locus-tag	class	description
H4CHR_00001	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
H4CHR_00002	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
H4CHR_00003	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
H4CHR_00006	ENOG4107RN3	metallophosphoesterase
H4CHR_00008	ENOG41061N2	exported protein
H4CHR_00010	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
H4CHR_00011	ENOG4107UXM	Membrane
H4CHR_00012	ENOG4105DZQ	phospholipase D Transphosphatidylase
H4CHR_00013	ENOG4105X23	Endonuclease Exonuclease phosphatase
H4CHR_00017	ENOG4105EUB	pirin domain protein
H4CHR_00018	ENOG410633P	Hydantoin racemase
H4CHR_00020	ENOG4105F38	ABC transporter, permease
H4CHR_00022	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
H4CHR_00023	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
H4CHR_00027	ENOG4108JQC	penicillin-binding protein 1A
H4CHR_00028	ENOG4105EB3	Histidine kinase
H4CHR_00029	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
H4CHR_00031	ENOG4105C59	p-type ATPase
H4CHR_00033	ENOG4105ECM	Sensor protein basS pmrB
H4CHR_00034	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
H4CHR_00035	ENOG4105CBP	Major Facilitator
H4CHR_00036	ENOG4108K3A	Glutathione S-transferase
H4CHR_00039	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
H4CHR_00040	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
H4CHR_00042	ENOG4107QJE	Chromosome Partitioning Protein
H4CHR_00044	ENOG4105FA0	parb-like partition protein
H4CHR_00046	ENOG4105CQB	FAD linked oxidase domain protein
H4CHR_00047	ENOG4108WBT	adenosyltransferase
H4CHR_00055	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
H4CHR_00056	ENOG4107QMS	site-determining protein
H4CHR_00057	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
H4CHR_00059	ENOG4105C2W	permease
H4CHR_00060	ENOG4105KA0	thioesterase Superfamily protein
H4CHR_00063	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
H4CHR_00064	ENOG4105JN3	extra-cytoplasmic solute receptor family protein
H4CHR_00069	ENOG4105F35	Catalyzes the NAD( )-dependent oxidation of L-carnitine to 3-dehydrocarnitine (By similarity)
H4CHR_00070	ENOG4105DE9	3-keto-5-aminohexanoate cleavage enzyme
H4CHR_00075	ENOG4105EVZ	LysR family transcriptional regulator
H4CHR_00077	ENOG4105F8J	Adenylate Guanylate cyclase
H4CHR_00080	ENOG4105CAF	HipA N-terminal domain protein
H4CHR_00081	ENOG4105C2W	permease
H4CHR_00082	ENOG4107SKI	cobyrinic Acid a,c-diamide synthase
H4CHR_00087	ENOG4108IV0	ABC, transporter
H4CHR_00088	ENOG4105C0Z	ABC transporter
H4CHR_00090	ENOG4105C32	Amino acid ABC transporter (Permease)
H4CHR_00092	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
H4CHR_00096	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
H4CHR_00101	ENOG4105DDW	LysR family Transcriptional regulator
H4CHR_00109	ENOG4105BZU	Histidine kinase
H4CHR_00110	ENOG4106T14	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
H4CHR_00112	ENOG4105DTD	Dehydrogenase
H4CHR_00116	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
H4CHR_00119	ENOG4108S10	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
H4CHR_00120	ENOG4105EBM	Alpha Beta Hydrolase Fold protein
H4CHR_00121	ENOG4105K89	arsenate reductase
H4CHR_00129	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
H4CHR_00130	ENOG4105F38	ABC transporter, permease
H4CHR_00131	ENOG4105NRK	Binding-protein-dependent transport systems, inner membrane component
H4CHR_00134	ENOG4107YYT	May reduce aminoacrylate peracid to aminoacrylate. Required to remove a toxic intermediate produce by the pyrimidine nitrogen degradation (By similarity)
H4CHR_00136	ENOG4107RUE	extracellular solute-binding protein family 1
H4CHR_00137	ENOG4107S9D	Alpha beta hydrolase
H4CHR_00139	ENOG4105CI2	imidazolone-5-propionate hydrolase
H4CHR_00145	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
H4CHR_00150	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
H4CHR_00151	ENOG4105K4H	Nlp p60 protein
H4CHR_00156	ENOG4105JSC	dimethylmenaquinone methyltransferase
H4CHR_00158	ENOG4107R6F	Alpha Beta Hydrolase Fold protein
H4CHR_00159	ENOG4105BZU	Histidine kinase
H4CHR_00161	ENOG4105DQE	DNA ligase
H4CHR_00163	ENOG4105FDF	Could be involved in DNA repair (By similarity)
H4CHR_00164	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
H4CHR_00170	ENOG4105VFU	Rna-binding protein
H4CHR_00176	ENOG4108I05	Binding-protein-dependent transport systems, inner membrane component
H4CHR_00178	ENOG4105E39	Enoyl-CoA hydratase
H4CHR_00180	ENOG4105D3Z	quinone oxidoreductase, yhdh yhfp family
H4CHR_00181	ENOG4108KSA	LysR family transcriptional regulator
H4CHR_00182	ENOG4105CEY	Amp-dependent synthetase and ligase
H4CHR_00184	ENOG4105DND	Transcriptional regulator
H4CHR_00189	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
H4CHR_00192	ENOG4105BZU	Histidine kinase
H4CHR_00193	ENOG4105BZU	Histidine kinase
H4CHR_00195	ENOG4105QD0	anti-sigma regulatory factor serine threonine protein kinase
H4CHR_00196	ENOG4105FUA	antagonist
H4CHR_00197	ENOG4107MMM	Anti-sigma-factor antagonist
H4CHR_00199	ENOG4105FAA	peptidase M23
H4CHR_00204	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
H4CHR_00208	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
H4CHR_00209	ENOG41086DT	Membrane protein of unknown function
H4CHR_00213	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
H4CHR_00214	ENOG4105D3R	alkyl hydroperoxide reductase
H4CHR_00215	ENOG4105ETT	transcriptional Regulator, LysR family
H4CHR_00216	ENOG4105C1G	acyl-Coa dehydrogenase
H4CHR_00217	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
H4CHR_00221	ENOG4105EMU	Dehydrogenase
H4CHR_00229	ENOG4105ETE	Transcriptional regulator (LacI family
H4CHR_00231	ENOG4105D9P	serine threonine protein kinase
H4CHR_00234	ENOG4105CSV	Glutaminase
H4CHR_00237	ENOG4107SYB	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
H4CHR_00243	ENOG4105DGI	Alkaline phosphatase
H4CHR_00248	ENOG4105C0M	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle (By similarity)
H4CHR_00250	ENOG4105C7B	Threonine dehydratase
H4CHR_00254	ENOG4105C9U	ATP-dependent DNA helicase RecQ
H4CHR_00258	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
H4CHR_00260	ENOG4105CZE	histidine utilization repressor
H4CHR_00261	ENOG4105C84	Histidine ammonia-lyase
H4CHR_00262	ENOG4105CGP	Urocanate hydratase
H4CHR_00267	ENOG4105CI2	imidazolone-5-propionate hydrolase
H4CHR_00272	ENOG4105C3R	Methionine synthase
H4CHR_00274	ENOG4105F52	Transcriptional regulator
H4CHR_00277	ENOG4105C3R	Methionine synthase
H4CHR_00278	ENOG41063ZV	
H4CHR_00279	ENOG41089I4	Inherit from COG: Glycosyl transferase, family 2
H4CHR_00284	ENOG4105CKT	filamentous hemagglutinin
H4CHR_00286	ENOG4108W9H	Tetr family transcriptional regulator
H4CHR_00287	ENOG4105DP0	ferredoxin-NADP reductase
H4CHR_00295	ENOG4105C0Z	ABC transporter
H4CHR_00296	ENOG4108IV0	ABC, transporter
H4CHR_00297	ENOG4108RWI	nicotinamidase
H4CHR_00298	ENOG4108XHQ	(2Fe-2S)-binding domain protein
H4CHR_00299	ENOG4105CE2	Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding
H4CHR_00305	ENOG4105C0P	Mg chelatase subunit ChlI
H4CHR_00307	ENOG4108YZA	Nitrogen regulatory protein pii
H4CHR_00308	ENOG4105BZU	Histidine kinase
H4CHR_00310	ENOG4105EU8	FAD linked oxidase domain protein
H4CHR_00311	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
H4CHR_00313	ENOG4108V06	Glutathione peroxidase
H4CHR_00315	ENOG4108J8Q	Catalyzes the facilitated diffusion of 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) into the cell (By similarity)
H4CHR_00316	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
H4CHR_00317	ENOG4105D2K	citrate carrier protein
H4CHR_00318	ENOG41084M5	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
H4CHR_00319	ENOG4105MP9	class II Aldolase
H4CHR_00321	ENOG4105C01	Dihydroxy-acid dehydratase
H4CHR_00325	ENOG4107THI	3,4-dihydroxyphenylacetate 2,3-dioxygenase
H4CHR_00326	ENOG4105C26	Dehydrogenase
H4CHR_00330	ENOG4108V8F	Transcriptional regulator, MarR family
H4CHR_00332	ENOG4105DAB	fumarate reductase succinate dehydrogenase flavoprotein domain protein
H4CHR_00333	ENOG4105CHR	reductase
H4CHR_00334	ENOG4105CHR	reductase
H4CHR_00335	ENOG4108IV0	ABC, transporter
H4CHR_00336	ENOG4105C0Z	ABC transporter
H4CHR_00337	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
H4CHR_00338	ENOG4105C32	Amino acid ABC transporter (Permease)
H4CHR_00340	ENOG4105CHR	reductase
H4CHR_00342	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
H4CHR_00343	ENOG4105C94	Transporter
H4CHR_00345	ENOG4105DH7	May be involved in recombination (By similarity)
H4CHR_00346	ENOG4105CM2	brancheD-chain amino acid aminotransferase
H4CHR_00350	ENOG4105E0F	Histidine kinase
H4CHR_00351	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
H4CHR_00359	ENOG4105EMU	Dehydrogenase
H4CHR_00361	ENOG41061H0	Monooxygenase
H4CHR_00362	ENOG4105F04	LysR family Transcriptional regulator
H4CHR_00363	ENOG4105CGK	Exodeoxyribonuclease III
H4CHR_00364	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
H4CHR_00366	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
H4CHR_00367	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
H4CHR_00368	ENOG41080G2	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
H4CHR_00372	ENOG4105CJN	penicillin-binding protein
H4CHR_00375	ENOG4105DHJ	ABC, transporter
H4CHR_00379	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
H4CHR_00380	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
H4CHR_00384	ENOG4105D7N	magnesium and cobalt transport protein CorA
H4CHR_00385	ENOG4105D52	delta-aminolevulinic acid dehydratase
H4CHR_00386	ENOG4108YXA	Membrane
H4CHR_00388	ENOG4105NZG	Ferredoxin
H4CHR_00389	ENOG4105DHZ	alpha beta
H4CHR_00390	ENOG4105DZ1	carboxypeptidase
H4CHR_00391	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
H4CHR_00392	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
H4CHR_00393	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
H4CHR_00394	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
H4CHR_00395	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
H4CHR_00398	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
H4CHR_00399	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
H4CHR_00400	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
H4CHR_00401	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
H4CHR_00402	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
H4CHR_00403	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
H4CHR_00404	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
H4CHR_00405	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
H4CHR_00406	ENOG41084PQ	50s ribosomal protein l29
H4CHR_00407	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
H4CHR_00411	ENOG4105T86	cytochrome C
H4CHR_00412	ENOG4105KJP	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
H4CHR_00415	ENOG41080Z8	PHOSPHOCARRIER protein
H4CHR_00416	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
H4CHR_00419	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
H4CHR_00420	ENOG41062D9	Histidine kinase
H4CHR_00421	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
H4CHR_00423	ENOG4105F4P	)-transporter
H4CHR_00424	ENOG4105CEY	Amp-dependent synthetase and ligase
H4CHR_00425	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
H4CHR_00426	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
H4CHR_00427	ENOG4105F0I	Aminotransferase
H4CHR_00429	ENOG4107RAZ	it plays a direct role in the translocation of protons across the membrane (By similarity)
H4CHR_00430	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
H4CHR_00431	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
H4CHR_00432	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
H4CHR_00433	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
H4CHR_00434	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
H4CHR_00435	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
H4CHR_00436	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
H4CHR_00439	ENOG4105CNN	ABC, transporter
H4CHR_00440	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
H4CHR_00441	ENOG4105CIB	oxidoreductase Domain protein
H4CHR_00449	ENOG4107T0X	DNA ligase
H4CHR_00450	ENOG4107T0X	DNA ligase
H4CHR_00451	ENOG4107QRT	dEAD DEAH box helicase
H4CHR_00462	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
H4CHR_00463	ENOG4105BZS	acriflavin resistance protein
H4CHR_00464	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
H4CHR_00465	ENOG4108IG5	Transcriptional regulator
H4CHR_00469	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
H4CHR_00470	ENOG4105CC0	LysR family Transcriptional regulator
H4CHR_00472	ENOG4105CSH	Transporter
H4CHR_00474	ENOG4108Z4U	Ferredoxin
H4CHR_00477	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
H4CHR_00478	ENOG4107UX3	phosphatidylethanolamine N-methyltransferase
H4CHR_00481	ENOG4105CYF	SMP-30 gluconolaconase LRE domain protein
H4CHR_00484	ENOG4105C26	Dehydrogenase
H4CHR_00485	ENOG4107R5U	Periplasmic binding protein LacI transcriptional regulator
H4CHR_00486	ENOG4105DFW	ABC transporter
H4CHR_00488	ENOG4108HWW	ABC transporter
H4CHR_00489	ENOG4105C2J	ABC transporter
H4CHR_00490	ENOG4107R9N	ABC transporter
H4CHR_00491	ENOG41062B0	ABC transporter, permease
H4CHR_00498	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
H4CHR_00519	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
H4CHR_00521	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
H4CHR_00522	ENOG41082RQ	UPF0102 protein
H4CHR_00523	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
H4CHR_00525	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
H4CHR_00526	ENOG4105CZX	twitching motility protein
H4CHR_00527	ENOG4105CZX	twitching motility protein
H4CHR_00528	ENOG4105DFA	alanine racemase domain protein
H4CHR_00529	ENOG4105EW9	transcriptional regulator AsnC family
H4CHR_00530	ENOG4105D82	Glutamate dehydrogenase
H4CHR_00535	ENOG4105CYW	agmatinase
H4CHR_00537	ENOG4105S7S	phosphonate abc transporter
H4CHR_00538	ENOG4105D5T	phosphonate abc transporter
H4CHR_00539	ENOG4105EHI	Phosphonate ABC transporter, periplasmic
H4CHR_00540	ENOG4105E46	N-alpha,N-alpha,N-alpha-trimethyl-L-histidine metabolic process
H4CHR_00542	ENOG4105D4F	Synthesizes selenophosphate from selenide and ATP (By similarity)
H4CHR_00549	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
H4CHR_00552	ENOG4105CEY	Amp-dependent synthetase and ligase
H4CHR_00553	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
H4CHR_00556	ENOG41067MG	lrgb family
H4CHR_00557	ENOG4105VAW	lrga family
H4CHR_00558	ENOG4105CQB	FAD linked oxidase domain protein
H4CHR_00560	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
H4CHR_00571	ENOG4105E2Q	3-(3-hydroxy-phenyl)propionate hydroxylase
H4CHR_00581	ENOG4105CH2	amidohydrolase
H4CHR_00587	ENOG4105MH5	phosphoesterase PA-phosphatase related protein
H4CHR_00594	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
H4CHR_00595	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
H4CHR_00596	ENOG4105CB5	ATP-dependent DNA helicase recG
H4CHR_00597	ENOG4105C5Q	Transcriptional regulator
H4CHR_00599	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
H4CHR_00600	ENOG4105II7	pyrroline-5-carboxylate reductase
H4CHR_00601	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
H4CHR_00602	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
H4CHR_00603	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
H4CHR_00604	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
H4CHR_00605	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
H4CHR_00606	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
H4CHR_00607	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
H4CHR_00608	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
H4CHR_00609	ENOG4105VPB	50S ribosomal protein L30
H4CHR_00610	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
H4CHR_00611	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
H4CHR_00613	ENOG41067V7	50S ribosomal protein L36
H4CHR_00614	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
H4CHR_00615	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
H4CHR_00616	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
H4CHR_00617	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
H4CHR_00618	ENOG4108ZT0	50S ribosomal protein l17
H4CHR_00622	ENOG4105C1G	acyl-Coa dehydrogenase
H4CHR_00623	ENOG4108UKI	Enoyl-CoA hydratase
H4CHR_00626	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
H4CHR_00629	ENOG4105EJC	lysr family transcriptional regulator
H4CHR_00630	ENOG4105F6U	Short-chain dehydrogenase reductase Sdr
H4CHR_00631	ENOG4105CPP	Dehydrogenase, E1 component
H4CHR_00632	ENOG4107RUY	(E1 component), alpha subunit
H4CHR_00639	ENOG4105BZU	Histidine kinase
H4CHR_00642	ENOG4107R7Y	intracellular protease Pfpi family
H4CHR_00643	ENOG4105DZS	Phenylacetate-CoA ligase
H4CHR_00644	ENOG4108IV0	ABC, transporter
H4CHR_00648	ENOG4105C0Z	ABC transporter
H4CHR_00649	ENOG4108IQE	Amp-dependent synthetase and ligase
H4CHR_00650	ENOG4105IJJ	transcriptional regulator, crp fnr family
H4CHR_00652	ENOG410904N	short-chain dehydrogenase reductase
H4CHR_00657	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
H4CHR_00658	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
H4CHR_00659	ENOG4108R80	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity)
H4CHR_00660	ENOG4105C08	Histidine kinase
H4CHR_00661	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
H4CHR_00662	ENOG4105FE9	pseudouridine synthase
H4CHR_00663	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
H4CHR_00664	ENOG4105DHQ	Histidine kinase
H4CHR_00674	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
H4CHR_00675	ENOG4106A3M	Cytochrome p-450
H4CHR_00676	ENOG4105E27	serine threonine protein kinase
H4CHR_00678	ENOG4108ZHJ	Organic hydroperoxide resistance protein
H4CHR_00679	ENOG4105K56	Transcriptional regulator
H4CHR_00681	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
H4CHR_00682	ENOG4108HH9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
H4CHR_00687	ENOG4105C32	Amino acid ABC transporter (Permease)
H4CHR_00689	ENOG4105C0Z	ABC transporter
H4CHR_00691	ENOG4108IV0	ABC, transporter
H4CHR_00698	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
H4CHR_00699	ENOG4105D7T	ABC transporter
H4CHR_00709	ENOG4107S78	Band 7 protein
H4CHR_00711	ENOG4105EQN	UPF0261 protein
H4CHR_00712	ENOG4105C0Z	ABC transporter
H4CHR_00717	ENOG4105CI2	imidazolone-5-propionate hydrolase
H4CHR_00718	ENOG4105CI2	imidazolone-5-propionate hydrolase
H4CHR_00719	ENOG4107J5P	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity)
H4CHR_00720	ENOG4105ERH	Fumarylacetoacetate hydrolase
H4CHR_00726	ENOG4108194	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
H4CHR_00727	ENOG4109066	lysm domain bon superfamily protein
H4CHR_00732	ENOG4105CH5	extracellular solute-binding protein, family 7
H4CHR_00734	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
H4CHR_00734	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
H4CHR_00737	ENOG4105DC8	reductase
H4CHR_00740	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
H4CHR_00741	ENOG4105FYV	Amp nucleosidase
H4CHR_00743	ENOG4108ZHR	arsR family transcriptional regulator
H4CHR_00747	ENOG4105HEI	LysR family (Transcriptional regulator
H4CHR_00748	ENOG4105CJ1	ABC, transporter
H4CHR_00751	ENOG4106BRA	Membrane
H4CHR_00753	ENOG4105CH2	amidohydrolase
H4CHR_00756	ENOG4108J2R	molybdopterin oxidoreductase
H4CHR_00764	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
H4CHR_00766	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
H4CHR_00769	ENOG4105K64	Glycosyl transferase, family 2
H4CHR_00772	ENOG4105C0K	Gdp-mannose 4,6-dehydratase
H4CHR_00777	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
H4CHR_00778	ENOG4105EXC	Acyl-transferase
H4CHR_00783	ENOG4105CAS	nag kinase
H4CHR_00785	ENOG4105CMR	udp-glucose 4-epimerase
H4CHR_00790	ENOG410829K	Lysine exporter protein (Lyse ygga)
H4CHR_00793	ENOG4105IPI	Membrane
H4CHR_00796	ENOG4108ZCF	integral membrane protein
H4CHR_00803	ENOG4105E7U	AraC family transcriptional regulator
H4CHR_00805	ENOG4105CYM	Glutathione S-transferase
H4CHR_00809	ENOG4105BZU	Histidine kinase
H4CHR_00810	ENOG4105DG4	malate L-lactate dehydrogenase
H4CHR_00811	ENOG4105CTX	dehydratase
H4CHR_00812	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
H4CHR_00814	ENOG4108ERU	trap dicarboxylate transporter subunit DctP
H4CHR_00815	ENOG4107YCY	Transcriptional regulator
H4CHR_00816	ENOG4105I7Z	Short-chain dehydrogenase reductase Sdr
H4CHR_00817	ENOG4106517	Short-chain dehydrogenase reductase Sdr
H4CHR_00818	ENOG4105ERH	Fumarylacetoacetate hydrolase
H4CHR_00819	ENOG4105C26	Dehydrogenase
H4CHR_00820	ENOG4105EXG	Transcriptional regulator
H4CHR_00821	ENOG4105FDP	GntR family transcriptional regulator
H4CHR_00822	ENOG4105CP9	extracellular ligand-binding receptor
H4CHR_00823	ENOG4105C32	Amino acid ABC transporter (Permease)
H4CHR_00824	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
H4CHR_00825	ENOG4105C0Z	ABC transporter
H4CHR_00826	ENOG4108IV0	ABC, transporter
H4CHR_00828	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
H4CHR_00829	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
H4CHR_00839	ENOG4105CSU	acyl-Coa dehydrogenase
H4CHR_00843	ENOG4105CHU	acetyl-coa acetyltransferase
H4CHR_00845	ENOG41060WC	Enoyl-CoA hydratase
H4CHR_00846	ENOG4105NAU	thioesterase Superfamily protein
H4CHR_00847	ENOG4108JJ7	ABC transporter
H4CHR_00848	ENOG4105C5I	Dehydrogenase
H4CHR_00850	ENOG4105C32	Amino acid ABC transporter (Permease)
H4CHR_00851	ENOG4105CNN	ABC, transporter
H4CHR_00852	ENOG4105C0Z	ABC transporter
H4CHR_00853	ENOG4108IV0	ABC, transporter
H4CHR_00855	ENOG4105RE0	Asp Glu hydantoin racemase
H4CHR_00858	ENOG4108UAU	isochorismatase
H4CHR_00860	ENOG4107YNJ	LysR family Transcriptional regulator
H4CHR_00861	ENOG4107RP9	extracellular solute-binding protein, family 3
H4CHR_00862	ENOG4105EAD	ABC transporter
H4CHR_00863	ENOG4105DRP	amino acid AbC transporter
H4CHR_00864	ENOG4105CDA	abc transporter atp-binding protein
H4CHR_00865	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
H4CHR_00866	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
H4CHR_00868	ENOG4105CEY	Amp-dependent synthetase and ligase
H4CHR_00869	ENOG4105C1G	acyl-Coa dehydrogenase
H4CHR_00870	ENOG4105CC9	acyl-Coa dehydrogenase
H4CHR_00871	ENOG4105CHU	acetyl-coa acetyltransferase
H4CHR_00872	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
H4CHR_00873	ENOG4105CBN	LysR family transcriptional regulator
H4CHR_00877	ENOG4105C8Q	Methyl-accepting chemotaxis
H4CHR_00878	ENOG4108JQ1	Dehydrogenase
H4CHR_00879	ENOG4108TY5	Exhibits lactonase activity. Acts in cells with perturbed membrane integrity and is possibly related to the membrane homeostasis
H4CHR_00880	ENOG4105GAK	amidohydrolase 2
H4CHR_00882	ENOG4105JN3	extra-cytoplasmic solute receptor family protein
H4CHR_00883	ENOG4108JQ1	Dehydrogenase
H4CHR_00884	ENOG4105JSC	dimethylmenaquinone methyltransferase
H4CHR_00888	ENOG4107RSM	transcriptional regulator
H4CHR_00891	ENOG4105EKE	dihydroorotase
H4CHR_00899	ENOG4107HP6	Transcriptional regulator
H4CHR_00900	ENOG4105D0M	Protease HtpX homolog
H4CHR_00901	ENOG4105DZ0	fad dependent oxidoreductase
H4CHR_00903	ENOG4105FE9	pseudouridine synthase
H4CHR_00906	ENOG4107R0V	Pyruvate dehydrogenase
H4CHR_00908	ENOG4105CPP	Dehydrogenase, E1 component
H4CHR_00909	ENOG4107QSN	dihydrolipoamide acetyltransferase
H4CHR_00911	ENOG4107QX8	SPFH domain, Band 7 family protein
H4CHR_00912	ENOG4105D7N	magnesium and cobalt transport protein CorA
H4CHR_00916	ENOG4105JN3	extra-cytoplasmic solute receptor family protein
H4CHR_00921	ENOG4105E1J	oxidoreductase
H4CHR_00923	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
H4CHR_00926	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
H4CHR_00927	ENOG4105DR4	Methyltransferase
H4CHR_00928	ENOG4105CKI	cobalamin synthesis protein
H4CHR_00931	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
H4CHR_00932	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
H4CHR_00933	ENOG4108V6E	Cell division protein mraZ
H4CHR_00934	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
H4CHR_00937	ENOG4105CJN	penicillin-binding protein
H4CHR_00938	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
H4CHR_00939	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
H4CHR_00940	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
H4CHR_00941	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
H4CHR_00942	ENOG4105CNI	cell division protein FtsW
H4CHR_00943	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
H4CHR_00944	ENOG4105DFU	Cell wall formation (By similarity)
H4CHR_00945	ENOG4105CPF	Cell wall formation (By similarity)
H4CHR_00946	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
H4CHR_00947	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
H4CHR_00948	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
H4CHR_00949	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
H4CHR_00951	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
H4CHR_00953	ENOG4105IQJ	Involved in biosynthesis of the thiamine precursor thiazole (By similarity)
H4CHR_00954	ENOG4105K6V	RNA polymerase
H4CHR_00958	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
H4CHR_00959	ENOG4105KNE	Phosphatidate cytidylyltransferase
H4CHR_00972	ENOG4105E2X	shikimate dehydrogenase
H4CHR_00974	ENOG4108IEC	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction (By similarity)
H4CHR_00975	ENOG4105IPS	esterase
H4CHR_00976	ENOG4105CNI	cell division protein FtsW
H4CHR_00977	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
H4CHR_00978	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
H4CHR_00980	ENOG4105DFU	Cell wall formation (By similarity)
H4CHR_00982	ENOG4107QXG	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
H4CHR_00983	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
H4CHR_00984	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
H4CHR_00985	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
H4CHR_00987	ENOG4107T4Z	adenosine kinase
H4CHR_00989	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
H4CHR_00990	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
H4CHR_00992	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
H4CHR_00993	ENOG4107TUY	Histidine kinase
H4CHR_00996	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
H4CHR_00997	ENOG4105C3A	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) (By similarity)
H4CHR_00998	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
H4CHR_01000	ENOG4107WP9	Histidine kinase
H4CHR_01001	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
H4CHR_01003	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
H4CHR_01004	ENOG4105BZS	acriflavin resistance protein
H4CHR_01013	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
H4CHR_01015	ENOG4105FGE	Short-chain dehydrogenase reductase Sdr
H4CHR_01017	ENOG4105E2B	Taurine dioxygenase
H4CHR_01020	ENOG4105M0Y	
H4CHR_01025	ENOG4105CHR	reductase
H4CHR_01026	ENOG4105CBN	LysR family transcriptional regulator
H4CHR_01027	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
H4CHR_01030	ENOG4105BZP	glycoside hydrolase 15-related
H4CHR_01031	ENOG4108K4C	ec 3.1.3.12
H4CHR_01032	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
H4CHR_01034	ENOG4108302	MgtC SapB transporter
H4CHR_01035	ENOG4105E4C	Lytic transglycosylase catalytic
H4CHR_01036	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
H4CHR_01037	ENOG4105ETT	transcriptional Regulator, LysR family
H4CHR_01040	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
H4CHR_01044	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
H4CHR_01048	ENOG4105DAB	fumarate reductase succinate dehydrogenase flavoprotein domain protein
H4CHR_01049	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
H4CHR_01051	ENOG4105C32	Amino acid ABC transporter (Permease)
H4CHR_01052	ENOG4105C0Z	ABC transporter
H4CHR_01053	ENOG4108IV0	ABC, transporter
H4CHR_01058	ENOG4108IPJ	Membrane
H4CHR_01059	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
H4CHR_01062	ENOG4105PDP	Short chain dehydrogenase
H4CHR_01064	ENOG4108Z9W	Outer membrane porin
H4CHR_01068	ENOG4107YAQ	Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway (By similarity)
H4CHR_01069	ENOG4105CPU	Monooxygenase
H4CHR_01072	ENOG4105JN3	extra-cytoplasmic solute receptor family protein
H4CHR_01074	ENOG4105CBX	hi0933 family
H4CHR_01076	ENOG4105E2X	shikimate dehydrogenase
H4CHR_01077	ENOG4105EBM	Alpha Beta Hydrolase Fold protein
H4CHR_01104	ENOG4108UAU	isochorismatase
H4CHR_01106	ENOG4105C32	Amino acid ABC transporter (Permease)
H4CHR_01108	ENOG4105C0Z	ABC transporter
H4CHR_01109	ENOG4108IV0	ABC, transporter
H4CHR_01117	ENOG4105CHU	acetyl-coa acetyltransferase
H4CHR_01120	ENOG4105CHR	reductase
H4CHR_01121	ENOG4105R1U	AraC Family Transcriptional Regulator
H4CHR_01124	ENOG4105Y49	secretion protein, HlyD family
H4CHR_01126	ENOG4105CR8	Transcriptional regulator
H4CHR_01127	ENOG4108UAU	isochorismatase
H4CHR_01129	ENOG4107YV9	domain protein
H4CHR_01138	ENOG4108M9J	MaoC like domain protein
H4CHR_01141	ENOG4107RAW	3-carboxy-cis-cis-muconate cycloisomerase
H4CHR_01142	ENOG4105CK2	sodium dicarboxylate symporter
H4CHR_01143	ENOG4105F04	LysR family Transcriptional regulator
H4CHR_01145	ENOG4105C7F	AcnD-accessory protein PrpF
H4CHR_01146	ENOG4108M0I	Transcriptional regulator
H4CHR_01148	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
H4CHR_01149	ENOG4108HR6	Dehydrogenase
H4CHR_01151	ENOG4105C7W	Xanthine dehydrogenase
H4CHR_01152	ENOG4105CKI	cobalamin synthesis protein
H4CHR_01156	ENOG4105C2W	permease
H4CHR_01157	ENOG4108JQ9	ABC transporter
H4CHR_01158	ENOG4105UIB	(ABC) transporter
H4CHR_01167	ENOG4105C0Z	ABC transporter
H4CHR_01168	ENOG4108IV0	ABC, transporter
H4CHR_01169	ENOG4105C32	Amino acid ABC transporter (Permease)
H4CHR_01171	ENOG4105CHR	reductase
H4CHR_01174	ENOG4108IV0	ABC, transporter
H4CHR_01175	ENOG4105C0Z	ABC transporter
H4CHR_01178	ENOG4105CAD	extracellular ligand-binding receptor
H4CHR_01180	ENOG4107Z7P	Ferredoxin
H4CHR_01184	ENOG4105HEI	LysR family (Transcriptional regulator
H4CHR_01185	ENOG4108RYK	Nad-dependent epimerase dehydratase
H4CHR_01191	ENOG4105HJ8	Catalyzes the oxidative cleavage of the L-tryptophan (L- Trp) pyrrole ring (By similarity)
H4CHR_01193	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
H4CHR_01195	ENOG4105CC0	LysR family Transcriptional regulator
H4CHR_01198	ENOG4105CS1	NAD(P)H quinone oxidoreductase
H4CHR_01202	ENOG4105EUF	amidase EC 3.5.1.4
H4CHR_01205	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
H4CHR_01207	ENOG4105CF7	AraC family transcriptional regulator
H4CHR_01208	ENOG4108MJI	response regulator
H4CHR_01212	ENOG4105JGF	anti-sigma regulatory factor serine threonine protein kinase
H4CHR_01219	ENOG4105DS1	cytochrome b561
H4CHR_01220	ENOG4105EQ0	Major Facilitator superfamily
H4CHR_01221	ENOG4105HEI	LysR family (Transcriptional regulator
H4CHR_01224	ENOG4107RTM	4-alpha-glucanotransferase (EC 2.4.1.25)
H4CHR_01225	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
H4CHR_01228	ENOG4105CG3	alpha amylase, catalytic region
H4CHR_01229	ENOG4107S9Q	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB (By similarity)
H4CHR_01230	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
H4CHR_01231	ENOG4105CN2	monooxygenase, FAD-binding
H4CHR_01238	ENOG4105BZ1	(ABC) transporter
H4CHR_01240	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
H4CHR_01241	ENOG4105CQ0	ABC transporter
H4CHR_01243	ENOG4105D7Q	type ii secretion system
H4CHR_01245	ENOG4107QHF	type ii secretion system protein e
H4CHR_01254	ENOG4108VAU	general secretion pathway protein G
H4CHR_01256	ENOG4105C7B	Threonine dehydratase
H4CHR_01258	ENOG4108UKZ	OsmC family
H4CHR_01259	ENOG4108S0N	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol (By similarity)
H4CHR_01260	ENOG4108Z9W	Outer membrane porin
H4CHR_01262	ENOG4105CH2	amidohydrolase
H4CHR_01263	ENOG4105DEF	Extracellular solute-binding protein, family 5
H4CHR_01264	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
H4CHR_01265	ENOG4105C3U	ABC transporter
H4CHR_01266	ENOG4108JQ7	(ABC) transporter
H4CHR_01267	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
H4CHR_01270	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
H4CHR_01271	ENOG4107QP8	phosphohexose isomerase
H4CHR_01273	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
H4CHR_01274	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
H4CHR_01278	ENOG4105CHB	tonB-dependent Receptor
H4CHR_01280	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
H4CHR_01282	ENOG4105D1S	lipid A biosynthesis
H4CHR_01284	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
H4CHR_01285	ENOG4106RE7	Cytochrome
H4CHR_01288	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
H4CHR_01289	ENOG4105DQ2	Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity)
H4CHR_01291	ENOG4105XQ6	frataxin-like protein
H4CHR_01292	ENOG4108JQC	penicillin-binding protein 1A
H4CHR_01297	ENOG4105E4G	Type IV pilus
H4CHR_01298	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
H4CHR_01300	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
H4CHR_01307	ENOG4105DHJ	ABC, transporter
H4CHR_01308	ENOG4105CY3	ABC transporter, permease
H4CHR_01309	ENOG4107PE3	Mammalian cell entry related domain protein
H4CHR_01313	ENOG4105DA5	(ABC) transporter
H4CHR_01314	ENOG4105E3A	(ABC) transporter
H4CHR_01315	ENOG4105VFK	BolA family
H4CHR_01316	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
H4CHR_01317	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
H4CHR_01320	ENOG4105CIH	Imidazole acetol-phosphate transaminase
H4CHR_01321	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
H4CHR_01323	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
H4CHR_01325	ENOG4105DSB	aldose 1-epimerase
H4CHR_01326	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
H4CHR_01327	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
H4CHR_01328	ENOG4105KPZ	phosphoribosyl-atp pyrophosphatase
H4CHR_01330	ENOG4107YU2	histidine triad (hIT) protein
H4CHR_01331	ENOG4105WKS	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
H4CHR_01332	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
H4CHR_01333	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
H4CHR_01334	ENOG4105C0H	protease
H4CHR_01335	ENOG4107QNR	UPF0135 protein
H4CHR_01336	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
H4CHR_01337	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
H4CHR_01338	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
H4CHR_01339	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
H4CHR_01340	ENOG4105EIX	cytochrome c1
H4CHR_01341	ENOG4107MKT	Stringent starvation protein a
H4CHR_01342	ENOG4105KB2	stringent starvation protein b
H4CHR_01345	ENOG4105D6J	arsenicaL-resistance protein
H4CHR_01346	ENOG4105CAU	Arsenical resistance protein, ArsH
H4CHR_01348	ENOG4105CH2	amidohydrolase
H4CHR_01349	ENOG4105EN6	Membrane
H4CHR_01355	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
H4CHR_01358	ENOG4105M6F	mutator MutT protein
H4CHR_01359	ENOG41067SF	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity)
H4CHR_01362	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
H4CHR_01366	ENOG4107QHF	type ii secretion system protein e
H4CHR_01368	ENOG4108KMV	Glycosyl transferase (Group 1
H4CHR_01372	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
H4CHR_01374	ENOG4105DZ1	carboxypeptidase
H4CHR_01375	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
H4CHR_01377	ENOG4106WTF	Glycosyl transferase, family 2
H4CHR_01378	ENOG4105CH7	arginosuccinase
H4CHR_01379	ENOG4108HRK	Histidine kinase
H4CHR_01380	ENOG4108NEV	two component transcriptional regulator, LytTR family
H4CHR_01381	ENOG4105DSF	transport protein
H4CHR_01383	ENOG4105CSH	Transporter
H4CHR_01390	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
H4CHR_01391	ENOG4105CPQ	Dehydrogenase
H4CHR_01393	ENOG4105C32	Amino acid ABC transporter (Permease)
H4CHR_01394	ENOG4105CNN	ABC, transporter
H4CHR_01395	ENOG4105C0Z	ABC transporter
H4CHR_01396	ENOG4108IV0	ABC, transporter
H4CHR_01400	ENOG4105CXK	mandelate racemase muconate lactonizing
H4CHR_01403	ENOG4105HSS	phospholipase C
H4CHR_01404	ENOG4105BZ4	penicillin-binding protein
H4CHR_01406	ENOG4105KA0	thioesterase Superfamily protein
H4CHR_01409	ENOG4105EAH	synthase
H4CHR_01410	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
H4CHR_01411	ENOG4105K46	50S ribosomal protein l27
H4CHR_01412	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
H4CHR_01413	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
H4CHR_01415	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
H4CHR_01416	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
H4CHR_01417	ENOG4105E4C	Lytic transglycosylase catalytic
H4CHR_01418	ENOG4105C37	(CBS) domain
H4CHR_01419	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
H4CHR_01422	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
H4CHR_01423	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
H4CHR_01424	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
H4CHR_01426	ENOG4105EGS	Mechanosensitive ion channel
H4CHR_01427	ENOG4107T6V	glycerophosphoryl diester phosphodiesterase
H4CHR_01428	ENOG4108IJ9	(ABC) transporter
H4CHR_01430	ENOG4105E4X	binding-protein-dependent transport systems inner membrane Component
H4CHR_01432	ENOG4108JQ1	Dehydrogenase
H4CHR_01436	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
H4CHR_01439	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
H4CHR_01440	ENOG4108IA2	Sodium pantothenate symporter
H4CHR_01443	ENOG4105C9M	aspartyl-trna synthetase
H4CHR_01444	ENOG4108TIT	dATP pyrophosphohydrolase
H4CHR_01446	ENOG4105EUJ	GTP cyclohydrolase i
H4CHR_01453	ENOG4106H29	UPF0391 membrane protein
H4CHR_01454	ENOG4105BZU	Histidine kinase
H4CHR_01455	ENOG4105WH1	Two component transcriptional regulator luxr family
H4CHR_01458	ENOG41066T0	asmA family
H4CHR_01459	ENOG4105D06	uba thif-type nad fad binding protein
H4CHR_01460	ENOG4105CN1	protease
H4CHR_01461	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
H4CHR_01462	ENOG4105WZW	rhodanese family
H4CHR_01463	ENOG4105VW4	glutaredoxin 3
H4CHR_01464	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
H4CHR_01465	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
H4CHR_01466	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
H4CHR_01467	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
H4CHR_01469	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
H4CHR_01470	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
H4CHR_01471	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
H4CHR_01472	ENOG4108IYU	L-aspartate oxidase
H4CHR_01476	ENOG4105CHH	sulfate transporter
H4CHR_01478	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
H4CHR_01479	ENOG4108YXG	UPF0502 protein
H4CHR_01481	ENOG4107R11	Transcriptional regulator
H4CHR_01487	ENOG4108IEG	Formate dehydrogenase Alpha subunit
H4CHR_01489	ENOG4105SA9	Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
H4CHR_01497	ENOG4105QAX	Iron-sulfur
H4CHR_01501	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
H4CHR_01503	ENOG4105CV6	ABC transporter, permease
H4CHR_01505	ENOG4105C28	cystathionine
H4CHR_01506	ENOG41069M3	Transcriptional regulator
H4CHR_01507	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
H4CHR_01508	ENOG4105CMT	Dihydroxyacetone kinase
H4CHR_01510	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
H4CHR_01511	ENOG4105XDZ	Tripartite ATP-independent periplasmic transporter
H4CHR_01512	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
H4CHR_01513	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
H4CHR_01514	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
H4CHR_01515	ENOG4105C32	Amino acid ABC transporter (Permease)
H4CHR_01516	ENOG4105C0Z	ABC transporter
H4CHR_01517	ENOG4105CP9	extracellular ligand-binding receptor
H4CHR_01518	ENOG4108IV0	ABC, transporter
H4CHR_01519	ENOG4105CQB	FAD linked oxidase domain protein
H4CHR_01522	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
H4CHR_01523	ENOG4108RAC	Rubrerythrin
H4CHR_01528	ENOG4105W5Q	DNA repair protein (RadC
H4CHR_01529	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
H4CHR_01530	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
H4CHR_01531	ENOG4105C7B	Threonine dehydratase
H4CHR_01533	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
H4CHR_01535	ENOG4105DFP	Integrase
H4CHR_01594	ENOG4105C1G	acyl-Coa dehydrogenase
H4CHR_01595	ENOG4108M9J	MaoC like domain protein
H4CHR_01596	ENOG4105C1G	acyl-Coa dehydrogenase
H4CHR_01597	ENOG4105KF3	Short-chain dehydrogenase reductase Sdr
H4CHR_01598	ENOG4105CYC	Transferase
H4CHR_01599	ENOG4105CHU	acetyl-coa acetyltransferase
H4CHR_01602	ENOG4105C32	Amino acid ABC transporter (Permease)
H4CHR_01604	ENOG4105C0Z	ABC transporter
H4CHR_01605	ENOG4108IV0	ABC, transporter
H4CHR_01606	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
H4CHR_01610	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
H4CHR_01612	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
H4CHR_01613	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
H4CHR_01614	ENOG4108IPT	Naphthoate synthase
H4CHR_01615	ENOG4108IV0	ABC, transporter
H4CHR_01618	ENOG4105C32	Amino acid ABC transporter (Permease)
H4CHR_01620	ENOG4105BZJ	Electron transfer flavoprotein
H4CHR_01621	ENOG4105C10	Electron transfer flavoprotein
H4CHR_01624	ENOG4105CHR	reductase
H4CHR_01625	ENOG4105CJW	magnesium transporter
H4CHR_01626	ENOG4105C7I	Dehydrogenase
H4CHR_01628	ENOG4105BZU	Histidine kinase
H4CHR_01630	ENOG4105C31	Tryptophanyl-tRNA synthetase
H4CHR_01631	ENOG4108Z4T	Peptidase M50
H4CHR_01632	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
H4CHR_01634	ENOG4105DB7	PHP domain protein
H4CHR_01635	ENOG4105CSR	polyphosphate kinase 2
H4CHR_01637	ENOG4107TSX	ABC branched chain amino acid family transporter periplasmic ligand binding protein
H4CHR_01638	ENOG4105C32	Amino acid ABC transporter (Permease)
H4CHR_01640	ENOG4105C2J	ABC transporter
H4CHR_01641	ENOG4108IV0	ABC, transporter
H4CHR_01644	ENOG41079KZ	Major Facilitator Superfamily
H4CHR_01645	ENOG4108M9X	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
H4CHR_01646	ENOG4108Z6B	deaminase
H4CHR_01653	ENOG4105EYW	Ion transport protein
H4CHR_01660	ENOG4105BZU	Histidine kinase
H4CHR_01661	ENOG4105E6M	Sulphatase-modifying factor protein
H4CHR_01662	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
H4CHR_01664	ENOG4107SCA	Formamidase (EC 3.5.1.49)
H4CHR_01669	ENOG4107UXM	Membrane
H4CHR_01672	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
H4CHR_01673	ENOG4105D7T	ABC transporter
H4CHR_01675	ENOG4105C6K	Malic enzyme
H4CHR_01677	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
H4CHR_01678	ENOG4106P55	Transcriptional regulator
H4CHR_01680	ENOG4105CYM	Glutathione S-transferase
H4CHR_01681	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
H4CHR_01683	ENOG4105DC8	reductase
H4CHR_01687	ENOG4105CJ2	(LipO)protein
H4CHR_01688	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
H4CHR_01690	ENOG4107E2E	PKHD-type hydroxylase
H4CHR_01697	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
H4CHR_01703	ENOG4108YYH	Nadph-dependent fmn reductase
H4CHR_01707	ENOG4105ETE	Transcriptional regulator (LacI family
H4CHR_01709	ENOG4105RE0	Asp Glu hydantoin racemase
H4CHR_01713	ENOG4108IQC	2,3-dihydroxybenzoate-AMP ligase
H4CHR_01716	ENOG4108IG5	Transcriptional regulator
H4CHR_01717	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
H4CHR_01718	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
H4CHR_01720	ENOG4108ERU	trap dicarboxylate transporter subunit DctP
H4CHR_01732	ENOG4105JN3	extra-cytoplasmic solute receptor family protein
H4CHR_01733	ENOG4105FDP	GntR family transcriptional regulator
H4CHR_01735	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
H4CHR_01736	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
H4CHR_01737	ENOG4105C7F	AcnD-accessory protein PrpF
H4CHR_01742	ENOG4105EAM	Na Pi-cotransporter
H4CHR_01745	ENOG4105ETT	transcriptional Regulator, LysR family
H4CHR_01750	ENOG4108JQ7	(ABC) transporter
H4CHR_01752	ENOG4108JQ7	(ABC) transporter
H4CHR_01754	ENOG4105C3U	ABC transporter
H4CHR_01759	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
H4CHR_01761	ENOG4106FTQ	Taurine ABC transporter, periplasmic
H4CHR_01763	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
H4CHR_01764	ENOG4105CYM	Glutathione S-transferase
H4CHR_01768	ENOG4105CZ6	Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine (By similarity)
H4CHR_01769	ENOG4108FUF	Transcriptional regulator, IclR family
H4CHR_01774	ENOG4105C1G	acyl-Coa dehydrogenase
H4CHR_01775	ENOG4105CD5	CoA-binding domain protein
H4CHR_01779	ENOG4105HEI	LysR family (Transcriptional regulator
H4CHR_01781	ENOG4105CEY	Amp-dependent synthetase and ligase
H4CHR_01782	ENOG4108EKI	Dehydrogenase
H4CHR_01784	ENOG4108FUF	Transcriptional regulator, IclR family
H4CHR_01799	ENOG4105WH1	Two component transcriptional regulator luxr family
H4CHR_01800	ENOG4105ENE	Histidine kinase
H4CHR_01804	ENOG4108FUF	Transcriptional regulator, IclR family
H4CHR_01807	ENOG4105DUM	transcriptional regulator, lysR family
H4CHR_01808	ENOG4105DB1	molybdopterin oxidoreductase
H4CHR_01809	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
H4CHR_01810	ENOG4108KDI	dmso reductase anchor subunit
H4CHR_01814	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
H4CHR_01819	ENOG4105C3M	thioredoxin reductase
H4CHR_01824	ENOG4105CDA	abc transporter atp-binding protein
H4CHR_01829	ENOG4107QVM	von Willebrand factor, type A
H4CHR_01836	ENOG4105K88	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
H4CHR_01837	ENOG4108ZC9	flagellar basal-body rod protein flgc
H4CHR_01838	ENOG4105W00	Flagellar hook capping protein
H4CHR_01839	ENOG4105BZE	flagellar hook protein, FlgE
H4CHR_01840	ENOG4108KPB	Flagellar basal-body rod protein FlgF
H4CHR_01841	ENOG4105CGA	flagellar basal-body rod protein FlgG
H4CHR_01842	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
H4CHR_01844	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
H4CHR_01845	ENOG4105C8Q	Methyl-accepting chemotaxis
H4CHR_01846	ENOG4108V3W	Chemotaxis protein, CheW
H4CHR_01847	ENOG4105C8Q	Methyl-accepting chemotaxis
H4CHR_01848	ENOG4105C8Q	Methyl-accepting chemotaxis
H4CHR_01849	ENOG4105C8Q	Methyl-accepting chemotaxis
H4CHR_01850	ENOG4105C8Q	Methyl-accepting chemotaxis
H4CHR_01851	ENOG4105E1Q	flagellar hook-associated protein
H4CHR_01852	ENOG4105DTJ	flagellar hook-associated protein
H4CHR_01856	ENOG4108SVW	integral membrane protein
H4CHR_01857	ENOG4106HB6	Alpha beta hydrolase
H4CHR_01865	ENOG4105E0F	Histidine kinase
H4CHR_01872	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
H4CHR_01874	ENOG4105VS8	Flagellar biosynthetic protein fliq
H4CHR_01875	ENOG4105CN7	Flagellar biosynthetic protein FliP
H4CHR_01877	ENOG4105DD5	Flagellar motor switch protein
H4CHR_01878	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
H4CHR_01879	ENOG4107ZI8	flagellar basal body-associated protein flil
H4CHR_01880	ENOG4105WF4	Flagellar hook-length control protein
H4CHR_01881	ENOG4105GSA	Flagellar export protein flij
H4CHR_01882	ENOG4108JIR	Flagellum-specific ATP synthase
H4CHR_01884	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
H4CHR_01885	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
H4CHR_01888	ENOG4105DTS	flagellar hook-associated
H4CHR_01889	ENOG4105MQ3	flagellar protein FliS
H4CHR_01892	ENOG4105D00	flagellar biosynthetic protein flhB
H4CHR_01894	ENOG4106CIA	Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region
H4CHR_01895	ENOG4107RD7	Flagellar Motor Protein, MotA
H4CHR_01896	ENOG4105ER2	Ompa motb domain protein
H4CHR_01897	ENOG4105CBS	Chea signal transduction histidine kinase
H4CHR_01898	ENOG4105D58	Diguanylate phosphodiesterase
H4CHR_01899	ENOG4105BZU	Histidine kinase
H4CHR_01902	ENOG4108VYJ	response regulator receiver protein
H4CHR_01903	ENOG4108KCC	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity)
H4CHR_01906	ENOG4105D00	flagellar biosynthetic protein flhB
H4CHR_01907	ENOG4105D7B	Flagellar biosynthesis protein flha
H4CHR_01908	ENOG4105FZW	flagellar biosynthesis regulator FlhF
H4CHR_01910	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
H4CHR_01913	ENOG4105TV9	FHA Domain-Containing protein
H4CHR_01915	ENOG4105BZU	Histidine kinase
H4CHR_01918	ENOG4106IJN	integrase catalytic domain-containing protein
H4CHR_01947	ENOG4105EMN	RNA polymerase sigma factor
H4CHR_01959	ENOG4105BZU	Histidine kinase
H4CHR_01960	ENOG4105C01	Dihydroxy-acid dehydratase
H4CHR_01965	ENOG4105DF3	Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta-cleavage pathway for the degradation of aromatic compounds (By similarity)
H4CHR_01966	ENOG4105DIV	Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD( ) and coenzyme A. Is the final enzyme in the meta- cleavage pathway for the degradation of aromatic compounds (By similarity)
H4CHR_01968	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
H4CHR_01973	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
H4CHR_01974	ENOG4105CD8	aminopeptidase N
H4CHR_01975	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
H4CHR_01977	ENOG4105CPC	Aldo Keto reductase
H4CHR_01978	ENOG4108Z66	YbaK ebsC protein
H4CHR_01979	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
H4CHR_01980	ENOG4105M4H	endoribonuclease L-psp
H4CHR_01982	ENOG4108VPT	UPF0234 protein
H4CHR_01983	ENOG4105D4A	Cell wall formation (By similarity)
H4CHR_01984	ENOG4105CDH	Citrulline--aspartate ligase
H4CHR_01985	ENOG4105NBK	UPF0345 protein
H4CHR_01987	ENOG4105KUZ	arsenate reductase
H4CHR_01988	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
H4CHR_01991	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
H4CHR_01992	ENOG4105C28	cystathionine
H4CHR_01993	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
H4CHR_01999	ENOG4105CEY	Amp-dependent synthetase and ligase
H4CHR_02000	ENOG4105CHU	acetyl-coa acetyltransferase
H4CHR_02003	ENOG4105E1F	short-chain dehydrogenase reductase
H4CHR_02004	ENOG4105CF7	AraC family transcriptional regulator
H4CHR_02007	ENOG4105ETT	transcriptional Regulator, LysR family
H4CHR_02008	ENOG410846T	CoA-transferase family III
H4CHR_02009	ENOG4105E39	Enoyl-CoA hydratase
H4CHR_02012	ENOG4105C1Y	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis (By similarity)
H4CHR_02013	ENOG4105EM7	Selenocysteine-specific translation elongation factor
H4CHR_02014	ENOG4105C3M	thioredoxin reductase
H4CHR_02019	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
H4CHR_02020	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
H4CHR_02021	ENOG4107EFR	Flavocytochrome c
H4CHR_02022	ENOG4105CHR	reductase
H4CHR_02025	ENOG4107EFR	Flavocytochrome c
H4CHR_02028	ENOG41083Z3	extracellular ligand-binding receptor
H4CHR_02031	ENOG4105C32	Amino acid ABC transporter (Permease)
H4CHR_02032	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
H4CHR_02033	ENOG4105C0Z	ABC transporter
H4CHR_02034	ENOG4108IV0	ABC, transporter
H4CHR_02037	ENOG4105HEI	LysR family (Transcriptional regulator
H4CHR_02038	ENOG4105C10	Electron transfer flavoprotein
H4CHR_02039	ENOG4105BZJ	Electron transfer flavoprotein
H4CHR_02040	ENOG4105C3M	thioredoxin reductase
H4CHR_02043	ENOG4105C7W	Xanthine dehydrogenase
H4CHR_02045	ENOG4105C7N	Xanthine uracil vitamin C permease
H4CHR_02046	ENOG4108JQ9	ABC transporter
H4CHR_02047	ENOG4105UIB	(ABC) transporter
H4CHR_02050	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
H4CHR_02052	ENOG4105BZU	Histidine kinase
H4CHR_02053	ENOG4107QHF	type ii secretion system protein e
H4CHR_02054	ENOG4105BZU	Histidine kinase
H4CHR_02057	ENOG4108TJN	glycosyl transferase group 1
H4CHR_02058	ENOG4107QUY	Guanine deaminase
H4CHR_02059	ENOG4105DHP	deoxycytidine triphosphate deaminase
H4CHR_02060	ENOG4105CGZ	zinc metallopeptidase
H4CHR_02061	ENOG4105C1J	atp-dependent rna helicase
H4CHR_02062	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
H4CHR_02063	ENOG4105EE5	Membrane protein terC
H4CHR_02067	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
H4CHR_02068	ENOG4105QG4	Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity)
H4CHR_02069	ENOG41060W2	glyoxylate carboligase
H4CHR_02070	ENOG4105CC0	LysR family Transcriptional regulator
H4CHR_02073	ENOG4105EQP	Catalyzes the pyrimidine ring opening between N-3 and C- 4 by an unusual flavin hydroperoxide-catalyzed mechanism to yield ureidoacrylate peracid. It cleaves pyrmidine rings directly by adding oxygen atoms, making a toxic ureidoacrylate peracid product which can be spontaneously reduced to ureidoacrylate (By similarity)
H4CHR_02074	ENOG4106XMA	In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity)
H4CHR_02075	ENOG4107YYT	May reduce aminoacrylate peracid to aminoacrylate. Required to remove a toxic intermediate produce by the pyrimidine nitrogen degradation (By similarity)
H4CHR_02076	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
H4CHR_02077	ENOG4108RDT	NADH dehydrogenase NAD(P)H nitroreductase)
H4CHR_02078	ENOG4108VQN	4-hydroxyphenylacetate 3-monooxygenase reductase
H4CHR_02079	ENOG4108R86	Transcriptional regulator
H4CHR_02081	ENOG4107RUE	extracellular solute-binding protein family 1
H4CHR_02082	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
H4CHR_02083	ENOG4105F38	ABC transporter, permease
H4CHR_02084	ENOG4105NRK	Binding-protein-dependent transport systems, inner membrane component
H4CHR_02086	ENOG4107YCY	Transcriptional regulator
H4CHR_02087	ENOG4105CK2	sodium dicarboxylate symporter
H4CHR_02089	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
H4CHR_02091	ENOG4105DQ4	alcohol dehydrogenase
H4CHR_02098	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
H4CHR_02100	ENOG4107YNJ	LysR family Transcriptional regulator
H4CHR_02103	ENOG4108Z40	Transcriptional regulator
H4CHR_02108	ENOG4108M9J	MaoC like domain protein
H4CHR_02109	ENOG4105C1G	acyl-Coa dehydrogenase
H4CHR_02115	ENOG4105JSC	dimethylmenaquinone methyltransferase
H4CHR_02117	ENOG41084M5	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
H4CHR_02118	ENOG4105CBZ	Short-chain dehydrogenase reductase Sdr
H4CHR_02123	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
H4CHR_02124	ENOG4105W8H	transhydrogenase (subunit alpha
H4CHR_02125	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
H4CHR_02126	ENOG4108R85	Short chain dehydrogenase
H4CHR_02128	ENOG4108JGH	Tetr family transcriptional regulator
H4CHR_02129	ENOG4105CHR	reductase
H4CHR_02133	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
H4CHR_02137	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
H4CHR_02138	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
H4CHR_02143	ENOG4105E39	Enoyl-CoA hydratase
H4CHR_02147	ENOG4105DZS	Phenylacetate-CoA ligase
H4CHR_02152	ENOG4105C0Z	ABC transporter
H4CHR_02153	ENOG4108IV0	ABC, transporter
H4CHR_02154	ENOG4105CQB	FAD linked oxidase domain protein
H4CHR_02155	ENOG4108YXU	transcriptional regulator AsnC family
H4CHR_02159	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
H4CHR_02163	ENOG4105DZG	Dehydrogenase
H4CHR_02168	ENOG4105JN3	extra-cytoplasmic solute receptor family protein
H4CHR_02172	ENOG4105CJ1	ABC, transporter
H4CHR_02173	ENOG4105EZY	Pyrroloquinoline quinone biosynthesis protein E
H4CHR_02175	ENOG41086XE	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ (By similarity)
H4CHR_02176	ENOG4105JIE	May be involved in the transport of PQQ or its precursor to the periplasm (By similarity)
H4CHR_02180	ENOG4105EAB	amino acid AbC transporter
H4CHR_02182	ENOG4105C26	Dehydrogenase
H4CHR_02183	ENOG4105CEY	Amp-dependent synthetase and ligase
H4CHR_02187	ENOG4107XCH	Cyclase family
H4CHR_02189	ENOG4105CEY	Amp-dependent synthetase and ligase
H4CHR_02199	ENOG4107RCM	Releases the N-terminal proline from various substrates (By similarity)
H4CHR_02200	ENOG4105EA8	2-Nitropropane dioxygenase
H4CHR_02202	ENOG4105HF0	Membrane
H4CHR_02205	ENOG4105JN3	extra-cytoplasmic solute receptor family protein
H4CHR_02207	ENOG4105EGI	Transcriptional regulator
H4CHR_02209	ENOG4108ERU	trap dicarboxylate transporter subunit DctP
H4CHR_02211	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
H4CHR_02212	ENOG4105CEY	Amp-dependent synthetase and ligase
H4CHR_02221	ENOG4105EQ2	LysR family Transcriptional regulator
H4CHR_02222	ENOG4107S5I	aldo keto reductase
H4CHR_02224	ENOG4105CQB	FAD linked oxidase domain protein
H4CHR_02225	ENOG4105CBG	Sulfatase
H4CHR_02226	ENOG4106NZI	LysR family Transcriptional regulator
H4CHR_02230	ENOG4105CMJ	mandelate racemase muconate lactonizing
H4CHR_02231	ENOG4107YNJ	LysR family Transcriptional regulator
H4CHR_02236	ENOG4105KF3	Short-chain dehydrogenase reductase Sdr
H4CHR_02237	ENOG4105CC9	acyl-Coa dehydrogenase
H4CHR_02238	ENOG4105C1G	acyl-Coa dehydrogenase
H4CHR_02240	ENOG4105CEY	Amp-dependent synthetase and ligase
H4CHR_02243	ENOG4105RQF	LysR family Transcriptional regulator
H4CHR_02247	ENOG4105C5I	Dehydrogenase
H4CHR_02252	ENOG4105ETT	transcriptional Regulator, LysR family
H4CHR_02253	ENOG4105KME	endoribonuclease L-psp
H4CHR_02259	ENOG4105F38	ABC transporter, permease
H4CHR_02266	ENOG4105CQZ	Histidine kinase
H4CHR_02275	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
H4CHR_02277	ENOG4105C08	Histidine kinase
H4CHR_02278	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
H4CHR_02284	ENOG4105C7W	Xanthine dehydrogenase
H4CHR_02285	ENOG4105DIP	Molybdopterin dehydrogenase FAD-binding
H4CHR_02286	ENOG4107XKX	isoquinoline 1-oxidoreductase, alpha subunit
H4CHR_02287	ENOG4105ECQ	AraC Family Transcriptional Regulator
H4CHR_02288	ENOG4108SUT	Major Facilitator Superfamily
H4CHR_02289	ENOG4105MDH	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
H4CHR_02290	ENOG4105CV8	reductase
H4CHR_02291	ENOG4105C2W	permease
H4CHR_02297	ENOG4105CTC	Lipopolysaccharide biosynthesis protein-like protein
H4CHR_02298	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
H4CHR_02301	ENOG4107YCY	Transcriptional regulator
H4CHR_02307	ENOG410810E	transcriptional regulator, lysR family
H4CHR_02308	ENOG4105CI0	Citrate lyase
H4CHR_02310	ENOG4105GAK	amidohydrolase 2
H4CHR_02312	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
H4CHR_02315	ENOG4105CJ1	ABC, transporter
H4CHR_02316	ENOG4107QWP	ABC-2 type transporter
H4CHR_02317	ENOG4107QWP	ABC-2 type transporter
H4CHR_02323	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
H4CHR_02328	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
H4CHR_02329	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
H4CHR_02330	ENOG4109025	Glyoxalase Bleomycin resistance protein (Dioxygenase
H4CHR_02333	ENOG4105R0I	Feruloyl esterase
H4CHR_02352	ENOG4105CDV	Ompa motb domain protein
H4CHR_02362	ENOG4105EMN	RNA polymerase sigma factor
H4CHR_02363	ENOG4108K2P	TRANSCRIPTIONal
H4CHR_02367	ENOG4108UKI	Enoyl-CoA hydratase
H4CHR_02369	ENOG4105D5K	Hemolysin activator protein
H4CHR_02370	ENOG4105CKT	filamentous hemagglutinin
H4CHR_02375	ENOG4105C59	p-type ATPase
H4CHR_02377	ENOG4105CE2	Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding
H4CHR_02380	ENOG4107RT3	EamA-like transporter family
H4CHR_02381	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
H4CHR_02383	ENOG4107QKV	phosphomannomutase
H4CHR_02384	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
H4CHR_02389	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
H4CHR_02393	ENOG4105YA8	Transcriptional regulator
H4CHR_02394	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
H4CHR_02397	ENOG4105CFH	Aspartokinase
H4CHR_02398	ENOG4105CPC	Aldo Keto reductase
H4CHR_02400	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
H4CHR_02405	ENOG4105C01	Dihydroxy-acid dehydratase
H4CHR_02406	ENOG4108UHU	Aldolase
H4CHR_02408	ENOG4108UYE	Lactoylglutathione lyase
H4CHR_02411	ENOG4107RCV	ABC transporter, permease
H4CHR_02413	ENOG4105CEY	Amp-dependent synthetase and ligase
H4CHR_02414	ENOG4105EA8	2-Nitropropane dioxygenase
H4CHR_02417	ENOG4105JN3	extra-cytoplasmic solute receptor family protein
H4CHR_02418	ENOG4105JN3	extra-cytoplasmic solute receptor family protein
H4CHR_02425	ENOG4105EMU	Dehydrogenase
H4CHR_02427	ENOG4108RTU	Aldolase
H4CHR_02429	ENOG4105C01	Dihydroxy-acid dehydratase
H4CHR_02430	ENOG4107EJG	GntR family transcriptional regulator
H4CHR_02432	ENOG4105D56	permease protein
H4CHR_02437	ENOG4105C1J	atp-dependent rna helicase
H4CHR_02439	ENOG4105C5H	ABC transporter
H4CHR_02442	ENOG4105KXX	peptidase s58 dmpa
H4CHR_02445	ENOG4107VXM	glycerophosphoryl diester phosphodiesterase
H4CHR_02448	ENOG4105E5Q	amino acid AbC transporter
H4CHR_02449	ENOG4105DRP	amino acid AbC transporter
H4CHR_02450	ENOG4107RP9	extracellular solute-binding protein, family 3
H4CHR_02452	ENOG4108Z9K	Osmotically inducible protein
H4CHR_02453	ENOG4105CEY	Amp-dependent synthetase and ligase
H4CHR_02455	ENOG4108R6G	acetyltransferase
H4CHR_02456	ENOG4109025	Glyoxalase Bleomycin resistance protein (Dioxygenase
H4CHR_02457	ENOG4105CEP	NADH dehydrogenase
H4CHR_02459	ENOG41067HS	methyltransferase
H4CHR_02462	ENOG41081QV	Universal stress protein
H4CHR_02463	ENOG4105D3G	Pseudouridine synthase
H4CHR_02468	ENOG4105CKW	Inner membrane protein yedI
H4CHR_02469	ENOG4105CR7	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA (By similarity)
H4CHR_02472	ENOG4105F4K	antigen 43
H4CHR_02475	ENOG4106CJB	Phospholipase Carboxylesterase
H4CHR_02476	ENOG4105D9M	gamma-glutamylcysteine synthetase
H4CHR_02477	ENOG4107QWB	Ornithine cyclodeaminase
H4CHR_02478	ENOG4108UYB	regulatoR
H4CHR_02480	ENOG4105DY9	regulatoR
H4CHR_02481	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
H4CHR_02486	ENOG4105E2B	Taurine dioxygenase
H4CHR_02487	ENOG4107RQ0	Maleylacetate reductase
H4CHR_02489	ENOG4105GZI	Transcriptional regulator
H4CHR_02490	ENOG4105CEY	Amp-dependent synthetase and ligase
H4CHR_02491	ENOG4105DE9	3-keto-5-aminohexanoate cleavage enzyme
H4CHR_02492	ENOG4105ERH	Fumarylacetoacetate hydrolase
H4CHR_02493	ENOG4105EA8	2-Nitropropane dioxygenase
H4CHR_02499	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
H4CHR_02500	ENOG4105V9V	Short-chain dehydrogenase reductase Sdr
H4CHR_02501	ENOG4107XZC	Restriction modification system DNA (Specificity
H4CHR_02504	ENOG4105CX6	glutaminyL-tRNA synthetase
H4CHR_02506	ENOG4108VAC	response regulator
H4CHR_02507	ENOG4108HRK	Histidine kinase
H4CHR_02511	ENOG4105BZS	acriflavin resistance protein
H4CHR_02512	ENOG4105BZS	acriflavin resistance protein
H4CHR_02513	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
H4CHR_02515	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
H4CHR_02520	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
H4CHR_02522	ENOG4105ENH	Sulfatase
H4CHR_02523	ENOG4105JN3	extra-cytoplasmic solute receptor family protein
H4CHR_02529	ENOG4105ECY	inositol monophosphatase
H4CHR_02531	ENOG4105D7W	serine acetyltransferase
H4CHR_02532	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
H4CHR_02534	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
H4CHR_02536	ENOG4105VCC	30S ribosomal protein S21
H4CHR_02537	ENOG4105CBX	hi0933 family
H4CHR_02539	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
H4CHR_02540	ENOG4108MTB	glycosyl transferase family
H4CHR_02543	ENOG4108IFG	nitrite reductase, (NAD(P)H)
H4CHR_02544	ENOG4105D9P	serine threonine protein kinase
H4CHR_02547	ENOG4105D7T	ABC transporter
H4CHR_02549	ENOG4105I5W	Transporter
H4CHR_02551	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
H4CHR_02553	ENOG4107Y70	Heat shock protein
H4CHR_02554	ENOG4105ES9	amino acid
H4CHR_02556	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
H4CHR_02557	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
H4CHR_02559	ENOG4105CP7	Triose-phosphate isomerase
H4CHR_02560	ENOG4107EJC	Preprotein translocase subunit SecG
H4CHR_02562	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
H4CHR_02563	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
H4CHR_02564	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
H4CHR_02565	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
H4CHR_02567	ENOG4107QIZ	NADH dehydrogenase
H4CHR_02568	ENOG4108IEH	NADH dehydrogenase subunit g
H4CHR_02569	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
H4CHR_02570	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
H4CHR_02571	ENOG4105DF2	NADH dehydrogenase subunit j
H4CHR_02572	ENOG4105M5H	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
H4CHR_02574	ENOG4105C8S	subunit m
H4CHR_02575	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
H4CHR_02577	ENOG4108YZ4	nudix hydrolase
H4CHR_02579	ENOG4105BZ1	(ABC) transporter
H4CHR_02580	ENOG4108T3F	Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes
H4CHR_02582	ENOG4105CW7	secretion protein, HlyD family
H4CHR_02583	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
H4CHR_02584	ENOG4105C0Z	ABC transporter
H4CHR_02585	ENOG4108IV0	ABC, transporter
H4CHR_02588	ENOG4105C32	Amino acid ABC transporter (Permease)
H4CHR_02592	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
H4CHR_02594	ENOG4105CSH	Transporter
H4CHR_02596	ENOG4108SHN	Glycosyl transferase, family 2
H4CHR_02602	ENOG4105GRZ	Ycii-related protein
H4CHR_02603	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
H4CHR_02606	ENOG4105JXH	GntR family transcriptional regulator
H4CHR_02609	ENOG410846T	CoA-transferase family III
H4CHR_02610	ENOG4105EXG	Transcriptional regulator
H4CHR_02613	ENOG4105CG3	alpha amylase, catalytic region
H4CHR_02614	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
H4CHR_02617	ENOG4105CQ0	ABC transporter
H4CHR_02619	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
H4CHR_02620	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
H4CHR_02622	ENOG4105DT1	RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate
H4CHR_02624	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
H4CHR_02625	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
H4CHR_02626	ENOG4105ETE	Transcriptional regulator (LacI family
H4CHR_02628	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
H4CHR_02629	ENOG4105DQR	SNARE associated Golgi
H4CHR_02632	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
H4CHR_02633	ENOG4105K8N	protein family UPF0079, ATPase
H4CHR_02634	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
H4CHR_02638	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
H4CHR_02641	ENOG4105ED9	Protein of unknown function (DUF455)
H4CHR_02642	ENOG4108Z0R	Transferase
H4CHR_02643	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
H4CHR_02645	ENOG4105F73	Catalyzes the deformylation of 4-deoxy-4-formamido-L- arabinose-phosphoundecaprenol to 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
H4CHR_02647	ENOG4108I2E	Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto- arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4- amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido- arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
H4CHR_02648	ENOG4105CKK	Glycosyl transferase, family 2
H4CHR_02649	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
H4CHR_02650	ENOG41060GT	Translocates 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane (By similarity)
H4CHR_02651	ENOG4105SA9	Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
H4CHR_02652	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
H4CHR_02653	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
H4CHR_02654	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
H4CHR_02655	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
H4CHR_02656	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
H4CHR_02658	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
H4CHR_02660	ENOG4108YZY	peptidylprolyl cis-trans isomerase
H4CHR_02661	ENOG4105EZE	Cupin 4 family protein
H4CHR_02664	ENOG4105Q2H	domain protein
H4CHR_02665	ENOG4105GJM	(LipO)protein
H4CHR_02666	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
H4CHR_02670	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
H4CHR_02672	ENOG4105EMN	RNA polymerase sigma factor
H4CHR_02673	ENOG4105E4C	Lytic transglycosylase catalytic
H4CHR_02674	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
H4CHR_02679	ENOG4105DRP	amino acid AbC transporter
H4CHR_02680	ENOG4105E5Q	amino acid AbC transporter
H4CHR_02681	ENOG4105EAB	amino acid AbC transporter
H4CHR_02682	ENOG4105CDA	abc transporter atp-binding protein
H4CHR_02684	ENOG4105D7K	pfkb domain protein
H4CHR_02686	ENOG4108M60	Transcriptional regulator
H4CHR_02688	ENOG4105C26	Dehydrogenase
H4CHR_02689	ENOG4107RTG	Major Facilitator superfamily
H4CHR_02690	ENOG4108UYU	AsnC family transcriptional regulator
H4CHR_02695	ENOG4108EC8	DNA internalization-related competence protein ComEC
H4CHR_02698	ENOG4108JJA	ABC, transporter
H4CHR_02699	ENOG4105C42	Type I secretion membrane fusion protein (HlyD
H4CHR_02706	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
H4CHR_02707	ENOG4105E98	transcriptional regulator DeoR family
H4CHR_02708	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
H4CHR_02709	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
H4CHR_02710	ENOG4108IJ9	(ABC) transporter
H4CHR_02713	ENOG4105EB1	binding-protein-dependent transport systems inner membrane Component
H4CHR_02717	ENOG4105CVE	Lytic murein transglycosylase
H4CHR_02718	ENOG4105F8C	transglutaminase domain-containing protein
H4CHR_02720	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
H4CHR_02721	ENOG4105DGU	Histone deacetylase
H4CHR_02722	ENOG4105EGS	Mechanosensitive ion channel
H4CHR_02723	ENOG4105BZJ	Electron transfer flavoprotein
H4CHR_02724	ENOG4105C10	Electron transfer flavoprotein
H4CHR_02725	ENOG4105CSU	acyl-Coa dehydrogenase
H4CHR_02731	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
H4CHR_02732	ENOG4105C4M	(Ubiquinol oxidase) subunit I
H4CHR_02738	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
H4CHR_02741	ENOG4105VN1	Heat shock protein
H4CHR_02742	ENOG4105CSH	Transporter
H4CHR_02745	ENOG4105IQ5	FAD linked oxidase domain protein
H4CHR_02747	ENOG4107HP6	Transcriptional regulator
H4CHR_02748	ENOG4105E2X	shikimate dehydrogenase
H4CHR_02750	ENOG4105E2X	shikimate dehydrogenase
H4CHR_02751	ENOG4107RAW	3-carboxy-cis-cis-muconate cycloisomerase
H4CHR_02758	ENOG4105EGI	Transcriptional regulator
H4CHR_02759	ENOG4105CBP	Major Facilitator
H4CHR_02762	ENOG4105CHP	RNA polymerase
H4CHR_02764	ENOG4107Z4K	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
H4CHR_02766	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
H4CHR_02767	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
H4CHR_02768	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
H4CHR_02771	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
H4CHR_02773	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
H4CHR_02774	ENOG4105EXW	epimerase dehydratase
H4CHR_02775	ENOG4105BZU	Histidine kinase
H4CHR_02776	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
H4CHR_02777	ENOG4105CHR	reductase
H4CHR_02780	ENOG4105DHQ	Histidine kinase
H4CHR_02781	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
H4CHR_02783	ENOG4105DIJ	Phosphoethanolamine transferase
H4CHR_02786	ENOG4107FQ9	ethanolamine ammonia-lyase
H4CHR_02787	ENOG4105CPD	ethanolamine ammonia-lyase
H4CHR_02788	ENOG4108V1T	peptidylprolyl cis-trans isomerase
H4CHR_02790	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
H4CHR_02792	ENOG4105CF1	Alkylated DNA repair protein
H4CHR_02798	ENOG4108KX4	response regulator
H4CHR_02805	ENOG4105C26	Dehydrogenase
H4CHR_02807	ENOG4105E39	Enoyl-CoA hydratase
H4CHR_02808	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
H4CHR_02810	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
H4CHR_02817	ENOG4106S2D	Transcriptional regulator
H4CHR_02818	ENOG4105WH1	Two component transcriptional regulator luxr family
H4CHR_02821	ENOG4107RZC	phospholipase d
H4CHR_02822	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
H4CHR_02823	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
H4CHR_02825	ENOG4105BZ1	(ABC) transporter
H4CHR_02826	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
H4CHR_02831	ENOG4105C0B	DNA polymerase III (alpha subunit)
H4CHR_02835	ENOG4108W9H	Tetr family transcriptional regulator
H4CHR_02839	ENOG4105BZ9	Cytochrome C oxidase, subunit I
H4CHR_02840	ENOG4105CV4	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
H4CHR_02843	ENOG4105NXH	GreA GreB family elongation factor
H4CHR_02846	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
H4CHR_02847	ENOG4108ERU	trap dicarboxylate transporter subunit DctP
H4CHR_02850	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
H4CHR_02851	ENOG4105KF3	Short-chain dehydrogenase reductase Sdr
H4CHR_02853	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
H4CHR_02854	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
H4CHR_02855	ENOG4105E39	Enoyl-CoA hydratase
H4CHR_02858	ENOG4105C1G	acyl-Coa dehydrogenase
H4CHR_02859	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
H4CHR_02860	ENOG4105C1G	acyl-Coa dehydrogenase
H4CHR_02869	ENOG4105CHR	reductase
H4CHR_02871	ENOG4108U78	Glutathione S-transferase
H4CHR_02883	ENOG4105EYH	Exonuclease
H4CHR_02891	ENOG4105C2M	dna polymerase I
H4CHR_03008	ENOG4105D82	Glutamate dehydrogenase
H4CHR_03010	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
H4CHR_03012	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
H4CHR_03018	ENOG4108MUZ	hydrolase
H4CHR_03019	ENOG4107HP6	Transcriptional regulator
H4CHR_03020	ENOG4105CHR	reductase
H4CHR_03021	ENOG4105C7K	acetolactate synthase
H4CHR_03022	ENOG4108Q27	Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate (By similarity)
H4CHR_03026	ENOG4105MSY	salicylate hydroxylase
H4CHR_03030	ENOG4108Z9W	Outer membrane porin
H4CHR_03032	ENOG4106NZI	LysR family Transcriptional regulator
H4CHR_03033	ENOG4105E2B	Taurine dioxygenase
H4CHR_03035	ENOG4105C26	Dehydrogenase
H4CHR_03038	ENOG4105MP9	class II Aldolase
H4CHR_03042	ENOG4105C59	p-type ATPase
H4CHR_03043	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
H4CHR_03051	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
H4CHR_03055	ENOG4105F8V	Hydrolase, tatD family
H4CHR_03057	ENOG4107QRG	dna polymerase iii
H4CHR_03058	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
H4CHR_03059	ENOG4105HHA	aminodeoxychorismate lyase
H4CHR_03060	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
H4CHR_03061	ENOG4105VCD	cytoplasmic protein
H4CHR_03062	ENOG4105D22	carbon starvation protein
H4CHR_03069	ENOG4105ETT	transcriptional Regulator, LysR family
H4CHR_03073	ENOG4105BZM	domain protein
H4CHR_03074	ENOG4105EJC	lysr family transcriptional regulator
H4CHR_03079	ENOG4107QJQ	Mate efflux family protein
H4CHR_03088	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
H4CHR_03089	ENOG4105C2C	drug resistance transporter, Bcr CflA
H4CHR_03092	ENOG4105DY2	Paraquat-inducible protein b
H4CHR_03093	ENOG4105F1S	paraquat-inducible protein a
H4CHR_03094	ENOG4105F1S	paraquat-inducible protein a
H4CHR_03095	ENOG4105HEI	LysR family (Transcriptional regulator
H4CHR_03096	ENOG4105F27	Major Facilitator
H4CHR_03097	ENOG4105CPC	Aldo Keto reductase
H4CHR_03098	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
H4CHR_03099	ENOG4105DHQ	Histidine kinase
H4CHR_03101	ENOG4107U5X	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
H4CHR_03102	ENOG4105ETT	transcriptional Regulator, LysR family
H4CHR_03103	ENOG4105KCV	RNA signal recognition particle 4.5S RNA
H4CHR_03107	ENOG4105CSU	acyl-Coa dehydrogenase
H4CHR_03108	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
H4CHR_03110	ENOG4105CHR	reductase
H4CHR_03112	ENOG4105CSU	acyl-Coa dehydrogenase
H4CHR_03113	ENOG4105CHU	acetyl-coa acetyltransferase
H4CHR_03114	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
H4CHR_03115	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
H4CHR_03116	ENOG4108IV0	ABC, transporter
H4CHR_03117	ENOG4105C0Z	ABC transporter
H4CHR_03119	ENOG4105C32	Amino acid ABC transporter (Permease)
H4CHR_03121	ENOG4105CEY	Amp-dependent synthetase and ligase
H4CHR_03122	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
H4CHR_03123	ENOG4105CNG	UPF0061 protein
H4CHR_03124	ENOG4105E0X	reductase
H4CHR_03125	ENOG4107835	probably involved in intracellular septation (By similarity)
H4CHR_03127	ENOG4107TF3	peptidylprolyl cis-trans isomerase
H4CHR_03128	ENOG4108ETH	Formylglycinamide ribotide synthetase
H4CHR_03129	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
H4CHR_03130	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
H4CHR_03131	ENOG4105MGM	doxx family
H4CHR_03132	ENOG4108RBJ	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
H4CHR_03134	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
H4CHR_03136	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
H4CHR_03143	ENOG410635M	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
H4CHR_03144	ENOG4108IJ6	ABC transporter
H4CHR_03145	ENOG4105ECW	sulfate abc transporter
H4CHR_03146	ENOG4108I5D	sulfate abc transporter
H4CHR_03147	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
H4CHR_03149	ENOG4105JQN	Transcriptional regulator
H4CHR_03150	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
H4CHR_03152	ENOG4105D7W	serine acetyltransferase
H4CHR_03153	ENOG4106NZI	LysR family Transcriptional regulator
H4CHR_03156	ENOG4105DG4	malate L-lactate dehydrogenase
H4CHR_03158	ENOG4108UZX	fmn reductase
H4CHR_03159	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
H4CHR_03160	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
H4CHR_03161	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
H4CHR_03163	ENOG4108UT2	hemolysin iii
H4CHR_03165	ENOG4107QNK	)-transporter
H4CHR_03168	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
H4CHR_03170	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
H4CHR_03171	ENOG4108Z4U	Ferredoxin
H4CHR_03172	ENOG4105CAY	ferredoxin--nadp reductase
H4CHR_03173	ENOG4105D1E	Undecaprenyl pyrophosphate phosphatase
H4CHR_03175	ENOG4105W2Z	cytochrome C, class I
H4CHR_03177	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
H4CHR_03178	ENOG4108TEB	UPF0114 protein
H4CHR_03188	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
H4CHR_03189	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
H4CHR_03190	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
H4CHR_03191	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
H4CHR_03194	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
H4CHR_03199	ENOG4105DFC	had-superfamily hydrolase, subfamily ia, variant
H4CHR_03200	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
H4CHR_03205	ENOG4108IV0	ABC, transporter
H4CHR_03208	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
H4CHR_03216	ENOG4105CHR	reductase
H4CHR_03220	ENOG4105CC0	LysR family Transcriptional regulator
H4CHR_03222	ENOG4105E39	Enoyl-CoA hydratase
H4CHR_03224	ENOG4105CC9	acyl-Coa dehydrogenase
H4CHR_03226	ENOG4105CHR	reductase
H4CHR_03230	ENOG4107SFQ	iron-sulfur binding
H4CHR_03238	ENOG4105CV4	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
H4CHR_03242	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
H4CHR_03248	ENOG4105DHQ	Histidine kinase
H4CHR_03249	ENOG4105VEJ	Heat shock protein
H4CHR_03250	ENOG4105CSR	polyphosphate kinase 2
H4CHR_03252	ENOG41069M3	Transcriptional regulator
H4CHR_03257	ENOG4105CFH	Aspartokinase
H4CHR_03258	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
H4CHR_03259	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
H4CHR_03261	ENOG4105C8N	cysteinyl-tRNA synthetase
H4CHR_03266	ENOG4105EXZ	Involved in the regulation of ptsG expression by binding and inactivating Mlc (By similarity)
H4CHR_03269	ENOG4106S48	Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division
H4CHR_03270	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
H4CHR_03271	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
H4CHR_03273	ENOG4105CWU	Biogenesis protein
H4CHR_03283	ENOG4106855	Competence protein
H4CHR_03284	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
H4CHR_03285	ENOG4108R6K	riboflavin synthase, subunit alpha
H4CHR_03286	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
H4CHR_03287	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
H4CHR_03288	ENOG4107YIM	Involved in the transcription termination process (By similarity)
H4CHR_03289	ENOG4105CHM	Aminotransferase
H4CHR_03290	ENOG4107YD3	Thioesterase
H4CHR_03291	ENOG4105E02	MotA TolQ exbB proton channel
H4CHR_03292	ENOG4108ZZF	transport protein (ExbD)
H4CHR_03294	ENOG4105C0B	DNA polymerase III (alpha subunit)
H4CHR_03295	ENOG4105C72	UPF0176 protein
H4CHR_03296	ENOG4105EUB	pirin domain protein
H4CHR_03298	ENOG4108VBZ	doxx family
H4CHR_03301	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
H4CHR_03302	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
H4CHR_03303	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
H4CHR_03305	ENOG4105CE2	Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding
H4CHR_03308	ENOG4107RQ2	Cytochrome c oxidase, subunit I
H4CHR_03310	ENOG4107QZ7	Cellulose synthase catalytic subunit
H4CHR_03311	ENOG4107EEX	Cellulose synthase regulator protein
H4CHR_03312	ENOG4105K2Z	endo-1,4-d-glucanase (EC 3.2.1.4)
H4CHR_03313	ENOG4105EJG	cellulose synthase
H4CHR_03316	ENOG4105FDF	Could be involved in DNA repair (By similarity)
H4CHR_03318	ENOG4105C8Q	Methyl-accepting chemotaxis
H4CHR_03323	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
H4CHR_03324	ENOG4108Z6B	deaminase
H4CHR_03329	ENOG4108ZXC	Two component transcriptional regulator, luxr family
H4CHR_03330	ENOG4105BZU	Histidine kinase
H4CHR_03332	ENOG4105KF3	Short-chain dehydrogenase reductase Sdr
H4CHR_03333	ENOG4105DE9	3-keto-5-aminohexanoate cleavage enzyme
H4CHR_03334	ENOG4108IV0	ABC, transporter
H4CHR_03335	ENOG4105C0Z	ABC transporter
H4CHR_03337	ENOG4105C32	Amino acid ABC transporter (Permease)
H4CHR_03339	ENOG4105CHR	reductase
H4CHR_03341	ENOG4105EBR	Carboxylesterase
H4CHR_03344	ENOG4105CD5	CoA-binding domain protein
H4CHR_03345	ENOG4105WH1	Two component transcriptional regulator luxr family
H4CHR_03348	ENOG4105CSH	Transporter
H4CHR_03349	ENOG4105E2S	oxidase) subunit II
H4CHR_03350	ENOG4105BZ9	Cytochrome C oxidase, subunit I
H4CHR_03351	ENOG4105CCU	oxidase (Subunit III)
H4CHR_03352	ENOG41090KH	cytochrome o ubiquinol oxidase (subunit iv)
H4CHR_03353	ENOG4108R6F	Surfeit locus 1 family protein
H4CHR_03354	ENOG4105TX3	Histidine kinase
H4CHR_03355	ENOG4108UYB	regulatoR
H4CHR_03357	ENOG4105FC8	fad dependent oxidoreductase
H4CHR_03365	ENOG4105KME	endoribonuclease L-psp
H4CHR_03366	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
H4CHR_03369	ENOG4105C4Y	ABC transporter
H4CHR_03370	ENOG4107RCV	ABC transporter, permease
H4CHR_03372	ENOG4107SM8	Adenylate Guanylate cyclase
H4CHR_03373	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
H4CHR_03374	ENOG4107F9Y	LysR family transcriptional regulator
H4CHR_03380	ENOG4105C5I	Dehydrogenase
H4CHR_03382	ENOG4105CBN	LysR family transcriptional regulator
H4CHR_03384	ENOG41061H0	Monooxygenase
H4CHR_03386	ENOG4105D5U	fad dependent oxidoreductase
H4CHR_03390	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
H4CHR_03393	ENOG41084M5	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
H4CHR_03394	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
H4CHR_03401	ENOG4105MP9	class II Aldolase
H4CHR_03402	ENOG4105FP9	thiamine pyrophosphate
H4CHR_03403	ENOG4105C26	Dehydrogenase
H4CHR_03407	ENOG4108UKV	benzoate 1,2-dioxygenase
H4CHR_03414	ENOG4105ETT	transcriptional Regulator, LysR family
H4CHR_03416	ENOG4107EFR	Flavocytochrome c
H4CHR_03417	ENOG4105C26	Dehydrogenase
H4CHR_03419	ENOG4105EQ2	LysR family Transcriptional regulator
H4CHR_03421	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
H4CHR_03427	ENOG4105CQB	FAD linked oxidase domain protein
H4CHR_03428	ENOG4107RAW	3-carboxy-cis-cis-muconate cycloisomerase
H4CHR_03430	ENOG4105KHC	sulfurtransferase
H4CHR_03433	ENOG4107ZN8	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
H4CHR_03434	ENOG4105F8V	Hydrolase, tatD family
H4CHR_03435	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
H4CHR_03436	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
H4CHR_03439	ENOG4108Z1B	Cyclase dehydrase
H4CHR_03440	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
H4CHR_03447	ENOG4105CI3	gtp-binding protein typa
H4CHR_03448	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
H4CHR_03449	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
H4CHR_03451	ENOG4105CHV	Transcription elongation factor NusA
H4CHR_03452	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
H4CHR_03453	ENOG4105CBP	Major Facilitator
H4CHR_03454	ENOG4108JQ5	ABC transporter
H4CHR_03455	ENOG4108IYQ	Binding-protein-dependent transport systems inner membrane component
H4CHR_03456	ENOG4108I5X	binding-protein-dependent transport systems inner membrane Component
H4CHR_03458	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
H4CHR_03462	ENOG4105CXN	decarboxylase
H4CHR_03467	ENOG4105CP9	extracellular ligand-binding receptor
H4CHR_03470	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
H4CHR_03474	ENOG4107R11	Transcriptional regulator
H4CHR_03475	ENOG4105CHM	Aminotransferase
H4CHR_03477	ENOG4105CQ7	ATP-dependent helicase
H4CHR_03478	ENOG4108EKC	n-acetylglutamate synthase
H4CHR_03479	ENOG4105CHM	Aminotransferase
H4CHR_03480	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
H4CHR_03481	ENOG4105CZX	twitching motility protein
H4CHR_03482	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
H4CHR_03483	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
H4CHR_03484	ENOG4105C5H	ABC transporter
H4CHR_03490	ENOG4107EFR	Flavocytochrome c
H4CHR_03496	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
H4CHR_03497	ENOG4105DAB	fumarate reductase succinate dehydrogenase flavoprotein domain protein
H4CHR_03503	ENOG4105EBM	Alpha Beta Hydrolase Fold protein
H4CHR_03505	ENOG4105CUZ	uba thif-type nad fad binding protein
H4CHR_03507	ENOG4105KCK	Peptidoglycan-associated lipoprotein
H4CHR_03508	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
H4CHR_03509	ENOG4105BZ1	(ABC) transporter
H4CHR_03510	ENOG4105C03	ribonuclease
H4CHR_03511	ENOG4108Z03	MAF-like protein
H4CHR_03512	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
H4CHR_03513	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
H4CHR_03514	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
H4CHR_03515	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
H4CHR_03516	ENOG4105C12	Phosphoribosylglycinamide synthetase
H4CHR_03517	ENOG4105CDY	transcriptional regulatory protein
H4CHR_03529	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
H4CHR_03532	ENOG4105D7A	ATP-binding protein
H4CHR_03533	ENOG4108ZJD	Protein of unknown function (DUF1109)
H4CHR_03534	ENOG4105NCT	RNA Polymerase
H4CHR_03536	ENOG4105E18	UPF0276 protein
H4CHR_03541	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
H4CHR_03542	ENOG4107TFB	basic membrane
H4CHR_03543	ENOG4108JQ9	ABC transporter
H4CHR_03544	ENOG4105UIB	(ABC) transporter
H4CHR_03546	ENOG4105DZC	cytosine deaminase
H4CHR_03547	ENOG4105CJB	Exodeoxyribonuclease I
H4CHR_03548	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
H4CHR_03549	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
H4CHR_03550	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
H4CHR_03554	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
H4CHR_03555	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
H4CHR_03557	ENOG4108ZZF	transport protein (ExbD)
H4CHR_03558	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
H4CHR_03559	ENOG4105W49	UPF0434 protein
H4CHR_03560	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
H4CHR_03561	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
H4CHR_03564	ENOG4107RB3	L-asparaginase
H4CHR_03565	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
H4CHR_03567	ENOG4108JQ1	Dehydrogenase
H4CHR_03568	ENOG4105F27	Major Facilitator
H4CHR_03570	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
H4CHR_03571	ENOG4108UKI	Enoyl-CoA hydratase
H4CHR_03576	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
H4CHR_03577	ENOG4105EEI	dihydropteroate synthase
H4CHR_03578	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
H4CHR_03579	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
H4CHR_03580	ENOG4105HBR	Rna-binding protein
H4CHR_03583	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
H4CHR_03585	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
H4CHR_03588	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
H4CHR_03589	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
H4CHR_03590	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
H4CHR_03591	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
H4CHR_03592	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
H4CHR_03594	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
H4CHR_03595	ENOG4105DZP	Membrane-associated zinc metalloprotease
H4CHR_03596	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
H4CHR_03597	ENOG4105KNE	Phosphatidate cytidylyltransferase
H4CHR_03598	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
H4CHR_03599	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
H4CHR_03600	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
H4CHR_03601	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
H4CHR_03602	ENOG4105CE9	30S ribosomal protein S2
H4CHR_03604	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
H4CHR_03605	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
H4CHR_03606	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
H4CHR_03607	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
H4CHR_03609	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
H4CHR_03610	ENOG4108NVM	synthesis repressor PhaR
H4CHR_03613	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
H4CHR_03614	ENOG4105DTD	Dehydrogenase
H4CHR_03618	ENOG4105E0F	Histidine kinase
H4CHR_03619	ENOG4108ECM	Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl- D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2- phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4- cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF) (By similarity)
H4CHR_03620	ENOG4108ECM	Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl- D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2- phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4- cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF) (By similarity)
H4CHR_03621	ENOG4108JA2	transcriptioN-repair coupling factor
H4CHR_03622	ENOG4105EAC	phosphoserine phosphatase
H4CHR_03627	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
H4CHR_03628	ENOG4105CSM	endonuclease III
H4CHR_03631	ENOG4108UHF	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
H4CHR_03632	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
H4CHR_03633	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
H4CHR_03634	ENOG4105ETP	RND efflux system, outer membrane lipoprotein
H4CHR_03636	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
H4CHR_03639	ENOG4105CIH	Imidazole acetol-phosphate transaminase
H4CHR_03641	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
H4CHR_03642	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
H4CHR_03643	ENOG4105EHG	Permease protein
H4CHR_03645	ENOG4108YZT	Adenosylcobinamide kinase
H4CHR_03646	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
H4CHR_03649	ENOG4105HF0	Membrane
H4CHR_03651	ENOG4105CEY	Amp-dependent synthetase and ligase
H4CHR_03655	ENOG4105DRR	Transcriptional regulator, GntR family
H4CHR_03657	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
H4CHR_03658	ENOG4106NZI	LysR family Transcriptional regulator
H4CHR_03659	ENOG4105C01	Dihydroxy-acid dehydratase
H4CHR_03665	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
H4CHR_03666	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
H4CHR_03670	ENOG4105DQE	DNA ligase
H4CHR_03680	ENOG4105DEI	Mannitol dehydrogenase
H4CHR_03681	ENOG4105CHR	reductase
H4CHR_03682	ENOG4105EQD	regulatoR
H4CHR_03683	ENOG4105CMG	Carbohydrate kinase
H4CHR_03686	ENOG4105C0H	protease
H4CHR_03687	ENOG4105DHQ	Histidine kinase
H4CHR_03688	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
H4CHR_03689	ENOG4107HP6	Transcriptional regulator
H4CHR_03690	ENOG41072AC	4-hydroxybenzoate 3-monooxygenase
H4CHR_03692	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
H4CHR_03693	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
H4CHR_03694	ENOG41069M3	Transcriptional regulator
H4CHR_03695	ENOG41061WM	D-Alanyl-D-Alanine
H4CHR_03696	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
H4CHR_03697	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
H4CHR_03698	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
H4CHR_03699	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
H4CHR_03700	ENOG4108ZP8	Acetolactate synthase small subunit
H4CHR_03701	ENOG4105C7K	acetolactate synthase
H4CHR_03706	ENOG41080IJ	Diacylglycerol kinase
H4CHR_03707	ENOG4108URH	decarboxylase
H4CHR_03708	ENOG4108YZA	Nitrogen regulatory protein pii
H4CHR_03710	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
H4CHR_03711	ENOG4105F0N	pyrophosphate phospho-hydrolase
H4CHR_03716	ENOG4107RZC	phospholipase d
H4CHR_03722	ENOG4105JN3	extra-cytoplasmic solute receptor family protein
H4CHR_03727	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
H4CHR_03728	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
H4CHR_03729	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
H4CHR_03731	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
H4CHR_03733	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
H4CHR_03734	ENOG4105E9H	Lytic Murein transglycosylase
H4CHR_03735	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
H4CHR_03737	ENOG4105D2X	ABC transporter substrate-binding protein
H4CHR_03739	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
H4CHR_03740	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
H4CHR_03741	ENOG4107QMP	dna polymerase iii subunits gamma and tau
H4CHR_03757	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
H4CHR_03758	ENOG4105K63	Thioredoxin
H4CHR_03759	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
H4CHR_03760	ENOG4105D9R	oxidoreductase
H4CHR_03761	ENOG4105NRA	50s ribosomal protein l31 type b
H4CHR_03763	ENOG4107QI1	Mate efflux family protein
H4CHR_03764	ENOG4105BZU	Histidine kinase
H4CHR_03765	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
H4CHR_03767	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
H4CHR_03768	ENOG4105E2Z	phosphate ABC transporter (Permease
H4CHR_03769	ENOG4105C8U	phosphate abc transporter
H4CHR_03770	ENOG4107QMV	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
H4CHR_03771	ENOG4105C9X	ppx gppa phosphatase
H4CHR_03773	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
H4CHR_03775	ENOG4108JU3	Alkyl hydroperoxide reductase
H4CHR_03776	ENOG4105CYM	Glutathione S-transferase
H4CHR_03785	ENOG4107S8C	mandelate racemase muconate lactonizing
H4CHR_03787	ENOG4108UKI	Enoyl-CoA hydratase
H4CHR_03788	ENOG4105C1G	acyl-Coa dehydrogenase
H4CHR_03789	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
H4CHR_03793	ENOG4107QRI	Phosphoketolase
H4CHR_03795	ENOG4105C0H	protease
H4CHR_03798	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
H4CHR_03799	ENOG41080TK	Universal stress protein
H4CHR_03800	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
H4CHR_03802	ENOG4105CHR	reductase
H4CHR_03805	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
H4CHR_03806	ENOG4105BZU	Histidine kinase
H4CHR_03814	ENOG4105C1G	acyl-Coa dehydrogenase
H4CHR_03815	ENOG4105CC9	acyl-Coa dehydrogenase
H4CHR_03820	ENOG4105E39	Enoyl-CoA hydratase
H4CHR_03821	ENOG4105C26	Dehydrogenase
H4CHR_03822	ENOG4105C7K	acetolactate synthase
H4CHR_03833	ENOG4105CMW	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity)
H4CHR_03834	ENOG4105CY0	Metallo-Beta-Lactamase
H4CHR_03835	ENOG4105CD5	CoA-binding domain protein
H4CHR_03838	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
H4CHR_03841	ENOG4105DQQ	Major facilitator superfamily MFS_1
H4CHR_03842	ENOG4105CRU	nitrate reductase, alpha subunit
H4CHR_03843	ENOG4108IUE	nitrate reductase beta subunit
H4CHR_03844	ENOG4105R3A	Nitrate reductase
H4CHR_03845	ENOG4105D0D	Nitrate reductase 2, gamma subunit
H4CHR_03853	ENOG4105VG1	fes assembly suf system protein
H4CHR_03857	ENOG41062QD	Membrane
H4CHR_03858	ENOG4107QN1	sodium solute
H4CHR_03862	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
H4CHR_03863	ENOG4108IRC	dna polymerase iii
H4CHR_03864	ENOG4105D0S	secretion protein (HlyD
H4CHR_03868	ENOG4108IUN	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
H4CHR_03869	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
H4CHR_03875	ENOG41080HT	Transcriptional regulator, arsr family
H4CHR_03882	ENOG4107RZC	phospholipase d
H4CHR_03888	ENOG41080TK	Universal stress protein
H4CHR_03891	ENOG4107Y70	Heat shock protein
H4CHR_03894	ENOG41080TK	Universal stress protein
H4CHR_03897	ENOG4108YV4	Universal stress protein
H4CHR_03898	ENOG4105C0H	protease
H4CHR_03901	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
H4CHR_03909	ENOG41080TK	Universal stress protein
H4CHR_03911	ENOG4105D4P	Coproporphyrinogen iii oxidase
H4CHR_03912	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
H4CHR_03917	ENOG4105E2X	shikimate dehydrogenase
H4CHR_03919	ENOG4108IIG	CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons (By similarity)
H4CHR_03920	ENOG4105DAB	fumarate reductase succinate dehydrogenase flavoprotein domain protein
H4CHR_03921	ENOG4105CHR	reductase
H4CHR_03925	ENOG4108R85	Short chain dehydrogenase
H4CHR_03927	ENOG4105CHR	reductase
H4CHR_03929	ENOG4105CHR	reductase
H4CHR_03932	ENOG4105C0Z	ABC transporter
H4CHR_03933	ENOG4105C32	Amino acid ABC transporter (Permease)
H4CHR_03934	ENOG4105C6F	GntR Family Transcriptional Regulator
H4CHR_03935	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
H4CHR_03938	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
H4CHR_03942	ENOG4105C32	Amino acid ABC transporter (Permease)
H4CHR_03944	ENOG4105C0Z	ABC transporter
H4CHR_03945	ENOG4108IV0	ABC, transporter
H4CHR_03948	ENOG4105C26	Dehydrogenase
H4CHR_03949	ENOG4105CZ6	Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine (By similarity)
H4CHR_03951	ENOG4107R11	Transcriptional regulator
H4CHR_03953	ENOG4107EFR	Flavocytochrome c
H4CHR_03955	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
H4CHR_03958	ENOG4105DTQ	mandelate racemase muconate lactonizing
H4CHR_03961	ENOG4105C5I	Dehydrogenase
H4CHR_03963	ENOG4108IV0	ABC, transporter
H4CHR_03964	ENOG4105C0Z	ABC transporter
H4CHR_03966	ENOG4105C32	Amino acid ABC transporter (Permease)
H4CHR_03968	ENOG41066T0	asmA family
H4CHR_03973	ENOG41060WC	Enoyl-CoA hydratase
H4CHR_03976	ENOG4108MXC	l-carnitine dehydratase bile acid-inducible protein F
H4CHR_03980	ENOG4107YZX	Universal stress protein
H4CHR_03982	ENOG4105CCT	upf0313 protein
H4CHR_03983	ENOG410645S	MarR family Transcriptional regulator
H4CHR_03988	ENOG4107S2Z	UPF0761 membrane protein
H4CHR_03991	ENOG4105CPC	Aldo Keto reductase
H4CHR_03996	ENOG4105C2N	RNA methyltransferase TrmH family group 3
H4CHR_03997	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
H4CHR_03998	ENOG4108UJV	acyl-CoA thioesterase i
H4CHR_04000	ENOG4105C28	cystathionine
H4CHR_04003	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
H4CHR_04004	ENOG4105C49	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity)
H4CHR_04006	ENOG4105EPW	hflc protein
H4CHR_04007	ENOG4107QJR	hflk protein
H4CHR_04008	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
H4CHR_04009	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
H4CHR_04010	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
H4CHR_04011	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
H4CHR_04013	ENOG4105CUT	histidyl-tRNA synthetase
H4CHR_04014	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
H4CHR_04017	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
H4CHR_04018	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
H4CHR_04019	ENOG4105FE9	pseudouridine synthase
H4CHR_04020	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
H4CHR_04021	ENOG4105C34	Pseudouridine synthase
H4CHR_04022	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
H4CHR_04023	ENOG4105DVT	helicase
H4CHR_04027	ENOG4105D6Z	AFG1 family ATPase
H4CHR_04028	ENOG4107QN2	dihydrolipoyl dehydrogenase
H4CHR_04029	ENOG4105C7S	Dehydrogenase
H4CHR_04030	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
H4CHR_04032	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
H4CHR_04034	ENOG4108PTX	LysR family Transcriptional regulator
H4CHR_04037	ENOG4108JUA	Transcriptional regulator
H4CHR_04038	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
H4CHR_04039	ENOG41082A2	Alpha beta hydrolase
H4CHR_04041	ENOG4105ER2	Ompa motb domain protein
H4CHR_04045	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
H4CHR_04046	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
H4CHR_04048	ENOG4105D8V	Glucose sorbosone dehydrogenase
H4CHR_04049	ENOG4105K4H	Nlp p60 protein
H4CHR_04056	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
H4CHR_04057	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
H4CHR_04062	ENOG4107QN2	dihydrolipoyl dehydrogenase
H4CHR_04063	ENOG4107QSN	dihydrolipoamide acetyltransferase
H4CHR_04064	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
H4CHR_04065	ENOG4105BZU	Histidine kinase
H4CHR_04066	ENOG4108ZXC	Two component transcriptional regulator, luxr family
H4CHR_04067	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
H4CHR_04068	ENOG4105DGW	oligopeptidase A
H4CHR_04070	ENOG4105E66	phosphoriboisomerase A
H4CHR_04071	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
H4CHR_04074	ENOG4105D5U	fad dependent oxidoreductase
H4CHR_04077	ENOG4107RZZ	dna polymerase iii epsilon subunit
H4CHR_04078	ENOG4108ZIT	Ferredoxin, 2FE-2S
H4CHR_04079	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
H4CHR_04082	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
H4CHR_04083	ENOG4105C3J	Cysteine desulfurase
H4CHR_04084	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
H4CHR_04086	ENOG4105CGF	Aromatic amino acid aminotransferase
H4CHR_04088	ENOG4108R3D	Electron transport complex
H4CHR_04092	ENOG4107QX3	carboxylase
H4CHR_04093	ENOG4105DJT	lAO AO transport system ATPase
H4CHR_04095	ENOG4105DRR	Transcriptional regulator, GntR family
H4CHR_04099	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
H4CHR_04100	ENOG4107QRT	dEAD DEAH box helicase
H4CHR_04101	ENOG4105BZU	Histidine kinase
H4CHR_04107	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
H4CHR_04108	ENOG4105CK2	sodium dicarboxylate symporter
H4CHR_04109	ENOG4105CHR	reductase
H4CHR_04111	ENOG4105CHU	acetyl-coa acetyltransferase
H4CHR_04112	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
H4CHR_04114	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
H4CHR_04118	ENOG4108RH0	Crea protein
H4CHR_04119	ENOG4108K5P	(LipO)protein
H4CHR_04120	ENOG4107RZC	phospholipase d
H4CHR_04123	ENOG4105F04	LysR family Transcriptional regulator
H4CHR_04124	ENOG4105QG4	Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity)
H4CHR_04129	ENOG4105CHR	reductase
H4CHR_04131	ENOG410900P	UPF0336 protein
H4CHR_04133	ENOG4108UKI	Enoyl-CoA hydratase
H4CHR_04134	ENOG4105CEY	Amp-dependent synthetase and ligase
H4CHR_04135	ENOG4105C1G	acyl-Coa dehydrogenase
H4CHR_04137	ENOG4105E39	Enoyl-CoA hydratase
H4CHR_04141	ENOG4105C32	Amino acid ABC transporter (Permease)
H4CHR_04142	ENOG4108IV0	ABC, transporter
H4CHR_04143	ENOG4105C0Z	ABC transporter
H4CHR_04144	ENOG4108KQI	regulatory protein luxr
H4CHR_04147	ENOG4105ETT	transcriptional Regulator, LysR family
H4CHR_04148	ENOG4108K3A	Glutathione S-transferase
H4CHR_04151	ENOG4105FDP	GntR family transcriptional regulator
H4CHR_04157	ENOG4105CEY	Amp-dependent synthetase and ligase
H4CHR_04158	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
H4CHR_04159	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
H4CHR_04168	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
H4CHR_04169	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
H4CHR_04176	ENOG4105DVF	Cytosine-specific methyltransferase
H4CHR_04190	ENOG4106NZI	LysR family Transcriptional regulator
H4CHR_04194	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
H4CHR_04196	ENOG4108JQ6	ABC transporter
H4CHR_04197	ENOG4105MP9	class II Aldolase
H4CHR_04198	ENOG4108RBJ	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
H4CHR_04201	ENOG4105DVW	rieske (2Fe-2S)
H4CHR_04203	ENOG4105C26	Dehydrogenase
H4CHR_04204	ENOG4108JPW	Aminotransferase
H4CHR_04206	ENOG4105JPG	D-isomer specific 2-hydroxyacid dehydrogenase
H4CHR_04207	ENOG4105MP9	class II Aldolase
H4CHR_04216	ENOG4105DND	Transcriptional regulator
H4CHR_04219	ENOG41082A2	Alpha beta hydrolase
H4CHR_04220	ENOG4105DVW	rieske (2Fe-2S)
H4CHR_04222	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
H4CHR_04225	ENOG4105DVW	rieske (2Fe-2S)
H4CHR_04233	ENOG4108UAU	isochorismatase
H4CHR_04243	ENOG4107QJE	Chromosome Partitioning Protein
H4CHR_04253	ENOG4105FA0	parb-like partition protein
H4CHR_04256	ENOG4105W5Q	DNA repair protein (RadC
H4CHR_04260	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
H4CHR_04261	ENOG4105ETE	Transcriptional regulator (LacI family
H4CHR_04262	ENOG4107XWI	flavin reductase domain protein, FMN-binding
H4CHR_04264	ENOG4105D7T	ABC transporter
H4CHR_04266	ENOG4105Y36	Binding-protein-dependent transport systems, inner membrane component
H4CHR_04267	ENOG4105E39	Enoyl-CoA hydratase
H4CHR_04272	ENOG4105C26	Dehydrogenase
H4CHR_04274	ENOG4105C10	Electron transfer flavoprotein
H4CHR_04275	ENOG4105BZJ	Electron transfer flavoprotein
H4CHR_04278	ENOG4105E39	Enoyl-CoA hydratase
H4CHR_04281	ENOG4105CEY	Amp-dependent synthetase and ligase
H4CHR_04284	ENOG4105HEI	LysR family (Transcriptional regulator
H4CHR_04285	ENOG4105DFP	Integrase
H4CHR_04288	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
H4CHR_04290	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
H4CHR_04291	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
H4CHR_04292	ENOG4105VJV	50s ribosomal protein L35
H4CHR_04293	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
H4CHR_04294	ENOG4105C22	threonyL-tRNA synthetase
H4CHR_04295	ENOG4108I9X	Isocitrate lyase
H4CHR_04300	ENOG4108W9H	Tetr family transcriptional regulator
H4CHR_04309	ENOG4107TTA	Xylose isomerase domain protein TIM barrel
H4CHR_04313	ENOG410908U	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
H4CHR_04317	ENOG4105CHH	sulfate transporter
H4CHR_04318	ENOG4108YZN	class I peptide chain release factor
H4CHR_04321	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
H4CHR_04325	ENOG4106NZI	LysR family Transcriptional regulator
H4CHR_04327	ENOG4108ZAF	Molybdopterin
H4CHR_04328	ENOG4105M00	molybdopterin converting factor, subunit 1
H4CHR_04329	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
H4CHR_04330	ENOG4105FNP	Molybdopterin-guanine dinucleotide biosynthesis protein b
H4CHR_04331	ENOG4105D98	threonine synthase
H4CHR_04332	ENOG4105D6E	homoserine dehydrogenase
H4CHR_04333	ENOG4105CHM	Aminotransferase
H4CHR_04335	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
H4CHR_04336	ENOG4108IAB	Phoh family
H4CHR_04339	ENOG4105CDU	Replicative dna helicase
H4CHR_04340	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
H4CHR_04341	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
H4CHR_04342	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
H4CHR_04344	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
H4CHR_04345	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
H4CHR_04348	ENOG4108JU3	Alkyl hydroperoxide reductase
H4CHR_04349	ENOG4105D3R	alkyl hydroperoxide reductase
H4CHR_04350	ENOG4108UQY	Iron-storage protein
H4CHR_04353	ENOG4105M8F	Biopolymer transport protein exbD tolR
H4CHR_04355	ENOG4108ZJF	Glcg protein
H4CHR_04356	ENOG4108MN8	Membrane
H4CHR_04357	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
H4CHR_04358	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
H4CHR_04359	ENOG4108K5P	(LipO)protein
H4CHR_04360	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
H4CHR_04361	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
H4CHR_04372	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
H4CHR_04415	ENOG4107RHI	Cytosine-specific methyltransferase
H4CHR_04422	ENOG4108XTP	Transcriptional regulator
H4CHR_04433	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
H4CHR_04443	ENOG4107TF3	peptidylprolyl cis-trans isomerase
H4CHR_04446	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
H4CHR_04448	ENOG4106855	Competence protein
H4CHR_04458	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
H4CHR_04460	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
H4CHR_04464	ENOG4105C5I	Dehydrogenase
H4CHR_04466	ENOG4107RH7	Nicotinate phosphoribosyltransferase
H4CHR_04467	ENOG4105VDW	Csbd family
H4CHR_04470	ENOG4105DGU	Histone deacetylase
H4CHR_04471	ENOG4108WFY	phasin family
H4CHR_04473	ENOG4107S2Z	UPF0761 membrane protein
H4CHR_04474	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
H4CHR_04475	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
H4CHR_04476	ENOG4105C2C	drug resistance transporter, Bcr CflA
H4CHR_04479	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
H4CHR_04480	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
H4CHR_04484	ENOG4108IV0	ABC, transporter
H4CHR_04485	ENOG4105C0Z	ABC transporter
H4CHR_04490	ENOG4108WYP	Transcriptional regulator
H4CHR_04494	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
H4CHR_04497	ENOG4105E90	ABC transporter
H4CHR_04498	ENOG4105C26	Dehydrogenase
H4CHR_04499	ENOG4105UVJ	5-dehydro-4-deoxyglucarate dehydratase
H4CHR_04501	ENOG4107YCY	Transcriptional regulator
H4CHR_04502	ENOG4105E9Z	Nad-dependent epimerase dehydratase
H4CHR_04503	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
H4CHR_04505	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
H4CHR_04506	ENOG4105HHQ	6-phosphogluconolactonase (EC 3.1.1.31)
H4CHR_04507	ENOG4105CTX	dehydratase
H4CHR_04508	ENOG4105CHR	reductase
H4CHR_04509	ENOG4105HHQ	6-phosphogluconolactonase (EC 3.1.1.31)
H4CHR_04511	ENOG4105DJ4	phosphatidylserine decarboxylase
H4CHR_04513	ENOG4108V1T	peptidylprolyl cis-trans isomerase
H4CHR_04514	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
H4CHR_04515	ENOG4105CFG	Acts as a chaperone (By similarity)
H4CHR_04516	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
H4CHR_04517	ENOG41073TP	transcriptional regulator
H4CHR_04518	ENOG4105ERH	Fumarylacetoacetate hydrolase
H4CHR_04520	ENOG4105CYN	Serine protein kinase
H4CHR_04521	ENOG4106AKX	UPF0229 protein
H4CHR_04522	ENOG4105ED1	spovr family
H4CHR_04523	ENOG4108R3E	Dna-3-methyladenine glycosylase i
H4CHR_04524	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
H4CHR_04525	ENOG4107YCY	Transcriptional regulator
H4CHR_04530	ENOG4107QPD	alcohol dehydrogenase
H4CHR_04532	ENOG4105C4W	S-formylglutathione hydrolase
H4CHR_04533	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
H4CHR_04536	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
H4CHR_04539	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
H4CHR_04541	ENOG4107RZC	phospholipase d
H4CHR_04542	ENOG41080XP	Cbs domain
H4CHR_04544	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
H4CHR_04545	ENOG4105K4T	epimerase
H4CHR_04546	ENOG4105K63	Thioredoxin
H4CHR_04547	ENOG4107S2Z	UPF0761 membrane protein
H4CHR_04549	ENOG4105CQB	FAD linked oxidase domain protein
H4CHR_04550	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
H4CHR_04560	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
H4CHR_04561	ENOG4105D7T	ABC transporter
H4CHR_04562	ENOG4105C2J	ABC transporter
H4CHR_04564	ENOG4105CNN	ABC, transporter
H4CHR_04565	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
H4CHR_04566	ENOG4105CNN	ABC, transporter
H4CHR_04569	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
H4CHR_04570	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
H4CHR_04573	ENOG4105C32	Amino acid ABC transporter (Permease)
H4CHR_04576	ENOG4105CGK	Exodeoxyribonuclease III
H4CHR_04578	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
H4CHR_04579	ENOG4105CUX	Signal transduction histidine kinase
H4CHR_04582	ENOG4107TH8	cina domain protein
H4CHR_04587	ENOG4105I08	Pseudouridine synthase
H4CHR_04589	ENOG4106R49	Methyltransferase
H4CHR_04592	ENOG4105E6M	Sulphatase-modifying factor protein
H4CHR_04593	ENOG4107QRH	Arylsulfatase (Ec 3.1.6.1)
H4CHR_04594	ENOG4105CPQ	Dehydrogenase
H4CHR_04597	ENOG4105ERH	Fumarylacetoacetate hydrolase
H4CHR_04602	ENOG4107R11	Transcriptional regulator
H4CHR_04605	ENOG4105CQB	FAD linked oxidase domain protein
H4CHR_04606	ENOG4105C26	Dehydrogenase
H4CHR_04608	ENOG4105ERH	Fumarylacetoacetate hydrolase
H4CHR_04609	ENOG41084M5	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
H4CHR_04611	ENOG4105JN3	extra-cytoplasmic solute receptor family protein
H4CHR_04612	ENOG4105MP9	class II Aldolase
H4CHR_04613	ENOG4107RSM	transcriptional regulator
H4CHR_04616	ENOG4105JN3	extra-cytoplasmic solute receptor family protein
H4CHR_04617	ENOG4105ENH	Sulfatase
H4CHR_04619	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
H4CHR_04620	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
H4CHR_04621	ENOG4105UYK	outer membrane protein a
H4CHR_04622	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
H4CHR_04624	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
H4CHR_04625	ENOG4105CQC	Prephenate dehydratase
H4CHR_04627	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
H4CHR_04628	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
H4CHR_04631	ENOG4105CFV	Tetratricopeptide repeat protein
H4CHR_04635	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
H4CHR_04636	ENOG4107Z6W	Protein CrcB homolog
H4CHR_04637	ENOG4105D65	subunit l
H4CHR_04638	ENOG4108ZE9	Monovalent cation H antiporter subunit C
H4CHR_04639	ENOG4107R4Z	monovalent cation h antiporter subunit d
H4CHR_04641	ENOG4105W4C	monovalent cation H antiporter subunit F
H4CHR_04642	ENOG4105KJM	monovalent cation h antiporter subunit g
H4CHR_04649	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
H4CHR_04655	ENOG4107T8Q	Glycosyl transferase (Group 1
H4CHR_04657	ENOG4105CPQ	Dehydrogenase
H4CHR_04659	ENOG4108YYC	ycei family
H4CHR_04662	ENOG4107P0T	Selenium-dependent molybdenum hydroxylase system protein, YqeB family
H4CHR_04665	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
H4CHR_04671	ENOG4108IJ0	Aspartate ammonia-lyase
H4CHR_04672	ENOG4105MDH	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
H4CHR_04673	ENOG4105F4R	Transcriptional regulator mode
H4CHR_04674	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
H4CHR_04675	ENOG4105E0C	molybdate abc transporter
H4CHR_04676	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
H4CHR_04679	ENOG4108JZF	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
H4CHR_04680	ENOG4105F0N	pyrophosphate phospho-hydrolase
H4CHR_04681	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
H4CHR_04684	ENOG4108JJB	ABC transporter
H4CHR_04686	ENOG4105F4R	Transcriptional regulator mode
H4CHR_04690	ENOG4108IV0	ABC, transporter
H4CHR_04691	ENOG4105C0Z	ABC transporter
H4CHR_04694	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
H4CHR_04695	ENOG4108ZA2	phenylacetate-CoA oxygenase PaaJ subunit
H4CHR_04696	ENOG4105D9S	phenylacetate-CoA oxygenase PaaI subunit
H4CHR_04697	ENOG4105N76	Phenylacetate-CoA oxygenase, subunit
H4CHR_04698	ENOG4105CRS	phenylacetate-CoA oxygenase PaaG subunit
H4CHR_04700	ENOG4108ZJI	phenylacetic acid degradation protein
H4CHR_04701	ENOG4108UKI	Enoyl-CoA hydratase
H4CHR_04702	ENOG4108Z0R	Transferase
H4CHR_04703	ENOG4108IG5	Transcriptional regulator
H4CHR_04704	ENOG4105E46	N-alpha,N-alpha,N-alpha-trimethyl-L-histidine metabolic process
H4CHR_04706	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
H4CHR_04708	ENOG4105CH5	extracellular solute-binding protein, family 7
H4CHR_04709	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
H4CHR_04710	ENOG4105CTB	Polyprenyl synthetase
H4CHR_04711	ENOG41082UU	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
H4CHR_04714	ENOG4105KHC	sulfurtransferase
H4CHR_04716	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
H4CHR_04719	ENOG4105WKW	Pfam:DUF1458
H4CHR_04722	ENOG4105CDZ	Carboxymethylenebutenolidase (EC 3.1.1.45)
H4CHR_04724	ENOG4107RP9	extracellular solute-binding protein, family 3
H4CHR_04725	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
H4CHR_04728	ENOG4105C2M	dna polymerase I
H4CHR_04730	ENOG4105CUV	Homoserine Kinase
H4CHR_04732	ENOG4105C4R	Atp-dependent dna helicase
H4CHR_04734	ENOG4107SJ1	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides (By similarity)
H4CHR_04736	ENOG4105CHR	reductase
H4CHR_04737	ENOG4105CHU	acetyl-coa acetyltransferase
H4CHR_04740	ENOG4105C1J	atp-dependent rna helicase
H4CHR_04741	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
H4CHR_04742	ENOG4105D0M	Protease HtpX homolog
H4CHR_04743	ENOG41090A4	Pterin carbinolamine dehydratase
H4CHR_04744	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
H4CHR_04745	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
H4CHR_04746	ENOG4105CIH	Imidazole acetol-phosphate transaminase
H4CHR_04747	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
H4CHR_04748	ENOG4105P8F	nudix hydrolase
H4CHR_04749	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
H4CHR_04750	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
H4CHR_04751	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
H4CHR_04752	ENOG4105K5M	30s ribosomal protein S16
H4CHR_04755	ENOG4107QXV	Phosphate transporter
H4CHR_04756	ENOG4107GRR	phosphate transport regulator
H4CHR_04758	ENOG4105DJ0	Poly(A) Polymerase
H4CHR_04759	ENOG4108KZ1	Mediates the interaction of DNA replication inititator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN). Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinititation, a process called regulatory inhibition of DnaA or RIDA (By similarity)
H4CHR_04760	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
H4CHR_04762	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
H4CHR_04766	ENOG4105CJR	Integral membrane protein (MviN
H4CHR_04767	ENOG41082GY	Binds directly to 16S ribosomal RNA (By similarity)
H4CHR_04769	ENOG4105C8Y	Acetylornithine aminotransferase
H4CHR_04770	ENOG4105DBV	ornithine carbamoyltransferase
H4CHR_04771	ENOG4105C26	Dehydrogenase
H4CHR_04772	ENOG4107VWA	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation (By similarity)
H4CHR_04774	ENOG4105HJ8	Catalyzes the oxidative cleavage of the L-tryptophan (L- Trp) pyrrole ring (By similarity)
H4CHR_04776	ENOG4105MSY	salicylate hydroxylase
H4CHR_04778	ENOG4105CE1	Ferrous iron transport protein b
H4CHR_04780	ENOG4107QM5	aconitate hydratase
H4CHR_04783	ENOG4107QIJ	Aconitate hydratase 2
H4CHR_04785	ENOG4105CI0	Citrate lyase
H4CHR_04786	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
H4CHR_04787	ENOG4105D9Z	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
H4CHR_04788	ENOG4105FDP	GntR family transcriptional regulator
H4CHR_04791	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
H4CHR_04792	ENOG4105E33	succinate dehydrogenase
H4CHR_04793	ENOG41060IS	Flavinator of succinate dehydrogenase
H4CHR_04794	ENOG4105BZN	citrate synthase
H4CHR_04797	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
H4CHR_04798	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
H4CHR_04799	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
H4CHR_04800	ENOG4107QJH	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
H4CHR_04802	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
H4CHR_04803	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
H4CHR_04804	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
H4CHR_04805	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
H4CHR_04806	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
H4CHR_04807	ENOG4108VIA	integral membrane protein
H4CHR_04809	ENOG4105CRK	lysyL-tRNA synthetase
H4CHR_04810	ENOG4105R8A	Heat shock protein
H4CHR_04811	ENOG4108VKG	metal-dependent hydrolase
H4CHR_04812	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
H4CHR_04813	ENOG4105KJV	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
H4CHR_04814	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
H4CHR_04815	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
H4CHR_04816	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
H4CHR_04817	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
H4CHR_04819	ENOG4105C3F	Signal peptidase i
H4CHR_04820	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
H4CHR_04821	ENOG4105C0H	protease
H4CHR_04824	ENOG4105EMN	RNA polymerase sigma factor
H4CHR_04825	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
H4CHR_04826	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
H4CHR_04827	ENOG4105CHR	reductase
H4CHR_04828	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
H4CHR_04829	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
H4CHR_04830	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
H4CHR_04831	ENOG4105VGS	50s ribosomal protein l32
H4CHR_04832	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
H4CHR_04833	ENOG4108UHJ	MAF-like protein
H4CHR_04834	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
H4CHR_04835	ENOG4106UW1	Major Facilitator superfamily
H4CHR_04836	ENOG4108E8C	) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
H4CHR_04839	ENOG4105EI2	Pseudouridine synthase
H4CHR_04840	ENOG4105C03	ribonuclease
H4CHR_04841	ENOG4105D3Q	Sugar transferase
H4CHR_04842	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
H4CHR_04843	ENOG4105C30	Nad-dependent epimerase dehydratase
H4CHR_04847	ENOG4106CD9	glycosyl transferase group 1
H4CHR_04854	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
H4CHR_04855	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
H4CHR_04856	ENOG410642W	LysR family Transcriptional regulator
H4CHR_04857	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
H4CHR_04861	ENOG4105C32	Amino acid ABC transporter (Permease)
H4CHR_04862	ENOG4108IV0	ABC, transporter
H4CHR_04863	ENOG4105C0Z	ABC transporter
H4CHR_04865	ENOG4106XMA	In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity)
H4CHR_04868	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
H4CHR_04869	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
H4CHR_04870	ENOG4105W8H	transhydrogenase (subunit alpha
H4CHR_04871	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
H4CHR_04872	ENOG4106XMA	In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity)
H4CHR_04873	ENOG41069HH	4-oxalocrotonate tautomerase
H4CHR_04879	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
H4CHR_04881	ENOG4108WYP	Transcriptional regulator
H4CHR_04883	ENOG4105CKI	cobalamin synthesis protein
H4CHR_04885	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
H4CHR_04887	ENOG4105DTQ	mandelate racemase muconate lactonizing
H4CHR_04895	ENOG4105CSD	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
H4CHR_04898	ENOG4105D1Q	UPF0246 protein
H4CHR_04900	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
H4CHR_04902	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
H4CHR_04903	ENOG4105E09	nadh pyrophosphatase
H4CHR_04904	ENOG4105C6T	cysteine synthase
H4CHR_04906	ENOG4105VFU	Rna-binding protein
H4CHR_04909	ENOG4105CK2	sodium dicarboxylate symporter
H4CHR_04912	ENOG4105WH1	Two component transcriptional regulator luxr family
H4CHR_04913	ENOG4105C0H	protease
H4CHR_04918	ENOG4108IV0	ABC, transporter
H4CHR_04919	ENOG4105C0Z	ABC transporter
H4CHR_04920	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
H4CHR_04921	ENOG4105C32	Amino acid ABC transporter (Permease)
H4CHR_04922	ENOG4105D1H	recombination factor protein RarA
H4CHR_04923	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
H4CHR_04924	ENOG4105CNU	cell division protein FtsK
H4CHR_04926	ENOG4105C3M	thioredoxin reductase
H4CHR_04927	ENOG4105KDC	50s ribosomal protein l28
H4CHR_04928	ENOG4105W0E	50S ribosomal protein L33
H4CHR_04931	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
H4CHR_04932	ENOG4105CC9	acyl-Coa dehydrogenase
H4CHR_04933	ENOG4105C1G	acyl-Coa dehydrogenase
H4CHR_04935	ENOG4105E39	Enoyl-CoA hydratase
H4CHR_04937	ENOG4105DTN	riboflavin biosynthesis protein ribF
H4CHR_04939	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
H4CHR_04940	ENOG4105EAM	Na Pi-cotransporter
H4CHR_04941	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
H4CHR_04944	ENOG4107SYB	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
H4CHR_04945	ENOG4108JQ7	(ABC) transporter
H4CHR_04948	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
H4CHR_04949	ENOG4107RNA	Nickel ABC transporter, periplasmic nickel-binding protein
H4CHR_04950	ENOG4105JQN	Transcriptional regulator
H4CHR_04951	ENOG4105CHR	reductase
H4CHR_04953	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
H4CHR_04957	ENOG4107QHF	type ii secretion system protein e
H4CHR_04958	ENOG4105I7M	spermidine synthase
H4CHR_04961	ENOG4105F8V	Hydrolase, tatD family
H4CHR_04962	ENOG4105C0H	protease
H4CHR_04963	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
H4CHR_04967	ENOG4105RQF	LysR family Transcriptional regulator
H4CHR_04969	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
H4CHR_04972	ENOG4106KNT	transcriptional regulator
H4CHR_04983	ENOG4105CAF	HipA N-terminal domain protein
H4CHR_04985	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
H4CHR_04988	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
H4CHR_04992	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
H4CHR_04993	ENOG4105BZU	Histidine kinase
H4CHR_04994	ENOG4108YZ9	Urea amidohydrolase subunit gamma
H4CHR_04996	ENOG4105KI2	Urea amidohydrolase subunit beta
H4CHR_04997	ENOG4105CQM	Urea amidohydrolase subunit alpha
H4CHR_05000	ENOG4105MMR	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly (By similarity)
H4CHR_05001	ENOG4108WKG	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
H4CHR_05002	ENOG4105E8T	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG (By similarity)
H4CHR_05004	ENOG4105E2B	Taurine dioxygenase
H4CHR_05007	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
H4CHR_05009	ENOG4108Z9W	Outer membrane porin
H4CHR_05011	ENOG4105C7K	acetolactate synthase
H4CHR_05019	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
H4CHR_05022	ENOG4105MP9	class II Aldolase
H4CHR_05024	ENOG4108I05	Binding-protein-dependent transport systems, inner membrane component
H4CHR_05026	ENOG4105E39	Enoyl-CoA hydratase
H4CHR_05028	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
H4CHR_05033	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
H4CHR_05040	ENOG4105CSA	Coproporphyrinogen iii oxidase
H4CHR_05041	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
H4CHR_05042	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
H4CHR_05044	ENOG4105D9P	serine threonine protein kinase
H4CHR_05045	ENOG4105DSJ	YicC domain protein
H4CHR_05046	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
H4CHR_05047	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
H4CHR_05048	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
H4CHR_05049	ENOG4108RRZ	Transcription elongation factor GreB
H4CHR_05051	ENOG4105IKQ	hydratase
H4CHR_05052	ENOG4105DIV	Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD( ) and coenzyme A. Is the final enzyme in the meta- cleavage pathway for the degradation of aromatic compounds (By similarity)
H4CHR_05053	ENOG4105DF3	Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta-cleavage pathway for the degradation of aromatic compounds (By similarity)
H4CHR_05057	ENOG4105GYP	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline (By similarity)
H4CHR_05058	ENOG4105DE9	3-keto-5-aminohexanoate cleavage enzyme
H4CHR_05059	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
H4CHR_05062	ENOG4105CEY	Amp-dependent synthetase and ligase
H4CHR_05072	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
H4CHR_05074	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
H4CHR_05075	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
H4CHR_05076	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
H4CHR_05077	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
H4CHR_05078	ENOG4105CEN	a g-specific adenine glycosylase
H4CHR_05079	ENOG410890F	Dynamin family
H4CHR_05080	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
H4CHR_05083	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
H4CHR_05085	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
H4CHR_05086	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
H4CHR_05087	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
H4CHR_05089	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
H4CHR_05091	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
H4CHR_05093	ENOG4108JQ7	(ABC) transporter
H4CHR_05094	ENOG4105DEF	Extracellular solute-binding protein, family 5
H4CHR_05095	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
H4CHR_05096	ENOG4107NQ8	LysR family Transcriptional regulator
H4CHR_05100	ENOG4108NIW	Leucine export protein LeuE
H4CHR_05102	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
H4CHR_05103	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
H4CHR_05104	ENOG4108KN7	Removes 5-oxoproline from various penultimate amino acid residues except L-proline (By similarity)
H4CHR_05105	ENOG4105E7W	lamb ycsf family protein
H4CHR_05106	ENOG4107R7A	Allophanate hydrolase subunit 2
H4CHR_05107	ENOG4105P4J	Allophanate hydrolase, subunit 1
H4CHR_05108	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
H4CHR_05109	ENOG4106H78	methyltransferase
H4CHR_05114	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
H4CHR_05116	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
H4CHR_05121	ENOG4107QS1	Cytochrome C Oxidase, Subunit III
H4CHR_05123	ENOG4105FT1	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I (By similarity)
H4CHR_05125	ENOG4105BZ9	Cytochrome C oxidase, subunit I
H4CHR_05128	ENOG4106T9E	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
H4CHR_05130	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
H4CHR_05133	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
H4CHR_05136	ENOG4105E9F	Enoyl-CoA hydratase
H4CHR_05141	ENOG4105CSU	acyl-Coa dehydrogenase
H4CHR_05145	ENOG4105CIF	Ornithine Cyclodeaminase
H4CHR_05146	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
H4CHR_05152	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
H4CHR_05154	ENOG4105CH5	extracellular solute-binding protein, family 7
H4CHR_05162	ENOG4105RE0	Asp Glu hydantoin racemase
H4CHR_05165	ENOG4108UAU	isochorismatase
H4CHR_05166	ENOG4105CHU	acetyl-coa acetyltransferase
H4CHR_05167	ENOG4107QNJ	CoA-transferase subunit B
H4CHR_05169	ENOG4107HP6	Transcriptional regulator
H4CHR_05170	ENOG4105K70	DNA-binding protein
H4CHR_05171	ENOG4105DIA	mandelate racemase muconate lactonizing
H4CHR_05178	ENOG4108TJN	glycosyl transferase group 1
H4CHR_05182	ENOG4105CEY	Amp-dependent synthetase and ligase
H4CHR_05184	ENOG4105C2C	drug resistance transporter, Bcr CflA
H4CHR_05186	ENOG4105CHR	reductase
H4CHR_05187	ENOG4105CBK	multidrug resistance protein
H4CHR_05190	ENOG4105CS1	NAD(P)H quinone oxidoreductase
H4CHR_05196	ENOG4108IV0	ABC, transporter
H4CHR_05197	ENOG4105C0Z	ABC transporter
H4CHR_05198	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
H4CHR_05199	ENOG4105C32	Amino acid ABC transporter (Permease)
H4CHR_05201	ENOG4105Q56	cytochrome P450
H4CHR_05205	ENOG4105CHR	reductase
H4CHR_05206	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
H4CHR_05207	ENOG4105NI3	Protein of unknown function (DUF3237)
H4CHR_05210	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
H4CHR_05211	ENOG4105C32	Amino acid ABC transporter (Permease)
H4CHR_05212	ENOG4108IV0	ABC, transporter
H4CHR_05213	ENOG4105C0Z	ABC transporter
H4CHR_05214	ENOG4105DAB	fumarate reductase succinate dehydrogenase flavoprotein domain protein
H4CHR_05216	ENOG4105CHR	reductase
H4CHR_05224	ENOG4105Q56	cytochrome P450
H4CHR_05226	ENOG4105D44	asparaginase
H4CHR_05227	ENOG4108JQ6	ABC transporter
H4CHR_05228	ENOG4105DEF	Extracellular solute-binding protein, family 5
H4CHR_05230	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
H4CHR_05234	ENOG4108VAU	general secretion pathway protein G
H4CHR_05236	ENOG4105GVR	general secretion pathway protein D
H4CHR_05241	ENOG4107QHF	type ii secretion system protein e
H4CHR_05243	ENOG4108VAU	general secretion pathway protein G
H4CHR_05251	ENOG4105DDW	LysR family Transcriptional regulator
H4CHR_05254	ENOG4106RE7	Cytochrome
H4CHR_05255	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
H4CHR_05265	ENOG4108Z20	Acyl-transferase
H4CHR_05266	ENOG4105CD3	dihydroorotase
H4CHR_05267	ENOG4105CXT	aspartate transcarbamylase
H4CHR_05268	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
H4CHR_05269	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
H4CHR_05270	ENOG4108UJU	UPF0301 protein
H4CHR_05271	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
H4CHR_05273	ENOG4105C8Q	Methyl-accepting chemotaxis
H4CHR_05275	ENOG4105M3Z	response regulator
H4CHR_05276	ENOG4108UNF	response regulator
H4CHR_05278	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
H4CHR_05279	ENOG4105DC1	bifunctional purine biosynthesis protein purh
H4CHR_05281	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
H4CHR_05282	ENOG4105W39	Membrane
H4CHR_05283	ENOG4105C3G	gtp-binding protein
H4CHR_05284	ENOG4105QVC	MOSC domain-containing protein
H4CHR_05285	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
H4CHR_05288	ENOG4105E39	Enoyl-CoA hydratase
H4CHR_05299	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
H4CHR_05300	ENOG4108UMZ	Cdp-alcohol phosphatidyltransferase
H4CHR_05301	ENOG4105E8V	Alpha Beta Hydrolase Fold protein
H4CHR_05302	ENOG41077RS	Phosphatase
H4CHR_05305	ENOG4108HPI	phosphatidate Cytidylyltransferase
H4CHR_05306	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
H4CHR_05307	ENOG4105C9A	Phoh family
H4CHR_05308	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
H4CHR_05309	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
H4CHR_05314	ENOG4105DR5	peptidase
H4CHR_05315	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
H4CHR_05316	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
H4CHR_05317	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
H4CHR_05318	ENOG4108UJD	30S ribosomal protein S9
H4CHR_05319	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
H4CHR_05320	ENOG4105D6S	protein involved in catabolism of external DNA
H4CHR_05322	ENOG4105SYT	Methylenetetrahydrofolate reductase
H4CHR_05324	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
H4CHR_05325	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
H4CHR_05328	ENOG4105JN3	extra-cytoplasmic solute receptor family protein
H4CHR_05329	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
H4CHR_05331	ENOG4105CSH	Transporter
H4CHR_05335	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
H4CHR_05336	ENOG4105JPG	D-isomer specific 2-hydroxyacid dehydrogenase
H4CHR_05338	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
H4CHR_05339	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
H4CHR_05341	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
H4CHR_05344	ENOG4108IPT	Naphthoate synthase
H4CHR_05346	ENOG4107QX3	carboxylase
H4CHR_05347	ENOG4105CEY	Amp-dependent synthetase and ligase
H4CHR_05348	ENOG4105C1G	acyl-Coa dehydrogenase
H4CHR_05351	ENOG4107UB3	HAD-superfamily hydrolase subfamily IA variant 3
H4CHR_05352	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
H4CHR_05356	ENOG4105K5B	UPF0225 protein
H4CHR_05358	ENOG4105C1G	acyl-Coa dehydrogenase
H4CHR_05361	ENOG4105CHU	acetyl-coa acetyltransferase
H4CHR_05362	ENOG4105VS7	Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation (By similarity)
H4CHR_05363	ENOG41077A9	carbonic anhydrase
H4CHR_05364	ENOG4108Z6Z	Transcriptional regulator
H4CHR_05367	ENOG4105EI2	Pseudouridine synthase
H4CHR_05368	ENOG4105CHR	reductase
H4CHR_05371	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
H4CHR_05372	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
H4CHR_05373	ENOG4107QIB	glycyl-tRNA synthetase, alpha subunit
H4CHR_05374	ENOG4105HDK	L-asparaginase
H4CHR_05376	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
H4CHR_05377	ENOG4108JU5	Magnesium and cobalt efflux protein
H4CHR_05379	ENOG4105J0Q	Transcriptional regulator
H4CHR_05381	ENOG4105F87	Dehydratase
H4CHR_05382	ENOG4105MIR	Phenylalanine 4-monooxygenase
H4CHR_05384	ENOG4105CEY	Amp-dependent synthetase and ligase
H4CHR_05390	ENOG4105C5H	ABC transporter
H4CHR_05391	ENOG4107RZC	phospholipase d
H4CHR_05392	ENOG4105CHM	Aminotransferase
H4CHR_05394	ENOG4105T38	integral membrane protein
H4CHR_05395	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
H4CHR_05397	ENOG4108NIW	Leucine export protein LeuE
H4CHR_05398	ENOG4108TGY	Glutathione S-transferase
H4CHR_05399	ENOG4105JAB	phenazine biosynthesis protein, phzf family
H4CHR_05405	ENOG4105F4K	antigen 43
H4CHR_05407	ENOG4105VF7	tolerance protein
H4CHR_05410	ENOG4108V1U	phospholipid-binding protein
H4CHR_05413	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
H4CHR_05414	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
H4CHR_05415	ENOG4108IFH	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
H4CHR_05416	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
H4CHR_05417	ENOG4105C25	Primosomal protein n'
H4CHR_05420	ENOG4105RK9	auxin efflux carrier
H4CHR_05421	ENOG4105C4R	Atp-dependent dna helicase
H4CHR_05423	ENOG4105HDD	phospholipase
H4CHR_05425	ENOG4105DAB	fumarate reductase succinate dehydrogenase flavoprotein domain protein
H4CHR_05430	ENOG41073TP	transcriptional regulator
H4CHR_05442	ENOG4107NQ8	LysR family Transcriptional regulator
H4CHR_05450	ENOG4105JN3	extra-cytoplasmic solute receptor family protein
H4CHR_05453	ENOG4105CC9	acyl-Coa dehydrogenase
H4CHR_05454	ENOG4105C1G	acyl-Coa dehydrogenase
H4CHR_05455	ENOG4105CEY	Amp-dependent synthetase and ligase
H4CHR_05457	ENOG4105EA8	2-Nitropropane dioxygenase
H4CHR_05459	ENOG4105CGU	Enoyl-CoA hydratase
H4CHR_05460	ENOG4105CHR	reductase
H4CHR_05463	ENOG4105CGU	Enoyl-CoA hydratase
H4CHR_05469	ENOG4108WYP	Transcriptional regulator
H4CHR_05470	ENOG4108J8Z	aliphatic sulfonates family ABC transporter periplasmic ligand-binding protein
H4CHR_05471	ENOG4108IY8	ABC, transporter
H4CHR_05472	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
H4CHR_05483	ENOG4105DSP	amino acid AbC transporter
H4CHR_05484	ENOG4105EAD	ABC transporter
H4CHR_05487	ENOG4105CBG	Sulfatase
H4CHR_05488	ENOG4105DIA	mandelate racemase muconate lactonizing
H4CHR_05490	ENOG4105CZ6	Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine (By similarity)
H4CHR_05494	ENOG4105ES5	Histidine kinase
H4CHR_05496	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
H4CHR_05498	ENOG4107QR0	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
H4CHR_05499	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
H4CHR_05500	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
H4CHR_05501	ENOG4108VZM	50s ribosomal protein L10
H4CHR_05503	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
H4CHR_05504	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
H4CHR_05506	ENOG4105PM1	preprotein translocase subunit SecE
H4CHR_05508	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
H4CHR_05512	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
H4CHR_05513	ENOG4105DK0	Indole-3-glycerol phosphate synthase
H4CHR_05514	ENOG4107QYG	anthranilate phosphoribosyltransferase
H4CHR_05516	ENOG4105DDQ	anthranilate synthase
H4CHR_05520	ENOG4105DTD	Dehydrogenase
H4CHR_05521	ENOG4105CHR	reductase
H4CHR_05522	ENOG4105CEY	Amp-dependent synthetase and ligase
H4CHR_05523	ENOG4108IV0	ABC, transporter
H4CHR_05524	ENOG4105C0Z	ABC transporter
H4CHR_05525	ENOG4105C32	Amino acid ABC transporter (Permease)
H4CHR_05528	ENOG4105FUY	alpha subunit
H4CHR_05531	ENOG4105CHR	reductase
H4CHR_05532	ENOG4106IPI	cyclase, family
H4CHR_05535	ENOG4105CHU	acetyl-coa acetyltransferase
H4CHR_05536	ENOG4105CEY	Amp-dependent synthetase and ligase
H4CHR_05539	ENOG4105E3J	oxidoreductase
H4CHR_05545	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
H4CHR_05547	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
H4CHR_05553	ENOG4105EUR	Domain-Containing protein
H4CHR_05553	ENOG4105EUR	Domain-Containing protein
H4CHR_05553	ENOG4105EUR	Domain-Containing protein
H4CHR_05554	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
H4CHR_05562	ENOG4108ZF3	Phosphatase
H4CHR_05563	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
H4CHR_05567	ENOG4105EHI	Phosphonate ABC transporter, periplasmic
H4CHR_05568	ENOG4105EHI	Phosphonate ABC transporter, periplasmic
H4CHR_05569	ENOG4105BZU	Histidine kinase
H4CHR_05580	ENOG4105C75	arginyL-tRNA synthetase
H4CHR_05583	ENOG4105WI0	lipopolysaccharide transport periplasmic protein lptA
H4CHR_05584	ENOG4108IUZ	ABC transporter
H4CHR_05585	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
H4CHR_05586	ENOG4107RZC	phospholipase d
H4CHR_05588	ENOG4108YYC	ycei family
H4CHR_05589	ENOG4105DS1	cytochrome b561
H4CHR_05592	ENOG4105BZU	Histidine kinase
H4CHR_05594	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
H4CHR_05598	ENOG4105NVB	glycoside hydrolase, family 19
H4CHR_05601	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
H4CHR_05606	ENOG4108ZAI	phosphatidylglycerophosphatase a
H4CHR_05609	ENOG4105WH1	Two component transcriptional regulator luxr family
H4CHR_05610	ENOG4105BZU	Histidine kinase
H4CHR_05613	ENOG4108IMY	Transcriptional regulator
H4CHR_05614	ENOG4107W7X	Aldolase
H4CHR_05615	ENOG4105CH5	extracellular solute-binding protein, family 7
H4CHR_05619	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
H4CHR_05620	ENOG4106KXD	ATP-dependent carboxylate-amine ligase (By similarity)
H4CHR_05622	ENOG4105NWN	ApaG protein
H4CHR_05623	ENOG4105DJV	ribulose-phosphate 3-epimerase
H4CHR_05625	ENOG4105DQE	DNA ligase
H4CHR_05629	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
H4CHR_05633	ENOG4105ETE	Transcriptional regulator (LacI family
H4CHR_05641	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
H4CHR_05642	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
H4CHR_05647	ENOG4107QP3	malate synthase g
H4CHR_05659	ENOG4107R15	K00850 6-phosphofructokinase 1 EC 2.7.1.11
H4CHR_05661	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
H4CHR_05662	ENOG4105E7A	Glutamine amidotransferase
H4CHR_05666	ENOG4105D7Z	glutathione synthase
H4CHR_05667	ENOG4105DKK	Benzoate
H4CHR_05668	ENOG4105DFH	Transport of potassium into the cell (By similarity)
H4CHR_05670	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
H4CHR_05673	ENOG4105C8T	Leucyl-tRNA synthetase
H4CHR_05674	ENOG4105SG9	biopolymer transport protein, ExbD
H4CHR_05676	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
H4CHR_05677	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
H4CHR_05678	ENOG41090R7	Ferric uptake
H4CHR_05679	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
H4CHR_05680	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
H4CHR_05681	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
H4CHR_05682	ENOG4105C4R	Atp-dependent dna helicase
H4CHR_05683	ENOG4107QUT	magnesium and cobalt transport protein CorA
H4CHR_05684	ENOG4105CEY	Amp-dependent synthetase and ligase
H4CHR_05685	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
H4CHR_05686	ENOG4105W8H	transhydrogenase (subunit alpha
H4CHR_05687	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
H4CHR_05688	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
H4CHR_05691	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
H4CHR_05693	ENOG4105DEN	Luciferase family
H4CHR_05697	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
H4CHR_05698	ENOG4107WZ3	Transferase
H4CHR_05699	ENOG4105D3Q	Sugar transferase
H4CHR_05700	ENOG4105CGN	Glycosyl transferase (Group 1
H4CHR_05701	ENOG4108PQP	glycosyl transferase group 1
H4CHR_05704	ENOG4108MX3	Polysaccharide Biosynthesis Protein
H4CHR_05705	ENOG4108IAJ	Nad-dependent epimerase dehydratase
H4CHR_05706	ENOG4107QQG	Dehydrogenase
H4CHR_05710	ENOG4108UUM	single-stranded DNA-binding protein
H4CHR_05711	ENOG4105CMQ	Chloride channel
H4CHR_05713	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
H4CHR_05714	ENOG4105C29	acyl-CoA thioesterase
H4CHR_05720	ENOG4105MSY	salicylate hydroxylase
H4CHR_05723	ENOG4108KB2	LysR family Transcriptional regulator
H4CHR_05725	ENOG4105BZU	Histidine kinase
H4CHR_05727	ENOG4105ETX	regulatoR
H4CHR_05731	ENOG4105ERH	Fumarylacetoacetate hydrolase
H4CHR_05732	ENOG4105F1J	Homogentisate 1,2-dioxygenase
H4CHR_05734	ENOG4105E2Q	3-(3-hydroxy-phenyl)propionate hydroxylase
H4CHR_05741	ENOG4105SKN	orotidine 5''-phosphate decarboxylase
H4CHR_05743	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
H4CHR_05744	ENOG41072GX	Peptidase M22 Glycoprotease
H4CHR_05747	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
H4CHR_05748	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
H4CHR_05749	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
H4CHR_05750	ENOG4107QR8	Thioredoxin
H4CHR_05752	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
H4CHR_05754	ENOG4105C8V	SAICAR synthetase
H4CHR_05756	ENOG4105CA9	Pyruvate kinase
H4CHR_05757	ENOG4105BZA	Phosphoglycerate kinase
H4CHR_05758	ENOG4105F04	LysR family Transcriptional regulator
H4CHR_05761	ENOG4105E2Q	3-(3-hydroxy-phenyl)propionate hydroxylase
H4CHR_05765	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
H4CHR_05769	ENOG4105C79	DNA protecting protein DprA
H4CHR_05770	ENOG4108RPN	Protein smg homolog
H4CHR_05772	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
H4CHR_05773	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
H4CHR_05774	ENOG4105VIE	preprotein translocase, subunit YajC
H4CHR_05776	ENOG4108YXU	transcriptional regulator AsnC family
H4CHR_05777	ENOG4107SFI	Major Facilitator superfamily
H4CHR_05787	ENOG4105QG4	Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity)
H4CHR_05788	ENOG4105FB2	class II Aldolase
H4CHR_05789	ENOG4105G63	Type III effector Hrp-dependent
H4CHR_05790	ENOG4105ZXK	Dehydrogenase
H4CHR_05793	ENOG4105C1J	atp-dependent rna helicase
H4CHR_05794	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
H4CHR_05795	ENOG4105C0H	protease
H4CHR_05797	ENOG4108Z86	Glutamine amidotransferase
H4CHR_05799	ENOG4105C9U	ATP-dependent DNA helicase RecQ
H4CHR_05801	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
H4CHR_05807	ENOG4105DHQ	Histidine kinase
H4CHR_05810	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
H4CHR_05811	ENOG4108004	Modulates RecA activity (By similarity)
H4CHR_05812	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
H4CHR_05813	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
H4CHR_05814	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
H4CHR_05815	ENOG4108ZCF	integral membrane protein
H4CHR_05816	ENOG4108ZF3	Phosphatase
H4CHR_05818	ENOG4105F8J	Adenylate Guanylate cyclase
H4CHR_05820	ENOG4105KHS	type IV fimbrial pilin protein
H4CHR_05828	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
H4CHR_05829	ENOG4105ERG	peptidase m48, ste24p
H4CHR_05830	ENOG41086DT	Membrane protein of unknown function
H4CHR_05832	ENOG4108ZCF	integral membrane protein
H4CHR_05836	ENOG4108VWS	Yaeq family
H4CHR_05837	ENOG4107QTF	adenylosuccinate lyase
H4CHR_05839	ENOG4108M3P	Membrane
H4CHR_05840	ENOG4108U78	Glutathione S-transferase
H4CHR_05843	ENOG4108KPJ	rna polymerase sigma factor
H4CHR_05844	ENOG4105K6T	rare lipoprotein A
H4CHR_05845	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
H4CHR_05848	ENOG4105BZU	Histidine kinase
H4CHR_05849	ENOG4108ZXC	Two component transcriptional regulator, luxr family
H4CHR_05855	ENOG4108YXU	transcriptional regulator AsnC family
H4CHR_05856	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
H4CHR_05857	ENOG4108RZE	Tetr family transcriptional regulator
H4CHR_05858	ENOG4105H37	Glyoxalase Bleomycin resistance protein (Dioxygenase
H4CHR_05867	ENOG4105CEV	competence damage-inducible protein
H4CHR_05868	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
H4CHR_05871	ENOG4107GJV	short-chain dehydrogenase reductase
H4CHR_05872	ENOG4107JEE	Short-chain dehydrogenase reductase Sdr
H4CHR_05873	ENOG4108YZY	peptidylprolyl cis-trans isomerase
H4CHR_05876	ENOG4105EUB	pirin domain protein
H4CHR_05880	ENOG4105E2Q	3-(3-hydroxy-phenyl)propionate hydroxylase
H4CHR_05882	ENOG4105ERH	Fumarylacetoacetate hydrolase
H4CHR_05883	ENOG4105CPC	Aldo Keto reductase
H4CHR_05887	ENOG4105BZ9	Cytochrome C oxidase, subunit I
H4CHR_05888	ENOG4105CV4	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
H4CHR_05890	ENOG4108Q1J	Extracellular solute-binding protein, family 3
H4CHR_05891	ENOG4105DZG	Dehydrogenase
H4CHR_05892	ENOG4105MFQ	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP) (By similarity)
H4CHR_05896	ENOG4107S2Z	UPF0761 membrane protein
H4CHR_05898	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
H4CHR_05911	ENOG4105EQ1	Transcriptional regulator
H4CHR_05912	ENOG4105CHJ	isochorismatase hydrolase
H4CHR_05913	ENOG4105EFZ	amidohydrolase
H4CHR_05918	ENOG4105EAM	Na Pi-cotransporter
H4CHR_05919	ENOG4105ETT	transcriptional Regulator, LysR family
H4CHR_05921	ENOG4105DAA	L-lactate
H4CHR_05922	ENOG4105CPN	adenine deaminase
H4CHR_05923	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
H4CHR_05927	ENOG4107TSX	ABC branched chain amino acid family transporter periplasmic ligand binding protein
H4CHR_05928	ENOG4105FAE	von Willebrand factor, type A
H4CHR_05930	ENOG4105DCY	Is an aliphatic amidase with a restricted substrate specificity, as it only hydrolyzes formamide (By similarity)
H4CHR_05931	ENOG4108IV0	ABC, transporter
H4CHR_05932	ENOG4105C0Z	ABC transporter
H4CHR_05933	ENOG4105C32	Amino acid ABC transporter (Permease)
H4CHR_05934	ENOG4105C32	Amino acid ABC transporter (Permease)
H4CHR_05936	ENOG4108WUH	Transcriptional regulator, TetR family
H4CHR_05940	ENOG4105D3Z	quinone oxidoreductase, yhdh yhfp family
H4CHR_05942	ENOG4105CR8	Transcriptional regulator
H4CHR_05947	ENOG4105DND	Transcriptional regulator
H4CHR_05950	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
H4CHR_05953	ENOG4105C32	Amino acid ABC transporter (Permease)
H4CHR_05954	ENOG4108IUZ	ABC transporter
H4CHR_05955	ENOG4108IV0	ABC, transporter
H4CHR_05956	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
H4CHR_05959	ENOG4105WEF	catalase
H4CHR_05960	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
H4CHR_05962	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
H4CHR_05964	ENOG4105BZU	Histidine kinase
H4CHR_05973	ENOG4108IAJ	Nad-dependent epimerase dehydratase
H4CHR_05987	ENOG4105C9U	ATP-dependent DNA helicase RecQ
H4CHR_05991	ENOG4105HSS	phospholipase C
H4CHR_06006	ENOG4105CGF	Aromatic amino acid aminotransferase
H4CHR_06007	ENOG41061MV	Arylsulfatase
H4CHR_06009	ENOG4105DUM	transcriptional regulator, lysR family
H4CHR_06010	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
H4CHR_06012	ENOG4105CNV	Aldolase
H4CHR_06014	ENOG4105ERH	Fumarylacetoacetate hydrolase
H4CHR_06016	ENOG4105KME	endoribonuclease L-psp
H4CHR_06018	ENOG4107XC4	flavin reductase domain protein, FMN-binding
H4CHR_06027	ENOG4105C1G	acyl-Coa dehydrogenase
H4CHR_06028	ENOG4105CEY	Amp-dependent synthetase and ligase
H4CHR_06033	ENOG41067TZ	transcriptional regulator, MarR family
H4CHR_06034	ENOG4105CQB	FAD linked oxidase domain protein
H4CHR_06035	ENOG4105DRR	Transcriptional regulator, GntR family
H4CHR_06036	ENOG4105C5R	Aminotransferase
H4CHR_06040	ENOG4108VX5	3-methyladenine DNA glycosylase
H4CHR_06047	ENOG4105DZR	Type I site-specific deoxyribonuclease
H4CHR_06051	ENOG4105FDP	GntR family transcriptional regulator
H4CHR_06052	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
H4CHR_06053	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
H4CHR_06056	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
H4CHR_06057	ENOG4105CV1	Transketolase (EC 2.2.1.1)
H4CHR_06058	ENOG4105X3E	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
H4CHR_06059	ENOG4108S0S	Nucleotidyl transferase
H4CHR_06064	ENOG4107RAQ	aminopeptidase
H4CHR_06072	ENOG4105C6K	Malic enzyme
H4CHR_06076	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
H4CHR_06077	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
H4CHR_06078	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
H4CHR_06079	ENOG4105EHM	Aminoglycoside phosphotransferase
H4CHR_06080	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
H4CHR_06083	ENOG4105DXI	Major Facilitator superfamily
H4CHR_06087	ENOG4105EYW	Ion transport protein
H4CHR_06088	ENOG4105DWV	Homoserine O-trans-acetylase
H4CHR_06089	ENOG4105DWV	Homoserine O-trans-acetylase
H4CHR_06091	ENOG4105VFU	Rna-binding protein
H4CHR_06092	ENOG4107FW0	short-chain dehydrogenase reductase
H4CHR_06094	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
H4CHR_06095	ENOG4105C2X	Arabinose 5-phosphate isomerase
H4CHR_06099	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
H4CHR_06100	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
H4CHR_06101	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
H4CHR_06102	ENOG4105X5M	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
H4P1_00001	ENOG4107SKI	cobyrinic Acid a,c-diamide synthase
H4P1_00004	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
H4P1_00018	ENOG4105JAB	phenazine biosynthesis protein, phzf family
H4P1_00035	ENOG4105KDM	Diguanylate cyclase with gaf sensor
H4P1_00041	ENOG4105DQE	DNA ligase
H4P1_00043	ENOG4105D9P	serine threonine protein kinase
H4P1_00058	ENOG4105F9F	transposase
H4P1_00076	ENOG4108KQ5	Integrase catalytic subunit
H4P1_00083	ENOG4108C33	Resolvase
H4P1_00087	ENOG4105GYP	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline (By similarity)
H4P2_00005	ENOG4106IJN	integrase catalytic domain-containing protein
H4P2_00029	ENOG4105E5H	Transposase
H4P2_00046	ENOG4105W5Q	DNA repair protein (RadC
H4P2_00065	ENOG4106D0Q	Type IV secretion system protein VirB2
H4P2_00073	ENOG4105CMA	conjugation trbi family protein
H4P2_00085	ENOG4105EFZ	amidohydrolase
H4P2_00111	ENOG4105VT3	DNA binding domain protein, excisionase family