locus-tag	class	description
KG892_00010	COG0084	hydrolase, TatD family'
KG892_00015	COG0776	regulation of translation
KG892_00020	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
KG892_00025	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KG892_00045	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KG892_00060	COG1793	dna ligase
KG892_00080	COG0357	Ribosomal RNA small subunit methyltransferase G
KG892_00090	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KG892_00095	COG0154	amidase activity
KG892_00105	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KG892_00115	COG0616	signal peptide processing
KG892_00150	COG1132	(ABC) transporter
KG892_00160	COG0510	thiamine kinase activity
KG892_00180	COG0456	acetyltransferase
KG892_00205	COG3173	Aminoglycoside phosphotransferase
KG892_00220	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
KG892_00225	COG1280	lysine exporter protein (LysE YggA)
KG892_00235	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KG892_00280	COG0254	rRNA binding
KG892_00285	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KG892_00290	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KG892_00300	COG1881	PFAM PEBP family protein
KG892_00305	COG0504	CTP synthase activity
KG892_00315	COG0513	Belongs to the DEAD box helicase family
KG892_00325	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KG892_00365	COG0288	reversible hydration of carbon dioxide
KG892_00375	COG0492	ferredoxin-NADP+ reductase activity
KG892_00385	COG1561	YicC-like family, N-terminal region
KG892_00390	COG0217	transcriptional regulatory protein
KG892_00395	COG2255	four-way junction helicase activity
KG892_00400	COG0772	Belongs to the SEDS family
KG892_00440	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KG892_00450	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
KG892_00485	COG0261	This protein binds to 23S rRNA in the presence of protein L20
KG892_00500	COG1335	isochorismatase
KG892_00510	COG0423	glycine-tRNA ligase activity
KG892_00515	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KG892_00530	COG1114	Component of the transport system for branched-chain amino acids
KG892_00570	COG1704	LemA family
KG892_00625	COG0860	N-Acetylmuramoyl-L-alanine amidase
KG892_00660	COG0698	ribose 5-phosphate isomerase
KG892_00665	COG0492	ferredoxin-NADP+ reductase activity
KG892_00680	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
KG892_00690	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
KG892_00695	COG0772	Belongs to the SEDS family
KG892_00705	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KG892_00710	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KG892_00740	COG0359	binds to the 23S rRNA
KG892_00745	COG0305	Participates in initiation and elongation during chromosome replication
KG892_00750	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
KG892_00760	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KG892_00770	COG0442	prolyl-tRNA aminoacylation
KG892_00795	COG1692	metallophosphoesterase
KG892_00800	COG1418	mRNA catabolic process
KG892_00815	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KG892_00820	COG0291	Belongs to the bacterial ribosomal protein bL35 family
KG892_00825	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KG892_00830	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
KG892_00835	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KG892_00930	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KG892_00935	COG0443	Heat shock 70 kDa protein
KG892_00965	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
KG892_00975	COG3202	ADP transmembrane transporter activity
KG892_00985	COG0052	Belongs to the universal ribosomal protein uS2 family
KG892_01000	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KG892_01005	COG1160	GTP binding
KG892_01035	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KG892_01070	COG0617	tRNA 3'-terminal CCA addition
KG892_01105	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KG892_01110	COG0227	Belongs to the bacterial ribosomal protein bL28 family
KG892_01115	COG0268	Binds directly to 16S ribosomal RNA
KG892_01120	COG0768	penicillin binding
KG892_01150	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KG892_01165	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
KG892_01175	COG0594	ribonuclease P activity
KG892_01180	COG0230	Belongs to the bacterial ribosomal protein bL34 family
KG892_01185	COG0492	ferredoxin-NADP+ reductase activity
KG892_01215	COG0233	cytoplasmic translational termination
KG892_01220	COG0528	UMP kinase activity
KG892_01225	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KG892_01230	COG0018	arginyl-trna synthetase
KG892_01250	COG0629	single-stranded DNA binding
KG892_01290	COG0481	GTPase activity
KG892_01310	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KG892_01330	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KG892_01340	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KG892_01360	COG1968	undecaprenyl-diphosphatase activity
KG892_01365	COG1674	ftsk spoiiie
KG892_01370	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KG892_01375	COG0275	rRNA processing
KG892_01380	COG2088	sporulation resulting in formation of a cellular spore
KG892_01400	COG0424	maF-like protein
KG892_01420	COG0789	Transcriptional regulator
KG892_01435	COG0012	GTP binding
KG892_01445	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
KG892_01450	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
KG892_01450	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
KG892_01455	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
KG892_01490	COG0793	Belongs to the peptidase S41A family
KG892_01505	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KG892_01510	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
KG892_01535	COG0187	DNA topoisomerase II activity
KG892_01545	COG0037	tRNA processing
KG892_01645	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KG892_01650	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KG892_01650	COG1321	iron dependent repressor
KG892_01655	COG1121	(ABC) transporter
KG892_01660	COG0803	Belongs to the bacterial solute-binding protein 9 family
KG892_01665	COG1131	(ABC) transporter
KG892_01680	COG4555	ABC transporter
KG892_01690	COG0484	heat shock protein binding
KG892_01695	COG0484	heat shock protein binding
KG892_01715	COG0822	iron-sulfur transferase activity
KG892_01745	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KG892_01750	COG0719	Fe-S assembly protein
KG892_01760	COG0396	ATPase activity
KG892_01775	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KG892_01790	COG0776	regulation of translation
KG892_01830	COG0464	growth
KG892_01835	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KG892_01845	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KG892_01845	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KG892_01855	COG1177	transmembrane transport
KG892_01860	COG1176	ABC-type spermidine putrescine transport system, permease component I
KG892_01865	COG3842	ATPase activity
KG892_01900	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KG892_01905	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KG892_01915	COG0531	amino acid
KG892_01925	COG0828	Belongs to the bacterial ribosomal protein bS21 family
KG892_01965	COG0356	it plays a direct role in the translocation of protons across the membrane
KG892_01995	COG0318	PFAM AMP-dependent synthetase and ligase
KG892_02005	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KG892_02015	COG2723	6-phospho-beta-galactosidase activity
KG892_02055	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KG892_02070	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KG892_02105	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KG892_02115	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KG892_02135	COG1611	Belongs to the LOG family
KG892_02145	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
KG892_02170	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KG892_02210	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
KG892_02215	COG0072	phenylalanine-tRNA ligase activity
KG892_02215	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KG892_02220	COG1980	fructose-bisphosphate aldolase activity
KG892_02235	COG1131	(ABC) transporter
KG892_02260	COG1054	Belongs to the UPF0176 family
KG892_02265	COG0812	UDP-N-acetylmuramate dehydrogenase activity
KG892_02290	COG0343	queuine tRNA-ribosyltransferase activity
KG892_02295	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KG892_02315	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KG892_02340	COG0445	tRNA wobble uridine modification
KG892_02360	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
KG892_02370	COG0358	DNA primase activity
KG892_02405	COG1215	transferase activity, transferring glycosyl groups
KG892_02410	COG0275	rRNA processing
KG892_02445	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KG892_02505	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
KG892_02580	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
KG892_02585	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KG892_02585	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KG892_02590	COG0211	Belongs to the bacterial ribosomal protein bL27 family
KG892_02605	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KG892_02605	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KG892_02615	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KG892_02625	COG2226	methyltransferase
KG892_02630	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
KG892_02635	COG1181	Belongs to the D-alanine--D-alanine ligase family
KG892_02700	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
KG892_02730	COG1459	type II secretion system
KG892_02760	COG0736	holo-[acyl-carrier-protein] synthase activity
KG892_02785	COG5265	(ABC) transporter
KG892_02825	COG1136	(ABC) transporter
KG892_02830	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
KG892_02855	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
KG892_02880	COG1438	arginine binding
KG892_02890	COG0765	amino acid transport
KG892_02895	COG1126	abc transporter atp-binding protein
KG892_02905	COG0739	heme binding
KG892_02910	COG2515	1-aminocyclopropane-1-carboxylate deaminase
KG892_02915	COG0322	excinuclease ABC activity
KG892_02930	COG0542	response to heat
KG892_02950	COG0149	triose-phosphate isomerase activity
KG892_02960	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
KG892_02965	COG1127	ABC transporter
KG892_03010	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
KG892_03030	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
KG892_03035	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
KG892_03040	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
KG892_03045	COG0195	Participates in both transcription termination and antitermination
KG892_03050	COG1573	uracil-dna glycosylase
KG892_03070	COG0612	Peptidase, M16
KG892_03100	COG0415	Belongs to the DNA photolyase family
KG892_03125	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
KG892_03155	COG1530	ribonuclease E activity
KG892_03210	COG1515	deoxyribonuclease V activity
KG892_03225	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KG892_03255	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
KG892_03275	COG0632	four-way junction helicase activity
KG892_03285	COG3177	Filamentation induced by cAMP protein fic
KG892_03290	COG1115	amino acid carrier protein
KG892_03315	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
KG892_03320	COG0525	valine-tRNA ligase activity
KG892_03405	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KG892_03425	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KG892_03430	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KG892_03445	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KG892_03460	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KG892_03470	COG0693	protein deglycase activity
KG892_03500	COG1496	oxidoreductase activity
KG892_03510	COG0653	protein targeting
KG892_03535	COG0124	histidyl-tRNA synthetase
KG892_03545	COG0575	Belongs to the CDS family
KG892_03560	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KG892_03595	COG0564	pseudouridine synthase activity
KG892_03600	COG2239	Acts as a magnesium transporter
KG892_03665	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
KG892_03675	COG2267	carboxylic ester hydrolase activity
KG892_03680	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KG892_03760	COG0552	protein localization to endoplasmic reticulum
KG892_03765	COG0552	protein localization to endoplasmic reticulum
KG892_03775	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KG892_03800	COG0360	Binds together with S18 to 16S ribosomal RNA
KG892_03805	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
KG892_03810	COG1217	gtp-binding protein TYPA
KG892_03815	COG0101	tRNA pseudouridine synthase activity
KG892_03875	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KG892_03905	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
KG892_03925	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KG892_03925	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KG892_03930	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KG892_03950	COG0166	Belongs to the GPI family
KG892_03965	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KG892_03970	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
KG892_04010	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
KG892_04015	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
KG892_04055	COG3959	Transketolase, thiamine diphosphate binding domain
KG892_04075	COG0697	spore germination
KG892_04080	COG0488	(ABC) transporter
KG892_04110	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KG892_04115	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KG892_04130	COG0539	negative regulation of cytoplasmic translation
KG892_04155	COG4112	unkown
KG892_04205	COG1793	dna ligase
KG892_04205	COG3285	dna ligase
KG892_04215	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KG892_04240	COG0556	nucleotide-excision repair
KG892_04245	COG0339	signal peptide processing
KG892_04275	COG3264	Mechanosensitive ion channel
KG892_04275	COG1511	domain protein
KG892_04325	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KG892_04360	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
KG892_04400	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
KG892_04410	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
KG892_04415	COG0459	protein refolding
KG892_04440	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KG892_04450	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
KG892_04480	COG0768	penicillin binding
KG892_04490	COG2515	1-aminocyclopropane-1-carboxylate deaminase
KG892_04510	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KG892_04515	COG0215	cysteine-tRNA ligase activity
KG892_04530	COG0670	Belongs to the BI1 family
KG892_04540	COG0537	adenosine 5'-monophosphoramidase activity
KG892_04560	COG1872	DUF167
KG892_04580	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KG892_04580	COG2169	Transcriptional regulator
KG892_04625	COG0009	L-threonylcarbamoyladenylate synthase
KG892_04630	COG0783	Belongs to the Dps family
KG892_04635	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KG892_04700	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
KG892_04710	COG0194	GDP metabolic process
KG892_04800	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KG892_04815	COG1435	thymidine kinase activity
KG892_04820	COG1187	pseudouridine synthase activity
KG892_04825	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KG892_04860	COG5487	UPF0391 membrane protein
KG892_04905	COG0250	Participates in transcription elongation, termination and antitermination
KG892_04910	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KG892_04915	COG0081	regulation of translation
KG892_04920	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
KG892_04930	COG0085	RNA polymerase activity
KG892_04945	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
KG892_04950	COG1185	polyribonucleotide nucleotidyltransferase activity
KG892_04955	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
KG892_04965	COG0789	Transcriptional regulator
KG892_05035	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KG892_05080	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KG892_05085	COG0228	four-way junction DNA binding
KG892_05090	COG1837	Belongs to the UPF0109 family
KG892_05095	COG4752	Belongs to the RNA methyltransferase TrmD family
KG892_05095	COG0336	Belongs to the RNA methyltransferase TrmD family
KG892_05110	COG1472	Belongs to the glycosyl hydrolase 3 family
KG892_05130	COG2816	NAD+ diphosphatase activity
KG892_05145	COG1132	(ABC) transporter
KG892_05155	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KG892_05210	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KG892_05210	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KG892_05220	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
KG892_05230	COG0706	membrane insertase activity
KG892_05235	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KG892_05240	COG0006	proline dipeptidase activity
KG892_05275	COG0750	zinc metalloprotease
KG892_05285	COG0049	tRNA binding
KG892_05290	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KG892_05300	COG0051	transcription antitermination factor activity, RNA binding
KG892_05305	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
KG892_05310	COG0088	Forms part of the polypeptide exit tunnel
KG892_05315	COG0089	rRNA binding
KG892_05320	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
KG892_05325	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
KG892_05330	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
KG892_05335	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
KG892_05350	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
KG892_05355	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
KG892_05370	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KG892_05375	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
KG892_05380	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
KG892_05385	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
KG892_05390	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
KG892_05395	COG0200	Binds to the 23S rRNA
KG892_05400	COG0201	protein transport
KG892_05405	COG0563	adenylate kinase activity
KG892_05415	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
KG892_05420	COG0257	Belongs to the bacterial ribosomal protein bL36 family
KG892_05425	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
KG892_05430	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
KG892_05435	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
KG892_05440	COG0202	RNA polymerase activity
KG892_05445	COG0203	ribosomal protein L17
KG892_05460	COG0419	ATPase involved in DNA repair
KG892_05470	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
KG892_05525	COG2385	sporulation resulting in formation of a cellular spore
KG892_05535	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family