locus-tag	class	description
OGM58_00020	COG1051	belongs to the nudix hydrolase family
OGM58_00050	COG0671	phosphoesterase, PA-phosphatase related
OGM58_00060	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
OGM58_00080	COG0516	GMP reductase activity
OGM58_00080	COG0517	IMP dehydrogenase activity
OGM58_00170	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
OGM58_00200	COG0583	DNA-binding transcription factor activity
OGM58_00235	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
OGM58_00265	COG2861	carbohydrate metabolic process
OGM58_00285	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
OGM58_00310	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OGM58_00315	COG0196	riboflavin kinase activity
OGM58_00320	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
OGM58_00325	COG2404	hydrolase activity, acting on ester bonds
OGM58_00330	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
OGM58_00335	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
OGM58_00345	COG2740	Nucleic-acid-binding protein implicated in transcription termination
OGM58_00350	COG0195	Participates in both transcription termination and antitermination
OGM58_00355	COG0779	Required for maturation of 30S ribosomal subunits
OGM58_00365	COG0741	lytic transglycosylase activity
OGM58_00370	COG0237	dephospho-CoA kinase activity
OGM58_00435	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
OGM58_00440	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
OGM58_00445	COG1012	belongs to the aldehyde dehydrogenase family
OGM58_00455	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
OGM58_00460	COG3189	MarR family transcriptional regulator
OGM58_00465	COG0459	protein refolding
OGM58_00470	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
OGM58_00490	COG0812	UDP-N-acetylmuramate dehydrogenase activity
OGM58_00510	COG0335	large ribosomal subunit rRNA binding
OGM58_00535	COG4372	Transposase
OGM58_00545	COG1137	ATPase activity
OGM58_00565	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
OGM58_00575	COG2877	3-deoxy-8-phosphooctulonate synthase activity
OGM58_00580	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
OGM58_00585	COG1663	tetraacyldisaccharide 4'-kinase activity
OGM58_00590	COG1519	Transferase
OGM58_00595	COG1132	(ABC) transporter
OGM58_00600	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
OGM58_00605	COG3494	Protein of unknown function (DUF1009)
OGM58_00610	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
OGM58_00615	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
OGM58_00625	COG1253	flavin adenine dinucleotide binding
OGM58_00630	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
OGM58_00645	COG1702	phosphate starvation-inducible protein PhoH
OGM58_00655	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
OGM58_00655	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
OGM58_00670	COG0583	DNA-binding transcription factor activity
OGM58_00675	COG2801	Transposase and inactivated derivatives
OGM58_00690	COG0513	Belongs to the DEAD box helicase family
OGM58_00695	COG4771	TonB-dependent receptor
OGM58_00710	COG1473	amidohydrolase
OGM58_00720	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
OGM58_00725	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
OGM58_00730	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
OGM58_00785	COG1115	amino acid carrier protein
OGM58_00805	COG3706	GGDEF domain
OGM58_00835	COG3279	Response regulator of the LytR AlgR family
OGM58_00840	COG2852	Protein conserved in bacteria
OGM58_00850	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
OGM58_00870	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
OGM58_00875	COG0352	thiamine-phosphate diphosphorylase activity
OGM58_00875	COG0351	phosphomethylpyrimidine kinase
OGM58_00895	COG2801	Transposase and inactivated derivatives
OGM58_00940	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
OGM58_00965	COG0218	Necessary for normal cell division and for the maintenance of normal septation
OGM58_00970	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
OGM58_00975	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
OGM58_00980	COG0740	serine-type endopeptidase activity
OGM58_00985	COG0544	peptidyl-prolyl cis-trans isomerase activity
OGM58_01000	COG0583	DNA-binding transcription factor activity
OGM58_01025	COG0463	Glycosyl transferase, family 2
OGM58_01030	COG1126	abc transporter atp-binding protein
OGM58_01035	COG0765	amino acid transport
OGM58_01040	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OGM58_01045	COG1088	dTDP-glucose 4,6-dehydratase activity
OGM58_01090	COG3328	transposase activity
OGM58_01105	COG1028	Short-chain dehydrogenase reductase Sdr
OGM58_01115	COG0564	pseudouridine synthase activity
OGM58_01180	COG0778	Nitroreductase
OGM58_01195	COG2801	Transposase and inactivated derivatives
OGM58_01200	COG0473	3-isopropylmalate dehydrogenase activity
OGM58_01205	COG0066	3-isopropylmalate dehydratase activity
OGM58_01225	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OGM58_01260	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
OGM58_01280	COG2801	Transposase and inactivated derivatives
OGM58_01290	COG0826	peptidase U32
OGM58_01295	COG4122	O-methyltransferase activity
OGM58_01300	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
OGM58_01320	COG2252	PERMEase
OGM58_01330	COG1686	Belongs to the peptidase S11 family
OGM58_01340	COG2801	Transposase and inactivated derivatives
OGM58_01350	COG1757	Na H antiporter
OGM58_01355	COG1695	Transcriptional regulator
OGM58_01390	COG0463	Glycosyl transferase, family 2
OGM58_01395	COG1850	ribulose-bisphosphate carboxylase activity
OGM58_01405	COG3206	protein involved in exopolysaccharide biosynthesis
OGM58_01425	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
OGM58_01430	COG0747	negative chemotaxis
OGM58_01435	COG0444	Belongs to the ABC transporter superfamily
OGM58_01440	COG4608	Belongs to the ABC transporter superfamily
OGM58_01445	COG2271	Major facilitator Superfamily
OGM58_01475	COG1971	Probably functions as a manganese efflux pump
OGM58_01480	COG0546	phosphoglycolate phosphatase activity
OGM58_01490	COG0662	Cupin 2, conserved barrel domain protein
OGM58_01495	COG2358	TRAP transporter, solute receptor (TAXI family
OGM58_01505	COG1362	aminopeptidase activity
OGM58_01535	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
OGM58_01545	COG0471	metal ion transport
OGM58_01545	COG0490	domain, Protein
OGM58_01550	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
OGM58_01560	COG0490	domain, Protein
OGM58_01560	COG0471	metal ion transport
OGM58_01570	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
OGM58_01580	COG0490	domain, Protein
OGM58_01580	COG0471	metal ion transport
OGM58_01585	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
OGM58_01595	COG0471	metal ion transport
OGM58_01595	COG0490	domain, Protein
OGM58_01630	COG1918	ferrous iron import across plasma membrane
OGM58_01630	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
OGM58_01650	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
OGM58_01655	COG0514	ATP-dependent DNA helicase (RecQ)
OGM58_01685	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
OGM58_01695	COG0655	NAD(P)H dehydrogenase (quinone) activity
OGM58_01710	COG0583	DNA-binding transcription factor activity
OGM58_01715	COG0657	acetylesterase activity
OGM58_01720	COG1846	Transcriptional regulator
OGM58_01730	COG0583	DNA-binding transcription factor activity
OGM58_01735	COG2814	Major facilitator Superfamily
OGM58_01740	COG0435	Glutathione S-transferase
OGM58_01750	COG0456	acetyltransferase
OGM58_01755	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OGM58_01760	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OGM58_01765	COG0765	amino acid transport
OGM58_01770	COG0765	amino acid transport
OGM58_01775	COG1847	R3H domain protein
OGM58_01780	COG0706	membrane insertase activity
OGM58_01785	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
OGM58_01790	COG0594	ribonuclease P activity
OGM58_01795	COG0230	Belongs to the bacterial ribosomal protein bL34 family
OGM58_01805	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
OGM58_01810	COG2195	Cleaves the N-terminal amino acid of tripeptides
OGM58_01830	COG0232	Belongs to the dGTPase family. Type 2 subfamily
OGM58_01835	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
OGM58_01840	COG0517	IMP dehydrogenase activity
OGM58_01845	COG0574	Belongs to the PEP-utilizing enzyme family
OGM58_01845	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
OGM58_01870	COG0038	chloride channel
OGM58_01880	COG2040	homocysteine
OGM58_01885	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OGM58_01890	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
OGM58_01900	COG0583	DNA-binding transcription factor activity
OGM58_01925	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
OGM58_01945	COG0656	L-ascorbic acid biosynthetic process
OGM58_01950	COG1464	Belongs to the NlpA lipoprotein family
OGM58_01955	COG0667	Aldo Keto reductase
OGM58_01985	COG1942	4-Oxalocrotonate Tautomerase
OGM58_02025	COG1733	regulation of RNA biosynthetic process
OGM58_02035	COG0656	L-ascorbic acid biosynthetic process
OGM58_02045	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
OGM58_02065	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
OGM58_02080	COG2267	carboxylic ester hydrolase activity
OGM58_02085	COG2226	methyltransferase
OGM58_02090	COG2226	methyltransferase
OGM58_02105	COG0497	DNA recombination
OGM58_02120	COG1739	Uncharacterized protein family UPF0029
OGM58_02175	COG0445	tRNA wobble uridine modification
OGM58_02180	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
OGM58_02185	COG1917	Cupin 2, conserved barrel domain protein
OGM58_02185	COG2169	Transcriptional regulator
OGM58_02205	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
OGM58_02215	COG1253	flavin adenine dinucleotide binding
OGM58_02235	COG5001	Diguanylate cyclase
OGM58_02265	COG2801	Transposase and inactivated derivatives
OGM58_02270	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
OGM58_02280	COG0318	PFAM AMP-dependent synthetase and ligase
OGM58_02295	COG3300	MHYT domain
OGM58_02295	COG5001	Diguanylate cyclase
OGM58_02335	COG1126	abc transporter atp-binding protein
OGM58_02340	COG0765	amino acid transport
OGM58_02345	COG0765	amino acid transport
OGM58_02355	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
OGM58_02360	COG0667	Aldo Keto reductase
OGM58_02405	COG2078	PFAM AMMECR1 domain protein
OGM58_02405	COG3885	ferrous iron binding
OGM58_02420	COG3263	regulation of cellular component size
OGM58_02425	COG3760	aminoacyl-tRNA metabolism involved in translational fidelity
OGM58_02555	COG3041	Addiction module toxin RelE StbE family
OGM58_02580	COG0860	N-Acetylmuramoyl-L-alanine amidase
OGM58_02600	COG1802	Transcriptional regulator
OGM58_02600	COG4626	Terminase
OGM58_02610	COG0740	serine-type endopeptidase activity
OGM58_02720	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
OGM58_02735	COG3842	ATPase activity
OGM58_02760	COG0640	Transcriptional regulator
OGM58_02785	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
OGM58_02790	COG1459	type II secretion system
OGM58_02835	COG0328	RNA-DNA hybrid ribonuclease activity
OGM58_02845	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
OGM58_02850	COG0592	DNA-directed DNA polymerase activity
OGM58_02860	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
OGM58_02875	COG2326	polyphosphate kinase activity
OGM58_02880	COG2326	polyphosphate kinase activity
OGM58_02910	COG1192	Involved in chromosome partitioning
OGM58_02915	COG1475	DNA binding
OGM58_02925	COG1388	LysM domain
OGM58_02925	COG4942	peptidase
OGM58_02940	COG2801	Transposase and inactivated derivatives
OGM58_03005	COG1115	amino acid carrier protein
OGM58_03010	COG1115	amino acid carrier protein
OGM58_03020	COG1115	amino acid carrier protein
OGM58_03030	COG1301	dicarboxylic acid transport
OGM58_03035	COG1115	amino acid carrier protein
OGM58_03040	COG2085	NADP oxidoreductase coenzyme F420-dependent
OGM58_03050	COG0018	arginyl-trna synthetase
OGM58_03055	COG0504	CTP synthase activity
OGM58_03085	COG3384	dioxygenase
OGM58_03090	COG4206	TonB-dependent receptor
OGM58_03110	COG5001	Diguanylate cyclase
OGM58_03110	COG3300	MHYT domain
OGM58_03130	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OGM58_03145	COG1619	proteins homologs of microcin C7 resistance protein MccF
OGM58_03185	COG2233	PERMEase
OGM58_03190	COG4771	TonB-dependent receptor
OGM58_03200	COG0006	proline dipeptidase activity
OGM58_03210	COG3875	lactate racemase activity
OGM58_03225	COG2194	sulfuric ester hydrolase activity
OGM58_03230	COG3875	lactate racemase activity
OGM58_03240	COG2855	membrane
OGM58_03250	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
OGM58_03260	COG1196	nuclear chromosome segregation
OGM58_03275	COG0863	Belongs to the N(4) N(6)-methyltransferase family
OGM58_03285	COG1061	Type III restriction enzyme res subunit
OGM58_03290	COG0494	nUDIX hydrolase
OGM58_03305	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
OGM58_03325	COG4974	Belongs to the 'phage' integrase family
OGM58_03350	COG2315	Protein conserved in bacteria
OGM58_03380	COG0583	DNA-binding transcription factor activity
OGM58_03385	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
OGM58_03420	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
OGM58_03420	COG0140	phosphoribosyl-ATP diphosphatase activity
OGM58_03425	COG0107	imidazoleglycerol-phosphate synthase activity
OGM58_03435	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
OGM58_03440	COG0131	Imidazoleglycerol-phosphate dehydratase
OGM58_03445	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
OGM58_03450	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
OGM58_03455	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
OGM58_03460	COG0124	histidyl-tRNA synthetase
OGM58_03520	COG0670	Belongs to the BI1 family
OGM58_03525	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
OGM58_03530	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
OGM58_03590	COG2801	Transposase and inactivated derivatives
OGM58_03595	COG1424	Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
OGM58_03600	COG0156	8-amino-7-oxononanoate synthase activity
OGM58_03610	COG3599	regulation of cell shape
OGM58_03630	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
OGM58_03635	COG0534	Mate efflux family protein
OGM58_03640	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
OGM58_03650	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
OGM58_03655	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
OGM58_03660	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
OGM58_03665	COG1605	Chorismate mutase
OGM58_03665	COG0077	Prephenate dehydratase
OGM58_03690	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
OGM58_03700	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
OGM58_03705	COG0359	binds to the 23S rRNA
OGM58_03710	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
OGM58_03740	COG0318	PFAM AMP-dependent synthetase and ligase
OGM58_03745	COG0242	peptide deformylase activity
OGM58_03750	COG2249	NAD(P)H dehydrogenase (quinone) activity
OGM58_03765	COG0640	Transcriptional regulator
OGM58_03770	COG0798	PFAM Bile acid sodium symporter
OGM58_03785	COG1959	2 iron, 2 sulfur cluster binding
OGM58_03845	COG2031	fatty acid transporter
OGM58_03850	COG0154	amidase activity
OGM58_03855	COG2962	Rard protein
OGM58_03870	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
OGM58_03885	COG1917	Cupin 2, conserved barrel domain protein
OGM58_03885	COG2207	Transcriptional regulator
OGM58_03905	COG0656	L-ascorbic acid biosynthetic process
OGM58_03925	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
OGM58_03935	COG0671	phosphoesterase, PA-phosphatase related
OGM58_03940	COG0671	phosphoesterase, PA-phosphatase related
OGM58_03955	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
OGM58_03960	COG0569	domain protein
OGM58_03965	COG0697	spore germination
OGM58_03975	COG0656	L-ascorbic acid biosynthetic process
OGM58_03980	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
OGM58_03995	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
OGM58_04000	COG0789	Transcriptional regulator
OGM58_04025	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
OGM58_04030	COG0426	domain, Protein
OGM58_04030	COG1773	rubredoxin
OGM58_04045	COG0490	domain, Protein
OGM58_04050	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
OGM58_04055	COG3959	Transketolase, thiamine diphosphate binding domain
OGM58_04060	COG3958	Transketolase
OGM58_04070	COG3206	protein involved in exopolysaccharide biosynthesis
OGM58_04080	COG1114	Component of the transport system for branched-chain amino acids
OGM58_04085	COG1114	Component of the transport system for branched-chain amino acids
OGM58_04090	COG0515	serine threonine protein kinase
OGM58_04105	COG1216	Glycosyl transferase, family 2
OGM58_04175	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
OGM58_04215	COG1683	Conserved Protein
OGM58_04220	COG1940	carbohydrate kinase activity
OGM58_04225	COG5001	Diguanylate cyclase
OGM58_04225	COG4251	negative regulation of phosphorylation
OGM58_04225	COG2203	Gaf domain
OGM58_04225	COG3706	GGDEF domain
OGM58_04240	COG2801	Transposase and inactivated derivatives
OGM58_04245	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
OGM58_04250	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
OGM58_04255	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
OGM58_04260	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
OGM58_04275	COG1691	(AIR) carboxylase
OGM58_04280	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
OGM58_04280	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
OGM58_04285	COG1121	(ABC) transporter
OGM58_04290	COG1108	ABC-type Mn2 Zn2 transport systems permease components
OGM58_04295	COG0803	Belongs to the bacterial solute-binding protein 9 family
OGM58_04305	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
OGM58_04310	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
OGM58_04315	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
OGM58_04335	COG1132	(ABC) transporter
OGM58_04340	COG1132	(ABC) transporter
OGM58_04355	COG1280	lysine exporter protein (LysE YggA)
OGM58_04370	COG0778	Nitroreductase
OGM58_04375	COG0251	oxidation-reduction process
OGM58_04390	COG2827	Endonuclease containing a URI domain
OGM58_04410	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
OGM58_04415	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
OGM58_04425	COG0583	DNA-binding transcription factor activity
OGM58_04430	COG0667	Aldo Keto reductase
OGM58_04445	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
OGM58_04465	COG0470	DNA polymerase III
OGM58_04465	COG1067	ATP-dependent peptidase activity
OGM58_04470	COG0305	Participates in initiation and elongation during chromosome replication
OGM58_04480	COG1376	ErfK ybiS ycfS ynhG family protein
OGM58_04495	COG1027	Aspartate ammonia-lyase
OGM58_04505	COG5001	Diguanylate cyclase
OGM58_04520	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
OGM58_04550	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
OGM58_04555	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
OGM58_04560	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
OGM58_04575	COG0356	it plays a direct role in the translocation of protons across the membrane
OGM58_04580	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
OGM58_04585	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
OGM58_04590	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
OGM58_04595	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
OGM58_04600	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
OGM58_04620	COG0583	DNA-binding transcription factor activity
OGM58_04625	COG3328	transposase activity
OGM58_04630	COG3118	belongs to the thioredoxin family
OGM58_04655	COG0602	queuosine metabolic process
OGM58_04660	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
OGM58_04660	COG1328	CTP reductase activity
OGM58_04665	COG0482	sulfurtransferase activity
OGM58_04670	COG1024	Enoyl-CoA hydratase
OGM58_04680	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
OGM58_04690	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
OGM58_04715	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
OGM58_04720	COG0187	DNA topoisomerase II activity
OGM58_04735	COG0786	glutamate:sodium symporter activity
OGM58_04740	COG1994	Peptidase M50
OGM58_04745	COG2860	membrane
OGM58_04750	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
OGM58_04755	COG0512	Glutamine amidotransferase of anthranilate synthase
OGM58_04755	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
OGM58_04760	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
OGM58_04765	COG0134	indole-3-glycerol-phosphate synthase activity
OGM58_04770	COG0133	tryptophan synthase activity
OGM58_04775	COG0159	tryptophan synthase activity
OGM58_04790	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
OGM58_04795	COG0720	synthase
OGM58_04800	COG0602	queuosine metabolic process
OGM58_04805	COG0302	gtp cyclohydrolase
OGM58_04820	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
OGM58_04825	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
OGM58_04835	COG0562	UDP-galactopyranose mutase
OGM58_04860	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
OGM58_04880	COG1216	Glycosyl transferase, family 2
OGM58_04890	COG1216	Glycosyl transferase, family 2
OGM58_04890	COG1442	glycosyl transferase family 8
OGM58_04930	COG1210	Utp--glucose-1-phosphate uridylyltransferase
OGM58_04935	COG0463	Glycosyl transferase, family 2
OGM58_04940	COG0463	Glycosyl transferase, family 2
OGM58_04955	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
OGM58_05000	COG0733	neurotransmitter:sodium symporter activity
OGM58_05005	COG0733	neurotransmitter:sodium symporter activity
OGM58_05010	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
OGM58_05020	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
OGM58_05030	COG0419	ATPase involved in DNA repair
OGM58_05035	COG3206	protein involved in exopolysaccharide biosynthesis
OGM58_05040	COG3206	protein involved in exopolysaccharide biosynthesis
OGM58_05045	COG3206	protein involved in exopolysaccharide biosynthesis
OGM58_05050	COG3206	protein involved in exopolysaccharide biosynthesis
OGM58_05055	COG1012	belongs to the aldehyde dehydrogenase family
OGM58_05060	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
OGM58_05060	COG0674	pyruvate-flavodoxin oxidoreductase activity
OGM58_05065	COG1013	pyruvate-flavodoxin oxidoreductase activity
OGM58_05085	COG2814	Major facilitator Superfamily
OGM58_05090	COG1924	4 iron, 4 sulfur cluster binding
OGM58_05105	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
OGM58_05110	COG2176	DNA-directed DNA polymerase activity
OGM58_05130	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
OGM58_05135	COG0049	tRNA binding
OGM58_05140	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
OGM58_05170	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
OGM58_05175	COG0088	Forms part of the polypeptide exit tunnel
OGM58_05180	COG0089	rRNA binding
OGM58_05190	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
OGM58_05195	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
OGM58_05205	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
OGM58_05210	COG0255	Belongs to the universal ribosomal protein uL29 family
OGM58_05215	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
OGM58_05220	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
OGM58_05230	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
OGM58_05240	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
OGM58_05245	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
OGM58_05250	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
OGM58_05255	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
OGM58_05260	COG1841	ribosomal large subunit assembly
OGM58_05270	COG0201	protein transport
OGM58_05275	COG0563	adenylate kinase activity
OGM58_05285	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
OGM58_05290	COG0257	Belongs to the bacterial ribosomal protein bL36 family
OGM58_05295	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
OGM58_05300	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
OGM58_05305	COG0202	RNA polymerase activity
OGM58_05310	COG0203	ribosomal protein L17
OGM58_05330	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
OGM58_05340	COG0745	RESPONSE REGULATOR receiver
OGM58_05365	COG0714	Associated with various cellular activities
OGM58_05375	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
OGM58_05380	COG2814	Major facilitator Superfamily
OGM58_05385	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OGM58_05390	COG1074	ATP-dependent DNA helicase activity
OGM58_05400	COG2814	Major facilitator Superfamily
OGM58_05405	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
OGM58_05410	COG0626	cystathionine gamma-synthase activity
OGM58_05420	COG0583	DNA-binding transcription factor activity
OGM58_05425	COG0066	3-isopropylmalate dehydratase activity
OGM58_05430	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
OGM58_05440	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
OGM58_05455	COG1464	Belongs to the NlpA lipoprotein family
OGM58_05465	COG0427	acetyl-CoA hydrolase
OGM58_05475	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
OGM58_05480	COG1703	isobutyryl-CoA mutase activity
OGM58_05490	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
OGM58_05505	COG0386	Belongs to the glutathione peroxidase family
OGM58_05510	COG0561	phosphatase activity
OGM58_05515	COG1122	ATPase activity
OGM58_05525	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
OGM58_05530	COG0101	tRNA pseudouridine synthase activity
OGM58_05535	COG1309	transcriptional regulator
OGM58_05565	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
OGM58_05570	COG1799	cell septum assembly
OGM58_05575	COG1799	cell septum assembly
OGM58_05580	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
OGM58_05595	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
OGM58_05610	COG2226	methyltransferase
OGM58_05615	COG0137	argininosuccinate synthase activity
OGM58_05620	COG0165	Argininosuccinate lyase
OGM58_05630	COG2116	formate transmembrane transporter activity
OGM58_05645	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
OGM58_05655	COG0583	DNA-binding transcription factor activity
OGM58_05660	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
OGM58_05675	COG0531	amino acid
OGM58_05685	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
OGM58_05690	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
OGM58_05695	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
OGM58_05715	COG2801	Transposase and inactivated derivatives
OGM58_05725	COG0227	Belongs to the bacterial ribosomal protein bL28 family
OGM58_05730	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
OGM58_05735	COG0516	GMP reductase activity
OGM58_05735	COG0517	IMP dehydrogenase activity
OGM58_05745	COG0688	phosphatidylethanolamine metabolic process
OGM58_05760	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
OGM58_05765	COG1937	Protein conserved in bacteria
OGM58_05775	COG0582	viral genome integration into host DNA
OGM58_05790	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
OGM58_05865	COG0629	single-stranded DNA binding
OGM58_05940	COG0740	serine-type endopeptidase activity
OGM58_06045	COG4974	Belongs to the 'phage' integrase family
OGM58_06100	COG0736	holo-[acyl-carrier-protein] synthase activity
OGM58_06105	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
OGM58_06105	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
OGM58_06110	COG0658	competence protein
OGM58_06110	COG2333	competence protein COMEC
OGM58_06140	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
OGM58_06145	COG0518	GMP synthase (glutamine-hydrolyzing) activity
OGM58_06145	COG0519	Catalyzes the synthesis of GMP from XMP
OGM58_06155	COG4943	cyclic-guanylate-specific phosphodiesterase activity
OGM58_06175	COG0559	Belongs to the binding-protein-dependent transport system permease family
OGM58_06195	COG0252	asparaginase activity
OGM58_06225	COG0561	phosphatase activity
OGM58_06235	COG0391	Required for morphogenesis under gluconeogenic growth conditions
OGM58_06240	COG1481	regulation of sporulation
OGM58_06250	COG4481	Protein conserved in bacteria
OGM58_06290	COG0267	Belongs to the bacterial ribosomal protein bL33 family
OGM58_06300	COG0250	Participates in transcription elongation, termination and antitermination
OGM58_06305	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
OGM58_06315	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
OGM58_06335	COG4684	Psort location CytoplasmicMembrane, score
OGM58_06345	COG2801	Transposase and inactivated derivatives
OGM58_06350	COG1671	Belongs to the UPF0178 family
OGM58_06365	COG1686	Belongs to the peptidase S11 family
OGM58_06375	COG1098	S1 RNA binding domain
OGM58_06380	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
OGM58_06380	COG0248	Ppx GppA phosphatase
OGM58_06390	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
OGM58_06395	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
OGM58_06400	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
OGM58_06425	COG1131	(ABC) transporter
OGM58_06430	COG0842	Transport permease protein
OGM58_06435	COG0842	Transport permease protein
OGM58_06440	COG1982	Orn Lys Arg decarboxylase major
OGM58_06445	COG1982	Orn Lys Arg decarboxylase major
OGM58_06450	COG0531	amino acid
OGM58_06455	COG1982	Orn Lys Arg decarboxylase major
OGM58_06460	COG3328	transposase activity
OGM58_06465	COG0583	DNA-binding transcription factor activity
OGM58_06485	COG0765	amino acid transport
OGM58_06490	COG0426	domain, Protein
OGM58_06500	COG2094	Belongs to the DNA glycosylase MPG family
OGM58_06505	COG1196	nuclear chromosome segregation
OGM58_06510	COG0552	protein localization to endoplasmic reticulum
OGM58_06525	COG0583	DNA-binding transcription factor activity
OGM58_06540	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
OGM58_06555	COG3875	lactate racemase activity
OGM58_06590	COG1823	symporter activity
OGM58_06625	COG0436	Aminotransferase
OGM58_06630	COG2197	response regulator
OGM58_06645	COG0700	Nucleoside recognition
OGM58_06660	COG1966	Carbon starvation protein
OGM58_06675	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
OGM58_06680	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
OGM58_06690	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
OGM58_06695	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
OGM58_06700	COG0281	malic enzyme
OGM58_06705	COG0617	tRNA 3'-terminal CCA addition
OGM58_06710	COG0768	penicillin binding
OGM58_06715	COG2759	Belongs to the formate--tetrahydrofolate ligase family
OGM58_06720	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
OGM58_06725	COG0668	transmembrane transport
OGM58_06730	COG0589	response to stress
OGM58_06735	COG0589	response to stress
OGM58_06745	COG0589	response to stress
OGM58_06750	COG0589	response to stress
OGM58_06760	COG3845	ABC transporter
OGM58_06765	COG1122	ATPase activity
OGM58_06775	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
OGM58_06790	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
OGM58_06795	COG1388	LysM domain
OGM58_06795	COG3584	3D domain protein
OGM58_06805	COG0564	pseudouridine synthase activity
OGM58_06810	COG3191	aminopeptidase activity
OGM58_06820	COG3118	belongs to the thioredoxin family
OGM58_06830	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
OGM58_06855	COG2194	sulfuric ester hydrolase activity
OGM58_06860	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
OGM58_06865	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
OGM58_06895	COG3328	transposase activity
OGM58_06905	COG1473	amidohydrolase
OGM58_06910	COG0700	Nucleoside recognition
OGM58_06945	COG2199	diguanylate cyclase activity
OGM58_06945	COG2200	EAL domain
OGM58_06945	COG2202	Pas domain
OGM58_06985	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
OGM58_06995	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
OGM58_07010	COG2358	TRAP transporter, solute receptor (TAXI family
OGM58_07040	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
OGM58_07060	COG0583	DNA-binding transcription factor activity
OGM58_07090	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
OGM58_07100	COG0540	Belongs to the ATCase OTCase family
OGM58_07105	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
OGM58_07110	COG0505	Belongs to the CarA family
OGM58_07115	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
OGM58_07120	COG0543	2 iron, 2 sulfur cluster binding
OGM58_07125	COG0167	dihydroorotate dehydrogenase activity
OGM58_07130	COG1115	amino acid carrier protein
OGM58_07135	COG1388	LysM domain
OGM58_07135	COG3584	3D domain protein
OGM58_07140	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
OGM58_07150	COG0193	aminoacyl-tRNA hydrolase activity
OGM58_07155	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
OGM58_07170	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
OGM58_07170	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
OGM58_07175	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
OGM58_07180	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
OGM58_07185	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
OGM58_07195	COG2136	Putative SAM-dependent methyltransferase
OGM58_07195	COG2521	methyltransferase
OGM58_07200	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
OGM58_07210	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
OGM58_07225	COG0697	spore germination
OGM58_07230	COG0697	spore germination
OGM58_07240	COG0635	Involved in the biosynthesis of porphyrin-containing compound
OGM58_07245	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
OGM58_07275	COG0646	methionine synthase
OGM58_07275	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
OGM58_07290	COG2731	YhcH YjgK YiaL family protein
OGM58_07315	COG0438	transferase activity, transferring glycosyl groups
OGM58_07320	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
OGM58_07320	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
OGM58_07345	COG2011	ABC-type metal ion transport system permease component
OGM58_07350	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
OGM58_07355	COG3328	transposase activity
OGM58_07360	COG4496	protein, YerC YecD
OGM58_07370	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OGM58_07380	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OGM58_07395	COG0495	leucyl-tRNA aminoacylation
OGM58_07405	COG3634	alkyl hydroperoxide reductase activity
OGM58_07425	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
OGM58_07430	COG0588	phosphoglycerate mutase activity
OGM58_07440	COG0802	atpase or kinase
OGM58_07445	COG1214	PFAM Peptidase M22, glycoprotease
OGM58_07450	COG0456	acetyltransferase
OGM58_07470	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
OGM58_07480	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
OGM58_07485	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
OGM58_07490	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
OGM58_07490	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
OGM58_07495	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
OGM58_07500	COG2244	polysaccharide biosynthetic process
OGM58_07515	COG2390	Transcriptional regulator
OGM58_07525	COG0126	phosphoglycerate kinase activity
OGM58_07530	COG0149	triose-phosphate isomerase activity
OGM58_07535	COG0148	phosphopyruvate hydratase activity
OGM58_07540	COG1227	inorganic diphosphatase activity
OGM58_07545	COG0210	DNA helicase
OGM58_07550	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
OGM58_07560	COG0154	amidase activity
OGM58_07565	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
OGM58_07575	COG0450	alkyl hydroperoxide reductase
OGM58_07585	COG1494	fructose-1,6-bisphosphatase
OGM58_07590	COG0681	Belongs to the peptidase S26 family
OGM58_07595	COG0436	Aminotransferase
OGM58_07600	COG0012	GTP binding
OGM58_07605	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
OGM58_07615	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
OGM58_07620	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
OGM58_07625	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
OGM58_07635	COG4864	UPF0365 protein
OGM58_07660	COG0791	NLP P60 protein
OGM58_07665	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
OGM58_07670	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
OGM58_07675	COG4472	Bacterial protein of unknown function (DUF965)
OGM58_07690	COG0420	3'-5' exonuclease activity
OGM58_07695	COG4717	serine-type aminopeptidase activity
OGM58_07705	COG0052	Belongs to the universal ribosomal protein uS2 family
OGM58_07710	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
OGM58_07715	COG0528	UMP kinase activity
OGM58_07720	COG0233	cytoplasmic translational termination
OGM58_07725	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
OGM58_07730	COG4589	Belongs to the CDS family
OGM58_07735	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
OGM58_07740	COG0750	zinc metalloprotease
OGM58_07745	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
OGM58_07750	COG0442	prolyl-tRNA aminoacylation
OGM58_07760	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
OGM58_07765	COG1040	competence protein
OGM58_07775	COG3858	chitin binding
OGM58_07805	COG3328	transposase activity
OGM58_07815	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OGM58_07820	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
OGM58_07835	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
OGM58_07840	COG0569	domain protein
OGM58_07845	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
OGM58_07860	COG0750	zinc metalloprotease
OGM58_07865	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
OGM58_07870	COG1127	ABC transporter
OGM58_07890	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
OGM58_07910	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
OGM58_07925	COG2814	Major facilitator Superfamily
OGM58_07930	COG0179	Fumarylacetoacetate (FAA) hydrolase
OGM58_07960	COG0436	Aminotransferase
OGM58_07970	COG1968	undecaprenyl-diphosphatase activity
OGM58_07980	COG0358	DNA primase activity
OGM58_07985	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
OGM58_07995	COG2384	SAM-dependent methyltransferase
OGM58_08015	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OGM58_08020	COG1323	Belongs to the UPF0348 family
OGM58_08035	COG2003	Belongs to the UPF0758 family
OGM58_08045	COG0811	peptide transport
OGM58_08055	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
OGM58_08065	COG1797	cobyrinic acid a,c-diamide synthase activity
OGM58_08085	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
OGM58_08105	COG2001	Belongs to the MraZ family
OGM58_08110	COG0275	rRNA processing
OGM58_08120	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
OGM58_08125	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
OGM58_08130	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
OGM58_08135	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
OGM58_08145	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
OGM58_08150	COG1181	Belongs to the D-alanine--D-alanine ligase family
OGM58_08165	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
OGM58_08170	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
OGM58_08180	COG0859	PFAM glycosyl transferase family 9
OGM58_08185	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
OGM58_08195	COG4492	Belongs to the UPF0735 family
OGM58_08200	COG0460	homoserine dehydrogenase
OGM58_08205	COG0083	homoserine kinase activity
OGM58_08215	COG0501	Belongs to the peptidase M48B family
OGM58_08220	COG0105	UTP biosynthetic process
OGM58_08230	COG0826	peptidase U32
OGM58_08235	COG1193	negative regulation of DNA recombination
OGM58_08245	COG1307	EDD domain protein, DegV family
OGM58_08260	COG3328	transposase activity
OGM58_08270	COG1492	cobalamin metabolic process
OGM58_08280	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
OGM58_08295	COG0406	alpha-ribazole phosphatase activity
OGM58_08300	COG0006	proline dipeptidase activity
OGM58_08305	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
OGM58_08320	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
OGM58_08325	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
OGM58_08335	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
OGM58_08340	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
OGM58_08345	COG0261	This protein binds to 23S rRNA in the presence of protein L20
OGM58_08355	COG0211	Belongs to the bacterial ribosomal protein bL27 family
OGM58_08360	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
OGM58_08365	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
OGM58_08370	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
OGM58_08375	COG2217	Heavy metal translocating P-type atpase
OGM58_08380	COG1293	RNA-binding protein homologous to eukaryotic snRNP
OGM58_08385	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
OGM58_08390	COG1561	YicC-like family, N-terminal region
OGM58_08400	COG0194	GDP metabolic process
OGM58_08405	COG1758	RNA polymerase activity
OGM58_08410	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
OGM58_08415	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
OGM58_08420	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
OGM58_08425	COG0242	peptide deformylase activity
OGM58_08430	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
OGM58_08435	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
OGM58_08435	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
OGM58_08440	COG0820	rRNA (adenine-C2-)-methyltransferase activity
OGM58_08445	COG0631	protein serine/threonine phosphatase activity
OGM58_08450	COG0515	serine threonine protein kinase
OGM58_08450	COG2815	serine threonine protein kinase
OGM58_08460	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
OGM58_08470	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
OGM58_08475	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
OGM58_08480	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
OGM58_08485	COG0402	S-adenosylhomocysteine deaminase activity
OGM58_08505	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
OGM58_08510	COG2996	Protein conserved in bacteria
OGM58_08515	COG0799	negative regulation of ribosome biogenesis
OGM58_08520	COG1316	TRANSCRIPTIONal
OGM58_08525	COG1713	HD superfamily hydrolase involved in NAD metabolism
OGM58_08530	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
OGM58_08535	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
OGM58_08545	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
OGM58_08550	COG0793	Belongs to the peptidase S41A family
OGM58_08550	COG3409	Peptidoglycan-binding domain 1 protein
OGM58_08560	COG2177	Part of the ABC transporter FtsEX involved in
OGM58_08565	COG2884	Cell division ATP-binding protein ftsE
OGM58_08570	COG3958	Transketolase
OGM58_08575	COG3959	Transketolase, thiamine diphosphate binding domain
OGM58_08590	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
OGM58_08595	COG0653	protein targeting
OGM58_08600	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
OGM58_08605	COG1278	Cold shock
OGM58_08615	COG0765	amino acid transport
OGM58_08620	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
OGM58_08625	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
OGM58_08625	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
OGM58_08630	COG4956	integral membrane protein (PIN domain superfamily)
OGM58_08635	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
OGM58_08640	COG0542	response to heat
OGM58_08650	COG3880	PFAM UvrB UvrC protein
OGM58_08655	COG4463	regulation of RNA biosynthetic process
OGM58_08665	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
OGM58_08670	COG1058	Belongs to the CinA family
OGM58_08670	COG1546	Belongs to the CinA family
OGM58_08675	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
OGM58_08685	COG1674	ftsk spoiiie
OGM58_08690	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
OGM58_08700	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
OGM58_08705	COG0124	histidyl-tRNA synthetase
OGM58_08710	COG0735	belongs to the Fur family
OGM58_08715	COG0628	permease
OGM58_08720	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OGM58_08725	COG1490	D-aminoacyl-tRNA deacylase activity
OGM58_08730	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
OGM58_08735	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
OGM58_08735	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
OGM58_08765	COG0497	DNA recombination
OGM58_08775	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
OGM58_08780	COG0072	phenylalanine-tRNA ligase activity
OGM58_08780	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OGM58_08785	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
OGM58_08800	COG0577	efflux transmembrane transporter activity
OGM58_08800	COG1136	(ABC) transporter
OGM58_08805	COG1136	(ABC) transporter
OGM58_08815	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
OGM58_08820	COG4475	Protein of unknown function (DUF436)
OGM58_08825	COG0698	ribose 5-phosphate isomerase
OGM58_08830	COG0009	L-threonylcarbamoyladenylate synthase
OGM58_08835	COG2890	protein-(glutamine-N5) methyltransferase activity
OGM58_08840	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
OGM58_08845	COG0254	rRNA binding
OGM58_08850	COG3118	belongs to the thioredoxin family
OGM58_08855	COG1530	ribonuclease E activity
OGM58_08870	COG0772	Belongs to the SEDS family
OGM58_08875	COG2894	cell division
OGM58_08880	COG0768	penicillin binding
OGM58_08895	COG1077	Cell shape determining protein MreB Mrl
OGM58_08925	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OGM58_08965	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
OGM58_08985	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
OGM58_08990	COG0291	Belongs to the bacterial ribosomal protein bL35 family
OGM58_08995	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
OGM58_09010	COG1285	pathogenesis
OGM58_09015	COG0765	amino acid transport
OGM58_09025	COG1210	Utp--glucose-1-phosphate uridylyltransferase
OGM58_09030	COG1132	(ABC) transporter
OGM58_09035	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
OGM58_09035	COG1240	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
OGM58_09040	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
OGM58_09050	COG0494	nUDIX hydrolase
OGM58_09055	COG0756	dUTP diphosphatase activity
OGM58_09060	COG1185	polyribonucleotide nucleotidyltransferase activity
OGM58_09075	COG4120	Belongs to the binding-protein-dependent transport system permease family
OGM58_09090	COG0333	Belongs to the bacterial ribosomal protein bL32 family
OGM58_09095	COG0322	excinuclease ABC activity
OGM58_09105	COG0556	nucleotide-excision repair
OGM58_09110	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
OGM58_09115	COG0776	regulation of translation
OGM58_09120	COG3956	TIGRFAM MazG family protein
OGM58_09125	COG0084	hydrolase, TatD family'
OGM58_09130	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OGM58_09130	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OGM58_09135	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
OGM58_09140	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
OGM58_09145	COG1774	PSP1 C-terminal conserved region
OGM58_09150	COG0470	DNA polymerase III
OGM58_09160	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
OGM58_09165	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
OGM58_09170	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
OGM58_09170	COG0758	DNA mediated transformation
OGM58_09175	COG0606	chelatase, subunit chli
OGM58_09180	COG0792	nuclease activity
OGM58_09190	COG1528	Iron-storage protein
OGM58_09195	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
OGM58_09200	COG0113	porphobilinogen synthase activity
OGM58_09215	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
OGM58_09220	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
OGM58_09220	COG1648	precorrin-2 dehydrogenase activity
OGM58_09235	COG0306	phosphate transporter
OGM58_09250	COG0571	ribonuclease III activity
OGM58_09255	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
OGM58_09260	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
OGM58_09270	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
OGM58_09275	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
OGM58_09280	COG0416	fatty acid biosynthetic process
OGM58_09285	COG1349	DNA-binding transcription factor activity
OGM58_09285	COG2050	protein possibly involved in aromatic compounds catabolism
OGM58_09295	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
OGM58_09300	COG0284	orotidine-5'-phosphate decarboxylase activity
OGM58_09310	COG4632	Exopolysaccharide biosynthesis protein
OGM58_09310	COG5434	Belongs to the glycosyl hydrolase 28 family
OGM58_09320	COG0860	N-Acetylmuramoyl-L-alanine amidase
OGM58_09350	COG0557	exoribonuclease II activity
OGM58_09370	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
OGM58_09375	COG0215	cysteine-tRNA ligase activity
OGM58_09380	COG0347	Belongs to the P(II) protein family
OGM58_09385	COG0004	ammonium transporteR
OGM58_09405	COG0285	dihydrofolate synthase activity
OGM58_09410	COG0525	valine-tRNA ligase activity
OGM58_09425	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
OGM58_09430	COG0180	Tryptophanyl-tRNA synthetase
OGM58_09435	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
OGM58_09445	COG0616	signal peptide processing
OGM58_09450	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
OGM58_09455	COG1687	branched-chain amino acid
OGM58_09475	COG1268	BioY protein
OGM58_09480	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
OGM58_09480	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
OGM58_09485	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
OGM58_09490	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
OGM58_09510	COG0812	UDP-N-acetylmuramate dehydrogenase activity
OGM58_09515	COG1879	ABC-type sugar transport system periplasmic component
OGM58_09520	COG1172	Belongs to the binding-protein-dependent transport system permease family
OGM58_09525	COG1129	ABC transporter
OGM58_09530	COG1869	D-ribose catabolic process
OGM58_09535	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OGM58_09550	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
OGM58_09555	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
OGM58_09560	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
OGM58_09570	COG0488	(ABC) transporter
OGM58_09585	COG0166	Belongs to the GPI family
OGM58_09660	COG0174	glutamine synthetase
OGM58_09665	COG0174	glutamine synthetase
OGM58_09680	COG0537	adenosine 5'-monophosphoramidase activity
OGM58_09685	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
OGM58_09690	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
OGM58_09695	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
OGM58_09705	COG1862	Preprotein translocase
OGM58_09710	COG0343	queuine tRNA-ribosyltransferase activity
OGM58_09720	COG2385	sporulation resulting in formation of a cellular spore
OGM58_09730	COG2255	four-way junction helicase activity
OGM58_09735	COG0632	four-way junction helicase activity
OGM58_09740	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
OGM58_09755	COG2086	electron transfer activity
OGM58_09775	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
OGM58_09795	COG1760	l-serine dehydratase
OGM58_09800	COG1760	l-serine dehydratase
OGM58_09820	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
OGM58_09830	COG2720	vancomycin resistance protein
OGM58_09845	COG2183	response to ionizing radiation
OGM58_09855	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
OGM58_09860	COG0742	ribosomal rna small subunit methyltransferase
OGM58_09865	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
OGM58_09870	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
OGM58_09875	COG1160	GTP binding
OGM58_09880	COG0539	negative regulation of cytoplasmic translation
OGM58_09880	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
OGM58_09895	COG2081	HI0933 family
OGM58_09900	COG1187	pseudouridine synthase activity
OGM58_09905	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
OGM58_09915	COG1982	Orn Lys Arg decarboxylase major
OGM58_09920	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
OGM58_09945	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
OGM58_09960	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
OGM58_09965	COG1420	regulation of RNA biosynthetic process
OGM58_09970	COG0471	metal ion transport
OGM58_09975	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
OGM58_09990	COG4221	oxidoreductase activity
OGM58_10005	COG1757	Na H antiporter
OGM58_10035	COG0789	Transcriptional regulator
OGM58_10040	COG2033	superoxide reductase activity
OGM58_10050	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
OGM58_10055	COG3328	transposase activity
OGM58_10060	COG0110	maltose O-acetyltransferase activity
OGM58_10090	COG0183	Belongs to the thiolase family
OGM58_10100	COG1268	BioY protein
OGM58_10105	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
OGM58_10110	COG0751	glycine-tRNA ligase activity
OGM58_10115	COG0752	glycyl-tRNA synthetase alpha subunit
OGM58_10140	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
OGM58_10145	COG1733	regulation of RNA biosynthetic process
OGM58_10155	COG0822	iron-sulfur transferase activity
OGM58_10160	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
OGM58_10170	COG0719	Fe-S assembly protein
OGM58_10175	COG0396	ATPase activity
OGM58_10185	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OGM58_10190	COG0586	Pfam SNARE associated Golgi protein
OGM58_10195	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
OGM58_10200	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
OGM58_10240	COG0772	Belongs to the SEDS family
OGM58_10245	COG0220	tRNA (guanine-N7-)-methyltransferase activity
OGM58_10250	COG2194	sulfuric ester hydrolase activity
OGM58_10260	COG3830	Belongs to the UPF0237 family
OGM58_10265	COG0708	Exodeoxyribonuclease III
OGM58_10270	COG5002	protein histidine kinase activity
OGM58_10275	COG0745	RESPONSE REGULATOR receiver
OGM58_10280	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
OGM58_10285	COG0561	phosphatase activity
OGM58_10290	COG0697	spore germination
OGM58_10295	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
OGM58_10300	COG0564	pseudouridine synthase activity
OGM58_10320	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OGM58_10340	COG1982	Orn Lys Arg decarboxylase major
OGM58_10375	COG5002	protein histidine kinase activity
OGM58_10380	COG0745	RESPONSE REGULATOR receiver
OGM58_10385	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
OGM58_10390	COG0581	inorganic phosphate transmembrane transporter activity
OGM58_10395	COG0573	inorganic phosphate transmembrane transporter activity
OGM58_10400	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
OGM58_10405	COG0151	Belongs to the GarS family
OGM58_10410	COG0138	bifunctional purine biosynthesis protein purh
OGM58_10415	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
OGM58_10420	COG0436	Aminotransferase
OGM58_10425	COG1473	amidohydrolase
OGM58_10430	COG2171	N-acyltransferase activity
OGM58_10435	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
OGM58_10440	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
OGM58_10445	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
OGM58_10450	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
OGM58_10460	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
OGM58_10480	COG1126	abc transporter atp-binding protein
OGM58_10490	COG0765	amino acid transport
OGM58_10510	COG4948	Mandelate Racemase Muconate Lactonizing
OGM58_10515	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
OGM58_10520	COG4948	Mandelate Racemase Muconate Lactonizing
OGM58_10525	COG2271	Major facilitator Superfamily
OGM58_10530	COG2271	Major facilitator Superfamily
OGM58_10550	COG0589	response to stress
OGM58_10555	COG0101	tRNA pseudouridine synthase activity
OGM58_10570	COG1362	aminopeptidase activity
OGM58_10575	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
OGM58_10585	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
OGM58_10590	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
OGM58_10595	COG0385	Bile acid
OGM58_10625	COG1295	ribonuclease BN
OGM58_10630	COG1217	gtp-binding protein TYPA
OGM58_10635	COG2357	RelA SpoT domain protein
OGM58_10640	COG0745	RESPONSE REGULATOR receiver
OGM58_10650	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
OGM58_10665	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
OGM58_10670	COG0085	RNA polymerase activity
OGM58_10675	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
OGM58_10680	COG1970	mechanosensitive ion channel activity
OGM58_10690	COG1773	rubredoxin
OGM58_10705	COG1959	2 iron, 2 sulfur cluster binding
OGM58_10720	COG2910	NAD(P)H-binding
OGM58_10725	COG0217	transcriptional regulatory protein
OGM58_10730	COG4752	Belongs to the RNA methyltransferase TrmD family
OGM58_10735	COG0336	Belongs to the RNA methyltransferase TrmD family
OGM58_10740	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
OGM58_10750	COG1837	Belongs to the UPF0109 family
OGM58_10760	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
OGM58_10765	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
OGM58_10770	COG0165	Argininosuccinate lyase
OGM58_10775	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
OGM58_10775	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
OGM58_10780	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
OGM58_10820	COG1051	belongs to the nudix hydrolase family
OGM58_10850	COG0671	phosphoesterase, PA-phosphatase related
OGM58_10860	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
OGM58_10880	COG0516	GMP reductase activity
OGM58_10880	COG0517	IMP dehydrogenase activity