locus-tag	class	description
Varpa_0001	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
Varpa_0002	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
Varpa_0003	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
Varpa_0008	ENOG4107RN3	metallophosphoesterase
Varpa_0011	ENOG4107UXM	Membrane
Varpa_0012	ENOG4105DZQ	phospholipase D Transphosphatidylase
Varpa_0013	ENOG4105X23	Endonuclease Exonuclease phosphatase
Varpa_0017	ENOG4105EUB	pirin domain protein
Varpa_0019	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
Varpa_0020	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
Varpa_0024	ENOG4105CT7	inner membrane cred family protein
Varpa_0026	ENOG4108JQC	penicillin-binding protein 1A
Varpa_0028	ENOG4105EB3	Histidine kinase
Varpa_0029	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
Varpa_0032	ENOG410681U	heavy metal transport detoxification protein
Varpa_0033	ENOG4105C59	p-type ATPase
Varpa_0034	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
Varpa_0037	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
Varpa_0039	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
Varpa_0040	ENOG4105ECM	Sensor protein basS pmrB
Varpa_0041	ENOG4108YZK	glyoxalase bleomycin resistance protein dioxygenase
Varpa_0044	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
Varpa_0046	ENOG4105E39	Enoyl-CoA hydratase
Varpa_0047	ENOG4108K3A	Glutathione S-transferase
Varpa_0050	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
Varpa_0051	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
Varpa_0052	ENOG4108NIW	Leucine export protein LeuE
Varpa_0053	ENOG4107QJE	Chromosome Partitioning Protein
Varpa_0055	ENOG4105FA0	parb-like partition protein
Varpa_0057	ENOG4105CQB	FAD linked oxidase domain protein
Varpa_0059	ENOG4108WBT	adenosyltransferase
Varpa_0066	ENOG4107R11	Transcriptional regulator
Varpa_0073	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
Varpa_0074	ENOG4107QMS	site-determining protein
Varpa_0075	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
Varpa_0076	ENOG4105C2W	permease
Varpa_0077	ENOG4105KA0	thioesterase Superfamily protein
Varpa_0079	ENOG4105BZ1	(ABC) transporter
Varpa_0084	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
Varpa_0085	ENOG4105E39	Enoyl-CoA hydratase
Varpa_0089	ENOG4105F35	Catalyzes the NAD( )-dependent oxidation of L-carnitine to 3-dehydrocarnitine (By similarity)
Varpa_0091	ENOG4105DE9	3-keto-5-aminohexanoate cleavage enzyme
Varpa_0093	ENOG4105VSH	4-oxalocrotonate tautomerase
Varpa_0094	ENOG4105CHR	reductase
Varpa_0095	ENOG4105EXG	Transcriptional regulator
Varpa_0096	ENOG4108IV0	ABC, transporter
Varpa_0097	ENOG4105C0Z	ABC transporter
Varpa_0099	ENOG4105C32	Amino acid ABC transporter (Permease)
Varpa_0101	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
Varpa_0105	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
Varpa_0106	ENOG4105CNM	Receptor
Varpa_0114	ENOG4108JU3	Alkyl hydroperoxide reductase
Varpa_0116	ENOG4107XCH	Cyclase family
Varpa_0117	ENOG4105Y36	Binding-protein-dependent transport systems, inner membrane component
Varpa_0118	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
Varpa_0122	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
Varpa_0124	ENOG4108T5G	Adenylate
Varpa_0128	ENOG4108W3Q	Transcriptional regulator
Varpa_0129	ENOG4105ETT	transcriptional Regulator, LysR family
Varpa_0130	ENOG4105C1G	acyl-Coa dehydrogenase
Varpa_0131	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
Varpa_0135	ENOG4105RRV	Inherit from COG: copper resistance
Varpa_0137	ENOG4108RG0	uracil-dna glycosylase
Varpa_0140	ENOG4105DUM	transcriptional regulator, lysR family
Varpa_0141	ENOG4105DCY	Is an aliphatic amidase with a restricted substrate specificity, as it only hydrolyzes formamide (By similarity)
Varpa_0145	ENOG4105CSV	Glutaminase
Varpa_0152	ENOG4105DND	Transcriptional regulator
Varpa_0153	ENOG4105EUZ	Beta-lactamase domain protein
Varpa_0155	ENOG4107RZC	phospholipase d
Varpa_0158	ENOG4108IV0	ABC, transporter
Varpa_0159	ENOG4105C0Z	ABC transporter
Varpa_0162	ENOG4105CAD	extracellular ligand-binding receptor
Varpa_0163	ENOG4107Z7P	Ferredoxin
Varpa_0172	ENOG4105C0M	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle (By similarity)
Varpa_0174	ENOG4105C7B	Threonine dehydratase
Varpa_0175	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
Varpa_0177	ENOG4105DU0	nucleoside hydrolase
Varpa_0178	ENOG4105C9U	ATP-dependent DNA helicase RecQ
Varpa_0180	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
Varpa_0182	ENOG4105CZE	histidine utilization repressor
Varpa_0183	ENOG4105C84	Histidine ammonia-lyase
Varpa_0184	ENOG4105CGP	Urocanate hydratase
Varpa_0186	ENOG4105EAB	amino acid AbC transporter
Varpa_0187	ENOG4105E5Q	amino acid AbC transporter
Varpa_0189	ENOG41090B9	response to stress
Varpa_0190	ENOG4105CI2	imidazolone-5-propionate hydrolase
Varpa_0191	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
Varpa_0194	ENOG4105C3R	Methionine synthase
Varpa_0196	ENOG4105F52	Transcriptional regulator
Varpa_0199	ENOG4107IFA	Lipase (EC 3.1.1.3)
Varpa_0200	ENOG4105C3R	Methionine synthase
Varpa_0201	ENOG41063ZV	
Varpa_0202	ENOG41089I4	Inherit from COG: Glycosyl transferase, family 2
Varpa_0205	ENOG4108W9H	Tetr family transcriptional regulator
Varpa_0206	ENOG4105DP0	ferredoxin-NADP reductase
Varpa_0211	ENOG41083Z3	extracellular ligand-binding receptor
Varpa_0213	ENOG4105C0Z	ABC transporter
Varpa_0214	ENOG4108IV0	ABC, transporter
Varpa_0215	ENOG4108RWI	nicotinamidase
Varpa_0217	ENOG4108XHQ	(2Fe-2S)-binding domain protein
Varpa_0218	ENOG4105CE2	Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding
Varpa_0220	ENOG4105C0P	Mg chelatase subunit ChlI
Varpa_0222	ENOG4108YZA	Nitrogen regulatory protein pii
Varpa_0223	ENOG4105BZU	Histidine kinase
Varpa_0226	ENOG4105CQB	FAD linked oxidase domain protein
Varpa_0227	ENOG4105EU8	FAD linked oxidase domain protein
Varpa_0228	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
Varpa_0230	ENOG4108V06	Glutathione peroxidase
Varpa_0232	ENOG4108J8Q	Catalyzes the facilitated diffusion of 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) into the cell (By similarity)
Varpa_0233	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
Varpa_0235	ENOG4105EXG	Transcriptional regulator
Varpa_0237	ENOG41084M5	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
Varpa_0238	ENOG4105MP9	class II Aldolase
Varpa_0239	ENOG4105JN3	extra-cytoplasmic solute receptor family protein
Varpa_0247	ENOG4105C26	Dehydrogenase
Varpa_0251	ENOG4108V8F	Transcriptional regulator, MarR family
Varpa_0252	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
Varpa_0256	ENOG4105CSH	Transporter
Varpa_0257	ENOG4105CH2	amidohydrolase
Varpa_0258	ENOG4105DH7	May be involved in recombination (By similarity)
Varpa_0259	ENOG4105CM2	brancheD-chain amino acid aminotransferase
Varpa_0264	ENOG4105E0F	Histidine kinase
Varpa_0265	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
Varpa_0266	ENOG4107YHX	fad dependent oxidoreductase
Varpa_0272	ENOG4105GVF	(ABC) transporter
Varpa_0273	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
Varpa_0279	ENOG4105DCY	Is an aliphatic amidase with a restricted substrate specificity, as it only hydrolyzes formamide (By similarity)
Varpa_0280	ENOG4106XMA	In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity)
Varpa_0281	ENOG4108JQ9	ABC transporter
Varpa_0285	ENOG41061H0	Monooxygenase
Varpa_0286	ENOG4105F04	LysR family Transcriptional regulator
Varpa_0287	ENOG4105CGK	Exodeoxyribonuclease III
Varpa_0288	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
Varpa_0290	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
Varpa_0291	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
Varpa_0292	ENOG41080G2	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
Varpa_0293	ENOG4105DFF	Rod shape-determining protein mreb
Varpa_0296	ENOG4105CJN	penicillin-binding protein
Varpa_0297	ENOG4105ERH	Fumarylacetoacetate hydrolase
Varpa_0299	ENOG4105F1J	Homogentisate 1,2-dioxygenase
Varpa_0301	ENOG4105E2Q	3-(3-hydroxy-phenyl)propionate hydroxylase
Varpa_0304	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
Varpa_0309	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
Varpa_0311	ENOG4105CN8	Transcriptional regulator
Varpa_0312	ENOG4105C26	Dehydrogenase
Varpa_0314	ENOG4105CZ6	Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine (By similarity)
Varpa_0319	ENOG4105D38	putrescine abc transporter
Varpa_0320	ENOG4105F38	ABC transporter, permease
Varpa_0321	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
Varpa_0326	ENOG4105CHM	Aminotransferase
Varpa_0327	ENOG4105C7K	acetolactate synthase
Varpa_0329	ENOG4105CH2	amidohydrolase
Varpa_0330	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
Varpa_0331	ENOG4105CWC	Acetylornithine deacetylase
Varpa_0332	ENOG4106BRA	Membrane
Varpa_0334	ENOG4105BZU	Histidine kinase
Varpa_0335	ENOG4107QX3	carboxylase
Varpa_0338	ENOG4105C1G	acyl-Coa dehydrogenase
Varpa_0339	ENOG4105C1G	acyl-Coa dehydrogenase
Varpa_0341	ENOG4105C1J	atp-dependent rna helicase
Varpa_0342	ENOG4108ZJT	translation initiation factor, Sui1
Varpa_0344	ENOG4105VFU	Rna-binding protein
Varpa_0347	ENOG4105BZU	Histidine kinase
Varpa_0350	ENOG4108J2R	molybdopterin oxidoreductase
Varpa_0353	ENOG4105CHR	reductase
Varpa_0354	ENOG4105CMG	Carbohydrate kinase
Varpa_0355	ENOG4105CPQ	Dehydrogenase
Varpa_0356	ENOG4105CNN	ABC, transporter
Varpa_0358	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
Varpa_0359	ENOG4107S4Z	Activates expression of the rhaBAD and rhaT operons (By similarity)
Varpa_0360	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
Varpa_0370	ENOG4105MSY	salicylate hydroxylase
Varpa_0373	ENOG4105C3M	thioredoxin reductase
Varpa_0375	ENOG4105C29	acyl-CoA thioesterase
Varpa_0376	ENOG4107MKT	Stringent starvation protein a
Varpa_0377	ENOG4105EQR	Transposase IS116 IS110 IS902
Varpa_0378	ENOG4105CHR	reductase
Varpa_0379	ENOG4105CHH	sulfate transporter
Varpa_0381	ENOG4108IV0	ABC, transporter
Varpa_0382	ENOG4105C0Z	ABC transporter
Varpa_0383	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
Varpa_0384	ENOG4105C32	Amino acid ABC transporter (Permease)
Varpa_0386	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
Varpa_0388	ENOG41061GT	Aldolase
Varpa_0389	ENOG4108FN7	Aldo keto reductase
Varpa_0390	ENOG4105CNN	ABC, transporter
Varpa_0393	ENOG4105CMG	Carbohydrate kinase
Varpa_0395	ENOG4105FDP	GntR family transcriptional regulator
Varpa_0398	ENOG4108UUM	single-stranded DNA-binding protein
Varpa_0401	ENOG4105CDY	transcriptional regulatory protein
Varpa_0402	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
Varpa_0403	ENOG4108JJB	ABC transporter
Varpa_0405	ENOG4107ZYJ	bioY protein
Varpa_0412	ENOG4105DEN	Luciferase family
Varpa_0413	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
Varpa_0416	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
Varpa_0417	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
Varpa_0418	ENOG4105W8H	transhydrogenase (subunit alpha
Varpa_0419	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
Varpa_0420	ENOG4105CEY	Amp-dependent synthetase and ligase
Varpa_0421	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
Varpa_0422	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
Varpa_0423	ENOG4105C3U	ABC transporter
Varpa_0424	ENOG4108JQ7	(ABC) transporter
Varpa_0425	ENOG4105DEF	Extracellular solute-binding protein, family 5
Varpa_0426	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
Varpa_0428	ENOG4107QUT	magnesium and cobalt transport protein CorA
Varpa_0430	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
Varpa_0431	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
Varpa_0432	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
Varpa_0433	ENOG41090R7	Ferric uptake
Varpa_0434	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
Varpa_0435	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
Varpa_0437	ENOG4105SG9	biopolymer transport protein, ExbD
Varpa_0438	ENOG4107QQN	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
Varpa_0439	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
Varpa_0440	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
Varpa_0441	ENOG4108IUM	Glycogen debranching enzyme
Varpa_0444	ENOG4105CG3	alpha amylase, catalytic region
Varpa_0445	ENOG4105E1J	oxidoreductase
Varpa_0446	ENOG4105C8T	Leucyl-tRNA synthetase
Varpa_0449	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
Varpa_0451	ENOG4105DFH	Transport of potassium into the cell (By similarity)
Varpa_0454	ENOG4105D7Z	glutathione synthase
Varpa_0457	ENOG4105E7A	Glutamine amidotransferase
Varpa_0459	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
Varpa_0462	ENOG4107R15	K00850 6-phosphofructokinase 1 EC 2.7.1.11
Varpa_0463	ENOG4108UKI	Enoyl-CoA hydratase
Varpa_0465	ENOG4105ETT	transcriptional Regulator, LysR family
Varpa_0469	ENOG4105DFS	Conserved Protein
Varpa_0471	ENOG4107QP3	malate synthase g
Varpa_0472	ENOG4105CIH	Imidazole acetol-phosphate transaminase
Varpa_0474	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
Varpa_0475	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
Varpa_0479	ENOG4105C75	arginyL-tRNA synthetase
Varpa_0481	ENOG4108Z33	Thiol disulfide Interchange Protein
Varpa_0482	ENOG4105WI0	lipopolysaccharide transport periplasmic protein lptA
Varpa_0483	ENOG4108IUZ	ABC transporter
Varpa_0484	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
Varpa_0485	ENOG4107RZC	phospholipase d
Varpa_0489	ENOG4105DS1	cytochrome b561
Varpa_0491	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
Varpa_0501	ENOG4105E4G	Type IV pilus
Varpa_0509	ENOG4105CBC	glutamate synthase
Varpa_0510	ENOG4106RHG	Yeca family
Varpa_0521	ENOG4105DUM	transcriptional regulator, lysR family
Varpa_0523	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
Varpa_0524	ENOG4106KXD	ATP-dependent carboxylate-amine ligase (By similarity)
Varpa_0527	ENOG4105NWN	ApaG protein
Varpa_0528	ENOG4105DJV	ribulose-phosphate 3-epimerase
Varpa_0531	ENOG4105FDF	Could be involved in DNA repair (By similarity)
Varpa_0532	ENOG4105DQE	DNA ligase
Varpa_0537	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
Varpa_0538	ENOG4105CS6	Rhs element vgr protein
Varpa_0541	ENOG4105IB0	filamentous hemagglutinin family outer membrane protein
Varpa_0544	ENOG4108RWI	nicotinamidase
Varpa_0545	ENOG4105ECQ	AraC Family Transcriptional Regulator
Varpa_0546	ENOG4105ES5	Histidine kinase
Varpa_0548	ENOG4105BZU	Histidine kinase
Varpa_0549	ENOG4105EHI	Phosphonate ABC transporter, periplasmic
Varpa_0550	ENOG4105EHI	Phosphonate ABC transporter, periplasmic
Varpa_0552	ENOG4106VK6	Flagellar motor protein
Varpa_0556	ENOG4105D9P	serine threonine protein kinase
Varpa_0567	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
Varpa_0568	ENOG4105CS6	Rhs element vgr protein
Varpa_0573	ENOG4105CS6	Rhs element vgr protein
Varpa_0584	ENOG4108WC9	type VI secretion system effector, hcp1 family
Varpa_0592	ENOG4105H3G	oxidoreductase
Varpa_0599	ENOG4107SQD	Transcriptional regulator, GntR family
Varpa_0603	ENOG4105BZU	Histidine kinase
Varpa_0604	ENOG4108RYR	transcriptional regulator AsnC family
Varpa_0606	ENOG4105JPG	D-isomer specific 2-hydroxyacid dehydrogenase
Varpa_0609	ENOG4105CJP	fad dependent oxidoreductase
Varpa_0610	ENOG4108J59	Extracellular solute-binding protein, family 5
Varpa_0612	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
Varpa_0614	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
Varpa_0615	ENOG4105C26	Dehydrogenase
Varpa_0618	ENOG4108DN8	FAD dependent oxidoreductase
Varpa_0619	ENOG4108Z7F	N-acetyltransferase
Varpa_0620	ENOG4105CJP	fad dependent oxidoreductase
Varpa_0621	ENOG4105E0K	tonB-dependent siderophore receptor
Varpa_0624	ENOG4108JPW	Aminotransferase
Varpa_0625	ENOG4108RYR	transcriptional regulator AsnC family
Varpa_0626	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
Varpa_0630	ENOG4105DDQ	anthranilate synthase
Varpa_0633	ENOG4107QYG	anthranilate phosphoribosyltransferase
Varpa_0634	ENOG4105DK0	Indole-3-glycerol phosphate synthase
Varpa_0635	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
Varpa_0636	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
Varpa_0639	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
Varpa_0640	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
Varpa_0641	ENOG4108VZM	50s ribosomal protein L10
Varpa_0642	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
Varpa_0643	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
Varpa_0644	ENOG4107QR0	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
Varpa_0646	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
Varpa_0648	ENOG4105ES5	Histidine kinase
Varpa_0653	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
Varpa_0672	ENOG4105DFP	Integrase
Varpa_0679	ENOG4105BZU	Histidine kinase
Varpa_0686	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
Varpa_0690	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
Varpa_0698	ENOG4108KN7	Removes 5-oxoproline from various penultimate amino acid residues except L-proline (By similarity)
Varpa_0700	ENOG4105P4J	Allophanate hydrolase, subunit 1
Varpa_0701	ENOG4108JIK	carboxylase
Varpa_0702	ENOG4105CPT	Alpha beta hydrolase
Varpa_0705	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
Varpa_0707	ENOG4105DZG	Dehydrogenase
Varpa_0709	ENOG4105JIE	May be involved in the transport of PQQ or its precursor to the periplasm (By similarity)
Varpa_0710	ENOG41086XE	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ (By similarity)
Varpa_0711	ENOG4105WF7	pyrroloquinoline quinone biosynthesis protein d
Varpa_0712	ENOG4105EZY	Pyrroloquinoline quinone biosynthesis protein E
Varpa_0715	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
Varpa_0716	ENOG4105XDZ	Tripartite ATP-independent periplasmic transporter
Varpa_0717	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
Varpa_0718	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
Varpa_0719	ENOG41069M3	Transcriptional regulator
Varpa_0720	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
Varpa_0722	ENOG4105T16	Transcriptional regulator (AraC family)
Varpa_0726	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
Varpa_0727	ENOG4108ZHJ	Organic hydroperoxide resistance protein
Varpa_0728	ENOG4105E0F	Histidine kinase
Varpa_0730	ENOG4108ESY	Metal dependent phosphohydrolase
Varpa_0733	ENOG4105CHU	acetyl-coa acetyltransferase
Varpa_0734	ENOG4105CHR	reductase
Varpa_0735	ENOG4105CQZ	Histidine kinase
Varpa_0736	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
Varpa_0737	ENOG4107RW9	nh(3)-dependent nad( ) synthetase
Varpa_0738	ENOG4105HDD	phospholipase
Varpa_0740	ENOG4105C4R	Atp-dependent dna helicase
Varpa_0741	ENOG4105RK9	auxin efflux carrier
Varpa_0745	ENOG4105C25	Primosomal protein n'
Varpa_0746	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
Varpa_0748	ENOG4108IFH	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
Varpa_0749	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
Varpa_0752	ENOG4108YYQ	gCN5-related N-acetyltransferase
Varpa_0755	ENOG4105CBN	LysR family transcriptional regulator
Varpa_0756	ENOG4105EWI	Short-chain dehydrogenase reductase Sdr
Varpa_0759	ENOG410829K	Lysine exporter protein (Lyse ygga)
Varpa_0761	ENOG4105JAB	phenazine biosynthesis protein, phzf family
Varpa_0762	ENOG4108TGY	Glutathione S-transferase
Varpa_0763	ENOG4108NIW	Leucine export protein LeuE
Varpa_0764	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
Varpa_0765	ENOG4105T38	integral membrane protein
Varpa_0767	ENOG4105CHM	Aminotransferase
Varpa_0770	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
Varpa_0772	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
Varpa_0774	ENOG4108IAJ	Nad-dependent epimerase dehydratase
Varpa_0775	ENOG4107V9E	glucose-1-phosphate thymidylyltransferase
Varpa_0777	ENOG4107QPH	glycogen) synthase
Varpa_0778	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
Varpa_0779	ENOG4105CMR	udp-glucose 4-epimerase
Varpa_0781	ENOG4107RGC	Glycosyl transferase, family 2
Varpa_0785	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
Varpa_0786	ENOG4107S6X	Glycosyl transferase, family 2
Varpa_0787	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
Varpa_0795	ENOG4105EXC	Acyl-transferase
Varpa_0798	ENOG4105CAS	nag kinase
Varpa_0799	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
Varpa_0800	ENOG4105DG4	malate L-lactate dehydrogenase
Varpa_0802	ENOG4105CNN	ABC, transporter
Varpa_0805	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
Varpa_0806	ENOG4105CTX	dehydratase
Varpa_0807	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
Varpa_0809	ENOG4108ERU	trap dicarboxylate transporter subunit DctP
Varpa_0810	ENOG4107YCY	Transcriptional regulator
Varpa_0811	ENOG4105I7Z	Short-chain dehydrogenase reductase Sdr
Varpa_0812	ENOG4106517	Short-chain dehydrogenase reductase Sdr
Varpa_0815	ENOG4105CZE	histidine utilization repressor
Varpa_0816	ENOG41083Z3	extracellular ligand-binding receptor
Varpa_0817	ENOG4105C32	Amino acid ABC transporter (Permease)
Varpa_0818	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
Varpa_0819	ENOG4105C0Z	ABC transporter
Varpa_0820	ENOG4108IV0	ABC, transporter
Varpa_0822	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
Varpa_0823	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
Varpa_0827	ENOG4105CX0	fumarate reductase succinate dehydrogenase flavoprotein domain protein
Varpa_0829	ENOG4107R11	Transcriptional regulator
Varpa_0830	ENOG4105EMU	Dehydrogenase
Varpa_0835	ENOG4105CSU	acyl-Coa dehydrogenase
Varpa_0838	ENOG4105WDY	DNA (cytosine-5-)-methyltransferase
Varpa_0839	ENOG4105CHU	acetyl-coa acetyltransferase
Varpa_0842	ENOG4105CHR	reductase
Varpa_0844	ENOG4105E39	Enoyl-CoA hydratase
Varpa_0845	ENOG4105CAD	extracellular ligand-binding receptor
Varpa_0846	ENOG4105NAU	thioesterase Superfamily protein
Varpa_0847	ENOG4108JJ7	ABC transporter
Varpa_0848	ENOG4105C5I	Dehydrogenase
Varpa_0849	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
Varpa_0850	ENOG4107YNJ	LysR family Transcriptional regulator
Varpa_0851	ENOG4108IJ0	Aspartate ammonia-lyase
Varpa_0852	ENOG4107RP9	extracellular solute-binding protein, family 3
Varpa_0853	ENOG4105EAD	ABC transporter
Varpa_0854	ENOG4105DRP	amino acid AbC transporter
Varpa_0855	ENOG4105CDA	abc transporter atp-binding protein
Varpa_0857	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
Varpa_0858	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
Varpa_0859	ENOG410835K	Tripartite ATP-Independent Periplasmic transporter DctQ
Varpa_0860	ENOG410642W	LysR family Transcriptional regulator
Varpa_0865	ENOG4105ENX	hydrolase
Varpa_0867	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
Varpa_0869	ENOG4105EA8	2-Nitropropane dioxygenase
Varpa_0870	ENOG4105C10	Electron transfer flavoprotein
Varpa_0871	ENOG4105BZJ	Electron transfer flavoprotein
Varpa_0873	ENOG4105CEY	Amp-dependent synthetase and ligase
Varpa_0875	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
Varpa_0877	ENOG4105C1G	acyl-Coa dehydrogenase
Varpa_0878	ENOG4105CC9	acyl-Coa dehydrogenase
Varpa_0879	ENOG4105CHU	acetyl-coa acetyltransferase
Varpa_0881	ENOG4105CBN	LysR family transcriptional regulator
Varpa_0883	ENOG4108V1U	phospholipid-binding protein
Varpa_0886	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
Varpa_0889	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
Varpa_0892	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
Varpa_0893	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
Varpa_0894	ENOG4105DEF	Extracellular solute-binding protein, family 5
Varpa_0896	ENOG4105EKE	dihydroorotase
Varpa_0900	ENOG4105D0M	Protease HtpX homolog
Varpa_0902	ENOG4105EW6	flavin reductase domain protein, FMN-binding
Varpa_0904	ENOG4105DZ0	fad dependent oxidoreductase
Varpa_0906	ENOG4108NKP	c4-dicarboxylate transporter malic acid transport protein
Varpa_0909	ENOG4107Z11	Efflux pump whose substrates are p-hydroxybenzoic acid (pHBA), 6-hydroxy-2-naphthoic and 2-hydroxycinnamate. Could function as a metabolic relief valve, allowing to eliminate certain compounds when they accumulate to high levels in the cell (By similarity)
Varpa_0910	ENOG4105ZQC	membrane protein AaeX
Varpa_0911	ENOG4105Y49	secretion protein, HlyD family
Varpa_0913	ENOG4105C2C	drug resistance transporter, Bcr CflA
Varpa_0915	ENOG4105FE9	pseudouridine synthase
Varpa_0928	ENOG4105CC0	LysR family Transcriptional regulator
Varpa_0930	ENOG4105NN7	muconolactone delta-isomerase
Varpa_0931	ENOG4108UAU	isochorismatase
Varpa_0935	ENOG4105E7U	AraC family transcriptional regulator
Varpa_0939	ENOG4105E7U	AraC family transcriptional regulator
Varpa_0941	ENOG4105CV8	reductase
Varpa_0942	ENOG4105F27	Major Facilitator
Varpa_0949	ENOG4105EMN	RNA polymerase sigma factor
Varpa_0953	ENOG4105EQ1	Transcriptional regulator
Varpa_0954	ENOG4105CHJ	isochorismatase hydrolase
Varpa_0956	ENOG4105CPN	adenine deaminase
Varpa_0957	ENOG4108SB3	DoxX Family
Varpa_0959	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
Varpa_0962	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
Varpa_0963	ENOG4105DR4	Methyltransferase
Varpa_0964	ENOG4105CKI	cobalamin synthesis protein
Varpa_0966	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
Varpa_0968	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
Varpa_0969	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
Varpa_0970	ENOG4108V6E	Cell division protein mraZ
Varpa_0971	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
Varpa_0974	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
Varpa_0975	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
Varpa_0976	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
Varpa_0977	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
Varpa_0978	ENOG4105CNI	cell division protein FtsW
Varpa_0979	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
Varpa_0980	ENOG4105DFU	Cell wall formation (By similarity)
Varpa_0981	ENOG4105CPF	Cell wall formation (By similarity)
Varpa_0982	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
Varpa_0983	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
Varpa_0984	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
Varpa_0985	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
Varpa_0987	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
Varpa_0988	ENOG4105KNE	Phosphatidate cytidylyltransferase
Varpa_0992	ENOG4105E2X	shikimate dehydrogenase
Varpa_0994	ENOG4108IEC	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction (By similarity)
Varpa_0995	ENOG4105IPS	esterase
Varpa_0996	ENOG4105WH1	Two component transcriptional regulator luxr family
Varpa_0997	ENOG4105ENE	Histidine kinase
Varpa_0998	ENOG4105CNI	cell division protein FtsW
Varpa_0999	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
Varpa_1001	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
Varpa_1003	ENOG4105DFU	Cell wall formation (By similarity)
Varpa_1005	ENOG4107QXG	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
Varpa_1006	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
Varpa_1007	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
Varpa_1008	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
Varpa_1012	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
Varpa_1013	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
Varpa_1015	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
Varpa_1016	ENOG4107TUY	Histidine kinase
Varpa_1018	ENOG4105CRE	cytochrome C
Varpa_1019	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
Varpa_1020	ENOG4105C3A	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) (By similarity)
Varpa_1021	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
Varpa_1023	ENOG4107WP9	Histidine kinase
Varpa_1024	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
Varpa_1027	ENOG4105BZS	acriflavin resistance protein
Varpa_1034	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
Varpa_1039	ENOG4105E2B	Taurine dioxygenase
Varpa_1042	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
Varpa_1043	ENOG4105M0Y	
Varpa_1049	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
Varpa_1051	ENOG4105C1K	alpha-alpha-trehalose-phosphate synthase
Varpa_1052	ENOG4105BZP	glycoside hydrolase 15-related
Varpa_1053	ENOG4108K4C	ec 3.1.3.12
Varpa_1055	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
Varpa_1057	ENOG4108RXX	maleylacetoacetate isomerase
Varpa_1058	ENOG4108302	MgtC SapB transporter
Varpa_1059	ENOG4107SC1	transglycosylase
Varpa_1060	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
Varpa_1061	ENOG4105ETT	transcriptional Regulator, LysR family
Varpa_1064	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
Varpa_1066	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
Varpa_1067	ENOG4105EW9	transcriptional regulator AsnC family
Varpa_1068	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
Varpa_1071	ENOG4108EG7	Binding-protein-dependent transport systems, inner membrane component
Varpa_1074	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
Varpa_1075	ENOG4105EW9	transcriptional regulator AsnC family
Varpa_1077	ENOG4106PGW	Short-chain dehydrogenase reductase Sdr
Varpa_1079	ENOG4105C2J	ABC transporter
Varpa_1080	ENOG4105D4B	ABC, transporter
Varpa_1081	ENOG4105CNN	ABC, transporter
Varpa_1082	ENOG4108RVA	ribokinase
Varpa_1083	ENOG4105NWF	RbsD or FucU transport
Varpa_1084	ENOG4105C26	Dehydrogenase
Varpa_1087	ENOG4108XM1	transcriptional regulator AsnC family
Varpa_1093	ENOG4105D3Q	Sugar transferase
Varpa_1101	ENOG4105C26	Dehydrogenase
Varpa_1105	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
Varpa_1108	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
Varpa_1109	ENOG4105CYF	SMP-30 gluconolaconase LRE domain protein
Varpa_1110	ENOG4105FGE	Short-chain dehydrogenase reductase Sdr
Varpa_1112	ENOG4105C26	Dehydrogenase
Varpa_1113	ENOG4107R5U	Periplasmic binding protein LacI transcriptional regulator
Varpa_1114	ENOG4105DFW	ABC transporter
Varpa_1116	ENOG4108HWW	ABC transporter
Varpa_1117	ENOG4105C2J	ABC transporter
Varpa_1118	ENOG4107R9N	ABC transporter
Varpa_1119	ENOG41062B0	ABC transporter, permease
Varpa_1122	ENOG4105CBN	LysR family transcriptional regulator
Varpa_1123	ENOG4105CHR	reductase
Varpa_1127	ENOG4107RRY	Cyanophycin synthetase
Varpa_1128	ENOG4107RRY	Cyanophycin synthetase
Varpa_1129	ENOG4105BZ1	(ABC) transporter
Varpa_1131	ENOG4105EXC	Acyl-transferase
Varpa_1133	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
Varpa_1134	ENOG4105CQ0	ABC transporter
Varpa_1136	ENOG4105C4Y	ABC transporter
Varpa_1138	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
Varpa_1139	ENOG4105E0C	molybdate abc transporter
Varpa_1140	ENOG4105DCM	major facilitator superfamily
Varpa_1141	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
Varpa_1145	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
Varpa_1146	ENOG4105HSS	phospholipase C
Varpa_1148	ENOG4105HSS	phospholipase C
Varpa_1149	ENOG4105HSS	phospholipase C
Varpa_1154	ENOG4105D7Q	type ii secretion system
Varpa_1155	ENOG4107QHF	type ii secretion system protein e
Varpa_1156	ENOG4105GVR	general secretion pathway protein D
Varpa_1164	ENOG4108VAU	general secretion pathway protein G
Varpa_1166	ENOG4105C7B	Threonine dehydratase
Varpa_1168	ENOG4108Z9W	Outer membrane porin
Varpa_1169	ENOG4108UKZ	OsmC family
Varpa_1170	ENOG4108S0N	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol (By similarity)
Varpa_1171	ENOG4108Z9W	Outer membrane porin
Varpa_1175	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
Varpa_1176	ENOG4105C3U	ABC transporter
Varpa_1177	ENOG4108JQ7	(ABC) transporter
Varpa_1179	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
Varpa_1180	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
Varpa_1181	ENOG4105C4Y	ABC transporter
Varpa_1182	ENOG4107RCV	ABC transporter, permease
Varpa_1183	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
Varpa_1186	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
Varpa_1187	ENOG4107QP8	phosphohexose isomerase
Varpa_1188	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
Varpa_1193	ENOG4105DRW	binding-protein-dependent transport systems inner membrane Component
Varpa_1194	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
Varpa_1195	ENOG4105DEI	Mannitol dehydrogenase
Varpa_1196	ENOG4105CHR	reductase
Varpa_1197	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
Varpa_1199	ENOG4105EQD	regulatoR
Varpa_1200	ENOG4105CMG	Carbohydrate kinase
Varpa_1201	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
Varpa_1202	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
Varpa_1204	ENOG4105DUM	transcriptional regulator, lysR family
Varpa_1207	ENOG4107RZC	phospholipase d
Varpa_1208	ENOG4105E0K	tonB-dependent siderophore receptor
Varpa_1211	ENOG4105CHB	tonB-dependent Receptor
Varpa_1212	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
Varpa_1214	ENOG4105D1S	lipid A biosynthesis
Varpa_1216	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
Varpa_1217	ENOG4106RE7	Cytochrome
Varpa_1218	ENOG4105EBH	Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment (By similarity)
Varpa_1219	ENOG4105CRE	cytochrome C
Varpa_1220	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
Varpa_1221	ENOG4105DQ2	Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity)
Varpa_1222	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
Varpa_1224	ENOG4105XQ6	frataxin-like protein
Varpa_1225	ENOG4108JQC	penicillin-binding protein 1A
Varpa_1230	ENOG4105E4G	Type IV pilus
Varpa_1231	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
Varpa_1232	ENOG4105D49	3-dehydroquinate synthase
Varpa_1233	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
Varpa_1240	ENOG4105DHJ	ABC, transporter
Varpa_1241	ENOG4105CY3	ABC transporter, permease
Varpa_1242	ENOG4107PE3	Mammalian cell entry related domain protein
Varpa_1246	ENOG4105DA5	(ABC) transporter
Varpa_1247	ENOG4105E3A	(ABC) transporter
Varpa_1248	ENOG4105VFK	BolA family
Varpa_1249	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
Varpa_1250	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
Varpa_1255	ENOG4105CIH	Imidazole acetol-phosphate transaminase
Varpa_1256	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
Varpa_1258	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
Varpa_1259	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
Varpa_1260	ENOG4107RP9	extracellular solute-binding protein, family 3
Varpa_1261	ENOG4105CK2	sodium dicarboxylate symporter
Varpa_1263	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
Varpa_1264	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
Varpa_1265	ENOG4105KPZ	phosphoribosyl-atp pyrophosphatase
Varpa_1267	ENOG4107YU2	histidine triad (hIT) protein
Varpa_1268	ENOG4105WKS	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
Varpa_1269	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
Varpa_1270	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
Varpa_1271	ENOG4105C0H	protease
Varpa_1272	ENOG4105CSH	Transporter
Varpa_1273	ENOG4107QNR	UPF0135 protein
Varpa_1274	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
Varpa_1275	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
Varpa_1276	ENOG4106YJS	accessory processing protein
Varpa_1278	ENOG4105WH1	Two component transcriptional regulator luxr family
Varpa_1279	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
Varpa_1280	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
Varpa_1281	ENOG4105EIX	cytochrome c1
Varpa_1282	ENOG4107MKT	Stringent starvation protein a
Varpa_1283	ENOG4105KB2	stringent starvation protein b
Varpa_1284	ENOG4105EMU	Dehydrogenase
Varpa_1286	ENOG4105VJY	transcriptional regulator
Varpa_1287	ENOG4105BZU	Histidine kinase
Varpa_1288	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
Varpa_1290	ENOG4105D60	lipoprotein releasing system transmembrane protein
Varpa_1291	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
Varpa_1292	ENOG4108KPJ	rna polymerase sigma factor
Varpa_1293	ENOG4108S10	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
Varpa_1294	ENOG4107YYT	May reduce aminoacrylate peracid to aminoacrylate. Required to remove a toxic intermediate produce by the pyrimidine nitrogen degradation (By similarity)
Varpa_1308	ENOG4107ZC0	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
Varpa_1310	ENOG4107RP9	extracellular solute-binding protein, family 3
Varpa_1315	ENOG4105JQZ	Methyltransferase
Varpa_1316	ENOG4108MEJ	flavin reductase domain protein
Varpa_1318	ENOG4105CHR	reductase
Varpa_1319	ENOG4105DXM	phenylacetic acid degradation protein
Varpa_1320	ENOG4108IV0	ABC, transporter
Varpa_1321	ENOG4105C0Z	ABC transporter
Varpa_1324	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
Varpa_1325	ENOG4108ZA2	phenylacetate-CoA oxygenase PaaJ subunit
Varpa_1326	ENOG4105D9S	phenylacetate-CoA oxygenase PaaI subunit
Varpa_1327	ENOG4105N76	Phenylacetate-CoA oxygenase, subunit
Varpa_1328	ENOG4105CRS	phenylacetate-CoA oxygenase PaaG subunit
Varpa_1330	ENOG4108ZJI	phenylacetic acid degradation protein
Varpa_1331	ENOG4108UKI	Enoyl-CoA hydratase
Varpa_1333	ENOG4108IG5	Transcriptional regulator
Varpa_1334	ENOG4107FW0	short-chain dehydrogenase reductase
Varpa_1336	ENOG4107QVM	von Willebrand factor, type A
Varpa_1338	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
Varpa_1339	ENOG4105C0H	protease
Varpa_1340	ENOG4105EYA	deoxyribonuclease
Varpa_1343	ENOG4105I7M	spermidine synthase
Varpa_1344	ENOG4107QHF	type ii secretion system protein e
Varpa_1347	ENOG4105F04	LysR family Transcriptional regulator
Varpa_1351	ENOG4105CHR	reductase
Varpa_1355	ENOG4108IAJ	Nad-dependent epimerase dehydratase
Varpa_1358	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
Varpa_1360	ENOG4105DHU	Bile acid
Varpa_1361	ENOG4105EAM	Na Pi-cotransporter
Varpa_1362	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
Varpa_1365	ENOG4108I5D	sulfate abc transporter
Varpa_1367	ENOG4105ETE	Transcriptional regulator (LacI family
Varpa_1368	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
Varpa_1370	ENOG4105DTN	riboflavin biosynthesis protein ribF
Varpa_1373	ENOG4108KTS	Acetyltransferase and hydrolase with the alpha beta hydrolase fold
Varpa_1375	ENOG4105X7H	acyl-CoA dehydrogenase
Varpa_1376	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
Varpa_1382	ENOG4105W0E	50S ribosomal protein L33
Varpa_1383	ENOG4105KDC	50s ribosomal protein l28
Varpa_1384	ENOG4105C3M	thioredoxin reductase
Varpa_1385	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
Varpa_1386	ENOG4105CNU	cell division protein FtsK
Varpa_1387	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
Varpa_1388	ENOG4105D1H	recombination factor protein RarA
Varpa_1389	ENOG4105C32	Amino acid ABC transporter (Permease)
Varpa_1390	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
Varpa_1391	ENOG4105C0Z	ABC transporter
Varpa_1392	ENOG4108IV0	ABC, transporter
Varpa_1397	ENOG4105C6T	cysteine synthase
Varpa_1398	ENOG4105E09	nadh pyrophosphatase
Varpa_1399	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
Varpa_1400	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
Varpa_1401	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
Varpa_1402	ENOG4105D1Q	UPF0246 protein
Varpa_1404	ENOG4106HB6	Alpha beta hydrolase
Varpa_1405	ENOG4105CSD	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
Varpa_1406	ENOG4105KF3	Short-chain dehydrogenase reductase Sdr
Varpa_1409	ENOG4105C1G	acyl-Coa dehydrogenase
Varpa_1411	ENOG4105D2B	acyl-CoA dehydrogenase
Varpa_1413	ENOG4105CEY	Amp-dependent synthetase and ligase
Varpa_1418	ENOG4105CXT	aspartate transcarbamylase
Varpa_1420	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
Varpa_1421	ENOG4107S01	Repressor protein MetJ
Varpa_1424	ENOG4106NZI	LysR family Transcriptional regulator
Varpa_1428	ENOG4105EQR	Transposase IS116 IS110 IS902
Varpa_1430	ENOG4108Z9W	Outer membrane porin
Varpa_1432	ENOG4105I7Z	Short-chain dehydrogenase reductase Sdr
Varpa_1435	ENOG4105CNN	ABC, transporter
Varpa_1437	ENOG4105DIA	mandelate racemase muconate lactonizing
Varpa_1438	ENOG4105CHR	reductase
Varpa_1441	ENOG4105CSH	Transporter
Varpa_1442	ENOG4105DMF	Dehydrogenase
Varpa_1443	ENOG4108PZW	LysR family Transcriptional regulator
Varpa_1444	ENOG4105DAA	L-lactate
Varpa_1447	ENOG4108V7B	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide (By similarity)
Varpa_1448	ENOG4105EMU	Dehydrogenase
Varpa_1453	ENOG4105WD1	Membrane
Varpa_1457	ENOG4105E9K	Isocitrate dehydrogenase
Varpa_1458	ENOG4105E0A	ABC, transporter
Varpa_1459	ENOG4105DJ2	Major Facilitator Superfamily
Varpa_1460	ENOG4105JXH	GntR family transcriptional regulator
Varpa_1462	ENOG4105HA9	of methanol dehydrogenase type
Varpa_1463	ENOG4105BZ4	penicillin-binding protein
Varpa_1465	ENOG410829K	Lysine exporter protein (Lyse ygga)
Varpa_1473	ENOG4108MP6	LysR family Transcriptional regulator
Varpa_1480	ENOG4108ZI4	Glyoxalase Bleomycin resistance protein (Dioxygenase
Varpa_1490	ENOG4108MVM	Transposase
Varpa_1491	ENOG4108ZQS	transposase
Varpa_1497	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
Varpa_1498	ENOG4105BZS	acriflavin resistance protein
Varpa_1499	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
Varpa_1501	ENOG4105CH7	arginosuccinase
Varpa_1502	ENOG4108HRK	Histidine kinase
Varpa_1503	ENOG4108NEV	two component transcriptional regulator, LytTR family
Varpa_1504	ENOG4105DSF	transport protein
Varpa_1505	ENOG4107YPT	transcriptional regulator
Varpa_1509	ENOG4105DUM	transcriptional regulator, lysR family
Varpa_1512	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
Varpa_1513	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
Varpa_1519	ENOG4105C03	ribonuclease
Varpa_1520	ENOG4105EI2	Pseudouridine synthase
Varpa_1523	ENOG4108E8C	) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
Varpa_1524	ENOG4106UW1	Major Facilitator superfamily
Varpa_1525	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
Varpa_1526	ENOG4108UHJ	MAF-like protein
Varpa_1527	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
Varpa_1528	ENOG4105VGS	50s ribosomal protein l32
Varpa_1529	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
Varpa_1530	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
Varpa_1531	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
Varpa_1532	ENOG4105CHR	reductase
Varpa_1533	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
Varpa_1534	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
Varpa_1536	ENOG4105EMN	RNA polymerase sigma factor
Varpa_1539	ENOG4105C0H	protease
Varpa_1540	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
Varpa_1541	ENOG4105C3F	Signal peptidase i
Varpa_1543	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
Varpa_1544	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
Varpa_1545	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
Varpa_1546	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
Varpa_1547	ENOG4105KJV	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
Varpa_1548	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
Varpa_1550	ENOG4108VKG	metal-dependent hydrolase
Varpa_1551	ENOG4105R8A	Heat shock protein
Varpa_1555	ENOG4105CRK	lysyL-tRNA synthetase
Varpa_1557	ENOG4108VIA	integral membrane protein
Varpa_1558	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
Varpa_1559	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
Varpa_1560	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
Varpa_1561	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
Varpa_1562	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
Varpa_1564	ENOG4107QJH	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
Varpa_1565	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
Varpa_1566	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
Varpa_1567	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
Varpa_1569	ENOG4105BZN	citrate synthase
Varpa_1570	ENOG41060IS	Flavinator of succinate dehydrogenase
Varpa_1571	ENOG4105E33	succinate dehydrogenase
Varpa_1575	ENOG4105FDP	GntR family transcriptional regulator
Varpa_1576	ENOG4105D9Z	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
Varpa_1577	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
Varpa_1580	ENOG4107QIJ	Aconitate hydratase 2
Varpa_1590	ENOG4107QPN	acyl-Coa dehydrogenase
Varpa_1593	ENOG4107QM5	aconitate hydratase
Varpa_1596	ENOG4105CE1	Ferrous iron transport protein b
Varpa_1598	ENOG4105MSY	salicylate hydroxylase
Varpa_1600	ENOG4107RRE	RNA-directed DNA polymerase
Varpa_1601	ENOG4105HJ8	Catalyzes the oxidative cleavage of the L-tryptophan (L- Trp) pyrrole ring (By similarity)
Varpa_1604	ENOG4107VWA	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation (By similarity)
Varpa_1606	ENOG4105DBV	ornithine carbamoyltransferase
Varpa_1607	ENOG4105C8Y	Acetylornithine aminotransferase
Varpa_1609	ENOG41082GY	Binds directly to 16S ribosomal RNA (By similarity)
Varpa_1610	ENOG4105CJR	Integral membrane protein (MviN
Varpa_1613	ENOG4105GRZ	Ycii-related protein
Varpa_1614	ENOG4105GRZ	Ycii-related protein
Varpa_1616	ENOG4105CHP	RNA polymerase
Varpa_1617	ENOG4105E7U	AraC family transcriptional regulator
Varpa_1621	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
Varpa_1622	ENOG4108KZ1	Mediates the interaction of DNA replication inititator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN). Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinititation, a process called regulatory inhibition of DnaA or RIDA (By similarity)
Varpa_1623	ENOG4105DJ0	Poly(A) Polymerase
Varpa_1624	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
Varpa_1625	ENOG4107GRR	phosphate transport regulator
Varpa_1626	ENOG4107QXV	Phosphate transporter
Varpa_1629	ENOG4105K5M	30s ribosomal protein S16
Varpa_1630	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
Varpa_1631	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
Varpa_1632	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
Varpa_1633	ENOG4105P8F	nudix hydrolase
Varpa_1634	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
Varpa_1635	ENOG4105E45	Histidinol-phosphate aminotransferase
Varpa_1636	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
Varpa_1637	ENOG41090A4	Pterin carbinolamine dehydratase
Varpa_1638	ENOG4105D0M	Protease HtpX homolog
Varpa_1639	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
Varpa_1640	ENOG4105C1J	atp-dependent rna helicase
Varpa_1641	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
Varpa_1642	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
Varpa_1643	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
Varpa_1649	ENOG4105FUY	alpha subunit
Varpa_1651	ENOG4105CEY	Amp-dependent synthetase and ligase
Varpa_1652	ENOG4105CHU	acetyl-coa acetyltransferase
Varpa_1654	ENOG4106IPI	cyclase, family
Varpa_1655	ENOG4105CHR	reductase
Varpa_1656	ENOG4105CP9	extracellular ligand-binding receptor
Varpa_1657	ENOG4105CP9	extracellular ligand-binding receptor
Varpa_1658	ENOG4105FUY	alpha subunit
Varpa_1659	ENOG4108SBK	dioxygenase, subunit beta
Varpa_1661	ENOG4105C32	Amino acid ABC transporter (Permease)
Varpa_1662	ENOG4105C0Z	ABC transporter
Varpa_1663	ENOG4108IV0	ABC, transporter
Varpa_1664	ENOG4105CEY	Amp-dependent synthetase and ligase
Varpa_1665	ENOG4105DTD	Dehydrogenase
Varpa_1673	ENOG4105CHR	reductase
Varpa_1675	ENOG4107SJ1	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides (By similarity)
Varpa_1676	ENOG4105C4R	Atp-dependent dna helicase
Varpa_1680	ENOG4105CUV	Homoserine Kinase
Varpa_1682	ENOG4105C2M	dna polymerase I
Varpa_1685	ENOG4105SB3	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
Varpa_1687	ENOG4105MDH	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
Varpa_1690	ENOG4105CNM	Receptor
Varpa_1692	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
Varpa_1693	ENOG4107RP9	extracellular solute-binding protein, family 3
Varpa_1695	ENOG4105CDZ	Carboxymethylenebutenolidase (EC 3.1.1.45)
Varpa_1705	ENOG4105FC8	fad dependent oxidoreductase
Varpa_1716	ENOG4108NST	exported protein
Varpa_1719	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
Varpa_1721	ENOG4105KHC	sulfurtransferase
Varpa_1724	ENOG41086K9	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
Varpa_1725	ENOG4105CTB	Polyprenyl synthetase
Varpa_1726	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
Varpa_1727	ENOG4105CH5	extracellular solute-binding protein, family 7
Varpa_1728	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
Varpa_1730	ENOG4105E46	N-alpha,N-alpha,N-alpha-trimethyl-L-histidine metabolic process
Varpa_1731	ENOG41079KZ	Major Facilitator Superfamily
Varpa_1735	ENOG4105C4Y	ABC transporter
Varpa_1740	ENOG4105CJP	fad dependent oxidoreductase
Varpa_1741	ENOG4105C26	Dehydrogenase
Varpa_1742	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
Varpa_1743	ENOG4105EVZ	LysR family transcriptional regulator
Varpa_1744	ENOG4108K85	Transcriptional regulator
Varpa_1746	ENOG4105C32	Amino acid ABC transporter (Permease)
Varpa_1748	ENOG4105C0Z	ABC transporter
Varpa_1749	ENOG4108IV0	ABC, transporter
Varpa_1750	ENOG4105CE7	Amidase, hydantoinase carbamoylase family
Varpa_1751	ENOG4107TSX	ABC branched chain amino acid family transporter periplasmic ligand binding protein
Varpa_1761	ENOG4107P0T	Selenium-dependent molybdenum hydroxylase system protein, YqeB family
Varpa_1762	ENOG4105KJM	monovalent cation h antiporter subunit g
Varpa_1763	ENOG4105W4C	monovalent cation H antiporter subunit F
Varpa_1765	ENOG4107R4Z	monovalent cation h antiporter subunit d
Varpa_1766	ENOG4108ZE9	Monovalent cation H antiporter subunit C
Varpa_1767	ENOG4105D65	subunit l
Varpa_1768	ENOG4107Z6W	Protein CrcB homolog
Varpa_1769	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
Varpa_1771	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
Varpa_1773	ENOG4105CFV	Tetratricopeptide repeat protein
Varpa_1776	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
Varpa_1777	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
Varpa_1780	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
Varpa_1782	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
Varpa_1783	ENOG4105UYK	outer membrane protein a
Varpa_1784	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
Varpa_1785	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
Varpa_1788	ENOG4106R49	Methyltransferase
Varpa_1790	ENOG4105I08	Pseudouridine synthase
Varpa_1796	ENOG4105C5F	glutamine synthetase
Varpa_1798	ENOG4105CUX	Signal transduction histidine kinase
Varpa_1799	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
Varpa_1801	ENOG4105CGK	Exodeoxyribonuclease III
Varpa_1804	ENOG4105CMJ	mandelate racemase muconate lactonizing
Varpa_1805	ENOG4105CHR	reductase
Varpa_1807	ENOG4105UVJ	5-dehydro-4-deoxyglucarate dehydratase
Varpa_1808	ENOG4107YNJ	LysR family Transcriptional regulator
Varpa_1810	ENOG4107UXM	Membrane
Varpa_1814	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
Varpa_1818	ENOG4105CQB	FAD linked oxidase domain protein
Varpa_1820	ENOG4107S2Z	UPF0761 membrane protein
Varpa_1822	ENOG4105K63	Thioredoxin
Varpa_1829	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
Varpa_1830	ENOG4106NZI	LysR family Transcriptional regulator
Varpa_1841	ENOG4105I1J	Autotransporter
Varpa_1851	ENOG4105CSH	Transporter
Varpa_1852	ENOG4108ZXC	Two component transcriptional regulator, luxr family
Varpa_1853	ENOG4105BZU	Histidine kinase
Varpa_1854	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
Varpa_1855	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
Varpa_1857	ENOG4107Z3H	Transcriptional regulator, TetR family
Varpa_1859	ENOG4105CD5	CoA-binding domain protein
Varpa_1860	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
Varpa_1863	ENOG4105CAU	Arsenical resistance protein, ArsH
Varpa_1865	ENOG4107R5R	arsenical pump membrane protein
Varpa_1866	ENOG41085FC	arsR family transcriptional regulator
Varpa_1869	ENOG4105HP8	regulator of competence-specific genes
Varpa_1870	ENOG4105KHA	Glyoxalase Bleomycin resistance protein (Dioxygenase
Varpa_1872	ENOG4105C4W	S-formylglutathione hydrolase
Varpa_1874	ENOG4107QPD	alcohol dehydrogenase
Varpa_1878	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
Varpa_1879	ENOG4105ED1	spovr family
Varpa_1880	ENOG4106AKX	UPF0229 protein
Varpa_1881	ENOG4105CYN	Serine protein kinase
Varpa_1882	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
Varpa_1883	ENOG4105CFG	Acts as a chaperone (By similarity)
Varpa_1884	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
Varpa_1885	ENOG4108V1T	peptidylprolyl cis-trans isomerase
Varpa_1887	ENOG4105DJ4	phosphatidylserine decarboxylase
Varpa_1889	ENOG4105HHQ	6-phosphogluconolactonase (EC 3.1.1.31)
Varpa_1891	ENOG4105CHR	reductase
Varpa_1892	ENOG4105CTX	dehydratase
Varpa_1895	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
Varpa_1897	ENOG4105E9Z	Nad-dependent epimerase dehydratase
Varpa_1898	ENOG4107YCY	Transcriptional regulator
Varpa_1900	ENOG4105UVJ	5-dehydro-4-deoxyglucarate dehydratase
Varpa_1905	ENOG4105C26	Dehydrogenase
Varpa_1906	ENOG4105E90	ABC transporter
Varpa_1909	ENOG4107QWP	ABC-2 type transporter
Varpa_1910	ENOG4107QWP	ABC-2 type transporter
Varpa_1911	ENOG4105CJ1	ABC, transporter
Varpa_1914	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
Varpa_1915	ENOG4108RXX	maleylacetoacetate isomerase
Varpa_1918	ENOG4108WYP	Transcriptional regulator
Varpa_1923	ENOG4105C0Z	ABC transporter
Varpa_1924	ENOG4108IV0	ABC, transporter
Varpa_1928	ENOG4108W5M	transcriptional regulator
Varpa_1929	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
Varpa_1930	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
Varpa_1934	ENOG4105C2C	drug resistance transporter, Bcr CflA
Varpa_1936	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
Varpa_1938	ENOG4107S2Z	UPF0761 membrane protein
Varpa_1940	ENOG4108WFY	phasin family
Varpa_1941	ENOG4105DGU	Histone deacetylase
Varpa_1944	ENOG4105VDW	Csbd family
Varpa_1945	ENOG4107RH7	Nicotinate phosphoribosyltransferase
Varpa_1947	ENOG4105C5I	Dehydrogenase
Varpa_1952	ENOG41067SE	Tetr family transcriptional regulator
Varpa_1953	ENOG4108URH	decarboxylase
Varpa_1954	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
Varpa_1957	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
Varpa_1958	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
Varpa_1961	ENOG4105EJC	lysr family transcriptional regulator
Varpa_1962	ENOG4105EBM	Alpha Beta Hydrolase Fold protein
Varpa_1963	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
Varpa_2004	ENOG4105WH1	Two component transcriptional regulator luxr family
Varpa_2005	ENOG4107R6F	Alpha Beta Hydrolase Fold protein
Varpa_2006	ENOG4105BZU	Histidine kinase
Varpa_2048	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
Varpa_2049	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
Varpa_2050	ENOG4108K5P	(LipO)protein
Varpa_2051	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
Varpa_2052	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
Varpa_2053	ENOG4108XRP	Membrane
Varpa_2054	ENOG4108ZJF	Glcg protein
Varpa_2056	ENOG4105M8F	Biopolymer transport protein exbD tolR
Varpa_2060	ENOG4107E2E	PKHD-type hydroxylase
Varpa_2061	ENOG4108IU3	tonb-dependent siderophore receptor
Varpa_2062	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
Varpa_2063	ENOG4105CJ2	(LipO)protein
Varpa_2067	ENOG4108UQY	Iron-storage protein
Varpa_2069	ENOG4108JU3	Alkyl hydroperoxide reductase
Varpa_2070	ENOG4105D05	Receptor
Varpa_2071	ENOG4106QJH	hemin transport protein
Varpa_2074	ENOG4105EHG	Permease protein
Varpa_2075	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
Varpa_2076	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
Varpa_2077	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
Varpa_2079	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
Varpa_2081	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
Varpa_2082	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
Varpa_2083	ENOG4105CDU	Replicative dna helicase
Varpa_2089	ENOG4108IAB	Phoh family
Varpa_2090	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
Varpa_2092	ENOG4105CHM	Aminotransferase
Varpa_2093	ENOG4105D6E	homoserine dehydrogenase
Varpa_2095	ENOG4105FNP	Molybdopterin-guanine dinucleotide biosynthesis protein b
Varpa_2096	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
Varpa_2098	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
Varpa_2099	ENOG4108ZAF	Molybdopterin
Varpa_2100	ENOG4105JN3	extra-cytoplasmic solute receptor family protein
Varpa_2101	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
Varpa_2103	ENOG4108IQE	Amp-dependent synthetase and ligase
Varpa_2104	ENOG4108IV0	ABC, transporter
Varpa_2108	ENOG4105C0Z	ABC transporter
Varpa_2110	ENOG4105CHU	acetyl-coa acetyltransferase
Varpa_2111	ENOG4108YZN	class I peptide chain release factor
Varpa_2112	ENOG4108RXX	maleylacetoacetate isomerase
Varpa_2113	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
Varpa_2117	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
Varpa_2118	ENOG4105EBR	Carboxylesterase
Varpa_2119	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
Varpa_2120	ENOG4105E39	Enoyl-CoA hydratase
Varpa_2124	ENOG4105HEI	LysR family (Transcriptional regulator
Varpa_2129	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
Varpa_2130	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
Varpa_2137	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
Varpa_2139	ENOG4106ZX3	phosphonate ABC transporter, periplasmic phosphonate-binding protein
Varpa_2140	ENOG4105D5T	phosphonate abc transporter
Varpa_2149	ENOG4105CHU	acetyl-coa acetyltransferase
Varpa_2152	ENOG4105ED9	Protein of unknown function (DUF455)
Varpa_2153	ENOG4108Z0R	Transferase
Varpa_2154	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
Varpa_2158	ENOG4105D5K	Hemolysin activator protein
Varpa_2161	ENOG4105CBZ	Short-chain dehydrogenase reductase Sdr
Varpa_2165	ENOG4106Z1T	Nicotinamide Mononucleotide Transporter
Varpa_2166	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
Varpa_2167	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
Varpa_2169	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
Varpa_2169	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
Varpa_2170	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
Varpa_2171	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
Varpa_2173	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
Varpa_2175	ENOG4108YZY	peptidylprolyl cis-trans isomerase
Varpa_2176	ENOG4105EZE	Cupin 4 family protein
Varpa_2179	ENOG4105Q2H	domain protein
Varpa_2180	ENOG4105GJM	(LipO)protein
Varpa_2181	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
Varpa_2185	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
Varpa_2186	ENOG4105E4C	Lytic transglycosylase catalytic
Varpa_2187	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
Varpa_2195	ENOG4105E5Q	amino acid AbC transporter
Varpa_2196	ENOG4105E5Q	amino acid AbC transporter
Varpa_2197	ENOG4105EAB	amino acid AbC transporter
Varpa_2198	ENOG4105CDA	abc transporter atp-binding protein
Varpa_2200	ENOG4105D7K	pfkb domain protein
Varpa_2201	ENOG4105C5I	Dehydrogenase
Varpa_2202	ENOG4108M60	Transcriptional regulator
Varpa_2206	ENOG4105F04	LysR family Transcriptional regulator
Varpa_2210	ENOG4106PMH	Extracellular solute-binding protein family 3
Varpa_2213	ENOG4108EC8	DNA internalization-related competence protein ComEC
Varpa_2219	ENOG4105DIJ	Phosphoethanolamine transferase
Varpa_2221	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
Varpa_2222	ENOG4105E98	transcriptional regulator DeoR family
Varpa_2223	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
Varpa_2224	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
Varpa_2225	ENOG4108IJ9	(ABC) transporter
Varpa_2227	ENOG4105EB1	binding-protein-dependent transport systems inner membrane Component
Varpa_2234	ENOG4105CJ1	ABC, transporter
Varpa_2240	ENOG4105CVE	Lytic murein transglycosylase
Varpa_2241	ENOG4105F8C	transglutaminase domain-containing protein
Varpa_2243	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
Varpa_2244	ENOG4105DGU	Histone deacetylase
Varpa_2245	ENOG4105EGS	Mechanosensitive ion channel
Varpa_2246	ENOG4105BZJ	Electron transfer flavoprotein
Varpa_2247	ENOG4105C10	Electron transfer flavoprotein
Varpa_2248	ENOG4105CSU	acyl-Coa dehydrogenase
Varpa_2252	ENOG4105CEY	Amp-dependent synthetase and ligase
Varpa_2254	ENOG410900P	UPF0336 protein
Varpa_2256	ENOG4105CHR	reductase
Varpa_2257	ENOG4108UKI	Enoyl-CoA hydratase
Varpa_2262	ENOG4105GRZ	Ycii-related protein
Varpa_2264	ENOG4105C57	major facilitator superfamily
Varpa_2266	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
Varpa_2268	ENOG4107R5G	Periplasmic binding protein LacI transcriptional regulator
Varpa_2269	ENOG4105CNN	ABC, transporter
Varpa_2270	ENOG4105C2J	ABC transporter
Varpa_2276	ENOG4105DIQ	Transcriptional regulator
Varpa_2277	ENOG4105CPQ	Dehydrogenase
Varpa_2278	ENOG4105C5I	Dehydrogenase
Varpa_2279	ENOG4105CHR	reductase
Varpa_2280	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
Varpa_2282	ENOG41090VV	Protein of unknown function (DUF2846)
Varpa_2286	ENOG4105DHQ	Histidine kinase
Varpa_2287	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
Varpa_2290	ENOG41065U4	response regulator
Varpa_2292	ENOG4107HP6	Transcriptional regulator
Varpa_2293	ENOG4105E2X	shikimate dehydrogenase
Varpa_2294	ENOG4107V59	shikimate
Varpa_2295	ENOG4107RAW	3-carboxy-cis-cis-muconate cycloisomerase
Varpa_2297	ENOG4105C2C	drug resistance transporter, Bcr CflA
Varpa_2299	ENOG4105E6K	4-Hydroxyphenylpyruvate dioxygenase
Varpa_2300	ENOG4105CSH	Transporter
Varpa_2304	ENOG4105CPT	Alpha beta hydrolase
Varpa_2310	ENOG4106IUH	DTW domain containing protein
Varpa_2317	ENOG4108ZQS	transposase
Varpa_2319	ENOG4105J1P	transposase, IS3 IS911 family protein
Varpa_2326	ENOG4107QWG	2-Nitropropane dioxygenase
Varpa_2330	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
Varpa_2331	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
Varpa_2332	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
Varpa_2336	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
Varpa_2338	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
Varpa_2339	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
Varpa_2340	ENOG4105CHR	reductase
Varpa_2344	ENOG4105DHQ	Histidine kinase
Varpa_2345	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
Varpa_2347	ENOG4105D1E	Undecaprenyl pyrophosphate phosphatase
Varpa_2355	ENOG4108K3A	Glutathione S-transferase
Varpa_2359	ENOG4107FQ9	ethanolamine ammonia-lyase
Varpa_2360	ENOG4105CPD	ethanolamine ammonia-lyase
Varpa_2361	ENOG4105CUB	amino acid
Varpa_2362	ENOG4108V1T	peptidylprolyl cis-trans isomerase
Varpa_2363	ENOG4105CBZ	Short-chain dehydrogenase reductase Sdr
Varpa_2376	ENOG4109025	Glyoxalase Bleomycin resistance protein (Dioxygenase
Varpa_2379	ENOG4108KX4	response regulator
Varpa_2383	ENOG4105CHM	Aminotransferase
Varpa_2387	ENOG4105C26	Dehydrogenase
Varpa_2390	ENOG4105E39	Enoyl-CoA hydratase
Varpa_2391	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
Varpa_2395	ENOG4105ETT	transcriptional Regulator, LysR family
Varpa_2396	ENOG4105DZ2	Transcriptional regulator
Varpa_2397	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
Varpa_2402	ENOG4108R3E	Dna-3-methyladenine glycosylase i
Varpa_2404	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
Varpa_2408	ENOG4107SQI	penicillin amidase
Varpa_2409	ENOG4105CYM	Glutathione S-transferase
Varpa_2410	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
Varpa_2411	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
Varpa_2414	ENOG4105MHT	Transcriptional regulator, ARSR family
Varpa_2416	ENOG4108UT2	hemolysin iii
Varpa_2418	ENOG4107SQD	Transcriptional regulator, GntR family
Varpa_2421	ENOG4108UVJ	appr-1-p processing domain protein
Varpa_2422	ENOG4108ERU	trap dicarboxylate transporter subunit DctP
Varpa_2424	ENOG4107RP9	extracellular solute-binding protein, family 3
Varpa_2426	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
Varpa_2427	ENOG4105KD1	integral membrane protein
Varpa_2430	ENOG4108IG5	Transcriptional regulator
Varpa_2432	ENOG4105BZ1	(ABC) transporter
Varpa_2434	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
Varpa_2436	ENOG4105CPW	cytochrome b561
Varpa_2441	ENOG4107F83	nucleotidyltransferase DNA polymerase involved in DNA
Varpa_2442	ENOG4105C0B	DNA polymerase III (alpha subunit)
Varpa_2448	ENOG4105EJC	lysr family transcriptional regulator
Varpa_2450	ENOG4105EGI	Transcriptional regulator
Varpa_2451	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
Varpa_2452	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
Varpa_2454	ENOG4105EBR	Carboxylesterase
Varpa_2456	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
Varpa_2459	ENOG4108IG5	Transcriptional regulator
Varpa_2460	ENOG4105CIS	alcohol dehydrogenase
Varpa_2467	ENOG4107QZF	nitrite reductase NADPH large subunit
Varpa_2468	ENOG4105WZK	nitrite reductase NADPH small subunit
Varpa_2469	ENOG4105TMB	Formate nitrite transporter
Varpa_2470	ENOG4105D9P	serine threonine protein kinase
Varpa_2480	ENOG4105FDP	GntR family transcriptional regulator
Varpa_2482	ENOG4105CYM	Glutathione S-transferase
Varpa_2484	ENOG4108JU3	Alkyl hydroperoxide reductase
Varpa_2488	ENOG4105C9X	ppx gppa phosphatase
Varpa_2489	ENOG4107QMV	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
Varpa_2490	ENOG4105C8U	phosphate abc transporter
Varpa_2491	ENOG4105E2Z	phosphate ABC transporter (Permease
Varpa_2492	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
Varpa_2494	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
Varpa_2495	ENOG4105BZU	Histidine kinase
Varpa_2496	ENOG4107QI1	Mate efflux family protein
Varpa_2498	ENOG4105NRA	50s ribosomal protein l31 type b
Varpa_2499	ENOG4105D9R	oxidoreductase
Varpa_2500	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
Varpa_2501	ENOG4105K63	Thioredoxin
Varpa_2503	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
Varpa_2505	ENOG4107QMP	dna polymerase iii subunits gamma and tau
Varpa_2506	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
Varpa_2507	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
Varpa_2509	ENOG4105D2X	ABC transporter substrate-binding protein
Varpa_2511	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
Varpa_2512	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
Varpa_2513	ENOG4105E9H	Lytic Murein transglycosylase
Varpa_2514	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
Varpa_2515	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
Varpa_2516	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
Varpa_2517	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
Varpa_2518	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
Varpa_2519	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
Varpa_2522	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
Varpa_2524	ENOG4105C26	Dehydrogenase
Varpa_2526	ENOG4107RZC	phospholipase d
Varpa_2536	ENOG4108UYU	AsnC family transcriptional regulator
Varpa_2540	ENOG4105F0N	pyrophosphate phospho-hydrolase
Varpa_2543	ENOG4105C4K	Nad synthetase
Varpa_2544	ENOG4108YZA	Nitrogen regulatory protein pii
Varpa_2545	ENOG4108URH	decarboxylase
Varpa_2546	ENOG41080IJ	Diacylglycerol kinase
Varpa_2551	ENOG4105C7K	acetolactate synthase
Varpa_2552	ENOG4108ZP8	Acetolactate synthase small subunit
Varpa_2554	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
Varpa_2555	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
Varpa_2556	ENOG4107QXN	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
Varpa_2557	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
Varpa_2558	ENOG41061WM	D-Alanyl-D-Alanine
Varpa_2559	ENOG41069M3	Transcriptional regulator
Varpa_2560	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
Varpa_2561	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
Varpa_2566	ENOG41072AC	4-hydroxybenzoate 3-monooxygenase
Varpa_2567	ENOG4107HP6	Transcriptional regulator
Varpa_2568	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
Varpa_2569	ENOG4105DHQ	Histidine kinase
Varpa_2570	ENOG4105C0H	protease
Varpa_2573	ENOG4105WH1	Two component transcriptional regulator luxr family
Varpa_2580	ENOG4105KHM	amidohydrolase 2
Varpa_2581	ENOG4107F9Y	LysR family transcriptional regulator
Varpa_2585	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
Varpa_2593	ENOG4108R85	Short chain dehydrogenase
Varpa_2594	ENOG4105C5X	domain protein
Varpa_2598	ENOG4108K5P	(LipO)protein
Varpa_2603	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
Varpa_2608	ENOG4108T5G	Adenylate
Varpa_2611	ENOG4105CAY	ferredoxin--nadp reductase
Varpa_2612	ENOG4108Z4U	Ferredoxin
Varpa_2613	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
Varpa_2615	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
Varpa_2621	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
Varpa_2622	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
Varpa_2623	ENOG4105DEF	Extracellular solute-binding protein, family 5
Varpa_2624	ENOG4108JQ6	ABC transporter
Varpa_2625	ENOG4105D44	asparaginase
Varpa_2632	ENOG4105CPC	Aldo Keto reductase
Varpa_2633	ENOG4108PZW	LysR family Transcriptional regulator
Varpa_2638	ENOG4105D2S	major facilitator superfamily
Varpa_2639	ENOG4105CHR	reductase
Varpa_2640	ENOG4105CHR	reductase
Varpa_2642	ENOG4105CKI	cobalamin synthesis protein
Varpa_2644	ENOG4107414	GntR family transcriptional regulator
Varpa_2645	ENOG4107R1Y	fructose-bisphosphate aldolase
Varpa_2646	ENOG4105CYC	Transferase
Varpa_2647	ENOG4108RVA	ribokinase
Varpa_2648	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
Varpa_2649	ENOG4105C2J	ABC transporter
Varpa_2650	ENOG4105MN5	HAD-superfamily hydrolase subfamily IA variant 3
Varpa_2651	ENOG4105CNN	ABC, transporter
Varpa_2654	ENOG4105E98	transcriptional regulator DeoR family
Varpa_2655	ENOG4107U7B	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
Varpa_2657	ENOG4105EQW	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
Varpa_2658	ENOG4108S1C	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
Varpa_2659	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
Varpa_2660	ENOG4105BZU	Histidine kinase
Varpa_2665	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
Varpa_2666	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
Varpa_2667	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
Varpa_2668	ENOG4108UZX	fmn reductase
Varpa_2670	ENOG4105GVF	(ABC) transporter
Varpa_2671	ENOG4105D4R	Catalyzes the desulfonation of aliphatic sulfonates (By similarity)
Varpa_2672	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
Varpa_2673	ENOG4105GVF	(ABC) transporter
Varpa_2674	ENOG4105E2Y	ABC, transporter
Varpa_2682	ENOG4105D7W	serine acetyltransferase
Varpa_2684	ENOG4105ESN	nucleotide-binding protein
Varpa_2685	ENOG4105C9B	Cysteine desulfurase
Varpa_2687	ENOG4105EUP	HipA domain protein
Varpa_2689	ENOG41063V1	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
Varpa_2691	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
Varpa_2692	ENOG4105JQN	Transcriptional regulator
Varpa_2693	ENOG4105D3R	alkyl hydroperoxide reductase
Varpa_2695	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
Varpa_2696	ENOG4108I5D	sulfate abc transporter
Varpa_2697	ENOG4105ECW	sulfate abc transporter
Varpa_2698	ENOG4108IJ6	ABC transporter
Varpa_2699	ENOG410635M	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
Varpa_2700	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
Varpa_2702	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
Varpa_2706	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
Varpa_2707	ENOG4105CDY	transcriptional regulatory protein
Varpa_2708	ENOG4105C12	Phosphoribosylglycinamide synthetase
Varpa_2709	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
Varpa_2710	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
Varpa_2711	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
Varpa_2712	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
Varpa_2714	ENOG4108Z03	MAF-like protein
Varpa_2715	ENOG4105C03	ribonuclease
Varpa_2716	ENOG4105BZ1	(ABC) transporter
Varpa_2717	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
Varpa_2718	ENOG4105KCK	Peptidoglycan-associated lipoprotein
Varpa_2720	ENOG4105CUZ	uba thif-type nad fad binding protein
Varpa_2756	ENOG4105KK6	nuclease
Varpa_2769	ENOG4105J1P	transposase, IS3 IS911 family protein
Varpa_2773	ENOG4105C9U	ATP-dependent DNA helicase RecQ
Varpa_2790	ENOG4107S11	squalene-associated FAD-dependent desaturase
Varpa_2795	ENOG4105FDF	Could be involved in DNA repair (By similarity)
Varpa_2796	ENOG4105DQE	DNA ligase
Varpa_2798	ENOG4105FDF	Could be involved in DNA repair (By similarity)
Varpa_2800	ENOG4107S5I	aldo keto reductase
Varpa_2801	ENOG4105EQ2	LysR family Transcriptional regulator
Varpa_2810	ENOG4105C5H	ABC transporter
Varpa_2811	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
Varpa_2812	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
Varpa_2813	ENOG4105CZX	twitching motility protein
Varpa_2814	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
Varpa_2817	ENOG410829K	Lysine exporter protein (Lyse ygga)
Varpa_2818	ENOG4108EKC	n-acetylglutamate synthase
Varpa_2819	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
Varpa_2820	ENOG4105CQ7	ATP-dependent helicase
Varpa_2824	ENOG4105CHM	Aminotransferase
Varpa_2825	ENOG4107R11	Transcriptional regulator
Varpa_2827	ENOG4108K5H	permease YjgP YjgQ family protein
Varpa_2829	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
Varpa_2832	ENOG4105CP9	extracellular ligand-binding receptor
Varpa_2839	ENOG4105CXN	decarboxylase
Varpa_2841	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
Varpa_2843	ENOG4108I5X	binding-protein-dependent transport systems inner membrane Component
Varpa_2844	ENOG4108IYQ	Binding-protein-dependent transport systems inner membrane component
Varpa_2845	ENOG4108JQ5	ABC transporter
Varpa_2846	ENOG4105CBP	Major Facilitator
Varpa_2847	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
Varpa_2848	ENOG4105CHV	Transcription elongation factor NusA
Varpa_2850	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
Varpa_2851	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
Varpa_2852	ENOG4105CI3	gtp-binding protein typa
Varpa_2859	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
Varpa_2860	ENOG4108Z1B	Cyclase dehydrase
Varpa_2863	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
Varpa_2866	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
Varpa_2869	ENOG4105C0K	Gdp-mannose 4,6-dehydratase
Varpa_2874	ENOG4105CMR	udp-glucose 4-epimerase
Varpa_2875	ENOG4106CD9	glycosyl transferase group 1
Varpa_2881	ENOG4105C30	Nad-dependent epimerase dehydratase
Varpa_2887	ENOG4105CEY	Amp-dependent synthetase and ligase
Varpa_2890	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
Varpa_2896	ENOG4105CS6	Rhs element vgr protein
Varpa_2906	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
Varpa_2907	ENOG4105CS6	Rhs element vgr protein
Varpa_2908	ENOG4105CS6	Rhs element vgr protein
Varpa_2909	ENOG4105CS6	Rhs element vgr protein
Varpa_2920	ENOG4106VK6	Flagellar motor protein
Varpa_2923	ENOG4107QPV	Serine Threonine protein kinase
Varpa_2926	ENOG4105EWI	Short-chain dehydrogenase reductase Sdr
Varpa_2928	ENOG4105EUB	pirin domain protein
Varpa_2929	ENOG4105CC0	LysR family Transcriptional regulator
Varpa_2941	ENOG4108ZXC	Two component transcriptional regulator, luxr family
Varpa_2946	ENOG4108Z6B	deaminase
Varpa_2947	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
Varpa_2957	ENOG4107Z5C	methylesterase
Varpa_2958	ENOG4105BZU	Histidine kinase
Varpa_2959	ENOG4105BZU	Histidine kinase
Varpa_2960	ENOG4105DVT	helicase
Varpa_2967	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
Varpa_2968	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
Varpa_2971	ENOG4105CPC	Aldo Keto reductase
Varpa_2972	ENOG4105CF7	AraC family transcriptional regulator
Varpa_2974	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
Varpa_2978	ENOG4105CPC	Aldo Keto reductase
Varpa_2979	ENOG4105WKW	Pfam:DUF1458
Varpa_2982	ENOG4105KHC	sulfurtransferase
Varpa_2988	ENOG4105CD5	CoA-binding domain protein
Varpa_2989	ENOG4105D6E	homoserine dehydrogenase
Varpa_2993	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
Varpa_2994	ENOG4105WH1	Two component transcriptional regulator luxr family
Varpa_3003	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
Varpa_3004	ENOG4107S9Q	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB (By similarity)
Varpa_3005	ENOG4105CG3	alpha amylase, catalytic region
Varpa_3008	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
Varpa_3009	ENOG4107RTM	4-alpha-glucanotransferase (EC 2.4.1.25)
Varpa_3010	ENOG4105BZ9	Cytochrome C oxidase, subunit I
Varpa_3011	ENOG4105CV4	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
Varpa_3021	ENOG4108X0B	nad(p)h dehydrogenase (quinone)
Varpa_3025	ENOG4105E2A	Dehydrogenase
Varpa_3031	ENOG4107JEE	Short-chain dehydrogenase reductase Sdr
Varpa_3035	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
Varpa_3036	ENOG4105C4M	(Ubiquinol oxidase) subunit I
Varpa_3041	ENOG4105BZ1	(ABC) transporter
Varpa_3042	ENOG4107S11	squalene-associated FAD-dependent desaturase
Varpa_3046	ENOG4105WG9	Conserved Protein
Varpa_3050	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
Varpa_3051	ENOG4108IAJ	Nad-dependent epimerase dehydratase
Varpa_3055	ENOG4108IAJ	Nad-dependent epimerase dehydratase
Varpa_3057	ENOG4105CK5	oxidoreductase
Varpa_3062	ENOG4105PFA	Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity)
Varpa_3065	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
Varpa_3067	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
Varpa_3068	ENOG4105BZU	Histidine kinase
Varpa_3069	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
Varpa_3071	ENOG4105WEF	catalase
Varpa_3072	ENOG4105CEV	competence damage-inducible protein
Varpa_3074	ENOG4105CAY	ferredoxin--nadp reductase
Varpa_3084	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
Varpa_3086	ENOG4107JEE	Short-chain dehydrogenase reductase Sdr
Varpa_3093	ENOG4108Z9Z	response to DNA damage stimulus
Varpa_3094	ENOG4105D74	hydrolase
Varpa_3100	ENOG4105F8V	Hydrolase, tatD family
Varpa_3102	ENOG4107QRG	dna polymerase iii
Varpa_3103	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
Varpa_3104	ENOG4105HHA	aminodeoxychorismate lyase
Varpa_3105	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
Varpa_3114	ENOG4105BZM	domain protein
Varpa_3115	ENOG4105BZU	Histidine kinase
Varpa_3116	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
Varpa_3123	ENOG4107QJQ	Mate efflux family protein
Varpa_3125	ENOG4105E0K	tonB-dependent siderophore receptor
Varpa_3126	ENOG4108S3W	Anti-feci sigma factor, fecr
Varpa_3127	ENOG4108SF5	RNA Polymerase
Varpa_3129	ENOG4105ETE	Transcriptional regulator (LacI family
Varpa_3134	ENOG4105DY2	Paraquat-inducible protein b
Varpa_3135	ENOG4105F1S	paraquat-inducible protein a
Varpa_3136	ENOG4105F1S	paraquat-inducible protein a
Varpa_3137	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
Varpa_3138	ENOG4105C2C	drug resistance transporter, Bcr CflA
Varpa_3140	ENOG4105D0M	Protease HtpX homolog
Varpa_3143	ENOG4105ER2	Ompa motb domain protein
Varpa_3148	ENOG4105ETT	transcriptional Regulator, LysR family
Varpa_3150	ENOG4105HEI	LysR family (Transcriptional regulator
Varpa_3155	ENOG4105E0K	tonB-dependent siderophore receptor
Varpa_3156	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
Varpa_3157	ENOG4105CBP	Major Facilitator
Varpa_3158	ENOG4105CQB	FAD linked oxidase domain protein
Varpa_3163	ENOG4105HEI	LysR family (Transcriptional regulator
Varpa_3164	ENOG4105F27	Major Facilitator
Varpa_3168	ENOG4107U5X	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
Varpa_3176	ENOG4105CSU	acyl-Coa dehydrogenase
Varpa_3177	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
Varpa_3179	ENOG4105CHR	reductase
Varpa_3182	ENOG4105CSU	acyl-Coa dehydrogenase
Varpa_3184	ENOG4105CHU	acetyl-coa acetyltransferase
Varpa_3185	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
Varpa_3186	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
Varpa_3187	ENOG4108IV0	ABC, transporter
Varpa_3188	ENOG4105C0Z	ABC transporter
Varpa_3190	ENOG4105C32	Amino acid ABC transporter (Permease)
Varpa_3193	ENOG4105CEY	Amp-dependent synthetase and ligase
Varpa_3196	ENOG4105CNG	UPF0061 protein
Varpa_3197	ENOG4105E0X	reductase
Varpa_3198	ENOG4107835	probably involved in intracellular septation (By similarity)
Varpa_3200	ENOG4107TF3	peptidylprolyl cis-trans isomerase
Varpa_3201	ENOG4108ETH	Formylglycinamide ribotide synthetase
Varpa_3202	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
Varpa_3203	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
Varpa_3204	ENOG410620I	Diguanylate cyclase
Varpa_3207	ENOG4107QMS	site-determining protein
Varpa_3208	ENOG4107QZ7	Cellulose synthase catalytic subunit
Varpa_3209	ENOG4107EEX	Cellulose synthase regulator protein
Varpa_3210	ENOG4105K2Z	endo-1,4-d-glucanase (EC 3.2.1.4)
Varpa_3211	ENOG4105EJG	cellulose synthase
Varpa_3212	ENOG4105BZU	Histidine kinase
Varpa_3216	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
Varpa_3217	ENOG4105DRP	amino acid AbC transporter
Varpa_3218	ENOG4105EZ7	amino acid ABC transporter
Varpa_3219	ENOG4107QXX	ABC transporter
Varpa_3221	ENOG4108RBJ	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
Varpa_3223	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
Varpa_3225	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
Varpa_3237	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
Varpa_3240	ENOG4105D7A	ATP-binding protein
Varpa_3242	ENOG4105NCT	RNA Polymerase
Varpa_3247	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
Varpa_3248	ENOG4107TFB	basic membrane
Varpa_3249	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
Varpa_3251	ENOG4108JQ9	ABC transporter
Varpa_3252	ENOG4105UIB	(ABC) transporter
Varpa_3256	ENOG4108EJ0	Catalyzes the synthesis of activated sulfate (By similarity)
Varpa_3257	ENOG4105DZC	cytosine deaminase
Varpa_3261	ENOG4105CJB	Exodeoxyribonuclease I
Varpa_3262	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
Varpa_3263	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
Varpa_3264	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
Varpa_3274	ENOG4108WC9	type VI secretion system effector, hcp1 family
Varpa_3277	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
Varpa_3282	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
Varpa_3283	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
Varpa_3285	ENOG4108ZZF	transport protein (ExbD)
Varpa_3286	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
Varpa_3287	ENOG4105W49	UPF0434 protein
Varpa_3288	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
Varpa_3289	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
Varpa_3290	ENOG4105HDK	L-asparaginase
Varpa_3291	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
Varpa_3293	ENOG4108M3J	Dehydrogenase
Varpa_3294	ENOG4105F27	Major Facilitator
Varpa_3295	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
Varpa_3296	ENOG4105E39	Enoyl-CoA hydratase
Varpa_3297	ENOG4105IJJ	transcriptional regulator, crp fnr family
Varpa_3301	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
Varpa_3302	ENOG4105EEI	dihydropteroate synthase
Varpa_3303	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
Varpa_3304	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
Varpa_3305	ENOG4105HBR	Rna-binding protein
Varpa_3308	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
Varpa_3310	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
Varpa_3313	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
Varpa_3314	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
Varpa_3315	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
Varpa_3316	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
Varpa_3317	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
Varpa_3319	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
Varpa_3320	ENOG4105DZP	Membrane-associated zinc metalloprotease
Varpa_3321	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
Varpa_3322	ENOG4105KNE	Phosphatidate cytidylyltransferase
Varpa_3324	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
Varpa_3325	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
Varpa_3326	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
Varpa_3327	ENOG4105CE9	30S ribosomal protein S2
Varpa_3331	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
Varpa_3332	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
Varpa_3333	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
Varpa_3334	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
Varpa_3335	ENOG4108NVM	synthesis repressor PhaR
Varpa_3336	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
Varpa_3338	ENOG4105DTD	Dehydrogenase
Varpa_3340	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
Varpa_3341	ENOG4105E0F	Histidine kinase
Varpa_3342	ENOG4108ECM	Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl- D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2- phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4- cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF) (By similarity)
Varpa_3343	ENOG4108ECM	Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl- D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2- phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4- cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF) (By similarity)
Varpa_3344	ENOG4108JA2	transcriptioN-repair coupling factor
Varpa_3345	ENOG4105EAC	phosphoserine phosphatase
Varpa_3349	ENOG4108S3W	Anti-feci sigma factor, fecr
Varpa_3351	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
Varpa_3352	ENOG4105CSM	endonuclease III
Varpa_3355	ENOG4108UHF	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
Varpa_3356	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
Varpa_3357	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
Varpa_3359	ENOG4105ETP	RND efflux system, outer membrane lipoprotein
Varpa_3361	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
Varpa_3365	ENOG41067MG	lrgb family
Varpa_3372	ENOG4105E7Q	Cob(II)yrinic acid a,c-diamide reductase
Varpa_3373	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
Varpa_3374	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
Varpa_3375	ENOG4105EHG	Permease protein
Varpa_3377	ENOG4108YZT	Adenosylcobinamide kinase
Varpa_3378	ENOG4105C0Y	Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
Varpa_3382	ENOG4105HF0	Membrane
Varpa_3384	ENOG4105ECQ	AraC Family Transcriptional Regulator
Varpa_3385	ENOG4105ES4	Nitrilase
Varpa_3391	ENOG4105CEY	Amp-dependent synthetase and ligase
Varpa_3392	ENOG41060WC	Enoyl-CoA hydratase
Varpa_3395	ENOG4105DRR	Transcriptional regulator, GntR family
Varpa_3396	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
Varpa_3398	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
Varpa_3399	ENOG4105CBN	LysR family transcriptional regulator
Varpa_3400	ENOG4106NZI	LysR family Transcriptional regulator
Varpa_3401	ENOG4105C01	Dihydroxy-acid dehydratase
Varpa_3404	ENOG4105W2Z	cytochrome C, class I
Varpa_3406	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
Varpa_3407	ENOG4108TEB	UPF0114 protein
Varpa_3408	ENOG4105EJC	lysr family transcriptional regulator
Varpa_3409	ENOG4108RYK	Nad-dependent epimerase dehydratase
Varpa_3411	ENOG4108IJ7	Glycine betaine
Varpa_3412	ENOG4108HQS	Glycine betaine
Varpa_3413	ENOG4105GIJ	Glycine betaine
Varpa_3415	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
Varpa_3420	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
Varpa_3421	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
Varpa_3422	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
Varpa_3423	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
Varpa_3425	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
Varpa_3428	ENOG4105FE1	phytoene synthase
Varpa_3430	ENOG4105CVN	desaturase
Varpa_3434	ENOG4105DFC	had-superfamily hydrolase, subfamily ia, variant
Varpa_3435	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
Varpa_3441	ENOG4108IV0	ABC, transporter
Varpa_3443	ENOG4105C0Z	ABC transporter
Varpa_3457	ENOG4105DHQ	Histidine kinase
Varpa_3458	ENOG4105VEJ	Heat shock protein
Varpa_3459	ENOG4105CSR	polyphosphate kinase 2
Varpa_3462	ENOG4105W2Z	cytochrome C, class I
Varpa_3472	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
Varpa_3474	ENOG4108ZK4	sdia-regulated domain-containing protein
Varpa_3475	ENOG4108IV0	ABC, transporter
Varpa_3477	ENOG4105CNN	ABC, transporter
Varpa_3478	ENOG4105C32	Amino acid ABC transporter (Permease)
Varpa_3479	ENOG4105C0Z	ABC transporter
Varpa_3480	ENOG4105FBW	Monooxygenase
Varpa_3481	ENOG4108UZX	fmn reductase
Varpa_3483	ENOG4107T8P	acyl-Coa dehydrogenase
Varpa_3484	ENOG4107T8P	acyl-Coa dehydrogenase
Varpa_3487	ENOG4105D56	permease protein
Varpa_3489	ENOG4107T8P	acyl-Coa dehydrogenase
Varpa_3491	ENOG4107T8P	acyl-Coa dehydrogenase
Varpa_3492	ENOG4107SM7	Transcriptional regulator
Varpa_3494	ENOG4107RGH	Aldehyde dehydrogenase
Varpa_3498	ENOG4108Z9W	Outer membrane porin
Varpa_3499	ENOG4105HSS	phospholipase C
Varpa_3501	ENOG4105CFH	Aspartokinase
Varpa_3502	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
Varpa_3503	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
Varpa_3505	ENOG4105C8N	cysteinyl-tRNA synthetase
Varpa_3508	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
Varpa_3509	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
Varpa_3513	ENOG4106S48	Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division
Varpa_3514	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
Varpa_3515	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
Varpa_3522	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
Varpa_3523	ENOG4108R6K	riboflavin synthase, subunit alpha
Varpa_3524	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
Varpa_3525	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
Varpa_3526	ENOG4107YIM	Involved in the transcription termination process (By similarity)
Varpa_3527	ENOG4105CHM	Aminotransferase
Varpa_3528	ENOG4107YD3	Thioesterase
Varpa_3529	ENOG4105E02	MotA TolQ exbB proton channel
Varpa_3530	ENOG4108ZZF	transport protein (ExbD)
Varpa_3532	ENOG4105CJN	penicillin-binding protein
Varpa_3536	ENOG4105C0B	DNA polymerase III (alpha subunit)
Varpa_3537	ENOG4105C72	UPF0176 protein
Varpa_3539	ENOG4105DHQ	Histidine kinase
Varpa_3543	ENOG4105EUB	pirin domain protein
Varpa_3545	ENOG4108SB3	DoxX Family
Varpa_3549	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
Varpa_3550	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
Varpa_3553	ENOG4105IJJ	transcriptional regulator, crp fnr family
Varpa_3555	ENOG4105MP9	class II Aldolase
Varpa_3557	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
Varpa_3562	ENOG4108IV0	ABC, transporter
Varpa_3563	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
Varpa_3566	ENOG4107TSX	ABC branched chain amino acid family transporter periplasmic ligand binding protein
Varpa_3567	ENOG4105BZU	Histidine kinase
Varpa_3568	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
Varpa_3571	ENOG4108M0I	Transcriptional regulator
Varpa_3575	ENOG4105BZU	Histidine kinase
Varpa_3579	ENOG4105CD8	aminopeptidase N
Varpa_3580	ENOG4105DJB	Major Facilitator Superfamily
Varpa_3581	ENOG4108Z9W	Outer membrane porin
Varpa_3582	ENOG4105E3J	oxidoreductase
Varpa_3588	ENOG4105C26	Dehydrogenase
Varpa_3589	ENOG4108Q27	Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate (By similarity)
Varpa_3590	ENOG4105C7K	acetolactate synthase
Varpa_3591	ENOG4105CHR	reductase
Varpa_3592	ENOG4107HP6	Transcriptional regulator
Varpa_3597	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
Varpa_3598	ENOG4108JZF	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
Varpa_3599	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
Varpa_3601	ENOG4105DT1	RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate
Varpa_3603	ENOG4105CJE	phosphoribulokinase (EC 2.7.1.19)
Varpa_3604	ENOG4105EHU	Circadian clock protein KaiC
Varpa_3605	ENOG4105BZU	Histidine kinase
Varpa_3610	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
Varpa_3611	ENOG4108IEG	Formate dehydrogenase Alpha subunit
Varpa_3618	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
Varpa_3619	ENOG4105QAX	Iron-sulfur
Varpa_3623	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
Varpa_3624	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
Varpa_3627	ENOG4105K70	DNA-binding protein
Varpa_3639	ENOG4108ZX5	transcriptional regulator
Varpa_3641	ENOG4105CEY	Amp-dependent synthetase and ligase
Varpa_3644	ENOG4105C7F	AcnD-accessory protein PrpF
Varpa_3645	ENOG4108I0Z	Aconitate hydratase
Varpa_3646	ENOG4105BZN	citrate synthase
Varpa_3653	ENOG41060WC	Enoyl-CoA hydratase
Varpa_3658	ENOG4105K6S	Short-chain dehydrogenase reductase Sdr
Varpa_3664	ENOG4105CCT	upf0313 protein
Varpa_3665	ENOG410645S	MarR family Transcriptional regulator
Varpa_3667	ENOG4107GD3	Catalyzes the conversion of acetoacetate to acetone and carbon dioxide (By similarity)
Varpa_3671	ENOG4107S2Z	UPF0761 membrane protein
Varpa_3673	ENOG4105CAH	Chromate
Varpa_3674	ENOG4105CPC	Aldo Keto reductase
Varpa_3675	ENOG4105NI3	Protein of unknown function (DUF3237)
Varpa_3676	ENOG4108Z7F	N-acetyltransferase
Varpa_3680	ENOG4105C2N	RNA methyltransferase TrmH family group 3
Varpa_3683	ENOG4108I0Y	(ABC) transporter
Varpa_3684	ENOG4108UJV	acyl-CoA thioesterase i
Varpa_3687	ENOG4105C28	cystathionine
Varpa_3692	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
Varpa_3693	ENOG4105C49	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity)
Varpa_3695	ENOG4105EPW	hflc protein
Varpa_3696	ENOG4107QJR	hflk protein
Varpa_3697	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
Varpa_3698	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
Varpa_3699	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
Varpa_3702	ENOG4105CUT	histidyl-tRNA synthetase
Varpa_3703	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
Varpa_3706	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
Varpa_3707	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
Varpa_3708	ENOG4105FE9	pseudouridine synthase
Varpa_3709	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
Varpa_3710	ENOG4105C34	Pseudouridine synthase
Varpa_3712	ENOG4105DVT	helicase
Varpa_3716	ENOG4105D6Z	AFG1 family ATPase
Varpa_3717	ENOG4107QN2	dihydrolipoyl dehydrogenase
Varpa_3718	ENOG4105C7S	Dehydrogenase
Varpa_3719	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
Varpa_3720	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
Varpa_3725	ENOG4105D8V	Glucose sorbosone dehydrogenase
Varpa_3726	ENOG4105K4H	Nlp p60 protein
Varpa_3727	ENOG4107QN2	dihydrolipoyl dehydrogenase
Varpa_3728	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
Varpa_3729	ENOG4107QSN	dihydrolipoamide acetyltransferase
Varpa_3730	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
Varpa_3731	ENOG4105BZU	Histidine kinase
Varpa_3732	ENOG4108ZXC	Two component transcriptional regulator, luxr family
Varpa_3733	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
Varpa_3734	ENOG4105DGW	oligopeptidase A
Varpa_3736	ENOG4105E66	phosphoriboisomerase A
Varpa_3737	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
Varpa_3740	ENOG4105D5U	fad dependent oxidoreductase
Varpa_3743	ENOG4107RZZ	dna polymerase iii epsilon subunit
Varpa_3744	ENOG4108ZIT	Ferredoxin, 2FE-2S
Varpa_3745	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
Varpa_3746	ENOG4108SWN	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA (By similarity)
Varpa_3748	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
Varpa_3749	ENOG4105C3J	Cysteine desulfurase
Varpa_3750	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
Varpa_3751	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
Varpa_3752	ENOG4105CGF	Aromatic amino acid aminotransferase
Varpa_3754	ENOG4108R3D	Electron transport complex
Varpa_3756	ENOG4105FDR	Membrane
Varpa_3759	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
Varpa_3760	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
Varpa_3761	ENOG4107QX3	carboxylase
Varpa_3762	ENOG4105DJT	lAO AO transport system ATPase
Varpa_3766	ENOG4105DRR	Transcriptional regulator, GntR family
Varpa_3768	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
Varpa_3769	ENOG4105BZU	Histidine kinase
Varpa_3774	ENOG4105K56	Transcriptional regulator
Varpa_3776	ENOG4105F6U	Short-chain dehydrogenase reductase Sdr
Varpa_3777	ENOG4105M4P	Tetr family transcriptional regulator
Varpa_3779	ENOG4105C7K	acetolactate synthase
Varpa_3780	ENOG4105EW9	transcriptional regulator AsnC family
Varpa_3789	ENOG4105WH1	Two component transcriptional regulator luxr family
Varpa_3798	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
Varpa_3802	ENOG4105BZU	Histidine kinase
Varpa_3805	ENOG4105C32	Amino acid ABC transporter (Permease)
Varpa_3807	ENOG4105C0Z	ABC transporter
Varpa_3808	ENOG4108IV0	ABC, transporter
Varpa_3810	ENOG4105C26	Dehydrogenase
Varpa_3811	ENOG4108R85	Short chain dehydrogenase
Varpa_3812	ENOG4105ERH	Fumarylacetoacetate hydrolase
Varpa_3814	ENOG4105F1J	Homogentisate 1,2-dioxygenase
Varpa_3816	ENOG4108YYH	Nadph-dependent fmn reductase
Varpa_3819	ENOG4108MXQ	glutathione-regulated potassium-efflux system ancillary protein KefF
Varpa_3824	ENOG4105F04	LysR family Transcriptional regulator
Varpa_3826	ENOG4105ETE	Transcriptional regulator (LacI family
Varpa_3828	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
Varpa_3829	ENOG4105KVH	Transcriptional regulator
Varpa_3838	ENOG4107RYT	DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair (By similarity)
Varpa_3847	ENOG4105CTK	cobaltochelatase, cobn subunit
Varpa_3848	ENOG4107QRP	cobalamin biosynthesis protein CobW
Varpa_3851	ENOG4105E0K	tonB-dependent siderophore receptor
Varpa_3854	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
Varpa_3855	ENOG4105CK2	sodium dicarboxylate symporter
Varpa_3856	ENOG4105CHR	reductase
Varpa_3858	ENOG4105CEV	competence damage-inducible protein
Varpa_3861	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
Varpa_3862	ENOG4108M9J	MaoC like domain protein
Varpa_3864	ENOG4107653	Transcriptional regulator
Varpa_3865	ENOG4105CYM	Glutathione S-transferase
Varpa_3867	ENOG4105CHU	acetyl-coa acetyltransferase
Varpa_3868	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
Varpa_3870	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
Varpa_3875	ENOG4108RH0	Crea protein
Varpa_3876	ENOG4108K5P	(LipO)protein
Varpa_3877	ENOG4107RZC	phospholipase d
Varpa_3880	ENOG4105CF1	Alkylated DNA repair protein
Varpa_3881	ENOG4105BZ1	(ABC) transporter
Varpa_3882	ENOG4105ETE	Transcriptional regulator (LacI family
Varpa_3883	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
Varpa_3884	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
Varpa_3886	ENOG4105DT1	RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate
Varpa_3895	ENOG4105UCG	Domain of unknown function (DUF333)
Varpa_3903	ENOG4105E39	Enoyl-CoA hydratase
Varpa_3904	ENOG4105CD5	CoA-binding domain protein
Varpa_3905	ENOG4105C5I	Dehydrogenase
Varpa_3909	ENOG4108MVM	Transposase
Varpa_3910	ENOG4108ZQS	transposase
Varpa_3917	ENOG4108MVM	Transposase
Varpa_3919	ENOG4105J1P	transposase, IS3 IS911 family protein
Varpa_3922	ENOG4108MVM	Transposase
Varpa_3931	ENOG4105D5K	Hemolysin activator protein
Varpa_3933	ENOG4105CKT	filamentous hemagglutinin
Varpa_3938	ENOG4105J1P	transposase, IS3 IS911 family protein
Varpa_3942	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
Varpa_3943	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
Varpa_3944	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
Varpa_3945	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
Varpa_3946	ENOG4105VJV	50s ribosomal protein L35
Varpa_3947	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
Varpa_3948	ENOG4105C22	threonyL-tRNA synthetase
Varpa_3949	ENOG4108I9X	Isocitrate lyase
Varpa_3956	ENOG4108W9H	Tetr family transcriptional regulator
Varpa_3958	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
Varpa_3959	ENOG4107XKF	NMT1 THI5 Like Domain Protein
Varpa_3965	ENOG4105T0Z	Conserved Protein
Varpa_3966	ENOG410908U	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
Varpa_3970	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
Varpa_3971	ENOG4105K8N	protein family UPF0079, ATPase
Varpa_3972	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
Varpa_3974	ENOG4105DQR	SNARE associated Golgi
Varpa_3976	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
Varpa_3980	ENOG4105W2Z	cytochrome C, class I
Varpa_3981	ENOG4105CF7	AraC family transcriptional regulator
Varpa_3982	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
Varpa_3983	ENOG4108I0Y	(ABC) transporter
Varpa_3985	ENOG4105JXH	GntR family transcriptional regulator
Varpa_3988	ENOG4105GRZ	Ycii-related protein
Varpa_3989	ENOG4105CHP	RNA polymerase
Varpa_3990	ENOG41066YJ	Beta-lactamase
Varpa_3998	ENOG4105C32	Amino acid ABC transporter (Permease)
Varpa_4001	ENOG4108IV0	ABC, transporter
Varpa_4002	ENOG4105C0Z	ABC transporter
Varpa_4004	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
Varpa_4005	ENOG4105CW7	secretion protein, HlyD family
Varpa_4006	ENOG4105ETP	RND efflux system, outer membrane lipoprotein
Varpa_4007	ENOG4108T3F	Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes
Varpa_4008	ENOG4105BZ1	(ABC) transporter
Varpa_4010	ENOG4108YZ4	nudix hydrolase
Varpa_4012	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
Varpa_4013	ENOG4105C8S	subunit m
Varpa_4015	ENOG4105M5H	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
Varpa_4016	ENOG4105DF2	NADH dehydrogenase subunit j
Varpa_4017	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
Varpa_4018	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
Varpa_4019	ENOG4108IEH	NADH dehydrogenase subunit g
Varpa_4020	ENOG4107QIZ	NADH dehydrogenase
Varpa_4022	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
Varpa_4023	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
Varpa_4024	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
Varpa_4025	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
Varpa_4026	ENOG4107EJC	Preprotein translocase subunit SecG
Varpa_4027	ENOG4105CP7	Triose-phosphate isomerase
Varpa_4029	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
Varpa_4030	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
Varpa_4031	ENOG4108PCN	EamA-like transporter family
Varpa_4032	ENOG4105CHM	Aminotransferase
Varpa_4033	ENOG4105ES9	amino acid
Varpa_4035	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
Varpa_4037	ENOG4105I5W	Transporter
Varpa_4039	ENOG4105D7T	ABC transporter
Varpa_4043	ENOG4108IFG	nitrite reductase, (NAD(P)H)
Varpa_4045	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
Varpa_4047	ENOG4108I0Q	anthranilate phosphoribosyltransferase
Varpa_4048	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
Varpa_4050	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
Varpa_4052	ENOG4105F38	ABC transporter, permease
Varpa_4053	ENOG4105EG2	ABC transporter, permease
Varpa_4055	ENOG4108UY0	(LipO)protein
Varpa_4056	ENOG4105CBX	hi0933 family
Varpa_4057	ENOG4105VCC	30S ribosomal protein S21
Varpa_4059	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
Varpa_4063	ENOG4105C09	Bile acid
Varpa_4064	ENOG4105H3G	oxidoreductase
Varpa_4065	ENOG4107FW0	short-chain dehydrogenase reductase
Varpa_4066	ENOG4105CPQ	Dehydrogenase
Varpa_4067	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
Varpa_4072	ENOG4107XVH	Transcriptional regulator
Varpa_4073	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
Varpa_4074	ENOG4105N42	UPF0307 protein
Varpa_4075	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
Varpa_4095	ENOG4105W1Y	Transcriptional regulator
Varpa_4098	ENOG4105EXG	Transcriptional regulator
Varpa_4100	ENOG4105D7W	serine acetyltransferase
Varpa_4102	ENOG4105ECY	inositol monophosphatase
Varpa_4107	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
Varpa_4108	ENOG4105CF7	AraC family transcriptional regulator
Varpa_4111	ENOG4108RPX	mosc domain containing protein
Varpa_4116	ENOG4105JN3	extra-cytoplasmic solute receptor family protein
Varpa_4117	ENOG4105ENH	Sulfatase
Varpa_4122	ENOG4105DEF	Extracellular solute-binding protein, family 5
Varpa_4123	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
Varpa_4124	ENOG4108EU3	peptide transport system, permease
Varpa_4125	ENOG4105C3U	ABC transporter
Varpa_4130	ENOG4105NTW	Transcriptional regulator
Varpa_4131	ENOG4105Q26	Siderophore-interacting protein
Varpa_4132	ENOG4105D7N	magnesium and cobalt transport protein CorA
Varpa_4134	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
Varpa_4138	ENOG4105CHP	RNA polymerase
Varpa_4139	ENOG4105GRZ	Ycii-related protein
Varpa_4140	ENOG4105DTD	Dehydrogenase
Varpa_4143	ENOG4105ENE	Histidine kinase
Varpa_4144	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
Varpa_4149	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
Varpa_4150	ENOG4105BZS	acriflavin resistance protein
Varpa_4152	ENOG4105BZS	acriflavin resistance protein
Varpa_4157	ENOG4108HRK	Histidine kinase
Varpa_4158	ENOG4108VAC	response regulator
Varpa_4160	ENOG4105CX6	glutaminyL-tRNA synthetase
Varpa_4164	ENOG4108R99	pseudouridine synthase
Varpa_4179	ENOG4105CIG	ABC transporter
Varpa_4180	ENOG4105YK5	50S ribosomal protein L36
Varpa_4183	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
Varpa_4185	ENOG4105C2X	Arabinose 5-phosphate isomerase
Varpa_4187	ENOG4105VUF	Transcriptional regulator
Varpa_4189	ENOG4105KF3	Short-chain dehydrogenase reductase Sdr
Varpa_4190	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
Varpa_4191	ENOG4105D9M	gamma-glutamylcysteine synthetase
Varpa_4193	ENOG4106CJB	Phospholipase Carboxylesterase
Varpa_4196	ENOG4105CKI	cobalamin synthesis protein
Varpa_4197	ENOG4105CHR	reductase
Varpa_4201	ENOG4105CSH	Transporter
Varpa_4208	ENOG4105CKW	Inner membrane protein yedI
Varpa_4212	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
Varpa_4215	ENOG4105D3G	Pseudouridine synthase
Varpa_4216	ENOG4107YZX	Universal stress protein
Varpa_4219	ENOG41067HS	methyltransferase
Varpa_4220	ENOG4105E46	N-alpha,N-alpha,N-alpha-trimethyl-L-histidine metabolic process
Varpa_4221	ENOG4105CEP	NADH dehydrogenase
Varpa_4225	ENOG4105CEY	Amp-dependent synthetase and ligase
Varpa_4226	ENOG4108Z9K	Osmotically inducible protein
Varpa_4230	ENOG4106517	Short-chain dehydrogenase reductase Sdr
Varpa_4232	ENOG4105CSP	Major Facilitator Superfamily
Varpa_4234	ENOG4107RP9	extracellular solute-binding protein, family 3
Varpa_4235	ENOG4105DRP	amino acid AbC transporter
Varpa_4236	ENOG4105E5Q	amino acid AbC transporter
Varpa_4241	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
Varpa_4245	ENOG4107R16	Multicopper oxidase
Varpa_4249	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
Varpa_4250	ENOG4105KXX	peptidase s58 dmpa
Varpa_4253	ENOG4105VUF	Transcriptional regulator
Varpa_4255	ENOG4105C5H	ABC transporter
Varpa_4256	ENOG4105C1J	atp-dependent rna helicase
Varpa_4260	ENOG4105D56	permease protein
Varpa_4262	ENOG4107EJG	GntR family transcriptional regulator
Varpa_4263	ENOG4105C01	Dihydroxy-acid dehydratase
Varpa_4264	ENOG4105EI3	2-dehydro-3-deoxygalactonokinase EC 2.7.1.58
Varpa_4265	ENOG4108RTU	Aldolase
Varpa_4266	ENOG4107R0P	L-ribulose-5-phosphate 4-epimerase
Varpa_4273	ENOG4105BZU	Histidine kinase
Varpa_4274	ENOG4107R6F	Alpha Beta Hydrolase Fold protein
Varpa_4277	ENOG4108UCS	ABC, transporter
Varpa_4279	ENOG4108UYE	Lactoylglutathione lyase
Varpa_4282	ENOG4108UHU	Aldolase
Varpa_4283	ENOG4105C01	Dihydroxy-acid dehydratase
Varpa_4288	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
Varpa_4289	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
Varpa_4292	ENOG4105UGU	tonB-dependent Receptor
Varpa_4294	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
Varpa_4295	ENOG4105YA8	Transcriptional regulator
Varpa_4296	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
Varpa_4297	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
Varpa_4300	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
Varpa_4301	ENOG4107QKV	phosphomannomutase
Varpa_4304	ENOG4107RT3	EamA-like transporter family
Varpa_4307	ENOG4105CEY	Amp-dependent synthetase and ligase
Varpa_4310	ENOG4105CQB	FAD linked oxidase domain protein
Varpa_4313	ENOG4105CYM	Glutathione S-transferase
Varpa_4314	ENOG4107SQI	penicillin amidase
Varpa_4316	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
Varpa_4317	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
Varpa_4318	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
Varpa_4319	ENOG4105F1Y	L-lysine 6-monooxygenase (NADPH)
Varpa_4320	ENOG4105IBP	Cyclic peptide transporter
Varpa_4322	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
Varpa_4323	ENOG4105E0K	tonB-dependent siderophore receptor
Varpa_4335	ENOG4107T31	5'-nucleotidase
Varpa_4337	ENOG4105F04	LysR family Transcriptional regulator
Varpa_4340	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
Varpa_4341	ENOG4105DEF	Extracellular solute-binding protein, family 5
Varpa_4342	ENOG4108JQ7	(ABC) transporter
Varpa_4343	ENOG4105C3U	ABC transporter
Varpa_4344	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
Varpa_4346	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
Varpa_4348	ENOG4105C1G	acyl-Coa dehydrogenase
Varpa_4349	ENOG4105CEY	Amp-dependent synthetase and ligase
Varpa_4351	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
Varpa_4352	ENOG4105C28	cystathionine
Varpa_4353	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
Varpa_4356	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
Varpa_4357	ENOG4105KUZ	arsenate reductase
Varpa_4359	ENOG4105NBK	UPF0345 protein
Varpa_4360	ENOG4105CDH	Citrulline--aspartate ligase
Varpa_4362	ENOG4105D4A	Cell wall formation (By similarity)
Varpa_4363	ENOG4108VPT	UPF0234 protein
Varpa_4365	ENOG4105M4H	endoribonuclease L-psp
Varpa_4366	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
Varpa_4367	ENOG4108Z66	YbaK ebsC protein
Varpa_4368	ENOG4105CPC	Aldo Keto reductase
Varpa_4369	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
Varpa_4374	ENOG4105D01	(LipO)protein
Varpa_4375	ENOG4108UMI	ABC transporter, permease
Varpa_4376	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
Varpa_4377	ENOG4105D01	(LipO)protein
Varpa_4379	ENOG4107VXZ	Hydrolase
Varpa_4380	ENOG4105CD8	aminopeptidase N
Varpa_4381	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
Varpa_4382	ENOG4108R4U	Hnh endonuclease
Varpa_4386	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
Varpa_4398	ENOG4108KDI	dmso reductase anchor subunit
Varpa_4399	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
Varpa_4400	ENOG4105DB1	molybdopterin oxidoreductase
Varpa_4401	ENOG4105DUM	transcriptional regulator, lysR family
Varpa_4402	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
Varpa_4404	ENOG4108FUF	Transcriptional regulator, IclR family
Varpa_4409	ENOG4108EKI	Dehydrogenase
Varpa_4410	ENOG4105CEY	Amp-dependent synthetase and ligase
Varpa_4419	ENOG4108FUF	Transcriptional regulator, IclR family
Varpa_4420	ENOG4105CZ6	Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine (By similarity)
Varpa_4426	ENOG4105EXX	Deoxyribodipyrimidine photolyase-related protein
Varpa_4429	ENOG4105CR8	Transcriptional regulator
Varpa_4430	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
Varpa_4431	ENOG4108IY8	ABC, transporter
Varpa_4432	ENOG4106FTQ	Taurine ABC transporter, periplasmic
Varpa_4434	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
Varpa_4439	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
Varpa_4441	ENOG4108JQ7	(ABC) transporter
Varpa_4442	ENOG4105CI2	imidazolone-5-propionate hydrolase
Varpa_4443	ENOG4107QRP	cobalamin biosynthesis protein CobW
Varpa_4456	ENOG4107RZC	phospholipase d
Varpa_4463	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
Varpa_4464	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
Varpa_4467	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
Varpa_4469	ENOG41068WN	
Varpa_4475	ENOG4105D4R	Catalyzes the desulfonation of aliphatic sulfonates (By similarity)
Varpa_4477	ENOG4105FDT	acyl-CoA dehydrogenase
Varpa_4478	ENOG4105GVF	(ABC) transporter
Varpa_4479	ENOG4108T2C	cysteine dioxygenase type I
Varpa_4482	ENOG4105C1J	atp-dependent rna helicase
Varpa_4483	ENOG4105CGZ	zinc metallopeptidase
Varpa_4484	ENOG4105DHP	deoxycytidine triphosphate deaminase
Varpa_4485	ENOG4107QUY	Guanine deaminase
Varpa_4487	ENOG4105EMU	Dehydrogenase
Varpa_4489	ENOG4105C6X	Major Facilitator
Varpa_4490	ENOG4107SQI	penicillin amidase
Varpa_4491	ENOG41063TF	transcriptional regulator (AraC
Varpa_4493	ENOG4107RDB	Major Facilitator
Varpa_4494	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
Varpa_4498	ENOG4105GAK	amidohydrolase 2
Varpa_4501	ENOG4105CI0	Citrate lyase
Varpa_4503	ENOG4105BZU	Histidine kinase
Varpa_4504	ENOG4107QHF	type ii secretion system protein e
Varpa_4505	ENOG4105BZU	Histidine kinase
Varpa_4509	ENOG4105UIB	(ABC) transporter
Varpa_4510	ENOG4108JQ9	ABC transporter
Varpa_4511	ENOG4105C7N	Xanthine uracil vitamin C permease
Varpa_4513	ENOG4105C7W	Xanthine dehydrogenase
Varpa_4519	ENOG4105CEY	Amp-dependent synthetase and ligase
Varpa_4521	ENOG4105DKB	L-sorbosone dehydrogenase
Varpa_4527	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
Varpa_4529	ENOG4105KJF	protein tyrosine phosphatase
Varpa_4539	ENOG4107YCY	Transcriptional regulator
Varpa_4542	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
Varpa_4548	ENOG4105FBN	Acid phosphatase
Varpa_4559	ENOG4105EW8	cytosine purines, uracil, thiamine, allantoin permease
Varpa_4562	ENOG4105C2W	permease
Varpa_4563	ENOG4105CV8	reductase
Varpa_4565	ENOG4105CK2	sodium dicarboxylate symporter
Varpa_4567	ENOG4105F4G	Membrane
Varpa_4570	ENOG4105CC0	LysR family Transcriptional regulator
Varpa_4571	ENOG41060W2	glyoxylate carboligase
Varpa_4572	ENOG4105QG4	Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity)
Varpa_4573	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
Varpa_4575	ENOG4105C6K	Malic enzyme
Varpa_4582	ENOG4105CS6	Rhs element vgr protein
Varpa_4584	ENOG4105D7T	ABC transporter
Varpa_4585	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
Varpa_4595	ENOG4105EW9	transcriptional regulator AsnC family
Varpa_4596	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
Varpa_4598	ENOG4105D2X	ABC transporter substrate-binding protein
Varpa_4599	ENOG4108Z6B	deaminase
Varpa_4600	ENOG4108M9X	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
Varpa_4607	ENOG4107NQ8	LysR family Transcriptional regulator
Varpa_4611	ENOG4105C28	cystathionine
Varpa_4614	ENOG4107S4Y	M20 DapE family protein YgeY
Varpa_4616	ENOG4105J1P	transposase, IS3 IS911 family protein
Varpa_4617	ENOG4105VCD	cytoplasmic protein
Varpa_4618	ENOG4105D22	carbon starvation protein
Varpa_4619	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
Varpa_4620	ENOG4105K4H	Nlp p60 protein
Varpa_4622	ENOG4108WFR	AraC Family Transcriptional Regulator
Varpa_4627	ENOG4108IXY	short-chain dehydrogenase reductase
Varpa_4629	ENOG4105JQN	Transcriptional regulator
Varpa_4631	ENOG4108TY5	Exhibits lactonase activity. Acts in cells with perturbed membrane integrity and is possibly related to the membrane homeostasis
Varpa_4634	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
Varpa_4638	ENOG4105EQ0	Major Facilitator superfamily
Varpa_4642	ENOG4105BZS	acriflavin resistance protein
Varpa_4644	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
Varpa_4645	ENOG4105CPC	Aldo Keto reductase
Varpa_4646	ENOG4105F27	Major Facilitator
Varpa_4647	ENOG4108IV0	ABC, transporter
Varpa_4648	ENOG4105C0Z	ABC transporter
Varpa_4650	ENOG4105C32	Amino acid ABC transporter (Permease)
Varpa_4651	ENOG4107TSX	ABC branched chain amino acid family transporter periplasmic ligand binding protein
Varpa_4656	ENOG4105CSR	polyphosphate kinase 2
Varpa_4657	ENOG4105CJ3	phosphate transporter
Varpa_4659	ENOG4105DB7	PHP domain protein
Varpa_4661	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
Varpa_4662	ENOG4108Z4T	Peptidase M50
Varpa_4663	ENOG4105C31	Tryptophanyl-tRNA synthetase
Varpa_4664	ENOG4105WH1	Two component transcriptional regulator luxr family
Varpa_4667	ENOG41086DT	Membrane protein of unknown function
Varpa_4671	ENOG4105E3R	(LipO)protein
Varpa_4678	ENOG4105D3Q	Sugar transferase
Varpa_4681	ENOG4105CMR	udp-glucose 4-epimerase
Varpa_4682	ENOG4107XU6	Glycosyl transferase (Group 1
Varpa_4686	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
Varpa_4687	ENOG4105J5G	Transferase hexapeptide repeat containing protein
Varpa_4688	ENOG4107R5Z	Oxidoreductase domain protein
Varpa_4689	ENOG4107QQG	Dehydrogenase
Varpa_4691	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
Varpa_4692	ENOG4105C7B	Threonine dehydratase
Varpa_4693	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
Varpa_4694	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
Varpa_4695	ENOG4105W5Q	DNA repair protein (RadC
Varpa_4699	ENOG4105RKW	reductase (By
Varpa_4700	ENOG4106PMH	Extracellular solute-binding protein family 3
Varpa_4701	ENOG4105EAD	ABC transporter
Varpa_4702	ENOG4105DRP	amino acid AbC transporter
Varpa_4705	ENOG4105CF7	AraC family transcriptional regulator
Varpa_4706	ENOG4107XKX	isoquinoline 1-oxidoreductase, alpha subunit
Varpa_4707	ENOG4105DIP	Molybdopterin dehydrogenase FAD-binding
Varpa_4708	ENOG4105C7W	Xanthine dehydrogenase
Varpa_4709	ENOG4107VXZ	Hydrolase
Varpa_4710	ENOG4105CSH	Transporter
Varpa_4711	ENOG4105E2S	oxidase) subunit II
Varpa_4712	ENOG4105BZ9	Cytochrome C oxidase, subunit I
Varpa_4713	ENOG4105CCU	oxidase (Subunit III)
Varpa_4714	ENOG41090KH	cytochrome o ubiquinol oxidase (subunit iv)
Varpa_4716	ENOG4105TX3	Histidine kinase
Varpa_4717	ENOG4108UYB	regulatoR
Varpa_4719	ENOG41069P5	Protein slyX homolog
Varpa_4720	ENOG4105C57	major facilitator superfamily
Varpa_4721	ENOG4105CC0	LysR family Transcriptional regulator
Varpa_4725	ENOG4105CV6	ABC transporter, permease
Varpa_4727	ENOG4105EHI	Phosphonate ABC transporter, periplasmic
Varpa_4728	ENOG4105D5T	phosphonate abc transporter
Varpa_4729	ENOG4105S7S	phosphonate abc transporter
Varpa_4731	ENOG4105CR7	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA (By similarity)
Varpa_4732	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
Varpa_4734	ENOG4107QKC	Oxidoreductase alpha (molybdopterin) subunit
Varpa_4736	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
Varpa_4737	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
Varpa_4738	ENOG4105E0C	molybdate abc transporter
Varpa_4740	ENOG4105F4R	Transcriptional regulator mode
Varpa_4741	ENOG4105FCD	Major Facilitator
Varpa_4742	ENOG4105C5Q	Transcriptional regulator
Varpa_4746	ENOG4107RCH	Diaminopropionate ammonia-lyase
Varpa_4747	ENOG4105CH2	amidohydrolase
Varpa_4748	ENOG4105EW9	transcriptional regulator AsnC family
Varpa_4750	ENOG4108YXG	UPF0502 protein
Varpa_4751	ENOG4108T58	Mg2 transport protein CorA
Varpa_4752	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
Varpa_4753	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
Varpa_4755	ENOG4105CHH	sulfate transporter
Varpa_4759	ENOG4108IYU	L-aspartate oxidase
Varpa_4760	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
Varpa_4761	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
Varpa_4762	ENOG4107RJX	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
Varpa_4764	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
Varpa_4765	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
Varpa_4766	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
Varpa_4767	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
Varpa_4769	ENOG4105WZW	rhodanese family
Varpa_4770	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
Varpa_4771	ENOG4105CN1	protease
Varpa_4772	ENOG4105D06	uba thif-type nad fad binding protein
Varpa_4773	ENOG41066T0	asmA family
Varpa_4775	ENOG4105WH1	Two component transcriptional regulator luxr family
Varpa_4776	ENOG4105BZU	Histidine kinase
Varpa_4782	ENOG4105K3G	Periplasmic Protein
Varpa_4783	ENOG41067RQ	csbd family
Varpa_4785	ENOG41090TI	Catalyzes the excretion of spermidine (By similarity)
Varpa_4787	ENOG4105EUJ	GTP cyclohydrolase i
Varpa_4789	ENOG4108TIT	dATP pyrophosphohydrolase
Varpa_4792	ENOG4105C9M	aspartyl-trna synthetase
Varpa_4795	ENOG4108IA2	Sodium pantothenate symporter
Varpa_4796	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
Varpa_4799	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
Varpa_4804	ENOG4108JQ1	Dehydrogenase
Varpa_4806	ENOG4105E4X	binding-protein-dependent transport systems inner membrane Component
Varpa_4808	ENOG4108IJ9	(ABC) transporter
Varpa_4809	ENOG4107T6V	glycerophosphoryl diester phosphodiesterase
Varpa_4810	ENOG4105EGS	Mechanosensitive ion channel
Varpa_4811	ENOG4108YXU	transcriptional regulator AsnC family
Varpa_4813	ENOG4105C7J	ABC transporter, permease
Varpa_4814	ENOG4105D5T	phosphonate abc transporter
Varpa_4817	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
Varpa_4818	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
Varpa_4819	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
Varpa_4822	ENOG4105C37	(CBS) domain
Varpa_4823	ENOG4105E4C	Lytic transglycosylase catalytic
Varpa_4824	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
Varpa_4825	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
Varpa_4827	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
Varpa_4828	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
Varpa_4829	ENOG4105K46	50S ribosomal protein l27
Varpa_4830	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
Varpa_4831	ENOG4105EAH	synthase
Varpa_4832	ENOG4107QHF	type ii secretion system protein e
Varpa_4836	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
Varpa_4838	ENOG4105DHA	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity (By similarity)
Varpa_4839	ENOG41067SF	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity)
Varpa_4840	ENOG4105EXC	Acyl-transferase
Varpa_4841	ENOG4105M6F	mutator MutT protein
Varpa_4843	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
Varpa_4844	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
Varpa_4847	ENOG4108IYI	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine (By similarity)
Varpa_4848	ENOG4108SGR	YheO domain-containing protein
Varpa_4850	ENOG4107RH1	pyridoxal-5'-phosphate-dependent protein beta subunit
Varpa_4851	ENOG4105RQF	LysR family Transcriptional regulator
Varpa_4853	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
Varpa_4854	ENOG4105BZU	Histidine kinase
Varpa_4855	ENOG4108YZ9	Urea amidohydrolase subunit gamma
Varpa_4857	ENOG4105KI2	Urea amidohydrolase subunit beta
Varpa_4858	ENOG4105CQM	Urea amidohydrolase subunit alpha
Varpa_4861	ENOG4105MMR	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly (By similarity)
Varpa_4862	ENOG4108WKG	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
Varpa_4863	ENOG4105E8T	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG (By similarity)
Varpa_4866	ENOG4108Z9W	Outer membrane porin
Varpa_4868	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
Varpa_4869	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
Varpa_4873	ENOG4105EB3	Histidine kinase
Varpa_4874	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
Varpa_4875	ENOG4105EM2	membrane
Varpa_4877	ENOG4108XRP	Membrane
Varpa_4878	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
Varpa_4879	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
Varpa_4880	ENOG4105BZS	acriflavin resistance protein
Varpa_4883	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
Varpa_4884	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
Varpa_4885	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
Varpa_4887	ENOG4105ETT	transcriptional Regulator, LysR family
Varpa_4890	ENOG41064T2	transcriptional regulator, lysR family
Varpa_4892	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
Varpa_4894	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
Varpa_4898	ENOG4105CMG	Carbohydrate kinase
Varpa_4899	ENOG4105C6Z	Gluconate
Varpa_4900	ENOG4105DIQ	Transcriptional regulator
Varpa_4904	ENOG4105CHR	reductase
Varpa_4906	ENOG4105EE5	Membrane protein terC
Varpa_4919	ENOG41062A4	Transcriptional regulator
Varpa_4920	ENOG4107RP9	extracellular solute-binding protein, family 3
Varpa_4924	ENOG4105C1G	acyl-Coa dehydrogenase
Varpa_4925	ENOG4105IH7	synthase
Varpa_4931	ENOG4105E4G	Type IV pilus
Varpa_4938	ENOG4107S4Z	Activates expression of the rhaBAD and rhaT operons (By similarity)
Varpa_4949	ENOG41088CQ	domain protein
Varpa_4950	ENOG4105EXG	Transcriptional regulator
Varpa_4952	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
Varpa_4953	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
Varpa_4955	ENOG4105CSA	Coproporphyrinogen iii oxidase
Varpa_4956	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
Varpa_4960	ENOG4105DSJ	YicC domain protein
Varpa_4961	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
Varpa_4962	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
Varpa_4963	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
Varpa_4964	ENOG4108RRZ	Transcription elongation factor GreB
Varpa_4966	ENOG4105EE5	Membrane protein terC
Varpa_4967	ENOG4105CIF	Ornithine Cyclodeaminase
Varpa_4971	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
Varpa_4973	ENOG4108JIR	Flagellum-specific ATP synthase
Varpa_4976	ENOG4107Y59	type iii secretion
Varpa_4981	ENOG4105K44	type iii secretion
Varpa_4982	ENOG41083GP	type iii secretion
Varpa_4988	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
Varpa_4989	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
Varpa_4990	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
Varpa_4991	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
Varpa_4992	ENOG4105CEN	a g-specific adenine glycosylase
Varpa_4993	ENOG410890F	Dynamin family
Varpa_4994	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
Varpa_4997	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
Varpa_4998	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
Varpa_4999	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
Varpa_5000	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
Varpa_5002	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
Varpa_5004	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
Varpa_5006	ENOG4108JQ7	(ABC) transporter
Varpa_5007	ENOG4105DEF	Extracellular solute-binding protein, family 5
Varpa_5008	ENOG4105DEF	Extracellular solute-binding protein, family 5
Varpa_5009	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
Varpa_5011	ENOG4105F04	LysR family Transcriptional regulator
Varpa_5016	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
Varpa_5017	ENOG4108KN7	Removes 5-oxoproline from various penultimate amino acid residues except L-proline (By similarity)
Varpa_5018	ENOG4105E7W	lamb ycsf family protein
Varpa_5019	ENOG4107R7A	Allophanate hydrolase subunit 2
Varpa_5020	ENOG4105P4J	Allophanate hydrolase, subunit 1
Varpa_5021	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
Varpa_5022	ENOG4106H78	methyltransferase
Varpa_5028	ENOG4105BZU	Histidine kinase
Varpa_5029	ENOG4105WH1	Two component transcriptional regulator luxr family
Varpa_5033	ENOG4105IJJ	transcriptional regulator, crp fnr family
Varpa_5041	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
Varpa_5042	ENOG4105F1N	DNA alkylation repair
Varpa_5044	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
Varpa_5049	ENOG4107QS1	Cytochrome C Oxidase, Subunit III
Varpa_5051	ENOG4105FT1	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I (By similarity)
Varpa_5053	ENOG4105BZ9	Cytochrome C oxidase, subunit I
Varpa_5054	ENOG4105CV4	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
Varpa_5056	ENOG4106T9E	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
Varpa_5058	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
Varpa_5062	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
Varpa_5063	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
Varpa_5065	ENOG4105E9F	Enoyl-CoA hydratase
Varpa_5068	ENOG4105JN3	extra-cytoplasmic solute receptor family protein
Varpa_5069	ENOG4105CSU	acyl-Coa dehydrogenase
Varpa_5072	ENOG4108SQ4	Glyoxalase Bleomycin resistance protein (Dioxygenase
Varpa_5075	ENOG4105KCV	RNA signal recognition particle 4.5S RNA
Varpa_5079	ENOG4105CEP	NADH dehydrogenase
Varpa_5090	ENOG4105BZ9	Cytochrome C oxidase, subunit I
Varpa_5095	ENOG4108T5G	Adenylate
Varpa_5098	ENOG4105MSY	salicylate hydroxylase
Varpa_5100	ENOG4105JN3	extra-cytoplasmic solute receptor family protein
Varpa_5102	ENOG4105CKX	Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP
Varpa_5103	ENOG410756H	nucleotidyltransferase
Varpa_5105	ENOG4105E0Y	RtcB Protein
Varpa_5107	ENOG4105CYB	regulatoR
Varpa_5110	ENOG4107XM9	(LipO)protein
Varpa_5115	ENOG4105CQ2	DNA polymerase
Varpa_5116	ENOG4105EVD	ribosomal RNA large subunit methyltransferase N
Varpa_5119	ENOG4105F4K	antigen 43
Varpa_5123	ENOG4105BZU	Histidine kinase
Varpa_5128	ENOG4108MVM	Transposase
Varpa_5129	ENOG4108ZQS	transposase
Varpa_5131	ENOG4105J1P	transposase, IS3 IS911 family protein
Varpa_5137	ENOG4105JN3	extra-cytoplasmic solute receptor family protein
Varpa_5139	ENOG4105CHU	acetyl-coa acetyltransferase
Varpa_5140	ENOG4107QNJ	CoA-transferase subunit B
Varpa_5142	ENOG4107HP6	Transcriptional regulator
Varpa_5146	ENOG4108PPB	Seems to be required for the assembly of the photosystem I complex (By similarity)
Varpa_5161	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
Varpa_5164	ENOG4108JJA	ABC, transporter
Varpa_5167	ENOG4105KCK	Peptidoglycan-associated lipoprotein
Varpa_5170	ENOG4105DDW	LysR family Transcriptional regulator
Varpa_5173	ENOG4106RE7	Cytochrome
Varpa_5174	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
Varpa_5179	ENOG4105MA0	exported protein
Varpa_5182	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
Varpa_5183	ENOG4108JB9	formate dehydrogenase
Varpa_5184	ENOG4107QIZ	NADH dehydrogenase
Varpa_5186	ENOG4105DUM	transcriptional regulator, lysR family
Varpa_5188	ENOG4105FCD	Major Facilitator
Varpa_5190	ENOG4105DUM	transcriptional regulator, lysR family
Varpa_5191	ENOG4105CA9	Pyruvate kinase
Varpa_5193	ENOG41084M5	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
Varpa_5194	ENOG4105ERH	Fumarylacetoacetate hydrolase
Varpa_5195	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
Varpa_5196	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
Varpa_5197	ENOG4107S75	HAD-superfamily hydrolase subfamily IA variant 3
Varpa_5198	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
Varpa_5199	ENOG4105BZU	Histidine kinase
Varpa_5201	ENOG4105CFN	oxalyl-CoA decarboxylase
Varpa_5209	ENOG4105VDM	plasmid maintenance system antidote protein, xre family
Varpa_5213	ENOG4105KVH	Transcriptional regulator
Varpa_5217	ENOG4105CD3	dihydroorotase
Varpa_5218	ENOG4105CXT	aspartate transcarbamylase
Varpa_5219	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
Varpa_5220	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
Varpa_5221	ENOG4108UJU	UPF0301 protein
Varpa_5222	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
Varpa_5223	ENOG4105CBS	Chea signal transduction histidine kinase
Varpa_5224	ENOG4105C8Q	Methyl-accepting chemotaxis
Varpa_5226	ENOG4105M3Z	response regulator
Varpa_5227	ENOG4108UNF	response regulator
Varpa_5228	ENOG4105VCQ	rubredoxin
Varpa_5230	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
Varpa_5232	ENOG4105DC1	bifunctional purine biosynthesis protein purh
Varpa_5234	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
Varpa_5235	ENOG4105W39	Membrane
Varpa_5237	ENOG4105C0H	protease
Varpa_5240	ENOG4105C3G	gtp-binding protein
Varpa_5241	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
Varpa_5242	ENOG4105C2J	ABC transporter
Varpa_5243	ENOG4105CNN	ABC, transporter
Varpa_5244	ENOG4105ETE	Transcriptional regulator (LacI family
Varpa_5245	ENOG4108RVA	ribokinase
Varpa_5246	ENOG4105MRB	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity)
Varpa_5248	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
Varpa_5249	ENOG4105T95	Thiol disulfide interChange protein
Varpa_5252	ENOG4105E39	Enoyl-CoA hydratase
Varpa_5261	ENOG4105CEY	Amp-dependent synthetase and ligase
Varpa_5263	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
Varpa_5266	ENOG4105CHU	acetyl-coa acetyltransferase
Varpa_5268	ENOG41061ZR	Transcriptional regulator
Varpa_5271	ENOG4105C1G	acyl-Coa dehydrogenase
Varpa_5272	ENOG410846T	CoA-transferase family III
Varpa_5278	ENOG4105CS6	Rhs element vgr protein
Varpa_5284	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
Varpa_5285	ENOG4108UMZ	Cdp-alcohol phosphatidyltransferase
Varpa_5286	ENOG4105E8V	Alpha Beta Hydrolase Fold protein
Varpa_5287	ENOG41077RS	Phosphatase
Varpa_5290	ENOG4108HPI	phosphatidate Cytidylyltransferase
Varpa_5293	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
Varpa_5294	ENOG4105C9A	Phoh family
Varpa_5295	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
Varpa_5296	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
Varpa_5300	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
Varpa_5302	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
Varpa_5303	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
Varpa_5304	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
Varpa_5305	ENOG4108UJD	30S ribosomal protein S9
Varpa_5306	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
Varpa_5308	ENOG4105D6S	protein involved in catabolism of external DNA
Varpa_5310	ENOG4105SYT	Methylenetetrahydrofolate reductase
Varpa_5311	ENOG4105DX0	Hemolysin A
Varpa_5312	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
Varpa_5319	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
Varpa_5322	ENOG4108IUW	ABC transporter
Varpa_5326	ENOG4107R3N	Filamentation induced by cAMP protein fic
Varpa_5327	ENOG4105JN3	extra-cytoplasmic solute receptor family protein
Varpa_5328	ENOG41067B5	Histone deacetylase superfamily protein
Varpa_5329	ENOG4107QWB	Ornithine cyclodeaminase
Varpa_5330	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
Varpa_5334	ENOG4105CSH	Transporter
Varpa_5338	ENOG410829K	Lysine exporter protein (Lyse ygga)
Varpa_5339	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
Varpa_5340	ENOG4105DND	Transcriptional regulator
Varpa_5346	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
Varpa_5348	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
Varpa_5351	ENOG4108K8U	Glycerol operon regulatory protein
Varpa_5352	ENOG4105JPG	D-isomer specific 2-hydroxyacid dehydrogenase
Varpa_5357	ENOG41060WC	Enoyl-CoA hydratase
Varpa_5358	ENOG4107QX3	carboxylase
Varpa_5359	ENOG4105CEY	Amp-dependent synthetase and ligase
Varpa_5360	ENOG4105C1G	acyl-Coa dehydrogenase
Varpa_5364	ENOG4105MN5	HAD-superfamily hydrolase subfamily IA variant 3
Varpa_5365	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
Varpa_5366	ENOG4105K5B	UPF0225 protein
Varpa_5367	ENOG4105BZU	Histidine kinase
Varpa_5370	ENOG4105DIN	metallophosphoesterase
Varpa_5371	ENOG4105C1G	acyl-Coa dehydrogenase
Varpa_5373	ENOG4105CHU	acetyl-coa acetyltransferase
Varpa_5374	ENOG4105VS7	Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation (By similarity)
Varpa_5375	ENOG41077A9	carbonic anhydrase
Varpa_5376	ENOG4108Z6Z	Transcriptional regulator
Varpa_5379	ENOG4105D3G	Pseudouridine synthase
Varpa_5380	ENOG4105CHR	reductase
Varpa_5381	ENOG4105C01	Dihydroxy-acid dehydratase
Varpa_5382	ENOG4105EXW	epimerase dehydratase
Varpa_5383	ENOG4108KWP	DNA-binding transcriptional regulator GlcC
Varpa_5387	ENOG4105EG2	ABC transporter, permease
Varpa_5390	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
Varpa_5393	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
Varpa_5394	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
Varpa_5395	ENOG4105CBD	Diacylglycerol kinase
Varpa_5401	ENOG4105EQ0	Major Facilitator superfamily
Varpa_5403	ENOG4105KF3	Short-chain dehydrogenase reductase Sdr
Varpa_5404	ENOG4105DE9	3-keto-5-aminohexanoate cleavage enzyme
Varpa_5405	ENOG4108IV0	ABC, transporter
Varpa_5406	ENOG4105C0Z	ABC transporter
Varpa_5408	ENOG4105C32	Amino acid ABC transporter (Permease)
Varpa_5410	ENOG4105CHR	reductase
Varpa_5417	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
Varpa_5419	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
Varpa_5420	ENOG4108JU5	Magnesium and cobalt efflux protein
Varpa_5422	ENOG4108YXU	transcriptional regulator AsnC family
Varpa_5424	ENOG4105F87	Dehydratase
Varpa_5425	ENOG4105MIR	Phenylalanine 4-monooxygenase
Varpa_5426	ENOG4105CEY	Amp-dependent synthetase and ligase
Varpa_5428	ENOG4105C5H	ABC transporter
Varpa_5429	ENOG4107RZC	phospholipase d
Varpa_5435	ENOG41076UM	multiple antibiotic resistance (MarC)-related protein
Varpa_5439	ENOG4105E2Q	3-(3-hydroxy-phenyl)propionate hydroxylase
Varpa_5441	ENOG4108K0D	peptidase, M48
Varpa_5449	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
Varpa_5455	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
Varpa_5456	ENOG4105CEY	Amp-dependent synthetase and ligase
Varpa_5459	ENOG4105EQR	Transposase IS116 IS110 IS902
Varpa_5460	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
Varpa_5462	ENOG4105U5Y	Transcriptional regulator
Varpa_5467	ENOG4105CYW	agmatinase
Varpa_5469	ENOG4105CS9	pantothenic acid kinase
Varpa_5470	ENOG4105D82	Glutamate dehydrogenase
Varpa_5472	ENOG4105EW9	transcriptional regulator AsnC family
Varpa_5473	ENOG4105DFA	alanine racemase domain protein
Varpa_5474	ENOG4105CZX	twitching motility protein
Varpa_5475	ENOG4105CZX	twitching motility protein
Varpa_5476	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
Varpa_5478	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
Varpa_5479	ENOG41082RQ	UPF0102 protein
Varpa_5480	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
Varpa_5483	ENOG4108IG5	Transcriptional regulator
Varpa_5484	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
Varpa_5485	ENOG4105BZS	acriflavin resistance protein
Varpa_5486	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
Varpa_5496	ENOG4105K63	Thioredoxin
Varpa_5497	ENOG4107QRT	dEAD DEAH box helicase
Varpa_5498	ENOG4107T0X	DNA ligase
Varpa_5499	ENOG4107T0X	DNA ligase
Varpa_5503	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
Varpa_5504	ENOG4105CNN	ABC, transporter
Varpa_5507	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
Varpa_5508	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
Varpa_5509	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
Varpa_5510	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
Varpa_5511	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
Varpa_5512	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
Varpa_5513	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
Varpa_5514	ENOG4107RAZ	it plays a direct role in the translocation of protons across the membrane (By similarity)
Varpa_5516	ENOG4105F0I	Aminotransferase
Varpa_5517	ENOG4108Z43	UPF0250 protein
Varpa_5518	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
Varpa_5519	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
Varpa_5523	ENOG4105CS6	Rhs element vgr protein
Varpa_5528	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
Varpa_5554	ENOG4105CEY	Amp-dependent synthetase and ligase
Varpa_5555	ENOG41062D9	Histidine kinase
Varpa_5556	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
Varpa_5559	ENOG4105F4P	)-transporter
Varpa_5564	ENOG4108WDE	Fimbrial protein
Varpa_5565	ENOG4105CW0	outer membrane usher protein
Varpa_5566	ENOG4108VCD	Chaperone
Varpa_5567	ENOG4106EAR	Fimbrial protein
Varpa_5568	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
Varpa_5569	ENOG410804D	Sensor Signal Transduction Histidine Kinase
Varpa_5570	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
Varpa_5574	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
Varpa_5575	ENOG41080Z8	PHOSPHOCARRIER protein
Varpa_5579	ENOG4105T86	cytochrome C
Varpa_5583	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
Varpa_5584	ENOG41084PQ	50s ribosomal protein l29
Varpa_5585	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
Varpa_5586	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
Varpa_5587	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
Varpa_5588	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
Varpa_5589	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
Varpa_5590	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
Varpa_5591	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
Varpa_5592	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
Varpa_5595	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
Varpa_5596	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
Varpa_5597	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
Varpa_5598	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
Varpa_5599	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
Varpa_5600	ENOG4105DZ1	carboxypeptidase
Varpa_5601	ENOG4105DHZ	alpha beta
Varpa_5604	ENOG4108YXA	Membrane
Varpa_5605	ENOG4105D52	delta-aminolevulinic acid dehydratase
Varpa_5606	ENOG4105D7N	magnesium and cobalt transport protein CorA
Varpa_5609	ENOG410642W	LysR family Transcriptional regulator
Varpa_5612	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
Varpa_5613	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
Varpa_5617	ENOG4108IV0	ABC, transporter
Varpa_5618	ENOG4105C0Z	ABC transporter
Varpa_5620	ENOG4105C32	Amino acid ABC transporter (Permease)
Varpa_5623	ENOG4108HH9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
Varpa_5624	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
Varpa_5627	ENOG4108194	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
Varpa_5628	ENOG4109066	lysm domain bon superfamily protein
Varpa_5632	ENOG4105CH5	extracellular solute-binding protein, family 7
Varpa_5634	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
Varpa_5634	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
Varpa_5635	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
Varpa_5636	ENOG4105DC8	reductase
Varpa_5637	ENOG4108NKJ	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
Varpa_5638	ENOG4105FYV	Amp nucleosidase
Varpa_5640	ENOG4108ZHR	arsR family transcriptional regulator
Varpa_5644	ENOG4105HEI	LysR family (Transcriptional regulator
Varpa_5647	ENOG4105CJ1	ABC, transporter
Varpa_5649	ENOG4105K56	Transcriptional regulator
Varpa_5650	ENOG4108ZHJ	Organic hydroperoxide resistance protein
Varpa_5652	ENOG4105E27	serine threonine protein kinase
Varpa_5653	ENOG4107RSM	transcriptional regulator
Varpa_5654	ENOG4105CSU	acyl-Coa dehydrogenase
Varpa_5656	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
Varpa_5657	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
Varpa_5663	ENOG4105DEG	Vwa containing coxe family protein
Varpa_5664	ENOG4105RD5	
Varpa_5665	ENOG4105KKX	ATPase associated with various cellular activities aaa_5
Varpa_5669	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
Varpa_5671	ENOG4105C4Y	ABC transporter
Varpa_5672	ENOG4105CC0	LysR family Transcriptional regulator
Varpa_5674	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
Varpa_5676	ENOG4105DHQ	Histidine kinase
Varpa_5677	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
Varpa_5679	ENOG4105FE9	pseudouridine synthase
Varpa_5682	ENOG4108QBV	Monogalactosyldiacylglycerol synthase
Varpa_5686	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
Varpa_5689	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
Varpa_5690	ENOG4105C08	Histidine kinase
Varpa_5693	ENOG4108R80	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity)
Varpa_5694	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
Varpa_5695	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
Varpa_5698	ENOG4105BZS	acriflavin resistance protein
Varpa_5699	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
Varpa_5701	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
Varpa_5704	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
Varpa_5706	ENOG410904N	short-chain dehydrogenase reductase
Varpa_5708	ENOG4105IJJ	transcriptional regulator, crp fnr family
Varpa_5709	ENOG4108IQE	Amp-dependent synthetase and ligase
Varpa_5710	ENOG4105C0Z	ABC transporter
Varpa_5715	ENOG4108IV0	ABC, transporter
Varpa_5723	ENOG4105BZN	citrate synthase
Varpa_5724	ENOG4105BZN	citrate synthase
Varpa_5725	ENOG4108Z0Z	intracellular protease Pfpi family
Varpa_5728	ENOG4108ZXC	Two component transcriptional regulator, luxr family
Varpa_5729	ENOG4105DZG	Dehydrogenase
Varpa_5732	ENOG4105CNA	YD repeat protein
Varpa_5735	ENOG4105DZG	Dehydrogenase
Varpa_5736	ENOG4105E2R	ROK family
Varpa_5737	ENOG4105C2J	ABC transporter
Varpa_5738	ENOG4108HWW	ABC transporter
Varpa_5739	ENOG4105DFW	ABC transporter
Varpa_5741	ENOG4107RUY	(E1 component), alpha subunit
Varpa_5742	ENOG4105CPP	Dehydrogenase, E1 component
Varpa_5743	ENOG4105F6U	Short-chain dehydrogenase reductase Sdr
Varpa_5744	ENOG4105EJC	lysr family transcriptional regulator
Varpa_5747	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
Varpa_5750	ENOG4108UKI	Enoyl-CoA hydratase
Varpa_5751	ENOG4105C1G	acyl-Coa dehydrogenase
Varpa_5756	ENOG4108ZT0	50S ribosomal protein l17
Varpa_5757	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
Varpa_5758	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
Varpa_5759	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
Varpa_5760	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
Varpa_5761	ENOG41067V7	50S ribosomal protein L36
Varpa_5762	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
Varpa_5763	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
Varpa_5764	ENOG4105VPB	50S ribosomal protein L30
Varpa_5765	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
Varpa_5766	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
Varpa_5767	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
Varpa_5768	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
Varpa_5769	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
Varpa_5770	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
Varpa_5771	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
Varpa_5772	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
Varpa_5774	ENOG4105II7	pyrroline-5-carboxylate reductase
Varpa_5776	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
Varpa_5780	ENOG4105CMQ	Chloride channel
Varpa_5785	ENOG410829K	Lysine exporter protein (Lyse ygga)
Varpa_5786	ENOG4105CB5	ATP-dependent DNA helicase recG
Varpa_5787	ENOG4105ECP	epimerase
Varpa_5789	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
Varpa_5790	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
Varpa_5801	ENOG4105SKN	orotidine 5''-phosphate decarboxylase
Varpa_5804	ENOG41072GX	Peptidase M22 Glycoprotease
Varpa_5805	ENOG4105E98	transcriptional regulator DeoR family
Varpa_5806	ENOG4107VIJ	nudix hydrolase
Varpa_5807	ENOG4107RVU	D-Ala-D-Ala carboxypeptidase 3 (S13) family
Varpa_5809	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
Varpa_5810	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
Varpa_5811	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
Varpa_5813	ENOG4105KDP	XRE family
Varpa_5816	ENOG4105C8V	SAICAR synthetase
Varpa_5819	ENOG4108ZRZ	Transcriptional regulator (AsnC family)
Varpa_5820	ENOG4105K6H	D-cysteine desulfhydrase
Varpa_5821	ENOG4105CA9	Pyruvate kinase
Varpa_5822	ENOG4105BZA	Phosphoglycerate kinase
Varpa_5823	ENOG4105DUM	transcriptional regulator, lysR family
Varpa_5826	ENOG4105E2Q	3-(3-hydroxy-phenyl)propionate hydroxylase
Varpa_5829	ENOG4105JN3	extra-cytoplasmic solute receptor family protein
Varpa_5832	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
Varpa_5834	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
Varpa_5836	ENOG4105C79	DNA protecting protein DprA
Varpa_5837	ENOG4108RPN	Protein smg homolog
Varpa_5839	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
Varpa_5840	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
Varpa_5843	ENOG4108YXU	transcriptional regulator AsnC family
Varpa_5848	ENOG4106PMH	Extracellular solute-binding protein family 3
Varpa_5849	ENOG4105E5Q	amino acid AbC transporter
Varpa_5850	ENOG4107SFI	Major Facilitator superfamily
Varpa_5853	ENOG4108I05	Binding-protein-dependent transport systems, inner membrane component
Varpa_5859	ENOG4107YYT	May reduce aminoacrylate peracid to aminoacrylate. Required to remove a toxic intermediate produce by the pyrimidine nitrogen degradation (By similarity)
Varpa_5861	ENOG4105QG4	Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity)
Varpa_5862	ENOG4105FB2	class II Aldolase
Varpa_5863	ENOG4105G63	Type III effector Hrp-dependent
Varpa_5864	ENOG4105ZXK	Dehydrogenase
Varpa_5865	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
Varpa_5866	ENOG4108YXU	transcriptional regulator AsnC family
Varpa_5872	ENOG4108ZXC	Two component transcriptional regulator, luxr family
Varpa_5873	ENOG4105BZU	Histidine kinase
Varpa_5876	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
Varpa_5877	ENOG4105K6T	rare lipoprotein A
Varpa_5878	ENOG4105MDH	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
Varpa_5879	ENOG4108KPJ	rna polymerase sigma factor
Varpa_5884	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
Varpa_5887	ENOG4108U78	Glutathione S-transferase
Varpa_5888	ENOG4107QTF	adenylosuccinate lyase
Varpa_5890	ENOG4105GAV	receptor
Varpa_5891	ENOG4108VWS	Yaeq family
Varpa_5894	ENOG4108ZCF	integral membrane protein
Varpa_5896	ENOG41086DT	Membrane protein of unknown function
Varpa_5897	ENOG4105ERG	peptidase m48, ste24p
Varpa_5898	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
Varpa_5908	ENOG4105KHS	type IV fimbrial pilin protein
Varpa_5909	ENOG4107YM4	Beta-lactamase domain-containing protein
Varpa_5910	ENOG4105F8J	Adenylate Guanylate cyclase
Varpa_5911	ENOG4108UW8	fha domain-containing protein
Varpa_5912	ENOG4108ZF3	Phosphatase
Varpa_5913	ENOG4108ZCF	integral membrane protein
Varpa_5914	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
Varpa_5915	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
Varpa_5916	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
Varpa_5918	ENOG4108Z12	YiaAB two helix domain-containing protein
Varpa_5920	ENOG4108004	Modulates RecA activity (By similarity)
Varpa_5921	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
Varpa_5925	ENOG4105DHQ	Histidine kinase
Varpa_5928	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
Varpa_5930	ENOG4105C9U	ATP-dependent DNA helicase RecQ
Varpa_5936	ENOG4108SUT	Major Facilitator Superfamily
Varpa_5938	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
Varpa_5939	ENOG4105C1J	atp-dependent rna helicase
Varpa_5943	ENOG4108KTG	Membrane protein, drug metabolite transporter
Varpa_5945	ENOG4108WYP	Transcriptional regulator
Varpa_5949	ENOG4105CTU	Proline racemase
Varpa_5950	ENOG4105CP9	extracellular ligand-binding receptor
Varpa_5951	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
Varpa_5952	ENOG4105CAF	HipA N-terminal domain protein
Varpa_5955	ENOG4105CH2	amidohydrolase
Varpa_5956	ENOG4105EUB	pirin domain protein
Varpa_5959	ENOG4108YZY	peptidylprolyl cis-trans isomerase
Varpa_5962	ENOG4105EUB	pirin domain protein
Varpa_5966	ENOG4105EJC	lysr family transcriptional regulator
Varpa_5967	ENOG4105D4Y	metalloprotease
Varpa_5970	ENOG4105VRH	Antibiotic biosynthesis monooxygenase
Varpa_5973	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
Varpa_5974	ENOG4105CV1	Transketolase (EC 2.2.1.1)
Varpa_5975	ENOG4105X3E	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
Varpa_5976	ENOG4108S0S	Nucleotidyl transferase
Varpa_5977	ENOG4107RAQ	aminopeptidase
Varpa_5981	ENOG4108JQB	penicillin-binding protein 1C
Varpa_5982	ENOG4105DN3	alpha-2-macroglobulin domain protein
Varpa_5991	ENOG4105C6K	Malic enzyme
Varpa_5994	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
Varpa_5995	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
Varpa_5996	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
Varpa_5997	ENOG4105EHM	Aminoglycoside phosphotransferase
Varpa_5998	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
Varpa_6001	ENOG4105DXI	Major Facilitator superfamily
Varpa_6002	ENOG4105E5G	Alpha beta hydrolase fold
Varpa_6006	ENOG4105EYW	Ion transport protein
Varpa_6007	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
Varpa_6008	ENOG4105DWV	Homoserine O-trans-acetylase
Varpa_6009	ENOG4105DWV	Homoserine O-trans-acetylase
Varpa_6011	ENOG4105VFU	Rna-binding protein
Varpa_6012	ENOG4105EMU	Dehydrogenase
Varpa_6014	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
Varpa_6015	ENOG4105C2X	Arabinose 5-phosphate isomerase
Varpa_6018	ENOG4105CSV	Glutaminase
Varpa_6019	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
Varpa_6020	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
Varpa_6021	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
Varpa_6022	ENOG4105X5M	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)