locus-tag	class	description
EGM51_00005	ENOG4105BZU	Histidine kinase
EGM51_00010	ENOG4107STW	synthase
EGM51_00020	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
EGM51_00025	ENOG4107QRH	Arylsulfatase (Ec 3.1.6.1)
EGM51_00080	ENOG4105CHR	reductase
EGM51_00085	ENOG4107QRH	Arylsulfatase (Ec 3.1.6.1)
EGM51_00090	ENOG4105CBG	Sulfatase
EGM51_00095	ENOG4107QNK	)-transporter
EGM51_00110	ENOG4105C26	Dehydrogenase
EGM51_00150	ENOG4105QRC	ig domain protein group 2 domain protein
EGM51_00155	ENOG4105QRC	ig domain protein group 2 domain protein
EGM51_00195	ENOG4105ENE	Histidine kinase
EGM51_00205	ENOG4105QRC	ig domain protein group 2 domain protein
EGM51_00210	ENOG4105QRC	ig domain protein group 2 domain protein
EGM51_00220	ENOG4108ZGX	Histidine kinase
EGM51_00225	ENOG4105BZU	Histidine kinase
EGM51_00230	ENOG4105WH1	Two component transcriptional regulator luxr family
EGM51_00245	ENOG4105CBG	Sulfatase
EGM51_00250	ENOG4105QRC	ig domain protein group 2 domain protein
EGM51_00255	ENOG4105QRC	ig domain protein group 2 domain protein
EGM51_00270	ENOG4105CNT	hydrolase family 2
EGM51_00280	ENOG4105C26	Dehydrogenase
EGM51_00285	ENOG4105DIA	mandelate racemase muconate lactonizing
EGM51_00290	ENOG4105CPQ	Dehydrogenase
EGM51_00295	ENOG4105CHR	reductase
EGM51_00300	ENOG4105T16	Transcriptional regulator (AraC family)
EGM51_00315	ENOG4107QRH	Arylsulfatase (Ec 3.1.6.1)
EGM51_00320	ENOG4105CNT	hydrolase family 2
EGM51_00370	ENOG4105ENH	Sulfatase
EGM51_00375	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
EGM51_00380	ENOG4105CFP	Peptidase U32
EGM51_00395	ENOG4105D75	Capsular exopolysaccharide family
EGM51_00470	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
EGM51_00485	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
EGM51_00495	ENOG4107EF8	Glycosyl transferase (Group 1
EGM51_00500	ENOG4107STW	synthase
EGM51_00505	ENOG4105CG5	Glycosyl transferase (Group 1
EGM51_00510	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
EGM51_00520	ENOG4105EQK	-acetyltransferase
EGM51_00570	ENOG4105D5U	fad dependent oxidoreductase
EGM51_00575	ENOG4105EJZ	Glucose-1-phosphate cytidylyltransferase
EGM51_00585	ENOG4105FF6	Modulates transcription in response to changes in cellular NADH NAD( ) redox state (By similarity)
EGM51_00595	ENOG4105F1A	Pyruvate formate-lyase
EGM51_00640	ENOG4105EJ7	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity)
EGM51_00650	ENOG4105WQ3	Rna-binding protein
EGM51_00715	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
EGM51_00720	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
EGM51_00760	ENOG41061MV	Arylsulfatase
EGM51_00795	ENOG4105CSV	Glutaminase
EGM51_00850	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
EGM51_00930	ENOG4107SID	ATP-dependent exodnase (exonuclease v)
EGM51_00935	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
EGM51_00955	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
EGM51_01040	ENOG4105VPX	protein, conserved in bacteria
EGM51_01045	ENOG4105PGM	cation diffusion facilitator family transporter
EGM51_01210	ENOG4105VPX	protein, conserved in bacteria
EGM51_01215	ENOG4105BZU	Histidine kinase
EGM51_01220	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
EGM51_01225	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
EGM51_01255	ENOG4108IJF	Heavy metal efflux pump, CzcA
EGM51_01305	ENOG4105PUF	Ferredoxin, 2FE-2S
EGM51_01310	ENOG4105BZU	Histidine kinase
EGM51_01320	ENOG4105E4G	Type IV pilus
EGM51_01325	ENOG4107QHF	type ii secretion system protein e
EGM51_01335	ENOG4108VAU	general secretion pathway protein G
EGM51_01380	ENOG4105DF5	DNA topoisomerase IV, subunit A
EGM51_01420	ENOG4105DNX	Dna topoisomerase iv (Subunit b)
EGM51_01425	ENOG41069ER	domain protein
EGM51_01450	ENOG4105DDI	hemolysin-type calcium-binding region
EGM51_01535	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
EGM51_01540	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
EGM51_01545	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
EGM51_01550	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
EGM51_01555	ENOG4107K5T	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
EGM51_01560	ENOG4105VG0	50S ribosomal protein l34
EGM51_01565	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
EGM51_01595	ENOG4105VF7	tolerance protein
EGM51_01610	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
EGM51_01625	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
EGM51_01635	ENOG4105CIH	Imidazole acetol-phosphate transaminase
EGM51_01645	ENOG4105CJ1	ABC, transporter
EGM51_01680	ENOG41090R7	Ferric uptake
EGM51_01705	ENOG4105ENH	Sulfatase
EGM51_01715	ENOG4105CBG	Sulfatase
EGM51_01720	ENOG41061MV	Arylsulfatase
EGM51_01735	ENOG4105CNT	hydrolase family 2
EGM51_01740	ENOG4105CTB	Polyprenyl synthetase
EGM51_01775	ENOG4107VVP	(ABC) transporter
EGM51_01780	ENOG4105FDK	ABC transporter
EGM51_01785	ENOG4105DSE	periplasmic solute binding protein
EGM51_01790	ENOG4105VZ9	UPF0235 protein
EGM51_01800	ENOG4105FB9	CRISPR-associated protein
EGM51_01825	ENOG4105DYN	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)
EGM51_01830	ENOG4105KCF	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease (By similarity)
EGM51_01835	ENOG4105CPF	Cell wall formation (By similarity)
EGM51_01840	ENOG410827V	cell division protein FtsQ
EGM51_01845	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
EGM51_01855	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
EGM51_01860	ENOG4105C5X	domain protein
EGM51_01890	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
EGM51_01895	ENOG4107SC0	ferredoxin--NADP reductase
EGM51_01910	ENOG4108RWN	rrna methyltransferase
EGM51_01915	ENOG4105DFU	Cell wall formation (By similarity)
EGM51_01925	ENOG4107QHI	-hydrogenase
EGM51_01930	ENOG4107QIZ	NADH dehydrogenase
EGM51_01940	ENOG4105BZU	Histidine kinase
EGM51_01945	ENOG410902H	NADH dehydrogenase (Ubiquinone), 24 kDa subunit
EGM51_01950	ENOG4105FF6	Modulates transcription in response to changes in cellular NADH NAD( ) redox state (By similarity)
EGM51_01955	ENOG4105EE0	oxidoreductase
EGM51_01960	ENOG4105DG6	mannose-6-phosphate isomerase
EGM51_01965	ENOG4105CNT	hydrolase family 2
EGM51_01970	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
EGM51_01975	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
EGM51_01980	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
EGM51_01985	ENOG4105M7K	Involved in the transcription termination process (By similarity)
EGM51_01990	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
EGM51_02000	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
EGM51_02005	ENOG4108R6K	riboflavin synthase, subunit alpha
EGM51_02010	ENOG4108R6K	riboflavin synthase, subunit alpha
EGM51_02015	ENOG4105PXI	polysaccharide deacetylase
EGM51_02020	ENOG4105E1F	short-chain dehydrogenase reductase
EGM51_02035	ENOG4108YXI	Secondary thiamine-phosphate synthase enzyme
EGM51_02040	ENOG4108JU6	CBS domain protein
EGM51_02055	ENOG4108KNB	n-acetylmuramoyl-l-alanine amidase
EGM51_02060	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
EGM51_02070	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
EGM51_02090	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
EGM51_02100	ENOG4105CJN	penicillin-binding protein
EGM51_02105	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
EGM51_02110	ENOG4107EES	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity)
EGM51_02115	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
EGM51_02120	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
EGM51_02125	ENOG41068KG	domain protein
EGM51_02130	ENOG4105CNI	cell division protein FtsW
EGM51_02135	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
EGM51_02140	ENOG4108YBP	pseudouridine synthase
EGM51_02145	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
EGM51_02150	ENOG4108DBC	nitroreductase
EGM51_02195	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
EGM51_02205	ENOG4105C3D	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
EGM51_02220	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
EGM51_02225	ENOG4105D3Q	Sugar transferase
EGM51_02230	ENOG41084GC	stage II sporulation protein
EGM51_02235	ENOG4107V9E	glucose-1-phosphate thymidylyltransferase
EGM51_02240	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
EGM51_02245	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
EGM51_02255	ENOG4105BZU	Histidine kinase
EGM51_02270	ENOG4105DZP	Membrane-associated zinc metalloprotease
EGM51_02275	ENOG4105KNE	Phosphatidate cytidylyltransferase
EGM51_02285	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
EGM51_02295	ENOG4105DTN	riboflavin biosynthesis protein ribF
EGM51_02300	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
EGM51_02305	ENOG41084NN	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
EGM51_02325	ENOG4107QSA	Oxaloacetate decarboxylase
EGM51_02330	ENOG4105D9Q	decarboxylase (Beta subunit)
EGM51_02340	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
EGM51_02345	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EGM51_02380	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
EGM51_02385	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
EGM51_02390	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
EGM51_02400	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
EGM51_02410	ENOG4108ZAI	phosphatidylglycerophosphatase a
EGM51_02420	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
EGM51_02425	ENOG4105C4X	radical SAM domain protein
EGM51_02430	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
EGM51_02435	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
EGM51_02440	ENOG410845M	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes (By similarity)
EGM51_02465	ENOG4105D6E	homoserine dehydrogenase
EGM51_02470	ENOG4105CFH	Aspartokinase
EGM51_02475	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
EGM51_02480	ENOG4105E1F	short-chain dehydrogenase reductase
EGM51_02520	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
EGM51_02525	ENOG4105CRK	lysyL-tRNA synthetase
EGM51_02535	ENOG4108JA2	transcriptioN-repair coupling factor
EGM51_02540	ENOG4105CXT	aspartate transcarbamylase
EGM51_02545	ENOG4105DBV	ornithine carbamoyltransferase
EGM51_02550	ENOG4105D16	lipopolysaccharide heptosyltransferase i
EGM51_02560	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
EGM51_02570	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
EGM51_02575	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
EGM51_02580	ENOG4105CSD	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
EGM51_02595	ENOG41061MV	Arylsulfatase
EGM51_02605	ENOG4108WBT	adenosyltransferase
EGM51_02615	ENOG4105ECK	Fatty Acid Desaturase
EGM51_02625	ENOG4105K5M	30s ribosomal protein S16
EGM51_02630	ENOG4105VB6	UPF0109 protein
EGM51_02640	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
EGM51_02645	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
EGM51_02650	ENOG41080V7	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
EGM51_02660	ENOG4105C9A	Phoh family
EGM51_02670	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
EGM51_02695	ENOG4105T16	Transcriptional regulator (AraC family)
EGM51_02705	ENOG4108UHU	Aldolase
EGM51_02710	ENOG4108YXG	UPF0502 protein
EGM51_02715	ENOG4105CBG	Sulfatase
EGM51_02725	ENOG4105CJW	magnesium transporter
EGM51_02730	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
EGM51_02750	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
EGM51_02780	ENOG4105E09	nadh pyrophosphatase
EGM51_02840	ENOG4106855	Competence protein
EGM51_02845	ENOG4105C12	Phosphoribosylglycinamide synthetase
EGM51_02855	ENOG4105VRS	hydrolase family 18
EGM51_02910	ENOG4105BZU	Histidine kinase
EGM51_02915	ENOG4105C9U	ATP-dependent DNA helicase RecQ
EGM51_02960	ENOG4105CVS	RNA methyltransferase TrmH family, group 1
EGM51_02970	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
EGM51_02975	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
EGM51_02980	ENOG4107QSN	dihydrolipoamide acetyltransferase
EGM51_02990	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
EGM51_02995	ENOG4105N5T	Radical SAM Protein
EGM51_03000	ENOG4105CD3	dihydroorotase
EGM51_03005	ENOG4105DKF	Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) (By similarity)
EGM51_03025	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
EGM51_03040	ENOG4108Q52	Methyltransferase cognate corrinoid protein
EGM51_03045	ENOG4105CKU	formyltetrahydrofolate synthetase
EGM51_03050	ENOG4105TMB	Formate nitrite transporter
EGM51_03060	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
EGM51_03065	ENOG410874W	AraC family transcriptional regulator
EGM51_03075	ENOG4105D16	lipopolysaccharide heptosyltransferase i
EGM51_03085	ENOG4105CUY	Mechanosensitive ion channel
EGM51_03095	ENOG4105DHI	Methyltransferase
EGM51_03100	ENOG4105BZK	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity)
EGM51_03105	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
EGM51_03120	ENOG4105CMR	udp-glucose 4-epimerase
EGM51_03125	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
EGM51_03130	ENOG4108BRW	Activates expression of the rhaSR operon in response to L-rhamnose (By similarity)
EGM51_03155	ENOG4107S6Z	Na H antiporter
EGM51_03200	ENOG41061MV	Arylsulfatase
EGM51_03225	ENOG41084I7	Alpha-galactosidase. Removes both branched alpha-1,3- linked galactose residues of blood group B antigens and linear alpha-1,3-linked galactose structures
EGM51_03230	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
EGM51_03235	ENOG41061MV	Arylsulfatase
EGM51_03245	ENOG4105T16	Transcriptional regulator (AraC family)
EGM51_03250	ENOG4107QZW	Altronate oxidoreductase
EGM51_03260	ENOG4105CNT	hydrolase family 2
EGM51_03275	ENOG41061MV	Arylsulfatase
EGM51_03290	ENOG4105CBG	Sulfatase
EGM51_03295	ENOG4105CBG	Sulfatase
EGM51_03330	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
EGM51_03335	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
EGM51_03345	ENOG4105CUX	Signal transduction histidine kinase
EGM51_03350	ENOG4105C8P	)-transporter
EGM51_03360	ENOG41082SS	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions (By similarity)
EGM51_03365	ENOG4105CUT	histidyl-tRNA synthetase
EGM51_03370	ENOG4105C9M	aspartyl-trna synthetase
EGM51_03375	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
EGM51_03395	ENOG4108IUZ	ABC transporter
EGM51_03410	ENOG4105KZ7	phosphocarrier protein hpr
EGM51_03415	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
EGM51_03435	ENOG4108YZS	Had-superfamily hydrolase, subfamily ia, variant 1
EGM51_03450	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
EGM51_03475	ENOG4108QJ2	2,3-dihydroxy-2,3-dihydrophenylpropionate dehydrogenase
EGM51_03485	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
EGM51_03490	ENOG4105K4H	Nlp p60 protein
EGM51_03505	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
EGM51_03515	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
EGM51_03525	ENOG4105C1J	atp-dependent rna helicase
EGM51_03535	ENOG41067VY	50S ribosomal protein L32
EGM51_03540	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
EGM51_03550	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
EGM51_03555	ENOG4105CHR	reductase
EGM51_03560	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
EGM51_03565	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
EGM51_03570	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
EGM51_03600	ENOG4109015	Biopolymer transport protein exbD tolR
EGM51_03605	ENOG4109015	Biopolymer transport protein exbD tolR
EGM51_03635	ENOG4105D1S	lipid A biosynthesis
EGM51_03645	ENOG4105DGN	Electron transport complex
EGM51_03650	ENOG4108R3D	Electron transport complex
EGM51_03655	ENOG4107QTR	Required for nitrogen fixation. May be part of a membrane complex functioning as an intermediate in the electron transport to nitrogenase (By similarity)
EGM51_03660	ENOG4105D6A	Electron transport complex
EGM51_03670	ENOG4108UQQ	Electron transport complex
EGM51_03675	ENOG4105DZB	Electron transport complex
EGM51_03755	ENOG4107U85	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
EGM51_03760	ENOG4105D9P	serine threonine protein kinase
EGM51_03765	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
EGM51_03770	ENOG4105D64	Mechanosensitive ion channel
EGM51_03775	ENOG4105CN1	protease
EGM51_03780	ENOG4105C89	phosphohexose isomerase
EGM51_03800	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EGM51_03810	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
EGM51_03880	ENOG4105CHM	Aminotransferase
EGM51_03885	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
EGM51_03900	ENOG4108A65	Transcriptional regulator
EGM51_03905	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
EGM51_03910	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
EGM51_03915	ENOG4105FEU	K -dependent Na -Ca exchanger
EGM51_03920	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
EGM51_03930	ENOG4105CK7	Sodium proline symporter
EGM51_03935	ENOG4105CN9	Peptidase m42 family protein
EGM51_03950	ENOG4108JMC	lipopolysaccharide core biosynthesis protein
EGM51_03955	ENOG4107RJ7	Glycosyl transferase (Group 1
EGM51_03960	ENOG4107543	(lipo)polysaccharide
EGM51_03980	ENOG4105BZ1	(ABC) transporter
EGM51_03995	ENOG4105C6E	dna polymerase iii
EGM51_04000	ENOG410816I	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
EGM51_04005	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
EGM51_04095	ENOG4105D82	Glutamate dehydrogenase
EGM51_04100	ENOG4105D82	Glutamate dehydrogenase
EGM51_04105	ENOG4107R1M	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) (By similarity)
EGM51_04135	ENOG4106KS4	Sulfatase
EGM51_04145	ENOG4105CBG	Sulfatase
EGM51_04160	ENOG4105ENH	Sulfatase
EGM51_04185	ENOG4105CNT	hydrolase family 2
EGM51_04195	ENOG4105E2V	Glycosyltransferase 36
EGM51_04230	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
EGM51_04235	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
EGM51_04240	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
EGM51_04250	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
EGM51_04255	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
EGM51_04260	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
EGM51_04265	ENOG4105CJR	Integral membrane protein (MviN
EGM51_04305	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
EGM51_04320	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
EGM51_04325	ENOG4105XMA	
EGM51_04330	ENOG4105C0M	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle (By similarity)
EGM51_04340	ENOG41084I7	Alpha-galactosidase. Removes both branched alpha-1,3- linked galactose residues of blood group B antigens and linear alpha-1,3-linked galactose structures
EGM51_04350	ENOG4105CK7	Sodium proline symporter
EGM51_04360	ENOG4107QRH	Arylsulfatase (Ec 3.1.6.1)
EGM51_04375	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
EGM51_04380	ENOG4105D78	K07001 NTE family protein
EGM51_04390	ENOG4105DE4	1-phosphofructokinase
EGM51_04405	ENOG4105CEY	Amp-dependent synthetase and ligase
EGM51_04410	ENOG4108JUA	Transcriptional regulator
EGM51_04420	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
EGM51_04425	ENOG4105CE9	30S ribosomal protein S2
EGM51_04430	ENOG4105C7Z	Conserved Protein
EGM51_04450	ENOG4108VAU	general secretion pathway protein G
EGM51_04455	ENOG4105D7Q	type ii secretion system
EGM51_04485	ENOG4105C8V	SAICAR synthetase
EGM51_04570	ENOG41061MV	Arylsulfatase
EGM51_04585	ENOG41061MV	Arylsulfatase
EGM51_04590	ENOG4108XG2	Histidine kinase
EGM51_04595	ENOG4105WH1	Two component transcriptional regulator luxr family
EGM51_04635	ENOG4107RJ5	oxidoreductase
EGM51_04670	ENOG4105DX1	Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation (By similarity)
EGM51_04680	ENOG41061MV	Arylsulfatase
EGM51_04685	ENOG4108K2B	transcriptional regulator
EGM51_04710	ENOG4105ETE	Transcriptional regulator (LacI family
EGM51_04740	ENOG4105BZU	Histidine kinase
EGM51_04745	ENOG4105WH1	Two component transcriptional regulator luxr family
EGM51_04760	ENOG41061MV	Arylsulfatase
EGM51_04765	ENOG4107QRH	Arylsulfatase (Ec 3.1.6.1)
EGM51_04770	ENOG41061MV	Arylsulfatase
EGM51_04775	ENOG4108KBQ	ec 3.2.1.81
EGM51_04810	ENOG4105CBG	Sulfatase
EGM51_04820	ENOG4108KBQ	ec 3.2.1.81
EGM51_04840	ENOG4105CT4	transporter
EGM51_04855	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
EGM51_04865	ENOG4105ENE	Histidine kinase
EGM51_04870	ENOG4105WH1	Two component transcriptional regulator luxr family
EGM51_04875	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
EGM51_04890	ENOG4108KBQ	ec 3.2.1.81
EGM51_04910	ENOG4105CBG	Sulfatase
EGM51_04920	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
EGM51_04930	ENOG4105CBG	Sulfatase
EGM51_04945	ENOG4105CBG	Sulfatase
EGM51_04975	ENOG4105CNT	hydrolase family 2
EGM51_05010	ENOG4105ECQ	AraC Family Transcriptional Regulator
EGM51_05015	ENOG4105F66	Binding-protein-dependent transport systems inner membrane component
EGM51_05025	ENOG4105DB9	Binding-protein-dependent transport systems inner membrane component
EGM51_05035	ENOG4105ID8	Transcriptional regulator, ARAC family
EGM51_05040	ENOG4105CBG	Sulfatase
EGM51_05060	ENOG4105C4C	beta-galactosidase
EGM51_05065	ENOG4107QZF	nitrite reductase NADPH large subunit
EGM51_05070	ENOG4105CSA	Coproporphyrinogen iii oxidase
EGM51_05075	ENOG41087N2	50S ribosomal protein l28
EGM51_05080	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
EGM51_05100	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
EGM51_05105	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
EGM51_05110	ENOG4105CM2	brancheD-chain amino acid aminotransferase
EGM51_05120	ENOG41066A3	ATP guanido phosphotransferase
EGM51_05125	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
EGM51_05140	ENOG4105C75	arginyL-tRNA synthetase
EGM51_05150	ENOG4105C37	(CBS) domain
EGM51_05175	ENOG4105CJ2	(LipO)protein
EGM51_05185	ENOG4107QQN	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
EGM51_05190	ENOG4105C7H	Helicase, RecD TraA family
EGM51_05215	ENOG41063TF	transcriptional regulator (AraC
EGM51_05240	ENOG4107RF2	cellulose-binding family II protein
EGM51_05250	ENOG4105CBG	Sulfatase
EGM51_05265	ENOG4105CK5	oxidoreductase
EGM51_05275	ENOG4105ENH	Sulfatase
EGM51_05295	ENOG4105WH1	Two component transcriptional regulator luxr family
EGM51_05300	ENOG41061MV	Arylsulfatase
EGM51_05305	ENOG4105CBG	Sulfatase
EGM51_05325	ENOG4107QRH	Arylsulfatase (Ec 3.1.6.1)
EGM51_05340	ENOG4105WH1	Two component transcriptional regulator luxr family
EGM51_05345	ENOG4108ZGX	Histidine kinase
EGM51_05360	ENOG4105WH1	Two component transcriptional regulator luxr family
EGM51_05365	ENOG4105ENE	Histidine kinase
EGM51_05385	ENOG4107QRH	Arylsulfatase (Ec 3.1.6.1)
EGM51_05410	ENOG4105QNJ	serralysin (EC 3.4.24.40)
EGM51_05425	ENOG4107RF2	cellulose-binding family II protein
EGM51_05430	ENOG41061MV	Arylsulfatase
EGM51_05450	ENOG4105CBG	Sulfatase
EGM51_05455	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
EGM51_05490	ENOG4105ENH	Sulfatase
EGM51_05550	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
EGM51_05555	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
EGM51_05560	ENOG4105EQD	regulatoR
EGM51_05570	ENOG4105CNT	hydrolase family 2
EGM51_05600	ENOG4108YZ4	nudix hydrolase
EGM51_05605	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
EGM51_05620	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
EGM51_05635	ENOG4105FE9	pseudouridine synthase
EGM51_05650	ENOG4108Z6K	Catalyzes the circularization of gamma-N-acetyl- alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6- tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant (By similarity)
EGM51_05655	ENOG4108JPW	Aminotransferase
EGM51_05665	ENOG4108VHT	MarR family transcriptional regulator
EGM51_05670	ENOG4105D1Q	UPF0246 protein
EGM51_05680	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
EGM51_05690	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
EGM51_05700	ENOG4108IAB	Phoh family
EGM51_05710	ENOG4108DGI	Phosphoribosylformylglycinamidine synthase I
EGM51_05715	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
EGM51_05720	ENOG4107QW3	Sucrose phosphorylase
EGM51_05725	ENOG4105IRK	Glycosyl transferase (Group 1
EGM51_05735	ENOG4105C3Q	Glycosyl transferase, family 2
EGM51_05745	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
EGM51_05755	ENOG4107S6X	Glycosyl transferase, family 2
EGM51_05800	ENOG4105E0M	Sulfatase
EGM51_05805	ENOG4105CQ7	ATP-dependent helicase
EGM51_05810	ENOG4105MN5	HAD-superfamily hydrolase subfamily IA variant 3
EGM51_05815	ENOG4105C2X	Arabinose 5-phosphate isomerase
EGM51_05825	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
EGM51_05840	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
EGM51_05850	ENOG4105FDK	ABC transporter
EGM51_05860	ENOG4105C9U	ATP-dependent DNA helicase RecQ
EGM51_05875	ENOG4105CAT	Cytidine monophosphate kinase
EGM51_05880	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
EGM51_05890	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
EGM51_05895	ENOG4105CBG	Sulfatase
EGM51_05905	ENOG4105DX0	Hemolysin A
EGM51_05920	ENOG4105D9H	Catalyzes the attachment of glycine to tRNA(Gly) (By similarity)
EGM51_05935	ENOG4107RT4	flavin reductase domain protein
EGM51_05955	ENOG4105DHJ	ABC, transporter
EGM51_05980	ENOG4105VG1	fes assembly suf system protein
EGM51_05990	ENOG4105C9B	Cysteine desulfurase
EGM51_06000	ENOG4105C3K	feS assembly ATPase SufC
EGM51_06015	ENOG4105DXN	mazG family
EGM51_06025	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
EGM51_06030	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
EGM51_06035	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
EGM51_06040	ENOG4105XA0	heptosyltransferase ii
EGM51_06045	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
EGM51_06050	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
EGM51_06055	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
EGM51_06065	ENOG4105DTC	1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (air) carboxylase
EGM51_06070	ENOG4105FUQ	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
EGM51_06075	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
EGM51_06080	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
EGM51_06090	ENOG4105ENH	Sulfatase
EGM51_06095	ENOG4105CBG	Sulfatase
EGM51_06100	ENOG4108MCI	Transcriptional regulator, ARAC family
EGM51_06115	ENOG4105CXK	mandelate racemase muconate lactonizing
EGM51_06120	ENOG4105C26	Dehydrogenase
EGM51_06125	ENOG4108UHU	Aldolase
EGM51_06155	ENOG4108MGF	sugar kinase
EGM51_06160	ENOG4105D2N	Aldolase
EGM51_06165	ENOG4105CNT	hydrolase family 2
EGM51_06170	ENOG41061MV	Arylsulfatase
EGM51_06175	ENOG41061MV	Arylsulfatase
EGM51_06205	ENOG4105EZV	Transcriptional regulator
EGM51_06210	ENOG4105CNT	hydrolase family 2
EGM51_06230	ENOG4105CHZ	Catalyzes the dehydration of D-mannonate (By similarity)
EGM51_06255	ENOG4107QRH	Arylsulfatase (Ec 3.1.6.1)
EGM51_06265	ENOG4108KBQ	ec 3.2.1.81
EGM51_06270	ENOG4108KBQ	ec 3.2.1.81
EGM51_06280	ENOG4105QRC	ig domain protein group 2 domain protein
EGM51_06305	ENOG4105CNT	hydrolase family 2
EGM51_06315	ENOG4105ETE	Transcriptional regulator (LacI family
EGM51_06320	ENOG4105CGK	Exodeoxyribonuclease III
EGM51_06325	ENOG4105CNG	UPF0061 protein
EGM51_06330	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
EGM51_06340	ENOG4105DWQ	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
EGM51_06345	ENOG4108J5C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
EGM51_06350	ENOG4106I92	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
EGM51_06355	ENOG4105F5D	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
EGM51_06360	ENOG4108IUB	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
EGM51_06370	ENOG4105CSR	polyphosphate kinase 2
EGM51_06375	ENOG4105CHH	sulfate transporter
EGM51_06380	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
EGM51_06385	ENOG4105IIU	Aminopeptidase
EGM51_06400	ENOG4107RVI	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit (By similarity)
EGM51_06405	ENOG4107RQX	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
EGM51_06410	ENOG4108WBK	V-type ATP synthase subunit D
EGM51_06430	ENOG4105EGD	dinuclear metal center protein, YbgI family
EGM51_06435	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
EGM51_06440	ENOG4106KS4	Sulfatase
EGM51_06445	ENOG4105D4A	Cell wall formation (By similarity)
EGM51_06465	ENOG4105CIH	Imidazole acetol-phosphate transaminase
EGM51_06490	ENOG4105DZS	Phenylacetate-CoA ligase
EGM51_06505	ENOG4105DZS	Phenylacetate-CoA ligase
EGM51_06510	ENOG4105C3J	Cysteine desulfurase
EGM51_06515	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
EGM51_06520	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
EGM51_06525	ENOG4105CTQ	phosphohexokinase
EGM51_06530	ENOG4105CGH	5'-nucleotidase
EGM51_06535	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
EGM51_06540	ENOG4105C9X	ppx gppa phosphatase
EGM51_06545	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
EGM51_06560	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
EGM51_06565	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
EGM51_06570	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
EGM51_06590	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
EGM51_06600	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
EGM51_06610	ENOG41082RQ	UPF0102 protein
EGM51_06615	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
EGM51_06620	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
EGM51_06640	ENOG4107QJE	Chromosome Partitioning Protein
EGM51_06650	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
EGM51_06660	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
EGM51_06675	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
EGM51_06685	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
EGM51_06690	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
EGM51_06710	ENOG4108Z6B	deaminase
EGM51_06715	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
EGM51_06725	ENOG4105BZ1	(ABC) transporter
EGM51_06730	ENOG4105BZ1	(ABC) transporter
EGM51_06735	ENOG4105CHR	reductase
EGM51_06740	ENOG4105IQ5	FAD linked oxidase domain protein
EGM51_06750	ENOG4107QSV	RmuC domain protein
EGM51_06755	ENOG4107QW8	radical SAM domain protein
EGM51_06760	ENOG4105D41	biosynthesis protein thiH
EGM51_06765	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
EGM51_06775	ENOG4108IJ0	Aspartate ammonia-lyase
EGM51_06810	ENOG4105E0M	Sulfatase
EGM51_06830	ENOG4105KPK	Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation (By similarity)
EGM51_06835	ENOG4105ETE	Transcriptional regulator (LacI family
EGM51_06840	ENOG4105ETE	Transcriptional regulator (LacI family
EGM51_06855	ENOG4105NAE	bifunctional deaminase-reductase domain protein
EGM51_06885	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
EGM51_06900	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
EGM51_06960	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
EGM51_06965	ENOG4105C4K	Nad synthetase
EGM51_06980	ENOG4105DDQ	anthranilate synthase
EGM51_06990	ENOG4105CRQ	synthase (Component I)
EGM51_06995	ENOG4105QRC	ig domain protein group 2 domain protein
EGM51_07005	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
EGM51_07010	ENOG4108R88	cytochrome C
EGM51_07015	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
EGM51_07025	ENOG4105C8M	UPF0272 protein
EGM51_07030	ENOG4105W5Q	DNA repair protein (RadC
EGM51_07035	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
EGM51_07040	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
EGM51_07045	ENOG4105C8J	)-transporter
EGM51_07050	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
EGM51_07055	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
EGM51_07060	ENOG4105CZX	twitching motility protein
EGM51_07070	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
EGM51_07075	ENOG4107RUK	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins (By similarity)
EGM51_07085	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
EGM51_07090	ENOG4106A3M	Cytochrome p-450
EGM51_07095	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
EGM51_07105	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
EGM51_07135	ENOG4105F99	Hydroxymethylglutaryl-CoA synthase
EGM51_07145	ENOG4108ZJT	translation initiation factor, Sui1
EGM51_07150	ENOG4105QNR	S1 RNA binding domain protein
EGM51_07155	ENOG4105C1J	atp-dependent rna helicase
EGM51_07180	ENOG4108UK2	deaminase
EGM51_07190	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
EGM51_07195	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
EGM51_07200	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
EGM51_07210	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
EGM51_07215	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
EGM51_07220	ENOG4109015	Biopolymer transport protein exbD tolR
EGM51_07225	ENOG4109015	Biopolymer transport protein exbD tolR
EGM51_07250	ENOG4105C34	Pseudouridine synthase
EGM51_07275	ENOG4105W3S	hemerythrin-like, metal-binding protein
EGM51_07280	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
EGM51_07315	ENOG4105CUZ	uba thif-type nad fad binding protein
EGM51_07350	ENOG4109015	Biopolymer transport protein exbD tolR
EGM51_07405	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
EGM51_07410	ENOG4105BZU	Histidine kinase
EGM51_07435	ENOG4105CVA	phosphate
EGM51_07440	ENOG4105C8U	phosphate abc transporter
EGM51_07445	ENOG4105E2Z	phosphate ABC transporter (Permease
EGM51_07450	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
EGM51_07455	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
EGM51_07485	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
EGM51_07510	ENOG4107XPQ	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
EGM51_07515	ENOG4105EAU	Plays a role in nitrite reduction (By similarity)
EGM51_07520	ENOG4108W6G	cytochrome C
EGM51_07525	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
EGM51_07530	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
EGM51_07535	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
EGM51_07545	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
EGM51_07555	ENOG4105DEF	Extracellular solute-binding protein, family 5
EGM51_07565	ENOG4105CP7	Triose-phosphate isomerase
EGM51_07580	ENOG4105C2M	dna polymerase I
EGM51_07610	ENOG4105BZU	Histidine kinase
EGM51_07620	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
EGM51_07625	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
EGM51_07630	ENOG4105VB5	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
EGM51_07655	ENOG4105DFU	Cell wall formation (By similarity)
EGM51_07670	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
EGM51_07680	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
EGM51_07685	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
EGM51_07710	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
EGM51_07730	ENOG41090A1	ferritin
EGM51_07735	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
EGM51_07755	ENOG4107RGW	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EGM51_07760	ENOG4107QK8	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EGM51_07790	ENOG4105D22	carbon starvation protein
EGM51_07795	ENOG4105EUJ	GTP cyclohydrolase i
EGM51_07810	ENOG4105CBG	Sulfatase
EGM51_07815	ENOG4105E68	Sulfatase
EGM51_07820	ENOG4105CBG	Sulfatase
EGM51_07830	ENOG4105CBG	Sulfatase
EGM51_07835	ENOG4105CPC	Aldo Keto reductase
EGM51_07840	ENOG4105CNT	hydrolase family 2
EGM51_07855	ENOG4105C6Q	that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of
EGM51_07860	ENOG4107WTH	Galactitol-1-phosphate dehydrogenase
EGM51_07865	ENOG4107QVN	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
EGM51_07870	ENOG4105CVJ	phosphoglycerate mutase
EGM51_07880	ENOG4105EDR	glucose galactose transporter
EGM51_07905	ENOG4105C01	Dihydroxy-acid dehydratase
EGM51_07910	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
EGM51_07915	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
EGM51_07920	ENOG4105D3Q	Sugar transferase
EGM51_07955	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
EGM51_07965	ENOG4107XB0	Lipopolysaccharide 1,2-N-acetylglucosaminetransferase
EGM51_07980	ENOG4105JNK	Glycosyl transferase (Group 1
EGM51_07995	ENOG4105DKP	glycosyl transferase, family 9
EGM51_08015	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
EGM51_08030	ENOG4105C30	Nad-dependent epimerase dehydratase
EGM51_08040	ENOG4105C0K	Gdp-mannose 4,6-dehydratase
EGM51_08045	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
EGM51_08065	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
EGM51_08075	ENOG4105C11	sulfate adenylyltransferase), subunit 2
EGM51_08085	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
EGM51_08090	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
EGM51_08105	ENOG4105E1Q	flagellar hook-associated protein
EGM51_08120	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
EGM51_08125	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
EGM51_08130	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
EGM51_08140	ENOG4105CGA	flagellar basal-body rod protein FlgG
EGM51_08145	ENOG4108JQA	flagellar
EGM51_08150	ENOG4105DD5	Flagellar motor switch protein
EGM51_08155	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
EGM51_08170	ENOG4105ER2	Ompa motb domain protein
EGM51_08175	ENOG4105E14	MotA TolQ exbB proton channel
EGM51_08185	ENOG4108JQA	flagellar
EGM51_08190	ENOG410822I	Flagellar hook capping protein
EGM51_08220	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
EGM51_08225	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
EGM51_08235	ENOG4108ZC9	flagellar basal-body rod protein flgc
EGM51_08240	ENOG4105Q75	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
EGM51_08245	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
EGM51_08250	ENOG4108ZXC	Two component transcriptional regulator, luxr family
EGM51_08255	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
EGM51_08260	ENOG4105BZU	Histidine kinase
EGM51_08265	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
EGM51_08280	ENOG4105D7B	Flagellar biosynthesis protein flha
EGM51_08285	ENOG4105D00	flagellar biosynthetic protein flhB
EGM51_08290	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
EGM51_08300	ENOG4105CN7	Flagellar biosynthetic protein FliP
EGM51_08315	ENOG4105MQ3	flagellar protein FliS
EGM51_08320	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
EGM51_08330	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
EGM51_08345	ENOG4105BZU	Histidine kinase
EGM51_08355	ENOG4105I03	Flagellin
EGM51_08360	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
EGM51_08365	ENOG4105W5T	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum (By similarity)
EGM51_08370	ENOG4105CAQ	asparagine synthetase
EGM51_08375	ENOG4107TPX	flagellar hook-associated
EGM51_08385	ENOG4105I03	Flagellin
EGM51_08390	ENOG4105I03	Flagellin
EGM51_08395	ENOG4105I03	Flagellin
EGM51_08415	ENOG4105BZU	Histidine kinase
EGM51_08425	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
EGM51_08430	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
EGM51_08445	ENOG4107MHI	Transcriptional regulator, MarR family
EGM51_08450	ENOG4105EJU	HAD-superfamily hydrolase subfamily IA variant 3
EGM51_08460	ENOG4105FE9	pseudouridine synthase
EGM51_08480	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
EGM51_08485	ENOG4105C1A	potassium transporter peripheral membrane
EGM51_08500	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
EGM51_08505	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
EGM51_08520	ENOG4105C7K	acetolactate synthase
EGM51_08535	ENOG4105C85	amino acid
EGM51_08540	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
EGM51_08550	ENOG4105CGM	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
EGM51_08555	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
EGM51_08560	ENOG4105DSF	transport protein
EGM51_08605	ENOG4105D3R	alkyl hydroperoxide reductase
EGM51_08610	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
EGM51_08620	ENOG4105DZ1	carboxypeptidase
EGM51_08630	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
EGM51_08635	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
EGM51_08640	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
EGM51_08665	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
EGM51_08675	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
EGM51_08695	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
EGM51_08705	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
EGM51_08720	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
EGM51_08725	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
EGM51_08760	ENOG41089BK	Glutamine amido-transferase
EGM51_08765	ENOG4105D9R	oxidoreductase
EGM51_08770	ENOG4105D9R	oxidoreductase
EGM51_08775	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
EGM51_08805	ENOG4108JJ9	ABC, transporter
EGM51_08820	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
EGM51_08825	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
EGM51_08845	ENOG4105CJW	magnesium transporter
EGM51_08850	ENOG4108SAY	Involved in DNA repair and RecF pathway recombination (By similarity)
EGM51_08860	ENOG4105K64	Glycosyl transferase, family 2
EGM51_08870	ENOG4105F0R	Cytidylyltransferase
EGM51_08915	ENOG4107R8N	Glycosyl transferase, family 2
EGM51_08940	ENOG4105CG5	Glycosyl transferase (Group 1
EGM51_08945	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
EGM51_08950	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
EGM51_08955	ENOG4105CBG	Sulfatase
EGM51_08965	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
EGM51_08970	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
EGM51_08975	ENOG4107TEJ	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
EGM51_08980	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EGM51_08985	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
EGM51_09000	ENOG4105BZA	Phosphoglycerate kinase
EGM51_09025	ENOG41079HR	Phosphate-Selective Porin O and P
EGM51_09030	ENOG41080WF	Electron transport complex, RnfABCDGE type, G subunit
EGM51_09050	ENOG4105C3M	thioredoxin reductase
EGM51_09055	ENOG4107QN2	dihydrolipoyl dehydrogenase
EGM51_09070	ENOG4105C22	threonyL-tRNA synthetase
EGM51_09075	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
EGM51_09085	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
EGM51_09100	ENOG4108RAV	Conserved protein
EGM51_09105	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
EGM51_09110	ENOG4107QRG	dna polymerase iii
EGM51_09115	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
EGM51_09120	ENOG4105C8N	cysteinyl-tRNA synthetase
EGM51_09125	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
EGM51_09130	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
EGM51_09140	ENOG4107YJ4	chain length determinant protein
EGM51_09145	ENOG4105HTX	biosynthesis protein
EGM51_09170	ENOG4107FSS	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
EGM51_09175	ENOG4109015	Biopolymer transport protein exbD tolR
EGM51_09180	ENOG4109015	Biopolymer transport protein exbD tolR
EGM51_09185	ENOG4108PAU	MotA TolQ exbB proton channel
EGM51_09205	ENOG41082DI	50s ribosomal protein l31
EGM51_09210	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
EGM51_09225	ENOG4108IYU	L-aspartate oxidase
EGM51_09265	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
EGM51_09270	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
EGM51_09310	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
EGM51_09325	ENOG4105DMW	Dehydrogenase reductase
EGM51_09335	ENOG4105WD1	Membrane
EGM51_09345	ENOG4105CRQ	synthase (Component I)
EGM51_09355	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
EGM51_09395	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
EGM51_09400	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
EGM51_09405	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
EGM51_09415	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EGM51_09470	ENOG4107QMH	DNA methylase
EGM51_09475	ENOG4105C0D	helicase
EGM51_09480	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
EGM51_09485	ENOG4105C4U	4-methyl-5-beta-hydroxyethylthiazole kinase
EGM51_09505	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
EGM51_09515	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
EGM51_09520	ENOG4108I6A	alcohol dehydrogenase
EGM51_09530	ENOG41084M5	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
EGM51_09535	ENOG4105CHR	reductase
EGM51_09545	ENOG4108IND	Tetr family transcriptional regulator
EGM51_09600	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
EGM51_09615	ENOG4105EV6	Pfam:DUF178
EGM51_09620	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
EGM51_09625	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
EGM51_09630	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
EGM51_09635	ENOG4105E63	Pfam:DUF178
EGM51_09640	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
EGM51_09645	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
EGM51_09650	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
EGM51_09670	ENOG4105IJJ	transcriptional regulator, crp fnr family
EGM51_09680	ENOG4105CKI	cobalamin synthesis protein
EGM51_09685	ENOG4105C5H	ABC transporter
EGM51_09710	ENOG4105D2H	Uronic isomerase
EGM51_09720	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
EGM51_09725	ENOG4105EDK	PfkB domain protein
EGM51_09730	ENOG4105CHZ	Catalyzes the dehydration of D-mannonate (By similarity)
EGM51_09735	ENOG4108MGY	Histidine kinase
EGM51_09770	ENOG4108RR8	protoporphyrinogen oxidase
EGM51_09890	ENOG4108KQ5	Integrase catalytic subunit
EGM51_09995	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
EGM51_10000	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
EGM51_10015	ENOG4105DHJ	ABC, transporter
EGM51_10040	ENOG4105D7W	serine acetyltransferase
EGM51_10045	ENOG4105VJV	50s ribosomal protein L35
EGM51_10050	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
EGM51_10055	ENOG4108I0Q	anthranilate phosphoribosyltransferase
EGM51_10060	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EGM51_10065	ENOG4105K46	50S ribosomal protein l27
EGM51_10070	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
EGM51_10115	ENOG4108YZY	peptidylprolyl cis-trans isomerase
EGM51_10120	ENOG4105CBX	hi0933 family
EGM51_10145	ENOG4105CGD	Nad-dependent epimerase dehydratase
EGM51_10160	ENOG41072GX	Peptidase M22 Glycoprotease
EGM51_10165	ENOG4105K8N	protein family UPF0079, ATPase
EGM51_10170	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
EGM51_10175	ENOG4107SDT	Homocitrate synthase
EGM51_10180	ENOG4108JUA	Transcriptional regulator
EGM51_10190	ENOG4105M0C	cytoplasmic protein
EGM51_10195	ENOG4105DJ0	Poly(A) Polymerase
EGM51_10200	ENOG4108JUA	Transcriptional regulator
EGM51_10205	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
EGM51_10225	ENOG4105BZW	Glycerate kinase
EGM51_10230	ENOG41060NJ	transcriptional regulator
EGM51_10240	ENOG4105E0A	ABC, transporter
EGM51_10245	ENOG4105EHG	Permease protein
EGM51_10250	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
EGM51_10255	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
EGM51_10265	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
EGM51_10280	ENOG4105CNU	cell division protein FtsK
EGM51_10285	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
EGM51_10295	ENOG4108IJ2	phosphate acetyltransferase
EGM51_10300	ENOG4108ZT0	50S ribosomal protein l17
EGM51_10305	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
EGM51_10310	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
EGM51_10315	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EGM51_10325	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
EGM51_10330	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
EGM51_10340	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
EGM51_10345	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
EGM51_10350	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
EGM51_10355	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
EGM51_10360	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
EGM51_10365	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
EGM51_10370	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EGM51_10375	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
EGM51_10380	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
EGM51_10390	ENOG41082SA	50s ribosomal protein l29
EGM51_10395	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
EGM51_10400	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
EGM51_10405	ENOG41080P9	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
EGM51_10410	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
EGM51_10415	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EGM51_10420	ENOG41080UE	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
EGM51_10425	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
EGM51_10430	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
EGM51_10435	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
EGM51_10440	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
EGM51_10445	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
EGM51_10450	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
EGM51_10455	ENOG4105VEQ	Cold shock protein
EGM51_10470	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
EGM51_10475	ENOG4107QR0	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
EGM51_10480	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
EGM51_10485	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
EGM51_10495	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
EGM51_10500	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
EGM51_10505	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
EGM51_10520	ENOG41084ED	50S ribosomal protein L33
EGM51_10525	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
EGM51_10535	ENOG4107QHF	type ii secretion system protein e
EGM51_10555	ENOG4107VJY	DNA polymerase
EGM51_10740	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
EGM51_10785	ENOG4105BZU	Histidine kinase
EGM51_10790	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
EGM51_10795	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
EGM51_10805	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
EGM51_10810	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
EGM51_10820	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
EGM51_10830	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
EGM51_10835	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
EGM51_10855	ENOG4105CJ1	ABC, transporter
EGM51_10870	ENOG4105MYT	Heat shock protein
EGM51_10880	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
EGM51_10890	ENOG4105C3G	gtp-binding protein
EGM51_10895	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
EGM51_10910	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
EGM51_10915	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
EGM51_10930	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
EGM51_10955	ENOG4105DKW	ABC transporter
EGM51_10970	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
EGM51_10980	ENOG4108URH	decarboxylase
EGM51_10995	ENOG4105D0M	Protease HtpX homolog
EGM51_11000	ENOG4105FA0	parb-like partition protein
EGM51_11020	ENOG4108UVJ	appr-1-p processing domain protein
EGM51_11035	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
EGM51_11050	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
EGM51_11065	ENOG4105EPC	oxidoreductase
EGM51_11075	ENOG4107QTF	adenylosuccinate lyase
EGM51_11080	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
EGM51_11090	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
EGM51_11110	ENOG4105C1J	atp-dependent rna helicase
EGM51_11115	ENOG4105DC1	bifunctional purine biosynthesis protein purh
EGM51_11120	ENOG4108UT2	hemolysin iii
EGM51_11125	ENOG4107YV3	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
EGM51_11130	ENOG4105CAG	UPF0210 protein
EGM51_11135	ENOG4105VUC	UPF0237 protein
EGM51_11165	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
EGM51_11170	ENOG4105C4M	(Ubiquinol oxidase) subunit I
EGM51_11175	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
EGM51_11245	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
EGM51_11260	ENOG4105BZ8	glutamate synthase
EGM51_11275	ENOG4108Z4K	mutator MutT protein
EGM51_11300	ENOG4105CGK	Exodeoxyribonuclease III
EGM51_11305	ENOG4107QX9	Thiol disulfide interChange protein
EGM51_11315	ENOG4105CX6	glutaminyL-tRNA synthetase
EGM51_11325	ENOG4105C2W	permease
EGM51_11330	ENOG4105BZM	domain protein
EGM51_11345	ENOG4107S0N	DJ-1 family
EGM51_11355	ENOG4105E6M	Sulphatase-modifying factor protein
EGM51_11360	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
EGM51_11365	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
EGM51_11375	ENOG4105CDH	Citrulline--aspartate ligase
EGM51_11385	ENOG4105C8Y	Acetylornithine aminotransferase
EGM51_11390	ENOG4105CAS	nag kinase
EGM51_11395	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
EGM51_11400	ENOG4108UJD	30S ribosomal protein S9
EGM51_11405	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
EGM51_11415	ENOG4105BZU	Histidine kinase
EGM51_11440	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
EGM51_11450	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
EGM51_11460	ENOG4105DF0	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) (By similarity)
EGM51_11465	ENOG4107RY0	Catalyzes the conversion of dihydroorotate to orotate (By similarity)
EGM51_11515	ENOG4105D9P	serine threonine protein kinase
EGM51_11525	ENOG4107QI1	Mate efflux family protein
EGM51_11535	ENOG4105G6Z	alkaline phosphatase
EGM51_11575	ENOG4105Y49	secretion protein, HlyD family
EGM51_11580	ENOG4105BZS	acriflavin resistance protein
EGM51_11585	ENOG4105UQX	Mate efflux family protein
EGM51_11595	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
EGM51_11600	ENOG4105DSJ	YicC domain protein
EGM51_11665	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
EGM51_11675	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
EGM51_11680	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
EGM51_11685	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
EGM51_11690	ENOG4105DF3	Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta-cleavage pathway for the degradation of aromatic compounds (By similarity)
EGM51_11700	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
EGM51_11705	ENOG4105GYT	Protein of unknown function (DUF1009)
EGM51_11730	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
EGM51_11745	ENOG4105DEI	Mannitol dehydrogenase
EGM51_11760	ENOG4105ETE	Transcriptional regulator (LacI family
EGM51_11825	ENOG4105CIH	Imidazole acetol-phosphate transaminase
EGM51_11840	ENOG4105FR9	TRNA-(Ms 2 io 6 A)-hydroxylase
EGM51_11845	ENOG4105DP0	ferredoxin-NADP reductase
EGM51_11850	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
EGM51_11870	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
EGM51_11880	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
EGM51_11885	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
EGM51_11890	ENOG4105CFG	Acts as a chaperone (By similarity)
EGM51_11900	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
EGM51_11920	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
EGM51_11925	ENOG4108R96	Methyltransferase, YaeB family
EGM51_11930	ENOG4105E7U	AraC family transcriptional regulator
EGM51_11945	ENOG4105D0H	Alpha-glucuronidase (EC 3.2.1.139)
EGM51_11950	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
EGM51_11955	ENOG4105XDZ	Tripartite ATP-independent periplasmic transporter
EGM51_11960	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
EGM51_11965	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
EGM51_11980	ENOG4105D50	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate (By similarity)
EGM51_11985	ENOG4105F5H	Glycosyl Hydrolase Family 88
EGM51_12020	ENOG4105BZU	Histidine kinase
EGM51_12025	ENOG4105WH1	Two component transcriptional regulator luxr family
EGM51_12065	ENOG4107GFK	fumarate
EGM51_12095	ENOG4108KQ5	Integrase catalytic subunit
EGM51_12115	ENOG4105DSM	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components the iron protein and the molybdenum-iron protein (By similarity)
EGM51_12125	ENOG4108YZA	Nitrogen regulatory protein pii
EGM51_12160	ENOG4105CGC	Nitrogenase cofactor biosynthesis protein NifB
EGM51_12185	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
EGM51_12195	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
EGM51_12205	ENOG4105E0C	molybdate abc transporter
EGM51_12210	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
EGM51_12220	ENOG4105F0V	Cell wall hydrolase
EGM51_12235	ENOG41074MP	UPF0103 Mediator of ErbB2-driven cell motility-containing protein
EGM51_12325	ENOG4105CFI	type iii restriction protein res subunit
EGM51_12375	ENOG4105KPY	Small multidrug resistance protein
EGM51_12380	ENOG4105E6M	Sulphatase-modifying factor protein
EGM51_12395	ENOG4105C0D	helicase
EGM51_12430	ENOG4105CVR	type I restriction-modification system
EGM51_12440	ENOG4107HQ7	repeat protein
EGM51_12455	ENOG4106HBX	Transcriptional Regulator AraC Family
EGM51_12460	ENOG4105C0H	protease
EGM51_12465	ENOG4108VAU	general secretion pathway protein G
EGM51_12470	ENOG4108VAU	general secretion pathway protein G
EGM51_12475	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
EGM51_12480	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
EGM51_12490	ENOG41085KW	ppic-type peptidyL-prolyl cis-trans isomerase
EGM51_12500	ENOG4108V06	Glutathione peroxidase
EGM51_12545	ENOG4105CY0	Metallo-Beta-Lactamase
EGM51_12555	ENOG4105CHM	Aminotransferase
EGM51_12560	ENOG4108ZB6	transcriptional regulator AsnC family
EGM51_12585	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
EGM51_12590	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
EGM51_12595	ENOG4105MJ2	Competence protein
EGM51_12605	ENOG4105F8V	Hydrolase, tatD family
EGM51_12655	ENOG4105C0P	Mg chelatase subunit ChlI
EGM51_12665	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
EGM51_12675	ENOG4105M08	Membrane
EGM51_12690	ENOG4105FJH	Di-iron-containing protein involved in the repair of iron-sulfur clusters damaged by oxidative and nitrosative stress conditions (By similarity)
EGM51_12695	ENOG4105K78	MarR family Transcriptional regulator
EGM51_12705	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
EGM51_12710	ENOG4105C3N	Participates in control of cell volume in low-osmolarity conditions (By similarity)
EGM51_12720	ENOG4105BZU	Histidine kinase
EGM51_12725	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
EGM51_12730	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
EGM51_12740	ENOG4105NXH	GreA GreB family elongation factor
EGM51_12750	ENOG4105NXH	GreA GreB family elongation factor
EGM51_12765	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
EGM51_12770	ENOG4105HEE	Binding Domain protein
EGM51_12780	ENOG4105CKB	glycosidase
EGM51_12805	ENOG4108UXE	Protein tyrosine phosphatase
EGM51_12810	ENOG4105D6J	arsenicaL-resistance protein
EGM51_12865	ENOG4107TV1	YD repeat protein
EGM51_12895	ENOG4108YZA	Nitrogen regulatory protein pii
EGM51_12925	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
EGM51_12930	ENOG4105D4P	Coproporphyrinogen iii oxidase
EGM51_12935	ENOG4105C1Q	protoporphyrinogen oxidase
EGM51_12940	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
EGM51_12945	ENOG4105E5G	Alpha beta hydrolase fold
EGM51_12955	ENOG4108EE5	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
EGM51_12960	ENOG410624X	efflux transporter, rnd family, mfp subunit
EGM51_12980	ENOG4105DA6	Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity)
EGM51_12985	ENOG4105PFA	Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity)
EGM51_12990	ENOG4105DUM	transcriptional regulator, lysR family
EGM51_13005	ENOG4105KVH	Transcriptional regulator
EGM51_13020	ENOG4105ND9	Nitrogenase-associated protein
EGM51_13025	ENOG4105C8Y	Acetylornithine aminotransferase
EGM51_13055	ENOG4107R3N	Filamentation induced by cAMP protein fic
EGM51_13085	ENOG4105DZR	Type I site-specific deoxyribonuclease
EGM51_13105	ENOG4108IFG	nitrite reductase, (NAD(P)H)
EGM51_13115	ENOG4108Z03	MAF-like protein
EGM51_13130	ENOG4105BZU	Histidine kinase
EGM51_13165	ENOG4106QJH	hemin transport protein
EGM51_13175	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
EGM51_13190	ENOG41084EF	Ferredoxin
EGM51_13195	ENOG4105D4P	Coproporphyrinogen iii oxidase
EGM51_13215	ENOG4105ECQ	AraC Family Transcriptional Regulator
EGM51_13235	ENOG4109015	Biopolymer transport protein exbD tolR
EGM51_13260	ENOG41084EF	Ferredoxin
EGM51_13275	ENOG4109015	Biopolymer transport protein exbD tolR
EGM51_13295	ENOG4105E0A	ABC, transporter
EGM51_13305	ENOG4105CPC	Aldo Keto reductase
EGM51_13310	ENOG4105C7B	Threonine dehydratase
EGM51_13350	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
EGM51_13400	ENOG4105CDJ	oxidoreductase FAD NAD(P)-binding domain protein
EGM51_13405	ENOG4105BZ8	glutamate synthase
EGM51_13410	ENOG4105BZ8	glutamate synthase
EGM51_13435	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
EGM51_13450	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EGM51_13455	ENOG4105CZG	Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity)
EGM51_13465	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EGM51_13470	ENOG4105D8V	Glucose sorbosone dehydrogenase
EGM51_13475	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
EGM51_13490	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
EGM51_13525	ENOG4107QMH	DNA methylase
EGM51_13545	ENOG4105EMU	Dehydrogenase
EGM51_13570	ENOG4105CA9	Pyruvate kinase
EGM51_13575	ENOG4105BZ1	(ABC) transporter
EGM51_13605	ENOG4105J4Q	Transcriptional regulator
EGM51_13625	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
EGM51_13635	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
EGM51_13650	ENOG4107S2Z	UPF0761 membrane protein
EGM51_13660	ENOG4105C01	Dihydroxy-acid dehydratase
EGM51_13670	ENOG4108FN7	Aldo keto reductase
EGM51_13685	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
EGM51_13690	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
EGM51_13695	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
EGM51_13700	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
EGM51_13720	ENOG4105D7N	magnesium and cobalt transport protein CorA
EGM51_13735	ENOG4105CTQ	phosphohexokinase
EGM51_13745	ENOG41082K6	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
EGM51_13760	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
EGM51_13785	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
EGM51_13790	ENOG4105E1F	short-chain dehydrogenase reductase
EGM51_13800	ENOG4105BZU	Histidine kinase
EGM51_13805	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
EGM51_13815	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
EGM51_13820	ENOG4105BZU	Histidine kinase
EGM51_13835	ENOG4107YZX	Universal stress protein
EGM51_13840	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
EGM51_13900	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
EGM51_13905	ENOG4108UMZ	Cdp-alcohol phosphatidyltransferase
EGM51_13910	ENOG4108HPI	phosphatidate Cytidylyltransferase
EGM51_13935	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
EGM51_13940	ENOG4105VN1	Heat shock protein
EGM51_13960	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
EGM51_13965	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
EGM51_14025	ENOG41084HI	prevent-host-death family
EGM51_14040	ENOG4105DWY	Agmatine deiminase
EGM51_14055	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
EGM51_14065	ENOG41077A9	carbonic anhydrase
EGM51_14080	ENOG4105CHH	sulfate transporter
EGM51_14085	ENOG4108J9M	Transporter
EGM51_14105	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
EGM51_14115	ENOG4105D1F	ATP-binding protein
EGM51_14130	ENOG4105D1F	ATP-binding protein
EGM51_14145	ENOG4105VYW	UPF0251 protein
EGM51_14155	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
EGM51_14160	ENOG4105C0B	DNA polymerase III (alpha subunit)
EGM51_14170	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
EGM51_14180	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
EGM51_14200	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
EGM51_14205	ENOG4105CS2	ec 3.2.1.21
EGM51_14210	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
EGM51_14225	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
EGM51_14240	ENOG4105BZU	Histidine kinase
EGM51_14265	ENOG410810Y	Sulfite reductase
EGM51_14270	ENOG410834F	Transcriptional regulator
EGM51_14280	ENOG4105EUZ	Beta-lactamase domain protein
EGM51_14295	ENOG4107BMA	Transglycosylase associated protein
EGM51_14320	ENOG4105CNW	domain protein
EGM51_14325	ENOG4105UFH	BadM Rrf2 family transcriptional regulator
EGM51_14330	ENOG4105BZ1	(ABC) transporter
EGM51_14335	ENOG4105CGF	Aromatic amino acid aminotransferase
EGM51_14385	ENOG4105D0C	transport protein
EGM51_14395	ENOG4108KDD	Involved in the transport of maltose and maltodextrins (By similarity)
EGM51_14405	ENOG4107RUZ	Sss sodium solute transporter superfamily
EGM51_14410	ENOG4105ETE	Transcriptional regulator (LacI family
EGM51_14420	ENOG4105EN6	Membrane
EGM51_14430	ENOG4105CNT	hydrolase family 2
EGM51_14440	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
EGM51_14445	ENOG4108V0P	LemA family
EGM51_14480	ENOG4105BZU	Histidine kinase
EGM51_14490	ENOG4107TTQ	Alpha beta hydrolase fold
EGM51_14520	ENOG4105CVG	Homoserine O-transsuccinylase
EGM51_14555	ENOG4108XNJ	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
EGM51_14560	ENOG4105E8T	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG (By similarity)
EGM51_14565	ENOG4108YH3	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
EGM51_14570	ENOG4105CQM	Urea amidohydrolase subunit alpha
EGM51_14585	ENOG4108IV0	ABC, transporter
EGM51_14590	ENOG4105C0Z	ABC transporter
EGM51_14600	ENOG4105C32	Amino acid ABC transporter (Permease)
EGM51_14605	ENOG41083Z3	extracellular ligand-binding receptor
EGM51_14640	ENOG4105X5Z	General secretion pathway protein I
EGM51_14655	ENOG4105D7Q	type ii secretion system
EGM51_14660	ENOG4107QHF	type ii secretion system protein e
EGM51_14665	ENOG4105GVR	general secretion pathway protein D
EGM51_14675	ENOG4105K59	histidine triad (HIT) protein
EGM51_14690	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
EGM51_14695	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
EGM51_14725	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
EGM51_14745	ENOG4105C8B	TIGR00159 family
EGM51_14755	ENOG4108H5C	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
EGM51_14770	ENOG4107QZ7	Cellulose synthase catalytic subunit
EGM51_14775	ENOG4105EAY	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
EGM51_14790	ENOG4108BRW	Activates expression of the rhaSR operon in response to L-rhamnose (By similarity)
EGM51_14795	ENOG4105CMG	Carbohydrate kinase
EGM51_14800	ENOG4105C93	Xylose Isomerase
EGM51_14835	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
EGM51_14860	ENOG4105D9R	oxidoreductase
EGM51_14915	ENOG4105PW4	Sugar fermentation stimulation protein homolog
EGM51_14945	ENOG4108Z0R	Transferase
EGM51_14960	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
EGM51_14965	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
EGM51_14980	ENOG4107YDW	inorganic pyrophosphatase EC 3.6.1.1
EGM51_14985	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
EGM51_15000	ENOG4107WJT	it plays a direct role in the translocation of protons across the membrane (By similarity)
EGM51_15010	ENOG4108KJP	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
EGM51_15015	ENOG4107YZM	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
EGM51_15025	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
EGM51_15030	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
EGM51_15035	ENOG4107ZDE	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
EGM51_15045	ENOG4105K70	DNA-binding protein
EGM51_15070	ENOG4105CUZ	uba thif-type nad fad binding protein
EGM51_15085	ENOG4108JMX	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
EGM51_15090	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
EGM51_15095	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
EGM51_15105	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
EGM51_15140	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
EGM51_15145	ENOG4105D0M	Protease HtpX homolog
EGM51_15150	ENOG4108V0P	LemA family
EGM51_15155	ENOG4105K70	DNA-binding protein
EGM51_15175	ENOG4105C2J	ABC transporter
EGM51_15240	ENOG4108UW5	maltose o-acetyltransferase
EGM51_15270	ENOG4105DFA	alanine racemase domain protein
EGM51_15275	ENOG4105II7	pyrroline-5-carboxylate reductase
EGM51_15330	ENOG4105CHV	Transcription elongation factor NusA
EGM51_15335	ENOG4107EEM	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
EGM51_15345	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
EGM51_15355	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
EGM51_15370	ENOG4105DK0	Indole-3-glycerol phosphate synthase
EGM51_15390	ENOG4105GVR	general secretion pathway protein D
EGM51_15395	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
EGM51_15405	ENOG4105E0X	reductase
EGM51_15410	ENOG4108WQI	RNA Polymerase
EGM51_15440	ENOG4108KQ5	Integrase catalytic subunit
EGM51_15475	ENOG4105M8K	biopolymer transport protein
EGM51_15485	ENOG4109015	Biopolymer transport protein exbD tolR
EGM51_15505	ENOG4105CPP	Dehydrogenase, E1 component
EGM51_15530	ENOG4105EMY	transcriptional regulator
EGM51_15535	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
EGM51_15550	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EGM51_15560	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
EGM51_15570	ENOG4105VRT	cytoplasmic protein
EGM51_15590	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
EGM51_15605	ENOG4105BZ1	(ABC) transporter
EGM51_15625	ENOG4105ETX	regulatoR
EGM51_15630	ENOG4105BZU	Histidine kinase
EGM51_15645	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
EGM51_15650	ENOG4108NEV	two component transcriptional regulator, LytTR family
EGM51_15680	ENOG4105BZU	Histidine kinase
EGM51_15690	ENOG4105BZU	Histidine kinase
EGM51_15695	ENOG4105CQZ	Histidine kinase
EGM51_15705	ENOG4105C03	ribonuclease
EGM51_15710	ENOG4105CNI	cell division protein FtsW
EGM51_15715	ENOG4105CJN	penicillin-binding protein
EGM51_15775	ENOG4105D0S	secretion protein (HlyD
EGM51_15805	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
EGM51_15815	ENOG4105CBX	hi0933 family
EGM51_15840	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EGM51_15845	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
EGM51_15855	ENOG4107QJE	Chromosome Partitioning Protein
EGM51_15880	ENOG4105EPC	oxidoreductase
EGM51_15890	ENOG4105BZU	Histidine kinase
EGM51_15910	ENOG4107QRH	Arylsulfatase (Ec 3.1.6.1)
EGM51_15920	ENOG41061MV	Arylsulfatase
EGM51_15955	ENOG4105CNT	hydrolase family 2
EGM51_15960	ENOG4105ECQ	AraC Family Transcriptional Regulator
EGM51_15985	ENOG4105ESV	Glycosyl transferase, family 4
EGM51_15990	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
EGM51_15995	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
EGM51_16005	ENOG4106H78	methyltransferase
EGM51_16010	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
EGM51_16015	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
EGM51_16025	ENOG4105CC5	ABC transporter
EGM51_16030	ENOG4105DIK	(ABC) transporter
EGM51_16040	ENOG4108P3C	
EGM51_16060	ENOG4105C5H	ABC transporter
EGM51_16105	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
EGM51_16135	ENOG4105VDM	plasmid maintenance system antidote protein, xre family
EGM51_16160	ENOG4105K63	Thioredoxin
EGM51_16170	ENOG4105D3R	alkyl hydroperoxide reductase
EGM51_16190	ENOG4105CQ7	ATP-dependent helicase
EGM51_16195	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
EGM51_16205	ENOG4105CEY	Amp-dependent synthetase and ligase
EGM51_16225	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
EGM51_16230	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
EGM51_16240	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
EGM51_16245	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
EGM51_16255	ENOG4105Y7X	Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. Acts in DNA repair (By similarity)
EGM51_16260	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
EGM51_16300	ENOG4105C0D	helicase
EGM51_16305	ENOG4105EYH	Exonuclease
EGM51_16330	ENOG4105D52	delta-aminolevulinic acid dehydratase
EGM51_16335	ENOG4105DUN	Mediates zinc uptake. May also transport other divalent cations (By similarity)
EGM51_16345	ENOG4105IJJ	transcriptional regulator, crp fnr family
EGM51_16370	ENOG4105CPN	adenine deaminase
EGM51_16380	ENOG4105CSM	endonuclease III
EGM51_16390	ENOG4105ECY	inositol monophosphatase
EGM51_16400	ENOG4105DI5	UPF0365 protein
EGM51_16410	ENOG4105F7J	membrane-bound serine protease
EGM51_16420	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
EGM51_16430	ENOG4107RZC	phospholipase d
EGM51_16440	ENOG4105F8V	Hydrolase, tatD family
EGM51_16460	ENOG4105CNU	cell division protein FtsK
EGM51_16475	ENOG4108V1T	peptidylprolyl cis-trans isomerase
EGM51_16485	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
EGM51_16490	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
EGM51_16520	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
EGM51_16525	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
EGM51_16530	ENOG4105CI3	gtp-binding protein typa
EGM51_16535	ENOG4105VFU	Rna-binding protein
EGM51_16580	ENOG4108TVJ	Nitroreductase
EGM51_16585	ENOG4108RCM	Nitroreductase
EGM51_16590	ENOG4108WUH	Transcriptional regulator, TetR family
EGM51_16625	ENOG4108W8W	CRISPR-associated RAMP protein, Csm3 family
EGM51_16665	ENOG4105KCF	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease (By similarity)
EGM51_16705	ENOG4105CFP	Peptidase U32
EGM51_16710	ENOG4105D41	biosynthesis protein thiH
EGM51_16715	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
EGM51_16720	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
EGM51_16735	ENOG4105E02	MotA TolQ exbB proton channel
EGM51_16740	ENOG4105SG9	biopolymer transport protein, ExbD
EGM51_16750	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
EGM51_16755	ENOG4105KCK	Peptidoglycan-associated lipoprotein
EGM51_16765	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
EGM51_16770	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
EGM51_16775	ENOG4105CTQ	phosphohexokinase
EGM51_16780	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
EGM51_16800	ENOG4105JKW	Valine--pyruvate aminotransferase
EGM51_16810	ENOG41082YX	Transcriptional regulator, arsr family
EGM51_16840	ENOG4107Z6I	Thiamine biosynthesis protein
EGM51_16855	ENOG4105MRR	Transcriptional regulator (By similarity)
EGM51_16865	ENOG4105EIG	urea carboxylase-associated protein 1
EGM51_16880	ENOG4107RUE	extracellular solute-binding protein family 1
EGM51_16890	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
EGM51_16895	ENOG4105F38	ABC transporter, permease
EGM51_16900	ENOG4108EG7	Binding-protein-dependent transport systems, inner membrane component
EGM51_16910	ENOG410814C	multidrug resistance protein
EGM51_16915	ENOG4105DWY	Agmatine deiminase
EGM51_16920	ENOG4108JPW	Aminotransferase
EGM51_16925	ENOG4105C0A	alcohol dehydrogenase
EGM51_16930	ENOG4105C26	Dehydrogenase
EGM51_16950	ENOG4105E3Q	saccharopine dehydrogenase
EGM51_16970	ENOG4105C28	cystathionine
EGM51_16980	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
EGM51_17035	ENOG4105E3H	phosphoglycerate mutase
EGM51_17065	ENOG4105DJV	ribulose-phosphate 3-epimerase
EGM51_17090	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
EGM51_17095	ENOG4105CH7	arginosuccinase
EGM51_17115	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
EGM51_17120	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
EGM51_17125	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
EGM51_17135	ENOG4108UUM	single-stranded DNA-binding protein
EGM51_17140	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
EGM51_17145	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
EGM51_17150	ENOG4105CDU	Replicative dna helicase
EGM51_17155	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EGM51_17165	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
EGM51_17170	ENOG4105C2N	RNA methyltransferase TrmH family group 3
EGM51_17235	ENOG4105C31	Tryptophanyl-tRNA synthetase
EGM51_17245	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
EGM51_17250	ENOG4105CQC	Prephenate dehydratase
EGM51_17260	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
EGM51_17265	ENOG4105E2X	shikimate dehydrogenase
EGM51_17300	ENOG4107QHF	type ii secretion system protein e
EGM51_17305	ENOG4107QHF	type ii secretion system protein e
EGM51_17310	ENOG4105BZU	Histidine kinase
EGM51_17315	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
EGM51_17330	ENOG4105F8V	Hydrolase, tatD family
EGM51_17350	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
EGM51_17360	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
EGM51_17370	ENOG4105D48	metallophosphoesterase
EGM51_17375	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
EGM51_17400	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
EGM51_17405	ENOG4105CEV	competence damage-inducible protein
EGM51_17420	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
EGM51_17425	ENOG4105EMN	RNA polymerase sigma factor
EGM51_17435	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
EGM51_17440	ENOG4107WAU	Protein tyrosine phosphatase
EGM51_17450	ENOG4105C25	Primosomal protein n'
EGM51_17465	ENOG4105FS0	cytoplasmic membrane protein
EGM51_17475	ENOG4105C2X	Arabinose 5-phosphate isomerase
EGM51_17485	ENOG4108FKR	NLP P60 protein
EGM51_17500	ENOG4105C5I	Dehydrogenase
EGM51_17505	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
EGM51_17510	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
EGM51_17515	ENOG4105CDY	transcriptional regulatory protein
EGM51_17525	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
EGM51_17540	ENOG4108RAC	Rubrerythrin
EGM51_17550	ENOG4105CBC	glutamate synthase
EGM51_17575	ENOG4108JU3	Alkyl hydroperoxide reductase
EGM51_17580	ENOG4105D3R	alkyl hydroperoxide reductase
EGM51_17600	ENOG4105D49	3-dehydroquinate synthase
EGM51_17610	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
EGM51_17615	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
EGM51_17665	ENOG4107RMF	Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes (By similarity)
EGM51_17675	ENOG4105DTZ	bifunctional PTS system fructose-specific transporter subunit IIA HPr protein
EGM51_17680	ENOG4105D2N	Aldolase
EGM51_17700	ENOG4108FUF	Transcriptional regulator, IclR family
EGM51_17725	ENOG4107SYN	Glycosyl hydrolases family 43
EGM51_17730	ENOG4107SYN	Glycosyl hydrolases family 43
EGM51_17735	ENOG4105D0H	Alpha-glucuronidase (EC 3.2.1.139)
EGM51_17765	ENOG4106AM8	polysaccharide lyase family 8
EGM51_17800	ENOG41061MV	Arylsulfatase
EGM51_17820	ENOG41062D9	Histidine kinase
EGM51_17825	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
EGM51_17845	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
EGM51_17895	ENOG4106855	Competence protein
EGM51_17900	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
EGM51_17905	ENOG4105D7Q	type ii secretion system
EGM51_17910	ENOG4107QHF	type ii secretion system protein e
EGM51_17950	ENOG4105E4G	Type IV pilus
EGM51_17970	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
EGM51_17980	ENOG4108YYC	ycei family
EGM51_17985	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
EGM51_18005	ENOG4105DVT	helicase
EGM51_18010	ENOG4105IIU	Aminopeptidase
EGM51_18015	ENOG4107VAM	peptidase, m28
EGM51_18020	ENOG4107VAM	peptidase, m28
EGM51_18030	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
EGM51_18045	ENOG4105CRE	cytochrome C
EGM51_18050	ENOG4105BZU	Histidine kinase
EGM51_18055	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
EGM51_18065	ENOG4108ZZ3	UPF0260 protein