locus-tag	class	description
MM50RIKEN_-0030	COG1674	ftsk spoiiie
MM50RIKEN_-0030	COG4980	gas vesicle protein
MM50RIKEN_00010	COG0686	Belongs to the AlaDH PNT family
MM50RIKEN_00020	COG0686	Belongs to the AlaDH PNT family
MM50RIKEN_00040	COG1757	Na H antiporter
MM50RIKEN_00050	COG0686	Belongs to the AlaDH PNT family
MM50RIKEN_00110	COG1921	L-seryl-tRNASec selenium transferase activity
MM50RIKEN_00220	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MM50RIKEN_00230	COG0459	protein refolding
MM50RIKEN_00240	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MM50RIKEN_00250	COG1597	lipid kinase activity
MM50RIKEN_00260	COG0116	Belongs to the methyltransferase superfamily
MM50RIKEN_00270	COG1725	Transcriptional regulator
MM50RIKEN_00300	COG1131	(ABC) transporter
MM50RIKEN_00360	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MM50RIKEN_00390	COG1098	S1 RNA binding domain
MM50RIKEN_00430	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
MM50RIKEN_00450	COG3956	TIGRFAM MazG family protein
MM50RIKEN_00460	COG2244	polysaccharide biosynthetic process
MM50RIKEN_00470	COG0635	Involved in the biosynthesis of porphyrin-containing compound
MM50RIKEN_00480	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MM50RIKEN_00490	COG1490	D-aminoacyl-tRNA deacylase activity
MM50RIKEN_00500	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MM50RIKEN_00510	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
MM50RIKEN_00510	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
MM50RIKEN_00530	COG1045	serine acetyltransferase
MM50RIKEN_00550	COG0295	cytidine deaminase activity
MM50RIKEN_00610	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
MM50RIKEN_00620	COG2188	Transcriptional regulator
MM50RIKEN_00630	COG0590	tRNA wobble adenosine to inosine editing
MM50RIKEN_00660	COG0037	tRNA processing
MM50RIKEN_00670	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MM50RIKEN_00730	COG0252	asparaginase activity
MM50RIKEN_00740	COG0420	3'-5' exonuclease activity
MM50RIKEN_00750	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MM50RIKEN_00760	COG1692	metallophosphoesterase
MM50RIKEN_00790	COG1418	mRNA catabolic process
MM50RIKEN_00830	COG1121	(ABC) transporter
MM50RIKEN_00840	COG1108	ABC-type Mn2 Zn2 transport systems permease components
MM50RIKEN_00850	COG0779	Required for maturation of 30S ribosomal subunits
MM50RIKEN_00860	COG0195	Participates in both transcription termination and antitermination
MM50RIKEN_00870	COG2740	Nucleic-acid-binding protein implicated in transcription termination
MM50RIKEN_00890	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MM50RIKEN_00900	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MM50RIKEN_00910	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
MM50RIKEN_00920	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MM50RIKEN_00930	COG0196	riboflavin kinase activity
MM50RIKEN_00950	COG0446	pyridine nucleotide-disulphide oxidoreductase
MM50RIKEN_00960	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MM50RIKEN_00970	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MM50RIKEN_00990	COG0322	excinuclease ABC activity
MM50RIKEN_01000	COG1376	ErfK ybiS ycfS ynhG family protein
MM50RIKEN_01010	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MM50RIKEN_01020	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
MM50RIKEN_01040	COG0668	transmembrane transport
MM50RIKEN_01050	COG0460	homoserine dehydrogenase
MM50RIKEN_01060	COG0460	homoserine dehydrogenase
MM50RIKEN_01190	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
MM50RIKEN_01200	COG0745	RESPONSE REGULATOR receiver
MM50RIKEN_01210	COG2205	protein histidine kinase activity
MM50RIKEN_01220	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
MM50RIKEN_01230	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
MM50RIKEN_01240	COG3475	LICD family
MM50RIKEN_01250	COG3475	LICD family
MM50RIKEN_01290	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
MM50RIKEN_01310	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MM50RIKEN_01330	COG1136	(ABC) transporter
MM50RIKEN_01330	COG0577	efflux transmembrane transporter activity
MM50RIKEN_01360	COG4716	Myosin-crossreactive antigen
MM50RIKEN_01380	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
MM50RIKEN_01440	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
MM50RIKEN_01470	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MM50RIKEN_01480	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MM50RIKEN_01500	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MM50RIKEN_01510	COG1773	rubredoxin
MM50RIKEN_01510	COG1592	Rubrerythrin
MM50RIKEN_01540	COG0726	polysaccharide deacetylase
MM50RIKEN_01550	COG0789	Transcriptional regulator
MM50RIKEN_01580	COG1295	ribonuclease BN
MM50RIKEN_01600	COG0617	tRNA 3'-terminal CCA addition
MM50RIKEN_01610	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
MM50RIKEN_01630	COG1304	FMN binding
MM50RIKEN_01640	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
MM50RIKEN_01670	COG3853	Toxic anion resistance protein (TelA)
MM50RIKEN_01720	COG0211	Belongs to the bacterial ribosomal protein bL27 family
MM50RIKEN_01740	COG0261	This protein binds to 23S rRNA in the presence of protein L20
MM50RIKEN_01770	COG1323	Belongs to the UPF0348 family
MM50RIKEN_01810	COG1051	belongs to the nudix hydrolase family
MM50RIKEN_01820	COG1683	Conserved Protein
MM50RIKEN_01900	COG0800	Aldolase
MM50RIKEN_01910	COG1312	Catalyzes the dehydration of D-mannonate
MM50RIKEN_01920	COG0246	Mannitol dehydrogenase
MM50RIKEN_01930	COG0765	amino acid transport
MM50RIKEN_01940	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MM50RIKEN_01990	COG1126	abc transporter atp-binding protein
MM50RIKEN_02000	COG1904	glucuronate isomerase
MM50RIKEN_02020	COG2721	sulfolactate sulfo-lyase activity
MM50RIKEN_02050	COG1136	(ABC) transporter
MM50RIKEN_02070	COG0577	efflux transmembrane transporter activity
MM50RIKEN_02120	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MM50RIKEN_02200	COG0215	cysteine-tRNA ligase activity
MM50RIKEN_02210	COG1396	sequence-specific DNA binding
MM50RIKEN_02240	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MM50RIKEN_02270	COG2890	protein-(glutamine-N5) methyltransferase activity
MM50RIKEN_02280	COG3872	metal-dependent enzyme
MM50RIKEN_02290	COG2205	protein histidine kinase activity
MM50RIKEN_02300	COG0745	RESPONSE REGULATOR receiver
MM50RIKEN_02360	COG0745	RESPONSE REGULATOR receiver
MM50RIKEN_02370	COG5002	protein histidine kinase activity
MM50RIKEN_02390	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MM50RIKEN_02430	COG1473	amidohydrolase
MM50RIKEN_02440	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MM50RIKEN_02450	COG4120	Belongs to the binding-protein-dependent transport system permease family
MM50RIKEN_02480	COG0768	penicillin binding
MM50RIKEN_02490	COG0772	Belongs to the SEDS family
MM50RIKEN_02530	COG0601	transmembrane transport
MM50RIKEN_02540	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MM50RIKEN_02550	COG0444	Belongs to the ABC transporter superfamily
MM50RIKEN_02560	COG4608	Belongs to the ABC transporter superfamily
MM50RIKEN_02580	COG1362	aminopeptidase activity
MM50RIKEN_02610	COG2226	methyltransferase
MM50RIKEN_02620	COG0534	Mate efflux family protein
MM50RIKEN_02630	COG1104	cysteine desulfurase activity
MM50RIKEN_02640	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MM50RIKEN_02650	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
MM50RIKEN_02660	COG0333	Belongs to the bacterial ribosomal protein bL32 family
MM50RIKEN_02680	COG0564	pseudouridine synthase activity
MM50RIKEN_02690	COG3842	ATPase activity
MM50RIKEN_02700	COG1176	ABC-type spermidine putrescine transport system, permease component I
MM50RIKEN_02710	COG1177	transmembrane transport
MM50RIKEN_02720	COG3830	Belongs to the UPF0237 family
MM50RIKEN_02730	COG2848	UPF0210 protein
MM50RIKEN_02740	COG1342	Belongs to the UPF0251 family
MM50RIKEN_02780	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MM50RIKEN_02800	COG3437	response regulator, receiver
MM50RIKEN_02850	COG0740	serine-type endopeptidase activity
MM50RIKEN_02890	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
MM50RIKEN_02890	COG1918	ferrous iron import across plasma membrane
MM50RIKEN_02990	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
MM50RIKEN_03010	COG3906	Belongs to the UPF0473 family
MM50RIKEN_03020	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
MM50RIKEN_03030	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MM50RIKEN_03040	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
MM50RIKEN_03050	COG0038	chloride channel
MM50RIKEN_03060	COG2323	membrane
MM50RIKEN_03070	COG2081	HI0933 family
MM50RIKEN_03080	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MM50RIKEN_03090	COG0267	Belongs to the bacterial ribosomal protein bL33 family
MM50RIKEN_03110	COG0250	Participates in transcription elongation, termination and antitermination
MM50RIKEN_03120	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MM50RIKEN_03130	COG0081	regulation of translation
MM50RIKEN_03140	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MM50RIKEN_03150	COG0222	ribosome binding
MM50RIKEN_03220	COG0335	large ribosomal subunit rRNA binding
MM50RIKEN_03230	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MM50RIKEN_03260	COG3655	Transcriptional regulator
MM50RIKEN_03270	COG0534	Mate efflux family protein
MM50RIKEN_03280	COG3854	ATPases associated with a variety of cellular activities
MM50RIKEN_03360	COG1302	Protein conserved in bacteria
MM50RIKEN_03380	COG1570	exodeoxyribonuclease VII activity
MM50RIKEN_03390	COG1722	exodeoxyribonuclease VII activity
MM50RIKEN_03440	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MM50RIKEN_03470	COG1131	(ABC) transporter
MM50RIKEN_03480	COG4472	Bacterial protein of unknown function (DUF965)
MM50RIKEN_03490	COG0072	phenylalanine-tRNA ligase activity
MM50RIKEN_03490	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MM50RIKEN_03530	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MM50RIKEN_03530	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
MM50RIKEN_03580	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
MM50RIKEN_03590	COG2323	membrane
MM50RIKEN_03610	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MM50RIKEN_03630	COG2337	Toxic component of a toxin-antitoxin (TA) module
MM50RIKEN_03660	COG5002	protein histidine kinase activity
MM50RIKEN_03670	COG0745	RESPONSE REGULATOR receiver
MM50RIKEN_03690	COG1686	Belongs to the peptidase S11 family
MM50RIKEN_03700	COG0564	pseudouridine synthase activity
MM50RIKEN_03750	COG2226	methyltransferase
MM50RIKEN_04080	COG0456	acetyltransferase
MM50RIKEN_04110	COG0740	serine-type endopeptidase activity
MM50RIKEN_04130	COG1309	transcriptional regulator
MM50RIKEN_04200	COG3617	BRO family, N-terminal domain
MM50RIKEN_04320	COG0791	NLP P60 protein
MM50RIKEN_04320	COG0741	lytic transglycosylase activity
MM50RIKEN_04350	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MM50RIKEN_04350	COG0551	DNA topoisomerase type I activity
MM50RIKEN_04430	COG4474	Belongs to the UPF0398 family
MM50RIKEN_04450	COG1199	ATP-dependent helicase activity
MM50RIKEN_04470	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
MM50RIKEN_04530	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
MM50RIKEN_04550	COG3843	relaxase mobilization nuclease domain protein
MM50RIKEN_04600	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MM50RIKEN_04620	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
MM50RIKEN_04700	COG3620	sequence-specific DNA binding
MM50RIKEN_04810	COG2226	methyltransferase
MM50RIKEN_04840	COG0733	neurotransmitter:sodium symporter activity
MM50RIKEN_04870	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
MM50RIKEN_04890	COG1363	Peptidase, m42
MM50RIKEN_04920	COG0697	spore germination
MM50RIKEN_04940	COG2190	(PTS) system
MM50RIKEN_04940	COG2211	Major facilitator Superfamily
MM50RIKEN_04960	COG0742	ribosomal rna small subunit methyltransferase
MM50RIKEN_04970	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MM50RIKEN_04990	COG2001	Belongs to the MraZ family
MM50RIKEN_05000	COG0275	rRNA processing
MM50RIKEN_05020	COG0768	penicillin binding
MM50RIKEN_05040	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MM50RIKEN_05050	COG0772	Belongs to the SEDS family
MM50RIKEN_05060	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MM50RIKEN_05070	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MM50RIKEN_05090	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MM50RIKEN_05140	COG3426	butyrate kinase activity
MM50RIKEN_05150	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
MM50RIKEN_05170	COG0156	8-amino-7-oxononanoate synthase activity
MM50RIKEN_05180	COG0300	oxidoreductase activity
MM50RIKEN_05190	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MM50RIKEN_05200	COG1592	Rubrerythrin
MM50RIKEN_05210	COG2116	formate transmembrane transporter activity
MM50RIKEN_05240	COG3340	Belongs to the peptidase S51 family
MM50RIKEN_05250	COG1301	dicarboxylic acid transport
MM50RIKEN_05310	COG2333	competence protein COMEC
MM50RIKEN_05310	COG0658	competence protein
MM50RIKEN_05340	COG2357	RelA SpoT domain protein
MM50RIKEN_05370	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MM50RIKEN_05380	COG0218	Necessary for normal cell division and for the maintenance of normal septation
MM50RIKEN_05390	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
MM50RIKEN_05400	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MM50RIKEN_05420	COG0544	peptidyl-prolyl cis-trans isomerase activity
MM50RIKEN_05450	COG0792	nuclease activity
MM50RIKEN_05460	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MM50RIKEN_05500	COG0326	Molecular chaperone. Has ATPase activity
MM50RIKEN_05540	COG0737	Belongs to the 5'-nucleotidase family
MM50RIKEN_05550	COG0493	'glutamate synthase
MM50RIKEN_05550	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
MM50RIKEN_05570	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MM50RIKEN_05580	COG1214	PFAM Peptidase M22, glycoprotease
MM50RIKEN_05590	COG0802	atpase or kinase
MM50RIKEN_05600	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
MM50RIKEN_05630	COG0641	radical SAM
MM50RIKEN_05640	COG1982	Orn Lys Arg decarboxylase major
MM50RIKEN_05660	COG0602	queuosine metabolic process
MM50RIKEN_05670	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MM50RIKEN_05670	COG1328	CTP reductase activity
MM50RIKEN_05690	COG1115	amino acid carrier protein
MM50RIKEN_05700	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MM50RIKEN_05720	COG1827	regulation of RNA biosynthetic process
MM50RIKEN_05750	COG2759	Belongs to the formate--tetrahydrofolate ligase family
MM50RIKEN_05760	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MM50RIKEN_05770	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MM50RIKEN_05790	COG0612	Peptidase, M16
MM50RIKEN_05800	COG0612	Peptidase, M16
MM50RIKEN_05810	COG0826	peptidase U32
MM50RIKEN_05840	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MM50RIKEN_05850	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
MM50RIKEN_05880	COG0233	cytoplasmic translational termination
MM50RIKEN_05900	COG4589	Belongs to the CDS family
MM50RIKEN_05910	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
MM50RIKEN_05920	COG0750	zinc metalloprotease
MM50RIKEN_05930	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
MM50RIKEN_05940	COG2176	DNA-directed DNA polymerase activity
MM50RIKEN_05950	COG2091	lysine biosynthetic process via aminoadipic acid
MM50RIKEN_05970	COG0052	Belongs to the universal ribosomal protein uS2 family
MM50RIKEN_05990	COG0227	Belongs to the bacterial ribosomal protein bL28 family
MM50RIKEN_06000	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
MM50RIKEN_06010	COG1940	carbohydrate kinase activity
MM50RIKEN_06030	COG1660	Displays ATPase and GTPase activities
MM50RIKEN_06050	COG1481	regulation of sporulation
MM50RIKEN_06160	COG0402	S-adenosylhomocysteine deaminase activity
MM50RIKEN_06180	COG2188	Transcriptional regulator
MM50RIKEN_06200	COG3845	ABC transporter
MM50RIKEN_06210	COG4603	Belongs to the binding-protein-dependent transport system permease family
MM50RIKEN_06250	COG0800	Aldolase
MM50RIKEN_06260	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MM50RIKEN_06270	COG0436	Aminotransferase
MM50RIKEN_06310	COG0582	viral genome integration into host DNA
MM50RIKEN_06330	COG0582	viral genome integration into host DNA
MM50RIKEN_06340	COG0572	uridine kinase
MM50RIKEN_06350	COG0237	dephospho-CoA kinase activity
MM50RIKEN_06360	COG4221	oxidoreductase activity
MM50RIKEN_06400	COG0456	acetyltransferase
MM50RIKEN_06570	COG1396	sequence-specific DNA binding
MM50RIKEN_06700	COG1164	Oligoendopeptidase f
MM50RIKEN_06710	COG1196	nuclear chromosome segregation
MM50RIKEN_06720	COG0552	protein localization to endoplasmic reticulum
MM50RIKEN_06730	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
MM50RIKEN_06740	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MM50RIKEN_06750	COG1534	Rna-binding protein
MM50RIKEN_06760	COG1713	HD superfamily hydrolase involved in NAD metabolism
MM50RIKEN_06770	COG0799	negative regulation of ribosome biogenesis
MM50RIKEN_06780	COG0495	leucyl-tRNA aminoacylation
MM50RIKEN_06800	COG0828	Belongs to the bacterial ribosomal protein bS21 family
MM50RIKEN_06820	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
MM50RIKEN_06830	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MM50RIKEN_06860	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
MM50RIKEN_06870	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
MM50RIKEN_06880	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
MM50RIKEN_06890	COG0297	glycogen (starch) synthase activity
MM50RIKEN_06900	COG0058	SHG alpha-glucan phosphorylase activity
MM50RIKEN_06910	COG0544	peptidyl-prolyl cis-trans isomerase activity
MM50RIKEN_06950	COG0493	'glutamate synthase
MM50RIKEN_06950	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
MM50RIKEN_07070	COG2205	protein histidine kinase activity
MM50RIKEN_07080	COG0745	RESPONSE REGULATOR receiver
MM50RIKEN_07110	COG0651	ATP synthesis coupled electron transport
MM50RIKEN_07120	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MM50RIKEN_07130	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
MM50RIKEN_07130	COG2111	Na H antiporter
MM50RIKEN_07140	COG0651	ATP synthesis coupled electron transport
MM50RIKEN_07200	COG1863	multisubunit Na H antiporter MnhE subunit
MM50RIKEN_07220	COG1696	Membrane protein involved in D-alanine export
MM50RIKEN_07250	COG1191	sigma factor activity
MM50RIKEN_07260	COG0822	iron-sulfur transferase activity
MM50RIKEN_07290	COG1293	RNA-binding protein homologous to eukaryotic snRNP
MM50RIKEN_07310	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MM50RIKEN_07320	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
MM50RIKEN_07330	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MM50RIKEN_07340	COG1438	arginine binding
MM50RIKEN_07350	COG0497	DNA recombination
MM50RIKEN_07360	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MM50RIKEN_07450	COG1074	ATP-dependent DNA helicase activity
MM50RIKEN_07460	COG0254	rRNA binding
MM50RIKEN_07470	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MM50RIKEN_07490	COG1739	Uncharacterized protein family UPF0029
MM50RIKEN_07530	COG2195	Cleaves the N-terminal amino acid of tripeptides
MM50RIKEN_07550	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
MM50RIKEN_07560	COG1160	GTP binding
MM50RIKEN_07570	COG0750	zinc metalloprotease
MM50RIKEN_07580	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
MM50RIKEN_07590	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MM50RIKEN_07600	COG0228	four-way junction DNA binding
MM50RIKEN_07610	COG1837	Belongs to the UPF0109 family
MM50RIKEN_07620	COG1164	Oligoendopeptidase f
MM50RIKEN_07640	COG3546	catalase activity
MM50RIKEN_07650	COG0205	6-phosphofructokinase activity
MM50RIKEN_07660	COG0191	fructose-bisphosphate aldolase activity
MM50RIKEN_07730	COG0772	Belongs to the SEDS family
MM50RIKEN_07750	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
MM50RIKEN_07760	COG0488	(ABC) transporter
MM50RIKEN_07780	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MM50RIKEN_07800	COG0009	L-threonylcarbamoyladenylate synthase
MM50RIKEN_07810	COG1362	aminopeptidase activity
MM50RIKEN_07840	COG0534	Mate efflux family protein
MM50RIKEN_07870	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
MM50RIKEN_07880	COG0632	four-way junction helicase activity
MM50RIKEN_07890	COG2255	four-way junction helicase activity
MM50RIKEN_07900	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MM50RIKEN_07940	COG2384	SAM-dependent methyltransferase
MM50RIKEN_07960	COG0217	transcriptional regulatory protein
MM50RIKEN_07980	COG3958	Transketolase
MM50RIKEN_07990	COG3959	Transketolase, thiamine diphosphate binding domain
MM50RIKEN_08000	COG4974	Belongs to the 'phage' integrase family
MM50RIKEN_08010	COG0860	N-Acetylmuramoyl-L-alanine amidase
MM50RIKEN_08020	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MM50RIKEN_08050	COG0210	DNA helicase
MM50RIKEN_08110	COG1876	peptidase activity
MM50RIKEN_08120	COG1181	Belongs to the D-alanine--D-alanine ligase family
MM50RIKEN_08370	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
MM50RIKEN_08390	COG2205	protein histidine kinase activity
MM50RIKEN_08400	COG0628	permease
MM50RIKEN_08410	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MM50RIKEN_08430	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MM50RIKEN_08580	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MM50RIKEN_08600	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
MM50RIKEN_08630	COG0583	DNA-binding transcription factor activity
MM50RIKEN_08640	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
MM50RIKEN_08650	COG1191	sigma factor activity
MM50RIKEN_08660	COG2172	sigma factor antagonist activity
MM50RIKEN_08670	COG1366	Belongs to the anti-sigma-factor antagonist family
MM50RIKEN_08680	COG0525	valine-tRNA ligase activity
MM50RIKEN_08700	COG0534	Mate efflux family protein
MM50RIKEN_08710	COG0539	negative regulation of cytoplasmic translation
MM50RIKEN_08710	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
MM50RIKEN_08730	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
MM50RIKEN_08740	COG2081	HI0933 family
MM50RIKEN_08760	COG1187	pseudouridine synthase activity
MM50RIKEN_08770	COG1686	Belongs to the peptidase S11 family
MM50RIKEN_08780	COG3874	Sporulation protein YtfJ
MM50RIKEN_08800	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MM50RIKEN_08820	COG1994	Peptidase M50
MM50RIKEN_08840	COG1191	sigma factor activity
MM50RIKEN_08860	COG4481	Protein conserved in bacteria
MM50RIKEN_08880	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
MM50RIKEN_08890	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MM50RIKEN_08940	COG4974	Belongs to the 'phage' integrase family
MM50RIKEN_08980	COG0343	queuine tRNA-ribosyltransferase activity
MM50RIKEN_09030	COG2155	Conserved Protein
MM50RIKEN_09040	COG0336	Belongs to the RNA methyltransferase TrmD family
MM50RIKEN_09060	COG3584	3D domain protein
MM50RIKEN_09100	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
MM50RIKEN_09110	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MM50RIKEN_09120	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MM50RIKEN_09130	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MM50RIKEN_09140	COG5290	Psort location Cytoplasmic, score
MM50RIKEN_09150	COG0582	viral genome integration into host DNA
MM50RIKEN_09360	COG1489	DNA binding
MM50RIKEN_09390	COG1393	Belongs to the ArsC family
MM50RIKEN_09460	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
MM50RIKEN_09480	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
MM50RIKEN_09490	COG0671	phosphoesterase, PA-phosphatase related
MM50RIKEN_09570	COG0656	L-ascorbic acid biosynthetic process
MM50RIKEN_09580	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MM50RIKEN_09590	COG0789	Transcriptional regulator
MM50RIKEN_09610	COG0622	Phosphoesterase
MM50RIKEN_09680	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MM50RIKEN_09690	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
MM50RIKEN_09700	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
MM50RIKEN_09720	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MM50RIKEN_09760	COG0444	Belongs to the ABC transporter superfamily
MM50RIKEN_09770	COG4608	Belongs to the ABC transporter superfamily
MM50RIKEN_09780	COG0601	transmembrane transport
MM50RIKEN_09790	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MM50RIKEN_09800	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
MM50RIKEN_09850	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MM50RIKEN_09860	COG1307	EDD domain protein, DegV family
MM50RIKEN_09970	COG1937	Protein conserved in bacteria
MM50RIKEN_09980	COG2217	Heavy metal translocating P-type atpase
MM50RIKEN_09990	COG4166	transmembrane transport
MM50RIKEN_10050	COG0527	aspartate kinase activity
MM50RIKEN_10060	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MM50RIKEN_10080	COG1136	(ABC) transporter
MM50RIKEN_10100	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MM50RIKEN_10110	COG0765	amino acid transport
MM50RIKEN_10120	COG1126	abc transporter atp-binding protein
MM50RIKEN_10150	COG1162	GTPase activity
MM50RIKEN_10160	COG0515	serine threonine protein kinase
MM50RIKEN_10160	COG2815	serine threonine protein kinase
MM50RIKEN_10170	COG0631	protein serine/threonine phosphatase activity
MM50RIKEN_10180	COG0820	rRNA (adenine-C2-)-methyltransferase activity
MM50RIKEN_10190	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MM50RIKEN_10190	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MM50RIKEN_10200	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MM50RIKEN_10220	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MM50RIKEN_10240	COG0194	GDP metabolic process
MM50RIKEN_10250	COG2052	Domain of unknown function (DUF370)
MM50RIKEN_10260	COG1561	YicC-like family, N-terminal region
MM50RIKEN_10270	COG0484	heat shock protein binding
MM50RIKEN_10310	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MM50RIKEN_10360	COG0515	serine threonine protein kinase
MM50RIKEN_10360	COG2815	serine threonine protein kinase
MM50RIKEN_10510	COG0582	viral genome integration into host DNA
MM50RIKEN_10580	COG2337	Toxic component of a toxin-antitoxin (TA) module
MM50RIKEN_10760	COG0629	single-stranded DNA binding
MM50RIKEN_10960	COG3859	Proton-coupled thiamine transporter YuaJ
MM50RIKEN_11040	COG0494	nUDIX hydrolase
MM50RIKEN_11050	COG1307	EDD domain protein, DegV family
MM50RIKEN_11070	COG1971	Probably functions as a manganese efflux pump
MM50RIKEN_11080	COG2502	aspartate--ammonia ligase
MM50RIKEN_11090	COG0436	Aminotransferase
MM50RIKEN_11100	COG3949	Membrane
MM50RIKEN_11120	COG1687	branched-chain amino acid
MM50RIKEN_11130	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
MM50RIKEN_11180	COG1011	Hydrolase
MM50RIKEN_11200	COG0542	response to heat
MM50RIKEN_11230	COG0101	tRNA pseudouridine synthase activity
MM50RIKEN_11240	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MM50RIKEN_11250	COG1122	ATPase activity
MM50RIKEN_11260	COG1122	ATPase activity
MM50RIKEN_11330	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
MM50RIKEN_11340	COG0427	acetyl-CoA hydrolase
MM50RIKEN_11350	COG0366	Alpha amylase catalytic
MM50RIKEN_11380	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MM50RIKEN_11410	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
MM50RIKEN_11420	COG0709	Synthesizes selenophosphate from selenide and ATP
MM50RIKEN_11430	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
MM50RIKEN_11430	COG3608	succinylglutamate desuccinylase aspartoacylase
MM50RIKEN_11450	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MM50RIKEN_11470	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
MM50RIKEN_11480	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
MM50RIKEN_11490	COG1329	Transcriptional regulator
MM50RIKEN_11500	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
MM50RIKEN_11550	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MM50RIKEN_11560	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MM50RIKEN_11570	COG0549	Belongs to the carbamate kinase family
MM50RIKEN_11590	COG3845	ABC transporter
MM50RIKEN_11610	COG1079	Belongs to the binding-protein-dependent transport system permease family
MM50RIKEN_11640	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
MM50RIKEN_11660	COG0564	pseudouridine synthase activity
MM50RIKEN_11700	COG0504	CTP synthase activity
MM50RIKEN_11720	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
MM50RIKEN_11730	COG1307	EDD domain protein, DegV family
MM50RIKEN_11750	COG1959	2 iron, 2 sulfur cluster binding
MM50RIKEN_11780	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
MM50RIKEN_11790	COG1529	Aldehyde oxidase and xanthine dehydrogenase
MM50RIKEN_11830	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MM50RIKEN_11840	COG0537	adenosine 5'-monophosphoramidase activity
MM50RIKEN_11870	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
MM50RIKEN_11880	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MM50RIKEN_11900	COG4475	Protein of unknown function (DUF436)
MM50RIKEN_11950	COG1960	acyl-CoA dehydrogenase activity
MM50RIKEN_11960	COG1250	3-hydroxyacyl-CoA dehydrogenase
MM50RIKEN_11970	COG1024	Enoyl-CoA hydratase
MM50RIKEN_11980	COG0220	tRNA (guanine-N7-)-methyltransferase activity
MM50RIKEN_11990	COG0426	domain, Protein
MM50RIKEN_11990	COG1773	rubredoxin
MM50RIKEN_12010	COG0291	Belongs to the bacterial ribosomal protein bL35 family
MM50RIKEN_12020	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MM50RIKEN_12050	COG1876	peptidase activity
MM50RIKEN_12080	COG1316	TRANSCRIPTIONal
MM50RIKEN_12120	COG2252	PERMEase
MM50RIKEN_12130	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
MM50RIKEN_12180	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
MM50RIKEN_12190	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
MM50RIKEN_12200	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
MM50RIKEN_12220	COG0604	alcohol dehydrogenase
MM50RIKEN_12230	COG3246	L-lysine catabolic process to acetate
MM50RIKEN_12240	COG1607	acyl-coa hydrolase
MM50RIKEN_12260	COG1193	negative regulation of DNA recombination
MM50RIKEN_12280	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MM50RIKEN_12280	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MM50RIKEN_12300	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MM50RIKEN_12340	COG4224	UPF0291 protein
MM50RIKEN_12350	COG2302	S4 RNA-binding domain
MM50RIKEN_12360	COG1132	(ABC) transporter
MM50RIKEN_12410	COG1269	ATP hydrolysis coupled proton transport
MM50RIKEN_12420	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MM50RIKEN_12450	COG1436	Produces ATP from ADP in the presence of a proton gradient across the membrane
MM50RIKEN_12460	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
MM50RIKEN_12470	COG1156	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
MM50RIKEN_12480	COG1394	ATPase activity, coupled to movement of substances
MM50RIKEN_12610	COG1309	transcriptional regulator
MM50RIKEN_12630	COG0740	serine-type endopeptidase activity
MM50RIKEN_12650	COG0456	acetyltransferase
MM50RIKEN_12890	COG1484	DNA-dependent DNA replication
MM50RIKEN_12940	COG1191	sigma factor activity
MM50RIKEN_12950	COG2226	methyltransferase
MM50RIKEN_12990	COG4566	intracellular signal transduction
MM50RIKEN_13000	COG1760	l-serine dehydratase
MM50RIKEN_13010	COG1760	l-serine dehydratase
MM50RIKEN_13020	COG2011	ABC-type metal ion transport system permease component
MM50RIKEN_13030	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MM50RIKEN_13040	COG1464	Belongs to the NlpA lipoprotein family
MM50RIKEN_13070	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MM50RIKEN_13080	COG0358	DNA primase activity
MM50RIKEN_13110	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
MM50RIKEN_13140	COG4492	Belongs to the UPF0735 family
MM50RIKEN_13150	COG0745	RESPONSE REGULATOR receiver
MM50RIKEN_13170	COG0750	zinc metalloprotease
MM50RIKEN_13200	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MM50RIKEN_13210	COG0765	amino acid transport
MM50RIKEN_13220	COG1126	abc transporter atp-binding protein
MM50RIKEN_13250	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
MM50RIKEN_13260	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MM50RIKEN_13300	COG0464	growth
MM50RIKEN_13310	COG1217	gtp-binding protein TYPA
MM50RIKEN_13360	COG2801	Transposase and inactivated derivatives
MM50RIKEN_13440	COG1598	PFAM Uncharacterised protein family UPF0150
MM50RIKEN_13520	COG2217	Heavy metal translocating P-type atpase
MM50RIKEN_13530	COG0534	Mate efflux family protein
MM50RIKEN_13570	COG0629	single-stranded DNA binding
MM50RIKEN_13590	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MM50RIKEN_13600	COG0758	DNA mediated transformation
MM50RIKEN_13610	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MM50RIKEN_13620	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
MM50RIKEN_13630	COG0416	fatty acid biosynthetic process
MM50RIKEN_13650	COG0571	ribonuclease III activity
MM50RIKEN_13660	COG0546	phosphoglycolate phosphatase activity
MM50RIKEN_13670	COG0582	viral genome integration into host DNA
MM50RIKEN_13690	COG2337	Toxic component of a toxin-antitoxin (TA) module
MM50RIKEN_13780	COG1959	2 iron, 2 sulfur cluster binding
MM50RIKEN_13790	COG4974	Belongs to the 'phage' integrase family
MM50RIKEN_13940	COG0270	DNA (cytosine-5-)-methyltransferase activity
MM50RIKEN_14070	COG1475	DNA binding
MM50RIKEN_14150	COG0714	Associated with various cellular activities
MM50RIKEN_14190	COG0534	Mate efflux family protein
MM50RIKEN_14210	COG4869	propanediol catabolic process
MM50RIKEN_14230	COG0583	DNA-binding transcription factor activity
MM50RIKEN_14240	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MM50RIKEN_14250	COG0519	Catalyzes the synthesis of GMP from XMP
MM50RIKEN_14260	COG4974	Belongs to the 'phage' integrase family
MM50RIKEN_14300	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
MM50RIKEN_14350	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MM50RIKEN_14450	COG0745	RESPONSE REGULATOR receiver
MM50RIKEN_14460	COG2738	Putative neutral zinc metallopeptidase
MM50RIKEN_14510	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MM50RIKEN_14520	COG0628	permease
MM50RIKEN_14550	COG1132	(ABC) transporter
MM50RIKEN_14590	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MM50RIKEN_14610	COG4589	Belongs to the CDS family
MM50RIKEN_14620	COG0204	Acyl-transferase
MM50RIKEN_14680	COG4716	Myosin-crossreactive antigen
MM50RIKEN_14700	COG0745	RESPONSE REGULATOR receiver
MM50RIKEN_14710	COG3850	Histidine kinase
MM50RIKEN_14710	COG5002	protein histidine kinase activity
MM50RIKEN_14720	COG1028	Short-chain dehydrogenase reductase Sdr
MM50RIKEN_14910	COG0629	single-stranded DNA binding
MM50RIKEN_15150	COG4496	protein, YerC YecD
MM50RIKEN_15160	COG2226	methyltransferase
MM50RIKEN_15170	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
MM50RIKEN_15240	COG0747	negative chemotaxis
MM50RIKEN_15250	COG4608	Belongs to the ABC transporter superfamily
MM50RIKEN_15270	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MM50RIKEN_15280	COG1132	(ABC) transporter
MM50RIKEN_15300	COG2207	Transcriptional regulator
MM50RIKEN_15300	COG3708	Transcriptional regulator
MM50RIKEN_15340	COG1309	transcriptional regulator
MM50RIKEN_15350	COG2226	methyltransferase
MM50RIKEN_15370	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
MM50RIKEN_15400	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MM50RIKEN_15490	COG1132	(ABC) transporter
MM50RIKEN_15500	COG1132	(ABC) transporter
MM50RIKEN_15550	COG1528	Iron-storage protein
MM50RIKEN_15570	COG1054	Belongs to the UPF0176 family
MM50RIKEN_15600	COG0492	ferredoxin-NADP+ reductase activity
MM50RIKEN_15610	COG0426	domain, Protein
MM50RIKEN_15630	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MM50RIKEN_15640	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MM50RIKEN_15650	COG0426	domain, Protein
MM50RIKEN_15660	COG1960	acyl-CoA dehydrogenase activity
MM50RIKEN_15680	COG2357	RelA SpoT domain protein
MM50RIKEN_15690	COG0446	pyridine nucleotide-disulphide oxidoreductase
MM50RIKEN_15740	COG1773	rubredoxin
MM50RIKEN_15760	COG2033	superoxide reductase activity
MM50RIKEN_15770	COG1592	Rubrerythrin
MM50RIKEN_15790	COG1342	Belongs to the UPF0251 family
MM50RIKEN_15810	COG1396	sequence-specific DNA binding
MM50RIKEN_16030	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MM50RIKEN_16060	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MM50RIKEN_16070	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MM50RIKEN_16070	COG2198	Histidine kinase
MM50RIKEN_16070	COG2205	protein histidine kinase activity
MM50RIKEN_16070	COG0784	Response regulator, receiver
MM50RIKEN_16100	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
MM50RIKEN_16140	COG0784	Response regulator, receiver
MM50RIKEN_16140	COG2205	protein histidine kinase activity
MM50RIKEN_16160	COG1966	Carbon starvation protein
MM50RIKEN_16200	COG0674	pyruvate-flavodoxin oxidoreductase activity
MM50RIKEN_16200	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
MM50RIKEN_16200	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
MM50RIKEN_16200	COG1013	pyruvate-flavodoxin oxidoreductase activity
MM50RIKEN_16210	COG0129	dihydroxy-acid dehydratase activity
MM50RIKEN_16220	COG1414	Transcriptional regulator
MM50RIKEN_16240	COG1028	Short-chain dehydrogenase reductase Sdr
MM50RIKEN_16250	COG2610	gluconate transmembrane transporter activity
MM50RIKEN_16260	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MM50RIKEN_16270	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MM50RIKEN_16280	COG0049	tRNA binding
MM50RIKEN_16290	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MM50RIKEN_16310	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
MM50RIKEN_16340	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MM50RIKEN_16340	COG1522	sequence-specific DNA binding
MM50RIKEN_16350	COG0017	Asparaginyl-tRNA synthetase
MM50RIKEN_16380	COG2964	Protein conserved in bacteria
MM50RIKEN_16390	COG3118	belongs to the thioredoxin family
MM50RIKEN_16440	COG0372	Belongs to the citrate synthase family
MM50RIKEN_16450	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
MM50RIKEN_16460	COG0538	isocitrate dehydrogenase activity
MM50RIKEN_16480	COG2252	PERMEase
MM50RIKEN_16500	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
MM50RIKEN_16550	COG0683	leucine binding
MM50RIKEN_16700	COG2309	aminopeptidase activity
MM50RIKEN_16710	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MM50RIKEN_16740	COG1674	ftsk spoiiie
MM50RIKEN_16750	COG1968	undecaprenyl-diphosphatase activity
MM50RIKEN_16760	COG2002	toxin-antitoxin pair type II binding
MM50RIKEN_16770	COG2715	membrane protein required for spore maturation
MM50RIKEN_16780	COG0700	Nucleoside recognition
MM50RIKEN_16800	COG5002	protein histidine kinase activity
MM50RIKEN_16810	COG0745	RESPONSE REGULATOR receiver
MM50RIKEN_16830	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
MM50RIKEN_16840	COG0581	inorganic phosphate transmembrane transporter activity
MM50RIKEN_16850	COG0573	inorganic phosphate transmembrane transporter activity
MM50RIKEN_16860	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
MM50RIKEN_16880	COG0583	DNA-binding transcription factor activity
MM50RIKEN_16910	COG3409	Peptidoglycan-binding domain 1 protein
MM50RIKEN_16910	COG0860	N-Acetylmuramoyl-L-alanine amidase
MM50RIKEN_16930	COG1187	pseudouridine synthase activity
MM50RIKEN_16940	COG3835	regulator
MM50RIKEN_16980	COG2239	Acts as a magnesium transporter
MM50RIKEN_16990	COG3845	ABC transporter
MM50RIKEN_17000	COG4603	Belongs to the binding-protein-dependent transport system permease family
MM50RIKEN_17010	COG1079	Belongs to the binding-protein-dependent transport system permease family
MM50RIKEN_17110	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MM50RIKEN_17130	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MM50RIKEN_17140	COG1381	Involved in DNA repair and RecF pathway recombination
MM50RIKEN_17150	COG1193	negative regulation of DNA recombination
MM50RIKEN_17190	COG0210	DNA helicase
MM50RIKEN_17200	COG2189	Belongs to the N(4) N(6)-methyltransferase family
MM50RIKEN_17230	COG0582	viral genome integration into host DNA
MM50RIKEN_17310	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
MM50RIKEN_17330	COG0534	Mate efflux family protein
MM50RIKEN_17380	COG2239	Acts as a magnesium transporter
MM50RIKEN_17390	COG1132	(ABC) transporter
MM50RIKEN_17420	COG1595	DNA-templated transcription, initiation
MM50RIKEN_17430	COG2755	lipolytic protein G-D-S-L family
MM50RIKEN_17450	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
MM50RIKEN_17460	COG0543	2 iron, 2 sulfur cluster binding
MM50RIKEN_17470	COG0167	dihydroorotate dehydrogenase activity
MM50RIKEN_17480	COG0284	orotidine-5'-phosphate decarboxylase activity
MM50RIKEN_17500	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MM50RIKEN_17510	COG0540	Belongs to the ATCase OTCase family
MM50RIKEN_17530	COG1924	4 iron, 4 sulfur cluster binding
MM50RIKEN_17540	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
MM50RIKEN_17550	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
MM50RIKEN_17570	COG0601	transmembrane transport
MM50RIKEN_17580	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MM50RIKEN_17590	COG0444	Belongs to the ABC transporter superfamily
MM50RIKEN_17600	COG4608	Belongs to the ABC transporter superfamily
MM50RIKEN_17620	COG1757	Na H antiporter
MM50RIKEN_17630	COG0745	RESPONSE REGULATOR receiver
MM50RIKEN_17660	COG2385	sporulation resulting in formation of a cellular spore
MM50RIKEN_17670	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MM50RIKEN_17690	COG3842	ATPase activity
MM50RIKEN_17700	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MM50RIKEN_17710	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MM50RIKEN_17740	COG0622	Phosphoesterase
MM50RIKEN_17750	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
MM50RIKEN_17770	COG1032	radical SAM domain protein
MM50RIKEN_17780	COG0406	alpha-ribazole phosphatase activity
MM50RIKEN_17820	COG0071	Belongs to the small heat shock protein (HSP20) family
MM50RIKEN_17830	COG0745	RESPONSE REGULATOR receiver
MM50RIKEN_17840	COG3850	Histidine kinase
MM50RIKEN_17840	COG5002	protein histidine kinase activity
MM50RIKEN_17850	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MM50RIKEN_17890	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MM50RIKEN_17900	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
MM50RIKEN_17910	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
MM50RIKEN_17920	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
MM50RIKEN_17930	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
MM50RIKEN_17940	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
MM50RIKEN_17970	COG0572	uridine kinase
MM50RIKEN_18010	COG2059	Chromate
MM50RIKEN_18020	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
MM50RIKEN_18020	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
MM50RIKEN_18070	COG1573	uracil-dna glycosylase
MM50RIKEN_18100	COG1132	(ABC) transporter
MM50RIKEN_18110	COG1132	(ABC) transporter
MM50RIKEN_18120	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MM50RIKEN_18140	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
MM50RIKEN_18150	COG1459	type II secretion system
MM50RIKEN_18170	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
MM50RIKEN_18250	COG2801	Transposase and inactivated derivatives
MM50RIKEN_18310	COG0653	protein targeting
MM50RIKEN_18320	COG1496	oxidoreductase activity
MM50RIKEN_18340	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MM50RIKEN_18360	COG0726	polysaccharide deacetylase
MM50RIKEN_18390	COG0202	RNA polymerase activity
MM50RIKEN_18400	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MM50RIKEN_18410	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MM50RIKEN_18420	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MM50RIKEN_18430	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MM50RIKEN_18450	COG0024	Methionine aminopeptidase
MM50RIKEN_18460	COG0563	adenylate kinase activity
MM50RIKEN_18480	COG0200	Binds to the 23S rRNA
MM50RIKEN_18490	COG1841	ribosomal large subunit assembly
MM50RIKEN_18500	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MM50RIKEN_18510	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MM50RIKEN_18520	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MM50RIKEN_18530	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MM50RIKEN_18540	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MM50RIKEN_18550	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MM50RIKEN_18560	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MM50RIKEN_18570	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MM50RIKEN_18580	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MM50RIKEN_18590	COG0255	Belongs to the universal ribosomal protein uL29 family
MM50RIKEN_18600	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MM50RIKEN_18630	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MM50RIKEN_18640	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MM50RIKEN_18650	COG0089	rRNA binding
MM50RIKEN_18660	COG0088	Forms part of the polypeptide exit tunnel
MM50RIKEN_18670	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MM50RIKEN_18680	COG0051	transcription antitermination factor activity, RNA binding
MM50RIKEN_18710	COG0583	DNA-binding transcription factor activity
MM50RIKEN_18740	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
MM50RIKEN_18760	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MM50RIKEN_18780	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MM50RIKEN_18790	COG0598	Magnesium transport protein CorA
MM50RIKEN_18800	COG0481	GTPase activity
MM50RIKEN_18810	COG0481	GTPase activity
MM50RIKEN_18820	COG0481	GTPase activity
MM50RIKEN_18830	COG0481	GTPase activity
MM50RIKEN_18840	COG0481	GTPase activity
MM50RIKEN_18860	COG4463	regulation of RNA biosynthetic process
MM50RIKEN_18880	COG0542	response to heat
MM50RIKEN_18910	COG4120	Belongs to the binding-protein-dependent transport system permease family
MM50RIKEN_18920	COG1122	ATPase activity
MM50RIKEN_18930	COG0564	pseudouridine synthase activity
MM50RIKEN_18940	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MM50RIKEN_18960	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MM50RIKEN_18970	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
MM50RIKEN_18990	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MM50RIKEN_19000	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MM50RIKEN_19030	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
MM50RIKEN_19040	COG1799	cell septum assembly
MM50RIKEN_19080	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
MM50RIKEN_19100	COG1757	Na H antiporter
MM50RIKEN_19110	COG4948	Mandelate Racemase Muconate Lactonizing
MM50RIKEN_19120	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
MM50RIKEN_19130	COG0148	phosphopyruvate hydratase activity
MM50RIKEN_19150	COG3829	transcription factor binding
MM50RIKEN_19160	COG2732	(Barnase) inhibitor
MM50RIKEN_19180	COG1686	Belongs to the peptidase S11 family
MM50RIKEN_19190	COG0166	Belongs to the GPI family
MM50RIKEN_19280	COG0445	tRNA wobble uridine modification
MM50RIKEN_19350	COG0446	pyridine nucleotide-disulphide oxidoreductase
MM50RIKEN_19370	COG2205	protein histidine kinase activity
MM50RIKEN_19380	COG0745	RESPONSE REGULATOR receiver
MM50RIKEN_19390	COG1757	Na H antiporter
MM50RIKEN_19400	COG1757	Na H antiporter
MM50RIKEN_19430	COG3275	phosphorelay sensor kinase activity
MM50RIKEN_19440	COG0251	oxidation-reduction process
MM50RIKEN_19510	COG2337	Toxic component of a toxin-antitoxin (TA) module
MM50RIKEN_19670	COG3906	Belongs to the UPF0473 family
MM50RIKEN_19680	COG0501	Belongs to the peptidase M48B family
MM50RIKEN_19690	COG3843	relaxase mobilization nuclease domain protein
MM50RIKEN_19770	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MM50RIKEN_19770	COG0551	DNA topoisomerase type I activity
MM50RIKEN_19800	COG0358	DNA primase activity
MM50RIKEN_19910	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MM50RIKEN_19910	COG0551	DNA topoisomerase type I activity
MM50RIKEN_19920	COG1373	ATPase (AAA superfamily
MM50RIKEN_19950	COG0741	lytic transglycosylase activity
MM50RIKEN_19950	COG0791	NLP P60 protein
MM50RIKEN_20190	COG1475	DNA binding
MM50RIKEN_20200	COG1192	Involved in chromosome partitioning
MM50RIKEN_20360	COG0791	NLP P60 protein
MM50RIKEN_20360	COG0741	lytic transglycosylase activity
MM50RIKEN_20390	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MM50RIKEN_20390	COG0551	DNA topoisomerase type I activity
MM50RIKEN_20440	COG3843	relaxase mobilization nuclease domain protein
MM50RIKEN_20460	COG2207	Transcriptional regulator
MM50RIKEN_20460	COG1609	Transcriptional regulator
MM50RIKEN_20490	COG1129	ABC transporter
MM50RIKEN_20500	COG2375	cellular response to nickel ion
MM50RIKEN_20500	COG1132	(ABC) transporter
MM50RIKEN_20510	COG1132	(ABC) transporter
MM50RIKEN_20580	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MM50RIKEN_20620	COG0305	Participates in initiation and elongation during chromosome replication
MM50RIKEN_20640	COG0359	binds to the 23S rRNA
MM50RIKEN_20650	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
MM50RIKEN_20660	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MM50RIKEN_20710	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
MM50RIKEN_20720	COG1733	regulation of RNA biosynthetic process
MM50RIKEN_20730	COG1279	arginine transmembrane transporter activity
MM50RIKEN_20740	COG2031	fatty acid transporter
MM50RIKEN_20750	COG1028	Short-chain dehydrogenase reductase Sdr
MM50RIKEN_20790	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
MM50RIKEN_20800	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
MM50RIKEN_20810	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MM50RIKEN_20880	COG1077	Cell shape determining protein MreB Mrl
MM50RIKEN_20890	COG1040	competence protein
MM50RIKEN_20900	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
MM50RIKEN_20940	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MM50RIKEN_20970	COG0556	nucleotide-excision repair
MM50RIKEN_20980	COG2003	Belongs to the UPF0758 family
MM50RIKEN_21000	COG0813	purine-nucleoside phosphorylase activity
MM50RIKEN_21020	COG0012	GTP binding
MM50RIKEN_21030	COG0582	viral genome integration into host DNA
MM50RIKEN_21050	COG1484	DNA-dependent DNA replication
MM50RIKEN_21140	COG1373	ATPase (AAA superfamily
MM50RIKEN_21170	COG0628	permease
MM50RIKEN_21180	COG0569	domain protein
MM50RIKEN_21190	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
MM50RIKEN_21200	COG4536	flavin adenine dinucleotide binding
MM50RIKEN_21210	COG2205	protein histidine kinase activity
MM50RIKEN_21220	COG0745	RESPONSE REGULATOR receiver
MM50RIKEN_21240	COG1120	ATPase activity
MM50RIKEN_21250	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MM50RIKEN_21350	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MM50RIKEN_21360	COG0085	RNA polymerase activity
MM50RIKEN_21370	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MM50RIKEN_21370	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MM50RIKEN_21380	COG0708	Exodeoxyribonuclease III
MM50RIKEN_21440	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MM50RIKEN_21460	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
MM50RIKEN_21480	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MM50RIKEN_21490	COG0149	triose-phosphate isomerase activity
MM50RIKEN_21540	COG2957	Belongs to the agmatine deiminase family
MM50RIKEN_21550	COG0531	amino acid
MM50RIKEN_21560	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MM50RIKEN_21590	COG1461	Dihydroxyacetone kinase
MM50RIKEN_21640	COG3681	Belongs to the UPF0597 family
MM50RIKEN_21690	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
MM50RIKEN_21710	COG2264	protein methyltransferase activity
MM50RIKEN_21720	COG2720	vancomycin resistance protein
MM50RIKEN_21730	COG1475	DNA binding
MM50RIKEN_21760	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
MM50RIKEN_21770	COG0826	peptidase U32
MM50RIKEN_21790	COG0756	dUTP diphosphatase activity
MM50RIKEN_21800	COG0424	maF-like protein
MM50RIKEN_21830	COG0768	penicillin binding
MM50RIKEN_21850	COG1192	Involved in chromosome partitioning
MM50RIKEN_21860	COG1475	DNA binding
MM50RIKEN_21870	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MM50RIKEN_21880	COG1970	mechanosensitive ion channel activity
MM50RIKEN_21890	COG0357	Ribosomal RNA small subunit methyltransferase G
MM50RIKEN_21900	COG2894	cell division
MM50RIKEN_21910	COG1803	Methylglyoxal synthase
MM50RIKEN_21930	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
MM50RIKEN_21960	COG0534	Mate efflux family protein
MM50RIKEN_21970	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
MM50RIKEN_21970	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MM50RIKEN_21990	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
MM50RIKEN_22000	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MM50RIKEN_22010	COG0328	RNA-DNA hybrid ribonuclease activity
MM50RIKEN_22020	COG1720	tRNA m6t6A37 methyltransferase activity
MM50RIKEN_22040	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MM50RIKEN_22050	COG0187	DNA topoisomerase II activity
MM50RIKEN_22090	COG0592	DNA-directed DNA polymerase activity
MM50RIKEN_22120	COG0594	ribonuclease P activity
MM50RIKEN_22130	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
MM50RIKEN_22140	COG0706	membrane insertase activity
MM50RIKEN_22160	COG1847	R3H domain protein
MM50RIKEN_22170	COG1185	polyribonucleotide nucleotidyltransferase activity
MM50RIKEN_22180	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MM50RIKEN_22200	COG1725	Transcriptional regulator
MM50RIKEN_22210	COG1131	(ABC) transporter
MM50RIKEN_22240	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
MM50RIKEN_22240	COG1013	pyruvate-flavodoxin oxidoreductase activity
MM50RIKEN_22240	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
MM50RIKEN_22240	COG0674	pyruvate-flavodoxin oxidoreductase activity
MM50RIKEN_22250	COG0606	chelatase, subunit chli
MM50RIKEN_22260	COG0301	tRNA thio-modification
MM50RIKEN_22270	COG1546	Belongs to the CinA family
MM50RIKEN_22270	COG1058	Belongs to the CinA family
MM50RIKEN_22290	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MM50RIKEN_22340	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
MM50RIKEN_22360	COG0739	heme binding
MM50RIKEN_22370	COG2177	Part of the ABC transporter FtsEX involved in
MM50RIKEN_22380	COG2884	Cell division ATP-binding protein ftsE
MM50RIKEN_22420	COG3246	L-lysine catabolic process to acetate
MM50RIKEN_22430	COG1250	3-hydroxyacyl-CoA dehydrogenase
MM50RIKEN_22450	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
MM50RIKEN_22470	COG0183	Belongs to the thiolase family
MM50RIKEN_22480	COG1132	(ABC) transporter
MM50RIKEN_22490	COG1132	(ABC) transporter
MM50RIKEN_22500	COG0523	cobalamin synthesis protein
MM50RIKEN_22590	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
MM50RIKEN_22600	COG2002	toxin-antitoxin pair type II binding
MM50RIKEN_22660	COG1733	regulation of RNA biosynthetic process
MM50RIKEN_22680	COG0582	viral genome integration into host DNA
MM50RIKEN_22690	COG0733	neurotransmitter:sodium symporter activity
MM50RIKEN_22730	COG2050	protein possibly involved in aromatic compounds catabolism
MM50RIKEN_22750	COG0444	Belongs to the ABC transporter superfamily
MM50RIKEN_22770	COG0601	transmembrane transport
MM50RIKEN_22800	COG0628	permease
MM50RIKEN_22810	COG1597	lipid kinase activity
MM50RIKEN_22820	COG0193	aminoacyl-tRNA hydrolase activity
MM50RIKEN_22830	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MM50RIKEN_22850	COG0183	Belongs to the thiolase family
MM50RIKEN_22870	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
MM50RIKEN_22890	COG0018	arginyl-trna synthetase
MM50RIKEN_22900	COG2195	Cleaves the N-terminal amino acid of tripeptides
MM50RIKEN_22930	COG1420	regulation of RNA biosynthetic process
MM50RIKEN_22960	COG0443	Heat shock 70 kDa protein
MM50RIKEN_22970	COG0484	heat shock protein binding
MM50RIKEN_22990	COG0698	ribose 5-phosphate isomerase
MM50RIKEN_23010	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MM50RIKEN_23020	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
MM50RIKEN_23030	COG1609	Transcriptional regulator
MM50RIKEN_23050	COG2183	response to ionizing radiation
MM50RIKEN_23060	COG4868	Belongs to the UPF0371 family
MM50RIKEN_23090	COG0745	RESPONSE REGULATOR receiver
MM50RIKEN_23100	COG5002	protein histidine kinase activity
MM50RIKEN_23110	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
MM50RIKEN_23130	COG1388	LysM domain
MM50RIKEN_23130	COG1134	teichoic acid transport
MM50RIKEN_23160	COG0635	Involved in the biosynthesis of porphyrin-containing compound
MM50RIKEN_23200	COG1194	a g-specific adenine glycosylase
MM50RIKEN_23240	COG0187	DNA topoisomerase II activity
MM50RIKEN_23250	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MM50RIKEN_23260	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MM50RIKEN_23280	COG0673	inositol 2-dehydrogenase activity
MM50RIKEN_23290	COG1940	carbohydrate kinase activity
MM50RIKEN_23300	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MM50RIKEN_23320	COG1802	Transcriptional regulator
MM50RIKEN_23330	COG1116	anion transmembrane transporter activity
MM50RIKEN_23340	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MM50RIKEN_23350	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MM50RIKEN_23360	COG2878	Part of a membrane complex involved in electron transport
MM50RIKEN_23360	COG1245	4Fe-4S binding domain
MM50RIKEN_23370	COG4657	Part of a membrane complex involved in electron transport
MM50RIKEN_23380	COG4660	Part of a membrane complex involved in electron transport
MM50RIKEN_23390	COG4658	electron transport chain
MM50RIKEN_23400	COG4656	Part of a membrane complex involved in electron transport
MM50RIKEN_23440	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
MM50RIKEN_23470	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MM50RIKEN_23490	COG0095	Lipoate-protein ligase
MM50RIKEN_23500	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MM50RIKEN_23510	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MM50RIKEN_23520	COG0509	glycine decarboxylation via glycine cleavage system
MM50RIKEN_23530	COG0404	The glycine cleavage system catalyzes the degradation of glycine
MM50RIKEN_23600	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MM50RIKEN_23640	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MM50RIKEN_23640	COG0574	Belongs to the PEP-utilizing enzyme family
MM50RIKEN_23660	COG1774	PSP1 C-terminal conserved region
MM50RIKEN_23690	COG0084	hydrolase, TatD family'
MM50RIKEN_23710	COG1131	(ABC) transporter
MM50RIKEN_23810	COG1518	maintenance of DNA repeat elements
MM50RIKEN_23960	COG0582	viral genome integration into host DNA
MM50RIKEN_23970	COG2207	Transcriptional regulator
MM50RIKEN_24010	COG1175	transmembrane transport
MM50RIKEN_24030	COG0569	domain protein
MM50RIKEN_24040	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
MM50RIKEN_24050	COG0534	Mate efflux family protein
MM50RIKEN_24060	COG1522	sequence-specific DNA binding
MM50RIKEN_24080	COG0482	sulfurtransferase activity
MM50RIKEN_24090	COG2205	protein histidine kinase activity
MM50RIKEN_24160	COG3457	Alanine racemase
MM50RIKEN_24230	COG4974	Belongs to the 'phage' integrase family
MM50RIKEN_24290	COG0456	acetyltransferase
MM50RIKEN_24310	COG0281	malic enzyme
MM50RIKEN_24340	COG3938	Belongs to the proline racemase family
MM50RIKEN_24350	COG3829	transcription factor binding
MM50RIKEN_24360	COG1757	Na H antiporter
MM50RIKEN_24370	COG0165	Argininosuccinate lyase
MM50RIKEN_24400	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
MM50RIKEN_24410	COG1760	l-serine dehydratase
MM50RIKEN_24420	COG1757	Na H antiporter
MM50RIKEN_24430	COG0686	Belongs to the AlaDH PNT family