locus-tag	class	description
FKW77_000032	COG0473	3-isopropylmalate dehydrogenase activity
FKW77_000142	COG0489	protein tyrosine kinase activity
FKW77_000183	COG2175	clavaminate synthase activity
FKW77_000237	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FKW77_000297	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FKW77_000358	COG4251	negative regulation of phosphorylation
FKW77_000403	COG1960	acyl-CoA dehydrogenase activity
FKW77_000443	COG3142	Participates in the control of copper homeostasis
FKW77_000457	COG0183	Belongs to the thiolase family
FKW77_000489	COG1028	Short-chain dehydrogenase reductase Sdr
FKW77_000635	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FKW77_000667	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FKW77_000693	COG0318	PFAM AMP-dependent synthetase and ligase
FKW77_000712	COG0484	heat shock protein binding
FKW77_000717	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FKW77_000718	COG0515	serine threonine protein kinase
FKW77_000718	COG2815	serine threonine protein kinase
FKW77_000725	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FKW77_000772	COG0460	homoserine dehydrogenase
FKW77_000772	COG0527	aspartate kinase activity
FKW77_000775	COG3345	alpha-galactosidase
FKW77_000883	COG0401	homolog of Blt101
FKW77_000912	COG2815	serine threonine protein kinase
FKW77_000912	COG0515	serine threonine protein kinase
FKW77_000942	COG0515	serine threonine protein kinase
FKW77_000970	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
FKW77_001072	COG1902	pentaerythritol trinitrate reductase activity
FKW77_001234	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FKW77_001252	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FKW77_001253	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FKW77_001433	COG2226	methyltransferase
FKW77_001451	COG2814	Major facilitator Superfamily
FKW77_001476	COG0830	nickel cation binding
FKW77_001547	COG1953	Uracil, thiamine, allantoin
FKW77_001590	COG0542	response to heat
FKW77_001636	COG0515	serine threonine protein kinase
FKW77_001683	COG0784	Response regulator, receiver
FKW77_001683	COG2198	Histidine kinase
FKW77_001683	COG2205	protein histidine kinase activity
FKW77_001718	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FKW77_001821	COG0513	Belongs to the DEAD box helicase family
FKW77_001864	COG2890	protein-(glutamine-N5) methyltransferase activity
FKW77_002044	COG0484	heat shock protein binding
FKW77_002102	COG1024	Enoyl-CoA hydratase
FKW77_002200	COG0517	IMP dehydrogenase activity
FKW77_002200	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FKW77_002213	COG1741	Belongs to the pirin family
FKW77_002374	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
FKW77_002383	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FKW77_002470	COG0515	serine threonine protein kinase
FKW77_002472	COG2070	2-Nitropropane dioxygenase
FKW77_002527	COG0513	Belongs to the DEAD box helicase family
FKW77_002544	COG2130	NADP-dependent
FKW77_002548	COG1063	alcohol dehydrogenase
FKW77_002715	COG0156	8-amino-7-oxononanoate synthase activity
FKW77_002723	COG0154	amidase activity
FKW77_002790	COG3781	membrane
FKW77_002851	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FKW77_002865	COG0673	inositol 2-dehydrogenase activity
FKW77_002925	COG0167	dihydroorotate dehydrogenase activity
FKW77_002960	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FKW77_002961	COG0443	Heat shock 70 kDa protein
FKW77_002990	COG0484	heat shock protein binding
FKW77_003016	COG0625	glutathione transferase activity
FKW77_003017	COG0523	cobalamin synthesis protein
FKW77_003039	COG0829	nickel cation binding
FKW77_003051	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FKW77_003063	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FKW77_003107	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FKW77_003111	COG0588	phosphoglycerate mutase activity
FKW77_003253	COG0430	RNA-3'-phosphate cyclase activity
FKW77_003409	COG0724	RNA recognition motif
FKW77_003482	COG0571	ribonuclease III activity
FKW77_003486	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
FKW77_003595	COG3254	rhamnose metabolic process
FKW77_003619	COG2814	Major facilitator Superfamily
FKW77_003648	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FKW77_003686	COG0657	acetylesterase activity
FKW77_003807	COG4221	oxidoreductase activity
FKW77_004034	COG2226	methyltransferase
FKW77_004082	COG1785	Belongs to the alkaline phosphatase family
FKW77_004214	COG2815	serine threonine protein kinase
FKW77_004214	COG0515	serine threonine protein kinase
FKW77_004241	COG2072	flavoprotein involved in K transport
FKW77_004441	COG1028	Short-chain dehydrogenase reductase Sdr
FKW77_004489	COG1205	dead DEAH box helicase
FKW77_004489	COG1111	helicase
FKW77_004553	COG1643	Atp-dependent helicase
FKW77_004600	COG1028	Short-chain dehydrogenase reductase Sdr
FKW77_004714	COG2072	flavoprotein involved in K transport
FKW77_004921	COG0513	Belongs to the DEAD box helicase family
FKW77_004941	COG0617	tRNA 3'-terminal CCA addition
FKW77_005152	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FKW77_005212	COG2267	carboxylic ester hydrolase activity
FKW77_005220	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FKW77_005299	COG0006	proline dipeptidase activity
FKW77_005316	COG3239	Fatty acid desaturase
FKW77_005373	COG0011	TIGRFAM Protein of
FKW77_005428	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
FKW77_005478	COG0542	response to heat
FKW77_005554	COG0513	Belongs to the DEAD box helicase family
FKW77_005612	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FKW77_005650	COG0513	Belongs to the DEAD box helicase family
FKW77_005723	COG1064	alcohol dehydrogenase
FKW77_005761	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FKW77_005780	COG0085	RNA polymerase activity
FKW77_005807	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FKW77_005921	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FKW77_005954	COG3453	Protein conserved in bacteria
FKW77_005954	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FKW77_006093	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FKW77_006117	COG0259	pyridoxamine-phosphate oxidase activity
FKW77_006124	COG0205	6-phosphofructokinase activity
FKW77_006217	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FKW77_006242	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FKW77_006286	COG0667	Aldo Keto reductase
FKW77_006345	COG2815	serine threonine protein kinase
FKW77_006345	COG0515	serine threonine protein kinase
FKW77_006350	COG1657	PFAM Prenyltransferase squalene oxidase
FKW77_006353	COG0483	inositol monophosphate 1-phosphatase activity
FKW77_006368	COG5441	Belongs to the UPF0261 family
FKW77_006493	COG2132	Multicopper oxidase
FKW77_006641	COG0656	L-ascorbic acid biosynthetic process
FKW77_006697	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
FKW77_006834	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FKW77_006834	COG1017	nitric oxide dioxygenase activity
FKW77_006874	COG0167	dihydroorotate dehydrogenase activity
FKW77_006898	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FKW77_006936	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FKW77_006961	COG1643	Atp-dependent helicase
FKW77_007014	COG0625	glutathione transferase activity
FKW77_007016	COG0724	RNA recognition motif
FKW77_007038	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FKW77_007043	COG0071	Belongs to the small heat shock protein (HSP20) family
FKW77_007053	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FKW77_007117	COG0515	serine threonine protein kinase
FKW77_007117	COG2815	serine threonine protein kinase
FKW77_007121	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FKW77_007123	COG3118	belongs to the thioredoxin family
FKW77_007387	COG2815	serine threonine protein kinase
FKW77_007387	COG0515	serine threonine protein kinase
FKW77_007395	COG0483	inositol monophosphate 1-phosphatase activity
FKW77_007438	COG2070	2-Nitropropane dioxygenase
FKW77_007451	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FKW77_007497	COG1024	Enoyl-CoA hydratase
FKW77_007504	COG1418	mRNA catabolic process
FKW77_007507	COG1643	Atp-dependent helicase
FKW77_007594	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FKW77_007594	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FKW77_007728	COG4221	oxidoreductase activity
FKW77_007742	COG0483	inositol monophosphate 1-phosphatase activity
FKW77_007792	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
FKW77_007805	COG1643	Atp-dependent helicase
FKW77_007848	COG0604	alcohol dehydrogenase
FKW77_007875	COG0489	protein tyrosine kinase activity
FKW77_007906	COG0477	Major facilitator Superfamily
FKW77_007934	COG1764	response to oxidative stress
FKW77_007984	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FKW77_008168	COG4221	oxidoreductase activity
FKW77_008232	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FKW77_008246	COG0513	Belongs to the DEAD box helicase family
FKW77_008309	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FKW77_008346	COG1335	isochorismatase
FKW77_008347	COG0210	DNA helicase
FKW77_008352	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FKW77_008363	COG1028	Short-chain dehydrogenase reductase Sdr
FKW77_008386	COG2040	homocysteine
FKW77_008444	COG0572	uridine kinase
FKW77_008455	COG2154	pterin-4-alpha-carbinolamine dehydratase
FKW77_008462	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FKW77_008468	COG0084	hydrolase, TatD family'
FKW77_008537	COG1024	Enoyl-CoA hydratase
FKW77_008537	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FKW77_008550	COG0123	including yeast histone deacetylase and acetoin utilization protein
FKW77_008560	COG1185	polyribonucleotide nucleotidyltransferase activity
FKW77_008621	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FKW77_008623	COG1028	Short-chain dehydrogenase reductase Sdr
FKW77_008737	COG0316	Belongs to the HesB IscA family
FKW77_008777	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FKW77_008814	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FKW77_008822	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FKW77_008964	COG2351	hydroxyisourate hydrolase activity
FKW77_008967	COG0724	RNA recognition motif
FKW77_009041	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FKW77_009134	COG2140	Oxalate decarboxylase
FKW77_009169	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FKW77_009173	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FKW77_009173	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FKW77_009192	COG0667	Aldo Keto reductase
FKW77_009226	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FKW77_009328	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
FKW77_009418	COG1028	Short-chain dehydrogenase reductase Sdr
FKW77_009432	COG1063	alcohol dehydrogenase
FKW77_009525	COG0129	dihydroxy-acid dehydratase activity
FKW77_009527	COG1028	Short-chain dehydrogenase reductase Sdr
FKW77_009561	COG0571	ribonuclease III activity
FKW77_009632	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FKW77_009657	COG0484	heat shock protein binding
FKW77_009708	COG0484	heat shock protein binding
FKW77_009810	COG1185	polyribonucleotide nucleotidyltransferase activity
FKW77_009811	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FKW77_009824	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FKW77_009905	COG1643	Atp-dependent helicase
FKW77_009946	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FKW77_009961	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FKW77_009966	COG0515	serine threonine protein kinase
FKW77_010003	COG1250	3-hydroxyacyl-CoA dehydrogenase
FKW77_010012	COG0101	tRNA pseudouridine synthase activity
FKW77_010018	COG0009	L-threonylcarbamoyladenylate synthase
FKW77_010034	COG1960	acyl-CoA dehydrogenase activity
FKW77_010051	COG0071	Belongs to the small heat shock protein (HSP20) family
FKW77_010112	COG4221	oxidoreductase activity
FKW77_010143	COG1643	Atp-dependent helicase
FKW77_010216	COG0438	transferase activity, transferring glycosyl groups
FKW77_010305	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FKW77_010343	COG0515	serine threonine protein kinase
FKW77_010362	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FKW77_010400	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FKW77_010425	COG1028	Short-chain dehydrogenase reductase Sdr
FKW77_010455	COG2132	Multicopper oxidase
FKW77_010488	COG1610	YqeY-like protein
FKW77_010559	COG0017	Asparaginyl-tRNA synthetase
FKW77_010609	COG0515	serine threonine protein kinase
FKW77_010609	COG2815	serine threonine protein kinase
FKW77_010610	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FKW77_010642	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FKW77_010746	COG2515	1-aminocyclopropane-1-carboxylate deaminase
FKW77_010772	COG0300	oxidoreductase activity
FKW77_010787	COG2079	MmgE PrpD family protein
FKW77_010823	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
FKW77_010895	COG2217	Heavy metal translocating P-type atpase