6803157 VAPA_1c45750 46b3adc7e2ed980556245f29fb909ddf 257 SUPERFAMILY SSF52096 1 255 3.11E-65 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily VAPA_1c45750 46b3adc7e2ed980556245f29fb909ddf 257 Pfam PF00378 Enoyl-CoA hydratase/isomerase 11 251 8.7E-37 T 12-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 VAPA_1c45750 46b3adc7e2ed980556245f29fb909ddf 257 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 98 118 - T 12-10-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824 VAPA_1c45750 46b3adc7e2ed980556245f29fb909ddf 257 Gene3D G3DSA:3.90.226.10 1 199 7.2E-65 T 12-10-2018 VAPA_1c45750 46b3adc7e2ed980556245f29fb909ddf 257 Gene3D G3DSA:1.10.12.10 200 257 6.0E-24 T 12-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal VAPA_1c30090 0d6a65fe24dee2c66e849dbe1a64b3b3 141 Pfam PF00582 Universal stress protein family 2 140 3.1E-23 T 12-10-2018 IPR006016 UspA VAPA_1c30090 0d6a65fe24dee2c66e849dbe1a64b3b3 141 Gene3D G3DSA:3.40.50.620 1 141 1.8E-26 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold VAPA_1c30090 0d6a65fe24dee2c66e849dbe1a64b3b3 141 PRINTS PR01438 Universal stress protein signature 101 113 3.4E-8 T 12-10-2018 IPR006015 Universal stress protein A VAPA_1c30090 0d6a65fe24dee2c66e849dbe1a64b3b3 141 PRINTS PR01438 Universal stress protein signature 119 141 3.4E-8 T 12-10-2018 IPR006015 Universal stress protein A VAPA_1c30090 0d6a65fe24dee2c66e849dbe1a64b3b3 141 SUPERFAMILY SSF52402 1 141 3.85E-27 T 12-10-2018 VAPA_1c41130 dab44a44ca84ce616a784e00ae3d19ae 132 Pfam PF02566 OsmC-like protein 34 127 9.9E-17 T 12-10-2018 IPR003718 OsmC/Ohr family VAPA_1c41130 dab44a44ca84ce616a784e00ae3d19ae 132 Gene3D G3DSA:3.30.300.20 2 131 1.2E-25 T 12-10-2018 IPR015946 K homology domain-like, alpha/beta VAPA_1c41130 dab44a44ca84ce616a784e00ae3d19ae 132 SUPERFAMILY SSF82784 2 123 3.53E-29 T 12-10-2018 IPR036102 OsmC/Ohr superfamily VAPA_1c36350 098b8123c6bfc642a29950891c202cae 422 Pfam PF07690 Major Facilitator Superfamily 19 345 7.1E-38 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 VAPA_1c36350 098b8123c6bfc642a29950891c202cae 422 SUPERFAMILY SSF103473 9 394 2.35E-57 T 12-10-2018 IPR036259 MFS transporter superfamily VAPA_1c36350 098b8123c6bfc642a29950891c202cae 422 Gene3D G3DSA:1.20.1250.20 9 189 1.7E-36 T 12-10-2018 VAPA_1c36350 098b8123c6bfc642a29950891c202cae 422 Gene3D G3DSA:1.20.1250.20 194 398 2.7E-45 T 12-10-2018 VAPA_1c07940 1e385c700fe37919008369572ca3c824 684 Gene3D G3DSA:3.20.20.80 309 664 1.9E-137 T 12-10-2018 VAPA_1c07940 1e385c700fe37919008369572ca3c824 684 TIGRFAM TIGR03938 deacetyl_PgaB: poly-beta-1,6-N-acetyl-D-glucosamine N-deacetylase PgaB 40 658 1.7E-262 T 12-10-2018 IPR023854 Poly-beta-1,6-N-acetyl-D-glucosamine N-deacetylase PgaB GO:0016810|GO:0043708 VAPA_1c07940 1e385c700fe37919008369572ca3c824 684 Pfam PF14883 Hypothetical glycosyl hydrolase family 13 318 638 4.6E-140 T 12-10-2018 IPR032772 Poly-beta-1,6-N-acetyl-D-glucosamine N-deacetylase PgaB, C-terminal VAPA_1c07940 1e385c700fe37919008369572ca3c824 684 Gene3D G3DSA:3.20.20.370 32 301 1.5E-71 T 12-10-2018 VAPA_1c07940 1e385c700fe37919008369572ca3c824 684 Pfam PF01522 Polysaccharide deacetylase 98 264 3.8E-25 T 12-10-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 VAPA_1c07940 1e385c700fe37919008369572ca3c824 684 SUPERFAMILY SSF88713 62 288 1.11E-35 T 12-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 VAPA_1c11960 0b139d6379041a5b2e3f8b1d38a68ecf 429 Gene3D G3DSA:3.20.20.10 43 287 5.2E-147 T 12-10-2018 IPR029066 PLP-binding barrel VAPA_1c11960 0b139d6379041a5b2e3f8b1d38a68ecf 429 SUPERFAMILY SSF51419 35 294 9.74E-79 T 12-10-2018 IPR029066 PLP-binding barrel VAPA_1c11960 0b139d6379041a5b2e3f8b1d38a68ecf 429 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 66 84 3.6E-24 T 12-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 VAPA_1c11960 0b139d6379041a5b2e3f8b1d38a68ecf 429 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 282 301 3.6E-24 T 12-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 VAPA_1c11960 0b139d6379041a5b2e3f8b1d38a68ecf 429 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 380 393 3.6E-24 T 12-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 VAPA_1c11960 0b139d6379041a5b2e3f8b1d38a68ecf 429 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 86 98 3.6E-24 T 12-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 VAPA_1c11960 0b139d6379041a5b2e3f8b1d38a68ecf 429 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 199 212 3.6E-24 T 12-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 VAPA_1c11960 0b139d6379041a5b2e3f8b1d38a68ecf 429 TIGRFAM TIGR01048 lysA: diaminopimelate decarboxylase 15 422 6.3E-155 T 12-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 VAPA_1c11960 0b139d6379041a5b2e3f8b1d38a68ecf 429 SUPERFAMILY SSF50621 268 423 3.98E-51 T 12-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 VAPA_1c11960 0b139d6379041a5b2e3f8b1d38a68ecf 429 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 52 291 5.5E-67 T 12-10-2018 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 VAPA_1c11960 0b139d6379041a5b2e3f8b1d38a68ecf 429 Hamap MF_02120 Diaminopimelate decarboxylase [lysA]. 24 423 40.1 T 12-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 VAPA_1c11960 0b139d6379041a5b2e3f8b1d38a68ecf 429 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 292 380 5.7E-24 T 12-10-2018 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 VAPA_1c11960 0b139d6379041a5b2e3f8b1d38a68ecf 429 PRINTS PR01181 Diaminopimelate decarboxylase signature 173 182 9.2E-28 T 12-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 VAPA_1c11960 0b139d6379041a5b2e3f8b1d38a68ecf 429 PRINTS PR01181 Diaminopimelate decarboxylase signature 390 412 9.2E-28 T 12-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 VAPA_1c11960 0b139d6379041a5b2e3f8b1d38a68ecf 429 PRINTS PR01181 Diaminopimelate decarboxylase signature 310 328 9.2E-28 T 12-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 VAPA_1c11960 0b139d6379041a5b2e3f8b1d38a68ecf 429 PRINTS PR01181 Diaminopimelate decarboxylase signature 84 101 9.2E-28 T 12-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 VAPA_1c11960 0b139d6379041a5b2e3f8b1d38a68ecf 429 Gene3D G3DSA:2.40.37.10 23 419 5.2E-147 T 12-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 VAPA_1c30880 00cbba5b6b219bb0756a434a3c1b59c5 338 TIGRFAM TIGR00167 cbbA: ketose-bisphosphate aldolase 1 328 1.9E-97 T 12-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 VAPA_1c30880 00cbba5b6b219bb0756a434a3c1b59c5 338 ProSitePatterns PS00806 Fructose-bisphosphate aldolase class-II signature 2. 139 150 - T 12-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 VAPA_1c30880 00cbba5b6b219bb0756a434a3c1b59c5 338 Pfam PF01116 Fructose-bisphosphate aldolase class-II 5 327 1.3E-95 T 12-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 VAPA_1c30880 00cbba5b6b219bb0756a434a3c1b59c5 338 PIRSF PIRSF001359 1 329 1.4E-84 T 12-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 VAPA_1c30880 00cbba5b6b219bb0756a434a3c1b59c5 338 ProSitePatterns PS00602 Fructose-bisphosphate aldolase class-II signature 1. 72 85 - T 12-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 VAPA_1c30880 00cbba5b6b219bb0756a434a3c1b59c5 338 TIGRFAM TIGR01521 FruBisAldo_II_B: fructose-bisphosphate aldolase, class II, Calvin cycle subtype 4 337 7.8E-190 T 12-10-2018 IPR006412 Fructose-bisphosphate aldolase, class II, Calvin cycle subtype GO:0004332|GO:0006096 KEGG: 00010+4.1.2.13|KEGG: 00030+4.1.2.13|KEGG: 00051+4.1.2.13|KEGG: 00680+4.1.2.13|KEGG: 00710+4.1.2.13|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 VAPA_1c30880 00cbba5b6b219bb0756a434a3c1b59c5 338 SUPERFAMILY SSF51569 3 328 6.89E-107 T 12-10-2018 VAPA_1c30880 00cbba5b6b219bb0756a434a3c1b59c5 338 Gene3D G3DSA:3.20.20.70 1 338 4.1E-144 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 VAPA_2c07960 e6d068acad06d319f394ff73fadf5b9c 143 SUPERFAMILY SSF52402 1 129 3.07E-18 T 12-10-2018 VAPA_2c07960 e6d068acad06d319f394ff73fadf5b9c 143 Pfam PF00582 Universal stress protein family 1 129 1.6E-13 T 12-10-2018 IPR006016 UspA VAPA_2c07960 e6d068acad06d319f394ff73fadf5b9c 143 Gene3D G3DSA:3.40.50.620 1 133 3.0E-19 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold VAPA_1c23120 078cb2f7f573678f33b99e08a1f911cb 406 PIRSF PIRSF005572 6 386 3.0E-127 T 12-10-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-7250 VAPA_1c23120 078cb2f7f573678f33b99e08a1f911cb 406 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 199 218 - T 12-10-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site VAPA_1c23120 078cb2f7f573678f33b99e08a1f911cb 406 Hamap MF_00331 Cysteine desulfurase IscS [iscS]. 5 397 52.5 T 12-10-2018 IPR010240 Cysteine desulfurase IscS GO:0030170|GO:0031071|GO:0044571 KEGG: 00730+2.8.1.7|MetaCyc: PWY-7250|Reactome: R-HSA-1362409|Reactome: R-HSA-947581 VAPA_1c23120 078cb2f7f573678f33b99e08a1f911cb 406 Gene3D G3DSA:3.90.1150.10 9 377 2.1E-156 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 VAPA_1c23120 078cb2f7f573678f33b99e08a1f911cb 406 Pfam PF00266 Aminotransferase class-V 9 370 9.5E-84 T 12-10-2018 IPR000192 Aminotransferase class V domain VAPA_1c23120 078cb2f7f573678f33b99e08a1f911cb 406 SUPERFAMILY SSF53383 8 393 1.61E-110 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase VAPA_1c23120 078cb2f7f573678f33b99e08a1f911cb 406 TIGRFAM TIGR02006 IscS: cysteine desulfurase IscS 7 406 6.0E-218 T 12-10-2018 IPR010240 Cysteine desulfurase IscS GO:0030170|GO:0031071|GO:0044571 KEGG: 00730+2.8.1.7|MetaCyc: PWY-7250|Reactome: R-HSA-1362409|Reactome: R-HSA-947581 VAPA_1c23120 078cb2f7f573678f33b99e08a1f911cb 406 Gene3D G3DSA:3.40.640.10 20 264 2.1E-156 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 VAPA_1c21860 70dfa482dc1967d9e601eab6304858f6 280 SMART SM00062 39 263 7.1E-20 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF VAPA_1c21860 70dfa482dc1967d9e601eab6304858f6 280 Gene3D G3DSA:3.40.190.10 43 258 2.9E-38 T 12-10-2018 VAPA_1c21860 70dfa482dc1967d9e601eab6304858f6 280 SUPERFAMILY SSF53850 36 261 7.17E-36 T 12-10-2018 VAPA_1c21860 70dfa482dc1967d9e601eab6304858f6 280 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 40 259 2.7E-34 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF VAPA_1c21860 70dfa482dc1967d9e601eab6304858f6 280 Gene3D G3DSA:3.40.190.10 126 220 2.9E-38 T 12-10-2018 VAPA_1c15380 90bfdff0d9e024fe2c998376711f0ae8 394 Pfam PF01494 FAD binding domain 5 329 2.8E-17 T 12-10-2018 IPR002938 FAD-binding domain GO:0071949 VAPA_1c15380 90bfdff0d9e024fe2c998376711f0ae8 394 SUPERFAMILY SSF54373 182 282 1.41E-10 T 12-10-2018 VAPA_1c15380 90bfdff0d9e024fe2c998376711f0ae8 394 Gene3D G3DSA:3.30.9.30 37 365 1.3E-102 T 12-10-2018 VAPA_1c15380 90bfdff0d9e024fe2c998376711f0ae8 394 SUPERFAMILY SSF51905 4 381 2.16E-52 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c15380 90bfdff0d9e024fe2c998376711f0ae8 394 Gene3D G3DSA:3.50.50.60 5 358 1.3E-102 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c15380 90bfdff0d9e024fe2c998376711f0ae8 394 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 307 323 7.4E-15 T 12-10-2018 VAPA_1c15380 90bfdff0d9e024fe2c998376711f0ae8 394 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 4 26 7.4E-15 T 12-10-2018 VAPA_1c15380 90bfdff0d9e024fe2c998376711f0ae8 394 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 152 167 7.4E-15 T 12-10-2018 VAPA_1c15380 90bfdff0d9e024fe2c998376711f0ae8 394 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 292 307 7.4E-15 T 12-10-2018 VAPA_1c47290 3607f81fdc952ea24863fb94fb485054 613 SUPERFAMILY SSF52540 53 380 4.26E-29 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c47290 3607f81fdc952ea24863fb94fb485054 613 Gene3D G3DSA:3.40.50.300 52 182 5.2E-14 T 12-10-2018 VAPA_1c47290 3607f81fdc952ea24863fb94fb485054 613 Pfam PF13175 AAA ATPase domain 53 95 1.1E-12 T 12-10-2018 VAPA_1c47290 3607f81fdc952ea24863fb94fb485054 613 SMART SM00382 72 378 2.9E-9 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c47290 3607f81fdc952ea24863fb94fb485054 613 Pfam PF13304 AAA domain, putative AbiEii toxin, Type IV TA system 292 362 1.4E-15 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 VAPA_1c47290 3607f81fdc952ea24863fb94fb485054 613 Gene3D G3DSA:3.40.50.300 228 381 4.2E-14 T 12-10-2018 VAPA_2c09150 7ba060f5340649ee5cbfc5dfed5474d1 249 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 246 4.9E-63 T 12-10-2018 VAPA_2c09150 7ba060f5340649ee5cbfc5dfed5474d1 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 124 140 5.2E-40 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c09150 7ba060f5340649ee5cbfc5dfed5474d1 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 210 230 5.2E-40 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c09150 7ba060f5340649ee5cbfc5dfed5474d1 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 5.2E-40 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c09150 7ba060f5340649ee5cbfc5dfed5474d1 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 171 188 5.2E-40 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c09150 7ba060f5340649ee5cbfc5dfed5474d1 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 5.2E-40 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c09150 7ba060f5340649ee5cbfc5dfed5474d1 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 150 169 5.2E-40 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c09150 7ba060f5340649ee5cbfc5dfed5474d1 249 SUPERFAMILY SSF51735 6 247 4.97E-78 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_2c09150 7ba060f5340649ee5cbfc5dfed5474d1 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 150 169 1.4E-6 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c09150 7ba060f5340649ee5cbfc5dfed5474d1 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 130 138 1.4E-6 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c09150 7ba060f5340649ee5cbfc5dfed5474d1 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 79 90 1.4E-6 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c09150 7ba060f5340649ee5cbfc5dfed5474d1 249 Gene3D G3DSA:3.40.50.720 1 248 9.1E-80 T 12-10-2018 VAPA_2c09150 7ba060f5340649ee5cbfc5dfed5474d1 249 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 137 165 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 VAPA_1c00770 fb16176f9970382fe7bf129616e851ad 305 Gene3D G3DSA:3.40.190.10 94 296 4.6E-48 T 12-10-2018 VAPA_1c00770 fb16176f9970382fe7bf129616e851ad 305 Pfam PF03466 LysR substrate binding domain 97 299 3.0E-21 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_1c00770 fb16176f9970382fe7bf129616e851ad 305 Gene3D G3DSA:1.10.10.10 1 88 2.5E-30 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c00770 fb16176f9970382fe7bf129616e851ad 305 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 65 3.0E-19 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c00770 fb16176f9970382fe7bf129616e851ad 305 SUPERFAMILY SSF53850 89 299 7.06E-36 T 12-10-2018 VAPA_1c00770 fb16176f9970382fe7bf129616e851ad 305 Gene3D G3DSA:3.40.190.10 173 272 4.6E-48 T 12-10-2018 VAPA_1c00770 fb16176f9970382fe7bf129616e851ad 305 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 23 34 6.0E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c00770 fb16176f9970382fe7bf129616e851ad 305 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 44 6.0E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c00770 fb16176f9970382fe7bf129616e851ad 305 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 44 55 6.0E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c00770 fb16176f9970382fe7bf129616e851ad 305 SUPERFAMILY SSF46785 2 85 2.24E-19 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c02450 8767e80ca0b5444d0e383de963f3c7e7 171 Gene3D G3DSA:2.60.40.4150 25 170 8.4E-47 T 12-10-2018 IPR038706 Type VI secretion protein SciN-like superfamily VAPA_1c02450 8767e80ca0b5444d0e383de963f3c7e7 171 TIGRFAM TIGR03352 VI_chp_3: type VI secretion lipoprotein, VC_A0113 family 16 163 7.9E-33 T 12-10-2018 IPR017734 Type VI secretion system, lipoprotein SciN VAPA_1c02450 8767e80ca0b5444d0e383de963f3c7e7 171 Pfam PF12790 Type VI secretion lipoprotein, VasD, EvfM, TssJ, VC_A0113 20 146 5.4E-32 T 12-10-2018 IPR017734 Type VI secretion system, lipoprotein SciN VAPA_1c29330 676eee832ffa3b10e2b20cd4a1689674 158 Gene3D G3DSA:1.10.287.180 1 75 6.8E-29 T 12-10-2018 IPR036805 Transcription elongation factor, GreA/GreB, N-terminal domain superfamily GO:0003677|GO:0032784 VAPA_1c29330 676eee832ffa3b10e2b20cd4a1689674 158 Hamap MF_00105 Transcription elongation factor GreA [greA]. 2 156 31.256 T 12-10-2018 IPR028624 Transcription elongation factor GreA/GreB GO:0003677|GO:0032784|GO:0070063 VAPA_1c29330 676eee832ffa3b10e2b20cd4a1689674 158 SUPERFAMILY SSF54534 83 157 2.35E-23 T 12-10-2018 VAPA_1c29330 676eee832ffa3b10e2b20cd4a1689674 158 Gene3D G3DSA:3.10.50.30 76 158 2.3E-28 T 12-10-2018 IPR036953 Transcription elongation factor GreA/GreB, C-terminal domain superfamily GO:0003677|GO:0032784 VAPA_1c29330 676eee832ffa3b10e2b20cd4a1689674 158 TIGRFAM TIGR01462 greA: transcription elongation factor GreA 5 155 5.6E-54 T 12-10-2018 IPR006359 Transcription elongation factor GreA GO:0003677|GO:0032784 VAPA_1c29330 676eee832ffa3b10e2b20cd4a1689674 158 Pfam PF03449 Transcription elongation factor, N-terminal 4 74 2.3E-29 T 12-10-2018 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 VAPA_1c29330 676eee832ffa3b10e2b20cd4a1689674 158 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 83 157 5.3E-28 T 12-10-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 VAPA_1c29330 676eee832ffa3b10e2b20cd4a1689674 158 ProSitePatterns PS00829 Prokaryotic transcription elongation factors signature 1. 17 48 - T 12-10-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 VAPA_1c29330 676eee832ffa3b10e2b20cd4a1689674 158 PIRSF PIRSF006092 1 158 1.3E-50 T 12-10-2018 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 VAPA_1c29330 676eee832ffa3b10e2b20cd4a1689674 158 SUPERFAMILY SSF46557 3 77 2.88E-26 T 12-10-2018 IPR036805 Transcription elongation factor, GreA/GreB, N-terminal domain superfamily GO:0003677|GO:0032784 VAPA_1c44690 51c24882ffce0d562fe13449a8e53f3d 307 Gene3D G3DSA:1.10.10.10 5 94 3.1E-5 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c44690 51c24882ffce0d562fe13449a8e53f3d 307 Pfam PF13730 Helix-turn-helix domain 17 68 7.9E-8 T 12-10-2018 VAPA_1c44690 51c24882ffce0d562fe13449a8e53f3d 307 SUPERFAMILY SSF46785 39 80 9.6E-5 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c10930 72ede4940955e16319d14b8df8a9a5d9 317 Pfam PF08450 SMP-30/Gluconolaconase/LRE-like region 33 278 3.2E-78 T 12-10-2018 IPR013658 SMP-30/Gluconolactonase/LRE-like region VAPA_1c10930 72ede4940955e16319d14b8df8a9a5d9 317 SUPERFAMILY SSF63829 12 308 4.36E-63 T 12-10-2018 VAPA_1c10930 72ede4940955e16319d14b8df8a9a5d9 317 Gene3D G3DSA:2.120.10.30 22 312 2.4E-98 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like VAPA_1c10930 72ede4940955e16319d14b8df8a9a5d9 317 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 153 175 2.1E-38 T 12-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) VAPA_1c10930 72ede4940955e16319d14b8df8a9a5d9 317 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 259 277 2.1E-38 T 12-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) VAPA_1c10930 72ede4940955e16319d14b8df8a9a5d9 317 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 176 196 2.1E-38 T 12-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) VAPA_1c10930 72ede4940955e16319d14b8df8a9a5d9 317 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 112 133 2.1E-38 T 12-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) VAPA_1c10930 72ede4940955e16319d14b8df8a9a5d9 317 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 34 51 2.1E-38 T 12-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) VAPA_1c10930 72ede4940955e16319d14b8df8a9a5d9 317 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 216 233 2.1E-38 T 12-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) VAPA_1c08920 4ef8c1eaf4d6428c4edd25065ead27df 312 Pfam PF01156 Inosine-uridine preferring nucleoside hydrolase 4 302 5.3E-79 T 12-10-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain VAPA_1c08920 4ef8c1eaf4d6428c4edd25065ead27df 312 ProSitePatterns PS01247 Inosine-uridine preferring nucleoside hydrolase family signature. 7 17 - T 12-10-2018 IPR015910 Inosine/uridine-preferring nucleoside hydrolase, conserved site GO:0016799 VAPA_1c08920 4ef8c1eaf4d6428c4edd25065ead27df 312 SUPERFAMILY SSF53590 1 310 1.27E-90 T 12-10-2018 IPR036452 Ribonucleoside hydrolase-like VAPA_1c08920 4ef8c1eaf4d6428c4edd25065ead27df 312 Gene3D G3DSA:3.90.245.10 1 311 3.9E-97 T 12-10-2018 IPR036452 Ribonucleoside hydrolase-like VAPA_1c50640 3fd5b4d7f4b3cc38a8d9e0c7900f64fb 327 Pfam PF16881 N-terminal domain of lipoyl synthase of Radical_SAM family 36 80 1.2E-7 T 12-10-2018 IPR031691 Lipoyl synthase, N-terminal KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 VAPA_1c50640 3fd5b4d7f4b3cc38a8d9e0c7900f64fb 327 Hamap MF_00206 Lipoyl synthase [lipA]. 1 327 152.885 T 12-10-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 VAPA_1c50640 3fd5b4d7f4b3cc38a8d9e0c7900f64fb 327 PIRSF PIRSF005963 1 326 2.0E-127 T 12-10-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 VAPA_1c50640 3fd5b4d7f4b3cc38a8d9e0c7900f64fb 327 SUPERFAMILY SSF102114 59 323 1.31E-69 T 12-10-2018 VAPA_1c50640 3fd5b4d7f4b3cc38a8d9e0c7900f64fb 327 Gene3D G3DSA:3.20.20.70 85 301 1.3E-25 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 VAPA_1c50640 3fd5b4d7f4b3cc38a8d9e0c7900f64fb 327 TIGRFAM TIGR00510 lipA: lipoyl synthase 36 321 5.8E-128 T 12-10-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 VAPA_1c50640 3fd5b4d7f4b3cc38a8d9e0c7900f64fb 327 Pfam PF04055 Radical SAM superfamily 98 257 2.1E-16 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 VAPA_1c50640 3fd5b4d7f4b3cc38a8d9e0c7900f64fb 327 SMART SM00729 91 299 2.8E-22 T 12-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 VAPA_1c52720 5588fb62bacf6ace64d6757a29658c09 244 SMART SM00530 10 64 0.0018 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 VAPA_1c52720 5588fb62bacf6ace64d6757a29658c09 244 SUPERFAMILY SSF47413 2 67 1.81E-6 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 VAPA_1c52720 5588fb62bacf6ace64d6757a29658c09 244 Pfam PF13443 Cro/C1-type HTH DNA-binding domain 11 69 1.3E-7 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 VAPA_1c52720 5588fb62bacf6ace64d6757a29658c09 244 Gene3D G3DSA:1.10.260.40 2 70 1.2E-5 T 12-10-2018 VAPA_1c03900 222b4e8874b906dd37f6d61ba7f0b7ce 386 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 124 136 - T 12-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 VAPA_1c03900 222b4e8874b906dd37f6d61ba7f0b7ce 386 SUPERFAMILY SSF56645 2 241 7.85E-79 T 12-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 VAPA_1c03900 222b4e8874b906dd37f6d61ba7f0b7ce 386 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 336 355 - T 12-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 VAPA_1c03900 222b4e8874b906dd37f6d61ba7f0b7ce 386 SUPERFAMILY SSF47203 227 377 3.38E-43 T 12-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 VAPA_1c03900 222b4e8874b906dd37f6d61ba7f0b7ce 386 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 4 118 5.1E-30 T 12-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 VAPA_1c03900 222b4e8874b906dd37f6d61ba7f0b7ce 386 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 229 377 2.0E-43 T 12-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 VAPA_1c03900 222b4e8874b906dd37f6d61ba7f0b7ce 386 Gene3D G3DSA:2.40.110.10 121 233 2.8E-39 T 12-10-2018 VAPA_1c03900 222b4e8874b906dd37f6d61ba7f0b7ce 386 Gene3D G3DSA:1.20.140.10 234 378 1.0E-39 T 12-10-2018 VAPA_1c03900 222b4e8874b906dd37f6d61ba7f0b7ce 386 Gene3D G3DSA:1.10.540.10 1 120 2.5E-42 T 12-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 VAPA_1c03900 222b4e8874b906dd37f6d61ba7f0b7ce 386 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 122 217 1.1E-21 T 12-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 VAPA_1c03900 222b4e8874b906dd37f6d61ba7f0b7ce 386 PIRSF PIRSF016578 126 365 4.2E-12 T 12-10-2018 VAPA_1c03900 222b4e8874b906dd37f6d61ba7f0b7ce 386 PIRSF PIRSF016578 3 83 0.45 T 12-10-2018 VAPA_1c50370 1d41e53d278faf6ce19414dde7fab63c 390 Gene3D G3DSA:3.30.1330.160 275 390 1.7E-42 T 12-10-2018 VAPA_1c50370 1d41e53d278faf6ce19414dde7fab63c 390 Hamap MF_01989 Cyanuric acid amidohydrolase. 20 389 34.177 T 12-10-2018 IPR014086 Cyanuric acid hydrolase/Barbiturase GO:0016812 VAPA_1c50370 1d41e53d278faf6ce19414dde7fab63c 390 TIGRFAM TIGR02714 amido_AtzD_TrzD: ring-opening amidohydrolases 23 388 7.8E-116 T 12-10-2018 IPR014086 Cyanuric acid hydrolase/Barbiturase GO:0016812 VAPA_1c50370 1d41e53d278faf6ce19414dde7fab63c 390 Gene3D G3DSA:3.30.1330.170 19 125 1.7E-39 T 12-10-2018 VAPA_1c50370 1d41e53d278faf6ce19414dde7fab63c 390 Gene3D G3DSA:3.30.1330.180 130 274 9.5E-48 T 12-10-2018 VAPA_1c50370 1d41e53d278faf6ce19414dde7fab63c 390 Pfam PF09663 Amidohydrolase ring-opening protein (Amido_AtzD_TrzD) 24 387 2.0E-130 T 12-10-2018 IPR014086 Cyanuric acid hydrolase/Barbiturase GO:0016812 VAPA_1c20090 d8403708d9dc3b8e249749d70c1ce04f 139 Gene3D G3DSA:3.30.300.20 2 122 1.4E-19 T 12-10-2018 IPR015946 K homology domain-like, alpha/beta VAPA_1c20090 d8403708d9dc3b8e249749d70c1ce04f 139 Pfam PF02566 OsmC-like protein 35 127 7.7E-16 T 12-10-2018 IPR003718 OsmC/Ohr family VAPA_1c20090 d8403708d9dc3b8e249749d70c1ce04f 139 SUPERFAMILY SSF82784 3 128 6.54E-26 T 12-10-2018 IPR036102 OsmC/Ohr superfamily VAPA_1c00860 fc234142bc02f31078b40ae8ab41ba28 249 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 225 246 5.2E-8 T 12-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal VAPA_1c00860 fc234142bc02f31078b40ae8ab41ba28 249 SUPERFAMILY SSF52540 5 246 6.76E-57 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c00860 fc234142bc02f31078b40ae8ab41ba28 249 Gene3D G3DSA:3.40.50.300 4 249 1.6E-56 T 12-10-2018 VAPA_1c00860 fc234142bc02f31078b40ae8ab41ba28 249 SMART SM00382 30 224 5.5E-7 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c00860 fc234142bc02f31078b40ae8ab41ba28 249 Pfam PF00005 ABC transporter 22 176 1.7E-30 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_2c11770 0351a395e5e641954e5fc71cd47f1a8a 290 Gene3D G3DSA:3.20.20.60 1 290 3.0E-94 T 12-10-2018 VAPA_2c11770 0351a395e5e641954e5fc71cd47f1a8a 290 Pfam PF13714 Phosphoenolpyruvate phosphomutase 11 253 2.5E-70 T 12-10-2018 VAPA_2c11770 0351a395e5e641954e5fc71cd47f1a8a 290 TIGRFAM TIGR02321 Pphn_pyruv_hyd: phosphonopyruvate hydrolase 1 289 4.9E-177 T 12-10-2018 IPR012649 Phosphonopyruvate hydrolase KEGG: 00440+3.11.1.3 VAPA_2c11770 0351a395e5e641954e5fc71cd47f1a8a 290 SUPERFAMILY SSF51621 2 288 2.24E-75 T 12-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 VAPA_1c34670 6402e8de80d9281f13f761328c6af656 596 SUPERFAMILY SSF47203 281 459 8.22E-45 T 12-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 VAPA_1c34670 6402e8de80d9281f13f761328c6af656 596 SUPERFAMILY SSF56645 35 280 2.23E-53 T 12-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 VAPA_1c34670 6402e8de80d9281f13f761328c6af656 596 Pfam PF12418 Acyl-CoA dehydrogenase N terminal 2 32 3.7E-9 T 12-10-2018 IPR020953 Acyl-CoA dehydrogenase, N-terminal, bacteria VAPA_1c34670 6402e8de80d9281f13f761328c6af656 596 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 36 155 2.9E-10 T 12-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 VAPA_1c34670 6402e8de80d9281f13f761328c6af656 596 Pfam PF12806 Acetyl-CoA dehydrogenase C-terminal like 466 591 6.2E-26 T 12-10-2018 IPR025878 Acetyl-CoA dehydrogenase-like C-terminal domain VAPA_1c34670 6402e8de80d9281f13f761328c6af656 596 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 283 449 8.0E-27 T 12-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 VAPA_1c34670 6402e8de80d9281f13f761328c6af656 596 Gene3D G3DSA:2.40.110.10 159 287 5.6E-25 T 12-10-2018 VAPA_1c34670 6402e8de80d9281f13f761328c6af656 596 Gene3D G3DSA:1.20.140.10 288 454 1.3E-48 T 12-10-2018 VAPA_1c34670 6402e8de80d9281f13f761328c6af656 596 Gene3D G3DSA:1.10.540.10 33 157 3.2E-14 T 12-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 VAPA_1c34670 6402e8de80d9281f13f761328c6af656 596 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 161 269 2.8E-14 T 12-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 VAPA_1c26160 c92313ba020661f23047ca11b2c790b9 180 TIGRFAM TIGR00997 ispZ: intracellular septation protein A 1 176 1.9E-52 T 12-10-2018 IPR006008 Intracellular septation protein A GO:0016021 VAPA_1c26160 c92313ba020661f23047ca11b2c790b9 180 Hamap MF_00189 Probable intracellular septation protein A [yciB]. 1 175 17.562 T 12-10-2018 IPR006008 Intracellular septation protein A GO:0016021 VAPA_1c26160 c92313ba020661f23047ca11b2c790b9 180 Pfam PF04279 Intracellular septation protein A 1 173 7.5E-62 T 12-10-2018 IPR006008 Intracellular septation protein A GO:0016021 VAPA_2c01880 d5e7cc5433da36feaf077e3df6292ec6 236 Pfam PF03737 Aldolase/RraA 14 179 1.2E-32 T 12-10-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein VAPA_2c01880 d5e7cc5433da36feaf077e3df6292ec6 236 Gene3D G3DSA:3.50.30.100 2 201 2.8E-50 T 12-10-2018 VAPA_2c01880 d5e7cc5433da36feaf077e3df6292ec6 236 SUPERFAMILY SSF89562 10 190 2.09E-41 T 12-10-2018 IPR036704 Ribonuclease E inhibitor RraA/RraA-like superfamily VAPA_1c36410 a611f931d7cbcea1aaa53c6a71b883a0 268 TIGRFAM TIGR01469 cobA_cysG_Cterm: uroporphyrinogen-III C-methyltransferase 11 252 5.2E-82 T 12-10-2018 IPR006366 Uroporphyrin-III C-methyltransferase GO:0008168|GO:0019354 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 VAPA_1c36410 a611f931d7cbcea1aaa53c6a71b883a0 268 SUPERFAMILY SSF53790 10 252 2.49E-66 T 12-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 VAPA_1c36410 a611f931d7cbcea1aaa53c6a71b883a0 268 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 13 230 5.9E-46 T 12-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 VAPA_1c36410 a611f931d7cbcea1aaa53c6a71b883a0 268 ProSitePatterns PS00840 Uroporphyrin-III C-methyltransferase signature 2. 92 125 - T 12-10-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 VAPA_1c36410 a611f931d7cbcea1aaa53c6a71b883a0 268 ProSitePatterns PS00839 Uroporphyrin-III C-methyltransferase signature 1. 16 30 - T 12-10-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 VAPA_1c36410 a611f931d7cbcea1aaa53c6a71b883a0 268 Gene3D G3DSA:3.30.950.10 128 261 2.0E-36 T 12-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 VAPA_1c36410 a611f931d7cbcea1aaa53c6a71b883a0 268 Gene3D G3DSA:3.40.1010.10 10 127 1.0E-39 T 12-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 VAPA_2c10760 b1822b4cec9063223f599d6d421557ad 254 SMART SM00062 16 234 8.5E-18 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF VAPA_2c10760 b1822b4cec9063223f599d6d421557ad 254 Gene3D G3DSA:3.40.190.10 15 227 2.1E-20 T 12-10-2018 VAPA_2c10760 b1822b4cec9063223f599d6d421557ad 254 Gene3D G3DSA:3.40.190.10 103 195 2.1E-20 T 12-10-2018 VAPA_2c10760 b1822b4cec9063223f599d6d421557ad 254 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 35 232 3.9E-19 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF VAPA_2c10760 b1822b4cec9063223f599d6d421557ad 254 SUPERFAMILY SSF53850 32 233 4.89E-28 T 12-10-2018 VAPA_1c48950 7f057bfe6f9725761c1c2f275d410ffb 257 SUPERFAMILY SSF69593 6 245 2.22E-37 T 12-10-2018 VAPA_1c48950 7f057bfe6f9725761c1c2f275d410ffb 257 SMART SM00563 75 190 2.6E-27 T 12-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 VAPA_1c48950 7f057bfe6f9725761c1c2f275d410ffb 257 Pfam PF01553 Acyltransferase 59 187 8.8E-22 T 12-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 VAPA_1c23910 750a3115a0394db656fae330fa37ebd1 173 Pfam PF00583 Acetyltransferase (GNAT) family 32 138 2.2E-16 T 12-10-2018 IPR000182 GNAT domain VAPA_1c23910 750a3115a0394db656fae330fa37ebd1 173 Gene3D G3DSA:3.40.630.30 1 173 4.6E-53 T 12-10-2018 VAPA_1c23910 750a3115a0394db656fae330fa37ebd1 173 SUPERFAMILY SSF55729 7 165 5.83E-32 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase VAPA_1c18470 e9390940c97ae890d01621399abda7ef 377 SMART SM00116 238 286 9.6E-8 T 12-10-2018 IPR000644 CBS domain VAPA_1c18470 e9390940c97ae890d01621399abda7ef 377 SMART SM00116 322 370 7.2E-7 T 12-10-2018 IPR000644 CBS domain VAPA_1c18470 e9390940c97ae890d01621399abda7ef 377 Gene3D G3DSA:3.10.580.10 159 290 2.0E-15 T 12-10-2018 VAPA_1c18470 e9390940c97ae890d01621399abda7ef 377 SUPERFAMILY SSF54631 219 371 2.66E-32 T 12-10-2018 VAPA_1c18470 e9390940c97ae890d01621399abda7ef 377 Gene3D G3DSA:3.10.580.10 292 372 5.2E-14 T 12-10-2018 VAPA_1c18470 e9390940c97ae890d01621399abda7ef 377 Pfam PF04982 HPP family 57 173 1.2E-37 T 12-10-2018 IPR007065 HPP VAPA_1c18470 e9390940c97ae890d01621399abda7ef 377 Pfam PF00571 CBS domain 315 369 3.5E-10 T 12-10-2018 IPR000644 CBS domain VAPA_1c18470 e9390940c97ae890d01621399abda7ef 377 Pfam PF00571 CBS domain 232 285 6.1E-10 T 12-10-2018 IPR000644 CBS domain VAPA_2c00850 256aa31ea93de307eda86e904a1c8f61 123 Gene3D G3DSA:3.10.180.10 6 115 1.1E-12 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase VAPA_2c00850 256aa31ea93de307eda86e904a1c8f61 123 SUPERFAMILY SSF54593 5 118 2.28E-14 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase VAPA_1c04980 92e18214e300015f6eb7766ce6344940 174 SUPERFAMILY SSF69118 16 165 3.12E-19 T 12-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 VAPA_1c04980 92e18214e300015f6eb7766ce6344940 174 Gene3D G3DSA:1.20.1290.10 56 174 2.4E-12 T 12-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 VAPA_1c07190 b9ff90e997a439ee05d09e3ab4cea10e 146 SUPERFAMILY SSF47413 82 135 1.07E-8 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 VAPA_1c07190 b9ff90e997a439ee05d09e3ab4cea10e 146 SMART SM00530 84 139 1.7E-4 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 VAPA_1c07190 b9ff90e997a439ee05d09e3ab4cea10e 146 Gene3D G3DSA:1.10.260.40 80 141 2.3E-10 T 12-10-2018 VAPA_1c07190 b9ff90e997a439ee05d09e3ab4cea10e 146 Pfam PF13560 Helix-turn-helix domain 84 133 2.2E-7 T 12-10-2018 VAPA_1c47750 ba5e01cdaa018cc485dc75cfdafea5f1 352 Pfam PF01207 Dihydrouridine synthase (Dus) 16 317 1.7E-101 T 12-10-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 VAPA_1c47750 ba5e01cdaa018cc485dc75cfdafea5f1 352 Gene3D G3DSA:3.20.20.70 8 254 1.2E-77 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 VAPA_1c47750 ba5e01cdaa018cc485dc75cfdafea5f1 352 Gene3D G3DSA:1.10.1200.80 257 330 2.0E-9 T 12-10-2018 IPR024036 tRNA-dihydrouridine synthase, putative, C-terminal GO:0016491|GO:0055114 VAPA_1c47750 ba5e01cdaa018cc485dc75cfdafea5f1 352 SUPERFAMILY SSF51395 12 323 6.41E-90 T 12-10-2018 VAPA_1c47750 ba5e01cdaa018cc485dc75cfdafea5f1 352 TIGRFAM TIGR00737 nifR3_yhdG: putative TIM-barrel protein, nifR3 family 5 322 3.8E-116 T 12-10-2018 IPR004652 tRNA-dihydrouridine synthase, TIM-barrel, NifR3 GO:0008033|GO:0016491|GO:0050660|GO:0055114 VAPA_1c47750 ba5e01cdaa018cc485dc75cfdafea5f1 352 ProSitePatterns PS01136 Uncharacterized protein family UPF0034 signature. 96 114 - T 12-10-2018 IPR018517 tRNA-dihydrouridine synthase, conserved site GO:0008033|GO:0017150|GO:0050660|GO:0055114 VAPA_1c47750 ba5e01cdaa018cc485dc75cfdafea5f1 352 PIRSF PIRSF006621 2 328 1.0E-104 T 12-10-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 VAPA_1c47750 ba5e01cdaa018cc485dc75cfdafea5f1 352 Hamap MF_02042 tRNA-dihydrouridine synthase B [dusB]. 3 326 48.635 T 12-10-2018 IPR032887 tRNA-dihydrouridine synthase B GO:0002943|GO:0017150 VAPA_1c54870 945c3b9afc7d35cc3ba746d89fb3e401 364 Gene3D G3DSA:3.90.1200.10 118 356 4.1E-70 T 12-10-2018 VAPA_1c54870 945c3b9afc7d35cc3ba746d89fb3e401 364 Gene3D G3DSA:3.30.200.20 22 117 2.2E-20 T 12-10-2018 VAPA_1c54870 945c3b9afc7d35cc3ba746d89fb3e401 364 SUPERFAMILY SSF56112 45 332 7.14E-53 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily VAPA_1c54870 945c3b9afc7d35cc3ba746d89fb3e401 364 Pfam PF01636 Phosphotransferase enzyme family 47 275 1.8E-29 T 12-10-2018 IPR002575 Aminoglycoside phosphotransferase VAPA_2c02080 8f9a69600dbce8bf1fce1cc1297fecfe 89 Gene3D G3DSA:3.40.1580.10 2 88 7.2E-14 T 12-10-2018 IPR037883 Knr4/Smi1-like domain superfamily VAPA_2c02080 8f9a69600dbce8bf1fce1cc1297fecfe 89 SUPERFAMILY SSF160631 12 85 8.24E-5 T 12-10-2018 VAPA_1c27400 838b984d9bc0eb157deb7784b8a858c1 349 SUPERFAMILY SSF51430 1 319 6.29E-104 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily VAPA_1c27400 838b984d9bc0eb157deb7784b8a858c1 349 Gene3D G3DSA:3.20.20.100 1 343 2.2E-126 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily VAPA_1c27400 838b984d9bc0eb157deb7784b8a858c1 349 Pfam PF00248 Aldo/keto reductase family 15 319 2.7E-81 T 12-10-2018 IPR023210 NADP-dependent oxidoreductase domain VAPA_1c54120 3426285e1820e62c2ff882d13218e628 307 SUPERFAMILY SSF53850 96 298 1.99E-34 T 12-10-2018 VAPA_1c54120 3426285e1820e62c2ff882d13218e628 307 Pfam PF03466 LysR substrate binding domain 95 294 1.4E-33 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_1c54120 3426285e1820e62c2ff882d13218e628 307 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 36 46 2.7E-9 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c54120 3426285e1820e62c2ff882d13218e628 307 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 25 36 2.7E-9 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c54120 3426285e1820e62c2ff882d13218e628 307 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 46 57 2.7E-9 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c54120 3426285e1820e62c2ff882d13218e628 307 SUPERFAMILY SSF46785 6 85 5.53E-23 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c54120 3426285e1820e62c2ff882d13218e628 307 Gene3D G3DSA:1.10.10.10 9 93 1.4E-23 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c54120 3426285e1820e62c2ff882d13218e628 307 Gene3D G3DSA:3.40.190.10 106 292 8.0E-49 T 12-10-2018 VAPA_1c54120 3426285e1820e62c2ff882d13218e628 307 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 10 69 1.4E-21 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c54120 3426285e1820e62c2ff882d13218e628 307 Gene3D G3DSA:3.40.190.10 166 264 8.0E-49 T 12-10-2018 VAPA_1c12720 9bfd32a0bcf1e8f7b61c2303abfbae91 198 PRINTS PR00127 Clp protease catalytic subunit P signature 111 130 2.1E-20 T 12-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 VAPA_1c12720 9bfd32a0bcf1e8f7b61c2303abfbae91 198 PRINTS PR00127 Clp protease catalytic subunit P signature 59 79 2.1E-20 T 12-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 VAPA_1c12720 9bfd32a0bcf1e8f7b61c2303abfbae91 198 PRINTS PR00127 Clp protease catalytic subunit P signature 168 187 2.1E-20 T 12-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 VAPA_1c12720 9bfd32a0bcf1e8f7b61c2303abfbae91 198 SUPERFAMILY SSF52096 22 193 2.32E-47 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily VAPA_1c12720 9bfd32a0bcf1e8f7b61c2303abfbae91 198 ProSitePatterns PS00382 Endopeptidase Clp histidine active site. 112 125 - T 12-10-2018 IPR033135 ClpP, histidine active site VAPA_1c12720 9bfd32a0bcf1e8f7b61c2303abfbae91 198 Pfam PF00574 Clp protease 21 192 2.1E-55 T 12-10-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA VAPA_1c12720 9bfd32a0bcf1e8f7b61c2303abfbae91 198 Gene3D G3DSA:3.90.226.10 10 197 2.3E-54 T 12-10-2018 VAPA_2c08570 aebe5e420f0065aefbbf5d4848f9b209 310 TIGRFAM TIGR02108 PQQ_syn_pqqB: coenzyme PQQ biosynthesis protein B 2 310 9.5E-116 T 12-10-2018 IPR011842 Coenzyme PQQ biosynthesis protein B VAPA_2c08570 aebe5e420f0065aefbbf5d4848f9b209 310 Pfam PF12706 Beta-lactamase superfamily domain 51 277 6.5E-44 T 12-10-2018 IPR001279 Metallo-beta-lactamase VAPA_2c08570 aebe5e420f0065aefbbf5d4848f9b209 310 SUPERFAMILY SSF56281 1 310 5.47E-58 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like VAPA_2c08570 aebe5e420f0065aefbbf5d4848f9b209 310 Hamap MF_00653 Coenzyme PQQ synthesis protein B [pqqB]. 1 310 154.343 T 12-10-2018 IPR011842 Coenzyme PQQ biosynthesis protein B VAPA_2c08570 aebe5e420f0065aefbbf5d4848f9b209 310 Gene3D G3DSA:3.60.15.10 1 310 8.2E-90 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like VAPA_1c54040 342378d36a296a5f734862fbd25af421 161 Pfam PF12802 MarR family 56 112 7.5E-8 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 VAPA_1c54040 342378d36a296a5f734862fbd25af421 161 SUPERFAMILY SSF46785 46 146 1.15E-16 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c54040 342378d36a296a5f734862fbd25af421 161 Gene3D G3DSA:1.10.10.10 12 155 1.4E-22 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c37500 d8f750616fa5fbadccdff45bcc567707 119 Pfam PF02482 Sigma 54 modulation protein / S30EA ribosomal protein 7 96 3.3E-7 T 12-10-2018 IPR003489 Ribosome hibernation promoting factor/RaiA GO:0044238 VAPA_1c37500 d8f750616fa5fbadccdff45bcc567707 119 Gene3D G3DSA:3.30.160.100 1 104 3.4E-6 T 12-10-2018 IPR036567 Ribosome hibernation promotion factor-like VAPA_1c37500 d8f750616fa5fbadccdff45bcc567707 119 SUPERFAMILY SSF69754 8 110 4.05E-10 T 12-10-2018 IPR036567 Ribosome hibernation promotion factor-like VAPA_1c04470 c035469b3de8a3f7cc229d981ef04b05 283 PIRSF PIRSF038992 1 280 5.6E-67 T 12-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 VAPA_1c04470 c035469b3de8a3f7cc229d981ef04b05 283 SMART SM01133 18 250 1.1E-6 T 12-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 VAPA_1c04470 c035469b3de8a3f7cc229d981ef04b05 283 SUPERFAMILY SSF51569 5 265 5.49E-54 T 12-10-2018 VAPA_1c04470 c035469b3de8a3f7cc229d981ef04b05 283 Pfam PF01791 DeoC/LacD family aldolase 19 250 7.2E-45 T 12-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 VAPA_1c04470 c035469b3de8a3f7cc229d981ef04b05 283 Gene3D G3DSA:3.20.20.70 2 280 4.9E-59 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 VAPA_1c31980 2cccc886d1c1fe7bbc999c5a6ca630cd 360 Gene3D G3DSA:3.90.660.10 60 322 2.3E-90 T 12-10-2018 VAPA_1c31980 2cccc886d1c1fe7bbc999c5a6ca630cd 360 SUPERFAMILY SSF51905 20 359 6.62E-33 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c31980 2cccc886d1c1fe7bbc999c5a6ca630cd 360 Pfam PF13450 NAD(P)-binding Rossmann-like domain 24 77 5.3E-13 T 12-10-2018 VAPA_1c31980 2cccc886d1c1fe7bbc999c5a6ca630cd 360 Gene3D G3DSA:3.50.50.60 23 356 2.3E-90 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c31980 2cccc886d1c1fe7bbc999c5a6ca630cd 360 PRINTS PR00419 Adrenodoxin reductase family signature 44 57 9.7E-6 T 12-10-2018 VAPA_1c31980 2cccc886d1c1fe7bbc999c5a6ca630cd 360 PRINTS PR00419 Adrenodoxin reductase family signature 21 43 9.7E-6 T 12-10-2018 VAPA_1c31980 2cccc886d1c1fe7bbc999c5a6ca630cd 360 Pfam PF01593 Flavin containing amine oxidoreductase 118 359 1.3E-10 T 12-10-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 VAPA_1c31040 ec5159c76df14da236476708c687f3f3 331 TIGRFAM TIGR03866 PQQ_ABC_repeats: PQQ-dependent catabolism-associated beta-propeller protein 28 330 6.9E-95 T 12-10-2018 IPR022456 PQQ-dependent catabolism-associated beta-propeller protein VAPA_1c31040 ec5159c76df14da236476708c687f3f3 331 SUPERFAMILY SSF50974 14 330 1.86E-66 T 12-10-2018 IPR011045 Nitrous oxide reductase, N-terminal Reactome: R-HSA-114608 VAPA_1c31040 ec5159c76df14da236476708c687f3f3 331 Gene3D G3DSA:2.130.10.10 235 330 1.6E-16 T 12-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 VAPA_1c31040 ec5159c76df14da236476708c687f3f3 331 Pfam PF10282 Lactonase, 7-bladed beta-propeller 184 309 1.8E-5 T 12-10-2018 IPR019405 Lactonase, 7-bladed beta propeller VAPA_1c31040 ec5159c76df14da236476708c687f3f3 331 Gene3D G3DSA:2.130.10.10 32 234 6.6E-54 T 12-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 VAPA_1c31040 ec5159c76df14da236476708c687f3f3 331 TIGRFAM TIGR02276 beta_rpt_yvtn: 40-residue YVTN family beta-propeller repeat 292 329 1.0E-10 T 12-10-2018 IPR011964 YVTN beta-propeller repeat VAPA_1c31040 ec5159c76df14da236476708c687f3f3 331 TIGRFAM TIGR02276 beta_rpt_yvtn: 40-residue YVTN family beta-propeller repeat 156 195 4.2E-10 T 12-10-2018 IPR011964 YVTN beta-propeller repeat VAPA_1c31040 ec5159c76df14da236476708c687f3f3 331 TIGRFAM TIGR02276 beta_rpt_yvtn: 40-residue YVTN family beta-propeller repeat 113 154 1.8E-7 T 12-10-2018 IPR011964 YVTN beta-propeller repeat VAPA_1c13140 a5d090c6748f58cbcb496e5876463afa 254 SUPERFAMILY SSF53335 10 246 3.18E-37 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase VAPA_1c13140 a5d090c6748f58cbcb496e5876463afa 254 Gene3D G3DSA:3.40.50.150 14 249 1.5E-40 T 12-10-2018 VAPA_1c11340 bb84fb416e0e59c0047f1b9a94a2a847 154 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 12 33 1.6E-6 T 12-10-2018 IPR012902 Prokaryotic N-terminal methylation site VAPA_1c11340 bb84fb416e0e59c0047f1b9a94a2a847 154 SUPERFAMILY SSF54523 14 82 1.33E-10 T 12-10-2018 VAPA_1c11340 bb84fb416e0e59c0047f1b9a94a2a847 154 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 12 32 - T 12-10-2018 IPR012902 Prokaryotic N-terminal methylation site VAPA_1c11340 bb84fb416e0e59c0047f1b9a94a2a847 154 Gene3D G3DSA:3.30.700.10 14 138 4.1E-6 T 12-10-2018 VAPA_1c11340 bb84fb416e0e59c0047f1b9a94a2a847 154 TIGRFAM TIGR01708 typeII_sec_gspH: type II secretion system protein H 9 75 6.6E-15 T 12-10-2018 IPR002416 Type II secretion system protein H GO:0008565|GO:0015627|GO:0015628 VAPA_1c11340 bb84fb416e0e59c0047f1b9a94a2a847 154 Pfam PF07963 Prokaryotic N-terminal methylation motif 9 33 8.9E-8 T 12-10-2018 IPR012902 Prokaryotic N-terminal methylation site VAPA_1c01840 d21142dac8a9340e7912bb1466d321b4 456 Gene3D G3DSA:3.90.226.10 189 405 2.3E-71 T 12-10-2018 VAPA_1c01840 d21142dac8a9340e7912bb1466d321b4 456 SUPERFAMILY SSF52096 75 401 1.03E-30 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily VAPA_1c01840 d21142dac8a9340e7912bb1466d321b4 456 Gene3D G3DSA:3.30.750.170 35 374 2.3E-71 T 12-10-2018 VAPA_1c01840 d21142dac8a9340e7912bb1466d321b4 456 Gene3D G3DSA:2.30.42.10 86 188 2.3E-71 T 12-10-2018 VAPA_1c01840 d21142dac8a9340e7912bb1466d321b4 456 SMART SM00228 97 174 6.3E-4 T 12-10-2018 IPR001478 PDZ domain GO:0005515 VAPA_1c01840 d21142dac8a9340e7912bb1466d321b4 456 Pfam PF03572 Peptidase family S41 204 349 2.4E-13 T 12-10-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 VAPA_1c01840 d21142dac8a9340e7912bb1466d321b4 456 SUPERFAMILY SSF50156 95 164 1.03E-7 T 12-10-2018 IPR036034 PDZ superfamily GO:0005515 VAPA_1c09180 b33cfc5b72fb3ac84d67624e67b6c387 314 Pfam PF03466 LysR substrate binding domain 87 293 1.3E-42 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_1c09180 b33cfc5b72fb3ac84d67624e67b6c387 314 SUPERFAMILY SSF46785 6 111 6.63E-19 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c09180 b33cfc5b72fb3ac84d67624e67b6c387 314 Gene3D G3DSA:3.40.190.290 91 302 1.0E-43 T 12-10-2018 VAPA_1c09180 b33cfc5b72fb3ac84d67624e67b6c387 314 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 62 3.8E-17 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c09180 b33cfc5b72fb3ac84d67624e67b6c387 314 Gene3D G3DSA:1.10.10.10 3 84 1.4E-20 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c09180 b33cfc5b72fb3ac84d67624e67b6c387 314 SUPERFAMILY SSF53850 86 298 6.37E-43 T 12-10-2018 VAPA_1c36490 86e4b47b917e47e51ad84ee03365da6c 261 SUPERFAMILY SSF54001 56 227 1.77E-27 T 12-10-2018 IPR038765 Papain-like cysteine peptidase superfamily VAPA_1c36490 86e4b47b917e47e51ad84ee03365da6c 261 Gene3D G3DSA:3.90.1720.10 53 233 6.2E-9 T 12-10-2018 VAPA_1c53140 452c08fbe7b00175d9cd024ec68f826c 252 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 28 246 6.9E-65 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF VAPA_1c53140 452c08fbe7b00175d9cd024ec68f826c 252 SUPERFAMILY SSF53850 6 248 1.26E-67 T 12-10-2018 VAPA_1c53140 452c08fbe7b00175d9cd024ec68f826c 252 SMART SM00079 27 247 2.8E-4 T 12-10-2018 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 VAPA_1c53140 452c08fbe7b00175d9cd024ec68f826c 252 Gene3D G3DSA:3.40.190.10 112 207 1.6E-67 T 12-10-2018 VAPA_1c53140 452c08fbe7b00175d9cd024ec68f826c 252 SMART SM00062 27 248 1.1E-65 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF VAPA_1c53140 452c08fbe7b00175d9cd024ec68f826c 252 Gene3D G3DSA:3.40.190.10 30 244 1.6E-67 T 12-10-2018 VAPA_1c02150 ceeae389cee62253d4a075ce8acedac9 300 Gene3D G3DSA:3.10.520.10 55 236 2.0E-37 T 12-10-2018 VAPA_1c02150 ceeae389cee62253d4a075ce8acedac9 300 SUPERFAMILY SSF143631 7 242 1.7E-61 T 12-10-2018 IPR003374 ApbE-like superfamily VAPA_1c02150 ceeae389cee62253d4a075ce8acedac9 300 PIRSF PIRSF006421 1 273 3.5E-61 T 12-10-2018 IPR007183 Uncharacterised protein family UPF0280 VAPA_1c38890 65b7b3b913be3de802f6779c8024276e 500 Hamap MF_01931 Amidophosphoribosyltransferase [purF]. 1 463 44.7 T 12-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 VAPA_1c38890 65b7b3b913be3de802f6779c8024276e 500 SUPERFAMILY SSF56235 2 256 2.23E-64 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal VAPA_1c38890 65b7b3b913be3de802f6779c8024276e 500 Gene3D G3DSA:3.60.20.10 2 465 1.6E-146 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal VAPA_1c38890 65b7b3b913be3de802f6779c8024276e 500 PIRSF PIRSF000485 1 479 5.5E-156 T 12-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 VAPA_1c38890 65b7b3b913be3de802f6779c8024276e 500 Pfam PF13537 Glutamine amidotransferase domain 82 212 1.3E-19 T 12-10-2018 IPR017932 Glutamine amidotransferase type 2 domain VAPA_1c38890 65b7b3b913be3de802f6779c8024276e 500 TIGRFAM TIGR01134 purF: amidophosphoribosyltransferase 2 463 2.1E-153 T 12-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 VAPA_1c38890 65b7b3b913be3de802f6779c8024276e 500 Gene3D G3DSA:3.40.50.2020 274 443 1.6E-146 T 12-10-2018 VAPA_1c38890 65b7b3b913be3de802f6779c8024276e 500 Pfam PF00156 Phosphoribosyl transferase domain 272 393 2.0E-10 T 12-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 VAPA_1c38890 65b7b3b913be3de802f6779c8024276e 500 SUPERFAMILY SSF53271 249 477 6.42E-72 T 12-10-2018 IPR029057 Phosphoribosyltransferase-like VAPA_2c02170 dfb87f3d13a63f1f7107efe5b1a3af27 388 Pfam PF13378 Enolase C-terminal domain-like 167 376 3.3E-37 T 12-10-2018 IPR029065 Enolase C-terminal domain-like VAPA_2c02170 dfb87f3d13a63f1f7107efe5b1a3af27 388 SUPERFAMILY SSF51604 123 384 5.8E-52 T 12-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily VAPA_2c02170 dfb87f3d13a63f1f7107efe5b1a3af27 388 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 87 134 2.1E-4 T 12-10-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain VAPA_2c02170 dfb87f3d13a63f1f7107efe5b1a3af27 388 Gene3D G3DSA:3.30.390.10 1 127 1.3E-67 T 12-10-2018 IPR029017 Enolase-like, N-terminal VAPA_2c02170 dfb87f3d13a63f1f7107efe5b1a3af27 388 SMART SM00922 162 259 3.7E-12 T 12-10-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal VAPA_2c02170 dfb87f3d13a63f1f7107efe5b1a3af27 388 Gene3D G3DSA:3.20.20.120 128 388 4.0E-64 T 12-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily VAPA_2c02170 dfb87f3d13a63f1f7107efe5b1a3af27 388 SUPERFAMILY SSF54826 1 138 2.77E-29 T 12-10-2018 VAPA_1c40530 8ea9e5b5dc74b8f2db835767a9397bb8 592 Gene3D G3DSA:3.30.70.360 391 504 6.7E-122 T 12-10-2018 VAPA_1c40530 8ea9e5b5dc74b8f2db835767a9397bb8 592 SUPERFAMILY SSF53187 182 587 9.71E-74 T 12-10-2018 VAPA_1c40530 8ea9e5b5dc74b8f2db835767a9397bb8 592 SUPERFAMILY SSF158694 4 172 1.7E-49 T 12-10-2018 IPR036778 Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase superfamily KEGG: 00230+4.1.1.97|MetaCyc: PWY-5691|MetaCyc: PWY-7394|MetaCyc: PWY-7849 VAPA_1c40530 8ea9e5b5dc74b8f2db835767a9397bb8 592 SUPERFAMILY SSF55031 393 503 6.13E-24 T 12-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain VAPA_1c40530 8ea9e5b5dc74b8f2db835767a9397bb8 592 TIGRFAM TIGR03164 UHCUDC: OHCU decarboxylase 18 171 7.4E-52 T 12-10-2018 IPR017580 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase, type 1 GO:0019428 KEGG: 00230+4.1.1.97|MetaCyc: PWY-5691|MetaCyc: PWY-7394|MetaCyc: PWY-7849 VAPA_1c40530 8ea9e5b5dc74b8f2db835767a9397bb8 592 Pfam PF09349 OHCU decarboxylase 9 169 1.5E-41 T 12-10-2018 IPR018020 Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase KEGG: 00230+4.1.1.97|MetaCyc: PWY-5691|MetaCyc: PWY-7394|MetaCyc: PWY-7849 VAPA_1c40530 8ea9e5b5dc74b8f2db835767a9397bb8 592 Gene3D G3DSA:1.10.3330.10 3 179 2.8E-56 T 12-10-2018 IPR036778 Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase superfamily KEGG: 00230+4.1.1.97|MetaCyc: PWY-5691|MetaCyc: PWY-7394|MetaCyc: PWY-7849 VAPA_1c40530 8ea9e5b5dc74b8f2db835767a9397bb8 592 TIGRFAM TIGR01879 hydantase: amidase, hydantoinase/carbamoylase family 196 581 2.9E-98 T 12-10-2018 IPR010158 Amidase, carbamoylase-type GO:0016813 VAPA_1c40530 8ea9e5b5dc74b8f2db835767a9397bb8 592 Gene3D G3DSA:3.40.630.10 199 579 6.7E-122 T 12-10-2018 VAPA_1c40530 8ea9e5b5dc74b8f2db835767a9397bb8 592 Pfam PF01546 Peptidase family M20/M25/M40 255 585 2.8E-23 T 12-10-2018 IPR002933 Peptidase M20 GO:0016787 VAPA_1c32090 e6fdd28b1861ba980cd85f359beffd9b 321 Gene3D G3DSA:3.40.190.150 27 307 7.5E-101 T 12-10-2018 VAPA_1c32090 e6fdd28b1861ba980cd85f359beffd9b 321 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 46 305 5.1E-72 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c32090 e6fdd28b1861ba980cd85f359beffd9b 321 Gene3D G3DSA:3.40.190.10 123 246 7.5E-101 T 12-10-2018 VAPA_1c32090 e6fdd28b1861ba980cd85f359beffd9b 321 SUPERFAMILY SSF53850 102 281 1.41E-13 T 12-10-2018 VAPA_1c32090 e6fdd28b1861ba980cd85f359beffd9b 321 PIRSF PIRSF017082 1 321 3.1E-89 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c18960 5d620b75af5a9f9de4571691b49d4946 184 Pfam PF01292 Prokaryotic cytochrome b561 12 173 5.5E-20 T 12-10-2018 IPR011577 Cytochrome b561, bacterial/Ni-hydrogenase GO:0009055|GO:0016021 VAPA_1c18960 5d620b75af5a9f9de4571691b49d4946 184 Gene3D G3DSA:1.20.950.20 3 160 6.6E-10 T 12-10-2018 VAPA_1c18960 5d620b75af5a9f9de4571691b49d4946 184 SUPERFAMILY SSF81342 8 177 1.33E-30 T 12-10-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 VAPA_1c32440 b3255d24ac1d75de25789d51534e1f0c 739 Pfam PF01433 Peptidase family M1 domain 315 553 2.5E-52 T 12-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 VAPA_1c32440 b3255d24ac1d75de25789d51534e1f0c 739 Gene3D G3DSA:1.10.390.60 310 559 7.0E-63 T 12-10-2018 VAPA_1c32440 b3255d24ac1d75de25789d51534e1f0c 739 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 405 420 1.2E-18 T 12-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 VAPA_1c32440 b3255d24ac1d75de25789d51534e1f0c 739 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 424 436 1.2E-18 T 12-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 VAPA_1c32440 b3255d24ac1d75de25789d51534e1f0c 739 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 372 382 1.2E-18 T 12-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 VAPA_1c32440 b3255d24ac1d75de25789d51534e1f0c 739 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 234 249 1.2E-18 T 12-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 VAPA_1c32440 b3255d24ac1d75de25789d51534e1f0c 739 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 282 297 1.2E-18 T 12-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 VAPA_1c32440 b3255d24ac1d75de25789d51534e1f0c 739 SUPERFAMILY SSF55486 313 566 8.14E-60 T 12-10-2018 VAPA_1c32440 b3255d24ac1d75de25789d51534e1f0c 739 Gene3D G3DSA:2.60.40.1730 70 299 5.9E-40 T 12-10-2018 VAPA_1c32440 b3255d24ac1d75de25789d51534e1f0c 739 SUPERFAMILY SSF63737 75 298 5.62E-30 T 12-10-2018 VAPA_1c33310 9a22d423d9a7bb8ad15f995e5eec2578 303 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 4.5E-16 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c33310 9a22d423d9a7bb8ad15f995e5eec2578 303 Pfam PF03466 LysR substrate binding domain 90 292 2.4E-42 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_1c33310 9a22d423d9a7bb8ad15f995e5eec2578 303 SUPERFAMILY SSF46785 4 111 8.02E-20 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c33310 9a22d423d9a7bb8ad15f995e5eec2578 303 Gene3D G3DSA:1.10.10.10 3 88 7.9E-26 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c33310 9a22d423d9a7bb8ad15f995e5eec2578 303 Gene3D G3DSA:3.40.190.290 92 294 1.4E-60 T 12-10-2018 VAPA_1c33310 9a22d423d9a7bb8ad15f995e5eec2578 303 SUPERFAMILY SSF53850 90 297 4.81E-44 T 12-10-2018 VAPA_1c36920 be3f27031739d81515a6c1002fdb6476 174 Pfam PF01047 MarR family 37 95 2.0E-10 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 VAPA_1c36920 be3f27031739d81515a6c1002fdb6476 174 SUPERFAMILY SSF46785 7 148 1.89E-25 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c36920 be3f27031739d81515a6c1002fdb6476 174 SMART SM00347 32 130 1.1E-13 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 VAPA_1c36920 be3f27031739d81515a6c1002fdb6476 174 PRINTS PR00598 Bacterial regulatory protein MarR family signature 120 140 3.6E-6 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 VAPA_1c36920 be3f27031739d81515a6c1002fdb6476 174 PRINTS PR00598 Bacterial regulatory protein MarR family signature 71 86 3.6E-6 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 VAPA_1c36920 be3f27031739d81515a6c1002fdb6476 174 PRINTS PR00598 Bacterial regulatory protein MarR family signature 90 106 3.6E-6 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 VAPA_1c36920 be3f27031739d81515a6c1002fdb6476 174 PRINTS PR00598 Bacterial regulatory protein MarR family signature 54 70 3.6E-6 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 VAPA_1c36920 be3f27031739d81515a6c1002fdb6476 174 Gene3D G3DSA:1.10.10.10 2 146 1.3E-28 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c41180 f3ed43feefa333d681be5084823a7192 174 Gene3D G3DSA:3.40.140.10 8 170 3.6E-37 T 12-10-2018 VAPA_1c41180 f3ed43feefa333d681be5084823a7192 174 SUPERFAMILY SSF53927 18 169 2.84E-35 T 12-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 VAPA_1c41180 f3ed43feefa333d681be5084823a7192 174 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 20 119 1.7E-19 T 12-10-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain VAPA_1c41180 f3ed43feefa333d681be5084823a7192 174 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 70 108 - T 12-10-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 VAPA_1c11650 8e6859b88a699111131c5a1a2ab9a82d 285 Gene3D G3DSA:1.10.3720.10 45 283 2.4E-55 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c11650 8e6859b88a699111131c5a1a2ab9a82d 285 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 80 283 3.5E-17 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 VAPA_1c11650 8e6859b88a699111131c5a1a2ab9a82d 285 SUPERFAMILY SSF160964 2 37 3.92E-5 T 12-10-2018 VAPA_1c11650 8e6859b88a699111131c5a1a2ab9a82d 285 SUPERFAMILY SSF161098 50 274 6.15E-52 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c50790 e669ca62a5fe08703a5d4a5eefe66d7d 84 PRINTS PR00107 Phosphocarrier protein signature 48 65 8.6E-12 T 12-10-2018 IPR000032 Phosphocarrier protein HPr-like VAPA_1c50790 e669ca62a5fe08703a5d4a5eefe66d7d 84 PRINTS PR00107 Phosphocarrier protein signature 33 48 8.6E-12 T 12-10-2018 IPR000032 Phosphocarrier protein HPr-like VAPA_1c50790 e669ca62a5fe08703a5d4a5eefe66d7d 84 PRINTS PR00107 Phosphocarrier protein signature 8 24 8.6E-12 T 12-10-2018 IPR000032 Phosphocarrier protein HPr-like VAPA_1c50790 e669ca62a5fe08703a5d4a5eefe66d7d 84 ProSitePatterns PS00589 PTS HPR domain serine phosphorylation site signature. 34 49 - T 12-10-2018 IPR002114 Phosphotransferase system, HPr serine phosphorylation site VAPA_1c50790 e669ca62a5fe08703a5d4a5eefe66d7d 84 Pfam PF00381 PTS HPr component phosphorylation site 1 77 4.5E-25 T 12-10-2018 IPR000032 Phosphocarrier protein HPr-like VAPA_1c50790 e669ca62a5fe08703a5d4a5eefe66d7d 84 Gene3D G3DSA:3.30.1340.10 1 83 7.0E-29 T 12-10-2018 IPR035895 HPr-like superfamily VAPA_1c50790 e669ca62a5fe08703a5d4a5eefe66d7d 84 TIGRFAM TIGR01003 PTS_HPr_family: phosphocarrier, HPr family 1 77 1.5E-28 T 12-10-2018 IPR000032 Phosphocarrier protein HPr-like VAPA_1c50790 e669ca62a5fe08703a5d4a5eefe66d7d 84 ProSitePatterns PS00369 PTS HPR domain histidine phosphorylation site signature. 8 15 - T 12-10-2018 IPR001020 Phosphotransferase system, HPr histidine phosphorylation site VAPA_1c50790 e669ca62a5fe08703a5d4a5eefe66d7d 84 SUPERFAMILY SSF55594 1 82 1.83E-27 T 12-10-2018 IPR035895 HPr-like superfamily VAPA_1c13870 c0286a46176295c7739d32d05a75d76f 775 Gene3D G3DSA:1.10.540.10 2 115 2.0E-13 T 12-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 VAPA_1c13870 c0286a46176295c7739d32d05a75d76f 775 SUPERFAMILY SSF47203 227 367 2.09E-27 T 12-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 VAPA_1c13870 c0286a46176295c7739d32d05a75d76f 775 Gene3D G3DSA:1.10.540.10 397 506 4.5E-23 T 12-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 VAPA_1c13870 c0286a46176295c7739d32d05a75d76f 775 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 511 609 8.2E-20 T 12-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 VAPA_1c13870 c0286a46176295c7739d32d05a75d76f 775 Gene3D G3DSA:2.40.110.10 136 222 6.4E-7 T 12-10-2018 VAPA_1c13870 c0286a46176295c7739d32d05a75d76f 775 Gene3D G3DSA:1.20.140.10 223 375 1.9E-27 T 12-10-2018 VAPA_1c13870 c0286a46176295c7739d32d05a75d76f 775 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 228 360 2.6E-18 T 12-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 VAPA_1c13870 c0286a46176295c7739d32d05a75d76f 775 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 622 771 2.6E-12 T 12-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 VAPA_1c13870 c0286a46176295c7739d32d05a75d76f 775 SUPERFAMILY SSF56645 399 632 7.46E-65 T 12-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 VAPA_1c13870 c0286a46176295c7739d32d05a75d76f 775 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 5 86 4.4E-5 T 12-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 VAPA_1c13870 c0286a46176295c7739d32d05a75d76f 775 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 398 507 9.1E-18 T 12-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 VAPA_1c13870 c0286a46176295c7739d32d05a75d76f 775 Gene3D G3DSA:1.20.140.10 626 775 2.9E-24 T 12-10-2018 VAPA_1c13870 c0286a46176295c7739d32d05a75d76f 775 SUPERFAMILY SSF47203 622 774 2.42E-13 T 12-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 VAPA_1c13870 c0286a46176295c7739d32d05a75d76f 775 Gene3D G3DSA:2.40.110.10 511 625 2.4E-33 T 12-10-2018 VAPA_1c13870 c0286a46176295c7739d32d05a75d76f 775 SUPERFAMILY SSF56645 4 218 2.36E-21 T 12-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 VAPA_1c03950 f046506493ac91f03a150e24087f092b 550 Gene3D G3DSA:2.120.10.30 343 550 2.1E-13 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like VAPA_1c03950 f046506493ac91f03a150e24087f092b 550 Gene3D G3DSA:2.130.10.10 32 253 3.3E-14 T 12-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 VAPA_1c03950 f046506493ac91f03a150e24087f092b 550 SUPERFAMILY SSF101898 45 248 8.63E-27 T 12-10-2018 VAPA_1c03950 f046506493ac91f03a150e24087f092b 550 SUPERFAMILY SSF50998 180 549 7.85E-28 T 12-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily VAPA_1c03950 f046506493ac91f03a150e24087f092b 550 Gene3D G3DSA:2.40.10.500 258 331 1.7E-5 T 12-10-2018 VAPA_2c01160 23175cb1ff6c1dbdac3de16ec5139f42 500 SUPERFAMILY SSF56801 3 499 8.37E-149 T 12-10-2018 VAPA_2c01160 23175cb1ff6c1dbdac3de16ec5139f42 500 Pfam PF00501 AMP-binding enzyme 9 404 1.6E-94 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 VAPA_2c01160 23175cb1ff6c1dbdac3de16ec5139f42 500 Pfam PF13193 AMP-binding enzyme C-terminal domain 413 488 1.4E-23 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain VAPA_2c01160 23175cb1ff6c1dbdac3de16ec5139f42 500 Gene3D G3DSA:3.30.300.310 401 500 1.4E-36 T 12-10-2018 VAPA_2c01160 23175cb1ff6c1dbdac3de16ec5139f42 500 Gene3D G3DSA:3.40.50.12780 2 400 7.8E-109 T 12-10-2018 VAPA_2c01160 23175cb1ff6c1dbdac3de16ec5139f42 500 ProSitePatterns PS00455 Putative AMP-binding domain signature. 152 163 - T 12-10-2018 IPR020845 AMP-binding, conserved site VAPA_1c49940 ad834076e2edc72087a6924c076b39cb 332 Gene3D G3DSA:3.40.190.150 35 322 1.0E-110 T 12-10-2018 VAPA_1c49940 ad834076e2edc72087a6924c076b39cb 332 PIRSF PIRSF017082 5 332 2.4E-87 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c49940 ad834076e2edc72087a6924c076b39cb 332 SUPERFAMILY SSF53850 123 293 1.01E-9 T 12-10-2018 VAPA_1c49940 ad834076e2edc72087a6924c076b39cb 332 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 54 328 4.5E-83 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c49940 ad834076e2edc72087a6924c076b39cb 332 Gene3D G3DSA:3.40.190.10 133 256 1.0E-110 T 12-10-2018 VAPA_1c38580 2734db869e06c740fecbea94810440d5 206 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 8 170 7.9E-14 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 VAPA_1c38580 2734db869e06c740fecbea94810440d5 206 SUPERFAMILY SSF88659 117 174 7.63E-12 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like VAPA_1c38580 2734db869e06c740fecbea94810440d5 206 Pfam PF08281 Sigma-70, region 4 123 170 1.0E-13 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 VAPA_1c38580 2734db869e06c740fecbea94810440d5 206 SUPERFAMILY SSF88946 6 87 7.06E-7 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 VAPA_1c38580 2734db869e06c740fecbea94810440d5 206 Gene3D G3DSA:1.10.10.10 105 186 4.6E-12 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c14210 0b2e910bc5f24a817c7e8b62ec63f55c 529 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 74 452 6.3E-73 T 12-10-2018 IPR000914 Solute-binding protein family 5 domain VAPA_1c14210 0b2e910bc5f24a817c7e8b62ec63f55c 529 Gene3D G3DSA:3.40.190.10 191 511 5.8E-90 T 12-10-2018 VAPA_1c14210 0b2e910bc5f24a817c7e8b62ec63f55c 529 Gene3D G3DSA:3.90.76.10 41 190 5.8E-90 T 12-10-2018 VAPA_1c14210 0b2e910bc5f24a817c7e8b62ec63f55c 529 PIRSF PIRSF002741 3 529 4.3E-57 T 12-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 VAPA_1c14210 0b2e910bc5f24a817c7e8b62ec63f55c 529 SUPERFAMILY SSF53850 32 524 5.25E-101 T 12-10-2018 VAPA_1c14210 0b2e910bc5f24a817c7e8b62ec63f55c 529 Gene3D G3DSA:3.10.105.10 278 504 5.8E-90 T 12-10-2018 VAPA_1c19380 5189a3021ff91776c6bc017d86971cbd 579 SUPERFAMILY SSF52091 454 561 1.35E-11 T 12-10-2018 IPR036513 STAS domain superfamily VAPA_1c19380 5189a3021ff91776c6bc017d86971cbd 579 Gene3D G3DSA:3.30.750.24 448 568 4.4E-16 T 12-10-2018 IPR036513 STAS domain superfamily VAPA_1c19380 5189a3021ff91776c6bc017d86971cbd 579 Pfam PF01740 STAS domain 457 542 6.0E-10 T 12-10-2018 IPR002645 STAS domain VAPA_1c19380 5189a3021ff91776c6bc017d86971cbd 579 Pfam PF00916 Sulfate permease family 35 394 1.0E-70 T 12-10-2018 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 VAPA_1c29860 c008db977b26454b91c9b9de05f90a51 264 Hamap MF_00719 Adenosylcobinamide-GDP ribazoletransferase [cobS]. 1 264 48.39 T 12-10-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7961|MetaCyc: PWY-7963|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970|MetaCyc: PWY-7975 VAPA_1c29860 c008db977b26454b91c9b9de05f90a51 264 Pfam PF02654 Cobalamin-5-phosphate synthase 10 258 8.1E-52 T 12-10-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7961|MetaCyc: PWY-7963|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970|MetaCyc: PWY-7975 VAPA_1c00600 3de58aeeb3b667954c0b3d5e3186ebb1 314 SUPERFAMILY SSF46785 1 83 5.33E-14 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c00600 3de58aeeb3b667954c0b3d5e3186ebb1 314 Gene3D G3DSA:3.40.190.10 167 266 2.9E-90 T 12-10-2018 VAPA_1c00600 3de58aeeb3b667954c0b3d5e3186ebb1 314 Pfam PF03466 LysR substrate binding domain 90 290 6.1E-42 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_1c00600 3de58aeeb3b667954c0b3d5e3186ebb1 314 Gene3D G3DSA:3.40.190.10 93 302 2.9E-90 T 12-10-2018 VAPA_1c00600 3de58aeeb3b667954c0b3d5e3186ebb1 314 Gene3D G3DSA:1.10.10.10 1 83 1.5E-17 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c00600 3de58aeeb3b667954c0b3d5e3186ebb1 314 SUPERFAMILY SSF53850 91 298 3.21E-41 T 12-10-2018 VAPA_1c00600 3de58aeeb3b667954c0b3d5e3186ebb1 314 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 7.9E-10 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c00600 3de58aeeb3b667954c0b3d5e3186ebb1 314 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 7.9E-10 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c00600 3de58aeeb3b667954c0b3d5e3186ebb1 314 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 7.9E-10 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c00600 3de58aeeb3b667954c0b3d5e3186ebb1 314 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 63 3.0E-16 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_2c00500 16273f6e9b1a4ef5a7b5cb44227559b5 186 Pfam PF12802 MarR family 50 108 1.2E-11 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 VAPA_2c00500 16273f6e9b1a4ef5a7b5cb44227559b5 186 SMART SM00347 44 144 1.2E-16 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 VAPA_2c00500 16273f6e9b1a4ef5a7b5cb44227559b5 186 SUPERFAMILY SSF46785 21 159 4.77E-29 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_2c00500 16273f6e9b1a4ef5a7b5cb44227559b5 186 PRINTS PR00598 Bacterial regulatory protein MarR family signature 134 154 4.5E-5 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 VAPA_2c00500 16273f6e9b1a4ef5a7b5cb44227559b5 186 PRINTS PR00598 Bacterial regulatory protein MarR family signature 104 120 4.5E-5 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 VAPA_2c00500 16273f6e9b1a4ef5a7b5cb44227559b5 186 PRINTS PR00598 Bacterial regulatory protein MarR family signature 85 100 4.5E-5 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 VAPA_2c00500 16273f6e9b1a4ef5a7b5cb44227559b5 186 PRINTS PR00598 Bacterial regulatory protein MarR family signature 68 84 4.5E-5 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 VAPA_2c00500 16273f6e9b1a4ef5a7b5cb44227559b5 186 Gene3D G3DSA:1.10.10.10 10 175 9.9E-34 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c21160 c846b662e78c63af655f1271ccfc84ae 118 Gene3D G3DSA:3.30.40.60 2 98 4.1E-8 T 12-10-2018 VAPA_1c06780 6bb7de5bb238599685124fd7e268d762 464 Gene3D G3DSA:1.10.287.130 181 296 5.4E-18 T 12-10-2018 VAPA_1c06780 6bb7de5bb238599685124fd7e268d762 464 PRINTS PR00344 Bacterial sensor protein C-terminal signature 406 416 1.4E-7 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c06780 6bb7de5bb238599685124fd7e268d762 464 PRINTS PR00344 Bacterial sensor protein C-terminal signature 420 438 1.4E-7 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c06780 6bb7de5bb238599685124fd7e268d762 464 PRINTS PR00344 Bacterial sensor protein C-terminal signature 388 402 1.4E-7 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c06780 6bb7de5bb238599685124fd7e268d762 464 SMART SM00388 230 295 1.1E-8 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 VAPA_1c06780 6bb7de5bb238599685124fd7e268d762 464 SUPERFAMILY SSF47384 213 294 6.08E-13 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 VAPA_1c06780 6bb7de5bb238599685124fd7e268d762 464 Gene3D G3DSA:3.30.565.10 302 461 2.6E-26 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_1c06780 6bb7de5bb238599685124fd7e268d762 464 SUPERFAMILY SSF55874 284 459 4.58E-31 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_1c06780 6bb7de5bb238599685124fd7e268d762 464 Pfam PF00512 His Kinase A (phospho-acceptor) domain 232 294 5.8E-9 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 VAPA_1c06780 6bb7de5bb238599685124fd7e268d762 464 SMART SM00387 340 461 2.6E-25 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase VAPA_1c06780 6bb7de5bb238599685124fd7e268d762 464 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 348 458 1.2E-14 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase VAPA_2c00450 010784589688b839a54e01ba84db0faf 272 Gene3D G3DSA:3.90.226.10 3 213 1.8E-61 T 12-10-2018 VAPA_2c00450 010784589688b839a54e01ba84db0faf 272 Gene3D G3DSA:1.10.12.10 215 272 2.1E-13 T 12-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal VAPA_2c00450 010784589688b839a54e01ba84db0faf 272 SUPERFAMILY SSF52096 11 272 2.28E-70 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily VAPA_2c00450 010784589688b839a54e01ba84db0faf 272 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 113 133 - T 12-10-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824 VAPA_2c00450 010784589688b839a54e01ba84db0faf 272 Pfam PF00378 Enoyl-CoA hydratase/isomerase 22 271 4.6E-44 T 12-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 VAPA_2c07470 5f5b8100d001af0fd923a3b2c71de290 590 Pfam PF03865 Haemolysin secretion/activation protein ShlB/FhaC/HecB 228 553 3.7E-106 T 12-10-2018 IPR005565 Haemolysin activator HlyB, C-terminal VAPA_2c07470 5f5b8100d001af0fd923a3b2c71de290 590 Pfam PF17287 POTRA domain 160 219 3.4E-18 T 12-10-2018 IPR035251 ShlB, POTRA domain VAPA_2c07470 5f5b8100d001af0fd923a3b2c71de290 590 PIRSF PIRSF029745 3 574 1.3E-138 T 12-10-2018 IPR027282 Two partner secretion pathway transporter GO:0015031 VAPA_2c07470 5f5b8100d001af0fd923a3b2c71de290 590 Pfam PF08479 POTRA domain, ShlB-type 109 159 2.4E-13 T 12-10-2018 IPR013686 Polypeptide-transport-associated, ShlB-type VAPA_2c07470 5f5b8100d001af0fd923a3b2c71de290 590 Gene3D G3DSA:2.40.160.50 197 573 1.8E-98 T 12-10-2018 VAPA_1c38020 0b8d5cf9f781c7e57b83f5550ec32934 151 Gene3D G3DSA:1.20.1290.10 14 137 2.8E-40 T 12-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 VAPA_1c38020 0b8d5cf9f781c7e57b83f5550ec32934 151 SUPERFAMILY SSF69118 15 135 1.96E-34 T 12-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 VAPA_1c38020 0b8d5cf9f781c7e57b83f5550ec32934 151 Pfam PF02627 Carboxymuconolactone decarboxylase family 43 128 3.6E-21 T 12-10-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 VAPA_1c17520 419d9edbfc9803ec282723ef581ee916 176 Pfam PF00186 Dihydrofolate reductase 9 170 8.1E-57 T 12-10-2018 IPR001796 Dihydrofolate reductase domain GO:0004146|GO:0046654|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 VAPA_1c17520 419d9edbfc9803ec282723ef581ee916 176 Gene3D G3DSA:3.40.430.10 8 175 3.4E-60 T 12-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 VAPA_1c17520 419d9edbfc9803ec282723ef581ee916 176 SUPERFAMILY SSF53597 8 171 3.4E-58 T 12-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 VAPA_1c17520 419d9edbfc9803ec282723ef581ee916 176 PIRSF PIRSF000194 4 173 4.1E-62 T 12-10-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0046654|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614 VAPA_1c17520 419d9edbfc9803ec282723ef581ee916 176 PRINTS PR00070 Dihydrofolate reductase signature 20 30 2.1E-16 T 12-10-2018 VAPA_1c17520 419d9edbfc9803ec282723ef581ee916 176 PRINTS PR00070 Dihydrofolate reductase signature 34 42 2.1E-16 T 12-10-2018 VAPA_1c17520 419d9edbfc9803ec282723ef581ee916 176 PRINTS PR00070 Dihydrofolate reductase signature 47 58 2.1E-16 T 12-10-2018 VAPA_1c17520 419d9edbfc9803ec282723ef581ee916 176 PRINTS PR00070 Dihydrofolate reductase signature 103 117 2.1E-16 T 12-10-2018 VAPA_1c17520 419d9edbfc9803ec282723ef581ee916 176 ProSitePatterns PS00075 Dihydrofolate reductase (DHFR) domain signature. 20 42 - T 12-10-2018 IPR017925 Dihydrofolate reductase conserved site GO:0004146|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-1474151|Reactome: R-HSA-196757|Reactome: R-HSA-539107 VAPA_2c05540 1963b4941d04fe3ca96288900d4ec3c1 1151 Pfam PF08309 LVIVD repeat 242 268 0.6 T 12-10-2018 IPR013211 LVIVD VAPA_2c05540 1963b4941d04fe3ca96288900d4ec3c1 1151 Pfam PF08309 LVIVD repeat 490 514 0.23 T 12-10-2018 IPR013211 LVIVD VAPA_2c05540 1963b4941d04fe3ca96288900d4ec3c1 1151 Pfam PF08309 LVIVD repeat 724 741 1.4 T 12-10-2018 IPR013211 LVIVD VAPA_2c05540 1963b4941d04fe3ca96288900d4ec3c1 1151 Pfam PF08309 LVIVD repeat 852 876 2.3E-4 T 12-10-2018 IPR013211 LVIVD VAPA_1c39580 8f27989064d74c664a4183b1674e81b3 340 SMART SM00062 35 272 1.3E-4 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF VAPA_1c39580 8f27989064d74c664a4183b1674e81b3 340 Pfam PF09084 NMT1/THI5 like 63 246 3.0E-19 T 12-10-2018 IPR015168 SsuA/THI5-like VAPA_1c39580 8f27989064d74c664a4183b1674e81b3 340 Gene3D G3DSA:3.40.190.10 113 214 3.1E-47 T 12-10-2018 VAPA_1c39580 8f27989064d74c664a4183b1674e81b3 340 Gene3D G3DSA:1.10.8.450 246 281 3.1E-47 T 12-10-2018 VAPA_1c39580 8f27989064d74c664a4183b1674e81b3 340 TIGRFAM TIGR01729 taurine_ABC_bnd: taurine ABC transporter, periplasmic binding protein 37 334 2.6E-108 T 12-10-2018 IPR010068 Taurine ABC transporter, substrate-binding protein TauA GO:0015734|GO:0042597 VAPA_1c39580 8f27989064d74c664a4183b1674e81b3 340 SUPERFAMILY SSF53850 34 250 6.47E-40 T 12-10-2018 VAPA_1c39580 8f27989064d74c664a4183b1674e81b3 340 Gene3D G3DSA:3.40.190.10 39 245 3.1E-47 T 12-10-2018 VAPA_1c12450 536743793121ac4866f8b9a2989928aa 350 Pfam PF04166 Pyridoxal phosphate biosynthetic protein PdxA 38 344 2.9E-97 T 12-10-2018 IPR005255 PdxA family GO:0051287|GO:0055114 KEGG: 00750+1.1.1.262 VAPA_1c12450 536743793121ac4866f8b9a2989928aa 350 Gene3D G3DSA:3.40.718.10 2 349 1.6E-119 T 12-10-2018 VAPA_1c12450 536743793121ac4866f8b9a2989928aa 350 SUPERFAMILY SSF53659 7 348 2.88E-95 T 12-10-2018 VAPA_1c12450 536743793121ac4866f8b9a2989928aa 350 TIGRFAM TIGR00557 pdxA: 4-hydroxythreonine-4-phosphate dehydrogenase PdxA 8 348 9.7E-114 T 12-10-2018 IPR005255 PdxA family GO:0051287|GO:0055114 KEGG: 00750+1.1.1.262 VAPA_1c05740 5e3b24cd4c0d0a678ace1286da689d0a 131 Pfam PF04379 ApaG domain 17 101 2.8E-34 T 12-10-2018 IPR007474 ApaG domain VAPA_1c05740 5e3b24cd4c0d0a678ace1286da689d0a 131 SUPERFAMILY SSF110069 4 118 9.81E-47 T 12-10-2018 IPR036767 ApaG domain superfamily VAPA_1c05740 5e3b24cd4c0d0a678ace1286da689d0a 131 Hamap MF_00791 Protein ApaG [apaG]. 1 131 31.686 T 12-10-2018 IPR023065 Uncharacterised protein family ApaG VAPA_1c05740 5e3b24cd4c0d0a678ace1286da689d0a 131 Gene3D G3DSA:2.60.40.1470 1 122 5.0E-47 T 12-10-2018 IPR036767 ApaG domain superfamily VAPA_1c34660 5998c2c56cc38032bd782c0c72e18bb3 320 SUPERFAMILY SSF51412 10 314 3.11E-62 T 12-10-2018 VAPA_1c34660 5998c2c56cc38032bd782c0c72e18bb3 320 Gene3D G3DSA:3.20.20.70 8 320 1.2E-59 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 VAPA_1c34660 5998c2c56cc38032bd782c0c72e18bb3 320 Pfam PF03060 Nitronate monooxygenase 16 308 2.2E-21 T 12-10-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 VAPA_1c18320 df36f50612257af0bb49d55925040937 373 Gene3D G3DSA:3.20.20.210 4 372 1.4E-119 T 12-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 VAPA_1c18320 df36f50612257af0bb49d55925040937 373 Pfam PF01717 Cobalamin-independent synthase, Catalytic domain 14 366 1.6E-17 T 12-10-2018 IPR002629 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 VAPA_1c18320 df36f50612257af0bb49d55925040937 373 SUPERFAMILY SSF51726 12 371 4.32E-73 T 12-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 VAPA_2c11720 ffcb5a1f40f033f48488c77e380ee3b3 301 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 17 72 4.4E-16 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_2c11720 ffcb5a1f40f033f48488c77e380ee3b3 301 Gene3D G3DSA:1.10.10.10 13 104 1.3E-18 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_2c11720 ffcb5a1f40f033f48488c77e380ee3b3 301 SUPERFAMILY SSF53850 108 297 1.99E-18 T 12-10-2018 VAPA_2c11720 ffcb5a1f40f033f48488c77e380ee3b3 301 Gene3D G3DSA:3.40.190.10 168 263 4.4E-23 T 12-10-2018 VAPA_2c11720 ffcb5a1f40f033f48488c77e380ee3b3 301 Gene3D G3DSA:3.40.190.10 111 290 4.4E-23 T 12-10-2018 VAPA_2c11720 ffcb5a1f40f033f48488c77e380ee3b3 301 SUPERFAMILY SSF46785 13 89 1.9E-17 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_2c11720 ffcb5a1f40f033f48488c77e380ee3b3 301 Pfam PF03466 LysR substrate binding domain 101 292 1.3E-10 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_2c11720 ffcb5a1f40f033f48488c77e380ee3b3 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 50 61 2.3E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_2c11720 ffcb5a1f40f033f48488c77e380ee3b3 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 50 2.3E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_2c11720 ffcb5a1f40f033f48488c77e380ee3b3 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 40 2.3E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c25450 3de916b4d8ea1040f8010738844063b3 109 Pfam PF00037 4Fe-4S binding domain 34 56 5.2E-7 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain VAPA_1c25450 3de916b4d8ea1040f8010738844063b3 109 SUPERFAMILY SSF54862 3 76 1.93E-22 T 12-10-2018 VAPA_1c25450 3de916b4d8ea1040f8010738844063b3 109 PRINTS PR00354 7Fe ferredoxin signature 19 29 1.4E-15 T 12-10-2018 IPR000813 7Fe ferredoxin GO:0009055 VAPA_1c25450 3de916b4d8ea1040f8010738844063b3 109 PRINTS PR00354 7Fe ferredoxin signature 35 52 1.4E-15 T 12-10-2018 IPR000813 7Fe ferredoxin GO:0009055 VAPA_1c25450 3de916b4d8ea1040f8010738844063b3 109 PRINTS PR00354 7Fe ferredoxin signature 9 19 1.4E-15 T 12-10-2018 IPR000813 7Fe ferredoxin GO:0009055 VAPA_1c25450 3de916b4d8ea1040f8010738844063b3 109 Pfam PF11953 Domain of unknown function (DUF3470) 68 107 2.7E-16 T 12-10-2018 IPR022569 Ferredoxin, C-terminal VAPA_1c25450 3de916b4d8ea1040f8010738844063b3 109 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 40 51 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site VAPA_1c25450 3de916b4d8ea1040f8010738844063b3 109 Gene3D G3DSA:3.30.70.20 2 104 9.7E-31 T 12-10-2018 VAPA_1c22190 872329cb849769edbcc65e46cc30eb35 205 Gene3D G3DSA:1.10.10.60 1 64 1.3E-14 T 12-10-2018 VAPA_1c22190 872329cb849769edbcc65e46cc30eb35 205 SUPERFAMILY SSF48498 91 204 2.22E-9 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily VAPA_1c22190 872329cb849769edbcc65e46cc30eb35 205 Gene3D G3DSA:1.10.357.10 65 203 3.0E-12 T 12-10-2018 VAPA_1c22190 872329cb849769edbcc65e46cc30eb35 205 Pfam PF00440 Bacterial regulatory proteins, tetR family 23 65 1.4E-12 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 VAPA_1c22190 872329cb849769edbcc65e46cc30eb35 205 SUPERFAMILY SSF46689 12 95 2.15E-16 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 VAPA_1c22190 872329cb849769edbcc65e46cc30eb35 205 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 23 36 1.8E-5 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 VAPA_1c22190 872329cb849769edbcc65e46cc30eb35 205 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 44 67 1.8E-5 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 VAPA_2c00550 9a291fec2d1c1b1030ed8cd88df7eeac 311 PIRSF PIRSF001365 6 311 9.2E-42 T 12-10-2018 IPR002220 DapA-like GO:0016829 VAPA_2c00550 9a291fec2d1c1b1030ed8cd88df7eeac 311 SMART SM01130 10 303 1.8E-44 T 12-10-2018 IPR002220 DapA-like GO:0016829 VAPA_2c00550 9a291fec2d1c1b1030ed8cd88df7eeac 311 SUPERFAMILY SSF51569 10 303 1.57E-58 T 12-10-2018 VAPA_2c00550 9a291fec2d1c1b1030ed8cd88df7eeac 311 Pfam PF00701 Dihydrodipicolinate synthetase family 13 287 1.8E-25 T 12-10-2018 IPR002220 DapA-like GO:0016829 VAPA_2c00550 9a291fec2d1c1b1030ed8cd88df7eeac 311 Gene3D G3DSA:3.20.20.70 4 311 2.7E-97 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 VAPA_1c02110 6138c7717218e715ebc898fd5e7ec7b0 399 Gene3D G3DSA:2.30.40.10 14 389 4.9E-148 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 VAPA_1c02110 6138c7717218e715ebc898fd5e7ec7b0 399 Pfam PF01979 Amidohydrolase family 68 375 6.3E-11 T 12-10-2018 IPR006680 Amidohydrolase-related GO:0016787 VAPA_1c02110 6138c7717218e715ebc898fd5e7ec7b0 399 SUPERFAMILY SSF51338 13 387 1.3E-15 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 VAPA_1c02110 6138c7717218e715ebc898fd5e7ec7b0 399 SUPERFAMILY SSF51556 68 329 7.78E-17 T 12-10-2018 IPR032466 Metal-dependent hydrolase VAPA_1c02110 6138c7717218e715ebc898fd5e7ec7b0 399 Gene3D G3DSA:3.20.20.140 71 328 4.9E-148 T 12-10-2018 VAPA_1c34250 bf52a111de9cf6ac9f031ebcacd285a0 142 Pfam PF02627 Carboxymuconolactone decarboxylase family 42 128 6.1E-13 T 12-10-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 VAPA_1c34250 bf52a111de9cf6ac9f031ebcacd285a0 142 Gene3D G3DSA:1.20.1290.10 10 135 7.2E-28 T 12-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 VAPA_1c34250 bf52a111de9cf6ac9f031ebcacd285a0 142 SUPERFAMILY SSF69118 11 136 2.55E-25 T 12-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 VAPA_1c09220 b631fcc075cca87cc1ae8108b5e9bb0e 291 Hamap MF_00188 Protease HtpX [htpX]. 1 289 24.478 T 12-10-2018 IPR022919 Peptidase M48, protease HtpX, putative GO:0004222 VAPA_1c09220 b631fcc075cca87cc1ae8108b5e9bb0e 291 Gene3D G3DSA:3.30.2010.10 71 162 1.5E-30 T 12-10-2018 VAPA_1c09220 b631fcc075cca87cc1ae8108b5e9bb0e 291 Pfam PF01435 Peptidase family M48 81 288 5.7E-38 T 12-10-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 VAPA_1c30020 926c288fce73dd7c96002c4c2692a38d 289 Gene3D G3DSA:3.40.50.1980 41 152 6.1E-30 T 12-10-2018 VAPA_1c30020 926c288fce73dd7c96002c4c2692a38d 289 Pfam PF01497 Periplasmic binding protein 44 259 1.2E-26 T 12-10-2018 IPR002491 ABC transporter periplasmic binding domain VAPA_1c30020 926c288fce73dd7c96002c4c2692a38d 289 Gene3D G3DSA:3.40.50.1980 157 287 9.8E-27 T 12-10-2018 VAPA_1c30020 926c288fce73dd7c96002c4c2692a38d 289 SUPERFAMILY SSF53807 20 284 1.14E-49 T 12-10-2018 VAPA_2c09880 53075d3a5733fc3fbf31b9cf7dd42467 293 Gene3D G3DSA:3.40.190.10 162 255 1.2E-36 T 12-10-2018 VAPA_2c09880 53075d3a5733fc3fbf31b9cf7dd42467 293 Gene3D G3DSA:3.40.190.10 90 281 1.2E-36 T 12-10-2018 VAPA_2c09880 53075d3a5733fc3fbf31b9cf7dd42467 293 SUPERFAMILY SSF53850 89 286 4.89E-32 T 12-10-2018 VAPA_2c09880 53075d3a5733fc3fbf31b9cf7dd42467 293 SUPERFAMILY SSF46785 1 104 2.1E-17 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_2c09880 53075d3a5733fc3fbf31b9cf7dd42467 293 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 1.1E-14 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_2c09880 53075d3a5733fc3fbf31b9cf7dd42467 293 Gene3D G3DSA:1.10.10.10 1 86 7.6E-19 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_2c09880 53075d3a5733fc3fbf31b9cf7dd42467 293 Pfam PF03466 LysR substrate binding domain 89 282 1.1E-31 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_1c31010 231095957303e9b343c3a289bcaacf73 331 PIRSF PIRSF017082 8 329 8.7E-72 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c31010 231095957303e9b343c3a289bcaacf73 331 Gene3D G3DSA:3.40.190.150 37 313 5.6E-80 T 12-10-2018 VAPA_1c31010 231095957303e9b343c3a289bcaacf73 331 SUPERFAMILY SSF53850 123 294 1.0E-9 T 12-10-2018 VAPA_1c31010 231095957303e9b343c3a289bcaacf73 331 Gene3D G3DSA:3.40.190.10 133 254 5.6E-80 T 12-10-2018 VAPA_1c31010 231095957303e9b343c3a289bcaacf73 331 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 58 326 1.6E-65 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_2c06800 541a1878294bccfe9d2e72b7f28f496e 273 SUPERFAMILY SSF46785 30 97 2.0E-13 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_2c06800 541a1878294bccfe9d2e72b7f28f496e 273 Pfam PF01614 Bacterial transcriptional regulator 150 272 1.4E-10 T 12-10-2018 IPR014757 Transcription regulator IclR, C-terminal VAPA_2c06800 541a1878294bccfe9d2e72b7f28f496e 273 Pfam PF09339 IclR helix-turn-helix domain 33 82 1.6E-14 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 VAPA_2c06800 541a1878294bccfe9d2e72b7f28f496e 273 Gene3D G3DSA:3.30.450.40 102 273 2.2E-35 T 12-10-2018 IPR029016 GAF-like domain superfamily VAPA_2c06800 541a1878294bccfe9d2e72b7f28f496e 273 SUPERFAMILY SSF55781 103 272 2.29E-33 T 12-10-2018 VAPA_2c06800 541a1878294bccfe9d2e72b7f28f496e 273 SMART SM00346 30 120 4.7E-18 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 VAPA_2c06800 541a1878294bccfe9d2e72b7f28f496e 273 Gene3D G3DSA:1.10.10.10 19 97 5.7E-17 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c08930 e27eeafa5260058707e05c8023860768 345 SUPERFAMILY SSF53850 74 271 1.19E-10 T 12-10-2018 VAPA_1c08930 e27eeafa5260058707e05c8023860768 345 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 39 325 2.7E-75 T 12-10-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0030288|GO:0055085 VAPA_1c08930 e27eeafa5260058707e05c8023860768 345 Gene3D G3DSA:3.40.190.170 30 343 1.7E-128 T 12-10-2018 IPR038404 TRAP transporter solute receptor DctP superfamily VAPA_1c08930 e27eeafa5260058707e05c8023860768 345 PIRSF PIRSF006470 2 342 7.1E-85 T 12-10-2018 IPR004682 TRAP transporter solute receptor, DctP family GO:0030288|GO:0055085 VAPA_1c08930 e27eeafa5260058707e05c8023860768 345 TIGRFAM TIGR00787 dctP: TRAP transporter solute receptor, DctP family 41 281 5.7E-59 T 12-10-2018 IPR004682 TRAP transporter solute receptor, DctP family GO:0030288|GO:0055085 VAPA_1c27180 02fee9d1b73fdeadc5d082407cf3073f 171 SUPERFAMILY SSF54523 11 100 3.69E-16 T 12-10-2018 VAPA_1c27180 02fee9d1b73fdeadc5d082407cf3073f 171 Gene3D G3DSA:3.30.700.10 11 168 5.8E-13 T 12-10-2018 VAPA_1c27180 02fee9d1b73fdeadc5d082407cf3073f 171 Pfam PF12019 Type II transport protein GspH 47 157 3.5E-19 T 12-10-2018 IPR022346 General secretion pathway, GspH GO:0008565|GO:0015627|GO:0015628 VAPA_1c27180 02fee9d1b73fdeadc5d082407cf3073f 171 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 9 29 - T 12-10-2018 IPR012902 Prokaryotic N-terminal methylation site VAPA_1c27180 02fee9d1b73fdeadc5d082407cf3073f 171 Pfam PF07963 Prokaryotic N-terminal methylation motif 7 30 2.2E-6 T 12-10-2018 IPR012902 Prokaryotic N-terminal methylation site VAPA_1c27180 02fee9d1b73fdeadc5d082407cf3073f 171 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 9 30 3.0E-5 T 12-10-2018 IPR012902 Prokaryotic N-terminal methylation site VAPA_1c25510 596f710fe49a913ac63249702c04c43e 272 Gene3D G3DSA:3.30.1360.130 118 260 9.6E-83 T 12-10-2018 VAPA_1c25510 596f710fe49a913ac63249702c04c43e 272 SUPERFAMILY SSF63992 1 271 1.15E-98 T 12-10-2018 IPR036177 Peptidase M55, D-aminopeptidase superfamily VAPA_1c25510 596f710fe49a913ac63249702c04c43e 272 PIRSF PIRSF015853 1 272 2.9E-99 T 12-10-2018 IPR007035 Peptidase M55, D-aminopeptidase VAPA_1c25510 596f710fe49a913ac63249702c04c43e 272 Gene3D G3DSA:3.40.50.10780 1 214 9.6E-83 T 12-10-2018 IPR027476 D-aminopeptidase, N-terminal VAPA_1c25510 596f710fe49a913ac63249702c04c43e 272 Pfam PF04951 D-aminopeptidase 1 262 1.2E-94 T 12-10-2018 IPR007035 Peptidase M55, D-aminopeptidase VAPA_2c10470 aa3d65d7f8e82d3d4887634f5c67ba4e 502 SUPERFAMILY SSF53720 14 491 1.57E-177 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 VAPA_2c10470 aa3d65d7f8e82d3d4887634f5c67ba4e 502 Gene3D G3DSA:3.40.605.10 34 485 8.6E-192 T 12-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 VAPA_2c10470 aa3d65d7f8e82d3d4887634f5c67ba4e 502 Gene3D G3DSA:3.40.309.10 265 457 8.6E-192 T 12-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 VAPA_2c10470 aa3d65d7f8e82d3d4887634f5c67ba4e 502 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 289 300 - T 12-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 VAPA_2c10470 aa3d65d7f8e82d3d4887634f5c67ba4e 502 Pfam PF00171 Aldehyde dehydrogenase family 26 488 1.4E-182 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 VAPA_2c03580 f7f72c91285bb4ee07c2698b6d2bf33e 226 Pfam PF14518 Iron-containing redox enzyme 39 206 5.2E-24 T 12-10-2018 VAPA_2c03580 f7f72c91285bb4ee07c2698b6d2bf33e 226 Gene3D G3DSA:1.20.910.10 4 216 2.4E-53 T 12-10-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 VAPA_2c03580 f7f72c91285bb4ee07c2698b6d2bf33e 226 SUPERFAMILY SSF48613 1 214 5.7E-51 T 12-10-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 VAPA_1c48010 23d44edc24f1974a2db33f60d98d9640 354 Hamap MF_00016 Holliday junction ATP-dependent DNA helicase RuvB [ruvB]. 1 354 182.529 T 12-10-2018 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 VAPA_1c48010 23d44edc24f1974a2db33f60d98d9640 354 SUPERFAMILY SSF46785 269 342 2.04E-25 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c48010 23d44edc24f1974a2db33f60d98d9640 354 SMART SM00382 63 190 4.6E-10 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c48010 23d44edc24f1974a2db33f60d98d9640 354 SUPERFAMILY SSF52540 32 263 3.61E-54 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c48010 23d44edc24f1974a2db33f60d98d9640 354 Gene3D G3DSA:1.10.8.60 194 267 4.0E-31 T 12-10-2018 VAPA_1c48010 23d44edc24f1974a2db33f60d98d9640 354 Pfam PF05491 Holliday junction DNA helicase ruvB C-terminus 265 338 4.6E-33 T 12-10-2018 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 VAPA_1c48010 23d44edc24f1974a2db33f60d98d9640 354 Gene3D G3DSA:3.40.50.300 32 193 1.5E-38 T 12-10-2018 VAPA_1c48010 23d44edc24f1974a2db33f60d98d9640 354 Gene3D G3DSA:1.10.10.10 269 346 7.4E-33 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c48010 23d44edc24f1974a2db33f60d98d9640 354 ProDom PD005323 DNA HELICASE HOLLIDAY JUNCTION RUVB NUCLEOTIDE-BINDING ATP-BINDING SOS RECOMBINATION RESPONSE 262 340 2.0E-38 T 12-10-2018 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 VAPA_1c48010 23d44edc24f1974a2db33f60d98d9640 354 TIGRFAM TIGR00635 ruvB: Holliday junction DNA helicase RuvB 36 338 4.1E-148 T 12-10-2018 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 VAPA_1c48010 23d44edc24f1974a2db33f60d98d9640 354 Pfam PF05496 Holliday junction DNA helicase ruvB N-terminus 21 247 1.8E-116 T 12-10-2018 IPR008824 Holliday junction DNA helicase ruvB, N-terminal GO:0006281|GO:0006310|GO:0009378 VAPA_1c50660 c4bb7ccea9c8e8d545d5c06764f9e400 301 Pfam PF03466 LysR substrate binding domain 89 265 1.7E-22 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_1c50660 c4bb7ccea9c8e8d545d5c06764f9e400 301 Gene3D G3DSA:3.40.190.10 161 254 2.3E-48 T 12-10-2018 VAPA_1c50660 c4bb7ccea9c8e8d545d5c06764f9e400 301 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 64 1.4E-22 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c50660 c4bb7ccea9c8e8d545d5c06764f9e400 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 7.0E-11 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c50660 c4bb7ccea9c8e8d545d5c06764f9e400 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 7.0E-11 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c50660 c4bb7ccea9c8e8d545d5c06764f9e400 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 7.0E-11 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c50660 c4bb7ccea9c8e8d545d5c06764f9e400 301 SUPERFAMILY SSF53850 88 279 7.78E-23 T 12-10-2018 VAPA_1c50660 c4bb7ccea9c8e8d545d5c06764f9e400 301 SUPERFAMILY SSF46785 2 111 2.51E-26 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c50660 c4bb7ccea9c8e8d545d5c06764f9e400 301 Gene3D G3DSA:1.10.10.10 2 85 4.0E-28 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c50660 c4bb7ccea9c8e8d545d5c06764f9e400 301 Gene3D G3DSA:3.40.190.10 95 261 2.3E-48 T 12-10-2018 VAPA_2c11430 f46b677e4d29ec0039a39f76d25ea16c 525 PIRSF PIRSF000137 1 525 8.0E-146 T 12-10-2018 IPR012132 Glucose-methanol-choline oxidoreductase GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 VAPA_2c11430 f46b677e4d29ec0039a39f76d25ea16c 525 SUPERFAMILY SSF51905 1 524 1.25E-82 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_2c11430 f46b677e4d29ec0039a39f76d25ea16c 525 Pfam PF05199 GMC oxidoreductase 381 519 5.8E-41 T 12-10-2018 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 VAPA_2c11430 f46b677e4d29ec0039a39f76d25ea16c 525 Gene3D G3DSA:1.10.1220.110 92 146 1.7E-178 T 12-10-2018 VAPA_2c11430 f46b677e4d29ec0039a39f76d25ea16c 525 Gene3D G3DSA:3.50.50.60 2 523 1.7E-178 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_2c11430 f46b677e4d29ec0039a39f76d25ea16c 525 ProSitePatterns PS00623 GMC oxidoreductases signature 1. 77 100 - T 12-10-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 VAPA_2c11430 f46b677e4d29ec0039a39f76d25ea16c 525 ProSitePatterns PS00624 GMC oxidoreductases signature 2. 250 264 - T 12-10-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 VAPA_2c11430 f46b677e4d29ec0039a39f76d25ea16c 525 Gene3D G3DSA:3.30.410.40 147 466 1.7E-178 T 12-10-2018 VAPA_2c11430 f46b677e4d29ec0039a39f76d25ea16c 525 Pfam PF00732 GMC oxidoreductase 2 291 4.0E-75 T 12-10-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 VAPA_2c11430 f46b677e4d29ec0039a39f76d25ea16c 525 SUPERFAMILY SSF54373 286 469 9.52E-43 T 12-10-2018 VAPA_2c11430 f46b677e4d29ec0039a39f76d25ea16c 525 Gene3D G3DSA:4.10.450.10 35 192 1.7E-178 T 12-10-2018 IPR027424 Glucose Oxidase, domain 2 KEGG: 00260+1.2.1.8+1.1.99.1|MetaCyc: PWY-3722|MetaCyc: PWY-7494|Reactome: R-HSA-6798163 VAPA_1c18800 deb6762949583323ff6b13d90a1c8126 210 Gene3D G3DSA:3.90.280.10 25 191 4.4E-38 T 12-10-2018 IPR036610 PEBP-like superfamily VAPA_1c18800 deb6762949583323ff6b13d90a1c8126 210 Pfam PF01161 Phosphatidylethanolamine-binding protein 50 188 1.7E-24 T 12-10-2018 IPR008914 Phosphatidylethanolamine-binding protein VAPA_1c18800 deb6762949583323ff6b13d90a1c8126 210 TIGRFAM TIGR00481 TIGR00481: Raf kinase inhibitor-like protein, YbhB/YbcL family 54 184 4.4E-18 T 12-10-2018 IPR005247 YbhB/YbcL VAPA_1c18800 deb6762949583323ff6b13d90a1c8126 210 SUPERFAMILY SSF49777 39 190 3.27E-31 T 12-10-2018 IPR036610 PEBP-like superfamily VAPA_2c06630 29ba2af908bd55b37772bd1ffe7351e3 426 Pfam PF13378 Enolase C-terminal domain-like 201 417 3.8E-57 T 12-10-2018 IPR029065 Enolase C-terminal domain-like VAPA_2c06630 29ba2af908bd55b37772bd1ffe7351e3 426 Gene3D G3DSA:3.20.20.120 131 426 1.0E-111 T 12-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily VAPA_2c06630 29ba2af908bd55b37772bd1ffe7351e3 426 ProSitePatterns PS00909 Mandelate racemase / muconate lactonizing enzyme family signature 2. 244 275 - T 12-10-2018 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 VAPA_2c06630 29ba2af908bd55b37772bd1ffe7351e3 426 SUPERFAMILY SSF51604 183 425 9.69E-68 T 12-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily VAPA_2c06630 29ba2af908bd55b37772bd1ffe7351e3 426 SUPERFAMILY SSF54826 4 138 1.48E-38 T 12-10-2018 VAPA_2c06630 29ba2af908bd55b37772bd1ffe7351e3 426 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 34 135 9.9E-8 T 12-10-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain VAPA_2c06630 29ba2af908bd55b37772bd1ffe7351e3 426 SMART SM00922 198 294 1.1E-25 T 12-10-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal VAPA_2c06630 29ba2af908bd55b37772bd1ffe7351e3 426 Gene3D G3DSA:3.30.390.10 1 130 4.2E-57 T 12-10-2018 IPR029017 Enolase-like, N-terminal VAPA_2c02990 c6cd5bb2e3edb348e6910a4f976f1c14 458 Pfam PF10397 Adenylosuccinate lyase C-terminus 372 449 1.2E-20 T 12-10-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 VAPA_2c02990 c6cd5bb2e3edb348e6910a4f976f1c14 458 Pfam PF00206 Lyase 25 306 2.3E-54 T 12-10-2018 IPR022761 Fumarate lyase, N-terminal VAPA_2c02990 c6cd5bb2e3edb348e6910a4f976f1c14 458 Gene3D G3DSA:1.20.200.10 113 368 2.8E-98 T 12-10-2018 VAPA_2c02990 c6cd5bb2e3edb348e6910a4f976f1c14 458 PRINTS PR00145 Argininosuccinate lyase family signature 238 262 8.6E-13 T 12-10-2018 VAPA_2c02990 c6cd5bb2e3edb348e6910a4f976f1c14 458 PRINTS PR00145 Argininosuccinate lyase family signature 107 129 8.6E-13 T 12-10-2018 VAPA_2c02990 c6cd5bb2e3edb348e6910a4f976f1c14 458 PRINTS PR00145 Argininosuccinate lyase family signature 283 299 8.6E-13 T 12-10-2018 VAPA_2c02990 c6cd5bb2e3edb348e6910a4f976f1c14 458 PRINTS PR00145 Argininosuccinate lyase family signature 148 168 8.6E-13 T 12-10-2018 VAPA_2c02990 c6cd5bb2e3edb348e6910a4f976f1c14 458 SUPERFAMILY SSF48557 19 451 9.42E-125 T 12-10-2018 IPR008948 L-Aspartase-like GO:0003824 VAPA_2c02990 c6cd5bb2e3edb348e6910a4f976f1c14 458 TIGRFAM TIGR02426 protocat_pcaB: 3-carboxy-cis,cis-muconate cycloisomerase 17 355 3.1E-107 T 12-10-2018 IPR012789 3-carboxy-cis,cis-muconate cycloisomerase GO:0019619|GO:0047472 KEGG: 00362+5.5.1.2 VAPA_2c02990 c6cd5bb2e3edb348e6910a4f976f1c14 458 Gene3D G3DSA:1.10.275.10 11 112 4.4E-36 T 12-10-2018 IPR024083 Fumarase/histidase, N-terminal VAPA_2c02990 c6cd5bb2e3edb348e6910a4f976f1c14 458 PRINTS PR00149 Fumarate lyase superfamily signature 238 265 1.2E-25 T 12-10-2018 IPR000362 Fumarate lyase family VAPA_2c02990 c6cd5bb2e3edb348e6910a4f976f1c14 458 PRINTS PR00149 Fumarate lyase superfamily signature 108 126 1.2E-25 T 12-10-2018 IPR000362 Fumarate lyase family VAPA_2c02990 c6cd5bb2e3edb348e6910a4f976f1c14 458 PRINTS PR00149 Fumarate lyase superfamily signature 153 171 1.2E-25 T 12-10-2018 IPR000362 Fumarate lyase family VAPA_2c02990 c6cd5bb2e3edb348e6910a4f976f1c14 458 PRINTS PR00149 Fumarate lyase superfamily signature 283 299 1.2E-25 T 12-10-2018 IPR000362 Fumarate lyase family VAPA_2c02990 c6cd5bb2e3edb348e6910a4f976f1c14 458 SMART SM00998 371 450 1.3E-30 T 12-10-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 VAPA_2c02990 c6cd5bb2e3edb348e6910a4f976f1c14 458 Gene3D G3DSA:1.10.40.30 370 455 1.5E-32 T 12-10-2018 VAPA_1c41700 c7ffa1b5992234656d8bab7f063bc9f5 211 TIGRFAM TIGR00057 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family 7 204 4.8E-59 T 12-10-2018 IPR006070 YrdC-like domain GO:0003725 VAPA_1c41700 c7ffa1b5992234656d8bab7f063bc9f5 211 Pfam PF01300 Telomere recombination 23 202 2.3E-44 T 12-10-2018 IPR006070 YrdC-like domain GO:0003725 VAPA_1c41700 c7ffa1b5992234656d8bab7f063bc9f5 211 SUPERFAMILY SSF55821 1 206 6.1E-61 T 12-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily VAPA_1c41700 c7ffa1b5992234656d8bab7f063bc9f5 211 Gene3D G3DSA:3.90.870.10 1 208 5.1E-62 T 12-10-2018 VAPA_1c06860 c516cf5a7dec9e5d27b209e5dedb828f 212 Pfam PF13417 Glutathione S-transferase, N-terminal domain 3 78 8.4E-15 T 12-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 VAPA_1c06860 c516cf5a7dec9e5d27b209e5dedb828f 212 SUPERFAMILY SSF52833 1 83 4.99E-24 T 12-10-2018 IPR036249 Thioredoxin-like superfamily VAPA_1c06860 c516cf5a7dec9e5d27b209e5dedb828f 212 Gene3D G3DSA:3.40.30.10 1 85 1.9E-26 T 12-10-2018 VAPA_1c06860 c516cf5a7dec9e5d27b209e5dedb828f 212 SUPERFAMILY SSF47616 80 210 5.97E-26 T 12-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily VAPA_1c06860 c516cf5a7dec9e5d27b209e5dedb828f 212 TIGRFAM TIGR01262 maiA: maleylacetoacetate isomerase 2 211 4.5E-82 T 12-10-2018 IPR005955 Glutathione S-transferases, class Zeta GO:0003824|GO:0005737|GO:0009072 Reactome: R-HSA-156590|Reactome: R-HSA-204174|Reactome: R-HSA-71182 VAPA_1c06860 c516cf5a7dec9e5d27b209e5dedb828f 212 Gene3D G3DSA:1.20.1050.10 86 212 1.0E-45 T 12-10-2018 VAPA_1c02480 468949f86c8710fee5ae7c1d8b4141bd 1211 Pfam PF14331 ImcF-related N-terminal domain 210 469 8.5E-92 T 12-10-2018 IPR025743 ImcF-related, N-terminal domain VAPA_1c02480 468949f86c8710fee5ae7c1d8b4141bd 1211 TIGRFAM TIGR03348 VI_IcmF: type VI secretion protein IcmF 15 1209 0.0 T 12-10-2018 IPR017731 Type VI secretion system, IcmF VAPA_1c02480 468949f86c8710fee5ae7c1d8b4141bd 1211 Pfam PF06744 Type VI secretion protein IcmF C-terminal 956 1159 4.5E-62 T 12-10-2018 IPR010623 Type VI secretion system IcmF, C-terminal VAPA_1c02480 468949f86c8710fee5ae7c1d8b4141bd 1211 SUPERFAMILY SSF52540 140 293 3.58E-9 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c02480 468949f86c8710fee5ae7c1d8b4141bd 1211 Pfam PF06761 Intracellular multiplication and human macrophage-killing 526 834 5.6E-85 T 12-10-2018 IPR009612 ImcF-related VAPA_1c52970 1d927c8a758b63d1be4cb7348866401c 67 Pfam PF10932 Protein of unknown function (DUF2783) 1 58 1.3E-24 T 12-10-2018 IPR021233 Protein of unknown function DUF2783 VAPA_1c21800 985f8039d71435f8e23ca18601d3be8c 335 Pfam PF00561 alpha/beta hydrolase fold 83 315 1.6E-26 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 VAPA_1c21800 985f8039d71435f8e23ca18601d3be8c 335 SUPERFAMILY SSF53474 63 334 4.59E-65 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c21800 985f8039d71435f8e23ca18601d3be8c 335 PRINTS PR00111 Alpha/beta hydrolase fold signature 152 165 3.4E-10 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 VAPA_1c21800 985f8039d71435f8e23ca18601d3be8c 335 PRINTS PR00111 Alpha/beta hydrolase fold signature 278 292 3.4E-10 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 VAPA_1c21800 985f8039d71435f8e23ca18601d3be8c 335 PRINTS PR00111 Alpha/beta hydrolase fold signature 108 123 3.4E-10 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 VAPA_1c21800 985f8039d71435f8e23ca18601d3be8c 335 PRINTS PR00412 Epoxide hydrolase signature 108 123 6.8E-6 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 VAPA_1c21800 985f8039d71435f8e23ca18601d3be8c 335 PRINTS PR00412 Epoxide hydrolase signature 276 292 6.8E-6 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 VAPA_1c21800 985f8039d71435f8e23ca18601d3be8c 335 PRINTS PR00412 Epoxide hydrolase signature 88 106 6.8E-6 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 VAPA_1c21800 985f8039d71435f8e23ca18601d3be8c 335 Gene3D G3DSA:3.40.50.1820 63 334 7.9E-87 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c41940 3ddbde528969089b9a9600ca9ab2c5a7 668 PRINTS PR01165 Cytochrome c oxidase subunit I signature 393 411 5.4E-94 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 VAPA_1c41940 3ddbde528969089b9a9600ca9ab2c5a7 668 PRINTS PR01165 Cytochrome c oxidase subunit I signature 176 188 5.4E-94 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 VAPA_1c41940 3ddbde528969089b9a9600ca9ab2c5a7 668 PRINTS PR01165 Cytochrome c oxidase subunit I signature 358 379 5.4E-94 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 VAPA_1c41940 3ddbde528969089b9a9600ca9ab2c5a7 668 PRINTS PR01165 Cytochrome c oxidase subunit I signature 237 256 5.4E-94 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 VAPA_1c41940 3ddbde528969089b9a9600ca9ab2c5a7 668 PRINTS PR01165 Cytochrome c oxidase subunit I signature 288 309 5.4E-94 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 VAPA_1c41940 3ddbde528969089b9a9600ca9ab2c5a7 668 PRINTS PR01165 Cytochrome c oxidase subunit I signature 334 349 5.4E-94 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 VAPA_1c41940 3ddbde528969089b9a9600ca9ab2c5a7 668 PRINTS PR01165 Cytochrome c oxidase subunit I signature 57 82 5.4E-94 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 VAPA_1c41940 3ddbde528969089b9a9600ca9ab2c5a7 668 PRINTS PR01165 Cytochrome c oxidase subunit I signature 471 492 5.4E-94 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 VAPA_1c41940 3ddbde528969089b9a9600ca9ab2c5a7 668 PRINTS PR01165 Cytochrome c oxidase subunit I signature 208 226 5.4E-94 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 VAPA_1c41940 3ddbde528969089b9a9600ca9ab2c5a7 668 PRINTS PR01165 Cytochrome c oxidase subunit I signature 107 130 5.4E-94 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 VAPA_1c41940 3ddbde528969089b9a9600ca9ab2c5a7 668 PRINTS PR01165 Cytochrome c oxidase subunit I signature 134 158 5.4E-94 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 VAPA_1c41940 3ddbde528969089b9a9600ca9ab2c5a7 668 PRINTS PR01165 Cytochrome c oxidase subunit I signature 421 440 5.4E-94 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 VAPA_1c41940 3ddbde528969089b9a9600ca9ab2c5a7 668 TIGRFAM TIGR02843 CyoB: cytochrome o ubiquinol oxidase, subunit I 12 656 0.0 T 12-10-2018 IPR014207 Cytochrome o ubiquinol oxidase, subunit I GO:0016682|GO:0055114 MetaCyc: PWY-7544 VAPA_1c41940 3ddbde528969089b9a9600ca9ab2c5a7 668 Gene3D G3DSA:1.20.210.10 40 573 1.3E-187 T 12-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 VAPA_1c41940 3ddbde528969089b9a9600ca9ab2c5a7 668 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 290 344 - T 12-10-2018 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 VAPA_1c41940 3ddbde528969089b9a9600ca9ab2c5a7 668 SUPERFAMILY SSF81442 53 570 2.62E-177 T 12-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 VAPA_1c41940 3ddbde528969089b9a9600ca9ab2c5a7 668 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 66 514 5.1E-135 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 VAPA_2c08540 9c8f6d9664aac7dd304a8ff5ed3f4888 284 SMART SM00062 44 277 0.0076 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF VAPA_2c08540 9c8f6d9664aac7dd304a8ff5ed3f4888 284 Gene3D G3DSA:3.40.190.10 30 96 4.5E-8 T 12-10-2018 VAPA_2c08540 9c8f6d9664aac7dd304a8ff5ed3f4888 284 Gene3D G3DSA:3.40.190.10 131 271 9.4E-12 T 12-10-2018 VAPA_2c08540 9c8f6d9664aac7dd304a8ff5ed3f4888 284 Gene3D G3DSA:3.40.190.10 140 239 9.4E-12 T 12-10-2018 VAPA_2c08540 9c8f6d9664aac7dd304a8ff5ed3f4888 284 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 132 273 1.1E-8 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF VAPA_2c08540 9c8f6d9664aac7dd304a8ff5ed3f4888 284 SUPERFAMILY SSF53850 35 276 2.69E-20 T 12-10-2018 VAPA_1c18280 843879918ca6f5515c91f407ce148a3f 339 Gene3D G3DSA:1.10.287.470 180 209 6.0E-25 T 12-10-2018 VAPA_1c18280 843879918ca6f5515c91f407ce148a3f 339 SUPERFAMILY SSF111369 146 329 1.24E-10 T 12-10-2018 VAPA_1c18280 843879918ca6f5515c91f407ce148a3f 339 Pfam PF13533 Biotin-lipoyl like 45 91 2.3E-8 T 12-10-2018 IPR039562 Membrane fusion protein, biotin-lipoyl like domain VAPA_1c18280 843879918ca6f5515c91f407ce148a3f 339 Gene3D G3DSA:1.10.287.470 108 174 1.5E-6 T 12-10-2018 VAPA_1c18280 843879918ca6f5515c91f407ce148a3f 339 SUPERFAMILY SSF111369 42 132 5.23E-5 T 12-10-2018 VAPA_1c18280 843879918ca6f5515c91f407ce148a3f 339 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 55 75 1.5E-5 T 12-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 VAPA_1c18280 843879918ca6f5515c91f407ce148a3f 339 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 313 337 1.5E-5 T 12-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 VAPA_1c18280 843879918ca6f5515c91f407ce148a3f 339 Pfam PF13437 HlyD family secretion protein 210 321 7.7E-15 T 12-10-2018 VAPA_1c18280 843879918ca6f5515c91f407ce148a3f 339 Gene3D G3DSA:2.40.50.100 43 101 7.4E-9 T 12-10-2018 VAPA_1c18280 843879918ca6f5515c91f407ce148a3f 339 Gene3D G3DSA:2.40.30.170 245 331 6.0E-25 T 12-10-2018 VAPA_1c18280 843879918ca6f5515c91f407ce148a3f 339 Gene3D G3DSA:2.40.50.100 210 244 6.0E-25 T 12-10-2018 VAPA_2c05700 0f9eaa10e45683560f4a946a757851c9 421 Gene3D G3DSA:3.40.50.720 2 244 5.6E-56 T 12-10-2018 VAPA_2c05700 0f9eaa10e45683560f4a946a757851c9 421 SUPERFAMILY SSF51735 3 239 2.11E-56 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_2c05700 0f9eaa10e45683560f4a946a757851c9 421 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 8 237 1.7E-38 T 12-10-2018 VAPA_2c05700 0f9eaa10e45683560f4a946a757851c9 421 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 126 134 1.1E-5 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c05700 0f9eaa10e45683560f4a946a757851c9 421 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 146 165 1.1E-5 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c05700 0f9eaa10e45683560f4a946a757851c9 421 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 73 84 1.1E-5 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c05700 0f9eaa10e45683560f4a946a757851c9 421 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 146 165 3.5E-30 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c05700 0f9eaa10e45683560f4a946a757851c9 421 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 201 221 3.5E-30 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c05700 0f9eaa10e45683560f4a946a757851c9 421 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 73 84 3.5E-30 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c05700 0f9eaa10e45683560f4a946a757851c9 421 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 120 136 3.5E-30 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c05700 0f9eaa10e45683560f4a946a757851c9 421 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 3.5E-30 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c05700 0f9eaa10e45683560f4a946a757851c9 421 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 165 182 3.5E-30 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c45460 1873e5078d9d55c7ba98241fffbff2cc 488 SUPERFAMILY SSF63411 279 468 2.83E-32 T 12-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 VAPA_1c45460 1873e5078d9d55c7ba98241fffbff2cc 488 SUPERFAMILY SSF63411 52 266 1.45E-60 T 12-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 VAPA_1c45460 1873e5078d9d55c7ba98241fffbff2cc 488 Gene3D G3DSA:3.30.830.10 272 468 5.0E-49 T 12-10-2018 VAPA_1c45460 1873e5078d9d55c7ba98241fffbff2cc 488 Pfam PF00675 Insulinase (Peptidase family M16) 69 208 2.1E-24 T 12-10-2018 IPR011765 Peptidase M16, N-terminal VAPA_1c45460 1873e5078d9d55c7ba98241fffbff2cc 488 ProSitePatterns PS00143 Insulinase family, zinc-binding region signature. 84 107 - T 12-10-2018 IPR001431 Peptidase M16, zinc-binding site GO:0004222|GO:0006508 VAPA_1c45460 1873e5078d9d55c7ba98241fffbff2cc 488 Pfam PF05193 Peptidase M16 inactive domain 218 401 3.6E-25 T 12-10-2018 IPR007863 Peptidase M16, C-terminal VAPA_1c45460 1873e5078d9d55c7ba98241fffbff2cc 488 Gene3D G3DSA:3.30.830.10 48 271 3.6E-78 T 12-10-2018 VAPA_1c42500 5e5abc230b4fa503c75db74a2fe29bbe 212 TIGRFAM TIGR04508 queE_Cx14CxxC: 7-carboxy-7-deazaguanine synthase 3 212 1.6E-100 T 12-10-2018 IPR030977 7-carboxy-7-deazaguanine synthase, Cx14CxxC-type GO:0008616|GO:0046872 KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 VAPA_1c42500 5e5abc230b4fa503c75db74a2fe29bbe 212 Hamap MF_00917 7-carboxy-7-deazaguanine synthase [queE]. 3 212 31.324 T 12-10-2018 IPR024924 7-carboxy-7-deazaguanine synthase-like KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 VAPA_1c42500 5e5abc230b4fa503c75db74a2fe29bbe 212 SUPERFAMILY SSF102114 46 138 3.14E-6 T 12-10-2018 VAPA_1c42500 5e5abc230b4fa503c75db74a2fe29bbe 212 Pfam PF13394 4Fe-4S single cluster domain 25 123 3.2E-6 T 12-10-2018 VAPA_1c42500 5e5abc230b4fa503c75db74a2fe29bbe 212 Gene3D G3DSA:3.20.20.70 2 212 2.3E-67 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 VAPA_1c20910 6ff32590fbc054e4886940df9b73d053 149 Pfam PF03960 ArsC family 13 120 4.7E-20 T 12-10-2018 IPR006660 Arsenate reductase-like VAPA_1c20910 6ff32590fbc054e4886940df9b73d053 149 TIGRFAM TIGR00014 arsC: arsenate reductase (glutaredoxin) 9 121 1.2E-41 T 12-10-2018 IPR006659 Arsenate reductase GO:0008794|GO:0055114 MetaCyc: PWY-4202|MetaCyc: PWY-4621 VAPA_1c20910 6ff32590fbc054e4886940df9b73d053 149 Gene3D G3DSA:3.40.30.10 7 146 1.2E-58 T 12-10-2018 VAPA_1c20910 6ff32590fbc054e4886940df9b73d053 149 SUPERFAMILY SSF52833 8 143 4.97E-40 T 12-10-2018 IPR036249 Thioredoxin-like superfamily VAPA_1c47660 54b9c6b8ec9b2ee5183092a920edf8dc 132 SMART SM00448 8 121 1.9E-35 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_1c47660 54b9c6b8ec9b2ee5183092a920edf8dc 132 Gene3D G3DSA:3.40.50.12740 7 132 4.2E-37 T 12-10-2018 VAPA_1c47660 54b9c6b8ec9b2ee5183092a920edf8dc 132 SUPERFAMILY SSF52172 6 124 1.04E-35 T 12-10-2018 IPR011006 CheY-like superfamily VAPA_1c47660 54b9c6b8ec9b2ee5183092a920edf8dc 132 Pfam PF00072 Response regulator receiver domain 10 122 2.3E-26 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_1c18460 237e20f4af8b9de74299f93b8cb3fcaf 106 Pfam PF00893 Small Multidrug Resistance protein 1 93 6.2E-30 T 12-10-2018 IPR000390 Small multidrug resistance protein family GO:0016021 VAPA_1c18460 237e20f4af8b9de74299f93b8cb3fcaf 106 SUPERFAMILY SSF103481 5 104 1.22E-20 T 12-10-2018 VAPA_1c18460 237e20f4af8b9de74299f93b8cb3fcaf 106 Gene3D G3DSA:1.10.3730.20 1 106 1.9E-33 T 12-10-2018 VAPA_1c53340 f3368a60787f61cbf090503beaca6786 222 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 8 196 2.7E-38 T 12-10-2018 IPR001303 Class II aldolase/adducin N-terminal VAPA_1c53340 f3368a60787f61cbf090503beaca6786 222 SUPERFAMILY SSF53639 2 219 2.35E-49 T 12-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily VAPA_1c53340 f3368a60787f61cbf090503beaca6786 222 SMART SM01007 8 196 8.1E-48 T 12-10-2018 IPR001303 Class II aldolase/adducin N-terminal VAPA_1c53340 f3368a60787f61cbf090503beaca6786 222 Gene3D G3DSA:3.40.225.10 1 221 3.6E-47 T 12-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily VAPA_2c11230 1ee6c3583b544d2ba35ac005b00588b4 304 SUPERFAMILY SSF53850 91 296 2.95E-37 T 12-10-2018 VAPA_2c11230 1ee6c3583b544d2ba35ac005b00588b4 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 2.0E-9 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_2c11230 1ee6c3583b544d2ba35ac005b00588b4 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 2.0E-9 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_2c11230 1ee6c3583b544d2ba35ac005b00588b4 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 2.0E-9 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_2c11230 1ee6c3583b544d2ba35ac005b00588b4 304 SUPERFAMILY SSF46785 3 112 6.98E-25 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_2c11230 1ee6c3583b544d2ba35ac005b00588b4 304 Pfam PF03466 LysR substrate binding domain 90 292 9.6E-38 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_2c11230 1ee6c3583b544d2ba35ac005b00588b4 304 Gene3D G3DSA:1.10.10.10 2 91 7.2E-26 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_2c11230 1ee6c3583b544d2ba35ac005b00588b4 304 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 6.8E-22 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_2c11230 1ee6c3583b544d2ba35ac005b00588b4 304 Gene3D G3DSA:3.40.190.290 92 298 5.4E-39 T 12-10-2018 VAPA_1c01650 f107a1f8650fae9eadaecc2f8d91b0e7 527 SMART SM00155 175 202 1.7 T 12-10-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 VAPA_1c01650 f107a1f8650fae9eadaecc2f8d91b0e7 527 SMART SM00155 416 443 1.7E-5 T 12-10-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 VAPA_1c01650 f107a1f8650fae9eadaecc2f8d91b0e7 527 SUPERFAMILY SSF56024 293 465 2.92E-30 T 12-10-2018 VAPA_1c01650 f107a1f8650fae9eadaecc2f8d91b0e7 527 Gene3D G3DSA:3.30.870.10 314 471 3.0E-29 T 12-10-2018 VAPA_1c01650 f107a1f8650fae9eadaecc2f8d91b0e7 527 Gene3D G3DSA:3.30.870.10 69 266 6.4E-34 T 12-10-2018 VAPA_1c01650 f107a1f8650fae9eadaecc2f8d91b0e7 527 Pfam PF13091 PLD-like domain 83 234 2.4E-13 T 12-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 VAPA_1c01650 f107a1f8650fae9eadaecc2f8d91b0e7 527 Pfam PF13091 PLD-like domain 329 466 1.7E-20 T 12-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 VAPA_1c01650 f107a1f8650fae9eadaecc2f8d91b0e7 527 SUPERFAMILY SSF56024 42 253 4.97E-36 T 12-10-2018 VAPA_1c05770 e123377e703c6b30e1bf88dd9a1bbb6d 345 Gene3D G3DSA:3.40.630.10 17 332 3.4E-50 T 12-10-2018 VAPA_1c05770 e123377e703c6b30e1bf88dd9a1bbb6d 345 SUPERFAMILY SSF53187 34 336 1.92E-55 T 12-10-2018 VAPA_1c05770 e123377e703c6b30e1bf88dd9a1bbb6d 345 Pfam PF04952 Succinylglutamate desuccinylase / Aspartoacylase family 35 320 2.3E-22 T 12-10-2018 IPR007036 Succinylglutamate desuccinylase/aspartoacylase GO:0016788 VAPA_1c54960 3d86370bf0b4b4799f3ab4f0ed087c43 309 PRINTS PR00169 Potassium channel signature 82 105 5.4E-33 T 12-10-2018 IPR028325 Voltage-gated potassium channel GO:0005249|GO:0006813|GO:0008076 Reactome: R-HSA-1296072 VAPA_1c54960 3d86370bf0b4b4799f3ab4f0ed087c43 309 PRINTS PR00169 Potassium channel signature 108 128 5.4E-33 T 12-10-2018 IPR028325 Voltage-gated potassium channel GO:0005249|GO:0006813|GO:0008076 Reactome: R-HSA-1296072 VAPA_1c54960 3d86370bf0b4b4799f3ab4f0ed087c43 309 PRINTS PR00169 Potassium channel signature 202 224 5.4E-33 T 12-10-2018 IPR028325 Voltage-gated potassium channel GO:0005249|GO:0006813|GO:0008076 Reactome: R-HSA-1296072 VAPA_1c54960 3d86370bf0b4b4799f3ab4f0ed087c43 309 PRINTS PR00169 Potassium channel signature 40 68 5.4E-33 T 12-10-2018 IPR028325 Voltage-gated potassium channel GO:0005249|GO:0006813|GO:0008076 Reactome: R-HSA-1296072 VAPA_1c54960 3d86370bf0b4b4799f3ab4f0ed087c43 309 PRINTS PR00169 Potassium channel signature 144 170 5.4E-33 T 12-10-2018 IPR028325 Voltage-gated potassium channel GO:0005249|GO:0006813|GO:0008076 Reactome: R-HSA-1296072 VAPA_1c54960 3d86370bf0b4b4799f3ab4f0ed087c43 309 PRINTS PR00169 Potassium channel signature 231 257 5.4E-33 T 12-10-2018 IPR028325 Voltage-gated potassium channel GO:0005249|GO:0006813|GO:0008076 Reactome: R-HSA-1296072 VAPA_1c54960 3d86370bf0b4b4799f3ab4f0ed087c43 309 PRINTS PR00169 Potassium channel signature 173 196 5.4E-33 T 12-10-2018 IPR028325 Voltage-gated potassium channel GO:0005249|GO:0006813|GO:0008076 Reactome: R-HSA-1296072 VAPA_1c54960 3d86370bf0b4b4799f3ab4f0ed087c43 309 SUPERFAMILY SSF81324 47 260 7.46E-49 T 12-10-2018 VAPA_1c54960 3d86370bf0b4b4799f3ab4f0ed087c43 309 Gene3D G3DSA:1.10.287.70 47 259 9.6E-54 T 12-10-2018 VAPA_1c54960 3d86370bf0b4b4799f3ab4f0ed087c43 309 Pfam PF00520 Ion transport protein 48 256 3.0E-24 T 12-10-2018 IPR005821 Ion transport domain GO:0005216|GO:0006811|GO:0016020|GO:0055085 VAPA_1c40250 27070666bc482b8f295cb212c5f0e900 327 Gene3D G3DSA:3.40.190.10 94 300 7.7E-59 T 12-10-2018 VAPA_1c40250 27070666bc482b8f295cb212c5f0e900 327 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 12 70 2.9E-17 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c40250 27070666bc482b8f295cb212c5f0e900 327 SUPERFAMILY SSF46785 8 89 1.51E-18 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c40250 27070666bc482b8f295cb212c5f0e900 327 Gene3D G3DSA:1.10.10.10 2 92 3.3E-25 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c40250 27070666bc482b8f295cb212c5f0e900 327 Pfam PF03466 LysR substrate binding domain 98 304 1.9E-22 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_1c40250 27070666bc482b8f295cb212c5f0e900 327 Gene3D G3DSA:3.40.190.10 176 275 7.7E-59 T 12-10-2018 VAPA_1c40250 27070666bc482b8f295cb212c5f0e900 327 SUPERFAMILY SSF53850 94 304 5.61E-38 T 12-10-2018 VAPA_1c40250 27070666bc482b8f295cb212c5f0e900 327 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 27 38 8.1E-5 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c40250 27070666bc482b8f295cb212c5f0e900 327 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 38 48 8.1E-5 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c40250 27070666bc482b8f295cb212c5f0e900 327 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 48 59 8.1E-5 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c10430 601e3670695e0099ba8f5813b4aff676 241 SUPERFAMILY SSF56925 22 241 1.36E-21 T 12-10-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel VAPA_1c10430 601e3670695e0099ba8f5813b4aff676 241 Gene3D G3DSA:2.40.160.20 19 241 2.7E-64 T 12-10-2018 VAPA_1c10430 601e3670695e0099ba8f5813b4aff676 241 Pfam PF03922 OmpW family 24 241 1.5E-28 T 12-10-2018 IPR005618 Outer membrane protein, OmpW GO:0019867 VAPA_1c27970 b00ecb3c0a0a34124129e5fc79bcf59a 489 TIGRFAM TIGR01302 IMP_dehydrog: inosine-5'-monophosphate dehydrogenase 7 456 9.7E-189 T 12-10-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 VAPA_1c27970 b00ecb3c0a0a34124129e5fc79bcf59a 489 ProSitePatterns PS00487 IMP dehydrogenase / GMP reductase signature. 293 305 - T 12-10-2018 IPR015875 IMP dehydrogenase / GMP reductase, conserved site GO:0016491|GO:0055114 VAPA_1c27970 b00ecb3c0a0a34124129e5fc79bcf59a 489 Gene3D G3DSA:3.20.20.70 1 488 5.2E-211 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 VAPA_1c27970 b00ecb3c0a0a34124129e5fc79bcf59a 489 Pfam PF00571 CBS domain 147 200 2.7E-7 T 12-10-2018 IPR000644 CBS domain VAPA_1c27970 b00ecb3c0a0a34124129e5fc79bcf59a 489 Pfam PF00571 CBS domain 94 138 5.5E-7 T 12-10-2018 IPR000644 CBS domain VAPA_1c27970 b00ecb3c0a0a34124129e5fc79bcf59a 489 PIRSF PIRSF000130 1 489 1.8E-200 T 12-10-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 VAPA_1c27970 b00ecb3c0a0a34124129e5fc79bcf59a 489 SUPERFAMILY SSF51412 4 479 5.76E-124 T 12-10-2018 VAPA_1c27970 b00ecb3c0a0a34124129e5fc79bcf59a 489 Hamap MF_01964 Inosine-5'-monophosphate dehydrogenase [guaB]. 7 488 83.807 T 12-10-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 VAPA_1c27970 b00ecb3c0a0a34124129e5fc79bcf59a 489 SMART SM01240 6 475 0.0 T 12-10-2018 VAPA_1c27970 b00ecb3c0a0a34124129e5fc79bcf59a 489 SMART SM00116 95 142 4.7E-9 T 12-10-2018 IPR000644 CBS domain VAPA_1c27970 b00ecb3c0a0a34124129e5fc79bcf59a 489 SMART SM00116 156 204 8.7E-8 T 12-10-2018 IPR000644 CBS domain VAPA_1c27970 b00ecb3c0a0a34124129e5fc79bcf59a 489 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 7 475 6.0E-162 T 12-10-2018 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 VAPA_1c27970 b00ecb3c0a0a34124129e5fc79bcf59a 489 SUPERFAMILY SSF54631 94 201 3.05E-27 T 12-10-2018 VAPA_1c15730 03e398bab3bd1db9d0c1285a12887ecd 115 SUPERFAMILY SSF55248 17 110 2.49E-28 T 12-10-2018 IPR036428 Pterin 4 alpha carbinolamine dehydratase superfamily GO:0006729|GO:0008124 KEGG: 00790+4.2.1.96|MetaCyc: PWY-7158 VAPA_1c15730 03e398bab3bd1db9d0c1285a12887ecd 115 Pfam PF01329 Pterin 4 alpha carbinolamine dehydratase 17 108 8.9E-26 T 12-10-2018 IPR001533 Pterin 4 alpha carbinolamine dehydratase GO:0006729|GO:0008124 KEGG: 00790+4.2.1.96|MetaCyc: PWY-7158 VAPA_1c15730 03e398bab3bd1db9d0c1285a12887ecd 115 Gene3D G3DSA:3.30.1360.20 17 114 3.1E-29 T 12-10-2018 IPR036428 Pterin 4 alpha carbinolamine dehydratase superfamily GO:0006729|GO:0008124 KEGG: 00790+4.2.1.96|MetaCyc: PWY-7158 VAPA_1c15730 03e398bab3bd1db9d0c1285a12887ecd 115 Hamap MF_00434 Putative pterin-4-alpha-carbinolamine dehydratase. 15 110 21.887 T 12-10-2018 IPR001533 Pterin 4 alpha carbinolamine dehydratase GO:0006729|GO:0008124 KEGG: 00790+4.2.1.96|MetaCyc: PWY-7158 VAPA_1c04540 c8491cf13bc5a94397553addf5249d11 251 Pfam PF07702 UTRA domain 105 239 6.5E-37 T 12-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 VAPA_1c04540 c8491cf13bc5a94397553addf5249d11 251 SMART SM00866 104 244 3.1E-31 T 12-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 VAPA_1c04540 c8491cf13bc5a94397553addf5249d11 251 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 42 56 4.6E-8 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_1c04540 c8491cf13bc5a94397553addf5249d11 251 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 56 72 4.6E-8 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_1c04540 c8491cf13bc5a94397553addf5249d11 251 Pfam PF00392 Bacterial regulatory proteins, gntR family 24 82 1.2E-16 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_1c04540 c8491cf13bc5a94397553addf5249d11 251 Gene3D G3DSA:3.40.1410.10 92 250 1.1E-42 T 12-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily VAPA_1c04540 c8491cf13bc5a94397553addf5249d11 251 SMART SM00345 23 82 3.2E-18 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_1c04540 c8491cf13bc5a94397553addf5249d11 251 Gene3D G3DSA:1.10.10.10 8 83 4.0E-22 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c04540 c8491cf13bc5a94397553addf5249d11 251 SUPERFAMILY SSF46785 11 91 1.84E-20 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c04540 c8491cf13bc5a94397553addf5249d11 251 SUPERFAMILY SSF64288 71 248 9.58E-45 T 12-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily VAPA_1c47370 b8754fc7bacf75a41ff6fdb5677bb2dc 1063 SUPERFAMILY SSF52467 28 246 1.5E-10 T 12-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily VAPA_1c47370 b8754fc7bacf75a41ff6fdb5677bb2dc 1063 Pfam PF13289 SIR2-like domain 149 270 1.8E-7 T 12-10-2018 IPR039444 SIR2-like domain VAPA_1c47370 b8754fc7bacf75a41ff6fdb5677bb2dc 1063 Gene3D G3DSA:3.30.420.10 816 1061 1.7E-38 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 VAPA_1c47370 b8754fc7bacf75a41ff6fdb5677bb2dc 1063 SUPERFAMILY SSF53098 596 1063 1.39E-62 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily VAPA_2c10590 a08114ed2ebb1a35905366f119377fe2 532 SUPERFAMILY SSF103473 22 410 4.19E-48 T 12-10-2018 IPR036259 MFS transporter superfamily VAPA_2c10590 a08114ed2ebb1a35905366f119377fe2 532 Pfam PF05977 Transmembrane secretion effector 15 530 3.8E-211 T 12-10-2018 IPR010290 Transmembrane secretion effector VAPA_2c10590 a08114ed2ebb1a35905366f119377fe2 532 Gene3D G3DSA:1.20.1250.20 17 407 4.5E-42 T 12-10-2018 VAPA_1c45080 595be056dec6067cba4a016310e4d54d 354 Pfam PF00633 Helix-hairpin-helix motif 107 136 5.2E-6 T 12-10-2018 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 VAPA_1c45080 595be056dec6067cba4a016310e4d54d 354 Gene3D G3DSA:3.90.79.10 236 353 9.1E-15 T 12-10-2018 VAPA_1c45080 595be056dec6067cba4a016310e4d54d 354 Gene3D G3DSA:1.10.340.30 29 140 2.5E-82 T 12-10-2018 VAPA_1c45080 595be056dec6067cba4a016310e4d54d 354 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 44 173 3.6E-16 T 12-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 VAPA_1c45080 595be056dec6067cba4a016310e4d54d 354 Pfam PF14815 NUDIX domain 247 349 1.5E-23 T 12-10-2018 IPR029119 MutY, C-terminal Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 VAPA_1c45080 595be056dec6067cba4a016310e4d54d 354 TIGRFAM TIGR01084 mutY: A/G-specific adenine glycosylase 14 284 5.4E-104 T 12-10-2018 IPR005760 A/G-specific adenine glycosylase MutY GO:0006284|GO:0019104 VAPA_1c45080 595be056dec6067cba4a016310e4d54d 354 SUPERFAMILY SSF48150 13 237 7.54E-69 T 12-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 VAPA_1c45080 595be056dec6067cba4a016310e4d54d 354 Gene3D G3DSA:1.10.1670.10 17 221 2.5E-82 T 12-10-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 VAPA_1c45080 595be056dec6067cba4a016310e4d54d 354 SUPERFAMILY SSF55811 232 349 1.9E-23 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 VAPA_1c45080 595be056dec6067cba4a016310e4d54d 354 SMART SM00478 47 202 1.2E-37 T 12-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 VAPA_1c46560 babb56244a90e377926d22429f0eec61 471 PRINTS PR01050 Pyruvate kinase family signature 266 290 4.7E-64 T 12-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 VAPA_1c46560 babb56244a90e377926d22429f0eec61 471 PRINTS PR01050 Pyruvate kinase family signature 214 240 4.7E-64 T 12-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 VAPA_1c46560 babb56244a90e377926d22429f0eec61 471 PRINTS PR01050 Pyruvate kinase family signature 291 309 4.7E-64 T 12-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 VAPA_1c46560 babb56244a90e377926d22429f0eec61 471 PRINTS PR01050 Pyruvate kinase family signature 241 265 4.7E-64 T 12-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 VAPA_1c46560 babb56244a90e377926d22429f0eec61 471 PRINTS PR01050 Pyruvate kinase family signature 62 78 4.7E-64 T 12-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 VAPA_1c46560 babb56244a90e377926d22429f0eec61 471 PRINTS PR01050 Pyruvate kinase family signature 187 201 4.7E-64 T 12-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 VAPA_1c46560 babb56244a90e377926d22429f0eec61 471 PRINTS PR01050 Pyruvate kinase family signature 310 326 4.7E-64 T 12-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 VAPA_1c46560 babb56244a90e377926d22429f0eec61 471 Gene3D G3DSA:2.40.33.10 73 169 3.9E-158 T 12-10-2018 IPR015806 Pyruvate kinase, insert domain superfamily GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 VAPA_1c46560 babb56244a90e377926d22429f0eec61 471 SUPERFAMILY SSF52935 320 470 2.35E-36 T 12-10-2018 IPR036918 Pyruvate kinase, C-terminal domain superfamily KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 VAPA_1c46560 babb56244a90e377926d22429f0eec61 471 SUPERFAMILY SSF50800 73 168 4.19E-22 T 12-10-2018 IPR011037 Pyruvate kinase-like, insert domain superfamily VAPA_1c46560 babb56244a90e377926d22429f0eec61 471 Gene3D G3DSA:3.40.1380.20 333 465 3.9E-158 T 12-10-2018 IPR036918 Pyruvate kinase, C-terminal domain superfamily KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 VAPA_1c46560 babb56244a90e377926d22429f0eec61 471 Pfam PF00224 Pyruvate kinase, barrel domain 5 335 7.4E-107 T 12-10-2018 IPR015793 Pyruvate kinase, barrel GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 VAPA_1c46560 babb56244a90e377926d22429f0eec61 471 SUPERFAMILY SSF51621 2 337 6.98E-92 T 12-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 VAPA_1c46560 babb56244a90e377926d22429f0eec61 471 Gene3D G3DSA:3.20.20.60 5 332 3.9E-158 T 12-10-2018 VAPA_1c46560 babb56244a90e377926d22429f0eec61 471 Pfam PF02887 Pyruvate kinase, alpha/beta domain 355 467 4.1E-27 T 12-10-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 VAPA_1c46560 babb56244a90e377926d22429f0eec61 471 TIGRFAM TIGR01064 pyruv_kin: pyruvate kinase 6 470 1.9E-144 T 12-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 VAPA_1c46290 b015fc3aefda9940d774b107c933f133 669 Pfam PF09977 Putative Tad-like Flp pilus-assembly 61 154 5.1E-9 T 12-10-2018 IPR018705 Domain of unknown function DUF2134, membrane VAPA_1c38470 d4d9c4b359baa6ef62b1c61b3de553f7 112 SUPERFAMILY SSF52821 4 110 5.89E-22 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily VAPA_1c38470 d4d9c4b359baa6ef62b1c61b3de553f7 112 Pfam PF00581 Rhodanese-like domain 11 103 2.8E-10 T 12-10-2018 IPR001763 Rhodanese-like domain VAPA_1c38470 d4d9c4b359baa6ef62b1c61b3de553f7 112 Gene3D G3DSA:3.40.250.10 3 103 5.2E-20 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily VAPA_1c38470 d4d9c4b359baa6ef62b1c61b3de553f7 112 SMART SM00450 8 107 2.3E-10 T 12-10-2018 IPR001763 Rhodanese-like domain VAPA_1c01310 9cb45b500e464daef5c3bd36e3f6e748 276 SUPERFAMILY SSF51621 8 261 2.2E-62 T 12-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 VAPA_1c01310 9cb45b500e464daef5c3bd36e3f6e748 276 Pfam PF13714 Phosphoenolpyruvate phosphomutase 12 249 5.6E-67 T 12-10-2018 VAPA_1c01310 9cb45b500e464daef5c3bd36e3f6e748 276 Gene3D G3DSA:3.20.20.60 1 231 6.4E-63 T 12-10-2018 VAPA_2c03870 1cbdf88b6ae1bd3b97f9038d1621c6ef 274 Pfam PF00582 Universal stress protein family 222 272 3.8E-5 T 12-10-2018 IPR006016 UspA VAPA_2c03870 1cbdf88b6ae1bd3b97f9038d1621c6ef 274 Gene3D G3DSA:3.40.50.12370 6 273 5.3E-26 T 12-10-2018 VAPA_2c03870 1cbdf88b6ae1bd3b97f9038d1621c6ef 274 PRINTS PR01438 Universal stress protein signature 252 274 2.5E-6 T 12-10-2018 IPR006015 Universal stress protein A VAPA_2c03870 1cbdf88b6ae1bd3b97f9038d1621c6ef 274 PRINTS PR01438 Universal stress protein signature 234 246 2.5E-6 T 12-10-2018 IPR006015 Universal stress protein A VAPA_2c03870 1cbdf88b6ae1bd3b97f9038d1621c6ef 274 PRINTS PR01438 Universal stress protein signature 4 22 2.5E-6 T 12-10-2018 IPR006015 Universal stress protein A VAPA_2c03870 1cbdf88b6ae1bd3b97f9038d1621c6ef 274 SUPERFAMILY SSF52402 1 145 3.52E-7 T 12-10-2018 VAPA_2c03870 1cbdf88b6ae1bd3b97f9038d1621c6ef 274 SUPERFAMILY SSF52402 155 273 5.27E-16 T 12-10-2018 VAPA_1c39280 74acbbc6442a4b28feefaab0667740ce 313 Gene3D G3DSA:3.40.190.10 178 278 2.9E-40 T 12-10-2018 VAPA_1c39280 74acbbc6442a4b28feefaab0667740ce 313 Gene3D G3DSA:1.10.10.10 17 105 3.6E-19 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c39280 74acbbc6442a4b28feefaab0667740ce 313 SUPERFAMILY SSF46785 13 124 2.45E-19 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c39280 74acbbc6442a4b28feefaab0667740ce 313 SUPERFAMILY SSF53850 105 308 6.52E-42 T 12-10-2018 VAPA_1c39280 74acbbc6442a4b28feefaab0667740ce 313 Pfam PF03466 LysR substrate binding domain 101 304 1.5E-45 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_1c39280 74acbbc6442a4b28feefaab0667740ce 313 Gene3D G3DSA:3.40.190.10 107 300 2.9E-40 T 12-10-2018 VAPA_1c39280 74acbbc6442a4b28feefaab0667740ce 313 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 20 79 5.6E-15 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c50690 1baac621fa091611580f992095ae496e 233 SMART SM00342 158 229 4.3E-9 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 VAPA_1c50690 1baac621fa091611580f992095ae496e 233 SUPERFAMILY SSF51182 15 161 8.54E-10 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily VAPA_1c50690 1baac621fa091611580f992095ae496e 233 Gene3D G3DSA:2.60.120.10 11 78 4.1E-8 T 12-10-2018 IPR014710 RmlC-like jelly roll fold VAPA_1c50690 1baac621fa091611580f992095ae496e 233 Pfam PF12833 Helix-turn-helix domain 164 230 3.3E-14 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 VAPA_1c50690 1baac621fa091611580f992095ae496e 233 Pfam PF07883 Cupin domain 15 73 2.5E-7 T 12-10-2018 IPR013096 Cupin 2, conserved barrel VAPA_1c50690 1baac621fa091611580f992095ae496e 233 Gene3D G3DSA:1.10.10.60 145 231 7.4E-17 T 12-10-2018 VAPA_1c04240 6986c76c18d4574204e35a5c5cb19be0 454 Pfam PF12831 FAD dependent oxidoreductase 24 445 6.4E-109 T 12-10-2018 IPR039649 Digeranylgeranylglycerophospholipid reductase, N-terminal VAPA_1c04240 6986c76c18d4574204e35a5c5cb19be0 454 SUPERFAMILY SSF51905 2 425 1.28E-27 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c04240 6986c76c18d4574204e35a5c5cb19be0 454 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 57 72 2.4E-6 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 VAPA_1c04240 6986c76c18d4574204e35a5c5cb19be0 454 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 24 46 2.4E-6 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 VAPA_1c04240 6986c76c18d4574204e35a5c5cb19be0 454 Gene3D G3DSA:3.50.50.60 21 219 3.7E-18 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c45300 5da43c9e0f468ab09dfb5d3396b18345 289 Pfam PF03466 LysR substrate binding domain 90 259 9.8E-24 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_1c45300 5da43c9e0f468ab09dfb5d3396b18345 289 SUPERFAMILY SSF46785 4 111 1.25E-24 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c45300 5da43c9e0f468ab09dfb5d3396b18345 289 Gene3D G3DSA:3.40.190.10 97 264 2.7E-33 T 12-10-2018 VAPA_1c45300 5da43c9e0f468ab09dfb5d3396b18345 289 Gene3D G3DSA:3.40.190.10 169 262 2.7E-33 T 12-10-2018 VAPA_1c45300 5da43c9e0f468ab09dfb5d3396b18345 289 Gene3D G3DSA:1.10.10.10 1 86 1.0E-25 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c45300 5da43c9e0f468ab09dfb5d3396b18345 289 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 32 42 2.1E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c45300 5da43c9e0f468ab09dfb5d3396b18345 289 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 21 32 2.1E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c45300 5da43c9e0f468ab09dfb5d3396b18345 289 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 53 2.1E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c45300 5da43c9e0f468ab09dfb5d3396b18345 289 SUPERFAMILY SSF53850 90 287 9.62E-23 T 12-10-2018 VAPA_1c45300 5da43c9e0f468ab09dfb5d3396b18345 289 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 64 1.6E-18 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c37580 dff3cdc50e3aeacf5adb8edcad0ff86c 155 Gene3D G3DSA:3.30.1490.190 96 155 1.9E-5 T 12-10-2018 VAPA_1c37580 dff3cdc50e3aeacf5adb8edcad0ff86c 155 SUPERFAMILY SSF46785 17 152 4.77E-18 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c37580 dff3cdc50e3aeacf5adb8edcad0ff86c 155 Gene3D G3DSA:1.10.10.10 13 94 3.5E-12 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c37580 dff3cdc50e3aeacf5adb8edcad0ff86c 155 Pfam PF01475 Ferric uptake regulator family 23 146 3.8E-7 T 12-10-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 VAPA_2c07700 e5102fa331ecf6bcfd42c700e2007429 202 SMART SM00448 4 116 7.9E-23 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_2c07700 e5102fa331ecf6bcfd42c700e2007429 202 Gene3D G3DSA:3.40.50.2300 3 124 1.1E-24 T 12-10-2018 VAPA_2c07700 e5102fa331ecf6bcfd42c700e2007429 202 SUPERFAMILY SSF52172 4 126 6.55E-26 T 12-10-2018 IPR011006 CheY-like superfamily VAPA_2c07700 e5102fa331ecf6bcfd42c700e2007429 202 Gene3D G3DSA:1.10.10.10 125 200 2.0E-19 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_2c07700 e5102fa331ecf6bcfd42c700e2007429 202 SUPERFAMILY SSF46894 126 201 5.1E-18 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 VAPA_2c07700 e5102fa331ecf6bcfd42c700e2007429 202 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 141 155 2.4E-8 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_2c07700 e5102fa331ecf6bcfd42c700e2007429 202 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 155 171 2.4E-8 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_2c07700 e5102fa331ecf6bcfd42c700e2007429 202 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 171 183 2.4E-8 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_2c07700 e5102fa331ecf6bcfd42c700e2007429 202 SMART SM00421 138 195 2.8E-15 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_2c07700 e5102fa331ecf6bcfd42c700e2007429 202 Pfam PF00072 Response regulator receiver domain 7 116 2.4E-19 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_2c07700 e5102fa331ecf6bcfd42c700e2007429 202 Pfam PF00196 Bacterial regulatory proteins, luxR family 140 192 3.5E-14 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_1c16300 379417eb53daec005ac4bd4262f4565a 325 TIGRFAM TIGR01306 GMP_reduct_2: guanosine monophosphate reductase 3 313 4.6E-163 T 12-10-2018 IPR005994 Guanosine monophosphate reductase, type2 GO:0003920|GO:0006163|GO:1902560 KEGG: 00230+1.7.1.7 VAPA_1c16300 379417eb53daec005ac4bd4262f4565a 325 Hamap MF_01511 GMP reductase [guaC]. 1 323 64.379 T 12-10-2018 IPR005994 Guanosine monophosphate reductase, type2 GO:0003920|GO:0006163|GO:1902560 KEGG: 00230+1.7.1.7 VAPA_1c16300 379417eb53daec005ac4bd4262f4565a 325 Gene3D G3DSA:3.20.20.70 1 319 1.0E-91 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 VAPA_1c16300 379417eb53daec005ac4bd4262f4565a 325 PIRSF PIRSF036500 1 318 5.4E-168 T 12-10-2018 IPR005994 Guanosine monophosphate reductase, type2 GO:0003920|GO:0006163|GO:1902560 KEGG: 00230+1.7.1.7 VAPA_1c16300 379417eb53daec005ac4bd4262f4565a 325 ProSitePatterns PS00487 IMP dehydrogenase / GMP reductase signature. 163 175 - T 12-10-2018 IPR015875 IMP dehydrogenase / GMP reductase, conserved site GO:0016491|GO:0055114 VAPA_1c16300 379417eb53daec005ac4bd4262f4565a 325 SMART SM01240 2 322 1.1E-92 T 12-10-2018 VAPA_1c16300 379417eb53daec005ac4bd4262f4565a 325 SUPERFAMILY SSF51412 3 311 1.96E-86 T 12-10-2018 VAPA_1c16300 379417eb53daec005ac4bd4262f4565a 325 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 5 308 1.1E-60 T 12-10-2018 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 VAPA_2c10930 d315758f6deb44549a507fab5285ec13 539 SUPERFAMILY SSF56024 50 269 8.3E-43 T 12-10-2018 VAPA_2c10930 d315758f6deb44549a507fab5285ec13 539 SMART SM00155 425 452 2.9E-7 T 12-10-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 VAPA_2c10930 d315758f6deb44549a507fab5285ec13 539 SMART SM00155 186 213 0.0033 T 12-10-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 VAPA_2c10930 d315758f6deb44549a507fab5285ec13 539 SUPERFAMILY SSF56024 306 476 6.06E-35 T 12-10-2018 VAPA_2c10930 d315758f6deb44549a507fab5285ec13 539 Pfam PF13091 PLD-like domain 338 478 2.9E-21 T 12-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 VAPA_2c10930 d315758f6deb44549a507fab5285ec13 539 Pfam PF13091 PLD-like domain 96 245 1.1E-15 T 12-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 VAPA_2c10930 d315758f6deb44549a507fab5285ec13 539 Gene3D G3DSA:3.30.870.10 307 488 4.0E-34 T 12-10-2018 VAPA_2c10930 d315758f6deb44549a507fab5285ec13 539 Gene3D G3DSA:3.30.870.10 75 267 2.3E-36 T 12-10-2018 VAPA_1c15920 51adde4fc65812db47a24a8e5120ce57 388 Gene3D G3DSA:3.40.50.2300 144 383 4.7E-105 T 12-10-2018 VAPA_1c15920 51adde4fc65812db47a24a8e5120ce57 388 Pfam PF13458 Periplasmic binding protein 30 356 7.9E-58 T 12-10-2018 IPR028081 Leucine-binding protein domain VAPA_1c15920 51adde4fc65812db47a24a8e5120ce57 388 Gene3D G3DSA:3.40.50.2300 31 372 4.7E-105 T 12-10-2018 VAPA_1c15920 51adde4fc65812db47a24a8e5120ce57 388 SUPERFAMILY SSF53822 29 387 3.14E-70 T 12-10-2018 IPR028082 Periplasmic binding protein-like I VAPA_1c51390 eef77997990af49546f648988b813e34 302 Gene3D G3DSA:3.40.190.10 104 290 1.7E-48 T 12-10-2018 VAPA_1c51390 eef77997990af49546f648988b813e34 302 Gene3D G3DSA:3.40.190.10 164 263 1.7E-48 T 12-10-2018 VAPA_1c51390 eef77997990af49546f648988b813e34 302 Gene3D G3DSA:1.10.10.10 7 92 6.0E-19 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c51390 eef77997990af49546f648988b813e34 302 SUPERFAMILY SSF53850 94 293 2.71E-34 T 12-10-2018 VAPA_1c51390 eef77997990af49546f648988b813e34 302 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 9 67 4.6E-18 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c51390 eef77997990af49546f648988b813e34 302 Pfam PF03466 LysR substrate binding domain 93 292 6.2E-34 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_1c51390 eef77997990af49546f648988b813e34 302 SUPERFAMILY SSF46785 5 84 1.97E-18 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c20060 ec28f9c2583043c981fe5a6e3e4a6ffa 401 TIGRFAM TIGR00937 2A51: chromate efflux transporter 18 394 9.9E-104 T 12-10-2018 IPR014047 Chromate transporter, long chain VAPA_1c20060 ec28f9c2583043c981fe5a6e3e4a6ffa 401 Pfam PF02417 Chromate transporter 230 395 1.4E-38 T 12-10-2018 IPR003370 Chromate transporter GO:0015109|GO:0015703 VAPA_1c20060 ec28f9c2583043c981fe5a6e3e4a6ffa 401 Pfam PF02417 Chromate transporter 14 177 1.9E-33 T 12-10-2018 IPR003370 Chromate transporter GO:0015109|GO:0015703 VAPA_1c20060 ec28f9c2583043c981fe5a6e3e4a6ffa 401 PIRSF PIRSF004810 2 401 2.4E-132 T 12-10-2018 IPR014047 Chromate transporter, long chain VAPA_1c03410 f267d72f582278028b8bf2257c39dc90 227 Gene3D G3DSA:3.40.50.2020 8 227 9.8E-66 T 12-10-2018 VAPA_1c03410 f267d72f582278028b8bf2257c39dc90 227 Hamap MF_01208 Orotate phosphoribosyltransferase [pyrE]. 1 227 30.744 T 12-10-2018 IPR023031 Orotate phosphoribosyltransferase GO:0004588|GO:0006221 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 VAPA_1c03410 f267d72f582278028b8bf2257c39dc90 227 TIGRFAM TIGR00336 pyrE: orotate phosphoribosyltransferase 18 198 4.3E-53 T 12-10-2018 IPR004467 Orotate phosphoribosyl transferase domain GO:0004588 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 VAPA_1c03410 f267d72f582278028b8bf2257c39dc90 227 Pfam PF00156 Phosphoribosyl transferase domain 47 166 8.9E-14 T 12-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 VAPA_1c03410 f267d72f582278028b8bf2257c39dc90 227 SUPERFAMILY SSF53271 11 205 1.15E-41 T 12-10-2018 IPR029057 Phosphoribosyltransferase-like VAPA_1c21910 e5e2c43116d81882082ce5141819d793 336 ProSitePatterns PS00356 LacI-type HTH domain signature. 5 23 - T 12-10-2018 VAPA_1c21910 e5e2c43116d81882082ce5141819d793 336 SMART SM00354 2 72 8.6E-16 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 VAPA_1c21910 e5e2c43116d81882082ce5141819d793 336 SUPERFAMILY SSF53822 61 331 1.81E-63 T 12-10-2018 IPR028082 Periplasmic binding protein-like I VAPA_1c21910 e5e2c43116d81882082ce5141819d793 336 Gene3D G3DSA:1.10.260.40 1 56 6.3E-17 T 12-10-2018 VAPA_1c21910 e5e2c43116d81882082ce5141819d793 336 Pfam PF13377 Periplasmic binding protein-like domain 170 330 9.3E-31 T 12-10-2018 VAPA_1c21910 e5e2c43116d81882082ce5141819d793 336 Pfam PF00356 Bacterial regulatory proteins, lacI family 4 49 2.3E-10 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 VAPA_1c21910 e5e2c43116d81882082ce5141819d793 336 SUPERFAMILY SSF47413 2 60 1.03E-13 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 VAPA_1c21910 e5e2c43116d81882082ce5141819d793 336 Gene3D G3DSA:3.40.50.2300 57 307 1.9E-64 T 12-10-2018 VAPA_1c21910 e5e2c43116d81882082ce5141819d793 336 Gene3D G3DSA:3.40.50.2300 161 290 1.9E-64 T 12-10-2018 VAPA_1c13040 f98142d6d685820f02a547f3e92b48cd 267 Gene3D G3DSA:3.90.226.10 1 208 1.9E-66 T 12-10-2018 VAPA_1c13040 f98142d6d685820f02a547f3e92b48cd 267 Gene3D G3DSA:1.10.12.10 210 267 1.2E-18 T 12-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal VAPA_1c13040 f98142d6d685820f02a547f3e92b48cd 267 Pfam PF00378 Enoyl-CoA hydratase/isomerase 13 267 3.6E-60 T 12-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 VAPA_1c13040 f98142d6d685820f02a547f3e92b48cd 267 SUPERFAMILY SSF52096 4 267 2.23E-79 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily VAPA_1c13040 f98142d6d685820f02a547f3e92b48cd 267 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 108 128 - T 12-10-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824 VAPA_1c25600 102287d2bf6d8e14319d6b43b4b7f9a3 152 SUPERFAMILY SSF46955 15 138 2.38E-20 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily VAPA_1c25600 102287d2bf6d8e14319d6b43b4b7f9a3 152 Gene3D G3DSA:1.10.1660.10 55 142 5.0E-17 T 12-10-2018 VAPA_1c25600 102287d2bf6d8e14319d6b43b4b7f9a3 152 Pfam PF09278 MerR, DNA binding 56 120 1.3E-11 T 12-10-2018 IPR015358 Transcription regulator MerR, DNA binding VAPA_1c47630 8ec67751b34231af64dc22755fedebb8 770 SMART SM00283 507 768 1.2E-79 T 12-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 VAPA_1c47630 8ec67751b34231af64dc22755fedebb8 770 Pfam PF13675 Type IV pili methyl-accepting chemotaxis transducer N-term 258 355 2.5E-8 T 12-10-2018 IPR029095 NarX-like, N-terminal VAPA_1c47630 8ec67751b34231af64dc22755fedebb8 770 Pfam PF13675 Type IV pili methyl-accepting chemotaxis transducer N-term 124 227 4.4E-15 T 12-10-2018 IPR029095 NarX-like, N-terminal VAPA_1c47630 8ec67751b34231af64dc22755fedebb8 770 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 552 735 4.1E-40 T 12-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 VAPA_1c47630 8ec67751b34231af64dc22755fedebb8 770 Gene3D G3DSA:1.10.287.950 441 770 2.5E-61 T 12-10-2018 VAPA_1c47630 8ec67751b34231af64dc22755fedebb8 770 SUPERFAMILY SSF58104 468 769 1.29E-62 T 12-10-2018 VAPA_1c13410 b1431fa94bd9b82e25fec131e6fff216 393 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 121 3.6E-22 T 12-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 VAPA_1c13410 b1431fa94bd9b82e25fec131e6fff216 393 Gene3D G3DSA:1.20.140.10 235 393 4.4E-34 T 12-10-2018 VAPA_1c13410 b1431fa94bd9b82e25fec131e6fff216 393 SUPERFAMILY SSF47203 231 393 7.78E-18 T 12-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 VAPA_1c13410 b1431fa94bd9b82e25fec131e6fff216 393 SUPERFAMILY SSF56645 2 244 1.23E-75 T 12-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 VAPA_1c13410 b1431fa94bd9b82e25fec131e6fff216 393 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 231 391 8.3E-19 T 12-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 VAPA_1c13410 b1431fa94bd9b82e25fec131e6fff216 393 Gene3D G3DSA:2.40.110.10 125 234 1.2E-35 T 12-10-2018 VAPA_1c13410 b1431fa94bd9b82e25fec131e6fff216 393 Gene3D G3DSA:1.10.540.10 2 120 4.7E-29 T 12-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 VAPA_1c13410 b1431fa94bd9b82e25fec131e6fff216 393 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 127 219 6.8E-19 T 12-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 VAPA_2c05070 c4730d7395e792441bbbacac6b705db1 277 Gene3D G3DSA:3.30.1450.10 55 131 9.7E-7 T 12-10-2018 IPR037873 BamE-like VAPA_2c05070 c4730d7395e792441bbbacac6b705db1 277 SUPERFAMILY SSF103088 157 273 5.23E-28 T 12-10-2018 IPR036737 OmpA-like domain superfamily VAPA_2c05070 c4730d7395e792441bbbacac6b705db1 277 Gene3D G3DSA:3.30.1330.60 142 277 2.6E-37 T 12-10-2018 IPR036737 OmpA-like domain superfamily VAPA_2c05070 c4730d7395e792441bbbacac6b705db1 277 Pfam PF00691 OmpA family 174 253 2.0E-18 T 12-10-2018 IPR006665 OmpA-like domain VAPA_2c05070 c4730d7395e792441bbbacac6b705db1 277 Pfam PF04355 SmpA / OmlA family 55 123 1.6E-16 T 12-10-2018 IPR007450 Lipoprotein SmpA/OmlA GO:0019867 VAPA_1c20390 dbe8c5a60d1ff5f3cb92d48703863e41 107 Gene3D G3DSA:2.102.10.10 5 107 3.9E-34 T 12-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 VAPA_1c20390 dbe8c5a60d1ff5f3cb92d48703863e41 107 Pfam PF00355 Rieske [2Fe-2S] domain 7 94 1.3E-18 T 12-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 VAPA_1c20390 dbe8c5a60d1ff5f3cb92d48703863e41 107 SUPERFAMILY SSF50022 7 106 3.14E-31 T 12-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 VAPA_1c05190 51b660e12196ff45b186174044123074 76 Pfam PF14375 Cysteine-rich CWC 12 66 1.5E-12 T 12-10-2018 IPR032720 Cysteine-rich CWC VAPA_1c28610 6ed0923596c40c01baa7ca0fbcde9f8c 305 SUPERFAMILY SSF102886 8 305 7.06E-126 T 12-10-2018 IPR036406 Oxygen-dependent coproporphyrinogen III oxidase superfamily GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 VAPA_1c28610 6ed0923596c40c01baa7ca0fbcde9f8c 305 Hamap MF_00333 Oxygen-dependent coproporphyrinogen-III oxidase [hemF]. 3 280 51.867 T 12-10-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 VAPA_1c28610 6ed0923596c40c01baa7ca0fbcde9f8c 305 Gene3D G3DSA:3.40.1500.10 1 305 9.0E-124 T 12-10-2018 IPR036406 Oxygen-dependent coproporphyrinogen III oxidase superfamily GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 VAPA_1c28610 6ed0923596c40c01baa7ca0fbcde9f8c 305 PRINTS PR00073 Coprogen oxidase signature 265 291 3.2E-69 T 12-10-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 VAPA_1c28610 6ed0923596c40c01baa7ca0fbcde9f8c 305 PRINTS PR00073 Coprogen oxidase signature 93 117 3.2E-69 T 12-10-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 VAPA_1c28610 6ed0923596c40c01baa7ca0fbcde9f8c 305 PRINTS PR00073 Coprogen oxidase signature 237 264 3.2E-69 T 12-10-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 VAPA_1c28610 6ed0923596c40c01baa7ca0fbcde9f8c 305 PRINTS PR00073 Coprogen oxidase signature 128 150 3.2E-69 T 12-10-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 VAPA_1c28610 6ed0923596c40c01baa7ca0fbcde9f8c 305 PRINTS PR00073 Coprogen oxidase signature 51 72 3.2E-69 T 12-10-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 VAPA_1c28610 6ed0923596c40c01baa7ca0fbcde9f8c 305 PRINTS PR00073 Coprogen oxidase signature 165 194 3.2E-69 T 12-10-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 VAPA_1c28610 6ed0923596c40c01baa7ca0fbcde9f8c 305 ProSitePatterns PS01021 Coproporphyrinogen III oxidase signature. 169 193 - T 12-10-2018 IPR018375 Coproporphyrinogen III oxidase, conserved site GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 VAPA_1c28610 6ed0923596c40c01baa7ca0fbcde9f8c 305 PIRSF PIRSF000166 1 305 6.1E-114 T 12-10-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 VAPA_1c28610 6ed0923596c40c01baa7ca0fbcde9f8c 305 Pfam PF01218 Coproporphyrinogen III oxidase 10 305 1.1E-119 T 12-10-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 VAPA_1c08150 074ffe50539482be08f01127f0e1293f 296 Pfam PF04321 RmlD substrate binding domain 1 294 1.1E-107 T 12-10-2018 IPR029903 RmlD-like substrate binding domain Reactome: R-HSA-156581|Reactome: R-HSA-5689880 VAPA_1c08150 074ffe50539482be08f01127f0e1293f 296 Gene3D G3DSA:3.90.25.10 162 289 1.9E-112 T 12-10-2018 VAPA_1c08150 074ffe50539482be08f01127f0e1293f 296 Gene3D G3DSA:3.40.50.720 4 282 1.9E-112 T 12-10-2018 VAPA_1c08150 074ffe50539482be08f01127f0e1293f 296 SUPERFAMILY SSF51735 1 294 4.12E-100 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c08150 074ffe50539482be08f01127f0e1293f 296 TIGRFAM TIGR01214 rmlD: dTDP-4-dehydrorhamnose reductase 2 294 3.7E-97 T 12-10-2018 IPR005913 dTDP-4-dehydrorhamnose reductase family Reactome: R-HSA-156581|Reactome: R-HSA-5689880 VAPA_2c00690 074ffe50539482be08f01127f0e1293f 296 Pfam PF04321 RmlD substrate binding domain 1 294 1.1E-107 T 12-10-2018 IPR029903 RmlD-like substrate binding domain Reactome: R-HSA-156581|Reactome: R-HSA-5689880 VAPA_2c00690 074ffe50539482be08f01127f0e1293f 296 Gene3D G3DSA:3.90.25.10 162 289 1.9E-112 T 12-10-2018 VAPA_2c00690 074ffe50539482be08f01127f0e1293f 296 Gene3D G3DSA:3.40.50.720 4 282 1.9E-112 T 12-10-2018 VAPA_2c00690 074ffe50539482be08f01127f0e1293f 296 SUPERFAMILY SSF51735 1 294 4.12E-100 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_2c00690 074ffe50539482be08f01127f0e1293f 296 TIGRFAM TIGR01214 rmlD: dTDP-4-dehydrorhamnose reductase 2 294 3.7E-97 T 12-10-2018 IPR005913 dTDP-4-dehydrorhamnose reductase family Reactome: R-HSA-156581|Reactome: R-HSA-5689880 VAPA_1c48860 d2534ecd08dc30e2ac703b7861ee8bd8 132 SMART SM00422 6 73 1.6E-18 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 VAPA_1c48860 d2534ecd08dc30e2ac703b7861ee8bd8 132 Gene3D G3DSA:1.10.1660.10 5 132 3.1E-27 T 12-10-2018 VAPA_1c48860 d2534ecd08dc30e2ac703b7861ee8bd8 132 SUPERFAMILY SSF46955 6 115 6.59E-25 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily VAPA_1c48860 d2534ecd08dc30e2ac703b7861ee8bd8 132 Pfam PF13411 MerR HTH family regulatory protein 6 71 7.1E-15 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 VAPA_1c25000 2ffba21ffdc4b5669ab32a285e6a6d94 112 ProSitePatterns PS00638 P-II protein C-terminal region signature. 83 96 - T 12-10-2018 IPR017918 Nitrogen regulatory protein PII, conserved site GO:0006808|GO:0030234 VAPA_1c25000 2ffba21ffdc4b5669ab32a285e6a6d94 112 SMART SM00938 4 105 1.7E-64 T 12-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 VAPA_1c25000 2ffba21ffdc4b5669ab32a285e6a6d94 112 PRINTS PR00340 P-II protein signature 2 17 2.1E-42 T 12-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 VAPA_1c25000 2ffba21ffdc4b5669ab32a285e6a6d94 112 PRINTS PR00340 P-II protein signature 23 41 2.1E-42 T 12-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 VAPA_1c25000 2ffba21ffdc4b5669ab32a285e6a6d94 112 PRINTS PR00340 P-II protein signature 52 75 2.1E-42 T 12-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 VAPA_1c25000 2ffba21ffdc4b5669ab32a285e6a6d94 112 PRINTS PR00340 P-II protein signature 83 103 2.1E-42 T 12-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 VAPA_1c25000 2ffba21ffdc4b5669ab32a285e6a6d94 112 Pfam PF00543 Nitrogen regulatory protein P-II 4 105 1.5E-42 T 12-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 VAPA_1c25000 2ffba21ffdc4b5669ab32a285e6a6d94 112 Gene3D G3DSA:3.30.70.120 1 112 8.1E-46 T 12-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal VAPA_1c25000 2ffba21ffdc4b5669ab32a285e6a6d94 112 SUPERFAMILY SSF54913 1 112 6.67E-45 T 12-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta VAPA_1c25000 2ffba21ffdc4b5669ab32a285e6a6d94 112 ProSitePatterns PS00496 P-II protein uridylation site. 46 51 - T 12-10-2018 IPR002332 Nitrogen regulatory protein P-II, urydylation site GO:0006808|GO:0030234 VAPA_1c25000 2ffba21ffdc4b5669ab32a285e6a6d94 112 PIRSF PIRSF039144 1 112 2.9E-54 T 12-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 VAPA_1c06520 ddf406447ea72b4bef81586022de518a 324 SUPERFAMILY SSF52980 29 209 2.31E-14 T 12-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 VAPA_1c06520 ddf406447ea72b4bef81586022de518a 324 Pfam PF08722 TnsA endonuclease N terminal 98 209 2.3E-8 T 12-10-2018 IPR014833 TnsA endonuclease, N-terminal VAPA_1c06520 ddf406447ea72b4bef81586022de518a 324 Gene3D G3DSA:3.40.1350.10 27 213 2.3E-28 T 12-10-2018 IPR011856 tRNA endonuclease-like domain superfamily GO:0003676|GO:0004518 VAPA_1c06180 07f542a3b1b74a057989d4c72939a723 294 SUPERFAMILY SSF69322 40 238 4.97E-6 T 12-10-2018 VAPA_1c50880 23edb47d5353d170b9fe51b47e8a71e6 138 PRINTS PR00060 Ribosomal protein L16 signature 24 36 1.9E-38 T 12-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 VAPA_1c50880 23edb47d5353d170b9fe51b47e8a71e6 138 PRINTS PR00060 Ribosomal protein L16 signature 88 117 1.9E-38 T 12-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 VAPA_1c50880 23edb47d5353d170b9fe51b47e8a71e6 138 PRINTS PR00060 Ribosomal protein L16 signature 58 87 1.9E-38 T 12-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 VAPA_1c50880 23edb47d5353d170b9fe51b47e8a71e6 138 PRINTS PR00060 Ribosomal protein L16 signature 42 53 1.9E-38 T 12-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 VAPA_1c50880 23edb47d5353d170b9fe51b47e8a71e6 138 SUPERFAMILY SSF54686 1 134 1.13E-52 T 12-10-2018 IPR036920 Ribosomal protein L10e/L16 superfamily GO:0003735|GO:0005840|GO:0006412 VAPA_1c50880 23edb47d5353d170b9fe51b47e8a71e6 138 Gene3D G3DSA:3.90.1170.10 1 137 4.2E-54 T 12-10-2018 IPR036920 Ribosomal protein L10e/L16 superfamily GO:0003735|GO:0005840|GO:0006412 VAPA_1c50880 23edb47d5353d170b9fe51b47e8a71e6 138 TIGRFAM TIGR01164 rplP_bact: ribosomal protein uL16 2 126 5.5E-58 T 12-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 VAPA_1c50880 23edb47d5353d170b9fe51b47e8a71e6 138 ProSitePatterns PS00586 Ribosomal protein L16 signature 1. 59 70 - T 12-10-2018 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 VAPA_1c50880 23edb47d5353d170b9fe51b47e8a71e6 138 Pfam PF00252 Ribosomal protein L16p/L10e 4 132 1.1E-47 T 12-10-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 VAPA_1c50880 23edb47d5353d170b9fe51b47e8a71e6 138 Hamap MF_01342 50S ribosomal protein L16 [rplP]. 1 134 37.923 T 12-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 VAPA_1c09020 3f88504e49a042fdc14bc4c0de5c9863 380 Gene3D G3DSA:1.10.540.10 1 116 7.5E-23 T 12-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 VAPA_1c09020 3f88504e49a042fdc14bc4c0de5c9863 380 Gene3D G3DSA:1.20.140.10 230 377 3.1E-29 T 12-10-2018 VAPA_1c09020 3f88504e49a042fdc14bc4c0de5c9863 380 SUPERFAMILY SSF47203 226 371 2.9E-33 T 12-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 VAPA_1c09020 3f88504e49a042fdc14bc4c0de5c9863 380 SUPERFAMILY SSF56645 1 224 1.57E-44 T 12-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 VAPA_1c09020 3f88504e49a042fdc14bc4c0de5c9863 380 Gene3D G3DSA:2.40.110.10 119 229 1.8E-20 T 12-10-2018 VAPA_1c09020 3f88504e49a042fdc14bc4c0de5c9863 380 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 108 9.4E-14 T 12-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 VAPA_1c09020 3f88504e49a042fdc14bc4c0de5c9863 380 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 226 353 3.8E-21 T 12-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 VAPA_1c09020 3f88504e49a042fdc14bc4c0de5c9863 380 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 120 212 2.9E-13 T 12-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 VAPA_2c00760 3d933e1995f09fede271599d6eac2884 299 Gene3D G3DSA:1.10.10.10 2 92 2.6E-21 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_2c00760 3d933e1995f09fede271599d6eac2884 299 Gene3D G3DSA:3.40.190.10 273 291 9.2E-8 T 12-10-2018 VAPA_2c00760 3d933e1995f09fede271599d6eac2884 299 SUPERFAMILY SSF53850 92 296 1.48E-14 T 12-10-2018 VAPA_2c00760 3d933e1995f09fede271599d6eac2884 299 SUPERFAMILY SSF46785 2 111 5.99E-19 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_2c00760 3d933e1995f09fede271599d6eac2884 299 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 62 5.6E-18 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_2c00760 3d933e1995f09fede271599d6eac2884 299 Gene3D G3DSA:3.40.190.10 195 272 9.2E-8 T 12-10-2018 VAPA_2c00760 3d933e1995f09fede271599d6eac2884 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 2.4E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_2c00760 3d933e1995f09fede271599d6eac2884 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 2.4E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_2c00760 3d933e1995f09fede271599d6eac2884 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 2.4E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_2c00760 3d933e1995f09fede271599d6eac2884 299 Pfam PF03466 LysR substrate binding domain 90 295 6.4E-19 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_1c13780 4c06209c399d868e89358fa9842cbc3c 301 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 89 100 3.4E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c13780 4c06209c399d868e89358fa9842cbc3c 301 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 162 181 3.4E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c13780 4c06209c399d868e89358fa9842cbc3c 301 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 142 150 3.4E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c13780 4c06209c399d868e89358fa9842cbc3c 301 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 5 201 3.4E-7 T 12-10-2018 VAPA_1c13780 4c06209c399d868e89358fa9842cbc3c 301 Gene3D G3DSA:3.40.50.720 1 292 1.1E-73 T 12-10-2018 VAPA_1c13780 4c06209c399d868e89358fa9842cbc3c 301 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 11 246 1.2E-40 T 12-10-2018 VAPA_1c13780 4c06209c399d868e89358fa9842cbc3c 301 SUPERFAMILY SSF51735 3 252 2.01E-64 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c13780 4c06209c399d868e89358fa9842cbc3c 301 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 149 177 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 VAPA_1c13780 4c06209c399d868e89358fa9842cbc3c 301 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 89 100 4.5E-24 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c13780 4c06209c399d868e89358fa9842cbc3c 301 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 4.5E-24 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c13780 4c06209c399d868e89358fa9842cbc3c 301 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 136 152 4.5E-24 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c13780 4c06209c399d868e89358fa9842cbc3c 301 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 214 234 4.5E-24 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c13780 4c06209c399d868e89358fa9842cbc3c 301 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 162 181 4.5E-24 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c06500 4eb0a7b286f24089b10ad5e9d7db8eb5 511 Gene3D G3DSA:3.40.50.300 100 290 1.5E-5 T 12-10-2018 VAPA_1c06500 4eb0a7b286f24089b10ad5e9d7db8eb5 511 SUPERFAMILY SSF52540 126 299 2.56E-7 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c06500 4eb0a7b286f24089b10ad5e9d7db8eb5 511 Pfam PF13401 AAA domain 125 268 2.8E-8 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c01080 0685a85688389bf27ff22e3f84757edb 265 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 89 259 5.9E-20 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 VAPA_1c01080 0685a85688389bf27ff22e3f84757edb 265 SUPERFAMILY SSF161098 66 247 5.36E-24 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c01080 0685a85688389bf27ff22e3f84757edb 265 Gene3D G3DSA:1.10.3720.10 68 261 2.5E-17 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c29160 5768ebde51c1b8a224b29aaa965ef20b 227 SUPERFAMILY SSF46785 6 72 4.72E-19 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c29160 5768ebde51c1b8a224b29aaa965ef20b 227 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 137 147 2.0E-11 T 12-10-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 VAPA_1c29160 5768ebde51c1b8a224b29aaa965ef20b 227 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 176 188 2.0E-11 T 12-10-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 VAPA_1c29160 5768ebde51c1b8a224b29aaa965ef20b 227 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 148 159 2.0E-11 T 12-10-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 VAPA_1c29160 5768ebde51c1b8a224b29aaa965ef20b 227 SUPERFAMILY SSF51306 101 223 1.92E-35 T 12-10-2018 IPR036286 LexA/Signal peptidase-like superfamily VAPA_1c29160 5768ebde51c1b8a224b29aaa965ef20b 227 Gene3D G3DSA:1.10.10.10 5 72 1.3E-26 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c29160 5768ebde51c1b8a224b29aaa965ef20b 227 Gene3D G3DSA:2.10.109.10 106 227 2.4E-40 T 12-10-2018 VAPA_1c29160 5768ebde51c1b8a224b29aaa965ef20b 227 Hamap MF_00015 LexA repressor [lexA]. 6 224 30.94 T 12-10-2018 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 VAPA_1c29160 5768ebde51c1b8a224b29aaa965ef20b 227 Pfam PF01726 LexA DNA binding domain 6 68 4.8E-26 T 12-10-2018 IPR006199 LexA repressor, DNA-binding domain GO:0004252|GO:0006508 VAPA_1c29160 5768ebde51c1b8a224b29aaa965ef20b 227 TIGRFAM TIGR00498 lexA: repressor LexA 6 224 1.3E-68 T 12-10-2018 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 VAPA_1c29160 5768ebde51c1b8a224b29aaa965ef20b 227 Pfam PF00717 Peptidase S24-like 140 206 9.7E-15 T 12-10-2018 IPR015927 Peptidase S24/S26A/S26B/S26C VAPA_1c50390 4f4b181e1cccc6576d1f9db6768a824d 170 Gene3D G3DSA:3.10.180.10 1 151 3.4E-18 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase VAPA_1c50390 4f4b181e1cccc6576d1f9db6768a824d 170 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 11 132 2.5E-4 T 12-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain VAPA_1c50390 4f4b181e1cccc6576d1f9db6768a824d 170 SUPERFAMILY SSF54593 10 137 7.29E-20 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase VAPA_1c01710 5d150bbd59d1e149c03c4510ec637cea 398 Pfam PF13458 Periplasmic binding protein 31 372 1.7E-66 T 12-10-2018 IPR028081 Leucine-binding protein domain VAPA_1c01710 5d150bbd59d1e149c03c4510ec637cea 398 Gene3D G3DSA:3.40.50.2300 33 364 1.4E-112 T 12-10-2018 VAPA_1c01710 5d150bbd59d1e149c03c4510ec637cea 398 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 94 104 6.8E-5 T 12-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 VAPA_1c01710 5d150bbd59d1e149c03c4510ec637cea 398 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 32 48 6.8E-5 T 12-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 VAPA_1c01710 5d150bbd59d1e149c03c4510ec637cea 398 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 286 299 6.8E-5 T 12-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 VAPA_1c01710 5d150bbd59d1e149c03c4510ec637cea 398 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 341 356 6.8E-5 T 12-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 VAPA_1c01710 5d150bbd59d1e149c03c4510ec637cea 398 SUPERFAMILY SSF53822 31 388 1.02E-82 T 12-10-2018 IPR028082 Periplasmic binding protein-like I VAPA_1c01710 5d150bbd59d1e149c03c4510ec637cea 398 Gene3D G3DSA:3.40.50.2300 148 376 1.4E-112 T 12-10-2018 VAPA_1c13020 79488a1a9544975df258c2709a8b475b 438 SUPERFAMILY SSF56801 30 432 8.5E-65 T 12-10-2018 VAPA_1c13020 79488a1a9544975df258c2709a8b475b 438 Gene3D G3DSA:3.30.300.30 331 437 7.9E-29 T 12-10-2018 VAPA_1c13020 79488a1a9544975df258c2709a8b475b 438 TIGRFAM TIGR02155 PA_CoA_ligase: phenylacetate-CoA ligase 15 436 4.0E-214 T 12-10-2018 IPR011880 Phenylacetate-CoA ligase GO:0010124|GO:0047475 KEGG: 00360+6.2.1.30|MetaCyc: PWY-1341|MetaCyc: PWY-6318|MetaCyc: PWY-7716 VAPA_1c13020 79488a1a9544975df258c2709a8b475b 438 Pfam PF00501 AMP-binding enzyme 88 293 4.6E-17 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 VAPA_1c13020 79488a1a9544975df258c2709a8b475b 438 Pfam PF14535 AMP-binding enzyme C-terminal domain 339 436 1.4E-21 T 12-10-2018 IPR028154 AMP-dependent ligase, C-terminal VAPA_1c13020 79488a1a9544975df258c2709a8b475b 438 PIRSF PIRSF006444 5 438 2.0E-202 T 12-10-2018 IPR011880 Phenylacetate-CoA ligase GO:0010124|GO:0047475 KEGG: 00360+6.2.1.30|MetaCyc: PWY-1341|MetaCyc: PWY-6318|MetaCyc: PWY-7716 VAPA_1c13020 79488a1a9544975df258c2709a8b475b 438 Gene3D G3DSA:3.40.50.12780 2 330 5.5E-137 T 12-10-2018 VAPA_1c49370 41a38bb65e91c1cb48ac594acf8c4933 635 Gene3D G3DSA:1.10.287.380 553 635 3.0E-15 T 12-10-2018 IPR037118 Valyl-tRNA synthetase, tRNA-binding arm superfamily GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: R-HSA-379716 VAPA_1c49370 41a38bb65e91c1cb48ac594acf8c4933 635 Pfam PF00005 ABC transporter 19 175 2.1E-24 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c49370 41a38bb65e91c1cb48ac594acf8c4933 635 SUPERFAMILY SSF52540 304 509 4.09E-46 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c49370 41a38bb65e91c1cb48ac594acf8c4933 635 Pfam PF12848 ABC transporter 214 284 1.1E-12 T 12-10-2018 IPR032781 ABC-transporter extension domain VAPA_1c49370 41a38bb65e91c1cb48ac594acf8c4933 635 SMART SM00382 334 505 7.4E-14 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c49370 41a38bb65e91c1cb48ac594acf8c4933 635 SMART SM00382 28 220 4.6E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c49370 41a38bb65e91c1cb48ac594acf8c4933 635 Gene3D G3DSA:3.40.50.300 9 269 5.8E-63 T 12-10-2018 VAPA_1c49370 41a38bb65e91c1cb48ac594acf8c4933 635 SUPERFAMILY SSF52540 4 222 3.61E-46 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c49370 41a38bb65e91c1cb48ac594acf8c4933 635 Gene3D G3DSA:3.40.50.300 271 535 1.5E-63 T 12-10-2018 VAPA_1c49370 41a38bb65e91c1cb48ac594acf8c4933 635 ProSitePatterns PS00211 ABC transporters family signature. 431 445 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_1c49370 41a38bb65e91c1cb48ac594acf8c4933 635 Pfam PF00005 ABC transporter 329 459 8.4E-23 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c49370 41a38bb65e91c1cb48ac594acf8c4933 635 Pfam PF16326 ABC transporter C-terminal domain 562 632 4.8E-15 T 12-10-2018 IPR032524 ABC transporter Uup, C-terminal GO:0003677 VAPA_2c07530 e8adad2b0ec4df10666e6b90501782a2 258 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 155 196 - T 12-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 VAPA_2c07530 e8adad2b0ec4df10666e6b90501782a2 258 SUPERFAMILY SSF46689 151 200 2.24E-7 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 VAPA_2c07530 e8adad2b0ec4df10666e6b90501782a2 258 SUPERFAMILY SSF46689 203 249 5.82E-7 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 VAPA_2c07530 e8adad2b0ec4df10666e6b90501782a2 258 SMART SM00342 167 249 1.1E-23 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 VAPA_2c07530 e8adad2b0ec4df10666e6b90501782a2 258 Gene3D G3DSA:1.10.10.60 151 254 3.6E-20 T 12-10-2018 VAPA_2c07530 e8adad2b0ec4df10666e6b90501782a2 258 Pfam PF12852 Cupin 66 135 3.3E-10 T 12-10-2018 IPR032783 AraC-type transcription regulator, ligand-binding domain VAPA_2c07530 e8adad2b0ec4df10666e6b90501782a2 258 Pfam PF12833 Helix-turn-helix domain 173 247 2.9E-17 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 VAPA_1c04450 8f95c891f587e6a99dcd56c15a002d76 79 Gene3D G3DSA:1.20.20.10 2 75 1.3E-24 T 12-10-2018 IPR038662 F1F0 ATP synthase subunit C superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 VAPA_1c04450 8f95c891f587e6a99dcd56c15a002d76 79 SUPERFAMILY SSF81333 5 76 1.19E-14 T 12-10-2018 IPR035921 F/V-ATP synthase subunit C superfamily VAPA_1c04450 8f95c891f587e6a99dcd56c15a002d76 79 TIGRFAM TIGR01260 ATP_synt_c: ATP synthase F0, C subunit 18 73 8.6E-20 T 12-10-2018 IPR005953 ATP synthase, F0 complex, subunit C, bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 VAPA_1c04450 8f95c891f587e6a99dcd56c15a002d76 79 Pfam PF00137 ATP synthase subunit C 9 69 2.1E-9 T 12-10-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 VAPA_1c04450 8f95c891f587e6a99dcd56c15a002d76 79 ProSitePatterns PS00605 ATP synthase c subunit signature. 38 59 - T 12-10-2018 IPR020537 ATP synthase, F0 complex, subunit C, DCCD-binding site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 VAPA_2c08190 15d4d97ee827bff81cd9ef1aad6b1d95 80 Pfam PF13333 Integrase core domain 38 74 5.3E-10 T 12-10-2018 IPR001584 Integrase, catalytic core GO:0015074 VAPA_2c08190 15d4d97ee827bff81cd9ef1aad6b1d95 80 SUPERFAMILY SSF53098 35 77 7.33E-5 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily VAPA_1c40470 e4c0da306991889d0f73751666026673 401 Pfam PF06181 Urate oxidase N-terminal 4 306 8.9E-133 T 12-10-2018 IPR010389 Urate oxidase N-terminal VAPA_1c40470 e4c0da306991889d0f73751666026673 401 SUPERFAMILY SSF46626 301 399 3.39E-7 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 VAPA_1c46400 8bea3da01304d110f8d44e195e1b813e 241 SUPERFAMILY SSF49482 12 240 1.7E-69 T 12-10-2018 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 VAPA_1c46400 8bea3da01304d110f8d44e195e1b813e 241 TIGRFAM TIGR02422 protocat_beta: protocatechuate 3,4-dioxygenase, beta subunit 20 240 3.6E-103 T 12-10-2018 IPR012785 Protocatechuate 3,4-dioxygenase, beta subunit GO:0005506|GO:0018578|GO:0019619|GO:0055114 KEGG: 00362+1.13.11.3|KEGG: 00624+1.13.11.3|MetaCyc: PWY-6041 VAPA_1c46400 8bea3da01304d110f8d44e195e1b813e 241 Gene3D G3DSA:2.60.130.10 6 241 6.1E-80 T 12-10-2018 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 VAPA_1c46400 8bea3da01304d110f8d44e195e1b813e 241 Pfam PF00775 Dioxygenase 52 232 1.0E-57 T 12-10-2018 IPR000627 Intradiol ring-cleavage dioxygenase, C-terminal GO:0003824|GO:0006725|GO:0008199|GO:0055114 VAPA_1c46400 8bea3da01304d110f8d44e195e1b813e 241 Pfam PF12391 Protocatechuate 3,4-dioxygenase beta subunit N terminal 14 44 2.5E-14 T 12-10-2018 IPR024756 Protocatechuate 3,4-dioxygenase beta subunit, N-terminal KEGG: 00362+1.13.11.3|KEGG: 00624+1.13.11.3|MetaCyc: PWY-6041 VAPA_1c22100 d414343a550c8e23e3819d038d3c107c 278 SUPERFAMILY SSF161098 81 266 5.1E-29 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c22100 d414343a550c8e23e3819d038d3c107c 278 TIGRFAM TIGR01097 PhnE: phosphonate ABC transporter, permease protein PhnE 24 275 6.8E-76 T 12-10-2018 IPR005769 ABC transporter, permease PhnE/PtxC GO:0005887|GO:0015604|GO:0015716 VAPA_1c22100 d414343a550c8e23e3819d038d3c107c 278 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 124 272 8.3E-12 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 VAPA_1c22100 d414343a550c8e23e3819d038d3c107c 278 Gene3D G3DSA:1.10.3720.10 75 276 2.4E-29 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c36460 3ca4b52c8df17d7a16bfc7702f3abb6b 305 SUPERFAMILY SSF161098 28 293 2.75E-43 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c36460 3ca4b52c8df17d7a16bfc7702f3abb6b 305 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 106 292 4.0E-6 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 VAPA_1c36460 3ca4b52c8df17d7a16bfc7702f3abb6b 305 Gene3D G3DSA:1.10.3720.10 21 303 6.0E-39 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c37220 5eb6f0583ff39ff7b5529f71b9897faf 274 Pfam PF02673 Bacitracin resistance protein BacA 9 260 3.9E-87 T 12-10-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 VAPA_1c37220 5eb6f0583ff39ff7b5529f71b9897faf 274 Hamap MF_01006 Undecaprenyl-diphosphatase [uppP]. 4 265 17.926 T 12-10-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 VAPA_1c37220 5eb6f0583ff39ff7b5529f71b9897faf 274 TIGRFAM TIGR00753 undec_PP_bacA: undecaprenyl-diphosphatase UppP 9 258 3.6E-74 T 12-10-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 VAPA_1c01610 bab4cd5bba2e23411da48fee8ef29d07 299 SUPERFAMILY SSF103481 46 145 9.29E-11 T 12-10-2018 VAPA_1c01610 bab4cd5bba2e23411da48fee8ef29d07 299 SUPERFAMILY SSF103481 205 297 2.62E-13 T 12-10-2018 VAPA_1c01610 bab4cd5bba2e23411da48fee8ef29d07 299 Pfam PF00892 EamA-like transporter family 13 143 1.6E-13 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 VAPA_1c01610 bab4cd5bba2e23411da48fee8ef29d07 299 Pfam PF00892 EamA-like transporter family 157 293 7.2E-15 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 VAPA_1c47060 1546f363d520b802f93e232053e379d6 147 Pfam PF04355 SmpA / OmlA family 68 133 2.8E-9 T 12-10-2018 IPR007450 Lipoprotein SmpA/OmlA GO:0019867 VAPA_1c47060 1546f363d520b802f93e232053e379d6 147 Gene3D G3DSA:3.30.1450.10 63 144 1.6E-5 T 12-10-2018 IPR037873 BamE-like VAPA_1c14640 2899623f5e48cb166ea79c5070430a1a 2729 SUPERFAMILY SSF48208 2216 2700 5.67E-84 T 12-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 VAPA_1c14640 2899623f5e48cb166ea79c5070430a1a 2729 Gene3D G3DSA:2.70.98.40 1946 2241 2.2E-60 T 12-10-2018 IPR037018 Glycoside hydrolase family 65, N-terminal domain superfamily VAPA_1c14640 2899623f5e48cb166ea79c5070430a1a 2729 Gene3D G3DSA:2.70.98.40 1455 1744 4.8E-59 T 12-10-2018 IPR037018 Glycoside hydrolase family 65, N-terminal domain superfamily VAPA_1c14640 2899623f5e48cb166ea79c5070430a1a 2729 SUPERFAMILY SSF74650 1458 1711 2.26E-56 T 12-10-2018 IPR011013 Galactose mutarotase-like domain superfamily GO:0003824|GO:0005975|GO:0030246 VAPA_1c14640 2899623f5e48cb166ea79c5070430a1a 2729 Gene3D G3DSA:2.60.420.10 2245 2700 6.8E-171 T 12-10-2018 VAPA_1c14640 2899623f5e48cb166ea79c5070430a1a 2729 Gene3D G3DSA:1.50.10.140 1010 1415 7.7E-19 T 12-10-2018 VAPA_1c14640 2899623f5e48cb166ea79c5070430a1a 2729 Pfam PF10091 Putative glucoamylase 1195 1391 8.1E-9 T 12-10-2018 IPR019282 Domain of unknown function DUF2329 VAPA_1c14640 2899623f5e48cb166ea79c5070430a1a 2729 Gene3D G3DSA:1.50.10.10 2250 2662 6.8E-171 T 12-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 VAPA_1c14640 2899623f5e48cb166ea79c5070430a1a 2729 Pfam PF06165 Glycosyltransferase family 36 1461 1710 6.6E-55 T 12-10-2018 IPR010383 Glycosyl hydrolase 94 VAPA_1c14640 2899623f5e48cb166ea79c5070430a1a 2729 Pfam PF06165 Glycosyltransferase family 36 1966 2206 7.9E-48 T 12-10-2018 IPR010383 Glycosyl hydrolase 94 VAPA_1c14640 2899623f5e48cb166ea79c5070430a1a 2729 SUPERFAMILY SSF74650 1945 2209 3.77E-51 T 12-10-2018 IPR011013 Galactose mutarotase-like domain superfamily GO:0003824|GO:0005975|GO:0030246 VAPA_1c14640 2899623f5e48cb166ea79c5070430a1a 2729 Pfam PF17167 Glycosyl hydrolase 36 superfamily, catalytic domain 2236 2661 2.4E-105 T 12-10-2018 IPR033432 Glycosyl hydrolase 36, catalytic domain VAPA_1c14640 2899623f5e48cb166ea79c5070430a1a 2729 SMART SM01068 1943 2008 5.1E-25 T 12-10-2018 IPR009342 Putative carbohydrate binding domain VAPA_1c14640 2899623f5e48cb166ea79c5070430a1a 2729 SMART SM01068 1435 1496 1.0E-7 T 12-10-2018 IPR009342 Putative carbohydrate binding domain VAPA_1c34510 a0cd7e90343a54c2205c73dd938310ea 155 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 22 149 1.1E-31 T 12-10-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like VAPA_1c34510 a0cd7e90343a54c2205c73dd938310ea 155 Gene3D G3DSA:3.30.530.20 4 153 3.2E-45 T 12-10-2018 IPR023393 START-like domain superfamily VAPA_1c34510 a0cd7e90343a54c2205c73dd938310ea 155 SUPERFAMILY SSF55961 10 152 6.11E-43 T 12-10-2018 VAPA_1c04600 9b234ab4eb9d6429374a5e681347fc43 237 Pfam PF01709 Transcriptional regulator 9 232 7.0E-66 T 12-10-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 VAPA_1c04600 9b234ab4eb9d6429374a5e681347fc43 237 Gene3D G3DSA:3.30.70.980 81 232 8.1E-40 T 12-10-2018 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 VAPA_1c04600 9b234ab4eb9d6429374a5e681347fc43 237 Gene3D G3DSA:1.10.10.200 15 75 3.8E-22 T 12-10-2018 IPR017856 Integrase-like, N-terminal VAPA_1c04600 9b234ab4eb9d6429374a5e681347fc43 237 SUPERFAMILY SSF75625 3 234 2.62E-64 T 12-10-2018 IPR029072 YebC-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 VAPA_1c04600 9b234ab4eb9d6429374a5e681347fc43 237 Gene3D G3DSA:3.30.70.980 128 198 8.1E-40 T 12-10-2018 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 VAPA_1c04600 9b234ab4eb9d6429374a5e681347fc43 237 Hamap MF_00693 Probable transcriptional regulatory protein YebC [yebC]. 1 237 24.007 T 12-10-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 VAPA_1c31350 db21789491eb81cc09b7eca8508c4a8b 366 Gene3D G3DSA:3.30.420.40 7 125 1.1E-16 T 12-10-2018 VAPA_1c31350 db21789491eb81cc09b7eca8508c4a8b 366 Pfam PF01968 Hydantoinase/oxoprolinase 99 337 6.8E-11 T 12-10-2018 IPR002821 Hydantoinase A/oxoprolinase GO:0016787 Reactome: R-HSA-174403|Reactome: R-HSA-5578998 VAPA_1c31350 db21789491eb81cc09b7eca8508c4a8b 366 SUPERFAMILY SSF53067 8 207 7.34E-5 T 12-10-2018 VAPA_1c31350 db21789491eb81cc09b7eca8508c4a8b 366 TIGRFAM TIGR03123 one_C_unchar_1: probable H4MPT-linked C1 transfer pathway protein 9 314 1.7E-88 T 12-10-2018 IPR002756 4-[[4-(2-aminoethyl)phenoxy]-methyl]-2-furanmethanamine-glutamate synthase KEGG: 00680+2.5.1.131|MetaCyc: PWY-5254 VAPA_1c31350 db21789491eb81cc09b7eca8508c4a8b 366 Gene3D G3DSA:3.30.420.190 126 366 1.1E-60 T 12-10-2018 VAPA_1c54330 3a7a6fc5df61105caafba6b45e031e79 401 Pfam PF01546 Peptidase family M20/M25/M40 73 358 9.2E-32 T 12-10-2018 IPR002933 Peptidase M20 GO:0016787 VAPA_1c54330 3a7a6fc5df61105caafba6b45e031e79 401 PIRSF PIRSF005962 2 399 2.6E-120 T 12-10-2018 IPR017439 Amidohydrolase GO:0016787 VAPA_1c54330 3a7a6fc5df61105caafba6b45e031e79 401 Gene3D G3DSA:3.40.630.10 15 381 8.9E-127 T 12-10-2018 VAPA_1c54330 3a7a6fc5df61105caafba6b45e031e79 401 SUPERFAMILY SSF53187 2 397 1.23E-84 T 12-10-2018 VAPA_1c54330 3a7a6fc5df61105caafba6b45e031e79 401 Pfam PF07687 Peptidase dimerisation domain 188 284 6.0E-10 T 12-10-2018 IPR011650 Peptidase M20, dimerisation domain VAPA_1c54330 3a7a6fc5df61105caafba6b45e031e79 401 SUPERFAMILY SSF55031 186 294 7.98E-28 T 12-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain VAPA_1c54330 3a7a6fc5df61105caafba6b45e031e79 401 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 15 385 1.5E-106 T 12-10-2018 IPR017439 Amidohydrolase GO:0016787 VAPA_1c54330 3a7a6fc5df61105caafba6b45e031e79 401 Gene3D G3DSA:3.30.70.360 184 298 8.9E-127 T 12-10-2018 VAPA_1c45380 0272c76edf1f1dd20555488a212c8da2 246 Pfam PF03746 LamB/YcsF family 3 236 7.2E-96 T 12-10-2018 IPR005501 UPF0271 family, LamB/YcsF/PxpA KEGG: 00480+3.5.2.9|MetaCyc: PWY-4041|MetaCyc: PWY-7942 VAPA_1c45380 0272c76edf1f1dd20555488a212c8da2 246 Hamap MF_00691 UPF0271 protein YbgL [ybgL]. 1 240 44.466 T 12-10-2018 IPR005501 UPF0271 family, LamB/YcsF/PxpA KEGG: 00480+3.5.2.9|MetaCyc: PWY-4041|MetaCyc: PWY-7942 VAPA_1c45380 0272c76edf1f1dd20555488a212c8da2 246 SUPERFAMILY SSF88713 1 244 4.89E-95 T 12-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 VAPA_1c45380 0272c76edf1f1dd20555488a212c8da2 246 Gene3D G3DSA:3.20.20.370 1 246 3.0E-104 T 12-10-2018 VAPA_1c54200 14fa760f8b161683dba3f5e9bbf4c20b 90 SUPERFAMILY SSF50249 1 71 1.0E-24 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold VAPA_1c54200 14fa760f8b161683dba3f5e9bbf4c20b 90 Pfam PF01176 Translation initiation factor 1A / IF-1 7 70 1.3E-22 T 12-10-2018 IPR006196 RNA-binding domain, S1, IF1 type GO:0003723|GO:0003743|GO:0006413 VAPA_1c54200 14fa760f8b161683dba3f5e9bbf4c20b 90 TIGRFAM TIGR00008 infA: translation initiation factor IF-1 3 71 3.5E-31 T 12-10-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 VAPA_1c54200 14fa760f8b161683dba3f5e9bbf4c20b 90 Hamap MF_00075 Translation initiation factor IF-1 [infA]. 1 74 25.837 T 12-10-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 VAPA_1c54200 14fa760f8b161683dba3f5e9bbf4c20b 90 Gene3D G3DSA:2.40.50.140 1 71 6.1E-30 T 12-10-2018 VAPA_1c20430 4551d22781b6cb962f584a36b93c6795 263 Pfam PF01614 Bacterial transcriptional regulator 138 230 1.0E-4 T 12-10-2018 IPR014757 Transcription regulator IclR, C-terminal VAPA_1c20430 4551d22781b6cb962f584a36b93c6795 263 SUPERFAMILY SSF46785 16 86 1.6E-11 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c20430 4551d22781b6cb962f584a36b93c6795 263 Gene3D G3DSA:1.10.10.10 2 81 9.3E-18 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c20430 4551d22781b6cb962f584a36b93c6795 263 SMART SM00346 14 104 4.9E-15 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 VAPA_1c20430 4551d22781b6cb962f584a36b93c6795 263 SUPERFAMILY SSF55781 87 255 3.07E-26 T 12-10-2018 VAPA_1c20430 4551d22781b6cb962f584a36b93c6795 263 Pfam PF09339 IclR helix-turn-helix domain 16 66 1.6E-16 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 VAPA_1c20430 4551d22781b6cb962f584a36b93c6795 263 Gene3D G3DSA:3.30.450.40 90 254 3.9E-24 T 12-10-2018 IPR029016 GAF-like domain superfamily VAPA_2c07990 037d8ed04e2ce5542f1fcc4b705cc4ae 224 Pfam PF00486 Transcriptional regulatory protein, C terminal 145 217 2.3E-21 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 VAPA_2c07990 037d8ed04e2ce5542f1fcc4b705cc4ae 224 Gene3D G3DSA:1.10.10.10 123 224 1.5E-26 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_2c07990 037d8ed04e2ce5542f1fcc4b705cc4ae 224 Gene3D G3DSA:3.40.50.2300 1 122 9.9E-41 T 12-10-2018 VAPA_2c07990 037d8ed04e2ce5542f1fcc4b705cc4ae 224 SMART SM00862 144 217 6.1E-23 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 VAPA_2c07990 037d8ed04e2ce5542f1fcc4b705cc4ae 224 SUPERFAMILY SSF46894 117 217 2.1E-24 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 VAPA_2c07990 037d8ed04e2ce5542f1fcc4b705cc4ae 224 Pfam PF00072 Response regulator receiver domain 3 112 8.8E-26 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_2c07990 037d8ed04e2ce5542f1fcc4b705cc4ae 224 SUPERFAMILY SSF52172 1 118 7.97E-38 T 12-10-2018 IPR011006 CheY-like superfamily VAPA_2c07990 037d8ed04e2ce5542f1fcc4b705cc4ae 224 SMART SM00448 1 112 4.5E-38 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_2c01860 ed46bb69c9795b730ab7bfe6dff73161 239 SUPERFAMILY SSF46785 15 81 9.52E-17 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_2c01860 ed46bb69c9795b730ab7bfe6dff73161 239 Pfam PF07729 FCD domain 91 209 5.5E-24 T 12-10-2018 IPR011711 GntR, C-terminal VAPA_2c01860 ed46bb69c9795b730ab7bfe6dff73161 239 Pfam PF00392 Bacterial regulatory proteins, gntR family 18 77 2.7E-17 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_2c01860 ed46bb69c9795b730ab7bfe6dff73161 239 SUPERFAMILY SSF48008 84 216 7.06E-25 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal VAPA_2c01860 ed46bb69c9795b730ab7bfe6dff73161 239 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 51 67 2.9E-5 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_2c01860 ed46bb69c9795b730ab7bfe6dff73161 239 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 37 51 2.9E-5 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_2c01860 ed46bb69c9795b730ab7bfe6dff73161 239 SMART SM00345 19 77 2.3E-14 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_2c01860 ed46bb69c9795b730ab7bfe6dff73161 239 Gene3D G3DSA:1.20.120.530 82 222 6.2E-26 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal VAPA_2c01860 ed46bb69c9795b730ab7bfe6dff73161 239 SMART SM00895 87 211 3.2E-16 T 12-10-2018 IPR011711 GntR, C-terminal VAPA_2c01860 ed46bb69c9795b730ab7bfe6dff73161 239 Gene3D G3DSA:1.10.10.10 15 78 5.2E-20 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c40770 95fd02239c8f2470d99509e5dca13027 208 Pfam PF00440 Bacterial regulatory proteins, tetR family 23 69 1.0E-14 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 VAPA_1c40770 95fd02239c8f2470d99509e5dca13027 208 Gene3D G3DSA:1.10.357.10 5 201 8.0E-35 T 12-10-2018 VAPA_1c40770 95fd02239c8f2470d99509e5dca13027 208 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 23 36 1.3E-9 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 VAPA_1c40770 95fd02239c8f2470d99509e5dca13027 208 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 44 67 1.3E-9 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 VAPA_1c40770 95fd02239c8f2470d99509e5dca13027 208 SUPERFAMILY SSF46689 9 88 3.88E-20 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 VAPA_1c40770 95fd02239c8f2470d99509e5dca13027 208 SUPERFAMILY SSF48498 93 200 1.14E-7 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily VAPA_1c51940 b58e5f49cf490ae3d6341f297e5c6db6 258 SUPERFAMILY SSF46785 169 243 4.3E-14 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c51940 b58e5f49cf490ae3d6341f297e5c6db6 258 Gene3D G3DSA:2.60.120.10 31 161 1.0E-13 T 12-10-2018 IPR014710 RmlC-like jelly roll fold VAPA_1c51940 b58e5f49cf490ae3d6341f297e5c6db6 258 Pfam PF00027 Cyclic nucleotide-binding domain 57 137 6.0E-12 T 12-10-2018 IPR000595 Cyclic nucleotide-binding domain VAPA_1c51940 b58e5f49cf490ae3d6341f297e5c6db6 258 SMART SM00419 187 235 1.8E-5 T 12-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 VAPA_1c51940 b58e5f49cf490ae3d6341f297e5c6db6 258 Pfam PF13545 Crp-like helix-turn-helix domain 171 241 2.0E-13 T 12-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 VAPA_1c51940 b58e5f49cf490ae3d6341f297e5c6db6 258 Gene3D G3DSA:1.10.10.10 170 248 6.4E-15 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c51940 b58e5f49cf490ae3d6341f297e5c6db6 258 SUPERFAMILY SSF51206 28 159 1.83E-22 T 12-10-2018 IPR018490 Cyclic nucleotide-binding-like VAPA_1c35760 d8b1b206e4a4ffb1ac261d8601a0c1b7 329 TIGRFAM TIGR00174 miaA: tRNA dimethylallyltransferase 17 305 1.1E-89 T 12-10-2018 IPR018022 IPP transferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 VAPA_1c35760 d8b1b206e4a4ffb1ac261d8601a0c1b7 329 Gene3D G3DSA:1.10.20.140 123 194 4.5E-94 T 12-10-2018 VAPA_1c35760 d8b1b206e4a4ffb1ac261d8601a0c1b7 329 Gene3D G3DSA:3.40.50.300 20 305 4.5E-94 T 12-10-2018 VAPA_1c35760 d8b1b206e4a4ffb1ac261d8601a0c1b7 329 Hamap MF_00185 tRNA dimethylallyltransferase [miaA]. 16 322 29.938 T 12-10-2018 IPR018022 IPP transferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 VAPA_1c35760 d8b1b206e4a4ffb1ac261d8601a0c1b7 329 SUPERFAMILY SSF52540 18 160 1.32E-18 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c35760 d8b1b206e4a4ffb1ac261d8601a0c1b7 329 Pfam PF01715 IPP transferase 50 304 3.9E-87 T 12-10-2018 IPR018022 IPP transferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 VAPA_1c16980 df5251e6efcb02dfdadde9074b4f8026 567 Pfam PF00361 Proton-conducting membrane transporter 148 374 6.3E-24 T 12-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VAPA_1c39550 ff10c67b95798c5b7182d6da6173ec22 342 SUPERFAMILY SSF46785 3 112 1.36E-20 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c39550 ff10c67b95798c5b7182d6da6173ec22 342 SUPERFAMILY SSF53850 90 291 5.89E-46 T 12-10-2018 VAPA_1c39550 ff10c67b95798c5b7182d6da6173ec22 342 Gene3D G3DSA:3.40.190.290 91 291 5.4E-57 T 12-10-2018 VAPA_1c39550 ff10c67b95798c5b7182d6da6173ec22 342 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 63 1.6E-17 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c39550 ff10c67b95798c5b7182d6da6173ec22 342 Pfam PF03466 LysR substrate binding domain 89 290 1.9E-42 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_1c39550 ff10c67b95798c5b7182d6da6173ec22 342 Gene3D G3DSA:1.10.10.10 3 88 6.0E-22 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c28710 fe988967e5f7645cb96cf54e2d478a88 281 SUPERFAMILY SSF88713 59 279 5.28E-52 T 12-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 VAPA_1c28710 fe988967e5f7645cb96cf54e2d478a88 281 Pfam PF01522 Polysaccharide deacetylase 86 204 1.3E-28 T 12-10-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 VAPA_1c28710 fe988967e5f7645cb96cf54e2d478a88 281 Gene3D G3DSA:3.20.20.370 81 281 2.9E-49 T 12-10-2018 VAPA_2c10740 b3b80bbc4779d5c14dadc493e5f645c8 338 Gene3D G3DSA:3.40.190.150 43 328 2.5E-110 T 12-10-2018 VAPA_2c10740 b3b80bbc4779d5c14dadc493e5f645c8 338 PIRSF PIRSF017082 6 338 3.8E-81 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_2c10740 b3b80bbc4779d5c14dadc493e5f645c8 338 SUPERFAMILY SSF53850 124 287 5.97E-8 T 12-10-2018 VAPA_2c10740 b3b80bbc4779d5c14dadc493e5f645c8 338 Gene3D G3DSA:3.40.190.10 140 263 2.5E-110 T 12-10-2018 VAPA_2c10740 b3b80bbc4779d5c14dadc493e5f645c8 338 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 62 335 1.4E-85 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c50270 9a06b01235f67a7934dd03a906045bb9 257 SUPERFAMILY SSF51735 26 130 3.08E-9 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c50270 9a06b01235f67a7934dd03a906045bb9 257 Gene3D G3DSA:3.40.50.720 23 238 2.2E-6 T 12-10-2018 VAPA_2c00250 0e6c7680a527aa384e8ba776c084f06d 415 SUPERFAMILY SSF53822 34 396 6.39E-90 T 12-10-2018 IPR028082 Periplasmic binding protein-like I VAPA_2c00250 0e6c7680a527aa384e8ba776c084f06d 415 Gene3D G3DSA:3.40.50.2300 37 365 4.0E-130 T 12-10-2018 VAPA_2c00250 0e6c7680a527aa384e8ba776c084f06d 415 Pfam PF13433 Periplasmic binding protein domain 35 397 1.1E-140 T 12-10-2018 VAPA_2c00250 0e6c7680a527aa384e8ba776c084f06d 415 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 57 73 1.7E-5 T 12-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 VAPA_2c00250 0e6c7680a527aa384e8ba776c084f06d 415 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 76 94 1.7E-5 T 12-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 VAPA_2c00250 0e6c7680a527aa384e8ba776c084f06d 415 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 287 300 1.7E-5 T 12-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 VAPA_2c00250 0e6c7680a527aa384e8ba776c084f06d 415 Gene3D G3DSA:3.40.50.2300 150 382 4.0E-130 T 12-10-2018 VAPA_2c02030 8f9ad03dfbea86db63f720785ac1f353 471 ProSitePatterns PS00080 Multicopper oxidases signature 2. 320 331 - T 12-10-2018 IPR002355 Multicopper oxidase, copper-binding site GO:0005507 VAPA_2c02030 8f9ad03dfbea86db63f720785ac1f353 471 Gene3D G3DSA:2.60.40.420 74 196 5.3E-76 T 12-10-2018 IPR008972 Cupredoxin VAPA_2c02030 8f9ad03dfbea86db63f720785ac1f353 471 Pfam PF07732 Multicopper oxidase 89 195 3.6E-36 T 12-10-2018 IPR011707 Multicopper oxidase, type 3 GO:0005507 VAPA_2c02030 8f9ad03dfbea86db63f720785ac1f353 471 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 2 29 0.001 T 12-10-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal VAPA_2c02030 8f9ad03dfbea86db63f720785ac1f353 471 Gene3D G3DSA:2.60.40.420 197 332 5.3E-76 T 12-10-2018 IPR008972 Cupredoxin VAPA_2c02030 8f9ad03dfbea86db63f720785ac1f353 471 SUPERFAMILY SSF49503 174 331 1.57E-31 T 12-10-2018 IPR008972 Cupredoxin VAPA_2c02030 8f9ad03dfbea86db63f720785ac1f353 471 SUPERFAMILY SSF49503 69 219 2.62E-39 T 12-10-2018 IPR008972 Cupredoxin VAPA_2c02030 8f9ad03dfbea86db63f720785ac1f353 471 Pfam PF07731 Multicopper oxidase 221 335 2.7E-23 T 12-10-2018 IPR011706 Multicopper oxidase, type 2 GO:0005507|GO:0016491|GO:0055114 VAPA_1c44850 8a354c5a1dc13129ce580c7a3ae49e24 238 SUPERFAMILY SSF109604 2 207 4.94E-19 T 12-10-2018 VAPA_1c44850 8a354c5a1dc13129ce580c7a3ae49e24 238 Gene3D G3DSA:1.10.3210.10 1 233 5.8E-44 T 12-10-2018 VAPA_1c09350 0f0dfe5a479d719eedf261892529b508 236 Gene3D G3DSA:3.30.2350.10 67 235 8.6E-18 T 12-10-2018 VAPA_1c09350 0f0dfe5a479d719eedf261892529b508 236 SUPERFAMILY SSF55120 69 235 6.0E-14 T 12-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 VAPA_1c09350 0f0dfe5a479d719eedf261892529b508 236 SMART SM00363 9 72 3.2E-6 T 12-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VAPA_1c09350 0f0dfe5a479d719eedf261892529b508 236 Pfam PF01479 S4 domain 10 51 2.9E-7 T 12-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VAPA_1c09350 0f0dfe5a479d719eedf261892529b508 236 SUPERFAMILY SSF55174 9 82 3.14E-10 T 12-10-2018 VAPA_1c09350 0f0dfe5a479d719eedf261892529b508 236 Gene3D G3DSA:3.10.290.10 4 61 5.4E-12 T 12-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 VAPA_1c02710 6b0d37ec810fea2fb97141e7394bd530 644 SUPERFAMILY SSF56024 415 588 6.63E-7 T 12-10-2018 VAPA_1c02710 6b0d37ec810fea2fb97141e7394bd530 644 Pfam PF13091 PLD-like domain 220 351 4.6E-10 T 12-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 VAPA_1c02710 6b0d37ec810fea2fb97141e7394bd530 644 Gene3D G3DSA:3.30.870.10 204 356 1.8E-17 T 12-10-2018 VAPA_1c02710 6b0d37ec810fea2fb97141e7394bd530 644 Gene3D G3DSA:3.30.870.10 416 591 9.5E-7 T 12-10-2018 VAPA_1c02710 6b0d37ec810fea2fb97141e7394bd530 644 SUPERFAMILY SSF56024 203 358 3.45E-11 T 12-10-2018 VAPA_1c51980 8dff49fb069d0b9d8791e98fabf9a6a1 358 Pfam PF02653 Branched-chain amino acid transport system / permease component 51 331 6.7E-28 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 VAPA_1c29340 e8bfcc8cf292696d5a51a13b1d267695 289 Pfam PF11004 3-deoxy-D-manno-oct-2-ulosonic acid (Kdo) hydroxylase 17 288 8.0E-117 T 12-10-2018 IPR021266 Kdo hydroxylase VAPA_1c04000 0864cbfa5bd3a63809f31401a624105e 364 SUPERFAMILY SSF53187 53 318 9.87E-19 T 12-10-2018 VAPA_1c04000 0864cbfa5bd3a63809f31401a624105e 364 Pfam PF10994 Protein of unknown function (DUF2817) 8 350 5.1E-135 T 12-10-2018 IPR021259 Protein of unknown function DUF2817 VAPA_1c04000 0864cbfa5bd3a63809f31401a624105e 364 Gene3D G3DSA:3.40.630.10 9 245 3.7E-13 T 12-10-2018 VAPA_1c02980 1ce19c4080c6ce39e6e30d0b6bc61b5c 257 SUPERFAMILY SSF56529 49 253 2.75E-70 T 12-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 VAPA_1c02980 1ce19c4080c6ce39e6e30d0b6bc61b5c 257 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 56 253 9.4E-57 T 12-10-2018 IPR011234 Fumarylacetoacetase-like, C-terminal GO:0003824 VAPA_1c02980 1ce19c4080c6ce39e6e30d0b6bc61b5c 257 Gene3D G3DSA:3.90.850.10 46 256 4.9E-73 T 12-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 VAPA_1c02980 1ce19c4080c6ce39e6e30d0b6bc61b5c 257 TIGRFAM TIGR02303 HpaG-C-term: 4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase, C-terminal subunit 2 254 1.7E-112 T 12-10-2018 IPR012684 4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase, C-terminal subunit GO:0008704|GO:0018800|GO:1901023 KEGG: 00350+5.3.3.10+4.1.1.68 VAPA_2c10840 6ade2336bff75743ec62fe7b049863d2 292 SUPERFAMILY SSF53474 34 288 3.18E-39 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_2c10840 6ade2336bff75743ec62fe7b049863d2 292 Gene3D G3DSA:3.40.50.1820 41 287 1.6E-38 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_2c10840 6ade2336bff75743ec62fe7b049863d2 292 Pfam PF12697 Alpha/beta hydrolase family 78 282 7.4E-10 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 VAPA_2c09110 96f8ddde2653d1db8b78c152b10f1e87 193 SMART SM00867 22 187 4.4E-39 T 12-10-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like VAPA_2c09110 96f8ddde2653d1db8b78c152b10f1e87 193 Pfam PF04264 YceI-like domain 23 185 2.1E-31 T 12-10-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like VAPA_2c09110 96f8ddde2653d1db8b78c152b10f1e87 193 Gene3D G3DSA:2.40.128.110 20 187 1.3E-36 T 12-10-2018 IPR036761 Lipid/polyisoprenoid-binding, YceI-like superfamily VAPA_2c09110 96f8ddde2653d1db8b78c152b10f1e87 193 SUPERFAMILY SSF101874 21 186 1.11E-39 T 12-10-2018 IPR036761 Lipid/polyisoprenoid-binding, YceI-like superfamily VAPA_2c01910 3326f2b9b40e2e0e3ff1aed44af1cd33 214 SUPERFAMILY SSF46689 8 92 3.79E-17 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 VAPA_2c01910 3326f2b9b40e2e0e3ff1aed44af1cd33 214 ProSitePatterns PS01081 TetR-type HTH domain signature. 33 64 - T 12-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site VAPA_2c01910 3326f2b9b40e2e0e3ff1aed44af1cd33 214 Pfam PF00440 Bacterial regulatory proteins, tetR family 24 65 5.3E-16 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 VAPA_2c01910 3326f2b9b40e2e0e3ff1aed44af1cd33 214 SUPERFAMILY SSF48498 91 201 2.23E-11 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily VAPA_2c01910 3326f2b9b40e2e0e3ff1aed44af1cd33 214 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 42 65 6.3E-9 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 VAPA_2c01910 3326f2b9b40e2e0e3ff1aed44af1cd33 214 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 21 34 6.3E-9 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 VAPA_2c01910 3326f2b9b40e2e0e3ff1aed44af1cd33 214 Gene3D G3DSA:1.10.357.10 9 211 4.0E-45 T 12-10-2018 VAPA_1c36060 3ac15726c76bba4ed61c5d6b42eec673 491 Pfam PF00361 Proton-conducting membrane transporter 131 414 2.7E-80 T 12-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VAPA_1c36060 3ac15726c76bba4ed61c5d6b42eec673 491 TIGRFAM TIGR01972 NDH_I_M: proton-translocating NADH-quinone oxidoreductase, chain M 4 484 3.8E-186 T 12-10-2018 IPR010227 NADH-quinone oxidoreductase, chain M/4 GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VAPA_1c36060 3ac15726c76bba4ed61c5d6b42eec673 491 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 375 401 7.8E-50 T 12-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VAPA_1c36060 3ac15726c76bba4ed61c5d6b42eec673 491 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 135 154 7.8E-50 T 12-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VAPA_1c36060 3ac15726c76bba4ed61c5d6b42eec673 491 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 165 189 7.8E-50 T 12-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VAPA_1c36060 3ac15726c76bba4ed61c5d6b42eec673 491 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 323 342 7.8E-50 T 12-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VAPA_1c36060 3ac15726c76bba4ed61c5d6b42eec673 491 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 235 259 7.8E-50 T 12-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VAPA_1c09060 754950b39d6383267f47e2bb501ac183 310 Gene3D G3DSA:1.10.10.10 1 88 5.7E-19 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c09060 754950b39d6383267f47e2bb501ac183 310 Gene3D G3DSA:3.40.190.290 90 297 6.3E-50 T 12-10-2018 VAPA_1c09060 754950b39d6383267f47e2bb501ac183 310 Pfam PF03466 LysR substrate binding domain 87 297 1.1E-37 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_1c09060 754950b39d6383267f47e2bb501ac183 310 SUPERFAMILY SSF46785 1 110 3.63E-19 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c09060 754950b39d6383267f47e2bb501ac183 310 SUPERFAMILY SSF53850 87 300 3.08E-42 T 12-10-2018 VAPA_1c09060 754950b39d6383267f47e2bb501ac183 310 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 9.1E-16 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_2c00490 404d9640703eb15edd51358e9de594c4 738 TIGRFAM TIGR01666 YCCS: TIGR01666 family membrane protein 23 662 1.7E-172 T 12-10-2018 IPR010019 Integral membrane protein, YccS VAPA_2c00490 404d9640703eb15edd51358e9de594c4 738 Pfam PF13515 Fusaric acid resistance protein-like 418 536 1.4E-19 T 12-10-2018 VAPA_2c00490 404d9640703eb15edd51358e9de594c4 738 Pfam PF12805 FUSC-like inner membrane protein yccS 72 359 5.4E-88 T 12-10-2018 IPR032692 Integral membrane protein YccS, N-terminal VAPA_2c00490 404d9640703eb15edd51358e9de594c4 738 TIGRFAM TIGR01667 YCCS_YHJK: integral membrane protein, YccS/YhfK family 23 721 1.9E-193 T 12-10-2018 IPR010020 Integral membrane protein, YccS/YhfK VAPA_1c02280 7439097f91c538dcd13f611ae2e81930 189 Pfam PF05591 Type VI secretion system, VipA, VC_A0107 or Hcp2 15 165 2.6E-57 T 12-10-2018 IPR008312 Type VI secretion system, VipA, VC_A0107 or Hcp2 VAPA_1c02280 7439097f91c538dcd13f611ae2e81930 189 PIRSF PIRSF028301 6 181 6.3E-59 T 12-10-2018 IPR008312 Type VI secretion system, VipA, VC_A0107 or Hcp2 VAPA_1c02280 7439097f91c538dcd13f611ae2e81930 189 TIGRFAM TIGR03358 VI_chp_5: type VI secretion protein, VC_A0107 family 11 166 1.1E-55 T 12-10-2018 IPR008312 Type VI secretion system, VipA, VC_A0107 or Hcp2 VAPA_1c24500 a6323623783544db86bd5da089a51dce 506 SUPERFAMILY SSF53067 6 128 9.71E-34 T 12-10-2018 VAPA_1c24500 a6323623783544db86bd5da089a51dce 506 Gene3D G3DSA:1.10.3210.10 311 505 3.6E-43 T 12-10-2018 VAPA_1c24500 a6323623783544db86bd5da089a51dce 506 PIRSF PIRSF001267 1 504 5.0E-161 T 12-10-2018 IPR030673 Pyrophosphatase, GppA/Ppx-type KEGG: 00230+3.6.1.40 VAPA_1c24500 a6323623783544db86bd5da089a51dce 506 SUPERFAMILY SSF109604 313 503 5.02E-35 T 12-10-2018 VAPA_1c24500 a6323623783544db86bd5da089a51dce 506 SUPERFAMILY SSF53067 136 307 1.55E-38 T 12-10-2018 VAPA_1c24500 a6323623783544db86bd5da089a51dce 506 Gene3D G3DSA:3.30.420.40 8 302 2.1E-78 T 12-10-2018 VAPA_1c24500 a6323623783544db86bd5da089a51dce 506 Pfam PF02541 Ppx/GppA phosphatase family 23 307 3.9E-64 T 12-10-2018 IPR003695 Ppx/GppA phosphatase KEGG: 00230+3.6.1.40 VAPA_1c24500 a6323623783544db86bd5da089a51dce 506 Gene3D G3DSA:3.30.420.150 111 294 2.1E-78 T 12-10-2018 VAPA_1c31990 a41aa888ce6a00714799707e7160ad13 307 Gene3D G3DSA:3.40.50.620 5 283 3.5E-83 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold VAPA_1c31990 a41aa888ce6a00714799707e7160ad13 307 Gene3D G3DSA:3.40.50.620 80 239 3.5E-83 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold VAPA_1c31990 a41aa888ce6a00714799707e7160ad13 307 SUPERFAMILY SSF52374 5 266 1.34E-73 T 12-10-2018 VAPA_1c31990 a41aa888ce6a00714799707e7160ad13 307 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 6 261 9.8E-38 T 12-10-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0004812|GO:0005524|GO:0043039 VAPA_1c31990 a41aa888ce6a00714799707e7160ad13 307 Hamap MF_01428 Glutamyl-Q tRNA(Asp) synthetase [gluQ]. 3 301 39.303 T 12-10-2018 IPR022380 Glutamyl-Q tRNA(Asp) synthetase GO:0000166|GO:0004812|GO:0006400 VAPA_1c31990 a41aa888ce6a00714799707e7160ad13 307 PRINTS PR00987 Glutamyl-tRNA synthetase signature 6 18 4.7E-7 T 12-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 VAPA_1c31990 a41aa888ce6a00714799707e7160ad13 307 PRINTS PR00987 Glutamyl-tRNA synthetase signature 191 201 4.7E-7 T 12-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 VAPA_1c31990 a41aa888ce6a00714799707e7160ad13 307 PRINTS PR00987 Glutamyl-tRNA synthetase signature 207 215 4.7E-7 T 12-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 VAPA_1c31990 a41aa888ce6a00714799707e7160ad13 307 TIGRFAM TIGR03838 queuosine_YadB: glutamyl-queuosine tRNA(Asp) synthetase 4 285 2.3E-107 T 12-10-2018 IPR022380 Glutamyl-Q tRNA(Asp) synthetase GO:0000166|GO:0004812|GO:0006400 VAPA_1c22010 787dac0a2c9b258f3c73c691108bd169 336 Gene3D G3DSA:3.40.50.2300 63 308 6.0E-76 T 12-10-2018 VAPA_1c22010 787dac0a2c9b258f3c73c691108bd169 336 Gene3D G3DSA:1.10.260.40 1 59 2.1E-16 T 12-10-2018 VAPA_1c22010 787dac0a2c9b258f3c73c691108bd169 336 SMART SM00354 1 72 1.6E-14 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 VAPA_1c22010 787dac0a2c9b258f3c73c691108bd169 336 Pfam PF13377 Periplasmic binding protein-like domain 169 336 1.2E-34 T 12-10-2018 VAPA_1c22010 787dac0a2c9b258f3c73c691108bd169 336 Pfam PF00356 Bacterial regulatory proteins, lacI family 1 48 5.6E-13 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 VAPA_1c22010 787dac0a2c9b258f3c73c691108bd169 336 SUPERFAMILY SSF53822 59 317 8.7E-61 T 12-10-2018 IPR028082 Periplasmic binding protein-like I VAPA_1c22010 787dac0a2c9b258f3c73c691108bd169 336 SUPERFAMILY SSF47413 1 60 7.5E-12 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 VAPA_1c22010 787dac0a2c9b258f3c73c691108bd169 336 Gene3D G3DSA:3.40.50.2300 160 292 6.0E-76 T 12-10-2018 VAPA_1c00780 20abd826d96769aaf8a9b4d0dfb71c63 605 Pfam PF00501 AMP-binding enzyme 47 455 4.0E-53 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 VAPA_1c00780 20abd826d96769aaf8a9b4d0dfb71c63 605 ProSitePatterns PS00455 Putative AMP-binding domain signature. 216 227 - T 12-10-2018 IPR020845 AMP-binding, conserved site VAPA_1c00780 20abd826d96769aaf8a9b4d0dfb71c63 605 Gene3D G3DSA:3.40.50.12780 28 457 4.2E-65 T 12-10-2018 VAPA_1c00780 20abd826d96769aaf8a9b4d0dfb71c63 605 SUPERFAMILY SSF56801 28 580 1.7E-80 T 12-10-2018 VAPA_2c12470 1538bdeea64b3c8a4010eaf81aded206 214 Pfam PF04299 Putative FMN-binding domain 2 168 1.8E-55 T 12-10-2018 IPR007396 Transcriptional regulator PAI 2-type VAPA_2c12470 1538bdeea64b3c8a4010eaf81aded206 214 Gene3D G3DSA:2.30.110.10 1 211 5.0E-63 T 12-10-2018 IPR012349 FMN-binding split barrel GO:0048037 VAPA_2c12470 1538bdeea64b3c8a4010eaf81aded206 214 SUPERFAMILY SSF50475 11 196 2.75E-30 T 12-10-2018 VAPA_2c12470 1538bdeea64b3c8a4010eaf81aded206 214 PIRSF PIRSF010372 1 212 2.9E-62 T 12-10-2018 IPR007396 Transcriptional regulator PAI 2-type VAPA_1c31950 afadad90ac38d86f6d669c03cdcf267f 233 Pfam PF02678 Pirin 5 119 4.5E-36 T 12-10-2018 IPR003829 Pirin, N-terminal domain Reactome: R-HSA-8935690 VAPA_1c31950 afadad90ac38d86f6d669c03cdcf267f 233 Gene3D G3DSA:2.60.120.10 8 231 2.7E-92 T 12-10-2018 IPR014710 RmlC-like jelly roll fold VAPA_1c31950 afadad90ac38d86f6d669c03cdcf267f 233 Gene3D G3DSA:2.60.120.10 11 135 2.7E-92 T 12-10-2018 IPR014710 RmlC-like jelly roll fold VAPA_1c31950 afadad90ac38d86f6d669c03cdcf267f 233 SUPERFAMILY SSF51182 1 231 2.57E-78 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily VAPA_1c31950 afadad90ac38d86f6d669c03cdcf267f 233 PIRSF PIRSF006232 1 232 1.7E-56 T 12-10-2018 IPR012093 Pirin Reactome: R-HSA-8935690 VAPA_1c48040 7e397484709de4dd705efeba9f4282b5 449 SUPERFAMILY SSF52799 288 434 2.12E-15 T 12-10-2018 IPR029021 Protein-tyrosine phosphatase-like VAPA_1c48040 7e397484709de4dd705efeba9f4282b5 449 Pfam PF14378 PAP2 superfamily 54 198 1.7E-6 T 12-10-2018 IPR026841 Inositolphosphotransferase Aur1/Ipt1 VAPA_1c48040 7e397484709de4dd705efeba9f4282b5 449 Pfam PF00782 Dual specificity phosphatase, catalytic domain 357 430 4.6E-6 T 12-10-2018 IPR000340 Dual specificity phosphatase, catalytic domain GO:0008138|GO:0016311 VAPA_1c48040 7e397484709de4dd705efeba9f4282b5 449 Gene3D G3DSA:3.90.190.10 296 436 1.5E-13 T 12-10-2018 IPR029021 Protein-tyrosine phosphatase-like VAPA_1c24670 6f502c5def7de3e37d9f28fd483def8b 229 SUPERFAMILY SSF46785 4 107 3.93E-26 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c24670 6f502c5def7de3e37d9f28fd483def8b 229 Gene3D G3DSA:3.30.1050.10 132 216 2.9E-6 T 12-10-2018 IPR036527 SCP2 sterol-binding domain superfamily VAPA_1c24670 6f502c5def7de3e37d9f28fd483def8b 229 Pfam PF01638 HxlR-like helix-turn-helix 16 101 2.7E-22 T 12-10-2018 IPR002577 Helix-turn-helix, HxlR type VAPA_1c24670 6f502c5def7de3e37d9f28fd483def8b 229 Gene3D G3DSA:1.10.10.10 4 112 5.8E-30 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c24670 6f502c5def7de3e37d9f28fd483def8b 229 SUPERFAMILY SSF55718 132 216 3.87E-10 T 12-10-2018 IPR036527 SCP2 sterol-binding domain superfamily VAPA_1c40180 051865ce07ea695363189e3987a48da2 289 Gene3D G3DSA:3.20.20.60 1 287 1.7E-84 T 12-10-2018 VAPA_1c40180 051865ce07ea695363189e3987a48da2 289 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 2 221 3.1E-42 T 12-10-2018 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 VAPA_1c40180 051865ce07ea695363189e3987a48da2 289 SUPERFAMILY SSF51621 1 231 4.89E-58 T 12-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 VAPA_1c40180 051865ce07ea695363189e3987a48da2 289 PIRSF PIRSF015582 1 288 3.3E-73 T 12-10-2018 IPR011206 Citrate lyase beta subunit-like VAPA_2c09640 35f0a7cc8b34b5e640f3a0c40e34d399 253 SUPERFAMILY SSF55781 76 250 1.5E-45 T 12-10-2018 VAPA_2c09640 35f0a7cc8b34b5e640f3a0c40e34d399 253 SUPERFAMILY SSF46785 7 75 6.24E-9 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_2c09640 35f0a7cc8b34b5e640f3a0c40e34d399 253 Gene3D G3DSA:1.10.10.10 1 65 7.8E-16 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_2c09640 35f0a7cc8b34b5e640f3a0c40e34d399 253 Pfam PF09339 IclR helix-turn-helix domain 9 60 2.2E-11 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 VAPA_2c09640 35f0a7cc8b34b5e640f3a0c40e34d399 253 SMART SM00346 7 95 4.4E-18 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 VAPA_2c09640 35f0a7cc8b34b5e640f3a0c40e34d399 253 Pfam PF01614 Bacterial transcriptional regulator 124 245 7.4E-32 T 12-10-2018 IPR014757 Transcription regulator IclR, C-terminal VAPA_2c09640 35f0a7cc8b34b5e640f3a0c40e34d399 253 Gene3D G3DSA:3.30.450.40 74 252 6.6E-53 T 12-10-2018 IPR029016 GAF-like domain superfamily VAPA_1c19930 7e301ea3d92a062a29de12fd645b5ec5 143 TIGRFAM TIGR00014 arsC: arsenate reductase (glutaredoxin) 4 116 4.0E-44 T 12-10-2018 IPR006659 Arsenate reductase GO:0008794|GO:0055114 MetaCyc: PWY-4202|MetaCyc: PWY-4621 VAPA_1c19930 7e301ea3d92a062a29de12fd645b5ec5 143 SUPERFAMILY SSF52833 3 138 7.13E-42 T 12-10-2018 IPR036249 Thioredoxin-like superfamily VAPA_1c19930 7e301ea3d92a062a29de12fd645b5ec5 143 Gene3D G3DSA:3.40.30.10 1 141 4.0E-61 T 12-10-2018 VAPA_1c19930 7e301ea3d92a062a29de12fd645b5ec5 143 Pfam PF03960 ArsC family 7 115 1.5E-19 T 12-10-2018 IPR006660 Arsenate reductase-like VAPA_1c19470 3725836207db0b16467121d46a1d4d32 171 Gene3D G3DSA:3.40.50.960 13 168 2.3E-47 T 12-10-2018 IPR036467 Lumazine/riboflavin synthase superfamily GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 VAPA_1c19470 3725836207db0b16467121d46a1d4d32 171 Pfam PF00885 6,7-dimethyl-8-ribityllumazine synthase 22 159 1.1E-35 T 12-10-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 VAPA_1c19470 3725836207db0b16467121d46a1d4d32 171 SUPERFAMILY SSF52121 19 164 2.35E-44 T 12-10-2018 IPR036467 Lumazine/riboflavin synthase superfamily GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 VAPA_1c19470 3725836207db0b16467121d46a1d4d32 171 Hamap MF_00178 6,7-dimethyl-8-ribityllumazine synthase [ribH]. 16 164 22.389 T 12-10-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 VAPA_2c07230 ace67ee02b27c2ddbebf79938305e3ed 487 Gene3D G3DSA:2.20.200.10 108 371 1.3E-135 T 12-10-2018 VAPA_2c07230 ace67ee02b27c2ddbebf79938305e3ed 487 Pfam PF02321 Outer membrane efflux protein 72 270 7.2E-29 T 12-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 VAPA_2c07230 ace67ee02b27c2ddbebf79938305e3ed 487 Pfam PF02321 Outer membrane efflux protein 298 480 1.6E-26 T 12-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 VAPA_2c07230 ace67ee02b27c2ddbebf79938305e3ed 487 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 11 481 1.0E-123 T 12-10-2018 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0016020|GO:0022857|GO:0055085 VAPA_2c07230 ace67ee02b27c2ddbebf79938305e3ed 487 Gene3D G3DSA:1.20.1600.10 62 480 1.3E-135 T 12-10-2018 VAPA_2c07230 ace67ee02b27c2ddbebf79938305e3ed 487 SUPERFAMILY SSF56954 2 483 3.79E-106 T 12-10-2018 VAPA_1c26850 2ee83cedb77f72d37a25ba2be306eecb 128 Pfam PF13665 Domain of unknown function (DUF4150) 9 113 5.1E-38 T 12-10-2018 IPR025425 Domain of unknown function DUF4150 VAPA_1c43070 9819f0ce0f2f6845cf12510331dae699 132 Pfam PF00072 Response regulator receiver domain 8 120 1.3E-30 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_1c43070 9819f0ce0f2f6845cf12510331dae699 132 SMART SM00448 6 120 5.2E-35 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_1c43070 9819f0ce0f2f6845cf12510331dae699 132 SUPERFAMILY SSF52172 5 128 1.85E-35 T 12-10-2018 IPR011006 CheY-like superfamily VAPA_1c43070 9819f0ce0f2f6845cf12510331dae699 132 Gene3D G3DSA:3.40.50.12740 5 132 9.8E-38 T 12-10-2018 VAPA_1c34730 4e96348f03f62eba123ae482567017e3 323 Pfam PF01882 Protein of unknown function DUF58 216 296 5.6E-10 T 12-10-2018 IPR002881 Domain of unknown function DUF58 VAPA_1c39350 9e86c5697b319415426213c0a0d5e4e8 330 SUPERFAMILY SSF53850 119 292 6.52E-13 T 12-10-2018 VAPA_1c39350 9e86c5697b319415426213c0a0d5e4e8 330 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 56 325 2.4E-71 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c39350 9e86c5697b319415426213c0a0d5e4e8 330 Gene3D G3DSA:3.40.190.150 37 320 2.2E-102 T 12-10-2018 VAPA_1c39350 9e86c5697b319415426213c0a0d5e4e8 330 Gene3D G3DSA:3.40.190.10 134 255 2.2E-102 T 12-10-2018 VAPA_1c39350 9e86c5697b319415426213c0a0d5e4e8 330 PIRSF PIRSF017082 1 329 1.0E-73 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_2c03940 72cea1222b9bad9616558fbbc6380fb7 149 Pfam PF10116 Protein required for attachment to host cells 5 140 1.7E-35 T 12-10-2018 IPR019291 Host attachment protein VAPA_2c06740 6126c3f3f3141e5a59c2a8645b684e60 167 Gene3D G3DSA:1.20.120.530 25 162 5.5E-28 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal VAPA_2c06740 6126c3f3f3141e5a59c2a8645b684e60 167 Pfam PF07729 FCD domain 26 150 2.2E-26 T 12-10-2018 IPR011711 GntR, C-terminal VAPA_2c06740 6126c3f3f3141e5a59c2a8645b684e60 167 SMART SM00895 26 152 3.7E-21 T 12-10-2018 IPR011711 GntR, C-terminal VAPA_2c06740 6126c3f3f3141e5a59c2a8645b684e60 167 SUPERFAMILY SSF48008 23 156 3.4E-26 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal VAPA_1c42720 c7d6b7272ec0d2cc8672ed808ed861e3 293 Pfam PF00892 EamA-like transporter family 156 290 6.1E-10 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 VAPA_1c42720 c7d6b7272ec0d2cc8672ed808ed861e3 293 Pfam PF00892 EamA-like transporter family 6 135 2.4E-9 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 VAPA_1c42720 c7d6b7272ec0d2cc8672ed808ed861e3 293 SUPERFAMILY SSF103481 199 292 2.48E-10 T 12-10-2018 VAPA_1c42720 c7d6b7272ec0d2cc8672ed808ed861e3 293 Gene3D G3DSA:1.10.3730.20 57 138 3.5E-5 T 12-10-2018 VAPA_1c42720 c7d6b7272ec0d2cc8672ed808ed861e3 293 SUPERFAMILY SSF103481 42 139 6.93E-13 T 12-10-2018 VAPA_1c36260 23e5a17fe30e75dc304f39d6809b0e35 426 SUPERFAMILY SSF53822 34 388 5.72E-64 T 12-10-2018 IPR028082 Periplasmic binding protein-like I VAPA_1c36260 23e5a17fe30e75dc304f39d6809b0e35 426 Pfam PF13458 Periplasmic binding protein 34 388 8.1E-63 T 12-10-2018 IPR028081 Leucine-binding protein domain VAPA_1c36260 23e5a17fe30e75dc304f39d6809b0e35 426 Gene3D G3DSA:3.40.50.2300 165 421 1.9E-136 T 12-10-2018 VAPA_1c36260 23e5a17fe30e75dc304f39d6809b0e35 426 Gene3D G3DSA:3.40.50.2300 34 378 1.9E-136 T 12-10-2018 VAPA_1c19640 47a214ca37a153dd52174ec9fc32a87a 439 PIRSF PIRSF001362 6 439 5.8E-228 T 12-10-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 VAPA_1c19640 47a214ca37a153dd52174ec9fc32a87a 439 Pfam PF00463 Isocitrate lyase family 20 260 3.9E-59 T 12-10-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 VAPA_1c19640 47a214ca37a153dd52174ec9fc32a87a 439 Pfam PF00463 Isocitrate lyase family 261 438 4.6E-51 T 12-10-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 VAPA_1c19640 47a214ca37a153dd52174ec9fc32a87a 439 ProSitePatterns PS00161 Isocitrate lyase signature. 198 203 - T 12-10-2018 IPR018523 Isocitrate lyase/phosphorylmutase, conserved site GO:0003824 VAPA_1c19640 47a214ca37a153dd52174ec9fc32a87a 439 SUPERFAMILY SSF51621 12 438 1.12E-158 T 12-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 VAPA_1c19640 47a214ca37a153dd52174ec9fc32a87a 439 Gene3D G3DSA:3.20.20.60 7 421 2.1E-179 T 12-10-2018 VAPA_1c19640 47a214ca37a153dd52174ec9fc32a87a 439 TIGRFAM TIGR01346 isocit_lyase: isocitrate lyase 16 260 3.9E-109 T 12-10-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 VAPA_1c19640 47a214ca37a153dd52174ec9fc32a87a 439 TIGRFAM TIGR01346 isocit_lyase: isocitrate lyase 261 438 4.3E-87 T 12-10-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 VAPA_1c42810 7edd042e67a73df70ebf92e5672f780f 521 Pfam PF03109 ABC1 family 109 229 5.5E-31 T 12-10-2018 IPR004147 UbiB domain VAPA_1c42810 7edd042e67a73df70ebf92e5672f780f 521 Hamap MF_00414 Probable protein kinase UbiB [ubiB]. 1 517 49.816 T 12-10-2018 IPR010232 Probable protein kinase UbiB GO:0006744 VAPA_1c42810 7edd042e67a73df70ebf92e5672f780f 521 TIGRFAM TIGR01982 UbiB: 2-polyprenylphenol 6-hydroxylase 5 444 8.5E-167 T 12-10-2018 IPR010232 Probable protein kinase UbiB GO:0006744 VAPA_1c42810 7edd042e67a73df70ebf92e5672f780f 521 SUPERFAMILY SSF56112 90 435 9.42E-37 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily VAPA_1c42800 ff17ff443c0bbeb391a6869806570126 479 Pfam PF00474 Sodium:solute symporter family 30 427 4.2E-42 T 12-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 VAPA_1c42800 ff17ff443c0bbeb391a6869806570126 479 Gene3D G3DSA:1.20.1730.10 4 477 3.5E-74 T 12-10-2018 IPR038377 Sodium/glucose symporter superfamily VAPA_1c17540 7b6fad97f589d1dbd3f14a603856d6d7 214 ProDom PD007559 HYDRATASE NITRILE ALPHA SUBUNIT LYASE CHAIN METAL-BINDING DIRECT SEQUENCING NITRILASE 24 201 7.0E-81 T 12-10-2018 IPR004232 Nitrile hydratase alpha /Thiocyanate hydrolase gamma GO:0003824|GO:0006807|GO:0046914 KEGG: 00364+4.2.1.84|KEGG: 00380+4.2.1.84|KEGG: 00627+4.2.1.84|KEGG: 00643+4.2.1.84|MetaCyc: PWY-5025|MetaCyc: PWY-581|MetaCyc: PWY-7308 VAPA_1c17540 7b6fad97f589d1dbd3f14a603856d6d7 214 PIRSF PIRSF001426 1 210 1.3E-96 T 12-10-2018 IPR023900 Nitrile hydratase alpha subunit /Thiocyanate hydrolase gamma subunit KEGG: 00364+4.2.1.84|KEGG: 00380+4.2.1.84|KEGG: 00627+4.2.1.84|KEGG: 00643+4.2.1.84|MetaCyc: PWY-5025|MetaCyc: PWY-581|MetaCyc: PWY-7308 VAPA_1c17540 7b6fad97f589d1dbd3f14a603856d6d7 214 SUPERFAMILY SSF56209 7 203 2.09E-85 T 12-10-2018 IPR036648 Nitrile hydratase alpha /Thiocyanate hydrolase gamma superfamily GO:0003824|GO:0006807|GO:0046914 KEGG: 00364+4.2.1.84|KEGG: 00380+4.2.1.84|KEGG: 00627+4.2.1.84|KEGG: 00643+4.2.1.84|MetaCyc: PWY-5025|MetaCyc: PWY-581|MetaCyc: PWY-7308 VAPA_1c17540 7b6fad97f589d1dbd3f14a603856d6d7 214 TIGRFAM TIGR01323 nitrile_alph: nitrile hydratase, alpha subunit 21 205 3.2E-93 T 12-10-2018 IPR018141 Nitrile hydratase, alpha subunit GO:0006807|GO:0018822|GO:0046914 KEGG: 00364+4.2.1.84|KEGG: 00380+4.2.1.84|KEGG: 00627+4.2.1.84|KEGG: 00643+4.2.1.84|MetaCyc: PWY-5025|MetaCyc: PWY-581|MetaCyc: PWY-7308 VAPA_1c17540 7b6fad97f589d1dbd3f14a603856d6d7 214 Pfam PF02979 Nitrile hydratase, alpha chain 21 201 3.6E-86 T 12-10-2018 IPR004232 Nitrile hydratase alpha /Thiocyanate hydrolase gamma GO:0003824|GO:0006807|GO:0046914 KEGG: 00364+4.2.1.84|KEGG: 00380+4.2.1.84|KEGG: 00627+4.2.1.84|KEGG: 00643+4.2.1.84|MetaCyc: PWY-5025|MetaCyc: PWY-581|MetaCyc: PWY-7308 VAPA_1c17540 7b6fad97f589d1dbd3f14a603856d6d7 214 Gene3D G3DSA:3.90.330.10 1 210 4.4E-90 T 12-10-2018 IPR036648 Nitrile hydratase alpha /Thiocyanate hydrolase gamma superfamily GO:0003824|GO:0006807|GO:0046914 KEGG: 00364+4.2.1.84|KEGG: 00380+4.2.1.84|KEGG: 00627+4.2.1.84|KEGG: 00643+4.2.1.84|MetaCyc: PWY-5025|MetaCyc: PWY-581|MetaCyc: PWY-7308 VAPA_1c02020 360603ba7852d56dee179202a2eb4e73 271 Gene3D G3DSA:3.40.630.40 3 271 2.9E-73 T 12-10-2018 VAPA_1c02020 360603ba7852d56dee179202a2eb4e73 271 Pfam PF05013 N-formylglutamate amidohydrolase 18 237 1.7E-70 T 12-10-2018 IPR007709 N-formylglutamate amidohydrolase VAPA_1c02020 360603ba7852d56dee179202a2eb4e73 271 TIGRFAM TIGR02017 hutG_amidohyd: N-formylglutamate deformylase 10 269 2.6E-107 T 12-10-2018 IPR010247 N-formylglutamate deformylase VAPA_1c02020 360603ba7852d56dee179202a2eb4e73 271 SUPERFAMILY SSF53187 9 268 8.16E-82 T 12-10-2018 VAPA_1c45240 c483990b6af5afa7ac6d2fda75998a51 497 SUPERFAMILY SSF53850 34 496 5.43E-111 T 12-10-2018 VAPA_1c45240 c483990b6af5afa7ac6d2fda75998a51 497 Gene3D G3DSA:3.90.76.10 40 184 2.7E-102 T 12-10-2018 VAPA_1c45240 c483990b6af5afa7ac6d2fda75998a51 497 Gene3D G3DSA:3.10.105.10 261 470 2.7E-102 T 12-10-2018 VAPA_1c45240 c483990b6af5afa7ac6d2fda75998a51 497 Gene3D G3DSA:3.40.190.10 185 479 2.7E-102 T 12-10-2018 VAPA_1c45240 c483990b6af5afa7ac6d2fda75998a51 497 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 75 401 9.8E-78 T 12-10-2018 IPR000914 Solute-binding protein family 5 domain VAPA_1c45240 c483990b6af5afa7ac6d2fda75998a51 497 PIRSF PIRSF002741 1 497 4.7E-90 T 12-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 VAPA_1c28740 7b1e6544e6bb46a1b445dc0d6e8d1a30 332 PIRSF PIRSF028561 18 332 6.0E-80 T 12-10-2018 IPR014548 Predicted acyltransferase VAPA_1c45130 4499a97174fa660ec85f518ddfca9479 296 Gene3D G3DSA:3.30.70.890 160 293 5.1E-22 T 12-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily VAPA_1c45130 4499a97174fa660ec85f518ddfca9479 296 SUPERFAMILY SSF55060 159 279 3.41E-21 T 12-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily VAPA_1c45130 4499a97174fa660ec85f518ddfca9479 296 TIGRFAM TIGR00154 ispE: 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase 6 288 1.8E-64 T 12-10-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 VAPA_1c45130 4499a97174fa660ec85f518ddfca9479 296 Pfam PF08544 GHMP kinases C terminal 221 274 4.8E-7 T 12-10-2018 IPR013750 GHMP kinase, C-terminal domain VAPA_1c45130 4499a97174fa660ec85f518ddfca9479 296 Gene3D G3DSA:3.30.230.10 1 159 1.0E-54 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup VAPA_1c45130 4499a97174fa660ec85f518ddfca9479 296 Pfam PF00288 GHMP kinases N terminal domain 87 142 9.4E-8 T 12-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 VAPA_1c45130 4499a97174fa660ec85f518ddfca9479 296 SUPERFAMILY SSF54211 7 157 1.21E-40 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold VAPA_1c45130 4499a97174fa660ec85f518ddfca9479 296 Hamap MF_00061 Putative 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [ispE]. 5 283 30.332 T 12-10-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 VAPA_1c45130 4499a97174fa660ec85f518ddfca9479 296 PIRSF PIRSF010376 3 291 1.5E-80 T 12-10-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 VAPA_1c13610 9938d0f262e3dbe9da0099a61ebd9ec5 310 Gene3D G3DSA:3.40.50.720 15 310 4.8E-69 T 12-10-2018 VAPA_1c13610 9938d0f262e3dbe9da0099a61ebd9ec5 310 Pfam PF01370 NAD dependent epimerase/dehydratase family 22 225 3.4E-10 T 12-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 VAPA_1c13610 9938d0f262e3dbe9da0099a61ebd9ec5 310 SUPERFAMILY SSF51735 20 308 1.84E-36 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c28260 61e65206f21337eee4398db40ba22e16 401 Pfam PF13458 Periplasmic binding protein 49 392 6.3E-59 T 12-10-2018 IPR028081 Leucine-binding protein domain VAPA_1c28260 61e65206f21337eee4398db40ba22e16 401 Gene3D G3DSA:3.40.50.2300 170 302 2.3E-100 T 12-10-2018 VAPA_1c28260 61e65206f21337eee4398db40ba22e16 401 SUPERFAMILY SSF53822 49 392 2.98E-91 T 12-10-2018 IPR028082 Periplasmic binding protein-like I VAPA_1c28260 61e65206f21337eee4398db40ba22e16 401 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 71 87 7.0E-7 T 12-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 VAPA_1c28260 61e65206f21337eee4398db40ba22e16 401 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 49 65 7.0E-7 T 12-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 VAPA_1c28260 61e65206f21337eee4398db40ba22e16 401 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 280 298 7.0E-7 T 12-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 VAPA_1c28260 61e65206f21337eee4398db40ba22e16 401 Gene3D G3DSA:3.40.50.2300 50 375 2.3E-100 T 12-10-2018 VAPA_1c00840 d2baf0d0e062d8535510f71daebe28e7 679 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 548 557 - T 12-10-2018 IPR025944 Sigma-54 interaction domain, conserved site VAPA_1c00840 d2baf0d0e062d8535510f71daebe28e7 679 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 359 372 - T 12-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 VAPA_1c00840 d2baf0d0e062d8535510f71daebe28e7 679 SUPERFAMILY SSF52540 335 574 1.74E-62 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c00840 d2baf0d0e062d8535510f71daebe28e7 679 Gene3D G3DSA:3.30.450.40 20 207 1.0E-43 T 12-10-2018 IPR029016 GAF-like domain superfamily VAPA_1c00840 d2baf0d0e062d8535510f71daebe28e7 679 Gene3D G3DSA:3.40.50.300 327 507 6.6E-58 T 12-10-2018 VAPA_1c00840 d2baf0d0e062d8535510f71daebe28e7 679 SMART SM00382 355 499 6.8E-16 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c00840 d2baf0d0e062d8535510f71daebe28e7 679 SUPERFAMILY SSF55781 67 205 1.44E-5 T 12-10-2018 VAPA_1c00840 d2baf0d0e062d8535510f71daebe28e7 679 Gene3D G3DSA:1.10.8.60 510 578 3.1E-12 T 12-10-2018 VAPA_1c00840 d2baf0d0e062d8535510f71daebe28e7 679 Pfam PF00158 Sigma-54 interaction domain 335 499 2.8E-61 T 12-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 VAPA_1c00840 d2baf0d0e062d8535510f71daebe28e7 679 Pfam PF01590 GAF domain 87 193 2.1E-5 T 12-10-2018 IPR003018 GAF domain GO:0005515 VAPA_1c00490 239deb6d110241ea1aa1150aa1a8ced7 315 Gene3D G3DSA:3.90.1530.30 53 123 8.2E-25 T 12-10-2018 VAPA_1c00490 239deb6d110241ea1aa1150aa1a8ced7 315 SMART SM00470 40 137 1.9E-26 T 12-10-2018 IPR003115 ParB/Sulfiredoxin VAPA_1c00490 239deb6d110241ea1aa1150aa1a8ced7 315 Pfam PF02195 ParB-like nuclease domain 44 137 3.3E-20 T 12-10-2018 IPR003115 ParB/Sulfiredoxin VAPA_1c00490 239deb6d110241ea1aa1150aa1a8ced7 315 Gene3D G3DSA:1.10.10.2830 125 237 1.3E-35 T 12-10-2018 VAPA_1c00490 239deb6d110241ea1aa1150aa1a8ced7 315 SUPERFAMILY SSF110849 44 139 8.37E-24 T 12-10-2018 IPR036086 ParB/Sulfiredoxin superfamily VAPA_1c00490 239deb6d110241ea1aa1150aa1a8ced7 315 SUPERFAMILY SSF109709 130 237 2.88E-33 T 12-10-2018 VAPA_1c00490 239deb6d110241ea1aa1150aa1a8ced7 315 TIGRFAM TIGR00180 parB_part: ParB/RepB/Spo0J family partition protein 37 221 3.7E-51 T 12-10-2018 IPR004437 ParB/RepB/Spo0J partition protein family GO:0003677 VAPA_1c39140 fe25e0c91d862904b5e5a32b754e7a25 904 SUPERFAMILY SSF63737 15 198 3.4E-42 T 12-10-2018 VAPA_1c39140 fe25e0c91d862904b5e5a32b754e7a25 904 TIGRFAM TIGR02414 pepN_proteo: aminopeptidase N 18 901 0.0 T 12-10-2018 IPR012779 Peptidase M1, alanyl aminopeptidase GO:0008270 VAPA_1c39140 fe25e0c91d862904b5e5a32b754e7a25 904 Gene3D G3DSA:1.10.1740.60 202 285 8.7E-32 T 12-10-2018 VAPA_1c39140 fe25e0c91d862904b5e5a32b754e7a25 904 Gene3D G3DSA:2.60.40.1840 459 570 1.5E-29 T 12-10-2018 IPR038438 Alanyl aminopeptidase, Ig-like domain superfamily VAPA_1c39140 fe25e0c91d862904b5e5a32b754e7a25 904 SUPERFAMILY SSF55486 213 463 5.13E-67 T 12-10-2018 VAPA_1c39140 fe25e0c91d862904b5e5a32b754e7a25 904 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 182 197 3.6E-8 T 12-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 VAPA_1c39140 fe25e0c91d862904b5e5a32b754e7a25 904 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 132 147 3.6E-8 T 12-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 VAPA_1c39140 fe25e0c91d862904b5e5a32b754e7a25 904 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 300 315 3.6E-8 T 12-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 VAPA_1c39140 fe25e0c91d862904b5e5a32b754e7a25 904 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 264 274 3.6E-8 T 12-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 VAPA_1c39140 fe25e0c91d862904b5e5a32b754e7a25 904 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 319 331 3.6E-8 T 12-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 VAPA_1c39140 fe25e0c91d862904b5e5a32b754e7a25 904 Pfam PF17432 Domain of unknown function (DUF3458_C) ARM repeats 573 902 7.0E-116 T 12-10-2018 IPR024601 Peptidase M1, alanyl aminopeptidase, C-terminal VAPA_1c39140 fe25e0c91d862904b5e5a32b754e7a25 904 Gene3D G3DSA:2.60.40.1730 21 200 1.7E-69 T 12-10-2018 VAPA_1c39140 fe25e0c91d862904b5e5a32b754e7a25 904 Pfam PF01433 Peptidase family M1 domain 216 439 8.7E-52 T 12-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 VAPA_1c39140 fe25e0c91d862904b5e5a32b754e7a25 904 Gene3D G3DSA:1.10.390.10 286 458 1.4E-61 T 12-10-2018 IPR027268 Peptidase M4/M1, CTD superfamily VAPA_1c39140 fe25e0c91d862904b5e5a32b754e7a25 904 Gene3D G3DSA:1.25.50.10 571 902 3.4E-110 T 12-10-2018 IPR037144 Peptidase M1, alanyl aminopeptidase, C-terminal domain superfamily VAPA_1c39140 fe25e0c91d862904b5e5a32b754e7a25 904 Pfam PF11940 Domain of unknown function (DUF3458) Ig-like fold 459 569 7.8E-26 T 12-10-2018 IPR035414 Peptidase M1, alanyl aminopeptidase, Ig-like fold VAPA_1c52900 49d5c2c32d4ecc96f615e4a8b9d48b6c 338 Gene3D G3DSA:3.40.50.1100 67 165 4.0E-120 T 12-10-2018 VAPA_1c52900 49d5c2c32d4ecc96f615e4a8b9d48b6c 338 SUPERFAMILY SSF53686 5 332 4.25E-98 T 12-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme VAPA_1c52900 49d5c2c32d4ecc96f615e4a8b9d48b6c 338 TIGRFAM TIGR01274 ACC_deam: 1-aminocyclopropane-1-carboxylate deaminase 2 337 3.0E-190 T 12-10-2018 IPR005965 1-aminocyclopropane-1-carboxylate deaminase GO:0008660|GO:0009310|GO:0030170 KEGG: 00270+3.5.99.7 VAPA_1c52900 49d5c2c32d4ecc96f615e4a8b9d48b6c 338 PIRSF PIRSF006278 1 338 5.2E-119 T 12-10-2018 IPR027278 1-aminocyclopropane-1-carboxylate deaminase/D-cysteine desulfhydrase VAPA_1c52900 49d5c2c32d4ecc96f615e4a8b9d48b6c 338 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 12 321 4.0E-42 T 12-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme VAPA_1c52900 49d5c2c32d4ecc96f615e4a8b9d48b6c 338 Hamap MF_00807 1-aminocyclopropane-1-carboxylate deaminase [acdS]. 2 338 71.423 T 12-10-2018 IPR020601 1-aminocyclopropane-1-carboxylate deaminase, bacterial GO:0008660|GO:0009310|GO:0030170 KEGG: 00270+3.5.99.7 VAPA_1c52900 49d5c2c32d4ecc96f615e4a8b9d48b6c 338 Gene3D G3DSA:3.40.50.1100 8 328 4.0E-120 T 12-10-2018 VAPA_1c01270 0f6424dabe12f6aa5b8520fd92e79eaa 399 SUPERFAMILY SSF47203 244 393 6.44E-41 T 12-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 VAPA_1c01270 0f6424dabe12f6aa5b8520fd92e79eaa 399 SUPERFAMILY SSF56645 7 243 4.32E-76 T 12-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 VAPA_1c01270 0f6424dabe12f6aa5b8520fd92e79eaa 399 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 245 391 2.7E-28 T 12-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 VAPA_1c01270 0f6424dabe12f6aa5b8520fd92e79eaa 399 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 136 232 2.3E-19 T 12-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 VAPA_1c01270 0f6424dabe12f6aa5b8520fd92e79eaa 399 Gene3D G3DSA:1.20.140.10 246 399 1.2E-41 T 12-10-2018 VAPA_1c01270 0f6424dabe12f6aa5b8520fd92e79eaa 399 Gene3D G3DSA:2.40.110.10 135 244 2.4E-35 T 12-10-2018 VAPA_1c01270 0f6424dabe12f6aa5b8520fd92e79eaa 399 Gene3D G3DSA:1.10.540.10 2 134 1.0E-42 T 12-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 VAPA_1c01270 0f6424dabe12f6aa5b8520fd92e79eaa 399 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 350 369 - T 12-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 VAPA_1c01270 0f6424dabe12f6aa5b8520fd92e79eaa 399 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 20 132 7.0E-34 T 12-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 VAPA_2c03110 217fe99d2875e5583ef5b40c302d4187 272 SUPERFAMILY SSF53850 62 236 5.43E-10 T 12-10-2018 VAPA_2c03110 217fe99d2875e5583ef5b40c302d4187 272 Gene3D G3DSA:3.40.190.150 3 262 5.2E-91 T 12-10-2018 VAPA_2c03110 217fe99d2875e5583ef5b40c302d4187 272 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 5 268 3.5E-79 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_2c03110 217fe99d2875e5583ef5b40c302d4187 272 Gene3D G3DSA:3.40.190.10 74 197 5.2E-91 T 12-10-2018 VAPA_2c05870 29fb7e512550765599ccaffbe989a237 286 SUPERFAMILY SSF54637 170 284 5.87E-15 T 12-10-2018 IPR029069 HotDog domain superfamily VAPA_2c05870 29fb7e512550765599ccaffbe989a237 286 SUPERFAMILY SSF54637 77 159 2.35E-7 T 12-10-2018 IPR029069 HotDog domain superfamily VAPA_2c05870 29fb7e512550765599ccaffbe989a237 286 Gene3D G3DSA:3.10.129.10 35 159 5.7E-14 T 12-10-2018 VAPA_2c05870 29fb7e512550765599ccaffbe989a237 286 Gene3D G3DSA:3.10.129.10 170 285 2.0E-13 T 12-10-2018 VAPA_2c05870 29fb7e512550765599ccaffbe989a237 286 Pfam PF13452 N-terminal half of MaoC dehydratase 76 132 6.6E-11 T 12-10-2018 IPR039569 N-terminal of MaoC-like dehydratase Reactome: R-HSA-193368|Reactome: R-HSA-2046106|Reactome: R-HSA-389887|Reactome: R-HSA-390247|Reactome: R-HSA-9033241|Reactome: R-HSA-9033500 VAPA_1c20950 d7e12875a67dc04e60ff54b970e2f71a 164 SMART SM00226 3 144 2.2E-33 T 12-10-2018 IPR023485 Phosphotyrosine protein phosphatase I VAPA_1c20950 d7e12875a67dc04e60ff54b970e2f71a 164 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 5 142 4.0E-16 T 12-10-2018 IPR023485 Phosphotyrosine protein phosphatase I VAPA_1c20950 d7e12875a67dc04e60ff54b970e2f71a 164 Gene3D G3DSA:3.40.50.2300 2 144 1.1E-37 T 12-10-2018 VAPA_1c20950 d7e12875a67dc04e60ff54b970e2f71a 164 SUPERFAMILY SSF52788 3 144 1.57E-36 T 12-10-2018 IPR036196 Phosphotyrosine protein phosphatase I superfamily VAPA_1c00880 719b369e4d549ffb990704be8200b6ce 290 Pfam PF02653 Branched-chain amino acid transport system / permease component 11 278 3.9E-42 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 VAPA_2c11280 ab07554a26a3cb0894b93ce6e5aaf9e9 630 Pfam PF12482 Phage integrase protein 143 234 2.7E-24 T 12-10-2018 IPR022169 Protein of unknown function DUF3701 VAPA_2c11280 ab07554a26a3cb0894b93ce6e5aaf9e9 630 Pfam PF00589 Phage integrase family 423 620 3.3E-14 T 12-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 VAPA_2c11280 ab07554a26a3cb0894b93ce6e5aaf9e9 630 SUPERFAMILY SSF56349 302 619 8.24E-25 T 12-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 VAPA_2c11280 ab07554a26a3cb0894b93ce6e5aaf9e9 630 Gene3D G3DSA:1.10.443.10 420 627 3.6E-24 T 12-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 VAPA_2c03920 a473eb8725e428ec2b040dc3f9f9faea 82 SUPERFAMILY SSF51230 5 79 1.09E-11 T 12-10-2018 IPR011053 Single hybrid motif VAPA_2c03920 a473eb8725e428ec2b040dc3f9f9faea 82 Gene3D G3DSA:2.40.50.100 4 80 3.1E-17 T 12-10-2018 VAPA_2c03920 a473eb8725e428ec2b040dc3f9f9faea 82 Pfam PF00364 Biotin-requiring enzyme 17 78 3.6E-10 T 12-10-2018 IPR000089 Biotin/lipoyl attachment VAPA_1c28310 ad912007294ae5db088ef132cb1c7b11 369 TIGRFAM TIGR04408 LptG_lptG: LPS export ABC transporter permease LptG 3 364 5.6E-101 T 12-10-2018 IPR030923 LPS export ABC transporter permease LptG GO:0043190|GO:0055085 VAPA_1c28310 ad912007294ae5db088ef132cb1c7b11 369 Pfam PF03739 Predicted permease YjgP/YjgQ family 6 361 4.0E-60 T 12-10-2018 IPR005495 Permease LptG/LptF-related GO:0016021 VAPA_2c02870 675799900ffbeb218f7db06e3798be85 333 Gene3D G3DSA:3.40.190.150 39 323 1.5E-101 T 12-10-2018 VAPA_2c02870 675799900ffbeb218f7db06e3798be85 333 SUPERFAMILY SSF53850 128 293 7.24E-9 T 12-10-2018 VAPA_2c02870 675799900ffbeb218f7db06e3798be85 333 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 58 329 5.6E-80 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_2c02870 675799900ffbeb218f7db06e3798be85 333 PIRSF PIRSF017082 1 333 2.0E-75 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_2c02870 675799900ffbeb218f7db06e3798be85 333 Gene3D G3DSA:3.40.190.10 135 258 1.5E-101 T 12-10-2018 VAPA_1c41360 c4e64c0248efbdf2d787400b5ef1d603 173 Gene3D G3DSA:3.90.1720.10 25 169 1.1E-36 T 12-10-2018 VAPA_1c41360 c4e64c0248efbdf2d787400b5ef1d603 173 SUPERFAMILY SSF54001 54 173 6.38E-36 T 12-10-2018 IPR038765 Papain-like cysteine peptidase superfamily VAPA_1c41360 c4e64c0248efbdf2d787400b5ef1d603 173 Pfam PF00877 NlpC/P60 family 67 172 5.9E-25 T 12-10-2018 IPR000064 Endopeptidase, NLPC/P60 domain VAPA_1c47420 4feab70eb621800ab3e866e37e362afd 1079 SUPERFAMILY SSF53335 196 702 2.37E-36 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase VAPA_1c47420 4feab70eb621800ab3e866e37e362afd 1079 Gene3D G3DSA:3.40.50.150 299 713 3.3E-42 T 12-10-2018 VAPA_1c47420 4feab70eb621800ab3e866e37e362afd 1079 Pfam PF02384 N-6 DNA Methylase 298 512 4.6E-8 T 12-10-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 VAPA_1c47420 4feab70eb621800ab3e866e37e362afd 1079 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 384 398 2.3E-10 T 12-10-2018 VAPA_1c47420 4feab70eb621800ab3e866e37e362afd 1079 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 499 511 2.3E-10 T 12-10-2018 VAPA_1c47420 4feab70eb621800ab3e866e37e362afd 1079 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 321 337 2.3E-10 T 12-10-2018 VAPA_2c09840 4f66769220c30e39dcbd6ed17077a7b9 416 Pfam PF02515 CoA-transferase family III 24 393 3.1E-112 T 12-10-2018 IPR003673 CoA-transferase family III GO:0003824 VAPA_2c09840 4f66769220c30e39dcbd6ed17077a7b9 416 Gene3D G3DSA:3.40.50.10540 23 410 2.1E-116 T 12-10-2018 IPR023606 CoA-transferase family III domain superfamily VAPA_2c09840 4f66769220c30e39dcbd6ed17077a7b9 416 SUPERFAMILY SSF89796 22 416 4.06E-119 T 12-10-2018 IPR023606 CoA-transferase family III domain superfamily VAPA_2c09840 4f66769220c30e39dcbd6ed17077a7b9 416 Gene3D G3DSA:3.30.1540.10 252 344 2.1E-116 T 12-10-2018 VAPA_1c45860 61cbc713c17d84c95566932e2c199280 119 PIRSF PIRSF007028 2 119 8.5E-54 T 12-10-2018 IPR009874 Protein of unknown function DUF1428 VAPA_1c45860 61cbc713c17d84c95566932e2c199280 119 Gene3D G3DSA:3.30.70.100 1 119 1.2E-44 T 12-10-2018 VAPA_1c45860 61cbc713c17d84c95566932e2c199280 119 Pfam PF07237 Protein of unknown function (DUF1428) 4 105 1.6E-43 T 12-10-2018 IPR009874 Protein of unknown function DUF1428 VAPA_1c45860 61cbc713c17d84c95566932e2c199280 119 SUPERFAMILY SSF54909 3 118 1.18E-46 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel VAPA_2c06870 f391dfadf08c8eda07168cb08c6f339f 262 ProSitePatterns PS00894 DeoR-type HTH domain signature. 13 47 - T 12-10-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 VAPA_2c06870 f391dfadf08c8eda07168cb08c6f339f 262 SMART SM00420 13 62 5.6E-6 T 12-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 VAPA_2c06870 f391dfadf08c8eda07168cb08c6f339f 262 SUPERFAMILY SSF100950 81 235 9.77E-24 T 12-10-2018 IPR037171 NagB/RpiA transferase-like VAPA_2c06870 f391dfadf08c8eda07168cb08c6f339f 262 Pfam PF00455 DeoR C terminal sensor domain 81 237 6.0E-40 T 12-10-2018 IPR014036 DeoR C-terminal sensor domain VAPA_2c06870 f391dfadf08c8eda07168cb08c6f339f 262 SMART SM01134 79 240 6.6E-52 T 12-10-2018 VAPA_2c06870 f391dfadf08c8eda07168cb08c6f339f 262 Pfam PF08220 DeoR-like helix-turn-helix domain 13 49 2.9E-8 T 12-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 VAPA_2c07180 528076308f1161b3e6bf91489767d0b1 334 SUPERFAMILY SSF103481 220 320 7.59E-14 T 12-10-2018 VAPA_2c07180 528076308f1161b3e6bf91489767d0b1 334 SUPERFAMILY SSF103481 69 168 4.58E-15 T 12-10-2018 VAPA_2c07180 528076308f1161b3e6bf91489767d0b1 334 Pfam PF00892 EamA-like transporter family 38 168 1.5E-14 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 VAPA_2c07180 528076308f1161b3e6bf91489767d0b1 334 Pfam PF00892 EamA-like transporter family 187 314 2.4E-14 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 VAPA_1c45310 736b4c9df0eee494741a19ef7d9a6a1a 132 Gene3D G3DSA:3.30.429.10 1 60 8.3E-8 T 12-10-2018 IPR014347 Tautomerase/MIF superfamily VAPA_1c45310 736b4c9df0eee494741a19ef7d9a6a1a 132 Gene3D G3DSA:3.30.429.10 67 129 6.6E-7 T 12-10-2018 IPR014347 Tautomerase/MIF superfamily VAPA_1c45310 736b4c9df0eee494741a19ef7d9a6a1a 132 Pfam PF01361 Tautomerase enzyme 2 59 6.4E-5 T 12-10-2018 IPR004370 4-oxalocrotonate tautomerase GO:0006725|GO:0016853 VAPA_1c45310 736b4c9df0eee494741a19ef7d9a6a1a 132 SUPERFAMILY SSF55331 2 125 9.6E-18 T 12-10-2018 IPR014347 Tautomerase/MIF superfamily VAPA_2c02660 b9fe5709186500aacdee7fbf31f40796 467 PIRSF PIRSF000521 36 455 1.8E-30 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 VAPA_2c02660 b9fe5709186500aacdee7fbf31f40796 467 Gene3D G3DSA:3.90.1150.10 17 453 3.3E-152 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 VAPA_2c02660 b9fe5709186500aacdee7fbf31f40796 467 Gene3D G3DSA:3.40.640.10 71 349 3.3E-152 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 VAPA_2c02660 b9fe5709186500aacdee7fbf31f40796 467 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 259 296 - T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 VAPA_2c02660 b9fe5709186500aacdee7fbf31f40796 467 Pfam PF00202 Aminotransferase class-III 36 452 1.6E-94 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 VAPA_2c02660 b9fe5709186500aacdee7fbf31f40796 467 SUPERFAMILY SSF53383 17 454 7.2E-117 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase VAPA_2c11850 4fa8b20f6a79a958745495f793547ef5 92 Pfam PF02426 Muconolactone delta-isomerase 1 89 6.8E-43 T 12-10-2018 IPR026029 Muconolactone isomerase domain KEGG: 00362+5.3.3.4|MetaCyc: PWY-6185 VAPA_2c11850 4fa8b20f6a79a958745495f793547ef5 92 PIRSF PIRSF001486 1 92 8.3E-48 T 12-10-2018 IPR003464 Muconolactone delta-isomerase GO:0006725 KEGG: 00362+5.3.3.4|MetaCyc: PWY-6185 VAPA_2c11850 4fa8b20f6a79a958745495f793547ef5 92 Gene3D G3DSA:3.30.70.1060 1 92 3.9E-39 T 12-10-2018 VAPA_2c11850 4fa8b20f6a79a958745495f793547ef5 92 TIGRFAM TIGR03221 muco_delta: muconolactone delta-isomerase 2 91 2.3E-48 T 12-10-2018 IPR003464 Muconolactone delta-isomerase GO:0006725 KEGG: 00362+5.3.3.4|MetaCyc: PWY-6185 VAPA_2c11850 4fa8b20f6a79a958745495f793547ef5 92 SUPERFAMILY SSF54909 1 91 2.68E-39 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel VAPA_2c11850 4fa8b20f6a79a958745495f793547ef5 92 ProDom PD006619 ISOMERASE MUCONOLACTONE DELTA-ISOMERASE HYDROCARBONS MIASE AROMATIC CATABOLISM METHYLMUCONOLACTONE DIRECT SEQUENCING 1 57 4.0E-21 T 12-10-2018 IPR003464 Muconolactone delta-isomerase GO:0006725 KEGG: 00362+5.3.3.4|MetaCyc: PWY-6185 VAPA_1c31400 ef5bac521218afab61009a2ff4e8dc51 217 Pfam PF02441 Flavoprotein 36 149 1.9E-12 T 12-10-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 VAPA_1c31400 ef5bac521218afab61009a2ff4e8dc51 217 Gene3D G3DSA:3.40.50.1950 33 211 9.4E-49 T 12-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 VAPA_1c31400 ef5bac521218afab61009a2ff4e8dc51 217 SUPERFAMILY SSF52507 35 196 1.7E-17 T 12-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 VAPA_1c22300 71a6148b5fe1129a88052e53cd1e7b35 290 TIGRFAM TIGR01183 ntrB: nitrate ABC transporter, permease protein 83 279 1.4E-66 T 12-10-2018 IPR005889 Nitrate transport permease GO:0015112|GO:0015706|GO:0016021 VAPA_1c22300 71a6148b5fe1129a88052e53cd1e7b35 290 SUPERFAMILY SSF161098 95 279 1.57E-21 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c22300 71a6148b5fe1129a88052e53cd1e7b35 290 Gene3D G3DSA:1.10.3720.10 98 287 9.7E-16 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c22300 71a6148b5fe1129a88052e53cd1e7b35 290 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 117 280 1.1E-15 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 VAPA_1c30500 52848555df76f9e1e3798128c1043b6e 614 Pfam PF02705 K+ potassium transporter 2 537 2.3E-199 T 12-10-2018 IPR003855 Potassium transporter GO:0015079|GO:0016020|GO:0071805 VAPA_1c30500 52848555df76f9e1e3798128c1043b6e 614 Hamap MF_01522 Low affinity potassium transport system protein kup [kup]. 1 614 31.117 T 12-10-2018 IPR023051 Potassium uptake protein, low affinity, Kup VAPA_1c13770 f23ec1fb9e6c0d3efaa3a3567e3e6f66 292 PIRSF PIRSF004750 10 292 7.7E-115 T 12-10-2018 IPR016428 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 2 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 VAPA_1c13770 f23ec1fb9e6c0d3efaa3a3567e3e6f66 292 Gene3D G3DSA:3.30.1130.10 25 143 1.7E-38 T 12-10-2018 VAPA_1c13770 f23ec1fb9e6c0d3efaa3a3567e3e6f66 292 Pfam PF14819 Nitrile reductase, 7-cyano-7-deazaguanine-reductase N-term 25 126 2.1E-43 T 12-10-2018 IPR029139 NADPH-dependent 7-cyano-7-deazaguanine reductase, N-terminal KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 VAPA_1c13770 f23ec1fb9e6c0d3efaa3a3567e3e6f66 292 Gene3D G3DSA:3.30.1130.10 155 292 2.6E-55 T 12-10-2018 VAPA_1c13770 f23ec1fb9e6c0d3efaa3a3567e3e6f66 292 Hamap MF_00817 NADPH-dependent 7-cyano-7-deazaguanine reductase [queF]. 1 292 148.491 T 12-10-2018 IPR016428 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 2 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 VAPA_1c13770 f23ec1fb9e6c0d3efaa3a3567e3e6f66 292 Pfam PF14489 QueF-like protein 205 278 6.6E-24 T 12-10-2018 IPR029500 NADPH-dependent 7-cyano-7-deazaguanine reductase QueF GO:0008616|GO:0033739 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 VAPA_1c13770 f23ec1fb9e6c0d3efaa3a3567e3e6f66 292 SUPERFAMILY SSF55620 195 278 1.04E-7 T 12-10-2018 VAPA_1c13770 f23ec1fb9e6c0d3efaa3a3567e3e6f66 292 TIGRFAM TIGR03138 QueF: queuine synthase 14 292 9.8E-116 T 12-10-2018 IPR016428 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 2 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 VAPA_2c00270 547ee15499f89650a0c3c71286821f9d 374 TIGRFAM TIGR03408 urea_trans_UrtC: urea ABC transporter, permease protein UrtC 25 353 3.0E-103 T 12-10-2018 IPR017778 ABC transporter, urea, permease protein, UrtC VAPA_2c00270 547ee15499f89650a0c3c71286821f9d 374 Pfam PF02653 Branched-chain amino acid transport system / permease component 34 343 8.6E-41 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 VAPA_1c25640 5bb898554877bf2d9eb5b17cf6edc620 390 Pfam PF01266 FAD dependent oxidoreductase 3 359 8.9E-54 T 12-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 VAPA_1c25640 5bb898554877bf2d9eb5b17cf6edc620 390 Gene3D G3DSA:3.50.50.60 4 360 2.7E-94 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c25640 5bb898554877bf2d9eb5b17cf6edc620 390 Gene3D G3DSA:3.30.9.10 92 318 2.7E-94 T 12-10-2018 VAPA_1c25640 5bb898554877bf2d9eb5b17cf6edc620 390 SUPERFAMILY SSF51905 3 381 1.17E-41 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c38390 db6024136e2bfe47ae141f8f9dbf05ff 403 SUPERFAMILY SSF48452 204 278 8.54E-5 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 VAPA_1c38390 db6024136e2bfe47ae141f8f9dbf05ff 403 Pfam PF00691 OmpA family 291 384 3.1E-9 T 12-10-2018 IPR006665 OmpA-like domain VAPA_1c38390 db6024136e2bfe47ae141f8f9dbf05ff 403 PRINTS PR01021 OMPA domain signature 341 357 3.2E-5 T 12-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 VAPA_1c38390 db6024136e2bfe47ae141f8f9dbf05ff 403 PRINTS PR01021 OMPA domain signature 326 341 3.2E-5 T 12-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 VAPA_1c38390 db6024136e2bfe47ae141f8f9dbf05ff 403 Gene3D G3DSA:3.30.1330.60 269 402 4.1E-14 T 12-10-2018 IPR036737 OmpA-like domain superfamily VAPA_1c38390 db6024136e2bfe47ae141f8f9dbf05ff 403 SUPERFAMILY SSF103088 285 400 1.26E-15 T 12-10-2018 IPR036737 OmpA-like domain superfamily VAPA_1c40290 57353535cb5d212794868c947c160122 439 TIGRFAM TIGR01426 MGT: glycosyltransferase, MGT family 11 415 3.4E-35 T 12-10-2018 IPR006326 UDP-glycosyltransferase, MGT GO:0016758|GO:0016999 VAPA_1c40290 57353535cb5d212794868c947c160122 439 Gene3D G3DSA:3.40.50.2000 250 412 6.9E-44 T 12-10-2018 VAPA_1c40290 57353535cb5d212794868c947c160122 439 SUPERFAMILY SSF53756 5 426 2.3E-75 T 12-10-2018 VAPA_1c40290 57353535cb5d212794868c947c160122 439 Pfam PF00201 UDP-glucoronosyl and UDP-glucosyl transferase 215 408 7.1E-12 T 12-10-2018 IPR002213 UDP-glucuronosyl/UDP-glucosyltransferase GO:0016758 Reactome: R-HSA-156588 VAPA_1c40290 57353535cb5d212794868c947c160122 439 Gene3D G3DSA:3.40.50.2000 1 249 4.9E-37 T 12-10-2018 VAPA_1c35540 c54dcdeeb73ca2512a3d2a5d16b71179 92 Pfam PF04977 Septum formation initiator 14 90 8.0E-21 T 12-10-2018 IPR007060 Septum formation initiator FtsL/DivIC VAPA_1c35540 c54dcdeeb73ca2512a3d2a5d16b71179 92 Hamap MF_00599 Cell division protein FtsB [ftsB]. 1 92 26.735 T 12-10-2018 IPR023081 Cell division protein FtsB VAPA_1c40120 fb39659ddfdf33f913dfdbc1828e821d 332 SUPERFAMILY SSF52317 18 208 1.44E-47 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like VAPA_1c40120 fb39659ddfdf33f913dfdbc1828e821d 332 SUPERFAMILY SSF46689 280 328 1.43E-9 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 VAPA_1c40120 fb39659ddfdf33f913dfdbc1828e821d 332 Pfam PF12833 Helix-turn-helix domain 250 328 1.6E-18 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 VAPA_1c40120 fb39659ddfdf33f913dfdbc1828e821d 332 SMART SM00342 244 327 8.3E-26 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 VAPA_1c40120 fb39659ddfdf33f913dfdbc1828e821d 332 Gene3D G3DSA:1.10.10.60 227 331 2.4E-27 T 12-10-2018 VAPA_1c40120 fb39659ddfdf33f913dfdbc1828e821d 332 SUPERFAMILY SSF46689 228 275 8.71E-10 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 VAPA_1c40120 fb39659ddfdf33f913dfdbc1828e821d 332 Gene3D G3DSA:3.40.50.880 11 217 1.5E-60 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like VAPA_1c40120 fb39659ddfdf33f913dfdbc1828e821d 332 Pfam PF01965 DJ-1/PfpI family 18 188 2.5E-26 T 12-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 VAPA_1c01830 b2ecbe8362619fba2f80800a7b24203a 775 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 568 689 9.0E-30 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 VAPA_1c01830 b2ecbe8362619fba2f80800a7b24203a 775 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 314 451 2.6E-14 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 VAPA_1c01830 b2ecbe8362619fba2f80800a7b24203a 775 SMART SM00382 564 694 3.7E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c01830 b2ecbe8362619fba2f80800a7b24203a 775 SMART SM00382 310 455 4.9E-9 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c01830 b2ecbe8362619fba2f80800a7b24203a 775 SUPERFAMILY SSF52540 555 723 9.57E-33 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c01830 b2ecbe8362619fba2f80800a7b24203a 775 SUPERFAMILY SSF52540 294 505 1.21E-25 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c01830 b2ecbe8362619fba2f80800a7b24203a 775 Gene3D G3DSA:3.40.50.300 281 470 2.5E-24 T 12-10-2018 VAPA_1c01830 b2ecbe8362619fba2f80800a7b24203a 775 Gene3D G3DSA:3.40.50.300 537 713 1.3E-38 T 12-10-2018 VAPA_1c04440 020d789aef795c0209846098d7cb59a4 401 SUPERFAMILY SSF53822 35 396 4.0E-83 T 12-10-2018 IPR028082 Periplasmic binding protein-like I VAPA_1c04440 020d789aef795c0209846098d7cb59a4 401 Gene3D G3DSA:3.40.50.2300 36 363 3.0E-92 T 12-10-2018 VAPA_1c04440 020d789aef795c0209846098d7cb59a4 401 Pfam PF13458 Periplasmic binding protein 35 368 3.3E-69 T 12-10-2018 IPR028081 Leucine-binding protein domain VAPA_1c04440 020d789aef795c0209846098d7cb59a4 401 Gene3D G3DSA:3.40.50.2300 153 372 3.0E-92 T 12-10-2018 VAPA_1c24460 9cc9aa015e698e55a9b19008811ad1c9 710 Gene3D G3DSA:3.30.1840.10 10 319 3.6E-88 T 12-10-2018 IPR036830 Polyphosphate kinase middle domain superfamily KEGG: 00190+2.7.4.1 VAPA_1c24460 9cc9aa015e698e55a9b19008811ad1c9 710 TIGRFAM TIGR03705 poly_P_kin: polyphosphate kinase 1 17 675 3.2E-260 T 12-10-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 VAPA_1c24460 9cc9aa015e698e55a9b19008811ad1c9 710 Gene3D G3DSA:3.30.870.10 327 509 7.9E-67 T 12-10-2018 VAPA_1c24460 9cc9aa015e698e55a9b19008811ad1c9 710 SUPERFAMILY SSF56024 508 674 1.75E-59 T 12-10-2018 VAPA_1c24460 9cc9aa015e698e55a9b19008811ad1c9 710 SUPERFAMILY SSF143724 116 321 1.08E-59 T 12-10-2018 VAPA_1c24460 9cc9aa015e698e55a9b19008811ad1c9 710 Hamap MF_00347 Polyphosphate kinase [ppk]. 14 700 25.88 T 12-10-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 VAPA_1c24460 9cc9aa015e698e55a9b19008811ad1c9 710 Gene3D G3DSA:3.30.870.10 512 686 2.0E-56 T 12-10-2018 VAPA_1c24460 9cc9aa015e698e55a9b19008811ad1c9 710 SUPERFAMILY SSF56024 323 501 1.92E-54 T 12-10-2018 VAPA_1c24460 9cc9aa015e698e55a9b19008811ad1c9 710 PIRSF PIRSF015589 2 705 7.7E-236 T 12-10-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 VAPA_1c24460 9cc9aa015e698e55a9b19008811ad1c9 710 Pfam PF13090 Polyphosphate kinase C-terminal domain 339 673 1.4E-138 T 12-10-2018 IPR025200 Polyphosphate kinase C-terminal domain KEGG: 00190+2.7.4.1 VAPA_1c24460 9cc9aa015e698e55a9b19008811ad1c9 710 SUPERFAMILY SSF140356 17 114 9.42E-28 T 12-10-2018 IPR036832 Polyphosphate kinase N-terminal domain superfamily KEGG: 00190+2.7.4.1 VAPA_1c24460 9cc9aa015e698e55a9b19008811ad1c9 710 Pfam PF02503 Polyphosphate kinase middle domain 128 326 1.2E-55 T 12-10-2018 IPR024953 Polyphosphate kinase middle domain KEGG: 00190+2.7.4.1 VAPA_1c24460 9cc9aa015e698e55a9b19008811ad1c9 710 Pfam PF13089 Polyphosphate kinase N-terminal domain 18 119 1.3E-28 T 12-10-2018 IPR025198 Polyphosphate kinase N-terminal domain KEGG: 00190+2.7.4.1 VAPA_1c37280 154c92791d5c3f7040f3767b742125a7 496 Gene3D G3DSA:2.20.200.10 118 363 8.9E-123 T 12-10-2018 VAPA_1c37280 154c92791d5c3f7040f3767b742125a7 496 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 24 474 2.3E-114 T 12-10-2018 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0016020|GO:0022857|GO:0055085 VAPA_1c37280 154c92791d5c3f7040f3767b742125a7 496 Gene3D G3DSA:1.20.1600.10 71 475 8.9E-123 T 12-10-2018 VAPA_1c37280 154c92791d5c3f7040f3767b742125a7 496 Pfam PF02321 Outer membrane efflux protein 291 472 2.7E-22 T 12-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 VAPA_1c37280 154c92791d5c3f7040f3767b742125a7 496 Pfam PF02321 Outer membrane efflux protein 81 265 7.7E-28 T 12-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 VAPA_1c37280 154c92791d5c3f7040f3767b742125a7 496 SUPERFAMILY SSF56954 11 476 3.27E-103 T 12-10-2018 VAPA_1c49520 a8f0417e9294126ece147492b0f46dce 353 TIGRFAM TIGR03082 Gneg_AbrB_dup: membrane protein AbrB duplication 193 349 7.5E-37 T 12-10-2018 IPR017516 AbrB duplication VAPA_1c49520 a8f0417e9294126ece147492b0f46dce 353 PIRSF PIRSF038991 2 353 1.8E-85 T 12-10-2018 IPR007820 AbrB family GO:0010468|GO:0016021 VAPA_1c49520 a8f0417e9294126ece147492b0f46dce 353 Pfam PF05145 Transition state regulatory protein AbrB 32 349 1.3E-79 T 12-10-2018 IPR007820 AbrB family GO:0010468|GO:0016021 VAPA_1c13070 bffb1efae3274943f83485f8418b77f3 345 SMART SM00327 85 306 5.5E-16 T 12-10-2018 IPR002035 von Willebrand factor, type A VAPA_1c13070 bffb1efae3274943f83485f8418b77f3 345 SUPERFAMILY SSF53300 84 307 4.32E-28 T 12-10-2018 IPR036465 von Willebrand factor A-like domain superfamily VAPA_1c13070 bffb1efae3274943f83485f8418b77f3 345 Pfam PF07584 Aerotolerance regulator N-terminal 1 75 1.8E-9 T 12-10-2018 IPR024163 Aerotolerance regulator, N-terminal VAPA_1c13070 bffb1efae3274943f83485f8418b77f3 345 Pfam PF13519 von Willebrand factor type A domain 88 175 1.2E-15 T 12-10-2018 IPR002035 von Willebrand factor, type A VAPA_1c13070 bffb1efae3274943f83485f8418b77f3 345 Pfam PF00092 von Willebrand factor type A domain 218 303 3.4E-8 T 12-10-2018 IPR002035 von Willebrand factor, type A VAPA_1c10890 d4e64ff0f102072e27515bf813c802b4 330 SUPERFAMILY SSF103481 200 300 2.48E-8 T 12-10-2018 VAPA_1c10890 d4e64ff0f102072e27515bf813c802b4 330 SUPERFAMILY SSF103481 50 142 7.45E-8 T 12-10-2018 VAPA_1c10890 d4e64ff0f102072e27515bf813c802b4 330 Pfam PF00892 EamA-like transporter family 8 142 2.9E-15 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 VAPA_1c10890 d4e64ff0f102072e27515bf813c802b4 330 Pfam PF00892 EamA-like transporter family 186 294 1.9E-7 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 VAPA_1c50780 5078990c59bd83a8ea13053e74a9da5f 598 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 280 573 1.8E-101 T 12-10-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 VAPA_1c50780 5078990c59bd83a8ea13053e74a9da5f 598 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 211 222 - T 12-10-2018 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 VAPA_1c50780 5078990c59bd83a8ea13053e74a9da5f 598 Gene3D G3DSA:1.10.274.10 24 173 9.8E-73 T 12-10-2018 IPR036618 PtsI, HPr-binding domain superfamily GO:0009401 VAPA_1c50780 5078990c59bd83a8ea13053e74a9da5f 598 SUPERFAMILY SSF51621 278 581 1.39E-96 T 12-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 VAPA_1c50780 5078990c59bd83a8ea13053e74a9da5f 598 Gene3D G3DSA:3.50.30.10 7 260 9.8E-73 T 12-10-2018 VAPA_1c50780 5078990c59bd83a8ea13053e74a9da5f 598 Pfam PF05524 PEP-utilising enzyme, N-terminal 6 133 2.6E-29 T 12-10-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 VAPA_1c50780 5078990c59bd83a8ea13053e74a9da5f 598 SUPERFAMILY SSF47831 27 150 7.98E-29 T 12-10-2018 IPR036618 PtsI, HPr-binding domain superfamily GO:0009401 VAPA_1c50780 5078990c59bd83a8ea13053e74a9da5f 598 PIRSF PIRSF000732 1 596 2.3E-195 T 12-10-2018 IPR024692 Phosphotransferase system, enzyme I GO:0008965|GO:0009401 VAPA_1c50780 5078990c59bd83a8ea13053e74a9da5f 598 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 480 498 - T 12-10-2018 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 VAPA_1c50780 5078990c59bd83a8ea13053e74a9da5f 598 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 320 339 6.6E-21 T 12-10-2018 VAPA_1c50780 5078990c59bd83a8ea13053e74a9da5f 598 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 480 495 6.6E-21 T 12-10-2018 VAPA_1c50780 5078990c59bd83a8ea13053e74a9da5f 598 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 497 512 6.6E-21 T 12-10-2018 VAPA_1c50780 5078990c59bd83a8ea13053e74a9da5f 598 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 533 545 6.6E-21 T 12-10-2018 VAPA_1c50780 5078990c59bd83a8ea13053e74a9da5f 598 SUPERFAMILY SSF52009 172 270 4.19E-30 T 12-10-2018 IPR036637 Phosphohistidine domain superfamily GO:0016310|GO:0016772 VAPA_1c50780 5078990c59bd83a8ea13053e74a9da5f 598 Pfam PF00391 PEP-utilising enzyme, mobile domain 181 252 3.6E-24 T 12-10-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 VAPA_1c50780 5078990c59bd83a8ea13053e74a9da5f 598 TIGRFAM TIGR01417 PTS_I_fam: phosphoenolpyruvate-protein phosphotransferase 179 590 1.2E-125 T 12-10-2018 IPR006318 Phosphotransferase system, enzyme I-like GO:0016772 VAPA_1c50780 5078990c59bd83a8ea13053e74a9da5f 598 Gene3D G3DSA:3.20.20.60 261 597 1.0E-106 T 12-10-2018 VAPA_1c05300 97cfe8677fa4d256ed1617ce7b22beb4 724 Gene3D G3DSA:1.20.1220.12 585 724 2.3E-71 T 12-10-2018 VAPA_1c05300 97cfe8677fa4d256ed1617ce7b22beb4 724 Pfam PF01274 Malate synthase 18 698 5.3E-168 T 12-10-2018 IPR001465 Malate synthase GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 VAPA_1c05300 97cfe8677fa4d256ed1617ce7b22beb4 724 TIGRFAM TIGR01345 malate_syn_G: malate synthase G 5 722 0.0 T 12-10-2018 IPR006253 Malate synthase G GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 VAPA_1c05300 97cfe8677fa4d256ed1617ce7b22beb4 724 Gene3D G3DSA:3.20.20.360 10 582 1.6E-274 T 12-10-2018 VAPA_1c05300 97cfe8677fa4d256ed1617ce7b22beb4 724 SUPERFAMILY SSF51645 3 721 3.79E-298 T 12-10-2018 IPR011076 Malate synthase-like superfamily GO:0003824 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 VAPA_1c05300 97cfe8677fa4d256ed1617ce7b22beb4 724 Gene3D G3DSA:2.170.170.11 135 263 1.6E-274 T 12-10-2018 IPR023310 Malate synthase G, beta sub-domain GO:0004474 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 VAPA_1c05300 97cfe8677fa4d256ed1617ce7b22beb4 724 Hamap MF_00641 Malate synthase G [glcB]. 1 724 398.581 T 12-10-2018 IPR006253 Malate synthase G GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 VAPA_1c22170 d2b784367d8b44c0022655a0381ffcc7 507 SUPERFAMILY SSF53474 72 454 2.03E-13 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c22170 d2b784367d8b44c0022655a0381ffcc7 507 Pfam PF07519 Tannase and feruloyl esterase 54 505 1.6E-100 T 12-10-2018 IPR011118 Tannase/feruloyl esterase MetaCyc: PWY-6784 VAPA_1c29480 a8eb8f0df729af9d30ba59f15dcfa67a 281 Pfam PF01148 Cytidylyltransferase family 3 278 2.0E-48 T 12-10-2018 VAPA_1c29480 a8eb8f0df729af9d30ba59f15dcfa67a 281 ProSitePatterns PS01315 Phosphatidate cytidylyltransferase signature. 240 266 - T 12-10-2018 IPR000374 Phosphatidate cytidylyltransferase GO:0016020|GO:0016772 KEGG: 00564+2.7.7.41|KEGG: 04070+2.7.7.41|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7817 VAPA_1c46410 114a03da4a92e9f818158bc3bfdfbeb2 202 Pfam PF00775 Dioxygenase 46 120 2.0E-11 T 12-10-2018 IPR000627 Intradiol ring-cleavage dioxygenase, C-terminal GO:0003824|GO:0006725|GO:0008199|GO:0055114 VAPA_1c46410 114a03da4a92e9f818158bc3bfdfbeb2 202 ProSitePatterns PS00083 Intradiol ring-cleavage dioxygenases signature. 55 83 - T 12-10-2018 IPR000627 Intradiol ring-cleavage dioxygenase, C-terminal GO:0003824|GO:0006725|GO:0008199|GO:0055114 VAPA_1c46410 114a03da4a92e9f818158bc3bfdfbeb2 202 Gene3D G3DSA:2.60.130.10 4 202 2.3E-62 T 12-10-2018 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 VAPA_1c46410 114a03da4a92e9f818158bc3bfdfbeb2 202 SUPERFAMILY SSF49482 10 202 1.83E-48 T 12-10-2018 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 VAPA_1c46410 114a03da4a92e9f818158bc3bfdfbeb2 202 TIGRFAM TIGR02423 protocat_alph: protocatechuate 3,4-dioxygenase, alpha subunit 13 202 2.0E-69 T 12-10-2018 IPR012786 Protocatechuate 3,4-dioxygenase, alpha subunit GO:0005506|GO:0018578|GO:0019439|GO:0055114 KEGG: 00362+1.13.11.3|KEGG: 00624+1.13.11.3|MetaCyc: PWY-6041 VAPA_1c07090 ac89594d8be524065e7ca8351fc43da2 113 Pfam PF13586 Transposase DDE domain 27 106 2.7E-9 T 12-10-2018 IPR025668 Transposase DDE domain VAPA_1c47260 ac7a8c5ad655da2d1a5c3c7d379d2f37 90 SMART SM00530 16 71 4.0E-6 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 VAPA_1c47260 ac7a8c5ad655da2d1a5c3c7d379d2f37 90 Gene3D G3DSA:1.10.260.40 4 83 2.5E-14 T 12-10-2018 VAPA_1c47260 ac7a8c5ad655da2d1a5c3c7d379d2f37 90 SUPERFAMILY SSF47413 10 73 4.29E-13 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 VAPA_1c47260 ac7a8c5ad655da2d1a5c3c7d379d2f37 90 Pfam PF13560 Helix-turn-helix domain 12 71 3.5E-9 T 12-10-2018 VAPA_1c03660 a4e17ff182decad226efea8f29948d18 542 SUPERFAMILY SSF54373 298 481 4.12E-60 T 12-10-2018 VAPA_1c03660 a4e17ff182decad226efea8f29948d18 542 Gene3D G3DSA:3.50.50.60 6 537 6.5E-168 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c03660 a4e17ff182decad226efea8f29948d18 542 ProSitePatterns PS00624 GMC oxidoreductases signature 2. 262 276 - T 12-10-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 VAPA_1c03660 a4e17ff182decad226efea8f29948d18 542 Gene3D G3DSA:3.30.560.10 44 476 6.5E-168 T 12-10-2018 VAPA_1c03660 a4e17ff182decad226efea8f29948d18 542 PIRSF PIRSF000137 1 542 1.1E-141 T 12-10-2018 IPR012132 Glucose-methanol-choline oxidoreductase GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 VAPA_1c03660 a4e17ff182decad226efea8f29948d18 542 Pfam PF05199 GMC oxidoreductase 395 533 4.2E-36 T 12-10-2018 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 VAPA_1c03660 a4e17ff182decad226efea8f29948d18 542 SUPERFAMILY SSF51905 3 540 6.85E-79 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c03660 a4e17ff182decad226efea8f29948d18 542 Pfam PF00732 GMC oxidoreductase 6 303 2.4E-75 T 12-10-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 VAPA_1c36450 d1305c9b5e8bd91854be1b15dab60fee 422 Gene3D G3DSA:3.40.190.10 170 338 3.7E-25 T 12-10-2018 VAPA_1c36450 d1305c9b5e8bd91854be1b15dab60fee 422 Gene3D G3DSA:3.40.190.10 38 169 3.3E-8 T 12-10-2018 VAPA_1c36450 d1305c9b5e8bd91854be1b15dab60fee 422 SUPERFAMILY SSF53850 40 420 3.03E-50 T 12-10-2018 VAPA_1c36450 d1305c9b5e8bd91854be1b15dab60fee 422 Pfam PF13416 Bacterial extracellular solute-binding protein 52 353 3.2E-18 T 12-10-2018 IPR006059 Bacterial extracellular solute-binding protein VAPA_1c13470 c04cb27671a2aa35180d12e33c0d6f03 404 Pfam PF00487 Fatty acid desaturase 25 228 1.5E-17 T 12-10-2018 IPR005804 Fatty acid desaturase domain GO:0006629 VAPA_1c13470 c04cb27671a2aa35180d12e33c0d6f03 404 Pfam PF01610 Transposase 281 401 1.6E-6 T 12-10-2018 IPR002560 Transposase IS204/IS1001/IS1096/IS1165, DDE domain VAPA_1c47010 62d565b579482c3d473098062641f614 173 Pfam PF13671 AAA domain 19 161 1.5E-28 T 12-10-2018 VAPA_1c47010 62d565b579482c3d473098062641f614 173 SUPERFAMILY SSF52540 17 139 8.27E-20 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c47010 62d565b579482c3d473098062641f614 173 Gene3D G3DSA:3.40.50.300 2 172 7.3E-25 T 12-10-2018 VAPA_1c31850 ae1614823cabbfbc75757fee3fa5bd44 308 SUPERFAMILY SSF74653 216 298 6.41E-12 T 12-10-2018 VAPA_1c31850 ae1614823cabbfbc75757fee3fa5bd44 308 Pfam PF13103 TonB C terminal 220 295 2.6E-16 T 12-10-2018 VAPA_1c31850 ae1614823cabbfbc75757fee3fa5bd44 308 TIGRFAM TIGR02794 tolA_full: protein TolA 113 291 3.4E-19 T 12-10-2018 IPR014161 Tol-Pal system, TolA GO:0005215|GO:0016021|GO:0043213 VAPA_1c31850 ae1614823cabbfbc75757fee3fa5bd44 308 Gene3D G3DSA:3.30.1150.10 209 306 2.6E-8 T 12-10-2018 VAPA_1c01470 c319391478740c4bf2228fb39ac00dda 555 SMART SM00327 361 545 1.8E-11 T 12-10-2018 IPR002035 von Willebrand factor, type A VAPA_1c01470 c319391478740c4bf2228fb39ac00dda 555 Pfam PF00092 von Willebrand factor type A domain 364 524 8.2E-10 T 12-10-2018 IPR002035 von Willebrand factor, type A VAPA_1c01470 c319391478740c4bf2228fb39ac00dda 555 SUPERFAMILY SSF53300 361 547 2.23E-19 T 12-10-2018 IPR036465 von Willebrand factor A-like domain superfamily VAPA_1c01470 c319391478740c4bf2228fb39ac00dda 555 Gene3D G3DSA:3.40.50.410 360 549 8.0E-18 T 12-10-2018 IPR036465 von Willebrand factor A-like domain superfamily VAPA_1c51320 67a9f9501438c298373a3b9452c6e8d7 371 Gene3D G3DSA:3.40.190.170 36 341 5.1E-108 T 12-10-2018 IPR038404 TRAP transporter solute receptor DctP superfamily VAPA_1c51320 67a9f9501438c298373a3b9452c6e8d7 371 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 39 312 3.3E-37 T 12-10-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0030288|GO:0055085 VAPA_1c51320 67a9f9501438c298373a3b9452c6e8d7 371 PIRSF PIRSF039026 7 362 2.4E-129 T 12-10-2018 IPR026289 Solute binding protein, mannitol/chloroaromatic system-like VAPA_1c51320 67a9f9501438c298373a3b9452c6e8d7 371 Gene3D G3DSA:3.40.190.10 157 328 5.1E-108 T 12-10-2018 VAPA_1c01950 22f8f34c72880e4dd64382d7b7f237e0 323 Gene3D G3DSA:3.40.190.150 28 313 9.6E-108 T 12-10-2018 VAPA_1c01950 22f8f34c72880e4dd64382d7b7f237e0 323 PIRSF PIRSF017082 1 322 1.7E-75 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c01950 22f8f34c72880e4dd64382d7b7f237e0 323 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 47 320 1.0E-88 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c01950 22f8f34c72880e4dd64382d7b7f237e0 323 SUPERFAMILY SSF53850 116 284 2.71E-9 T 12-10-2018 VAPA_1c01950 22f8f34c72880e4dd64382d7b7f237e0 323 Gene3D G3DSA:3.40.190.10 125 248 9.6E-108 T 12-10-2018 VAPA_1c06210 ef176de46fff8545827e75fe6522e50b 279 SMART SM00331 4 243 4.9E-21 T 12-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 VAPA_1c06210 ef176de46fff8545827e75fe6522e50b 279 Gene3D G3DSA:3.60.40.10 1 243 1.6E-47 T 12-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 VAPA_1c06210 ef176de46fff8545827e75fe6522e50b 279 Pfam PF13672 Protein phosphatase 2C 11 211 4.4E-11 T 12-10-2018 VAPA_1c06210 ef176de46fff8545827e75fe6522e50b 279 SUPERFAMILY SSF81606 3 242 1.44E-47 T 12-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 VAPA_1c06210 ef176de46fff8545827e75fe6522e50b 279 SMART SM00332 1 241 3.3E-6 T 12-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 VAPA_1c19280 20cbca9f0e714e33b05b9ddd93c2f44f 396 Gene3D G3DSA:3.40.50.2300 156 293 1.3E-73 T 12-10-2018 VAPA_1c19280 20cbca9f0e714e33b05b9ddd93c2f44f 396 Pfam PF13458 Periplasmic binding protein 38 369 1.2E-62 T 12-10-2018 IPR028081 Leucine-binding protein domain VAPA_1c19280 20cbca9f0e714e33b05b9ddd93c2f44f 396 SUPERFAMILY SSF53822 36 379 2.93E-65 T 12-10-2018 IPR028082 Periplasmic binding protein-like I VAPA_1c19280 20cbca9f0e714e33b05b9ddd93c2f44f 396 Gene3D G3DSA:3.40.50.2300 46 355 1.3E-73 T 12-10-2018 VAPA_2c11500 9be015636bfd008d426831500dc97b9f 386 SMART SM00897 31 233 1.1E-50 T 12-10-2018 IPR013702 FIST domain, N-terminal VAPA_2c11500 9be015636bfd008d426831500dc97b9f 386 SMART SM01204 234 364 2.3E-34 T 12-10-2018 IPR019494 FIST, C-domain Reactome: R-HSA-8951664|Reactome: R-HSA-983168 VAPA_2c11500 9be015636bfd008d426831500dc97b9f 386 Pfam PF08495 FIST N domain 35 231 3.9E-34 T 12-10-2018 IPR013702 FIST domain, N-terminal VAPA_2c11500 9be015636bfd008d426831500dc97b9f 386 Pfam PF10442 FIST C domain 234 362 2.9E-16 T 12-10-2018 IPR019494 FIST, C-domain Reactome: R-HSA-8951664|Reactome: R-HSA-983168 VAPA_1c25890 63e005b132c2a7289c7c4631a95aeedc 213 PIRSF PIRSF000239 1 210 1.9E-75 T 12-10-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 VAPA_1c25890 63e005b132c2a7289c7c4631a95aeedc 213 Pfam PF10417 C-terminal domain of 1-Cys peroxiredoxin 157 183 5.1E-10 T 12-10-2018 IPR019479 Peroxiredoxin, C-terminal GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 VAPA_1c25890 63e005b132c2a7289c7c4631a95aeedc 213 SUPERFAMILY SSF52833 4 210 1.93E-65 T 12-10-2018 IPR036249 Thioredoxin-like superfamily VAPA_1c25890 63e005b132c2a7289c7c4631a95aeedc 213 Gene3D G3DSA:3.30.1020.10 147 211 6.5E-27 T 12-10-2018 VAPA_1c25890 63e005b132c2a7289c7c4631a95aeedc 213 Pfam PF00578 AhpC/TSA family 7 136 1.2E-28 T 12-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 VAPA_1c25890 63e005b132c2a7289c7c4631a95aeedc 213 Gene3D G3DSA:3.40.30.10 2 146 7.3E-47 T 12-10-2018 VAPA_1c18550 9104211f6fdc571113dd7435ee00b8f7 147 Gene3D G3DSA:3.10.129.10 4 146 1.7E-47 T 12-10-2018 VAPA_1c18550 9104211f6fdc571113dd7435ee00b8f7 147 Pfam PF03061 Thioesterase superfamily 31 112 1.4E-14 T 12-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 VAPA_1c18550 9104211f6fdc571113dd7435ee00b8f7 147 SUPERFAMILY SSF54637 12 141 9.25E-37 T 12-10-2018 IPR029069 HotDog domain superfamily VAPA_1c01440 ed3e1a56e97ad8db817d911d2930205e 296 Gene3D G3DSA:3.40.190.290 95 294 1.0E-33 T 12-10-2018 VAPA_1c01440 ed3e1a56e97ad8db817d911d2930205e 296 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 64 1.9E-21 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c01440 ed3e1a56e97ad8db817d911d2930205e 296 Pfam PF03466 LysR substrate binding domain 90 290 4.0E-33 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_1c01440 ed3e1a56e97ad8db817d911d2930205e 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 32 42 4.5E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c01440 ed3e1a56e97ad8db817d911d2930205e 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 53 4.5E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c01440 ed3e1a56e97ad8db817d911d2930205e 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 21 32 4.5E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c01440 ed3e1a56e97ad8db817d911d2930205e 296 SUPERFAMILY SSF53850 91 292 1.22E-32 T 12-10-2018 VAPA_1c01440 ed3e1a56e97ad8db817d911d2930205e 296 Gene3D G3DSA:1.10.10.10 4 94 5.0E-25 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c01440 ed3e1a56e97ad8db817d911d2930205e 296 SUPERFAMILY SSF46785 4 113 3.47E-25 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c02750 22e5478967f14f21824f8af779c872dd 274 Pfam PF09694 Bacterial protein of unknown function (Gcw_chp) 24 239 1.1E-38 T 12-10-2018 IPR010239 Conserved hypothetical protein CHP02001 VAPA_1c02750 22e5478967f14f21824f8af779c872dd 274 TIGRFAM TIGR02001 gcw_chp: conserved hypothetical protein 9 234 2.7E-33 T 12-10-2018 IPR010239 Conserved hypothetical protein CHP02001 VAPA_2c06900 b5d0f930dce509b52a261ef8f1d68478 150 SUPERFAMILY SSF102546 1 146 7.72E-44 T 12-10-2018 IPR023750 RbsD-like superfamily GO:0005996|GO:0016853|GO:0048029 Reactome: R-HSA-6787639 VAPA_2c06900 b5d0f930dce509b52a261ef8f1d68478 150 Pfam PF05025 RbsD / FucU transport protein family 3 145 4.9E-36 T 12-10-2018 IPR007721 D-ribose pyranase RbsD/L-fucose mutarotase FucU GO:0005996|GO:0016853|GO:0048029 Reactome: R-HSA-6787639 VAPA_2c06900 b5d0f930dce509b52a261ef8f1d68478 150 Gene3D G3DSA:3.40.1650.10 1 149 4.5E-54 T 12-10-2018 IPR023750 RbsD-like superfamily GO:0005996|GO:0016853|GO:0048029 Reactome: R-HSA-6787639 VAPA_1c01220 1764e163a8550de2a2a7b30b9c52f87f 277 Gene3D G3DSA:3.30.450.40 102 276 1.6E-54 T 12-10-2018 IPR029016 GAF-like domain superfamily VAPA_1c01220 1764e163a8550de2a2a7b30b9c52f87f 277 SUPERFAMILY SSF46785 28 100 6.95E-17 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c01220 1764e163a8550de2a2a7b30b9c52f87f 277 SUPERFAMILY SSF55781 93 274 1.5E-45 T 12-10-2018 VAPA_1c01220 1764e163a8550de2a2a7b30b9c52f87f 277 Gene3D G3DSA:1.10.10.10 26 101 3.9E-20 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c01220 1764e163a8550de2a2a7b30b9c52f87f 277 Pfam PF01614 Bacterial transcriptional regulator 151 270 4.2E-34 T 12-10-2018 IPR014757 Transcription regulator IclR, C-terminal VAPA_1c01220 1764e163a8550de2a2a7b30b9c52f87f 277 SMART SM00346 28 118 4.5E-24 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 VAPA_1c01220 1764e163a8550de2a2a7b30b9c52f87f 277 Pfam PF09339 IclR helix-turn-helix domain 30 80 2.2E-16 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 VAPA_1c27310 60a42790ffcd503390db3de651d804fd 485 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 280 291 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site VAPA_1c27310 60a42790ffcd503390db3de651d804fd 485 Gene3D G3DSA:3.30.70.20 223 299 2.4E-5 T 12-10-2018 VAPA_1c27310 60a42790ffcd503390db3de651d804fd 485 Gene3D G3DSA:2.60.40.10 369 484 6.8E-26 T 12-10-2018 IPR013783 Immunoglobulin-like fold VAPA_1c27310 60a42790ffcd503390db3de651d804fd 485 Pfam PF13746 4Fe-4S dicluster domain 227 332 7.1E-42 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain VAPA_1c27310 60a42790ffcd503390db3de651d804fd 485 Pfam PF11614 IG-like fold at C-terminal of FixG, putative oxidoreductase 368 484 2.4E-29 T 12-10-2018 IPR032879 FixG, C-terminal immunoglobulin-like domain VAPA_1c27310 60a42790ffcd503390db3de651d804fd 485 Pfam PF12801 4Fe-4S binding domain 105 144 2.9E-11 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain VAPA_1c27310 60a42790ffcd503390db3de651d804fd 485 SUPERFAMILY SSF54862 113 378 1.05E-33 T 12-10-2018 VAPA_1c27310 60a42790ffcd503390db3de651d804fd 485 TIGRFAM TIGR02745 ccoG_rdxA_fixG: cytochrome c oxidase accessory protein CcoG 49 482 1.1E-152 T 12-10-2018 IPR014116 Cytochrome c oxidase cbb3 type, accessory protein FixG GO:0016021|GO:0055114 VAPA_1c26970 2ef8b3c4af590a677dd20f63d16765b2 219 Hamap MF_00165 Thymidylate kinase [tmk]. 5 209 27.712 T 12-10-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 VAPA_1c26970 2ef8b3c4af590a677dd20f63d16765b2 219 SUPERFAMILY SSF52540 1 203 1.21E-41 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c26970 2ef8b3c4af590a677dd20f63d16765b2 219 TIGRFAM TIGR00041 DTMP_kinase: dTMP kinase 1 200 2.3E-44 T 12-10-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 VAPA_1c26970 2ef8b3c4af590a677dd20f63d16765b2 219 Gene3D G3DSA:3.40.50.300 2 208 2.1E-58 T 12-10-2018 VAPA_1c26970 2ef8b3c4af590a677dd20f63d16765b2 219 Pfam PF02223 Thymidylate kinase 9 200 1.5E-42 T 12-10-2018 IPR039430 Thymidylate kinase-like domain KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210 VAPA_1c43660 bdc119e7dab13f4c86413c416fb3cc79 171 Gene3D G3DSA:2.60.120.10 24 155 4.4E-19 T 12-10-2018 IPR014710 RmlC-like jelly roll fold VAPA_1c43660 bdc119e7dab13f4c86413c416fb3cc79 171 SUPERFAMILY SSF51182 19 165 4.78E-25 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily VAPA_1c43660 bdc119e7dab13f4c86413c416fb3cc79 171 Pfam PF07883 Cupin domain 65 131 1.6E-10 T 12-10-2018 IPR013096 Cupin 2, conserved barrel VAPA_1c37740 aeda546712c7aed045526f8285069323 147 SUPERFAMILY SSF52402 1 145 6.78E-38 T 12-10-2018 VAPA_1c37740 aeda546712c7aed045526f8285069323 147 Pfam PF00582 Universal stress protein family 1 144 3.0E-34 T 12-10-2018 IPR006016 UspA VAPA_1c37740 aeda546712c7aed045526f8285069323 147 PIRSF PIRSF006276 1 146 3.9E-20 T 12-10-2018 IPR006015 Universal stress protein A VAPA_1c37740 aeda546712c7aed045526f8285069323 147 PRINTS PR01438 Universal stress protein signature 122 144 1.1E-21 T 12-10-2018 IPR006015 Universal stress protein A VAPA_1c37740 aeda546712c7aed045526f8285069323 147 PRINTS PR01438 Universal stress protein signature 2 20 1.1E-21 T 12-10-2018 IPR006015 Universal stress protein A VAPA_1c37740 aeda546712c7aed045526f8285069323 147 PRINTS PR01438 Universal stress protein signature 104 116 1.1E-21 T 12-10-2018 IPR006015 Universal stress protein A VAPA_1c37740 aeda546712c7aed045526f8285069323 147 Gene3D G3DSA:3.40.50.620 1 144 6.0E-39 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold VAPA_1c40670 69d1d7c2c828525b89c65d4066ac21db 156 SUPERFAMILY SSF82199 9 147 2.88E-32 T 12-10-2018 VAPA_1c40670 69d1d7c2c828525b89c65d4066ac21db 156 SMART SM00508 134 150 1.0E-4 T 12-10-2018 IPR003616 Post-SET domain KEGG: 00310+2.1.1.43|Reactome: R-HSA-3214841 VAPA_1c40670 69d1d7c2c828525b89c65d4066ac21db 156 Pfam PF00856 SET domain 22 123 1.6E-8 T 12-10-2018 IPR001214 SET domain GO:0005515 VAPA_1c40670 69d1d7c2c828525b89c65d4066ac21db 156 Gene3D G3DSA:2.170.270.10 3 153 3.3E-35 T 12-10-2018 VAPA_1c40670 69d1d7c2c828525b89c65d4066ac21db 156 SMART SM00317 11 130 2.9E-14 T 12-10-2018 IPR001214 SET domain GO:0005515 VAPA_2c00820 1212effe3b1ea50c1c9b45d6b8f23931 114 Gene3D G3DSA:3.90.930.1 9 104 9.8E-14 T 12-10-2018 VAPA_2c00820 1212effe3b1ea50c1c9b45d6b8f23931 114 Pfam PF07661 MORN repeat variant 61 80 2.8E-4 T 12-10-2018 IPR011652 MORN variant VAPA_2c00820 1212effe3b1ea50c1c9b45d6b8f23931 114 Pfam PF07661 MORN repeat variant 36 55 0.017 T 12-10-2018 IPR011652 MORN variant VAPA_2c00820 1212effe3b1ea50c1c9b45d6b8f23931 114 SUPERFAMILY SSF82185 34 96 1.31E-14 T 12-10-2018 VAPA_1c42560 c5fe1bd3ddca2b4bd5df3369fb825683 86 ProSitePatterns PS00195 Glutaredoxin active site. 6 22 - T 12-10-2018 IPR011767 Glutaredoxin active site GO:0009055|GO:0045454 Reactome: R-HSA-499943 VAPA_1c42560 c5fe1bd3ddca2b4bd5df3369fb825683 86 Gene3D G3DSA:3.40.30.10 1 85 1.5E-27 T 12-10-2018 VAPA_1c42560 c5fe1bd3ddca2b4bd5df3369fb825683 86 SUPERFAMILY SSF52833 2 85 8.39E-29 T 12-10-2018 IPR036249 Thioredoxin-like superfamily VAPA_1c42560 c5fe1bd3ddca2b4bd5df3369fb825683 86 PRINTS PR00160 Glutaredoxin signature 4 22 5.7E-17 T 12-10-2018 IPR014025 Glutaredoxin subgroup VAPA_1c42560 c5fe1bd3ddca2b4bd5df3369fb825683 86 PRINTS PR00160 Glutaredoxin signature 47 60 5.7E-17 T 12-10-2018 IPR014025 Glutaredoxin subgroup VAPA_1c42560 c5fe1bd3ddca2b4bd5df3369fb825683 86 PRINTS PR00160 Glutaredoxin signature 61 74 5.7E-17 T 12-10-2018 IPR014025 Glutaredoxin subgroup VAPA_1c42560 c5fe1bd3ddca2b4bd5df3369fb825683 86 TIGRFAM TIGR02181 GRX_bact: glutaredoxin 3 4 83 2.3E-34 T 12-10-2018 IPR011900 Glutaredoxin, GrxC GO:0045454 VAPA_1c42560 c5fe1bd3ddca2b4bd5df3369fb825683 86 Pfam PF00462 Glutaredoxin 4 64 9.1E-22 T 12-10-2018 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 VAPA_1c29740 8159c26c52a62c92aa477e1a4cca23d7 164 TIGRFAM TIGR00151 ispF: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 8 161 2.2E-63 T 12-10-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 VAPA_1c29740 8159c26c52a62c92aa477e1a4cca23d7 164 ProSitePatterns PS01350 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase signature. 41 56 - T 12-10-2018 IPR020555 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, conserved site GO:0008685 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 VAPA_1c29740 8159c26c52a62c92aa477e1a4cca23d7 164 Hamap MF_00107 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase [ispF]. 7 162 35.223 T 12-10-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 VAPA_1c29740 8159c26c52a62c92aa477e1a4cca23d7 164 SUPERFAMILY SSF69765 6 162 3.01E-63 T 12-10-2018 IPR036571 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase superfamily GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 VAPA_1c29740 8159c26c52a62c92aa477e1a4cca23d7 164 Gene3D G3DSA:3.30.1330.50 5 164 6.8E-67 T 12-10-2018 IPR036571 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase superfamily GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 VAPA_1c29740 8159c26c52a62c92aa477e1a4cca23d7 164 Pfam PF02542 YgbB family 7 160 1.9E-63 T 12-10-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 VAPA_1c10280 b5135daa81e56ae34d5cf5d1985dcd1e 310 SUPERFAMILY SSF52402 39 266 6.48E-53 T 12-10-2018 VAPA_1c10280 b5135daa81e56ae34d5cf5d1985dcd1e 310 Pfam PF01171 PP-loop family 52 215 1.3E-14 T 12-10-2018 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 VAPA_1c10280 b5135daa81e56ae34d5cf5d1985dcd1e 310 PIRSF PIRSF004976 9 284 1.5E-72 T 12-10-2018 IPR035107 tRNA thiolation protein, TtcA/Ctu1 type GO:0008033 Reactome: R-HSA-6782315 VAPA_1c10280 b5135daa81e56ae34d5cf5d1985dcd1e 310 Hamap MF_01850 tRNA-cytidine(32) 2-sulfurtransferase [ttcA]. 21 282 56.607 T 12-10-2018 IPR012089 tRNA-cytidine(32) 2-sulfurtransferase GO:0008033 VAPA_1c10280 b5135daa81e56ae34d5cf5d1985dcd1e 310 Gene3D G3DSA:3.40.50.620 19 271 2.6E-44 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold VAPA_1c33860 8a137c3fd3b8e55290462cb160b8cd29 262 Gene3D G3DSA:1.10.30.40 2 54 1.2E-8 T 12-10-2018 VAPA_1c33860 8a137c3fd3b8e55290462cb160b8cd29 262 Gene3D G3DSA:3.40.50.11240 64 242 9.3E-62 T 12-10-2018 VAPA_1c33860 8a137c3fd3b8e55290462cb160b8cd29 262 Pfam PF05985 Ethanolamine ammonia-lyase light chain (EutC) 10 243 7.6E-88 T 12-10-2018 IPR009246 Ethanolamine ammonia-lyase light chain GO:0006520|GO:0008851 KEGG: 00564+4.3.1.7 VAPA_1c33860 8a137c3fd3b8e55290462cb160b8cd29 262 PIRSF PIRSF018982 1 253 1.3E-90 T 12-10-2018 IPR009246 Ethanolamine ammonia-lyase light chain GO:0006520|GO:0008851 KEGG: 00564+4.3.1.7 VAPA_2c05170 cdc5abcafa9f81fc305fd52a7ce924b5 337 Pfam PF04952 Succinylglutamate desuccinylase / Aspartoacylase family 44 327 1.4E-37 T 12-10-2018 IPR007036 Succinylglutamate desuccinylase/aspartoacylase GO:0016788 VAPA_2c05170 cdc5abcafa9f81fc305fd52a7ce924b5 337 Gene3D G3DSA:3.40.630.10 10 329 1.0E-77 T 12-10-2018 VAPA_2c05170 cdc5abcafa9f81fc305fd52a7ce924b5 337 SUPERFAMILY SSF53187 41 330 1.06E-34 T 12-10-2018 VAPA_2c05170 cdc5abcafa9f81fc305fd52a7ce924b5 337 PIRSF PIRSF039012 9 335 2.7E-66 T 12-10-2018 IPR007036 Succinylglutamate desuccinylase/aspartoacylase GO:0016788 VAPA_2c05200 e02042e94e24f424f0c8b1bb5b5c15cc 381 SUPERFAMILY SSF51604 128 376 1.97E-64 T 12-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily VAPA_2c05200 e02042e94e24f424f0c8b1bb5b5c15cc 381 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 14 140 1.3E-16 T 12-10-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain VAPA_2c05200 e02042e94e24f424f0c8b1bb5b5c15cc 381 Pfam PF13378 Enolase C-terminal domain-like 161 372 5.5E-56 T 12-10-2018 IPR029065 Enolase C-terminal domain-like VAPA_2c05200 e02042e94e24f424f0c8b1bb5b5c15cc 381 ProSitePatterns PS00909 Mandelate racemase / muconate lactonizing enzyme family signature 2. 201 232 - T 12-10-2018 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 VAPA_2c05200 e02042e94e24f424f0c8b1bb5b5c15cc 381 SMART SM00922 155 252 3.3E-25 T 12-10-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal VAPA_2c05200 e02042e94e24f424f0c8b1bb5b5c15cc 381 Gene3D G3DSA:3.30.390.10 36 369 1.5E-126 T 12-10-2018 IPR029017 Enolase-like, N-terminal VAPA_2c05200 e02042e94e24f424f0c8b1bb5b5c15cc 381 SUPERFAMILY SSF54826 13 141 3.54E-26 T 12-10-2018 VAPA_2c05200 e02042e94e24f424f0c8b1bb5b5c15cc 381 Gene3D G3DSA:3.20.20.120 133 367 1.5E-126 T 12-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily VAPA_1c12890 d1d9938aa66345dd8f752dae96741e64 194 SUPERFAMILY SSF48317 3 163 8.5E-24 T 12-10-2018 IPR036938 Phosphatidic acid phosphatase type 2/haloperoxidase superfamily VAPA_1c12890 d1d9938aa66345dd8f752dae96741e64 194 Gene3D G3DSA:1.20.144.10 85 191 7.5E-17 T 12-10-2018 VAPA_1c12890 d1d9938aa66345dd8f752dae96741e64 194 Pfam PF01569 PAP2 superfamily 56 163 2.0E-15 T 12-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase VAPA_1c12890 d1d9938aa66345dd8f752dae96741e64 194 SMART SM00014 53 164 1.6E-13 T 12-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase VAPA_1c31650 c8f165ca1119500c9145b18748546b2a 972 Pfam PF03993 Domain of Unknown Function (DUF349) 416 492 3.0E-11 T 12-10-2018 IPR007139 Protein of unknown function DUF349 VAPA_1c52000 af84e7966acd0ce613743196faa6e8be 270 SUPERFAMILY SSF52540 7 246 4.49E-49 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c52000 af84e7966acd0ce613743196faa6e8be 270 Pfam PF00005 ABC transporter 24 175 1.2E-21 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c52000 af84e7966acd0ce613743196faa6e8be 270 SMART SM00382 33 227 4.4E-6 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c52000 af84e7966acd0ce613743196faa6e8be 270 Gene3D G3DSA:3.40.50.300 4 249 1.7E-51 T 12-10-2018 VAPA_1c24650 bc1db8c862ccee7bb50a4ea85315d386 1087 SUPERFAMILY SSF52540 24 878 1.16E-89 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c24650 bc1db8c862ccee7bb50a4ea85315d386 1087 Pfam PF00580 UvrD/REP helicase N-terminal domain 25 460 9.0E-42 T 12-10-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 VAPA_1c24650 bc1db8c862ccee7bb50a4ea85315d386 1087 Pfam PF12705 PD-(D/E)XK nuclease superfamily 939 1068 8.2E-6 T 12-10-2018 IPR038726 PD-(D/E)XK endonuclease-like domain, AddAB-type VAPA_1c24650 bc1db8c862ccee7bb50a4ea85315d386 1087 Gene3D G3DSA:3.40.50.300 560 655 3.5E-19 T 12-10-2018 VAPA_1c24650 bc1db8c862ccee7bb50a4ea85315d386 1087 Gene3D G3DSA:3.40.50.300 347 492 1.6E-26 T 12-10-2018 VAPA_1c24650 bc1db8c862ccee7bb50a4ea85315d386 1087 Pfam PF13361 UvrD-like helicase C-terminal domain 564 659 1.5E-8 T 12-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 VAPA_1c24650 bc1db8c862ccee7bb50a4ea85315d386 1087 Gene3D G3DSA:3.40.50.300 754 897 2.0E-16 T 12-10-2018 VAPA_1c24650 bc1db8c862ccee7bb50a4ea85315d386 1087 Pfam PF13361 UvrD-like helicase C-terminal domain 776 872 2.7E-10 T 12-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 VAPA_1c47020 6d83b87a9b9971a2162cf7028882bf0e 219 Gene3D G3DSA:1.10.357.10 7 211 2.9E-53 T 12-10-2018 VAPA_1c47020 6d83b87a9b9971a2162cf7028882bf0e 219 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 26 39 6.7E-5 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 VAPA_1c47020 6d83b87a9b9971a2162cf7028882bf0e 219 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 47 70 6.7E-5 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 VAPA_1c47020 6d83b87a9b9971a2162cf7028882bf0e 219 SUPERFAMILY SSF46689 17 84 8.98E-13 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 VAPA_1c47020 6d83b87a9b9971a2162cf7028882bf0e 219 Pfam PF00440 Bacterial regulatory proteins, tetR family 28 70 3.1E-10 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 VAPA_1c24230 8aef510d8ffa049bbb6aed463042bc44 279 Gene3D G3DSA:3.60.130.10 1 279 4.2E-94 T 12-10-2018 VAPA_1c24230 8aef510d8ffa049bbb6aed463042bc44 279 Pfam PF02668 Taurine catabolism dioxygenase TauD, TfdA family 4 272 6.0E-71 T 12-10-2018 IPR003819 TauD/TfdA-like domain GO:0016491|GO:0055114 Reactome: R-HSA-71262 VAPA_1c24230 8aef510d8ffa049bbb6aed463042bc44 279 SUPERFAMILY SSF51197 2 279 4.3E-88 T 12-10-2018 VAPA_1c34980 8010b34c24283ca366f37f110154e861 318 Pfam PF04168 A predicted alpha-helical domain with a conserved ER motif. 1 314 1.5E-104 T 12-10-2018 IPR007296 Domain of unknown function DUF403 VAPA_1c27720 f827bd51b67050aa88d96934a3aa9b0e 291 SUPERFAMILY SSF81345 11 270 2.09E-23 T 12-10-2018 IPR037294 ABC transporter, BtuC-like VAPA_1c27720 f827bd51b67050aa88d96934a3aa9b0e 291 Pfam PF00950 ABC 3 transport family 14 272 1.1E-51 T 12-10-2018 IPR001626 ABC transporter, TroCD-like GO:0005887|GO:0042626|GO:0043190|GO:0055085 VAPA_1c31270 7444f21afa562925607f73a105579a1b 634 Gene3D G3DSA:3.20.10.10 493 619 2.9E-33 T 12-10-2018 VAPA_1c31270 7444f21afa562925607f73a105579a1b 634 SUPERFAMILY SSF56322 24 406 7.2E-94 T 12-10-2018 IPR005801 ADC synthase GO:0009058 VAPA_1c31270 7444f21afa562925607f73a105579a1b 634 Gene3D G3DSA:3.60.120.10 69 403 1.4E-99 T 12-10-2018 IPR005801 ADC synthase GO:0009058 VAPA_1c31270 7444f21afa562925607f73a105579a1b 634 Pfam PF01063 Amino-transferase class IV 414 616 5.8E-41 T 12-10-2018 IPR001544 Aminotransferase class IV GO:0003824 Reactome: R-HSA-70895 VAPA_1c31270 7444f21afa562925607f73a105579a1b 634 Gene3D G3DSA:3.30.470.10 404 485 2.9E-23 T 12-10-2018 VAPA_1c31270 7444f21afa562925607f73a105579a1b 634 SUPERFAMILY SSF56752 354 623 1.12E-52 T 12-10-2018 IPR036038 Aminotransferase-like, PLP-dependent enzymes GO:0003824 Reactome: R-HSA-70895 VAPA_1c31270 7444f21afa562925607f73a105579a1b 634 PRINTS PR00095 Anthranilate synthase component I signature 252 265 3.8E-9 T 12-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 VAPA_1c31270 7444f21afa562925607f73a105579a1b 634 PRINTS PR00095 Anthranilate synthase component I signature 332 346 3.8E-9 T 12-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 VAPA_1c31270 7444f21afa562925607f73a105579a1b 634 PRINTS PR00095 Anthranilate synthase component I signature 238 251 3.8E-9 T 12-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 VAPA_1c31270 7444f21afa562925607f73a105579a1b 634 Pfam PF00425 chorismate binding enzyme 128 401 1.1E-77 T 12-10-2018 IPR015890 Chorismate-utilising enzyme, C-terminal VAPA_1c25680 14edd8069d239f3b2b201bf96fcec1b7 315 SUPERFAMILY SSF52096 5 258 1.99E-59 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily VAPA_1c25680 14edd8069d239f3b2b201bf96fcec1b7 315 Pfam PF00378 Enoyl-CoA hydratase/isomerase 18 258 2.2E-36 T 12-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 VAPA_1c25680 14edd8069d239f3b2b201bf96fcec1b7 315 Gene3D G3DSA:3.90.226.10 3 308 1.6E-96 T 12-10-2018 VAPA_1c25680 14edd8069d239f3b2b201bf96fcec1b7 315 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 122 142 - T 12-10-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824 VAPA_1c28010 a85b9df56bc224cc5c9ae1346af0fa5b 158 TIGRFAM TIGR00086 smpB: SsrA-binding protein 12 154 9.6E-55 T 12-10-2018 IPR000037 SsrA-binding protein GO:0003723 VAPA_1c28010 a85b9df56bc224cc5c9ae1346af0fa5b 158 ProDom PD004488 SSRA-BINDING RNA-BINDING SMPB SMALL B TMRNA-BINDING SSRA 3D-STRUCTURE HOMOLOG BINDING 12 136 2.0E-63 T 12-10-2018 IPR000037 SsrA-binding protein GO:0003723 VAPA_1c28010 a85b9df56bc224cc5c9ae1346af0fa5b 158 SUPERFAMILY SSF74982 5 136 1.12E-49 T 12-10-2018 IPR023620 Small protein B VAPA_1c28010 a85b9df56bc224cc5c9ae1346af0fa5b 158 Pfam PF01668 SmpB protein 12 154 8.1E-59 T 12-10-2018 IPR000037 SsrA-binding protein GO:0003723 VAPA_1c28010 a85b9df56bc224cc5c9ae1346af0fa5b 158 Hamap MF_00023 SsrA-binding protein [smpB]. 1 158 71.26 T 12-10-2018 IPR000037 SsrA-binding protein GO:0003723 VAPA_1c28010 a85b9df56bc224cc5c9ae1346af0fa5b 158 Gene3D G3DSA:2.40.280.10 4 132 1.7E-47 T 12-10-2018 IPR023620 Small protein B VAPA_1c28010 a85b9df56bc224cc5c9ae1346af0fa5b 158 ProSitePatterns PS01317 SsrA-binding protein. 30 42 - T 12-10-2018 IPR020081 SsrA-binding protein, conserved site VAPA_1c34640 0f1325712b11aa18479ea6101a4ba984 568 SUPERFAMILY SSF52540 347 556 2.85E-46 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c34640 0f1325712b11aa18479ea6101a4ba984 568 Gene3D G3DSA:3.40.50.300 341 565 6.5E-55 T 12-10-2018 VAPA_1c34640 0f1325712b11aa18479ea6101a4ba984 568 Pfam PF00005 ABC transporter 367 513 2.8E-22 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c34640 0f1325712b11aa18479ea6101a4ba984 568 Gene3D G3DSA:1.20.1560.10 17 322 1.6E-29 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 VAPA_1c34640 0f1325712b11aa18479ea6101a4ba984 568 ProSitePatterns PS00211 ABC transporters family signature. 484 498 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_1c34640 0f1325712b11aa18479ea6101a4ba984 568 TIGRFAM TIGR02857 CydD: thiol reductant ABC exporter, CydD subunit 21 553 7.7E-149 T 12-10-2018 IPR014216 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydD GO:0005524|GO:0016020|GO:0042883 VAPA_1c34640 0f1325712b11aa18479ea6101a4ba984 568 SMART SM00382 375 559 3.4E-15 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c34640 0f1325712b11aa18479ea6101a4ba984 568 SUPERFAMILY SSF90123 25 320 3.79E-36 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 VAPA_1c34640 0f1325712b11aa18479ea6101a4ba984 568 Pfam PF00664 ABC transporter transmembrane region 138 267 5.3E-16 T 12-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 VAPA_2c11110 b0ecc6d1570e17a0df61540c65192fb3 289 SMART SM00450 161 281 5.6E-11 T 12-10-2018 IPR001763 Rhodanese-like domain VAPA_2c11110 b0ecc6d1570e17a0df61540c65192fb3 289 SMART SM00450 11 137 2.5E-19 T 12-10-2018 IPR001763 Rhodanese-like domain VAPA_2c11110 b0ecc6d1570e17a0df61540c65192fb3 289 Gene3D G3DSA:3.40.250.10 2 154 8.3E-47 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily VAPA_2c11110 b0ecc6d1570e17a0df61540c65192fb3 289 Gene3D G3DSA:3.40.250.10 157 288 3.5E-31 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily VAPA_2c11110 b0ecc6d1570e17a0df61540c65192fb3 289 SUPERFAMILY SSF52821 163 287 4.85E-31 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily VAPA_2c11110 b0ecc6d1570e17a0df61540c65192fb3 289 SUPERFAMILY SSF52821 2 147 2.75E-40 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily VAPA_2c11110 b0ecc6d1570e17a0df61540c65192fb3 289 ProSitePatterns PS00380 Rhodanese signature 1. 44 55 - T 12-10-2018 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350|MetaCyc: PWY-7927|Reactome: R-HSA-1614558 VAPA_2c11110 b0ecc6d1570e17a0df61540c65192fb3 289 ProSitePatterns PS00683 Rhodanese C-terminal signature. 265 275 - T 12-10-2018 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350|MetaCyc: PWY-7927|Reactome: R-HSA-1614558 VAPA_2c11110 b0ecc6d1570e17a0df61540c65192fb3 289 Pfam PF00581 Rhodanese-like domain 14 134 3.7E-18 T 12-10-2018 IPR001763 Rhodanese-like domain VAPA_2c11110 b0ecc6d1570e17a0df61540c65192fb3 289 Pfam PF00581 Rhodanese-like domain 164 277 7.8E-8 T 12-10-2018 IPR001763 Rhodanese-like domain VAPA_1c44900 3023c916dcc52a09bc52c9b756411553 419 Gene3D G3DSA:3.80.30.20 12 336 1.8E-96 T 12-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe VAPA_1c44900 3023c916dcc52a09bc52c9b756411553 419 TIGRFAM TIGR00539 hemN_rel: putative oxygen-independent coproporphyrinogen III oxidase 38 384 2.5E-104 T 12-10-2018 IPR004559 Oxygen-independent coproporphyrinogen III oxidase-like GO:0004109|GO:0005737|GO:0006779|GO:0055114 VAPA_1c44900 3023c916dcc52a09bc52c9b756411553 419 SMART SM00729 37 259 4.4E-51 T 12-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 VAPA_1c44900 3023c916dcc52a09bc52c9b756411553 419 Pfam PF06969 HemN C-terminal domain 344 405 3.4E-11 T 12-10-2018 IPR010723 HemN, C-terminal VAPA_1c44900 3023c916dcc52a09bc52c9b756411553 419 Pfam PF04055 Radical SAM superfamily 42 215 3.0E-19 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 VAPA_1c44900 3023c916dcc52a09bc52c9b756411553 419 SUPERFAMILY SSF102114 36 416 6.54E-102 T 12-10-2018 VAPA_1c35060 3cbe98889fc4697315ae89d9ecd18458 210 Pfam PF00072 Response regulator receiver domain 4 115 5.3E-30 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_1c35060 3cbe98889fc4697315ae89d9ecd18458 210 SUPERFAMILY SSF46894 141 209 1.16E-19 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 VAPA_1c35060 3cbe98889fc4697315ae89d9ecd18458 210 Pfam PF00196 Bacterial regulatory proteins, luxR family 148 203 3.8E-16 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_1c35060 3cbe98889fc4697315ae89d9ecd18458 210 Gene3D G3DSA:3.40.50.12740 2 209 2.2E-63 T 12-10-2018 VAPA_1c35060 3cbe98889fc4697315ae89d9ecd18458 210 SMART SM00421 146 203 4.7E-18 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_1c35060 3cbe98889fc4697315ae89d9ecd18458 210 SMART SM00448 2 115 8.7E-32 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_1c35060 3cbe98889fc4697315ae89d9ecd18458 210 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 163 179 2.6E-9 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_1c35060 3cbe98889fc4697315ae89d9ecd18458 210 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 179 191 2.6E-9 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_1c35060 3cbe98889fc4697315ae89d9ecd18458 210 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 149 163 2.6E-9 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_1c35060 3cbe98889fc4697315ae89d9ecd18458 210 SUPERFAMILY SSF52172 1 130 4.7E-35 T 12-10-2018 IPR011006 CheY-like superfamily VAPA_1c18120 66a60e6c625e50e18c996adeaf9d65f0 175 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 27 153 1.1E-26 T 12-10-2018 IPR007387 TRAP transporter, small membrane protein DctQ VAPA_1c51440 e8c10731f1e86e40d458b7f0512ee593 173 SUPERFAMILY SSF102405 23 149 2.14E-28 T 12-10-2018 VAPA_1c51440 e8c10731f1e86e40d458b7f0512ee593 173 TIGRFAM TIGR00725 TIGR00725: TIGR00725 family protein 27 148 3.7E-34 T 12-10-2018 IPR005268 Conserved hypothetical protein CHP00725 VAPA_1c51440 e8c10731f1e86e40d458b7f0512ee593 173 Gene3D G3DSA:3.40.50.450 15 171 3.2E-34 T 12-10-2018 VAPA_1c07880 47726f35825b998e9261c847697fd8c4 187 Gene3D G3DSA:3.40.630.30 3 164 2.2E-44 T 12-10-2018 VAPA_1c07880 47726f35825b998e9261c847697fd8c4 187 Pfam PF13302 Acetyltransferase (GNAT) domain 15 156 6.8E-31 T 12-10-2018 IPR000182 GNAT domain VAPA_1c07880 47726f35825b998e9261c847697fd8c4 187 SUPERFAMILY SSF55729 7 157 4.83E-40 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase VAPA_1c39180 53f93a6f921b23040a58a3d8b95faa63 317 SUPERFAMILY SSF53659 12 305 4.11E-67 T 12-10-2018 VAPA_1c39180 53f93a6f921b23040a58a3d8b95faa63 317 PIRSF PIRSF000428 11 308 4.3E-87 T 12-10-2018 IPR012147 Phosphate acetyl/butyryltransferase GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 VAPA_1c39180 53f93a6f921b23040a58a3d8b95faa63 317 Gene3D G3DSA:3.40.718.10 12 307 6.9E-94 T 12-10-2018 VAPA_1c39180 53f93a6f921b23040a58a3d8b95faa63 317 Pfam PF01515 Phosphate acetyl/butaryl transferase 89 299 2.6E-44 T 12-10-2018 IPR002505 Phosphate acetyl/butaryl transferase GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 VAPA_1c00960 25f58796f21459bdd6a1d50ee795c248 475 Gene3D G3DSA:1.10.620.20 3 475 3.1E-231 T 12-10-2018 IPR012348 Ribonucleotide reductase-like GO:0016491|GO:0055114 Reactome: R-HSA-499943 VAPA_1c00960 25f58796f21459bdd6a1d50ee795c248 475 SUPERFAMILY SSF47240 107 363 3.24E-47 T 12-10-2018 IPR009078 Ferritin-like superfamily VAPA_1c00960 25f58796f21459bdd6a1d50ee795c248 475 TIGRFAM TIGR03225 benzo_boxB: benzoyl-CoA oxygenase, B subunit 4 474 1.2E-268 T 12-10-2018 IPR017635 Benzoyl-CoA oxygenase, B subunit KEGG: 00362+1.14.13.208|MetaCyc: PWY-1361 VAPA_2c10520 6eb771094b5e0de86e1e02e1d1c9ac97 309 SMART SM00342 219 302 2.4E-30 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 VAPA_2c10520 6eb771094b5e0de86e1e02e1d1c9ac97 309 SUPERFAMILY SSF46689 256 306 3.88E-13 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 VAPA_2c10520 6eb771094b5e0de86e1e02e1d1c9ac97 309 SUPERFAMILY SSF46689 206 252 1.12E-10 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 VAPA_2c10520 6eb771094b5e0de86e1e02e1d1c9ac97 309 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 256 298 - T 12-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 VAPA_2c10520 6eb771094b5e0de86e1e02e1d1c9ac97 309 Gene3D G3DSA:1.10.10.60 262 307 4.5E-13 T 12-10-2018 VAPA_2c10520 6eb771094b5e0de86e1e02e1d1c9ac97 309 Gene3D G3DSA:1.10.10.60 202 261 4.1E-16 T 12-10-2018 VAPA_2c10520 6eb771094b5e0de86e1e02e1d1c9ac97 309 Pfam PF12833 Helix-turn-helix domain 225 304 2.2E-23 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 VAPA_2c04270 82eea34378d7d6cd56a9462b7d5bb781 160 Pfam PF00571 CBS domain 13 70 5.6E-10 T 12-10-2018 IPR000644 CBS domain VAPA_2c04270 82eea34378d7d6cd56a9462b7d5bb781 160 Pfam PF00571 CBS domain 83 138 1.5E-12 T 12-10-2018 IPR000644 CBS domain VAPA_2c04270 82eea34378d7d6cd56a9462b7d5bb781 160 SMART SM00116 19 72 1.6E-4 T 12-10-2018 IPR000644 CBS domain VAPA_2c04270 82eea34378d7d6cd56a9462b7d5bb781 160 SMART SM00116 90 138 1.8E-8 T 12-10-2018 IPR000644 CBS domain VAPA_2c04270 82eea34378d7d6cd56a9462b7d5bb781 160 SUPERFAMILY SSF54631 12 142 2.27E-29 T 12-10-2018 VAPA_2c04270 82eea34378d7d6cd56a9462b7d5bb781 160 Gene3D G3DSA:3.10.580.10 6 158 5.6E-35 T 12-10-2018 VAPA_1c37870 3d4f14a350278ff58d4559e5d3b631ff 218 Gene3D G3DSA:1.10.3720.10 1 215 1.2E-48 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c37870 3d4f14a350278ff58d4559e5d3b631ff 218 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 13 109 9.8E-31 T 12-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 VAPA_1c37870 3d4f14a350278ff58d4559e5d3b631ff 218 SUPERFAMILY SSF161098 12 204 2.94E-42 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c37870 3d4f14a350278ff58d4559e5d3b631ff 218 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 34 214 1.6E-16 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 VAPA_1c34320 f22d577f85e458b5ffef6c109a4c04bd 264 Gene3D G3DSA:3.30.450.40 90 264 1.2E-48 T 12-10-2018 IPR029016 GAF-like domain superfamily VAPA_1c34320 f22d577f85e458b5ffef6c109a4c04bd 264 Gene3D G3DSA:1.10.10.10 15 89 8.0E-18 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c34320 f22d577f85e458b5ffef6c109a4c04bd 264 Pfam PF09339 IclR helix-turn-helix domain 24 73 2.2E-12 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 VAPA_1c34320 f22d577f85e458b5ffef6c109a4c04bd 264 SMART SM00346 21 109 1.6E-30 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 VAPA_1c34320 f22d577f85e458b5ffef6c109a4c04bd 264 SUPERFAMILY SSF46785 23 93 1.29E-11 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c34320 f22d577f85e458b5ffef6c109a4c04bd 264 Pfam PF01614 Bacterial transcriptional regulator 137 262 1.2E-26 T 12-10-2018 IPR014757 Transcription regulator IclR, C-terminal VAPA_1c34320 f22d577f85e458b5ffef6c109a4c04bd 264 SUPERFAMILY SSF55781 85 261 2.26E-42 T 12-10-2018 VAPA_1c03270 42a255f59f041a2b3c3231daca94dd61 277 SUPERFAMILY SSF52540 31 256 1.93E-59 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c03270 42a255f59f041a2b3c3231daca94dd61 277 Gene3D G3DSA:3.40.50.300 29 268 5.1E-58 T 12-10-2018 VAPA_1c03270 42a255f59f041a2b3c3231daca94dd61 277 Pfam PF00005 ABC transporter 47 185 4.5E-28 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c03270 42a255f59f041a2b3c3231daca94dd61 277 SMART SM00382 55 236 3.4E-15 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c38820 00a8f0619736f1568af937581bf4e8a9 431 TIGRFAM TIGR01910 DapE-ArgE: peptidase, ArgE/DapE family 26 416 1.0E-88 T 12-10-2018 IPR010182 N-formyl-4-amino-5-aminomethyl-2-methylpyrimidine deformylase/Succinyl-diaminopimelate desuccinylase VAPA_1c38820 00a8f0619736f1568af937581bf4e8a9 431 SUPERFAMILY SSF55031 211 328 1.7E-12 T 12-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain VAPA_1c38820 00a8f0619736f1568af937581bf4e8a9 431 Gene3D G3DSA:3.40.630.10 33 426 1.5E-140 T 12-10-2018 VAPA_1c38820 00a8f0619736f1568af937581bf4e8a9 431 Pfam PF07687 Peptidase dimerisation domain 210 321 6.4E-15 T 12-10-2018 IPR011650 Peptidase M20, dimerisation domain VAPA_1c38820 00a8f0619736f1568af937581bf4e8a9 431 Gene3D G3DSA:3.30.70.360 211 338 1.5E-140 T 12-10-2018 VAPA_1c38820 00a8f0619736f1568af937581bf4e8a9 431 Pfam PF01546 Peptidase family M20/M25/M40 105 421 2.8E-35 T 12-10-2018 IPR002933 Peptidase M20 GO:0016787 VAPA_1c38820 00a8f0619736f1568af937581bf4e8a9 431 SUPERFAMILY SSF53187 14 426 4.86E-60 T 12-10-2018 VAPA_2c07800 8c6d72bce8bde28beaf0f122a534de15 341 Gene3D G3DSA:3.30.530.90 133 338 4.4E-55 T 12-10-2018 VAPA_2c07800 8c6d72bce8bde28beaf0f122a534de15 341 Pfam PF00355 Rieske [2Fe-2S] domain 7 89 2.3E-18 T 12-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 VAPA_2c07800 8c6d72bce8bde28beaf0f122a534de15 341 SUPERFAMILY SSF55961 104 337 6.04E-33 T 12-10-2018 VAPA_2c07800 8c6d72bce8bde28beaf0f122a534de15 341 SUPERFAMILY SSF50022 2 117 4.19E-33 T 12-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 VAPA_2c07800 8c6d72bce8bde28beaf0f122a534de15 341 Gene3D G3DSA:2.102.10.10 3 132 1.4E-36 T 12-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 VAPA_1c51210 e9edc532ce23e2a42b262e4d4c16305a 358 Pfam PF02653 Branched-chain amino acid transport system / permease component 47 316 2.4E-43 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 VAPA_2c06680 58215878adc793844a4327f27d4b15cf 291 SUPERFAMILY SSF51556 4 288 1.02E-61 T 12-10-2018 IPR032466 Metal-dependent hydrolase VAPA_2c06680 58215878adc793844a4327f27d4b15cf 291 Pfam PF04909 Amidohydrolase 5 288 2.0E-34 T 12-10-2018 IPR006680 Amidohydrolase-related GO:0016787 VAPA_2c06680 58215878adc793844a4327f27d4b15cf 291 Gene3D G3DSA:3.20.20.140 2 291 1.3E-82 T 12-10-2018 VAPA_1c27350 03ae9eee6acd78f108b95f4fa8e1f695 479 Gene3D G3DSA:1.20.210.10 6 475 1.0E-202 T 12-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 VAPA_1c27350 03ae9eee6acd78f108b95f4fa8e1f695 479 TIGRFAM TIGR00780 ccoN: cytochrome c oxidase, cbb3-type, subunit I 11 475 2.8E-234 T 12-10-2018 IPR004677 Cytochrome c oxidase cbb3-type, subunit I GO:0004129|GO:0045278|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 VAPA_1c27350 03ae9eee6acd78f108b95f4fa8e1f695 479 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 205 260 - T 12-10-2018 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 VAPA_1c27350 03ae9eee6acd78f108b95f4fa8e1f695 479 SUPERFAMILY SSF81442 11 469 1.31E-123 T 12-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 VAPA_1c27350 03ae9eee6acd78f108b95f4fa8e1f695 479 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 15 445 4.0E-112 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 VAPA_1c49490 dcf3e6397a4859bcb38c96b2554bffb2 357 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 82 330 1.3E-39 T 12-10-2018 IPR011234 Fumarylacetoacetase-like, C-terminal GO:0003824 VAPA_1c49490 dcf3e6397a4859bcb38c96b2554bffb2 357 SUPERFAMILY SSF56529 77 333 1.7E-56 T 12-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 VAPA_1c49490 dcf3e6397a4859bcb38c96b2554bffb2 357 Gene3D G3DSA:3.90.850.10 1 335 1.1E-142 T 12-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 VAPA_1c49450 cb820c19b80f0e79537e3f1ca805117a 324 Gene3D G3DSA:3.40.190.10 126 249 3.9E-110 T 12-10-2018 VAPA_1c49450 cb820c19b80f0e79537e3f1ca805117a 324 Gene3D G3DSA:3.40.190.150 28 314 3.9E-110 T 12-10-2018 VAPA_1c49450 cb820c19b80f0e79537e3f1ca805117a 324 SUPERFAMILY SSF53850 112 292 1.68E-12 T 12-10-2018 VAPA_1c49450 cb820c19b80f0e79537e3f1ca805117a 324 PIRSF PIRSF017082 1 323 2.6E-77 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c49450 cb820c19b80f0e79537e3f1ca805117a 324 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 47 320 1.5E-91 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c02840 e4d062690ddacf40d51159075a2d4eee 162 SUPERFAMILY SSF52833 2 160 1.58E-61 T 12-10-2018 IPR036249 Thioredoxin-like superfamily VAPA_1c02840 e4d062690ddacf40d51159075a2d4eee 162 PRINTS PR01011 Glutathione peroxidase family signature 22 39 1.9E-18 T 12-10-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 VAPA_1c02840 e4d062690ddacf40d51159075a2d4eee 162 PRINTS PR01011 Glutathione peroxidase family signature 57 73 1.9E-18 T 12-10-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 VAPA_1c02840 e4d062690ddacf40d51159075a2d4eee 162 PRINTS PR01011 Glutathione peroxidase family signature 123 132 1.9E-18 T 12-10-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 VAPA_1c02840 e4d062690ddacf40d51159075a2d4eee 162 Gene3D G3DSA:3.40.30.10 1 162 4.3E-72 T 12-10-2018 VAPA_1c02840 e4d062690ddacf40d51159075a2d4eee 162 ProSitePatterns PS00763 Glutathione peroxidases signature 2. 60 67 - T 12-10-2018 IPR029760 Glutathione peroxidase conserved site Reactome: R-HSA-3299685 VAPA_1c02840 e4d062690ddacf40d51159075a2d4eee 162 ProSitePatterns PS00460 Glutathione peroxidases active site. 24 39 - T 12-10-2018 IPR029759 Glutathione peroxidase active site Reactome: R-HSA-3299685 VAPA_1c02840 e4d062690ddacf40d51159075a2d4eee 162 Pfam PF00255 Glutathione peroxidase 4 110 2.6E-43 T 12-10-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 VAPA_1c02840 e4d062690ddacf40d51159075a2d4eee 162 PIRSF PIRSF000303 1 162 3.6E-68 T 12-10-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 VAPA_1c16730 d403d78b9ae2afc4e000e737bff952ef 451 Gene3D G3DSA:3.40.640.10 73 353 1.6E-146 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 VAPA_1c16730 d403d78b9ae2afc4e000e737bff952ef 451 SUPERFAMILY SSF53383 23 448 1.51E-115 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase VAPA_1c16730 d403d78b9ae2afc4e000e737bff952ef 451 Pfam PF00202 Aminotransferase class-III 39 447 6.7E-87 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 VAPA_1c16730 d403d78b9ae2afc4e000e737bff952ef 451 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 259 296 - T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 VAPA_1c16730 d403d78b9ae2afc4e000e737bff952ef 451 PIRSF PIRSF000521 145 450 2.1E-16 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 VAPA_1c16730 d403d78b9ae2afc4e000e737bff952ef 451 PIRSF PIRSF000521 32 154 2.5E-5 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 VAPA_1c16730 d403d78b9ae2afc4e000e737bff952ef 451 Gene3D G3DSA:3.90.1150.10 36 442 1.6E-146 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 VAPA_1c39490 8275cd79e4ce3bf2c8903aeb75c8030e 437 Pfam PF07690 Major Facilitator Superfamily 252 426 1.1E-13 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 VAPA_1c39490 8275cd79e4ce3bf2c8903aeb75c8030e 437 Pfam PF00083 Sugar (and other) transporter 13 221 1.9E-21 T 12-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 VAPA_1c39490 8275cd79e4ce3bf2c8903aeb75c8030e 437 SUPERFAMILY SSF103473 6 423 1.11E-61 T 12-10-2018 IPR036259 MFS transporter superfamily VAPA_1c39490 8275cd79e4ce3bf2c8903aeb75c8030e 437 Gene3D G3DSA:1.20.1250.20 10 426 1.7E-56 T 12-10-2018 VAPA_1c54570 78197f5b62f22fb98231ffa9d87a65fd 539 SMART SM01118 3 214 1.9E-29 T 12-10-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 VAPA_1c54570 78197f5b62f22fb98231ffa9d87a65fd 539 Gene3D G3DSA:1.40.20.10 230 527 1.5E-38 T 12-10-2018 IPR038186 CHAD domain superfamily VAPA_1c54570 78197f5b62f22fb98231ffa9d87a65fd 539 Pfam PF05235 CHAD domain 244 493 4.3E-32 T 12-10-2018 IPR007899 CHAD domain VAPA_1c54570 78197f5b62f22fb98231ffa9d87a65fd 539 Pfam PF01928 CYTH domain 4 207 6.2E-18 T 12-10-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 VAPA_1c54570 78197f5b62f22fb98231ffa9d87a65fd 539 SMART SM00880 243 528 3.2E-44 T 12-10-2018 IPR007899 CHAD domain VAPA_1c54570 78197f5b62f22fb98231ffa9d87a65fd 539 Gene3D G3DSA:2.40.320.10 2 210 9.5E-25 T 12-10-2018 VAPA_1c54570 78197f5b62f22fb98231ffa9d87a65fd 539 SUPERFAMILY SSF55154 3 222 4.09E-31 T 12-10-2018 IPR033469 CYTH-like domain superfamily Reactome: R-HSA-196819 VAPA_2c01320 ed87595d53cebe2eb9373ffbb4a6aaa3 325 SUPERFAMILY SSF53850 115 279 2.82E-6 T 12-10-2018 VAPA_2c01320 ed87595d53cebe2eb9373ffbb4a6aaa3 325 PIRSF PIRSF017082 1 325 1.4E-64 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_2c01320 ed87595d53cebe2eb9373ffbb4a6aaa3 325 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 49 322 3.6E-78 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_2c01320 ed87595d53cebe2eb9373ffbb4a6aaa3 325 Gene3D G3DSA:3.40.190.150 30 315 1.3E-100 T 12-10-2018 VAPA_2c01320 ed87595d53cebe2eb9373ffbb4a6aaa3 325 Gene3D G3DSA:3.40.190.10 127 250 1.3E-100 T 12-10-2018 VAPA_1c08430 26bfe3410e7c94b11a4e4922ef78f0ee 354 Gene3D G3DSA:3.30.1370.60 62 281 3.1E-110 T 12-10-2018 VAPA_1c08430 26bfe3410e7c94b11a4e4922ef78f0ee 354 Gene3D G3DSA:1.10.1530.10 10 348 3.1E-110 T 12-10-2018 VAPA_1c08430 26bfe3410e7c94b11a4e4922ef78f0ee 354 Gene3D G3DSA:1.20.5.460 282 311 3.1E-110 T 12-10-2018 VAPA_1c08430 26bfe3410e7c94b11a4e4922ef78f0ee 354 Pfam PF02615 Malate/L-lactate dehydrogenase 8 340 2.6E-111 T 12-10-2018 IPR003767 Malate/L-lactate dehydrogenase-like GO:0016491|GO:0055114 VAPA_1c08430 26bfe3410e7c94b11a4e4922ef78f0ee 354 SUPERFAMILY SSF89733 5 349 2.35E-101 T 12-10-2018 IPR036111 Malate/L-sulfolactate/L-lactate dehydrogenase-like superfamily GO:0016491|GO:0055114 VAPA_1c49050 55f11d1e86a25f676c3b11ec53b23064 239 Gene3D G3DSA:3.40.1050.10 42 239 2.8E-60 T 12-10-2018 IPR036874 Carbonic anhydrase superfamily GO:0004089|GO:0008270 VAPA_1c49050 55f11d1e86a25f676c3b11ec53b23064 239 Pfam PF00484 Carbonic anhydrase 88 236 8.1E-39 T 12-10-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 VAPA_1c49050 55f11d1e86a25f676c3b11ec53b23064 239 SMART SM00947 80 239 3.9E-51 T 12-10-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 VAPA_1c49050 55f11d1e86a25f676c3b11ec53b23064 239 ProSitePatterns PS00704 Prokaryotic-type carbonic anhydrases signature 1. 92 99 - T 12-10-2018 IPR015892 Carbonic anhydrase, prokaryotic-like, conserved site GO:0004089|GO:0008270|GO:0015976 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 VAPA_1c49050 55f11d1e86a25f676c3b11ec53b23064 239 SUPERFAMILY SSF53056 48 239 6.93E-53 T 12-10-2018 IPR036874 Carbonic anhydrase superfamily GO:0004089|GO:0008270 VAPA_1c36630 6bbee58cd9d6b99f5bb34ab977384ea0 611 Pfam PF01019 Gamma-glutamyltranspeptidase 29 603 1.1E-109 T 12-10-2018 VAPA_1c36630 6bbee58cd9d6b99f5bb34ab977384ea0 611 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 35 60 3.2E-16 T 12-10-2018 VAPA_1c36630 6bbee58cd9d6b99f5bb34ab977384ea0 611 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 440 458 3.2E-16 T 12-10-2018 VAPA_1c36630 6bbee58cd9d6b99f5bb34ab977384ea0 611 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 417 435 3.2E-16 T 12-10-2018 VAPA_1c36630 6bbee58cd9d6b99f5bb34ab977384ea0 611 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 471 486 3.2E-16 T 12-10-2018 VAPA_1c36630 6bbee58cd9d6b99f5bb34ab977384ea0 611 SUPERFAMILY SSF56235 2 610 8.16E-123 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal VAPA_1c36630 6bbee58cd9d6b99f5bb34ab977384ea0 611 Gene3D G3DSA:3.60.20.40 417 610 2.4E-45 T 12-10-2018 VAPA_1c36630 6bbee58cd9d6b99f5bb34ab977384ea0 611 Gene3D G3DSA:1.10.246.130 263 383 7.2E-16 T 12-10-2018 VAPA_2c12050 bcf9b9ae316e5fc29f9eb887a4a4512f 401 Gene3D G3DSA:3.90.1150.10 9 396 3.4E-145 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 VAPA_2c12050 bcf9b9ae316e5fc29f9eb887a4a4512f 401 Pfam PF00155 Aminotransferase class I and II 31 396 4.0E-68 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 VAPA_2c12050 bcf9b9ae316e5fc29f9eb887a4a4512f 401 Gene3D G3DSA:3.40.640.10 63 303 3.4E-145 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 VAPA_2c12050 bcf9b9ae316e5fc29f9eb887a4a4512f 401 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 246 259 - T 12-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 VAPA_2c12050 bcf9b9ae316e5fc29f9eb887a4a4512f 401 SUPERFAMILY SSF53383 1 400 4.2E-104 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase VAPA_2c12050 bcf9b9ae316e5fc29f9eb887a4a4512f 401 PRINTS PR00799 Aspartate aminotransferase signature 345 363 7.7E-33 T 12-10-2018 IPR000796 Aspartate/other aminotransferase GO:0006520|GO:0008483 KEGG: 00220+2.6.1.1|KEGG: 00250+2.6.1.1|KEGG: 00270+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 VAPA_2c12050 bcf9b9ae316e5fc29f9eb887a4a4512f 401 PRINTS PR00799 Aspartate aminotransferase signature 276 301 7.7E-33 T 12-10-2018 IPR000796 Aspartate/other aminotransferase GO:0006520|GO:0008483 KEGG: 00220+2.6.1.1|KEGG: 00250+2.6.1.1|KEGG: 00270+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 VAPA_2c12050 bcf9b9ae316e5fc29f9eb887a4a4512f 401 PRINTS PR00799 Aspartate aminotransferase signature 209 221 7.7E-33 T 12-10-2018 IPR000796 Aspartate/other aminotransferase GO:0006520|GO:0008483 KEGG: 00220+2.6.1.1|KEGG: 00250+2.6.1.1|KEGG: 00270+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 VAPA_2c12050 bcf9b9ae316e5fc29f9eb887a4a4512f 401 PRINTS PR00799 Aspartate aminotransferase signature 178 197 7.7E-33 T 12-10-2018 IPR000796 Aspartate/other aminotransferase GO:0006520|GO:0008483 KEGG: 00220+2.6.1.1|KEGG: 00250+2.6.1.1|KEGG: 00270+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 VAPA_1c45930 c5e9cb72c1831c2f6393b422246f33f3 407 SUPERFAMILY SSF103365 8 407 1.22E-137 T 12-10-2018 IPR036025 tRNA-splicing ligase RtcB-like superfamily GO:0006396|GO:0008452 Reactome: R-HSA-6784531 VAPA_1c45930 c5e9cb72c1831c2f6393b422246f33f3 407 Gene3D G3DSA:3.90.1860.10 2 407 6.1E-115 T 12-10-2018 IPR036025 tRNA-splicing ligase RtcB-like superfamily GO:0006396|GO:0008452 Reactome: R-HSA-6784531 VAPA_1c45930 c5e9cb72c1831c2f6393b422246f33f3 407 Pfam PF01139 tRNA-splicing ligase RtcB 32 407 4.3E-130 T 12-10-2018 IPR001233 tRNA-splicing ligase, RtcB GO:0006396|GO:0008452 Reactome: R-HSA-6784531 VAPA_1c09080 35a8428988b691f79cc83b7929a0796d 172 SUPERFAMILY SSF51182 11 169 2.36E-46 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily VAPA_1c09080 35a8428988b691f79cc83b7929a0796d 172 Pfam PF04115 Ureidoglycolate lyase 12 168 9.3E-42 T 12-10-2018 IPR007247 Ureidoglycolate lyase GO:0000256|GO:0050385 KEGG: 00230+4.3.2.3|MetaCyc: PWY-5694|MetaCyc: PWY-5705 VAPA_1c09080 35a8428988b691f79cc83b7929a0796d 172 Gene3D G3DSA:2.60.120.480 11 171 7.4E-47 T 12-10-2018 IPR024060 Ureidoglycolate lyase domain superfamily GO:0004848 KEGG: 00230+4.3.2.3|MetaCyc: PWY-5694|MetaCyc: PWY-5705 VAPA_1c09080 35a8428988b691f79cc83b7929a0796d 172 PIRSF PIRSF017306 10 167 4.1E-25 T 12-10-2018 IPR007247 Ureidoglycolate lyase GO:0000256|GO:0050385 KEGG: 00230+4.3.2.3|MetaCyc: PWY-5694|MetaCyc: PWY-5705 VAPA_2c10640 040c1c57f63b68594271371a455db387 239 PIRSF PIRSF006232 1 237 5.2E-56 T 12-10-2018 IPR012093 Pirin Reactome: R-HSA-8935690 VAPA_2c10640 040c1c57f63b68594271371a455db387 239 Gene3D G3DSA:2.60.120.10 7 231 1.3E-91 T 12-10-2018 IPR014710 RmlC-like jelly roll fold VAPA_2c10640 040c1c57f63b68594271371a455db387 239 Pfam PF02678 Pirin 13 119 1.7E-34 T 12-10-2018 IPR003829 Pirin, N-terminal domain Reactome: R-HSA-8935690 VAPA_2c10640 040c1c57f63b68594271371a455db387 239 SUPERFAMILY SSF51182 1 233 3.66E-80 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily VAPA_2c10640 040c1c57f63b68594271371a455db387 239 Gene3D G3DSA:2.60.120.10 11 135 1.3E-91 T 12-10-2018 IPR014710 RmlC-like jelly roll fold VAPA_2c10770 ac47833d105b905295c0fe636058b795 258 Gene3D G3DSA:3.90.226.10 2 258 3.5E-77 T 12-10-2018 VAPA_2c10770 ac47833d105b905295c0fe636058b795 258 SUPERFAMILY SSF52096 3 258 3.22E-75 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily VAPA_2c10770 ac47833d105b905295c0fe636058b795 258 Pfam PF00378 Enoyl-CoA hydratase/isomerase 13 257 7.5E-51 T 12-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 VAPA_2c04220 c1759db7af4b81cdf118619852348725 249 SMART SM00387 109 220 3.4E-13 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase VAPA_2c04220 c1759db7af4b81cdf118619852348725 249 Gene3D G3DSA:3.30.565.10 71 227 4.0E-26 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_2c04220 c1759db7af4b81cdf118619852348725 249 PRINTS PR00344 Bacterial sensor protein C-terminal signature 149 163 1.1E-8 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_2c04220 c1759db7af4b81cdf118619852348725 249 PRINTS PR00344 Bacterial sensor protein C-terminal signature 180 198 1.1E-8 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_2c04220 c1759db7af4b81cdf118619852348725 249 PRINTS PR00344 Bacterial sensor protein C-terminal signature 167 177 1.1E-8 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_2c04220 c1759db7af4b81cdf118619852348725 249 PRINTS PR00344 Bacterial sensor protein C-terminal signature 204 217 1.1E-8 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_2c04220 c1759db7af4b81cdf118619852348725 249 SUPERFAMILY SSF55874 67 218 8.51E-27 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_2c04220 c1759db7af4b81cdf118619852348725 249 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 110 217 1.8E-9 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase VAPA_2c01630 d5121caf5cda82be36bfe8347fd5842d 374 PIRSF PIRSF001361 14 372 1.5E-157 T 12-10-2018 IPR006219 DHAP synthase, class 1 GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 VAPA_2c01630 d5121caf5cda82be36bfe8347fd5842d 374 SUPERFAMILY SSF51569 27 368 4.3E-133 T 12-10-2018 VAPA_2c01630 d5121caf5cda82be36bfe8347fd5842d 374 Gene3D G3DSA:3.20.20.70 22 370 8.1E-155 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 VAPA_2c01630 d5121caf5cda82be36bfe8347fd5842d 374 Pfam PF00793 DAHP synthetase I family 64 354 1.3E-101 T 12-10-2018 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 VAPA_2c01630 d5121caf5cda82be36bfe8347fd5842d 374 TIGRFAM TIGR00034 aroFGH: 3-deoxy-7-phosphoheptulonate synthase 26 369 1.5E-155 T 12-10-2018 IPR006219 DHAP synthase, class 1 GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 VAPA_1c34790 036b3b615d8dcb611b6f62a20c11f667 91 SUPERFAMILY SSF47336 12 88 1.57E-11 T 12-10-2018 IPR036736 ACP-like superfamily VAPA_1c34790 036b3b615d8dcb611b6f62a20c11f667 91 Gene3D G3DSA:1.10.1200.10 10 90 5.9E-14 T 12-10-2018 IPR036736 ACP-like superfamily VAPA_1c34790 036b3b615d8dcb611b6f62a20c11f667 91 Pfam PF00550 Phosphopantetheine attachment site 31 85 1.0E-5 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain VAPA_1c54290 9f9b64320dba06b99850e71adbb6bc94 311 Pfam PF05544 Proline racemase 6 309 1.2E-101 T 12-10-2018 IPR008794 Proline racemase family VAPA_1c54290 9f9b64320dba06b99850e71adbb6bc94 311 PIRSF PIRSF029792 1 311 6.3E-94 T 12-10-2018 IPR008794 Proline racemase family VAPA_1c54290 9f9b64320dba06b99850e71adbb6bc94 311 Gene3D G3DSA:3.10.310.10 134 287 7.3E-110 T 12-10-2018 VAPA_1c54290 9f9b64320dba06b99850e71adbb6bc94 311 Gene3D G3DSA:3.10.310.10 5 305 7.3E-110 T 12-10-2018 VAPA_1c54290 9f9b64320dba06b99850e71adbb6bc94 311 SUPERFAMILY SSF54506 2 309 1.04E-96 T 12-10-2018 VAPA_1c22140 c6d2a1aa21e53acf6e0d2455cce5320e 147 SUPERFAMILY SSF54637 12 143 1.71E-23 T 12-10-2018 IPR029069 HotDog domain superfamily VAPA_1c22140 c6d2a1aa21e53acf6e0d2455cce5320e 147 Pfam PF01575 MaoC like domain 11 119 8.9E-17 T 12-10-2018 IPR002539 MaoC-like dehydratase domain VAPA_1c22140 c6d2a1aa21e53acf6e0d2455cce5320e 147 Gene3D G3DSA:3.10.129.10 5 142 1.5E-26 T 12-10-2018 VAPA_1c15650 e78f64b220d1dd97e917dd91549b71ce 87 SUPERFAMILY SSF54565 1 77 9.55E-28 T 12-10-2018 IPR023803 Ribosomal protein S16 domain superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 VAPA_1c15650 e78f64b220d1dd97e917dd91549b71ce 87 Gene3D G3DSA:3.30.1320.10 1 87 8.5E-30 T 12-10-2018 IPR023803 Ribosomal protein S16 domain superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 VAPA_1c15650 e78f64b220d1dd97e917dd91549b71ce 87 Hamap MF_00385 30S ribosomal protein S16 [rpsP]. 1 78 22.32 T 12-10-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 VAPA_1c15650 e78f64b220d1dd97e917dd91549b71ce 87 TIGRFAM TIGR00002 S16: ribosomal protein bS16 2 79 5.9E-26 T 12-10-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 VAPA_1c15650 e78f64b220d1dd97e917dd91549b71ce 87 Pfam PF00886 Ribosomal protein S16 8 68 1.3E-22 T 12-10-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 VAPA_1c51700 3520fd808ac22c36546c93747bc45a48 238 Pfam PF00230 Major intrinsic protein 6 229 3.4E-49 T 12-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 VAPA_1c51700 3520fd808ac22c36546c93747bc45a48 238 SUPERFAMILY SSF81338 9 235 3.27E-63 T 12-10-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 VAPA_1c51700 3520fd808ac22c36546c93747bc45a48 238 TIGRFAM TIGR00861 MIP: MIP family channel proteins 14 229 9.3E-56 T 12-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 VAPA_1c51700 3520fd808ac22c36546c93747bc45a48 238 PRINTS PR00783 Major intrinsic protein family signature 88 107 7.4E-51 T 12-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 VAPA_1c51700 3520fd808ac22c36546c93747bc45a48 238 PRINTS PR00783 Major intrinsic protein family signature 51 75 7.4E-51 T 12-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 VAPA_1c51700 3520fd808ac22c36546c93747bc45a48 238 PRINTS PR00783 Major intrinsic protein family signature 212 232 7.4E-51 T 12-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 VAPA_1c51700 3520fd808ac22c36546c93747bc45a48 238 PRINTS PR00783 Major intrinsic protein family signature 143 161 7.4E-51 T 12-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 VAPA_1c51700 3520fd808ac22c36546c93747bc45a48 238 PRINTS PR00783 Major intrinsic protein family signature 173 195 7.4E-51 T 12-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 VAPA_1c51700 3520fd808ac22c36546c93747bc45a48 238 PRINTS PR00783 Major intrinsic protein family signature 10 29 7.4E-51 T 12-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 VAPA_1c51700 3520fd808ac22c36546c93747bc45a48 238 Hamap MF_01146 Aquaporin Z [aqpZ]. 9 236 33.016 T 12-10-2018 IPR023743 Aquaporin Z GO:0006833|GO:0015250|GO:0016021|GO:0055085 VAPA_1c51700 3520fd808ac22c36546c93747bc45a48 238 ProSitePatterns PS00221 MIP family signature. 69 77 - T 12-10-2018 IPR022357 Major intrinsic protein, conserved site Reactome: R-HSA-432047 VAPA_1c51700 3520fd808ac22c36546c93747bc45a48 238 Gene3D G3DSA:1.20.1080.10 3 235 1.3E-79 T 12-10-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 VAPA_1c27610 2a0231fefb55376891e51758cf01fdda 167 Pfam PF03928 Haem-degrading 35 160 4.4E-26 T 12-10-2018 IPR005624 Haem-degrading VAPA_1c27610 2a0231fefb55376891e51758cf01fdda 167 Gene3D G3DSA:3.30.450.150 17 163 8.6E-39 T 12-10-2018 IPR038084 GlcG-like domain superfamily VAPA_1c27610 2a0231fefb55376891e51758cf01fdda 167 SUPERFAMILY SSF143744 29 162 1.83E-33 T 12-10-2018 IPR038084 GlcG-like domain superfamily VAPA_1c07280 cbaced6339f3d25ad29b367de9310a61 340 TIGRFAM TIGR01245 trpD: anthranilate phosphoribosyltransferase 8 335 6.5E-128 T 12-10-2018 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 VAPA_1c07280 cbaced6339f3d25ad29b367de9310a61 340 SUPERFAMILY SSF47648 3 70 3.14E-16 T 12-10-2018 IPR036320 Glycosyl transferase family 3, N-terminal domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 VAPA_1c07280 cbaced6339f3d25ad29b367de9310a61 340 Pfam PF02885 Glycosyl transferase family, helical bundle domain 6 65 2.2E-11 T 12-10-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 VAPA_1c07280 cbaced6339f3d25ad29b367de9310a61 340 SUPERFAMILY SSF52418 77 337 4.32E-98 T 12-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 VAPA_1c07280 cbaced6339f3d25ad29b367de9310a61 340 Gene3D G3DSA:1.20.970.10 1 71 1.1E-31 T 12-10-2018 VAPA_1c07280 cbaced6339f3d25ad29b367de9310a61 340 Hamap MF_00211 Anthranilate phosphoribosyltransferase [trpD]. 6 336 37.615 T 12-10-2018 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 VAPA_1c07280 cbaced6339f3d25ad29b367de9310a61 340 Pfam PF00591 Glycosyl transferase family, a/b domain 77 326 2.7E-96 T 12-10-2018 IPR000312 Glycosyl transferase, family 3 GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 VAPA_1c07280 cbaced6339f3d25ad29b367de9310a61 340 Gene3D G3DSA:3.40.1030.10 72 340 4.2E-110 T 12-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 VAPA_2c06840 1153136460268de0431196525804a44e 438 SUPERFAMILY SSF51905 13 408 4.82E-25 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_2c06840 1153136460268de0431196525804a44e 438 Gene3D G3DSA:3.50.50.60 16 196 4.7E-16 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_2c06840 1153136460268de0431196525804a44e 438 Pfam PF12831 FAD dependent oxidoreductase 18 430 2.2E-98 T 12-10-2018 IPR039649 Digeranylgeranylglycerophospholipid reductase, N-terminal VAPA_1c08940 b6f62b5a1f2ab1c5db75329b95c3a041 562 SUPERFAMILY SSF56672 143 462 1.45E-53 T 12-10-2018 VAPA_1c08940 b6f62b5a1f2ab1c5db75329b95c3a041 562 TIGRFAM TIGR04416 group_II_RT_mat: group II intron reverse transcriptase/maturase 148 516 1.4E-104 T 12-10-2018 IPR030931 Group II intron reverse transcriptase/maturase VAPA_1c08940 b6f62b5a1f2ab1c5db75329b95c3a041 562 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 202 432 3.8E-41 T 12-10-2018 IPR000477 Reverse transcriptase domain VAPA_1c29990 bae892c58ec7b1994a383b3dd70bdda5 189 TIGRFAM TIGR00708 cobA: cob(I)yrinic acid a,c-diamide adenosyltransferase 18 188 1.4E-59 T 12-10-2018 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17 VAPA_1c29990 bae892c58ec7b1994a383b3dd70bdda5 189 Pfam PF02572 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP 20 188 3.8E-59 T 12-10-2018 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17 VAPA_1c29990 bae892c58ec7b1994a383b3dd70bdda5 189 Gene3D G3DSA:3.40.50.300 7 188 3.0E-62 T 12-10-2018 VAPA_1c29990 bae892c58ec7b1994a383b3dd70bdda5 189 PIRSF PIRSF015617 2 189 2.4E-62 T 12-10-2018 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17 VAPA_1c29990 bae892c58ec7b1994a383b3dd70bdda5 189 SUPERFAMILY SSF52540 18 188 2.54E-61 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c21200 55b7f4a832b2c9f97f3dc222db2ed93c 112 Gene3D G3DSA:2.30.30.240 2 88 3.3E-26 T 12-10-2018 VAPA_1c21200 55b7f4a832b2c9f97f3dc222db2ed93c 112 SUPERFAMILY SSF50346 7 111 5.89E-26 T 12-10-2018 IPR011033 PRC-barrel-like superfamily VAPA_1c21200 55b7f4a832b2c9f97f3dc222db2ed93c 112 Pfam PF05239 PRC-barrel domain 9 83 6.2E-14 T 12-10-2018 IPR027275 PRC-barrel domain VAPA_1c35750 76c4f8f6b8fd0ea876847b6e6a03f903 332 Pfam PF12146 Serine aminopeptidase, S33 82 189 1.0E-15 T 12-10-2018 IPR022742 Serine aminopeptidase, S33 VAPA_1c35750 76c4f8f6b8fd0ea876847b6e6a03f903 332 PRINTS PR00111 Alpha/beta hydrolase fold signature 109 124 5.3E-5 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 VAPA_1c35750 76c4f8f6b8fd0ea876847b6e6a03f903 332 PRINTS PR00111 Alpha/beta hydrolase fold signature 155 168 5.3E-5 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 VAPA_1c35750 76c4f8f6b8fd0ea876847b6e6a03f903 332 SUPERFAMILY SSF53474 15 264 2.74E-36 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c35750 76c4f8f6b8fd0ea876847b6e6a03f903 332 Gene3D G3DSA:3.40.50.1820 56 279 1.4E-33 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_2c06360 cd22f8862e6b60fcac4a9fd06d29f86a 298 SUPERFAMILY SSF46689 180 229 3.05E-7 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 VAPA_2c06360 cd22f8862e6b60fcac4a9fd06d29f86a 298 Pfam PF12833 Helix-turn-helix domain 203 280 3.2E-16 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 VAPA_2c06360 cd22f8862e6b60fcac4a9fd06d29f86a 298 SUPERFAMILY SSF46689 234 280 2.78E-6 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 VAPA_2c06360 cd22f8862e6b60fcac4a9fd06d29f86a 298 SMART SM00342 197 279 2.2E-13 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 VAPA_2c06360 cd22f8862e6b60fcac4a9fd06d29f86a 298 Gene3D G3DSA:1.10.10.60 180 283 3.2E-20 T 12-10-2018 VAPA_1c15870 a88e57513e0ad6afbfd576c5847646cc 541 SUPERFAMILY SSF56801 4 524 6.54E-112 T 12-10-2018 VAPA_1c15870 a88e57513e0ad6afbfd576c5847646cc 541 ProSitePatterns PS00455 Putative AMP-binding domain signature. 167 178 - T 12-10-2018 IPR020845 AMP-binding, conserved site VAPA_1c15870 a88e57513e0ad6afbfd576c5847646cc 541 Pfam PF13193 AMP-binding enzyme C-terminal domain 431 511 2.0E-15 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain VAPA_1c15870 a88e57513e0ad6afbfd576c5847646cc 541 Gene3D G3DSA:3.40.50.12780 2 415 7.6E-79 T 12-10-2018 VAPA_1c15870 a88e57513e0ad6afbfd576c5847646cc 541 Pfam PF00501 AMP-binding enzyme 14 422 4.9E-68 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 VAPA_1c15870 a88e57513e0ad6afbfd576c5847646cc 541 Gene3D G3DSA:3.30.300.30 416 524 2.2E-27 T 12-10-2018 VAPA_1c29130 4c52011230301cf18b263afc0297b712 257 SUPERFAMILY SSF53448 3 251 2.25E-58 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases VAPA_1c29130 4c52011230301cf18b263afc0297b712 257 TIGRFAM TIGR00466 kdsB: 3-deoxy-D-manno-octulosonate cytidylyltransferase 2 245 1.5E-89 T 12-10-2018 IPR004528 3-deoxy-D-manno-octulosonate cytidylyltransferase GO:0005737|GO:0008690 KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269 VAPA_1c29130 4c52011230301cf18b263afc0297b712 257 Gene3D G3DSA:3.90.550.10 1 252 5.0E-90 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases VAPA_1c29130 4c52011230301cf18b263afc0297b712 257 Hamap MF_00057 8-amino-3,8-dideoxy-manno-octulosonate cytidylyltransferase [kdsB]. 1 252 41.294 T 12-10-2018 IPR004528 3-deoxy-D-manno-octulosonate cytidylyltransferase GO:0005737|GO:0008690 KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269 VAPA_1c29130 4c52011230301cf18b263afc0297b712 257 Pfam PF02348 Cytidylyltransferase 5 225 9.1E-53 T 12-10-2018 IPR003329 Acylneuraminate cytidylyltransferase KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269|Reactome: R-HSA-4085001 VAPA_1c26260 69e97cbfe4d93fac158476b3049f2b85 258 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 225 247 2.6E-8 T 12-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal VAPA_1c26260 69e97cbfe4d93fac158476b3049f2b85 258 Pfam PF00005 ABC transporter 23 178 2.6E-26 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c26260 69e97cbfe4d93fac158476b3049f2b85 258 SUPERFAMILY SSF52540 5 247 2.15E-53 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c26260 69e97cbfe4d93fac158476b3049f2b85 258 SMART SM00382 31 225 4.0E-9 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c26260 69e97cbfe4d93fac158476b3049f2b85 258 Gene3D G3DSA:3.40.50.300 5 254 9.3E-53 T 12-10-2018 VAPA_2c08670 0b641a25a15c38d52c6b08cbf83d5fd1 249 Pfam PF13618 Gluconate 2-dehydrogenase subunit 3 65 219 5.6E-19 T 12-10-2018 IPR027056 Gluconate 2-dehydrogenase subunit 3 KEGG: 00030+1.1.99.3|MetaCyc: PWY-7165 VAPA_1c28680 7e4a4279100da2ae1ff7cfe2aa88fd80 243 SUPERFAMILY SSF51735 4 242 2.22E-73 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c28680 7e4a4279100da2ae1ff7cfe2aa88fd80 243 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 6 190 1.1E-5 T 12-10-2018 VAPA_1c28680 7e4a4279100da2ae1ff7cfe2aa88fd80 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 4.1E-41 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c28680 7e4a4279100da2ae1ff7cfe2aa88fd80 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 4.1E-41 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c28680 7e4a4279100da2ae1ff7cfe2aa88fd80 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 4.1E-41 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c28680 7e4a4279100da2ae1ff7cfe2aa88fd80 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 4.1E-41 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c28680 7e4a4279100da2ae1ff7cfe2aa88fd80 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 206 226 4.1E-41 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c28680 7e4a4279100da2ae1ff7cfe2aa88fd80 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 4.1E-41 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c28680 7e4a4279100da2ae1ff7cfe2aa88fd80 243 Gene3D G3DSA:3.40.50.720 1 243 1.8E-77 T 12-10-2018 VAPA_1c28680 7e4a4279100da2ae1ff7cfe2aa88fd80 243 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 242 2.4E-53 T 12-10-2018 VAPA_1c28680 7e4a4279100da2ae1ff7cfe2aa88fd80 243 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 4.1E-11 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c28680 7e4a4279100da2ae1ff7cfe2aa88fd80 243 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 4.1E-11 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c28680 7e4a4279100da2ae1ff7cfe2aa88fd80 243 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 4.1E-11 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c23980 fe70c4d22c86643dd2d654140bdd4872 403 Pfam PF12536 Patatin phospholipase 275 376 8.2E-34 T 12-10-2018 IPR021095 Protein of unknown function DUF3734 VAPA_1c23980 fe70c4d22c86643dd2d654140bdd4872 403 Gene3D G3DSA:3.40.1090.10 148 291 4.5E-16 T 12-10-2018 VAPA_1c23980 fe70c4d22c86643dd2d654140bdd4872 403 Gene3D G3DSA:3.40.1090.10 17 103 1.6E-18 T 12-10-2018 VAPA_1c23980 fe70c4d22c86643dd2d654140bdd4872 403 SUPERFAMILY SSF52151 31 368 1.15E-53 T 12-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase VAPA_1c23980 fe70c4d22c86643dd2d654140bdd4872 403 Pfam PF01734 Patatin-like phospholipase 35 237 4.5E-26 T 12-10-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 VAPA_1c30000 cfb743737dff07681395f0e5688d53c2 259 SMART SM00382 31 221 4.8E-10 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c30000 cfb743737dff07681395f0e5688d53c2 259 Gene3D G3DSA:3.40.50.300 6 256 1.1E-53 T 12-10-2018 VAPA_1c30000 cfb743737dff07681395f0e5688d53c2 259 Pfam PF00005 ABC transporter 22 173 1.0E-23 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c30000 cfb743737dff07681395f0e5688d53c2 259 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_1c30000 cfb743737dff07681395f0e5688d53c2 259 SUPERFAMILY SSF52540 6 233 5.65E-50 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c35140 18a5772c52841e0a629efe8a04f00c20 387 Gene3D G3DSA:3.30.1540.10 230 322 3.6E-113 T 12-10-2018 VAPA_1c35140 18a5772c52841e0a629efe8a04f00c20 387 Pfam PF02515 CoA-transferase family III 8 371 4.8E-110 T 12-10-2018 IPR003673 CoA-transferase family III GO:0003824 VAPA_1c35140 18a5772c52841e0a629efe8a04f00c20 387 Gene3D G3DSA:3.40.50.10540 7 378 3.6E-113 T 12-10-2018 IPR023606 CoA-transferase family III domain superfamily VAPA_1c35140 18a5772c52841e0a629efe8a04f00c20 387 SUPERFAMILY SSF89796 6 378 8.37E-114 T 12-10-2018 IPR023606 CoA-transferase family III domain superfamily VAPA_1c42220 7779a172b626d3a14b84d9f91d89923e 227 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 34 219 1.4E-15 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 VAPA_1c42220 7779a172b626d3a14b84d9f91d89923e 227 SUPERFAMILY SSF161098 11 224 8.24E-49 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c42220 7779a172b626d3a14b84d9f91d89923e 227 TIGRFAM TIGR02141 modB_ABC: molybdate ABC transporter, permease protein 18 221 1.6E-67 T 12-10-2018 IPR011867 Molybdate ABC transporter, permease protein GO:0015098|GO:0015689|GO:0016021 VAPA_1c42220 7779a172b626d3a14b84d9f91d89923e 227 Gene3D G3DSA:1.10.3720.10 2 226 4.5E-58 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c08600 ee4a9670d51a8a620f59be9a6aba3fb6 174 Pfam PF00694 Aconitase C-terminal domain 58 110 8.1E-15 T 12-10-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain KEGG: 00290+4.2.1.33 VAPA_1c08600 ee4a9670d51a8a620f59be9a6aba3fb6 174 SUPERFAMILY SSF52016 9 164 8.83E-37 T 12-10-2018 VAPA_1c08600 ee4a9670d51a8a620f59be9a6aba3fb6 174 Gene3D G3DSA:3.20.19.10 8 174 7.8E-42 T 12-10-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel KEGG: 00290+4.2.1.33 VAPA_1c08600 ee4a9670d51a8a620f59be9a6aba3fb6 174 TIGRFAM TIGR02087 LEUD_arch: 3-isopropylmalate dehydratase, small subunit 11 162 1.1E-45 T 12-10-2018 IPR011827 Hydrolyase LeuD/HacB/DmdB GO:0016836 KEGG: 00290+4.2.1.33 VAPA_1c03540 be8353541d81c4905825428f72ba378c 319 Gene3D G3DSA:3.60.15.10 7 246 3.8E-42 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like VAPA_1c03540 be8353541d81c4905825428f72ba378c 319 Pfam PF00753 Metallo-beta-lactamase superfamily 37 221 6.2E-8 T 12-10-2018 IPR001279 Metallo-beta-lactamase VAPA_1c03540 be8353541d81c4905825428f72ba378c 319 SUPERFAMILY SSF56281 16 311 1.82E-55 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like VAPA_1c03540 be8353541d81c4905825428f72ba378c 319 SMART SM00849 35 222 3.4E-13 T 12-10-2018 IPR001279 Metallo-beta-lactamase VAPA_1c51000 74b277307f0d6067a52f9bebf820f8f3 699 Gene3D G3DSA:3.30.70.240 609 680 3.6E-90 T 12-10-2018 VAPA_1c51000 74b277307f0d6067a52f9bebf820f8f3 699 SUPERFAMILY SSF54980 608 694 2.97E-28 T 12-10-2018 IPR035647 EF-G domain III/V-like VAPA_1c51000 74b277307f0d6067a52f9bebf820f8f3 699 SUPERFAMILY SSF54980 408 485 2.84E-24 T 12-10-2018 IPR035647 EF-G domain III/V-like VAPA_1c51000 74b277307f0d6067a52f9bebf820f8f3 699 SMART SM00889 484 603 2.8E-74 T 12-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 VAPA_1c51000 74b277307f0d6067a52f9bebf820f8f3 699 SUPERFAMILY SSF50447 254 406 2.87E-36 T 12-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily VAPA_1c51000 74b277307f0d6067a52f9bebf820f8f3 699 Gene3D G3DSA:3.40.50.300 1 297 2.5E-115 T 12-10-2018 VAPA_1c51000 74b277307f0d6067a52f9bebf820f8f3 699 PRINTS PR00315 GTP-binding elongation factor signature 58 66 4.1E-16 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 VAPA_1c51000 74b277307f0d6067a52f9bebf820f8f3 699 PRINTS PR00315 GTP-binding elongation factor signature 137 146 4.1E-16 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 VAPA_1c51000 74b277307f0d6067a52f9bebf820f8f3 699 PRINTS PR00315 GTP-binding elongation factor signature 85 95 4.1E-16 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 VAPA_1c51000 74b277307f0d6067a52f9bebf820f8f3 699 PRINTS PR00315 GTP-binding elongation factor signature 101 112 4.1E-16 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 VAPA_1c51000 74b277307f0d6067a52f9bebf820f8f3 699 PRINTS PR00315 GTP-binding elongation factor signature 12 25 4.1E-16 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 VAPA_1c51000 74b277307f0d6067a52f9bebf820f8f3 699 SUPERFAMILY SSF52540 6 286 1.1E-109 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c51000 74b277307f0d6067a52f9bebf820f8f3 699 Pfam PF14492 Elongation Factor G, domain II 408 482 3.6E-34 T 12-10-2018 VAPA_1c51000 74b277307f0d6067a52f9bebf820f8f3 699 SMART SM00838 605 693 1.3E-55 T 12-10-2018 IPR000640 Elongation factor EFG, domain V-like VAPA_1c51000 74b277307f0d6067a52f9bebf820f8f3 699 Hamap MF_00054_B Elongation factor G [fusA]. 6 697 113.438 T 12-10-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 VAPA_1c51000 74b277307f0d6067a52f9bebf820f8f3 699 TIGRFAM TIGR00484 EF-G: translation elongation factor G 1 697 0.0 T 12-10-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 VAPA_1c51000 74b277307f0d6067a52f9bebf820f8f3 699 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 12-10-2018 IPR031157 Tr-type G domain, conserved site VAPA_1c51000 74b277307f0d6067a52f9bebf820f8f3 699 Pfam PF03144 Elongation factor Tu domain 2 328 395 3.8E-17 T 12-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 VAPA_1c51000 74b277307f0d6067a52f9bebf820f8f3 699 Pfam PF00009 Elongation factor Tu GTP binding domain 9 286 5.2E-67 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 VAPA_1c51000 74b277307f0d6067a52f9bebf820f8f3 699 Gene3D G3DSA:3.30.70.870 416 485 4.9E-28 T 12-10-2018 VAPA_1c51000 74b277307f0d6067a52f9bebf820f8f3 699 SUPERFAMILY SSF54211 483 604 1.11E-45 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold VAPA_1c51000 74b277307f0d6067a52f9bebf820f8f3 699 Pfam PF03764 Elongation factor G, domain IV 483 603 3.2E-48 T 12-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 VAPA_1c51000 74b277307f0d6067a52f9bebf820f8f3 699 Pfam PF00679 Elongation factor G C-terminus 605 691 1.6E-30 T 12-10-2018 IPR000640 Elongation factor EFG, domain V-like VAPA_1c51000 74b277307f0d6067a52f9bebf820f8f3 699 Gene3D G3DSA:2.40.30.10 298 415 2.8E-49 T 12-10-2018 VAPA_1c51000 74b277307f0d6067a52f9bebf820f8f3 699 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 9 187 4.6E-35 T 12-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 VAPA_1c51000 74b277307f0d6067a52f9bebf820f8f3 699 Gene3D G3DSA:3.30.230.10 488 693 3.6E-90 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup VAPA_1c07250 c2e5e757421ae7305de64bffb1021834 194 PRINTS PR00096 Glutamine amidotransferase superfamily signature 78 89 6.1E-14 T 12-10-2018 VAPA_1c07250 c2e5e757421ae7305de64bffb1021834 194 PRINTS PR00096 Glutamine amidotransferase superfamily signature 172 185 6.1E-14 T 12-10-2018 VAPA_1c07250 c2e5e757421ae7305de64bffb1021834 194 PRINTS PR00096 Glutamine amidotransferase superfamily signature 51 60 6.1E-14 T 12-10-2018 VAPA_1c07250 c2e5e757421ae7305de64bffb1021834 194 TIGRFAM TIGR00566 trpG_papA: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase 3 193 5.4E-74 T 12-10-2018 IPR006221 Anthranilate synthase/para-aminobenzoate synthase like domain KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 VAPA_1c07250 c2e5e757421ae7305de64bffb1021834 194 Pfam PF00117 Glutamine amidotransferase class-I 5 193 3.0E-53 T 12-10-2018 IPR017926 Glutamine amidotransferase VAPA_1c07250 c2e5e757421ae7305de64bffb1021834 194 PRINTS PR00097 Anthranilate synthase component II signature 3 17 4.8E-35 T 12-10-2018 VAPA_1c07250 c2e5e757421ae7305de64bffb1021834 194 PRINTS PR00097 Anthranilate synthase component II signature 78 89 4.8E-35 T 12-10-2018 VAPA_1c07250 c2e5e757421ae7305de64bffb1021834 194 PRINTS PR00097 Anthranilate synthase component II signature 103 111 4.8E-35 T 12-10-2018 VAPA_1c07250 c2e5e757421ae7305de64bffb1021834 194 PRINTS PR00097 Anthranilate synthase component II signature 172 185 4.8E-35 T 12-10-2018 VAPA_1c07250 c2e5e757421ae7305de64bffb1021834 194 PRINTS PR00097 Anthranilate synthase component II signature 51 60 4.8E-35 T 12-10-2018 VAPA_1c07250 c2e5e757421ae7305de64bffb1021834 194 PRINTS PR00097 Anthranilate synthase component II signature 123 135 4.8E-35 T 12-10-2018 VAPA_1c07250 c2e5e757421ae7305de64bffb1021834 194 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 78 94 4.4E-5 T 12-10-2018 VAPA_1c07250 c2e5e757421ae7305de64bffb1021834 194 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 48 62 4.4E-5 T 12-10-2018 VAPA_1c07250 c2e5e757421ae7305de64bffb1021834 194 Gene3D G3DSA:3.40.50.880 1 194 1.0E-61 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like VAPA_1c07250 c2e5e757421ae7305de64bffb1021834 194 SUPERFAMILY SSF52317 1 194 8.98E-53 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like VAPA_1c43870 f132a360780847487bdf1db5b56245b2 151 Pfam PF00293 NUDIX domain 12 120 1.4E-17 T 12-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 VAPA_1c43870 f132a360780847487bdf1db5b56245b2 151 Gene3D G3DSA:3.90.79.10 4 130 6.0E-30 T 12-10-2018 VAPA_1c43870 f132a360780847487bdf1db5b56245b2 151 PRINTS PR00502 NUDIX hydrolase family signature 41 55 8.9E-10 T 12-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 VAPA_1c43870 f132a360780847487bdf1db5b56245b2 151 PRINTS PR00502 NUDIX hydrolase family signature 55 70 8.9E-10 T 12-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 VAPA_1c43870 f132a360780847487bdf1db5b56245b2 151 ProSitePatterns PS00893 Nudix box signature. 46 67 - T 12-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 VAPA_1c43870 f132a360780847487bdf1db5b56245b2 151 SUPERFAMILY SSF55811 8 115 1.06E-30 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 VAPA_1c43640 01e138358b1f5ff3f7e6145ed750eb33 285 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 188 194 - T 12-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 VAPA_1c43640 01e138358b1f5ff3f7e6145ed750eb33 285 TIGRFAM TIGR03534 RF_mod_PrmC: protein-(glutamine-N5) methyltransferase, release factor-specific 29 276 3.4E-81 T 12-10-2018 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 VAPA_1c43640 01e138358b1f5ff3f7e6145ed750eb33 285 Gene3D G3DSA:3.40.50.150 93 281 5.8E-54 T 12-10-2018 VAPA_1c43640 01e138358b1f5ff3f7e6145ed750eb33 285 Pfam PF05175 Methyltransferase small domain 112 197 3.4E-15 T 12-10-2018 IPR007848 Methyltransferase small domain GO:0008168 VAPA_1c43640 01e138358b1f5ff3f7e6145ed750eb33 285 TIGRFAM TIGR00536 hemK_fam: methyltransferase, HemK family 17 283 2.4E-70 T 12-10-2018 IPR004556 Modification methylase HemK GO:0006479|GO:0008276 VAPA_1c43640 01e138358b1f5ff3f7e6145ed750eb33 285 Gene3D G3DSA:1.10.8.10 9 92 7.7E-18 T 12-10-2018 VAPA_1c43640 01e138358b1f5ff3f7e6145ed750eb33 285 Hamap MF_02126 Release factor glutamine methyltransferase [prmC]. 11 281 41.567 T 12-10-2018 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 VAPA_1c43640 01e138358b1f5ff3f7e6145ed750eb33 285 SUPERFAMILY SSF53335 14 277 2.54E-51 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase VAPA_1c46010 3a0fc447ff93ebb40ed248a60f262776 457 SUPERFAMILY SSF55874 308 446 1.07E-32 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_1c46010 3a0fc447ff93ebb40ed248a60f262776 457 Pfam PF00672 HAMP domain 190 237 4.6E-8 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 VAPA_1c46010 3a0fc447ff93ebb40ed248a60f262776 457 Gene3D G3DSA:1.10.287.130 194 300 5.7E-17 T 12-10-2018 VAPA_1c46010 3a0fc447ff93ebb40ed248a60f262776 457 SMART SM00387 341 450 1.0E-28 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase VAPA_1c46010 3a0fc447ff93ebb40ed248a60f262776 457 SUPERFAMILY SSF47384 227 289 3.34E-9 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 VAPA_1c46010 3a0fc447ff93ebb40ed248a60f262776 457 SMART SM00388 243 301 0.0013 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 VAPA_1c46010 3a0fc447ff93ebb40ed248a60f262776 457 PRINTS PR00344 Bacterial sensor protein C-terminal signature 410 428 6.4E-10 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c46010 3a0fc447ff93ebb40ed248a60f262776 457 PRINTS PR00344 Bacterial sensor protein C-terminal signature 393 403 6.4E-10 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c46010 3a0fc447ff93ebb40ed248a60f262776 457 PRINTS PR00344 Bacterial sensor protein C-terminal signature 375 389 6.4E-10 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c46010 3a0fc447ff93ebb40ed248a60f262776 457 Gene3D G3DSA:3.30.565.10 307 453 9.4E-31 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_1c46010 3a0fc447ff93ebb40ed248a60f262776 457 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 344 446 1.9E-21 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase VAPA_1c46010 3a0fc447ff93ebb40ed248a60f262776 457 SMART SM00304 190 242 4.4E-7 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 VAPA_1c18830 ffc523582ac44f5e234f1c94626399c2 328 SUPERFAMILY SSF50129 1 140 1.67E-41 T 12-10-2018 IPR011032 GroES-like superfamily VAPA_1c18830 ffc523582ac44f5e234f1c94626399c2 328 SUPERFAMILY SSF51735 112 278 1.52E-52 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c18830 ffc523582ac44f5e234f1c94626399c2 328 Pfam PF00107 Zinc-binding dehydrogenase 151 281 4.2E-30 T 12-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 VAPA_1c18830 ffc523582ac44f5e234f1c94626399c2 328 SMART SM00829 11 326 6.9E-61 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 VAPA_1c18830 ffc523582ac44f5e234f1c94626399c2 328 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 140 161 - T 12-10-2018 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 VAPA_1c18830 ffc523582ac44f5e234f1c94626399c2 328 Gene3D G3DSA:3.40.50.720 123 271 3.9E-107 T 12-10-2018 VAPA_1c18830 ffc523582ac44f5e234f1c94626399c2 328 Gene3D G3DSA:3.90.180.10 12 322 3.9E-107 T 12-10-2018 VAPA_1c18830 ffc523582ac44f5e234f1c94626399c2 328 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 87 5.3E-12 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 VAPA_1c03320 3a55c724657ce6053568993adedd6185 333 SUPERFAMILY SSF56317 15 271 1.96E-56 T 12-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily VAPA_1c03320 3a55c724657ce6053568993adedd6185 333 Pfam PF00795 Carbon-nitrogen hydrolase 16 263 8.7E-34 T 12-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 VAPA_1c03320 3a55c724657ce6053568993adedd6185 333 Hamap MF_01243 Formamidase [amiF]. 1 329 68.72 T 12-10-2018 IPR022843 Formamidase GO:0004328|GO:0006807 KEGG: 00460+3.5.1.49|KEGG: 00630+3.5.1.49|KEGG: 00910+3.5.1.49|MetaCyc: PWY-7142 VAPA_1c03320 3a55c724657ce6053568993adedd6185 333 Gene3D G3DSA:3.60.110.10 1 302 2.3E-100 T 12-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily VAPA_1c37980 0bb6720fe72993012ee7dff10cd860a1 432 SUPERFAMILY SSF51905 15 431 3.37E-42 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c37980 0bb6720fe72993012ee7dff10cd860a1 432 SUPERFAMILY SSF54373 284 374 1.96E-11 T 12-10-2018 VAPA_1c37980 0bb6720fe72993012ee7dff10cd860a1 432 Gene3D G3DSA:3.30.9.10 149 376 4.6E-43 T 12-10-2018 VAPA_1c37980 0bb6720fe72993012ee7dff10cd860a1 432 Gene3D G3DSA:3.50.50.60 115 420 4.6E-43 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c37980 0bb6720fe72993012ee7dff10cd860a1 432 Pfam PF01266 FAD dependent oxidoreductase 15 413 1.3E-50 T 12-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 VAPA_1c37980 0bb6720fe72993012ee7dff10cd860a1 432 Gene3D G3DSA:3.50.50.60 16 67 5.4E-10 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c24940 b4fd23628156e0f9de59418d92f621c3 210 SUPERFAMILY SSF46689 13 87 2.82E-13 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 VAPA_1c24940 b4fd23628156e0f9de59418d92f621c3 210 ProSitePatterns PS01081 TetR-type HTH domain signature. 37 68 - T 12-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site VAPA_1c24940 b4fd23628156e0f9de59418d92f621c3 210 Gene3D G3DSA:1.10.357.10 11 207 1.1E-26 T 12-10-2018 VAPA_1c24940 b4fd23628156e0f9de59418d92f621c3 210 Pfam PF00440 Bacterial regulatory proteins, tetR family 27 71 7.9E-12 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 VAPA_2c08060 2c1245b2579af5ba055165723d6cee34 243 SMART SM01236 78 181 8.3E-26 T 12-10-2018 VAPA_2c08060 2c1245b2579af5ba055165723d6cee34 243 SUPERFAMILY SSF48613 9 226 9.6E-51 T 12-10-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 VAPA_2c08060 2c1245b2579af5ba055165723d6cee34 243 Pfam PF14518 Iron-containing redox enzyme 44 215 6.2E-34 T 12-10-2018 VAPA_2c08060 2c1245b2579af5ba055165723d6cee34 243 Gene3D G3DSA:1.20.910.10 2 243 2.9E-57 T 12-10-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 VAPA_2c03330 61dc1ab679d665f6c68b6600c6eac9fa 150 Gene3D G3DSA:3.40.50.620 1 144 1.9E-37 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold VAPA_2c03330 61dc1ab679d665f6c68b6600c6eac9fa 150 SUPERFAMILY SSF52402 1 146 1.93E-35 T 12-10-2018 VAPA_2c03330 61dc1ab679d665f6c68b6600c6eac9fa 150 PRINTS PR01438 Universal stress protein signature 123 145 4.7E-18 T 12-10-2018 IPR006015 Universal stress protein A VAPA_2c03330 61dc1ab679d665f6c68b6600c6eac9fa 150 PRINTS PR01438 Universal stress protein signature 2 20 4.7E-18 T 12-10-2018 IPR006015 Universal stress protein A VAPA_2c03330 61dc1ab679d665f6c68b6600c6eac9fa 150 PRINTS PR01438 Universal stress protein signature 105 117 4.7E-18 T 12-10-2018 IPR006015 Universal stress protein A VAPA_2c03330 61dc1ab679d665f6c68b6600c6eac9fa 150 Pfam PF00582 Universal stress protein family 1 145 4.2E-34 T 12-10-2018 IPR006016 UspA VAPA_2c03330 61dc1ab679d665f6c68b6600c6eac9fa 150 PIRSF PIRSF006276 1 147 1.3E-19 T 12-10-2018 IPR006015 Universal stress protein A VAPA_2c04190 fdb4d0847b15e04a70a1273291ee68d3 662 Gene3D G3DSA:3.40.1660.10 249 641 9.1E-71 T 12-10-2018 VAPA_2c04190 fdb4d0847b15e04a70a1273291ee68d3 662 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 12 210 2.3E-41 T 12-10-2018 VAPA_2c04190 fdb4d0847b15e04a70a1273291ee68d3 662 Gene3D G3DSA:3.40.50.150 3 218 3.3E-55 T 12-10-2018 VAPA_2c04190 fdb4d0847b15e04a70a1273291ee68d3 662 Gene3D G3DSA:3.30.1870.10 292 369 9.1E-71 T 12-10-2018 VAPA_2c04190 fdb4d0847b15e04a70a1273291ee68d3 662 Gene3D G3DSA:1.20.1440.30 370 500 9.1E-71 T 12-10-2018 VAPA_2c04190 fdb4d0847b15e04a70a1273291ee68d3 662 Pfam PF05139 Erythromycin esterase 290 640 1.1E-121 T 12-10-2018 IPR007815 Erythromycin esterase GO:0046677 VAPA_2c04190 fdb4d0847b15e04a70a1273291ee68d3 662 SUPERFAMILY SSF159501 238 646 1.5E-136 T 12-10-2018 VAPA_2c04190 fdb4d0847b15e04a70a1273291ee68d3 662 SUPERFAMILY SSF53335 4 197 1.86E-42 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase VAPA_2c04190 fdb4d0847b15e04a70a1273291ee68d3 662 PIRSF PIRSF036794 229 650 1.5E-122 T 12-10-2018 IPR014622 Uncharacterised conserved protein UCP036794, erythromycin esterase-type VAPA_2c09360 06236cc498de48420851334ca88cf1ea 302 SUPERFAMILY SSF53850 89 296 1.07E-48 T 12-10-2018 VAPA_2c09360 06236cc498de48420851334ca88cf1ea 302 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 62 9.1E-16 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_2c09360 06236cc498de48420851334ca88cf1ea 302 Gene3D G3DSA:3.40.190.290 91 296 8.8E-71 T 12-10-2018 VAPA_2c09360 06236cc498de48420851334ca88cf1ea 302 Gene3D G3DSA:1.10.10.10 3 89 4.8E-26 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_2c09360 06236cc498de48420851334ca88cf1ea 302 Pfam PF03466 LysR substrate binding domain 88 293 1.5E-44 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_2c09360 06236cc498de48420851334ca88cf1ea 302 SUPERFAMILY SSF46785 6 88 7.71E-20 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c03960 3f62c9fc3fd2618699a451521bc662c7 407 Pfam PF04286 Protein of unknown function (DUF445) 36 404 6.3E-99 T 12-10-2018 IPR007383 Protein of unknown function DUF445 VAPA_1c36270 c7f3d58e1a6a7e7264bd1eb58a072ba4 123 Pfam PF00011 Hsp20/alpha crystallin family 39 116 8.8E-12 T 12-10-2018 IPR002068 Alpha crystallin/Hsp20 domain VAPA_1c36270 c7f3d58e1a6a7e7264bd1eb58a072ba4 123 Gene3D G3DSA:2.60.40.790 15 123 2.8E-16 T 12-10-2018 IPR008978 HSP20-like chaperone VAPA_1c36270 c7f3d58e1a6a7e7264bd1eb58a072ba4 123 SUPERFAMILY SSF49764 10 113 1.15E-15 T 12-10-2018 IPR008978 HSP20-like chaperone VAPA_1c39770 618b00d73a6484ac786d3690829eb175 492 Gene3D G3DSA:3.40.640.10 121 481 1.8E-112 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 VAPA_1c39770 618b00d73a6484ac786d3690829eb175 492 SUPERFAMILY SSF46785 24 93 2.73E-16 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c39770 618b00d73a6484ac786d3690829eb175 492 Gene3D G3DSA:1.10.10.10 14 95 1.1E-17 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c39770 618b00d73a6484ac786d3690829eb175 492 SUPERFAMILY SSF53383 130 487 3.94E-79 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase VAPA_1c39770 618b00d73a6484ac786d3690829eb175 492 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 50 64 2.5E-6 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_1c39770 618b00d73a6484ac786d3690829eb175 492 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 64 80 2.5E-6 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_1c39770 618b00d73a6484ac786d3690829eb175 492 Pfam PF00392 Bacterial regulatory proteins, gntR family 29 88 1.1E-12 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_1c39770 618b00d73a6484ac786d3690829eb175 492 SMART SM00345 31 89 1.1E-9 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_1c39770 618b00d73a6484ac786d3690829eb175 492 Pfam PF00155 Aminotransferase class I and II 145 406 2.4E-18 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 VAPA_2c02640 5c03ad4d9a8509faef227aaf76ecdb4c 292 Gene3D G3DSA:3.40.630.30 1 135 8.3E-20 T 12-10-2018 VAPA_2c02640 5c03ad4d9a8509faef227aaf76ecdb4c 292 Pfam PF13673 Acetyltransferase (GNAT) domain 53 137 8.0E-11 T 12-10-2018 IPR000182 GNAT domain VAPA_2c02640 5c03ad4d9a8509faef227aaf76ecdb4c 292 SUPERFAMILY SSF55729 13 270 4.29E-42 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase VAPA_1c00680 0b080345efdf173690db574d168285a1 140 Pfam PF03061 Thioesterase superfamily 51 127 6.3E-16 T 12-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 VAPA_1c00680 0b080345efdf173690db574d168285a1 140 SUPERFAMILY SSF54637 16 138 1.18E-31 T 12-10-2018 IPR029069 HotDog domain superfamily VAPA_1c00680 0b080345efdf173690db574d168285a1 140 Gene3D G3DSA:3.10.129.10 1 139 1.7E-55 T 12-10-2018 VAPA_1c00680 0b080345efdf173690db574d168285a1 140 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 21 135 4.8E-37 T 12-10-2018 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-77289 VAPA_2c04050 831747b2d50c9bec35344c5bcbcf04c2 139 Pfam PF09086 Domain of unknown function (DUF1924) 45 134 4.9E-38 T 12-10-2018 IPR015170 Protein of unknown function DUF1924 VAPA_2c04050 831747b2d50c9bec35344c5bcbcf04c2 139 SUPERFAMILY SSF46626 33 136 1.8E-33 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 VAPA_2c04050 831747b2d50c9bec35344c5bcbcf04c2 139 Gene3D G3DSA:1.10.760.10 31 139 7.4E-41 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 VAPA_1c05450 1a608b6c7f7ff92f1514333c9a29db37 264 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 238 259 3.0E-7 T 12-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal VAPA_1c05450 1a608b6c7f7ff92f1514333c9a29db37 264 ProSitePatterns PS00211 ABC transporters family signature. 161 175 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_1c05450 1a608b6c7f7ff92f1514333c9a29db37 264 SUPERFAMILY SSF52540 18 260 2.83E-65 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c05450 1a608b6c7f7ff92f1514333c9a29db37 264 Gene3D G3DSA:3.40.50.300 16 264 4.0E-73 T 12-10-2018 VAPA_1c05450 1a608b6c7f7ff92f1514333c9a29db37 264 SMART SM00382 42 245 1.3E-9 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c05450 1a608b6c7f7ff92f1514333c9a29db37 264 TIGRFAM TIGR04406 LPS_export_lptB: LPS export ABC transporter ATP-binding protein 18 264 6.7E-117 T 12-10-2018 IPR030921 LPS export ABC transporter, ATP-binding protein LptB GO:0043190|GO:0055085 VAPA_1c05450 1a608b6c7f7ff92f1514333c9a29db37 264 Pfam PF00005 ABC transporter 34 189 4.0E-35 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c49630 17f307973b3917ab92b4ff2e6c9f8ad2 257 Gene3D G3DSA:3.40.50.1820 32 249 2.6E-31 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c49630 17f307973b3917ab92b4ff2e6c9f8ad2 257 Pfam PF12697 Alpha/beta hydrolase family 49 210 7.7E-6 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 VAPA_1c49630 17f307973b3917ab92b4ff2e6c9f8ad2 257 SUPERFAMILY SSF53474 41 226 5.99E-25 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c24080 9cc76684c58e22bcb172681ccbc1b890 303 SUPERFAMILY SSF89796 19 298 4.19E-54 T 12-10-2018 IPR023606 CoA-transferase family III domain superfamily VAPA_1c24080 9cc76684c58e22bcb172681ccbc1b890 303 Pfam PF02515 CoA-transferase family III 23 298 1.3E-39 T 12-10-2018 IPR003673 CoA-transferase family III GO:0003824 VAPA_1c24080 9cc76684c58e22bcb172681ccbc1b890 303 Gene3D G3DSA:3.40.50.10540 15 227 3.1E-34 T 12-10-2018 IPR023606 CoA-transferase family III domain superfamily VAPA_1c24080 9cc76684c58e22bcb172681ccbc1b890 303 Gene3D G3DSA:3.30.1540.10 228 300 2.6E-12 T 12-10-2018 VAPA_1c51130 c15acb763ef5db77d07b8d87dabb0f8d 203 PIRSF PIRSF006386 3 203 1.8E-50 T 12-10-2018 IPR014440 HCCA isomerase/glutathione S-transferase kappa Reactome: R-HSA-156590|Reactome: R-HSA-9033241 VAPA_1c51130 c15acb763ef5db77d07b8d87dabb0f8d 203 Gene3D G3DSA:3.40.30.10 8 203 1.7E-53 T 12-10-2018 VAPA_1c51130 c15acb763ef5db77d07b8d87dabb0f8d 203 Pfam PF01323 DSBA-like thioredoxin domain 8 201 3.0E-35 T 12-10-2018 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590|Reactome: R-HSA-9033241 VAPA_1c51130 c15acb763ef5db77d07b8d87dabb0f8d 203 SUPERFAMILY SSF52833 5 202 3.23E-43 T 12-10-2018 IPR036249 Thioredoxin-like superfamily VAPA_1c09910 b540a1239f529c351863a4dd0e10b87e 245 Gene3D G3DSA:3.40.50.2300 19 116 1.8E-13 T 12-10-2018 VAPA_1c09910 b540a1239f529c351863a4dd0e10b87e 245 Gene3D G3DSA:1.10.10.10 117 245 2.7E-29 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c09910 b540a1239f529c351863a4dd0e10b87e 245 Pfam PF00196 Bacterial regulatory proteins, luxR family 180 232 3.2E-15 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_1c09910 b540a1239f529c351863a4dd0e10b87e 245 SUPERFAMILY SSF52172 18 150 1.99E-23 T 12-10-2018 IPR011006 CheY-like superfamily VAPA_1c09910 b540a1239f529c351863a4dd0e10b87e 245 Pfam PF00072 Response regulator receiver domain 20 133 1.4E-15 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_1c09910 b540a1239f529c351863a4dd0e10b87e 245 SMART SM00448 18 133 9.6E-16 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_1c09910 b540a1239f529c351863a4dd0e10b87e 245 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 181 195 3.2E-10 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_1c09910 b540a1239f529c351863a4dd0e10b87e 245 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 211 223 3.2E-10 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_1c09910 b540a1239f529c351863a4dd0e10b87e 245 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 195 211 3.2E-10 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_1c09910 b540a1239f529c351863a4dd0e10b87e 245 SUPERFAMILY SSF46894 167 242 5.44E-20 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 VAPA_1c09910 b540a1239f529c351863a4dd0e10b87e 245 SMART SM00421 178 235 1.3E-18 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_1c53700 a85c1f360d76f31843e16ea865a860b8 159 SUPERFAMILY SSF54523 21 138 2.88E-24 T 12-10-2018 VAPA_1c53700 a85c1f360d76f31843e16ea865a860b8 159 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 19 39 - T 12-10-2018 IPR012902 Prokaryotic N-terminal methylation site VAPA_1c53700 a85c1f360d76f31843e16ea865a860b8 159 PRINTS PR00813 Bacterial general secretion pathway protein G signature 56 74 2.4E-11 T 12-10-2018 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 VAPA_1c53700 a85c1f360d76f31843e16ea865a860b8 159 PRINTS PR00813 Bacterial general secretion pathway protein G signature 20 45 2.4E-11 T 12-10-2018 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 VAPA_1c53700 a85c1f360d76f31843e16ea865a860b8 159 Pfam PF07963 Prokaryotic N-terminal methylation motif 18 40 2.4E-8 T 12-10-2018 IPR012902 Prokaryotic N-terminal methylation site VAPA_1c53700 a85c1f360d76f31843e16ea865a860b8 159 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 19 41 4.0E-9 T 12-10-2018 IPR012902 Prokaryotic N-terminal methylation site VAPA_1c53700 a85c1f360d76f31843e16ea865a860b8 159 Gene3D G3DSA:3.30.700.10 21 159 4.5E-30 T 12-10-2018 VAPA_1c53700 a85c1f360d76f31843e16ea865a860b8 159 Pfam PF16732 Type IV minor pilin ComP, DNA uptake sequence receptor 42 124 2.6E-11 T 12-10-2018 IPR031982 Type IV minor pilin ComP VAPA_2c11410 c223ad845d558f9f15705c05710e9370 234 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_2c11410 c223ad845d558f9f15705c05710e9370 234 SMART SM00382 26 210 2.9E-12 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_2c11410 c223ad845d558f9f15705c05710e9370 234 Gene3D G3DSA:3.40.50.300 1 232 2.4E-61 T 12-10-2018 VAPA_2c11410 c223ad845d558f9f15705c05710e9370 234 Pfam PF00005 ABC transporter 17 160 3.0E-32 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_2c11410 c223ad845d558f9f15705c05710e9370 234 SUPERFAMILY SSF52540 1 220 2.61E-59 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c22920 7ecd5458e32eebcb852bedf23eaa3530 292 SUPERFAMILY SSF51197 3 282 6.41E-70 T 12-10-2018 VAPA_1c22920 7ecd5458e32eebcb852bedf23eaa3530 292 Pfam PF02668 Taurine catabolism dioxygenase TauD, TfdA family 5 280 3.0E-58 T 12-10-2018 IPR003819 TauD/TfdA-like domain GO:0016491|GO:0055114 Reactome: R-HSA-71262 VAPA_1c22920 7ecd5458e32eebcb852bedf23eaa3530 292 Gene3D G3DSA:3.60.130.10 1 289 4.8E-76 T 12-10-2018 VAPA_2c07330 96cc9f2a5bd11b2f5706df94d98ecc80 331 SUPERFAMILY SSF50891 196 300 4.55E-12 T 12-10-2018 IPR029000 Cyclophilin-like domain superfamily VAPA_2c07330 96cc9f2a5bd11b2f5706df94d98ecc80 331 Pfam PF02626 Carboxyltransferase domain, subdomain A and B 24 292 7.8E-83 T 12-10-2018 IPR003778 Carboxyltransferase domain, subdomain A and B VAPA_2c07330 96cc9f2a5bd11b2f5706df94d98ecc80 331 SMART SM00797 23 310 6.6E-133 T 12-10-2018 IPR003778 Carboxyltransferase domain, subdomain A and B VAPA_2c07330 96cc9f2a5bd11b2f5706df94d98ecc80 331 TIGRFAM TIGR00724 urea_amlyse_rel: biotin-dependent carboxylase uncharacterized domain 1 318 3.1E-92 T 12-10-2018 IPR003778 Carboxyltransferase domain, subdomain A and B VAPA_2c07330 96cc9f2a5bd11b2f5706df94d98ecc80 331 Gene3D G3DSA:2.40.100.10 183 321 2.0E-44 T 12-10-2018 IPR029000 Cyclophilin-like domain superfamily VAPA_2c10850 bb9b639b7094ba23bf59224ab7ff39d5 322 SUPERFAMILY SSF46785 16 98 3.63E-19 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_2c10850 bb9b639b7094ba23bf59224ab7ff39d5 322 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 17 76 7.7E-15 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_2c10850 bb9b639b7094ba23bf59224ab7ff39d5 322 SUPERFAMILY SSF53850 103 310 7.91E-31 T 12-10-2018 VAPA_2c10850 bb9b639b7094ba23bf59224ab7ff39d5 322 Gene3D G3DSA:1.10.10.10 16 102 2.9E-20 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_2c10850 bb9b639b7094ba23bf59224ab7ff39d5 322 Gene3D G3DSA:3.40.190.290 105 312 1.7E-34 T 12-10-2018 VAPA_2c10850 bb9b639b7094ba23bf59224ab7ff39d5 322 Pfam PF03466 LysR substrate binding domain 101 302 3.2E-31 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_1c19860 7932c9a7a4c988610386782be72b3024 130 SUPERFAMILY SSF103481 6 90 2.62E-9 T 12-10-2018 VAPA_1c23620 3fe7dce7f52e6aa384bf6706af934e2d 606 Pfam PF00849 RNA pseudouridylate synthase 264 396 2.1E-14 T 12-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 VAPA_1c23620 3fe7dce7f52e6aa384bf6706af934e2d 606 SMART SM00363 201 258 1.2E-6 T 12-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VAPA_1c23620 3fe7dce7f52e6aa384bf6706af934e2d 606 SUPERFAMILY SSF55174 203 289 1.96E-14 T 12-10-2018 VAPA_1c23620 3fe7dce7f52e6aa384bf6706af934e2d 606 Pfam PF01479 S4 domain 203 246 1.2E-6 T 12-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VAPA_1c23620 3fe7dce7f52e6aa384bf6706af934e2d 606 SUPERFAMILY SSF55120 262 433 1.92E-39 T 12-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 VAPA_1c23620 3fe7dce7f52e6aa384bf6706af934e2d 606 Gene3D G3DSA:3.30.70.1560 332 409 7.4E-46 T 12-10-2018 VAPA_1c23620 3fe7dce7f52e6aa384bf6706af934e2d 606 Gene3D G3DSA:3.30.70.580 265 431 7.4E-46 T 12-10-2018 VAPA_1c23620 3fe7dce7f52e6aa384bf6706af934e2d 606 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 268 428 6.1E-49 T 12-10-2018 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 VAPA_1c23620 3fe7dce7f52e6aa384bf6706af934e2d 606 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 302 316 - T 12-10-2018 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 VAPA_1c23620 3fe7dce7f52e6aa384bf6706af934e2d 606 Gene3D G3DSA:3.10.290.10 196 257 2.8E-17 T 12-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 VAPA_1c06590 39f3148d71f60ab8157cb993add3dd48 334 PIRSF PIRSF017082 7 333 5.3E-75 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c06590 39f3148d71f60ab8157cb993add3dd48 334 SUPERFAMILY SSF53850 95 292 2.71E-10 T 12-10-2018 VAPA_1c06590 39f3148d71f60ab8157cb993add3dd48 334 Gene3D G3DSA:3.40.190.10 136 259 1.5E-117 T 12-10-2018 VAPA_1c06590 39f3148d71f60ab8157cb993add3dd48 334 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 58 329 5.8E-87 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c06590 39f3148d71f60ab8157cb993add3dd48 334 Gene3D G3DSA:3.40.190.150 39 324 1.5E-117 T 12-10-2018 VAPA_1c06410 27295eaaa361512571bb4bd203bdb2a6 149 Pfam PF08964 Beta/Gamma crystallin 57 113 1.3E-6 T 12-10-2018 IPR015059 Calcium-dependent cell adhesion molecule, N-terminal GO:0016020|GO:0098609 VAPA_1c06410 27295eaaa361512571bb4bd203bdb2a6 149 SUPERFAMILY SSF49695 56 124 2.56E-5 T 12-10-2018 IPR011024 Gamma-crystallin-like VAPA_1c06410 27295eaaa361512571bb4bd203bdb2a6 149 Gene3D G3DSA:2.60.20.10 37 149 3.7E-25 T 12-10-2018 VAPA_1c41590 e9022993a5b5917bf164b7a5f857a60c 407 Pfam PF02653 Branched-chain amino acid transport system / permease component 53 347 2.2E-39 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 VAPA_1c41590 e9022993a5b5917bf164b7a5f857a60c 407 TIGRFAM TIGR03408 urea_trans_UrtC: urea ABC transporter, permease protein UrtC 44 358 1.2E-137 T 12-10-2018 IPR017778 ABC transporter, urea, permease protein, UrtC VAPA_1c36020 43889bd582947648f8a1d57b3a248217 158 PIRSF PIRSF032131 1 155 1.1E-45 T 12-10-2018 IPR009562 Protein of unknown function DUF1178 VAPA_1c36020 43889bd582947648f8a1d57b3a248217 158 Pfam PF06676 Protein of unknown function (DUF1178) 1 150 2.2E-53 T 12-10-2018 IPR009562 Protein of unknown function DUF1178 VAPA_1c47880 0868665a9cf9d18d682f38f6ab8540e7 240 SUPERFAMILY SSF52833 83 234 1.0E-32 T 12-10-2018 IPR036249 Thioredoxin-like superfamily VAPA_1c47880 0868665a9cf9d18d682f38f6ab8540e7 240 Pfam PF10411 Disulfide bond isomerase protein N-terminus 28 82 1.7E-19 T 12-10-2018 IPR018950 Disulphide bond isomerase, DsbC/G, N-terminal VAPA_1c47880 0868665a9cf9d18d682f38f6ab8540e7 240 Gene3D G3DSA:3.40.30.10 108 238 1.1E-37 T 12-10-2018 VAPA_1c47880 0868665a9cf9d18d682f38f6ab8540e7 240 SUPERFAMILY SSF54423 25 83 1.08E-10 T 12-10-2018 IPR009094 Disulphide bond isomerase DsbC/G, N-terminal domain superfamily GO:0042597 VAPA_1c47880 0868665a9cf9d18d682f38f6ab8540e7 240 Gene3D G3DSA:3.10.450.70 21 86 6.5E-10 T 12-10-2018 IPR009094 Disulphide bond isomerase DsbC/G, N-terminal domain superfamily GO:0042597 VAPA_1c47880 0868665a9cf9d18d682f38f6ab8540e7 240 Pfam PF13098 Thioredoxin-like domain 112 235 3.3E-34 T 12-10-2018 IPR012336 Thioredoxin-like fold VAPA_1c47880 0868665a9cf9d18d682f38f6ab8540e7 240 ProSitePatterns PS00194 Thioredoxin family active site. 119 137 - T 12-10-2018 IPR017937 Thioredoxin, conserved site GO:0045454 VAPA_1c40810 b8fb571104ed03e047a9de1d8da67557 285 Gene3D G3DSA:3.20.20.100 1 285 1.1E-91 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily VAPA_1c40810 b8fb571104ed03e047a9de1d8da67557 285 PRINTS PR00069 Aldo-keto reductase signature 132 149 3.8E-15 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 VAPA_1c40810 b8fb571104ed03e047a9de1d8da67557 285 PRINTS PR00069 Aldo-keto reductase signature 39 63 3.8E-15 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 VAPA_1c40810 b8fb571104ed03e047a9de1d8da67557 285 PRINTS PR00069 Aldo-keto reductase signature 207 231 3.8E-15 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 VAPA_1c40810 b8fb571104ed03e047a9de1d8da67557 285 PRINTS PR00069 Aldo-keto reductase signature 102 120 3.8E-15 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 VAPA_1c40810 b8fb571104ed03e047a9de1d8da67557 285 PIRSF PIRSF000097 120 284 6.1E-13 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 VAPA_1c40810 b8fb571104ed03e047a9de1d8da67557 285 PIRSF PIRSF000097 1 123 1.4E-30 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 VAPA_1c40810 b8fb571104ed03e047a9de1d8da67557 285 Pfam PF00248 Aldo/keto reductase family 15 272 6.3E-51 T 12-10-2018 IPR023210 NADP-dependent oxidoreductase domain VAPA_1c40810 b8fb571104ed03e047a9de1d8da67557 285 SUPERFAMILY SSF51430 6 278 1.31E-80 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily VAPA_1c03500 7152f6f0759e8aa913dc82ef814de9cd 422 SUPERFAMILY SSF56529 119 421 1.57E-90 T 12-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 VAPA_1c03500 7152f6f0759e8aa913dc82ef814de9cd 422 Gene3D G3DSA:3.90.850.10 115 422 1.2E-111 T 12-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 VAPA_1c03500 7152f6f0759e8aa913dc82ef814de9cd 422 Gene3D G3DSA:2.30.30.230 1 114 2.0E-24 T 12-10-2018 IPR036462 Fumarylacetoacetase, N-terminal domain superfamily GO:0004334|GO:0009072 KEGG: 00350+3.7.1.2|KEGG: 00643+3.7.1.2|Reactome: R-HSA-71182 VAPA_1c03500 7152f6f0759e8aa913dc82ef814de9cd 422 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 123 421 7.1E-53 T 12-10-2018 IPR011234 Fumarylacetoacetase-like, C-terminal GO:0003824 VAPA_1c03500 7152f6f0759e8aa913dc82ef814de9cd 422 Pfam PF09298 Fumarylacetoacetase N-terminal 30 117 2.1E-13 T 12-10-2018 IPR015377 Fumarylacetoacetase, N-terminal GO:0004334|GO:0009072 KEGG: 00350+3.7.1.2|KEGG: 00643+3.7.1.2|Reactome: R-HSA-71182 VAPA_1c03500 7152f6f0759e8aa913dc82ef814de9cd 422 TIGRFAM TIGR01266 fum_ac_acetase: fumarylacetoacetase 15 421 2.8E-152 T 12-10-2018 IPR005959 Fumarylacetoacetase GO:0004334|GO:0009072 KEGG: 00350+3.7.1.2|KEGG: 00643+3.7.1.2|Reactome: R-HSA-71182 VAPA_1c03500 7152f6f0759e8aa913dc82ef814de9cd 422 SUPERFAMILY SSF63433 14 117 3.01E-25 T 12-10-2018 IPR036462 Fumarylacetoacetase, N-terminal domain superfamily GO:0004334|GO:0009072 KEGG: 00350+3.7.1.2|KEGG: 00643+3.7.1.2|Reactome: R-HSA-71182 VAPA_1c05200 ef868b7be5495b0aa2c0f4d3287ff824 418 Hamap MF_01978 Pyrophosphate--fructose 6-phosphate 1-phosphotransferase [pfp]. 3 397 42.79 T 12-10-2018 IPR011404 Pyrophosphate--fructose 6-phosphate 1-phosphotransferase, XF0274 GO:0006096|GO:0047334 KEGG: 00010+2.7.1.90|KEGG: 00030+2.7.1.90|KEGG: 00051+2.7.1.90|MetaCyc: PWY-1042 VAPA_1c05200 ef868b7be5495b0aa2c0f4d3287ff824 418 SUPERFAMILY SSF53784 4 413 4.45E-104 T 12-10-2018 IPR035966 Phosphofructokinase superfamily GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 VAPA_1c05200 ef868b7be5495b0aa2c0f4d3287ff824 418 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 8 27 5.8E-9 T 12-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 VAPA_1c05200 ef868b7be5495b0aa2c0f4d3287ff824 418 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 256 278 5.8E-9 T 12-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 VAPA_1c05200 ef868b7be5495b0aa2c0f4d3287ff824 418 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 179 195 5.8E-9 T 12-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 VAPA_1c05200 ef868b7be5495b0aa2c0f4d3287ff824 418 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 137 154 5.8E-9 T 12-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 VAPA_1c05200 ef868b7be5495b0aa2c0f4d3287ff824 418 Gene3D G3DSA:3.40.50.450 5 398 2.8E-145 T 12-10-2018 VAPA_1c05200 ef868b7be5495b0aa2c0f4d3287ff824 418 Pfam PF00365 Phosphofructokinase 10 322 1.8E-44 T 12-10-2018 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 VAPA_1c05200 ef868b7be5495b0aa2c0f4d3287ff824 418 PIRSF PIRSF036483 3 416 1.1E-193 T 12-10-2018 IPR011404 Pyrophosphate--fructose 6-phosphate 1-phosphotransferase, XF0274 GO:0006096|GO:0047334 KEGG: 00010+2.7.1.90|KEGG: 00030+2.7.1.90|KEGG: 00051+2.7.1.90|MetaCyc: PWY-1042 VAPA_1c05200 ef868b7be5495b0aa2c0f4d3287ff824 418 Gene3D G3DSA:3.40.50.460 142 385 2.8E-145 T 12-10-2018 VAPA_1c02330 90934d8955f182d71f8100dd6d8d2c79 623 PIRSF PIRSF028304 1 623 6.0E-190 T 12-10-2018 IPR010272 Type VI secretion system, TssF-like VAPA_1c02330 90934d8955f182d71f8100dd6d8d2c79 623 TIGRFAM TIGR03359 VI_chp_6: type VI secretion protein, TIGR03359 family 5 622 5.1E-194 T 12-10-2018 IPR010272 Type VI secretion system, TssF-like VAPA_1c02330 90934d8955f182d71f8100dd6d8d2c79 623 Pfam PF05947 Type VI secretion system, TssF 6 621 3.3E-219 T 12-10-2018 IPR010272 Type VI secretion system, TssF-like VAPA_1c19220 92fc4a3bef2a70061a50a1f199bca3a2 158 Pfam PF02391 MoaE protein 9 122 7.9E-35 T 12-10-2018 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 VAPA_1c19220 92fc4a3bef2a70061a50a1f199bca3a2 158 Gene3D G3DSA:3.90.1170.40 1 151 2.1E-47 T 12-10-2018 IPR036563 Molybdopterin biosynthesis MoaE subunit superfamily GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 VAPA_1c19220 92fc4a3bef2a70061a50a1f199bca3a2 158 SUPERFAMILY SSF54690 5 151 4.84E-50 T 12-10-2018 IPR036563 Molybdopterin biosynthesis MoaE subunit superfamily GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 VAPA_1c26790 559c9d7b5476a29164b1172936daee8c 284 Gene3D G3DSA:3.40.190.10 48 269 4.3E-27 T 12-10-2018 VAPA_1c26790 559c9d7b5476a29164b1172936daee8c 284 SUPERFAMILY SSF53850 18 268 1.3E-25 T 12-10-2018 VAPA_1c26790 559c9d7b5476a29164b1172936daee8c 284 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 52 269 1.6E-19 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF VAPA_1c26790 559c9d7b5476a29164b1172936daee8c 284 SMART SM00062 51 280 0.0011 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF VAPA_1c26790 559c9d7b5476a29164b1172936daee8c 284 Gene3D G3DSA:3.40.190.10 139 243 4.3E-27 T 12-10-2018 VAPA_2c10230 94d801f8800c8945f48f55da212c5570 423 Gene3D G3DSA:2.60.40.1610 60 200 1.2E-9 T 12-10-2018 IPR037050 Domain of unknown function DUF1254 superfamily VAPA_2c10230 94d801f8800c8945f48f55da212c5570 423 Pfam PF06863 Protein of unknown function (DUF1254) 56 186 9.5E-45 T 12-10-2018 IPR010679 Domain of unknown function DUF1254 VAPA_2c10230 94d801f8800c8945f48f55da212c5570 423 Gene3D G3DSA:2.60.120.600 269 423 7.1E-35 T 12-10-2018 IPR037049 Domain of unknown function DUF1214, C-terminal domain superfamily VAPA_2c10230 94d801f8800c8945f48f55da212c5570 423 Pfam PF06742 Protein of unknown function (DUF1214) 299 407 1.2E-32 T 12-10-2018 IPR010621 Domain of unknown function DUF1214 VAPA_2c10230 94d801f8800c8945f48f55da212c5570 423 SUPERFAMILY SSF160935 18 423 1.7E-97 T 12-10-2018 VAPA_2c09040 0a294ba5541a9e7d135560f340ea75eb 299 SUPERFAMILY SSF47616 78 197 1.35E-22 T 12-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily VAPA_2c09040 0a294ba5541a9e7d135560f340ea75eb 299 Gene3D G3DSA:3.40.30.10 2 197 4.2E-68 T 12-10-2018 VAPA_2c09040 0a294ba5541a9e7d135560f340ea75eb 299 Pfam PF02798 Glutathione S-transferase, N-terminal domain 1 70 8.4E-11 T 12-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 VAPA_2c09040 0a294ba5541a9e7d135560f340ea75eb 299 Pfam PF00043 Glutathione S-transferase, C-terminal domain 114 189 4.9E-6 T 12-10-2018 IPR004046 Glutathione S-transferase, C-terminal VAPA_2c09040 0a294ba5541a9e7d135560f340ea75eb 299 Gene3D G3DSA:1.20.1050.10 79 190 4.2E-68 T 12-10-2018 VAPA_2c09040 0a294ba5541a9e7d135560f340ea75eb 299 SUPERFAMILY SSF52833 1 78 2.51E-18 T 12-10-2018 IPR036249 Thioredoxin-like superfamily VAPA_1c17590 7676ed5c69f9a592f28c23787fe20233 403 Hamap MF_00672 UPF0761 membrane protein YihY [yihY]. 5 307 21.39 T 12-10-2018 IPR023679 Uncharacterised protein family UPF0761, bacterial VAPA_1c17590 7676ed5c69f9a592f28c23787fe20233 403 Pfam PF03631 Virulence factor BrkB 32 276 3.6E-54 T 12-10-2018 IPR017039 Virulence factor BrkB VAPA_1c17590 7676ed5c69f9a592f28c23787fe20233 403 TIGRFAM TIGR00765 yihY_not_rbn: YihY family inner membrane protein 26 276 2.4E-58 T 12-10-2018 IPR017039 Virulence factor BrkB VAPA_2c13050 035ea96ace094bab4825c9c686f781f9 106 Gene3D G3DSA:1.10.260.40 13 91 5.3E-17 T 12-10-2018 VAPA_2c13050 035ea96ace094bab4825c9c686f781f9 106 Pfam PF13560 Helix-turn-helix domain 24 82 2.7E-13 T 12-10-2018 VAPA_2c13050 035ea96ace094bab4825c9c686f781f9 106 SUPERFAMILY SSF47413 23 88 4.79E-16 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 VAPA_2c13050 035ea96ace094bab4825c9c686f781f9 106 SMART SM00530 28 83 7.6E-12 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 VAPA_1c01580 25c4e7e34e693cb79a5ed7b37d6aa5c4 312 SUPERFAMILY SSF53850 92 294 5.43E-37 T 12-10-2018 VAPA_1c01580 25c4e7e34e693cb79a5ed7b37d6aa5c4 312 Gene3D G3DSA:1.10.10.10 8 90 5.0E-16 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c01580 25c4e7e34e693cb79a5ed7b37d6aa5c4 312 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 23 34 1.1E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c01580 25c4e7e34e693cb79a5ed7b37d6aa5c4 312 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 44 1.1E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c01580 25c4e7e34e693cb79a5ed7b37d6aa5c4 312 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 44 55 1.1E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c01580 25c4e7e34e693cb79a5ed7b37d6aa5c4 312 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 9 65 5.2E-17 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c01580 25c4e7e34e693cb79a5ed7b37d6aa5c4 312 Gene3D G3DSA:3.40.190.290 96 290 2.4E-38 T 12-10-2018 VAPA_1c01580 25c4e7e34e693cb79a5ed7b37d6aa5c4 312 SUPERFAMILY SSF46785 4 116 1.59E-20 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c01580 25c4e7e34e693cb79a5ed7b37d6aa5c4 312 Pfam PF03466 LysR substrate binding domain 92 290 1.6E-31 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_1c29110 c97922aecbc9d0104ecf7bc79978a9a4 346 Pfam PF02606 Tetraacyldisaccharide-1-P 4'-kinase 33 337 1.3E-94 T 12-10-2018 IPR003758 Tetraacyldisaccharide 4'-kinase GO:0005524|GO:0009029|GO:0009245 KEGG: 00540+2.7.1.130 VAPA_1c29110 c97922aecbc9d0104ecf7bc79978a9a4 346 SUPERFAMILY SSF52540 65 209 2.87E-12 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c29110 c97922aecbc9d0104ecf7bc79978a9a4 346 TIGRFAM TIGR00682 lpxK: tetraacyldisaccharide 4'-kinase 40 310 2.9E-59 T 12-10-2018 IPR003758 Tetraacyldisaccharide 4'-kinase GO:0005524|GO:0009029|GO:0009245 KEGG: 00540+2.7.1.130 VAPA_1c29110 c97922aecbc9d0104ecf7bc79978a9a4 346 Hamap MF_00409 Tetraacyldisaccharide 4'-kinase [lpxK]. 21 338 34.018 T 12-10-2018 IPR003758 Tetraacyldisaccharide 4'-kinase GO:0005524|GO:0009029|GO:0009245 KEGG: 00540+2.7.1.130 VAPA_2c10390 333197e9acbd5a0ca21338de9917b3dd 295 Pfam PF00775 Dioxygenase 100 283 1.5E-43 T 12-10-2018 IPR000627 Intradiol ring-cleavage dioxygenase, C-terminal GO:0003824|GO:0006725|GO:0008199|GO:0055114 VAPA_2c10390 333197e9acbd5a0ca21338de9917b3dd 295 SUPERFAMILY SSF49482 1 285 2.22E-94 T 12-10-2018 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 VAPA_2c10390 333197e9acbd5a0ca21338de9917b3dd 295 Gene3D G3DSA:2.60.130.10 1 285 3.1E-117 T 12-10-2018 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 VAPA_2c10390 333197e9acbd5a0ca21338de9917b3dd 295 Pfam PF04444 Catechol dioxygenase N terminus 22 95 9.1E-31 T 12-10-2018 IPR007535 Catechol dioxygenase, N-terminal GO:0005506|GO:0009712|GO:0018576|GO:0055114 VAPA_1c38070 8fa358bde83d79e02f2b65a8d7e8bf47 346 Gene3D G3DSA:3.60.10.10 10 345 8.9E-24 T 12-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily VAPA_1c38070 8fa358bde83d79e02f2b65a8d7e8bf47 346 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 49 334 1.1E-10 T 12-10-2018 IPR005135 Endonuclease/exonuclease/phosphatase VAPA_1c38070 8fa358bde83d79e02f2b65a8d7e8bf47 346 SUPERFAMILY SSF56219 10 342 2.64E-29 T 12-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily VAPA_1c24310 793b5145de9d8d70c140ffecce51cfcc 176 SUPERFAMILY SSF46626 43 157 1.38E-11 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 VAPA_1c24310 793b5145de9d8d70c140ffecce51cfcc 176 Gene3D G3DSA:1.10.760.10 8 153 5.2E-14 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 VAPA_1c46660 8d74fb896867d5cc7ba23903bd82f7c4 202 SUPERFAMILY SSF51206 17 150 6.28E-20 T 12-10-2018 IPR018490 Cyclic nucleotide-binding-like VAPA_1c46660 8d74fb896867d5cc7ba23903bd82f7c4 202 SMART SM00100 22 140 0.0021 T 12-10-2018 IPR000595 Cyclic nucleotide-binding domain VAPA_1c46660 8d74fb896867d5cc7ba23903bd82f7c4 202 Pfam PF00027 Cyclic nucleotide-binding domain 45 129 2.4E-8 T 12-10-2018 IPR000595 Cyclic nucleotide-binding domain VAPA_1c46660 8d74fb896867d5cc7ba23903bd82f7c4 202 Gene3D G3DSA:2.60.120.10 9 149 1.4E-16 T 12-10-2018 IPR014710 RmlC-like jelly roll fold VAPA_1c34700 b74aad35bb96eb7a0679a2eafaf067de 431 Gene3D G3DSA:3.30.70.100 318 411 6.5E-17 T 12-10-2018 VAPA_1c34700 b74aad35bb96eb7a0679a2eafaf067de 431 Pfam PF00924 Mechanosensitive ion channel 207 407 5.2E-45 T 12-10-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 VAPA_1c34700 b74aad35bb96eb7a0679a2eafaf067de 431 SUPERFAMILY SSF82689 322 417 2.75E-22 T 12-10-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 VAPA_1c34700 b74aad35bb96eb7a0679a2eafaf067de 431 SUPERFAMILY SSF82861 170 248 1.96E-10 T 12-10-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 VAPA_1c34700 b74aad35bb96eb7a0679a2eafaf067de 431 Gene3D G3DSA:2.30.30.60 266 314 3.2E-7 T 12-10-2018 IPR023408 Mechanosensitive ion channel MscS domain superfamily VAPA_1c34700 b74aad35bb96eb7a0679a2eafaf067de 431 SUPERFAMILY SSF50182 250 315 8.5E-14 T 12-10-2018 IPR010920 LSM domain superfamily VAPA_1c38410 af82b68d977768f41e3f7a22f912dd12 316 Pfam PF03547 Membrane transport protein 170 308 9.5E-18 T 12-10-2018 IPR004776 Membrane transport protein GO:0016021|GO:0055085 VAPA_1c38410 af82b68d977768f41e3f7a22f912dd12 316 Pfam PF03547 Membrane transport protein 5 150 1.1E-11 T 12-10-2018 IPR004776 Membrane transport protein GO:0016021|GO:0055085 VAPA_1c14560 804e42ffff46593e280d078d99ca0969 422 Pfam PF01594 AI-2E family transporter 71 409 1.0E-53 T 12-10-2018 IPR002549 Transmembrane protein TqsA-like VAPA_1c18430 82d3554a136f8f3164f90306e1185b85 315 SUPERFAMILY SSF51569 6 289 3.96E-64 T 12-10-2018 VAPA_1c18430 82d3554a136f8f3164f90306e1185b85 315 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 17 33 - T 12-10-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 VAPA_1c18430 82d3554a136f8f3164f90306e1185b85 315 Gene3D G3DSA:3.20.20.70 8 292 3.3E-98 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 VAPA_1c18430 82d3554a136f8f3164f90306e1185b85 315 Pfam PF00682 HMGL-like 14 284 1.1E-39 T 12-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 VAPA_1c23770 b52f8081700885c39650a8f800c18dbb 386 PIRSF PIRSF001549 5 334 3.2E-48 T 12-10-2018 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 VAPA_1c23770 b52f8081700885c39650a8f800c18dbb 386 TIGRFAM TIGR00443 hisZ_biosyn_reg: ATP phosphoribosyltransferase, regulatory subunit 12 321 3.8E-83 T 12-10-2018 IPR004517 ATP phosphoribosyltransferase regulatory subunit GO:0000105|GO:0005737 VAPA_1c23770 b52f8081700885c39650a8f800c18dbb 386 Pfam PF13393 Histidyl-tRNA synthetase 10 317 6.9E-113 T 12-10-2018 VAPA_1c23770 b52f8081700885c39650a8f800c18dbb 386 Gene3D G3DSA:3.30.930.10 3 327 9.7E-71 T 12-10-2018 VAPA_1c23770 b52f8081700885c39650a8f800c18dbb 386 Hamap MF_00125 ATP phosphoribosyltransferase regulatory subunit [hisZ]. 16 368 32.252 T 12-10-2018 IPR004517 ATP phosphoribosyltransferase regulatory subunit GO:0000105|GO:0005737 VAPA_1c23770 b52f8081700885c39650a8f800c18dbb 386 SUPERFAMILY SSF55681 6 320 2.19E-57 T 12-10-2018 VAPA_2c04530 b91ff48cf5cfe9609f95e0cdc744dc5f 510 TIGRFAM TIGR01660 narH: nitrate reductase, beta subunit 1 495 5.9E-291 T 12-10-2018 IPR006547 Nitrate reductase, beta subunit GO:0008940|GO:0009325|GO:0042126|GO:0055114 KEGG: 00910+1.7.5.1|MetaCyc: PWY-6748 VAPA_2c04530 b91ff48cf5cfe9609f95e0cdc744dc5f 510 Gene3D G3DSA:1.10.3650.10 361 437 3.2E-29 T 12-10-2018 IPR038262 Nitrate reductase beta, C-terminal domain superfamily KEGG: 00910+1.7.5.1|MetaCyc: PWY-6748 VAPA_2c04530 b91ff48cf5cfe9609f95e0cdc744dc5f 510 SUPERFAMILY SSF54862 1 507 1.36E-180 T 12-10-2018 VAPA_2c04530 b91ff48cf5cfe9609f95e0cdc744dc5f 510 Gene3D G3DSA:3.30.70.20 1 301 1.9E-102 T 12-10-2018 VAPA_2c04530 b91ff48cf5cfe9609f95e0cdc744dc5f 510 Pfam PF13247 4Fe-4S dicluster domain 178 274 1.9E-37 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain VAPA_2c04530 b91ff48cf5cfe9609f95e0cdc744dc5f 510 Pfam PF14711 Respiratory nitrate reductase beta C-terminal 361 438 9.0E-28 T 12-10-2018 IPR029263 Respiratory nitrate reductase beta, C-terminal KEGG: 00910+1.7.5.1|MetaCyc: PWY-6748 VAPA_1c23860 c32a22e35d4ed56492c0c9b9f549c965 240 ProSitePatterns PS00211 ABC transporters family signature. 148 162 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_1c23860 c32a22e35d4ed56492c0c9b9f549c965 240 SUPERFAMILY SSF52540 10 227 3.1E-65 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c23860 c32a22e35d4ed56492c0c9b9f549c965 240 Gene3D G3DSA:3.40.50.300 7 238 4.6E-66 T 12-10-2018 VAPA_1c23860 c32a22e35d4ed56492c0c9b9f549c965 240 SMART SM00382 38 226 1.1E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c23860 c32a22e35d4ed56492c0c9b9f549c965 240 Pfam PF00005 ABC transporter 29 175 4.7E-32 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c48160 8a079ce35281f315c8eade2cc985594c 330 Gene3D G3DSA:3.40.190.150 34 320 1.4E-113 T 12-10-2018 VAPA_1c48160 8a079ce35281f315c8eade2cc985594c 330 SUPERFAMILY SSF53850 120 291 3.02E-17 T 12-10-2018 VAPA_1c48160 8a079ce35281f315c8eade2cc985594c 330 Gene3D G3DSA:3.40.190.10 132 254 1.4E-113 T 12-10-2018 VAPA_1c48160 8a079ce35281f315c8eade2cc985594c 330 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 53 327 1.9E-86 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c48160 8a079ce35281f315c8eade2cc985594c 330 PIRSF PIRSF017082 1 329 1.8E-85 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c43260 dbde78c3be804db3e703068c6ab440da 331 Pfam PF14842 FliG N-terminal domain 5 100 9.0E-28 T 12-10-2018 IPR028263 Flagellar motor switch protein FliG, N-terminal domain VAPA_1c43260 dbde78c3be804db3e703068c6ab440da 331 PRINTS PR00954 Flagellar motor switch protein FliG signature 113 136 1.9E-64 T 12-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 VAPA_1c43260 dbde78c3be804db3e703068c6ab440da 331 PRINTS PR00954 Flagellar motor switch protein FliG signature 3 19 1.9E-64 T 12-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 VAPA_1c43260 dbde78c3be804db3e703068c6ab440da 331 PRINTS PR00954 Flagellar motor switch protein FliG signature 193 218 1.9E-64 T 12-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 VAPA_1c43260 dbde78c3be804db3e703068c6ab440da 331 PRINTS PR00954 Flagellar motor switch protein FliG signature 270 296 1.9E-64 T 12-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 VAPA_1c43260 dbde78c3be804db3e703068c6ab440da 331 PRINTS PR00954 Flagellar motor switch protein FliG signature 224 244 1.9E-64 T 12-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 VAPA_1c43260 dbde78c3be804db3e703068c6ab440da 331 PRINTS PR00954 Flagellar motor switch protein FliG signature 246 266 1.9E-64 T 12-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 VAPA_1c43260 dbde78c3be804db3e703068c6ab440da 331 PRINTS PR00954 Flagellar motor switch protein FliG signature 32 58 1.9E-64 T 12-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 VAPA_1c43260 dbde78c3be804db3e703068c6ab440da 331 TIGRFAM TIGR00207 fliG: flagellar motor switch protein FliG 5 330 3.4E-111 T 12-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 VAPA_1c43260 dbde78c3be804db3e703068c6ab440da 331 Pfam PF01706 FliG C-terminal domain 217 321 3.2E-38 T 12-10-2018 IPR023087 Flagellar motor switch protein FliG, C-terminal VAPA_1c43260 dbde78c3be804db3e703068c6ab440da 331 Pfam PF14841 FliG middle domain 116 185 1.5E-22 T 12-10-2018 IPR032779 Flagellar motor switch protein FliG, middle domain VAPA_1c43260 dbde78c3be804db3e703068c6ab440da 331 Gene3D G3DSA:1.10.220.30 88 191 1.8E-23 T 12-10-2018 VAPA_1c43260 dbde78c3be804db3e703068c6ab440da 331 PIRSF PIRSF003161 1 331 3.0E-104 T 12-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 VAPA_1c43260 dbde78c3be804db3e703068c6ab440da 331 Gene3D G3DSA:1.10.220.30 3 84 5.8E-17 T 12-10-2018 VAPA_1c43260 dbde78c3be804db3e703068c6ab440da 331 SUPERFAMILY SSF48029 3 103 2.88E-19 T 12-10-2018 IPR011002 Flagellar motor switch protein FliG, alpha-helical VAPA_1c43260 dbde78c3be804db3e703068c6ab440da 331 SUPERFAMILY SSF48029 116 322 1.18E-59 T 12-10-2018 IPR011002 Flagellar motor switch protein FliG, alpha-helical VAPA_1c43260 dbde78c3be804db3e703068c6ab440da 331 Gene3D G3DSA:1.10.220.30 193 331 7.1E-41 T 12-10-2018 VAPA_2c05120 2f47dd841efbc75d29620cd58275010c 743 Pfam PF13844 Glycosyl transferase family 41 532 726 2.9E-51 T 12-10-2018 IPR029489 O-GlcNAc transferase, C-terminal KEGG: 00514+2.4.1.255|MetaCyc: PWY-7437|Reactome: R-HSA-3214847|Reactome: R-HSA-5689603 VAPA_2c05120 2f47dd841efbc75d29620cd58275010c 743 Pfam PF13844 Glycosyl transferase family 41 367 513 3.3E-35 T 12-10-2018 IPR029489 O-GlcNAc transferase, C-terminal KEGG: 00514+2.4.1.255|MetaCyc: PWY-7437|Reactome: R-HSA-3214847|Reactome: R-HSA-5689603 VAPA_2c05120 2f47dd841efbc75d29620cd58275010c 743 Gene3D G3DSA:3.40.50.11380 353 714 4.6E-141 T 12-10-2018 VAPA_2c05120 2f47dd841efbc75d29620cd58275010c 743 SUPERFAMILY SSF48452 16 239 6.45E-30 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 VAPA_2c05120 2f47dd841efbc75d29620cd58275010c 743 Gene3D G3DSA:3.40.50.2000 530 708 4.6E-141 T 12-10-2018 VAPA_2c05120 2f47dd841efbc75d29620cd58275010c 743 SMART SM00028 76 109 5.9E-5 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 VAPA_2c05120 2f47dd841efbc75d29620cd58275010c 743 SMART SM00028 144 177 0.28 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 VAPA_2c05120 2f47dd841efbc75d29620cd58275010c 743 SMART SM00028 110 143 0.0058 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 VAPA_2c05120 2f47dd841efbc75d29620cd58275010c 743 SMART SM00028 212 245 28.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 VAPA_2c05120 2f47dd841efbc75d29620cd58275010c 743 SMART SM00028 252 285 100.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 VAPA_2c05120 2f47dd841efbc75d29620cd58275010c 743 Pfam PF13432 Tetratricopeptide repeat 13 61 0.0036 T 12-10-2018 VAPA_2c05120 2f47dd841efbc75d29620cd58275010c 743 Pfam PF13432 Tetratricopeptide repeat 82 144 8.7E-9 T 12-10-2018 VAPA_2c05120 2f47dd841efbc75d29620cd58275010c 743 Gene3D G3DSA:1.25.40.10 2 285 1.8E-44 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 VAPA_1c09900 1d53da21e6a1d457ae3ded9cc3e744fe 197 SUPERFAMILY SSF53474 8 195 1.08E-18 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c09900 1d53da21e6a1d457ae3ded9cc3e744fe 197 Gene3D G3DSA:3.40.50.1820 5 196 1.2E-54 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c09900 1d53da21e6a1d457ae3ded9cc3e744fe 197 Pfam PF05728 Uncharacterised protein family (UPF0227) 8 194 1.5E-48 T 12-10-2018 IPR008886 Uncharacterised protein family UPF0227/Esterase YqiA VAPA_2c01640 ce70de3b642245b7368f3ee17e86618e 140 Gene3D G3DSA:3.10.180.10 2 139 1.6E-50 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase VAPA_2c01640 ce70de3b642245b7368f3ee17e86618e 140 SUPERFAMILY SSF54593 4 136 4.56E-29 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase VAPA_2c01640 ce70de3b642245b7368f3ee17e86618e 140 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 5 129 8.4E-12 T 12-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain VAPA_2c01050 034083f3d87fe2d84671ea08abbaecfa 267 Pfam PF00378 Enoyl-CoA hydratase/isomerase 12 258 1.4E-52 T 12-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 VAPA_2c01050 034083f3d87fe2d84671ea08abbaecfa 267 Gene3D G3DSA:1.10.12.10 205 263 2.1E-9 T 12-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal VAPA_2c01050 034083f3d87fe2d84671ea08abbaecfa 267 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 103 123 - T 12-10-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824 VAPA_2c01050 034083f3d87fe2d84671ea08abbaecfa 267 SUPERFAMILY SSF52096 3 258 9.08E-73 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily VAPA_2c01050 034083f3d87fe2d84671ea08abbaecfa 267 Gene3D G3DSA:3.90.226.10 2 203 1.8E-65 T 12-10-2018 VAPA_1c13540 54f85cebbc675f5517033bd9bdebbf34 430 Pfam PF12002 MgsA AAA+ ATPase C terminal 255 421 1.5E-68 T 12-10-2018 IPR021886 MgsA AAA+ ATPase C-terminal VAPA_1c13540 54f85cebbc675f5517033bd9bdebbf34 430 Pfam PF16193 AAA C-terminal domain 181 254 4.5E-23 T 12-10-2018 IPR032423 AAA C-terminal domain VAPA_1c13540 54f85cebbc675f5517033bd9bdebbf34 430 Gene3D G3DSA:1.10.3710.10 333 430 1.8E-36 T 12-10-2018 VAPA_1c13540 54f85cebbc675f5517033bd9bdebbf34 430 Gene3D G3DSA:1.20.272.10 228 332 5.9E-46 T 12-10-2018 VAPA_1c13540 54f85cebbc675f5517033bd9bdebbf34 430 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 47 155 1.2E-13 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 VAPA_1c13540 54f85cebbc675f5517033bd9bdebbf34 430 Gene3D G3DSA:3.40.50.300 1 158 4.3E-41 T 12-10-2018 VAPA_1c13540 54f85cebbc675f5517033bd9bdebbf34 430 SMART SM00382 42 160 1.5E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c13540 54f85cebbc675f5517033bd9bdebbf34 430 SUPERFAMILY SSF52540 4 223 3.29E-44 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c13540 54f85cebbc675f5517033bd9bdebbf34 430 SUPERFAMILY SSF48019 239 421 1.02E-75 T 12-10-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 VAPA_1c13540 54f85cebbc675f5517033bd9bdebbf34 430 Gene3D G3DSA:1.10.8.60 160 227 4.5E-7 T 12-10-2018 VAPA_1c54720 27a876ccde4cbbf2cbdf102b104cf7b2 464 Gene3D G3DSA:3.90.230.10 171 464 4.4E-85 T 12-10-2018 VAPA_1c54720 27a876ccde4cbbf2cbdf102b104cf7b2 464 SMART SM01011 4 135 8.2E-62 T 12-10-2018 IPR007865 Aminopeptidase P, N-terminal GO:0004177|GO:0030145 VAPA_1c54720 27a876ccde4cbbf2cbdf102b104cf7b2 464 SUPERFAMILY SSF53092 7 173 2.75E-50 T 12-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal VAPA_1c54720 27a876ccde4cbbf2cbdf102b104cf7b2 464 ProSitePatterns PS00491 Aminopeptidase P and proline dipeptidase signature. 357 369 - T 12-10-2018 IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site VAPA_1c54720 27a876ccde4cbbf2cbdf102b104cf7b2 464 Gene3D G3DSA:3.40.350.10 5 170 1.7E-47 T 12-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal VAPA_1c54720 27a876ccde4cbbf2cbdf102b104cf7b2 464 SUPERFAMILY SSF55920 174 462 8.24E-75 T 12-10-2018 IPR036005 Creatinase/aminopeptidase-like VAPA_1c54720 27a876ccde4cbbf2cbdf102b104cf7b2 464 Pfam PF05195 Aminopeptidase P, N-terminal domain 9 125 4.8E-35 T 12-10-2018 IPR007865 Aminopeptidase P, N-terminal GO:0004177|GO:0030145 VAPA_1c54720 27a876ccde4cbbf2cbdf102b104cf7b2 464 Pfam PF00557 Metallopeptidase family M24 180 441 5.4E-56 T 12-10-2018 IPR000994 Peptidase M24 VAPA_1c04640 c27159161b5ec1287d01fb9d457d0ca7 369 Pfam PF03054 tRNA methyl transferase 4 368 1.8E-129 T 12-10-2018 VAPA_1c04640 c27159161b5ec1287d01fb9d457d0ca7 369 Gene3D G3DSA:2.30.30.280 212 286 4.0E-27 T 12-10-2018 IPR023382 Adenine nucleotide alpha hydrolase-like domains GO:0016783 MetaCyc: PWY-7887|MetaCyc: PWY-7892|Reactome: R-HSA-6787450 VAPA_1c04640 c27159161b5ec1287d01fb9d457d0ca7 369 Gene3D G3DSA:2.40.30.10 288 369 3.1E-21 T 12-10-2018 VAPA_1c04640 c27159161b5ec1287d01fb9d457d0ca7 369 Hamap MF_00144 tRNA-specific 2-thiouridylase MnmA [mnmA]. 4 369 38.865 T 12-10-2018 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 MetaCyc: PWY-7887|MetaCyc: PWY-7892|Reactome: R-HSA-6787450 VAPA_1c04640 c27159161b5ec1287d01fb9d457d0ca7 369 SUPERFAMILY SSF52402 3 243 2.21E-56 T 12-10-2018 VAPA_1c04640 c27159161b5ec1287d01fb9d457d0ca7 369 Gene3D G3DSA:3.40.50.620 1 211 7.7E-90 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold VAPA_1c04640 c27159161b5ec1287d01fb9d457d0ca7 369 TIGRFAM TIGR00420 trmU: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase 5 368 1.1E-126 T 12-10-2018 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 MetaCyc: PWY-7887|MetaCyc: PWY-7892|Reactome: R-HSA-6787450 VAPA_1c07290 0d148ae8f06b181a0f4bfd6e72c7fa2d 266 SUPERFAMILY SSF51366 12 265 2.94E-85 T 12-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 VAPA_1c07290 0d148ae8f06b181a0f4bfd6e72c7fa2d 266 ProSitePatterns PS00614 Indole-3-glycerol phosphate synthase signature. 56 74 - T 12-10-2018 IPR001468 Indole-3-glycerol phosphate synthase, conserved site GO:0004425|GO:0006568 KEGG: 00400+4.1.1.48 VAPA_1c07290 0d148ae8f06b181a0f4bfd6e72c7fa2d 266 Gene3D G3DSA:3.20.20.70 1 266 2.9E-102 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 VAPA_1c07290 0d148ae8f06b181a0f4bfd6e72c7fa2d 266 Hamap MF_00134_B Indole-3-glycerol phosphate synthase [trpC]. 3 266 35.588 T 12-10-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 VAPA_1c07290 0d148ae8f06b181a0f4bfd6e72c7fa2d 266 Pfam PF00218 Indole-3-glycerol phosphate synthase 5 263 1.2E-91 T 12-10-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 VAPA_1c51560 b7e02904bfddd986b18d34cae1afc4e7 151 SMART SM00347 35 134 1.1E-23 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 VAPA_1c51560 b7e02904bfddd986b18d34cae1afc4e7 151 Gene3D G3DSA:1.10.10.10 6 150 2.0E-37 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c51560 b7e02904bfddd986b18d34cae1afc4e7 151 SUPERFAMILY SSF46785 8 148 2.57E-35 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c51560 b7e02904bfddd986b18d34cae1afc4e7 151 PRINTS PR00598 Bacterial regulatory protein MarR family signature 95 111 4.1E-7 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 VAPA_1c51560 b7e02904bfddd986b18d34cae1afc4e7 151 PRINTS PR00598 Bacterial regulatory protein MarR family signature 76 91 4.1E-7 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 VAPA_1c51560 b7e02904bfddd986b18d34cae1afc4e7 151 PRINTS PR00598 Bacterial regulatory protein MarR family signature 59 75 4.1E-7 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 VAPA_1c51560 b7e02904bfddd986b18d34cae1afc4e7 151 Pfam PF01047 MarR family 42 100 2.2E-16 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 VAPA_2c12490 c2a4e45bff211366b9c60d90733bdfeb 159 Gene3D G3DSA:3.40.630.30 1 151 1.2E-38 T 12-10-2018 VAPA_2c12490 c2a4e45bff211366b9c60d90733bdfeb 159 Pfam PF00583 Acetyltransferase (GNAT) family 50 138 1.9E-13 T 12-10-2018 IPR000182 GNAT domain VAPA_2c12490 c2a4e45bff211366b9c60d90733bdfeb 159 SUPERFAMILY SSF55729 1 144 2.16E-20 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase VAPA_2c11700 6c0da2862af3b93a60e0a12622894c96 481 Pfam PF05598 Transposase domain (DUF772) 56 123 1.9E-17 T 12-10-2018 IPR008490 Transposase InsH, N-terminal VAPA_2c11700 6c0da2862af3b93a60e0a12622894c96 481 Pfam PF13751 Transposase DDE domain 348 463 1.0E-16 T 12-10-2018 IPR025668 Transposase DDE domain VAPA_1c48350 e92e4e40db3fca29ec64826f6b6d106c 479 SMART SM00996 14 478 0.0 T 12-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 VAPA_1c48350 e92e4e40db3fca29ec64826f6b6d106c 479 Gene3D G3DSA:3.40.50.1480 17 479 4.5E-233 T 12-10-2018 VAPA_1c48350 e92e4e40db3fca29ec64826f6b6d106c 479 Pfam PF05221 S-adenosyl-L-homocysteine hydrolase 16 478 4.0E-139 T 12-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 VAPA_1c48350 e92e4e40db3fca29ec64826f6b6d106c 479 ProSitePatterns PS00738 S-adenosyl-L-homocysteine hydrolase signature 1. 86 100 - T 12-10-2018 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 VAPA_1c48350 e92e4e40db3fca29ec64826f6b6d106c 479 SUPERFAMILY SSF52283 13 479 1.13E-107 T 12-10-2018 VAPA_1c48350 e92e4e40db3fca29ec64826f6b6d106c 479 Pfam PF00670 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 239 398 2.3E-82 T 12-10-2018 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 VAPA_1c48350 e92e4e40db3fca29ec64826f6b6d106c 479 PIRSF PIRSF001109 1 479 1.7E-186 T 12-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 VAPA_1c48350 e92e4e40db3fca29ec64826f6b6d106c 479 Hamap MF_00563 Adenosylhomocysteinase [ahcY]. 10 471 47.688 T 12-10-2018 IPR034373 Adenosylhomocysteinase GO:0004013|GO:0019510|GO:0051287 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-2408508|Reactome: R-HSA-5578997 VAPA_1c48350 e92e4e40db3fca29ec64826f6b6d106c 479 Gene3D G3DSA:3.40.50.720 241 398 4.5E-233 T 12-10-2018 VAPA_1c48350 e92e4e40db3fca29ec64826f6b6d106c 479 TIGRFAM TIGR00936 ahcY: adenosylhomocysteinase 17 471 7.7E-182 T 12-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 VAPA_1c48350 e92e4e40db3fca29ec64826f6b6d106c 479 ProSitePatterns PS00739 S-adenosyl-L-homocysteine hydrolase signature 2. 261 277 - T 12-10-2018 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 VAPA_1c48350 e92e4e40db3fca29ec64826f6b6d106c 479 SUPERFAMILY SSF51735 239 398 9.22E-79 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c48350 e92e4e40db3fca29ec64826f6b6d106c 479 SMART SM00997 239 398 1.6E-115 T 12-10-2018 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 VAPA_1c41790 16d4277e587aa0a81202ebce28e20994 322 Gene3D G3DSA:3.40.50.11270 17 101 9.1E-114 T 12-10-2018 VAPA_1c41790 16d4277e587aa0a81202ebce28e20994 322 Hamap MF_00191 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [ispH]. 6 288 38.142 T 12-10-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 VAPA_1c41790 16d4277e587aa0a81202ebce28e20994 322 Gene3D G3DSA:3.40.1010.20 11 282 9.1E-114 T 12-10-2018 VAPA_1c41790 16d4277e587aa0a81202ebce28e20994 322 Pfam PF02401 LytB protein 8 284 1.0E-94 T 12-10-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 VAPA_1c41790 16d4277e587aa0a81202ebce28e20994 322 Gene3D G3DSA:3.40.1010.20 102 198 9.1E-114 T 12-10-2018 VAPA_1c41790 16d4277e587aa0a81202ebce28e20994 322 TIGRFAM TIGR00216 ispH_lytB: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 7 286 1.1E-101 T 12-10-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 VAPA_1c27410 6d89dc7eee6f4ff1f030f96a60b464e8 240 Gene3D G3DSA:3.40.50.300 4 225 2.7E-66 T 12-10-2018 VAPA_1c27410 6d89dc7eee6f4ff1f030f96a60b464e8 240 TIGRFAM TIGR00347 bioD: dethiobiotin synthase 7 176 9.0E-46 T 12-10-2018 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 VAPA_1c27410 6d89dc7eee6f4ff1f030f96a60b464e8 240 PIRSF PIRSF006755 2 233 4.6E-65 T 12-10-2018 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 VAPA_1c27410 6d89dc7eee6f4ff1f030f96a60b464e8 240 Pfam PF13500 AAA domain 5 210 7.2E-38 T 12-10-2018 VAPA_1c27410 6d89dc7eee6f4ff1f030f96a60b464e8 240 Hamap MF_00336 ATP-dependent dethiobiotin synthetase BioD [bioD]. 3 218 29.258 T 12-10-2018 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 VAPA_1c27410 6d89dc7eee6f4ff1f030f96a60b464e8 240 SUPERFAMILY SSF52540 1 215 3.9E-59 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c02850 1454b103904b80257e6907da7dd3a2e7 296 SUPERFAMILY SSF103481 39 132 9.55E-12 T 12-10-2018 VAPA_1c02850 1454b103904b80257e6907da7dd3a2e7 296 SUPERFAMILY SSF103481 189 282 1.7E-5 T 12-10-2018 VAPA_1c02850 1454b103904b80257e6907da7dd3a2e7 296 Pfam PF00892 EamA-like transporter family 3 130 8.4E-13 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 VAPA_1c03460 64b45185d6766c543b52aa511bbb745f 347 TIGRFAM TIGR00904 mreB: cell shape determining protein, MreB/Mrl family 9 340 5.3E-153 T 12-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 VAPA_1c03460 64b45185d6766c543b52aa511bbb745f 347 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 137 156 5.0E-62 T 12-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 VAPA_1c03460 64b45185d6766c543b52aa511bbb745f 347 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 305 331 5.0E-62 T 12-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 VAPA_1c03460 64b45185d6766c543b52aa511bbb745f 347 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 73 96 5.0E-62 T 12-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 VAPA_1c03460 64b45185d6766c543b52aa511bbb745f 347 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 192 212 5.0E-62 T 12-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 VAPA_1c03460 64b45185d6766c543b52aa511bbb745f 347 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 53 71 5.0E-62 T 12-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 VAPA_1c03460 64b45185d6766c543b52aa511bbb745f 347 Gene3D G3DSA:3.90.640.10 191 264 8.3E-130 T 12-10-2018 VAPA_1c03460 64b45185d6766c543b52aa511bbb745f 347 Pfam PF06723 MreB/Mbl protein 11 340 2.7E-146 T 12-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 VAPA_1c03460 64b45185d6766c543b52aa511bbb745f 347 Gene3D G3DSA:3.30.420.40 159 322 8.3E-130 T 12-10-2018 VAPA_1c03460 64b45185d6766c543b52aa511bbb745f 347 SUPERFAMILY SSF53067 154 339 4.33E-49 T 12-10-2018 VAPA_1c03460 64b45185d6766c543b52aa511bbb745f 347 Gene3D G3DSA:3.30.420.40 13 332 8.3E-130 T 12-10-2018 VAPA_1c03460 64b45185d6766c543b52aa511bbb745f 347 SUPERFAMILY SSF53067 9 153 1.3E-37 T 12-10-2018 VAPA_1c27890 866036da2fdb9385a48d4bddb97c12fc 199 Gene3D G3DSA:3.40.50.720 1 188 6.0E-47 T 12-10-2018 VAPA_1c27890 866036da2fdb9385a48d4bddb97c12fc 199 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 3 91 2.6E-22 T 12-10-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal VAPA_1c27890 866036da2fdb9385a48d4bddb97c12fc 199 SUPERFAMILY SSF51735 1 180 3.67E-29 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c31160 f7a608d5c4af0e95e429e7507e39d7fd 334 SMART SM00327 81 262 3.4E-11 T 12-10-2018 IPR002035 von Willebrand factor, type A VAPA_1c31160 f7a608d5c4af0e95e429e7507e39d7fd 334 Gene3D G3DSA:3.40.50.410 82 288 1.8E-23 T 12-10-2018 IPR036465 von Willebrand factor A-like domain superfamily VAPA_1c31160 f7a608d5c4af0e95e429e7507e39d7fd 334 SUPERFAMILY SSF53300 81 240 1.48E-17 T 12-10-2018 IPR036465 von Willebrand factor A-like domain superfamily VAPA_1c31160 f7a608d5c4af0e95e429e7507e39d7fd 334 Pfam PF13519 von Willebrand factor type A domain 84 202 1.8E-12 T 12-10-2018 IPR002035 von Willebrand factor, type A VAPA_1c07660 ac203bb413db382f764430b42d92c43a 304 Gene3D G3DSA:1.10.10.10 6 93 8.9E-22 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c07660 ac203bb413db382f764430b42d92c43a 304 Gene3D G3DSA:3.40.190.290 95 304 2.9E-37 T 12-10-2018 VAPA_1c07660 ac203bb413db382f764430b42d92c43a 304 Pfam PF03466 LysR substrate binding domain 93 299 1.3E-37 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_1c07660 ac203bb413db382f764430b42d92c43a 304 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 11 67 3.3E-18 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c07660 ac203bb413db382f764430b42d92c43a 304 SUPERFAMILY SSF46785 9 116 2.51E-20 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c07660 ac203bb413db382f764430b42d92c43a 304 SUPERFAMILY SSF53850 95 301 1.52E-37 T 12-10-2018 VAPA_1c06560 3d9ad5383fe9f0bfb3cd6f33eb50bf45 289 SUPERFAMILY SSF56300 2 196 2.69E-22 T 12-10-2018 VAPA_1c06560 3d9ad5383fe9f0bfb3cd6f33eb50bf45 289 Pfam PF09722 Protein of unknown function (DUF2384) 240 286 3.9E-7 T 12-10-2018 IPR024467 Domain of unknown function DUF2384 VAPA_1c06560 3d9ad5383fe9f0bfb3cd6f33eb50bf45 289 Pfam PF00149 Calcineurin-like phosphoesterase 2 193 2.6E-14 T 12-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 VAPA_2c02520 fd27da9d188bb084383299e2b03581ae 371 Gene3D G3DSA:2.40.37.20 16 367 2.4E-133 T 12-10-2018 VAPA_2c02520 fd27da9d188bb084383299e2b03581ae 371 SUPERFAMILY SSF51419 23 257 4.97E-45 T 12-10-2018 IPR029066 PLP-binding barrel VAPA_2c02520 fd27da9d188bb084383299e2b03581ae 371 Pfam PF01168 Alanine racemase, N-terminal domain 23 250 3.5E-29 T 12-10-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 VAPA_2c02520 fd27da9d188bb084383299e2b03581ae 371 SMART SM01119 267 354 5.4E-36 T 12-10-2018 IPR026956 D-serine dehydratase-like domain VAPA_2c02520 fd27da9d188bb084383299e2b03581ae 371 Gene3D G3DSA:3.20.20.10 25 247 2.4E-133 T 12-10-2018 IPR029066 PLP-binding barrel VAPA_2c02520 fd27da9d188bb084383299e2b03581ae 371 Pfam PF14031 Putative serine dehydratase domain 267 353 8.9E-23 T 12-10-2018 IPR026956 D-serine dehydratase-like domain VAPA_1c38970 c5575f8e8c8be04fa8e3ac7bd931b297 278 PIRSF PIRSF032817 44 278 2.7E-60 T 12-10-2018 IPR017008 Uncharacterised conserved protein UCP032817 VAPA_1c17030 da226e28ea8c97b90b69b63e2b4dd39b 169 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 24 153 6.9E-24 T 12-10-2018 IPR007387 TRAP transporter, small membrane protein DctQ VAPA_1c03150 5c3b31e3facdcb01f143bb0ba48a493d 309 Gene3D G3DSA:3.30.565.10 162 308 2.7E-35 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_1c03150 5c3b31e3facdcb01f143bb0ba48a493d 309 PRINTS PR00344 Bacterial sensor protein C-terminal signature 233 247 2.7E-18 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c03150 5c3b31e3facdcb01f143bb0ba48a493d 309 PRINTS PR00344 Bacterial sensor protein C-terminal signature 267 285 2.7E-18 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c03150 5c3b31e3facdcb01f143bb0ba48a493d 309 PRINTS PR00344 Bacterial sensor protein C-terminal signature 291 304 2.7E-18 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c03150 5c3b31e3facdcb01f143bb0ba48a493d 309 PRINTS PR00344 Bacterial sensor protein C-terminal signature 251 261 2.7E-18 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c03150 5c3b31e3facdcb01f143bb0ba48a493d 309 Gene3D G3DSA:1.10.287.130 39 149 6.9E-27 T 12-10-2018 VAPA_1c03150 5c3b31e3facdcb01f143bb0ba48a493d 309 SUPERFAMILY SSF47384 79 156 2.35E-14 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 VAPA_1c03150 5c3b31e3facdcb01f143bb0ba48a493d 309 SMART SM00304 42 94 1.8E-10 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 VAPA_1c03150 5c3b31e3facdcb01f143bb0ba48a493d 309 Pfam PF00672 HAMP domain 42 90 4.5E-8 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 VAPA_1c03150 5c3b31e3facdcb01f143bb0ba48a493d 309 SUPERFAMILY SSF55874 146 305 2.88E-34 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_1c03150 5c3b31e3facdcb01f143bb0ba48a493d 309 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 199 305 6.6E-22 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase VAPA_1c03150 5c3b31e3facdcb01f143bb0ba48a493d 309 SMART SM00388 95 156 2.8E-10 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 VAPA_1c03150 5c3b31e3facdcb01f143bb0ba48a493d 309 Pfam PF00512 His Kinase A (phospho-acceptor) domain 97 155 4.5E-10 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 VAPA_1c03150 5c3b31e3facdcb01f143bb0ba48a493d 309 SUPERFAMILY SSF158472 42 92 3.66E-6 T 12-10-2018 VAPA_1c03150 5c3b31e3facdcb01f143bb0ba48a493d 309 SMART SM00387 198 307 1.5E-31 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase VAPA_1c29010 430bd7ec40c10c5b256428a1eb5dfa88 773 SMART SM00382 495 644 3.4E-9 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c29010 430bd7ec40c10c5b256428a1eb5dfa88 773 SMART SM00382 214 358 3.6E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c29010 430bd7ec40c10c5b256428a1eb5dfa88 773 SMART SM01086 661 750 2.1E-29 T 12-10-2018 IPR019489 Clp ATPase, C-terminal VAPA_1c29010 430bd7ec40c10c5b256428a1eb5dfa88 773 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 310 322 - T 12-10-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 VAPA_1c29010 430bd7ec40c10c5b256428a1eb5dfa88 773 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 526 544 - T 12-10-2018 IPR028299 ClpA/B, conserved site 2 VAPA_1c29010 430bd7ec40c10c5b256428a1eb5dfa88 773 SUPERFAMILY SSF52540 445 746 1.23E-76 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c29010 430bd7ec40c10c5b256428a1eb5dfa88 773 Gene3D G3DSA:3.40.50.300 166 358 1.1E-66 T 12-10-2018 VAPA_1c29010 430bd7ec40c10c5b256428a1eb5dfa88 773 SUPERFAMILY SSF52540 176 424 4.36E-68 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c29010 430bd7ec40c10c5b256428a1eb5dfa88 773 Gene3D G3DSA:1.10.8.60 661 765 1.0E-25 T 12-10-2018 VAPA_1c29010 430bd7ec40c10c5b256428a1eb5dfa88 773 Gene3D G3DSA:1.10.8.60 359 446 2.4E-32 T 12-10-2018 VAPA_1c29010 430bd7ec40c10c5b256428a1eb5dfa88 773 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 13 62 1.0E-14 T 12-10-2018 IPR004176 Clp, N-terminal VAPA_1c29010 430bd7ec40c10c5b256428a1eb5dfa88 773 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 499 517 3.8E-38 T 12-10-2018 IPR001270 ClpA/B family GO:0005524 VAPA_1c29010 430bd7ec40c10c5b256428a1eb5dfa88 773 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 541 559 3.8E-38 T 12-10-2018 IPR001270 ClpA/B family GO:0005524 VAPA_1c29010 430bd7ec40c10c5b256428a1eb5dfa88 773 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 570 588 3.8E-38 T 12-10-2018 IPR001270 ClpA/B family GO:0005524 VAPA_1c29010 430bd7ec40c10c5b256428a1eb5dfa88 773 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 603 617 3.8E-38 T 12-10-2018 IPR001270 ClpA/B family GO:0005524 VAPA_1c29010 430bd7ec40c10c5b256428a1eb5dfa88 773 Gene3D G3DSA:1.10.1780.10 1 144 1.1E-40 T 12-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 VAPA_1c29010 430bd7ec40c10c5b256428a1eb5dfa88 773 Pfam PF07724 AAA domain (Cdc48 subfamily) 494 655 2.0E-46 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 VAPA_1c29010 430bd7ec40c10c5b256428a1eb5dfa88 773 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 219 332 5.1E-12 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 VAPA_1c29010 430bd7ec40c10c5b256428a1eb5dfa88 773 SUPERFAMILY SSF81923 1 143 3.66E-57 T 12-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 VAPA_1c29010 430bd7ec40c10c5b256428a1eb5dfa88 773 TIGRFAM TIGR02639 ClpA: ATP-dependent Clp protease ATP-binding subunit ClpA 3 742 0.0 T 12-10-2018 IPR013461 ATP-dependent Clp protease ATP-binding subunit ClpA GO:0016887|GO:0043335 VAPA_1c29010 430bd7ec40c10c5b256428a1eb5dfa88 773 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 661 740 1.6E-20 T 12-10-2018 IPR019489 Clp ATPase, C-terminal VAPA_1c29010 430bd7ec40c10c5b256428a1eb5dfa88 773 Gene3D G3DSA:3.40.50.300 448 659 7.4E-78 T 12-10-2018 VAPA_1c28160 d8b8e85c982631a409ada9737e59d916 344 SUPERFAMILY SSF161098 112 325 3.01E-19 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c28160 d8b8e85c982631a409ada9737e59d916 344 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 135 342 2.3E-35 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 VAPA_1c28160 d8b8e85c982631a409ada9737e59d916 344 Gene3D G3DSA:1.10.3720.10 107 334 2.4E-23 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c52030 1d7c564cbb0a75e15808f5cff0338645 189 TIGRFAM TIGR01382 PfpI: intracellular protease, PfpI family 12 179 3.4E-48 T 12-10-2018 IPR006286 Deglycase PfpI VAPA_1c52030 1d7c564cbb0a75e15808f5cff0338645 189 Gene3D G3DSA:3.40.50.880 4 184 5.9E-53 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like VAPA_1c52030 1d7c564cbb0a75e15808f5cff0338645 189 Pfam PF01965 DJ-1/PfpI family 11 177 8.0E-53 T 12-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 VAPA_1c52030 1d7c564cbb0a75e15808f5cff0338645 189 SUPERFAMILY SSF52317 10 180 2.64E-49 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like VAPA_1c01130 fd160305e9ec2b6efc7b8b97a83e2222 671 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 27 80 5.1E-12 T 12-10-2018 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857 VAPA_1c01130 fd160305e9ec2b6efc7b8b97a83e2222 671 Gene3D G3DSA:3.40.50.12780 59 528 1.6E-55 T 12-10-2018 VAPA_1c01130 fd160305e9ec2b6efc7b8b97a83e2222 671 ProSitePatterns PS00455 Putative AMP-binding domain signature. 262 273 - T 12-10-2018 IPR020845 AMP-binding, conserved site VAPA_1c01130 fd160305e9ec2b6efc7b8b97a83e2222 671 TIGRFAM TIGR01217 ac_ac_CoA_syn: acetoacetate-CoA ligase 8 660 2.9E-208 T 12-10-2018 IPR005914 Acetoacetyl-CoA synthase GO:0006629|GO:0030729 KEGG: 00280+6.2.1.16|KEGG: 00650+6.2.1.16|Reactome: R-HSA-77111 VAPA_1c01130 fd160305e9ec2b6efc7b8b97a83e2222 671 Gene3D G3DSA:3.30.300.30 531 648 2.6E-11 T 12-10-2018 VAPA_1c01130 fd160305e9ec2b6efc7b8b97a83e2222 671 Pfam PF00501 AMP-binding enzyme 92 534 4.0E-46 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 VAPA_1c01130 fd160305e9ec2b6efc7b8b97a83e2222 671 SUPERFAMILY SSF56801 13 654 1.57E-118 T 12-10-2018 VAPA_1c11290 9d43d07c56617ff073ceac890bb0558c 177 Pfam PF04612 Type II secretion system (T2SS), protein M 6 147 4.3E-20 T 12-10-2018 IPR007690 Type II secretion system, protein M GO:0009306 VAPA_1c20300 069d6d39b98bd80ea8296b1452aad5dc 323 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 29 85 2.9E-7 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 VAPA_1c20300 069d6d39b98bd80ea8296b1452aad5dc 323 Pfam PF00107 Zinc-binding dehydrogenase 151 255 6.9E-26 T 12-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 VAPA_1c20300 069d6d39b98bd80ea8296b1452aad5dc 323 SUPERFAMILY SSF50129 3 144 7.76E-36 T 12-10-2018 IPR011032 GroES-like superfamily VAPA_1c20300 069d6d39b98bd80ea8296b1452aad5dc 323 Gene3D G3DSA:3.90.180.10 12 317 1.7E-105 T 12-10-2018 VAPA_1c20300 069d6d39b98bd80ea8296b1452aad5dc 323 Gene3D G3DSA:3.40.50.720 123 267 1.7E-105 T 12-10-2018 VAPA_1c20300 069d6d39b98bd80ea8296b1452aad5dc 323 SMART SM00829 11 321 1.3E-29 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 VAPA_1c20300 069d6d39b98bd80ea8296b1452aad5dc 323 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 140 161 - T 12-10-2018 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 VAPA_1c20300 069d6d39b98bd80ea8296b1452aad5dc 323 SUPERFAMILY SSF51735 111 274 1.56E-43 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c08230 e72b24f6d2ca4848437800267696f945 293 Gene3D G3DSA:3.90.25.10 157 251 7.8E-81 T 12-10-2018 VAPA_1c08230 e72b24f6d2ca4848437800267696f945 293 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 213 3.0E-42 T 12-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 VAPA_1c08230 e72b24f6d2ca4848437800267696f945 293 SUPERFAMILY SSF51735 2 284 4.96E-63 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c08230 e72b24f6d2ca4848437800267696f945 293 Gene3D G3DSA:3.40.50.720 3 264 7.8E-81 T 12-10-2018 VAPA_1c52940 019a618b21bbde4036851517063f853a 182 SUPERFAMILY SSF54593 8 146 3.99E-36 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase VAPA_1c52940 019a618b21bbde4036851517063f853a 182 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 13 142 7.1E-18 T 12-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain VAPA_1c52940 019a618b21bbde4036851517063f853a 182 Gene3D G3DSA:3.10.180.10 8 175 2.1E-37 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase VAPA_1c10960 9b92eefc355d3249e1e72ee708b4aea7 483 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 280 291 - T 12-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 VAPA_1c10960 9b92eefc355d3249e1e72ee708b4aea7 483 SUPERFAMILY SSF53720 7 479 4.19E-146 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 VAPA_1c10960 9b92eefc355d3249e1e72ee708b4aea7 483 Gene3D G3DSA:3.40.309.10 256 451 1.1E-150 T 12-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 VAPA_1c10960 9b92eefc355d3249e1e72ee708b4aea7 483 Gene3D G3DSA:3.40.605.10 27 478 1.1E-150 T 12-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 VAPA_1c10960 9b92eefc355d3249e1e72ee708b4aea7 483 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 252 259 - T 12-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 VAPA_1c10960 9b92eefc355d3249e1e72ee708b4aea7 483 Pfam PF00171 Aldehyde dehydrogenase family 23 478 1.3E-151 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 VAPA_1c18440 ea323fe782cc8cea6dd106b68e4e5daa 401 Gene3D G3DSA:3.30.1540.10 227 325 1.1E-114 T 12-10-2018 VAPA_1c18440 ea323fe782cc8cea6dd106b68e4e5daa 401 Gene3D G3DSA:3.40.50.10540 11 394 1.1E-114 T 12-10-2018 IPR023606 CoA-transferase family III domain superfamily VAPA_1c18440 ea323fe782cc8cea6dd106b68e4e5daa 401 SUPERFAMILY SSF89796 9 400 3.01E-121 T 12-10-2018 IPR023606 CoA-transferase family III domain superfamily VAPA_1c18440 ea323fe782cc8cea6dd106b68e4e5daa 401 Pfam PF02515 CoA-transferase family III 12 377 1.6E-115 T 12-10-2018 IPR003673 CoA-transferase family III GO:0003824 VAPA_1c49180 36016ad8c2435bf8f3c2c2ef7ffdd3d0 529 Pfam PF00795 Carbon-nitrogen hydrolase 272 490 4.1E-22 T 12-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 VAPA_1c49180 36016ad8c2435bf8f3c2c2ef7ffdd3d0 529 Gene3D G3DSA:3.60.110.10 264 500 6.2E-11 T 12-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily VAPA_1c49180 36016ad8c2435bf8f3c2c2ef7ffdd3d0 529 SUPERFAMILY SSF56317 244 501 2.88E-32 T 12-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily VAPA_1c49180 36016ad8c2435bf8f3c2c2ef7ffdd3d0 529 Hamap MF_01148 Apolipoprotein N-acyltransferase [lnt]. 19 514 20.242 T 12-10-2018 IPR004563 Apolipoprotein N-acyltransferase GO:0016021|GO:0016410|GO:0042158 VAPA_1c49180 36016ad8c2435bf8f3c2c2ef7ffdd3d0 529 TIGRFAM TIGR00546 lnt: apolipoprotein N-acyltransferase 81 472 6.9E-81 T 12-10-2018 IPR004563 Apolipoprotein N-acyltransferase GO:0016021|GO:0016410|GO:0042158 VAPA_1c45550 af10a82ff256994d17f40de6c7a94221 301 Hamap MF_00154 Protoheme IX farnesyltransferase [cyoE]. 15 299 19.243 T 12-10-2018 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 VAPA_1c45550 af10a82ff256994d17f40de6c7a94221 301 ProSitePatterns PS00943 UbiA prenyltransferase family signature. 73 95 - T 12-10-2018 IPR030470 UbiA prenyltransferase conserved site VAPA_1c45550 af10a82ff256994d17f40de6c7a94221 301 Gene3D G3DSA:1.10.357.140 26 181 5.1E-17 T 12-10-2018 VAPA_1c45550 af10a82ff256994d17f40de6c7a94221 301 TIGRFAM TIGR01473 cyoE_ctaB: protoheme IX farnesyltransferase 18 297 8.3E-95 T 12-10-2018 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 VAPA_1c45550 af10a82ff256994d17f40de6c7a94221 301 Pfam PF01040 UbiA prenyltransferase family 32 282 3.2E-63 T 12-10-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 VAPA_2c01800 0c5effd79efdf11d17e5569f7e2e6da6 185 Gene3D G3DSA:3.10.180.10 10 175 2.7E-27 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase VAPA_2c01800 0c5effd79efdf11d17e5569f7e2e6da6 185 SUPERFAMILY SSF54593 9 133 1.13E-23 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase VAPA_2c01800 0c5effd79efdf11d17e5569f7e2e6da6 185 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 10 126 1.3E-14 T 12-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain VAPA_1c49900 e4291e1fb0521c72c65001c6783c875f 260 Gene3D G3DSA:1.10.230.10 105 207 1.7E-21 T 12-10-2018 IPR016143 Citrate synthase-like, small alpha subdomain VAPA_1c49900 e4291e1fb0521c72c65001c6783c875f 260 SUPERFAMILY SSF48256 18 237 3.66E-40 T 12-10-2018 IPR036969 Citrate synthase superfamily GO:0046912 VAPA_1c49900 e4291e1fb0521c72c65001c6783c875f 260 Pfam PF00285 Citrate synthase, C-terminal domain 35 235 1.2E-24 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 VAPA_1c49900 e4291e1fb0521c72c65001c6783c875f 260 Gene3D G3DSA:1.10.580.10 34 233 1.7E-21 T 12-10-2018 IPR016142 Citrate synthase-like, large alpha subdomain Reactome: R-HSA-1268020|Reactome: R-HSA-71403 VAPA_1c24790 7f44554352bd6fcdc608964a36a340a1 149 SUPERFAMILY SSF53098 3 144 6.7E-56 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily VAPA_1c24790 7f44554352bd6fcdc608964a36a340a1 149 Gene3D G3DSA:3.30.420.10 2 147 1.1E-56 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 VAPA_1c24790 7f44554352bd6fcdc608964a36a340a1 149 Hamap MF_00042 Ribonuclease H [rnhA]. 1 149 31.02 T 12-10-2018 IPR022892 Ribonuclease HI GO:0004523 VAPA_1c24790 7f44554352bd6fcdc608964a36a340a1 149 Pfam PF00075 RNase H 3 142 2.1E-47 T 12-10-2018 IPR002156 Ribonuclease H domain GO:0003676|GO:0004523 VAPA_1c26920 9d4a915ea39d9aa586fe0a6c589e9271 325 Pfam PF07859 alpha/beta hydrolase fold 94 299 2.1E-68 T 12-10-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0016787 VAPA_1c26920 9d4a915ea39d9aa586fe0a6c589e9271 325 ProSitePatterns PS01173 Lipolytic enzymes "G-D-X-G" family, putative histidine active site. 94 110 - T 12-10-2018 IPR002168 Lipase, GDXG, putative histidine active site GO:0016787 Reactome: R-HSA-163560 VAPA_1c26920 9d4a915ea39d9aa586fe0a6c589e9271 325 SUPERFAMILY SSF53474 58 324 9.93E-67 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c26920 9d4a915ea39d9aa586fe0a6c589e9271 325 Gene3D G3DSA:3.40.50.1820 5 324 4.5E-86 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c25960 1220285f53963ae4c20d445bf9951bf7 230 SUPERFAMILY SSF52540 2 126 1.83E-7 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c10010 0d11946060632f8c21c85b5c88431b33 153 SUPERFAMILY SSF51230 78 153 3.66E-24 T 12-10-2018 IPR011053 Single hybrid motif VAPA_1c10010 0d11946060632f8c21c85b5c88431b33 153 Pfam PF00364 Biotin-requiring enzyme 79 152 1.4E-23 T 12-10-2018 IPR000089 Biotin/lipoyl attachment VAPA_1c10010 0d11946060632f8c21c85b5c88431b33 153 TIGRFAM TIGR00531 BCCP: acetyl-CoA carboxylase, biotin carboxyl carrier protein 1 153 1.6E-54 T 12-10-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 VAPA_1c10010 0d11946060632f8c21c85b5c88431b33 153 Gene3D G3DSA:2.40.50.100 76 153 6.7E-30 T 12-10-2018 VAPA_1c10010 0d11946060632f8c21c85b5c88431b33 153 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 99 113 2.2E-18 T 12-10-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 VAPA_1c10010 0d11946060632f8c21c85b5c88431b33 153 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 82 95 2.2E-18 T 12-10-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 VAPA_1c10010 0d11946060632f8c21c85b5c88431b33 153 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 114 127 2.2E-18 T 12-10-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 VAPA_1c42210 fe32472525db34e9ddf722e0f637aff9 249 Gene3D G3DSA:3.40.190.10 25 246 5.6E-72 T 12-10-2018 VAPA_1c42210 fe32472525db34e9ddf722e0f637aff9 249 TIGRFAM TIGR01256 modA: molybdate ABC transporter, periplasmic molybdate-binding protein 29 245 5.7E-60 T 12-10-2018 IPR005950 Molybdate ABC transporter, substrate-binding protein GO:0015689 VAPA_1c42210 fe32472525db34e9ddf722e0f637aff9 249 Gene3D G3DSA:3.40.190.10 103 209 5.6E-72 T 12-10-2018 VAPA_1c42210 fe32472525db34e9ddf722e0f637aff9 249 SUPERFAMILY SSF53850 22 247 5.12E-64 T 12-10-2018 VAPA_1c42210 fe32472525db34e9ddf722e0f637aff9 249 Pfam PF13531 Bacterial extracellular solute-binding protein 24 246 1.4E-46 T 12-10-2018 VAPA_1c42210 fe32472525db34e9ddf722e0f637aff9 249 PIRSF PIRSF004846 3 249 4.8E-75 T 12-10-2018 IPR005950 Molybdate ABC transporter, substrate-binding protein GO:0015689 VAPA_1c32060 f48494d76113b18d8a473d668403b581 476 TIGRFAM TIGR02485 CobZ_N-term: precorrin 3B synthase CobZ 1 460 7.4E-211 T 12-10-2018 IPR012831 Precorrin 3B synthase CobZ VAPA_1c32060 f48494d76113b18d8a473d668403b581 476 SUPERFAMILY SSF56425 264 401 3.84E-26 T 12-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 VAPA_1c32060 f48494d76113b18d8a473d668403b581 476 Pfam PF00890 FAD binding domain 3 432 6.6E-34 T 12-10-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 VAPA_1c32060 f48494d76113b18d8a473d668403b581 476 Gene3D G3DSA:3.50.50.60 3 455 3.1E-92 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c32060 f48494d76113b18d8a473d668403b581 476 SUPERFAMILY SSF51905 3 461 1.43E-40 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c32060 f48494d76113b18d8a473d668403b581 476 Gene3D G3DSA:3.90.700.10 236 397 3.1E-92 T 12-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 VAPA_1c33050 529414a18c3544700805b0efd11d53d0 449 SUPERFAMILY SSF56672 29 163 7.56E-7 T 12-10-2018 VAPA_1c09240 b56eaacdcff4105311516ba6c4d5292e 271 Gene3D G3DSA:1.10.1710.10 44 161 1.3E-21 T 12-10-2018 IPR036442 ProQ/FinO domain superfamily VAPA_1c09240 b56eaacdcff4105311516ba6c4d5292e 271 SMART SM00945 66 177 3.1E-38 T 12-10-2018 IPR016103 ProQ/FinO domain VAPA_1c09240 b56eaacdcff4105311516ba6c4d5292e 271 SUPERFAMILY SSF48657 55 166 1.26E-31 T 12-10-2018 IPR036442 ProQ/FinO domain superfamily VAPA_1c09240 b56eaacdcff4105311516ba6c4d5292e 271 Pfam PF04352 ProQ/FINO family 70 167 2.3E-26 T 12-10-2018 IPR016103 ProQ/FinO domain VAPA_2c08750 8e6344184fbedc28b6bdb4ff58ed63bc 273 Pfam PF12697 Alpha/beta hydrolase family 39 259 5.7E-20 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 VAPA_2c08750 8e6344184fbedc28b6bdb4ff58ed63bc 273 SUPERFAMILY SSF53474 32 263 2.81E-36 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_2c08750 8e6344184fbedc28b6bdb4ff58ed63bc 273 Gene3D G3DSA:3.40.50.1820 27 267 1.2E-45 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_2c01100 6825420df944ae3b7c8289e60080c471 147 PIRSF PIRSF018072 1 147 1.1E-42 T 12-10-2018 IPR016709 Uncharacterised protein family UPF0336 VAPA_2c01100 6825420df944ae3b7c8289e60080c471 147 Gene3D G3DSA:3.10.129.10 1 147 3.0E-40 T 12-10-2018 VAPA_2c01100 6825420df944ae3b7c8289e60080c471 147 Pfam PF13452 N-terminal half of MaoC dehydratase 6 137 3.2E-45 T 12-10-2018 IPR039569 N-terminal of MaoC-like dehydratase Reactome: R-HSA-193368|Reactome: R-HSA-2046106|Reactome: R-HSA-389887|Reactome: R-HSA-390247|Reactome: R-HSA-9033241|Reactome: R-HSA-9033500 VAPA_2c01100 6825420df944ae3b7c8289e60080c471 147 SUPERFAMILY SSF54637 6 146 1.33E-36 T 12-10-2018 IPR029069 HotDog domain superfamily VAPA_1c45400 10b8886525cec04c6ab82f73cb4e0eba 221 SMART SM00796 8 206 4.2E-101 T 12-10-2018 IPR003833 Carboxyltransferase domain, subdomain C and D VAPA_1c45400 10b8886525cec04c6ab82f73cb4e0eba 221 SUPERFAMILY SSF160467 9 96 1.83E-13 T 12-10-2018 VAPA_1c45400 10b8886525cec04c6ab82f73cb4e0eba 221 SUPERFAMILY SSF50891 92 218 2.73E-47 T 12-10-2018 IPR029000 Cyclophilin-like domain superfamily VAPA_1c45400 10b8886525cec04c6ab82f73cb4e0eba 221 Gene3D G3DSA:3.30.1360.40 9 81 2.1E-9 T 12-10-2018 VAPA_1c45400 10b8886525cec04c6ab82f73cb4e0eba 221 Pfam PF02682 Carboxyltransferase domain, subdomain C and D 9 206 5.4E-76 T 12-10-2018 IPR003833 Carboxyltransferase domain, subdomain C and D VAPA_1c45400 10b8886525cec04c6ab82f73cb4e0eba 221 TIGRFAM TIGR00370 TIGR00370: sensor histidine kinase inhibitor, KipI family 13 215 1.9E-79 T 12-10-2018 IPR010016 KipI family KEGG: 00480+3.5.2.9|MetaCyc: PWY-4041|MetaCyc: PWY-7942 VAPA_1c45400 10b8886525cec04c6ab82f73cb4e0eba 221 Gene3D G3DSA:2.40.100.10 91 221 1.9E-57 T 12-10-2018 IPR029000 Cyclophilin-like domain superfamily VAPA_1c09600 9665bd22bf48a29055c40f626fa8bec3 548 SUPERFAMILY SSF52091 461 543 8.63E-6 T 12-10-2018 IPR036513 STAS domain superfamily VAPA_1c48250 d9392e10c9e0d5257a0eeaffe35dda89 446 Gene3D G3DSA:2.70.70.10 282 410 5.6E-95 T 12-10-2018 IPR011055 Duplicated hybrid motif VAPA_1c48250 d9392e10c9e0d5257a0eeaffe35dda89 446 Gene3D G3DSA:3.10.450.350 75 159 2.4E-6 T 12-10-2018 VAPA_1c48250 d9392e10c9e0d5257a0eeaffe35dda89 446 Pfam PF01551 Peptidase family M23 310 404 2.0E-35 T 12-10-2018 IPR016047 Peptidase M23 VAPA_1c48250 d9392e10c9e0d5257a0eeaffe35dda89 446 Gene3D G3DSA:3.10.450.350 186 424 5.6E-95 T 12-10-2018 VAPA_1c48250 d9392e10c9e0d5257a0eeaffe35dda89 446 SUPERFAMILY SSF51261 179 405 1.83E-67 T 12-10-2018 IPR011055 Duplicated hybrid motif VAPA_2c02190 18993f4b35213b61cc3bc60e92b3ee13 323 SUPERFAMILY SSF53850 109 278 1.09E-12 T 12-10-2018 VAPA_2c02190 18993f4b35213b61cc3bc60e92b3ee13 323 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 49 319 6.0E-77 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_2c02190 18993f4b35213b61cc3bc60e92b3ee13 323 Gene3D G3DSA:3.40.190.150 30 313 1.2E-101 T 12-10-2018 VAPA_2c02190 18993f4b35213b61cc3bc60e92b3ee13 323 Gene3D G3DSA:3.40.190.10 127 249 1.2E-101 T 12-10-2018 VAPA_2c02190 18993f4b35213b61cc3bc60e92b3ee13 323 PIRSF PIRSF017082 1 322 1.7E-70 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c43520 45280981647decf92f3b907c64ca1dbf 248 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 172 244 4.6E-22 T 12-10-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain VAPA_1c43520 45280981647decf92f3b907c64ca1dbf 248 SUPERFAMILY SSF117143 79 206 2.22E-15 T 12-10-2018 IPR037925 Flagellar hook-basal body protein, FlgE/F/G-like VAPA_1c43520 45280981647decf92f3b907c64ca1dbf 248 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 4 122 5.3E-40 T 12-10-2018 IPR020013 Flagellar hook-basal body protein, FlgE/F/G VAPA_1c43520 45280981647decf92f3b907c64ca1dbf 248 Pfam PF00460 Flagella basal body rod protein 5 35 1.6E-7 T 12-10-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 VAPA_1c43520 45280981647decf92f3b907c64ca1dbf 248 ProSitePatterns PS00588 Flagella basal body rod proteins signature. 11 31 - T 12-10-2018 IPR019776 Flagellar basal body rod protein, conserved site VAPA_1c08620 df15dbdb8b0e9da876ff286d9f60064f 322 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 47 317 2.7E-97 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c08620 df15dbdb8b0e9da876ff286d9f60064f 322 Gene3D G3DSA:3.40.190.150 27 312 1.3E-119 T 12-10-2018 VAPA_1c08620 df15dbdb8b0e9da876ff286d9f60064f 322 SUPERFAMILY SSF53850 113 276 2.54E-13 T 12-10-2018 VAPA_1c08620 df15dbdb8b0e9da876ff286d9f60064f 322 PIRSF PIRSF017082 1 321 1.3E-82 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c08620 df15dbdb8b0e9da876ff286d9f60064f 322 Gene3D G3DSA:3.40.190.10 125 247 1.3E-119 T 12-10-2018 VAPA_1c19900 b495ae3c9fbe0a4b5f9dde3976092016 164 Gene3D G3DSA:3.40.50.2300 4 143 7.0E-39 T 12-10-2018 VAPA_1c19900 b495ae3c9fbe0a4b5f9dde3976092016 164 SUPERFAMILY SSF52788 6 144 1.57E-37 T 12-10-2018 IPR036196 Phosphotyrosine protein phosphatase I superfamily VAPA_1c19900 b495ae3c9fbe0a4b5f9dde3976092016 164 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 8 124 5.8E-17 T 12-10-2018 IPR023485 Phosphotyrosine protein phosphatase I VAPA_1c19900 b495ae3c9fbe0a4b5f9dde3976092016 164 SMART SM00226 6 144 6.6E-30 T 12-10-2018 IPR023485 Phosphotyrosine protein phosphatase I VAPA_1c25790 9afb31961d24f06f9d193e6302e839e9 276 Gene3D G3DSA:3.40.50.300 15 230 9.3E-63 T 12-10-2018 VAPA_1c25790 9afb31961d24f06f9d193e6302e839e9 276 SUPERFAMILY SSF52540 19 226 8.5E-64 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c25790 9afb31961d24f06f9d193e6302e839e9 276 SMART SM00382 43 217 1.1E-17 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c25790 9afb31961d24f06f9d193e6302e839e9 276 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_1c25790 9afb31961d24f06f9d193e6302e839e9 276 Pfam PF00005 ABC transporter 34 167 7.5E-31 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c16490 aa92274f50a0df297e66b8640e902dc0 299 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 27 73 6.6E-6 T 12-10-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain VAPA_1c16490 aa92274f50a0df297e66b8640e902dc0 299 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 114 296 2.9E-22 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 VAPA_1c16490 aa92274f50a0df297e66b8640e902dc0 299 Gene3D G3DSA:1.10.3720.10 88 292 1.8E-14 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c16490 aa92274f50a0df297e66b8640e902dc0 299 SUPERFAMILY SSF161098 94 277 1.44E-20 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c18540 0e5813484a4c5b88ffe98b6376a3047c 308 PRINTS PR01270 Histone deacetylase superfamily signature 225 235 3.1E-7 T 12-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 VAPA_1c18540 0e5813484a4c5b88ffe98b6376a3047c 308 PRINTS PR01270 Histone deacetylase superfamily signature 113 136 3.1E-7 T 12-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 VAPA_1c18540 0e5813484a4c5b88ffe98b6376a3047c 308 Gene3D G3DSA:3.40.800.20 10 298 1.4E-67 T 12-10-2018 IPR037138 Histone deacetylase domain superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 VAPA_1c18540 0e5813484a4c5b88ffe98b6376a3047c 308 Pfam PF00850 Histone deacetylase domain 22 283 9.8E-51 T 12-10-2018 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 VAPA_1c18540 0e5813484a4c5b88ffe98b6376a3047c 308 SUPERFAMILY SSF52768 4 282 4.41E-80 T 12-10-2018 IPR023696 Ureohydrolase domain superfamily VAPA_1c38660 799f400ba551feccce0283190317fbe4 722 Pfam PF07715 TonB-dependent Receptor Plug Domain 72 175 2.0E-26 T 12-10-2018 IPR012910 TonB-dependent receptor, plug domain VAPA_1c38660 799f400ba551feccce0283190317fbe4 722 Pfam PF00593 TonB dependent receptor 263 721 2.5E-66 T 12-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel VAPA_1c38660 799f400ba551feccce0283190317fbe4 722 Gene3D G3DSA:2.170.130.10 48 185 8.8E-44 T 12-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily VAPA_1c38660 799f400ba551feccce0283190317fbe4 722 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 73 721 1.1E-113 T 12-10-2018 IPR010105 TonB-dependent siderophore receptor GO:0005506|GO:0015891|GO:0038023 VAPA_1c38660 799f400ba551feccce0283190317fbe4 722 Gene3D G3DSA:2.40.170.20 186 722 2.6E-137 T 12-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily VAPA_1c38660 799f400ba551feccce0283190317fbe4 722 SUPERFAMILY SSF56935 34 722 2.08E-143 T 12-10-2018 VAPA_1c19180 717622087f66589d0c2899ba32c9ff9e 181 Gene3D G3DSA:2.20.25.120 47 79 2.5E-54 T 12-10-2018 VAPA_1c19180 717622087f66589d0c2899ba32c9ff9e 181 SUPERFAMILY SSF52540 1 116 1.92E-23 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c19180 717622087f66589d0c2899ba32c9ff9e 181 Pfam PF03205 Molybdopterin guanine dinucleotide synthesis protein B 3 140 5.2E-47 T 12-10-2018 IPR004435 Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB) domain GO:0005525|GO:0006777 VAPA_1c19180 717622087f66589d0c2899ba32c9ff9e 181 Gene3D G3DSA:3.40.50.300 4 166 2.5E-54 T 12-10-2018 VAPA_1c19180 717622087f66589d0c2899ba32c9ff9e 181 TIGRFAM TIGR00176 mobB: molybdopterin-guanine dinucleotide biosynthesis protein B 3 167 2.5E-44 T 12-10-2018 IPR004435 Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB) domain GO:0005525|GO:0006777 VAPA_1c30210 db54e84d5a3860cc6627b48657da9ecc 314 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 2.2E-19 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c30210 db54e84d5a3860cc6627b48657da9ecc 314 SUPERFAMILY SSF46785 3 111 5.45E-22 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c30210 db54e84d5a3860cc6627b48657da9ecc 314 Gene3D G3DSA:3.40.190.290 91 293 3.4E-68 T 12-10-2018 VAPA_1c30210 db54e84d5a3860cc6627b48657da9ecc 314 SUPERFAMILY SSF53850 90 295 1.99E-46 T 12-10-2018 VAPA_1c30210 db54e84d5a3860cc6627b48657da9ecc 314 Gene3D G3DSA:1.10.10.10 3 88 4.2E-26 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c30210 db54e84d5a3860cc6627b48657da9ecc 314 Pfam PF03466 LysR substrate binding domain 89 291 2.2E-44 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_2c12970 0386b790fc03c32f9c6cb265adcb65f0 223 Gene3D G3DSA:1.10.3720.10 2 219 5.6E-46 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_2c12970 0386b790fc03c32f9c6cb265adcb65f0 223 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 10 112 2.4E-17 T 12-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 VAPA_2c12970 0386b790fc03c32f9c6cb265adcb65f0 223 SUPERFAMILY SSF161098 9 215 7.06E-39 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_2c12970 0386b790fc03c32f9c6cb265adcb65f0 223 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 34 216 3.9E-22 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 VAPA_2c05380 a145d2215f68f7c09bff7cc1ee07b3ab 251 Gene3D G3DSA:3.40.50.150 17 223 5.0E-41 T 12-10-2018 VAPA_2c05380 a145d2215f68f7c09bff7cc1ee07b3ab 251 SUPERFAMILY SSF53335 14 209 6.39E-35 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase VAPA_2c05380 a145d2215f68f7c09bff7cc1ee07b3ab 251 Pfam PF01564 Spermine/spermidine synthase domain 47 177 5.5E-8 T 12-10-2018 VAPA_1c00910 c9d522492cbdd61de1484291213d4521 515 Pfam PF00501 AMP-binding enzyme 19 419 5.7E-96 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 VAPA_1c00910 c9d522492cbdd61de1484291213d4521 515 Gene3D G3DSA:3.40.50.980 1 240 6.0E-81 T 12-10-2018 VAPA_1c00910 c9d522492cbdd61de1484291213d4521 515 Gene3D G3DSA:1.10.10.2900 241 311 1.8E-29 T 12-10-2018 VAPA_1c00910 c9d522492cbdd61de1484291213d4521 515 Gene3D G3DSA:3.30.300.310 419 515 4.4E-31 T 12-10-2018 VAPA_1c00910 c9d522492cbdd61de1484291213d4521 515 TIGRFAM TIGR02262 benz_CoA_lig: benzoate-CoA ligase family 6 510 2.1E-242 T 12-10-2018 IPR011957 Benzoate-CoA ligase family GO:0005524|GO:0016405 VAPA_1c00910 c9d522492cbdd61de1484291213d4521 515 Pfam PF13193 AMP-binding enzyme C-terminal domain 427 502 1.6E-22 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain VAPA_1c00910 c9d522492cbdd61de1484291213d4521 515 SUPERFAMILY SSF56801 8 514 5.76E-151 T 12-10-2018 VAPA_1c00910 c9d522492cbdd61de1484291213d4521 515 Gene3D G3DSA:2.30.38.10 312 418 8.4E-40 T 12-10-2018 VAPA_1c11250 3565a5fcb38743bb00336f890eb72f99 411 Gene3D G3DSA:1.20.81.30 66 179 5.7E-26 T 12-10-2018 VAPA_1c11250 3565a5fcb38743bb00336f890eb72f99 411 Gene3D G3DSA:1.20.81.30 263 375 3.0E-23 T 12-10-2018 VAPA_1c11250 3565a5fcb38743bb00336f890eb72f99 411 Pfam PF00482 Type II secretion system (T2SS), protein F 280 402 3.0E-25 T 12-10-2018 IPR018076 Type II secretion system F domain VAPA_1c11250 3565a5fcb38743bb00336f890eb72f99 411 Pfam PF00482 Type II secretion system (T2SS), protein F 77 200 1.4E-31 T 12-10-2018 IPR018076 Type II secretion system F domain VAPA_1c11250 3565a5fcb38743bb00336f890eb72f99 411 PRINTS PR00812 Bacterial general secretion pathway protein F signature 73 85 7.2E-27 T 12-10-2018 IPR003004 GspF/PilC family VAPA_1c11250 3565a5fcb38743bb00336f890eb72f99 411 PRINTS PR00812 Bacterial general secretion pathway protein F signature 375 389 7.2E-27 T 12-10-2018 IPR003004 GspF/PilC family VAPA_1c11250 3565a5fcb38743bb00336f890eb72f99 411 PRINTS PR00812 Bacterial general secretion pathway protein F signature 172 200 7.2E-27 T 12-10-2018 IPR003004 GspF/PilC family VAPA_1c11250 3565a5fcb38743bb00336f890eb72f99 411 PRINTS PR00812 Bacterial general secretion pathway protein F signature 391 410 7.2E-27 T 12-10-2018 IPR003004 GspF/PilC family VAPA_1c11250 3565a5fcb38743bb00336f890eb72f99 411 TIGRFAM TIGR02120 GspF: type II secretion system protein F 4 410 1.2E-133 T 12-10-2018 IPR011850 General secretion pathway protein F GO:0008565|GO:0015627|GO:0015628 VAPA_2c01540 dd6626b9c68e7b53e5cb3bdf4e2711fc 164 Pfam PF12833 Helix-turn-helix domain 36 115 1.3E-24 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 VAPA_2c01540 dd6626b9c68e7b53e5cb3bdf4e2711fc 164 SUPERFAMILY SSF46689 66 116 2.46E-12 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 VAPA_2c01540 dd6626b9c68e7b53e5cb3bdf4e2711fc 164 Gene3D G3DSA:1.10.10.60 11 67 3.4E-10 T 12-10-2018 VAPA_2c01540 dd6626b9c68e7b53e5cb3bdf4e2711fc 164 Gene3D G3DSA:1.10.10.60 68 123 3.3E-14 T 12-10-2018 VAPA_2c01540 dd6626b9c68e7b53e5cb3bdf4e2711fc 164 SUPERFAMILY SSF46689 14 63 3.23E-10 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 VAPA_2c01540 dd6626b9c68e7b53e5cb3bdf4e2711fc 164 SMART SM00342 30 113 1.2E-27 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 VAPA_1c01110 4d6bffc9182859e70a6da1ff79de0cb6 314 Gene3D G3DSA:3.40.190.10 23 132 2.8E-12 T 12-10-2018 VAPA_1c01110 4d6bffc9182859e70a6da1ff79de0cb6 314 SUPERFAMILY SSF53850 28 253 4.4E-34 T 12-10-2018 VAPA_1c01110 4d6bffc9182859e70a6da1ff79de0cb6 314 Pfam PF09084 NMT1/THI5 like 39 249 2.4E-24 T 12-10-2018 IPR015168 SsuA/THI5-like VAPA_1c01110 4d6bffc9182859e70a6da1ff79de0cb6 314 Gene3D G3DSA:3.40.190.10 138 314 5.0E-25 T 12-10-2018 VAPA_1c29870 fa5ab99c4647faff15f907fa3d9c4985 349 Hamap MF_00230 Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase [cobT]. 14 346 33.988 T 12-10-2018 IPR017846 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, prokaryotic GO:0008939|GO:0009163 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970 VAPA_1c29870 fa5ab99c4647faff15f907fa3d9c4985 349 Gene3D G3DSA:1.10.1610.10 26 344 9.2E-118 T 12-10-2018 IPR023195 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, N-terminal GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970 VAPA_1c29870 fa5ab99c4647faff15f907fa3d9c4985 349 Pfam PF02277 Phosphoribosyltransferase 16 344 2.1E-121 T 12-10-2018 IPR003200 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970 VAPA_1c29870 fa5ab99c4647faff15f907fa3d9c4985 349 SUPERFAMILY SSF52733 20 346 1.03E-107 T 12-10-2018 IPR036087 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like superfamily GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970 VAPA_1c29870 fa5ab99c4647faff15f907fa3d9c4985 349 TIGRFAM TIGR03160 cobT_DBIPRT: nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 16 344 1.2E-127 T 12-10-2018 IPR017846 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, prokaryotic GO:0008939|GO:0009163 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970 VAPA_1c29870 fa5ab99c4647faff15f907fa3d9c4985 349 Gene3D G3DSA:3.40.50.10210 58 327 9.2E-118 T 12-10-2018 VAPA_2c08110 9835a0a4071023b9fc573e52d6fa6524 227 Pfam PF00857 Isochorismatase family 29 214 3.5E-34 T 12-10-2018 IPR000868 Isochorismatase-like GO:0003824 VAPA_2c08110 9835a0a4071023b9fc573e52d6fa6524 227 SUPERFAMILY SSF52499 21 220 7.72E-45 T 12-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 VAPA_2c08110 9835a0a4071023b9fc573e52d6fa6524 227 Gene3D G3DSA:3.40.50.850 9 217 1.4E-45 T 12-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 VAPA_1c03870 6ecffe0560f336c872b8545776615aa5 423 SUPERFAMILY SSF52540 73 362 6.83E-70 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c03870 6ecffe0560f336c872b8545776615aa5 423 Gene3D G3DSA:3.40.50.300 1 211 2.6E-75 T 12-10-2018 VAPA_1c03870 6ecffe0560f336c872b8545776615aa5 423 Gene3D G3DSA:3.40.50.300 216 372 3.4E-45 T 12-10-2018 VAPA_1c03870 6ecffe0560f336c872b8545776615aa5 423 Pfam PF00271 Helicase conserved C-terminal domain 235 340 1.6E-27 T 12-10-2018 IPR001650 Helicase, C-terminal VAPA_1c03870 6ecffe0560f336c872b8545776615aa5 423 Pfam PF00270 DEAD/DEAH box helicase 25 195 4.3E-47 T 12-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 VAPA_1c03870 6ecffe0560f336c872b8545776615aa5 423 SMART SM00487 20 223 6.1E-59 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain VAPA_1c03870 6ecffe0560f336c872b8545776615aa5 423 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 154 162 - T 12-10-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site VAPA_1c03870 6ecffe0560f336c872b8545776615aa5 423 SMART SM00490 259 340 4.8E-29 T 12-10-2018 IPR001650 Helicase, C-terminal VAPA_1c30930 b111369fa15b3971eae0c2eece9eeaf3 241 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 111 188 8.1E-7 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 VAPA_1c30930 b111369fa15b3971eae0c2eece9eeaf3 241 Pfam PF13419 Haloacid dehalogenase-like hydrolase 12 194 6.8E-26 T 12-10-2018 VAPA_1c30930 b111369fa15b3971eae0c2eece9eeaf3 241 SUPERFAMILY SSF56784 8 221 4.55E-49 T 12-10-2018 IPR036412 HAD-like superfamily VAPA_1c30930 b111369fa15b3971eae0c2eece9eeaf3 241 Gene3D G3DSA:1.10.150.240 24 94 1.3E-46 T 12-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 VAPA_1c30930 b111369fa15b3971eae0c2eece9eeaf3 241 Gene3D G3DSA:3.40.50.1000 12 199 1.3E-46 T 12-10-2018 IPR023214 HAD superfamily VAPA_1c09320 fec8eb471fa525aa83dc2d1e370a1b6d 493 Pfam PF02321 Outer membrane efflux protein 67 258 3.9E-23 T 12-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 VAPA_1c09320 fec8eb471fa525aa83dc2d1e370a1b6d 493 Pfam PF02321 Outer membrane efflux protein 289 466 1.4E-20 T 12-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 VAPA_1c09320 fec8eb471fa525aa83dc2d1e370a1b6d 493 Gene3D G3DSA:2.20.200.10 104 358 1.9E-113 T 12-10-2018 VAPA_1c09320 fec8eb471fa525aa83dc2d1e370a1b6d 493 Gene3D G3DSA:1.20.1600.10 57 470 1.9E-113 T 12-10-2018 VAPA_1c09320 fec8eb471fa525aa83dc2d1e370a1b6d 493 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 12 469 8.4E-79 T 12-10-2018 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0016020|GO:0022857|GO:0055085 VAPA_1c09320 fec8eb471fa525aa83dc2d1e370a1b6d 493 SUPERFAMILY SSF56954 5 473 5.36E-90 T 12-10-2018 VAPA_2c03460 1172b2a26765df507bbcde3ced12400e 169 SUPERFAMILY SSF53671 5 146 4.97E-16 T 12-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 VAPA_2c03460 1172b2a26765df507bbcde3ced12400e 169 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 10 146 6.3E-13 T 12-10-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 VAPA_2c03460 1172b2a26765df507bbcde3ced12400e 169 Gene3D G3DSA:3.40.50.1370 1 169 4.2E-25 T 12-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 VAPA_1c09970 af5b58b580cf312a51481d6c33f84d45 169 Pfam PF06172 Cupin superfamily (DUF985) 8 147 2.4E-44 T 12-10-2018 IPR009327 Cupin domain of unknown function DUF985 VAPA_1c09970 af5b58b580cf312a51481d6c33f84d45 169 SUPERFAMILY SSF51182 3 152 2.67E-51 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily VAPA_1c09970 af5b58b580cf312a51481d6c33f84d45 169 Gene3D G3DSA:2.60.120.10 1 164 3.6E-49 T 12-10-2018 IPR014710 RmlC-like jelly roll fold VAPA_1c35950 de302f77c6af069d54e796c00b4ad066 256 Pfam PF00005 ABC transporter 22 177 1.1E-27 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c35950 de302f77c6af069d54e796c00b4ad066 256 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 225 246 3.3E-8 T 12-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal VAPA_1c35950 de302f77c6af069d54e796c00b4ad066 256 SUPERFAMILY SSF52540 4 247 1.63E-61 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c35950 de302f77c6af069d54e796c00b4ad066 256 Gene3D G3DSA:3.40.50.300 3 253 4.4E-60 T 12-10-2018 VAPA_1c35950 de302f77c6af069d54e796c00b4ad066 256 SMART SM00382 30 224 7.2E-6 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c21760 185d61c283af6fe50e4838d1be534943 596 SUPERFAMILY SSF52518 25 194 8.84E-60 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold VAPA_1c21760 185d61c283af6fe50e4838d1be534943 596 SUPERFAMILY SSF52467 216 383 2.12E-57 T 12-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily VAPA_1c21760 185d61c283af6fe50e4838d1be534943 596 SUPERFAMILY SSF52518 394 592 4.83E-66 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold VAPA_1c21760 185d61c283af6fe50e4838d1be534943 596 Gene3D G3DSA:3.40.50.970 387 595 5.7E-71 T 12-10-2018 VAPA_1c21760 185d61c283af6fe50e4838d1be534943 596 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 453 472 - T 12-10-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 VAPA_1c21760 185d61c283af6fe50e4838d1be534943 596 Gene3D G3DSA:3.40.50.1220 213 381 1.0E-56 T 12-10-2018 VAPA_1c21760 185d61c283af6fe50e4838d1be534943 596 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 416 564 5.0E-50 T 12-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 VAPA_1c21760 185d61c283af6fe50e4838d1be534943 596 TIGRFAM TIGR00118 acolac_lg: acetolactate synthase, large subunit, biosynthetic type 27 586 1.1E-210 T 12-10-2018 IPR012846 Acetolactate synthase, large subunit, biosynthetic GO:0000287|GO:0003984|GO:0009082|GO:0030976|GO:0050660 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 VAPA_1c21760 185d61c283af6fe50e4838d1be534943 596 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 27 190 6.1E-58 T 12-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 VAPA_1c21760 185d61c283af6fe50e4838d1be534943 596 Gene3D G3DSA:3.40.50.970 19 199 2.2E-66 T 12-10-2018 VAPA_1c21760 185d61c283af6fe50e4838d1be534943 596 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 217 354 4.1E-42 T 12-10-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 VAPA_1c35200 ea6a1d1a8dcf12c704dc3736163b2063 327 SUPERFAMILY SSF51735 100 292 6.17E-57 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c35200 ea6a1d1a8dcf12c704dc3736163b2063 327 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 109 291 5.8E-56 T 12-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 VAPA_1c35200 ea6a1d1a8dcf12c704dc3736163b2063 327 Gene3D G3DSA:3.40.50.720 97 291 1.2E-101 T 12-10-2018 VAPA_1c35200 ea6a1d1a8dcf12c704dc3736163b2063 327 SUPERFAMILY SSF52283 4 133 1.1E-28 T 12-10-2018 VAPA_1c35200 ea6a1d1a8dcf12c704dc3736163b2063 327 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 7 319 1.6E-27 T 12-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 VAPA_1c35200 ea6a1d1a8dcf12c704dc3736163b2063 327 Gene3D G3DSA:3.40.50.720 7 318 1.2E-101 T 12-10-2018 VAPA_1c24810 7492981ab642b2aaae2bba2a118cf630 216 SUPERFAMILY SSF53448 14 213 2.92E-27 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases VAPA_1c24810 7492981ab642b2aaae2bba2a118cf630 216 Hamap MF_00316 Molybdenum cofactor guanylyltransferase [mobA]. 12 213 27.071 T 12-10-2018 IPR013482 Molybdenum cofactor guanylyltransferase GO:0003824|GO:0006777 KEGG: 00790+2.7.7.77|MetaCyc: PWY-5964|MetaCyc: PWY-7639 VAPA_1c24810 7492981ab642b2aaae2bba2a118cf630 216 Gene3D G3DSA:3.90.550.10 12 216 2.9E-46 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases VAPA_1c24810 7492981ab642b2aaae2bba2a118cf630 216 TIGRFAM TIGR02665 molyb_mobA: molybdenum cofactor guanylyltransferase 14 210 7.4E-64 T 12-10-2018 IPR013482 Molybdenum cofactor guanylyltransferase GO:0003824|GO:0006777 KEGG: 00790+2.7.7.77|MetaCyc: PWY-5964|MetaCyc: PWY-7639 VAPA_1c24810 7492981ab642b2aaae2bba2a118cf630 216 Pfam PF12804 MobA-like NTP transferase domain 16 179 1.9E-30 T 12-10-2018 IPR025877 MobA-like NTP transferase VAPA_1c12160 8e1e793af5f8393a48070d5baa2e976b 248 Pfam PF04333 MlaA lipoprotein 42 234 2.2E-72 T 12-10-2018 IPR007428 MlaA lipoprotein GO:0016020 VAPA_1c12160 8e1e793af5f8393a48070d5baa2e976b 248 PRINTS PR01805 VacJ lipoprotein signature 60 76 2.0E-24 T 12-10-2018 IPR007428 MlaA lipoprotein GO:0016020 VAPA_1c12160 8e1e793af5f8393a48070d5baa2e976b 248 PRINTS PR01805 VacJ lipoprotein signature 111 128 2.0E-24 T 12-10-2018 IPR007428 MlaA lipoprotein GO:0016020 VAPA_1c12160 8e1e793af5f8393a48070d5baa2e976b 248 PRINTS PR01805 VacJ lipoprotein signature 43 56 2.0E-24 T 12-10-2018 IPR007428 MlaA lipoprotein GO:0016020 VAPA_1c12160 8e1e793af5f8393a48070d5baa2e976b 248 PRINTS PR01805 VacJ lipoprotein signature 147 164 2.0E-24 T 12-10-2018 IPR007428 MlaA lipoprotein GO:0016020 VAPA_2c01450 41e6965cedd945cb5999589ea77b6e84 342 Gene3D G3DSA:3.20.20.140 1 341 2.7E-97 T 12-10-2018 VAPA_2c01450 41e6965cedd945cb5999589ea77b6e84 342 SUPERFAMILY SSF51556 1 333 2.14E-94 T 12-10-2018 IPR032466 Metal-dependent hydrolase VAPA_2c01450 41e6965cedd945cb5999589ea77b6e84 342 Pfam PF04909 Amidohydrolase 3 331 4.2E-57 T 12-10-2018 IPR006680 Amidohydrolase-related GO:0016787 VAPA_1c34810 5ecf076d411b0aa3b2147aefb6257210 302 SUPERFAMILY SSF52540 1 225 5.53E-60 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c34810 5ecf076d411b0aa3b2147aefb6257210 302 Gene3D G3DSA:3.40.50.300 1 233 6.2E-65 T 12-10-2018 VAPA_1c34810 5ecf076d411b0aa3b2147aefb6257210 302 SMART SM00382 28 211 1.3E-7 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c34810 5ecf076d411b0aa3b2147aefb6257210 302 Pfam PF00005 ABC transporter 19 162 1.1E-29 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c25810 a96a97a46c4f8cfa1f26e8f1afab2691 71 TIGRFAM TIGR00638 Mop: molybdenum-pterin binding domain 6 69 5.7E-19 T 12-10-2018 IPR004606 Molybdenum-pterin binding GO:0015689 VAPA_1c25810 a96a97a46c4f8cfa1f26e8f1afab2691 71 Gene3D G3DSA:2.40.50.100 5 70 1.5E-19 T 12-10-2018 VAPA_1c25810 a96a97a46c4f8cfa1f26e8f1afab2691 71 SUPERFAMILY SSF50331 6 69 1.29E-16 T 12-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal VAPA_1c25810 a96a97a46c4f8cfa1f26e8f1afab2691 71 Pfam PF03459 TOBE domain 8 67 3.1E-15 T 12-10-2018 IPR005116 Transport-associated OB, type 1 VAPA_1c31590 c7a869b14a3d113d8ae1b87ff0f9d34a 196 Gene3D G3DSA:1.25.40.10 30 173 8.1E-25 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 VAPA_1c31590 c7a869b14a3d113d8ae1b87ff0f9d34a 196 Pfam PF13432 Tetratricopeptide repeat 35 85 1.6E-6 T 12-10-2018 VAPA_1c31590 c7a869b14a3d113d8ae1b87ff0f9d34a 196 SUPERFAMILY SSF48452 33 153 7.59E-22 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 VAPA_1c31590 c7a869b14a3d113d8ae1b87ff0f9d34a 196 Pfam PF13414 TPR repeat 103 140 1.4E-10 T 12-10-2018 VAPA_1c31590 c7a869b14a3d113d8ae1b87ff0f9d34a 196 SMART SM00028 59 92 190.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 VAPA_1c31590 c7a869b14a3d113d8ae1b87ff0f9d34a 196 SMART SM00028 93 126 1.1E-6 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 VAPA_1c52210 f143d49c11544ddaf590174c4ed9caf8 341 SUPERFAMILY SSF52518 12 334 5.38E-81 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold VAPA_1c52210 f143d49c11544ddaf590174c4ed9caf8 341 Gene3D G3DSA:3.40.50.970 4 339 1.4E-103 T 12-10-2018 VAPA_1c52210 f143d49c11544ddaf590174c4ed9caf8 341 Pfam PF00676 Dehydrogenase E1 component 45 325 2.0E-60 T 12-10-2018 IPR001017 Dehydrogenase, E1 component GO:0016624 Reactome: R-HSA-389661 VAPA_1c35160 66f2ed8750f8b49317d087bc01e1eafb 288 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 106 274 7.9E-23 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 VAPA_1c35160 66f2ed8750f8b49317d087bc01e1eafb 288 SUPERFAMILY SSF161098 86 264 3.79E-21 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c35160 66f2ed8750f8b49317d087bc01e1eafb 288 Gene3D G3DSA:1.10.3720.10 83 281 4.1E-16 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c24100 2c4f38a34b90d798c8d2c6f687ff6937 202 Gene3D G3DSA:1.20.1050.10 78 201 4.9E-37 T 12-10-2018 VAPA_1c24100 2c4f38a34b90d798c8d2c6f687ff6937 202 Pfam PF13417 Glutathione S-transferase, N-terminal domain 3 72 8.9E-19 T 12-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 VAPA_1c24100 2c4f38a34b90d798c8d2c6f687ff6937 202 Gene3D G3DSA:3.40.30.10 1 76 1.1E-15 T 12-10-2018 VAPA_1c24100 2c4f38a34b90d798c8d2c6f687ff6937 202 SUPERFAMILY SSF52833 1 86 2.15E-14 T 12-10-2018 IPR036249 Thioredoxin-like superfamily VAPA_1c15350 9f3e951ab047fade48ae1b783160a88c 116 SUPERFAMILY SSF50037 31 106 9.16E-12 T 12-10-2018 IPR008988 Transcriptional repressor, C-terminal VAPA_1c15350 9f3e951ab047fade48ae1b783160a88c 116 Gene3D G3DSA:2.30.30.90 29 108 1.3E-21 T 12-10-2018 IPR038157 Ferrous iron transporter, core domain VAPA_1c15350 9f3e951ab047fade48ae1b783160a88c 116 SMART SM00899 29 107 1.3E-12 T 12-10-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 VAPA_1c15350 9f3e951ab047fade48ae1b783160a88c 116 Pfam PF04023 FeoA domain 30 106 2.3E-14 T 12-10-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 VAPA_1c06130 0787a420f00efba5b92bb0ce9100d2e2 792 Gene3D G3DSA:2.30.110.50 12 336 3.4E-76 T 12-10-2018 VAPA_1c06130 0787a420f00efba5b92bb0ce9100d2e2 792 Gene3D G3DSA:3.55.50.10 99 195 3.4E-76 T 12-10-2018 VAPA_1c06130 0787a420f00efba5b92bb0ce9100d2e2 792 SUPERFAMILY SSF69279 7 189 1.93E-41 T 12-10-2018 VAPA_1c06130 0787a420f00efba5b92bb0ce9100d2e2 792 SUPERFAMILY SSF69349 488 667 1.57E-43 T 12-10-2018 VAPA_1c06130 0787a420f00efba5b92bb0ce9100d2e2 792 Pfam PF05954 Phage late control gene D protein (GPD) 26 330 6.3E-64 T 12-10-2018 VAPA_1c06130 0787a420f00efba5b92bb0ce9100d2e2 792 SUPERFAMILY SSF69255 412 498 9.42E-35 T 12-10-2018 VAPA_1c06130 0787a420f00efba5b92bb0ce9100d2e2 792 TIGRFAM TIGR03361 VI_Rhs_Vgr: type VI secretion system Vgr family protein 393 567 2.1E-86 T 12-10-2018 IPR017847 Type VI secretion system, RhsGE-associated Vgr family subset VAPA_1c06130 0787a420f00efba5b92bb0ce9100d2e2 792 TIGRFAM TIGR03361 VI_Rhs_Vgr: type VI secretion system Vgr family protein 14 340 5.3E-56 T 12-10-2018 IPR017847 Type VI secretion system, RhsGE-associated Vgr family subset VAPA_1c06130 0787a420f00efba5b92bb0ce9100d2e2 792 Gene3D G3DSA:3.30.1920.30 230 292 3.4E-76 T 12-10-2018 VAPA_1c06130 0787a420f00efba5b92bb0ce9100d2e2 792 SUPERFAMILY SSF69349 633 774 4.24E-20 T 12-10-2018 VAPA_1c06130 0787a420f00efba5b92bb0ce9100d2e2 792 TIGRFAM TIGR01646 vgr_GE: Rhs element Vgr protein 22 331 2.7E-47 T 12-10-2018 IPR006533 Type VI secretion system, RhsGE-associated Vgr protein VAPA_1c06130 0787a420f00efba5b92bb0ce9100d2e2 792 TIGRFAM TIGR01646 vgr_GE: Rhs element Vgr protein 382 549 2.3E-62 T 12-10-2018 IPR006533 Type VI secretion system, RhsGE-associated Vgr protein VAPA_1c06130 0787a420f00efba5b92bb0ce9100d2e2 792 SUPERFAMILY SSF69279 199 410 1.87E-17 T 12-10-2018 VAPA_1c06130 0787a420f00efba5b92bb0ce9100d2e2 792 Gene3D G3DSA:2.40.50.230 401 503 3.5E-46 T 12-10-2018 IPR037026 Vgr protein, OB-fold domain superfamily VAPA_1c46180 170a17d097d0c1c306f5ee7f1c9bbfd6 190 Gene3D G3DSA:1.20.120.1220 27 146 2.1E-7 T 12-10-2018 VAPA_1c46180 170a17d097d0c1c306f5ee7f1c9bbfd6 190 Pfam PF01478 Type IV leader peptidase family 29 131 5.8E-18 T 12-10-2018 IPR000045 Prepilin type IV endopeptidase, peptidase domain GO:0004190|GO:0016020 VAPA_2c00890 60f46b5859009d7a1a7ee956b2415cd2 64 Gene3D G3DSA:3.20.20.70 1 63 7.3E-15 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 VAPA_2c00890 60f46b5859009d7a1a7ee956b2415cd2 64 SUPERFAMILY SSF51569 1 59 6.69E-16 T 12-10-2018 VAPA_2c00890 60f46b5859009d7a1a7ee956b2415cd2 64 Pfam PF00793 DAHP synthetase I family 1 55 3.9E-9 T 12-10-2018 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 VAPA_2c10350 0aceb981480f61a7575e2c041eba09f6 266 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 88 99 1.2E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c10350 0aceb981480f61a7575e2c041eba09f6 266 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 141 149 1.2E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c10350 0aceb981480f61a7575e2c041eba09f6 266 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 162 181 1.2E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c10350 0aceb981480f61a7575e2c041eba09f6 266 SUPERFAMILY SSF51735 6 263 2.63E-75 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_2c10350 0aceb981480f61a7575e2c041eba09f6 266 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 19 262 4.7E-63 T 12-10-2018 VAPA_2c10350 0aceb981480f61a7575e2c041eba09f6 266 Gene3D G3DSA:3.40.50.720 2 266 8.1E-84 T 12-10-2018 VAPA_2c10350 0aceb981480f61a7575e2c041eba09f6 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 14 31 3.6E-35 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c10350 0aceb981480f61a7575e2c041eba09f6 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 135 151 3.6E-35 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c10350 0aceb981480f61a7575e2c041eba09f6 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 225 245 3.6E-35 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c10350 0aceb981480f61a7575e2c041eba09f6 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 183 200 3.6E-35 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c10350 0aceb981480f61a7575e2c041eba09f6 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 88 99 3.6E-35 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c10350 0aceb981480f61a7575e2c041eba09f6 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 162 181 3.6E-35 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c13790 881bc5a9cec8f93281679a6296ef5b0e 296 Gene3D G3DSA:1.10.10.10 5 92 4.6E-20 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c13790 881bc5a9cec8f93281679a6296ef5b0e 296 SUPERFAMILY SSF53850 92 295 2.74E-45 T 12-10-2018 VAPA_1c13790 881bc5a9cec8f93281679a6296ef5b0e 296 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 9 66 4.3E-16 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c13790 881bc5a9cec8f93281679a6296ef5b0e 296 SUPERFAMILY SSF46785 3 115 3.02E-22 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c13790 881bc5a9cec8f93281679a6296ef5b0e 296 Pfam PF03466 LysR substrate binding domain 92 293 8.0E-44 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_1c13790 881bc5a9cec8f93281679a6296ef5b0e 296 Gene3D G3DSA:3.40.190.290 94 295 1.4E-41 T 12-10-2018 VAPA_1c42040 99c44ebd4c71dc2223665f4932ce1860 297 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 1.8E-16 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c42040 99c44ebd4c71dc2223665f4932ce1860 297 SUPERFAMILY SSF53850 88 293 4.16E-41 T 12-10-2018 VAPA_1c42040 99c44ebd4c71dc2223665f4932ce1860 297 SUPERFAMILY SSF46785 4 110 6.82E-20 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c42040 99c44ebd4c71dc2223665f4932ce1860 297 Gene3D G3DSA:3.40.190.10 90 289 7.4E-57 T 12-10-2018 VAPA_1c42040 99c44ebd4c71dc2223665f4932ce1860 297 Gene3D G3DSA:1.10.10.10 3 89 1.2E-25 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c42040 99c44ebd4c71dc2223665f4932ce1860 297 Pfam PF03466 LysR substrate binding domain 86 290 6.6E-40 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_1c42040 99c44ebd4c71dc2223665f4932ce1860 297 Gene3D G3DSA:3.40.190.10 161 263 7.4E-57 T 12-10-2018 VAPA_2c00050 e430206c6b01382324b464ca726f4718 218 Pfam PF00765 Autoinducer synthase 16 183 7.5E-18 T 12-10-2018 IPR001690 Autoinducer synthase GO:0016740 KEGG: 00270+2.3.1.184|MetaCyc: PWY-6157 VAPA_2c00050 e430206c6b01382324b464ca726f4718 218 PRINTS PR01549 Autoinducer synthesis protein signature 18 37 1.1E-15 T 12-10-2018 IPR001690 Autoinducer synthase GO:0016740 KEGG: 00270+2.3.1.184|MetaCyc: PWY-6157 VAPA_2c00050 e430206c6b01382324b464ca726f4718 218 PRINTS PR01549 Autoinducer synthesis protein signature 142 163 1.1E-15 T 12-10-2018 IPR001690 Autoinducer synthase GO:0016740 KEGG: 00270+2.3.1.184|MetaCyc: PWY-6157 VAPA_2c00050 e430206c6b01382324b464ca726f4718 218 PRINTS PR01549 Autoinducer synthesis protein signature 38 60 1.1E-15 T 12-10-2018 IPR001690 Autoinducer synthase GO:0016740 KEGG: 00270+2.3.1.184|MetaCyc: PWY-6157 VAPA_2c00050 e430206c6b01382324b464ca726f4718 218 PRINTS PR01549 Autoinducer synthesis protein signature 62 80 1.1E-15 T 12-10-2018 IPR001690 Autoinducer synthase GO:0016740 KEGG: 00270+2.3.1.184|MetaCyc: PWY-6157 VAPA_2c00050 e430206c6b01382324b464ca726f4718 218 PRINTS PR01549 Autoinducer synthesis protein signature 95 107 1.1E-15 T 12-10-2018 IPR001690 Autoinducer synthase GO:0016740 KEGG: 00270+2.3.1.184|MetaCyc: PWY-6157 VAPA_2c00050 e430206c6b01382324b464ca726f4718 218 ProSitePatterns PS00949 Autoinducer synthase family signature. 22 47 - T 12-10-2018 IPR018311 Autoinducer synthesis, conserved site KEGG: 00270+2.3.1.184|MetaCyc: PWY-6157 VAPA_2c00050 e430206c6b01382324b464ca726f4718 218 SUPERFAMILY SSF55729 11 181 2.62E-33 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase VAPA_2c00050 e430206c6b01382324b464ca726f4718 218 Gene3D G3DSA:3.40.630.30 2 192 5.4E-51 T 12-10-2018 VAPA_1c49960 30e5448734bd83abde1eeb8eb6c8c1cb 310 SUPERFAMILY SSF46689 13 82 2.15E-9 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 VAPA_1c49960 30e5448734bd83abde1eeb8eb6c8c1cb 310 Pfam PF01380 SIS domain 141 264 1.6E-17 T 12-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 VAPA_1c49960 30e5448734bd83abde1eeb8eb6c8c1cb 310 Pfam PF01418 Helix-turn-helix domain, rpiR family 12 74 8.2E-7 T 12-10-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 VAPA_1c49960 30e5448734bd83abde1eeb8eb6c8c1cb 310 Gene3D G3DSA:1.10.10.10 8 84 2.4E-9 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c49960 30e5448734bd83abde1eeb8eb6c8c1cb 310 Gene3D G3DSA:3.40.50.10490 104 289 2.3E-32 T 12-10-2018 VAPA_1c49960 30e5448734bd83abde1eeb8eb6c8c1cb 310 SUPERFAMILY SSF53697 114 276 1.68E-18 T 12-10-2018 VAPA_2c10660 600ffcac65d27e3f819e624c8f92af37 305 Gene3D G3DSA:1.10.10.60 200 304 3.1E-33 T 12-10-2018 VAPA_2c10660 600ffcac65d27e3f819e624c8f92af37 305 SUPERFAMILY SSF46689 254 301 2.54E-13 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 VAPA_2c10660 600ffcac65d27e3f819e624c8f92af37 305 Pfam PF12833 Helix-turn-helix domain 224 301 1.3E-24 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 VAPA_2c10660 600ffcac65d27e3f819e624c8f92af37 305 SUPERFAMILY SSF46689 203 250 4.66E-11 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 VAPA_2c10660 600ffcac65d27e3f819e624c8f92af37 305 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 254 296 - T 12-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 VAPA_2c10660 600ffcac65d27e3f819e624c8f92af37 305 SMART SM00342 217 300 2.5E-31 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 VAPA_2c03890 608f822a03acb0982d54e83028847013 412 Pfam PF12704 MacB-like periplasmic core domain 23 257 5.9E-16 T 12-10-2018 IPR025857 MacB-like periplasmic core domain VAPA_2c03890 608f822a03acb0982d54e83028847013 412 Pfam PF02687 FtsX-like permease family 312 406 5.5E-11 T 12-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 VAPA_1c34080 ff39f4e3231809cbbd4fb8b09988207c 392 SUPERFAMILY SSF103025 12 288 1.54E-81 T 12-10-2018 VAPA_1c34080 ff39f4e3231809cbbd4fb8b09988207c 392 TIGRFAM TIGR00528 gcvT: glycine cleavage system T protein 14 386 2.6E-96 T 12-10-2018 IPR006223 Glycine cleavage system T protein GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 VAPA_1c34080 ff39f4e3231809cbbd4fb8b09988207c 392 PIRSF PIRSF006487 1 392 1.6E-68 T 12-10-2018 IPR028896 Aminomethyltransferase-like KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 VAPA_1c34080 ff39f4e3231809cbbd4fb8b09988207c 392 SUPERFAMILY SSF101790 304 391 4.58E-23 T 12-10-2018 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal VAPA_1c34080 ff39f4e3231809cbbd4fb8b09988207c 392 Pfam PF01571 Aminomethyltransferase folate-binding domain 18 264 4.7E-82 T 12-10-2018 IPR006222 Aminomethyltransferase, folate-binding domain VAPA_1c34080 ff39f4e3231809cbbd4fb8b09988207c 392 Gene3D G3DSA:3.30.70.1400 64 148 4.3E-76 T 12-10-2018 VAPA_1c34080 ff39f4e3231809cbbd4fb8b09988207c 392 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 303 380 7.2E-16 T 12-10-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 VAPA_1c34080 ff39f4e3231809cbbd4fb8b09988207c 392 Gene3D G3DSA:2.40.30.110 305 381 3.2E-25 T 12-10-2018 VAPA_1c34080 ff39f4e3231809cbbd4fb8b09988207c 392 Gene3D G3DSA:4.10.1250.10 242 290 2.9E-21 T 12-10-2018 VAPA_1c34080 ff39f4e3231809cbbd4fb8b09988207c 392 Gene3D G3DSA:3.30.1360.120 15 241 4.3E-76 T 12-10-2018 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 VAPA_1c01040 5a8d7f89f588c158aaed5b7452549b41 302 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 252 274 6.6E-9 T 12-10-2018 VAPA_1c01040 5a8d7f89f588c158aaed5b7452549b41 302 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 6.6E-9 T 12-10-2018 VAPA_1c01040 5a8d7f89f588c158aaed5b7452549b41 302 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 104 112 4.8E-13 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 VAPA_1c01040 5a8d7f89f588c158aaed5b7452549b41 302 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 4 26 4.8E-13 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 VAPA_1c01040 5a8d7f89f588c158aaed5b7452549b41 302 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 262 280 4.8E-13 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 VAPA_1c01040 5a8d7f89f588c158aaed5b7452549b41 302 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 126 138 4.8E-13 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 VAPA_1c01040 5a8d7f89f588c158aaed5b7452549b41 302 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 178 284 8.9E-7 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 VAPA_1c01040 5a8d7f89f588c158aaed5b7452549b41 302 SUPERFAMILY SSF51905 1 296 6.49E-29 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c01040 5a8d7f89f588c158aaed5b7452549b41 302 Gene3D G3DSA:3.50.50.60 117 228 7.6E-87 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c01040 5a8d7f89f588c158aaed5b7452549b41 302 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 4 136 1.4E-6 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 VAPA_1c01040 5a8d7f89f588c158aaed5b7452549b41 302 Gene3D G3DSA:3.50.50.60 3 293 7.6E-87 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c34430 974995030640f2b580a9be974424c58b 409 Gene3D G3DSA:3.30.420.40 229 372 1.0E-17 T 12-10-2018 VAPA_1c34430 974995030640f2b580a9be974424c58b 409 Gene3D G3DSA:1.10.10.10 15 91 1.9E-15 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c34430 974995030640f2b580a9be974424c58b 409 Pfam PF00480 ROK family 98 392 1.0E-22 T 12-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 VAPA_1c34430 974995030640f2b580a9be974424c58b 409 SUPERFAMILY SSF53067 96 396 1.05E-31 T 12-10-2018 VAPA_1c34430 974995030640f2b580a9be974424c58b 409 SUPERFAMILY SSF46785 24 91 1.84E-11 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c34430 974995030640f2b580a9be974424c58b 409 Gene3D G3DSA:3.30.420.40 92 228 3.9E-16 T 12-10-2018 VAPA_1c09780 06c4300ec00a935bf10fbfcc4bfe93a1 329 SUPERFAMILY SSF54211 25 147 3.11E-39 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold VAPA_1c09780 06c4300ec00a935bf10fbfcc4bfe93a1 329 Gene3D G3DSA:3.30.1700.10 150 328 2.0E-64 T 12-10-2018 IPR011334 UDP-3-O-acyl N-acetylglucosamine deacetylase, C-terminal GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108 VAPA_1c09780 06c4300ec00a935bf10fbfcc4bfe93a1 329 SUPERFAMILY SSF54211 166 302 7.59E-48 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold VAPA_1c09780 06c4300ec00a935bf10fbfcc4bfe93a1 329 Pfam PF03331 UDP-3-O-acyl N-acetylglycosamine deacetylase 26 301 1.8E-103 T 12-10-2018 IPR004463 UDP-3-O-acyl N-acetylglucosamine deacetylase GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108 VAPA_1c09780 06c4300ec00a935bf10fbfcc4bfe93a1 329 Hamap MF_00388 UDP-3-O-acyl-N-acetylglucosamine deacetylase [lpxC]. 24 305 44.38 T 12-10-2018 IPR004463 UDP-3-O-acyl N-acetylglucosamine deacetylase GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108 VAPA_1c09780 06c4300ec00a935bf10fbfcc4bfe93a1 329 TIGRFAM TIGR00325 lpxC: UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase 25 322 2.2E-111 T 12-10-2018 IPR004463 UDP-3-O-acyl N-acetylglucosamine deacetylase GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108 VAPA_1c09780 06c4300ec00a935bf10fbfcc4bfe93a1 329 Gene3D G3DSA:3.30.230.20 23 149 2.5E-46 T 12-10-2018 IPR015870 UDP-3-O-acyl N-acetylglucosamine deacetylase, N-terminal GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108 VAPA_2c10440 0ae659ad393468d5081e7d7aa88c6b7c 421 SUPERFAMILY SSF53822 28 393 4.89E-48 T 12-10-2018 IPR028082 Periplasmic binding protein-like I VAPA_2c10440 0ae659ad393468d5081e7d7aa88c6b7c 421 Gene3D G3DSA:3.40.50.2300 288 378 2.4E-6 T 12-10-2018 VAPA_2c10440 0ae659ad393468d5081e7d7aa88c6b7c 421 Gene3D G3DSA:3.40.50.2300 25 168 9.1E-19 T 12-10-2018 VAPA_2c10440 0ae659ad393468d5081e7d7aa88c6b7c 421 Pfam PF13458 Periplasmic binding protein 29 389 8.6E-40 T 12-10-2018 IPR028081 Leucine-binding protein domain VAPA_2c10440 0ae659ad393468d5081e7d7aa88c6b7c 421 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 73 91 8.0E-6 T 12-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 VAPA_2c10440 0ae659ad393468d5081e7d7aa88c6b7c 421 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 354 369 8.0E-6 T 12-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 VAPA_2c10440 0ae659ad393468d5081e7d7aa88c6b7c 421 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 30 46 8.0E-6 T 12-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 VAPA_2c10440 0ae659ad393468d5081e7d7aa88c6b7c 421 Gene3D G3DSA:3.40.50.2300 169 287 7.2E-14 T 12-10-2018 VAPA_1c48100 799d8ec4ead5adcdf4b8b949e5ad19c2 353 SUPERFAMILY SSF56935 20 353 4.71E-65 T 12-10-2018 VAPA_1c48100 799d8ec4ead5adcdf4b8b949e5ad19c2 353 Gene3D G3DSA:2.40.160.10 20 353 7.5E-75 T 12-10-2018 IPR023614 Porin domain superfamily VAPA_1c48100 799d8ec4ead5adcdf4b8b949e5ad19c2 353 Pfam PF13609 Gram-negative porin 7 314 2.1E-45 T 12-10-2018 VAPA_1c09930 2d0eb8e537ed4374b5c30dae94b375bb 384 TIGRFAM TIGR02210 rodA_shape: rod shape-determining protein RodA 22 379 6.4E-123 T 12-10-2018 IPR011923 Probable peptidoglycan glycosyltransferase RodA/MrdB GO:0008360|GO:0016021 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 VAPA_1c09930 2d0eb8e537ed4374b5c30dae94b375bb 384 Pfam PF01098 Cell cycle protein 27 380 4.3E-95 T 12-10-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 VAPA_1c09930 2d0eb8e537ed4374b5c30dae94b375bb 384 ProSitePatterns PS00428 Cell cycle proteins ftsW / rodA / spoVE signature. 337 361 - T 12-10-2018 IPR018365 Cell cycle, FtsW / RodA / SpoVE, conserved site GO:0016021 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 VAPA_1c09930 2d0eb8e537ed4374b5c30dae94b375bb 384 Hamap MF_02079 Peptidoglycan glycosyltransferase MrdB [mrdB]. 16 382 26.331 T 12-10-2018 IPR011923 Probable peptidoglycan glycosyltransferase RodA/MrdB GO:0008360|GO:0016021 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 VAPA_1c25920 c9bbfa7ac5fc015284e6dfce7c7bd0c5 295 TIGRFAM TIGR02139 permease_CysT: sulfate ABC transporter, permease protein CysT 28 291 1.1E-127 T 12-10-2018 IPR011865 Sulphate ABC transporter, permease protein CysT GO:0008272|GO:0015116|GO:0016021 VAPA_1c25920 c9bbfa7ac5fc015284e6dfce7c7bd0c5 295 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 95 292 8.2E-27 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 VAPA_1c25920 c9bbfa7ac5fc015284e6dfce7c7bd0c5 295 Gene3D G3DSA:1.10.3720.10 32 293 2.1E-69 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c25920 c9bbfa7ac5fc015284e6dfce7c7bd0c5 295 SUPERFAMILY SSF161098 34 283 6.92E-55 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c25920 c9bbfa7ac5fc015284e6dfce7c7bd0c5 295 TIGRFAM TIGR00969 3a0106s02: sulfate ABC transporter, permease protein 27 287 8.8E-98 T 12-10-2018 IPR005667 Sulphate ABC transporter permease protein 2 GO:0008272|GO:0015419|GO:0016020 VAPA_2c06510 d81dc8b67cabd1d6c9159ee040702941 736 SUPERFAMILY SSF63380 517 598 4.15E-15 T 12-10-2018 IPR017938 Riboflavin synthase-like beta-barrel VAPA_2c06510 d81dc8b67cabd1d6c9159ee040702941 736 Pfam PF03929 PepSY-associated TM region 4 315 6.6E-34 T 12-10-2018 IPR005625 PepSY-associated TM protein VAPA_2c06510 d81dc8b67cabd1d6c9159ee040702941 736 Gene3D G3DSA:3.40.50.360 324 477 1.3E-28 T 12-10-2018 IPR029039 Flavoprotein-like superfamily VAPA_2c06510 d81dc8b67cabd1d6c9159ee040702941 736 Pfam PF00258 Flavodoxin 336 463 4.0E-17 T 12-10-2018 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 VAPA_2c06510 d81dc8b67cabd1d6c9159ee040702941 736 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 671 687 1.3E-11 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 VAPA_2c06510 d81dc8b67cabd1d6c9159ee040702941 736 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 531 541 1.3E-11 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 VAPA_2c06510 d81dc8b67cabd1d6c9159ee040702941 736 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 606 625 1.3E-11 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 VAPA_2c06510 d81dc8b67cabd1d6c9159ee040702941 736 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 641 652 1.3E-11 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 VAPA_2c06510 d81dc8b67cabd1d6c9159ee040702941 736 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 548 555 1.3E-11 T 12-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 VAPA_2c06510 d81dc8b67cabd1d6c9159ee040702941 736 SUPERFAMILY SSF52218 321 478 7.5E-35 T 12-10-2018 IPR029039 Flavoprotein-like superfamily VAPA_2c06510 d81dc8b67cabd1d6c9159ee040702941 736 Gene3D G3DSA:2.40.30.10 519 589 9.6E-8 T 12-10-2018 VAPA_2c06510 d81dc8b67cabd1d6c9159ee040702941 736 Pfam PF00175 Oxidoreductase NAD-binding domain 607 708 1.4E-11 T 12-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 VAPA_2c06510 d81dc8b67cabd1d6c9159ee040702941 736 SUPERFAMILY SSF52343 598 736 6.81E-31 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain VAPA_2c06510 d81dc8b67cabd1d6c9159ee040702941 736 Gene3D G3DSA:3.40.50.80 596 736 8.8E-33 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain VAPA_1c32310 6e2e745c814700759da3a21d9c7f4289 304 TIGRFAM TIGR03409 urea_trans_UrtB: urea ABC transporter, permease protein UrtB 12 303 3.3E-117 T 12-10-2018 IPR017779 ABC transporter, urea permease protein UrtB, bacterial-type VAPA_1c32310 6e2e745c814700759da3a21d9c7f4289 304 Pfam PF02653 Branched-chain amino acid transport system / permease component 15 290 2.3E-42 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 VAPA_2c03700 a49f3c032e2528ac032c2ffe9546c983 521 Gene3D G3DSA:3.30.300.30 413 516 1.7E-26 T 12-10-2018 VAPA_2c03700 a49f3c032e2528ac032c2ffe9546c983 521 Gene3D G3DSA:3.40.50.12780 12 411 6.1E-111 T 12-10-2018 VAPA_2c03700 a49f3c032e2528ac032c2ffe9546c983 521 ProSitePatterns PS00455 Putative AMP-binding domain signature. 170 181 - T 12-10-2018 IPR020845 AMP-binding, conserved site VAPA_2c03700 a49f3c032e2528ac032c2ffe9546c983 521 Pfam PF13193 AMP-binding enzyme C-terminal domain 427 502 5.0E-18 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain VAPA_2c03700 a49f3c032e2528ac032c2ffe9546c983 521 SUPERFAMILY SSF56801 13 512 3.92E-140 T 12-10-2018 VAPA_2c03700 a49f3c032e2528ac032c2ffe9546c983 521 Pfam PF00501 AMP-binding enzyme 23 418 2.1E-97 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 VAPA_1c25080 7d29dfae0db08b41950e0235b27c4df5 163 SUPERFAMILY SSF55021 79 162 3.34E-25 T 12-10-2018 VAPA_1c25080 7d29dfae0db08b41950e0235b27c4df5 163 SUPERFAMILY SSF55021 1 76 2.1E-22 T 12-10-2018 VAPA_1c25080 7d29dfae0db08b41950e0235b27c4df5 163 Pfam PF13710 ACT domain 12 73 1.6E-15 T 12-10-2018 VAPA_1c25080 7d29dfae0db08b41950e0235b27c4df5 163 TIGRFAM TIGR00119 acolac_sm: acetolactate synthase, small subunit 1 157 7.7E-63 T 12-10-2018 IPR004789 Acetolactate synthase, small subunit GO:0003984|GO:0009082 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 VAPA_1c25080 7d29dfae0db08b41950e0235b27c4df5 163 Gene3D G3DSA:3.30.70.1150 83 163 1.6E-29 T 12-10-2018 IPR027271 Acetolactate synthase/Transcription factor NikR, C-terminal VAPA_1c25080 7d29dfae0db08b41950e0235b27c4df5 163 Pfam PF10369 Small subunit of acetolactate synthase 84 157 9.1E-27 T 12-10-2018 IPR019455 Acetolactate synthase, small subunit, C-terminal KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 VAPA_1c25080 7d29dfae0db08b41950e0235b27c4df5 163 ProDom PD002844 SMALL SUBUNIT ACETOLACTATE SYNTHASE SYNTHASE TRANSFERASE ACID BIOSYNTHESIS III LYASE 1 76 7.0E-36 T 12-10-2018 VAPA_1c25080 7d29dfae0db08b41950e0235b27c4df5 163 Gene3D G3DSA:3.30.70.260 1 78 1.9E-35 T 12-10-2018 VAPA_1c47740 1deee84865afc8f732e1efddff86d636 78 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 40 57 1.4E-9 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 VAPA_1c47740 1deee84865afc8f732e1efddff86d636 78 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 57 77 1.4E-9 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 VAPA_1c47740 1deee84865afc8f732e1efddff86d636 78 PIRSF PIRSF002097 1 77 2.8E-30 T 12-10-2018 IPR005412 DNA-binding protein Fis GO:0003677|GO:0006355 VAPA_1c47740 1deee84865afc8f732e1efddff86d636 78 Pfam PF02954 Bacterial regulatory protein, Fis family 35 71 2.7E-12 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 VAPA_1c47740 1deee84865afc8f732e1efddff86d636 78 SUPERFAMILY SSF46689 8 76 3.0E-19 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 VAPA_1c47740 1deee84865afc8f732e1efddff86d636 78 Gene3D G3DSA:1.10.10.60 1 76 1.4E-22 T 12-10-2018 VAPA_1c01960 669028d6a29c9fc9f7418c9cd3e62353 267 SUPERFAMILY SSF55781 103 266 2.16E-31 T 12-10-2018 VAPA_1c01960 669028d6a29c9fc9f7418c9cd3e62353 267 SUPERFAMILY SSF46785 35 98 1.54E-12 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c01960 669028d6a29c9fc9f7418c9cd3e62353 267 Pfam PF09339 IclR helix-turn-helix domain 35 80 1.5E-9 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 VAPA_1c01960 669028d6a29c9fc9f7418c9cd3e62353 267 Gene3D G3DSA:3.30.450.40 100 262 5.0E-40 T 12-10-2018 IPR029016 GAF-like domain superfamily VAPA_1c01960 669028d6a29c9fc9f7418c9cd3e62353 267 SMART SM00346 35 119 2.0E-9 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 VAPA_1c01960 669028d6a29c9fc9f7418c9cd3e62353 267 Gene3D G3DSA:1.10.10.10 34 99 5.8E-14 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c01960 669028d6a29c9fc9f7418c9cd3e62353 267 Pfam PF01614 Bacterial transcriptional regulator 148 263 5.1E-10 T 12-10-2018 IPR014757 Transcription regulator IclR, C-terminal VAPA_2c02020 073ed301b5cd9f0d592608b163e073b3 474 SUPERFAMILY SSF56954 1 448 4.05E-51 T 12-10-2018 VAPA_2c02020 073ed301b5cd9f0d592608b163e073b3 474 Gene3D G3DSA:1.20.1600.10 71 451 4.6E-37 T 12-10-2018 VAPA_2c02020 073ed301b5cd9f0d592608b163e073b3 474 Pfam PF02321 Outer membrane efflux protein 72 243 1.5E-13 T 12-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 VAPA_2c02020 073ed301b5cd9f0d592608b163e073b3 474 Pfam PF02321 Outer membrane efflux protein 272 447 6.1E-11 T 12-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 VAPA_1c24840 1ec0c8dd5aaf34044c85c575bd5fbf30 184 SUPERFAMILY SSF52833 25 177 1.56E-34 T 12-10-2018 IPR036249 Thioredoxin-like superfamily VAPA_1c24840 1ec0c8dd5aaf34044c85c575bd5fbf30 184 Gene3D G3DSA:3.40.30.10 22 178 6.5E-31 T 12-10-2018 VAPA_1c24840 1ec0c8dd5aaf34044c85c575bd5fbf30 184 Pfam PF00578 AhpC/TSA family 28 156 2.8E-21 T 12-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 VAPA_1c40200 6616329324c82bd5d5fef58c4c539194 390 Pfam PF02608 ABC transporter substrate-binding protein PnrA-like 57 321 1.1E-51 T 12-10-2018 IPR003760 ABC transporter substrate-binding protein PnrA-like GO:0005886 VAPA_1c40200 6616329324c82bd5d5fef58c4c539194 390 Gene3D G3DSA:3.40.50.2300 160 376 7.1E-126 T 12-10-2018 VAPA_1c40200 6616329324c82bd5d5fef58c4c539194 390 Gene3D G3DSA:3.40.50.2300 58 313 7.1E-126 T 12-10-2018 VAPA_1c53640 48651d26dd652085e68224cf02e9382e 248 TIGRFAM TIGR03717 R_switched_YjbE: integral membrane protein, YjbE family 12 192 1.8E-73 T 12-10-2018 IPR022301 Integral membrane protein YjbE VAPA_1c53640 48651d26dd652085e68224cf02e9382e 248 Pfam PF03741 Integral membrane protein TerC family 15 190 2.4E-48 T 12-10-2018 IPR005496 Integral membrane protein TerC GO:0016021 VAPA_1c20810 93a342015f9ee39f2d5a7a0b6eb6e55d 339 Gene3D G3DSA:3.40.190.170 31 339 3.9E-103 T 12-10-2018 IPR038404 TRAP transporter solute receptor DctP superfamily VAPA_1c20810 93a342015f9ee39f2d5a7a0b6eb6e55d 339 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 39 312 3.5E-68 T 12-10-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0030288|GO:0055085 VAPA_1c20810 93a342015f9ee39f2d5a7a0b6eb6e55d 339 PIRSF PIRSF006470 4 334 2.1E-70 T 12-10-2018 IPR004682 TRAP transporter solute receptor, DctP family GO:0030288|GO:0055085 VAPA_1c20810 93a342015f9ee39f2d5a7a0b6eb6e55d 339 TIGRFAM TIGR00787 dctP: TRAP transporter solute receptor, DctP family 39 293 3.0E-72 T 12-10-2018 IPR004682 TRAP transporter solute receptor, DctP family GO:0030288|GO:0055085 VAPA_1c40690 f725984ddb0d768a67e680b570cde378 239 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 74 85 2.5E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c40690 f725984ddb0d768a67e680b570cde378 239 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 144 163 2.5E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c40690 f725984ddb0d768a67e680b570cde378 239 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 124 132 2.5E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c40690 f725984ddb0d768a67e680b570cde378 239 SUPERFAMILY SSF51735 9 238 1.39E-67 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c40690 f725984ddb0d768a67e680b570cde378 239 Gene3D G3DSA:3.40.50.720 2 238 1.9E-69 T 12-10-2018 VAPA_1c40690 f725984ddb0d768a67e680b570cde378 239 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 12 29 9.4E-38 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c40690 f725984ddb0d768a67e680b570cde378 239 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 74 85 9.4E-38 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c40690 f725984ddb0d768a67e680b570cde378 239 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 165 182 9.4E-38 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c40690 f725984ddb0d768a67e680b570cde378 239 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 118 134 9.4E-38 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c40690 f725984ddb0d768a67e680b570cde378 239 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 144 163 9.4E-38 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c40690 f725984ddb0d768a67e680b570cde378 239 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 200 220 9.4E-38 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c40690 f725984ddb0d768a67e680b570cde378 239 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 17 236 1.2E-52 T 12-10-2018 VAPA_1c40690 f725984ddb0d768a67e680b570cde378 239 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 131 159 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 VAPA_2c05770 17ac7dac1277eb973bfb4827e519004d 316 Gene3D G3DSA:3.30.390.50 223 316 1.2E-26 T 12-10-2018 VAPA_2c05770 17ac7dac1277eb973bfb4827e519004d 316 Gene3D G3DSA:3.30.465.10 1 222 1.8E-86 T 12-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 VAPA_2c05770 17ac7dac1277eb973bfb4827e519004d 316 SMART SM01092 226 314 1.1E-20 T 12-10-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal VAPA_2c05770 17ac7dac1277eb973bfb4827e519004d 316 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 3 220 1.3E-50 T 12-10-2018 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 VAPA_2c05770 17ac7dac1277eb973bfb4827e519004d 316 SUPERFAMILY SSF55447 224 315 2.09E-20 T 12-10-2018 IPR036683 CO dehydrogenase flavoprotein, C-terminal domain superfamily VAPA_2c05770 17ac7dac1277eb973bfb4827e519004d 316 SUPERFAMILY SSF56176 1 220 2.51E-60 T 12-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 VAPA_2c05770 17ac7dac1277eb973bfb4827e519004d 316 Pfam PF03450 CO dehydrogenase flavoprotein C-terminal domain 227 300 1.8E-7 T 12-10-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal VAPA_1c10440 c503dcf1509bce46b760430a4bf41289 227 SUPERFAMILY SSF52833 3 90 1.75E-20 T 12-10-2018 IPR036249 Thioredoxin-like superfamily VAPA_1c10440 c503dcf1509bce46b760430a4bf41289 227 Gene3D G3DSA:3.40.30.10 4 207 5.5E-57 T 12-10-2018 VAPA_1c10440 c503dcf1509bce46b760430a4bf41289 227 SUPERFAMILY SSF47616 87 209 5.68E-17 T 12-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily VAPA_1c10440 c503dcf1509bce46b760430a4bf41289 227 Pfam PF13417 Glutathione S-transferase, N-terminal domain 10 85 1.8E-13 T 12-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 VAPA_1c10440 c503dcf1509bce46b760430a4bf41289 227 Gene3D G3DSA:1.20.1050.10 87 200 5.5E-57 T 12-10-2018 VAPA_1c39230 6a9ea7c97d6d18b8126fc84bf2f767f4 725 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 23 133 1.1E-23 T 12-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead VAPA_1c39230 6a9ea7c97d6d18b8126fc84bf2f767f4 725 SUPERFAMILY SSF56003 127 723 5.76E-155 T 12-10-2018 IPR037165 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain superfamily GO:0016491|GO:0055114 VAPA_1c39230 6a9ea7c97d6d18b8126fc84bf2f767f4 725 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 161 662 9.8E-118 T 12-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 VAPA_1c39230 6a9ea7c97d6d18b8126fc84bf2f767f4 725 Gene3D G3DSA:3.30.365.10 1 725 8.0E-175 T 12-10-2018 VAPA_1c39230 6a9ea7c97d6d18b8126fc84bf2f767f4 725 SUPERFAMILY SSF54665 6 141 1.83E-36 T 12-10-2018 IPR036856 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead superfamily VAPA_1c39230 6a9ea7c97d6d18b8126fc84bf2f767f4 725 SMART SM01008 23 135 5.7E-37 T 12-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead VAPA_2c10060 98b14a8480540cffe6a8b1e854ab7b73 218 Pfam PF01872 RibD C-terminal domain 8 198 2.8E-22 T 12-10-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 VAPA_2c10060 98b14a8480540cffe6a8b1e854ab7b73 218 SUPERFAMILY SSF53597 8 199 2.1E-26 T 12-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 VAPA_2c10060 98b14a8480540cffe6a8b1e854ab7b73 218 Gene3D G3DSA:3.40.430.10 2 214 1.6E-46 T 12-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 VAPA_1c43340 2abf605d7141d1bf415016d484acff28 161 Pfam PF04347 Flagellar biosynthesis protein, FliO 65 153 7.9E-21 T 12-10-2018 IPR022781 Flagellar biosynthesis protein, FliO GO:0016021|GO:0044781 VAPA_1c43340 2abf605d7141d1bf415016d484acff28 161 TIGRFAM TIGR03500 FliO_TIGR: flagellar biosynthetic protein FliO 54 120 4.0E-22 T 12-10-2018 IPR022781 Flagellar biosynthesis protein, FliO GO:0016021|GO:0044781 VAPA_1c50180 8b7aa5666aade44bd95f3728cde620b7 510 Gene3D G3DSA:3.40.50.300 2 237 4.9E-51 T 12-10-2018 VAPA_1c50180 8b7aa5666aade44bd95f3728cde620b7 510 Pfam PF00005 ABC transporter 278 435 1.1E-9 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c50180 8b7aa5666aade44bd95f3728cde620b7 510 Gene3D G3DSA:3.40.50.300 261 506 2.8E-33 T 12-10-2018 VAPA_1c50180 8b7aa5666aade44bd95f3728cde620b7 510 SUPERFAMILY SSF52540 261 490 5.64E-32 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c50180 8b7aa5666aade44bd95f3728cde620b7 510 Pfam PF00005 ABC transporter 21 172 3.5E-25 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c50180 8b7aa5666aade44bd95f3728cde620b7 510 ProSitePatterns PS00211 ABC transporters family signature. 412 426 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_1c50180 8b7aa5666aade44bd95f3728cde620b7 510 SUPERFAMILY SSF52540 4 227 6.32E-50 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c50180 8b7aa5666aade44bd95f3728cde620b7 510 SMART SM00382 29 228 2.5E-6 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c09470 d0e6375516a1915daae4a6d11ba31b0c 400 Pfam PF07690 Major Facilitator Superfamily 9 319 5.1E-40 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 VAPA_1c09470 d0e6375516a1915daae4a6d11ba31b0c 400 Gene3D G3DSA:1.20.1250.20 3 377 1.6E-52 T 12-10-2018 VAPA_1c09470 d0e6375516a1915daae4a6d11ba31b0c 400 PRINTS PR01035 Tetracycline resistance protein signature 98 119 2.7E-5 T 12-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 VAPA_1c09470 d0e6375516a1915daae4a6d11ba31b0c 400 PRINTS PR01035 Tetracycline resistance protein signature 158 178 2.7E-5 T 12-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 VAPA_1c09470 d0e6375516a1915daae4a6d11ba31b0c 400 PRINTS PR01035 Tetracycline resistance protein signature 40 59 2.7E-5 T 12-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 VAPA_1c09470 d0e6375516a1915daae4a6d11ba31b0c 400 PRINTS PR01035 Tetracycline resistance protein signature 10 26 2.7E-5 T 12-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 VAPA_1c09470 d0e6375516a1915daae4a6d11ba31b0c 400 SUPERFAMILY SSF103473 3 380 6.93E-63 T 12-10-2018 IPR036259 MFS transporter superfamily VAPA_2c01830 de3efe20ecb9950f71069882fabf329c 192 Pfam PF06684 Amino acid synthesis 6 178 6.4E-68 T 12-10-2018 IPR009569 Amino acid synthesis, putative VAPA_2c01830 de3efe20ecb9950f71069882fabf329c 192 Gene3D G3DSA:3.30.1330.110 1 192 6.5E-80 T 12-10-2018 IPR035936 BB2672 superfamily VAPA_2c01830 de3efe20ecb9950f71069882fabf329c 192 SUPERFAMILY SSF160519 3 192 8.24E-72 T 12-10-2018 IPR035936 BB2672 superfamily VAPA_1c18070 8007d9a5a5f15871042aff4889adb263 364 Pfam PF10282 Lactonase, 7-bladed beta-propeller 36 359 6.6E-83 T 12-10-2018 IPR019405 Lactonase, 7-bladed beta propeller VAPA_1c18070 8007d9a5a5f15871042aff4889adb263 364 Gene3D G3DSA:2.130.10.10 28 363 7.9E-112 T 12-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 VAPA_1c18070 8007d9a5a5f15871042aff4889adb263 364 SUPERFAMILY SSF51004 15 363 8.89E-42 T 12-10-2018 IPR011048 Cytochrome cd1-nitrite reductase-like, haem d1 domain superfamily VAPA_1c42090 36be4055e78793ecc89377ce31eb8aa2 290 Pfam PF02634 FdhD/NarQ family 39 278 3.2E-75 T 12-10-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 VAPA_1c42090 36be4055e78793ecc89377ce31eb8aa2 290 SUPERFAMILY SSF53927 21 279 6.62E-65 T 12-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 VAPA_1c42090 36be4055e78793ecc89377ce31eb8aa2 290 Hamap MF_00187 Sulfur carrier protein FdhD [fdhD]. 17 279 25.415 T 12-10-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 VAPA_1c42090 36be4055e78793ecc89377ce31eb8aa2 290 Gene3D G3DSA:3.40.140.10 127 286 3.8E-36 T 12-10-2018 VAPA_1c42090 36be4055e78793ecc89377ce31eb8aa2 290 PIRSF PIRSF015626 9 283 2.0E-71 T 12-10-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 VAPA_1c42090 36be4055e78793ecc89377ce31eb8aa2 290 Gene3D G3DSA:3.10.20.10 40 122 1.3E-8 T 12-10-2018 VAPA_1c39340 83ed89656c053a43c83a47709012c75d 330 Gene3D G3DSA:1.10.1530.10 9 327 3.3E-91 T 12-10-2018 VAPA_1c39340 83ed89656c053a43c83a47709012c75d 330 Gene3D G3DSA:3.30.60.50 175 225 3.3E-91 T 12-10-2018 VAPA_1c39340 83ed89656c053a43c83a47709012c75d 330 Gene3D G3DSA:3.30.1370.60 59 301 3.3E-91 T 12-10-2018 VAPA_1c39340 83ed89656c053a43c83a47709012c75d 330 Pfam PF02615 Malate/L-lactate dehydrogenase 3 327 3.1E-94 T 12-10-2018 IPR003767 Malate/L-lactate dehydrogenase-like GO:0016491|GO:0055114 VAPA_1c39340 83ed89656c053a43c83a47709012c75d 330 SUPERFAMILY SSF89733 2 328 2.49E-92 T 12-10-2018 IPR036111 Malate/L-sulfolactate/L-lactate dehydrogenase-like superfamily GO:0016491|GO:0055114 VAPA_1c09560 fa4805b5b559a1b9c6440ff82d015802 406 Gene3D G3DSA:3.40.50.150 176 405 3.1E-62 T 12-10-2018 VAPA_1c09560 fa4805b5b559a1b9c6440ff82d015802 406 SUPERFAMILY SSF53335 89 400 9.24E-59 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase VAPA_1c09560 fa4805b5b559a1b9c6440ff82d015802 406 Gene3D G3DSA:2.30.130.10 2 69 2.5E-22 T 12-10-2018 IPR036974 PUA domain superfamily GO:0003723 VAPA_1c09560 fa4805b5b559a1b9c6440ff82d015802 406 Gene3D G3DSA:3.30.750.80 70 175 7.5E-32 T 12-10-2018 VAPA_1c09560 fa4805b5b559a1b9c6440ff82d015802 406 Pfam PF10672 S-adenosylmethionine-dependent methyltransferase 166 360 2.9E-20 T 12-10-2018 IPR019614 S-adenosylmethionine-dependent methyltransferase GO:0008168 VAPA_1c09560 fa4805b5b559a1b9c6440ff82d015802 406 SUPERFAMILY SSF88697 1 65 5.8E-11 T 12-10-2018 IPR015947 PUA-like superfamily VAPA_2c10250 295af1096f2483802927a7fc2d5452da 340 Gene3D G3DSA:3.40.190.10 178 282 1.7E-26 T 12-10-2018 VAPA_2c10250 295af1096f2483802927a7fc2d5452da 340 SUPERFAMILY SSF53850 99 308 3.94E-19 T 12-10-2018 VAPA_2c10250 295af1096f2483802927a7fc2d5452da 340 Gene3D G3DSA:1.10.10.10 11 99 1.1E-17 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_2c10250 295af1096f2483802927a7fc2d5452da 340 Gene3D G3DSA:3.40.190.10 112 299 1.7E-26 T 12-10-2018 VAPA_2c10250 295af1096f2483802927a7fc2d5452da 340 Pfam PF03466 LysR substrate binding domain 99 300 2.6E-17 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_2c10250 295af1096f2483802927a7fc2d5452da 340 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 40 1.6E-7 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_2c10250 295af1096f2483802927a7fc2d5452da 340 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 50 61 1.6E-7 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_2c10250 295af1096f2483802927a7fc2d5452da 340 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 50 1.6E-7 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_2c10250 295af1096f2483802927a7fc2d5452da 340 SUPERFAMILY SSF46785 13 98 1.3E-14 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_2c10250 295af1096f2483802927a7fc2d5452da 340 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 14 69 2.7E-13 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_2c00120 b19e88cccbec7f4524b3cd9cbdf432f8 234 Pfam PF03483 B3/4 domain 64 197 8.7E-23 T 12-10-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 VAPA_2c00120 b19e88cccbec7f4524b3cd9cbdf432f8 234 SMART SM00873 63 210 2.5E-8 T 12-10-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 VAPA_2c00120 b19e88cccbec7f4524b3cd9cbdf432f8 234 Gene3D G3DSA:3.50.40.10 66 214 1.0E-9 T 12-10-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 KEGG: 00970+6.1.1.20 VAPA_2c00120 b19e88cccbec7f4524b3cd9cbdf432f8 234 SUPERFAMILY SSF56037 59 199 5.23E-30 T 12-10-2018 VAPA_1c01910 99e980c1015e000b33754fb3a5ab6dc4 517 Hamap MF_00229 Histidine ammonia-lyase [hutH]. 10 511 43.452 T 12-10-2018 IPR005921 Histidine ammonia-lyase GO:0004397|GO:0005737|GO:0006548 KEGG: 00340+4.3.1.3|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 VAPA_1c01910 99e980c1015e000b33754fb3a5ab6dc4 517 Pfam PF00221 Aromatic amino acid lyase 20 478 1.5E-181 T 12-10-2018 IPR001106 Aromatic amino acid lyase Reactome: R-HSA-70921 VAPA_1c01910 99e980c1015e000b33754fb3a5ab6dc4 517 ProSitePatterns PS00488 Phenylalanine and histidine ammonia-lyases signature. 146 161 - T 12-10-2018 IPR022313 Phenylalanine/histidine ammonia-lyases, active site GO:0016841 Reactome: R-HSA-70921 VAPA_1c01910 99e980c1015e000b33754fb3a5ab6dc4 517 SUPERFAMILY SSF48557 7 506 2.9E-188 T 12-10-2018 IPR008948 L-Aspartase-like GO:0003824 VAPA_1c01910 99e980c1015e000b33754fb3a5ab6dc4 517 Gene3D G3DSA:1.20.200.10 206 512 4.9E-117 T 12-10-2018 VAPA_1c01910 99e980c1015e000b33754fb3a5ab6dc4 517 Gene3D G3DSA:1.10.275.10 9 205 7.8E-64 T 12-10-2018 IPR024083 Fumarase/histidase, N-terminal VAPA_1c01910 99e980c1015e000b33754fb3a5ab6dc4 517 TIGRFAM TIGR01225 hutH: histidine ammonia-lyase 12 509 4.7E-205 T 12-10-2018 IPR005921 Histidine ammonia-lyase GO:0004397|GO:0005737|GO:0006548 KEGG: 00340+4.3.1.3|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 VAPA_1c28630 c7fd8e14c64b5bc8dd681a063298c7f8 241 Gene3D G3DSA:3.30.70.980 130 205 1.6E-54 T 12-10-2018 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 VAPA_1c28630 c7fd8e14c64b5bc8dd681a063298c7f8 241 TIGRFAM TIGR01033 TIGR01033: DNA-binding regulatory protein, YebC/PmpR family 1 237 3.5E-92 T 12-10-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 VAPA_1c28630 c7fd8e14c64b5bc8dd681a063298c7f8 241 Pfam PF01709 Transcriptional regulator 5 237 3.8E-92 T 12-10-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 VAPA_1c28630 c7fd8e14c64b5bc8dd681a063298c7f8 241 Gene3D G3DSA:3.30.70.980 86 236 1.6E-54 T 12-10-2018 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 VAPA_1c28630 c7fd8e14c64b5bc8dd681a063298c7f8 241 Gene3D G3DSA:1.10.10.200 1 81 2.4E-30 T 12-10-2018 IPR017856 Integrase-like, N-terminal VAPA_1c28630 c7fd8e14c64b5bc8dd681a063298c7f8 241 SUPERFAMILY SSF75625 3 240 1.7E-94 T 12-10-2018 IPR029072 YebC-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 VAPA_1c28630 c7fd8e14c64b5bc8dd681a063298c7f8 241 Hamap MF_00693 Probable transcriptional regulatory protein YebC [yebC]. 3 239 34.88 T 12-10-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 VAPA_2c07910 efbf7632c84dce2e5fc1b5d07241d6e8 340 Pfam PF00589 Phage integrase family 176 320 6.5E-6 T 12-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 VAPA_2c07910 efbf7632c84dce2e5fc1b5d07241d6e8 340 Gene3D G3DSA:1.10.443.10 166 332 4.0E-13 T 12-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 VAPA_2c07910 efbf7632c84dce2e5fc1b5d07241d6e8 340 SUPERFAMILY SSF56349 141 321 5.3E-17 T 12-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 VAPA_1c16660 93dea974dabe099cb6171c65c817ec90 618 SUPERFAMILY SSF52518 5 375 8.85E-80 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold VAPA_1c16660 93dea974dabe099cb6171c65c817ec90 618 Gene3D G3DSA:3.40.50.920 489 614 2.6E-44 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 VAPA_1c16660 93dea974dabe099cb6171c65c817ec90 618 Pfam PF02779 Transketolase, pyrimidine binding domain 313 472 1.3E-40 T 12-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain VAPA_1c16660 93dea974dabe099cb6171c65c817ec90 618 Pfam PF13292 1-deoxy-D-xylulose-5-phosphate synthase 6 276 1.9E-120 T 12-10-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 VAPA_1c16660 93dea974dabe099cb6171c65c817ec90 618 TIGRFAM TIGR00204 dxs: 1-deoxy-D-xylulose-5-phosphate synthase 8 611 3.0E-265 T 12-10-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 VAPA_1c16660 93dea974dabe099cb6171c65c817ec90 618 SUPERFAMILY SSF52518 312 498 1.14E-59 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold VAPA_1c16660 93dea974dabe099cb6171c65c817ec90 618 SMART SM00861 313 477 1.9E-69 T 12-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain VAPA_1c16660 93dea974dabe099cb6171c65c817ec90 618 ProSitePatterns PS00801 Transketolase signature 1. 30 49 - T 12-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 VAPA_1c16660 93dea974dabe099cb6171c65c817ec90 618 SUPERFAMILY SSF52922 486 613 2.36E-33 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 VAPA_1c16660 93dea974dabe099cb6171c65c817ec90 618 Gene3D G3DSA:3.40.50.970 311 483 1.3E-68 T 12-10-2018 VAPA_1c16660 93dea974dabe099cb6171c65c817ec90 618 Pfam PF02780 Transketolase, C-terminal domain 489 605 6.9E-28 T 12-10-2018 IPR033248 Transketolase, C-terminal domain VAPA_1c16660 93dea974dabe099cb6171c65c817ec90 618 ProSitePatterns PS00802 Transketolase signature 2. 419 435 - T 12-10-2018 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 VAPA_1c16660 93dea974dabe099cb6171c65c817ec90 618 Hamap MF_00315 1-deoxy-D-xylulose-5-phosphate synthase [dxs]. 4 614 46.274 T 12-10-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 VAPA_1c51760 654e62bdd152b4eb36b020419571087a 394 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 232 376 3.4E-11 T 12-10-2018 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-5633231 VAPA_1c51760 654e62bdd152b4eb36b020419571087a 394 Pfam PF06925 Monogalactosyldiacylglycerol (MGDG) synthase 30 197 5.9E-23 T 12-10-2018 IPR009695 Diacylglycerol glucosyltransferase, N-terminal GO:0009247|GO:0016758 VAPA_1c51760 654e62bdd152b4eb36b020419571087a 394 SUPERFAMILY SSF53756 110 390 1.26E-36 T 12-10-2018 VAPA_1c51760 654e62bdd152b4eb36b020419571087a 394 Gene3D G3DSA:3.40.50.2000 210 376 9.4E-35 T 12-10-2018 VAPA_2c08610 a8e3c417ecb022d52532dbdbb34eb6b8 597 TIGRFAM TIGR03075 PQQ_enz_alc_DH: PQQ-dependent dehydrogenase, methanol/ethanol family 21 551 5.7E-226 T 12-10-2018 IPR017512 PQQ-dependent dehydrogenase, methanol/ethanol family GO:0005509|GO:0016020|GO:0016614|GO:0055114 VAPA_2c08610 a8e3c417ecb022d52532dbdbb34eb6b8 597 Pfam PF01011 PQQ enzyme repeat 498 533 5.5E-9 T 12-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat VAPA_2c08610 a8e3c417ecb022d52532dbdbb34eb6b8 597 SUPERFAMILY SSF50998 33 574 2.49E-155 T 12-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily VAPA_2c08610 a8e3c417ecb022d52532dbdbb34eb6b8 597 Pfam PF13360 PQQ-like domain 68 308 2.0E-17 T 12-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat VAPA_2c08610 a8e3c417ecb022d52532dbdbb34eb6b8 597 SMART SM00564 179 216 10.0 T 12-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat VAPA_2c08610 a8e3c417ecb022d52532dbdbb34eb6b8 597 SMART SM00564 133 165 0.002 T 12-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat VAPA_2c08610 a8e3c417ecb022d52532dbdbb34eb6b8 597 SMART SM00564 283 310 57.0 T 12-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat VAPA_2c08610 a8e3c417ecb022d52532dbdbb34eb6b8 597 SMART SM00564 85 116 7.5E-5 T 12-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat VAPA_2c08610 a8e3c417ecb022d52532dbdbb34eb6b8 597 SMART SM00564 440 482 0.12 T 12-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat VAPA_2c08610 a8e3c417ecb022d52532dbdbb34eb6b8 597 SMART SM00564 491 523 0.0016 T 12-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat VAPA_2c08610 a8e3c417ecb022d52532dbdbb34eb6b8 597 Gene3D G3DSA:2.140.10.10 22 581 9.7E-205 T 12-10-2018 VAPA_1c06880 3c0cef7d40d3d93bc79c6d79a618b421 252 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 224 246 2.6E-9 T 12-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal VAPA_1c06880 3c0cef7d40d3d93bc79c6d79a618b421 252 SUPERFAMILY SSF52540 5 247 1.52E-56 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c06880 3c0cef7d40d3d93bc79c6d79a618b421 252 Pfam PF00005 ABC transporter 22 177 1.7E-24 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c06880 3c0cef7d40d3d93bc79c6d79a618b421 252 SMART SM00382 30 232 4.5E-8 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c06880 3c0cef7d40d3d93bc79c6d79a618b421 252 Gene3D G3DSA:3.40.50.300 3 251 1.5E-53 T 12-10-2018 VAPA_1c19630 4895af90b8dc20a1b80d51bf33b1aafc 142 Pfam PF06094 Gamma-glutamyl cyclotransferase, AIG2-like 19 136 4.9E-23 T 12-10-2018 IPR009288 Gamma-glutamylcyclotransferase, AIG2-like VAPA_1c19630 4895af90b8dc20a1b80d51bf33b1aafc 142 Gene3D G3DSA:3.10.490.10 16 139 2.8E-26 T 12-10-2018 VAPA_1c19630 4895af90b8dc20a1b80d51bf33b1aafc 142 SUPERFAMILY SSF110857 18 138 8.37E-25 T 12-10-2018 IPR036568 Gamma-glutamyl cyclotransferase-like superfamily VAPA_1c29100 8db3a07972a643843f2b92e16281c932 146 Pfam PF02472 Biopolymer transport protein ExbD/TolR 13 139 3.2E-26 T 12-10-2018 IPR003400 Biopolymer transport protein ExbD/TolR GO:0022857|GO:0055085 VAPA_1c29100 8db3a07972a643843f2b92e16281c932 146 Gene3D G3DSA:3.30.420.270 65 136 2.5E-9 T 12-10-2018 VAPA_1c14790 59bf7ee1ab5b089b4fba028f7d9fb6cf 185 Pfam PF02620 Uncharacterized ACR, COG1399 67 176 5.7E-20 T 12-10-2018 IPR003772 Large ribosomal RNA subunit accumulation protein YceD VAPA_1c08170 f9945b6c36e68f5c082a5be7ce530211 182 Gene3D G3DSA:2.60.120.10 1 182 2.1E-73 T 12-10-2018 IPR014710 RmlC-like jelly roll fold VAPA_1c08170 f9945b6c36e68f5c082a5be7ce530211 182 TIGRFAM TIGR01221 rmlC: dTDP-4-dehydrorhamnose 3,5-epimerase 3 178 3.1E-80 T 12-10-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 VAPA_1c08170 f9945b6c36e68f5c082a5be7ce530211 182 SUPERFAMILY SSF51182 2 179 5.52E-75 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily VAPA_1c08170 f9945b6c36e68f5c082a5be7ce530211 182 Pfam PF00908 dTDP-4-dehydrorhamnose 3,5-epimerase 6 176 3.9E-73 T 12-10-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 VAPA_1c08170 f9945b6c36e68f5c082a5be7ce530211 182 ProDom PD001462 35-EPIMERASE DTDP-4-DEHYDRORHAMNOSE ISOMERASE RMLC EPIMERASE RELATED DTDP-6-DEOXY-D-GLUCOSE-35-EPIMERASE DTDP-4-KETO-6-DEOXY-D-GLUCOSE DTDP-4-KETO-6-DEOXYGLUCOSE-35-EPIMERASE DTDP-L-RHAMNOSE 4 182 4.0E-80 T 12-10-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 VAPA_1c11420 2560e78aa9f389a8f218c3862c2b5a1d 396 Pfam PF13609 Gram-negative porin 7 363 5.3E-64 T 12-10-2018 VAPA_1c11420 2560e78aa9f389a8f218c3862c2b5a1d 396 SUPERFAMILY SSF56935 20 396 1.26E-65 T 12-10-2018 VAPA_1c11420 2560e78aa9f389a8f218c3862c2b5a1d 396 PRINTS PR00184 Neisseria sp. porin signature 171 188 1.6E-11 T 12-10-2018 IPR002299 Porin, Neisseria sp. type GO:0015288|GO:0016020|GO:0055085 VAPA_1c11420 2560e78aa9f389a8f218c3862c2b5a1d 396 PRINTS PR00184 Neisseria sp. porin signature 71 96 1.6E-11 T 12-10-2018 IPR002299 Porin, Neisseria sp. type GO:0015288|GO:0016020|GO:0055085 VAPA_1c11420 2560e78aa9f389a8f218c3862c2b5a1d 396 PRINTS PR00184 Neisseria sp. porin signature 109 128 1.6E-11 T 12-10-2018 IPR002299 Porin, Neisseria sp. type GO:0015288|GO:0016020|GO:0055085 VAPA_1c11420 2560e78aa9f389a8f218c3862c2b5a1d 396 PRINTS PR00184 Neisseria sp. porin signature 335 359 1.6E-11 T 12-10-2018 IPR002299 Porin, Neisseria sp. type GO:0015288|GO:0016020|GO:0055085 VAPA_1c11420 2560e78aa9f389a8f218c3862c2b5a1d 396 Gene3D G3DSA:2.40.160.10 20 396 8.6E-85 T 12-10-2018 IPR023614 Porin domain superfamily VAPA_1c25400 b6bd6fccbdf71de8140c64a55c35fcfe 216 Gene3D G3DSA:1.10.357.10 66 199 3.3E-18 T 12-10-2018 VAPA_1c25400 b6bd6fccbdf71de8140c64a55c35fcfe 216 SUPERFAMILY SSF48498 95 199 1.51E-12 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily VAPA_1c25400 b6bd6fccbdf71de8140c64a55c35fcfe 216 Gene3D G3DSA:1.10.10.60 18 65 9.7E-15 T 12-10-2018 VAPA_1c25400 b6bd6fccbdf71de8140c64a55c35fcfe 216 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 29 42 3.4E-5 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 VAPA_1c25400 b6bd6fccbdf71de8140c64a55c35fcfe 216 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 50 73 3.4E-5 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 VAPA_1c25400 b6bd6fccbdf71de8140c64a55c35fcfe 216 Pfam PF00440 Bacterial regulatory proteins, tetR family 29 70 8.7E-9 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 VAPA_1c25400 b6bd6fccbdf71de8140c64a55c35fcfe 216 SUPERFAMILY SSF46689 18 87 8.72E-14 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 VAPA_1c48870 7e1018d37afe67bc2b731002a68fa17f 254 Gene3D G3DSA:3.40.1050.10 1 221 1.0E-80 T 12-10-2018 IPR036874 Carbonic anhydrase superfamily GO:0004089|GO:0008270 VAPA_1c48870 7e1018d37afe67bc2b731002a68fa17f 254 SUPERFAMILY SSF53056 3 213 4.58E-71 T 12-10-2018 IPR036874 Carbonic anhydrase superfamily GO:0004089|GO:0008270 VAPA_1c48870 7e1018d37afe67bc2b731002a68fa17f 254 SMART SM00947 31 193 1.0E-63 T 12-10-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 VAPA_1c48870 7e1018d37afe67bc2b731002a68fa17f 254 ProSitePatterns PS00704 Prokaryotic-type carbonic anhydrases signature 1. 43 50 - T 12-10-2018 IPR015892 Carbonic anhydrase, prokaryotic-like, conserved site GO:0004089|GO:0008270|GO:0015976 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 VAPA_1c48870 7e1018d37afe67bc2b731002a68fa17f 254 Pfam PF00484 Carbonic anhydrase 38 188 2.6E-47 T 12-10-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 VAPA_1c42700 dc10bdbdd6fd1f89b341909cd7a587e1 166 Pfam PF04972 BON domain 98 165 8.6E-19 T 12-10-2018 IPR007055 BON domain VAPA_1c42700 dc10bdbdd6fd1f89b341909cd7a587e1 166 SMART SM00749 103 166 6.2E-6 T 12-10-2018 IPR014004 Transport-associated and nodulation domain, bacteria VAPA_1c20190 6f7c8b5834b17e889cc30faaf1a615e9 223 Pfam PF00043 Glutathione S-transferase, C-terminal domain 136 194 3.4E-5 T 12-10-2018 IPR004046 Glutathione S-transferase, C-terminal VAPA_1c20190 6f7c8b5834b17e889cc30faaf1a615e9 223 Gene3D G3DSA:3.40.30.10 1 80 1.8E-21 T 12-10-2018 VAPA_1c20190 6f7c8b5834b17e889cc30faaf1a615e9 223 Pfam PF02798 Glutathione S-transferase, N-terminal domain 3 72 8.2E-11 T 12-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 VAPA_1c20190 6f7c8b5834b17e889cc30faaf1a615e9 223 Gene3D G3DSA:1.20.1050.10 85 205 1.9E-16 T 12-10-2018 VAPA_1c20190 6f7c8b5834b17e889cc30faaf1a615e9 223 SUPERFAMILY SSF47616 90 200 1.03E-20 T 12-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily VAPA_1c20190 6f7c8b5834b17e889cc30faaf1a615e9 223 SUPERFAMILY SSF52833 1 80 1.69E-18 T 12-10-2018 IPR036249 Thioredoxin-like superfamily VAPA_1c16270 0ac19dadd4262d98bc6a7d9417fee640 562 SUPERFAMILY SSF55874 453 562 7.18E-7 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_1c16270 0ac19dadd4262d98bc6a7d9417fee640 562 Pfam PF07730 Histidine kinase 372 434 1.7E-6 T 12-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 VAPA_1c16270 0ac19dadd4262d98bc6a7d9417fee640 562 Gene3D G3DSA:3.30.565.10 445 562 9.4E-14 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_1c02320 e91c50a2f427a4694df1b2800f8a991d 175 SUPERFAMILY SSF160719 47 157 4.45E-10 T 12-10-2018 VAPA_1c02320 e91c50a2f427a4694df1b2800f8a991d 175 Pfam PF04965 Gene 25-like lysozyme 46 149 4.9E-22 T 12-10-2018 IPR007048 GpW/Gp25/anti-adapter protein IraD VAPA_1c02320 e91c50a2f427a4694df1b2800f8a991d 175 TIGRFAM TIGR03357 VI_zyme: type VI secretion system lysozyme-like protein 18 167 5.7E-19 T 12-10-2018 IPR017737 Type VI secretion system, lysozyme-related protein VAPA_2c04790 04db1197cda30602c458914ea54cc9ca 334 Gene3D G3DSA:1.20.1420.30 38 323 1.8E-38 T 12-10-2018 VAPA_2c04790 04db1197cda30602c458914ea54cc9ca 334 Pfam PF01699 Sodium/calcium exchanger protein 184 330 1.3E-13 T 12-10-2018 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 VAPA_2c04790 04db1197cda30602c458914ea54cc9ca 334 Pfam PF01699 Sodium/calcium exchanger protein 9 155 1.4E-11 T 12-10-2018 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 VAPA_2c04790 04db1197cda30602c458914ea54cc9ca 334 Gene3D G3DSA:1.20.58.1130 20 213 1.8E-38 T 12-10-2018 VAPA_1c54350 bb106727818fa2cb3499fb0cee9b3d25 351 Pfam PF01636 Phosphotransferase enzyme family 44 269 8.6E-27 T 12-10-2018 IPR002575 Aminoglycoside phosphotransferase VAPA_1c54350 bb106727818fa2cb3499fb0cee9b3d25 351 SUPERFAMILY SSF56112 17 335 9.19E-58 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily VAPA_1c54350 bb106727818fa2cb3499fb0cee9b3d25 351 Gene3D G3DSA:3.90.1200.10 131 339 3.8E-22 T 12-10-2018 VAPA_2c05850 2510f902afa647bf9c9e9c1e7911f8fd 276 Gene3D G3DSA:3.20.20.60 3 276 2.4E-81 T 12-10-2018 VAPA_2c05850 2510f902afa647bf9c9e9c1e7911f8fd 276 SUPERFAMILY SSF51621 7 230 1.47E-57 T 12-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 VAPA_2c05850 2510f902afa647bf9c9e9c1e7911f8fd 276 PIRSF PIRSF015582 3 276 8.9E-80 T 12-10-2018 IPR011206 Citrate lyase beta subunit-like VAPA_2c05850 2510f902afa647bf9c9e9c1e7911f8fd 276 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 10 218 1.1E-36 T 12-10-2018 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 VAPA_1c21870 71dd34e52ec8830ee2783eacf8636f10 160 Pfam PF01575 MaoC like domain 12 122 1.6E-19 T 12-10-2018 IPR002539 MaoC-like dehydratase domain VAPA_1c21870 71dd34e52ec8830ee2783eacf8636f10 160 Gene3D G3DSA:3.10.129.10 1 160 6.4E-45 T 12-10-2018 VAPA_1c21870 71dd34e52ec8830ee2783eacf8636f10 160 SUPERFAMILY SSF54637 3 150 8.75E-36 T 12-10-2018 IPR029069 HotDog domain superfamily VAPA_1c20080 e9477aa36c179778e8a17a0ce904ab3d 314 Pfam PF01545 Cation efflux family 20 208 1.6E-42 T 12-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 VAPA_1c20080 e9477aa36c179778e8a17a0ce904ab3d 314 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 17 287 1.1E-79 T 12-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 VAPA_1c20080 e9477aa36c179778e8a17a0ce904ab3d 314 Gene3D G3DSA:1.20.1510.10 14 209 2.1E-40 T 12-10-2018 IPR027469 Cation efflux transmembrane domain superfamily VAPA_1c20080 e9477aa36c179778e8a17a0ce904ab3d 314 SUPERFAMILY SSF160240 216 285 1.22E-8 T 12-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 VAPA_1c20080 e9477aa36c179778e8a17a0ce904ab3d 314 SUPERFAMILY SSF161111 17 210 5.75E-53 T 12-10-2018 IPR027469 Cation efflux transmembrane domain superfamily VAPA_1c00380 a492bbb89835412a72b77a6b554a2bda 367 Gene3D G3DSA:3.20.20.70 1 367 7.2E-151 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 VAPA_1c00380 a492bbb89835412a72b77a6b554a2bda 367 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 3 345 2.3E-84 T 12-10-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 VAPA_1c00380 a492bbb89835412a72b77a6b554a2bda 367 SUPERFAMILY SSF51395 1 366 1.56E-120 T 12-10-2018 VAPA_1c08480 3a5ab3ec3351f8e72e220ea5bfe95825 237 Pfam PF00392 Bacterial regulatory proteins, gntR family 11 74 7.9E-24 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_1c08480 3a5ab3ec3351f8e72e220ea5bfe95825 237 SMART SM00895 94 220 7.1E-18 T 12-10-2018 IPR011711 GntR, C-terminal VAPA_1c08480 3a5ab3ec3351f8e72e220ea5bfe95825 237 Pfam PF07729 FCD domain 94 219 9.1E-22 T 12-10-2018 IPR011711 GntR, C-terminal VAPA_1c08480 3a5ab3ec3351f8e72e220ea5bfe95825 237 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 48 64 2.1E-10 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_1c08480 3a5ab3ec3351f8e72e220ea5bfe95825 237 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 34 48 2.1E-10 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_1c08480 3a5ab3ec3351f8e72e220ea5bfe95825 237 Gene3D G3DSA:1.20.120.530 88 229 2.7E-27 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal VAPA_1c08480 3a5ab3ec3351f8e72e220ea5bfe95825 237 SUPERFAMILY SSF46785 5 101 2.46E-25 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c08480 3a5ab3ec3351f8e72e220ea5bfe95825 237 SMART SM00345 15 74 6.7E-26 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_1c08480 3a5ab3ec3351f8e72e220ea5bfe95825 237 Gene3D G3DSA:1.10.10.10 5 81 6.9E-25 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c08480 3a5ab3ec3351f8e72e220ea5bfe95825 237 SUPERFAMILY SSF48008 93 226 2.38E-26 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal VAPA_1c20580 3cc92168d38b6902649a8eb47f971198 242 SUPERFAMILY SSF49354 20 139 7.06E-20 T 12-10-2018 IPR008962 PapD-like superfamily VAPA_1c20580 3cc92168d38b6902649a8eb47f971198 242 Pfam PF00345 Pili and flagellar-assembly chaperone, PapD N-terminal domain 24 143 1.3E-19 T 12-10-2018 IPR016147 Pili assembly chaperone, N-terminal GO:0030288|GO:0071555 VAPA_1c20580 3cc92168d38b6902649a8eb47f971198 242 Gene3D G3DSA:2.60.40.10 31 143 7.5E-6 T 12-10-2018 IPR013783 Immunoglobulin-like fold VAPA_2c04320 dd1a25694e2b59657dd5738758bf98a9 374 Gene3D G3DSA:3.90.180.10 43 359 3.5E-101 T 12-10-2018 VAPA_2c04320 dd1a25694e2b59657dd5738758bf98a9 374 SUPERFAMILY SSF51735 170 320 1.69E-38 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_2c04320 dd1a25694e2b59657dd5738758bf98a9 374 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 88 102 - T 12-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 VAPA_2c04320 dd1a25694e2b59657dd5738758bf98a9 374 SMART SM00829 39 372 3.3E-4 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 VAPA_2c04320 dd1a25694e2b59657dd5738758bf98a9 374 Gene3D G3DSA:3.40.50.720 183 318 3.5E-101 T 12-10-2018 VAPA_2c04320 dd1a25694e2b59657dd5738758bf98a9 374 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 54 159 5.5E-30 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 VAPA_2c04320 dd1a25694e2b59657dd5738758bf98a9 374 Pfam PF00107 Zinc-binding dehydrogenase 206 319 2.3E-23 T 12-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 VAPA_2c04320 dd1a25694e2b59657dd5738758bf98a9 374 SUPERFAMILY SSF50129 30 184 4.72E-56 T 12-10-2018 IPR011032 GroES-like superfamily VAPA_1c32180 6f33fc546641d47010c965a97edafef6 273 ProSitePatterns PS00211 ABC transporters family signature. 144 158 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_1c32180 6f33fc546641d47010c965a97edafef6 273 Pfam PF00005 ABC transporter 18 172 9.0E-32 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c32180 6f33fc546641d47010c965a97edafef6 273 SUPERFAMILY SSF52540 2 231 1.15E-58 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c32180 6f33fc546641d47010c965a97edafef6 273 SMART SM00382 27 221 6.3E-8 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c32180 6f33fc546641d47010c965a97edafef6 273 TIGRFAM TIGR02315 ABC_phnC: phosphonate ABC transporter, ATP-binding protein 1 241 4.4E-82 T 12-10-2018 IPR012693 ABC transporter, phosphonate import, PhnC GO:0005524|GO:0015416|GO:0015716|GO:0016020 VAPA_1c32180 6f33fc546641d47010c965a97edafef6 273 Gene3D G3DSA:3.40.50.300 1 240 2.0E-63 T 12-10-2018 VAPA_1c31480 27b206cd54c4426d2d6a2378fe867d24 305 SUPERFAMILY SSF53223 4 98 2.07E-35 T 12-10-2018 VAPA_1c31480 27b206cd54c4426d2d6a2378fe867d24 305 Gene3D G3DSA:3.40.50.720 107 264 7.4E-100 T 12-10-2018 VAPA_1c31480 27b206cd54c4426d2d6a2378fe867d24 305 Gene3D G3DSA:3.40.50.10280 6 293 7.4E-100 T 12-10-2018 IPR037089 Methylene-tetrahydromethanopterin dehydrogenase, N-terminal domain superfamily VAPA_1c31480 27b206cd54c4426d2d6a2378fe867d24 305 Pfam PF09176 Methylene-tetrahydromethanopterin dehydrogenase, N-terminal 18 98 5.0E-35 T 12-10-2018 IPR015259 Methylene-tetrahydromethanopterin dehydrogenase, N-terminal VAPA_1c31480 27b206cd54c4426d2d6a2378fe867d24 305 SUPERFAMILY SSF51735 114 213 2.24E-14 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c54340 1e5f9ea8375193293c14e93059b77a28 427 SUPERFAMILY SSF53383 22 424 4.23E-104 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase VAPA_1c54340 1e5f9ea8375193293c14e93059b77a28 427 PIRSF PIRSF000521 27 156 7.6E-6 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 VAPA_1c54340 1e5f9ea8375193293c14e93059b77a28 427 PIRSF PIRSF000521 183 427 2.5E-33 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 VAPA_1c54340 1e5f9ea8375193293c14e93059b77a28 427 Pfam PF00202 Aminotransferase class-III 31 424 4.4E-72 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 VAPA_1c54340 1e5f9ea8375193293c14e93059b77a28 427 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 237 275 - T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 VAPA_1c54340 1e5f9ea8375193293c14e93059b77a28 427 Gene3D G3DSA:3.90.1150.10 30 420 4.2E-138 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 VAPA_1c54340 1e5f9ea8375193293c14e93059b77a28 427 Gene3D G3DSA:3.40.640.10 63 322 4.2E-138 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 VAPA_1c34890 3374cdeb08c6acc3331c80d8a5c4b0d4 296 SUPERFAMILY SSF161098 54 278 6.93E-47 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c34890 3374cdeb08c6acc3331c80d8a5c4b0d4 296 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 84 285 3.8E-18 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 VAPA_1c34890 3374cdeb08c6acc3331c80d8a5c4b0d4 296 Gene3D G3DSA:1.10.3720.10 49 292 4.4E-52 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_2c09730 00a44688a3bc0799d1504560c89eb1b3 322 SUPERFAMILY SSF63380 15 108 3.97E-23 T 12-10-2018 IPR017938 Riboflavin synthase-like beta-barrel VAPA_2c09730 00a44688a3bc0799d1504560c89eb1b3 322 SUPERFAMILY SSF52343 106 230 7.33E-29 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain VAPA_2c09730 00a44688a3bc0799d1504560c89eb1b3 322 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 243 313 2.8E-12 T 12-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 VAPA_2c09730 00a44688a3bc0799d1504560c89eb1b3 322 Gene3D G3DSA:2.40.30.10 10 109 1.8E-25 T 12-10-2018 VAPA_2c09730 00a44688a3bc0799d1504560c89eb1b3 322 Gene3D G3DSA:3.40.50.80 110 225 4.3E-27 T 12-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain VAPA_2c09730 00a44688a3bc0799d1504560c89eb1b3 322 SUPERFAMILY SSF54292 216 322 1.44E-27 T 12-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 VAPA_2c09730 00a44688a3bc0799d1504560c89eb1b3 322 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 271 279 - T 12-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 VAPA_2c09730 00a44688a3bc0799d1504560c89eb1b3 322 PRINTS PR00409 Phthalate dioxygenase reductase family signature 84 98 3.3E-35 T 12-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 VAPA_2c09730 00a44688a3bc0799d1504560c89eb1b3 322 PRINTS PR00409 Phthalate dioxygenase reductase family signature 145 154 3.3E-35 T 12-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 VAPA_2c09730 00a44688a3bc0799d1504560c89eb1b3 322 PRINTS PR00409 Phthalate dioxygenase reductase family signature 195 203 3.3E-35 T 12-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 VAPA_2c09730 00a44688a3bc0799d1504560c89eb1b3 322 PRINTS PR00409 Phthalate dioxygenase reductase family signature 40 50 3.3E-35 T 12-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 VAPA_2c09730 00a44688a3bc0799d1504560c89eb1b3 322 PRINTS PR00409 Phthalate dioxygenase reductase family signature 120 139 3.3E-35 T 12-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 VAPA_2c09730 00a44688a3bc0799d1504560c89eb1b3 322 PRINTS PR00409 Phthalate dioxygenase reductase family signature 98 112 3.3E-35 T 12-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 VAPA_2c09730 00a44688a3bc0799d1504560c89eb1b3 322 PRINTS PR00409 Phthalate dioxygenase reductase family signature 50 62 3.3E-35 T 12-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 VAPA_2c09730 00a44688a3bc0799d1504560c89eb1b3 322 Gene3D G3DSA:3.10.20.30 231 322 2.8E-24 T 12-10-2018 IPR012675 Beta-grasp domain superfamily VAPA_1c51150 ea75fc8b5ce8b812fdbb33c1948b48be 213 TIGRFAM TIGR00427 TIGR00427: membrane protein, MarC family 4 202 3.1E-49 T 12-10-2018 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 VAPA_1c51150 ea75fc8b5ce8b812fdbb33c1948b48be 213 Pfam PF01914 MarC family integral membrane protein 3 205 8.8E-50 T 12-10-2018 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 VAPA_1c26880 99d92c22236d3542e5f9d0da5af8c900 885 Gene3D G3DSA:2.160.20.80 544 737 2.0E-30 T 12-10-2018 VAPA_1c26880 99d92c22236d3542e5f9d0da5af8c900 885 Gene3D G3DSA:2.160.20.80 738 877 2.0E-22 T 12-10-2018 VAPA_1c26880 99d92c22236d3542e5f9d0da5af8c900 885 Pfam PF00805 Pentapeptide repeats (8 copies) 565 591 1.3E-4 T 12-10-2018 IPR001646 Pentapeptide repeat VAPA_1c26880 99d92c22236d3542e5f9d0da5af8c900 885 Pfam PF00805 Pentapeptide repeats (8 copies) 797 834 9.0E-8 T 12-10-2018 IPR001646 Pentapeptide repeat VAPA_1c26880 99d92c22236d3542e5f9d0da5af8c900 885 Pfam PF09937 Uncharacterized protein conserved in bacteria (DUF2169) 20 303 3.5E-79 T 12-10-2018 IPR018683 Domain of unknown function DUF2169 VAPA_1c26880 99d92c22236d3542e5f9d0da5af8c900 885 SUPERFAMILY SSF141571 564 855 6.04E-28 T 12-10-2018 VAPA_1c26880 99d92c22236d3542e5f9d0da5af8c900 885 SUPERFAMILY SSF141571 639 756 2.0E-13 T 12-10-2018 VAPA_1c26880 99d92c22236d3542e5f9d0da5af8c900 885 Pfam PF13599 Pentapeptide repeats (9 copies) 695 784 1.3E-6 T 12-10-2018 IPR001646 Pentapeptide repeat VAPA_1c26880 99d92c22236d3542e5f9d0da5af8c900 885 Pfam PF13599 Pentapeptide repeats (9 copies) 619 687 2.9E-7 T 12-10-2018 IPR001646 Pentapeptide repeat VAPA_1c40660 9c465604b6570be94766a0d783d9a7e0 307 Pfam PF03466 LysR substrate binding domain 89 284 2.8E-33 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_1c40660 9c465604b6570be94766a0d783d9a7e0 307 Gene3D G3DSA:3.40.190.10 95 271 8.0E-24 T 12-10-2018 VAPA_1c40660 9c465604b6570be94766a0d783d9a7e0 307 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 2.4E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c40660 9c465604b6570be94766a0d783d9a7e0 307 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 2.4E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c40660 9c465604b6570be94766a0d783d9a7e0 307 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 2.4E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c40660 9c465604b6570be94766a0d783d9a7e0 307 SUPERFAMILY SSF53850 90 291 1.06E-33 T 12-10-2018 VAPA_1c40660 9c465604b6570be94766a0d783d9a7e0 307 SUPERFAMILY SSF46785 2 110 6.08E-22 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c40660 9c465604b6570be94766a0d783d9a7e0 307 Gene3D G3DSA:3.40.190.10 163 265 8.0E-24 T 12-10-2018 VAPA_1c40660 9c465604b6570be94766a0d783d9a7e0 307 Gene3D G3DSA:1.10.10.10 1 93 1.4E-20 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c40660 9c465604b6570be94766a0d783d9a7e0 307 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 63 5.4E-18 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c28030 1b65013a54a96927096d52effefbf2b3 171 Gene3D G3DSA:1.10.10.10 99 158 7.9E-22 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c28030 1b65013a54a96927096d52effefbf2b3 171 SUPERFAMILY SSF88659 100 157 2.99E-18 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like VAPA_1c28030 1b65013a54a96927096d52effefbf2b3 171 SUPERFAMILY SSF88946 4 68 2.2E-14 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 VAPA_1c28030 1b65013a54a96927096d52effefbf2b3 171 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 10 155 5.5E-21 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 VAPA_1c28030 1b65013a54a96927096d52effefbf2b3 171 Gene3D G3DSA:1.10.1740.10 3 64 1.6E-23 T 12-10-2018 VAPA_1c28030 1b65013a54a96927096d52effefbf2b3 171 Pfam PF08281 Sigma-70, region 4 101 152 2.9E-19 T 12-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 VAPA_1c28030 1b65013a54a96927096d52effefbf2b3 171 Pfam PF04542 Sigma-70 region 2 10 69 2.6E-11 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 VAPA_1c15490 49b892fa239e642c53c45efaa9be54fa 283 Gene3D G3DSA:1.25.40.10 198 280 1.1E-6 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 VAPA_1c15490 49b892fa239e642c53c45efaa9be54fa 283 Pfam PF13369 Transglutaminase-like superfamily 44 202 1.9E-51 T 12-10-2018 IPR032698 Protein SirB1, N-terminal Reactome: R-HSA-8951664|Reactome: R-HSA-983168 VAPA_1c15490 49b892fa239e642c53c45efaa9be54fa 283 SUPERFAMILY SSF48452 177 280 6.65E-9 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 VAPA_1c15490 49b892fa239e642c53c45efaa9be54fa 283 Pfam PF13371 Tetratricopeptide repeat 204 275 2.0E-22 T 12-10-2018 VAPA_1c53970 8349a9c60c73435b31c12d47d163cacd 266 Gene3D G3DSA:3.60.40.10 8 260 2.0E-65 T 12-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 VAPA_1c53970 8349a9c60c73435b31c12d47d163cacd 266 SMART SM00331 23 259 8.4E-33 T 12-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 VAPA_1c53970 8349a9c60c73435b31c12d47d163cacd 266 Pfam PF13672 Protein phosphatase 2C 28 223 1.9E-19 T 12-10-2018 VAPA_1c53970 8349a9c60c73435b31c12d47d163cacd 266 SMART SM00332 8 257 4.6E-16 T 12-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 VAPA_1c53970 8349a9c60c73435b31c12d47d163cacd 266 SUPERFAMILY SSF81606 17 258 6.67E-60 T 12-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 VAPA_1c03280 79d393f6509fa7256f7c4067faf66902 117 SUPERFAMILY SSF54427 2 115 5.17E-35 T 12-10-2018 IPR032710 NTF2-like domain superfamily VAPA_1c03280 79d393f6509fa7256f7c4067faf66902 117 Gene3D G3DSA:3.10.450.50 1 116 3.8E-43 T 12-10-2018 VAPA_1c03280 79d393f6509fa7256f7c4067faf66902 117 Pfam PF11533 Protein of unknown function (DUF3225) 1 115 3.3E-50 T 12-10-2018 IPR024507 Protein of unknown function DUF3225 VAPA_1c26960 5ee0a6f01dc4191c4c747b4b270dec8b 340 Gene3D G3DSA:3.30.160.60 300 333 1.1E-8 T 12-10-2018 VAPA_1c26960 5ee0a6f01dc4191c4c747b4b270dec8b 340 Pfam PF02618 YceG-like family 41 325 1.6E-76 T 12-10-2018 IPR003770 Endolytic murein transglycosylase VAPA_1c26960 5ee0a6f01dc4191c4c747b4b270dec8b 340 Hamap MF_02065 Endolytic murein transglycosylase [mltG]. 6 329 32.377 T 12-10-2018 IPR003770 Endolytic murein transglycosylase VAPA_1c26960 5ee0a6f01dc4191c4c747b4b270dec8b 340 TIGRFAM TIGR00247 TIGR00247: conserved hypothetical protein, YceG family 36 328 1.1E-77 T 12-10-2018 IPR003770 Endolytic murein transglycosylase VAPA_1c42650 231f7a77d8c5b4b185374e21c3f618e4 54 PIRSF PIRSF036466 1 54 3.9E-19 T 12-10-2018 IPR009760 Protein of unknown function DUF1328 GO:0005886 VAPA_1c42650 231f7a77d8c5b4b185374e21c3f618e4 54 Pfam PF07043 Protein of unknown function (DUF1328) 6 43 1.0E-13 T 12-10-2018 IPR009760 Protein of unknown function DUF1328 GO:0005886 VAPA_1c42650 231f7a77d8c5b4b185374e21c3f618e4 54 Hamap MF_01361 UPF0391 membrane protein YtjA [ytjA]. 1 50 19.113 T 12-10-2018 IPR009760 Protein of unknown function DUF1328 GO:0005886 VAPA_1c06290 2e9464f4a85552a249075643b8b7ac0b 372 Pfam PF14331 ImcF-related N-terminal domain 151 338 3.8E-37 T 12-10-2018 IPR025743 ImcF-related, N-terminal domain VAPA_1c46000 a1c88eba4020bf9e133878b16f796071 602 SUPERFAMILY SSF52833 292 424 7.05E-34 T 12-10-2018 IPR036249 Thioredoxin-like superfamily VAPA_1c46000 a1c88eba4020bf9e133878b16f796071 602 Gene3D G3DSA:2.60.120.260 452 601 1.8E-23 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily VAPA_1c46000 a1c88eba4020bf9e133878b16f796071 602 Pfam PF00578 AhpC/TSA family 305 405 1.3E-11 T 12-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 VAPA_1c46000 a1c88eba4020bf9e133878b16f796071 602 Gene3D G3DSA:3.40.30.10 267 433 3.6E-45 T 12-10-2018 VAPA_1c46000 a1c88eba4020bf9e133878b16f796071 602 Pfam PF02683 Cytochrome C biogenesis protein transmembrane region 7 212 1.6E-13 T 12-10-2018 IPR003834 Cytochrome C biogenesis protein, transmembrane domain GO:0016020|GO:0017004|GO:0055114 VAPA_1c52060 eb50c46f179e32491bba319109e4b3c1 324 Gene3D G3DSA:3.40.190.10 121 246 5.3E-98 T 12-10-2018 VAPA_1c52060 eb50c46f179e32491bba319109e4b3c1 324 Gene3D G3DSA:3.40.190.150 26 317 5.3E-98 T 12-10-2018 VAPA_1c52060 eb50c46f179e32491bba319109e4b3c1 324 PIRSF PIRSF017082 1 324 1.7E-67 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c52060 eb50c46f179e32491bba319109e4b3c1 324 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 43 320 8.1E-75 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c52060 eb50c46f179e32491bba319109e4b3c1 324 SUPERFAMILY SSF53850 107 279 3.43E-10 T 12-10-2018 VAPA_2c13000 1531e18e4002664e877f927518f565eb 173 Pfam PF01381 Helix-turn-helix 9 48 3.6E-11 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 VAPA_2c13000 1531e18e4002664e877f927518f565eb 173 Pfam PF07883 Cupin domain 99 167 2.4E-12 T 12-10-2018 IPR013096 Cupin 2, conserved barrel VAPA_2c13000 1531e18e4002664e877f927518f565eb 173 Gene3D G3DSA:1.10.260.40 2 59 9.0E-13 T 12-10-2018 VAPA_2c13000 1531e18e4002664e877f927518f565eb 173 SUPERFAMILY SSF51182 43 169 2.09E-22 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily VAPA_2c13000 1531e18e4002664e877f927518f565eb 173 Gene3D G3DSA:2.60.120.10 65 169 2.4E-16 T 12-10-2018 IPR014710 RmlC-like jelly roll fold VAPA_2c13000 1531e18e4002664e877f927518f565eb 173 SMART SM00530 1 50 8.3E-6 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 VAPA_2c13000 1531e18e4002664e877f927518f565eb 173 SUPERFAMILY SSF47413 4 54 2.2E-12 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 VAPA_1c02780 89ca1e1fae0d426bba51a493b26915ca 311 Pfam PF08450 SMP-30/Gluconolaconase/LRE-like region 12 276 8.2E-67 T 12-10-2018 IPR013658 SMP-30/Gluconolactonase/LRE-like region VAPA_1c02780 89ca1e1fae0d426bba51a493b26915ca 311 Gene3D G3DSA:2.120.10.30 2 310 1.3E-86 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like VAPA_1c02780 89ca1e1fae0d426bba51a493b26915ca 311 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 140 162 2.8E-28 T 12-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) VAPA_1c02780 89ca1e1fae0d426bba51a493b26915ca 311 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 93 114 2.8E-28 T 12-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) VAPA_1c02780 89ca1e1fae0d426bba51a493b26915ca 311 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 13 30 2.8E-28 T 12-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) VAPA_1c02780 89ca1e1fae0d426bba51a493b26915ca 311 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 163 183 2.8E-28 T 12-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) VAPA_1c02780 89ca1e1fae0d426bba51a493b26915ca 311 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 258 276 2.8E-28 T 12-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) VAPA_1c02780 89ca1e1fae0d426bba51a493b26915ca 311 SUPERFAMILY SSF63829 10 308 2.18E-55 T 12-10-2018 VAPA_1c16790 97941a67a11b60588bd8d3825b0ef3d9 256 SMART SM00382 31 226 4.1E-5 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c16790 97941a67a11b60588bd8d3825b0ef3d9 256 Gene3D G3DSA:3.40.50.300 6 253 4.3E-57 T 12-10-2018 VAPA_1c16790 97941a67a11b60588bd8d3825b0ef3d9 256 SUPERFAMILY SSF52540 6 248 3.88E-57 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c16790 97941a67a11b60588bd8d3825b0ef3d9 256 ProSitePatterns PS00211 ABC transporters family signature. 151 165 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_1c16790 97941a67a11b60588bd8d3825b0ef3d9 256 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 226 248 4.7E-8 T 12-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal VAPA_1c16790 97941a67a11b60588bd8d3825b0ef3d9 256 Pfam PF00005 ABC transporter 24 179 9.4E-29 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c35580 c55a6b1d00fba32a92a94d23870c2626 332 Gene3D G3DSA:3.55.30.10 2 189 2.5E-53 T 12-10-2018 IPR016153 Heat shock protein Hsp33, N-terminal GO:0005737|GO:0006457|GO:0051082 VAPA_1c35580 c55a6b1d00fba32a92a94d23870c2626 332 Gene3D G3DSA:3.90.1280.10 263 320 2.1E-20 T 12-10-2018 IPR016154 Heat shock protein Hsp33, C-terminal GO:0005737|GO:0006457|GO:0051082 VAPA_1c35580 c55a6b1d00fba32a92a94d23870c2626 332 SUPERFAMILY SSF118352 264 319 1.44E-17 T 12-10-2018 IPR016154 Heat shock protein Hsp33, C-terminal GO:0005737|GO:0006457|GO:0051082 VAPA_1c35580 c55a6b1d00fba32a92a94d23870c2626 332 Gene3D G3DSA:1.10.287.480 211 258 3.9E-11 T 12-10-2018 IPR023212 Heat shock protein Hsp33, helix hairpin bin domain superfamily VAPA_1c35580 c55a6b1d00fba32a92a94d23870c2626 332 Pfam PF01430 Hsp33 protein 3 310 7.9E-74 T 12-10-2018 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 VAPA_1c35580 c55a6b1d00fba32a92a94d23870c2626 332 SUPERFAMILY SSF64397 4 271 4.19E-49 T 12-10-2018 IPR016153 Heat shock protein Hsp33, N-terminal GO:0005737|GO:0006457|GO:0051082 VAPA_1c35580 c55a6b1d00fba32a92a94d23870c2626 332 PIRSF PIRSF005261 1 320 4.1E-54 T 12-10-2018 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 VAPA_1c53480 387a8af768a814e59c7b67ce08979dd8 271 SUPERFAMILY SSF56317 1 268 6.67E-81 T 12-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily VAPA_1c53480 387a8af768a814e59c7b67ce08979dd8 271 Pfam PF00795 Carbon-nitrogen hydrolase 2 260 8.3E-53 T 12-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 VAPA_1c53480 387a8af768a814e59c7b67ce08979dd8 271 ProSitePatterns PS01227 Uncharacterized protein family UPF0012 signature. 154 174 - T 12-10-2018 IPR001110 Uncharacterised protein family UPF0012, conserved site VAPA_1c53480 387a8af768a814e59c7b67ce08979dd8 271 Gene3D G3DSA:3.60.110.10 1 270 2.4E-86 T 12-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily VAPA_1c36830 fbc92a1b7c20f2b2f00c8507fd331a58 243 PIRSF PIRSF004808 1 242 1.1E-60 T 12-10-2018 IPR004384 RNA methyltransferase TrmJ/LasT GO:0006396|GO:0008173 VAPA_1c36830 fbc92a1b7c20f2b2f00c8507fd331a58 243 SUPERFAMILY SSF75217 3 161 3.01E-30 T 12-10-2018 IPR029028 Alpha/beta knot methyltransferases VAPA_1c36830 fbc92a1b7c20f2b2f00c8507fd331a58 243 TIGRFAM TIGR00050 rRNA_methyl_1: RNA methyltransferase, TrmH family, group 1 2 233 9.8E-52 T 12-10-2018 IPR004384 RNA methyltransferase TrmJ/LasT GO:0006396|GO:0008173 VAPA_1c36830 fbc92a1b7c20f2b2f00c8507fd331a58 243 Gene3D G3DSA:3.40.1280.10 1 164 4.2E-55 T 12-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal VAPA_1c36830 fbc92a1b7c20f2b2f00c8507fd331a58 243 Gene3D G3DSA:1.10.8.590 173 234 2.1E-20 T 12-10-2018 VAPA_1c36830 fbc92a1b7c20f2b2f00c8507fd331a58 243 Pfam PF00588 SpoU rRNA Methylase family 4 154 1.2E-27 T 12-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 VAPA_1c39600 a80ebbadcf8e1a6a2525883420f1e555 506 Gene3D G3DSA:3.40.640.10 130 488 1.5E-88 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 VAPA_1c39600 a80ebbadcf8e1a6a2525883420f1e555 506 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 60 76 1.4E-6 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_1c39600 a80ebbadcf8e1a6a2525883420f1e555 506 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 46 60 1.4E-6 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_1c39600 a80ebbadcf8e1a6a2525883420f1e555 506 Pfam PF00155 Aminotransferase class I and II 198 461 1.0E-12 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 VAPA_1c39600 a80ebbadcf8e1a6a2525883420f1e555 506 SUPERFAMILY SSF53383 135 494 8.7E-74 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase VAPA_1c39600 a80ebbadcf8e1a6a2525883420f1e555 506 SUPERFAMILY SSF46785 19 93 4.21E-17 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c39600 a80ebbadcf8e1a6a2525883420f1e555 506 Pfam PF00392 Bacterial regulatory proteins, gntR family 24 86 1.8E-14 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_1c39600 a80ebbadcf8e1a6a2525883420f1e555 506 SMART SM00345 27 86 3.1E-13 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_1c39600 a80ebbadcf8e1a6a2525883420f1e555 506 Gene3D G3DSA:1.10.10.10 20 110 5.9E-18 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c52530 3b989a4ec50c763e32a93a0354948811 380 SUPERFAMILY SSF50969 163 369 5.49E-6 T 12-10-2018 IPR011044 Quinoprotein amine dehydrogenase, beta chain-like VAPA_1c52530 3b989a4ec50c763e32a93a0354948811 380 Pfam PF13449 Esterase-like activity of phytase 55 363 7.4E-77 T 12-10-2018 IPR027372 Phytase-like domain VAPA_1c36570 25cc7230643251414c49357a99a268df 91 Pfam PF14026 Protein of unknown function (DUF4242) 4 76 3.9E-18 T 12-10-2018 IPR025336 Protein of unknown function DUF4242 VAPA_1c36570 25cc7230643251414c49357a99a268df 91 Gene3D G3DSA:3.30.70.3090 12 79 4.2E-5 T 12-10-2018 VAPA_2c11780 73f555093e80a0375da6dec4300d2bb2 169 Gene3D G3DSA:1.20.120.450 1 167 5.4E-56 T 12-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes VAPA_2c11780 73f555093e80a0375da6dec4300d2bb2 169 Pfam PF09351 Domain of unknown function (DUF1993) 5 166 8.4E-60 T 12-10-2018 IPR018531 Protein of unknown function DUF1993 VAPA_2c11780 73f555093e80a0375da6dec4300d2bb2 169 SUPERFAMILY SSF109854 5 168 4.21E-60 T 12-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes VAPA_1c49800 df7d449630065c2186fbfbadafb3ca95 347 Pfam PF00437 Type II/IV secretion system protein 12 267 1.4E-45 T 12-10-2018 IPR001482 Type II/IV secretion system protein VAPA_1c49800 df7d449630065c2186fbfbadafb3ca95 347 Gene3D G3DSA:3.40.50.300 101 346 1.2E-101 T 12-10-2018 VAPA_1c49800 df7d449630065c2186fbfbadafb3ca95 347 TIGRFAM TIGR01420 pilT_fam: twitching motility protein 3 343 1.1E-152 T 12-10-2018 IPR006321 Pilus retraction protein PilT GO:0005524 VAPA_1c49800 df7d449630065c2186fbfbadafb3ca95 347 Gene3D G3DSA:3.30.450.90 1 100 8.3E-34 T 12-10-2018 VAPA_1c49800 df7d449630065c2186fbfbadafb3ca95 347 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 193 207 - T 12-10-2018 IPR001482 Type II/IV secretion system protein VAPA_1c49800 df7d449630065c2186fbfbadafb3ca95 347 SUPERFAMILY SSF52540 5 335 4.57E-76 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_2c03020 390d7cc7759be6d58e0654296acec47b 224 ProDom PD037589 AROM ARO OPERON REGULATED BY AROR BIOSYNTHESIS TRANSCRIPTION AMINO AROMATIC 61 109 0.008 T 12-10-2018 IPR010843 Uncharacterised protein family AroM VAPA_1c26150 0ce2919bd0e51983688f4ef7b4c18991 93 SUPERFAMILY SSF82657 9 91 1.11E-22 T 12-10-2018 IPR036065 BolA-like superfamily VAPA_1c26150 0ce2919bd0e51983688f4ef7b4c18991 93 PIRSF PIRSF003113 1 93 1.2E-25 T 12-10-2018 IPR002634 BolA protein VAPA_1c26150 0ce2919bd0e51983688f4ef7b4c18991 93 Pfam PF01722 BolA-like protein 19 92 5.1E-27 T 12-10-2018 IPR002634 BolA protein VAPA_1c26150 0ce2919bd0e51983688f4ef7b4c18991 93 Gene3D G3DSA:3.30.300.90 9 93 1.8E-26 T 12-10-2018 VAPA_1c00890 6a8843b42fe3e240b6f7c2982611073f 390 Pfam PF13458 Periplasmic binding protein 30 368 1.0E-69 T 12-10-2018 IPR028081 Leucine-binding protein domain VAPA_1c00890 6a8843b42fe3e240b6f7c2982611073f 390 Gene3D G3DSA:3.40.50.2300 147 365 7.4E-111 T 12-10-2018 VAPA_1c00890 6a8843b42fe3e240b6f7c2982611073f 390 SUPERFAMILY SSF53822 30 383 2.36E-84 T 12-10-2018 IPR028082 Periplasmic binding protein-like I VAPA_1c00890 6a8843b42fe3e240b6f7c2982611073f 390 Gene3D G3DSA:3.40.50.2300 31 359 7.4E-111 T 12-10-2018 VAPA_1c13460 9365fd073e9a3ee1a38d3c6ece21fc93 423 Pfam PF01189 16S rRNA methyltransferase RsmB/F 213 418 1.6E-47 T 12-10-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 VAPA_1c13460 9365fd073e9a3ee1a38d3c6ece21fc93 423 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 293 305 3.1E-29 T 12-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase VAPA_1c13460 9365fd073e9a3ee1a38d3c6ece21fc93 423 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 224 234 3.1E-29 T 12-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase VAPA_1c13460 9365fd073e9a3ee1a38d3c6ece21fc93 423 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 405 422 3.1E-29 T 12-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase VAPA_1c13460 9365fd073e9a3ee1a38d3c6ece21fc93 423 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 343 359 3.1E-29 T 12-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase VAPA_1c13460 9365fd073e9a3ee1a38d3c6ece21fc93 423 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 195 209 3.1E-29 T 12-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase VAPA_1c13460 9365fd073e9a3ee1a38d3c6ece21fc93 423 Gene3D G3DSA:3.40.50.150 112 422 1.6E-81 T 12-10-2018 VAPA_1c13460 9365fd073e9a3ee1a38d3c6ece21fc93 423 SUPERFAMILY SSF53335 114 422 6.5E-68 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase VAPA_1c25860 f3b9086d87a2d9f4c090d01aa50c858e 185 Pfam PF03358 NADPH-dependent FMN reductase 4 144 7.9E-38 T 12-10-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 VAPA_1c25860 f3b9086d87a2d9f4c090d01aa50c858e 185 SUPERFAMILY SSF52218 5 175 8.02E-48 T 12-10-2018 IPR029039 Flavoprotein-like superfamily VAPA_1c25860 f3b9086d87a2d9f4c090d01aa50c858e 185 Gene3D G3DSA:3.40.50.360 4 184 1.5E-52 T 12-10-2018 IPR029039 Flavoprotein-like superfamily VAPA_1c10130 c5f26c01346417714652e02fbd9bcaf3 269 Pfam PF01578 Cytochrome C assembly protein 61 262 4.6E-24 T 12-10-2018 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 VAPA_1c13390 db57e51e227eced8c931f7d3db34abfc 453 SUPERFAMILY SSF53474 33 160 1.54E-20 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c13390 db57e51e227eced8c931f7d3db34abfc 453 Pfam PF01674 Lipase (class 2) 36 147 7.1E-6 T 12-10-2018 IPR002918 Lipase EstA/Esterase EstB GO:0016787 KEGG: 00561+3.1.1.3|MetaCyc: PWY-6857 VAPA_2c05710 146e446012e7d27a782dcd0fc3dbcb7d 329 PIRSF PIRSF017082 2 328 4.9E-70 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_2c05710 146e446012e7d27a782dcd0fc3dbcb7d 329 SUPERFAMILY SSF53850 116 288 1.26E-11 T 12-10-2018 VAPA_2c05710 146e446012e7d27a782dcd0fc3dbcb7d 329 Gene3D G3DSA:3.40.190.10 131 253 1.5E-101 T 12-10-2018 VAPA_2c05710 146e446012e7d27a782dcd0fc3dbcb7d 329 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 53 322 3.1E-76 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_2c05710 146e446012e7d27a782dcd0fc3dbcb7d 329 Gene3D G3DSA:3.40.190.150 33 319 1.5E-101 T 12-10-2018 VAPA_1c44320 f8b34e3b98fb8469e510ffb1de005cbc 393 Gene3D G3DSA:3.30.1540.10 236 327 3.8E-134 T 12-10-2018 VAPA_1c44320 f8b34e3b98fb8469e510ffb1de005cbc 393 Pfam PF02515 CoA-transferase family III 9 376 1.8E-131 T 12-10-2018 IPR003673 CoA-transferase family III GO:0003824 VAPA_1c44320 f8b34e3b98fb8469e510ffb1de005cbc 393 SUPERFAMILY SSF89796 7 387 1.83E-136 T 12-10-2018 IPR023606 CoA-transferase family III domain superfamily VAPA_1c44320 f8b34e3b98fb8469e510ffb1de005cbc 393 Gene3D G3DSA:3.40.50.10540 8 385 3.8E-134 T 12-10-2018 IPR023606 CoA-transferase family III domain superfamily VAPA_1c38830 f2edf9d1be6b4b062e1e2f85c79f3f21 410 SUPERFAMILY SSF48317 2 173 8.76E-23 T 12-10-2018 IPR036938 Phosphatidic acid phosphatase type 2/haloperoxidase superfamily VAPA_1c38830 f2edf9d1be6b4b062e1e2f85c79f3f21 410 Gene3D G3DSA:1.20.144.10 86 182 7.9E-16 T 12-10-2018 VAPA_1c38830 f2edf9d1be6b4b062e1e2f85c79f3f21 410 Pfam PF01569 PAP2 superfamily 56 166 9.3E-16 T 12-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase VAPA_1c38830 f2edf9d1be6b4b062e1e2f85c79f3f21 410 SMART SM00014 54 164 5.4E-11 T 12-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase VAPA_1c31230 0640f1888e5847239e745d82b29f1ce8 335 PIRSF PIRSF006431 2 327 5.0E-82 T 12-10-2018 IPR005944 Proline iminopeptidase GO:0004177|GO:0005737|GO:0006508 KEGG: 00330+3.4.11.5 VAPA_1c31230 0640f1888e5847239e745d82b29f1ce8 335 Pfam PF00561 alpha/beta hydrolase fold 40 306 3.1E-23 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 VAPA_1c31230 0640f1888e5847239e745d82b29f1ce8 335 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 65 76 2.2E-10 T 12-10-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 VAPA_1c31230 0640f1888e5847239e745d82b29f1ce8 335 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 39 47 2.2E-10 T 12-10-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 VAPA_1c31230 0640f1888e5847239e745d82b29f1ce8 335 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 108 122 2.2E-10 T 12-10-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 VAPA_1c31230 0640f1888e5847239e745d82b29f1ce8 335 Gene3D G3DSA:3.40.50.1820 4 326 7.8E-76 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c31230 0640f1888e5847239e745d82b29f1ce8 335 SUPERFAMILY SSF53474 6 309 9.46E-46 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c37390 7f519947ddd5d3e74f7873fca1b18f15 321 Gene3D G3DSA:2.60.40.1590 71 165 9.6E-19 T 12-10-2018 VAPA_1c37390 7f519947ddd5d3e74f7873fca1b18f15 321 Gene3D G3DSA:2.70.70.10 166 321 1.4E-47 T 12-10-2018 IPR011055 Duplicated hybrid motif VAPA_1c37390 7f519947ddd5d3e74f7873fca1b18f15 321 Pfam PF01551 Peptidase family M23 221 315 2.9E-26 T 12-10-2018 IPR016047 Peptidase M23 VAPA_1c37390 7f519947ddd5d3e74f7873fca1b18f15 321 SUPERFAMILY SSF51261 167 318 9.94E-47 T 12-10-2018 IPR011055 Duplicated hybrid motif VAPA_2c09010 7e539ec65e9157f4d45013f434c926c2 128 SUPERFAMILY SSF82784 15 127 1.83E-29 T 12-10-2018 IPR036102 OsmC/Ohr superfamily VAPA_2c09010 7e539ec65e9157f4d45013f434c926c2 128 Pfam PF02566 OsmC-like protein 35 125 8.5E-14 T 12-10-2018 IPR003718 OsmC/Ohr family VAPA_2c09010 7e539ec65e9157f4d45013f434c926c2 128 Gene3D G3DSA:3.30.300.20 4 128 9.1E-28 T 12-10-2018 IPR015946 K homology domain-like, alpha/beta VAPA_2c07760 344549ffe16d87346031988096fb5760 265 Gene3D G3DSA:3.40.30.10 60 214 2.2E-5 T 12-10-2018 VAPA_2c07760 344549ffe16d87346031988096fb5760 265 SUPERFAMILY SSF52833 61 161 5.36E-6 T 12-10-2018 IPR036249 Thioredoxin-like superfamily VAPA_2c07760 344549ffe16d87346031988096fb5760 265 Pfam PF05988 Bacterial protein of unknown function (DUF899) 12 245 1.4E-94 T 12-10-2018 IPR010296 Protein of unknown function DUF899, thioredoxin-like VAPA_1c20860 f685eec6a89b3655e76c3a2d5bdcb991 331 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 56 324 4.2E-66 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c20860 f685eec6a89b3655e76c3a2d5bdcb991 331 SUPERFAMILY SSF53850 38 278 1.09E-10 T 12-10-2018 VAPA_1c20860 f685eec6a89b3655e76c3a2d5bdcb991 331 Gene3D G3DSA:3.40.190.10 131 252 1.4E-85 T 12-10-2018 VAPA_1c20860 f685eec6a89b3655e76c3a2d5bdcb991 331 PIRSF PIRSF017082 1 326 1.1E-80 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c20860 f685eec6a89b3655e76c3a2d5bdcb991 331 Gene3D G3DSA:3.40.190.150 35 313 1.4E-85 T 12-10-2018 VAPA_1c27490 6ad2a9fbbe9177a4c8e71dce751f4673 284 Pfam PF01739 CheR methyltransferase, SAM binding domain 86 270 2.3E-35 T 12-10-2018 IPR022642 MCP methyltransferase, CheR-type, SAM-binding domain, C-terminal VAPA_1c27490 6ad2a9fbbe9177a4c8e71dce751f4673 284 SUPERFAMILY SSF53335 85 263 9.3E-39 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase VAPA_1c27490 6ad2a9fbbe9177a4c8e71dce751f4673 284 SMART SM00138 18 281 1.2E-31 T 12-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 VAPA_1c27490 6ad2a9fbbe9177a4c8e71dce751f4673 284 PRINTS PR00996 Glutamate methyltransferase family signature 145 161 2.1E-22 T 12-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 VAPA_1c27490 6ad2a9fbbe9177a4c8e71dce751f4673 284 PRINTS PR00996 Glutamate methyltransferase family signature 219 233 2.1E-22 T 12-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 VAPA_1c27490 6ad2a9fbbe9177a4c8e71dce751f4673 284 PRINTS PR00996 Glutamate methyltransferase family signature 77 89 2.1E-22 T 12-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 VAPA_1c27490 6ad2a9fbbe9177a4c8e71dce751f4673 284 PRINTS PR00996 Glutamate methyltransferase family signature 238 261 2.1E-22 T 12-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 VAPA_1c27490 6ad2a9fbbe9177a4c8e71dce751f4673 284 PRINTS PR00996 Glutamate methyltransferase family signature 113 133 2.1E-22 T 12-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 VAPA_1c27490 6ad2a9fbbe9177a4c8e71dce751f4673 284 Pfam PF03705 CheR methyltransferase, all-alpha domain 20 71 2.6E-8 T 12-10-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal VAPA_1c27490 6ad2a9fbbe9177a4c8e71dce751f4673 284 Gene3D G3DSA:3.40.50.150 83 283 1.1E-52 T 12-10-2018 VAPA_1c52010 db05ea3f01ac5796b19c8a0b87fd297c 415 Gene3D G3DSA:3.30.300.30 320 413 4.3E-15 T 12-10-2018 VAPA_1c52010 db05ea3f01ac5796b19c8a0b87fd297c 415 Pfam PF00501 AMP-binding enzyme 153 280 1.6E-10 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 VAPA_1c52010 db05ea3f01ac5796b19c8a0b87fd297c 415 SUPERFAMILY SSF56801 112 385 1.7E-29 T 12-10-2018 VAPA_1c52010 db05ea3f01ac5796b19c8a0b87fd297c 415 Gene3D G3DSA:3.40.50.12780 2 319 2.7E-65 T 12-10-2018 VAPA_1c06960 ef21615e7ea4f69ab7cb3d7e28d77cdf 483 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 249 256 - T 12-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 VAPA_1c06960 ef21615e7ea4f69ab7cb3d7e28d77cdf 483 Gene3D G3DSA:3.40.309.10 253 483 1.5E-76 T 12-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 VAPA_1c06960 ef21615e7ea4f69ab7cb3d7e28d77cdf 483 Gene3D G3DSA:3.40.605.10 1 252 1.2E-74 T 12-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 VAPA_1c06960 ef21615e7ea4f69ab7cb3d7e28d77cdf 483 SUPERFAMILY SSF53720 2 476 1.83E-142 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 VAPA_1c06960 ef21615e7ea4f69ab7cb3d7e28d77cdf 483 Pfam PF00171 Aldehyde dehydrogenase family 17 472 1.9E-148 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 VAPA_2c06920 09273ee519448cc1f83f0db9d99ef9ab 350 Pfam PF02653 Branched-chain amino acid transport system / permease component 45 313 6.2E-30 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 VAPA_1c37670 54065db28c1e7d5ef7a743b13bf97c57 299 Pfam PF05661 Protein of unknown function (DUF808) 3 290 2.7E-114 T 12-10-2018 IPR008526 Inner membrane protein YedI VAPA_1c37670 54065db28c1e7d5ef7a743b13bf97c57 299 PIRSF PIRSF016660 1 299 7.6E-119 T 12-10-2018 IPR008526 Inner membrane protein YedI VAPA_2c04370 947f8a85fd5419370f4a99e2f47181f7 63 Pfam PF11127 Protein of unknown function (DUF2892) 1 58 1.3E-14 T 12-10-2018 IPR021309 Protein of unknown function DUF2892 VAPA_1c00190 efce131c9fbd75f52258aa48812a5956 424 Gene3D G3DSA:1.10.3810.10 239 409 5.4E-45 T 12-10-2018 IPR036950 Penicillin binding protein transglycosylase domain KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 VAPA_1c00190 efce131c9fbd75f52258aa48812a5956 424 SUPERFAMILY SSF53955 242 393 6.47E-44 T 12-10-2018 IPR023346 Lysozyme-like domain superfamily VAPA_1c00190 efce131c9fbd75f52258aa48812a5956 424 Pfam PF00912 Transglycosylase 243 376 2.2E-43 T 12-10-2018 IPR001264 Glycosyl transferase, family 51 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 VAPA_1c48220 1c7fc61eea2c1c069621ed7b1208dfdb 163 Pfam PF04773 FecR protein 71 162 8.8E-13 T 12-10-2018 IPR006860 FecR protein VAPA_1c22710 5c2fc3cfbf15924936ec7b20f25cc484 286 Pfam PF07519 Tannase and feruloyl esterase 6 281 3.8E-60 T 12-10-2018 IPR011118 Tannase/feruloyl esterase MetaCyc: PWY-6784 VAPA_1c08640 87bf700be827f9b47e1454b069f2126c 684 Pfam PF05378 Hydantoinase/oxoprolinase N-terminal region 10 182 2.2E-48 T 12-10-2018 IPR008040 Hydantoinaseoxoprolinase, N-terminal Reactome: R-HSA-174403|Reactome: R-HSA-5578998 VAPA_1c08640 87bf700be827f9b47e1454b069f2126c 684 Pfam PF01968 Hydantoinase/oxoprolinase 203 493 4.3E-89 T 12-10-2018 IPR002821 Hydantoinase A/oxoprolinase GO:0016787 Reactome: R-HSA-174403|Reactome: R-HSA-5578998 VAPA_1c25030 942e1a1f7dd6716576e51737e3a04b15 160 Pfam PF06271 RDD family 1 148 6.8E-20 T 12-10-2018 IPR010432 RDD VAPA_1c05050 c210c5c3b8b7b9c40bb3e6d7dcc1a49f 431 TIGRFAM TIGR00407 proA: glutamate-5-semialdehyde dehydrogenase 17 420 1.1E-144 T 12-10-2018 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 VAPA_1c05050 c210c5c3b8b7b9c40bb3e6d7dcc1a49f 431 SUPERFAMILY SSF53720 9 430 5.89E-112 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 VAPA_1c05050 c210c5c3b8b7b9c40bb3e6d7dcc1a49f 431 Pfam PF00171 Aldehyde dehydrogenase family 27 284 4.2E-14 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 VAPA_1c05050 c210c5c3b8b7b9c40bb3e6d7dcc1a49f 431 Pfam PF00171 Aldehyde dehydrogenase family 323 393 2.4E-6 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 VAPA_1c05050 c210c5c3b8b7b9c40bb3e6d7dcc1a49f 431 Gene3D G3DSA:3.40.309.10 230 388 7.8E-159 T 12-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 VAPA_1c05050 c210c5c3b8b7b9c40bb3e6d7dcc1a49f 431 Hamap MF_00412 Gamma-glutamyl phosphate reductase [proA]. 9 430 39.757 T 12-10-2018 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 VAPA_1c05050 c210c5c3b8b7b9c40bb3e6d7dcc1a49f 431 Gene3D G3DSA:3.40.605.10 16 427 7.8E-159 T 12-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 VAPA_1c05050 c210c5c3b8b7b9c40bb3e6d7dcc1a49f 431 ProSitePatterns PS01223 Gamma-glutamyl phosphate reductase signature. 337 358 - T 12-10-2018 IPR020593 Gamma-glutamyl phosphate reductase GPR, conserved site GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 VAPA_1c05050 c210c5c3b8b7b9c40bb3e6d7dcc1a49f 431 PIRSF PIRSF000151 3 431 4.6E-167 T 12-10-2018 IPR012134 Glutamate-5-semialdehyde dehydrogenase GO:0004350|GO:0006561|GO:0050661|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922 VAPA_1c06010 03a6f309314fad7f48cdeb2cb944ff79 185 SUPERFAMILY SSF141452 40 175 1.44E-8 T 12-10-2018 IPR036624 Hcp1-like superfamily VAPA_1c06010 03a6f309314fad7f48cdeb2cb944ff79 185 Pfam PF05638 Type VI secretion system effector, Hcp 37 163 4.2E-5 T 12-10-2018 IPR008514 Type VI secretion system effector, Hcp VAPA_1c06010 03a6f309314fad7f48cdeb2cb944ff79 185 Gene3D G3DSA:2.30.110.20 29 183 4.3E-8 T 12-10-2018 IPR036624 Hcp1-like superfamily VAPA_1c06620 b1c768ad995e68d27f15ce276f5bb0d4 142 SUPERFAMILY SSF54593 4 139 2.34E-18 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase VAPA_1c06620 b1c768ad995e68d27f15ce276f5bb0d4 142 Gene3D G3DSA:3.10.180.10 1 138 1.9E-18 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase VAPA_1c06620 b1c768ad995e68d27f15ce276f5bb0d4 142 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 4 134 6.6E-7 T 12-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain VAPA_1c24880 26211b884945ef0f0cee1c60f1e0e22b 647 Gene3D G3DSA:3.40.47.10 226 374 1.9E-25 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 VAPA_1c24880 26211b884945ef0f0cee1c60f1e0e22b 647 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 128 198 5.8E-5 T 12-10-2018 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 VAPA_1c24880 26211b884945ef0f0cee1c60f1e0e22b 647 Pfam PF14518 Iron-containing redox enzyme 454 600 2.1E-7 T 12-10-2018 VAPA_1c24880 26211b884945ef0f0cee1c60f1e0e22b 647 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 284 358 8.3E-8 T 12-10-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 VAPA_1c24880 26211b884945ef0f0cee1c60f1e0e22b 647 Gene3D G3DSA:1.20.910.10 422 644 4.0E-39 T 12-10-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 VAPA_1c24880 26211b884945ef0f0cee1c60f1e0e22b 647 Gene3D G3DSA:3.40.47.10 7 200 8.5E-37 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 VAPA_1c24880 26211b884945ef0f0cee1c60f1e0e22b 647 SUPERFAMILY SSF53901 257 371 1.68E-15 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 VAPA_1c24880 26211b884945ef0f0cee1c60f1e0e22b 647 SUPERFAMILY SSF53901 7 198 1.82E-28 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 VAPA_1c24880 26211b884945ef0f0cee1c60f1e0e22b 647 SUPERFAMILY SSF48613 418 636 1.13E-26 T 12-10-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 VAPA_2c10780 202e48079de4381f051c002265486e95 410 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 137 232 3.6E-20 T 12-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 VAPA_2c10780 202e48079de4381f051c002265486e95 410 Gene3D G3DSA:2.40.110.10 136 250 4.2E-48 T 12-10-2018 VAPA_2c10780 202e48079de4381f051c002265486e95 410 SUPERFAMILY SSF56645 6 263 1.18E-62 T 12-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 VAPA_2c10780 202e48079de4381f051c002265486e95 410 Gene3D G3DSA:1.20.140.10 251 406 9.2E-39 T 12-10-2018 VAPA_2c10780 202e48079de4381f051c002265486e95 410 SUPERFAMILY SSF47203 248 403 2.09E-43 T 12-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 VAPA_2c10780 202e48079de4381f051c002265486e95 410 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 250 398 4.0E-36 T 12-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 VAPA_2c10780 202e48079de4381f051c002265486e95 410 Gene3D G3DSA:1.10.540.10 1 135 5.7E-45 T 12-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 VAPA_2c10780 202e48079de4381f051c002265486e95 410 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 7 133 6.7E-14 T 12-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 VAPA_2c13040 f2e851e9d6966550b79f353f26cd77fc 161 SUPERFAMILY SSF56349 113 144 6.67E-5 T 12-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 VAPA_2c13040 f2e851e9d6966550b79f353f26cd77fc 161 Pfam PF13586 Transposase DDE domain 38 114 7.4E-12 T 12-10-2018 IPR025668 Transposase DDE domain VAPA_1c40610 e7e62034526272df848fca2944db6871 266 SUPERFAMILY SSF51735 10 265 1.91E-72 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c40610 e7e62034526272df848fca2944db6871 266 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 139 147 1.1E-7 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c40610 e7e62034526272df848fca2944db6871 266 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 163 182 1.1E-7 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c40610 e7e62034526272df848fca2944db6871 266 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 79 90 1.1E-7 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c40610 e7e62034526272df848fca2944db6871 266 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 263 6.2E-57 T 12-10-2018 VAPA_1c40610 e7e62034526272df848fca2944db6871 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 2.5E-38 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c40610 e7e62034526272df848fca2944db6871 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 2.5E-38 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c40610 e7e62034526272df848fca2944db6871 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 183 200 2.5E-38 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c40610 e7e62034526272df848fca2944db6871 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 163 182 2.5E-38 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c40610 e7e62034526272df848fca2944db6871 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 133 149 2.5E-38 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c40610 e7e62034526272df848fca2944db6871 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 227 247 2.5E-38 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c40610 e7e62034526272df848fca2944db6871 266 Gene3D G3DSA:3.40.50.720 8 266 2.6E-79 T 12-10-2018 VAPA_1c40020 cb0f0c8cbc1e672ae36a636812f8eb27 344 Gene3D G3DSA:3.40.50.2300 137 324 1.9E-118 T 12-10-2018 VAPA_1c40020 cb0f0c8cbc1e672ae36a636812f8eb27 344 Pfam PF02608 ABC transporter substrate-binding protein PnrA-like 34 315 9.2E-55 T 12-10-2018 IPR003760 ABC transporter substrate-binding protein PnrA-like GO:0005886 VAPA_1c40020 cb0f0c8cbc1e672ae36a636812f8eb27 344 SUPERFAMILY SSF53822 33 259 5.1E-5 T 12-10-2018 IPR028082 Periplasmic binding protein-like I VAPA_1c40020 cb0f0c8cbc1e672ae36a636812f8eb27 344 Gene3D G3DSA:3.40.50.2300 34 290 1.9E-118 T 12-10-2018 VAPA_1c46460 f0c44f74b05c7feb0af2a5914e67c799 395 Pfam PF05762 VWA domain containing CoxE-like protein 189 277 5.6E-9 T 12-10-2018 IPR008912 Uncharacterised protein family CoxE-like VAPA_1c13810 74bf72ae8ef76d6cfb5dfcf1399bc9db 384 Gene3D G3DSA:3.30.390.10 5 370 2.5E-108 T 12-10-2018 IPR029017 Enolase-like, N-terminal VAPA_1c13810 74bf72ae8ef76d6cfb5dfcf1399bc9db 384 SUPERFAMILY SSF54826 1 127 1.84E-31 T 12-10-2018 VAPA_1c13810 74bf72ae8ef76d6cfb5dfcf1399bc9db 384 ProSitePatterns PS00908 Mandelate racemase / muconate lactonizing enzyme family signature 1. 98 123 - T 12-10-2018 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 VAPA_1c13810 74bf72ae8ef76d6cfb5dfcf1399bc9db 384 SMART SM00922 142 252 2.3E-22 T 12-10-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal VAPA_1c13810 74bf72ae8ef76d6cfb5dfcf1399bc9db 384 SUPERFAMILY SSF51604 111 372 6.81E-67 T 12-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily VAPA_1c13810 74bf72ae8ef76d6cfb5dfcf1399bc9db 384 Gene3D G3DSA:3.20.20.120 117 365 2.5E-108 T 12-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily VAPA_1c13810 74bf72ae8ef76d6cfb5dfcf1399bc9db 384 Pfam PF13378 Enolase C-terminal domain-like 145 367 3.1E-57 T 12-10-2018 IPR029065 Enolase C-terminal domain-like VAPA_1c13810 74bf72ae8ef76d6cfb5dfcf1399bc9db 384 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 8 123 2.1E-17 T 12-10-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain VAPA_1c32490 a3ac11f3379893d47eef2d6a58c7310d 387 SUPERFAMILY SSF54373 177 277 6.28E-12 T 12-10-2018 VAPA_1c32490 a3ac11f3379893d47eef2d6a58c7310d 387 Pfam PF01494 FAD binding domain 7 348 7.0E-24 T 12-10-2018 IPR002938 FAD-binding domain GO:0071949 VAPA_1c32490 a3ac11f3379893d47eef2d6a58c7310d 387 Gene3D G3DSA:3.50.50.60 7 381 2.8E-118 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c32490 a3ac11f3379893d47eef2d6a58c7310d 387 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 287 302 5.0E-17 T 12-10-2018 VAPA_1c32490 a3ac11f3379893d47eef2d6a58c7310d 387 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 7 29 5.0E-17 T 12-10-2018 VAPA_1c32490 a3ac11f3379893d47eef2d6a58c7310d 387 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 152 167 5.0E-17 T 12-10-2018 VAPA_1c32490 a3ac11f3379893d47eef2d6a58c7310d 387 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 302 318 5.0E-17 T 12-10-2018 VAPA_1c32490 a3ac11f3379893d47eef2d6a58c7310d 387 SUPERFAMILY SSF51905 8 372 2.72E-55 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c04510 9428f90f107bcc8839a82927a5c7217e 346 Gene3D G3DSA:3.40.50.2300 52 319 2.2E-66 T 12-10-2018 VAPA_1c04510 9428f90f107bcc8839a82927a5c7217e 346 Gene3D G3DSA:3.40.50.2300 143 328 2.2E-66 T 12-10-2018 VAPA_1c04510 9428f90f107bcc8839a82927a5c7217e 346 Pfam PF13407 Periplasmic binding protein domain 50 289 1.1E-45 T 12-10-2018 IPR025997 Periplasmic binding protein VAPA_1c04510 9428f90f107bcc8839a82927a5c7217e 346 SUPERFAMILY SSF53822 42 312 2.52E-52 T 12-10-2018 IPR028082 Periplasmic binding protein-like I VAPA_2c03360 6511985653db3b650d01990b9a16c79b 124 SUPERFAMILY SSF109635 3 85 2.09E-7 T 12-10-2018 IPR037187 DksA, N-terminal domain superfamily VAPA_2c03360 6511985653db3b650d01990b9a16c79b 124 Gene3D G3DSA:1.20.120.910 1 124 2.2E-24 T 12-10-2018 VAPA_2c03360 6511985653db3b650d01990b9a16c79b 124 Pfam PF01258 Prokaryotic dksA/traR C4-type zinc finger 85 119 5.7E-12 T 12-10-2018 IPR000962 Zinc finger, DksA/TraR C4-type GO:0008270 VAPA_2c03360 6511985653db3b650d01990b9a16c79b 124 SUPERFAMILY SSF57716 87 122 6.65E-9 T 12-10-2018 VAPA_1c37400 513c20d92d005bfd6991409498b512c1 311 Pfam PF04952 Succinylglutamate desuccinylase / Aspartoacylase family 36 308 2.2E-10 T 12-10-2018 IPR007036 Succinylglutamate desuccinylase/aspartoacylase GO:0016788 VAPA_1c37400 513c20d92d005bfd6991409498b512c1 311 SUPERFAMILY SSF53187 13 307 2.05E-46 T 12-10-2018 VAPA_1c37400 513c20d92d005bfd6991409498b512c1 311 Gene3D G3DSA:3.40.630.10 4 311 1.0E-56 T 12-10-2018 VAPA_1c05480 bc4ac5d37cb55476887624875216276c 213 Pfam PF01810 LysE type translocator 17 208 4.0E-29 T 12-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 VAPA_1c51800 beac44dea16381ee6a0c6713b0256c5d 232 SMART SM00862 154 230 1.9E-22 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 VAPA_1c51800 beac44dea16381ee6a0c6713b0256c5d 232 SUPERFAMILY SSF52172 1 188 4.1E-36 T 12-10-2018 IPR011006 CheY-like superfamily VAPA_1c51800 beac44dea16381ee6a0c6713b0256c5d 232 Pfam PF00072 Response regulator receiver domain 7 115 3.9E-24 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_1c51800 beac44dea16381ee6a0c6713b0256c5d 232 SMART SM00448 4 114 6.1E-37 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_1c51800 beac44dea16381ee6a0c6713b0256c5d 232 Gene3D G3DSA:3.40.50.2300 2 123 1.1E-31 T 12-10-2018 VAPA_1c51800 beac44dea16381ee6a0c6713b0256c5d 232 Pfam PF00486 Transcriptional regulatory protein, C terminal 154 230 1.2E-21 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 VAPA_1c51800 beac44dea16381ee6a0c6713b0256c5d 232 Gene3D G3DSA:1.10.10.10 126 231 2.0E-30 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c34760 00d25f6706ad0fbdef1d4502aba915bb 208 Gene3D G3DSA:1.10.3210.10 20 179 3.2E-6 T 12-10-2018 VAPA_1c34760 00d25f6706ad0fbdef1d4502aba915bb 208 PIRSF PIRSF035170 1 208 5.2E-52 T 12-10-2018 IPR009218 Predicted HD phosphohydrolase VAPA_1c34760 00d25f6706ad0fbdef1d4502aba915bb 208 SUPERFAMILY SSF109604 28 197 4.71E-22 T 12-10-2018 VAPA_1c21650 46b49962cd0f041f3935d6c0690eb235 323 Gene3D G3DSA:3.40.190.10 126 247 5.1E-101 T 12-10-2018 VAPA_1c21650 46b49962cd0f041f3935d6c0690eb235 323 PIRSF PIRSF017082 1 323 1.1E-73 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c21650 46b49962cd0f041f3935d6c0690eb235 323 Gene3D G3DSA:3.40.190.150 28 313 5.1E-101 T 12-10-2018 VAPA_1c21650 46b49962cd0f041f3935d6c0690eb235 323 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 47 319 2.9E-77 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c21650 46b49962cd0f041f3935d6c0690eb235 323 SUPERFAMILY SSF53850 113 278 1.0E-11 T 12-10-2018 VAPA_1c18450 eb3156e025fd4353ae9bc6929badbac7 329 Gene3D G3DSA:3.40.190.10 130 253 1.8E-97 T 12-10-2018 VAPA_1c18450 eb3156e025fd4353ae9bc6929badbac7 329 SUPERFAMILY SSF53850 119 293 1.5E-9 T 12-10-2018 VAPA_1c18450 eb3156e025fd4353ae9bc6929badbac7 329 PIRSF PIRSF017082 4 329 3.6E-69 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c18450 eb3156e025fd4353ae9bc6929badbac7 329 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 52 325 1.9E-76 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c18450 eb3156e025fd4353ae9bc6929badbac7 329 Gene3D G3DSA:3.40.190.150 34 319 1.8E-97 T 12-10-2018 VAPA_2c03000 515147bcd3ce623430b6f4fa50fa5989 324 Gene3D G3DSA:3.40.190.10 123 246 3.8E-102 T 12-10-2018 VAPA_2c03000 515147bcd3ce623430b6f4fa50fa5989 324 Gene3D G3DSA:3.40.190.150 25 314 3.8E-102 T 12-10-2018 VAPA_2c03000 515147bcd3ce623430b6f4fa50fa5989 324 PIRSF PIRSF017082 2 323 2.5E-77 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_2c03000 515147bcd3ce623430b6f4fa50fa5989 324 SUPERFAMILY SSF53850 110 279 1.45E-15 T 12-10-2018 VAPA_2c03000 515147bcd3ce623430b6f4fa50fa5989 324 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 45 320 6.2E-78 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c19870 a4db0251663183ace2996fa2f4d445d5 109 Gene3D G3DSA:1.10.10.10 2 94 7.0E-21 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c19870 a4db0251663183ace2996fa2f4d445d5 109 SUPERFAMILY SSF46785 3 94 7.66E-23 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c19870 a4db0251663183ace2996fa2f4d445d5 109 Pfam PF12840 Helix-turn-helix domain 11 70 1.9E-16 T 12-10-2018 VAPA_1c19870 a4db0251663183ace2996fa2f4d445d5 109 SMART SM00418 9 90 2.6E-14 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 VAPA_1c19870 a4db0251663183ace2996fa2f4d445d5 109 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 46 61 9.0E-9 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 VAPA_1c19870 a4db0251663183ace2996fa2f4d445d5 109 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 61 76 9.0E-9 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 VAPA_1c19870 a4db0251663183ace2996fa2f4d445d5 109 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 11 26 9.0E-9 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 VAPA_1c21680 a3e643313790fac01fd526aa7c757acc 297 SUPERFAMILY SSF53850 91 293 7.6E-45 T 12-10-2018 VAPA_1c21680 a3e643313790fac01fd526aa7c757acc 297 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 9 67 2.1E-15 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c21680 a3e643313790fac01fd526aa7c757acc 297 Gene3D G3DSA:3.40.190.10 91 293 2.9E-66 T 12-10-2018 VAPA_1c21680 a3e643313790fac01fd526aa7c757acc 297 SUPERFAMILY SSF46785 5 85 1.17E-17 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c21680 a3e643313790fac01fd526aa7c757acc 297 Gene3D G3DSA:3.40.190.10 172 268 2.9E-66 T 12-10-2018 VAPA_1c21680 a3e643313790fac01fd526aa7c757acc 297 Pfam PF03466 LysR substrate binding domain 96 296 2.7E-32 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_1c21680 a3e643313790fac01fd526aa7c757acc 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 35 45 9.9E-5 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c21680 a3e643313790fac01fd526aa7c757acc 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 24 35 9.9E-5 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c21680 a3e643313790fac01fd526aa7c757acc 297 Gene3D G3DSA:1.10.10.10 1 90 5.7E-32 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c41880 6a8ac0cc388c077280df31b2932f400a 240 SUPERFAMILY SSF161098 21 208 4.45E-43 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c41880 6a8ac0cc388c077280df31b2932f400a 240 Gene3D G3DSA:1.10.3720.10 14 226 8.0E-54 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c41880 6a8ac0cc388c077280df31b2932f400a 240 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 23 116 2.3E-27 T 12-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 VAPA_1c41880 6a8ac0cc388c077280df31b2932f400a 240 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 40 223 3.1E-21 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 VAPA_1c16580 70dcfb8a0971aa385249593e9b946e0a 420 Pfam PF12704 MacB-like periplasmic core domain 20 193 4.7E-12 T 12-10-2018 IPR025857 MacB-like periplasmic core domain VAPA_1c16580 70dcfb8a0971aa385249593e9b946e0a 420 Pfam PF02687 FtsX-like permease family 318 408 1.1E-7 T 12-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 VAPA_1c45840 d9361076ad9a1b5ea00a331265d15bf8 139 SUPERFAMILY SSF54593 1 133 7.77E-35 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase VAPA_1c45840 d9361076ad9a1b5ea00a331265d15bf8 139 Gene3D G3DSA:3.10.180.10 8 137 3.3E-49 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase VAPA_1c45840 d9361076ad9a1b5ea00a331265d15bf8 139 Pfam PF06983 3-demethylubiquinone-9 3-methyltransferase 4 132 1.6E-8 T 12-10-2018 IPR028973 PhnB-like VAPA_1c12330 06d702294f254a7cac35e9f3c6e800bf 293 PIRSF PIRSF016020 9 293 1.3E-54 T 12-10-2018 IPR025532 Glucose-6-phosphate 1-epimerase KEGG: 00010+5.1.3.15 VAPA_1c12330 06d702294f254a7cac35e9f3c6e800bf 293 Gene3D G3DSA:2.70.98.10 26 292 1.3E-78 T 12-10-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 VAPA_1c12330 06d702294f254a7cac35e9f3c6e800bf 293 SUPERFAMILY SSF74650 18 290 2.32E-55 T 12-10-2018 IPR011013 Galactose mutarotase-like domain superfamily GO:0003824|GO:0005975|GO:0030246 VAPA_1c12330 06d702294f254a7cac35e9f3c6e800bf 293 Pfam PF01263 Aldose 1-epimerase 35 290 1.5E-37 T 12-10-2018 IPR008183 Aldose 1-/Glucose-6-phosphate 1-epimerase GO:0005975|GO:0016853 VAPA_1c10630 a2dbb5dd04ece8308e8827e86c8a4e47 334 Gene3D G3DSA:3.90.25.10 167 307 6.8E-92 T 12-10-2018 VAPA_1c10630 a2dbb5dd04ece8308e8827e86c8a4e47 334 Pfam PF05368 NmrA-like family 10 249 2.4E-43 T 12-10-2018 IPR008030 NmrA-like domain Reactome: R-HSA-70635 VAPA_1c10630 a2dbb5dd04ece8308e8827e86c8a4e47 334 Gene3D G3DSA:3.40.50.720 9 300 6.8E-92 T 12-10-2018 VAPA_1c10630 a2dbb5dd04ece8308e8827e86c8a4e47 334 SUPERFAMILY SSF51735 7 305 1.84E-53 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c13010 57648117d676802d0c960ec24b2e328d 336 Gene3D G3DSA:1.20.1260.10 26 336 4.5E-130 T 12-10-2018 IPR012347 Ferritin-like VAPA_1c13010 57648117d676802d0c960ec24b2e328d 336 SUPERFAMILY SSF47240 53 296 5.35E-79 T 12-10-2018 IPR009078 Ferritin-like superfamily VAPA_1c13010 57648117d676802d0c960ec24b2e328d 336 TIGRFAM TIGR02156 PA_CoA_Oxy1: phenylacetate-CoA oxygenase, PaaG subunit 33 322 1.9E-160 T 12-10-2018 IPR011881 1,2-phenylacetyl-CoA epoxidase, subunit A GO:0010124|GO:0097266 KEGG: 00360+1.14.13.149 VAPA_1c13010 57648117d676802d0c960ec24b2e328d 336 Pfam PF05138 Phenylacetic acid catabolic protein 43 318 7.0E-101 T 12-10-2018 IPR007814 1,2-phenylacetyl-CoA epoxidase, subunit A/C GO:0010124 VAPA_1c05950 01ec0fbf05362614199228270de8d921 207 Pfam PF09867 Uncharacterized protein conserved in bacteria (DUF2094) 12 148 6.5E-41 T 12-10-2018 IPR017748 T6S-associated protein TagF VAPA_1c05950 01ec0fbf05362614199228270de8d921 207 TIGRFAM TIGR03373 VI_minor_4: type VI secretion-associated protein, BMA_A0400 family 12 147 7.1E-37 T 12-10-2018 IPR017748 T6S-associated protein TagF VAPA_1c05950 01ec0fbf05362614199228270de8d921 207 Gene3D G3DSA:3.40.1730.10 9 206 2.1E-48 T 12-10-2018 IPR038225 T6S-associated protein TagF superfamily VAPA_1c53800 35df815f2637eda78691632b85a26b7b 208 Pfam PF13649 Methyltransferase domain 36 129 9.8E-9 T 12-10-2018 VAPA_1c53800 35df815f2637eda78691632b85a26b7b 208 Gene3D G3DSA:3.40.50.150 8 187 2.9E-17 T 12-10-2018 VAPA_1c53800 35df815f2637eda78691632b85a26b7b 208 SUPERFAMILY SSF53335 14 169 4.11E-20 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase VAPA_2c12720 bedbd3f273193f2a5f61a7ce53cfd945 175 Pfam PF06803 Protein of unknown function (DUF1232) 33 68 1.3E-5 T 12-10-2018 IPR010652 Domain of unknown function DUF1232 MetaCyc: PWY-7511 VAPA_2c00080 fa8453a2e0b4ddb7d258a086d68f78f5 172 Pfam PF13412 Winged helix-turn-helix DNA-binding 13 55 3.8E-16 T 12-10-2018 VAPA_2c00080 fa8453a2e0b4ddb7d258a086d68f78f5 172 SMART SM00344 8 117 1.4E-37 T 12-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 VAPA_2c00080 fa8453a2e0b4ddb7d258a086d68f78f5 172 ProSitePatterns PS00519 AsnC-type HTH domain signature. 26 52 - T 12-10-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site VAPA_2c00080 fa8453a2e0b4ddb7d258a086d68f78f5 172 Gene3D G3DSA:1.10.10.10 9 58 5.6E-21 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_2c00080 fa8453a2e0b4ddb7d258a086d68f78f5 172 SUPERFAMILY SSF46785 4 95 2.57E-17 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_2c00080 fa8453a2e0b4ddb7d258a086d68f78f5 172 Gene3D G3DSA:3.30.70.920 59 154 7.2E-24 T 12-10-2018 VAPA_2c00080 fa8453a2e0b4ddb7d258a086d68f78f5 172 SUPERFAMILY SSF54909 68 157 2.55E-21 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel VAPA_2c00080 fa8453a2e0b4ddb7d258a086d68f78f5 172 Pfam PF01037 Lrp/AsnC ligand binding domain 75 148 8.5E-23 T 12-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain VAPA_2c00080 fa8453a2e0b4ddb7d258a086d68f78f5 172 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 35 54 6.4E-13 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 VAPA_2c00080 fa8453a2e0b4ddb7d258a086d68f78f5 172 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 24 35 6.4E-13 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 VAPA_2c00080 fa8453a2e0b4ddb7d258a086d68f78f5 172 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 8 24 6.4E-13 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 VAPA_1c35680 f4cae888bb2dddf46924d032dcc52321 321 Pfam PF08331 Domain of unknown function (DUF1730) 22 107 1.0E-21 T 12-10-2018 IPR013542 Domain of unknown function DUF1730 MetaCyc: PWY-6700 VAPA_1c35680 f4cae888bb2dddf46924d032dcc52321 321 TIGRFAM TIGR00276 TIGR00276: epoxyqueuosine reductase 2 317 2.5E-129 T 12-10-2018 IPR004453 Epoxyqueuosine reductase QueG GO:0008033|GO:0008616|GO:0016491 MetaCyc: PWY-6700 VAPA_1c35680 f4cae888bb2dddf46924d032dcc52321 321 SUPERFAMILY SSF54862 137 278 1.84E-17 T 12-10-2018 VAPA_1c35680 f4cae888bb2dddf46924d032dcc52321 321 Pfam PF13484 4Fe-4S double cluster binding domain 159 223 3.7E-20 T 12-10-2018 VAPA_1c35680 f4cae888bb2dddf46924d032dcc52321 321 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 160 171 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site VAPA_1c21780 36a3c60f3ada6a40450c670efd455134 325 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 50 321 2.9E-71 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c21780 36a3c60f3ada6a40450c670efd455134 325 Gene3D G3DSA:3.40.190.150 31 315 1.1E-88 T 12-10-2018 VAPA_1c21780 36a3c60f3ada6a40450c670efd455134 325 Gene3D G3DSA:3.40.190.10 127 250 1.1E-88 T 12-10-2018 VAPA_1c21780 36a3c60f3ada6a40450c670efd455134 325 PIRSF PIRSF017082 1 325 4.3E-69 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c21780 36a3c60f3ada6a40450c670efd455134 325 SUPERFAMILY SSF53850 116 281 3.12E-9 T 12-10-2018 VAPA_1c22440 6ad2c8a7dbba6c14c0140a9a2564932a 315 SUPERFAMILY SSF46785 1 87 1.04E-17 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c22440 6ad2c8a7dbba6c14c0140a9a2564932a 315 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 2.1E-13 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c22440 6ad2c8a7dbba6c14c0140a9a2564932a 315 Pfam PF03466 LysR substrate binding domain 91 294 1.0E-24 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_1c22440 6ad2c8a7dbba6c14c0140a9a2564932a 315 Gene3D G3DSA:1.10.10.10 1 89 1.9E-20 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c22440 6ad2c8a7dbba6c14c0140a9a2564932a 315 Gene3D G3DSA:3.40.190.10 92 286 1.7E-38 T 12-10-2018 VAPA_1c22440 6ad2c8a7dbba6c14c0140a9a2564932a 315 Gene3D G3DSA:3.40.190.10 165 268 1.7E-38 T 12-10-2018 VAPA_1c22440 6ad2c8a7dbba6c14c0140a9a2564932a 315 SUPERFAMILY SSF53850 91 297 2.06E-24 T 12-10-2018 VAPA_1c39360 b051e200b282282f3be78108dd845890 380 SUPERFAMILY SSF53067 143 374 1.0E-70 T 12-10-2018 VAPA_1c39360 b051e200b282282f3be78108dd845890 380 SUPERFAMILY SSF53067 28 179 1.17E-47 T 12-10-2018 VAPA_1c39360 b051e200b282282f3be78108dd845890 380 Pfam PF00871 Acetokinase family 44 368 5.2E-98 T 12-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 VAPA_1c39360 b051e200b282282f3be78108dd845890 380 PIRSF PIRSF000722 7 378 7.0E-125 T 12-10-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 VAPA_1c39360 b051e200b282282f3be78108dd845890 380 Hamap MF_00020 Acetate kinase [ackA]. 1 377 143.195 T 12-10-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 VAPA_1c39360 b051e200b282282f3be78108dd845890 380 Gene3D G3DSA:3.30.420.40 181 379 1.7E-68 T 12-10-2018 VAPA_1c39360 b051e200b282282f3be78108dd845890 380 TIGRFAM TIGR00016 ackA: acetate kinase 43 374 5.5E-98 T 12-10-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 VAPA_1c39360 b051e200b282282f3be78108dd845890 380 Gene3D G3DSA:3.30.420.40 6 179 4.7E-52 T 12-10-2018 VAPA_1c39360 b051e200b282282f3be78108dd845890 380 PRINTS PR00471 Acetate kinase family signature 281 294 6.9E-27 T 12-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 VAPA_1c39360 b051e200b282282f3be78108dd845890 380 PRINTS PR00471 Acetate kinase family signature 355 367 6.9E-27 T 12-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 VAPA_1c39360 b051e200b282282f3be78108dd845890 380 PRINTS PR00471 Acetate kinase family signature 303 319 6.9E-27 T 12-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 VAPA_1c39360 b051e200b282282f3be78108dd845890 380 PRINTS PR00471 Acetate kinase family signature 158 171 6.9E-27 T 12-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 VAPA_1c39360 b051e200b282282f3be78108dd845890 380 PRINTS PR00471 Acetate kinase family signature 187 208 6.9E-27 T 12-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 VAPA_2c11630 f5b9d6e6b76d1e1c1b8f2370721e7f35 270 SUPERFAMILY SSF161098 73 259 5.1E-33 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_2c11630 f5b9d6e6b76d1e1c1b8f2370721e7f35 270 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 99 268 1.4E-18 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 VAPA_2c11630 f5b9d6e6b76d1e1c1b8f2370721e7f35 270 TIGRFAM TIGR01097 PhnE: phosphonate ABC transporter, permease protein PhnE 30 269 7.7E-91 T 12-10-2018 IPR005769 ABC transporter, permease PhnE/PtxC GO:0005887|GO:0015604|GO:0015716 VAPA_2c11630 f5b9d6e6b76d1e1c1b8f2370721e7f35 270 Gene3D G3DSA:1.10.3720.10 70 269 3.4E-32 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c08980 5afaa2946d672f2bc3fb40a8fae81cff 648 Pfam PF13193 AMP-binding enzyme C-terminal domain 493 568 3.6E-12 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain VAPA_1c08980 5afaa2946d672f2bc3fb40a8fae81cff 648 Gene3D G3DSA:3.40.50.12780 46 479 3.4E-84 T 12-10-2018 VAPA_1c08980 5afaa2946d672f2bc3fb40a8fae81cff 648 Gene3D G3DSA:3.30.300.30 480 585 5.6E-22 T 12-10-2018 VAPA_1c08980 5afaa2946d672f2bc3fb40a8fae81cff 648 ProSitePatterns PS00455 Putative AMP-binding domain signature. 227 238 - T 12-10-2018 IPR020845 AMP-binding, conserved site VAPA_1c08980 5afaa2946d672f2bc3fb40a8fae81cff 648 Pfam PF00501 AMP-binding enzyme 51 483 2.6E-71 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 VAPA_1c08980 5afaa2946d672f2bc3fb40a8fae81cff 648 SUPERFAMILY SSF56801 40 581 1.83E-114 T 12-10-2018 VAPA_1c52790 2794cc46424ed51a0f274c264218caf0 195 TIGRFAM TIGR00052 TIGR00052: nudix-type nucleoside diphosphatase, YffH/AdpP family 9 189 9.1E-39 T 12-10-2018 IPR004385 Nucleoside diphosphate pyrophosphatase GO:0016818|GO:0046872 Reactome: R-HSA-480985 VAPA_1c52790 2794cc46424ed51a0f274c264218caf0 195 Gene3D G3DSA:3.90.79.10 4 191 1.4E-46 T 12-10-2018 VAPA_1c52790 2794cc46424ed51a0f274c264218caf0 195 SUPERFAMILY SSF55811 8 191 3.36E-40 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 VAPA_1c52480 490952edeed87da095f2044de17b2a0b 131 Pfam PF00410 Ribosomal protein S8 5 130 1.1E-48 T 12-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VAPA_1c52480 490952edeed87da095f2044de17b2a0b 131 Gene3D G3DSA:3.30.1370.30 4 77 1.3E-28 T 12-10-2018 VAPA_1c52480 490952edeed87da095f2044de17b2a0b 131 Gene3D G3DSA:3.30.1490.10 78 131 1.4E-23 T 12-10-2018 VAPA_1c52480 490952edeed87da095f2044de17b2a0b 131 SUPERFAMILY SSF56047 2 130 5.23E-47 T 12-10-2018 IPR035987 Ribosomal protein S8 superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VAPA_1c52480 490952edeed87da095f2044de17b2a0b 131 Hamap MF_01302_B 30S ribosomal protein S8 [rpsH]. 2 131 31.983 T 12-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VAPA_1c52480 490952edeed87da095f2044de17b2a0b 131 ProSitePatterns PS00053 Ribosomal protein S8 signature. 101 118 - T 12-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VAPA_1c46700 381e0760be1e4c990f9e959b4d77d41d 341 Gene3D G3DSA:3.40.190.150 35 325 1.6E-70 T 12-10-2018 VAPA_1c46700 381e0760be1e4c990f9e959b4d77d41d 341 PIRSF PIRSF017082 1 339 6.5E-103 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c46700 381e0760be1e4c990f9e959b4d77d41d 341 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 68 334 3.7E-32 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c46700 381e0760be1e4c990f9e959b4d77d41d 341 Gene3D G3DSA:3.40.190.10 132 264 1.6E-70 T 12-10-2018 VAPA_2c12320 e499b889b7c052d50f3bc2e3e6e89ac8 314 Pfam PF02653 Branched-chain amino acid transport system / permease component 33 295 7.8E-41 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 VAPA_1c01890 ffc70d535d9780f14d4852b3a0ca3302 260 Pfam PF00005 ABC transporter 27 164 2.9E-31 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c01890 ffc70d535d9780f14d4852b3a0ca3302 260 SMART SM00382 34 213 9.1E-17 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c01890 ffc70d535d9780f14d4852b3a0ca3302 260 Gene3D G3DSA:3.40.50.300 3 255 5.0E-60 T 12-10-2018 VAPA_1c01890 ffc70d535d9780f14d4852b3a0ca3302 260 SUPERFAMILY SSF52540 5 236 6.44E-69 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c24070 34c1d9995e54f7892ebcd36cc0ff0807 695 Pfam PF13449 Esterase-like activity of phytase 261 625 9.8E-39 T 12-10-2018 IPR027372 Phytase-like domain VAPA_1c35600 c4433dc96e9464852549ce258a0aa7df 270 PIRSF PIRSF012318 4 270 1.6E-93 T 12-10-2018 IPR011197 Uncharacterised conserved protein UCP012318 VAPA_1c35600 c4433dc96e9464852549ce258a0aa7df 270 SUPERFAMILY SSF47240 52 233 7.69E-19 T 12-10-2018 IPR009078 Ferritin-like superfamily VAPA_1c35600 c4433dc96e9464852549ce258a0aa7df 270 Pfam PF04305 Protein of unknown function (DUF455) 14 261 2.1E-91 T 12-10-2018 IPR007402 Protein of unknown function DUF455 VAPA_1c18530 28905e6ab6ee9ee92588397588d5c44d 183 Pfam PF09361 Phasin protein 6 103 2.5E-28 T 12-10-2018 IPR018968 Phasin VAPA_1c18530 28905e6ab6ee9ee92588397588d5c44d 183 TIGRFAM TIGR01841 phasin: phasin family protein 26 108 3.1E-20 T 12-10-2018 IPR010127 Phasin, subfamily 1 VAPA_1c28470 7c8acc1b5965cc0597e63fe1025ebcfb 670 ProSitePatterns PS00211 ABC transporters family signature. 452 466 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_1c28470 7c8acc1b5965cc0597e63fe1025ebcfb 670 Gene3D G3DSA:3.40.50.300 5 283 5.4E-55 T 12-10-2018 VAPA_1c28470 7c8acc1b5965cc0597e63fe1025ebcfb 670 SMART SM00382 350 525 1.4E-9 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c28470 7c8acc1b5965cc0597e63fe1025ebcfb 670 SMART SM00382 26 233 2.9E-9 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c28470 7c8acc1b5965cc0597e63fe1025ebcfb 670 SUPERFAMILY SSF52540 308 537 7.59E-43 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c28470 7c8acc1b5965cc0597e63fe1025ebcfb 670 SUPERFAMILY SSF52540 2 250 2.95E-43 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c28470 7c8acc1b5965cc0597e63fe1025ebcfb 670 Pfam PF16326 ABC transporter C-terminal domain 604 662 9.2E-10 T 12-10-2018 IPR032524 ABC transporter Uup, C-terminal GO:0003677 VAPA_1c28470 7c8acc1b5965cc0597e63fe1025ebcfb 670 Pfam PF00005 ABC transporter 17 186 4.1E-21 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c28470 7c8acc1b5965cc0597e63fe1025ebcfb 670 ProSitePatterns PS00211 ABC transporters family signature. 158 172 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_1c28470 7c8acc1b5965cc0597e63fe1025ebcfb 670 Pfam PF00005 ABC transporter 341 480 2.6E-22 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c28470 7c8acc1b5965cc0597e63fe1025ebcfb 670 Pfam PF12848 ABC transporter 225 301 4.1E-28 T 12-10-2018 IPR032781 ABC-transporter extension domain VAPA_1c28470 7c8acc1b5965cc0597e63fe1025ebcfb 670 Gene3D G3DSA:3.40.50.300 284 560 2.0E-54 T 12-10-2018 VAPA_1c48480 ce9022007ed9fede2795a4ae67b90f6b 469 SUPERFAMILY SSF53383 113 461 2.48E-77 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase VAPA_1c48480 ce9022007ed9fede2795a4ae67b90f6b 469 Pfam PF00392 Bacterial regulatory proteins, gntR family 13 75 2.5E-12 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_1c48480 ce9022007ed9fede2795a4ae67b90f6b 469 Pfam PF00155 Aminotransferase class I and II 125 461 1.0E-35 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 VAPA_1c48480 ce9022007ed9fede2795a4ae67b90f6b 469 SMART SM00345 16 75 1.4E-11 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_1c48480 ce9022007ed9fede2795a4ae67b90f6b 469 Gene3D G3DSA:3.40.640.10 146 362 1.3E-74 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 VAPA_1c48480 ce9022007ed9fede2795a4ae67b90f6b 469 Gene3D G3DSA:3.90.1150.10 130 455 1.3E-74 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 VAPA_1c48480 ce9022007ed9fede2795a4ae67b90f6b 469 SUPERFAMILY SSF46785 5 78 8.59E-18 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c48480 ce9022007ed9fede2795a4ae67b90f6b 469 Gene3D G3DSA:1.10.10.10 2 84 1.6E-17 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c14160 967a6ef5d89f123e5e461a5bb8c30781 250 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 189 0.0021 T 12-10-2018 VAPA_1c14160 967a6ef5d89f123e5e461a5bb8c30781 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 1.3E-6 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c14160 967a6ef5d89f123e5e461a5bb8c30781 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 1.3E-6 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c14160 967a6ef5d89f123e5e461a5bb8c30781 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 1.3E-6 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c14160 967a6ef5d89f123e5e461a5bb8c30781 250 SUPERFAMILY SSF51735 4 228 6.08E-58 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c14160 967a6ef5d89f123e5e461a5bb8c30781 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 2.4E-17 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c14160 967a6ef5d89f123e5e461a5bb8c30781 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 2.4E-17 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c14160 967a6ef5d89f123e5e461a5bb8c30781 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 2.4E-17 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c14160 967a6ef5d89f123e5e461a5bb8c30781 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 2.4E-17 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c14160 967a6ef5d89f123e5e461a5bb8c30781 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 2.4E-17 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c14160 967a6ef5d89f123e5e461a5bb8c30781 250 Gene3D G3DSA:3.40.50.720 1 241 2.9E-60 T 12-10-2018 VAPA_1c14160 967a6ef5d89f123e5e461a5bb8c30781 250 Pfam PF00106 short chain dehydrogenase 7 188 5.3E-44 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c39960 17b25dd1af76d5932071c6265af22e6f 295 Pfam PF04228 Putative neutral zinc metallopeptidase 1 290 1.1E-119 T 12-10-2018 IPR007343 Uncharacterised protein family, zinc metallopeptidase putative VAPA_2c01330 b104fb47851735e3a5db57d37779caf8 134 Gene3D G3DSA:3.10.450.50 2 125 1.5E-34 T 12-10-2018 VAPA_2c01330 b104fb47851735e3a5db57d37779caf8 134 SUPERFAMILY SSF54427 10 130 1.2E-29 T 12-10-2018 IPR032710 NTF2-like domain superfamily VAPA_2c01330 b104fb47851735e3a5db57d37779caf8 134 Pfam PF12680 SnoaL-like domain 14 116 2.6E-25 T 12-10-2018 IPR037401 SnoaL-like domain VAPA_1c27390 1e31ca92a3292611a530a269b8bd2d90 330 SUPERFAMILY SSF46689 210 261 2.76E-11 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 VAPA_1c27390 1e31ca92a3292611a530a269b8bd2d90 330 SUPERFAMILY SSF46689 263 313 2.46E-7 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 VAPA_1c27390 1e31ca92a3292611a530a269b8bd2d90 330 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 264 306 - T 12-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 VAPA_1c27390 1e31ca92a3292611a530a269b8bd2d90 330 Gene3D G3DSA:1.10.10.60 210 313 3.6E-25 T 12-10-2018 VAPA_1c27390 1e31ca92a3292611a530a269b8bd2d90 330 SMART SM00342 227 310 5.9E-23 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 VAPA_1c27390 1e31ca92a3292611a530a269b8bd2d90 330 Pfam PF06719 AraC-type transcriptional regulator N-terminus 48 198 4.6E-42 T 12-10-2018 IPR009594 Transcription regulator HTH, AraC, N-terminal VAPA_1c27390 1e31ca92a3292611a530a269b8bd2d90 330 Pfam PF12833 Helix-turn-helix domain 233 308 1.7E-19 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 VAPA_1c17750 12f52947a129a7114b7293fd572f0e16 115 PIRSF PIRSF028139 3 115 1.0E-39 T 12-10-2018 IPR014980 Dopa 4,5-dioxygenase VAPA_1c17750 12f52947a129a7114b7293fd572f0e16 115 SUPERFAMILY SSF143410 2 113 8.76E-40 T 12-10-2018 IPR023389 DOPA-like superfamily VAPA_1c17750 12f52947a129a7114b7293fd572f0e16 115 Gene3D G3DSA:3.30.70.1240 4 115 3.3E-35 T 12-10-2018 IPR023389 DOPA-like superfamily VAPA_1c17750 12f52947a129a7114b7293fd572f0e16 115 Pfam PF08883 Dopa 4,5-dioxygenase family 12 111 2.4E-30 T 12-10-2018 IPR014980 Dopa 4,5-dioxygenase VAPA_1c03420 dc661b724ec2c0258c0aedd28298bdb2 228 Pfam PF13511 Domain of unknown function (DUF4124) 34 90 2.7E-5 T 12-10-2018 IPR025392 Domain of unknown function DUF4124 VAPA_1c00870 280f1200cbfa2e27c8082997c0f5c1c8 324 Pfam PF02653 Branched-chain amino acid transport system / permease component 36 304 1.1E-41 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 VAPA_1c30920 a055e1c55d917e75f08cf1cfecc999bb 358 SUPERFAMILY SSF56655 6 335 1.19E-107 T 12-10-2018 VAPA_1c30920 a055e1c55d917e75f08cf1cfecc999bb 358 PIRSF PIRSF500210 4 340 4.3E-126 T 12-10-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 VAPA_1c30920 a055e1c55d917e75f08cf1cfecc999bb 358 ProSitePatterns PS00124 Fructose-1-6-bisphosphatase active site. 277 289 - T 12-10-2018 IPR020548 Fructose-1,6-bisphosphatase, active site GO:0005975|GO:0042578 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 VAPA_1c30920 a055e1c55d917e75f08cf1cfecc999bb 358 Hamap MF_01855 Fructose-1,6-bisphosphatase class 1 [fbp]. 7 337 45.287 T 12-10-2018 IPR000146 Fructose-1,6-bisphosphatase class 1 GO:0005975|GO:0016791 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 VAPA_1c30920 a055e1c55d917e75f08cf1cfecc999bb 358 Gene3D G3DSA:3.30.540.10 4 200 1.5E-71 T 12-10-2018 VAPA_1c30920 a055e1c55d917e75f08cf1cfecc999bb 358 Pfam PF00316 Fructose-1-6-bisphosphatase, N-terminal domain 8 197 5.4E-61 T 12-10-2018 IPR033391 Fructose-1-6-bisphosphatase class I, N-terminal KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 VAPA_1c30920 a055e1c55d917e75f08cf1cfecc999bb 358 Gene3D G3DSA:3.40.190.80 201 341 3.3E-48 T 12-10-2018 VAPA_1c30920 a055e1c55d917e75f08cf1cfecc999bb 358 PIRSF PIRSF000904 4 341 2.2E-122 T 12-10-2018 IPR000146 Fructose-1,6-bisphosphatase class 1 GO:0005975|GO:0016791 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 VAPA_1c30920 a055e1c55d917e75f08cf1cfecc999bb 358 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 311 336 8.0E-68 T 12-10-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 VAPA_1c30920 a055e1c55d917e75f08cf1cfecc999bb 358 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 69 95 8.0E-68 T 12-10-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 VAPA_1c30920 a055e1c55d917e75f08cf1cfecc999bb 358 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 32 59 8.0E-68 T 12-10-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 VAPA_1c30920 a055e1c55d917e75f08cf1cfecc999bb 358 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 183 206 8.0E-68 T 12-10-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 VAPA_1c30920 a055e1c55d917e75f08cf1cfecc999bb 358 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 152 175 8.0E-68 T 12-10-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 VAPA_1c30920 a055e1c55d917e75f08cf1cfecc999bb 358 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 209 236 8.0E-68 T 12-10-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 VAPA_1c31550 4b438642eefa19f990b1d84853d41735 325 SUPERFAMILY SSF82829 236 317 2.88E-18 T 12-10-2018 VAPA_1c31550 4b438642eefa19f990b1d84853d41735 325 Pfam PF09179 TilS substrate binding domain 247 308 6.0E-13 T 12-10-2018 IPR015262 tRNA(Ile)-lysidine synthase , substrate-binding domain GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 VAPA_1c31550 4b438642eefa19f990b1d84853d41735 325 Pfam PF01171 PP-loop family 20 199 6.5E-50 T 12-10-2018 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 VAPA_1c31550 4b438642eefa19f990b1d84853d41735 325 Gene3D G3DSA:1.20.59.20 234 314 1.0E-8 T 12-10-2018 VAPA_1c31550 4b438642eefa19f990b1d84853d41735 325 Gene3D G3DSA:3.40.50.620 13 233 2.6E-69 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold VAPA_1c31550 4b438642eefa19f990b1d84853d41735 325 SUPERFAMILY SSF52402 19 232 1.54E-57 T 12-10-2018 VAPA_1c31550 4b438642eefa19f990b1d84853d41735 325 Hamap MF_01161 tRNA(Ile)-lysidine synthase [tilS]. 5 307 22.852 T 12-10-2018 IPR012094 tRNA(Ile)-lysidine synthase GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 VAPA_1c31550 4b438642eefa19f990b1d84853d41735 325 TIGRFAM TIGR02432 lysidine_TilS_N: tRNA(Ile)-lysidine synthetase 19 203 7.9E-48 T 12-10-2018 IPR012795 tRNA(Ile)-lysidine synthase, N-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 VAPA_1c40640 e261539f6855f8021e7ac1e30a15fc09 433 SUPERFAMILY SSF53383 19 425 3.43E-44 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase VAPA_1c40640 e261539f6855f8021e7ac1e30a15fc09 433 Gene3D G3DSA:3.40.640.10 46 301 9.7E-50 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 VAPA_1c40640 e261539f6855f8021e7ac1e30a15fc09 433 Gene3D G3DSA:3.90.1150.10 38 420 9.7E-50 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 VAPA_1c40640 e261539f6855f8021e7ac1e30a15fc09 433 Pfam PF00266 Aminotransferase class-V 39 411 6.3E-24 T 12-10-2018 IPR000192 Aminotransferase class V domain VAPA_1c47940 0b96509f816bdc50612d51132ea72298 220 Pfam PF13532 2OG-Fe(II) oxygenase superfamily 38 217 6.6E-53 T 12-10-2018 IPR027450 Alpha-ketoglutarate-dependent dioxygenase AlkB-like VAPA_1c47940 0b96509f816bdc50612d51132ea72298 220 SUPERFAMILY SSF51197 22 218 2.33E-59 T 12-10-2018 VAPA_1c47940 0b96509f816bdc50612d51132ea72298 220 Gene3D G3DSA:2.60.120.590 19 220 5.3E-57 T 12-10-2018 IPR037151 Alpha-ketoglutarate-dependent dioxygenase AlkB-like superfamily VAPA_1c45950 f6ebcfb3fe1364526e8a9a023eb74a98 536 Pfam PF06956 Regulator of RNA terminal phosphate cyclase 3 183 1.0E-82 T 12-10-2018 IPR009715 Regulator of RNA terminal phosphate cyclase VAPA_1c45950 f6ebcfb3fe1364526e8a9a023eb74a98 536 Gene3D G3DSA:1.10.8.60 360 441 8.4E-6 T 12-10-2018 VAPA_1c45950 f6ebcfb3fe1364526e8a9a023eb74a98 536 Gene3D G3DSA:3.40.50.300 171 359 7.6E-50 T 12-10-2018 VAPA_1c45950 f6ebcfb3fe1364526e8a9a023eb74a98 536 SMART SM00382 205 351 8.3E-12 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c45950 f6ebcfb3fe1364526e8a9a023eb74a98 536 SUPERFAMILY SSF52540 187 434 1.53E-49 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c45950 f6ebcfb3fe1364526e8a9a023eb74a98 536 PIRSF PIRSF037354 1 535 6.0E-257 T 12-10-2018 IPR017183 Sigma54-dependent transcriptional activator, RtcR GO:0003700|GO:0006355 VAPA_1c45950 f6ebcfb3fe1364526e8a9a023eb74a98 536 Pfam PF00158 Sigma-54 interaction domain 186 351 6.1E-50 T 12-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 VAPA_1c39380 c0cde0e3870673a0e447e5093f16bc09 278 SUPERFAMILY SSF55781 97 265 7.19E-48 T 12-10-2018 VAPA_1c39380 c0cde0e3870673a0e447e5093f16bc09 278 Pfam PF09339 IclR helix-turn-helix domain 26 75 1.1E-11 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 VAPA_1c39380 c0cde0e3870673a0e447e5093f16bc09 278 SMART SM00346 27 112 5.8E-7 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 VAPA_1c39380 c0cde0e3870673a0e447e5093f16bc09 278 Pfam PF01614 Bacterial transcriptional regulator 140 265 3.4E-30 T 12-10-2018 IPR014757 Transcription regulator IclR, C-terminal VAPA_1c39380 c0cde0e3870673a0e447e5093f16bc09 278 SUPERFAMILY SSF46785 26 91 1.74E-12 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c39380 c0cde0e3870673a0e447e5093f16bc09 278 Gene3D G3DSA:3.30.450.40 97 269 1.9E-52 T 12-10-2018 IPR029016 GAF-like domain superfamily VAPA_1c39380 c0cde0e3870673a0e447e5093f16bc09 278 Gene3D G3DSA:1.10.10.10 25 94 1.5E-14 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c25830 5dcb93b9df23653fa8d124ecf81675f7 455 Gene3D G3DSA:3.50.50.60 17 415 7.9E-119 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c25830 5dcb93b9df23653fa8d124ecf81675f7 455 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 22 44 1.1E-8 T 12-10-2018 VAPA_1c25830 5dcb93b9df23653fa8d124ecf81675f7 455 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 170 185 1.1E-8 T 12-10-2018 VAPA_1c25830 5dcb93b9df23653fa8d124ecf81675f7 455 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 301 316 1.1E-8 T 12-10-2018 VAPA_1c25830 5dcb93b9df23653fa8d124ecf81675f7 455 Pfam PF01494 FAD binding domain 21 340 3.0E-20 T 12-10-2018 IPR002938 FAD-binding domain GO:0071949 VAPA_1c25830 5dcb93b9df23653fa8d124ecf81675f7 455 SUPERFAMILY SSF51905 21 384 4.45E-44 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c02310 81947f91188664129dc91d116115463b 288 Pfam PF07024 ImpE protein 159 278 6.0E-37 T 12-10-2018 IPR009211 Predicted virulence protein, SciE type VAPA_1c02310 81947f91188664129dc91d116115463b 288 Gene3D G3DSA:1.25.40.10 5 87 3.6E-16 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 VAPA_1c02310 81947f91188664129dc91d116115463b 288 SUPERFAMILY SSF144059 8 282 1.96E-62 T 12-10-2018 VAPA_1c02310 81947f91188664129dc91d116115463b 288 PIRSF PIRSF029288 3 285 5.4E-65 T 12-10-2018 IPR009211 Predicted virulence protein, SciE type VAPA_1c12260 b7914df9388ef761dd0f11eb582f9351 363 Gene3D G3DSA:3.90.1150.10 24 356 3.0E-107 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 VAPA_1c12260 b7914df9388ef761dd0f11eb582f9351 363 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 13 363 53.587 T 12-10-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 VAPA_1c12260 b7914df9388ef761dd0f11eb582f9351 363 Gene3D G3DSA:3.40.640.10 53 268 3.0E-107 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 VAPA_1c12260 b7914df9388ef761dd0f11eb582f9351 363 TIGRFAM TIGR01141 hisC: histidinol-phosphate transaminase 15 360 2.1E-93 T 12-10-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 VAPA_1c12260 b7914df9388ef761dd0f11eb582f9351 363 SUPERFAMILY SSF53383 18 361 1.65E-69 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase VAPA_1c12260 b7914df9388ef761dd0f11eb582f9351 363 Pfam PF00155 Aminotransferase class I and II 70 357 8.2E-42 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 VAPA_2c08860 d05fb0c5e062d7d59695ef8930c01b55 467 ProSitePatterns PS00571 Amidases signature. 160 191 - T 12-10-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 VAPA_2c08860 d05fb0c5e062d7d59695ef8930c01b55 467 Pfam PF01425 Amidase 34 442 2.1E-93 T 12-10-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 VAPA_2c08860 d05fb0c5e062d7d59695ef8930c01b55 467 SUPERFAMILY SSF75304 19 451 9.16E-112 T 12-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 VAPA_2c08860 d05fb0c5e062d7d59695ef8930c01b55 467 Gene3D G3DSA:3.90.1300.10 17 452 1.4E-123 T 12-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 VAPA_2c04990 044a0ed120065f6e359e9e0d079fbffe 353 Gene3D G3DSA:2.40.50.100 53 193 7.4E-60 T 12-10-2018 VAPA_2c04990 044a0ed120065f6e359e9e0d079fbffe 353 Gene3D G3DSA:2.40.30.170 41 275 7.4E-60 T 12-10-2018 VAPA_2c04990 044a0ed120065f6e359e9e0d079fbffe 353 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 32 345 2.9E-56 T 12-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 VAPA_2c04990 044a0ed120065f6e359e9e0d079fbffe 353 Gene3D G3DSA:2.40.420.20 39 338 7.4E-60 T 12-10-2018 VAPA_2c04990 044a0ed120065f6e359e9e0d079fbffe 353 SUPERFAMILY SSF111369 44 274 3.79E-26 T 12-10-2018 VAPA_2c04990 044a0ed120065f6e359e9e0d079fbffe 353 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 52 269 6.3E-19 T 12-10-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain VAPA_2c04990 044a0ed120065f6e359e9e0d079fbffe 353 Gene3D G3DSA:1.10.287.470 87 158 7.4E-60 T 12-10-2018 VAPA_1c37950 8ead2cebbc7b8b9a98e3d48d29c009a2 344 Gene3D G3DSA:3.20.20.190 30 336 1.0E-100 T 12-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 VAPA_1c37950 8ead2cebbc7b8b9a98e3d48d29c009a2 344 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 45 323 1.2E-44 T 12-10-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 VAPA_1c37950 8ead2cebbc7b8b9a98e3d48d29c009a2 344 SUPERFAMILY SSF51695 40 328 2.12E-64 T 12-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 VAPA_2c12410 9fe8cd534ca7888379a57cc08146316c 333 Gene3D G3DSA:3.90.180.10 8 330 1.6E-107 T 12-10-2018 VAPA_2c12410 9fe8cd534ca7888379a57cc08146316c 333 SMART SM00829 10 330 1.3E-43 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 VAPA_2c12410 9fe8cd534ca7888379a57cc08146316c 333 SUPERFAMILY SSF51735 117 297 2.93E-39 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_2c12410 9fe8cd534ca7888379a57cc08146316c 333 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 89 2.5E-12 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 VAPA_2c12410 9fe8cd534ca7888379a57cc08146316c 333 SUPERFAMILY SSF50129 1 150 3.04E-40 T 12-10-2018 IPR011032 GroES-like superfamily VAPA_2c12410 9fe8cd534ca7888379a57cc08146316c 333 Gene3D G3DSA:3.40.50.720 125 301 1.6E-107 T 12-10-2018 VAPA_2c12410 9fe8cd534ca7888379a57cc08146316c 333 Pfam PF13602 Zinc-binding dehydrogenase 187 330 2.0E-35 T 12-10-2018 VAPA_2c01290 4171ec4a8b9f2ecfc601f2a04ff16aca 382 Gene3D G3DSA:1.10.230.10 248 335 4.9E-38 T 12-10-2018 IPR016143 Citrate synthase-like, small alpha subdomain VAPA_2c01290 4171ec4a8b9f2ecfc601f2a04ff16aca 382 Gene3D G3DSA:1.10.580.10 185 361 4.9E-38 T 12-10-2018 IPR016142 Citrate synthase-like, large alpha subdomain Reactome: R-HSA-1268020|Reactome: R-HSA-71403 VAPA_2c01290 4171ec4a8b9f2ecfc601f2a04ff16aca 382 PRINTS PR00143 Citrate synthase signature 222 250 1.7E-15 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 VAPA_2c01290 4171ec4a8b9f2ecfc601f2a04ff16aca 382 PRINTS PR00143 Citrate synthase signature 200 215 1.7E-15 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 VAPA_2c01290 4171ec4a8b9f2ecfc601f2a04ff16aca 382 PRINTS PR00143 Citrate synthase signature 274 294 1.7E-15 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 VAPA_2c01290 4171ec4a8b9f2ecfc601f2a04ff16aca 382 Pfam PF00285 Citrate synthase, C-terminal domain 178 371 1.8E-43 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 VAPA_2c01290 4171ec4a8b9f2ecfc601f2a04ff16aca 382 SUPERFAMILY SSF48256 28 380 2.88E-63 T 12-10-2018 IPR036969 Citrate synthase superfamily GO:0046912 VAPA_2c01290 4171ec4a8b9f2ecfc601f2a04ff16aca 382 Pfam PF12728 Helix-turn-helix domain 4 50 1.5E-6 T 12-10-2018 VAPA_1c43490 b6f6ae8ee45f3c93fc9d973677970c40 371 Hamap MF_00416 Flagellar P-ring protein [flgI]. 9 371 37.419 T 12-10-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 VAPA_1c43490 b6f6ae8ee45f3c93fc9d973677970c40 371 PRINTS PR01010 Flagellar P-ring protein signature 169 187 5.3E-84 T 12-10-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 VAPA_1c43490 b6f6ae8ee45f3c93fc9d973677970c40 371 PRINTS PR01010 Flagellar P-ring protein signature 44 59 5.3E-84 T 12-10-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 VAPA_1c43490 b6f6ae8ee45f3c93fc9d973677970c40 371 PRINTS PR01010 Flagellar P-ring protein signature 29 44 5.3E-84 T 12-10-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 VAPA_1c43490 b6f6ae8ee45f3c93fc9d973677970c40 371 PRINTS PR01010 Flagellar P-ring protein signature 90 109 5.3E-84 T 12-10-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 VAPA_1c43490 b6f6ae8ee45f3c93fc9d973677970c40 371 PRINTS PR01010 Flagellar P-ring protein signature 112 129 5.3E-84 T 12-10-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 VAPA_1c43490 b6f6ae8ee45f3c93fc9d973677970c40 371 PRINTS PR01010 Flagellar P-ring protein signature 129 147 5.3E-84 T 12-10-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 VAPA_1c43490 b6f6ae8ee45f3c93fc9d973677970c40 371 PRINTS PR01010 Flagellar P-ring protein signature 195 213 5.3E-84 T 12-10-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 VAPA_1c43490 b6f6ae8ee45f3c93fc9d973677970c40 371 PRINTS PR01010 Flagellar P-ring protein signature 258 270 5.3E-84 T 12-10-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 VAPA_1c43490 b6f6ae8ee45f3c93fc9d973677970c40 371 PRINTS PR01010 Flagellar P-ring protein signature 64 79 5.3E-84 T 12-10-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 VAPA_1c43490 b6f6ae8ee45f3c93fc9d973677970c40 371 Pfam PF02119 Flagellar P-ring protein 29 370 1.3E-138 T 12-10-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 VAPA_1c21350 bdd23d0fa688d3229bf104f76f0bcf3a 551 SUPERFAMILY SSF56024 64 259 3.4E-38 T 12-10-2018 VAPA_1c21350 bdd23d0fa688d3229bf104f76f0bcf3a 551 Gene3D G3DSA:3.30.870.10 88 266 2.4E-35 T 12-10-2018 VAPA_1c21350 bdd23d0fa688d3229bf104f76f0bcf3a 551 SUPERFAMILY SSF56024 342 489 1.46E-26 T 12-10-2018 VAPA_1c21350 bdd23d0fa688d3229bf104f76f0bcf3a 551 SMART SM00155 189 216 0.0074 T 12-10-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 VAPA_1c21350 bdd23d0fa688d3229bf104f76f0bcf3a 551 SMART SM00155 440 467 5.4E-5 T 12-10-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 VAPA_1c21350 bdd23d0fa688d3229bf104f76f0bcf3a 551 Pfam PF13091 PLD-like domain 351 489 6.5E-18 T 12-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 VAPA_1c21350 bdd23d0fa688d3229bf104f76f0bcf3a 551 Pfam PF13091 PLD-like domain 96 248 1.2E-15 T 12-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 VAPA_1c21350 bdd23d0fa688d3229bf104f76f0bcf3a 551 Gene3D G3DSA:3.30.870.10 335 495 7.1E-32 T 12-10-2018 VAPA_2c13220 b0b071abfe5a0d55d6dad7aa33e6b5ea 651 SUPERFAMILY SSF52540 87 541 6.9E-52 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_2c13220 b0b071abfe5a0d55d6dad7aa33e6b5ea 651 Gene3D G3DSA:3.40.50.300 304 540 7.3E-43 T 12-10-2018 VAPA_2c13220 b0b071abfe5a0d55d6dad7aa33e6b5ea 651 Pfam PF02534 Type IV secretory system Conjugative DNA transfer 101 545 3.4E-106 T 12-10-2018 IPR003688 Type IV secretion system protein TraG/VirD4 GO:0009291|GO:0016020 VAPA_1c04360 929b9fdaa117c2573ff9a6331f1cbf5e 202 Gene3D G3DSA:3.40.30.10 4 194 1.9E-67 T 12-10-2018 VAPA_1c04360 929b9fdaa117c2573ff9a6331f1cbf5e 202 Gene3D G3DSA:1.20.1050.10 82 192 1.9E-67 T 12-10-2018 VAPA_1c04360 929b9fdaa117c2573ff9a6331f1cbf5e 202 Pfam PF13417 Glutathione S-transferase, N-terminal domain 5 80 1.3E-17 T 12-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 VAPA_1c04360 929b9fdaa117c2573ff9a6331f1cbf5e 202 SUPERFAMILY SSF47616 73 200 2.76E-13 T 12-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily VAPA_1c04360 929b9fdaa117c2573ff9a6331f1cbf5e 202 SUPERFAMILY SSF52833 1 77 9.16E-16 T 12-10-2018 IPR036249 Thioredoxin-like superfamily VAPA_1c16840 939ee7a1049f3fbc552e76600d75e8e4 239 SUPERFAMILY SSF52540 16 226 1.86E-55 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c16840 939ee7a1049f3fbc552e76600d75e8e4 239 Pfam PF00005 ABC transporter 30 164 1.2E-27 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c16840 939ee7a1049f3fbc552e76600d75e8e4 239 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_1c16840 939ee7a1049f3fbc552e76600d75e8e4 239 Gene3D G3DSA:3.40.50.300 14 236 9.5E-57 T 12-10-2018 VAPA_1c16840 939ee7a1049f3fbc552e76600d75e8e4 239 SMART SM00382 39 211 2.1E-14 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_2c01360 d5c5e300274442ff6dff1c5cf685ce90 330 TIGRFAM TIGR00787 dctP: TRAP transporter solute receptor, DctP family 37 290 3.1E-73 T 12-10-2018 IPR004682 TRAP transporter solute receptor, DctP family GO:0030288|GO:0055085 VAPA_2c01360 d5c5e300274442ff6dff1c5cf685ce90 330 PIRSF PIRSF006470 5 330 6.9E-99 T 12-10-2018 IPR004682 TRAP transporter solute receptor, DctP family GO:0030288|GO:0055085 VAPA_2c01360 d5c5e300274442ff6dff1c5cf685ce90 330 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 36 316 8.8E-88 T 12-10-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0030288|GO:0055085 VAPA_2c01360 d5c5e300274442ff6dff1c5cf685ce90 330 Gene3D G3DSA:3.40.190.170 28 330 4.5E-111 T 12-10-2018 IPR038404 TRAP transporter solute receptor DctP superfamily VAPA_1c47870 98f83bb433f30834cf82b6a9b81d3040 378 Gene3D G3DSA:3.50.50.60 127 323 4.8E-47 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c47870 98f83bb433f30834cf82b6a9b81d3040 378 Pfam PF01494 FAD binding domain 126 326 2.1E-14 T 12-10-2018 IPR002938 FAD-binding domain GO:0071949 VAPA_1c47870 98f83bb433f30834cf82b6a9b81d3040 378 ProSitePatterns PS01304 ubiH/COQ6 monooxygenase family signature. 280 293 - T 12-10-2018 IPR018168 Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6, conserved site GO:0016709|GO:0055114 Reactome: R-HSA-2142789 VAPA_1c47870 98f83bb433f30834cf82b6a9b81d3040 378 Gene3D G3DSA:3.30.9.50 157 245 4.8E-47 T 12-10-2018 VAPA_1c47870 98f83bb433f30834cf82b6a9b81d3040 378 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 266 281 5.2E-11 T 12-10-2018 VAPA_1c47870 98f83bb433f30834cf82b6a9b81d3040 378 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 281 297 5.2E-11 T 12-10-2018 VAPA_1c47870 98f83bb433f30834cf82b6a9b81d3040 378 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 6 28 5.2E-11 T 12-10-2018 VAPA_1c47870 98f83bb433f30834cf82b6a9b81d3040 378 SUPERFAMILY SSF51905 5 369 5.37E-38 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c47870 98f83bb433f30834cf82b6a9b81d3040 378 Gene3D G3DSA:3.50.50.60 5 125 3.5E-22 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c26510 879834a307d2bee1b3256dab77ed949a 179 SUPERFAMILY SSF53155 5 83 8.24E-13 T 12-10-2018 IPR036631 Methylated DNA-protein cysteine methyltransferase domain superfamily GO:0003908|GO:0006281 Reactome: R-HSA-5657655 VAPA_1c26510 879834a307d2bee1b3256dab77ed949a 179 Gene3D G3DSA:1.10.10.10 85 171 2.5E-26 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c26510 879834a307d2bee1b3256dab77ed949a 179 SUPERFAMILY SSF46767 87 169 3.27E-24 T 12-10-2018 IPR036217 Methylated DNA-protein cysteine methyltransferase, DNA binding domain Reactome: R-HSA-5657655 VAPA_1c26510 879834a307d2bee1b3256dab77ed949a 179 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 137 143 - T 12-10-2018 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 Reactome: R-HSA-5657655 VAPA_1c26510 879834a307d2bee1b3256dab77ed949a 179 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 88 168 2.6E-20 T 12-10-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 VAPA_1c26510 879834a307d2bee1b3256dab77ed949a 179 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 88 169 1.7E-28 T 12-10-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 VAPA_1c12290 f73f7300b787781000caae00770f21f3 247 SUPERFAMILY SSF51366 1 238 3.06E-73 T 12-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 VAPA_1c12290 f73f7300b787781000caae00770f21f3 247 Hamap MF_01014 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase [hisA]. 2 240 36.078 T 12-10-2018 IPR023016 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16 VAPA_1c12290 f73f7300b787781000caae00770f21f3 247 Gene3D G3DSA:3.20.20.70 1 242 5.6E-86 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 VAPA_1c12290 f73f7300b787781000caae00770f21f3 247 TIGRFAM TIGR00007 TIGR00007: 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase 3 235 1.2E-77 T 12-10-2018 IPR006063 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase HisA GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16 VAPA_1c12290 f73f7300b787781000caae00770f21f3 247 Pfam PF00977 Histidine biosynthesis protein 3 232 1.6E-79 T 12-10-2018 IPR006062 Histidine biosynthesis GO:0000105 VAPA_1c24950 2d0f650b75ee40968fc10b0da6b818e7 122 Gene3D G3DSA:3.10.450.50 1 114 5.8E-16 T 12-10-2018 VAPA_1c24950 2d0f650b75ee40968fc10b0da6b818e7 122 SUPERFAMILY SSF54427 1 118 5.61E-18 T 12-10-2018 IPR032710 NTF2-like domain superfamily VAPA_1c24950 2d0f650b75ee40968fc10b0da6b818e7 122 Pfam PF12680 SnoaL-like domain 8 109 1.5E-9 T 12-10-2018 IPR037401 SnoaL-like domain VAPA_1c44110 9cda6c1edc3c7751e552da37cd487b35 385 Pfam PF13609 Gram-negative porin 7 345 2.2E-64 T 12-10-2018 VAPA_1c44110 9cda6c1edc3c7751e552da37cd487b35 385 SUPERFAMILY SSF56935 20 385 4.58E-65 T 12-10-2018 VAPA_1c44110 9cda6c1edc3c7751e552da37cd487b35 385 PRINTS PR00184 Neisseria sp. porin signature 99 118 8.3E-10 T 12-10-2018 IPR002299 Porin, Neisseria sp. type GO:0015288|GO:0016020|GO:0055085 VAPA_1c44110 9cda6c1edc3c7751e552da37cd487b35 385 PRINTS PR00184 Neisseria sp. porin signature 316 340 8.3E-10 T 12-10-2018 IPR002299 Porin, Neisseria sp. type GO:0015288|GO:0016020|GO:0055085 VAPA_1c44110 9cda6c1edc3c7751e552da37cd487b35 385 PRINTS PR00184 Neisseria sp. porin signature 61 86 8.3E-10 T 12-10-2018 IPR002299 Porin, Neisseria sp. type GO:0015288|GO:0016020|GO:0055085 VAPA_1c44110 9cda6c1edc3c7751e552da37cd487b35 385 Gene3D G3DSA:2.40.160.10 20 385 1.1E-81 T 12-10-2018 IPR023614 Porin domain superfamily VAPA_1c32020 76a66d64ca5a1ff846a2b8e86607d8c7 239 Gene3D G3DSA:1.10.10.10 159 238 2.1E-16 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c32020 76a66d64ca5a1ff846a2b8e86607d8c7 239 Pfam PF00027 Cyclic nucleotide-binding domain 41 129 2.6E-19 T 12-10-2018 IPR000595 Cyclic nucleotide-binding domain VAPA_1c32020 76a66d64ca5a1ff846a2b8e86607d8c7 239 SUPERFAMILY SSF51206 16 154 1.31E-28 T 12-10-2018 IPR018490 Cyclic nucleotide-binding-like VAPA_1c32020 76a66d64ca5a1ff846a2b8e86607d8c7 239 SUPERFAMILY SSF46785 159 236 1.04E-14 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c32020 76a66d64ca5a1ff846a2b8e86607d8c7 239 SMART SM00100 21 145 1.6E-14 T 12-10-2018 IPR000595 Cyclic nucleotide-binding domain VAPA_1c32020 76a66d64ca5a1ff846a2b8e86607d8c7 239 SMART SM00419 180 228 4.5E-7 T 12-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 VAPA_1c32020 76a66d64ca5a1ff846a2b8e86607d8c7 239 Pfam PF13545 Crp-like helix-turn-helix domain 162 235 3.7E-15 T 12-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 VAPA_1c32020 76a66d64ca5a1ff846a2b8e86607d8c7 239 Gene3D G3DSA:2.60.120.10 7 158 2.5E-33 T 12-10-2018 IPR014710 RmlC-like jelly roll fold VAPA_1c48930 6c73310839faab6e70f55bc1ac7d512c 628 Gene3D G3DSA:3.20.20.540 208 521 5.4E-152 T 12-10-2018 IPR038521 ThiC/Bza superfamily KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 VAPA_1c48930 6c73310839faab6e70f55bc1ac7d512c 628 Hamap MF_00089 Phosphomethylpyrimidine synthase [thiC]. 133 590 99.075 T 12-10-2018 IPR037509 Phosphomethylpyrimidine synthase GO:0009228|GO:0016830 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 VAPA_1c48930 6c73310839faab6e70f55bc1ac7d512c 628 TIGRFAM TIGR00190 thiC: phosphomethylpyrimidine synthase 133 588 2.6E-212 T 12-10-2018 IPR002817 Phosphomethylpyrimidine synthase ThiC/5-hydroxybenzimidazole synthase BzaA/B GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 VAPA_1c48930 6c73310839faab6e70f55bc1ac7d512c 628 Pfam PF13667 ThiC-associated domain 17 85 1.7E-21 T 12-10-2018 IPR025747 ThiC-associated domain KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 VAPA_1c48930 6c73310839faab6e70f55bc1ac7d512c 628 Pfam PF01964 Radical SAM ThiC family 134 586 2.3E-199 T 12-10-2018 IPR002817 Phosphomethylpyrimidine synthase ThiC/5-hydroxybenzimidazole synthase BzaA/B GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 VAPA_1c35290 5745bd2282609a6a2e48e139e6295b0e 530 Gene3D G3DSA:3.40.50.1820 117 302 1.9E-12 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c35290 5745bd2282609a6a2e48e139e6295b0e 530 SUPERFAMILY SSF53474 136 252 7.91E-11 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c15000 21c9b2119fde26c142daf4c8ea50126e 367 Gene3D G3DSA:3.20.20.300 3 361 7.1E-110 T 12-10-2018 IPR036962 Glycoside hydrolase, family 3, N-terminal domain superfamily GO:0004553|GO:0005975 VAPA_1c15000 21c9b2119fde26c142daf4c8ea50126e 367 SUPERFAMILY SSF51445 11 311 2.74E-73 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily VAPA_1c15000 21c9b2119fde26c142daf4c8ea50126e 367 Hamap MF_00364 Beta-hexosaminidase [nagZ]. 11 361 48.067 T 12-10-2018 IPR022956 Beta-hexosaminidase, bacterial GO:0004563 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|MetaCyc: PWY-7883 VAPA_1c15000 21c9b2119fde26c142daf4c8ea50126e 367 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 15 296 6.5E-68 T 12-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 VAPA_1c20540 b4dcedb274d988d72ee38e977ec05417 217 Gene3D G3DSA:3.40.50.850 8 203 3.9E-47 T 12-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 VAPA_1c20540 b4dcedb274d988d72ee38e977ec05417 217 Pfam PF00857 Isochorismatase family 16 166 3.0E-24 T 12-10-2018 IPR000868 Isochorismatase-like GO:0003824 VAPA_1c20540 b4dcedb274d988d72ee38e977ec05417 217 SUPERFAMILY SSF52499 8 204 5.36E-48 T 12-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 VAPA_1c12080 c9802cff2e666657c88d369b1d38975c 191 Pfam PF07209 Protein of unknown function (DUF1415) 13 180 3.5E-63 T 12-10-2018 IPR009858 Protein of unknown function DUF1415 VAPA_1c38730 40cf539e622f67fca1026d09873a7337 229 Gene3D G3DSA:3.90.470.20 120 223 2.5E-24 T 12-10-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 VAPA_1c38730 40cf539e622f67fca1026d09873a7337 229 SUPERFAMILY SSF56214 120 225 3.53E-16 T 12-10-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 VAPA_1c38730 40cf539e622f67fca1026d09873a7337 229 SUPERFAMILY SSF56214 30 108 1.74E-15 T 12-10-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 VAPA_1c38730 40cf539e622f67fca1026d09873a7337 229 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 120 198 4.3E-13 T 12-10-2018 IPR008278 4'-phosphopantetheinyl transferase domain GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 VAPA_1c38730 40cf539e622f67fca1026d09873a7337 229 Gene3D G3DSA:3.90.470.20 32 119 2.5E-24 T 12-10-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 VAPA_1c27840 8c359c94a37d3fe8bc5713a188450a3b 239 SUPERFAMILY SSF55186 90 233 1.06E-26 T 12-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 VAPA_1c27840 8c359c94a37d3fe8bc5713a188450a3b 239 SUPERFAMILY SSF50447 1 72 4.24E-7 T 12-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily VAPA_1c27840 8c359c94a37d3fe8bc5713a188450a3b 239 Gene3D G3DSA:3.30.980.10 86 237 1.5E-26 T 12-10-2018 VAPA_1c27840 8c359c94a37d3fe8bc5713a188450a3b 239 SMART SM00863 190 233 4.7E-11 T 12-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 VAPA_1c27840 8c359c94a37d3fe8bc5713a188450a3b 239 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 190 232 3.5E-8 T 12-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 VAPA_1c27840 8c359c94a37d3fe8bc5713a188450a3b 239 Gene3D G3DSA:2.40.30.130 1 85 1.2E-9 T 12-10-2018 VAPA_1c26610 bb20256de9b74fd6fc5bf8a25e461260 236 Pfam PF04403 Paraquat-inducible protein A 58 213 8.9E-51 T 12-10-2018 IPR007498 Intermembrane transport protein PqiA-like VAPA_1c39840 2b8921150952f511a41d00640200d1ae 254 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_1c39840 2b8921150952f511a41d00640200d1ae 254 SMART SM00382 36 230 8.1E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c39840 2b8921150952f511a41d00640200d1ae 254 Pfam PF00005 ABC transporter 27 165 8.7E-33 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c39840 2b8921150952f511a41d00640200d1ae 254 SUPERFAMILY SSF52540 8 239 3.78E-69 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c39840 2b8921150952f511a41d00640200d1ae 254 Gene3D G3DSA:3.40.50.300 6 244 6.2E-63 T 12-10-2018 VAPA_1c48020 33878a84f28c212f811ff05f13acc57d 200 Gene3D G3DSA:1.20.120.1760 8 200 2.2E-23 T 12-10-2018 VAPA_1c48020 33878a84f28c212f811ff05f13acc57d 200 Pfam PF01066 CDP-alcohol phosphatidyltransferase 27 95 2.0E-9 T 12-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 VAPA_1c24470 910ba15926513b825f4d075877d909d4 153 PIRSF PIRSF000709 3 75 0.0018 T 12-10-2018 VAPA_1c24470 910ba15926513b825f4d075877d909d4 153 Gene3D G3DSA:3.40.50.1240 1 149 6.4E-30 T 12-10-2018 IPR029033 Histidine phosphatase superfamily VAPA_1c24470 910ba15926513b825f4d075877d909d4 153 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 3 77 1.4E-10 T 12-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 VAPA_1c24470 910ba15926513b825f4d075877d909d4 153 SMART SM00855 2 109 3.6E-8 T 12-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 VAPA_1c24470 910ba15926513b825f4d075877d909d4 153 SUPERFAMILY SSF53254 3 143 6.58E-23 T 12-10-2018 IPR029033 Histidine phosphatase superfamily VAPA_1c40090 d9d1e269cb17e514b4b9075fa2b52713 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 47 58 5.6E-7 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c40090 d9d1e269cb17e514b4b9075fa2b52713 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 37 47 5.6E-7 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c40090 d9d1e269cb17e514b4b9075fa2b52713 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 26 37 5.6E-7 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c40090 d9d1e269cb17e514b4b9075fa2b52713 300 Gene3D G3DSA:1.10.10.10 2 91 3.3E-31 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c40090 d9d1e269cb17e514b4b9075fa2b52713 300 Gene3D G3DSA:3.40.190.10 174 269 2.6E-46 T 12-10-2018 VAPA_1c40090 d9d1e269cb17e514b4b9075fa2b52713 300 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 11 69 2.1E-17 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c40090 d9d1e269cb17e514b4b9075fa2b52713 300 Pfam PF03466 LysR substrate binding domain 100 297 1.3E-13 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_1c40090 d9d1e269cb17e514b4b9075fa2b52713 300 Gene3D G3DSA:3.40.190.10 95 292 2.6E-46 T 12-10-2018 VAPA_1c40090 d9d1e269cb17e514b4b9075fa2b52713 300 SUPERFAMILY SSF53850 93 295 2.17E-28 T 12-10-2018 VAPA_1c40090 d9d1e269cb17e514b4b9075fa2b52713 300 SUPERFAMILY SSF46785 7 88 3.27E-20 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c03350 5f73b846c7ce6f575e82a7de91b4369f 223 Pfam PF00857 Isochorismatase family 18 206 4.3E-42 T 12-10-2018 IPR000868 Isochorismatase-like GO:0003824 VAPA_1c03350 5f73b846c7ce6f575e82a7de91b4369f 223 SUPERFAMILY SSF52499 5 210 5.1E-53 T 12-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 VAPA_1c03350 5f73b846c7ce6f575e82a7de91b4369f 223 Gene3D G3DSA:3.40.50.850 9 223 6.4E-55 T 12-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 VAPA_1c25820 e2b7e150beaf157b29053fcc1f7a7d19 304 PIRSF PIRSF000441 120 297 1.8E-52 T 12-10-2018 IPR005881 Serine O-acetyltransferase GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|KEGG: 00999+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274|MetaCyc: PWY-7870 VAPA_1c25820 e2b7e150beaf157b29053fcc1f7a7d19 304 SUPERFAMILY SSF51161 101 290 5.11E-45 T 12-10-2018 IPR011004 Trimeric LpxA-like superfamily VAPA_1c25820 e2b7e150beaf157b29053fcc1f7a7d19 304 Gene3D G3DSA:1.10.3130.10 33 187 5.7E-47 T 12-10-2018 VAPA_1c25820 e2b7e150beaf157b29053fcc1f7a7d19 304 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 247 281 1.8E-6 T 12-10-2018 IPR001451 Hexapeptide repeat VAPA_1c25820 e2b7e150beaf157b29053fcc1f7a7d19 304 Gene3D G3DSA:2.160.10.10 188 300 3.1E-30 T 12-10-2018 VAPA_1c23080 ffdcbf8de65e904dd6fba970c61bb6f3 471 Pfam PF06850 PHB de-polymerase C-terminus 212 418 4.2E-89 T 12-10-2018 IPR009656 PHB de-polymerase, C-terminal VAPA_1c23080 ffdcbf8de65e904dd6fba970c61bb6f3 471 SUPERFAMILY SSF53474 105 415 5.33E-31 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c23080 ffdcbf8de65e904dd6fba970c61bb6f3 471 PIRSF PIRSF020818 1 430 2.7E-184 T 12-10-2018 IPR010915 Polyhydroxyalkanoate depolymerase VAPA_1c23080 ffdcbf8de65e904dd6fba970c61bb6f3 471 TIGRFAM TIGR01849 PHB_depoly_PhaZ: polyhydroxyalkanoate depolymerase, intracellular 2 417 9.2E-172 T 12-10-2018 IPR010915 Polyhydroxyalkanoate depolymerase VAPA_1c02600 f6829e0ebe8f33e7a29f9c137c4d0dd3 328 SUPERFAMILY SSF63825 84 275 1.15E-5 T 12-10-2018 VAPA_1c10330 59509c16e74827f6b7c4940067563526 131 ProDom PD031420 YFEK EXPORTED PRECURSOR SIGNAL PERIPLASMIC ECS3291 XCC0326 28 113 2.0E-11 T 12-10-2018 IPR035242 Protein of unknown function DUF5329 VAPA_1c10330 59509c16e74827f6b7c4940067563526 131 Pfam PF17263 Family of unknown function (DUF5329) 30 122 5.7E-29 T 12-10-2018 IPR035242 Protein of unknown function DUF5329 VAPA_1c28280 fc457fcf20e941ef7fad09eb16684e2b 147 Gene3D G3DSA:3.40.50.10110 5 142 1.3E-30 T 12-10-2018 IPR036768 DNA polymerase III subunit chi superfamily VAPA_1c28280 fc457fcf20e941ef7fad09eb16684e2b 147 Pfam PF04364 DNA polymerase III chi subunit, HolC 2 137 7.2E-32 T 12-10-2018 IPR007459 DNA polymerase III chi subunit, HolC GO:0003677|GO:0003887|GO:0006260 VAPA_1c28280 fc457fcf20e941ef7fad09eb16684e2b 147 SUPERFAMILY SSF102400 2 141 1.26E-29 T 12-10-2018 IPR036768 DNA polymerase III subunit chi superfamily VAPA_1c30940 a8953a34cf0c6dcad4d0793f72c26415 234 TIGRFAM TIGR01163 rpe: ribulose-phosphate 3-epimerase 10 219 7.5E-93 T 12-10-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 VAPA_1c30940 a8953a34cf0c6dcad4d0793f72c26415 234 ProSitePatterns PS01085 Ribulose-phosphate 3-epimerase family signature 1. 37 51 - T 12-10-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 VAPA_1c30940 a8953a34cf0c6dcad4d0793f72c26415 234 ProSitePatterns PS01086 Ribulose-phosphate 3-epimerase family signature 2. 139 161 - T 12-10-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 VAPA_1c30940 a8953a34cf0c6dcad4d0793f72c26415 234 SUPERFAMILY SSF51366 5 221 1.02E-72 T 12-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 VAPA_1c30940 a8953a34cf0c6dcad4d0793f72c26415 234 PIRSF PIRSF001461 4 230 1.2E-100 T 12-10-2018 IPR026019 Ribulose-phosphate 3-epimerase GO:0004750|GO:0006098 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 VAPA_1c30940 a8953a34cf0c6dcad4d0793f72c26415 234 Gene3D G3DSA:3.20.20.70 1 220 2.4E-81 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 VAPA_1c30940 a8953a34cf0c6dcad4d0793f72c26415 234 Pfam PF00834 Ribulose-phosphate 3 epimerase family 10 206 1.1E-90 T 12-10-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 VAPA_1c37550 d9ce38a46d9a165277e2763fa787652a 518 SUPERFAMILY SSF55931 13 495 1.44E-174 T 12-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 VAPA_1c37550 d9ce38a46d9a165277e2763fa787652a 518 Gene3D G3DSA:3.30.590.20 15 507 2.5E-174 T 12-10-2018 VAPA_1c37550 d9ce38a46d9a165277e2763fa787652a 518 Pfam PF04262 Glutamate-cysteine ligase 158 361 9.3E-77 T 12-10-2018 IPR007370 Glutamate--cysteine ligase GO:0004357|GO:0006750 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 VAPA_1c37550 d9ce38a46d9a165277e2763fa787652a 518 Hamap MF_00578 Glutamate--cysteine ligase [gshA]. 1 518 197.333 T 12-10-2018 IPR006334 Glutamate--cysteine ligase, monofunctional GO:0004357|GO:0006750 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 VAPA_1c37550 d9ce38a46d9a165277e2763fa787652a 518 TIGRFAM TIGR01434 glu_cys_ligase: glutamate--cysteine ligase 16 498 4.1E-149 T 12-10-2018 IPR006334 Glutamate--cysteine ligase, monofunctional GO:0004357|GO:0006750 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 VAPA_1c37460 0fa63e6661b8fbd8ca75544b53eaec37 149 SUPERFAMILY SSF46785 3 134 6.65E-20 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c37460 0fa63e6661b8fbd8ca75544b53eaec37 149 Gene3D G3DSA:3.30.1490.190 88 141 3.2E-6 T 12-10-2018 VAPA_1c37460 0fa63e6661b8fbd8ca75544b53eaec37 149 Pfam PF01475 Ferric uptake regulator family 3 79 7.2E-12 T 12-10-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 VAPA_1c37460 0fa63e6661b8fbd8ca75544b53eaec37 149 Gene3D G3DSA:1.10.10.10 1 71 1.6E-14 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c35820 42a78ad51bbae4111bd852fbf6f228c4 123 SUPERFAMILY SSF54909 1 114 1.22E-33 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel VAPA_1c35820 42a78ad51bbae4111bd852fbf6f228c4 123 Pfam PF03795 YCII-related domain 1 114 2.4E-21 T 12-10-2018 IPR005545 YCII-related VAPA_1c35820 42a78ad51bbae4111bd852fbf6f228c4 123 Gene3D G3DSA:3.30.70.1060 1 117 1.2E-38 T 12-10-2018 VAPA_1c07520 1327d1b0821053c42c48f73cdf9ab796 88 Pfam PF13560 Helix-turn-helix domain 13 67 6.5E-12 T 12-10-2018 VAPA_1c07520 1327d1b0821053c42c48f73cdf9ab796 88 SUPERFAMILY SSF47413 11 69 1.45E-13 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 VAPA_1c07520 1327d1b0821053c42c48f73cdf9ab796 88 SMART SM00530 16 71 3.7E-10 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 VAPA_1c07520 1327d1b0821053c42c48f73cdf9ab796 88 Gene3D G3DSA:1.10.260.40 1 78 1.0E-24 T 12-10-2018 VAPA_1c21690 16b11b51daec5ae52f9ca25a9a49a397 357 SUPERFAMILY SSF46894 217 271 5.78E-16 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 VAPA_1c21690 16b11b51daec5ae52f9ca25a9a49a397 357 SMART SM00421 221 276 9.5E-11 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_1c21690 16b11b51daec5ae52f9ca25a9a49a397 357 Pfam PF00196 Bacterial regulatory proteins, luxR family 223 271 1.1E-13 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_1c21690 16b11b51daec5ae52f9ca25a9a49a397 357 ProSitePatterns PS00622 LuxR-type HTH domain signature. 238 265 - T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_1c21690 16b11b51daec5ae52f9ca25a9a49a397 357 Gene3D G3DSA:3.40.50.12740 87 277 6.2E-21 T 12-10-2018 VAPA_1c21690 16b11b51daec5ae52f9ca25a9a49a397 357 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 254 266 2.4E-8 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_1c21690 16b11b51daec5ae52f9ca25a9a49a397 357 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 238 254 2.4E-8 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_1c21690 16b11b51daec5ae52f9ca25a9a49a397 357 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 224 238 2.4E-8 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_1c53810 a5cba4aaede67deb6bf3843b1f6b965e 410 Gene3D G3DSA:3.40.50.2000 223 393 1.8E-16 T 12-10-2018 VAPA_1c53810 a5cba4aaede67deb6bf3843b1f6b965e 410 Pfam PF13692 Glycosyl transferases group 1 232 371 4.3E-11 T 12-10-2018 VAPA_1c53810 a5cba4aaede67deb6bf3843b1f6b965e 410 Gene3D G3DSA:3.40.50.2000 1 213 3.4E-24 T 12-10-2018 VAPA_1c53810 a5cba4aaede67deb6bf3843b1f6b965e 410 SUPERFAMILY SSF53756 2 406 1.67E-43 T 12-10-2018 VAPA_1c53810 a5cba4aaede67deb6bf3843b1f6b965e 410 Pfam PF13579 Glycosyl transferase 4-like domain 16 201 5.6E-22 T 12-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 VAPA_1c08120 bdf7b78b0aa6024e7c920bf8eaaa5db3 426 Pfam PF10442 FIST C domain 236 409 9.1E-31 T 12-10-2018 IPR019494 FIST, C-domain Reactome: R-HSA-8951664|Reactome: R-HSA-983168 VAPA_1c08120 bdf7b78b0aa6024e7c920bf8eaaa5db3 426 SMART SM00897 37 235 1.5E-34 T 12-10-2018 IPR013702 FIST domain, N-terminal VAPA_1c08120 bdf7b78b0aa6024e7c920bf8eaaa5db3 426 SMART SM01204 236 410 1.1E-29 T 12-10-2018 IPR019494 FIST, C-domain Reactome: R-HSA-8951664|Reactome: R-HSA-983168 VAPA_1c08120 bdf7b78b0aa6024e7c920bf8eaaa5db3 426 Pfam PF08495 FIST N domain 40 234 1.7E-21 T 12-10-2018 IPR013702 FIST domain, N-terminal VAPA_1c30050 0d5bc082c685d919e61983d34f144940 647 Gene3D G3DSA:2.170.130.10 49 176 6.2E-35 T 12-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily VAPA_1c30050 0d5bc082c685d919e61983d34f144940 647 Pfam PF00593 TonB dependent receptor 240 645 4.8E-35 T 12-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel VAPA_1c30050 0d5bc082c685d919e61983d34f144940 647 Gene3D G3DSA:2.40.170.20 178 645 7.7E-105 T 12-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily VAPA_1c30050 0d5bc082c685d919e61983d34f144940 647 Pfam PF07715 TonB-dependent Receptor Plug Domain 66 171 4.7E-28 T 12-10-2018 IPR012910 TonB-dependent receptor, plug domain VAPA_1c30050 0d5bc082c685d919e61983d34f144940 647 SUPERFAMILY SSF56935 53 644 1.34E-112 T 12-10-2018 VAPA_2c01000 5c37b9e9c6672d4e78f5da41deb924aa 501 Gene3D G3DSA:2.120.10.30 57 267 3.1E-5 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like VAPA_2c01000 5c37b9e9c6672d4e78f5da41deb924aa 501 Gene3D G3DSA:2.60.120.380 398 500 1.7E-24 T 12-10-2018 VAPA_2c01000 5c37b9e9c6672d4e78f5da41deb924aa 501 SUPERFAMILY SSF63829 88 323 1.18E-6 T 12-10-2018 VAPA_1c41030 e23bcde5008667cb766b902a24c7bceb 285 Pfam PF00005 ABC transporter 35 180 3.8E-30 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c41030 e23bcde5008667cb766b902a24c7bceb 285 SMART SM00382 43 230 1.4E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c41030 e23bcde5008667cb766b902a24c7bceb 285 ProSitePatterns PS00211 ABC transporters family signature. 153 167 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_1c41030 e23bcde5008667cb766b902a24c7bceb 285 SUPERFAMILY SSF52540 13 250 4.31E-61 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c41030 e23bcde5008667cb766b902a24c7bceb 285 Gene3D G3DSA:3.40.50.300 11 264 3.2E-56 T 12-10-2018 VAPA_1c22020 7764f76fc937fcfa187d1707866b0fef 259 Gene3D G3DSA:2.40.400.10 2 258 2.7E-57 T 12-10-2018 IPR023375 Acetoacetate decarboxylase domain superfamily KEGG: 00072+4.1.1.4|KEGG: 00640+4.1.1.4|MetaCyc: PWY-5451|MetaCyc: PWY-6588|MetaCyc: PWY-6876|MetaCyc: PWY-7466 VAPA_1c22020 7764f76fc937fcfa187d1707866b0fef 259 SUPERFAMILY SSF160104 15 254 1.7E-24 T 12-10-2018 IPR023375 Acetoacetate decarboxylase domain superfamily KEGG: 00072+4.1.1.4|KEGG: 00640+4.1.1.4|MetaCyc: PWY-5451|MetaCyc: PWY-6588|MetaCyc: PWY-6876|MetaCyc: PWY-7466 VAPA_1c22020 7764f76fc937fcfa187d1707866b0fef 259 Pfam PF06314 Acetoacetate decarboxylase (ADC) 8 254 3.7E-30 T 12-10-2018 IPR010451 Acetoacetate decarboxylase GO:0016829 KEGG: 00072+4.1.1.4|KEGG: 00640+4.1.1.4|MetaCyc: PWY-5451|MetaCyc: PWY-6588|MetaCyc: PWY-6876|MetaCyc: PWY-7466 VAPA_1c33770 cbf72b698b6c70a90f6eb5ad0a3421f4 391 Gene3D G3DSA:3.40.50.10540 4 374 3.6E-128 T 12-10-2018 IPR023606 CoA-transferase family III domain superfamily VAPA_1c33770 cbf72b698b6c70a90f6eb5ad0a3421f4 391 Gene3D G3DSA:3.30.1540.10 226 324 3.6E-128 T 12-10-2018 VAPA_1c33770 cbf72b698b6c70a90f6eb5ad0a3421f4 391 Pfam PF02515 CoA-transferase family III 4 372 1.3E-126 T 12-10-2018 IPR003673 CoA-transferase family III GO:0003824 VAPA_1c33770 cbf72b698b6c70a90f6eb5ad0a3421f4 391 SUPERFAMILY SSF89796 1 375 1.31E-127 T 12-10-2018 IPR023606 CoA-transferase family III domain superfamily VAPA_1c08500 0757c246bbc096c9c5ad716cefc27a91 248 SUPERFAMILY SSF51735 4 247 1.14E-76 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c08500 0757c246bbc096c9c5ad716cefc27a91 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 2.5E-39 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c08500 0757c246bbc096c9c5ad716cefc27a91 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 2.5E-39 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c08500 0757c246bbc096c9c5ad716cefc27a91 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 2.5E-39 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c08500 0757c246bbc096c9c5ad716cefc27a91 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 2.5E-39 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c08500 0757c246bbc096c9c5ad716cefc27a91 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 2.5E-39 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c08500 0757c246bbc096c9c5ad716cefc27a91 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 209 229 2.5E-39 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c08500 0757c246bbc096c9c5ad716cefc27a91 248 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 244 1.0E-58 T 12-10-2018 VAPA_1c08500 0757c246bbc096c9c5ad716cefc27a91 248 Gene3D G3DSA:3.40.50.720 2 247 1.5E-79 T 12-10-2018 VAPA_1c08500 0757c246bbc096c9c5ad716cefc27a91 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 2.4E-14 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c08500 0757c246bbc096c9c5ad716cefc27a91 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 2.4E-14 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c08500 0757c246bbc096c9c5ad716cefc27a91 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 2.4E-14 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c08500 0757c246bbc096c9c5ad716cefc27a91 248 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 142 170 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 VAPA_1c01360 dc228cacd2070224d8d5c2a0e959cf59 120 Gene3D G3DSA:2.60.120.10 3 119 6.7E-11 T 12-10-2018 IPR014710 RmlC-like jelly roll fold VAPA_1c01360 dc228cacd2070224d8d5c2a0e959cf59 120 SUPERFAMILY SSF51182 2 115 2.51E-11 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily VAPA_1c55100 af25923c7c7db1d6ccc94fdcd10dba37 563 TIGRFAM TIGR03592 yidC_oxa1_cterm: membrane protein insertase, YidC/Oxa1 family 377 556 2.4E-66 T 12-10-2018 IPR028055 Membrane insertase YidC/Oxa1, C-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 VAPA_1c55100 af25923c7c7db1d6ccc94fdcd10dba37 563 PRINTS PR00701 60kDa inner membrane protein signature 89 110 1.5E-69 T 12-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 VAPA_1c55100 af25923c7c7db1d6ccc94fdcd10dba37 563 PRINTS PR00701 60kDa inner membrane protein signature 3 24 1.5E-69 T 12-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 VAPA_1c55100 af25923c7c7db1d6ccc94fdcd10dba37 563 PRINTS PR00701 60kDa inner membrane protein signature 181 201 1.5E-69 T 12-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 VAPA_1c55100 af25923c7c7db1d6ccc94fdcd10dba37 563 PRINTS PR00701 60kDa inner membrane protein signature 348 368 1.5E-69 T 12-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 VAPA_1c55100 af25923c7c7db1d6ccc94fdcd10dba37 563 PRINTS PR00701 60kDa inner membrane protein signature 486 508 1.5E-69 T 12-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 VAPA_1c55100 af25923c7c7db1d6ccc94fdcd10dba37 563 PRINTS PR00701 60kDa inner membrane protein signature 270 285 1.5E-69 T 12-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 VAPA_1c55100 af25923c7c7db1d6ccc94fdcd10dba37 563 PRINTS PR00701 60kDa inner membrane protein signature 439 462 1.5E-69 T 12-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 VAPA_1c55100 af25923c7c7db1d6ccc94fdcd10dba37 563 PRINTS PR00701 60kDa inner membrane protein signature 522 545 1.5E-69 T 12-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 VAPA_1c55100 af25923c7c7db1d6ccc94fdcd10dba37 563 PRINTS PR00701 60kDa inner membrane protein signature 235 253 1.5E-69 T 12-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 VAPA_1c55100 af25923c7c7db1d6ccc94fdcd10dba37 563 PRINTS PR01900 YidC translocation/secretion protein signature 363 379 3.8E-20 T 12-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 VAPA_1c55100 af25923c7c7db1d6ccc94fdcd10dba37 563 PRINTS PR01900 YidC translocation/secretion protein signature 492 507 3.8E-20 T 12-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 VAPA_1c55100 af25923c7c7db1d6ccc94fdcd10dba37 563 PRINTS PR01900 YidC translocation/secretion protein signature 511 535 3.8E-20 T 12-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 VAPA_1c55100 af25923c7c7db1d6ccc94fdcd10dba37 563 TIGRFAM TIGR03593 yidC_nterm: membrane protein insertase, YidC/Oxa1 family, N-terminal domain 4 376 6.9E-97 T 12-10-2018 IPR028053 Membrane insertase YidC, N-terminal VAPA_1c55100 af25923c7c7db1d6ccc94fdcd10dba37 563 Pfam PF02096 60Kd inner membrane protein 378 556 1.9E-57 T 12-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 VAPA_1c55100 af25923c7c7db1d6ccc94fdcd10dba37 563 Pfam PF14849 YidC periplasmic domain 83 367 2.5E-71 T 12-10-2018 IPR038210 Membrane insertase YidC, periplasmic domain VAPA_1c55100 af25923c7c7db1d6ccc94fdcd10dba37 563 Gene3D G3DSA:2.70.98.90 80 357 5.0E-73 T 12-10-2018 IPR038221 YidC, periplasmic domain superfamily VAPA_1c55100 af25923c7c7db1d6ccc94fdcd10dba37 563 Hamap MF_01810 Membrane protein insertase YidC [yidC]. 5 558 22.586 T 12-10-2018 IPR019998 Membrane insertase YidC GO:0016021|GO:0032977 VAPA_1c41050 5763e9e61f05066bd22f236db25e47e7 160 Gene3D G3DSA:3.40.140.10 2 155 1.2E-26 T 12-10-2018 VAPA_1c41050 5763e9e61f05066bd22f236db25e47e7 160 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 8 100 7.8E-14 T 12-10-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain VAPA_1c41050 5763e9e61f05066bd22f236db25e47e7 160 SUPERFAMILY SSF53927 4 157 5.02E-31 T 12-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 VAPA_1c38180 ea84c38a5adb70101676d37ae63f30f2 236 SUPERFAMILY SSF51735 1 215 9.7E-47 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c38180 ea84c38a5adb70101676d37ae63f30f2 236 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 130 158 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 VAPA_1c38180 ea84c38a5adb70101676d37ae63f30f2 236 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 164 181 3.0E-20 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c38180 ea84c38a5adb70101676d37ae63f30f2 236 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 3.0E-20 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c38180 ea84c38a5adb70101676d37ae63f30f2 236 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 143 162 3.0E-20 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c38180 ea84c38a5adb70101676d37ae63f30f2 236 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 69 80 3.0E-20 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c38180 ea84c38a5adb70101676d37ae63f30f2 236 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 117 133 3.0E-20 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c38180 ea84c38a5adb70101676d37ae63f30f2 236 Gene3D G3DSA:3.40.50.720 1 230 2.1E-45 T 12-10-2018 VAPA_1c38180 ea84c38a5adb70101676d37ae63f30f2 236 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 69 80 2.4E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c38180 ea84c38a5adb70101676d37ae63f30f2 236 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 143 162 2.4E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c38180 ea84c38a5adb70101676d37ae63f30f2 236 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 123 131 2.4E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c38180 ea84c38a5adb70101676d37ae63f30f2 236 Pfam PF00106 short chain dehydrogenase 7 183 4.4E-33 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c47760 d1ead29f1b9286f53a9358c34001e175 156 Pfam PF09335 SNARE associated Golgi protein 52 145 1.6E-10 T 12-10-2018 IPR032816 SNARE associated Golgi protein VAPA_1c47760 d1ead29f1b9286f53a9358c34001e175 156 ProDom PD085709 MEMBRANE RP436 UNCHARACTERIZED INTEGRAL PREDICTED TRANSMEMBRANE 20 135 2.0E-4 T 12-10-2018 IPR020143 Uncharacterised protein family, RP436 VAPA_2c07300 9605155944121dd104ad3efedfa4749d 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 72 83 9.2E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c07300 9605155944121dd104ad3efedfa4749d 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 145 164 9.2E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c07300 9605155944121dd104ad3efedfa4749d 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 125 133 9.2E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c07300 9605155944121dd104ad3efedfa4749d 250 SUPERFAMILY SSF51735 7 221 6.06E-60 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_2c07300 9605155944121dd104ad3efedfa4749d 250 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 181 0.0064 T 12-10-2018 VAPA_2c07300 9605155944121dd104ad3efedfa4749d 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 166 183 3.8E-28 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c07300 9605155944121dd104ad3efedfa4749d 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 145 164 3.8E-28 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c07300 9605155944121dd104ad3efedfa4749d 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 72 83 3.8E-28 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c07300 9605155944121dd104ad3efedfa4749d 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 119 135 3.8E-28 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c07300 9605155944121dd104ad3efedfa4749d 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 3.8E-28 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c07300 9605155944121dd104ad3efedfa4749d 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 199 219 3.8E-28 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c07300 9605155944121dd104ad3efedfa4749d 250 Pfam PF00106 short chain dehydrogenase 7 186 7.5E-46 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c07300 9605155944121dd104ad3efedfa4749d 250 Gene3D G3DSA:3.40.50.720 4 241 1.9E-59 T 12-10-2018 VAPA_1c45160 1cf762afbb2cea84f398beb0162e85eb 223 ProDom PD012503 RIBOSOMAL L25 50S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN STRESS GENERAL CTC RRNA 1 93 1.0E-41 T 12-10-2018 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 VAPA_1c45160 1cf762afbb2cea84f398beb0162e85eb 223 Pfam PF14693 Ribosomal protein TL5, C-terminal domain 99 185 2.4E-28 T 12-10-2018 IPR020057 Ribosomal protein L25, beta domain VAPA_1c45160 1cf762afbb2cea84f398beb0162e85eb 223 Gene3D G3DSA:2.40.240.10 1 93 1.3E-29 T 12-10-2018 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, N-terminal Reactome: R-HSA-2408517|Reactome: R-HSA-379716 VAPA_1c45160 1cf762afbb2cea84f398beb0162e85eb 223 SUPERFAMILY SSF50715 2 191 1.07E-51 T 12-10-2018 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain superfamily GO:0006412 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 VAPA_1c45160 1cf762afbb2cea84f398beb0162e85eb 223 Gene3D G3DSA:2.170.120.20 96 193 6.8E-25 T 12-10-2018 IPR037121 Ribosomal protein L25, C-terminal VAPA_1c45160 1cf762afbb2cea84f398beb0162e85eb 223 TIGRFAM TIGR00731 bL25_bact_ctc: ribosomal protein bL25, Ctc-form 6 176 6.8E-44 T 12-10-2018 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 VAPA_1c45160 1cf762afbb2cea84f398beb0162e85eb 223 Hamap MF_01334 50S ribosomal protein L25 [rplY]. 1 184 29.502 T 12-10-2018 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 VAPA_1c45160 1cf762afbb2cea84f398beb0162e85eb 223 Pfam PF01386 Ribosomal L25p family 6 90 1.2E-21 T 12-10-2018 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 VAPA_1c25620 261d28d807f2f1a775955a00493da18f 342 Pfam PF00248 Aldo/keto reductase family 16 319 5.6E-67 T 12-10-2018 IPR023210 NADP-dependent oxidoreductase domain VAPA_1c25620 261d28d807f2f1a775955a00493da18f 342 PRINTS PR00069 Aldo-keto reductase signature 113 131 2.6E-6 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 VAPA_1c25620 261d28d807f2f1a775955a00493da18f 342 PRINTS PR00069 Aldo-keto reductase signature 48 72 2.6E-6 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 VAPA_1c25620 261d28d807f2f1a775955a00493da18f 342 PRINTS PR00069 Aldo-keto reductase signature 144 161 2.6E-6 T 12-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 VAPA_1c25620 261d28d807f2f1a775955a00493da18f 342 Gene3D G3DSA:3.20.20.100 1 340 5.2E-133 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily VAPA_1c25620 261d28d807f2f1a775955a00493da18f 342 SUPERFAMILY SSF51430 1 322 7.07E-99 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily VAPA_1c33150 55a86f7cffc8cdaacdc1abe7078fe081 332 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 56 329 1.4E-80 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c33150 55a86f7cffc8cdaacdc1abe7078fe081 332 SUPERFAMILY SSF53850 132 294 5.27E-10 T 12-10-2018 VAPA_1c33150 55a86f7cffc8cdaacdc1abe7078fe081 332 PIRSF PIRSF017082 4 332 5.2E-76 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c33150 55a86f7cffc8cdaacdc1abe7078fe081 332 Gene3D G3DSA:3.40.190.150 38 322 1.1E-103 T 12-10-2018 VAPA_1c33150 55a86f7cffc8cdaacdc1abe7078fe081 332 Gene3D G3DSA:3.40.190.10 134 257 1.1E-103 T 12-10-2018 VAPA_1c15810 f5f5345491ad8e41c9ef12336cafe2bd 158 SUPERFAMILY SSF46785 12 147 6.92E-32 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c15810 f5f5345491ad8e41c9ef12336cafe2bd 158 PRINTS PR00598 Bacterial regulatory protein MarR family signature 93 109 2.6E-8 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 VAPA_1c15810 f5f5345491ad8e41c9ef12336cafe2bd 158 PRINTS PR00598 Bacterial regulatory protein MarR family signature 74 89 2.6E-8 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 VAPA_1c15810 f5f5345491ad8e41c9ef12336cafe2bd 158 PRINTS PR00598 Bacterial regulatory protein MarR family signature 57 73 2.6E-8 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 VAPA_1c15810 f5f5345491ad8e41c9ef12336cafe2bd 158 Gene3D G3DSA:1.10.10.10 2 147 3.0E-34 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c15810 f5f5345491ad8e41c9ef12336cafe2bd 158 Pfam PF01047 MarR family 41 97 5.9E-14 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 VAPA_1c15810 f5f5345491ad8e41c9ef12336cafe2bd 158 SMART SM00347 33 133 1.5E-18 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 VAPA_1c40960 21356625057ea544ebf58a3cfc81386f 444 SUPERFAMILY SSF51905 11 389 1.04E-41 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c40960 21356625057ea544ebf58a3cfc81386f 444 Gene3D G3DSA:3.50.50.60 8 404 7.3E-117 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c40960 21356625057ea544ebf58a3cfc81386f 444 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 165 180 8.1E-8 T 12-10-2018 VAPA_1c40960 21356625057ea544ebf58a3cfc81386f 444 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 295 310 8.1E-8 T 12-10-2018 VAPA_1c40960 21356625057ea544ebf58a3cfc81386f 444 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 12 34 8.1E-8 T 12-10-2018 VAPA_1c40960 21356625057ea544ebf58a3cfc81386f 444 Pfam PF04820 Tryptophan halogenase 101 323 1.3E-19 T 12-10-2018 IPR006905 Flavin-dependent halogenase VAPA_1c40960 21356625057ea544ebf58a3cfc81386f 444 Pfam PF04820 Tryptophan halogenase 12 96 4.5E-12 T 12-10-2018 IPR006905 Flavin-dependent halogenase VAPA_1c11970 c9102861ef4d90bf0556025cef040dce 110 TIGRFAM TIGR03421 FeS_CyaY: iron donor protein CyaY 2 107 7.5E-36 T 12-10-2018 IPR002908 Frataxin/CyaY GO:0008199|GO:0016226 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 VAPA_1c11970 c9102861ef4d90bf0556025cef040dce 110 Gene3D G3DSA:3.30.920.10 1 109 4.6E-36 T 12-10-2018 IPR036524 Frataxin/CyaY superfamily GO:0008199|GO:0016226 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 VAPA_1c11970 c9102861ef4d90bf0556025cef040dce 110 ProSitePatterns PS01344 Frataxin family signature. 52 66 - T 12-10-2018 IPR020895 Frataxin conserved site Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 VAPA_1c11970 c9102861ef4d90bf0556025cef040dce 110 Hamap MF_00142 Iron-sulfur cluster assembly protein CyaY [cyaY]. 1 107 25.305 T 12-10-2018 IPR002908 Frataxin/CyaY GO:0008199|GO:0016226 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 VAPA_1c11970 c9102861ef4d90bf0556025cef040dce 110 Pfam PF01491 Frataxin-like domain 1 104 2.3E-24 T 12-10-2018 IPR002908 Frataxin/CyaY GO:0008199|GO:0016226 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 VAPA_1c11970 c9102861ef4d90bf0556025cef040dce 110 SUPERFAMILY SSF55387 1 107 6.8E-31 T 12-10-2018 VAPA_1c11970 c9102861ef4d90bf0556025cef040dce 110 SMART SM01219 1 108 2.9E-47 T 12-10-2018 IPR002908 Frataxin/CyaY GO:0008199|GO:0016226 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 VAPA_1c02890 51bfff68fcd6a12d85d6988298414dd4 325 SUPERFAMILY SSF51735 1 185 2.73E-14 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c02890 51bfff68fcd6a12d85d6988298414dd4 325 Gene3D G3DSA:1.10.1040.10 197 325 5.3E-40 T 12-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 VAPA_1c02890 51bfff68fcd6a12d85d6988298414dd4 325 Pfam PF02558 Ketopantoate reductase PanE/ApbA 3 167 2.4E-20 T 12-10-2018 IPR013332 Ketopantoate reductase, N-terminal domain VAPA_1c02890 51bfff68fcd6a12d85d6988298414dd4 325 Pfam PF08546 Ketopantoate reductase PanE/ApbA C terminal 198 317 2.6E-21 T 12-10-2018 IPR013752 Ketopantoate reductase, C-terminal domain VAPA_1c02890 51bfff68fcd6a12d85d6988298414dd4 325 SUPERFAMILY SSF48179 198 317 1.7E-23 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 VAPA_1c02890 51bfff68fcd6a12d85d6988298414dd4 325 Gene3D G3DSA:3.40.50.720 1 196 1.4E-66 T 12-10-2018 VAPA_2c03040 82263f20ea267de50dd5f6ebf50cc7d3 376 Gene3D G3DSA:3.30.360.10 125 312 1.9E-60 T 12-10-2018 VAPA_2c03040 82263f20ea267de50dd5f6ebf50cc7d3 376 Pfam PF16653 Saccharopine dehydrogenase C-terminal domain 124 344 2.6E-12 T 12-10-2018 IPR032095 Saccharopine dehydrogenase, C-terminal Reactome: R-HSA-71064 VAPA_2c03040 82263f20ea267de50dd5f6ebf50cc7d3 376 Gene3D G3DSA:3.40.50.720 9 345 1.9E-60 T 12-10-2018 VAPA_2c03040 82263f20ea267de50dd5f6ebf50cc7d3 376 Pfam PF03435 Saccharopine dehydrogenase NADP binding domain 9 113 3.9E-13 T 12-10-2018 IPR005097 Saccharopine dehydrogenase, NADP binding domain GO:0016491|GO:0055114 VAPA_2c03040 82263f20ea267de50dd5f6ebf50cc7d3 376 SUPERFAMILY SSF51735 7 174 2.89E-17 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_2c03040 82263f20ea267de50dd5f6ebf50cc7d3 376 SUPERFAMILY SSF55347 125 359 1.77E-56 T 12-10-2018 VAPA_1c00980 b6c73ce1993132dd53391d1c3b7f5bed 146 SUPERFAMILY SSF54637 2 143 1.21E-31 T 12-10-2018 IPR029069 HotDog domain superfamily VAPA_1c00980 b6c73ce1993132dd53391d1c3b7f5bed 146 Pfam PF01575 MaoC like domain 8 111 7.1E-18 T 12-10-2018 IPR002539 MaoC-like dehydratase domain VAPA_1c00980 b6c73ce1993132dd53391d1c3b7f5bed 146 Gene3D G3DSA:3.10.129.10 1 144 5.4E-39 T 12-10-2018 VAPA_1c04100 856c07db6e4e468986f69e9828db474d 306 Gene3D G3DSA:3.40.50.2300 129 299 2.5E-74 T 12-10-2018 VAPA_1c04100 856c07db6e4e468986f69e9828db474d 306 Gene3D G3DSA:3.40.50.2300 37 289 2.5E-74 T 12-10-2018 VAPA_1c04100 856c07db6e4e468986f69e9828db474d 306 SUPERFAMILY SSF53822 8 304 1.23E-72 T 12-10-2018 IPR028082 Periplasmic binding protein-like I VAPA_1c04100 856c07db6e4e468986f69e9828db474d 306 Pfam PF13407 Periplasmic binding protein domain 32 278 7.8E-56 T 12-10-2018 IPR025997 Periplasmic binding protein VAPA_1c19740 65fa79499a89568dd5f834f1645d29c9 389 Pfam PF00589 Phage integrase family 209 372 1.3E-12 T 12-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 VAPA_1c19740 65fa79499a89568dd5f834f1645d29c9 389 SUPERFAMILY SSF56349 92 372 2.83E-35 T 12-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 VAPA_1c19740 65fa79499a89568dd5f834f1645d29c9 389 Gene3D G3DSA:1.10.443.10 201 375 1.4E-21 T 12-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 VAPA_1c52360 b4846b74a95522b24be7e84545e5aaf4 132 Gene3D G3DSA:3.90.1030.10 1 116 4.2E-46 T 12-10-2018 IPR036373 Ribosomal protein L17 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 VAPA_1c52360 b4846b74a95522b24be7e84545e5aaf4 132 SUPERFAMILY SSF64263 1 119 1.24E-49 T 12-10-2018 IPR036373 Ribosomal protein L17 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 VAPA_1c52360 b4846b74a95522b24be7e84545e5aaf4 132 Hamap MF_01368 50S ribosomal protein L17 [rplQ]. 5 116 26.305 T 12-10-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 VAPA_1c52360 b4846b74a95522b24be7e84545e5aaf4 132 ProSitePatterns PS01167 Ribosomal protein L17 signature. 34 56 - T 12-10-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 VAPA_1c52360 b4846b74a95522b24be7e84545e5aaf4 132 Pfam PF01196 Ribosomal protein L17 20 116 9.2E-34 T 12-10-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 VAPA_1c52360 b4846b74a95522b24be7e84545e5aaf4 132 TIGRFAM TIGR00059 L17: ribosomal protein bL17 7 117 3.0E-44 T 12-10-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 VAPA_1c19150 1d0256def731ca65abaad57e559f902a 409 Gene3D G3DSA:3.90.1150.10 22 398 8.1E-138 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 VAPA_1c19150 1d0256def731ca65abaad57e559f902a 409 Pfam PF00155 Aminotransferase class I and II 34 395 1.4E-48 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 VAPA_1c19150 1d0256def731ca65abaad57e559f902a 409 Gene3D G3DSA:3.40.640.10 53 294 8.1E-138 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 VAPA_1c19150 1d0256def731ca65abaad57e559f902a 409 SUPERFAMILY SSF53383 7 400 1.36E-96 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase VAPA_1c22880 d3431d0a9e47927b9c61a1682210489e 123 Pfam PF01817 Chorismate mutase type II 32 109 3.6E-17 T 12-10-2018 IPR002701 Chorismate mutase II, prokaryotic-type GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 VAPA_1c22880 d3431d0a9e47927b9c61a1682210489e 123 SUPERFAMILY SSF48600 27 110 5.19E-22 T 12-10-2018 IPR036263 Chorismate mutase type II superfamily GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 VAPA_1c22880 d3431d0a9e47927b9c61a1682210489e 123 SMART SM00830 32 111 4.3E-23 T 12-10-2018 IPR002701 Chorismate mutase II, prokaryotic-type GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 VAPA_1c22880 d3431d0a9e47927b9c61a1682210489e 123 Gene3D G3DSA:1.20.59.10 24 118 2.6E-28 T 12-10-2018 IPR036979 Chorismate mutase domain superfamily GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 VAPA_2c00090 fa8eeb2e59374965579e080bf3806f96 1200 Gene3D G3DSA:3.40.920.10 743 947 3.1E-19 T 12-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 VAPA_2c00090 fa8eeb2e59374965579e080bf3806f96 1200 SUPERFAMILY SSF52518 28 210 5.59E-17 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold VAPA_2c00090 fa8eeb2e59374965579e080bf3806f96 1200 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 752 939 6.4E-21 T 12-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 VAPA_2c00090 fa8eeb2e59374965579e080bf3806f96 1200 SUPERFAMILY SSF53323 743 968 5.89E-27 T 12-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 VAPA_2c00090 fa8eeb2e59374965579e080bf3806f96 1200 Gene3D G3DSA:3.40.50.970 22 229 2.9E-26 T 12-10-2018 VAPA_2c00090 fa8eeb2e59374965579e080bf3806f96 1200 SUPERFAMILY SSF52518 453 639 2.03E-8 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold VAPA_1c13030 559d24ca3e7163ea7b8c932474c2372c 147 Gene3D G3DSA:3.10.129.10 9 146 1.5E-51 T 12-10-2018 VAPA_1c13030 559d24ca3e7163ea7b8c932474c2372c 147 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 27 136 1.4E-24 T 12-10-2018 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-77289 VAPA_1c13030 559d24ca3e7163ea7b8c932474c2372c 147 TIGRFAM TIGR02286 PaaD: phenylacetic acid degradation protein PaaD 27 138 6.1E-46 T 12-10-2018 IPR011973 Phenylacetic acid degradation protein PaaD GO:0016790 VAPA_1c13030 559d24ca3e7163ea7b8c932474c2372c 147 SUPERFAMILY SSF54637 8 134 3.67E-33 T 12-10-2018 IPR029069 HotDog domain superfamily VAPA_1c13030 559d24ca3e7163ea7b8c932474c2372c 147 Pfam PF03061 Thioesterase superfamily 57 129 6.2E-12 T 12-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 VAPA_1c33810 20bbb5de19de726812f451c13dfff61d 268 Pfam PF04072 Leucine carboxyl methyltransferase 22 169 1.6E-17 T 12-10-2018 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 VAPA_1c33810 20bbb5de19de726812f451c13dfff61d 268 SUPERFAMILY SSF53335 1 254 8.33E-42 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase VAPA_1c33810 20bbb5de19de726812f451c13dfff61d 268 Gene3D G3DSA:3.40.50.150 1 230 1.2E-29 T 12-10-2018 VAPA_2c07540 3fc4e9287ee0726e6210e5944c75ba35 181 Pfam PF00578 AhpC/TSA family 5 140 3.8E-15 T 12-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 VAPA_2c07540 3fc4e9287ee0726e6210e5944c75ba35 181 Gene3D G3DSA:3.40.30.10 5 169 1.7E-19 T 12-10-2018 VAPA_2c07540 3fc4e9287ee0726e6210e5944c75ba35 181 SUPERFAMILY SSF52833 1 171 8.77E-27 T 12-10-2018 IPR036249 Thioredoxin-like superfamily VAPA_1c36560 ea76200c60060a24876e017d13f1dde4 180 Gene3D G3DSA:3.40.50.450 4 177 1.1E-46 T 12-10-2018 VAPA_1c36560 ea76200c60060a24876e017d13f1dde4 180 Pfam PF05014 Nucleoside 2-deoxyribosyltransferase 13 153 6.2E-38 T 12-10-2018 IPR007710 Nucleoside 2-deoxyribosyltransferase Reactome: R-HSA-74259 VAPA_1c36560 ea76200c60060a24876e017d13f1dde4 180 SUPERFAMILY SSF52309 10 172 8.24E-38 T 12-10-2018 VAPA_2c11360 a3baccb0b37eb7dbc8f5cb11b9ba9a6a 505 Gene3D G3DSA:3.90.1300.10 61 504 2.1E-140 T 12-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 VAPA_2c11360 a3baccb0b37eb7dbc8f5cb11b9ba9a6a 505 SUPERFAMILY SSF75304 31 503 1.44E-116 T 12-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 VAPA_2c11360 a3baccb0b37eb7dbc8f5cb11b9ba9a6a 505 Pfam PF01425 Amidase 75 489 3.0E-104 T 12-10-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 VAPA_2c11360 a3baccb0b37eb7dbc8f5cb11b9ba9a6a 505 ProSitePatterns PS00571 Amidases signature. 169 200 - T 12-10-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 VAPA_1c31430 edbf80e27f8116f3fb34f0312c116dfd 170 Pfam PF08714 Formaldehyde-activating enzyme (Fae) 9 166 6.0E-70 T 12-10-2018 IPR014826 Formaldehyde-activating enzyme GO:0016051|GO:0016840 KEGG: 00030+4.1.2.43|KEGG: 00680+4.2.1.147+4.1.2.43|MetaCyc: PWY-1723|MetaCyc: PWY-1861|MetaCyc: PWY-7796 VAPA_1c31430 edbf80e27f8116f3fb34f0312c116dfd 170 TIGRFAM TIGR03126 one_C_fae: formaldehyde-activating enzyme 8 166 6.6E-75 T 12-10-2018 IPR014826 Formaldehyde-activating enzyme GO:0016051|GO:0016840 KEGG: 00030+4.1.2.43|KEGG: 00680+4.2.1.147+4.1.2.43|MetaCyc: PWY-1723|MetaCyc: PWY-1861|MetaCyc: PWY-7796 VAPA_1c31430 edbf80e27f8116f3fb34f0312c116dfd 170 SUPERFAMILY SSF54211 4 167 3.03E-67 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold VAPA_1c31430 edbf80e27f8116f3fb34f0312c116dfd 170 Gene3D G3DSA:3.30.230.60 2 170 3.6E-75 T 12-10-2018 IPR037075 Formaldehyde-activating enzyme superfamily GO:0016051|GO:0016840 KEGG: 00030+4.1.2.43|KEGG: 00680+4.2.1.147+4.1.2.43|MetaCyc: PWY-1723|MetaCyc: PWY-1861|MetaCyc: PWY-7796 VAPA_2c00800 574910f86c81417b67aa1650d61c0ff6 131 SUPERFAMILY SSF55331 2 112 5.4E-6 T 12-10-2018 IPR014347 Tautomerase/MIF superfamily VAPA_2c00800 574910f86c81417b67aa1650d61c0ff6 131 Gene3D G3DSA:3.30.429.10 3 117 2.0E-12 T 12-10-2018 IPR014347 Tautomerase/MIF superfamily VAPA_1c42950 d2ca3d1436d01376a160681fff1dd803 382 TIGRFAM TIGR00328 flhB: flagellar biosynthetic protein FlhB 8 355 1.5E-119 T 12-10-2018 IPR006136 Flagellar biosynthetic protein FlhB GO:0015031|GO:0016021|GO:0044780 VAPA_1c42950 d2ca3d1436d01376a160681fff1dd803 382 Gene3D G3DSA:3.40.1690.10 217 358 8.7E-56 T 12-10-2018 IPR029025 Type III secretion system substrate exporter, C-terminal VAPA_1c42950 d2ca3d1436d01376a160681fff1dd803 382 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 273 288 8.9E-36 T 12-10-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 VAPA_1c42950 d2ca3d1436d01376a160681fff1dd803 382 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 303 324 8.9E-36 T 12-10-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 VAPA_1c42950 d2ca3d1436d01376a160681fff1dd803 382 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 228 245 8.9E-36 T 12-10-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 VAPA_1c42950 d2ca3d1436d01376a160681fff1dd803 382 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 10 32 8.9E-36 T 12-10-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 VAPA_1c42950 d2ca3d1436d01376a160681fff1dd803 382 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 208 226 8.9E-36 T 12-10-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 VAPA_1c42950 d2ca3d1436d01376a160681fff1dd803 382 Pfam PF01312 FlhB HrpN YscU SpaS Family 8 348 1.2E-120 T 12-10-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 VAPA_1c42950 d2ca3d1436d01376a160681fff1dd803 382 SUPERFAMILY SSF160544 245 352 1.22E-40 T 12-10-2018 IPR029025 Type III secretion system substrate exporter, C-terminal VAPA_1c17640 01ff4981b95669fc4d59adb7675c3646 476 SUPERFAMILY SSF53187 15 455 5.39E-46 T 12-10-2018 VAPA_1c17640 01ff4981b95669fc4d59adb7675c3646 476 Gene3D G3DSA:3.30.70.360 205 368 3.0E-87 T 12-10-2018 VAPA_1c17640 01ff4981b95669fc4d59adb7675c3646 476 Pfam PF01546 Peptidase family M20/M25/M40 90 450 1.7E-21 T 12-10-2018 IPR002933 Peptidase M20 GO:0016787 VAPA_1c17640 01ff4981b95669fc4d59adb7675c3646 476 Gene3D G3DSA:3.40.630.10 54 435 3.0E-87 T 12-10-2018 VAPA_1c17640 01ff4981b95669fc4d59adb7675c3646 476 Pfam PF07687 Peptidase dimerisation domain 203 355 6.3E-10 T 12-10-2018 IPR011650 Peptidase M20, dimerisation domain VAPA_1c16720 46fab5af42a05b7d984d09bcd4853566 368 Gene3D G3DSA:1.10.10.10 2 118 2.0E-22 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c16720 46fab5af42a05b7d984d09bcd4853566 368 Pfam PF12727 PBP superfamily domain 142 325 1.3E-51 T 12-10-2018 IPR024370 PBP domain VAPA_1c16720 46fab5af42a05b7d984d09bcd4853566 368 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 25 81 9.9E-13 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c16720 46fab5af42a05b7d984d09bcd4853566 368 SUPERFAMILY SSF46785 5 123 3.06E-20 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c16720 46fab5af42a05b7d984d09bcd4853566 368 SUPERFAMILY SSF53850 191 340 3.83E-13 T 12-10-2018 VAPA_2c01790 4cc8a8f9fcdb9fcb8a30a52ad832bc8e 249 SMART SM00345 34 92 1.3E-11 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_2c01790 4cc8a8f9fcdb9fcb8a30a52ad832bc8e 249 Pfam PF07729 FCD domain 102 231 1.6E-18 T 12-10-2018 IPR011711 GntR, C-terminal VAPA_2c01790 4cc8a8f9fcdb9fcb8a30a52ad832bc8e 249 Pfam PF00392 Bacterial regulatory proteins, gntR family 30 92 2.7E-17 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_2c01790 4cc8a8f9fcdb9fcb8a30a52ad832bc8e 249 Gene3D G3DSA:1.20.120.530 96 248 5.8E-24 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal VAPA_2c01790 4cc8a8f9fcdb9fcb8a30a52ad832bc8e 249 Gene3D G3DSA:1.10.10.10 16 93 1.0E-16 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_2c01790 4cc8a8f9fcdb9fcb8a30a52ad832bc8e 249 SUPERFAMILY SSF48008 98 240 1.86E-17 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal VAPA_2c01790 4cc8a8f9fcdb9fcb8a30a52ad832bc8e 249 SUPERFAMILY SSF46785 26 96 9.82E-15 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_2c01790 4cc8a8f9fcdb9fcb8a30a52ad832bc8e 249 SMART SM00895 102 232 3.3E-12 T 12-10-2018 IPR011711 GntR, C-terminal VAPA_1c10400 388831ad2ced1ab27c9799962f9106b0 640 Gene3D G3DSA:1.50.10.10 264 638 5.7E-75 T 12-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 VAPA_1c10400 388831ad2ced1ab27c9799962f9106b0 640 SUPERFAMILY SSF48208 249 636 2.55E-92 T 12-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 VAPA_1c10400 388831ad2ced1ab27c9799962f9106b0 640 Pfam PF00723 Glycosyl hydrolases family 15 264 575 2.9E-25 T 12-10-2018 IPR011613 GH15-like domain Reactome: R-HSA-70221 VAPA_1c42390 6e46b1ef9f38a307d1e44bc281d97c30 390 Pfam PF02515 CoA-transferase family III 14 379 1.2E-133 T 12-10-2018 IPR003673 CoA-transferase family III GO:0003824 VAPA_1c42390 6e46b1ef9f38a307d1e44bc281d97c30 390 SUPERFAMILY SSF89796 12 386 6.67E-132 T 12-10-2018 IPR023606 CoA-transferase family III domain superfamily VAPA_1c42390 6e46b1ef9f38a307d1e44bc281d97c30 390 Gene3D G3DSA:3.40.50.10540 13 346 2.1E-140 T 12-10-2018 IPR023606 CoA-transferase family III domain superfamily VAPA_1c42390 6e46b1ef9f38a307d1e44bc281d97c30 390 Gene3D G3DSA:3.30.1540.10 234 325 2.1E-140 T 12-10-2018 VAPA_2c00520 12f00841f7425f71786c195d7add22bd 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 85 96 2.5E-39 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c00520 12f00841f7425f71786c195d7add22bd 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 133 149 2.5E-39 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c00520 12f00841f7425f71786c195d7add22bd 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 180 197 2.5E-39 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c00520 12f00841f7425f71786c195d7add22bd 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 2.5E-39 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c00520 12f00841f7425f71786c195d7add22bd 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 159 178 2.5E-39 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c00520 12f00841f7425f71786c195d7add22bd 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 215 235 2.5E-39 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c00520 12f00841f7425f71786c195d7add22bd 256 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 6 190 0.0014 T 12-10-2018 VAPA_2c00520 12f00841f7425f71786c195d7add22bd 256 SUPERFAMILY SSF51735 5 253 8.17E-77 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_2c00520 12f00841f7425f71786c195d7add22bd 256 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 251 2.6E-61 T 12-10-2018 VAPA_2c00520 12f00841f7425f71786c195d7add22bd 256 Gene3D G3DSA:3.40.50.720 2 255 1.7E-75 T 12-10-2018 VAPA_2c00520 12f00841f7425f71786c195d7add22bd 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 159 178 7.3E-8 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c00520 12f00841f7425f71786c195d7add22bd 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 85 96 7.3E-8 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c00520 12f00841f7425f71786c195d7add22bd 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 139 147 7.3E-8 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c29140 1ee36cfbc7ca14aff268a1426da13ce0 218 ProSitePatterns PS00113 Adenylate kinase signature. 81 92 - T 12-10-2018 IPR033690 Adenylate kinase, conserved site KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 VAPA_1c29140 1ee36cfbc7ca14aff268a1426da13ce0 218 Gene3D G3DSA:3.40.50.300 1 218 1.6E-76 T 12-10-2018 VAPA_1c29140 1ee36cfbc7ca14aff268a1426da13ce0 218 TIGRFAM TIGR01351 adk: adenylate kinase 2 215 1.8E-73 T 12-10-2018 IPR006259 Adenylate kinase subfamily GO:0004017|GO:0005524|GO:0016776 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 VAPA_1c29140 1ee36cfbc7ca14aff268a1426da13ce0 218 Pfam PF00406 Adenylate kinase 5 185 2.7E-56 T 12-10-2018 VAPA_1c29140 1ee36cfbc7ca14aff268a1426da13ce0 218 Hamap MF_00235 Adenylate kinase [adk]. 1 217 52.99 T 12-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 VAPA_1c29140 1ee36cfbc7ca14aff268a1426da13ce0 218 SUPERFAMILY SSF52540 1 191 5.43E-44 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c29140 1ee36cfbc7ca14aff268a1426da13ce0 218 PRINTS PR00094 Adenylate kinase signature 173 187 4.0E-36 T 12-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 VAPA_1c29140 1ee36cfbc7ca14aff268a1426da13ce0 218 PRINTS PR00094 Adenylate kinase signature 4 17 4.0E-36 T 12-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 VAPA_1c29140 1ee36cfbc7ca14aff268a1426da13ce0 218 PRINTS PR00094 Adenylate kinase signature 81 97 4.0E-36 T 12-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 VAPA_1c29140 1ee36cfbc7ca14aff268a1426da13ce0 218 PRINTS PR00094 Adenylate kinase signature 32 46 4.0E-36 T 12-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 VAPA_1c29140 1ee36cfbc7ca14aff268a1426da13ce0 218 PRINTS PR00094 Adenylate kinase signature 156 171 4.0E-36 T 12-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 VAPA_1c29140 1ee36cfbc7ca14aff268a1426da13ce0 218 Pfam PF05191 Adenylate kinase, active site lid 123 158 8.3E-18 T 12-10-2018 IPR007862 Adenylate kinase, active site lid domain GO:0004017 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 VAPA_1c26240 7b544b7d58d2cd945e78bb2761e9e9c7 317 Pfam PF02653 Branched-chain amino acid transport system / permease component 10 262 2.5E-36 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 VAPA_1c22350 f7f876d75ebca2e22d8c0b330820bd5d 341 Gene3D G3DSA:1.10.10.60 230 334 1.2E-31 T 12-10-2018 VAPA_1c22350 f7f876d75ebca2e22d8c0b330820bd5d 341 Pfam PF12833 Helix-turn-helix domain 252 331 5.6E-25 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 VAPA_1c22350 f7f876d75ebca2e22d8c0b330820bd5d 341 SUPERFAMILY SSF46689 282 332 9.88E-8 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 VAPA_1c22350 f7f876d75ebca2e22d8c0b330820bd5d 341 Pfam PF14525 AraC-binding-like domain 27 203 3.9E-37 T 12-10-2018 IPR035418 Transcription regulator HTH, AraC- type, ligand binding domain-like VAPA_1c22350 f7f876d75ebca2e22d8c0b330820bd5d 341 SMART SM00342 246 330 3.7E-24 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 VAPA_1c22350 f7f876d75ebca2e22d8c0b330820bd5d 341 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 283 326 - T 12-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 VAPA_1c22350 f7f876d75ebca2e22d8c0b330820bd5d 341 SUPERFAMILY SSF46689 230 279 6.74E-7 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 VAPA_1c37100 1ac46dc754b62431e8672dbc65e7070e 490 SUPERFAMILY SSF75304 3 474 2.62E-99 T 12-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 VAPA_1c37100 1ac46dc754b62431e8672dbc65e7070e 490 Gene3D G3DSA:3.90.1300.10 8 488 5.4E-109 T 12-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 VAPA_1c37100 1ac46dc754b62431e8672dbc65e7070e 490 Pfam PF01425 Amidase 38 463 3.2E-69 T 12-10-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 VAPA_1c21180 f42e7986c764dbe3cb2ceaf0d4671607 101 SUPERFAMILY SSF47413 24 88 1.04E-14 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 VAPA_1c21180 f42e7986c764dbe3cb2ceaf0d4671607 101 SMART SM00530 30 85 3.0E-10 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 VAPA_1c21180 f42e7986c764dbe3cb2ceaf0d4671607 101 Gene3D G3DSA:1.10.260.40 8 90 6.3E-18 T 12-10-2018 VAPA_1c21180 f42e7986c764dbe3cb2ceaf0d4671607 101 Pfam PF01381 Helix-turn-helix 31 83 8.0E-11 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 VAPA_1c49850 fb100aad0e6c08da059e74cf8f44c9f0 161 Hamap MF_00048 UPF0102 protein YraN [yraN]. 6 126 17.146 T 12-10-2018 IPR003509 Uncharacterised protein family UPF0102 VAPA_1c49850 fb100aad0e6c08da059e74cf8f44c9f0 161 SUPERFAMILY SSF52980 7 94 9.25E-13 T 12-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 VAPA_1c49850 fb100aad0e6c08da059e74cf8f44c9f0 161 Gene3D G3DSA:3.40.1350.10 12 106 1.3E-19 T 12-10-2018 IPR011856 tRNA endonuclease-like domain superfamily GO:0003676|GO:0004518 VAPA_1c49850 fb100aad0e6c08da059e74cf8f44c9f0 161 Pfam PF02021 Uncharacterised protein family UPF0102 13 95 1.6E-19 T 12-10-2018 IPR003509 Uncharacterised protein family UPF0102 VAPA_2c03250 b11a8a55d533d8719e63fc45956b3fd0 215 SUPERFAMILY SSF52540 6 151 3.62E-12 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_2c03250 b11a8a55d533d8719e63fc45956b3fd0 215 Gene3D G3DSA:3.40.50.300 4 181 6.2E-15 T 12-10-2018 VAPA_1c04780 19ef2288e8fdf3d4588537958f55b4f7 261 TIGRFAM TIGR01704 MTA/SAH-Nsdase: MTA/SAH nucleosidase 5 241 1.6E-45 T 12-10-2018 IPR010049 MTA/SAH nucleosidase GO:0008782|GO:0008930|GO:0009164|GO:0019509 KEGG: 00270+3.2.2.9|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 VAPA_1c04780 19ef2288e8fdf3d4588537958f55b4f7 261 Gene3D G3DSA:3.40.50.1580 1 244 1.2E-72 T 12-10-2018 VAPA_1c04780 19ef2288e8fdf3d4588537958f55b4f7 261 SUPERFAMILY SSF53167 5 244 4.06E-62 T 12-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 VAPA_1c04780 19ef2288e8fdf3d4588537958f55b4f7 261 Pfam PF01048 Phosphorylase superfamily 5 246 5.1E-53 T 12-10-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 VAPA_1c41520 7a99993b1497a365ad0c6319bbb7c763 302 Gene3D G3DSA:1.10.3720.10 58 299 1.5E-54 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c41520 7a99993b1497a365ad0c6319bbb7c763 302 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 95 299 1.1E-9 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 VAPA_1c41520 7a99993b1497a365ad0c6319bbb7c763 302 SUPERFAMILY SSF161098 62 289 2.88E-48 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c36590 55a1d601a691e9f22080993d7861df85 119 Gene3D G3DSA:1.10.490.10 1 119 2.7E-35 T 12-10-2018 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 VAPA_1c36590 55a1d601a691e9f22080993d7861df85 119 SUPERFAMILY SSF46458 2 117 1.91E-25 T 12-10-2018 IPR009050 Globin-like superfamily VAPA_1c36590 55a1d601a691e9f22080993d7861df85 119 ProSitePatterns PS01213 Protozoan/cyanobacterial globins signature. 51 71 - T 12-10-2018 IPR019795 Globin, bacterial-like, conserved site GO:0015671|GO:0019825 VAPA_1c36590 55a1d601a691e9f22080993d7861df85 119 Pfam PF01152 Bacterial-like globin 4 115 2.0E-15 T 12-10-2018 IPR001486 Truncated hemoglobin GO:0019825 VAPA_1c07070 1511122926bc92d06a132bdcdc0d8c05 366 Pfam PF00296 Luciferase-like monooxygenase 1 321 3.2E-49 T 12-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 VAPA_1c07070 1511122926bc92d06a132bdcdc0d8c05 366 Gene3D G3DSA:3.20.20.30 1 363 1.2E-83 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 VAPA_1c07070 1511122926bc92d06a132bdcdc0d8c05 366 SUPERFAMILY SSF51679 1 361 3.14E-73 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 VAPA_1c43820 8f95e7dbc855581ffa7dba7fb05198fe 497 PIRSF PIRSF016636 1 497 6.7E-153 T 12-10-2018 IPR024194 Alginate O-acetyltransferase AlgI/D-alanyl transfer protein DltB VAPA_1c43820 8f95e7dbc855581ffa7dba7fb05198fe 497 PIRSF PIRSF500217 1 497 1.0E-152 T 12-10-2018 IPR028362 Alginate O-acetyltransferase AlgI GO:0042121 VAPA_1c43820 8f95e7dbc855581ffa7dba7fb05198fe 497 Pfam PF03062 MBOAT, membrane-bound O-acyltransferase family 48 379 2.1E-30 T 12-10-2018 IPR004299 Membrane bound O-acyl transferase, MBOAT VAPA_1c10480 5ac424f697f9d79f7ae9e7964e7dcefd 327 Gene3D G3DSA:3.40.190.10 110 303 6.7E-53 T 12-10-2018 VAPA_1c10480 5ac424f697f9d79f7ae9e7964e7dcefd 327 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 17 73 6.3E-21 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c10480 5ac424f697f9d79f7ae9e7964e7dcefd 327 Gene3D G3DSA:1.10.10.10 13 102 1.7E-24 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c10480 5ac424f697f9d79f7ae9e7964e7dcefd 327 SUPERFAMILY SSF53850 102 304 3.1E-35 T 12-10-2018 VAPA_1c10480 5ac424f697f9d79f7ae9e7964e7dcefd 327 Pfam PF03466 LysR substrate binding domain 100 304 3.9E-31 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_1c10480 5ac424f697f9d79f7ae9e7964e7dcefd 327 Gene3D G3DSA:3.40.190.10 170 276 6.7E-53 T 12-10-2018 VAPA_1c10480 5ac424f697f9d79f7ae9e7964e7dcefd 327 SUPERFAMILY SSF46785 12 95 4.86E-22 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c10480 5ac424f697f9d79f7ae9e7964e7dcefd 327 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 51 62 4.8E-9 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c10480 5ac424f697f9d79f7ae9e7964e7dcefd 327 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 41 4.8E-9 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c10480 5ac424f697f9d79f7ae9e7964e7dcefd 327 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 51 4.8E-9 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c34910 18fe83f55db3bdcaf4d402c2ab718bf1 357 Gene3D G3DSA:3.40.50.300 1 233 6.3E-56 T 12-10-2018 VAPA_1c34910 18fe83f55db3bdcaf4d402c2ab718bf1 357 ProSitePatterns PS00211 ABC transporters family signature. 131 145 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_1c34910 18fe83f55db3bdcaf4d402c2ab718bf1 357 Pfam PF00005 ABC transporter 26 158 2.3E-26 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c34910 18fe83f55db3bdcaf4d402c2ab718bf1 357 SMART SM00382 27 210 1.8E-8 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c34910 18fe83f55db3bdcaf4d402c2ab718bf1 357 SUPERFAMILY SSF52540 3 238 1.69E-62 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c34910 18fe83f55db3bdcaf4d402c2ab718bf1 357 Gene3D G3DSA:2.40.50.100 236 343 1.3E-7 T 12-10-2018 VAPA_1c34910 18fe83f55db3bdcaf4d402c2ab718bf1 357 Gene3D G3DSA:2.40.50.140 288 332 1.3E-7 T 12-10-2018 VAPA_1c34910 18fe83f55db3bdcaf4d402c2ab718bf1 357 SUPERFAMILY SSF50331 234 349 2.11E-21 T 12-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal VAPA_1c34910 18fe83f55db3bdcaf4d402c2ab718bf1 357 Pfam PF08402 TOBE domain 270 341 4.6E-7 T 12-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 VAPA_1c46620 21c52e1dd6264e34519589db9f64e3d1 415 Gene3D G3DSA:3.40.50.10540 5 406 5.8E-154 T 12-10-2018 IPR023606 CoA-transferase family III domain superfamily VAPA_1c46620 21c52e1dd6264e34519589db9f64e3d1 415 Hamap MF_00742 Formyl-CoA:oxalate CoA-transferase [frc]. 1 415 63.829 T 12-10-2018 IPR017659 Formyl-CoA:oxalate CoA-transferase GO:0033608 MetaCyc: PWY-6695 VAPA_1c46620 21c52e1dd6264e34519589db9f64e3d1 415 Gene3D G3DSA:3.30.1540.10 242 338 5.8E-154 T 12-10-2018 VAPA_1c46620 21c52e1dd6264e34519589db9f64e3d1 415 Pfam PF02515 CoA-transferase family III 5 392 1.2E-101 T 12-10-2018 IPR003673 CoA-transferase family III GO:0003824 VAPA_1c46620 21c52e1dd6264e34519589db9f64e3d1 415 TIGRFAM TIGR03253 oxalate_frc: formyl-CoA transferase 3 415 1.3E-217 T 12-10-2018 IPR017659 Formyl-CoA:oxalate CoA-transferase GO:0033608 MetaCyc: PWY-6695 VAPA_1c46620 21c52e1dd6264e34519589db9f64e3d1 415 SUPERFAMILY SSF89796 1 415 8.63E-123 T 12-10-2018 IPR023606 CoA-transferase family III domain superfamily VAPA_1c33570 45a4a729c426d5ed81f7c60d1c6f6f00 781 Gene3D G3DSA:3.20.20.210 402 775 0.0 T 12-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 VAPA_1c33570 45a4a729c426d5ed81f7c60d1c6f6f00 781 TIGRFAM TIGR01371 met_syn_B12ind: 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase 8 776 0.0 T 12-10-2018 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 VAPA_1c33570 45a4a729c426d5ed81f7c60d1c6f6f00 781 Pfam PF08267 Cobalamin-independent synthase, N-terminal domain 5 326 2.5E-114 T 12-10-2018 IPR013215 Cobalamin-independent methionine synthase MetE, N-terminal GO:0003871|GO:0008270|GO:0008652 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 VAPA_1c33570 45a4a729c426d5ed81f7c60d1c6f6f00 781 SUPERFAMILY SSF51726 410 777 9.29E-114 T 12-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 VAPA_1c33570 45a4a729c426d5ed81f7c60d1c6f6f00 781 SUPERFAMILY SSF51726 5 406 1.29E-110 T 12-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 VAPA_1c33570 45a4a729c426d5ed81f7c60d1c6f6f00 781 Hamap MF_00172 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [metE]. 3 777 36.437 T 12-10-2018 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 VAPA_1c33570 45a4a729c426d5ed81f7c60d1c6f6f00 781 PIRSF PIRSF000382 2 781 0.0 T 12-10-2018 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 VAPA_1c33570 45a4a729c426d5ed81f7c60d1c6f6f00 781 Gene3D G3DSA:3.20.20.210 7 537 0.0 T 12-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 VAPA_1c33570 45a4a729c426d5ed81f7c60d1c6f6f00 781 Pfam PF01717 Cobalamin-independent synthase, Catalytic domain 444 772 1.0E-148 T 12-10-2018 IPR002629 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 VAPA_1c14940 4b51b7f92a33b027f0355931d55a6a4b 122 Pfam PF16137 Domain of unknown function (DUF4845) 39 117 3.7E-19 T 12-10-2018 IPR032314 Protein of unknown function DUF4845 VAPA_1c33350 dad6f0086afb82cdd4798beb1556b9d4 299 SUPERFAMILY SSF56601 40 297 9.05E-79 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like VAPA_1c33350 dad6f0086afb82cdd4798beb1556b9d4 299 Gene3D G3DSA:3.40.710.10 35 299 1.7E-80 T 12-10-2018 VAPA_1c33350 dad6f0086afb82cdd4798beb1556b9d4 299 PRINTS PR00118 Beta-lactamase class A signature 230 245 4.5E-75 T 12-10-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 VAPA_1c33350 dad6f0086afb82cdd4798beb1556b9d4 299 PRINTS PR00118 Beta-lactamase class A signature 213 228 4.5E-75 T 12-10-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 VAPA_1c33350 dad6f0086afb82cdd4798beb1556b9d4 299 PRINTS PR00118 Beta-lactamase class A signature 42 66 4.5E-75 T 12-10-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 VAPA_1c33350 dad6f0086afb82cdd4798beb1556b9d4 299 PRINTS PR00118 Beta-lactamase class A signature 115 140 4.5E-75 T 12-10-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 VAPA_1c33350 dad6f0086afb82cdd4798beb1556b9d4 299 PRINTS PR00118 Beta-lactamase class A signature 151 175 4.5E-75 T 12-10-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 VAPA_1c33350 dad6f0086afb82cdd4798beb1556b9d4 299 PRINTS PR00118 Beta-lactamase class A signature 73 90 4.5E-75 T 12-10-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 VAPA_1c33350 dad6f0086afb82cdd4798beb1556b9d4 299 PRINTS PR00118 Beta-lactamase class A signature 177 202 4.5E-75 T 12-10-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 VAPA_1c33350 dad6f0086afb82cdd4798beb1556b9d4 299 ProSitePatterns PS00146 Beta-lactamase class-A active site. 75 90 - T 12-10-2018 IPR023650 Beta-lactamase, class-A active site KEGG: 00311+3.5.2.6 VAPA_1c33350 dad6f0086afb82cdd4798beb1556b9d4 299 Pfam PF13354 Beta-lactamase enzyme family 63 270 2.1E-39 T 12-10-2018 VAPA_1c21020 e8335d02e31b54b1199ba694a9929dd8 448 Gene3D G3DSA:1.20.1440.30 147 284 8.4E-70 T 12-10-2018 VAPA_1c21020 e8335d02e31b54b1199ba694a9929dd8 448 SUPERFAMILY SSF159501 9 429 9.42E-129 T 12-10-2018 VAPA_1c21020 e8335d02e31b54b1199ba694a9929dd8 448 Pfam PF05139 Erythromycin esterase 65 422 3.4E-115 T 12-10-2018 IPR007815 Erythromycin esterase GO:0046677 VAPA_1c21020 e8335d02e31b54b1199ba694a9929dd8 448 Gene3D G3DSA:3.30.1870.10 66 146 8.4E-70 T 12-10-2018 VAPA_1c21020 e8335d02e31b54b1199ba694a9929dd8 448 PIRSF PIRSF036794 2 434 1.9E-117 T 12-10-2018 IPR014622 Uncharacterised conserved protein UCP036794, erythromycin esterase-type VAPA_1c21020 e8335d02e31b54b1199ba694a9929dd8 448 Gene3D G3DSA:3.40.1660.10 17 423 8.4E-70 T 12-10-2018 VAPA_1c52230 32dba5217b4c81aae4a8fc2fcf64408d 140 Gene3D G3DSA:1.10.10.10 1 137 3.8E-30 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c52230 32dba5217b4c81aae4a8fc2fcf64408d 140 SUPERFAMILY SSF46785 4 136 3.67E-26 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c52230 32dba5217b4c81aae4a8fc2fcf64408d 140 SMART SM00347 22 122 2.5E-12 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 VAPA_1c52230 32dba5217b4c81aae4a8fc2fcf64408d 140 Pfam PF12802 MarR family 29 86 1.1E-10 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 VAPA_1c52230 32dba5217b4c81aae4a8fc2fcf64408d 140 PRINTS PR00598 Bacterial regulatory protein MarR family signature 82 98 4.4E-6 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 VAPA_1c52230 32dba5217b4c81aae4a8fc2fcf64408d 140 PRINTS PR00598 Bacterial regulatory protein MarR family signature 112 132 4.4E-6 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 VAPA_1c52230 32dba5217b4c81aae4a8fc2fcf64408d 140 PRINTS PR00598 Bacterial regulatory protein MarR family signature 46 62 4.4E-6 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 VAPA_2c02480 b99a2e69dc292b86216560ed0a6870f0 179 SUPERFAMILY SSF51182 74 167 2.31E-16 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily VAPA_2c02480 b99a2e69dc292b86216560ed0a6870f0 179 Pfam PF07883 Cupin domain 92 163 4.8E-10 T 12-10-2018 IPR013096 Cupin 2, conserved barrel VAPA_2c02480 b99a2e69dc292b86216560ed0a6870f0 179 Gene3D G3DSA:2.60.120.10 57 170 4.4E-19 T 12-10-2018 IPR014710 RmlC-like jelly roll fold VAPA_1c50490 c1f23347dc0f7958bc8b916e215085cc 512 Pfam PF00005 ABC transporter 28 177 9.8E-27 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c50490 c1f23347dc0f7958bc8b916e215085cc 512 ProSitePatterns PS00211 ABC transporters family signature. 407 421 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_1c50490 c1f23347dc0f7958bc8b916e215085cc 512 SMART SM00382 287 491 8.9E-6 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c50490 c1f23347dc0f7958bc8b916e215085cc 512 SMART SM00382 37 225 5.0E-12 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c50490 c1f23347dc0f7958bc8b916e215085cc 512 Gene3D G3DSA:3.40.50.300 1 250 9.4E-59 T 12-10-2018 VAPA_1c50490 c1f23347dc0f7958bc8b916e215085cc 512 Pfam PF00005 ABC transporter 279 434 5.8E-18 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c50490 c1f23347dc0f7958bc8b916e215085cc 512 SUPERFAMILY SSF52540 279 496 6.68E-39 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c50490 c1f23347dc0f7958bc8b916e215085cc 512 Gene3D G3DSA:3.40.50.300 276 510 5.3E-41 T 12-10-2018 VAPA_1c50490 c1f23347dc0f7958bc8b916e215085cc 512 SUPERFAMILY SSF52540 12 238 4.64E-55 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c03830 06f4a36c21100bb3a4f674b57c6b84ad 162 Pfam PF07331 Tripartite tricarboxylate transporter TctB family 10 152 2.9E-19 T 12-10-2018 IPR009936 Protein of unknown function DUF1468 VAPA_1c36540 c5f953fa40058876edaa0f3b6b428be3 270 Pfam PF01925 Sulfite exporter TauE/SafE 34 264 3.5E-26 T 12-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 VAPA_1c16700 5a007e095d571ae308371a6c8be18e98 430 SUPERFAMILY SSF56436 200 428 7.16E-35 T 12-10-2018 IPR016187 C-type lectin fold VAPA_1c16700 5a007e095d571ae308371a6c8be18e98 430 Pfam PF03781 Sulfatase-modifying factor enzyme 1 222 359 1.8E-17 T 12-10-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 VAPA_1c16700 5a007e095d571ae308371a6c8be18e98 430 Gene3D G3DSA:3.90.1580.10 198 376 1.7E-21 T 12-10-2018 VAPA_2c03900 eea9dd1477cc009a44cbfcdd58ddc5e3 227 ProSitePatterns PS00211 ABC transporters family signature. 148 162 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_2c03900 eea9dd1477cc009a44cbfcdd58ddc5e3 227 Gene3D G3DSA:3.40.50.300 5 227 8.8E-63 T 12-10-2018 VAPA_2c03900 eea9dd1477cc009a44cbfcdd58ddc5e3 227 Pfam PF00005 ABC transporter 26 175 4.0E-30 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_2c03900 eea9dd1477cc009a44cbfcdd58ddc5e3 227 SMART SM00382 35 224 2.4E-12 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_2c03900 eea9dd1477cc009a44cbfcdd58ddc5e3 227 SUPERFAMILY SSF52540 7 225 3.22E-62 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c42600 0dff2ceaa8cff692e11e55d48101d66f 251 Pfam PF00899 ThiF family 9 243 2.2E-62 T 12-10-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 VAPA_1c42600 0dff2ceaa8cff692e11e55d48101d66f 251 Gene3D G3DSA:3.40.50.720 1 251 1.1E-90 T 12-10-2018 VAPA_1c42600 0dff2ceaa8cff692e11e55d48101d66f 251 SUPERFAMILY SSF69572 2 249 5.23E-83 T 12-10-2018 IPR035985 Ubiquitin-activating enzyme GO:0008641 VAPA_1c17330 60d58f6946262096c12e8cb853744f9e 335 Gene3D G3DSA:2.130.10.10 241 328 1.6E-21 T 12-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 VAPA_1c17330 60d58f6946262096c12e8cb853744f9e 335 SUPERFAMILY SSF50974 8 328 8.89E-70 T 12-10-2018 IPR011045 Nitrous oxide reductase, N-terminal Reactome: R-HSA-114608 VAPA_1c17330 60d58f6946262096c12e8cb853744f9e 335 Pfam PF10282 Lactonase, 7-bladed beta-propeller 113 306 1.4E-6 T 12-10-2018 IPR019405 Lactonase, 7-bladed beta propeller VAPA_1c17330 60d58f6946262096c12e8cb853744f9e 335 Gene3D G3DSA:2.130.10.10 27 209 4.9E-25 T 12-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 VAPA_1c12270 bef509b3337ecf0f3168ea2622c90bd5 202 SUPERFAMILY SSF54211 94 186 1.64E-33 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold VAPA_1c12270 bef509b3337ecf0f3168ea2622c90bd5 202 Pfam PF00475 Imidazoleglycerol-phosphate dehydratase 38 181 3.5E-63 T 12-10-2018 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 VAPA_1c12270 bef509b3337ecf0f3168ea2622c90bd5 202 Gene3D G3DSA:3.30.230.40 1 96 6.8E-39 T 12-10-2018 IPR038494 Imidazole glycerol phosphate dehydratase domain superfamily KEGG: 00340+4.2.1.19 VAPA_1c12270 bef509b3337ecf0f3168ea2622c90bd5 202 Hamap MF_00076 Imidazoleglycerol-phosphate dehydratase [hisB]. 9 202 42.741 T 12-10-2018 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 VAPA_1c12270 bef509b3337ecf0f3168ea2622c90bd5 202 Gene3D G3DSA:3.30.230.40 97 202 2.1E-35 T 12-10-2018 IPR038494 Imidazole glycerol phosphate dehydratase domain superfamily KEGG: 00340+4.2.1.19 VAPA_1c12270 bef509b3337ecf0f3168ea2622c90bd5 202 ProSitePatterns PS00954 Imidazoleglycerol-phosphate dehydratase signature 1. 68 81 - T 12-10-2018 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 VAPA_1c12270 bef509b3337ecf0f3168ea2622c90bd5 202 SUPERFAMILY SSF54211 9 93 3.54E-34 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold VAPA_1c12270 bef509b3337ecf0f3168ea2622c90bd5 202 ProSitePatterns PS00955 Imidazoleglycerol-phosphate dehydratase signature 2. 163 175 - T 12-10-2018 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 VAPA_1c53330 fb20fa16336b60dede59b41cee53665e 272 Pfam PF01261 Xylose isomerase-like TIM barrel 21 217 2.2E-30 T 12-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain VAPA_1c53330 fb20fa16336b60dede59b41cee53665e 272 PIRSF PIRSF006241 1 272 6.0E-88 T 12-10-2018 IPR026040 Hydroxypyruvate isomerase-like VAPA_1c53330 fb20fa16336b60dede59b41cee53665e 272 SUPERFAMILY SSF51658 1 268 3.01E-77 T 12-10-2018 IPR036237 Xylose isomerase-like superfamily VAPA_1c53330 fb20fa16336b60dede59b41cee53665e 272 Gene3D G3DSA:3.20.20.150 1 272 2.4E-71 T 12-10-2018 VAPA_2c04910 ccede5e93c4b271ff6943986ef418021 320 Pfam PF14572 Phosphoribosyl synthetase-associated domain 215 315 1.6E-10 T 12-10-2018 IPR005946 Ribose-phosphate pyrophosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 VAPA_2c04910 ccede5e93c4b271ff6943986ef418021 320 SUPERFAMILY SSF53271 1 154 8.19E-32 T 12-10-2018 IPR029057 Phosphoribosyltransferase-like VAPA_2c04910 ccede5e93c4b271ff6943986ef418021 320 SMART SM01400 1 121 1.1E-39 T 12-10-2018 VAPA_2c04910 ccede5e93c4b271ff6943986ef418021 320 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 1 315 6.7E-58 T 12-10-2018 IPR005946 Ribose-phosphate pyrophosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 VAPA_2c04910 ccede5e93c4b271ff6943986ef418021 320 Gene3D G3DSA:3.40.50.2020 5 312 1.9E-74 T 12-10-2018 VAPA_2c04910 ccede5e93c4b271ff6943986ef418021 320 SUPERFAMILY SSF53271 164 315 1.26E-25 T 12-10-2018 IPR029057 Phosphoribosyltransferase-like VAPA_2c04910 ccede5e93c4b271ff6943986ef418021 320 Gene3D G3DSA:3.40.50.2020 149 301 1.9E-74 T 12-10-2018 VAPA_2c04910 ccede5e93c4b271ff6943986ef418021 320 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 1 121 3.1E-26 T 12-10-2018 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 VAPA_2c12340 ae8525b31065d49fa74eecd40cc2b461 391 ProSitePatterns PS00557 FMN-dependent alpha-hydroxy acid dehydrogenases active site. 278 284 - T 12-10-2018 IPR008259 FMN-dependent alpha-hydroxy acid dehydrogenase, active site GO:0016491|GO:0055114 Reactome: R-HSA-9033241 VAPA_2c12340 ae8525b31065d49fa74eecd40cc2b461 391 Pfam PF01070 FMN-dependent dehydrogenase 12 380 3.4E-124 T 12-10-2018 IPR000262 FMN-dependent dehydrogenase GO:0016491 Reactome: R-HSA-9033241 VAPA_2c12340 ae8525b31065d49fa74eecd40cc2b461 391 SUPERFAMILY SSF51395 4 380 3.66E-88 T 12-10-2018 VAPA_2c12340 ae8525b31065d49fa74eecd40cc2b461 391 Gene3D G3DSA:3.20.20.70 2 386 2.9E-124 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 VAPA_2c12340 ae8525b31065d49fa74eecd40cc2b461 391 PIRSF PIRSF000138 1 385 5.9E-124 T 12-10-2018 IPR012133 Alpha-hydroxy acid dehydrogenase, FMN-dependent GO:0010181|GO:0016491|GO:0055114 Reactome: R-HSA-9033241 VAPA_1c44700 bba19a580dfdf1b01f32e7f1b160bebe 176 Pfam PF06892 Phage regulatory protein CII (CP76) 26 110 3.2E-7 T 12-10-2018 IPR009679 Bacteriophage 186, CII VAPA_1c26800 d3b8e584187051cd6da2d65d8dd20077 276 Gene3D G3DSA:3.40.190.10 131 235 3.3E-28 T 12-10-2018 VAPA_1c26800 d3b8e584187051cd6da2d65d8dd20077 276 SUPERFAMILY SSF53850 44 261 2.17E-26 T 12-10-2018 VAPA_1c26800 d3b8e584187051cd6da2d65d8dd20077 276 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 44 259 1.0E-20 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF VAPA_1c26800 d3b8e584187051cd6da2d65d8dd20077 276 Gene3D G3DSA:3.40.190.10 40 262 3.3E-28 T 12-10-2018 VAPA_1c04130 7104088a9ee3202dd6c00c8a624a4e12 85 SUPERFAMILY SSF47027 4 83 1.7E-26 T 12-10-2018 IPR035984 Acyl-CoA binding protein superfamily GO:0000062 VAPA_1c04130 7104088a9ee3202dd6c00c8a624a4e12 85 Pfam PF00887 Acyl CoA binding protein 7 83 2.2E-25 T 12-10-2018 IPR000582 Acyl-CoA-binding protein, ACBP GO:0000062 VAPA_1c04130 7104088a9ee3202dd6c00c8a624a4e12 85 PRINTS PR00689 Acyl-coA-binding protein signature 5 20 3.5E-16 T 12-10-2018 IPR000582 Acyl-CoA-binding protein, ACBP GO:0000062 VAPA_1c04130 7104088a9ee3202dd6c00c8a624a4e12 85 PRINTS PR00689 Acyl-coA-binding protein signature 45 60 3.5E-16 T 12-10-2018 IPR000582 Acyl-CoA-binding protein, ACBP GO:0000062 VAPA_1c04130 7104088a9ee3202dd6c00c8a624a4e12 85 PRINTS PR00689 Acyl-coA-binding protein signature 22 40 3.5E-16 T 12-10-2018 IPR000582 Acyl-CoA-binding protein, ACBP GO:0000062 VAPA_1c04130 7104088a9ee3202dd6c00c8a624a4e12 85 PRINTS PR00689 Acyl-coA-binding protein signature 66 83 3.5E-16 T 12-10-2018 IPR000582 Acyl-CoA-binding protein, ACBP GO:0000062 VAPA_1c04130 7104088a9ee3202dd6c00c8a624a4e12 85 Gene3D G3DSA:1.20.80.10 1 85 2.7E-30 T 12-10-2018 IPR014352 FERM/acyl-CoA-binding protein superfamily VAPA_1c18380 c324d5019f29c1f8086a431ad95b1ad9 234 Gene3D G3DSA:3.40.50.300 2 233 6.1E-56 T 12-10-2018 VAPA_1c18380 c324d5019f29c1f8086a431ad95b1ad9 234 ProSitePatterns PS00211 ABC transporters family signature. 132 146 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_1c18380 c324d5019f29c1f8086a431ad95b1ad9 234 SUPERFAMILY SSF52540 4 229 4.46E-56 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c18380 c324d5019f29c1f8086a431ad95b1ad9 234 Pfam PF00005 ABC transporter 20 159 8.0E-31 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c18380 c324d5019f29c1f8086a431ad95b1ad9 234 SMART SM00382 29 231 8.5E-9 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c22870 bde63f8ab26e1f9e23f33de53ce7919f 129 Pfam PF12680 SnoaL-like domain 8 113 2.7E-15 T 12-10-2018 IPR037401 SnoaL-like domain VAPA_1c22870 bde63f8ab26e1f9e23f33de53ce7919f 129 Gene3D G3DSA:3.10.450.50 2 129 5.3E-34 T 12-10-2018 VAPA_1c22870 bde63f8ab26e1f9e23f33de53ce7919f 129 SUPERFAMILY SSF54427 2 127 1.43E-23 T 12-10-2018 IPR032710 NTF2-like domain superfamily VAPA_1c36420 3e67d9ff4556d4552a672d3e9080e316 365 SUPERFAMILY SSF56954 89 338 2.75E-5 T 12-10-2018 VAPA_1c36420 3e67d9ff4556d4552a672d3e9080e316 365 Gene3D G3DSA:1.20.1600.10 85 341 1.3E-9 T 12-10-2018 VAPA_1c17860 d5403898e06323cf73319520c8c05bad 106 Gene3D G3DSA:3.30.70.1060 1 89 8.7E-13 T 12-10-2018 VAPA_1c17860 d5403898e06323cf73319520c8c05bad 106 SUPERFAMILY SSF54909 1 88 8.85E-18 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel VAPA_1c17860 d5403898e06323cf73319520c8c05bad 106 Pfam PF03795 YCII-related domain 1 85 5.2E-8 T 12-10-2018 IPR005545 YCII-related VAPA_1c45560 10b3bab01fe71ec17ddde127ed2bd080 404 Pfam PF02628 Cytochrome oxidase assembly protein 46 369 1.5E-74 T 12-10-2018 IPR003780 COX15/CtaA family GO:0006784|GO:0016021|GO:0016627|GO:0055114 Reactome: R-HSA-189451 VAPA_1c32580 567c8d66f0cb1f2dc15e0a3c41ea6345 182 SUPERFAMILY SSF51182 25 175 1.01E-22 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily VAPA_1c32580 567c8d66f0cb1f2dc15e0a3c41ea6345 182 Gene3D G3DSA:2.60.120.10 56 182 3.5E-18 T 12-10-2018 IPR014710 RmlC-like jelly roll fold VAPA_1c32580 567c8d66f0cb1f2dc15e0a3c41ea6345 182 Pfam PF07883 Cupin domain 88 157 3.0E-12 T 12-10-2018 IPR013096 Cupin 2, conserved barrel VAPA_1c49240 98dc460d14a1cd22305ced8a5e18509a 292 SUPERFAMILY SSF56534 19 278 2.35E-99 T 12-10-2018 IPR036329 Aromatic amino acid monoxygenase, C-terminal domain superfamily VAPA_1c49240 98dc460d14a1cd22305ced8a5e18509a 292 ProSitePatterns PS00367 Biopterin-dependent aromatic amino acid hydroxylases signature. 142 153 - T 12-10-2018 IPR018301 Aromatic amino acid hydroxylase, iron/copper binding site GO:0004497|GO:0005506|GO:0009072|GO:0055114 VAPA_1c49240 98dc460d14a1cd22305ced8a5e18509a 292 TIGRFAM TIGR01267 Phe4hydrox_mono: phenylalanine-4-hydroxylase 35 272 1.3E-98 T 12-10-2018 IPR005960 Phenylalanine-4-hydroxylase, monomeric form GO:0004505|GO:0006559|GO:0055114 KEGG: 00360+1.14.16.1|KEGG: 00400+1.14.16.1|KEGG: 00790+1.14.16.1|MetaCyc: PWY-6134|MetaCyc: PWY-7158 VAPA_1c49240 98dc460d14a1cd22305ced8a5e18509a 292 Pfam PF00351 Biopterin-dependent aromatic amino acid hydroxylase 44 257 1.1E-49 T 12-10-2018 IPR019774 Aromatic amino acid hydroxylase, C-terminal GO:0016714|GO:0055114 VAPA_1c49240 98dc460d14a1cd22305ced8a5e18509a 292 Gene3D G3DSA:1.10.800.10 13 290 1.5E-102 T 12-10-2018 IPR036951 Aromatic amino acid hydroxylase superfamily GO:0004497|GO:0005506|GO:0009072|GO:0055114 VAPA_1c49240 98dc460d14a1cd22305ced8a5e18509a 292 PRINTS PR00372 Biopterin-dependent aromatic amino acid hydroxylase signature 99 121 2.1E-13 T 12-10-2018 IPR019774 Aromatic amino acid hydroxylase, C-terminal GO:0016714|GO:0055114 VAPA_1c49240 98dc460d14a1cd22305ced8a5e18509a 292 PRINTS PR00372 Biopterin-dependent aromatic amino acid hydroxylase signature 236 255 2.1E-13 T 12-10-2018 IPR019774 Aromatic amino acid hydroxylase, C-terminal GO:0016714|GO:0055114 VAPA_1c49240 98dc460d14a1cd22305ced8a5e18509a 292 PRINTS PR00372 Biopterin-dependent aromatic amino acid hydroxylase signature 204 222 2.1E-13 T 12-10-2018 IPR019774 Aromatic amino acid hydroxylase, C-terminal GO:0016714|GO:0055114 VAPA_1c03710 d694080204802606a8b284aa8e7766c2 264 SUPERFAMILY SSF161098 7 253 8.37E-57 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c03710 d694080204802606a8b284aa8e7766c2 264 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 81 254 2.3E-15 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 VAPA_1c03710 d694080204802606a8b284aa8e7766c2 264 Gene3D G3DSA:1.10.3720.10 7 262 2.6E-55 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_2c12550 dd8a33d9f88b778c8689f2279b0ccc4c 264 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 77 254 5.5E-15 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 VAPA_2c12550 dd8a33d9f88b778c8689f2279b0ccc4c 264 SUPERFAMILY SSF161098 6 254 2.06E-55 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_2c12550 dd8a33d9f88b778c8689f2279b0ccc4c 264 Gene3D G3DSA:1.10.3720.10 5 263 1.9E-54 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_2c00190 b6172814ac14bf0901a0d41e7f2d3fdc 308 Pfam PF03466 LysR substrate binding domain 88 290 3.1E-31 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_2c00190 b6172814ac14bf0901a0d41e7f2d3fdc 308 Gene3D G3DSA:1.10.10.10 1 91 7.2E-21 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_2c00190 b6172814ac14bf0901a0d41e7f2d3fdc 308 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 1.9E-15 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_2c00190 b6172814ac14bf0901a0d41e7f2d3fdc 308 Gene3D G3DSA:3.40.190.10 164 267 1.2E-32 T 12-10-2018 VAPA_2c00190 b6172814ac14bf0901a0d41e7f2d3fdc 308 SUPERFAMILY SSF46785 1 84 2.22E-19 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_2c00190 b6172814ac14bf0901a0d41e7f2d3fdc 308 Gene3D G3DSA:3.40.190.10 92 280 1.2E-32 T 12-10-2018 VAPA_2c00190 b6172814ac14bf0901a0d41e7f2d3fdc 308 SUPERFAMILY SSF53850 89 293 4.34E-33 T 12-10-2018 VAPA_1c31280 261f2558385bfea7c97ccb8ccc70e028 177 Pfam PF08714 Formaldehyde-activating enzyme (Fae) 10 173 2.3E-60 T 12-10-2018 IPR014826 Formaldehyde-activating enzyme GO:0016051|GO:0016840 KEGG: 00030+4.1.2.43|KEGG: 00680+4.2.1.147+4.1.2.43|MetaCyc: PWY-1723|MetaCyc: PWY-1861|MetaCyc: PWY-7796 VAPA_1c31280 261f2558385bfea7c97ccb8ccc70e028 177 Gene3D G3DSA:3.30.230.60 6 175 2.5E-51 T 12-10-2018 IPR037075 Formaldehyde-activating enzyme superfamily GO:0016051|GO:0016840 KEGG: 00030+4.1.2.43|KEGG: 00680+4.2.1.147+4.1.2.43|MetaCyc: PWY-1723|MetaCyc: PWY-1861|MetaCyc: PWY-7796 VAPA_1c31280 261f2558385bfea7c97ccb8ccc70e028 177 SUPERFAMILY SSF54211 5 174 1.52E-54 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold VAPA_1c31280 261f2558385bfea7c97ccb8ccc70e028 177 TIGRFAM TIGR03126 one_C_fae: formaldehyde-activating enzyme 25 172 2.7E-41 T 12-10-2018 IPR014826 Formaldehyde-activating enzyme GO:0016051|GO:0016840 KEGG: 00030+4.1.2.43|KEGG: 00680+4.2.1.147+4.1.2.43|MetaCyc: PWY-1723|MetaCyc: PWY-1861|MetaCyc: PWY-7796 VAPA_1c04010 e5b1041056414479da7c3ff44066be3f 374 SUPERFAMILY SSF53822 29 372 5.65E-75 T 12-10-2018 IPR028082 Periplasmic binding protein-like I VAPA_1c04010 e5b1041056414479da7c3ff44066be3f 374 Gene3D G3DSA:3.40.50.2300 31 362 2.5E-114 T 12-10-2018 VAPA_1c04010 e5b1041056414479da7c3ff44066be3f 374 Gene3D G3DSA:3.40.50.2300 146 366 2.5E-114 T 12-10-2018 VAPA_1c04010 e5b1041056414479da7c3ff44066be3f 374 Pfam PF13458 Periplasmic binding protein 31 359 9.8E-62 T 12-10-2018 IPR028081 Leucine-binding protein domain VAPA_2c10340 8b3aee1a227854aaf718ffe83e79b1bd 279 Gene3D G3DSA:3.20.20.140 1 278 1.5E-78 T 12-10-2018 VAPA_2c10340 8b3aee1a227854aaf718ffe83e79b1bd 279 SUPERFAMILY SSF51556 5 275 2.42E-69 T 12-10-2018 IPR032466 Metal-dependent hydrolase VAPA_2c10340 8b3aee1a227854aaf718ffe83e79b1bd 279 Pfam PF04909 Amidohydrolase 11 275 1.7E-37 T 12-10-2018 IPR006680 Amidohydrolase-related GO:0016787 VAPA_1c32380 98915544573206fad4e8c4be3ae2aad7 94 Pfam PF07369 Protein of unknown function (DUF1488) 13 82 3.0E-6 T 12-10-2018 IPR009962 Protein of unknown function DUF1488 VAPA_1c32380 98915544573206fad4e8c4be3ae2aad7 94 SUPERFAMILY SSF160272 13 81 1.83E-5 T 12-10-2018 IPR036692 Shew3726-like superfamily VAPA_1c53570 8a87e3e1f5a29332575b646f5d034904 203 SUPERFAMILY SSF47616 69 203 6.68E-21 T 12-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily VAPA_1c53570 8a87e3e1f5a29332575b646f5d034904 203 Pfam PF13410 Glutathione S-transferase, C-terminal domain 123 190 6.1E-10 T 12-10-2018 VAPA_1c53570 8a87e3e1f5a29332575b646f5d034904 203 Pfam PF13417 Glutathione S-transferase, N-terminal domain 3 75 7.4E-19 T 12-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 VAPA_1c53570 8a87e3e1f5a29332575b646f5d034904 203 Gene3D G3DSA:1.20.1050.10 79 195 1.3E-72 T 12-10-2018 VAPA_1c53570 8a87e3e1f5a29332575b646f5d034904 203 SUPERFAMILY SSF52833 1 100 1.21E-22 T 12-10-2018 IPR036249 Thioredoxin-like superfamily VAPA_1c53570 8a87e3e1f5a29332575b646f5d034904 203 Gene3D G3DSA:3.40.30.10 3 199 1.3E-72 T 12-10-2018 VAPA_2c10910 6138e86a66954e4fdaeb39cb413d6cf4 299 Gene3D G3DSA:3.10.310.10 126 279 4.5E-50 T 12-10-2018 VAPA_2c10910 6138e86a66954e4fdaeb39cb413d6cf4 299 PIRSF PIRSF016184 8 298 4.3E-38 T 12-10-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 VAPA_2c10910 6138e86a66954e4fdaeb39cb413d6cf4 299 SUPERFAMILY SSF54506 13 295 5.02E-41 T 12-10-2018 VAPA_2c10910 6138e86a66954e4fdaeb39cb413d6cf4 299 Gene3D G3DSA:3.10.310.10 15 125 4.5E-50 T 12-10-2018 VAPA_2c10910 6138e86a66954e4fdaeb39cb413d6cf4 299 TIGRFAM TIGR00654 PhzF_family: phenazine biosynthesis protein, PhzF family 11 277 9.4E-30 T 12-10-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 VAPA_2c10910 6138e86a66954e4fdaeb39cb413d6cf4 299 Pfam PF02567 Phenazine biosynthesis-like protein 15 278 8.4E-30 T 12-10-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 VAPA_1c35520 b02a96e062c053fb4fee1d6c9d3a11c5 96 Pfam PF07045 Domain of unknown function (DUF1330) 3 96 4.1E-35 T 12-10-2018 IPR010753 Domain of unknown function DUF1330 VAPA_1c35520 b02a96e062c053fb4fee1d6c9d3a11c5 96 SUPERFAMILY SSF54909 1 96 6.11E-29 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel VAPA_1c35520 b02a96e062c053fb4fee1d6c9d3a11c5 96 Gene3D G3DSA:3.30.70.100 1 96 4.3E-32 T 12-10-2018 VAPA_2c00460 5c44d5a37cbac2521efe15d10241471f 329 SMART SM00829 10 322 1.3E-39 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 VAPA_2c00460 5c44d5a37cbac2521efe15d10241471f 329 SUPERFAMILY SSF51735 109 286 3.88E-41 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_2c00460 5c44d5a37cbac2521efe15d10241471f 329 Pfam PF00107 Zinc-binding dehydrogenase 149 263 1.4E-25 T 12-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 VAPA_2c00460 5c44d5a37cbac2521efe15d10241471f 329 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 88 1.2E-4 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 VAPA_2c00460 5c44d5a37cbac2521efe15d10241471f 329 Gene3D G3DSA:3.40.50.720 118 261 2.1E-88 T 12-10-2018 VAPA_2c00460 5c44d5a37cbac2521efe15d10241471f 329 Gene3D G3DSA:3.90.180.10 15 322 2.1E-88 T 12-10-2018 VAPA_2c00460 5c44d5a37cbac2521efe15d10241471f 329 SUPERFAMILY SSF50129 9 143 5.78E-28 T 12-10-2018 IPR011032 GroES-like superfamily VAPA_2c06990 268a7f8f3b9a7dc29aecac289ac9d163 319 SUPERFAMILY SSF56281 17 311 1.09E-53 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like VAPA_2c06990 268a7f8f3b9a7dc29aecac289ac9d163 319 SMART SM00849 36 222 2.3E-12 T 12-10-2018 IPR001279 Metallo-beta-lactamase VAPA_2c06990 268a7f8f3b9a7dc29aecac289ac9d163 319 Gene3D G3DSA:3.60.15.10 13 238 1.6E-42 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like VAPA_1c29930 43dac7aa3f1adf951ee41eea0b470d3c 304 Gene3D G3DSA:3.40.190.10 162 266 1.5E-65 T 12-10-2018 VAPA_1c29930 43dac7aa3f1adf951ee41eea0b470d3c 304 Gene3D G3DSA:1.10.10.10 3 89 2.0E-27 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c29930 43dac7aa3f1adf951ee41eea0b470d3c 304 Gene3D G3DSA:3.40.190.10 92 290 1.5E-65 T 12-10-2018 VAPA_1c29930 43dac7aa3f1adf951ee41eea0b470d3c 304 SUPERFAMILY SSF53850 89 298 6.36E-46 T 12-10-2018 VAPA_1c29930 43dac7aa3f1adf951ee41eea0b470d3c 304 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 62 1.1E-17 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c29930 43dac7aa3f1adf951ee41eea0b470d3c 304 SUPERFAMILY SSF46785 4 87 9.35E-21 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c29930 43dac7aa3f1adf951ee41eea0b470d3c 304 Pfam PF03466 LysR substrate binding domain 89 295 7.0E-41 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_2c08840 c501c785864848a283e66d3b61ef34e1 207 SUPERFAMILY SSF52833 2 88 5.08E-19 T 12-10-2018 IPR036249 Thioredoxin-like superfamily VAPA_2c08840 c501c785864848a283e66d3b61ef34e1 207 SUPERFAMILY SSF47616 73 199 9.19E-23 T 12-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily VAPA_2c08840 c501c785864848a283e66d3b61ef34e1 207 Gene3D G3DSA:3.40.30.10 1 81 1.2E-21 T 12-10-2018 VAPA_2c08840 c501c785864848a283e66d3b61ef34e1 207 Pfam PF02798 Glutathione S-transferase, N-terminal domain 2 76 6.4E-13 T 12-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 VAPA_2c08840 c501c785864848a283e66d3b61ef34e1 207 Gene3D G3DSA:1.20.1050.10 82 194 5.6E-28 T 12-10-2018 VAPA_2c08840 c501c785864848a283e66d3b61ef34e1 207 Pfam PF00043 Glutathione S-transferase, C-terminal domain 134 188 1.1E-4 T 12-10-2018 IPR004046 Glutathione S-transferase, C-terminal VAPA_1c43790 560257ffcafe64b69cd02316485b115b 409 Pfam PF00482 Type II secretion system (T2SS), protein F 279 401 2.1E-29 T 12-10-2018 IPR018076 Type II secretion system F domain VAPA_1c43790 560257ffcafe64b69cd02316485b115b 409 Pfam PF00482 Type II secretion system (T2SS), protein F 75 198 1.4E-33 T 12-10-2018 IPR018076 Type II secretion system F domain VAPA_1c43790 560257ffcafe64b69cd02316485b115b 409 PRINTS PR00812 Bacterial general secretion pathway protein F signature 390 409 1.9E-19 T 12-10-2018 IPR003004 GspF/PilC family VAPA_1c43790 560257ffcafe64b69cd02316485b115b 409 PRINTS PR00812 Bacterial general secretion pathway protein F signature 374 388 1.9E-19 T 12-10-2018 IPR003004 GspF/PilC family VAPA_1c43790 560257ffcafe64b69cd02316485b115b 409 PRINTS PR00812 Bacterial general secretion pathway protein F signature 71 83 1.9E-19 T 12-10-2018 IPR003004 GspF/PilC family VAPA_1c43790 560257ffcafe64b69cd02316485b115b 409 PRINTS PR00812 Bacterial general secretion pathway protein F signature 170 198 1.9E-19 T 12-10-2018 IPR003004 GspF/PilC family VAPA_1c43790 560257ffcafe64b69cd02316485b115b 409 Gene3D G3DSA:1.20.81.30 262 371 2.9E-28 T 12-10-2018 VAPA_1c43790 560257ffcafe64b69cd02316485b115b 409 Gene3D G3DSA:1.20.81.30 61 177 2.1E-31 T 12-10-2018 VAPA_1c53200 c7fff58b17c73d8482d14a9b6afe8c6d 592 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 267 321 - T 12-10-2018 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 VAPA_1c53200 c7fff58b17c73d8482d14a9b6afe8c6d 592 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 32 494 1.1E-135 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 VAPA_1c53200 c7fff58b17c73d8482d14a9b6afe8c6d 592 Gene3D G3DSA:1.20.210.10 13 555 1.1E-190 T 12-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 VAPA_1c53200 c7fff58b17c73d8482d14a9b6afe8c6d 592 TIGRFAM TIGR02891 CtaD_CoxA: cytochrome c oxidase, subunit I 23 543 6.0E-204 T 12-10-2018 IPR014241 Cytochrome c oxidase, subunit I bacterial type GO:0004129|GO:0005886|GO:0015990|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 VAPA_1c53200 c7fff58b17c73d8482d14a9b6afe8c6d 592 PRINTS PR01165 Cytochrome c oxidase subunit I signature 70 93 5.7E-73 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 VAPA_1c53200 c7fff58b17c73d8482d14a9b6afe8c6d 592 PRINTS PR01165 Cytochrome c oxidase subunit I signature 98 122 5.7E-73 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 VAPA_1c53200 c7fff58b17c73d8482d14a9b6afe8c6d 592 PRINTS PR01165 Cytochrome c oxidase subunit I signature 398 417 5.7E-73 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 VAPA_1c53200 c7fff58b17c73d8482d14a9b6afe8c6d 592 PRINTS PR01165 Cytochrome c oxidase subunit I signature 448 469 5.7E-73 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 VAPA_1c53200 c7fff58b17c73d8482d14a9b6afe8c6d 592 PRINTS PR01165 Cytochrome c oxidase subunit I signature 311 326 5.7E-73 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 VAPA_1c53200 c7fff58b17c73d8482d14a9b6afe8c6d 592 PRINTS PR01165 Cytochrome c oxidase subunit I signature 22 47 5.7E-73 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 VAPA_1c53200 c7fff58b17c73d8482d14a9b6afe8c6d 592 PRINTS PR01165 Cytochrome c oxidase subunit I signature 335 356 5.7E-73 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 VAPA_1c53200 c7fff58b17c73d8482d14a9b6afe8c6d 592 PRINTS PR01165 Cytochrome c oxidase subunit I signature 370 388 5.7E-73 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 VAPA_1c53200 c7fff58b17c73d8482d14a9b6afe8c6d 592 PRINTS PR01165 Cytochrome c oxidase subunit I signature 265 286 5.7E-73 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 VAPA_1c53200 c7fff58b17c73d8482d14a9b6afe8c6d 592 SUPERFAMILY SSF81442 20 541 2.49E-156 T 12-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 VAPA_1c12490 8c11eb62c542407d89719e99ff026a6d 151 Gene3D G3DSA:3.40.50.2300 1 142 8.3E-47 T 12-10-2018 VAPA_1c12490 8c11eb62c542407d89719e99ff026a6d 151 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 4 136 1.0E-34 T 12-10-2018 IPR023485 Phosphotyrosine protein phosphatase I VAPA_1c12490 8c11eb62c542407d89719e99ff026a6d 151 SMART SM00226 2 139 6.7E-48 T 12-10-2018 IPR023485 Phosphotyrosine protein phosphatase I VAPA_1c12490 8c11eb62c542407d89719e99ff026a6d 151 SUPERFAMILY SSF52788 1 140 1.44E-40 T 12-10-2018 IPR036196 Phosphotyrosine protein phosphatase I superfamily VAPA_1c12490 8c11eb62c542407d89719e99ff026a6d 151 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 4 21 2.3E-17 T 12-10-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 VAPA_1c12490 8c11eb62c542407d89719e99ff026a6d 151 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 74 89 2.3E-17 T 12-10-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 VAPA_1c12490 8c11eb62c542407d89719e99ff026a6d 151 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 111 126 2.3E-17 T 12-10-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 VAPA_1c12490 8c11eb62c542407d89719e99ff026a6d 151 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 40 56 2.3E-17 T 12-10-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 VAPA_1c05500 52b7fded2316273b80f944d5fff78218 192 Gene3D G3DSA:2.40.128.110 29 188 2.3E-35 T 12-10-2018 IPR036761 Lipid/polyisoprenoid-binding, YceI-like superfamily VAPA_1c05500 52b7fded2316273b80f944d5fff78218 192 Pfam PF04264 YceI-like domain 30 185 4.9E-29 T 12-10-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like VAPA_1c05500 52b7fded2316273b80f944d5fff78218 192 SMART SM00867 29 187 2.6E-40 T 12-10-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like VAPA_1c05500 52b7fded2316273b80f944d5fff78218 192 SUPERFAMILY SSF101874 31 186 4.97E-38 T 12-10-2018 IPR036761 Lipid/polyisoprenoid-binding, YceI-like superfamily VAPA_1c21980 1ceb07b5d416820e57091ba8867db92a 253 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 9 188 0.0062 T 12-10-2018 VAPA_1c21980 1ceb07b5d416820e57091ba8867db92a 253 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 250 1.5E-59 T 12-10-2018 VAPA_1c21980 1ceb07b5d416820e57091ba8867db92a 253 SUPERFAMILY SSF51735 4 251 4.2E-79 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c21980 1ceb07b5d416820e57091ba8867db92a 253 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 144 172 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 VAPA_1c21980 1ceb07b5d416820e57091ba8867db92a 253 Gene3D G3DSA:3.40.50.720 1 252 3.6E-80 T 12-10-2018 VAPA_1c21980 1ceb07b5d416820e57091ba8867db92a 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 137 145 2.0E-12 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c21980 1ceb07b5d416820e57091ba8867db92a 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 157 176 2.0E-12 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c21980 1ceb07b5d416820e57091ba8867db92a 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 2.0E-12 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c21980 1ceb07b5d416820e57091ba8867db92a 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 6.1E-43 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c21980 1ceb07b5d416820e57091ba8867db92a 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 6.1E-43 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c21980 1ceb07b5d416820e57091ba8867db92a 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 6.1E-43 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c21980 1ceb07b5d416820e57091ba8867db92a 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 6.1E-43 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c21980 1ceb07b5d416820e57091ba8867db92a 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 213 233 6.1E-43 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c21980 1ceb07b5d416820e57091ba8867db92a 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 6.1E-43 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c22790 b72cc1cee55cdd92da48d0ff9f6c3b58 295 Gene3D G3DSA:3.10.180.10 132 281 9.2E-32 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase VAPA_1c22790 b72cc1cee55cdd92da48d0ff9f6c3b58 295 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 7 115 2.7E-8 T 12-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain VAPA_1c22790 b72cc1cee55cdd92da48d0ff9f6c3b58 295 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 137 246 4.6E-17 T 12-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain VAPA_1c22790 b72cc1cee55cdd92da48d0ff9f6c3b58 295 SUPERFAMILY SSF54593 2 246 5.3E-28 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase VAPA_1c22790 b72cc1cee55cdd92da48d0ff9f6c3b58 295 Gene3D G3DSA:3.10.180.10 3 125 3.7E-29 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase VAPA_2c06910 1b59618e3d9f8b95483a3ee9fbb158d0 314 PRINTS PR00990 Ribokinase signature 13 34 1.4E-27 T 12-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 VAPA_2c06910 1b59618e3d9f8b95483a3ee9fbb158d0 314 PRINTS PR00990 Ribokinase signature 112 125 1.4E-27 T 12-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 VAPA_2c06910 1b59618e3d9f8b95483a3ee9fbb158d0 314 PRINTS PR00990 Ribokinase signature 180 195 1.4E-27 T 12-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 VAPA_2c06910 1b59618e3d9f8b95483a3ee9fbb158d0 314 PRINTS PR00990 Ribokinase signature 224 235 1.4E-27 T 12-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 VAPA_2c06910 1b59618e3d9f8b95483a3ee9fbb158d0 314 PRINTS PR00990 Ribokinase signature 40 59 1.4E-27 T 12-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 VAPA_2c06910 1b59618e3d9f8b95483a3ee9fbb158d0 314 SUPERFAMILY SSF53613 10 309 4.05E-73 T 12-10-2018 IPR029056 Ribokinase-like VAPA_2c06910 1b59618e3d9f8b95483a3ee9fbb158d0 314 Gene3D G3DSA:3.40.1190.20 2 311 5.7E-88 T 12-10-2018 IPR029056 Ribokinase-like VAPA_2c06910 1b59618e3d9f8b95483a3ee9fbb158d0 314 Pfam PF00294 pfkB family carbohydrate kinase 10 301 3.7E-58 T 12-10-2018 IPR011611 Carbohydrate kinase PfkB VAPA_2c06910 1b59618e3d9f8b95483a3ee9fbb158d0 314 Hamap MF_01987 Ribokinase [rbsK]. 9 309 23.329 T 12-10-2018 IPR011877 Ribokinase GO:0004747|GO:0006014 KEGG: 00030+2.7.1.15|Reactome: R-HSA-71336 VAPA_1c21050 b61153e81af8986d771a9146d709fa3b 137 Pfam PF00011 Hsp20/alpha crystallin family 36 135 2.7E-15 T 12-10-2018 IPR002068 Alpha crystallin/Hsp20 domain VAPA_1c21050 b61153e81af8986d771a9146d709fa3b 137 SUPERFAMILY SSF49764 25 135 1.88E-25 T 12-10-2018 IPR008978 HSP20-like chaperone VAPA_1c21050 b61153e81af8986d771a9146d709fa3b 137 Gene3D G3DSA:2.60.40.790 4 136 5.5E-23 T 12-10-2018 IPR008978 HSP20-like chaperone VAPA_1c38620 394b3295854997eec48bfd3da6f8e9eb 281 Pfam PF06276 Ferric iron reductase FhuF-like transporter 89 230 3.6E-18 T 12-10-2018 IPR022770 Ferric iron reductase FhuF domain VAPA_1c38620 394b3295854997eec48bfd3da6f8e9eb 281 TIGRFAM TIGR03951 Fe_III_red_FhuF: siderophore-iron reductase FhuF 83 267 7.0E-34 T 12-10-2018 IPR008090 Ferric iron reductase VAPA_1c43230 a431bb053536d514a796d63fea70f015 413 Gene3D G3DSA:1.10.8.410 360 413 4.9E-23 T 12-10-2018 VAPA_1c43230 a431bb053536d514a796d63fea70f015 413 Gene3D G3DSA:1.20.58.1830 2 59 4.1E-9 T 12-10-2018 VAPA_1c43230 a431bb053536d514a796d63fea70f015 413 Pfam PF00669 Bacterial flagellin N-terminal helical region 5 141 1.3E-42 T 12-10-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 VAPA_1c43230 a431bb053536d514a796d63fea70f015 413 SUPERFAMILY SSF64518 1 413 2.22E-102 T 12-10-2018 VAPA_1c43230 a431bb053536d514a796d63fea70f015 413 PRINTS PR00207 Flagellin signature 37 54 1.4E-29 T 12-10-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 VAPA_1c43230 a431bb053536d514a796d63fea70f015 413 PRINTS PR00207 Flagellin signature 111 134 1.4E-29 T 12-10-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 VAPA_1c43230 a431bb053536d514a796d63fea70f015 413 PRINTS PR00207 Flagellin signature 76 95 1.4E-29 T 12-10-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 VAPA_1c43230 a431bb053536d514a796d63fea70f015 413 Pfam PF00700 Bacterial flagellin C-terminal helical region 328 412 1.6E-28 T 12-10-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 VAPA_1c43230 a431bb053536d514a796d63fea70f015 413 Gene3D G3DSA:1.20.1330.10 60 358 2.3E-62 T 12-10-2018 VAPA_1c43230 a431bb053536d514a796d63fea70f015 413 Gene3D G3DSA:3.30.70.3070 165 312 2.3E-62 T 12-10-2018 VAPA_1c23010 a38408920282e95b9300e5ef1e1c4cb0 163 SUPERFAMILY SSF54593 6 148 9.49E-16 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase VAPA_1c23010 a38408920282e95b9300e5ef1e1c4cb0 163 Pfam PF13669 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 15 125 6.1E-24 T 12-10-2018 VAPA_1c23010 a38408920282e95b9300e5ef1e1c4cb0 163 Gene3D G3DSA:3.10.180.10 10 150 3.2E-20 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase VAPA_1c08130 2ef44a8bfac6f7d4bd7fd233ce96fc38 433 SUPERFAMILY SSF51905 1 418 2.07E-47 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c08130 2ef44a8bfac6f7d4bd7fd233ce96fc38 433 SUPERFAMILY SSF54373 275 369 2.35E-13 T 12-10-2018 VAPA_1c08130 2ef44a8bfac6f7d4bd7fd233ce96fc38 433 Gene3D G3DSA:3.30.9.10 134 371 2.1E-48 T 12-10-2018 VAPA_1c08130 2ef44a8bfac6f7d4bd7fd233ce96fc38 433 Gene3D G3DSA:3.50.50.60 100 413 2.1E-48 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c08130 2ef44a8bfac6f7d4bd7fd233ce96fc38 433 Gene3D G3DSA:3.50.50.60 1 73 2.3E-10 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c08130 2ef44a8bfac6f7d4bd7fd233ce96fc38 433 Pfam PF01266 FAD dependent oxidoreductase 2 406 4.3E-64 T 12-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 VAPA_1c15700 f7016d6408ed65bd8b3e156e0e279217 333 Pfam PF03186 CobD/Cbib protein 28 264 3.7E-25 T 12-10-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 VAPA_1c15700 f7016d6408ed65bd8b3e156e0e279217 333 Hamap MF_00024 Cobalamin biosynthesis protein CbiB [cbiB]. 1 333 60.106 T 12-10-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 VAPA_2c00470 f59dbbb285441701ec78637d803dca93 323 Gene3D G3DSA:3.40.190.150 27 313 4.6E-103 T 12-10-2018 VAPA_2c00470 f59dbbb285441701ec78637d803dca93 323 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 46 319 2.8E-75 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_2c00470 f59dbbb285441701ec78637d803dca93 323 Gene3D G3DSA:3.40.190.10 124 247 4.6E-103 T 12-10-2018 VAPA_2c00470 f59dbbb285441701ec78637d803dca93 323 PIRSF PIRSF017082 1 322 5.5E-74 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_2c00470 f59dbbb285441701ec78637d803dca93 323 SUPERFAMILY SSF53850 112 279 1.42E-10 T 12-10-2018 VAPA_1c19030 76254352673776fbbee39ec55070b87b 124 SUPERFAMILY SSF54995 1 103 2.22E-35 T 12-10-2018 IPR035980 Ribosomal protein S6 superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 VAPA_1c19030 76254352673776fbbee39ec55070b87b 124 Pfam PF01250 Ribosomal protein S6 3 90 7.9E-27 T 12-10-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 VAPA_1c19030 76254352673776fbbee39ec55070b87b 124 TIGRFAM TIGR00166 S6: ribosomal protein bS6 1 93 1.5E-32 T 12-10-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 VAPA_1c19030 76254352673776fbbee39ec55070b87b 124 ProSitePatterns PS01048 Ribosomal protein S6 signature. 43 52 - T 12-10-2018 IPR020815 Ribosomal protein S6, conserved site GO:0003735|GO:0005840|GO:0006412|GO:0019843 VAPA_1c19030 76254352673776fbbee39ec55070b87b 124 Gene3D G3DSA:3.30.70.60 1 92 3.0E-31 T 12-10-2018 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 VAPA_1c19030 76254352673776fbbee39ec55070b87b 124 Hamap MF_00360 30S ribosomal protein S6 [rpsF]. 1 94 21.795 T 12-10-2018 IPR020814 Ribosomal protein S6, plastid/chloroplast GO:0003735|GO:0005840|GO:0006412|GO:0019843 VAPA_1c14680 ca04c7afa9e48135e812365f403a4259 257 SUPERFAMILY SSF69618 4 255 1.44E-39 T 12-10-2018 IPR036108 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase superfamily GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 VAPA_1c14680 ca04c7afa9e48135e812365f403a4259 257 Pfam PF02602 Uroporphyrinogen-III synthase HemD 17 242 2.8E-25 T 12-10-2018 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 VAPA_1c14680 ca04c7afa9e48135e812365f403a4259 257 Gene3D G3DSA:3.40.50.10090 6 244 2.4E-53 T 12-10-2018 VAPA_1c14680 ca04c7afa9e48135e812365f403a4259 257 Gene3D G3DSA:3.40.50.10090 35 177 2.4E-53 T 12-10-2018 VAPA_1c13100 ddad5a81303577d6635803ff2c6a1794 335 PRINTS PR00834 HtrA/DegQ protease family signature 272 289 6.6E-32 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 VAPA_1c13100 ddad5a81303577d6635803ff2c6a1794 335 PRINTS PR00834 HtrA/DegQ protease family signature 234 258 6.6E-32 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 VAPA_1c13100 ddad5a81303577d6635803ff2c6a1794 335 PRINTS PR00834 HtrA/DegQ protease family signature 171 183 6.6E-32 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 VAPA_1c13100 ddad5a81303577d6635803ff2c6a1794 335 PRINTS PR00834 HtrA/DegQ protease family signature 192 212 6.6E-32 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 VAPA_1c13100 ddad5a81303577d6635803ff2c6a1794 335 PRINTS PR00834 HtrA/DegQ protease family signature 294 311 6.6E-32 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 VAPA_1c13100 ddad5a81303577d6635803ff2c6a1794 335 SUPERFAMILY SSF50494 105 327 2.43E-51 T 12-10-2018 IPR009003 Peptidase S1, PA clan VAPA_1c13100 ddad5a81303577d6635803ff2c6a1794 335 Pfam PF13365 Trypsin-like peptidase domain 162 301 3.4E-30 T 12-10-2018 VAPA_1c13100 ddad5a81303577d6635803ff2c6a1794 335 Gene3D G3DSA:2.40.10.120 104 332 1.8E-58 T 12-10-2018 VAPA_1c40950 a7d84d6018e194879e5b61632bfba3e9 302 ProSitePatterns PS00895 3-hydroxyisobutyrate dehydrogenase signature. 9 22 - T 12-10-2018 IPR002204 3-hydroxyisobutyrate dehydrogenase-related, conserved site GO:0016491|GO:0055114 Reactome: R-HSA-70895 VAPA_1c40950 a7d84d6018e194879e5b61632bfba3e9 302 Gene3D G3DSA:3.40.50.720 1 168 2.7E-47 T 12-10-2018 VAPA_1c40950 a7d84d6018e194879e5b61632bfba3e9 302 PIRSF PIRSF000103 1 300 1.2E-68 T 12-10-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 VAPA_1c40950 a7d84d6018e194879e5b61632bfba3e9 302 SUPERFAMILY SSF48179 170 298 8.16E-38 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 VAPA_1c40950 a7d84d6018e194879e5b61632bfba3e9 302 Gene3D G3DSA:1.10.1040.10 169 300 8.5E-39 T 12-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 VAPA_1c40950 a7d84d6018e194879e5b61632bfba3e9 302 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 171 291 2.5E-38 T 12-10-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 VAPA_1c40950 a7d84d6018e194879e5b61632bfba3e9 302 SUPERFAMILY SSF51735 5 169 3.94E-41 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c40950 a7d84d6018e194879e5b61632bfba3e9 302 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 6 168 2.8E-44 T 12-10-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 VAPA_1c40950 a7d84d6018e194879e5b61632bfba3e9 302 TIGRFAM TIGR01505 tartro_sem_red: 2-hydroxy-3-oxopropionate reductase 6 299 1.8E-116 T 12-10-2018 IPR006398 2-hydroxy-3-oxopropionate reductase GO:0008679|GO:0046487|GO:0055114 KEGG: 00630+1.1.1.60 VAPA_1c11460 a88caf3a38dee7ff3fc676371b154cc7 303 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 12 52 3.6E-5 T 12-10-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain VAPA_1c11460 a88caf3a38dee7ff3fc676371b154cc7 303 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 110 303 2.6E-29 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 VAPA_1c11460 a88caf3a38dee7ff3fc676371b154cc7 303 SUPERFAMILY SSF161098 88 283 9.94E-25 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c11460 a88caf3a38dee7ff3fc676371b154cc7 303 Gene3D G3DSA:1.10.3720.10 82 299 5.8E-24 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c07740 a257f4c307ba325400563dbfdd6deb85 284 Gene3D G3DSA:3.40.50.620 3 281 4.2E-75 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold VAPA_1c07740 a257f4c307ba325400563dbfdd6deb85 284 TIGRFAM TIGR00552 nadE: NAD+ synthetase 27 276 5.0E-62 T 12-10-2018 IPR003694 NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.1.5|Reactome: R-HSA-196807 VAPA_1c07740 a257f4c307ba325400563dbfdd6deb85 284 Hamap MF_00193 NH(3)-dependent NAD(+) synthetase [nadE]. 26 278 47.796 T 12-10-2018 IPR022926 NH(3)-dependent NAD(+) synthetase GO:0008795|GO:0009435 KEGG: 00760+6.3.1.5 VAPA_1c07740 a257f4c307ba325400563dbfdd6deb85 284 SUPERFAMILY SSF52402 12 280 2.15E-75 T 12-10-2018 VAPA_1c07740 a257f4c307ba325400563dbfdd6deb85 284 Pfam PF02540 NAD synthase 31 275 2.7E-59 T 12-10-2018 IPR022310 NAD/GMP synthase VAPA_1c28690 d306d6510dfbeafc4cb1a8993e7bf606 157 SUPERFAMILY SSF54637 12 145 8.2E-10 T 12-10-2018 IPR029069 HotDog domain superfamily VAPA_1c28690 d306d6510dfbeafc4cb1a8993e7bf606 157 Gene3D G3DSA:3.10.129.10 1 149 6.7E-8 T 12-10-2018 VAPA_1c09540 cd94f24ccfac8bc4f82bad489efbbb8b 198 Pfam PF02698 DUF218 domain 37 164 9.7E-22 T 12-10-2018 IPR003848 Domain of unknown function DUF218 VAPA_1c19110 006e0ed9c216aa28e88992440f29a80c 123 Gene3D G3DSA:3.10.180.10 1 122 1.6E-26 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase VAPA_1c19110 006e0ed9c216aa28e88992440f29a80c 123 SUPERFAMILY SSF54593 4 121 3.71E-19 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase VAPA_1c19110 006e0ed9c216aa28e88992440f29a80c 123 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 6 117 1.6E-6 T 12-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain VAPA_1c23640 29afc219f27752829f84c8515ff9bb0b 382 Gene3D G3DSA:3.20.20.70 66 336 9.2E-106 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 VAPA_1c23640 29afc219f27752829f84c8515ff9bb0b 382 PIRSF PIRSF006004 2 364 6.5E-145 T 12-10-2018 IPR004383 Ribosomal RNA large subunit methyltransferase RlmN/Cfr GO:0005737|GO:0006364|GO:0008173 VAPA_1c23640 29afc219f27752829f84c8515ff9bb0b 382 SUPERFAMILY SSF102114 100 328 1.96E-13 T 12-10-2018 VAPA_1c23640 29afc219f27752829f84c8515ff9bb0b 382 Gene3D G3DSA:1.10.150.530 3 64 4.9E-24 T 12-10-2018 VAPA_1c23640 29afc219f27752829f84c8515ff9bb0b 382 TIGRFAM TIGR00048 rRNA_mod_RlmN: 23S rRNA (adenine(2503)-C(2))-methyltransferase 3 354 2.9E-131 T 12-10-2018 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 VAPA_1c23640 29afc219f27752829f84c8515ff9bb0b 382 Pfam PF04055 Radical SAM superfamily 107 279 2.7E-15 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 VAPA_1c23640 29afc219f27752829f84c8515ff9bb0b 382 Hamap MF_01849 Dual-specificity RNA methyltransferase RlmN [rlmN]. 3 351 73.789 T 12-10-2018 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 VAPA_1c53610 f40f28a1be33431f0dbfa61bf66786fc 186 SMART SM01322 1 184 1.9E-116 T 12-10-2018 IPR009822 YaeQ VAPA_1c53610 f40f28a1be33431f0dbfa61bf66786fc 186 Pfam PF07152 YaeQ protein 1 181 1.1E-69 T 12-10-2018 IPR009822 YaeQ VAPA_1c53610 f40f28a1be33431f0dbfa61bf66786fc 186 Gene3D G3DSA:3.10.640.10 1 186 6.4E-70 T 12-10-2018 IPR038590 YaeQ superfamily VAPA_1c53610 f40f28a1be33431f0dbfa61bf66786fc 186 PIRSF PIRSF011484 1 186 1.4E-61 T 12-10-2018 IPR009822 YaeQ VAPA_1c53610 f40f28a1be33431f0dbfa61bf66786fc 186 SUPERFAMILY SSF52980 2 186 2.95E-65 T 12-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 VAPA_1c50590 022adeeb9ff91d28707dfed763407096 289 Pfam PF00119 ATP synthase A chain 44 282 1.6E-55 T 12-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 VAPA_1c50590 022adeeb9ff91d28707dfed763407096 289 ProSitePatterns PS00449 ATP synthase a subunit signature. 213 222 - T 12-10-2018 IPR023011 ATP synthase, F0 complex, subunit A, active site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 VAPA_1c50590 022adeeb9ff91d28707dfed763407096 289 Hamap MF_01393 ATP synthase subunit a [atpB]. 10 289 13.814 T 12-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 VAPA_1c50590 022adeeb9ff91d28707dfed763407096 289 TIGRFAM TIGR01131 ATP_synt_6_or_A: ATP synthase F0, A subunit 37 284 3.6E-42 T 12-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 VAPA_1c50590 022adeeb9ff91d28707dfed763407096 289 Gene3D G3DSA:1.20.120.220 94 289 1.1E-52 T 12-10-2018 IPR035908 ATP synthase, F0 complex, subunit A superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 VAPA_1c50590 022adeeb9ff91d28707dfed763407096 289 SUPERFAMILY SSF81336 97 283 1.22E-40 T 12-10-2018 IPR035908 ATP synthase, F0 complex, subunit A superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 VAPA_1c38740 4fdbdf2799ff3574ac45a02762d9e8b3 245 SUPERFAMILY SSF53474 5 230 1.24E-41 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c38740 4fdbdf2799ff3574ac45a02762d9e8b3 245 Gene3D G3DSA:3.40.50.1820 4 235 2.6E-55 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c38740 4fdbdf2799ff3574ac45a02762d9e8b3 245 Pfam PF00975 Thioesterase domain 7 227 5.1E-40 T 12-10-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 VAPA_1c23810 485d428c72cdaf67f56462c0359ce0bc 153 SUPERFAMILY SSF54593 6 145 7.52E-32 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase VAPA_1c23810 485d428c72cdaf67f56462c0359ce0bc 153 Gene3D G3DSA:3.30.720.110 74 142 6.2E-22 T 12-10-2018 VAPA_1c23810 485d428c72cdaf67f56462c0359ce0bc 153 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 4 124 3.4E-11 T 12-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain VAPA_1c23810 485d428c72cdaf67f56462c0359ce0bc 153 Gene3D G3DSA:3.30.720.120 4 68 4.1E-8 T 12-10-2018 VAPA_1c45820 92b3d8afd59993100a9d3b99d2d9068c 145 SUPERFAMILY SSF54593 1 141 2.67E-31 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase VAPA_1c45820 92b3d8afd59993100a9d3b99d2d9068c 145 Gene3D G3DSA:3.10.180.10 7 145 8.7E-42 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase VAPA_1c45820 92b3d8afd59993100a9d3b99d2d9068c 145 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 9 137 1.4E-6 T 12-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain VAPA_2c00630 17b953aeab4592009d0e8ae1a52b0024 369 Gene3D G3DSA:3.40.50.2300 146 272 1.1E-66 T 12-10-2018 VAPA_2c00630 17b953aeab4592009d0e8ae1a52b0024 369 Gene3D G3DSA:3.40.50.2300 35 348 1.1E-66 T 12-10-2018 VAPA_2c00630 17b953aeab4592009d0e8ae1a52b0024 369 Pfam PF13458 Periplasmic binding protein 27 364 1.3E-53 T 12-10-2018 IPR028081 Leucine-binding protein domain VAPA_2c00630 17b953aeab4592009d0e8ae1a52b0024 369 SUPERFAMILY SSF53822 26 366 1.99E-72 T 12-10-2018 IPR028082 Periplasmic binding protein-like I VAPA_1c50950 c000a20325215a85d69c39619fe65729 226 ProSitePatterns PS00474 Ribosomal protein L3 signature. 109 132 - T 12-10-2018 IPR019926 Ribosomal protein L3, conserved site VAPA_1c50950 c000a20325215a85d69c39619fe65729 226 Hamap MF_01325_B 50S ribosomal protein L3 [rplC]. 6 215 36.8 T 12-10-2018 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 VAPA_1c50950 c000a20325215a85d69c39619fe65729 226 Pfam PF00297 Ribosomal protein L3 42 190 6.5E-16 T 12-10-2018 IPR000597 Ribosomal protein L3 GO:0003735|GO:0005622|GO:0005840|GO:0006412 VAPA_1c50950 c000a20325215a85d69c39619fe65729 226 Gene3D G3DSA:2.40.50.620 36 96 1.0E-15 T 12-10-2018 VAPA_1c50950 c000a20325215a85d69c39619fe65729 226 TIGRFAM TIGR03625 L3_bact: 50S ribosomal protein uL3 8 212 4.4E-80 T 12-10-2018 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 VAPA_1c50950 c000a20325215a85d69c39619fe65729 226 SUPERFAMILY SSF50447 6 219 5.65E-74 T 12-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily VAPA_1c50950 c000a20325215a85d69c39619fe65729 226 Gene3D G3DSA:2.40.30.10 129 218 1.1E-14 T 12-10-2018 VAPA_1c04480 e3ba8a4281e8975829bbb43ff83caf99 329 Pfam PF00248 Aldo/keto reductase family 19 319 3.4E-59 T 12-10-2018 IPR023210 NADP-dependent oxidoreductase domain VAPA_1c04480 e3ba8a4281e8975829bbb43ff83caf99 329 Gene3D G3DSA:3.20.20.100 3 328 1.9E-102 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily VAPA_1c04480 e3ba8a4281e8975829bbb43ff83caf99 329 SUPERFAMILY SSF51430 4 324 4.06E-89 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily VAPA_1c21750 2614d4eeb9d74795773d20648ae57c65 145 SUPERFAMILY SSF54909 56 141 3.62E-21 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel VAPA_1c21750 2614d4eeb9d74795773d20648ae57c65 145 Pfam PF13412 Winged helix-turn-helix DNA-binding 2 43 1.6E-12 T 12-10-2018 VAPA_1c21750 2614d4eeb9d74795773d20648ae57c65 145 Gene3D G3DSA:3.30.70.920 49 133 2.6E-25 T 12-10-2018 VAPA_1c21750 2614d4eeb9d74795773d20648ae57c65 145 SMART SM00344 1 105 1.9E-35 T 12-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 VAPA_1c21750 2614d4eeb9d74795773d20648ae57c65 145 Pfam PF01037 Lrp/AsnC ligand binding domain 62 135 1.4E-24 T 12-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain VAPA_1c21750 2614d4eeb9d74795773d20648ae57c65 145 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 12 23 1.0E-9 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 VAPA_1c21750 2614d4eeb9d74795773d20648ae57c65 145 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 23 42 1.0E-9 T 12-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 VAPA_1c21750 2614d4eeb9d74795773d20648ae57c65 145 Gene3D G3DSA:1.10.10.10 1 47 2.4E-16 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c21750 2614d4eeb9d74795773d20648ae57c65 145 SUPERFAMILY SSF46785 2 56 7.96E-15 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c21750 2614d4eeb9d74795773d20648ae57c65 145 ProSitePatterns PS00519 AsnC-type HTH domain signature. 14 40 - T 12-10-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site VAPA_1c19340 cac75f502381e394c47ce12b46ef688a 135 Pfam PF00472 RF-1 domain 6 130 4.7E-25 T 12-10-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 VAPA_1c19340 cac75f502381e394c47ce12b46ef688a 135 SUPERFAMILY SSF75620 6 98 5.89E-13 T 12-10-2018 VAPA_1c19340 cac75f502381e394c47ce12b46ef688a 135 Gene3D G3DSA:3.30.160.20 1 135 2.2E-38 T 12-10-2018 VAPA_1c19340 cac75f502381e394c47ce12b46ef688a 135 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 19 35 - T 12-10-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 VAPA_1c32900 387ba5f53377e50dafea3e78c37a1e0d 220 Pfam PF02397 Bacterial sugar transferase 23 213 3.3E-59 T 12-10-2018 IPR003362 Bacterial sugar transferase VAPA_2c02370 cf094784a72400dcda7d0aaae06dd2c6 592 Pfam PF09423 PhoD-like phosphatase 184 559 3.6E-121 T 12-10-2018 IPR018946 Alkaline phosphatase D-related VAPA_2c02370 cf094784a72400dcda7d0aaae06dd2c6 592 Gene3D G3DSA:2.60.40.380 76 175 9.9E-34 T 12-10-2018 IPR008963 Purple acid phosphatase-like, N-terminal GO:0003993|GO:0046872 VAPA_2c02370 cf094784a72400dcda7d0aaae06dd2c6 592 Gene3D G3DSA:3.60.21.70 176 590 6.9E-124 T 12-10-2018 IPR038607 PhoD-like superfamily VAPA_2c02370 cf094784a72400dcda7d0aaae06dd2c6 592 Pfam PF16655 PhoD-like phosphatase, N-terminal domain 85 173 3.3E-31 T 12-10-2018 IPR032093 Phospholipase D, N-terminal VAPA_2c02370 cf094784a72400dcda7d0aaae06dd2c6 592 SUPERFAMILY SSF56300 183 559 4.75E-29 T 12-10-2018 VAPA_1c50120 6b5b80fbdc398ebaa4437ace5318f2cc 198 SUPERFAMILY SSF55469 15 195 1.31E-42 T 12-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 VAPA_1c50120 6b5b80fbdc398ebaa4437ace5318f2cc 198 Hamap MF_01204 Probable malonic semialdehyde reductase RutE [rutE]. 4 198 46.234 T 12-10-2018 IPR023936 NADH dehydrogenase/NAD(P)H nitroreductase, putative, RutE GO:0016491|GO:0055114 VAPA_1c50120 6b5b80fbdc398ebaa4437ace5318f2cc 198 Gene3D G3DSA:3.40.109.10 5 196 1.9E-27 T 12-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 VAPA_1c50120 6b5b80fbdc398ebaa4437ace5318f2cc 198 Pfam PF00881 Nitroreductase family 19 175 7.8E-17 T 12-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 VAPA_1c18770 7c228a88689b7a6a64241c7230795d14 224 Gene3D G3DSA:3.40.50.1240 1 217 1.8E-33 T 12-10-2018 IPR029033 Histidine phosphatase superfamily VAPA_1c18770 7c228a88689b7a6a64241c7230795d14 224 SMART SM00855 3 167 8.5E-11 T 12-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 VAPA_1c18770 7c228a88689b7a6a64241c7230795d14 224 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 4 207 1.8E-24 T 12-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 VAPA_1c18770 7c228a88689b7a6a64241c7230795d14 224 SUPERFAMILY SSF53254 1 220 5.63E-42 T 12-10-2018 IPR029033 Histidine phosphatase superfamily VAPA_1c04730 2542a90424c9964962912b441678b077 301 SUPERFAMILY SSF161098 94 281 2.88E-27 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c04730 2542a90424c9964962912b441678b077 301 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 117 300 1.6E-30 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 VAPA_1c04730 2542a90424c9964962912b441678b077 301 Gene3D G3DSA:1.10.3720.10 90 296 1.9E-21 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c04730 2542a90424c9964962912b441678b077 301 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 19 70 5.1E-15 T 12-10-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain VAPA_1c29570 61b8a06293ac7aab72c21c9f3e55d978 254 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 9 190 8.4E-4 T 12-10-2018 VAPA_1c29570 61b8a06293ac7aab72c21c9f3e55d978 254 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 146 174 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 VAPA_1c29570 61b8a06293ac7aab72c21c9f3e55d978 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 159 178 4.4E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c29570 61b8a06293ac7aab72c21c9f3e55d978 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 139 147 4.4E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c29570 61b8a06293ac7aab72c21c9f3e55d978 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 4.4E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c29570 61b8a06293ac7aab72c21c9f3e55d978 254 Pfam PF00106 short chain dehydrogenase 10 200 7.0E-51 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c29570 61b8a06293ac7aab72c21c9f3e55d978 254 Gene3D G3DSA:3.40.50.720 9 254 2.7E-67 T 12-10-2018 VAPA_1c29570 61b8a06293ac7aab72c21c9f3e55d978 254 SUPERFAMILY SSF51735 6 233 2.09E-61 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c29570 61b8a06293ac7aab72c21c9f3e55d978 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 180 197 1.6E-22 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c29570 61b8a06293ac7aab72c21c9f3e55d978 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 1.6E-22 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c29570 61b8a06293ac7aab72c21c9f3e55d978 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 159 178 1.6E-22 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c29570 61b8a06293ac7aab72c21c9f3e55d978 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 1.6E-22 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c29570 61b8a06293ac7aab72c21c9f3e55d978 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 133 149 1.6E-22 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c50190 c786006c97ac220f1e5dd95ba1667f03 343 Pfam PF02653 Branched-chain amino acid transport system / permease component 52 323 2.8E-38 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 VAPA_2c01550 b55bacfbb3970bd76456f54fe65f2328 159 Gene3D G3DSA:3.10.180.70 1 159 1.1E-62 T 12-10-2018 VAPA_2c01550 b55bacfbb3970bd76456f54fe65f2328 159 PIRSF PIRSF021700 1 159 1.7E-68 T 12-10-2018 IPR009725 Predicted 3-demethylubiquinone-9 3-methyltransferase VAPA_2c01550 b55bacfbb3970bd76456f54fe65f2328 159 Pfam PF06983 3-demethylubiquinone-9 3-methyltransferase 4 119 5.9E-47 T 12-10-2018 IPR028973 PhnB-like VAPA_2c01550 b55bacfbb3970bd76456f54fe65f2328 159 SUPERFAMILY SSF54593 4 157 4.78E-48 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase VAPA_1c49810 14429e02f8cf4e97e091f3d71c217fe3 378 Pfam PF00437 Type II/IV secretion system protein 113 253 1.5E-36 T 12-10-2018 IPR001482 Type II/IV secretion system protein VAPA_1c49810 14429e02f8cf4e97e091f3d71c217fe3 378 Gene3D G3DSA:3.40.50.300 108 364 3.1E-88 T 12-10-2018 VAPA_1c49810 14429e02f8cf4e97e091f3d71c217fe3 378 SUPERFAMILY SSF52540 8 344 5.32E-68 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c49810 14429e02f8cf4e97e091f3d71c217fe3 378 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 200 214 - T 12-10-2018 IPR001482 Type II/IV secretion system protein VAPA_1c49810 14429e02f8cf4e97e091f3d71c217fe3 378 TIGRFAM TIGR01420 pilT_fam: twitching motility protein 10 351 2.8E-136 T 12-10-2018 IPR006321 Pilus retraction protein PilT GO:0005524 VAPA_1c49810 14429e02f8cf4e97e091f3d71c217fe3 378 Gene3D G3DSA:3.30.450.90 1 107 1.7E-29 T 12-10-2018 VAPA_2c09030 ab2d773bab3f83a62ef14d721b0f4960 139 Pfam PF07883 Cupin domain 56 124 9.2E-15 T 12-10-2018 IPR013096 Cupin 2, conserved barrel VAPA_2c09030 ab2d773bab3f83a62ef14d721b0f4960 139 Gene3D G3DSA:2.60.120.10 25 134 2.2E-18 T 12-10-2018 IPR014710 RmlC-like jelly roll fold VAPA_2c09030 ab2d773bab3f83a62ef14d721b0f4960 139 SUPERFAMILY SSF51182 29 136 7.18E-21 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily VAPA_1c03190 edea1c3c23105e0058d9d1574723906b 400 SUPERFAMILY SSF53901 211 397 5.44E-46 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 VAPA_1c03190 edea1c3c23105e0058d9d1574723906b 400 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 99 240 2.7E-24 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal VAPA_1c03190 edea1c3c23105e0058d9d1574723906b 400 SMART SM00825 Beta-ketoacyl synthase 19 400 4.8E-7 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain VAPA_1c03190 edea1c3c23105e0058d9d1574723906b 400 Gene3D G3DSA:3.40.47.10 251 394 3.2E-39 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 VAPA_1c03190 edea1c3c23105e0058d9d1574723906b 400 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 156 172 - T 12-10-2018 IPR018201 Beta-ketoacyl synthase, active site VAPA_1c03190 edea1c3c23105e0058d9d1574723906b 400 SUPERFAMILY SSF53901 9 239 3.57E-33 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 VAPA_1c03190 edea1c3c23105e0058d9d1574723906b 400 Gene3D G3DSA:3.40.47.10 7 247 8.3E-32 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 VAPA_1c03190 edea1c3c23105e0058d9d1574723906b 400 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 249 356 1.2E-26 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal VAPA_1c11210 862e2c697118e0c65a1d90641c379ea0 748 Gene3D G3DSA:3.40.720.10 322 522 3.4E-48 T 12-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 VAPA_1c11210 862e2c697118e0c65a1d90641c379ea0 748 Gene3D G3DSA:3.40.720.10 35 203 1.5E-29 T 12-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 VAPA_1c11210 862e2c697118e0c65a1d90641c379ea0 748 Pfam PF05506 Domain of unknown function (DUF756) 648 730 3.9E-27 T 12-10-2018 IPR008475 Bacterial phospholipase C, C-terminal domain GO:0004629|GO:0016042 KEGG: 00562+3.1.4.3|KEGG: 00564+3.1.4.3|KEGG: 00565+3.1.4.3|MetaCyc: PWY-7782|MetaCyc: PWY-7783 VAPA_1c11210 862e2c697118e0c65a1d90641c379ea0 748 Pfam PF05506 Domain of unknown function (DUF756) 547 636 9.6E-26 T 12-10-2018 IPR008475 Bacterial phospholipase C, C-terminal domain GO:0004629|GO:0016042 KEGG: 00562+3.1.4.3|KEGG: 00564+3.1.4.3|KEGG: 00565+3.1.4.3|MetaCyc: PWY-7782|MetaCyc: PWY-7783 VAPA_1c11210 862e2c697118e0c65a1d90641c379ea0 748 TIGRFAM TIGR03396 PC_PLC: phospholipase C, phosphocholine-specific 3 744 8.9E-285 T 12-10-2018 IPR017767 Bacterial phospholipase C, phosphocholine-specific GO:0034480 KEGG: 00562+3.1.4.3|KEGG: 00564+3.1.4.3|KEGG: 00565+3.1.4.3|MetaCyc: PWY-7782|MetaCyc: PWY-7783 VAPA_1c11210 862e2c697118e0c65a1d90641c379ea0 748 Pfam PF04185 Phosphoesterase family 46 475 3.2E-100 T 12-10-2018 IPR007312 Phosphoesterase GO:0016788 VAPA_2c08640 782b25db1da1cc7d83460ac72353f937 159 Pfam PF02627 Carboxymuconolactone decarboxylase family 12 93 5.6E-20 T 12-10-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 VAPA_2c08640 782b25db1da1cc7d83460ac72353f937 159 Gene3D G3DSA:1.20.1290.10 1 148 9.6E-48 T 12-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 VAPA_2c08640 782b25db1da1cc7d83460ac72353f937 159 SUPERFAMILY SSF69118 4 145 6.62E-45 T 12-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 VAPA_2c08640 782b25db1da1cc7d83460ac72353f937 159 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 30 78 1.6E-15 T 12-10-2018 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 VAPA_1c46030 0316aae810746d3e1478cee8c5dec2d0 246 Gene3D G3DSA:1.10.10.10 132 243 7.7E-31 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c46030 0316aae810746d3e1478cee8c5dec2d0 246 SMART SM00862 162 238 1.1E-18 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 VAPA_1c46030 0316aae810746d3e1478cee8c5dec2d0 246 Gene3D G3DSA:3.40.50.2300 2 131 3.1E-36 T 12-10-2018 VAPA_1c46030 0316aae810746d3e1478cee8c5dec2d0 246 Pfam PF00486 Transcriptional regulatory protein, C terminal 165 238 3.4E-20 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 VAPA_1c46030 0316aae810746d3e1478cee8c5dec2d0 246 Pfam PF00072 Response regulator receiver domain 9 120 7.8E-28 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_1c46030 0316aae810746d3e1478cee8c5dec2d0 246 SMART SM00448 7 120 3.3E-42 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_1c46030 0316aae810746d3e1478cee8c5dec2d0 246 SUPERFAMILY SSF52172 6 135 4.41E-39 T 12-10-2018 IPR011006 CheY-like superfamily VAPA_1c46030 0316aae810746d3e1478cee8c5dec2d0 246 SUPERFAMILY SSF46894 139 238 2.83E-22 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 VAPA_2c05080 8590af305b4bf9ca582fe8abaaaa8830 133 Gene3D G3DSA:2.150.10.10 2 35 1.4E-5 T 12-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal VAPA_2c05080 8590af305b4bf9ca582fe8abaaaa8830 133 Pfam PF03895 YadA-like membrane anchor domain 73 133 9.2E-22 T 12-10-2018 IPR005594 YadA-like, C-terminal VAPA_2c05080 8590af305b4bf9ca582fe8abaaaa8830 133 Pfam PF05662 Coiled stalk of trimeric autotransporter adhesin 12 49 1.8E-9 T 12-10-2018 IPR008635 Coiled stalk of trimeric autotransporter adhesin GO:0009405|GO:0019867 VAPA_2c05080 8590af305b4bf9ca582fe8abaaaa8830 133 SUPERFAMILY SSF101967 7 32 1.7E-5 T 12-10-2018 VAPA_2c05080 8590af305b4bf9ca582fe8abaaaa8830 133 Gene3D G3DSA:3.30.1300.30 40 133 6.6E-35 T 12-10-2018 VAPA_2c05080 8590af305b4bf9ca582fe8abaaaa8830 133 SUPERFAMILY SSF54523 22 133 8.63E-28 T 12-10-2018 VAPA_1c48940 9936c107924daaa4f85850ac9dc6cc94 326 Gene3D G3DSA:3.30.2010.10 230 321 3.4E-17 T 12-10-2018 VAPA_1c48940 9936c107924daaa4f85850ac9dc6cc94 326 Pfam PF01863 Protein of unknown function DUF45 103 319 9.3E-54 T 12-10-2018 IPR002725 Protein of unknown function DUF45 VAPA_1c02030 33d4e985bffb633abc2bd175ea666fc1 347 SUPERFAMILY SSF82282 14 338 9.42E-97 T 12-10-2018 IPR036589 Homocysteine-binding domain superfamily Reactome: R-HSA-1614635 VAPA_1c02030 33d4e985bffb633abc2bd175ea666fc1 347 Gene3D G3DSA:3.20.20.330 6 340 4.9E-124 T 12-10-2018 IPR036589 Homocysteine-binding domain superfamily Reactome: R-HSA-1614635 VAPA_1c02030 33d4e985bffb633abc2bd175ea666fc1 347 Pfam PF02574 Homocysteine S-methyltransferase 22 329 9.0E-80 T 12-10-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 VAPA_1c02030 33d4e985bffb633abc2bd175ea666fc1 347 PIRSF PIRSF037505 60 344 1.2E-7 T 12-10-2018 IPR017226 Betaine-homocysteine S-methyltransferase, BHMT GO:0005737|GO:0008270|GO:0009086|GO:0047150 Reactome: R-HSA-1614635 VAPA_1c03080 bb49db02559e1a21ef2dc254584f6ec8 439 SUPERFAMILY SSF103473 32 436 1.1E-59 T 12-10-2018 IPR036259 MFS transporter superfamily VAPA_1c03080 bb49db02559e1a21ef2dc254584f6ec8 439 Gene3D G3DSA:1.20.1250.20 29 438 2.7E-57 T 12-10-2018 VAPA_1c03080 bb49db02559e1a21ef2dc254584f6ec8 439 Pfam PF07690 Major Facilitator Superfamily 39 390 5.3E-21 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 VAPA_2c01810 40827ed02e3a16a188c32e6551674af6 287 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 74 283 2.1E-64 T 12-10-2018 IPR011234 Fumarylacetoacetase-like, C-terminal GO:0003824 VAPA_2c01810 40827ed02e3a16a188c32e6551674af6 287 Gene3D G3DSA:3.90.850.10 69 287 7.0E-79 T 12-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 VAPA_2c01810 40827ed02e3a16a188c32e6551674af6 287 SUPERFAMILY SSF56529 63 285 1.57E-75 T 12-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 VAPA_1c13110 b8e58dfa99fb2db74153a9aa42b3cfc3 286 SUPERFAMILY SSF51556 4 268 2.41E-69 T 12-10-2018 IPR032466 Metal-dependent hydrolase VAPA_1c13110 b8e58dfa99fb2db74153a9aa42b3cfc3 286 PIRSF PIRSF005902 1 272 3.9E-62 T 12-10-2018 IPR001130 TatD family GO:0016788 VAPA_1c13110 b8e58dfa99fb2db74153a9aa42b3cfc3 286 ProSitePatterns PS01137 TatD deoxyribonuclease family signature 1. 4 12 - T 12-10-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 VAPA_1c13110 b8e58dfa99fb2db74153a9aa42b3cfc3 286 Pfam PF01026 TatD related DNase 5 268 1.3E-58 T 12-10-2018 IPR001130 TatD family GO:0016788 VAPA_1c13110 b8e58dfa99fb2db74153a9aa42b3cfc3 286 Gene3D G3DSA:3.20.20.140 1 269 1.1E-66 T 12-10-2018 VAPA_1c21790 f6eac835833d2c74b8bebf3c01bcefe5 286 Pfam PF13714 Phosphoenolpyruvate phosphomutase 7 248 9.6E-52 T 12-10-2018 VAPA_1c21790 f6eac835833d2c74b8bebf3c01bcefe5 286 Gene3D G3DSA:3.20.20.60 4 286 1.6E-97 T 12-10-2018 VAPA_1c21790 f6eac835833d2c74b8bebf3c01bcefe5 286 SUPERFAMILY SSF51621 4 286 2.11E-91 T 12-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 VAPA_2c08310 ba3689ea658c94a9658ca309edb0d2a1 221 Gene3D G3DSA:1.10.10.10 1 80 2.6E-5 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c24780 d5251740ca2be7b520575ac7e8efca8d 258 SUPERFAMILY SSF53335 76 220 1.53E-17 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase VAPA_1c24780 d5251740ca2be7b520575ac7e8efca8d 258 Pfam PF08241 Methyltransferase domain 77 123 6.9E-9 T 12-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 VAPA_1c24780 d5251740ca2be7b520575ac7e8efca8d 258 Gene3D G3DSA:3.40.50.150 9 191 1.1E-16 T 12-10-2018 VAPA_1c15240 d7d68914a8cce5f58cd9e3679f61c412 265 SUPERFAMILY SSF46785 29 103 5.3E-22 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c15240 d7d68914a8cce5f58cd9e3679f61c412 265 SMART SM00866 117 259 1.4E-30 T 12-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 VAPA_1c15240 d7d68914a8cce5f58cd9e3679f61c412 265 Gene3D G3DSA:3.40.1410.10 102 264 2.3E-51 T 12-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily VAPA_1c15240 d7d68914a8cce5f58cd9e3679f61c412 265 Pfam PF07702 UTRA domain 125 258 2.9E-33 T 12-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 VAPA_1c15240 d7d68914a8cce5f58cd9e3679f61c412 265 SUPERFAMILY SSF64288 83 263 6.44E-39 T 12-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily VAPA_1c15240 d7d68914a8cce5f58cd9e3679f61c412 265 Pfam PF00392 Bacterial regulatory proteins, gntR family 31 94 9.5E-21 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_1c15240 d7d68914a8cce5f58cd9e3679f61c412 265 SMART SM00345 35 94 3.0E-21 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_1c15240 d7d68914a8cce5f58cd9e3679f61c412 265 Gene3D G3DSA:1.10.10.10 27 95 5.1E-25 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c15240 d7d68914a8cce5f58cd9e3679f61c412 265 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 68 84 6.6E-6 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_1c15240 d7d68914a8cce5f58cd9e3679f61c412 265 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 54 68 6.6E-6 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_1c07910 2f5ec04d3facda336b653bbc3c277098 265 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 259 1.9E-44 T 12-10-2018 VAPA_1c07910 2f5ec04d3facda336b653bbc3c277098 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 181 198 3.6E-31 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c07910 2f5ec04d3facda336b653bbc3c277098 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 225 245 3.6E-31 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c07910 2f5ec04d3facda336b653bbc3c277098 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 87 98 3.6E-31 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c07910 2f5ec04d3facda336b653bbc3c277098 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 134 150 3.6E-31 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c07910 2f5ec04d3facda336b653bbc3c277098 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 3.6E-31 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c07910 2f5ec04d3facda336b653bbc3c277098 265 Gene3D G3DSA:3.40.50.720 2 263 2.1E-67 T 12-10-2018 VAPA_1c07910 2f5ec04d3facda336b653bbc3c277098 265 SUPERFAMILY SSF51735 6 261 9.27E-66 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c30620 94abe4ebb039daf469c0bda451747d6f 241 SUPERFAMILY SSF52540 5 231 4.99E-55 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c30620 94abe4ebb039daf469c0bda451747d6f 241 Gene3D G3DSA:3.40.50.300 2 240 1.3E-57 T 12-10-2018 VAPA_1c30620 94abe4ebb039daf469c0bda451747d6f 241 SMART SM00382 30 216 1.1E-7 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c30620 94abe4ebb039daf469c0bda451747d6f 241 Pfam PF00005 ABC transporter 21 167 4.0E-27 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c30620 94abe4ebb039daf469c0bda451747d6f 241 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_2c11240 30a46cf41274f5b3a8819e51c3d31045 344 Gene3D G3DSA:2.40.160.10 22 344 1.5E-67 T 12-10-2018 IPR023614 Porin domain superfamily VAPA_2c11240 30a46cf41274f5b3a8819e51c3d31045 344 Pfam PF13609 Gram-negative porin 15 324 1.4E-46 T 12-10-2018 VAPA_2c11240 30a46cf41274f5b3a8819e51c3d31045 344 SUPERFAMILY SSF56935 34 344 1.67E-64 T 12-10-2018 VAPA_1c50220 e3f2d9609af7c2f51abaafe9d140171e 324 PRINTS PR00682 Isopenicillin N synthase signature 202 223 6.2E-9 T 12-10-2018 VAPA_1c50220 e3f2d9609af7c2f51abaafe9d140171e 324 PRINTS PR00682 Isopenicillin N synthase signature 303 321 6.2E-9 T 12-10-2018 VAPA_1c50220 e3f2d9609af7c2f51abaafe9d140171e 324 PRINTS PR00682 Isopenicillin N synthase signature 266 284 6.2E-9 T 12-10-2018 VAPA_1c50220 e3f2d9609af7c2f51abaafe9d140171e 324 PRINTS PR00682 Isopenicillin N synthase signature 28 45 6.2E-9 T 12-10-2018 VAPA_1c50220 e3f2d9609af7c2f51abaafe9d140171e 324 SUPERFAMILY SSF51197 3 318 2.13E-90 T 12-10-2018 VAPA_1c50220 e3f2d9609af7c2f51abaafe9d140171e 324 Pfam PF03171 2OG-Fe(II) oxygenase superfamily 182 277 1.9E-23 T 12-10-2018 IPR005123 Oxoglutarate/iron-dependent dioxygenase GO:0016491|GO:0055114 VAPA_1c50220 e3f2d9609af7c2f51abaafe9d140171e 324 Gene3D G3DSA:2.60.120.330 2 322 3.6E-99 T 12-10-2018 IPR027443 Isopenicillin N synthase-like VAPA_1c50220 e3f2d9609af7c2f51abaafe9d140171e 324 Pfam PF14226 non-haem dioxygenase in morphine synthesis N-terminal 5 131 2.3E-20 T 12-10-2018 IPR026992 Non-haem dioxygenase N-terminal domain VAPA_1c26040 123936c428b1a325f08d9440eda417c0 179 TIGRFAM TIGR00079 pept_deformyl: peptide deformylase 4 158 1.8E-33 T 12-10-2018 IPR023635 Peptide deformylase VAPA_1c26040 123936c428b1a325f08d9440eda417c0 179 Pfam PF01327 Polypeptide deformylase 4 159 4.8E-45 T 12-10-2018 IPR023635 Peptide deformylase VAPA_1c26040 123936c428b1a325f08d9440eda417c0 179 Hamap MF_00163 Peptide deformylase [def]. 2 172 26.546 T 12-10-2018 IPR023635 Peptide deformylase VAPA_1c26040 123936c428b1a325f08d9440eda417c0 179 Gene3D G3DSA:3.90.45.10 1 179 2.3E-61 T 12-10-2018 IPR036821 Peptide deformylase superfamily VAPA_1c26040 123936c428b1a325f08d9440eda417c0 179 SUPERFAMILY SSF56420 1 167 7.07E-56 T 12-10-2018 IPR036821 Peptide deformylase superfamily VAPA_1c26040 123936c428b1a325f08d9440eda417c0 179 PIRSF PIRSF004749 1 165 2.1E-44 T 12-10-2018 IPR023635 Peptide deformylase VAPA_1c26040 123936c428b1a325f08d9440eda417c0 179 PRINTS PR01576 Peptide deformylase signature 99 110 2.7E-27 T 12-10-2018 IPR023635 Peptide deformylase VAPA_1c26040 123936c428b1a325f08d9440eda417c0 179 PRINTS PR01576 Peptide deformylase signature 34 63 2.7E-27 T 12-10-2018 IPR023635 Peptide deformylase VAPA_1c26040 123936c428b1a325f08d9440eda417c0 179 PRINTS PR01576 Peptide deformylase signature 111 129 2.7E-27 T 12-10-2018 IPR023635 Peptide deformylase VAPA_1c26040 123936c428b1a325f08d9440eda417c0 179 PRINTS PR01576 Peptide deformylase signature 130 159 2.7E-27 T 12-10-2018 IPR023635 Peptide deformylase VAPA_1c32570 e2ee05ab91a5ae1a8c09495167d8f24d 291 SUPERFAMILY SSF53474 23 289 1.52E-47 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c32570 e2ee05ab91a5ae1a8c09495167d8f24d 291 Pfam PF12697 Alpha/beta hydrolase family 49 283 1.8E-19 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 VAPA_1c32570 e2ee05ab91a5ae1a8c09495167d8f24d 291 Gene3D G3DSA:3.40.50.1820 35 290 2.6E-47 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c01320 09658ecefa8dc1a707aa9cb97834b3bc 192 SUPERFAMILY SSF52141 1 188 1.46E-55 T 12-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 VAPA_1c01320 09658ecefa8dc1a707aa9cb97834b3bc 192 Gene3D G3DSA:3.40.470.10 1 191 1.4E-66 T 12-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 VAPA_1c01320 09658ecefa8dc1a707aa9cb97834b3bc 192 Pfam PF03167 Uracil DNA glycosylase superfamily 29 178 3.2E-25 T 12-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 VAPA_1c01320 09658ecefa8dc1a707aa9cb97834b3bc 192 SMART SM00986 25 182 1.2E-25 T 12-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 VAPA_1c01320 09658ecefa8dc1a707aa9cb97834b3bc 192 SMART SM00987 25 182 1.2E-25 T 12-10-2018 VAPA_1c06710 ac6bad4f5cd271066e471bc510f66ebe 210 SUPERFAMILY SSF51735 1 194 1.32E-41 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c06710 ac6bad4f5cd271066e471bc510f66ebe 210 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 3 91 1.0E-16 T 12-10-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal VAPA_1c06710 ac6bad4f5cd271066e471bc510f66ebe 210 Gene3D G3DSA:3.40.50.720 1 203 1.2E-56 T 12-10-2018 VAPA_1c21220 27acc6ecf97f7a75b6e320d943a26571 294 SUPERFAMILY SSF53335 28 222 5.83E-36 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase VAPA_1c21220 27acc6ecf97f7a75b6e320d943a26571 294 Gene3D G3DSA:3.40.50.150 3 257 6.8E-39 T 12-10-2018 VAPA_1c21220 27acc6ecf97f7a75b6e320d943a26571 294 Pfam PF13649 Methyltransferase domain 54 143 2.1E-20 T 12-10-2018 VAPA_1c44620 bcf5fe4604f7457d178a8302157db35a 542 TIGRFAM TIGR01539 portal_lambda: phage portal protein, lambda family 35 503 1.1E-79 T 12-10-2018 IPR006429 Phage portal protein, lambda family GO:0005198|GO:0019068 VAPA_1c44620 bcf5fe4604f7457d178a8302157db35a 542 Pfam PF05136 Phage portal protein, lambda family 37 403 1.6E-104 T 12-10-2018 IPR006429 Phage portal protein, lambda family GO:0005198|GO:0019068 VAPA_1c36320 ee1163ca76f4a2774d03ebf224e17b41 309 Gene3D G3DSA:1.10.3720.10 113 301 2.3E-23 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c36320 ee1163ca76f4a2774d03ebf224e17b41 309 SUPERFAMILY SSF161098 110 293 6.67E-28 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c36320 ee1163ca76f4a2774d03ebf224e17b41 309 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 133 296 2.4E-21 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 VAPA_1c36320 ee1163ca76f4a2774d03ebf224e17b41 309 TIGRFAM TIGR01183 ntrB: nitrate ABC transporter, permease protein 99 292 9.2E-74 T 12-10-2018 IPR005889 Nitrate transport permease GO:0015112|GO:0015706|GO:0016021 VAPA_1c22600 611535d349ac27f169f07862f7fbf5d6 331 SUPERFAMILY SSF53850 122 286 2.72E-10 T 12-10-2018 VAPA_1c22600 611535d349ac27f169f07862f7fbf5d6 331 PIRSF PIRSF017082 5 330 6.1E-71 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c22600 611535d349ac27f169f07862f7fbf5d6 331 Gene3D G3DSA:3.40.190.150 36 321 1.4E-99 T 12-10-2018 VAPA_1c22600 611535d349ac27f169f07862f7fbf5d6 331 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 56 327 1.8E-71 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c22600 611535d349ac27f169f07862f7fbf5d6 331 Gene3D G3DSA:3.40.190.10 134 256 1.4E-99 T 12-10-2018 VAPA_1c23030 4428673372c1308eaae29b6fb96f149e 212 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 49 72 1.9E-7 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 VAPA_1c23030 4428673372c1308eaae29b6fb96f149e 212 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 28 41 1.9E-7 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 VAPA_1c23030 4428673372c1308eaae29b6fb96f149e 212 Gene3D G3DSA:1.10.357.10 24 207 2.3E-35 T 12-10-2018 VAPA_1c23030 4428673372c1308eaae29b6fb96f149e 212 Pfam PF00440 Bacterial regulatory proteins, tetR family 28 74 9.2E-13 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 VAPA_1c23030 4428673372c1308eaae29b6fb96f149e 212 SUPERFAMILY SSF46689 13 91 4.99E-18 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 VAPA_1c03400 21f861deff1a386a4172d5df51ed068e 267 SUPERFAMILY SSF56219 2 264 3.01E-70 T 12-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily VAPA_1c03400 21f861deff1a386a4172d5df51ed068e 267 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 6 256 5.4E-16 T 12-10-2018 IPR005135 Endonuclease/exonuclease/phosphatase VAPA_1c03400 21f861deff1a386a4172d5df51ed068e 267 TIGRFAM TIGR00633 xth: exodeoxyribonuclease III (xth) 3 263 1.5E-70 T 12-10-2018 IPR004808 AP endonuclease 1 GO:0004518|GO:0006281 VAPA_1c03400 21f861deff1a386a4172d5df51ed068e 267 TIGRFAM TIGR00195 exoDNase_III: exodeoxyribonuclease III 3 261 1.5E-65 T 12-10-2018 VAPA_1c03400 21f861deff1a386a4172d5df51ed068e 267 Gene3D G3DSA:3.60.10.10 1 265 1.5E-74 T 12-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily VAPA_1c37110 7f06570ff5052d9e2e1e1f06e8def699 114 Pfam PF05437 Branched-chain amino acid transport protein (AzlD) 9 108 1.6E-21 T 12-10-2018 IPR008407 Branched-chain amino acid transport, AzlD VAPA_1c45960 9ec8b42dfad70e1ae5148a7eaae32e46 112 Gene3D G3DSA:3.10.180.10 1 112 3.7E-17 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase VAPA_1c45960 9ec8b42dfad70e1ae5148a7eaae32e46 112 SUPERFAMILY SSF54593 5 110 1.75E-15 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase VAPA_1c15060 4f06a85b9272d0a816b2b47df7bd7823 290 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 165 183 8.2E-37 T 12-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 VAPA_1c15060 4f06a85b9272d0a816b2b47df7bd7823 290 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 231 242 8.2E-37 T 12-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 VAPA_1c15060 4f06a85b9272d0a816b2b47df7bd7823 290 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 202 219 8.2E-37 T 12-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 VAPA_1c15060 4f06a85b9272d0a816b2b47df7bd7823 290 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 253 262 8.2E-37 T 12-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 VAPA_1c15060 4f06a85b9272d0a816b2b47df7bd7823 290 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 131 145 8.2E-37 T 12-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 VAPA_1c15060 4f06a85b9272d0a816b2b47df7bd7823 290 Hamap MF_01395 Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, chloroplastic [accD]. 1 283 37.13 T 12-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 VAPA_1c15060 4f06a85b9272d0a816b2b47df7bd7823 290 Gene3D G3DSA:3.90.226.10 27 288 7.5E-81 T 12-10-2018 VAPA_1c15060 4f06a85b9272d0a816b2b47df7bd7823 290 SUPERFAMILY SSF52096 27 285 1.09E-82 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily VAPA_1c15060 4f06a85b9272d0a816b2b47df7bd7823 290 Pfam PF01039 Carboxyl transferase domain 101 241 1.9E-15 T 12-10-2018 IPR034733 Acetyl-CoA carboxylase MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722|Reactome: R-HSA-196780 VAPA_1c15060 4f06a85b9272d0a816b2b47df7bd7823 290 TIGRFAM TIGR00515 accD: acetyl-CoA carboxylase, carboxyl transferase, beta subunit 1 285 5.3E-118 T 12-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 VAPA_1c31750 e094a6bb2e4e659e37386fc94585e792 169 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 20 42 6.3E-8 T 12-10-2018 IPR012902 Prokaryotic N-terminal methylation site VAPA_1c31750 e094a6bb2e4e659e37386fc94585e792 169 Pfam PF07963 Prokaryotic N-terminal methylation motif 20 42 2.2E-7 T 12-10-2018 IPR012902 Prokaryotic N-terminal methylation site VAPA_1c31750 e094a6bb2e4e659e37386fc94585e792 169 SUPERFAMILY SSF54523 22 114 8.63E-18 T 12-10-2018 VAPA_1c31750 e094a6bb2e4e659e37386fc94585e792 169 Gene3D G3DSA:3.30.700.10 22 159 5.7E-15 T 12-10-2018 VAPA_1c31750 e094a6bb2e4e659e37386fc94585e792 169 Pfam PF12019 Type II transport protein GspH 59 161 3.4E-11 T 12-10-2018 IPR022346 General secretion pathway, GspH GO:0008565|GO:0015627|GO:0015628 VAPA_1c42410 d36d30bb96bd6fdecc4915552a723324 557 SUPERFAMILY SSF52091 456 549 1.51E-14 T 12-10-2018 IPR036513 STAS domain superfamily VAPA_1c42410 d36d30bb96bd6fdecc4915552a723324 557 Pfam PF00916 Sulfate permease family 26 399 7.5E-84 T 12-10-2018 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 VAPA_1c42410 d36d30bb96bd6fdecc4915552a723324 557 Gene3D G3DSA:3.30.750.24 448 556 1.3E-17 T 12-10-2018 IPR036513 STAS domain superfamily VAPA_1c42410 d36d30bb96bd6fdecc4915552a723324 557 Pfam PF01740 STAS domain 458 548 1.3E-10 T 12-10-2018 IPR002645 STAS domain VAPA_1c33830 1b7f3ce57bfe34a411a17989a81a49ac 141 SUPERFAMILY SSF54534 29 139 7.07E-45 T 12-10-2018 VAPA_1c33830 1b7f3ce57bfe34a411a17989a81a49ac 141 Gene3D G3DSA:3.10.50.40 19 141 8.5E-49 T 12-10-2018 VAPA_1c33830 1b7f3ce57bfe34a411a17989a81a49ac 141 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 49 136 1.4E-28 T 12-10-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain VAPA_1c34470 c594bd9a18e4678eeef00f268ac198fc 719 Pfam PF00149 Calcineurin-like phosphoesterase 92 318 1.9E-5 T 12-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 VAPA_1c34470 c594bd9a18e4678eeef00f268ac198fc 719 SUPERFAMILY SSF49899 504 710 3.69E-15 T 12-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily VAPA_1c34470 c594bd9a18e4678eeef00f268ac198fc 719 Gene3D G3DSA:3.60.21.10 96 348 1.1E-13 T 12-10-2018 IPR029052 Metallo-dependent phosphatase-like VAPA_1c34470 c594bd9a18e4678eeef00f268ac198fc 719 SUPERFAMILY SSF56300 89 328 1.22E-23 T 12-10-2018 VAPA_1c34470 c594bd9a18e4678eeef00f268ac198fc 719 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 548 709 3.7E-12 T 12-10-2018 VAPA_1c34470 c594bd9a18e4678eeef00f268ac198fc 719 Gene3D G3DSA:2.60.120.200 540 717 3.9E-15 T 12-10-2018 VAPA_1c35660 04549494aa17281450ae4e78f838a8c9 324 Gene3D G3DSA:3.40.190.10 126 249 5.6E-107 T 12-10-2018 VAPA_1c35660 04549494aa17281450ae4e78f838a8c9 324 PIRSF PIRSF017082 1 323 2.0E-79 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c35660 04549494aa17281450ae4e78f838a8c9 324 SUPERFAMILY SSF53850 114 286 3.16E-12 T 12-10-2018 VAPA_1c35660 04549494aa17281450ae4e78f838a8c9 324 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 47 320 2.8E-73 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c35660 04549494aa17281450ae4e78f838a8c9 324 Gene3D G3DSA:3.40.190.150 28 314 5.6E-107 T 12-10-2018 VAPA_2c04670 39c091523b0dc955f852317f2fa101b2 485 Pfam PF00501 AMP-binding enzyme 217 302 5.4E-7 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 VAPA_2c04670 39c091523b0dc955f852317f2fa101b2 485 SUPERFAMILY SSF56801 133 390 6.28E-16 T 12-10-2018 VAPA_2c04670 39c091523b0dc955f852317f2fa101b2 485 Gene3D G3DSA:3.40.50.12780 40 381 7.7E-57 T 12-10-2018 VAPA_1c23720 40a64bca581fc416fc7a309eb4df0719 81 SUPERFAMILY SSF50182 8 70 7.51E-24 T 12-10-2018 IPR010920 LSM domain superfamily VAPA_1c23720 40a64bca581fc416fc7a309eb4df0719 81 TIGRFAM TIGR02383 Hfq: RNA chaperone Hfq 8 65 7.1E-29 T 12-10-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 VAPA_1c23720 40a64bca581fc416fc7a309eb4df0719 81 Gene3D G3DSA:2.30.30.100 1 79 2.2E-33 T 12-10-2018 VAPA_1c23720 40a64bca581fc416fc7a309eb4df0719 81 Pfam PF17209 Hfq protein 8 69 4.4E-31 T 12-10-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 VAPA_1c23720 40a64bca581fc416fc7a309eb4df0719 81 Hamap MF_00436 RNA-binding protein Hfq [hfq]. 4 65 27.778 T 12-10-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 VAPA_1c10060 aea313b7ee0ba89e26cc8d9bd73dd6b1 147 Pfam PF07382 Histone H1-like nucleoprotein HC2 3 145 3.8E-16 T 12-10-2018 IPR009970 Histone H1-like nucleoprotein HC2 GO:0003677|GO:0030261 VAPA_1c42740 ac57af1ae8d98eaa84a6cc462b6e560d 243 Pfam PF01227 GTP cyclohydrolase I 60 239 2.1E-52 T 12-10-2018 IPR020602 GTP cyclohydrolase I domain KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 VAPA_1c42740 ac57af1ae8d98eaa84a6cc462b6e560d 243 Gene3D G3DSA:3.30.1130.10 106 242 5.6E-41 T 12-10-2018 VAPA_1c42740 ac57af1ae8d98eaa84a6cc462b6e560d 243 Gene3D G3DSA:1.10.286.10 27 103 4.6E-7 T 12-10-2018 VAPA_1c42740 ac57af1ae8d98eaa84a6cc462b6e560d 243 SUPERFAMILY SSF55620 23 240 2.52E-65 T 12-10-2018 VAPA_1c00220 38fc1fdd46b7563df2e84b1e05023125 691 TIGRFAM TIGR02595 PEP_exosort: PEP-CTERM protein-sorting domain 658 681 0.0038 T 12-10-2018 IPR013424 PEP-CTERM protein-sorting domain VAPA_1c00220 38fc1fdd46b7563df2e84b1e05023125 691 SUPERFAMILY SSF53300 322 487 1.04E-26 T 12-10-2018 IPR036465 von Willebrand factor A-like domain superfamily VAPA_1c00220 38fc1fdd46b7563df2e84b1e05023125 691 SMART SM00327 322 485 9.0E-21 T 12-10-2018 IPR002035 von Willebrand factor, type A VAPA_1c00220 38fc1fdd46b7563df2e84b1e05023125 691 Pfam PF13768 von Willebrand factor type A domain 326 472 7.1E-21 T 12-10-2018 IPR002035 von Willebrand factor, type A VAPA_1c00220 38fc1fdd46b7563df2e84b1e05023125 691 Gene3D G3DSA:3.40.50.410 323 492 2.2E-28 T 12-10-2018 IPR036465 von Willebrand factor A-like domain superfamily VAPA_1c00220 38fc1fdd46b7563df2e84b1e05023125 691 SMART SM00609 51 176 1.2E-10 T 12-10-2018 IPR013694 VIT domain VAPA_1c00220 38fc1fdd46b7563df2e84b1e05023125 691 Pfam PF08487 Vault protein inter-alpha-trypsin domain 64 174 6.8E-33 T 12-10-2018 IPR013694 VIT domain VAPA_2c02120 6383293464fbce1386ba80831eda79bc 1624 Pfam PF03527 RHS protein 1375 1409 1.7E-17 T 12-10-2018 IPR001826 RHS protein VAPA_2c02120 6383293464fbce1386ba80831eda79bc 1624 Gene3D G3DSA:3.90.930.1 579 769 1.8E-10 T 12-10-2018 VAPA_2c02120 6383293464fbce1386ba80831eda79bc 1624 Gene3D G3DSA:3.90.930.1 770 926 1.2E-8 T 12-10-2018 VAPA_2c02120 6383293464fbce1386ba80831eda79bc 1624 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 863 904 4.0E-7 T 12-10-2018 IPR006530 YD repeat VAPA_2c02120 6383293464fbce1386ba80831eda79bc 1624 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 681 721 5.5E-7 T 12-10-2018 IPR006530 YD repeat VAPA_2c02120 6383293464fbce1386ba80831eda79bc 1624 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1127 1165 0.0013 T 12-10-2018 IPR006530 YD repeat VAPA_2c02120 6383293464fbce1386ba80831eda79bc 1624 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 722 763 2.8E-9 T 12-10-2018 IPR006530 YD repeat VAPA_2c02120 6383293464fbce1386ba80831eda79bc 1624 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 743 782 2.3E-10 T 12-10-2018 IPR006530 YD repeat VAPA_2c02120 6383293464fbce1386ba80831eda79bc 1624 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 787 825 2.0E-9 T 12-10-2018 IPR006530 YD repeat VAPA_2c02120 6383293464fbce1386ba80831eda79bc 1624 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 905 945 4.4E-4 T 12-10-2018 IPR006530 YD repeat VAPA_2c02120 6383293464fbce1386ba80831eda79bc 1624 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 988 1018 0.0019 T 12-10-2018 IPR006530 YD repeat VAPA_2c02120 6383293464fbce1386ba80831eda79bc 1624 TIGRFAM TIGR03696 Rhs_assc_core: RHS repeat-associated core domain 1402 1483 2.5E-28 T 12-10-2018 IPR022385 Rhs repeat-associated core GO:0097264 VAPA_2c02120 6383293464fbce1386ba80831eda79bc 1624 Pfam PF05593 RHS Repeat 785 821 2.5E-7 T 12-10-2018 IPR031325 RHS repeat VAPA_2c02120 6383293464fbce1386ba80831eda79bc 1624 Pfam PF05593 RHS Repeat 743 779 3.6E-10 T 12-10-2018 IPR031325 RHS repeat VAPA_2c02120 6383293464fbce1386ba80831eda79bc 1624 Pfam PF05593 RHS Repeat 864 900 4.1E-6 T 12-10-2018 IPR031325 RHS repeat VAPA_2c02120 6383293464fbce1386ba80831eda79bc 1624 Pfam PF05593 RHS Repeat 701 737 2.4E-9 T 12-10-2018 IPR031325 RHS repeat VAPA_2c08620 b30808638d18882faa960f8fb66c8693 470 Pfam PF13546 DDE superfamily endonuclease 14 287 1.6E-94 T 12-10-2018 IPR038721 Transposase IS701-like, DDE domain VAPA_2c08620 b30808638d18882faa960f8fb66c8693 470 SUPERFAMILY SSF53098 17 394 4.63E-29 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily VAPA_1c05750 3d8a5954cdd9f25027174af945b23e21 231 TIGRFAM TIGR01163 rpe: ribulose-phosphate 3-epimerase 7 222 1.6E-88 T 12-10-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 VAPA_1c05750 3d8a5954cdd9f25027174af945b23e21 231 ProSitePatterns PS01086 Ribulose-phosphate 3-epimerase family signature 2. 142 164 - T 12-10-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 VAPA_1c05750 3d8a5954cdd9f25027174af945b23e21 231 SUPERFAMILY SSF51366 5 223 1.99E-70 T 12-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 VAPA_1c05750 3d8a5954cdd9f25027174af945b23e21 231 Pfam PF00834 Ribulose-phosphate 3 epimerase family 7 209 1.3E-81 T 12-10-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 VAPA_1c05750 3d8a5954cdd9f25027174af945b23e21 231 ProSitePatterns PS01085 Ribulose-phosphate 3-epimerase family signature 1. 34 48 - T 12-10-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 VAPA_1c05750 3d8a5954cdd9f25027174af945b23e21 231 Gene3D G3DSA:3.20.20.70 5 227 1.7E-78 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 VAPA_1c05750 3d8a5954cdd9f25027174af945b23e21 231 PIRSF PIRSF001461 1 229 4.2E-97 T 12-10-2018 IPR026019 Ribulose-phosphate 3-epimerase GO:0004750|GO:0006098 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 VAPA_1c22550 873a79ed9c7c930c319c141b3a0b1a21 193 Pfam PF00866 Ring hydroxylating beta subunit 35 185 3.4E-36 T 12-10-2018 IPR000391 Ring-hydroxylating dioxygenase beta subunit GO:0006725|GO:0055114 VAPA_1c22550 873a79ed9c7c930c319c141b3a0b1a21 193 Gene3D G3DSA:3.10.450.50 12 193 1.1E-56 T 12-10-2018 VAPA_1c22550 873a79ed9c7c930c319c141b3a0b1a21 193 SUPERFAMILY SSF54427 22 193 2.68E-38 T 12-10-2018 IPR032710 NTF2-like domain superfamily VAPA_1c04280 8bde9c42ca348171fc6c25324b5f52e2 404 SUPERFAMILY SSF53822 34 396 1.91E-68 T 12-10-2018 IPR028082 Periplasmic binding protein-like I VAPA_1c04280 8bde9c42ca348171fc6c25324b5f52e2 404 Gene3D G3DSA:3.40.50.2300 42 358 1.9E-63 T 12-10-2018 VAPA_1c04280 8bde9c42ca348171fc6c25324b5f52e2 404 Gene3D G3DSA:3.40.50.2300 154 289 1.9E-63 T 12-10-2018 VAPA_1c04280 8bde9c42ca348171fc6c25324b5f52e2 404 Pfam PF13458 Periplasmic binding protein 34 379 3.0E-61 T 12-10-2018 IPR028081 Leucine-binding protein domain VAPA_1c04280 8bde9c42ca348171fc6c25324b5f52e2 404 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 57 73 1.8E-6 T 12-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 VAPA_1c04280 8bde9c42ca348171fc6c25324b5f52e2 404 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 76 94 1.8E-6 T 12-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 VAPA_1c04280 8bde9c42ca348171fc6c25324b5f52e2 404 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 35 51 1.8E-6 T 12-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 VAPA_1c04280 8bde9c42ca348171fc6c25324b5f52e2 404 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 293 306 1.8E-6 T 12-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 VAPA_1c05720 7d8f370f7f6d66ea5b48fdec66e1f16b 423 Gene3D G3DSA:1.20.1530.20 26 407 6.8E-19 T 12-10-2018 IPR038770 Sodium/solute symporter superfamily VAPA_1c05720 7d8f370f7f6d66ea5b48fdec66e1f16b 423 Pfam PF00999 Sodium/hydrogen exchanger family 31 396 1.6E-16 T 12-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 VAPA_1c22230 396bf149fb80b63d1a2f81362fd8381f 322 Gene3D G3DSA:1.10.10.10 3 89 4.7E-23 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c22230 396bf149fb80b63d1a2f81362fd8381f 322 SUPERFAMILY SSF53850 90 295 1.61E-38 T 12-10-2018 VAPA_1c22230 396bf149fb80b63d1a2f81362fd8381f 322 SUPERFAMILY SSF46785 3 111 6.9E-21 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c22230 396bf149fb80b63d1a2f81362fd8381f 322 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 2.2E-18 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c22230 396bf149fb80b63d1a2f81362fd8381f 322 Gene3D G3DSA:3.40.190.290 91 291 2.4E-54 T 12-10-2018 VAPA_1c22230 396bf149fb80b63d1a2f81362fd8381f 322 Pfam PF03466 LysR substrate binding domain 89 292 9.6E-33 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_2c06590 5687dfe0065357061551288a866b9e95 215 PRINTS PR00111 Alpha/beta hydrolase fold signature 82 95 1.2E-6 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 VAPA_2c06590 5687dfe0065357061551288a866b9e95 215 PRINTS PR00111 Alpha/beta hydrolase fold signature 96 109 1.2E-6 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 VAPA_2c06590 5687dfe0065357061551288a866b9e95 215 PRINTS PR00111 Alpha/beta hydrolase fold signature 39 54 1.2E-6 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 VAPA_2c06590 5687dfe0065357061551288a866b9e95 215 Gene3D G3DSA:3.40.50.1820 7 213 1.6E-44 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_2c06590 5687dfe0065357061551288a866b9e95 215 Pfam PF00561 alpha/beta hydrolase fold 14 136 2.4E-20 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 VAPA_2c06590 5687dfe0065357061551288a866b9e95 215 SUPERFAMILY SSF53474 5 189 6.76E-37 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c30970 8eeb666982ed25c879c19f619dcb5d03 139 Pfam PF00101 Ribulose bisphosphate carboxylase, small chain 5 103 4.0E-39 T 12-10-2018 IPR000894 Ribulose bisphosphate carboxylase small chain, domain KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 VAPA_1c30970 8eeb666982ed25c879c19f619dcb5d03 139 SUPERFAMILY SSF55239 1 138 4.06E-53 T 12-10-2018 IPR036385 Ribulose bisphosphate carboxylase, small subunit superfamily KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 VAPA_1c30970 8eeb666982ed25c879c19f619dcb5d03 139 SMART SM00961 4 103 1.2E-51 T 12-10-2018 IPR000894 Ribulose bisphosphate carboxylase small chain, domain KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 VAPA_1c30970 8eeb666982ed25c879c19f619dcb5d03 139 Gene3D G3DSA:3.30.190.10 1 139 3.0E-56 T 12-10-2018 IPR036385 Ribulose bisphosphate carboxylase, small subunit superfamily KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 VAPA_1c22770 888813c365ba0ff12424705d7a6f95fa 317 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 22 78 1.1E-17 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c22770 888813c365ba0ff12424705d7a6f95fa 317 SUPERFAMILY SSF46785 16 96 1.02E-18 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c22770 888813c365ba0ff12424705d7a6f95fa 317 SUPERFAMILY SSF53850 101 308 7.06E-38 T 12-10-2018 VAPA_1c22770 888813c365ba0ff12424705d7a6f95fa 317 Gene3D G3DSA:3.40.190.10 181 280 7.4E-60 T 12-10-2018 VAPA_1c22770 888813c365ba0ff12424705d7a6f95fa 317 Pfam PF03466 LysR substrate binding domain 106 304 6.1E-23 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_1c22770 888813c365ba0ff12424705d7a6f95fa 317 Gene3D G3DSA:1.10.10.10 11 98 1.1E-26 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c22770 888813c365ba0ff12424705d7a6f95fa 317 Gene3D G3DSA:3.40.190.10 101 304 7.4E-60 T 12-10-2018 VAPA_1c22770 888813c365ba0ff12424705d7a6f95fa 317 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 46 56 5.2E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c22770 888813c365ba0ff12424705d7a6f95fa 317 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 35 46 5.2E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c22770 888813c365ba0ff12424705d7a6f95fa 317 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 56 67 5.2E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c20230 6d1f9f7d3fc5065b3bcb074292549e52 185 Pfam PF06821 Serine hydrolase 6 180 5.3E-43 T 12-10-2018 IPR010662 Putative hydrolase RBBP9/YdeN GO:0016787 VAPA_1c20230 6d1f9f7d3fc5065b3bcb074292549e52 185 Gene3D G3DSA:3.40.50.1820 1 184 8.5E-46 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c20230 6d1f9f7d3fc5065b3bcb074292549e52 185 SUPERFAMILY SSF53474 4 176 3.29E-26 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c19090 94e64ddf3a68d3a90951277023fccbc7 149 Pfam PF14526 Integron-associated effector binding protein 8 138 8.4E-19 T 12-10-2018 IPR029441 Integron-associated effector binding protein VAPA_1c19090 94e64ddf3a68d3a90951277023fccbc7 149 Gene3D G3DSA:3.20.80.10 1 149 1.4E-37 T 12-10-2018 IPR011256 Regulatory factor, effector binding domain superfamily VAPA_1c19090 94e64ddf3a68d3a90951277023fccbc7 149 SMART SM00871 1 149 1.4E-22 T 12-10-2018 IPR010499 Bacterial transcription activator, effector binding VAPA_1c19090 94e64ddf3a68d3a90951277023fccbc7 149 SUPERFAMILY SSF55136 1 137 3.4E-14 T 12-10-2018 IPR011256 Regulatory factor, effector binding domain superfamily VAPA_2c11270 3966ebd734d3ef7d6840efd08c647c05 295 SUPERFAMILY SSF51556 24 293 8.32E-81 T 12-10-2018 IPR032466 Metal-dependent hydrolase VAPA_2c11270 3966ebd734d3ef7d6840efd08c647c05 295 Gene3D G3DSA:3.20.20.140 6 295 2.5E-88 T 12-10-2018 VAPA_2c11270 3966ebd734d3ef7d6840efd08c647c05 295 Pfam PF04909 Amidohydrolase 29 293 8.2E-51 T 12-10-2018 IPR006680 Amidohydrolase-related GO:0016787 VAPA_1c27770 eb4a6afa81636a0c6c930ad3a6bd0189 301 Pfam PF00135 Carboxylesterase family 64 175 1.6E-18 T 12-10-2018 IPR002018 Carboxylesterase, type B VAPA_1c27770 eb4a6afa81636a0c6c930ad3a6bd0189 301 SUPERFAMILY SSF53474 38 296 1.51E-43 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c27770 eb4a6afa81636a0c6c930ad3a6bd0189 301 Gene3D G3DSA:3.40.50.1820 38 293 3.0E-49 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c27770 eb4a6afa81636a0c6c930ad3a6bd0189 301 ProSitePatterns PS00122 Carboxylesterases type-B serine active site. 146 161 - T 12-10-2018 IPR019826 Carboxylesterase type B, active site VAPA_1c06050 faa3d6df77b2b3a28e2c67906c232953 382 TIGRFAM TIGR03347 VI_chp_1: type VI secretion protein, VC_A0111 family 45 351 1.0E-91 T 12-10-2018 IPR010732 Type VI secretion, TssG-like VAPA_1c06050 faa3d6df77b2b3a28e2c67906c232953 382 Pfam PF06996 Type VI secretion, TssG 45 351 1.0E-92 T 12-10-2018 IPR010732 Type VI secretion, TssG-like VAPA_1c14670 48d23989e436937926013372260dafed 308 Gene3D G3DSA:3.40.190.10 106 205 5.8E-84 T 12-10-2018 VAPA_1c14670 48d23989e436937926013372260dafed 308 PRINTS PR00151 Porphobilinogen deaminase signature 79 98 6.4E-45 T 12-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 VAPA_1c14670 48d23989e436937926013372260dafed 308 PRINTS PR00151 Porphobilinogen deaminase signature 127 144 6.4E-45 T 12-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 VAPA_1c14670 48d23989e436937926013372260dafed 308 PRINTS PR00151 Porphobilinogen deaminase signature 233 250 6.4E-45 T 12-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 VAPA_1c14670 48d23989e436937926013372260dafed 308 PRINTS PR00151 Porphobilinogen deaminase signature 48 68 6.4E-45 T 12-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 VAPA_1c14670 48d23989e436937926013372260dafed 308 PRINTS PR00151 Porphobilinogen deaminase signature 146 163 6.4E-45 T 12-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 VAPA_1c14670 48d23989e436937926013372260dafed 308 SUPERFAMILY SSF53850 10 221 3.74E-83 T 12-10-2018 VAPA_1c14670 48d23989e436937926013372260dafed 308 TIGRFAM TIGR00212 hemC: hydroxymethylbilane synthase 11 302 4.3E-105 T 12-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 VAPA_1c14670 48d23989e436937926013372260dafed 308 Gene3D G3DSA:3.40.190.10 11 212 5.8E-84 T 12-10-2018 VAPA_1c14670 48d23989e436937926013372260dafed 308 Pfam PF03900 Porphobilinogen deaminase, C-terminal domain 229 302 1.1E-9 T 12-10-2018 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 VAPA_1c14670 48d23989e436937926013372260dafed 308 PIRSF PIRSF001438 5 308 4.4E-112 T 12-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 VAPA_1c14670 48d23989e436937926013372260dafed 308 Gene3D G3DSA:3.30.160.40 224 308 3.7E-13 T 12-10-2018 IPR036803 Porphobilinogen deaminase, C-terminal domain superfamily GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 VAPA_1c14670 48d23989e436937926013372260dafed 308 SUPERFAMILY SSF54782 224 307 5.23E-13 T 12-10-2018 IPR036803 Porphobilinogen deaminase, C-terminal domain superfamily GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 VAPA_1c14670 48d23989e436937926013372260dafed 308 Pfam PF01379 Porphobilinogen deaminase, dipyromethane cofactor binding domain 11 215 1.5E-80 T 12-10-2018 IPR022417 Porphobilinogen deaminase, N-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 VAPA_1c14670 48d23989e436937926013372260dafed 308 Hamap MF_00260 Porphobilinogen deaminase [hemC]. 10 305 37.054 T 12-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 VAPA_1c42890 348ed08a6f92854e6bf77b561d8a7a6c 436 Gene3D G3DSA:3.40.190.10 144 421 1.3E-131 T 12-10-2018 VAPA_1c42890 348ed08a6f92854e6bf77b561d8a7a6c 436 Pfam PF13416 Bacterial extracellular solute-binding protein 43 366 1.1E-37 T 12-10-2018 IPR006059 Bacterial extracellular solute-binding protein VAPA_1c42890 348ed08a6f92854e6bf77b561d8a7a6c 436 SUPERFAMILY SSF53850 20 424 3.15E-73 T 12-10-2018 VAPA_1c42890 348ed08a6f92854e6bf77b561d8a7a6c 436 Gene3D G3DSA:3.40.190.10 28 381 1.3E-131 T 12-10-2018 VAPA_1c39000 d6b1d03083e5210a5de2fccdf23fff2f 213 ProSitePatterns PS00141 Eukaryotic and viral aspartyl proteases active site. 118 129 - T 12-10-2018 IPR001969 Aspartic peptidase, active site GO:0004190|GO:0006508 VAPA_1c39000 d6b1d03083e5210a5de2fccdf23fff2f 213 TIGRFAM TIGR02281 clan_AA_DTGA: clan AA aspartic protease, TIGR02281 family 95 210 7.2E-33 T 12-10-2018 IPR011969 Clan AA aspartic peptidase, C-terminal VAPA_1c39000 d6b1d03083e5210a5de2fccdf23fff2f 213 Pfam PF13975 gag-polyprotein putative aspartyl protease 108 197 1.4E-23 T 12-10-2018 VAPA_1c39000 d6b1d03083e5210a5de2fccdf23fff2f 213 Gene3D G3DSA:2.40.70.10 90 212 7.6E-33 T 12-10-2018 IPR021109 Aspartic peptidase domain superfamily VAPA_1c39000 d6b1d03083e5210a5de2fccdf23fff2f 213 SUPERFAMILY SSF50630 97 201 5.63E-20 T 12-10-2018 IPR021109 Aspartic peptidase domain superfamily VAPA_1c15930 28ffe15278d53161850687286a631536 381 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 48 64 1.5E-6 T 12-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 VAPA_1c15930 28ffe15278d53161850687286a631536 381 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 249 267 1.5E-6 T 12-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 VAPA_1c15930 28ffe15278d53161850687286a631536 381 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 26 42 1.5E-6 T 12-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 VAPA_1c15930 28ffe15278d53161850687286a631536 381 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 86 96 1.5E-6 T 12-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 VAPA_1c15930 28ffe15278d53161850687286a631536 381 Pfam PF13458 Periplasmic binding protein 26 375 2.5E-54 T 12-10-2018 IPR028081 Leucine-binding protein domain VAPA_1c15930 28ffe15278d53161850687286a631536 381 SUPERFAMILY SSF53822 25 380 2.57E-72 T 12-10-2018 IPR028082 Periplasmic binding protein-like I VAPA_1c15930 28ffe15278d53161850687286a631536 381 Gene3D G3DSA:3.40.50.2300 27 365 1.2E-101 T 12-10-2018 VAPA_1c15930 28ffe15278d53161850687286a631536 381 Gene3D G3DSA:3.40.50.2300 140 376 1.2E-101 T 12-10-2018 VAPA_1c26910 327bbb94720c601c98ff41198c8d4565 378 Gene3D G3DSA:3.40.50.1970 2 183 7.1E-53 T 12-10-2018 VAPA_1c26910 327bbb94720c601c98ff41198c8d4565 378 ProSitePatterns PS00913 Iron-containing alcohol dehydrogenases signature 1. 172 200 - T 12-10-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 VAPA_1c26910 327bbb94720c601c98ff41198c8d4565 378 Gene3D G3DSA:1.20.1090.10 185 378 8.0E-50 T 12-10-2018 VAPA_1c26910 327bbb94720c601c98ff41198c8d4565 378 SUPERFAMILY SSF56796 4 376 8.5E-111 T 12-10-2018 VAPA_1c26910 327bbb94720c601c98ff41198c8d4565 378 Pfam PF00465 Iron-containing alcohol dehydrogenase 8 369 8.5E-106 T 12-10-2018 IPR001670 Alcohol dehydrogenase, iron-type/glycerol dehydrogenase GldA GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 VAPA_1c03260 87b855af02f4df3da928bbd649484f93 276 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 100 266 6.9E-20 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 VAPA_1c03260 87b855af02f4df3da928bbd649484f93 276 Gene3D G3DSA:1.10.3720.10 77 272 1.3E-19 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c03260 87b855af02f4df3da928bbd649484f93 276 SUPERFAMILY SSF161098 77 260 9.81E-26 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c54610 8f3b12718aa92063fa8c10c76dbb9045 96 SUPERFAMILY SSF54909 1 83 1.37E-16 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel VAPA_1c54610 8f3b12718aa92063fa8c10c76dbb9045 96 Pfam PF03795 YCII-related domain 1 81 8.4E-14 T 12-10-2018 IPR005545 YCII-related VAPA_1c25490 c640b1593abab100897b00daa3c2f43a 131 Pfam PF06073 Bacterial protein of unknown function (DUF934) 23 127 6.4E-37 T 12-10-2018 IPR008318 Uncharacterised conserved protein UCP030820 VAPA_1c25490 c640b1593abab100897b00daa3c2f43a 131 PIRSF PIRSF030820 8 131 8.7E-33 T 12-10-2018 IPR008318 Uncharacterised conserved protein UCP030820 VAPA_1c51620 9100dde7ca56280a93ae2c57213ca7d5 328 PIRSF PIRSF017082 1 327 3.6E-87 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c51620 9100dde7ca56280a93ae2c57213ca7d5 328 Gene3D G3DSA:3.40.190.10 129 252 1.0E-116 T 12-10-2018 VAPA_1c51620 9100dde7ca56280a93ae2c57213ca7d5 328 Gene3D G3DSA:3.40.190.150 31 318 1.0E-116 T 12-10-2018 VAPA_1c51620 9100dde7ca56280a93ae2c57213ca7d5 328 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 50 324 8.2E-94 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c51620 9100dde7ca56280a93ae2c57213ca7d5 328 SUPERFAMILY SSF53850 114 289 5.98E-13 T 12-10-2018 VAPA_1c39310 2921bd4d8d13e4d200e109eeea9d1547 93 SMART SM00858 11 89 0.0034 T 12-10-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 VAPA_1c39310 2921bd4d8d13e4d200e109eeea9d1547 93 Gene3D G3DSA:3.90.1210.30 3 92 2.4E-22 T 12-10-2018 VAPA_1c49710 c4946d7e8bd1940653ac5cd2607f7b8f 163 Gene3D G3DSA:1.10.10.10 11 147 7.2E-28 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c49710 c4946d7e8bd1940653ac5cd2607f7b8f 163 Pfam PF01047 MarR family 42 95 4.3E-11 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 VAPA_1c49710 c4946d7e8bd1940653ac5cd2607f7b8f 163 SMART SM00347 31 131 8.5E-16 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 VAPA_1c49710 c4946d7e8bd1940653ac5cd2607f7b8f 163 SUPERFAMILY SSF46785 18 149 7.52E-24 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c49710 c4946d7e8bd1940653ac5cd2607f7b8f 163 ProSitePatterns PS01117 MarR-type HTH domain signature. 70 104 - T 12-10-2018 IPR023187 Transcriptional regulator MarR-type, conserved site VAPA_1c39260 65b4ca1e74c209a5501e67f52d0b3128 282 SUPERFAMILY SSF54862 68 267 2.62E-71 T 12-10-2018 VAPA_1c39260 65b4ca1e74c209a5501e67f52d0b3128 282 Pfam PF13247 4Fe-4S dicluster domain 132 233 9.4E-25 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain VAPA_1c39260 65b4ca1e74c209a5501e67f52d0b3128 282 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 172 183 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site VAPA_1c39260 65b4ca1e74c209a5501e67f52d0b3128 282 Gene3D G3DSA:3.30.70.20 63 282 7.4E-68 T 12-10-2018 VAPA_1c39260 65b4ca1e74c209a5501e67f52d0b3128 282 Pfam PF12800 4Fe-4S binding domain 77 91 0.041 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain VAPA_1c38440 6caf9580e406e9a28137a7f9402331a6 183 SUPERFAMILY SSF55068 5 173 1.11E-74 T 12-10-2018 IPR036509 Peptide methionine sulphoxide reductase MsrA superfamily GO:0008113|GO:0055114 Reactome: R-HSA-5676934 VAPA_1c38440 6caf9580e406e9a28137a7f9402331a6 183 Hamap MF_01401 Peptide methionine sulfoxide reductase MsrA [msrA]. 8 167 37.007 T 12-10-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 VAPA_1c38440 6caf9580e406e9a28137a7f9402331a6 183 Pfam PF01625 Peptide methionine sulfoxide reductase 10 162 2.0E-66 T 12-10-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 VAPA_1c38440 6caf9580e406e9a28137a7f9402331a6 183 Gene3D G3DSA:3.30.1060.10 1 172 2.3E-71 T 12-10-2018 IPR036509 Peptide methionine sulphoxide reductase MsrA superfamily GO:0008113|GO:0055114 Reactome: R-HSA-5676934 VAPA_1c38440 6caf9580e406e9a28137a7f9402331a6 183 TIGRFAM TIGR00401 msrA: peptide-methionine (S)-S-oxide reductase 9 162 1.9E-60 T 12-10-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 VAPA_2c12290 69ac6391f24ed7a1ac4f48825e95fe74 364 Gene3D G3DSA:3.30.390.10 17 125 3.5E-111 T 12-10-2018 IPR029017 Enolase-like, N-terminal VAPA_2c12290 69ac6391f24ed7a1ac4f48825e95fe74 364 SMART SM00922 151 247 2.8E-20 T 12-10-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal VAPA_2c12290 69ac6391f24ed7a1ac4f48825e95fe74 364 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 13 133 1.2E-21 T 12-10-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain VAPA_2c12290 69ac6391f24ed7a1ac4f48825e95fe74 364 Gene3D G3DSA:3.20.20.120 126 352 3.5E-111 T 12-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily VAPA_2c12290 69ac6391f24ed7a1ac4f48825e95fe74 364 SUPERFAMILY SSF54826 11 137 7.84E-24 T 12-10-2018 VAPA_2c12290 69ac6391f24ed7a1ac4f48825e95fe74 364 ProSitePatterns PS00908 Mandelate racemase / muconate lactonizing enzyme family signature 1. 108 133 - T 12-10-2018 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 VAPA_2c12290 69ac6391f24ed7a1ac4f48825e95fe74 364 Pfam PF13378 Enolase C-terminal domain-like 156 357 1.2E-51 T 12-10-2018 IPR029065 Enolase C-terminal domain-like VAPA_2c12290 69ac6391f24ed7a1ac4f48825e95fe74 364 SUPERFAMILY SSF51604 121 363 2.75E-65 T 12-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily VAPA_2c12290 69ac6391f24ed7a1ac4f48825e95fe74 364 ProSitePatterns PS00909 Mandelate racemase / muconate lactonizing enzyme family signature 2. 197 228 - T 12-10-2018 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 VAPA_1c17930 740d13e27a309f8c3694b2a1729f0699 287 Gene3D G3DSA:3.30.530.90 93 280 1.8E-9 T 12-10-2018 VAPA_1c17930 740d13e27a309f8c3694b2a1729f0699 287 SUPERFAMILY SSF55961 66 280 9.01E-25 T 12-10-2018 VAPA_2c00010 ada15b9aebe2cc99aaef5083151d6854 262 SUPERFAMILY SSF52540 1 250 1.78E-36 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_2c00010 ada15b9aebe2cc99aaef5083151d6854 262 Pfam PF13614 AAA domain 3 172 2.5E-26 T 12-10-2018 IPR025669 AAA domain VAPA_2c00010 ada15b9aebe2cc99aaef5083151d6854 262 Gene3D G3DSA:3.40.50.300 1 250 7.3E-48 T 12-10-2018 VAPA_2c09800 4f41bd1eef8416650a6a7c6fe4138085 389 SUPERFAMILY SSF56645 8 241 5.76E-77 T 12-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 VAPA_2c09800 4f41bd1eef8416650a6a7c6fe4138085 389 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 337 356 - T 12-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 VAPA_2c09800 4f41bd1eef8416650a6a7c6fe4138085 389 Gene3D G3DSA:1.20.140.10 235 379 1.2E-47 T 12-10-2018 VAPA_2c09800 4f41bd1eef8416650a6a7c6fe4138085 389 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 9 117 3.8E-27 T 12-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 VAPA_2c09800 4f41bd1eef8416650a6a7c6fe4138085 389 Gene3D G3DSA:1.10.540.10 5 118 5.0E-27 T 12-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 VAPA_2c09800 4f41bd1eef8416650a6a7c6fe4138085 389 Gene3D G3DSA:2.40.110.10 120 234 1.7E-43 T 12-10-2018 VAPA_2c09800 4f41bd1eef8416650a6a7c6fe4138085 389 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 121 217 2.9E-28 T 12-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 VAPA_2c09800 4f41bd1eef8416650a6a7c6fe4138085 389 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 230 378 8.1E-44 T 12-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 VAPA_2c09800 4f41bd1eef8416650a6a7c6fe4138085 389 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 123 135 - T 12-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 VAPA_2c09800 4f41bd1eef8416650a6a7c6fe4138085 389 PIRSF PIRSF016578 3 82 7.3E-6 T 12-10-2018 VAPA_2c09800 4f41bd1eef8416650a6a7c6fe4138085 389 PIRSF PIRSF016578 125 383 2.3E-10 T 12-10-2018 VAPA_2c09800 4f41bd1eef8416650a6a7c6fe4138085 389 SUPERFAMILY SSF47203 229 380 3.22E-51 T 12-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 VAPA_1c20870 15248b7bd19a5a02b2260b996744699e 313 SUPERFAMILY SSF53850 100 308 9.77E-34 T 12-10-2018 VAPA_1c20870 15248b7bd19a5a02b2260b996744699e 313 Gene3D G3DSA:3.40.190.10 177 279 2.5E-38 T 12-10-2018 VAPA_1c20870 15248b7bd19a5a02b2260b996744699e 313 SUPERFAMILY SSF46785 12 120 4.35E-19 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c20870 15248b7bd19a5a02b2260b996744699e 313 Gene3D G3DSA:3.40.190.10 105 295 2.5E-38 T 12-10-2018 VAPA_1c20870 15248b7bd19a5a02b2260b996744699e 313 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 50 61 3.4E-7 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c20870 15248b7bd19a5a02b2260b996744699e 313 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 50 3.4E-7 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c20870 15248b7bd19a5a02b2260b996744699e 313 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 40 3.4E-7 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c20870 15248b7bd19a5a02b2260b996744699e 313 Gene3D G3DSA:1.10.10.10 11 99 6.0E-22 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c20870 15248b7bd19a5a02b2260b996744699e 313 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 14 72 1.4E-16 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c20870 15248b7bd19a5a02b2260b996744699e 313 Pfam PF03466 LysR substrate binding domain 98 307 7.2E-33 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_1c21100 b8cea3908a1bebbc4af5e73d46c2c415 683 Hamap MF_02124 Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase [glgE]. 22 671 45.45 T 12-10-2018 IPR026585 Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase GO:0016757 KEGG: 00500+2.4.99.16|MetaCyc: PWY-7900 VAPA_1c21100 b8cea3908a1bebbc4af5e73d46c2c415 683 SUPERFAMILY SSF51011 580 662 1.98E-6 T 12-10-2018 VAPA_1c21100 b8cea3908a1bebbc4af5e73d46c2c415 683 Gene3D G3DSA:3.20.20.80 213 578 3.1E-154 T 12-10-2018 VAPA_1c21100 b8cea3908a1bebbc4af5e73d46c2c415 683 Gene3D G3DSA:1.20.58.280 116 197 9.6E-48 T 12-10-2018 VAPA_1c21100 b8cea3908a1bebbc4af5e73d46c2c415 683 Gene3D G3DSA:2.60.40.1180 580 680 3.5E-30 T 12-10-2018 IPR013780 Glycosyl hydrolase, all-beta VAPA_1c21100 b8cea3908a1bebbc4af5e73d46c2c415 683 SUPERFAMILY SSF51445 201 575 6.21E-76 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily VAPA_1c21100 b8cea3908a1bebbc4af5e73d46c2c415 683 Pfam PF11896 Domain of unknown function (DUF3416) 25 212 1.8E-48 T 12-10-2018 IPR021828 Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase, domain N/S GO:0004553 KEGG: 00500+2.4.99.16|MetaCyc: PWY-7900 VAPA_1c21100 b8cea3908a1bebbc4af5e73d46c2c415 683 SMART SM00642 218 568 1.1E-4 T 12-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 VAPA_1c21100 b8cea3908a1bebbc4af5e73d46c2c415 683 Gene3D G3DSA:2.60.40.10 25 199 9.6E-48 T 12-10-2018 IPR013783 Immunoglobulin-like fold VAPA_1c36530 e1c3e32d42efccad4e04866ee0dcb8a7 156 Gene3D G3DSA:3.90.79.10 7 132 6.5E-19 T 12-10-2018 VAPA_1c36530 e1c3e32d42efccad4e04866ee0dcb8a7 156 PRINTS PR00502 NUDIX hydrolase family signature 36 50 1.5E-5 T 12-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 VAPA_1c36530 e1c3e32d42efccad4e04866ee0dcb8a7 156 PRINTS PR00502 NUDIX hydrolase family signature 50 65 1.5E-5 T 12-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 VAPA_1c36530 e1c3e32d42efccad4e04866ee0dcb8a7 156 SUPERFAMILY SSF55811 11 127 4.47E-20 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 VAPA_1c36530 e1c3e32d42efccad4e04866ee0dcb8a7 156 ProSitePatterns PS00893 Nudix box signature. 41 62 - T 12-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 VAPA_1c36530 e1c3e32d42efccad4e04866ee0dcb8a7 156 Pfam PF00293 NUDIX domain 14 116 2.0E-14 T 12-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 VAPA_2c04590 45e7ef4b638dba500165ff60993aca4e 406 Gene3D G3DSA:3.50.50.60 6 342 1.7E-81 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_2c04590 45e7ef4b638dba500165ff60993aca4e 406 TIGRFAM TIGR01988 Ubi-OHases: ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family 6 394 1.5E-102 T 12-10-2018 IPR010971 Ubiquinone biosynthesis hydroxylase UbiH/COQ6 GO:0006744|GO:0016709|GO:0050660|GO:0055114 Reactome: R-HSA-2142789 VAPA_2c04590 45e7ef4b638dba500165ff60993aca4e 406 SUPERFAMILY SSF51905 5 387 3.82E-48 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_2c04590 45e7ef4b638dba500165ff60993aca4e 406 Gene3D G3DSA:3.30.9.50 80 274 1.7E-81 T 12-10-2018 VAPA_2c04590 45e7ef4b638dba500165ff60993aca4e 406 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 300 316 3.3E-11 T 12-10-2018 VAPA_2c04590 45e7ef4b638dba500165ff60993aca4e 406 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 285 300 3.3E-11 T 12-10-2018 VAPA_2c04590 45e7ef4b638dba500165ff60993aca4e 406 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 6 28 3.3E-11 T 12-10-2018 VAPA_2c04590 45e7ef4b638dba500165ff60993aca4e 406 Pfam PF01494 FAD binding domain 6 325 5.2E-23 T 12-10-2018 IPR002938 FAD-binding domain GO:0071949 VAPA_1c23490 ef4df3a3fe44d86fd6b16e256f5110a2 200 Gene3D G3DSA:3.40.50.850 2 200 1.6E-49 T 12-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 VAPA_1c23490 ef4df3a3fe44d86fd6b16e256f5110a2 200 Pfam PF00857 Isochorismatase family 9 177 1.8E-22 T 12-10-2018 IPR000868 Isochorismatase-like GO:0003824 VAPA_1c23490 ef4df3a3fe44d86fd6b16e256f5110a2 200 SUPERFAMILY SSF52499 2 200 5.89E-39 T 12-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 VAPA_1c53620 5a253fd5a850e9820f438fb8efb302c2 101 Pfam PF09413 Putative prokaryotic signal transducing protein 1 67 4.9E-7 T 12-10-2018 IPR018551 Domain of unknown function DUF2007 VAPA_1c51040 1e29985a17efb2eb4d56e1cfc05c8990 210 Pfam PF00561 alpha/beta hydrolase fold 48 140 3.6E-7 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 VAPA_1c51040 1e29985a17efb2eb4d56e1cfc05c8990 210 SUPERFAMILY SSF53474 3 206 5.0E-38 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c51040 1e29985a17efb2eb4d56e1cfc05c8990 210 Gene3D G3DSA:3.40.50.1820 1 209 1.8E-47 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_2c01300 8edbc48072a253bd9e8d5cf9d3892af8 317 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 37 312 2.0E-22 T 12-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 VAPA_2c01300 8edbc48072a253bd9e8d5cf9d3892af8 317 Gene3D G3DSA:3.40.50.720 21 309 6.7E-97 T 12-10-2018 VAPA_2c01300 8edbc48072a253bd9e8d5cf9d3892af8 317 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 151 178 - T 12-10-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 VAPA_2c01300 8edbc48072a253bd9e8d5cf9d3892af8 317 Gene3D G3DSA:3.40.50.720 101 287 6.7E-97 T 12-10-2018 VAPA_2c01300 8edbc48072a253bd9e8d5cf9d3892af8 317 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 109 284 3.8E-39 T 12-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 VAPA_2c01300 8edbc48072a253bd9e8d5cf9d3892af8 317 SUPERFAMILY SSF51735 101 285 2.32E-42 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_2c01300 8edbc48072a253bd9e8d5cf9d3892af8 317 SUPERFAMILY SSF52283 1 134 1.02E-30 T 12-10-2018 VAPA_1c18590 1e487aea4ec04aad90b789cb06d3144c 470 Pfam PF16980 Putative citrate transport 30 469 6.0E-194 T 12-10-2018 IPR031566 Putative citrate transporter VAPA_2c12450 bd55e020bcb726e43566598f6d7f72ae 281 Pfam PF05988 Bacterial protein of unknown function (DUF899) 32 251 5.2E-80 T 12-10-2018 IPR010296 Protein of unknown function DUF899, thioredoxin-like VAPA_2c12450 bd55e020bcb726e43566598f6d7f72ae 281 SUPERFAMILY SSF52833 112 205 9.74E-5 T 12-10-2018 IPR036249 Thioredoxin-like superfamily VAPA_1c01210 cec706f36d54ad2331c2d1ad4f7499c4 358 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 54 290 8.9E-23 T 12-10-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0030288|GO:0055085 VAPA_1c01210 cec706f36d54ad2331c2d1ad4f7499c4 358 Gene3D G3DSA:3.40.190.170 31 340 1.0E-53 T 12-10-2018 IPR038404 TRAP transporter solute receptor DctP superfamily VAPA_1c43990 450b54ad32f68d0fb4d7afbd4174ef5f 100 ProDom PD002319 SUBUNIT GAMMA HYDROLASE UREASE UREA AMIDOHYDROLASE UREASE ALPHA GAMMA/BETA METAL-BINDING 9 99 4.0E-44 T 12-10-2018 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 VAPA_1c43990 450b54ad32f68d0fb4d7afbd4174ef5f 100 TIGRFAM TIGR00193 urease_gam: urease, gamma subunit 1 99 1.6E-52 T 12-10-2018 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 VAPA_1c43990 450b54ad32f68d0fb4d7afbd4174ef5f 100 Gene3D G3DSA:3.30.280.10 1 100 3.4E-48 T 12-10-2018 IPR036463 Urease, gamma subunit superfamily GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 VAPA_1c43990 450b54ad32f68d0fb4d7afbd4174ef5f 100 Pfam PF00547 Urease, gamma subunit 1 99 5.2E-48 T 12-10-2018 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 VAPA_1c43990 450b54ad32f68d0fb4d7afbd4174ef5f 100 PIRSF PIRSF001223 1 100 1.1E-51 T 12-10-2018 IPR012010 Urease, gamma subunit GO:0009039|GO:0019627 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 VAPA_1c43990 450b54ad32f68d0fb4d7afbd4174ef5f 100 SUPERFAMILY SSF54111 1 99 2.75E-46 T 12-10-2018 IPR036463 Urease, gamma subunit superfamily GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 VAPA_1c43990 450b54ad32f68d0fb4d7afbd4174ef5f 100 Hamap MF_00739 Urease subunit gamma [ureA]. 1 100 35.156 T 12-10-2018 IPR012010 Urease, gamma subunit GO:0009039|GO:0019627 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 VAPA_2c03880 9e048720e3d6538e7ee91dd5823af4f2 437 SUPERFAMILY SSF111369 144 349 1.44E-10 T 12-10-2018 VAPA_2c03880 9e048720e3d6538e7ee91dd5823af4f2 437 Gene3D G3DSA:2.40.30.170 72 351 7.5E-65 T 12-10-2018 VAPA_2c03880 9e048720e3d6538e7ee91dd5823af4f2 437 Gene3D G3DSA:2.40.420.20 68 409 7.5E-65 T 12-10-2018 VAPA_2c03880 9e048720e3d6538e7ee91dd5823af4f2 437 Gene3D G3DSA:1.10.287.470 117 240 7.5E-65 T 12-10-2018 VAPA_2c03880 9e048720e3d6538e7ee91dd5823af4f2 437 SUPERFAMILY SSF111369 75 144 4.05E-10 T 12-10-2018 VAPA_2c03880 9e048720e3d6538e7ee91dd5823af4f2 437 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 216 424 4.1E-37 T 12-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 VAPA_2c03880 9e048720e3d6538e7ee91dd5823af4f2 437 Gene3D G3DSA:2.40.50.100 83 275 7.5E-65 T 12-10-2018 VAPA_2c03880 9e048720e3d6538e7ee91dd5823af4f2 437 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 75 344 7.4E-22 T 12-10-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain VAPA_1c07900 ed696ba808f2fcc6f8d73c404bb82cf1 301 Gene3D G3DSA:3.40.190.10 165 266 6.2E-64 T 12-10-2018 VAPA_1c07900 ed696ba808f2fcc6f8d73c404bb82cf1 301 Gene3D G3DSA:1.10.10.10 4 91 3.0E-20 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c07900 ed696ba808f2fcc6f8d73c404bb82cf1 301 SUPERFAMILY SSF53850 91 295 2.17E-43 T 12-10-2018 VAPA_1c07900 ed696ba808f2fcc6f8d73c404bb82cf1 301 Gene3D G3DSA:3.40.190.10 94 291 6.2E-64 T 12-10-2018 VAPA_1c07900 ed696ba808f2fcc6f8d73c404bb82cf1 301 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 65 6.8E-17 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c07900 ed696ba808f2fcc6f8d73c404bb82cf1 301 Pfam PF03466 LysR substrate binding domain 90 292 1.8E-44 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_1c07900 ed696ba808f2fcc6f8d73c404bb82cf1 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 21 32 4.3E-5 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c07900 ed696ba808f2fcc6f8d73c404bb82cf1 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 53 4.3E-5 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c07900 ed696ba808f2fcc6f8d73c404bb82cf1 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 32 42 4.3E-5 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c07900 ed696ba808f2fcc6f8d73c404bb82cf1 301 SUPERFAMILY SSF46785 5 114 5.45E-21 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_2c02840 b78098cea39eb2e5a38bd6a00a9f7fa8 226 Pfam PF05683 Fumarase C-terminus 13 191 1.4E-23 T 12-10-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 VAPA_2c02840 b78098cea39eb2e5a38bd6a00a9f7fa8 226 Gene3D G3DSA:3.20.130.10 2 191 4.6E-53 T 12-10-2018 IPR036660 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain superfamily GO:0016836 VAPA_2c02840 b78098cea39eb2e5a38bd6a00a9f7fa8 226 SUPERFAMILY SSF117457 12 189 1.29E-43 T 12-10-2018 IPR036660 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain superfamily GO:0016836 VAPA_1c48450 47e14281c4ef9ab517c98472726eceba 324 PIRSF PIRSF017082 1 323 3.1E-82 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c48450 47e14281c4ef9ab517c98472726eceba 324 SUPERFAMILY SSF53850 108 289 6.21E-16 T 12-10-2018 VAPA_1c48450 47e14281c4ef9ab517c98472726eceba 324 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 51 320 7.3E-92 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c48450 47e14281c4ef9ab517c98472726eceba 324 Gene3D G3DSA:3.40.190.150 31 308 1.6E-90 T 12-10-2018 VAPA_1c48450 47e14281c4ef9ab517c98472726eceba 324 Gene3D G3DSA:3.40.190.10 127 248 1.6E-90 T 12-10-2018 VAPA_1c42990 5d3c1b04c6381e9aed90cb342495e261 243 Pfam PF04542 Sigma-70 region 2 13 85 9.2E-17 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 VAPA_1c42990 5d3c1b04c6381e9aed90cb342495e261 243 SUPERFAMILY SSF88659 170 241 5.23E-17 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like VAPA_1c42990 5d3c1b04c6381e9aed90cb342495e261 243 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 11 239 7.1E-32 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 VAPA_1c42990 5d3c1b04c6381e9aed90cb342495e261 243 TIGRFAM TIGR02479 FliA_WhiG: RNA polymerase sigma factor, FliA/WhiG family 13 240 1.9E-81 T 12-10-2018 IPR012845 RNA polymerase sigma factor, FliA/WhiG GO:0003677|GO:0003899|GO:0006352|GO:0006355|GO:0016987 VAPA_1c42990 5d3c1b04c6381e9aed90cb342495e261 243 Gene3D G3DSA:1.10.1740.10 2 82 6.8E-29 T 12-10-2018 VAPA_1c42990 5d3c1b04c6381e9aed90cb342495e261 243 SUPERFAMILY SSF88659 87 153 4.36E-12 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like VAPA_1c42990 5d3c1b04c6381e9aed90cb342495e261 243 Hamap MF_00962 RNA polymerase sigma factor FliA [fliA]. 2 242 62.793 T 12-10-2018 IPR028617 RNA polymerase sigma factor FliA GO:0003677|GO:0003899|GO:0006352|GO:0006355|GO:0016987 VAPA_1c42990 5d3c1b04c6381e9aed90cb342495e261 243 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 209 235 - T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 VAPA_1c42990 5d3c1b04c6381e9aed90cb342495e261 243 SUPERFAMILY SSF88946 3 85 4.45E-23 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 VAPA_1c42990 5d3c1b04c6381e9aed90cb342495e261 243 Pfam PF04539 Sigma-70 region 3 94 151 1.5E-8 T 12-10-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003700|GO:0006352|GO:0006355 VAPA_1c42990 5d3c1b04c6381e9aed90cb342495e261 243 Pfam PF04545 Sigma-70, region 4 188 237 1.0E-14 T 12-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 VAPA_1c42990 5d3c1b04c6381e9aed90cb342495e261 243 Gene3D G3DSA:1.20.140.160 84 242 4.8E-42 T 12-10-2018 VAPA_1c42990 5d3c1b04c6381e9aed90cb342495e261 243 PIRSF PIRSF000770 2 243 1.8E-42 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 VAPA_1c42990 5d3c1b04c6381e9aed90cb342495e261 243 PRINTS PR00046 Major sigma-70 factor signature 224 235 8.3E-10 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 VAPA_1c42990 5d3c1b04c6381e9aed90cb342495e261 243 PRINTS PR00046 Major sigma-70 factor signature 209 224 8.3E-10 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 VAPA_1c42990 5d3c1b04c6381e9aed90cb342495e261 243 PRINTS PR00046 Major sigma-70 factor signature 40 53 8.3E-10 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 VAPA_1c42990 5d3c1b04c6381e9aed90cb342495e261 243 PRINTS PR00046 Major sigma-70 factor signature 192 204 8.3E-10 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 VAPA_1c09690 6d0a341cfadc5bf4807036c4dc03d01d 392 ProSitePatterns PS01347 MraY family signature 1. 71 83 - T 12-10-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 VAPA_1c09690 6d0a341cfadc5bf4807036c4dc03d01d 392 Pfam PF10555 Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 71 81 7.3E-5 T 12-10-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 VAPA_1c09690 6d0a341cfadc5bf4807036c4dc03d01d 392 TIGRFAM TIGR00445 mraY: phospho-N-acetylmuramoyl-pentapeptide-transferase 41 392 1.8E-118 T 12-10-2018 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 VAPA_1c09690 6d0a341cfadc5bf4807036c4dc03d01d 392 ProSitePatterns PS01348 MraY family signature 2. 215 226 - T 12-10-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 VAPA_1c09690 6d0a341cfadc5bf4807036c4dc03d01d 392 Hamap MF_00038 Phospho-N-acetylmuramoyl-pentapeptide-transferase [mraY]. 28 390 23.342 T 12-10-2018 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 VAPA_1c09690 6d0a341cfadc5bf4807036c4dc03d01d 392 Pfam PF00953 Glycosyl transferase family 4 102 310 4.6E-35 T 12-10-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-4549356 VAPA_1c17950 b4a156b8aa7f344f73b0189f19f020ba 146 ProSitePatterns PS01029 Dehydroquinase class II signature. 7 24 - T 12-10-2018 IPR018509 Dehydroquinase, class II, conserved site GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 VAPA_1c17950 b4a156b8aa7f344f73b0189f19f020ba 146 ProDom PD004527 LYASE II 3-DEHYDROQUINATE BIOSYNTHESIS DEHYDRATASE TYPE 3-DEHYDROQUINASE DHQASE AMINO AROMATIC 17 144 5.0E-48 T 12-10-2018 VAPA_1c17950 b4a156b8aa7f344f73b0189f19f020ba 146 Gene3D G3DSA:3.40.50.9100 1 146 3.2E-65 T 12-10-2018 IPR036441 Dehydroquinase, class II superfamily GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 VAPA_1c17950 b4a156b8aa7f344f73b0189f19f020ba 146 TIGRFAM TIGR01088 aroQ: 3-dehydroquinate dehydratase, type II 3 145 8.3E-59 T 12-10-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 VAPA_1c17950 b4a156b8aa7f344f73b0189f19f020ba 146 SUPERFAMILY SSF52304 3 145 5.36E-59 T 12-10-2018 IPR036441 Dehydroquinase, class II superfamily GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 VAPA_1c17950 b4a156b8aa7f344f73b0189f19f020ba 146 Hamap MF_00169 3-dehydroquinate dehydratase [aroQ]. 1 146 69.686 T 12-10-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 VAPA_1c17950 b4a156b8aa7f344f73b0189f19f020ba 146 Pfam PF01220 Dehydroquinase class II 3 144 1.4E-61 T 12-10-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 VAPA_1c17950 b4a156b8aa7f344f73b0189f19f020ba 146 PIRSF PIRSF001399 1 146 1.5E-62 T 12-10-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 VAPA_2c11740 05996604408109e89da7a95f62073807 354 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_2c11740 05996604408109e89da7a95f62073807 354 Pfam PF08402 TOBE domain 276 349 2.8E-9 T 12-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 VAPA_2c11740 05996604408109e89da7a95f62073807 354 SUPERFAMILY SSF52540 4 240 5.32E-82 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_2c11740 05996604408109e89da7a95f62073807 354 Pfam PF00005 ABC transporter 19 160 2.5E-32 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_2c11740 05996604408109e89da7a95f62073807 354 SMART SM00382 27 210 6.0E-16 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_2c11740 05996604408109e89da7a95f62073807 354 SUPERFAMILY SSF50331 266 348 9.07E-5 T 12-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal VAPA_2c11740 05996604408109e89da7a95f62073807 354 Gene3D G3DSA:3.40.50.300 1 236 6.8E-77 T 12-10-2018 VAPA_1c49650 55bf4023c38b303be09f59ab7a5c751f 101 Pfam PF05597 Poly(hydroxyalcanoate) granule associated protein (phasin) 46 89 4.2E-10 T 12-10-2018 IPR008769 Poly granule associated VAPA_2c03270 5abce8f791c350ab68c2630a79a94a60 274 Gene3D G3DSA:3.40.50.12370 6 273 1.2E-27 T 12-10-2018 VAPA_2c03270 5abce8f791c350ab68c2630a79a94a60 274 SUPERFAMILY SSF52402 2 145 1.59E-8 T 12-10-2018 VAPA_2c03270 5abce8f791c350ab68c2630a79a94a60 274 Pfam PF00582 Universal stress protein family 198 272 1.6E-5 T 12-10-2018 IPR006016 UspA VAPA_2c03270 5abce8f791c350ab68c2630a79a94a60 274 SUPERFAMILY SSF52402 155 273 1.42E-16 T 12-10-2018 VAPA_2c03270 5abce8f791c350ab68c2630a79a94a60 274 PRINTS PR01438 Universal stress protein signature 252 274 2.1E-5 T 12-10-2018 IPR006015 Universal stress protein A VAPA_2c03270 5abce8f791c350ab68c2630a79a94a60 274 PRINTS PR01438 Universal stress protein signature 234 246 2.1E-5 T 12-10-2018 IPR006015 Universal stress protein A VAPA_2c03270 5abce8f791c350ab68c2630a79a94a60 274 PRINTS PR01438 Universal stress protein signature 4 22 2.1E-5 T 12-10-2018 IPR006015 Universal stress protein A VAPA_1c48840 c99915458eb417f201a0f7708beb4d6f 436 Pfam PF00069 Protein kinase domain 211 364 4.8E-10 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 VAPA_1c48840 c99915458eb417f201a0f7708beb4d6f 436 SUPERFAMILY SSF56112 202 431 1.75E-24 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily VAPA_1c48840 c99915458eb417f201a0f7708beb4d6f 436 SMART SM00369 37 57 100.0 T 12-10-2018 IPR003591 Leucine-rich repeat, typical subtype VAPA_1c48840 c99915458eb417f201a0f7708beb4d6f 436 SMART SM00369 151 173 130.0 T 12-10-2018 IPR003591 Leucine-rich repeat, typical subtype VAPA_1c48840 c99915458eb417f201a0f7708beb4d6f 436 SMART SM00369 58 81 3.5 T 12-10-2018 IPR003591 Leucine-rich repeat, typical subtype VAPA_1c48840 c99915458eb417f201a0f7708beb4d6f 436 SMART SM00369 128 150 34.0 T 12-10-2018 IPR003591 Leucine-rich repeat, typical subtype VAPA_1c48840 c99915458eb417f201a0f7708beb4d6f 436 SMART SM00369 104 127 0.077 T 12-10-2018 IPR003591 Leucine-rich repeat, typical subtype VAPA_1c48840 c99915458eb417f201a0f7708beb4d6f 436 SUPERFAMILY SSF52058 11 188 5.55E-36 T 12-10-2018 VAPA_1c48840 c99915458eb417f201a0f7708beb4d6f 436 Gene3D G3DSA:3.80.10.10 5 206 3.3E-40 T 12-10-2018 IPR032675 Leucine-rich repeat domain superfamily VAPA_1c48840 c99915458eb417f201a0f7708beb4d6f 436 Gene3D G3DSA:1.10.510.10 207 434 2.1E-18 T 12-10-2018 VAPA_1c48840 c99915458eb417f201a0f7708beb4d6f 436 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 214 237 - T 12-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 VAPA_1c17980 bc485c69c0d26ea29543f8824cf791b8 640 SUPERFAMILY SSF52540 75 344 2.46E-19 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c17980 bc485c69c0d26ea29543f8824cf791b8 640 PIRSF PIRSF000549 1 640 1.6E-288 T 12-10-2018 IPR016230 Serine-protein kinase, PrkA GO:0004672 VAPA_1c17980 bc485c69c0d26ea29543f8824cf791b8 640 Pfam PF08298 PrkA AAA domain 20 376 2.4E-173 T 12-10-2018 IPR013153 PrkA AAA domain VAPA_1c17980 bc485c69c0d26ea29543f8824cf791b8 640 Pfam PF06798 PrkA serine protein kinase C-terminal domain 379 632 4.6E-71 T 12-10-2018 IPR010650 PrkA C-terminal domain VAPA_1c17980 bc485c69c0d26ea29543f8824cf791b8 640 SMART SM00763 19 376 3.9E-211 T 12-10-2018 IPR013153 PrkA AAA domain VAPA_1c42510 a3d562670b309b0b9ddac85f82a5358d 120 PIRSF PIRSF006113 1 119 4.9E-27 T 12-10-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family Reactome: R-HSA-1474151 VAPA_1c42510 a3d562670b309b0b9ddac85f82a5358d 120 Gene3D G3DSA:3.30.479.10 1 118 8.6E-32 T 12-10-2018 IPR038418 6-pyruvoyl tetrahydropterin synthase/QueD superfamily Reactome: R-HSA-1474151 VAPA_1c42510 a3d562670b309b0b9ddac85f82a5358d 120 SUPERFAMILY SSF55620 1 108 6.67E-30 T 12-10-2018 VAPA_1c42510 a3d562670b309b0b9ddac85f82a5358d 120 Pfam PF01242 6-pyruvoyl tetrahydropterin synthase 4 113 8.6E-27 T 12-10-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family Reactome: R-HSA-1474151 VAPA_2c08250 d6e290b0740e39a8eddbd365207afe5c 157 SUPERFAMILY SSF101478 3 97 1.31E-20 T 12-10-2018 IPR036705 ADP-ribosylation/Crystallin J1 superfamily VAPA_2c08250 d6e290b0740e39a8eddbd365207afe5c 157 Pfam PF03747 ADP-ribosylglycohydrolase 9 78 9.2E-18 T 12-10-2018 IPR005502 ADP-ribosylation/Crystallin J1 VAPA_2c08250 d6e290b0740e39a8eddbd365207afe5c 157 Gene3D G3DSA:1.10.4080.10 1 122 4.3E-30 T 12-10-2018 IPR036705 ADP-ribosylation/Crystallin J1 superfamily VAPA_2c08080 3342a9b5cbf8478c88e0248f7683a1b0 159 SUPERFAMILY SSF143744 2 140 3.4E-34 T 12-10-2018 IPR038084 GlcG-like domain superfamily VAPA_2c08080 3342a9b5cbf8478c88e0248f7683a1b0 159 Gene3D G3DSA:3.30.450.150 1 143 1.3E-40 T 12-10-2018 IPR038084 GlcG-like domain superfamily VAPA_2c08080 3342a9b5cbf8478c88e0248f7683a1b0 159 Pfam PF03928 Haem-degrading 7 137 2.8E-26 T 12-10-2018 IPR005624 Haem-degrading VAPA_2c03390 3505d3c3c515ba48afe9bcdf0ee198d4 140 Pfam PF00582 Universal stress protein family 2 140 6.1E-23 T 12-10-2018 IPR006016 UspA VAPA_2c03390 3505d3c3c515ba48afe9bcdf0ee198d4 140 Gene3D G3DSA:3.40.50.620 1 140 4.4E-31 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold VAPA_2c03390 3505d3c3c515ba48afe9bcdf0ee198d4 140 PRINTS PR01438 Universal stress protein signature 118 140 1.8E-9 T 12-10-2018 IPR006015 Universal stress protein A VAPA_2c03390 3505d3c3c515ba48afe9bcdf0ee198d4 140 PRINTS PR01438 Universal stress protein signature 100 112 1.8E-9 T 12-10-2018 IPR006015 Universal stress protein A VAPA_2c03390 3505d3c3c515ba48afe9bcdf0ee198d4 140 SUPERFAMILY SSF52402 2 140 7.03E-31 T 12-10-2018 VAPA_1c25330 be81cb4eeabdb05472f1bf624902e88a 718 Pfam PF00593 TonB dependent receptor 263 717 5.8E-35 T 12-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel VAPA_1c25330 be81cb4eeabdb05472f1bf624902e88a 718 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 64 716 3.9E-85 T 12-10-2018 IPR010105 TonB-dependent siderophore receptor GO:0005506|GO:0015891|GO:0038023 VAPA_1c25330 be81cb4eeabdb05472f1bf624902e88a 718 Gene3D G3DSA:2.40.170.20 172 717 2.4E-72 T 12-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily VAPA_1c25330 be81cb4eeabdb05472f1bf624902e88a 718 Gene3D G3DSA:2.170.130.10 48 171 1.5E-20 T 12-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily VAPA_1c25330 be81cb4eeabdb05472f1bf624902e88a 718 SUPERFAMILY SSF56935 29 717 1.2E-91 T 12-10-2018 VAPA_1c25330 be81cb4eeabdb05472f1bf624902e88a 718 Pfam PF07715 TonB-dependent Receptor Plug Domain 61 159 2.8E-11 T 12-10-2018 IPR012910 TonB-dependent receptor, plug domain VAPA_2c04760 e596401013d66cb81ac230a59d974021 564 SUPERFAMILY SSF53474 199 490 5.98E-42 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_2c04760 e596401013d66cb81ac230a59d974021 564 Pfam PF12551 Poly-beta-hydroxybutyrate polymerase N terminal 15 55 2.3E-16 T 12-10-2018 IPR022211 Poly-beta-hydroxybutyrate polymerase N-terminal VAPA_2c04760 e596401013d66cb81ac230a59d974021 564 Gene3D G3DSA:3.40.50.1820 200 496 3.9E-11 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_2c04760 e596401013d66cb81ac230a59d974021 564 Pfam PF07167 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus 75 241 2.4E-46 T 12-10-2018 IPR010941 Poly-beta-hydroxybutyrate polymerase, N-terminal domain GO:0042619 VAPA_1c34550 5690bf25d1830c040cc8a3bfdc21d0ea 435 Gene3D G3DSA:1.20.1250.20 6 432 1.6E-62 T 12-10-2018 VAPA_1c34550 5690bf25d1830c040cc8a3bfdc21d0ea 435 Pfam PF07690 Major Facilitator Superfamily 25 389 1.8E-43 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 VAPA_1c34550 5690bf25d1830c040cc8a3bfdc21d0ea 435 SUPERFAMILY SSF103473 16 428 9.81E-72 T 12-10-2018 IPR036259 MFS transporter superfamily VAPA_2c00560 7d34c2c0a6f290f884c0c1c23fa8019a 166 Gene3D G3DSA:3.90.79.10 11 151 5.2E-11 T 12-10-2018 VAPA_2c00560 7d34c2c0a6f290f884c0c1c23fa8019a 166 SUPERFAMILY SSF55811 32 148 9.8E-13 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 VAPA_1c01350 def4efcdff75b86aab1427c3447c63fe 331 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 56 326 5.6E-82 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c01350 def4efcdff75b86aab1427c3447c63fe 331 SUPERFAMILY SSF53850 122 297 2.85E-14 T 12-10-2018 VAPA_1c01350 def4efcdff75b86aab1427c3447c63fe 331 PIRSF PIRSF017082 1 330 9.3E-75 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c01350 def4efcdff75b86aab1427c3447c63fe 331 Gene3D G3DSA:3.40.190.150 38 321 6.9E-105 T 12-10-2018 VAPA_1c01350 def4efcdff75b86aab1427c3447c63fe 331 Gene3D G3DSA:3.40.190.10 134 256 6.9E-105 T 12-10-2018 VAPA_1c28540 9eb62e494f685db582743dbd88b6ebac 438 Hamap MF_00671 Tol-Pal system protein TolB [tolB]. 21 432 47.211 T 12-10-2018 IPR014167 Tol-Pal system protein TolB GO:0017038|GO:0042597 VAPA_1c28540 9eb62e494f685db582743dbd88b6ebac 438 TIGRFAM TIGR02800 propeller_TolB: Tol-Pal system beta propeller repeat protein TolB 33 433 6.2E-146 T 12-10-2018 IPR014167 Tol-Pal system protein TolB GO:0017038|GO:0042597 VAPA_1c28540 9eb62e494f685db582743dbd88b6ebac 438 Pfam PF04052 TolB amino-terminal domain 39 138 3.2E-29 T 12-10-2018 IPR007195 TolB, N-terminal GO:0015031|GO:0042597 VAPA_1c28540 9eb62e494f685db582743dbd88b6ebac 438 SUPERFAMILY SSF69304 163 434 3.27E-57 T 12-10-2018 VAPA_1c28540 9eb62e494f685db582743dbd88b6ebac 438 SUPERFAMILY SSF52964 46 170 4.45E-36 T 12-10-2018 VAPA_1c28540 9eb62e494f685db582743dbd88b6ebac 438 Pfam PF07676 WD40-like Beta Propeller Repeat 331 364 1.5E-5 T 12-10-2018 IPR011659 WD40-like Beta Propeller VAPA_1c28540 9eb62e494f685db582743dbd88b6ebac 438 Pfam PF07676 WD40-like Beta Propeller Repeat 202 234 8.2E-5 T 12-10-2018 IPR011659 WD40-like Beta Propeller VAPA_1c28540 9eb62e494f685db582743dbd88b6ebac 438 Pfam PF07676 WD40-like Beta Propeller Repeat 376 398 0.31 T 12-10-2018 IPR011659 WD40-like Beta Propeller VAPA_1c28540 9eb62e494f685db582743dbd88b6ebac 438 Pfam PF07676 WD40-like Beta Propeller Repeat 244 278 6.8E-6 T 12-10-2018 IPR011659 WD40-like Beta Propeller VAPA_1c28540 9eb62e494f685db582743dbd88b6ebac 438 Pfam PF07676 WD40-like Beta Propeller Repeat 287 321 2.3E-11 T 12-10-2018 IPR011659 WD40-like Beta Propeller VAPA_1c28540 9eb62e494f685db582743dbd88b6ebac 438 Gene3D G3DSA:2.120.10.30 174 438 2.3E-85 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like VAPA_1c28540 9eb62e494f685db582743dbd88b6ebac 438 Gene3D G3DSA:3.40.50.10070 34 173 7.1E-37 T 12-10-2018 IPR036752 TolB, N-terminal domain superfamily GO:0015031|GO:0042597 VAPA_1c09090 b54d52c955a81a9b704e6b75c02231fb 119 Pfam PF04993 TfoX N-terminal domain 15 104 1.1E-17 T 12-10-2018 IPR007076 TfoX, N-terminal VAPA_1c09090 b54d52c955a81a9b704e6b75c02231fb 119 Gene3D G3DSA:3.30.1460.30 5 108 2.5E-21 T 12-10-2018 VAPA_1c09090 b54d52c955a81a9b704e6b75c02231fb 119 SUPERFAMILY SSF159894 7 104 6.54E-19 T 12-10-2018 VAPA_1c26300 6492f8500a2b866bf3f14a49a09ca42d 491 SUPERFAMILY SSF53187 40 484 2.74E-48 T 12-10-2018 VAPA_1c26300 6492f8500a2b866bf3f14a49a09ca42d 491 SUPERFAMILY SSF55031 242 379 5.23E-8 T 12-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain VAPA_1c26300 6492f8500a2b866bf3f14a49a09ca42d 491 Gene3D G3DSA:3.40.630.10 40 230 3.1E-40 T 12-10-2018 VAPA_1c26300 6492f8500a2b866bf3f14a49a09ca42d 491 Pfam PF07687 Peptidase dimerisation domain 239 382 4.2E-15 T 12-10-2018 IPR011650 Peptidase M20, dimerisation domain VAPA_1c26300 6492f8500a2b866bf3f14a49a09ca42d 491 Pfam PF01546 Peptidase family M20/M25/M40 116 484 7.6E-32 T 12-10-2018 IPR002933 Peptidase M20 GO:0016787 VAPA_1c47270 80c3f02101dcc8682eca975bf1c6af66 380 Pfam PF13020 Domain of unknown function (DUF3883) 258 355 3.5E-21 T 12-10-2018 IPR024975 Domain of unknown function DUF3883 VAPA_1c37340 b7d7f0e73c5631e71fe101915f41928e 356 PRINTS PR00344 Bacterial sensor protein C-terminal signature 338 351 9.9E-6 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c37340 b7d7f0e73c5631e71fe101915f41928e 356 PRINTS PR00344 Bacterial sensor protein C-terminal signature 311 329 9.9E-6 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c37340 b7d7f0e73c5631e71fe101915f41928e 356 PRINTS PR00344 Bacterial sensor protein C-terminal signature 293 307 9.9E-6 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c37340 b7d7f0e73c5631e71fe101915f41928e 356 SMART SM00387 256 354 1.1E-7 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase VAPA_1c37340 b7d7f0e73c5631e71fe101915f41928e 356 Gene3D G3DSA:3.30.565.10 219 354 4.3E-18 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_1c37340 b7d7f0e73c5631e71fe101915f41928e 356 Pfam PF06580 Histidine kinase 162 241 1.1E-17 T 12-10-2018 IPR010559 Signal transduction histidine kinase, internal region GO:0000155|GO:0000160|GO:0016021 VAPA_1c37340 b7d7f0e73c5631e71fe101915f41928e 356 SUPERFAMILY SSF55874 218 352 3.8E-19 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_1c37340 b7d7f0e73c5631e71fe101915f41928e 356 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 261 353 4.5E-7 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase VAPA_1c20200 b6c0b6135d7ea9b8f7a9f76c9d34435a 412 Pfam PF13609 Gram-negative porin 7 361 6.5E-57 T 12-10-2018 VAPA_1c20200 b6c0b6135d7ea9b8f7a9f76c9d34435a 412 SUPERFAMILY SSF56935 21 412 2.63E-53 T 12-10-2018 VAPA_1c20200 b6c0b6135d7ea9b8f7a9f76c9d34435a 412 PRINTS PR00184 Neisseria sp. porin signature 336 360 3.3E-8 T 12-10-2018 IPR002299 Porin, Neisseria sp. type GO:0015288|GO:0016020|GO:0055085 VAPA_1c20200 b6c0b6135d7ea9b8f7a9f76c9d34435a 412 PRINTS PR00184 Neisseria sp. porin signature 101 120 3.3E-8 T 12-10-2018 IPR002299 Porin, Neisseria sp. type GO:0015288|GO:0016020|GO:0055085 VAPA_1c20200 b6c0b6135d7ea9b8f7a9f76c9d34435a 412 PRINTS PR00184 Neisseria sp. porin signature 64 89 3.3E-8 T 12-10-2018 IPR002299 Porin, Neisseria sp. type GO:0015288|GO:0016020|GO:0055085 VAPA_1c20200 b6c0b6135d7ea9b8f7a9f76c9d34435a 412 Gene3D G3DSA:2.40.160.10 21 412 1.6E-70 T 12-10-2018 IPR023614 Porin domain superfamily VAPA_1c02820 bd0ee83c4d19e36219cbada0d9ba87e3 410 SUPERFAMILY SSF54862 6 116 7.11E-21 T 12-10-2018 VAPA_1c02820 bd0ee83c4d19e36219cbada0d9ba87e3 410 Pfam PF12838 4Fe-4S dicluster domain 24 89 1.4E-12 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain VAPA_1c02820 bd0ee83c4d19e36219cbada0d9ba87e3 410 PIRSF PIRSF000139 6 410 1.1E-111 T 12-10-2018 VAPA_1c02820 bd0ee83c4d19e36219cbada0d9ba87e3 410 Gene3D G3DSA:1.10.1060.10 2 108 5.8E-11 T 12-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 VAPA_1c02820 bd0ee83c4d19e36219cbada0d9ba87e3 410 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 75 86 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site VAPA_1c02820 bd0ee83c4d19e36219cbada0d9ba87e3 410 Pfam PF02754 Cysteine-rich domain 303 387 2.2E-9 T 12-10-2018 IPR004017 Cysteine-rich domain VAPA_1c02820 bd0ee83c4d19e36219cbada0d9ba87e3 410 Pfam PF02754 Cysteine-rich domain 168 254 2.3E-9 T 12-10-2018 IPR004017 Cysteine-rich domain VAPA_1c33120 8091f21f5c82badc44c1e728efb7f8b3 431 Gene3D G3DSA:3.30.499.10 295 392 3.0E-6 T 12-10-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 KEGG: 00290+4.2.1.33 VAPA_1c33120 8091f21f5c82badc44c1e728efb7f8b3 431 Pfam PF04412 Protein of unknown function (DUF521) 1 419 1.0E-122 T 12-10-2018 IPR007506 Aconitase X catalytic domain, putative VAPA_1c33120 8091f21f5c82badc44c1e728efb7f8b3 431 SUPERFAMILY SSF53732 306 378 1.7E-6 T 12-10-2018 IPR036008 Aconitase, iron-sulfur domain KEGG: 00290+4.2.1.33 VAPA_1c44450 7e8d2f4b7c879a463e1d7398b42960f0 194 Gene3D G3DSA:1.10.530.70 16 190 3.6E-16 T 12-10-2018 VAPA_1c44450 7e8d2f4b7c879a463e1d7398b42960f0 194 SUPERFAMILY SSF53955 24 192 1.57E-25 T 12-10-2018 IPR023346 Lysozyme-like domain superfamily VAPA_1c44450 7e8d2f4b7c879a463e1d7398b42960f0 194 Pfam PF00182 Chitinase class I 40 158 6.2E-8 T 12-10-2018 IPR000726 Glycoside hydrolase, family 19, catalytic GO:0004568|GO:0006032|GO:0016998 KEGG: 00520+3.2.1.14|MetaCyc: PWY-6855|MetaCyc: PWY-6902|MetaCyc: PWY-7822 VAPA_1c06610 874d1d659029b6d9472019ff526c62ce 273 SUPERFAMILY SSF54637 158 261 2.12E-10 T 12-10-2018 IPR029069 HotDog domain superfamily VAPA_1c06610 874d1d659029b6d9472019ff526c62ce 273 Gene3D G3DSA:3.10.129.10 45 269 5.1E-18 T 12-10-2018 VAPA_1c01880 cb74af4b11aac1c438af26aabbcb854c 292 SUPERFAMILY SSF161098 96 279 4.58E-27 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c01880 cb74af4b11aac1c438af26aabbcb854c 292 Gene3D G3DSA:1.10.3720.10 93 287 4.8E-19 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c01880 cb74af4b11aac1c438af26aabbcb854c 292 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 117 286 1.4E-23 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 VAPA_1c43110 b5f716b7916b2a5e9e033bef0d3466a6 415 Gene3D G3DSA:1.10.3210.10 203 339 2.3E-20 T 12-10-2018 VAPA_1c43110 b5f716b7916b2a5e9e033bef0d3466a6 415 SUPERFAMILY SSF109604 206 408 3.45E-30 T 12-10-2018 VAPA_1c43110 b5f716b7916b2a5e9e033bef0d3466a6 415 Pfam PF08668 HDOD domain 214 284 2.0E-10 T 12-10-2018 IPR013976 Metal-dependent hydrolase HDOD VAPA_1c23790 e29df3a6121e39d886e03c312787ba64 174 SUPERFAMILY SSF53271 5 169 5.65E-33 T 12-10-2018 IPR029057 Phosphoribosyltransferase-like VAPA_1c23790 e29df3a6121e39d886e03c312787ba64 174 Pfam PF00156 Phosphoribosyl transferase domain 12 158 1.3E-24 T 12-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 VAPA_1c23790 e29df3a6121e39d886e03c312787ba64 174 Gene3D G3DSA:3.40.50.2020 7 171 6.2E-32 T 12-10-2018 VAPA_2c09810 624894dc7e59d7e48d6b5c637b74232f 322 SUPERFAMILY SSF53850 110 282 8.69E-12 T 12-10-2018 VAPA_2c09810 624894dc7e59d7e48d6b5c637b74232f 322 Gene3D G3DSA:3.40.190.10 125 247 7.7E-118 T 12-10-2018 VAPA_2c09810 624894dc7e59d7e48d6b5c637b74232f 322 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 47 318 2.4E-89 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_2c09810 624894dc7e59d7e48d6b5c637b74232f 322 Gene3D G3DSA:3.40.190.150 27 312 7.7E-118 T 12-10-2018 VAPA_2c09810 624894dc7e59d7e48d6b5c637b74232f 322 PIRSF PIRSF017082 1 321 1.8E-86 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c21630 d6bc490f76137e169e536853715116d2 464 Pfam PF07287 Acyclic terpene utilisation family protein AtuA 11 362 7.0E-124 T 12-10-2018 IPR010839 Acyclic terpene utilisation VAPA_1c26660 bf8a783639fc6fb525be560539b43b88 218 Pfam PF00486 Transcriptional regulatory protein, C terminal 145 216 5.5E-17 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 VAPA_1c26660 bf8a783639fc6fb525be560539b43b88 218 SMART SM00862 145 216 5.0E-20 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 VAPA_1c26660 bf8a783639fc6fb525be560539b43b88 218 SUPERFAMILY SSF52172 2 161 1.61E-32 T 12-10-2018 IPR011006 CheY-like superfamily VAPA_1c26660 bf8a783639fc6fb525be560539b43b88 218 Gene3D G3DSA:1.10.10.10 122 218 1.0E-23 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c26660 bf8a783639fc6fb525be560539b43b88 218 Pfam PF00072 Response regulator receiver domain 3 113 5.5E-22 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_1c26660 bf8a783639fc6fb525be560539b43b88 218 SMART SM00448 1 112 7.3E-30 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_1c26660 bf8a783639fc6fb525be560539b43b88 218 Gene3D G3DSA:3.40.50.2300 1 121 4.1E-33 T 12-10-2018 VAPA_1c15600 76a7fec67180ef8ddd6535d4be44dc83 216 TIGRFAM TIGR01498 folK: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase 67 195 1.6E-35 T 12-10-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 VAPA_1c15600 76a7fec67180ef8ddd6535d4be44dc83 216 Pfam PF01288 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) 68 195 2.1E-32 T 12-10-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 VAPA_1c15600 76a7fec67180ef8ddd6535d4be44dc83 216 SUPERFAMILY SSF55083 66 199 9.94E-43 T 12-10-2018 IPR035907 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK superfamily KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 VAPA_1c15600 76a7fec67180ef8ddd6535d4be44dc83 216 Gene3D G3DSA:3.30.70.560 62 214 4.8E-44 T 12-10-2018 IPR035907 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK superfamily KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 VAPA_1c21670 4d7a6583cbd4402b0ba45785609acfda 259 Gene3D G3DSA:3.40.50.360 1 258 1.0E-99 T 12-10-2018 IPR029039 Flavoprotein-like superfamily VAPA_1c21670 4d7a6583cbd4402b0ba45785609acfda 259 SUPERFAMILY SSF52218 2 243 1.64E-69 T 12-10-2018 IPR029039 Flavoprotein-like superfamily VAPA_1c21670 4d7a6583cbd4402b0ba45785609acfda 259 Pfam PF02525 Flavodoxin-like fold 2 209 8.2E-55 T 12-10-2018 IPR003680 Flavodoxin-like fold VAPA_1c02810 a939ff5e73356028ce279d0d81a7c6e8 374 SUPERFAMILY SSF56176 6 175 3.84E-33 T 12-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 VAPA_1c02810 a939ff5e73356028ce279d0d81a7c6e8 374 SUPERFAMILY SSF55103 136 370 3.6E-13 T 12-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 VAPA_1c02810 a939ff5e73356028ce279d0d81a7c6e8 374 Pfam PF01565 FAD binding domain 7 138 1.8E-19 T 12-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 VAPA_1c02810 a939ff5e73356028ce279d0d81a7c6e8 374 Gene3D G3DSA:3.30.465.10 52 175 2.3E-33 T 12-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 VAPA_1c07450 cfbfc037a2c6a572e7ee7b39380cfab7 448 Gene3D G3DSA:3.40.50.150 227 446 3.2E-53 T 12-10-2018 VAPA_1c07450 cfbfc037a2c6a572e7ee7b39380cfab7 448 Pfam PF01189 16S rRNA methyltransferase RsmB/F 258 443 1.3E-52 T 12-10-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 VAPA_1c07450 cfbfc037a2c6a572e7ee7b39380cfab7 448 SUPERFAMILY SSF48013 27 147 8.72E-15 T 12-10-2018 IPR035926 NusB-like superfamily VAPA_1c07450 cfbfc037a2c6a572e7ee7b39380cfab7 448 SUPERFAMILY SSF53335 138 446 3.7E-59 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase VAPA_1c07450 cfbfc037a2c6a572e7ee7b39380cfab7 448 Gene3D G3DSA:3.30.70.1170 171 226 7.8E-14 T 12-10-2018 VAPA_1c07450 cfbfc037a2c6a572e7ee7b39380cfab7 448 TIGRFAM TIGR00563 rsmB: 16S rRNA (cytosine(967)-C(5))-methyltransferase 40 446 1.7E-80 T 12-10-2018 IPR004573 rRNA small subunit methyltransferase B GO:0006364|GO:0008649 VAPA_1c07450 cfbfc037a2c6a572e7ee7b39380cfab7 448 ProSitePatterns PS01153 NOL1/NOP2/sun family signature. 327 338 - T 12-10-2018 IPR018314 Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site GO:0003723|GO:0008168 VAPA_1c07450 cfbfc037a2c6a572e7ee7b39380cfab7 448 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 328 340 1.4E-23 T 12-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase VAPA_1c07450 cfbfc037a2c6a572e7ee7b39380cfab7 448 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 428 445 1.4E-23 T 12-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase VAPA_1c07450 cfbfc037a2c6a572e7ee7b39380cfab7 448 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 218 232 1.4E-23 T 12-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase VAPA_1c07450 cfbfc037a2c6a572e7ee7b39380cfab7 448 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 378 394 1.4E-23 T 12-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase VAPA_1c07450 cfbfc037a2c6a572e7ee7b39380cfab7 448 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 260 270 1.4E-23 T 12-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase VAPA_1c07450 cfbfc037a2c6a572e7ee7b39380cfab7 448 Gene3D G3DSA:1.10.940.10 10 143 5.8E-10 T 12-10-2018 IPR035926 NusB-like superfamily VAPA_1c54300 61eb38969d0e6953ffc324c925172d29 379 SUPERFAMILY SSF53822 31 374 3.83E-81 T 12-10-2018 IPR028082 Periplasmic binding protein-like I VAPA_1c54300 61eb38969d0e6953ffc324c925172d29 379 Pfam PF13458 Periplasmic binding protein 31 369 1.7E-56 T 12-10-2018 IPR028081 Leucine-binding protein domain VAPA_1c54300 61eb38969d0e6953ffc324c925172d29 379 Gene3D G3DSA:3.40.50.2300 32 353 4.4E-90 T 12-10-2018 VAPA_1c54300 61eb38969d0e6953ffc324c925172d29 379 Gene3D G3DSA:3.40.50.2300 151 279 4.4E-90 T 12-10-2018 VAPA_2c06190 2a1a1866cbafdc16e14c53c3ab92f7a3 291 SMART SM00342 190 272 2.5E-20 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 VAPA_2c06190 2a1a1866cbafdc16e14c53c3ab92f7a3 291 Gene3D G3DSA:1.10.10.60 233 282 2.3E-8 T 12-10-2018 VAPA_2c06190 2a1a1866cbafdc16e14c53c3ab92f7a3 291 SUPERFAMILY SSF46689 173 222 7.44E-8 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 VAPA_2c06190 2a1a1866cbafdc16e14c53c3ab92f7a3 291 Gene3D G3DSA:1.10.10.60 172 232 2.4E-11 T 12-10-2018 VAPA_2c06190 2a1a1866cbafdc16e14c53c3ab92f7a3 291 Pfam PF12833 Helix-turn-helix domain 196 273 5.5E-18 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 VAPA_2c06190 2a1a1866cbafdc16e14c53c3ab92f7a3 291 SUPERFAMILY SSF46689 227 273 3.14E-7 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 VAPA_1c13710 8239ada657242d09751315f1db9c1de7 75 Gene3D G3DSA:3.30.110.40 1 75 2.9E-28 T 12-10-2018 IPR036868 TusA-like domain superfamily VAPA_1c13710 8239ada657242d09751315f1db9c1de7 75 ProSitePatterns PS01148 Uncharacterized protein family UPF0033 signature. 7 31 - T 12-10-2018 IPR001455 TusA-like domain VAPA_1c13710 8239ada657242d09751315f1db9c1de7 75 Pfam PF01206 Sulfurtransferase TusA 6 71 5.0E-22 T 12-10-2018 IPR001455 TusA-like domain VAPA_1c13710 8239ada657242d09751315f1db9c1de7 75 SUPERFAMILY SSF64307 2 74 6.67E-23 T 12-10-2018 IPR036868 TusA-like domain superfamily VAPA_1c27660 07416e52786212cab99a45675e042b85 206 SUPERFAMILY SSF55144 34 201 2.27E-26 T 12-10-2018 IPR009097 Cyclic phosphodiesterase VAPA_1c27660 07416e52786212cab99a45675e042b85 206 TIGRFAM TIGR02258 2_5_ligase: 2'-5' RNA ligase 34 193 1.1E-19 T 12-10-2018 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 VAPA_1c27660 07416e52786212cab99a45675e042b85 206 Gene3D G3DSA:3.90.1140.10 33 205 8.8E-33 T 12-10-2018 VAPA_1c27660 07416e52786212cab99a45675e042b85 206 Pfam PF13563 2'-5' RNA ligase superfamily 42 168 5.8E-18 T 12-10-2018 VAPA_2c05410 cc44b4b343244599fbdf284173c74a57 490 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 256 400 1.5E-29 T 12-10-2018 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VAPA_2c05410 cc44b4b343244599fbdf284173c74a57 490 Pfam PF00329 Respiratory-chain NADH dehydrogenase, 30 Kd subunit 69 109 5.9E-6 T 12-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VAPA_2c05410 cc44b4b343244599fbdf284173c74a57 490 SUPERFAMILY SSF143243 16 145 1.7E-18 T 12-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VAPA_2c05410 cc44b4b343244599fbdf284173c74a57 490 Gene3D G3DSA:1.10.645.20 132 489 2.8E-94 T 12-10-2018 IPR038290 NADH-quinone oxidoreductase, subunit D superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VAPA_2c05410 cc44b4b343244599fbdf284173c74a57 490 SUPERFAMILY SSF56762 141 489 5.76E-77 T 12-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VAPA_1c10800 abd6c70fe8d7f3723e9fe0a1d1e15878 332 PIRSF PIRSF017082 1 330 2.5E-80 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c10800 abd6c70fe8d7f3723e9fe0a1d1e15878 332 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 55 326 8.9E-87 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c10800 abd6c70fe8d7f3723e9fe0a1d1e15878 332 Gene3D G3DSA:3.40.190.150 36 322 4.9E-114 T 12-10-2018 VAPA_1c10800 abd6c70fe8d7f3723e9fe0a1d1e15878 332 Gene3D G3DSA:3.40.190.10 133 257 4.9E-114 T 12-10-2018 VAPA_1c10800 abd6c70fe8d7f3723e9fe0a1d1e15878 332 SUPERFAMILY SSF53850 118 292 1.13E-12 T 12-10-2018 VAPA_1c01190 b97e48b0e34c3791bb338b85239838a3 430 TIGRFAM TIGR00786 dctM: TRAP transporter, DctM subunit 20 427 3.9E-99 T 12-10-2018 IPR004681 TRAP transporter large membrane protein DctM GO:0016021 VAPA_1c01190 b97e48b0e34c3791bb338b85239838a3 430 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 11 422 5.7E-88 T 12-10-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit VAPA_1c01190 b97e48b0e34c3791bb338b85239838a3 430 PIRSF PIRSF006066 4 430 9.6E-89 T 12-10-2018 IPR004681 TRAP transporter large membrane protein DctM GO:0016021 VAPA_1c07010 10550528b2d63682d74d7d7b9beefa50 405 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 233 249 8.9E-24 T 12-10-2018 VAPA_1c07010 10550528b2d63682d74d7d7b9beefa50 405 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 258 280 8.9E-24 T 12-10-2018 VAPA_1c07010 10550528b2d63682d74d7d7b9beefa50 405 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 147 165 8.9E-24 T 12-10-2018 VAPA_1c07010 10550528b2d63682d74d7d7b9beefa50 405 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 102 120 8.9E-24 T 12-10-2018 VAPA_1c07010 10550528b2d63682d74d7d7b9beefa50 405 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 8.9E-24 T 12-10-2018 VAPA_1c07010 10550528b2d63682d74d7d7b9beefa50 405 Gene3D G3DSA:3.30.390.30 318 405 2.2E-28 T 12-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 VAPA_1c07010 10550528b2d63682d74d7d7b9beefa50 405 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 273 280 1.8E-13 T 12-10-2018 VAPA_1c07010 10550528b2d63682d74d7d7b9beefa50 405 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 5 27 1.8E-13 T 12-10-2018 VAPA_1c07010 10550528b2d63682d74d7d7b9beefa50 405 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 147 172 1.8E-13 T 12-10-2018 VAPA_1c07010 10550528b2d63682d74d7d7b9beefa50 405 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 234 248 1.8E-13 T 12-10-2018 VAPA_1c07010 10550528b2d63682d74d7d7b9beefa50 405 SUPERFAMILY SSF55424 316 405 1.01E-28 T 12-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 VAPA_1c07010 10550528b2d63682d74d7d7b9beefa50 405 SUPERFAMILY SSF51905 3 193 3.56E-48 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c07010 10550528b2d63682d74d7d7b9beefa50 405 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 303 1.3E-66 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 VAPA_1c07010 10550528b2d63682d74d7d7b9beefa50 405 SUPERFAMILY SSF51905 146 312 2.94E-31 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c07010 10550528b2d63682d74d7d7b9beefa50 405 Gene3D G3DSA:3.50.50.60 115 240 9.5E-106 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c07010 10550528b2d63682d74d7d7b9beefa50 405 Pfam PF14759 Reductase C-terminal 322 405 5.3E-29 T 12-10-2018 IPR028202 Reductase, C-terminal VAPA_1c07010 10550528b2d63682d74d7d7b9beefa50 405 Gene3D G3DSA:3.50.50.60 6 309 9.5E-106 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c40520 43cee8ecb9955c4e9b1d4e2298727858 323 SUPERFAMILY SSF88713 10 314 1.2E-87 T 12-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 VAPA_1c40520 43cee8ecb9955c4e9b1d4e2298727858 323 TIGRFAM TIGR03212 uraD_N-term-dom: putative urate catabolism protein 10 313 6.1E-149 T 12-10-2018 IPR017625 PuuE allantoinase/chitin deacetylase 1 VAPA_1c40520 43cee8ecb9955c4e9b1d4e2298727858 323 Gene3D G3DSA:3.20.20.370 3 321 4.4E-108 T 12-10-2018 VAPA_1c40520 43cee8ecb9955c4e9b1d4e2298727858 323 Pfam PF01522 Polysaccharide deacetylase 80 167 7.6E-13 T 12-10-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 VAPA_1c52830 d1dc9aa7e4b0782cedd6a22fde1d74ac 397 Gene3D G3DSA:3.30.470.20 188 388 9.1E-75 T 12-10-2018 VAPA_1c52830 d1dc9aa7e4b0782cedd6a22fde1d74ac 397 TIGRFAM TIGR01161 purK: phosphoribosylaminoimidazole carboxylase, ATPase subunit 14 375 5.7E-112 T 12-10-2018 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 VAPA_1c52830 d1dc9aa7e4b0782cedd6a22fde1d74ac 397 Hamap MF_01928 N5-carboxyaminoimidazole ribonucleotide synthase [purK]. 14 372 38.712 T 12-10-2018 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 VAPA_1c52830 d1dc9aa7e4b0782cedd6a22fde1d74ac 397 SUPERFAMILY SSF56059 110 306 1.26E-55 T 12-10-2018 VAPA_1c52830 d1dc9aa7e4b0782cedd6a22fde1d74ac 397 SUPERFAMILY SSF51246 311 386 1.02E-16 T 12-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 VAPA_1c52830 d1dc9aa7e4b0782cedd6a22fde1d74ac 397 Gene3D G3DSA:3.40.50.20 7 119 2.9E-37 T 12-10-2018 VAPA_1c52830 d1dc9aa7e4b0782cedd6a22fde1d74ac 397 Gene3D G3DSA:3.30.1490.20 121 186 1.4E-20 T 12-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 VAPA_1c52830 d1dc9aa7e4b0782cedd6a22fde1d74ac 397 SUPERFAMILY SSF52440 7 107 1.58E-25 T 12-10-2018 IPR016185 Pre-ATP-grasp domain superfamily VAPA_1c52830 d1dc9aa7e4b0782cedd6a22fde1d74ac 397 Pfam PF02222 ATP-grasp domain 120 288 3.2E-47 T 12-10-2018 IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type VAPA_1c27710 c9763ce36a091b978667548cce349dd2 301 Gene3D G3DSA:3.40.50.1980 34 177 2.6E-38 T 12-10-2018 VAPA_1c27710 c9763ce36a091b978667548cce349dd2 301 PRINTS PR00691 Adhesin B signature 184 201 5.8E-19 T 12-10-2018 IPR006129 Adhesin B GO:0007155 VAPA_1c27710 c9763ce36a091b978667548cce349dd2 301 PRINTS PR00691 Adhesin B signature 33 54 5.8E-19 T 12-10-2018 IPR006129 Adhesin B GO:0007155 VAPA_1c27710 c9763ce36a091b978667548cce349dd2 301 PRINTS PR00691 Adhesin B signature 233 250 5.8E-19 T 12-10-2018 IPR006129 Adhesin B GO:0007155 VAPA_1c27710 c9763ce36a091b978667548cce349dd2 301 PRINTS PR00691 Adhesin B signature 58 76 5.8E-19 T 12-10-2018 IPR006129 Adhesin B GO:0007155 VAPA_1c27710 c9763ce36a091b978667548cce349dd2 301 PRINTS PR00691 Adhesin B signature 255 273 5.8E-19 T 12-10-2018 IPR006129 Adhesin B GO:0007155 VAPA_1c27710 c9763ce36a091b978667548cce349dd2 301 PRINTS PR00691 Adhesin B signature 276 294 5.8E-19 T 12-10-2018 IPR006129 Adhesin B GO:0007155 VAPA_1c27710 c9763ce36a091b978667548cce349dd2 301 PRINTS PR00690 Adhesin family signature 184 205 8.9E-29 T 12-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 VAPA_1c27710 c9763ce36a091b978667548cce349dd2 301 PRINTS PR00690 Adhesin family signature 64 77 8.9E-29 T 12-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 VAPA_1c27710 c9763ce36a091b978667548cce349dd2 301 PRINTS PR00690 Adhesin family signature 77 94 8.9E-29 T 12-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 VAPA_1c27710 c9763ce36a091b978667548cce349dd2 301 PRINTS PR00690 Adhesin family signature 263 282 8.9E-29 T 12-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 VAPA_1c27710 c9763ce36a091b978667548cce349dd2 301 PRINTS PR00690 Adhesin family signature 33 51 8.9E-29 T 12-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 VAPA_1c27710 c9763ce36a091b978667548cce349dd2 301 PRINTS PR00690 Adhesin family signature 237 255 8.9E-29 T 12-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 VAPA_1c27710 c9763ce36a091b978667548cce349dd2 301 Pfam PF01297 Zinc-uptake complex component A periplasmic 36 296 2.6E-73 T 12-10-2018 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 VAPA_1c27710 c9763ce36a091b978667548cce349dd2 301 SUPERFAMILY SSF53807 32 298 5.89E-79 T 12-10-2018 VAPA_1c27710 c9763ce36a091b978667548cce349dd2 301 Gene3D G3DSA:3.40.50.1980 178 300 1.3E-45 T 12-10-2018 VAPA_1c06200 c8268a3dd1b3ff640417e116a9611b8e 558 Pfam PF00498 FHA domain 28 94 3.1E-11 T 12-10-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 VAPA_1c06200 c8268a3dd1b3ff640417e116a9611b8e 558 SMART SM00240 26 77 3.3E-4 T 12-10-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 VAPA_1c06200 c8268a3dd1b3ff640417e116a9611b8e 558 SUPERFAMILY SSF49879 15 110 2.28E-16 T 12-10-2018 IPR008984 SMAD/FHA domain superfamily GO:0005515 VAPA_1c06200 c8268a3dd1b3ff640417e116a9611b8e 558 Gene3D G3DSA:2.60.200.20 2 105 2.1E-14 T 12-10-2018 VAPA_1c06200 c8268a3dd1b3ff640417e116a9611b8e 558 TIGRFAM TIGR03354 VI_FHA: type VI secretion system FHA domain protein 267 550 1.7E-57 T 12-10-2018 IPR017735 Type VI secretion system, FHA domain-containing protein VAPA_2c08410 d40dd46e58483830d47909669585a9b3 412 Gene3D G3DSA:3.50.50.60 4 323 4.5E-127 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_2c08410 d40dd46e58483830d47909669585a9b3 412 SUPERFAMILY SSF51905 2 358 1.81E-17 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_2c08410 d40dd46e58483830d47909669585a9b3 412 Gene3D G3DSA:3.30.9.40 65 272 4.5E-127 T 12-10-2018 VAPA_1c49730 35edb541f0beb8f8ef3869e286595b8a 217 SUPERFAMILY SSF52540 27 214 3.47E-30 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c49730 35edb541f0beb8f8ef3869e286595b8a 217 Gene3D G3DSA:3.40.50.300 50 217 1.2E-51 T 12-10-2018 VAPA_1c53870 6c26fbe160fd0912325eb477b2690d3f 369 SUPERFAMILY SSF53383 20 366 2.02E-106 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase VAPA_1c53870 6c26fbe160fd0912325eb477b2690d3f 369 Gene3D G3DSA:3.90.1150.10 241 368 1.3E-30 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 VAPA_1c53870 6c26fbe160fd0912325eb477b2690d3f 369 PIRSF PIRSF000390 1 369 3.6E-101 T 12-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase VAPA_1c53870 6c26fbe160fd0912325eb477b2690d3f 369 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 20 363 4.4E-119 T 12-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase VAPA_1c53870 6c26fbe160fd0912325eb477b2690d3f 369 Gene3D G3DSA:3.40.640.10 1 240 7.4E-92 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 VAPA_1c02990 95b1a051b9e42652556cb89d4c18857c 211 SUPERFAMILY SSF56529 9 206 5.36E-36 T 12-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 VAPA_1c02990 95b1a051b9e42652556cb89d4c18857c 211 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 12 205 3.3E-28 T 12-10-2018 IPR011234 Fumarylacetoacetase-like, C-terminal GO:0003824 VAPA_1c02990 95b1a051b9e42652556cb89d4c18857c 211 Gene3D G3DSA:3.90.850.10 9 211 6.8E-37 T 12-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 VAPA_2c09930 6000bdc79a611f2eca521980cf99d099 181 Gene3D G3DSA:1.20.120.450 1 153 2.5E-20 T 12-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes VAPA_2c09930 6000bdc79a611f2eca521980cf99d099 181 Pfam PF05163 DinB family 1 159 4.1E-13 T 12-10-2018 IPR007837 DNA damage-inducible protein DinB VAPA_2c09930 6000bdc79a611f2eca521980cf99d099 181 SUPERFAMILY SSF109854 4 137 1.1E-21 T 12-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes VAPA_1c27740 ca64c1aab439bf63d2d2bfad1276a1fd 125 SUPERFAMILY SSF46785 22 119 2.52E-24 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c27740 ca64c1aab439bf63d2d2bfad1276a1fd 125 Gene3D G3DSA:1.10.10.10 15 125 4.1E-28 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c27740 ca64c1aab439bf63d2d2bfad1276a1fd 125 Pfam PF01638 HxlR-like helix-turn-helix 34 118 1.1E-20 T 12-10-2018 IPR002577 Helix-turn-helix, HxlR type VAPA_1c21510 13c04190d496b65f33e63b0e3430a312 82 Gene3D G3DSA:2.20.110.10 7 77 5.1E-7 T 12-10-2018 VAPA_1c21510 13c04190d496b65f33e63b0e3430a312 82 SUPERFAMILY SSF82185 10 69 7.85E-7 T 12-10-2018 VAPA_2c06230 1d7a685a9868a9bcfedcf314fbb3e796 690 PIRSF PIRSF005419 12 690 2.6E-218 T 12-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 VAPA_2c06230 1d7a685a9868a9bcfedcf314fbb3e796 690 ProSitePatterns PS00994 Bacterial export FHIPEP family signature. 148 171 - T 12-10-2018 IPR025505 FHIPEP conserved site VAPA_2c06230 1d7a685a9868a9bcfedcf314fbb3e796 690 TIGRFAM TIGR01399 hrcV: type III secretion protein, HrcV family 25 683 1.6E-226 T 12-10-2018 IPR006302 Type III secretion protein HrcV GO:0015031|GO:0016021 VAPA_2c06230 1d7a685a9868a9bcfedcf314fbb3e796 690 Pfam PF00771 FHIPEP family 37 676 8.1E-209 T 12-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 VAPA_2c06230 1d7a685a9868a9bcfedcf314fbb3e796 690 Gene3D G3DSA:1.10.8.540 499 585 4.2E-27 T 12-10-2018 VAPA_2c06230 1d7a685a9868a9bcfedcf314fbb3e796 690 Gene3D G3DSA:1.10.490.80 589 684 6.3E-17 T 12-10-2018 VAPA_2c06230 1d7a685a9868a9bcfedcf314fbb3e796 690 Gene3D G3DSA:3.40.30.60 366 498 1.2E-15 T 12-10-2018 VAPA_2c06230 1d7a685a9868a9bcfedcf314fbb3e796 690 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 44 57 2.2E-53 T 12-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 VAPA_2c06230 1d7a685a9868a9bcfedcf314fbb3e796 690 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 81 100 2.2E-53 T 12-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 VAPA_2c06230 1d7a685a9868a9bcfedcf314fbb3e796 690 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 143 159 2.2E-53 T 12-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 VAPA_2c06230 1d7a685a9868a9bcfedcf314fbb3e796 690 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 192 209 2.2E-53 T 12-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 VAPA_2c06230 1d7a685a9868a9bcfedcf314fbb3e796 690 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 162 180 2.2E-53 T 12-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 VAPA_2c06230 1d7a685a9868a9bcfedcf314fbb3e796 690 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 243 257 2.2E-53 T 12-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 VAPA_1c29500 13837daa3121844eb801a7c9f95d376d 189 Hamap MF_00040 Ribosome-recycling factor [frr]. 7 189 26.206 T 12-10-2018 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 VAPA_1c29500 13837daa3121844eb801a7c9f95d376d 189 Gene3D G3DSA:3.30.1360.40 35 109 2.7E-63 T 12-10-2018 VAPA_1c29500 13837daa3121844eb801a7c9f95d376d 189 Pfam PF01765 Ribosome recycling factor 24 187 6.6E-60 T 12-10-2018 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 VAPA_1c29500 13837daa3121844eb801a7c9f95d376d 189 SUPERFAMILY SSF55194 9 187 6.8E-66 T 12-10-2018 IPR036191 RRF superfamily Reactome: R-HSA-5419276 VAPA_1c29500 13837daa3121844eb801a7c9f95d376d 189 Gene3D G3DSA:1.10.132.20 16 186 2.7E-63 T 12-10-2018 VAPA_1c29500 13837daa3121844eb801a7c9f95d376d 189 TIGRFAM TIGR00496 frr: ribosome recycling factor 15 189 1.2E-66 T 12-10-2018 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 VAPA_1c20790 dd933c2fd5626b4dd80a7c849ed4d06b 179 Pfam PF13669 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 9 131 9.3E-34 T 12-10-2018 VAPA_1c20790 dd933c2fd5626b4dd80a7c849ed4d06b 179 Gene3D G3DSA:3.10.180.10 4 145 5.1E-35 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase VAPA_1c20790 dd933c2fd5626b4dd80a7c849ed4d06b 179 SUPERFAMILY SSF54593 8 146 2.4E-19 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase VAPA_2c05510 7d03c0557beb9a1b88f193c49c759c53 318 SUPERFAMILY SSF53850 104 274 4.34E-9 T 12-10-2018 VAPA_2c05510 7d03c0557beb9a1b88f193c49c759c53 318 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 43 312 6.1E-75 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_2c05510 7d03c0557beb9a1b88f193c49c759c53 318 Gene3D G3DSA:3.40.190.150 25 304 9.5E-101 T 12-10-2018 VAPA_2c05510 7d03c0557beb9a1b88f193c49c759c53 318 Gene3D G3DSA:3.40.190.10 119 241 9.5E-101 T 12-10-2018 VAPA_2c05510 7d03c0557beb9a1b88f193c49c759c53 318 PIRSF PIRSF017082 3 316 3.1E-80 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c27950 068e20d84964c4ab876c51c4944718d9 144 Gene3D G3DSA:3.40.50.1010 3 136 2.8E-24 T 12-10-2018 VAPA_1c27950 068e20d84964c4ab876c51c4944718d9 144 SUPERFAMILY SSF88723 4 138 4.21E-15 T 12-10-2018 IPR029060 PIN-like domain superfamily VAPA_1c17710 132b91e4bd04370a9792e0bdbca52210 363 Gene3D G3DSA:3.20.20.140 4 358 1.1E-96 T 12-10-2018 VAPA_1c17710 132b91e4bd04370a9792e0bdbca52210 363 SUPERFAMILY SSF51556 14 352 7.78E-62 T 12-10-2018 IPR032466 Metal-dependent hydrolase VAPA_1c17710 132b91e4bd04370a9792e0bdbca52210 363 Pfam PF00962 Adenosine/AMP deaminase 18 339 4.9E-40 T 12-10-2018 IPR001365 Adenosine/AMP deaminase domain GO:0019239 Reactome: R-HSA-74217 VAPA_1c17710 132b91e4bd04370a9792e0bdbca52210 363 TIGRFAM TIGR01430 aden_deam: adenosine deaminase 19 337 8.6E-65 T 12-10-2018 IPR006330 Adenosine/adenine deaminase GO:0019239 Reactome: R-HSA-74217 VAPA_1c08510 6812ed2a59b4eb5f6198b2fa10404b1d 282 Gene3D G3DSA:3.90.850.10 67 281 7.8E-84 T 12-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 VAPA_1c08510 6812ed2a59b4eb5f6198b2fa10404b1d 282 SUPERFAMILY SSF56529 62 279 9.81E-81 T 12-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 VAPA_1c08510 6812ed2a59b4eb5f6198b2fa10404b1d 282 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 73 277 2.5E-67 T 12-10-2018 IPR011234 Fumarylacetoacetase-like, C-terminal GO:0003824 VAPA_1c32010 cdefee9d604de40fa3f769e9687a37db 385 Pfam PF13458 Periplasmic binding protein 40 364 1.7E-50 T 12-10-2018 IPR028081 Leucine-binding protein domain VAPA_1c32010 cdefee9d604de40fa3f769e9687a37db 385 Gene3D G3DSA:3.40.50.2300 40 373 9.8E-80 T 12-10-2018 VAPA_1c32010 cdefee9d604de40fa3f769e9687a37db 385 SUPERFAMILY SSF53822 39 383 4.12E-58 T 12-10-2018 IPR028082 Periplasmic binding protein-like I VAPA_1c32010 cdefee9d604de40fa3f769e9687a37db 385 Gene3D G3DSA:3.40.50.2300 158 375 9.8E-80 T 12-10-2018 VAPA_1c44330 4898c2152e15b6f5881eb13b78058d7c 324 Gene3D G3DSA:3.40.190.10 125 248 2.2E-91 T 12-10-2018 VAPA_1c44330 4898c2152e15b6f5881eb13b78058d7c 324 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 46 318 1.1E-65 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c44330 4898c2152e15b6f5881eb13b78058d7c 324 SUPERFAMILY SSF53850 106 289 5.89E-9 T 12-10-2018 VAPA_1c44330 4898c2152e15b6f5881eb13b78058d7c 324 PIRSF PIRSF017082 2 323 5.2E-62 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c44330 4898c2152e15b6f5881eb13b78058d7c 324 Gene3D G3DSA:3.40.190.150 26 313 2.2E-91 T 12-10-2018 VAPA_2c01130 0314ac9ed1f2f2e97eb42845b474b28b 275 Gene3D G3DSA:3.40.50.720 1 273 8.1E-72 T 12-10-2018 VAPA_2c01130 0314ac9ed1f2f2e97eb42845b474b28b 275 SUPERFAMILY SSF51735 13 256 1.63E-72 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_2c01130 0314ac9ed1f2f2e97eb42845b474b28b 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 218 238 3.9E-21 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c01130 0314ac9ed1f2f2e97eb42845b474b28b 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 182 199 3.9E-21 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c01130 0314ac9ed1f2f2e97eb42845b474b28b 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 15 32 3.9E-21 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c01130 0314ac9ed1f2f2e97eb42845b474b28b 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 89 100 3.9E-21 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c01130 0314ac9ed1f2f2e97eb42845b474b28b 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 161 180 3.9E-21 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c01130 0314ac9ed1f2f2e97eb42845b474b28b 275 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 22 254 1.8E-55 T 12-10-2018 VAPA_1c54280 96a3a8d6785e9c161cedd71b24d679ec 367 SUPERFAMILY SSF54373 205 306 1.57E-12 T 12-10-2018 VAPA_1c54280 96a3a8d6785e9c161cedd71b24d679ec 367 Pfam PF01266 FAD dependent oxidoreductase 5 345 2.0E-62 T 12-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 VAPA_1c54280 96a3a8d6785e9c161cedd71b24d679ec 367 SUPERFAMILY SSF51905 3 361 1.14E-43 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c54280 96a3a8d6785e9c161cedd71b24d679ec 367 Gene3D G3DSA:3.30.9.10 81 305 9.0E-75 T 12-10-2018 VAPA_1c54280 96a3a8d6785e9c161cedd71b24d679ec 367 Gene3D G3DSA:3.50.50.60 5 346 9.0E-75 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c36030 63c2330b14d343084ee99383214ac133 204 Gene3D G3DSA:3.90.79.10 11 191 1.3E-51 T 12-10-2018 VAPA_1c36030 63c2330b14d343084ee99383214ac133 204 SUPERFAMILY SSF55811 16 184 6.09E-48 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 VAPA_1c36030 63c2330b14d343084ee99383214ac133 204 Pfam PF00293 NUDIX domain 53 161 2.0E-14 T 12-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 VAPA_2c12380 fc776976b429a68d6647e8feb802632f 367 ProSitePatterns PS00921 Nitrilases / cyanide hydratase active site signature. 161 174 - T 12-10-2018 IPR000132 Nitrilase/cyanide hydratase, conserved site GO:0016810 VAPA_2c12380 fc776976b429a68d6647e8feb802632f 367 Pfam PF00795 Carbon-nitrogen hydrolase 10 286 3.0E-54 T 12-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 VAPA_2c12380 fc776976b429a68d6647e8feb802632f 367 SUPERFAMILY SSF56317 8 309 3.14E-74 T 12-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily VAPA_2c12380 fc776976b429a68d6647e8feb802632f 367 Gene3D G3DSA:3.60.110.10 2 294 5.6E-102 T 12-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily VAPA_2c08240 24f1bd79e203aacf0cacacdae88e009d 82 Pfam PF00665 Integrase core domain 8 74 1.6E-12 T 12-10-2018 IPR001584 Integrase, catalytic core GO:0015074 VAPA_2c08240 24f1bd79e203aacf0cacacdae88e009d 82 Gene3D G3DSA:3.30.420.10 2 81 7.6E-10 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 VAPA_2c08240 24f1bd79e203aacf0cacacdae88e009d 82 SUPERFAMILY SSF53098 5 78 5.77E-15 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily VAPA_1c26440 7bf9e2f1d9268adb501b7ed0787ae3d1 396 Pfam PF07690 Major Facilitator Superfamily 10 314 4.0E-37 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 VAPA_1c26440 7bf9e2f1d9268adb501b7ed0787ae3d1 396 Gene3D G3DSA:1.20.1250.20 3 378 1.3E-48 T 12-10-2018 VAPA_1c26440 7bf9e2f1d9268adb501b7ed0787ae3d1 396 SUPERFAMILY SSF103473 3 377 2.62E-60 T 12-10-2018 IPR036259 MFS transporter superfamily VAPA_1c32260 97d7c5987e8e6da491f9a8780ae6eab6 115 Pfam PF09723 Zinc ribbon domain 1 39 8.4E-12 T 12-10-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain VAPA_1c32260 97d7c5987e8e6da491f9a8780ae6eab6 115 TIGRFAM TIGR02605 CxxC_CxxC_SSSS: putative regulatory protein, FmdB family 1 43 3.6E-14 T 12-10-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain VAPA_1c32260 97d7c5987e8e6da491f9a8780ae6eab6 115 SMART SM00834 1 41 1.8E-14 T 12-10-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain VAPA_1c50560 07a4d804a65a23779332d44d1e9e23e0 176 TIGRFAM TIGR01145 ATP_synt_delta: ATP synthase F1, delta subunit 7 172 1.4E-34 T 12-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 VAPA_1c50560 07a4d804a65a23779332d44d1e9e23e0 176 Pfam PF00213 ATP synthase delta (OSCP) subunit 7 174 4.7E-45 T 12-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 VAPA_1c50560 07a4d804a65a23779332d44d1e9e23e0 176 Hamap MF_01416 ATP synthase subunit delta [atpD]. 3 176 18.043 T 12-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 VAPA_1c50560 07a4d804a65a23779332d44d1e9e23e0 176 SUPERFAMILY SSF47928 3 104 1.83E-20 T 12-10-2018 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 VAPA_1c50560 07a4d804a65a23779332d44d1e9e23e0 176 Gene3D G3DSA:1.10.520.20 2 104 3.6E-22 T 12-10-2018 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 VAPA_1c50560 07a4d804a65a23779332d44d1e9e23e0 176 PRINTS PR00125 ATP synthase delta subunit signature 7 26 2.2E-22 T 12-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 VAPA_1c50560 07a4d804a65a23779332d44d1e9e23e0 176 PRINTS PR00125 ATP synthase delta subunit signature 84 98 2.2E-22 T 12-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 VAPA_1c50560 07a4d804a65a23779332d44d1e9e23e0 176 PRINTS PR00125 ATP synthase delta subunit signature 134 149 2.2E-22 T 12-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 VAPA_1c50560 07a4d804a65a23779332d44d1e9e23e0 176 PRINTS PR00125 ATP synthase delta subunit signature 149 167 2.2E-22 T 12-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 VAPA_1c50560 07a4d804a65a23779332d44d1e9e23e0 176 PRINTS PR00125 ATP synthase delta subunit signature 73 84 2.2E-22 T 12-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 VAPA_1c10980 9b6df438a776ad05a89156945c929a86 356 SUPERFAMILY SSF53822 31 343 4.71E-67 T 12-10-2018 IPR028082 Periplasmic binding protein-like I VAPA_1c10980 9b6df438a776ad05a89156945c929a86 356 Pfam PF13407 Periplasmic binding protein domain 32 308 1.8E-60 T 12-10-2018 IPR025997 Periplasmic binding protein VAPA_1c10980 9b6df438a776ad05a89156945c929a86 356 Gene3D G3DSA:3.40.50.2300 32 330 1.3E-130 T 12-10-2018 VAPA_1c10980 9b6df438a776ad05a89156945c929a86 356 Gene3D G3DSA:3.40.50.2300 134 350 1.3E-130 T 12-10-2018 VAPA_1c16760 cf8ad11acd436542f166dd4f88881b37 401 Pfam PF13458 Periplasmic binding protein 33 369 2.9E-68 T 12-10-2018 IPR028081 Leucine-binding protein domain VAPA_1c16760 cf8ad11acd436542f166dd4f88881b37 401 Gene3D G3DSA:3.40.50.2300 149 370 3.8E-101 T 12-10-2018 VAPA_1c16760 cf8ad11acd436542f166dd4f88881b37 401 Gene3D G3DSA:3.40.50.2300 55 362 3.8E-101 T 12-10-2018 VAPA_1c16760 cf8ad11acd436542f166dd4f88881b37 401 SUPERFAMILY SSF53822 33 399 3.7E-75 T 12-10-2018 IPR028082 Periplasmic binding protein-like I VAPA_1c09160 dff1bf9a710974c055eb2f35406294e0 585 Gene3D G3DSA:3.10.105.10 335 560 4.5E-91 T 12-10-2018 VAPA_1c09160 dff1bf9a710974c055eb2f35406294e0 585 Gene3D G3DSA:3.40.190.10 253 570 4.5E-91 T 12-10-2018 VAPA_1c09160 dff1bf9a710974c055eb2f35406294e0 585 PIRSF PIRSF002741 40 578 2.3E-67 T 12-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 VAPA_1c09160 dff1bf9a710974c055eb2f35406294e0 585 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 116 477 5.5E-64 T 12-10-2018 IPR000914 Solute-binding protein family 5 domain VAPA_1c09160 dff1bf9a710974c055eb2f35406294e0 585 Gene3D G3DSA:3.90.76.10 96 252 4.5E-91 T 12-10-2018 VAPA_1c09160 dff1bf9a710974c055eb2f35406294e0 585 SUPERFAMILY SSF53850 63 584 2.17E-96 T 12-10-2018 VAPA_2c12170 fc9ad3b926d381b6bfb5eb65f3926657 254 Gene3D G3DSA:3.40.50.300 62 247 1.2E-38 T 12-10-2018 VAPA_2c12170 fc9ad3b926d381b6bfb5eb65f3926657 254 SMART SM00382 98 231 2.2E-9 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_2c12170 fc9ad3b926d381b6bfb5eb65f3926657 254 Pfam PF01695 IstB-like ATP binding protein 54 230 4.9E-39 T 12-10-2018 IPR002611 IstB-like ATP-binding protein GO:0005524 VAPA_2c12170 fc9ad3b926d381b6bfb5eb65f3926657 254 PIRSF PIRSF003073 1 252 1.3E-72 T 12-10-2018 IPR028350 DNA replication protein DnaC/insertion sequence putative ATP-binding protein VAPA_2c12170 fc9ad3b926d381b6bfb5eb65f3926657 254 SUPERFAMILY SSF52540 68 228 9.55E-21 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_2c09430 36d60b092f812feb0e5c8dcfa8f11263 362 Gene3D G3DSA:3.20.20.70 3 333 4.4E-73 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 VAPA_2c09430 36d60b092f812feb0e5c8dcfa8f11263 362 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 5 321 8.4E-48 T 12-10-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 VAPA_2c09430 36d60b092f812feb0e5c8dcfa8f11263 362 SUPERFAMILY SSF51395 3 334 6.48E-72 T 12-10-2018 VAPA_1c13180 7071c8b6373c8d2aa00a119919f4ad4f 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 26 37 4.6E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c13180 7071c8b6373c8d2aa00a119919f4ad4f 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 47 58 4.6E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c13180 7071c8b6373c8d2aa00a119919f4ad4f 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 37 47 4.6E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c13180 7071c8b6373c8d2aa00a119919f4ad4f 308 Gene3D G3DSA:3.40.190.290 97 306 3.7E-38 T 12-10-2018 VAPA_1c13180 7071c8b6373c8d2aa00a119919f4ad4f 308 SUPERFAMILY SSF46785 9 118 1.92E-22 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c13180 7071c8b6373c8d2aa00a119919f4ad4f 308 SUPERFAMILY SSF53850 97 303 1.86E-36 T 12-10-2018 VAPA_1c13180 7071c8b6373c8d2aa00a119919f4ad4f 308 Pfam PF03466 LysR substrate binding domain 94 300 7.1E-37 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_1c13180 7071c8b6373c8d2aa00a119919f4ad4f 308 Gene3D G3DSA:1.10.10.10 5 88 1.7E-23 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c13180 7071c8b6373c8d2aa00a119919f4ad4f 308 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 11 69 5.4E-22 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c53020 94cfd7db84eb4e96dd42506552c67eda 286 SUPERFAMILY SSF50486 182 285 2.35E-30 T 12-10-2018 IPR011034 Formyl transferase-like, C-terminal domain superfamily GO:0003824 VAPA_1c53020 94cfd7db84eb4e96dd42506552c67eda 286 ProSitePatterns PS00373 Phosphoribosylglycinamide formyltransferase active site. 112 135 - T 12-10-2018 IPR001555 Phosphoribosylglycinamide formyltransferase, active site KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 VAPA_1c53020 94cfd7db84eb4e96dd42506552c67eda 286 Pfam PF00551 Formyl transferase 1 159 1.4E-38 T 12-10-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 VAPA_1c53020 94cfd7db84eb4e96dd42506552c67eda 286 TIGRFAM TIGR00460 fmt: methionyl-tRNA formyltransferase 1 278 9.1E-75 T 12-10-2018 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 VAPA_1c53020 94cfd7db84eb4e96dd42506552c67eda 286 Hamap MF_00182 Methionyl-tRNA formyltransferase [fmt]. 1 280 29.904 T 12-10-2018 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 VAPA_1c53020 94cfd7db84eb4e96dd42506552c67eda 286 Gene3D G3DSA:3.10.25.10 183 286 1.1E-28 T 12-10-2018 IPR037022 Formyl transferase, C-terminal domain superfamily GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 VAPA_1c53020 94cfd7db84eb4e96dd42506552c67eda 286 Pfam PF02911 Formyl transferase, C-terminal domain 180 277 9.3E-26 T 12-10-2018 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 VAPA_1c53020 94cfd7db84eb4e96dd42506552c67eda 286 SUPERFAMILY SSF53328 1 180 2.22E-51 T 12-10-2018 IPR036477 Formyl transferase, N-terminal domain superfamily GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 VAPA_1c53020 94cfd7db84eb4e96dd42506552c67eda 286 Gene3D G3DSA:3.40.50.170 1 182 1.1E-60 T 12-10-2018 VAPA_1c03980 4363d45e37554009be306f2645bd4972 395 SUPERFAMILY SSF51695 34 385 6.28E-76 T 12-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 VAPA_1c03980 4363d45e37554009be306f2645bd4972 395 Gene3D G3DSA:3.20.20.190 34 386 2.5E-118 T 12-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 VAPA_1c03980 4363d45e37554009be306f2645bd4972 395 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 41 381 4.1E-54 T 12-10-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 VAPA_1c10000 482e945950221cb86079a89c19ce2989 181 Pfam PF08534 Redoxin 55 166 1.3E-16 T 12-10-2018 IPR013740 Redoxin GO:0016491 Reactome: R-HSA-3299685|Reactome: R-HSA-5628897 VAPA_1c10000 482e945950221cb86079a89c19ce2989 181 SUPERFAMILY SSF52833 14 174 3.67E-27 T 12-10-2018 IPR036249 Thioredoxin-like superfamily VAPA_1c10000 482e945950221cb86079a89c19ce2989 181 Gene3D G3DSA:3.40.30.10 47 179 6.9E-32 T 12-10-2018 VAPA_1c10000 482e945950221cb86079a89c19ce2989 181 ProSitePatterns PS00194 Thioredoxin family active site. 69 87 - T 12-10-2018 IPR017937 Thioredoxin, conserved site GO:0045454 VAPA_1c10410 f056ad90dc06680fe23caec117e9ee42 258 SUPERFAMILY SSF56784 14 240 2.59E-40 T 12-10-2018 IPR036412 HAD-like superfamily VAPA_1c10410 f056ad90dc06680fe23caec117e9ee42 258 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 15 205 5.1E-17 T 12-10-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 VAPA_1c10410 f056ad90dc06680fe23caec117e9ee42 258 ProSitePatterns PS01228 Hypothetical cof family signature 1. 14 25 - T 12-10-2018 VAPA_1c10410 f056ad90dc06680fe23caec117e9ee42 258 TIGRFAM TIGR00685 T6PP: trehalose-phosphatase 11 239 5.4E-42 T 12-10-2018 IPR003337 Trehalose-phosphatase GO:0003824|GO:0005992 VAPA_1c10410 f056ad90dc06680fe23caec117e9ee42 258 Gene3D G3DSA:3.40.50.1000 15 226 3.9E-51 T 12-10-2018 IPR023214 HAD superfamily VAPA_1c10410 f056ad90dc06680fe23caec117e9ee42 258 Gene3D G3DSA:3.30.70.1020 96 167 3.9E-51 T 12-10-2018 VAPA_1c10410 f056ad90dc06680fe23caec117e9ee42 258 Pfam PF02358 Trehalose-phosphatase 16 219 3.8E-40 T 12-10-2018 IPR003337 Trehalose-phosphatase GO:0003824|GO:0005992 VAPA_1c21520 893e58c4a93da3d09072aa2b3622e7bb 172 Gene3D G3DSA:3.90.950.20 4 165 5.3E-29 T 12-10-2018 IPR036653 CinA-like, C-terminal VAPA_1c21520 893e58c4a93da3d09072aa2b3622e7bb 172 SUPERFAMILY SSF142433 12 164 2.88E-32 T 12-10-2018 IPR036653 CinA-like, C-terminal VAPA_1c21520 893e58c4a93da3d09072aa2b3622e7bb 172 Pfam PF02464 Competence-damaged protein 13 163 2.1E-33 T 12-10-2018 IPR008136 CinA, C-terminal VAPA_2c10490 c4217106abe7c181bfb88553a876da6b 169 SUPERFAMILY SSF51182 48 150 2.12E-5 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily VAPA_2c02740 7bd7fe80bba8e2ede4709157a149938c 321 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 43 316 2.0E-58 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_2c02740 7bd7fe80bba8e2ede4709157a149938c 321 Gene3D G3DSA:3.40.190.150 25 310 3.6E-85 T 12-10-2018 VAPA_2c02740 7bd7fe80bba8e2ede4709157a149938c 321 PIRSF PIRSF017082 1 320 4.2E-62 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_2c02740 7bd7fe80bba8e2ede4709157a149938c 321 SUPERFAMILY SSF53850 104 288 6.51E-6 T 12-10-2018 VAPA_2c02740 7bd7fe80bba8e2ede4709157a149938c 321 Gene3D G3DSA:3.40.190.10 121 245 3.6E-85 T 12-10-2018 VAPA_1c37410 748d3643d7e8a7caccc5c07d9f0225fc 400 SUPERFAMILY SSF111352 7 374 5.89E-95 T 12-10-2018 VAPA_1c37410 748d3643d7e8a7caccc5c07d9f0225fc 400 Gene3D G3DSA:1.10.3430.10 1 399 9.6E-100 T 12-10-2018 IPR029020 Ammonium/urea transporter VAPA_1c37410 748d3643d7e8a7caccc5c07d9f0225fc 400 Pfam PF00909 Ammonium Transporter Family 12 390 4.2E-88 T 12-10-2018 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 VAPA_1c37410 748d3643d7e8a7caccc5c07d9f0225fc 400 ProSitePatterns PS01219 Ammonium transporters signature. 156 181 - T 12-10-2018 IPR018047 Ammonium transporter, conserved site GO:0008519|GO:0016020|GO:0072488 VAPA_1c44590 eba3409730ca8d7916f55225effaced8 337 Gene3D G3DSA:3.15.30.10 27 326 2.2E-110 T 12-10-2018 VAPA_1c44590 eba3409730ca8d7916f55225effaced8 337 Gene3D G3DSA:3.30.1930.10 155 279 2.2E-110 T 12-10-2018 VAPA_1c44590 eba3409730ca8d7916f55225effaced8 337 Pfam PF03864 Phage major capsid protein E 4 335 1.1E-81 T 12-10-2018 IPR005564 Major capsid protein GpE VAPA_1c17610 ee025551e5282b90c1da368768415863 127 Gene3D G3DSA:3.40.30.10 10 103 1.5E-16 T 12-10-2018 VAPA_1c17610 ee025551e5282b90c1da368768415863 127 Pfam PF00085 Thioredoxin 15 77 1.7E-12 T 12-10-2018 IPR013766 Thioredoxin domain GO:0045454 VAPA_1c17610 ee025551e5282b90c1da368768415863 127 SUPERFAMILY SSF52833 15 95 4.59E-20 T 12-10-2018 IPR036249 Thioredoxin-like superfamily VAPA_1c50130 81bae6b0ad49386ef0870dc95d75af82 180 SUPERFAMILY SSF50475 24 175 1.91E-45 T 12-10-2018 VAPA_1c50130 81bae6b0ad49386ef0870dc95d75af82 180 Hamap MF_00833 FMN reductase (NADH) RutF [rutF]. 17 180 45.074 T 12-10-2018 IPR019917 FMN reductase (NADH) RutF GO:0008752|GO:0055114 KEGG: 00740+1.5.1.42|MetaCyc: PWY-7723 VAPA_1c50130 81bae6b0ad49386ef0870dc95d75af82 180 Pfam PF01613 Flavin reductase like domain 29 175 2.3E-33 T 12-10-2018 IPR002563 Flavin reductase like domain GO:0010181 VAPA_1c50130 81bae6b0ad49386ef0870dc95d75af82 180 SMART SM00903 29 174 6.3E-53 T 12-10-2018 IPR002563 Flavin reductase like domain GO:0010181 VAPA_1c50130 81bae6b0ad49386ef0870dc95d75af82 180 TIGRFAM TIGR03615 RutF: pyrimidine utilization flavin reductase protein F 22 174 3.2E-79 T 12-10-2018 IPR019917 FMN reductase (NADH) RutF GO:0008752|GO:0055114 KEGG: 00740+1.5.1.42|MetaCyc: PWY-7723 VAPA_1c50130 81bae6b0ad49386ef0870dc95d75af82 180 Gene3D G3DSA:2.30.110.10 16 177 4.2E-45 T 12-10-2018 IPR012349 FMN-binding split barrel GO:0048037 VAPA_1c02910 e77e99ef18b888fb629cffaef659ba83 329 SUPERFAMILY SSF53850 128 283 1.09E-6 T 12-10-2018 VAPA_1c02910 e77e99ef18b888fb629cffaef659ba83 329 Gene3D G3DSA:3.40.190.10 128 253 1.1E-86 T 12-10-2018 VAPA_1c02910 e77e99ef18b888fb629cffaef659ba83 329 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 51 324 4.7E-61 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c02910 e77e99ef18b888fb629cffaef659ba83 329 Gene3D G3DSA:3.40.190.150 35 318 1.1E-86 T 12-10-2018 VAPA_1c02910 e77e99ef18b888fb629cffaef659ba83 329 PIRSF PIRSF017082 1 328 6.6E-61 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c01090 220305860daef9f7e056b64f86cf5cd0 256 SUPERFAMILY SSF161098 54 236 2.35E-26 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c01090 220305860daef9f7e056b64f86cf5cd0 256 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 79 252 6.5E-19 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 VAPA_1c01090 220305860daef9f7e056b64f86cf5cd0 256 Gene3D G3DSA:1.10.3720.10 54 251 1.3E-24 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c12670 a0a651e8e577b71cd67c21740652c4e5 337 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 170 181 4.0E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c12670 a0a651e8e577b71cd67c21740652c4e5 337 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 222 230 4.0E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c12670 a0a651e8e577b71cd67c21740652c4e5 337 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 242 261 4.0E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c12670 a0a651e8e577b71cd67c21740652c4e5 337 Gene3D G3DSA:3.40.50.720 52 334 1.4E-84 T 12-10-2018 VAPA_1c12670 a0a651e8e577b71cd67c21740652c4e5 337 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 103 332 6.4E-57 T 12-10-2018 VAPA_1c12670 a0a651e8e577b71cd67c21740652c4e5 337 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 229 257 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 VAPA_1c12670 a0a651e8e577b71cd67c21740652c4e5 337 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 216 232 2.3E-34 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c12670 a0a651e8e577b71cd67c21740652c4e5 337 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 170 181 2.3E-34 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c12670 a0a651e8e577b71cd67c21740652c4e5 337 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 263 280 2.3E-34 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c12670 a0a651e8e577b71cd67c21740652c4e5 337 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 242 261 2.3E-34 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c12670 a0a651e8e577b71cd67c21740652c4e5 337 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 95 112 2.3E-34 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c12670 a0a651e8e577b71cd67c21740652c4e5 337 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 297 317 2.3E-34 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c12670 a0a651e8e577b71cd67c21740652c4e5 337 SUPERFAMILY SSF51735 93 332 3.66E-76 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c20270 82a6c3e5bac7264217c8c3eef6eea545 890 Gene3D G3DSA:1.25.40.10 449 812 1.8E-28 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 VAPA_1c20270 82a6c3e5bac7264217c8c3eef6eea545 890 SUPERFAMILY SSF52540 42 243 8.5E-12 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c20270 82a6c3e5bac7264217c8c3eef6eea545 890 Pfam PF00196 Bacterial regulatory proteins, luxR family 825 879 2.0E-13 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_1c20270 82a6c3e5bac7264217c8c3eef6eea545 890 Gene3D G3DSA:1.10.10.10 814 888 3.6E-17 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c20270 82a6c3e5bac7264217c8c3eef6eea545 890 SMART SM00421 823 880 1.0E-17 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_1c20270 82a6c3e5bac7264217c8c3eef6eea545 890 Gene3D G3DSA:3.40.50.300 14 179 1.1E-7 T 12-10-2018 VAPA_1c20270 82a6c3e5bac7264217c8c3eef6eea545 890 SUPERFAMILY SSF46894 816 886 6.8E-17 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 VAPA_1c20270 82a6c3e5bac7264217c8c3eef6eea545 890 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 840 856 4.3E-7 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_1c20270 82a6c3e5bac7264217c8c3eef6eea545 890 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 826 840 4.3E-7 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_1c20270 82a6c3e5bac7264217c8c3eef6eea545 890 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 856 868 4.3E-7 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_2c03630 b1ec18d271a5660f04f3ec87ef78a1b9 234 SMART SM00382 26 213 9.6E-8 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_2c03630 b1ec18d271a5660f04f3ec87ef78a1b9 234 Gene3D G3DSA:3.40.50.300 1 234 1.8E-56 T 12-10-2018 VAPA_2c03630 b1ec18d271a5660f04f3ec87ef78a1b9 234 Pfam PF00005 ABC transporter 17 162 1.3E-25 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_2c03630 b1ec18d271a5660f04f3ec87ef78a1b9 234 SUPERFAMILY SSF52540 2 232 3.8E-55 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_2c03630 b1ec18d271a5660f04f3ec87ef78a1b9 234 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_2c12790 c11a2611bc6e4a16cecd9733055fc335 126 Gene3D G3DSA:3.40.190.290 5 110 1.3E-10 T 12-10-2018 VAPA_2c12790 c11a2611bc6e4a16cecd9733055fc335 126 SUPERFAMILY SSF53850 7 106 7.06E-6 T 12-10-2018 VAPA_1c18040 1b5597945702819230c01f7a45ed842b 148 Gene3D G3DSA:1.10.10.10 2 131 4.2E-17 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c18040 1b5597945702819230c01f7a45ed842b 148 SUPERFAMILY SSF46785 7 97 4.18E-15 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c18040 1b5597945702819230c01f7a45ed842b 148 Pfam PF12840 Helix-turn-helix domain 12 66 2.9E-6 T 12-10-2018 VAPA_1c05090 b0dcaa1f6b3154bd5a5f596af470cbd4 307 SUPERFAMILY SSF88713 12 296 7.91E-52 T 12-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 VAPA_1c05090 b0dcaa1f6b3154bd5a5f596af470cbd4 307 Gene3D G3DSA:3.20.20.370 14 302 7.6E-61 T 12-10-2018 VAPA_1c05090 b0dcaa1f6b3154bd5a5f596af470cbd4 307 Pfam PF01522 Polysaccharide deacetylase 75 181 1.0E-5 T 12-10-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 VAPA_1c06240 5fc2240f1916857b11bf959ff39cc748 160 SUPERFAMILY SSF141452 2 159 8.63E-53 T 12-10-2018 IPR036624 Hcp1-like superfamily VAPA_1c06240 5fc2240f1916857b11bf959ff39cc748 160 Gene3D G3DSA:2.30.110.20 1 160 8.3E-65 T 12-10-2018 IPR036624 Hcp1-like superfamily VAPA_1c06240 5fc2240f1916857b11bf959ff39cc748 160 Pfam PF05638 Type VI secretion system effector, Hcp 6 135 2.8E-40 T 12-10-2018 IPR008514 Type VI secretion system effector, Hcp VAPA_1c07640 18daed8f8f7f7bdccce3db48e19fd1eb 507 Pfam PF01425 Amidase 28 452 1.8E-94 T 12-10-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 VAPA_1c07640 18daed8f8f7f7bdccce3db48e19fd1eb 507 Gene3D G3DSA:3.90.1300.10 2 474 5.9E-133 T 12-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 VAPA_1c07640 18daed8f8f7f7bdccce3db48e19fd1eb 507 SUPERFAMILY SSF75304 7 463 5.23E-127 T 12-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 VAPA_2c04340 ef506bb8c213a357b4126362a4accaaa 503 Pfam PF13671 AAA domain 324 472 1.0E-30 T 12-10-2018 VAPA_2c04340 ef506bb8c213a357b4126362a4accaaa 503 SUPERFAMILY SSF52540 321 488 1.41E-15 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_2c04340 ef506bb8c213a357b4126362a4accaaa 503 Gene3D G3DSA:3.40.50.300 321 502 4.5E-28 T 12-10-2018 VAPA_2c04340 ef506bb8c213a357b4126362a4accaaa 503 SUPERFAMILY SSF56112 7 296 9.86E-18 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily VAPA_1c28120 55a055d5260b00b2be19703b9f2ab3f0 215 Hamap MF_01077 Ribosome maturation factor RimP [rimP]. 1 191 20.41 T 12-10-2018 IPR003728 Ribosome maturation factor RimP GO:0042274 VAPA_1c28120 55a055d5260b00b2be19703b9f2ab3f0 215 SUPERFAMILY SSF74942 89 136 2.48E-5 T 12-10-2018 IPR036847 Ribosome maturation factor RimP, C-terminal domain superfamily VAPA_1c28120 55a055d5260b00b2be19703b9f2ab3f0 215 Pfam PF02576 RimP N-terminal domain 7 88 6.0E-12 T 12-10-2018 IPR028989 Ribosome maturation factor RimP, N-terminal VAPA_1c28120 55a055d5260b00b2be19703b9f2ab3f0 215 SUPERFAMILY SSF75420 3 88 9.29E-10 T 12-10-2018 IPR035956 RimP, N-terminal domain superfamily VAPA_1c21410 540269fdd9d700c9db2f68c3b8eddad3 259 TIGRFAM TIGR00726 TIGR00726: YfiH family protein 27 257 5.8E-48 T 12-10-2018 IPR003730 Multi-copper polyphenol oxidoreductase VAPA_1c21410 540269fdd9d700c9db2f68c3b8eddad3 259 Pfam PF02578 Multi-copper polyphenol oxidoreductase laccase 21 257 5.8E-77 T 12-10-2018 IPR003730 Multi-copper polyphenol oxidoreductase VAPA_1c21410 540269fdd9d700c9db2f68c3b8eddad3 259 Gene3D G3DSA:3.60.140.10 1 259 5.4E-88 T 12-10-2018 IPR038371 Multi-copper polyphenol oxidoreductase superfamily VAPA_1c21410 540269fdd9d700c9db2f68c3b8eddad3 259 SUPERFAMILY SSF64438 4 257 1.83E-75 T 12-10-2018 IPR011324 Cytotoxic necrotizing factor-like, catalytic VAPA_1c39130 94340b9ce4235e1364c972ebfbd0ebba 229 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 147 191 4.3E-13 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 VAPA_1c39130 94340b9ce4235e1364c972ebfbd0ebba 229 SUPERFAMILY SSF56784 7 216 7.82E-47 T 12-10-2018 IPR036412 HAD-like superfamily VAPA_1c39130 94340b9ce4235e1364c972ebfbd0ebba 229 Gene3D G3DSA:3.40.50.1000 10 200 5.0E-48 T 12-10-2018 IPR023214 HAD superfamily VAPA_1c39130 94340b9ce4235e1364c972ebfbd0ebba 229 Pfam PF13419 Haloacid dehalogenase-like hydrolase 12 191 5.9E-22 T 12-10-2018 VAPA_1c39130 94340b9ce4235e1364c972ebfbd0ebba 229 Gene3D G3DSA:1.10.150.240 23 91 5.0E-48 T 12-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 VAPA_1c30280 269e255402755355ed8642c16153a9c1 213 Hamap MF_00143 UPF0114 protein YqhA [yqhA]. 1 213 80.672 T 12-10-2018 IPR020761 Uncharacterised protein family UPF0114, bacteria VAPA_1c30280 269e255402755355ed8642c16153a9c1 213 Pfam PF03350 Uncharacterized protein family, UPF0114 29 167 1.5E-40 T 12-10-2018 IPR005134 Uncharacterised protein family UPF0114 VAPA_1c20330 d4a9501b614a99a958f20ce06f14412a 352 Gene3D G3DSA:3.20.20.70 10 322 1.3E-65 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 VAPA_1c20330 d4a9501b614a99a958f20ce06f14412a 352 Pfam PF05853 beta-keto acid cleavage enzyme 15 318 2.5E-63 T 12-10-2018 IPR008567 3-keto-5-aminohexanoate cleavage enzyme GO:0016740|GO:0019475 KEGG: 00310+2.3.1.247 VAPA_1c14690 b598292e4c44b9e4f9abf57d60600881 364 Pfam PF04375 HemX, putative uroporphyrinogen-III C-methyltransferase 47 360 9.2E-34 T 12-10-2018 IPR007470 Putative uroporphyrinogen-III C-methyltransferase HemX VAPA_1c06720 d0809927a91938304175bc540438777a 305 Gene3D G3DSA:3.40.190.10 91 289 7.3E-69 T 12-10-2018 VAPA_1c06720 d0809927a91938304175bc540438777a 305 Pfam PF03466 LysR substrate binding domain 88 292 9.6E-48 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_1c06720 d0809927a91938304175bc540438777a 305 SUPERFAMILY SSF46785 5 109 1.17E-20 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c06720 d0809927a91938304175bc540438777a 305 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 63 1.0E-16 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c06720 d0809927a91938304175bc540438777a 305 Gene3D G3DSA:1.10.10.10 3 89 1.1E-26 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c06720 d0809927a91938304175bc540438777a 305 Gene3D G3DSA:3.40.190.10 163 264 7.3E-69 T 12-10-2018 VAPA_1c06720 d0809927a91938304175bc540438777a 305 SUPERFAMILY SSF53850 87 297 1.99E-50 T 12-10-2018 VAPA_2c08650 ce9e3c5f9c3cf09395b787a5dd961415 365 Pfam PF01609 Transposase DDE domain 147 351 1.9E-10 T 12-10-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 VAPA_2c08650 ce9e3c5f9c3cf09395b787a5dd961415 365 Pfam PF05598 Transposase domain (DUF772) 56 130 2.9E-22 T 12-10-2018 IPR008490 Transposase InsH, N-terminal VAPA_1c16930 7ca29530edef7f07cd5c6d0e93f8890c 203 Gene3D G3DSA:3.30.530.20 1 157 6.9E-44 T 12-10-2018 IPR023393 START-like domain superfamily VAPA_1c16930 7ca29530edef7f07cd5c6d0e93f8890c 203 SUPERFAMILY SSF55961 1 153 2.59E-39 T 12-10-2018 VAPA_1c16930 7ca29530edef7f07cd5c6d0e93f8890c 203 Pfam PF06240 Carbon monoxide dehydrogenase subunit G (CoxG) 5 151 1.5E-36 T 12-10-2018 IPR010419 Carbon monoxide dehydrogenase subunit G VAPA_1c50860 b427a127e79abd2fea782a59840e2c81 89 SUPERFAMILY SSF50249 9 86 1.63E-28 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold VAPA_1c50860 b427a127e79abd2fea782a59840e2c81 89 ProDom PD001295 RIBOSOMAL S17 30S RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 40S S11 S17P S11 9 78 4.0E-31 T 12-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 VAPA_1c50860 b427a127e79abd2fea782a59840e2c81 89 TIGRFAM TIGR03635 uS17_bact: ribosomal protein uS17 9 79 1.3E-33 T 12-10-2018 IPR019984 30S ribosomal protein S17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 VAPA_1c50860 b427a127e79abd2fea782a59840e2c81 89 PRINTS PR00973 Ribosomal protein S17 family signature 60 70 1.8E-11 T 12-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 VAPA_1c50860 b427a127e79abd2fea782a59840e2c81 89 PRINTS PR00973 Ribosomal protein S17 family signature 70 77 1.8E-11 T 12-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 VAPA_1c50860 b427a127e79abd2fea782a59840e2c81 89 PRINTS PR00973 Ribosomal protein S17 family signature 28 51 1.8E-11 T 12-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 VAPA_1c50860 b427a127e79abd2fea782a59840e2c81 89 Pfam PF00366 Ribosomal protein S17 14 80 2.2E-28 T 12-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 VAPA_1c50860 b427a127e79abd2fea782a59840e2c81 89 ProSitePatterns PS00056 Ribosomal protein S17 signature. 60 72 - T 12-10-2018 IPR019979 Ribosomal protein S17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VAPA_1c50860 b427a127e79abd2fea782a59840e2c81 89 Hamap MF_01345_B 30S ribosomal protein S17 [rpsQ]. 9 84 23.779 T 12-10-2018 IPR019984 30S ribosomal protein S17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 VAPA_1c50860 b427a127e79abd2fea782a59840e2c81 89 Gene3D G3DSA:2.40.50.140 5 88 8.5E-32 T 12-10-2018 VAPA_1c31920 e7eac0c76cfbba5a4b3c69a20d196b01 307 Pfam PF05726 Pirin C-terminal cupin domain 180 278 6.4E-22 T 12-10-2018 IPR008778 Pirin, C-terminal domain Reactome: R-HSA-8935690 VAPA_1c31920 e7eac0c76cfbba5a4b3c69a20d196b01 307 Gene3D G3DSA:2.60.120.10 19 274 1.2E-74 T 12-10-2018 IPR014710 RmlC-like jelly roll fold VAPA_1c31920 e7eac0c76cfbba5a4b3c69a20d196b01 307 SUPERFAMILY SSF51182 19 290 6.03E-78 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily VAPA_1c31920 e7eac0c76cfbba5a4b3c69a20d196b01 307 PIRSF PIRSF006232 4 286 1.9E-87 T 12-10-2018 IPR012093 Pirin Reactome: R-HSA-8935690 VAPA_1c31920 e7eac0c76cfbba5a4b3c69a20d196b01 307 Gene3D G3DSA:2.60.120.10 149 248 1.2E-74 T 12-10-2018 IPR014710 RmlC-like jelly roll fold VAPA_1c31920 e7eac0c76cfbba5a4b3c69a20d196b01 307 Pfam PF02678 Pirin 22 126 6.5E-33 T 12-10-2018 IPR003829 Pirin, N-terminal domain Reactome: R-HSA-8935690 VAPA_2c06830 ae4beab092deecc942516aa1b1b95473 264 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 106 126 - T 12-10-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824 VAPA_2c06830 ae4beab092deecc942516aa1b1b95473 264 Pfam PF00378 Enoyl-CoA hydratase/isomerase 16 259 2.8E-48 T 12-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 VAPA_2c06830 ae4beab092deecc942516aa1b1b95473 264 Gene3D G3DSA:3.90.226.10 8 262 1.0E-59 T 12-10-2018 VAPA_2c06830 ae4beab092deecc942516aa1b1b95473 264 SUPERFAMILY SSF52096 9 259 1.08E-62 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily VAPA_1c49560 4bba9d7d5fad9271ec23f062f41a5dff 125 Pfam PF12779 YXWGXW repeat (2 copies) 52 74 2.8E-6 T 12-10-2018 IPR024447 YXWGXW repeat VAPA_1c49560 4bba9d7d5fad9271ec23f062f41a5dff 125 Pfam PF12779 YXWGXW repeat (2 copies) 80 104 4.1 T 12-10-2018 IPR024447 YXWGXW repeat VAPA_2c05860 c0ff119706ececba4f8a13f83e4a0d95 396 Gene3D G3DSA:3.40.50.10540 3 390 4.2E-116 T 12-10-2018 IPR023606 CoA-transferase family III domain superfamily VAPA_2c05860 c0ff119706ececba4f8a13f83e4a0d95 396 Gene3D G3DSA:3.30.1540.10 234 327 4.2E-116 T 12-10-2018 VAPA_2c05860 c0ff119706ececba4f8a13f83e4a0d95 396 Pfam PF02515 CoA-transferase family III 4 373 6.2E-104 T 12-10-2018 IPR003673 CoA-transferase family III GO:0003824 VAPA_2c05860 c0ff119706ececba4f8a13f83e4a0d95 396 SUPERFAMILY SSF89796 1 396 2.09E-118 T 12-10-2018 IPR023606 CoA-transferase family III domain superfamily VAPA_2c07390 5c005dbd360e73dbdc28247b4409c3fc 223 Gene3D G3DSA:3.50.30.100 4 200 4.8E-50 T 12-10-2018 VAPA_2c07390 5c005dbd360e73dbdc28247b4409c3fc 223 Pfam PF03737 Aldolase/RraA 29 175 1.8E-41 T 12-10-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein VAPA_2c07390 5c005dbd360e73dbdc28247b4409c3fc 223 SUPERFAMILY SSF89562 26 181 8.24E-45 T 12-10-2018 IPR036704 Ribonuclease E inhibitor RraA/RraA-like superfamily VAPA_1c35130 7c7a16c9bab128c2ce70c544ab2a88aa 258 Gene3D G3DSA:3.90.226.10 1 198 1.5E-64 T 12-10-2018 VAPA_1c35130 7c7a16c9bab128c2ce70c544ab2a88aa 258 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 99 119 - T 12-10-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824 VAPA_1c35130 7c7a16c9bab128c2ce70c544ab2a88aa 258 Pfam PF00378 Enoyl-CoA hydratase/isomerase 9 256 7.2E-59 T 12-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 VAPA_1c35130 7c7a16c9bab128c2ce70c544ab2a88aa 258 SUPERFAMILY SSF52096 3 257 1.82E-80 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily VAPA_1c35130 7c7a16c9bab128c2ce70c544ab2a88aa 258 Gene3D G3DSA:1.10.12.10 201 258 2.1E-14 T 12-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal VAPA_1c49720 6c1b774e5f3e4df72d7c69c6465da995 223 Pfam PF10001 Uncharacterized protein conserved in bacteria (DUF2242) 64 186 6.5E-49 T 12-10-2018 IPR018718 Protein of unknown function DUF2242 VAPA_2c05320 5d463e4b3e7ad93166fb10e40f06005a 173 Gene3D G3DSA:3.40.50.12280 19 172 3.5E-48 T 12-10-2018 VAPA_2c05320 5d463e4b3e7ad93166fb10e40f06005a 173 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 54 163 1.8E-26 T 12-10-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VAPA_2c05320 5d463e4b3e7ad93166fb10e40f06005a 173 SUPERFAMILY SSF56770 44 168 4.19E-47 T 12-10-2018 VAPA_1c47070 eea7acf26e2f13b8fea45dffe8dbc7a8 410 Pfam PF13437 HlyD family secretion protein 259 364 4.1E-16 T 12-10-2018 VAPA_1c47070 eea7acf26e2f13b8fea45dffe8dbc7a8 410 Gene3D G3DSA:1.10.287.470 198 259 6.7E-14 T 12-10-2018 VAPA_1c47070 eea7acf26e2f13b8fea45dffe8dbc7a8 410 Gene3D G3DSA:2.40.50.100 75 108 6.4E-8 T 12-10-2018 VAPA_1c47070 eea7acf26e2f13b8fea45dffe8dbc7a8 410 Pfam PF13533 Biotin-lipoyl like 79 111 2.3E-7 T 12-10-2018 IPR039562 Membrane fusion protein, biotin-lipoyl like domain VAPA_1c47070 eea7acf26e2f13b8fea45dffe8dbc7a8 410 SUPERFAMILY SSF111369 79 137 3.27E-5 T 12-10-2018 VAPA_1c47070 eea7acf26e2f13b8fea45dffe8dbc7a8 410 Gene3D G3DSA:2.40.30.170 297 362 6.7E-14 T 12-10-2018 VAPA_1c47070 eea7acf26e2f13b8fea45dffe8dbc7a8 410 Gene3D G3DSA:2.40.50.100 260 296 6.7E-14 T 12-10-2018 VAPA_1c47070 eea7acf26e2f13b8fea45dffe8dbc7a8 410 Gene3D G3DSA:1.10.287.470 109 139 6.4E-8 T 12-10-2018 VAPA_1c47070 eea7acf26e2f13b8fea45dffe8dbc7a8 410 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 375 390 3.2E-33 T 12-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 VAPA_1c47070 eea7acf26e2f13b8fea45dffe8dbc7a8 410 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 305 329 3.2E-33 T 12-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 VAPA_1c47070 eea7acf26e2f13b8fea45dffe8dbc7a8 410 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 87 107 3.2E-33 T 12-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 VAPA_1c47070 eea7acf26e2f13b8fea45dffe8dbc7a8 410 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 272 293 3.2E-33 T 12-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 VAPA_1c47070 eea7acf26e2f13b8fea45dffe8dbc7a8 410 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 45 68 3.2E-33 T 12-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 VAPA_1c47070 eea7acf26e2f13b8fea45dffe8dbc7a8 410 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 329 352 3.2E-33 T 12-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 VAPA_1c47070 eea7acf26e2f13b8fea45dffe8dbc7a8 410 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 390 410 3.2E-33 T 12-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 VAPA_1c13670 6bbd293545d756b4a1c35f5b6008c4bf 245 Pfam PF12686 Protein of unknown function (DUF3800) 7 211 3.4E-27 T 12-10-2018 IPR024524 Protein of unknown function DUF3800 VAPA_1c39730 58d6ec74cc3108b1ce22cdda0bbd88e8 219 Gene3D G3DSA:2.40.128.20 15 190 2.2E-5 T 12-10-2018 IPR012674 Calycin VAPA_1c39730 58d6ec74cc3108b1ce22cdda0bbd88e8 219 SUPERFAMILY SSF50814 20 197 4.15E-24 T 12-10-2018 IPR012674 Calycin VAPA_1c39730 58d6ec74cc3108b1ce22cdda0bbd88e8 219 Pfam PF08768 Domain of unknown function (DUF1794) 21 196 1.5E-19 T 12-10-2018 IPR014878 Domain of unknown function DUF1794 VAPA_1c39730 58d6ec74cc3108b1ce22cdda0bbd88e8 219 PIRSF PIRSF036226 3 200 1.3E-59 T 12-10-2018 IPR014602 Uncharacterised conserved protein UCP036226 VAPA_1c40580 a1d6f042caccc88167380f07d7ad03c2 425 TIGRFAM TIGR00786 dctM: TRAP transporter, DctM subunit 17 419 7.4E-143 T 12-10-2018 IPR004681 TRAP transporter large membrane protein DctM GO:0016021 VAPA_1c40580 a1d6f042caccc88167380f07d7ad03c2 425 PIRSF PIRSF006066 1 425 7.0E-141 T 12-10-2018 IPR004681 TRAP transporter large membrane protein DctM GO:0016021 VAPA_1c40580 a1d6f042caccc88167380f07d7ad03c2 425 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 9 415 9.4E-123 T 12-10-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit VAPA_1c05620 279b333ddb0786541a67aa4d86eb10a2 104 Gene3D G3DSA:3.40.630.30 7 100 5.9E-24 T 12-10-2018 VAPA_1c05620 279b333ddb0786541a67aa4d86eb10a2 104 SUPERFAMILY SSF55729 8 96 3.31E-25 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase VAPA_1c05620 279b333ddb0786541a67aa4d86eb10a2 104 Pfam PF14542 GCN5-related N-acetyl-transferase 16 93 2.7E-23 T 12-10-2018 IPR031165 Yjdj-type Gcn5-related N-acetyltransferase VAPA_1c04970 99a529a5949e4634980b537c1013e492 491 Pfam PF13434 L-lysine 6-monooxygenase (NADPH-requiring) 49 269 6.9E-17 T 12-10-2018 IPR025700 L-lysine 6-monooxygenase/L-ornithine 5-monooxygenase VAPA_1c04970 99a529a5949e4634980b537c1013e492 491 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 52 71 6.9E-8 T 12-10-2018 VAPA_1c04970 99a529a5949e4634980b537c1013e492 491 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 233 251 6.9E-8 T 12-10-2018 VAPA_1c04970 99a529a5949e4634980b537c1013e492 491 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 188 206 6.9E-8 T 12-10-2018 VAPA_1c04970 99a529a5949e4634980b537c1013e492 491 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 233 258 1.3E-10 T 12-10-2018 VAPA_1c04970 99a529a5949e4634980b537c1013e492 491 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 191 200 1.3E-10 T 12-10-2018 VAPA_1c04970 99a529a5949e4634980b537c1013e492 491 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 51 73 1.3E-10 T 12-10-2018 VAPA_1c04970 99a529a5949e4634980b537c1013e492 491 Gene3D G3DSA:3.50.50.60 42 309 3.5E-40 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c04970 99a529a5949e4634980b537c1013e492 491 SUPERFAMILY SSF51905 51 368 3.3E-29 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_2c13110 ecc3ff872a3d7fb2f6d29bb82a169724 365 SUPERFAMILY SSF46785 151 232 5.46E-6 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c22450 9307f48d3a8b993e7106ad5810d900de 303 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 40 269 1.2E-40 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF VAPA_1c22450 9307f48d3a8b993e7106ad5810d900de 303 Gene3D G3DSA:3.40.190.10 132 227 6.9E-82 T 12-10-2018 VAPA_1c22450 9307f48d3a8b993e7106ad5810d900de 303 SUPERFAMILY SSF53850 7 272 1.23E-50 T 12-10-2018 VAPA_1c22450 9307f48d3a8b993e7106ad5810d900de 303 Gene3D G3DSA:3.40.190.10 28 274 6.9E-82 T 12-10-2018 VAPA_1c22450 9307f48d3a8b993e7106ad5810d900de 303 SMART SM00062 38 271 2.0E-41 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF VAPA_1c52170 a73f78a38a217f5d09893d6fecad418b 275 SUPERFAMILY SSF53850 2 242 5.43E-48 T 12-10-2018 VAPA_1c52170 a73f78a38a217f5d09893d6fecad418b 275 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 10 239 2.4E-41 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF VAPA_1c52170 a73f78a38a217f5d09893d6fecad418b 275 SMART SM00062 9 241 2.7E-39 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF VAPA_1c52170 a73f78a38a217f5d09893d6fecad418b 275 Gene3D G3DSA:3.40.190.10 103 198 1.5E-78 T 12-10-2018 VAPA_1c52170 a73f78a38a217f5d09893d6fecad418b 275 Gene3D G3DSA:3.40.190.10 1 244 1.5E-78 T 12-10-2018 VAPA_2c00580 05c2f57f61f7034a640d810d15b4467e 410 Gene3D G3DSA:1.20.1720.10 19 392 4.0E-78 T 12-10-2018 VAPA_2c00580 05c2f57f61f7034a640d810d15b4467e 410 Pfam PF07690 Major Facilitator Superfamily 28 356 2.5E-29 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 VAPA_2c00580 05c2f57f61f7034a640d810d15b4467e 410 SUPERFAMILY SSF103473 12 396 3.4E-54 T 12-10-2018 IPR036259 MFS transporter superfamily VAPA_2c00580 05c2f57f61f7034a640d810d15b4467e 410 PRINTS PR01035 Tetracycline resistance protein signature 283 304 2.0E-5 T 12-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 VAPA_2c00580 05c2f57f61f7034a640d810d15b4467e 410 PRINTS PR01035 Tetracycline resistance protein signature 144 166 2.0E-5 T 12-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 VAPA_2c00580 05c2f57f61f7034a640d810d15b4467e 410 PRINTS PR01035 Tetracycline resistance protein signature 29 45 2.0E-5 T 12-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 VAPA_2c00580 05c2f57f61f7034a640d810d15b4467e 410 PRINTS PR01035 Tetracycline resistance protein signature 59 78 2.0E-5 T 12-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 VAPA_2c11310 7aa103ebb8b05d8dde5b2c25fcbb1bf0 359 TIGRFAM TIGR00180 parB_part: ParB/RepB/Spo0J family partition protein 98 269 1.2E-29 T 12-10-2018 IPR004437 ParB/RepB/Spo0J partition protein family GO:0003677 VAPA_2c11310 7aa103ebb8b05d8dde5b2c25fcbb1bf0 359 Gene3D G3DSA:1.10.10.2830 196 300 9.0E-30 T 12-10-2018 VAPA_2c11310 7aa103ebb8b05d8dde5b2c25fcbb1bf0 359 Gene3D G3DSA:3.90.1530.30 111 175 3.2E-8 T 12-10-2018 VAPA_2c11310 7aa103ebb8b05d8dde5b2c25fcbb1bf0 359 SUPERFAMILY SSF109709 186 279 4.97E-14 T 12-10-2018 VAPA_2c11310 7aa103ebb8b05d8dde5b2c25fcbb1bf0 359 SMART SM00470 96 192 8.9E-12 T 12-10-2018 IPR003115 ParB/Sulfiredoxin VAPA_2c11310 7aa103ebb8b05d8dde5b2c25fcbb1bf0 359 Pfam PF02195 ParB-like nuclease domain 98 191 1.2E-10 T 12-10-2018 IPR003115 ParB/Sulfiredoxin VAPA_2c11310 7aa103ebb8b05d8dde5b2c25fcbb1bf0 359 SUPERFAMILY SSF110849 117 220 1.05E-12 T 12-10-2018 IPR036086 ParB/Sulfiredoxin superfamily VAPA_1c27500 f9ee7938fee4a1e5c7b9ff84bcc7f240 201 SUPERFAMILY SSF52738 12 196 1.29E-55 T 12-10-2018 IPR035909 Methylesterase CheB, C-terminal VAPA_1c27500 f9ee7938fee4a1e5c7b9ff84bcc7f240 201 Pfam PF01339 CheB methylesterase 16 190 6.0E-54 T 12-10-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 VAPA_1c27500 f9ee7938fee4a1e5c7b9ff84bcc7f240 201 Gene3D G3DSA:3.40.50.180 7 200 5.0E-59 T 12-10-2018 IPR035909 Methylesterase CheB, C-terminal VAPA_1c06220 16afcb508dd31bc859d5ed56adea9fa1 178 Gene3D G3DSA:3.40.80.10 21 172 1.1E-14 T 12-10-2018 IPR036505 N-acetylmuramoyl-L-alanine amidase/PGRP domain superfamily GO:0008745|GO:0009253 Reactome: R-HSA-6803157 VAPA_1c06220 16afcb508dd31bc859d5ed56adea9fa1 178 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 35 159 2.3E-12 T 12-10-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 VAPA_1c06220 16afcb508dd31bc859d5ed56adea9fa1 178 SUPERFAMILY SSF55846 35 160 9.42E-16 T 12-10-2018 IPR036505 N-acetylmuramoyl-L-alanine amidase/PGRP domain superfamily GO:0008745|GO:0009253 Reactome: R-HSA-6803157 VAPA_1c32100 3b834064f3763a60b02106bdbf039cd0 299 Pfam PF04909 Amidohydrolase 24 295 2.0E-34 T 12-10-2018 IPR006680 Amidohydrolase-related GO:0016787 VAPA_1c32100 3b834064f3763a60b02106bdbf039cd0 299 SUPERFAMILY SSF51556 20 295 6.81E-70 T 12-10-2018 IPR032466 Metal-dependent hydrolase VAPA_1c32100 3b834064f3763a60b02106bdbf039cd0 299 Gene3D G3DSA:3.20.20.140 12 298 6.6E-79 T 12-10-2018 VAPA_1c39880 7551d0ceda96cedb978bf6a75cbeb826 369 Pfam PF00296 Luciferase-like monooxygenase 21 330 2.6E-79 T 12-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 VAPA_1c39880 7551d0ceda96cedb978bf6a75cbeb826 369 SUPERFAMILY SSF51679 24 361 3.01E-83 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 VAPA_1c39880 7551d0ceda96cedb978bf6a75cbeb826 369 Gene3D G3DSA:3.20.20.30 8 367 1.3E-109 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 VAPA_1c41530 03f8144b8ffc311742ff523a7d956d37 442 Pfam PF13416 Bacterial extracellular solute-binding protein 49 359 1.2E-33 T 12-10-2018 IPR006059 Bacterial extracellular solute-binding protein VAPA_1c41530 03f8144b8ffc311742ff523a7d956d37 442 Gene3D G3DSA:3.40.190.10 149 426 1.9E-107 T 12-10-2018 VAPA_1c41530 03f8144b8ffc311742ff523a7d956d37 442 Gene3D G3DSA:3.40.190.10 35 385 1.9E-107 T 12-10-2018 VAPA_1c41530 03f8144b8ffc311742ff523a7d956d37 442 SUPERFAMILY SSF53850 32 427 2.03E-59 T 12-10-2018 VAPA_1c31810 453182f76bdfa3eeba5ffd85229fe5f4 398 Gene3D G3DSA:3.40.640.10 2 397 1.1E-116 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 VAPA_1c31810 453182f76bdfa3eeba5ffd85229fe5f4 398 SUPERFAMILY SSF53383 2 393 4.08E-102 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase VAPA_1c31810 453182f76bdfa3eeba5ffd85229fe5f4 398 Pfam PF00155 Aminotransferase class I and II 35 389 2.4E-54 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 VAPA_1c31810 453182f76bdfa3eeba5ffd85229fe5f4 398 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 234 247 - T 12-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 VAPA_1c06190 00969e5e626826c47d691183b9a64386 427 SUPERFAMILY SSF48371 108 290 5.76E-11 T 12-10-2018 IPR016024 Armadillo-type fold VAPA_1c06190 00969e5e626826c47d691183b9a64386 427 TIGRFAM TIGR02270 TIGR02270: conserved hypothetical protein 12 417 1.2E-100 T 12-10-2018 IPR011959 Conserved hypothetical protein CHP02270 VAPA_1c06190 00969e5e626826c47d691183b9a64386 427 Gene3D G3DSA:1.25.10.10 101 300 1.9E-7 T 12-10-2018 IPR011989 Armadillo-like helical VAPA_1c06190 00969e5e626826c47d691183b9a64386 427 Pfam PF13646 HEAT repeats 158 227 1.7E-7 T 12-10-2018 VAPA_2c12620 a03eaad2c0fd260d78923728fd0296b6 345 Gene3D G3DSA:3.20.20.70 63 317 3.2E-68 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 VAPA_2c12620 a03eaad2c0fd260d78923728fd0296b6 345 Pfam PF04055 Radical SAM superfamily 101 266 1.5E-12 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 VAPA_2c12620 a03eaad2c0fd260d78923728fd0296b6 345 SUPERFAMILY SSF102114 99 305 1.44E-14 T 12-10-2018 VAPA_2c12620 a03eaad2c0fd260d78923728fd0296b6 345 PIRSF PIRSF006004 1 341 8.8E-88 T 12-10-2018 IPR004383 Ribosomal RNA large subunit methyltransferase RlmN/Cfr GO:0005737|GO:0006364|GO:0008173 VAPA_1c42620 3d2e6ac7c64113f2ab9b5d96a060fa3f 134 Pfam PF00072 Response regulator receiver domain 9 117 1.7E-11 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_1c42620 3d2e6ac7c64113f2ab9b5d96a060fa3f 134 SMART SM00448 5 120 2.5E-8 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_1c42620 3d2e6ac7c64113f2ab9b5d96a060fa3f 134 Gene3D G3DSA:3.40.50.2300 4 131 9.3E-16 T 12-10-2018 VAPA_1c42620 3d2e6ac7c64113f2ab9b5d96a060fa3f 134 SUPERFAMILY SSF52172 6 119 1.07E-17 T 12-10-2018 IPR011006 CheY-like superfamily VAPA_2c01090 53860429b25932b0f95205885f599f31 148 Pfam PF01575 MaoC like domain 32 125 6.7E-19 T 12-10-2018 IPR002539 MaoC-like dehydratase domain VAPA_2c01090 53860429b25932b0f95205885f599f31 148 PRINTS PR01483 Fatty acid synthase signature 34 56 2.1E-5 T 12-10-2018 IPR003965 Fatty acid synthase GO:0004312|GO:0005835|GO:0006633|GO:0055114 VAPA_2c01090 53860429b25932b0f95205885f599f31 148 PRINTS PR01483 Fatty acid synthase signature 56 77 2.1E-5 T 12-10-2018 IPR003965 Fatty acid synthase GO:0004312|GO:0005835|GO:0006633|GO:0055114 VAPA_2c01090 53860429b25932b0f95205885f599f31 148 Gene3D G3DSA:3.10.129.10 7 146 2.3E-33 T 12-10-2018 VAPA_2c01090 53860429b25932b0f95205885f599f31 148 SUPERFAMILY SSF54637 14 148 1.19E-29 T 12-10-2018 IPR029069 HotDog domain superfamily VAPA_1c05670 166948ece98c2d0cb8945548f82793d4 236 Pfam PF11254 Protein of unknown function (DUF3053) 14 230 1.7E-72 T 12-10-2018 IPR021413 Protein of unknown function DUF3053 VAPA_1c49890 5b52fd2dafb83c3b37fa4f99a97bd0e6 504 ProSitePatterns PS00455 Putative AMP-binding domain signature. 157 168 - T 12-10-2018 IPR020845 AMP-binding, conserved site VAPA_1c49890 5b52fd2dafb83c3b37fa4f99a97bd0e6 504 Pfam PF13193 AMP-binding enzyme C-terminal domain 413 487 3.2E-21 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain VAPA_1c49890 5b52fd2dafb83c3b37fa4f99a97bd0e6 504 Gene3D G3DSA:3.30.300.30 398 502 7.1E-31 T 12-10-2018 VAPA_1c49890 5b52fd2dafb83c3b37fa4f99a97bd0e6 504 Gene3D G3DSA:3.40.50.12780 3 397 1.7E-95 T 12-10-2018 VAPA_1c49890 5b52fd2dafb83c3b37fa4f99a97bd0e6 504 SUPERFAMILY SSF56801 4 499 1.31E-135 T 12-10-2018 VAPA_1c49890 5b52fd2dafb83c3b37fa4f99a97bd0e6 504 Pfam PF00501 AMP-binding enzyme 7 403 7.6E-84 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 VAPA_1c08440 3aaa2089c292af160317a2fabf4ebfb8 508 Gene3D G3DSA:3.90.1210.30 3 79 6.5E-20 T 12-10-2018 VAPA_1c08440 3aaa2089c292af160317a2fabf4ebfb8 508 Pfam PF08666 SAF domain 12 77 7.8E-9 T 12-10-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 VAPA_1c08440 3aaa2089c292af160317a2fabf4ebfb8 508 Pfam PF04295 D-galactarate dehydratase / Altronate hydrolase, C terminus 106 506 9.3E-164 T 12-10-2018 IPR007392 D-galactarate/Altronate dehydratase, C-terminal GO:0016829 VAPA_1c08440 3aaa2089c292af160317a2fabf4ebfb8 508 SMART SM00858 11 78 5.9E-10 T 12-10-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 VAPA_1c27630 833c989da4b7e99f0bb6b4079c8d5c02 499 Gene3D G3DSA:3.30.565.10 340 495 2.9E-34 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_1c27630 833c989da4b7e99f0bb6b4079c8d5c02 499 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 385 490 7.7E-19 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase VAPA_1c27630 833c989da4b7e99f0bb6b4079c8d5c02 499 Gene3D G3DSA:1.10.287.130 272 334 1.4E-17 T 12-10-2018 VAPA_1c27630 833c989da4b7e99f0bb6b4079c8d5c02 499 SMART SM00388 267 338 2.9E-6 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 VAPA_1c27630 833c989da4b7e99f0bb6b4079c8d5c02 499 SMART SM00387 382 492 6.0E-29 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase VAPA_1c27630 833c989da4b7e99f0bb6b4079c8d5c02 499 SUPERFAMILY SSF47384 263 329 4.32E-8 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 VAPA_1c27630 833c989da4b7e99f0bb6b4079c8d5c02 499 Pfam PF00512 His Kinase A (phospho-acceptor) domain 267 329 3.0E-10 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 VAPA_1c27630 833c989da4b7e99f0bb6b4079c8d5c02 499 SUPERFAMILY SSF55874 342 491 4.98E-33 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_1c27630 833c989da4b7e99f0bb6b4079c8d5c02 499 PRINTS PR00344 Bacterial sensor protein C-terminal signature 476 489 1.7E-15 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c27630 833c989da4b7e99f0bb6b4079c8d5c02 499 PRINTS PR00344 Bacterial sensor protein C-terminal signature 452 470 1.7E-15 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c27630 833c989da4b7e99f0bb6b4079c8d5c02 499 PRINTS PR00344 Bacterial sensor protein C-terminal signature 423 437 1.7E-15 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c27630 833c989da4b7e99f0bb6b4079c8d5c02 499 PRINTS PR00344 Bacterial sensor protein C-terminal signature 441 451 1.7E-15 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_1c51630 470d15e6338135b2ebd9f150b121f9d3 381 SUPERFAMILY SSF89796 6 364 5.1E-125 T 12-10-2018 IPR023606 CoA-transferase family III domain superfamily VAPA_1c51630 470d15e6338135b2ebd9f150b121f9d3 381 Pfam PF02515 CoA-transferase family III 8 363 3.9E-121 T 12-10-2018 IPR003673 CoA-transferase family III GO:0003824 VAPA_1c51630 470d15e6338135b2ebd9f150b121f9d3 381 Gene3D G3DSA:3.40.50.10540 8 353 4.7E-128 T 12-10-2018 IPR023606 CoA-transferase family III domain superfamily VAPA_1c51630 470d15e6338135b2ebd9f150b121f9d3 381 Gene3D G3DSA:3.30.1540.10 228 319 4.7E-128 T 12-10-2018 VAPA_1c37420 c6f16d52ae577a04b856d67332675ace 299 SMART SM00850 202 299 1.1E-31 T 12-10-2018 IPR007492 LytTR DNA-binding domain GO:0003677 VAPA_1c37420 c6f16d52ae577a04b856d67332675ace 299 Pfam PF04397 LytTr DNA-binding domain 205 296 2.1E-24 T 12-10-2018 IPR007492 LytTR DNA-binding domain GO:0003677 VAPA_1c37420 c6f16d52ae577a04b856d67332675ace 299 Gene3D G3DSA:2.40.50.40 195 261 4.8E-10 T 12-10-2018 VAPA_1c37420 c6f16d52ae577a04b856d67332675ace 299 PIRSF PIRSF031767 12 299 6.6E-75 T 12-10-2018 IPR012379 LytTR MHYE transcriptional regulator, putative VAPA_2c06220 27f8a83f4ab95852cba43f8a7c073ebd 371 TIGRFAM TIGR02551 SpaO_YscQ: type III secretion apparatus protein, YscQ/HrcQ family 65 365 5.7E-34 T 12-10-2018 IPR013385 Type III secretion system apparatus protein YscQ/HrcQ/SpaO GO:0030254 VAPA_2c06220 27f8a83f4ab95852cba43f8a7c073ebd 371 Pfam PF01052 Type III flagellar switch regulator (C-ring) FliN C-term 296 366 3.3E-12 T 12-10-2018 IPR001543 Surface presentation of antigen (SpoA) VAPA_2c06220 27f8a83f4ab95852cba43f8a7c073ebd 371 Gene3D G3DSA:2.30.330.10 283 370 5.0E-22 T 12-10-2018 IPR036429 SpoA-like superfamily VAPA_2c06220 27f8a83f4ab95852cba43f8a7c073ebd 371 Gene3D G3DSA:2.30.330.10 190 250 1.9E-5 T 12-10-2018 IPR036429 SpoA-like superfamily VAPA_2c06220 27f8a83f4ab95852cba43f8a7c073ebd 371 SUPERFAMILY SSF101801 294 367 5.1E-13 T 12-10-2018 IPR036429 SpoA-like superfamily VAPA_1c33170 3ca2231457d3a0a4b0cb28ed287326ac 294 SUPERFAMILY SSF53474 31 293 1.51E-39 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c33170 3ca2231457d3a0a4b0cb28ed287326ac 294 Pfam PF12697 Alpha/beta hydrolase family 54 287 3.8E-14 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 VAPA_1c33170 3ca2231457d3a0a4b0cb28ed287326ac 294 Gene3D G3DSA:3.40.50.1820 12 294 9.8E-41 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c33170 3ca2231457d3a0a4b0cb28ed287326ac 294 PRINTS PR00412 Epoxide hydrolase signature 236 252 1.9E-5 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 VAPA_1c33170 3ca2231457d3a0a4b0cb28ed287326ac 294 PRINTS PR00412 Epoxide hydrolase signature 270 292 1.9E-5 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 VAPA_1c33170 3ca2231457d3a0a4b0cb28ed287326ac 294 PRINTS PR00412 Epoxide hydrolase signature 58 76 1.9E-5 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 VAPA_1c54320 9b7332707e21debee2e0a47459166cb1 324 Gene3D G3DSA:3.40.190.10 126 249 3.2E-94 T 12-10-2018 VAPA_1c54320 9b7332707e21debee2e0a47459166cb1 324 Gene3D G3DSA:3.40.190.150 31 314 3.2E-94 T 12-10-2018 VAPA_1c54320 9b7332707e21debee2e0a47459166cb1 324 PIRSF PIRSF017082 1 324 4.3E-69 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c54320 9b7332707e21debee2e0a47459166cb1 324 SUPERFAMILY SSF53850 111 290 1.27E-13 T 12-10-2018 VAPA_1c54320 9b7332707e21debee2e0a47459166cb1 324 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 48 319 1.1E-73 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c27690 ebf876213ca0e83fe00a0dd1f77e532a 715 Pfam PF07715 TonB-dependent Receptor Plug Domain 70 173 3.2E-16 T 12-10-2018 IPR012910 TonB-dependent receptor, plug domain VAPA_1c27690 ebf876213ca0e83fe00a0dd1f77e532a 715 Gene3D G3DSA:2.40.170.20 186 715 7.5E-102 T 12-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily VAPA_1c27690 ebf876213ca0e83fe00a0dd1f77e532a 715 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 72 715 7.2E-81 T 12-10-2018 IPR010105 TonB-dependent siderophore receptor GO:0005506|GO:0015891|GO:0038023 VAPA_1c27690 ebf876213ca0e83fe00a0dd1f77e532a 715 SUPERFAMILY SSF56935 34 715 1.26E-127 T 12-10-2018 VAPA_1c27690 ebf876213ca0e83fe00a0dd1f77e532a 715 Pfam PF00593 TonB dependent receptor 255 713 5.0E-54 T 12-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel VAPA_1c27690 ebf876213ca0e83fe00a0dd1f77e532a 715 Gene3D G3DSA:2.170.130.10 56 185 4.0E-24 T 12-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily VAPA_1c33910 c58947a5bca933efc6e063cc157fe56a 583 Pfam PF08019 Domain of unknown function (DUF1705) 88 235 2.9E-39 T 12-10-2018 IPR012549 Phosphoethanolamine transferase, N-terminal GO:0016021 VAPA_1c33910 c58947a5bca933efc6e063cc157fe56a 583 SUPERFAMILY SSF53649 263 569 3.27E-20 T 12-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 VAPA_1c33910 c58947a5bca933efc6e063cc157fe56a 583 Gene3D G3DSA:3.40.720.10 255 583 9.5E-77 T 12-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 VAPA_1c33910 c58947a5bca933efc6e063cc157fe56a 583 Pfam PF00884 Sulfatase 266 564 7.9E-40 T 12-10-2018 IPR000917 Sulfatase, N-terminal GO:0008484 VAPA_1c22800 a09b60e7649c26346c098663b16469ed 226 Gene3D G3DSA:3.40.225.10 2 221 2.3E-36 T 12-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily VAPA_1c22800 a09b60e7649c26346c098663b16469ed 226 SUPERFAMILY SSF53639 5 189 2.75E-28 T 12-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily VAPA_1c22800 a09b60e7649c26346c098663b16469ed 226 SMART SM01007 9 181 2.6E-19 T 12-10-2018 IPR001303 Class II aldolase/adducin N-terminal VAPA_1c22800 a09b60e7649c26346c098663b16469ed 226 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 11 180 1.7E-20 T 12-10-2018 IPR001303 Class II aldolase/adducin N-terminal VAPA_1c54210 92912dfece2a789db7d344f911254716 478 SMART SM00487 36 233 1.1E-55 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain VAPA_1c54210 92912dfece2a789db7d344f911254716 478 SUPERFAMILY SSF52540 17 221 8.77E-65 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c54210 92912dfece2a789db7d344f911254716 478 SUPERFAMILY SSF52540 158 366 1.94E-46 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c54210 92912dfece2a789db7d344f911254716 478 Gene3D G3DSA:3.40.50.300 9 223 2.1E-73 T 12-10-2018 VAPA_1c54210 92912dfece2a789db7d344f911254716 478 Pfam PF00270 DEAD/DEAH box helicase 41 207 2.7E-46 T 12-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 VAPA_1c54210 92912dfece2a789db7d344f911254716 478 Gene3D G3DSA:3.40.50.300 224 388 1.3E-36 T 12-10-2018 VAPA_1c54210 92912dfece2a789db7d344f911254716 478 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 165 173 - T 12-10-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site VAPA_1c54210 92912dfece2a789db7d344f911254716 478 SMART SM00490 269 350 3.4E-23 T 12-10-2018 IPR001650 Helicase, C-terminal VAPA_1c54210 92912dfece2a789db7d344f911254716 478 Pfam PF03880 DbpA RNA binding domain 404 474 7.9E-20 T 12-10-2018 IPR005580 DEAD box helicase DbpA/CsdA, RNA-binding domain VAPA_1c54210 92912dfece2a789db7d344f911254716 478 Gene3D G3DSA:3.30.70.330 403 476 1.6E-17 T 12-10-2018 IPR012677 Nucleotide-binding alpha-beta plait domain superfamily VAPA_1c54210 92912dfece2a789db7d344f911254716 478 Pfam PF00271 Helicase conserved C-terminal domain 254 350 4.0E-24 T 12-10-2018 IPR001650 Helicase, C-terminal VAPA_1c50160 2e85a76416c6fdb15f6c13fa6517a356 128 SUPERFAMILY SSF54593 3 126 3.36E-16 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase VAPA_1c50160 2e85a76416c6fdb15f6c13fa6517a356 128 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 4 124 5.9E-6 T 12-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain VAPA_1c50160 2e85a76416c6fdb15f6c13fa6517a356 128 Gene3D G3DSA:3.10.180.10 1 128 1.7E-53 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase VAPA_1c23750 470f2e4d0f5b64b353f1c557e3ce9a54 301 TIGRFAM TIGR01932 hflC: HflC protein 159 287 1.5E-42 T 12-10-2018 IPR010200 HflC GO:0016021|GO:0052547 VAPA_1c23750 470f2e4d0f5b64b353f1c557e3ce9a54 301 SUPERFAMILY SSF117892 54 194 4.45E-21 T 12-10-2018 IPR036013 Band 7/SPFH domain superfamily VAPA_1c23750 470f2e4d0f5b64b353f1c557e3ce9a54 301 Gene3D G3DSA:3.30.479.30 51 190 3.7E-16 T 12-10-2018 VAPA_1c23750 470f2e4d0f5b64b353f1c557e3ce9a54 301 SMART SM00244 20 188 4.2E-17 T 12-10-2018 IPR001107 Band 7 domain VAPA_1c23750 470f2e4d0f5b64b353f1c557e3ce9a54 301 PIRSF PIRSF005651 1 297 8.2E-82 T 12-10-2018 IPR010200 HflC GO:0016021|GO:0052547 VAPA_1c23750 470f2e4d0f5b64b353f1c557e3ce9a54 301 Pfam PF01145 SPFH domain / Band 7 family 24 201 6.0E-27 T 12-10-2018 IPR001107 Band 7 domain VAPA_2c04750 e193bacb11de0d056267e6d77ba55c1c 281 Pfam PF00582 Universal stress protein family 157 279 2.3E-10 T 12-10-2018 IPR006016 UspA VAPA_2c04750 e193bacb11de0d056267e6d77ba55c1c 281 Gene3D G3DSA:3.40.50.12370 5 281 1.6E-37 T 12-10-2018 VAPA_2c04750 e193bacb11de0d056267e6d77ba55c1c 281 SUPERFAMILY SSF52402 157 280 1.67E-20 T 12-10-2018 VAPA_2c04750 e193bacb11de0d056267e6d77ba55c1c 281 PRINTS PR01438 Universal stress protein signature 259 281 1.5E-9 T 12-10-2018 IPR006015 Universal stress protein A VAPA_2c04750 e193bacb11de0d056267e6d77ba55c1c 281 PRINTS PR01438 Universal stress protein signature 3 21 1.5E-9 T 12-10-2018 IPR006015 Universal stress protein A VAPA_2c04750 e193bacb11de0d056267e6d77ba55c1c 281 PRINTS PR01438 Universal stress protein signature 241 253 1.5E-9 T 12-10-2018 IPR006015 Universal stress protein A VAPA_2c04750 e193bacb11de0d056267e6d77ba55c1c 281 SUPERFAMILY SSF52402 1 147 1.26E-15 T 12-10-2018 VAPA_1c37480 27f7eb17c8f1c0b5673ff258e36edcd4 199 Pfam PF04355 SmpA / OmlA family 130 183 5.0E-6 T 12-10-2018 IPR007450 Lipoprotein SmpA/OmlA GO:0019867 VAPA_1c16430 330dafcb30da0b085638e73e02453d4f 299 SUPERFAMILY SSF53474 62 294 3.24E-44 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c16430 330dafcb30da0b085638e73e02453d4f 299 Gene3D G3DSA:3.40.50.1820 57 295 3.3E-59 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c16430 330dafcb30da0b085638e73e02453d4f 299 Pfam PF01738 Dienelactone hydrolase family 73 295 2.1E-63 T 12-10-2018 IPR002925 Dienelactone hydrolase GO:0016787 VAPA_2c08220 94e7ce0bc26f975fd305729bbdf64d82 134 Pfam PF03625 Domain of unknown function DUF302 35 98 1.5E-26 T 12-10-2018 IPR005180 Domain of unknown function DUF302 VAPA_2c08220 94e7ce0bc26f975fd305729bbdf64d82 134 SUPERFAMILY SSF103247 9 124 4.84E-36 T 12-10-2018 IPR035923 TT1751-like domain superfamily VAPA_2c08220 94e7ce0bc26f975fd305729bbdf64d82 134 Gene3D G3DSA:3.30.310.70 4 128 7.0E-46 T 12-10-2018 IPR035923 TT1751-like domain superfamily VAPA_2c08220 94e7ce0bc26f975fd305729bbdf64d82 134 PIRSF PIRSF021774 1 129 2.3E-41 T 12-10-2018 IPR016796 Uncharacterised conserved protein UCP021774 VAPA_2c06410 3c7aba44d97247aa378661debc7dcd0c 111 Pfam PF13358 DDE superfamily endonuclease 1 64 1.4E-12 T 12-10-2018 IPR038717 Tc1-like transposase, DDE domain VAPA_2c11180 e5e99fada5f6d9e261a09718a38aebe8 144 SUPERFAMILY SSF55298 17 127 3.3E-30 T 12-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 VAPA_2c11180 e5e99fada5f6d9e261a09718a38aebe8 144 Gene3D G3DSA:3.30.1330.40 7 131 2.6E-31 T 12-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 VAPA_2c11180 e5e99fada5f6d9e261a09718a38aebe8 144 Pfam PF01042 Endoribonuclease L-PSP 18 126 3.4E-24 T 12-10-2018 IPR006175 YjgF/YER057c/UK114 family Reactome: R-HSA-8849175 VAPA_1c07220 8b6856114c297cb0189e7e370c413366 198 Gene3D G3DSA:3.50.70.10 30 181 7.3E-16 T 12-10-2018 IPR016088 Chalcone isomerase, 3-layer sandwich KEGG: 00941+5.5.1.6|MetaCyc: PWY-2002|MetaCyc: PWY-5059|MetaCyc: PWY-6325|MetaCyc: PWY-6787|MetaCyc: PWY-7397|MetaCyc: PWY-7897 VAPA_1c07220 8b6856114c297cb0189e7e370c413366 198 Pfam PF16036 Chalcone isomerase-like 30 197 8.8E-51 T 12-10-2018 IPR016087 Chalcone isomerase GO:0016872 VAPA_1c07220 8b6856114c297cb0189e7e370c413366 198 SUPERFAMILY SSF54626 28 197 1.03E-18 T 12-10-2018 IPR036298 Chalcone isomerase superfamily GO:0016872 VAPA_1c05310 cfea5827862b437f8732ea2306f35b6c 225 Pfam PF00702 haloacid dehalogenase-like hydrolase 6 183 4.0E-13 T 12-10-2018 VAPA_1c05310 cfea5827862b437f8732ea2306f35b6c 225 Gene3D G3DSA:1.10.150.240 18 95 3.7E-71 T 12-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 VAPA_1c05310 cfea5827862b437f8732ea2306f35b6c 225 Gene3D G3DSA:3.40.50.1000 6 211 3.7E-71 T 12-10-2018 IPR023214 HAD superfamily VAPA_1c05310 cfea5827862b437f8732ea2306f35b6c 225 TIGRFAM TIGR01493 HAD-SF-IA-v2: HAD hydrolase, family IA, variant 2 6 188 2.2E-26 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 VAPA_1c05310 cfea5827862b437f8732ea2306f35b6c 225 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 186 199 5.9E-24 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 VAPA_1c05310 cfea5827862b437f8732ea2306f35b6c 225 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 110 123 5.9E-24 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 VAPA_1c05310 cfea5827862b437f8732ea2306f35b6c 225 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 141 157 5.9E-24 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 VAPA_1c05310 cfea5827862b437f8732ea2306f35b6c 225 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 159 179 5.9E-24 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 VAPA_1c05310 cfea5827862b437f8732ea2306f35b6c 225 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 4 15 5.9E-24 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 VAPA_1c05310 cfea5827862b437f8732ea2306f35b6c 225 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 30 43 5.9E-24 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 VAPA_1c05310 cfea5827862b437f8732ea2306f35b6c 225 TIGRFAM TIGR01428 HAD_type_II: haloacid dehalogenase, type II 6 201 4.3E-64 T 12-10-2018 IPR006328 L-2-Haloacid dehalogenase GO:0019120 KEGG: 00361+3.8.1.2|KEGG: 00625+3.8.1.2|MetaCyc: PWY-7425 VAPA_1c05310 cfea5827862b437f8732ea2306f35b6c 225 SUPERFAMILY SSF56784 6 223 7.8E-45 T 12-10-2018 IPR036412 HAD-like superfamily VAPA_1c16220 63de5f32175b4ccbd63d1c5e23afafb1 383 SUPERFAMILY SSF52172 1 117 1.71E-9 T 12-10-2018 IPR011006 CheY-like superfamily VAPA_1c16220 63de5f32175b4ccbd63d1c5e23afafb1 383 SUPERFAMILY SSF52540 129 366 1.15E-28 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c16220 63de5f32175b4ccbd63d1c5e23afafb1 383 Gene3D G3DSA:3.40.50.2300 1 124 5.0E-33 T 12-10-2018 VAPA_1c16220 63de5f32175b4ccbd63d1c5e23afafb1 383 Pfam PF13614 AAA domain 130 290 6.4E-9 T 12-10-2018 IPR025669 AAA domain VAPA_1c16220 63de5f32175b4ccbd63d1c5e23afafb1 383 Gene3D G3DSA:3.40.50.300 128 366 2.8E-47 T 12-10-2018 VAPA_1c42300 e6f2724f4a721b76af24c23b01ba31b1 216 SUPERFAMILY SSF52833 1 182 1.76E-22 T 12-10-2018 IPR036249 Thioredoxin-like superfamily VAPA_1c42300 e6f2724f4a721b76af24c23b01ba31b1 216 Pfam PF00578 AhpC/TSA family 6 152 7.7E-9 T 12-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 VAPA_1c42300 e6f2724f4a721b76af24c23b01ba31b1 216 Gene3D G3DSA:3.40.30.10 1 175 4.9E-18 T 12-10-2018 VAPA_1c39610 6f497c86c5a53972d161e50761c209cc 139 Gene3D G3DSA:3.10.450.50 2 131 1.2E-31 T 12-10-2018 VAPA_1c39610 6f497c86c5a53972d161e50761c209cc 139 Pfam PF12680 SnoaL-like domain 20 122 1.8E-22 T 12-10-2018 IPR037401 SnoaL-like domain VAPA_1c39610 6f497c86c5a53972d161e50761c209cc 139 SUPERFAMILY SSF54427 17 133 6.54E-29 T 12-10-2018 IPR032710 NTF2-like domain superfamily VAPA_2c04400 efba00c2bdae6d32183701d2c2d12d6b 118 Gene3D G3DSA:3.30.300.130 17 118 6.2E-27 T 12-10-2018 IPR034904 Fe-S cluster assembly domain superfamily VAPA_2c04400 efba00c2bdae6d32183701d2c2d12d6b 118 SUPERFAMILY SSF117916 22 117 2.13E-22 T 12-10-2018 IPR034904 Fe-S cluster assembly domain superfamily VAPA_2c04400 efba00c2bdae6d32183701d2c2d12d6b 118 Pfam PF01883 Iron-sulfur cluster assembly protein 27 88 2.9E-14 T 12-10-2018 IPR002744 MIP18 family-like VAPA_2c05720 acb6ee6976c897cca67a32aed3fc8393 129 SUPERFAMILY SSF46785 16 114 1.71E-30 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_2c05720 acb6ee6976c897cca67a32aed3fc8393 129 Pfam PF01638 HxlR-like helix-turn-helix 26 113 3.3E-28 T 12-10-2018 IPR002577 Helix-turn-helix, HxlR type VAPA_2c05720 acb6ee6976c897cca67a32aed3fc8393 129 Gene3D G3DSA:1.10.10.10 2 122 2.2E-36 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c12360 a3cbeedc081e1da5d103440a7d286a08 126 TIGRFAM TIGR03188 histidine_hisI: phosphoribosyl-ATP diphosphatase 11 101 3.6E-27 T 12-10-2018 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 VAPA_1c12360 a3cbeedc081e1da5d103440a7d286a08 126 Gene3D G3DSA:1.10.287.1080 6 106 1.7E-28 T 12-10-2018 VAPA_1c12360 a3cbeedc081e1da5d103440a7d286a08 126 Hamap MF_01020 Phosphoribosyl-ATP pyrophosphatase [hisE]. 8 101 21.099 T 12-10-2018 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 VAPA_1c12360 a3cbeedc081e1da5d103440a7d286a08 126 Pfam PF01503 Phosphoribosyl-ATP pyrophosphohydrolase 28 104 9.5E-15 T 12-10-2018 IPR021130 Phosphoribosyl-ATP pyrophosphohydrolase-like KEGG: 00340+3.6.1.31 VAPA_1c12360 a3cbeedc081e1da5d103440a7d286a08 126 SUPERFAMILY SSF101386 11 105 1.64E-23 T 12-10-2018 VAPA_1c34590 7e0bb3be0cc5502ff53ff36088519058 193 Pfam PF12802 MarR family 29 84 3.2E-8 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 VAPA_1c34590 7e0bb3be0cc5502ff53ff36088519058 193 PIRSF PIRSF006707 1 179 1.4E-52 T 12-10-2018 IPR026282 DNA-binding protein, MJ1563 type VAPA_1c34590 7e0bb3be0cc5502ff53ff36088519058 193 Gene3D G3DSA:1.10.10.10 8 88 5.5E-25 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c34590 7e0bb3be0cc5502ff53ff36088519058 193 SUPERFAMILY SSF46785 8 153 1.24E-25 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c54540 1ac2024534c28d995b59fe991d68531b 317 Gene3D G3DSA:3.20.10.10 142 311 3.6E-45 T 12-10-2018 VAPA_1c54540 1ac2024534c28d995b59fe991d68531b 317 Pfam PF01063 Amino-transferase class IV 52 280 1.5E-40 T 12-10-2018 IPR001544 Aminotransferase class IV GO:0003824 Reactome: R-HSA-70895 VAPA_1c54540 1ac2024534c28d995b59fe991d68531b 317 SUPERFAMILY SSF56752 25 304 5.49E-65 T 12-10-2018 IPR036038 Aminotransferase-like, PLP-dependent enzymes GO:0003824 Reactome: R-HSA-70895 VAPA_1c54540 1ac2024534c28d995b59fe991d68531b 317 Gene3D G3DSA:3.30.470.10 3 134 9.2E-31 T 12-10-2018 VAPA_1c22470 194e10f06f131549be7572fcd179fa78 228 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 36 227 5.7E-18 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 VAPA_1c22470 194e10f06f131549be7572fcd179fa78 228 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 17 121 1.9E-19 T 12-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 VAPA_1c22470 194e10f06f131549be7572fcd179fa78 228 SUPERFAMILY SSF161098 17 212 1.22E-36 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c22470 194e10f06f131549be7572fcd179fa78 228 Gene3D G3DSA:1.10.3720.10 4 228 3.0E-46 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_2c08300 7ce5254a8f14c21fdba3fb54103fef83 247 SUPERFAMILY SSF46785 164 233 1.01E-14 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_2c08300 7ce5254a8f14c21fdba3fb54103fef83 247 Gene3D G3DSA:1.10.10.10 165 239 9.5E-22 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_2c08300 7ce5254a8f14c21fdba3fb54103fef83 247 Gene3D G3DSA:3.90.79.10 16 164 9.0E-42 T 12-10-2018 VAPA_2c08300 7ce5254a8f14c21fdba3fb54103fef83 247 SUPERFAMILY SSF55811 13 160 2.44E-29 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 VAPA_2c08300 7ce5254a8f14c21fdba3fb54103fef83 247 Pfam PF00293 NUDIX domain 20 148 2.8E-14 T 12-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 VAPA_1c17060 fc10b26de8e5265bca385974b09d86d0 392 Gene3D G3DSA:1.25.40.10 28 295 7.6E-14 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 VAPA_1c17060 fc10b26de8e5265bca385974b09d86d0 392 SUPERFAMILY SSF48452 39 234 1.46E-12 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 VAPA_1c17060 fc10b26de8e5265bca385974b09d86d0 392 Hamap MF_00994 Lipopolysaccharide assembly protein B [lapB]. 7 391 28.873 T 12-10-2018 IPR030865 Lipopolysaccharide assembly protein B GO:0008653 VAPA_1c19170 9e8fa8413c11b6547466dffd6866a2c0 471 Gene3D G3DSA:3.40.50.1100 97 438 3.2E-133 T 12-10-2018 VAPA_1c19170 9e8fa8413c11b6547466dffd6866a2c0 471 TIGRFAM TIGR00260 thrC: threonine synthase 71 432 1.3E-68 T 12-10-2018 IPR004450 Threonine synthase-like VAPA_1c19170 9e8fa8413c11b6547466dffd6866a2c0 471 Gene3D G3DSA:3.90.1380.10 1 90 1.4E-31 T 12-10-2018 IPR037158 Threonine synthase, N-terminal domain superfamily VAPA_1c19170 9e8fa8413c11b6547466dffd6866a2c0 471 Pfam PF14821 Threonine synthase N terminus 2 79 4.9E-30 T 12-10-2018 IPR029144 Threonine synthase, N-terminal VAPA_1c19170 9e8fa8413c11b6547466dffd6866a2c0 471 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 94 334 1.9E-10 T 12-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme VAPA_1c19170 9e8fa8413c11b6547466dffd6866a2c0 471 SUPERFAMILY SSF53686 2 468 3.17E-151 T 12-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme VAPA_1c19170 9e8fa8413c11b6547466dffd6866a2c0 471 Gene3D G3DSA:3.40.50.1100 109 451 3.2E-133 T 12-10-2018 VAPA_2c00330 40d56a817458636ada96e7a313614f99 519 SUPERFAMILY SSF56112 217 427 3.29E-12 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily VAPA_2c00330 40d56a817458636ada96e7a313614f99 519 Pfam PF01636 Phosphotransferase enzyme family 220 402 1.4E-7 T 12-10-2018 IPR002575 Aminoglycoside phosphotransferase VAPA_2c00330 40d56a817458636ada96e7a313614f99 519 SUPERFAMILY SSF53448 21 129 1.26E-5 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases VAPA_2c00060 a2028be7f3dc5a9497d7e68595d44e6c 287 SUPERFAMILY SSF103481 45 143 2.88E-6 T 12-10-2018 VAPA_2c00060 a2028be7f3dc5a9497d7e68595d44e6c 287 SUPERFAMILY SSF103481 193 284 2.75E-10 T 12-10-2018 VAPA_2c00060 a2028be7f3dc5a9497d7e68595d44e6c 287 Pfam PF00892 EamA-like transporter family 151 280 2.6E-6 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 VAPA_2c00060 a2028be7f3dc5a9497d7e68595d44e6c 287 Pfam PF00892 EamA-like transporter family 9 139 5.2E-7 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 VAPA_1c18580 0204361d25a9b31ed7d5ae8ccdd7715c 406 Gene3D G3DSA:3.20.140.10 1 405 4.6E-149 T 12-10-2018 VAPA_1c18580 0204361d25a9b31ed7d5ae8ccdd7715c 406 PIRSF PIRSF000484 1 394 4.2E-64 T 12-10-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 VAPA_1c18580 0204361d25a9b31ed7d5ae8ccdd7715c 406 SUPERFAMILY SSF54675 1 135 6.83E-44 T 12-10-2018 VAPA_1c18580 0204361d25a9b31ed7d5ae8ccdd7715c 406 Hamap MF_00570 Nicotinate phosphoribosyltransferase [pncB]. 1 403 45.358 T 12-10-2018 IPR006406 Nicotinate phosphoribosyltransferase GO:0004516|GO:0019357 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 VAPA_1c18580 0204361d25a9b31ed7d5ae8ccdd7715c 406 SUPERFAMILY SSF51690 116 401 6.08E-83 T 12-10-2018 IPR036068 Nicotinate phosphoribosyltransferase-like, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 VAPA_1c18580 0204361d25a9b31ed7d5ae8ccdd7715c 406 Pfam PF04095 Nicotinate phosphoribosyltransferase (NAPRTase) family 162 402 9.2E-69 T 12-10-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 VAPA_1c18580 0204361d25a9b31ed7d5ae8ccdd7715c 406 TIGRFAM TIGR01514 NAPRTase: nicotinate phosphoribosyltransferase 2 402 5.4E-142 T 12-10-2018 IPR006406 Nicotinate phosphoribosyltransferase GO:0004516|GO:0019357 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 VAPA_1c20030 658bd16314b66f4bf9f4b22600743580 242 Pfam PF17131 Outer membrane lipoprotein-sorting protein 64 236 3.6E-41 T 12-10-2018 IPR033399 Putative outer membrane lipoprotein-sorting protein VAPA_1c20030 658bd16314b66f4bf9f4b22600743580 242 Gene3D G3DSA:2.50.20.10 16 238 4.1E-44 T 12-10-2018 VAPA_1c23820 dac1cfd8114b50ec615597b7afdf0b38 280 Pfam PF12833 Helix-turn-helix domain 190 269 3.2E-17 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 VAPA_1c23820 dac1cfd8114b50ec615597b7afdf0b38 280 Gene3D G3DSA:1.10.10.60 182 273 3.3E-19 T 12-10-2018 VAPA_1c23820 dac1cfd8114b50ec615597b7afdf0b38 280 SMART SM00342 184 268 3.2E-8 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 VAPA_1c23820 dac1cfd8114b50ec615597b7afdf0b38 280 SUPERFAMILY SSF46689 232 270 3.36E-8 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 VAPA_1c19410 6f7e6b746bbc5c8fd9810e84c78946b7 80 ProDom PD000887 CARRIER ACYL PHOSPHOPANTETHEINE ACP ACID FATTY BIOSYNTHESIS LIPID SYNTHESIS CHLOROPLAST 33 68 0.003 T 12-10-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 VAPA_1c19410 6f7e6b746bbc5c8fd9810e84c78946b7 80 Pfam PF00550 Phosphopantetheine attachment site 6 68 2.0E-12 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain VAPA_1c19410 6f7e6b746bbc5c8fd9810e84c78946b7 80 SUPERFAMILY SSF47336 4 72 4.32E-15 T 12-10-2018 IPR036736 ACP-like superfamily VAPA_1c19410 6f7e6b746bbc5c8fd9810e84c78946b7 80 Gene3D G3DSA:1.10.1200.10 5 75 2.9E-17 T 12-10-2018 IPR036736 ACP-like superfamily VAPA_2c04420 79a22391c3bded4ead11d59f8683c50b 770 SUPERFAMILY SSF81442 274 744 6.28E-82 T 12-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 VAPA_2c04420 79a22391c3bded4ead11d59f8683c50b 770 Gene3D G3DSA:1.20.210.10 220 748 8.8E-167 T 12-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 VAPA_2c04420 79a22391c3bded4ead11d59f8683c50b 770 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 279 723 1.6E-68 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 VAPA_1c52120 d8cd26acfa59aac9a43d80212e8e8c9e 387 Pfam PF00480 ROK family 84 280 7.9E-37 T 12-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 VAPA_1c52120 d8cd26acfa59aac9a43d80212e8e8c9e 387 Gene3D G3DSA:1.10.10.10 1 78 2.2E-21 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c52120 d8cd26acfa59aac9a43d80212e8e8c9e 387 SUPERFAMILY SSF46785 8 73 1.29E-14 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c52120 d8cd26acfa59aac9a43d80212e8e8c9e 387 Pfam PF13412 Winged helix-turn-helix DNA-binding 17 56 5.6E-6 T 12-10-2018 VAPA_1c52120 d8cd26acfa59aac9a43d80212e8e8c9e 387 Gene3D G3DSA:3.30.420.40 215 284 5.1E-23 T 12-10-2018 VAPA_1c52120 d8cd26acfa59aac9a43d80212e8e8c9e 387 SUPERFAMILY SSF53067 84 363 1.35E-37 T 12-10-2018 VAPA_1c52120 d8cd26acfa59aac9a43d80212e8e8c9e 387 Gene3D G3DSA:3.30.420.40 285 363 3.4E-8 T 12-10-2018 VAPA_1c52120 d8cd26acfa59aac9a43d80212e8e8c9e 387 Gene3D G3DSA:3.30.420.40 80 214 8.2E-26 T 12-10-2018 VAPA_1c12990 f2b91352a851ef88365f3855618e1a73 259 SUPERFAMILY SSF47240 9 253 1.41E-79 T 12-10-2018 IPR009078 Ferritin-like superfamily VAPA_1c12990 f2b91352a851ef88365f3855618e1a73 259 PIRSF PIRSF037834 2 259 1.6E-98 T 12-10-2018 IPR011882 1,2-phenylacetyl-CoA epoxidase, subunit C GO:0010124 VAPA_1c12990 f2b91352a851ef88365f3855618e1a73 259 Gene3D G3DSA:1.20.1260.10 4 259 1.2E-97 T 12-10-2018 IPR012347 Ferritin-like VAPA_1c12990 f2b91352a851ef88365f3855618e1a73 259 TIGRFAM TIGR02158 PA_CoA_Oxy3: phenylacetate-CoA oxygenase, PaaI subunit 20 259 4.2E-90 T 12-10-2018 IPR011882 1,2-phenylacetyl-CoA epoxidase, subunit C GO:0010124 VAPA_1c12990 f2b91352a851ef88365f3855618e1a73 259 Pfam PF05138 Phenylacetic acid catabolic protein 4 259 3.2E-93 T 12-10-2018 IPR007814 1,2-phenylacetyl-CoA epoxidase, subunit A/C GO:0010124 VAPA_2c05420 d66b16078ccb0334eb6be95c438970c5 493 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 384 410 6.6E-7 T 12-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VAPA_2c05420 d66b16078ccb0334eb6be95c438970c5 493 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 332 351 6.6E-7 T 12-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VAPA_2c05420 d66b16078ccb0334eb6be95c438970c5 493 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 245 269 6.6E-7 T 12-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VAPA_2c05420 d66b16078ccb0334eb6be95c438970c5 493 Pfam PF00361 Proton-conducting membrane transporter 132 423 1.5E-39 T 12-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VAPA_1c01540 15a9ff0e7e45b9c3d63f6bcdeb8c1b01 353 Pfam PF02653 Branched-chain amino acid transport system / permease component 37 328 2.1E-36 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 VAPA_1c01540 15a9ff0e7e45b9c3d63f6bcdeb8c1b01 353 TIGRFAM TIGR03408 urea_trans_UrtC: urea ABC transporter, permease protein UrtC 29 338 1.6E-121 T 12-10-2018 IPR017778 ABC transporter, urea, permease protein, UrtC VAPA_1c53960 805a7cba039fde7aa6c03bef8e031bae 217 Pfam PF00498 FHA domain 24 87 2.8E-17 T 12-10-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 VAPA_1c53960 805a7cba039fde7aa6c03bef8e031bae 217 SMART SM00240 22 72 1.3E-12 T 12-10-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 VAPA_1c53960 805a7cba039fde7aa6c03bef8e031bae 217 SUPERFAMILY SSF49879 8 94 2.1E-24 T 12-10-2018 IPR008984 SMAD/FHA domain superfamily GO:0005515 VAPA_1c53960 805a7cba039fde7aa6c03bef8e031bae 217 Gene3D G3DSA:2.60.200.20 5 108 5.8E-24 T 12-10-2018 VAPA_2c05460 dc3ab3faa031aa316e8bb05795b1df82 65 SUPERFAMILY SSF47598 4 46 6.3E-10 T 12-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 VAPA_2c05460 dc3ab3faa031aa316e8bb05795b1df82 65 Gene3D G3DSA:1.10.1220.10 1 47 1.0E-6 T 12-10-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 VAPA_2c05460 dc3ab3faa031aa316e8bb05795b1df82 65 Pfam PF01402 Ribbon-helix-helix protein, copG family 7 44 7.6E-5 T 12-10-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 VAPA_1c15990 1882bf28395d34ceee74f090ac4a0e86 243 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_1c15990 1882bf28395d34ceee74f090ac4a0e86 243 Gene3D G3DSA:3.40.50.300 2 238 4.1E-58 T 12-10-2018 VAPA_1c15990 1882bf28395d34ceee74f090ac4a0e86 243 Pfam PF00005 ABC transporter 21 165 7.7E-27 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c15990 1882bf28395d34ceee74f090ac4a0e86 243 SMART SM00382 29 214 3.8E-8 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c15990 1882bf28395d34ceee74f090ac4a0e86 243 SUPERFAMILY SSF52540 4 235 1.7E-53 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c33870 7c625d19e7c20c1892e3305e5c8a2af4 114 Pfam PF13560 Helix-turn-helix domain 22 74 6.7E-9 T 12-10-2018 VAPA_1c33870 7c625d19e7c20c1892e3305e5c8a2af4 114 SMART SM00530 25 77 7.0E-4 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 VAPA_1c33870 7c625d19e7c20c1892e3305e5c8a2af4 114 Gene3D G3DSA:1.10.260.40 14 87 2.4E-10 T 12-10-2018 VAPA_1c33870 7c625d19e7c20c1892e3305e5c8a2af4 114 SUPERFAMILY SSF47413 17 73 2.87E-9 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 VAPA_2c12000 ea5c7e8caea72906056a92b20ffcb431 288 Gene3D G3DSA:3.90.1580.10 1 288 2.5E-95 T 12-10-2018 VAPA_2c12000 ea5c7e8caea72906056a92b20ffcb431 288 SUPERFAMILY SSF56436 6 287 2.07E-85 T 12-10-2018 IPR016187 C-type lectin fold VAPA_2c12000 ea5c7e8caea72906056a92b20ffcb431 288 Pfam PF03781 Sulfatase-modifying factor enzyme 1 8 286 7.8E-81 T 12-10-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 VAPA_1c20880 6aeb35556ce8291b2bdb8fc90e436ec4 146 Pfam PF00027 Cyclic nucleotide-binding domain 25 114 4.2E-9 T 12-10-2018 IPR000595 Cyclic nucleotide-binding domain VAPA_1c20880 6aeb35556ce8291b2bdb8fc90e436ec4 146 SMART SM00100 6 129 1.0E-5 T 12-10-2018 IPR000595 Cyclic nucleotide-binding domain VAPA_1c20880 6aeb35556ce8291b2bdb8fc90e436ec4 146 SUPERFAMILY SSF51206 6 136 4.71E-17 T 12-10-2018 IPR018490 Cyclic nucleotide-binding-like VAPA_1c20880 6aeb35556ce8291b2bdb8fc90e436ec4 146 Gene3D G3DSA:2.60.120.10 4 141 1.6E-16 T 12-10-2018 IPR014710 RmlC-like jelly roll fold VAPA_1c13200 cb4aa3e246187a0e8299f1521e77905e 537 Gene3D G3DSA:1.10.246.130 246 357 4.6E-29 T 12-10-2018 VAPA_1c13200 cb4aa3e246187a0e8299f1521e77905e 537 Gene3D G3DSA:3.60.20.40 358 537 1.0E-68 T 12-10-2018 VAPA_1c13200 cb4aa3e246187a0e8299f1521e77905e 537 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 114 132 2.7E-41 T 12-10-2018 VAPA_1c13200 cb4aa3e246187a0e8299f1521e77905e 537 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 230 246 2.7E-41 T 12-10-2018 VAPA_1c13200 cb4aa3e246187a0e8299f1521e77905e 537 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 259 278 2.7E-41 T 12-10-2018 VAPA_1c13200 cb4aa3e246187a0e8299f1521e77905e 537 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 377 395 2.7E-41 T 12-10-2018 VAPA_1c13200 cb4aa3e246187a0e8299f1521e77905e 537 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 353 371 2.7E-41 T 12-10-2018 VAPA_1c13200 cb4aa3e246187a0e8299f1521e77905e 537 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 42 67 2.7E-41 T 12-10-2018 VAPA_1c13200 cb4aa3e246187a0e8299f1521e77905e 537 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 132 151 2.7E-41 T 12-10-2018 VAPA_1c13200 cb4aa3e246187a0e8299f1521e77905e 537 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 432 449 2.7E-41 T 12-10-2018 VAPA_1c13200 cb4aa3e246187a0e8299f1521e77905e 537 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 408 423 2.7E-41 T 12-10-2018 VAPA_1c13200 cb4aa3e246187a0e8299f1521e77905e 537 SUPERFAMILY SSF56235 9 537 1.2E-172 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal VAPA_1c13200 cb4aa3e246187a0e8299f1521e77905e 537 Pfam PF01019 Gamma-glutamyltranspeptidase 35 532 4.9E-149 T 12-10-2018 VAPA_1c33060 bce1c4f6a9608aeba239161c5058f77a 268 SUPERFAMILY SSF52540 50 165 2.34E-26 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c33060 bce1c4f6a9608aeba239161c5058f77a 268 Gene3D G3DSA:3.40.50.300 50 166 1.8E-34 T 12-10-2018 VAPA_1c00810 2a40ab0747f1c0f45acfcbb81d98042c 307 Gene3D G3DSA:3.20.20.70 4 297 7.9E-88 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 VAPA_1c00810 2a40ab0747f1c0f45acfcbb81d98042c 307 Pfam PF05853 beta-keto acid cleavage enzyme 6 294 8.1E-85 T 12-10-2018 IPR008567 3-keto-5-aminohexanoate cleavage enzyme GO:0016740|GO:0019475 KEGG: 00310+2.3.1.247 VAPA_1c01620 4b756968a4799420ce7041edb2aa8f86 166 Pfam PF04972 BON domain 88 150 1.8E-11 T 12-10-2018 IPR007055 BON domain VAPA_1c40130 f7d0311227bd16a62e8b13700008b288 378 Gene3D G3DSA:3.40.50.880 37 266 5.9E-39 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like VAPA_1c40130 f7d0311227bd16a62e8b13700008b288 378 Pfam PF01965 DJ-1/PfpI family 61 223 7.3E-13 T 12-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 VAPA_1c40130 f7d0311227bd16a62e8b13700008b288 378 SUPERFAMILY SSF52317 60 238 1.71E-32 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like VAPA_2c02710 c3769f3da08f8593249699314fbb8a51 283 Gene3D G3DSA:1.10.10.60 179 278 4.3E-19 T 12-10-2018 VAPA_2c02710 c3769f3da08f8593249699314fbb8a51 283 SMART SM00342 195 277 1.5E-15 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 VAPA_2c02710 c3769f3da08f8593249699314fbb8a51 283 SUPERFAMILY SSF46689 232 278 1.03E-5 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 VAPA_2c02710 c3769f3da08f8593249699314fbb8a51 283 Pfam PF12833 Helix-turn-helix domain 201 278 2.3E-16 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 VAPA_2c09580 8d3bb9b80caeae0ef1fec02253a46864 107 Pfam PF11171 Protein of unknown function (DUF2958) 3 104 4.8E-32 T 12-10-2018 IPR021341 Protein of unknown function DUF2958 VAPA_1c52340 b78fdc14b427ad147a070259d913f93d 131 Gene3D G3DSA:3.30.1330.40 8 130 1.0E-31 T 12-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 VAPA_1c52340 b78fdc14b427ad147a070259d913f93d 131 Pfam PF01042 Endoribonuclease L-PSP 15 128 2.1E-21 T 12-10-2018 IPR006175 YjgF/YER057c/UK114 family Reactome: R-HSA-8849175 VAPA_1c52340 b78fdc14b427ad147a070259d913f93d 131 SUPERFAMILY SSF55298 3 130 1.56E-33 T 12-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 VAPA_1c52640 587e896a6cccada20158f9878090a3c6 260 Gene3D G3DSA:3.40.50.720 10 260 2.5E-67 T 12-10-2018 VAPA_1c52640 587e896a6cccada20158f9878090a3c6 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 167 186 9.5E-28 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c52640 587e896a6cccada20158f9878090a3c6 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 188 205 9.5E-28 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c52640 587e896a6cccada20158f9878090a3c6 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 94 105 9.5E-28 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c52640 587e896a6cccada20158f9878090a3c6 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 21 38 9.5E-28 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c52640 587e896a6cccada20158f9878090a3c6 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 223 243 9.5E-28 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c52640 587e896a6cccada20158f9878090a3c6 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 141 157 9.5E-28 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c52640 587e896a6cccada20158f9878090a3c6 260 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 26 260 3.4E-57 T 12-10-2018 VAPA_1c52640 587e896a6cccada20158f9878090a3c6 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 94 105 2.0E-8 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c52640 587e896a6cccada20158f9878090a3c6 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 167 186 2.0E-8 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c52640 587e896a6cccada20158f9878090a3c6 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 147 155 2.0E-8 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c52640 587e896a6cccada20158f9878090a3c6 260 SUPERFAMILY SSF51735 19 260 4.27E-68 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_2c00650 34edfcaaa18768da90df73e487e08872 259 Pfam PF01177 Asp/Glu/Hydantoin racemase 127 240 1.7E-7 T 12-10-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 VAPA_2c00650 34edfcaaa18768da90df73e487e08872 259 PIRSF PIRSF015736 12 259 1.2E-86 T 12-10-2018 IPR026286 Maleate isomerase/Arylmalonate decarboxylase VAPA_2c00650 34edfcaaa18768da90df73e487e08872 259 Gene3D G3DSA:3.40.50.12500 26 259 3.1E-66 T 12-10-2018 VAPA_1c36150 a51ea4f9e93dc16b4972da7a5ab9cd86 417 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 120 417 2.4E-122 T 12-10-2018 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VAPA_1c36150 a51ea4f9e93dc16b4972da7a5ab9cd86 417 ProSitePatterns PS00535 Respiratory chain NADH dehydrogenase 49 Kd subunit signature. 43 54 - T 12-10-2018 IPR014029 NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VAPA_1c36150 a51ea4f9e93dc16b4972da7a5ab9cd86 417 Hamap MF_01358 NAD(P)H-quinone oxidoreductase subunit H, chloroplastic [ndhH]. 1 417 49.86 T 12-10-2018 IPR022885 NAD(P)H-quinone oxidoreductase subunit D/H GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VAPA_1c36150 a51ea4f9e93dc16b4972da7a5ab9cd86 417 TIGRFAM TIGR01962 NuoD: NADH dehydrogenase (quinone), D subunit 6 417 2.2E-183 T 12-10-2018 IPR022885 NAD(P)H-quinone oxidoreductase subunit D/H GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VAPA_1c36150 a51ea4f9e93dc16b4972da7a5ab9cd86 417 SUPERFAMILY SSF56762 16 417 2.88E-136 T 12-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VAPA_1c36150 a51ea4f9e93dc16b4972da7a5ab9cd86 417 Gene3D G3DSA:1.10.645.20 4 417 3.5E-172 T 12-10-2018 IPR038290 NADH-quinone oxidoreductase, subunit D superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VAPA_1c24640 4cdcce4ff6640956073e228d2e098299 864 SUPERFAMILY SSF52540 222 561 8.18E-29 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c24640 4cdcce4ff6640956073e228d2e098299 864 Pfam PF12705 PD-(D/E)XK nuclease superfamily 595 843 1.7E-35 T 12-10-2018 IPR038726 PD-(D/E)XK endonuclease-like domain, AddAB-type VAPA_1c53490 5c9582225685695baea8d09bfad0c488 1401 TIGRFAM TIGR02099 TIGR02099: TIGR02099 family protein 459 1376 8.8E-185 T 12-10-2018 IPR011836 Conserved hypothetical protein CHP02099 VAPA_1c53490 5c9582225685695baea8d09bfad0c488 1401 Pfam PF13116 Protein of unknown function 568 873 7.7E-43 T 12-10-2018 IPR025263 Domain of unknown function DUF3971 VAPA_1c53490 5c9582225685695baea8d09bfad0c488 1401 Pfam PF13502 AsmA-like C-terminal region 1118 1370 6.5E-69 T 12-10-2018 IPR032712 AsmA-like, C-terminal VAPA_1c52240 855db3d73c454ab2a678bebb6c6a8a92 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 15 32 5.1E-40 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c52240 855db3d73c454ab2a678bebb6c6a8a92 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 90 101 5.1E-40 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c52240 855db3d73c454ab2a678bebb6c6a8a92 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 215 235 5.1E-40 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c52240 855db3d73c454ab2a678bebb6c6a8a92 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 162 181 5.1E-40 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c52240 855db3d73c454ab2a678bebb6c6a8a92 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 135 151 5.1E-40 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c52240 855db3d73c454ab2a678bebb6c6a8a92 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 183 200 5.1E-40 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c52240 855db3d73c454ab2a678bebb6c6a8a92 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 90 101 3.7E-11 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c52240 855db3d73c454ab2a678bebb6c6a8a92 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 141 149 3.7E-11 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c52240 855db3d73c454ab2a678bebb6c6a8a92 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 162 181 3.7E-11 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c52240 855db3d73c454ab2a678bebb6c6a8a92 253 SUPERFAMILY SSF51735 13 251 1.06E-77 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c52240 855db3d73c454ab2a678bebb6c6a8a92 253 Gene3D G3DSA:3.40.50.720 7 252 2.4E-80 T 12-10-2018 VAPA_1c52240 855db3d73c454ab2a678bebb6c6a8a92 253 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 22 251 2.8E-62 T 12-10-2018 VAPA_1c52240 855db3d73c454ab2a678bebb6c6a8a92 253 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 14 193 4.3E-5 T 12-10-2018 VAPA_1c25530 02842682ddf959a51da2de7d9d9086bc 306 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 121 304 1.5E-30 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 VAPA_1c25530 02842682ddf959a51da2de7d9d9086bc 306 Gene3D G3DSA:1.10.3720.10 93 300 1.2E-22 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c25530 02842682ddf959a51da2de7d9d9086bc 306 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 27 78 1.6E-12 T 12-10-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain VAPA_1c25530 02842682ddf959a51da2de7d9d9086bc 306 SUPERFAMILY SSF161098 98 288 2.09E-28 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c27150 bbf2bb19444fb83f099d950cc40fa0ed 390 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 23 46 2.4E-5 T 12-10-2018 IPR012902 Prokaryotic N-terminal methylation site VAPA_1c27150 bbf2bb19444fb83f099d950cc40fa0ed 390 Pfam PF16074 Type IV Pilus-assembly protein W 225 382 1.0E-28 T 12-10-2018 IPR032092 Type IV Pilus-assembly protein W GO:0043683 VAPA_1c27150 bbf2bb19444fb83f099d950cc40fa0ed 390 Pfam PF07963 Prokaryotic N-terminal methylation motif 22 46 2.6E-7 T 12-10-2018 IPR012902 Prokaryotic N-terminal methylation site VAPA_1c27150 bbf2bb19444fb83f099d950cc40fa0ed 390 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 24 44 - T 12-10-2018 IPR012902 Prokaryotic N-terminal methylation site VAPA_1c53190 219c2b7f83d83e878b6fe02a09a65335 208 Gene3D G3DSA:1.20.120.80 20 197 5.4E-33 T 12-10-2018 IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle GO:0004129|GO:0016020|GO:0022904 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 VAPA_1c53190 219c2b7f83d83e878b6fe02a09a65335 208 SUPERFAMILY SSF81452 23 195 3.79E-34 T 12-10-2018 IPR035973 Cytochrome c oxidase subunit III-like superfamily GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 VAPA_1c00700 108e24d696cdc632d94d1d85bb926e2e 462 Pfam PF01970 Tripartite tricarboxylate transporter TctA family 18 434 1.6E-40 T 12-10-2018 IPR002823 Protein of unknown function DUF112, transmembrane VAPA_2c08550 f68c74a158b0ef74d50550e5a581af53 173 TIGRFAM TIGR04494 c550_PedF: cytochrome c-550 PedF 28 170 6.9E-60 T 12-10-2018 IPR030991 Cytochrome c-550 PedF VAPA_2c08550 f68c74a158b0ef74d50550e5a581af53 173 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 74 165 1.5E-12 T 12-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 VAPA_2c08550 f68c74a158b0ef74d50550e5a581af53 173 Gene3D G3DSA:1.10.760.10 62 172 1.3E-17 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 VAPA_2c08550 f68c74a158b0ef74d50550e5a581af53 173 SUPERFAMILY SSF46626 30 170 8.29E-17 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 VAPA_1c17040 f1ef014fe8c023ca7fb8289081113b09 322 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 31 305 9.0E-43 T 12-10-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0030288|GO:0055085 VAPA_1c17040 f1ef014fe8c023ca7fb8289081113b09 322 Gene3D G3DSA:3.40.190.170 22 322 1.7E-101 T 12-10-2018 IPR038404 TRAP transporter solute receptor DctP superfamily VAPA_1c32450 59c3397416b968a5fb639efb558dc177 368 Pfam PF13609 Gram-negative porin 7 340 3.9E-59 T 12-10-2018 VAPA_1c32450 59c3397416b968a5fb639efb558dc177 368 SUPERFAMILY SSF56935 20 368 1.83E-58 T 12-10-2018 VAPA_1c32450 59c3397416b968a5fb639efb558dc177 368 Gene3D G3DSA:2.40.160.10 20 368 1.7E-72 T 12-10-2018 IPR023614 Porin domain superfamily VAPA_1c51010 4c6ac029e455457e3d5d8fc9f89e9a24 157 Hamap MF_00480_B 30S ribosomal protein S7 [rpsG]. 1 157 34.904 T 12-10-2018 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 VAPA_1c51010 4c6ac029e455457e3d5d8fc9f89e9a24 157 Pfam PF00177 Ribosomal protein S7p/S5e 1 150 7.0E-64 T 12-10-2018 IPR023798 Ribosomal protein S7 domain VAPA_1c51010 4c6ac029e455457e3d5d8fc9f89e9a24 157 TIGRFAM TIGR01029 rpsG_bact: ribosomal protein uS7 3 156 5.9E-62 T 12-10-2018 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 VAPA_1c51010 4c6ac029e455457e3d5d8fc9f89e9a24 157 ProSitePatterns PS00052 Ribosomal protein S7 signature. 20 46 - T 12-10-2018 IPR020606 Ribosomal protein S7, conserved site GO:0003723|GO:0003735|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 VAPA_1c51010 4c6ac029e455457e3d5d8fc9f89e9a24 157 Gene3D G3DSA:1.10.455.10 2 156 2.5E-57 T 12-10-2018 IPR036823 Ribosomal protein S7 domain superfamily VAPA_1c51010 4c6ac029e455457e3d5d8fc9f89e9a24 157 SUPERFAMILY SSF47973 2 150 4.97E-58 T 12-10-2018 IPR036823 Ribosomal protein S7 domain superfamily VAPA_1c51010 4c6ac029e455457e3d5d8fc9f89e9a24 157 PIRSF PIRSF002122 3 157 7.1E-54 T 12-10-2018 IPR000235 Ribosomal protein S5/S7 GO:0006412 VAPA_1c24190 b2256abade350ec81a6d3c05ec4e2244 280 Gene3D G3DSA:3.40.50.300 16 271 5.8E-60 T 12-10-2018 VAPA_1c24190 b2256abade350ec81a6d3c05ec4e2244 280 Pfam PF00005 ABC transporter 38 179 1.2E-27 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c24190 b2256abade350ec81a6d3c05ec4e2244 280 SMART SM00382 46 230 6.9E-17 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c24190 b2256abade350ec81a6d3c05ec4e2244 280 SUPERFAMILY SSF52540 17 247 6.39E-63 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c34060 df2e1f4baad04347860077cd75722a39 425 PIRSF PIRSF006066 1 425 6.2E-164 T 12-10-2018 IPR004681 TRAP transporter large membrane protein DctM GO:0016021 VAPA_1c34060 df2e1f4baad04347860077cd75722a39 425 TIGRFAM TIGR00786 dctM: TRAP transporter, DctM subunit 17 416 7.0E-134 T 12-10-2018 IPR004681 TRAP transporter large membrane protein DctM GO:0016021 VAPA_1c34060 df2e1f4baad04347860077cd75722a39 425 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 7 414 4.8E-117 T 12-10-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit VAPA_1c27860 a6b50e0ea697d4e7e351f425fb6c02fb 183 Gene3D G3DSA:2.60.120.10 37 172 1.7E-15 T 12-10-2018 IPR014710 RmlC-like jelly roll fold VAPA_1c27860 a6b50e0ea697d4e7e351f425fb6c02fb 183 SUPERFAMILY SSF51182 10 166 4.46E-24 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily VAPA_2c10960 605c1d7415f40920789af41a481cf464 800 Pfam PF00577 Outer membrane usher protein 210 706 2.0E-39 T 12-10-2018 IPR000015 Outer membrane usher protein GO:0009297|GO:0015473|GO:0016020 VAPA_2c10960 605c1d7415f40920789af41a481cf464 800 Gene3D G3DSA:2.60.40.2610 618 710 1.7E-15 T 12-10-2018 VAPA_2c10960 605c1d7415f40920789af41a481cf464 800 Gene3D G3DSA:2.60.40.3110 249 336 1.9E-12 T 12-10-2018 VAPA_1c45370 ee1aa36673577c86c5e5f825739af6a4 219 SUPERFAMILY SSF53182 6 218 7.59E-71 T 12-10-2018 IPR036440 Peptidase C15, pyroglutamyl peptidase I-like superfamily MetaCyc: PWY-7942 VAPA_1c45370 ee1aa36673577c86c5e5f825739af6a4 219 ProSitePatterns PS01333 Pyrrolidone-carboxylate peptidase glutamic acid active site. 72 88 - T 12-10-2018 IPR033693 Pyroglutamyl peptidase I, Glu active site MetaCyc: PWY-7942 VAPA_1c45370 ee1aa36673577c86c5e5f825739af6a4 219 Gene3D G3DSA:3.40.630.20 5 219 6.0E-81 T 12-10-2018 IPR036440 Peptidase C15, pyroglutamyl peptidase I-like superfamily MetaCyc: PWY-7942 VAPA_1c45370 ee1aa36673577c86c5e5f825739af6a4 219 Pfam PF01470 Pyroglutamyl peptidase 6 205 3.0E-80 T 12-10-2018 IPR016125 Peptidase C15, pyroglutamyl peptidase I-like MetaCyc: PWY-7942 VAPA_1c45370 ee1aa36673577c86c5e5f825739af6a4 219 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 65 77 7.2E-46 T 12-10-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 MetaCyc: PWY-7942 VAPA_1c45370 ee1aa36673577c86c5e5f825739af6a4 219 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 135 151 7.2E-46 T 12-10-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 MetaCyc: PWY-7942 VAPA_1c45370 ee1aa36673577c86c5e5f825739af6a4 219 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 166 178 7.2E-46 T 12-10-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 MetaCyc: PWY-7942 VAPA_1c45370 ee1aa36673577c86c5e5f825739af6a4 219 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 83 103 7.2E-46 T 12-10-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 MetaCyc: PWY-7942 VAPA_1c45370 ee1aa36673577c86c5e5f825739af6a4 219 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 7 30 7.2E-46 T 12-10-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 MetaCyc: PWY-7942 VAPA_1c45370 ee1aa36673577c86c5e5f825739af6a4 219 PIRSF PIRSF015592 4 217 5.4E-84 T 12-10-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 MetaCyc: PWY-7942 VAPA_1c45370 ee1aa36673577c86c5e5f825739af6a4 219 ProSitePatterns PS01334 Pyrrolidone-carboxylate peptidase cysteine active site. 133 147 - T 12-10-2018 IPR033694 Pyroglutamyl peptidase I, Cys active site MetaCyc: PWY-7942 VAPA_1c45370 ee1aa36673577c86c5e5f825739af6a4 219 Hamap MF_00417 Pyrrolidone-carboxylate peptidase [pcp]. 5 205 41.367 T 12-10-2018 IPR029762 Pyroglutamyl peptidase I, bacterial-type GO:0005829|GO:0006508|GO:0008234|GO:0016920 MetaCyc: PWY-7942 VAPA_1c45370 ee1aa36673577c86c5e5f825739af6a4 219 TIGRFAM TIGR00504 pyro_pdase: pyroglutamyl-peptidase I 7 219 5.1E-89 T 12-10-2018 IPR029762 Pyroglutamyl peptidase I, bacterial-type GO:0005829|GO:0006508|GO:0008234|GO:0016920 MetaCyc: PWY-7942 VAPA_1c18720 0adb15a6c9cc7f03ea32376e6367e2a8 304 Pfam PF00561 alpha/beta hydrolase fold 30 144 1.4E-17 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 VAPA_1c18720 0adb15a6c9cc7f03ea32376e6367e2a8 304 SUPERFAMILY SSF53474 6 293 2.73E-64 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c18720 0adb15a6c9cc7f03ea32376e6367e2a8 304 Gene3D G3DSA:3.40.50.1820 2 294 7.6E-73 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c25110 8900e0b77e8c2bbb1327d46a891f4dbf 274 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 63 85 - T 12-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 VAPA_1c25110 8900e0b77e8c2bbb1327d46a891f4dbf 274 Pfam PF01066 CDP-alcohol phosphatidyltransferase 22 85 3.9E-14 T 12-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 VAPA_1c25110 8900e0b77e8c2bbb1327d46a891f4dbf 274 TIGRFAM TIGR00473 pssA: CDP-diacylglycerol-serine O-phosphatidyltransferase 28 158 3.3E-35 T 12-10-2018 IPR004533 CDP-diacylglycerol--serine O-phosphatidyltransferase KEGG: 00260+2.7.8.8|KEGG: 00564+2.7.8.8|MetaCyc: PWY-5669 VAPA_1c25110 8900e0b77e8c2bbb1327d46a891f4dbf 274 Gene3D G3DSA:1.20.120.1760 15 162 2.2E-15 T 12-10-2018 VAPA_1c00730 f022de278a1684a89b54dd1a3eb9f219 463 SUPERFAMILY SSF46785 3 71 3.1E-17 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c00730 f022de278a1684a89b54dd1a3eb9f219 463 Pfam PF00392 Bacterial regulatory proteins, gntR family 6 67 5.3E-12 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_1c00730 f022de278a1684a89b54dd1a3eb9f219 463 SUPERFAMILY SSF53383 98 453 2.09E-67 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase VAPA_1c00730 f022de278a1684a89b54dd1a3eb9f219 463 Gene3D G3DSA:3.40.640.10 138 354 9.1E-67 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 VAPA_1c00730 f022de278a1684a89b54dd1a3eb9f219 463 Pfam PF00155 Aminotransferase class I and II 135 446 8.2E-26 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 VAPA_1c00730 f022de278a1684a89b54dd1a3eb9f219 463 SMART SM00345 8 67 1.8E-13 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_1c00730 f022de278a1684a89b54dd1a3eb9f219 463 Gene3D G3DSA:3.90.1150.10 99 453 9.1E-67 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 VAPA_1c00730 f022de278a1684a89b54dd1a3eb9f219 463 Gene3D G3DSA:1.10.10.10 1 68 1.6E-17 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_2c09770 24fc6279deaa97210b05a0ccef6a4db0 325 SUPERFAMILY SSF53850 105 286 8.24E-13 T 12-10-2018 VAPA_2c09770 24fc6279deaa97210b05a0ccef6a4db0 325 PIRSF PIRSF017082 2 323 2.7E-59 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_2c09770 24fc6279deaa97210b05a0ccef6a4db0 325 Gene3D G3DSA:3.40.190.150 38 315 3.6E-85 T 12-10-2018 VAPA_2c09770 24fc6279deaa97210b05a0ccef6a4db0 325 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 53 321 1.0E-65 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_2c09770 24fc6279deaa97210b05a0ccef6a4db0 325 Gene3D G3DSA:3.40.190.10 126 250 3.6E-85 T 12-10-2018 VAPA_1c28320 c9b4476cddf8bc8f9fbe1fa4e98f0e67 124 Gene3D G3DSA:3.40.50.1400 4 124 1.7E-30 T 12-10-2018 VAPA_1c28320 c9b4476cddf8bc8f9fbe1fa4e98f0e67 124 Pfam PF01903 CbiX 14 118 4.7E-25 T 12-10-2018 IPR002762 Cobalamin (vitamin B12) biosynthesis CbiX GO:0009236|GO:0016852 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 VAPA_1c28320 c9b4476cddf8bc8f9fbe1fa4e98f0e67 124 SUPERFAMILY SSF53800 7 121 6.8E-30 T 12-10-2018 VAPA_1c05350 d9fb121bd1b99dd05c92aa61c2da4765 326 Gene3D G3DSA:3.40.190.10 128 251 8.2E-106 T 12-10-2018 VAPA_1c05350 d9fb121bd1b99dd05c92aa61c2da4765 326 Gene3D G3DSA:3.40.190.150 32 316 8.2E-106 T 12-10-2018 VAPA_1c05350 d9fb121bd1b99dd05c92aa61c2da4765 326 SUPERFAMILY SSF53850 117 286 4.21E-17 T 12-10-2018 VAPA_1c05350 d9fb121bd1b99dd05c92aa61c2da4765 326 PIRSF PIRSF017082 3 325 8.5E-83 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c05350 d9fb121bd1b99dd05c92aa61c2da4765 326 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 52 322 1.7E-83 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_2c07090 d2e0ff60b3da0cd80d4889227d3ae37e 449 Gene3D G3DSA:3.90.1300.10 7 447 4.2E-119 T 12-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 VAPA_2c07090 d2e0ff60b3da0cd80d4889227d3ae37e 449 Pfam PF01425 Amidase 37 435 2.3E-80 T 12-10-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 VAPA_2c07090 d2e0ff60b3da0cd80d4889227d3ae37e 449 SUPERFAMILY SSF75304 6 447 2.09E-113 T 12-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 VAPA_2c07090 d2e0ff60b3da0cd80d4889227d3ae37e 449 ProSitePatterns PS00571 Amidases signature. 155 186 - T 12-10-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 VAPA_1c37470 53dcd2e961813062600179f804a83d11 323 Gene3D G3DSA:1.10.1580.10 176 281 5.7E-24 T 12-10-2018 IPR023179 GTP-binding protein, orthogonal bundle domain superfamily VAPA_1c37470 53dcd2e961813062600179f804a83d11 323 Pfam PF01926 50S ribosome-binding GTPase 116 186 1.3E-15 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 VAPA_1c37470 53dcd2e961813062600179f804a83d11 323 PIRSF PIRSF006230 1 283 2.4E-87 T 12-10-2018 IPR016478 GTPase, MTG1 VAPA_1c37470 53dcd2e961813062600179f804a83d11 323 TIGRFAM TIGR03596 GTPase_YlqF: ribosome biogenesis GTP-binding protein YlqF 3 278 1.2E-90 T 12-10-2018 IPR019991 GTP-binding protein, ribosome biogenesis VAPA_1c37470 53dcd2e961813062600179f804a83d11 323 SUPERFAMILY SSF52540 9 185 9.52E-36 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c37470 53dcd2e961813062600179f804a83d11 323 Gene3D G3DSA:3.40.50.300 3 171 5.1E-36 T 12-10-2018 VAPA_1c01660 e4aa7ac08b98e83c3fdcc8ada2baa581 386 SUPERFAMILY SSF53822 43 383 1.18E-52 T 12-10-2018 IPR028082 Periplasmic binding protein-like I VAPA_1c01660 e4aa7ac08b98e83c3fdcc8ada2baa581 386 Gene3D G3DSA:3.40.50.2300 45 374 3.6E-83 T 12-10-2018 VAPA_1c01660 e4aa7ac08b98e83c3fdcc8ada2baa581 386 Gene3D G3DSA:3.40.50.2300 161 378 3.6E-83 T 12-10-2018 VAPA_1c01660 e4aa7ac08b98e83c3fdcc8ada2baa581 386 Pfam PF13458 Periplasmic binding protein 43 378 2.8E-51 T 12-10-2018 IPR028081 Leucine-binding protein domain VAPA_1c50040 eeb3199db524fd53af4f990e3420ce2c 202 SUPERFAMILY SSF46626 94 170 5.01E-15 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 VAPA_1c50040 eeb3199db524fd53af4f990e3420ce2c 202 Gene3D G3DSA:1.10.760.10 88 172 9.5E-25 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 VAPA_1c50040 eeb3199db524fd53af4f990e3420ce2c 202 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 94 168 5.7E-15 T 12-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 VAPA_1c06820 7cc877a5a1505dd280c3f800b675da30 492 Gene3D G3DSA:1.20.1600.10 56 481 4.2E-99 T 12-10-2018 VAPA_1c06820 7cc877a5a1505dd280c3f800b675da30 492 SUPERFAMILY SSF56954 5 481 2.09E-80 T 12-10-2018 VAPA_1c06820 7cc877a5a1505dd280c3f800b675da30 492 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 17 481 1.9E-83 T 12-10-2018 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0016020|GO:0022857|GO:0055085 VAPA_1c06820 7cc877a5a1505dd280c3f800b675da30 492 Pfam PF02321 Outer membrane efflux protein 299 480 1.8E-23 T 12-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 VAPA_1c06820 7cc877a5a1505dd280c3f800b675da30 492 Pfam PF02321 Outer membrane efflux protein 69 255 4.5E-22 T 12-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 VAPA_1c06820 7cc877a5a1505dd280c3f800b675da30 492 Gene3D G3DSA:2.20.200.10 103 372 4.2E-99 T 12-10-2018 VAPA_1c16910 422d15167b6c8c9e356bca6fdebb25d3 300 Gene3D G3DSA:3.40.50.300 20 207 5.6E-29 T 12-10-2018 VAPA_1c16910 422d15167b6c8c9e356bca6fdebb25d3 300 SUPERFAMILY SSF52540 23 278 4.03E-36 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c16910 422d15167b6c8c9e356bca6fdebb25d3 300 SMART SM00382 34 195 6.0E-5 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c16910 422d15167b6c8c9e356bca6fdebb25d3 300 Pfam PF07728 AAA domain (dynein-related subfamily) 37 188 2.5E-16 T 12-10-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 VAPA_1c01490 0f839d05acb5d26e999c2cbd0a59beb3 336 SUPERFAMILY SSF53474 1 313 9.56E-80 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c01490 0f839d05acb5d26e999c2cbd0a59beb3 336 PIRSF PIRSF000443 1 334 2.5E-79 T 12-10-2018 IPR008220 Homoserine/serine acetyltransferase MetX-like GO:0005737|GO:0009058|GO:0016747 VAPA_1c01490 0f839d05acb5d26e999c2cbd0a59beb3 336 Gene3D G3DSA:3.40.50.1820 1 336 2.1E-100 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c01490 0f839d05acb5d26e999c2cbd0a59beb3 336 Pfam PF00561 alpha/beta hydrolase fold 54 153 5.8E-11 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 VAPA_2c01870 0b9ef2c362c62f7ce43907d85eb162a7 581 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 130 140 - T 12-10-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 VAPA_2c01870 0b9ef2c362c62f7ce43907d85eb162a7 581 Gene3D G3DSA:3.50.30.80 383 536 4.5E-48 T 12-10-2018 VAPA_2c01870 0b9ef2c362c62f7ce43907d85eb162a7 581 SUPERFAMILY SSF143975 9 382 1.57E-117 T 12-10-2018 IPR037237 IlvD/EDD, N-terminal domain KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 VAPA_2c01870 0b9ef2c362c62f7ce43907d85eb162a7 581 Pfam PF00920 Dehydratase family 47 562 3.5E-168 T 12-10-2018 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 VAPA_2c01870 0b9ef2c362c62f7ce43907d85eb162a7 581 SUPERFAMILY SSF52016 384 567 1.1E-56 T 12-10-2018 VAPA_1c37750 df9e85afb1cf82ce9a9b3c92143b59e3 250 Pfam PF10014 2OG-Fe dioxygenase 50 241 4.7E-65 T 12-10-2018 IPR018724 2OG-Fe dioxygenase VAPA_1c37750 df9e85afb1cf82ce9a9b3c92143b59e3 250 Gene3D G3DSA:2.60.120.620 8 250 1.6E-84 T 12-10-2018 VAPA_1c16870 4e36f4478e60b02ab4b0150ea037d4b7 378 Pfam PF02954 Bacterial regulatory protein, Fis family 331 368 3.1E-12 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 VAPA_1c16870 4e36f4478e60b02ab4b0150ea037d4b7 378 Gene3D G3DSA:3.30.450.40 28 219 3.4E-41 T 12-10-2018 IPR029016 GAF-like domain superfamily VAPA_1c16870 4e36f4478e60b02ab4b0150ea037d4b7 378 Gene3D G3DSA:1.10.10.60 320 371 3.1E-12 T 12-10-2018 VAPA_1c16870 4e36f4478e60b02ab4b0150ea037d4b7 378 SUPERFAMILY SSF46689 324 368 3.58E-9 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 VAPA_1c16870 4e36f4478e60b02ab4b0150ea037d4b7 378 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 337 354 1.2E-6 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 VAPA_1c16870 4e36f4478e60b02ab4b0150ea037d4b7 378 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 354 374 1.2E-6 T 12-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 VAPA_2c04680 9987a64426ba83c90ffb775263afd1c6 219 Gene3D G3DSA:3.40.50.2020 5 207 2.4E-72 T 12-10-2018 VAPA_2c04680 9987a64426ba83c90ffb775263afd1c6 219 SUPERFAMILY SSF53271 4 211 4.22E-48 T 12-10-2018 IPR029057 Phosphoribosyltransferase-like VAPA_2c04680 9987a64426ba83c90ffb775263afd1c6 219 Pfam PF00156 Phosphoribosyl transferase domain 2 198 8.1E-28 T 12-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 VAPA_2c04680 9987a64426ba83c90ffb775263afd1c6 219 Gene3D G3DSA:3.30.1310.20 55 119 2.4E-72 T 12-10-2018 VAPA_1c20420 07695fa89c473aef6dea0af1891f9881 268 Pfam PF03466 LysR substrate binding domain 62 258 7.0E-22 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_1c20420 07695fa89c473aef6dea0af1891f9881 268 Gene3D G3DSA:3.40.190.10 56 257 9.9E-69 T 12-10-2018 VAPA_1c20420 07695fa89c473aef6dea0af1891f9881 268 Gene3D G3DSA:1.10.10.10 1 52 5.0E-13 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c20420 07695fa89c473aef6dea0af1891f9881 268 Gene3D G3DSA:3.40.190.10 135 233 9.9E-69 T 12-10-2018 VAPA_1c20420 07695fa89c473aef6dea0af1891f9881 268 SUPERFAMILY SSF46785 1 49 2.63E-6 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c20420 07695fa89c473aef6dea0af1891f9881 268 SUPERFAMILY SSF53850 54 260 8.07E-41 T 12-10-2018 VAPA_2c08910 7feeb869f7c1856a3868bb5c330eacfb 307 SUPERFAMILY SSF46785 2 85 9.07E-18 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_2c08910 7feeb869f7c1856a3868bb5c330eacfb 307 SUPERFAMILY SSF53850 89 292 7.6E-37 T 12-10-2018 VAPA_2c08910 7feeb869f7c1856a3868bb5c330eacfb 307 Gene3D G3DSA:1.10.10.10 2 89 3.6E-23 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_2c08910 7feeb869f7c1856a3868bb5c330eacfb 307 Gene3D G3DSA:3.40.190.290 91 293 1.4E-55 T 12-10-2018 VAPA_2c08910 7feeb869f7c1856a3868bb5c330eacfb 307 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 62 2.5E-14 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_2c08910 7feeb869f7c1856a3868bb5c330eacfb 307 Pfam PF03466 LysR substrate binding domain 88 291 7.7E-34 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_1c52260 f845d2bd1f129023813de83b6b441f36 338 PIRSF PIRSF017082 2 337 1.9E-80 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c52260 f845d2bd1f129023813de83b6b441f36 338 Gene3D G3DSA:3.40.190.10 133 263 1.3E-111 T 12-10-2018 VAPA_1c52260 f845d2bd1f129023813de83b6b441f36 338 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 54 333 2.5E-89 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c52260 f845d2bd1f129023813de83b6b441f36 338 Gene3D G3DSA:3.40.190.150 35 328 1.3E-111 T 12-10-2018 VAPA_1c52260 f845d2bd1f129023813de83b6b441f36 338 SUPERFAMILY SSF53850 122 295 6.21E-9 T 12-10-2018 VAPA_1c34290 1923e8d318e5b7d79cc3bce01f971395 426 PIRSF PIRSF006066 1 426 1.4E-141 T 12-10-2018 IPR004681 TRAP transporter large membrane protein DctM GO:0016021 VAPA_1c34290 1923e8d318e5b7d79cc3bce01f971395 426 TIGRFAM TIGR00786 dctM: TRAP transporter, DctM subunit 17 419 9.3E-152 T 12-10-2018 IPR004681 TRAP transporter large membrane protein DctM GO:0016021 VAPA_1c34290 1923e8d318e5b7d79cc3bce01f971395 426 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 7 415 1.6E-120 T 12-10-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit VAPA_1c40040 6b7edb5142e1dfe60b42a4a7edea308e 268 SMART SM00342 165 247 9.7E-12 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 VAPA_1c40040 6b7edb5142e1dfe60b42a4a7edea308e 268 Pfam PF12833 Helix-turn-helix domain 171 244 7.1E-15 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 VAPA_1c40040 6b7edb5142e1dfe60b42a4a7edea308e 268 Gene3D G3DSA:1.10.10.60 148 248 9.7E-18 T 12-10-2018 VAPA_1c40040 6b7edb5142e1dfe60b42a4a7edea308e 268 SUPERFAMILY SSF46689 211 249 2.78E-6 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 VAPA_1c30160 2e3a91ee03fdf9ea2546d61790c56cde 494 Pfam PF17408 Malonyl-CoA decarboxylase N-terminal domain 118 205 2.1E-23 T 12-10-2018 IPR035372 Malonyl-CoA decarboxylase, N-terminal KEGG: 00410+4.1.1.9|KEGG: 00640+4.1.1.9|Reactome: R-HSA-390247|Reactome: R-HSA-9033241 VAPA_1c30160 2e3a91ee03fdf9ea2546d61790c56cde 494 Gene3D G3DSA:3.40.630.150 207 493 3.6E-102 T 12-10-2018 VAPA_1c30160 2e3a91ee03fdf9ea2546d61790c56cde 494 Gene3D G3DSA:1.20.140.90 64 206 1.4E-30 T 12-10-2018 IPR038351 Malonyl-CoA decarboxylase, N-terminal domain superfamily KEGG: 00410+4.1.1.9|KEGG: 00640+4.1.1.9|Reactome: R-HSA-390247|Reactome: R-HSA-9033241 VAPA_1c30160 2e3a91ee03fdf9ea2546d61790c56cde 494 Pfam PF05292 Malonyl-CoA decarboxylase C-terminal domain 208 464 1.9E-104 T 12-10-2018 IPR007956 Malonyl-CoA decarboxylase, C-terminal GO:0006633|GO:0050080 KEGG: 00410+4.1.1.9|KEGG: 00640+4.1.1.9|Reactome: R-HSA-390247|Reactome: R-HSA-9033241 VAPA_1c01720 40093380c7a95340714d1d21675a754e 107 Gene3D G3DSA:3.10.20.30 1 107 1.4E-32 T 12-10-2018 IPR012675 Beta-grasp domain superfamily VAPA_1c01720 40093380c7a95340714d1d21675a754e 107 SUPERFAMILY SSF54292 3 105 2.27E-30 T 12-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 VAPA_1c01720 40093380c7a95340714d1d21675a754e 107 PRINTS PR00355 Adrenodoxin signature 83 91 4.5E-7 T 12-10-2018 IPR001055 Adrenodoxin GO:0009055|GO:0051537 Reactome: R-HSA-1362409|Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 VAPA_1c01720 40093380c7a95340714d1d21675a754e 107 PRINTS PR00355 Adrenodoxin signature 40 50 4.5E-7 T 12-10-2018 IPR001055 Adrenodoxin GO:0009055|GO:0051537 Reactome: R-HSA-1362409|Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 VAPA_1c01720 40093380c7a95340714d1d21675a754e 107 PRINTS PR00355 Adrenodoxin signature 59 73 4.5E-7 T 12-10-2018 IPR001055 Adrenodoxin GO:0009055|GO:0051537 Reactome: R-HSA-1362409|Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 VAPA_1c01720 40093380c7a95340714d1d21675a754e 107 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 9 92 2.9E-11 T 12-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 VAPA_1c43410 1171a753cbdc77219d0b83fc0003baae 538 SMART SM00283 263 510 2.5E-92 T 12-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 VAPA_1c43410 1171a753cbdc77219d0b83fc0003baae 538 Pfam PF00672 HAMP domain 210 253 5.3E-9 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 VAPA_1c43410 1171a753cbdc77219d0b83fc0003baae 538 Pfam PF12729 Four helix bundle sensory module for signal transduction 3 171 2.9E-21 T 12-10-2018 IPR024478 Chemotaxis methyl-accepting receptor HlyB-like, 4HB MCP domain VAPA_1c43410 1171a753cbdc77219d0b83fc0003baae 538 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 322 478 1.1E-54 T 12-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 VAPA_1c43410 1171a753cbdc77219d0b83fc0003baae 538 SUPERFAMILY SSF58104 230 511 2.09E-76 T 12-10-2018 VAPA_1c43410 1171a753cbdc77219d0b83fc0003baae 538 Gene3D G3DSA:1.10.287.950 209 512 3.0E-95 T 12-10-2018 VAPA_1c43410 1171a753cbdc77219d0b83fc0003baae 538 SMART SM00304 210 262 7.8E-10 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 VAPA_1c43410 1171a753cbdc77219d0b83fc0003baae 538 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 284 313 1.8E-57 T 12-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 VAPA_1c43410 1171a753cbdc77219d0b83fc0003baae 538 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 361 388 1.8E-57 T 12-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 VAPA_1c43410 1171a753cbdc77219d0b83fc0003baae 538 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 390 419 1.8E-57 T 12-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 VAPA_1c43410 1171a753cbdc77219d0b83fc0003baae 538 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 438 467 1.8E-57 T 12-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 VAPA_1c49530 380f2dcbfd4d555fffd812ecbd2eb122 276 SUPERFAMILY SSF159501 31 263 7.85E-52 T 12-10-2018 VAPA_1c49530 380f2dcbfd4d555fffd812ecbd2eb122 276 Pfam PF04187 Haem-binding uptake, Tiki superfamily, ChaN 43 229 3.1E-32 T 12-10-2018 IPR007314 Haem-binding uptake, Tiki superfamily, ChaN VAPA_1c49530 380f2dcbfd4d555fffd812ecbd2eb122 276 Gene3D G3DSA:3.40.50.11550 44 231 1.6E-34 T 12-10-2018 VAPA_1c49530 380f2dcbfd4d555fffd812ecbd2eb122 276 Gene3D G3DSA:1.10.8.760 141 194 1.6E-34 T 12-10-2018 VAPA_1c11850 bbf728126f116f3ef7bea1423fb1977b 212 Pfam PF01381 Helix-turn-helix 33 86 4.4E-13 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 VAPA_1c11850 bbf728126f116f3ef7bea1423fb1977b 212 SUPERFAMILY SSF47413 25 90 2.6E-15 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 VAPA_1c11850 bbf728126f116f3ef7bea1423fb1977b 212 SMART SM00530 32 87 2.9E-13 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 VAPA_1c11850 bbf728126f116f3ef7bea1423fb1977b 212 SUPERFAMILY SSF51182 95 208 6.29E-25 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily VAPA_1c11850 bbf728126f116f3ef7bea1423fb1977b 212 Pfam PF07883 Cupin domain 138 206 1.4E-11 T 12-10-2018 IPR013096 Cupin 2, conserved barrel VAPA_1c11850 bbf728126f116f3ef7bea1423fb1977b 212 Gene3D G3DSA:1.10.260.40 28 93 8.3E-16 T 12-10-2018 VAPA_1c11850 bbf728126f116f3ef7bea1423fb1977b 212 Gene3D G3DSA:2.60.120.10 100 206 2.9E-15 T 12-10-2018 IPR014710 RmlC-like jelly roll fold VAPA_1c00580 fe5714ee91369f33e23cda8d69990a99 146 ProDom PD456999 SIGNAL PRECURSOR TRANSMEMBRANE MEMBRANE YOHN INTEGRAL EXPORTED SIMILAR LIPOPROTEIN LIPOPROTEIN 86 141 1.0E-14 T 12-10-2018 IPR024572 Nickel/cobalt homeostasis protein RcnB VAPA_1c00580 fe5714ee91369f33e23cda8d69990a99 146 Gene3D G3DSA:3.10.450.160 70 146 2.6E-22 T 12-10-2018 VAPA_1c00580 fe5714ee91369f33e23cda8d69990a99 146 Pfam PF11776 Nickel/cobalt transporter regulator 90 140 9.7E-25 T 12-10-2018 IPR024572 Nickel/cobalt homeostasis protein RcnB VAPA_1c51680 1c78cb68237d2e4f0e0a078c6a61caab 309 Gene3D G3DSA:1.10.10.10 3 87 6.7E-26 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c51680 1c78cb68237d2e4f0e0a078c6a61caab 309 SUPERFAMILY SSF53850 92 306 4.34E-38 T 12-10-2018 VAPA_1c51680 1c78cb68237d2e4f0e0a078c6a61caab 309 SUPERFAMILY SSF46785 5 86 4.69E-22 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c51680 1c78cb68237d2e4f0e0a078c6a61caab 309 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 1.2E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c51680 1c78cb68237d2e4f0e0a078c6a61caab 309 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 1.2E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c51680 1c78cb68237d2e4f0e0a078c6a61caab 309 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 1.2E-6 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c51680 1c78cb68237d2e4f0e0a078c6a61caab 309 Pfam PF03466 LysR substrate binding domain 91 302 4.1E-36 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_1c51680 1c78cb68237d2e4f0e0a078c6a61caab 309 Gene3D G3DSA:3.40.190.290 92 302 8.3E-58 T 12-10-2018 VAPA_1c51680 1c78cb68237d2e4f0e0a078c6a61caab 309 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 63 6.1E-18 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c06990 c9d1e76a08e2442a62d09ef64abfd222 378 SUPERFAMILY SSF51182 25 369 7.86E-88 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily VAPA_1c06990 c9d1e76a08e2442a62d09ef64abfd222 378 Pfam PF07883 Cupin domain 111 178 1.1E-17 T 12-10-2018 IPR013096 Cupin 2, conserved barrel VAPA_1c06990 c9d1e76a08e2442a62d09ef64abfd222 378 Gene3D G3DSA:2.60.120.10 23 378 3.8E-109 T 12-10-2018 IPR014710 RmlC-like jelly roll fold VAPA_1c00130 0788813ddfacd41314167fa44c11717e 260 SUPERFAMILY SSF56219 13 258 3.14E-49 T 12-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily VAPA_1c00130 0788813ddfacd41314167fa44c11717e 260 Gene3D G3DSA:3.60.10.10 14 260 1.1E-41 T 12-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily VAPA_1c00130 0788813ddfacd41314167fa44c11717e 260 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 39 251 3.6E-17 T 12-10-2018 IPR005135 Endonuclease/exonuclease/phosphatase VAPA_1c13290 d5872a12a15ba2c2881cbab1a8594801 266 Gene3D G3DSA:1.10.3720.10 10 264 9.8E-41 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c13290 d5872a12a15ba2c2881cbab1a8594801 266 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 81 258 9.1E-13 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 VAPA_1c13290 d5872a12a15ba2c2881cbab1a8594801 266 SUPERFAMILY SSF161098 8 256 6.28E-42 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c03200 6de82840b735548e39684c3346921707 474 Gene3D G3DSA:1.20.1250.20 15 221 1.1E-7 T 12-10-2018 VAPA_1c03200 6de82840b735548e39684c3346921707 474 SUPERFAMILY SSF103473 47 465 1.92E-30 T 12-10-2018 IPR036259 MFS transporter superfamily VAPA_1c03200 6de82840b735548e39684c3346921707 474 Gene3D G3DSA:1.20.1250.20 274 472 1.2E-12 T 12-10-2018 VAPA_1c08080 82c70f74094d8247ef07084454f187df 318 SUPERFAMILY SSF103481 198 298 1.19E-11 T 12-10-2018 VAPA_1c08080 82c70f74094d8247ef07084454f187df 318 Pfam PF00892 EamA-like transporter family 12 147 1.6E-10 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 VAPA_1c08080 82c70f74094d8247ef07084454f187df 318 Pfam PF00892 EamA-like transporter family 164 295 4.6E-13 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 VAPA_1c08080 82c70f74094d8247ef07084454f187df 318 SUPERFAMILY SSF103481 53 148 9.81E-9 T 12-10-2018 VAPA_1c38250 a18ef73dfe4d18befc2bfafc46cfda0f 558 Gene3D G3DSA:1.10.3720.10 18 275 1.5E-50 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c38250 a18ef73dfe4d18befc2bfafc46cfda0f 558 SUPERFAMILY SSF161098 17 273 3.66E-42 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c38250 a18ef73dfe4d18befc2bfafc46cfda0f 558 SUPERFAMILY SSF161098 294 544 6.41E-33 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c38250 a18ef73dfe4d18befc2bfafc46cfda0f 558 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 87 267 1.5E-13 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 VAPA_1c38250 a18ef73dfe4d18befc2bfafc46cfda0f 558 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 379 540 8.1E-6 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 VAPA_1c38250 a18ef73dfe4d18befc2bfafc46cfda0f 558 Gene3D G3DSA:1.10.3720.10 293 549 2.6E-28 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c04340 4dcd0a61b1dce41f1d5b51f9e0d57a0d 247 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 239 5.7E-56 T 12-10-2018 VAPA_1c04340 4dcd0a61b1dce41f1d5b51f9e0d57a0d 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 171 188 5.1E-38 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c04340 4dcd0a61b1dce41f1d5b51f9e0d57a0d 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 125 141 5.1E-38 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c04340 4dcd0a61b1dce41f1d5b51f9e0d57a0d 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 5.1E-38 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c04340 4dcd0a61b1dce41f1d5b51f9e0d57a0d 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 5.1E-38 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c04340 4dcd0a61b1dce41f1d5b51f9e0d57a0d 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 150 169 5.1E-38 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c04340 4dcd0a61b1dce41f1d5b51f9e0d57a0d 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 204 224 5.1E-38 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c04340 4dcd0a61b1dce41f1d5b51f9e0d57a0d 247 Gene3D G3DSA:3.40.50.720 1 243 3.6E-71 T 12-10-2018 VAPA_1c04340 4dcd0a61b1dce41f1d5b51f9e0d57a0d 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 80 91 3.7E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c04340 4dcd0a61b1dce41f1d5b51f9e0d57a0d 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 150 169 3.7E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c04340 4dcd0a61b1dce41f1d5b51f9e0d57a0d 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 131 139 3.7E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c04340 4dcd0a61b1dce41f1d5b51f9e0d57a0d 247 SUPERFAMILY SSF51735 10 242 1.19E-71 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c04340 4dcd0a61b1dce41f1d5b51f9e0d57a0d 247 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 9 172 0.0021 T 12-10-2018 VAPA_1c06020 591481f2f3e24c68bc0ef9292cc63efc 266 Gene3D G3DSA:1.25.40.10 2 87 1.0E-18 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 VAPA_1c06020 591481f2f3e24c68bc0ef9292cc63efc 266 SUPERFAMILY SSF144059 4 263 3.01E-86 T 12-10-2018 VAPA_1c06020 591481f2f3e24c68bc0ef9292cc63efc 266 PIRSF PIRSF029288 1 266 1.2E-85 T 12-10-2018 IPR009211 Predicted virulence protein, SciE type VAPA_1c06020 591481f2f3e24c68bc0ef9292cc63efc 266 Pfam PF07024 ImpE protein 139 259 1.3E-43 T 12-10-2018 IPR009211 Predicted virulence protein, SciE type VAPA_1c06030 e6925698bef3ff4b506458d9829238ea 171 SUPERFAMILY SSF160719 73 150 7.98E-7 T 12-10-2018 VAPA_1c06030 e6925698bef3ff4b506458d9829238ea 171 Pfam PF04965 Gene 25-like lysozyme 39 143 5.2E-20 T 12-10-2018 IPR007048 GpW/Gp25/anti-adapter protein IraD VAPA_1c06030 e6925698bef3ff4b506458d9829238ea 171 TIGRFAM TIGR03357 VI_zyme: type VI secretion system lysozyme-like protein 11 162 4.7E-19 T 12-10-2018 IPR017737 Type VI secretion system, lysozyme-related protein VAPA_1c21360 fb724c9b4098eedb186d69011753c831 167 Gene3D G3DSA:2.70.70.10 37 162 3.2E-33 T 12-10-2018 IPR011055 Duplicated hybrid motif VAPA_1c21360 fb724c9b4098eedb186d69011753c831 167 SUPERFAMILY SSF51261 40 161 5.75E-41 T 12-10-2018 IPR011055 Duplicated hybrid motif VAPA_1c21360 fb724c9b4098eedb186d69011753c831 167 Pfam PF01551 Peptidase family M23 64 157 2.6E-28 T 12-10-2018 IPR016047 Peptidase M23 VAPA_1c26460 48b75cdfd13106be914ea9b8d352b08d 256 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 98 256 1.9E-10 T 12-10-2018 IPR011234 Fumarylacetoacetase-like, C-terminal GO:0003824 VAPA_1c26460 48b75cdfd13106be914ea9b8d352b08d 256 Gene3D G3DSA:3.90.850.10 2 256 9.9E-54 T 12-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 VAPA_1c26460 48b75cdfd13106be914ea9b8d352b08d 256 SUPERFAMILY SSF56529 5 256 6.15E-36 T 12-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 VAPA_1c09650 b9685995db11cc0964dc4f8d4d6c4544 115 Pfam PF04999 Cell division protein FtsL 3 85 1.4E-19 T 12-10-2018 IPR011922 Cell division protein FtsL GO:0016021|GO:0051301 VAPA_1c09650 b9685995db11cc0964dc4f8d4d6c4544 115 Hamap MF_00910 Cell division protein FtsL [ftsL]. 1 84 15.523 T 12-10-2018 IPR011922 Cell division protein FtsL GO:0016021|GO:0051301 VAPA_1c09650 b9685995db11cc0964dc4f8d4d6c4544 115 TIGRFAM TIGR02209 ftsL_broad: cell division protein FtsL 3 84 2.3E-19 T 12-10-2018 IPR011922 Cell division protein FtsL GO:0016021|GO:0051301 VAPA_1c03490 fde3df8325b43440855d75ab53cb4e05 655 Hamap MF_02081 Peptidoglycan D,D-transpeptidase MrdA [mrdA]. 3 616 48.272 T 12-10-2018 IPR017790 Penicillin-binding protein 2 GO:0008658|GO:0009002|GO:0009252|GO:0016020 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 VAPA_1c03490 fde3df8325b43440855d75ab53cb4e05 655 Pfam PF00905 Penicillin binding protein transpeptidase domain 270 608 1.9E-69 T 12-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 VAPA_1c03490 fde3df8325b43440855d75ab53cb4e05 655 Gene3D G3DSA:3.40.710.10 252 617 2.2E-97 T 12-10-2018 VAPA_1c03490 fde3df8325b43440855d75ab53cb4e05 655 SUPERFAMILY SSF56601 253 612 1.22E-96 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like VAPA_1c03490 fde3df8325b43440855d75ab53cb4e05 655 Pfam PF03717 Penicillin-binding Protein dimerisation domain 62 237 2.0E-43 T 12-10-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 VAPA_1c03490 fde3df8325b43440855d75ab53cb4e05 655 Gene3D G3DSA:3.30.1390.30 82 157 8.8E-45 T 12-10-2018 VAPA_1c03490 fde3df8325b43440855d75ab53cb4e05 655 SUPERFAMILY SSF56519 54 252 1.12E-47 T 12-10-2018 IPR036138 Penicillin-binding protein, dimerisation domain superfamily GO:0008658 VAPA_1c03490 fde3df8325b43440855d75ab53cb4e05 655 Gene3D G3DSA:3.90.1310.10 62 247 8.8E-45 T 12-10-2018 VAPA_1c03490 fde3df8325b43440855d75ab53cb4e05 655 TIGRFAM TIGR03423 pbp2_mrdA: penicillin-binding protein 2 16 613 5.0E-226 T 12-10-2018 IPR017790 Penicillin-binding protein 2 GO:0008658|GO:0009002|GO:0009252|GO:0016020 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 VAPA_2c11660 23e0ac1f584ddea453273a8cf7643aae 282 Pfam PF03403 Platelet-activating factor acetylhydrolase, isoform II 35 90 3.6E-8 T 12-10-2018 IPR005065 Platelet-activating factor acetylhydrolase-like GO:0003847|GO:0016042 KEGG: 00565+3.1.1.47 VAPA_2c11660 23e0ac1f584ddea453273a8cf7643aae 282 Gene3D G3DSA:3.40.50.1820 10 253 2.3E-42 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_2c11660 23e0ac1f584ddea453273a8cf7643aae 282 PIRSF PIRSF031982 1 162 1.2E-44 T 12-10-2018 IPR016986 Uncharacterised conserved protein UCP031982, alpha/beta hydrolase, XabL VAPA_2c11660 23e0ac1f584ddea453273a8cf7643aae 282 PIRSF PIRSF031982 157 281 8.9E-23 T 12-10-2018 IPR016986 Uncharacterised conserved protein UCP031982, alpha/beta hydrolase, XabL VAPA_2c11660 23e0ac1f584ddea453273a8cf7643aae 282 SUPERFAMILY SSF53474 40 244 1.66E-36 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c22270 5cdf7bc9b3ca0d6ba884ac235bf4e231 296 Pfam PF00753 Metallo-beta-lactamase superfamily 17 214 3.5E-21 T 12-10-2018 IPR001279 Metallo-beta-lactamase VAPA_1c22270 5cdf7bc9b3ca0d6ba884ac235bf4e231 296 Gene3D G3DSA:3.60.15.10 5 296 1.9E-103 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like VAPA_1c22270 5cdf7bc9b3ca0d6ba884ac235bf4e231 296 SUPERFAMILY SSF56281 17 294 4.46E-48 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like VAPA_1c22270 5cdf7bc9b3ca0d6ba884ac235bf4e231 296 SMART SM00849 20 214 1.0E-24 T 12-10-2018 IPR001279 Metallo-beta-lactamase VAPA_1c08180 5ef2fe85e50a9785432c51f13671f042 971 Pfam PF13692 Glycosyl transferases group 1 804 937 3.2E-15 T 12-10-2018 VAPA_1c08180 5ef2fe85e50a9785432c51f13671f042 971 Gene3D G3DSA:3.40.50.2000 791 954 8.4E-9 T 12-10-2018 VAPA_1c08180 5ef2fe85e50a9785432c51f13671f042 971 SUPERFAMILY SSF53756 568 970 3.1E-19 T 12-10-2018 VAPA_1c08180 5ef2fe85e50a9785432c51f13671f042 971 Gene3D G3DSA:3.90.550.10 15 169 9.7E-15 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases VAPA_1c08180 5ef2fe85e50a9785432c51f13671f042 971 SUPERFAMILY SSF53448 24 158 7.69E-17 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases VAPA_1c08180 5ef2fe85e50a9785432c51f13671f042 971 Pfam PF00535 Glycosyl transferase family 2 27 146 1.2E-11 T 12-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 VAPA_1c04330 eebafc7bc61bddb2269dfafb647fa5df 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 1.1E-43 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c04330 eebafc7bc61bddb2269dfafb647fa5df 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 210 230 1.1E-43 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c04330 eebafc7bc61bddb2269dfafb647fa5df 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 1.1E-43 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c04330 eebafc7bc61bddb2269dfafb647fa5df 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 1.1E-43 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c04330 eebafc7bc61bddb2269dfafb647fa5df 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 1.1E-43 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c04330 eebafc7bc61bddb2269dfafb647fa5df 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 1.1E-43 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c04330 eebafc7bc61bddb2269dfafb647fa5df 249 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 141 169 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 VAPA_1c04330 eebafc7bc61bddb2269dfafb647fa5df 249 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 6 185 7.6E-4 T 12-10-2018 VAPA_1c04330 eebafc7bc61bddb2269dfafb647fa5df 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 1.9E-12 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c04330 eebafc7bc61bddb2269dfafb647fa5df 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 1.9E-12 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c04330 eebafc7bc61bddb2269dfafb647fa5df 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 1.9E-12 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c04330 eebafc7bc61bddb2269dfafb647fa5df 249 SUPERFAMILY SSF51735 4 248 2.5E-80 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c04330 eebafc7bc61bddb2269dfafb647fa5df 249 Gene3D G3DSA:3.40.50.720 2 249 1.2E-81 T 12-10-2018 VAPA_1c04330 eebafc7bc61bddb2269dfafb647fa5df 249 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 246 5.3E-65 T 12-10-2018 VAPA_1c08280 2227c731f6ab87692e9ac7efc48910aa 472 Pfam PF00483 Nucleotidyl transferase 5 284 5.3E-51 T 12-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 VAPA_1c08280 2227c731f6ab87692e9ac7efc48910aa 472 Gene3D G3DSA:2.60.120.10 368 462 1.1E-17 T 12-10-2018 IPR014710 RmlC-like jelly roll fold VAPA_1c08280 2227c731f6ab87692e9ac7efc48910aa 472 SUPERFAMILY SSF51182 184 471 1.11E-69 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily VAPA_1c08280 2227c731f6ab87692e9ac7efc48910aa 472 SUPERFAMILY SSF53448 2 280 4.96E-65 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases VAPA_1c08280 2227c731f6ab87692e9ac7efc48910aa 472 Pfam PF01050 Mannose-6-phosphate isomerase 317 467 2.0E-54 T 12-10-2018 IPR001538 Mannose-6-phosphate isomerase, type II, C-terminal GO:0005976|GO:0016779 KEGG: 00051+2.7.7.13|KEGG: 00520+2.7.7.13|MetaCyc: PWY-5659|MetaCyc: PWY-882 VAPA_1c08280 2227c731f6ab87692e9ac7efc48910aa 472 TIGRFAM TIGR01479 GMP_PMI: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase 4 471 5.2E-157 T 12-10-2018 IPR006375 Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase GO:0000271|GO:0016779 KEGG: 00051+2.7.7.13|KEGG: 00520+2.7.7.13|MetaCyc: PWY-5659|MetaCyc: PWY-882 VAPA_1c08280 2227c731f6ab87692e9ac7efc48910aa 472 Gene3D G3DSA:3.90.550.10 1 353 6.4E-109 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases VAPA_1c40730 6f3dbf1a78088205e495b108537e5d21 497 Pfam PF02133 Permease for cytosine/purines, uracil, thiamine, allantoin 44 480 2.7E-93 T 12-10-2018 IPR001248 Purine-cytosine permease GO:0016020|GO:0022857|GO:0055085 VAPA_1c40730 6f3dbf1a78088205e495b108537e5d21 497 Gene3D G3DSA:1.10.4160.10 29 495 1.0E-111 T 12-10-2018 IPR038271 Purine-cytosine permease superfamily VAPA_1c08580 281bbca303d434f9caf8c730b3abca63 318 Gene3D G3DSA:3.40.190.10 121 243 9.2E-106 T 12-10-2018 VAPA_1c08580 281bbca303d434f9caf8c730b3abca63 318 PIRSF PIRSF017082 3 317 2.2E-72 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c08580 281bbca303d434f9caf8c730b3abca63 318 Gene3D G3DSA:3.40.190.150 26 308 9.2E-106 T 12-10-2018 VAPA_1c08580 281bbca303d434f9caf8c730b3abca63 318 SUPERFAMILY SSF53850 97 266 1.14E-7 T 12-10-2018 VAPA_1c08580 281bbca303d434f9caf8c730b3abca63 318 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 44 311 8.2E-84 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c41210 7da0a535f1f0b9eb8a6bda7deb1fa9b6 290 Gene3D G3DSA:1.10.1040.10 164 289 1.7E-26 T 12-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 VAPA_1c41210 7da0a535f1f0b9eb8a6bda7deb1fa9b6 290 PIRSF PIRSF000103 1 290 2.2E-71 T 12-10-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 VAPA_1c41210 7da0a535f1f0b9eb8a6bda7deb1fa9b6 290 SUPERFAMILY SSF51735 1 166 5.02E-36 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c41210 7da0a535f1f0b9eb8a6bda7deb1fa9b6 290 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 2 162 5.7E-37 T 12-10-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 VAPA_1c41210 7da0a535f1f0b9eb8a6bda7deb1fa9b6 290 Gene3D G3DSA:3.40.50.720 1 163 2.9E-44 T 12-10-2018 VAPA_1c41210 7da0a535f1f0b9eb8a6bda7deb1fa9b6 290 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 170 286 2.7E-19 T 12-10-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 VAPA_1c41210 7da0a535f1f0b9eb8a6bda7deb1fa9b6 290 SUPERFAMILY SSF48179 166 287 3.85E-25 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 VAPA_1c19360 ce4d0aa0808ae342000d42ffc46dfbda 189 Gene3D G3DSA:2.40.50.870 36 188 7.3E-46 T 12-10-2018 VAPA_1c19360 ce4d0aa0808ae342000d42ffc46dfbda 189 Pfam PF11736 Protein of unknown function (DUF3299) 43 184 8.2E-39 T 12-10-2018 IPR021727 Protein of unknown function DUF3299 VAPA_1c20130 0b239fb09d975d11ca1edcb315d5b0ff 317 Pfam PF08843 Nucleotidyl transferase AbiEii toxin, Type IV TA system 35 262 6.0E-40 T 12-10-2018 IPR014942 Nucleotidyl transferase AbiEii toxin, Type IV TA system VAPA_1c22370 6e9a274f668703beead137d9c0a333bd 420 SUPERFAMILY SSF54427 237 380 5.36E-23 T 12-10-2018 IPR032710 NTF2-like domain superfamily VAPA_1c22370 6e9a274f668703beead137d9c0a333bd 420 Gene3D G3DSA:3.40.50.1820 1 231 1.7E-59 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c22370 6e9a274f668703beead137d9c0a333bd 420 SUPERFAMILY SSF53474 3 229 6.04E-50 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c22370 6e9a274f668703beead137d9c0a333bd 420 Pfam PF01738 Dienelactone hydrolase family 16 230 3.0E-51 T 12-10-2018 IPR002925 Dienelactone hydrolase GO:0016787 VAPA_1c22370 6e9a274f668703beead137d9c0a333bd 420 Gene3D G3DSA:3.10.450.50 240 375 1.2E-21 T 12-10-2018 VAPA_1c05860 4e40ec2cffd6137f44a3dfa654c35937 265 SUPERFAMILY SSF53448 57 243 2.93E-7 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases VAPA_1c05860 4e40ec2cffd6137f44a3dfa654c35937 265 Gene3D G3DSA:3.90.550.10 48 246 4.2E-5 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases VAPA_1c55120 af1288a14ad7f09c291e59d6b6aa1963 139 Pfam PF00825 Ribonuclease P 2 103 1.1E-11 T 12-10-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 VAPA_1c55120 af1288a14ad7f09c291e59d6b6aa1963 139 Gene3D G3DSA:3.30.230.10 1 125 5.2E-11 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup VAPA_1c55120 af1288a14ad7f09c291e59d6b6aa1963 139 SUPERFAMILY SSF54211 2 101 1.42E-10 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold VAPA_1c35110 9e683a56e4968bb83b578f6c57e36d68 304 Pfam PF03466 LysR substrate binding domain 87 293 1.9E-34 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_1c35110 9e683a56e4968bb83b578f6c57e36d68 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 5.9E-5 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c35110 9e683a56e4968bb83b578f6c57e36d68 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 5.9E-5 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c35110 9e683a56e4968bb83b578f6c57e36d68 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 5.9E-5 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c35110 9e683a56e4968bb83b578f6c57e36d68 304 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 62 2.1E-16 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c35110 9e683a56e4968bb83b578f6c57e36d68 304 SUPERFAMILY SSF46785 3 110 4.63E-20 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c35110 9e683a56e4968bb83b578f6c57e36d68 304 Gene3D G3DSA:3.40.190.10 91 279 8.0E-28 T 12-10-2018 VAPA_1c35110 9e683a56e4968bb83b578f6c57e36d68 304 Gene3D G3DSA:3.40.190.10 164 268 8.0E-28 T 12-10-2018 VAPA_1c35110 9e683a56e4968bb83b578f6c57e36d68 304 SUPERFAMILY SSF53850 88 297 9.32E-36 T 12-10-2018 VAPA_1c35110 9e683a56e4968bb83b578f6c57e36d68 304 Gene3D G3DSA:1.10.10.10 1 89 3.7E-24 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_2c04020 3f48512fd85092cce84e86b36ec6fa15 142 SUPERFAMILY SSF52402 1 142 8.37E-31 T 12-10-2018 VAPA_2c04020 3f48512fd85092cce84e86b36ec6fa15 142 Pfam PF00582 Universal stress protein family 2 142 4.3E-27 T 12-10-2018 IPR006016 UspA VAPA_2c04020 3f48512fd85092cce84e86b36ec6fa15 142 Gene3D G3DSA:3.40.50.620 1 142 7.5E-32 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold VAPA_2c04020 3f48512fd85092cce84e86b36ec6fa15 142 PRINTS PR01438 Universal stress protein signature 102 114 3.3E-10 T 12-10-2018 IPR006015 Universal stress protein A VAPA_2c04020 3f48512fd85092cce84e86b36ec6fa15 142 PRINTS PR01438 Universal stress protein signature 120 142 3.3E-10 T 12-10-2018 IPR006015 Universal stress protein A VAPA_1c17890 ad679b4a9f9b969b8301f249a7d08dc2 291 Gene3D G3DSA:3.40.50.1820 5 290 3.6E-82 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c17890 ad679b4a9f9b969b8301f249a7d08dc2 291 SUPERFAMILY SSF53474 5 289 8.88E-79 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c17890 ad679b4a9f9b969b8301f249a7d08dc2 291 TIGRFAM TIGR02821 fghA_ester_D: S-formylglutathione hydrolase 7 289 6.1E-123 T 12-10-2018 IPR014186 S-formylglutathione hydrolase GO:0018738|GO:0046294 KEGG: 00680+3.1.2.12|MetaCyc: PWY-1801|Reactome: R-HSA-156590 VAPA_1c17890 ad679b4a9f9b969b8301f249a7d08dc2 291 Pfam PF00756 Putative esterase 25 283 1.3E-54 T 12-10-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 VAPA_2c02950 1ffee843697a9fb0023765502ff8e11f 315 SUPERFAMILY SSF46785 1 110 4.84E-16 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_2c02950 1ffee843697a9fb0023765502ff8e11f 315 Gene3D G3DSA:3.40.190.290 92 293 5.9E-33 T 12-10-2018 VAPA_2c02950 1ffee843697a9fb0023765502ff8e11f 315 Gene3D G3DSA:1.10.10.10 1 91 2.8E-14 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_2c02950 1ffee843697a9fb0023765502ff8e11f 315 SUPERFAMILY SSF53850 88 293 3.55E-37 T 12-10-2018 VAPA_2c02950 1ffee843697a9fb0023765502ff8e11f 315 Pfam PF03466 LysR substrate binding domain 87 287 1.9E-35 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_2c02950 1ffee843697a9fb0023765502ff8e11f 315 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 1.1E-13 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_2c12360 f41406ef00babe865a6bdff8fe4e810c 518 Gene3D G3DSA:3.40.920.10 10 216 8.0E-11 T 12-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 VAPA_2c12360 f41406ef00babe865a6bdff8fe4e810c 518 SUPERFAMILY SSF53323 13 214 3.92E-11 T 12-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 VAPA_2c12360 f41406ef00babe865a6bdff8fe4e810c 518 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 20 211 8.5E-17 T 12-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 VAPA_1c15900 510451b98d280659f7a533e61ea44f3b 270 Pfam PF04199 Putative cyclase 29 205 1.0E-34 T 12-10-2018 IPR007325 Kynurenine formamidase/cyclase-like GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 VAPA_1c15900 510451b98d280659f7a533e61ea44f3b 270 Gene3D G3DSA:3.50.30.50 8 268 1.6E-89 T 12-10-2018 IPR037175 Kynurenine formamidase superfamily GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 VAPA_1c15900 510451b98d280659f7a533e61ea44f3b 270 SUPERFAMILY SSF102198 26 266 1.31E-54 T 12-10-2018 IPR037175 Kynurenine formamidase superfamily GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 VAPA_1c14070 b73d3a286f40b9b791531b6615f4b09e 294 Gene3D G3DSA:3.40.190.10 161 261 1.2E-41 T 12-10-2018 VAPA_1c14070 b73d3a286f40b9b791531b6615f4b09e 294 Pfam PF03466 LysR substrate binding domain 91 292 6.4E-26 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_1c14070 b73d3a286f40b9b791531b6615f4b09e 294 Gene3D G3DSA:3.40.190.10 101 288 1.2E-41 T 12-10-2018 VAPA_1c14070 b73d3a286f40b9b791531b6615f4b09e 294 SUPERFAMILY SSF46785 8 112 8.17E-15 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c14070 b73d3a286f40b9b791531b6615f4b09e 294 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 12 55 2.6E-13 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c14070 b73d3a286f40b9b791531b6615f4b09e 294 Gene3D G3DSA:1.10.10.10 8 96 1.7E-14 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c14070 b73d3a286f40b9b791531b6615f4b09e 294 SUPERFAMILY SSF53850 92 293 8.87E-31 T 12-10-2018 VAPA_1c48690 224ac544ed7ce6f1e28f3323a60deca8 127 Pfam PF07883 Cupin domain 46 113 7.1E-20 T 12-10-2018 IPR013096 Cupin 2, conserved barrel VAPA_1c48690 224ac544ed7ce6f1e28f3323a60deca8 127 Gene3D G3DSA:2.60.120.10 3 121 4.6E-24 T 12-10-2018 IPR014710 RmlC-like jelly roll fold VAPA_1c48690 224ac544ed7ce6f1e28f3323a60deca8 127 SUPERFAMILY SSF51182 5 118 1.29E-29 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily VAPA_1c47180 effdc44278466e880f20d9eb08786111 368 Pfam PF03432 Relaxase/Mobilisation nuclease domain 129 227 1.4E-9 T 12-10-2018 IPR005094 Endonuclease relaxase, MobA/VirD2 VAPA_1c49440 80869f21873e8759c16cfd2d5a0cecba 403 Gene3D G3DSA:3.90.930.1 60 179 3.8E-12 T 12-10-2018 VAPA_1c49440 80869f21873e8759c16cfd2d5a0cecba 403 SUPERFAMILY SSF82185 74 152 3.01E-8 T 12-10-2018 VAPA_1c49440 80869f21873e8759c16cfd2d5a0cecba 403 Gene3D G3DSA:3.90.930.1 273 403 9.8E-8 T 12-10-2018 VAPA_1c49440 80869f21873e8759c16cfd2d5a0cecba 403 Pfam PF07661 MORN repeat variant 112 132 0.25 T 12-10-2018 IPR011652 MORN variant VAPA_1c49440 80869f21873e8759c16cfd2d5a0cecba 403 Pfam PF07661 MORN repeat variant 136 154 0.051 T 12-10-2018 IPR011652 MORN variant VAPA_1c32880 97d6e115d455757b7d1dab13e954a10e 392 Gene3D G3DSA:3.10.560.10 69 361 3.5E-92 T 12-10-2018 VAPA_1c32880 97d6e115d455757b7d1dab13e954a10e 392 Pfam PF02563 Polysaccharide biosynthesis/export protein 96 188 1.7E-21 T 12-10-2018 IPR003715 Polysaccharide export protein GO:0015159|GO:0015774|GO:0016020 VAPA_1c32880 97d6e115d455757b7d1dab13e954a10e 392 Pfam PF10531 SLBB domain 195 243 2.5E-9 T 12-10-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VAPA_1c32880 97d6e115d455757b7d1dab13e954a10e 392 Pfam PF10531 SLBB domain 280 326 7.9E-4 T 12-10-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VAPA_1c32880 97d6e115d455757b7d1dab13e954a10e 392 Gene3D G3DSA:3.30.1950.10 103 192 3.5E-92 T 12-10-2018 VAPA_1c32880 97d6e115d455757b7d1dab13e954a10e 392 Gene3D G3DSA:3.10.560.10 81 277 3.5E-92 T 12-10-2018 VAPA_1c09850 03d87c359458100b56fc11e78c70a85d 148 Pfam PF10990 Protein of unknown function (DUF2809) 38 118 3.8E-21 T 12-10-2018 IPR021257 Protein of unknown function DUF2809 VAPA_2c10700 4c8abac440f8f0183ee5d6cd4b7b8a78 245 SMART SM00346 1 90 3.2E-4 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 VAPA_2c10700 4c8abac440f8f0183ee5d6cd4b7b8a78 245 Pfam PF01614 Bacterial transcriptional regulator 124 240 1.7E-12 T 12-10-2018 IPR014757 Transcription regulator IclR, C-terminal VAPA_2c10700 4c8abac440f8f0183ee5d6cd4b7b8a78 245 Gene3D G3DSA:1.10.10.10 1 72 1.8E-11 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_2c10700 4c8abac440f8f0183ee5d6cd4b7b8a78 245 SUPERFAMILY SSF55781 58 244 2.24E-28 T 12-10-2018 VAPA_2c10700 4c8abac440f8f0183ee5d6cd4b7b8a78 245 SUPERFAMILY SSF46785 1 72 5.55E-12 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_2c10700 4c8abac440f8f0183ee5d6cd4b7b8a78 245 Gene3D G3DSA:3.30.450.40 73 238 9.2E-27 T 12-10-2018 IPR029016 GAF-like domain superfamily VAPA_1c31110 a763ef512b7fe41e069f4a9d50d301ed 312 SUPERFAMILY SSF51004 9 298 7.06E-65 T 12-10-2018 IPR011048 Cytochrome cd1-nitrite reductase-like, haem d1 domain superfamily VAPA_1c31110 a763ef512b7fe41e069f4a9d50d301ed 312 Pfam PF02239 Cytochrome D1 heme domain 15 114 2.1E-6 T 12-10-2018 VAPA_1c31110 a763ef512b7fe41e069f4a9d50d301ed 312 Gene3D G3DSA:2.130.10.10 10 201 2.4E-54 T 12-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 VAPA_1c31110 a763ef512b7fe41e069f4a9d50d301ed 312 Gene3D G3DSA:2.130.10.10 202 305 9.7E-25 T 12-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 VAPA_1c31110 a763ef512b7fe41e069f4a9d50d301ed 312 TIGRFAM TIGR02276 beta_rpt_yvtn: 40-residue YVTN family beta-propeller repeat 226 263 5.5E-11 T 12-10-2018 IPR011964 YVTN beta-propeller repeat VAPA_1c31110 a763ef512b7fe41e069f4a9d50d301ed 312 TIGRFAM TIGR02276 beta_rpt_yvtn: 40-residue YVTN family beta-propeller repeat 137 178 1.4E-12 T 12-10-2018 IPR011964 YVTN beta-propeller repeat VAPA_1c31110 a763ef512b7fe41e069f4a9d50d301ed 312 TIGRFAM TIGR02276 beta_rpt_yvtn: 40-residue YVTN family beta-propeller repeat 14 48 4.9E-12 T 12-10-2018 IPR011964 YVTN beta-propeller repeat VAPA_1c31110 a763ef512b7fe41e069f4a9d50d301ed 312 TIGRFAM TIGR02276 beta_rpt_yvtn: 40-residue YVTN family beta-propeller repeat 183 221 2.4E-7 T 12-10-2018 IPR011964 YVTN beta-propeller repeat VAPA_1c35020 5cd104f1cc10c482408b5c9d37c94c14 912 SUPERFAMILY SSF56059 130 523 1.2E-18 T 12-10-2018 VAPA_1c35020 5cd104f1cc10c482408b5c9d37c94c14 912 Pfam PF04168 A predicted alpha-helical domain with a conserved ER motif. 586 900 4.9E-62 T 12-10-2018 IPR007296 Domain of unknown function DUF403 VAPA_1c35020 5cd104f1cc10c482408b5c9d37c94c14 912 Gene3D G3DSA:3.40.50.11290 291 387 1.8E-40 T 12-10-2018 VAPA_1c35020 5cd104f1cc10c482408b5c9d37c94c14 912 Pfam PF14403 Circularly permuted ATP-grasp type 2 153 537 9.6E-148 T 12-10-2018 IPR025841 Circularly permuted ATP-grasp type 2 VAPA_1c12010 399b8606b2b4c9e5bfed7427ba149a48 227 Pfam PF04350 Pilus assembly protein, PilO 66 210 2.7E-52 T 12-10-2018 IPR007445 Pilus assembly protein, PilO VAPA_1c12010 399b8606b2b4c9e5bfed7427ba149a48 227 PIRSF PIRSF016482 14 227 7.2E-54 T 12-10-2018 IPR007445 Pilus assembly protein, PilO VAPA_1c12010 399b8606b2b4c9e5bfed7427ba149a48 227 Gene3D G3DSA:3.30.70.60 111 219 9.6E-36 T 12-10-2018 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 VAPA_1c46220 c0e72085377cbe48a7a1dc01289c4b13 438 SUPERFAMILY SSF52540 67 371 1.39E-58 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c46220 c0e72085377cbe48a7a1dc01289c4b13 438 Gene3D G3DSA:3.40.50.300 185 426 5.2E-71 T 12-10-2018 VAPA_1c46220 c0e72085377cbe48a7a1dc01289c4b13 438 Gene3D G3DSA:3.30.450.380 16 184 9.2E-40 T 12-10-2018 VAPA_1c46220 c0e72085377cbe48a7a1dc01289c4b13 438 Pfam PF00437 Type II/IV secretion system protein 90 365 2.9E-77 T 12-10-2018 IPR001482 Type II/IV secretion system protein VAPA_1c42030 e8db3dd152c0b66831b954dee71b81c8 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 1.0E-40 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c42030 e8db3dd152c0b66831b954dee71b81c8 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 1.0E-40 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c42030 e8db3dd152c0b66831b954dee71b81c8 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 1.0E-40 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c42030 e8db3dd152c0b66831b954dee71b81c8 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 1.0E-40 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c42030 e8db3dd152c0b66831b954dee71b81c8 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 1.0E-40 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c42030 e8db3dd152c0b66831b954dee71b81c8 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 210 230 1.0E-40 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c42030 e8db3dd152c0b66831b954dee71b81c8 247 SUPERFAMILY SSF51735 8 246 1.7E-79 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c42030 e8db3dd152c0b66831b954dee71b81c8 247 Gene3D G3DSA:3.40.50.720 1 246 2.8E-79 T 12-10-2018 VAPA_1c42030 e8db3dd152c0b66831b954dee71b81c8 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 1.3E-11 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c42030 e8db3dd152c0b66831b954dee71b81c8 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 1.3E-11 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c42030 e8db3dd152c0b66831b954dee71b81c8 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 1.3E-11 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c42030 e8db3dd152c0b66831b954dee71b81c8 247 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 8 191 1.9E-5 T 12-10-2018 VAPA_1c42030 e8db3dd152c0b66831b954dee71b81c8 247 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 246 1.2E-62 T 12-10-2018 VAPA_1c42030 e8db3dd152c0b66831b954dee71b81c8 247 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 142 170 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 VAPA_1c07060 2aac9cf1ca263d1c81002c5128319580 182 SUPERFAMILY SSF50475 15 170 6.54E-42 T 12-10-2018 VAPA_1c07060 2aac9cf1ca263d1c81002c5128319580 182 SMART SM00903 21 168 1.2E-44 T 12-10-2018 IPR002563 Flavin reductase like domain GO:0010181 VAPA_1c07060 2aac9cf1ca263d1c81002c5128319580 182 Gene3D G3DSA:2.30.110.10 4 177 1.6E-46 T 12-10-2018 IPR012349 FMN-binding split barrel GO:0048037 VAPA_1c07060 2aac9cf1ca263d1c81002c5128319580 182 Pfam PF01613 Flavin reductase like domain 21 165 3.2E-36 T 12-10-2018 IPR002563 Flavin reductase like domain GO:0010181 VAPA_1c46110 a3eb9f416a65da17dfc90ae2adb5257a 233 Pfam PF01144 Coenzyme A transferase 8 217 7.6E-69 T 12-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 VAPA_1c46110 a3eb9f416a65da17dfc90ae2adb5257a 233 SMART SM00882 6 219 5.8E-80 T 12-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 VAPA_1c46110 a3eb9f416a65da17dfc90ae2adb5257a 233 Gene3D G3DSA:3.40.1080.10 1 218 1.3E-79 T 12-10-2018 VAPA_1c46110 a3eb9f416a65da17dfc90ae2adb5257a 233 TIGRFAM TIGR02429 pcaI_scoA_fam: 3-oxoacid CoA-transferase, A subunit 1 220 2.5E-113 T 12-10-2018 IPR012792 3-oxoacid CoA-transferase, subunit A GO:0008410 Reactome: R-HSA-77108 VAPA_1c46110 a3eb9f416a65da17dfc90ae2adb5257a 233 SUPERFAMILY SSF100950 2 222 6.8E-76 T 12-10-2018 IPR037171 NagB/RpiA transferase-like VAPA_1c46110 a3eb9f416a65da17dfc90ae2adb5257a 233 ProSitePatterns PS01273 Coenzyme A transferases signature 1. 18 33 - T 12-10-2018 IPR004163 Coenzyme A transferase binding site GO:0008410 Reactome: R-HSA-77108 VAPA_1c06380 386571c9534636ad46de854bbff2f246 160 TIGRFAM TIGR04044 MSMEG_0572_fam: MSMEG_0572 family protein 2 160 6.3E-86 T 12-10-2018 IPR023847 Conserved hypothetical protein CHP04044, MSMEG0572 VAPA_1c06380 386571c9534636ad46de854bbff2f246 160 Pfam PF02635 DsrE/DsrF-like family 48 143 6.2E-5 T 12-10-2018 IPR003787 Sulphur relay, DsrE/F-like protein VAPA_1c06380 386571c9534636ad46de854bbff2f246 160 SUPERFAMILY SSF75169 33 145 1.26E-11 T 12-10-2018 IPR027396 DsrEFH-like VAPA_1c06380 386571c9534636ad46de854bbff2f246 160 Gene3D G3DSA:3.40.1260.10 32 150 8.4E-8 T 12-10-2018 IPR027396 DsrEFH-like VAPA_2c10420 f874feef9c8192b207c7b912f2295d2a 238 SMART SM00382 29 201 5.2E-7 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_2c10420 f874feef9c8192b207c7b912f2295d2a 238 Pfam PF00005 ABC transporter 22 160 5.0E-27 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_2c10420 f874feef9c8192b207c7b912f2295d2a 238 SUPERFAMILY SSF52540 4 223 1.43E-53 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_2c10420 f874feef9c8192b207c7b912f2295d2a 238 Gene3D G3DSA:3.40.50.300 2 234 3.3E-53 T 12-10-2018 VAPA_2c10420 f874feef9c8192b207c7b912f2295d2a 238 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_1c53450 49f411675ee078132f81cb9848dea5b3 187 SUPERFAMILY SSF103088 70 183 4.45E-34 T 12-10-2018 IPR036737 OmpA-like domain superfamily VAPA_1c53450 49f411675ee078132f81cb9848dea5b3 187 PRINTS PR01021 OMPA domain signature 83 105 8.6E-13 T 12-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 VAPA_1c53450 49f411675ee078132f81cb9848dea5b3 187 PRINTS PR01021 OMPA domain signature 113 128 8.6E-13 T 12-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 VAPA_1c53450 49f411675ee078132f81cb9848dea5b3 187 PRINTS PR01021 OMPA domain signature 128 144 8.6E-13 T 12-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 VAPA_1c53450 49f411675ee078132f81cb9848dea5b3 187 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 128 145 7.9E-8 T 12-10-2018 VAPA_1c53450 49f411675ee078132f81cb9848dea5b3 187 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 166 186 7.9E-8 T 12-10-2018 VAPA_1c53450 49f411675ee078132f81cb9848dea5b3 187 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 146 165 7.9E-8 T 12-10-2018 VAPA_1c53450 49f411675ee078132f81cb9848dea5b3 187 Pfam PF00691 OmpA family 83 177 1.4E-20 T 12-10-2018 IPR006665 OmpA-like domain VAPA_1c53450 49f411675ee078132f81cb9848dea5b3 187 Gene3D G3DSA:3.30.1330.60 47 187 3.5E-39 T 12-10-2018 IPR036737 OmpA-like domain superfamily VAPA_1c28510 839be1722ce368dc9fac8a17c02915d0 280 Pfam PF00899 ThiF family 38 187 8.0E-35 T 12-10-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 VAPA_1c28510 839be1722ce368dc9fac8a17c02915d0 280 SUPERFAMILY SSF69572 28 276 1.24E-52 T 12-10-2018 IPR035985 Ubiquitin-activating enzyme GO:0008641 VAPA_1c28510 839be1722ce368dc9fac8a17c02915d0 280 Gene3D G3DSA:3.40.50.720 20 280 6.2E-84 T 12-10-2018 VAPA_1c45170 457bbd737c563395a604547f50b722d9 210 TIGRFAM TIGR00447 pth: aminoacyl-tRNA hydrolase 2 183 1.4E-59 T 12-10-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 VAPA_1c45170 457bbd737c563395a604547f50b722d9 210 Gene3D G3DSA:3.40.50.1470 1 191 3.0E-67 T 12-10-2018 IPR036416 Peptidyl-tRNA hydrolase superfamily GO:0004045 MetaCyc: PWY-6308 VAPA_1c45170 457bbd737c563395a604547f50b722d9 210 SUPERFAMILY SSF53178 1 188 4.32E-67 T 12-10-2018 IPR036416 Peptidyl-tRNA hydrolase superfamily GO:0004045 MetaCyc: PWY-6308 VAPA_1c45170 457bbd737c563395a604547f50b722d9 210 Pfam PF01195 Peptidyl-tRNA hydrolase 4 182 1.3E-54 T 12-10-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 VAPA_1c45170 457bbd737c563395a604547f50b722d9 210 ProSitePatterns PS01196 Peptidyl-tRNA hydrolase signature 2. 109 119 - T 12-10-2018 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 VAPA_1c45170 457bbd737c563395a604547f50b722d9 210 Hamap MF_00083 Peptidyl-tRNA hydrolase [pth]. 2 180 34.358 T 12-10-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 VAPA_1c09250 8cd11a58d9b398aeb43f6d9cda5223a7 207 SMART SM00903 25 177 3.2E-11 T 12-10-2018 IPR002563 Flavin reductase like domain GO:0010181 VAPA_1c09250 8cd11a58d9b398aeb43f6d9cda5223a7 207 SUPERFAMILY SSF50475 5 192 2.06E-49 T 12-10-2018 VAPA_1c09250 8cd11a58d9b398aeb43f6d9cda5223a7 207 Pfam PF01613 Flavin reductase like domain 28 168 1.1E-14 T 12-10-2018 IPR002563 Flavin reductase like domain GO:0010181 VAPA_1c09250 8cd11a58d9b398aeb43f6d9cda5223a7 207 Gene3D G3DSA:2.30.110.10 18 207 1.6E-54 T 12-10-2018 IPR012349 FMN-binding split barrel GO:0048037 VAPA_1c49500 281daff4868756b9d85d4cdb40a62ad1 403 Pfam PF11306 Protein of unknown function (DUF3108) 232 395 3.1E-13 T 12-10-2018 IPR021457 Protein of unknown function DUF3108 VAPA_1c03000 145355be1ec8056a9808adaaa81cb63c 144 ProSitePatterns PS01117 MarR-type HTH domain signature. 66 100 - T 12-10-2018 IPR023187 Transcriptional regulator MarR-type, conserved site VAPA_1c03000 145355be1ec8056a9808adaaa81cb63c 144 SMART SM00347 27 127 2.1E-12 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 VAPA_1c03000 145355be1ec8056a9808adaaa81cb63c 144 Gene3D G3DSA:1.10.10.10 4 138 1.8E-28 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c03000 145355be1ec8056a9808adaaa81cb63c 144 Pfam PF01047 MarR family 34 91 1.1E-11 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 VAPA_1c03000 145355be1ec8056a9808adaaa81cb63c 144 SUPERFAMILY SSF46785 7 140 1.81E-26 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c03000 145355be1ec8056a9808adaaa81cb63c 144 TIGRFAM TIGR02337 HpaR: homoprotocatechuate degradation operon regulator, HpaR 9 138 1.1E-46 T 12-10-2018 IPR012712 Homoprotocatechuate degradation transcriptional regulator HpaR GO:0003677|GO:0010124|GO:0045892 VAPA_1c39110 134264bd2481b16082f7c6c036055322 272 Gene3D G3DSA:3.40.190.10 36 267 3.5E-93 T 12-10-2018 VAPA_1c39110 134264bd2481b16082f7c6c036055322 272 PIRSF PIRSF002854 1 272 5.5E-98 T 12-10-2018 IPR004872 Lipoprotein NlpA family VAPA_1c39110 134264bd2481b16082f7c6c036055322 272 Pfam PF03180 NLPA lipoprotein 35 272 9.4E-88 T 12-10-2018 IPR004872 Lipoprotein NlpA family VAPA_1c39110 134264bd2481b16082f7c6c036055322 272 SUPERFAMILY SSF53850 34 272 8.31E-80 T 12-10-2018 VAPA_1c39110 134264bd2481b16082f7c6c036055322 272 Gene3D G3DSA:3.40.190.10 116 223 3.5E-93 T 12-10-2018 VAPA_1c39110 134264bd2481b16082f7c6c036055322 272 TIGRFAM TIGR00363 TIGR00363: lipoprotein, YaeC family 28 270 3.1E-76 T 12-10-2018 IPR004872 Lipoprotein NlpA family VAPA_1c11360 e889e2cf5d14c2cf8954dac66ad9c4c1 213 Pfam PF11356 Type II secretion system protein C 21 124 2.8E-7 T 12-10-2018 IPR024961 Type II secretion system protein C, N-terminal VAPA_1c39450 5643018d5477d3f5bdfa530aee7e1498 267 Pfam PF01925 Sulfite exporter TauE/SafE 21 254 1.6E-24 T 12-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 VAPA_1c46310 65ce0be5491d6609dceb46ad27317b0c 517 Pfam PF02321 Outer membrane efflux protein 267 447 1.4E-17 T 12-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 VAPA_1c46310 65ce0be5491d6609dceb46ad27317b0c 517 Pfam PF02321 Outer membrane efflux protein 66 242 8.6E-13 T 12-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 VAPA_1c46310 65ce0be5491d6609dceb46ad27317b0c 517 SUPERFAMILY SSF56954 16 449 6.98E-48 T 12-10-2018 VAPA_1c46310 65ce0be5491d6609dceb46ad27317b0c 517 Gene3D G3DSA:1.20.1600.10 59 462 3.8E-43 T 12-10-2018 VAPA_2c00380 96602feca6a65ebeed6a64ac3529d2f1 302 Pfam PF04909 Amidohydrolase 120 301 4.5E-8 T 12-10-2018 IPR006680 Amidohydrolase-related GO:0016787 VAPA_2c00380 96602feca6a65ebeed6a64ac3529d2f1 302 Gene3D G3DSA:3.20.20.140 37 302 4.6E-24 T 12-10-2018 VAPA_2c00380 96602feca6a65ebeed6a64ac3529d2f1 302 SUPERFAMILY SSF51556 36 301 2.3E-22 T 12-10-2018 IPR032466 Metal-dependent hydrolase VAPA_1c04630 3a1c245fe69e4f6e150ccaf642c77ed8 328 TIGRFAM TIGR03558 oxido_grp_1: luciferase family oxidoreductase, group 1 4 322 8.5E-138 T 12-10-2018 IPR019949 Luciferase family oxidoreductase, group 1 VAPA_1c04630 3a1c245fe69e4f6e150ccaf642c77ed8 328 SUPERFAMILY SSF51679 2 322 2.75E-90 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 VAPA_1c04630 3a1c245fe69e4f6e150ccaf642c77ed8 328 Gene3D G3DSA:3.20.20.30 1 326 1.1E-102 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 VAPA_1c04630 3a1c245fe69e4f6e150ccaf642c77ed8 328 Pfam PF00296 Luciferase-like monooxygenase 13 300 9.6E-42 T 12-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 VAPA_1c19790 8af96b6f51dbc74e28f5fda43ac525b5 59 Pfam PF12244 Protein of unknown function (DUF3606) 4 57 3.6E-17 T 12-10-2018 IPR022037 Protein of unknown function DUF3606 VAPA_1c15910 f03f69bae342671255de0023f7808aab 243 SUPERFAMILY SSF51735 6 238 1.16E-61 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c15910 f03f69bae342671255de0023f7808aab 243 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 130 158 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 VAPA_1c15910 f03f69bae342671255de0023f7808aab 243 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 236 2.7E-44 T 12-10-2018 VAPA_1c15910 f03f69bae342671255de0023f7808aab 243 Gene3D G3DSA:3.40.50.720 1 240 1.5E-62 T 12-10-2018 VAPA_1c15910 f03f69bae342671255de0023f7808aab 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 71 82 2.2E-32 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c15910 f03f69bae342671255de0023f7808aab 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 164 181 2.2E-32 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c15910 f03f69bae342671255de0023f7808aab 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 2.2E-32 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c15910 f03f69bae342671255de0023f7808aab 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 200 220 2.2E-32 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c15910 f03f69bae342671255de0023f7808aab 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 118 134 2.2E-32 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c15910 f03f69bae342671255de0023f7808aab 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 143 162 2.2E-32 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c43840 fd4bed9686d2ae1f7dc46fd8cc28b91a 251 Hamap MF_01092 Cell division protein ZapD [zapD]. 1 250 31.604 T 12-10-2018 IPR009777 Cell division protein ZapD VAPA_1c43840 fd4bed9686d2ae1f7dc46fd8cc28b91a 251 Pfam PF07072 Cell division protein 16 226 4.7E-76 T 12-10-2018 IPR009777 Cell division protein ZapD VAPA_1c43840 fd4bed9686d2ae1f7dc46fd8cc28b91a 251 Gene3D G3DSA:2.60.440.10 3 250 7.7E-77 T 12-10-2018 IPR027462 Z ring-associated protein D, C-terminal VAPA_1c43840 fd4bed9686d2ae1f7dc46fd8cc28b91a 251 Gene3D G3DSA:1.10.3900.10 10 177 7.7E-77 T 12-10-2018 VAPA_1c43840 fd4bed9686d2ae1f7dc46fd8cc28b91a 251 SUPERFAMILY SSF160950 2 250 6.54E-85 T 12-10-2018 IPR036268 ZapD domain superfamily VAPA_1c27140 a9fbc1522b23a3e88f9d5fc6221975c3 194 Pfam PF07963 Prokaryotic N-terminal methylation motif 8 32 1.0E-4 T 12-10-2018 IPR012902 Prokaryotic N-terminal methylation site VAPA_1c40150 1bf014e1aa678a5f79daa2f1e3dee527 289 Pfam PF04909 Amidohydrolase 23 288 5.9E-32 T 12-10-2018 IPR006680 Amidohydrolase-related GO:0016787 VAPA_1c40150 1bf014e1aa678a5f79daa2f1e3dee527 289 Gene3D G3DSA:3.20.20.140 7 289 4.3E-72 T 12-10-2018 VAPA_1c40150 1bf014e1aa678a5f79daa2f1e3dee527 289 SUPERFAMILY SSF51556 19 288 1.09E-64 T 12-10-2018 IPR032466 Metal-dependent hydrolase VAPA_2c00210 3d7f6e069cde8fb580b6d5529c0a152d 332 Pfam PF03595 Voltage-dependent anion channel 23 322 5.3E-51 T 12-10-2018 IPR004695 Voltage-dependent anion channel GO:0016021|GO:0055085 VAPA_2c00210 3d7f6e069cde8fb580b6d5529c0a152d 332 Gene3D G3DSA:1.50.10.150 18 332 1.0E-83 T 12-10-2018 IPR038665 Voltage-dependent anion channel superfamily VAPA_1c42020 af4d4d5fd14eb6895c9e3be2732fdb48 298 Gene3D G3DSA:3.40.50.720 2 295 3.7E-61 T 12-10-2018 VAPA_1c42020 af4d4d5fd14eb6895c9e3be2732fdb48 298 Pfam PF00106 short chain dehydrogenase 4 192 6.3E-35 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c42020 af4d4d5fd14eb6895c9e3be2732fdb48 298 SUPERFAMILY SSF51735 2 203 7.61E-48 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c42020 af4d4d5fd14eb6895c9e3be2732fdb48 298 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 5.2E-16 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c42020 af4d4d5fd14eb6895c9e3be2732fdb48 298 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 5.2E-16 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c42020 af4d4d5fd14eb6895c9e3be2732fdb48 298 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 5.2E-16 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c42020 af4d4d5fd14eb6895c9e3be2732fdb48 298 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 5.2E-16 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c42020 af4d4d5fd14eb6895c9e3be2732fdb48 298 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 5.2E-16 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c42460 881496fbf8f04f6cc2fc5882bcb7a646 278 Hamap MF_01805 Segregation and condensation protein A [scpA]. 45 275 20.566 T 12-10-2018 IPR003768 Segregation and condensation protein A VAPA_1c42460 881496fbf8f04f6cc2fc5882bcb7a646 278 Pfam PF02616 Segregation and condensation protein ScpA 62 273 5.1E-29 T 12-10-2018 IPR003768 Segregation and condensation protein A VAPA_1c16820 a015e2ac3afef7cfa12c00f3677eb03d 490 Pfam PF07171 MlrC C-terminus 298 478 1.6E-55 T 12-10-2018 IPR010799 Microcystin LR degradation protein MlrC, C-terminal VAPA_1c16820 a015e2ac3afef7cfa12c00f3677eb03d 490 PIRSF PIRSF012702 1 490 1.4E-160 T 12-10-2018 IPR009197 Microcystin LR degradation protein MlrC VAPA_1c16820 a015e2ac3afef7cfa12c00f3677eb03d 490 Pfam PF07364 Metallopeptidase family M81 2 285 2.5E-89 T 12-10-2018 IPR015995 Microcystin LR degradation protein MlrC, N-terminal VAPA_1c08610 028280e1f0b62a0ed96b1e29d22639c8 445 Gene3D G3DSA:3.30.1330.120 263 391 1.2E-52 T 12-10-2018 VAPA_1c08610 028280e1f0b62a0ed96b1e29d22639c8 445 Pfam PF03972 MmgE/PrpD family 20 415 2.5E-56 T 12-10-2018 IPR005656 MmgE/PrpD GO:0016829 VAPA_1c08610 028280e1f0b62a0ed96b1e29d22639c8 445 SUPERFAMILY SSF103378 18 429 1.24E-55 T 12-10-2018 IPR036148 MmgE/PrpD superfamily GO:0016829 VAPA_1c08610 028280e1f0b62a0ed96b1e29d22639c8 445 Gene3D G3DSA:1.10.4100.10 32 407 1.2E-52 T 12-10-2018 VAPA_2c06960 789ce485a1e2fec80dff745aca04b007 96 Gene3D G3DSA:3.30.70.100 1 96 1.9E-26 T 12-10-2018 VAPA_2c06960 789ce485a1e2fec80dff745aca04b007 96 Pfam PF07045 Domain of unknown function (DUF1330) 3 96 2.9E-24 T 12-10-2018 IPR010753 Domain of unknown function DUF1330 VAPA_2c06960 789ce485a1e2fec80dff745aca04b007 96 SUPERFAMILY SSF54909 1 96 1.43E-22 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel VAPA_1c20680 b90905d8c890babfdee183aacb1c7323 281 Hamap MF_00056 2-dehydro-3-deoxyphosphooctonate aldolase [kdsA]. 11 275 47.261 T 12-10-2018 IPR006269 3-deoxy-8-phosphooctulonate synthase GO:0005737|GO:0008676 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 VAPA_1c20680 b90905d8c890babfdee183aacb1c7323 281 Pfam PF00793 DAHP synthetase I family 8 272 3.0E-65 T 12-10-2018 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 VAPA_1c20680 b90905d8c890babfdee183aacb1c7323 281 SUPERFAMILY SSF51569 6 277 2.66E-98 T 12-10-2018 VAPA_1c20680 b90905d8c890babfdee183aacb1c7323 281 TIGRFAM TIGR01362 KDO8P_synth: 3-deoxy-8-phosphooctulonate synthase 16 273 1.9E-111 T 12-10-2018 IPR006269 3-deoxy-8-phosphooctulonate synthase GO:0005737|GO:0008676 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 VAPA_1c20680 b90905d8c890babfdee183aacb1c7323 281 Gene3D G3DSA:3.20.20.70 1 281 7.4E-95 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 VAPA_1c39050 635ba175141cb2895fed8b37e896dadb 309 PRINTS PR00111 Alpha/beta hydrolase fold signature 58 73 2.8E-9 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 VAPA_1c39050 635ba175141cb2895fed8b37e896dadb 309 PRINTS PR00111 Alpha/beta hydrolase fold signature 122 135 2.8E-9 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 VAPA_1c39050 635ba175141cb2895fed8b37e896dadb 309 PRINTS PR00111 Alpha/beta hydrolase fold signature 108 121 2.8E-9 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 VAPA_1c39050 635ba175141cb2895fed8b37e896dadb 309 SUPERFAMILY SSF53474 7 308 4.31E-51 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c39050 635ba175141cb2895fed8b37e896dadb 309 PRINTS PR00412 Epoxide hydrolase signature 108 121 8.2E-8 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 VAPA_1c39050 635ba175141cb2895fed8b37e896dadb 309 PRINTS PR00412 Epoxide hydrolase signature 122 135 8.2E-8 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 VAPA_1c39050 635ba175141cb2895fed8b37e896dadb 309 PRINTS PR00412 Epoxide hydrolase signature 284 306 8.2E-8 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 VAPA_1c39050 635ba175141cb2895fed8b37e896dadb 309 PRINTS PR00412 Epoxide hydrolase signature 39 57 8.2E-8 T 12-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 VAPA_1c39050 635ba175141cb2895fed8b37e896dadb 309 Gene3D G3DSA:3.40.50.1820 8 303 2.2E-57 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c39050 635ba175141cb2895fed8b37e896dadb 309 Pfam PF12697 Alpha/beta hydrolase family 35 300 9.0E-24 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 VAPA_1c30300 801b780dfd50068665225b0c0aef21e6 205 SUPERFAMILY SSF51735 1 204 4.28E-35 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c30300 801b780dfd50068665225b0c0aef21e6 205 Pfam PF13460 NAD(P)H-binding 8 172 1.1E-29 T 12-10-2018 IPR016040 NAD(P)-binding domain VAPA_1c30300 801b780dfd50068665225b0c0aef21e6 205 Gene3D G3DSA:3.40.50.720 1 205 1.1E-48 T 12-10-2018 VAPA_1c10320 6255495176d81efd2e78d8525003f0ab 287 SUPERFAMILY SSF51197 7 287 2.84E-86 T 12-10-2018 VAPA_1c10320 6255495176d81efd2e78d8525003f0ab 287 Gene3D G3DSA:3.60.130.10 6 287 8.7E-88 T 12-10-2018 VAPA_1c10320 6255495176d81efd2e78d8525003f0ab 287 Pfam PF02668 Taurine catabolism dioxygenase TauD, TfdA family 9 280 3.8E-66 T 12-10-2018 IPR003819 TauD/TfdA-like domain GO:0016491|GO:0055114 Reactome: R-HSA-71262 VAPA_1c35300 d2e44cea50a9e54037f4ac5655d80bad 374 Pfam PF12706 Beta-lactamase superfamily domain 128 320 3.6E-44 T 12-10-2018 IPR001279 Metallo-beta-lactamase VAPA_1c35300 d2e44cea50a9e54037f4ac5655d80bad 374 SUPERFAMILY SSF56281 110 360 3.14E-35 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like VAPA_1c35300 d2e44cea50a9e54037f4ac5655d80bad 374 Gene3D G3DSA:3.60.15.10 94 370 1.6E-78 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like VAPA_2c01240 20d2f93db145ee04b1380e76269952d1 217 Gene3D G3DSA:1.20.1050.10 88 204 2.8E-41 T 12-10-2018 VAPA_2c01240 20d2f93db145ee04b1380e76269952d1 217 Pfam PF02798 Glutathione S-transferase, N-terminal domain 20 81 4.7E-12 T 12-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 VAPA_2c01240 20d2f93db145ee04b1380e76269952d1 217 SUPERFAMILY SSF47616 82 204 5.57E-21 T 12-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily VAPA_2c01240 20d2f93db145ee04b1380e76269952d1 217 SUPERFAMILY SSF52833 22 84 9.61E-16 T 12-10-2018 IPR036249 Thioredoxin-like superfamily VAPA_2c01240 20d2f93db145ee04b1380e76269952d1 217 Gene3D G3DSA:3.40.30.10 2 87 4.4E-34 T 12-10-2018 VAPA_1c10040 4f54fa5f2dfba17b706994280c6bd538 446 Pfam PF11906 Protein of unknown function (DUF3426) 296 442 1.7E-32 T 12-10-2018 IPR021834 Protein of unknown function DUF3426 VAPA_1c10040 4f54fa5f2dfba17b706994280c6bd538 446 TIGRFAM TIGR02098 MJ0042_CXXC: MJ0042 family finger-like domain 4 39 7.0E-14 T 12-10-2018 IPR011723 Zinc finger/thioredoxin putative VAPA_1c10040 4f54fa5f2dfba17b706994280c6bd538 446 Pfam PF13719 zinc-ribbon domain 3 39 1.9E-16 T 12-10-2018 IPR011723 Zinc finger/thioredoxin putative VAPA_2c10940 7d23ed93e028778d0053fca154754d9a 573 SUPERFAMILY SSF56059 121 437 2.77E-5 T 12-10-2018 VAPA_1c30700 3c1e32ea3704c4e915627b9161dc4c3c 407 Gene3D G3DSA:2.40.30.170 69 302 3.7E-61 T 12-10-2018 VAPA_1c30700 3c1e32ea3704c4e915627b9161dc4c3c 407 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 71 296 3.3E-18 T 12-10-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain VAPA_1c30700 3c1e32ea3704c4e915627b9161dc4c3c 407 Gene3D G3DSA:2.40.420.20 57 361 3.7E-61 T 12-10-2018 VAPA_1c30700 3c1e32ea3704c4e915627b9161dc4c3c 407 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 56 376 1.8E-66 T 12-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 VAPA_1c30700 3c1e32ea3704c4e915627b9161dc4c3c 407 Gene3D G3DSA:2.40.50.100 81 222 3.7E-61 T 12-10-2018 VAPA_1c30700 3c1e32ea3704c4e915627b9161dc4c3c 407 Gene3D G3DSA:1.10.287.470 120 187 3.7E-61 T 12-10-2018 VAPA_1c30700 3c1e32ea3704c4e915627b9161dc4c3c 407 SUPERFAMILY SSF111369 69 299 2.09E-22 T 12-10-2018 VAPA_2c10980 c67d3ba4eff3d7ab2b2b2a327fd424c8 176 SMART SM00972 115 173 3.4E-9 T 12-10-2018 IPR007893 Spore coat protein U VAPA_2c10980 c67d3ba4eff3d7ab2b2b2a327fd424c8 176 Pfam PF05229 Spore Coat Protein U domain 33 173 1.1E-27 T 12-10-2018 IPR007893 Spore coat protein U VAPA_1c21390 48e8c99643c6b04d8a070e43eb20b565 234 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 29 233 2.5E-50 T 12-10-2018 IPR011234 Fumarylacetoacetase-like, C-terminal GO:0003824 VAPA_1c21390 48e8c99643c6b04d8a070e43eb20b565 234 SUPERFAMILY SSF56529 21 233 1.83E-67 T 12-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 VAPA_1c21390 48e8c99643c6b04d8a070e43eb20b565 234 Gene3D G3DSA:3.90.850.10 2 234 1.9E-81 T 12-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 VAPA_1c30510 5fa68747d5b09bd27952abc5980ebcc2 285 SUPERFAMILY SSF48576 1 276 9.64E-65 T 12-10-2018 IPR008949 Isoprenoid synthase domain superfamily VAPA_1c30510 5fa68747d5b09bd27952abc5980ebcc2 285 TIGRFAM TIGR03464 HpnC: squalene synthase HpnC 1 271 1.6E-89 T 12-10-2018 IPR017827 Hydroxysqualene synthase HpnC MetaCyc: PWY-7072 VAPA_1c30510 5fa68747d5b09bd27952abc5980ebcc2 285 Gene3D G3DSA:1.10.600.10 1 252 5.1E-66 T 12-10-2018 IPR008949 Isoprenoid synthase domain superfamily VAPA_1c30510 5fa68747d5b09bd27952abc5980ebcc2 285 Pfam PF00494 Squalene/phytoene synthase 1 260 8.2E-51 T 12-10-2018 VAPA_1c35470 3214840d14820cece54e1cab5a02be94 148 Pfam PF00692 dUTPase 15 146 7.2E-35 T 12-10-2018 IPR029054 dUTPase-like VAPA_1c35470 3214840d14820cece54e1cab5a02be94 148 Gene3D G3DSA:2.70.40.10 1 148 2.3E-48 T 12-10-2018 IPR036157 dUTPase-like superfamily VAPA_1c35470 3214840d14820cece54e1cab5a02be94 148 Hamap MF_00116 Deoxyuridine 5'-triphosphate nucleotidohydrolase [dut]. 5 147 31.83 T 12-10-2018 IPR008181 Deoxyuridine triphosphate nucleotidohydrolase GO:0004170|GO:0046080 KEGG: 00240+3.6.1.23|KEGG: 00983+3.6.1.23 VAPA_1c35470 3214840d14820cece54e1cab5a02be94 148 TIGRFAM TIGR00576 dut: dUTP diphosphatase 14 147 4.2E-45 T 12-10-2018 IPR008181 Deoxyuridine triphosphate nucleotidohydrolase GO:0004170|GO:0046080 KEGG: 00240+3.6.1.23|KEGG: 00983+3.6.1.23 VAPA_1c35470 3214840d14820cece54e1cab5a02be94 148 SUPERFAMILY SSF51283 15 147 1.31E-48 T 12-10-2018 IPR036157 dUTPase-like superfamily VAPA_1c48070 2029d716b65565b6b18dde2b31a503f2 317 Pfam PF01148 Cytidylyltransferase family 49 313 5.7E-66 T 12-10-2018 VAPA_1c40350 e2d968ad629da7d95460bd73ee386e54 217 PIRSF PIRSF000005 2 209 1.3E-39 T 12-10-2018 IPR024167 Cytochrome c4-like GO:0005506|GO:0009055|GO:0020037|GO:0042597 VAPA_1c40350 e2d968ad629da7d95460bd73ee386e54 217 SUPERFAMILY SSF46626 115 206 8.17E-17 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 VAPA_1c40350 e2d968ad629da7d95460bd73ee386e54 217 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 40 109 2.9E-7 T 12-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 VAPA_1c40350 e2d968ad629da7d95460bd73ee386e54 217 Gene3D G3DSA:1.10.760.10 38 112 1.5E-19 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 VAPA_1c40350 e2d968ad629da7d95460bd73ee386e54 217 Gene3D G3DSA:1.10.760.10 119 206 1.4E-16 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 VAPA_1c40350 e2d968ad629da7d95460bd73ee386e54 217 SUPERFAMILY SSF46626 29 111 1.29E-17 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 VAPA_1c02090 ea1d8342ccb2a2651261fb844fb4da53 324 SUPERFAMILY SSF53448 14 250 2.13E-28 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases VAPA_1c02090 ea1d8342ccb2a2651261fb844fb4da53 324 Gene3D G3DSA:3.90.550.10 2 245 1.3E-42 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases VAPA_1c02090 ea1d8342ccb2a2651261fb844fb4da53 324 Pfam PF00535 Glycosyl transferase family 2 18 173 3.6E-17 T 12-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 VAPA_1c22120 9acf9ca5c01a41f70399e8f6dd187cf2 243 Gene3D G3DSA:3.40.109.10 6 231 1.4E-62 T 12-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 VAPA_1c22120 9acf9ca5c01a41f70399e8f6dd187cf2 243 SUPERFAMILY SSF55469 16 234 1.03E-47 T 12-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 VAPA_1c22120 9acf9ca5c01a41f70399e8f6dd187cf2 243 Pfam PF00881 Nitroreductase family 19 211 3.5E-35 T 12-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 VAPA_1c28060 c924d6773709d12922acebcd88b28641 309 SUPERFAMILY SSF103481 197 287 1.83E-5 T 12-10-2018 VAPA_1c28060 c924d6773709d12922acebcd88b28641 309 SUPERFAMILY SSF103481 46 142 8.63E-8 T 12-10-2018 VAPA_1c28060 c924d6773709d12922acebcd88b28641 309 Pfam PF00892 EamA-like transporter family 10 141 8.4E-13 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 VAPA_1c28060 c924d6773709d12922acebcd88b28641 309 Pfam PF00892 EamA-like transporter family 157 287 8.6E-9 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 VAPA_1c05010 849619a346ca2532673c630135d81881 325 SUPERFAMILY SSF53850 115 279 3.26E-10 T 12-10-2018 VAPA_1c05010 849619a346ca2532673c630135d81881 325 Gene3D G3DSA:3.40.190.150 30 315 1.8E-95 T 12-10-2018 VAPA_1c05010 849619a346ca2532673c630135d81881 325 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 48 321 3.0E-74 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c05010 849619a346ca2532673c630135d81881 325 PIRSF PIRSF017082 1 325 9.2E-69 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c05010 849619a346ca2532673c630135d81881 325 Gene3D G3DSA:3.40.190.10 126 250 1.8E-95 T 12-10-2018 VAPA_1c02930 951fde6842259a08709f9e012811b2bb 273 TIGRFAM TIGR02311 HpaI: 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase 6 262 1.2E-111 T 12-10-2018 IPR012689 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase GO:0010124|GO:0018802 KEGG: 00350+4.1.2.52 VAPA_1c02930 951fde6842259a08709f9e012811b2bb 273 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 18 251 4.9E-59 T 12-10-2018 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 VAPA_1c02930 951fde6842259a08709f9e012811b2bb 273 Gene3D G3DSA:3.20.20.60 1 273 2.9E-93 T 12-10-2018 VAPA_1c02930 951fde6842259a08709f9e012811b2bb 273 SUPERFAMILY SSF51621 2 264 4.89E-85 T 12-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 VAPA_1c13240 70b7a6bd60ff1792cbcadff462f15f1d 327 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 143 164 - T 12-10-2018 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 VAPA_1c13240 70b7a6bd60ff1792cbcadff462f15f1d 327 SUPERFAMILY SSF50129 3 138 2.52E-35 T 12-10-2018 IPR011032 GroES-like superfamily VAPA_1c13240 70b7a6bd60ff1792cbcadff462f15f1d 327 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 130 3.6E-9 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 VAPA_1c13240 70b7a6bd60ff1792cbcadff462f15f1d 327 SUPERFAMILY SSF51735 112 268 5.53E-46 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c13240 70b7a6bd60ff1792cbcadff462f15f1d 327 Pfam PF00107 Zinc-binding dehydrogenase 154 260 1.1E-28 T 12-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 VAPA_1c13240 70b7a6bd60ff1792cbcadff462f15f1d 327 Gene3D G3DSA:3.40.50.720 123 271 8.2E-114 T 12-10-2018 VAPA_1c13240 70b7a6bd60ff1792cbcadff462f15f1d 327 Gene3D G3DSA:3.90.180.10 12 321 8.2E-114 T 12-10-2018 VAPA_1c13240 70b7a6bd60ff1792cbcadff462f15f1d 327 SMART SM00829 11 325 2.8E-27 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 VAPA_1c23130 3b7270f1e62a35b4ef7c7c6b10704c98 139 TIGRFAM TIGR01999 iscU: FeS cluster assembly scaffold IscU 3 126 1.2E-66 T 12-10-2018 IPR011339 ISC system FeS cluster assembly, IscU scaffold GO:0005506|GO:0016226|GO:0051536 Reactome: R-HSA-1362409 VAPA_1c23130 3b7270f1e62a35b4ef7c7c6b10704c98 139 Pfam PF01592 NifU-like N terminal domain 2 127 5.8E-57 T 12-10-2018 IPR002871 NIF system FeS cluster assembly, NifU, N-terminal GO:0005506|GO:0016226|GO:0051536 Reactome: R-HSA-1362409 VAPA_1c23130 3b7270f1e62a35b4ef7c7c6b10704c98 139 Gene3D G3DSA:3.90.1010.10 1 134 1.3E-57 T 12-10-2018 VAPA_1c23130 3b7270f1e62a35b4ef7c7c6b10704c98 139 SUPERFAMILY SSF82649 1 128 3.14E-47 T 12-10-2018 VAPA_1c12340 6b49d979ca3a594e9a9d62e35667eff0 259 SUPERFAMILY SSF51366 1 258 8.63E-84 T 12-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 VAPA_1c12340 6b49d979ca3a594e9a9d62e35667eff0 259 Pfam PF00977 Histidine biosynthesis protein 5 241 1.2E-88 T 12-10-2018 IPR006062 Histidine biosynthesis GO:0000105 VAPA_1c12340 6b49d979ca3a594e9a9d62e35667eff0 259 TIGRFAM TIGR00735 hisF: imidazoleglycerol phosphate synthase, cyclase subunit 1 258 1.1E-109 T 12-10-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 VAPA_1c12340 6b49d979ca3a594e9a9d62e35667eff0 259 Gene3D G3DSA:3.20.20.70 1 259 1.8E-107 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 VAPA_1c12340 6b49d979ca3a594e9a9d62e35667eff0 259 Hamap MF_01013 Imidazole glycerol phosphate synthase subunit HisF [hisF]. 1 258 48.239 T 12-10-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 VAPA_1c27520 35f4b53952cacd2c20863a68fd86d5ab 126 Gene3D G3DSA:3.40.50.2300 2 125 1.7E-23 T 12-10-2018 VAPA_1c27520 35f4b53952cacd2c20863a68fd86d5ab 126 SMART SM00448 8 122 7.1E-19 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_1c27520 35f4b53952cacd2c20863a68fd86d5ab 126 Pfam PF00072 Response regulator receiver domain 10 122 1.8E-15 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_1c27520 35f4b53952cacd2c20863a68fd86d5ab 126 SUPERFAMILY SSF52172 6 123 4.84E-25 T 12-10-2018 IPR011006 CheY-like superfamily VAPA_2c07670 b94cdf726c03f967c5f9dd0a0a1a93bb 751 SMART SM01008 237 320 1.6E-12 T 12-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead VAPA_2c07670 b94cdf726c03f967c5f9dd0a0a1a93bb 751 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 623 703 7.5E-9 T 12-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 VAPA_2c07670 b94cdf726c03f967c5f9dd0a0a1a93bb 751 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 351 582 2.6E-29 T 12-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 VAPA_2c07670 b94cdf726c03f967c5f9dd0a0a1a93bb 751 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 62 213 6.8E-12 T 12-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 VAPA_2c07670 b94cdf726c03f967c5f9dd0a0a1a93bb 751 Gene3D G3DSA:3.30.365.10 370 468 4.5E-53 T 12-10-2018 VAPA_2c07670 b94cdf726c03f967c5f9dd0a0a1a93bb 751 Gene3D G3DSA:3.30.365.10 352 580 4.5E-53 T 12-10-2018 VAPA_2c07670 b94cdf726c03f967c5f9dd0a0a1a93bb 751 Gene3D G3DSA:3.30.365.10 609 751 5.6E-29 T 12-10-2018 VAPA_2c07670 b94cdf726c03f967c5f9dd0a0a1a93bb 751 Gene3D G3DSA:3.30.365.10 69 208 3.4E-19 T 12-10-2018 VAPA_2c07670 b94cdf726c03f967c5f9dd0a0a1a93bb 751 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 34 57 8.8E-4 T 12-10-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal VAPA_2c07670 b94cdf726c03f967c5f9dd0a0a1a93bb 751 Gene3D G3DSA:3.90.1170.50 209 304 1.0E-10 T 12-10-2018 VAPA_2c07670 b94cdf726c03f967c5f9dd0a0a1a93bb 751 SUPERFAMILY SSF56003 351 748 6.02E-107 T 12-10-2018 IPR037165 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain superfamily GO:0016491|GO:0055114 VAPA_2c07670 b94cdf726c03f967c5f9dd0a0a1a93bb 751 SUPERFAMILY SSF56003 72 271 7.32E-40 T 12-10-2018 IPR037165 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain superfamily GO:0016491|GO:0055114 VAPA_2c07670 b94cdf726c03f967c5f9dd0a0a1a93bb 751 PIRSF PIRSF036389 22 751 3.8E-228 T 12-10-2018 IPR012368 Oxidoreductase molybdopterin-binding subunit, IorB-related VAPA_1c37370 c59c3619be6081ba3e98398ab3aeb1a8 604 SUPERFAMILY SSF50715 387 600 1.41E-60 T 12-10-2018 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain superfamily GO:0006412 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 VAPA_1c37370 c59c3619be6081ba3e98398ab3aeb1a8 604 Pfam PF03950 tRNA synthetases class I (E and Q), anti-codon binding domain 387 581 1.1E-48 T 12-10-2018 IPR020059 Glutamyl/glutaminyl-tRNA synthetase, class Ib, anti-codon binding domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 VAPA_1c37370 c59c3619be6081ba3e98398ab3aeb1a8 604 Gene3D G3DSA:2.40.240.10 389 598 1.3E-66 T 12-10-2018 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, N-terminal Reactome: R-HSA-2408517|Reactome: R-HSA-379716 VAPA_1c37370 c59c3619be6081ba3e98398ab3aeb1a8 604 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 57 383 1.4E-96 T 12-10-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0004812|GO:0005524|GO:0043039 VAPA_1c37370 c59c3619be6081ba3e98398ab3aeb1a8 604 SUPERFAMILY SSF52374 57 393 1.54E-91 T 12-10-2018 VAPA_1c37370 c59c3619be6081ba3e98398ab3aeb1a8 604 PRINTS PR00987 Glutamyl-tRNA synthetase signature 90 103 7.9E-11 T 12-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 VAPA_1c37370 c59c3619be6081ba3e98398ab3aeb1a8 604 PRINTS PR00987 Glutamyl-tRNA synthetase signature 61 73 7.9E-11 T 12-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 VAPA_1c37370 c59c3619be6081ba3e98398ab3aeb1a8 604 PRINTS PR00987 Glutamyl-tRNA synthetase signature 252 262 7.9E-11 T 12-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 VAPA_1c37370 c59c3619be6081ba3e98398ab3aeb1a8 604 PRINTS PR00987 Glutamyl-tRNA synthetase signature 75 86 7.9E-11 T 12-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 VAPA_1c37370 c59c3619be6081ba3e98398ab3aeb1a8 604 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 64 75 - T 12-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 VAPA_1c37370 c59c3619be6081ba3e98398ab3aeb1a8 604 Gene3D G3DSA:3.40.50.620 41 388 5.9E-128 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold VAPA_1c37370 c59c3619be6081ba3e98398ab3aeb1a8 604 TIGRFAM TIGR00440 glnS: glutamine--tRNA ligase 58 604 1.8E-198 T 12-10-2018 IPR004514 Glutamine-tRNA synthetase GO:0000166|GO:0004819|GO:0005524|GO:0005737|GO:0006425 KEGG: 00970+6.1.1.18|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 VAPA_1c37370 c59c3619be6081ba3e98398ab3aeb1a8 604 Gene3D G3DSA:2.40.240.10 395 519 1.3E-66 T 12-10-2018 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, N-terminal Reactome: R-HSA-2408517|Reactome: R-HSA-379716 VAPA_1c28250 05d29346c318bb866255c22dcda8835b 130 SUPERFAMILY SSF52172 7 117 3.98E-16 T 12-10-2018 IPR011006 CheY-like superfamily VAPA_1c28250 05d29346c318bb866255c22dcda8835b 130 SMART SM00448 3 118 2.4E-8 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_1c28250 05d29346c318bb866255c22dcda8835b 130 Gene3D G3DSA:3.40.50.2300 5 122 1.1E-13 T 12-10-2018 VAPA_1c28250 05d29346c318bb866255c22dcda8835b 130 Pfam PF00072 Response regulator receiver domain 6 116 3.7E-11 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_2c04510 f717a218557cf2c5c5831b68d51c09c4 264 SUPERFAMILY SSF103501 1 226 1.01E-65 T 12-10-2018 IPR036197 NarG-like superfamily VAPA_2c04510 f717a218557cf2c5c5831b68d51c09c4 264 TIGRFAM TIGR00351 narI: respiratory nitrate reductase, gamma subunit 3 227 1.9E-82 T 12-10-2018 IPR003816 Nitrate reductase, gamma subunit GO:0008940|GO:0009325|GO:0055114 VAPA_2c04510 f717a218557cf2c5c5831b68d51c09c4 264 Pfam PF02665 Nitrate reductase gamma subunit 6 226 8.8E-82 T 12-10-2018 IPR023234 NarG-like domain VAPA_2c04510 f717a218557cf2c5c5831b68d51c09c4 264 Gene3D G3DSA:1.20.950.20 1 218 6.7E-75 T 12-10-2018 VAPA_1c36940 abb760f2ca4969b81960a683e652a730 330 SUPERFAMILY SSF53850 118 295 8.58E-6 T 12-10-2018 VAPA_1c36940 abb760f2ca4969b81960a683e652a730 330 Gene3D G3DSA:3.40.190.10 134 256 1.3E-86 T 12-10-2018 VAPA_1c36940 abb760f2ca4969b81960a683e652a730 330 PIRSF PIRSF017082 1 329 3.0E-65 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c36940 abb760f2ca4969b81960a683e652a730 330 Gene3D G3DSA:3.40.190.150 38 321 1.3E-86 T 12-10-2018 VAPA_1c36940 abb760f2ca4969b81960a683e652a730 330 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 55 327 1.5E-55 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c15750 71442c9937d2819eef1a28a7372cf7bc 198 Gene3D G3DSA:3.30.420.10 14 196 2.9E-68 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 VAPA_1c15750 71442c9937d2819eef1a28a7372cf7bc 198 SUPERFAMILY SSF53098 19 195 1.64E-43 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily VAPA_1c15750 71442c9937d2819eef1a28a7372cf7bc 198 Pfam PF00929 Exonuclease 24 185 5.6E-29 T 12-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III VAPA_1c15750 71442c9937d2819eef1a28a7372cf7bc 198 Hamap MF_00045 Oligoribonuclease [orn]. 18 196 40.677 T 12-10-2018 IPR022894 Oligoribonuclease GO:0000175 VAPA_1c15750 71442c9937d2819eef1a28a7372cf7bc 198 SMART SM00479 22 195 2.7E-20 T 12-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III VAPA_1c40720 30200f82173413303f0c57d75db517f8 175 Gene3D G3DSA:2.60.120.10 23 175 2.4E-54 T 12-10-2018 IPR014710 RmlC-like jelly roll fold VAPA_1c40720 30200f82173413303f0c57d75db517f8 175 SUPERFAMILY SSF51182 30 157 2.77E-28 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily VAPA_1c40720 30200f82173413303f0c57d75db517f8 175 Pfam PF12973 ChrR Cupin-like domain 39 126 4.2E-17 T 12-10-2018 IPR025979 ChrR-like cupin domain VAPA_1c01030 e9fa9eba5b956306c9af8f0dd1e39e59 153 Pfam PF02082 Transcriptional regulator 1 81 1.1E-20 T 12-10-2018 IPR000944 Transcription regulator Rrf2-type VAPA_1c01030 e9fa9eba5b956306c9af8f0dd1e39e59 153 SUPERFAMILY SSF46785 4 136 1.25E-28 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c01030 e9fa9eba5b956306c9af8f0dd1e39e59 153 Gene3D G3DSA:1.10.10.10 1 149 2.5E-38 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c32910 0e8255f83ebd714ff5c3319b173acccd 325 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 233 1.1E-73 T 12-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 VAPA_1c32910 0e8255f83ebd714ff5c3319b173acccd 325 Hamap MF_00956 GDP-L-fucose synthase [fcl]. 1 314 45.108 T 12-10-2018 IPR028614 GDP-L-fucose synthase/GDP-L-colitose synthase GO:0009226|GO:0016491 KEGG: 00051+1.1.1.271|KEGG: 00520+1.1.1.271|MetaCyc: PWY-66|Reactome: R-HSA-6787639 VAPA_1c32910 0e8255f83ebd714ff5c3319b173acccd 325 SUPERFAMILY SSF51735 1 315 2.47E-73 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c32910 0e8255f83ebd714ff5c3319b173acccd 325 Gene3D G3DSA:3.90.25.10 168 310 4.0E-104 T 12-10-2018 VAPA_1c32910 0e8255f83ebd714ff5c3319b173acccd 325 Gene3D G3DSA:3.40.50.720 3 303 4.0E-104 T 12-10-2018 VAPA_1c01280 aaa33f55747f9109b06587fd12791e52 412 Gene3D G3DSA:3.30.1540.10 246 337 2.2E-141 T 12-10-2018 VAPA_1c01280 aaa33f55747f9109b06587fd12791e52 412 Gene3D G3DSA:3.40.50.10540 8 406 2.2E-141 T 12-10-2018 IPR023606 CoA-transferase family III domain superfamily VAPA_1c01280 aaa33f55747f9109b06587fd12791e52 412 Pfam PF02515 CoA-transferase family III 8 389 1.4E-129 T 12-10-2018 IPR003673 CoA-transferase family III GO:0003824 VAPA_1c01280 aaa33f55747f9109b06587fd12791e52 412 SUPERFAMILY SSF89796 7 412 8.37E-141 T 12-10-2018 IPR023606 CoA-transferase family III domain superfamily VAPA_1c00180 0c1106a12c1fc98509c8631d000b4e1e 250 Pfam PF00583 Acetyltransferase (GNAT) family 153 234 1.8E-9 T 12-10-2018 IPR000182 GNAT domain VAPA_1c00180 0c1106a12c1fc98509c8631d000b4e1e 250 SUPERFAMILY SSF55729 115 244 1.52E-16 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase VAPA_1c00180 0c1106a12c1fc98509c8631d000b4e1e 250 Gene3D G3DSA:3.40.630.30 5 247 1.3E-23 T 12-10-2018 VAPA_2c11890 e273959aba0cd748d8eb8352541960d7 437 Pfam PF13701 Transposase DDE domain group 1 14 435 3.2E-149 T 12-10-2018 IPR025668 Transposase DDE domain VAPA_1c37030 b180fbbf03f21294068d1b981a5c2846 199 Gene3D G3DSA:1.10.10.10 40 145 5.8E-24 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c37030 b180fbbf03f21294068d1b981a5c2846 199 Pfam PF03551 Transcriptional regulator PadR-like family 57 127 4.6E-17 T 12-10-2018 IPR005149 Transcription regulator PadR, N-terminal VAPA_1c37030 b180fbbf03f21294068d1b981a5c2846 199 SUPERFAMILY SSF46785 53 144 2.05E-23 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c26350 9475254e8d50b78346e0653dff0c63ed 264 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 167 186 9.7E-14 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c26350 9475254e8d50b78346e0653dff0c63ed 264 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 144 152 9.7E-14 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c26350 9475254e8d50b78346e0653dff0c63ed 264 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 90 101 9.7E-14 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c26350 9475254e8d50b78346e0653dff0c63ed 264 SUPERFAMILY SSF51735 14 260 1.67E-79 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c26350 9475254e8d50b78346e0653dff0c63ed 264 Pfam PF00106 short chain dehydrogenase 15 207 5.4E-57 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c26350 9475254e8d50b78346e0653dff0c63ed 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 222 242 2.4E-40 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c26350 9475254e8d50b78346e0653dff0c63ed 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 138 154 2.4E-40 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c26350 9475254e8d50b78346e0653dff0c63ed 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 90 101 2.4E-40 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c26350 9475254e8d50b78346e0653dff0c63ed 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 188 205 2.4E-40 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c26350 9475254e8d50b78346e0653dff0c63ed 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 16 33 2.4E-40 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c26350 9475254e8d50b78346e0653dff0c63ed 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 167 186 2.4E-40 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c26350 9475254e8d50b78346e0653dff0c63ed 264 Gene3D G3DSA:3.40.50.720 1 262 8.1E-82 T 12-10-2018 VAPA_2c05440 d0ff165beba802d4e73f78422eb9f07b 307 Pfam PF00146 NADH dehydrogenase 12 288 3.9E-24 T 12-10-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VAPA_1c40000 f290e94534bd5fc8d641393aebc19a8b 201 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 146 163 1.4E-13 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c40000 f290e94534bd5fc8d641393aebc19a8b 201 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 55 66 1.4E-13 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c40000 f290e94534bd5fc8d641393aebc19a8b 201 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 100 116 1.4E-13 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c40000 f290e94534bd5fc8d641393aebc19a8b 201 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 2 19 1.4E-13 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c40000 f290e94534bd5fc8d641393aebc19a8b 201 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 126 145 1.4E-13 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c40000 f290e94534bd5fc8d641393aebc19a8b 201 Gene3D G3DSA:3.40.50.720 1 200 5.0E-39 T 12-10-2018 VAPA_1c40000 f290e94534bd5fc8d641393aebc19a8b 201 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 21 171 7.9E-15 T 12-10-2018 VAPA_1c40000 f290e94534bd5fc8d641393aebc19a8b 201 SUPERFAMILY SSF51735 1 198 1.11E-28 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_2c05360 6abaa837b568ca5de0c0bdd72512197d 315 Pfam PF00146 NADH dehydrogenase 13 309 3.8E-33 T 12-10-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VAPA_1c48380 984e20f5858c53c97001f05bdb05ec50 426 Pfam PF13657 HipA N-terminal domain 35 121 1.3E-7 T 12-10-2018 IPR017508 HipA, N-terminal subdomain 1 VAPA_1c48380 984e20f5858c53c97001f05bdb05ec50 426 Pfam PF07804 HipA-like C-terminal domain 173 392 1.0E-47 T 12-10-2018 IPR012893 HipA-like, C-terminal VAPA_1c39460 b17f5553aa13f2a2a8da5cb51f7d6b53 340 PIRSF PIRSF028415 9 105 4.1E-6 T 12-10-2018 IPR014545 Uncharacterised conserved protein UCP028415 VAPA_1c39460 b17f5553aa13f2a2a8da5cb51f7d6b53 340 PIRSF PIRSF028415 136 324 8.6E-18 T 12-10-2018 IPR014545 Uncharacterised conserved protein UCP028415 VAPA_1c39460 b17f5553aa13f2a2a8da5cb51f7d6b53 340 Pfam PF10030 Uncharacterized protein conserved in bacteria (DUF2272) 161 338 3.9E-23 T 12-10-2018 IPR019262 Domain of unknown function DUF2272 VAPA_2c12850 b7a50d9900020d37cee0e19ad809b332 410 Pfam PF07804 HipA-like C-terminal domain 147 357 1.8E-41 T 12-10-2018 IPR012893 HipA-like, C-terminal VAPA_2c12850 b7a50d9900020d37cee0e19ad809b332 410 Pfam PF13657 HipA N-terminal domain 16 104 9.6E-8 T 12-10-2018 IPR017508 HipA, N-terminal subdomain 1 VAPA_1c53370 96a6910aad0cad50ec855e2d05bf6210 307 Gene3D G3DSA:1.10.1040.10 174 298 4.3E-42 T 12-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 VAPA_1c53370 96a6910aad0cad50ec855e2d05bf6210 307 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 175 294 6.8E-37 T 12-10-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 VAPA_1c53370 96a6910aad0cad50ec855e2d05bf6210 307 Gene3D G3DSA:3.40.50.720 3 173 2.0E-44 T 12-10-2018 VAPA_1c53370 96a6910aad0cad50ec855e2d05bf6210 307 PIRSF PIRSF000103 2 298 3.6E-62 T 12-10-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 VAPA_1c53370 96a6910aad0cad50ec855e2d05bf6210 307 SUPERFAMILY SSF48179 174 296 3.97E-37 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 VAPA_1c53370 96a6910aad0cad50ec855e2d05bf6210 307 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 10 169 3.6E-37 T 12-10-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 VAPA_1c53370 96a6910aad0cad50ec855e2d05bf6210 307 ProSitePatterns PS00895 3-hydroxyisobutyrate dehydrogenase signature. 12 25 - T 12-10-2018 IPR002204 3-hydroxyisobutyrate dehydrogenase-related, conserved site GO:0016491|GO:0055114 Reactome: R-HSA-70895 VAPA_1c53370 96a6910aad0cad50ec855e2d05bf6210 307 SUPERFAMILY SSF51735 10 172 1.32E-36 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c19880 baecd1c2705411ea5ecac15deea38ed9 164 Gene3D G3DSA:3.40.630.30 5 135 2.1E-21 T 12-10-2018 VAPA_1c19880 baecd1c2705411ea5ecac15deea38ed9 164 SUPERFAMILY SSF55729 6 116 2.23E-16 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase VAPA_1c19880 baecd1c2705411ea5ecac15deea38ed9 164 Pfam PF00583 Acetyltransferase (GNAT) family 35 110 1.7E-7 T 12-10-2018 IPR000182 GNAT domain VAPA_1c27990 b66b93db91f0ddab4181aa45ebbf077e 111 Gene3D G3DSA:3.10.20.280 1 88 4.4E-22 T 12-10-2018 IPR037021 RnfH superfamily VAPA_1c27990 b66b93db91f0ddab4181aa45ebbf077e 111 Hamap MF_00460 Protein RnfH [rnfH]. 2 94 19.234 T 12-10-2018 IPR005346 RnfH protein VAPA_1c27990 b66b93db91f0ddab4181aa45ebbf077e 111 SUPERFAMILY SSF54285 2 77 2.13E-16 T 12-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp VAPA_1c27990 b66b93db91f0ddab4181aa45ebbf077e 111 Pfam PF03658 RnfH family Ubiquitin 4 86 1.9E-21 T 12-10-2018 IPR005346 RnfH protein VAPA_1c47570 729110e082acbc23b9822dbab3d0a33f 149 Pfam PF03652 Holliday junction resolvase 26 146 1.7E-30 T 12-10-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 VAPA_1c47570 729110e082acbc23b9822dbab3d0a33f 149 SMART SM00732 25 124 1.4E-23 T 12-10-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 VAPA_1c47570 729110e082acbc23b9822dbab3d0a33f 149 Hamap MF_00651 Putative pre-16S rRNA nuclease [yqgF]. 25 149 19.557 T 12-10-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 VAPA_1c47570 729110e082acbc23b9822dbab3d0a33f 149 TIGRFAM TIGR00250 RNAse_H_YqgF: putative transcription antitermination factor YqgF 28 145 5.0E-26 T 12-10-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 VAPA_1c47570 729110e082acbc23b9822dbab3d0a33f 149 SUPERFAMILY SSF53098 26 148 1.18E-30 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily VAPA_1c47570 729110e082acbc23b9822dbab3d0a33f 149 Gene3D G3DSA:3.30.420.140 24 147 4.0E-30 T 12-10-2018 IPR037027 YqgF/RNase H-like domain superfamily GO:0006139 VAPA_2c04620 6c6d23f3f67b64dcd19a0fae00417a27 192 SUPERFAMILY SSF53671 18 153 3.93E-10 T 12-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 VAPA_2c04620 6c6d23f3f67b64dcd19a0fae00417a27 192 Gene3D G3DSA:3.40.50.1370 14 167 1.8E-17 T 12-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 VAPA_2c04620 6c6d23f3f67b64dcd19a0fae00417a27 192 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 21 152 1.1E-7 T 12-10-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 VAPA_1c04080 618671a7355912eb4d8b1b0a2045f874 326 Pfam PF02653 Branched-chain amino acid transport system / permease component 53 317 3.1E-52 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 VAPA_1c25040 41f47778d95c8bd21ca86d903b2bd580 298 Pfam PF11304 Protein of unknown function (DUF3106) 79 179 1.1E-29 T 12-10-2018 IPR021455 Protein of unknown function DUF3106 VAPA_1c21580 abadb44534431849499dfa4c0a793c40 113 Pfam PF06476 Protein of unknown function (DUF1090) 26 105 9.6E-9 T 12-10-2018 IPR009468 Protein of unknown function DUF1090 VAPA_2c10630 277d4c07bd51691a16a80cfde3e787ae 217 Pfam PF00857 Isochorismatase family 20 170 7.9E-26 T 12-10-2018 IPR000868 Isochorismatase-like GO:0003824 VAPA_2c10630 277d4c07bd51691a16a80cfde3e787ae 217 Gene3D G3DSA:3.40.50.850 10 209 2.3E-41 T 12-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 VAPA_2c10630 277d4c07bd51691a16a80cfde3e787ae 217 SUPERFAMILY SSF52499 13 210 2.62E-45 T 12-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 VAPA_2c02630 884a6878149b49a66105066a28ae5ee2 221 TIGRFAM TIGR01493 HAD-SF-IA-v2: HAD hydrolase, family IA, variant 2 7 182 2.0E-13 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 VAPA_2c02630 884a6878149b49a66105066a28ae5ee2 221 Gene3D G3DSA:3.40.50.1000 6 201 1.3E-43 T 12-10-2018 IPR023214 HAD superfamily VAPA_2c02630 884a6878149b49a66105066a28ae5ee2 221 SUPERFAMILY SSF56784 5 219 3.96E-37 T 12-10-2018 IPR036412 HAD-like superfamily VAPA_2c02630 884a6878149b49a66105066a28ae5ee2 221 TIGRFAM TIGR01428 HAD_type_II: haloacid dehalogenase, type II 6 199 2.1E-48 T 12-10-2018 IPR006328 L-2-Haloacid dehalogenase GO:0019120 KEGG: 00361+3.8.1.2|KEGG: 00625+3.8.1.2|MetaCyc: PWY-7425 VAPA_2c02630 884a6878149b49a66105066a28ae5ee2 221 Pfam PF13419 Haloacid dehalogenase-like hydrolase 92 187 3.1E-9 T 12-10-2018 VAPA_2c02630 884a6878149b49a66105066a28ae5ee2 221 Gene3D G3DSA:1.10.150.750 19 92 1.3E-43 T 12-10-2018 VAPA_2c02630 884a6878149b49a66105066a28ae5ee2 221 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 104 182 2.4E-6 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 VAPA_1c36980 5f2946ad47e6355cb4b32d3569b14b41 275 Gene3D G3DSA:1.10.3210.10 1 270 2.8E-64 T 12-10-2018 VAPA_1c36980 5f2946ad47e6355cb4b32d3569b14b41 275 Pfam PF08668 HDOD domain 13 204 2.3E-53 T 12-10-2018 IPR013976 Metal-dependent hydrolase HDOD VAPA_1c36980 5f2946ad47e6355cb4b32d3569b14b41 275 SUPERFAMILY SSF109604 3 260 6.85E-60 T 12-10-2018 VAPA_1c02290 8223cc7de5cd6cc5e679fa225388886b 502 Pfam PF05943 Type VI secretion protein, EvpB/VC_A0108, tail sheath 71 495 1.9E-191 T 12-10-2018 IPR010269 Type VI secretion protein, EvpB/VC_A0108, tail sheath VAPA_1c02290 8223cc7de5cd6cc5e679fa225388886b 502 TIGRFAM TIGR03355 VI_chp_2: type VI secretion protein, EvpB/VC_A0108 family 22 495 1.2E-221 T 12-10-2018 IPR010269 Type VI secretion protein, EvpB/VC_A0108, tail sheath VAPA_1c03820 3c3796f52637e8714f95c13bd29ecb1a 503 Pfam PF01970 Tripartite tricarboxylate transporter TctA family 20 441 6.9E-150 T 12-10-2018 IPR002823 Protein of unknown function DUF112, transmembrane VAPA_1c31360 5faa2151ab02800ab38b6d0774838738 199 Pfam PF00696 Amino acid kinase family 2 141 7.4E-6 T 12-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 VAPA_1c31360 5faa2151ab02800ab38b6d0774838738 199 SUPERFAMILY SSF53633 1 141 1.31E-9 T 12-10-2018 IPR036393 Acetylglutamate kinase-like superfamily VAPA_1c31360 5faa2151ab02800ab38b6d0774838738 199 Gene3D G3DSA:3.40.1160.10 1 144 1.0E-16 T 12-10-2018 IPR036393 Acetylglutamate kinase-like superfamily VAPA_1c23450 a40241df62ba47eb016db795d9192ca6 376 Gene3D G3DSA:2.120.10.30 25 376 2.9E-114 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like VAPA_1c23450 a40241df62ba47eb016db795d9192ca6 376 Pfam PF07995 Glucose / Sorbosone dehydrogenase 40 372 2.9E-132 T 12-10-2018 IPR012938 Glucose/Sorbosone dehydrogenase VAPA_1c23450 a40241df62ba47eb016db795d9192ca6 376 SUPERFAMILY SSF50952 28 375 5.75E-44 T 12-10-2018 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 VAPA_1c47970 a461aa6d6a144b6af4fffe8a6b0a2f35 243 SUPERFAMILY SSF46626 127 216 4.28E-15 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 VAPA_1c47970 a461aa6d6a144b6af4fffe8a6b0a2f35 243 PIRSF PIRSF000005 2 220 1.5E-58 T 12-10-2018 IPR024167 Cytochrome c4-like GO:0005506|GO:0009055|GO:0020037|GO:0042597 VAPA_1c47970 a461aa6d6a144b6af4fffe8a6b0a2f35 243 Gene3D G3DSA:1.10.760.10 32 113 8.7E-18 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 VAPA_1c47970 a461aa6d6a144b6af4fffe8a6b0a2f35 243 Gene3D G3DSA:1.10.760.10 124 217 3.7E-16 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 VAPA_1c47970 a461aa6d6a144b6af4fffe8a6b0a2f35 243 SUPERFAMILY SSF46626 23 113 4.49E-17 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 VAPA_1c32350 de15edbac1240830f2c411c1f0d06d84 470 Pfam PF13546 DDE superfamily endonuclease 14 287 1.6E-94 T 12-10-2018 IPR038721 Transposase IS701-like, DDE domain VAPA_1c32350 de15edbac1240830f2c411c1f0d06d84 470 SUPERFAMILY SSF53098 17 397 4.17E-29 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily VAPA_1c45720 8789a21fd18b94ee6d96bb15fa320a8d 246 Gene3D G3DSA:3.40.50.360 12 184 1.3E-48 T 12-10-2018 IPR029039 Flavoprotein-like superfamily VAPA_1c45720 8789a21fd18b94ee6d96bb15fa320a8d 246 SUPERFAMILY SSF52218 14 184 1.42E-42 T 12-10-2018 IPR029039 Flavoprotein-like superfamily VAPA_1c45720 8789a21fd18b94ee6d96bb15fa320a8d 246 Pfam PF02525 Flavodoxin-like fold 14 179 6.9E-38 T 12-10-2018 IPR003680 Flavodoxin-like fold VAPA_1c42960 4e5b6797399be7f708c462b6b13bacfd 697 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 76 95 1.5E-55 T 12-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 VAPA_1c42960 4e5b6797399be7f708c462b6b13bacfd 697 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 192 209 1.5E-55 T 12-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 VAPA_1c42960 4e5b6797399be7f708c462b6b13bacfd 697 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 39 52 1.5E-55 T 12-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 VAPA_1c42960 4e5b6797399be7f708c462b6b13bacfd 697 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 143 159 1.5E-55 T 12-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 VAPA_1c42960 4e5b6797399be7f708c462b6b13bacfd 697 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 162 180 1.5E-55 T 12-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 VAPA_1c42960 4e5b6797399be7f708c462b6b13bacfd 697 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 243 257 1.5E-55 T 12-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 VAPA_1c42960 4e5b6797399be7f708c462b6b13bacfd 697 Gene3D G3DSA:3.40.30.60 365 508 2.1E-52 T 12-10-2018 VAPA_1c42960 4e5b6797399be7f708c462b6b13bacfd 697 Gene3D G3DSA:1.10.8.540 509 597 2.6E-26 T 12-10-2018 VAPA_1c42960 4e5b6797399be7f708c462b6b13bacfd 697 Pfam PF00771 FHIPEP family 32 684 1.3E-267 T 12-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 VAPA_1c42960 4e5b6797399be7f708c462b6b13bacfd 697 Gene3D G3DSA:1.10.490.80 600 693 4.6E-8 T 12-10-2018 VAPA_1c42960 4e5b6797399be7f708c462b6b13bacfd 697 TIGRFAM TIGR01398 FlhA: flagellar biosynthesis protein FlhA 23 693 6.6E-271 T 12-10-2018 IPR006301 Flagellar biosynthesis protein FlhA GO:0016021|GO:0044780 VAPA_1c42960 4e5b6797399be7f708c462b6b13bacfd 697 PIRSF PIRSF005419 7 696 6.1E-246 T 12-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 VAPA_1c14520 ddb5c89545bb529f2450dfeb33ea872c 492 SUPERFAMILY SSF48452 335 484 3.36E-6 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 VAPA_1c14520 ddb5c89545bb529f2450dfeb33ea872c 492 SUPERFAMILY SSF144091 13 295 1.44E-34 T 12-10-2018 VAPA_1c14520 ddb5c89545bb529f2450dfeb33ea872c 492 Gene3D G3DSA:1.20.1540.10 125 305 2.7E-26 T 12-10-2018 IPR035952 Rhomboid-like superfamily VAPA_1c14520 ddb5c89545bb529f2450dfeb33ea872c 492 Gene3D G3DSA:1.25.40.10 307 491 4.4E-7 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 VAPA_1c14520 ddb5c89545bb529f2450dfeb33ea872c 492 Pfam PF01694 Rhomboid family 148 295 4.2E-28 T 12-10-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 VAPA_1c50830 faa2b408d1b3eff7a7600202012413d0 165 Gene3D G3DSA:3.40.30.10 22 165 5.9E-38 T 12-10-2018 VAPA_1c50830 faa2b408d1b3eff7a7600202012413d0 165 SUPERFAMILY SSF52833 27 164 2.2E-37 T 12-10-2018 IPR036249 Thioredoxin-like superfamily VAPA_1c50830 faa2b408d1b3eff7a7600202012413d0 165 Pfam PF08534 Redoxin 28 149 6.4E-26 T 12-10-2018 IPR013740 Redoxin GO:0016491 Reactome: R-HSA-3299685|Reactome: R-HSA-5628897 VAPA_1c50310 76115406ee774507be1e67d8f11e5e76 211 PIRSF PIRSF000887 1 203 2.0E-49 T 12-10-2018 IPR024173 Phosphoesterase, MJ0037 VAPA_1c50310 76115406ee774507be1e67d8f11e5e76 211 SUPERFAMILY SSF56300 15 156 2.53E-16 T 12-10-2018 VAPA_1c50310 76115406ee774507be1e67d8f11e5e76 211 Gene3D G3DSA:3.60.21.10 15 121 1.5E-8 T 12-10-2018 IPR029052 Metallo-dependent phosphatase-like VAPA_1c50310 76115406ee774507be1e67d8f11e5e76 211 TIGRFAM TIGR04123 P_estr_lig_assc: metallophosphoesterase, DNA ligase-associated 1 202 2.6E-69 T 12-10-2018 IPR026336 Metallophosphoesterase, DNA ligase-associated VAPA_1c50310 76115406ee774507be1e67d8f11e5e76 211 Pfam PF00149 Calcineurin-like phosphoesterase 15 106 3.4E-6 T 12-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 VAPA_1c43920 8257d575d4ddc3c1a7f6e90ccc44a489 327 PIRSF PIRSF017082 1 327 9.4E-66 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c43920 8257d575d4ddc3c1a7f6e90ccc44a489 327 Gene3D G3DSA:3.40.190.150 30 317 8.0E-93 T 12-10-2018 VAPA_1c43920 8257d575d4ddc3c1a7f6e90ccc44a489 327 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 49 323 3.2E-65 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c43920 8257d575d4ddc3c1a7f6e90ccc44a489 327 Gene3D G3DSA:3.40.190.10 127 252 8.0E-93 T 12-10-2018 VAPA_1c27430 cb7c67a3eda6b46f4809f9928b668124 467 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 264 301 - T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 VAPA_1c27430 cb7c67a3eda6b46f4809f9928b668124 467 SUPERFAMILY SSF53383 23 446 3.48E-121 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase VAPA_1c27430 cb7c67a3eda6b46f4809f9928b668124 467 TIGRFAM TIGR00508 bioA: adenosylmethionine-8-amino-7-oxononanoate transaminase 27 444 3.2E-154 T 12-10-2018 IPR005815 Adenosylmethionine--8-amino-7-oxononanoate aminotransferase BioA GO:0004015|GO:0009102 KEGG: 00780+2.6.1.62 VAPA_1c27430 cb7c67a3eda6b46f4809f9928b668124 467 PIRSF PIRSF000521 42 449 5.3E-30 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 VAPA_1c27430 cb7c67a3eda6b46f4809f9928b668124 467 Gene3D G3DSA:3.90.1150.10 24 439 6.8E-146 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 VAPA_1c27430 cb7c67a3eda6b46f4809f9928b668124 467 Pfam PF00202 Aminotransferase class-III 42 441 1.5E-110 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 VAPA_1c27430 cb7c67a3eda6b46f4809f9928b668124 467 Gene3D G3DSA:3.40.640.10 77 353 6.8E-146 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 VAPA_1c47950 9ef866215171af4d36ec6678c8696522 484 Pfam PF00392 Bacterial regulatory proteins, gntR family 4 66 3.0E-13 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_1c47950 9ef866215171af4d36ec6678c8696522 484 Gene3D G3DSA:3.90.1150.10 100 467 3.0E-101 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 VAPA_1c47950 9ef866215171af4d36ec6678c8696522 484 SUPERFAMILY SSF46785 2 70 4.44E-16 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c47950 9ef866215171af4d36ec6678c8696522 484 SUPERFAMILY SSF53383 102 468 1.29E-92 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase VAPA_1c47950 9ef866215171af4d36ec6678c8696522 484 Gene3D G3DSA:1.10.10.10 1 67 2.1E-16 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c47950 9ef866215171af4d36ec6678c8696522 484 Gene3D G3DSA:3.40.640.10 144 362 3.0E-101 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 VAPA_1c47950 9ef866215171af4d36ec6678c8696522 484 Pfam PF00155 Aminotransferase class I and II 149 461 6.0E-30 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 VAPA_1c47950 9ef866215171af4d36ec6678c8696522 484 SMART SM00345 7 66 9.0E-14 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_1c05360 76ec4786e56d86b0fc3cf931dab69a33 315 SUPERFAMILY SSF63829 38 305 3.49E-59 T 12-10-2018 VAPA_1c05360 76ec4786e56d86b0fc3cf931dab69a33 315 Gene3D G3DSA:2.120.10.30 18 314 2.6E-69 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like VAPA_1c05360 76ec4786e56d86b0fc3cf931dab69a33 315 Pfam PF08450 SMP-30/Gluconolaconase/LRE-like region 47 285 2.5E-34 T 12-10-2018 IPR013658 SMP-30/Gluconolactonase/LRE-like region VAPA_1c36670 a859bfa268d331b9944b0801eddae9ae 456 Gene3D G3DSA:3.30.2290.10 11 238 6.2E-86 T 12-10-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal VAPA_1c36670 a859bfa268d331b9944b0801eddae9ae 456 Pfam PF01523 Putative modulator of DNA gyrase 43 329 2.1E-58 T 12-10-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 VAPA_1c36670 a859bfa268d331b9944b0801eddae9ae 456 SUPERFAMILY SSF111283 18 455 6.28E-124 T 12-10-2018 IPR036059 Metalloprotease TldD/PmbA superfamily GO:0006508|GO:0008237 VAPA_1c13940 9908afabe5598ac1ce77d99b505c4b8a 226 Pfam PF09601 Protein of unknown function (DUF2459) 50 214 2.7E-52 T 12-10-2018 IPR011727 Conserved hypothetical protein CHP02117 VAPA_1c13940 9908afabe5598ac1ce77d99b505c4b8a 226 TIGRFAM TIGR02117 chp_urease_rgn: conserved hypothetical protein 23 220 2.3E-47 T 12-10-2018 IPR011727 Conserved hypothetical protein CHP02117 VAPA_1c47900 e156a56177e296132182332e09e20658 259 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 100 120 - T 12-10-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824 VAPA_1c47900 e156a56177e296132182332e09e20658 259 Gene3D G3DSA:1.10.12.10 202 258 1.6E-25 T 12-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal VAPA_1c47900 e156a56177e296132182332e09e20658 259 Pfam PF00378 Enoyl-CoA hydratase/isomerase 14 258 1.1E-81 T 12-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 VAPA_1c47900 e156a56177e296132182332e09e20658 259 Gene3D G3DSA:3.90.226.10 1 200 3.7E-75 T 12-10-2018 VAPA_1c47900 e156a56177e296132182332e09e20658 259 SUPERFAMILY SSF52096 1 258 1.61E-89 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily VAPA_1c01760 bdeb71aa72078dd4fa53792845d6ea5a 268 SUPERFAMILY SSF56300 1 254 9.49E-29 T 12-10-2018 VAPA_1c01760 bdeb71aa72078dd4fa53792845d6ea5a 268 Gene3D G3DSA:3.60.21.10 1 259 8.3E-13 T 12-10-2018 IPR029052 Metallo-dependent phosphatase-like VAPA_1c01760 bdeb71aa72078dd4fa53792845d6ea5a 268 Pfam PF00149 Calcineurin-like phosphoesterase 18 233 5.1E-8 T 12-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 VAPA_1c18740 c00af79077c142ded5861e5b1ff79cc2 90 Pfam PF00216 Bacterial DNA-binding protein 1 90 6.4E-32 T 12-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 VAPA_1c18740 c00af79077c142ded5861e5b1ff79cc2 90 SUPERFAMILY SSF47729 1 90 1.3E-30 T 12-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 VAPA_1c18740 c00af79077c142ded5861e5b1ff79cc2 90 PRINTS PR01727 Prokaryotic integration host factor signature 40 55 1.4E-18 T 12-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 VAPA_1c18740 c00af79077c142ded5861e5b1ff79cc2 90 PRINTS PR01727 Prokaryotic integration host factor signature 58 71 1.4E-18 T 12-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 VAPA_1c18740 c00af79077c142ded5861e5b1ff79cc2 90 PRINTS PR01727 Prokaryotic integration host factor signature 74 88 1.4E-18 T 12-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 VAPA_1c18740 c00af79077c142ded5861e5b1ff79cc2 90 SMART SM00411 1 90 2.4E-36 T 12-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 VAPA_1c18740 c00af79077c142ded5861e5b1ff79cc2 90 Gene3D G3DSA:4.10.520.10 1 90 8.9E-34 T 12-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 VAPA_1c18740 c00af79077c142ded5861e5b1ff79cc2 90 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 46 65 - T 12-10-2018 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 VAPA_1c06350 c641106dab1a67a8e508bf834ab12640 186 Pfam PF00583 Acetyltransferase (GNAT) family 61 145 1.9E-8 T 12-10-2018 IPR000182 GNAT domain VAPA_1c06350 c641106dab1a67a8e508bf834ab12640 186 SUPERFAMILY SSF55729 18 165 1.51E-28 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase VAPA_1c06350 c641106dab1a67a8e508bf834ab12640 186 Gene3D G3DSA:3.40.630.30 18 166 5.6E-24 T 12-10-2018 VAPA_1c06350 c641106dab1a67a8e508bf834ab12640 186 TIGRFAM TIGR04045 MSMEG_0567_GNAT: putative N-acetyltransferase, MSMEG_0567 N-terminal domain family 18 171 5.9E-70 T 12-10-2018 IPR024035 GNAT N-acetyltransferase, putative VAPA_1c31020 8e4272d6ce438ef777fe2c906293e8ea 276 PRINTS PR00164 ABC-2 type transport system membrane protein signature 158 182 9.3E-5 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 VAPA_1c31020 8e4272d6ce438ef777fe2c906293e8ea 276 PRINTS PR00164 ABC-2 type transport system membrane protein signature 39 60 9.3E-5 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 VAPA_1c31020 8e4272d6ce438ef777fe2c906293e8ea 276 PRINTS PR00164 ABC-2 type transport system membrane protein signature 195 214 9.3E-5 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 VAPA_1c31020 8e4272d6ce438ef777fe2c906293e8ea 276 PIRSF PIRSF006648 3 269 1.0E-38 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 VAPA_1c31020 8e4272d6ce438ef777fe2c906293e8ea 276 TIGRFAM TIGR03861 phenyl_ABC_PedC: alcohol ABC transporter, permease protein 18 255 3.4E-104 T 12-10-2018 IPR022403 Alcohol ABC transporter, permease protein VAPA_1c31020 8e4272d6ce438ef777fe2c906293e8ea 276 Pfam PF01061 ABC-2 type transporter 21 242 4.7E-30 T 12-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 VAPA_1c18230 18b418e97e24108ee56b551221cbc091 350 SUPERFAMILY SSF53067 159 317 1.59E-18 T 12-10-2018 VAPA_1c18230 18b418e97e24108ee56b551221cbc091 350 Gene3D G3DSA:3.30.420.40 184 346 7.3E-16 T 12-10-2018 VAPA_2c10920 31d9984cf4748902b72179ff01c8cb88 161 Pfam PF14588 YjgF/chorismate_mutase-like, putative endoribonuclease 8 154 2.1E-16 T 12-10-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like VAPA_2c10920 31d9984cf4748902b72179ff01c8cb88 161 SUPERFAMILY SSF55298 5 158 9.42E-37 T 12-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 VAPA_2c10920 31d9984cf4748902b72179ff01c8cb88 161 Gene3D G3DSA:3.30.1330.40 2 157 6.2E-45 T 12-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 VAPA_1c15170 113928a16caa17a95b8026bfb5883e8f 46 Pfam PF08085 Entericidin EcnA/B family 22 42 5.4E-11 T 12-10-2018 IPR012556 Entericidin A/B GO:0009636|GO:0016020 VAPA_1c29470 ed91c8091e6fae02e7f7363b52269c5e 395 TIGRFAM TIGR00243 Dxr: 1-deoxy-D-xylulose 5-phosphate reductoisomerase 6 389 8.4E-143 T 12-10-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 VAPA_1c29470 ed91c8091e6fae02e7f7363b52269c5e 395 Pfam PF13288 DXP reductoisomerase C-terminal domain 268 384 3.1E-36 T 12-10-2018 IPR026877 DXP reductoisomerase C-terminal domain KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 VAPA_1c29470 ed91c8091e6fae02e7f7363b52269c5e 395 SUPERFAMILY SSF69055 299 388 1.57E-24 T 12-10-2018 IPR036169 DXP reductoisomerase, C-terminal domain superfamily KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 VAPA_1c29470 ed91c8091e6fae02e7f7363b52269c5e 395 SUPERFAMILY SSF55347 130 271 6.87E-59 T 12-10-2018 VAPA_1c29470 ed91c8091e6fae02e7f7363b52269c5e 395 Gene3D G3DSA:3.40.50.720 1 154 6.2E-52 T 12-10-2018 VAPA_1c29470 ed91c8091e6fae02e7f7363b52269c5e 395 Pfam PF02670 1-deoxy-D-xylulose 5-phosphate reductoisomerase 8 136 3.4E-45 T 12-10-2018 IPR013512 1-deoxy-D-xylulose 5-phosphate reductoisomerase, N-terminal GO:0055114|GO:0070402 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 VAPA_1c29470 ed91c8091e6fae02e7f7363b52269c5e 395 Hamap MF_00183 1-deoxy-D-xylulose 5-phosphate reductoisomerase [dxr]. 8 389 44.668 T 12-10-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 VAPA_1c29470 ed91c8091e6fae02e7f7363b52269c5e 395 PIRSF PIRSF006205 5 394 2.1E-145 T 12-10-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 VAPA_1c29470 ed91c8091e6fae02e7f7363b52269c5e 395 Gene3D G3DSA:1.10.1740.10 310 392 2.6E-22 T 12-10-2018 VAPA_1c29470 ed91c8091e6fae02e7f7363b52269c5e 395 SUPERFAMILY SSF51735 6 154 2.01E-43 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c29470 ed91c8091e6fae02e7f7363b52269c5e 395 Pfam PF08436 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal 150 236 6.3E-37 T 12-10-2018 IPR013644 1-deoxy-D-xylulose 5-phosphate reductoisomerase, C-terminal GO:0005515 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 VAPA_1c18140 d89f51c7bc3da6f0add7ae2ac053f6cd 274 SUPERFAMILY SSF51735 13 247 8.96E-38 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c18140 d89f51c7bc3da6f0add7ae2ac053f6cd 274 Gene3D G3DSA:3.40.50.720 13 238 1.8E-58 T 12-10-2018 VAPA_1c18140 d89f51c7bc3da6f0add7ae2ac053f6cd 274 Pfam PF01370 NAD dependent epimerase/dehydratase family 15 174 2.3E-17 T 12-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 VAPA_2c12280 f7258b8f0276404bc932cc8ce9785ba3 101 Gene3D G3DSA:1.10.260.40 1 85 5.6E-15 T 12-10-2018 VAPA_2c12280 f7258b8f0276404bc932cc8ce9785ba3 101 Pfam PF13560 Helix-turn-helix domain 10 65 4.5E-11 T 12-10-2018 VAPA_2c12280 f7258b8f0276404bc932cc8ce9785ba3 101 SUPERFAMILY SSF47413 5 66 1.05E-16 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 VAPA_2c12280 f7258b8f0276404bc932cc8ce9785ba3 101 SMART SM00530 14 69 4.6E-9 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 VAPA_1c07440 18056e1a29f2f680440ca51aebba79c5 200 SUPERFAMILY SSF140478 162 196 1.44E-5 T 12-10-2018 IPR023353 LemA-like domain superfamily VAPA_1c07440 18056e1a29f2f680440ca51aebba79c5 200 Pfam PF04011 LemA family 12 58 5.8E-5 T 12-10-2018 IPR007156 LemA VAPA_1c41120 ca9894b97c207c05d0270f7a207ea583 110 Pfam PF01638 HxlR-like helix-turn-helix 17 105 1.1E-33 T 12-10-2018 IPR002577 Helix-turn-helix, HxlR type VAPA_1c41120 ca9894b97c207c05d0270f7a207ea583 110 SUPERFAMILY SSF46785 5 105 6.49E-30 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c41120 ca9894b97c207c05d0270f7a207ea583 110 Gene3D G3DSA:1.10.10.10 2 110 1.1E-37 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c22560 85a9a277a4ca804af3322fc7ecf2fee9 264 Pfam PF00106 short chain dehydrogenase 3 188 1.4E-42 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c22560 85a9a277a4ca804af3322fc7ecf2fee9 264 SUPERFAMILY SSF51735 3 248 1.66E-56 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c22560 85a9a277a4ca804af3322fc7ecf2fee9 264 Gene3D G3DSA:3.40.50.720 2 254 4.7E-61 T 12-10-2018 VAPA_1c22560 85a9a277a4ca804af3322fc7ecf2fee9 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 3.3E-25 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c22560 85a9a277a4ca804af3322fc7ecf2fee9 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 3.3E-25 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c22560 85a9a277a4ca804af3322fc7ecf2fee9 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 3.3E-25 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c22560 85a9a277a4ca804af3322fc7ecf2fee9 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 216 236 3.3E-25 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c22560 85a9a277a4ca804af3322fc7ecf2fee9 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 3.3E-25 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c22560 85a9a277a4ca804af3322fc7ecf2fee9 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 3.3E-25 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c22560 85a9a277a4ca804af3322fc7ecf2fee9 264 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 156 175 5.3E-7 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c22560 85a9a277a4ca804af3322fc7ecf2fee9 264 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 5.3E-7 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c22560 85a9a277a4ca804af3322fc7ecf2fee9 264 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 137 145 5.3E-7 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c52870 2486d39f485ae82964bfb820426e4853 301 SUPERFAMILY SSF56104 4 301 1.28E-101 T 12-10-2018 VAPA_1c52870 2486d39f485ae82964bfb820426e4853 301 ProSitePatterns PS01057 SAICAR synthetase signature 1. 105 119 - T 12-10-2018 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 VAPA_1c52870 2486d39f485ae82964bfb820426e4853 301 TIGRFAM TIGR00081 purC: phosphoribosylaminoimidazolesuccinocarboxamide synthase 10 300 3.8E-74 T 12-10-2018 IPR001636 Phosphoribosylaminoimidazole-succinocarboxamide synthase GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234 VAPA_1c52870 2486d39f485ae82964bfb820426e4853 301 Gene3D G3DSA:3.30.200.20 2 103 2.7E-31 T 12-10-2018 VAPA_1c52870 2486d39f485ae82964bfb820426e4853 301 ProSitePatterns PS01058 SAICAR synthetase signature 2. 204 212 - T 12-10-2018 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 VAPA_1c52870 2486d39f485ae82964bfb820426e4853 301 Pfam PF01259 SAICAR synthetase 15 266 1.5E-100 T 12-10-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 VAPA_1c52870 2486d39f485ae82964bfb820426e4853 301 Gene3D G3DSA:3.30.470.20 105 246 2.8E-59 T 12-10-2018 VAPA_1c52870 2486d39f485ae82964bfb820426e4853 301 Hamap MF_00137 Phosphoribosylaminoimidazole-succinocarboxamide synthase [purC]. 12 301 26.068 T 12-10-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 VAPA_1c06940 554f80da3f594fdb9cee843de301a1fb 416 SUPERFAMILY SSF53187 26 402 2.39E-14 T 12-10-2018 VAPA_1c06940 554f80da3f594fdb9cee843de301a1fb 416 Gene3D G3DSA:3.40.630.10 189 411 3.6E-5 T 12-10-2018 VAPA_1c17280 4f9e72cd47e96388eeb6c99587302b07 91 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 9 60 7.1E-11 T 12-10-2018 VAPA_1c17280 4f9e72cd47e96388eeb6c99587302b07 91 Gene3D G3DSA:3.40.1620.40 9 66 2.4E-6 T 12-10-2018 VAPA_1c17280 4f9e72cd47e96388eeb6c99587302b07 91 SUPERFAMILY SSF143120 6 78 1.57E-16 T 12-10-2018 IPR036165 YefM-like superfamily VAPA_1c17280 4f9e72cd47e96388eeb6c99587302b07 91 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 6 72 2.6E-17 T 12-10-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM VAPA_1c38950 f90cae6190d6f130d563722e589e6a0d 108 Hamap MF_01537 Pyrimidine/purine nucleoside phosphorylase [ppnP]. 14 108 26.218 T 12-10-2018 IPR009664 Pyrimidine/purine nucleoside phosphorylase KEGG: 00230+2.4.2.15|KEGG: 00240+2.4.2.4+2.4.2.3+2.4.2.2|KEGG: 00983+2.4.2.4+2.4.2.3|MetaCyc: PWY-5532|MetaCyc: PWY-7181 VAPA_1c38950 f90cae6190d6f130d563722e589e6a0d 108 Gene3D G3DSA:2.60.120.10 1 108 5.5E-38 T 12-10-2018 IPR014710 RmlC-like jelly roll fold VAPA_1c38950 f90cae6190d6f130d563722e589e6a0d 108 Pfam PF06865 Protein of unknown function (DUF1255) 16 107 3.4E-34 T 12-10-2018 IPR009664 Pyrimidine/purine nucleoside phosphorylase KEGG: 00230+2.4.2.15|KEGG: 00240+2.4.2.4+2.4.2.3+2.4.2.2|KEGG: 00983+2.4.2.4+2.4.2.3|MetaCyc: PWY-5532|MetaCyc: PWY-7181 VAPA_1c38950 f90cae6190d6f130d563722e589e6a0d 108 SUPERFAMILY SSF51182 15 107 2.67E-30 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily VAPA_1c08330 44d0f913d62d542747a7a4d992733022 252 Gene3D G3DSA:3.90.550.10 7 225 7.3E-24 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases VAPA_1c08330 44d0f913d62d542747a7a4d992733022 252 SUPERFAMILY SSF53448 12 231 4.5E-31 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases VAPA_1c08330 44d0f913d62d542747a7a4d992733022 252 Pfam PF13641 Glycosyltransferase like family 2 67 217 5.4E-9 T 12-10-2018 VAPA_2c07010 3b11749daca0943b9d644a98d2b56af2 597 Pfam PF00005 ABC transporter 351 510 1.5E-28 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_2c07010 3b11749daca0943b9d644a98d2b56af2 597 SMART SM00382 359 558 3.3E-8 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_2c07010 3b11749daca0943b9d644a98d2b56af2 597 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 560 581 3.6E-11 T 12-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal VAPA_2c07010 3b11749daca0943b9d644a98d2b56af2 597 Gene3D G3DSA:3.40.50.300 331 583 6.1E-58 T 12-10-2018 VAPA_2c07010 3b11749daca0943b9d644a98d2b56af2 597 SUPERFAMILY SSF52540 334 581 1.78E-61 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_2c07010 3b11749daca0943b9d644a98d2b56af2 597 Pfam PF02653 Branched-chain amino acid transport system / permease component 30 292 5.2E-37 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 VAPA_1c40900 da6b05c478d3dde60046b39aa95058ff 143 Pfam PF09912 Uncharacterized protein conserved in bacteria (DUF2141) 38 137 6.9E-30 T 12-10-2018 IPR018673 Protein of unknown function DUF2141 VAPA_1c23420 875a642f33999a2d45581559d8beaaca 197 Gene3D G3DSA:3.60.20.10 2 192 1.1E-32 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal VAPA_1c23420 875a642f33999a2d45581559d8beaaca 197 SUPERFAMILY SSF56235 1 191 5.23E-27 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal VAPA_1c23420 875a642f33999a2d45581559d8beaaca 197 Pfam PF00227 Proteasome subunit 2 183 3.6E-9 T 12-10-2018 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 VAPA_1c38460 8da66bd60160a2708d58b7c7cb87e385 225 SUPERFAMILY SSF53335 7 183 9.51E-41 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase VAPA_1c38460 8da66bd60160a2708d58b7c7cb87e385 225 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 15 197 1.9E-27 T 12-10-2018 VAPA_1c38460 8da66bd60160a2708d58b7c7cb87e385 225 Gene3D G3DSA:3.40.50.150 8 206 7.8E-45 T 12-10-2018 VAPA_1c46100 acd728cfc29ff4b190b1f5635bde0259 213 Gene3D G3DSA:3.40.1080.10 4 213 2.4E-80 T 12-10-2018 VAPA_1c46100 acd728cfc29ff4b190b1f5635bde0259 213 TIGRFAM TIGR02428 pcaJ_scoB_fam: 3-oxoacid CoA-transferase, B subunit 7 206 5.5E-86 T 12-10-2018 IPR012791 3-oxoacid CoA-transferase, subunit B GO:0008410 Reactome: R-HSA-77108 VAPA_1c46100 acd728cfc29ff4b190b1f5635bde0259 213 SUPERFAMILY SSF100950 7 211 6.09E-62 T 12-10-2018 IPR037171 NagB/RpiA transferase-like VAPA_1c46100 acd728cfc29ff4b190b1f5635bde0259 213 SMART SM00882 9 206 8.5E-65 T 12-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 VAPA_1c46100 acd728cfc29ff4b190b1f5635bde0259 213 ProSitePatterns PS01274 Coenzyme A transferases signature 2. 47 55 - T 12-10-2018 IPR004164 Coenzyme A transferase active site GO:0008410 Reactome: R-HSA-77108 VAPA_1c46100 acd728cfc29ff4b190b1f5635bde0259 213 Pfam PF01144 Coenzyme A transferase 9 192 4.8E-35 T 12-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 VAPA_1c44030 b263673598c8b78650237dda42bce64b 134 Gene3D G3DSA:1.20.120.1870 9 133 7.6E-42 T 12-10-2018 VAPA_1c44030 b263673598c8b78650237dda42bce64b 134 TIGRFAM TIGR01550 DOC_P1: death-on-curing family protein 28 126 1.4E-18 T 12-10-2018 IPR006440 Death on curing protein GO:0016301 VAPA_1c44030 b263673598c8b78650237dda42bce64b 134 Pfam PF02661 Fic/DOC family 10 90 2.8E-14 T 12-10-2018 IPR003812 Fido domain VAPA_1c44030 b263673598c8b78650237dda42bce64b 134 SUPERFAMILY SSF140931 10 96 2.88E-8 T 12-10-2018 IPR036597 Fido-like domain superfamily VAPA_1c44030 b263673598c8b78650237dda42bce64b 134 PIRSF PIRSF018297 7 133 3.2E-44 T 12-10-2018 IPR006440 Death on curing protein GO:0016301 VAPA_1c27280 ed0677eaea10f1401e4075bb351fc3a0 470 SUPERFAMILY SSF102114 19 458 8.76E-130 T 12-10-2018 VAPA_1c27280 ed0677eaea10f1401e4075bb351fc3a0 470 Pfam PF04055 Radical SAM superfamily 71 242 1.2E-18 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 VAPA_1c27280 ed0677eaea10f1401e4075bb351fc3a0 470 TIGRFAM TIGR00538 hemN: oxygen-independent coproporphyrinogen III oxidase 18 470 1.6E-167 T 12-10-2018 IPR004558 Oxygen-independent coproporphyrinogen III oxidase HemN GO:0004109|GO:0005737|GO:0006779|GO:0055114 KEGG: 00860+1.3.98.3|MetaCyc: PWY-5531 VAPA_1c27280 ed0677eaea10f1401e4075bb351fc3a0 470 Pfam PF06969 HemN C-terminal domain 378 446 1.4E-6 T 12-10-2018 IPR010723 HemN, C-terminal VAPA_1c27280 ed0677eaea10f1401e4075bb351fc3a0 470 Gene3D G3DSA:1.10.10.920 379 470 7.7E-29 T 12-10-2018 VAPA_1c27280 ed0677eaea10f1401e4075bb351fc3a0 470 PIRSF PIRSF000167 17 470 3.2E-160 T 12-10-2018 IPR004558 Oxygen-independent coproporphyrinogen III oxidase HemN GO:0004109|GO:0005737|GO:0006779|GO:0055114 KEGG: 00860+1.3.98.3|MetaCyc: PWY-5531 VAPA_1c27280 ed0677eaea10f1401e4075bb351fc3a0 470 Gene3D G3DSA:3.80.30.20 15 378 7.6E-120 T 12-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe VAPA_1c27280 ed0677eaea10f1401e4075bb351fc3a0 470 SMART SM00729 66 284 1.3E-45 T 12-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 VAPA_1c34000 4d1e99b9ed586378e60134742fde2171 430 SUPERFAMILY SSF103473 24 428 8.37E-80 T 12-10-2018 IPR036259 MFS transporter superfamily VAPA_1c34000 4d1e99b9ed586378e60134742fde2171 430 Pfam PF07690 Major Facilitator Superfamily 36 297 2.1E-29 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 VAPA_1c34000 4d1e99b9ed586378e60134742fde2171 430 Gene3D G3DSA:1.20.1250.20 29 430 7.1E-75 T 12-10-2018 VAPA_1c34000 4d1e99b9ed586378e60134742fde2171 430 ProSitePatterns PS00216 Sugar transport proteins signature 1. 296 313 - T 12-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 VAPA_1c34000 4d1e99b9ed586378e60134742fde2171 430 ProSitePatterns PS00217 Sugar transport proteins signature 2. 127 152 - T 12-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 VAPA_1c12390 29c796a84c19c5bc32904e5c5212b197 82 TIGRFAM TIGR01411 tatAE: twin arginine-targeting protein translocase, TatA/E family 3 47 1.7E-22 T 12-10-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 VAPA_1c12390 29c796a84c19c5bc32904e5c5212b197 82 Pfam PF02416 mttA/Hcf106 family 5 48 1.3E-12 T 12-10-2018 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 VAPA_1c12390 29c796a84c19c5bc32904e5c5212b197 82 Hamap MF_00236 Sec-independent protein translocase protein TatA [tatA]. 1 82 23.367 T 12-10-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 VAPA_1c14610 7b4f1c95e6c166eefdcfa64c70b4ae97 313 Gene3D G3DSA:3.40.190.10 175 276 4.0E-43 T 12-10-2018 VAPA_1c14610 7b4f1c95e6c166eefdcfa64c70b4ae97 313 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 14 72 5.4E-20 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c14610 7b4f1c95e6c166eefdcfa64c70b4ae97 313 Pfam PF03466 LysR substrate binding domain 98 301 1.2E-47 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_1c14610 7b4f1c95e6c166eefdcfa64c70b4ae97 313 SUPERFAMILY SSF46785 11 122 7.79E-25 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c14610 7b4f1c95e6c166eefdcfa64c70b4ae97 313 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 40 3.4E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c14610 7b4f1c95e6c166eefdcfa64c70b4ae97 313 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 50 3.4E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c14610 7b4f1c95e6c166eefdcfa64c70b4ae97 313 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 50 61 3.4E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c14610 7b4f1c95e6c166eefdcfa64c70b4ae97 313 SUPERFAMILY SSF53850 99 305 9.88E-44 T 12-10-2018 VAPA_1c14610 7b4f1c95e6c166eefdcfa64c70b4ae97 313 Gene3D G3DSA:1.10.10.10 8 94 8.8E-24 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c14610 7b4f1c95e6c166eefdcfa64c70b4ae97 313 Gene3D G3DSA:3.40.190.10 102 290 4.0E-43 T 12-10-2018 VAPA_1c40280 97f70b9690fde8b04bd7ca3c2489b4a2 69 SUPERFAMILY SSF160582 1 65 7.19E-28 T 12-10-2018 IPR038020 MbtH-like domain superfamily VAPA_1c40280 97f70b9690fde8b04bd7ca3c2489b4a2 69 Pfam PF03621 MbtH-like protein 1 52 4.4E-27 T 12-10-2018 IPR005153 MbtH-like domain VAPA_1c40280 97f70b9690fde8b04bd7ca3c2489b4a2 69 Gene3D G3DSA:3.90.820.10 1 67 7.4E-32 T 12-10-2018 VAPA_1c40280 97f70b9690fde8b04bd7ca3c2489b4a2 69 SMART SM00923 3 53 7.1E-28 T 12-10-2018 IPR005153 MbtH-like domain VAPA_1c50850 d4e01823057f2ffa268999d762533d79 168 Pfam PF08534 Redoxin 3 163 7.7E-37 T 12-10-2018 IPR013740 Redoxin GO:0016491 Reactome: R-HSA-3299685|Reactome: R-HSA-5628897 VAPA_1c50850 d4e01823057f2ffa268999d762533d79 168 SUPERFAMILY SSF52833 1 164 2.41E-35 T 12-10-2018 IPR036249 Thioredoxin-like superfamily VAPA_1c50850 d4e01823057f2ffa268999d762533d79 168 Gene3D G3DSA:3.40.30.10 1 166 4.2E-61 T 12-10-2018 VAPA_1c48520 3c2a678882f240d7a5d423c74f12677a 414 Gene3D G3DSA:1.10.3720.10 172 411 6.5E-49 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c48520 3c2a678882f240d7a5d423c74f12677a 414 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 226 407 9.0E-12 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 VAPA_1c48520 3c2a678882f240d7a5d423c74f12677a 414 SUPERFAMILY SSF161098 191 403 1.09E-46 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c06890 21eceb741a75bbb24afa73ba7731fc4f 342 Pfam PF02653 Branched-chain amino acid transport system / permease component 38 297 2.4E-33 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 VAPA_1c49790 983a6a2f273423843a2684da31c6d656 228 Gene3D G3DSA:3.20.20.10 1 228 1.8E-81 T 12-10-2018 IPR029066 PLP-binding barrel VAPA_1c49790 983a6a2f273423843a2684da31c6d656 228 PIRSF PIRSF004848 1 228 2.0E-67 T 12-10-2018 IPR011078 Pyridoxal phosphate homeostasis protein GO:0030170 VAPA_1c49790 983a6a2f273423843a2684da31c6d656 228 Pfam PF01168 Alanine racemase, N-terminal domain 7 227 3.0E-33 T 12-10-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 VAPA_1c49790 983a6a2f273423843a2684da31c6d656 228 SUPERFAMILY SSF51419 4 226 1.27E-77 T 12-10-2018 IPR029066 PLP-binding barrel VAPA_1c49790 983a6a2f273423843a2684da31c6d656 228 Hamap MF_02087 Pyridoxal phosphate homeostasis protein. 6 227 31.075 T 12-10-2018 IPR011078 Pyridoxal phosphate homeostasis protein GO:0030170 VAPA_1c49790 983a6a2f273423843a2684da31c6d656 228 TIGRFAM TIGR00044 TIGR00044: pyridoxal phosphate enzyme, YggS family 2 228 4.3E-75 T 12-10-2018 IPR011078 Pyridoxal phosphate homeostasis protein GO:0030170 VAPA_1c34220 18332557eedd91b2f3daf71b31476445 630 SUPERFAMILY SSF51658 2 269 1.66E-67 T 12-10-2018 IPR036237 Xylose isomerase-like superfamily VAPA_1c34220 18332557eedd91b2f3daf71b31476445 630 SUPERFAMILY SSF54593 288 626 3.95E-53 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase VAPA_1c34220 18332557eedd91b2f3daf71b31476445 630 Gene3D G3DSA:3.20.20.150 1 273 2.4E-64 T 12-10-2018 VAPA_1c34220 18332557eedd91b2f3daf71b31476445 630 Gene3D G3DSA:3.10.180.10 293 441 1.3E-35 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase VAPA_1c34220 18332557eedd91b2f3daf71b31476445 630 Pfam PF14696 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal 296 429 1.7E-31 T 12-10-2018 VAPA_1c34220 18332557eedd91b2f3daf71b31476445 630 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 447 568 7.2E-7 T 12-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain VAPA_1c34220 18332557eedd91b2f3daf71b31476445 630 Pfam PF01261 Xylose isomerase-like TIM barrel 18 218 8.1E-34 T 12-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain VAPA_1c34220 18332557eedd91b2f3daf71b31476445 630 Gene3D G3DSA:3.10.180.10 442 630 1.1E-37 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase VAPA_1c50300 eec07eee5fe8d672aae3927dc45cfb4b 174 Gene3D G3DSA:3.10.310.50 21 171 2.0E-46 T 12-10-2018 VAPA_1c50300 eec07eee5fe8d672aae3927dc45cfb4b 174 Pfam PF04536 TPM domain 28 148 3.7E-11 T 12-10-2018 IPR007621 TPM domain VAPA_1c33840 303608582412162317308ec97d745811 473 Gene3D G3DSA:1.20.1740.10 19 469 7.6E-53 T 12-10-2018 VAPA_1c33840 303608582412162317308ec97d745811 473 Pfam PF13520 Amino acid permease 24 432 4.1E-39 T 12-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 VAPA_1c33840 303608582412162317308ec97d745811 473 PIRSF PIRSF006060 8 468 6.3E-66 T 12-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 VAPA_1c33840 303608582412162317308ec97d745811 473 TIGRFAM TIGR00908 2A0305: ethanolamine permease 19 465 6.0E-183 T 12-10-2018 IPR004757 Ethanolamine permease VAPA_2c02600 22fec350ce17bc63c7a6dc713d97cdae 318 Gene3D G3DSA:1.10.3720.10 90 307 6.4E-24 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_2c02600 22fec350ce17bc63c7a6dc713d97cdae 318 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 118 316 5.1E-29 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 VAPA_2c02600 22fec350ce17bc63c7a6dc713d97cdae 318 SUPERFAMILY SSF161098 96 299 1.7E-19 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c27730 d61feb8607a7d10dd56029e7b8c6f50b 251 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_1c27730 d61feb8607a7d10dd56029e7b8c6f50b 251 SMART SM00382 34 216 1.5E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c27730 d61feb8607a7d10dd56029e7b8c6f50b 251 Gene3D G3DSA:3.40.50.300 5 247 1.9E-55 T 12-10-2018 VAPA_1c27730 d61feb8607a7d10dd56029e7b8c6f50b 251 SUPERFAMILY SSF52540 6 237 1.28E-50 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c27730 d61feb8607a7d10dd56029e7b8c6f50b 251 Pfam PF00005 ABC transporter 26 167 3.0E-24 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c52810 5ee81c91b7a3e67a318d71a7d0daf880 527 SUPERFAMILY SSF53474 108 458 1.76E-22 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c52810 5ee81c91b7a3e67a318d71a7d0daf880 527 Pfam PF00326 Prolyl oligopeptidase family 165 258 3.7E-8 T 12-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 VAPA_1c52810 5ee81c91b7a3e67a318d71a7d0daf880 527 Gene3D G3DSA:3.40.50.1820 382 487 1.8E-8 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c52810 5ee81c91b7a3e67a318d71a7d0daf880 527 Gene3D G3DSA:3.40.50.1820 49 277 2.0E-45 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c03590 e2343d823072a5cfe7f11829abbb615c 172 SUPERFAMILY SSF51316 11 155 3.35E-41 T 12-10-2018 IPR011057 Mss4-like superfamily VAPA_1c03590 e2343d823072a5cfe7f11829abbb615c 172 Gene3D G3DSA:3.90.1590.10 5 135 2.1E-14 T 12-10-2018 VAPA_1c03590 e2343d823072a5cfe7f11829abbb615c 172 Pfam PF04828 Glutathione-dependent formaldehyde-activating enzyme 35 126 5.0E-22 T 12-10-2018 IPR006913 Glutathione-dependent formaldehyde-activating enzyme/centromere protein V GO:0016846 KEGG: 00680+4.4.1.22|MetaCyc: PWY-1801 VAPA_1c08070 0c9cd954f71d57afe9a7e73bbc484ea2 409 Gene3D G3DSA:3.40.640.10 64 286 1.1E-134 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 VAPA_1c08070 0c9cd954f71d57afe9a7e73bbc484ea2 409 Gene3D G3DSA:3.90.1150.10 15 389 1.1E-134 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 VAPA_1c08070 0c9cd954f71d57afe9a7e73bbc484ea2 409 SUPERFAMILY SSF53383 2 393 7.54E-100 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase VAPA_1c08070 0c9cd954f71d57afe9a7e73bbc484ea2 409 Pfam PF00155 Aminotransferase class I and II 42 388 1.6E-31 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 VAPA_1c46760 26d2bb74e800e634952e99f3f2307f8d 108 Gene3D G3DSA:3.30.2310.20 3 107 6.1E-10 T 12-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily VAPA_1c46760 26d2bb74e800e634952e99f3f2307f8d 108 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 7 105 5.6E-12 T 12-10-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family VAPA_2c05220 fdea1a4a99ec91e5cdc96f0e8cc01946 256 Gene3D G3DSA:1.10.3720.10 54 250 6.6E-27 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_2c05220 fdea1a4a99ec91e5cdc96f0e8cc01946 256 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 80 248 3.9E-24 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 VAPA_2c05220 fdea1a4a99ec91e5cdc96f0e8cc01946 256 SUPERFAMILY SSF161098 55 242 1.57E-32 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c40590 0b7b58186b9c3b975c4aa830c846559e 345 Gene3D G3DSA:3.40.190.170 28 343 1.1E-99 T 12-10-2018 IPR038404 TRAP transporter solute receptor DctP superfamily VAPA_1c40590 0b7b58186b9c3b975c4aa830c846559e 345 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 37 316 8.9E-86 T 12-10-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0030288|GO:0055085 VAPA_1c40590 0b7b58186b9c3b975c4aa830c846559e 345 PIRSF PIRSF006470 1 334 1.3E-105 T 12-10-2018 IPR004682 TRAP transporter solute receptor, DctP family GO:0030288|GO:0055085 VAPA_1c40590 0b7b58186b9c3b975c4aa830c846559e 345 TIGRFAM TIGR00787 dctP: TRAP transporter solute receptor, DctP family 38 290 9.8E-78 T 12-10-2018 IPR004682 TRAP transporter solute receptor, DctP family GO:0030288|GO:0055085 VAPA_1c08550 d999dc450c318052827948275576a5e2 327 Pfam PF02653 Branched-chain amino acid transport system / permease component 31 300 2.1E-40 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 VAPA_2c08420 ecb094b4d12c0c97e9473e1ddd07f624 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 152 171 1.5E-5 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c08420 ecb094b4d12c0c97e9473e1ddd07f624 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 132 140 1.5E-5 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c08420 ecb094b4d12c0c97e9473e1ddd07f624 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 80 91 1.5E-5 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c08420 ecb094b4d12c0c97e9473e1ddd07f624 263 Gene3D G3DSA:3.40.50.720 2 255 5.5E-72 T 12-10-2018 VAPA_2c08420 ecb094b4d12c0c97e9473e1ddd07f624 263 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 139 167 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 VAPA_2c08420 ecb094b4d12c0c97e9473e1ddd07f624 263 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 19 247 1.4E-58 T 12-10-2018 VAPA_2c08420 ecb094b4d12c0c97e9473e1ddd07f624 263 SUPERFAMILY SSF51735 6 250 4.48E-71 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_2c08420 ecb094b4d12c0c97e9473e1ddd07f624 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 2.8E-30 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c08420 ecb094b4d12c0c97e9473e1ddd07f624 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 126 142 2.8E-30 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c08420 ecb094b4d12c0c97e9473e1ddd07f624 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 2.8E-30 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c08420 ecb094b4d12c0c97e9473e1ddd07f624 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 152 171 2.8E-30 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c08420 ecb094b4d12c0c97e9473e1ddd07f624 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 210 230 2.8E-30 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c08420 ecb094b4d12c0c97e9473e1ddd07f624 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 173 190 2.8E-30 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c06300 2ae9266551b98ee3522536f54c71e11c 442 Gene3D G3DSA:1.25.40.590 15 157 2.0E-19 T 12-10-2018 IPR038522 Type IV / VI secretion system, DotU superfamily VAPA_1c06300 2ae9266551b98ee3522536f54c71e11c 442 Pfam PF09850 Type VI secretion system protein DotU 10 209 4.7E-22 T 12-10-2018 IPR017732 Type IV / VI secretion system, DotU VAPA_1c19290 824e21e82df23de6c775fc0fb708f61a 345 Pfam PF02653 Branched-chain amino acid transport system / permease component 51 319 1.7E-35 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 VAPA_1c50420 03d83eb78421bc4e2d75c2faa03f0831 258 Gene3D G3DSA:1.10.3720.10 56 252 1.6E-20 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c50420 03d83eb78421bc4e2d75c2faa03f0831 258 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 82 250 6.9E-19 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 VAPA_1c50420 03d83eb78421bc4e2d75c2faa03f0831 258 SUPERFAMILY SSF161098 58 242 5.63E-26 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c50360 197c2562b9ddc1465268ae9c4396cb02 301 Gene3D G3DSA:1.10.10.10 5 90 3.8E-22 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c50360 197c2562b9ddc1465268ae9c4396cb02 301 SUPERFAMILY SSF53850 91 299 1.85E-34 T 12-10-2018 VAPA_1c50360 197c2562b9ddc1465268ae9c4396cb02 301 Pfam PF03466 LysR substrate binding domain 89 296 5.2E-36 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_1c50360 197c2562b9ddc1465268ae9c4396cb02 301 Gene3D G3DSA:3.40.190.290 92 300 2.9E-39 T 12-10-2018 VAPA_1c50360 197c2562b9ddc1465268ae9c4396cb02 301 SUPERFAMILY SSF46785 3 112 3.13E-20 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c50360 197c2562b9ddc1465268ae9c4396cb02 301 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 64 5.8E-17 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c11690 343e863dd89525704ea26a1b34c56b40 262 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 258 4.1E-59 T 12-10-2018 VAPA_1c11690 343e863dd89525704ea26a1b34c56b40 262 SUPERFAMILY SSF51735 6 260 8.57E-78 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c11690 343e863dd89525704ea26a1b34c56b40 262 Gene3D G3DSA:3.40.50.720 7 261 1.3E-79 T 12-10-2018 VAPA_1c11690 343e863dd89525704ea26a1b34c56b40 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 138 146 4.7E-7 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c11690 343e863dd89525704ea26a1b34c56b40 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 4.7E-7 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c11690 343e863dd89525704ea26a1b34c56b40 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 158 177 4.7E-7 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c11690 343e863dd89525704ea26a1b34c56b40 262 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 145 173 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 VAPA_1c11690 343e863dd89525704ea26a1b34c56b40 262 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 8 189 5.9E-5 T 12-10-2018 VAPA_1c11690 343e863dd89525704ea26a1b34c56b40 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 7.8E-38 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c11690 343e863dd89525704ea26a1b34c56b40 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 7.8E-38 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c11690 343e863dd89525704ea26a1b34c56b40 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 7.8E-38 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c11690 343e863dd89525704ea26a1b34c56b40 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 7.8E-38 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c11690 343e863dd89525704ea26a1b34c56b40 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 223 243 7.8E-38 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c11690 343e863dd89525704ea26a1b34c56b40 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 7.8E-38 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c32160 e07d70a7fc0015882068287d15b41d30 750 Pfam PF05506 Domain of unknown function (DUF756) 652 731 2.2E-22 T 12-10-2018 IPR008475 Bacterial phospholipase C, C-terminal domain GO:0004629|GO:0016042 KEGG: 00562+3.1.4.3|KEGG: 00564+3.1.4.3|KEGG: 00565+3.1.4.3|MetaCyc: PWY-7782|MetaCyc: PWY-7783 VAPA_1c32160 e07d70a7fc0015882068287d15b41d30 750 Pfam PF05506 Domain of unknown function (DUF756) 554 641 5.3E-23 T 12-10-2018 IPR008475 Bacterial phospholipase C, C-terminal domain GO:0004629|GO:0016042 KEGG: 00562+3.1.4.3|KEGG: 00564+3.1.4.3|KEGG: 00565+3.1.4.3|MetaCyc: PWY-7782|MetaCyc: PWY-7783 VAPA_1c32160 e07d70a7fc0015882068287d15b41d30 750 TIGRFAM TIGR03396 PC_PLC: phospholipase C, phosphocholine-specific 5 745 5.0E-268 T 12-10-2018 IPR017767 Bacterial phospholipase C, phosphocholine-specific GO:0034480 KEGG: 00562+3.1.4.3|KEGG: 00564+3.1.4.3|KEGG: 00565+3.1.4.3|MetaCyc: PWY-7782|MetaCyc: PWY-7783 VAPA_1c32160 e07d70a7fc0015882068287d15b41d30 750 Gene3D G3DSA:3.40.720.10 222 529 4.5E-44 T 12-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 VAPA_1c32160 e07d70a7fc0015882068287d15b41d30 750 Gene3D G3DSA:3.40.720.10 37 185 2.6E-30 T 12-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 VAPA_1c32160 e07d70a7fc0015882068287d15b41d30 750 Pfam PF04185 Phosphoesterase family 48 480 4.8E-104 T 12-10-2018 IPR007312 Phosphoesterase GO:0016788 VAPA_1c52580 d16661d55d11f33221bd4621875c60af 210 PIRSF PIRSF006324 1 207 1.8E-52 T 12-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 VAPA_1c52580 d16661d55d11f33221bd4621875c60af 210 Pfam PF01810 LysE type translocator 15 204 1.1E-28 T 12-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 VAPA_2c10820 28916f1049b1f0ab792d423c663f6887 274 Gene3D G3DSA:3.20.20.140 2 274 2.2E-67 T 12-10-2018 VAPA_2c10820 28916f1049b1f0ab792d423c663f6887 274 SUPERFAMILY SSF51556 11 274 6.81E-58 T 12-10-2018 IPR032466 Metal-dependent hydrolase VAPA_2c10820 28916f1049b1f0ab792d423c663f6887 274 Pfam PF04909 Amidohydrolase 12 274 4.4E-25 T 12-10-2018 IPR006680 Amidohydrolase-related GO:0016787 VAPA_1c13380 befa818fd497645b5280b28c508c1a99 262 Gene3D G3DSA:3.90.226.10 7 205 2.8E-69 T 12-10-2018 VAPA_1c13380 befa818fd497645b5280b28c508c1a99 262 Gene3D G3DSA:1.10.12.10 206 262 3.8E-23 T 12-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal VAPA_1c13380 befa818fd497645b5280b28c508c1a99 262 Pfam PF00378 Enoyl-CoA hydratase/isomerase 16 261 1.3E-53 T 12-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 VAPA_1c13380 befa818fd497645b5280b28c508c1a99 262 SUPERFAMILY SSF52096 8 261 1.45E-78 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily VAPA_1c48710 448475621ca652cbf99d00f48906f34a 306 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 101 269 9.0E-43 T 12-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 VAPA_1c48710 448475621ca652cbf99d00f48906f34a 306 Gene3D G3DSA:3.40.50.720 90 272 2.0E-105 T 12-10-2018 VAPA_1c48710 448475621ca652cbf99d00f48906f34a 306 SUPERFAMILY SSF51735 92 271 3.01E-45 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c48710 448475621ca652cbf99d00f48906f34a 306 Gene3D G3DSA:3.40.50.720 15 306 2.0E-105 T 12-10-2018 VAPA_1c30680 e055cf9bad232b2d7c8501efc6a68049 240 Pfam PF00440 Bacterial regulatory proteins, tetR family 25 70 2.7E-14 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 VAPA_1c30680 e055cf9bad232b2d7c8501efc6a68049 240 SUPERFAMILY SSF46689 13 78 2.05E-17 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 VAPA_1c30680 e055cf9bad232b2d7c8501efc6a68049 240 Gene3D G3DSA:1.10.357.10 8 216 5.9E-29 T 12-10-2018 VAPA_1c30680 e055cf9bad232b2d7c8501efc6a68049 240 SUPERFAMILY SSF48498 91 216 2.52E-7 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily VAPA_1c30680 e055cf9bad232b2d7c8501efc6a68049 240 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 25 38 6.8E-7 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 VAPA_1c30680 e055cf9bad232b2d7c8501efc6a68049 240 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 46 69 6.8E-7 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 VAPA_1c30680 e055cf9bad232b2d7c8501efc6a68049 240 Pfam PF09209 Domain of unknown function (DUF1956) 95 214 1.2E-14 T 12-10-2018 IPR015292 Transcription regulator YbiH, C-terminal VAPA_1c04230 52e70c8f5ed04af68fca636281a1593c 324 Gene3D G3DSA:3.40.190.150 31 313 3.9E-83 T 12-10-2018 VAPA_1c04230 52e70c8f5ed04af68fca636281a1593c 324 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 51 320 7.3E-61 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c04230 52e70c8f5ed04af68fca636281a1593c 324 Gene3D G3DSA:3.40.190.10 128 249 3.9E-83 T 12-10-2018 VAPA_1c04230 52e70c8f5ed04af68fca636281a1593c 324 PIRSF PIRSF017082 1 324 1.6E-57 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c18900 c3e46618a9cbf1887d24dea1a14f6bcb 135 Pfam PF03928 Haem-degrading 7 130 7.8E-29 T 12-10-2018 IPR005624 Haem-degrading VAPA_1c18900 c3e46618a9cbf1887d24dea1a14f6bcb 135 SUPERFAMILY SSF143744 2 134 5.62E-36 T 12-10-2018 IPR038084 GlcG-like domain superfamily VAPA_1c18900 c3e46618a9cbf1887d24dea1a14f6bcb 135 Gene3D G3DSA:3.30.450.150 1 135 9.9E-37 T 12-10-2018 IPR038084 GlcG-like domain superfamily VAPA_1c14700 424f81c480b8269d259b175359ff9db6 427 Gene3D G3DSA:1.25.40.10 342 427 8.9E-7 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 VAPA_1c14700 424f81c480b8269d259b175359ff9db6 427 TIGRFAM TIGR00540 TPR_hemY_coli: heme biosynthesis-associated TPR protein 3 420 3.5E-75 T 12-10-2018 IPR005254 Heme biosynthesis-associated TPR protein GO:0016020|GO:0042168 VAPA_1c14700 424f81c480b8269d259b175359ff9db6 427 Pfam PF07219 HemY protein N-terminus 26 144 6.4E-25 T 12-10-2018 IPR010817 HemY, N-terminal VAPA_1c29940 9122d5594bd41380ebb4f7465681d9b6 158 SUPERFAMILY SSF82784 1 152 9.16E-46 T 12-10-2018 IPR036102 OsmC/Ohr superfamily VAPA_1c29940 9122d5594bd41380ebb4f7465681d9b6 158 Gene3D G3DSA:3.30.300.20 1 152 2.2E-48 T 12-10-2018 IPR015946 K homology domain-like, alpha/beta VAPA_1c29940 9122d5594bd41380ebb4f7465681d9b6 158 Pfam PF02566 OsmC-like protein 52 151 1.0E-14 T 12-10-2018 IPR003718 OsmC/Ohr family VAPA_2c11330 cc5fc8f102b12fb1b88b4620adb3e613 457 SUPERFAMILY SSF46785 148 252 3.54E-13 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_2c11330 cc5fc8f102b12fb1b88b4620adb3e613 457 Pfam PF01051 Initiator Replication protein 21 248 1.7E-17 T 12-10-2018 IPR000525 Initiator Rep protein GO:0003887|GO:0005727|GO:0006270 VAPA_2c07780 95ed5655316667cb5b0401650e1857da 414 Pfam PF07690 Major Facilitator Superfamily 25 284 6.9E-30 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 VAPA_2c07780 95ed5655316667cb5b0401650e1857da 414 SUPERFAMILY SSF103473 16 400 3.14E-61 T 12-10-2018 IPR036259 MFS transporter superfamily VAPA_2c07780 95ed5655316667cb5b0401650e1857da 414 Gene3D G3DSA:1.20.1250.20 10 405 1.0E-52 T 12-10-2018 VAPA_2c03260 3de1088fa26798bce44b8f978f999746 115 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 17 61 4.5E-6 T 12-10-2018 VAPA_2c03260 3de1088fa26798bce44b8f978f999746 115 SUPERFAMILY SSF143120 15 64 1.96E-5 T 12-10-2018 IPR036165 YefM-like superfamily VAPA_2c03260 3de1088fa26798bce44b8f978f999746 115 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 16 73 1.2E-6 T 12-10-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM VAPA_1c29460 b93e33ce08d6106d6613501580b906f8 456 Gene3D G3DSA:2.30.42.10 226 315 4.9E-15 T 12-10-2018 VAPA_1c29460 b93e33ce08d6106d6613501580b906f8 456 Pfam PF02163 Peptidase family M50 6 441 2.8E-70 T 12-10-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 VAPA_1c29460 b93e33ce08d6106d6613501580b906f8 456 SUPERFAMILY SSF50156 210 298 1.45E-11 T 12-10-2018 IPR036034 PDZ superfamily GO:0005515 VAPA_1c29460 b93e33ce08d6106d6613501580b906f8 456 TIGRFAM TIGR00054 TIGR00054: RIP metalloprotease RseP 1 455 1.2E-91 T 12-10-2018 IPR004387 Peptidase M50, putative membrane-associated zinc metallopeptidase GO:0004222|GO:0006508|GO:0016021 VAPA_1c49220 09285fd9f3ad08e111c20905ebf14d7e 375 Gene3D G3DSA:3.10.180.10 10 170 2.6E-54 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase VAPA_1c49220 09285fd9f3ad08e111c20905ebf14d7e 375 PIRSF PIRSF009283 5 372 1.4E-118 T 12-10-2018 IPR005956 4-hydroxyphenylpyruvate dioxygenase GO:0003868|GO:0009072|GO:0016701|GO:0055114 VAPA_1c49220 09285fd9f3ad08e111c20905ebf14d7e 375 TIGRFAM TIGR01263 4HPPD: 4-hydroxyphenylpyruvate dioxygenase 20 371 8.4E-117 T 12-10-2018 IPR005956 4-hydroxyphenylpyruvate dioxygenase GO:0003868|GO:0009072|GO:0016701|GO:0055114 VAPA_1c49220 09285fd9f3ad08e111c20905ebf14d7e 375 SUPERFAMILY SSF54593 10 358 2.23E-79 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase VAPA_1c49220 09285fd9f3ad08e111c20905ebf14d7e 375 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 181 292 7.7E-13 T 12-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain VAPA_1c49220 09285fd9f3ad08e111c20905ebf14d7e 375 Pfam PF14696 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal 12 160 1.9E-64 T 12-10-2018 VAPA_1c49220 09285fd9f3ad08e111c20905ebf14d7e 375 Gene3D G3DSA:3.10.180.10 176 372 2.2E-64 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase VAPA_1c40340 d6092e6f085d8abc9d49de44b0a61563 399 Gene3D G3DSA:2.120.10.30 71 389 2.4E-23 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like VAPA_1c40340 d6092e6f085d8abc9d49de44b0a61563 399 Pfam PF07995 Glucose / Sorbosone dehydrogenase 182 326 7.7E-12 T 12-10-2018 IPR012938 Glucose/Sorbosone dehydrogenase VAPA_1c40340 d6092e6f085d8abc9d49de44b0a61563 399 SUPERFAMILY SSF50952 63 398 2.48E-28 T 12-10-2018 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 VAPA_1c05920 7c1abb01d9a9daae65ffced7a65c403f 443 Pfam PF05936 Bacterial Type VI secretion, VC_A0110, EvfL, ImpJ, VasE 19 441 4.7E-150 T 12-10-2018 IPR010263 Type VI secretion protein, VC_A0114 VAPA_1c05920 7c1abb01d9a9daae65ffced7a65c403f 443 TIGRFAM TIGR03353 VI_chp_4: type VI secretion protein, VC_A0114 family 6 442 1.2E-147 T 12-10-2018 IPR010263 Type VI secretion protein, VC_A0114 VAPA_2c12300 b6c9601a3f8633850b9f695d7536ee9e 242 Pfam PF00005 ABC transporter 27 170 5.3E-30 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_2c12300 b6c9601a3f8633850b9f695d7536ee9e 242 SMART SM00382 36 221 4.6E-12 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_2c12300 b6c9601a3f8633850b9f695d7536ee9e 242 SUPERFAMILY SSF52540 9 235 4.47E-56 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_2c12300 b6c9601a3f8633850b9f695d7536ee9e 242 ProSitePatterns PS00211 ABC transporters family signature. 143 157 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_2c12300 b6c9601a3f8633850b9f695d7536ee9e 242 Gene3D G3DSA:3.40.50.300 7 242 7.1E-56 T 12-10-2018 VAPA_1c29290 83069d6ca79f4e1596aec07c4445c545 222 Hamap MF_01547 Ribosomal RNA large subunit methyltransferase E [rlmE]. 16 217 30.767 T 12-10-2018 IPR015507 Ribosomal RNA large subunit methyltransferase E GO:0001510|GO:0008168 VAPA_1c29290 83069d6ca79f4e1596aec07c4445c545 222 PIRSF PIRSF005461 1 222 2.6E-70 T 12-10-2018 IPR015507 Ribosomal RNA large subunit methyltransferase E GO:0001510|GO:0008168 VAPA_1c29290 83069d6ca79f4e1596aec07c4445c545 222 Pfam PF01728 FtsJ-like methyltransferase 32 215 5.3E-54 T 12-10-2018 IPR002877 Ribosomal RNA methyltransferase FtsJ domain GO:0008168|GO:0032259 VAPA_1c29290 83069d6ca79f4e1596aec07c4445c545 222 Gene3D G3DSA:3.40.50.150 31 221 1.2E-60 T 12-10-2018 VAPA_1c29290 83069d6ca79f4e1596aec07c4445c545 222 SUPERFAMILY SSF53335 31 216 1.09E-37 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase VAPA_1c33380 8cdbf390e4693b5ab7de100e8e660f12 213 Gene3D G3DSA:1.20.120.1760 23 172 4.3E-12 T 12-10-2018 VAPA_1c33380 8cdbf390e4693b5ab7de100e8e660f12 213 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 70 92 - T 12-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 VAPA_1c33380 8cdbf390e4693b5ab7de100e8e660f12 213 Pfam PF01066 CDP-alcohol phosphatidyltransferase 22 92 4.0E-12 T 12-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 VAPA_1c21840 907644eb391f4e4e0c557424d64fb6d4 435 SUPERFAMILY SSF51556 18 353 1.25E-103 T 12-10-2018 IPR032466 Metal-dependent hydrolase VAPA_1c21840 907644eb391f4e4e0c557424d64fb6d4 435 Gene3D G3DSA:2.30.40.10 4 423 4.3E-159 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 VAPA_1c21840 907644eb391f4e4e0c557424d64fb6d4 435 TIGRFAM TIGR02033 D-hydantoinase: dihydropyrimidinase 5 424 1.7E-148 T 12-10-2018 IPR011778 Hydantoinase/dihydropyrimidinase GO:0005737 Reactome: R-HSA-399956 VAPA_1c21840 907644eb391f4e4e0c557424d64fb6d4 435 SUPERFAMILY SSF51338 322 423 1.16E-24 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 VAPA_1c21840 907644eb391f4e4e0c557424d64fb6d4 435 Gene3D G3DSA:3.20.20.140 18 393 4.3E-159 T 12-10-2018 VAPA_1c21840 907644eb391f4e4e0c557424d64fb6d4 435 Pfam PF01979 Amidohydrolase family 14 406 4.0E-27 T 12-10-2018 IPR006680 Amidohydrolase-related GO:0016787 VAPA_1c10050 235612a65f9b16760efbb5e0cac2658f 300 Pfam PF00294 pfkB family carbohydrate kinase 38 290 3.1E-35 T 12-10-2018 IPR011611 Carbohydrate kinase PfkB VAPA_1c10050 235612a65f9b16760efbb5e0cac2658f 300 SUPERFAMILY SSF53613 3 291 4.52E-59 T 12-10-2018 IPR029056 Ribokinase-like VAPA_1c10050 235612a65f9b16760efbb5e0cac2658f 300 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 47 71 - T 12-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 VAPA_1c10050 235612a65f9b16760efbb5e0cac2658f 300 Gene3D G3DSA:3.40.1190.20 1 299 6.1E-100 T 12-10-2018 IPR029056 Ribokinase-like VAPA_1c46470 3fcf936f7fc1a641ed6d65342db5a1e0 643 Gene3D G3DSA:3.10.20.310 245 320 1.2E-9 T 12-10-2018 VAPA_1c46470 3fcf936f7fc1a641ed6d65342db5a1e0 643 Gene3D G3DSA:2.40.160.50 321 642 5.9E-53 T 12-10-2018 VAPA_1c46470 3fcf936f7fc1a641ed6d65342db5a1e0 643 Pfam PF01103 Surface antigen 429 643 1.2E-24 T 12-10-2018 IPR000184 Bacterial surface antigen (D15) GO:0019867 Reactome: R-HSA-1268020|Reactome: R-HSA-8949613 VAPA_1c28600 087b8032811d2d6c8212ff7dc803d974 209 SUPERFAMILY SSF52374 8 208 2.66E-47 T 12-10-2018 VAPA_1c28600 087b8032811d2d6c8212ff7dc803d974 209 TIGRFAM TIGR00482 TIGR00482: nicotinate (nicotinamide) nucleotide adenylyltransferase 12 206 2.5E-43 T 12-10-2018 IPR005248 Nicotinate/nicotinamide nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 VAPA_1c28600 087b8032811d2d6c8212ff7dc803d974 209 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 10 67 2.9E-10 T 12-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 VAPA_1c28600 087b8032811d2d6c8212ff7dc803d974 209 Hamap MF_00244 Probable nicotinate-nucleotide adenylyltransferase [nadD]. 8 207 27.481 T 12-10-2018 IPR005248 Nicotinate/nicotinamide nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 VAPA_1c28600 087b8032811d2d6c8212ff7dc803d974 209 Gene3D G3DSA:3.40.50.620 7 208 6.9E-55 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold VAPA_1c28600 087b8032811d2d6c8212ff7dc803d974 209 Pfam PF01467 Cytidylyltransferase-like 12 181 1.5E-21 T 12-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 VAPA_1c10030 72a4d36dd872ea2cd56f3de023512120 294 TIGRFAM TIGR00406 prmA: ribosomal protein L11 methyltransferase 2 285 7.7E-61 T 12-10-2018 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 VAPA_1c10030 72a4d36dd872ea2cd56f3de023512120 294 Gene3D G3DSA:3.40.50.150 107 294 2.7E-57 T 12-10-2018 VAPA_1c10030 72a4d36dd872ea2cd56f3de023512120 294 PIRSF PIRSF000401 1 294 4.8E-76 T 12-10-2018 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 VAPA_1c10030 72a4d36dd872ea2cd56f3de023512120 294 SUPERFAMILY SSF53335 92 274 1.36E-37 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase VAPA_1c10030 72a4d36dd872ea2cd56f3de023512120 294 Hamap MF_00735 Ribosomal protein L11 methyltransferase [prmA]. 1 294 29.408 T 12-10-2018 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 VAPA_1c10030 72a4d36dd872ea2cd56f3de023512120 294 Pfam PF06325 Ribosomal protein L11 methyltransferase (PrmA) 2 292 1.1E-74 T 12-10-2018 VAPA_1c37760 c1c0e6f01a302d76d2434fec9f5f2c55 94 Gene3D G3DSA:2.170.150.40 1 93 3.7E-27 T 12-10-2018 VAPA_1c37760 c1c0e6f01a302d76d2434fec9f5f2c55 94 Pfam PF04248 Domain of unknown function (DUF427) 1 88 2.2E-31 T 12-10-2018 IPR007361 Domain of unknown function DUF427 VAPA_2c12220 62f9a1312c1cdce64e413a621fd768e6 382 SUPERFAMILY SSF53822 26 368 5.38E-71 T 12-10-2018 IPR028082 Periplasmic binding protein-like I VAPA_2c12220 62f9a1312c1cdce64e413a621fd768e6 382 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 49 65 3.7E-7 T 12-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 VAPA_2c12220 62f9a1312c1cdce64e413a621fd768e6 382 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 277 290 3.7E-7 T 12-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 VAPA_2c12220 62f9a1312c1cdce64e413a621fd768e6 382 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 27 43 3.7E-7 T 12-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 VAPA_2c12220 62f9a1312c1cdce64e413a621fd768e6 382 Pfam PF13458 Periplasmic binding protein 26 361 1.4E-69 T 12-10-2018 IPR028081 Leucine-binding protein domain VAPA_2c12220 62f9a1312c1cdce64e413a621fd768e6 382 Gene3D G3DSA:3.40.50.2300 29 353 3.0E-84 T 12-10-2018 VAPA_2c12220 62f9a1312c1cdce64e413a621fd768e6 382 Gene3D G3DSA:3.40.50.2300 141 368 3.0E-84 T 12-10-2018 VAPA_1c17690 e93ca7eb9ab16e7cdcf03534a5907c99 146 Gene3D G3DSA:3.10.580.10 1 141 7.3E-33 T 12-10-2018 VAPA_1c17690 e93ca7eb9ab16e7cdcf03534a5907c99 146 SMART SM00116 13 60 9.3E-6 T 12-10-2018 IPR000644 CBS domain VAPA_1c17690 e93ca7eb9ab16e7cdcf03534a5907c99 146 SMART SM00116 78 125 0.42 T 12-10-2018 IPR000644 CBS domain VAPA_1c17690 e93ca7eb9ab16e7cdcf03534a5907c99 146 SUPERFAMILY SSF54631 1 143 3.92E-28 T 12-10-2018 VAPA_1c17690 e93ca7eb9ab16e7cdcf03534a5907c99 146 Pfam PF00571 CBS domain 71 125 2.1E-7 T 12-10-2018 IPR000644 CBS domain VAPA_1c17690 e93ca7eb9ab16e7cdcf03534a5907c99 146 Pfam PF00571 CBS domain 15 60 5.9E-8 T 12-10-2018 IPR000644 CBS domain VAPA_1c37770 4f0d54bfecb5d7ff1fcece15ee731b9b 337 Pfam PF10017 Histidine-specific methyltransferase, SAM-dependent 37 335 3.7E-109 T 12-10-2018 IPR019257 Histidine-specific methyltransferase, SAM-dependent VAPA_1c37770 4f0d54bfecb5d7ff1fcece15ee731b9b 337 Gene3D G3DSA:3.40.50.150 63 241 1.5E-50 T 12-10-2018 VAPA_1c37770 4f0d54bfecb5d7ff1fcece15ee731b9b 337 SUPERFAMILY SSF53335 53 325 4.51E-14 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase VAPA_1c37770 4f0d54bfecb5d7ff1fcece15ee731b9b 337 PIRSF PIRSF018005 10 336 3.7E-116 T 12-10-2018 IPR017804 Methyltransferase EgtD-like GO:0008168 VAPA_1c37770 4f0d54bfecb5d7ff1fcece15ee731b9b 337 TIGRFAM TIGR03438 egtD_ergothio: dimethylhistidine N-methyltransferase 36 335 9.7E-126 T 12-10-2018 IPR035094 Histidine N-alpha-methyltransferase KEGG: 00340+2.1.1.44|MetaCyc: PWY-7255|MetaCyc: PWY-7550 VAPA_1c45740 0d73e771e836af6e121c26770f625174 288 Pfam PF04909 Amidohydrolase 9 286 3.8E-56 T 12-10-2018 IPR006680 Amidohydrolase-related GO:0016787 VAPA_1c45740 0d73e771e836af6e121c26770f625174 288 Gene3D G3DSA:3.20.20.140 6 286 4.6E-63 T 12-10-2018 VAPA_1c45740 0d73e771e836af6e121c26770f625174 288 SUPERFAMILY SSF51556 9 286 2.69E-69 T 12-10-2018 IPR032466 Metal-dependent hydrolase VAPA_1c43580 f903c405b77c959aa9fc994f2f243890 98 TIGRFAM TIGR03824 FlgM_jcvi: flagellar biosynthesis anti-sigma factor FlgM 10 88 2.1E-12 T 12-10-2018 IPR007412 Anti-sigma-28 factor, FlgM GO:0045892 VAPA_1c43580 f903c405b77c959aa9fc994f2f243890 98 Pfam PF04316 Anti-sigma-28 factor, FlgM 41 85 4.6E-9 T 12-10-2018 IPR031316 Anti-sigma-28 factor FlgM, C-terminal VAPA_1c43580 f903c405b77c959aa9fc994f2f243890 98 SUPERFAMILY SSF101498 16 88 6.67E-10 T 12-10-2018 IPR035890 Anti-sigma-28 factor FlgM superfamily VAPA_2c09610 0e807062daf0576b8886fcd21c687af2 461 TIGRFAM TIGR00170 leuC: 3-isopropylmalate dehydratase, large subunit 3 456 2.2E-173 T 12-10-2018 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 VAPA_2c09610 0e807062daf0576b8886fcd21c687af2 461 Gene3D G3DSA:3.30.499.10 320 461 1.2E-47 T 12-10-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 KEGG: 00290+4.2.1.33 VAPA_2c09610 0e807062daf0576b8886fcd21c687af2 461 ProSitePatterns PS00450 Aconitase family signature 1. 331 347 - T 12-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 VAPA_2c09610 0e807062daf0576b8886fcd21c687af2 461 Pfam PF00330 Aconitase family (aconitate hydratase) 8 449 1.7E-132 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 VAPA_2c09610 0e807062daf0576b8886fcd21c687af2 461 ProSitePatterns PS01244 Aconitase family signature 2. 391 404 - T 12-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 VAPA_2c09610 0e807062daf0576b8886fcd21c687af2 461 SUPERFAMILY SSF53732 3 458 2.49E-146 T 12-10-2018 IPR036008 Aconitase, iron-sulfur domain KEGG: 00290+4.2.1.33 VAPA_2c09610 0e807062daf0576b8886fcd21c687af2 461 Gene3D G3DSA:3.30.499.20 5 285 1.6E-84 T 12-10-2018 VAPA_2c09610 0e807062daf0576b8886fcd21c687af2 461 PRINTS PR00415 Aconitase family signature 285 299 1.5E-40 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 VAPA_2c09610 0e807062daf0576b8886fcd21c687af2 461 PRINTS PR00415 Aconitase family signature 194 207 1.5E-40 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 VAPA_2c09610 0e807062daf0576b8886fcd21c687af2 461 PRINTS PR00415 Aconitase family signature 132 147 1.5E-40 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 VAPA_2c09610 0e807062daf0576b8886fcd21c687af2 461 PRINTS PR00415 Aconitase family signature 107 115 1.5E-40 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 VAPA_2c09610 0e807062daf0576b8886fcd21c687af2 461 PRINTS PR00415 Aconitase family signature 118 131 1.5E-40 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 VAPA_2c09610 0e807062daf0576b8886fcd21c687af2 461 PRINTS PR00415 Aconitase family signature 335 346 1.5E-40 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 VAPA_2c09610 0e807062daf0576b8886fcd21c687af2 461 PRINTS PR00415 Aconitase family signature 391 404 1.5E-40 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 VAPA_2c09610 0e807062daf0576b8886fcd21c687af2 461 PRINTS PR00415 Aconitase family signature 208 221 1.5E-40 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 VAPA_2c11870 c79b70819a827a6924eb32bfc0e04f3d 59 SUPERFAMILY SSF46894 2 55 1.08E-9 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 VAPA_2c11870 c79b70819a827a6924eb32bfc0e04f3d 59 Pfam PF00486 Transcriptional regulatory protein, C terminal 1 53 7.6E-11 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 VAPA_2c11870 c79b70819a827a6924eb32bfc0e04f3d 59 Gene3D G3DSA:1.10.10.10 1 57 1.2E-10 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c05420 1c7ad050f566dee4132e5fbcfdfb46e1 244 SUPERFAMILY SSF110997 167 242 1.7E-18 T 12-10-2018 IPR036680 Sporulation-like domain superfamily GO:0042834 VAPA_1c05420 1c7ad050f566dee4132e5fbcfdfb46e1 244 Gene3D G3DSA:3.30.70.1070 164 243 7.7E-18 T 12-10-2018 IPR036680 Sporulation-like domain superfamily GO:0042834 VAPA_1c05420 1c7ad050f566dee4132e5fbcfdfb46e1 244 Pfam PF05036 Sporulation related domain 170 241 3.5E-17 T 12-10-2018 IPR007730 Sporulation-like domain GO:0042834 VAPA_1c29230 35b13860cd4e280006775e9cd6ab5f4e 362 Gene3D G3DSA:3.30.200.20 19 122 2.6E-38 T 12-10-2018 VAPA_1c29230 35b13860cd4e280006775e9cd6ab5f4e 362 SUPERFAMILY SSF56112 4 331 1.48E-57 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily VAPA_1c29230 35b13860cd4e280006775e9cd6ab5f4e 362 Pfam PF01636 Phosphotransferase enzyme family 42 271 2.1E-51 T 12-10-2018 IPR002575 Aminoglycoside phosphotransferase VAPA_1c29230 35b13860cd4e280006775e9cd6ab5f4e 362 Gene3D G3DSA:3.90.1200.10 123 362 6.6E-94 T 12-10-2018 VAPA_2c11200 a0e2711dd25c871a7e6450791f912a9d 544 Pfam PF02538 Hydantoinase B/oxoprolinase 9 522 8.8E-145 T 12-10-2018 IPR003692 Hydantoinase B/oxoprolinase GO:0003824 Reactome: R-HSA-174403|Reactome: R-HSA-5578998 VAPA_1c36070 8966234185dd87b48c59486b95cbf691 677 Pfam PF00361 Proton-conducting membrane transporter 143 431 1.7E-82 T 12-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VAPA_1c36070 8966234185dd87b48c59486b95cbf691 677 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 74 131 2.0E-26 T 12-10-2018 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VAPA_1c36070 8966234185dd87b48c59486b95cbf691 677 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 92 117 4.6E-65 T 12-10-2018 VAPA_1c36070 8966234185dd87b48c59486b95cbf691 677 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 240 261 4.6E-65 T 12-10-2018 VAPA_1c36070 8966234185dd87b48c59486b95cbf691 677 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 120 140 4.6E-65 T 12-10-2018 VAPA_1c36070 8966234185dd87b48c59486b95cbf691 677 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 167 188 4.6E-65 T 12-10-2018 VAPA_1c36070 8966234185dd87b48c59486b95cbf691 677 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 262 288 4.6E-65 T 12-10-2018 VAPA_1c36070 8966234185dd87b48c59486b95cbf691 677 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 435 454 4.6E-65 T 12-10-2018 VAPA_1c36070 8966234185dd87b48c59486b95cbf691 677 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 330 342 4.6E-65 T 12-10-2018 VAPA_1c36070 8966234185dd87b48c59486b95cbf691 677 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 68 92 1.2E-12 T 12-10-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 VAPA_1c36070 8966234185dd87b48c59486b95cbf691 677 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 434 456 1.2E-12 T 12-10-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 VAPA_1c36070 8966234185dd87b48c59486b95cbf691 677 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 280 302 1.2E-12 T 12-10-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 VAPA_1c36070 8966234185dd87b48c59486b95cbf691 677 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 94 114 1.2E-12 T 12-10-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 VAPA_1c36070 8966234185dd87b48c59486b95cbf691 677 TIGRFAM TIGR01974 NDH_I_L: proton-translocating NADH-quinone oxidoreductase, chain L 12 672 5.2E-242 T 12-10-2018 IPR003945 NADH-plastoquinone oxidoreductase, chain 5 GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VAPA_1c43160 4b2062621a4a871b858e64cba1e84f91 118 ProDom PD015582 ACTIVATOR TRANSCRIPTIONAL TRANSCRIPTION FLAGELLUM FLHD FLAGELLAR DNA-BINDING REGULATION REGULATOR PROBABLE 18 105 4.0E-22 T 12-10-2018 IPR023559 Flagellar transcriptional activator FlhD GO:0044780|GO:0045893 VAPA_1c43160 4b2062621a4a871b858e64cba1e84f91 118 Pfam PF05247 Flagellar transcriptional activator (FlhD) 12 108 2.3E-35 T 12-10-2018 IPR023559 Flagellar transcriptional activator FlhD GO:0044780|GO:0045893 VAPA_1c43160 4b2062621a4a871b858e64cba1e84f91 118 Gene3D G3DSA:1.10.4000.10 9 118 2.0E-35 T 12-10-2018 IPR036194 Flagellar transcriptional activator FlhD superfamily VAPA_1c43160 4b2062621a4a871b858e64cba1e84f91 118 SUPERFAMILY SSF63592 11 105 2.48E-31 T 12-10-2018 IPR036194 Flagellar transcriptional activator FlhD superfamily VAPA_1c43160 4b2062621a4a871b858e64cba1e84f91 118 Hamap MF_00725 Flagellar transcriptional regulator FlhD [flhD]. 9 112 23.188 T 12-10-2018 IPR023559 Flagellar transcriptional activator FlhD GO:0044780|GO:0045893 VAPA_1c45540 ea9617a2120347b35259091532d41c43 209 SUPERFAMILY SSF52833 50 208 8.31E-52 T 12-10-2018 IPR036249 Thioredoxin-like superfamily VAPA_1c45540 ea9617a2120347b35259091532d41c43 209 Gene3D G3DSA:3.40.30.10 41 209 4.6E-52 T 12-10-2018 VAPA_1c45540 ea9617a2120347b35259091532d41c43 209 Pfam PF02630 SCO1/SenC 51 186 1.9E-37 T 12-10-2018 IPR003782 Copper chaperone SCO1/SenC Reactome: R-HSA-5628897|Reactome: R-HSA-611105 VAPA_1c39090 4a0e24445c18a7df5ceea0bda7b65b41 220 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 49 220 2.2E-15 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 VAPA_1c39090 4a0e24445c18a7df5ceea0bda7b65b41 220 SUPERFAMILY SSF161098 10 207 2.22E-38 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c39090 4a0e24445c18a7df5ceea0bda7b65b41 220 Gene3D G3DSA:1.10.3720.10 8 220 5.8E-41 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c31820 4a01982f3170dc4615287c9c8b6bee1f 152 PIRSF PIRSF003230 1 146 2.1E-40 T 12-10-2018 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 VAPA_1c31820 4a01982f3170dc4615287c9c8b6bee1f 152 Gene3D G3DSA:3.10.129.10 1 144 1.3E-40 T 12-10-2018 VAPA_1c31820 4a01982f3170dc4615287c9c8b6bee1f 152 SUPERFAMILY SSF54637 2 140 2.24E-35 T 12-10-2018 IPR029069 HotDog domain superfamily VAPA_1c31820 4a01982f3170dc4615287c9c8b6bee1f 152 Pfam PF03061 Thioesterase superfamily 17 100 1.9E-16 T 12-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 VAPA_1c31820 4a01982f3170dc4615287c9c8b6bee1f 152 TIGRFAM TIGR00051 TIGR00051: acyl-CoA thioester hydrolase, YbgC/YbaW family 6 105 1.1E-28 T 12-10-2018 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 VAPA_1c23440 4f61ca7365e1939af67e89823528f19a 195 Gene3D G3DSA:3.90.1720.10 49 182 2.5E-41 T 12-10-2018 VAPA_1c23440 4f61ca7365e1939af67e89823528f19a 195 SUPERFAMILY SSF54001 49 175 3.92E-43 T 12-10-2018 IPR038765 Papain-like cysteine peptidase superfamily VAPA_1c23440 4f61ca7365e1939af67e89823528f19a 195 Pfam PF00877 NlpC/P60 family 65 172 4.1E-30 T 12-10-2018 IPR000064 Endopeptidase, NLPC/P60 domain VAPA_1c10500 ec9cc5800580fa84943523b14729668f 192 SUPERFAMILY SSF56672 60 187 7.89E-20 T 12-10-2018 VAPA_1c10500 ec9cc5800580fa84943523b14729668f 192 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 112 189 2.4E-13 T 12-10-2018 IPR000477 Reverse transcriptase domain VAPA_1c13500 2d7025a9b0a76214d99b405806076134 319 TIGRFAM TIGR01292 TRX_reduct: thioredoxin-disulfide reductase 8 313 4.9E-118 T 12-10-2018 IPR005982 Thioredoxin reductase GO:0004791|GO:0005737|GO:0019430|GO:0055114 KEGG: 00450+1.8.1.9 VAPA_1c13500 2d7025a9b0a76214d99b405806076134 319 SUPERFAMILY SSF51905 1 313 3.3E-50 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c13500 2d7025a9b0a76214d99b405806076134 319 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 8 301 1.5E-48 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 VAPA_1c13500 2d7025a9b0a76214d99b405806076134 319 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 106 124 1.1E-37 T 12-10-2018 VAPA_1c13500 2d7025a9b0a76214d99b405806076134 319 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 266 288 1.1E-37 T 12-10-2018 VAPA_1c13500 2d7025a9b0a76214d99b405806076134 319 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 9 28 1.1E-37 T 12-10-2018 VAPA_1c13500 2d7025a9b0a76214d99b405806076134 319 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 236 252 1.1E-37 T 12-10-2018 VAPA_1c13500 2d7025a9b0a76214d99b405806076134 319 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 148 166 1.1E-37 T 12-10-2018 VAPA_1c13500 2d7025a9b0a76214d99b405806076134 319 Gene3D G3DSA:3.50.50.60 118 244 6.8E-121 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c13500 2d7025a9b0a76214d99b405806076134 319 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 276 294 5.0E-72 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 VAPA_1c13500 2d7025a9b0a76214d99b405806076134 319 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 41 56 5.0E-72 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 VAPA_1c13500 2d7025a9b0a76214d99b405806076134 319 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 129 141 5.0E-72 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 VAPA_1c13500 2d7025a9b0a76214d99b405806076134 319 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 62 72 5.0E-72 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 VAPA_1c13500 2d7025a9b0a76214d99b405806076134 319 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 107 115 5.0E-72 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 VAPA_1c13500 2d7025a9b0a76214d99b405806076134 319 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 8 30 5.0E-72 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 VAPA_1c13500 2d7025a9b0a76214d99b405806076134 319 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 238 259 5.0E-72 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 VAPA_1c13500 2d7025a9b0a76214d99b405806076134 319 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 144 168 5.0E-72 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 VAPA_1c13500 2d7025a9b0a76214d99b405806076134 319 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 199 215 5.0E-72 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 VAPA_1c13500 2d7025a9b0a76214d99b405806076134 319 ProSitePatterns PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 136 156 - T 12-10-2018 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site GO:0016491|GO:0055114 VAPA_1c13500 2d7025a9b0a76214d99b405806076134 319 Gene3D G3DSA:3.50.50.60 10 312 6.8E-121 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_2c00160 687a020b743f0a82fda00bd1ae01bc63 264 SUPERFAMILY SSF52096 2 254 3.37E-66 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily VAPA_2c00160 687a020b743f0a82fda00bd1ae01bc63 264 Gene3D G3DSA:3.90.226.10 3 256 1.3E-62 T 12-10-2018 VAPA_2c00160 687a020b743f0a82fda00bd1ae01bc63 264 Pfam PF00378 Enoyl-CoA hydratase/isomerase 14 254 1.9E-47 T 12-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 VAPA_2c00160 687a020b743f0a82fda00bd1ae01bc63 264 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 102 122 - T 12-10-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824 VAPA_1c24700 053a648215e64c401b9a137303e6bfa2 110 Pfam PF02575 YbaB/EbfC DNA-binding family 11 99 1.7E-35 T 12-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family VAPA_1c24700 053a648215e64c401b9a137303e6bfa2 110 Hamap MF_00274 Nucleoid-associated protein YbaB [ybaB]. 5 98 22.993 T 12-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family VAPA_1c24700 053a648215e64c401b9a137303e6bfa2 110 Gene3D G3DSA:3.30.1310.10 1 110 9.6E-44 T 12-10-2018 IPR036894 Nucleoid-associated protein YbaB-like domain superfamily VAPA_1c24700 053a648215e64c401b9a137303e6bfa2 110 SUPERFAMILY SSF82607 11 103 1.03E-33 T 12-10-2018 IPR036894 Nucleoid-associated protein YbaB-like domain superfamily VAPA_1c24700 053a648215e64c401b9a137303e6bfa2 110 PIRSF PIRSF004555 3 110 3.9E-38 T 12-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family VAPA_1c24700 053a648215e64c401b9a137303e6bfa2 110 TIGRFAM TIGR00103 DNA_YbaB_EbfC: DNA-binding protein, YbaB/EbfC family 1 102 3.6E-33 T 12-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family VAPA_1c55110 f3de1da87a3264a4b9bb10f9ef9b47fb 95 ProDom PD004225 UPF0161 ALPHA-HEMOLYSIN YIDD UNCHARACTERIZED CYTOSOLIC PRECURSOR SIGNAL YTJA RNPA SIMILAR 15 68 3.0E-18 T 12-10-2018 IPR002696 Putative membrane protein insertion efficiency factor VAPA_1c55110 f3de1da87a3264a4b9bb10f9ef9b47fb 95 SMART SM01234 1 68 1.1E-42 T 12-10-2018 IPR002696 Putative membrane protein insertion efficiency factor VAPA_1c55110 f3de1da87a3264a4b9bb10f9ef9b47fb 95 Pfam PF01809 Haemolytic domain 2 68 7.3E-28 T 12-10-2018 IPR002696 Putative membrane protein insertion efficiency factor VAPA_1c55110 f3de1da87a3264a4b9bb10f9ef9b47fb 95 TIGRFAM TIGR00278 TIGR00278: putative membrane protein insertion efficiency factor 5 75 8.3E-28 T 12-10-2018 IPR002696 Putative membrane protein insertion efficiency factor VAPA_1c55110 f3de1da87a3264a4b9bb10f9ef9b47fb 95 Hamap MF_00386 Putative membrane protein insertion efficiency factor [yidD]. 1 69 23.072 T 12-10-2018 IPR002696 Putative membrane protein insertion efficiency factor VAPA_1c54760 302356cd8aada9dfbaccbdefab026716 514 Pfam PF01564 Spermine/spermidine synthase domain 275 452 4.7E-33 T 12-10-2018 VAPA_1c54760 302356cd8aada9dfbaccbdefab026716 514 Hamap MF_00198 Polyamine aminopropyltransferase [speE]. 192 496 24.395 T 12-10-2018 IPR001045 Spermidine/spermine synthases GO:0003824 KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 VAPA_1c54760 302356cd8aada9dfbaccbdefab026716 514 SUPERFAMILY SSF53335 225 486 4.17E-63 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase VAPA_1c54760 302356cd8aada9dfbaccbdefab026716 514 Gene3D G3DSA:3.40.50.150 270 506 1.2E-59 T 12-10-2018 VAPA_1c54760 302356cd8aada9dfbaccbdefab026716 514 ProSitePatterns PS01330 Polyamine biosynthesis (PABS) domain signature. 295 308 - T 12-10-2018 IPR030373 Polyamine biosynthesis domain, conserved site KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 VAPA_1c53420 3c495df1a91c671d2452900676b7f166 749 Pfam PF05787 Bacterial protein of unknown function (DUF839) 83 702 3.0E-128 T 12-10-2018 IPR008557 Protein of unknown function DUF839 VAPA_1c15220 ba9606aff05b51cd135c16b904a90a1a 121 SUPERFAMILY SSF81343 9 121 8.72E-30 T 12-10-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 VAPA_1c15220 ba9606aff05b51cd135c16b904a90a1a 121 Gene3D G3DSA:1.20.1300.10 8 121 1.7E-29 T 12-10-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 VAPA_1c15220 ba9606aff05b51cd135c16b904a90a1a 121 Pfam PF01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 11 108 6.4E-12 T 12-10-2018 IPR000701 Succinate dehydrogenase/fumarate reductase type B, transmembrane subunit GO:0016627 Reactome: R-HSA-611105|Reactome: R-HSA-71403 VAPA_1c15220 ba9606aff05b51cd135c16b904a90a1a 121 TIGRFAM TIGR02968 succ_dehyd_anc: succinate dehydrogenase, hydrophobic membrane anchor protein 14 119 1.3E-32 T 12-10-2018 IPR014312 Succinate dehydrogenase, hydrophobic membrane anchor GO:0000104|GO:0006099|GO:0016021|GO:0020037 VAPA_1c15220 ba9606aff05b51cd135c16b904a90a1a 121 PIRSF PIRSF000169 6 121 4.8E-34 T 12-10-2018 IPR014312 Succinate dehydrogenase, hydrophobic membrane anchor GO:0000104|GO:0006099|GO:0016021|GO:0020037 VAPA_1c44400 0947143d5974b7f8abd2123bc6a3dfe1 338 Gene3D G3DSA:3.30.920.90 38 116 6.9E-7 T 12-10-2018 VAPA_1c44400 0947143d5974b7f8abd2123bc6a3dfe1 338 Pfam PF01844 HNH endonuclease 260 317 9.2E-5 T 12-10-2018 IPR002711 HNH endonuclease GO:0003676|GO:0004519 VAPA_1c44400 0947143d5974b7f8abd2123bc6a3dfe1 338 Pfam PF12102 Domain of unknown function (DUF3578) 10 199 7.9E-34 T 12-10-2018 IPR021961 Protein of unknown function DUF3578 VAPA_1c44400 0947143d5974b7f8abd2123bc6a3dfe1 338 SUPERFAMILY SSF48695 256 330 8.17E-5 T 12-10-2018 IPR036280 Multiheme cytochrome superfamily VAPA_2c09500 3f1c2684af540ba9fd823e133c8cb6c2 522 Pfam PF13005 zinc-finger binding domain of transposase IS66 118 161 1.9E-15 T 12-10-2018 IPR024474 Zinc-finger binding domain of transposase IS66 VAPA_2c09500 3f1c2684af540ba9fd823e133c8cb6c2 522 Pfam PF13817 IS66 C-terminal element 471 508 1.2E-18 T 12-10-2018 IPR039552 Transposase IS66, C-terminal VAPA_2c09500 3f1c2684af540ba9fd823e133c8cb6c2 522 Pfam PF13007 Transposase C of IS166 homeodomain 35 98 1.8E-7 T 12-10-2018 IPR024463 Transposase TnpC, homeodomain VAPA_2c09500 3f1c2684af540ba9fd823e133c8cb6c2 522 Pfam PF03050 Transposase IS66 family 176 464 2.3E-96 T 12-10-2018 IPR004291 Transposase, IS66 VAPA_2c00980 4d9aff1c47ff373d3b9a7df4585627c5 231 Pfam PF00156 Phosphoribosyl transferase domain 60 159 1.5E-8 T 12-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 VAPA_2c00980 4d9aff1c47ff373d3b9a7df4585627c5 231 SUPERFAMILY SSF53271 23 216 4.15E-39 T 12-10-2018 IPR029057 Phosphoribosyltransferase-like VAPA_2c00980 4d9aff1c47ff373d3b9a7df4585627c5 231 Hamap MF_01208 Orotate phosphoribosyltransferase [pyrE]. 1 231 22.03 T 12-10-2018 IPR023031 Orotate phosphoribosyltransferase GO:0004588|GO:0006221 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 VAPA_2c00980 4d9aff1c47ff373d3b9a7df4585627c5 231 Gene3D G3DSA:3.40.50.2020 3 225 6.4E-52 T 12-10-2018 VAPA_1c28860 25387a5d1b62e849a79a0652f3e186bd 333 Gene3D G3DSA:3.40.50.2300 47 291 1.0E-66 T 12-10-2018 VAPA_1c28860 25387a5d1b62e849a79a0652f3e186bd 333 SUPERFAMILY SSF53822 37 230 6.59E-5 T 12-10-2018 IPR028082 Periplasmic binding protein-like I VAPA_1c28860 25387a5d1b62e849a79a0652f3e186bd 333 Gene3D G3DSA:3.40.50.2300 134 318 1.0E-66 T 12-10-2018 VAPA_1c28860 25387a5d1b62e849a79a0652f3e186bd 333 Pfam PF02608 ABC transporter substrate-binding protein PnrA-like 50 269 3.8E-39 T 12-10-2018 IPR003760 ABC transporter substrate-binding protein PnrA-like GO:0005886 VAPA_1c18700 88795c1f0e16f3542ad246391e103c4f 295 Pfam PF00892 EamA-like transporter family 162 291 5.0E-14 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 VAPA_1c18700 88795c1f0e16f3542ad246391e103c4f 295 Pfam PF00892 EamA-like transporter family 20 145 2.6E-12 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 VAPA_1c18700 88795c1f0e16f3542ad246391e103c4f 295 SUPERFAMILY SSF103481 47 148 1.44E-8 T 12-10-2018 VAPA_1c18700 88795c1f0e16f3542ad246391e103c4f 295 SUPERFAMILY SSF103481 194 294 1.57E-12 T 12-10-2018 VAPA_1c08090 d2e0f4f64bfa9a8dd025160e43b2e1ca 199 Pfam PF01810 LysE type translocator 15 193 1.1E-9 T 12-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 VAPA_2c12240 0392ee7c32b502626561317d152c1fbf 602 Pfam PF00005 ABC transporter 372 528 1.1E-17 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_2c12240 0392ee7c32b502626561317d152c1fbf 602 Gene3D G3DSA:3.40.50.300 352 601 5.8E-45 T 12-10-2018 VAPA_2c12240 0392ee7c32b502626561317d152c1fbf 602 ProSitePatterns PS00211 ABC transporters family signature. 500 514 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_2c12240 0392ee7c32b502626561317d152c1fbf 602 SUPERFAMILY SSF52540 356 597 3.62E-44 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_2c12240 0392ee7c32b502626561317d152c1fbf 602 Pfam PF02653 Branched-chain amino acid transport system / permease component 55 316 4.7E-32 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 VAPA_1c53790 7607671907e24e1368cb6cfa2e35f0a3 387 Gene3D G3DSA:3.40.640.10 2 260 1.5E-92 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 VAPA_1c53790 7607671907e24e1368cb6cfa2e35f0a3 387 SUPERFAMILY SSF53383 7 386 2.53E-113 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase VAPA_1c53790 7607671907e24e1368cb6cfa2e35f0a3 387 Gene3D G3DSA:3.90.1150.10 261 387 5.9E-39 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 VAPA_1c53790 7607671907e24e1368cb6cfa2e35f0a3 387 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 16 382 2.9E-132 T 12-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase VAPA_1c53790 7607671907e24e1368cb6cfa2e35f0a3 387 PIRSF PIRSF000390 5 387 3.0E-115 T 12-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase VAPA_1c04990 9d902dd84757e98f434750414b41f164 201 Pfam PF02627 Carboxymuconolactone decarboxylase family 66 136 1.8E-10 T 12-10-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 VAPA_1c04990 9d902dd84757e98f434750414b41f164 201 SUPERFAMILY SSF69118 13 191 8.86E-41 T 12-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 VAPA_1c04990 9d902dd84757e98f434750414b41f164 201 Gene3D G3DSA:1.20.1290.10 77 198 9.1E-35 T 12-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 VAPA_1c04990 9d902dd84757e98f434750414b41f164 201 TIGRFAM TIGR01926 peroxid_rel: uncharacterized peroxidase-related enzyme 19 193 3.7E-60 T 12-10-2018 IPR010195 Uncharacterised peroxidase-related VAPA_1c13340 69563fe351bcccfd1764e2d443a1bcfc 170 TIGRFAM TIGR00077 lspA: signal peptidase II 19 164 4.6E-42 T 12-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 VAPA_1c13340 69563fe351bcccfd1764e2d443a1bcfc 170 Pfam PF01252 Signal peptidase (SPase) II 24 162 2.5E-38 T 12-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 VAPA_1c13340 69563fe351bcccfd1764e2d443a1bcfc 170 ProSitePatterns PS00855 Signal peptidases II signature. 111 123 - T 12-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 VAPA_1c13340 69563fe351bcccfd1764e2d443a1bcfc 170 Hamap MF_00161 Lipoprotein signal peptidase [lspA]. 15 169 16.602 T 12-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 VAPA_1c13340 69563fe351bcccfd1764e2d443a1bcfc 170 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 61 69 2.8E-17 T 12-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 VAPA_1c13340 69563fe351bcccfd1764e2d443a1bcfc 170 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 144 160 2.8E-17 T 12-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 VAPA_1c13340 69563fe351bcccfd1764e2d443a1bcfc 170 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 108 123 2.8E-17 T 12-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 VAPA_1c02540 ae07a18e59177f9fd854ae498bcb9cad 115 Pfam PF05717 IS66 Orf2 like protein 9 105 1.3E-39 T 12-10-2018 IPR008878 Transposase IS66, Orf2 VAPA_2c09490 ae07a18e59177f9fd854ae498bcb9cad 115 Pfam PF05717 IS66 Orf2 like protein 9 105 1.3E-39 T 12-10-2018 IPR008878 Transposase IS66, Orf2 VAPA_2c09540 7fed60a439360aa57460a72fe6ee63b6 578 PIRSF PIRSF029745 3 578 1.1E-150 T 12-10-2018 IPR027282 Two partner secretion pathway transporter GO:0015031 VAPA_2c09540 7fed60a439360aa57460a72fe6ee63b6 578 Pfam PF08479 POTRA domain, ShlB-type 105 156 1.2E-12 T 12-10-2018 IPR013686 Polypeptide-transport-associated, ShlB-type VAPA_2c09540 7fed60a439360aa57460a72fe6ee63b6 578 Pfam PF03865 Haemolysin secretion/activation protein ShlB/FhaC/HecB 225 542 1.7E-110 T 12-10-2018 IPR005565 Haemolysin activator HlyB, C-terminal VAPA_2c09540 7fed60a439360aa57460a72fe6ee63b6 578 Pfam PF17287 POTRA domain 157 216 1.2E-17 T 12-10-2018 IPR035251 ShlB, POTRA domain VAPA_2c09540 7fed60a439360aa57460a72fe6ee63b6 578 Gene3D G3DSA:2.40.160.50 194 578 2.2E-106 T 12-10-2018 VAPA_1c27800 9899afa73157891b90f2a74b3bf66e68 302 Pfam PF03466 LysR substrate binding domain 88 290 9.4E-42 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_1c27800 9899afa73157891b90f2a74b3bf66e68 302 Gene3D G3DSA:3.40.190.10 89 289 1.8E-58 T 12-10-2018 VAPA_1c27800 9899afa73157891b90f2a74b3bf66e68 302 Gene3D G3DSA:1.10.10.10 1 86 1.0E-26 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c27800 9899afa73157891b90f2a74b3bf66e68 302 Gene3D G3DSA:3.40.190.10 164 271 1.8E-58 T 12-10-2018 VAPA_1c27800 9899afa73157891b90f2a74b3bf66e68 302 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 63 1.0E-16 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c27800 9899afa73157891b90f2a74b3bf66e68 302 SUPERFAMILY SSF53850 88 297 5.13E-40 T 12-10-2018 VAPA_1c27800 9899afa73157891b90f2a74b3bf66e68 302 SUPERFAMILY SSF46785 3 87 2.37E-19 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c23990 66f63307924cd8a01b435880a909f33d 260 SUPERFAMILY SSF51735 4 259 3.66E-72 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c23990 66f63307924cd8a01b435880a909f33d 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 1.9E-28 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c23990 66f63307924cd8a01b435880a909f33d 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 1.9E-28 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c23990 66f63307924cd8a01b435880a909f33d 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 1.9E-28 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c23990 66f63307924cd8a01b435880a909f33d 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 1.9E-28 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c23990 66f63307924cd8a01b435880a909f33d 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 1.9E-28 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c23990 66f63307924cd8a01b435880a909f33d 260 Pfam PF00106 short chain dehydrogenase 6 198 3.7E-56 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c23990 66f63307924cd8a01b435880a909f33d 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 2.4E-8 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c23990 66f63307924cd8a01b435880a909f33d 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 2.4E-8 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c23990 66f63307924cd8a01b435880a909f33d 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 2.4E-8 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c23990 66f63307924cd8a01b435880a909f33d 260 TIGRFAM TIGR01963 PHB_DH: 3-hydroxybutyrate dehydrogenase 6 260 1.3E-100 T 12-10-2018 IPR011294 3-hydroxybutyrate dehydrogenase GO:0003858|GO:0055114 VAPA_1c23990 66f63307924cd8a01b435880a909f33d 260 Gene3D G3DSA:3.40.50.720 1 260 3.3E-78 T 12-10-2018 VAPA_1c23990 66f63307924cd8a01b435880a909f33d 260 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 142 170 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 VAPA_1c12180 17c085106a7af8946f7fb6406451f0eb 90 Gene3D G3DSA:3.30.750.24 1 90 4.3E-12 T 12-10-2018 IPR036513 STAS domain superfamily VAPA_1c12180 17c085106a7af8946f7fb6406451f0eb 90 Pfam PF13466 STAS domain 2 82 3.7E-19 T 12-10-2018 IPR002645 STAS domain VAPA_1c12180 17c085106a7af8946f7fb6406451f0eb 90 SUPERFAMILY SSF52091 2 87 1.29E-11 T 12-10-2018 IPR036513 STAS domain superfamily VAPA_1c46450 75f32424733d1b56c662be2bcf6bdbfa 198 Gene3D G3DSA:3.40.630.30 1 192 7.5E-44 T 12-10-2018 VAPA_1c46450 75f32424733d1b56c662be2bcf6bdbfa 198 SUPERFAMILY SSF55729 5 177 2.92E-36 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase VAPA_1c46450 75f32424733d1b56c662be2bcf6bdbfa 198 Pfam PF13302 Acetyltransferase (GNAT) domain 14 153 3.2E-18 T 12-10-2018 IPR000182 GNAT domain VAPA_1c03550 9eac18492540037da99d8e92822f0688 287 Pfam PF09339 IclR helix-turn-helix domain 16 66 1.7E-9 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 VAPA_1c03550 9eac18492540037da99d8e92822f0688 287 Pfam PF01614 Bacterial transcriptional regulator 198 269 1.1E-9 T 12-10-2018 IPR014757 Transcription regulator IclR, C-terminal VAPA_1c03550 9eac18492540037da99d8e92822f0688 287 SUPERFAMILY SSF46785 14 87 1.13E-11 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c03550 9eac18492540037da99d8e92822f0688 287 SMART SM00346 14 104 1.5E-11 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 VAPA_1c03550 9eac18492540037da99d8e92822f0688 287 Gene3D G3DSA:3.30.450.40 92 270 8.8E-35 T 12-10-2018 IPR029016 GAF-like domain superfamily VAPA_1c03550 9eac18492540037da99d8e92822f0688 287 SUPERFAMILY SSF55781 80 273 7.19E-37 T 12-10-2018 VAPA_1c03550 9eac18492540037da99d8e92822f0688 287 Gene3D G3DSA:1.10.10.10 8 82 5.1E-13 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c22830 6b6172a23cd3c7b09602631f111b1eee 257 SUPERFAMILY SSF56529 2 253 3.05E-63 T 12-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 VAPA_1c22830 6b6172a23cd3c7b09602631f111b1eee 257 Gene3D G3DSA:3.90.850.10 1 254 6.2E-69 T 12-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 VAPA_1c22830 6b6172a23cd3c7b09602631f111b1eee 257 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 88 253 1.2E-11 T 12-10-2018 IPR011234 Fumarylacetoacetase-like, C-terminal GO:0003824 VAPA_1c07200 3cbd39af000902f8ca2681d47c24494a 987 Gene3D G3DSA:3.40.50.300 17 205 2.4E-24 T 12-10-2018 VAPA_1c07200 3cbd39af000902f8ca2681d47c24494a 987 Gene3D G3DSA:3.40.50.300 237 392 9.5E-17 T 12-10-2018 VAPA_1c07200 3cbd39af000902f8ca2681d47c24494a 987 Pfam PF04851 Type III restriction enzyme, res subunit 25 189 1.6E-16 T 12-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 VAPA_1c07200 3cbd39af000902f8ca2681d47c24494a 987 SUPERFAMILY SSF52540 43 359 9.84E-31 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c07200 3cbd39af000902f8ca2681d47c24494a 987 Pfam PF00271 Helicase conserved C-terminal domain 262 349 5.6E-5 T 12-10-2018 IPR001650 Helicase, C-terminal VAPA_1c07200 3cbd39af000902f8ca2681d47c24494a 987 SMART SM00490 269 350 0.0054 T 12-10-2018 IPR001650 Helicase, C-terminal VAPA_1c07200 3cbd39af000902f8ca2681d47c24494a 987 SMART SM00487 21 221 2.5E-13 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain VAPA_1c43290 25d04805b8eff1aa790a16d8cfb3b1fe 151 PIRSF PIRSF019404 1 148 7.1E-47 T 12-10-2018 IPR018006 Flagellar FliJ, proteobacteria GO:0003774|GO:0006935|GO:0009288|GO:0016020|GO:0071973 VAPA_1c43290 25d04805b8eff1aa790a16d8cfb3b1fe 151 TIGRFAM TIGR02473 flagell_FliJ: flagellar export protein FliJ 6 142 7.8E-27 T 12-10-2018 IPR012823 Flagellar export FliJ GO:0009288|GO:0071973 VAPA_1c43290 25d04805b8eff1aa790a16d8cfb3b1fe 151 PRINTS PR01004 Flagellar FliJ protein signature 86 107 1.3E-11 T 12-10-2018 IPR018006 Flagellar FliJ, proteobacteria GO:0003774|GO:0006935|GO:0009288|GO:0016020|GO:0071973 VAPA_1c43290 25d04805b8eff1aa790a16d8cfb3b1fe 151 PRINTS PR01004 Flagellar FliJ protein signature 4 26 1.3E-11 T 12-10-2018 IPR018006 Flagellar FliJ, proteobacteria GO:0003774|GO:0006935|GO:0009288|GO:0016020|GO:0071973 VAPA_1c43290 25d04805b8eff1aa790a16d8cfb3b1fe 151 PRINTS PR01004 Flagellar FliJ protein signature 63 84 1.3E-11 T 12-10-2018 IPR018006 Flagellar FliJ, proteobacteria GO:0003774|GO:0006935|GO:0009288|GO:0016020|GO:0071973 VAPA_1c43290 25d04805b8eff1aa790a16d8cfb3b1fe 151 PRINTS PR01004 Flagellar FliJ protein signature 44 61 1.3E-11 T 12-10-2018 IPR018006 Flagellar FliJ, proteobacteria GO:0003774|GO:0006935|GO:0009288|GO:0016020|GO:0071973 VAPA_1c43290 25d04805b8eff1aa790a16d8cfb3b1fe 151 Pfam PF02050 Flagellar FliJ protein 19 142 2.3E-31 T 12-10-2018 IPR012823 Flagellar export FliJ GO:0009288|GO:0071973 VAPA_1c39820 8adb3e2881abff0d3c041beba33b6912 321 SMART SM00062 37 264 0.007 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF VAPA_1c39820 8adb3e2881abff0d3c041beba33b6912 321 Pfam PF13379 NMT1-like family 59 261 7.8E-13 T 12-10-2018 VAPA_1c39820 8adb3e2881abff0d3c041beba33b6912 321 TIGRFAM TIGR01728 SsuA_fam: ABC transporter, substrate-binding protein, aliphatic sulfonates family 49 317 1.1E-58 T 12-10-2018 IPR010067 Aliphatic sulfonates-binding protein GO:0016020|GO:0042626 VAPA_1c39820 8adb3e2881abff0d3c041beba33b6912 321 Gene3D G3DSA:3.40.190.10 38 306 2.8E-84 T 12-10-2018 VAPA_1c39820 8adb3e2881abff0d3c041beba33b6912 321 SUPERFAMILY SSF53850 52 258 4.06E-37 T 12-10-2018 VAPA_1c39820 8adb3e2881abff0d3c041beba33b6912 321 Gene3D G3DSA:1.10.8.450 244 276 2.8E-84 T 12-10-2018 VAPA_1c39820 8adb3e2881abff0d3c041beba33b6912 321 Gene3D G3DSA:3.40.190.10 113 212 2.8E-84 T 12-10-2018 VAPA_1c09190 36d900676794ebfe26dab8f65074fc53 343 Gene3D G3DSA:3.20.20.140 3 343 3.9E-105 T 12-10-2018 VAPA_1c09190 36d900676794ebfe26dab8f65074fc53 343 ProSitePatterns PS00482 Dihydroorotase signature 1. 12 20 - T 12-10-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 VAPA_1c09190 36d900676794ebfe26dab8f65074fc53 343 Pfam PF01979 Amidohydrolase family 12 311 9.9E-19 T 12-10-2018 IPR006680 Amidohydrolase-related GO:0016787 VAPA_1c09190 36d900676794ebfe26dab8f65074fc53 343 SUPERFAMILY SSF51556 5 342 1.23E-142 T 12-10-2018 IPR032466 Metal-dependent hydrolase VAPA_1c09190 36d900676794ebfe26dab8f65074fc53 343 PIRSF PIRSF001237 1 343 2.8E-134 T 12-10-2018 IPR004721 Dihydroorotase homodimeric type GO:0004151|GO:0019856 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 VAPA_1c09190 36d900676794ebfe26dab8f65074fc53 343 Hamap MF_00219 Dihydroorotase [pyrC]. 3 343 45.543 T 12-10-2018 IPR004721 Dihydroorotase homodimeric type GO:0004151|GO:0019856 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 VAPA_1c09190 36d900676794ebfe26dab8f65074fc53 343 TIGRFAM TIGR00856 pyrC_dimer: dihydroorotase, homodimeric type 5 342 1.0E-135 T 12-10-2018 IPR004721 Dihydroorotase homodimeric type GO:0004151|GO:0019856 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 VAPA_1c09190 36d900676794ebfe26dab8f65074fc53 343 ProSitePatterns PS00483 Dihydroorotase signature 2. 245 256 - T 12-10-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 VAPA_2c06770 34228707ce0c4da2c5429ecc35738d44 557 Pfam PF01494 FAD binding domain 38 373 4.7E-62 T 12-10-2018 IPR002938 FAD-binding domain GO:0071949 VAPA_2c06770 34228707ce0c4da2c5429ecc35738d44 557 SUPERFAMILY SSF51905 38 409 7.2E-62 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_2c06770 34228707ce0c4da2c5429ecc35738d44 557 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 186 201 8.8E-33 T 12-10-2018 VAPA_2c06770 34228707ce0c4da2c5429ecc35738d44 557 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 311 326 8.8E-33 T 12-10-2018 VAPA_2c06770 34228707ce0c4da2c5429ecc35738d44 557 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 38 60 8.8E-33 T 12-10-2018 VAPA_2c06770 34228707ce0c4da2c5429ecc35738d44 557 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 326 342 8.8E-33 T 12-10-2018 VAPA_2c06770 34228707ce0c4da2c5429ecc35738d44 557 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 344 362 8.8E-33 T 12-10-2018 VAPA_2c06770 34228707ce0c4da2c5429ecc35738d44 557 Gene3D G3DSA:3.40.30.120 414 554 2.7E-14 T 12-10-2018 VAPA_2c06770 34228707ce0c4da2c5429ecc35738d44 557 Gene3D G3DSA:3.30.70.2450 215 300 1.9E-92 T 12-10-2018 VAPA_2c06770 34228707ce0c4da2c5429ecc35738d44 557 Gene3D G3DSA:3.50.50.60 39 372 1.9E-92 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c15970 047f2ab3c1dc36bacf284fe93beb8714 351 Pfam PF02653 Branched-chain amino acid transport system / permease component 12 331 8.3E-17 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 VAPA_1c16410 dd8eab274dfeb7b8289b8932d75489e2 295 Gene3D G3DSA:3.40.190.10 23 269 2.9E-98 T 12-10-2018 VAPA_1c16410 dd8eab274dfeb7b8289b8932d75489e2 295 SUPERFAMILY SSF53850 1 267 1.05E-63 T 12-10-2018 VAPA_1c16410 dd8eab274dfeb7b8289b8932d75489e2 295 SMART SM00062 34 266 1.3E-50 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF VAPA_1c16410 dd8eab274dfeb7b8289b8932d75489e2 295 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 35 263 4.9E-46 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF VAPA_1c16410 dd8eab274dfeb7b8289b8932d75489e2 295 Gene3D G3DSA:3.40.190.10 128 223 2.9E-98 T 12-10-2018 VAPA_1c35500 5d1bcb0dffebbddc18de0a9dbc271abf 559 Pfam PF06418 CTP synthase N-terminus 3 270 3.4E-123 T 12-10-2018 IPR017456 CTP synthase, N-terminal GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 VAPA_1c35500 5d1bcb0dffebbddc18de0a9dbc271abf 559 Gene3D G3DSA:3.40.50.300 1 289 1.6E-128 T 12-10-2018 VAPA_1c35500 5d1bcb0dffebbddc18de0a9dbc271abf 559 Pfam PF00117 Glutamine amidotransferase class-I 305 540 9.0E-54 T 12-10-2018 IPR017926 Glutamine amidotransferase VAPA_1c35500 5d1bcb0dffebbddc18de0a9dbc271abf 559 SUPERFAMILY SSF52540 1 272 5.31E-119 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c35500 5d1bcb0dffebbddc18de0a9dbc271abf 559 Gene3D G3DSA:3.40.50.880 290 550 2.9E-98 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like VAPA_1c35500 5d1bcb0dffebbddc18de0a9dbc271abf 559 TIGRFAM TIGR00337 PyrG: CTP synthase 1 540 3.0E-235 T 12-10-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 VAPA_1c35500 5d1bcb0dffebbddc18de0a9dbc271abf 559 SUPERFAMILY SSF52317 292 546 3.15E-79 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like VAPA_1c35500 5d1bcb0dffebbddc18de0a9dbc271abf 559 Hamap MF_01227 CTP synthase [pyrG]. 2 545 50.601 T 12-10-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 VAPA_1c05240 1f89bfc36ca9d889b864344e9d51a454 106 Pfam PF11142 Protein of unknown function (DUF2917) 26 69 1.3E-12 T 12-10-2018 IPR021317 Protein of unknown function DUF2917 VAPA_1c05100 527afd8c938a351b726c506ecd257735 146 Gene3D G3DSA:3.10.450.50 16 140 1.8E-10 T 12-10-2018 VAPA_1c05100 527afd8c938a351b726c506ecd257735 146 SUPERFAMILY SSF54427 17 137 1.14E-12 T 12-10-2018 IPR032710 NTF2-like domain superfamily VAPA_1c26560 3288ad37cfe314f302f1957e66725e90 157 SUPERFAMILY SSF46458 8 120 1.54E-24 T 12-10-2018 IPR009050 Globin-like superfamily VAPA_1c26560 3288ad37cfe314f302f1957e66725e90 157 Pfam PF01152 Bacterial-like globin 9 104 7.0E-18 T 12-10-2018 IPR001486 Truncated hemoglobin GO:0019825 VAPA_1c26560 3288ad37cfe314f302f1957e66725e90 157 Gene3D G3DSA:1.10.490.10 6 133 8.6E-31 T 12-10-2018 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 VAPA_1c19100 f2178bdf9b925c672e4274c1ef86a65c 149 Gene3D G3DSA:3.10.590.10 2 138 1.0E-23 T 12-10-2018 VAPA_1c19100 f2178bdf9b925c672e4274c1ef86a65c 149 Hamap MF_00771 UPF0310 protein . 3 140 23.185 T 12-10-2018 IPR022996 Uncharacterised protein family UPF0310 VAPA_1c19100 f2178bdf9b925c672e4274c1ef86a65c 149 Pfam PF01878 EVE domain 5 138 4.6E-9 T 12-10-2018 IPR002740 EVE domain VAPA_1c19100 f2178bdf9b925c672e4274c1ef86a65c 149 SUPERFAMILY SSF88697 4 140 3.83E-25 T 12-10-2018 IPR015947 PUA-like superfamily VAPA_1c50630 705eeb5080ba06b27c4270ec9afa7a0b 226 Hamap MF_00013 Octanoyltransferase [lipB]. 4 223 34.024 T 12-10-2018 IPR000544 Octanoyltransferase GO:0009249|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 VAPA_1c50630 705eeb5080ba06b27c4270ec9afa7a0b 226 PIRSF PIRSF016262 1 226 8.2E-56 T 12-10-2018 IPR000544 Octanoyltransferase GO:0009249|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 VAPA_1c50630 705eeb5080ba06b27c4270ec9afa7a0b 226 TIGRFAM TIGR00214 lipB: lipoyl(octanoyl) transferase 29 131 2.3E-32 T 12-10-2018 IPR000544 Octanoyltransferase GO:0009249|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 VAPA_1c50630 705eeb5080ba06b27c4270ec9afa7a0b 226 SUPERFAMILY SSF55681 5 223 1.24E-61 T 12-10-2018 VAPA_1c50630 705eeb5080ba06b27c4270ec9afa7a0b 226 ProSitePatterns PS01313 Lipoate-protein ligase B signature. 70 85 - T 12-10-2018 IPR020605 Octanoyltransferase, conserved site GO:0009249|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 VAPA_1c50630 705eeb5080ba06b27c4270ec9afa7a0b 226 ProDom PD006086 LIGASE LIPOATE-PROTEIN B TRANSFERASE ACYLTRANSFERASE LIPOYLTRANSFERASE LIPOYL-ACYL-CARRIER 2.3.1.- PROTEIN-PROTEIN- N-LIPOYLTRANSFERASE 74 127 4.0E-21 T 12-10-2018 VAPA_1c50630 705eeb5080ba06b27c4270ec9afa7a0b 226 Pfam PF03099 Biotin/lipoate A/B protein ligase family 57 180 1.3E-8 T 12-10-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 VAPA_1c50630 705eeb5080ba06b27c4270ec9afa7a0b 226 Gene3D G3DSA:3.30.930.10 1 225 2.0E-59 T 12-10-2018 VAPA_1c20590 a422d17c3bd80013ea899819dea567e6 169 SMART SM00972 105 166 3.8E-7 T 12-10-2018 IPR007893 Spore coat protein U VAPA_1c20590 a422d17c3bd80013ea899819dea567e6 169 Pfam PF05229 Spore Coat Protein U domain 27 165 2.9E-26 T 12-10-2018 IPR007893 Spore coat protein U VAPA_2c04330 4218df3c3f7cdbdbdf2a0247e4ef6529 280 Pfam PF00582 Universal stress protein family 157 279 3.5E-9 T 12-10-2018 IPR006016 UspA VAPA_2c04330 4218df3c3f7cdbdbdf2a0247e4ef6529 280 PRINTS PR01438 Universal stress protein signature 3 21 2.1E-9 T 12-10-2018 IPR006015 Universal stress protein A VAPA_2c04330 4218df3c3f7cdbdbdf2a0247e4ef6529 280 PRINTS PR01438 Universal stress protein signature 258 280 2.1E-9 T 12-10-2018 IPR006015 Universal stress protein A VAPA_2c04330 4218df3c3f7cdbdbdf2a0247e4ef6529 280 PRINTS PR01438 Universal stress protein signature 240 252 2.1E-9 T 12-10-2018 IPR006015 Universal stress protein A VAPA_2c04330 4218df3c3f7cdbdbdf2a0247e4ef6529 280 Gene3D G3DSA:3.40.50.12370 5 280 3.1E-33 T 12-10-2018 VAPA_2c04330 4218df3c3f7cdbdbdf2a0247e4ef6529 280 SUPERFAMILY SSF52402 157 279 7.37E-20 T 12-10-2018 VAPA_2c04330 4218df3c3f7cdbdbdf2a0247e4ef6529 280 SUPERFAMILY SSF52402 1 147 2.76E-13 T 12-10-2018 VAPA_1c38300 457e11c7ca64bd8258c52b301524b34e 353 Pfam PF01757 Acyltransferase family 16 321 2.4E-25 T 12-10-2018 IPR002656 Acyltransferase 3 GO:0016747 VAPA_1c25150 7b9cb6d45084e45d480a66dea607d517 281 Pfam PF01614 Bacterial transcriptional regulator 132 251 1.1E-30 T 12-10-2018 IPR014757 Transcription regulator IclR, C-terminal VAPA_1c25150 7b9cb6d45084e45d480a66dea607d517 281 SUPERFAMILY SSF55781 71 256 9.81E-44 T 12-10-2018 VAPA_1c25150 7b9cb6d45084e45d480a66dea607d517 281 Gene3D G3DSA:1.10.10.10 13 84 2.3E-20 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c25150 7b9cb6d45084e45d480a66dea607d517 281 Gene3D G3DSA:3.30.450.40 85 267 9.3E-51 T 12-10-2018 IPR029016 GAF-like domain superfamily VAPA_1c25150 7b9cb6d45084e45d480a66dea607d517 281 Pfam PF09339 IclR helix-turn-helix domain 17 65 1.2E-12 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 VAPA_1c25150 7b9cb6d45084e45d480a66dea607d517 281 SMART SM00346 14 103 2.4E-21 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 VAPA_1c25150 7b9cb6d45084e45d480a66dea607d517 281 SUPERFAMILY SSF46785 14 85 1.39E-15 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c18360 97b88e9f54d36906c92f164db0de2473 335 Pfam PF02653 Branched-chain amino acid transport system / permease component 45 308 2.2E-34 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 VAPA_1c49970 6797933033b28bf4155aaf8a8f5b9ff5 209 Pfam PF04471 Restriction endonuclease 34 143 2.6E-23 T 12-10-2018 IPR007560 Restriction endonuclease type IV, Mrr GO:0003677|GO:0004519|GO:0009307 VAPA_1c49970 6797933033b28bf4155aaf8a8f5b9ff5 209 SUPERFAMILY SSF52980 37 144 1.18E-15 T 12-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 VAPA_1c10870 34252d7ed619959b22230950da6ae2be 195 SUPERFAMILY SSF47413 9 73 1.39E-17 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 VAPA_1c10870 34252d7ed619959b22230950da6ae2be 195 Gene3D G3DSA:2.60.120.10 100 193 4.1E-9 T 12-10-2018 IPR014710 RmlC-like jelly roll fold VAPA_1c10870 34252d7ed619959b22230950da6ae2be 195 SUPERFAMILY SSF51182 56 188 3.45E-18 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily VAPA_1c10870 34252d7ed619959b22230950da6ae2be 195 Gene3D G3DSA:1.10.260.40 5 76 2.4E-19 T 12-10-2018 VAPA_1c10870 34252d7ed619959b22230950da6ae2be 195 SMART SM00530 15 70 4.9E-14 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 VAPA_1c10870 34252d7ed619959b22230950da6ae2be 195 Pfam PF13560 Helix-turn-helix domain 11 69 7.3E-14 T 12-10-2018 VAPA_1c38530 51e48cbbc4a01340fc4b7a8134796ca2 322 SUPERFAMILY SSF103481 54 154 1.31E-16 T 12-10-2018 VAPA_1c38530 51e48cbbc4a01340fc4b7a8134796ca2 322 SUPERFAMILY SSF103481 206 300 4.45E-16 T 12-10-2018 VAPA_1c38530 51e48cbbc4a01340fc4b7a8134796ca2 322 Pfam PF00892 EamA-like transporter family 167 300 8.1E-19 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 VAPA_1c38530 51e48cbbc4a01340fc4b7a8134796ca2 322 Pfam PF00892 EamA-like transporter family 24 150 4.6E-20 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 VAPA_1c52110 b60c73c8282274f1a951bb21269e24c9 816 Pfam PF01011 PQQ enzyme repeat 689 722 1.6E-4 T 12-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat VAPA_1c52110 b60c73c8282274f1a951bb21269e24c9 816 Pfam PF01011 PQQ enzyme repeat 466 494 2.1E-6 T 12-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat VAPA_1c52110 b60c73c8282274f1a951bb21269e24c9 816 Pfam PF01011 PQQ enzyme repeat 239 264 2.0E-5 T 12-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat VAPA_1c52110 b60c73c8282274f1a951bb21269e24c9 816 Pfam PF01011 PQQ enzyme repeat 745 779 6.5E-6 T 12-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat VAPA_1c52110 b60c73c8282274f1a951bb21269e24c9 816 SUPERFAMILY SSF50998 173 814 4.84E-147 T 12-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily VAPA_1c52110 b60c73c8282274f1a951bb21269e24c9 816 Gene3D G3DSA:2.140.10.10 170 580 1.3E-111 T 12-10-2018 VAPA_1c52110 b60c73c8282274f1a951bb21269e24c9 816 TIGRFAM TIGR03074 PQQ_membr_DH: membrane-bound PQQ-dependent dehydrogenase, glucose/quinate/shikimate family 18 814 0.0 T 12-10-2018 IPR017511 PQQ-dependent membrane bound dehydrogenase GO:0016021|GO:0016614|GO:0048038|GO:0055114 VAPA_1c52110 b60c73c8282274f1a951bb21269e24c9 816 SMART SM00564 736 769 0.028 T 12-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat VAPA_1c52110 b60c73c8282274f1a951bb21269e24c9 816 SMART SM00564 434 484 0.41 T 12-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat VAPA_1c52110 b60c73c8282274f1a951bb21269e24c9 816 SMART SM00564 232 263 0.69 T 12-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat VAPA_1c52110 b60c73c8282274f1a951bb21269e24c9 816 SMART SM00564 507 538 410.0 T 12-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat VAPA_1c52110 b60c73c8282274f1a951bb21269e24c9 816 SMART SM00564 364 406 11.0 T 12-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat VAPA_1c52110 b60c73c8282274f1a951bb21269e24c9 816 Gene3D G3DSA:2.140.10.10 581 815 1.3E-37 T 12-10-2018 VAPA_1c14370 bdd64876fc46660c8ba73445ceb0ae49 148 Pfam PF13456 Reverse transcriptase-like 10 130 3.3E-17 T 12-10-2018 IPR002156 Ribonuclease H domain GO:0003676|GO:0004523 VAPA_1c14370 bdd64876fc46660c8ba73445ceb0ae49 148 Gene3D G3DSA:3.30.420.10 5 135 5.0E-27 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 VAPA_1c14370 bdd64876fc46660c8ba73445ceb0ae49 148 SUPERFAMILY SSF53098 4 129 4.17E-25 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily VAPA_1c27830 81b0936945a6b43eeafa58ba6a653e0a 312 SUPERFAMILY SSF103481 46 148 3.4E-13 T 12-10-2018 VAPA_1c27830 81b0936945a6b43eeafa58ba6a653e0a 312 SUPERFAMILY SSF103481 197 300 1.09E-11 T 12-10-2018 VAPA_1c27830 81b0936945a6b43eeafa58ba6a653e0a 312 Pfam PF00892 EamA-like transporter family 16 145 9.5E-20 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 VAPA_1c27830 81b0936945a6b43eeafa58ba6a653e0a 312 Pfam PF00892 EamA-like transporter family 161 296 1.6E-16 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 VAPA_1c38790 4a2cee8d304de011fe5790314a82e485 194 Pfam PF04366 Las17-binding protein actin regulator 107 191 1.7E-13 T 12-10-2018 IPR007461 Ysc84 actin-binding domain VAPA_1c17290 3e97f2348a87ffc449bc43cba886acd3 113 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 10 101 4.7E-16 T 12-10-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family VAPA_1c17290 3e97f2348a87ffc449bc43cba886acd3 113 Gene3D G3DSA:3.30.2310.20 3 106 2.3E-20 T 12-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily VAPA_1c17290 3e97f2348a87ffc449bc43cba886acd3 113 SUPERFAMILY SSF143011 8 101 6.67E-8 T 12-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily VAPA_1c11050 830b7e84712ef3e0b74fc1a8c74353c8 305 SUPERFAMILY SSF51569 1 299 1.47E-66 T 12-10-2018 VAPA_1c11050 830b7e84712ef3e0b74fc1a8c74353c8 305 SMART SM01130 4 297 8.5E-62 T 12-10-2018 IPR002220 DapA-like GO:0016829 VAPA_1c11050 830b7e84712ef3e0b74fc1a8c74353c8 305 Pfam PF00701 Dihydrodipicolinate synthetase family 6 293 2.4E-30 T 12-10-2018 IPR002220 DapA-like GO:0016829 VAPA_1c11050 830b7e84712ef3e0b74fc1a8c74353c8 305 Gene3D G3DSA:3.20.20.70 1 305 1.4E-112 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 VAPA_1c11050 830b7e84712ef3e0b74fc1a8c74353c8 305 PIRSF PIRSF001365 1 303 9.4E-52 T 12-10-2018 IPR002220 DapA-like GO:0016829 VAPA_1c35590 f51b2f346dfcc190fb406e7a70519025 174 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 12 45 1.1E-4 T 12-10-2018 IPR001451 Hexapeptide repeat VAPA_1c35590 f51b2f346dfcc190fb406e7a70519025 174 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 88 122 4.6E-11 T 12-10-2018 IPR001451 Hexapeptide repeat VAPA_1c35590 f51b2f346dfcc190fb406e7a70519025 174 SUPERFAMILY SSF51161 6 170 1.39E-49 T 12-10-2018 IPR011004 Trimeric LpxA-like superfamily VAPA_1c35590 f51b2f346dfcc190fb406e7a70519025 174 Gene3D G3DSA:2.160.10.10 1 173 2.9E-66 T 12-10-2018 VAPA_1c29960 7c956a5cdcda9963e475546f48e2b146 117 Pfam PF03788 LrgA family 12 104 6.3E-26 T 12-10-2018 IPR005538 LrgA/CidA family GO:0016021 VAPA_1c31190 2054c3a87137ad057750469dea33b6fa 383 Gene3D G3DSA:3.20.20.70 13 289 1.7E-40 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 VAPA_1c31190 2054c3a87137ad057750469dea33b6fa 383 Pfam PF13394 4Fe-4S single cluster domain 21 72 7.5E-5 T 12-10-2018 VAPA_1c31190 2054c3a87137ad057750469dea33b6fa 383 TIGRFAM TIGR02109 PQQ_syn_pqqE: coenzyme PQQ biosynthesis enzyme PqqE 8 356 6.7E-153 T 12-10-2018 IPR011843 Coenzyme PQQ biosynthesis protein E, bacteria GO:0018189|GO:0051539 VAPA_1c31190 2054c3a87137ad057750469dea33b6fa 383 Pfam PF04055 Radical SAM superfamily 18 171 3.8E-21 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 VAPA_1c31190 2054c3a87137ad057750469dea33b6fa 383 TIGRFAM TIGR04085 rSAM_more_4Fe4S: radical SAM additional 4Fe4S-binding SPASM domain 248 334 2.2E-7 T 12-10-2018 IPR023885 4Fe4S-binding SPASM domain VAPA_1c31190 2054c3a87137ad057750469dea33b6fa 383 Pfam PF13186 Iron-sulfur cluster-binding domain 241 307 1.3E-7 T 12-10-2018 IPR023885 4Fe4S-binding SPASM domain VAPA_1c31190 2054c3a87137ad057750469dea33b6fa 383 SUPERFAMILY SSF102114 10 316 1.01E-68 T 12-10-2018 VAPA_1c31190 2054c3a87137ad057750469dea33b6fa 383 Hamap MF_00660 Coenzyme PQQ synthesis protein E [pqqE]. 1 378 182.046 T 12-10-2018 IPR011843 Coenzyme PQQ biosynthesis protein E, bacteria GO:0018189|GO:0051539 VAPA_1c31190 2054c3a87137ad057750469dea33b6fa 383 PIRSF PIRSF037420 3 354 1.1E-106 T 12-10-2018 IPR017200 Coenzyme PQQ synthesis protein E VAPA_1c15960 a4030842bc0cbcf4c491e5cb5fdafb16 387 Pfam PF13458 Periplasmic binding protein 30 346 6.8E-48 T 12-10-2018 IPR028081 Leucine-binding protein domain VAPA_1c15960 a4030842bc0cbcf4c491e5cb5fdafb16 387 Gene3D G3DSA:3.40.50.2300 144 382 6.0E-104 T 12-10-2018 VAPA_1c15960 a4030842bc0cbcf4c491e5cb5fdafb16 387 SUPERFAMILY SSF53822 29 385 6.64E-68 T 12-10-2018 IPR028082 Periplasmic binding protein-like I VAPA_1c15960 a4030842bc0cbcf4c491e5cb5fdafb16 387 Gene3D G3DSA:3.40.50.2300 31 371 6.0E-104 T 12-10-2018 VAPA_1c36850 5c599196d0e8041557d3798eabff8828 746 Pfam PF12805 FUSC-like inner membrane protein yccS 85 354 3.4E-30 T 12-10-2018 IPR032692 Integral membrane protein YccS, N-terminal VAPA_1c36850 5c599196d0e8041557d3798eabff8828 746 Pfam PF13515 Fusaric acid resistance protein-like 419 541 8.1E-17 T 12-10-2018 VAPA_1c04180 50fc130c86370ebaca1926a6f44fce2d 299 Gene3D G3DSA:3.40.190.10 90 290 7.5E-66 T 12-10-2018 VAPA_1c04180 50fc130c86370ebaca1926a6f44fce2d 299 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 65 4.1E-19 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c04180 50fc130c86370ebaca1926a6f44fce2d 299 SUPERFAMILY SSF46785 3 81 6.12E-21 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c04180 50fc130c86370ebaca1926a6f44fce2d 299 Gene3D G3DSA:1.10.10.10 1 83 4.1E-29 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c04180 50fc130c86370ebaca1926a6f44fce2d 299 SUPERFAMILY SSF53850 88 294 3.26E-40 T 12-10-2018 VAPA_1c04180 50fc130c86370ebaca1926a6f44fce2d 299 Gene3D G3DSA:3.40.190.10 168 266 7.5E-66 T 12-10-2018 VAPA_1c04180 50fc130c86370ebaca1926a6f44fce2d 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 32 42 6.6E-7 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c04180 50fc130c86370ebaca1926a6f44fce2d 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 53 6.6E-7 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c04180 50fc130c86370ebaca1926a6f44fce2d 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 21 32 6.6E-7 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c04180 50fc130c86370ebaca1926a6f44fce2d 299 Pfam PF03466 LysR substrate binding domain 93 294 3.1E-21 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_1c03330 4b5590d45581f761e1bebff92479d45b 233 SUPERFAMILY SSF52499 8 230 2.88E-59 T 12-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 VAPA_1c03330 4b5590d45581f761e1bebff92479d45b 233 Pfam PF00857 Isochorismatase family 27 220 2.3E-45 T 12-10-2018 IPR000868 Isochorismatase-like GO:0003824 VAPA_1c03330 4b5590d45581f761e1bebff92479d45b 233 Gene3D G3DSA:3.40.50.850 21 233 3.2E-62 T 12-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 VAPA_2c04260 e3416fb7adb3aabff25fad3f1c8c7bc7 181 Gene3D G3DSA:3.30.160.100 5 106 1.7E-14 T 12-10-2018 IPR036567 Ribosome hibernation promotion factor-like VAPA_2c04260 e3416fb7adb3aabff25fad3f1c8c7bc7 181 Gene3D G3DSA:2.40.50.140 112 174 3.6E-8 T 12-10-2018 VAPA_2c04260 e3416fb7adb3aabff25fad3f1c8c7bc7 181 SUPERFAMILY SSF69754 5 106 1.83E-18 T 12-10-2018 IPR036567 Ribosome hibernation promotion factor-like VAPA_2c04260 e3416fb7adb3aabff25fad3f1c8c7bc7 181 SUPERFAMILY SSF50249 112 174 2.45E-7 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold VAPA_2c04260 e3416fb7adb3aabff25fad3f1c8c7bc7 181 Pfam PF02482 Sigma 54 modulation protein / S30EA ribosomal protein 6 100 3.0E-14 T 12-10-2018 IPR003489 Ribosome hibernation promoting factor/RaiA GO:0044238 VAPA_1c08420 1a68c689d16f77511692eef8eaf7c694 295 SUPERFAMILY SSF103481 196 290 7.85E-12 T 12-10-2018 VAPA_1c08420 1a68c689d16f77511692eef8eaf7c694 295 SUPERFAMILY SSF103481 52 149 2.09E-6 T 12-10-2018 VAPA_1c08420 1a68c689d16f77511692eef8eaf7c694 295 Pfam PF00892 EamA-like transporter family 156 286 1.2E-10 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 VAPA_1c38100 18ddd548052cba7e4be0a3eab1ef85e7 291 SUPERFAMILY SSF161098 59 284 1.19E-44 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c38100 18ddd548052cba7e4be0a3eab1ef85e7 291 Gene3D G3DSA:1.10.3720.10 57 291 1.6E-49 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c38100 18ddd548052cba7e4be0a3eab1ef85e7 291 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 96 284 1.4E-14 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 VAPA_1c06700 a1ab25fe15bb9b4563e185ead79c4ecd 277 SUPERFAMILY SSF52499 57 260 2.62E-35 T 12-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 VAPA_1c06700 a1ab25fe15bb9b4563e185ead79c4ecd 277 Gene3D G3DSA:3.40.50.850 53 262 2.8E-35 T 12-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 VAPA_1c06700 a1ab25fe15bb9b4563e185ead79c4ecd 277 Pfam PF00857 Isochorismatase family 64 219 6.3E-16 T 12-10-2018 IPR000868 Isochorismatase-like GO:0003824 VAPA_1c24180 b7154d296406ea76a2d3f2a875550eb6 335 Gene3D G3DSA:3.40.190.10 32 301 2.5E-68 T 12-10-2018 VAPA_1c24180 b7154d296406ea76a2d3f2a875550eb6 335 SUPERFAMILY SSF53850 34 258 3.44E-31 T 12-10-2018 VAPA_1c24180 b7154d296406ea76a2d3f2a875550eb6 335 Pfam PF09084 NMT1/THI5 like 40 252 5.7E-54 T 12-10-2018 IPR015168 SsuA/THI5-like VAPA_1c24180 b7154d296406ea76a2d3f2a875550eb6 335 Gene3D G3DSA:3.40.190.10 112 213 2.5E-68 T 12-10-2018 VAPA_1c26120 d75a60081d232c1ab203d00c84a993b4 274 ProSitePatterns PS00680 Methionine aminopeptidase subfamily 1 signature. 171 189 - T 12-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 VAPA_1c26120 d75a60081d232c1ab203d00c84a993b4 274 Hamap MF_01974 Methionine aminopeptidase [map]. 3 259 40.257 T 12-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 VAPA_1c26120 d75a60081d232c1ab203d00c84a993b4 274 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 6 258 3.7E-88 T 12-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 VAPA_1c26120 d75a60081d232c1ab203d00c84a993b4 274 SUPERFAMILY SSF55920 3 257 3.53E-85 T 12-10-2018 IPR036005 Creatinase/aminopeptidase-like VAPA_1c26120 d75a60081d232c1ab203d00c84a993b4 274 PRINTS PR00599 Methionine aminopeptidase-1 signature 73 86 4.9E-22 T 12-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 VAPA_1c26120 d75a60081d232c1ab203d00c84a993b4 274 PRINTS PR00599 Methionine aminopeptidase-1 signature 196 208 4.9E-22 T 12-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 VAPA_1c26120 d75a60081d232c1ab203d00c84a993b4 274 PRINTS PR00599 Methionine aminopeptidase-1 signature 95 111 4.9E-22 T 12-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 VAPA_1c26120 d75a60081d232c1ab203d00c84a993b4 274 PRINTS PR00599 Methionine aminopeptidase-1 signature 165 177 4.9E-22 T 12-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 VAPA_1c26120 d75a60081d232c1ab203d00c84a993b4 274 Pfam PF00557 Metallopeptidase family M24 12 250 5.9E-55 T 12-10-2018 IPR000994 Peptidase M24 VAPA_1c26120 d75a60081d232c1ab203d00c84a993b4 274 Gene3D G3DSA:3.90.230.10 1 265 3.7E-103 T 12-10-2018 VAPA_1c41440 5586dcabe523a3399abdc81702f59ca0 206 Pfam PF06080 Protein of unknown function (DUF938) 6 204 3.2E-70 T 12-10-2018 IPR010342 Protein of unknown function DUF938 VAPA_1c41440 5586dcabe523a3399abdc81702f59ca0 206 SUPERFAMILY SSF53335 16 200 2.84E-27 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase VAPA_1c41440 5586dcabe523a3399abdc81702f59ca0 206 Gene3D G3DSA:3.40.50.150 5 203 3.9E-20 T 12-10-2018 VAPA_1c05630 7911e1f36fcc2047d1a47aad608e6297 164 Pfam PF12680 SnoaL-like domain 10 116 1.1E-12 T 12-10-2018 IPR037401 SnoaL-like domain VAPA_1c05630 7911e1f36fcc2047d1a47aad608e6297 164 Gene3D G3DSA:3.10.450.50 1 131 1.3E-18 T 12-10-2018 VAPA_1c05630 7911e1f36fcc2047d1a47aad608e6297 164 SUPERFAMILY SSF54427 5 140 6.59E-23 T 12-10-2018 IPR032710 NTF2-like domain superfamily VAPA_1c34030 f85763349f0c24c9e2c1275ab77b2d75 338 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 211 5.9E-21 T 12-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 VAPA_1c34030 f85763349f0c24c9e2c1275ab77b2d75 338 SUPERFAMILY SSF51735 1 326 5.11E-40 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c34030 f85763349f0c24c9e2c1275ab77b2d75 338 Gene3D G3DSA:3.90.25.10 185 322 4.9E-103 T 12-10-2018 VAPA_1c34030 f85763349f0c24c9e2c1275ab77b2d75 338 Gene3D G3DSA:3.40.50.720 8 312 4.9E-103 T 12-10-2018 VAPA_1c54380 549984c7acbbcc5a9cbe9d5f586596aa 308 SUPERFAMILY SSF103481 200 295 1.57E-11 T 12-10-2018 VAPA_1c54380 549984c7acbbcc5a9cbe9d5f586596aa 308 Pfam PF00892 EamA-like transporter family 159 287 3.5E-12 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 VAPA_1c54380 549984c7acbbcc5a9cbe9d5f586596aa 308 Pfam PF00892 EamA-like transporter family 19 150 3.2E-14 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 VAPA_1c54380 549984c7acbbcc5a9cbe9d5f586596aa 308 SUPERFAMILY SSF103481 60 153 7.45E-12 T 12-10-2018 VAPA_2c01900 5f9dad8a54e941427bbc69a72a894f3c 415 SUPERFAMILY SSF53756 1 407 6.28E-83 T 12-10-2018 VAPA_2c01900 5f9dad8a54e941427bbc69a72a894f3c 415 Gene3D G3DSA:3.40.50.2000 226 394 1.2E-107 T 12-10-2018 VAPA_2c01900 5f9dad8a54e941427bbc69a72a894f3c 415 Gene3D G3DSA:3.40.50.2000 2 225 1.2E-107 T 12-10-2018 VAPA_2c07280 e042c349454bc4b10ef2df9775806cb2 252 SUPERFAMILY SSF161098 23 211 1.27E-41 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_2c07280 e042c349454bc4b10ef2df9775806cb2 252 Gene3D G3DSA:1.10.3720.10 19 229 2.8E-52 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_2c07280 e042c349454bc4b10ef2df9775806cb2 252 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 27 119 4.6E-25 T 12-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 VAPA_2c07280 e042c349454bc4b10ef2df9775806cb2 252 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 43 226 2.3E-19 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 VAPA_1c10300 9e5c780e3964635bf86d59921921bc93 261 SUPERFAMILY SSF51735 14 252 8.18E-52 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c10300 9e5c780e3964635bf86d59921921bc93 261 Gene3D G3DSA:3.40.50.720 12 259 2.0E-52 T 12-10-2018 VAPA_1c10300 9e5c780e3964635bf86d59921921bc93 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 164 183 1.2E-18 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c10300 9e5c780e3964635bf86d59921921bc93 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 90 101 1.2E-18 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c10300 9e5c780e3964635bf86d59921921bc93 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 184 201 1.2E-18 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c10300 9e5c780e3964635bf86d59921921bc93 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 215 235 1.2E-18 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c10300 9e5c780e3964635bf86d59921921bc93 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 15 32 1.2E-18 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c10300 9e5c780e3964635bf86d59921921bc93 261 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 20 250 1.2E-32 T 12-10-2018 VAPA_2c03670 50e063ebf93f6f7cbbb9a8e382f5b40f 421 Pfam PF13458 Periplasmic binding protein 33 395 1.8E-59 T 12-10-2018 IPR028081 Leucine-binding protein domain VAPA_2c03670 50e063ebf93f6f7cbbb9a8e382f5b40f 421 Gene3D G3DSA:3.40.50.2300 158 297 7.4E-78 T 12-10-2018 VAPA_2c03670 50e063ebf93f6f7cbbb9a8e382f5b40f 421 SUPERFAMILY SSF53822 33 404 1.18E-73 T 12-10-2018 IPR028082 Periplasmic binding protein-like I VAPA_2c03670 50e063ebf93f6f7cbbb9a8e382f5b40f 421 Gene3D G3DSA:3.40.50.2300 41 362 7.4E-78 T 12-10-2018 VAPA_1c41160 0d842725dac0c77ecfbc0e577102c7f2 360 Pfam PF00355 Rieske [2Fe-2S] domain 13 99 9.7E-17 T 12-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 VAPA_1c41160 0d842725dac0c77ecfbc0e577102c7f2 360 Gene3D G3DSA:2.102.10.10 8 143 2.5E-30 T 12-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 VAPA_1c41160 0d842725dac0c77ecfbc0e577102c7f2 360 Gene3D G3DSA:3.30.530.90 144 348 4.0E-10 T 12-10-2018 VAPA_1c41160 0d842725dac0c77ecfbc0e577102c7f2 360 SUPERFAMILY SSF55961 129 344 9.16E-33 T 12-10-2018 VAPA_1c41160 0d842725dac0c77ecfbc0e577102c7f2 360 SUPERFAMILY SSF50022 6 128 8.25E-30 T 12-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 VAPA_2c12700 573ad20ba1c90b96ab2df4a892520070 456 TIGRFAM TIGR03071 couple_hipA: HipA N-terminal domain 19 112 3.2E-13 T 12-10-2018 IPR017508 HipA, N-terminal subdomain 1 VAPA_2c12700 573ad20ba1c90b96ab2df4a892520070 456 Pfam PF07804 HipA-like C-terminal domain 156 408 9.5E-43 T 12-10-2018 IPR012893 HipA-like, C-terminal VAPA_2c12700 573ad20ba1c90b96ab2df4a892520070 456 Pfam PF13657 HipA N-terminal domain 17 112 5.2E-16 T 12-10-2018 IPR017508 HipA, N-terminal subdomain 1 VAPA_1c28640 0d7230873b82e2521c8e028a32e26533 262 SUPERFAMILY SSF53335 36 242 2.05E-37 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase VAPA_1c28640 0d7230873b82e2521c8e028a32e26533 262 ProSitePatterns PS01184 ubiE/COQ5 methyltransferase family signature 2. 160 174 - T 12-10-2018 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 VAPA_1c28640 0d7230873b82e2521c8e028a32e26533 262 Gene3D G3DSA:3.40.50.150 41 254 3.5E-43 T 12-10-2018 VAPA_1c28640 0d7230873b82e2521c8e028a32e26533 262 Pfam PF01209 ubiE/COQ5 methyltransferase family 35 247 6.4E-30 T 12-10-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 VAPA_1c05110 294cf04990029a39c144248b39298234 421 Pfam PF03594 Benzoate membrane transport protein 6 382 6.4E-136 T 12-10-2018 IPR004711 Benzoate transporter GO:0016021|GO:0042919|GO:0042925 VAPA_1c05110 294cf04990029a39c144248b39298234 421 TIGRFAM TIGR00843 benE: benzoate transporter 11 382 8.3E-120 T 12-10-2018 IPR004711 Benzoate transporter GO:0016021|GO:0042919|GO:0042925 VAPA_2c11390 a38c3a60e5d4025100cb1f1601a343b7 362 Pfam PF02653 Branched-chain amino acid transport system / permease component 40 309 8.9E-33 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 VAPA_1c54520 ad725432dfa2c6937fc9d74e984f7a43 226 Gene3D G3DSA:1.10.3720.10 4 220 2.9E-50 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c54520 ad725432dfa2c6937fc9d74e984f7a43 226 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 35 217 2.0E-18 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 VAPA_1c54520 ad725432dfa2c6937fc9d74e984f7a43 226 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 15 112 6.6E-26 T 12-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 VAPA_1c54520 ad725432dfa2c6937fc9d74e984f7a43 226 SUPERFAMILY SSF161098 15 203 6.28E-42 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c26490 25cfff490ab65d573b2eebe281686fe8 231 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 35 49 3.7E-6 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_1c26490 25cfff490ab65d573b2eebe281686fe8 231 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 49 65 3.7E-6 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_1c26490 25cfff490ab65d573b2eebe281686fe8 231 Gene3D G3DSA:1.10.10.10 9 75 7.2E-22 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c26490 25cfff490ab65d573b2eebe281686fe8 231 Gene3D G3DSA:1.20.120.530 79 222 7.7E-30 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal VAPA_1c26490 25cfff490ab65d573b2eebe281686fe8 231 SMART SM00895 85 209 1.3E-20 T 12-10-2018 IPR011711 GntR, C-terminal VAPA_1c26490 25cfff490ab65d573b2eebe281686fe8 231 Pfam PF00392 Bacterial regulatory proteins, gntR family 14 73 7.6E-18 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_1c26490 25cfff490ab65d573b2eebe281686fe8 231 SMART SM00345 17 75 7.4E-14 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_1c26490 25cfff490ab65d573b2eebe281686fe8 231 Pfam PF07729 FCD domain 86 208 1.1E-28 T 12-10-2018 IPR011711 GntR, C-terminal VAPA_1c26490 25cfff490ab65d573b2eebe281686fe8 231 SUPERFAMILY SSF48008 82 218 6.54E-27 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal VAPA_1c26490 25cfff490ab65d573b2eebe281686fe8 231 SUPERFAMILY SSF46785 9 79 2.9E-19 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c53380 1455ee53cde9922bbee47240b3deeea4 440 SUPERFAMILY SSF103473 15 438 1.1E-86 T 12-10-2018 IPR036259 MFS transporter superfamily VAPA_1c53380 1455ee53cde9922bbee47240b3deeea4 440 Gene3D G3DSA:1.20.1250.20 14 437 1.9E-85 T 12-10-2018 VAPA_1c53380 1455ee53cde9922bbee47240b3deeea4 440 Pfam PF07690 Major Facilitator Superfamily 35 399 6.0E-47 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 VAPA_1c15630 672675ee30d3f701b67bf014f194a82e 148 Pfam PF05154 TM2 domain 2 61 5.7E-7 T 12-10-2018 IPR007829 TM2 domain VAPA_1c01240 29e4dfd645076168dda9efc6f92cd4df 241 Gene3D G3DSA:3.40.50.12500 5 240 2.8E-60 T 12-10-2018 VAPA_1c01240 29e4dfd645076168dda9efc6f92cd4df 241 PIRSF PIRSF015736 1 240 9.7E-59 T 12-10-2018 IPR026286 Maleate isomerase/Arylmalonate decarboxylase VAPA_2c06080 16ecb25d423357b712e67aea8edb2f41 170 SUPERFAMILY SSF55874 49 166 6.94E-30 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_2c06080 16ecb25d423357b712e67aea8edb2f41 170 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 63 166 6.6E-15 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase VAPA_2c06080 16ecb25d423357b712e67aea8edb2f41 170 PRINTS PR00344 Bacterial sensor protein C-terminal signature 152 165 5.8E-12 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_2c06080 16ecb25d423357b712e67aea8edb2f41 170 PRINTS PR00344 Bacterial sensor protein C-terminal signature 115 125 5.8E-12 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_2c06080 16ecb25d423357b712e67aea8edb2f41 170 PRINTS PR00344 Bacterial sensor protein C-terminal signature 128 146 5.8E-12 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_2c06080 16ecb25d423357b712e67aea8edb2f41 170 PRINTS PR00344 Bacterial sensor protein C-terminal signature 97 111 5.8E-12 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_2c06080 16ecb25d423357b712e67aea8edb2f41 170 SMART SM00387 60 168 1.2E-19 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase VAPA_2c06080 16ecb25d423357b712e67aea8edb2f41 170 Gene3D G3DSA:3.30.565.10 40 168 4.3E-28 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_2c07490 b70286bb443e42e5e3a06261768a304c 309 Pfam PF08843 Nucleotidyl transferase AbiEii toxin, Type IV TA system 10 278 4.2E-46 T 12-10-2018 IPR014942 Nucleotidyl transferase AbiEii toxin, Type IV TA system VAPA_1c31940 8a94385b012c5835925425eb1e39bc96 139 Pfam PF07681 DoxX 16 96 1.9E-20 T 12-10-2018 IPR032808 DoxX family VAPA_1c11320 00960914d637e57a1c9d8ffe206599c2 227 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 10 31 2.3E-8 T 12-10-2018 IPR012902 Prokaryotic N-terminal methylation site VAPA_1c11320 00960914d637e57a1c9d8ffe206599c2 227 SUPERFAMILY SSF54523 13 122 4.6E-9 T 12-10-2018 VAPA_1c11320 00960914d637e57a1c9d8ffe206599c2 227 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 11 31 - T 12-10-2018 IPR012902 Prokaryotic N-terminal methylation site VAPA_1c11320 00960914d637e57a1c9d8ffe206599c2 227 Pfam PF07963 Prokaryotic N-terminal methylation motif 7 32 1.6E-9 T 12-10-2018 IPR012902 Prokaryotic N-terminal methylation site VAPA_1c11320 00960914d637e57a1c9d8ffe206599c2 227 Gene3D G3DSA:3.30.700.10 13 72 1.3E-6 T 12-10-2018 VAPA_1c19810 645d6984e473b55536d3291e7404b36c 177 SUPERFAMILY SSF50199 15 165 3.4E-28 T 12-10-2018 VAPA_1c19810 645d6984e473b55536d3291e7404b36c 177 Gene3D G3DSA:2.40.50.90 21 171 3.8E-24 T 12-10-2018 IPR035437 SNase-like, OB-fold superfamily VAPA_1c19810 645d6984e473b55536d3291e7404b36c 177 Pfam PF00565 Staphylococcal nuclease homologue 48 157 6.8E-17 T 12-10-2018 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold Reactome: R-HSA-6802952 VAPA_1c19810 645d6984e473b55536d3291e7404b36c 177 SMART SM00318 19 158 1.8E-23 T 12-10-2018 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold Reactome: R-HSA-6802952 VAPA_1c48080 0d6c87278baf0233fea416fd87b263a2 206 Pfam PF13376 Bacteriocin-protection, YdeI or OmpD-Associated 143 200 1.6E-22 T 12-10-2018 VAPA_1c37450 846d036bab82654708aeba8dce480506 541 TIGRFAM TIGR02231 TIGR02231: conserved hypothetical protein 36 538 3.7E-78 T 12-10-2018 IPR011935 Conserved hypothetical protein CHP02231 VAPA_1c37450 846d036bab82654708aeba8dce480506 541 Pfam PF13600 N-terminal domain of unknown function (DUF4140) 40 128 1.6E-14 T 12-10-2018 IPR025554 Domain of unknown function DUF4140 VAPA_1c37450 846d036bab82654708aeba8dce480506 541 Pfam PF13598 Domain of unknown function (DUF4139) 222 534 1.7E-48 T 12-10-2018 IPR037291 Domain of unknown function DUF4139 VAPA_1c15340 5225d40cfbb1e6593080e7193299b782 152 Gene3D G3DSA:3.60.21.10 2 149 5.9E-26 T 12-10-2018 IPR029052 Metallo-dependent phosphatase-like VAPA_1c15340 5225d40cfbb1e6593080e7193299b782 152 SUPERFAMILY SSF56300 3 151 1.41E-34 T 12-10-2018 VAPA_1c15340 5225d40cfbb1e6593080e7193299b782 152 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 3 135 6.8E-29 T 12-10-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 VAPA_1c15340 5225d40cfbb1e6593080e7193299b782 152 TIGRFAM TIGR00040 yfcE: phosphodiesterase, MJ0936 family 3 146 1.8E-24 T 12-10-2018 IPR000979 Phosphodiesterase MJ0936/Vps29 Reactome: R-HSA-3238698 VAPA_1c15790 b89f13ed0f33f502c2ea9255ecde568e 267 Gene3D G3DSA:3.40.50.1820 7 263 1.4E-47 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c15790 b89f13ed0f33f502c2ea9255ecde568e 267 Pfam PF00561 alpha/beta hydrolase fold 26 238 4.2E-14 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 VAPA_1c15790 b89f13ed0f33f502c2ea9255ecde568e 267 PRINTS PR00111 Alpha/beta hydrolase fold signature 95 108 1.6E-9 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 VAPA_1c15790 b89f13ed0f33f502c2ea9255ecde568e 267 PRINTS PR00111 Alpha/beta hydrolase fold signature 51 66 1.6E-9 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 VAPA_1c15790 b89f13ed0f33f502c2ea9255ecde568e 267 PRINTS PR00111 Alpha/beta hydrolase fold signature 109 122 1.6E-9 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 VAPA_1c15790 b89f13ed0f33f502c2ea9255ecde568e 267 SUPERFAMILY SSF53474 5 263 2.44E-45 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_2c01220 2022dcad15ef85f1403f35bf7adecc68 237 SUPERFAMILY SSF53448 6 197 3.28E-20 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases VAPA_2c01220 2022dcad15ef85f1403f35bf7adecc68 237 Gene3D G3DSA:3.90.550.10 1 168 5.1E-15 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases VAPA_2c01220 2022dcad15ef85f1403f35bf7adecc68 237 Pfam PF00535 Glycosyl transferase family 2 15 132 4.2E-9 T 12-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 VAPA_1c48200 8a6a7ddc262c238ae838080431001933 146 Pfam PF02580 D-Tyr-tRNA(Tyr) deacylase 2 143 3.4E-53 T 12-10-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 VAPA_1c48200 8a6a7ddc262c238ae838080431001933 146 SUPERFAMILY SSF69500 1 144 1.7E-54 T 12-10-2018 IPR023509 D-aminoacyl-tRNA deacylase-like superfamily VAPA_1c48200 8a6a7ddc262c238ae838080431001933 146 Gene3D G3DSA:3.50.80.10 1 145 3.8E-55 T 12-10-2018 IPR023509 D-aminoacyl-tRNA deacylase-like superfamily VAPA_1c48200 8a6a7ddc262c238ae838080431001933 146 Hamap MF_00518 D-aminoacyl-tRNA deacylase [dtd]. 1 145 33.871 T 12-10-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 VAPA_1c48200 8a6a7ddc262c238ae838080431001933 146 TIGRFAM TIGR00256 TIGR00256: D-tyrosyl-tRNA(Tyr) deacylase 1 144 3.3E-51 T 12-10-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 VAPA_1c34190 eeebb018bcd287b01d82bd463a46a1bc 530 Pfam PF08811 Protein of unknown function (DUF1800) 53 528 9.4E-137 T 12-10-2018 IPR014917 Protein of unknown function DUF1800 VAPA_1c33400 5c6c43a0945eb021c1253b67366b8d0c 213 SUPERFAMILY SSF53254 33 199 3.93E-36 T 12-10-2018 IPR029033 Histidine phosphatase superfamily VAPA_1c33400 5c6c43a0945eb021c1253b67366b8d0c 213 SMART SM00855 32 169 1.2E-17 T 12-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 VAPA_1c33400 5c6c43a0945eb021c1253b67366b8d0c 213 Gene3D G3DSA:3.40.50.1240 30 203 9.3E-39 T 12-10-2018 IPR029033 Histidine phosphatase superfamily VAPA_1c33400 5c6c43a0945eb021c1253b67366b8d0c 213 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 33 178 1.1E-31 T 12-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 VAPA_1c20120 c77284c7e4354c70a913c7138d0d4e33 193 SUPERFAMILY SSF88946 20 103 3.92E-14 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 VAPA_1c20120 c77284c7e4354c70a913c7138d0d4e33 193 SUPERFAMILY SSF88659 105 168 1.03E-5 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like VAPA_1c20120 c77284c7e4354c70a913c7138d0d4e33 193 Pfam PF04542 Sigma-70 region 2 22 87 2.2E-10 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 VAPA_1c20120 c77284c7e4354c70a913c7138d0d4e33 193 Gene3D G3DSA:1.10.10.10 89 171 1.2E-7 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c20120 c77284c7e4354c70a913c7138d0d4e33 193 Gene3D G3DSA:1.10.1740.10 3 84 1.2E-11 T 12-10-2018 VAPA_1c50400 38741b883ab72eb29925cdf16dbe3678 335 Pfam PF09084 NMT1/THI5 like 51 269 8.8E-12 T 12-10-2018 IPR015168 SsuA/THI5-like VAPA_1c50400 38741b883ab72eb29925cdf16dbe3678 335 SUPERFAMILY SSF53850 39 268 1.18E-25 T 12-10-2018 VAPA_1c50400 38741b883ab72eb29925cdf16dbe3678 335 Gene3D G3DSA:3.40.190.10 149 334 8.5E-18 T 12-10-2018 VAPA_1c50400 38741b883ab72eb29925cdf16dbe3678 335 Gene3D G3DSA:3.40.190.10 34 147 3.2E-11 T 12-10-2018 VAPA_1c39680 6b7d42ae252d1dc841aa29f8f4330787 558 SUPERFAMILY SSF51556 62 514 5.01E-30 T 12-10-2018 IPR032466 Metal-dependent hydrolase VAPA_1c39680 6b7d42ae252d1dc841aa29f8f4330787 558 Gene3D G3DSA:3.10.310.70 85 220 1.1E-95 T 12-10-2018 VAPA_1c39680 6b7d42ae252d1dc841aa29f8f4330787 558 SUPERFAMILY SSF51338 14 553 1.24E-11 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 VAPA_1c39680 6b7d42ae252d1dc841aa29f8f4330787 558 Gene3D G3DSA:2.30.40.10 13 531 1.1E-95 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 VAPA_1c39680 6b7d42ae252d1dc841aa29f8f4330787 558 Pfam PF07969 Amidohydrolase family 57 552 7.7E-66 T 12-10-2018 IPR013108 Amidohydrolase 3 VAPA_1c39680 6b7d42ae252d1dc841aa29f8f4330787 558 Gene3D G3DSA:3.20.20.140 63 513 1.1E-95 T 12-10-2018 VAPA_2c03120 62524c05cc6c05f99ca6a66434a4ea06 302 Pfam PF04909 Amidohydrolase 29 293 7.4E-34 T 12-10-2018 IPR006680 Amidohydrolase-related GO:0016787 VAPA_2c03120 62524c05cc6c05f99ca6a66434a4ea06 302 Gene3D G3DSA:3.20.20.140 14 295 1.3E-76 T 12-10-2018 VAPA_2c03120 62524c05cc6c05f99ca6a66434a4ea06 302 SUPERFAMILY SSF51556 25 294 3.09E-68 T 12-10-2018 IPR032466 Metal-dependent hydrolase VAPA_1c45600 301ef48e8180594a5f48624b40866f73 293 Pfam PF00510 Cytochrome c oxidase subunit III 12 292 9.0E-55 T 12-10-2018 IPR000298 Cytochrome c oxidase subunit III-like GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 VAPA_1c45600 301ef48e8180594a5f48624b40866f73 293 Gene3D G3DSA:1.20.120.80 76 293 6.5E-67 T 12-10-2018 IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle GO:0004129|GO:0016020|GO:0022904 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 VAPA_1c45600 301ef48e8180594a5f48624b40866f73 293 Gene3D G3DSA:1.10.287.70 4 75 3.4E-12 T 12-10-2018 VAPA_1c45600 301ef48e8180594a5f48624b40866f73 293 SUPERFAMILY SSF81452 9 293 5.36E-77 T 12-10-2018 IPR035973 Cytochrome c oxidase subunit III-like superfamily GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 VAPA_1c03560 7e6a1880f0dda005991a04a71f527509 248 Gene3D G3DSA:3.30.1600.10 40 167 1.8E-63 T 12-10-2018 IPR026591 Sirtuin, catalytic core small domain superfamily VAPA_1c03560 7e6a1880f0dda005991a04a71f527509 248 SUPERFAMILY SSF52467 11 245 1.54E-65 T 12-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily VAPA_1c03560 7e6a1880f0dda005991a04a71f527509 248 Gene3D G3DSA:3.40.50.1220 23 242 1.8E-63 T 12-10-2018 VAPA_1c03560 7e6a1880f0dda005991a04a71f527509 248 Pfam PF02146 Sir2 family 31 197 5.3E-36 T 12-10-2018 IPR003000 Sirtuin family GO:0070403 VAPA_2c12750 acba428ff8763b6d30e2d2faca07cc6e 189 Pfam PF01609 Transposase DDE domain 41 179 7.9E-18 T 12-10-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 VAPA_2c11970 acba428ff8763b6d30e2d2faca07cc6e 189 Pfam PF01609 Transposase DDE domain 41 179 7.9E-18 T 12-10-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 VAPA_2c00840 4f16a6bbc5d97dc117cdd092568625fa 188 Gene3D G3DSA:3.40.1580.10 12 155 1.2E-7 T 12-10-2018 IPR037883 Knr4/Smi1-like domain superfamily VAPA_2c00840 4f16a6bbc5d97dc117cdd092568625fa 188 SUPERFAMILY SSF160631 16 151 1.44E-8 T 12-10-2018 VAPA_1c03850 3ddb9a9bf92b8192b7616ee81c1f3273 77 ProDom PD056452 UNCHARACTERIZED BACTERIA SIMILAR YPEB CYTOPLASMIC VCA0163 PRODUCT STM2426 GENE YPO2988 14 70 1.0E-22 T 12-10-2018 IPR024530 Putative quorum-sensing-regulated virulence factor VAPA_1c03850 3ddb9a9bf92b8192b7616ee81c1f3273 77 Pfam PF12843 Putative quorum-sensing-regulated virulence factor 3 67 8.0E-30 T 12-10-2018 IPR024530 Putative quorum-sensing-regulated virulence factor VAPA_2c08260 71b3650917dd795824ca34c3b87dbfcf 358 Pfam PF01467 Cytidylyltransferase-like 12 76 2.1E-6 T 12-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 VAPA_2c08260 71b3650917dd795824ca34c3b87dbfcf 358 Gene3D G3DSA:3.40.50.620 2 203 2.2E-52 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold VAPA_2c08260 71b3650917dd795824ca34c3b87dbfcf 358 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 10 69 1.5E-8 T 12-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 VAPA_2c08260 71b3650917dd795824ca34c3b87dbfcf 358 SUPERFAMILY SSF55811 205 346 3.52E-29 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 VAPA_2c08260 71b3650917dd795824ca34c3b87dbfcf 358 Gene3D G3DSA:3.90.79.10 205 346 2.1E-39 T 12-10-2018 VAPA_2c08260 71b3650917dd795824ca34c3b87dbfcf 358 SUPERFAMILY SSF52374 10 149 3.97E-17 T 12-10-2018 VAPA_2c08260 71b3650917dd795824ca34c3b87dbfcf 358 Pfam PF00293 NUDIX domain 216 339 2.7E-18 T 12-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 VAPA_1c17650 fde3e0bfb2b45ecd6f5200e698716fe9 329 SUPERFAMILY SSF53850 116 290 8.22E-10 T 12-10-2018 VAPA_1c17650 fde3e0bfb2b45ecd6f5200e698716fe9 329 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 52 324 3.8E-78 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c17650 fde3e0bfb2b45ecd6f5200e698716fe9 329 Gene3D G3DSA:3.40.190.150 33 319 1.7E-108 T 12-10-2018 VAPA_1c17650 fde3e0bfb2b45ecd6f5200e698716fe9 329 Gene3D G3DSA:3.40.190.10 131 254 1.7E-108 T 12-10-2018 VAPA_1c17650 fde3e0bfb2b45ecd6f5200e698716fe9 329 PIRSF PIRSF017082 1 329 3.0E-84 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c01520 b2a785da4a49eb52902a1db28619d485 229 SMART SM00382 26 208 7.5E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c01520 b2a785da4a49eb52902a1db28619d485 229 SUPERFAMILY SSF52540 2 216 3.07E-55 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c01520 b2a785da4a49eb52902a1db28619d485 229 ProSitePatterns PS00211 ABC transporters family signature. 131 145 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_1c01520 b2a785da4a49eb52902a1db28619d485 229 Pfam PF00005 ABC transporter 18 158 1.6E-29 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c01520 b2a785da4a49eb52902a1db28619d485 229 Gene3D G3DSA:3.40.50.300 1 228 1.1E-55 T 12-10-2018 VAPA_1c01520 b2a785da4a49eb52902a1db28619d485 229 TIGRFAM TIGR03410 urea_trans_UrtE: urea ABC transporter, ATP-binding protein UrtE 2 229 7.4E-98 T 12-10-2018 IPR017780 ABC transporter, urea, ATP-binding protein, UrtE VAPA_1c44040 761d88cbb9e21a7294a0cdfabaeaeeae 75 SUPERFAMILY SSF89447 4 65 2.09E-12 T 12-10-2018 IPR037914 SpoVT-AbrB domain superfamily VAPA_1c44040 761d88cbb9e21a7294a0cdfabaeaeeae 75 TIGRFAM TIGR02609 doc_partner: putative addiction module antidote 4 75 7.5E-24 T 12-10-2018 IPR013432 Putative addiction module antidote VAPA_1c44040 761d88cbb9e21a7294a0cdfabaeaeeae 75 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 8 50 1.7E-6 T 12-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 VAPA_1c44040 761d88cbb9e21a7294a0cdfabaeaeeae 75 SMART SM00966 7 53 7.9E-5 T 12-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 VAPA_1c44040 761d88cbb9e21a7294a0cdfabaeaeeae 75 Gene3D G3DSA:2.10.260.10 1 73 7.5E-7 T 12-10-2018 VAPA_1c00550 1cd02c9be70f4b6de72b7cd4bb76540e 172 SMART SM01118 2 171 7.7E-12 T 12-10-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 VAPA_1c00550 1cd02c9be70f4b6de72b7cd4bb76540e 172 Pfam PF01928 CYTH domain 3 165 1.4E-15 T 12-10-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 VAPA_1c00550 1cd02c9be70f4b6de72b7cd4bb76540e 172 Gene3D G3DSA:2.40.320.10 1 172 3.9E-30 T 12-10-2018 VAPA_1c00550 1cd02c9be70f4b6de72b7cd4bb76540e 172 SUPERFAMILY SSF55154 3 169 4.41E-31 T 12-10-2018 IPR033469 CYTH-like domain superfamily Reactome: R-HSA-196819 VAPA_1c26870 d0537fc9035dce0c4f536866882dc1e7 375 SUPERFAMILY SSF141571 10 152 1.14E-31 T 12-10-2018 VAPA_1c26870 d0537fc9035dce0c4f536866882dc1e7 375 SUPERFAMILY SSF141571 158 326 8.14E-35 T 12-10-2018 VAPA_1c26870 d0537fc9035dce0c4f536866882dc1e7 375 Pfam PF00805 Pentapeptide repeats (8 copies) 290 319 1.4E-6 T 12-10-2018 IPR001646 Pentapeptide repeat VAPA_1c26870 d0537fc9035dce0c4f536866882dc1e7 375 Gene3D G3DSA:2.160.20.100 152 249 6.6E-19 T 12-10-2018 VAPA_1c26870 d0537fc9035dce0c4f536866882dc1e7 375 Gene3D G3DSA:2.160.20.100 4 151 1.5E-31 T 12-10-2018 VAPA_1c26870 d0537fc9035dce0c4f536866882dc1e7 375 Pfam PF13599 Pentapeptide repeats (9 copies) 115 186 7.6E-9 T 12-10-2018 IPR001646 Pentapeptide repeat VAPA_1c26870 d0537fc9035dce0c4f536866882dc1e7 375 Pfam PF13599 Pentapeptide repeats (9 copies) 39 108 1.1E-12 T 12-10-2018 IPR001646 Pentapeptide repeat VAPA_1c26870 d0537fc9035dce0c4f536866882dc1e7 375 Pfam PF13599 Pentapeptide repeats (9 copies) 200 276 2.9E-9 T 12-10-2018 IPR001646 Pentapeptide repeat VAPA_1c26870 d0537fc9035dce0c4f536866882dc1e7 375 Gene3D G3DSA:2.160.20.100 250 331 3.7E-12 T 12-10-2018 VAPA_2c07840 a60a3d60c6e93fb5291d0bc4ff2758bf 280 Gene3D G3DSA:3.20.20.150 3 280 7.7E-82 T 12-10-2018 VAPA_2c07840 a60a3d60c6e93fb5291d0bc4ff2758bf 280 Hamap MF_00697 UPF0276 protein . 7 279 43.51 T 12-10-2018 IPR007801 Uncharacterised protein family UPF0276 VAPA_2c07840 a60a3d60c6e93fb5291d0bc4ff2758bf 280 SUPERFAMILY SSF51658 30 252 3.11E-6 T 12-10-2018 IPR036237 Xylose isomerase-like superfamily VAPA_2c07840 a60a3d60c6e93fb5291d0bc4ff2758bf 280 Pfam PF05114 Protein of unknown function (DUF692) 7 269 9.4E-97 T 12-10-2018 IPR007801 Uncharacterised protein family UPF0276 VAPA_2c02210 8fbd801aed432702919884ba2d73a98b 313 SUPERFAMILY SSF53850 99 308 2.71E-15 T 12-10-2018 VAPA_2c02210 8fbd801aed432702919884ba2d73a98b 313 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 10 69 2.7E-19 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_2c02210 8fbd801aed432702919884ba2d73a98b 313 Gene3D G3DSA:3.40.190.10 160 293 6.0E-8 T 12-10-2018 VAPA_2c02210 8fbd801aed432702919884ba2d73a98b 313 SUPERFAMILY SSF46785 8 90 7.26E-20 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_2c02210 8fbd801aed432702919884ba2d73a98b 313 Pfam PF03466 LysR substrate binding domain 98 307 2.6E-17 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_2c02210 8fbd801aed432702919884ba2d73a98b 313 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 36 46 6.3E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_2c02210 8fbd801aed432702919884ba2d73a98b 313 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 25 36 6.3E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_2c02210 8fbd801aed432702919884ba2d73a98b 313 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 46 57 6.3E-8 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_2c02210 8fbd801aed432702919884ba2d73a98b 313 Gene3D G3DSA:3.40.190.10 178 281 6.0E-8 T 12-10-2018 VAPA_2c02210 8fbd801aed432702919884ba2d73a98b 313 Gene3D G3DSA:1.10.10.10 8 94 1.4E-22 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_2c05020 28e1a7ed127514e8b15646cebedcacb2 226 SUPERFAMILY SSF55874 68 219 4.98E-26 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_2c05020 28e1a7ed127514e8b15646cebedcacb2 226 PRINTS PR00344 Bacterial sensor protein C-terminal signature 168 178 2.6E-9 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_2c05020 28e1a7ed127514e8b15646cebedcacb2 226 PRINTS PR00344 Bacterial sensor protein C-terminal signature 181 199 2.6E-9 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_2c05020 28e1a7ed127514e8b15646cebedcacb2 226 PRINTS PR00344 Bacterial sensor protein C-terminal signature 205 218 2.6E-9 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_2c05020 28e1a7ed127514e8b15646cebedcacb2 226 PRINTS PR00344 Bacterial sensor protein C-terminal signature 150 164 2.6E-9 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 VAPA_2c05020 28e1a7ed127514e8b15646cebedcacb2 226 SMART SM00387 110 221 2.9E-13 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase VAPA_2c05020 28e1a7ed127514e8b15646cebedcacb2 226 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 113 219 1.9E-9 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase VAPA_2c05020 28e1a7ed127514e8b15646cebedcacb2 226 Gene3D G3DSA:3.30.565.10 72 224 2.1E-27 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_1c30760 e4abbb05dcf0fe8bba5ac72e972aaa4a 226 SUPERFAMILY SSF52172 1 176 1.24E-36 T 12-10-2018 IPR011006 CheY-like superfamily VAPA_1c30760 e4abbb05dcf0fe8bba5ac72e972aaa4a 226 SMART SM00862 149 222 1.6E-15 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 VAPA_1c30760 e4abbb05dcf0fe8bba5ac72e972aaa4a 226 Pfam PF00486 Transcriptional regulatory protein, C terminal 152 222 3.9E-17 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 VAPA_1c30760 e4abbb05dcf0fe8bba5ac72e972aaa4a 226 Gene3D G3DSA:3.40.50.2300 1 129 2.5E-33 T 12-10-2018 VAPA_1c30760 e4abbb05dcf0fe8bba5ac72e972aaa4a 226 SMART SM00448 1 112 1.2E-35 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_1c30760 e4abbb05dcf0fe8bba5ac72e972aaa4a 226 Pfam PF00072 Response regulator receiver domain 4 113 8.2E-25 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 VAPA_1c30760 e4abbb05dcf0fe8bba5ac72e972aaa4a 226 Gene3D G3DSA:1.10.10.10 130 226 5.3E-22 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c50800 8ce5c2b9c13f1dc02c805f04ffbb2974 151 SUPERFAMILY SSF53062 1 128 8.37E-27 T 12-10-2018 IPR036662 Phosphotransferase system, mannose-type IIA component superfamily GO:0009401|GO:0016021 VAPA_1c50800 8ce5c2b9c13f1dc02c805f04ffbb2974 151 Gene3D G3DSA:3.40.50.510 1 145 1.5E-29 T 12-10-2018 IPR036662 Phosphotransferase system, mannose-type IIA component superfamily GO:0009401|GO:0016021 VAPA_1c50800 8ce5c2b9c13f1dc02c805f04ffbb2974 151 Pfam PF03610 PTS system fructose IIA component 4 108 7.5E-14 T 12-10-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 VAPA_2c05920 9e1e24aaf86ce87333882b25bbc7267a 175 Pfam PF14340 Domain of unknown function (DUF4395) 12 135 5.4E-9 T 12-10-2018 IPR025508 Domain of unknown function DUF4395 VAPA_1c40140 ae690fc1c85f922ea75a736d0cd6f094 320 SUPERFAMILY SSF53850 107 281 1.55E-14 T 12-10-2018 VAPA_1c40140 ae690fc1c85f922ea75a736d0cd6f094 320 PIRSF PIRSF017082 1 320 2.6E-90 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c40140 ae690fc1c85f922ea75a736d0cd6f094 320 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 46 317 1.1E-92 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c40140 ae690fc1c85f922ea75a736d0cd6f094 320 Gene3D G3DSA:3.40.190.150 26 310 1.1E-113 T 12-10-2018 VAPA_1c40140 ae690fc1c85f922ea75a736d0cd6f094 320 Gene3D G3DSA:3.40.190.10 122 245 1.1E-113 T 12-10-2018 VAPA_1c54910 59cba3cf65b0efd62f5182e69e72e8b7 391 Gene3D G3DSA:1.20.1250.20 1 385 1.2E-31 T 12-10-2018 VAPA_1c54910 59cba3cf65b0efd62f5182e69e72e8b7 391 Pfam PF07690 Major Facilitator Superfamily 223 385 1.8E-10 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 VAPA_1c54910 59cba3cf65b0efd62f5182e69e72e8b7 391 SUPERFAMILY SSF103473 2 385 1.57E-33 T 12-10-2018 IPR036259 MFS transporter superfamily VAPA_1c27650 27e9f33b97fbd5663419ca4c80568e5c 166 Pfam PF14588 YjgF/chorismate_mutase-like, putative endoribonuclease 26 153 2.5E-24 T 12-10-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like VAPA_1c27650 27e9f33b97fbd5663419ca4c80568e5c 166 SUPERFAMILY SSF55298 15 156 1.12E-44 T 12-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 VAPA_1c27650 27e9f33b97fbd5663419ca4c80568e5c 166 Gene3D G3DSA:3.30.1330.40 5 157 2.8E-49 T 12-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 VAPA_1c01750 724dc2b04466b2e769ad3bd8aaf60637 244 SUPERFAMILY SSF46785 6 93 4.87E-16 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c01750 724dc2b04466b2e769ad3bd8aaf60637 244 Pfam PF07729 FCD domain 77 212 1.7E-20 T 12-10-2018 IPR011711 GntR, C-terminal VAPA_1c01750 724dc2b04466b2e769ad3bd8aaf60637 244 SMART SM00895 76 213 3.4E-20 T 12-10-2018 IPR011711 GntR, C-terminal VAPA_1c01750 724dc2b04466b2e769ad3bd8aaf60637 244 Pfam PF00392 Bacterial regulatory proteins, gntR family 6 63 2.2E-14 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_1c01750 724dc2b04466b2e769ad3bd8aaf60637 244 SUPERFAMILY SSF48008 72 216 2.62E-20 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal VAPA_1c01750 724dc2b04466b2e769ad3bd8aaf60637 244 SMART SM00345 8 66 3.9E-11 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 VAPA_1c01750 724dc2b04466b2e769ad3bd8aaf60637 244 Gene3D G3DSA:1.20.120.530 66 222 1.0E-27 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal VAPA_1c01750 724dc2b04466b2e769ad3bd8aaf60637 244 Gene3D G3DSA:1.10.10.10 3 65 1.4E-18 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c34750 00c59b9b1c6f87d652257e9313b99780 363 SUPERFAMILY SSF53955 47 359 3.37E-73 T 12-10-2018 IPR023346 Lysozyme-like domain superfamily VAPA_1c34750 00c59b9b1c6f87d652257e9313b99780 363 Gene3D G3DSA:1.10.530.10 94 357 4.0E-97 T 12-10-2018 VAPA_1c34750 00c59b9b1c6f87d652257e9313b99780 363 Gene3D G3DSA:1.10.8.350 53 227 4.0E-97 T 12-10-2018 VAPA_1c34750 00c59b9b1c6f87d652257e9313b99780 363 Pfam PF13406 Transglycosylase SLT domain 53 354 1.1E-85 T 12-10-2018 IPR031304 Transglycosylase SLT domain 2 VAPA_1c34750 00c59b9b1c6f87d652257e9313b99780 363 TIGRFAM TIGR02282 MltB: lytic murein transglycosylase B 55 357 1.8E-93 T 12-10-2018 IPR011757 Lytic transglycosylase MltB VAPA_1c13890 3c18121706354318c639b17424ce61e6 503 ProSitePatterns PS00455 Putative AMP-binding domain signature. 156 167 - T 12-10-2018 IPR020845 AMP-binding, conserved site VAPA_1c13890 3c18121706354318c639b17424ce61e6 503 Gene3D G3DSA:3.40.50.12780 1 399 1.7E-96 T 12-10-2018 VAPA_1c13890 3c18121706354318c639b17424ce61e6 503 SUPERFAMILY SSF56801 6 500 1.31E-133 T 12-10-2018 VAPA_1c13890 3c18121706354318c639b17424ce61e6 503 Gene3D G3DSA:3.30.300.30 400 501 4.6E-31 T 12-10-2018 VAPA_1c13890 3c18121706354318c639b17424ce61e6 503 Pfam PF13193 AMP-binding enzyme C-terminal domain 413 488 9.7E-15 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain VAPA_1c13890 3c18121706354318c639b17424ce61e6 503 Pfam PF00501 AMP-binding enzyme 12 404 3.6E-85 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 VAPA_1c31240 9b3f101eebae2050dd3a26feffd323a7 459 SUPERFAMILY SSF55874 319 451 2.1E-16 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_1c31240 9b3f101eebae2050dd3a26feffd323a7 459 Gene3D G3DSA:3.30.565.10 319 451 1.5E-25 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_1c31240 9b3f101eebae2050dd3a26feffd323a7 459 SMART SM00387 356 453 2.2E-5 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase VAPA_1c31240 9b3f101eebae2050dd3a26feffd323a7 459 SMART SM00304 167 219 1.1E-7 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 VAPA_1c31240 9b3f101eebae2050dd3a26feffd323a7 459 Pfam PF07730 Histidine kinase 248 313 6.0E-10 T 12-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 VAPA_1c09840 0e5542b7374ff3b1d03f9f66e0160b07 291 SUPERFAMILY SSF69593 10 92 3.14E-10 T 12-10-2018 VAPA_1c09840 0e5542b7374ff3b1d03f9f66e0160b07 291 SUPERFAMILY SSF69593 187 284 3.01E-16 T 12-10-2018 VAPA_1c09840 0e5542b7374ff3b1d03f9f66e0160b07 291 SMART SM00563 34 242 1.9E-7 T 12-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 VAPA_1c09840 0e5542b7374ff3b1d03f9f66e0160b07 291 Pfam PF01553 Acyltransferase 31 239 6.9E-15 T 12-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 VAPA_1c03300 7ad5db78ca415f1f783877070185ec38 353 Pfam PF02653 Branched-chain amino acid transport system / permease component 52 328 3.0E-37 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 VAPA_1c41770 b8634c7674f3fb3202170866260fc81b 133 SUPERFAMILY SSF54593 2 132 2.56E-37 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase VAPA_1c41770 b8634c7674f3fb3202170866260fc81b 133 Gene3D G3DSA:3.10.180.10 5 133 8.6E-53 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase VAPA_1c41770 b8634c7674f3fb3202170866260fc81b 133 Pfam PF06983 3-demethylubiquinone-9 3-methyltransferase 3 129 6.8E-13 T 12-10-2018 IPR028973 PhnB-like VAPA_1c35510 a56adb041f6a86959250a11684e2c96c 285 TIGRFAM TIGR01362 KDO8P_synth: 3-deoxy-8-phosphooctulonate synthase 13 275 2.4E-123 T 12-10-2018 IPR006269 3-deoxy-8-phosphooctulonate synthase GO:0005737|GO:0008676 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 VAPA_1c35510 a56adb041f6a86959250a11684e2c96c 285 SUPERFAMILY SSF51569 2 276 4.67E-103 T 12-10-2018 VAPA_1c35510 a56adb041f6a86959250a11684e2c96c 285 Pfam PF00793 DAHP synthetase I family 7 269 1.7E-67 T 12-10-2018 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 VAPA_1c35510 a56adb041f6a86959250a11684e2c96c 285 Gene3D G3DSA:3.20.20.70 3 281 4.9E-104 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 VAPA_1c35510 a56adb041f6a86959250a11684e2c96c 285 Hamap MF_00056 2-dehydro-3-deoxyphosphooctonate aldolase [kdsA]. 8 276 53.111 T 12-10-2018 IPR006269 3-deoxy-8-phosphooctulonate synthase GO:0005737|GO:0008676 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 VAPA_1c38160 7f29a5bf3a664b240c1a06e8f52e2f46 245 SUPERFAMILY SSF53639 9 222 1.1E-49 T 12-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily VAPA_1c38160 7f29a5bf3a664b240c1a06e8f52e2f46 245 SMART SM01007 17 198 4.3E-35 T 12-10-2018 IPR001303 Class II aldolase/adducin N-terminal VAPA_1c38160 7f29a5bf3a664b240c1a06e8f52e2f46 245 Gene3D G3DSA:3.40.225.10 5 242 1.0E-53 T 12-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily VAPA_1c38160 7f29a5bf3a664b240c1a06e8f52e2f46 245 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 18 194 2.2E-35 T 12-10-2018 IPR001303 Class II aldolase/adducin N-terminal VAPA_2c04900 a0523d8b4cb698689c463d341890d10b 146 Pfam PF01382 Avidin family 26 134 3.4E-18 T 12-10-2018 IPR005468 Avidin/streptavidin VAPA_2c04900 a0523d8b4cb698689c463d341890d10b 146 Gene3D G3DSA:2.40.128.30 13 138 8.7E-25 T 12-10-2018 IPR036896 Avidin-like superfamily VAPA_2c04900 a0523d8b4cb698689c463d341890d10b 146 SUPERFAMILY SSF50876 27 135 7.46E-20 T 12-10-2018 IPR036896 Avidin-like superfamily VAPA_1c02470 100f34c16cf4bafcb09eaa3289424c4a 458 SUPERFAMILY SSF103088 309 441 1.2E-26 T 12-10-2018 IPR036737 OmpA-like domain superfamily VAPA_1c02470 100f34c16cf4bafcb09eaa3289424c4a 458 Gene3D G3DSA:3.30.1330.60 293 444 1.2E-43 T 12-10-2018 IPR036737 OmpA-like domain superfamily VAPA_1c02470 100f34c16cf4bafcb09eaa3289424c4a 458 Pfam PF00691 OmpA family 337 435 1.2E-16 T 12-10-2018 IPR006665 OmpA-like domain VAPA_1c02470 100f34c16cf4bafcb09eaa3289424c4a 458 Pfam PF09850 Type VI secretion system protein DotU 70 271 1.9E-73 T 12-10-2018 IPR017732 Type IV / VI secretion system, DotU VAPA_1c02470 100f34c16cf4bafcb09eaa3289424c4a 458 Gene3D G3DSA:1.25.40.590 67 223 1.3E-56 T 12-10-2018 IPR038522 Type IV / VI secretion system, DotU superfamily VAPA_1c02470 100f34c16cf4bafcb09eaa3289424c4a 458 TIGRFAM TIGR03349 IV_VI_DotU: type IV/VI secretion system protein, DotU family 69 277 2.0E-75 T 12-10-2018 IPR017732 Type IV / VI secretion system, DotU VAPA_1c02470 100f34c16cf4bafcb09eaa3289424c4a 458 TIGRFAM TIGR03350 type_VI_ompA: type VI secretion system peptidoglycan-associated domain 305 440 1.5E-50 T 12-10-2018 IPR017733 Type VI secretion system peptidoglycan-associated domain VAPA_1c33590 c7f1ebdaab9cb3bbc6811ada61237d60 314 SUPERFAMILY SSF46785 3 86 1.09E-21 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c33590 c7f1ebdaab9cb3bbc6811ada61237d60 314 SUPERFAMILY SSF53850 93 295 7.82E-42 T 12-10-2018 VAPA_1c33590 c7f1ebdaab9cb3bbc6811ada61237d60 314 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 67 2.2E-18 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c33590 c7f1ebdaab9cb3bbc6811ada61237d60 314 Pfam PF03466 LysR substrate binding domain 92 290 1.2E-37 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_1c33590 c7f1ebdaab9cb3bbc6811ada61237d60 314 Gene3D G3DSA:3.40.190.10 163 261 1.7E-58 T 12-10-2018 VAPA_1c33590 c7f1ebdaab9cb3bbc6811ada61237d60 314 Gene3D G3DSA:1.10.10.10 7 95 7.7E-22 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c33590 c7f1ebdaab9cb3bbc6811ada61237d60 314 Gene3D G3DSA:3.40.190.10 103 288 1.7E-58 T 12-10-2018 VAPA_2c13180 e4415637581d69091a243db257f7cba9 368 Pfam PF03432 Relaxase/Mobilisation nuclease domain 129 228 5.9E-9 T 12-10-2018 IPR005094 Endonuclease relaxase, MobA/VirD2 VAPA_1c29310 60a579c043449e131581c3ab21b38bfe 252 SUPERFAMILY SSF53448 12 250 1.41E-27 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases VAPA_1c09630 69eecd0c83d16c6e5fcf807fa50b2d8e 142 Hamap MF_01008 Transcriptional regulator MraZ [mraZ]. 1 142 49.301 T 12-10-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 VAPA_1c09630 69eecd0c83d16c6e5fcf807fa50b2d8e 142 Gene3D G3DSA:2.40.330.20 1 139 1.7E-35 T 12-10-2018 IPR038619 MraZ superfamily VAPA_1c09630 69eecd0c83d16c6e5fcf807fa50b2d8e 142 Pfam PF02381 MraZ protein, putative antitoxin-like 73 128 8.5E-12 T 12-10-2018 IPR020603 MraZ domain VAPA_1c09630 69eecd0c83d16c6e5fcf807fa50b2d8e 142 Pfam PF02381 MraZ protein, putative antitoxin-like 2 67 6.4E-13 T 12-10-2018 IPR020603 MraZ domain VAPA_1c09630 69eecd0c83d16c6e5fcf807fa50b2d8e 142 TIGRFAM TIGR00242 TIGR00242: division/cell wall cluster transcriptional repressor MraZ 2 138 3.5E-32 T 12-10-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 VAPA_1c09630 69eecd0c83d16c6e5fcf807fa50b2d8e 142 ProDom PD006745 MRAZ YABB DIVISION CELL 3D-STRUCTURE UNCHARACTERIZED BCR SIMILAR PROTEIN 2 117 4.0E-59 T 12-10-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 VAPA_1c09630 69eecd0c83d16c6e5fcf807fa50b2d8e 142 SUPERFAMILY SSF89447 2 129 1.12E-38 T 12-10-2018 IPR037914 SpoVT-AbrB domain superfamily VAPA_1c08380 98676f0dbc26aff3c4533d7e0939da21 345 Pfam PF16363 GDP-mannose 4,6 dehydratase 7 326 4.7E-58 T 12-10-2018 IPR016040 NAD(P)-binding domain VAPA_1c08380 98676f0dbc26aff3c4533d7e0939da21 345 Gene3D G3DSA:3.40.50.720 6 276 3.6E-137 T 12-10-2018 VAPA_1c08380 98676f0dbc26aff3c4533d7e0939da21 345 TIGRFAM TIGR01179 galE: UDP-glucose 4-epimerase GalE 6 337 5.7E-134 T 12-10-2018 IPR005886 UDP-glucose 4-epimerase GO:0003978|GO:0006012 KEGG: 00052+5.1.3.2|KEGG: 00520+5.1.3.2|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6397|MetaCyc: PWY-6527|MetaCyc: PWY-7328|MetaCyc: PWY-7344|Reactome: R-HSA-5609977|Reactome: R-HSA-70370 VAPA_1c08380 98676f0dbc26aff3c4533d7e0939da21 345 Gene3D G3DSA:3.90.25.10 196 331 3.6E-137 T 12-10-2018 VAPA_1c08380 98676f0dbc26aff3c4533d7e0939da21 345 SUPERFAMILY SSF51735 1 339 9.86E-97 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_2c01600 8eef706b888fcda706c628ce2a839662 133 Gene3D G3DSA:3.10.180.10 1 128 3.8E-31 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase VAPA_2c01600 8eef706b888fcda706c628ce2a839662 133 SUPERFAMILY SSF54593 2 127 2.2E-19 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase VAPA_2c01600 8eef706b888fcda706c628ce2a839662 133 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 2 124 1.7E-6 T 12-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain VAPA_2c03550 68a5d3c9b76f609bdad21d40b5a12028 174 SUPERFAMILY SSF54631 1 132 8.09E-28 T 12-10-2018 VAPA_2c03550 68a5d3c9b76f609bdad21d40b5a12028 174 Pfam PF00571 CBS domain 72 126 1.4E-10 T 12-10-2018 IPR000644 CBS domain VAPA_2c03550 68a5d3c9b76f609bdad21d40b5a12028 174 Pfam PF00571 CBS domain 4 57 6.8E-8 T 12-10-2018 IPR000644 CBS domain VAPA_2c03550 68a5d3c9b76f609bdad21d40b5a12028 174 Gene3D G3DSA:3.10.580.10 1 151 8.1E-32 T 12-10-2018 VAPA_2c03550 68a5d3c9b76f609bdad21d40b5a12028 174 SMART SM00116 79 127 5.5E-8 T 12-10-2018 IPR000644 CBS domain VAPA_2c03550 68a5d3c9b76f609bdad21d40b5a12028 174 SMART SM00116 10 61 0.0011 T 12-10-2018 IPR000644 CBS domain VAPA_1c41080 284426b238660287df16ecce8d4eeae0 137 SUPERFAMILY SSF54593 3 133 1.51E-17 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase VAPA_1c41080 284426b238660287df16ecce8d4eeae0 137 Gene3D G3DSA:3.10.180.10 2 133 2.0E-45 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase VAPA_1c30740 e394693488903d263c2b9d4a64bda5d0 178 Pfam PF07331 Tripartite tricarboxylate transporter TctB family 21 170 4.9E-19 T 12-10-2018 IPR009936 Protein of unknown function DUF1468 VAPA_2c06340 841f4b3585a211b2d1fab15d09b07347 262 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 82 101 2.8E-30 T 12-10-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 VAPA_2c06340 841f4b3585a211b2d1fab15d09b07347 262 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 25 46 2.8E-30 T 12-10-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 VAPA_2c06340 841f4b3585a211b2d1fab15d09b07347 262 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 184 206 2.8E-30 T 12-10-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 VAPA_2c06340 841f4b3585a211b2d1fab15d09b07347 262 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 206 225 2.8E-30 T 12-10-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 VAPA_2c06340 841f4b3585a211b2d1fab15d09b07347 262 TIGRFAM TIGR01401 fliR_like_III: type III secretion apparatus protein SpaR/YscT/HrcT 12 256 8.1E-59 T 12-10-2018 IPR006304 Type III secretion protein SpaR/YscT GO:0016021 VAPA_2c06340 841f4b3585a211b2d1fab15d09b07347 262 Pfam PF01311 Bacterial export proteins, family 1 18 247 2.0E-54 T 12-10-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 VAPA_1c16390 42c40236c6e2f5dc151d8ae49248aa4f 300 Pfam PF03466 LysR substrate binding domain 88 295 1.5E-30 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_1c16390 42c40236c6e2f5dc151d8ae49248aa4f 300 Gene3D G3DSA:1.10.10.10 1 92 6.3E-20 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c16390 42c40236c6e2f5dc151d8ae49248aa4f 300 SUPERFAMILY SSF53850 91 298 2.79E-33 T 12-10-2018 VAPA_1c16390 42c40236c6e2f5dc151d8ae49248aa4f 300 Gene3D G3DSA:3.40.190.290 93 299 2.2E-30 T 12-10-2018 VAPA_1c16390 42c40236c6e2f5dc151d8ae49248aa4f 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.2E-5 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c16390 42c40236c6e2f5dc151d8ae49248aa4f 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.2E-5 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c16390 42c40236c6e2f5dc151d8ae49248aa4f 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.2E-5 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c16390 42c40236c6e2f5dc151d8ae49248aa4f 300 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 6.6E-18 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c16390 42c40236c6e2f5dc151d8ae49248aa4f 300 SUPERFAMILY SSF46785 1 111 1.03E-18 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c55000 4bbd9b5f673bafa40b82dfff243334d5 187 Pfam PF01169 Uncharacterized protein family UPF0016 105 180 1.3E-22 T 12-10-2018 IPR001727 Gdt1 family VAPA_1c55000 4bbd9b5f673bafa40b82dfff243334d5 187 Pfam PF01169 Uncharacterized protein family UPF0016 6 80 3.9E-21 T 12-10-2018 IPR001727 Gdt1 family VAPA_2c12870 c78dae5d0648f3ca013744c500e1b15c 367 Gene3D G3DSA:1.10.287.110 202 251 7.8E-6 T 12-10-2018 IPR036869 Chaperone J-domain superfamily VAPA_2c12870 c78dae5d0648f3ca013744c500e1b15c 367 SUPERFAMILY SSF46565 204 243 7.59E-7 T 12-10-2018 IPR036869 Chaperone J-domain superfamily VAPA_1c04870 40f054e3949c6d658662e6c8f9fc70dd 235 Pfam PF01618 MotA/TolQ/ExbB proton channel family 94 206 7.0E-32 T 12-10-2018 IPR002898 MotA/TolQ/ExbB proton channel VAPA_1c53780 57a049bacc1c3981fb22e6ff66354801 198 Pfam PF02397 Bacterial sugar transferase 3 196 3.4E-56 T 12-10-2018 IPR003362 Bacterial sugar transferase VAPA_1c20760 6fd7f8b64c7862915892d57223eb31a0 264 Hamap MF_00905 3',5'-cyclic adenosine monophosphate phosphodiesterase CpdA [cpdA]. 1 254 39.617 T 12-10-2018 IPR026575 3,5-cyclic adenosine monophosphate phosphodiesterase CpdA GO:0004115 KEGG: 00230+3.1.4.53 VAPA_1c20760 6fd7f8b64c7862915892d57223eb31a0 264 Gene3D G3DSA:3.60.21.40 1 239 1.8E-85 T 12-10-2018 VAPA_1c20760 6fd7f8b64c7862915892d57223eb31a0 264 SUPERFAMILY SSF56300 1 248 6.08E-55 T 12-10-2018 VAPA_1c20760 6fd7f8b64c7862915892d57223eb31a0 264 Pfam PF00149 Calcineurin-like phosphoesterase 2 196 2.0E-18 T 12-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 VAPA_1c20760 6fd7f8b64c7862915892d57223eb31a0 264 Gene3D G3DSA:3.30.750.180 104 230 1.8E-85 T 12-10-2018 VAPA_1c53830 2fba91644b3fe65705530c75cef51160 229 Gene3D G3DSA:3.40.50.150 27 190 3.2E-22 T 12-10-2018 VAPA_1c53830 2fba91644b3fe65705530c75cef51160 229 SUPERFAMILY SSF53335 6 187 7.12E-26 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase VAPA_1c53830 2fba91644b3fe65705530c75cef51160 229 Pfam PF08241 Methyltransferase domain 59 154 8.1E-16 T 12-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 VAPA_1c32030 585a6d539901500c08551f089d67aca8 196 Gene3D G3DSA:1.10.3210.10 36 188 5.7E-17 T 12-10-2018 VAPA_1c32030 585a6d539901500c08551f089d67aca8 196 SUPERFAMILY SSF109604 7 131 3.73E-29 T 12-10-2018 VAPA_1c32030 585a6d539901500c08551f089d67aca8 196 Pfam PF01966 HD domain 54 122 1.4E-4 T 12-10-2018 IPR006674 HD domain VAPA_1c20930 a1ef23f323b80cb541dcb4ec96d6b677 148 Gene3D G3DSA:3.10.180.10 1 120 2.8E-47 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase VAPA_1c20930 a1ef23f323b80cb541dcb4ec96d6b677 148 SUPERFAMILY SSF54593 2 120 7.65E-18 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase VAPA_1c40860 5200065a5c8f15fad11b8e9755a45913 445 SUPERFAMILY SSF53448 80 366 1.53E-56 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases VAPA_1c40860 5200065a5c8f15fad11b8e9755a45913 445 Pfam PF00535 Glycosyl transferase family 2 95 265 1.1E-27 T 12-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 VAPA_1c40860 5200065a5c8f15fad11b8e9755a45913 445 Gene3D G3DSA:3.90.550.10 87 312 7.0E-41 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases VAPA_1c16140 6fe232b485dbe7665587c74e7435e649 280 Pfam PF16976 Flp pilus assembly protein RcpC/CpaB 105 213 1.5E-29 T 12-10-2018 IPR031571 Flp pilus assembly protein RcpC/CpaB domain VAPA_1c16140 6fe232b485dbe7665587c74e7435e649 280 TIGRFAM TIGR03177 pilus_cpaB: Flp pilus assembly protein CpaB 9 273 2.9E-72 T 12-10-2018 IPR017592 Pilus assembly, Flp-type CpaB VAPA_1c16140 6fe232b485dbe7665587c74e7435e649 280 Pfam PF08666 SAF domain 39 97 1.2E-5 T 12-10-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 VAPA_1c16140 6fe232b485dbe7665587c74e7435e649 280 SMART SM00858 37 99 1.5E-8 T 12-10-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 VAPA_1c12700 ee90e0df286095fd6068e0694ae9f91e 418 TIGRFAM TIGR02212 lolCE: lipoprotein releasing system, transmembrane protein, LolC/E family 5 418 1.9E-142 T 12-10-2018 IPR011925 Lipoprotein-releasing system transmembrane protein LolC/E GO:0016021|GO:0042953|GO:0042954 VAPA_1c12700 ee90e0df286095fd6068e0694ae9f91e 418 Pfam PF12704 MacB-like periplasmic core domain 30 245 2.0E-20 T 12-10-2018 IPR025857 MacB-like periplasmic core domain VAPA_1c12700 ee90e0df286095fd6068e0694ae9f91e 418 Pfam PF02687 FtsX-like permease family 305 411 1.5E-14 T 12-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 VAPA_2c09290 4061e373b5b2f9eab0dd778ffc0ce77b 338 Pfam PF02371 Transposase IS116/IS110/IS902 family 213 298 7.0E-15 T 12-10-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 VAPA_2c09290 4061e373b5b2f9eab0dd778ffc0ce77b 338 Pfam PF01548 Transposase 6 147 6.6E-17 T 12-10-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 VAPA_1c06490 2f48bac25e44864efd9e2ac76360b063 441 Pfam PF06527 TniQ 7 160 8.3E-11 T 12-10-2018 IPR009492 TniQ VAPA_1c18980 60a64949f048f50241b96d8070c49485 190 Pfam PF10417 C-terminal domain of 1-Cys peroxiredoxin 159 185 2.4E-6 T 12-10-2018 IPR019479 Peroxiredoxin, C-terminal GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 VAPA_1c18980 60a64949f048f50241b96d8070c49485 190 TIGRFAM TIGR03137 AhpC: peroxiredoxin 1 190 9.1E-102 T 12-10-2018 IPR017559 Alkyl hydroperoxide reductase subunit C GO:0006979|GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 VAPA_1c18980 60a64949f048f50241b96d8070c49485 190 Pfam PF00578 AhpC/TSA family 7 135 1.9E-36 T 12-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 VAPA_1c18980 60a64949f048f50241b96d8070c49485 190 Gene3D G3DSA:3.40.30.10 1 189 3.3E-66 T 12-10-2018 VAPA_1c18980 60a64949f048f50241b96d8070c49485 190 PIRSF PIRSF000239 1 190 2.8E-59 T 12-10-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 VAPA_1c18980 60a64949f048f50241b96d8070c49485 190 SUPERFAMILY SSF52833 1 189 6.73E-61 T 12-10-2018 IPR036249 Thioredoxin-like superfamily VAPA_1c39970 522106f5ee66fcbc737b3a454817160c 188 Hamap MF_00146 dCTP deaminase [dcd]. 1 188 28.01 T 12-10-2018 IPR011962 dCTP deaminase GO:0006229|GO:0008829 VAPA_1c39970 522106f5ee66fcbc737b3a454817160c 188 SUPERFAMILY SSF51283 3 187 1.83E-53 T 12-10-2018 IPR036157 dUTPase-like superfamily VAPA_1c39970 522106f5ee66fcbc737b3a454817160c 188 Gene3D G3DSA:2.70.40.10 1 160 4.5E-54 T 12-10-2018 IPR036157 dUTPase-like superfamily VAPA_1c39970 522106f5ee66fcbc737b3a454817160c 188 Pfam PF00692 dUTPase 80 184 2.0E-6 T 12-10-2018 IPR029054 dUTPase-like VAPA_1c39970 522106f5ee66fcbc737b3a454817160c 188 TIGRFAM TIGR02274 dCTP_deam: deoxycytidine triphosphate deaminase 4 187 3.7E-49 T 12-10-2018 IPR011962 dCTP deaminase GO:0006229|GO:0008829 VAPA_1c17490 33ef85a89292bfdec2f9299d0e4e44fa 337 Pfam PF03706 Lysylphosphatidylglycerol synthase TM region 31 306 9.8E-18 T 12-10-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD VAPA_1c43300 16b80cd43f55df784ef8e477735798de 454 Pfam PF02120 Flagellar hook-length control protein FliK 316 396 4.5E-18 T 12-10-2018 IPR021136 Flagellar hook-length control protein-like, C-terminal VAPA_1c43300 16b80cd43f55df784ef8e477735798de 454 Gene3D G3DSA:3.30.750.140 297 416 2.9E-31 T 12-10-2018 IPR038610 FliK-like, C-terminal domain superfamily VAPA_1c18340 8ad8493e5c087d0eb80a69379ea029e9 391 Gene3D G3DSA:3.40.50.2300 31 359 4.8E-113 T 12-10-2018 VAPA_1c18340 8ad8493e5c087d0eb80a69379ea029e9 391 SUPERFAMILY SSF53822 30 382 1.82E-81 T 12-10-2018 IPR028082 Periplasmic binding protein-like I VAPA_1c18340 8ad8493e5c087d0eb80a69379ea029e9 391 Pfam PF13458 Periplasmic binding protein 31 371 4.5E-65 T 12-10-2018 IPR028081 Leucine-binding protein domain VAPA_1c18340 8ad8493e5c087d0eb80a69379ea029e9 391 Gene3D G3DSA:3.40.50.2300 145 371 4.8E-113 T 12-10-2018 VAPA_1c03210 1590bbe75595fee0720173c862ea7549 287 Pfam PF01435 Peptidase family M48 113 272 1.6E-33 T 12-10-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 VAPA_2c00420 e884ec98d25456c5dff28f404edd2408 323 Gene3D G3DSA:3.40.190.150 27 312 5.9E-108 T 12-10-2018 VAPA_2c00420 e884ec98d25456c5dff28f404edd2408 323 Gene3D G3DSA:3.40.190.10 124 247 5.9E-108 T 12-10-2018 VAPA_2c00420 e884ec98d25456c5dff28f404edd2408 323 PIRSF PIRSF017082 2 320 2.3E-78 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_2c00420 e884ec98d25456c5dff28f404edd2408 323 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 46 318 1.6E-79 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_2c00420 e884ec98d25456c5dff28f404edd2408 323 SUPERFAMILY SSF53850 112 282 2.82E-12 T 12-10-2018 VAPA_1c31370 e19e9d707cf33a48571b6d7c9242caef 234 PIRSF PIRSF015957 3 233 6.4E-41 T 12-10-2018 IPR007565 (5-formylfuran-3-yl)methyl phosphate synthase KEGG: 00680+4.2.3.153|MetaCyc: PWY-5254 VAPA_1c31370 e19e9d707cf33a48571b6d7c9242caef 234 Pfam PF04476 4-HFC-P synthase 5 220 5.5E-56 T 12-10-2018 IPR007565 (5-formylfuran-3-yl)methyl phosphate synthase KEGG: 00680+4.2.3.153|MetaCyc: PWY-5254 VAPA_2c10300 caae7b2e552043c18db8421e28938e84 402 Gene3D G3DSA:3.30.450.20 176 288 1.4E-5 T 12-10-2018 VAPA_2c10300 caae7b2e552043c18db8421e28938e84 402 Pfam PF08448 PAS fold 187 285 5.0E-5 T 12-10-2018 IPR013656 PAS fold-4 VAPA_2c10300 caae7b2e552043c18db8421e28938e84 402 SMART SM00421 313 370 2.1E-4 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_2c10300 caae7b2e552043c18db8421e28938e84 402 Gene3D G3DSA:1.10.10.10 308 372 7.0E-9 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_2c10300 caae7b2e552043c18db8421e28938e84 402 SUPERFAMILY SSF46894 297 371 2.86E-11 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 VAPA_1c37020 a88f040c96ed96b1eb6f34c6c16f4646 296 Gene3D G3DSA:2.60.120.620 81 284 8.6E-52 T 12-10-2018 VAPA_1c37020 a88f040c96ed96b1eb6f34c6c16f4646 296 SMART SM00702 99 283 4.8E-36 T 12-10-2018 IPR006620 Prolyl 4-hydroxylase, alpha subunit GO:0005506|GO:0016705|GO:0031418|GO:0055114 VAPA_1c37020 a88f040c96ed96b1eb6f34c6c16f4646 296 Pfam PF13640 2OG-Fe(II) oxygenase superfamily 179 283 1.2E-13 T 12-10-2018 IPR005123 Oxoglutarate/iron-dependent dioxygenase GO:0016491|GO:0055114 VAPA_1c13550 2b9a014fb7df75b48d88ec99bd3c76ef 309 Pfam PF02653 Branched-chain amino acid transport system / permease component 8 293 3.7E-48 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 VAPA_1c28780 e75abe92877f819b70b61fcb58e1779e 503 Pfam PF05872 Bacterial protein of unknown function (DUF853) 5 503 3.4E-230 T 12-10-2018 IPR033186 Helicase HerA-like C-terminal VAPA_1c28780 e75abe92877f819b70b61fcb58e1779e 503 Gene3D G3DSA:3.40.50.300 201 374 1.1E-19 T 12-10-2018 VAPA_1c28780 e75abe92877f819b70b61fcb58e1779e 503 Gene3D G3DSA:3.40.50.300 9 82 1.4E-9 T 12-10-2018 VAPA_1c28780 e75abe92877f819b70b61fcb58e1779e 503 SUPERFAMILY SSF52540 19 368 4.33E-53 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c22250 2f70619bf875ac4ba00bad299b13dc83 146 Pfam PF13474 SnoaL-like domain 19 135 1.5E-12 T 12-10-2018 IPR037401 SnoaL-like domain VAPA_1c22250 2f70619bf875ac4ba00bad299b13dc83 146 SUPERFAMILY SSF54427 5 134 3.0E-25 T 12-10-2018 IPR032710 NTF2-like domain superfamily VAPA_1c22250 2f70619bf875ac4ba00bad299b13dc83 146 Gene3D G3DSA:3.10.450.50 2 137 2.2E-31 T 12-10-2018 VAPA_1c53240 ed34c8cb859d58c07a0417df7ff4e103 267 Pfam PF00005 ABC transporter 29 171 3.5E-28 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c53240 ed34c8cb859d58c07a0417df7ff4e103 267 Gene3D G3DSA:3.40.50.300 6 240 8.0E-56 T 12-10-2018 VAPA_1c53240 ed34c8cb859d58c07a0417df7ff4e103 267 ProSitePatterns PS00211 ABC transporters family signature. 143 157 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_1c53240 ed34c8cb859d58c07a0417df7ff4e103 267 SMART SM00382 38 230 7.8E-12 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c53240 ed34c8cb859d58c07a0417df7ff4e103 267 SUPERFAMILY SSF52540 12 238 2.58E-63 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c19750 fbb5ef21542f904fe315298728ba4543 218 Gene3D G3DSA:1.10.287.110 158 217 1.1E-9 T 12-10-2018 IPR036869 Chaperone J-domain superfamily VAPA_1c19750 fbb5ef21542f904fe315298728ba4543 218 SUPERFAMILY SSF46565 162 211 6.8E-11 T 12-10-2018 IPR036869 Chaperone J-domain superfamily VAPA_2c04880 2aefe895449eb978aa2d817f5fbedcbc 128 Pfam PF00571 CBS domain 6 59 1.7E-9 T 12-10-2018 IPR000644 CBS domain VAPA_2c04880 2aefe895449eb978aa2d817f5fbedcbc 128 Pfam PF00571 CBS domain 74 122 2.4E-7 T 12-10-2018 IPR000644 CBS domain VAPA_2c04880 2aefe895449eb978aa2d817f5fbedcbc 128 SUPERFAMILY SSF54631 4 124 5.68E-25 T 12-10-2018 VAPA_2c04880 2aefe895449eb978aa2d817f5fbedcbc 128 Gene3D G3DSA:3.10.580.10 2 128 1.2E-24 T 12-10-2018 VAPA_2c04880 2aefe895449eb978aa2d817f5fbedcbc 128 SMART SM00116 78 125 0.0016 T 12-10-2018 IPR000644 CBS domain VAPA_2c04880 2aefe895449eb978aa2d817f5fbedcbc 128 SMART SM00116 12 61 0.087 T 12-10-2018 IPR000644 CBS domain VAPA_1c22780 8084e1023c674b3038f1ba1cad5b75e1 323 Gene3D G3DSA:3.40.190.150 27 313 1.6E-85 T 12-10-2018 VAPA_1c22780 8084e1023c674b3038f1ba1cad5b75e1 323 SUPERFAMILY SSF53850 109 289 2.9E-9 T 12-10-2018 VAPA_1c22780 8084e1023c674b3038f1ba1cad5b75e1 323 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 47 319 1.8E-63 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c22780 8084e1023c674b3038f1ba1cad5b75e1 323 Gene3D G3DSA:3.40.190.10 124 248 1.6E-85 T 12-10-2018 VAPA_1c22780 8084e1023c674b3038f1ba1cad5b75e1 323 PIRSF PIRSF017082 4 322 1.2E-56 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c49570 0b9d7e8628cba1dfdaae10d3550fe284 422 SUPERFAMILY SSF52266 204 416 8.55E-45 T 12-10-2018 VAPA_1c49570 0b9d7e8628cba1dfdaae10d3550fe284 422 ProSitePatterns PS01098 Lipolytic enzymes "G-D-S-L" family, serine active site. 212 223 - T 12-10-2018 IPR008265 Lipase, GDSL, active site GO:0006629|GO:0016298 Reactome: R-HSA-1482788|Reactome: R-HSA-975634 VAPA_1c49570 0b9d7e8628cba1dfdaae10d3550fe284 422 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 214 410 2.6E-25 T 12-10-2018 IPR013830 SGNH hydrolase-type esterase domain VAPA_1c49570 0b9d7e8628cba1dfdaae10d3550fe284 422 Gene3D G3DSA:3.40.50.1110 202 421 9.9E-35 T 12-10-2018 IPR036514 SGNH hydrolase superfamily VAPA_1c01560 2b64915a191bca4bb8c713500a01e120 397 Gene3D G3DSA:3.40.50.2300 153 386 9.5E-145 T 12-10-2018 VAPA_1c01560 2b64915a191bca4bb8c713500a01e120 397 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 60 76 1.5E-6 T 12-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 VAPA_1c01560 2b64915a191bca4bb8c713500a01e120 397 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 38 54 1.5E-6 T 12-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 VAPA_1c01560 2b64915a191bca4bb8c713500a01e120 397 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 289 302 1.5E-6 T 12-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 VAPA_1c01560 2b64915a191bca4bb8c713500a01e120 397 Gene3D G3DSA:3.40.50.2300 41 366 9.5E-145 T 12-10-2018 VAPA_1c01560 2b64915a191bca4bb8c713500a01e120 397 SUPERFAMILY SSF53822 37 394 4.71E-103 T 12-10-2018 IPR028082 Periplasmic binding protein-like I VAPA_1c01560 2b64915a191bca4bb8c713500a01e120 397 TIGRFAM TIGR03407 urea_ABC_UrtA: urea ABC transporter, urea binding protein 38 394 5.2E-159 T 12-10-2018 IPR017777 Urea ABC transporter, substrate-binding protein UrtA-like VAPA_1c01560 2b64915a191bca4bb8c713500a01e120 397 Pfam PF13433 Periplasmic binding protein domain 38 396 4.8E-142 T 12-10-2018 VAPA_2c04120 0faa71d89c66c652b1c57ed156de2007 249 Gene3D G3DSA:3.30.559.10 4 244 2.7E-82 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 VAPA_2c04120 0faa71d89c66c652b1c57ed156de2007 249 SUPERFAMILY SSF52777 8 241 1.33E-73 T 12-10-2018 VAPA_2c04120 0faa71d89c66c652b1c57ed156de2007 249 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 18 242 1.6E-73 T 12-10-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0016746 Reactome: R-HSA-389661 VAPA_1c11950 8da15e621f7175897d3599d5e332100b 222 Hamap MF_01207 Protein-methionine-sulfoxide reductase heme-binding subunit MsrQ [msrQ]. 6 202 20.662 T 12-10-2018 IPR022837 Protein-methionine-sulfoxide reductase subunit MsrQ GO:0005887|GO:0030091 VAPA_1c11950 8da15e621f7175897d3599d5e332100b 222 Pfam PF01794 Ferric reductase like transmembrane component 62 159 4.5E-14 T 12-10-2018 IPR013130 Ferric reductase transmembrane component-like domain VAPA_2c09960 99207cc0ed775ba983cdbe0e14ffbb15 263 SUPERFAMILY SSF51735 6 258 7.73E-67 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_2c09960 99207cc0ed775ba983cdbe0e14ffbb15 263 Gene3D G3DSA:3.40.50.720 2 263 7.2E-72 T 12-10-2018 VAPA_2c09960 99207cc0ed775ba983cdbe0e14ffbb15 263 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 258 2.2E-44 T 12-10-2018 VAPA_2c09960 99207cc0ed775ba983cdbe0e14ffbb15 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 3.2E-27 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c09960 99207cc0ed775ba983cdbe0e14ffbb15 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 3.2E-27 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c09960 99207cc0ed775ba983cdbe0e14ffbb15 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 3.2E-27 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c09960 99207cc0ed775ba983cdbe0e14ffbb15 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 3.2E-27 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c09960 99207cc0ed775ba983cdbe0e14ffbb15 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 3.2E-27 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c09960 99207cc0ed775ba983cdbe0e14ffbb15 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 222 242 3.2E-27 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c09960 99207cc0ed775ba983cdbe0e14ffbb15 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 80 91 9.5E-5 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c09960 99207cc0ed775ba983cdbe0e14ffbb15 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 141 9.5E-5 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c09960 99207cc0ed775ba983cdbe0e14ffbb15 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 9.5E-5 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c12940 080dae13eea95a3ae5f51f6f98372709 250 SMART SM00382 36 223 5.3E-16 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_2c12940 080dae13eea95a3ae5f51f6f98372709 250 SUPERFAMILY SSF52540 11 244 2.23E-73 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_2c12940 080dae13eea95a3ae5f51f6f98372709 250 Pfam PF00005 ABC transporter 27 175 8.6E-36 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_2c12940 080dae13eea95a3ae5f51f6f98372709 250 Gene3D G3DSA:3.40.50.300 8 250 2.2E-73 T 12-10-2018 VAPA_2c12940 080dae13eea95a3ae5f51f6f98372709 250 ProSitePatterns PS00211 ABC transporters family signature. 147 161 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_2c12940 080dae13eea95a3ae5f51f6f98372709 250 PIRSF PIRSF039085 8 250 3.2E-98 T 12-10-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 VAPA_2c05890 da56aa70ed8bb54bc31530e287d11d2d 143 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 15 132 3.6E-5 T 12-10-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family VAPA_1c18350 7d79005357e24a4ad0dd4581ae9dee2d 290 Pfam PF02653 Branched-chain amino acid transport system / permease component 5 276 1.4E-38 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 VAPA_1c32550 9b691074b41112bfdb1caa61abe9957e 280 Gene3D G3DSA:3.40.50.720 1 279 6.7E-69 T 12-10-2018 VAPA_1c32550 9b691074b41112bfdb1caa61abe9957e 280 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 97 108 1.8E-28 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c32550 9b691074b41112bfdb1caa61abe9957e 280 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 195 212 1.8E-28 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c32550 9b691074b41112bfdb1caa61abe9957e 280 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 21 38 1.8E-28 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c32550 9b691074b41112bfdb1caa61abe9957e 280 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 240 260 1.8E-28 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c32550 9b691074b41112bfdb1caa61abe9957e 280 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 193 1.8E-28 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c32550 9b691074b41112bfdb1caa61abe9957e 280 SUPERFAMILY SSF51735 19 277 2.2E-65 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c32550 9b691074b41112bfdb1caa61abe9957e 280 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 28 277 5.7E-43 T 12-10-2018 VAPA_1c30580 f0a2bfd7d6654ad466c53f0247667ea2 168 SUPERFAMILY SSF109854 4 167 4.53E-58 T 12-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes VAPA_1c30580 f0a2bfd7d6654ad466c53f0247667ea2 168 Gene3D G3DSA:1.20.120.450 1 168 1.6E-57 T 12-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes VAPA_1c30580 f0a2bfd7d6654ad466c53f0247667ea2 168 Pfam PF09351 Domain of unknown function (DUF1993) 5 165 6.8E-60 T 12-10-2018 IPR018531 Protein of unknown function DUF1993 VAPA_1c23050 b99f3f3bb8f229077854bcd956087d52 308 SUPERFAMILY SSF103481 211 301 7.85E-15 T 12-10-2018 VAPA_1c23050 b99f3f3bb8f229077854bcd956087d52 308 Pfam PF00892 EamA-like transporter family 164 298 1.3E-17 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 VAPA_1c23050 b99f3f3bb8f229077854bcd956087d52 308 Pfam PF00892 EamA-like transporter family 24 153 5.4E-12 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 VAPA_1c23050 b99f3f3bb8f229077854bcd956087d52 308 SUPERFAMILY SSF103481 57 157 5.89E-10 T 12-10-2018 VAPA_1c28650 037eaa6e05647986f89311011319120f 343 Gene3D G3DSA:3.30.1330.40 202 338 7.4E-22 T 12-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 VAPA_1c28650 037eaa6e05647986f89311011319120f 343 Pfam PF01042 Endoribonuclease L-PSP 231 336 2.8E-7 T 12-10-2018 IPR006175 YjgF/YER057c/UK114 family Reactome: R-HSA-8849175 VAPA_1c28650 037eaa6e05647986f89311011319120f 343 SUPERFAMILY SSF55298 203 337 6.13E-14 T 12-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 VAPA_1c30340 6b1f1ee188bc79e9e52ef95d775297c1 335 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 41 315 8.6E-49 T 12-10-2018 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0022857|GO:0043190|GO:0055085 VAPA_1c30340 6b1f1ee188bc79e9e52ef95d775297c1 335 Gene3D G3DSA:3.40.190.100 119 258 3.1E-136 T 12-10-2018 VAPA_1c30340 6b1f1ee188bc79e9e52ef95d775297c1 335 SUPERFAMILY SSF53850 30 333 7.33E-82 T 12-10-2018 VAPA_1c30340 6b1f1ee188bc79e9e52ef95d775297c1 335 Gene3D G3DSA:3.40.190.10 31 330 3.1E-136 T 12-10-2018 VAPA_1c52490 9bd2522efa9d3e830e23801d6aec49d6 101 Pfam PF00253 Ribosomal protein S14p/S29e 48 100 4.0E-25 T 12-10-2018 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 VAPA_1c52490 9bd2522efa9d3e830e23801d6aec49d6 101 Hamap MF_00537 30S ribosomal protein S14 [rpsN]. 1 101 26.597 T 12-10-2018 IPR023036 Ribosomal protein S14, bacterial/plastid VAPA_1c52490 9bd2522efa9d3e830e23801d6aec49d6 101 SUPERFAMILY SSF57716 2 101 5.2E-36 T 12-10-2018 VAPA_1c52490 9bd2522efa9d3e830e23801d6aec49d6 101 Gene3D G3DSA:4.10.830.10 40 101 6.2E-23 T 12-10-2018 VAPA_1c51240 36a62950df9c190bef4d317a8019edd0 314 Gene3D G3DSA:3.40.50.1820 1 312 1.2E-99 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c51240 36a62950df9c190bef4d317a8019edd0 314 Pfam PF07859 alpha/beta hydrolase fold 81 287 4.1E-75 T 12-10-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0016787 VAPA_1c51240 36a62950df9c190bef4d317a8019edd0 314 SUPERFAMILY SSF53474 16 311 1.59E-76 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c51240 36a62950df9c190bef4d317a8019edd0 314 ProSitePatterns PS01173 Lipolytic enzymes "G-D-X-G" family, putative histidine active site. 81 97 - T 12-10-2018 IPR002168 Lipase, GDXG, putative histidine active site GO:0016787 Reactome: R-HSA-163560 VAPA_2c02490 ae4721c7022c46e895f33c84df560db6 146 ProSitePatterns PS00893 Nudix box signature. 33 54 - T 12-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 VAPA_2c02490 ae4721c7022c46e895f33c84df560db6 146 Pfam PF00293 NUDIX domain 2 133 6.9E-19 T 12-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 VAPA_2c02490 ae4721c7022c46e895f33c84df560db6 146 SUPERFAMILY SSF55811 5 129 2.71E-25 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 VAPA_2c02490 ae4721c7022c46e895f33c84df560db6 146 PRINTS PR00502 NUDIX hydrolase family signature 42 57 6.4E-7 T 12-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 VAPA_2c02490 ae4721c7022c46e895f33c84df560db6 146 PRINTS PR00502 NUDIX hydrolase family signature 28 42 6.4E-7 T 12-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 VAPA_2c02490 ae4721c7022c46e895f33c84df560db6 146 Gene3D G3DSA:3.90.79.10 2 135 2.1E-23 T 12-10-2018 VAPA_1c22090 36405e481b6f1b9cb0d6e7171fa87e74 278 Gene3D G3DSA:1.10.3720.10 66 277 1.6E-25 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c22090 36405e481b6f1b9cb0d6e7171fa87e74 278 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 112 277 1.1E-10 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 VAPA_1c22090 36405e481b6f1b9cb0d6e7171fa87e74 278 SUPERFAMILY SSF161098 75 269 5.63E-23 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c37660 1669e6c41e0ab83a0c21a6f4b8df3fd5 90 Pfam PF09932 Uncharacterized conserved protein (DUF2164) 3 76 2.0E-26 T 12-10-2018 IPR018680 Protein of unknown function DUF2164 VAPA_1c09330 234d359fab992231c918d1118205fbf4 407 Pfam PF07690 Major Facilitator Superfamily 19 359 2.2E-42 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 VAPA_1c09330 234d359fab992231c918d1118205fbf4 407 SUPERFAMILY SSF103473 8 398 8.11E-62 T 12-10-2018 IPR036259 MFS transporter superfamily VAPA_1c09330 234d359fab992231c918d1118205fbf4 407 Gene3D G3DSA:1.20.1720.10 16 392 2.7E-86 T 12-10-2018 VAPA_1c09330 234d359fab992231c918d1118205fbf4 407 TIGRFAM TIGR00710 efflux_Bcr_CflA: drug resistance transporter, Bcr/CflA subfamily 13 389 6.5E-73 T 12-10-2018 IPR004812 Drug resistance transporter Bcr/CmlA subfamily GO:0006855|GO:0015238|GO:0016021 VAPA_2c06150 5af942ff0ad11ba3842ccbce8d070282 303 SUPERFAMILY SSF161098 94 285 8.5E-28 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_2c06150 5af942ff0ad11ba3842ccbce8d070282 303 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 10 65 5.9E-10 T 12-10-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain VAPA_2c06150 5af942ff0ad11ba3842ccbce8d070282 303 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 117 301 4.2E-32 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 VAPA_2c06150 5af942ff0ad11ba3842ccbce8d070282 303 Gene3D G3DSA:1.10.3720.10 89 295 1.6E-25 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c11610 0a6c7a7796fc48a59fbf7580a8a50ca4 354 Gene3D G3DSA:3.40.718.10 3 341 1.7E-98 T 12-10-2018 VAPA_1c11610 0a6c7a7796fc48a59fbf7580a8a50ca4 354 SUPERFAMILY SSF53659 13 340 2.03E-85 T 12-10-2018 VAPA_1c11610 0a6c7a7796fc48a59fbf7580a8a50ca4 354 Pfam PF04166 Pyridoxal phosphate biosynthetic protein PdxA 98 334 1.5E-79 T 12-10-2018 IPR005255 PdxA family GO:0051287|GO:0055114 KEGG: 00750+1.1.1.262 VAPA_1c16800 d1cda38ec67afd0d73947e6b7540ed6c 237 Pfam PF00005 ABC transporter 22 162 1.1E-28 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c16800 d1cda38ec67afd0d73947e6b7540ed6c 237 Gene3D G3DSA:3.40.50.300 2 235 3.4E-57 T 12-10-2018 VAPA_1c16800 d1cda38ec67afd0d73947e6b7540ed6c 237 SMART SM00382 31 200 1.9E-4 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c16800 d1cda38ec67afd0d73947e6b7540ed6c 237 SUPERFAMILY SSF52540 5 231 2.51E-55 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c16800 d1cda38ec67afd0d73947e6b7540ed6c 237 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_1c31200 c698bd820d7e7f929123d9b531a91c40 98 Gene3D G3DSA:1.10.10.1150 4 95 2.9E-24 T 12-10-2018 VAPA_1c31200 c698bd820d7e7f929123d9b531a91c40 98 TIGRFAM TIGR03859 PQQ_PqqD: coenzyme PQQ biosynthesis protein PqqD 15 94 8.4E-34 T 12-10-2018 IPR022479 Coenzyme PQQ synthesis D, bacteria GO:0018189|GO:0048038 VAPA_1c31200 c698bd820d7e7f929123d9b531a91c40 98 Pfam PF05402 Coenzyme PQQ synthesis protein D (PqqD) 31 93 4.0E-14 T 12-10-2018 IPR008792 Coenzyme PQQ synthesis D VAPA_1c31200 c698bd820d7e7f929123d9b531a91c40 98 Hamap MF_00655 Coenzyme PQQ synthesis protein D [pqqD]. 9 95 22.319 T 12-10-2018 IPR022479 Coenzyme PQQ synthesis D, bacteria GO:0018189|GO:0048038 VAPA_2c03680 182493a6c71adf61dab3b6b7b41a45c2 403 SUPERFAMILY SSF56601 14 393 2.41E-75 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like VAPA_2c03680 182493a6c71adf61dab3b6b7b41a45c2 403 Gene3D G3DSA:3.40.710.30 10 401 1.9E-128 T 12-10-2018 VAPA_2c03680 182493a6c71adf61dab3b6b7b41a45c2 403 Pfam PF00144 Beta-lactamase 23 391 1.3E-70 T 12-10-2018 IPR001466 Beta-lactamase-related VAPA_1c06040 5cf48501dd3c8650333706c8a3cdd696 630 TIGRFAM TIGR03359 VI_chp_6: type VI secretion protein, TIGR03359 family 6 629 1.6E-178 T 12-10-2018 IPR010272 Type VI secretion system, TssF-like VAPA_1c06040 5cf48501dd3c8650333706c8a3cdd696 630 Pfam PF05947 Type VI secretion system, TssF 6 628 7.6E-203 T 12-10-2018 IPR010272 Type VI secretion system, TssF-like VAPA_1c06040 5cf48501dd3c8650333706c8a3cdd696 630 PIRSF PIRSF028304 1 630 6.5E-170 T 12-10-2018 IPR010272 Type VI secretion system, TssF-like VAPA_1c51850 0a18017d03bad060cabfadafe216ecf1 32 Pfam PF09604 F subunit of K+-transporting ATPase (Potass_KdpF) 10 32 1.8E-4 T 12-10-2018 IPR011726 K+ transporting P-type ATPase, F subunit GO:0005886|GO:0008556|GO:0043462 VAPA_1c51850 0a18017d03bad060cabfadafe216ecf1 32 TIGRFAM TIGR02115 potass_kdpF: K+-transporting ATPase, F subunit 9 32 3.0E-7 T 12-10-2018 IPR011726 K+ transporting P-type ATPase, F subunit GO:0005886|GO:0008556|GO:0043462 VAPA_1c11600 a140fbd6b8940cd230391c7ad59ee644 109 Pfam PF05656 Protein of unknown function (DUF805) 14 107 1.6E-28 T 12-10-2018 IPR008523 Protein of unknown function DUF805 GO:0016021 VAPA_2c01190 49a12eb6b59ba7e69fb520c69d2477ca 144 Pfam PF14534 Domain of unknown function (DUF4440) 17 117 2.1E-6 T 12-10-2018 IPR027843 Domain of unknown function DUF4440 VAPA_2c01190 49a12eb6b59ba7e69fb520c69d2477ca 144 SUPERFAMILY SSF54427 3 121 1.95E-9 T 12-10-2018 IPR032710 NTF2-like domain superfamily VAPA_2c01190 49a12eb6b59ba7e69fb520c69d2477ca 144 Gene3D G3DSA:3.10.450.50 1 129 5.4E-9 T 12-10-2018 VAPA_2c12830 84fd4773f29aef9e738575bf84670ccb 119 SUPERFAMILY SSF143120 23 69 2.22E-6 T 12-10-2018 IPR036165 YefM-like superfamily VAPA_1c04880 e533cc7fa0330a22d3b8de6d3d60cbd5 159 Pfam PF02472 Biopolymer transport protein ExbD/TolR 25 147 3.1E-30 T 12-10-2018 IPR003400 Biopolymer transport protein ExbD/TolR GO:0022857|GO:0055085 VAPA_1c04880 e533cc7fa0330a22d3b8de6d3d60cbd5 159 Gene3D G3DSA:3.30.420.270 76 144 1.0E-17 T 12-10-2018 VAPA_2c10950 4559a24094b1699ed8356860e2cc175b 172 SMART SM00972 112 169 1.2E-17 T 12-10-2018 IPR007893 Spore coat protein U VAPA_2c10950 4559a24094b1699ed8356860e2cc175b 172 Pfam PF05229 Spore Coat Protein U domain 45 169 4.2E-24 T 12-10-2018 IPR007893 Spore coat protein U VAPA_2c00200 dfc5913460cf928d14e390d88deb9ec1 307 Pfam PF13020 Domain of unknown function (DUF3883) 204 287 5.9E-7 T 12-10-2018 IPR024975 Domain of unknown function DUF3883 VAPA_1c45320 3808e761167ba7f3d50dd12a3e628941 452 SUPERFAMILY SSF48452 154 258 5.55E-6 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 VAPA_1c45320 3808e761167ba7f3d50dd12a3e628941 452 Gene3D G3DSA:1.25.40.10 38 280 2.5E-6 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 VAPA_1c07920 6c35852b0b126ca0815ee6c45edb6219 183 Pfam PF13994 PgaD-like protein 47 161 5.0E-10 T 12-10-2018 IPR023829 Poly-beta-1,6-N-acetyl-D-glucosamine biosynthesis protein PgaD GO:0043709 VAPA_2c08890 29e0e3d532571ae13a6c77191db8dff1 316 SUPERFAMILY SSF54593 4 292 2.23E-41 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase VAPA_2c08890 29e0e3d532571ae13a6c77191db8dff1 316 Gene3D G3DSA:3.10.180.10 68 218 6.0E-100 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase VAPA_2c08890 29e0e3d532571ae13a6c77191db8dff1 316 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 155 273 2.0E-8 T 12-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain VAPA_2c08890 29e0e3d532571ae13a6c77191db8dff1 316 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 6 103 1.3E-7 T 12-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain VAPA_2c08890 29e0e3d532571ae13a6c77191db8dff1 316 Gene3D G3DSA:3.10.180.10 6 306 6.0E-100 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase VAPA_1c05790 0bebfc790e457d7c0b19ecefca62aa03 298 TIGRFAM TIGR02778 ligD_pol: DNA ligase D, polymerase domain 9 251 1.1E-86 T 12-10-2018 IPR014145 DNA ligase D, polymerase domain VAPA_1c05790 0bebfc790e457d7c0b19ecefca62aa03 298 SUPERFAMILY SSF56747 126 178 4.14E-5 T 12-10-2018 VAPA_1c05790 0bebfc790e457d7c0b19ecefca62aa03 298 Gene3D G3DSA:3.90.920.30 15 294 8.9E-98 T 12-10-2018 VAPA_1c23020 a19fd056207c45c4e460373d801e04df 175 Pfam PF05163 DinB family 1 163 6.5E-12 T 12-10-2018 IPR007837 DNA damage-inducible protein DinB VAPA_1c23020 a19fd056207c45c4e460373d801e04df 175 Gene3D G3DSA:1.20.120.450 4 156 1.8E-19 T 12-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes VAPA_1c23020 a19fd056207c45c4e460373d801e04df 175 SUPERFAMILY SSF109854 9 155 4.4E-21 T 12-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes VAPA_1c24120 b1b517cc273a0093057d5b8e6fe3fc7a 622 SUPERFAMILY SSF63829 280 580 2.03E-12 T 12-10-2018 VAPA_1c24120 b1b517cc273a0093057d5b8e6fe3fc7a 622 Pfam PF05787 Bacterial protein of unknown function (DUF839) 40 580 6.4E-175 T 12-10-2018 IPR008557 Protein of unknown function DUF839 VAPA_1c01980 8163fb03e0aa0fee4f0ba10d5133a791 222 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 34 216 4.1E-22 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 VAPA_1c01980 8163fb03e0aa0fee4f0ba10d5133a791 222 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 12 110 8.0E-31 T 12-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 VAPA_1c01980 8163fb03e0aa0fee4f0ba10d5133a791 222 SUPERFAMILY SSF161098 12 206 1.83E-46 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c01980 8163fb03e0aa0fee4f0ba10d5133a791 222 Gene3D G3DSA:1.10.3720.10 1 220 3.1E-61 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c15610 50f9881ff404b8125195154629b4f385 214 Gene3D G3DSA:1.20.58.220 12 214 1.3E-57 T 12-10-2018 IPR038078 PhoU-like domain superfamily VAPA_1c15610 50f9881ff404b8125195154629b4f385 214 SUPERFAMILY SSF109755 14 207 2.35E-5 T 12-10-2018 VAPA_1c15610 50f9881ff404b8125195154629b4f385 214 Pfam PF01865 Protein of unknown function DUF47 4 212 3.3E-32 T 12-10-2018 IPR018445 Putative phosphate transport regulator VAPA_1c10850 4f78976faae9424501a14a45147f45e5 419 Pfam PF07399 Putative Na+/H+ antiporter 6 419 5.2E-184 T 12-10-2018 IPR009978 Putative Na+/H+ antiporter VAPA_1c25900 49003ddf4d7f456d9469df57c192617f 191 Gene3D G3DSA:3.40.50.1820 1 177 9.1E-55 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c25900 49003ddf4d7f456d9469df57c192617f 191 SUPERFAMILY SSF53474 4 169 2.51E-31 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c25900 49003ddf4d7f456d9469df57c192617f 191 Pfam PF06821 Serine hydrolase 5 169 1.7E-61 T 12-10-2018 IPR010662 Putative hydrolase RBBP9/YdeN GO:0016787 VAPA_1c07840 2517c8678c8b16077336bcbfabbbed9d 230 Gene3D G3DSA:3.40.30.10 43 230 7.6E-41 T 12-10-2018 VAPA_1c07840 2517c8678c8b16077336bcbfabbbed9d 230 Pfam PF00578 AhpC/TSA family 53 179 8.1E-16 T 12-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 VAPA_1c07840 2517c8678c8b16077336bcbfabbbed9d 230 SUPERFAMILY SSF52833 50 229 2.28E-31 T 12-10-2018 IPR036249 Thioredoxin-like superfamily VAPA_2c07720 c2f04a6e1787df6f9b9fa4c8f26ea6d9 552 Gene3D G3DSA:2.40.160.50 175 552 5.3E-82 T 12-10-2018 VAPA_2c07720 c2f04a6e1787df6f9b9fa4c8f26ea6d9 552 Pfam PF08479 POTRA domain, ShlB-type 70 143 3.9E-22 T 12-10-2018 IPR013686 Polypeptide-transport-associated, ShlB-type VAPA_2c07720 c2f04a6e1787df6f9b9fa4c8f26ea6d9 552 Pfam PF03865 Haemolysin secretion/activation protein ShlB/FhaC/HecB 204 514 1.1E-30 T 12-10-2018 IPR005565 Haemolysin activator HlyB, C-terminal VAPA_2c07720 c2f04a6e1787df6f9b9fa4c8f26ea6d9 552 Gene3D G3DSA:3.10.20.310 59 143 8.4E-23 T 12-10-2018 VAPA_1c33700 67f05a87bd95c132fed21e7d4a9bec10 212 TIGRFAM TIGR02428 pcaJ_scoB_fam: 3-oxoacid CoA-transferase, B subunit 3 211 5.7E-94 T 12-10-2018 IPR012791 3-oxoacid CoA-transferase, subunit B GO:0008410 Reactome: R-HSA-77108 VAPA_1c33700 67f05a87bd95c132fed21e7d4a9bec10 212 SMART SM00882 6 205 1.3E-79 T 12-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 VAPA_1c33700 67f05a87bd95c132fed21e7d4a9bec10 212 SUPERFAMILY SSF100950 3 211 4.95E-69 T 12-10-2018 IPR037171 NagB/RpiA transferase-like VAPA_1c33700 67f05a87bd95c132fed21e7d4a9bec10 212 Gene3D G3DSA:3.40.1080.10 3 211 3.8E-96 T 12-10-2018 VAPA_1c33700 67f05a87bd95c132fed21e7d4a9bec10 212 Pfam PF01144 Coenzyme A transferase 7 203 2.1E-39 T 12-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 VAPA_1c09960 b367301c3a0ff7efdcdad7e7d2a7e01d 372 Pfam PF00793 DAHP synthetase I family 62 359 1.3E-102 T 12-10-2018 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 VAPA_1c09960 b367301c3a0ff7efdcdad7e7d2a7e01d 372 PIRSF PIRSF001361 12 372 2.0E-157 T 12-10-2018 IPR006219 DHAP synthase, class 1 GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 VAPA_1c09960 b367301c3a0ff7efdcdad7e7d2a7e01d 372 Gene3D G3DSA:3.20.20.70 18 372 2.5E-158 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 VAPA_1c09960 b367301c3a0ff7efdcdad7e7d2a7e01d 372 TIGRFAM TIGR00034 aroFGH: 3-deoxy-7-phosphoheptulonate synthase 23 371 5.7E-162 T 12-10-2018 IPR006219 DHAP synthase, class 1 GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 VAPA_1c09960 b367301c3a0ff7efdcdad7e7d2a7e01d 372 SUPERFAMILY SSF51569 25 370 1.57E-130 T 12-10-2018 VAPA_1c13280 302807b52195d87190d4051b689a3c28 353 Pfam PF00005 ABC transporter 28 167 1.5E-32 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c13280 302807b52195d87190d4051b689a3c28 353 SMART SM00382 33 225 2.4E-18 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c13280 302807b52195d87190d4051b689a3c28 353 Pfam PF08402 TOBE domain 277 345 3.1E-11 T 12-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 VAPA_1c13280 302807b52195d87190d4051b689a3c28 353 SUPERFAMILY SSF50331 251 346 1.36E-14 T 12-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal VAPA_1c13280 302807b52195d87190d4051b689a3c28 353 Gene3D G3DSA:3.40.50.300 8 263 1.7E-70 T 12-10-2018 VAPA_1c13280 302807b52195d87190d4051b689a3c28 353 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_1c13280 302807b52195d87190d4051b689a3c28 353 SUPERFAMILY SSF52540 8 246 3.25E-78 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c21600 9d289fd30747590c80a084eee7090850 364 Pfam PF00583 Acetyltransferase (GNAT) family 49 137 1.4E-4 T 12-10-2018 IPR000182 GNAT domain VAPA_1c21600 9d289fd30747590c80a084eee7090850 364 Gene3D G3DSA:3.40.630.30 11 345 1.3E-56 T 12-10-2018 VAPA_1c21600 9d289fd30747590c80a084eee7090850 364 SUPERFAMILY SSF55729 22 134 2.96E-9 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase VAPA_1c21600 9d289fd30747590c80a084eee7090850 364 SUPERFAMILY SSF55729 212 341 1.75E-13 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase VAPA_1c36880 1037657412eb665eaae95632fe1b2d3a 209 Pfam PF01810 LysE type translocator 14 201 2.7E-28 T 12-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 VAPA_1c49480 722fc7c5acc913b598c98275ccdf0c2d 259 SUPERFAMILY SSF46894 186 257 1.5E-14 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 VAPA_1c49480 722fc7c5acc913b598c98275ccdf0c2d 259 SMART SM00421 200 257 8.3E-10 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_1c49480 722fc7c5acc913b598c98275ccdf0c2d 259 Pfam PF00196 Bacterial regulatory proteins, luxR family 202 256 5.2E-11 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_1c49480 722fc7c5acc913b598c98275ccdf0c2d 259 Gene3D G3DSA:1.10.10.10 195 258 6.9E-14 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c49480 722fc7c5acc913b598c98275ccdf0c2d 259 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 217 233 4.1E-7 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_1c49480 722fc7c5acc913b598c98275ccdf0c2d 259 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 233 245 4.1E-7 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_1c49480 722fc7c5acc913b598c98275ccdf0c2d 259 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 203 217 4.1E-7 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 VAPA_1c20730 32ed63464e03f9750ff26498332146ed 990 Gene3D G3DSA:3.10.560.10 164 225 4.8E-9 T 12-10-2018 VAPA_1c20730 32ed63464e03f9750ff26498332146ed 990 Pfam PF06082 Exopolysaccharide biosynthesis protein YbjH 289 958 1.5E-229 T 12-10-2018 IPR010344 Exopolysaccharide biosynthesis protein YbjH VAPA_1c20730 32ed63464e03f9750ff26498332146ed 990 Pfam PF06251 Capsule biosynthesis GfcC 80 227 8.6E-11 T 12-10-2018 IPR010425 Domain of unknown function DUF1017 VAPA_1c12870 19d7f1bc07aa6f80bbc7135ea38d1241 537 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 69 231 2.4E-13 T 12-10-2018 IPR038731 Glycosyltransferase RgtA/B/C/D-like VAPA_2c08630 b1cd195be27fd9a84b872d58a69f6cc5 305 Gene3D G3DSA:3.60.15.10 12 305 3.6E-78 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like VAPA_2c08630 b1cd195be27fd9a84b872d58a69f6cc5 305 Pfam PF00753 Metallo-beta-lactamase superfamily 73 280 1.6E-22 T 12-10-2018 IPR001279 Metallo-beta-lactamase VAPA_2c08630 b1cd195be27fd9a84b872d58a69f6cc5 305 SUPERFAMILY SSF56281 18 302 1.57E-46 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like VAPA_2c08630 b1cd195be27fd9a84b872d58a69f6cc5 305 SMART SM00849 73 280 2.7E-21 T 12-10-2018 IPR001279 Metallo-beta-lactamase VAPA_1c05660 29272d36ed24ee4725782a9c29902940 498 Gene3D G3DSA:1.20.1720.10 37 254 2.7E-28 T 12-10-2018 VAPA_1c05660 29272d36ed24ee4725782a9c29902940 498 Pfam PF07690 Major Facilitator Superfamily 43 438 6.1E-28 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 VAPA_1c05660 29272d36ed24ee4725782a9c29902940 498 Gene3D G3DSA:1.20.1250.20 287 490 4.1E-9 T 12-10-2018 VAPA_1c05660 29272d36ed24ee4725782a9c29902940 498 SUPERFAMILY SSF103473 15 483 1.27E-37 T 12-10-2018 IPR036259 MFS transporter superfamily VAPA_1c46480 92939d78595457481bffdf092d081e06 1360 Pfam PF04357 TamB, inner membrane protein subunit of TAM complex 1003 1359 8.1E-61 T 12-10-2018 IPR007452 Translocation and assembly module TamB VAPA_1c33270 13c2fe8db831bea946c2cfe9df45b5b1 746 SMART SM01008 28 140 5.1E-31 T 12-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead VAPA_1c33270 13c2fe8db831bea946c2cfe9df45b5b1 746 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 29 138 1.1E-19 T 12-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead VAPA_1c33270 13c2fe8db831bea946c2cfe9df45b5b1 746 Gene3D G3DSA:3.30.365.10 194 287 1.1E-60 T 12-10-2018 VAPA_1c33270 13c2fe8db831bea946c2cfe9df45b5b1 746 Gene3D G3DSA:3.90.1170.50 4 140 5.8E-28 T 12-10-2018 VAPA_1c33270 13c2fe8db831bea946c2cfe9df45b5b1 746 SUPERFAMILY SSF56003 133 745 1.44E-143 T 12-10-2018 IPR037165 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain superfamily GO:0016491|GO:0055114 VAPA_1c33270 13c2fe8db831bea946c2cfe9df45b5b1 746 Gene3D G3DSA:3.30.365.10 452 576 6.2E-73 T 12-10-2018 VAPA_1c33270 13c2fe8db831bea946c2cfe9df45b5b1 746 Gene3D G3DSA:3.30.365.10 441 744 6.2E-73 T 12-10-2018 VAPA_1c33270 13c2fe8db831bea946c2cfe9df45b5b1 746 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 167 686 6.4E-108 T 12-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 VAPA_1c33270 13c2fe8db831bea946c2cfe9df45b5b1 746 Gene3D G3DSA:3.30.365.10 170 392 1.1E-60 T 12-10-2018 VAPA_1c33270 13c2fe8db831bea946c2cfe9df45b5b1 746 SUPERFAMILY SSF54665 17 147 2.36E-31 T 12-10-2018 IPR036856 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead superfamily VAPA_1c48820 0034e306b350507058ad7293c03cab68 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 142 150 4.8E-11 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c48820 0034e306b350507058ad7293c03cab68 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 86 97 4.8E-11 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c48820 0034e306b350507058ad7293c03cab68 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 163 182 4.8E-11 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c48820 0034e306b350507058ad7293c03cab68 256 SUPERFAMILY SSF51735 10 253 1.73E-72 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c48820 0034e306b350507058ad7293c03cab68 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 184 201 9.1E-37 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c48820 0034e306b350507058ad7293c03cab68 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 13 30 9.1E-37 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c48820 0034e306b350507058ad7293c03cab68 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 216 236 9.1E-37 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c48820 0034e306b350507058ad7293c03cab68 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 86 97 9.1E-37 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c48820 0034e306b350507058ad7293c03cab68 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 163 182 9.1E-37 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c48820 0034e306b350507058ad7293c03cab68 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 136 152 9.1E-37 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c48820 0034e306b350507058ad7293c03cab68 256 Gene3D G3DSA:3.40.50.720 4 253 1.7E-75 T 12-10-2018 VAPA_1c48820 0034e306b350507058ad7293c03cab68 256 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 20 253 1.6E-53 T 12-10-2018 VAPA_1c28850 3bb29da193198ff7c7f807f5f71da507 209 Hamap MF_01218_B Uracil phosphoribosyltransferase [upp]. 3 209 44.509 T 12-10-2018 IPR034332 Uracil phosphoribosyltransferase, bacterial-type KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 VAPA_1c28850 3bb29da193198ff7c7f807f5f71da507 209 Gene3D G3DSA:3.40.50.2020 1 209 3.5E-80 T 12-10-2018 VAPA_1c28850 3bb29da193198ff7c7f807f5f71da507 209 TIGRFAM TIGR01091 upp: uracil phosphoribosyltransferase 3 209 9.9E-84 T 12-10-2018 IPR005765 Uracil phosphoribosyl transferase GO:0004845|GO:0006223 KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 VAPA_1c28850 3bb29da193198ff7c7f807f5f71da507 209 Pfam PF14681 Uracil phosphoribosyltransferase 7 208 2.4E-72 T 12-10-2018 VAPA_1c28850 3bb29da193198ff7c7f807f5f71da507 209 SUPERFAMILY SSF53271 3 207 3.8E-72 T 12-10-2018 IPR029057 Phosphoribosyltransferase-like VAPA_1c37250 ca774e620ad4da4b9ed4cb89f58b1bd6 444 Pfam PF00202 Aminotransferase class-III 19 432 2.2E-96 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 VAPA_1c37250 ca774e620ad4da4b9ed4cb89f58b1bd6 444 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 237 274 - T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 VAPA_1c37250 ca774e620ad4da4b9ed4cb89f58b1bd6 444 Gene3D G3DSA:3.40.640.10 48 326 6.7E-152 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 VAPA_1c37250 ca774e620ad4da4b9ed4cb89f58b1bd6 444 SUPERFAMILY SSF53383 5 436 4.43E-120 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase VAPA_1c37250 ca774e620ad4da4b9ed4cb89f58b1bd6 444 Gene3D G3DSA:3.90.1150.10 19 435 6.7E-152 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 VAPA_1c37250 ca774e620ad4da4b9ed4cb89f58b1bd6 444 PIRSF PIRSF000521 16 380 9.4E-30 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 VAPA_1c12560 790b70f4d2b85d877a38be6b7a1620f8 1031 Gene3D G3DSA:3.10.560.10 169 231 1.3E-9 T 12-10-2018 VAPA_1c12560 790b70f4d2b85d877a38be6b7a1620f8 1031 Pfam PF06251 Capsule biosynthesis GfcC 82 231 1.6E-10 T 12-10-2018 IPR010425 Domain of unknown function DUF1017 VAPA_1c12560 790b70f4d2b85d877a38be6b7a1620f8 1031 Pfam PF06082 Exopolysaccharide biosynthesis protein YbjH 320 1001 3.2E-231 T 12-10-2018 IPR010344 Exopolysaccharide biosynthesis protein YbjH VAPA_1c17300 62068d53d2d4f243b47b3019989136f9 531 Pfam PF10119 Predicted methyltransferase regulatory domain 220 302 1.0E-27 T 12-10-2018 IPR018773 Methyltransferase regulatory domain, predicted VAPA_1c17300 62068d53d2d4f243b47b3019989136f9 531 Pfam PF13649 Methyltransferase domain 50 147 2.8E-11 T 12-10-2018 VAPA_1c17300 62068d53d2d4f243b47b3019989136f9 531 SUPERFAMILY SSF53335 27 161 1.39E-26 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase VAPA_1c17300 62068d53d2d4f243b47b3019989136f9 531 Gene3D G3DSA:3.40.50.150 25 182 9.3E-22 T 12-10-2018 VAPA_1c42900 bc50dd473c72bbd3532e13ee219be68a 293 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 90 292 9.4E-21 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 VAPA_1c42900 bc50dd473c72bbd3532e13ee219be68a 293 Gene3D G3DSA:1.10.3720.10 51 292 3.5E-62 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c42900 bc50dd473c72bbd3532e13ee219be68a 293 SUPERFAMILY SSF161098 55 282 1.03E-52 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_2c07830 d1d7004ac678b20f1677251f965923b2 262 Pfam PF09836 Putative DNA-binding domain 7 96 2.0E-20 T 12-10-2018 IPR018640 Putative DNA-binding domain, bacteria VAPA_1c28980 9c1d9013e5dd1e74d8125a6301c882f1 304 SUPERFAMILY SSF53474 14 279 1.16E-37 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c28980 9c1d9013e5dd1e74d8125a6301c882f1 304 Pfam PF07859 alpha/beta hydrolase fold 62 180 1.7E-14 T 12-10-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0016787 VAPA_1c28980 9c1d9013e5dd1e74d8125a6301c882f1 304 Gene3D G3DSA:3.40.50.1820 17 262 4.0E-43 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c11640 75f73966909320a5880fc4202d5e2cdd 436 Gene3D G3DSA:3.40.190.10 137 422 2.7E-144 T 12-10-2018 VAPA_1c11640 75f73966909320a5880fc4202d5e2cdd 436 SUPERFAMILY SSF53850 22 431 8.89E-74 T 12-10-2018 VAPA_1c11640 75f73966909320a5880fc4202d5e2cdd 436 Gene3D G3DSA:3.40.190.10 41 393 2.7E-144 T 12-10-2018 VAPA_1c11640 75f73966909320a5880fc4202d5e2cdd 436 Pfam PF01547 Bacterial extracellular solute-binding protein 44 326 1.6E-42 T 12-10-2018 IPR006059 Bacterial extracellular solute-binding protein VAPA_1c15640 3b5e587df4ffffd5595c284d8321b21e 174 SUPERFAMILY SSF55729 4 167 9.43E-33 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase VAPA_1c15640 3b5e587df4ffffd5595c284d8321b21e 174 Gene3D G3DSA:3.40.630.30 1 174 2.2E-52 T 12-10-2018 VAPA_1c15640 3b5e587df4ffffd5595c284d8321b21e 174 Pfam PF13420 Acetyltransferase (GNAT) domain 5 159 6.3E-26 T 12-10-2018 VAPA_1c35380 c3421ded61836009cee6ca846e80db0e 189 Pfam PF13649 Methyltransferase domain 30 109 2.1E-9 T 12-10-2018 VAPA_1c35380 c3421ded61836009cee6ca846e80db0e 189 Gene3D G3DSA:3.40.50.150 4 167 6.5E-25 T 12-10-2018 VAPA_1c35380 c3421ded61836009cee6ca846e80db0e 189 SUPERFAMILY SSF53335 12 154 1.15E-24 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase VAPA_1c16570 c7c23a3bfe1f344cb29f3ac501052729 190 Pfam PF11736 Protein of unknown function (DUF3299) 45 183 1.9E-41 T 12-10-2018 IPR021727 Protein of unknown function DUF3299 VAPA_1c16570 c7c23a3bfe1f344cb29f3ac501052729 190 Gene3D G3DSA:2.40.50.870 38 189 1.6E-51 T 12-10-2018 VAPA_1c51790 4f9a9c273515d8c303c256991a8c058b 376 Gene3D G3DSA:3.90.180.10 4 371 2.3E-154 T 12-10-2018 VAPA_1c51790 4f9a9c273515d8c303c256991a8c058b 376 SUPERFAMILY SSF51735 146 258 1.27E-12 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c51790 4f9a9c273515d8c303c256991a8c058b 376 Gene3D G3DSA:3.40.50.720 150 337 2.3E-154 T 12-10-2018 VAPA_1c51790 4f9a9c273515d8c303c256991a8c058b 376 SUPERFAMILY SSF50129 14 182 3.03E-21 T 12-10-2018 IPR011032 GroES-like superfamily VAPA_1c51790 4f9a9c273515d8c303c256991a8c058b 376 SMART SM00829 13 308 0.0043 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 VAPA_1c21340 31f4d192b3224ae3d0a753b4f10a9d9d 164 Gene3D G3DSA:1.20.120.520 2 155 5.6E-15 T 12-10-2018 VAPA_1c21340 31f4d192b3224ae3d0a753b4f10a9d9d 164 Pfam PF01814 Hemerythrin HHE cation binding domain 15 132 2.6E-14 T 12-10-2018 IPR012312 Haemerythrin-like Reactome: R-HSA-390471|Reactome: R-HSA-8951664|Reactome: R-HSA-917937|Reactome: R-HSA-983168 VAPA_1c36610 953c0b6e4c0f76df81aea84ab7b33e44 189 SUPERFAMILY SSF55781 84 169 3.58E-6 T 12-10-2018 VAPA_1c36610 953c0b6e4c0f76df81aea84ab7b33e44 189 Pfam PF01590 GAF domain 65 161 8.0E-5 T 12-10-2018 IPR003018 GAF domain GO:0005515 VAPA_1c36610 953c0b6e4c0f76df81aea84ab7b33e44 189 Gene3D G3DSA:3.30.450.40 58 176 1.4E-6 T 12-10-2018 IPR029016 GAF-like domain superfamily VAPA_2c09820 3d52b8ef9e7e5135565356233a0d85c9 260 Gene3D G3DSA:3.30.450.40 85 254 6.1E-33 T 12-10-2018 IPR029016 GAF-like domain superfamily VAPA_2c09820 3d52b8ef9e7e5135565356233a0d85c9 260 Gene3D G3DSA:1.10.10.10 2 80 2.3E-19 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_2c09820 3d52b8ef9e7e5135565356233a0d85c9 260 SUPERFAMILY SSF55781 70 256 3.6E-32 T 12-10-2018 VAPA_2c09820 3d52b8ef9e7e5135565356233a0d85c9 260 SMART SM00346 12 102 7.0E-15 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 VAPA_2c09820 3d52b8ef9e7e5135565356233a0d85c9 260 SUPERFAMILY SSF46785 14 84 7.12E-12 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_2c09820 3d52b8ef9e7e5135565356233a0d85c9 260 Pfam PF09339 IclR helix-turn-helix domain 15 64 1.6E-12 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 VAPA_2c09820 3d52b8ef9e7e5135565356233a0d85c9 260 Pfam PF01614 Bacterial transcriptional regulator 135 253 3.1E-10 T 12-10-2018 IPR014757 Transcription regulator IclR, C-terminal VAPA_1c06680 62ebe2ad150daf9379ef3bbe209932c8 204 Gene3D G3DSA:3.40.50.1820 1 200 4.6E-29 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c06680 62ebe2ad150daf9379ef3bbe209932c8 204 Pfam PF02230 Phospholipase/Carboxylesterase 5 199 6.2E-36 T 12-10-2018 IPR003140 Phospholipase/carboxylesterase/thioesterase GO:0016787 VAPA_1c06680 62ebe2ad150daf9379ef3bbe209932c8 204 SUPERFAMILY SSF53474 3 197 9.45E-27 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c13990 e4422c4931fecf9f330843b2b5746093 187 SUPERFAMILY SSF159275 3 183 1.28E-50 T 12-10-2018 VAPA_1c13990 e4422c4931fecf9f330843b2b5746093 187 Pfam PF06475 Putative glycolipid-binding 7 184 4.2E-46 T 12-10-2018 IPR009467 Putative glycolipid-binding protein VAPA_2c02250 e65099c86d18f4723fd4562848efcd8b 278 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 139 155 4.2E-46 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c02250 e65099c86d18f4723fd4562848efcd8b 278 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 186 203 4.2E-46 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c02250 e65099c86d18f4723fd4562848efcd8b 278 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 220 240 4.2E-46 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c02250 e65099c86d18f4723fd4562848efcd8b 278 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 92 103 4.2E-46 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c02250 e65099c86d18f4723fd4562848efcd8b 278 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 165 184 4.2E-46 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c02250 e65099c86d18f4723fd4562848efcd8b 278 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 19 36 4.2E-46 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c02250 e65099c86d18f4723fd4562848efcd8b 278 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 152 180 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 VAPA_2c02250 e65099c86d18f4723fd4562848efcd8b 278 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 92 103 2.6E-11 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c02250 e65099c86d18f4723fd4562848efcd8b 278 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 145 153 2.6E-11 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c02250 e65099c86d18f4723fd4562848efcd8b 278 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 165 184 2.6E-11 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_2c02250 e65099c86d18f4723fd4562848efcd8b 278 Gene3D G3DSA:3.40.50.720 1 261 1.9E-86 T 12-10-2018 VAPA_2c02250 e65099c86d18f4723fd4562848efcd8b 278 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 24 256 8.5E-70 T 12-10-2018 VAPA_2c02250 e65099c86d18f4723fd4562848efcd8b 278 SUPERFAMILY SSF51735 18 256 7.74E-85 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c16310 6ff0c0cd2f27cdf077898ea7ae00ddfa 220 Gene3D G3DSA:2.40.160.20 29 220 3.2E-49 T 12-10-2018 VAPA_1c16310 6ff0c0cd2f27cdf077898ea7ae00ddfa 220 SUPERFAMILY SSF56925 31 220 1.99E-27 T 12-10-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel VAPA_1c16310 6ff0c0cd2f27cdf077898ea7ae00ddfa 220 Pfam PF03922 OmpW family 31 220 1.2E-42 T 12-10-2018 IPR005618 Outer membrane protein, OmpW GO:0019867 VAPA_1c30600 b07a6a7e63af092f1250312672b10f44 355 Pfam PF02653 Branched-chain amino acid transport system / permease component 42 322 2.4E-35 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 VAPA_2c01310 5bc76b1c30b0f24fb7b7a3140589749c 323 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 48 319 2.1E-86 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_2c01310 5bc76b1c30b0f24fb7b7a3140589749c 323 SUPERFAMILY SSF53850 111 282 1.48E-11 T 12-10-2018 VAPA_2c01310 5bc76b1c30b0f24fb7b7a3140589749c 323 PIRSF PIRSF017082 1 323 2.8E-77 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_2c01310 5bc76b1c30b0f24fb7b7a3140589749c 323 Gene3D G3DSA:3.40.190.150 27 313 1.5E-114 T 12-10-2018 VAPA_2c01310 5bc76b1c30b0f24fb7b7a3140589749c 323 Gene3D G3DSA:3.40.190.10 125 248 1.5E-114 T 12-10-2018 VAPA_2c09420 eee34a9575e1681341ed08ab451ae317 505 Pfam PF02321 Outer membrane efflux protein 305 490 8.7E-24 T 12-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 VAPA_2c09420 eee34a9575e1681341ed08ab451ae317 505 Pfam PF02321 Outer membrane efflux protein 89 279 3.4E-24 T 12-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 VAPA_2c09420 eee34a9575e1681341ed08ab451ae317 505 SUPERFAMILY SSF56954 13 494 3.14E-98 T 12-10-2018 VAPA_2c09420 eee34a9575e1681341ed08ab451ae317 505 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 20 492 3.9E-105 T 12-10-2018 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0016020|GO:0022857|GO:0055085 VAPA_2c09420 eee34a9575e1681341ed08ab451ae317 505 Gene3D G3DSA:2.20.200.10 124 381 1.3E-125 T 12-10-2018 VAPA_2c09420 eee34a9575e1681341ed08ab451ae317 505 Gene3D G3DSA:1.20.1600.10 77 493 1.3E-125 T 12-10-2018 VAPA_1c38780 4d9236b6916fc16347db8c93e15205b2 284 Gene3D G3DSA:1.20.5.170 215 284 1.5E-5 T 12-10-2018 VAPA_1c11070 a0944f88915466269ecd35d105119f7e 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 144 152 3.6E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c11070 a0944f88915466269ecd35d105119f7e 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 93 104 3.6E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c11070 a0944f88915466269ecd35d105119f7e 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 164 183 3.6E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c11070 a0944f88915466269ecd35d105119f7e 259 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 19 257 1.4E-50 T 12-10-2018 VAPA_1c11070 a0944f88915466269ecd35d105119f7e 259 SUPERFAMILY SSF51735 11 258 5.59E-68 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c11070 a0944f88915466269ecd35d105119f7e 259 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 11 195 0.0075 T 12-10-2018 VAPA_1c11070 a0944f88915466269ecd35d105119f7e 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 221 241 1.2E-33 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c11070 a0944f88915466269ecd35d105119f7e 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 164 183 1.2E-33 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c11070 a0944f88915466269ecd35d105119f7e 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 185 202 1.2E-33 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c11070 a0944f88915466269ecd35d105119f7e 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 12 29 1.2E-33 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c11070 a0944f88915466269ecd35d105119f7e 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 138 154 1.2E-33 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c11070 a0944f88915466269ecd35d105119f7e 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 93 104 1.2E-33 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c11070 a0944f88915466269ecd35d105119f7e 259 Gene3D G3DSA:3.40.50.720 8 259 1.9E-71 T 12-10-2018 VAPA_1c33630 17dd00c5f9c068e05262635a5c233c23 371 Gene3D G3DSA:3.90.226.10 4 371 1.3E-124 T 12-10-2018 VAPA_1c33630 17dd00c5f9c068e05262635a5c233c23 371 SUPERFAMILY SSF52096 16 343 3.45E-58 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily VAPA_1c33630 17dd00c5f9c068e05262635a5c233c23 371 Pfam PF16113 Enoyl-CoA hydratase/isomerase 20 356 1.1E-114 T 12-10-2018 IPR032259 Enoyl-CoA hydratase/isomerase, HIBYL-CoA-H type GO:0003860 Reactome: R-HSA-70895 VAPA_1c15020 f7c60f129262edfef5fcf2c715f805b2 420 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 184 197 - T 12-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 VAPA_1c15020 f7c60f129262edfef5fcf2c715f805b2 420 Pfam PF00012 Hsp70 protein 96 231 5.4E-10 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 VAPA_1c15020 f7c60f129262edfef5fcf2c715f805b2 420 Pfam PF00012 Hsp70 protein 299 395 3.4E-5 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 VAPA_1c15020 f7c60f129262edfef5fcf2c715f805b2 420 SUPERFAMILY SSF53067 179 417 1.79E-32 T 12-10-2018 VAPA_1c15020 f7c60f129262edfef5fcf2c715f805b2 420 SUPERFAMILY SSF53067 9 175 1.59E-30 T 12-10-2018 VAPA_1c02770 243887566fb22191343cc8a484234678 432 TIGRFAM TIGR00836 amt: ammonium transporter 1 430 7.6E-126 T 12-10-2018 IPR001905 Ammonium transporter GO:0008519|GO:0016020|GO:0072488 VAPA_1c02770 243887566fb22191343cc8a484234678 432 Gene3D G3DSA:1.10.3430.10 1 432 2.0E-126 T 12-10-2018 IPR029020 Ammonium/urea transporter VAPA_1c02770 243887566fb22191343cc8a484234678 432 Pfam PF00909 Ammonium Transporter Family 1 430 2.1E-113 T 12-10-2018 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 VAPA_1c02770 243887566fb22191343cc8a484234678 432 SUPERFAMILY SSF111352 1 411 1.26E-115 T 12-10-2018 VAPA_1c02770 243887566fb22191343cc8a484234678 432 ProSitePatterns PS01219 Ammonium transporters signature. 178 203 - T 12-10-2018 IPR018047 Ammonium transporter, conserved site GO:0008519|GO:0016020|GO:0072488 VAPA_1c43240 73a54cf3bbfe6d2d841b0fc664d976f5 105 Pfam PF02049 Flagellar hook-basal body complex protein FliE 23 104 2.0E-26 T 12-10-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 VAPA_1c43240 73a54cf3bbfe6d2d841b0fc664d976f5 105 Hamap MF_00724 Flagellar hook-basal body complex protein FliE [fliE]. 4 105 16.678 T 12-10-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 VAPA_1c43240 73a54cf3bbfe6d2d841b0fc664d976f5 105 PRINTS PR01006 Flagellar hook-basal body complex protein FliE signature 90 103 3.3E-15 T 12-10-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 VAPA_1c43240 73a54cf3bbfe6d2d841b0fc664d976f5 105 PRINTS PR01006 Flagellar hook-basal body complex protein FliE signature 34 50 3.3E-15 T 12-10-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 VAPA_1c43240 73a54cf3bbfe6d2d841b0fc664d976f5 105 PRINTS PR01006 Flagellar hook-basal body complex protein FliE signature 69 85 3.3E-15 T 12-10-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 VAPA_1c43240 73a54cf3bbfe6d2d841b0fc664d976f5 105 TIGRFAM TIGR00205 fliE: flagellar hook-basal body complex protein FliE 6 103 2.1E-23 T 12-10-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 VAPA_1c25420 b2c016fb686996d4b2b2f62884d9ea7a 131 Pfam PF06983 3-demethylubiquinone-9 3-methyltransferase 4 126 4.3E-7 T 12-10-2018 IPR028973 PhnB-like VAPA_1c25420 b2c016fb686996d4b2b2f62884d9ea7a 131 Gene3D G3DSA:3.10.180.10 7 131 1.7E-30 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase VAPA_1c25420 b2c016fb686996d4b2b2f62884d9ea7a 131 SUPERFAMILY SSF54593 1 129 3.48E-25 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase VAPA_1c36110 22e8ca22b8ef513f84b03e5863baa978 358 Hamap MF_01350 NAD(P)H-quinone oxidoreductase subunit 1, chloroplastic [ndhA]. 24 353 24.613 T 12-10-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VAPA_1c36110 22e8ca22b8ef513f84b03e5863baa978 358 Pfam PF00146 NADH dehydrogenase 30 346 4.2E-124 T 12-10-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VAPA_1c36110 22e8ca22b8ef513f84b03e5863baa978 358 ProSitePatterns PS00667 Respiratory-chain NADH dehydrogenase subunit 1 signature 1. 70 85 - T 12-10-2018 IPR018086 NADH:ubiquinone oxidoreductase, subunit 1, conserved site GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VAPA_1c36110 22e8ca22b8ef513f84b03e5863baa978 358 ProSitePatterns PS00668 Respiratory-chain NADH dehydrogenase subunit 1 signature 2. 236 249 - T 12-10-2018 IPR018086 NADH:ubiquinone oxidoreductase, subunit 1, conserved site GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VAPA_1c49830 4cea8511390611cfc1e5f49f38659ad5 253 Pfam PF04972 BON domain 65 120 1.5E-9 T 12-10-2018 IPR007055 BON domain VAPA_1c49830 4cea8511390611cfc1e5f49f38659ad5 253 Pfam PF04972 BON domain 134 196 7.4E-11 T 12-10-2018 IPR007055 BON domain VAPA_1c49830 4cea8511390611cfc1e5f49f38659ad5 253 SMART SM00749 57 120 59.0 T 12-10-2018 IPR014004 Transport-associated and nodulation domain, bacteria VAPA_1c49830 4cea8511390611cfc1e5f49f38659ad5 253 SMART SM00749 135 198 2.0E-4 T 12-10-2018 IPR014004 Transport-associated and nodulation domain, bacteria VAPA_1c12190 9261c361ce1835db1768b93a6fb814c4 315 SMART SM00382 39 219 2.0E-14 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c12190 9261c361ce1835db1768b93a6fb814c4 315 ProSitePatterns PS00211 ABC transporters family signature. 144 158 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_1c12190 9261c361ce1835db1768b93a6fb814c4 315 Gene3D G3DSA:3.40.50.300 1 246 8.4E-67 T 12-10-2018 VAPA_1c12190 9261c361ce1835db1768b93a6fb814c4 315 SUPERFAMILY SSF52540 3 238 2.77E-62 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c12190 9261c361ce1835db1768b93a6fb814c4 315 Pfam PF00005 ABC transporter 31 172 3.2E-34 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c39190 a7aac04bf4a5b5f4d331f328bc1f9739 1001 Gene3D G3DSA:3.40.710.10 787 986 6.2E-15 T 12-10-2018 VAPA_1c39190 a7aac04bf4a5b5f4d331f328bc1f9739 1001 Gene3D G3DSA:1.10.3810.10 120 322 1.6E-6 T 12-10-2018 IPR036950 Penicillin binding protein transglycosylase domain KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 VAPA_1c39190 a7aac04bf4a5b5f4d331f328bc1f9739 1001 Pfam PF00912 Transglycosylase 133 326 7.8E-24 T 12-10-2018 IPR001264 Glycosyl transferase, family 51 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 VAPA_1c39190 a7aac04bf4a5b5f4d331f328bc1f9739 1001 SUPERFAMILY SSF56601 554 993 5.0E-28 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like VAPA_1c39190 a7aac04bf4a5b5f4d331f328bc1f9739 1001 Pfam PF00905 Penicillin binding protein transpeptidase domain 822 929 1.9E-6 T 12-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 VAPA_1c39190 a7aac04bf4a5b5f4d331f328bc1f9739 1001 SUPERFAMILY SSF53955 136 287 7.87E-10 T 12-10-2018 IPR023346 Lysozyme-like domain superfamily VAPA_1c50450 521649f8591d1dd40fae543ac3f1d64c 235 SUPERFAMILY SSF48317 37 220 1.02E-9 T 12-10-2018 IPR036938 Phosphatidic acid phosphatase type 2/haloperoxidase superfamily VAPA_1c50450 521649f8591d1dd40fae543ac3f1d64c 235 Pfam PF14378 PAP2 superfamily 72 212 1.5E-13 T 12-10-2018 IPR026841 Inositolphosphotransferase Aur1/Ipt1 VAPA_1c50450 521649f8591d1dd40fae543ac3f1d64c 235 Gene3D G3DSA:1.20.144.10 123 232 4.6E-12 T 12-10-2018 VAPA_1c50450 521649f8591d1dd40fae543ac3f1d64c 235 SMART SM00014 99 219 0.0017 T 12-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase VAPA_1c39750 8bdc10fee7c1427b7dc191e8bc177aa5 283 Gene3D G3DSA:3.60.21.10 1 281 5.2E-68 T 12-10-2018 IPR029052 Metallo-dependent phosphatase-like VAPA_1c39750 8bdc10fee7c1427b7dc191e8bc177aa5 283 Pfam PF00149 Calcineurin-like phosphoesterase 3 79 3.4E-11 T 12-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 VAPA_1c39750 8bdc10fee7c1427b7dc191e8bc177aa5 283 TIGRFAM TIGR00668 apaH: bis(5'-nucleosyl)-tetraphosphatase (symmetrical) 1 258 5.5E-73 T 12-10-2018 IPR004617 Bis(5'-nucleosyl)-tetraphosphatase (symmetrical) GO:0008803 KEGG: 00230+3.6.1.41 VAPA_1c39750 8bdc10fee7c1427b7dc191e8bc177aa5 283 SUPERFAMILY SSF56300 1 272 1.35E-48 T 12-10-2018 VAPA_1c39750 8bdc10fee7c1427b7dc191e8bc177aa5 283 PIRSF PIRSF000903 1 279 1.3E-93 T 12-10-2018 IPR004617 Bis(5'-nucleosyl)-tetraphosphatase (symmetrical) GO:0008803 KEGG: 00230+3.6.1.41 VAPA_2c07320 5be0a519e680b17fdda91ccdce1752e7 131 SUPERFAMILY SSF51230 53 126 3.53E-11 T 12-10-2018 IPR011053 Single hybrid motif VAPA_2c07320 5be0a519e680b17fdda91ccdce1752e7 131 Gene3D G3DSA:2.40.50.100 52 128 2.9E-13 T 12-10-2018 VAPA_2c07320 5be0a519e680b17fdda91ccdce1752e7 131 Pfam PF00364 Biotin-requiring enzyme 56 126 3.0E-8 T 12-10-2018 IPR000089 Biotin/lipoyl attachment VAPA_2c04000 551a0127c1cd32c02d0d1bf9d9a9b838 147 PIRSF PIRSF002721 1 147 1.1E-39 T 12-10-2018 IPR016364 Surface antigen, Rickettsia type VAPA_2c04000 551a0127c1cd32c02d0d1bf9d9a9b838 147 Pfam PF05433 Glycine zipper 2TM domain 27 65 1.4E-8 T 12-10-2018 IPR008816 Glycine zipper 2TM domain GO:0019867 VAPA_1c13230 9638f8653f634f141ce840805e912d05 301 Pfam PF00892 EamA-like transporter family 158 299 1.7E-14 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 VAPA_1c13230 9638f8653f634f141ce840805e912d05 301 Pfam PF00892 EamA-like transporter family 12 143 4.9E-21 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 VAPA_1c13230 9638f8653f634f141ce840805e912d05 301 SUPERFAMILY SSF103481 207 300 2.22E-12 T 12-10-2018 VAPA_1c13230 9638f8653f634f141ce840805e912d05 301 SUPERFAMILY SSF103481 45 147 4.45E-14 T 12-10-2018 VAPA_2c06390 9e5c1e3637f77d2acadca553883de5a0 103 Gene3D G3DSA:3.30.2310.20 1 102 3.8E-5 T 12-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily VAPA_2c06390 9e5c1e3637f77d2acadca553883de5a0 103 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 5 100 2.8E-7 T 12-10-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family VAPA_1c25480 b0d70a524813fe7a74a02a890c3b34f0 210 SUPERFAMILY SSF52402 16 192 3.89E-40 T 12-10-2018 VAPA_1c25480 b0d70a524813fe7a74a02a890c3b34f0 210 Gene3D G3DSA:3.40.50.620 3 210 1.6E-36 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold VAPA_1c25480 b0d70a524813fe7a74a02a890c3b34f0 210 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 44 189 2.8E-25 T 12-10-2018 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824 Reactome: R-HSA-196843 VAPA_1c10970 0d7dc4ac2b5a1b9352c618008133da72 321 Gene3D G3DSA:3.40.50.2300 135 276 2.3E-103 T 12-10-2018 VAPA_1c10970 0d7dc4ac2b5a1b9352c618008133da72 321 Pfam PF13407 Periplasmic binding protein domain 35 294 4.5E-48 T 12-10-2018 IPR025997 Periplasmic binding protein VAPA_1c10970 0d7dc4ac2b5a1b9352c618008133da72 321 SUPERFAMILY SSF53822 29 303 2.02E-72 T 12-10-2018 IPR028082 Periplasmic binding protein-like I VAPA_1c10970 0d7dc4ac2b5a1b9352c618008133da72 321 Gene3D G3DSA:3.40.50.2300 34 293 2.3E-103 T 12-10-2018 VAPA_2c09900 87df46404bff1a60e5f64b4c5850e320 239 Gene3D G3DSA:2.60.120.10 27 130 6.4E-68 T 12-10-2018 IPR014710 RmlC-like jelly roll fold VAPA_2c09900 87df46404bff1a60e5f64b4c5850e320 239 Pfam PF05899 Protein of unknown function (DUF861) 166 232 7.9E-7 T 12-10-2018 IPR008579 Domain of unknown function DUF861, cupin-3 KEGG: 00230+3.5.3.26|MetaCyc: PWY-5692|MetaCyc: PWY-5698 VAPA_2c09900 87df46404bff1a60e5f64b4c5850e320 239 Gene3D G3DSA:2.60.120.10 131 233 6.4E-68 T 12-10-2018 IPR014710 RmlC-like jelly roll fold VAPA_2c09900 87df46404bff1a60e5f64b4c5850e320 239 SUPERFAMILY SSF51182 20 112 2.0E-5 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily VAPA_2c09900 87df46404bff1a60e5f64b4c5850e320 239 SUPERFAMILY SSF51182 136 235 5.13E-13 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily VAPA_1c40990 47bae710bb85bff7b6532fada5a7895c 204 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 37 184 2.1E-29 T 12-10-2018 IPR007387 TRAP transporter, small membrane protein DctQ VAPA_1c18510 ea869a9b46b9da84e0b4c97d8d0cdd95 313 TIGRFAM TIGR00765 yihY_not_rbn: YihY family inner membrane protein 20 281 2.9E-26 T 12-10-2018 IPR017039 Virulence factor BrkB VAPA_1c18510 ea869a9b46b9da84e0b4c97d8d0cdd95 313 Pfam PF03631 Virulence factor BrkB 31 285 7.7E-40 T 12-10-2018 IPR017039 Virulence factor BrkB VAPA_1c18510 ea869a9b46b9da84e0b4c97d8d0cdd95 313 PIRSF PIRSF035875 7 299 9.4E-36 T 12-10-2018 IPR017039 Virulence factor BrkB VAPA_1c36380 cc2a5e6619f1fc7fa12d2d9c45bfd300 150 TIGRFAM TIGR02378 nirD_assim_sml: nitrite reductase [NAD(P)H], small subunit 13 111 2.1E-25 T 12-10-2018 IPR012748 Nitrite reductase [NAD(P)H] small subunit, NirD GO:0008942|GO:0042128|GO:0055114 VAPA_1c36380 cc2a5e6619f1fc7fa12d2d9c45bfd300 150 Pfam PF00355 Rieske [2Fe-2S] domain 13 97 6.6E-14 T 12-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 VAPA_1c36380 cc2a5e6619f1fc7fa12d2d9c45bfd300 150 SUPERFAMILY SSF50022 11 112 1.7E-32 T 12-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 VAPA_1c36380 cc2a5e6619f1fc7fa12d2d9c45bfd300 150 Gene3D G3DSA:2.102.10.10 9 120 9.9E-26 T 12-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 VAPA_1c33110 7344d1b1c69ab8dcb0fd48e0be83bb35 151 Gene3D G3DSA:3.50.30.10 11 149 5.8E-44 T 12-10-2018 VAPA_1c33110 7344d1b1c69ab8dcb0fd48e0be83bb35 151 SUPERFAMILY SSF52016 12 142 2.51E-38 T 12-10-2018 VAPA_1c33110 7344d1b1c69ab8dcb0fd48e0be83bb35 151 PIRSF PIRSF004966 10 144 3.3E-36 T 12-10-2018 IPR012016 Aconitase X subunit 2, putative VAPA_1c33110 7344d1b1c69ab8dcb0fd48e0be83bb35 151 Pfam PF01989 Protein of unknown function DUF126 34 111 5.2E-25 T 12-10-2018 IPR002840 Aconitase X swivel domain, putative VAPA_2c03770 8555f1ba4507769510691000b2598173 271 SUPERFAMILY SSF161098 71 255 8.5E-31 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_2c03770 8555f1ba4507769510691000b2598173 271 Gene3D G3DSA:1.10.3720.10 65 265 2.4E-23 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_2c03770 8555f1ba4507769510691000b2598173 271 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 94 263 1.4E-21 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 VAPA_2c05430 34f61fb98e11efd76246e03e9048f811 204 ProDom PD037531 MEMBRANE HYDROGENASE SUBUNIT COMPONENT HYDROGENASE-4 E OXIDOREDUCTASE PRECURSOR SIGNAL 1.-.-.- 5 185 1.0E-38 T 12-10-2018 VAPA_1c51970 d7755c741e7688c1d7774c6bad5c1a4f 309 Pfam PF02653 Branched-chain amino acid transport system / permease component 8 295 2.5E-31 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 VAPA_1c34600 44eea37deaa47161f4358a1c09d951a3 49 TIGRFAM TIGR02106 cyd_oper_ybgT: cyd operon protein YbgT 1 30 5.5E-20 T 12-10-2018 IPR011724 Cyd operon protein YbgT MetaCyc: PWY-7545 VAPA_1c34600 44eea37deaa47161f4358a1c09d951a3 49 Pfam PF08173 Membrane bound YbgT-like protein 1 26 2.6E-14 T 12-10-2018 IPR012994 Membrane bound YbgT-like VAPA_1c53660 cfedddec75baf306a7786312b6b46fc2 117 Pfam PF04020 Mycobacterial 4 TMS phage holin, superfamily IV 1 104 8.8E-32 T 12-10-2018 IPR007165 Mycobacterial 4 TMS phage holin, superfamily IV VAPA_2c07790 ab2deea53002b1f453fe371b951d8843 325 Gene3D G3DSA:3.40.190.150 27 312 8.6E-93 T 12-10-2018 VAPA_2c07790 ab2deea53002b1f453fe371b951d8843 325 SUPERFAMILY SSF53850 110 286 3.98E-5 T 12-10-2018 VAPA_2c07790 ab2deea53002b1f453fe371b951d8843 325 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 46 304 6.1E-67 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_2c07790 ab2deea53002b1f453fe371b951d8843 325 PIRSF PIRSF017082 1 325 7.3E-60 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_2c07790 ab2deea53002b1f453fe371b951d8843 325 Gene3D G3DSA:3.40.190.10 125 250 8.6E-93 T 12-10-2018 VAPA_1c33990 2f859ee4059df20ec536849eb504b727 1218 Pfam PF05378 Hydantoinase/oxoprolinase N-terminal region 13 192 7.0E-60 T 12-10-2018 IPR008040 Hydantoinaseoxoprolinase, N-terminal Reactome: R-HSA-174403|Reactome: R-HSA-5578998 VAPA_1c33990 2f859ee4059df20ec536849eb504b727 1218 Pfam PF02538 Hydantoinase B/oxoprolinase 709 1215 7.2E-202 T 12-10-2018 IPR003692 Hydantoinase B/oxoprolinase GO:0003824 Reactome: R-HSA-174403|Reactome: R-HSA-5578998 VAPA_1c33990 2f859ee4059df20ec536849eb504b727 1218 Pfam PF01968 Hydantoinase/oxoprolinase 211 498 3.7E-110 T 12-10-2018 IPR002821 Hydantoinase A/oxoprolinase GO:0016787 Reactome: R-HSA-174403|Reactome: R-HSA-5578998 VAPA_1c35930 a2dd74215adc23fde905706abea27997 398 Pfam PF13458 Periplasmic binding protein 28 362 5.1E-82 T 12-10-2018 IPR028081 Leucine-binding protein domain VAPA_1c35930 a2dd74215adc23fde905706abea27997 398 Gene3D G3DSA:3.40.50.2300 147 278 2.7E-107 T 12-10-2018 VAPA_1c35930 a2dd74215adc23fde905706abea27997 398 Gene3D G3DSA:3.40.50.2300 29 329 2.7E-107 T 12-10-2018 VAPA_1c35930 a2dd74215adc23fde905706abea27997 398 SUPERFAMILY SSF53822 28 397 2.86E-87 T 12-10-2018 IPR028082 Periplasmic binding protein-like I VAPA_1c49200 23c52c50279653b4fdfeffe682f55998 242 Pfam PF00583 Acetyltransferase (GNAT) family 96 166 6.5E-6 T 12-10-2018 IPR000182 GNAT domain VAPA_1c49200 23c52c50279653b4fdfeffe682f55998 242 Gene3D G3DSA:3.40.630.30 36 213 2.3E-23 T 12-10-2018 VAPA_1c49200 23c52c50279653b4fdfeffe682f55998 242 SUPERFAMILY SSF55729 40 177 8.15E-16 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase VAPA_1c53670 be7c52c874991584139d479609da170d 521 Pfam PF01435 Peptidase family M48 110 278 5.8E-30 T 12-10-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 VAPA_1c41690 31adbe864b8fd062977ed350645cb7bc 325 SUPERFAMILY SSF103481 80 173 2.09E-9 T 12-10-2018 VAPA_1c41690 31adbe864b8fd062977ed350645cb7bc 325 Pfam PF00892 EamA-like transporter family 37 169 6.9E-7 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 VAPA_1c41690 31adbe864b8fd062977ed350645cb7bc 325 Pfam PF00892 EamA-like transporter family 178 302 6.1E-7 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 VAPA_1c41690 31adbe864b8fd062977ed350645cb7bc 325 SUPERFAMILY SSF103481 215 306 4.84E-12 T 12-10-2018 VAPA_2c05750 e1232d31405b6cdd8ad6556c6550b735 320 Pfam PF12833 Helix-turn-helix domain 222 296 1.1E-18 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 VAPA_2c05750 e1232d31405b6cdd8ad6556c6550b735 320 SMART SM00342 216 299 1.7E-20 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 VAPA_2c05750 e1232d31405b6cdd8ad6556c6550b735 320 SUPERFAMILY SSF46689 200 249 7.88E-11 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 VAPA_2c05750 e1232d31405b6cdd8ad6556c6550b735 320 Gene3D G3DSA:1.10.10.60 200 303 1.3E-24 T 12-10-2018 VAPA_2c05750 e1232d31405b6cdd8ad6556c6550b735 320 Pfam PF06719 AraC-type transcriptional regulator N-terminus 36 187 3.7E-43 T 12-10-2018 IPR009594 Transcription regulator HTH, AraC, N-terminal VAPA_2c05750 e1232d31405b6cdd8ad6556c6550b735 320 SUPERFAMILY SSF46689 252 300 6.72E-8 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 VAPA_1c47540 42daedb3d1cc208e935a3c7a8001ba71 427 Gene3D G3DSA:2.30.40.10 9 425 2.3E-109 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 VAPA_1c47540 42daedb3d1cc208e935a3c7a8001ba71 427 SUPERFAMILY SSF51556 56 365 2.8E-79 T 12-10-2018 IPR032466 Metal-dependent hydrolase VAPA_1c47540 42daedb3d1cc208e935a3c7a8001ba71 427 TIGRFAM TIGR00857 pyrC_multi: dihydroorotase, multifunctional complex type 20 425 1.7E-89 T 12-10-2018 VAPA_1c47540 42daedb3d1cc208e935a3c7a8001ba71 427 SUPERFAMILY SSF51338 1 426 6.7E-29 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 VAPA_1c47540 42daedb3d1cc208e935a3c7a8001ba71 427 Gene3D G3DSA:3.20.20.140 57 368 2.3E-109 T 12-10-2018 VAPA_1c47540 42daedb3d1cc208e935a3c7a8001ba71 427 Pfam PF07969 Amidohydrolase family 222 426 5.2E-8 T 12-10-2018 IPR013108 Amidohydrolase 3 VAPA_1c24430 7b97d73470abdb860ce63a263877e01c 234 Pfam PF00043 Glutathione S-transferase, C-terminal domain 114 200 4.4E-15 T 12-10-2018 IPR004046 Glutathione S-transferase, C-terminal VAPA_1c24430 7b97d73470abdb860ce63a263877e01c 234 Pfam PF02798 Glutathione S-transferase, N-terminal domain 5 83 2.3E-13 T 12-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 VAPA_1c24430 7b97d73470abdb860ce63a263877e01c 234 Gene3D G3DSA:3.40.30.10 6 208 1.3E-87 T 12-10-2018 VAPA_1c24430 7b97d73470abdb860ce63a263877e01c 234 SUPERFAMILY SSF47616 81 207 1.77E-39 T 12-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily VAPA_1c24430 7b97d73470abdb860ce63a263877e01c 234 SUPERFAMILY SSF52833 3 87 1.83E-20 T 12-10-2018 IPR036249 Thioredoxin-like superfamily VAPA_1c24430 7b97d73470abdb860ce63a263877e01c 234 Gene3D G3DSA:1.20.1050.10 91 199 1.3E-87 T 12-10-2018 VAPA_1c20990 1e0e47d7fa200bd54bc9a2956a0b85e0 248 SMART SM00052 2 244 8.6E-20 T 12-10-2018 IPR001633 EAL domain VAPA_1c20990 1e0e47d7fa200bd54bc9a2956a0b85e0 248 Gene3D G3DSA:3.20.20.450 10 248 2.0E-58 T 12-10-2018 IPR035919 EAL domain superfamily VAPA_1c20990 1e0e47d7fa200bd54bc9a2956a0b85e0 248 SUPERFAMILY SSF141868 15 235 3.01E-54 T 12-10-2018 IPR035919 EAL domain superfamily VAPA_1c20990 1e0e47d7fa200bd54bc9a2956a0b85e0 248 Pfam PF00563 EAL domain 16 235 4.0E-46 T 12-10-2018 IPR001633 EAL domain VAPA_1c19490 5f9964cb0ccb2b6c74cb989878c9d1dd 292 Pfam PF01261 Xylose isomerase-like TIM barrel 33 244 4.8E-26 T 12-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain VAPA_1c19490 5f9964cb0ccb2b6c74cb989878c9d1dd 292 Gene3D G3DSA:3.20.20.150 6 291 1.5E-61 T 12-10-2018 VAPA_1c19490 5f9964cb0ccb2b6c74cb989878c9d1dd 292 SUPERFAMILY SSF51658 11 277 1.57E-45 T 12-10-2018 IPR036237 Xylose isomerase-like superfamily VAPA_1c07750 b653dba8432bbb58d1ca5052f9e73bfd 390 Gene3D G3DSA:2.40.230.10 122 390 1.3E-74 T 12-10-2018 IPR036541 Phospholipase A1 superfamily GO:0004620|GO:0006629|GO:0016020 KEGG: 00564+3.1.1.32+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.32+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417|MetaCyc: PWY-7783 VAPA_1c07750 b653dba8432bbb58d1ca5052f9e73bfd 390 Pfam PF02253 Phospholipase A1 117 387 1.3E-87 T 12-10-2018 IPR003187 Phospholipase A1 GO:0004620|GO:0006629|GO:0016020 KEGG: 00564+3.1.1.32+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.32+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417|MetaCyc: PWY-7783 VAPA_1c07750 b653dba8432bbb58d1ca5052f9e73bfd 390 PRINTS PR01486 Bacterial phospholipase A1 protein signature 194 210 2.8E-20 T 12-10-2018 IPR003187 Phospholipase A1 GO:0004620|GO:0006629|GO:0016020 KEGG: 00564+3.1.1.32+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.32+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417|MetaCyc: PWY-7783 VAPA_1c07750 b653dba8432bbb58d1ca5052f9e73bfd 390 PRINTS PR01486 Bacterial phospholipase A1 protein signature 299 317 2.8E-20 T 12-10-2018 IPR003187 Phospholipase A1 GO:0004620|GO:0006629|GO:0016020 KEGG: 00564+3.1.1.32+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.32+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417|MetaCyc: PWY-7783 VAPA_1c07750 b653dba8432bbb58d1ca5052f9e73bfd 390 PRINTS PR01486 Bacterial phospholipase A1 protein signature 263 281 2.8E-20 T 12-10-2018 IPR003187 Phospholipase A1 GO:0004620|GO:0006629|GO:0016020 KEGG: 00564+3.1.1.32+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.32+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417|MetaCyc: PWY-7783 VAPA_1c07750 b653dba8432bbb58d1ca5052f9e73bfd 390 PRINTS PR01486 Bacterial phospholipase A1 protein signature 217 236 2.8E-20 T 12-10-2018 IPR003187 Phospholipase A1 GO:0004620|GO:0006629|GO:0016020 KEGG: 00564+3.1.1.32+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.32+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417|MetaCyc: PWY-7783 VAPA_1c07750 b653dba8432bbb58d1ca5052f9e73bfd 390 PRINTS PR01486 Bacterial phospholipase A1 protein signature 360 380 2.8E-20 T 12-10-2018 IPR003187 Phospholipase A1 GO:0004620|GO:0006629|GO:0016020 KEGG: 00564+3.1.1.32+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.32+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417|MetaCyc: PWY-7783 VAPA_1c07750 b653dba8432bbb58d1ca5052f9e73bfd 390 SUPERFAMILY SSF56931 119 389 2.62E-73 T 12-10-2018 IPR036541 Phospholipase A1 superfamily GO:0004620|GO:0006629|GO:0016020 KEGG: 00564+3.1.1.32+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.32+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417|MetaCyc: PWY-7783 VAPA_1c41430 31699ec25a63d3054162d6e3c062a1ec 521 Pfam PF00144 Beta-lactamase 218 499 1.7E-21 T 12-10-2018 IPR001466 Beta-lactamase-related VAPA_1c41430 31699ec25a63d3054162d6e3c062a1ec 521 Gene3D G3DSA:3.40.710.10 194 510 3.8E-55 T 12-10-2018 VAPA_1c41430 31699ec25a63d3054162d6e3c062a1ec 521 SUPERFAMILY SSF56601 177 499 9.86E-62 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like VAPA_1c08850 23382ce5656c89d2da7b81b087386391 480 SUPERFAMILY SSF75304 5 476 9.55E-119 T 12-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 VAPA_1c08850 23382ce5656c89d2da7b81b087386391 480 Pfam PF01425 Amidase 27 458 3.6E-83 T 12-10-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 VAPA_1c08850 23382ce5656c89d2da7b81b087386391 480 Gene3D G3DSA:3.90.1300.10 2 478 1.3E-128 T 12-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 VAPA_1c05390 c6965a8d72bb3513ef5b6dfadbf88c9f 680 SUPERFAMILY SSF53335 482 617 1.43E-18 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase VAPA_1c05390 c6965a8d72bb3513ef5b6dfadbf88c9f 680 Gene3D G3DSA:3.40.50.150 426 671 1.4E-31 T 12-10-2018 VAPA_1c05390 c6965a8d72bb3513ef5b6dfadbf88c9f 680 SUPERFAMILY SSF103473 13 388 1.4E-6 T 12-10-2018 IPR036259 MFS transporter superfamily VAPA_1c37080 652267b11463d48354568f14ca9a4c77 279 Gene3D G3DSA:3.60.20.10 2 245 2.1E-25 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal VAPA_1c37080 652267b11463d48354568f14ca9a4c77 279 PIRSF PIRSF009120 1 259 2.6E-114 T 12-10-2018 IPR016545 Uncharacterised conserved protein UCP009120, proteasome-type protease, Sll0069 VAPA_1c37080 652267b11463d48354568f14ca9a4c77 279 SUPERFAMILY SSF56235 2 250 1.25E-34 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal VAPA_1c43050 c63414d1cb0b0ba2850bdc66668dd574 179 Pfam PF06042 Nucleotidyltransferase 14 176 2.5E-52 T 12-10-2018 IPR009267 Putative nucleotidyltransferase VAPA_1c30110 9ff432882fd211f4e5be9667b8ee6f7f 348 ProSitePatterns PS00920 Nitrilases / cyanide hydratase signature 1. 41 56 - T 12-10-2018 IPR000132 Nitrilase/cyanide hydratase, conserved site GO:0016810 VAPA_1c30110 9ff432882fd211f4e5be9667b8ee6f7f 348 Pfam PF00795 Carbon-nitrogen hydrolase 10 286 6.6E-56 T 12-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 VAPA_1c30110 9ff432882fd211f4e5be9667b8ee6f7f 348 SUPERFAMILY SSF56317 8 309 7.59E-76 T 12-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily VAPA_1c30110 9ff432882fd211f4e5be9667b8ee6f7f 348 Gene3D G3DSA:3.60.110.10 3 294 3.0E-103 T 12-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily VAPA_1c53160 419575cc78a8fc5cd26ac8fe4fdffd9c 541 Pfam PF05977 Transmembrane secretion effector 22 540 2.3E-142 T 12-10-2018 IPR010290 Transmembrane secretion effector VAPA_1c53160 419575cc78a8fc5cd26ac8fe4fdffd9c 541 SUPERFAMILY SSF103473 30 415 4.58E-50 T 12-10-2018 IPR036259 MFS transporter superfamily VAPA_1c53160 419575cc78a8fc5cd26ac8fe4fdffd9c 541 Gene3D G3DSA:1.20.1250.20 30 415 3.3E-38 T 12-10-2018 VAPA_1c36200 d62f4a5e3e1d32dd3b6c6e9025cd86e5 137 TIGRFAM TIGR00810 secG: preprotein translocase, SecG subunit 6 76 2.9E-25 T 12-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 VAPA_1c36200 d62f4a5e3e1d32dd3b6c6e9025cd86e5 137 Pfam PF03840 Preprotein translocase SecG subunit 8 76 1.4E-21 T 12-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 VAPA_1c36200 d62f4a5e3e1d32dd3b6c6e9025cd86e5 137 PRINTS PR01651 Protein-export SecG membrane protein signature 6 26 1.4E-32 T 12-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 VAPA_1c36200 d62f4a5e3e1d32dd3b6c6e9025cd86e5 137 PRINTS PR01651 Protein-export SecG membrane protein signature 26 40 1.4E-32 T 12-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 VAPA_1c36200 d62f4a5e3e1d32dd3b6c6e9025cd86e5 137 PRINTS PR01651 Protein-export SecG membrane protein signature 41 57 1.4E-32 T 12-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 VAPA_1c36200 d62f4a5e3e1d32dd3b6c6e9025cd86e5 137 PRINTS PR01651 Protein-export SecG membrane protein signature 57 79 1.4E-32 T 12-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 VAPA_1c31440 7ba741f28784c3fcfc97ef1bee896a2c 313 Pfam PF01874 ATP:dephospho-CoA triphosphoribosyl transferase 14 292 9.1E-60 T 12-10-2018 IPR002736 Triphosphoribosyl-dephospho-CoA protein GO:0005524|GO:0016310|GO:0046917 MetaCyc: PWY-5796 VAPA_1c31440 7ba741f28784c3fcfc97ef1bee896a2c 313 Gene3D G3DSA:1.10.4200.10 36 296 6.5E-51 T 12-10-2018 VAPA_1c16240 bc6de703e0971ae5ac7a7d12b83238fc 330 Pfam PF00482 Type II secretion system (T2SS), protein F 163 287 2.3E-18 T 12-10-2018 IPR018076 Type II secretion system F domain VAPA_1c16240 bc6de703e0971ae5ac7a7d12b83238fc 330 Gene3D G3DSA:1.20.81.30 155 264 8.7E-8 T 12-10-2018 VAPA_1c34570 d9bc0632f6218f5009c7a564e956df2a 285 Gene3D G3DSA:3.90.850.10 67 284 1.4E-79 T 12-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 VAPA_1c34570 d9bc0632f6218f5009c7a564e956df2a 285 SUPERFAMILY SSF56529 62 280 7.06E-76 T 12-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 VAPA_1c34570 d9bc0632f6218f5009c7a564e956df2a 285 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 73 278 9.1E-65 T 12-10-2018 IPR011234 Fumarylacetoacetase-like, C-terminal GO:0003824 VAPA_1c28050 8dfb0b93ccc24ff7ac9d71466a522726 131 Pfam PF03640 Secreted repeat of unknown function 86 129 7.0E-19 T 12-10-2018 IPR005297 Lipoprotein repeat VAPA_1c28050 8dfb0b93ccc24ff7ac9d71466a522726 131 Pfam PF03640 Secreted repeat of unknown function 34 73 9.4E-14 T 12-10-2018 IPR005297 Lipoprotein repeat VAPA_1c28050 8dfb0b93ccc24ff7ac9d71466a522726 131 PIRSF PIRSF029720 1 131 4.1E-43 T 12-10-2018 IPR014558 Uncharacterised conserved lipoprotein VAPA_1c14120 46972ed30aca67eb82cff72c3bb5127f 451 Pfam PF13379 NMT1-like family 93 330 1.1E-79 T 12-10-2018 VAPA_1c14120 46972ed30aca67eb82cff72c3bb5127f 451 Gene3D G3DSA:3.40.190.10 184 438 3.6E-113 T 12-10-2018 VAPA_1c14120 46972ed30aca67eb82cff72c3bb5127f 451 Gene3D G3DSA:3.40.190.10 98 433 3.6E-113 T 12-10-2018 VAPA_1c14120 46972ed30aca67eb82cff72c3bb5127f 451 SUPERFAMILY SSF53850 94 314 3.31E-37 T 12-10-2018 VAPA_1c53740 b99eaa2a0407b9d1c93143365fa2480a 386 Pfam PF16074 Type IV Pilus-assembly protein W 247 381 4.4E-16 T 12-10-2018 IPR032092 Type IV Pilus-assembly protein W GO:0043683 VAPA_1c53740 b99eaa2a0407b9d1c93143365fa2480a 386 Pfam PF07963 Prokaryotic N-terminal methylation motif 19 43 8.0E-7 T 12-10-2018 IPR012902 Prokaryotic N-terminal methylation site VAPA_1c53740 b99eaa2a0407b9d1c93143365fa2480a 386 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 21 42 1.9E-4 T 12-10-2018 IPR012902 Prokaryotic N-terminal methylation site VAPA_1c53740 b99eaa2a0407b9d1c93143365fa2480a 386 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 22 42 - T 12-10-2018 IPR012902 Prokaryotic N-terminal methylation site VAPA_1c14970 e51684b374eb6f96c68fd7c083cf4a9f 257 Pfam PF11967 Recombination protein O N terminal 9 81 4.9E-20 T 12-10-2018 IPR022572 DNA replication/recombination mediator RecO, N-terminal VAPA_1c14970 e51684b374eb6f96c68fd7c083cf4a9f 257 SUPERFAMILY SSF57863 91 160 9.15E-5 T 12-10-2018 IPR037278 ARFGAP/RecO-like zinc finger VAPA_1c14970 e51684b374eb6f96c68fd7c083cf4a9f 257 Gene3D G3DSA:2.40.50.140 8 81 4.9E-28 T 12-10-2018 VAPA_1c14970 e51684b374eb6f96c68fd7c083cf4a9f 257 Hamap MF_00201 DNA repair protein RecO [recO]. 6 254 20.976 T 12-10-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 VAPA_1c14970 e51684b374eb6f96c68fd7c083cf4a9f 257 Pfam PF02565 Recombination protein O C terminal 87 175 3.4E-11 T 12-10-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 VAPA_1c14970 e51684b374eb6f96c68fd7c083cf4a9f 257 SUPERFAMILY SSF50249 9 81 1.68E-12 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold VAPA_1c14970 e51684b374eb6f96c68fd7c083cf4a9f 257 Gene3D G3DSA:1.20.1440.120 86 257 9.2E-29 T 12-10-2018 VAPA_1c14970 e51684b374eb6f96c68fd7c083cf4a9f 257 TIGRFAM TIGR00613 reco: DNA repair protein RecO 14 160 1.6E-15 T 12-10-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 VAPA_1c17730 e1810c97bf08d390e817c3c443034ee1 405 PIRSF PIRSF020818 1 405 5.0E-168 T 12-10-2018 IPR010915 Polyhydroxyalkanoate depolymerase VAPA_1c17730 e1810c97bf08d390e817c3c443034ee1 405 Pfam PF06850 PHB de-polymerase C-terminus 200 400 4.9E-89 T 12-10-2018 IPR009656 PHB de-polymerase, C-terminal VAPA_1c17730 e1810c97bf08d390e817c3c443034ee1 405 TIGRFAM TIGR01849 PHB_depoly_PhaZ: polyhydroxyalkanoate depolymerase, intracellular 4 399 8.2E-157 T 12-10-2018 IPR010915 Polyhydroxyalkanoate depolymerase VAPA_1c17730 e1810c97bf08d390e817c3c443034ee1 405 SUPERFAMILY SSF53474 75 398 7.68E-33 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c17730 e1810c97bf08d390e817c3c443034ee1 405 Gene3D G3DSA:3.40.50.1820 67 390 4.2E-9 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c06150 313fa826c6714e2b9d8d44cd8dde0bac 374 Pfam PF09937 Uncharacterized protein conserved in bacteria (DUF2169) 21 323 6.9E-91 T 12-10-2018 IPR018683 Domain of unknown function DUF2169 VAPA_1c25440 a9cecd93ebb9ec9f67ae1dc287571463 346 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 12 294 2.4E-19 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 VAPA_1c25440 a9cecd93ebb9ec9f67ae1dc287571463 346 Gene3D G3DSA:3.50.50.60 12 310 2.3E-81 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c25440 a9cecd93ebb9ec9f67ae1dc287571463 346 Hamap MF_01685 Ferredoxin--NADP reductase. 10 331 36.232 T 12-10-2018 IPR022890 Ferredoxin--NADP reductase, type 2 GO:0004324|GO:0055114 KEGG: 00195+1.18.1.2|MetaCyc: PWY-101 VAPA_1c25440 a9cecd93ebb9ec9f67ae1dc287571463 346 Gene3D G3DSA:3.50.50.60 132 248 2.3E-81 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c25440 a9cecd93ebb9ec9f67ae1dc287571463 346 SUPERFAMILY SSF51905 12 313 1.01E-30 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c25440 a9cecd93ebb9ec9f67ae1dc287571463 346 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 268 290 2.6E-10 T 12-10-2018 VAPA_1c25440 a9cecd93ebb9ec9f67ae1dc287571463 346 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 13 32 2.6E-10 T 12-10-2018 VAPA_1c25440 a9cecd93ebb9ec9f67ae1dc287571463 346 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 160 178 2.6E-10 T 12-10-2018 VAPA_1c25440 a9cecd93ebb9ec9f67ae1dc287571463 346 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 241 257 2.6E-10 T 12-10-2018 VAPA_1c25440 a9cecd93ebb9ec9f67ae1dc287571463 346 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 117 125 1.2E-15 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 VAPA_1c25440 a9cecd93ebb9ec9f67ae1dc287571463 346 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 278 296 1.2E-15 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 VAPA_1c25440 a9cecd93ebb9ec9f67ae1dc287571463 346 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 69 79 1.2E-15 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 VAPA_1c25440 a9cecd93ebb9ec9f67ae1dc287571463 346 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 156 180 1.2E-15 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 VAPA_1c25440 a9cecd93ebb9ec9f67ae1dc287571463 346 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 12 34 1.2E-15 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 VAPA_1c43930 ac92e6d41dbf3d92e3a472b1775dd38c 405 SUPERFAMILY SSF53686 42 400 1.11E-47 T 12-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme VAPA_1c43930 ac92e6d41dbf3d92e3a472b1775dd38c 405 Gene3D G3DSA:3.40.50.1100 129 230 6.4E-75 T 12-10-2018 VAPA_1c43930 ac92e6d41dbf3d92e3a472b1775dd38c 405 Gene3D G3DSA:3.40.50.1100 91 398 6.4E-75 T 12-10-2018 VAPA_1c43930 ac92e6d41dbf3d92e3a472b1775dd38c 405 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 93 391 2.8E-47 T 12-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme VAPA_1c02590 3df30c87709beed2e662388cf65380ca 464 SUPERFAMILY SSF48371 128 428 1.13E-7 T 12-10-2018 IPR016024 Armadillo-type fold VAPA_1c02590 3df30c87709beed2e662388cf65380ca 464 Gene3D G3DSA:1.25.10.10 83 267 7.9E-6 T 12-10-2018 IPR011989 Armadillo-like helical VAPA_1c53180 91d76fab3dd8d91818934aed10186da1 233 Gene3D G3DSA:1.20.120.80 37 233 4.0E-53 T 12-10-2018 IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle GO:0004129|GO:0016020|GO:0022904 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 VAPA_1c53180 91d76fab3dd8d91818934aed10186da1 233 Pfam PF00510 Cytochrome c oxidase subunit III 42 233 1.7E-20 T 12-10-2018 IPR000298 Cytochrome c oxidase subunit III-like GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 VAPA_1c53180 91d76fab3dd8d91818934aed10186da1 233 SUPERFAMILY SSF81452 21 233 8.5E-51 T 12-10-2018 IPR035973 Cytochrome c oxidase subunit III-like superfamily GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 VAPA_1c17140 f5cc87e085c22809c33f96e91ea67127 195 Pfam PF09832 Uncharacterized protein conserved in bacteria (DUF2059) 106 146 1.9E-6 T 12-10-2018 IPR018637 Domain of unknown function DUF2059 VAPA_1c33070 b5f5036dd76738317b8634003f3f5c73 314 Gene3D G3DSA:3.20.20.100 39 310 8.7E-46 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily VAPA_1c33070 b5f5036dd76738317b8634003f3f5c73 314 SUPERFAMILY SSF51430 40 300 5.5E-53 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily VAPA_1c33070 b5f5036dd76738317b8634003f3f5c73 314 Pfam PF00248 Aldo/keto reductase family 55 296 1.8E-33 T 12-10-2018 IPR023210 NADP-dependent oxidoreductase domain VAPA_1c16950 6c1c0b6d21f537b804253213b54d705e 118 Pfam PF03334 Na+/H+ antiporter subunit 20 100 6.8E-20 T 12-10-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:1902600 VAPA_1c16950 6c1c0b6d21f537b804253213b54d705e 118 TIGRFAM TIGR01300 CPA3_mnhG_phaG: monovalent cation/proton antiporter, MnhG/PhaG subunit 20 106 5.2E-21 T 12-10-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:1902600 VAPA_1c44000 231b8d30f725a5010f6c7f0b682da869 198 PIRSF PIRSF016919 3 197 4.4E-52 T 12-10-2018 IPR007038 Hydrogenase/Urease accessory protein HupE/UreJ protein VAPA_1c44000 231b8d30f725a5010f6c7f0b682da869 198 Pfam PF04955 HupE / UreJ protein 11 193 1.0E-52 T 12-10-2018 IPR007038 Hydrogenase/Urease accessory protein HupE/UreJ protein VAPA_1c35560 42555067dfff522a946f28cacf45faa9 234 Gene3D G3DSA:3.40.50.300 10 171 2.8E-26 T 12-10-2018 VAPA_1c35560 42555067dfff522a946f28cacf45faa9 234 Pfam PF13521 AAA domain 11 167 1.1E-21 T 12-10-2018 IPR038727 NadR/Ttd14, AAA domain VAPA_1c35560 42555067dfff522a946f28cacf45faa9 234 SUPERFAMILY SSF52540 6 142 1.3E-9 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c04420 15a020a1fcfa208657091515ba653894 328 Pfam PF02653 Branched-chain amino acid transport system / permease component 34 295 7.6E-40 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 VAPA_1c04550 b17315e1ccbe6bec85ad35d9bf4654e4 296 Pfam PF00892 EamA-like transporter family 154 287 3.4E-14 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 VAPA_1c04550 b17315e1ccbe6bec85ad35d9bf4654e4 296 Pfam PF00892 EamA-like transporter family 10 140 2.0E-18 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 VAPA_1c04550 b17315e1ccbe6bec85ad35d9bf4654e4 296 SUPERFAMILY SSF103481 195 291 1.27E-9 T 12-10-2018 VAPA_1c04550 b17315e1ccbe6bec85ad35d9bf4654e4 296 SUPERFAMILY SSF103481 44 143 3.79E-14 T 12-10-2018 VAPA_1c16090 8475ad5b1285986932e6ef0a99547611 235 SUPERFAMILY SSF51735 9 234 3.28E-53 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c16090 8475ad5b1285986932e6ef0a99547611 235 Gene3D G3DSA:3.40.50.720 4 235 5.8E-54 T 12-10-2018 VAPA_1c16090 8475ad5b1285986932e6ef0a99547611 235 Pfam PF00106 short chain dehydrogenase 9 197 7.7E-47 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c16090 8475ad5b1285986932e6ef0a99547611 235 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 6.2E-20 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c16090 8475ad5b1285986932e6ef0a99547611 235 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 6.2E-20 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c16090 8475ad5b1285986932e6ef0a99547611 235 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 6.2E-20 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c16090 8475ad5b1285986932e6ef0a99547611 235 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 6.2E-20 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c16090 8475ad5b1285986932e6ef0a99547611 235 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 6.2E-20 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c50280 586e9e5bb958a80b23a02dd055a12d77 199 Gene3D G3DSA:1.20.1440.20 15 194 2.1E-59 T 12-10-2018 IPR023353 LemA-like domain superfamily VAPA_1c50280 586e9e5bb958a80b23a02dd055a12d77 199 Pfam PF04011 LemA family 8 194 6.9E-64 T 12-10-2018 IPR007156 LemA VAPA_1c50280 586e9e5bb958a80b23a02dd055a12d77 199 SUPERFAMILY SSF140478 24 181 1.57E-52 T 12-10-2018 IPR023353 LemA-like domain superfamily VAPA_2c04650 3f7f43448fc2d62299421f6f16310f2f 400 Gene3D G3DSA:2.40.30.170 45 322 4.3E-43 T 12-10-2018 VAPA_2c04650 3f7f43448fc2d62299421f6f16310f2f 400 Gene3D G3DSA:2.40.50.100 56 236 4.3E-43 T 12-10-2018 VAPA_2c04650 3f7f43448fc2d62299421f6f16310f2f 400 Pfam PF13437 HlyD family secretion protein 203 297 5.1E-5 T 12-10-2018 VAPA_2c04650 3f7f43448fc2d62299421f6f16310f2f 400 Gene3D G3DSA:1.10.287.470 90 192 4.3E-43 T 12-10-2018 VAPA_2c04650 3f7f43448fc2d62299421f6f16310f2f 400 Gene3D G3DSA:2.40.420.20 43 382 4.3E-43 T 12-10-2018 VAPA_2c04650 3f7f43448fc2d62299421f6f16310f2f 400 SUPERFAMILY SSF111369 50 170 7.32E-5 T 12-10-2018 VAPA_2c05830 c7bd5180623e6c88ac52fab120e17559 444 Gene3D G3DSA:1.10.3860.10 2 419 5.5E-107 T 12-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 VAPA_2c05830 c7bd5180623e6c88ac52fab120e17559 444 ProSitePatterns PS00714 Sodium:dicarboxylate symporter family signature 2. 296 319 - T 12-10-2018 IPR018107 Sodium:dicarboxylate symporter, conserved site VAPA_2c05830 c7bd5180623e6c88ac52fab120e17559 444 Pfam PF00375 Sodium:dicarboxylate symporter family 10 400 8.9E-98 T 12-10-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 VAPA_2c05830 c7bd5180623e6c88ac52fab120e17559 444 SUPERFAMILY SSF118215 10 403 1.18E-108 T 12-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 VAPA_2c05830 c7bd5180623e6c88ac52fab120e17559 444 PRINTS PR00173 Glutamate-aspartate symporter signature 75 100 7.8E-30 T 12-10-2018 VAPA_2c05830 c7bd5180623e6c88ac52fab120e17559 444 PRINTS PR00173 Glutamate-aspartate symporter signature 219 238 7.8E-30 T 12-10-2018 VAPA_2c05830 c7bd5180623e6c88ac52fab120e17559 444 PRINTS PR00173 Glutamate-aspartate symporter signature 4 24 7.8E-30 T 12-10-2018 VAPA_2c05830 c7bd5180623e6c88ac52fab120e17559 444 PRINTS PR00173 Glutamate-aspartate symporter signature 356 376 7.8E-30 T 12-10-2018 VAPA_2c05830 c7bd5180623e6c88ac52fab120e17559 444 PRINTS PR00173 Glutamate-aspartate symporter signature 45 65 7.8E-30 T 12-10-2018 VAPA_2c05830 c7bd5180623e6c88ac52fab120e17559 444 PRINTS PR00173 Glutamate-aspartate symporter signature 293 319 7.8E-30 T 12-10-2018 VAPA_2c06720 e3a8dc1c277342f9480de6c84a0e24a4 139 SUPERFAMILY SSF51182 24 122 3.96E-19 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily VAPA_2c06720 e3a8dc1c277342f9480de6c84a0e24a4 139 Pfam PF07883 Cupin domain 45 116 5.7E-13 T 12-10-2018 IPR013096 Cupin 2, conserved barrel VAPA_2c06720 e3a8dc1c277342f9480de6c84a0e24a4 139 Gene3D G3DSA:2.60.120.10 14 125 2.5E-17 T 12-10-2018 IPR014710 RmlC-like jelly roll fold VAPA_2c06720 e3a8dc1c277342f9480de6c84a0e24a4 139 PIRSF PIRSF037087 2 139 6.5E-40 T 12-10-2018 IPR017102 Uncharacterised conserved protein UCP037087 VAPA_1c11880 79a4dbc725668eecb83713724bb9cd5f 294 PIRSF PIRSF026649 2 294 7.9E-75 T 12-10-2018 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 VAPA_1c11880 79a4dbc725668eecb83713724bb9cd5f 294 Pfam PF03279 Bacterial lipid A biosynthesis acyltransferase 7 285 2.5E-60 T 12-10-2018 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 VAPA_1c17850 f170108c5302b3617dff08d65d4df226 137 Pfam PF04993 TfoX N-terminal domain 10 102 2.9E-28 T 12-10-2018 IPR007076 TfoX, N-terminal VAPA_1c17850 f170108c5302b3617dff08d65d4df226 137 Gene3D G3DSA:3.30.1460.30 2 103 3.1E-32 T 12-10-2018 VAPA_1c17850 f170108c5302b3617dff08d65d4df226 137 SUPERFAMILY SSF159894 4 103 2.56E-29 T 12-10-2018 VAPA_1c05380 1480d38a572f62e1d8e2e9545abbd1d8 150 Pfam PF09980 Predicted membrane protein (DUF2214) 4 149 7.5E-50 T 12-10-2018 IPR018706 Protein of unknown function DUF2214, membrane VAPA_2c00670 669fcefb5774ab15797362e2141d3a13 115 Pfam PF01042 Endoribonuclease L-PSP 4 115 2.8E-27 T 12-10-2018 IPR006175 YjgF/YER057c/UK114 family Reactome: R-HSA-8849175 VAPA_2c00670 669fcefb5774ab15797362e2141d3a13 115 ProSitePatterns PS01094 Uncharacterized protein family UPF0076 signature. 91 109 - T 12-10-2018 IPR019897 RidA, conserved site Reactome: R-HSA-8849175 VAPA_2c00670 669fcefb5774ab15797362e2141d3a13 115 Gene3D G3DSA:3.30.1330.40 1 115 6.2E-42 T 12-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 VAPA_2c00670 669fcefb5774ab15797362e2141d3a13 115 SUPERFAMILY SSF55298 8 115 4.4E-32 T 12-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 VAPA_1c30590 8f506e0d2f69b714989fe1fc60c92884 295 Gene3D G3DSA:3.40.50.1820 8 291 1.6E-63 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c30590 8f506e0d2f69b714989fe1fc60c92884 295 Pfam PF12697 Alpha/beta hydrolase family 35 283 2.5E-12 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 VAPA_1c30590 8f506e0d2f69b714989fe1fc60c92884 295 SUPERFAMILY SSF53474 10 283 1.12E-42 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c45290 1eb2e17a7a0d3c7ccaab143dfb7ec2cd 208 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 24 195 1.6E-31 T 12-10-2018 IPR003740 Uncharacterised membrane protein YitT VAPA_1c53440 f4c76ae641ae7c4f0e312cc417b68125 219 Pfam PF00691 OmpA family 112 206 3.9E-20 T 12-10-2018 IPR006665 OmpA-like domain VAPA_1c53440 f4c76ae641ae7c4f0e312cc417b68125 219 PRINTS PR01021 OMPA domain signature 142 157 3.2E-12 T 12-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 VAPA_1c53440 f4c76ae641ae7c4f0e312cc417b68125 219 PRINTS PR01021 OMPA domain signature 112 134 3.2E-12 T 12-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 VAPA_1c53440 f4c76ae641ae7c4f0e312cc417b68125 219 PRINTS PR01021 OMPA domain signature 157 173 3.2E-12 T 12-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 VAPA_1c53440 f4c76ae641ae7c4f0e312cc417b68125 219 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 157 174 2.5E-6 T 12-10-2018 VAPA_1c53440 f4c76ae641ae7c4f0e312cc417b68125 219 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 175 194 2.5E-6 T 12-10-2018 VAPA_1c53440 f4c76ae641ae7c4f0e312cc417b68125 219 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 195 215 2.5E-6 T 12-10-2018 VAPA_1c53440 f4c76ae641ae7c4f0e312cc417b68125 219 SUPERFAMILY SSF103088 100 212 1.31E-36 T 12-10-2018 IPR036737 OmpA-like domain superfamily VAPA_1c53440 f4c76ae641ae7c4f0e312cc417b68125 219 Gene3D G3DSA:3.30.1330.60 74 216 7.2E-43 T 12-10-2018 IPR036737 OmpA-like domain superfamily VAPA_1c53440 f4c76ae641ae7c4f0e312cc417b68125 219 Pfam PF13488 Glycine zipper 31 79 4.5E-10 T 12-10-2018 IPR039567 Glycine zipper domain VAPA_1c24870 6026dc4407107cd7830bc2c37aa57594 316 Pfam PF00487 Fatty acid desaturase 36 272 1.5E-19 T 12-10-2018 IPR005804 Fatty acid desaturase domain GO:0006629 VAPA_2c06290 1163479413387f9b77784bbdc7f26f73 268 Gene3D G3DSA:3.30.70.1530 30 101 1.3E-22 T 12-10-2018 VAPA_2c06290 1163479413387f9b77784bbdc7f26f73 268 Gene3D G3DSA:3.30.300.30 103 208 9.9E-33 T 12-10-2018 VAPA_2c06290 1163479413387f9b77784bbdc7f26f73 268 PRINTS PR01338 Type III secretion system outer membrane K protein family signature 175 187 2.3E-27 T 12-10-2018 IPR003282 Type III secretion system lipoprotein HrcJ/YscJ GO:0009306 VAPA_2c06290 1163479413387f9b77784bbdc7f26f73 268 PRINTS PR01338 Type III secretion system outer membrane K protein family signature 35 45 2.3E-27 T 12-10-2018 IPR003282 Type III secretion system lipoprotein HrcJ/YscJ GO:0009306 VAPA_2c06290 1163479413387f9b77784bbdc7f26f73 268 PRINTS PR01338 Type III secretion system outer membrane K protein family signature 107 122 2.3E-27 T 12-10-2018 IPR003282 Type III secretion system lipoprotein HrcJ/YscJ GO:0009306 VAPA_2c06290 1163479413387f9b77784bbdc7f26f73 268 PRINTS PR01338 Type III secretion system outer membrane K protein family signature 127 140 2.3E-27 T 12-10-2018 IPR003282 Type III secretion system lipoprotein HrcJ/YscJ GO:0009306 VAPA_2c06290 1163479413387f9b77784bbdc7f26f73 268 PRINTS PR01338 Type III secretion system outer membrane K protein family signature 87 100 2.3E-27 T 12-10-2018 IPR003282 Type III secretion system lipoprotein HrcJ/YscJ GO:0009306 VAPA_2c06290 1163479413387f9b77784bbdc7f26f73 268 TIGRFAM TIGR02544 III_secr_YscJ: type III secretion apparatus lipoprotein, YscJ/HrcJ family 16 202 6.0E-68 T 12-10-2018 IPR003282 Type III secretion system lipoprotein HrcJ/YscJ GO:0009306 VAPA_2c06290 1163479413387f9b77784bbdc7f26f73 268 Pfam PF01514 Secretory protein of YscJ/FliF family 22 194 1.6E-31 T 12-10-2018 IPR006182 Secretory protein YscJ/FliF VAPA_1c01290 0300fb4e4e620a6782e6f7a7c00d5fa5 145 SUPERFAMILY SSF54593 13 138 2.75E-26 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase VAPA_1c01290 0300fb4e4e620a6782e6f7a7c00d5fa5 145 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 14 138 1.3E-13 T 12-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain VAPA_1c01290 0300fb4e4e620a6782e6f7a7c00d5fa5 145 Gene3D G3DSA:3.10.180.10 12 141 2.1E-26 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase VAPA_1c37990 b9ac26fe3df3da8044fbacd997654c25 349 SUPERFAMILY SSF56266 14 332 2.09E-70 T 12-10-2018 IPR016117 ArgJ-like domain superfamily KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 VAPA_1c37990 b9ac26fe3df3da8044fbacd997654c25 349 Pfam PF03576 Peptidase family S58 17 333 8.0E-64 T 12-10-2018 IPR005321 Peptidase S58, DmpA VAPA_1c37990 b9ac26fe3df3da8044fbacd997654c25 349 Gene3D G3DSA:3.60.70.12 12 347 8.7E-112 T 12-10-2018 IPR016117 ArgJ-like domain superfamily KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 VAPA_1c26010 9e8052601cdcf4b874387ff45a6f5ec5 366 Gene3D G3DSA:3.30.1400.10 270 348 3.6E-6 T 12-10-2018 IPR036765 ZipA, C-terminal FtsZ-binding domain superfamily GO:0090529 VAPA_1c26010 9e8052601cdcf4b874387ff45a6f5ec5 366 SUPERFAMILY SSF64383 215 349 1.05E-16 T 12-10-2018 IPR036765 ZipA, C-terminal FtsZ-binding domain superfamily GO:0090529 VAPA_1c26010 9e8052601cdcf4b874387ff45a6f5ec5 366 Pfam PF04354 ZipA, C-terminal FtsZ-binding domain 281 336 4.0E-7 T 12-10-2018 IPR007449 ZipA, C-terminal FtsZ-binding domain GO:0090529 VAPA_1c26010 9e8052601cdcf4b874387ff45a6f5ec5 366 SMART SM00771 215 342 3.8E-16 T 12-10-2018 IPR007449 ZipA, C-terminal FtsZ-binding domain GO:0090529 VAPA_2c04730 692615dee027091beb315f0c54fb1948 406 Gene3D G3DSA:3.40.50.150 106 388 1.1E-79 T 12-10-2018 VAPA_2c04730 692615dee027091beb315f0c54fb1948 406 SUPERFAMILY SSF53335 121 388 4.65E-63 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase VAPA_2c04730 692615dee027091beb315f0c54fb1948 406 PIRSF PIRSF003085 6 405 2.6E-95 T 12-10-2018 IPR003333 Mycolic acid cyclopropane synthase GO:0008610 VAPA_2c04730 692615dee027091beb315f0c54fb1948 406 Pfam PF02353 Mycolic acid cyclopropane synthetase 116 383 9.1E-70 T 12-10-2018 VAPA_1c06760 98968773cc90dc18cf90c16067ab3039 258 Pfam PF09916 Uncharacterized protein conserved in bacteria (DUF2145) 13 214 1.4E-61 T 12-10-2018 IPR014547 Uncharacterised conserved protein UCP028477 VAPA_1c06760 98968773cc90dc18cf90c16067ab3039 258 PIRSF PIRSF028477 1 248 1.1E-90 T 12-10-2018 IPR014547 Uncharacterised conserved protein UCP028477 VAPA_1c19390 ce7d1f5fcb28cc16c362ecd7aa17193b 140 Pfam PF10696 Protein of unknown function (DUF2501) 70 139 7.8E-21 T 12-10-2018 IPR019637 Protein of unknown function DUF2501 VAPA_2c12500 14848d8cc616722482bc58e35505d703 661 SMART SM00387 557 650 5.0E-7 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase VAPA_2c12500 14848d8cc616722482bc58e35505d703 661 SUPERFAMILY SSF55874 519 648 9.17E-17 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_2c12500 14848d8cc616722482bc58e35505d703 661 Gene3D G3DSA:3.30.565.10 526 649 1.0E-24 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_1c24250 e95d67cf2e839f223bffdc5c31002129 277 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 1.6E-27 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c24250 e95d67cf2e839f223bffdc5c31002129 277 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 1.6E-27 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c24250 e95d67cf2e839f223bffdc5c31002129 277 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 217 237 1.6E-27 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c24250 e95d67cf2e839f223bffdc5c31002129 277 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 1.6E-27 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c24250 e95d67cf2e839f223bffdc5c31002129 277 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 1.6E-27 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c24250 e95d67cf2e839f223bffdc5c31002129 277 SUPERFAMILY SSF51735 1 256 8.69E-60 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c24250 e95d67cf2e839f223bffdc5c31002129 277 Gene3D G3DSA:3.40.50.720 2 276 3.4E-61 T 12-10-2018 VAPA_1c24250 e95d67cf2e839f223bffdc5c31002129 277 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 253 2.7E-34 T 12-10-2018 VAPA_1c00080 966d9572c4abeda6a6eafe01aac8c67f 415 Pfam PF00149 Calcineurin-like phosphoesterase 175 355 1.7E-9 T 12-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 VAPA_1c00080 966d9572c4abeda6a6eafe01aac8c67f 415 SUPERFAMILY SSF56300 175 410 9.01E-34 T 12-10-2018 VAPA_1c00080 966d9572c4abeda6a6eafe01aac8c67f 415 Gene3D G3DSA:3.60.21.10 174 372 2.7E-18 T 12-10-2018 IPR029052 Metallo-dependent phosphatase-like VAPA_1c23540 005e532c5f6a5581a39431fd6fec93be 366 Pfam PF03969 AFG1-like ATPase 2 355 4.3E-126 T 12-10-2018 IPR005654 ATPase, AFG1-like GO:0005524 VAPA_1c23540 005e532c5f6a5581a39431fd6fec93be 366 Gene3D G3DSA:3.40.50.300 27 189 3.4E-20 T 12-10-2018 VAPA_1c23540 005e532c5f6a5581a39431fd6fec93be 366 SUPERFAMILY SSF52540 43 178 3.22E-15 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_2c03060 6165acc9640e8adf76e56c726079876e 295 Gene3D G3DSA:3.20.20.140 13 294 2.0E-83 T 12-10-2018 VAPA_2c03060 6165acc9640e8adf76e56c726079876e 295 SUPERFAMILY SSF51556 23 292 1.07E-72 T 12-10-2018 IPR032466 Metal-dependent hydrolase VAPA_2c03060 6165acc9640e8adf76e56c726079876e 295 Pfam PF04909 Amidohydrolase 28 292 2.0E-37 T 12-10-2018 IPR006680 Amidohydrolase-related GO:0016787 VAPA_1c19940 738ee6e47dbc87f3243a7cb87fa3d692 239 Pfam PF03358 NADPH-dependent FMN reductase 33 176 9.6E-29 T 12-10-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 VAPA_1c19940 738ee6e47dbc87f3243a7cb87fa3d692 239 Gene3D G3DSA:3.40.50.360 2 239 1.5E-78 T 12-10-2018 IPR029039 Flavoprotein-like superfamily VAPA_1c19940 738ee6e47dbc87f3243a7cb87fa3d692 239 SUPERFAMILY SSF52218 6 226 2.05E-66 T 12-10-2018 IPR029039 Flavoprotein-like superfamily VAPA_1c19940 738ee6e47dbc87f3243a7cb87fa3d692 239 TIGRFAM TIGR02690 resist_ArsH: arsenical resistance protein ArsH 7 225 7.2E-128 T 12-10-2018 IPR014063 Arsenate resistance ArsH VAPA_1c42980 586056c55c5758436344a4d0b6167395 296 SUPERFAMILY SSF52540 22 253 1.11E-21 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c42980 586056c55c5758436344a4d0b6167395 296 Gene3D G3DSA:3.40.50.300 21 250 4.0E-25 T 12-10-2018 VAPA_1c46240 f589585b4c782c077874cacc4d575f16 321 Pfam PF00482 Type II secretion system (T2SS), protein F 176 304 7.6E-15 T 12-10-2018 IPR018076 Type II secretion system F domain VAPA_1c39570 02c00f804118c54efbdcb4b97f175332 262 Pfam PF00005 ABC transporter 24 162 6.2E-28 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c39570 02c00f804118c54efbdcb4b97f175332 262 SUPERFAMILY SSF52540 5 222 1.77E-63 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c39570 02c00f804118c54efbdcb4b97f175332 262 SMART SM00382 32 213 7.7E-15 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c39570 02c00f804118c54efbdcb4b97f175332 262 Gene3D G3DSA:3.40.50.300 3 259 1.1E-61 T 12-10-2018 VAPA_1c39570 02c00f804118c54efbdcb4b97f175332 262 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_1c08810 61abdfbdb05895432ff5dbd8d52298b7 368 SUPERFAMILY SSF53822 3 358 1.18E-66 T 12-10-2018 IPR028082 Periplasmic binding protein-like I VAPA_1c08810 61abdfbdb05895432ff5dbd8d52298b7 368 Gene3D G3DSA:3.40.50.2300 5 338 2.6E-89 T 12-10-2018 VAPA_1c08810 61abdfbdb05895432ff5dbd8d52298b7 368 Gene3D G3DSA:3.40.50.2300 120 350 2.6E-89 T 12-10-2018 VAPA_1c08810 61abdfbdb05895432ff5dbd8d52298b7 368 Pfam PF13458 Periplasmic binding protein 3 346 2.3E-47 T 12-10-2018 IPR028081 Leucine-binding protein domain VAPA_2c13150 0dd24c02d442ae9ad392506c279cd858 117 SUPERFAMILY SSF47413 13 72 1.38E-5 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 VAPA_2c13150 0dd24c02d442ae9ad392506c279cd858 117 Pfam PF01381 Helix-turn-helix 19 67 3.1E-5 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 VAPA_2c05960 3511b3fcedd46906f00ce4f8c12a4788 320 Gene3D G3DSA:2.60.120.650 20 244 7.1E-14 T 12-10-2018 VAPA_2c05960 3511b3fcedd46906f00ce4f8c12a4788 320 SUPERFAMILY SSF51197 31 300 3.57E-20 T 12-10-2018 VAPA_1c03520 6f8e0a69e19df22e837e8e0422ed0300 65 Pfam PF10932 Protein of unknown function (DUF2783) 6 63 1.3E-29 T 12-10-2018 IPR021233 Protein of unknown function DUF2783 VAPA_1c25850 2d69f03db660fc1c94eed931adeef435 310 Gene3D G3DSA:1.10.1040.10 178 309 2.5E-20 T 12-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 VAPA_1c25850 2d69f03db660fc1c94eed931adeef435 310 Pfam PF02558 Ketopantoate reductase PanE/ApbA 4 150 1.2E-33 T 12-10-2018 IPR013332 Ketopantoate reductase, N-terminal domain VAPA_1c25850 2d69f03db660fc1c94eed931adeef435 310 Gene3D G3DSA:3.40.50.720 1 176 3.8E-44 T 12-10-2018 VAPA_1c25850 2d69f03db660fc1c94eed931adeef435 310 Pfam PF08546 Ketopantoate reductase PanE/ApbA C terminal 178 300 1.2E-18 T 12-10-2018 IPR013752 Ketopantoate reductase, C-terminal domain VAPA_1c25850 2d69f03db660fc1c94eed931adeef435 310 TIGRFAM TIGR00745 apbA_panE: 2-dehydropantoate 2-reductase 3 304 1.8E-60 T 12-10-2018 IPR003710 Ketopantoate reductase ApbA/PanE GO:0005737|GO:0008677|GO:0015940 KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654 VAPA_1c25850 2d69f03db660fc1c94eed931adeef435 310 SUPERFAMILY SSF51735 1 121 1.79E-8 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c25850 2d69f03db660fc1c94eed931adeef435 310 SUPERFAMILY SSF48179 178 303 9.52E-24 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 VAPA_1c10270 b175c5f1c87335a0c08655d2d8af5c8e 205 Pfam PF13590 Domain of unknown function (DUF4136) 39 187 1.5E-9 T 12-10-2018 IPR025411 Domain of unknown function DUF4136 VAPA_1c10270 b175c5f1c87335a0c08655d2d8af5c8e 205 Gene3D G3DSA:3.30.160.670 20 173 2.0E-5 T 12-10-2018 VAPA_1c14180 7f0f4ac1b93351a86b697101006fde53 377 Pfam PF00155 Aminotransferase class I and II 18 331 1.3E-38 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 VAPA_1c14180 7f0f4ac1b93351a86b697101006fde53 377 SUPERFAMILY SSF53383 7 368 5.42E-72 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase VAPA_1c14180 7f0f4ac1b93351a86b697101006fde53 377 Gene3D G3DSA:3.40.640.10 48 266 1.9E-82 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 VAPA_1c14180 7f0f4ac1b93351a86b697101006fde53 377 Gene3D G3DSA:3.90.1150.10 18 354 1.9E-82 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 VAPA_1c21470 e50a87ac07afff7da605dbb50e6573af 302 Gene3D G3DSA:3.10.129.10 33 173 1.3E-8 T 12-10-2018 VAPA_1c21470 e50a87ac07afff7da605dbb50e6573af 302 Gene3D G3DSA:3.10.129.10 182 301 9.4E-16 T 12-10-2018 VAPA_1c21470 e50a87ac07afff7da605dbb50e6573af 302 SUPERFAMILY SSF54637 186 301 1.57E-16 T 12-10-2018 IPR029069 HotDog domain superfamily VAPA_1c21470 e50a87ac07afff7da605dbb50e6573af 302 Pfam PF13452 N-terminal half of MaoC dehydratase 89 152 3.0E-8 T 12-10-2018 IPR039569 N-terminal of MaoC-like dehydratase Reactome: R-HSA-193368|Reactome: R-HSA-2046106|Reactome: R-HSA-389887|Reactome: R-HSA-390247|Reactome: R-HSA-9033241|Reactome: R-HSA-9033500 VAPA_1c25970 c10239f9f426ad073234877375afa878 432 Pfam PF13657 HipA N-terminal domain 6 118 9.5E-23 T 12-10-2018 IPR017508 HipA, N-terminal subdomain 1 VAPA_1c25970 c10239f9f426ad073234877375afa878 432 TIGRFAM TIGR03071 couple_hipA: HipA N-terminal domain 69 117 1.6E-10 T 12-10-2018 IPR017508 HipA, N-terminal subdomain 1 VAPA_1c25970 c10239f9f426ad073234877375afa878 432 Pfam PF07804 HipA-like C-terminal domain 152 397 1.5E-44 T 12-10-2018 IPR012893 HipA-like, C-terminal VAPA_1c15500 baab671711b95d86a77b07894be7e485 142 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 95 136 3.1E-4 T 12-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain VAPA_1c15500 baab671711b95d86a77b07894be7e485 142 Gene3D G3DSA:3.10.180.10 20 141 1.4E-39 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase VAPA_1c15500 baab671711b95d86a77b07894be7e485 142 SUPERFAMILY SSF54593 23 140 1.61E-22 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase VAPA_1c16290 7d0ea25ee85c09ce2bd8b72eb4ac12d1 288 Gene3D G3DSA:3.40.50.1820 26 283 3.6E-54 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c16290 7d0ea25ee85c09ce2bd8b72eb4ac12d1 288 Pfam PF07859 alpha/beta hydrolase fold 69 176 1.1E-15 T 12-10-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0016787 VAPA_1c16290 7d0ea25ee85c09ce2bd8b72eb4ac12d1 288 SUPERFAMILY SSF53474 9 278 4.15E-43 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_2c03500 001a6d7805d031069ebc30c1b416bc3a 107 Pfam PF05957 Bacterial protein of unknown function (DUF883) 21 107 5.4E-12 T 12-10-2018 IPR010279 Inner membrane protein YqjD/ElaB GO:0043022 VAPA_2c08160 182ae3ed9bf21c6501fbe5f4020a3301 609 SUPERFAMILY SSF53474 219 560 1.49E-11 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_2c08160 182ae3ed9bf21c6501fbe5f4020a3301 609 Pfam PF07519 Tannase and feruloyl esterase 119 608 8.7E-83 T 12-10-2018 IPR011118 Tannase/feruloyl esterase MetaCyc: PWY-6784 VAPA_1c06650 9a67d87a5c63c60576ce8877386b7d38 626 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 45 173 3.0E-24 T 12-10-2018 IPR007387 TRAP transporter, small membrane protein DctQ VAPA_1c06650 9a67d87a5c63c60576ce8877386b7d38 626 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 212 621 6.8E-96 T 12-10-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit VAPA_1c46280 d364e2035dacc34d3fcf7fc2f2528ba9 163 Pfam PF07811 TadE-like protein 20 62 1.1E-11 T 12-10-2018 IPR012495 TadE-like VAPA_1c10460 c24882ee8a28bd7e5a1b0e8adbc84131 676 Pfam PF01464 Transglycosylase SLT domain 508 611 3.1E-23 T 12-10-2018 IPR008258 Transglycosylase SLT domain 1 VAPA_1c10460 c24882ee8a28bd7e5a1b0e8adbc84131 676 SUPERFAMILY SSF48435 44 498 1.7E-103 T 12-10-2018 IPR008939 Lytic transglycosylase, superhelical U-shaped GO:0004553|GO:0042597 VAPA_1c10460 c24882ee8a28bd7e5a1b0e8adbc84131 676 Gene3D G3DSA:1.25.20.10 46 404 4.4E-66 T 12-10-2018 VAPA_1c10460 c24882ee8a28bd7e5a1b0e8adbc84131 676 Gene3D G3DSA:1.10.530.10 494 657 1.0E-44 T 12-10-2018 VAPA_1c10460 c24882ee8a28bd7e5a1b0e8adbc84131 676 SUPERFAMILY SSF53955 499 657 1.22E-46 T 12-10-2018 IPR023346 Lysozyme-like domain superfamily VAPA_1c08370 88af8c647b7bdc92736d80eeea531cb0 599 Gene3D G3DSA:3.90.550.10 309 551 4.0E-45 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases VAPA_1c08370 88af8c647b7bdc92736d80eeea531cb0 599 SUPERFAMILY SSF53448 56 256 6.3E-10 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases VAPA_1c08370 88af8c647b7bdc92736d80eeea531cb0 599 SUPERFAMILY SSF53448 316 558 8.91E-46 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases VAPA_1c08370 88af8c647b7bdc92736d80eeea531cb0 599 Gene3D G3DSA:3.90.550.10 66 276 7.6E-9 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases VAPA_1c08370 88af8c647b7bdc92736d80eeea531cb0 599 Pfam PF00535 Glycosyl transferase family 2 317 495 2.5E-19 T 12-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 VAPA_1c05030 90c7c1c0aa47198d0fbf0cebc8ad614d 173 Gene3D G3DSA:3.30.160.150 43 173 1.1E-41 T 12-10-2018 VAPA_1c05030 90c7c1c0aa47198d0fbf0cebc8ad614d 173 Hamap MF_01186 LPS-assembly lipoprotein LptE [lptE]. 14 172 22.269 T 12-10-2018 IPR007485 LPS-assembly lipoprotein LptE GO:0019867|GO:0043165 VAPA_1c05030 90c7c1c0aa47198d0fbf0cebc8ad614d 173 Pfam PF04390 Lipopolysaccharide-assembly 42 167 2.3E-12 T 12-10-2018 IPR007485 LPS-assembly lipoprotein LptE GO:0019867|GO:0043165 VAPA_1c33100 ef2b0df1d1a1fcb31c214827f6ecb958 567 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 124 134 - T 12-10-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 VAPA_1c33100 ef2b0df1d1a1fcb31c214827f6ecb958 567 SUPERFAMILY SSF143975 4 373 1.96E-98 T 12-10-2018 IPR037237 IlvD/EDD, N-terminal domain KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 VAPA_1c33100 ef2b0df1d1a1fcb31c214827f6ecb958 567 SUPERFAMILY SSF52016 377 558 2.35E-42 T 12-10-2018 VAPA_1c33100 ef2b0df1d1a1fcb31c214827f6ecb958 567 Pfam PF00920 Dehydratase family 36 555 5.9E-155 T 12-10-2018 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 VAPA_1c33100 ef2b0df1d1a1fcb31c214827f6ecb958 567 Gene3D G3DSA:3.50.30.80 376 529 3.4E-38 T 12-10-2018 VAPA_1c43850 8a5ce2f6c9312de4e11e893f2e1184dc 70 Gene3D G3DSA:3.30.50.10 8 68 2.7E-19 T 12-10-2018 IPR013088 Zinc finger, NHR/GATA-type GO:0006355|GO:0008270 Reactome: R-HSA-383280 VAPA_1c43850 8a5ce2f6c9312de4e11e893f2e1184dc 70 Hamap MF_00649 DNA gyrase inhibitor YacG [yacG]. 8 62 15.991 T 12-10-2018 IPR005584 DNA gyrase inhibitor YacG GO:0008270 VAPA_1c43850 8a5ce2f6c9312de4e11e893f2e1184dc 70 Pfam PF03884 DNA gyrase inhibitor YacG 12 61 1.9E-22 T 12-10-2018 IPR005584 DNA gyrase inhibitor YacG GO:0008270 VAPA_1c43850 8a5ce2f6c9312de4e11e893f2e1184dc 70 SUPERFAMILY SSF57716 10 65 2.14E-17 T 12-10-2018 VAPA_2c13070 6bdfd81d671e0947b4686caf6672b24e 387 Pfam PF06250 Protein of unknown function (DUF1016) 17 362 8.1E-110 T 12-10-2018 IPR009362 Protein of unknown function DUF1016 VAPA_1c26140 9e3406db2695a59fcdf00d5377f2cda4 261 Pfam PF13616 PPIC-type PPIASE domain 130 223 2.9E-24 T 12-10-2018 VAPA_1c26140 9e3406db2695a59fcdf00d5377f2cda4 261 SUPERFAMILY SSF54534 131 225 1.37E-29 T 12-10-2018 VAPA_1c26140 9e3406db2695a59fcdf00d5377f2cda4 261 SUPERFAMILY SSF109998 26 161 1.61E-19 T 12-10-2018 IPR027304 Trigger factor/SurA domain superfamily VAPA_1c26140 9e3406db2695a59fcdf00d5377f2cda4 261 Gene3D G3DSA:3.10.50.40 126 248 1.8E-34 T 12-10-2018 VAPA_1c45940 0353d14ad94b35f8895485ac8eaf100a 383 SUPERFAMILY SSF117892 187 313 6.28E-25 T 12-10-2018 IPR036013 Band 7/SPFH domain superfamily VAPA_1c45940 0353d14ad94b35f8895485ac8eaf100a 383 PRINTS PR00721 Stomatin signature 302 323 6.3E-15 T 12-10-2018 IPR001972 Stomatin family GO:0016020 VAPA_1c45940 0353d14ad94b35f8895485ac8eaf100a 383 PRINTS PR00721 Stomatin signature 204 225 6.3E-15 T 12-10-2018 IPR001972 Stomatin family GO:0016020 VAPA_1c45940 0353d14ad94b35f8895485ac8eaf100a 383 PRINTS PR00721 Stomatin signature 327 350 6.3E-15 T 12-10-2018 IPR001972 Stomatin family GO:0016020 VAPA_1c45940 0353d14ad94b35f8895485ac8eaf100a 383 PRINTS PR00721 Stomatin signature 239 256 6.3E-15 T 12-10-2018 IPR001972 Stomatin family GO:0016020 VAPA_1c45940 0353d14ad94b35f8895485ac8eaf100a 383 PRINTS PR00721 Stomatin signature 283 301 6.3E-15 T 12-10-2018 IPR001972 Stomatin family GO:0016020 VAPA_1c45940 0353d14ad94b35f8895485ac8eaf100a 383 Gene3D G3DSA:3.30.479.30 185 309 3.1E-23 T 12-10-2018 VAPA_1c45940 0353d14ad94b35f8895485ac8eaf100a 383 Pfam PF01145 SPFH domain / Band 7 family 152 323 4.7E-24 T 12-10-2018 IPR001107 Band 7 domain VAPA_1c45940 0353d14ad94b35f8895485ac8eaf100a 383 SMART SM00244 148 307 1.2E-13 T 12-10-2018 IPR001107 Band 7 domain VAPA_2c11860 36a755fd91c43883d3e6258ce8020e24 328 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 51 324 5.1E-92 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_2c11860 36a755fd91c43883d3e6258ce8020e24 328 SUPERFAMILY SSF53850 117 290 1.68E-11 T 12-10-2018 VAPA_2c11860 36a755fd91c43883d3e6258ce8020e24 328 Gene3D G3DSA:3.40.190.150 32 318 1.1E-114 T 12-10-2018 VAPA_2c11860 36a755fd91c43883d3e6258ce8020e24 328 Gene3D G3DSA:3.40.190.10 129 253 1.1E-114 T 12-10-2018 VAPA_2c11860 36a755fd91c43883d3e6258ce8020e24 328 PIRSF PIRSF017082 1 327 3.4E-82 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_2c01210 0f21bbc9682640aee17d10e04517594e 495 Pfam PF08887 GAD-like domain 37 124 1.9E-13 T 12-10-2018 IPR014983 GAD-related VAPA_1c53280 217834f9cdd760a83681ba04c202202c 196 Pfam PF02525 Flavodoxin-like fold 1 193 1.1E-33 T 12-10-2018 IPR003680 Flavodoxin-like fold VAPA_1c53280 217834f9cdd760a83681ba04c202202c 196 SUPERFAMILY SSF52218 1 196 1.32E-41 T 12-10-2018 IPR029039 Flavoprotein-like superfamily VAPA_1c53280 217834f9cdd760a83681ba04c202202c 196 Gene3D G3DSA:3.40.50.360 1 196 2.2E-41 T 12-10-2018 IPR029039 Flavoprotein-like superfamily VAPA_1c05590 5c1a5101634354d51afffd22e336e918 574 Gene3D G3DSA:3.20.20.70 171 529 4.2E-106 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 VAPA_1c05590 5c1a5101634354d51afffd22e336e918 574 Pfam PF01645 Conserved region in glutamate synthase 181 498 7.2E-82 T 12-10-2018 IPR002932 Glutamate synthase domain GO:0006537|GO:0015930|GO:0016638|GO:0055114 VAPA_1c05590 5c1a5101634354d51afffd22e336e918 574 SUPERFAMILY SSF51395 23 527 3.09E-132 T 12-10-2018 VAPA_1c05590 5c1a5101634354d51afffd22e336e918 574 PIRSF PIRSF006429 9 566 7.2E-161 T 12-10-2018 IPR024188 Glutamate synthase large subunit-like protein VAPA_1c05590 5c1a5101634354d51afffd22e336e918 574 PIRSF PIRSF500060 15 556 3.4E-226 T 12-10-2018 IPR027283 Glutamate synthase large subunit-like protein, bacteria VAPA_1c14340 8dd7b0ca196906b10593e4c3d691c81a 141 Pfam PF00583 Acetyltransferase (GNAT) family 38 118 1.4E-12 T 12-10-2018 IPR000182 GNAT domain VAPA_1c14340 8dd7b0ca196906b10593e4c3d691c81a 141 Gene3D G3DSA:3.40.630.30 1 134 7.0E-26 T 12-10-2018 VAPA_1c14340 8dd7b0ca196906b10593e4c3d691c81a 141 SUPERFAMILY SSF55729 13 124 2.49E-20 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase VAPA_1c33180 f5094ecee38b8c51405fc1eab32f86f9 276 Pfam PF02900 Catalytic LigB subunit of aromatic ring-opening dioxygenase 32 271 1.0E-42 T 12-10-2018 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 VAPA_1c33180 f5094ecee38b8c51405fc1eab32f86f9 276 Gene3D G3DSA:3.40.830.10 2 272 1.5E-89 T 12-10-2018 VAPA_1c33180 f5094ecee38b8c51405fc1eab32f86f9 276 SUPERFAMILY SSF53213 9 272 1.57E-86 T 12-10-2018 VAPA_1c33180 f5094ecee38b8c51405fc1eab32f86f9 276 PIRSF PIRSF006157 6 273 2.5E-90 T 12-10-2018 IPR014436 Extradiol aromatic ring-opening dioxygenase, DODA-type GO:0008270|GO:0016701|GO:0055114 VAPA_2c08880 2f364b661ec517ff233463e13921b9e4 226 SUPERFAMILY SSF55469 8 224 2.09E-43 T 12-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 VAPA_2c08880 2f364b661ec517ff233463e13921b9e4 226 Gene3D G3DSA:3.40.109.10 3 222 7.1E-57 T 12-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 VAPA_2c08880 2f364b661ec517ff233463e13921b9e4 226 Pfam PF00881 Nitroreductase family 11 201 6.0E-33 T 12-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 VAPA_1c17160 a5899e675cb13d400fef8c8728d390c2 218 SUPERFAMILY SSF103088 102 211 7.46E-38 T 12-10-2018 IPR036737 OmpA-like domain superfamily VAPA_1c17160 a5899e675cb13d400fef8c8728d390c2 218 Pfam PF00691 OmpA family 110 205 3.5E-23 T 12-10-2018 IPR006665 OmpA-like domain VAPA_1c17160 a5899e675cb13d400fef8c8728d390c2 218 Gene3D G3DSA:3.30.1330.60 85 217 1.6E-42 T 12-10-2018 IPR036737 OmpA-like domain superfamily VAPA_1c17160 a5899e675cb13d400fef8c8728d390c2 218 PRINTS PR01021 OMPA domain signature 111 133 1.1E-18 T 12-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 VAPA_1c17160 a5899e675cb13d400fef8c8728d390c2 218 PRINTS PR01021 OMPA domain signature 156 172 1.1E-18 T 12-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 VAPA_1c17160 a5899e675cb13d400fef8c8728d390c2 218 PRINTS PR01021 OMPA domain signature 141 156 1.1E-18 T 12-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 VAPA_1c52950 9540543c106e2169aed43b87142bd946 373 SUPERFAMILY SSF53474 30 370 1.69E-15 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c16710 775548a1aa5e00bdf6ce192d05a6ac1f 479 Pfam PF00083 Sugar (and other) transporter 61 448 1.7E-47 T 12-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 VAPA_1c16710 775548a1aa5e00bdf6ce192d05a6ac1f 479 SUPERFAMILY SSF103473 8 459 1.83E-74 T 12-10-2018 IPR036259 MFS transporter superfamily VAPA_1c16710 775548a1aa5e00bdf6ce192d05a6ac1f 479 Gene3D G3DSA:1.20.1250.20 18 469 2.3E-77 T 12-10-2018 VAPA_1c12910 d94f55a59f9c2ed41ba9d9f9420d22b3 186 Pfam PF04191 Phospholipid methyltransferase 63 165 3.5E-10 T 12-10-2018 IPR007318 Phospholipid methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825|Reactome: R-HSA-1483191 VAPA_1c12910 d94f55a59f9c2ed41ba9d9f9420d22b3 186 Gene3D G3DSA:1.20.120.1630 1 186 5.2E-23 T 12-10-2018 VAPA_1c43880 07b5ca2f8a0c5914b8d96e479999816a 291 Pfam PF05673 Protein of unknown function (DUF815) 36 288 1.2E-103 T 12-10-2018 IPR008533 Domain of unknown function DUF815 VAPA_1c43880 07b5ca2f8a0c5914b8d96e479999816a 291 SUPERFAMILY SSF52540 48 196 5.26E-26 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c43880 07b5ca2f8a0c5914b8d96e479999816a 291 Gene3D G3DSA:3.40.50.300 57 199 7.6E-10 T 12-10-2018 VAPA_1c47410 fa832e65d52a8d37bff29458d258093a 448 Gene3D G3DSA:3.30.870.10 7 155 7.5E-11 T 12-10-2018 VAPA_1c47410 fa832e65d52a8d37bff29458d258093a 448 SUPERFAMILY SSF56024 67 127 8.05E-8 T 12-10-2018 VAPA_2c10680 cdb76eb65d373204c13b2a4ed6572a53 185 SUPERFAMILY SSF54593 10 133 3.76E-27 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase VAPA_2c10680 cdb76eb65d373204c13b2a4ed6572a53 185 ProSitePatterns PS00082 Extradiol ring-cleavage dioxygenases signature. 106 125 - T 12-10-2018 IPR000486 Extradiol ring-cleavage dioxygenase, class I /II GO:0003824|GO:0006725|GO:0008198|GO:0055114 VAPA_2c10680 cdb76eb65d373204c13b2a4ed6572a53 185 Gene3D G3DSA:3.10.180.10 10 183 8.1E-32 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase VAPA_2c10680 cdb76eb65d373204c13b2a4ed6572a53 185 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 11 126 1.6E-12 T 12-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain VAPA_1c03670 241a38c163a144106331633fdbe170ae 357 SUPERFAMILY SSF53850 37 354 7.09E-57 T 12-10-2018 VAPA_1c03670 241a38c163a144106331633fdbe170ae 357 Gene3D G3DSA:3.40.190.10 52 322 2.8E-67 T 12-10-2018 VAPA_1c03670 241a38c163a144106331633fdbe170ae 357 Pfam PF13416 Bacterial extracellular solute-binding protein 58 316 6.6E-28 T 12-10-2018 IPR006059 Bacterial extracellular solute-binding protein VAPA_1c03670 241a38c163a144106331633fdbe170ae 357 Gene3D G3DSA:3.40.190.10 139 351 2.8E-67 T 12-10-2018 VAPA_1c12880 1b071bd1319dcb67e10f1c7561d4df13 340 Pfam PF00535 Glycosyl transferase family 2 31 192 1.1E-33 T 12-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 VAPA_1c12880 1b071bd1319dcb67e10f1c7561d4df13 340 SUPERFAMILY SSF53448 26 255 4.31E-40 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases VAPA_1c12880 1b071bd1319dcb67e10f1c7561d4df13 340 Gene3D G3DSA:3.90.550.10 12 218 1.5E-38 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases VAPA_2c02900 6feb5f7da12f820223c93d38791a40fd 228 Pfam PF03737 Aldolase/RraA 23 184 3.9E-29 T 12-10-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein VAPA_2c02900 6feb5f7da12f820223c93d38791a40fd 228 SUPERFAMILY SSF89562 21 193 3.79E-32 T 12-10-2018 IPR036704 Ribonuclease E inhibitor RraA/RraA-like superfamily VAPA_2c02900 6feb5f7da12f820223c93d38791a40fd 228 Gene3D G3DSA:3.50.30.100 1 208 4.8E-57 T 12-10-2018 VAPA_2c06850 ea9882bc281e24fb5735fe1d7b446f96 325 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 49 321 3.5E-72 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_2c06850 ea9882bc281e24fb5735fe1d7b446f96 325 Gene3D G3DSA:3.40.190.10 125 248 3.6E-95 T 12-10-2018 VAPA_2c06850 ea9882bc281e24fb5735fe1d7b446f96 325 Gene3D G3DSA:3.40.190.150 29 314 3.6E-95 T 12-10-2018 VAPA_2c06850 ea9882bc281e24fb5735fe1d7b446f96 325 SUPERFAMILY SSF53850 104 280 5.7E-8 T 12-10-2018 VAPA_2c06850 ea9882bc281e24fb5735fe1d7b446f96 325 PIRSF PIRSF017082 1 324 1.7E-72 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c08320 f8403d93d48fb856bee73bc71b844353 677 Pfam PF01757 Acyltransferase family 23 345 3.3E-26 T 12-10-2018 IPR002656 Acyltransferase 3 GO:0016747 VAPA_1c35640 bcd73cb6a7344ccf2c70693577be1aa6 318 Gene3D G3DSA:3.40.190.150 24 305 4.4E-96 T 12-10-2018 VAPA_1c35640 bcd73cb6a7344ccf2c70693577be1aa6 318 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 41 314 1.4E-70 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c35640 bcd73cb6a7344ccf2c70693577be1aa6 318 Gene3D G3DSA:3.40.190.10 119 243 4.4E-96 T 12-10-2018 VAPA_1c35640 bcd73cb6a7344ccf2c70693577be1aa6 318 SUPERFAMILY SSF53850 105 278 2.17E-6 T 12-10-2018 VAPA_1c35640 bcd73cb6a7344ccf2c70693577be1aa6 318 PIRSF PIRSF017082 2 318 1.1E-69 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_2c08490 a176ae646e9c5f8313b74fc09de29455 100 Gene3D G3DSA:1.20.1270.180 38 99 1.2E-6 T 12-10-2018 VAPA_2c08490 a176ae646e9c5f8313b74fc09de29455 100 Pfam PF07007 Lysozyme inhibitor LprI 54 96 8.6E-6 T 12-10-2018 IPR009739 Lysozyme inhibitor LprI, N-terminal VAPA_1c19910 8a857a1e8c5dca5b8170f855a79ffb5d 161 SUPERFAMILY SSF52788 3 144 1.13E-37 T 12-10-2018 IPR036196 Phosphotyrosine protein phosphatase I superfamily VAPA_1c19910 8a857a1e8c5dca5b8170f855a79ffb5d 161 Gene3D G3DSA:3.40.50.2300 2 145 7.3E-41 T 12-10-2018 VAPA_1c19910 8a857a1e8c5dca5b8170f855a79ffb5d 161 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 5 141 2.1E-19 T 12-10-2018 IPR023485 Phosphotyrosine protein phosphatase I VAPA_1c19910 8a857a1e8c5dca5b8170f855a79ffb5d 161 SMART SM00226 3 144 3.6E-30 T 12-10-2018 IPR023485 Phosphotyrosine protein phosphatase I VAPA_1c11200 a530c4a1f3a0fd9970ac03c9d595e046 417 Gene3D G3DSA:1.20.1250.20 3 411 5.9E-49 T 12-10-2018 VAPA_1c11200 a530c4a1f3a0fd9970ac03c9d595e046 417 Pfam PF07690 Major Facilitator Superfamily 25 291 3.9E-26 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 VAPA_1c11200 a530c4a1f3a0fd9970ac03c9d595e046 417 SUPERFAMILY SSF103473 11 412 4.58E-55 T 12-10-2018 IPR036259 MFS transporter superfamily VAPA_1c51220 f3680e67f0137d8aac36b9ab26c91b7a 291 Pfam PF02653 Branched-chain amino acid transport system / permease component 7 275 1.3E-35 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 VAPA_1c07780 db1cb90f6f3f772893832ed6c749ef00 340 Pfam PF03547 Membrane transport protein 163 334 1.4E-15 T 12-10-2018 IPR004776 Membrane transport protein GO:0016021|GO:0055085 VAPA_1c07780 db1cb90f6f3f772893832ed6c749ef00 340 Pfam PF03547 Membrane transport protein 9 134 2.5E-15 T 12-10-2018 IPR004776 Membrane transport protein GO:0016021|GO:0055085 VAPA_1c11240 cbaddd72c7b29d3355223042bf8083e4 299 Pfam PF06189 5'-nucleotidase 39 297 4.4E-103 T 12-10-2018 IPR010394 5-nucleotidase GO:0000166|GO:0000287|GO:0005737|GO:0008253|GO:0009117 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821|Reactome: R-HSA-74259 VAPA_1c41280 d15eccbe65f3af52da72b738b865dabc 278 Gene3D G3DSA:3.40.50.1820 52 255 9.0E-26 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c41280 d15eccbe65f3af52da72b738b865dabc 278 Pfam PF12146 Serine aminopeptidase, S33 82 165 2.4E-7 T 12-10-2018 IPR022742 Serine aminopeptidase, S33 VAPA_1c41280 d15eccbe65f3af52da72b738b865dabc 278 SUPERFAMILY SSF53474 53 266 1.08E-24 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c06000 865166f27a0169d81a774afd528f3b7d 658 Gene3D G3DSA:3.40.50.1460 24 310 4.3E-35 T 12-10-2018 VAPA_1c06000 865166f27a0169d81a774afd528f3b7d 658 Pfam PF00656 Caspase domain 26 181 9.2E-14 T 12-10-2018 VAPA_2c06020 69a8ea72d2d2235352ab3f316c856a45 145 Pfam PF00571 CBS domain 73 123 8.2E-11 T 12-10-2018 IPR000644 CBS domain VAPA_2c06020 69a8ea72d2d2235352ab3f316c856a45 145 Pfam PF00571 CBS domain 10 61 2.0E-6 T 12-10-2018 IPR000644 CBS domain VAPA_2c06020 69a8ea72d2d2235352ab3f316c856a45 145 Gene3D G3DSA:3.10.580.10 2 138 5.4E-33 T 12-10-2018 VAPA_2c06020 69a8ea72d2d2235352ab3f316c856a45 145 SMART SM00116 14 62 0.15 T 12-10-2018 IPR000644 CBS domain VAPA_2c06020 69a8ea72d2d2235352ab3f316c856a45 145 SMART SM00116 80 127 8.7E-7 T 12-10-2018 IPR000644 CBS domain VAPA_2c06020 69a8ea72d2d2235352ab3f316c856a45 145 SUPERFAMILY SSF54631 10 123 9.6E-28 T 12-10-2018 VAPA_1c04760 aeb2043c1572f90901a64a0990e96e11 437 Pfam PF13701 Transposase DDE domain group 1 14 435 5.6E-149 T 12-10-2018 IPR025668 Transposase DDE domain VAPA_1c02690 aeb2043c1572f90901a64a0990e96e11 437 Pfam PF13701 Transposase DDE domain group 1 14 435 5.6E-149 T 12-10-2018 IPR025668 Transposase DDE domain VAPA_1c29550 5094269bb2b59a545db3bf6bdfca993a 417 Pfam PF01266 FAD dependent oxidoreductase 2 397 1.8E-58 T 12-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 VAPA_1c29550 5094269bb2b59a545db3bf6bdfca993a 417 Gene3D G3DSA:3.50.50.60 85 398 1.6E-43 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c29550 5094269bb2b59a545db3bf6bdfca993a 417 SUPERFAMILY SSF51905 1 415 1.29E-43 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c29550 5094269bb2b59a545db3bf6bdfca993a 417 Gene3D G3DSA:3.50.50.60 3 54 4.7E-11 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c29550 5094269bb2b59a545db3bf6bdfca993a 417 SUPERFAMILY SSF54373 269 359 9.81E-8 T 12-10-2018 VAPA_1c29550 5094269bb2b59a545db3bf6bdfca993a 417 Gene3D G3DSA:3.30.9.10 133 358 1.6E-43 T 12-10-2018 VAPA_1c29840 4bbafa92672e9537a71e5936539e1855 269 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 162 202 - T 12-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 VAPA_1c29840 4bbafa92672e9537a71e5936539e1855 269 SMART SM00342 173 257 4.7E-12 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 VAPA_1c29840 4bbafa92672e9537a71e5936539e1855 269 Pfam PF12833 Helix-turn-helix domain 180 258 1.4E-16 T 12-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 VAPA_1c29840 4bbafa92672e9537a71e5936539e1855 269 Gene3D G3DSA:1.10.10.60 161 261 1.2E-17 T 12-10-2018 VAPA_1c26630 1ad24621dc482032f103521420f703a6 210 SUPERFAMILY SSF159594 28 198 8.11E-26 T 12-10-2018 VAPA_1c26630 1ad24621dc482032f103521420f703a6 210 Pfam PF03886 ABC-type transport auxiliary lipoprotein component 30 193 1.4E-31 T 12-10-2018 IPR005586 ABC-type transport auxiliary lipoprotein component VAPA_1c05550 43191fe7d4a4fb8da722c295ef9615dd 160 Pfam PF14113 Type VI secretion system (T6SS), amidase effector protein 4 27 157 2.2E-24 T 12-10-2018 IPR025562 Type VI secretion system (T6SS), amidase effector protein 4 VAPA_1c05550 43191fe7d4a4fb8da722c295ef9615dd 160 Gene3D G3DSA:3.90.1720.70 1 142 4.8E-11 T 12-10-2018 VAPA_1c51880 fd778834031b79b64939bd7952c1e525 125 SUPERFAMILY SSF54593 5 123 3.62E-21 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase VAPA_1c51880 fd778834031b79b64939bd7952c1e525 125 Gene3D G3DSA:3.10.180.10 3 124 6.4E-21 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase VAPA_1c51880 fd778834031b79b64939bd7952c1e525 125 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 7 120 4.7E-7 T 12-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain VAPA_1c51050 bde645a6f5693f4c2b695f1c5726f223 117 Gene3D G3DSA:3.40.30.10 13 115 1.9E-29 T 12-10-2018 VAPA_1c51050 bde645a6f5693f4c2b695f1c5726f223 117 SUPERFAMILY SSF52833 15 112 1.01E-25 T 12-10-2018 IPR036249 Thioredoxin-like superfamily VAPA_2c10240 019387b186f02f5f70de95f878c85360 402 SUPERFAMILY SSF89796 12 401 2.09E-117 T 12-10-2018 IPR023606 CoA-transferase family III domain superfamily VAPA_2c10240 019387b186f02f5f70de95f878c85360 402 Gene3D G3DSA:3.30.1540.10 231 323 1.2E-113 T 12-10-2018 VAPA_2c10240 019387b186f02f5f70de95f878c85360 402 Gene3D G3DSA:3.40.50.10540 14 352 1.2E-113 T 12-10-2018 IPR023606 CoA-transferase family III domain superfamily VAPA_2c10240 019387b186f02f5f70de95f878c85360 402 Pfam PF02515 CoA-transferase family III 15 378 3.8E-121 T 12-10-2018 IPR003673 CoA-transferase family III GO:0003824 VAPA_1c11530 8d95d1d044cd602807adcefb55e00ec4 337 SUPERFAMILY SSF53850 19 329 2.49E-71 T 12-10-2018 VAPA_1c11530 8d95d1d044cd602807adcefb55e00ec4 337 Gene3D G3DSA:3.40.190.10 27 299 4.0E-101 T 12-10-2018 VAPA_1c11530 8d95d1d044cd602807adcefb55e00ec4 337 PIRSF PIRSF002825 3 333 1.1E-64 T 12-10-2018 IPR026045 Ferric binding protein VAPA_1c11530 8d95d1d044cd602807adcefb55e00ec4 337 Pfam PF13343 Bacterial extracellular solute-binding protein 69 314 1.4E-36 T 12-10-2018 VAPA_1c11530 8d95d1d044cd602807adcefb55e00ec4 337 Gene3D G3DSA:3.40.190.10 127 313 4.0E-101 T 12-10-2018 VAPA_2c05340 62130266fae5e64f2ee392236eccdbcf 484 Pfam PF00361 Proton-conducting membrane transporter 125 418 1.9E-52 T 12-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VAPA_2c05340 62130266fae5e64f2ee392236eccdbcf 484 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 130 149 4.7E-12 T 12-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VAPA_2c05340 62130266fae5e64f2ee392236eccdbcf 484 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 380 406 4.7E-12 T 12-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VAPA_2c05340 62130266fae5e64f2ee392236eccdbcf 484 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 328 347 4.7E-12 T 12-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VAPA_2c05340 62130266fae5e64f2ee392236eccdbcf 484 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 239 263 4.7E-12 T 12-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VAPA_2c05110 24b440eb8ea06cfdcc7d0afd91b55cb4 144 Pfam PF13211 Protein of unknown function (DUF4019) 37 141 7.6E-23 T 12-10-2018 IPR025091 Protein of unknown function DUF4019 VAPA_1c29060 406f2a36dc5279b66d5881c6494b03c2 152 Pfam PF02643 Uncharacterized ACR, COG1430 41 142 2.7E-31 T 12-10-2018 IPR003795 Protein of unknown function DUF192 VAPA_1c29060 406f2a36dc5279b66d5881c6494b03c2 152 Gene3D G3DSA:2.60.120.1140 21 151 2.4E-38 T 12-10-2018 IPR038695 Saro_0823-like superfamily VAPA_1c23460 adbff530658679018d91907dbe15fdc1 264 SUPERFAMILY SSF53474 48 257 3.33E-17 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c23460 adbff530658679018d91907dbe15fdc1 264 Gene3D G3DSA:3.40.50.1820 43 259 1.2E-15 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c20360 3f7e7e3817b76adca590261253f393cd 352 Pfam PF05853 beta-keto acid cleavage enzyme 15 319 7.9E-65 T 12-10-2018 IPR008567 3-keto-5-aminohexanoate cleavage enzyme GO:0016740|GO:0019475 KEGG: 00310+2.3.1.247 VAPA_1c20360 3f7e7e3817b76adca590261253f393cd 352 Gene3D G3DSA:3.20.20.70 10 324 3.1E-68 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 VAPA_1c33220 9bba8e62f845caa5c01302ee73b3c30a 206 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 24 37 4.0E-11 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 VAPA_1c33220 9bba8e62f845caa5c01302ee73b3c30a 206 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 45 68 4.0E-11 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 VAPA_1c33220 9bba8e62f845caa5c01302ee73b3c30a 206 Gene3D G3DSA:1.10.357.10 9 199 2.5E-33 T 12-10-2018 VAPA_1c33220 9bba8e62f845caa5c01302ee73b3c30a 206 Pfam PF00440 Bacterial regulatory proteins, tetR family 24 70 6.0E-17 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 VAPA_1c33220 9bba8e62f845caa5c01302ee73b3c30a 206 ProSitePatterns PS01081 TetR-type HTH domain signature. 36 66 - T 12-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site VAPA_1c33220 9bba8e62f845caa5c01302ee73b3c30a 206 SUPERFAMILY SSF46689 11 96 3.23E-19 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 VAPA_1c11020 53e85d5b41f2072a1731394fceb0bb77 344 Pfam PF02653 Branched-chain amino acid transport system / permease component 47 319 2.9E-40 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 VAPA_1c22760 8c163e9b77ed5a93410e9b39d82610d1 325 Pfam PF05598 Transposase domain (DUF772) 50 123 1.4E-20 T 12-10-2018 IPR008490 Transposase InsH, N-terminal VAPA_1c22760 8c163e9b77ed5a93410e9b39d82610d1 325 Pfam PF01609 Transposase DDE domain 135 306 5.2E-28 T 12-10-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 VAPA_2c09270 8c163e9b77ed5a93410e9b39d82610d1 325 Pfam PF05598 Transposase domain (DUF772) 50 123 1.4E-20 T 12-10-2018 IPR008490 Transposase InsH, N-terminal VAPA_2c09270 8c163e9b77ed5a93410e9b39d82610d1 325 Pfam PF01609 Transposase DDE domain 135 306 5.2E-28 T 12-10-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 VAPA_1c36580 dc813b85d76829d1cde98d22cce34c81 156 Gene3D G3DSA:2.60.120.10 24 155 6.0E-17 T 12-10-2018 IPR014710 RmlC-like jelly roll fold VAPA_1c36580 dc813b85d76829d1cde98d22cce34c81 156 SUPERFAMILY SSF51182 28 155 1.38E-19 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily VAPA_1c54980 223de37a99d14f19c2d8f3bb50377210 195 Gene3D G3DSA:3.40.50.150 6 178 1.6E-25 T 12-10-2018 VAPA_1c54980 223de37a99d14f19c2d8f3bb50377210 195 TIGRFAM TIGR02081 metW: methionine biosynthesis protein MetW 8 191 5.5E-70 T 12-10-2018 IPR010743 Methionine biosynthesis MetW KEGG: 00270+2.3.1.31|MetaCyc: PWY-5344 VAPA_1c54980 223de37a99d14f19c2d8f3bb50377210 195 Pfam PF07021 Methionine biosynthesis protein MetW 8 190 4.4E-64 T 12-10-2018 IPR010743 Methionine biosynthesis MetW KEGG: 00270+2.3.1.31|MetaCyc: PWY-5344 VAPA_1c54980 223de37a99d14f19c2d8f3bb50377210 195 SUPERFAMILY SSF53335 8 172 6.29E-26 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase VAPA_1c45010 84f67d5668f11613fd59a868ed227eac 196 TIGRFAM TIGR00455 apsK: adenylyl-sulfate kinase 22 184 9.4E-64 T 12-10-2018 IPR002891 Adenylyl-sulfate kinase GO:0000103|GO:0004020|GO:0005524 KEGG: 00230+2.7.1.25|KEGG: 00920+2.7.1.25|MetaCyc: PWY-5340|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 VAPA_1c45010 84f67d5668f11613fd59a868ed227eac 196 Hamap MF_00065 Adenylyl-sulfate kinase [cysC]. 18 189 34.159 T 12-10-2018 IPR002891 Adenylyl-sulfate kinase GO:0000103|GO:0004020|GO:0005524 KEGG: 00230+2.7.1.25|KEGG: 00920+2.7.1.25|MetaCyc: PWY-5340|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 VAPA_1c45010 84f67d5668f11613fd59a868ed227eac 196 SUPERFAMILY SSF52540 12 185 1.44E-37 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c45010 84f67d5668f11613fd59a868ed227eac 196 Pfam PF01583 Adenylylsulphate kinase 22 172 4.6E-61 T 12-10-2018 VAPA_1c45010 84f67d5668f11613fd59a868ed227eac 196 Gene3D G3DSA:3.40.50.300 5 189 1.5E-65 T 12-10-2018 VAPA_1c27270 c3596ca848281bf10bf036fb0ecc7c49 230 Pfam PF13386 Cytochrome C biogenesis protein transmembrane region 6 212 5.4E-33 T 12-10-2018 IPR039447 Urease accessory protein UreH-like, transmembrane domain VAPA_1c11140 3fd31ac1c3b4bb3428e2f69cb968517e 158 Pfam PF08909 Domain of unknown function (DUF1854) 28 157 5.3E-47 T 12-10-2018 IPR015005 Domain of unknown function DUF1854 VAPA_1c46050 1e06dd7fa01e05d918282bed13f35a47 190 Gene3D G3DSA:3.40.30.10 23 181 3.2E-48 T 12-10-2018 VAPA_1c46050 1e06dd7fa01e05d918282bed13f35a47 190 SUPERFAMILY SSF52833 37 176 1.03E-34 T 12-10-2018 IPR036249 Thioredoxin-like superfamily VAPA_1c46050 1e06dd7fa01e05d918282bed13f35a47 190 Pfam PF08534 Redoxin 36 173 2.9E-13 T 12-10-2018 IPR013740 Redoxin GO:0016491 Reactome: R-HSA-3299685|Reactome: R-HSA-5628897 VAPA_2c04930 f08a83e9e9b12a98792712033ae9cd01 134 SUPERFAMILY SSF46626 17 97 1.21E-7 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 VAPA_2c00370 e7597e7e527313e12489c8cba4898526 216 Gene3D G3DSA:2.60.120.330 10 203 1.4E-16 T 12-10-2018 IPR027443 Isopenicillin N synthase-like VAPA_2c00370 e7597e7e527313e12489c8cba4898526 216 SUPERFAMILY SSF51197 85 192 3.3E-12 T 12-10-2018 VAPA_2c00370 e7597e7e527313e12489c8cba4898526 216 Pfam PF05118 Aspartyl/Asparaginyl beta-hydroxylase 85 186 3.7E-7 T 12-10-2018 IPR007803 Aspartyl/asparaginy/proline hydroxylase GO:0018193 VAPA_1c43270 52924ba138a80c787b21d2642b3333e8 236 Pfam PF02108 Flagellar assembly protein FliH 97 223 9.6E-37 T 12-10-2018 IPR018035 Flagellar assembly protein FliH/Type III secretion system HrpE VAPA_1c43270 52924ba138a80c787b21d2642b3333e8 236 PRINTS PR01003 Flagellar assembly protein FliH signature 188 204 2.5E-21 T 12-10-2018 IPR000563 Flagellar assembly protein FliH GO:0003774|GO:0009288|GO:0071973 VAPA_1c43270 52924ba138a80c787b21d2642b3333e8 236 PRINTS PR01003 Flagellar assembly protein FliH signature 160 187 2.5E-21 T 12-10-2018 IPR000563 Flagellar assembly protein FliH GO:0003774|GO:0009288|GO:0071973 VAPA_1c43270 52924ba138a80c787b21d2642b3333e8 236 PRINTS PR01003 Flagellar assembly protein FliH signature 57 79 2.5E-21 T 12-10-2018 IPR000563 Flagellar assembly protein FliH GO:0003774|GO:0009288|GO:0071973 VAPA_1c43270 52924ba138a80c787b21d2642b3333e8 236 PRINTS PR01003 Flagellar assembly protein FliH signature 119 136 2.5E-21 T 12-10-2018 IPR000563 Flagellar assembly protein FliH GO:0003774|GO:0009288|GO:0071973 VAPA_1c43270 52924ba138a80c787b21d2642b3333e8 236 PRINTS PR01003 Flagellar assembly protein FliH signature 205 230 2.5E-21 T 12-10-2018 IPR000563 Flagellar assembly protein FliH GO:0003774|GO:0009288|GO:0071973 VAPA_1c43270 52924ba138a80c787b21d2642b3333e8 236 PRINTS PR01003 Flagellar assembly protein FliH signature 137 159 2.5E-21 T 12-10-2018 IPR000563 Flagellar assembly protein FliH GO:0003774|GO:0009288|GO:0071973 VAPA_1c06270 9c04b79dd5ef223f8060d431798b93b0 343 Pfam PF06812 ImpA, N-terminal, type VI secretion system 11 134 5.1E-35 T 12-10-2018 IPR010657 ImpA, N-terminal VAPA_1c06270 9c04b79dd5ef223f8060d431798b93b0 343 TIGRFAM TIGR03363 VI_chp_8: type VI secretion-associated protein, ImpA family 7 338 5.0E-67 T 12-10-2018 IPR017740 Type VI secretion system-associated, ImpA VAPA_1c49700 67a1a3e23e18952398b835c7f7ccb06d 346 Pfam PF13515 Fusaric acid resistance protein-like 32 157 8.5E-15 T 12-10-2018 VAPA_1c01250 315d0a8874788018c4bbd20919cd5bb1 134 Pfam PF04020 Mycobacterial 4 TMS phage holin, superfamily IV 8 108 4.3E-30 T 12-10-2018 IPR007165 Mycobacterial 4 TMS phage holin, superfamily IV VAPA_1c43560 6c85365e04fc1393349a6382a41f7f31 135 Pfam PF00460 Flagella basal body rod protein 9 39 9.0E-8 T 12-10-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 VAPA_1c43560 6c85365e04fc1393349a6382a41f7f31 135 TIGRFAM TIGR01396 FlgB: flagellar basal-body rod protein FlgB 6 132 7.9E-36 T 12-10-2018 IPR006300 Flagellar basal-body rod protein FlgB GO:0030694|GO:0071973 VAPA_1c43560 6c85365e04fc1393349a6382a41f7f31 135 PIRSF PIRSF002889 1 135 8.3E-37 T 12-10-2018 IPR006300 Flagellar basal-body rod protein FlgB GO:0030694|GO:0071973 VAPA_1c38150 181d4ee76e3b8fc6986807e334a7875d 213 Pfam PF01081 KDPG and KHG aldolase 9 188 8.6E-35 T 12-10-2018 IPR000887 KDPG/KHG aldolase GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 VAPA_1c38150 181d4ee76e3b8fc6986807e334a7875d 213 Gene3D G3DSA:3.20.20.70 7 210 3.5E-61 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 VAPA_1c38150 181d4ee76e3b8fc6986807e334a7875d 213 SUPERFAMILY SSF51569 5 208 1.04E-58 T 12-10-2018 VAPA_1c00460 269e035409c0c2e8085d1b2cf97e6d21 204 PIRSF PIRSF006324 1 204 1.5E-47 T 12-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 VAPA_1c00460 269e035409c0c2e8085d1b2cf97e6d21 204 Pfam PF01810 LysE type translocator 17 203 6.1E-33 T 12-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 VAPA_1c01550 3e7b692d015e899560e0cfe31e13eb4b 300 TIGRFAM TIGR03409 urea_trans_UrtB: urea ABC transporter, permease protein UrtB 8 299 8.8E-117 T 12-10-2018 IPR017779 ABC transporter, urea permease protein UrtB, bacterial-type VAPA_1c01550 3e7b692d015e899560e0cfe31e13eb4b 300 Pfam PF02653 Branched-chain amino acid transport system / permease component 10 286 1.9E-49 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 VAPA_1c45210 2b17270b0aeeabcccd7e9df17ac10238 291 SUPERFAMILY SSF161098 82 269 1.44E-26 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c45210 2b17270b0aeeabcccd7e9df17ac10238 291 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 105 288 4.6E-31 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 VAPA_1c45210 2b17270b0aeeabcccd7e9df17ac10238 291 Gene3D G3DSA:1.10.3720.10 76 290 9.8E-24 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c03220 68c9f218482e986b6decb54da16d6e14 90 SUPERFAMILY SSF56349 2 46 4.71E-11 T 12-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 VAPA_1c03220 68c9f218482e986b6decb54da16d6e14 90 Pfam PF00589 Phage integrase family 2 34 2.9E-8 T 12-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 VAPA_1c03220 68c9f218482e986b6decb54da16d6e14 90 Gene3D G3DSA:1.10.443.10 1 51 1.1E-11 T 12-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 VAPA_1c08400 b225d06275da2af5762aa4a95397f88b 200 Pfam PF07040 Protein of unknown function (DUF1326) 11 189 3.3E-57 T 12-10-2018 IPR009758 Protein of unknown function DUF1326 VAPA_1c05540 a8df994bb711c40f916155892ca13c70 143 SUPERFAMILY SSF88723 9 128 2.61E-9 T 12-10-2018 IPR029060 PIN-like domain superfamily VAPA_1c05540 a8df994bb711c40f916155892ca13c70 143 TIGRFAM TIGR00305 TIGR00305: putative toxin-antitoxin system toxin component, PIN family 9 124 9.0E-8 T 12-10-2018 IPR002850 PIN family, putative toxin-antitoxin system toxin component VAPA_1c05540 a8df994bb711c40f916155892ca13c70 143 Pfam PF13470 PIN domain 9 121 9.4E-20 T 12-10-2018 IPR002716 PIN domain VAPA_1c08300 ea39720b8e938ef07f8ba6fad4daeaa0 334 SUPERFAMILY SSF53448 7 235 1.22E-39 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases VAPA_1c08300 ea39720b8e938ef07f8ba6fad4daeaa0 334 Pfam PF00535 Glycosyl transferase family 2 10 138 4.9E-18 T 12-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 VAPA_1c08300 ea39720b8e938ef07f8ba6fad4daeaa0 334 Gene3D G3DSA:3.90.550.10 1 261 6.2E-36 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases VAPA_1c25050 157b9c093172dfba65d3f7c97339a1fd 140 Pfam PF12279 Protein of unknown function (DUF3619) 13 134 1.5E-41 T 12-10-2018 IPR022064 Protein of unknown function DUF3619 VAPA_2c00510 ee4cdb50bd3faa2c4310f51e2c429cc6 291 Pfam PF04909 Amidohydrolase 22 291 2.0E-23 T 12-10-2018 IPR006680 Amidohydrolase-related GO:0016787 VAPA_2c00510 ee4cdb50bd3faa2c4310f51e2c429cc6 291 Gene3D G3DSA:3.20.20.140 19 291 2.5E-52 T 12-10-2018 VAPA_2c00510 ee4cdb50bd3faa2c4310f51e2c429cc6 291 SUPERFAMILY SSF51556 20 291 1.52E-39 T 12-10-2018 IPR032466 Metal-dependent hydrolase VAPA_1c09290 9763424a0d1211181629bcd02648cb48 705 Pfam PF04632 Fusaric acid resistance protein family 14 694 2.7E-179 T 12-10-2018 IPR006726 Para-hydroxybenzoic acid efflux pump subunit AaeB/fusaric acid resistance protein GO:0005886|GO:0022857|GO:0055085 VAPA_1c43680 e84f1f69322cd2e4b52d467bd8f9c874 219 Gene3D G3DSA:1.10.530.10 86 205 3.1E-21 T 12-10-2018 VAPA_1c43680 e84f1f69322cd2e4b52d467bd8f9c874 219 Pfam PF01464 Transglycosylase SLT domain 105 194 1.5E-14 T 12-10-2018 IPR008258 Transglycosylase SLT domain 1 VAPA_1c43680 e84f1f69322cd2e4b52d467bd8f9c874 219 SUPERFAMILY SSF53955 90 206 8.8E-28 T 12-10-2018 IPR023346 Lysozyme-like domain superfamily VAPA_1c06670 ed163f5c66d248a8b2dc2e50099f41cf 101 Pfam PF03992 Antibiotic biosynthesis monooxygenase 1 77 3.2E-14 T 12-10-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain VAPA_1c06670 ed163f5c66d248a8b2dc2e50099f41cf 101 Gene3D G3DSA:3.30.70.100 1 96 1.2E-34 T 12-10-2018 VAPA_1c06670 ed163f5c66d248a8b2dc2e50099f41cf 101 SUPERFAMILY SSF54909 1 94 1.79E-25 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel VAPA_2c05370 57e0887f75ddb9a2c2b8717c46c5ef10 674 Pfam PF00361 Proton-conducting membrane transporter 139 421 4.8E-52 T 12-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VAPA_2c05370 57e0887f75ddb9a2c2b8717c46c5ef10 674 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 245 269 5.6E-9 T 12-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VAPA_2c05370 57e0887f75ddb9a2c2b8717c46c5ef10 674 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 176 200 5.6E-9 T 12-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VAPA_2c05370 57e0887f75ddb9a2c2b8717c46c5ef10 674 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 145 164 5.6E-9 T 12-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VAPA_2c05370 57e0887f75ddb9a2c2b8717c46c5ef10 674 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 396 422 5.6E-9 T 12-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VAPA_1c06850 7083dcc92d262be6a9017e69cb2ec7d2 332 Pfam PF00561 alpha/beta hydrolase fold 75 195 6.6E-16 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 VAPA_1c06850 7083dcc92d262be6a9017e69cb2ec7d2 332 Gene3D G3DSA:3.40.50.1820 53 332 8.9E-41 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c06850 7083dcc92d262be6a9017e69cb2ec7d2 332 SUPERFAMILY SSF53474 38 332 7.79E-42 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c38650 cfe6ba01536d27d1693c54faf54d3e9c 450 SUPERFAMILY SSF51905 3 255 5.1E-19 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c38650 cfe6ba01536d27d1693c54faf54d3e9c 450 Gene3D G3DSA:3.50.50.60 2 425 1.3E-154 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c38650 cfe6ba01536d27d1693c54faf54d3e9c 450 Pfam PF13434 L-lysine 6-monooxygenase (NADPH-requiring) 3 347 2.4E-131 T 12-10-2018 IPR025700 L-lysine 6-monooxygenase/L-ornithine 5-monooxygenase VAPA_1c52860 57b93c571bc2cb0785f6d66c30197978 150 Gene3D G3DSA:2.40.128.270 36 147 7.8E-23 T 12-10-2018 IPR038670 HslJ-like superfamily VAPA_1c52860 57b93c571bc2cb0785f6d66c30197978 150 Pfam PF03724 META domain 36 145 1.2E-25 T 12-10-2018 IPR005184 Domain of unknown function DUF306, Meta/HslJ VAPA_1c29320 7f036349e639af0c43926dc2944f03f5 141 Pfam PF13664 Domain of unknown function (DUF4149) 8 103 1.1E-17 T 12-10-2018 IPR025423 Domain of unknown function DUF4149 VAPA_1c37820 a7ff7f459937f597028653394870235c 563 Gene3D G3DSA:3.40.50.12780 12 461 6.2E-113 T 12-10-2018 VAPA_1c37820 a7ff7f459937f597028653394870235c 563 ProSitePatterns PS00455 Putative AMP-binding domain signature. 217 228 - T 12-10-2018 IPR020845 AMP-binding, conserved site VAPA_1c37820 a7ff7f459937f597028653394870235c 563 Pfam PF00501 AMP-binding enzyme 30 465 2.8E-106 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 VAPA_1c37820 a7ff7f459937f597028653394870235c 563 Gene3D G3DSA:3.30.300.310 462 563 4.2E-27 T 12-10-2018 VAPA_1c37820 a7ff7f459937f597028653394870235c 563 Pfam PF13193 AMP-binding enzyme C-terminal domain 475 551 8.2E-19 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain VAPA_1c37820 a7ff7f459937f597028653394870235c 563 SUPERFAMILY SSF56801 10 559 6.15E-150 T 12-10-2018 VAPA_1c38610 9439e5b3787cdcff95ee9f6c9790ef76 563 SMART SM00382 367 556 1.7E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c38610 9439e5b3787cdcff95ee9f6c9790ef76 563 Pfam PF00005 ABC transporter 360 499 2.2E-22 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c38610 9439e5b3787cdcff95ee9f6c9790ef76 563 TIGRFAM TIGR01194 cyc_pep_trnsptr: cyclic peptide transporter 9 555 4.8E-189 T 12-10-2018 IPR005898 Cyclic peptide transporter GO:0005524|GO:0015833|GO:0016021|GO:1904680 VAPA_1c38610 9439e5b3787cdcff95ee9f6c9790ef76 563 Pfam PF00664 ABC transporter transmembrane region 27 169 2.1E-7 T 12-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 VAPA_1c38610 9439e5b3787cdcff95ee9f6c9790ef76 563 SUPERFAMILY SSF90123 15 313 1.96E-30 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 VAPA_1c38610 9439e5b3787cdcff95ee9f6c9790ef76 563 Gene3D G3DSA:3.40.50.300 329 560 1.1E-36 T 12-10-2018 VAPA_1c38610 9439e5b3787cdcff95ee9f6c9790ef76 563 Gene3D G3DSA:1.20.1560.10 4 315 6.7E-25 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 VAPA_1c38610 9439e5b3787cdcff95ee9f6c9790ef76 563 SUPERFAMILY SSF52540 329 552 3.84E-39 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c41560 648685157266a03258e2e3f74d1b3cde 424 SUPERFAMILY SSF103473 20 400 2.09E-56 T 12-10-2018 IPR036259 MFS transporter superfamily VAPA_1c41560 648685157266a03258e2e3f74d1b3cde 424 Gene3D G3DSA:1.20.1250.20 27 408 2.7E-41 T 12-10-2018 VAPA_1c41560 648685157266a03258e2e3f74d1b3cde 424 Pfam PF07690 Major Facilitator Superfamily 36 342 3.7E-34 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 VAPA_1c24090 9950350f419144e22f24053300cef1e8 300 SUPERFAMILY SSF51735 9 263 6.72E-53 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c24090 9950350f419144e22f24053300cef1e8 300 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 190 207 4.4E-24 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c24090 9950350f419144e22f24053300cef1e8 300 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 86 97 4.4E-24 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c24090 9950350f419144e22f24053300cef1e8 300 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 226 246 4.4E-24 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c24090 9950350f419144e22f24053300cef1e8 300 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 169 188 4.4E-24 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c24090 9950350f419144e22f24053300cef1e8 300 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 11 28 4.4E-24 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c24090 9950350f419144e22f24053300cef1e8 300 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 19 262 4.0E-34 T 12-10-2018 VAPA_1c24090 9950350f419144e22f24053300cef1e8 300 Gene3D G3DSA:3.40.50.720 1 295 9.0E-61 T 12-10-2018 VAPA_1c23930 5951db59ee017f8066415a29f688a57e 202 Pfam PF02417 Chromate transporter 15 197 4.2E-28 T 12-10-2018 IPR003370 Chromate transporter GO:0015109|GO:0015703 VAPA_1c23310 63c7bc0b9455fd452525c22ed02f72f4 98 Pfam PF05957 Bacterial protein of unknown function (DUF883) 7 98 2.6E-20 T 12-10-2018 IPR010279 Inner membrane protein YqjD/ElaB GO:0043022 VAPA_1c06900 efbc518c63f7092c9949b5d94ec19b4a 305 Pfam PF02653 Branched-chain amino acid transport system / permease component 10 293 1.7E-37 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 VAPA_1c29970 47adbdac3ae3fea970a4c3d53c6e9fa1 341 SUPERFAMILY SSF53383 20 330 1.16E-45 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase VAPA_1c29970 47adbdac3ae3fea970a4c3d53c6e9fa1 341 Gene3D G3DSA:3.90.1150.10 24 331 5.0E-48 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 VAPA_1c29970 47adbdac3ae3fea970a4c3d53c6e9fa1 341 Gene3D G3DSA:3.40.640.10 35 242 5.0E-48 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 VAPA_1c29970 47adbdac3ae3fea970a4c3d53c6e9fa1 341 Pfam PF00155 Aminotransferase class I and II 160 331 4.3E-11 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 VAPA_1c35690 f4b2eb11b730e59bcaf23edf1052ce1d 169 SUPERFAMILY SSF52540 42 129 1.18E-16 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c35690 f4b2eb11b730e59bcaf23edf1052ce1d 169 Pfam PF02367 Threonylcarbamoyl adenosine biosynthesis protein TsaE 22 149 2.1E-34 T 12-10-2018 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 VAPA_1c35690 f4b2eb11b730e59bcaf23edf1052ce1d 169 TIGRFAM TIGR00150 T6A_YjeE: tRNA threonylcarbamoyl adenosine modification protein YjeE 23 155 4.0E-33 T 12-10-2018 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 VAPA_1c35690 f4b2eb11b730e59bcaf23edf1052ce1d 169 Gene3D G3DSA:3.40.50.300 17 168 3.2E-37 T 12-10-2018 VAPA_1c08010 06bdeff55f4ae807ec5c5b117333abc7 210 PIRSF PIRSF006324 1 209 2.2E-46 T 12-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 VAPA_1c08010 06bdeff55f4ae807ec5c5b117333abc7 210 Pfam PF01810 LysE type translocator 16 206 7.4E-31 T 12-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 VAPA_1c36080 fd02c839cc0a6264bc6f302fa54e0b30 102 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 9 97 5.0E-22 T 12-10-2018 IPR039428 NADH-ubiquinone oxidoreductase chain 4L/Mnh complex subunit C1-like VAPA_1c36080 fd02c839cc0a6264bc6f302fa54e0b30 102 Hamap MF_01456 NAD(P)H-quinone oxidoreductase subunit 4L, chloroplastic [ndhE]. 1 102 20.247 T 12-10-2018 IPR001133 NADH-ubiquinone oxidoreductase chain 4L/K GO:0016651|GO:0042773|GO:0055114 VAPA_1c10450 7b2f2c642a58744e846bce0e48ed630e 190 PRINTS PR01837 MgtC/SapB protein signature 53 71 6.8E-39 T 12-10-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 VAPA_1c10450 7b2f2c642a58744e846bce0e48ed630e 190 PRINTS PR01837 MgtC/SapB protein signature 110 134 6.8E-39 T 12-10-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 VAPA_1c10450 7b2f2c642a58744e846bce0e48ed630e 190 PRINTS PR01837 MgtC/SapB protein signature 80 102 6.8E-39 T 12-10-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 VAPA_1c10450 7b2f2c642a58744e846bce0e48ed630e 190 PRINTS PR01837 MgtC/SapB protein signature 34 53 6.8E-39 T 12-10-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 VAPA_1c10450 7b2f2c642a58744e846bce0e48ed630e 190 Pfam PF02308 MgtC family 31 154 2.1E-37 T 12-10-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 VAPA_2c00780 053bba1a9bcac31af425fd8dd26a88a9 132 SUPERFAMILY SSF54427 1 127 2.93E-19 T 12-10-2018 IPR032710 NTF2-like domain superfamily VAPA_2c00780 053bba1a9bcac31af425fd8dd26a88a9 132 Gene3D G3DSA:3.10.450.50 4 128 1.5E-21 T 12-10-2018 VAPA_2c00780 053bba1a9bcac31af425fd8dd26a88a9 132 Pfam PF12680 SnoaL-like domain 14 115 4.3E-13 T 12-10-2018 IPR037401 SnoaL-like domain VAPA_1c18260 e535c26d5ac966102fd1830350f8c0bc 378 Pfam PF12698 ABC-2 family transporter protein 27 369 3.3E-51 T 12-10-2018 VAPA_1c53550 af4beae98691438c191a4746d0a49b82 285 Gene3D G3DSA:1.10.620.20 8 228 1.1E-12 T 12-10-2018 IPR012348 Ribonucleotide reductase-like GO:0016491|GO:0055114 Reactome: R-HSA-499943 VAPA_1c53550 af4beae98691438c191a4746d0a49b82 285 SUPERFAMILY SSF47240 6 272 1.31E-46 T 12-10-2018 IPR009078 Ferritin-like superfamily VAPA_1c35040 ee70c917843384ee44758df0b04a13f2 152 Pfam PF14588 YjgF/chorismate_mutase-like, putative endoribonuclease 6 151 6.5E-25 T 12-10-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like VAPA_1c35040 ee70c917843384ee44758df0b04a13f2 152 Gene3D G3DSA:3.30.1330.40 1 151 6.4E-56 T 12-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 VAPA_1c35040 ee70c917843384ee44758df0b04a13f2 152 SUPERFAMILY SSF55298 1 151 2.04E-50 T 12-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 VAPA_1c17760 8e568eb18ad285950e9838da1c430105 206 Pfam PF13761 Domain of unknown function (DUF4166) 20 201 4.7E-35 T 12-10-2018 IPR025311 Domain of unknown function DUF4166 VAPA_1c30240 0bf05df5ca0cf7dd841a8a3ef0acd994 84 TIGRFAM TIGR04438 small_Trp_rich: small Trp-rich protein 1 74 2.9E-36 T 12-10-2018 IPR031044 Small Trp-rich protein VAPA_1c38630 7e8f21774eb13f1189e997808c8ff011 281 Gene3D G3DSA:3.40.50.170 101 278 5.0E-14 T 12-10-2018 VAPA_1c38630 7e8f21774eb13f1189e997808c8ff011 281 Pfam PF00551 Formyl transferase 121 261 9.7E-7 T 12-10-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 VAPA_1c38630 7e8f21774eb13f1189e997808c8ff011 281 SUPERFAMILY SSF53328 114 275 8.14E-15 T 12-10-2018 IPR036477 Formyl transferase, N-terminal domain superfamily GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 VAPA_1c25010 155578d5a461d1cdce5e2d9e54e455cc 196 Pfam PF03641 Possible lysine decarboxylase 49 178 1.3E-41 T 12-10-2018 IPR031100 LOG family VAPA_1c25010 155578d5a461d1cdce5e2d9e54e455cc 196 TIGRFAM TIGR00730 TIGR00730: TIGR00730 family protein 6 180 2.3E-61 T 12-10-2018 IPR005269 Cytokinin riboside 5'-monophosphate phosphoribohydrolase LOG VAPA_1c25010 155578d5a461d1cdce5e2d9e54e455cc 196 SUPERFAMILY SSF102405 4 179 3.05E-61 T 12-10-2018 VAPA_1c25010 155578d5a461d1cdce5e2d9e54e455cc 196 Gene3D G3DSA:3.40.50.450 6 189 4.5E-71 T 12-10-2018 VAPA_1c03100 5f3ce55b61239d2e4401ec9aa33a5dc4 333 Pfam PF04381 Putative exonuclease, RdgC 4 297 4.7E-107 T 12-10-2018 IPR007476 Putative exonuclease, RdgC GO:0006310 VAPA_1c32110 704c55ad43f37f8aa262e45fd653551d 339 PIRSF PIRSF017082 9 339 2.7E-85 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c32110 704c55ad43f37f8aa262e45fd653551d 339 Gene3D G3DSA:3.40.190.10 144 266 2.2E-112 T 12-10-2018 VAPA_1c32110 704c55ad43f37f8aa262e45fd653551d 339 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 65 335 1.4E-92 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c32110 704c55ad43f37f8aa262e45fd653551d 339 SUPERFAMILY SSF53850 133 293 5.1E-11 T 12-10-2018 VAPA_1c32110 704c55ad43f37f8aa262e45fd653551d 339 Gene3D G3DSA:3.40.190.150 46 328 2.2E-112 T 12-10-2018 VAPA_2c11060 8b94841cc99ab9655ed35ad940725fc2 290 SUPERFAMILY SSF56281 8 288 2.3E-49 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like VAPA_2c11060 8b94841cc99ab9655ed35ad940725fc2 290 SMART SM00849 14 208 1.4E-25 T 12-10-2018 IPR001279 Metallo-beta-lactamase VAPA_2c11060 8b94841cc99ab9655ed35ad940725fc2 290 Gene3D G3DSA:3.60.15.10 2 290 7.8E-101 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like VAPA_2c11060 8b94841cc99ab9655ed35ad940725fc2 290 Pfam PF00753 Metallo-beta-lactamase superfamily 14 208 1.2E-18 T 12-10-2018 IPR001279 Metallo-beta-lactamase VAPA_2c05010 bbdfad5b9c3594d81b35af3b184338d9 135 Pfam PF03466 LysR substrate binding domain 8 121 4.9E-9 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_2c05010 bbdfad5b9c3594d81b35af3b184338d9 135 SUPERFAMILY SSF53850 7 121 1.14E-7 T 12-10-2018 VAPA_2c05010 bbdfad5b9c3594d81b35af3b184338d9 135 Gene3D G3DSA:3.40.190.10 11 108 9.0E-7 T 12-10-2018 VAPA_1c29090 a71daf2fd94ab73691a4840eecd59886 210 Pfam PF01618 MotA/TolQ/ExbB proton channel family 67 195 5.2E-32 T 12-10-2018 IPR002898 MotA/TolQ/ExbB proton channel VAPA_2c12840 f38eac7411e682b36503c99e9b11ee8c 89 Gene3D G3DSA:1.10.260.40 3 75 2.2E-12 T 12-10-2018 VAPA_2c12840 f38eac7411e682b36503c99e9b11ee8c 89 SMART SM00530 14 68 2.1E-5 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 VAPA_2c12840 f38eac7411e682b36503c99e9b11ee8c 89 SUPERFAMILY SSF47413 3 69 9.92E-11 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 VAPA_2c12840 f38eac7411e682b36503c99e9b11ee8c 89 Pfam PF01381 Helix-turn-helix 16 65 1.9E-7 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 VAPA_1c40890 dc7347500b6bf5de2367a0cd3fdb6643 360 Pfam PF01594 AI-2E family transporter 14 339 1.8E-50 T 12-10-2018 IPR002549 Transmembrane protein TqsA-like VAPA_1c32750 7e29deb03ea66aa3efdb93a416cca284 151 SUPERFAMILY SSF46689 4 126 2.69E-8 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 VAPA_1c45710 2d907ce9b557ee0e529057e2c356395f 206 Gene3D G3DSA:3.40.50.300 1 200 2.2E-33 T 12-10-2018 VAPA_1c45710 2d907ce9b557ee0e529057e2c356395f 206 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 4 181 2.4E-15 T 12-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain VAPA_1c45710 2d907ce9b557ee0e529057e2c356395f 206 SUPERFAMILY SSF52540 1 193 6.55E-31 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c45710 2d907ce9b557ee0e529057e2c356395f 206 PIRSF PIRSF009320 1 202 4.2E-26 T 12-10-2018 VAPA_2c12900 83fcd65370ff026af19312b9466d5324 174 Pfam PF13683 Integrase core domain 102 147 6.0E-9 T 12-10-2018 IPR001584 Integrase, catalytic core GO:0015074 VAPA_1c06330 d4167d1c7d0331f91a4ccb05ca9b4327 91 TIGRFAM TIGR04042 MSMEG_0570_fam: MSMEG_0570 family protein 1 87 2.1E-40 T 12-10-2018 IPR023846 Conserved hypothetical protein CHP04042, MSMEG0570 VAPA_2c09700 392ec667919fd75d5245bbd9d0d268b3 156 Pfam PF12802 MarR family 40 88 1.2E-7 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 VAPA_2c09700 392ec667919fd75d5245bbd9d0d268b3 156 SUPERFAMILY SSF46785 8 142 3.39E-21 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_2c09700 392ec667919fd75d5245bbd9d0d268b3 156 SMART SM00347 31 128 1.9E-4 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 VAPA_2c09700 392ec667919fd75d5245bbd9d0d268b3 156 Gene3D G3DSA:1.10.10.10 5 143 4.0E-22 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c36180 0d7911b1a0ffb03e7f85e100a6886615 119 Pfam PF00507 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 25 118 1.3E-40 T 12-10-2018 IPR000440 NADH:ubiquinone/plastoquinone oxidoreductase, chain 3 GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VAPA_1c36180 0d7911b1a0ffb03e7f85e100a6886615 119 Hamap MF_01394 NAD(P)H-quinone oxidoreductase subunit 3, chloroplastic [ndhC]. 2 119 20.411 T 12-10-2018 IPR023043 NAD(P)H-quinone oxidoreductase subunit 3, bacterial/plastid GO:0016651|GO:0055114 VAPA_1c36180 0d7911b1a0ffb03e7f85e100a6886615 119 Gene3D G3DSA:1.20.58.1610 1 119 9.2E-46 T 12-10-2018 IPR038430 NADH:ubiquinone oxidoreductase, subunit 3 superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VAPA_2c11680 c0067ad3d7065f8304995438af62192f 150 Pfam PF01609 Transposase DDE domain 7 69 7.5E-9 T 12-10-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 VAPA_2c11680 c0067ad3d7065f8304995438af62192f 150 SUPERFAMILY SSF53098 10 76 1.21E-11 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily VAPA_1c54590 86ce584f0d456d26da4e6a1f892e130f 140 Gene3D G3DSA:3.10.180.10 1 140 1.3E-57 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase VAPA_1c54590 86ce584f0d456d26da4e6a1f892e130f 140 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 8 126 3.4E-4 T 12-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain VAPA_1c54590 86ce584f0d456d26da4e6a1f892e130f 140 SUPERFAMILY SSF54593 7 132 1.48E-24 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase VAPA_1c31830 0d985201bd211893db0ca7cf7a597c94 240 TIGRFAM TIGR02796 tolQ: protein TolQ 6 220 1.1E-84 T 12-10-2018 IPR014163 Tol-Pal system, TolQ GO:0016021|GO:0043213 VAPA_1c31830 0d985201bd211893db0ca7cf7a597c94 240 Hamap MF_02202 Tol-Pal system protein TolQ [tolQ]. 5 225 40.894 T 12-10-2018 IPR014163 Tol-Pal system, TolQ GO:0016021|GO:0043213 VAPA_1c31830 0d985201bd211893db0ca7cf7a597c94 240 Pfam PF01618 MotA/TolQ/ExbB proton channel family 79 208 3.8E-41 T 12-10-2018 IPR002898 MotA/TolQ/ExbB proton channel VAPA_1c55010 383d37c92a7c8dfe10fb819bbff3d1b0 181 Pfam PF00076 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 5 74 9.2E-23 T 12-10-2018 IPR000504 RNA recognition motif domain GO:0003676 VAPA_1c55010 383d37c92a7c8dfe10fb819bbff3d1b0 181 SUPERFAMILY SSF54928 3 110 4.7E-31 T 12-10-2018 IPR035979 RNA-binding domain superfamily GO:0003676 VAPA_1c55010 383d37c92a7c8dfe10fb819bbff3d1b0 181 Gene3D G3DSA:3.30.70.330 1 102 3.1E-31 T 12-10-2018 IPR012677 Nucleotide-binding alpha-beta plait domain superfamily VAPA_1c55010 383d37c92a7c8dfe10fb819bbff3d1b0 181 SMART SM00360 4 77 3.1E-30 T 12-10-2018 IPR000504 RNA recognition motif domain GO:0003676 VAPA_1c10350 945a84016c021acd2df189bfcb75ac09 64 Pfam PF11146 Protein of unknown function (DUF2905) 3 64 2.4E-18 T 12-10-2018 IPR021320 Protein of unknown function DUF2905 VAPA_2c01270 2e32b664e16e8a2601ca388e06d5914e 84 Pfam PF11903 ParD-like antitoxin of type II bacterial toxin-antitoxin system 1 63 1.5E-28 T 12-10-2018 IPR021831 ParD-like antitoxin of type II bacterial toxin-antitoxin system VAPA_1c40700 574196dce3045ec5fe3d379c75b00ca8 327 PIRSF PIRSF017082 1 327 2.4E-117 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c40700 574196dce3045ec5fe3d379c75b00ca8 327 Gene3D G3DSA:3.40.190.10 131 253 7.6E-93 T 12-10-2018 VAPA_1c40700 574196dce3045ec5fe3d379c75b00ca8 327 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 56 320 1.7E-62 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c40700 574196dce3045ec5fe3d379c75b00ca8 327 Gene3D G3DSA:3.40.190.150 35 290 7.6E-93 T 12-10-2018 VAPA_1c40700 574196dce3045ec5fe3d379c75b00ca8 327 SUPERFAMILY SSF53850 123 291 4.61E-12 T 12-10-2018 VAPA_1c08310 d9a0c46cac3acf2fdc826945c9738ac8 354 SUPERFAMILY SSF53448 15 267 1.04E-53 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases VAPA_1c08310 d9a0c46cac3acf2fdc826945c9738ac8 354 Pfam PF00535 Glycosyl transferase family 2 24 187 1.0E-25 T 12-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 VAPA_1c08310 d9a0c46cac3acf2fdc826945c9738ac8 354 Gene3D G3DSA:3.90.550.10 8 262 1.5E-54 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases VAPA_1c16960 74f2790af57973b7164943518b6fc45a 92 PIRSF PIRSF028784 1 92 4.0E-26 T 12-10-2018 IPR007208 Na(+)/H(+) antiporter subunit F-like GO:0015075|GO:0016021|GO:0034220 VAPA_1c16960 74f2790af57973b7164943518b6fc45a 92 Pfam PF04066 Multiple resistance and pH regulation protein F (MrpF / PhaF) 34 85 4.8E-18 T 12-10-2018 IPR007208 Na(+)/H(+) antiporter subunit F-like GO:0015075|GO:0016021|GO:0034220 VAPA_1c13930 8b2726e48180cba4da4f7fd1151368bd 355 Gene3D G3DSA:3.40.50.1580 77 332 1.0E-14 T 12-10-2018 VAPA_1c13930 8b2726e48180cba4da4f7fd1151368bd 355 PIRSF PIRSF013171 10 355 9.8E-65 T 12-10-2018 IPR009486 Purine nucleoside permease GO:0055085 VAPA_1c13930 8b2726e48180cba4da4f7fd1151368bd 355 Pfam PF06516 Purine nucleoside permease (NUP) 50 353 6.2E-79 T 12-10-2018 IPR009486 Purine nucleoside permease GO:0055085 VAPA_1c13930 8b2726e48180cba4da4f7fd1151368bd 355 SUPERFAMILY SSF53167 104 280 5.93E-8 T 12-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 VAPA_1c32280 efc92f4fcac88d00ace57e1e98249adb 233 TIGRFAM TIGR03410 urea_trans_UrtE: urea ABC transporter, ATP-binding protein UrtE 7 233 4.3E-100 T 12-10-2018 IPR017780 ABC transporter, urea, ATP-binding protein, UrtE VAPA_1c32280 efc92f4fcac88d00ace57e1e98249adb 233 SUPERFAMILY SSF52540 2 220 6.86E-58 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c32280 efc92f4fcac88d00ace57e1e98249adb 233 SMART SM00382 30 212 3.7E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c32280 efc92f4fcac88d00ace57e1e98249adb 233 Gene3D G3DSA:3.40.50.300 3 230 1.1E-59 T 12-10-2018 VAPA_1c32280 efc92f4fcac88d00ace57e1e98249adb 233 Pfam PF00005 ABC transporter 21 162 1.0E-31 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c17370 e4b7a0f6601c8c741b9caac9690849ba 266 Pfam PF00994 Probable molybdopterin binding domain 7 172 8.3E-26 T 12-10-2018 IPR001453 MoaB/Mog domain VAPA_1c17370 e4b7a0f6601c8c741b9caac9690849ba 266 SUPERFAMILY SSF53218 5 209 9.16E-32 T 12-10-2018 IPR036425 MoaB/Mog-like domain superfamily VAPA_1c17370 e4b7a0f6601c8c741b9caac9690849ba 266 Gene3D G3DSA:3.40.980.10 3 175 1.3E-40 T 12-10-2018 IPR036425 MoaB/Mog-like domain superfamily VAPA_1c17370 e4b7a0f6601c8c741b9caac9690849ba 266 SMART SM00852 6 179 1.3E-29 T 12-10-2018 IPR001453 MoaB/Mog domain VAPA_1c32650 d3be79b0d21a9bcba2d303924f4cc669 519 SUPERFAMILY SSF51905 6 273 1.55E-12 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c32650 d3be79b0d21a9bcba2d303924f4cc669 519 Gene3D G3DSA:3.50.50.60 393 504 9.5E-28 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c32650 d3be79b0d21a9bcba2d303924f4cc669 519 Gene3D G3DSA:3.50.50.60 1 117 1.5E-26 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c32650 d3be79b0d21a9bcba2d303924f4cc669 519 Gene3D G3DSA:3.50.50.60 135 346 2.1E-39 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily VAPA_1c32650 d3be79b0d21a9bcba2d303924f4cc669 519 Pfam PF06100 MCRA family 2 488 1.7E-199 T 12-10-2018 IPR010354 Oleate hydratase GO:0006631|GO:0050151|GO:0071949 VAPA_2c03130 e027e82a98fbad8d73a85a59622d3dbf 337 Gene3D G3DSA:3.40.190.10 139 262 1.5E-116 T 12-10-2018 VAPA_2c03130 e027e82a98fbad8d73a85a59622d3dbf 337 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 60 333 2.0E-92 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_2c03130 e027e82a98fbad8d73a85a59622d3dbf 337 Gene3D G3DSA:3.40.190.150 41 327 1.5E-116 T 12-10-2018 VAPA_2c03130 e027e82a98fbad8d73a85a59622d3dbf 337 PIRSF PIRSF017082 7 336 1.5E-87 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_2c03130 e027e82a98fbad8d73a85a59622d3dbf 337 SUPERFAMILY SSF53850 124 298 2.29E-17 T 12-10-2018 VAPA_1c19520 7c435cc519de77631479ff92030f8e22 476 Gene3D G3DSA:3.20.20.120 177 383 1.4E-16 T 12-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily VAPA_1c19520 7c435cc519de77631479ff92030f8e22 476 SUPERFAMILY SSF51604 208 418 7.28E-12 T 12-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily VAPA_1c19520 7c435cc519de77631479ff92030f8e22 476 Pfam PF13378 Enolase C-terminal domain-like 219 364 7.2E-8 T 12-10-2018 IPR029065 Enolase C-terminal domain-like VAPA_1c48000 da97cddc8ee5cf2ed4a3b9acbef351d2 317 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 23 317 1.1E-65 T 12-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 VAPA_1c48000 da97cddc8ee5cf2ed4a3b9acbef351d2 317 Gene3D G3DSA:1.20.1510.10 22 239 2.1E-29 T 12-10-2018 IPR027469 Cation efflux transmembrane domain superfamily VAPA_1c48000 da97cddc8ee5cf2ed4a3b9acbef351d2 317 SUPERFAMILY SSF161111 21 240 1.28E-49 T 12-10-2018 IPR027469 Cation efflux transmembrane domain superfamily VAPA_1c48000 da97cddc8ee5cf2ed4a3b9acbef351d2 317 Pfam PF01545 Cation efflux family 27 239 1.6E-39 T 12-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 VAPA_1c47200 a04c6fb16dc3cb967cb1a062d4456d3c 68 SUPERFAMILY SSF51182 6 63 1.57E-7 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily VAPA_1c47200 a04c6fb16dc3cb967cb1a062d4456d3c 68 Gene3D G3DSA:2.60.120.10 4 67 4.7E-6 T 12-10-2018 IPR014710 RmlC-like jelly roll fold VAPA_1c51920 3d16076801bceb31208ac8aafa2bbe5e 254 Pfam PF00106 short chain dehydrogenase 7 201 2.4E-30 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c51920 3d16076801bceb31208ac8aafa2bbe5e 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 5.6E-19 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c51920 3d16076801bceb31208ac8aafa2bbe5e 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 5.6E-19 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c51920 3d16076801bceb31208ac8aafa2bbe5e 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 5.6E-19 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c51920 3d16076801bceb31208ac8aafa2bbe5e 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 5.6E-19 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c51920 3d16076801bceb31208ac8aafa2bbe5e 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 180 197 5.6E-19 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c51920 3d16076801bceb31208ac8aafa2bbe5e 254 Gene3D G3DSA:3.40.50.720 4 252 1.0E-45 T 12-10-2018 VAPA_1c51920 3d16076801bceb31208ac8aafa2bbe5e 254 SUPERFAMILY SSF51735 7 241 3.8E-39 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c51920 3d16076801bceb31208ac8aafa2bbe5e 254 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 144 172 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 VAPA_1c49510 fef4807fe35c7704a6f1707083d4e1a3 92 Pfam PF12091 Protein of unknown function (DUF3567) 1 92 7.6E-37 T 12-10-2018 IPR021951 Protein of unknown function DUF3567 VAPA_1c14620 db06012429ab4c695dcfc425365e9f9f 412 Pfam PF07690 Major Facilitator Superfamily 34 343 5.8E-34 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 VAPA_1c14620 db06012429ab4c695dcfc425365e9f9f 412 Gene3D G3DSA:1.20.1250.20 19 397 8.3E-42 T 12-10-2018 VAPA_1c14620 db06012429ab4c695dcfc425365e9f9f 412 SUPERFAMILY SSF103473 2 400 1.44E-55 T 12-10-2018 IPR036259 MFS transporter superfamily VAPA_2c02070 fd85f2d46567402f46b13d2ace1e94c3 512 SUPERFAMILY SSF53098 340 503 4.17E-30 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily VAPA_2c02070 fd85f2d46567402f46b13d2ace1e94c3 512 SUPERFAMILY SSF46689 114 212 3.23E-11 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 VAPA_2c02070 fd85f2d46567402f46b13d2ace1e94c3 512 Gene3D G3DSA:3.30.420.10 337 503 1.5E-6 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 VAPA_2c02070 fd85f2d46567402f46b13d2ace1e94c3 512 Pfam PF13276 HTH-like domain 269 322 1.1E-16 T 12-10-2018 IPR025948 HTH-like domain VAPA_2c02070 fd85f2d46567402f46b13d2ace1e94c3 512 SUPERFAMILY SSF48295 55 101 1.78E-5 T 12-10-2018 IPR010921 Trp repressor/replication initiator GO:0043565 VAPA_2c02070 fd85f2d46567402f46b13d2ace1e94c3 512 Pfam PF00665 Integrase core domain 348 461 3.1E-19 T 12-10-2018 IPR001584 Integrase, catalytic core GO:0015074 VAPA_2c02070 fd85f2d46567402f46b13d2ace1e94c3 512 Gene3D G3DSA:1.10.10.60 126 201 6.9E-5 T 12-10-2018 VAPA_1c33460 42a355ccffdabf1a4c6a09ff9121df31 230 Pfam PF11828 Protein of unknown function (DUF3348) 1 222 1.0E-78 T 12-10-2018 IPR021783 Protein of unknown function DUF3348 VAPA_1c35910 c7aaa3b901fbc085b88d7ab100f3c8c7 328 Pfam PF02653 Branched-chain amino acid transport system / permease component 29 303 1.3E-33 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 VAPA_1c28870 eb7ab93bd7cec9a9b51f262b5a136348 315 Pfam PF01048 Phosphorylase superfamily 43 312 9.9E-50 T 12-10-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 VAPA_1c28870 eb7ab93bd7cec9a9b51f262b5a136348 315 SUPERFAMILY SSF53167 37 314 1.85E-41 T 12-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 VAPA_1c28870 eb7ab93bd7cec9a9b51f262b5a136348 315 Gene3D G3DSA:3.40.50.1580 41 313 4.3E-58 T 12-10-2018 VAPA_1c12510 8219a5a028f3bd5b8a1f62da8ad1b2ed 237 Pfam PF02397 Bacterial sugar transferase 40 230 2.0E-59 T 12-10-2018 IPR003362 Bacterial sugar transferase VAPA_1c35220 ad408f6bf0bbf806d23f786875f69daa 247 Gene3D G3DSA:3.20.20.150 2 247 2.3E-60 T 12-10-2018 VAPA_1c35220 ad408f6bf0bbf806d23f786875f69daa 247 SUPERFAMILY SSF51658 4 243 1.52E-52 T 12-10-2018 IPR036237 Xylose isomerase-like superfamily VAPA_1c33430 eac55cdb01045339dc39e4b4094e13c7 213 Pfam PF11445 Protein of unknown function (DUF2894) 7 187 4.9E-66 T 12-10-2018 IPR021549 Protein of unknown function DUF2894 VAPA_1c00340 ad85e5271bcf9d35e83e316fbffae0c5 98 SUPERFAMILY SSF47336 7 86 1.57E-13 T 12-10-2018 IPR036736 ACP-like superfamily VAPA_1c00340 ad85e5271bcf9d35e83e316fbffae0c5 98 Gene3D G3DSA:1.10.1200.10 3 91 8.6E-15 T 12-10-2018 IPR036736 ACP-like superfamily VAPA_1c00340 ad85e5271bcf9d35e83e316fbffae0c5 98 Pfam PF00550 Phosphopantetheine attachment site 15 82 3.4E-11 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain VAPA_1c28670 1223fe8c3aed70677adae3389cd93fa2 258 SUPERFAMILY SSF53448 10 245 5.0E-31 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases VAPA_1c28670 1223fe8c3aed70677adae3389cd93fa2 258 Pfam PF00535 Glycosyl transferase family 2 10 139 5.5E-21 T 12-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 VAPA_1c28670 1223fe8c3aed70677adae3389cd93fa2 258 Gene3D G3DSA:3.90.550.10 4 236 1.0E-25 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases VAPA_1c19610 8b63fbf92d5bd0528cff0d6eac0ce769 147 SUPERFAMILY SSF47592 68 146 1.16E-25 T 12-10-2018 IPR036885 SWIB/MDM2 domain superfamily VAPA_1c19610 8b63fbf92d5bd0528cff0d6eac0ce769 147 Gene3D G3DSA:1.10.245.10 67 147 6.5E-26 T 12-10-2018 IPR036885 SWIB/MDM2 domain superfamily VAPA_1c19610 8b63fbf92d5bd0528cff0d6eac0ce769 147 SMART SM00151 72 147 1.4E-26 T 12-10-2018 IPR019835 SWIB domain Reactome: R-HSA-3214858|Reactome: R-HSA-8939243 VAPA_1c19610 8b63fbf92d5bd0528cff0d6eac0ce769 147 Pfam PF02201 SWIB/MDM2 domain 75 146 1.6E-26 T 12-10-2018 IPR003121 SWIB/MDM2 domain GO:0005515 VAPA_1c51820 b7202206cc6cdc18a592c65bc2a7ecd2 196 Hamap MF_00276 Potassium-transporting ATPase KdpC subunit [kdpC]. 5 192 35.175 T 12-10-2018 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 VAPA_1c51820 b7202206cc6cdc18a592c65bc2a7ecd2 196 TIGRFAM TIGR00681 kdpC: K+-transporting ATPase, C subunit 8 191 1.9E-70 T 12-10-2018 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 VAPA_1c51820 b7202206cc6cdc18a592c65bc2a7ecd2 196 Pfam PF02669 K+-transporting ATPase, c chain 9 190 5.6E-74 T 12-10-2018 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 VAPA_1c51820 b7202206cc6cdc18a592c65bc2a7ecd2 196 PIRSF PIRSF001296 4 195 6.9E-75 T 12-10-2018 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 VAPA_2c03380 b449eb9734dcba94e2f94a2f0f1557ca 175 Gene3D G3DSA:3.40.50.360 1 151 5.8E-19 T 12-10-2018 IPR029039 Flavoprotein-like superfamily VAPA_2c03380 b449eb9734dcba94e2f94a2f0f1557ca 175 SUPERFAMILY SSF52218 1 119 1.95E-12 T 12-10-2018 IPR029039 Flavoprotein-like superfamily VAPA_1c15480 80d418a236f967ffaf9db3dc2469d266 517 TIGRFAM TIGR01695 murJ_mviN: murein biosynthesis integral membrane protein MurJ 2 510 5.9E-127 T 12-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ VAPA_1c15480 80d418a236f967ffaf9db3dc2469d266 517 PIRSF PIRSF002869 1 517 2.2E-140 T 12-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ VAPA_1c15480 80d418a236f967ffaf9db3dc2469d266 517 PRINTS PR01806 Virulence factor MviN signature 33 52 2.7E-65 T 12-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ VAPA_1c15480 80d418a236f967ffaf9db3dc2469d266 517 PRINTS PR01806 Virulence factor MviN signature 153 174 2.7E-65 T 12-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ VAPA_1c15480 80d418a236f967ffaf9db3dc2469d266 517 PRINTS PR01806 Virulence factor MviN signature 129 153 2.7E-65 T 12-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ VAPA_1c15480 80d418a236f967ffaf9db3dc2469d266 517 PRINTS PR01806 Virulence factor MviN signature 364 383 2.7E-65 T 12-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ VAPA_1c15480 80d418a236f967ffaf9db3dc2469d266 517 PRINTS PR01806 Virulence factor MviN signature 416 433 2.7E-65 T 12-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ VAPA_1c15480 80d418a236f967ffaf9db3dc2469d266 517 PRINTS PR01806 Virulence factor MviN signature 266 292 2.7E-65 T 12-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ VAPA_1c15480 80d418a236f967ffaf9db3dc2469d266 517 PRINTS PR01806 Virulence factor MviN signature 52 68 2.7E-65 T 12-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ VAPA_1c15480 80d418a236f967ffaf9db3dc2469d266 517 Hamap MF_02078 Probable lipid II flippase MurJ [murJ]. 3 474 18.93 T 12-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ VAPA_1c15480 80d418a236f967ffaf9db3dc2469d266 517 Pfam PF03023 MviN-like protein 28 472 2.5E-119 T 12-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ VAPA_1c02950 d4bcf3936a632e85dec706f8db883eb7 134 Gene3D G3DSA:3.30.429.10 1 134 2.9E-51 T 12-10-2018 IPR014347 Tautomerase/MIF superfamily VAPA_1c02950 d4bcf3936a632e85dec706f8db883eb7 134 Pfam PF02962 5-carboxymethyl-2-hydroxymuconate isomerase 2 116 2.0E-17 T 12-10-2018 IPR004220 5-carboxymethyl-2-hydroxymuconate isomerase GO:0008704|GO:0019439 KEGG: 00350+5.3.3.10 VAPA_1c02950 d4bcf3936a632e85dec706f8db883eb7 134 SUPERFAMILY SSF55331 2 129 8.33E-29 T 12-10-2018 IPR014347 Tautomerase/MIF superfamily VAPA_2c11950 6b36d8c33c1a65e55e25e98cada971d2 166 Pfam PF11008 Protein of unknown function (DUF2846) 20 118 2.1E-16 T 12-10-2018 IPR022548 Domain of unknown function DUF2846 VAPA_2c02470 6cd4e8f6e7fedc838fad91fe4bb8bead 247 Pfam PF13460 NAD(P)H-binding 9 138 5.3E-12 T 12-10-2018 IPR016040 NAD(P)-binding domain VAPA_2c02470 6cd4e8f6e7fedc838fad91fe4bb8bead 247 Gene3D G3DSA:3.40.50.720 2 247 3.3E-31 T 12-10-2018 VAPA_2c02470 6cd4e8f6e7fedc838fad91fe4bb8bead 247 SUPERFAMILY SSF51735 4 246 1.2E-30 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c14730 6d790ca37c0459c24bd7cd5a0588a524 223 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 91 190 1.3E-10 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 VAPA_1c14730 6d790ca37c0459c24bd7cd5a0588a524 223 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 58 184 1.0E-10 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 VAPA_1c14730 6d790ca37c0459c24bd7cd5a0588a524 223 Pfam PF13419 Haloacid dehalogenase-like hydrolase 13 190 2.3E-33 T 12-10-2018 VAPA_1c14730 6d790ca37c0459c24bd7cd5a0588a524 223 Gene3D G3DSA:1.10.150.240 25 90 7.3E-51 T 12-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 VAPA_1c14730 6d790ca37c0459c24bd7cd5a0588a524 223 Gene3D G3DSA:3.40.50.1000 13 210 7.3E-51 T 12-10-2018 IPR023214 HAD superfamily VAPA_1c14730 6d790ca37c0459c24bd7cd5a0588a524 223 SUPERFAMILY SSF56784 10 219 1.29E-55 T 12-10-2018 IPR036412 HAD-like superfamily VAPA_1c14730 6d790ca37c0459c24bd7cd5a0588a524 223 TIGRFAM TIGR01662 HAD-SF-IIIA: HAD hydrolase, family IIIA 84 190 4.1E-13 T 12-10-2018 IPR006549 HAD-superfamily hydrolase,subfamily IIIA Reactome: R-HSA-5649702 VAPA_1c23920 5ea8f3c5e27dc8d7b1da4a0a333abc1b 321 SUPERFAMILY SSF51430 4 316 2.1E-92 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily VAPA_1c23920 5ea8f3c5e27dc8d7b1da4a0a333abc1b 321 Gene3D G3DSA:3.20.20.100 2 321 3.7E-101 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily VAPA_1c23920 5ea8f3c5e27dc8d7b1da4a0a333abc1b 321 Pfam PF00248 Aldo/keto reductase family 16 315 1.6E-67 T 12-10-2018 IPR023210 NADP-dependent oxidoreductase domain VAPA_2c10900 bfdc6a210f39fcd1ac66c67547a0e7a1 331 PIRSF PIRSF017082 1 331 1.5E-64 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_2c10900 bfdc6a210f39fcd1ac66c67547a0e7a1 331 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 56 322 3.8E-65 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_2c10900 bfdc6a210f39fcd1ac66c67547a0e7a1 331 SUPERFAMILY SSF53850 122 289 3.5E-15 T 12-10-2018 VAPA_2c10900 bfdc6a210f39fcd1ac66c67547a0e7a1 331 Gene3D G3DSA:3.40.190.150 37 320 8.7E-93 T 12-10-2018 VAPA_2c10900 bfdc6a210f39fcd1ac66c67547a0e7a1 331 Gene3D G3DSA:3.40.190.10 135 256 8.7E-93 T 12-10-2018 VAPA_1c36990 9f6a5ab0ab7e9ecbe4f05e1c5615e5c8 781 SUPERFAMILY SSF117074 61 115 5.89E-7 T 12-10-2018 VAPA_1c36990 9f6a5ab0ab7e9ecbe4f05e1c5615e5c8 781 Pfam PF04185 Phosphoesterase family 260 699 1.5E-4 T 12-10-2018 IPR007312 Phosphoesterase GO:0016788 VAPA_2c13250 dee026cf46a718831ceda6eb5049fa02 280 Pfam PF03524 Conjugal transfer protein 41 252 7.4E-56 T 12-10-2018 IPR010258 Conjugal transfer, TrbG/VirB9/CagX VAPA_2c13250 dee026cf46a718831ceda6eb5049fa02 280 Gene3D G3DSA:2.60.40.2500 152 279 3.8E-31 T 12-10-2018 IPR038161 VirB9/CagX/TrbG, C-terminal domain superfamily VAPA_1c29390 31093d73142cbbde92a3e918a7ba8206 241 SUPERFAMILY SSF53098 14 205 5.01E-64 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily VAPA_1c29390 31093d73142cbbde92a3e918a7ba8206 241 Pfam PF01351 Ribonuclease HII 23 199 2.2E-37 T 12-10-2018 IPR024567 Ribonuclease HII/HIII domain VAPA_1c29390 31093d73142cbbde92a3e918a7ba8206 241 Gene3D G3DSA:3.30.420.10 2 220 1.8E-75 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 VAPA_1c29390 31093d73142cbbde92a3e918a7ba8206 241 Hamap MF_00052_B Ribonuclease HII [rnhB]. 21 200 36.116 T 12-10-2018 IPR022898 Ribonuclease HII GO:0004523 VAPA_1c20530 f93d740ddca3c991ec9c8ff678f050d0 303 SUPERFAMILY SSF46785 4 115 4.28E-21 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c20530 f93d740ddca3c991ec9c8ff678f050d0 303 SUPERFAMILY SSF53850 92 295 1.99E-47 T 12-10-2018 VAPA_1c20530 f93d740ddca3c991ec9c8ff678f050d0 303 Pfam PF03466 LysR substrate binding domain 91 291 4.5E-44 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_1c20530 f93d740ddca3c991ec9c8ff678f050d0 303 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 9 66 3.5E-17 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c20530 f93d740ddca3c991ec9c8ff678f050d0 303 Gene3D G3DSA:1.10.10.10 4 89 9.0E-23 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c20530 f93d740ddca3c991ec9c8ff678f050d0 303 Gene3D G3DSA:3.40.190.290 95 291 1.7E-63 T 12-10-2018 VAPA_1c42190 872e82b203867e24735e4498e2fd8569 189 Pfam PF11749 Protein of unknown function (DUF3305) 15 159 1.6E-51 T 12-10-2018 IPR021736 Protein of unknown function DUF3305 VAPA_1c46120 cb20ac553fd44a9d0fa04dc9a4e006e9 261 Gene3D G3DSA:1.10.10.10 4 84 1.4E-18 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c46120 cb20ac553fd44a9d0fa04dc9a4e006e9 261 SUPERFAMILY SSF46785 18 90 2.31E-12 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c46120 cb20ac553fd44a9d0fa04dc9a4e006e9 261 SMART SM00346 18 106 2.0E-23 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 VAPA_1c46120 cb20ac553fd44a9d0fa04dc9a4e006e9 261 SUPERFAMILY SSF55781 83 261 2.62E-51 T 12-10-2018 VAPA_1c46120 cb20ac553fd44a9d0fa04dc9a4e006e9 261 Gene3D G3DSA:3.30.450.40 85 261 1.2E-58 T 12-10-2018 IPR029016 GAF-like domain superfamily VAPA_1c46120 cb20ac553fd44a9d0fa04dc9a4e006e9 261 TIGRFAM TIGR02431 pcaR_pcaU: beta-ketoadipate pathway transcriptional regulators, PcaR/PcaU/PobR family 15 261 1.9E-100 T 12-10-2018 IPR012794 Beta-ketoadipate transcriptional regulator, PcaR/PcaU/PobR GO:0003677|GO:0045893|GO:0046278 VAPA_1c46120 cb20ac553fd44a9d0fa04dc9a4e006e9 261 Pfam PF01614 Bacterial transcriptional regulator 134 259 3.9E-36 T 12-10-2018 IPR014757 Transcription regulator IclR, C-terminal VAPA_1c46120 cb20ac553fd44a9d0fa04dc9a4e006e9 261 Pfam PF09339 IclR helix-turn-helix domain 22 71 8.6E-13 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 VAPA_1c38370 74bae77f1ffc3d0a7b99d86627d885b0 189 Pfam PF12804 MobA-like NTP transferase domain 48 149 1.0E-18 T 12-10-2018 IPR025877 MobA-like NTP transferase VAPA_1c38370 74bae77f1ffc3d0a7b99d86627d885b0 189 Gene3D G3DSA:3.90.550.10 6 51 1.3E-8 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases VAPA_1c38370 74bae77f1ffc3d0a7b99d86627d885b0 189 Gene3D G3DSA:3.90.550.10 52 180 7.1E-26 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases VAPA_1c38370 74bae77f1ffc3d0a7b99d86627d885b0 189 SUPERFAMILY SSF53448 9 175 1.8E-25 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases VAPA_1c15550 2e17600467a2c8eb9fc404c9a2478a7f 203 Gene3D G3DSA:3.40.50.850 1 186 7.4E-32 T 12-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 VAPA_1c15550 2e17600467a2c8eb9fc404c9a2478a7f 203 Pfam PF00857 Isochorismatase family 3 168 1.8E-20 T 12-10-2018 IPR000868 Isochorismatase-like GO:0003824 VAPA_1c15550 2e17600467a2c8eb9fc404c9a2478a7f 203 SUPERFAMILY SSF52499 2 182 7.98E-33 T 12-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 VAPA_1c46190 1acd8169c32fe543d5b79ad6a71a9a17 329 TIGRFAM TIGR03177 pilus_cpaB: Flp pilus assembly protein CpaB 11 324 8.5E-51 T 12-10-2018 IPR017592 Pilus assembly, Flp-type CpaB VAPA_1c46190 1acd8169c32fe543d5b79ad6a71a9a17 329 Pfam PF16976 Flp pilus assembly protein RcpC/CpaB 114 233 2.7E-30 T 12-10-2018 IPR031571 Flp pilus assembly protein RcpC/CpaB domain VAPA_1c46190 1acd8169c32fe543d5b79ad6a71a9a17 329 SMART SM00858 52 112 2.0E-8 T 12-10-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 VAPA_1c12520 49daac425f92256c65de0c4c5041d3f6 381 SUPERFAMILY SSF53756 3 302 1.0E-4 T 12-10-2018 VAPA_1c12520 49daac425f92256c65de0c4c5041d3f6 381 Pfam PF04230 Polysaccharide pyruvyl transferase 14 323 3.2E-25 T 12-10-2018 IPR007345 Polysaccharide pyruvyl transferase VAPA_1c19000 95f48689b7d9f2778d9b7483eb58353c 273 Hamap MF_01062 Phosphoenolpyruvate synthase regulatory protein [ppsR]. 3 272 74.891 T 12-10-2018 IPR026530 Phosphoenolpyruvate synthase regulatory protein VAPA_1c19000 95f48689b7d9f2778d9b7483eb58353c 273 Pfam PF03618 Kinase/pyrophosphorylase 6 263 1.4E-80 T 12-10-2018 IPR005177 Bifunctional kinase-pyrophosphorylase GO:0005524|GO:0016772 VAPA_1c19270 d9adfa0b967dff291d9efb50f7fe4fc9 275 SMART SM00382 36 251 9.4E-10 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c19270 d9adfa0b967dff291d9efb50f7fe4fc9 275 Pfam PF00005 ABC transporter 27 179 5.1E-26 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c19270 d9adfa0b967dff291d9efb50f7fe4fc9 275 ProSitePatterns PS00211 ABC transporters family signature. 152 166 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_1c19270 d9adfa0b967dff291d9efb50f7fe4fc9 275 SUPERFAMILY SSF52540 9 251 1.96E-52 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c19270 d9adfa0b967dff291d9efb50f7fe4fc9 275 Gene3D G3DSA:3.40.50.300 6 253 4.1E-54 T 12-10-2018 VAPA_1c09940 5d631828f23f52f94a97b6ddb09f9d63 486 PIRSF PIRSF004919 23 486 3.6E-132 T 12-10-2018 IPR025502 TldD VAPA_1c09940 5d631828f23f52f94a97b6ddb09f9d63 486 Gene3D G3DSA:3.30.2290.10 23 245 3.1E-18 T 12-10-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal VAPA_1c09940 5d631828f23f52f94a97b6ddb09f9d63 486 Pfam PF01523 Putative modulator of DNA gyrase 43 337 8.7E-68 T 12-10-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 VAPA_1c09940 5d631828f23f52f94a97b6ddb09f9d63 486 SUPERFAMILY SSF111283 27 485 1.16E-130 T 12-10-2018 IPR036059 Metalloprotease TldD/PmbA superfamily GO:0006508|GO:0008237 VAPA_1c27300 c88c9aa6c7eecfd98bf1e9693984262e 88 Pfam PF05751 FixH 21 71 3.2E-12 T 12-10-2018 IPR008620 Nitrogen fixation protein FixH VAPA_1c48810 54b8f05a66cd6755830819a0e45ce30d 230 Pfam PF13419 Haloacid dehalogenase-like hydrolase 9 188 1.0E-21 T 12-10-2018 VAPA_1c48810 54b8f05a66cd6755830819a0e45ce30d 230 Gene3D G3DSA:1.10.150.240 21 87 2.0E-55 T 12-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 VAPA_1c48810 54b8f05a66cd6755830819a0e45ce30d 230 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 70 189 2.8E-13 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 VAPA_1c48810 54b8f05a66cd6755830819a0e45ce30d 230 SUPERFAMILY SSF56784 6 223 6.82E-50 T 12-10-2018 IPR036412 HAD-like superfamily VAPA_1c48810 54b8f05a66cd6755830819a0e45ce30d 230 Gene3D G3DSA:3.40.50.1000 8 211 2.0E-55 T 12-10-2018 IPR023214 HAD superfamily VAPA_1c01850 63b846785124f540a900467900270127 396 SUPERFAMILY SSF53590 47 386 4.58E-61 T 12-10-2018 IPR036452 Ribonucleoside hydrolase-like VAPA_1c01850 63b846785124f540a900467900270127 396 Gene3D G3DSA:3.90.245.10 45 386 8.8E-74 T 12-10-2018 IPR036452 Ribonucleoside hydrolase-like VAPA_1c01850 63b846785124f540a900467900270127 396 Pfam PF01156 Inosine-uridine preferring nucleoside hydrolase 47 378 2.5E-57 T 12-10-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain VAPA_1c01590 814fa1875747e4f7c2e205adeef8e289 330 Gene3D G3DSA:3.40.50.720 1 319 3.6E-33 T 12-10-2018 VAPA_1c01590 814fa1875747e4f7c2e205adeef8e289 330 SUPERFAMILY SSF51735 5 316 4.42E-43 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c01590 814fa1875747e4f7c2e205adeef8e289 330 Pfam PF13460 NAD(P)H-binding 11 167 1.7E-13 T 12-10-2018 IPR016040 NAD(P)-binding domain VAPA_1c54820 ffe1abdec3a2a4c242f3778b997c24e2 159 Gene3D G3DSA:3.30.370.10 63 151 8.7E-12 T 12-10-2018 IPR035905 Barstar-like superfamily VAPA_1c54820 ffe1abdec3a2a4c242f3778b997c24e2 159 Pfam PF01337 Barstar (barnase inhibitor) 64 147 7.0E-26 T 12-10-2018 IPR000468 Barstar (barnase inhibitor) VAPA_1c54820 ffe1abdec3a2a4c242f3778b997c24e2 159 SUPERFAMILY SSF52038 60 152 4.58E-24 T 12-10-2018 IPR035905 Barstar-like superfamily VAPA_1c40110 48951179c1b4b91e23528da8a343bd74 394 SUPERFAMILY SSF48208 12 391 4.2E-38 T 12-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 VAPA_1c40110 48951179c1b4b91e23528da8a343bd74 394 Pfam PF12899 Alkaline and neutral invertase 249 387 6.7E-11 T 12-10-2018 IPR024746 Glycosyl hydrolase family 100 GO:0033926 KEGG: 00052+3.2.1.26|KEGG: 00500+3.2.1.26 VAPA_1c50750 a8a8341f4d616a615edc3ccd0042f04a 153 Pfam PF14079 Domain of unknown function (DUF4260) 36 147 5.5E-41 T 12-10-2018 IPR025356 Protein of unknown function DUF4260 VAPA_1c25140 c568e24f41fd9a33bdb6627c682dfe3a 393 SUPERFAMILY SSF56601 133 370 7.85E-57 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like VAPA_1c25140 c568e24f41fd9a33bdb6627c682dfe3a 393 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 131 353 1.6E-56 T 12-10-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 VAPA_1c25140 c568e24f41fd9a33bdb6627c682dfe3a 393 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 211 228 1.5E-12 T 12-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 VAPA_1c25140 c568e24f41fd9a33bdb6627c682dfe3a 393 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 161 172 1.5E-12 T 12-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 VAPA_1c25140 c568e24f41fd9a33bdb6627c682dfe3a 393 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 238 251 1.5E-12 T 12-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 VAPA_1c25140 c568e24f41fd9a33bdb6627c682dfe3a 393 Gene3D G3DSA:3.40.710.10 105 390 5.9E-65 T 12-10-2018 VAPA_1c47960 ce883650da4f90374c4fc0507ef94988 62 Pfam PF11174 Protein of unknown function (DUF2970) 4 58 2.3E-9 T 12-10-2018 IPR021344 Protein of unknown function DUF2970 VAPA_2c05390 7822c71e05489e3f8fc7d2db91aff5da 207 SUPERFAMILY SSF52833 1 78 4.07E-13 T 12-10-2018 IPR036249 Thioredoxin-like superfamily VAPA_2c05390 7822c71e05489e3f8fc7d2db91aff5da 207 Gene3D G3DSA:1.20.1050.10 84 192 1.4E-21 T 12-10-2018 VAPA_2c05390 7822c71e05489e3f8fc7d2db91aff5da 207 Gene3D G3DSA:3.40.30.10 1 79 1.3E-12 T 12-10-2018 VAPA_2c05390 7822c71e05489e3f8fc7d2db91aff5da 207 Pfam PF13417 Glutathione S-transferase, N-terminal domain 3 77 1.9E-8 T 12-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 VAPA_2c05390 7822c71e05489e3f8fc7d2db91aff5da 207 SUPERFAMILY SSF47616 88 193 5.57E-21 T 12-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily VAPA_2c05390 7822c71e05489e3f8fc7d2db91aff5da 207 Pfam PF13410 Glutathione S-transferase, C-terminal domain 125 182 7.7E-8 T 12-10-2018 VAPA_1c05580 5d688bfde65057c4785ed8da49e8c906 288 SUPERFAMILY SSF56112 81 188 4.34E-5 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily VAPA_1c18250 66a972222b0cb4a9c092006b76ea81e2 372 Pfam PF12698 ABC-2 family transporter protein 29 364 3.0E-45 T 12-10-2018 VAPA_1c18250 66a972222b0cb4a9c092006b76ea81e2 372 PRINTS PR00164 ABC-2 type transport system membrane protein signature 314 333 8.9E-6 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 VAPA_1c18250 66a972222b0cb4a9c092006b76ea81e2 372 PRINTS PR00164 ABC-2 type transport system membrane protein signature 294 313 8.9E-6 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 VAPA_1c18250 66a972222b0cb4a9c092006b76ea81e2 372 PRINTS PR00164 ABC-2 type transport system membrane protein signature 257 281 8.9E-6 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 VAPA_1c05640 4fd6d79d89acd8dd90f50c2146532fb0 180 Gene3D G3DSA:3.90.950.20 3 169 1.3E-62 T 12-10-2018 IPR036653 CinA-like, C-terminal VAPA_1c05640 4fd6d79d89acd8dd90f50c2146532fb0 180 TIGRFAM TIGR00199 PncC_domain: amidohydrolase, PncC family 24 166 3.3E-46 T 12-10-2018 IPR008136 CinA, C-terminal VAPA_1c05640 4fd6d79d89acd8dd90f50c2146532fb0 180 SUPERFAMILY SSF142433 12 169 1.7E-56 T 12-10-2018 IPR036653 CinA-like, C-terminal VAPA_1c05640 4fd6d79d89acd8dd90f50c2146532fb0 180 Pfam PF02464 Competence-damaged protein 19 166 7.7E-59 T 12-10-2018 IPR008136 CinA, C-terminal VAPA_1c25720 cd999def52d7647a46f22dca3883bdfc 345 ProSitePatterns PS00401 Prokaryotic sulfate-binding proteins signature 1. 61 73 - T 12-10-2018 IPR000957 Sulphate/thiosulphate-binding, conserved site VAPA_1c25720 cd999def52d7647a46f22dca3883bdfc 345 ProSitePatterns PS00757 Prokaryotic sulfate-binding proteins signature 2. 159 167 - T 12-10-2018 IPR034408 Sulphate/thiosulphate-binding site GO:1901681 VAPA_1c25720 cd999def52d7647a46f22dca3883bdfc 345 SUPERFAMILY SSF53850 34 341 1.02E-83 T 12-10-2018 VAPA_1c25720 cd999def52d7647a46f22dca3883bdfc 345 Gene3D G3DSA:3.40.190.10 40 308 6.9E-129 T 12-10-2018 VAPA_1c25720 cd999def52d7647a46f22dca3883bdfc 345 Pfam PF13531 Bacterial extracellular solute-binding protein 53 293 1.2E-43 T 12-10-2018 VAPA_1c25720 cd999def52d7647a46f22dca3883bdfc 345 Gene3D G3DSA:3.40.190.10 128 338 6.9E-129 T 12-10-2018 VAPA_1c25720 cd999def52d7647a46f22dca3883bdfc 345 TIGRFAM TIGR00971 3a0106s03: sulfate ABC transporter, sulfate-binding protein 33 339 1.1E-139 T 12-10-2018 IPR005669 Thiosulphate/Sulfate-binding protein GO:0008272|GO:0015419 VAPA_2c09570 960a715f072d33c3abcc901f744c22cc 451 Pfam PF05598 Transposase domain (DUF772) 52 121 3.4E-16 T 12-10-2018 IPR008490 Transposase InsH, N-terminal VAPA_2c09570 960a715f072d33c3abcc901f744c22cc 451 Pfam PF01609 Transposase DDE domain 275 442 6.9E-19 T 12-10-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 VAPA_2c05130 3f8861dce7e005dadc58dab974d025fe 117 SUPERFAMILY SSF51316 1 114 2.09E-30 T 12-10-2018 IPR011057 Mss4-like superfamily VAPA_2c05130 3f8861dce7e005dadc58dab974d025fe 117 Pfam PF04828 Glutathione-dependent formaldehyde-activating enzyme 27 102 1.0E-7 T 12-10-2018 IPR006913 Glutathione-dependent formaldehyde-activating enzyme/centromere protein V GO:0016846 KEGG: 00680+4.4.1.22|MetaCyc: PWY-1801 VAPA_2c05130 3f8861dce7e005dadc58dab974d025fe 117 Gene3D G3DSA:2.170.150.70 5 117 2.0E-30 T 12-10-2018 VAPA_1c31910 c682c99f1142c5a8a94aa3254f14cddf 522 Pfam PF01970 Tripartite tricarboxylate transporter TctA family 22 441 4.3E-134 T 12-10-2018 IPR002823 Protein of unknown function DUF112, transmembrane VAPA_1c00670 7904bc8e4788c69c9afd6977ea4a3d70 428 TIGRFAM TIGR00801 ncs2: uracil-xanthine permease 23 420 7.8E-110 T 12-10-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 VAPA_1c00670 7904bc8e4788c69c9afd6977ea4a3d70 428 ProSitePatterns PS01116 Xanthine/uracil permeases family signature. 345 365 - T 12-10-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 VAPA_1c00670 7904bc8e4788c69c9afd6977ea4a3d70 428 Pfam PF00860 Permease family 28 398 4.9E-90 T 12-10-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0016020|GO:0022857|GO:0055085 VAPA_1c01000 2b4019cabb5c0d0d27c316f719c4f7b6 344 SUPERFAMILY SSF53474 46 341 5.94E-21 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c01000 2b4019cabb5c0d0d27c316f719c4f7b6 344 PIRSF PIRSF031982 1 344 1.7E-57 T 12-10-2018 IPR016986 Uncharacterised conserved protein UCP031982, alpha/beta hydrolase, XabL VAPA_1c41350 134e61b6b60bac7fc3f5c8eb72f03147 437 Pfam PF13701 Transposase DDE domain group 1 14 435 8.4E-149 T 12-10-2018 IPR025668 Transposase DDE domain VAPA_2c11380 62c5f36d034c33786055fe1980374138 288 Pfam PF02653 Branched-chain amino acid transport system / permease component 8 272 1.4E-32 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 VAPA_1c31840 d651b0ad05cc3624013ec2f428b138fa 145 Gene3D G3DSA:3.30.420.270 60 137 7.4E-12 T 12-10-2018 VAPA_1c31840 d651b0ad05cc3624013ec2f428b138fa 145 Pfam PF02472 Biopolymer transport protein ExbD/TolR 12 141 1.0E-28 T 12-10-2018 IPR003400 Biopolymer transport protein ExbD/TolR GO:0022857|GO:0055085 VAPA_2c09980 5d708643e004618420df7d1df625d551 195 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 28 51 7.7E-10 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 VAPA_2c09980 5d708643e004618420df7d1df625d551 195 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 7 20 7.7E-10 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 VAPA_2c09980 5d708643e004618420df7d1df625d551 195 SUPERFAMILY SSF48498 73 176 6.43E-16 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily VAPA_2c09980 5d708643e004618420df7d1df625d551 195 SUPERFAMILY SSF46689 3 78 7.18E-20 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 VAPA_2c09980 5d708643e004618420df7d1df625d551 195 Gene3D G3DSA:1.10.357.10 1 188 1.1E-60 T 12-10-2018 VAPA_2c09980 5d708643e004618420df7d1df625d551 195 Pfam PF00440 Bacterial regulatory proteins, tetR family 7 53 1.4E-15 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 VAPA_1c42750 d9f4297d543bb248b940c949ceeb806d 250 SUPERFAMILY SSF56219 5 247 4.06E-48 T 12-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily VAPA_1c42750 d9f4297d543bb248b940c949ceeb806d 250 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 11 240 3.4E-13 T 12-10-2018 IPR005135 Endonuclease/exonuclease/phosphatase VAPA_1c42750 d9f4297d543bb248b940c949ceeb806d 250 Gene3D G3DSA:3.60.10.10 7 250 5.2E-45 T 12-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily VAPA_1c53720 d6e6e0291418681daa3ee54b1241ed24 148 Pfam PF07963 Prokaryotic N-terminal methylation motif 18 42 2.1E-4 T 12-10-2018 IPR012902 Prokaryotic N-terminal methylation site VAPA_1c34130 181dd3d7ac1631c70d58e44f2e292055 225 Pfam PF02230 Phospholipase/Carboxylesterase 16 216 2.9E-22 T 12-10-2018 IPR003140 Phospholipase/carboxylesterase/thioesterase GO:0016787 VAPA_1c34130 181dd3d7ac1631c70d58e44f2e292055 225 SUPERFAMILY SSF53474 22 216 2.89E-40 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c34130 181dd3d7ac1631c70d58e44f2e292055 225 Gene3D G3DSA:3.40.50.1820 2 219 2.6E-45 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c25390 07f2cece9d707e37bd406eaafb20cd93 446 Gene3D G3DSA:1.10.4160.10 2 368 2.8E-32 T 12-10-2018 IPR038271 Purine-cytosine permease superfamily VAPA_1c25390 07f2cece9d707e37bd406eaafb20cd93 446 Pfam PF02133 Permease for cytosine/purines, uracil, thiamine, allantoin 16 367 2.7E-11 T 12-10-2018 IPR001248 Purine-cytosine permease GO:0016020|GO:0022857|GO:0055085 VAPA_2c08120 3e8a4d9bcbee56b583023c01f32ebc86 278 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 103 276 3.7E-20 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 VAPA_2c08120 3e8a4d9bcbee56b583023c01f32ebc86 278 SUPERFAMILY SSF161098 81 261 1.44E-26 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_2c08120 3e8a4d9bcbee56b583023c01f32ebc86 278 Gene3D G3DSA:1.10.3720.10 81 276 3.1E-23 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_2c08470 de470d7aacc67d72fc91283e68b5c941 270 Gene3D G3DSA:3.40.50.1820 13 270 1.4E-45 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_2c08470 de470d7aacc67d72fc91283e68b5c941 270 Pfam PF12697 Alpha/beta hydrolase family 42 261 2.4E-19 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 VAPA_2c08470 de470d7aacc67d72fc91283e68b5c941 270 SUPERFAMILY SSF53474 36 266 1.77E-35 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c27910 ff9a54169d72e2c3c48a1536ae226104 125 Gene3D G3DSA:1.10.10.10 12 122 7.3E-39 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c27910 ff9a54169d72e2c3c48a1536ae226104 125 SUPERFAMILY SSF46785 14 115 7.61E-32 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c27910 ff9a54169d72e2c3c48a1536ae226104 125 Pfam PF01638 HxlR-like helix-turn-helix 25 113 1.1E-28 T 12-10-2018 IPR002577 Helix-turn-helix, HxlR type VAPA_1c35670 a492f33a723a9fc86ce88711582e02d1 305 Gene3D G3DSA:1.20.1530.20 165 303 1.4E-5 T 12-10-2018 IPR038770 Sodium/solute symporter superfamily VAPA_1c35670 a492f33a723a9fc86ce88711582e02d1 305 Pfam PF03547 Membrane transport protein 151 299 6.9E-9 T 12-10-2018 IPR004776 Membrane transport protein GO:0016021|GO:0055085 VAPA_1c53230 ab3c8ab0937b3819ac01806c482489dd 273 SUPERFAMILY SSF102215 8 260 7.72E-69 T 12-10-2018 IPR024087 Creatininase-like superfamily KEGG: 00740+3.5.1.102|MetaCyc: PWY-6167 VAPA_1c53230 ab3c8ab0937b3819ac01806c482489dd 273 Gene3D G3DSA:3.40.50.10310 4 260 3.8E-67 T 12-10-2018 IPR024087 Creatininase-like superfamily KEGG: 00740+3.5.1.102|MetaCyc: PWY-6167 VAPA_1c53230 ab3c8ab0937b3819ac01806c482489dd 273 Pfam PF02633 Creatinine amidohydrolase 13 254 7.4E-63 T 12-10-2018 IPR003785 Creatininase/formamide hydrolase KEGG: 00740+3.5.1.102|MetaCyc: PWY-6167 VAPA_2c12110 2ed885f1f7d210a30942c08f42785e5d 374 SUPERFAMILY SSF56935 22 374 2.11E-59 T 12-10-2018 VAPA_2c12110 2ed885f1f7d210a30942c08f42785e5d 374 Pfam PF13609 Gram-negative porin 15 345 1.1E-49 T 12-10-2018 VAPA_2c12110 2ed885f1f7d210a30942c08f42785e5d 374 Gene3D G3DSA:2.40.160.10 22 374 4.0E-72 T 12-10-2018 IPR023614 Porin domain superfamily VAPA_1c44360 07cb22aace867ab199e88dced2736479 586 SUPERFAMILY SSF50494 402 569 6.35E-18 T 12-10-2018 IPR009003 Peptidase S1, PA clan VAPA_1c44360 07cb22aace867ab199e88dced2736479 586 Pfam PF13365 Trypsin-like peptidase domain 409 559 1.1E-12 T 12-10-2018 VAPA_1c44360 07cb22aace867ab199e88dced2736479 586 Gene3D G3DSA:2.40.10.10 394 483 2.5E-6 T 12-10-2018 VAPA_1c44360 07cb22aace867ab199e88dced2736479 586 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 48 257 4.5E-19 T 12-10-2018 IPR000477 Reverse transcriptase domain VAPA_1c44360 07cb22aace867ab199e88dced2736479 586 Gene3D G3DSA:2.40.10.10 490 584 4.1E-7 T 12-10-2018 VAPA_1c44360 07cb22aace867ab199e88dced2736479 586 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 174 187 3.2E-29 T 12-10-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 VAPA_1c44360 07cb22aace867ab199e88dced2736479 586 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 89 103 3.2E-29 T 12-10-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 VAPA_1c44360 07cb22aace867ab199e88dced2736479 586 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 156 169 3.2E-29 T 12-10-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 VAPA_1c44360 07cb22aace867ab199e88dced2736479 586 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 189 200 3.2E-29 T 12-10-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 VAPA_1c44360 07cb22aace867ab199e88dced2736479 586 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 43 56 3.2E-29 T 12-10-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 VAPA_1c44360 07cb22aace867ab199e88dced2736479 586 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 254 260 3.2E-29 T 12-10-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 VAPA_1c44360 07cb22aace867ab199e88dced2736479 586 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 57 69 3.2E-29 T 12-10-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 VAPA_1c44360 07cb22aace867ab199e88dced2736479 586 SUPERFAMILY SSF56672 41 206 8.56E-8 T 12-10-2018 VAPA_1c54930 ca29daf051c7ca91158e3215d43ca043 503 SUPERFAMILY SSF53187 24 489 1.08E-46 T 12-10-2018 VAPA_1c54930 ca29daf051c7ca91158e3215d43ca043 503 Gene3D G3DSA:3.40.630.10 368 493 2.7E-20 T 12-10-2018 VAPA_1c54930 ca29daf051c7ca91158e3215d43ca043 503 Gene3D G3DSA:3.40.630.10 14 240 1.8E-52 T 12-10-2018 VAPA_1c54930 ca29daf051c7ca91158e3215d43ca043 503 Pfam PF01546 Peptidase family M20/M25/M40 107 487 3.6E-22 T 12-10-2018 IPR002933 Peptidase M20 GO:0016787 VAPA_1c54930 ca29daf051c7ca91158e3215d43ca043 503 Pfam PF07687 Peptidase dimerisation domain 219 386 6.6E-13 T 12-10-2018 IPR011650 Peptidase M20, dimerisation domain VAPA_1c23060 d8891abb6b1f4be278c6033e208cb1b3 212 PIRSF PIRSF006324 1 209 1.2E-52 T 12-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 VAPA_1c23060 d8891abb6b1f4be278c6033e208cb1b3 212 Pfam PF01810 LysE type translocator 15 205 3.2E-33 T 12-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 VAPA_1c50600 279258f100d127dddac092dc5e05ff0f 161 Pfam PF03899 ATP synthase I chain 44 139 7.5E-15 T 12-10-2018 IPR005598 ATP synthase protein I VAPA_2c02050 9c6dc769f4a2240383af6cc7f74f8da6 95 Gene3D G3DSA:2.40.50.320 23 95 5.0E-24 T 12-10-2018 VAPA_2c02050 9c6dc769f4a2240383af6cc7f74f8da6 95 Pfam PF11604 Copper binding periplasmic protein CusF 27 93 2.0E-26 T 12-10-2018 IPR021647 Copper binding periplasmic protein CusF VAPA_1c39560 10d79ae53b3163c3a2ddc80c039a64d8 294 SUPERFAMILY SSF161098 95 281 6.8E-39 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c39560 10d79ae53b3163c3a2ddc80c039a64d8 294 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 118 287 9.6E-28 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 VAPA_1c39560 10d79ae53b3163c3a2ddc80c039a64d8 294 Gene3D G3DSA:1.10.3720.10 91 288 6.5E-32 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c14600 ec00302d52785b53e93dffaf24824af7 177 SUPERFAMILY SSF55729 21 176 3.09E-28 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase VAPA_1c14600 ec00302d52785b53e93dffaf24824af7 177 Pfam PF13420 Acetyltransferase (GNAT) domain 24 170 2.0E-19 T 12-10-2018 VAPA_1c14600 ec00302d52785b53e93dffaf24824af7 177 Gene3D G3DSA:3.40.630.30 12 177 6.1E-50 T 12-10-2018 VAPA_1c10740 8869dfa9efb5dfa7c763bea19a7dc3ff 89 Pfam PF13560 Helix-turn-helix domain 22 75 1.9E-6 T 12-10-2018 VAPA_1c10740 8869dfa9efb5dfa7c763bea19a7dc3ff 89 SUPERFAMILY SSF47413 20 86 7.11E-8 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 VAPA_1c10740 8869dfa9efb5dfa7c763bea19a7dc3ff 89 Gene3D G3DSA:1.10.260.40 11 88 4.3E-8 T 12-10-2018 VAPA_1c11560 fc2784dc63fa461b8d04c82d3c8e0206 213 Pfam PF13419 Haloacid dehalogenase-like hydrolase 114 189 2.9E-7 T 12-10-2018 VAPA_1c11560 fc2784dc63fa461b8d04c82d3c8e0206 213 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 134 190 2.2E-14 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 VAPA_1c11560 fc2784dc63fa461b8d04c82d3c8e0206 213 SUPERFAMILY SSF56784 3 199 4.29E-33 T 12-10-2018 IPR036412 HAD-like superfamily VAPA_1c11560 fc2784dc63fa461b8d04c82d3c8e0206 213 Gene3D G3DSA:3.40.50.1000 2 205 1.2E-33 T 12-10-2018 IPR023214 HAD superfamily VAPA_2c00590 5c79e4e04693585494f5afa9a92624b7 239 SUPERFAMILY SSF52540 2 235 5.22E-56 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_2c00590 5c79e4e04693585494f5afa9a92624b7 239 SMART SM00382 27 212 1.5E-12 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_2c00590 5c79e4e04693585494f5afa9a92624b7 239 Pfam PF00005 ABC transporter 18 164 2.1E-31 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_2c00590 5c79e4e04693585494f5afa9a92624b7 239 Gene3D G3DSA:3.40.50.300 1 237 2.6E-61 T 12-10-2018 VAPA_1c16680 35be71f3634141b93970fc9e966bf107 607 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 13 523 8.0E-118 T 12-10-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit VAPA_1c04300 972766d2f45bcffb2ec74dfb6f07eae0 327 Pfam PF02653 Branched-chain amino acid transport system / permease component 35 297 6.5E-49 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 VAPA_2c09070 409e74d01241add5d4d9f378e13ac013 208 Gene3D G3DSA:3.40.30.10 21 195 5.3E-37 T 12-10-2018 VAPA_2c09070 409e74d01241add5d4d9f378e13ac013 208 SUPERFAMILY SSF52833 26 195 6.35E-34 T 12-10-2018 IPR036249 Thioredoxin-like superfamily VAPA_2c09070 409e74d01241add5d4d9f378e13ac013 208 Pfam PF00578 AhpC/TSA family 28 173 2.3E-30 T 12-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 VAPA_1c31470 563c710c98f41e87c4b24b2c525c3425 383 PIRSF PIRSF016817 1 383 4.1E-82 T 12-10-2018 IPR016677 Uncharacterised conserved protein UCP016817, ATP-dependent carboligase VAPA_1c31470 563c710c98f41e87c4b24b2c525c3425 383 Gene3D G3DSA:3.30.1490.350 130 177 5.3E-16 T 12-10-2018 VAPA_1c31470 563c710c98f41e87c4b24b2c525c3425 383 Gene3D G3DSA:3.30.470.20 127 271 5.3E-16 T 12-10-2018 VAPA_1c31470 563c710c98f41e87c4b24b2c525c3425 383 Pfam PF02655 ATP-grasp domain 120 269 9.7E-19 T 12-10-2018 IPR003806 ATP-grasp fold, DUF201-type GO:0005524|GO:0046872 VAPA_1c31470 563c710c98f41e87c4b24b2c525c3425 383 SUPERFAMILY SSF56059 111 301 1.06E-14 T 12-10-2018 VAPA_1c01430 6e45f5b5956adf370af4dacc99bd183c 63 Pfam PF06568 Domain of unknown function (DUF1127) 17 55 1.0E-7 T 12-10-2018 IPR009506 Protein of unknown function DUF1127 VAPA_1c01330 9f0ccfc17965bd3974137e510080941d 437 Pfam PF13701 Transposase DDE domain group 1 14 435 1.4E-148 T 12-10-2018 IPR025668 Transposase DDE domain VAPA_1c20070 efc52934f6213137ee14ba58e0c64e39 101 Pfam PF03551 Transcriptional regulator PadR-like family 15 85 2.3E-19 T 12-10-2018 IPR005149 Transcription regulator PadR, N-terminal VAPA_1c20070 efc52934f6213137ee14ba58e0c64e39 101 SUPERFAMILY SSF46785 4 97 4.36E-24 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c20070 efc52934f6213137ee14ba58e0c64e39 101 Gene3D G3DSA:1.10.10.10 1 100 1.7E-24 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c18410 7af39e22ffc607458f2267dfc8aff52f 299 SMART SM00849 43 228 8.1E-19 T 12-10-2018 IPR001279 Metallo-beta-lactamase VAPA_1c18410 7af39e22ffc607458f2267dfc8aff52f 299 SUPERFAMILY SSF56281 28 254 1.27E-40 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like VAPA_1c18410 7af39e22ffc607458f2267dfc8aff52f 299 Gene3D G3DSA:3.60.15.10 31 266 1.1E-28 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like VAPA_1c18410 7af39e22ffc607458f2267dfc8aff52f 299 Pfam PF00753 Metallo-beta-lactamase superfamily 44 228 6.1E-12 T 12-10-2018 IPR001279 Metallo-beta-lactamase VAPA_1c20250 b228628cc9bfc0da0cb80a470e6f38b0 352 Pfam PF05853 beta-keto acid cleavage enzyme 15 317 2.1E-64 T 12-10-2018 IPR008567 3-keto-5-aminohexanoate cleavage enzyme GO:0016740|GO:0019475 KEGG: 00310+2.3.1.247 VAPA_1c20250 b228628cc9bfc0da0cb80a470e6f38b0 352 Gene3D G3DSA:3.20.20.70 10 322 2.5E-67 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 VAPA_1c46160 d7e96e8a639d710b7cdf21d7c3be7b61 447 Gene3D G3DSA:2.40.440.10 146 373 8.0E-22 T 12-10-2018 IPR038063 L,D-transpeptidase catalytic domain-like VAPA_1c46160 d7e96e8a639d710b7cdf21d7c3be7b61 447 Pfam PF03734 L,D-transpeptidase catalytic domain 187 320 3.2E-16 T 12-10-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 VAPA_1c46160 d7e96e8a639d710b7cdf21d7c3be7b61 447 SUPERFAMILY SSF141523 185 317 4.32E-16 T 12-10-2018 IPR038063 L,D-transpeptidase catalytic domain-like VAPA_2c05900 8a7c26f621a5e6cd722dd9a9e9d57fc0 256 SUPERFAMILY SSF53335 64 225 1.58E-35 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase VAPA_2c05900 8a7c26f621a5e6cd722dd9a9e9d57fc0 256 Gene3D G3DSA:3.40.50.150 42 256 1.1E-46 T 12-10-2018 VAPA_2c05900 8a7c26f621a5e6cd722dd9a9e9d57fc0 256 Pfam PF13847 Methyltransferase domain 74 205 1.6E-25 T 12-10-2018 IPR025714 Methyltransferase domain VAPA_2c01570 da0553357dbc1f83b6bd078a54d91a35 482 Pfam PF05598 Transposase domain (DUF772) 56 123 1.9E-17 T 12-10-2018 IPR008490 Transposase InsH, N-terminal VAPA_2c01570 da0553357dbc1f83b6bd078a54d91a35 482 Pfam PF13751 Transposase DDE domain 348 464 1.9E-15 T 12-10-2018 IPR025668 Transposase DDE domain VAPA_1c48920 528ed9d7576ec2503cb50ca78af4450a 142 Gene3D G3DSA:3.10.450.50 5 141 5.0E-30 T 12-10-2018 VAPA_1c48920 528ed9d7576ec2503cb50ca78af4450a 142 SUPERFAMILY SSF54427 39 137 1.23E-28 T 12-10-2018 IPR032710 NTF2-like domain superfamily VAPA_1c40910 77816bbd43699327b57b28e4601d26bc 499 Pfam PF03055 Retinal pigment epithelial membrane protein 57 498 7.4E-89 T 12-10-2018 IPR004294 Carotenoid oxygenase GO:0016702|GO:0055114 VAPA_2c12710 6e5e9828d6b7dd62ed6a11a95a2100fa 471 Pfam PF13546 DDE superfamily endonuclease 14 284 6.9E-99 T 12-10-2018 IPR038721 Transposase IS701-like, DDE domain VAPA_2c12710 6e5e9828d6b7dd62ed6a11a95a2100fa 471 SUPERFAMILY SSF53098 15 398 2.81E-33 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily VAPA_1c11830 3e6f75fc6c759ec6b119a72564bfc7fc 216 SUPERFAMILY SSF161098 13 200 2.49E-45 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c11830 3e6f75fc6c759ec6b119a72564bfc7fc 216 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 35 213 1.2E-19 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 VAPA_1c11830 3e6f75fc6c759ec6b119a72564bfc7fc 216 Gene3D G3DSA:1.10.3720.10 4 216 2.1E-53 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c11830 3e6f75fc6c759ec6b119a72564bfc7fc 216 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 12 109 5.3E-28 T 12-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 VAPA_1c38140 ce521faf1b4c0a2da7ab4817d8a33edd 302 Pfam PF05035 2-keto-3-deoxy-galactonokinase 8 290 9.3E-98 T 12-10-2018 IPR007729 2-keto-3-deoxy-galactonokinase GO:0008671|GO:0034194 KEGG: 00052+2.7.1.58|MetaCyc: PWY-7130 VAPA_1c38140 ce521faf1b4c0a2da7ab4817d8a33edd 302 Gene3D G3DSA:3.30.420.310 78 295 2.5E-70 T 12-10-2018 VAPA_1c38140 ce521faf1b4c0a2da7ab4817d8a33edd 302 Gene3D G3DSA:3.30.420.300 1 77 1.6E-22 T 12-10-2018 VAPA_1c14350 173c2c62c60c786ad593213bb45efd79 357 TIGRFAM TIGR03167 tRNA_sel_U_synt: tRNA 2-selenouridine synthase 20 325 2.4E-105 T 12-10-2018 IPR017582 tRNA 2-selenouridine/geranyl-2-thiouridine synthase GO:0016785|GO:0043828|GO:0070329 VAPA_1c14350 173c2c62c60c786ad593213bb45efd79 357 Pfam PF00581 Rhodanese-like domain 21 131 8.4E-7 T 12-10-2018 IPR001763 Rhodanese-like domain VAPA_1c14350 173c2c62c60c786ad593213bb45efd79 357 Gene3D G3DSA:3.40.250.10 16 137 5.7E-36 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily VAPA_1c14350 173c2c62c60c786ad593213bb45efd79 357 SUPERFAMILY SSF52821 22 136 2.88E-23 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily VAPA_1c14350 173c2c62c60c786ad593213bb45efd79 357 SMART SM00450 7 136 3.9E-8 T 12-10-2018 IPR001763 Rhodanese-like domain VAPA_1c03180 10fe3d3825146ebb765bbd3e01eb0a0e 278 Pfam PF13723 Beta-ketoacyl synthase, N-terminal domain 44 206 1.8E-28 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal VAPA_1c03180 10fe3d3825146ebb765bbd3e01eb0a0e 278 SUPERFAMILY SSF53901 11 191 2.25E-10 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 VAPA_1c37570 8f5b514d65b3e3ae95b43b06d71e718c 221 SUPERFAMILY SSF53474 11 219 1.8E-52 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c37570 8f5b514d65b3e3ae95b43b06d71e718c 221 Gene3D G3DSA:3.40.50.1820 1 220 2.2E-69 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c37570 8f5b514d65b3e3ae95b43b06d71e718c 221 Pfam PF02230 Phospholipase/Carboxylesterase 12 215 8.2E-54 T 12-10-2018 IPR003140 Phospholipase/carboxylesterase/thioesterase GO:0016787 VAPA_1c15880 b28d95b298b13b13abbe87da8e48ccd1 390 SUPERFAMILY SSF53901 242 373 7.49E-18 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 VAPA_1c15880 b28d95b298b13b13abbe87da8e48ccd1 390 PIRSF PIRSF000429 11 375 8.2E-18 T 12-10-2018 IPR002155 Thiolase GO:0016747 VAPA_1c15880 b28d95b298b13b13abbe87da8e48ccd1 390 Gene3D G3DSA:3.40.47.10 7 386 1.4E-88 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 VAPA_1c15880 b28d95b298b13b13abbe87da8e48ccd1 390 SUPERFAMILY SSF53901 22 233 8.42E-22 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 VAPA_1c41630 e85494c385077c5403bf5c1a37e87fd6 128 SUPERFAMILY SSF54427 7 122 2.47E-23 T 12-10-2018 IPR032710 NTF2-like domain superfamily VAPA_1c41630 e85494c385077c5403bf5c1a37e87fd6 128 Gene3D G3DSA:3.10.450.50 5 123 2.7E-29 T 12-10-2018 VAPA_2c04780 f3674fee85f262d3beaf98c2aa1f8e14 142 SUPERFAMILY SSF52402 2 141 7.62E-33 T 12-10-2018 VAPA_2c04780 f3674fee85f262d3beaf98c2aa1f8e14 142 Pfam PF00582 Universal stress protein family 2 141 1.3E-26 T 12-10-2018 IPR006016 UspA VAPA_2c04780 f3674fee85f262d3beaf98c2aa1f8e14 142 PRINTS PR01438 Universal stress protein signature 101 113 2.0E-12 T 12-10-2018 IPR006015 Universal stress protein A VAPA_2c04780 f3674fee85f262d3beaf98c2aa1f8e14 142 PRINTS PR01438 Universal stress protein signature 119 141 2.0E-12 T 12-10-2018 IPR006015 Universal stress protein A VAPA_2c04780 f3674fee85f262d3beaf98c2aa1f8e14 142 Gene3D G3DSA:3.40.50.620 1 142 2.1E-32 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold VAPA_1c28730 74cbbd694f37767458d8753f0c4c45cb 212 SUPERFAMILY SSF89392 33 192 1.41E-7 T 12-10-2018 IPR029046 Lipoprotein localisation LolA/LolB/LppX VAPA_1c28730 74cbbd694f37767458d8753f0c4c45cb 212 Gene3D G3DSA:2.50.20.10 33 206 3.2E-14 T 12-10-2018 VAPA_2c02230 4c6d71efd4f30146adc3de267595df22 183 SUPERFAMILY SSF117856 32 173 2.33E-17 T 12-10-2018 VAPA_2c02230 4c6d71efd4f30146adc3de267595df22 183 Gene3D G3DSA:3.30.1330.80 27 182 4.4E-12 T 12-10-2018 VAPA_1c07530 3f8708eaf5edc3abf47ae051ad31c4ad 190 Gene3D G3DSA:1.10.260.40 4 76 1.4E-16 T 12-10-2018 VAPA_1c07530 3f8708eaf5edc3abf47ae051ad31c4ad 190 SUPERFAMILY SSF47413 8 70 1.38E-15 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 VAPA_1c07530 3f8708eaf5edc3abf47ae051ad31c4ad 190 SUPERFAMILY SSF51182 60 186 5.15E-21 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily VAPA_1c07530 3f8708eaf5edc3abf47ae051ad31c4ad 190 Gene3D G3DSA:2.60.120.10 85 186 3.5E-15 T 12-10-2018 IPR014710 RmlC-like jelly roll fold VAPA_1c07530 3f8708eaf5edc3abf47ae051ad31c4ad 190 Pfam PF07883 Cupin domain 116 184 1.9E-11 T 12-10-2018 IPR013096 Cupin 2, conserved barrel VAPA_1c07530 3f8708eaf5edc3abf47ae051ad31c4ad 190 SMART SM00530 12 67 1.4E-12 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 VAPA_1c07530 3f8708eaf5edc3abf47ae051ad31c4ad 190 Pfam PF13560 Helix-turn-helix domain 8 64 3.8E-13 T 12-10-2018 VAPA_1c12480 b8583086fb3f6cfd78dd2d644776f7ca 387 Pfam PF10531 SLBB domain 272 321 0.0029 T 12-10-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VAPA_1c12480 b8583086fb3f6cfd78dd2d644776f7ca 387 Pfam PF10531 SLBB domain 190 234 3.8E-7 T 12-10-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 VAPA_1c12480 b8583086fb3f6cfd78dd2d644776f7ca 387 Gene3D G3DSA:3.10.560.10 62 354 1.3E-97 T 12-10-2018 VAPA_1c12480 b8583086fb3f6cfd78dd2d644776f7ca 387 Gene3D G3DSA:3.30.1950.10 96 185 1.3E-97 T 12-10-2018 VAPA_1c12480 b8583086fb3f6cfd78dd2d644776f7ca 387 Pfam PF02563 Polysaccharide biosynthesis/export protein 90 181 1.9E-22 T 12-10-2018 IPR003715 Polysaccharide export protein GO:0015159|GO:0015774|GO:0016020 VAPA_1c12480 b8583086fb3f6cfd78dd2d644776f7ca 387 Gene3D G3DSA:3.10.560.10 74 270 1.3E-97 T 12-10-2018 VAPA_2c03600 247d841b21d99c67831752e6661c4fc0 232 SUPERFAMILY SSF48452 68 201 2.28E-13 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 VAPA_2c03600 247d841b21d99c67831752e6661c4fc0 232 Gene3D G3DSA:1.25.40.10 49 232 1.9E-17 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 VAPA_2c03600 247d841b21d99c67831752e6661c4fc0 232 Pfam PF13181 Tetratricopeptide repeat 156 174 0.043 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 VAPA_2c07970 99ffc7513b6c493c63d230060b86e539 231 Pfam PF03741 Integral membrane protein TerC family 15 183 1.6E-46 T 12-10-2018 IPR005496 Integral membrane protein TerC GO:0016021 VAPA_2c07970 99ffc7513b6c493c63d230060b86e539 231 TIGRFAM TIGR03717 R_switched_YjbE: integral membrane protein, YjbE family 13 185 2.0E-70 T 12-10-2018 IPR022301 Integral membrane protein YjbE VAPA_1c40790 a6d6cdd468d7ad9687ff87c71b09f19d 418 Pfam PF06500 Alpha/beta hydrolase of unknown function (DUF1100) 97 305 1.4E-8 T 12-10-2018 IPR010520 UPF0255 family VAPA_1c40790 a6d6cdd468d7ad9687ff87c71b09f19d 418 SUPERFAMILY SSF53474 62 415 9.25E-37 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c40790 a6d6cdd468d7ad9687ff87c71b09f19d 418 Gene3D G3DSA:3.40.50.1820 63 415 6.3E-51 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_2c06490 ef632de885d94c59389f3b52d8a56154 121 Pfam PF13670 Peptidase propeptide and YPEB domain 11 89 2.0E-24 T 12-10-2018 IPR025711 PepSY domain VAPA_2c10870 ecbda9557c37aa4b18f9020306239975 84 Pfam PF11666 Protein of unknown function (DUF2933) 23 69 3.1E-22 T 12-10-2018 IPR021682 Protein of unknown function DUF2933 VAPA_1c03840 200bc632c97e1a3492cbbef9107f98fd 137 Pfam PF00076 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 5 74 3.2E-22 T 12-10-2018 IPR000504 RNA recognition motif domain GO:0003676 VAPA_1c03840 200bc632c97e1a3492cbbef9107f98fd 137 SUPERFAMILY SSF54928 3 112 3.72E-36 T 12-10-2018 IPR035979 RNA-binding domain superfamily GO:0003676 VAPA_1c03840 200bc632c97e1a3492cbbef9107f98fd 137 Gene3D G3DSA:3.30.70.330 1 100 1.2E-30 T 12-10-2018 IPR012677 Nucleotide-binding alpha-beta plait domain superfamily VAPA_1c03840 200bc632c97e1a3492cbbef9107f98fd 137 SMART SM00360 4 77 3.3E-29 T 12-10-2018 IPR000504 RNA recognition motif domain GO:0003676 VAPA_2c02240 973b16c08ab3805f123149d326237aaf 132 SUPERFAMILY SSF117856 8 125 4.71E-18 T 12-10-2018 VAPA_2c02240 973b16c08ab3805f123149d326237aaf 132 Gene3D G3DSA:3.30.1330.80 7 129 2.5E-12 T 12-10-2018 VAPA_2c02240 973b16c08ab3805f123149d326237aaf 132 Pfam PF03479 Domain of unknown function (DUF296) 15 125 8.6E-11 T 12-10-2018 IPR005175 PPC domain VAPA_1c19300 6e86da31071c7a29821a4e614937bbfc 292 Pfam PF02653 Branched-chain amino acid transport system / permease component 13 276 2.9E-33 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 VAPA_1c10880 c119a1698c4253c0d8eb4fedcf4c29f0 183 SUPERFAMILY SSF55729 22 177 4.05E-28 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase VAPA_1c10880 c119a1698c4253c0d8eb4fedcf4c29f0 183 Gene3D G3DSA:3.40.630.30 17 180 1.7E-47 T 12-10-2018 VAPA_1c10880 c119a1698c4253c0d8eb4fedcf4c29f0 183 Pfam PF00583 Acetyltransferase (GNAT) family 65 151 9.0E-13 T 12-10-2018 IPR000182 GNAT domain VAPA_1c45060 f5dd460e8cdc3fa2789a663bd678cbde 559 Gene3D G3DSA:3.40.50.300 2 265 3.0E-41 T 12-10-2018 VAPA_1c45060 f5dd460e8cdc3fa2789a663bd678cbde 559 Gene3D G3DSA:3.40.50.300 266 552 4.4E-55 T 12-10-2018 VAPA_1c45060 f5dd460e8cdc3fa2789a663bd678cbde 559 TIGRFAM TIGR00634 recN: DNA repair protein RecN 3 551 8.0E-142 T 12-10-2018 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 VAPA_1c45060 f5dd460e8cdc3fa2789a663bd678cbde 559 PIRSF PIRSF003128 2 557 1.4E-149 T 12-10-2018 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 VAPA_1c45060 f5dd460e8cdc3fa2789a663bd678cbde 559 SUPERFAMILY SSF52540 1 505 1.35E-62 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c45060 f5dd460e8cdc3fa2789a663bd678cbde 559 Pfam PF02463 RecF/RecN/SMC N terminal domain 3 504 1.1E-16 T 12-10-2018 IPR003395 RecF/RecN/SMC, N-terminal VAPA_1c23800 f55ed951202d7a8beb54eb97071ac565 184 Pfam PF01814 Hemerythrin HHE cation binding domain 8 139 3.3E-10 T 12-10-2018 IPR012312 Haemerythrin-like Reactome: R-HSA-390471|Reactome: R-HSA-8951664|Reactome: R-HSA-917937|Reactome: R-HSA-983168 VAPA_1c23800 f55ed951202d7a8beb54eb97071ac565 184 Gene3D G3DSA:1.20.120.520 3 161 1.0E-12 T 12-10-2018 VAPA_1c36890 caf474c452fc629cf121b0857823ce59 423 Pfam PF04235 Protein of unknown function (DUF418) 243 402 2.0E-42 T 12-10-2018 IPR007349 Domain of unknown function DUF418 VAPA_1c26340 81698069330d5a937975328a18edc6fb 100 Pfam PF07876 Stress responsive A/B Barrel Domain 2 99 5.6E-18 T 12-10-2018 IPR013097 Stress responsive alpha-beta barrel VAPA_1c26340 81698069330d5a937975328a18edc6fb 100 Gene3D G3DSA:3.30.70.100 1 99 2.5E-19 T 12-10-2018 VAPA_1c26340 81698069330d5a937975328a18edc6fb 100 SMART SM00886 2 100 1.8E-24 T 12-10-2018 IPR013097 Stress responsive alpha-beta barrel VAPA_1c26340 81698069330d5a937975328a18edc6fb 100 SUPERFAMILY SSF54909 1 99 6.6E-20 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel VAPA_2c04600 8bd52f3b7b0bcb5e67399fd1530abe2e 221 Gene3D G3DSA:1.20.120.520 2 167 3.9E-24 T 12-10-2018 VAPA_2c04600 8bd52f3b7b0bcb5e67399fd1530abe2e 221 Pfam PF01814 Hemerythrin HHE cation binding domain 8 146 1.4E-13 T 12-10-2018 IPR012312 Haemerythrin-like Reactome: R-HSA-390471|Reactome: R-HSA-8951664|Reactome: R-HSA-917937|Reactome: R-HSA-983168 VAPA_1c31720 0b7e7b5f5467556676f2fea399d2d460 228 Pfam PF14341 PilX N-terminal 15 64 6.4E-8 T 12-10-2018 IPR025746 Type 4 fimbrial biogenesis protein PilX, N-terminal domain VAPA_1c31720 0b7e7b5f5467556676f2fea399d2d460 228 Pfam PF13681 Type IV pilus assembly protein PilX C-term 124 219 4.2E-7 T 12-10-2018 IPR025205 PilX/PilW C-terminal domain VAPA_1c24630 b7f8e7ac2b0f423bee50173064f07e35 110 Gene3D G3DSA:3.40.30.10 1 109 9.4E-36 T 12-10-2018 VAPA_1c24630 b7f8e7ac2b0f423bee50173064f07e35 110 SUPERFAMILY SSF52833 6 109 3.96E-40 T 12-10-2018 IPR036249 Thioredoxin-like superfamily VAPA_1c24630 b7f8e7ac2b0f423bee50173064f07e35 110 PIRSF PIRSF000077 3 109 2.6E-44 T 12-10-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 VAPA_1c24630 b7f8e7ac2b0f423bee50173064f07e35 110 ProSitePatterns PS00194 Thioredoxin family active site. 26 44 - T 12-10-2018 IPR017937 Thioredoxin, conserved site GO:0045454 VAPA_1c24630 b7f8e7ac2b0f423bee50173064f07e35 110 PRINTS PR00421 Thioredoxin family signature 33 42 8.0E-10 T 12-10-2018 VAPA_1c24630 b7f8e7ac2b0f423bee50173064f07e35 110 PRINTS PR00421 Thioredoxin family signature 73 84 8.0E-10 T 12-10-2018 VAPA_1c24630 b7f8e7ac2b0f423bee50173064f07e35 110 PRINTS PR00421 Thioredoxin family signature 25 33 8.0E-10 T 12-10-2018 VAPA_1c24630 b7f8e7ac2b0f423bee50173064f07e35 110 TIGRFAM TIGR01068 thioredoxin: thioredoxin 10 108 6.4E-40 T 12-10-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 VAPA_1c24630 b7f8e7ac2b0f423bee50173064f07e35 110 Pfam PF00085 Thioredoxin 7 107 1.6E-34 T 12-10-2018 IPR013766 Thioredoxin domain GO:0045454 VAPA_1c32640 b3fcc641cad5a55f0cb9459bc20b253e 273 SUPERFAMILY SSF47240 5 177 2.0E-35 T 12-10-2018 IPR009078 Ferritin-like superfamily VAPA_1c32640 b3fcc641cad5a55f0cb9459bc20b253e 273 Gene3D G3DSA:1.10.620.20 8 194 9.7E-19 T 12-10-2018 IPR012348 Ribonucleotide reductase-like GO:0016491|GO:0055114 Reactome: R-HSA-499943 VAPA_1c16500 ee70f0730d673fec384e630f06f5ff07 311 Gene3D G3DSA:1.10.3720.10 83 304 6.2E-22 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c16500 ee70f0730d673fec384e630f06f5ff07 311 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 112 310 2.3E-36 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 VAPA_1c16500 ee70f0730d673fec384e630f06f5ff07 311 SUPERFAMILY SSF161098 90 295 2.49E-17 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c27790 9a52fd45898e23bbbc5c62ef6363b721 302 Gene3D G3DSA:1.10.620.20 13 229 1.6E-10 T 12-10-2018 IPR012348 Ribonucleotide reductase-like GO:0016491|GO:0055114 Reactome: R-HSA-499943 VAPA_1c27790 9a52fd45898e23bbbc5c62ef6363b721 302 SUPERFAMILY SSF47240 18 215 2.56E-19 T 12-10-2018 IPR009078 Ferritin-like superfamily VAPA_1c00210 89123d9386b42499e0bc267ad16a50bd 310 Pfam PF09721 Transmembrane exosortase (Exosortase_EpsH) 30 279 3.7E-23 T 12-10-2018 IPR019127 Exosortase VAPA_1c00210 89123d9386b42499e0bc267ad16a50bd 310 TIGRFAM TIGR04178 exo_archaeo: exosortase/archaeosortase family protein 191 277 4.4E-12 T 12-10-2018 IPR026392 Exosortase/Archaeosortase domain VAPA_1c08210 e3cd897985f37706b20b50e1949b994c 263 SUPERFAMILY SSF53335 28 151 8.22E-13 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase VAPA_1c08210 e3cd897985f37706b20b50e1949b994c 263 Gene3D G3DSA:3.40.50.150 19 230 2.3E-30 T 12-10-2018 VAPA_1c01700 ec04554cbe2e991d22d9ea47f874978a 286 Pfam PF02653 Branched-chain amino acid transport system / permease component 5 272 7.4E-35 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 VAPA_2c12420 9f90a79ce77a00614b4fe6e363e90370 199 SUPERFAMILY SSF46689 13 90 2.59E-15 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 VAPA_2c12420 9f90a79ce77a00614b4fe6e363e90370 199 Gene3D G3DSA:1.10.10.60 14 60 6.0E-19 T 12-10-2018 VAPA_2c12420 9f90a79ce77a00614b4fe6e363e90370 199 SUPERFAMILY SSF48498 92 196 1.83E-23 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily VAPA_2c12420 9f90a79ce77a00614b4fe6e363e90370 199 Pfam PF00440 Bacterial regulatory proteins, tetR family 24 70 8.6E-14 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 VAPA_2c12420 9f90a79ce77a00614b4fe6e363e90370 199 Gene3D G3DSA:1.10.357.10 62 196 1.8E-31 T 12-10-2018 VAPA_2c12420 9f90a79ce77a00614b4fe6e363e90370 199 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 45 68 4.5E-7 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 VAPA_2c12420 9f90a79ce77a00614b4fe6e363e90370 199 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 24 37 4.5E-7 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 VAPA_1c21960 00eda3aac904a931652cfa8866c7b2df 112 SUPERFAMILY SSF54909 1 103 3.51E-13 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel VAPA_1c21960 00eda3aac904a931652cfa8866c7b2df 112 Gene3D G3DSA:3.30.70.100 12 106 3.6E-7 T 12-10-2018 VAPA_1c18390 5618f9f3a8e2d0fccd6022b2c8973682 565 Gene3D G3DSA:3.40.50.1820 125 342 2.5E-7 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c18390 5618f9f3a8e2d0fccd6022b2c8973682 565 Pfam PF07519 Tannase and feruloyl esterase 94 563 1.0E-140 T 12-10-2018 IPR011118 Tannase/feruloyl esterase MetaCyc: PWY-6784 VAPA_1c18390 5618f9f3a8e2d0fccd6022b2c8973682 565 SUPERFAMILY SSF53474 148 295 9.91E-11 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c28700 ce1c6d7ba4ff6604e3c06914d600b4a0 254 Gene3D G3DSA:3.40.50.150 23 252 1.1E-19 T 12-10-2018 VAPA_1c28700 ce1c6d7ba4ff6604e3c06914d600b4a0 254 SUPERFAMILY SSF53335 43 235 7.99E-21 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase VAPA_1c28700 ce1c6d7ba4ff6604e3c06914d600b4a0 254 Pfam PF08241 Methyltransferase domain 62 170 7.2E-9 T 12-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 VAPA_1c08890 f0b0c1ed81ae1a2d206c7c2c7951f0b2 243 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 24 123 2.5E-18 T 12-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 VAPA_1c08890 f0b0c1ed81ae1a2d206c7c2c7951f0b2 243 Gene3D G3DSA:1.10.3720.10 17 230 3.3E-43 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c08890 f0b0c1ed81ae1a2d206c7c2c7951f0b2 243 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 47 229 3.1E-12 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 VAPA_1c08890 f0b0c1ed81ae1a2d206c7c2c7951f0b2 243 SUPERFAMILY SSF161098 22 214 1.44E-37 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c55030 068f960a8c9d037b1a01f74b4649d3f9 211 Pfam PF06835 Lipopolysaccharide-assembly, LptC-related 22 200 1.1E-26 T 12-10-2018 IPR010664 Lipopolysaccharide assembly, LptC-related VAPA_1c55030 068f960a8c9d037b1a01f74b4649d3f9 211 TIGRFAM TIGR04409 LptC_YrbK: LPS export ABC transporter periplasmic protein LptC 17 201 1.0E-44 T 12-10-2018 IPR026265 Lipopolysaccharide export system protein LptC GO:0005887|GO:0015221|GO:0015920 VAPA_1c01070 f9f445165e5ab812c176c52ca93871ab 268 Pfam PF04199 Putative cyclase 6 190 4.7E-34 T 12-10-2018 IPR007325 Kynurenine formamidase/cyclase-like GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 VAPA_1c01070 f9f445165e5ab812c176c52ca93871ab 268 SUPERFAMILY SSF102198 2 260 1.57E-55 T 12-10-2018 IPR037175 Kynurenine formamidase superfamily GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 VAPA_1c01070 f9f445165e5ab812c176c52ca93871ab 268 Gene3D G3DSA:3.50.30.50 3 262 1.7E-46 T 12-10-2018 IPR037175 Kynurenine formamidase superfamily GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 VAPA_1c19480 157e5963a3913c52bb69f0dd87153bf0 363 Pfam PF06224 Winged helix DNA-binding domain 28 359 2.6E-54 T 12-10-2018 IPR009351 Protein of unknown function DUF1006 VAPA_2c13270 caf940f9697c3aa88fcb588188d8e806 349 Pfam PF04610 TrbL/VirB6 plasmid conjugal transfer protein 37 251 6.8E-41 T 12-10-2018 IPR007688 Plasmid conjugal transfer TrbL/VirB6 GO:0030255 VAPA_2c05970 afbea37e5c542081c0507fa5b9a8a71f 596 SUPERFAMILY SSF53474 170 528 1.31E-14 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_2c05970 afbea37e5c542081c0507fa5b9a8a71f 596 Gene3D G3DSA:3.40.50.1820 144 335 9.5E-6 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_2c05970 afbea37e5c542081c0507fa5b9a8a71f 596 Pfam PF07519 Tannase and feruloyl esterase 108 596 1.3E-127 T 12-10-2018 IPR011118 Tannase/feruloyl esterase MetaCyc: PWY-6784 VAPA_1c18650 55c4be0221190129ba4d34bf02221396 259 Gene3D G3DSA:3.90.226.10 1 203 7.9E-72 T 12-10-2018 VAPA_1c18650 55c4be0221190129ba4d34bf02221396 259 Pfam PF00378 Enoyl-CoA hydratase/isomerase 13 233 1.5E-37 T 12-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 VAPA_1c18650 55c4be0221190129ba4d34bf02221396 259 SUPERFAMILY SSF52096 4 241 1.84E-65 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily VAPA_1c18650 55c4be0221190129ba4d34bf02221396 259 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 102 122 - T 12-10-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824 VAPA_1c42430 5531605c7c80e6cdcdbefde6b9059843 175 Pfam PF13340 Putative transposase of IS4/5 family (DUF4096) 3 73 5.3E-22 T 12-10-2018 IPR025161 Putative transposase IS4/IS5 family VAPA_2c09780 fe33d079ecad2f38854b9390418c977f 91 Gene3D G3DSA:3.10.129.10 1 88 2.3E-9 T 12-10-2018 VAPA_2c09780 fe33d079ecad2f38854b9390418c977f 91 SUPERFAMILY SSF54637 2 76 8.97E-9 T 12-10-2018 IPR029069 HotDog domain superfamily VAPA_1c23760 39aec9e3b37ace24c58391419f268819 62 Pfam PF09838 Uncharacterized protein conserved in bacteria (DUF2065) 6 61 4.2E-22 T 12-10-2018 IPR019201 Protein of unknown function DUF2065 VAPA_2c05610 03dae0ba6ffce9b7af3cce628bc9c7db 363 Pfam PF00296 Luciferase-like monooxygenase 1 302 1.9E-56 T 12-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 VAPA_2c05610 03dae0ba6ffce9b7af3cce628bc9c7db 363 Gene3D G3DSA:3.20.20.30 1 346 2.2E-81 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 VAPA_2c05610 03dae0ba6ffce9b7af3cce628bc9c7db 363 SUPERFAMILY SSF51679 1 343 1.41E-70 T 12-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 VAPA_2c10050 4ba78d081cdf2d4b2377907cdb88ea03 264 SUPERFAMILY SSF47616 101 218 1.36E-7 T 12-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily VAPA_2c10050 4ba78d081cdf2d4b2377907cdb88ea03 264 Gene3D G3DSA:3.40.30.10 32 102 1.1E-6 T 12-10-2018 VAPA_2c10050 4ba78d081cdf2d4b2377907cdb88ea03 264 Gene3D G3DSA:1.20.1050.10 103 214 1.1E-6 T 12-10-2018 VAPA_2c10050 4ba78d081cdf2d4b2377907cdb88ea03 264 SUPERFAMILY SSF52833 28 122 2.85E-9 T 12-10-2018 IPR036249 Thioredoxin-like superfamily VAPA_1c43550 819054c315d59a99f9d95da27068b529 138 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 92 134 1.6E-14 T 12-10-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain VAPA_1c43550 819054c315d59a99f9d95da27068b529 138 Pfam PF00460 Flagella basal body rod protein 11 40 3.9E-9 T 12-10-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 VAPA_1c43550 819054c315d59a99f9d95da27068b529 138 TIGRFAM TIGR01395 FlgC: flagellar basal-body rod protein FlgC 9 138 9.6E-52 T 12-10-2018 IPR006299 Flagellar basal-body rod protein FlgC GO:0030694|GO:0071973 VAPA_1c43550 819054c315d59a99f9d95da27068b529 138 ProSitePatterns PS00588 Flagella basal body rod proteins signature. 17 37 - T 12-10-2018 IPR019776 Flagellar basal body rod protein, conserved site VAPA_1c18180 c612c8f5e57086a468dddef9709f6d46 150 Pfam PF14534 Domain of unknown function (DUF4440) 34 140 4.6E-17 T 12-10-2018 IPR027843 Domain of unknown function DUF4440 VAPA_1c18180 c612c8f5e57086a468dddef9709f6d46 150 Gene3D G3DSA:3.10.450.50 27 148 3.1E-26 T 12-10-2018 VAPA_1c18180 c612c8f5e57086a468dddef9709f6d46 150 SUPERFAMILY SSF54427 30 145 6.38E-24 T 12-10-2018 IPR032710 NTF2-like domain superfamily VAPA_1c42850 0e7780fe4301be1ca5f76f3e7a24c40f 137 Gene3D G3DSA:3.30.2020.30 4 103 1.3E-27 T 12-10-2018 IPR038492 GBBH-like, N-terminal domain superfamily Reactome: R-HSA-71262 VAPA_1c42850 0e7780fe4301be1ca5f76f3e7a24c40f 137 Pfam PF06155 Protein of unknown function (DUF971) 14 98 1.2E-26 T 12-10-2018 IPR010376 Gamma-butyrobetaine hydroxylase-like, N-terminal Reactome: R-HSA-71262 VAPA_1c07240 df948f7a851d8f3b998d8b39c89b9fbc 130 Pfam PF13366 PD-(D/E)XK nuclease superfamily 10 125 2.8E-33 T 12-10-2018 IPR026350 GxxExxY protein VAPA_1c07240 df948f7a851d8f3b998d8b39c89b9fbc 130 TIGRFAM TIGR04256 GxxExxY: GxxExxY protein 11 127 2.2E-37 T 12-10-2018 IPR026350 GxxExxY protein VAPA_1c17790 dd232db0b3c957577dbb5f4ee7652f61 141 Pfam PF04134 Protein of unknown function, DUF393 11 116 1.9E-17 T 12-10-2018 IPR007263 Protein of unknown function DUF393 VAPA_1c31500 7c3e237a6212c9e272b8f142b8a9ba67 138 Pfam PF08388 Group II intron, maturase-specific domain 31 85 2.9E-10 T 12-10-2018 IPR013597 Group II intron, maturase-specific VAPA_1c40370 bf731765167fd7f33f11be91deb53428 540 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 15 214 5.1E-9 T 12-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 VAPA_1c23260 0df85deeb3a72e670df758606e7cbfb0 1235 SUPERFAMILY SSF110296 87 353 2.62E-5 T 12-10-2018 VAPA_1c11410 86a66910b71f776ec1df0462987995fb 209 SUPERFAMILY SSF47240 48 123 4.25E-15 T 12-10-2018 IPR009078 Ferritin-like superfamily VAPA_1c11410 86a66910b71f776ec1df0462987995fb 209 Hamap MF_01658 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase [coq7]. 9 209 31.202 T 12-10-2018 IPR011566 Ubiquinone biosynthesis protein Coq7 GO:0006744|GO:0055114 Reactome: R-HSA-2142789 VAPA_1c11410 86a66910b71f776ec1df0462987995fb 209 Pfam PF03232 Ubiquinone biosynthesis protein COQ7 50 207 1.2E-41 T 12-10-2018 IPR011566 Ubiquinone biosynthesis protein Coq7 GO:0006744|GO:0055114 Reactome: R-HSA-2142789 VAPA_1c12540 61d3cddfb0749c7b532f5ce26675a0f9 425 SUPERFAMILY SSF51445 51 338 2.68E-22 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily VAPA_1c12540 61d3cddfb0749c7b532f5ce26675a0f9 425 Gene3D G3DSA:3.20.20.80 56 337 4.3E-21 T 12-10-2018 VAPA_2c01650 e71ed0025cadaf50433dc56c1e24db9b 180 SUPERFAMILY SSF52540 2 135 1.21E-17 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_2c01650 e71ed0025cadaf50433dc56c1e24db9b 180 Gene3D G3DSA:3.40.50.300 1 163 2.9E-26 T 12-10-2018 VAPA_2c01650 e71ed0025cadaf50433dc56c1e24db9b 180 Pfam PF13671 AAA domain 2 116 4.4E-10 T 12-10-2018 VAPA_1c43000 b192f5ed40c76fee05f0a78be66fb5eb 426 SUPERFAMILY SSF103473 18 421 1.57E-56 T 12-10-2018 IPR036259 MFS transporter superfamily VAPA_1c43000 b192f5ed40c76fee05f0a78be66fb5eb 426 Gene3D G3DSA:1.20.1250.20 15 239 4.0E-23 T 12-10-2018 VAPA_1c43000 b192f5ed40c76fee05f0a78be66fb5eb 426 ProSitePatterns PS00216 Sugar transport proteins signature 1. 69 85 - T 12-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 VAPA_1c43000 b192f5ed40c76fee05f0a78be66fb5eb 426 Gene3D G3DSA:1.20.1250.20 240 421 6.4E-24 T 12-10-2018 VAPA_1c43000 b192f5ed40c76fee05f0a78be66fb5eb 426 Pfam PF07690 Major Facilitator Superfamily 19 200 3.9E-19 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 VAPA_1c43000 b192f5ed40c76fee05f0a78be66fb5eb 426 Pfam PF07690 Major Facilitator Superfamily 254 420 5.1E-18 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 VAPA_1c03620 7b855577a15a4078fa9d1db696b8ec31 323 Pfam PF02470 MlaD protein 44 113 1.1E-14 T 12-10-2018 IPR003399 Mce/MlaD VAPA_2c01850 1c64f892afe7a85210b3847d1f2b81b9 189 SMART SM00903 20 172 7.6E-21 T 12-10-2018 IPR002563 Flavin reductase like domain GO:0010181 VAPA_2c01850 1c64f892afe7a85210b3847d1f2b81b9 189 SUPERFAMILY SSF50475 8 177 9.81E-43 T 12-10-2018 VAPA_2c01850 1c64f892afe7a85210b3847d1f2b81b9 189 Gene3D G3DSA:2.30.110.10 9 182 9.4E-51 T 12-10-2018 IPR012349 FMN-binding split barrel GO:0048037 VAPA_2c01850 1c64f892afe7a85210b3847d1f2b81b9 189 Pfam PF01613 Flavin reductase like domain 24 165 3.5E-23 T 12-10-2018 IPR002563 Flavin reductase like domain GO:0010181 VAPA_1c51350 153524239e65888a4ccd6f4827e147bc 688 Gene3D G3DSA:3.30.1490.20 368 555 9.6E-41 T 12-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 VAPA_1c51350 153524239e65888a4ccd6f4827e147bc 688 SUPERFAMILY SSF56059 372 683 5.89E-51 T 12-10-2018 VAPA_1c51350 153524239e65888a4ccd6f4827e147bc 688 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 386 684 3.5E-45 T 12-10-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 VAPA_1c51350 153524239e65888a4ccd6f4827e147bc 688 Gene3D G3DSA:3.30.470.20 556 684 1.1E-19 T 12-10-2018 VAPA_1c23970 0349034e358558cc4bf581dc0c64b050 149 Pfam PF07452 CHRD domain 36 144 5.4E-29 T 12-10-2018 IPR010895 CHRD VAPA_1c23970 0349034e358558cc4bf581dc0c64b050 149 SMART SM00754 33 147 3.0E-33 T 12-10-2018 IPR010895 CHRD VAPA_2c04160 54c0b0fa23397c79d8e0b3f6d759e57b 327 SUPERFAMILY SSF52518 4 323 5.54E-93 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold VAPA_2c04160 54c0b0fa23397c79d8e0b3f6d759e57b 327 Pfam PF00676 Dehydrogenase E1 component 14 309 1.5E-78 T 12-10-2018 IPR001017 Dehydrogenase, E1 component GO:0016624 Reactome: R-HSA-389661 VAPA_2c04160 54c0b0fa23397c79d8e0b3f6d759e57b 327 Gene3D G3DSA:3.40.50.970 1 327 1.9E-112 T 12-10-2018 VAPA_1c51110 14d3e5ea6f010fd0326e22329f02277d 302 Gene3D G3DSA:3.40.190.10 92 289 4.1E-59 T 12-10-2018 VAPA_1c51110 14d3e5ea6f010fd0326e22329f02277d 302 SUPERFAMILY SSF46785 3 112 3.01E-23 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily VAPA_1c51110 14d3e5ea6f010fd0326e22329f02277d 302 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 63 4.0E-21 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 VAPA_1c51110 14d3e5ea6f010fd0326e22329f02277d 302 SUPERFAMILY SSF53850 89 293 7.42E-44 T 12-10-2018 VAPA_1c51110 14d3e5ea6f010fd0326e22329f02277d 302 Gene3D G3DSA:1.10.10.10 3 89 1.9E-25 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VAPA_1c51110 14d3e5ea6f010fd0326e22329f02277d 302 Gene3D G3DSA:3.40.190.10 163 263 4.1E-59 T 12-10-2018 VAPA_1c51110 14d3e5ea6f010fd0326e22329f02277d 302 Pfam PF03466 LysR substrate binding domain 88 291 8.3E-40 T 12-10-2018 IPR005119 LysR, substrate-binding VAPA_1c34390 e34050b7a07cb52d4398939adb1e20fc 183 SUPERFAMILY SSF51182 24 150 2.67E-12 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily VAPA_1c34390 e34050b7a07cb52d4398939adb1e20fc 183 Gene3D G3DSA:2.60.120.10 31 179 1.4E-10 T 12-10-2018 IPR014710 RmlC-like jelly roll fold VAPA_1c54950 b1e7b6692d8f4331849b9bc3f43b2639 172 Pfam PF04519 Polymer-forming cytoskeletal 65 160 5.4E-18 T 12-10-2018 IPR007607 Bactofilin A/B VAPA_2c11000 2cb3c30fd5d3ee957783bc4794e53d49 60 Pfam PF12244 Protein of unknown function (DUF3606) 4 56 1.4E-18 T 12-10-2018 IPR022037 Protein of unknown function DUF3606 VAPA_2c01340 a8ee2f6caf6796029c6b6fbfd1fc1bb3 174 SUPERFAMILY SSF55729 27 171 1.13E-28 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase VAPA_2c01340 a8ee2f6caf6796029c6b6fbfd1fc1bb3 174 Pfam PF00583 Acetyltransferase (GNAT) family 57 157 3.6E-12 T 12-10-2018 IPR000182 GNAT domain VAPA_2c01340 a8ee2f6caf6796029c6b6fbfd1fc1bb3 174 Gene3D G3DSA:3.40.630.30 26 163 2.1E-31 T 12-10-2018 VAPA_1c34650 c1e7cf4459ae81b0675e7a04a7ee2beb 370 Pfam PF01757 Acyltransferase family 4 342 3.9E-19 T 12-10-2018 IPR002656 Acyltransferase 3 GO:0016747 VAPA_1c15860 cdad1e27d11b355a19419e14a843b928 162 SUPERFAMILY SSF54427 6 161 5.36E-38 T 12-10-2018 IPR032710 NTF2-like domain superfamily VAPA_1c15860 cdad1e27d11b355a19419e14a843b928 162 Pfam PF00866 Ring hydroxylating beta subunit 18 150 1.2E-21 T 12-10-2018 IPR000391 Ring-hydroxylating dioxygenase beta subunit GO:0006725|GO:0055114 VAPA_1c15860 cdad1e27d11b355a19419e14a843b928 162 Gene3D G3DSA:3.10.450.50 1 162 7.4E-37 T 12-10-2018 VAPA_1c45450 6316526bb7fc9dbe6a1ca5b7027452ca 448 SUPERFAMILY SSF63411 268 446 1.3E-45 T 12-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 VAPA_1c45450 6316526bb7fc9dbe6a1ca5b7027452ca 448 Gene3D G3DSA:3.30.830.10 32 247 2.7E-43 T 12-10-2018 VAPA_1c45450 6316526bb7fc9dbe6a1ca5b7027452ca 448 Gene3D G3DSA:3.30.830.10 258 448 1.9E-55 T 12-10-2018 VAPA_1c45450 6316526bb7fc9dbe6a1ca5b7027452ca 448 SUPERFAMILY SSF63411 29 241 4.37E-34 T 12-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 VAPA_1c45450 6316526bb7fc9dbe6a1ca5b7027452ca 448 Pfam PF05193 Peptidase M16 inactive domain 205 381 1.2E-30 T 12-10-2018 IPR007863 Peptidase M16, C-terminal VAPA_1c10470 b17bf14642281ff54c07e392a377b2a8 205 SUPERFAMILY SSF100950 17 203 1.53E-40 T 12-10-2018 IPR037171 NagB/RpiA transferase-like VAPA_1c10470 b17bf14642281ff54c07e392a377b2a8 205 Gene3D G3DSA:3.40.50.10420 15 204 2.7E-35 T 12-10-2018 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain superfamily VAPA_1c10470 b17bf14642281ff54c07e392a377b2a8 205 Pfam PF01812 5-formyltetrahydrofolate cyclo-ligase family 17 195 6.3E-22 T 12-10-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase VAPA_1c10470 b17bf14642281ff54c07e392a377b2a8 205 PIRSF PIRSF006806 13 200 2.8E-24 T 12-10-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase VAPA_1c10470 b17bf14642281ff54c07e392a377b2a8 205 TIGRFAM TIGR02727 MTHFS_bact: 5-formyltetrahydrofolate cyclo-ligase 17 195 1.8E-33 T 12-10-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase VAPA_1c14450 8666c4a44e18d67233f50acddb5f0eb9 380 Pfam PF10129 OpgC protein 3 361 1.7E-76 T 12-10-2018 IPR014550 Uncharacterised conserved protein UCP028704, OpgC VAPA_1c14450 8666c4a44e18d67233f50acddb5f0eb9 380 PIRSF PIRSF028704 1 363 4.8E-50 T 12-10-2018 IPR014550 Uncharacterised conserved protein UCP028704, OpgC VAPA_2c11790 41980f7d7339e7c1d8b52a7f3f6c1ef5 118 Pfam PF13356 Arm DNA-binding domain 4 86 4.5E-17 T 12-10-2018 IPR025166 Integrase, DNA-binding domain VAPA_2c11790 41980f7d7339e7c1d8b52a7f3f6c1ef5 118 Gene3D G3DSA:3.30.160.390 2 102 3.5E-27 T 12-10-2018 IPR038488 Integrase, DNA-binding domain superfamily VAPA_1c25730 9794b3210290d8a86060483c1bfb781b 194 SUPERFAMILY SSF52218 3 167 2.95E-32 T 12-10-2018 IPR029039 Flavoprotein-like superfamily VAPA_1c25730 9794b3210290d8a86060483c1bfb781b 194 TIGRFAM TIGR03567 FMN_reduc_SsuE: FMN reductase 3 170 3.2E-69 T 12-10-2018 IPR020048 NADPH-dependent FMN reductase, SsuE GO:0008752|GO:0046306|GO:0055114 KEGG: 00740+1.5.1.38|MetaCyc: PWY-7723 VAPA_1c25730 9794b3210290d8a86060483c1bfb781b 194 Gene3D G3DSA:3.40.50.360 1 178 2.8E-47 T 12-10-2018 IPR029039 Flavoprotein-like superfamily VAPA_1c25730 9794b3210290d8a86060483c1bfb781b 194 Pfam PF03358 NADPH-dependent FMN reductase 2 142 9.1E-31 T 12-10-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 VAPA_2c10400 bdd84aff1b5b36d232f0cf6440fe04b0 324 Pfam PF02653 Branched-chain amino acid transport system / permease component 24 266 2.1E-38 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 VAPA_2c02750 2146252b8e3bd7672f1c913aa914e39e 492 SUPERFAMILY SSF75304 6 480 4.84E-127 T 12-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 VAPA_2c02750 2146252b8e3bd7672f1c913aa914e39e 492 Pfam PF01425 Amidase 42 471 1.2E-97 T 12-10-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 VAPA_2c02750 2146252b8e3bd7672f1c913aa914e39e 492 Gene3D G3DSA:3.90.1300.10 17 489 7.6E-134 T 12-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 VAPA_1c06120 7a8007dcce5e80fcacdf0bda686cd926 131 Pfam PF13665 Domain of unknown function (DUF4150) 10 116 9.3E-41 T 12-10-2018 IPR025425 Domain of unknown function DUF4150 VAPA_1c51330 91d0887b16ed1220af4cce02f89e0323 206 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 27 158 7.9E-24 T 12-10-2018 IPR007387 TRAP transporter, small membrane protein DctQ VAPA_1c47330 f1590571c2fc92d30b8c254288270131 547 SMART SM00974 457 537 7.7E-13 T 12-10-2018 IPR018306 Bacteriophage T5, Orf172 DNA-binding VAPA_1c47330 f1590571c2fc92d30b8c254288270131 547 Pfam PF10544 T5orf172 domain 448 537 5.0E-13 T 12-10-2018 IPR018306 Bacteriophage T5, Orf172 DNA-binding VAPA_1c07140 a0d64cdbdaa6e680a46a4659e77c0295 252 Hamap MF_00943 Maleate isomerase [maiA]. 7 252 49.765 T 12-10-2018 IPR028615 Maleate isomerase GO:0050076 KEGG: 00650+5.2.1.1|KEGG: 00760+5.2.1.1|MetaCyc: PWY-5033|MetaCyc: PWY-6993|MetaCyc: PWY-7128|MetaCyc: PWY-722 VAPA_1c07140 a0d64cdbdaa6e680a46a4659e77c0295 252 Gene3D G3DSA:3.40.50.12500 7 252 8.9E-88 T 12-10-2018 VAPA_1c07140 a0d64cdbdaa6e680a46a4659e77c0295 252 Pfam PF01177 Asp/Glu/Hydantoin racemase 9 231 1.2E-8 T 12-10-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 VAPA_1c07140 a0d64cdbdaa6e680a46a4659e77c0295 252 PIRSF PIRSF015736 1 252 6.4E-64 T 12-10-2018 IPR026286 Maleate isomerase/Arylmalonate decarboxylase VAPA_1c13820 c3c9c2f34298498b4edbfd661fbee959 335 PIRSF PIRSF017082 8 333 4.9E-68 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c13820 c3c9c2f34298498b4edbfd661fbee959 335 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 58 329 1.0E-63 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c13820 c3c9c2f34298498b4edbfd661fbee959 335 Gene3D G3DSA:3.40.190.150 39 323 2.3E-91 T 12-10-2018 VAPA_1c13820 c3c9c2f34298498b4edbfd661fbee959 335 Gene3D G3DSA:3.40.190.10 136 258 2.3E-91 T 12-10-2018 VAPA_1c13820 c3c9c2f34298498b4edbfd661fbee959 335 SUPERFAMILY SSF53850 126 290 2.29E-6 T 12-10-2018 VAPA_1c16180 8421879c0659baf88bee888cec465739 58 Pfam PF04964 Flp/Fap pilin component 5 36 1.5E-9 T 12-10-2018 IPR007047 Flp/Fap pilin component VAPA_1c21370 ef3ed7c73183f5463482f6e974e80b56 168 PIRSF PIRSF003174 8 168 6.7E-67 T 12-10-2018 IPR010292 Uncharacterised protein family CreA VAPA_1c21370 ef3ed7c73183f5463482f6e974e80b56 168 Pfam PF05981 CreA protein 35 160 3.3E-54 T 12-10-2018 IPR010292 Uncharacterised protein family CreA VAPA_1c02100 207b2c1ff4c6844b5a1893ed619f067a 130 Pfam PF04138 GtrA-like protein 10 127 3.7E-17 T 12-10-2018 IPR007267 GtrA-like protein GO:0000271|GO:0016021 VAPA_1c37270 449038b41f18d0800c169d6a4cad0bfe 121 Pfam PF03779 SPW repeat 11 55 7.4E-13 T 12-10-2018 IPR005530 SPW repeat VAPA_1c37270 449038b41f18d0800c169d6a4cad0bfe 121 Pfam PF03779 SPW repeat 61 107 9.6E-14 T 12-10-2018 IPR005530 SPW repeat VAPA_1c26180 b8fae723d5c5d89b05b4e4e17b8938e5 493 Pfam PF02696 Uncharacterized ACR, YdiU/UPF0061 family 15 461 1.2E-132 T 12-10-2018 IPR003846 Uncharacterised protein family UPF0061 VAPA_1c26180 b8fae723d5c5d89b05b4e4e17b8938e5 493 Hamap MF_00692 UPF0061 protein YdiU [ydiU]. 13 479 43.533 T 12-10-2018 IPR003846 Uncharacterised protein family UPF0061 VAPA_1c15690 40f8f83edb73a6ee258cab4de2522a31 239 Pfam PF00293 NUDIX domain 74 187 2.1E-15 T 12-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 VAPA_1c15690 40f8f83edb73a6ee258cab4de2522a31 239 Gene3D G3DSA:3.90.79.10 55 235 7.2E-48 T 12-10-2018 VAPA_1c15690 40f8f83edb73a6ee258cab4de2522a31 239 SUPERFAMILY SSF55811 62 230 1.9E-32 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 VAPA_1c33650 952a4ede717b3649f0dbaea0c41d646e 129 Pfam PF07007 Lysozyme inhibitor LprI 37 121 2.2E-21 T 12-10-2018 IPR009739 Lysozyme inhibitor LprI, N-terminal VAPA_1c33650 952a4ede717b3649f0dbaea0c41d646e 129 Gene3D G3DSA:1.20.1270.180 22 129 3.0E-21 T 12-10-2018 VAPA_1c21310 a2dbcb0eeb12405bb08256e30ae202b4 390 SUPERFAMILY SSF56059 137 246 4.08E-6 T 12-10-2018 VAPA_1c21310 a2dbcb0eeb12405bb08256e30ae202b4 390 Pfam PF11379 Protein of unknown function (DUF3182) 34 380 5.5E-142 T 12-10-2018 IPR021519 Protein of unknown function DUF3182 VAPA_2c11560 912766d58145a564b431735b5cbfe8fc 364 PIRSF PIRSF007313 1 363 5.6E-159 T 12-10-2018 IPR008773 Phosphonate metabolism protein PhnI GO:0019634 VAPA_2c11560 912766d58145a564b431735b5cbfe8fc 364 Pfam PF05861 Bacterial phosphonate metabolism protein (PhnI) 1 357 1.0E-160 T 12-10-2018 IPR008773 Phosphonate metabolism protein PhnI GO:0019634 VAPA_2c09160 8a7120e470fcc3fab4ea0d03af1b5d7d 333 Pfam PF01757 Acyltransferase family 7 311 2.9E-27 T 12-10-2018 IPR002656 Acyltransferase 3 GO:0016747 VAPA_2c06700 5687d56af14fb42579aa6132d0636eb8 426 Pfam PF11902 Protein of unknown function (DUF3422) 8 420 3.2E-136 T 12-10-2018 IPR021830 Protein of unknown function DUF3422 VAPA_1c33240 afb8db175507deb1d9da22c012fc4567 470 Pfam PF11067 Protein of unknown function (DUF2868) 161 446 3.7E-51 T 12-10-2018 IPR021296 Protein of unknown function DUF2868 VAPA_2c06170 b419e2333e4b68f26923928337dbab05 345 SUPERFAMILY SSF53187 48 283 2.67E-27 T 12-10-2018 VAPA_2c06170 b419e2333e4b68f26923928337dbab05 345 Gene3D G3DSA:3.40.630.10 25 231 1.0E-20 T 12-10-2018 VAPA_1c01940 fd58cca0bd7896516ada7a43fb14fc64 268 Pfam PF12974 ABC transporter, phosphonate, periplasmic substrate-binding protein 57 251 1.9E-16 T 12-10-2018 VAPA_1c01940 fd58cca0bd7896516ada7a43fb14fc64 268 Gene3D G3DSA:3.40.190.10 49 230 2.0E-10 T 12-10-2018 VAPA_1c01940 fd58cca0bd7896516ada7a43fb14fc64 268 Gene3D G3DSA:3.40.190.10 90 200 2.0E-10 T 12-10-2018 VAPA_1c45660 e4f76e6e529bf869561fe150ca376a98 158 Pfam PF10003 Integral membrane protein (DUF2244) 20 155 2.2E-41 T 12-10-2018 IPR019253 Protein of unknown function DUF2244, transmembrane VAPA_1c05510 27c479bbd7b20c895574da9cdbeafc52 209 SUPERFAMILY SSF81342 25 205 5.96E-34 T 12-10-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 VAPA_1c05510 27c479bbd7b20c895574da9cdbeafc52 209 Pfam PF01292 Prokaryotic cytochrome b561 26 202 4.2E-27 T 12-10-2018 IPR011577 Cytochrome b561, bacterial/Ni-hydrogenase GO:0009055|GO:0016021 VAPA_1c52690 9606af83ae265b0cede9d772fafbc576 167 Pfam PF05360 yiaA/B two helix domain 87 139 7.3E-15 T 12-10-2018 IPR008024 YiaAB two helix VAPA_1c52690 9606af83ae265b0cede9d772fafbc576 167 Pfam PF05360 yiaA/B two helix domain 18 70 2.6E-16 T 12-10-2018 IPR008024 YiaAB two helix VAPA_1c43220 3dd5daebb815b87fb73b87ae7f9914ae 115 Pfam PF03646 FlaG protein 20 112 5.5E-24 T 12-10-2018 IPR005186 FlaG protein VAPA_1c43220 3dd5daebb815b87fb73b87ae7f9914ae 115 Gene3D G3DSA:3.30.160.170 15 111 1.4E-16 T 12-10-2018 IPR035924 FlaG-like superfamily VAPA_1c43220 3dd5daebb815b87fb73b87ae7f9914ae 115 SUPERFAMILY SSF160214 18 114 5.36E-25 T 12-10-2018 IPR035924 FlaG-like superfamily VAPA_1c36730 d429463c463ac557c5eb3d12f24e64f6 445 SUPERFAMILY SSF56954 1 430 1.44E-80 T 12-10-2018 VAPA_1c36730 d429463c463ac557c5eb3d12f24e64f6 445 Gene3D G3DSA:1.20.1600.10 13 436 8.6E-71 T 12-10-2018 VAPA_1c36730 d429463c463ac557c5eb3d12f24e64f6 445 Pfam PF02321 Outer membrane efflux protein 257 430 3.8E-26 T 12-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 VAPA_1c36730 d429463c463ac557c5eb3d12f24e64f6 445 Pfam PF02321 Outer membrane efflux protein 53 226 5.0E-22 T 12-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 VAPA_1c53520 6226fe51a6361732f694a50294244b81 460 Pfam PF07804 HipA-like C-terminal domain 215 392 4.8E-24 T 12-10-2018 IPR012893 HipA-like, C-terminal VAPA_2c01380 50a3ea091c0e046dd4da6ce62d9bc86d 430 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 11 418 1.9E-108 T 12-10-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit VAPA_2c01380 50a3ea091c0e046dd4da6ce62d9bc86d 430 TIGRFAM TIGR00786 dctM: TRAP transporter, DctM subunit 18 424 1.2E-125 T 12-10-2018 IPR004681 TRAP transporter large membrane protein DctM GO:0016021 VAPA_2c01380 50a3ea091c0e046dd4da6ce62d9bc86d 430 PIRSF PIRSF006066 2 430 1.4E-150 T 12-10-2018 IPR004681 TRAP transporter large membrane protein DctM GO:0016021 VAPA_1c11000 75bd1db14b9eb2af803fe118153af517 407 Pfam PF02653 Branched-chain amino acid transport system / permease component 61 398 3.7E-46 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 VAPA_2c12890 20ed4faf6fc892bfd9ce5ddf75e5f6e2 94 Gene3D G3DSA:1.20.5.780 1 64 9.7E-6 T 12-10-2018 VAPA_2c12890 20ed4faf6fc892bfd9ce5ddf75e5f6e2 94 Pfam PF08681 Protein of unknown function (DUF1778) 5 61 5.4E-7 T 12-10-2018 IPR014795 Vibrio phage ICP1, Orf50 VAPA_2c12890 20ed4faf6fc892bfd9ce5ddf75e5f6e2 94 SUPERFAMILY SSF47598 1 43 2.32E-8 T 12-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 VAPA_2c12190 4664956587b9e854a88aefd7649f1e58 216 Gene3D G3DSA:3.40.50.1820 62 212 6.2E-11 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c20140 5cb54726d0e9f62c99dd8eb76f333763 203 Pfam PF13338 Transcriptional regulator, AbiEi antitoxin 13 55 7.3E-10 T 12-10-2018 IPR025159 Transcriptional regulator, AbiEi antitoxin VAPA_2c09720 bd0be901ace5bd1fd93c563a4c0d5993 341 Gene3D G3DSA:3.40.190.150 38 330 2.9E-82 T 12-10-2018 VAPA_2c09720 bd0be901ace5bd1fd93c563a4c0d5993 341 PIRSF PIRSF017082 5 340 8.9E-69 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_2c09720 bd0be901ace5bd1fd93c563a4c0d5993 341 Gene3D G3DSA:3.40.190.10 135 265 2.9E-82 T 12-10-2018 VAPA_2c09720 bd0be901ace5bd1fd93c563a4c0d5993 341 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 58 336 1.4E-54 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 VAPA_1c16990 d680e78a5fb85dcf7f8d40cc7dcf2a16 117 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 5 108 2.1E-26 T 12-10-2018 IPR039428 NADH-ubiquinone oxidoreductase chain 4L/Mnh complex subunit C1-like VAPA_1c26710 858249c89121e1f9cb37e981daeb67a9 120 Gene3D G3DSA:3.40.1440.10 21 118 6.6E-11 T 12-10-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 VAPA_1c10490 fcbdae24d59376fcb72078b647a8aabb 106 Pfam PF11142 Protein of unknown function (DUF2917) 33 94 2.0E-20 T 12-10-2018 IPR021317 Protein of unknown function DUF2917 VAPA_2c12820 af3434bd5a758d884e73df7d0d8f7a22 212 Gene3D G3DSA:3.40.50.300 2 172 2.0E-18 T 12-10-2018 VAPA_2c12820 af3434bd5a758d884e73df7d0d8f7a22 212 SUPERFAMILY SSF52540 2 159 9.42E-9 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c24970 b1b0d9e0e69496297a744b9ca78d5db4 175 Hamap MF_00209 Inorganic pyrophosphatase [ppa]. 14 174 36.555 T 12-10-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 VAPA_1c24970 b1b0d9e0e69496297a744b9ca78d5db4 175 ProSitePatterns PS00387 Inorganic pyrophosphatase signature. 66 72 - T 12-10-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 VAPA_1c24970 b1b0d9e0e69496297a744b9ca78d5db4 175 SUPERFAMILY SSF50324 3 175 1.57E-68 T 12-10-2018 IPR036649 Inorganic pyrophosphatase superfamily GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 VAPA_1c24970 b1b0d9e0e69496297a744b9ca78d5db4 175 Pfam PF00719 Inorganic pyrophosphatase 18 174 7.7E-52 T 12-10-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 VAPA_1c24970 b1b0d9e0e69496297a744b9ca78d5db4 175 Gene3D G3DSA:3.90.80.10 1 175 2.1E-68 T 12-10-2018 IPR036649 Inorganic pyrophosphatase superfamily GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 VAPA_2c10620 ddd6e003df0f0ede72ac3fb9791dee08 91 Pfam PF07235 Protein of unknown function (DUF1427) 2 81 4.3E-35 T 12-10-2018 IPR009872 Protein of unknown function DUF1427 VAPA_2c10620 ddd6e003df0f0ede72ac3fb9791dee08 91 TIGRFAM TIGR03510 XapX: XapX domain 3 49 6.0E-19 T 12-10-2018 IPR020017 XapX domain VAPA_1c25020 0949643a32b9b0fb6a4fce32f4613b85 135 Pfam PF01219 Prokaryotic diacylglycerol kinase 31 128 1.0E-31 T 12-10-2018 IPR000829 DAGK family GO:0008654|GO:0016020|GO:0016301 KEGG: 00561+2.7.1.107|KEGG: 00564+2.7.1.107|KEGG: 04070+2.7.1.107|MetaCyc: PWY-7039|MetaCyc: PWY-7817 VAPA_1c25020 0949643a32b9b0fb6a4fce32f4613b85 135 Gene3D G3DSA:1.10.3830.10 15 134 2.4E-36 T 12-10-2018 IPR036945 Diacylglycerol kinase (DAGK) superfamily GO:0008610|GO:0016020|GO:0016301 KEGG: 00561+2.7.1.107|KEGG: 00564+2.7.1.107|KEGG: 04070+2.7.1.107|MetaCyc: PWY-7039|MetaCyc: PWY-7817 VAPA_1c01640 e5f3d5faa3221ed3a5fee78c9dfd93f6 409 PIRSF PIRSF036542 1 409 2.5E-203 T 12-10-2018 IPR011415 Predicted bifunctional spore maturation protein, fused SpmA/SpmB VAPA_1c01640 e5f3d5faa3221ed3a5fee78c9dfd93f6 409 Pfam PF07670 Nucleoside recognition 52 157 2.0E-8 T 12-10-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 VAPA_2c12960 b84e4cca1b8dff82101916f9616d980b 226 SUPERFAMILY SSF161098 13 208 1.7E-33 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_2c12960 b84e4cca1b8dff82101916f9616d980b 226 Gene3D G3DSA:1.10.3720.10 1 224 9.4E-45 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_2c12960 b84e4cca1b8dff82101916f9616d980b 226 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 11 112 9.6E-19 T 12-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 VAPA_2c12960 b84e4cca1b8dff82101916f9616d980b 226 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 44 222 1.1E-14 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 VAPA_1c00150 fc9fcf50f4b8eaf1ee75b78df9e8916d 190 Pfam PF07813 LTXXQ motif family protein 72 163 4.0E-21 T 12-10-2018 IPR012899 LTXXQ motif family protein GO:0042597 VAPA_2c08020 dcca49efe084924b225d7a9cade16d64 249 Pfam PF01925 Sulfite exporter TauE/SafE 19 239 2.1E-18 T 12-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 VAPA_1c53170 9c3dd4078b956023a624ce9263cf49b7 104 Pfam PF03626 Prokaryotic Cytochrome C oxidase subunit IV 16 85 2.1E-13 T 12-10-2018 IPR005171 Cytochrome C oxidase subunit IV, prokaryotes GO:0016021 VAPA_1c14030 a11faa5942e2d8f71aa18ed15496dbb0 450 SUPERFAMILY SSF53474 29 366 1.77E-12 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c14030 a11faa5942e2d8f71aa18ed15496dbb0 450 Gene3D G3DSA:3.40.50.1820 48 213 1.0E-5 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_2c09670 a4ea908941629f766ee44b9bf33ec164 154 SUPERFAMILY SSF54427 2 153 1.68E-38 T 12-10-2018 IPR032710 NTF2-like domain superfamily VAPA_2c09670 a4ea908941629f766ee44b9bf33ec164 154 Gene3D G3DSA:3.10.450.50 3 154 2.2E-38 T 12-10-2018 VAPA_2c09670 a4ea908941629f766ee44b9bf33ec164 154 Pfam PF00866 Ring hydroxylating beta subunit 15 147 4.5E-12 T 12-10-2018 IPR000391 Ring-hydroxylating dioxygenase beta subunit GO:0006725|GO:0055114 VAPA_1c52770 035b9161540253eaee4fa568892ea1f2 335 Pfam PF00892 EamA-like transporter family 9 154 3.7E-8 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 VAPA_1c52770 035b9161540253eaee4fa568892ea1f2 335 Pfam PF00892 EamA-like transporter family 171 308 3.8E-11 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 VAPA_1c52770 035b9161540253eaee4fa568892ea1f2 335 SUPERFAMILY SSF103481 233 308 4.32E-5 T 12-10-2018 VAPA_1c52770 035b9161540253eaee4fa568892ea1f2 335 SUPERFAMILY SSF103481 48 159 2.35E-6 T 12-10-2018 VAPA_1c27460 bed12a450b52e86a4e8e8284d431bc96 202 SUPERFAMILY SSF51197 24 198 5.08E-29 T 12-10-2018 VAPA_1c27460 bed12a450b52e86a4e8e8284d431bc96 202 Pfam PF13532 2OG-Fe(II) oxygenase superfamily 69 189 5.2E-9 T 12-10-2018 IPR027450 Alpha-ketoglutarate-dependent dioxygenase AlkB-like VAPA_1c27460 bed12a450b52e86a4e8e8284d431bc96 202 Gene3D G3DSA:2.60.120.590 15 202 4.9E-32 T 12-10-2018 IPR037151 Alpha-ketoglutarate-dependent dioxygenase AlkB-like superfamily VAPA_1c26690 e46391ba3704e4fb390b51bf85a6f69c 190 Pfam PF09998 Uncharacterized protein conserved in bacteria (DUF2239) 11 182 2.3E-66 T 12-10-2018 IPR018715 Protein of unknown function DUF2239 VAPA_2c13310 1a97149090960c5ae41506eeaa6ab423 110 Pfam PF04956 TrbC/VIRB2 family 19 104 4.6E-15 T 12-10-2018 IPR007039 Conjugal transfer TrbC/type IV secretion VirB2 VAPA_1c16690 0b4d3a2c65e37682002969795a2d1205 199 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 30 161 2.1E-23 T 12-10-2018 IPR007387 TRAP transporter, small membrane protein DctQ VAPA_2c07500 a691b995b1397b4ac94099f72a70534c 245 Pfam PF17194 Transcriptional regulator, AbiEi antitoxin N-terminal domain 6 95 7.8E-28 T 12-10-2018 IPR033455 Transcriptional regulator AbiEi antitoxin, N-terminal domain VAPA_2c07500 a691b995b1397b4ac94099f72a70534c 245 Pfam PF11459 Transcriptional regulator, AbiEi antitoxin, Type IV TA system 98 240 3.4E-37 T 12-10-2018 IPR021561 Transcriptional regulator, AbiEi 3 antitoxin, Type IV TA system VAPA_1c46860 fd016fae082fcd6b33de6a45330a1d4c 837 Pfam PF14022 Protein of unknown function (DUF4238) 16 295 1.4E-8 T 12-10-2018 IPR025332 Protein of unknown function DUF4238 VAPA_1c34240 8f3b2a072d0ab259c5e23420214c58c8 405 SUPERFAMILY SSF103473 18 400 3.92E-53 T 12-10-2018 IPR036259 MFS transporter superfamily VAPA_1c34240 8f3b2a072d0ab259c5e23420214c58c8 405 Gene3D G3DSA:1.20.1720.10 17 396 1.6E-73 T 12-10-2018 VAPA_1c34240 8f3b2a072d0ab259c5e23420214c58c8 405 Pfam PF07690 Major Facilitator Superfamily 26 340 1.6E-32 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 VAPA_1c29920 31e8a96d9b72528489241ff07d8a6d89 293 SUPERFAMILY SSF53474 23 256 3.64E-47 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c29920 31e8a96d9b72528489241ff07d8a6d89 293 Gene3D G3DSA:3.40.50.1820 5 256 3.3E-56 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c29920 31e8a96d9b72528489241ff07d8a6d89 293 Pfam PF07859 alpha/beta hydrolase fold 52 250 8.4E-49 T 12-10-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0016787 VAPA_1c48740 3cc697b05b71d940528bb58c0674992f 223 Pfam PF13548 Domain of unknown function (DUF4126) 10 182 1.5E-53 T 12-10-2018 IPR025196 Domain of unknown function DUF4126 VAPA_1c40620 767a7d0c55b8674bcb30fd7559b11839 289 Gene3D G3DSA:3.20.20.60 2 289 1.5E-93 T 12-10-2018 VAPA_1c40620 767a7d0c55b8674bcb30fd7559b11839 289 Pfam PF13714 Phosphoenolpyruvate phosphomutase 9 251 2.3E-51 T 12-10-2018 VAPA_1c40620 767a7d0c55b8674bcb30fd7559b11839 289 SUPERFAMILY SSF51621 6 283 1.17E-81 T 12-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 VAPA_1c39850 9ee411270a6a7dede105bfe0feb9d543 340 SUPERFAMILY SSF161098 136 316 1.44E-23 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c39850 9ee411270a6a7dede105bfe0feb9d543 340 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 161 326 4.1E-15 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 VAPA_1c39850 9ee411270a6a7dede105bfe0feb9d543 340 Gene3D G3DSA:1.10.3720.10 135 330 8.0E-20 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c34300 05c5f2d6080da96bc015ac58d1498ee8 186 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 23 152 1.9E-27 T 12-10-2018 IPR007387 TRAP transporter, small membrane protein DctQ VAPA_1c44550 daa4dcca9393e547d7a3b8c7202183ee 906 TIGRFAM TIGR01760 tape_meas_TP901: phage tail tape measure protein, TP901 family, core region 40 344 2.3E-48 T 12-10-2018 IPR010090 Phage tail tape measure protein VAPA_1c44550 daa4dcca9393e547d7a3b8c7202183ee 906 Pfam PF10145 Phage-related minor tail protein 76 286 1.6E-27 T 12-10-2018 IPR010090 Phage tail tape measure protein VAPA_2c12640 44f07270b9bd97810a3dc97f7136217c 113 Pfam PF11604 Copper binding periplasmic protein CusF 58 101 1.1E-4 T 12-10-2018 IPR021647 Copper binding periplasmic protein CusF VAPA_2c02770 ee52a49ab2e87475ff7a916667efdd90 210 Pfam PF14235 Domain of unknown function (DUF4337) 47 206 1.8E-38 T 12-10-2018 IPR025570 Protein of unknown function DUF4337 VAPA_1c53040 889830aebb3d73a55517f7d3196c5e59 157 PRINTS PR01576 Peptide deformylase signature 74 85 2.6E-35 T 12-10-2018 IPR023635 Peptide deformylase VAPA_1c53040 889830aebb3d73a55517f7d3196c5e59 157 PRINTS PR01576 Peptide deformylase signature 17 46 2.6E-35 T 12-10-2018 IPR023635 Peptide deformylase VAPA_1c53040 889830aebb3d73a55517f7d3196c5e59 157 PRINTS PR01576 Peptide deformylase signature 105 134 2.6E-35 T 12-10-2018 IPR023635 Peptide deformylase VAPA_1c53040 889830aebb3d73a55517f7d3196c5e59 157 PRINTS PR01576 Peptide deformylase signature 86 104 2.6E-35 T 12-10-2018 IPR023635 Peptide deformylase VAPA_1c53040 889830aebb3d73a55517f7d3196c5e59 157 Pfam PF01327 Polypeptide deformylase 2 137 6.6E-46 T 12-10-2018 IPR023635 Peptide deformylase VAPA_1c53040 889830aebb3d73a55517f7d3196c5e59 157 TIGRFAM TIGR00079 pept_deformyl: peptide deformylase 1 144 1.3E-51 T 12-10-2018 IPR023635 Peptide deformylase VAPA_1c53040 889830aebb3d73a55517f7d3196c5e59 157 PIRSF PIRSF004749 1 156 4.5E-50 T 12-10-2018 IPR023635 Peptide deformylase VAPA_1c53040 889830aebb3d73a55517f7d3196c5e59 157 SUPERFAMILY SSF56420 1 149 3.79E-54 T 12-10-2018 IPR036821 Peptide deformylase superfamily VAPA_1c53040 889830aebb3d73a55517f7d3196c5e59 157 Hamap MF_00163 Peptide deformylase [def]. 1 147 24.843 T 12-10-2018 IPR023635 Peptide deformylase VAPA_1c53040 889830aebb3d73a55517f7d3196c5e59 157 Gene3D G3DSA:3.90.45.10 1 152 5.2E-55 T 12-10-2018 IPR036821 Peptide deformylase superfamily VAPA_1c09710 ac2c307ad2ed256ebbe6322894425c12 432 Hamap MF_00913 Probable peptidoglycan glycosyltransferase FtsW [ftsW]. 56 431 39.931 T 12-10-2018 IPR013437 Probable peptidoglycan glycosyltransferase FtsW GO:0009252|GO:0016021|GO:0051301 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 VAPA_1c09710 ac2c307ad2ed256ebbe6322894425c12 432 TIGRFAM TIGR02614 ftsW: cell division protein FtsW 58 422 7.5E-116 T 12-10-2018 IPR013437 Probable peptidoglycan glycosyltransferase FtsW GO:0009252|GO:0016021|GO:0051301 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 VAPA_1c09710 ac2c307ad2ed256ebbe6322894425c12 432 Pfam PF01098 Cell cycle protein 60 424 2.3E-100 T 12-10-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 VAPA_1c39890 810396df6589211206925c97b8fc1ef1 329 Gene3D G3DSA:3.40.190.10 40 312 1.6E-67 T 12-10-2018 VAPA_1c39890 810396df6589211206925c97b8fc1ef1 329 Gene3D G3DSA:3.40.190.10 112 211 1.6E-67 T 12-10-2018 VAPA_1c39890 810396df6589211206925c97b8fc1ef1 329 SMART SM00062 37 247 0.0098 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF VAPA_1c39890 810396df6589211206925c97b8fc1ef1 329 Pfam PF09084 NMT1/THI5 like 75 196 1.8E-13 T 12-10-2018 IPR015168 SsuA/THI5-like VAPA_1c39890 810396df6589211206925c97b8fc1ef1 329 SUPERFAMILY SSF53850 40 259 2.13E-36 T 12-10-2018 VAPA_1c46380 1aa06be252881dd2425cf96c6b464abb 143 Pfam PF08897 Domain of unknown function (DUF1841) 5 139 5.0E-56 T 12-10-2018 IPR014993 Protein of unknown function DUF1841 VAPA_1c42420 589c2528bb2a60a1fab1017e0b564416 128 Pfam PF13586 Transposase DDE domain 42 121 4.5E-10 T 12-10-2018 IPR025668 Transposase DDE domain VAPA_2c04720 63b57ad5a7e623b3051b85cf31c1791a 149 Pfam PF10116 Protein required for attachment to host cells 5 140 1.7E-32 T 12-10-2018 IPR019291 Host attachment protein VAPA_1c18610 90c39a03c5674e4e75a7337fb611bc99 455 Pfam PF02646 RmuC family 150 439 2.5E-77 T 12-10-2018 IPR003798 DNA recombination RmuC VAPA_1c18610 90c39a03c5674e4e75a7337fb611bc99 455 SUPERFAMILY SSF58113 53 188 1.96E-5 T 12-10-2018 VAPA_1c42180 77a6ecf99b55800432c3f088128d9f97 202 Pfam PF11748 Protein of unknown function (DUF3306) 4 108 2.3E-29 T 12-10-2018 IPR021735 Protein of unknown function DUF3306 VAPA_1c13160 3f6fecccde6178d34aca04f41def1913 162 Pfam PF07331 Tripartite tricarboxylate transporter TctB family 10 152 3.7E-22 T 12-10-2018 IPR009936 Protein of unknown function DUF1468 VAPA_1c09880 6693c41102b43ae1a234c6e1a5b04f80 283 Gene3D G3DSA:3.30.1150.10 115 274 1.8E-13 T 12-10-2018 VAPA_1c09880 6693c41102b43ae1a234c6e1a5b04f80 283 SUPERFAMILY SSF74653 161 275 4.32E-16 T 12-10-2018 VAPA_1c09880 6693c41102b43ae1a234c6e1a5b04f80 283 Pfam PF13103 TonB C terminal 182 254 4.3E-6 T 12-10-2018 VAPA_1c09880 6693c41102b43ae1a234c6e1a5b04f80 283 TIGRFAM TIGR01352 tonB_Cterm: TonB family C-terminal domain 199 250 3.0E-7 T 12-10-2018 IPR006260 TonB/TolA, C-terminal VAPA_1c48630 9eeabbac9d82c1ada2f05d19fc823043 162 Pfam PF04073 Aminoacyl-tRNA editing domain 35 153 4.0E-26 T 12-10-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 VAPA_1c48630 9eeabbac9d82c1ada2f05d19fc823043 162 SUPERFAMILY SSF55826 15 161 1.44E-34 T 12-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 VAPA_1c48630 9eeabbac9d82c1ada2f05d19fc823043 162 Gene3D G3DSA:3.90.960.10 8 162 8.3E-43 T 12-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 VAPA_1c02410 d2e60d79e7ae5e7a870f47f2dc3fa27b 126 Pfam PF13665 Domain of unknown function (DUF4150) 9 111 4.2E-36 T 12-10-2018 IPR025425 Domain of unknown function DUF4150 VAPA_1c42930 162018e65d2395f77308ff9b86367be4 248 Gene3D G3DSA:3.20.20.190 11 239 6.7E-71 T 12-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 VAPA_1c42930 162018e65d2395f77308ff9b86367be4 248 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 15 242 5.5E-34 T 12-10-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 VAPA_1c42930 162018e65d2395f77308ff9b86367be4 248 SUPERFAMILY SSF51695 8 245 2.22E-60 T 12-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 VAPA_1c14310 37506ff16d3b539462427352d267e9f7 208 Pfam PF01810 LysE type translocator 15 199 3.2E-28 T 12-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 VAPA_1c14310 37506ff16d3b539462427352d267e9f7 208 PIRSF PIRSF006324 1 206 6.8E-55 T 12-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 VAPA_1c47530 0ca53bfcfd6a68d92ada8dece379b324 248 SUPERFAMILY SSF69593 50 245 6.15E-33 T 12-10-2018 VAPA_1c47530 0ca53bfcfd6a68d92ada8dece379b324 248 SMART SM00563 68 180 4.9E-30 T 12-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 VAPA_1c47530 0ca53bfcfd6a68d92ada8dece379b324 248 Pfam PF01553 Acyltransferase 63 176 3.3E-20 T 12-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 VAPA_1c25670 9c4c70f6d192fc957beb7006e825ed7e 162 Pfam PF14317 YcxB-like protein 95 140 4.0E-7 T 12-10-2018 IPR025588 YcxB-like protein VAPA_1c26230 ecd755a1d1535df0d50c140aa2e9de27 412 Pfam PF13458 Periplasmic binding protein 27 371 2.4E-66 T 12-10-2018 IPR028081 Leucine-binding protein domain VAPA_1c26230 ecd755a1d1535df0d50c140aa2e9de27 412 SUPERFAMILY SSF53822 26 371 1.24E-66 T 12-10-2018 IPR028082 Periplasmic binding protein-like I VAPA_1c26230 ecd755a1d1535df0d50c140aa2e9de27 412 Gene3D G3DSA:3.40.50.2300 27 362 9.4E-136 T 12-10-2018 VAPA_1c26230 ecd755a1d1535df0d50c140aa2e9de27 412 Gene3D G3DSA:3.40.50.2300 153 404 9.4E-136 T 12-10-2018 VAPA_2c00620 2cd2e6d943b3b73e1f969169fb1db676 297 Pfam PF02653 Branched-chain amino acid transport system / permease component 6 282 1.1E-34 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 VAPA_1c47820 30adf7eaf2f43ff1e0af482f8c6eb743 327 Pfam PF02653 Branched-chain amino acid transport system / permease component 49 312 5.3E-46 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 VAPA_1c10910 237ce51bd0403b8653216f22d1f8cc3c 548 SUPERFAMILY SSF48208 224 429 6.72E-15 T 12-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 VAPA_1c32970 294a37bb96b1bea071d429767a01d5e9 411 Gene3D G3DSA:3.40.50.2000 212 389 8.0E-33 T 12-10-2018 VAPA_1c32970 294a37bb96b1bea071d429767a01d5e9 411 Pfam PF13692 Glycosyl transferases group 1 233 372 1.6E-19 T 12-10-2018 VAPA_1c32970 294a37bb96b1bea071d429767a01d5e9 411 SUPERFAMILY SSF53756 2 403 1.91E-56 T 12-10-2018 VAPA_1c32970 294a37bb96b1bea071d429767a01d5e9 411 Gene3D G3DSA:3.40.50.2000 1 211 1.7E-16 T 12-10-2018 VAPA_1c32970 294a37bb96b1bea071d429767a01d5e9 411 Pfam PF13579 Glycosyl transferase 4-like domain 16 202 2.0E-26 T 12-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 VAPA_1c48440 71d572f5fbe96535707ac03aa881d11e 278 Gene3D G3DSA:3.90.1070.10 108 189 4.1E-19 T 12-10-2018 VAPA_1c48440 71d572f5fbe96535707ac03aa881d11e 278 Pfam PF08282 haloacid dehalogenase-like hydrolase 31 109 2.1E-8 T 12-10-2018 VAPA_1c48440 71d572f5fbe96535707ac03aa881d11e 278 Gene3D G3DSA:3.40.50.1000 31 267 4.1E-19 T 12-10-2018 IPR023214 HAD superfamily VAPA_1c48440 71d572f5fbe96535707ac03aa881d11e 278 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 31 236 2.1E-16 T 12-10-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 VAPA_1c48440 71d572f5fbe96535707ac03aa881d11e 278 SUPERFAMILY SSF56784 31 271 2.13E-23 T 12-10-2018 IPR036412 HAD-like superfamily VAPA_1c33260 f2b232fd97ca4b4934bc5797200906a2 119 SUPERFAMILY SSF54909 32 80 6.57E-6 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel VAPA_1c27360 a64cf28245a4c2bfbdce3702bfc36f72 45 Pfam PF03597 Cytochrome oxidase maturation protein cbb3-type 2 45 2.1E-17 T 12-10-2018 IPR004714 Cytochrome oxidase maturation protein cbb3-type VAPA_1c27360 a64cf28245a4c2bfbdce3702bfc36f72 45 TIGRFAM TIGR00847 ccoS: cytochrome oxidase maturation protein, cbb3-type 1 42 1.5E-11 T 12-10-2018 IPR004714 Cytochrome oxidase maturation protein cbb3-type VAPA_1c02630 4a626e5591e3eb21470df3765769cf54 383 Pfam PF09937 Uncharacterized protein conserved in bacteria (DUF2169) 23 324 6.3E-84 T 12-10-2018 IPR018683 Domain of unknown function DUF2169 VAPA_1c18050 3eb1ee0d70002e261591dfb098e38d6c 283 TIGRFAM TIGR00163 PS_decarb: phosphatidylserine decarboxylase 52 279 1.6E-71 T 12-10-2018 IPR033177 Phosphatidylserine decarboxylase GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669|Reactome: R-HSA-1483213 VAPA_1c18050 3eb1ee0d70002e261591dfb098e38d6c 283 Hamap MF_00662 Phosphatidylserine decarboxylase proenzyme [psd]. 10 281 45.114 T 12-10-2018 IPR033178 Phosphatidylserine decarboxylase, prokaryotic type 1 GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669 VAPA_1c18050 3eb1ee0d70002e261591dfb098e38d6c 283 Pfam PF02666 Phosphatidylserine decarboxylase 63 278 5.8E-58 T 12-10-2018 IPR003817 Phosphatidylserine decarboxylase-related GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669|Reactome: R-HSA-1483213 VAPA_1c34530 e43924c235e3f5f13a966d6a95e3c649 140 Pfam PF07883 Cupin domain 51 103 3.1E-8 T 12-10-2018 IPR013096 Cupin 2, conserved barrel VAPA_1c34530 e43924c235e3f5f13a966d6a95e3c649 140 SUPERFAMILY SSF51182 29 136 4.11E-17 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily VAPA_1c34530 e43924c235e3f5f13a966d6a95e3c649 140 Gene3D G3DSA:2.60.120.10 5 131 1.5E-36 T 12-10-2018 IPR014710 RmlC-like jelly roll fold VAPA_1c44760 08331ca563277fa0b7837a5bff370499 216 Gene3D G3DSA:1.10.260.40 11 65 1.5E-8 T 12-10-2018 VAPA_1c44760 08331ca563277fa0b7837a5bff370499 216 Gene3D G3DSA:2.10.109.10 84 214 9.4E-13 T 12-10-2018 VAPA_1c44760 08331ca563277fa0b7837a5bff370499 216 SUPERFAMILY SSF51306 121 209 3.79E-15 T 12-10-2018 IPR036286 LexA/Signal peptidase-like superfamily VAPA_1c44760 08331ca563277fa0b7837a5bff370499 216 Pfam PF00717 Peptidase S24-like 128 186 1.5E-9 T 12-10-2018 IPR015927 Peptidase S24/S26A/S26B/S26C VAPA_1c14330 009e17741d77e535fb15dfa58a4ae2ca 164 Pfam PF00583 Acetyltransferase (GNAT) family 37 138 7.8E-16 T 12-10-2018 IPR000182 GNAT domain VAPA_1c14330 009e17741d77e535fb15dfa58a4ae2ca 164 SUPERFAMILY SSF55729 11 163 2.23E-33 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase VAPA_1c14330 009e17741d77e535fb15dfa58a4ae2ca 164 Gene3D G3DSA:3.40.630.30 4 163 8.7E-41 T 12-10-2018 VAPA_1c16200 27dd3d99c19685060627927e68d283d5 154 Pfam PF07811 TadE-like protein 12 54 2.7E-11 T 12-10-2018 IPR012495 TadE-like VAPA_1c47160 04dbb16d071b104a68a63e32f9de268c 346 Pfam PF06250 Protein of unknown function (DUF1016) 12 278 2.8E-78 T 12-10-2018 IPR009362 Protein of unknown function DUF1016 VAPA_1c04650 080c137e15a0e590e627340e756e3b8a 159 SUPERFAMILY SSF55811 8 153 5.28E-22 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 VAPA_1c04650 080c137e15a0e590e627340e756e3b8a 159 Pfam PF00293 NUDIX domain 8 126 8.1E-13 T 12-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 VAPA_1c04650 080c137e15a0e590e627340e756e3b8a 159 Gene3D G3DSA:3.90.79.10 3 158 6.4E-34 T 12-10-2018 VAPA_1c07690 edb4a066eb1b9fb8984586118035ac80 363 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 60 287 1.5E-13 T 12-10-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0030288|GO:0055085 VAPA_1c07690 edb4a066eb1b9fb8984586118035ac80 363 Gene3D G3DSA:3.40.190.170 45 350 4.7E-51 T 12-10-2018 IPR038404 TRAP transporter solute receptor DctP superfamily VAPA_1c38900 688c6915f060084ab68e0c796626669f 161 Pfam PF02674 Colicin V production protein 4 144 1.0E-31 T 12-10-2018 IPR003825 Colicin V production, CvpA GO:0009403|GO:0016020 VAPA_1c02080 65f9cb97b9a4a12ac6e72fb38c97fe67 593 Pfam PF02366 Dolichyl-phosphate-mannose-protein mannosyltransferase 169 279 2.0E-6 T 12-10-2018 IPR003342 Glycosyl transferase family 39/83 GO:0000030|GO:0006493|GO:0016020 Reactome: R-HSA-5173105 VAPA_1c24010 e646672b820a931b4b5f085e07c48d0d 157 Pfam PF07331 Tripartite tricarboxylate transporter TctB family 7 148 5.7E-19 T 12-10-2018 IPR009936 Protein of unknown function DUF1468 VAPA_1c03570 b50a826060680ef95e8f0afd3732e0a8 223 Pfam PF13358 DDE superfamily endonuclease 32 180 3.4E-27 T 12-10-2018 IPR038717 Tc1-like transposase, DDE domain VAPA_1c04160 54559d0a0776ad06004fb5e09e7c8c50 167 TIGRFAM TIGR01837 PHA_granule_1: poly(hydroxyalkanoate) granule-associated protein 15 130 1.4E-30 T 12-10-2018 IPR008769 Poly granule associated VAPA_1c04160 54559d0a0776ad06004fb5e09e7c8c50 167 Pfam PF05597 Poly(hydroxyalcanoate) granule associated protein (phasin) 11 130 1.8E-41 T 12-10-2018 IPR008769 Poly granule associated VAPA_1c28350 7d196dc2542a90f9ed6295c602c5977e 52 Pfam PF11752 Protein of unknown function (DUF3309) 5 52 2.7E-22 T 12-10-2018 IPR021738 Protein of unknown function DUF3309 VAPA_1c03720 a4e55a0ae73a6865386c794c6b6e59de 283 Gene3D G3DSA:1.10.3720.10 10 280 3.8E-58 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c03720 a4e55a0ae73a6865386c794c6b6e59de 283 SUPERFAMILY SSF161098 3 276 1.21E-56 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c03720 a4e55a0ae73a6865386c794c6b6e59de 283 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 95 273 2.3E-12 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 VAPA_1c02220 b24ad419580b54a83805b17aaa3aab2d 240 SUPERFAMILY SSF52499 33 237 1.7E-49 T 12-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 VAPA_1c02220 b24ad419580b54a83805b17aaa3aab2d 240 Pfam PF00857 Isochorismatase family 37 235 4.8E-34 T 12-10-2018 IPR000868 Isochorismatase-like GO:0003824 VAPA_1c02220 b24ad419580b54a83805b17aaa3aab2d 240 Gene3D G3DSA:3.40.50.850 33 239 4.9E-78 T 12-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 VAPA_1c37630 e81129c35811e3227d0d333e34e410a1 367 Pfam PF10994 Protein of unknown function (DUF2817) 12 351 4.4E-128 T 12-10-2018 IPR021259 Protein of unknown function DUF2817 VAPA_1c37630 e81129c35811e3227d0d333e34e410a1 367 SUPERFAMILY SSF53187 48 284 3.97E-20 T 12-10-2018 VAPA_1c06740 3cded1cc5a88bcb23ba39d22be18fe18 271 Pfam PF06629 MltA-interacting protein MipA 54 271 5.8E-37 T 12-10-2018 IPR010583 MltA-interacting MipA VAPA_1c20020 0022ad4e67ae82fcafbebe5786219f5f 428 Pfam PF12704 MacB-like periplasmic core domain 19 246 1.1E-16 T 12-10-2018 IPR025857 MacB-like periplasmic core domain VAPA_1c20020 0022ad4e67ae82fcafbebe5786219f5f 428 Pfam PF02687 FtsX-like permease family 322 421 1.3E-13 T 12-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 VAPA_1c22150 a30cb77cf44e3cc1b8b6a34f134c1e03 99 Gene3D G3DSA:3.40.190.10 43 99 7.0E-10 T 12-10-2018 VAPA_2c08830 55358a644f4792b67407019769bfbde3 233 Pfam PF01738 Dienelactone hydrolase family 14 227 2.4E-54 T 12-10-2018 IPR002925 Dienelactone hydrolase GO:0016787 VAPA_2c08830 55358a644f4792b67407019769bfbde3 233 Gene3D G3DSA:3.40.50.1820 6 228 3.9E-59 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_2c08830 55358a644f4792b67407019769bfbde3 233 SUPERFAMILY SSF53474 4 230 4.45E-47 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c19890 b917b62d19f2f2490c1bb40040c1b5d1 155 Gene3D G3DSA:3.10.180.10 1 120 7.4E-46 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase VAPA_1c19890 b917b62d19f2f2490c1bb40040c1b5d1 155 SUPERFAMILY SSF54593 2 118 8.19E-18 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase VAPA_1c17870 7d03fa27b4174df280fdcaf5e18cc644 129 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 2 127 6.0E-15 T 12-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain VAPA_1c17870 7d03fa27b4174df280fdcaf5e18cc644 129 Gene3D G3DSA:3.10.180.10 1 128 2.8E-35 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase VAPA_1c17870 7d03fa27b4174df280fdcaf5e18cc644 129 SUPERFAMILY SSF54593 1 128 1.33E-30 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase VAPA_1c14570 5fd09b3ed763fc39e3a7f7c20a53e1ce 387 Pfam PF07786 Protein of unknown function (DUF1624) 12 221 4.8E-15 T 12-10-2018 IPR012429 Domain of unknown function DUF1624 Reactome: R-HSA-2024096|Reactome: R-HSA-2206291|Reactome: R-HSA-6798695 VAPA_1c08050 cbfd8d14201270bd08e9590d5ad7c03a 223 PIRSF PIRSF006324 1 208 9.0E-52 T 12-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 VAPA_1c08050 cbfd8d14201270bd08e9590d5ad7c03a 223 Pfam PF01810 LysE type translocator 16 205 5.7E-35 T 12-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 VAPA_1c02460 93b8ab14d787dfa5950b719dc1f41cfe 458 TIGRFAM TIGR03353 VI_chp_4: type VI secretion protein, VC_A0114 family 20 457 6.4E-139 T 12-10-2018 IPR010263 Type VI secretion protein, VC_A0114 VAPA_1c02460 93b8ab14d787dfa5950b719dc1f41cfe 458 Pfam PF05936 Bacterial Type VI secretion, VC_A0110, EvfL, ImpJ, VasE 34 456 1.4E-149 T 12-10-2018 IPR010263 Type VI secretion protein, VC_A0114 VAPA_1c22500 562585809dfbc8cd67f9fb2881dec828 269 SUPERFAMILY SSF51621 2 258 2.67E-80 T 12-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 VAPA_1c22500 562585809dfbc8cd67f9fb2881dec828 269 Gene3D G3DSA:3.20.20.60 2 266 8.2E-88 T 12-10-2018 VAPA_1c22500 562585809dfbc8cd67f9fb2881dec828 269 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 18 247 8.4E-63 T 12-10-2018 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 VAPA_1c30650 1a77f50d3679e20e6ea38ad070b68d23 395 Gene3D G3DSA:3.40.50.2300 37 360 1.3E-119 T 12-10-2018 VAPA_1c30650 1a77f50d3679e20e6ea38ad070b68d23 395 SUPERFAMILY SSF53822 27 392 4.37E-67 T 12-10-2018 IPR028082 Periplasmic binding protein-like I VAPA_1c30650 1a77f50d3679e20e6ea38ad070b68d23 395 Pfam PF13458 Periplasmic binding protein 27 366 4.6E-49 T 12-10-2018 IPR028081 Leucine-binding protein domain VAPA_1c30650 1a77f50d3679e20e6ea38ad070b68d23 395 Gene3D G3DSA:3.40.50.2300 149 369 1.3E-119 T 12-10-2018 VAPA_1c30870 7144608a2dd6b9425e26236cd3eb3421 74 Pfam PF11390 NADH-dependant formate dehydrogenase delta subunit FdsD 5 66 4.7E-26 T 12-10-2018 IPR021074 Formate dehydrogenase, delta subunit VAPA_1c00110 4b8b3615fd1504cbe3452313831ead9f 323 Pfam PF03706 Lysylphosphatidylglycerol synthase TM region 26 298 1.2E-16 T 12-10-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD VAPA_1c46270 c6b30450900c0e5e65c7f1aacaa0753e 155 Pfam PF07811 TadE-like protein 14 56 4.6E-8 T 12-10-2018 IPR012495 TadE-like VAPA_1c41010 d12e140a1023b58d584d5746d11371dd 332 Gene3D G3DSA:3.40.190.170 32 324 1.2E-65 T 12-10-2018 IPR038404 TRAP transporter solute receptor DctP superfamily VAPA_1c41010 d12e140a1023b58d584d5746d11371dd 332 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 39 298 3.3E-52 T 12-10-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0030288|GO:0055085 VAPA_1c13210 751b8f17d84999c6b69ae9cf02700e27 316 SUPERFAMILY SSF103481 58 160 2.35E-14 T 12-10-2018 VAPA_1c13210 751b8f17d84999c6b69ae9cf02700e27 316 SUPERFAMILY SSF103481 218 313 7.32E-11 T 12-10-2018 VAPA_1c13210 751b8f17d84999c6b69ae9cf02700e27 316 Pfam PF00892 EamA-like transporter family 176 311 1.6E-13 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 VAPA_1c13210 751b8f17d84999c6b69ae9cf02700e27 316 Pfam PF00892 EamA-like transporter family 23 158 9.1E-19 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 VAPA_1c03010 2475ccbec1359a342b075de2699a4b41 131 Pfam PF15586 Immunity protein 8 3 127 6.3E-24 T 12-10-2018 IPR028964 Immunity protein 8 VAPA_1c34160 53e549e89619c68df8f0afbc8ce4c520 248 Pfam PF03942 DTW domain 28 219 6.7E-41 T 12-10-2018 IPR005636 DTW VAPA_1c34160 53e549e89619c68df8f0afbc8ce4c520 248 SMART SM01144 27 225 6.4E-70 T 12-10-2018 IPR005636 DTW VAPA_2c13240 f92d9f558b1a673ee7b9a1c7ee4e4d15 445 Gene3D G3DSA:2.40.128.260 247 375 1.1E-39 T 12-10-2018 VAPA_2c13240 f92d9f558b1a673ee7b9a1c7ee4e4d15 445 Gene3D G3DSA:2.40.128.260 377 441 3.5E-7 T 12-10-2018 VAPA_2c13240 f92d9f558b1a673ee7b9a1c7ee4e4d15 445 Pfam PF03743 Bacterial conjugation TrbI-like protein 253 432 6.9E-46 T 12-10-2018 IPR005498 Type IV secretion system, VirB10 / TraB / TrbI VAPA_1c14770 eecc2e11f0d7b7a4b9b6550c629cedf4 254 Gene3D G3DSA:3.30.950.10 139 254 9.9E-38 T 12-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 VAPA_1c14770 eecc2e11f0d7b7a4b9b6550c629cedf4 254 SUPERFAMILY SSF53790 3 238 1.27E-56 T 12-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 VAPA_1c14770 eecc2e11f0d7b7a4b9b6550c629cedf4 254 Gene3D G3DSA:3.40.1010.10 3 138 8.4E-31 T 12-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 VAPA_1c16440 277e6da09e7ebe72b9e6027bc6507c62 305 Pfam PF02535 ZIP Zinc transporter 4 109 1.6E-11 T 12-10-2018 IPR003689 Zinc/iron permease GO:0016020|GO:0030001|GO:0046873|GO:0055085 VAPA_1c16440 277e6da09e7ebe72b9e6027bc6507c62 305 Pfam PF02535 ZIP Zinc transporter 114 277 1.5E-21 T 12-10-2018 IPR003689 Zinc/iron permease GO:0016020|GO:0030001|GO:0046873|GO:0055085 VAPA_1c54180 89ef5fc921dc484a67e1de3c6ebe8175 415 SUPERFAMILY SSF103473 8 401 5.36E-58 T 12-10-2018 IPR036259 MFS transporter superfamily VAPA_1c54180 89ef5fc921dc484a67e1de3c6ebe8175 415 Gene3D G3DSA:1.20.1250.20 20 401 3.1E-46 T 12-10-2018 VAPA_1c54180 89ef5fc921dc484a67e1de3c6ebe8175 415 Pfam PF07690 Major Facilitator Superfamily 24 343 4.8E-35 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 VAPA_1c06170 61100fc065d062b1d68bae92d0ea589d 382 Pfam PF15635 GHH signature containing HNH/Endo VII superfamily nuclease toxin 2 239 342 1.1E-24 T 12-10-2018 IPR028917 Tox-GHH2 domain VAPA_1c06170 61100fc065d062b1d68bae92d0ea589d 382 Pfam PF13665 Domain of unknown function (DUF4150) 21 134 1.9E-35 T 12-10-2018 IPR025425 Domain of unknown function DUF4150 VAPA_2c06200 297893957405a5608895bf68b3650e09 3229 Pfam PF16013 Domain of unknown function (DUF4781) 1217 1390 9.5E-22 T 12-10-2018 IPR031962 Domain of unknown function DUF4781 VAPA_1c03140 28e305fd26640d2f13d12b82130e91fb 420 Pfam PF04932 O-Antigen ligase 184 331 1.1E-12 T 12-10-2018 IPR007016 O-antigen ligase-related VAPA_1c19850 2beb4690363ca976ba29c380bdf14acd 93 SUPERFAMILY SSF56349 7 83 1.41E-12 T 12-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 VAPA_1c19850 2beb4690363ca976ba29c380bdf14acd 93 Gene3D G3DSA:1.10.443.10 9 89 2.5E-5 T 12-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 VAPA_1c26250 34113db6379205fe5727e00ba61c4d22 436 Pfam PF02653 Branched-chain amino acid transport system / permease component 44 317 4.7E-26 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 VAPA_1c41320 ca6beee3f8677acba980e07d46f4ba69 68 Pfam PF04328 Selenoprotein, putative 10 68 1.2E-27 T 12-10-2018 IPR007423 Selenoprotein, putative VAPA_1c09210 078d1469403f272214fe80496f5b45af 246 Pfam PF11227 Protein of unknown function (DUF3025) 47 245 1.0E-73 T 12-10-2018 IPR021390 Protein of unknown function DUF3025 VAPA_2c00770 a6ec880effd3e62aa62b1c7a450c40da 171 Gene3D G3DSA:2.40.160.20 21 171 7.5E-41 T 12-10-2018 VAPA_2c00770 a6ec880effd3e62aa62b1c7a450c40da 171 Pfam PF11578 Protein of unknown function (DUF3237) 26 164 1.2E-31 T 12-10-2018 IPR020915 Uncharacterised protein family UPF0311 VAPA_2c00770 a6ec880effd3e62aa62b1c7a450c40da 171 Hamap MF_00775 UPF0311 protein . 24 171 23.212 T 12-10-2018 IPR020915 Uncharacterised protein family UPF0311 VAPA_2c03660 e2ccf824bd90704afb37f8daa8e6e3e7 293 Pfam PF02653 Branched-chain amino acid transport system / permease component 9 280 3.5E-40 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 VAPA_1c46680 1c76243326de59f3783fd68228c59d4c 509 Pfam PF01970 Tripartite tricarboxylate transporter TctA family 21 439 1.8E-138 T 12-10-2018 IPR002823 Protein of unknown function DUF112, transmembrane VAPA_1c40310 3d4a0613cc5c3372cdd500a4fb16f082 417 Pfam PF01566 Natural resistance-associated macrophage protein 28 390 6.9E-91 T 12-10-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 VAPA_2c10600 ac3b0b3a199c3d92b7b1de08552fd46a 133 Pfam PF07681 DoxX 17 91 1.0E-11 T 12-10-2018 IPR032808 DoxX family VAPA_1c45610 68678994fb43618b50ea3044fb96023c 69 Pfam PF11174 Protein of unknown function (DUF2970) 12 67 2.1E-22 T 12-10-2018 IPR021344 Protein of unknown function DUF2970 VAPA_2c02290 71b9b1d19ad3e791214e07ff3774fa59 624 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 209 617 4.3E-87 T 12-10-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit VAPA_2c02290 71b9b1d19ad3e791214e07ff3774fa59 624 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 42 169 2.8E-30 T 12-10-2018 IPR007387 TRAP transporter, small membrane protein DctQ VAPA_1c45200 08cefee4f44fc57d55a454e9b637d6c4 316 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 114 312 7.4E-41 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 VAPA_1c45200 08cefee4f44fc57d55a454e9b637d6c4 316 SUPERFAMILY SSF161098 90 298 8.67E-22 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c45200 08cefee4f44fc57d55a454e9b637d6c4 316 Gene3D G3DSA:1.10.3720.10 84 307 1.1E-25 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c18400 b2f84168881e2158e4196cb0b3bd93b4 248 SUPERFAMILY SSF52833 13 221 3.2E-35 T 12-10-2018 IPR036249 Thioredoxin-like superfamily VAPA_1c18400 b2f84168881e2158e4196cb0b3bd93b4 248 Pfam PF01323 DSBA-like thioredoxin domain 15 194 4.2E-11 T 12-10-2018 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590|Reactome: R-HSA-9033241 VAPA_1c18400 b2f84168881e2158e4196cb0b3bd93b4 248 Gene3D G3DSA:3.40.30.10 11 223 9.0E-53 T 12-10-2018 VAPA_1c52670 9e57695b5c13a8dc59d905b4fb3f5bb1 265 Pfam PF09916 Uncharacterized protein conserved in bacteria (DUF2145) 50 250 3.5E-79 T 12-10-2018 IPR014547 Uncharacterised conserved protein UCP028477 VAPA_1c27210 fb2cb25095669617fe5a240b84a6982d 194 Pfam PF01814 Hemerythrin HHE cation binding domain 5 141 2.5E-15 T 12-10-2018 IPR012312 Haemerythrin-like Reactome: R-HSA-390471|Reactome: R-HSA-8951664|Reactome: R-HSA-917937|Reactome: R-HSA-983168 VAPA_1c27210 fb2cb25095669617fe5a240b84a6982d 194 Gene3D G3DSA:1.20.120.520 1 162 6.3E-30 T 12-10-2018 VAPA_1c04720 e5e2856b225a466ce02ade3429c4376f 334 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 114 334 1.8E-46 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 VAPA_1c04720 e5e2856b225a466ce02ade3429c4376f 334 SUPERFAMILY SSF161098 91 321 5.78E-19 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c12130 33168fa1c51ac0a724ecccb5ac31675b 286 Pfam PF00005 ABC transporter 39 187 8.5E-26 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 VAPA_1c12130 33168fa1c51ac0a724ecccb5ac31675b 286 ProSitePatterns PS00211 ABC transporters family signature. 159 173 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 VAPA_1c12130 33168fa1c51ac0a724ecccb5ac31675b 286 SMART SM00382 47 236 4.9E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain VAPA_1c12130 33168fa1c51ac0a724ecccb5ac31675b 286 Gene3D G3DSA:3.40.50.300 21 267 1.2E-65 T 12-10-2018 VAPA_1c12130 33168fa1c51ac0a724ecccb5ac31675b 286 SUPERFAMILY SSF52540 21 249 9.44E-64 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c10160 d0da1293395b73c9290d497e21df486c 298 Pfam PF09414 RNA ligase 45 228 1.2E-29 T 12-10-2018 IPR021122 RNA ligase domain, REL/Rln2 VAPA_1c10160 d0da1293395b73c9290d497e21df486c 298 SUPERFAMILY SSF56091 13 242 4.32E-38 T 12-10-2018 VAPA_1c10160 d0da1293395b73c9290d497e21df486c 298 Gene3D G3DSA:3.30.470.30 32 237 3.1E-19 T 12-10-2018 VAPA_1c03640 6b13af1eccd8619e68619623a6c7901b 388 Pfam PF02405 Permease MlaE 172 379 3.1E-68 T 12-10-2018 IPR030802 ABC transporter permease MalE GO:0043190 VAPA_1c03640 6b13af1eccd8619e68619623a6c7901b 388 TIGRFAM TIGR00056 TIGR00056: ABC transport permease subunit 166 381 9.1E-67 T 12-10-2018 IPR003453 ABC transport permease subunit MlaE, Proteobacteria VAPA_1c06950 47702ec841ac229487bb30c85a05df17 305 SUPERFAMILY SSF75005 22 296 2.24E-12 T 12-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily VAPA_1c53630 3c9a15d9f7de926e2c7add98d1d10a11 154 Pfam PF12512 Protein of unknown function (DUF3717) 3 68 3.3E-28 T 12-10-2018 IPR022191 Protein of unknown function DUF3717 VAPA_1c53630 3c9a15d9f7de926e2c7add98d1d10a11 154 Pfam PF06945 Protein of unknown function (DUF1289) 73 117 4.0E-17 T 12-10-2018 IPR010710 Protein of unknown function DUF1289 VAPA_1c07100 67805c9615ab8ff4b1937231d06b3f4d 144 Pfam PF13340 Putative transposase of IS4/5 family (DUF4096) 10 86 5.0E-24 T 12-10-2018 IPR025161 Putative transposase IS4/IS5 family VAPA_1c06160 98bef02a1222f4d17df35c732dc174a0 347 SUPERFAMILY SSF53901 68 337 3.92E-13 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 VAPA_1c06160 98bef02a1222f4d17df35c732dc174a0 347 Gene3D G3DSA:3.40.47.10 16 204 9.7E-10 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 VAPA_1c34200 1d7cbd559f1999b168325ce99f61c927 227 Pfam PF01323 DSBA-like thioredoxin domain 9 213 2.2E-34 T 12-10-2018 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590|Reactome: R-HSA-9033241 VAPA_1c34200 1d7cbd559f1999b168325ce99f61c927 227 SUPERFAMILY SSF52833 7 217 7.65E-49 T 12-10-2018 IPR036249 Thioredoxin-like superfamily VAPA_1c34200 1d7cbd559f1999b168325ce99f61c927 227 Gene3D G3DSA:3.40.30.10 2 217 1.2E-66 T 12-10-2018 VAPA_1c46990 c04ce8039bdc74b77f443fb4f6220cba 182 Pfam PF06210 Protein of unknown function (DUF1003) 65 158 2.3E-36 T 12-10-2018 IPR010406 Protein of unknown function DUF1003 VAPA_1c09580 9bde1b80c2469b0107621b2d44d90cc5 488 Pfam PF06097 Bacterial protein of unknown function (DUF945) 3 483 6.8E-69 T 12-10-2018 IPR010352 Protein of unknown function DUF945 VAPA_2c10540 315a65207e5584bc0967dc7650bace5f 234 Pfam PF06912 Protein of unknown function (DUF1275) 7 216 8.1E-30 T 12-10-2018 IPR010699 Protein of unknown function DUF1275 VAPA_1c13220 100db2bf4df43080997fda7ceda6f9ab 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 4.7E-21 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c13220 100db2bf4df43080997fda7ceda6f9ab 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 4.7E-21 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c13220 100db2bf4df43080997fda7ceda6f9ab 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 4.7E-21 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c13220 100db2bf4df43080997fda7ceda6f9ab 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 4.7E-21 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c13220 100db2bf4df43080997fda7ceda6f9ab 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 222 242 4.7E-21 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR VAPA_1c13220 100db2bf4df43080997fda7ceda6f9ab 263 SUPERFAMILY SSF51735 7 258 3.4E-56 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c13220 100db2bf4df43080997fda7ceda6f9ab 263 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 257 5.1E-38 T 12-10-2018 VAPA_1c13220 100db2bf4df43080997fda7ceda6f9ab 263 Gene3D G3DSA:3.40.50.720 1 263 8.9E-59 T 12-10-2018 VAPA_2c07480 fd40304439e3556ba00bf0aaaaf90c54 174 Pfam PF14434 Immunity protein Imm6 16 127 1.2E-8 T 12-10-2018 IPR025674 Immunity protein Imm6 VAPA_2c07110 954fe9e0de52bb0e2a8ef132e6f37390 466 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 43 457 1.2E-83 T 12-10-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit VAPA_2c07110 954fe9e0de52bb0e2a8ef132e6f37390 466 TIGRFAM TIGR00786 dctM: TRAP transporter, DctM subunit 53 462 1.1E-96 T 12-10-2018 IPR004681 TRAP transporter large membrane protein DctM GO:0016021 VAPA_2c07110 954fe9e0de52bb0e2a8ef132e6f37390 466 PIRSF PIRSF006066 37 466 4.2E-86 T 12-10-2018 IPR004681 TRAP transporter large membrane protein DctM GO:0016021 VAPA_1c50200 5e091a2384f57d4b27adbc80fd73fb58 310 Pfam PF02653 Branched-chain amino acid transport system / permease component 16 280 6.2E-35 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 VAPA_1c01500 03f9a687ec0411fba58793cd7a6b1aef 441 Pfam PF02133 Permease for cytosine/purines, uracil, thiamine, allantoin 19 417 4.0E-19 T 12-10-2018 IPR001248 Purine-cytosine permease GO:0016020|GO:0022857|GO:0055085 VAPA_1c01500 03f9a687ec0411fba58793cd7a6b1aef 441 Gene3D G3DSA:1.10.4160.10 11 431 3.0E-35 T 12-10-2018 IPR038271 Purine-cytosine permease superfamily VAPA_1c04580 17befdb6dc652301cd3f28459fce97a8 662 SMART SM00387 563 657 4.2E-5 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase VAPA_1c04580 17befdb6dc652301cd3f28459fce97a8 662 Gene3D G3DSA:3.30.565.10 534 656 4.0E-24 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_1c04580 17befdb6dc652301cd3f28459fce97a8 662 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 567 656 1.6E-5 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase VAPA_1c04580 17befdb6dc652301cd3f28459fce97a8 662 SUPERFAMILY SSF55874 527 655 3.54E-16 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily VAPA_1c09500 db902a805a9fa9b0f78adefa1d9d330c 125 Pfam PF11720 Peptidase inhibitor I78 family 61 125 2.2E-7 T 12-10-2018 IPR021719 Proteinase inhibitor I78 VAPA_1c09500 db902a805a9fa9b0f78adefa1d9d330c 125 Gene3D G3DSA:3.30.10.10 57 124 5.3E-8 T 12-10-2018 VAPA_1c52040 cd11abb67a48e0e65b2701a4daba2655 431 Pfam PF13701 Transposase DDE domain group 1 8 429 5.3E-149 T 12-10-2018 IPR025668 Transposase DDE domain VAPA_2c12180 89ea674eb885a320fd65bb5f2bdc286a 537 Pfam PF00665 Integrase core domain 139 264 9.4E-15 T 12-10-2018 IPR001584 Integrase, catalytic core GO:0015074 VAPA_1c43860 1e26246043e9cebccf8cedc327599da9 648 Pfam PF01757 Acyltransferase family 7 332 1.1E-26 T 12-10-2018 IPR002656 Acyltransferase 3 GO:0016747 VAPA_1c08410 0195790bd70d817152dbc225497b60ed 271 Pfam PF09948 Predicted metal-binding integral membrane protein (DUF2182) 78 265 7.4E-62 T 12-10-2018 IPR018688 Protein of unknown function DUF2182, transmembrane, metal-binding VAPA_2c02300 befe65ab2e34bffb5faaeb034794055a 244 Pfam PF08843 Nucleotidyl transferase AbiEii toxin, Type IV TA system 20 183 7.0E-13 T 12-10-2018 IPR014942 Nucleotidyl transferase AbiEii toxin, Type IV TA system VAPA_1c17360 397e8adef138957c6f571f9078298c5d 293 Pfam PF07264 Etoposide-induced protein 2.4 (EI24) 8 218 3.0E-22 T 12-10-2018 VAPA_1c34800 33076dd3fa3e4e654e269ca123b31df4 385 Pfam PF12698 ABC-2 family transporter protein 23 377 6.2E-26 T 12-10-2018 VAPA_1c50230 49843e5d13746278ef8db25ba6c09474 348 Pfam PF13343 Bacterial extracellular solute-binding protein 85 315 1.6E-31 T 12-10-2018 VAPA_1c50230 49843e5d13746278ef8db25ba6c09474 348 SUPERFAMILY SSF53850 34 346 3.26E-57 T 12-10-2018 VAPA_1c50230 49843e5d13746278ef8db25ba6c09474 348 Gene3D G3DSA:3.40.190.10 50 314 1.3E-73 T 12-10-2018 VAPA_1c50230 49843e5d13746278ef8db25ba6c09474 348 Gene3D G3DSA:3.40.190.10 138 343 1.3E-73 T 12-10-2018 VAPA_1c44870 8ca552a7a2f98f6a6079c8c7a25feb02 553 Pfam PF10544 T5orf172 domain 448 537 2.7E-12 T 12-10-2018 IPR018306 Bacteriophage T5, Orf172 DNA-binding VAPA_1c44870 8ca552a7a2f98f6a6079c8c7a25feb02 553 SMART SM00974 457 537 2.4E-11 T 12-10-2018 IPR018306 Bacteriophage T5, Orf172 DNA-binding VAPA_1c45350 2717bd8f01355467655d268638ccd004 213 Pfam PF06930 Protein of unknown function (DUF1282) 10 174 6.4E-18 T 12-10-2018 IPR009698 Protein of unknown function DUF1282 VAPA_1c39240 0794ca80dea62fce95d0f2541f084ef6 309 Gene3D G3DSA:2.120.10.30 1 296 7.3E-62 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like VAPA_1c39240 0794ca80dea62fce95d0f2541f084ef6 309 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 269 287 4.4E-9 T 12-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) VAPA_1c39240 0794ca80dea62fce95d0f2541f084ef6 309 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 179 199 4.4E-9 T 12-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) VAPA_1c39240 0794ca80dea62fce95d0f2541f084ef6 309 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 156 178 4.4E-9 T 12-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) VAPA_1c39240 0794ca80dea62fce95d0f2541f084ef6 309 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 227 244 4.4E-9 T 12-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) VAPA_1c39240 0794ca80dea62fce95d0f2541f084ef6 309 Pfam PF08450 SMP-30/Gluconolaconase/LRE-like region 12 286 4.5E-53 T 12-10-2018 IPR013658 SMP-30/Gluconolactonase/LRE-like region VAPA_1c39240 0794ca80dea62fce95d0f2541f084ef6 309 SUPERFAMILY SSF63829 3 304 2.45E-55 T 12-10-2018 VAPA_1c19820 af61ab2c5a2976d3804f1527bff2c2dc 149 Pfam PF14384 BrnA antitoxin of type II toxin-antitoxin system 25 80 9.6E-18 T 12-10-2018 IPR025528 BrnA antitoxin of type II toxin-antitoxin system VAPA_1c15430 79b749365ccbd8e834217d3cdfbd9901 105 Pfam PF03692 Putative zinc- or iron-chelating domain 3 83 1.1E-6 T 12-10-2018 IPR005358 Putative zinc- or iron-chelating domain containing protein VAPA_1c31170 5c7f26681056daa8ff45edf7965cdf76 183 Gene3D G3DSA:1.25.40.10 62 172 2.8E-7 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 VAPA_1c31170 5c7f26681056daa8ff45edf7965cdf76 183 SUPERFAMILY SSF48452 64 161 1.94E-6 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 VAPA_1c29950 4e671ec81b9c0fb19c52e00a0f2efd2b 243 Pfam PF04172 LrgB-like family 25 238 4.5E-77 T 12-10-2018 IPR007300 CidB/LrgB family VAPA_1c39510 625c5d443548714d7279af6d518f662f 73 Pfam PF06348 Protein of unknown function (DUF1059) 6 53 1.5E-10 T 12-10-2018 IPR009409 Protein of unknown function DUF1059 VAPA_1c17970 3b4d72d4aca4c1735123bf29422e198a 430 Hamap MF_01232 UPF0229 protein YeaH [yeaH]. 3 428 36.544 T 12-10-2018 IPR006698 Uncharacterised protein family UPF0229 VAPA_1c17970 3b4d72d4aca4c1735123bf29422e198a 430 Pfam PF04285 Protein of unknown function (DUF444) 6 426 8.3E-174 T 12-10-2018 IPR006698 Uncharacterised protein family UPF0229 VAPA_1c43170 3158cfdf042b04198ff80a8f9cbc3c70 94 SUPERFAMILY SSF160544 6 86 1.23E-21 T 12-10-2018 IPR029025 Type III secretion system substrate exporter, C-terminal VAPA_1c43170 3158cfdf042b04198ff80a8f9cbc3c70 94 Pfam PF01312 FlhB HrpN YscU SpaS Family 7 82 8.0E-18 T 12-10-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 VAPA_1c43170 3158cfdf042b04198ff80a8f9cbc3c70 94 Gene3D G3DSA:3.40.1690.10 7 87 3.7E-22 T 12-10-2018 IPR029025 Type III secretion system substrate exporter, C-terminal VAPA_2c07120 878d6b52b74acecfb8234e878ae11e3a 206 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 23 155 5.1E-17 T 12-10-2018 IPR007387 TRAP transporter, small membrane protein DctQ VAPA_1c50440 4a2665c8d560bf03c4b20029f47665bc 175 Pfam PF12276 Protein of unknown function (DUF3617) 2 147 1.9E-8 T 12-10-2018 IPR022061 Protein of unknown function DUF3617 VAPA_1c14580 3508371edbe80eef78bd7102c5b3983e 457 Gene3D G3DSA:2.40.160.10 7 456 6.8E-135 T 12-10-2018 IPR023614 Porin domain superfamily VAPA_1c14580 3508371edbe80eef78bd7102c5b3983e 457 Pfam PF03573 outer membrane porin, OprD family 40 455 9.5E-120 T 12-10-2018 IPR005318 Outer membrane porin, bacterial GO:0016021 VAPA_1c48570 17b5148edebf10f1315caccfded4ecec 368 SUPERFAMILY SSF53822 23 367 5.97E-71 T 12-10-2018 IPR028082 Periplasmic binding protein-like I VAPA_1c48570 17b5148edebf10f1315caccfded4ecec 368 Gene3D G3DSA:3.40.50.2300 23 357 1.2E-107 T 12-10-2018 VAPA_1c48570 17b5148edebf10f1315caccfded4ecec 368 Gene3D G3DSA:3.40.50.2300 142 361 1.2E-107 T 12-10-2018 VAPA_1c48570 17b5148edebf10f1315caccfded4ecec 368 Pfam PF13458 Periplasmic binding protein 22 353 6.5E-59 T 12-10-2018 IPR028081 Leucine-binding protein domain VAPA_1c48570 17b5148edebf10f1315caccfded4ecec 368 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 64 82 9.2E-6 T 12-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 VAPA_1c48570 17b5148edebf10f1315caccfded4ecec 368 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 251 269 9.2E-6 T 12-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 VAPA_1c48570 17b5148edebf10f1315caccfded4ecec 368 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 45 61 9.2E-6 T 12-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 VAPA_2c10970 9105700703dea99c59f1f7d7a4f34b10 265 SUPERFAMILY SSF49354 26 155 4.45E-16 T 12-10-2018 IPR008962 PapD-like superfamily VAPA_2c10970 9105700703dea99c59f1f7d7a4f34b10 265 Gene3D G3DSA:2.60.40.10 31 156 2.6E-6 T 12-10-2018 IPR013783 Immunoglobulin-like fold VAPA_2c10970 9105700703dea99c59f1f7d7a4f34b10 265 Pfam PF00345 Pili and flagellar-assembly chaperone, PapD N-terminal domain 31 155 2.8E-17 T 12-10-2018 IPR016147 Pili assembly chaperone, N-terminal GO:0030288|GO:0071555 VAPA_1c45090 398fa1f9c91d847ae5499a1a6c7cc0cc 654 SUPERFAMILY SSF52540 34 324 2.47E-21 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c45090 398fa1f9c91d847ae5499a1a6c7cc0cc 654 Pfam PF00350 Dynamin family 58 274 4.1E-14 T 12-10-2018 IPR022812 Dynamin superfamily VAPA_1c37940 b4930270b179d312379c231a87b4684b 194 Pfam PF07273 Protein of unknown function (DUF1439) 45 155 4.5E-7 T 12-10-2018 IPR010835 Protein of unknown function DUF1439 VAPA_1c31660 18e4148a6ce9ef94f3e400ed8cac7b14 1270 Pfam PF05359 Domain of Unknown Function (DUF748) 148 298 2.9E-20 T 12-10-2018 IPR008023 Protein of unknown function DUF748 VAPA_1c31660 18e4148a6ce9ef94f3e400ed8cac7b14 1270 Pfam PF05359 Domain of Unknown Function (DUF748) 588 728 5.4E-18 T 12-10-2018 IPR008023 Protein of unknown function DUF748 VAPA_1c31660 18e4148a6ce9ef94f3e400ed8cac7b14 1270 Pfam PF05359 Domain of Unknown Function (DUF748) 370 501 4.4E-17 T 12-10-2018 IPR008023 Protein of unknown function DUF748 VAPA_1c31660 18e4148a6ce9ef94f3e400ed8cac7b14 1270 Pfam PF05359 Domain of Unknown Function (DUF748) 872 1019 1.7E-31 T 12-10-2018 IPR008023 Protein of unknown function DUF748 VAPA_1c41090 d49cd95f2d9f01571b697991531fa5cc 84 Pfam PF09791 Oxidoreductase-like protein, N-terminal 36 69 2.8E-10 T 12-10-2018 IPR019180 Oxidoreductase-like, N-terminal VAPA_2c01920 6251b376521cd02ef419b5a75ff68a7b 256 Pfam PF01925 Sulfite exporter TauE/SafE 12 243 2.8E-23 T 12-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 VAPA_2c06660 bedada406338c593805b22caa6c6f8c4 342 Pfam PF02653 Branched-chain amino acid transport system / permease component 56 329 1.1E-51 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 VAPA_2c13300 68eb5e3adb401fe2e47c42222e613ea1 122 Pfam PF05101 Type IV secretory pathway, VirB3-like protein 9 94 9.7E-25 T 12-10-2018 IPR007792 Type IV secretion system, VirB3 / TrbD / AvhB VAPA_1c22960 3916c20ced669ac34f1887d028c78e7a 158 SUPERFAMILY SSF55729 6 141 2.66E-21 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase VAPA_1c22960 3916c20ced669ac34f1887d028c78e7a 158 Gene3D G3DSA:3.40.630.30 4 152 3.1E-17 T 12-10-2018 VAPA_1c22960 3916c20ced669ac34f1887d028c78e7a 158 Pfam PF13673 Acetyltransferase (GNAT) domain 57 142 1.8E-9 T 12-10-2018 IPR000182 GNAT domain VAPA_1c39790 e19a229e8132c93d92751390d6920312 358 Pfam PF13503 Domain of unknown function (DUF4123) 72 186 5.4E-12 T 12-10-2018 IPR025391 Domain of unknown function DUF4123 VAPA_1c47350 bedbcd6d71d4066b9341038f5effeaf5 215 Gene3D G3DSA:1.10.150.130 10 44 5.5E-6 T 12-10-2018 IPR010998 Integrase/recombinase, N-terminal VAPA_1c47350 bedbcd6d71d4066b9341038f5effeaf5 215 SUPERFAMILY SSF56349 18 120 8.47E-8 T 12-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 VAPA_1c02040 63a6370c5724c50da425847a1016e5c1 277 Gene3D G3DSA:2.30.30.40 23 88 7.8E-10 T 12-10-2018 VAPA_1c02040 63a6370c5724c50da425847a1016e5c1 277 Pfam PF08239 Bacterial SH3 domain 34 86 7.9E-12 T 12-10-2018 IPR003646 SH3-like domain, bacterial-type VAPA_2c01680 38efbe57adf3f25b1227ed612cc63e84 287 Pfam PF03741 Integral membrane protein TerC family 54 241 3.1E-49 T 12-10-2018 IPR005496 Integral membrane protein TerC GO:0016021 VAPA_1c45580 953d01556dac8435d95038acd43f37b4 269 Pfam PF02104 SURF1 family 29 241 1.7E-35 T 12-10-2018 IPR002994 Surfeit locus 1/Shy1 GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 VAPA_1c41650 dc32d8603942936d8bc5df2e1cc548b8 355 Pfam PF10503 Esterase PHB depolymerase 75 267 6.5E-50 T 12-10-2018 IPR010126 Esterase, PHB depolymerase GO:0005576|GO:0016787 VAPA_1c41650 dc32d8603942936d8bc5df2e1cc548b8 355 SUPERFAMILY SSF53474 62 290 5.4E-32 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c41650 dc32d8603942936d8bc5df2e1cc548b8 355 Gene3D G3DSA:3.40.50.1820 58 342 9.9E-41 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold VAPA_1c11030 ad89607eefca66332d3346e002cd8b1c 343 Pfam PF02653 Branched-chain amino acid transport system / permease component 61 329 2.7E-42 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 VAPA_1c45000 ce17336fd06f58d3cf0cdf456144a281 375 SUPERFAMILY SSF52540 2 196 1.19E-7 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_2c03190 eff204ad6f906f569eb61f529834588b 118 Pfam PF13665 Domain of unknown function (DUF4150) 15 117 1.6E-34 T 12-10-2018 IPR025425 Domain of unknown function DUF4150 VAPA_2c01010 ec80470237670d5ba114e4f34c9f3459 270 Pfam PF13649 Methyltransferase domain 43 134 2.2E-23 T 12-10-2018 VAPA_2c01010 ec80470237670d5ba114e4f34c9f3459 270 SUPERFAMILY SSF53335 16 216 8.67E-41 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase VAPA_2c01010 ec80470237670d5ba114e4f34c9f3459 270 Gene3D G3DSA:3.40.50.150 4 251 3.3E-40 T 12-10-2018 VAPA_2c07920 2aefa54529840dc4f2dc817ba0d28615 124 Pfam PF04304 Protein of unknown function (DUF454) 9 123 2.5E-35 T 12-10-2018 IPR007401 Protein of unknown function DUF454 VAPA_2c07920 2aefa54529840dc4f2dc817ba0d28615 124 PIRSF PIRSF016789 8 124 5.6E-31 T 12-10-2018 IPR007401 Protein of unknown function DUF454 VAPA_1c18790 5a853a9be5a950d1c4fa694910f81b44 82 Pfam PF04226 Transglycosylase associated protein 33 80 9.6E-12 T 12-10-2018 IPR007341 Transglycosylase-associated protein GO:0016021 VAPA_2c04970 df7ed226929700c59dfde4056cd7a448 69 Pfam PF11127 Protein of unknown function (DUF2892) 6 61 9.3E-11 T 12-10-2018 IPR021309 Protein of unknown function DUF2892 VAPA_1c09830 ea53642b02a28e6a506a61b5eb46ab33 329 Pfam PF01148 Cytidylyltransferase family 62 323 5.8E-25 T 12-10-2018 VAPA_1c34050 9ac9e7951868da6958900fb5e87e99e4 164 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 30 153 3.8E-28 T 12-10-2018 IPR007387 TRAP transporter, small membrane protein DctQ VAPA_1c54480 2b1230b0452136bb386c11efbdf29b2b 126 Pfam PF13564 DoxX-like family 19 111 3.5E-16 T 12-10-2018 IPR032808 DoxX family VAPA_1c39320 89d560b064bb91ebcf2dac9b9a485300 391 Pfam PF04295 D-galactarate dehydratase / Altronate hydrolase, C terminus 9 387 2.6E-127 T 12-10-2018 IPR007392 D-galactarate/Altronate dehydratase, C-terminal GO:0016829 VAPA_1c16770 6766126994a8a1863a1446761d1e97c3 286 Pfam PF02653 Branched-chain amino acid transport system / permease component 9 276 8.5E-37 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 VAPA_1c23940 a397c69c023721b2e876b0ba69687052 196 Pfam PF02417 Chromate transporter 22 186 4.7E-30 T 12-10-2018 IPR003370 Chromate transporter GO:0015109|GO:0015703 VAPA_1c24860 0d1b6e1a44427a955c434178100ca3ff 262 Pfam PF04116 Fatty acid hydroxylase superfamily 105 234 1.0E-22 T 12-10-2018 IPR006694 Fatty acid hydroxylase GO:0005506|GO:0008610|GO:0016491|GO:0055114 VAPA_2c12140 0d79bae002b3b9812588d1d86cc031e4 488 Pfam PF01609 Transposase DDE domain 234 444 1.6E-10 T 12-10-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 VAPA_2c12140 0d79bae002b3b9812588d1d86cc031e4 488 Pfam PF05598 Transposase domain (DUF772) 56 123 2.0E-17 T 12-10-2018 IPR008490 Transposase InsH, N-terminal VAPA_1c10700 def17ba9cf0557561e8ce64495613012 211 Gene3D G3DSA:3.40.50.12500 1 209 2.3E-16 T 12-10-2018 VAPA_2c06500 febbea659c457bc0bd8a4b36396b6555 155 Pfam PF10029 Predicted periplasmic protein (DUF2271) 24 149 1.7E-34 T 12-10-2018 IPR014469 Protein of unknown function DUF2271 VAPA_1c54410 f729b56e1a2c0953421e996c7a2e5131 323 Gene3D G3DSA:3.40.50.720 29 323 7.7E-101 T 12-10-2018 VAPA_1c54410 f729b56e1a2c0953421e996c7a2e5131 323 SUPERFAMILY SSF52283 48 121 3.91E-6 T 12-10-2018 VAPA_1c54410 f729b56e1a2c0953421e996c7a2e5131 323 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 115 288 1.3E-42 T 12-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 VAPA_1c54410 f729b56e1a2c0953421e996c7a2e5131 323 Gene3D G3DSA:3.40.50.720 105 289 7.7E-101 T 12-10-2018 VAPA_1c54410 f729b56e1a2c0953421e996c7a2e5131 323 SUPERFAMILY SSF51735 107 288 1.88E-43 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily VAPA_1c40570 4e259a147864d376208676c589c6fa5f 181 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 24 151 2.7E-26 T 12-10-2018 IPR007387 TRAP transporter, small membrane protein DctQ VAPA_1c28970 2313ecb5a092c0cc08709f433625c1c6 286 Pfam PF04116 Fatty acid hydroxylase superfamily 93 227 3.0E-29 T 12-10-2018 IPR006694 Fatty acid hydroxylase GO:0005506|GO:0008610|GO:0016491|GO:0055114 VAPA_1c28900 8596a2e92ed2f2253d565420a013e72c 307 Pfam PF02653 Branched-chain amino acid transport system / permease component 17 285 4.5E-36 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 VAPA_1c23320 8aff77f6595a7c7b9f44169b9f93297a 240 Pfam PF07332 Putative Actinobacterial Holin-X, holin superfamily III 19 128 1.0E-8 T 12-10-2018 IPR009937 Putative Actinobacterial Holin-X, holin superfamily III VAPA_1c06110 dba38047c4fe5ab20a8a51739c6110a8 226 Pfam PF12059 Protein of unknown function (DUF3540) 47 226 7.2E-41 T 12-10-2018 IPR021927 Protein of unknown function DUF3540 VAPA_1c11660 79ca138f500b26d2c477dae19c1e5877 274 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 90 259 1.0E-15 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 VAPA_1c11660 79ca138f500b26d2c477dae19c1e5877 274 SUPERFAMILY SSF161098 5 274 3.46E-61 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c11660 79ca138f500b26d2c477dae19c1e5877 274 Gene3D G3DSA:1.10.3720.10 2 266 4.1E-47 T 12-10-2018 IPR035906 MetI-like superfamily VAPA_1c28960 2cea6b2326e65792ab43aff65b520d73 96 Gene3D G3DSA:1.10.238.10 25 89 1.2E-6 T 12-10-2018 VAPA_1c28960 2cea6b2326e65792ab43aff65b520d73 96 SUPERFAMILY SSF47473 28 86 4.61E-5 T 12-10-2018 IPR011992 EF-hand domain pair VAPA_1c12000 6dbf0fe26ed0037bb3f5cdef01b50960 206 Pfam PF05137 Fimbrial assembly protein (PilN) 100 181 1.7E-23 T 12-10-2018 IPR007813 Fimbrial assembly PilN VAPA_1c26860 c249c81e599964a7b9a1033067950725 223 Pfam PF12059 Protein of unknown function (DUF3540) 41 223 8.3E-53 T 12-10-2018 IPR021927 Protein of unknown function DUF3540 VAPA_1c04660 209021b18f14cb81557a45a5d00814c0 144 Pfam PF13211 Protein of unknown function (DUF4019) 37 141 3.0E-22 T 12-10-2018 IPR025091 Protein of unknown function DUF4019 VAPA_1c45430 34985aa8a92c0d845061a7faa168d0ce 211 Pfam PF01810 LysE type translocator 19 205 3.2E-30 T 12-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 VAPA_1c20600 347114174ed99501cee15d02e3706ac7 32 Pfam PF12664 Protein of unknown function (DUF3789) 7 29 3.1E-7 T 12-10-2018 IPR024522 Protein of unknown function DUF3789 VAPA_1c16110 53b34b32f5d8bc147de7b8675f51a563 152 Pfam PF08388 Group II intron, maturase-specific domain 31 99 1.6E-14 T 12-10-2018 IPR013597 Group II intron, maturase-specific VAPA_1c50050 25c64ff292696d3d3a32044deba90758 183 Pfam PF11161 Protein of unknown function (DUF2946) 1 173 2.6E-65 T 12-10-2018 IPR021332 Protein of unknown function DUF2944 VAPA_1c35550 cd2db329d294ee33775061a57bb3efda 207 Pfam PF04973 Nicotinamide mononucleotide transporter 18 197 6.7E-50 T 12-10-2018 IPR006419 Nicotinamide mononucleotide transporter PnuC GO:0016020|GO:0034257|GO:0034258 VAPA_1c35550 cd2db329d294ee33775061a57bb3efda 207 TIGRFAM TIGR01528 NMN_trans_PnuC: nicotinamide mononucleotide transporter PnuC 18 198 4.9E-26 T 12-10-2018 IPR006419 Nicotinamide mononucleotide transporter PnuC GO:0016020|GO:0034257|GO:0034258 VAPA_2c11640 ee16ab3bd6d6680867be87d3d4776161 100 Gene3D G3DSA:2.40.30.10 7 98 6.7E-5 T 12-10-2018 VAPA_1c42010 42b30003e58fd910a52cddf2b0c15397 74 Pfam PF04102 SlyX 9 74 1.4E-19 T 12-10-2018 IPR007236 SlyX VAPA_2c08050 da45df564bc297c5c4206bbc55c0915c 101 SUPERFAMILY SSF54292 24 94 1.15E-16 T 12-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 VAPA_2c08050 da45df564bc297c5c4206bbc55c0915c 101 Gene3D G3DSA:3.10.20.30 1 100 1.3E-14 T 12-10-2018 IPR012675 Beta-grasp domain superfamily VAPA_2c08050 da45df564bc297c5c4206bbc55c0915c 101 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 34 87 2.8E-8 T 12-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 VAPA_1c27170 3fa0f752c53f319d11223391e81bbbe4 1031 Pfam PF05567 Neisseria PilC beta-propeller domain 549 791 1.4E-10 T 12-10-2018 IPR008707 PilC beta-propeller domain VAPA_1c42780 03d87a678cec163d3d258aaba5c7f55d 206 Pfam PF04367 Protein of unknown function (DUF502) 58 164 6.2E-37 T 12-10-2018 IPR007462 Protein of unknown function DUF502 VAPA_1c04170 4456197f2de25e620583e9bbf8019125 147 SUPERFAMILY SSF54637 4 141 1.94E-39 T 12-10-2018 IPR029069 HotDog domain superfamily VAPA_1c04170 4456197f2de25e620583e9bbf8019125 147 Gene3D G3DSA:3.10.129.10 1 147 6.9E-43 T 12-10-2018 VAPA_1c04170 4456197f2de25e620583e9bbf8019125 147 Pfam PF03061 Thioesterase superfamily 18 92 2.6E-21 T 12-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 VAPA_1c27680 38cdc27c799ef6a4b82a6f5b1fffadd0 523 Pfam PF03929 PepSY-associated TM region 8 484 3.4E-10 T 12-10-2018 IPR005625 PepSY-associated TM protein VAPA_1c32300 9545ba894c31d59215c62cd0a768b3af 402 Pfam PF02653 Branched-chain amino acid transport system / permease component 37 336 1.5E-31 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 VAPA_1c32300 9545ba894c31d59215c62cd0a768b3af 402 TIGRFAM TIGR03408 urea_trans_UrtC: urea ABC transporter, permease protein UrtC 29 347 6.5E-130 T 12-10-2018 IPR017778 ABC transporter, urea, permease protein, UrtC VAPA_2c10880 7ad475427651c342f6cfa98568cab126 221 Gene3D G3DSA:1.20.120.1630 9 209 1.1E-24 T 12-10-2018 VAPA_2c10880 7ad475427651c342f6cfa98568cab126 221 Pfam PF04191 Phospholipid methyltransferase 101 193 1.3E-9 T 12-10-2018 IPR007318 Phospholipid methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825|Reactome: R-HSA-1483191 VAPA_1c52140 443180ee6fad2b4d5ae2c6e65e7525ef 396 Pfam PF02653 Branched-chain amino acid transport system / permease component 46 383 7.2E-36 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 VAPA_2c10480 df20b7986ec4f15ab94dd578e31b7d84 335 SUPERFAMILY SSF51182 208 314 5.87E-7 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily VAPA_2c00310 02e3ad8f21a1f04f4b48e9a2dd27503a 566 SUPERFAMILY SSF48208 224 412 1.09E-15 T 12-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 VAPA_1c10650 b3d2353b0a8ca3564493c1a9403f4c18 95 Pfam PF06080 Protein of unknown function (DUF938) 30 83 1.2E-9 T 12-10-2018 IPR010342 Protein of unknown function DUF938 VAPA_1c53590 6fb556d4a047e7851b6c95ccd852102c 377 Pfam PF03929 PepSY-associated TM region 12 356 6.1E-45 T 12-10-2018 IPR005625 PepSY-associated TM protein VAPA_1c26050 ee47ff78b399819f31b8011ab35be483 131 Pfam PF07681 DoxX 9 89 1.4E-18 T 12-10-2018 IPR032808 DoxX family VAPA_1c41390 c419f946d14653c8da9b9cfb5cbb689f 397 Pfam PF13367 Protease prsW family 87 265 2.5E-30 T 12-10-2018 IPR026898 Protease PrsW GO:0008233 VAPA_1c37430 480c4074ecb040add727629bcfb16549 413 Pfam PF01757 Acyltransferase family 12 366 3.3E-27 T 12-10-2018 IPR002656 Acyltransferase 3 GO:0016747 VAPA_1c53860 0d8b1d42b94fb3fc064f1ac47561f14f 484 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 340 469 1.4E-10 T 12-10-2018 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain VAPA_1c53860 0d8b1d42b94fb3fc064f1ac47561f14f 484 Pfam PF01943 Polysaccharide biosynthesis protein 9 284 3.6E-11 T 12-10-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 VAPA_1c22680 bd05f99aea5b857f131d11cd3b33e6ee 266 SUPERFAMILY SSF56529 3 266 5.34E-72 T 12-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 VAPA_1c22680 bd05f99aea5b857f131d11cd3b33e6ee 266 Gene3D G3DSA:3.90.850.10 1 266 3.0E-76 T 12-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 VAPA_1c22680 bd05f99aea5b857f131d11cd3b33e6ee 266 TIGRFAM TIGR02312 HpaH: 2-oxo-hepta-3-ene-1,7-dioic acid hydratase 1 266 8.9E-135 T 12-10-2018 IPR012690 2-oxo-hepta-4-ene-1,7-dioic acid hydratase GO:0018817|GO:0019439 VAPA_1c47450 ba019375cd66bc328a367dd07d0fd43f 537 Pfam PF00665 Integrase core domain 139 264 9.4E-15 T 12-10-2018 IPR001584 Integrase, catalytic core GO:0015074 VAPA_1c00500 727780c6fc7e880e26123b727d66c544 300 Pfam PF03783 Curli production assembly/transport component CsgG 97 258 3.6E-5 T 12-10-2018 IPR005534 Curli production assembly/transport component CsgG GO:0030288 VAPA_1c36480 8c5a79cb121029b7948ea33c4ac156da 374 Pfam PF04116 Fatty acid hydroxylase superfamily 206 339 2.3E-30 T 12-10-2018 IPR006694 Fatty acid hydroxylase GO:0005506|GO:0008610|GO:0016491|GO:0055114 VAPA_1c34120 412699e0b895fc2c44e9b7aa7fe18669 312 Pfam PF11219 Protein of unknown function (DUF3014) 131 297 2.3E-62 T 12-10-2018 IPR021382 Protein of unknown function DUF3014 VAPA_1c03940 f3378bdf6012821a4891724dbaa9fe51 257 Pfam PF03707 Bacterial signalling protein N terminal repeat 61 115 7.0E-19 T 12-10-2018 IPR005330 MHYT domain VAPA_1c03940 f3378bdf6012821a4891724dbaa9fe51 257 Pfam PF03707 Bacterial signalling protein N terminal repeat 125 182 3.8E-16 T 12-10-2018 IPR005330 MHYT domain VAPA_1c06250 20d54ac118d0d70b73cd0c2ed5da5eef 497 Pfam PF05943 Type VI secretion protein, EvpB/VC_A0108, tail sheath 67 491 3.1E-188 T 12-10-2018 IPR010269 Type VI secretion protein, EvpB/VC_A0108, tail sheath VAPA_1c06250 20d54ac118d0d70b73cd0c2ed5da5eef 497 TIGRFAM TIGR03355 VI_chp_2: type VI secretion protein, EvpB/VC_A0108 family 18 491 9.4E-219 T 12-10-2018 IPR010269 Type VI secretion protein, EvpB/VC_A0108, tail sheath VAPA_1c26980 fef32ccc5325523294b13ece8a5335d8 340 Pfam PF13177 DNA polymerase III, delta subunit 22 187 2.9E-34 T 12-10-2018 VAPA_1c26980 fef32ccc5325523294b13ece8a5335d8 340 SUPERFAMILY SSF52540 17 229 3.29E-38 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VAPA_1c26980 fef32ccc5325523294b13ece8a5335d8 340 Gene3D G3DSA:3.40.50.300 10 189 1.4E-43 T 12-10-2018 VAPA_1c04430 c460aad6adbb6c9113c45e1b77f1101b 306 Pfam PF02653 Branched-chain amino acid transport system / permease component 10 294 2.4E-37 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 VAPA_1c33450 cd47a4f3e68f2bc50ce4b6bba454445e 696 Pfam PF05650 Domain of unknown function (DUF802) 375 427 3.3E-16 T 12-10-2018 IPR008520 Domain of unknown function DUF802 VAPA_1c33450 cd47a4f3e68f2bc50ce4b6bba454445e 696 Pfam PF05650 Domain of unknown function (DUF802) 320 372 1.5E-17 T 12-10-2018 IPR008520 Domain of unknown function DUF802 VAPA_1c08460 c104b3ce54a7e7d2003d2f29be2ef8f5 185 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 40 163 5.3E-23 T 12-10-2018 IPR007387 TRAP transporter, small membrane protein DctQ VAPA_1c28300 50d108a8702cdb8a605d8bf22425b10e 379 Pfam PF03739 Predicted permease YjgP/YjgQ family 9 346 5.4E-45 T 12-10-2018 IPR005495 Permease LptG/LptF-related GO:0016021 VAPA_1c28300 50d108a8702cdb8a605d8bf22425b10e 379 TIGRFAM TIGR04407 LptF_YjgP: LPS export ABC transporter permease LptF 3 346 4.6E-102 T 12-10-2018 IPR030922 LPS export ABC transporter permease LptF GO:0043190|GO:0055085 VAPA_1c11150 48345ccc435c20e945299947e4022ac9 368 Pfam PF01757 Acyltransferase family 20 334 7.9E-19 T 12-10-2018 IPR002656 Acyltransferase 3 GO:0016747 VAPA_1c49420 90ec2f322ff0f539eb9cdde3cb360109 394 Pfam PF01963 TraB family 73 334 4.9E-51 T 12-10-2018 IPR002816 Pheromone shutdown, TraB VAPA_1c16780 55c706d8b7e13a4504f742335504999f 320 Pfam PF02653 Branched-chain amino acid transport system / permease component 26 282 8.6E-44 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 VAPA_1c27780 91f380a5c0c819d346a69d5793e4e603 129 Pfam PF01042 Endoribonuclease L-PSP 12 125 1.2E-21 T 12-10-2018 IPR006175 YjgF/YER057c/UK114 family Reactome: R-HSA-8849175 VAPA_1c27780 91f380a5c0c819d346a69d5793e4e603 129 SUPERFAMILY SSF55298 1 128 4.56E-34 T 12-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 VAPA_1c27780 91f380a5c0c819d346a69d5793e4e603 129 Gene3D G3DSA:3.30.1330.40 5 129 2.7E-33 T 12-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 VAPA_1c19920 7e096b0f654b94850a4a2cb2a33c9fbe 428 PRINTS PR00758 Arsenical pump membrane protein signature 101 125 1.4E-117 T 12-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 VAPA_1c19920 7e096b0f654b94850a4a2cb2a33c9fbe 428 PRINTS PR00758 Arsenical pump membrane protein signature 364 389 1.4E-117 T 12-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 VAPA_1c19920 7e096b0f654b94850a4a2cb2a33c9fbe 428 PRINTS PR00758 Arsenical pump membrane protein signature 217 242 1.4E-117 T 12-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 VAPA_1c19920 7e096b0f654b94850a4a2cb2a33c9fbe 428 PRINTS PR00758 Arsenical pump membrane protein signature 144 168 1.4E-117 T 12-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 VAPA_1c19920 7e096b0f654b94850a4a2cb2a33c9fbe 428 PRINTS PR00758 Arsenical pump membrane protein signature 177 200 1.4E-117 T 12-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 VAPA_1c19920 7e096b0f654b94850a4a2cb2a33c9fbe 428 PRINTS PR00758 Arsenical pump membrane protein signature 278 302 1.4E-117 T 12-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 VAPA_1c19920 7e096b0f654b94850a4a2cb2a33c9fbe 428 PRINTS PR00758 Arsenical pump membrane protein signature 397 421 1.4E-117 T 12-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 VAPA_1c19920 7e096b0f654b94850a4a2cb2a33c9fbe 428 PRINTS PR00758 Arsenical pump membrane protein signature 323 345 1.4E-117 T 12-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 VAPA_1c19920 7e096b0f654b94850a4a2cb2a33c9fbe 428 Pfam PF02040 Arsenical pump membrane protein 4 423 2.2E-153 T 12-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 VAPA_1c19920 7e096b0f654b94850a4a2cb2a33c9fbe 428 TIGRFAM TIGR00935 2a45: arsenite/antimonite efflux pump membrane protein 3 427 4.7E-216 T 12-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 VAPA_2c12670 a369eb9b039b582e5c248bd0befcf62d 270 Gene3D G3DSA:3.40.50.150 11 249 9.2E-38 T 12-10-2018 VAPA_2c12670 a369eb9b039b582e5c248bd0befcf62d 270 SUPERFAMILY SSF53335 11 205 2.05E-38 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase VAPA_2c12670 a369eb9b039b582e5c248bd0befcf62d 270 Pfam PF08241 Methyltransferase domain 45 142 6.5E-20 T 12-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 VAPA_1c45870 00f577abef2d192e2258b12919f6691e 252 Pfam PF01925 Sulfite exporter TauE/SafE 17 245 7.9E-27 T 12-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 VAPA_1c28210 2a3b25cee60e5ef2581dac5d93b31c93 141 Pfam PF01957 NfeD-like C-terminal, partner-binding 7 140 1.3E-6 T 12-10-2018 IPR002810 NfeD-like, C-terminal domain VAPA_1c30730 1b8a39f3cf089043d2ba7469236366c5 504 Pfam PF01970 Tripartite tricarboxylate transporter TctA family 20 441 1.2E-143 T 12-10-2018 IPR002823 Protein of unknown function DUF112, transmembrane VAPA_1c16600 46bbe9bda6900d56b0caa3e205a2308e 192 Pfam PF10986 Protein of unknown function (DUF2796) 33 176 5.0E-35 T 12-10-2018 IPR021253 Protein of unknown function DUF2796 VAPA_2c12460 29a4057335a9e8075d9ad684f0ef2c9a 202 Pfam PF03458 UPF0126 domain 5 78 5.7E-22 T 12-10-2018 IPR005115 Uncharacterised domain UPF0126 VAPA_2c12460 29a4057335a9e8075d9ad684f0ef2c9a 202 Pfam PF03458 UPF0126 domain 91 164 2.2E-18 T 12-10-2018 IPR005115 Uncharacterised domain UPF0126 VAPA_1c01150 14382ca3d6975d00dc2eb0728661bd2c 242 Pfam PF09859 Oxygenase, catalysing oxidative methylation of damaged DNA 70 241 2.6E-86 T 12-10-2018 IPR018655 Protein of unknown function DUF2086 VAPA_1c01150 14382ca3d6975d00dc2eb0728661bd2c 242 Gene3D G3DSA:2.60.120.620 30 238 4.3E-10 T 12-10-2018 VAPA_1c16170 ebbf21cb16f3bac9dd4a0080d265247a 68 Pfam PF04964 Flp/Fap pilin component 15 47 1.4E-9 T 12-10-2018 IPR007047 Flp/Fap pilin component VAPA_1c32960 dbb78790c1811c0d61ab87f7e24930c5 421 Pfam PF01943 Polysaccharide biosynthesis protein 25 268 8.6E-6 T 12-10-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 VAPA_1c35850 577b235c133913789c4d8e9b7a4faa46 883 Pfam PF02687 FtsX-like permease family 305 397 9.3E-7 T 12-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 VAPA_1c35850 577b235c133913789c4d8e9b7a4faa46 883 Pfam PF02687 FtsX-like permease family 780 870 1.7E-10 T 12-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 VAPA_1c42610 7bb50176b85df59b072653acec073377 670 Pfam PF05170 AsmA family 267 545 1.8E-32 T 12-10-2018 IPR007844 AsmA VAPA_1c42610 7bb50176b85df59b072653acec073377 670 Pfam PF05170 AsmA family 15 134 2.3E-16 T 12-10-2018 IPR007844 AsmA VAPA_2c09000 14c04d9fbd67bd999c8559e1e34d4dcb 70 SUPERFAMILY SSF52218 1 58 3.88E-14 T 12-10-2018 IPR029039 Flavoprotein-like superfamily VAPA_2c09000 14c04d9fbd67bd999c8559e1e34d4dcb 70 Gene3D G3DSA:3.40.50.360 1 68 7.2E-16 T 12-10-2018 IPR029039 Flavoprotein-like superfamily VAPA_2c04840 c49251553dffc55d9c9341add62174bb 67 Pfam PF11127 Protein of unknown function (DUF2892) 5 64 1.5E-19 T 12-10-2018 IPR021309 Protein of unknown function DUF2892 VAPA_2c01370 13b99d237b040d4bacc25e213e0f9a91 170 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 23 144 4.3E-33 T 12-10-2018 IPR007387 TRAP transporter, small membrane protein DctQ VAPA_2c05260 6dc2accc4d85ed5deb9b61d3d8cfdb95 336 Gene3D G3DSA:3.40.190.170 33 334 1.9E-63 T 12-10-2018 IPR038404 TRAP transporter solute receptor DctP superfamily VAPA_2c05260 6dc2accc4d85ed5deb9b61d3d8cfdb95 336 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 41 296 5.9E-26 T 12-10-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0030288|GO:0055085 VAPA_2c08370 d6d54584d3556e44e9ae80d962e8571a 373 Pfam PF05935 Arylsulfotransferase (ASST) 38 231 2.0E-10 T 12-10-2018 IPR010262 Arylsulfotransferase, bacteria GO:0004062 VAPA_2c08370 d6d54584d3556e44e9ae80d962e8571a 373 Pfam PF05935 Arylsulfotransferase (ASST) 239 320 1.2E-7 T 12-10-2018 IPR010262 Arylsulfotransferase, bacteria GO:0004062 VAPA_2c08370 d6d54584d3556e44e9ae80d962e8571a 373 SUPERFAMILY SSF50969 17 305 1.65E-15 T 12-10-2018 IPR011044 Quinoprotein amine dehydrogenase, beta chain-like VAPA_2c08370 d6d54584d3556e44e9ae80d962e8571a 373 Gene3D G3DSA:2.130.10.10 4 347 1.7E-8 T 12-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 VAPA_1c06600 e44c2ea19c4e71d41e59204d041a0c62 402 Gene3D G3DSA:3.30.1540.10 232 324 1.6E-102 T 12-10-2018 VAPA_1c06600 e44c2ea19c4e71d41e59204d041a0c62 402 Pfam PF02515 CoA-transferase family III 6 372 3.7E-95 T 12-10-2018 IPR003673 CoA-transferase family III GO:0003824 VAPA_1c06600 e44c2ea19c4e71d41e59204d041a0c62 402 Gene3D G3DSA:3.40.50.10540 5 390 1.6E-102 T 12-10-2018 IPR023606 CoA-transferase family III domain superfamily VAPA_1c06600 e44c2ea19c4e71d41e59204d041a0c62 402 SUPERFAMILY SSF89796 2 396 1.44E-110 T 12-10-2018 IPR023606 CoA-transferase family III domain superfamily VAPA_2c06240 640a2a7bd7162a7e2b5aebb1d82ef2ba 78 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 29 44 1.0E-6 T 12-10-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 VAPA_2c06240 640a2a7bd7162a7e2b5aebb1d82ef2ba 78 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 44 66 1.0E-6 T 12-10-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 VAPA_2c06240 640a2a7bd7162a7e2b5aebb1d82ef2ba 78 Pfam PF01313 Bacterial export proteins, family 3 6 67 4.2E-13 T 12-10-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 VAPA_2c07820 ea033e78ebc0b81549510d3f7b878dc9 161 Pfam PF07681 DoxX 40 127 7.6E-21 T 12-10-2018 IPR032808 DoxX family VAPA_1c09200 c7ae34d7c2f03ab23917dbdc5851cd4c 276 Gene3D G3DSA:3.40.50.1010 2 141 7.2E-18 T 12-10-2018 VAPA_1c09200 c7ae34d7c2f03ab23917dbdc5851cd4c 276 Pfam PF01936 NYN domain 6 138 4.1E-24 T 12-10-2018 IPR021139 NYN domain, limkain-b1-type VAPA_1c33470 eb9c967aed1090da60170d49ee82ad64 177 Pfam PF11066 Protein of unknown function (DUF2867) 26 161 1.1E-35 T 12-10-2018 IPR021295 Protein of unknown function DUF2867 VAPA_1c08960 2cf5ec5c0415f276017e40c018e51900 194 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 46 175 2.1E-26 T 12-10-2018 IPR007387 TRAP transporter, small membrane protein DctQ VAPA_1c45510 9f6e0e0f1567ab681de6a3953afd03de 154 Pfam PF06127 Protein of unknown function (DUF962) 16 149 2.0E-19 T 12-10-2018 IPR009305 Protein of unknown function DUF962 VAPA_1c15050 0598026a94176f13b7d29c6b1db50506 186 Pfam PF02325 YGGT family 107 174 1.9E-15 T 12-10-2018 IPR003425 CCB3/YggT GO:0016020 VAPA_1c15050 0598026a94176f13b7d29c6b1db50506 186 Pfam PF02325 YGGT family 12 81 4.7E-14 T 12-10-2018 IPR003425 CCB3/YggT GO:0016020 VAPA_1c47440 75cf37c7c359bae24116015157b8bfc8 222 SUPERFAMILY SSF56349 10 197 6.18E-38 T 12-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 VAPA_1c47440 75cf37c7c359bae24116015157b8bfc8 222 Gene3D G3DSA:1.10.443.10 8 196 3.3E-48 T 12-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 VAPA_1c47440 75cf37c7c359bae24116015157b8bfc8 222 Pfam PF00589 Phage integrase family 12 195 6.6E-14 T 12-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 VAPA_1c34620 4d81cae86e5de8c76e93d2de314f41e3 537 Pfam PF01654 Cytochrome bd terminal oxidase subunit I 8 506 5.3E-177 T 12-10-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 VAPA_1c34620 4d81cae86e5de8c76e93d2de314f41e3 537 PIRSF PIRSF006446 1 326 3.1E-112 T 12-10-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 VAPA_1c34620 4d81cae86e5de8c76e93d2de314f41e3 537 PIRSF PIRSF006446 359 528 3.2E-40 T 12-10-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 VAPA_1c44120 9bcc108e0f76c7504718fa5c9075b8be 222 Pfam PF08378 Nuclease-related domain 26 118 1.1E-8 T 12-10-2018 IPR011528 Nuclease-related domain, NERD VAPA_1c04030 31a298700eb3dc1d1409d65d83e3f494 375 Pfam PF10023 Putative aminopeptidase 22 352 2.4E-127 T 12-10-2018 IPR014553 Predicted aminopeptidase VAPA_1c04030 31a298700eb3dc1d1409d65d83e3f494 375 PIRSF PIRSF029285 2 358 7.2E-117 T 12-10-2018 IPR014553 Predicted aminopeptidase VAPA_1c33600 75560ef512fbfcaccb6593707e82f7b0 430 SUPERFAMILY SSF103473 6 408 1.12E-67 T 12-10-2018 IPR036259 MFS transporter superfamily VAPA_1c33600 75560ef512fbfcaccb6593707e82f7b0 430 Gene3D G3DSA:1.20.1250.20 14 411 5.3E-55 T 12-10-2018 VAPA_1c33600 75560ef512fbfcaccb6593707e82f7b0 430 Pfam PF07690 Major Facilitator Superfamily 23 371 5.9E-45 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 VAPA_1c18930 f9d415fd87ab506f23b20fd1c19a5292 238 Pfam PF01618 MotA/TolQ/ExbB proton channel family 94 204 3.8E-36 T 12-10-2018 IPR002898 MotA/TolQ/ExbB proton channel VAPA_2c04060 018ed065040a36f379d2e66dc2a12548 162 SUPERFAMILY SSF48695 13 153 5.86E-6 T 12-10-2018 IPR036280 Multiheme cytochrome superfamily VAPA_2c04060 018ed065040a36f379d2e66dc2a12548 162 Pfam PF09626 Dihaem cytochrome c 43 153 2.1E-36 T 12-10-2018 IPR018588 Dihaem cytochrome c VAPA_1c28790 5788210fdd231469b9e9a302043eb941 213 Pfam PF06532 Protein of unknown function (DUF1109) 10 213 3.1E-58 T 12-10-2018 IPR009495 Anti-sigma-F factor NrsF VAPA_2c03710 2ebe7204c0ceeba3ff7f67d4de35a769 282 Gene3D G3DSA:2.60.120.620 1 257 2.4E-65 T 12-10-2018 VAPA_2c03710 2ebe7204c0ceeba3ff7f67d4de35a769 282 SUPERFAMILY SSF51197 8 241 2.47E-54 T 12-10-2018 VAPA_2c03710 2ebe7204c0ceeba3ff7f67d4de35a769 282 Pfam PF05721 Phytanoyl-CoA dioxygenase (PhyH) 14 197 4.2E-27 T 12-10-2018 IPR008775 Phytanoyl-CoA dioxygenase VAPA_1c11280 5459eb0769e555494cbda0474236fc83 266 Pfam PF01203 Type II secretion system (T2SS), protein N 52 262 1.8E-28 T 12-10-2018 IPR022792 Type II secretion system, protein N VAPA_2c06450 16374b1aacf7ef34c4371b08d4531e09 108 Gene3D G3DSA:3.30.2310.20 1 101 9.3E-13 T 12-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily VAPA_1c50480 83bf0797c7d47bdda357465467975714 333 Pfam PF02653 Branched-chain amino acid transport system / permease component 50 325 1.1E-41 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 VAPA_1c35710 fbcfd70c64465951e15675cdc38a524d 89 Pfam PF13488 Glycine zipper 24 67 8.4E-7 T 12-10-2018 IPR039567 Glycine zipper domain VAPA_1c19800 42176759ade821c198d30b120b942d66 291 Pfam PF07505 Protein of unknown function (DUF5131) 21 290 3.8E-70 T 12-10-2018 IPR011101 Protein of unknown function DUF5131 VAPA_1c01200 b02936ee5fa66f9f8a8ca6477f6ba331 219 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 45 170 2.1E-18 T 12-10-2018 IPR007387 TRAP transporter, small membrane protein DctQ VAPA_1c45190 490a242f01906c3eb9fa6c0442ee9467 98 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 9 20 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site VAPA_1c45190 490a242f01906c3eb9fa6c0442ee9467 98 SUPERFAMILY SSF54862 1 86 6.98E-20 T 12-10-2018 VAPA_1c45190 490a242f01906c3eb9fa6c0442ee9467 98 Gene3D G3DSA:3.30.70.20 2 81 6.2E-33 T 12-10-2018 VAPA_1c45190 490a242f01906c3eb9fa6c0442ee9467 98 Pfam PF00037 4Fe-4S binding domain 6 25 5.3E-6 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain VAPA_1c05130 f7c36ac02c76183aae1d7d058cb13cc9 433 Pfam PF03929 PepSY-associated TM region 8 401 7.6E-56 T 12-10-2018 IPR005625 PepSY-associated TM protein VAPA_1c29600 9ac27e9331336bd84a5d7aad21d495f8 130 Pfam PF06803 Protein of unknown function (DUF1232) 34 69 3.1E-14 T 12-10-2018 IPR010652 Domain of unknown function DUF1232 MetaCyc: PWY-7511 VAPA_1c43710 0bb08a6acddc3228c51549c96e5b8804 174 Pfam PF08750 CNP1-like family 35 167 3.9E-34 T 12-10-2018 IPR014861 Uncharacterised domain CNP1 VAPA_1c15830 990ffba0155a9eb53a906d92d5aa0c3a 502 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 16 202 6.5E-8 T 12-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 VAPA_1c31390 55fedde4baec19750fdb98d03a5215d7 492 SUPERFAMILY SSF51717 127 339 2.88E-22 T 12-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 VAPA_2c03980 7e982646a2be95f75327e7985b5f0ccd 376 Pfam PF12698 ABC-2 family transporter protein 35 365 6.4E-27 T 12-10-2018 VAPA_2c04380 681af2f297a2a84a8aa918ed90cafd07 399 Pfam PF05940 NnrS protein 22 393 7.6E-103 T 12-10-2018 IPR010266 NnrS VAPA_1c46230 419daf024c33057590be8cf40975b4af 326 Pfam PF00482 Type II secretion system (T2SS), protein F 160 285 3.6E-11 T 12-10-2018 IPR018076 Type II secretion system F domain VAPA_1c04290 316d8cf00df979c03bc3f14c36d6e851 300 Pfam PF02653 Branched-chain amino acid transport system / permease component 14 283 8.2E-32 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 VAPA_1c13450 1bd036a7981c90ba3c8c8a7181257d23 617 Pfam PF01435 Peptidase family M48 154 331 1.3E-10 T 12-10-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 VAPA_1c32680 7c0a5b59fd838a45d6335c94883143ef 116 ProDom PD052090 YDCA PRECURSOR SIGNAL ECS2024 31 63 7.0E-9 T 12-10-2018 VAPA_1c12950 d248a33acda84298f2db062425a2cfce 342 Pfam PF02653 Branched-chain amino acid transport system / permease component 13 327 2.1E-20 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 VAPA_1c17580 6fce848f50dd58155059401637034753 135 Pfam PF09842 Predicted membrane protein (DUF2069) 18 120 2.4E-34 T 12-10-2018 IPR018643 Protein of unknown function DUF2069, membrane VAPA_1c54240 8145a596e0dfdbbd7ae1210c4a0478e9 310 Pfam PF00487 Fatty acid desaturase 52 284 7.0E-35 T 12-10-2018 IPR005804 Fatty acid desaturase domain GO:0006629 VAPA_1c13900 f8e64a30052916e4839ee4d06b41df12 59 Pfam PF12244 Protein of unknown function (DUF3606) 6 57 6.3E-24 T 12-10-2018 IPR022037 Protein of unknown function DUF3606 VAPA_1c42710 9dfc7d21d1e0540f3b3020810bb2ad17 284 Pfam PF04250 Protein of unknown function (DUF429) 44 266 4.3E-7 T 12-10-2018 IPR007362 Protein of unknown function DUF429 VAPA_2c04430 ea2a83ffca17190edfa319260f6ccdaa 101 Pfam PF10006 Uncharacterized conserved protein (DUF2249) 10 79 8.9E-28 T 12-10-2018 IPR018720 Domain of unknown function DUF2249 VAPA_1c50760 ebac89c7029fcd48989c88cb246bd390 155 Gene3D G3DSA:1.20.120.1490 39 152 1.0E-11 T 12-10-2018 VAPA_1c50760 ebac89c7029fcd48989c88cb246bd390 155 Pfam PF13801 Heavy-metal resistance 15 138 2.0E-7 T 12-10-2018 IPR025961 Heavy-metal resistance protein VAPA_2c07100 67344b4bb8d57ca165297fedd53692ed 239 Pfam PF11010 Protein of unknown function (DUF2848) 33 230 7.9E-67 T 12-10-2018 IPR021269 Protein of unknown function DUF2848 VAPA_1c34180 475a7f21b6b076b07448c2eec6555605 403 Pfam PF07394 Protein of unknown function (DUF1501) 32 387 1.1E-40 T 12-10-2018 IPR010869 Protein of unknown function DUF1501 VAPA_1c16620 701c3423886cf53f45a70cf42f40f634 305 SUPERFAMILY SSF103481 204 289 1.31E-9 T 12-10-2018 VAPA_2c10270 71f8726afaedaf7a1c6ff0aa07df8ad3 144 Pfam PF13276 HTH-like domain 26 76 2.9E-7 T 12-10-2018 IPR025948 HTH-like domain VAPA_1c50680 0d1bb4949052de0e3cd80dd390050ede 374 Pfam PF03600 Citrate transporter 25 309 3.7E-22 T 12-10-2018 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 Reactome: R-HSA-5662702 VAPA_1c08270 f5a494b9946fd8230517c1f7ee0f91b3 268 Pfam PF01061 ABC-2 type transporter 27 228 4.4E-23 T 12-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 VAPA_2c02060 626e59e7646d36e49070327bdfd1cf7c 102 Pfam PF02796 Helix-turn-helix domain of resolvase 16 41 5.6E-6 T 12-10-2018 IPR006120 Resolvase, HTH domain GO:0000150|GO:0003677|GO:0006310 VAPA_1c16250 482809d595500f3ce423c6b211705e3a 302 Pfam PF00482 Type II secretion system (T2SS), protein F 155 283 1.2E-17 T 12-10-2018 IPR018076 Type II secretion system F domain VAPA_2c07020 e34a8720d7433ad3ee52968505fe321b 307 Pfam PF02653 Branched-chain amino acid transport system / permease component 9 291 3.4E-30 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 VAPA_1c08630 46aa603b172f2455d7f7de0d6756130d 562 Pfam PF02538 Hydantoinase B/oxoprolinase 6 532 2.9E-160 T 12-10-2018 IPR003692 Hydantoinase B/oxoprolinase GO:0003824 Reactome: R-HSA-174403|Reactome: R-HSA-5578998 VAPA_1c37970 7e5467e742bfa742a4d79c38408416ac 155 Pfam PF04214 Protein of unknown function, DUF 61 125 2.1E-30 T 12-10-2018 IPR007332 Protein of unknown function DUF411 VAPA_1c40240 f135ce26055a698848b7023d7f99caaf 459 PIRSF PIRSF005353 20 457 4.6E-176 T 12-10-2018 IPR026033 Purine permease PbuG-like VAPA_1c40240 f135ce26055a698848b7023d7f99caaf 459 Pfam PF00860 Permease family 46 416 3.9E-57 T 12-10-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0016020|GO:0022857|GO:0055085 VAPA_1c45920 00bbffcbb538a5efb010c1d30f4d8a26 125 Pfam PF13451 Probable zinc-ribbon domain 64 110 1.2E-17 T 12-10-2018 IPR025306 Probable zinc-binding domain VAPA_1c32940 f6aae9e65c78e075c982768d143c5e69 309 SUPERFAMILY SSF51445 43 293 6.88E-10 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily VAPA_1c27020 196bf7d513da375a1cfd4a3c1717a503 161 Pfam PF10881 Protein of unknown function (DUF2726) 43 148 1.8E-14 T 12-10-2018 IPR024402 Domain of unknown function DUF2726 VAPA_1c14490 89b1cec793ec81c89fc3290846a72787 181 Pfam PF11937 Protein of unknown function (DUF3455) 40 179 2.7E-32 T 12-10-2018 IPR021851 Protein of unknown function DUF3455 VAPA_1c31900 6e683b84ed0fe103717e7ead6e62c4f8 172 Pfam PF07331 Tripartite tricarboxylate transporter TctB family 26 166 1.5E-17 T 12-10-2018 IPR009936 Protein of unknown function DUF1468 VAPA_1c46170 62faf2a46ca56226ce20e667e29e7c1b 62 Pfam PF04964 Flp/Fap pilin component 8 57 4.6E-15 T 12-10-2018 IPR007047 Flp/Fap pilin component VAPA_1c27760 fb0048e23d08e87a23bde21bb49568c3 69 Gene3D G3DSA:3.10.450.50 3 69 2.4E-11 T 12-10-2018 VAPA_1c45880 21726f7f12f892517aa4456f28b18fd1 158 Pfam PF07681 DoxX 33 112 6.2E-13 T 12-10-2018 IPR032808 DoxX family VAPA_1c21120 af8a83e9fac313f05fa38971c5de7f0b 239 Pfam PF05552 Conserved TM helix 106 146 1.9E-7 T 12-10-2018 IPR008910 Conserved TM helix VAPA_1c21120 af8a83e9fac313f05fa38971c5de7f0b 239 Pfam PF05552 Conserved TM helix 9 56 3.2E-13 T 12-10-2018 IPR008910 Conserved TM helix VAPA_1c04490 efd3188bc223867192b378b2bc82e29c 338 Pfam PF02653 Branched-chain amino acid transport system / permease component 61 325 7.0E-41 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 VAPA_1c46260 234bf6288ccf884372e8343060911ffc 129 Pfam PF12266 Protein of unknown function (DUF3613) 64 116 3.2E-12 T 12-10-2018 IPR022053 Protein of unknown function DUF3613 VAPA_1c35460 367eb1b367bc0be0597af83c33ede198 166 Pfam PF05433 Glycine zipper 2TM domain 75 115 1.2E-5 T 12-10-2018 IPR008816 Glycine zipper 2TM domain GO:0019867 VAPA_2c06440 da12f0bff73d437a82436d6bdd730647 113 Pfam PF13518 Helix-turn-helix domain 7 60 5.2E-6 T 12-10-2018 VAPA_1c20050 1d80517e37e223cd93c62a3d8d097e0c 232 Pfam PF01925 Sulfite exporter TauE/SafE 1 226 3.6E-16 T 12-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 VAPA_2c03650 0f56df70fd980ac0352b500c730ba58c 334 Pfam PF02653 Branched-chain amino acid transport system / permease component 31 300 1.2E-36 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 VAPA_2c04640 c8200cee175edea8f697aba8c0942e3e 796 Pfam PF02687 FtsX-like permease family 304 392 2.6E-7 T 12-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 VAPA_1c40220 5f83ca19edbd95d6d3461f198056da4c 382 Pfam PF02653 Branched-chain amino acid transport system / permease component 61 336 2.0E-38 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 VAPA_1c47500 5dbf3e98ca5fc222ccf38319d03f25ce 90 Pfam PF14026 Protein of unknown function (DUF4242) 4 80 1.6E-27 T 12-10-2018 IPR025336 Protein of unknown function DUF4242 VAPA_2c00610 b5bc43427a79f2b464e4c228419b024b 295 Pfam PF02653 Branched-chain amino acid transport system / permease component 5 278 1.3E-40 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 VAPA_1c32790 827595b5038e02d1aedb06d78d75f538 73 Pfam PF05930 Prophage CP4-57 regulatory protein (AlpA) 27 62 1.5E-7 T 12-10-2018 IPR010260 DNA-binding transcriptional activator AlpA VAPA_1c39250 5adc0c8f344962ee90ccecc580aed4bc 310 Pfam PF04976 DMSO reductase anchor subunit (DmsC) 1 306 7.1E-29 T 12-10-2018 IPR007059 DMSO reductase anchor subunit (DmsC) GO:0016021|GO:0019645 VAPA_1c51340 74a3a7ee96de63a356311b898f8fe2e5 652 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 42 312 3.2E-35 T 12-10-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit VAPA_1c51340 74a3a7ee96de63a356311b898f8fe2e5 652 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 441 642 7.3E-40 T 12-10-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit VAPA_1c04690 8e3d2adcdcd0e49a096a6205ac310618 109 Pfam PF12769 4TM region of pyridine nucleotide transhydrogenase, mitoch 11 94 3.7E-35 T 12-10-2018 IPR024605 NAD(P) transhydrogenase, alpha subunit, C-terminal KEGG: 00760+1.6.1.2|Reactome: R-HSA-71403 VAPA_2c07850 44dbebd8605f7ca27a2e42ae45a7474d 95 Pfam PF10048 Predicted integral membrane protein (DUF2282) 35 89 2.6E-26 T 12-10-2018 IPR018740 Protein of unknown function DUF2282, integral membrane VAPA_1c52270 a8541d66e953d0bf2f9bd98847e24d87 107 Pfam PF08895 Domain of unknown function (DUF1840) 1 105 4.2E-29 T 12-10-2018 IPR014991 Protein of unknown function DUF1840 VAPA_1c00930 8d4d1c9249df70305c274ff0deea44df 157 Pfam PF16155 Domain of unknown function (DUF4863) 10 155 1.7E-55 T 12-10-2018 IPR032345 Protein of unknown function DUF4863 VAPA_1c09300 3bbd7f88e07ba3715ba2f6cddefb184e 68 Pfam PF07869 Protein of unknown function (DUF1656) 4 58 1.9E-21 T 12-10-2018 IPR012451 Protein of unknown function DUF1656 VAPA_1c17960 a2c09855544843e4802941bb58163c37 469 Pfam PF04293 SpoVR like protein 1 409 2.6E-165 T 12-10-2018 IPR007390 Sporulation stage V, protein R VAPA_2c08320 97d6a506936920836c1c8c3f2ee6dfa8 100 SUPERFAMILY SSF89796 15 87 1.74E-6 T 12-10-2018 IPR023606 CoA-transferase family III domain superfamily VAPA_1c33300 d54e3dd0660bb8ceae12fd8db3c06dda 151 Pfam PF07681 DoxX 22 107 1.0E-12 T 12-10-2018 IPR032808 DoxX family VAPA_1c44640 c1ab6984c44d90eff021cb7a097bd448 1189 Pfam PF13289 SIR2-like domain 125 260 9.9E-20 T 12-10-2018 IPR039444 SIR2-like domain VAPA_2c02880 bbeae1edb42deac187c9c93743c0795f 251 Pfam PF01925 Sulfite exporter TauE/SafE 13 240 8.7E-29 T 12-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 VAPA_1c15620 f6373f713bde4ce05fac13062a43ba1f 336 Pfam PF01384 Phosphate transporter family 25 325 1.1E-87 T 12-10-2018 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: R-HSA-427652 VAPA_1c37120 b1f976c50ac4f70bda1aaa1e522fe33c 246 Pfam PF03591 AzlC protein 31 175 9.0E-29 T 12-10-2018 IPR011606 Branched-chain amino acid transport, permease