locus-tag	class	description
D1115_00005	ENOG4105QTB	Flavodoxin
D1115_00010	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
D1115_00015	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
D1115_00020	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
D1115_00025	ENOG4105NVJ	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
D1115_00040	ENOG4105E5Q	amino acid AbC transporter
D1115_00045	ENOG4105EAB	amino acid AbC transporter
D1115_00055	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
D1115_00060	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
D1115_00070	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
D1115_00080	ENOG4108ZNX	Heat shock protein
D1115_00085	ENOG4105JKW	Valine--pyruvate aminotransferase
D1115_00090	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
D1115_00095	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
D1115_00110	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
D1115_00125	ENOG4105D3Z	quinone oxidoreductase, yhdh yhfp family
D1115_00130	ENOG4105CHU	acetyl-coa acetyltransferase
D1115_00135	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
D1115_00145	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
D1115_00150	ENOG4108RR8	protoporphyrinogen oxidase
D1115_00205	ENOG4105WMR	Protein CrcB homolog
D1115_00210	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
D1115_00220	ENOG4105D06	uba thif-type nad fad binding protein
D1115_00225	ENOG4105WHD	thiamine biosynthesis protein ThiS
D1115_00230	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
D1115_00235	ENOG4105D41	biosynthesis protein thiH
D1115_00240	ENOG4105DC7	peptidase M24
D1115_00240	ENOG4105DC7	peptidase M24
D1115_00245	ENOG4105G2Y	Transcriptional regulator
D1115_00250	ENOG4105CNH	Multidrug resistance protein MdtL
D1115_00270	ENOG4105E18	UPF0276 protein
D1115_00280	ENOG4105C4R	Atp-dependent dna helicase
D1115_00290	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
D1115_00305	ENOG4105FR1	rard protein
D1115_00310	ENOG4105C9U	ATP-dependent DNA helicase RecQ
D1115_00325	ENOG4105EX9	Membrane
D1115_00330	ENOG4105C9X	ppx gppa phosphatase
D1115_00335	ENOG4105C1J	atp-dependent rna helicase
D1115_00340	ENOG4105K63	Thioredoxin
D1115_00345	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
D1115_00355	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
D1115_00360	ENOG4108ZIT	Ferredoxin, 2FE-2S
D1115_00365	ENOG4107QK7	reductase
D1115_00420	ENOG41076E6	Uroporphyrinogen-III Synthase
D1115_00425	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
D1115_00435	ENOG4105XQ6	frataxin-like protein
D1115_00445	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
D1115_00450	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
D1115_00465	ENOG4105DFC	had-superfamily hydrolase, subfamily ia, variant
D1115_00470	ENOG4106IUH	DTW domain containing protein
D1115_00485	ENOG4105DQF	Hydrolase
D1115_00490	ENOG4108EUD	Lysophospholipase
D1115_00495	ENOG410829K	Lysine exporter protein (Lyse ygga)
D1115_00500	ENOG41082YX	Transcriptional regulator, arsr family
D1115_00505	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
D1115_00560	ENOG4106H78	methyltransferase
D1115_00570	ENOG4105CAK	Cell division ATP-binding protein ftsE
D1115_00575	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
D1115_00580	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
D1115_00585	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
D1115_00590	ENOG4105EBW	Rhomboid-type serine protease that catalyzes intramembrane proteolysis (By similarity)
D1115_00595	ENOG4105X6C	Flagellar basal body-associated protein FliL
D1115_00600	ENOG4105VEI	Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway (By similarity)
D1115_00605	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
D1115_00610	ENOG4105E55	glycerol-3-phosphate acyltransferase
D1115_00620	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
D1115_00630	ENOG4107R73	Mate efflux family protein
D1115_00635	ENOG4105DX1	Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation (By similarity)
D1115_00650	ENOG4107R9T	Catalyzes the formation of 5-methyl-uridine at position 54 (m5U54) in all tRNAs (By similarity)
D1115_00655	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
D1115_00665	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
D1115_00715	ENOG4105D4A	Cell wall formation (By similarity)
D1115_00720	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
D1115_00765	ENOG4105PM1	preprotein translocase subunit SecE
D1115_00770	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
D1115_00775	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
D1115_00780	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
D1115_00785	ENOG4108VZM	50s ribosomal protein L10
D1115_00790	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
D1115_00795	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
D1115_00800	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
D1115_00805	ENOG4108ZVW	Anti-RNA polymerase sigma 70 factor
D1115_00810	ENOG4105E09	nadh pyrophosphatase
D1115_00815	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
D1115_00820	ENOG4108RG0	uracil-dna glycosylase
D1115_00825	ENOG4105JPG	D-isomer specific 2-hydroxyacid dehydrogenase
D1115_00830	ENOG4105R2J	Conserved Protein
D1115_00850	ENOG4105C12	Phosphoribosylglycinamide synthetase
D1115_00855	ENOG4105DC1	bifunctional purine biosynthesis protein purh
D1115_00870	ENOG4108M3R	transcriptional activator CadC
D1115_00880	ENOG4105D5Q	Arginine ornithine antiporter
D1115_00885	ENOG4105CXN	decarboxylase
D1115_00960	ENOG4105BZU	Histidine kinase
D1115_00965	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
D1115_00970	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
D1115_00975	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
D1115_00980	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
D1115_00985	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
D1115_00990	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
D1115_00995	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
D1115_01010	ENOG4105D8G	Major Facilitator superfamily
D1115_01015	ENOG4105BZU	Histidine kinase
D1115_01025	ENOG4107QN1	sodium solute
D1115_01035	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
D1115_01045	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
D1115_01050	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
D1115_01055	ENOG4108IJ0	Aspartate ammonia-lyase
D1115_01060	ENOG4108YH1	overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7
D1115_01065	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
D1115_01070	ENOG4105E0F	Histidine kinase
D1115_01075	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
D1115_01080	ENOG4108SPG	Periplasmic Protein
D1115_01085	ENOG41076HS	cation diffusion facilitator family transporter
D1115_01090	ENOG4105CTQ	phosphohexokinase
D1115_01095	ENOG4107QI1	Mate efflux family protein
D1115_01105	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
D1115_01110	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
D1115_01125	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
D1115_01130	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
D1115_01135	ENOG4108VP9	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity)
D1115_01140	ENOG4108WJH	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity)
D1115_01155	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
D1115_01165	ENOG41062JF	Transcriptional regulator
D1115_01175	ENOG41063SB	peptidase
D1115_01180	ENOG4105D7W	serine acetyltransferase
D1115_01185	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
D1115_01190	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
D1115_01195	ENOG4107YZP	Rhodanese domain protein
D1115_01200	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
D1115_01210	ENOG4105C8Q	Methyl-accepting chemotaxis
D1115_01215	ENOG4105C8P	)-transporter
D1115_01225	ENOG4105DJ4	phosphatidylserine decarboxylase
D1115_01230	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
D1115_01235	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
D1115_01315	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
D1115_01320	ENOG4105K8N	protein family UPF0079, ATPase
D1115_01325	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
D1115_01335	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
D1115_01340	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
D1115_01345	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
D1115_01350	ENOG4107QJR	hflk protein
D1115_01355	ENOG4105EPW	hflc protein
D1115_01365	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
D1115_01370	ENOG4108UV7	flagellar protein motX
D1115_01375	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
D1115_01380	ENOG4105KPV	Transcriptional regulator
D1115_01385	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
D1115_01390	ENOG4105C2N	RNA methyltransferase TrmH family group 3
D1115_01395	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
D1115_01400	ENOG4105C31	Tryptophanyl-tRNA synthetase
D1115_01405	ENOG4105DDQ	anthranilate synthase
D1115_01410	ENOG4105C8Y	Acetylornithine aminotransferase
D1115_01420	ENOG4105C26	Dehydrogenase
D1115_01430	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
D1115_01435	ENOG4105CJE	phosphoribulokinase (EC 2.7.1.19)
D1115_01440	ENOG4105YP7	UPF0270 protein
D1115_01445	ENOG4105DNZ	Alpha Beta Hydrolase
D1115_01455	ENOG4105C5H	ABC transporter
D1115_01460	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
D1115_01475	ENOG4108YZY	peptidylprolyl cis-trans isomerase
D1115_01485	ENOG4105D44	asparaginase
D1115_01490	ENOG41069P5	Protein slyX homolog
D1115_01500	ENOG4108V1T	peptidylprolyl cis-trans isomerase
D1115_01505	ENOG4105WWK	YheO domain protein
D1115_01510	ENOG4108ZAT	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE (By similarity)
D1115_01515	ENOG4108ZKU	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (By similarity)
D1115_01525	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
D1115_01530	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
D1115_01545	ENOG4105W53	bacterioferritin-associated ferredoxin
D1115_01550	ENOG4108UQY	Iron-storage protein
D1115_01555	ENOG4105C6K	Malic enzyme
D1115_01560	ENOG4105GGQ	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis (By similarity)
D1115_01565	ENOG4105C28	cystathionine
D1115_01570	ENOG4105CFH	Aspartokinase
D1115_01575	ENOG4105SYT	Methylenetetrahydrofolate reductase
D1115_01585	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
D1115_01590	ENOG4105CWC	Acetylornithine deacetylase
D1115_01595	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
D1115_01600	ENOG4105CAS	nag kinase
D1115_01610	ENOG4105CH7	arginosuccinase
D1115_01625	ENOG4105EHV	domain protein
D1115_01630	ENOG4105C5Q	Transcriptional regulator
D1115_01635	ENOG4108JQC	penicillin-binding protein 1A
D1115_01660	ENOG4105E4G	Type IV pilus
D1115_01665	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
D1115_01670	ENOG4105D49	3-dehydroquinate synthase
D1115_01680	ENOG4105DFE	Dna adenine methylase
D1115_01685	ENOG4105DJV	ribulose-phosphate 3-epimerase
D1115_01690	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
D1115_01695	ENOG4108VDV	Binds single-stranded DNA at the primosome assembly site (PAS) (By similarity)
D1115_01700	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
D1115_01705	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
D1115_01715	ENOG4105CDU	Replicative dna helicase
D1115_01720	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
D1115_01730	ENOG4108YXI	Secondary thiamine-phosphate synthase enzyme
D1115_01735	ENOG4107QP8	phosphohexose isomerase
D1115_01745	ENOG4105MYN	Zinc uptake regulation protein
D1115_01750	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
D1115_01770	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
D1115_01775	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
D1115_01780	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
D1115_01850	ENOG4105EEQ	Na H antiporter
D1115_01860	ENOG4105CFH	Aspartokinase
D1115_01870	ENOG4105C5R	Aminotransferase
D1115_01880	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
D1115_01890	ENOG41086KC	Transcriptional regulator
D1115_01895	ENOG4108UUM	single-stranded DNA-binding protein
D1115_01900	ENOG41062P1	Diguanylate cyclase phosphodiesterase
D1115_01935	ENOG4107QHF	type ii secretion system protein e
D1115_01950	ENOG4108VAU	general secretion pathway protein G
D1115_02000	ENOG4105DFF	Rod shape-determining protein mreb
D1115_02005	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
D1115_02010	ENOG4105VQ7	Rod shape-determining protein MreD
D1115_02015	ENOG4108Z03	MAF-like protein
D1115_02020	ENOG4105C03	ribonuclease
D1115_02035	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
D1115_02040	ENOG4108IAB	Phoh family
D1115_02045	ENOG4105BZK	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity)
D1115_02050	ENOG4105D3G	Pseudouridine synthase
D1115_02055	ENOG4105C5I	Dehydrogenase
D1115_02060	ENOG4105N42	UPF0307 protein
D1115_02065	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
D1115_02070	ENOG4105CJW	magnesium transporter
D1115_02075	ENOG41080Z8	PHOSPHOCARRIER protein
D1115_02080	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
D1115_02085	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
D1115_02090	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
D1115_02095	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
D1115_02100	ENOG4108IUZ	ABC transporter
D1115_02105	ENOG4105WI0	lipopolysaccharide transport periplasmic protein lptA
D1115_02115	ENOG4105C2X	Arabinose 5-phosphate isomerase
D1115_02125	ENOG4105DHJ	ABC, transporter
D1115_02130	ENOG4105CY3	ABC transporter, permease
D1115_02135	ENOG4107PE3	Mammalian cell entry related domain protein
D1115_02140	ENOG4105E3I	toluene tolerance
D1115_02150	ENOG4105VFK	BolA family
D1115_02155	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
D1115_02160	ENOG4107S7E	1-acyl-sn-glycerol-3-phosphate acyltransferase
D1115_02165	ENOG4105KME	endoribonuclease L-psp
D1115_02170	ENOG4108R9M	Involved in allosteric regulation of aspartate carbamoyltransferase (By similarity)
D1115_02175	ENOG4105CXT	aspartate transcarbamylase
D1115_02185	ENOG4105DBV	ornithine carbamoyltransferase
D1115_02190	ENOG4105CEU	Arginine dihydrolase
D1115_02205	ENOG4108MJ3	acetyltransferase
D1115_02215	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
D1115_02225	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
D1115_02230	ENOG4108M8S	permease YjgP YjgQ family protein
D1115_02250	ENOG4108KU3	Integrase
D1115_02285	ENOG4105CVR	type I restriction-modification system
D1115_02290	ENOG4105EKX	Restriction modification system DNA (Specificity
D1115_02295	ENOG4107R3N	Filamentation induced by cAMP protein fic
D1115_02305	ENOG4105DZR	Type I site-specific deoxyribonuclease
D1115_02325	ENOG4105DGM	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
D1115_02330	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
D1115_02400	ENOG4105C8Q	Methyl-accepting chemotaxis
D1115_02445	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
D1115_02450	ENOG4105CEN	a g-specific adenine glycosylase
D1115_02455	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
D1115_02465	ENOG4105CSV	Glutaminase
D1115_02470	ENOG4105CSA	Coproporphyrinogen iii oxidase
D1115_02475	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
D1115_02485	ENOG4105VZ9	UPF0235 protein
D1115_02490	ENOG4108VIA	integral membrane protein
D1115_02495	ENOG4105II7	pyrroline-5-carboxylate reductase
D1115_02500	ENOG4105DFA	alanine racemase domain protein
D1115_02505	ENOG4105CZX	twitching motility protein
D1115_02510	ENOG4105CZX	twitching motility protein
D1115_02515	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
D1115_02520	ENOG4108UJU	UPF0301 protein
D1115_02525	ENOG4105D7Z	glutathione synthase
D1115_02530	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
D1115_02535	ENOG4105RWS	endonuclease I
D1115_02540	ENOG4105GPY	SprT protein
D1115_02550	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
D1115_02555	ENOG4105CV1	Transketolase (EC 2.2.1.1)
D1115_02560	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
D1115_02565	ENOG4105BZA	Phosphoglycerate kinase
D1115_02570	ENOG4105D2N	Aldolase
D1115_02580	ENOG4105D64	Mechanosensitive ion channel
D1115_02595	ENOG4105CXD	Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity)
D1115_02600	ENOG4105MPN	Membrane
D1115_02605	ENOG4108JQ1	Dehydrogenase
D1115_02610	ENOG4105E66	phosphoriboisomerase A
D1115_02615	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
D1115_02625	ENOG4107YUN	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
D1115_02635	ENOG4105D0A	hydroxylase
D1115_02640	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
D1115_02660	ENOG4105Y75	tpr repeat protein
D1115_02670	ENOG4108IYU	L-aspartate oxidase
D1115_02675	ENOG4105EMN	RNA polymerase sigma factor
D1115_02695	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
D1115_02700	ENOG4105C3F	Signal peptidase i
D1115_02705	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
D1115_02710	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
D1115_02715	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
D1115_02720	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
D1115_02725	ENOG4105KJV	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
D1115_02730	ENOG4105BZU	Histidine kinase
D1115_02745	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
D1115_02750	ENOG4105DXN	mazG family
D1115_02755	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
D1115_02765	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
D1115_02770	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
D1115_02775	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
D1115_02780	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
D1115_02785	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
D1115_02790	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
D1115_02800	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
D1115_02805	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
D1115_02810	ENOG4107TH8	cina domain protein
D1115_02815	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
D1115_02820	ENOG4105Y3E	Modulates RecA activity (By similarity)
D1115_02825	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
D1115_02830	ENOG4105CFH	Aspartokinase
D1115_02835	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
D1115_02930	ENOG4107QSA	Oxaloacetate decarboxylase
D1115_02935	ENOG4105D9Q	decarboxylase (Beta subunit)
D1115_02945	ENOG4105W39	Membrane
D1115_02965	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
D1115_02970	ENOG4108JU6	CBS domain protein
D1115_02975	ENOG4106KVJ	cytochrome C assembly protein
D1115_02980	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
D1115_02985	ENOG4105K5M	30s ribosomal protein S16
D1115_02990	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
D1115_02995	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
D1115_03000	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
D1115_03010	ENOG4105DHA	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity (By similarity)
D1115_03015	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
D1115_03020	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
D1115_03025	ENOG4105D7Q	type ii secretion system
D1115_03030	ENOG4107QHF	type ii secretion system protein e
D1115_03040	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
D1115_03050	ENOG41073TP	transcriptional regulator
D1115_03055	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
D1115_03060	ENOG4107QSN	dihydrolipoamide acetyltransferase
D1115_03065	ENOG4107QN2	dihydrolipoyl dehydrogenase
D1115_03070	ENOG410630P	Transcriptional regulator
D1115_03075	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
D1115_03080	ENOG41077A9	carbonic anhydrase
D1115_03085	ENOG4105CHH	sulfate transporter
D1115_03090	ENOG4105DA5	(ABC) transporter
D1115_03095	ENOG4105E3A	(ABC) transporter
D1115_03100	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
D1115_03105	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
D1115_03110	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
D1115_03115	ENOG4105DJ0	Poly(A) Polymerase
D1115_03120	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
D1115_03125	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
D1115_03130	ENOG4105PW4	Sugar fermentation stimulation protein homolog
D1115_03135	ENOG4105CQ7	ATP-dependent helicase
D1115_03140	ENOG4105BZ4	penicillin-binding protein
D1115_03145	ENOG4105D78	K07001 NTE family protein
D1115_03150	ENOG4107QIJ	Aconitate hydratase 2
D1115_03155	ENOG4105BZW	Glycerate kinase
D1115_03160	ENOG4107QQ0	gntp family
D1115_03165	ENOG4108IXP	Carbohydrate diacid transcriptional activator CdaR
D1115_03170	ENOG4105XTV	UPF0231 protein
D1115_03175	ENOG4108YZA	Nitrogen regulatory protein pii
D1115_03195	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
D1115_03210	ENOG4105E2D	ec 3.2.1.52
D1115_03215	ENOG4105RD7	BadF BadG BcrA BcrD
D1115_03225	ENOG4108JQ7	(ABC) transporter
D1115_03230	ENOG4105C3U	ABC transporter
D1115_03235	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
D1115_03245	ENOG4107QRA	Extracellular solute-binding protein, family 5
D1115_03260	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
D1115_03270	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
D1115_03275	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
D1115_03280	ENOG4105CW7	secretion protein, HlyD family
D1115_03290	ENOG4105DR5	peptidase
D1115_03295	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
D1115_03310	ENOG4107QE9	Inherit from COG: Membrane
D1115_03315	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
D1115_03320	ENOG4105HBR	Rna-binding protein
D1115_03325	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
D1115_03330	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
D1115_03335	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
D1115_03355	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
D1115_03360	ENOG4105CHV	Transcription elongation factor NusA
D1115_03370	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
D1115_03375	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
D1115_03380	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
D1115_03385	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
D1115_03395	ENOG41067TZ	transcriptional regulator, MarR family
D1115_03400	ENOG4105C3S	Mate efflux family protein
D1115_03405	ENOG4106RZ4	Peptidase U32
D1115_03410	ENOG4105CFP	Peptidase U32
D1115_03420	ENOG4105XPQ	lipid carrier protein
D1115_03425	ENOG4108YYD	acetyltransferase
D1115_03450	ENOG4105EYA	deoxyribonuclease
D1115_03455	ENOG4105D9N	nucleoside
D1115_03460	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
D1115_03465	ENOG4105CMW	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity)
D1115_03470	ENOG4105CZG	Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity)
D1115_03475	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
D1115_03495	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
D1115_03500	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
D1115_03505	ENOG4108IQE	Amp-dependent synthetase and ligase
D1115_03515	ENOG41064T2	transcriptional regulator, lysR family
D1115_03520	ENOG4105CQ4	Transcriptional regulator
D1115_03525	ENOG4105CMR	udp-glucose 4-epimerase
D1115_03530	ENOG4105F0Z	galactose-1-phosphate uridylyltransferase
D1115_03535	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
D1115_03540	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
D1115_03545	ENOG41060NJ	transcriptional regulator
D1115_03565	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
D1115_03570	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
D1115_03580	ENOG4105EJ3	Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA (By similarity)
D1115_03595	ENOG4105X2V	dna damage-inducible protein
D1115_03600	ENOG4105EVZ	LysR family transcriptional regulator
D1115_03610	ENOG4105DSY	exodeoxyribonuclease V, gamma
D1115_03615	ENOG4107QKA	exodeoxyribonuclease V beta
D1115_03620	ENOG4107QYX	exodeoxyribonuclease v alpha
D1115_03700	ENOG4105BZU	Histidine kinase
D1115_03705	ENOG4105BZU	Histidine kinase
D1115_03715	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
D1115_03720	ENOG4105BZU	Histidine kinase
D1115_03795	ENOG4105CUZ	uba thif-type nad fad binding protein
D1115_03800	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
D1115_03805	ENOG4105C9B	Cysteine desulfurase
D1115_03810	ENOG4107S0N	DJ-1 family
D1115_03815	ENOG4108JZF	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
D1115_03820	ENOG4105DRB	nucleoside-specific channel-forming protein
D1115_03840	ENOG4105K6V	RNA polymerase
D1115_03855	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
D1115_03865	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
D1115_03870	ENOG4105M85	Bola protein
D1115_03875	ENOG4105DWQ	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
D1115_03880	ENOG4108J5C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
D1115_03885	ENOG4106I92	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
D1115_03890	ENOG4105F5D	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
D1115_03895	ENOG4108IUB	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
D1115_03900	ENOG4105D26	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway (By similarity)
D1115_03905	ENOG4105CJ2	(LipO)protein
D1115_03920	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
D1115_03925	ENOG4105C9U	ATP-dependent DNA helicase RecQ
D1115_03930	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
D1115_03940	ENOG4105C8J	)-transporter
D1115_03950	ENOG4105W1I	UPF0253 protein
D1115_03960	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
D1115_03965	ENOG4108R96	Methyltransferase, YaeB family
D1115_03970	ENOG4105CFC	Transporter
D1115_03975	ENOG4108UPT	UPF0178 protein
D1115_04000	ENOG4105WP7	tRNA pseudouridine synthase C
D1115_04005	ENOG4105DR9	pseudouridine synthase
D1115_04010	ENOG4108T8E	UPF0325 protein
D1115_04015	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
D1115_04020	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
D1115_04025	ENOG4105CE9	30S ribosomal protein S2
D1115_04030	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
D1115_04035	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
D1115_04040	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
D1115_04045	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
D1115_04050	ENOG4105KNE	Phosphatidate cytidylyltransferase
D1115_04055	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
D1115_04060	ENOG4105DZP	Membrane-associated zinc metalloprotease
D1115_04070	ENOG4108RFI	Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm (By similarity)
D1115_04075	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
D1115_04080	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
D1115_04085	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
D1115_04090	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
D1115_04095	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
D1115_04100	ENOG4105C0B	DNA polymerase III (alpha subunit)
D1115_04105	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
D1115_04110	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
D1115_04115	ENOG4105N7H	Cytochrome
D1115_04120	ENOG4108YZA	Nitrogen regulatory protein pii
D1115_04125	ENOG4107NA1	Endonuclease Exonuclease phosphatase
D1115_04135	ENOG4105E9H	Lytic Murein transglycosylase
D1115_04145	ENOG4105D1A	Methyltransferase
D1115_04150	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
D1115_04155	ENOG4107RZZ	dna polymerase iii epsilon subunit
D1115_04170	ENOG4107QPN	acyl-Coa dehydrogenase
D1115_04175	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
D1115_04180	ENOG4105E7A	Glutamine amidotransferase
D1115_04185	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
D1115_04190	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
D1115_04195	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
D1115_04200	ENOG4105C2W	permease
D1115_04215	ENOG4105CS1	NAD(P)H quinone oxidoreductase
D1115_04220	ENOG4105K89	arsenate reductase
D1115_04225	ENOG4105ERG	peptidase m48, ste24p
D1115_04240	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
D1115_04245	ENOG4105RH4	Glycine cleavage system transcriptional repressor
D1115_04255	ENOG4107EG0	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
D1115_04270	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
D1115_04275	ENOG4105KUZ	arsenate reductase
D1115_04295	ENOG4105QZU	Inner membrane protein YfeZ
D1115_04300	ENOG4105EZR	dyp-type peroxidase family protein
D1115_04315	ENOG4105I03	Flagellin
D1115_04320	ENOG4105I03	Flagellin
D1115_04325	ENOG41063QE	flagellar protein FlaG
D1115_04330	ENOG4107BRV	flagellar capping protein
D1115_04340	ENOG4105MQ3	flagellar protein FliS
D1115_04350	ENOG4108JUA	Transcriptional regulator
D1115_04355	ENOG4105BZU	Histidine kinase
D1115_04360	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
D1115_04365	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
D1115_04375	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
D1115_04385	ENOG4108JIR	Flagellum-specific ATP synthase
D1115_04410	ENOG4105DD5	Flagellar motor switch protein
D1115_04415	ENOG4105CN7	Flagellar biosynthetic protein FliP
D1115_04420	ENOG4105VS8	Flagellar biosynthetic protein fliq
D1115_04425	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
D1115_04430	ENOG4105D00	flagellar biosynthetic protein flhB
D1115_04440	ENOG4105FZW	flagellar biosynthesis regulator FlhF
D1115_04445	ENOG4107R21	site-determining protein
D1115_04450	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
D1115_04455	ENOG4108VYJ	response regulator receiver protein
D1115_04460	ENOG4108KCC	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity)
D1115_04465	ENOG4105CBS	Chea signal transduction histidine kinase
D1115_04475	ENOG4107QJE	Chromosome Partitioning Protein
D1115_04485	ENOG4108V3W	Chemotaxis protein, CheW
D1115_04495	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
D1115_04500	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
D1115_04515	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
D1115_04520	ENOG4105DA4	cytochrome c-type biogenesis protein
D1115_04525	ENOG4107QX9	Thiol disulfide interChange protein
D1115_04530	ENOG4108M1T	Cytochrome c-type biogenesis protein
D1115_04535	ENOG4105KWW	Biogenesis protein
D1115_04540	ENOG410903C	(LipO)protein
D1115_04545	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
D1115_04550	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
D1115_04575	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
D1115_04585	ENOG4107QXK	peptidase
D1115_04590	ENOG4108BY2	phosphohistidine phosphatase
D1115_04600	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
D1115_04605	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
D1115_04610	ENOG4105EN6	Membrane
D1115_04615	ENOG4108BPE	-transporting atpase
D1115_04620	ENOG4105MH2	YfcL protein
D1115_04630	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
D1115_04635	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
D1115_04645	ENOG4108PTX	LysR family Transcriptional regulator
D1115_04650	ENOG4105D05	Receptor
D1115_04670	ENOG4105C5Y	PTS System
D1115_04675	ENOG4105D7K	pfkb domain protein
D1115_04680	ENOG4108HKT	sucrose-6-phosphate hydrolase
D1115_04685	ENOG4105CJ0	Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate (By similarity)
D1115_04690	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
D1115_04700	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
D1115_04705	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
D1115_04710	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
D1115_04720	ENOG4105E96	Colicin v production protein
D1115_04725	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
D1115_04730	ENOG4105EJC	lysr family transcriptional regulator
D1115_04735	ENOG4105I93	response regulator
D1115_04740	ENOG4105WD1	Membrane
D1115_04745	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
D1115_04750	ENOG4107QMP	dna polymerase iii subunits gamma and tau
D1115_04755	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
D1115_04760	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
D1115_04765	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
D1115_04770	ENOG4105KRS	Proteinase inhibitor
D1115_04775	ENOG4108ZZ3	UPF0260 protein
D1115_04780	ENOG4105Y3U	Transglycosylase-associated protein
D1115_04785	ENOG4105D0C	transport protein
D1115_04790	ENOG4105CVK	Glutamate decarboxylase
D1115_04810	ENOG4108XM1	transcriptional regulator AsnC family
D1115_04815	ENOG4105C29	acyl-CoA thioesterase
D1115_04820	ENOG4108MNP	Glycoprotein polysaccharide metabolism
D1115_04835	ENOG4105BZU	Histidine kinase
D1115_04850	ENOG4108Z4U	Ferredoxin
D1115_04860	ENOG4105DZ0	fad dependent oxidoreductase
D1115_04865	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
D1115_04880	ENOG4107SXA	Phosphorylase
D1115_04890	ENOG4108NVR	Methyl-accepting chemotaxis
D1115_04895	ENOG4105K59	histidine triad (HIT) protein
D1115_04915	ENOG4108V15	phosphotransferase enzyme family
D1115_04920	ENOG4105D0Y	UPF0227 protein
D1115_04925	ENOG4105CEP	NADH dehydrogenase
D1115_04940	ENOG4108JA2	transcriptioN-repair coupling factor
D1115_04950	ENOG4105D60	lipoprotein releasing system transmembrane protein
D1115_04955	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
D1115_04960	ENOG4105D60	lipoprotein releasing system transmembrane protein
D1115_04970	ENOG4108EC8	DNA internalization-related competence protein ComEC
D1115_04975	ENOG4105BZ1	(ABC) transporter
D1115_04980	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
D1115_04985	ENOG4105W49	UPF0434 protein
D1115_04990	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
D1115_04995	ENOG4105ED1	spovr family
D1115_05005	ENOG4105CYN	Serine protein kinase
D1115_05010	ENOG4105XWI	UPF0304 protein
D1115_05020	ENOG4105F1A	Pyruvate formate-lyase
D1115_05030	ENOG4105C6N	Formate acetyltransferase
D1115_05045	ENOG4108JEH	abc transporter atp-binding protein
D1115_05050	ENOG4105E89	ABC transporter
D1115_05055	ENOG4105DSP	amino acid AbC transporter
D1115_05065	ENOG4105CGK	Exodeoxyribonuclease III
D1115_05070	ENOG4108URS	primosomal replication protein n''
D1115_05075	ENOG4105EJ9	Membrane
D1115_05080	ENOG4105DVT	helicase
D1115_05095	ENOG4108R99	pseudouridine synthase
D1115_05105	ENOG4105VEQ	Cold shock protein
D1115_05110	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
D1115_05115	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
D1115_05120	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
D1115_05125	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
D1115_05140	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
D1115_05145	ENOG4105RKX	Protein of unknown function (DUF2498)
D1115_05150	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
D1115_05160	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
D1115_05165	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
D1115_05185	ENOG4105HP8	regulator of competence-specific genes
D1115_05190	ENOG4105ETE	Transcriptional regulator (LacI family
D1115_05195	ENOG4109039	Involved in the biogenesis of TorA. Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor (By similarity)
D1115_05200	ENOG4106WF9	DNA-binding transcriptional regulator TorR
D1115_05205	ENOG4107S90	membrAne
D1115_05215	ENOG4105GHU	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity (By similarity)
D1115_05220	ENOG4105DAH	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF (By similarity)
D1115_05225	ENOG4105DUC	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division (By similarity)
D1115_05250	ENOG4105PFA	Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity)
D1115_05255	ENOG4105DA6	Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity)
D1115_05260	ENOG41081XQ	Conserved Protein
D1115_05265	ENOG4105C9M	aspartyl-trna synthetase
D1115_05270	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
D1115_05275	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
D1115_05280	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
D1115_05285	ENOG4105C4M	(Ubiquinol oxidase) subunit I
D1115_05290	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
D1115_05305	ENOG4107YD3	Thioesterase
D1115_05310	ENOG4105E02	MotA TolQ exbB proton channel
D1115_05315	ENOG4105M8F	Biopolymer transport protein exbD tolR
D1115_05325	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
D1115_05330	ENOG4105KCK	Peptidoglycan-associated lipoprotein
D1115_05335	ENOG4105UFD	tol-pal system protein YbgF
D1115_05340	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
D1115_05355	ENOG4105BZU	Histidine kinase
D1115_05370	ENOG4105D70	Integrase catalytic subunit
D1115_05375	ENOG4105F5W	AtP-binding protein
D1115_05380	ENOG4108PZQ	Inner membrane protein YeeR
D1115_05410	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
D1115_05435	ENOG4107RJ1	sodium solute
D1115_05455	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
D1115_05460	ENOG41080XP	Cbs domain
D1115_05465	ENOG4107EJG	GntR family transcriptional regulator
D1115_05470	ENOG4107EJG	GntR family transcriptional regulator
D1115_05475	ENOG4107QI1	Mate efflux family protein
D1115_05480	ENOG4105XEP	YhcH YjgK YiaL family protein
D1115_05485	ENOG4105EY3	heparinase II III family protein
D1115_05490	ENOG4105EY3	heparinase II III family protein
D1115_05495	ENOG4105M5J	Cupin 2, conserved barrel domain protein
D1115_05500	ENOG4107SS6	2-dehydro-3-deoxygluconokinase
D1115_05505	ENOG4108UHU	Aldolase
D1115_05520	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
D1115_05525	ENOG4105FR9	TRNA-(Ms 2 io 6 A)-hydroxylase
D1115_05535	ENOG4107R11	Transcriptional regulator
D1115_05545	ENOG4105DCF	alanine dehydrogenase
D1115_05550	ENOG4105EW9	transcriptional regulator AsnC family
D1115_05560	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
D1115_05565	ENOG4105D1H	recombination factor protein RarA
D1115_05570	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
D1115_05575	ENOG4105KSC	Transcriptional regulator, TraR DksA family
D1115_05580	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
D1115_05585	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
D1115_05595	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
D1115_05600	ENOG4105EWW	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
D1115_05610	ENOG4105D0M	Protease HtpX homolog
D1115_05645	ENOG4105RHG	
D1115_05655	ENOG4107QTF	adenylosuccinate lyase
D1115_05660	ENOG41075W9	High frequency lysogenization protein HflD homolog
D1115_05665	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
D1115_05675	ENOG4107RE1	Inosine-guanosine kinase
D1115_05685	ENOG4107S6Z	Na H antiporter
D1115_05690	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
D1115_05745	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
D1115_05750	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
D1115_05755	ENOG4105C8N	cysteinyl-tRNA synthetase
D1115_05760	ENOG4107104	thymidine kinase
D1115_05765	ENOG4105GFG	DUF218 domain
D1115_05790	ENOG4105TMB	Formate nitrite transporter
D1115_05795	ENOG4105C4B	ABC transporter, permease
D1115_05810	ENOG4108J2R	molybdopterin oxidoreductase
D1115_05825	ENOG4105E2M	Manganese-dependent inorganic pyrophosphatase
D1115_05835	ENOG4108JQ2	peptide transport system atp-binding protein
D1115_05840	ENOG4108JQ3	Peptide ABC transporter ATP-binding protein
D1115_05845	ENOG4108EU3	peptide transport system, permease
D1115_05850	ENOG4108I5W	peptide transport system, permease protein
D1115_05855	ENOG4108J59	Extracellular solute-binding protein, family 5
D1115_05860	ENOG4105E51	psp operon transcriptional activator
D1115_05865	ENOG41087YS	Phage shock protein A
D1115_05870	ENOG4105YYT	phage shock protein B
D1115_05885	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
D1115_05895	ENOG4108R3E	Dna-3-methyladenine glycosylase i
D1115_05900	ENOG4105C28	cystathionine
D1115_05910	ENOG4105C8J	)-transporter
D1115_05920	ENOG4108W1A	pseudouridine synthase
D1115_05930	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
D1115_05935	ENOG4105EJ7	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity)
D1115_05940	ENOG4108JUA	Transcriptional regulator
D1115_05950	ENOG4108T9J	Cdp-alcohol phosphatidyltransferase
D1115_05955	ENOG4108VGW	abc transporter atp-binding protein
D1115_05960	ENOG4105CXZ	ABC transporter, permease
D1115_05965	ENOG4105VNH	ABC transporter solute-binding protein
D1115_05970	ENOG4108RSN	SNARE associated Golgi
D1115_05980	ENOG4105BZ8	glutamate synthase
D1115_05995	ENOG4108ZXC	Two component transcriptional regulator, luxr family
D1115_06005	ENOG4105XZD	Fe-S protein
D1115_06015	ENOG4105CGH	5'-nucleotidase
D1115_06020	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
D1115_06025	ENOG4105EB3	Histidine kinase
D1115_06030	ENOG4105ETX	regulatoR
D1115_06045	ENOG4105I08	Pseudouridine synthase
D1115_06050	ENOG4105C2C	drug resistance transporter, Bcr CflA
D1115_06060	ENOG4107RUZ	Sss sodium solute transporter superfamily
D1115_06070	ENOG4105ETE	Transcriptional regulator (LacI family
D1115_06080	ENOG4107QI1	Mate efflux family protein
D1115_06085	ENOG4108I0Y	(ABC) transporter
D1115_06105	ENOG41067SE	Tetr family transcriptional regulator
D1115_06110	ENOG4107QPN	acyl-Coa dehydrogenase
D1115_06115	ENOG4105RKW	reductase (By
D1115_06125	ENOG41090BQ	Glutaredoxin
D1115_06135	ENOG4106KNT	transcriptional regulator
D1115_06140	ENOG4105DY8	decarboxylase
D1115_06150	ENOG4105DWU	Membrane
D1115_06165	ENOG4105DQ6	Transposase
D1115_06170	ENOG4105IYK	transposase
D1115_06185	ENOG4105BZU	Histidine kinase
D1115_06195	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
D1115_06215	ENOG4108JJ8	(ABC) transporter
D1115_06220	ENOG4108JJ9	ABC, transporter
D1115_06225	ENOG4105C3M	thioredoxin reductase
D1115_06235	ENOG4105C9B	Cysteine desulfurase
D1115_06245	ENOG4105BZU	Histidine kinase
D1115_06250	ENOG4105C8P	)-transporter
D1115_06260	ENOG4107R1I	NAD-dependent malic enzyme
D1115_06275	ENOG4105C8V	SAICAR synthetase
D1115_06295	ENOG4105CDV	Ompa motb domain protein
D1115_06310	ENOG4105CQB	FAD linked oxidase domain protein
D1115_06325	ENOG4105C84	Histidine ammonia-lyase
D1115_06340	ENOG4105CI2	imidazolone-5-propionate hydrolase
D1115_06345	ENOG4105CZE	histidine utilization repressor
D1115_06360	ENOG4105CC9	acyl-Coa dehydrogenase
D1115_06375	ENOG4105BZU	Histidine kinase
D1115_06405	ENOG4108M24	von Willebrand factor, type A
D1115_06415	ENOG41084EC	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease (By similarity)
D1115_06605	ENOG4105C22	threonyL-tRNA synthetase
D1115_06610	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
D1115_06615	ENOG41082NX	50s ribosomal protein l35
D1115_06620	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
D1115_06630	ENOG4105K8R	UPF0145 protein
D1115_06640	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
D1115_06645	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
D1115_06675	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
D1115_06680	ENOG4105CQ7	ATP-dependent helicase
D1115_06690	ENOG4107QI1	Mate efflux family protein
D1115_06695	ENOG4105GIJ	Glycine betaine
D1115_06700	ENOG4108HQS	Glycine betaine
D1115_06705	ENOG4108IJ7	Glycine betaine
D1115_06720	ENOG4105C94	Transporter
D1115_06725	ENOG4108Z24	l-2,4-diaminobutyric acid acetyltransferase
D1115_06730	ENOG4108JPW	Aminotransferase
D1115_06735	ENOG4108Z6K	Catalyzes the circularization of gamma-N-acetyl- alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6- tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant (By similarity)
D1115_06745	ENOG4105HEI	LysR family (Transcriptional regulator
D1115_06750	ENOG4105ECR	NmrA family
D1115_06780	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
D1115_06785	ENOG4108Q79	6-phosphogluconolactonase (EC 3.1.1.31)
D1115_06790	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
D1115_06880	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
D1115_06885	ENOG4105C26	Dehydrogenase
D1115_06900	ENOG4105EJ9	Membrane
D1115_06905	ENOG4108ESY	Metal dependent phosphohydrolase
D1115_06910	ENOG41073TP	transcriptional regulator
D1115_06915	ENOG4105CR4	methylisocitrate lyase
D1115_06920	ENOG4105BZN	citrate synthase
D1115_06925	ENOG4108I0Z	Aconitate hydratase
D1115_06930	ENOG4105C7F	AcnD-accessory protein PrpF
D1115_06935	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
D1115_06950	ENOG410667J	hydrolase
D1115_06955	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
D1115_06960	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
D1115_07000	ENOG4105DR4	Methyltransferase
D1115_07005	ENOG4105C8Q	Methyl-accepting chemotaxis
D1115_07010	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
D1115_07015	ENOG4108Z0T	Part of a sulfur-relay system (By similarity)
D1115_07020	ENOG4108MN8	Membrane
D1115_07025	ENOG4105CDA	abc transporter atp-binding protein
D1115_07030	ENOG4105DRP	amino acid AbC transporter
D1115_07035	ENOG4105EZ7	amino acid ABC transporter
D1115_07040	ENOG4107QXX	ABC transporter
D1115_07050	ENOG4108VPT	UPF0234 protein
D1115_07055	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
D1115_07075	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
D1115_07095	ENOG4105BZ1	(ABC) transporter
D1115_07105	ENOG41073DY	may be a structural element that influences the osmotic activation of ProP at a post-translational level (By similarity)
D1115_07110	ENOG4105CN1	protease
D1115_07120	ENOG4105CD8	aminopeptidase N
D1115_07135	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
D1115_07140	ENOG4108T7E	Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ (By similarity)
D1115_07145	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
D1115_07155	ENOG4105C5H	ABC transporter
D1115_07175	ENOG4105DAN	ATP-dependent protease
D1115_07180	ENOG4108R9Q	Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle. Prevents early segregation of duplicated Ter macrodomains during cell division. Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain (By similarity)
D1115_07230	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
D1115_07250	ENOG4105C59	p-type ATPase
D1115_07265	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
D1115_07270	ENOG4105Q9Y	Universal stress protein
D1115_07275	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
D1115_07295	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
D1115_07300	ENOG4105F38	ABC transporter, permease
D1115_07305	ENOG4105D38	putrescine abc transporter
D1115_07310	ENOG4107RUE	extracellular solute-binding protein family 1
D1115_07315	ENOG4107RUE	extracellular solute-binding protein family 1
D1115_07320	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
D1115_07340	ENOG4105QAX	Iron-sulfur
D1115_07345	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
D1115_07375	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
D1115_07400	ENOG4105BZU	Histidine kinase
D1115_07405	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
D1115_07420	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
D1115_07425	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
D1115_07430	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
D1115_07445	ENOG4106IUH	DTW domain containing protein
D1115_07475	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
D1115_07480	ENOG4105FGM	Fructosamine kinase
D1115_07490	ENOG4108R6K	riboflavin synthase, subunit alpha
D1115_07495	ENOG4107QI1	Mate efflux family protein
D1115_07515	ENOG4105F88	accessory colonization factor AcfD
D1115_07540	ENOG4108YK4	Acid-resistance membrane protein
D1115_07550	ENOG4107QHE	Choloylglycine hydrolase
D1115_07555	ENOG4105Q9Y	Universal stress protein
D1115_07570	ENOG41082AN	stage II sporulation protein
D1115_07595	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
D1115_07600	ENOG4107XU6	Glycosyl transferase (Group 1
D1115_07630	ENOG4108UW5	maltose o-acetyltransferase
D1115_07635	ENOG4107EF8	Glycosyl transferase (Group 1
D1115_07640	ENOG4105D75	Capsular exopolysaccharide family
D1115_07680	ENOG4108RXX	maleylacetoacetate isomerase
D1115_07690	ENOG4105F1J	Homogentisate 1,2-dioxygenase
D1115_07695	ENOG4105E6K	4-Hydroxyphenylpyruvate dioxygenase
D1115_07740	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
D1115_07750	ENOG4108JQ7	(ABC) transporter
D1115_07770	ENOG4105HEI	LysR family (Transcriptional regulator
D1115_07775	ENOG4105F27	Major Facilitator
D1115_07785	ENOG4105CR8	Transcriptional regulator
D1115_07820	ENOG4105C2C	drug resistance transporter, Bcr CflA
D1115_07850	ENOG4108QW8	Purine nucleoside phosphorylase deoD-type
D1115_07855	ENOG4105D38	putrescine abc transporter
D1115_07860	ENOG4105F38	ABC transporter, permease
D1115_07865	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
D1115_07870	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
D1115_07875	ENOG4105CIF	Ornithine Cyclodeaminase
D1115_07885	ENOG41080HI	glycine oxidase
D1115_07890	ENOG4105CTU	Proline racemase
D1115_07915	ENOG4105BZU	Histidine kinase
D1115_07930	ENOG4108VKG	metal-dependent hydrolase
D1115_07940	ENOG4105F04	LysR family Transcriptional regulator
D1115_07975	ENOG4105BZG	amino acid carrier protein
D1115_07980	ENOG410829K	Lysine exporter protein (Lyse ygga)
D1115_07985	ENOG4105CTD	carboxy-peptidase
D1115_07990	ENOG4105D1S	lipid A biosynthesis
D1115_07995	ENOG4105N14	lysine exporter protein LysE YggA
D1115_08000	ENOG4105E5D	amino acid
D1115_08010	ENOG4105CVG	Homoserine O-transsuccinylase
D1115_08015	ENOG41090FY	type IV pilus biogenesis stability protein PilW
D1115_08020	ENOG41080WI	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system (By similarity)
D1115_08025	ENOG4108IU2	vtamin B12-transporter permease
D1115_08030	ENOG4107UI5	Transforms N(2)-succinylglutamate into succinate and glutamate (By similarity)
D1115_08050	ENOG4108UHF	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
D1115_08055	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
D1115_08065	ENOG4105K4T	epimerase
D1115_08075	ENOG4105FDP	GntR family transcriptional regulator
D1115_08080	ENOG4105DM4	PTS System
D1115_08085	ENOG4105C8I	hydrolase, family 38
D1115_08090	ENOG4105EIP	mannose-6-phosphate isomerase
D1115_08110	ENOG4105VAW	lrga family
D1115_08120	ENOG4107T42	This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis (By similarity)
D1115_08125	ENOG4108HH9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
D1115_08130	ENOG4105FQ6	thiopurine methyltransferase
D1115_08140	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
D1115_08150	ENOG41064RH	membrane protein YliF
D1115_08160	ENOG4105CFG	Acts as a chaperone (By similarity)
D1115_08165	ENOG4105CFG	Acts as a chaperone (By similarity)
D1115_08180	ENOG4105BZ1	(ABC) transporter
D1115_08185	ENOG4105BZ1	(ABC) transporter
D1115_08200	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
D1115_08205	ENOG4105E0U	tyrosine-specific transport protein
D1115_08220	ENOG4105EE5	Membrane protein terC
D1115_08230	ENOG41076CZ	activating enzyme
D1115_08235	ENOG4105G0K	glycine radical enzyme YjjI family
D1115_08245	ENOG4105CPI	Metal Dependent Phosphohydrolase
D1115_08250	ENOG4108K0B	C-di-gmp phosphodiesterase
D1115_08255	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
D1115_08260	ENOG4105BZU	Histidine kinase
D1115_08285	ENOG4105W08	virulence gene repressor rsal
D1115_08290	ENOG4105W2W	Cytotoxic translational repressor of toxin-antitoxin stability system
D1115_08295	ENOG4108ZI4	Glyoxalase Bleomycin resistance protein (Dioxygenase
D1115_08645	ENOG4105EC3	peptidase S51, dipeptidase E
D1115_08870	ENOG4108YZS	Had-superfamily hydrolase, subfamily ia, variant 1
D1115_08890	ENOG4105YGK	Pfam:UPF0157
D1115_08925	ENOG4105K4U	addiction module toxin, RelE StbE family
D1115_09140	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
D1115_09290	ENOG4105D9U	N-acetyltransferase
D1115_09305	ENOG4105CM6	amino acid regulated cytosolic protein
D1115_09320	ENOG4105CRQ	synthase (Component I)
D1115_09330	ENOG4105C44	Serine transporter
D1115_09335	ENOG4105EJQ	L-serine dehydratase
D1115_09345	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
D1115_09350	ENOG4105C5S	asparaginyl-tRNA synthetase
D1115_09385	ENOG4105C8Q	Methyl-accepting chemotaxis
D1115_09390	ENOG4105C94	Transporter
D1115_09410	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
D1115_09420	ENOG4105CH5	extracellular solute-binding protein, family 7
D1115_09435	ENOG4105C5X	domain protein
D1115_09440	ENOG4105EAQ	(twin-arginine translocation) pathway signal
D1115_09450	ENOG4107T1C	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity)
D1115_09470	ENOG4105DQ6	Transposase
D1115_09475	ENOG4105DQ6	Transposase
D1115_09480	ENOG4105IYK	transposase
D1115_09485	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
D1115_09490	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
D1115_09500	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
D1115_09505	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
D1115_09525	ENOG4105EVN	Prephenate dehydrogenase
D1115_09530	ENOG4105D3D	Catalyzes the decarboxylation of carboxynorspermidine and carboxyspermidine (By similarity)
D1115_09575	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
D1115_09580	ENOG4105WH1	Two component transcriptional regulator luxr family
D1115_09585	ENOG4105CQ2	DNA polymerase
D1115_09600	ENOG4108W5H	UPF0263 protein
D1115_09605	ENOG4105FE9	pseudouridine synthase
D1115_09610	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
D1115_09615	ENOG4105DB7	PHP domain protein
D1115_09625	ENOG4105CRQ	synthase (Component I)
D1115_09630	ENOG4105DDQ	anthranilate synthase
D1115_09635	ENOG4108I0Q	anthranilate phosphoribosyltransferase
D1115_09640	ENOG4105DK0	Indole-3-glycerol phosphate synthase
D1115_09645	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
D1115_09650	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
D1115_09655	ENOG4105CK2	sodium dicarboxylate symporter
D1115_09660	ENOG4107835	probably involved in intracellular septation (By similarity)
D1115_09665	ENOG4105NAU	thioesterase Superfamily protein
D1115_09670	ENOG4105K9H	YciI-like protein
D1115_09680	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
D1115_09685	ENOG4105DZ2	Transcriptional regulator
D1115_09705	ENOG4105CCT	upf0313 protein
D1115_09710	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
D1115_09720	ENOG4105KME	endoribonuclease L-psp
D1115_09725	ENOG4105WWK	YheO domain protein
D1115_09730	ENOG4105C8Q	Methyl-accepting chemotaxis
D1115_09740	ENOG4105SA9	Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
D1115_09755	ENOG41062D9	Histidine kinase
D1115_09775	ENOG4105EQ2	LysR family Transcriptional regulator
D1115_09780	ENOG4105J12	Multidrug resistance protein mdtN
D1115_09825	ENOG4105N6Y	Thioredoxin
D1115_09830	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
D1115_09835	ENOG4105JQN	Transcriptional regulator
D1115_09840	ENOG4105DHT	Metal Dependent Phosphohydrolase
D1115_09845	ENOG4105CT4	transporter
D1115_09870	ENOG41060NJ	transcriptional regulator
D1115_09880	ENOG4105DY2	Paraquat-inducible protein b
D1115_09885	ENOG4108Q2G	(LipO)protein
D1115_09900	ENOG4108J59	Extracellular solute-binding protein, family 5
D1115_09905	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
D1115_09920	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
D1115_09925	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
D1115_09930	ENOG4105CAT	Cytidine monophosphate kinase
D1115_09935	ENOG4105ERU	peptidase
D1115_09940	ENOG4105UBK	short-chain dehydrogenase reductase
D1115_09960	ENOG4107R88	Chemotaxis protein (CheV)
D1115_09965	ENOG4105DAG	ROK family
D1115_09995	ENOG4105CI1	PTS System
D1115_10000	ENOG4105F8V	Hydrolase, tatD family
D1115_10005	ENOG4107QRG	dna polymerase iii
D1115_10010	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
D1115_10015	ENOG4105HHA	aminodeoxychorismate lyase
D1115_10025	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
D1115_10030	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
D1115_10035	ENOG4105CHR	reductase
D1115_10040	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
D1115_10045	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
D1115_10050	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
D1115_10055	ENOG4105VGS	50s ribosomal protein l32
D1115_10060	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
D1115_10070	ENOG4105EI2	Pseudouridine synthase
D1115_10075	ENOG4105C03	ribonuclease
D1115_10080	ENOG4105CHH	sulfate transporter
D1115_10090	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
D1115_10095	ENOG4108GAE	asmA family
D1115_10100	ENOG4105DBI	uridine monophosphokinase
D1115_10105	ENOG4105D1F	ATP-binding protein
D1115_10110	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
D1115_10120	ENOG4105C05	Multifunctional regulator of fatty acid metabolism (By similarity)
D1115_10125	ENOG4105DKR	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
D1115_10130	ENOG410635M	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
D1115_10135	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
D1115_10140	ENOG4105FBT	Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity)
D1115_10155	ENOG4108JJB	ABC transporter
D1115_10160	ENOG4105C7J	ABC transporter, permease
D1115_10170	ENOG4105PQ6	UPF0208 membrane protein
D1115_10175	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
D1115_10180	ENOG4108DNC	Involved in acetate metabolism (By similarity)
D1115_10185	ENOG4107PU6	Membrane
D1115_10190	ENOG4105CHF	Glutathione S-transferase
D1115_10195	ENOG41067B5	Histone deacetylase superfamily protein
D1115_10200	ENOG4107RUE	extracellular solute-binding protein family 1
D1115_10205	ENOG4108JQ7	(ABC) transporter
D1115_10210	ENOG4105C3U	ABC transporter
D1115_10215	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
D1115_10220	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
D1115_10225	ENOG4107QSI	ABC, transporter
D1115_10230	ENOG4108ZAF	Molybdopterin
D1115_10235	ENOG4105M00	molybdopterin converting factor, subunit 1
D1115_10240	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
D1115_10245	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
D1115_10250	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
D1115_10255	ENOG4105CHW	UPF0052 protein
D1115_10265	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
D1115_10270	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
D1115_10280	ENOG4105C6N	Formate acetyltransferase
D1115_10285	ENOG4105DGN	Electron transport complex
D1115_10290	ENOG4108R3D	Electron transport complex
D1115_10300	ENOG4105D6A	Electron transport complex
D1115_10310	ENOG4105DZB	Electron transport complex
D1115_10315	ENOG4105CSM	endonuclease III
D1115_10320	ENOG4108UYE	Lactoylglutathione lyase
D1115_10325	ENOG4106WH9	Protein of unknown function (DUF2753)
D1115_10330	ENOG4105EIY	sodium-type flagellar protein motY
D1115_10340	ENOG4105D3Y	Na H antiporter
D1115_10350	ENOG4105M2J	Glutaredoxin
D1115_10355	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
D1115_10375	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
D1115_10380	ENOG4105EYW	Ion transport protein
D1115_10390	ENOG4105DFD	Na H antiporter
D1115_10410	ENOG4106V8H	Nucleoid-associated protein
D1115_10415	ENOG4105YDX	UPF0352 protein
D1115_10430	ENOG4105DGU	Histone deacetylase
D1115_10435	ENOG4105CXK	mandelate racemase muconate lactonizing
D1115_10445	ENOG4105CTX	dehydratase
D1115_10470	ENOG41069NU	Nitroreductase
D1115_10475	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
D1115_10480	ENOG4105D07	Signal peptide peptidase, SppA
D1115_10485	ENOG4105HDK	L-asparaginase
D1115_10490	ENOG4105VUT	cytoplasmic protein
D1115_10500	ENOG4105E0X	reductase
D1115_10505	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
D1115_10510	ENOG4105DSB	aldose 1-epimerase
D1115_10515	ENOG4105DHI	Methyltransferase
D1115_10530	ENOG4105C94	Transporter
D1115_10535	ENOG4105BZS	acriflavin resistance protein
D1115_10540	ENOG4105EP1	Efflux transporter rnd family, mfp subunit
D1115_10595	ENOG4105HMI	Membrane
D1115_10610	ENOG4105DNI	Converts SHCHC to OSB (By similarity)
D1115_10615	ENOG4108IPT	Naphthoate synthase
D1115_10620	ENOG4107J5P	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity)
D1115_10625	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
D1115_10630	ENOG4105E4F	Isochorismate synthase
D1115_10635	ENOG4105CHM	Aminotransferase
D1115_10660	ENOG41083P1	competence protein ComEA helix-hairpin-helix repeat protein
D1115_10665	ENOG4105EIN	peptidylprolyl cis-trans isomerase
D1115_10670	ENOG4105K70	DNA-binding protein
D1115_10675	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
D1115_10680	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
D1115_10690	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
D1115_10700	ENOG4105CNG	UPF0061 protein
D1115_10720	ENOG4107ZYR	domain protein
D1115_10725	ENOG4105C1J	atp-dependent rna helicase
D1115_10745	ENOG4105C8Q	Methyl-accepting chemotaxis
D1115_10750	ENOG4105DFP	Integrase
D1115_10825	ENOG4105D8D	Type III
D1115_10860	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
D1115_10865	ENOG4105D9N	nucleoside
D1115_10875	ENOG4105CVE	Lytic murein transglycosylase
D1115_10885	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
D1115_10890	ENOG4107QMS	site-determining protein
D1115_10895	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
D1115_10905	ENOG4105CEY	Amp-dependent synthetase and ligase
D1115_10910	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
D1115_10925	ENOG41072GX	Peptidase M22 Glycoprotease
D1115_10930	ENOG4105DVT	helicase
D1115_10935	ENOG4105CIY	formyltetrahydrofolate deformylase
D1115_10940	ENOG4106ZCM	YecM protein
D1115_10945	ENOG4105C75	arginyL-tRNA synthetase
D1115_10965	ENOG4105XFK	Ferrous iron transport protein A
D1115_10975	ENOG4105NXV	High-affinity zinc uptake system protein
D1115_10985	ENOG4105FAV	ABC, transporter
D1115_10990	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
D1115_10995	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
D1115_11000	ENOG4105C7S	Dehydrogenase
D1115_11005	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
D1115_11010	ENOG4105E33	succinate dehydrogenase
D1115_11015	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
D1115_11020	ENOG4105N1I	succinate dehydrogenase, hydrophobic membrane anchor protein
D1115_11025	ENOG4108UTY	succinate dehydrogenase, cytochrome b556 subunit
D1115_11030	ENOG4105BZN	citrate synthase
D1115_11035	ENOG4107QNR	UPF0135 protein
D1115_11045	ENOG4107QIX	Phosphoglucomutase (EC 5.4.2.2
D1115_11050	ENOG4107CDU	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated (By similarity)
D1115_11065	ENOG4105MHQ	Low-potential electron donor to a number of redox enzymes (By similarity)
D1115_11075	ENOG41090R7	Ferric uptake
D1115_11080	ENOG4105CX6	glutaminyL-tRNA synthetase
D1115_11085	ENOG4105CI1	PTS System
D1115_11095	ENOG4105CE4	GlcNAc 6-P deacetylase
D1115_11105	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
D1115_11110	ENOG4105CAQ	asparagine synthetase
D1115_11115	ENOG4105MDZ	Transcriptional activator rfaH
D1115_11120	ENOG4105DUX	Transporter
D1115_11125	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
D1115_11130	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
D1115_11135	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
D1115_11140	ENOG4108DQ1	activator toxR
D1115_11160	ENOG4108RE9	Phosphodiesterase
D1115_11170	ENOG4105ECP	epimerase
D1115_11175	ENOG4105E1F	short-chain dehydrogenase reductase
D1115_11185	ENOG4107QR8	Thioredoxin
D1115_11190	ENOG4107QX8	SPFH domain, Band 7 family protein
D1115_11195	ENOG4105G5H	Membrane
D1115_11215	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
D1115_11225	ENOG4105EXN	Sulfate transport protein CysZ
D1115_11230	ENOG4105C6T	cysteine synthase
D1115_11240	ENOG4105KZ7	phosphocarrier protein hpr
D1115_11245	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
D1115_11250	ENOG4105C5Y	PTS System
D1115_11255	ENOG4105I03	Flagellin
D1115_11260	ENOG4105I03	Flagellin
D1115_11275	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
D1115_11280	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
D1115_11285	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
D1115_11290	ENOG4105CGA	flagellar basal-body rod protein FlgG
D1115_11295	ENOG4108KPB	Flagellar basal-body rod protein FlgF
D1115_11300	ENOG4105BZE	flagellar hook protein, FlgE
D1115_11305	ENOG4105W00	Flagellar hook capping protein
D1115_11310	ENOG4108ZC9	flagellar basal-body rod protein flgc
D1115_11315	ENOG4105K88	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
D1115_11320	ENOG4105BZU	Histidine kinase
D1115_11325	ENOG4107R88	Chemotaxis protein (CheV)
D1115_11370	ENOG4105UYK	outer membrane protein a
D1115_11375	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
D1115_11400	ENOG4105E2D	ec 3.2.1.52
D1115_11420	ENOG4108DG9	Smr protein MutS2
D1115_11425	ENOG4105FE9	pseudouridine synthase
D1115_11430	ENOG4108Z66	YbaK ebsC protein
D1115_11435	ENOG4105CGH	5'-nucleotidase
D1115_11440	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
D1115_11445	ENOG41063JG	Transcriptional regulator
D1115_11450	ENOG4108YY7	Invasion gene expression up-regulator SirB
D1115_11455	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
D1115_11460	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
D1115_11465	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
D1115_11475	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
D1115_11480	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
D1115_11485	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
D1115_11490	ENOG4105C3G	gtp-binding protein
D1115_11600	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
D1115_11615	ENOG4105C9A	Phoh family
D1115_11625	ENOG4108JU5	Magnesium and cobalt efflux protein
D1115_11630	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
D1115_11635	ENOG4107PAI	alpha helical protein
D1115_11640	ENOG4105C8T	Leucyl-tRNA synthetase
D1115_11645	ENOG4108U2H	Rare lipoprotein B
D1115_11655	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
D1115_11660	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
D1115_11665	ENOG4105CJN	penicillin-binding protein
D1115_11670	ENOG4105CNI	cell division protein FtsW
D1115_11675	ENOG4105K6T	rare lipoprotein A
D1115_11680	ENOG4105DZ1	carboxypeptidase
D1115_11685	ENOG4108Z43	UPF0250 protein
D1115_11690	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
D1115_11695	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
D1115_11700	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
D1115_11705	ENOG4108JYZ	YitT family
D1115_11710	ENOG4105CG3	alpha amylase, catalytic region
D1115_11715	ENOG4105C5Y	PTS System
D1115_11720	ENOG4105D4X	repressor
D1115_11725	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
D1115_11730	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
D1115_11735	ENOG4108UMI	ABC transporter, permease
D1115_11740	ENOG4105D01	(LipO)protein
D1115_11745	ENOG4105EXF	Zn-ribbon-containing, possibly nucleic-acid-binding protein
D1115_11750	ENOG4108T6E	Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function (By similarity)
D1115_11755	ENOG4107R1K	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
D1115_11765	ENOG4105BZU	Histidine kinase
D1115_11770	ENOG4105EWT	decarboxylase family
D1115_11775	ENOG4105CIQ	May have a role in processing of nucleic acids. It is probably not an exonuclease
D1115_11780	ENOG4105EZ6	Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA (By similarity)
D1115_11785	ENOG4105M08	Membrane
D1115_11800	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
D1115_11805	ENOG4106VK6	Flagellar motor protein
D1115_11810	ENOG4105E14	MotA TolQ exbB proton channel
D1115_11815	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
D1115_11820	ENOG4105CTB	Polyprenyl synthetase
D1115_11825	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
D1115_11830	ENOG4108ZAI	phosphatidylglycerophosphatase a
D1115_11835	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
D1115_11840	ENOG4107YIM	Involved in the transcription termination process (By similarity)
D1115_11845	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
D1115_11860	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
D1115_11865	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
D1115_11870	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
D1115_11875	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
D1115_11880	ENOG4108UVK	Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes. Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32 (By similarity)
D1115_11885	ENOG4108DJV	Fermentation respiration switch protein
D1115_11890	ENOG4105DYA	Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity)
D1115_11900	ENOG4105C7N	Xanthine uracil vitamin C permease
D1115_11905	ENOG4105CIN	aminoacyl-histidine dipeptidase
D1115_11925	ENOG4108ETH	Formylglycinamide ribotide synthetase
D1115_11930	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
D1115_11945	ENOG4105CFC	Transporter
D1115_11975	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
D1115_11980	ENOG4105CFG	Acts as a chaperone (By similarity)
D1115_11985	ENOG4107QJT	sodium dicarboxylate symporter
D1115_11990	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
D1115_11995	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
D1115_12000	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
D1115_12005	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
D1115_12010	ENOG4105VDB	UPF0125 protein
D1115_12015	ENOG4108Z1B	Cyclase dehydrase
D1115_12020	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
D1115_12030	ENOG4105DFP	Integrase
D1115_12065	ENOG4105DZR	Type I site-specific deoxyribonuclease
D1115_12210	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
D1115_12215	ENOG4108IQK	o-acetylhomoserine
D1115_12220	ENOG4107RSM	transcriptional regulator
D1115_12225	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
D1115_12235	ENOG4105BZG	amino acid carrier protein
D1115_12240	ENOG4106HK8	GPR1 FUN34 yaaH family protein
D1115_12245	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
D1115_12250	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
D1115_12255	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
D1115_12270	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
D1115_12275	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
D1115_12280	ENOG4105N21	Membrane
D1115_12285	ENOG4105CUT	histidyl-tRNA synthetase
D1115_12290	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
D1115_12300	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
D1115_12305	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
D1115_12310	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
D1115_12315	ENOG4105WVQ	Fe-S assembly protein IscX
D1115_12320	ENOG4108ZIT	Ferredoxin, 2FE-2S
D1115_12325	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
D1115_12330	ENOG4108SWN	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA (By similarity)
D1115_12335	ENOG4108Z4V	iron-sulfur cluster assembly
D1115_12340	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
D1115_12345	ENOG4105C3J	Cysteine desulfurase
D1115_12350	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
D1115_12355	ENOG4105CVS	RNA methyltransferase TrmH family, group 1
D1115_12360	ENOG4105ECY	inositol monophosphatase
D1115_12365	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
D1115_12370	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
D1115_12375	ENOG4105VIE	preprotein translocase, subunit YajC
D1115_12380	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
D1115_12385	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
D1115_12395	ENOG4105W87	Cbs domain
D1115_12400	ENOG4108I9X	Isocitrate lyase
D1115_12405	ENOG4107QP3	malate synthase g
D1115_12410	ENOG4105C5Q	Transcriptional regulator
D1115_12415	ENOG4105D3R	alkyl hydroperoxide reductase
D1115_12420	ENOG4106N3A	copper homeostasis protein cutc
D1115_12425	ENOG4105CSR	polyphosphate kinase 2
D1115_12450	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
D1115_12455	ENOG4105E2Z	phosphate ABC transporter (Permease
D1115_12470	ENOG4105C9X	ppx gppa phosphatase
D1115_12480	ENOG4105BZU	Histidine kinase
D1115_12485	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
D1115_12495	ENOG4105DH7	May be involved in recombination (By similarity)
D1115_12500	ENOG4105CFP	Peptidase U32
D1115_12505	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
D1115_12565	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
D1115_12570	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
D1115_12575	ENOG4105C34	Pseudouridine synthase
D1115_12580	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
D1115_12590	ENOG4108WPH	sigma 54 modulation protein ribosomal protein S30EA
D1115_12600	ENOG4108K16	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
D1115_12605	ENOG4105R9M	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region (By similarity)
D1115_12610	ENOG4107SC1	transglycosylase
D1115_12615	ENOG4105C5H	ABC transporter
D1115_12630	ENOG4105EHE	chorismate mutase- prephenate dehydrogenase
D1115_12635	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
D1115_12640	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
D1115_12645	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
D1115_12650	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
D1115_12670	ENOG4108HRK	Histidine kinase
D1115_12675	ENOG4108NEV	two component transcriptional regulator, LytTR family
D1115_12680	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
D1115_12685	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
D1115_12690	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
D1115_12695	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
D1115_12700	ENOG4105DTN	riboflavin biosynthesis protein ribF
D1115_12705	ENOG4105CJR	Integral membrane protein (MviN
D1115_12710	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
D1115_12715	ENOG41080HT	Transcriptional regulator, arsr family
D1115_12720	ENOG41063Z6	transcriptional regulator, lysR family
D1115_12730	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
D1115_12735	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
D1115_12740	ENOG4105HF0	Membrane
D1115_12745	ENOG4108HRM	phosphoenolpyruvate--protein phosphotransferase
D1115_12750	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
D1115_12760	ENOG4105IRT	Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair (By similarity)
D1115_12770	ENOG4105CPC	Aldo Keto reductase
D1115_12785	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
D1115_12790	ENOG4105CRK	lysyL-tRNA synthetase
D1115_12800	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
D1115_12805	ENOG4105T95	Thiol disulfide interChange protein
D1115_12810	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
D1115_12815	ENOG41071R3	Low-potential electron donor to a number of redox enzymes (By similarity)
D1115_12820	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
D1115_12825	ENOG4107S47	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (By similarity)
D1115_12830	ENOG4105C1J	atp-dependent rna helicase
D1115_12835	ENOG4105D1Q	UPF0246 protein
D1115_12840	ENOG4105BZG	amino acid carrier protein
D1115_12855	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
D1115_12865	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
D1115_12870	ENOG4108VKA	Acts as a radical domain for damaged PFL and possibly other radical proteins (By similarity)
D1115_12875	ENOG4105D98	threonine synthase
D1115_12880	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
D1115_12895	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
D1115_12920	ENOG4105BZU	Histidine kinase
D1115_12925	ENOG4105N5T	Radical SAM Protein
D1115_12940	ENOG4105CBC	glutamate synthase
D1115_12945	ENOG4105BZ8	glutamate synthase
D1115_12955	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
D1115_12970	ENOG4105EN6	Membrane
D1115_12975	ENOG4105VP0	transcriptional regulator, lysR family
D1115_12980	ENOG4105EJ9	Membrane
D1115_12985	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
D1115_12990	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
D1115_12995	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
D1115_13000	ENOG4105M6F	mutator MutT protein
D1115_13015	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
D1115_13020	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
D1115_13025	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
D1115_13030	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
D1115_13035	ENOG4105DFU	Cell wall formation (By similarity)
D1115_13040	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
D1115_13050	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
D1115_13055	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
D1115_13060	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
D1115_13065	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
D1115_13070	ENOG4105CJN	penicillin-binding protein
D1115_13075	ENOG41063Y6	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
D1115_13080	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
D1115_13095	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
D1115_13105	ENOG41082RQ	UPF0102 protein
D1115_13110	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
D1115_13115	ENOG4105W4M	Transport-associated protein
D1115_13120	ENOG4105KB2	stringent starvation protein b
D1115_13125	ENOG4107MKT	Stringent starvation protein a
D1115_13130	ENOG4105EIX	cytochrome c1
D1115_13135	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
D1115_13140	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
D1115_13145	ENOG4108UJD	30S ribosomal protein S9
D1115_13150	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
D1115_13160	ENOG4105D6Z	AFG1 family ATPase
D1115_13165	ENOG4108W2Q	Cytochrome d ubiquinol oxidase subunit III
D1115_13170	ENOG4105C0H	protease
D1115_13180	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
D1115_13185	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
D1115_13190	ENOG4105IPS	esterase
D1115_13195	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
D1115_13200	ENOG4108SX3	cytoplasmic protein
D1115_13205	ENOG41087AY	ADP-Ribose pyrophosphatase
D1115_13210	ENOG4105DFG	type I secretion outer membrane protein
D1115_13215	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
D1115_13220	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
D1115_13225	ENOG4105C8Q	Methyl-accepting chemotaxis
D1115_13230	ENOG4105I7R	Adenylate cyclase
D1115_13235	ENOG4107IX6	phosphate transport regulator
D1115_13240	ENOG4105CJ3	phosphate transporter
D1115_13245	ENOG4106MWK	domain protein
D1115_13260	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
D1115_13270	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
D1115_13275	ENOG4107ZVW	dihydroneopterin aldolase
D1115_13280	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
D1115_13285	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
D1115_13290	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
D1115_13295	ENOG4105VCC	30S ribosomal protein S21
D1115_13300	ENOG4105KTH	gatB Yqey
D1115_13310	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
D1115_13330	ENOG4105HF0	Membrane
D1115_13345	ENOG4105W3H	MtN3 and saliva related transmembrane protein
D1115_13365	ENOG4105EG2	ABC transporter, permease
D1115_13375	ENOG4107FKK	extracellular solute-binding protein family 1
D1115_13385	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
D1115_13390	ENOG4108IJ9	(ABC) transporter
D1115_13400	ENOG4105C4X	radical SAM domain protein
D1115_13410	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
D1115_13415	ENOG410804X	Transcriptional regulator
D1115_13420	ENOG4105CA9	Pyruvate kinase
D1115_13435	ENOG4108ZP8	Acetolactate synthase small subunit
D1115_13440	ENOG4105C7K	acetolactate synthase
D1115_13450	ENOG41064T2	transcriptional regulator, lysR family
D1115_13475	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
D1115_13480	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
D1115_13485	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
D1115_13490	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
D1115_13500	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
D1115_13505	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
D1115_13510	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
D1115_13520	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
D1115_13525	ENOG4105NWN	ApaG protein
D1115_13530	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
D1115_13535	ENOG4108YYV	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity)
D1115_13540	ENOG4107XM3	UPF0442 protein
D1115_13545	ENOG4105DWK	Membrane
D1115_13550	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
D1115_13555	ENOG4105K46	50S ribosomal protein l27
D1115_13560	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
D1115_13565	ENOG4105EAH	synthase
D1115_13575	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
D1115_13580	ENOG410682Y	Regulates arginine biosynthesis genes (By similarity)
D1115_13605	ENOG4107T0D	ABC, transporter
D1115_13610	ENOG4106SMU	thiamine transporter membrane protein
D1115_13615	ENOG4105DP9	ABC transporter
D1115_13620	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
D1115_13625	ENOG4105DFU	Cell wall formation (By similarity)
D1115_13630	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
D1115_13635	ENOG4105F0N	pyrophosphate phospho-hydrolase
D1115_13640	ENOG41066HZ	AIG2-like family
D1115_13650	ENOG4105CFU	surface antigen
D1115_13655	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
D1115_13665	ENOG4108UUE	Transcriptional regulator
D1115_13680	ENOG4108I0Y	(ABC) transporter
D1115_13700	ENOG4108I67	Catalyzes the synthesis of activated sulfate (By similarity)
D1115_13710	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
D1115_13715	ENOG4105C11	sulfate adenylyltransferase), subunit 2
D1115_13720	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
D1115_13725	ENOG4107RNS	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic
D1115_13735	ENOG4105C1J	atp-dependent rna helicase
D1115_13740	ENOG4107YB6	acetyltransferase, (GNAT) family
D1115_13750	ENOG4108V1T	peptidylprolyl cis-trans isomerase
D1115_13760	ENOG4108ZT0	50S ribosomal protein l17
D1115_13765	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
D1115_13770	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
D1115_13775	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
D1115_13780	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
D1115_13785	ENOG41067V7	50S ribosomal protein L36
D1115_13790	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
D1115_13795	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
D1115_13800	ENOG4105VPB	50S ribosomal protein L30
D1115_13805	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
D1115_13815	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
D1115_13820	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
D1115_13825	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
D1115_13830	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
D1115_13840	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
D1115_13845	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
D1115_13850	ENOG41083MP	50s ribosomal protein l29
D1115_13855	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
D1115_13860	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
D1115_13865	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
D1115_13870	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
D1115_13875	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
D1115_13880	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
D1115_13885	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
D1115_13890	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
D1115_13895	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
D1115_13900	ENOG4105VFB	Binds the 23S rRNA (By similarity)
D1115_13905	ENOG4105C25	Primosomal protein n'
D1115_13910	ENOG4105ETE	Transcriptional regulator (LacI family
D1115_13920	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
D1115_13925	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
D1115_13935	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
D1115_13940	ENOG41065UX	Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA (By similarity)
D1115_13945	ENOG4105CBT	Fructose-1,6-bisphosphatase
D1115_13975	ENOG4105CP7	Triose-phosphate isomerase
D1115_13995	ENOG4105CY0	Metallo-Beta-Lactamase
D1115_14030	ENOG4105EIP	mannose-6-phosphate isomerase
D1115_14035	ENOG4106ECQ	phosphomannomutase
D1115_14040	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
D1115_14045	ENOG4105FGF	GDP-mannose mannosyl hydrolase
D1115_14050	ENOG4105C30	Nad-dependent epimerase dehydratase
D1115_14070	ENOG4105E2K	Glycosyl transferase (Group 1
D1115_14085	ENOG4105ECJ	Glycosyl Transferase
D1115_14120	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
D1115_14160	ENOG4108MDC	(LipO)protein
D1115_14180	ENOG4105CUI	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity)
D1115_14195	ENOG4105XA0	heptosyltransferase ii
D1115_14235	ENOG4105CHR	reductase
D1115_14245	ENOG4108P1X	synthase
D1115_14265	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
D1115_14270	ENOG4108W7E	Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position (By similarity)
D1115_14275	ENOG41080IJ	Diacylglycerol kinase
D1115_14280	ENOG4105DKP	glycosyl transferase, family 9
D1115_14285	ENOG4106WTF	Glycosyl transferase, family 2
D1115_14295	ENOG4108JMC	lipopolysaccharide core biosynthesis protein
D1115_14305	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
D1115_14315	ENOG4108I6E	Sulfatase
D1115_14325	ENOG4105KDC	50s ribosomal protein l28
D1115_14335	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
D1115_14340	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
D1115_14350	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
D1115_14355	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
D1115_14360	ENOG4105DSJ	YicC domain protein
D1115_14370	ENOG4105DWP	Membrane
D1115_14385	ENOG4108JQ7	(ABC) transporter
D1115_14395	ENOG4107QRA	Extracellular solute-binding protein, family 5
D1115_14400	ENOG4108IYQ	Binding-protein-dependent transport systems inner membrane component
D1115_14405	ENOG4108I5X	binding-protein-dependent transport systems inner membrane Component
D1115_14430	ENOG4109015	Biopolymer transport protein exbD tolR
D1115_14445	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
D1115_14450	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
D1115_14455	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
D1115_14460	ENOG4105FE8	tRNA (Guanosine-2'-O-)-methyltransferase
D1115_14465	ENOG4105CB5	ATP-dependent DNA helicase recG
D1115_14470	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
D1115_14475	ENOG4105C2W	permease
D1115_14480	ENOG4105E0F	Histidine kinase
D1115_14485	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
D1115_14500	ENOG4105BZM	domain protein
D1115_14510	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
D1115_14515	ENOG4105MJ2	Competence protein
D1115_14520	ENOG4107RUK	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins (By similarity)
D1115_14535	ENOG4105PIC	general secretion pathway protein N
D1115_14540	ENOG4105U1E	general secretion pathway protein M
D1115_14545	ENOG4108BY5	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins (By similarity)
D1115_14550	ENOG4108RTD	type II secretion system protein K
D1115_14555	ENOG4108WWZ	General secretion pathway protein J
D1115_14570	ENOG4108VAU	general secretion pathway protein G
D1115_14575	ENOG4105D7Q	type ii secretion system
D1115_14580	ENOG4107QHF	type ii secretion system protein e
D1115_14595	ENOG4105VEJ	Heat shock protein
D1115_14600	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
D1115_14605	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
D1115_14615	ENOG4105SUU	thioesterase domain
D1115_14620	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
D1115_14625	ENOG4107S2Z	UPF0761 membrane protein
D1115_14640	ENOG4105CI3	gtp-binding protein typa
D1115_14645	ENOG4105C5F	glutamine synthetase
D1115_14655	ENOG4105CUX	Signal transduction histidine kinase
D1115_14660	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
D1115_14670	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
D1115_14675	ENOG4105D4P	Coproporphyrinogen iii oxidase
D1115_14685	ENOG4105ZR3	A GTPase-activating protein (GAP) that modifies Der EngA GTPase function. May play a role in ribosome biogenesis (By similarity)
D1115_14700	ENOG4106RE7	Cytochrome
D1115_14705	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
D1115_14715	ENOG4105C2M	dna polymerase I
D1115_14730	ENOG4105D52	delta-aminolevulinic acid dehydratase
D1115_14735	ENOG4105F8V	Hydrolase, tatD family
D1115_14740	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
D1115_14745	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
D1115_14750	ENOG4105WKS	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
D1115_14755	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
D1115_14760	ENOG4105JC1	sterol-binding domain protein
D1115_14770	ENOG4105CGY	Dna recombination protein
D1115_14780	ENOG4105BZU	Histidine kinase
D1115_14785	ENOG4105CBX	hi0933 family
D1115_14790	ENOG4108V6B	universal stress protein B
D1115_14795	ENOG41090A1	ferritin
D1115_14805	ENOG4105EMK	carboxylate amino acid amine transporter
D1115_14815	ENOG4105FFN	Specifically methylates the guanosine in position 1516 of 16S rRNA (By similarity)
D1115_14820	ENOG4108VVK	transcriptional Regulator, AsnC
D1115_14825	ENOG4105DGW	oligopeptidase A
D1115_14830	ENOG4105D6S	protein involved in catabolism of external DNA
D1115_14835	ENOG4105DC8	reductase
D1115_14840	ENOG4108UHU	Aldolase
D1115_14845	ENOG4105C6Z	Gluconate
D1115_14850	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
D1115_14855	ENOG4105C01	Dihydroxy-acid dehydratase
D1115_14865	ENOG41090TI	Catalyzes the excretion of spermidine (By similarity)
D1115_14870	ENOG41064T2	transcriptional regulator, lysR family
D1115_14875	ENOG4105DIQ	Transcriptional regulator
D1115_14910	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
D1115_14915	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
D1115_14920	ENOG4105DEF	Extracellular solute-binding protein, family 5
D1115_14925	ENOG4108JQ6	ABC transporter
D1115_14965	ENOG4105MPD	Cytochrome
D1115_14970	ENOG4105C4R	Atp-dependent dna helicase
D1115_14975	ENOG4107Z3H	Transcriptional regulator, TetR family
D1115_14980	ENOG410624X	efflux transporter, rnd family, mfp subunit
D1115_14985	ENOG4105BZS	acriflavin resistance protein
D1115_14995	ENOG4105W0Z	cytoplasmic protein
D1115_15000	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
D1115_15055	ENOG4105SG3	Protein of unknown function (DUF1488)
D1115_15060	ENOG4105E2X	shikimate dehydrogenase
D1115_15075	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
D1115_15115	ENOG4105C1A	potassium transporter peripheral membrane
D1115_15130	ENOG4108UT2	hemolysin iii
D1115_15145	ENOG4105PC1	Conserved Protein
D1115_15175	ENOG4105C0P	Mg chelatase subunit ChlI
D1115_15185	ENOG4105P3Y	Acetolactate synthase 2 regulatory subunit
D1115_15190	ENOG4105CM2	brancheD-chain amino acid aminotransferase
D1115_15195	ENOG4105C01	Dihydroxy-acid dehydratase
D1115_15200	ENOG4105C7B	Threonine dehydratase
D1115_15210	ENOG4105CZQ	inner membrane transport protein YdhC
D1115_15215	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
D1115_15220	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
D1115_15225	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
D1115_15230	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
D1115_15235	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
D1115_15240	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
D1115_15250	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
D1115_15260	ENOG410684E	atp synthase
D1115_15265	ENOG4105FA0	parb-like partition protein
D1115_15270	ENOG4107QJE	Chromosome Partitioning Protein
D1115_15275	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
D1115_15280	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
D1115_15310	ENOG4105CNI	cell division protein FtsW
D1115_15320	ENOG4105Y49	secretion protein, HlyD family
D1115_15325	ENOG4105CR8	Transcriptional regulator
D1115_15335	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
D1115_15355	ENOG4108HRK	Histidine kinase
D1115_15360	ENOG4108VAC	response regulator
D1115_15370	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
D1115_15390	ENOG4107ZT5	Thiol disulfide interchange protein
D1115_15395	ENOG4108ZX6	Electron transport protein SCO1 SenC
D1115_15435	ENOG4105D6U	Sodium Glutamate Symporter
D1115_15445	ENOG4105DVE	abc transporter atp-binding protein
D1115_15450	ENOG4105D6U	Sodium Glutamate Symporter
D1115_15475	ENOG4105ENH	Sulfatase
D1115_15485	ENOG4105D2N	Aldolase
D1115_15490	ENOG4107SS6	2-dehydro-3-deoxygluconokinase
D1115_15495	ENOG4108UHU	Aldolase
D1115_15540	ENOG4105Y49	secretion protein, HlyD family
D1115_15600	ENOG4105CBG	Sulfatase
D1115_15605	ENOG4105E98	transcriptional regulator DeoR family
D1115_15610	ENOG4105C6Q	that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of
D1115_15620	ENOG4108RG5	PTS system N-acetylgalactosamine-specific transporter subunit IIB
D1115_15625	ENOG4105ETZ	PTS System
D1115_15630	ENOG4105F3R	pts system mannose fructose sorbose family iid
D1115_15635	ENOG4108YTN	IIa component
D1115_15640	ENOG4105CE4	GlcNAc 6-P deacetylase
D1115_15650	ENOG4105CHR	reductase
D1115_15670	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
D1115_15695	ENOG4105D03	DNA-3-methyladenine glycosylase II
D1115_15700	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
D1115_15715	ENOG4105DN9	Na H antiporter
D1115_15740	ENOG4105NBK	UPF0345 protein
D1115_15755	ENOG4105GD4	(Histidine triad) protein
D1115_15785	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
D1115_15820	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
D1115_15830	ENOG4108JQ7	(ABC) transporter
D1115_15840	ENOG41060NJ	transcriptional regulator
D1115_15850	ENOG41060NJ	transcriptional regulator
D1115_15855	ENOG4105ECQ	AraC Family Transcriptional Regulator
D1115_15860	ENOG4107RV5	Glycosyl hydrolase family 3 N-terminal domain protein
D1115_15865	ENOG4105UQX	Mate efflux family protein
D1115_15870	ENOG4105CH5	extracellular solute-binding protein, family 7
D1115_15875	ENOG4105D3G	Pseudouridine synthase
D1115_15880	ENOG4108HCJ	Hydrolase
D1115_15890	ENOG4108KHX	Diguanylate cyclase
D1115_15900	ENOG4105KAF	membrAne
D1115_15915	ENOG4108MUX	N-hydroxyarylamine O-acetyltransferase
D1115_15920	ENOG4105CC0	LysR family Transcriptional regulator
D1115_15935	ENOG4105EW9	transcriptional regulator AsnC family
D1115_15945	ENOG410814C	multidrug resistance protein
D1115_15975	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
D1115_15995	ENOG4105C8Q	Methyl-accepting chemotaxis
D1115_16045	ENOG4105CUW	cytochrome C-TYPE protein
D1115_16050	ENOG4108J2R	molybdopterin oxidoreductase
D1115_16060	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
D1115_16065	ENOG4105C4U	4-methyl-5-beta-hydroxyethylthiazole kinase
D1115_16070	ENOG4105ETU	transcriptional activator (TenA
D1115_16075	ENOG4107Z6I	Thiamine biosynthesis protein
D1115_16080	ENOG4105Y36	Binding-protein-dependent transport systems, inner membrane component
D1115_16085	ENOG4108YI8	ABC transporter
D1115_16090	ENOG4105DWF	phosphomethylpyrimidine kinase
D1115_16105	ENOG4108TEM	pseudouridine methyltransferase
D1115_16165	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
D1115_16245	ENOG4108YYI	Protein of unknown function (DUF2810)
D1115_16260	ENOG4107VXM	glycerophosphoryl diester phosphodiesterase
D1115_16265	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
D1115_16295	ENOG4109015	Biopolymer transport protein exbD tolR
D1115_16315	ENOG4105FCK	Membrane
D1115_16320	ENOG4105CUG	Oligopeptidase b
D1115_16325	ENOG4105E5M	Multidrug resistance protein D
D1115_16330	ENOG4105CYW	agmatinase
D1115_16335	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
D1115_16345	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
D1115_16350	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
D1115_16355	ENOG4108WAV	Transcriptional regulator
D1115_16375	ENOG4105CQZ	Histidine kinase
D1115_16390	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
D1115_16405	ENOG4105D5U	fad dependent oxidoreductase
D1115_16420	ENOG4105C0F	tryptophanase EC 4.1.99.1
D1115_16440	ENOG4105D9N	nucleoside
D1115_16450	ENOG4105BZU	Histidine kinase
D1115_16470	ENOG4106TD9	Diguanylate cyclase
D1115_16475	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
D1115_16480	ENOG4105EXX	Deoxyribodipyrimidine photolyase-related protein
D1115_16495	ENOG4105E0X	reductase
D1115_16500	ENOG4108UKZ	OsmC family
D1115_16505	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
D1115_16515	ENOG4105PAD	Hydrolase
D1115_16535	ENOG4105EGS	Mechanosensitive ion channel
D1115_16545	ENOG4105UYK	outer membrane protein a
D1115_16560	ENOG4105DUX	Transporter
D1115_16565	ENOG4105EJQ	L-serine dehydratase
D1115_16590	ENOG4105E9H	Lytic Murein transglycosylase
D1115_16610	ENOG4105Q75	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
D1115_16615	ENOG4108ZC9	flagellar basal-body rod protein flgc
D1115_16620	ENOG4105W00	Flagellar hook capping protein
D1115_16625	ENOG4105BZE	flagellar hook protein, FlgE
D1115_16635	ENOG4105CGA	flagellar basal-body rod protein FlgG
D1115_16640	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
D1115_16645	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
D1115_16650	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
D1115_16655	ENOG4105E1Q	flagellar hook-associated protein
D1115_16725	ENOG4105ER2	Ompa motb domain protein
D1115_16730	ENOG4107RD7	Flagellar Motor Protein, MotA
D1115_16760	ENOG4105MQ3	flagellar protein FliS
D1115_16765	ENOG410804A	Flagellar hook-associated 2 domain-containing protein
D1115_16780	ENOG4105I03	Flagellin
D1115_16795	ENOG4105D00	flagellar biosynthetic protein flhB
D1115_16800	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
D1115_16805	ENOG4105VS8	Flagellar biosynthetic protein fliq
D1115_16810	ENOG4105CN7	Flagellar biosynthetic protein FliP
D1115_16815	ENOG4105DD5	Flagellar motor switch protein
D1115_16830	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
D1115_16835	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
D1115_16840	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
D1115_16845	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
D1115_16855	ENOG4108JIR	Flagellum-specific ATP synthase
D1115_16870	ENOG4107SSZ	Phosphatase
D1115_16880	ENOG4105EXG	Transcriptional regulator
D1115_16925	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
D1115_16930	ENOG4105CPQ	Dehydrogenase
D1115_16935	ENOG4107R08	Integrase
D1115_17010	ENOG4105MVE	transcriptional regulator
D1115_17015	ENOG4105ZXK	Dehydrogenase
D1115_17020	ENOG4105G63	Type III effector Hrp-dependent
D1115_17025	ENOG4105FB2	class II Aldolase
D1115_17030	ENOG4105QG4	Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity)
D1115_17035	ENOG4105C6Z	Gluconate
D1115_17045	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
D1115_17050	ENOG4105KT5	UmuD protein
D1115_17055	ENOG4105RWS	endonuclease I
D1115_17090	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
D1115_17115	ENOG4105CPQ	Dehydrogenase
D1115_17120	ENOG4108MA4	Peptidase M66
D1115_17130	ENOG4105D64	Mechanosensitive ion channel
D1115_17140	ENOG4105DMF	Dehydrogenase
D1115_17145	ENOG4105CC0	LysR family Transcriptional regulator
D1115_17155	ENOG4105DAN	ATP-dependent protease
D1115_17165	ENOG4105YE1	PilZ domain
D1115_17175	ENOG4108BGM	Quinol dehydrogenase periplasmic component
D1115_17180	ENOG4105GXZ	Ferredoxin-type protein NapH
D1115_17185	ENOG4105KBH	arsR family transcriptional regulator
D1115_17205	ENOG4108V7D	UPF0397 protein
D1115_17210	ENOG4105EFX	secretion protein, HlyD family
D1115_17215	ENOG4105KK7	inner membrane protein YiaW
D1115_17240	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
D1115_17245	ENOG4107SEY	Conserved Protein
D1115_17255	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
D1115_17260	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
D1115_17270	ENOG4105C1J	atp-dependent rna helicase
D1115_17275	ENOG4107S17	Phosphate-binding protein
D1115_17280	ENOG4105C8U	phosphate abc transporter
D1115_17285	ENOG4105E2Z	phosphate ABC transporter (Permease
D1115_17290	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
D1115_17295	ENOG4105BZU	Histidine kinase
D1115_17325	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
D1115_17330	ENOG41069D7	Methyl-accepting chemotaxis
D1115_17345	ENOG4108UW5	maltose o-acetyltransferase
D1115_17350	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
D1115_17370	ENOG4105KCK	Peptidoglycan-associated lipoprotein
D1115_17380	ENOG4105CK1	PTS System
D1115_17385	ENOG4105CK1	PTS System
D1115_17405	ENOG4105CEP	NADH dehydrogenase
D1115_17410	ENOG4105CK2	sodium dicarboxylate symporter
D1115_17415	ENOG4105MN5	HAD-superfamily hydrolase subfamily IA variant 3
D1115_17420	ENOG4105HHQ	6-phosphogluconolactonase (EC 3.1.1.31)
D1115_17425	ENOG4108V1U	phospholipid-binding protein
D1115_17435	ENOG4105D6J	arsenicaL-resistance protein
D1115_17445	ENOG4105E0U	tyrosine-specific transport protein
D1115_17455	ENOG4105DWD	nucleoside recognition domain protein
D1115_17480	ENOG4105DR5	peptidase
D1115_17490	ENOG4105VW4	glutaredoxin 3
D1115_17495	ENOG4108SXK	Transporter Drug Metabolite Exporter family
D1115_17510	ENOG4105FBJ	fumarylacetoacetate (faa) hydrolase
D1115_17515	ENOG4108UVJ	appr-1-p processing domain protein
D1115_17520	ENOG4105CCF	Lysine exporter protein (Lyse ygga)
D1115_17540	ENOG4105FT1	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I (By similarity)
D1115_17565	ENOG4107TQK	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group (By similarity)
D1115_17570	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
D1115_17575	ENOG4105UYK	outer membrane protein a
D1115_17585	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
D1115_17615	ENOG4105KHC	sulfurtransferase
D1115_17640	ENOG4105D06	uba thif-type nad fad binding protein
D1115_17645	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
D1115_17650	ENOG4105EUJ	GTP cyclohydrolase i
D1115_17655	ENOG4105C5A	transporter
D1115_17680	ENOG4107RGM	aldo keto reductase
D1115_17685	ENOG4108UNF	response regulator
D1115_17695	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
D1115_17700	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
D1115_17705	ENOG4108Z7F	N-acetyltransferase
D1115_17720	ENOG4105Y49	secretion protein, HlyD family
D1115_17730	ENOG4105CD3	dihydroorotase
D1115_17735	ENOG4105DY8	decarboxylase
D1115_17745	ENOG4108MHR	Repressor involved in choline regulation of the bet genes (By similarity)
D1115_17750	ENOG4105C26	Dehydrogenase
D1115_17755	ENOG4105CZ6	Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine (By similarity)
D1115_17765	ENOG4108HQS	Glycine betaine
D1115_17770	ENOG4108IJ7	Glycine betaine
D1115_17775	ENOG4108RCM	Nitroreductase
D1115_17795	ENOG4105BZU	Histidine kinase
D1115_17910	ENOG4105D7W	serine acetyltransferase
D1115_17935	ENOG4105D75	Capsular exopolysaccharide family
D1115_17990	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
D1115_18005	ENOG4105EDR	glucose galactose transporter
D1115_18015	ENOG4108RVA	ribokinase
D1115_18030	ENOG4108Z6Z	Transcriptional regulator
D1115_18055	ENOG4105EM2	membrane
D1115_18065	ENOG4108Z5K	methylglyoxal synthase
D1115_18070	ENOG4108SV3	Tmao reductase system periplasmic protein tort
D1115_18075	ENOG4105BZU	Histidine kinase
D1115_18090	ENOG4105ENH	Sulfatase
D1115_18095	ENOG4105ENH	Sulfatase
D1115_18100	ENOG4108PPB	Seems to be required for the assembly of the photosystem I complex (By similarity)
D1115_18105	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
D1115_18135	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
D1115_18140	ENOG41064T2	transcriptional regulator, lysR family
D1115_18145	ENOG4108YDI	single-species biofilm formation on inanimate substrate
D1115_18165	ENOG4105C4X	radical SAM domain protein
D1115_18175	ENOG4105F2V	VRR-NUC domain-containing protein
D1115_18190	ENOG4105CEE	C4-dicarboxylate transporter
D1115_18210	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
D1115_18275	ENOG4108TVJ	Nitroreductase
D1115_18280	ENOG4107R88	Chemotaxis protein (CheV)
D1115_18300	ENOG4105FR1	rard protein
D1115_18315	ENOG4106CKV	Pap2 superfamily protein
D1115_18320	ENOG4105KPY	Small multidrug resistance protein
D1115_18325	ENOG4108I0N	Transporter, RarD family, DMT superfamily protein
D1115_18335	ENOG4107RGH	Aldehyde dehydrogenase
D1115_18345	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
D1115_18350	ENOG4108UYE	Lactoylglutathione lyase
D1115_18360	ENOG4107RFY	SbcCD D subunit
D1115_18365	ENOG4105EYH	Exonuclease
D1115_18375	ENOG4105E03	chitinase
D1115_18395	ENOG4105QNF	Outer membrane lipoprotein
D1115_18420	ENOG4105DYS	nad(p)h dehydrogenase (quinone)
D1115_18475	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
D1115_18480	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
D1115_18485	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
D1115_18525	ENOG4105DM4	PTS System
D1115_18530	ENOG4105DE4	1-phosphofructokinase
D1115_18535	ENOG4105DTZ	bifunctional PTS system fructose-specific transporter subunit IIA HPr protein
D1115_18540	ENOG4107B7Y	DNA-binding transcriptional regulator FruR
D1115_18555	ENOG4105DRP	amino acid AbC transporter
D1115_18560	ENOG4106TNF	Periplasmic binding protein
D1115_18565	ENOG4105E5Q	amino acid AbC transporter
D1115_18570	ENOG4105CDA	abc transporter atp-binding protein
D1115_18575	ENOG4108I6A	alcohol dehydrogenase
D1115_18580	ENOG4105CF7	AraC family transcriptional regulator
D1115_18590	ENOG4105CKU	formyltetrahydrofolate synthetase
D1115_18595	ENOG4107RE1	Inosine-guanosine kinase
D1115_18625	ENOG4108ZYK	Acyl carrier protein phosphodiesterase
D1115_18630	ENOG4105C1J	atp-dependent rna helicase
D1115_18645	ENOG4105DS1	cytochrome b561
D1115_18655	ENOG4105TMB	Formate nitrite transporter
D1115_18660	ENOG4105DUM	transcriptional regulator, lysR family
D1115_18665	ENOG4108UQ5	membrane protein YcdZ
D1115_18670	ENOG4105CPB	ATP-dependent endonuclease of the OLD family
D1115_18675	ENOG4105CGH	5'-nucleotidase
D1115_18680	ENOG4105DU1	integral membrane protein, terc
D1115_18700	ENOG4108M0H	Extracellular lipase
D1115_18705	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
D1115_18720	ENOG4105KA0	thioesterase Superfamily protein
D1115_18730	ENOG4105KNR	Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity)
D1115_18755	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
D1115_18770	ENOG4105RKW	reductase (By
D1115_18785	ENOG4105CV6	ABC transporter, permease
D1115_18800	ENOG4105P4J	Allophanate hydrolase, subunit 1
D1115_18805	ENOG4105E7W	lamb ycsf family protein
D1115_18810	ENOG4105BZU	Histidine kinase
D1115_18815	ENOG4105CMR	udp-glucose 4-epimerase
D1115_18830	ENOG4105CWB	LysR family transcriptional Regulator
D1115_18835	ENOG4105CD5	CoA-binding domain protein
D1115_18845	ENOG4105CPF	Cell wall formation (By similarity)
D1115_18855	ENOG4108ZJT	translation initiation factor, Sui1
D1115_18890	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
D1115_18895	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
D1115_18910	ENOG4105BZU	Histidine kinase
D1115_18930	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
D1115_18935	ENOG4105E0C	molybdate abc transporter
D1115_18940	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
D1115_18945	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
D1115_18950	ENOG4105WXI	Bacterial OB fold (BOF) protein
D1115_18965	ENOG4105CGF	Aromatic amino acid aminotransferase
D1115_18970	ENOG4105ECQ	AraC Family Transcriptional Regulator
D1115_18975	ENOG4107QI1	Mate efflux family protein
D1115_18980	ENOG4108RDD	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity)
D1115_18985	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
D1115_19060	ENOG4105IPI	Membrane
D1115_19070	ENOG4105EFX	secretion protein, HlyD family
D1115_19085	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
D1115_19090	ENOG4105K63	Thioredoxin
D1115_19095	ENOG4108ISG	Major Facilitator
D1115_19100	ENOG4105VXR	cytoplasmic protein
D1115_19105	ENOG4105KNA	-acetyltransferase
D1115_19125	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
D1115_19130	ENOG4105TMB	Formate nitrite transporter
D1115_19135	ENOG4105WZK	nitrite reductase NADPH small subunit
D1115_19140	ENOG4107QZF	nitrite reductase NADPH large subunit
D1115_19145	ENOG4105BZU	Histidine kinase
D1115_19195	ENOG4105CXG	d-lactate dehydrogenase
D1115_19205	ENOG4105EV2	VWA domain protein interacting with AAA ATPase
D1115_19210	ENOG4107R4Q	Functions as an ATPase. May play a role in metal insertion (metal-chelatase) or as a chaperone (By similarity)
D1115_19220	ENOG4105C5W	Aldolase
D1115_19230	ENOG4105CSX	c4-dicarboxylate anaerobic carrier
D1115_19285	ENOG4105F9F	transposase
D1115_19340	ENOG4105BZ1	(ABC) transporter
D1115_19375	ENOG4105CEY	Amp-dependent synthetase and ligase
D1115_19385	ENOG4105D05	Receptor
D1115_19395	ENOG4105BZU	Histidine kinase
D1115_19410	ENOG4105IPI	Membrane
D1115_19450	ENOG4107QZF	nitrite reductase NADPH large subunit
D1115_19455	ENOG4105D7T	ABC transporter
D1115_19460	ENOG4105DG7	nitrate ABC transporter
D1115_19490	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
D1115_19505	ENOG4105C44	Serine transporter
D1115_19530	ENOG4105G6Z	alkaline phosphatase
D1115_19535	ENOG4105GR3	Histidine kinase
D1115_19540	ENOG4105ETX	regulatoR
D1115_19560	ENOG4105R8A	Heat shock protein
D1115_19575	ENOG4107RUY	(E1 component), alpha subunit
D1115_19580	ENOG4105CPP	Dehydrogenase, E1 component
D1115_19585	ENOG4107QSN	dihydrolipoamide acetyltransferase
D1115_19590	ENOG4105C10	Electron transfer flavoprotein
D1115_19595	ENOG4105BZJ	Electron transfer flavoprotein
D1115_19600	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
D1115_19610	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
D1115_19615	ENOG4107MKT	Stringent starvation protein a
D1115_19620	ENOG4105DUM	transcriptional regulator, lysR family
D1115_19635	ENOG4105DMR	ABC, transporter
D1115_19640	ENOG4105GBT	ABC transporter
D1115_19645	ENOG4106PMH	Extracellular solute-binding protein family 3
D1115_19650	ENOG4105E5Z	arginine transporter ATP-binding subunit
D1115_19665	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
D1115_19675	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
D1115_19680	ENOG4105E39	Enoyl-CoA hydratase
D1115_19685	ENOG4105E39	Enoyl-CoA hydratase
D1115_19690	ENOG4105C1G	acyl-Coa dehydrogenase
D1115_19705	ENOG4105C1G	acyl-Coa dehydrogenase
D1115_19710	ENOG4107QX3	carboxylase
D1115_19715	ENOG41060WC	Enoyl-CoA hydratase
D1115_19720	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
D1115_19735	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
D1115_19825	ENOG4105C3U	ABC transporter
D1115_19830	ENOG4108JMM	(ABC) transporter
D1115_19845	ENOG4105NXH	GreA GreB family elongation factor
D1115_19870	ENOG4107S17	Phosphate-binding protein
D1115_19915	ENOG4105BZU	Histidine kinase
D1115_19920	ENOG4105C7N	Xanthine uracil vitamin C permease
D1115_19925	ENOG4105DKW	ABC transporter
D1115_19945	ENOG4105C1J	atp-dependent rna helicase
D1115_19965	ENOG4108KN7	Removes 5-oxoproline from various penultimate amino acid residues except L-proline (By similarity)
D1115_19985	ENOG4105G4C	Periplasmic ligand-binding sensor protein
D1115_20000	ENOG4105VRT	cytoplasmic protein
D1115_20025	ENOG41090A4	Pterin carbinolamine dehydratase
D1115_20030	ENOG4105MIR	Phenylalanine 4-monooxygenase
D1115_20035	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
D1115_20040	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
D1115_20045	ENOG4108MP6	LysR family Transcriptional regulator
D1115_20060	ENOG4108556	Isoprenoid biosynthesis protein with amidotransferase-like domain
D1115_20065	ENOG4105C0A	alcohol dehydrogenase
D1115_20080	ENOG4108RMU	ferritin dps family protein
D1115_20090	ENOG4108N3W	hemolysin secretion protein
D1115_20100	ENOG4107R39	(ABC) transporter
D1115_20105	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
D1115_20120	ENOG4105VEQ	Cold shock protein
D1115_20150	ENOG4108V1T	peptidylprolyl cis-trans isomerase
D1115_20175	ENOG4105WH1	Two component transcriptional regulator luxr family
D1115_20180	ENOG4107VXZ	Hydrolase
D1115_20185	ENOG4108YZN	class I peptide chain release factor
D1115_20190	ENOG4108N3W	hemolysin secretion protein
D1115_20205	ENOG4107YWA	deoxycytidylate deaminase
D1115_20210	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
D1115_20225	ENOG4105WH1	Two component transcriptional regulator luxr family
D1115_20230	ENOG4105BZU	Histidine kinase
D1115_20245	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
D1115_20255	ENOG4105CUW	cytochrome C-TYPE protein
D1115_20265	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
D1115_20275	ENOG4105CHU	acetyl-coa acetyltransferase
D1115_20285	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
D1115_20290	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
D1115_20325	ENOG4105BZU	Histidine kinase
D1115_20335	ENOG41082IR	Excinuclease ABC C subunit domain protein
D1115_20340	ENOG4108YXG	UPF0502 protein
D1115_20350	ENOG41090HJ	UPF0265 protein
D1115_20380	ENOG4105DQS	Transcriptional regulator
D1115_20415	ENOG4105EFX	secretion protein, HlyD family
D1115_20420	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
D1115_20425	ENOG4105CJW	magnesium transporter
D1115_20430	ENOG4105DQW	permease for cytosine purines, uracil, thiamine, allantoin
D1115_20435	ENOG4105DZC	cytosine deaminase
D1115_20450	ENOG4105EST	Metal Dependent Phosphohydrolase
D1115_20460	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
D1115_20475	ENOG4108Z33	Thiol disulfide Interchange Protein
D1115_20490	ENOG4105EMU	Dehydrogenase
D1115_20495	ENOG4107EXC	regulatoR
D1115_20500	ENOG4105JJR	Histidine kinase
D1115_20510	ENOG4105DIJ	Phosphoethanolamine transferase
D1115_20540	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
D1115_20545	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
D1115_20555	ENOG4105EJC	lysr family transcriptional regulator
D1115_20585	ENOG4105KQ5	peptidylprolyl cis-trans isomerase
D1115_20590	ENOG4105BZU	Histidine kinase
D1115_20600	ENOG4105PYN	Pyridoxamine 5-phosphate oxidase-related
D1115_20610	ENOG4105D4P	Coproporphyrinogen iii oxidase
D1115_20620	ENOG41090AP	transport protein
D1115_20625	ENOG4106GFD	transport protein
D1115_20635	ENOG4105EHG	Permease protein
D1115_20640	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
D1115_20680	ENOG41073TP	transcriptional regulator
D1115_20695	ENOG4107RA1	nh(3)-dependent nad( ) synthetase
D1115_20700	ENOG4105QVC	MOSC domain-containing protein
D1115_20700	ENOG4105QVC	MOSC domain-containing protein
D1115_20715	ENOG4105EKE	dihydroorotase
D1115_20720	ENOG4105CKW	Inner membrane protein yedI
D1115_20735	ENOG4105CIS	alcohol dehydrogenase
D1115_20800	ENOG4106S48	Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division
D1115_20845	ENOG4105EG2	ABC transporter, permease
D1115_20850	ENOG4105D56	permease protein
D1115_20855	ENOG4107FKK	extracellular solute-binding protein family 1
D1115_20865	ENOG4108IJ9	(ABC) transporter
D1115_20870	ENOG4105V0I	UPF0267 protein
D1115_20875	ENOG4108WUH	Transcriptional regulator, TetR family
D1115_20880	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
D1115_20890	ENOG4105CH6	catalase
D1115_20895	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
D1115_20910	ENOG4105DM4	PTS System
D1115_20915	ENOG4108YRF	PTS System
D1115_20925	ENOG4106R3P	AraC family transcriptional regulator
D1115_20930	ENOG4105DM4	PTS System
D1115_20935	ENOG4105EIP	mannose-6-phosphate isomerase
D1115_20940	ENOG4105CT4	transporter
D1115_20950	ENOG4108I5U	Uridine phosphorylase
D1115_20960	ENOG4105D9N	nucleoside
D1115_20965	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
D1115_20975	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
D1115_20990	ENOG4108IEG	Formate dehydrogenase Alpha subunit
D1115_21010	ENOG4108IJF	Heavy metal efflux pump, CzcA
D1115_21040	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
D1115_21050	ENOG4105M6F	mutator MutT protein
D1115_21065	ENOG4108M6U	Universal stress protein A
D1115_21070	ENOG4105MDZ	Transcriptional activator rfaH
D1115_21105	ENOG4108NRW	Phospholipase, patatin family
D1115_21110	ENOG4105EUB	pirin domain protein
D1115_21115	ENOG4105VEQ	Cold shock protein
D1115_21130	ENOG4105EHV	domain protein
D1115_21140	ENOG4105DZ1	carboxypeptidase
D1115_21145	ENOG4105C94	Transporter
D1115_21150	ENOG4105CYM	Glutathione S-transferase
D1115_21160	ENOG4105NAE	bifunctional deaminase-reductase domain protein
D1115_21165	ENOG4105CHR	reductase
D1115_21180	ENOG4105EWI	Short-chain dehydrogenase reductase Sdr
D1115_21190	ENOG4105EJC	lysr family transcriptional regulator
D1115_21195	ENOG410874W	AraC family transcriptional regulator
D1115_21200	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
D1115_21225	ENOG4105C1J	atp-dependent rna helicase
D1115_21245	ENOG4108M6U	Universal stress protein A
D1115_21250	ENOG4105IUQ	nucleoprotein polynucleotide-associated enzyme
D1115_21265	ENOG4105DUM	transcriptional regulator, lysR family
D1115_21270	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
D1115_21275	ENOG4105D3W	isochorismatase
D1115_21280	ENOG4108V1U	phospholipid-binding protein
D1115_21290	ENOG4105CFG	Acts as a chaperone (By similarity)
D1115_21300	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
D1115_21305	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
D1115_21315	ENOG4107KGK	dmso reductase anchor subunit
D1115_21320	ENOG4105QAX	Iron-sulfur
D1115_21325	ENOG4107QY8	reductase
D1115_21330	ENOG4108NEM	leader-binding protein dmsD
D1115_21340	ENOG4108UDW	Transcriptional regulator, luxr family
D1115_21345	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
D1115_21360	ENOG4105D6U	Sodium Glutamate Symporter
D1115_21415	ENOG4107RZC	phospholipase d
D1115_21450	ENOG4108TU9	TRANSCRIPTIONal
D1115_21460	ENOG4108M3R	transcriptional activator CadC
D1115_21470	ENOG4108Z4X	TRANSCRIPTIONal
D1115_21480	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
D1115_21500	ENOG4105VYW	UPF0251 protein
D1115_21510	ENOG4108HQS	Glycine betaine
D1115_21515	ENOG4108IJ7	Glycine betaine
D1115_21520	ENOG4107EII	Lipoprotein involved with copper homeostasis and adhesion
D1115_21525	ENOG4105ETT	transcriptional Regulator, LysR family
D1115_21545	ENOG4105RA2	Membrane
D1115_21555	ENOG4107RH7	Nicotinate phosphoribosyltransferase
D1115_21570	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
D1115_21585	ENOG4105KHA	Glyoxalase Bleomycin resistance protein (Dioxygenase
D1115_21590	ENOG4108F19	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
D1115_21600	ENOG4105DM4	PTS System
D1115_21605	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
D1115_21610	ENOG4105HEI	LysR family (Transcriptional regulator
D1115_21630	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
D1115_21635	ENOG4105C5H	ABC transporter
D1115_21670	ENOG4105IPI	Membrane
D1115_21675	ENOG41068P6	UPF0319 protein
D1115_21685	ENOG4105DP0	ferredoxin-NADP reductase
D1115_21700	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
D1115_21705	ENOG4105EJC	lysr family transcriptional regulator
D1115_21715	ENOG4105DQS	Transcriptional regulator
D1115_21725	ENOG4107YM4	Beta-lactamase domain-containing protein
D1115_21740	ENOG4105DZ1	carboxypeptidase
D1115_21765	ENOG4108M1A	Chitin-binding protein
D1115_21780	ENOG4105C8Q	Methyl-accepting chemotaxis
D1115_21785	ENOG4108NRW	Phospholipase, patatin family
D1115_21790	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
D1115_21795	ENOG4107SFS	Catalyzes the formation of 5-methyl-uridine at position 747 (m5U747) in 23S rRNA (By similarity)
D1115_21810	ENOG4105N0V	mono-oxygenase ydhR
D1115_21840	ENOG4105CK2	sodium dicarboxylate symporter
D1115_21850	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
D1115_21855	ENOG4108P2H	Inner membrane protein YjiG
D1115_21860	ENOG41074DU	domain protein
D1115_21865	ENOG4107T9C	Alpha amylase catalytic region
D1115_21870	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
D1115_21875	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
D1115_21880	ENOG4107RTM	4-alpha-glucanotransferase (EC 2.4.1.25)
D1115_21885	ENOG4107QQN	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
D1115_21925	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
D1115_21930	ENOG4107QV7	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) (By similarity)
D1115_21935	ENOG4107XGF	functions in a salvage pathway. Uses pyridoxamine (By similarity)
D1115_21945	ENOG4105D5Q	Arginine ornithine antiporter
D1115_21950	ENOG4105CXN	decarboxylase
D1115_21970	ENOG4108IUK	alpha amylase, catalytic
D1115_21985	ENOG4108KDD	Involved in the transport of maltose and maltodextrins (By similarity)
D1115_21995	ENOG4105BZU	Histidine kinase
D1115_22015	ENOG4105D05	Receptor
D1115_22030	ENOG4105DHS	permease protein
D1115_22035	ENOG4105CM4	permease protein
D1115_22040	ENOG4108IPW	abc transporter atp-binding protein
D1115_22045	ENOG41062JF	Transcriptional regulator
D1115_22095	ENOG4105CFP	Peptidase U32
D1115_22110	ENOG4105C19	ABC transporter
D1115_22140	ENOG4105D3R	alkyl hydroperoxide reductase
D1115_22145	ENOG4108JU3	Alkyl hydroperoxide reductase
D1115_22150	ENOG4105VEQ	Cold shock protein
D1115_22155	ENOG4105C8Y	Acetylornithine aminotransferase
D1115_22160	ENOG4108RYR	transcriptional regulator AsnC family
D1115_22165	ENOG4105ENR	peptidase, M24
D1115_22190	ENOG4105ECQ	AraC Family Transcriptional Regulator
D1115_22195	ENOG4105CIR	epoxide hydrolase
D1115_22200	ENOG4105CIR	epoxide hydrolase
D1115_22205	ENOG4105C1J	atp-dependent rna helicase
D1115_22220	ENOG4105EJC	lysr family transcriptional regulator
D1115_22225	ENOG4105CHZ	Catalyzes the dehydration of D-mannonate (By similarity)
D1115_22230	ENOG4105DEI	Mannitol dehydrogenase
D1115_22240	ENOG4107SS6	2-dehydro-3-deoxygluconokinase
D1115_22245	ENOG4108UHU	Aldolase
D1115_22260	ENOG4105CT4	transporter
D1115_22265	ENOG4105CNT	hydrolase family 2
D1115_22275	ENOG4105C6F	GntR Family Transcriptional Regulator
D1115_22280	ENOG4108QNI	outer membrane porin protein
D1115_22305	ENOG4105EW9	transcriptional regulator AsnC family
D1115_22330	ENOG4105CK7	Sodium proline symporter
D1115_22340	ENOG4105C26	Dehydrogenase
D1115_22355	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
D1115_22360	ENOG4105CQZ	Histidine kinase
D1115_22365	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
D1115_22370	ENOG4107QZV	Type I secretion membrane fusion protein
D1115_22410	ENOG4105E0I	Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) (By similarity)
D1115_22415	ENOG4106RMF	ParB family
D1115_22435	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
D1115_22440	ENOG4105DF3	Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta-cleavage pathway for the degradation of aromatic compounds (By similarity)
D1115_22445	ENOG4105DIV	Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD( ) and coenzyme A. Is the final enzyme in the meta- cleavage pathway for the degradation of aromatic compounds (By similarity)
D1115_22460	ENOG4105D25	secreted protein
D1115_22555	ENOG4108UYB	regulatoR
D1115_22565	ENOG4105C8S	subunit m
D1115_22595	ENOG4105KJM	monovalent cation h antiporter subunit g
D1115_22625	ENOG4107RCV	ABC transporter, permease
D1115_22630	ENOG4108K85	Transcriptional regulator
D1115_22675	ENOG4108IPT	Naphthoate synthase
D1115_22685	ENOG4106YT9	Enoyl-CoA hydratase
D1115_22690	ENOG4105CC9	acyl-Coa dehydrogenase
D1115_22695	ENOG4105D2B	acyl-CoA dehydrogenase
D1115_22700	ENOG4105F2C	Acetyl-CoA acetyltransferase
D1115_22705	ENOG4105KF3	Short-chain dehydrogenase reductase Sdr
D1115_22720	ENOG4105KRQ	Addiction module toxin, Txe YoeB family
D1115_22725	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
D1115_22760	ENOG4108KC1	acyl-Coa dehydrogenase
D1115_22775	ENOG4105BZJ	Electron transfer flavoprotein
D1115_22780	ENOG4105C10	Electron transfer flavoprotein
D1115_22795	ENOG4105CHR	reductase
D1115_22820	ENOG4105X7H	acyl-CoA dehydrogenase
D1115_22825	ENOG4105CC9	acyl-Coa dehydrogenase
D1115_22850	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
D1115_22855	ENOG4105C11	sulfate adenylyltransferase), subunit 2
D1115_22860	ENOG4105P12	pyruvate phosphate dikinase
D1115_22865	ENOG4108Z86	Glutamine amidotransferase
D1115_22880	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
D1115_22895	ENOG4108NMT	An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon (By similarity)
D1115_22900	ENOG4108KMV	Glycosyl transferase (Group 1
D1115_22905	ENOG4107QPH	glycogen) synthase
D1115_22910	ENOG4105CAQ	asparagine synthetase
D1115_22985	ENOG4105PE8	Translocates 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane (By similarity)
D1115_23020	ENOG4108KMV	Glycosyl transferase (Group 1
D1115_23035	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
D1115_23050	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
D1115_23155	ENOG4105IYK	transposase
D1115_23160	ENOG4105DQ6	Transposase
D1115_23165	ENOG4105DQ6	Transposase
D1115_23175	ENOG4105BZU	Histidine kinase
D1115_23180	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
D1115_23190	ENOG4105CHU	acetyl-coa acetyltransferase
D1115_23205	ENOG4108UNC	
D1115_23220	ENOG4105CHR	reductase
D1115_23225	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
D1115_23230	ENOG4105CHR	reductase
D1115_23235	ENOG4105CEY	Amp-dependent synthetase and ligase
D1115_23240	ENOG4105DAB	fumarate reductase succinate dehydrogenase flavoprotein domain protein
D1115_23255	ENOG4105C6X	Major Facilitator