locus-tag	class	description
LW808_000005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
LW808_000010	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
LW808_000010	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
LW808_000015	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LW808_000020	COG0105	UTP biosynthetic process
LW808_000030	COG0124	histidyl-tRNA synthetase
LW808_000040	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
LW808_000045	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
LW808_000050	COG1160	GTP binding
LW808_000055	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
LW808_000060	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
LW808_000065	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
LW808_000070	COG0149	triose-phosphate isomerase activity
LW808_000080	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LW808_000085	COG0343	queuine tRNA-ribosyltransferase activity
LW808_000095	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
LW808_000100	COG0563	adenylate kinase activity
LW808_000105	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
LW808_000130	COG4974	Belongs to the 'phage' integrase family
LW808_000150	COG2165	general secretion pathway protein
LW808_000160	COG0714	Associated with various cellular activities
LW808_000165	COG2255	four-way junction helicase activity
LW808_000175	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
LW808_000180	COG0745	RESPONSE REGULATOR receiver
LW808_000185	COG1635	Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur
LW808_000190	COG0482	sulfurtransferase activity
LW808_000205	COG1426	Protein conserved in bacteria
LW808_000215	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LW808_000220	COG0154	amidase activity
LW808_000225	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LW808_000230	COG1040	competence protein
LW808_000240	COG1640	4-alpha-glucanotransferase
LW808_000255	COG0101	tRNA pseudouridine synthase activity
LW808_000260	COG0681	Belongs to the peptidase S26 family
LW808_000265	COG0006	proline dipeptidase activity
LW808_000300	COG1183	phosphatidylcholine synthase activity
LW808_000305	COG0564	pseudouridine synthase activity
LW808_000310	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LW808_000365	COG4789	Type iii secretion
LW808_000385	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
LW808_000415	COG1194	a g-specific adenine glycosylase
LW808_000430	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
LW808_000435	COG0470	DNA polymerase III
LW808_000465	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LW808_000480	COG2249	NAD(P)H dehydrogenase (quinone) activity
LW808_000485	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
LW808_000510	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LW808_000515	COG0227	Belongs to the bacterial ribosomal protein bL28 family
LW808_000520	COG1185	polyribonucleotide nucleotidyltransferase activity
LW808_000525	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
LW808_000530	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
LW808_000535	COG0442	prolyl-tRNA aminoacylation
LW808_000540	COG0525	valine-tRNA ligase activity
LW808_000565	COG0653	protein targeting
LW808_000580	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
LW808_000585	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
LW808_000590	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
LW808_000590	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
LW808_000595	COG1519	Transferase
LW808_000595	COG0220	tRNA (guanine-N7-)-methyltransferase activity
LW808_000600	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LW808_000605	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
LW808_000610	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
LW808_000615	COG1181	Belongs to the D-alanine--D-alanine ligase family
LW808_000620	COG1530	ribonuclease E activity
LW808_000625	COG0772	Belongs to the SEDS family
LW808_000630	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LW808_000635	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
LW808_000645	COG0356	it plays a direct role in the translocation of protons across the membrane
LW808_000675	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LW808_000680	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LW808_000690	COG0528	UMP kinase activity
LW808_000705	COG2056	Na+-H+ antiporter family
LW808_000710	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LW808_000715	COG2056	Na+-H+ antiporter family
LW808_000745	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
LW808_000765	COG1994	Peptidase M50
LW808_000795	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
LW808_000815	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LW808_000840	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
LW808_000850	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LW808_000860	COG1450	Type ii and iii secretion system protein
LW808_000865	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
LW808_000875	COG1132	(ABC) transporter
LW808_000885	COG2264	protein methyltransferase activity
LW808_000890	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
LW808_000905	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LW808_000910	COG0211	Belongs to the bacterial ribosomal protein bL27 family
LW808_000915	COG0261	This protein binds to 23S rRNA in the presence of protein L20
LW808_000925	COG1663	tetraacyldisaccharide 4'-kinase activity
LW808_000950	COG0592	DNA-directed DNA polymerase activity
LW808_000960	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
LW808_000965	COG0166	Belongs to the GPI family
LW808_000970	COG0828	Belongs to the bacterial ribosomal protein bS21 family
LW808_000990	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
LW808_000995	COG0267	Belongs to the bacterial ribosomal protein bL33 family
LW808_001005	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
LW808_001005	COG0758	DNA mediated transformation
LW808_001010	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
LW808_001015	COG0423	glycine-tRNA ligase activity
LW808_001030	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LW808_001035	COG0012	GTP binding
LW808_001050	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
LW808_001080	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
LW808_001085	COG0445	tRNA wobble uridine modification
LW808_001090	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
LW808_001105	COG0228	four-way junction DNA binding
LW808_001120	COG0859	PFAM glycosyl transferase family 9
LW808_001125	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LW808_001130	COG0084	hydrolase, TatD family'
LW808_001135	COG1968	undecaprenyl-diphosphatase activity
LW808_001160	COG1317	bacterial-type flagellum organization
LW808_001180	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LW808_001195	COG1758	RNA polymerase activity
LW808_001200	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
LW808_001210	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LW808_001215	COG0772	Belongs to the SEDS family
LW808_001220	COG0741	lytic transglycosylase activity
LW808_001220	COG1388	LysM domain
LW808_001225	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
LW808_001240	COG0765	amino acid transport
LW808_001245	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
LW808_001250	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
LW808_001260	COG4942	peptidase
LW808_001275	COG0501	Belongs to the peptidase M48B family
LW808_001280	COG0318	PFAM AMP-dependent synthetase and ligase
LW808_001285	COG4191	Histidine kinase
LW808_001290	COG0203	ribosomal protein L17
LW808_001295	COG0202	RNA polymerase activity
LW808_001300	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
LW808_001305	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
LW808_001310	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
LW808_001315	COG0024	Methionine aminopeptidase
LW808_001325	COG0200	Binds to the 23S rRNA
LW808_001330	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
LW808_001335	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
LW808_001340	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
LW808_001345	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
LW808_001350	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LW808_001355	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
LW808_001365	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
LW808_001370	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
LW808_001375	COG0255	Belongs to the universal ribosomal protein uL29 family
LW808_001380	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
LW808_001385	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
LW808_001390	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
LW808_001395	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
LW808_001400	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
LW808_001405	COG0089	rRNA binding
LW808_001410	COG0088	Forms part of the polypeptide exit tunnel
LW808_001415	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
LW808_001420	COG0051	transcription antitermination factor activity, RNA binding
LW808_001425	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
LW808_001430	COG0049	tRNA binding
LW808_001435	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
LW808_001445	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LW808_001450	COG0085	RNA polymerase activity
LW808_001455	COG0222	ribosome binding
LW808_001460	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
LW808_001465	COG0081	regulation of translation
LW808_001470	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
LW808_001475	COG0250	Participates in transcription elongation, termination and antitermination
LW808_001480	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
LW808_001490	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
LW808_001500	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LW808_001515	COG0210	DNA helicase
LW808_001520	COG0196	riboflavin kinase activity
LW808_001525	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
LW808_001530	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
LW808_001535	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
LW808_001540	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
LW808_001545	COG0052	Belongs to the universal ribosomal protein uS2 family
LW808_001550	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
LW808_001555	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
LW808_001560	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
LW808_001565	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
LW808_001570	COG0110	maltose O-acetyltransferase activity
LW808_001575	COG2239	Acts as a magnesium transporter
LW808_001585	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
LW808_001590	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
LW808_001600	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
LW808_001605	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LW808_001630	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
LW808_001660	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LW808_001670	COG0194	GDP metabolic process
LW808_001675	COG0617	tRNA 3'-terminal CCA addition
LW808_001685	COG2165	general secretion pathway protein
LW808_001700	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
LW808_001705	COG0481	GTPase activity
LW808_001710	COG0439	Biotin carboxylase
LW808_001715	COG0511	ligase activity, forming carbon-carbon bonds
LW808_001725	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LW808_001815	COG0416	fatty acid biosynthetic process
LW808_001830	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
LW808_001835	COG0193	aminoacyl-tRNA hydrolase activity
LW808_001840	COG0360	Binds together with S18 to 16S ribosomal RNA
LW808_001845	COG0629	single-stranded DNA binding
LW808_001850	COG0359	binds to the 23S rRNA
LW808_001855	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
LW808_001970	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
LW808_001985	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
LW808_001985	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
LW808_001985	COG1013	pyruvate-flavodoxin oxidoreductase activity
LW808_001985	COG0674	pyruvate-flavodoxin oxidoreductase activity
LW808_002000	COG0688	phosphatidylethanolamine metabolic process
LW808_002010	COG0693	protein deglycase activity
LW808_002020	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
LW808_002095	COG0396	ATPase activity
LW808_002100	COG0719	Fe-S assembly protein
LW808_002120	COG0443	Heat shock 70 kDa protein
LW808_002125	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
LW808_002130	COG0459	protein refolding
LW808_002135	COG0305	Participates in initiation and elongation during chromosome replication
LW808_002140	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LW808_002170	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
LW808_002180	COG0708	Exodeoxyribonuclease III
LW808_002190	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
LW808_002200	COG0436	Aminotransferase
LW808_002250	COG0268	Binds directly to 16S ribosomal RNA
LW808_002270	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
LW808_002275	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LW808_002280	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
LW808_002295	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LW808_002300	COG1363	Peptidase, m42
LW808_002360	COG1595	DNA-templated transcription, initiation
LW808_002370	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LW808_002400	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
LW808_002415	COG1830	Aldolase
LW808_002420	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
LW808_002425	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LW808_002445	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
LW808_002450	COG0336	Belongs to the RNA methyltransferase TrmD family
LW808_002455	COG0335	large ribosomal subunit rRNA binding
LW808_002465	COG2890	protein-(glutamine-N5) methyltransferase activity
LW808_002470	COG4794	Type iii secretion
LW808_002475	COG4791	protein targeting
LW808_002480	COG4792	protein secretion
LW808_002490	COG2095	MarC family integral membrane protein
LW808_002495	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LW808_002515	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LW808_002520	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LW808_002525	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LW808_002545	COG1475	DNA binding
LW808_002550	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
LW808_002555	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
LW808_002560	COG0504	CTP synthase activity
LW808_002585	COG1127	ABC transporter
LW808_002590	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
LW808_002590	COG3008	intermembrane lipid transfer
LW808_002600	COG0148	phosphopyruvate hydratase activity
LW808_002610	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
LW808_002615	COG0814	amino acid
LW808_002625	COG0602	queuosine metabolic process
LW808_002640	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
LW808_002645	COG0291	Belongs to the bacterial ribosomal protein bL35 family
LW808_002650	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
LW808_002660	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
LW808_002675	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
LW808_002680	COG4790	Type iii secretion
LW808_002690	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
LW808_002690	COG3170	Tfp pilus assembly protein FimV
LW808_002695	COG1480	7TM receptor with intracellular HD hydrolase
LW808_002705	COG4591	ABC-type transport system involved in lipoprotein release permease component
LW808_002710	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LW808_002740	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LW808_002750	COG0776	regulation of translation
LW808_002760	COG0450	alkyl hydroperoxide reductase
LW808_002810	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
LW808_002815	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
LW808_002825	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
LW808_002830	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
LW808_002830	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
LW808_002835	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LW808_002840	COG0740	serine-type endopeptidase activity
LW808_002845	COG0544	peptidyl-prolyl cis-trans isomerase activity
LW808_002850	COG0531	amino acid
LW808_002855	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
LW808_002860	COG0552	protein localization to endoplasmic reticulum
LW808_002865	COG3842	ATPase activity
LW808_002875	COG0632	four-way junction helicase activity
LW808_002880	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
LW808_002885	COG0195	Participates in both transcription termination and antitermination
LW808_002890	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
LW808_002890	COG3064	Membrane
LW808_002895	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
LW808_002920	COG2877	3-deoxy-8-phosphooctulonate synthase activity
LW808_002925	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
LW808_002930	COG0257	Belongs to the bacterial ribosomal protein bL36 family
LW808_002940	COG0126	phosphoglycerate kinase activity
LW808_002950	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
LW808_002955	COG0484	heat shock protein binding
LW808_002965	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LW808_002990	COG3267	Type II secretory pathway component ExeA
LW808_002990	COG3409	Peptidoglycan-binding domain 1 protein
LW808_002995	COG0058	SHG alpha-glucan phosphorylase activity
LW808_003025	COG0542	response to heat
LW808_003035	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
LW808_003065	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
LW808_003070	COG0860	N-Acetylmuramoyl-L-alanine amidase
LW808_003070	COG1388	LysM domain
LW808_003075	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
LW808_003080	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LW808_003085	COG0537	adenosine 5'-monophosphoramidase activity
LW808_003095	COG0601	transmembrane transport
LW808_003100	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LW808_003100	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LW808_003105	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
LW808_003105	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
LW808_003110	COG2003	Belongs to the UPF0758 family
LW808_003130	COG0583	DNA-binding transcription factor activity
LW808_003145	COG0297	glycogen (starch) synthase activity
LW808_003245	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
LW808_003250	COG1136	(ABC) transporter
LW808_003260	COG0515	serine threonine protein kinase
LW808_003260	COG2815	serine threonine protein kinase
LW808_003275	COG2815	serine threonine protein kinase
LW808_003275	COG0515	serine threonine protein kinase
LW808_003285	COG2271	Major facilitator Superfamily
LW808_003290	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
LW808_003295	COG0009	L-threonylcarbamoyladenylate synthase
LW808_003300	COG0517	IMP dehydrogenase activity
LW808_003300	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
LW808_003305	COG1678	Uncharacterized ACR, COG1678
LW808_003310	COG0706	membrane insertase activity
LW808_003315	COG0217	transcriptional regulatory protein
LW808_003320	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
LW808_003330	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LW808_003335	COG0728	peptidoglycan biosynthetic process
LW808_003340	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LW808_003350	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
LW808_003365	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
LW808_003395	COG2204	response regulator
LW808_003415	COG0596	Alpha beta hydrolase
LW808_003420	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
LW808_003430	COG0825	malonyl-CoA metabolic process
LW808_003450	COG0500	methyltransferase
LW808_003470	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
LW808_003475	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
LW808_003520	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
LW808_003525	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
LW808_003530	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
LW808_003535	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
LW808_003545	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LW808_003580	COG0697	spore germination
LW808_003585	COG3118	belongs to the thioredoxin family
LW808_003590	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LW808_003590	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LW808_003595	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LW808_003605	COG0495	leucyl-tRNA aminoacylation
LW808_003615	COG0444	Belongs to the ABC transporter superfamily
LW808_003625	COG4589	Belongs to the CDS family
LW808_003630	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
LW808_003635	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LW808_003640	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LW808_003665	COG3869	Catalyzes the specific phosphorylation of arginine residues in
LW808_003685	COG0045	succinate-CoA ligase (ADP-forming) activity
LW808_003690	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
LW808_003695	COG0242	peptide deformylase activity
LW808_003700	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LW808_003720	COG0792	nuclease activity
LW808_003725	COG1573	uracil-dna glycosylase
LW808_003735	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
LW808_003745	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
LW808_003750	COG3202	ADP transmembrane transporter activity
LW808_003765	COG0358	DNA primase activity
LW808_003775	COG0072	phenylalanine-tRNA ligase activity
LW808_003775	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LW808_003785	COG1187	pseudouridine synthase activity
LW808_003790	COG1872	DUF167
LW808_003800	COG0427	acetyl-CoA hydrolase
LW808_003805	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
LW808_003825	COG1115	amino acid carrier protein
LW808_003835	COG0750	zinc metalloprotease
LW808_003850	COG0215	cysteine-tRNA ligase activity
LW808_003855	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LW808_003855	COG4651	solute:proton antiporter activity
LW808_003860	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
LW808_003865	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
LW808_003870	COG0355	proton-transporting ATP synthase activity, rotational mechanism
LW808_003875	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LW808_003900	COG0606	chelatase, subunit chli
LW808_003905	COG1459	type II secretion system
LW808_003910	COG1253	flavin adenine dinucleotide binding
LW808_003920	COG3850	Histidine kinase
LW808_003920	COG5002	protein histidine kinase activity
LW808_003925	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
LW808_003940	COG2001	Belongs to the MraZ family
LW808_003945	COG0275	rRNA processing
LW808_003955	COG0539	negative regulation of cytoplasmic translation
LW808_003960	COG2333	competence protein COMEC
LW808_003960	COG0658	competence protein
LW808_003965	COG0574	Belongs to the PEP-utilizing enzyme family
LW808_003965	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LW808_003970	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
LW808_003975	COG0488	(ABC) transporter
LW808_003980	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
LW808_003995	COG1074	ATP-dependent DNA helicase activity
LW808_004000	COG1385	rRNA (uridine-N3-)-methyltransferase activity
LW808_004030	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
LW808_004060	COG1640	4-alpha-glucanotransferase
LW808_004065	COG0812	UDP-N-acetylmuramate dehydrogenase activity
LW808_004070	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
LW808_004075	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LW808_004075	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LW808_004080	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity