locus-tag	class	description
Vpar_0001	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
Vpar_0002	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
Vpar_0004	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
Vpar_0007	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
Vpar_0008	ENOG4108IQI	permease
Vpar_0009	ENOG4105K8R	UPF0145 protein
Vpar_0011	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
Vpar_0017	ENOG4106WTF	Glycosyl transferase, family 2
Vpar_0021	ENOG4105D3Q	Sugar transferase
Vpar_0022	ENOG4108TGC	Acyltransferase
Vpar_0023	ENOG4105D5D	udp-galactopyranose mutase
Vpar_0027	ENOG4108KMV	Glycosyl transferase (Group 1
Vpar_0028	ENOG4107BJW	polysaccharide deacetylase
Vpar_0029	ENOG4105KPE	licD family
Vpar_0030	ENOG4107XDJ	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
Vpar_0032	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
Vpar_0041	ENOG4105ZU5	s-layer protein
Vpar_0055	ENOG4105EUB	pirin domain protein
Vpar_0057	ENOG4105D0M	Protease HtpX homolog
Vpar_0061	ENOG4105D05	Receptor
Vpar_0063	ENOG4105EHG	Permease protein
Vpar_0065	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
Vpar_0067	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
Vpar_0068	ENOG4105EHG	Permease protein
Vpar_0069	ENOG4105E0A	ABC, transporter
Vpar_0072	ENOG4105CTK	cobaltochelatase, cobn subunit
Vpar_0074	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
Vpar_0075	ENOG4105CHM	Aminotransferase
Vpar_0076	ENOG4105WAB	arsR family transcriptional regulator
Vpar_0077	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
Vpar_0078	ENOG41090P5	ferredoxin-like protein
Vpar_0079	ENOG4105BZJ	Electron transfer flavoprotein
Vpar_0080	ENOG4105C10	Electron transfer flavoprotein
Vpar_0081	ENOG4105EMU	Dehydrogenase
Vpar_0085	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
Vpar_0086	ENOG4107RRN	ABC transporter substrate-binding protein
Vpar_0087	ENOG4105C3U	ABC transporter
Vpar_0088	ENOG4108JQ7	(ABC) transporter
Vpar_0094	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
Vpar_0095	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
Vpar_0096	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
Vpar_0097	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
Vpar_0098	ENOG4105RNB	
Vpar_0099	ENOG4108ESE	uses NADH to detoxify nitric oxide (NO), protecting several 4Fe-4S NO-sensitive enzymes. Has at least 2 reductase partners, only one of which (NorW, flavorubredoxin reductase) has been identified. NO probably binds to the di-iron center
Vpar_0100	ENOG4105QZY	s-layer domain protein
Vpar_0105	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
Vpar_0106	ENOG4105CNN	ABC, transporter
Vpar_0107	ENOG4105C2J	ABC transporter
Vpar_0108	ENOG4105MRB	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity)
Vpar_0109	ENOG4108RVA	ribokinase
Vpar_0116	ENOG4105CVR	type I restriction-modification system
Vpar_0118	ENOG4105DZR	Type I site-specific deoxyribonuclease
Vpar_0119	ENOG4108JJB	ABC transporter
Vpar_0120	ENOG4108JJB	ABC transporter
Vpar_0123	ENOG4108W76	histidinol phosphate phosphatase hisj family
Vpar_0125	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
Vpar_0126	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
Vpar_0128	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
Vpar_0129	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
Vpar_0130	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
Vpar_0133	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
Vpar_0139	ENOG4105CSD	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
Vpar_0141	ENOG4105C6T	cysteine synthase
Vpar_0142	ENOG4105D7W	serine acetyltransferase
Vpar_0143	ENOG4108RMU	ferritin dps family protein
Vpar_0145	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
Vpar_0147	ENOG41087XH	Protein of unknown function (DUF328)
Vpar_0148	ENOG4107QW8	radical SAM domain protein
Vpar_0149	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
Vpar_0150	ENOG4108R66	Conserved Protein
Vpar_0151	ENOG4108UZ3	Transporter
Vpar_0158	ENOG4105CRQ	synthase (Component I)
Vpar_0159	ENOG4105DDQ	anthranilate synthase
Vpar_0160	ENOG4108I0Q	anthranilate phosphoribosyltransferase
Vpar_0161	ENOG4105DK0	Indole-3-glycerol phosphate synthase
Vpar_0162	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
Vpar_0163	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
Vpar_0166	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
Vpar_0171	ENOG4105BZ1	(ABC) transporter
Vpar_0172	ENOG4105EZY	Pyrroloquinoline quinone biosynthesis protein E
Vpar_0174	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
Vpar_0176	ENOG4107R0W	ABC transporter
Vpar_0178	ENOG410667J	hydrolase
Vpar_0180	ENOG4105CV8	reductase
Vpar_0181	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
Vpar_0197	ENOG4105EHG	Permease protein
Vpar_0198	ENOG4105E0A	ABC, transporter
Vpar_0199	ENOG4105CC5	ABC transporter
Vpar_0200	ENOG4107RPQ	ABC transporter
Vpar_0201	ENOG4105DIK	(ABC) transporter
Vpar_0202	ENOG4107SIG	periplasmic solute binding protein
Vpar_0208	ENOG4105C5Q	Transcriptional regulator
Vpar_0209	ENOG4105CJG	carbon-monoxide dehydrogenase catalytic subunit
Vpar_0210	ENOG4105IGJ	Zn-dependent Hydrolase of the beta-lactamase fold protein
Vpar_0213	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
Vpar_0214	ENOG4107VRP	DNA repair exonuclease
Vpar_0215	ENOG4106D4I	domain protein
Vpar_0216	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
Vpar_0217	ENOG4107TTW	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
Vpar_0218	ENOG4105C1Q	protoporphyrinogen oxidase
Vpar_0219	ENOG4107JTW	chlorite dismutase
Vpar_0220	ENOG4105DQQ	Major facilitator superfamily MFS_1
Vpar_0221	ENOG4107V6Q	Cyclic nucleotide-binding domain
Vpar_0223	ENOG4108IUE	nitrate reductase beta subunit
Vpar_0224	ENOG4105R3A	Nitrate reductase
Vpar_0227	ENOG4105ZU5	s-layer protein
Vpar_0229	ENOG4105C6X	Major Facilitator
Vpar_0230	ENOG4105DND	Transcriptional regulator
Vpar_0232	ENOG4105HMI	Membrane
Vpar_0233	ENOG4108V2W	Carbonate dehydratase
Vpar_0235	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
Vpar_0236	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
Vpar_0238	ENOG4105FAV	ABC, transporter
Vpar_0239	ENOG4105FDK	ABC transporter
Vpar_0240	ENOG4105DSE	periplasmic solute binding protein
Vpar_0249	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
Vpar_0250	ENOG4105C5I	Dehydrogenase
Vpar_0252	ENOG4105C59	p-type ATPase
Vpar_0253	ENOG4105F1A	Pyruvate formate-lyase
Vpar_0254	ENOG4105C6N	Formate acetyltransferase
Vpar_0259	ENOG4108UMI	ABC transporter, permease
Vpar_0260	ENOG4105D01	(LipO)protein
Vpar_0263	ENOG4107QPK	)-transporter
Vpar_0266	ENOG4105C28	cystathionine
Vpar_0267	ENOG4105C87	Aminotransferase class I and II
Vpar_0268	ENOG4105CVG	Homoserine O-transsuccinylase
Vpar_0273	ENOG4108PJD	permease
Vpar_0274	ENOG4105CKI	cobalamin synthesis protein
Vpar_0275	ENOG4105CIN	aminoacyl-histidine dipeptidase
Vpar_0276	ENOG4105DAP	Nicotinate phosphoribosyltransferase
Vpar_0278	ENOG4107RB3	L-asparaginase
Vpar_0280	ENOG4105D64	Mechanosensitive ion channel
Vpar_0281	ENOG4105DZ1	carboxypeptidase
Vpar_0283	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
Vpar_0285	ENOG4108XHQ	(2Fe-2S)-binding domain protein
Vpar_0286	ENOG4105C7W	Xanthine dehydrogenase
Vpar_0290	ENOG4107P0T	Selenium-dependent molybdenum hydroxylase system protein, YqeB family
Vpar_0292	ENOG4105C8B	TIGR00159 family
Vpar_0293	ENOG4107U5W	ybbr family
Vpar_0294	ENOG4105DZ0	fad dependent oxidoreductase
Vpar_0295	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
Vpar_0299	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
Vpar_0300	ENOG4105C31	Tryptophanyl-tRNA synthetase
Vpar_0302	ENOG4105E89	ABC transporter
Vpar_0303	ENOG4105E5Q	amino acid AbC transporter
Vpar_0304	ENOG4105CDA	abc transporter atp-binding protein
Vpar_0307	ENOG4107YCR	Transcriptional regulator, ARSR family
Vpar_0309	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
Vpar_0310	ENOG4105E0C	molybdate abc transporter
Vpar_0311	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
Vpar_0316	ENOG4108RAC	Rubrerythrin
Vpar_0318	ENOG4105D4F	Synthesizes selenophosphate from selenide and ATP (By similarity)
Vpar_0321	ENOG4108RCM	Nitroreductase
Vpar_0322	ENOG4107BMA	Transglycosylase associated protein
Vpar_0324	ENOG4105C3G	gtp-binding protein
Vpar_0325	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
Vpar_0326	ENOG4108W0P	ABC transporter
Vpar_0327	ENOG4105EHG	Permease protein
Vpar_0328	ENOG4105S10	periplasmic binding protein
Vpar_0331	ENOG4105CHM	Aminotransferase
Vpar_0335	ENOG4105C2C	drug resistance transporter, Bcr CflA
Vpar_0336	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
Vpar_0337	ENOG4108UUM	single-stranded DNA-binding protein
Vpar_0338	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
Vpar_0341	ENOG4105CGC	Nitrogenase cofactor biosynthesis protein NifB
Vpar_0346	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
Vpar_0347	ENOG4105CNI	cell division protein FtsW
Vpar_0350	ENOG4105DI5	UPF0365 protein
Vpar_0356	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
Vpar_0357	ENOG4105EPD	Oligopeptide transporter, Opt family
Vpar_0359	ENOG4108J5H	Homocysteine s-methyltransferase
Vpar_0360	ENOG4105CNW	domain protein
Vpar_0361	ENOG4108JIU	phosphoribosylformylglycinamidine synthase ii
Vpar_0362	ENOG4108M0I	Transcriptional regulator
Vpar_0363	ENOG4108UPS	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis (By similarity)
Vpar_0369	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
Vpar_0370	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
Vpar_0372	ENOG4105C12	Phosphoribosylglycinamide synthetase
Vpar_0373	ENOG4105E4F	Isochorismate synthase
Vpar_0374	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
Vpar_0375	ENOG4107J5P	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity)
Vpar_0376	ENOG4108IPT	Naphthoate synthase
Vpar_0377	ENOG4105CEY	Amp-dependent synthetase and ligase
Vpar_0378	ENOG4105DTQ	mandelate racemase muconate lactonizing
Vpar_0387	ENOG4105CXY	transporter
Vpar_0390	ENOG4105CQP	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
Vpar_0391	ENOG4107BJW	polysaccharide deacetylase
Vpar_0392	ENOG4108HQ0	Exopolysaccharide biosynthesis protein
Vpar_0394	ENOG4105XA0	heptosyltransferase ii
Vpar_0396	ENOG4107QSA	Oxaloacetate decarboxylase
Vpar_0399	ENOG4105C0H	protease
Vpar_0404	ENOG4107XPQ	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
Vpar_0405	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
Vpar_0406	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
Vpar_0410	ENOG4105D01	(LipO)protein
Vpar_0411	ENOG4105EIS	1,4-dihydroxy-2-naphthoate octaprenyltransferase
Vpar_0414	ENOG4105KME	endoribonuclease L-psp
Vpar_0415	ENOG4105CEM	UPF0597 protein
Vpar_0416	ENOG4105EU0	Major facilitator Superfamily
Vpar_0417	ENOG4108Z6B	deaminase
Vpar_0418	ENOG4105EN6	Membrane
Vpar_0421	ENOG4105F0I	Aminotransferase
Vpar_0422	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
Vpar_0423	ENOG4108UMI	ABC transporter, permease
Vpar_0424	ENOG4105KGF	protein, YerC YecD
Vpar_0426	ENOG4105CBZ	Short-chain dehydrogenase reductase Sdr
Vpar_0430	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
Vpar_0433	ENOG4107RID	5-oxoprolinase (ATP-hydrolyzing)
Vpar_0434	ENOG4105DGU	Histone deacetylase
Vpar_0435	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
Vpar_0436	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
Vpar_0438	ENOG4105FDS	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
Vpar_0439	ENOG4105C6K	Malic enzyme
Vpar_0442	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
Vpar_0448	ENOG4107QMH	DNA methylase
Vpar_0454	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
Vpar_0456	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
Vpar_0459	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
Vpar_0460	ENOG4105E7W	lamb ycsf family protein
Vpar_0461	ENOG4105C5A	transporter
Vpar_0462	ENOG4105P4J	Allophanate hydrolase, subunit 1
Vpar_0465	ENOG4105UQX	Mate efflux family protein
Vpar_0467	ENOG4108ZG0	Ompa motb domain protein
Vpar_0468	ENOG4105C02	permease
Vpar_0471	ENOG4108FUT	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) (By similarity)
Vpar_0472	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
Vpar_0474	ENOG4107BJW	polysaccharide deacetylase
Vpar_0475	ENOG4105EPU	Molybdenum cofactor synthesis domain protein
Vpar_0477	ENOG4105C4M	(Ubiquinol oxidase) subunit I
Vpar_0478	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
Vpar_0479	ENOG4108JJ9	ABC, transporter
Vpar_0484	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
Vpar_0485	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
Vpar_0487	ENOG4108JQ7	(ABC) transporter
Vpar_0490	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
Vpar_0492	ENOG4105C5H	ABC transporter
Vpar_0493	ENOG4105EUJ	GTP cyclohydrolase i
Vpar_0494	ENOG4105EEI	dihydropteroate synthase
Vpar_0496	ENOG4105EUJ	GTP cyclohydrolase i
Vpar_0498	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
Vpar_0500	ENOG41060GV	RNA binding s1 domain protein
Vpar_0502	ENOG4107THF	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
Vpar_0503	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
Vpar_0504	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
Vpar_0507	ENOG4105CGM	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
Vpar_0508	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
Vpar_0509	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
Vpar_0510	ENOG4105CRK	lysyL-tRNA synthetase
Vpar_0511	ENOG4105C7N	Xanthine uracil vitamin C permease
Vpar_0512	ENOG4107QUY	Guanine deaminase
Vpar_0515	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
Vpar_0516	ENOG4105CBT	Fructose-1,6-bisphosphatase
Vpar_0517	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
Vpar_0523	ENOG4105DHJ	ABC, transporter
Vpar_0531	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
Vpar_0532	ENOG4105D1S	lipid A biosynthesis
Vpar_0533	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
Vpar_0534	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
Vpar_0535	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
Vpar_0538	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
Vpar_0539	ENOG4105BZ1	(ABC) transporter
Vpar_0540	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
Vpar_0541	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
Vpar_0542	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
Vpar_0543	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
Vpar_0544	ENOG4105C2X	Arabinose 5-phosphate isomerase
Vpar_0545	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
Vpar_0548	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
Vpar_0549	ENOG4108IUZ	ABC transporter
Vpar_0551	ENOG4108R0D	protein with myosin-like
Vpar_0553	ENOG4108JYZ	YitT family
Vpar_0554	ENOG4105C3F	Signal peptidase i
Vpar_0555	ENOG4105ZU5	s-layer protein
Vpar_0556	ENOG4105ZU5	s-layer protein
Vpar_0557	ENOG4105ZU5	s-layer protein
Vpar_0559	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
Vpar_0561	ENOG4105CIE	May be required for sporulation (By similarity)
Vpar_0563	ENOG4105CXT	aspartate transcarbamylase
Vpar_0564	ENOG4105CD3	dihydroorotase
Vpar_0567	ENOG4105DF0	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) (By similarity)
Vpar_0568	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
Vpar_0569	ENOG4108KSA	LysR family transcriptional regulator
Vpar_0571	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
Vpar_0572	ENOG4105C59	p-type ATPase
Vpar_0574	ENOG4107QN2	dihydrolipoyl dehydrogenase
Vpar_0575	ENOG4105VBN	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein (By similarity)
Vpar_0577	ENOG4105K5M	30s ribosomal protein S16
Vpar_0580	ENOG4107Z8R	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
Vpar_0581	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
Vpar_0588	ENOG4108WTY	tRNA (Guanine-N(1)-)-methyltransferase
Vpar_0589	ENOG4105CDY	transcriptional regulatory protein
Vpar_0590	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
Vpar_0591	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
Vpar_0592	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
Vpar_0593	ENOG4105JFG	SpoIID LytB domain protein
Vpar_0595	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
Vpar_0596	ENOG4105VIE	preprotein translocase, subunit YajC
Vpar_0598	ENOG4105C3D	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
Vpar_0599	ENOG4107SBW	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
Vpar_0600	ENOG4105CZM	Major Facilitator
Vpar_0601	ENOG4105X1Q	TOBE domain protein
Vpar_0603	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
Vpar_0604	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
Vpar_0605	ENOG41069ER	domain protein
Vpar_0606	ENOG4105DFT	pur operon repressor
Vpar_0607	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
Vpar_0609	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
Vpar_0610	ENOG4105CXN	decarboxylase
Vpar_0611	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
Vpar_0612	ENOG4107QMP	dna polymerase iii subunits gamma and tau
Vpar_0613	ENOG4105MA4	psp1 domain protein
Vpar_0614	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
Vpar_0615	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
Vpar_0616	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
Vpar_0617	ENOG4105F8V	Hydrolase, tatD family
Vpar_0620	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
Vpar_0621	ENOG41069ER	domain protein
Vpar_0622	ENOG4105E0X	reductase
Vpar_0624	ENOG4107R11	Transcriptional regulator
Vpar_0625	ENOG4105HVR	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step (By similarity)
Vpar_0626	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
Vpar_0627	ENOG4105D6U	Sodium Glutamate Symporter
Vpar_0628	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
Vpar_0629	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
Vpar_0630	ENOG4105C1J	atp-dependent rna helicase
Vpar_0632	ENOG4105CE1	Ferrous iron transport protein b
Vpar_0640	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
Vpar_0650	ENOG4105VKD	bioY protein
Vpar_0652	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
Vpar_0654	ENOG4108Z66	YbaK ebsC protein
Vpar_0655	ENOG4108B1Q	Ribonuclease
Vpar_0656	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
Vpar_0658	ENOG4107QP8	phosphohexose isomerase
Vpar_0659	ENOG4105CMR	udp-glucose 4-epimerase
Vpar_0661	ENOG4105E4G	Type IV pilus
Vpar_0662	ENOG4105C5H	ABC transporter
Vpar_0663	ENOG4105CP9	extracellular ligand-binding receptor
Vpar_0664	ENOG4105C32	Amino acid ABC transporter (Permease)
Vpar_0665	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
Vpar_0666	ENOG4105C0Z	ABC transporter
Vpar_0667	ENOG4108IV0	ABC, transporter
Vpar_0670	ENOG4105D75	Capsular exopolysaccharide family
Vpar_0672	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
Vpar_0674	ENOG4105KPE	licD family
Vpar_0675	ENOG4107XDJ	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
Vpar_0676	ENOG4105C5E	polysaccharide biosynthesis protein
Vpar_0677	ENOG4108PQP	glycosyl transferase group 1
Vpar_0686	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
Vpar_0687	ENOG4108RDD	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity)
Vpar_0691	ENOG4105VCQ	rubredoxin
Vpar_0693	ENOG41067VY	50S ribosomal protein L32
Vpar_0694	ENOG4108VVV	Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism (By similarity)
Vpar_0696	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
Vpar_0697	ENOG4105EA8	2-Nitropropane dioxygenase
Vpar_0698	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
Vpar_0699	ENOG4105CHR	reductase
Vpar_0700	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
Vpar_0701	ENOG4105EA8	2-Nitropropane dioxygenase
Vpar_0702	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
Vpar_0703	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
Vpar_0704	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
Vpar_0705	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
Vpar_0706	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
Vpar_0708	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
Vpar_0709	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
Vpar_0710	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
Vpar_0711	ENOG4107QMU	Mate efflux family protein
Vpar_0712	ENOG4108ZCF	integral membrane protein
Vpar_0713	ENOG4108ZCF	integral membrane protein
Vpar_0714	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
Vpar_0719	ENOG4105D05	Receptor
Vpar_0721	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
Vpar_0744	ENOG4105ERH	Fumarylacetoacetate hydrolase
Vpar_0745	ENOG4105CM2	brancheD-chain amino acid aminotransferase
Vpar_0748	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
Vpar_0750	ENOG4107QPK	)-transporter
Vpar_0751	ENOG4105DFM	M18 family aminopeptidase
Vpar_0752	ENOG4108JIJ	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity)
Vpar_0753	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
Vpar_0755	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
Vpar_0756	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
Vpar_0757	ENOG4105CUI	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity)
Vpar_0758	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
Vpar_0759	ENOG4105XA0	heptosyltransferase ii
Vpar_0761	ENOG4107S1V	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
Vpar_0762	ENOG4105DFM	M18 family aminopeptidase
Vpar_0766	ENOG4105C7J	ABC transporter, permease
Vpar_0767	ENOG4108JJB	ABC transporter
Vpar_0768	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
Vpar_0769	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
Vpar_0770	ENOG4107Z0P	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
Vpar_0771	ENOG4106R49	Methyltransferase
Vpar_0774	ENOG4105C7N	Xanthine uracil vitamin C permease
Vpar_0779	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
Vpar_0780	ENOG4107SC1	transglycosylase
Vpar_0782	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
Vpar_0783	ENOG4105CHV	Transcription elongation factor NusA
Vpar_0785	ENOG4105VHM	ribosomal protein
Vpar_0786	ENOG4107EEM	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
Vpar_0787	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
Vpar_0788	ENOG4105SFS	phosphoesterase RecJ domain protein
Vpar_0790	ENOG4105DTN	riboflavin biosynthesis protein ribF
Vpar_0792	ENOG4105C7H	Helicase, RecD TraA family
Vpar_0793	ENOG4105MJ2	Competence protein
Vpar_0794	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
Vpar_0795	ENOG4105EAB	amino acid AbC transporter
Vpar_0796	ENOG4105E5Q	amino acid AbC transporter
Vpar_0798	ENOG4105VEQ	Cold shock protein
Vpar_0800	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
Vpar_0805	ENOG4108HHA	Transketolase
Vpar_0806	ENOG4108IUS	Transketolase
Vpar_0807	ENOG4105CAK	Cell division ATP-binding protein ftsE
Vpar_0808	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
Vpar_0809	ENOG4105DR5	peptidase
Vpar_0811	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
Vpar_0813	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
Vpar_0814	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
Vpar_0815	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
Vpar_0816	ENOG4108WF2	Metal Dependent Phosphohydrolase
Vpar_0819	ENOG4105QNR	S1 RNA binding domain protein
Vpar_0820	ENOG4105C1A	potassium transporter peripheral membrane
Vpar_0821	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
Vpar_0822	ENOG4107VMB	Beta-lactamase domain protein
Vpar_0823	ENOG4105EWC	Purine nucleoside phosphorylase
Vpar_0825	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
Vpar_0826	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
Vpar_0827	ENOG4105FE9	pseudouridine synthase
Vpar_0828	ENOG4105CBX	hi0933 family
Vpar_0829	ENOG4105CAT	Cytidine monophosphate kinase
Vpar_0831	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
Vpar_0833	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
Vpar_0834	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
Vpar_0835	ENOG4106H78	methyltransferase
Vpar_0836	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
Vpar_0838	ENOG4105F23	Fibronectin-binding protein
Vpar_0839	ENOG4105DSJ	YicC domain protein
Vpar_0840	ENOG4105KC4	UPF0296 protein
Vpar_0841	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
Vpar_0842	ENOG41084KE	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
Vpar_0843	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
Vpar_0844	ENOG4105CHH	sulfate transporter
Vpar_0845	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
Vpar_0846	ENOG4105C25	Primosomal protein n'
Vpar_0847	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
Vpar_0848	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
Vpar_0851	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
Vpar_0852	ENOG4108ZF3	Phosphatase
Vpar_0853	ENOG4105D9P	serine threonine protein kinase
Vpar_0854	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
Vpar_0855	ENOG4105DJV	ribulose-phosphate 3-epimerase
Vpar_0856	ENOG4105CE9	30S ribosomal protein S2
Vpar_0857	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
Vpar_0858	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
Vpar_0859	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
Vpar_0862	ENOG4105KNE	Phosphatidate cytidylyltransferase
Vpar_0863	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
Vpar_0864	ENOG4105DZP	Membrane-associated zinc metalloprotease
Vpar_0865	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
Vpar_0866	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
Vpar_0867	ENOG4105DCG	PHP domain protein
Vpar_0869	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
Vpar_0871	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
Vpar_0872	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
Vpar_0873	ENOG4107YX5	Pfam:DUF548
Vpar_0875	ENOG4105CXI	aluminum resistance protein
Vpar_0876	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
Vpar_0877	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
Vpar_0878	ENOG4105CSA	Coproporphyrinogen iii oxidase
Vpar_0881	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
Vpar_0882	ENOG4105CFG	Acts as a chaperone (By similarity)
Vpar_0883	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
Vpar_0884	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
Vpar_0885	ENOG4107TVK	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
Vpar_0886	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
Vpar_0887	ENOG4107YU2	histidine triad (hIT) protein
Vpar_0889	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
Vpar_0892	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
Vpar_0893	ENOG4105BZ1	(ABC) transporter
Vpar_0894	ENOG4105BZ1	(ABC) transporter
Vpar_0895	ENOG4108RWN	rrna methyltransferase
Vpar_0896	ENOG410901P	UPF0249 protein
Vpar_0898	ENOG41090I5	UPF0735 ACT domain-containing protein
Vpar_0899	ENOG4105D6E	homoserine dehydrogenase
Vpar_0900	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
Vpar_0901	ENOG4105D0M	Protease HtpX homolog
Vpar_0902	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
Vpar_0905	ENOG4108YZT	Adenosylcobinamide kinase
Vpar_0906	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
Vpar_0907	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
Vpar_0908	ENOG4107XPA	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
Vpar_0909	ENOG4105JZC	GHMP kinase
Vpar_0910	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
Vpar_0911	ENOG4105CVJ	phosphoglycerate mutase
Vpar_0913	ENOG4105DC7	peptidase M24
Vpar_0914	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
Vpar_0917	ENOG4105M7K	Involved in the transcription termination process (By similarity)
Vpar_0918	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
Vpar_0920	ENOG41084DP	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
Vpar_0923	ENOG4105DX0	Hemolysin A
Vpar_0924	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
Vpar_0926	ENOG4105XBY	Regulates arginine biosynthesis genes (By similarity)
Vpar_0927	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
Vpar_0928	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
Vpar_0929	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
Vpar_0930	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
Vpar_0931	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
Vpar_0933	ENOG4105C09	Bile acid
Vpar_0934	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
Vpar_0937	ENOG41073R8	VanW family
Vpar_0946	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
Vpar_0947	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
Vpar_0948	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
Vpar_0949	ENOG4105CB1	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity)
Vpar_0950	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
Vpar_0952	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
Vpar_0953	ENOG4108R6K	riboflavin synthase, subunit alpha
Vpar_0954	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
Vpar_0955	ENOG4105C7K	acetolactate synthase
Vpar_0961	ENOG41083P1	competence protein ComEA helix-hairpin-helix repeat protein
Vpar_0963	ENOG4107YWA	deoxycytidylate deaminase
Vpar_0964	ENOG4105C8T	Leucyl-tRNA synthetase
Vpar_0965	ENOG4105VRS	hydrolase family 18
Vpar_0966	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
Vpar_0967	ENOG4107QXI	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs (By similarity)
Vpar_0968	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
Vpar_0969	ENOG4105C79	DNA protecting protein DprA
Vpar_0970	ENOG4105C0P	Mg chelatase subunit ChlI
Vpar_0971	ENOG4105VFF	UPF0102 protein
Vpar_0972	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
Vpar_0976	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
Vpar_0977	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
Vpar_0979	ENOG4105CKT	filamentous hemagglutinin
Vpar_0984	ENOG4105QUH	Domain of unknown function (DUF2088)
Vpar_0985	ENOG4105C8M	UPF0272 protein
Vpar_0986	ENOG4105DTC	1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (air) carboxylase
Vpar_0989	ENOG4105C37	(CBS) domain
Vpar_0990	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
Vpar_0992	ENOG4105C9A	Phoh family
Vpar_0993	ENOG4105N5T	Radical SAM Protein
Vpar_0996	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
Vpar_0997	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
Vpar_0999	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
Vpar_1000	ENOG4105C4R	Atp-dependent dna helicase
Vpar_1001	ENOG4105E2M	Manganese-dependent inorganic pyrophosphatase
Vpar_1004	ENOG4107XNU	peptidase
Vpar_1006	ENOG4108W8G	Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP (By similarity)
Vpar_1008	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
Vpar_1009	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
Vpar_1010	ENOG4105XZU	Preprotein translocase, subunit SecG
Vpar_1011	ENOG4105QIV	RNA polymerase
Vpar_1013	ENOG4105C2N	RNA methyltransferase TrmH family group 3
Vpar_1014	ENOG4105KEB	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
Vpar_1015	ENOG4105C8N	cysteinyl-tRNA synthetase
Vpar_1016	ENOG4105C09	Bile acid
Vpar_1017	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
Vpar_1018	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
Vpar_1019	ENOG4105CTP	PilT protein domain protein
Vpar_1020	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
Vpar_1022	ENOG41066A3	ATP guanido phosphotransferase
Vpar_1023	ENOG4108Z0C	Uvrb UvrC protein
Vpar_1025	ENOG4105X3E	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
Vpar_1027	ENOG4107YH3	SUF system FeS assembly protein, NifU family
Vpar_1028	ENOG4105C9B	Cysteine desulfurase
Vpar_1034	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
Vpar_1035	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
Vpar_1039	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
Vpar_1040	ENOG41072GX	Peptidase M22 Glycoprotease
Vpar_1041	ENOG4105K8N	protein family UPF0079, ATPase
Vpar_1042	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
Vpar_1044	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
Vpar_1045	ENOG4105EGY	DNA internalization-related competence protein ComEC Rec2
Vpar_1046	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
Vpar_1047	ENOG41082V8	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
Vpar_1049	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
Vpar_1052	ENOG41071I4	Phosphatidylserine decarboxylase proenzyme
Vpar_1054	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
Vpar_1055	ENOG41069HH	4-oxalocrotonate tautomerase
Vpar_1058	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
Vpar_1059	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
Vpar_1063	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
Vpar_1064	ENOG4108JQC	penicillin-binding protein 1A
Vpar_1065	ENOG4105C98	muts2 protein
Vpar_1066	ENOG4105CFP	Peptidase U32
Vpar_1067	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
Vpar_1068	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
Vpar_1070	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
Vpar_1071	ENOG4105C19	ABC transporter
Vpar_1072	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
Vpar_1074	ENOG4107ZC0	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
Vpar_1083	ENOG4105D7Q	type ii secretion system
Vpar_1084	ENOG4105CZX	twitching motility protein
Vpar_1085	ENOG4107QHF	type ii secretion system protein e
Vpar_1088	ENOG4105CP7	Triose-phosphate isomerase
Vpar_1089	ENOG4105BZA	Phosphoglycerate kinase
Vpar_1093	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
Vpar_1094	ENOG4108YZG	isomerase
Vpar_1095	ENOG4107WAU	Protein tyrosine phosphatase
Vpar_1096	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
Vpar_1097	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
Vpar_1098	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
Vpar_1099	ENOG4105CBJ	Metal-dependent enzyme
Vpar_1100	ENOG41082DI	50s ribosomal protein l31
Vpar_1103	ENOG4105CSM	endonuclease III
Vpar_1107	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
Vpar_1111	ENOG4105CPF	Cell wall formation (By similarity)
Vpar_1112	ENOG4105DFU	Cell wall formation (By similarity)
Vpar_1114	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
Vpar_1115	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
Vpar_1116	ENOG4107EES	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity)
Vpar_1117	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
Vpar_1119	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
Vpar_1120	ENOG4108V6E	Cell division protein mraZ
Vpar_1121	ENOG4105K63	Thioredoxin
Vpar_1123	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
Vpar_1127	ENOG4108YZ8	Superoxide reductase
Vpar_1128	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
Vpar_1129	ENOG4105C0Y	Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
Vpar_1130	ENOG4105DVK	Precorrin-2 c20-methyltransferase
Vpar_1131	ENOG4107PPM	cobalt chelatase
Vpar_1135	ENOG4107PPM	cobalt chelatase
Vpar_1137	ENOG4105E0A	ABC, transporter
Vpar_1138	ENOG4108U1V	ABC transporter, permease
Vpar_1139	ENOG41081F0	Precorrin-8x methylmutase
Vpar_1140	ENOG4105QUC	reductase
Vpar_1141	ENOG4105E4R	Precorrin-3B C17-methyltransferase
Vpar_1142	ENOG4108P62	biosynthesis protein (CbiG)
Vpar_1143	ENOG4105CIA	precorrin-4 C(11)-methyltransferase
Vpar_1144	ENOG4107XSI	cobalt-precorrin-6y C15-methyltransferase
Vpar_1146	ENOG4105EE8	May catalyze the methylation of C-1 in cobalt-precorrin- 5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A (By similarity)
Vpar_1147	ENOG4108VPT	UPF0234 protein
Vpar_1149	ENOG4105EMS	pseudouridine synthase
Vpar_1150	ENOG4105D2N	Aldolase
Vpar_1151	ENOG4105CKP	Polysaccharide Biosynthesis Protein
Vpar_1156	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
Vpar_1167	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
Vpar_1168	ENOG4105VJV	50s ribosomal protein L35
Vpar_1169	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
Vpar_1170	ENOG4107QPK	)-transporter
Vpar_1171	ENOG4107RGD	Major Facilitator superfamily
Vpar_1172	ENOG4105C22	threonyL-tRNA synthetase
Vpar_1175	ENOG4105CFP	Peptidase U32
Vpar_1176	ENOG4108VQJ	O-methyltransferase
Vpar_1179	ENOG4108Z08	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
Vpar_1181	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
Vpar_1183	ENOG4105CKK	Glycosyl transferase, family 2
Vpar_1185	ENOG4108USZ	hydrogenase
Vpar_1188	ENOG4105E3S	small subunit
Vpar_1189	ENOG4105K63	Thioredoxin
Vpar_1190	ENOG4105EGD	dinuclear metal center protein, YbgI family
Vpar_1193	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
Vpar_1195	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
Vpar_1196	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
Vpar_1197	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
Vpar_1198	ENOG410902V	Modulates RecA activity (By similarity)
Vpar_1199	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
Vpar_1200	ENOG4105CEV	competence damage-inducible protein
Vpar_1201	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
Vpar_1205	ENOG4105CNU	cell division protein FtsK
Vpar_1207	ENOG4105C9M	aspartyl-trna synthetase
Vpar_1209	ENOG4105D4P	Coproporphyrinogen iii oxidase
Vpar_1210	ENOG4105I3K	Ferric uptake regulator, Fur family
Vpar_1211	ENOG4105C5X	domain protein
Vpar_1212	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
Vpar_1213	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
Vpar_1214	ENOG4107QW8	radical SAM domain protein
Vpar_1215	ENOG4105K46	50S ribosomal protein l27
Vpar_1217	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
Vpar_1218	ENOG4108UI1	Probably functions as a manganese efflux pump (By similarity)
Vpar_1219	ENOG4105C03	ribonuclease
Vpar_1222	ENOG4105CNI	cell division protein FtsW
Vpar_1224	ENOG4105CJN	penicillin-binding protein
Vpar_1226	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
Vpar_1227	ENOG4105DFF	Rod shape-determining protein mreb
Vpar_1228	ENOG4105W5Q	DNA repair protein (RadC
Vpar_1229	ENOG4108Z03	MAF-like protein
Vpar_1233	ENOG4105CDE	UPF0348 protein
Vpar_1234	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
Vpar_1235	ENOG4105C34	Pseudouridine synthase
Vpar_1236	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
Vpar_1238	ENOG4107QWE	)-transporter
Vpar_1240	ENOG4105D9Q	decarboxylase (Beta subunit)
Vpar_1241	ENOG4105PV1	biotin lipoyl attachment domaiN-containing protein
Vpar_1244	ENOG4107QX3	carboxylase
Vpar_1245	ENOG4108ZVT	methylmalonyl-coA epimerase
Vpar_1247	ENOG4105D5P	Methylmalonyl-coA mutase
Vpar_1249	ENOG4105CYC	Transferase
Vpar_1251	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
Vpar_1252	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
Vpar_1253	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
Vpar_1255	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
Vpar_1256	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
Vpar_1257	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
Vpar_1258	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
Vpar_1259	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
Vpar_1260	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
Vpar_1261	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
Vpar_1262	ENOG4105Q2H	domain protein
Vpar_1263	ENOG4107T6J	Ribulose-1,5-bisphosphate carboxylase oxygenase large subunit
Vpar_1264	ENOG4105C2W	permease
Vpar_1267	ENOG4105BZ8	glutamate synthase
Vpar_1268	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
Vpar_1269	ENOG4105C5B	carbamate kinase
Vpar_1270	ENOG4105IW6	Carbamoyltransferase
Vpar_1271	ENOG4107S4Y	M20 DapE family protein YgeY
Vpar_1272	ENOG4107RCH	Diaminopropionate ammonia-lyase
Vpar_1274	ENOG4108Z29	Flavodoxin
Vpar_1278	ENOG4105C5I	Dehydrogenase
Vpar_1279	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
Vpar_1280	ENOG4105CPB	ATP-dependent endonuclease of the OLD family
Vpar_1282	ENOG4105D98	threonine synthase
Vpar_1283	ENOG4105EZR	dyp-type peroxidase family protein
Vpar_1285	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
Vpar_1287	ENOG4105C2W	permease
Vpar_1288	ENOG410908R	Methenyltetrahydrofolate cyclohydrolase
Vpar_1289	ENOG4105CKU	formyltetrahydrofolate synthetase
Vpar_1291	ENOG4107GFK	fumarate
Vpar_1292	ENOG4106DSS	Tartrate dehydratase subunit alpha
Vpar_1293	ENOG41075H3	AraC family transcriptional regulator
Vpar_1295	ENOG41075H3	AraC family transcriptional regulator
Vpar_1300	ENOG4105N67	Proton-coupled thiamine transporter YuaJ
Vpar_1301	ENOG4107SJ1	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides (By similarity)
Vpar_1302	ENOG4106UW1	Major Facilitator superfamily
Vpar_1305	ENOG4105C8Y	Acetylornithine aminotransferase
Vpar_1306	ENOG4105CAS	nag kinase
Vpar_1307	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
Vpar_1309	ENOG4105CH2	amidohydrolase
Vpar_1311	ENOG4108V2W	Carbonate dehydratase
Vpar_1312	ENOG4108ZP8	Acetolactate synthase small subunit
Vpar_1313	ENOG4105C7K	acetolactate synthase
Vpar_1315	ENOG4105X71	Membrane
Vpar_1318	ENOG4108V0P	LemA family
Vpar_1324	ENOG4105CI3	gtp-binding protein typa
Vpar_1326	ENOG4105D4A	Cell wall formation (By similarity)
Vpar_1327	ENOG4105WZB	UPF0342 protein
Vpar_1328	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
Vpar_1330	ENOG4107WCI	zn-dependent hydrolase of the beta-lactamase fold-like protein
Vpar_1334	ENOG4107ZYR	domain protein
Vpar_1335	ENOG4105CZN	Potassium uptake protein
Vpar_1336	ENOG4108MGF	sugar kinase
Vpar_1337	ENOG4105D4P	Coproporphyrinogen iii oxidase
Vpar_1340	ENOG4109015	Biopolymer transport protein exbD tolR
Vpar_1342	ENOG4105D05	Receptor
Vpar_1343	ENOG4105D05	Receptor
Vpar_1343	ENOG4105D05	Receptor
Vpar_1344	ENOG4105FTV	AraC Family Transcriptional Regulator
Vpar_1349	ENOG4108ESU	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane (By similarity)
Vpar_1350	ENOG4105E0A	ABC, transporter
Vpar_1353	ENOG4105CJ3	phosphate transporter
Vpar_1355	ENOG4107QHI	-hydrogenase
Vpar_1356	ENOG4105C5H	ABC transporter
Vpar_1359	ENOG4105K70	DNA-binding protein
Vpar_1360	ENOG4105DXN	mazG family
Vpar_1361	ENOG4105CKP	Polysaccharide Biosynthesis Protein
Vpar_1362	ENOG4108JA2	transcriptioN-repair coupling factor
Vpar_1363	ENOG4107QWP	ABC-2 type transporter
Vpar_1364	ENOG4107QWP	ABC-2 type transporter
Vpar_1365	ENOG4105CJ1	ABC, transporter
Vpar_1369	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
Vpar_1371	ENOG4107ZE5	PPIases accelerate the folding of proteins
Vpar_1372	ENOG4105CUZ	uba thif-type nad fad binding protein
Vpar_1374	ENOG4105EYH	Exonuclease
Vpar_1376	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
Vpar_1377	ENOG4107XWZ	ferric uptake regulator
Vpar_1378	ENOG4105C1J	atp-dependent rna helicase
Vpar_1381	ENOG4105BZC	d-serine deaminase
Vpar_1382	ENOG4105C26	Dehydrogenase
Vpar_1384	ENOG4108YYV	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity)
Vpar_1385	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
Vpar_1386	ENOG4105C9U	ATP-dependent DNA helicase RecQ
Vpar_1387	ENOG4105CK7	Sodium proline symporter
Vpar_1389	ENOG4106R49	Methyltransferase
Vpar_1391	ENOG4107RSM	transcriptional regulator
Vpar_1399	ENOG4105CHY	citrate lyase, alpha
Vpar_1400	ENOG4105CI0	Citrate lyase
Vpar_1401	ENOG4105XGS	Covalent carrier of the coenzyme of citrate lyase (By similarity)
Vpar_1402	ENOG4107QPK	)-transporter
Vpar_1403	ENOG4108KAM	Transcriptional regulator
Vpar_1404	ENOG4105HFZ	Membrane
Vpar_1406	ENOG4105C0B	DNA polymerase III (alpha subunit)
Vpar_1413	ENOG4105CKT	filamentous hemagglutinin
Vpar_1422	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
Vpar_1423	ENOG4105D52	delta-aminolevulinic acid dehydratase
Vpar_1424	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
Vpar_1425	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
Vpar_1426	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
Vpar_1427	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
Vpar_1428	ENOG4105DBK	s4 domain protein
Vpar_1430	ENOG4105VR5	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (By similarity)
Vpar_1431	ENOG4105DFA	alanine racemase domain protein
Vpar_1432	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
Vpar_1433	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
Vpar_1436	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
Vpar_1437	ENOG4105DKW	ABC transporter
Vpar_1439	ENOG4105C7K	acetolactate synthase
Vpar_1440	ENOG4105C7B	Threonine dehydratase
Vpar_1441	ENOG4105C01	Dihydroxy-acid dehydratase
Vpar_1443	ENOG4107QPK	)-transporter
Vpar_1444	ENOG4105G2U	Cupin 2, conserved barrel domain protein
Vpar_1446	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
Vpar_1447	ENOG4108Q79	6-phosphogluconolactonase (EC 3.1.1.31)
Vpar_1448	ENOG4105CGU	Enoyl-CoA hydratase
Vpar_1449	ENOG4108UJD	30S ribosomal protein S9
Vpar_1450	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
Vpar_1453	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
Vpar_1454	ENOG4105DZ2	Transcriptional regulator
Vpar_1455	ENOG4105KK4	UPF0060 membrane protein
Vpar_1456	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
Vpar_1457	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
Vpar_1459	ENOG4105UQX	Mate efflux family protein
Vpar_1460	ENOG4105DQU	oxidoreductase, subunit beta
Vpar_1461	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
Vpar_1462	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
Vpar_1463	ENOG4105EK6	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity)
Vpar_1464	ENOG4108JJB	ABC transporter
Vpar_1465	ENOG4108JJB	ABC transporter
Vpar_1466	ENOG4108ZT0	50S ribosomal protein l17
Vpar_1467	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
Vpar_1468	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
Vpar_1469	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
Vpar_1470	ENOG41067V7	50S ribosomal protein L36
Vpar_1474	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
Vpar_1475	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
Vpar_1476	ENOG4105VPB	50S ribosomal protein L30
Vpar_1477	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
Vpar_1478	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
Vpar_1480	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
Vpar_1481	ENOG41082QR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
Vpar_1482	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
Vpar_1484	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
Vpar_1487	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
Vpar_1488	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
Vpar_1489	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
Vpar_1490	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
Vpar_1491	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
Vpar_1492	ENOG41080UE	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
Vpar_1493	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
Vpar_1494	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
Vpar_1495	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
Vpar_1496	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
Vpar_1498	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
Vpar_1499	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
Vpar_1501	ENOG4105C94	Transporter
Vpar_1502	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
Vpar_1503	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
Vpar_1504	ENOG4108IJ0	Aspartate ammonia-lyase
Vpar_1505	ENOG4107SH3	glycosyl transferase, family 39
Vpar_1506	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
Vpar_1509	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
Vpar_1510	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
Vpar_1511	ENOG410683Z	Preprotein translocase SecE subunit
Vpar_1513	ENOG4105DSQ	Nitric oxide reductase
Vpar_1514	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
Vpar_1517	ENOG4107RSS	Hydrogenase accessory protein HypB
Vpar_1519	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
Vpar_1520	ENOG4105CJN	penicillin-binding protein
Vpar_1521	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
Vpar_1522	ENOG4105EJQ	L-serine dehydratase
Vpar_1524	ENOG4105EJ7	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity)
Vpar_1529	ENOG4106DSS	Tartrate dehydratase subunit alpha
Vpar_1531	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
Vpar_1534	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
Vpar_1535	ENOG4107YZM	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
Vpar_1536	ENOG4107ZFM	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
Vpar_1537	ENOG4105WS6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
Vpar_1538	ENOG4107RFS	it plays a direct role in the translocation of protons across the membrane (By similarity)
Vpar_1541	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
Vpar_1542	ENOG4105ESV	Glycosyl transferase, family 4
Vpar_1543	ENOG4105CAG	UPF0210 protein
Vpar_1544	ENOG4105VUC	UPF0237 protein
Vpar_1545	ENOG4107QIX	Phosphoglucomutase (EC 5.4.2.2
Vpar_1546	ENOG4108JYZ	YitT family
Vpar_1547	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
Vpar_1548	ENOG4105DRR	Transcriptional regulator, GntR family
Vpar_1550	ENOG4105D82	Glutamate dehydrogenase
Vpar_1552	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
Vpar_1553	ENOG4105CGK	Exodeoxyribonuclease III
Vpar_1556	ENOG4105M6F	mutator MutT protein
Vpar_1559	ENOG4107RRN	ABC transporter substrate-binding protein
Vpar_1562	ENOG4107RNA	Nickel ABC transporter, periplasmic nickel-binding protein
Vpar_1563	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
Vpar_1566	ENOG4105D5Q	Arginine ornithine antiporter
Vpar_1567	ENOG4105CH7	arginosuccinase
Vpar_1571	ENOG4108JQC	penicillin-binding protein 1A
Vpar_1573	ENOG4105KZ7	phosphocarrier protein hpr
Vpar_1574	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
Vpar_1575	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
Vpar_1576	ENOG4105DFD	Na H antiporter
Vpar_1577	ENOG4105DE4	1-phosphofructokinase
Vpar_1578	ENOG4105DM4	PTS System
Vpar_1580	ENOG4105C6T	cysteine synthase
Vpar_1581	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
Vpar_1582	ENOG4105D3R	alkyl hydroperoxide reductase
Vpar_1584	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
Vpar_1585	ENOG4105C75	arginyL-tRNA synthetase
Vpar_1590	ENOG4108X4Q	Hydrolase
Vpar_1594	ENOG4108J2R	molybdopterin oxidoreductase
Vpar_1595	ENOG4105DG4	malate L-lactate dehydrogenase
Vpar_1598	ENOG4105C2C	drug resistance transporter, Bcr CflA
Vpar_1600	ENOG4105D01	(LipO)protein
Vpar_1602	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
Vpar_1606	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
Vpar_1607	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
Vpar_1610	ENOG4108JPM	phospho-2-dehydro-3-deoxyheptonate aldolase
Vpar_1612	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
Vpar_1613	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
Vpar_1614	ENOG4105CQC	Prephenate dehydratase
Vpar_1618	ENOG4105FF2	Type I DHQase
Vpar_1619	ENOG4105C6X	Major Facilitator
Vpar_1620	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
Vpar_1621	ENOG4105C7N	Xanthine uracil vitamin C permease
Vpar_1627	ENOG4105C85	amino acid
Vpar_1631	ENOG4105C34	Pseudouridine synthase
Vpar_1634	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
Vpar_1635	ENOG410816I	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
Vpar_1636	ENOG4105C6E	dna polymerase iii
Vpar_1638	ENOG4105C34	Pseudouridine synthase
Vpar_1643	ENOG4105KMT	branched-chain amino acid
Vpar_1644	ENOG4108UMN	azlc family
Vpar_1645	ENOG4108I6A	alcohol dehydrogenase
Vpar_1646	ENOG4105D01	(LipO)protein
Vpar_1648	ENOG4107QZF	nitrite reductase NADPH large subunit
Vpar_1650	ENOG4108ZZK	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity)
Vpar_1651	ENOG4107QR9	Iron-sulfur cluster binding protein
Vpar_1652	ENOG4107R5T	Cysteine-rich domain
Vpar_1654	ENOG4107GBW	cellulosome anchoring protein cohesin
Vpar_1656	ENOG4105EPD	Oligopeptide transporter, Opt family
Vpar_1658	ENOG4107RN3	metallophosphoesterase
Vpar_1664	ENOG4105QZY	s-layer domain protein
Vpar_1666	ENOG4107Z6W	Protein CrcB homolog
Vpar_1669	ENOG4105CBD	Diacylglycerol kinase
Vpar_1670	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
Vpar_1671	ENOG4105C5N	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
Vpar_1677	ENOG4105R40	Glycine betaine carnitine choline
Vpar_1679	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
Vpar_1681	ENOG4105CDU	Replicative dna helicase
Vpar_1682	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
Vpar_1683	ENOG4105BZR	domain protein
Vpar_1685	ENOG4105CN5	Metallo-Beta-Lactamase
Vpar_1688	ENOG4105D7T	ABC transporter
Vpar_1689	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
Vpar_1690	ENOG4107Z6I	Thiamine biosynthesis protein
Vpar_1691	ENOG4105SA9	Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
Vpar_1692	ENOG4107T5V	SNARE associated Golgi
Vpar_1693	ENOG4105E0A	ABC, transporter
Vpar_1694	ENOG4105DQ5	transport system permease protein
Vpar_1696	ENOG4105D05	Receptor
Vpar_1702	ENOG4105XTM	Inherit from NOG: Mn2 dependent serine threonine protein kinase
Vpar_1703	ENOG41086B8	CoB-CoM heterodisulfide reductase
Vpar_1704	ENOG4105E33	succinate dehydrogenase
Vpar_1705	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
Vpar_1707	ENOG4105GR3	Histidine kinase
Vpar_1708	ENOG4106BRA	Membrane
Vpar_1709	ENOG4106BRA	Membrane
Vpar_1711	ENOG4105KVH	Transcriptional regulator
Vpar_1712	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
Vpar_1713	ENOG4108V06	Glutathione peroxidase
Vpar_1716	ENOG4108IJ2	phosphate acetyltransferase
Vpar_1719	ENOG4105BZ8	glutamate synthase
Vpar_1720	ENOG4105C87	Aminotransferase class I and II
Vpar_1722	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
Vpar_1724	ENOG4108W5N	phosphatidylglycerophosphatase a
Vpar_1726	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
Vpar_1729	ENOG4105VUF	Transcriptional regulator
Vpar_1733	ENOG4105DYS	nad(p)h dehydrogenase (quinone)
Vpar_1740	ENOG4107SQC	5-methylcytosine-specific restriction enzyme subunit McrC
Vpar_1741	ENOG4105FBQ	ATPase associated with various cellular activities aaa_5
Vpar_1745	ENOG4105CH6	catalase
Vpar_1747	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
Vpar_1749	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
Vpar_1750	ENOG4107VRI	Transcriptional regulator
Vpar_1753	ENOG4105C83	adenylosuccinate lyase
Vpar_1761	ENOG4105DJT	lAO AO transport system ATPase
Vpar_1762	ENOG4105D5P	Methylmalonyl-coA mutase
Vpar_1763	ENOG4105D5P	Methylmalonyl-coA mutase
Vpar_1764	ENOG4105FR1	rard protein
Vpar_1768	ENOG4105CQB	FAD linked oxidase domain protein
Vpar_1772	ENOG4105C0A	alcohol dehydrogenase
Vpar_1778	ENOG4105K56	Transcriptional regulator
Vpar_1781	ENOG4105CXY	transporter
Vpar_1783	ENOG41080E8	Transcriptional regulator, Spx MgsR family
Vpar_1784	ENOG4105VDM	plasmid maintenance system antidote protein, xre family
Vpar_1785	ENOG41080ET	plasmid maintenance system killer protein
Vpar_1788	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
Vpar_1800	ENOG4108QA2	CRISPR-associated protein, Csm6
Vpar_1801	ENOG4105GIM	CRISPR-associated protein cas6
Vpar_1802	ENOG4105G15	CRISPR-associated RAMP protein, Csm5 family
Vpar_1803	ENOG4108T47	CRISPR-associated RAMP protein, Csm4 family
Vpar_1804	ENOG4108W8W	CRISPR-associated RAMP protein, Csm3 family
Vpar_1806	ENOG410695F	Crispr-associated protein, Csm1 family
Vpar_1829	ENOG4105D17	glycoside hydrolase, family 3 domain protein
Vpar_1830	ENOG4107QHI	-hydrogenase
Vpar_1833	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
Vpar_1835	ENOG4105PW4	Sugar fermentation stimulation protein homolog
Vpar_1836	ENOG4108IFG	nitrite reductase, (NAD(P)H)
Vpar_1843	ENOG4106D5S	Corrinoid adenosyltransferase BtuR CobO CobP
Vpar_1844	ENOG4105E4C	Lytic transglycosylase catalytic
Vpar_1846	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
Vpar_1847	ENOG4105FA0	parb-like partition protein
Vpar_1848	ENOG4107QJE	Chromosome Partitioning Protein
Vpar_1850	ENOG4105C3R	Methionine synthase
Vpar_1852	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
Vpar_1853	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
Vpar_1854	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
Vpar_1855	ENOG4108Z7S	Single-stranded nucleic acid binding R3H domain-containing protein
Vpar_1856	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
Vpar_1857	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
Vpar_1858	ENOG4105M7T	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
Vpar_1859	ENOG4105VG0	50S ribosomal protein l34