locus-tag	class	description
NWF24_00035	COG1459	type II secretion system
NWF24_00090	COG4795	General secretion pathway protein
NWF24_00105	COG4213	ABC transporter substrate-binding protein
NWF24_00110	COG4214	carbohydrate transport
NWF24_00115	COG1129	ABC transporter
NWF24_00120	COG1940	carbohydrate kinase activity
NWF24_00155	COG0318	PFAM AMP-dependent synthetase and ligase
NWF24_00185	COG1022	Amp-dependent synthetase and ligase
NWF24_00190	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NWF24_00200	COG1028	Short-chain dehydrogenase reductase Sdr
NWF24_00225	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
NWF24_00240	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NWF24_00250	COG0583	DNA-binding transcription factor activity
NWF24_00260	COG1529	Aldehyde oxidase and xanthine dehydrogenase
NWF24_00265	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
NWF24_00270	COG2080	2 iron, 2 sulfur cluster binding
NWF24_00280	COG2205	protein histidine kinase activity
NWF24_00285	COG0745	RESPONSE REGULATOR receiver
NWF24_00290	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NWF24_00310	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NWF24_00320	COG1056	cytidyltransferase-related domain
NWF24_00320	COG1051	belongs to the nudix hydrolase family
NWF24_00325	COG1187	pseudouridine synthase activity
NWF24_00340	COG0642	Histidine kinase
NWF24_00350	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
NWF24_00360	COG0583	DNA-binding transcription factor activity
NWF24_00365	COG1840	ABC-type Fe3 transport system, periplasmic component
NWF24_00405	COG0326	Molecular chaperone. Has ATPase activity
NWF24_00450	COG1804	L-carnitine dehydratase bile acid-inducible protein F
NWF24_00455	COG3181	Tripartite tricarboxylate transporter family receptor
NWF24_00460	COG1960	acyl-CoA dehydrogenase activity
NWF24_00465	COG0583	DNA-binding transcription factor activity
NWF24_00470	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
NWF24_00480	COG1764	response to oxidative stress
NWF24_00485	COG1846	Transcriptional regulator
NWF24_00490	COG0789	Transcriptional regulator
NWF24_00500	COG1131	(ABC) transporter
NWF24_00525	COG0625	glutathione transferase activity
NWF24_00540	COG0640	Transcriptional regulator
NWF24_00555	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NWF24_00575	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
NWF24_00580	COG4208	sulfate ABC transporter
NWF24_00590	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NWF24_00605	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NWF24_00605	COG0574	Belongs to the PEP-utilizing enzyme family
NWF24_00630	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
NWF24_00640	COG1652	LysM domain
NWF24_00645	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
NWF24_00660	COG1250	3-hydroxyacyl-CoA dehydrogenase
NWF24_00665	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
NWF24_00680	COG0559	Belongs to the binding-protein-dependent transport system permease family
NWF24_00715	COG2095	MarC family integral membrane protein
NWF24_00720	COG1028	Short-chain dehydrogenase reductase Sdr
NWF24_00730	COG0412	Dienelactone hydrolase
NWF24_00735	COG0583	DNA-binding transcription factor activity
NWF24_00750	COG0598	Magnesium transport protein CorA
NWF24_00760	COG1981	membrane
NWF24_00775	COG2945	thiolester hydrolase activity
NWF24_00780	COG1686	Belongs to the peptidase S11 family
NWF24_00785	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NWF24_00790	COG0049	tRNA binding
NWF24_00795	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NWF24_00805	COG0051	transcription antitermination factor activity, RNA binding
NWF24_00820	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NWF24_00825	COG0088	Forms part of the polypeptide exit tunnel
NWF24_00830	COG0089	rRNA binding
NWF24_00835	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NWF24_00840	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NWF24_00845	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NWF24_00850	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NWF24_00855	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NWF24_00860	COG0255	Belongs to the universal ribosomal protein uL29 family
NWF24_00865	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NWF24_00870	COG0678	peroxiredoxin activity
NWF24_00885	COG3909	cytochrome
NWF24_00890	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NWF24_00905	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
NWF24_00910	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NWF24_00935	COG0745	RESPONSE REGULATOR receiver
NWF24_00940	COG2205	protein histidine kinase activity
NWF24_00945	COG2130	NADP-dependent
NWF24_00970	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
NWF24_00990	COG2205	protein histidine kinase activity
NWF24_00995	COG0318	PFAM AMP-dependent synthetase and ligase
NWF24_01010	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NWF24_01020	COG2205	protein histidine kinase activity
NWF24_01025	COG0745	RESPONSE REGULATOR receiver
NWF24_01050	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
NWF24_01055	COG0321	lipoyl(octanoyl) transferase activity
NWF24_01060	COG2921	Belongs to the UPF0250 family
NWF24_01065	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NWF24_01075	COG0356	it plays a direct role in the translocation of protons across the membrane
NWF24_01085	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NWF24_01090	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NWF24_01095	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NWF24_01100	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NWF24_01110	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NWF24_01115	COG0355	proton-transporting ATP synthase activity, rotational mechanism
NWF24_01130	COG1172	Belongs to the binding-protein-dependent transport system permease family
NWF24_01135	COG1879	ABC-type sugar transport system periplasmic component
NWF24_01140	COG0673	inositol 2-dehydrogenase activity
NWF24_01155	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
NWF24_01155	COG1793	dna ligase
NWF24_01160	COG1793	dna ligase
NWF24_01160	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
NWF24_01165	COG1201	RNA secondary structure unwinding
NWF24_01170	COG3118	belongs to the thioredoxin family
NWF24_01205	COG1079	Belongs to the binding-protein-dependent transport system permease family
NWF24_01215	COG3845	ABC transporter
NWF24_01235	COG1309	transcriptional regulator
NWF24_01240	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NWF24_01245	COG0778	Nitroreductase
NWF24_01250	COG2267	carboxylic ester hydrolase activity
NWF24_01255	COG0251	oxidation-reduction process
NWF24_01260	COG1335	isochorismatase
NWF24_01265	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NWF24_01300	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NWF24_01305	COG1309	transcriptional regulator
NWF24_01315	COG0483	inositol monophosphate 1-phosphatase activity
NWF24_01325	COG0791	NLP P60 protein
NWF24_01325	COG1388	LysM domain
NWF24_01345	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NWF24_01350	COG0792	nuclease activity
NWF24_01355	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
NWF24_01365	COG2084	Dehydrogenase
NWF24_01370	COG0789	Transcriptional regulator
NWF24_01405	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
NWF24_01425	COG1289	transmembrane transporter activity
NWF24_01460	COG0714	Associated with various cellular activities
NWF24_01475	COG0010	Belongs to the arginase family
NWF24_01480	COG1505	serine-type exopeptidase activity
NWF24_01500	COG1309	transcriptional regulator
NWF24_01540	COG2124	cytochrome p450
NWF24_01540	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
NWF24_01555	COG0318	PFAM AMP-dependent synthetase and ligase
NWF24_01560	COG0439	Biotin carboxylase
NWF24_01580	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
NWF24_01590	COG1462	curli production assembly transport component CsgG
NWF24_01655	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NWF24_01705	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NWF24_01710	COG0488	(ABC) transporter
NWF24_01745	COG0318	PFAM AMP-dependent synthetase and ligase
NWF24_01750	COG3186	Phenylalanine-4-hydroxylase
NWF24_01765	COG1522	sequence-specific DNA binding
NWF24_01775	COG4535	Mg2 and Co2 transporter CorC
NWF24_01780	COG0815	Transfers the fatty acyl group on membrane lipoproteins
NWF24_01790	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NWF24_01870	COG0752	glycyl-tRNA synthetase alpha subunit
NWF24_01875	COG0751	glycine-tRNA ligase activity
NWF24_01880	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
NWF24_01915	COG0789	Transcriptional regulator
NWF24_01920	COG0288	reversible hydration of carbon dioxide
NWF24_01925	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
NWF24_01930	COG0183	Belongs to the thiolase family
NWF24_01940	COG1960	acyl-CoA dehydrogenase activity
NWF24_01955	COG5002	protein histidine kinase activity
NWF24_01960	COG3012	SEC-C Motif Domain Protein
NWF24_01965	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
NWF24_01970	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NWF24_01985	COG1960	acyl-CoA dehydrogenase activity
NWF24_01990	COG0318	PFAM AMP-dependent synthetase and ligase
NWF24_01995	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
NWF24_02005	COG1024	Enoyl-CoA hydratase
NWF24_02030	COG0625	glutathione transferase activity
NWF24_02040	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
NWF24_02045	COG1414	Transcriptional regulator
NWF24_02060	COG1804	L-carnitine dehydratase bile acid-inducible protein F
NWF24_02070	COG1254	Belongs to the acylphosphatase family
NWF24_02080	COG1280	lysine exporter protein (LysE YggA)
NWF24_02100	COG0477	Major facilitator Superfamily
NWF24_02120	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
NWF24_02125	COG1012	belongs to the aldehyde dehydrogenase family
NWF24_02135	COG1177	transmembrane transport
NWF24_02140	COG1176	ABC-type spermidine putrescine transport system, permease component I
NWF24_02150	COG3842	ATPase activity
NWF24_02155	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NWF24_02160	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NWF24_02165	COG2423	ornithine cyclodeaminase activity
NWF24_02220	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
NWF24_02235	COG3254	rhamnose metabolic process
NWF24_02240	COG4948	Mandelate Racemase Muconate Lactonizing
NWF24_02260	COG2814	Major facilitator Superfamily
NWF24_02270	COG1126	abc transporter atp-binding protein
NWF24_02300	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NWF24_02305	COG0251	oxidation-reduction process
NWF24_02335	COG3243	poly(R)-hydroxyalkanoic acid synthase
NWF24_02365	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
NWF24_02380	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
NWF24_02385	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
NWF24_02390	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NWF24_02395	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
NWF24_02400	COG0316	Belongs to the HesB IscA family
NWF24_02405	COG2814	Major facilitator Superfamily
NWF24_02410	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
NWF24_02420	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NWF24_02435	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NWF24_02440	COG1490	D-aminoacyl-tRNA deacylase activity
NWF24_02445	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NWF24_02450	COG1702	phosphate starvation-inducible protein PhoH
NWF24_02455	COG0632	four-way junction helicase activity
NWF24_02465	COG4589	Belongs to the CDS family
NWF24_02480	COG0671	phosphoesterase, PA-phosphatase related
NWF24_02480	COG2453	phosphatase
NWF24_02485	COG2267	carboxylic ester hydrolase activity
NWF24_02490	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NWF24_02495	COG2255	four-way junction helicase activity
NWF24_02520	COG1960	acyl-CoA dehydrogenase activity
NWF24_02530	COG1804	L-carnitine dehydratase bile acid-inducible protein F
NWF24_02535	COG0318	PFAM AMP-dependent synthetase and ligase
NWF24_02560	COG2909	trisaccharide binding
NWF24_02575	COG0183	Belongs to the thiolase family
NWF24_02580	COG3706	GGDEF domain
NWF24_02600	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
NWF24_02610	COG0318	PFAM AMP-dependent synthetase and ligase
NWF24_02625	COG1999	signal sequence binding
NWF24_02655	COG1024	Enoyl-CoA hydratase
NWF24_02660	COG2076	Multidrug Resistance protein
NWF24_02680	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NWF24_02690	COG1869	D-ribose catabolic process
NWF24_02695	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NWF24_02700	COG1609	Transcriptional regulator
NWF24_02705	COG1172	Belongs to the binding-protein-dependent transport system permease family
NWF24_02710	COG1129	ABC transporter
NWF24_02715	COG1879	ABC-type sugar transport system periplasmic component
NWF24_02720	COG0012	GTP binding
NWF24_02730	COG1238	metal cluster binding
NWF24_02735	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NWF24_02745	COG0138	bifunctional purine biosynthesis protein purh
NWF24_02755	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
NWF24_02765	COG1773	rubredoxin
NWF24_02785	COG0840	transmembrane signaling receptor activity
NWF24_02790	COG0784	Response regulator, receiver
NWF24_02790	COG0643	Histidine kinase
NWF24_02790	COG2198	Histidine kinase
NWF24_02795	COG0415	Belongs to the DNA photolyase family
NWF24_02800	COG1678	Uncharacterized ACR, COG1678
NWF24_02805	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NWF24_02810	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
NWF24_02815	COG0540	Belongs to the ATCase OTCase family
NWF24_02855	COG3842	ATPase activity
NWF24_02865	COG1176	ABC-type spermidine putrescine transport system, permease component I
NWF24_02915	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
NWF24_02920	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NWF24_02925	COG1804	L-carnitine dehydratase bile acid-inducible protein F
NWF24_02930	COG2030	dehydratase
NWF24_02970	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NWF24_03020	COG4191	Histidine kinase
NWF24_03025	COG1804	L-carnitine dehydratase bile acid-inducible protein F
NWF24_03030	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NWF24_03035	COG0045	succinate-CoA ligase (ADP-forming) activity
NWF24_03040	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
NWF24_03045	COG0179	Fumarylacetoacetate (FAA) hydrolase
NWF24_03050	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NWF24_03055	COG0469	pyruvate kinase activity
NWF24_03090	COG3383	formate dehydrogenase (NAD+) activity
NWF24_03095	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
NWF24_03135	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NWF24_03145	COG3485	protocatechuate 3,4-dioxygenase
NWF24_03150	COG3485	protocatechuate 3,4-dioxygenase
NWF24_03155	COG0583	DNA-binding transcription factor activity
NWF24_03175	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
NWF24_03185	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NWF24_03245	COG4964	Belongs to the GSP D family
NWF24_03270	COG3063	Type IV pilus biogenesis stability protein PilW
NWF24_03290	COG1012	belongs to the aldehyde dehydrogenase family
NWF24_03300	COG1137	ATPase activity
NWF24_03330	COG1414	Transcriptional regulator
NWF24_03340	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
NWF24_03345	COG0183	Belongs to the thiolase family
NWF24_03355	COG2205	protein histidine kinase activity
NWF24_03380	COG0693	protein deglycase activity
NWF24_03410	COG2423	ornithine cyclodeaminase activity
NWF24_03415	COG1073	alpha beta
NWF24_03440	COG4650	regulator
NWF24_03460	COG1690	Belongs to the RtcB family
NWF24_03470	COG1234	tRNA 3'-trailer cleavage
NWF24_03475	COG3541	Predicted nucleotidyltransferase
NWF24_03480	COG0430	RNA-3'-phosphate cyclase activity
NWF24_03500	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NWF24_03520	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
NWF24_03545	COG3485	protocatechuate 3,4-dioxygenase
NWF24_03565	COG5507	3-demethylubiquinone-9 3-methyltransferase
NWF24_03585	COG2764	glyoxalase bleomycin resistance protein dioxygenase
NWF24_03600	COG1960	acyl-CoA dehydrogenase activity
NWF24_03640	COG1024	Enoyl-CoA hydratase
NWF24_03660	COG0489	protein tyrosine kinase activity
NWF24_03675	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
NWF24_03680	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NWF24_03685	COG2226	methyltransferase
NWF24_03695	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
NWF24_03700	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NWF24_03710	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
NWF24_03745	COG0109	protoheme IX farnesyltransferase activity
NWF24_03750	COG1999	signal sequence binding
NWF24_03755	COG4335	DNA alkylation repair
NWF24_03760	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NWF24_03770	COG2197	response regulator
NWF24_03775	COG0784	Response regulator, receiver
NWF24_03775	COG2205	protein histidine kinase activity
NWF24_03785	COG0612	Peptidase, M16
NWF24_03790	COG0612	Peptidase, M16
NWF24_03805	COG0742	ribosomal rna small subunit methyltransferase
NWF24_03810	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NWF24_03815	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
NWF24_03820	COG1984	allophanate hydrolase subunit 2
NWF24_03825	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
NWF24_03830	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
NWF24_03835	COG2267	carboxylic ester hydrolase activity
NWF24_03850	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
NWF24_03865	COG0583	DNA-binding transcription factor activity
NWF24_03875	COG0154	amidase activity
NWF24_03880	COG0747	negative chemotaxis
NWF24_03885	COG0747	negative chemotaxis
NWF24_03890	COG4608	Belongs to the ABC transporter superfamily
NWF24_03900	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NWF24_03910	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
NWF24_03920	COG0193	aminoacyl-tRNA hydrolase activity
NWF24_03935	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
NWF24_03940	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NWF24_03950	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
NWF24_03965	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
NWF24_03970	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
NWF24_03980	COG1660	Displays ATPase and GTPase activities
NWF24_03985	COG0497	DNA recombination
NWF24_03990	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NWF24_03995	COG1420	regulation of RNA biosynthetic process
NWF24_04020	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NWF24_04025	COG1758	RNA polymerase activity
NWF24_04030	COG0194	GDP metabolic process
NWF24_04035	COG1561	YicC-like family, N-terminal region
NWF24_04050	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
NWF24_04055	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NWF24_04060	COG0635	Involved in the biosynthesis of porphyrin-containing compound
NWF24_04070	COG3706	GGDEF domain
NWF24_04070	COG5001	Diguanylate cyclase
NWF24_04070	COG4251	negative regulation of phosphorylation
NWF24_04070	COG2203	Gaf domain
NWF24_04085	COG0417	DNA replication proofreading
NWF24_04090	COG1131	(ABC) transporter
NWF24_04095	COG0842	Transport permease protein
NWF24_04120	COG1172	Belongs to the binding-protein-dependent transport system permease family
NWF24_04125	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NWF24_04130	COG4154	Belongs to the RbsD FucU family
NWF24_04135	COG1012	belongs to the aldehyde dehydrogenase family
NWF24_04140	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
NWF24_04145	COG1349	DNA-binding transcription factor activity
NWF24_04155	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NWF24_04165	COG0596	Alpha beta hydrolase
NWF24_04175	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NWF24_04185	COG0583	DNA-binding transcription factor activity
NWF24_04230	COG1309	transcriptional regulator
NWF24_04240	COG4774	siderophore transport
NWF24_04275	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
NWF24_04280	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
NWF24_04285	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
NWF24_04290	COG2205	protein histidine kinase activity
NWF24_04295	COG0745	RESPONSE REGULATOR receiver
NWF24_04320	COG1012	belongs to the aldehyde dehydrogenase family
NWF24_04325	COG2721	sulfolactate sulfo-lyase activity
NWF24_04360	COG4948	Mandelate Racemase Muconate Lactonizing
NWF24_04365	COG1028	Short-chain dehydrogenase reductase Sdr
NWF24_04375	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NWF24_04380	COG0583	DNA-binding transcription factor activity
NWF24_04385	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
NWF24_04390	COG0436	Aminotransferase
NWF24_04400	COG0511	ligase activity, forming carbon-carbon bonds
NWF24_04405	COG0439	Biotin carboxylase
NWF24_04410	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
NWF24_04415	COG1984	allophanate hydrolase subunit 2
NWF24_04425	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
NWF24_04430	COG4221	oxidoreductase activity
NWF24_04435	COG0765	amino acid transport
NWF24_04440	COG0765	amino acid transport
NWF24_04450	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NWF24_04455	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
NWF24_04460	COG0745	RESPONSE REGULATOR receiver
NWF24_04615	COG1522	sequence-specific DNA binding
NWF24_04625	COG1959	2 iron, 2 sulfur cluster binding
NWF24_04640	COG1289	transmembrane transporter activity
NWF24_04665	COG1917	Cupin 2, conserved barrel domain protein
NWF24_04665	COG4977	sequence-specific DNA binding
NWF24_04685	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
NWF24_04690	COG0745	RESPONSE REGULATOR receiver
NWF24_04695	COG2205	protein histidine kinase activity
NWF24_04710	COG0745	RESPONSE REGULATOR receiver
NWF24_04745	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NWF24_04745	COG2205	protein histidine kinase activity
NWF24_04750	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
NWF24_04760	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
NWF24_04765	COG0830	nickel cation binding
NWF24_04770	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
NWF24_04775	COG0804	urea catabolic process
NWF24_04780	COG0832	Belongs to the urease beta subunit family
NWF24_04790	COG0831	urea catabolic process
NWF24_04810	COG0583	DNA-binding transcription factor activity
NWF24_04815	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
NWF24_04820	COG3181	Tripartite tricarboxylate transporter family receptor
NWF24_04830	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
NWF24_04840	COG2423	ornithine cyclodeaminase activity
NWF24_04850	COG0653	protein targeting
NWF24_04855	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
NWF24_04865	COG0494	nUDIX hydrolase
NWF24_04875	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
NWF24_04875	COG2755	lipolytic protein G-D-S-L family
NWF24_04880	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
NWF24_04885	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
NWF24_04895	COG1696	Membrane protein involved in D-alanine export
NWF24_04905	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
NWF24_04925	COG0142	geranyltranstransferase activity
NWF24_04930	COG0261	This protein binds to 23S rRNA in the presence of protein L20
NWF24_04935	COG0211	Belongs to the bacterial ribosomal protein bL27 family
NWF24_04940	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NWF24_04945	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NWF24_04955	COG0494	nUDIX hydrolase
NWF24_04960	COG0442	prolyl-tRNA aminoacylation
NWF24_04965	COG0741	lytic transglycosylase activity
NWF24_04970	COG1253	flavin adenine dinucleotide binding
NWF24_04980	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
NWF24_04985	COG2890	protein-(glutamine-N5) methyltransferase activity
NWF24_04990	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NWF24_04995	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
NWF24_05015	COG4120	Belongs to the binding-protein-dependent transport system permease family
NWF24_05025	COG1522	sequence-specific DNA binding
NWF24_05030	COG1511	domain protein
NWF24_05030	COG3264	Mechanosensitive ion channel
NWF24_05035	COG0584	glycerophosphoryl diester phosphodiesterase
NWF24_05040	COG3842	ATPase activity
NWF24_05045	COG0395	ABC-type sugar transport system, permease component
NWF24_05050	COG1175	transmembrane transport
NWF24_05060	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
NWF24_05095	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
NWF24_05100	COG4145	pantothenate transmembrane transporter activity
NWF24_05115	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
NWF24_05120	COG0494	nUDIX hydrolase
NWF24_05155	COG2823	Periplasmic or secreted lipoprotein
NWF24_05190	COG2197	response regulator
NWF24_05195	COG2197	response regulator
NWF24_05200	COG2982	Protein involved in outer membrane biogenesis
NWF24_05205	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
NWF24_05210	COG0793	Belongs to the peptidase S41A family
NWF24_05215	COG0588	phosphoglycerate mutase activity
NWF24_05220	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NWF24_05230	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
NWF24_05235	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
NWF24_05245	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
NWF24_05250	COG0720	synthase
NWF24_05255	COG0602	queuosine metabolic process
NWF24_05260	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
NWF24_05265	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
NWF24_05270	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
NWF24_05290	COG0659	secondary active sulfate transmembrane transporter activity
NWF24_05295	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NWF24_05295	COG1024	Enoyl-CoA hydratase
NWF24_05305	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NWF24_05305	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NWF24_05310	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NWF24_05320	COG0473	3-isopropylmalate dehydrogenase activity
NWF24_05330	COG3132	Protein of unknown function, DUF480
NWF24_05340	COG1522	sequence-specific DNA binding
NWF24_05345	COG1473	amidohydrolase
NWF24_05360	COG0489	protein tyrosine kinase activity
NWF24_05365	COG0583	DNA-binding transcription factor activity
NWF24_05370	COG2223	nitrite transmembrane transporter activity
NWF24_05395	COG4149	molybdate abc transporter
NWF24_05400	COG0725	ABC transporter, periplasmic molybdate-binding protein
NWF24_05420	COG0243	molybdopterin cofactor binding
NWF24_05430	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
NWF24_05435	COG2831	hemolysin activation secretion protein
NWF24_05445	COG3210	domain, Protein
NWF24_05445	COG3210	domain, Protein
NWF24_05455	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
NWF24_05460	COG3639	organic phosphonate transmembrane transporter activity
NWF24_05465	COG3639	organic phosphonate transmembrane transporter activity
NWF24_05470	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
NWF24_05475	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
NWF24_05480	COG0709	Synthesizes selenophosphate from selenide and ATP
NWF24_05490	COG3276	selenocysteine insertion sequence binding
NWF24_05520	COG2864	formate dehydrogenase
NWF24_05525	COG0437	4 iron, 4 sulfur cluster binding
NWF24_05540	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
NWF24_05555	COG0583	DNA-binding transcription factor activity
NWF24_05560	COG0477	Major facilitator Superfamily
NWF24_05565	COG0583	DNA-binding transcription factor activity
NWF24_05575	COG1028	Short-chain dehydrogenase reductase Sdr
NWF24_05580	COG2900	Belongs to the SlyX family
NWF24_05585	COG1272	protein, Hemolysin III
NWF24_05590	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
NWF24_05605	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
NWF24_05610	COG1845	cytochrome c oxidase, subunit III
NWF24_05615	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NWF24_05620	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
NWF24_05625	COG0477	Major facilitator Superfamily
NWF24_05630	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NWF24_05640	COG3491	Belongs to the iron ascorbate-dependent oxidoreductase family
NWF24_05650	COG0765	amino acid transport
NWF24_05655	COG0765	amino acid transport
NWF24_05660	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NWF24_05665	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
NWF24_05680	COG1193	negative regulation of DNA recombination
NWF24_05685	COG2003	Belongs to the UPF0758 family
NWF24_05690	COG1047	Peptidyl-prolyl cis-trans
NWF24_05695	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
NWF24_05700	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NWF24_05705	COG2764	glyoxalase bleomycin resistance protein dioxygenase
NWF24_05710	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NWF24_05775	COG1815	bacterial-type flagellum-dependent cell motility
NWF24_05780	COG1558	bacterial-type flagellum-dependent cell motility
NWF24_05790	COG1749	Flagellar hook protein flgE
NWF24_05805	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
NWF24_05810	COG1706	bacterial-type flagellum-dependent cell motility
NWF24_05820	COG0835	chemotaxis
NWF24_05850	COG0840	transmembrane signaling receptor activity
NWF24_05855	COG0840	transmembrane signaling receptor activity
NWF24_05865	COG1256	bacterial-type flagellum assembly
NWF24_05895	COG0154	amidase activity
NWF24_05915	COG1987	bacterial-type flagellum assembly
NWF24_05930	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
NWF24_05940	COG1580	Controls the rotational direction of flagella during chemotaxis
NWF24_05950	COG2882	bacterial-type flagellum organization
NWF24_05955	COG1157	protein secretion by the type III secretion system
NWF24_05975	COG1677	Flagellar hook-basal body complex protein FliE
NWF24_05990	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
NWF24_06010	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
NWF24_06040	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
NWF24_06045	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
NWF24_06050	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
NWF24_06065	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
NWF24_06075	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
NWF24_06090	COG1191	sigma factor activity
NWF24_06100	COG3387	PFAM Glycoside hydrolase 15-related
NWF24_06110	COG2084	Dehydrogenase
NWF24_06115	COG3265	gluconokinase activity
NWF24_06120	COG1028	Short-chain dehydrogenase reductase Sdr
NWF24_06125	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NWF24_06130	COG1063	alcohol dehydrogenase
NWF24_06160	COG1609	Transcriptional regulator
NWF24_06165	COG3386	PFAM SMP-30 Gluconolaconase
NWF24_06190	COG1950	PFAM Membrane protein of
NWF24_06200	COG5002	protein histidine kinase activity
NWF24_06205	COG2197	response regulator
NWF24_06210	COG0180	Tryptophanyl-tRNA synthetase
NWF24_06215	COG1994	Peptidase M50
NWF24_06220	COG0009	L-threonylcarbamoyladenylate synthase
NWF24_06230	COG0613	PHP domain protein
NWF24_06240	COG0306	phosphate transporter
NWF24_06265	COG0477	Major facilitator Superfamily
NWF24_06300	COG2814	Major facilitator Superfamily
NWF24_06320	COG3540	Alkaline phosphatase
NWF24_06325	COG0667	Aldo Keto reductase
NWF24_06340	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NWF24_06350	COG5002	protein histidine kinase activity
NWF24_06360	COG2814	Major facilitator Superfamily
NWF24_06425	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
NWF24_06435	COG0791	NLP P60 protein
NWF24_06450	COG1360	Flagellar Motor Protein
NWF24_06470	COG1966	Carbon starvation protein
NWF24_06475	COG2879	small protein
NWF24_06515	COG0583	DNA-binding transcription factor activity
NWF24_06550	COG0829	nickel cation binding
NWF24_06560	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
NWF24_06570	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NWF24_06595	COG1733	regulation of RNA biosynthetic process
NWF24_06600	COG2084	Dehydrogenase
NWF24_06605	COG2267	carboxylic ester hydrolase activity
NWF24_06625	COG0583	DNA-binding transcription factor activity
NWF24_06645	COG0745	RESPONSE REGULATOR receiver
NWF24_06670	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NWF24_06675	COG1116	anion transmembrane transporter activity
NWF24_06695	COG2084	Dehydrogenase
NWF24_06700	COG3622	Belongs to the hyi family
NWF24_06705	COG3960	tartronate-semialdehyde synthase activity
NWF24_06710	COG0583	DNA-binding transcription factor activity
NWF24_06725	COG0628	permease
NWF24_06735	COG3209	COG3209 Rhs family protein
NWF24_06755	COG1301	dicarboxylic acid transport
NWF24_06765	COG0477	Major facilitator Superfamily
NWF24_06790	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
NWF24_06810	COG2197	response regulator
NWF24_06815	COG2205	protein histidine kinase activity
NWF24_06815	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NWF24_06835	COG4566	intracellular signal transduction
NWF24_06850	COG0583	DNA-binding transcription factor activity
NWF24_06880	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NWF24_06890	COG0154	amidase activity
NWF24_06895	COG0747	negative chemotaxis
NWF24_06900	COG4608	Belongs to the ABC transporter superfamily
NWF24_06905	COG0444	Belongs to the ABC transporter superfamily
NWF24_06910	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NWF24_06920	COG0473	3-isopropylmalate dehydrogenase activity
NWF24_06930	COG0656	L-ascorbic acid biosynthetic process
NWF24_06935	COG2233	PERMEase
NWF24_06940	COG5001	Diguanylate cyclase
NWF24_06955	COG1953	Uracil, thiamine, allantoin
NWF24_06970	COG0861	Integral membrane protein TerC family
NWF24_06975	COG0583	DNA-binding transcription factor activity
NWF24_06980	COG5002	protein histidine kinase activity
NWF24_07005	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NWF24_07020	COG2186	Transcriptional regulator
NWF24_07025	COG2351	hydroxyisourate hydrolase activity
NWF24_07065	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
NWF24_07080	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NWF24_07145	COG1529	Aldehyde oxidase and xanthine dehydrogenase
NWF24_07155	COG2252	PERMEase
NWF24_07160	COG3845	ABC transporter
NWF24_07180	COG0515	serine threonine protein kinase
NWF24_07195	COG1944	ATP diphosphatase activity
NWF24_07220	COG0154	amidase activity
NWF24_07235	COG0404	The glycine cleavage system catalyzes the degradation of glycine
NWF24_07255	COG3842	ATPase activity
NWF24_07260	COG1840	ABC-type Fe3 transport system, periplasmic component
NWF24_07275	COG1012	belongs to the aldehyde dehydrogenase family
NWF24_07285	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NWF24_07290	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NWF24_07295	COG1126	abc transporter atp-binding protein
NWF24_07300	COG0765	amino acid transport
NWF24_07315	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
NWF24_07320	COG2814	Major facilitator Superfamily
NWF24_07325	COG0583	DNA-binding transcription factor activity
NWF24_07335	COG2366	antibiotic biosynthetic process
NWF24_07350	COG4221	oxidoreductase activity
NWF24_07380	COG0583	DNA-binding transcription factor activity
NWF24_07395	COG0402	S-adenosylhomocysteine deaminase activity
NWF24_07400	COG0717	Belongs to the dCTP deaminase family
NWF24_07405	COG2321	neutral zinc metallopeptidase
NWF24_07410	COG0513	Belongs to the DEAD box helicase family
NWF24_07420	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NWF24_07430	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
NWF24_07435	COG1960	acyl-CoA dehydrogenase activity
NWF24_07440	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
NWF24_07445	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NWF24_07455	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
NWF24_07460	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
NWF24_07480	COG2207	Transcriptional regulator
NWF24_07500	COG0583	DNA-binding transcription factor activity
NWF24_07510	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
NWF24_07515	COG1253	flavin adenine dinucleotide binding
NWF24_07525	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
NWF24_07530	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NWF24_07550	COG2223	nitrite transmembrane transporter activity
NWF24_07555	COG2207	Transcriptional regulator
NWF24_07625	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NWF24_07630	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
NWF24_07650	COG1228	amidohydrolase
NWF24_07655	COG4608	Belongs to the ABC transporter superfamily
NWF24_07660	COG0444	Belongs to the ABC transporter superfamily
NWF24_07665	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NWF24_07690	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NWF24_07695	COG4521	taurine ABC transporter
NWF24_07700	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
NWF24_07705	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NWF24_07710	COG0583	DNA-binding transcription factor activity
NWF24_07730	COG0284	orotidine-5'-phosphate decarboxylase activity
NWF24_07750	COG0366	Alpha amylase catalytic
NWF24_07910	COG3468	outer membrane autotransporter barrel domain protein
NWF24_07915	COG1280	lysine exporter protein (LysE YggA)
NWF24_07925	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NWF24_07950	COG1529	Aldehyde oxidase and xanthine dehydrogenase
NWF24_07950	COG2010	Cytochrome c
NWF24_07970	COG4106	trans-aconitate 2-methyltransferase activity
NWF24_07975	COG2771	luxR family
NWF24_07980	COG0477	Major facilitator Superfamily
NWF24_07985	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
NWF24_07990	COG1414	Transcriptional regulator
NWF24_08015	COG0318	PFAM AMP-dependent synthetase and ligase
NWF24_08020	COG1012	belongs to the aldehyde dehydrogenase family
NWF24_08045	COG1414	Transcriptional regulator
NWF24_08055	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NWF24_08060	COG0583	DNA-binding transcription factor activity
NWF24_08065	COG0243	molybdopterin cofactor binding
NWF24_08070	COG0437	4 iron, 4 sulfur cluster binding
NWF24_08075	COG3302	dmso reductase anchor subunit
NWF24_08085	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
NWF24_08105	COG1522	sequence-specific DNA binding
NWF24_08155	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
NWF24_08180	COG3209	COG3209 Rhs family protein
NWF24_08240	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
NWF24_08245	COG0308	aminopeptidase N
NWF24_08250	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NWF24_08260	COG1464	Belongs to the NlpA lipoprotein family
NWF24_08270	COG2011	ABC-type metal ion transport system permease component
NWF24_08290	COG1464	Belongs to the NlpA lipoprotein family
NWF24_08295	COG0583	DNA-binding transcription factor activity
NWF24_08300	COG0667	Aldo Keto reductase
NWF24_08305	COG2267	carboxylic ester hydrolase activity
NWF24_08310	COG0667	Aldo Keto reductase
NWF24_08320	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NWF24_08330	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
NWF24_08335	COG0251	oxidation-reduction process
NWF24_08345	COG1666	GTP binding
NWF24_08350	COG0812	UDP-N-acetylmuramate dehydrogenase activity
NWF24_08360	COG0137	argininosuccinate synthase activity
NWF24_08365	COG3123	guanosine phosphorylase activity
NWF24_08375	COG1393	Belongs to the ArsC family
NWF24_08380	COG0285	dihydrofolate synthase activity
NWF24_08405	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NWF24_08425	COG0583	DNA-binding transcription factor activity
NWF24_08435	COG0776	regulation of translation
NWF24_08470	COG1595	DNA-templated transcription, initiation
NWF24_08485	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
NWF24_08520	COG4774	siderophore transport
NWF24_08530	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NWF24_08550	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NWF24_08555	COG0577	efflux transmembrane transporter activity
NWF24_08555	COG1136	(ABC) transporter
NWF24_08560	COG1538	Outer membrane efflux protein
NWF24_08590	COG0277	FAD linked oxidase domain protein
NWF24_08600	COG1295	ribonuclease BN
NWF24_08610	COG3118	belongs to the thioredoxin family
NWF24_08620	COG0583	DNA-binding transcription factor activity
NWF24_08630	COG3181	Tripartite tricarboxylate transporter family receptor
NWF24_08635	COG2267	carboxylic ester hydrolase activity
NWF24_08660	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
NWF24_08665	COG0583	DNA-binding transcription factor activity
NWF24_08745	COG0583	DNA-binding transcription factor activity
NWF24_08750	COG1538	Outer membrane efflux protein
NWF24_08765	COG3265	gluconokinase activity
NWF24_08785	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NWF24_08795	COG0431	NADPH-dependent FMN reductase
NWF24_08805	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
NWF24_08825	COG3070	regulator of competence-specific genes
NWF24_08830	COG0346	lactoylglutathione lyase activity
NWF24_08840	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
NWF24_08845	COG0596	Alpha beta hydrolase
NWF24_08855	COG0625	glutathione transferase activity
NWF24_08875	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
NWF24_08880	COG2719	SpoVR family
NWF24_08885	COG2718	Belongs to the UPF0229 family
NWF24_08890	COG2766	serine protein kinase
NWF24_08895	COG0484	heat shock protein binding
NWF24_08900	COG0443	Heat shock 70 kDa protein
NWF24_08905	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NWF24_08920	COG0688	phosphatidylethanolamine metabolic process
NWF24_08930	COG2706	6-phosphogluconolactonase activity
NWF24_08940	COG1028	Short-chain dehydrogenase reductase Sdr
NWF24_08945	COG2721	sulfolactate sulfo-lyase activity
NWF24_08950	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
NWF24_08960	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
NWF24_08970	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NWF24_08975	COG2186	Transcriptional regulator
NWF24_08980	COG3181	Tripartite tricarboxylate transporter family receptor
NWF24_08985	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NWF24_08995	COG3181	Tripartite tricarboxylate transporter family receptor
NWF24_09005	COG1012	belongs to the aldehyde dehydrogenase family
NWF24_09025	COG1538	Outer membrane efflux protein
NWF24_09030	COG0842	Transport permease protein
NWF24_09035	COG0842	Transport permease protein
NWF24_09040	COG1131	(ABC) transporter
NWF24_09055	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NWF24_09065	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
NWF24_09075	COG1802	Transcriptional regulator
NWF24_09125	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NWF24_09130	COG1804	L-carnitine dehydratase bile acid-inducible protein F
NWF24_09145	COG2814	Major facilitator Superfamily
NWF24_09165	COG1959	2 iron, 2 sulfur cluster binding
NWF24_09165	COG1295	ribonuclease BN
NWF24_09180	COG0824	Thioesterase
NWF24_09190	COG3237	CsbD-like
NWF24_09195	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NWF24_09205	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NWF24_09230	COG1309	transcriptional regulator
NWF24_09235	COG1611	Belongs to the LOG family
NWF24_09240	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NWF24_09255	COG0596	Alpha beta hydrolase
NWF24_09260	COG0405	Gamma-glutamyltransferase
NWF24_09265	COG0322	excinuclease ABC activity
NWF24_09280	COG0583	DNA-binding transcription factor activity
NWF24_09285	COG0596	Alpha beta hydrolase
NWF24_09290	COG0473	3-isopropylmalate dehydrogenase activity
NWF24_09305	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
NWF24_09325	COG1881	PFAM PEBP family protein
NWF24_09345	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
NWF24_09350	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
NWF24_09365	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NWF24_09375	COG0670	Belongs to the BI1 family
NWF24_09380	COG3193	protein, possibly involved in utilization of glycolate and propanediol
NWF24_09410	COG3128	pkhd-type hydroxylase
NWF24_09415	COG4774	siderophore transport
NWF24_09420	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
NWF24_09425	COG1477	protein flavinylation
NWF24_09455	COG3634	alkyl hydroperoxide reductase activity
NWF24_09460	COG4771	TonB-dependent receptor
NWF24_09465	COG3720	iron ion transport
NWF24_09475	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NWF24_09480	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
NWF24_09485	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
NWF24_09500	COG0360	Binds together with S18 to 16S ribosomal RNA
NWF24_09505	COG2965	DNA replication, synthesis of RNA primer
NWF24_09510	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NWF24_09515	COG0359	binds to the 23S rRNA
NWF24_09520	COG0305	Participates in initiation and elongation during chromosome replication
NWF24_09550	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
NWF24_09555	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
NWF24_09565	COG0436	Aminotransferase
NWF24_09580	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
NWF24_09585	COG1763	Mo-molybdopterin cofactor biosynthetic process
NWF24_09590	COG0303	'Molybdopterin
NWF24_09595	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
NWF24_09600	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NWF24_09605	COG0314	molybdopterin synthase activity
NWF24_09610	COG3181	Tripartite tricarboxylate transporter family receptor
NWF24_09615	COG0542	response to heat
NWF24_09625	COG0183	Belongs to the thiolase family
NWF24_09645	COG0583	DNA-binding transcription factor activity
NWF24_09670	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
NWF24_09675	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NWF24_09705	COG3181	Tripartite tricarboxylate transporter family receptor
NWF24_09710	COG4974	Belongs to the 'phage' integrase family
NWF24_09725	COG0183	Belongs to the thiolase family
NWF24_09740	COG2833	Protein of unknown function (DUF455)
NWF24_09750	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
NWF24_09765	COG3201	nicotinamide mononucleotide transporter
NWF24_09770	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
NWF24_09775	COG0148	phosphopyruvate hydratase activity
NWF24_09785	COG0504	CTP synthase activity
NWF24_09790	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NWF24_09800	COG0756	dUTP diphosphatase activity
NWF24_09810	COG1047	Peptidyl-prolyl cis-trans
NWF24_09815	COG2850	peptidyl-arginine hydroxylation
NWF24_09830	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
NWF24_09835	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
NWF24_09840	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NWF24_09855	COG2814	Major facilitator Superfamily
NWF24_09865	COG0741	lytic transglycosylase activity
NWF24_09865	COG0739	heme binding
NWF24_09865	COG1196	nuclear chromosome segregation
NWF24_09910	COG0765	amino acid transport
NWF24_09915	COG0765	amino acid transport
NWF24_09920	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NWF24_09925	COG1126	abc transporter atp-binding protein
NWF24_09935	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NWF24_09945	COG1609	Transcriptional regulator
NWF24_09990	COG2197	response regulator
NWF24_09995	COG2205	protein histidine kinase activity
NWF24_09995	COG2202	Pas domain
NWF24_10010	COG2271	Major facilitator Superfamily
NWF24_10030	COG1305	Transglutaminase-like
NWF24_10055	COG1024	Enoyl-CoA hydratase
NWF24_10060	COG2308	Evidence 4 Homologs of previously reported genes of
NWF24_10075	COG2423	ornithine cyclodeaminase activity
NWF24_10085	COG2194	sulfuric ester hydrolase activity
NWF24_10090	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NWF24_10105	COG3842	ATPase activity
NWF24_10110	COG3842	ATPase activity
NWF24_10120	COG0395	ABC-type sugar transport system, permease component
NWF24_10140	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NWF24_10155	COG1131	(ABC) transporter
NWF24_10185	COG2951	lytic endotransglycosylase activity
NWF24_10200	COG0714	Associated with various cellular activities
NWF24_10210	COG1511	domain protein
NWF24_10210	COG3264	Mechanosensitive ion channel
NWF24_10220	COG1126	abc transporter atp-binding protein
NWF24_10225	COG0765	amino acid transport
NWF24_10245	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
NWF24_10265	COG1960	acyl-CoA dehydrogenase activity
NWF24_10280	COG4988	ABC transporter
NWF24_10285	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
NWF24_10290	COG1271	oxidase subunit
NWF24_10295	COG1294	oxidase, subunit
NWF24_10310	COG2226	methyltransferase
NWF24_10315	COG1216	Glycosyl transferase, family 2
NWF24_10315	COG0463	Glycosyl transferase, family 2
NWF24_10330	COG2226	methyltransferase
NWF24_10350	COG0318	PFAM AMP-dependent synthetase and ligase
NWF24_10360	COG2030	dehydratase
NWF24_10370	COG1028	Short-chain dehydrogenase reductase Sdr
NWF24_10375	COG1024	Enoyl-CoA hydratase
NWF24_10390	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NWF24_10395	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
NWF24_10400	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
NWF24_10415	COG0583	DNA-binding transcription factor activity
NWF24_10425	COG4032	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
NWF24_10425	COG0028	Belongs to the TPP enzyme family
NWF24_10430	COG1012	belongs to the aldehyde dehydrogenase family
NWF24_10440	COG2249	NAD(P)H dehydrogenase (quinone) activity
NWF24_10445	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NWF24_10460	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
NWF24_10470	COG1984	allophanate hydrolase subunit 2
NWF24_10480	COG0024	Methionine aminopeptidase
NWF24_10490	COG5002	protein histidine kinase activity
NWF24_10505	COG4585	Histidine kinase
NWF24_10520	COG3128	pkhd-type hydroxylase
NWF24_10525	COG4774	siderophore transport
NWF24_10540	COG0640	Transcriptional regulator
NWF24_10550	COG0477	Major facilitator Superfamily
NWF24_10560	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
NWF24_10570	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
NWF24_10665	COG0745	RESPONSE REGULATOR receiver
NWF24_10675	COG1414	Transcriptional regulator
NWF24_10680	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NWF24_10685	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NWF24_10700	COG2814	Major facilitator Superfamily
NWF24_10710	COG1082	Xylose isomerase domain protein TIM barrel
NWF24_10710	COG3185	4-Hydroxyphenylpyruvate dioxygenase
NWF24_10715	COG0477	Major facilitator Superfamily
NWF24_10745	COG3148	PFAM DTW domain containing protein
NWF24_10765	COG0251	oxidation-reduction process
NWF24_10775	COG2814	Major facilitator Superfamily
NWF24_10785	COG0154	amidase activity
NWF24_10790	COG0583	DNA-binding transcription factor activity
NWF24_10820	COG0583	DNA-binding transcription factor activity
NWF24_10840	COG3708	Transcriptional regulator
NWF24_10840	COG2207	Transcriptional regulator
NWF24_10845	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NWF24_10865	COG1309	transcriptional regulator
NWF24_10885	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NWF24_10885	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NWF24_10890	COG0509	glycine decarboxylation via glycine cleavage system
NWF24_10895	COG0404	The glycine cleavage system catalyzes the degradation of glycine
NWF24_10920	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
NWF24_10925	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NWF24_10960	COG1028	Short-chain dehydrogenase reductase Sdr
NWF24_10980	COG0642	Histidine kinase
NWF24_10985	COG0745	RESPONSE REGULATOR receiver
NWF24_10995	COG0671	phosphoesterase, PA-phosphatase related
NWF24_11015	COG4302	ethanolamine ammonia-lyase activity
NWF24_11020	COG4303	Ethanolamine ammonia lyase large subunit
NWF24_11025	COG0531	amino acid
NWF24_11030	COG0545	Peptidyl-prolyl cis-trans isomerase
NWF24_11035	COG1028	Short-chain dehydrogenase reductase Sdr
NWF24_11045	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
NWF24_11070	COG1804	L-carnitine dehydratase bile acid-inducible protein F
NWF24_11075	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NWF24_11085	COG3181	Tripartite tricarboxylate transporter family receptor
NWF24_11110	COG1804	L-carnitine dehydratase bile acid-inducible protein F
NWF24_11115	COG0436	Aminotransferase
NWF24_11135	COG1024	Enoyl-CoA hydratase
NWF24_11150	COG2223	nitrite transmembrane transporter activity
NWF24_11155	COG0583	DNA-binding transcription factor activity
NWF24_11170	COG0583	DNA-binding transcription factor activity
NWF24_11180	COG1396	sequence-specific DNA binding
NWF24_11180	COG3800	Transcriptional regulator
NWF24_11190	COG2818	Glycosylase
NWF24_11195	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NWF24_11200	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NWF24_11225	COG1183	phosphatidylcholine synthase activity
NWF24_11230	COG0518	GMP synthase (glutamine-hydrolyzing) activity
NWF24_11230	COG0519	Catalyzes the synthesis of GMP from XMP
NWF24_11255	COG1349	DNA-binding transcription factor activity
NWF24_11310	COG3781	membrane
NWF24_11315	COG1272	protein, Hemolysin III
NWF24_11325	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
NWF24_11330	COG0129	dihydroxy-acid dehydratase activity
NWF24_11340	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
NWF24_11345	COG1160	GTP binding
NWF24_11355	COG1309	transcriptional regulator
NWF24_11365	COG1132	(ABC) transporter
NWF24_11375	COG3384	dioxygenase
NWF24_11385	COG3038	cytochrome b561
NWF24_11425	COG0129	dihydroxy-acid dehydratase activity
NWF24_11455	COG0587	DNA-directed DNA polymerase activity
NWF24_11485	COG0583	DNA-binding transcription factor activity
NWF24_11535	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NWF24_11540	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NWF24_11545	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NWF24_11550	COG3181	Tripartite tricarboxylate transporter family receptor
NWF24_11555	COG1028	Short-chain dehydrogenase reductase Sdr
NWF24_11565	COG2267	carboxylic ester hydrolase activity
NWF24_11570	COG1414	Transcriptional regulator
NWF24_11575	COG1028	Short-chain dehydrogenase reductase Sdr
NWF24_11580	COG0028	Belongs to the TPP enzyme family
NWF24_11585	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
NWF24_11590	COG1012	belongs to the aldehyde dehydrogenase family
NWF24_11630	COG2271	Major facilitator Superfamily
NWF24_11675	COG3437	response regulator, receiver
NWF24_11680	COG2205	protein histidine kinase activity
NWF24_11680	COG0784	Response regulator, receiver
NWF24_11680	COG2198	Histidine kinase
NWF24_11700	COG3842	ATPase activity
NWF24_11725	COG0540	Belongs to the ATCase OTCase family
NWF24_11755	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
NWF24_11765	COG0235	Class ii aldolase
NWF24_11775	COG3976	FMN-binding domain protein
NWF24_11775	COG0431	NADPH-dependent FMN reductase
NWF24_11775	COG1053	succinate dehydrogenase
NWF24_11800	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NWF24_11810	COG0220	tRNA (guanine-N7-)-methyltransferase activity
NWF24_11815	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NWF24_11820	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
NWF24_11820	COG0493	'glutamate synthase
NWF24_11830	COG1741	Belongs to the pirin family
NWF24_11845	COG1741	Belongs to the pirin family
NWF24_11880	COG1054	Belongs to the UPF0176 family
NWF24_11900	COG0848	biopolymer transport protein
NWF24_11910	COG0824	Thioesterase
NWF24_11915	COG0436	Aminotransferase
NWF24_11920	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NWF24_11925	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
NWF24_11940	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NWF24_11940	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NWF24_11975	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NWF24_11980	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NWF24_11985	COG0741	lytic transglycosylase activity
NWF24_12005	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NWF24_12025	COG0215	cysteine-tRNA ligase activity
NWF24_12035	COG0825	malonyl-CoA metabolic process
NWF24_12040	COG0037	tRNA processing
NWF24_12045	COG0527	aspartate kinase activity
NWF24_12075	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NWF24_12100	COG2207	Transcriptional regulator
NWF24_12105	COG1960	acyl-CoA dehydrogenase activity
NWF24_12110	COG4585	Histidine kinase
NWF24_12120	COG2326	polyphosphate kinase activity
NWF24_12130	COG0642	Histidine kinase
NWF24_12160	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NWF24_12235	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
NWF24_12240	COG1011	Hydrolase
NWF24_12250	COG1280	lysine exporter protein (LysE YggA)
NWF24_12260	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
NWF24_12265	COG1562	ergosterol biosynthetic process
NWF24_12300	COG0544	peptidyl-prolyl cis-trans isomerase activity
NWF24_12305	COG0740	serine-type endopeptidase activity
NWF24_12310	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NWF24_12315	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
NWF24_12365	COG2113	Glycine betaine
NWF24_12370	COG4176	ABC-type proline glycine betaine transport system permease component
NWF24_12375	COG4175	Glycine betaine
NWF24_12380	COG0114	fumarate hydratase activity
NWF24_12385	COG2910	NAD(P)H-binding
NWF24_12390	COG0583	DNA-binding transcription factor activity
NWF24_12400	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NWF24_12410	COG4654	Cytochrome c, class I
NWF24_12425	COG0129	dihydroxy-acid dehydratase activity
NWF24_12430	COG0583	DNA-binding transcription factor activity
NWF24_12435	COG0583	DNA-binding transcription factor activity
NWF24_12440	COG1028	Short-chain dehydrogenase reductase Sdr
NWF24_12450	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NWF24_12455	COG1802	Transcriptional regulator
NWF24_12475	COG0318	PFAM AMP-dependent synthetase and ligase
NWF24_12485	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NWF24_12500	COG0730	response to heat
NWF24_12530	COG0038	chloride channel
NWF24_12540	COG1797	cobyrinic acid a,c-diamide synthase activity
NWF24_12560	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
NWF24_12565	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
NWF24_12570	COG0778	Nitroreductase
NWF24_12590	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
NWF24_12600	COG1380	Effector of murein hydrolase LrgA
NWF24_12605	COG1346	cytolysis
NWF24_12620	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
NWF24_12630	COG0657	acetylesterase activity
NWF24_12635	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NWF24_12645	COG1538	Outer membrane efflux protein
NWF24_12655	COG1492	cobalamin metabolic process
NWF24_12660	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
NWF24_12665	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
NWF24_12680	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NWF24_12685	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NWF24_12710	COG0560	Phosphoserine phosphatase
NWF24_12715	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NWF24_12720	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
NWF24_12720	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
NWF24_12725	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
NWF24_12725	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
NWF24_12750	COG1028	Short-chain dehydrogenase reductase Sdr
NWF24_12760	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NWF24_12775	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
NWF24_12780	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NWF24_12795	COG0557	exoribonuclease II activity
NWF24_12800	COG1028	Short-chain dehydrogenase reductase Sdr
NWF24_12805	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NWF24_12805	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
NWF24_12825	COG0052	Belongs to the universal ribosomal protein uS2 family
NWF24_12830	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NWF24_12835	COG0528	UMP kinase activity
NWF24_12840	COG0233	cytoplasmic translational termination
NWF24_12845	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NWF24_12850	COG0575	Belongs to the CDS family
NWF24_12855	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
NWF24_12860	COG0750	zinc metalloprotease
NWF24_12875	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NWF24_12880	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
NWF24_12885	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NWF24_12890	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NWF24_12895	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NWF24_12900	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NWF24_12905	COG0505	Belongs to the CarA family
NWF24_12910	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
NWF24_12920	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
NWF24_12935	COG1534	Rna-binding protein
NWF24_12940	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
NWF24_12945	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NWF24_12955	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NWF24_12975	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NWF24_12980	COG1024	Enoyl-CoA hydratase
NWF24_12985	COG1250	3-hydroxyacyl-CoA dehydrogenase
NWF24_12990	COG2814	Major facilitator Superfamily
NWF24_12995	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
NWF24_13005	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NWF24_13010	COG0252	asparaginase activity
NWF24_13015	COG0563	adenylate kinase activity
NWF24_13020	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
NWF24_13025	COG2835	tetraacyldisaccharide 4'-kinase activity
NWF24_13030	COG1663	tetraacyldisaccharide 4'-kinase activity
NWF24_13035	COG0848	biopolymer transport protein
NWF24_13040	COG0811	peptide transport
NWF24_13045	COG1570	exodeoxyribonuclease VII activity
NWF24_13050	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
NWF24_13075	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
NWF24_13080	COG0542	response to heat
NWF24_13085	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NWF24_13090	COG2925	Exonuclease
NWF24_13140	COG0402	S-adenosylhomocysteine deaminase activity
NWF24_13150	COG1079	Belongs to the binding-protein-dependent transport system permease family
NWF24_13155	COG4603	Belongs to the binding-protein-dependent transport system permease family
NWF24_13160	COG3845	ABC transporter
NWF24_13165	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NWF24_13170	COG1744	ABC transporter substrate-binding protein PnrA-like
NWF24_13175	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NWF24_13195	COG1595	DNA-templated transcription, initiation
NWF24_13215	COG0433	COG0433 Predicted ATPase
NWF24_13230	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
NWF24_13280	COG3550	peptidyl-serine autophosphorylation
NWF24_13295	COG1196	nuclear chromosome segregation
NWF24_13305	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NWF24_13315	COG0242	peptide deformylase activity
NWF24_13320	COG2259	Doxx family
NWF24_13325	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NWF24_13330	COG4597	amino acid ABC transporter
NWF24_13335	COG0765	amino acid transport
NWF24_13345	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NWF24_13355	COG1396	sequence-specific DNA binding
NWF24_13365	COG0667	Aldo Keto reductase
NWF24_13395	COG0457	Tetratricopeptide repeat
NWF24_13400	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
NWF24_13405	COG1215	transferase activity, transferring glycosyl groups
NWF24_13410	COG1215	transferase activity, transferring glycosyl groups
NWF24_13430	COG2199	diguanylate cyclase activity
NWF24_13430	COG2203	Gaf domain
NWF24_13435	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
NWF24_13440	COG0024	Methionine aminopeptidase
NWF24_13445	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NWF24_13445	COG0047	phosphoribosylformylglycinamidine synthase activity
NWF24_13450	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
NWF24_13460	COG2917	probably involved in intracellular septation
NWF24_13465	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NWF24_13470	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
NWF24_13480	COG2272	Belongs to the type-B carboxylesterase lipase family
NWF24_13485	COG0318	PFAM AMP-dependent synthetase and ligase
NWF24_13500	COG0559	Belongs to the binding-protein-dependent transport system permease family
NWF24_13510	COG0411	ABC transporter
NWF24_13520	COG1250	3-hydroxyacyl-CoA dehydrogenase
NWF24_13520	COG1024	Enoyl-CoA hydratase
NWF24_13525	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NWF24_13530	COG0183	Belongs to the thiolase family
NWF24_13540	COG1960	acyl-CoA dehydrogenase activity
NWF24_13565	COG2130	NADP-dependent
NWF24_13570	COG1960	acyl-CoA dehydrogenase activity
NWF24_13595	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NWF24_13600	COG0583	DNA-binding transcription factor activity
NWF24_13650	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NWF24_13660	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
NWF24_13670	COG0640	Transcriptional regulator
NWF24_13675	COG5001	Diguanylate cyclase
NWF24_13675	COG3300	MHYT domain
NWF24_13685	COG2814	Major facilitator Superfamily
NWF24_13690	COG0583	DNA-binding transcription factor activity
NWF24_13715	COG0247	lactate metabolic process
NWF24_13715	COG0277	FAD linked oxidase domain protein
NWF24_13720	COG0477	Major facilitator Superfamily
NWF24_13730	COG1864	DNA RNA non-specific endonuclease
NWF24_13730	COG3591	Belongs to the peptidase S1B family
NWF24_13740	COG0583	DNA-binding transcription factor activity
NWF24_13750	COG0583	DNA-binding transcription factor activity
NWF24_13780	COG1028	Short-chain dehydrogenase reductase Sdr
NWF24_13790	COG2814	Major facilitator Superfamily
NWF24_13795	COG2814	Major facilitator Superfamily
NWF24_13800	COG2995	paraquat-inducible protein a
NWF24_13805	COG2995	paraquat-inducible protein a
NWF24_13810	COG3008	intermembrane lipid transfer
NWF24_13810	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
NWF24_13820	COG0477	Major facilitator Superfamily
NWF24_13845	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
NWF24_13845	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
NWF24_13850	COG1609	Transcriptional regulator
NWF24_13855	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
NWF24_13860	COG3618	amidohydrolase
NWF24_13880	COG0534	Mate efflux family protein
NWF24_13915	COG2201	protein-glutamate methylesterase activity
NWF24_13925	COG2183	response to ionizing radiation
NWF24_13945	COG1538	Outer membrane efflux protein
NWF24_13960	COG0745	RESPONSE REGULATOR receiver
NWF24_13980	COG0443	Heat shock 70 kDa protein
NWF24_14035	COG2153	protein acetylation
NWF24_14050	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NWF24_14055	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NWF24_14070	COG0084	hydrolase, TatD family'
NWF24_14075	COG0666	response to abiotic stimulus
NWF24_14205	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NWF24_14215	COG1309	transcriptional regulator
NWF24_14250	COG2358	TRAP transporter, solute receptor (TAXI family
NWF24_14255	COG1309	transcriptional regulator
NWF24_14310	COG3181	Tripartite tricarboxylate transporter family receptor
NWF24_14320	COG2084	Dehydrogenase
NWF24_14330	COG0583	DNA-binding transcription factor activity
NWF24_14335	COG0583	DNA-binding transcription factor activity
NWF24_14350	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
NWF24_14365	COG1028	Short-chain dehydrogenase reductase Sdr
NWF24_14385	COG0583	DNA-binding transcription factor activity
NWF24_14405	COG3618	amidohydrolase
NWF24_14410	COG3181	Tripartite tricarboxylate transporter family receptor
NWF24_14415	COG1012	belongs to the aldehyde dehydrogenase family
NWF24_14415	COG2030	dehydratase
NWF24_14430	COG1250	3-hydroxyacyl-CoA dehydrogenase
NWF24_14435	COG1250	3-hydroxyacyl-CoA dehydrogenase
NWF24_14440	COG1960	acyl-CoA dehydrogenase activity
NWF24_14445	COG1028	Short-chain dehydrogenase reductase Sdr
NWF24_14450	COG1024	Enoyl-CoA hydratase
NWF24_14460	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
NWF24_14465	COG1804	L-carnitine dehydratase bile acid-inducible protein F
NWF24_14470	COG3290	protein histidine kinase activity
NWF24_14470	COG3829	transcription factor binding
NWF24_14475	COG1804	L-carnitine dehydratase bile acid-inducible protein F
NWF24_14485	COG1028	Short-chain dehydrogenase reductase Sdr
NWF24_14525	COG0463	Glycosyl transferase, family 2
NWF24_14535	COG0642	Histidine kinase
NWF24_14545	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
NWF24_14555	COG1529	Aldehyde oxidase and xanthine dehydrogenase
NWF24_14560	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
NWF24_14565	COG2080	2 iron, 2 sulfur cluster binding
NWF24_14610	COG1064	alcohol dehydrogenase
NWF24_14620	COG4221	oxidoreductase activity
NWF24_14655	COG0583	DNA-binding transcription factor activity
NWF24_14660	COG0583	DNA-binding transcription factor activity
NWF24_14665	COG4948	Mandelate Racemase Muconate Lactonizing
NWF24_14670	COG3181	Tripartite tricarboxylate transporter family receptor
NWF24_14675	COG3181	Tripartite tricarboxylate transporter family receptor
NWF24_14705	COG1136	(ABC) transporter
NWF24_14705	COG0577	efflux transmembrane transporter activity
NWF24_14710	COG1136	(ABC) transporter
NWF24_14710	COG0577	efflux transmembrane transporter activity
NWF24_14730	COG0655	NAD(P)H dehydrogenase (quinone) activity
NWF24_14740	COG1574	metal-dependent hydrolase with the TIM-barrel fold
NWF24_14750	COG0583	DNA-binding transcription factor activity
NWF24_14765	COG0583	DNA-binding transcription factor activity
NWF24_14775	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
NWF24_14780	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NWF24_14785	COG0066	3-isopropylmalate dehydratase activity
NWF24_14800	COG1012	belongs to the aldehyde dehydrogenase family
NWF24_14805	COG4993	Dehydrogenase
NWF24_14890	COG3181	Tripartite tricarboxylate transporter family receptor
NWF24_14895	COG0583	DNA-binding transcription factor activity
NWF24_14905	COG0596	Alpha beta hydrolase
NWF24_14905	COG0508	dehydrogenase complex catalyzes the overall conversion of
NWF24_14920	COG3181	Tripartite tricarboxylate transporter family receptor
NWF24_14925	COG0006	proline dipeptidase activity
NWF24_14935	COG2207	Transcriptional regulator
NWF24_14970	COG2084	Dehydrogenase
NWF24_14980	COG3181	Tripartite tricarboxylate transporter family receptor
NWF24_14990	COG1024	Enoyl-CoA hydratase
NWF24_14995	COG1960	acyl-CoA dehydrogenase activity
NWF24_15000	COG1024	Enoyl-CoA hydratase
NWF24_15005	COG1028	Short-chain dehydrogenase reductase Sdr
NWF24_15010	COG1250	3-hydroxyacyl-CoA dehydrogenase
NWF24_15015	COG0183	Belongs to the thiolase family
NWF24_15025	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
NWF24_15110	COG0589	response to stress
NWF24_15120	COG1063	alcohol dehydrogenase
NWF24_15165	COG2197	response regulator
NWF24_15175	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
NWF24_15185	COG4191	Histidine kinase
NWF24_15185	COG0784	Response regulator, receiver
NWF24_15195	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NWF24_15210	COG4716	Myosin-crossreactive antigen
NWF24_15240	COG0635	Involved in the biosynthesis of porphyrin-containing compound
NWF24_15275	COG3278	Belongs to the heme-copper respiratory oxidase family
NWF24_15285	COG2217	Heavy metal translocating P-type atpase
NWF24_15295	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NWF24_15310	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NWF24_15340	COG1172	Belongs to the binding-protein-dependent transport system permease family
NWF24_15360	COG0431	NADPH-dependent FMN reductase
NWF24_15370	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NWF24_15380	COG3829	transcription factor binding
NWF24_15390	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
NWF24_15395	COG3616	Alanine racemase, N-terminal domain
NWF24_15405	COG0583	DNA-binding transcription factor activity
NWF24_15445	COG2197	response regulator
NWF24_15500	COG4964	Belongs to the GSP D family
NWF24_15545	COG0420	3'-5' exonuclease activity
NWF24_15595	COG0489	protein tyrosine kinase activity
NWF24_15595	COG3206	protein involved in exopolysaccharide biosynthesis
NWF24_15605	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NWF24_15635	COG0297	glycogen (starch) synthase activity
NWF24_15640	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
NWF24_15645	COG2197	response regulator
NWF24_15660	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NWF24_15670	COG1028	Short-chain dehydrogenase reductase Sdr
NWF24_15695	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
NWF24_15705	COG1116	anion transmembrane transporter activity
NWF24_15715	COG3360	Dodecin
NWF24_15725	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NWF24_15730	COG0045	succinate-CoA ligase (ADP-forming) activity
NWF24_15730	COG1042	CoA-binding domain protein
NWF24_15730	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NWF24_15755	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NWF24_15765	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NWF24_15785	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NWF24_15790	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NWF24_15810	COG0667	Aldo Keto reductase
NWF24_15825	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NWF24_15840	COG2814	Major facilitator Superfamily
NWF24_15855	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
NWF24_15860	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NWF24_15865	COG2207	Transcriptional regulator
NWF24_15870	COG0667	Aldo Keto reductase
NWF24_15875	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
NWF24_15880	COG0156	8-amino-7-oxononanoate synthase activity
NWF24_15930	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
NWF24_15930	COG1199	ATP-dependent helicase activity
NWF24_15940	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
NWF24_15950	COG5002	protein histidine kinase activity
NWF24_15955	COG0745	RESPONSE REGULATOR receiver
NWF24_15960	COG1028	Short-chain dehydrogenase reductase Sdr
NWF24_15965	COG0667	Aldo Keto reductase
NWF24_15970	COG0667	Aldo Keto reductase
NWF24_16010	COG1619	proteins homologs of microcin C7 resistance protein MccF
NWF24_16040	COG4566	intracellular signal transduction
NWF24_16045	COG4191	Histidine kinase
NWF24_16105	COG2207	Transcriptional regulator
NWF24_16110	COG0518	GMP synthase (glutamine-hydrolyzing) activity
NWF24_16110	COG0519	Catalyzes the synthesis of GMP from XMP
NWF24_16135	COG2914	Belongs to the UPF0125 (RnfH) family
NWF24_16140	COG2867	negative regulation of translational initiation
NWF24_16145	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
NWF24_16185	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NWF24_16190	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NWF24_16195	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NWF24_16200	COG0195	Participates in both transcription termination and antitermination
NWF24_16200	COG2251	uridine kinase activity
NWF24_16205	COG0779	Required for maturation of 30S ribosomal subunits
NWF24_16210	COG0477	Major facilitator Superfamily
NWF24_16215	COG4172	Belongs to the ABC transporter superfamily
NWF24_16220	COG4239	(ABC) transporter, permease
NWF24_16225	COG4174	ABC transporter (Permease)
NWF24_16230	COG4166	transmembrane transport
NWF24_16240	COG1793	dna ligase
NWF24_16290	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
NWF24_16300	COG0795	lipopolysaccharide-transporting ATPase activity
NWF24_16310	COG0583	DNA-binding transcription factor activity
NWF24_16315	COG0436	Aminotransferase
NWF24_16330	COG1643	Atp-dependent helicase
NWF24_16335	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NWF24_16340	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
NWF24_16340	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
NWF24_16345	COG1280	lysine exporter protein (LysE YggA)
NWF24_16355	COG2171	N-acyltransferase activity
NWF24_16365	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NWF24_16370	COG2890	protein-(glutamine-N5) methyltransferase activity
NWF24_16375	COG0488	(ABC) transporter
NWF24_16395	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
NWF24_16405	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NWF24_16410	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NWF24_16430	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
NWF24_16440	COG2885	chlorophyll binding
NWF24_16445	COG0823	Involved in the tonB-independent uptake of proteins
NWF24_16450	COG1132	(ABC) transporter
NWF24_16455	COG1530	ribonuclease E activity
NWF24_16460	COG0424	maF-like protein
NWF24_16470	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NWF24_16475	COG0799	negative regulation of ribosome biogenesis
NWF24_16480	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NWF24_16485	COG0408	coproporphyrinogen oxidase activity
NWF24_16490	COG0151	Belongs to the GarS family
NWF24_16495	COG0217	transcriptional regulatory protein
NWF24_16500	COG2226	methyltransferase
NWF24_16505	COG0251	oxidation-reduction process
NWF24_16520	COG1538	Outer membrane efflux protein
NWF24_16530	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NWF24_16540	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
NWF24_16545	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
NWF24_16550	COG4208	sulfate ABC transporter
NWF24_16560	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
NWF24_16570	COG0450	alkyl hydroperoxide reductase
NWF24_16580	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NWF24_16595	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NWF24_16615	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NWF24_16620	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NWF24_16630	COG1045	serine acetyltransferase
NWF24_16645	COG1116	anion transmembrane transporter activity
NWF24_16650	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NWF24_16655	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NWF24_16660	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NWF24_16690	COG0778	Nitroreductase
NWF24_16700	COG1116	anion transmembrane transporter activity
NWF24_16705	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
NWF24_16710	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NWF24_16715	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NWF24_16720	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
NWF24_16730	COG0431	NADPH-dependent FMN reductase
NWF24_16740	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
NWF24_16745	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
NWF24_16745	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NWF24_16760	COG0584	glycerophosphoryl diester phosphodiesterase
NWF24_16770	COG5002	protein histidine kinase activity
NWF24_16775	COG0745	RESPONSE REGULATOR receiver
NWF24_16780	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
NWF24_16785	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
NWF24_16795	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NWF24_16800	COG0427	acetyl-CoA hydrolase
NWF24_16805	COG3588	fructose-bisphosphate aldolase
NWF24_16820	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NWF24_16830	COG0667	Aldo Keto reductase
NWF24_16850	COG2382	esterase
NWF24_16875	COG2205	protein histidine kinase activity
NWF24_16885	COG1446	asparaginase
NWF24_16890	COG4172	Belongs to the ABC transporter superfamily
NWF24_16900	COG0601	transmembrane transport
NWF24_16905	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NWF24_16915	COG2362	D-Aminopeptidase
NWF24_16930	COG0175	sulfate reduction
NWF24_16945	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
NWF24_16950	COG0492	ferredoxin-NADP+ reductase activity
NWF24_16965	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
NWF24_16975	COG0351	phosphomethylpyrimidine kinase
NWF24_16990	COG2022	thiamine diphosphate biosynthetic process
NWF24_17015	COG3468	outer membrane autotransporter barrel domain protein
NWF24_17020	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
NWF24_17030	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
NWF24_17070	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NWF24_17085	COG1414	Transcriptional regulator
NWF24_17115	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
NWF24_17120	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
NWF24_17125	COG1414	Transcriptional regulator
NWF24_17135	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NWF24_17140	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NWF24_17145	COG1183	phosphatidylcholine synthase activity
NWF24_17150	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
NWF24_17160	COG0440	acetolactate synthase activity
NWF24_17165	COG0028	Belongs to the TPP enzyme family
NWF24_17190	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
NWF24_17225	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
NWF24_17250	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NWF24_17310	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NWF24_17320	COG1012	belongs to the aldehyde dehydrogenase family
NWF24_17345	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
NWF24_17350	COG0746	molybdenum cofactor guanylyltransferase activity
NWF24_17355	COG0303	'Molybdopterin
NWF24_17360	COG0328	RNA-DNA hybrid ribonuclease activity
NWF24_17370	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NWF24_17375	COG1388	LysM domain
NWF24_17375	COG0741	lytic transglycosylase activity
NWF24_17385	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NWF24_17395	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
NWF24_17400	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NWF24_17405	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
NWF24_17410	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NWF24_17440	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
NWF24_17445	COG0673	inositol 2-dehydrogenase activity
NWF24_17450	COG0254	rRNA binding
NWF24_17460	COG0534	Mate efflux family protein
NWF24_17480	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
NWF24_17485	COG0581	inorganic phosphate transmembrane transporter activity
NWF24_17490	COG0573	inorganic phosphate transmembrane transporter activity
NWF24_17495	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
NWF24_17500	COG0248	Ppx GppA phosphatase
NWF24_17520	COG0492	ferredoxin-NADP+ reductase activity
NWF24_17530	COG0625	glutathione transferase activity
NWF24_17545	COG0582	viral genome integration into host DNA
NWF24_17610	COG1196	nuclear chromosome segregation
NWF24_17665	COG0740	serine-type endopeptidase activity
NWF24_17840	COG3561	AntA/AntB antirepressor
NWF24_17925	COG2188	Transcriptional regulator
NWF24_17930	COG0683	leucine binding
NWF24_17955	COG3181	Tripartite tricarboxylate transporter family receptor
NWF24_17960	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NWF24_17965	COG0066	3-isopropylmalate dehydratase activity
NWF24_18065	COG0745	RESPONSE REGULATOR receiver
NWF24_18070	COG2205	protein histidine kinase activity
NWF24_18075	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
NWF24_18100	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
NWF24_18120	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NWF24_18130	COG0114	fumarate hydratase activity
NWF24_18140	COG0783	Belongs to the Dps family
NWF24_18150	COG0363	glucosamine-6-phosphate deaminase activity
NWF24_18195	COG0179	Fumarylacetoacetate (FAA) hydrolase
NWF24_18220	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NWF24_18240	COG0765	amino acid transport
NWF24_18265	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NWF24_18275	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
NWF24_18285	COG1473	amidohydrolase
NWF24_18290	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
NWF24_18295	COG1984	allophanate hydrolase subunit 2
NWF24_18300	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
NWF24_18305	COG0583	DNA-binding transcription factor activity
NWF24_18310	COG4336	lyase activity
NWF24_18355	COG1028	Short-chain dehydrogenase reductase Sdr
NWF24_18410	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NWF24_18450	COG0596	Alpha beta hydrolase
NWF24_18455	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NWF24_18460	COG1028	Short-chain dehydrogenase reductase Sdr
NWF24_18465	COG2186	Transcriptional regulator
NWF24_18475	COG0235	Class ii aldolase
NWF24_18480	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NWF24_18515	COG1137	ATPase activity
NWF24_18520	COG0559	Belongs to the binding-protein-dependent transport system permease family
NWF24_18530	COG0179	Fumarylacetoacetate (FAA) hydrolase
NWF24_18565	COG1024	Enoyl-CoA hydratase
NWF24_18580	COG1522	sequence-specific DNA binding
NWF24_18585	COG1028	Short-chain dehydrogenase reductase Sdr
NWF24_18590	COG1804	L-carnitine dehydratase bile acid-inducible protein F
NWF24_18615	COG3706	GGDEF domain
NWF24_18625	COG1846	Transcriptional regulator
NWF24_18625	COG0456	acetyltransferase
NWF24_18630	COG1028	Short-chain dehydrogenase reductase Sdr
NWF24_18635	COG4689	acetoacetate decarboxylase
NWF24_18655	COG1295	ribonuclease BN
NWF24_18665	COG2059	Chromate
NWF24_18670	COG0667	Aldo Keto reductase
NWF24_18700	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NWF24_18715	COG1136	(ABC) transporter
NWF24_18730	COG0626	cystathionine gamma-synthase activity
NWF24_18750	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NWF24_18755	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
NWF24_18765	COG0330	HflC and HflK could
NWF24_18770	COG0330	HflC and HflK could
NWF24_18775	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NWF24_18780	COG1923	regulation of RNA biosynthetic process
NWF24_18785	COG1160	GTP binding
NWF24_18800	COG0124	histidyl-tRNA synthetase
NWF24_18805	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
NWF24_18820	COG0820	rRNA (adenine-C2-)-methyltransferase activity
NWF24_18825	COG0105	UTP biosynthetic process
NWF24_18830	COG1187	pseudouridine synthase activity
NWF24_18835	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NWF24_18840	COG0564	pseudouridine synthase activity
NWF24_18850	COG1199	ATP-dependent helicase activity
NWF24_18870	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
NWF24_18875	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NWF24_18880	COG0508	dehydrogenase complex catalyzes the overall conversion of
NWF24_18885	COG0567	Dehydrogenase, E1 component
NWF24_18905	COG2368	4-hydroxyphenylacetate
NWF24_18915	COG2133	pyrroloquinoline quinone binding
NWF24_18920	COG0791	NLP P60 protein
NWF24_18925	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NWF24_18930	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
NWF24_18935	COG0508	dehydrogenase complex catalyzes the overall conversion of
NWF24_18940	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
NWF24_18950	COG4566	intracellular signal transduction
NWF24_18955	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NWF24_18970	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
NWF24_18975	COG0167	dihydroorotate dehydrogenase activity
NWF24_18990	COG0579	oxidoreductase
NWF24_19005	COG0633	Ferredoxin
NWF24_19010	COG0443	Heat shock 70 kDa protein
NWF24_19025	COG0822	iron-sulfur transferase activity
NWF24_19030	COG1104	cysteine desulfurase activity
NWF24_19035	COG1959	2 iron, 2 sulfur cluster binding
NWF24_19040	COG0556	nucleotide-excision repair
NWF24_19055	COG2878	Part of a membrane complex involved in electron transport
NWF24_19065	COG0697	spore germination
NWF24_19070	COG1522	sequence-specific DNA binding
NWF24_19080	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
NWF24_19085	COG4770	biotin carboxylase activity
NWF24_19090	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
NWF24_19095	COG1703	isobutyryl-CoA mutase activity
NWF24_19105	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
NWF24_19105	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
NWF24_19110	COG1802	Transcriptional regulator
NWF24_19115	COG1309	transcriptional regulator
NWF24_19155	COG1640	4-alpha-glucanotransferase
NWF24_19160	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
NWF24_19175	COG0366	Alpha amylase catalytic
NWF24_19180	COG0366	Alpha amylase catalytic
NWF24_19185	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
NWF24_19235	COG0300	oxidoreductase activity
NWF24_19245	COG0583	DNA-binding transcription factor activity
NWF24_19275	COG0477	Major facilitator Superfamily
NWF24_19290	COG0025	NhaP-type Na H and K H
NWF24_19295	COG0028	Belongs to the TPP enzyme family
NWF24_19310	COG4585	Histidine kinase
NWF24_19315	COG0583	DNA-binding transcription factor activity
NWF24_19320	COG2249	NAD(P)H dehydrogenase (quinone) activity
NWF24_19345	COG0583	DNA-binding transcription factor activity
NWF24_19360	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
NWF24_19380	COG1733	regulation of RNA biosynthetic process
NWF24_19420	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NWF24_19430	COG1793	dna ligase
NWF24_19460	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NWF24_19505	COG4774	siderophore transport
NWF24_19520	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
NWF24_19520	COG4651	solute:proton antiporter activity
NWF24_19525	COG1301	dicarboxylic acid transport
NWF24_19530	COG1028	Short-chain dehydrogenase reductase Sdr
NWF24_19540	COG1058	Belongs to the CinA family
NWF24_19540	COG1546	Belongs to the CinA family
NWF24_19560	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
NWF24_19570	COG0583	DNA-binding transcription factor activity
NWF24_19580	COG0625	glutathione transferase activity
NWF24_19590	COG0183	Belongs to the thiolase family
NWF24_19595	COG3243	poly(R)-hydroxyalkanoic acid synthase
NWF24_19630	COG3045	CreA protein
NWF24_19645	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NWF24_19660	COG1132	(ABC) transporter
NWF24_19670	COG2831	hemolysin activation secretion protein
NWF24_19680	COG3210	domain, Protein
NWF24_19705	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NWF24_19710	COG2877	3-deoxy-8-phosphooctulonate synthase activity
NWF24_19715	COG0840	transmembrane signaling receptor activity
NWF24_19745	COG0583	DNA-binding transcription factor activity
NWF24_19750	COG2159	amidohydrolase
NWF24_19760	COG3384	dioxygenase
NWF24_19770	COG3181	Tripartite tricarboxylate transporter family receptor
NWF24_19775	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
NWF24_19790	COG0583	DNA-binding transcription factor activity
NWF24_19805	COG1804	L-carnitine dehydratase bile acid-inducible protein F
NWF24_19830	COG0596	Alpha beta hydrolase
NWF24_19840	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NWF24_19840	COG0785	Cytochrome C biogenesis protein
NWF24_19855	COG0582	viral genome integration into host DNA
NWF24_19895	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
NWF24_19900	COG1061	Type III restriction enzyme res subunit
NWF24_19905	COG1002	Type II restriction enzyme, methylase subunits
NWF24_19930	COG1295	ribonuclease BN
NWF24_19935	COG0583	DNA-binding transcription factor activity
NWF24_19940	COG0300	oxidoreductase activity
NWF24_19945	COG1028	Short-chain dehydrogenase reductase Sdr
NWF24_19955	COG4221	oxidoreductase activity
NWF24_19970	COG2175	clavaminate synthase activity
NWF24_19985	COG0747	negative chemotaxis
NWF24_19995	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NWF24_20000	COG0444	Belongs to the ABC transporter superfamily
NWF24_20010	COG4608	Belongs to the ABC transporter superfamily
NWF24_20025	COG3181	Tripartite tricarboxylate transporter family receptor
NWF24_20030	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NWF24_20070	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NWF24_20095	COG0154	amidase activity
NWF24_20135	COG2814	Major facilitator Superfamily
NWF24_20145	COG4221	oxidoreductase activity
NWF24_20160	COG1012	belongs to the aldehyde dehydrogenase family
NWF24_20170	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
NWF24_20175	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NWF24_20175	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NWF24_20180	COG0277	FAD linked oxidase domain protein
NWF24_20210	COG0683	leucine binding
NWF24_20215	COG0559	Belongs to the binding-protein-dependent transport system permease family
NWF24_20330	COG0776	regulation of translation
NWF24_20335	COG0072	phenylalanine-tRNA ligase activity
NWF24_20335	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NWF24_20340	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NWF24_20345	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NWF24_20350	COG0291	Belongs to the bacterial ribosomal protein bL35 family
NWF24_20355	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NWF24_20360	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NWF24_20395	COG2207	Transcriptional regulator
NWF24_20405	COG0028	Belongs to the TPP enzyme family
NWF24_20410	COG1309	transcriptional regulator
NWF24_20420	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NWF24_20425	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
NWF24_20440	COG0673	inositol 2-dehydrogenase activity
NWF24_20470	COG3214	Protein conserved in bacteria
NWF24_20475	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
NWF24_20490	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
NWF24_20495	COG0802	atpase or kinase
NWF24_20500	COG0860	N-Acetylmuramoyl-L-alanine amidase
NWF24_20510	COG0586	Pfam SNARE associated Golgi protein
NWF24_20525	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NWF24_20550	COG1028	Short-chain dehydrogenase reductase Sdr
NWF24_20555	COG2207	Transcriptional regulator
NWF24_20560	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NWF24_20565	COG4181	ATPase activity
NWF24_20575	COG2186	Transcriptional regulator
NWF24_20590	COG3795	YCII-related domain
NWF24_20595	COG4941	Belongs to the sigma-70 factor family
NWF24_20600	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
NWF24_20675	COG1566	PFAM secretion protein HlyD family protein
NWF24_20680	COG1538	Outer membrane efflux protein
NWF24_20685	COG1846	Transcriptional regulator
NWF24_20690	COG1132	(ABC) transporter
NWF24_20700	COG0494	nUDIX hydrolase
NWF24_20710	COG1007	ATP synthesis coupled electron transport
NWF24_20725	COG0713	ATP synthesis coupled electron transport
NWF24_20735	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NWF24_20740	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
NWF24_20745	COG1034	ATP synthesis coupled electron transport
NWF24_20760	COG0649	NAD binding
NWF24_20765	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NWF24_20770	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NWF24_20775	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NWF24_20790	COG0149	triose-phosphate isomerase activity
NWF24_20795	COG0604	alcohol dehydrogenase
NWF24_20795	COG1028	Short-chain dehydrogenase reductase Sdr
NWF24_20795	COG3321	synthase
NWF24_20800	COG1185	polyribonucleotide nucleotidyltransferase activity
NWF24_20805	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NWF24_20810	COG0697	spore germination
NWF24_20815	COG0436	Aminotransferase
NWF24_20820	COG0683	leucine binding
NWF24_20835	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NWF24_20840	COG3707	response regulator
NWF24_20845	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
NWF24_20850	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NWF24_20855	COG1116	anion transmembrane transporter activity
NWF24_20865	COG2223	nitrite transmembrane transporter activity
NWF24_20870	COG0515	serine threonine protein kinase
NWF24_20870	COG2815	serine threonine protein kinase
NWF24_20875	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NWF24_20890	COG0243	molybdopterin cofactor binding
NWF24_20895	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NWF24_20915	COG1176	ABC-type spermidine putrescine transport system, permease component I
NWF24_20920	COG3833	ABC-type maltose transport systems, permease component
NWF24_20935	COG2081	HI0933 family
NWF24_20940	COG0828	Belongs to the bacterial ribosomal protein bS21 family
NWF24_20950	COG0494	nUDIX hydrolase
NWF24_20965	COG1063	alcohol dehydrogenase
NWF24_20970	COG3842	ATPase activity
NWF24_20975	COG0395	ABC-type sugar transport system, permease component
NWF24_20980	COG1175	transmembrane transport
NWF24_20985	COG1653	transport
NWF24_20995	COG2814	Major facilitator Superfamily
NWF24_21005	COG0312	modulator of DNA gyrase
NWF24_21010	COG3028	Belongs to the UPF0307 family
NWF24_21015	COG0521	Mo-molybdopterin cofactor biosynthetic process
NWF24_21060	COG0642	Histidine kinase
NWF24_21065	COG0475	glutathione-regulated potassium exporter activity
NWF24_21085	COG0789	Transcriptional regulator
NWF24_21090	COG1045	serine acetyltransferase
NWF24_21100	COG0483	inositol monophosphate 1-phosphatase activity
NWF24_21105	COG1289	transmembrane transporter activity
NWF24_21115	COG2832	Protein of unknown function (DUF454)
NWF24_21120	COG2311	Membrane
NWF24_21135	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
NWF24_21145	COG0583	DNA-binding transcription factor activity
NWF24_21160	COG3119	arylsulfatase activity
NWF24_21190	COG0820	rRNA (adenine-C2-)-methyltransferase activity
NWF24_21200	COG2207	Transcriptional regulator
NWF24_21225	COG1733	regulation of RNA biosynthetic process
NWF24_21245	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
NWF24_21295	COG1846	Transcriptional regulator
NWF24_21310	COG2375	cellular response to nickel ion
NWF24_21325	COG0598	Magnesium transport protein CorA
NWF24_21335	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NWF24_21370	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NWF24_21375	COG0601	transmembrane transport
NWF24_21380	COG0747	negative chemotaxis
NWF24_21385	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NWF24_21390	COG3795	YCII-related domain
NWF24_21405	COG4585	Histidine kinase
NWF24_21425	COG1968	undecaprenyl-diphosphatase activity
NWF24_21440	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NWF24_21445	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
NWF24_21450	COG1737	Transcriptional regulator
NWF24_21465	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
NWF24_21510	COG3275	phosphorelay sensor kinase activity
NWF24_21525	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NWF24_21560	COG0004	ammonium transporteR
NWF24_21590	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
NWF24_21600	COG0517	IMP dehydrogenase activity
NWF24_21600	COG0617	tRNA 3'-terminal CCA addition
NWF24_21600	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
NWF24_21610	COG0789	Transcriptional regulator
NWF24_21620	COG1028	Short-chain dehydrogenase reductase Sdr
NWF24_21625	COG2201	protein-glutamate methylesterase activity
NWF24_21635	COG1028	Short-chain dehydrogenase reductase Sdr
NWF24_21640	COG0318	PFAM AMP-dependent synthetase and ligase
NWF24_21645	COG2918	glutathione biosynthetic process
NWF24_21655	COG0400	carboxylic ester hydrolase activity
NWF24_21660	COG3181	Tripartite tricarboxylate transporter family receptor
NWF24_21670	COG0523	cobalamin synthesis protein
NWF24_21680	COG1028	Short-chain dehydrogenase reductase Sdr
NWF24_21735	COG2354	Protein conserved in bacteria
NWF24_21755	COG4628	conserved protein (DUF2132)
NWF24_21770	COG0564	pseudouridine synthase activity
NWF24_21775	COG0589	response to stress
NWF24_21790	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
NWF24_21800	COG1252	NADH dehydrogenase
NWF24_21815	COG1525	nuclease
NWF24_21825	COG0318	PFAM AMP-dependent synthetase and ligase
NWF24_21830	COG1764	response to oxidative stress
NWF24_21850	COG1028	Short-chain dehydrogenase reductase Sdr
NWF24_21860	COG2271	Major facilitator Superfamily
NWF24_21875	COG0765	amino acid transport
NWF24_21880	COG0765	amino acid transport
NWF24_21895	COG0583	DNA-binding transcription factor activity
NWF24_21915	COG0584	glycerophosphoryl diester phosphodiesterase
NWF24_21935	COG2132	Multicopper oxidase
NWF24_21960	COG3191	aminopeptidase activity
NWF24_21975	COG0789	Transcriptional regulator
NWF24_21980	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NWF24_21985	COG0488	(ABC) transporter
NWF24_21990	COG0513	Belongs to the DEAD box helicase family
NWF24_22005	COG3842	ATPase activity
NWF24_22015	COG1175	transmembrane transport
NWF24_22025	COG2186	Transcriptional regulator
NWF24_22030	COG0129	dihydroxy-acid dehydratase activity
NWF24_22040	COG0800	Aldolase
NWF24_22045	COG0235	Class ii aldolase
NWF24_22055	COG1028	Short-chain dehydrogenase reductase Sdr
NWF24_22085	COG1840	ABC-type Fe3 transport system, periplasmic component
NWF24_22095	COG3842	ATPase activity
NWF24_22105	COG0346	lactoylglutathione lyase activity
NWF24_22120	COG0800	Aldolase
NWF24_22150	COG0259	pyridoxamine-phosphate oxidase activity
NWF24_22165	COG0679	Auxin Efflux Carrier
NWF24_22190	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NWF24_22195	COG1309	transcriptional regulator
NWF24_22200	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
NWF24_22205	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NWF24_22225	COG2169	Transcriptional regulator
NWF24_22235	COG0697	spore germination
NWF24_22245	COG0318	PFAM AMP-dependent synthetase and ligase
NWF24_22250	COG3268	Saccharopine dehydrogenase
NWF24_22270	COG0277	FAD linked oxidase domain protein
NWF24_22285	COG0625	glutathione transferase activity
NWF24_22290	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NWF24_22310	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NWF24_22395	COG1301	dicarboxylic acid transport
NWF24_22405	COG1301	dicarboxylic acid transport
NWF24_22450	COG0674	pyruvate-flavodoxin oxidoreductase activity
NWF24_22450	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
NWF24_22460	COG0583	DNA-binding transcription factor activity
NWF24_22470	COG2271	Major facilitator Superfamily
NWF24_22480	COG1012	belongs to the aldehyde dehydrogenase family
NWF24_22490	COG0583	DNA-binding transcription factor activity
NWF24_22495	COG0436	Aminotransferase
NWF24_22505	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
NWF24_22530	COG0179	Fumarylacetoacetate (FAA) hydrolase
NWF24_22535	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NWF24_22555	COG1012	belongs to the aldehyde dehydrogenase family
NWF24_22575	COG0708	Exodeoxyribonuclease III
NWF24_22585	COG3621	Patatin-like phospholipase
NWF24_22595	COG3852	Histidine kinase
NWF24_22605	COG0174	glutamine synthetase
NWF24_22610	COG1058	Belongs to the CinA family
NWF24_22610	COG1546	Belongs to the CinA family
NWF24_22635	COG1187	pseudouridine synthase activity
NWF24_22645	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
NWF24_22645	COG4797	methyltransferase
NWF24_22670	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
NWF24_22690	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
NWF24_22695	COG0077	Prephenate dehydratase
NWF24_22695	COG1605	Chorismate mutase
NWF24_22700	COG0287	Prephenate dehydrogenase
NWF24_22705	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
NWF24_22725	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
NWF24_22750	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NWF24_22755	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
NWF24_22755	COG2111	Na H antiporter
NWF24_22760	COG1006	Multisubunit Na H antiporter MnhC subunit
NWF24_22765	COG0651	ATP synthesis coupled electron transport
NWF24_22775	COG2212	antiporter activity
NWF24_22780	COG1320	monovalent cation:proton antiporter activity
NWF24_22785	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
NWF24_22785	COG3608	succinylglutamate desuccinylase aspartoacylase
NWF24_22855	COG4177	L-phenylalanine transmembrane transporter activity
NWF24_22860	COG0559	Belongs to the binding-protein-dependent transport system permease family
NWF24_22870	COG2188	Transcriptional regulator
NWF24_22885	COG0477	Major facilitator Superfamily
NWF24_22890	COG1262	PFAM Formylglycine-generating sulfatase enzyme
NWF24_22910	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
NWF24_22915	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NWF24_22920	COG0142	geranyltranstransferase activity
NWF24_22925	COG1722	exodeoxyribonuclease VII activity
NWF24_22965	COG3064	Membrane
NWF24_22975	COG2271	Major facilitator Superfamily
NWF24_22980	COG0583	DNA-binding transcription factor activity
NWF24_23025	COG0747	negative chemotaxis
NWF24_23030	COG0601	transmembrane transport
NWF24_23035	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NWF24_23040	COG0444	Belongs to the ABC transporter superfamily
NWF24_23045	COG4608	Belongs to the ABC transporter superfamily
NWF24_23050	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
NWF24_23065	COG0412	Dienelactone hydrolase
NWF24_23090	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NWF24_23100	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NWF24_23125	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
NWF24_23135	COG0210	DNA helicase
NWF24_23140	COG0516	GMP reductase activity
NWF24_23155	COG0300	oxidoreductase activity
NWF24_23175	COG4221	oxidoreductase activity
NWF24_23225	COG1028	Short-chain dehydrogenase reductase Sdr
NWF24_23230	COG1028	Short-chain dehydrogenase reductase Sdr
NWF24_23270	COG0683	leucine binding
NWF24_23285	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
NWF24_23310	COG4638	Rieske (2fe-2S)
NWF24_23335	COG0604	alcohol dehydrogenase
NWF24_23335	COG1028	Short-chain dehydrogenase reductase Sdr
NWF24_23335	COG3321	synthase
NWF24_23340	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NWF24_23355	COG0513	Belongs to the DEAD box helicase family
NWF24_23360	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
NWF24_23370	COG2154	pterin-4-alpha-carbinolamine dehydratase
NWF24_23375	COG1162	GTPase activity
NWF24_23385	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NWF24_23390	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
NWF24_23400	COG0335	large ribosomal subunit rRNA binding
NWF24_23405	COG0336	Belongs to the RNA methyltransferase TrmD family
NWF24_23410	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NWF24_23415	COG0228	four-way junction DNA binding
NWF24_23430	COG0306	phosphate transporter
NWF24_23435	COG1392	Phosphate transport regulator
NWF24_23450	COG0617	tRNA 3'-terminal CCA addition
NWF24_23455	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NWF24_23460	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
NWF24_23475	COG4977	sequence-specific DNA binding
NWF24_23480	COG4977	sequence-specific DNA binding
NWF24_23480	COG1917	Cupin 2, conserved barrel domain protein
NWF24_23490	COG4941	Belongs to the sigma-70 factor family
NWF24_23495	COG3795	YCII-related domain
NWF24_23500	COG3795	YCII-related domain
NWF24_23515	COG0728	peptidoglycan biosynthetic process
NWF24_23520	COG0268	Binds directly to 16S ribosomal RNA
NWF24_23530	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
NWF24_23535	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NWF24_23545	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
NWF24_23560	COG3483	tryptophan 2,3-dioxygenase activity
NWF24_23575	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NWF24_23585	COG1918	ferrous iron import across plasma membrane
NWF24_23585	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
NWF24_23610	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
NWF24_23625	COG1960	acyl-CoA dehydrogenase activity
NWF24_23675	COG4106	trans-aconitate 2-methyltransferase activity
NWF24_23680	COG0039	L-malate dehydrogenase activity
NWF24_23685	COG2188	Transcriptional regulator
NWF24_23700	COG1053	succinate dehydrogenase
NWF24_23705	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
NWF24_23710	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
NWF24_23715	COG0372	Belongs to the citrate synthase family
NWF24_23730	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NWF24_23735	COG0066	3-isopropylmalate dehydratase activity
NWF24_23740	COG0473	3-isopropylmalate dehydrogenase activity
NWF24_23745	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NWF24_23755	COG0101	tRNA pseudouridine synthase activity
NWF24_23760	COG0135	phosphoribosylanthranilate isomerase activity
NWF24_23765	COG0133	tryptophan synthase activity
NWF24_23770	COG0159	tryptophan synthase activity
NWF24_23775	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
NWF24_23780	COG0762	integral membrane protein
NWF24_23790	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
NWF24_23795	COG0443	Heat shock 70 kDa protein
NWF24_23800	COG1451	nucleotide metabolic process
NWF24_23815	COG1472	Belongs to the glycosyl hydrolase 3 family
NWF24_23820	COG0736	holo-[acyl-carrier-protein] synthase activity
NWF24_23825	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
NWF24_23830	COG1381	Involved in DNA repair and RecF pathway recombination
NWF24_23835	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NWF24_23840	COG0571	ribonuclease III activity
NWF24_23850	COG0681	Belongs to the peptidase S26 family
NWF24_23855	COG0481	GTPase activity
NWF24_23860	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NWF24_23885	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
NWF24_23890	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NWF24_23895	COG1028	Short-chain dehydrogenase reductase Sdr
NWF24_23900	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
NWF24_23905	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NWF24_23910	COG0416	fatty acid biosynthetic process
NWF24_23915	COG0333	Belongs to the bacterial ribosomal protein bL32 family
NWF24_23920	COG1399	metal-binding, possibly nucleic acid-binding protein
NWF24_23925	COG0424	maF-like protein
NWF24_23930	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NWF24_23935	COG2223	nitrite transmembrane transporter activity
NWF24_23940	COG0616	signal peptide processing
NWF24_23940	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
NWF24_23960	COG1530	ribonuclease E activity
NWF24_23965	COG0583	DNA-binding transcription factor activity
NWF24_23990	COG0181	hydroxymethylbilane synthase activity
NWF24_23995	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
NWF24_24005	COG3459	Glycosyltransferase 36 associated
NWF24_24020	COG0583	DNA-binding transcription factor activity
NWF24_24055	COG3275	phosphorelay sensor kinase activity
NWF24_24060	COG0165	Argininosuccinate lyase
NWF24_24145	COG0583	DNA-binding transcription factor activity
NWF24_24155	COG3842	ATPase activity
NWF24_24160	COG1176	ABC-type spermidine putrescine transport system, permease component I
NWF24_24165	COG1177	transmembrane transport
NWF24_24185	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NWF24_24190	COG0251	oxidation-reduction process
NWF24_24225	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
NWF24_24230	COG0410	ABC transporter
NWF24_24265	COG1280	lysine exporter protein (LysE YggA)
NWF24_24280	COG2186	Transcriptional regulator
NWF24_24285	COG2807	transmembrane transport
NWF24_24330	COG2267	carboxylic ester hydrolase activity
NWF24_24355	COG4221	oxidoreductase activity
NWF24_24360	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
NWF24_24365	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
NWF24_24365	COG1116	anion transmembrane transporter activity
NWF24_24370	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NWF24_24375	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
NWF24_24400	COG1620	l-lactate permease
NWF24_24405	COG0583	DNA-binding transcription factor activity
NWF24_24415	COG0477	Major facilitator Superfamily
NWF24_24430	COG1028	Short-chain dehydrogenase reductase Sdr
NWF24_24435	COG4948	Mandelate Racemase Muconate Lactonizing
NWF24_24445	COG1172	Belongs to the binding-protein-dependent transport system permease family
NWF24_24455	COG3618	amidohydrolase
NWF24_24460	COG1414	Transcriptional regulator
NWF24_24465	COG0789	Transcriptional regulator
NWF24_24490	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
NWF24_24495	COG0583	DNA-binding transcription factor activity
NWF24_24500	COG3181	Tripartite tricarboxylate transporter family receptor
NWF24_24520	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
NWF24_24525	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NWF24_24545	COG0318	PFAM AMP-dependent synthetase and ligase
NWF24_24555	COG1960	acyl-CoA dehydrogenase activity
NWF24_24565	COG1960	acyl-CoA dehydrogenase activity
NWF24_24580	COG1028	Short-chain dehydrogenase reductase Sdr
NWF24_24585	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
NWF24_24585	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
NWF24_24600	COG3022	response to hydroperoxide
NWF24_24605	COG0525	valine-tRNA ligase activity
NWF24_24615	COG0425	Belongs to the sulfur carrier protein TusA family
NWF24_24620	COG2816	NAD+ diphosphatase activity
NWF24_24635	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NWF24_24665	COG0559	Belongs to the binding-protein-dependent transport system permease family
NWF24_24670	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
NWF24_24675	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
NWF24_24680	COG1674	ftsk spoiiie
NWF24_24690	COG0492	ferredoxin-NADP+ reductase activity
NWF24_24695	COG0227	Belongs to the bacterial ribosomal protein bL28 family
NWF24_24700	COG0267	Belongs to the bacterial ribosomal protein bL33 family
NWF24_24710	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NWF24_24710	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NWF24_24730	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NWF24_24735	COG1960	acyl-CoA dehydrogenase activity
NWF24_24760	COG0196	riboflavin kinase activity
NWF24_24770	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NWF24_24775	COG1609	Transcriptional regulator
NWF24_24800	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
NWF24_24805	COG1283	sodium-dependent phosphate transmembrane transporter activity
NWF24_24830	COG1028	Short-chain dehydrogenase reductase Sdr
NWF24_24845	COG3181	Tripartite tricarboxylate transporter family receptor
NWF24_24850	COG0583	DNA-binding transcription factor activity
NWF24_24865	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
NWF24_24870	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
NWF24_24885	COG0084	hydrolase, TatD family'
NWF24_24890	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NWF24_24895	COG0714	Associated with various cellular activities
NWF24_24905	COG2304	oxidoreductase activity
NWF24_24910	COG1309	transcriptional regulator
NWF24_24920	COG1024	Enoyl-CoA hydratase
NWF24_24925	COG2050	protein possibly involved in aromatic compounds catabolism
NWF24_24935	COG3396	Phenylacetate-CoA oxygenase
NWF24_24940	COG3460	Phenylacetate-CoA oxygenase
NWF24_24945	COG3396	Phenylacetate-CoA oxygenase
NWF24_24950	COG2151	metal-sulfur cluster biosynthetic enzyme
NWF24_24955	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NWF24_24980	COG1012	belongs to the aldehyde dehydrogenase family
NWF24_24980	COG2030	dehydratase
NWF24_24985	COG1028	Short-chain dehydrogenase reductase Sdr
NWF24_25000	COG0671	phosphoesterase, PA-phosphatase related
NWF24_25005	COG0463	Glycosyl transferase, family 2
NWF24_25010	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NWF24_25025	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NWF24_25030	COG0384	phenazine biosynthesis protein PhzF
NWF24_25040	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NWF24_25045	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NWF24_25050	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
NWF24_25110	COG0583	DNA-binding transcription factor activity
NWF24_25135	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
NWF24_25165	COG0601	transmembrane transport
NWF24_25180	COG0251	oxidation-reduction process
NWF24_25185	COG0740	serine-type endopeptidase activity
NWF24_25190	COG1595	DNA-templated transcription, initiation
NWF24_25200	COG1136	(ABC) transporter
NWF24_25205	COG4591	ABC-type transport system involved in lipoprotein release permease component
NWF24_25225	COG3831	ATPase activity
NWF24_25235	COG0714	Associated with various cellular activities
NWF24_25240	COG2425	protein containing a von Willebrand factor type A (vWA) domain
NWF24_25245	COG3552	Protein containing von Willebrand factor type A (VWA) domain
NWF24_25250	COG4715	Zinc finger, swim domain protein
NWF24_25260	COG2969	positive regulation of protein catabolic process
NWF24_25265	COG0625	glutathione transferase activity
NWF24_25270	COG2857	Cytochrome c1
NWF24_25275	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
NWF24_25280	COG0723	plastoquinol--plastocyanin reductase activity
NWF24_25295	COG1970	mechanosensitive ion channel activity
NWF24_25300	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
NWF24_25305	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NWF24_25320	COG0805	protein transport
NWF24_25325	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NWF24_25330	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NWF24_25335	COG0537	adenosine 5'-monophosphoramidase activity
NWF24_25345	COG0140	phosphoribosyl-ATP diphosphatase activity
NWF24_25350	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
NWF24_25355	COG0107	imidazoleglycerol-phosphate synthase activity
NWF24_25365	COG1301	dicarboxylic acid transport
NWF24_25370	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NWF24_25380	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
NWF24_25390	COG0131	Imidazoleglycerol-phosphate dehydratase
NWF24_25395	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NWF24_25420	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
NWF24_25425	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NWF24_25430	COG5007	Belongs to the BolA IbaG family
NWF24_25435	COG0842	Transport permease protein
NWF24_25440	COG1131	(ABC) transporter
NWF24_25455	COG2853	Lipoprotein
NWF24_25460	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
NWF24_25465	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
NWF24_25470	COG1127	ABC transporter
NWF24_25480	COG0067	glutamate synthase
NWF24_25480	COG0069	glutamate synthase activity
NWF24_25480	COG0070	glutamate synthase
NWF24_25505	COG0232	Belongs to the dGTPase family. Type 2 subfamily
NWF24_25510	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
NWF24_25515	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
NWF24_25550	COG1965	Belongs to the frataxin family
NWF24_25560	COG0019	diaminopimelate decarboxylase activity
NWF24_25565	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
NWF24_25570	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
NWF24_25575	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
NWF24_25580	COG1333	cytochrome c biogenesis protein
NWF24_25590	COG0218	Necessary for normal cell division and for the maintenance of normal septation
NWF24_25600	COG1560	Kdo2-lipid A biosynthetic process
NWF24_25610	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NWF24_25615	COG4772	TonB-dependent receptor
NWF24_25630	COG4774	siderophore transport
NWF24_25635	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NWF24_25670	COG0765	amino acid transport
NWF24_25675	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NWF24_25685	COG4670	ketone body catabolic process
NWF24_25690	COG1960	acyl-CoA dehydrogenase activity
NWF24_25700	COG1609	Transcriptional regulator
NWF24_25710	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NWF24_25715	COG1126	abc transporter atp-binding protein
NWF24_25725	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
NWF24_25735	COG1609	Transcriptional regulator
NWF24_25740	COG3485	protocatechuate 3,4-dioxygenase
NWF24_25750	COG3246	L-lysine catabolic process to acetate
NWF24_25820	COG2205	protein histidine kinase activity
NWF24_25835	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NWF24_25840	COG0459	protein refolding
NWF24_25845	COG1070	Carbohydrate kinase
NWF24_25850	COG2207	Transcriptional regulator
NWF24_25850	COG4753	response regulator
NWF24_25860	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
NWF24_25870	COG0246	Mannitol dehydrogenase
NWF24_25875	COG3842	ATPase activity
NWF24_25880	COG0395	ABC-type sugar transport system, permease component
NWF24_25885	COG1175	transmembrane transport
NWF24_25915	COG0166	Belongs to the GPI family
NWF24_25920	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
NWF24_25935	COG3842	ATPase activity
NWF24_25945	COG1840	ABC-type Fe3 transport system, periplasmic component
NWF24_25950	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NWF24_25955	COG3384	dioxygenase
NWF24_25970	COG4608	Belongs to the ABC transporter superfamily
NWF24_25975	COG0444	Belongs to the ABC transporter superfamily
NWF24_25980	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NWF24_25990	COG1473	amidohydrolase
NWF24_26005	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
NWF24_26010	COG1765	OsmC-like protein
NWF24_26025	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NWF24_26050	COG4795	General secretion pathway protein
NWF24_26130	COG2233	PERMEase
NWF24_26140	COG0753	catalase activity
NWF24_26150	COG2863	cytochrome
NWF24_26160	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NWF24_26165	COG2271	Major facilitator Superfamily
NWF24_26170	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NWF24_26185	COG3842	ATPase activity
NWF24_26190	COG1840	ABC-type Fe3 transport system, periplasmic component
NWF24_26200	COG4178	(ABC) transporter
NWF24_26205	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
NWF24_26215	COG1785	Belongs to the alkaline phosphatase family
NWF24_26235	COG1132	(ABC) transporter
NWF24_26240	COG0189	ligase activity
NWF24_26240	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NWF24_26245	COG0189	ligase activity
NWF24_26245	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NWF24_26275	COG1172	Belongs to the binding-protein-dependent transport system permease family
NWF24_26280	COG1172	Belongs to the binding-protein-dependent transport system permease family
NWF24_26285	COG1129	ABC transporter
NWF24_26290	COG4214	carbohydrate transport
NWF24_26300	COG4213	ABC transporter substrate-binding protein
NWF24_26305	COG1879	ABC-type sugar transport system periplasmic component
NWF24_26310	COG1012	belongs to the aldehyde dehydrogenase family
NWF24_26320	COG1028	Short-chain dehydrogenase reductase Sdr
NWF24_26325	COG3386	PFAM SMP-30 Gluconolaconase
NWF24_26355	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
NWF24_26360	COG2885	chlorophyll binding
NWF24_26365	COG0583	DNA-binding transcription factor activity
NWF24_26370	COG0697	spore germination
NWF24_26375	COG1902	pentaerythritol trinitrate reductase activity
NWF24_26380	COG0583	DNA-binding transcription factor activity
NWF24_26400	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
NWF24_26425	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
NWF24_26425	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
NWF24_26425	COG0506	proline dehydrogenase activity
NWF24_26440	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
NWF24_26490	COG0656	L-ascorbic acid biosynthetic process
NWF24_26515	COG2814	Major facilitator Superfamily
NWF24_26560	COG1522	sequence-specific DNA binding
NWF24_26565	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NWF24_26575	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NWF24_26590	COG0583	DNA-binding transcription factor activity
NWF24_26595	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NWF24_26605	COG1285	pathogenesis
NWF24_26610	COG0625	glutathione transferase activity
NWF24_26620	COG0617	tRNA 3'-terminal CCA addition
NWF24_26635	COG3387	PFAM Glycoside hydrolase 15-related
NWF24_26640	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
NWF24_26650	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NWF24_26685	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NWF24_26690	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
NWF24_26700	COG2175	clavaminate synthase activity
NWF24_26710	COG1028	Short-chain dehydrogenase reductase Sdr
NWF24_26720	COG2814	Major facilitator Superfamily
NWF24_26725	COG0583	DNA-binding transcription factor activity
NWF24_26730	COG0037	tRNA processing
NWF24_26750	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NWF24_26755	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NWF24_26765	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NWF24_26770	COG2205	protein histidine kinase activity
NWF24_26780	COG2204	response regulator
NWF24_26805	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NWF24_26810	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
NWF24_26840	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NWF24_26850	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NWF24_26860	COG2264	protein methyltransferase activity
NWF24_26865	COG0439	Biotin carboxylase
NWF24_26870	COG0511	ligase activity, forming carbon-carbon bonds
NWF24_26875	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NWF24_26885	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
NWF24_26895	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
NWF24_26905	COG0312	modulator of DNA gyrase
NWF24_26910	COG0772	Belongs to the SEDS family
NWF24_26925	COG2197	response regulator
NWF24_26930	COG3150	esterase
NWF24_26945	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NWF24_26965	COG0575	Belongs to the CDS family
NWF24_26975	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
NWF24_26980	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NWF24_26985	COG0583	DNA-binding transcription factor activity
NWF24_27000	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
NWF24_27015	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
NWF24_27020	COG1181	Belongs to the D-alanine--D-alanine ligase family
NWF24_27025	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
NWF24_27030	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NWF24_27035	COG0772	Belongs to the SEDS family
NWF24_27040	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NWF24_27045	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NWF24_27050	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
NWF24_27055	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NWF24_27070	COG0275	rRNA processing
NWF24_27075	COG2001	Belongs to the MraZ family
NWF24_27080	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
NWF24_27085	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
NWF24_27105	COG0523	cobalamin synthesis protein
NWF24_27110	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
NWF24_27115	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
NWF24_27130	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
NWF24_27150	COG0402	S-adenosylhomocysteine deaminase activity
NWF24_27160	COG1335	isochorismatase
NWF24_27165	COG0583	DNA-binding transcription factor activity
NWF24_27195	COG1595	DNA-templated transcription, initiation
NWF24_27235	COG0583	DNA-binding transcription factor activity
NWF24_27245	COG2207	Transcriptional regulator
NWF24_27245	COG0662	Cupin 2, conserved barrel domain protein
NWF24_27270	COG2814	Major facilitator Superfamily
NWF24_27275	COG0656	L-ascorbic acid biosynthetic process
NWF24_27300	COG0590	tRNA wobble adenosine to inosine editing
NWF24_27305	COG2807	transmembrane transport
NWF24_27315	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NWF24_27345	COG1187	pseudouridine synthase activity
NWF24_27365	COG1566	PFAM secretion protein HlyD family protein
NWF24_27380	COG1846	Transcriptional regulator
NWF24_27395	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
NWF24_27405	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NWF24_27415	COG0501	Belongs to the peptidase M48B family
NWF24_27430	COG0418	dihydroorotase activity
NWF24_27455	COG0601	transmembrane transport
NWF24_27460	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NWF24_27465	COG4608	Belongs to the ABC transporter superfamily
NWF24_27470	COG0444	Belongs to the ABC transporter superfamily
NWF24_27475	COG0154	amidase activity
NWF24_27500	COG0583	DNA-binding transcription factor activity
NWF24_27505	COG1250	3-hydroxyacyl-CoA dehydrogenase
NWF24_27505	COG1024	Enoyl-CoA hydratase
NWF24_27510	COG0183	Belongs to the thiolase family
NWF24_27515	COG1960	acyl-CoA dehydrogenase activity
NWF24_27520	COG1960	acyl-CoA dehydrogenase activity
NWF24_27530	COG1804	L-carnitine dehydratase bile acid-inducible protein F
NWF24_27540	COG0318	PFAM AMP-dependent synthetase and ligase
NWF24_27575	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
NWF24_27580	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
NWF24_27580	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
NWF24_27585	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
NWF24_27605	COG2226	methyltransferase
NWF24_27610	COG1126	abc transporter atp-binding protein
NWF24_27615	COG0765	amino acid transport
NWF24_27620	COG0765	amino acid transport
NWF24_27625	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NWF24_27630	COG1027	Aspartate ammonia-lyase
NWF24_27635	COG0583	DNA-binding transcription factor activity
NWF24_27640	COG0154	amidase activity
NWF24_27645	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NWF24_27650	COG5265	(ABC) transporter
NWF24_27660	COG0683	leucine binding
NWF24_27665	COG1024	Enoyl-CoA hydratase
NWF24_27690	COG0183	Belongs to the thiolase family
NWF24_27695	COG1250	3-hydroxyacyl-CoA dehydrogenase
NWF24_27695	COG1024	Enoyl-CoA hydratase
NWF24_27705	COG1960	acyl-CoA dehydrogenase activity
NWF24_27715	COG4221	oxidoreductase activity
NWF24_27730	COG0179	Fumarylacetoacetate (FAA) hydrolase
NWF24_27735	COG1028	Short-chain dehydrogenase reductase Sdr
NWF24_27740	COG1028	Short-chain dehydrogenase reductase Sdr
NWF24_27745	COG2186	Transcriptional regulator
NWF24_27750	COG2721	sulfolactate sulfo-lyase activity
NWF24_27755	COG3386	PFAM SMP-30 Gluconolaconase
NWF24_27760	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
NWF24_27770	COG1309	transcriptional regulator
NWF24_27775	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
NWF24_27790	COG1215	transferase activity, transferring glycosyl groups
NWF24_27795	COG0438	transferase activity, transferring glycosyl groups
NWF24_27795	COG1216	Glycosyl transferase, family 2
NWF24_27800	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
NWF24_27800	COG0662	Cupin 2, conserved barrel domain protein
NWF24_27830	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
NWF24_27850	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NWF24_27865	COG0277	FAD linked oxidase domain protein
NWF24_27870	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
NWF24_27870	COG0546	phosphoglycolate phosphatase activity
NWF24_27910	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
NWF24_27915	COG1215	transferase activity, transferring glycosyl groups
NWF24_27935	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NWF24_27950	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NWF24_27960	COG0697	spore germination
NWF24_27965	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NWF24_27975	COG0384	phenazine biosynthesis protein PhzF
NWF24_27980	COG0625	glutathione transferase activity
NWF24_27985	COG0384	phenazine biosynthesis protein PhzF
NWF24_28000	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NWF24_28005	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NWF24_28010	COG1529	Aldehyde oxidase and xanthine dehydrogenase
NWF24_28015	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
NWF24_28020	COG2080	2 iron, 2 sulfur cluster binding
NWF24_28030	COG0642	Histidine kinase
NWF24_28035	COG0745	RESPONSE REGULATOR receiver
NWF24_28050	COG0726	polysaccharide deacetylase
NWF24_28050	COG1649	PFAM Uncharacterised BCR, COG1649
NWF24_28055	COG1215	transferase activity, transferring glycosyl groups
NWF24_28065	COG1028	Short-chain dehydrogenase reductase Sdr
NWF24_28070	COG0583	DNA-binding transcription factor activity
NWF24_28080	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NWF24_28100	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NWF24_28120	COG4977	sequence-specific DNA binding
NWF24_28120	COG1917	Cupin 2, conserved barrel domain protein
NWF24_28135	COG1129	ABC transporter
NWF24_28185	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
NWF24_28190	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NWF24_28205	COG0679	Auxin Efflux Carrier
NWF24_28210	COG0210	DNA helicase
NWF24_28225	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
NWF24_28240	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NWF24_28245	COG2274	protein secretion by the type I secretion system
NWF24_28255	COG0644	oxidoreductase
NWF24_28270	COG5002	protein histidine kinase activity
NWF24_28270	COG0784	Response regulator, receiver
NWF24_28270	COG2198	Histidine kinase
NWF24_28275	COG0745	RESPONSE REGULATOR receiver
NWF24_28290	COG1301	dicarboxylic acid transport
NWF24_28295	COG0477	Major facilitator Superfamily
NWF24_28305	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
NWF24_28310	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
NWF24_28315	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
NWF24_28320	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
NWF24_28325	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
NWF24_28355	COG2204	response regulator
NWF24_28360	COG5000	phosphorelay sensor kinase activity
NWF24_28380	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NWF24_28385	COG0085	RNA polymerase activity
NWF24_28390	COG0222	ribosome binding
NWF24_28395	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NWF24_28400	COG0081	regulation of translation
NWF24_28405	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NWF24_28445	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NWF24_28450	COG0134	indole-3-glycerol-phosphate synthase activity
NWF24_28455	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NWF24_28460	COG1280	lysine exporter protein (LysE YggA)
NWF24_28490	COG0546	phosphoglycolate phosphatase activity
NWF24_28500	COG4221	oxidoreductase activity
NWF24_28515	COG0583	DNA-binding transcription factor activity
NWF24_28560	COG0583	DNA-binding transcription factor activity
NWF24_28570	COG1414	Transcriptional regulator
NWF24_28580	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
NWF24_28585	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NWF24_28590	COG3181	Tripartite tricarboxylate transporter family receptor
NWF24_28605	COG3386	PFAM SMP-30 Gluconolaconase
NWF24_28610	COG1959	2 iron, 2 sulfur cluster binding
NWF24_28625	COG1595	DNA-templated transcription, initiation
NWF24_28635	COG4774	siderophore transport
NWF24_28640	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NWF24_28665	COG2144	transferase activity, transferring acyl groups
NWF24_28675	COG2072	flavoprotein involved in K transport
NWF24_28850	COG0515	serine threonine protein kinase
NWF24_28875	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
NWF24_28880	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
NWF24_28895	COG4251	negative regulation of phosphorylation
NWF24_28900	COG4977	sequence-specific DNA binding
NWF24_28905	COG1335	isochorismatase
NWF24_28915	COG2831	hemolysin activation secretion protein
NWF24_28980	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
NWF24_28990	COG2967	ApaG domain
NWF24_29005	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
NWF24_29045	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
NWF24_29080	COG0653	protein targeting
NWF24_29085	COG0069	glutamate synthase activity
NWF24_29115	COG3038	cytochrome b561
NWF24_29135	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NWF24_29140	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
NWF24_29145	COG1137	ATPase activity
NWF24_29150	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
NWF24_29165	COG0018	arginyl-trna synthetase
NWF24_29195	COG1804	L-carnitine dehydratase bile acid-inducible protein F
NWF24_29200	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NWF24_29205	COG1414	Transcriptional regulator
NWF24_29210	COG3181	Tripartite tricarboxylate transporter family receptor
NWF24_29215	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NWF24_29220	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
NWF24_29245	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
NWF24_29250	COG0583	DNA-binding transcription factor activity
NWF24_29260	COG1024	Enoyl-CoA hydratase
NWF24_29265	COG0205	6-phosphofructokinase activity
NWF24_29280	COG2814	Major facilitator Superfamily
NWF24_29290	COG0121	glutamine amidotransferase
NWF24_29300	COG0189	ligase activity
NWF24_29320	COG3158	transport of potassium into the cell
NWF24_29330	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NWF24_29345	COG0495	leucyl-tRNA aminoacylation
NWF24_29370	COG2072	flavoprotein involved in K transport
NWF24_29375	COG0366	Alpha amylase catalytic
NWF24_29380	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
NWF24_29390	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
NWF24_29395	COG0297	glycogen (starch) synthase activity
NWF24_29400	COG0058	SHG alpha-glucan phosphorylase activity
NWF24_29415	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
NWF24_29420	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NWF24_29425	COG0735	belongs to the Fur family
NWF24_29430	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
NWF24_29440	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NWF24_29450	COG0598	Magnesium transport protein CorA
NWF24_29465	COG0747	negative chemotaxis
NWF24_29470	COG4608	Belongs to the ABC transporter superfamily
NWF24_29475	COG0444	Belongs to the ABC transporter superfamily
NWF24_29480	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NWF24_29485	COG0601	transmembrane transport
NWF24_29490	COG0318	PFAM AMP-dependent synthetase and ligase
NWF24_29510	COG0745	RESPONSE REGULATOR receiver
NWF24_29525	COG0482	sulfurtransferase activity
NWF24_29530	COG0318	PFAM AMP-dependent synthetase and ligase
NWF24_29535	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NWF24_29575	COG1268	BioY protein
NWF24_29585	COG1122	ATPase activity
NWF24_29590	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
NWF24_29600	COG0217	transcriptional regulatory protein
NWF24_29635	COG1522	sequence-specific DNA binding
NWF24_29640	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
NWF24_29645	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
NWF24_29655	COG1012	belongs to the aldehyde dehydrogenase family
NWF24_29665	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NWF24_29670	COG4166	transmembrane transport
NWF24_29680	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NWF24_29690	COG0473	3-isopropylmalate dehydrogenase activity
NWF24_29695	COG1012	belongs to the aldehyde dehydrogenase family
NWF24_29720	COG0765	amino acid transport
NWF24_29725	COG1126	abc transporter atp-binding protein
NWF24_29730	COG1522	sequence-specific DNA binding
NWF24_29740	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NWF24_29745	COG0028	Belongs to the TPP enzyme family
NWF24_29750	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NWF24_29760	COG1953	Uracil, thiamine, allantoin
NWF24_29765	COG2188	Transcriptional regulator
NWF24_29770	COG0629	single-stranded DNA binding
NWF24_29785	COG2188	Transcriptional regulator
NWF24_29790	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
NWF24_29795	COG1070	Carbohydrate kinase
NWF24_29805	COG1129	ABC transporter
NWF24_29810	COG1172	Belongs to the binding-protein-dependent transport system permease family
NWF24_29815	COG0667	Aldo Keto reductase
NWF24_29870	COG1028	Short-chain dehydrogenase reductase Sdr
NWF24_29885	COG1946	Acyl-CoA thioesterase
NWF24_29895	COG0445	tRNA wobble uridine modification
NWF24_29900	COG3181	Tripartite tricarboxylate transporter family receptor
NWF24_29910	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NWF24_29925	COG0583	DNA-binding transcription factor activity
NWF24_29965	COG1404	Belongs to the peptidase S8 family
NWF24_29970	COG1804	L-carnitine dehydratase bile acid-inducible protein F
NWF24_29975	COG4977	sequence-specific DNA binding
NWF24_29980	COG1879	ABC-type sugar transport system periplasmic component
NWF24_29990	COG1172	Belongs to the binding-protein-dependent transport system permease family
NWF24_29995	COG1063	alcohol dehydrogenase
NWF24_30000	COG1070	Carbohydrate kinase
NWF24_30005	COG1028	Short-chain dehydrogenase reductase Sdr
NWF24_30020	COG0243	molybdopterin cofactor binding
NWF24_30035	COG1473	amidohydrolase
NWF24_30045	COG0584	glycerophosphoryl diester phosphodiesterase
NWF24_30055	COG2733	membrane
NWF24_30070	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
NWF24_30085	COG1960	acyl-CoA dehydrogenase activity
NWF24_30090	COG1960	acyl-CoA dehydrogenase activity
NWF24_30095	COG0330	HflC and HflK could
NWF24_30105	COG0513	Belongs to the DEAD box helicase family
NWF24_30110	COG0023	Translation Initiation Factor
NWF24_30120	COG0724	RNA recognition motif
NWF24_30135	COG0004	ammonium transporteR
NWF24_30145	COG0028	Belongs to the TPP enzyme family
NWF24_30150	COG0436	Aminotransferase
NWF24_30175	COG3842	ATPase activity
NWF24_30180	COG1176	ABC-type spermidine putrescine transport system, permease component I
NWF24_30185	COG1177	transmembrane transport
NWF24_30240	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
NWF24_30245	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NWF24_30265	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
NWF24_30280	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NWF24_30290	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
NWF24_30300	COG0179	Fumarylacetoacetate (FAA) hydrolase
NWF24_30305	COG0768	penicillin binding
NWF24_30315	COG1792	Involved in formation and maintenance of cell shape
NWF24_30320	COG1077	Cell shape determining protein MreB Mrl
NWF24_30325	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NWF24_30330	COG0154	amidase activity
NWF24_30335	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NWF24_30345	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NWF24_30350	COG0708	Exodeoxyribonuclease III
NWF24_30385	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
NWF24_30395	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
NWF24_30400	COG1335	isochorismatase
NWF24_30405	COG0583	DNA-binding transcription factor activity
NWF24_30410	COG0583	DNA-binding transcription factor activity
NWF24_30435	COG3845	ABC transporter
NWF24_30440	COG1335	isochorismatase
NWF24_30445	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NWF24_30450	COG1079	Belongs to the binding-protein-dependent transport system permease family
NWF24_30475	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NWF24_30480	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
NWF24_30490	COG0501	Belongs to the peptidase M48B family
NWF24_30495	COG2223	nitrite transmembrane transporter activity
NWF24_30510	COG0745	RESPONSE REGULATOR receiver
NWF24_30535	COG2974	May be involved in recombination
NWF24_30540	COG1473	amidohydrolase
NWF24_30550	COG0583	DNA-binding transcription factor activity
NWF24_30570	COG1846	Transcriptional regulator
NWF24_30585	COG1012	belongs to the aldehyde dehydrogenase family
NWF24_30610	COG3971	2-oxopent-4-enoate hydratase activity
NWF24_30635	COG0129	dihydroxy-acid dehydratase activity
NWF24_30650	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NWF24_30660	COG1596	polysaccharide export
NWF24_30670	COG0489	protein tyrosine kinase activity
NWF24_30670	COG3206	protein involved in exopolysaccharide biosynthesis
NWF24_30725	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NWF24_30730	COG0477	Major facilitator Superfamily
NWF24_30740	COG0386	Belongs to the glutathione peroxidase family
NWF24_30750	COG0247	lactate metabolic process
NWF24_30755	COG0277	FAD linked oxidase domain protein
NWF24_30760	COG0277	FAD linked oxidase domain protein
NWF24_30765	COG0583	DNA-binding transcription factor activity
NWF24_30775	COG0004	ammonium transporteR
NWF24_30780	COG0347	Belongs to the P(II) protein family
NWF24_31040	COG1529	Aldehyde oxidase and xanthine dehydrogenase
NWF24_31040	COG2010	Cytochrome c
NWF24_31045	COG2080	2 iron, 2 sulfur cluster binding
NWF24_31055	COG1335	isochorismatase
NWF24_31065	COG0411	ABC transporter
NWF24_31105	COG1309	transcriptional regulator
NWF24_31130	COG1410	methionine synthase
NWF24_31130	COG0646	methionine synthase
NWF24_31135	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
NWF24_31140	COG5380	lipid catabolic process
NWF24_31150	COG0583	DNA-binding transcription factor activity
NWF24_31155	COG1309	transcriptional regulator
NWF24_31160	COG2130	NADP-dependent
NWF24_31185	COG0402	S-adenosylhomocysteine deaminase activity
NWF24_31190	COG1228	amidohydrolase
NWF24_31200	COG0765	amino acid transport
NWF24_31205	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NWF24_31220	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
NWF24_31225	COG2986	histidine ammonia-lyase
NWF24_31240	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NWF24_31250	COG0514	ATP-dependent DNA helicase (RecQ)
NWF24_31265	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NWF24_31270	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NWF24_31280	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
NWF24_31355	COG0633	Ferredoxin
NWF24_31360	COG0683	leucine binding
NWF24_31380	COG0410	ABC transporter
NWF24_31390	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NWF24_31395	COG0700	Nucleoside recognition
NWF24_31400	COG2015	COG2015, Alkyl sulfatase and related hydrolases
NWF24_31410	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NWF24_31425	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NWF24_31445	COG0583	DNA-binding transcription factor activity
NWF24_31455	COG2066	Belongs to the glutaminase family
NWF24_31460	COG0702	epimerase
NWF24_31475	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NWF24_31490	COG0583	DNA-binding transcription factor activity
NWF24_31505	COG1573	uracil-dna glycosylase
NWF24_31515	COG0583	DNA-binding transcription factor activity
NWF24_31530	COG1760	l-serine dehydratase
NWF24_31535	COG1473	amidohydrolase
NWF24_31560	COG1764	response to oxidative stress
NWF24_31570	COG1804	L-carnitine dehydratase bile acid-inducible protein F
NWF24_31575	COG1960	acyl-CoA dehydrogenase activity
NWF24_31580	COG0583	DNA-binding transcription factor activity
NWF24_31590	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
NWF24_31600	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NWF24_31620	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NWF24_31625	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NWF24_31630	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
NWF24_31700	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
NWF24_31720	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NWF24_31765	COG3246	L-lysine catabolic process to acetate
NWF24_31775	COG1250	3-hydroxyacyl-CoA dehydrogenase
NWF24_31780	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NWF24_31790	COG0477	Major facilitator Superfamily
NWF24_31815	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NWF24_31840	COG2050	protein possibly involved in aromatic compounds catabolism
NWF24_31845	COG2233	PERMEase
NWF24_31850	COG0850	regulation of cytokinetic process
NWF24_31855	COG2894	cell division
NWF24_31860	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
NWF24_31885	COG0583	DNA-binding transcription factor activity
NWF24_31900	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NWF24_31950	COG2096	Adenosyltransferase
NWF24_31960	COG0277	FAD linked oxidase domain protein
NWF24_31970	COG1475	DNA binding
NWF24_31980	COG1192	Involved in chromosome partitioning
NWF24_31990	COG0357	Ribosomal RNA small subunit methyltransferase G
NWF24_31995	COG0445	tRNA wobble uridine modification
NWF24_32015	COG1024	Enoyl-CoA hydratase
NWF24_32025	COG1902	pentaerythritol trinitrate reductase activity
NWF24_32035	COG0456	acetyltransferase
NWF24_32040	COG0346	lactoylglutathione lyase activity
NWF24_32045	COG0642	Histidine kinase
NWF24_32050	COG0745	RESPONSE REGULATOR receiver
NWF24_32060	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NWF24_32075	COG0456	acetyltransferase
NWF24_32080	COG2217	Heavy metal translocating P-type atpase
NWF24_32085	COG2608	mercury ion transmembrane transporter activity
NWF24_32100	COG0745	RESPONSE REGULATOR receiver
NWF24_32105	COG2205	protein histidine kinase activity
NWF24_32120	COG1472	Belongs to the glycosyl hydrolase 3 family
NWF24_32125	COG4452	Inner membrane protein CreD
NWF24_32145	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NWF24_32175	COG3568	Endonuclease Exonuclease Phosphatase
NWF24_32180	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NWF24_32185	COG0392	lysyltransferase activity
NWF24_32195	COG1408	metallophosphoesterase
NWF24_32220	COG1335	isochorismatase
NWF24_32230	COG3181	Tripartite tricarboxylate transporter family receptor
NWF24_32245	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NWF24_32260	COG0592	DNA-directed DNA polymerase activity
NWF24_32265	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NWF24_32270	COG0230	Belongs to the bacterial ribosomal protein bL34 family
NWF24_32275	COG0594	ribonuclease P activity
NWF24_32280	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
NWF24_32285	COG0706	membrane insertase activity
NWF24_32290	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NWF24_32295	COG2066	Belongs to the glutaminase family
NWF24_32295	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
NWF24_32315	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
NWF24_32325	COG1028	Short-chain dehydrogenase reductase Sdr
NWF24_32330	COG0724	RNA recognition motif
NWF24_32335	COG2119	membrane
NWF24_32340	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NWF24_32345	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NWF24_32345	COG2813	Specifically methylates the guanine in position
NWF24_32350	COG1739	Uncharacterized protein family UPF0029
NWF24_32355	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NWF24_32375	COG2267	carboxylic ester hydrolase activity
NWF24_32380	COG2814	Major facilitator Superfamily
NWF24_32385	COG3831	ATPase activity
NWF24_32400	COG1385	rRNA (uridine-N3-)-methyltransferase activity
NWF24_32410	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
NWF24_32415	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
NWF24_32420	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
NWF24_32440	COG0281	malic enzyme
NWF24_32440	COG0280	phosphate acetyltransferase
NWF24_32460	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
NWF24_32485	COG2373	Large extracellular alpha-helical protein
NWF24_32490	COG4953	penicillin-binding protein 1C
NWF24_32515	COG0667	Aldo Keto reductase
NWF24_32520	COG5002	protein histidine kinase activity
NWF24_32530	COG2197	response regulator
NWF24_32550	COG0006	proline dipeptidase activity
NWF24_32555	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
NWF24_32560	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
NWF24_32565	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
NWF24_32570	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
NWF24_32585	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
NWF24_32590	COG1914	H( )-stimulated, divalent metal cation uptake system
NWF24_32605	COG0583	DNA-binding transcription factor activity
NWF24_32615	COG3181	Tripartite tricarboxylate transporter family receptor
NWF24_32635	COG0583	DNA-binding transcription factor activity
NWF24_32645	COG1126	abc transporter atp-binding protein
NWF24_32665	COG2072	flavoprotein involved in K transport
NWF24_32685	COG0006	proline dipeptidase activity
NWF24_32700	COG1047	Peptidyl-prolyl cis-trans
NWF24_32705	COG0583	DNA-binding transcription factor activity
NWF24_32730	COG0747	negative chemotaxis
NWF24_32740	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NWF24_32745	COG4172	Belongs to the ABC transporter superfamily
NWF24_32750	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
NWF24_32755	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
NWF24_32765	COG1802	Transcriptional regulator
NWF24_32785	COG1473	amidohydrolase
NWF24_32800	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NWF24_32830	COG1802	Transcriptional regulator
NWF24_32840	COG0697	spore germination
NWF24_32855	COG0789	Transcriptional regulator
NWF24_32875	COG0513	Belongs to the DEAD box helicase family
NWF24_32880	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NWF24_32890	COG2814	Major facilitator Superfamily
NWF24_32905	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
NWF24_32915	COG0583	DNA-binding transcription factor activity
NWF24_32920	COG0300	oxidoreductase activity
NWF24_32930	COG3181	Tripartite tricarboxylate transporter family receptor
NWF24_32935	COG0583	DNA-binding transcription factor activity
NWF24_32945	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NWF24_32945	COG0551	DNA topoisomerase type I activity
NWF24_32955	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
NWF24_32955	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
NWF24_32965	COG0642	Histidine kinase
NWF24_32980	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NWF24_32985	COG2137	regulation of response to DNA damage stimulus
NWF24_33005	COG1126	abc transporter atp-binding protein
NWF24_33010	COG0765	amino acid transport
NWF24_33015	COG0765	amino acid transport
NWF24_33020	COG2721	sulfolactate sulfo-lyase activity
NWF24_33030	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
NWF24_33035	COG1028	Short-chain dehydrogenase reductase Sdr
NWF24_33040	COG1414	Transcriptional regulator
NWF24_33045	COG4682	membrane
NWF24_33055	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
NWF24_33060	COG0045	succinate-CoA ligase (ADP-forming) activity
NWF24_33065	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
NWF24_33070	COG0861	Integral membrane protein TerC family
NWF24_33080	COG1716	ATPase activity
NWF24_33090	COG1234	tRNA 3'-trailer cleavage
NWF24_33150	COG0315	cyclic pyranopterin monophosphate synthase activity
NWF24_33155	COG4783	chaperone-mediated protein folding
NWF24_33160	COG1950	PFAM Membrane protein of
NWF24_33170	COG0861	Integral membrane protein TerC family
NWF24_33195	COG0625	glutathione transferase activity
NWF24_33200	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
NWF24_33225	COG1595	DNA-templated transcription, initiation
NWF24_33230	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NWF24_33240	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
NWF24_33260	COG4566	intracellular signal transduction
NWF24_33290	COG1522	sequence-specific DNA binding
NWF24_33300	COG2186	Transcriptional regulator
NWF24_33305	COG2271	Major facilitator Superfamily
NWF24_33310	COG2084	Dehydrogenase
NWF24_33315	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NWF24_33320	COG3395	kinase activity
NWF24_33325	COG0235	Class ii aldolase
NWF24_33330	COG3622	Belongs to the hyi family
NWF24_33340	COG0251	oxidation-reduction process
NWF24_33370	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NWF24_33390	COG0477	Major facilitator Superfamily
NWF24_33395	COG2814	Major facilitator Superfamily
NWF24_33400	COG0765	amino acid transport
NWF24_33430	COG1522	sequence-specific DNA binding
NWF24_33440	COG1862	Preprotein translocase
NWF24_33445	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NWF24_33450	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NWF24_33460	COG2922	Belongs to the Smg family
NWF24_33465	COG0758	DNA mediated transformation
NWF24_33470	COG1652	LysM domain
NWF24_33475	COG0242	peptide deformylase activity
NWF24_33485	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NWF24_33500	COG3181	Tripartite tricarboxylate transporter family receptor
NWF24_33530	COG0583	DNA-binding transcription factor activity
NWF24_33535	COG0126	phosphoglycerate kinase activity
NWF24_33540	COG0469	pyruvate kinase activity
NWF24_33545	COG2515	1-aminocyclopropane-1-carboxylate deaminase
NWF24_33550	COG1522	sequence-specific DNA binding
NWF24_33565	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
NWF24_33585	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NWF24_33590	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
NWF24_33595	COG0009	L-threonylcarbamoyladenylate synthase
NWF24_33605	COG2027	D-alanyl-D-alanine carboxypeptidase
NWF24_33610	COG0494	nUDIX hydrolase
NWF24_33615	COG1349	DNA-binding transcription factor activity
NWF24_33620	COG1214	PFAM Peptidase M22, glycoprotease
NWF24_33635	COG0284	orotidine-5'-phosphate decarboxylase activity
NWF24_33690	COG0343	queuine tRNA-ribosyltransferase activity
NWF24_33695	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
NWF24_33700	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NWF24_33705	COG1280	lysine exporter protein (LysE YggA)
NWF24_33730	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
NWF24_33735	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
NWF24_33740	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
NWF24_33745	COG4770	biotin carboxylase activity
NWF24_33755	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NWF24_33780	COG1414	Transcriptional regulator
NWF24_33790	COG1024	Enoyl-CoA hydratase
NWF24_33795	COG0045	succinate-CoA ligase (ADP-forming) activity
NWF24_33805	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NWF24_33845	COG1960	acyl-CoA dehydrogenase activity
NWF24_33855	COG0431	NADPH-dependent FMN reductase
NWF24_33885	COG0477	Major facilitator Superfamily
NWF24_33905	COG1012	belongs to the aldehyde dehydrogenase family
NWF24_33925	COG1802	Transcriptional regulator
NWF24_33940	COG0783	Belongs to the Dps family
NWF24_33945	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
NWF24_33965	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NWF24_33970	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NWF24_33975	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NWF24_33980	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NWF24_33985	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NWF24_33990	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NWF24_33995	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NWF24_34000	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NWF24_34005	COG1841	ribosomal large subunit assembly
NWF24_34010	COG0200	Binds to the 23S rRNA
NWF24_34015	COG0201	protein transport
NWF24_34020	COG0257	Belongs to the bacterial ribosomal protein bL36 family
NWF24_34025	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NWF24_34030	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NWF24_34035	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NWF24_34040	COG0202	RNA polymerase activity
NWF24_34045	COG0203	ribosomal protein L17
NWF24_34075	COG1960	acyl-CoA dehydrogenase activity
NWF24_34080	COG1024	Enoyl-CoA hydratase
NWF24_34095	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
NWF24_34110	COG0583	DNA-binding transcription factor activity
NWF24_34115	COG1028	Short-chain dehydrogenase reductase Sdr