locus-tag	class	description
H7F36_00005	COG3459	Glycosyltransferase 36 associated
H7F36_00025	COG3275	phosphorelay sensor kinase activity
H7F36_00030	COG0165	Argininosuccinate lyase
H7F36_00075	COG2807	transmembrane transport
H7F36_00080	COG1797	cobyrinic acid a,c-diamide synthase activity
H7F36_00100	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
H7F36_00135	COG2099	Precorrin-6x reductase
H7F36_00150	COG2875	Belongs to the precorrin methyltransferase family
H7F36_00205	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
H7F36_00215	COG1304	FMN binding
H7F36_00235	COG0477	Major facilitator Superfamily
H7F36_00250	COG2226	methyltransferase
H7F36_00265	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
H7F36_00285	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
H7F36_00285	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
H7F36_00300	COG0525	valine-tRNA ligase activity
H7F36_00315	COG0425	Belongs to the sulfur carrier protein TusA family
H7F36_00320	COG2816	NAD+ diphosphatase activity
H7F36_00355	COG0411	ABC transporter
H7F36_00395	COG0559	Belongs to the binding-protein-dependent transport system permease family
H7F36_00400	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
H7F36_00405	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
H7F36_00410	COG1674	ftsk spoiiie
H7F36_00420	COG0492	ferredoxin-NADP+ reductase activity
H7F36_00425	COG0227	Belongs to the bacterial ribosomal protein bL28 family
H7F36_00430	COG0267	Belongs to the bacterial ribosomal protein bL33 family
H7F36_00440	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
H7F36_00440	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
H7F36_00450	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
H7F36_00455	COG1960	acyl-CoA dehydrogenase activity
H7F36_00465	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
H7F36_00475	COG0196	riboflavin kinase activity
H7F36_00485	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
H7F36_00490	COG1283	sodium-dependent phosphate transmembrane transporter activity
H7F36_00500	COG0583	DNA-binding transcription factor activity
H7F36_00515	COG1028	Short-chain dehydrogenase reductase Sdr
H7F36_00530	COG3181	Tripartite tricarboxylate transporter family receptor
H7F36_00545	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
H7F36_00550	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
H7F36_00560	COG0084	hydrolase, TatD family'
H7F36_00565	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H7F36_00570	COG0714	Associated with various cellular activities
H7F36_00580	COG2304	oxidoreductase activity
H7F36_00585	COG1028	Short-chain dehydrogenase reductase Sdr
H7F36_00590	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
H7F36_00595	COG1737	Transcriptional regulator
H7F36_00620	COG0601	transmembrane transport
H7F36_00630	COG0251	oxidation-reduction process
H7F36_00650	COG1136	(ABC) transporter
H7F36_00655	COG4591	ABC-type transport system involved in lipoprotein release permease component
H7F36_00665	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
H7F36_00690	COG0831	urea catabolic process
H7F36_00700	COG0832	Belongs to the urease beta subunit family
H7F36_00705	COG0804	urea catabolic process
H7F36_00720	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
H7F36_00725	COG0830	nickel cation binding
H7F36_00730	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
H7F36_00770	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
H7F36_00790	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
H7F36_00800	COG5001	Diguanylate cyclase
H7F36_00800	COG3300	MHYT domain
H7F36_00815	COG5002	protein histidine kinase activity
H7F36_00815	COG5001	Diguanylate cyclase
H7F36_00815	COG3447	MASE1 domain protein
H7F36_00820	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
H7F36_00825	COG5398	heme oxygenase
H7F36_00830	COG0667	Aldo Keto reductase
H7F36_00835	COG0583	DNA-binding transcription factor activity
H7F36_00840	COG0546	phosphoglycolate phosphatase activity
H7F36_00860	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
H7F36_00865	COG4948	Mandelate Racemase Muconate Lactonizing
H7F36_00880	COG3181	Tripartite tricarboxylate transporter family receptor
H7F36_00885	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
H7F36_00895	COG1175	transmembrane transport
H7F36_00905	COG2186	Transcriptional regulator
H7F36_00910	COG3842	ATPase activity
H7F36_00940	COG0747	negative chemotaxis
H7F36_00945	COG0601	transmembrane transport
H7F36_00950	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H7F36_00955	COG0444	Belongs to the ABC transporter superfamily
H7F36_00960	COG4608	Belongs to the ABC transporter superfamily
H7F36_00965	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
H7F36_01005	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H7F36_01020	COG1177	transmembrane transport
H7F36_01025	COG1176	ABC-type spermidine putrescine transport system, permease component I
H7F36_01030	COG3842	ATPase activity
H7F36_01080	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
H7F36_01100	COG2197	response regulator
H7F36_01155	COG0635	Involved in the biosynthesis of porphyrin-containing compound
H7F36_01160	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
H7F36_01165	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
H7F36_01175	COG0515	serine threonine protein kinase
H7F36_01175	COG2815	serine threonine protein kinase
H7F36_01180	COG1561	YicC-like family, N-terminal region
H7F36_01185	COG0194	GDP metabolic process
H7F36_01190	COG1758	RNA polymerase activity
H7F36_01195	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
H7F36_01215	COG1420	regulation of RNA biosynthetic process
H7F36_01220	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
H7F36_01225	COG0497	DNA recombination
H7F36_01230	COG1660	Displays ATPase and GTPase activities
H7F36_01240	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
H7F36_01245	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
H7F36_01260	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
H7F36_01270	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
H7F36_01275	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
H7F36_01280	COG0193	aminoacyl-tRNA hydrolase activity
H7F36_01290	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
H7F36_01295	COG0601	transmembrane transport
H7F36_01300	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H7F36_01305	COG0444	Belongs to the ABC transporter superfamily
H7F36_01310	COG4608	Belongs to the ABC transporter superfamily
H7F36_01315	COG0747	negative chemotaxis
H7F36_01320	COG0154	amidase activity
H7F36_01330	COG0588	phosphoglycerate mutase activity
H7F36_01345	COG1984	allophanate hydrolase subunit 2
H7F36_01350	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
H7F36_01355	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
H7F36_01360	COG0742	ribosomal rna small subunit methyltransferase
H7F36_01365	COG0612	Peptidase, M16
H7F36_01370	COG0612	Peptidase, M16
H7F36_01385	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
H7F36_01390	COG1999	signal sequence binding
H7F36_01395	COG0109	protoheme IX farnesyltransferase activity
H7F36_01430	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
H7F36_01450	COG2226	methyltransferase
H7F36_01460	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
H7F36_01475	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
H7F36_01475	COG0475	glutathione-regulated potassium exporter activity
H7F36_01485	COG1024	Enoyl-CoA hydratase
H7F36_01520	COG1960	acyl-CoA dehydrogenase activity
H7F36_01530	COG1028	Short-chain dehydrogenase reductase Sdr
H7F36_01540	COG0183	Belongs to the thiolase family
H7F36_01545	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
H7F36_01555	COG1414	Transcriptional regulator
H7F36_01570	COG1028	Short-chain dehydrogenase reductase Sdr
H7F36_01585	COG0410	ABC transporter
H7F36_01590	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
H7F36_01625	COG0583	DNA-binding transcription factor activity
H7F36_01630	COG3485	protocatechuate 3,4-dioxygenase
H7F36_01635	COG3485	protocatechuate 3,4-dioxygenase
H7F36_01645	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
H7F36_01695	COG1051	belongs to the nudix hydrolase family
H7F36_01695	COG1056	cytidyltransferase-related domain
H7F36_01710	COG0438	transferase activity, transferring glycosyl groups
H7F36_01715	COG2144	transferase activity, transferring acyl groups
H7F36_01740	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H7F36_01755	COG0540	Belongs to the ATCase OTCase family
H7F36_01760	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
H7F36_01765	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
H7F36_01770	COG1678	Uncharacterized ACR, COG1678
H7F36_01775	COG0415	Belongs to the DNA photolyase family
H7F36_01820	COG1773	rubredoxin
H7F36_01830	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
H7F36_01840	COG0138	bifunctional purine biosynthesis protein purh
H7F36_01845	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
H7F36_01850	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
H7F36_01855	COG1238	metal cluster binding
H7F36_01865	COG0012	GTP binding
H7F36_01870	COG1879	ABC-type sugar transport system periplasmic component
H7F36_01875	COG1129	ABC transporter
H7F36_01880	COG1172	Belongs to the binding-protein-dependent transport system permease family
H7F36_01885	COG1609	Transcriptional regulator
H7F36_01895	COG1869	D-ribose catabolic process
H7F36_01900	COG3217	Mosc domain protein beta barrel domain protein
H7F36_01900	COG0633	Ferredoxin
H7F36_01905	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H7F36_01925	COG1024	Enoyl-CoA hydratase
H7F36_01955	COG2233	PERMEase
H7F36_01960	COG1953	Uracil, thiamine, allantoin
H7F36_01990	COG0484	heat shock protein binding
H7F36_02005	COG2133	pyrroloquinoline quinone binding
H7F36_02015	COG0534	Mate efflux family protein
H7F36_02035	COG1028	Short-chain dehydrogenase reductase Sdr
H7F36_02045	COG0583	DNA-binding transcription factor activity
H7F36_02105	COG2255	four-way junction helicase activity
H7F36_02110	COG0632	four-way junction helicase activity
H7F36_02120	COG1702	phosphate starvation-inducible protein PhoH
H7F36_02125	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
H7F36_02130	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
H7F36_02145	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
H7F36_02150	COG0739	heme binding
H7F36_02155	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
H7F36_02165	COG0316	Belongs to the HesB IscA family
H7F36_02170	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
H7F36_02175	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
H7F36_02180	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
H7F36_02185	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
H7F36_02200	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
H7F36_02215	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
H7F36_02230	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
H7F36_02235	COG0477	Major facilitator Superfamily
H7F36_02260	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
H7F36_02275	COG1024	Enoyl-CoA hydratase
H7F36_02280	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
H7F36_02285	COG0318	PFAM AMP-dependent synthetase and ligase
H7F36_02290	COG1960	acyl-CoA dehydrogenase activity
H7F36_02305	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
H7F36_02310	COG3012	SEC-C Motif Domain Protein
H7F36_02315	COG1960	acyl-CoA dehydrogenase activity
H7F36_02325	COG0183	Belongs to the thiolase family
H7F36_02330	COG0288	reversible hydration of carbon dioxide
H7F36_02335	COG0789	Transcriptional regulator
H7F36_02370	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
H7F36_02380	COG0751	glycine-tRNA ligase activity
H7F36_02385	COG0752	glycyl-tRNA synthetase alpha subunit
H7F36_02420	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H7F36_02430	COG0251	oxidation-reduction process
H7F36_02435	COG0815	Transfers the fatty acyl group on membrane lipoproteins
H7F36_02440	COG4535	Mg2 and Co2 transporter CorC
H7F36_02465	COG3046	protein related to deoxyribodipyrimidine photolyase
H7F36_02470	COG0415	Belongs to the DNA photolyase family
H7F36_02500	COG0488	(ABC) transporter
H7F36_02505	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H7F36_02530	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H7F36_02535	COG0625	glutathione transferase activity
H7F36_02540	COG0384	phenazine biosynthesis protein PhzF
H7F36_02550	COG1280	lysine exporter protein (LysE YggA)
H7F36_02555	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
H7F36_02565	COG0588	phosphoglycerate mutase activity
H7F36_02605	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
H7F36_02625	COG1028	Short-chain dehydrogenase reductase Sdr
H7F36_02645	COG4232	protein-disulfide reductase activity
H7F36_02650	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H7F36_02660	COG1902	pentaerythritol trinitrate reductase activity
H7F36_02665	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
H7F36_02670	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
H7F36_02700	COG0679	Auxin Efflux Carrier
H7F36_02705	COG0210	DNA helicase
H7F36_02740	COG0582	viral genome integration into host DNA
H7F36_02920	COG2204	response regulator
H7F36_02925	COG5000	phosphorelay sensor kinase activity
H7F36_02945	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
H7F36_02950	COG0085	RNA polymerase activity
H7F36_02955	COG0222	ribosome binding
H7F36_02960	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
H7F36_02965	COG0081	regulation of translation
H7F36_02970	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
H7F36_02980	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
H7F36_02990	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
H7F36_03010	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
H7F36_03015	COG0134	indole-3-glycerol-phosphate synthase activity
H7F36_03020	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
H7F36_03030	COG0512	Glutamine amidotransferase of anthranilate synthase
H7F36_03165	COG0515	serine threonine protein kinase
H7F36_03235	COG0625	glutathione transferase activity
H7F36_03240	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
H7F36_03255	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
H7F36_03310	COG5002	protein histidine kinase activity
H7F36_03315	COG0745	RESPONSE REGULATOR receiver
H7F36_03325	COG2205	protein histidine kinase activity
H7F36_03325	COG2202	Pas domain
H7F36_03330	COG0784	Response regulator, receiver
H7F36_03370	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
H7F36_03375	COG2967	ApaG domain
H7F36_03385	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
H7F36_03395	COG3548	integral membrane protein
H7F36_03400	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
H7F36_03405	COG1546	Belongs to the CinA family
H7F36_03450	COG3318	Belongs to the UPF0149 family
H7F36_03450	COG3012	SEC-C Motif Domain Protein
H7F36_03455	COG0069	glutamate synthase activity
H7F36_03470	COG1335	isochorismatase
H7F36_03480	COG2205	protein histidine kinase activity
H7F36_03480	COG0784	Response regulator, receiver
H7F36_03485	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
H7F36_03490	COG1137	ATPase activity
H7F36_03500	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
H7F36_03510	COG0018	arginyl-trna synthetase
H7F36_03530	COG1215	transferase activity, transferring glycosyl groups
H7F36_03535	COG0583	DNA-binding transcription factor activity
H7F36_03540	COG1804	L-carnitine dehydratase bile acid-inducible protein F
H7F36_03545	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
H7F36_03555	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
H7F36_03560	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
H7F36_03570	COG2197	response regulator
H7F36_03575	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
H7F36_03580	COG3657	addiction module killer protein
H7F36_03590	COG1987	bacterial-type flagellum assembly
H7F36_03605	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
H7F36_03630	COG1157	protein secretion by the type III secretion system
H7F36_03645	COG1766	The M ring may be actively involved in energy transduction
H7F36_03650	COG1677	Flagellar hook-basal body complex protein FliE
H7F36_03700	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
H7F36_03730	COG1815	bacterial-type flagellum-dependent cell motility
H7F36_03735	COG1558	bacterial-type flagellum-dependent cell motility
H7F36_03740	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
H7F36_03745	COG1749	Flagellar hook protein flgE
H7F36_03750	COG4787	bacterial-type flagellum-dependent cell motility
H7F36_03760	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
H7F36_03765	COG1706	bacterial-type flagellum-dependent cell motility
H7F36_03770	COG3951	Flagellar rod assembly protein muramidase FlgJ
H7F36_03770	COG1705	Flagellar rod assembly protein muramidase FlgJ
H7F36_03775	COG1256	bacterial-type flagellum assembly
H7F36_03790	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
H7F36_03795	COG0183	Belongs to the thiolase family
H7F36_03800	COG1024	Enoyl-CoA hydratase
H7F36_03805	COG0205	6-phosphofructokinase activity
H7F36_03820	COG2814	Major facilitator Superfamily
H7F36_03825	COG0121	glutamine amidotransferase
H7F36_03840	COG0189	ligase activity
H7F36_03845	COG3135	benzoate transporter
H7F36_03860	COG3158	transport of potassium into the cell
H7F36_03870	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
H7F36_03885	COG0495	leucyl-tRNA aminoacylation
H7F36_03890	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
H7F36_03900	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
H7F36_03905	COG0297	glycogen (starch) synthase activity
H7F36_03910	COG0058	SHG alpha-glucan phosphorylase activity
H7F36_03925	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
H7F36_03930	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
H7F36_03935	COG0735	belongs to the Fur family
H7F36_03940	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
H7F36_03950	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
H7F36_03960	COG0598	Magnesium transport protein CorA
H7F36_03970	COG0747	negative chemotaxis
H7F36_03975	COG4608	Belongs to the ABC transporter superfamily
H7F36_03980	COG0444	Belongs to the ABC transporter superfamily
H7F36_03985	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H7F36_03990	COG0601	transmembrane transport
H7F36_03995	COG0318	PFAM AMP-dependent synthetase and ligase
H7F36_04015	COG0745	RESPONSE REGULATOR receiver
H7F36_04025	COG2202	Pas domain
H7F36_04025	COG2205	protein histidine kinase activity
H7F36_04035	COG0318	PFAM AMP-dependent synthetase and ligase
H7F36_04040	COG0482	sulfurtransferase activity
H7F36_04045	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H7F36_04055	COG0629	single-stranded DNA binding
H7F36_04070	COG0747	negative chemotaxis
H7F36_04080	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H7F36_04090	COG4608	Belongs to the ABC transporter superfamily
H7F36_04100	COG1609	Transcriptional regulator
H7F36_04110	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H7F36_04120	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
H7F36_04125	COG0747	negative chemotaxis
H7F36_04130	COG0601	transmembrane transport
H7F36_04135	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H7F36_04140	COG0444	Belongs to the ABC transporter superfamily
H7F36_04145	COG4608	Belongs to the ABC transporter superfamily
H7F36_04150	COG1228	amidohydrolase
H7F36_04160	COG0697	spore germination
H7F36_04180	COG1129	ABC transporter
H7F36_04195	COG1946	Acyl-CoA thioesterase
H7F36_04200	COG1858	cytochrome C peroxidase
H7F36_04230	COG3300	MHYT domain
H7F36_04230	COG5001	Diguanylate cyclase
H7F36_04235	COG3639	organic phosphonate transmembrane transporter activity
H7F36_04240	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
H7F36_04245	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
H7F36_04250	COG3454	Phosphonate metabolism
H7F36_04255	COG4778	phosphonate C-P lyase system protein PhnL
H7F36_04260	COG4107	phosphonate C-P lyase system protein PhnK
H7F36_04265	COG3627	carbon phosphorus lyase activity
H7F36_04270	COG3626	phosphonate metabolism
H7F36_04280	COG3624	Phosphonate C-P lyase system protein PhnG
H7F36_04285	COG1609	Transcriptional regulator
H7F36_04290	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
H7F36_04295	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
H7F36_04345	COG0446	pyridine nucleotide-disulphide oxidoreductase
H7F36_04375	COG0179	Fumarylacetoacetate (FAA) hydrolase
H7F36_04380	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
H7F36_04410	COG0604	alcohol dehydrogenase
H7F36_04410	COG1028	Short-chain dehydrogenase reductase Sdr
H7F36_04410	COG3321	synthase
H7F36_04415	COG1609	Transcriptional regulator
H7F36_04420	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
H7F36_04425	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
H7F36_04475	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H7F36_04480	COG2151	metal-sulfur cluster biosynthetic enzyme
H7F36_04485	COG3396	Phenylacetate-CoA oxygenase
H7F36_04490	COG3460	Phenylacetate-CoA oxygenase
H7F36_04495	COG3396	Phenylacetate-CoA oxygenase
H7F36_04505	COG2050	protein possibly involved in aromatic compounds catabolism
H7F36_04510	COG1024	Enoyl-CoA hydratase
H7F36_04520	COG1309	transcriptional regulator
H7F36_04535	COG0284	orotidine-5'-phosphate decarboxylase activity
H7F36_04550	COG1214	PFAM Peptidase M22, glycoprotease
H7F36_04555	COG2027	D-alanyl-D-alanine carboxypeptidase
H7F36_04560	COG0009	L-threonylcarbamoyladenylate synthase
H7F36_04565	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
H7F36_04570	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
H7F36_04575	COG3118	belongs to the thioredoxin family
H7F36_04585	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
H7F36_04590	COG3588	fructose-bisphosphate aldolase
H7F36_04600	COG0469	pyruvate kinase activity
H7F36_04605	COG0126	phosphoglycerate kinase activity
H7F36_04620	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
H7F36_04630	COG0242	peptide deformylase activity
H7F36_04640	COG0758	DNA mediated transformation
H7F36_04645	COG2922	Belongs to the Smg family
H7F36_04655	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
H7F36_04660	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
H7F36_04665	COG1862	Preprotein translocase
H7F36_04675	COG1522	sequence-specific DNA binding
H7F36_04680	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
H7F36_04695	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
H7F36_04700	COG2814	Major facilitator Superfamily
H7F36_04705	COG2084	Dehydrogenase
H7F36_04710	COG3850	Histidine kinase
H7F36_04710	COG2205	protein histidine kinase activity
H7F36_04710	COG4999	Histidine kinase
H7F36_04710	COG3437	response regulator, receiver
H7F36_04715	COG4251	negative regulation of phosphorylation
H7F36_04715	COG5001	Diguanylate cyclase
H7F36_04715	COG3706	GGDEF domain
H7F36_04715	COG2203	Gaf domain
H7F36_04725	COG1215	transferase activity, transferring glycosyl groups
H7F36_04730	COG1215	transferase activity, transferring glycosyl groups
H7F36_04735	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
H7F36_04740	COG0457	Tetratricopeptide repeat
H7F36_04750	COG3468	outer membrane autotransporter barrel domain protein
H7F36_04785	COG3210	domain, Protein
H7F36_04790	COG2831	hemolysin activation secretion protein
H7F36_04805	COG3047	cAMP biosynthetic process
H7F36_04805	COG2885	chlorophyll binding
H7F36_04810	COG4566	intracellular signal transduction
H7F36_04825	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
H7F36_04845	COG0625	glutathione transferase activity
H7F36_04850	COG4269	membrane
H7F36_04865	COG4681	YaeQ
H7F36_04880	COG0861	Integral membrane protein TerC family
H7F36_04890	COG1950	PFAM Membrane protein of
H7F36_04895	COG4783	chaperone-mediated protein folding
H7F36_04900	COG0315	cyclic pyranopterin monophosphate synthase activity
H7F36_05000	COG0631	protein serine/threonine phosphatase activity
H7F36_05005	COG0861	Integral membrane protein TerC family
H7F36_05010	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
H7F36_05015	COG0045	succinate-CoA ligase (ADP-forming) activity
H7F36_05020	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
H7F36_05030	COG2137	regulation of response to DNA damage stimulus
H7F36_05035	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
H7F36_05050	COG0642	Histidine kinase
H7F36_05060	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
H7F36_05060	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
H7F36_05080	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
H7F36_05085	COG1070	Carbohydrate kinase
H7F36_05100	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
H7F36_05105	COG0513	Belongs to the DEAD box helicase family
H7F36_05130	COG0783	Belongs to the Dps family
H7F36_05140	COG0154	amidase activity
H7F36_05145	COG1802	Transcriptional regulator
H7F36_05160	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
H7F36_05165	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
H7F36_05190	COG2094	Belongs to the DNA glycosylase MPG family
H7F36_05205	COG0210	DNA helicase
H7F36_05210	COG1047	Peptidyl-prolyl cis-trans
H7F36_05220	COG1742	UPF0060 membrane protein
H7F36_05245	COG2900	Belongs to the SlyX family
H7F36_05255	COG1914	H( )-stimulated, divalent metal cation uptake system
H7F36_05270	COG5000	phosphorelay sensor kinase activity
H7F36_05270	COG3279	Response regulator of the LytR AlgR family
H7F36_05310	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
H7F36_05325	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
H7F36_05330	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
H7F36_05335	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
H7F36_05345	COG0006	proline dipeptidase activity
H7F36_05355	COG1172	Belongs to the binding-protein-dependent transport system permease family
H7F36_05365	COG1129	ABC transporter
H7F36_05370	COG1172	Belongs to the binding-protein-dependent transport system permease family
H7F36_05375	COG2376	Dihydroxyacetone kinase
H7F36_05395	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
H7F36_05415	COG0280	phosphate acetyltransferase
H7F36_05415	COG0281	malic enzyme
H7F36_05430	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
H7F36_05435	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
H7F36_05440	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
H7F36_05450	COG1385	rRNA (uridine-N3-)-methyltransferase activity
H7F36_05480	COG3622	Belongs to the hyi family
H7F36_05485	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
H7F36_05490	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
H7F36_05495	COG0724	RNA recognition motif
H7F36_05500	COG0300	oxidoreductase activity
H7F36_05510	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
H7F36_05535	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
H7F36_05535	COG2066	Belongs to the glutaminase family
H7F36_05540	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
H7F36_05545	COG0706	membrane insertase activity
H7F36_05550	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
H7F36_05555	COG0594	ribonuclease P activity
H7F36_05560	COG0230	Belongs to the bacterial ribosomal protein bL34 family
H7F36_05565	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
H7F36_05585	COG0598	Magnesium transport protein CorA
H7F36_05595	COG1408	metallophosphoesterase
H7F36_05615	COG0392	lysyltransferase activity
H7F36_05625	COG3568	Endonuclease Exonuclease Phosphatase
H7F36_05655	COG3833	ABC-type maltose transport systems, permease component
H7F36_05660	COG1176	ABC-type spermidine putrescine transport system, permease component I
H7F36_05670	COG3842	ATPase activity
H7F36_05675	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
H7F36_05695	COG4452	Inner membrane protein CreD
H7F36_05705	COG2205	protein histidine kinase activity
H7F36_05710	COG0745	RESPONSE REGULATOR receiver
H7F36_05715	COG0789	Transcriptional regulator
H7F36_05720	COG2217	Heavy metal translocating P-type atpase
H7F36_05725	COG2217	Heavy metal translocating P-type atpase
H7F36_05735	COG0667	Aldo Keto reductase
H7F36_05750	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H7F36_05760	COG0745	RESPONSE REGULATOR receiver
H7F36_05765	COG0642	Histidine kinase
H7F36_05770	COG1902	pentaerythritol trinitrate reductase activity
H7F36_05780	COG0625	glutathione transferase activity
H7F36_05785	COG5487	UPF0391 membrane protein
H7F36_05790	COG0445	tRNA wobble uridine modification
H7F36_05795	COG0357	Ribosomal RNA small subunit methyltransferase G
H7F36_05815	COG1475	DNA binding
H7F36_05820	COG0277	FAD linked oxidase domain protein
H7F36_05825	COG2096	Adenosyltransferase
H7F36_05845	COG1079	Belongs to the binding-protein-dependent transport system permease family
H7F36_05855	COG3845	ABC transporter
H7F36_05875	COG1309	transcriptional regulator
H7F36_05880	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H7F36_05885	COG0778	Nitroreductase
H7F36_05890	COG2267	carboxylic ester hydrolase activity
H7F36_05895	COG0251	oxidation-reduction process
H7F36_05900	COG1335	isochorismatase
H7F36_05905	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H7F36_05910	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
H7F36_05920	COG0850	regulation of cytokinetic process
H7F36_05930	COG2050	protein possibly involved in aromatic compounds catabolism
H7F36_05975	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
H7F36_06000	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
H7F36_06015	COG1129	ABC transporter
H7F36_06020	COG1172	Belongs to the binding-protein-dependent transport system permease family
H7F36_06035	COG1012	belongs to the aldehyde dehydrogenase family
H7F36_06040	COG1950	PFAM Membrane protein of
H7F36_06050	COG0217	transcriptional regulatory protein
H7F36_06055	COG4221	oxidoreductase activity
H7F36_06060	COG0583	DNA-binding transcription factor activity
H7F36_06065	COG1960	acyl-CoA dehydrogenase activity
H7F36_06070	COG1804	L-carnitine dehydratase bile acid-inducible protein F
H7F36_06100	COG2066	Belongs to the glutaminase family
H7F36_06115	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H7F36_06120	COG0700	Nucleoside recognition
H7F36_06125	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H7F36_06130	COG3540	Alkaline phosphatase
H7F36_06155	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
H7F36_06165	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
H7F36_06170	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
H7F36_06180	COG0514	ATP-dependent DNA helicase (RecQ)
H7F36_06190	COG2358	TRAP transporter, solute receptor (TAXI family
H7F36_06195	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H7F36_06205	COG2188	Transcriptional regulator
H7F36_06210	COG2986	histidine ammonia-lyase
H7F36_06215	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
H7F36_06220	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H7F36_06225	COG0765	amino acid transport
H7F36_06235	COG0583	DNA-binding transcription factor activity
H7F36_06250	COG1228	amidohydrolase
H7F36_06265	COG2267	carboxylic ester hydrolase activity
H7F36_06280	COG0583	DNA-binding transcription factor activity
H7F36_06290	COG1199	ATP-dependent helicase activity
H7F36_06295	COG1410	methionine synthase
H7F36_06295	COG0646	methionine synthase
H7F36_06325	COG1309	transcriptional regulator
H7F36_06365	COG0411	ABC transporter
H7F36_06375	COG1335	isochorismatase
H7F36_06380	COG2080	2 iron, 2 sulfur cluster binding
H7F36_06385	COG2010	Cytochrome c
H7F36_06385	COG1529	Aldehyde oxidase and xanthine dehydrogenase
H7F36_06395	COG0606	chelatase, subunit chli
H7F36_06405	COG0347	Belongs to the P(II) protein family
H7F36_06410	COG0004	ammonium transporteR
H7F36_06420	COG0277	FAD linked oxidase domain protein
H7F36_06425	COG0247	lactate metabolic process
H7F36_06450	COG0386	Belongs to the glutathione peroxidase family
H7F36_06455	COG0477	Major facilitator Superfamily
H7F36_06460	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
H7F36_06465	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
H7F36_06490	COG2974	May be involved in recombination
H7F36_06525	COG0745	RESPONSE REGULATOR receiver
H7F36_06530	COG0579	oxidoreductase
H7F36_06545	COG2223	nitrite transmembrane transporter activity
H7F36_06565	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H7F36_06570	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H7F36_06605	COG1079	Belongs to the binding-protein-dependent transport system permease family
H7F36_06610	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
H7F36_06615	COG1335	isochorismatase
H7F36_06620	COG3845	ABC transporter
H7F36_06640	COG1335	isochorismatase
H7F36_06670	COG0708	Exodeoxyribonuclease III
H7F36_06675	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
H7F36_06685	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
H7F36_06690	COG0154	amidase activity
H7F36_06695	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
H7F36_06700	COG1077	Cell shape determining protein MreB Mrl
H7F36_06715	COG0768	penicillin binding
H7F36_06725	COG0004	ammonium transporteR
H7F36_06750	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
H7F36_06755	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
H7F36_06770	COG2095	MarC family integral membrane protein
H7F36_06775	COG1028	Short-chain dehydrogenase reductase Sdr
H7F36_06785	COG0412	Dienelactone hydrolase
H7F36_06790	COG0583	DNA-binding transcription factor activity
H7F36_06800	COG0598	Magnesium transport protein CorA
H7F36_06810	COG1981	membrane
H7F36_06820	COG3411	Ferredoxin
H7F36_06825	COG2945	thiolester hydrolase activity
H7F36_06830	COG1686	Belongs to the peptidase S11 family
H7F36_06835	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
H7F36_06840	COG0049	tRNA binding
H7F36_06845	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
H7F36_06850	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
H7F36_06855	COG0051	transcription antitermination factor activity, RNA binding
H7F36_06870	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
H7F36_06875	COG0088	Forms part of the polypeptide exit tunnel
H7F36_06880	COG0089	rRNA binding
H7F36_06885	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
H7F36_06890	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
H7F36_06895	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
H7F36_06900	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
H7F36_06905	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
H7F36_06910	COG0255	Belongs to the universal ribosomal protein uL29 family
H7F36_06915	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
H7F36_06920	COG0678	peroxiredoxin activity
H7F36_06930	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H7F36_06945	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
H7F36_06950	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
H7F36_06970	COG0745	RESPONSE REGULATOR receiver
H7F36_06975	COG3850	Histidine kinase
H7F36_06975	COG5002	protein histidine kinase activity
H7F36_06980	COG2130	NADP-dependent
H7F36_06995	COG1942	4-Oxalocrotonate Tautomerase
H7F36_07005	COG0318	PFAM AMP-dependent synthetase and ligase
H7F36_07010	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
H7F36_07015	COG0321	lipoyl(octanoyl) transferase activity
H7F36_07020	COG2921	Belongs to the UPF0250 family
H7F36_07025	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
H7F36_07035	COG0356	it plays a direct role in the translocation of protons across the membrane
H7F36_07045	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
H7F36_07050	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
H7F36_07055	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
H7F36_07060	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
H7F36_07065	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
H7F36_07070	COG0355	proton-transporting ATP synthase activity, rotational mechanism
H7F36_07085	COG1172	Belongs to the binding-protein-dependent transport system permease family
H7F36_07090	COG1879	ABC-type sugar transport system periplasmic component
H7F36_07095	COG0673	inositol 2-dehydrogenase activity
H7F36_07105	COG1793	dna ligase
H7F36_07105	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
H7F36_07110	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
H7F36_07110	COG1793	dna ligase
H7F36_07120	COG1201	RNA secondary structure unwinding
H7F36_07130	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
H7F36_07195	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H7F36_07200	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H7F36_07215	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H7F36_07255	COG2132	Multicopper oxidase
H7F36_07275	COG1262	PFAM Formylglycine-generating sulfatase enzyme
H7F36_07285	COG0640	Transcriptional regulator
H7F36_07310	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
H7F36_07315	COG0792	nuclease activity
H7F36_07320	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
H7F36_07330	COG2084	Dehydrogenase
H7F36_07350	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
H7F36_07365	COG0010	Belongs to the arginase family
H7F36_07395	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
H7F36_07395	COG2124	cytochrome p450
H7F36_07405	COG0439	Biotin carboxylase
H7F36_07420	COG1346	cytolysis
H7F36_07425	COG1380	Effector of murein hydrolase LrgA
H7F36_07430	COG0277	FAD linked oxidase domain protein
H7F36_07440	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
H7F36_07465	COG0501	Belongs to the peptidase M48B family
H7F36_07565	COG0343	queuine tRNA-ribosyltransferase activity
H7F36_07575	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
H7F36_07580	COG1090	epimerase
H7F36_07585	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
H7F36_07595	COG0783	Belongs to the Dps family
H7F36_07600	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
H7F36_07615	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
H7F36_07620	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
H7F36_07625	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
H7F36_07630	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
H7F36_07635	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
H7F36_07640	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
H7F36_07645	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
H7F36_07650	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
H7F36_07655	COG1841	ribosomal large subunit assembly
H7F36_07660	COG0200	Binds to the 23S rRNA
H7F36_07665	COG0201	protein transport
H7F36_07670	COG0257	Belongs to the bacterial ribosomal protein bL36 family
H7F36_07675	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
H7F36_07680	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
H7F36_07685	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
H7F36_07690	COG0202	RNA polymerase activity
H7F36_07695	COG0203	ribosomal protein L17
H7F36_07715	COG1960	acyl-CoA dehydrogenase activity
H7F36_07720	COG1024	Enoyl-CoA hydratase
H7F36_07735	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
H7F36_07750	COG0022	dehydrogenase e1 component
H7F36_07755	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
H7F36_07790	COG0318	PFAM AMP-dependent synthetase and ligase
H7F36_07820	COG1022	Amp-dependent synthetase and ligase
H7F36_07825	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H7F36_07885	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
H7F36_07890	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
H7F36_07900	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
H7F36_07905	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
H7F36_07910	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
H7F36_07935	COG2205	protein histidine kinase activity
H7F36_07940	COG0745	RESPONSE REGULATOR receiver
H7F36_07950	COG4213	ABC transporter substrate-binding protein
H7F36_07955	COG1129	ABC transporter
H7F36_07960	COG1172	Belongs to the binding-protein-dependent transport system permease family
H7F36_07965	COG1172	Belongs to the binding-protein-dependent transport system permease family
H7F36_07970	COG1063	alcohol dehydrogenase
H7F36_07995	COG3485	protocatechuate 3,4-dioxygenase
H7F36_08025	COG0596	Alpha beta hydrolase
H7F36_08030	COG2205	protein histidine kinase activity
H7F36_08040	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
H7F36_08055	COG1187	pseudouridine synthase activity
H7F36_08065	COG0702	epimerase
H7F36_08070	COG0583	DNA-binding transcription factor activity
H7F36_08110	COG0642	Histidine kinase
H7F36_08120	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
H7F36_08125	COG1840	ABC-type Fe3 transport system, periplasmic component
H7F36_08130	COG0326	Molecular chaperone. Has ATPase activity
H7F36_08145	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
H7F36_08155	COG1764	response to oxidative stress
H7F36_08160	COG1846	Transcriptional regulator
H7F36_08175	COG1250	3-hydroxyacyl-CoA dehydrogenase
H7F36_08180	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
H7F36_08185	COG0657	acetylesterase activity
H7F36_08190	COG0724	RNA recognition motif
H7F36_08200	COG0023	Translation Initiation Factor
H7F36_08205	COG0513	Belongs to the DEAD box helicase family
H7F36_08220	COG0842	Transport permease protein
H7F36_08225	COG1131	(ABC) transporter
H7F36_08230	COG0583	DNA-binding transcription factor activity
H7F36_08235	COG0625	glutathione transferase activity
H7F36_08245	COG0640	Transcriptional regulator
H7F36_08255	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
H7F36_08280	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
H7F36_08290	COG1473	amidohydrolase
H7F36_08295	COG0584	glycerophosphoryl diester phosphodiesterase
H7F36_08300	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
H7F36_08305	COG2733	membrane
H7F36_08310	COG0243	molybdopterin cofactor binding
H7F36_08375	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
H7F36_08405	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
H7F36_08410	COG0463	Glycosyl transferase, family 2
H7F36_08435	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
H7F36_08455	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
H7F36_08475	COG0662	Cupin 2, conserved barrel domain protein
H7F36_08475	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
H7F36_08480	COG2755	lipolytic protein G-D-S-L family
H7F36_08480	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
H7F36_08485	COG0438	transferase activity, transferring glycosyl groups
H7F36_08485	COG1216	Glycosyl transferase, family 2
H7F36_08505	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
H7F36_08510	COG1309	transcriptional regulator
H7F36_08515	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
H7F36_08525	COG1172	Belongs to the binding-protein-dependent transport system permease family
H7F36_08530	COG1172	Belongs to the binding-protein-dependent transport system permease family
H7F36_08535	COG1129	ABC transporter
H7F36_08540	COG1879	ABC-type sugar transport system periplasmic component
H7F36_08545	COG2721	sulfolactate sulfo-lyase activity
H7F36_08555	COG1028	Short-chain dehydrogenase reductase Sdr
H7F36_08560	COG1028	Short-chain dehydrogenase reductase Sdr
H7F36_08565	COG0179	Fumarylacetoacetate (FAA) hydrolase
H7F36_08570	COG0765	amino acid transport
H7F36_08575	COG0765	amino acid transport
H7F36_08590	COG4948	Mandelate Racemase Muconate Lactonizing
H7F36_08595	COG2188	Transcriptional regulator
H7F36_08630	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
H7F36_08635	COG0066	3-isopropylmalate dehydratase activity
H7F36_08655	COG1053	succinate dehydrogenase
H7F36_08665	COG0583	DNA-binding transcription factor activity
H7F36_08670	COG4221	oxidoreductase activity
H7F36_08680	COG1960	acyl-CoA dehydrogenase activity
H7F36_08690	COG1024	Enoyl-CoA hydratase
H7F36_08690	COG1250	3-hydroxyacyl-CoA dehydrogenase
H7F36_08695	COG2852	Protein conserved in bacteria
H7F36_08700	COG0183	Belongs to the thiolase family
H7F36_08715	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
H7F36_08745	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H7F36_08780	COG1607	acyl-coa hydrolase
H7F36_08785	COG5265	(ABC) transporter
H7F36_08790	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
H7F36_08795	COG0583	DNA-binding transcription factor activity
H7F36_08800	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H7F36_08805	COG0765	amino acid transport
H7F36_08810	COG0765	amino acid transport
H7F36_08815	COG1126	abc transporter atp-binding protein
H7F36_08825	COG0154	amidase activity
H7F36_08830	COG0444	Belongs to the ABC transporter superfamily
H7F36_08835	COG4608	Belongs to the ABC transporter superfamily
H7F36_08840	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H7F36_08850	COG0747	negative chemotaxis
H7F36_08855	COG0418	dihydroorotase activity
H7F36_08870	COG0501	Belongs to the peptidase M48B family
H7F36_08880	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H7F36_08885	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
H7F36_08915	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
H7F36_08930	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
H7F36_08955	COG1116	anion transmembrane transporter activity
H7F36_08960	COG0154	amidase activity
H7F36_08980	COG0523	cobalamin synthesis protein
H7F36_09000	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
H7F36_09005	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
H7F36_09010	COG2001	Belongs to the MraZ family
H7F36_09015	COG0275	rRNA processing
H7F36_09020	COG3116	cell division
H7F36_09030	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
H7F36_09035	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
H7F36_09040	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
H7F36_09045	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
H7F36_09050	COG0772	Belongs to the SEDS family
H7F36_09055	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
H7F36_09060	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
H7F36_09065	COG1181	Belongs to the D-alanine--D-alanine ligase family
H7F36_09070	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
H7F36_09085	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
H7F36_09100	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
H7F36_09105	COG4589	Belongs to the CDS family
H7F36_09115	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
H7F36_09120	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
H7F36_09135	COG3150	esterase
H7F36_09145	COG2197	response regulator
H7F36_09155	COG0772	Belongs to the SEDS family
H7F36_09160	COG0312	modulator of DNA gyrase
H7F36_09165	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
H7F36_09175	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
H7F36_09185	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H7F36_09190	COG0511	ligase activity, forming carbon-carbon bonds
H7F36_09195	COG0439	Biotin carboxylase
H7F36_09200	COG2264	protein methyltransferase activity
H7F36_09210	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H7F36_09220	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
H7F36_09250	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
H7F36_09255	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
H7F36_09260	COG2943	transferase activity, transferring hexosyl groups
H7F36_09265	COG2204	response regulator
H7F36_09275	COG2205	protein histidine kinase activity
H7F36_09280	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
H7F36_09295	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H7F36_09335	COG0037	tRNA processing
H7F36_09345	COG1028	Short-chain dehydrogenase reductase Sdr
H7F36_09380	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
H7F36_09390	COG0617	tRNA 3'-terminal CCA addition
H7F36_09405	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
H7F36_09410	COG0583	DNA-binding transcription factor activity
H7F36_09425	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
H7F36_09430	COG1522	sequence-specific DNA binding
H7F36_09440	COG0745	RESPONSE REGULATOR receiver
H7F36_09450	COG2205	protein histidine kinase activity
H7F36_09460	COG3386	PFAM SMP-30 Gluconolaconase
H7F36_09470	COG1012	belongs to the aldehyde dehydrogenase family
H7F36_09475	COG1879	ABC-type sugar transport system periplasmic component
H7F36_09480	COG4213	ABC transporter substrate-binding protein
H7F36_09490	COG4214	carbohydrate transport
H7F36_09500	COG1172	Belongs to the binding-protein-dependent transport system permease family
H7F36_09505	COG1172	Belongs to the binding-protein-dependent transport system permease family
H7F36_09520	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
H7F36_09520	COG0189	ligase activity
H7F36_09525	COG0189	ligase activity
H7F36_09525	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
H7F36_09530	COG1132	(ABC) transporter
H7F36_09540	COG2076	Multidrug Resistance protein
H7F36_09545	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
H7F36_09545	COG0546	phosphoglycolate phosphatase activity
H7F36_09555	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
H7F36_09560	COG4178	(ABC) transporter
H7F36_09565	COG0137	argininosuccinate synthase activity
H7F36_09575	COG1459	type II secretion system
H7F36_09635	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
H7F36_09645	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
H7F36_09660	COG1473	amidohydrolase
H7F36_09665	COG0747	negative chemotaxis
H7F36_09670	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H7F36_09675	COG0444	Belongs to the ABC transporter superfamily
H7F36_09680	COG4608	Belongs to the ABC transporter superfamily
H7F36_09700	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
H7F36_09715	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
H7F36_09720	COG1840	ABC-type Fe3 transport system, periplasmic component
H7F36_09730	COG3842	ATPase activity
H7F36_09745	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
H7F36_09750	COG0166	Belongs to the GPI family
H7F36_09765	COG1175	transmembrane transport
H7F36_09770	COG0395	ABC-type sugar transport system, permease component
H7F36_09775	COG3842	ATPase activity
H7F36_09780	COG0246	Mannitol dehydrogenase
H7F36_09790	COG2207	Transcriptional regulator
H7F36_09790	COG4753	response regulator
H7F36_09795	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
H7F36_09810	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
H7F36_09815	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
H7F36_09820	COG0745	RESPONSE REGULATOR receiver
H7F36_09825	COG5002	protein histidine kinase activity
H7F36_09830	COG0459	protein refolding
H7F36_09835	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
H7F36_09845	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
H7F36_09850	COG0366	Alpha amylase catalytic
H7F36_09855	COG0366	Alpha amylase catalytic
H7F36_09860	COG0668	transmembrane transport
H7F36_09865	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
H7F36_09870	COG1640	4-alpha-glucanotransferase
H7F36_09875	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H7F36_09880	COG4772	TonB-dependent receptor
H7F36_09895	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
H7F36_09905	COG1560	Kdo2-lipid A biosynthetic process
H7F36_09915	COG0218	Necessary for normal cell division and for the maintenance of normal septation
H7F36_09930	COG1333	cytochrome c biogenesis protein
H7F36_09935	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
H7F36_09940	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
H7F36_09945	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
H7F36_09950	COG0019	diaminopimelate decarboxylase activity
H7F36_09960	COG1965	Belongs to the frataxin family
H7F36_09995	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
H7F36_10000	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
H7F36_10005	COG0232	Belongs to the dGTPase family. Type 2 subfamily
H7F36_10030	COG0069	glutamate synthase activity
H7F36_10030	COG0067	glutamate synthase
H7F36_10030	COG0070	glutamate synthase
H7F36_10040	COG1127	ABC transporter
H7F36_10045	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
H7F36_10050	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
H7F36_10070	COG1131	(ABC) transporter
H7F36_10075	COG0842	Transport permease protein
H7F36_10080	COG5007	Belongs to the BolA IbaG family
H7F36_10085	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
H7F36_10090	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
H7F36_10105	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
H7F36_10110	COG0131	Imidazoleglycerol-phosphate dehydratase
H7F36_10120	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
H7F36_10130	COG0107	imidazoleglycerol-phosphate synthase activity
H7F36_10135	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
H7F36_10140	COG0140	phosphoribosyl-ATP diphosphatase activity
H7F36_10150	COG0537	adenosine 5'-monophosphoramidase activity
H7F36_10155	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
H7F36_10160	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
H7F36_10165	COG0805	protein transport
H7F36_10175	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
H7F36_10180	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
H7F36_10185	COG1970	mechanosensitive ion channel activity
H7F36_10190	COG0723	plastoquinol--plastocyanin reductase activity
H7F36_10195	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
H7F36_10200	COG2857	Cytochrome c1
H7F36_10205	COG0625	glutathione transferase activity
H7F36_10210	COG2969	positive regulation of protein catabolic process
H7F36_10220	COG1309	transcriptional regulator
H7F36_10245	COG0653	protein targeting
H7F36_10250	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
H7F36_10260	COG0494	nUDIX hydrolase
H7F36_10265	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
H7F36_10270	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
H7F36_10285	COG1696	Membrane protein involved in D-alanine export
H7F36_10295	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
H7F36_10315	COG0142	geranyltranstransferase activity
H7F36_10320	COG0261	This protein binds to 23S rRNA in the presence of protein L20
H7F36_10325	COG0211	Belongs to the bacterial ribosomal protein bL27 family
H7F36_10330	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
H7F36_10335	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
H7F36_10345	COG0494	nUDIX hydrolase
H7F36_10350	COG0442	prolyl-tRNA aminoacylation
H7F36_10360	COG1253	flavin adenine dinucleotide binding
H7F36_10375	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
H7F36_10380	COG2890	protein-(glutamine-N5) methyltransferase activity
H7F36_10385	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
H7F36_10390	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
H7F36_10400	COG1196	nuclear chromosome segregation
H7F36_10400	COG3264	Mechanosensitive ion channel
H7F36_10405	COG0584	glycerophosphoryl diester phosphodiesterase
H7F36_10410	COG3842	ATPase activity
H7F36_10415	COG0395	ABC-type sugar transport system, permease component
H7F36_10425	COG1653	transport
H7F36_10430	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
H7F36_10445	COG2226	methyltransferase
H7F36_10460	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
H7F36_10465	COG4145	pantothenate transmembrane transporter activity
H7F36_10480	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
H7F36_10535	COG5487	UPF0391 membrane protein
H7F36_10545	COG2197	response regulator
H7F36_10550	COG2982	Protein involved in outer membrane biogenesis
H7F36_10555	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
H7F36_10560	COG0793	Belongs to the peptidase S41A family
H7F36_10565	COG0588	phosphoglycerate mutase activity
H7F36_10570	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
H7F36_10580	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
H7F36_10585	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
H7F36_10610	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H7F36_10610	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H7F36_10615	COG0473	3-isopropylmalate dehydrogenase activity
H7F36_10620	COG3132	Protein of unknown function, DUF480
H7F36_10625	COG0489	protein tyrosine kinase activity
H7F36_10630	COG0583	DNA-binding transcription factor activity
H7F36_10635	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
H7F36_10640	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
H7F36_10645	COG3639	organic phosphonate transmembrane transporter activity
H7F36_10650	COG3639	organic phosphonate transmembrane transporter activity
H7F36_10660	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
H7F36_10695	COG1529	Aldehyde oxidase and xanthine dehydrogenase
H7F36_10700	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
H7F36_10705	COG2080	2 iron, 2 sulfur cluster binding
H7F36_10720	COG3276	selenocysteine insertion sequence binding
H7F36_10750	COG2864	formate dehydrogenase
H7F36_10755	COG0437	4 iron, 4 sulfur cluster binding
H7F36_10770	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
H7F36_10790	COG2003	Belongs to the UPF0758 family
H7F36_10795	COG1047	Peptidyl-prolyl cis-trans
H7F36_10800	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
H7F36_10805	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
H7F36_10810	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
H7F36_10820	COG5002	protein histidine kinase activity
H7F36_10825	COG2197	response regulator
H7F36_10830	COG0180	Tryptophanyl-tRNA synthetase
H7F36_10835	COG1994	Peptidase M50
H7F36_10840	COG0009	L-threonylcarbamoyladenylate synthase
H7F36_10850	COG0613	PHP domain protein
H7F36_10860	COG0306	phosphate transporter
H7F36_10865	COG3181	Tripartite tricarboxylate transporter family receptor
H7F36_10905	COG2814	Major facilitator Superfamily
H7F36_10915	COG0667	Aldo Keto reductase
H7F36_10920	COG2201	protein-glutamate methylesterase activity
H7F36_10935	COG2814	Major facilitator Superfamily
H7F36_10960	COG0318	PFAM AMP-dependent synthetase and ligase
H7F36_10975	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
H7F36_11000	COG0829	nickel cation binding
H7F36_11010	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H7F36_11030	COG0402	S-adenosylhomocysteine deaminase activity
H7F36_11035	COG0628	permease
H7F36_11045	COG2233	PERMEase
H7F36_11070	COG2186	Transcriptional regulator
H7F36_11075	COG2351	hydroxyisourate hydrolase activity
H7F36_11095	COG0318	PFAM AMP-dependent synthetase and ligase
H7F36_11110	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
H7F36_11120	COG1802	Transcriptional regulator
H7F36_11125	COG0671	phosphoesterase, PA-phosphatase related
H7F36_11145	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
H7F36_11160	COG0642	Histidine kinase
H7F36_11170	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H7F36_11200	COG1028	Short-chain dehydrogenase reductase Sdr
H7F36_11220	COG0628	permease
H7F36_11260	COG1529	Aldehyde oxidase and xanthine dehydrogenase
H7F36_11270	COG3845	ABC transporter
H7F36_11275	COG4603	Belongs to the binding-protein-dependent transport system permease family
H7F36_11290	COG2814	Major facilitator Superfamily
H7F36_11295	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
H7F36_11305	COG0318	PFAM AMP-dependent synthetase and ligase
H7F36_11310	COG0402	S-adenosylhomocysteine deaminase activity
H7F36_11315	COG0717	Belongs to the dCTP deaminase family
H7F36_11325	COG2321	neutral zinc metallopeptidase
H7F36_11330	COG0513	Belongs to the DEAD box helicase family
H7F36_11335	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
H7F36_11340	COG1253	flavin adenine dinucleotide binding
H7F36_11365	COG1126	abc transporter atp-binding protein
H7F36_11375	COG2207	Transcriptional regulator
H7F36_11380	COG0251	oxidation-reduction process
H7F36_11385	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
H7F36_11390	COG1960	acyl-CoA dehydrogenase activity
H7F36_11395	COG0439	Biotin carboxylase
H7F36_11400	COG1024	Enoyl-CoA hydratase
H7F36_11410	COG1250	3-hydroxyacyl-CoA dehydrogenase
H7F36_11410	COG1024	Enoyl-CoA hydratase
H7F36_11420	COG1802	Transcriptional regulator
H7F36_11465	COG0463	Glycosyl transferase, family 2
H7F36_11485	COG3038	cytochrome b561
H7F36_11490	COG0390	transport system, permease component
H7F36_11495	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
H7F36_11500	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H7F36_11520	COG0642	Histidine kinase
H7F36_11535	COG2890	protein-(glutamine-N5) methyltransferase activity
H7F36_11540	COG1181	Belongs to the D-alanine--D-alanine ligase family
H7F36_11540	COG2918	glutathione biosynthetic process
H7F36_11550	COG2814	Major facilitator Superfamily
H7F36_11560	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
H7F36_11565	COG0308	aminopeptidase N
H7F36_11570	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
H7F36_11590	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
H7F36_11595	COG0784	Response regulator, receiver
H7F36_11595	COG2198	Histidine kinase
H7F36_11595	COG2205	protein histidine kinase activity
H7F36_11605	COG0667	Aldo Keto reductase
H7F36_11610	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
H7F36_11615	COG0251	oxidation-reduction process
H7F36_11620	COG3577	Aspartyl protease
H7F36_11625	COG1666	GTP binding
H7F36_11630	COG0812	UDP-N-acetylmuramate dehydrogenase activity
H7F36_11640	COG3123	guanosine phosphorylase activity
H7F36_11660	COG1393	Belongs to the ArsC family
H7F36_11665	COG0285	dihydrofolate synthase activity
H7F36_11670	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
H7F36_11675	COG1286	toxin biosynthetic process
H7F36_11690	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
H7F36_11720	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
H7F36_11740	COG2268	Band 7 protein
H7F36_11745	COG5564	TIM-barrel signal transduction protein
H7F36_11760	COG0683	leucine binding
H7F36_11780	COG1228	amidohydrolase
H7F36_11785	COG0596	Alpha beta hydrolase
H7F36_11790	COG0179	Fumarylacetoacetate (FAA) hydrolase
H7F36_11805	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
H7F36_11805	COG0506	proline dehydrogenase activity
H7F36_11805	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
H7F36_11810	COG1028	Short-chain dehydrogenase reductase Sdr
H7F36_11825	COG0516	GMP reductase activity
H7F36_11830	COG0210	DNA helicase
H7F36_11840	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
H7F36_11855	COG0412	Dienelactone hydrolase
H7F36_11870	COG3064	Membrane
H7F36_11890	COG1722	exodeoxyribonuclease VII activity
H7F36_11895	COG0142	geranyltranstransferase activity
H7F36_11900	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
H7F36_11905	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
H7F36_11920	COG1262	PFAM Formylglycine-generating sulfatase enzyme
H7F36_11925	COG0477	Major facilitator Superfamily
H7F36_11930	COG0784	Response regulator, receiver
H7F36_11930	COG4191	Histidine kinase
H7F36_11945	COG3383	formate dehydrogenase (NAD+) activity
H7F36_11965	COG1064	alcohol dehydrogenase
H7F36_11970	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
H7F36_11975	COG4149	molybdate abc transporter
H7F36_11980	COG0725	ABC transporter, periplasmic molybdate-binding protein
H7F36_12000	COG2205	protein histidine kinase activity
H7F36_12040	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
H7F36_12040	COG3608	succinylglutamate desuccinylase aspartoacylase
H7F36_12045	COG1522	sequence-specific DNA binding
H7F36_12055	COG1360	Flagellar Motor Protein
H7F36_12070	COG0129	dihydroxy-acid dehydratase activity
H7F36_12075	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
H7F36_12080	COG2186	Transcriptional regulator
H7F36_12085	COG3842	ATPase activity
H7F36_12100	COG3833	ABC-type maltose transport systems, permease component
H7F36_12110	COG1320	monovalent cation:proton antiporter activity
H7F36_12115	COG2212	antiporter activity
H7F36_12125	COG0651	ATP synthesis coupled electron transport
H7F36_12130	COG1006	Multisubunit Na H antiporter MnhC subunit
H7F36_12135	COG2111	Na H antiporter
H7F36_12135	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
H7F36_12140	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
H7F36_12150	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
H7F36_12170	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
H7F36_12175	COG0287	Prephenate dehydrogenase
H7F36_12180	COG1605	Chorismate mutase
H7F36_12180	COG0077	Prephenate dehydratase
H7F36_12185	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
H7F36_12205	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
H7F36_12220	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
H7F36_12220	COG4797	methyltransferase
H7F36_12230	COG1187	pseudouridine synthase activity
H7F36_12255	COG1546	Belongs to the CinA family
H7F36_12255	COG1058	Belongs to the CinA family
H7F36_12260	COG0174	glutamine synthetase
H7F36_12270	COG3852	Histidine kinase
H7F36_12310	COG0708	Exodeoxyribonuclease III
H7F36_12320	COG2376	Dihydroxyacetone kinase
H7F36_12325	COG1461	Dihydroxyacetone kinase
H7F36_12330	COG3842	ATPase activity
H7F36_12335	COG3842	ATPase activity
H7F36_12345	COG0395	ABC-type sugar transport system, permease component
H7F36_12350	COG1175	transmembrane transport
H7F36_12370	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
H7F36_12390	COG0277	FAD linked oxidase domain protein
H7F36_12400	COG1295	ribonuclease BN
H7F36_12405	COG3118	belongs to the thioredoxin family
H7F36_12410	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
H7F36_12420	COG0517	IMP dehydrogenase activity
H7F36_12440	COG1042	CoA-binding domain protein
H7F36_12440	COG0045	succinate-CoA ligase (ADP-forming) activity
H7F36_12440	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
H7F36_12445	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
H7F36_12460	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
H7F36_12475	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
H7F36_12490	COG2719	SpoVR family
H7F36_12495	COG2718	Belongs to the UPF0229 family
H7F36_12500	COG2766	serine protein kinase
H7F36_12505	COG0484	heat shock protein binding
H7F36_12510	COG0443	Heat shock 70 kDa protein
H7F36_12515	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
H7F36_12530	COG0688	phosphatidylethanolamine metabolic process
H7F36_12535	COG2706	6-phosphogluconolactonase activity
H7F36_12550	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
H7F36_12555	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
H7F36_12565	COG1126	abc transporter atp-binding protein
H7F36_12570	COG0765	amino acid transport
H7F36_12575	COG0765	amino acid transport
H7F36_12580	COG2186	Transcriptional regulator
H7F36_12585	COG3181	Tripartite tricarboxylate transporter family receptor
H7F36_12590	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H7F36_12610	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
H7F36_12610	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
H7F36_12615	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H7F36_12625	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
H7F36_12675	COG2010	Cytochrome c
H7F36_12675	COG1529	Aldehyde oxidase and xanthine dehydrogenase
H7F36_12680	COG2863	cytochrome
H7F36_12690	COG0697	spore germination
H7F36_12725	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
H7F36_12740	COG1309	transcriptional regulator
H7F36_12745	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
H7F36_12765	COG0129	dihydroxy-acid dehydratase activity
H7F36_12780	COG0259	pyridoxamine-phosphate oxidase activity
H7F36_12785	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
H7F36_12810	COG0800	Aldolase
H7F36_12820	COG0346	lactoylglutathione lyase activity
H7F36_12850	COG0235	Class ii aldolase
H7F36_12855	COG0800	Aldolase
H7F36_12860	COG3734	2-keto-3-deoxy-galactonokinase
H7F36_12870	COG0513	Belongs to the DEAD box helicase family
H7F36_12875	COG0488	(ABC) transporter
H7F36_12880	COG2133	pyrroloquinoline quinone binding
H7F36_12890	COG3191	aminopeptidase activity
H7F36_12895	COG1069	ribulokinase activity
H7F36_12905	COG4214	carbohydrate transport
H7F36_12925	COG4774	siderophore transport
H7F36_12930	COG3128	pkhd-type hydroxylase
H7F36_12935	COG1971	Probably functions as a manganese efflux pump
H7F36_12950	COG0318	PFAM AMP-dependent synthetase and ligase
H7F36_12960	COG1252	NADH dehydrogenase
H7F36_12965	COG1262	PFAM Formylglycine-generating sulfatase enzyme
H7F36_12970	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
H7F36_12990	COG0564	pseudouridine synthase activity
H7F36_13000	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H7F36_13005	COG4628	conserved protein (DUF2132)
H7F36_13025	COG2354	Protein conserved in bacteria
H7F36_13030	COG2271	Major facilitator Superfamily
H7F36_13050	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
H7F36_13055	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
H7F36_13065	COG2084	Dehydrogenase
H7F36_13080	COG0400	carboxylic ester hydrolase activity
H7F36_13085	COG2918	glutathione biosynthetic process
H7F36_13095	COG1028	Short-chain dehydrogenase reductase Sdr
H7F36_13105	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
H7F36_13170	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
H7F36_13175	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
H7F36_13180	COG4770	biotin carboxylase activity
H7F36_13190	COG1280	lysine exporter protein (LysE YggA)
H7F36_13230	COG1028	Short-chain dehydrogenase reductase Sdr
H7F36_13245	COG0515	serine threonine protein kinase
H7F36_13245	COG2815	serine threonine protein kinase
H7F36_13250	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
H7F36_13275	COG2972	Histidine kinase
H7F36_13325	COG2205	protein histidine kinase activity
H7F36_13330	COG0745	RESPONSE REGULATOR receiver
H7F36_13340	COG1459	type II secretion system
H7F36_13430	COG5295	Hep Hag repeat protein
H7F36_13475	COG1968	undecaprenyl-diphosphatase activity
H7F36_13500	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
H7F36_13510	COG2375	cellular response to nickel ion
H7F36_13515	COG1695	Transcriptional regulator
H7F36_13525	COG1289	transmembrane transporter activity
H7F36_13530	COG0483	inositol monophosphate 1-phosphatase activity
H7F36_13540	COG0521	Mo-molybdopterin cofactor biosynthetic process
H7F36_13545	COG3028	Belongs to the UPF0307 family
H7F36_13550	COG0312	modulator of DNA gyrase
H7F36_13560	COG0828	Belongs to the bacterial ribosomal protein bS21 family
H7F36_13565	COG5002	protein histidine kinase activity
H7F36_13575	COG3210	domain, Protein
H7F36_13585	COG0745	RESPONSE REGULATOR receiver
H7F36_13595	COG2081	HI0933 family
H7F36_13600	COG0791	NLP P60 protein
H7F36_13615	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
H7F36_13620	COG0243	molybdopterin cofactor binding
H7F36_13630	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H7F36_13635	COG1116	anion transmembrane transporter activity
H7F36_13640	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H7F36_13645	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H7F36_13650	COG3707	response regulator
H7F36_13655	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
H7F36_13670	COG0436	Aminotransferase
H7F36_13675	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
H7F36_13680	COG1185	polyribonucleotide nucleotidyltransferase activity
H7F36_13685	COG3321	synthase
H7F36_13685	COG0604	alcohol dehydrogenase
H7F36_13685	COG1028	Short-chain dehydrogenase reductase Sdr
H7F36_13690	COG0149	triose-phosphate isomerase activity
H7F36_13705	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
H7F36_13710	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
H7F36_13715	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
H7F36_13720	COG0649	NAD binding
H7F36_13735	COG1034	ATP synthesis coupled electron transport
H7F36_13740	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
H7F36_13745	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
H7F36_13755	COG0713	ATP synthesis coupled electron transport
H7F36_13770	COG1007	ATP synthesis coupled electron transport
H7F36_13780	COG0494	nUDIX hydrolase
H7F36_13790	COG1132	(ABC) transporter
H7F36_13795	COG1846	Transcriptional regulator
H7F36_13800	COG1538	Outer membrane efflux protein
H7F36_13805	COG1566	PFAM secretion protein HlyD family protein
H7F36_13820	COG1126	abc transporter atp-binding protein
H7F36_13860	COG0235	Class ii aldolase
H7F36_13865	COG3395	kinase activity
H7F36_13870	COG4181	ATPase activity
H7F36_13875	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
H7F36_13880	COG2814	Major facilitator Superfamily
H7F36_13890	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
H7F36_13910	COG0601	transmembrane transport
H7F36_13920	COG0444	Belongs to the ABC transporter superfamily
H7F36_13935	COG0586	Pfam SNARE associated Golgi protein
H7F36_13945	COG0860	N-Acetylmuramoyl-L-alanine amidase
H7F36_13950	COG0802	atpase or kinase
H7F36_13955	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
H7F36_13960	COG3181	Tripartite tricarboxylate transporter family receptor
H7F36_13965	COG4974	Belongs to the 'phage' integrase family
H7F36_13970	COG2833	Protein of unknown function (DUF455)
H7F36_13980	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
H7F36_13995	COG3201	nicotinamide mononucleotide transporter
H7F36_14000	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
H7F36_14005	COG0148	phosphopyruvate hydratase activity
H7F36_14015	COG2877	3-deoxy-8-phosphooctulonate synthase activity
H7F36_14020	COG0504	CTP synthase activity
H7F36_14025	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
H7F36_14035	COG0756	dUTP diphosphatase activity
H7F36_14045	COG1047	Peptidyl-prolyl cis-trans
H7F36_14050	COG2850	peptidyl-arginine hydroxylation
H7F36_14065	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
H7F36_14070	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
H7F36_14075	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H7F36_14100	COG1196	nuclear chromosome segregation
H7F36_14100	COG0741	lytic transglycosylase activity
H7F36_14100	COG0739	heme binding
H7F36_14140	COG0431	NADPH-dependent FMN reductase
H7F36_14150	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
H7F36_14170	COG3210	domain, Protein
H7F36_14175	COG2831	hemolysin activation secretion protein
H7F36_14215	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
H7F36_14220	COG3239	Fatty acid desaturase
H7F36_14230	COG0601	transmembrane transport
H7F36_14235	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H7F36_14250	COG1454	alcohol dehydrogenase
H7F36_14255	COG0243	molybdopterin cofactor binding
H7F36_14260	COG1028	Short-chain dehydrogenase reductase Sdr
H7F36_14265	COG0583	DNA-binding transcription factor activity
H7F36_14270	COG1172	Belongs to the binding-protein-dependent transport system permease family
H7F36_14305	COG0765	amino acid transport
H7F36_14310	COG0765	amino acid transport
H7F36_14315	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H7F36_14320	COG1126	abc transporter atp-binding protein
H7F36_14330	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H7F36_14340	COG1609	Transcriptional regulator
H7F36_14390	COG2308	Evidence 4 Homologs of previously reported genes of
H7F36_14405	COG2308	Evidence 4 Homologs of previously reported genes of
H7F36_14420	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
H7F36_14435	COG3842	ATPase activity
H7F36_14440	COG3842	ATPase activity
H7F36_14450	COG0395	ABC-type sugar transport system, permease component
H7F36_14480	COG2951	lytic endotransglycosylase activity
H7F36_14495	COG0714	Associated with various cellular activities
H7F36_14505	COG3264	Mechanosensitive ion channel
H7F36_14505	COG1511	domain protein
H7F36_14520	COG1960	acyl-CoA dehydrogenase activity
H7F36_14535	COG4988	ABC transporter
H7F36_14540	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
H7F36_14545	COG1271	oxidase subunit
H7F36_14550	COG1294	oxidase, subunit
H7F36_14570	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
H7F36_14585	COG1414	Transcriptional regulator
H7F36_14590	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
H7F36_14595	COG0477	Major facilitator Superfamily
H7F36_14605	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
H7F36_14610	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
H7F36_14615	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
H7F36_14650	COG0583	DNA-binding transcription factor activity
H7F36_14660	COG2271	Major facilitator Superfamily
H7F36_14665	COG2070	2-Nitropropane dioxygenase
H7F36_14675	COG0540	Belongs to the ATCase OTCase family
H7F36_14680	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H7F36_14690	COG1028	Short-chain dehydrogenase reductase Sdr
H7F36_14695	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
H7F36_14695	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
H7F36_14700	COG0509	glycine decarboxylation via glycine cleavage system
H7F36_14705	COG0404	The glycine cleavage system catalyzes the degradation of glycine
H7F36_14710	COG4654	Cytochrome c, class I
H7F36_14800	COG1172	Belongs to the binding-protein-dependent transport system permease family
H7F36_14805	COG1129	ABC transporter
H7F36_14810	COG1879	ABC-type sugar transport system periplasmic component
H7F36_14815	COG1984	allophanate hydrolase subunit 2
H7F36_14825	COG0439	Biotin carboxylase
H7F36_14830	COG0511	ligase activity, forming carbon-carbon bonds
H7F36_14835	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
H7F36_14840	COG0583	DNA-binding transcription factor activity
H7F36_14900	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
H7F36_14910	COG1028	Short-chain dehydrogenase reductase Sdr
H7F36_14920	COG0642	Histidine kinase
H7F36_14945	COG4302	ethanolamine ammonia-lyase activity
H7F36_14950	COG4303	Ethanolamine ammonia lyase large subunit
H7F36_14960	COG0545	Peptidyl-prolyl cis-trans isomerase
H7F36_14985	COG1172	Belongs to the binding-protein-dependent transport system permease family
H7F36_14990	COG1129	ABC transporter
H7F36_15005	COG2197	response regulator
H7F36_15030	COG1804	L-carnitine dehydratase bile acid-inducible protein F
H7F36_15045	COG1960	acyl-CoA dehydrogenase activity
H7F36_15050	COG1024	Enoyl-CoA hydratase
H7F36_15065	COG3181	Tripartite tricarboxylate transporter family receptor
H7F36_15075	COG2818	Glycosylase
H7F36_15095	COG2366	antibiotic biosynthetic process
H7F36_15100	COG1183	phosphatidylcholine synthase activity
H7F36_15105	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
H7F36_15115	COG1132	(ABC) transporter
H7F36_15125	COG3384	dioxygenase
H7F36_15135	COG3038	cytochrome b561
H7F36_15155	COG0587	DNA-directed DNA polymerase activity
H7F36_15185	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H7F36_15190	COG2146	nitrite reductase [NAD(P)H] activity
H7F36_15195	COG2116	formate transmembrane transporter activity
H7F36_15205	COG1072	(Pantothenic acid kinase))
H7F36_15240	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
H7F36_15245	COG0438	transferase activity, transferring glycosyl groups
H7F36_15290	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
H7F36_15295	COG0438	transferase activity, transferring glycosyl groups
H7F36_15330	COG2755	lipolytic protein G-D-S-L family
H7F36_15330	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
H7F36_15360	COG5002	protein histidine kinase activity
H7F36_15360	COG3447	MASE1 domain protein
H7F36_15360	COG5001	Diguanylate cyclase
H7F36_15375	COG0427	acetyl-CoA hydrolase
H7F36_15385	COG0626	cystathionine gamma-synthase activity
H7F36_15400	COG1136	(ABC) transporter
H7F36_15405	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
H7F36_15420	COG0667	Aldo Keto reductase
H7F36_15435	COG1295	ribonuclease BN
H7F36_15450	COG1028	Short-chain dehydrogenase reductase Sdr
H7F36_15455	COG0456	acetyltransferase
H7F36_15455	COG1846	Transcriptional regulator
H7F36_15485	COG0583	DNA-binding transcription factor activity
H7F36_15490	COG0670	Belongs to the BI1 family
H7F36_15505	COG1024	Enoyl-CoA hydratase
H7F36_15510	COG0778	Nitroreductase
H7F36_15510	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
H7F36_15520	COG1716	ATPase activity
H7F36_15565	COG0625	glutathione transferase activity
H7F36_15575	COG1272	protein, Hemolysin III
H7F36_15605	COG0248	Ppx GppA phosphatase
H7F36_15610	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
H7F36_15615	COG0573	inorganic phosphate transmembrane transporter activity
H7F36_15620	COG0581	inorganic phosphate transmembrane transporter activity
H7F36_15625	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
H7F36_15640	COG5002	protein histidine kinase activity
H7F36_15645	COG0534	Mate efflux family protein
H7F36_15655	COG0254	rRNA binding
H7F36_15660	COG0673	inositol 2-dehydrogenase activity
H7F36_15665	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
H7F36_15680	COG1074	ATP-dependent DNA helicase activity
H7F36_15685	COG2081	HI0933 family
H7F36_15695	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
H7F36_15700	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
H7F36_15705	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
H7F36_15710	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H7F36_15720	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H7F36_15725	COG1388	LysM domain
H7F36_15725	COG0741	lytic transglycosylase activity
H7F36_15730	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H7F36_15740	COG0328	RNA-DNA hybrid ribonuclease activity
H7F36_15745	COG0303	'Molybdopterin
H7F36_15750	COG0746	molybdenum cofactor guanylyltransferase activity
H7F36_15755	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
H7F36_15760	COG1012	belongs to the aldehyde dehydrogenase family
H7F36_15770	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H7F36_15785	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
H7F36_15815	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
H7F36_15840	COG0028	Belongs to the TPP enzyme family
H7F36_15850	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
H7F36_15855	COG1183	phosphatidylcholine synthase activity
H7F36_15860	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
H7F36_15865	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
H7F36_15875	COG1414	Transcriptional regulator
H7F36_15880	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
H7F36_15885	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
H7F36_15900	COG1414	Transcriptional regulator
H7F36_15910	COG0642	Histidine kinase
H7F36_15915	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H7F36_15930	COG3971	2-oxopent-4-enoate hydratase activity
H7F36_15935	COG1959	2 iron, 2 sulfur cluster binding
H7F36_15945	COG1012	belongs to the aldehyde dehydrogenase family
H7F36_15950	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H7F36_15955	COG2721	sulfolactate sulfo-lyase activity
H7F36_15965	COG2084	Dehydrogenase
H7F36_15970	COG1609	Transcriptional regulator
H7F36_15995	COG0179	Fumarylacetoacetate (FAA) hydrolase
H7F36_16010	COG1137	ATPase activity
H7F36_16020	COG2951	lytic endotransglycosylase activity
H7F36_16030	COG0028	Belongs to the TPP enzyme family
H7F36_16045	COG1804	L-carnitine dehydratase bile acid-inducible protein F
H7F36_16090	COG1802	Transcriptional regulator
H7F36_16095	COG0235	Class ii aldolase
H7F36_16100	COG3395	kinase activity
H7F36_16145	COG5507	3-demethylubiquinone-9 3-methyltransferase
H7F36_16165	COG0492	ferredoxin-NADP+ reductase activity
H7F36_16170	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
H7F36_16175	COG2895	sulfate adenylyltransferase (ATP) activity
H7F36_16185	COG0175	sulfate reduction
H7F36_16215	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
H7F36_16215	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
H7F36_16220	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
H7F36_16230	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H7F36_16235	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H7F36_16240	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H7F36_16245	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H7F36_16250	COG1116	anion transmembrane transporter activity
H7F36_16270	COG1960	acyl-CoA dehydrogenase activity
H7F36_16295	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
H7F36_16310	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
H7F36_16315	COG1845	cytochrome c oxidase, subunit III
H7F36_16320	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
H7F36_16325	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
H7F36_16330	COG0477	Major facilitator Superfamily
H7F36_16335	COG1045	serine acetyltransferase
H7F36_16340	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
H7F36_16340	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
H7F36_16350	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
H7F36_16360	COG0450	alkyl hydroperoxide reductase
H7F36_16370	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
H7F36_16380	COG4208	sulfate ABC transporter
H7F36_16385	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
H7F36_16390	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
H7F36_16415	COG5001	Diguanylate cyclase
H7F36_16415	COG3300	MHYT domain
H7F36_16430	COG1529	Aldehyde oxidase and xanthine dehydrogenase
H7F36_16430	COG2010	Cytochrome c
H7F36_16440	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
H7F36_16445	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
H7F36_16470	COG1196	nuclear chromosome segregation
H7F36_16480	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
H7F36_16495	COG0242	peptide deformylase activity
H7F36_16500	COG2259	Doxx family
H7F36_16505	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H7F36_16510	COG4597	amino acid ABC transporter
H7F36_16515	COG0765	amino acid transport
H7F36_16530	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
H7F36_16535	COG0024	Methionine aminopeptidase
H7F36_16540	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
H7F36_16540	COG0047	phosphoribosylformylglycinamidine synthase activity
H7F36_16545	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
H7F36_16555	COG2917	probably involved in intracellular septation
H7F36_16560	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
H7F36_16565	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
H7F36_16570	COG0318	PFAM AMP-dependent synthetase and ligase
H7F36_16590	COG0411	ABC transporter
H7F36_16595	COG1131	(ABC) transporter
H7F36_16600	COG1024	Enoyl-CoA hydratase
H7F36_16600	COG1250	3-hydroxyacyl-CoA dehydrogenase
H7F36_16605	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
H7F36_16610	COG0183	Belongs to the thiolase family
H7F36_16615	COG1960	acyl-CoA dehydrogenase activity
H7F36_16640	COG2130	NADP-dependent
H7F36_16645	COG1960	acyl-CoA dehydrogenase activity
H7F36_16680	COG0625	glutathione transferase activity
H7F36_16685	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
H7F36_16700	COG0243	molybdopterin cofactor binding
H7F36_16715	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
H7F36_16730	COG0583	DNA-binding transcription factor activity
H7F36_16740	COG0025	NhaP-type Na H and K H
H7F36_16745	COG2814	Major facilitator Superfamily
H7F36_16750	COG2814	Major facilitator Superfamily
H7F36_16775	COG0765	amino acid transport
H7F36_16790	COG4670	ketone body catabolic process
H7F36_16795	COG1960	acyl-CoA dehydrogenase activity
H7F36_16805	COG1609	Transcriptional regulator
H7F36_16810	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H7F36_16815	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H7F36_16820	COG1126	abc transporter atp-binding protein
H7F36_16825	COG0534	Mate efflux family protein
H7F36_16830	COG2995	paraquat-inducible protein a
H7F36_16835	COG2995	paraquat-inducible protein a
H7F36_16840	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
H7F36_16840	COG3008	intermembrane lipid transfer
H7F36_16860	COG1454	alcohol dehydrogenase
H7F36_16865	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
H7F36_16875	COG1129	ABC transporter
H7F36_16880	COG1172	Belongs to the binding-protein-dependent transport system permease family
H7F36_16885	COG1879	ABC-type sugar transport system periplasmic component
H7F36_16890	COG0693	protein deglycase activity
H7F36_16900	COG2183	response to ionizing radiation
H7F36_16905	COG3550	peptidyl-serine autophosphorylation
H7F36_16925	COG2153	protein acetylation
H7F36_16930	COG0583	DNA-binding transcription factor activity
H7F36_16935	COG2159	amidohydrolase
H7F36_16945	COG3384	dioxygenase
H7F36_16965	COG0354	folic acid binding
H7F36_16970	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
H7F36_16975	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
H7F36_16990	COG0084	hydrolase, TatD family'
H7F36_17020	COG3842	ATPase activity
H7F36_17025	COG1175	transmembrane transport
H7F36_17030	COG0395	ABC-type sugar transport system, permease component
H7F36_17075	COG0277	FAD linked oxidase domain protein
H7F36_17085	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H7F36_17090	COG0601	transmembrane transport
H7F36_17095	COG0747	negative chemotaxis
H7F36_17105	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H7F36_17115	COG0596	Alpha beta hydrolase
H7F36_17130	COG0318	PFAM AMP-dependent synthetase and ligase
H7F36_17140	COG0411	ABC transporter
H7F36_17155	COG4638	Rieske (2fe-2S)
H7F36_17160	COG0683	leucine binding
H7F36_17170	COG0411	ABC transporter
H7F36_17185	COG1028	Short-chain dehydrogenase reductase Sdr
H7F36_17190	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
H7F36_17240	COG0604	alcohol dehydrogenase
H7F36_17245	COG1250	3-hydroxyacyl-CoA dehydrogenase
H7F36_17255	COG3128	pkhd-type hydroxylase
H7F36_17260	COG4774	siderophore transport
H7F36_17275	COG1028	Short-chain dehydrogenase reductase Sdr
H7F36_17280	COG1063	alcohol dehydrogenase
H7F36_17285	COG1609	Transcriptional regulator
H7F36_17290	COG1129	ABC transporter
H7F36_17315	COG0625	glutathione transferase activity
H7F36_17350	COG1028	Short-chain dehydrogenase reductase Sdr
H7F36_17360	COG0628	permease
H7F36_17385	COG1172	Belongs to the binding-protein-dependent transport system permease family
H7F36_17395	COG0066	3-isopropylmalate dehydratase activity
H7F36_17400	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
H7F36_17405	COG0247	lactate metabolic process
H7F36_17405	COG0277	FAD linked oxidase domain protein
H7F36_17460	COG0789	Transcriptional regulator
H7F36_17480	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
H7F36_17490	COG3148	PFAM DTW domain containing protein
H7F36_17505	COG0625	glutathione transferase activity
H7F36_17535	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H7F36_17540	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
H7F36_17550	COG2175	clavaminate synthase activity
H7F36_17595	COG2423	ornithine cyclodeaminase activity
H7F36_17610	COG3447	MASE1 domain protein
H7F36_17610	COG5001	Diguanylate cyclase
H7F36_17610	COG5002	protein histidine kinase activity
H7F36_17615	COG1846	Transcriptional regulator
H7F36_17625	COG2814	Major facilitator Superfamily
H7F36_17635	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
H7F36_17660	COG0667	Aldo Keto reductase
H7F36_17675	COG2814	Major facilitator Superfamily
H7F36_17690	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
H7F36_17710	COG5001	Diguanylate cyclase
H7F36_17715	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
H7F36_17720	COG3265	gluconokinase activity
H7F36_17730	COG1538	Outer membrane efflux protein
H7F36_17745	COG0745	RESPONSE REGULATOR receiver
H7F36_17750	COG2205	protein histidine kinase activity
H7F36_17760	COG4716	Myosin-crossreactive antigen
H7F36_17770	COG4191	Histidine kinase
H7F36_17770	COG0784	Response regulator, receiver
H7F36_17775	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H7F36_17785	COG0589	response to stress
H7F36_17790	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
H7F36_17820	COG1172	Belongs to the binding-protein-dependent transport system permease family
H7F36_17825	COG1879	ABC-type sugar transport system periplasmic component
H7F36_17830	COG1172	Belongs to the binding-protein-dependent transport system permease family
H7F36_17835	COG0318	PFAM AMP-dependent synthetase and ligase
H7F36_17850	COG1619	proteins homologs of microcin C7 resistance protein MccF
H7F36_17865	COG2808	Putative FMN-binding domain
H7F36_17870	COG0518	GMP synthase (glutamine-hydrolyzing) activity
H7F36_17870	COG0519	Catalyzes the synthesis of GMP from XMP
H7F36_17885	COG2914	Belongs to the UPF0125 (RnfH) family
H7F36_17890	COG2867	negative regulation of translational initiation
H7F36_17895	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
H7F36_17900	COG0110	maltose O-acetyltransferase activity
H7F36_17905	COG0438	transferase activity, transferring glycosyl groups
H7F36_17935	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
H7F36_17940	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
H7F36_17945	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
H7F36_17950	COG2251	uridine kinase activity
H7F36_17950	COG0195	Participates in both transcription termination and antitermination
H7F36_17955	COG0779	Required for maturation of 30S ribosomal subunits
H7F36_17960	COG0477	Major facilitator Superfamily
H7F36_17965	COG4172	Belongs to the ABC transporter superfamily
H7F36_17970	COG4239	(ABC) transporter, permease
H7F36_17975	COG4174	ABC transporter (Permease)
H7F36_17985	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
H7F36_17990	COG1793	dna ligase
H7F36_17995	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
H7F36_18015	COG3842	ATPase activity
H7F36_18020	COG1840	ABC-type Fe3 transport system, periplasmic component
H7F36_18025	COG1802	Transcriptional regulator
H7F36_18085	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
H7F36_18095	COG0795	lipopolysaccharide-transporting ATPase activity
H7F36_18105	COG0583	DNA-binding transcription factor activity
H7F36_18110	COG0436	Aminotransferase
H7F36_18120	COG1643	Atp-dependent helicase
H7F36_18135	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
H7F36_18135	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
H7F36_18175	COG2171	N-acyltransferase activity
H7F36_18185	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
H7F36_18190	COG2890	protein-(glutamine-N5) methyltransferase activity
H7F36_18200	COG0488	(ABC) transporter
H7F36_18220	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
H7F36_18230	COG2885	chlorophyll binding
H7F36_18235	COG0823	Involved in the tonB-independent uptake of proteins
H7F36_18240	COG1132	(ABC) transporter
H7F36_18245	COG1530	ribonuclease E activity
H7F36_18250	COG0424	maF-like protein
H7F36_18255	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
H7F36_18260	COG0799	negative regulation of ribosome biogenesis
H7F36_18265	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
H7F36_18270	COG0408	coproporphyrinogen oxidase activity
H7F36_18275	COG0151	Belongs to the GarS family
H7F36_18280	COG0217	transcriptional regulatory protein
H7F36_18320	COG1028	Short-chain dehydrogenase reductase Sdr
H7F36_18370	COG0433	COG0433 Predicted ATPase
H7F36_18400	COG0419	ATPase involved in DNA repair
H7F36_18405	COG0420	3'-5' exonuclease activity
H7F36_18415	COG1595	DNA-templated transcription, initiation
H7F36_18430	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
H7F36_18460	COG1595	DNA-templated transcription, initiation
H7F36_18475	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
H7F36_18480	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
H7F36_18485	COG0402	S-adenosylhomocysteine deaminase activity
H7F36_18500	COG0745	RESPONSE REGULATOR receiver
H7F36_18505	COG0745	RESPONSE REGULATOR receiver
H7F36_18515	COG2925	Exonuclease
H7F36_18520	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H7F36_18525	COG0542	response to heat
H7F36_18530	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
H7F36_18555	COG0811	peptide transport
H7F36_18560	COG0848	biopolymer transport protein
H7F36_18565	COG1663	tetraacyldisaccharide 4'-kinase activity
H7F36_18570	COG2835	tetraacyldisaccharide 4'-kinase activity
H7F36_18575	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
H7F36_18580	COG0563	adenylate kinase activity
H7F36_18590	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
H7F36_18600	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
H7F36_18605	COG2814	Major facilitator Superfamily
H7F36_18615	COG1250	3-hydroxyacyl-CoA dehydrogenase
H7F36_18620	COG1024	Enoyl-CoA hydratase
H7F36_18650	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
H7F36_18655	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
H7F36_18660	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
H7F36_18665	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
H7F36_18670	COG1534	Rna-binding protein
H7F36_18685	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
H7F36_18695	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
H7F36_18700	COG0505	Belongs to the CarA family
H7F36_18705	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
H7F36_18715	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
H7F36_18720	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
H7F36_18725	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
H7F36_18730	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
H7F36_18745	COG0750	zinc metalloprotease
H7F36_18750	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
H7F36_18755	COG0575	Belongs to the CDS family
H7F36_18760	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
H7F36_18765	COG0233	cytoplasmic translational termination
H7F36_18770	COG0528	UMP kinase activity
H7F36_18775	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
H7F36_18780	COG0052	Belongs to the universal ribosomal protein uS2 family
H7F36_18795	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
H7F36_18795	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
H7F36_18800	COG1028	Short-chain dehydrogenase reductase Sdr
H7F36_18805	COG0557	exoribonuclease II activity
H7F36_18815	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
H7F36_18820	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
H7F36_18835	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
H7F36_18865	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
H7F36_18865	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
H7F36_18870	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
H7F36_18870	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
H7F36_18875	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
H7F36_18880	COG0560	Phosphoserine phosphatase
H7F36_18885	COG0783	Belongs to the Dps family
H7F36_18900	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H7F36_18910	COG3550	peptidyl-serine autophosphorylation
H7F36_18915	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
H7F36_18925	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
H7F36_18930	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
H7F36_18935	COG1492	cobalamin metabolic process
H7F36_18950	COG2226	methyltransferase
H7F36_18955	COG1538	Outer membrane efflux protein
H7F36_18965	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H7F36_18970	COG0657	acetylesterase activity
H7F36_19020	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
H7F36_19025	COG0778	Nitroreductase
H7F36_19030	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
H7F36_19035	COG1121	(ABC) transporter
H7F36_19040	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H7F36_19045	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
H7F36_19075	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
H7F36_19080	COG0583	DNA-binding transcription factor activity
H7F36_19085	COG0129	dihydroxy-acid dehydratase activity
H7F36_19095	COG4654	Cytochrome c, class I
H7F36_19105	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
H7F36_19115	COG0114	fumarate hydratase activity
H7F36_19130	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
H7F36_19200	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
H7F36_19215	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H7F36_19225	COG1136	(ABC) transporter
H7F36_19250	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
H7F36_19260	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
H7F36_19265	COG3025	triphosphatase activity
H7F36_19280	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
H7F36_19285	COG0471	metal ion transport
H7F36_19295	COG4585	Histidine kinase
H7F36_19310	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H7F36_19340	COG3278	Belongs to the heme-copper respiratory oxidase family
H7F36_19355	COG0635	Involved in the biosynthesis of porphyrin-containing compound
H7F36_19365	COG1042	CoA-binding domain protein
H7F36_19365	COG0045	succinate-CoA ligase (ADP-forming) activity
H7F36_19365	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
H7F36_19390	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
H7F36_19395	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
H7F36_19400	COG0740	serine-type endopeptidase activity
H7F36_19405	COG0544	peptidyl-prolyl cis-trans isomerase activity
H7F36_19415	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H7F36_19420	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H7F36_19425	COG3158	transport of potassium into the cell
H7F36_19440	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
H7F36_19450	COG1011	Hydrolase
H7F36_19455	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
H7F36_19480	COG1126	abc transporter atp-binding protein
H7F36_19485	COG1126	abc transporter atp-binding protein
H7F36_19495	COG2204	response regulator
H7F36_19560	COG0642	Histidine kinase
H7F36_19575	COG2326	polyphosphate kinase activity
H7F36_19635	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
H7F36_19660	COG0527	aspartate kinase activity
H7F36_19665	COG0037	tRNA processing
H7F36_19670	COG0825	malonyl-CoA metabolic process
H7F36_19680	COG0215	cysteine-tRNA ligase activity
H7F36_19700	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
H7F36_19720	COG0741	lytic transglycosylase activity
H7F36_19725	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
H7F36_19730	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
H7F36_19735	COG4969	Belongs to the N-Me-Phe pilin family
H7F36_19765	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
H7F36_19765	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
H7F36_19780	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
H7F36_19785	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
H7F36_19790	COG0436	Aminotransferase
H7F36_19795	COG0824	Thioesterase
H7F36_19805	COG0848	biopolymer transport protein
H7F36_19820	COG1054	Belongs to the UPF0176 family
H7F36_19830	COG0642	Histidine kinase
H7F36_19845	COG1741	Belongs to the pirin family
H7F36_19855	COG2259	Doxx family
H7F36_19860	COG1741	Belongs to the pirin family
H7F36_19875	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
H7F36_19880	COG0220	tRNA (guanine-N7-)-methyltransferase activity
H7F36_19890	COG0300	oxidoreductase activity
H7F36_19895	COG0456	acetyltransferase
H7F36_19910	COG1686	Belongs to the peptidase S11 family
H7F36_19925	COG3186	Phenylalanine-4-hydroxylase
H7F36_19930	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
H7F36_19955	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
H7F36_19960	COG1960	acyl-CoA dehydrogenase activity
H7F36_19965	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
H7F36_19970	COG3842	ATPase activity
H7F36_19980	COG1176	ABC-type spermidine putrescine transport system, permease component I
H7F36_19995	COG0784	Response regulator, receiver
H7F36_19995	COG5002	protein histidine kinase activity
H7F36_19995	COG2198	Histidine kinase
H7F36_20035	COG2205	protein histidine kinase activity
H7F36_20035	COG0784	Response regulator, receiver
H7F36_20035	COG2198	Histidine kinase
H7F36_20045	COG0583	DNA-binding transcription factor activity
H7F36_20065	COG3038	cytochrome b561
H7F36_20095	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
H7F36_20100	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
H7F36_20105	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
H7F36_20110	COG3842	ATPase activity
H7F36_20120	COG1176	ABC-type spermidine putrescine transport system, permease component I
H7F36_20140	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
H7F36_20145	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
H7F36_20150	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
H7F36_20155	COG0330	HflC and HflK could
H7F36_20160	COG0330	HflC and HflK could
H7F36_20165	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
H7F36_20170	COG1923	regulation of RNA biosynthetic process
H7F36_20175	COG1160	GTP binding
H7F36_20180	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
H7F36_20190	COG0124	histidyl-tRNA synthetase
H7F36_20195	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
H7F36_20215	COG0105	UTP biosynthetic process
H7F36_20220	COG1187	pseudouridine synthase activity
H7F36_20225	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
H7F36_20230	COG0564	pseudouridine synthase activity
H7F36_20240	COG1199	ATP-dependent helicase activity
H7F36_20250	COG0631	protein serine/threonine phosphatase activity
H7F36_20260	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
H7F36_20265	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H7F36_20270	COG0508	dehydrogenase complex catalyzes the overall conversion of
H7F36_20275	COG0567	Dehydrogenase, E1 component
H7F36_20305	COG4221	oxidoreductase activity
H7F36_20315	COG2133	pyrroloquinoline quinone binding
H7F36_20320	COG0791	NLP P60 protein
H7F36_20325	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H7F36_20335	COG0508	dehydrogenase complex catalyzes the overall conversion of
H7F36_20340	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
H7F36_20345	COG4191	Histidine kinase
H7F36_20350	COG4566	intracellular signal transduction
H7F36_20355	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
H7F36_20370	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
H7F36_20375	COG0167	dihydroorotate dehydrogenase activity
H7F36_20400	COG0633	Ferredoxin
H7F36_20405	COG0443	Heat shock 70 kDa protein
H7F36_20410	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
H7F36_20420	COG0822	iron-sulfur transferase activity
H7F36_20425	COG1104	cysteine desulfurase activity
H7F36_20430	COG1959	2 iron, 2 sulfur cluster binding
H7F36_20435	COG0556	nucleotide-excision repair
H7F36_20450	COG2878	Part of a membrane complex involved in electron transport
H7F36_20460	COG4770	biotin carboxylase activity
H7F36_20465	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
H7F36_20470	COG1703	isobutyryl-CoA mutase activity
H7F36_20475	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
H7F36_20475	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
H7F36_20480	COG1802	Transcriptional regulator
H7F36_20485	COG1028	Short-chain dehydrogenase reductase Sdr
H7F36_20495	COG0765	amino acid transport
H7F36_20500	COG1126	abc transporter atp-binding protein
H7F36_20505	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
H7F36_20520	COG1301	dicarboxylic acid transport
H7F36_20525	COG1028	Short-chain dehydrogenase reductase Sdr
H7F36_20535	COG1653	transport
H7F36_20545	COG0395	ABC-type sugar transport system, permease component
H7F36_20560	COG0183	Belongs to the thiolase family
H7F36_20565	COG3243	poly(R)-hydroxyalkanoic acid synthase
H7F36_20595	COG3045	CreA protein
H7F36_20610	COG3485	protocatechuate 3,4-dioxygenase
H7F36_20630	COG1137	ATPase activity
H7F36_20645	COG1012	belongs to the aldehyde dehydrogenase family
H7F36_20695	COG2186	Transcriptional regulator
H7F36_20705	COG1172	Belongs to the binding-protein-dependent transport system permease family
H7F36_20710	COG1172	Belongs to the binding-protein-dependent transport system permease family
H7F36_20715	COG1129	ABC transporter
H7F36_20730	COG0583	DNA-binding transcription factor activity
H7F36_20745	COG0583	DNA-binding transcription factor activity
H7F36_20775	COG0776	regulation of translation
H7F36_20780	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H7F36_20780	COG0072	phenylalanine-tRNA ligase activity
H7F36_20785	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
H7F36_20790	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
H7F36_20795	COG0291	Belongs to the bacterial ribosomal protein bL35 family
H7F36_20800	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
H7F36_20805	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
H7F36_20810	COG2224	Isocitrate lyase
H7F36_20825	COG0028	Belongs to the TPP enzyme family
H7F36_20830	COG1309	transcriptional regulator
H7F36_20860	COG0673	inositol 2-dehydrogenase activity
H7F36_20875	COG3214	Protein conserved in bacteria
H7F36_20885	COG2271	Major facilitator Superfamily
H7F36_20890	COG2814	Major facilitator Superfamily
H7F36_20925	COG0183	Belongs to the thiolase family
H7F36_20935	COG0542	response to heat
H7F36_20940	COG0314	molybdopterin synthase activity
H7F36_20950	COG0303	'Molybdopterin
H7F36_20955	COG1763	Mo-molybdopterin cofactor biosynthetic process
H7F36_20960	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
H7F36_20970	COG0436	Aminotransferase
H7F36_20980	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
H7F36_20985	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
H7F36_20995	COG0359	binds to the 23S rRNA
H7F36_21000	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
H7F36_21010	COG0360	Binds together with S18 to 16S ribosomal RNA
H7F36_21025	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
H7F36_21060	COG1477	protein flavinylation
H7F36_21065	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
H7F36_21095	COG3193	protein, possibly involved in utilization of glycolate and propanediol
H7F36_21100	COG0670	Belongs to the BI1 family
H7F36_21105	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
H7F36_21115	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
H7F36_21120	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
H7F36_21155	COG0473	3-isopropylmalate dehydrogenase activity
H7F36_21160	COG0596	Alpha beta hydrolase
H7F36_21175	COG0322	excinuclease ABC activity
H7F36_21185	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
H7F36_21190	COG1611	Belongs to the LOG family
H7F36_21205	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
H7F36_21215	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
H7F36_21230	COG0824	Thioesterase
H7F36_21245	COG1295	ribonuclease BN
H7F36_21255	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
H7F36_21260	COG2814	Major facilitator Superfamily
H7F36_21265	COG0583	DNA-binding transcription factor activity
H7F36_21270	COG3971	2-oxopent-4-enoate hydratase activity
H7F36_21285	COG0179	Fumarylacetoacetate (FAA) hydrolase
H7F36_21290	COG0351	phosphomethylpyrimidine kinase
H7F36_21310	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
H7F36_21320	COG0791	NLP P60 protein
H7F36_21340	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
H7F36_21350	COG0513	Belongs to the DEAD box helicase family
H7F36_21355	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
H7F36_21365	COG2154	pterin-4-alpha-carbinolamine dehydratase
H7F36_21370	COG1162	GTPase activity
H7F36_21380	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
H7F36_21395	COG0335	large ribosomal subunit rRNA binding
H7F36_21400	COG0336	Belongs to the RNA methyltransferase TrmD family
H7F36_21405	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
H7F36_21410	COG0228	four-way junction DNA binding
H7F36_21425	COG0306	phosphate transporter
H7F36_21430	COG1392	Phosphate transport regulator
H7F36_21435	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
H7F36_21440	COG0617	tRNA 3'-terminal CCA addition
H7F36_21445	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
H7F36_21450	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
H7F36_21460	COG1289	transmembrane transporter activity
H7F36_21475	COG0728	peptidoglycan biosynthetic process
H7F36_21480	COG0268	Binds directly to 16S ribosomal RNA
H7F36_21490	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
H7F36_21495	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
H7F36_21500	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
H7F36_21510	COG3483	tryptophan 2,3-dioxygenase activity
H7F36_21530	COG4942	peptidase
H7F36_21535	COG4804	nuclease activity
H7F36_21540	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H7F36_21560	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
H7F36_21595	COG1049	propionate catabolic process, 2-methylcitrate cycle
H7F36_21610	COG0039	L-malate dehydrogenase activity
H7F36_21615	COG2188	Transcriptional regulator
H7F36_21630	COG1053	succinate dehydrogenase
H7F36_21635	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
H7F36_21640	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
H7F36_21645	COG0372	Belongs to the citrate synthase family
H7F36_21660	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
H7F36_21665	COG0066	3-isopropylmalate dehydratase activity
H7F36_21670	COG0473	3-isopropylmalate dehydrogenase activity
H7F36_21675	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
H7F36_21685	COG0101	tRNA pseudouridine synthase activity
H7F36_21690	COG0135	phosphoribosylanthranilate isomerase activity
H7F36_21695	COG0133	tryptophan synthase activity
H7F36_21700	COG0159	tryptophan synthase activity
H7F36_21705	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
H7F36_21710	COG0762	integral membrane protein
H7F36_21720	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
H7F36_21725	COG0443	Heat shock 70 kDa protein
H7F36_21730	COG1451	nucleotide metabolic process
H7F36_21735	COG1472	Belongs to the glycosyl hydrolase 3 family
H7F36_21740	COG0736	holo-[acyl-carrier-protein] synthase activity
H7F36_21745	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
H7F36_21750	COG1381	Involved in DNA repair and RecF pathway recombination
H7F36_21755	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
H7F36_21760	COG0571	ribonuclease III activity
H7F36_21770	COG0681	Belongs to the peptidase S26 family
H7F36_21775	COG0481	GTPase activity
H7F36_21780	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H7F36_21805	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
H7F36_21810	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H7F36_21815	COG1028	Short-chain dehydrogenase reductase Sdr
H7F36_21820	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
H7F36_21825	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
H7F36_21830	COG0416	fatty acid biosynthetic process
H7F36_21835	COG0333	Belongs to the bacterial ribosomal protein bL32 family
H7F36_21840	COG1399	metal-binding, possibly nucleic acid-binding protein
H7F36_21845	COG0424	maF-like protein
H7F36_21850	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
H7F36_21855	COG2223	nitrite transmembrane transporter activity
H7F36_21860	COG0616	signal peptide processing
H7F36_21880	COG1530	ribonuclease E activity
H7F36_21895	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
H7F36_21900	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
H7F36_21915	COG0438	transferase activity, transferring glycosyl groups
H7F36_21925	COG0297	glycogen (starch) synthase activity
H7F36_21940	COG1596	polysaccharide export
H7F36_21960	COG0181	hydroxymethylbilane synthase activity
H7F36_21965	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle