locus-tag	class	description
Vag1382_00010	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
Vag1382_00020	COG0592	DNA-directed DNA polymerase activity
Vag1382_00040	COG0187	DNA topoisomerase II activity
Vag1382_00070	COG0071	Belongs to the small heat shock protein (HSP20) family
Vag1382_00080	COG3977	Valine--pyruvate aminotransferase
Vag1382_00090	COG0366	Alpha amylase catalytic
Vag1382_00100	COG0751	glycine-tRNA ligase activity
Vag1382_00120	COG2119	membrane
Vag1382_00140	COG0425	Belongs to the sulfur carrier protein TusA family
Vag1382_00170	COG0604	alcohol dehydrogenase
Vag1382_00180	COG0183	Belongs to the thiolase family
Vag1382_00200	COG1739	Uncharacterized protein family UPF0029
Vag1382_00210	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
Vag1382_00230	COG0583	DNA-binding transcription factor activity
Vag1382_00240	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
Vag1382_00250	COG2960	long-chain fatty acid transporting porin activity
Vag1382_00260	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Vag1382_00270	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Vag1382_00330	COG4166	transmembrane transport
Vag1382_00350	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Vag1382_00420	COG1609	Transcriptional regulator
Vag1382_00430	COG0583	DNA-binding transcription factor activity
Vag1382_00460	COG0129	dihydroxy-acid dehydratase activity
Vag1382_00470	COG3265	gluconokinase activity
Vag1382_00480	COG2610	gluconate transmembrane transporter activity
Vag1382_00490	COG0800	Aldolase
Vag1382_00500	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
Vag1382_00510	COG0583	DNA-binding transcription factor activity
Vag1382_00520	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Vag1382_00530	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
Vag1382_00550	COG1522	sequence-specific DNA binding
Vag1382_00560	COG5001	Diguanylate cyclase
Vag1382_00560	COG5002	protein histidine kinase activity
Vag1382_00570	COG0742	ribosomal rna small subunit methyltransferase
Vag1382_00600	COG0589	response to stress
Vag1382_00610	COG1528	Iron-storage protein
Vag1382_00630	COG2081	HI0933 family
Vag1382_00640	COG2204	response regulator
Vag1382_00690	COG1597	lipid kinase activity
Vag1382_00750	COG0628	permease
Vag1382_00780	COG1322	Protein conserved in bacteria
Vag1382_00790	COG2226	methyltransferase
Vag1382_00800	COG3165	ubiquinone biosynthetic process from chorismate
Vag1382_00810	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
Vag1382_00830	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
Vag1382_00840	COG0805	protein transport
Vag1382_00850	COG0084	hydrolase, TatD family'
Vag1382_00870	COG0456	acetyltransferase
Vag1382_00880	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Vag1382_00880	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Vag1382_00890	COG0218	Necessary for normal cell division and for the maintenance of normal septation
Vag1382_00950	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
Vag1382_00970	COG2204	response regulator
Vag1382_00980	COG3852	Histidine kinase
Vag1382_01000	COG0174	glutamine synthetase
Vag1382_01040	COG1295	ribonuclease BN
Vag1382_01050	COG1490	D-aminoacyl-tRNA deacylase activity
Vag1382_01060	COG0456	acetyltransferase
Vag1382_01080	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
Vag1382_01090	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
Vag1382_01100	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
Vag1382_01110	COG3031	protein transport across the cell outer membrane
Vag1382_01130	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
Vag1382_01140	COG1459	type II secretion system
Vag1382_01150	COG2165	general secretion pathway protein
Vag1382_01160	COG2165	general secretion pathway protein
Vag1382_01170	COG2165	general secretion pathway protein
Vag1382_01180	COG4795	General secretion pathway protein
Vag1382_01190	COG3156	type II secretion system protein K
Vag1382_01200	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
Vag1382_01210	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
Vag1382_01230	COG1218	3'(2'),5'-bisphosphate nucleotidase
Vag1382_01240	COG0494	nUDIX hydrolase
Vag1382_01250	COG0316	Belongs to the HesB IscA family
Vag1382_01250	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
Vag1382_01260	COG1040	competence protein
Vag1382_01270	COG0596	Alpha beta hydrolase
Vag1382_01290	COG2183	response to ionizing radiation
Vag1382_01310	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
Vag1382_01330	COG0745	RESPONSE REGULATOR receiver
Vag1382_01340	COG2205	protein histidine kinase activity
Vag1382_01350	COG2233	PERMEase
Vag1382_01360	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
Vag1382_01370	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
Vag1382_01380	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
Vag1382_01390	COG1758	RNA polymerase activity
Vag1382_01400	COG0194	GDP metabolic process
Vag1382_01430	COG0848	biopolymer transport protein
Vag1382_01440	COG0811	peptide transport
Vag1382_01480	COG4174	ABC transporter (Permease)
Vag1382_01490	COG4239	(ABC) transporter, permease
Vag1382_01500	COG0747	negative chemotaxis
Vag1382_01510	COG0444	Belongs to the ABC transporter superfamily
Vag1382_01520	COG4608	Belongs to the ABC transporter superfamily
Vag1382_01540	COG1561	YicC-like family, N-terminal region
Vag1382_01550	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
Vag1382_01570	COG1560	Kdo2-lipid A biosynthetic process
Vag1382_01580	COG1309	transcriptional regulator
Vag1382_01590	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
Vag1382_01610	COG2003	Belongs to the UPF0758 family
Vag1382_01700	COG0463	Glycosyl transferase, family 2
Vag1382_01710	COG0859	PFAM glycosyl transferase family 9
Vag1382_01720	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
Vag1382_01730	COG3642	lipopolysaccharide core region biosynthetic process
Vag1382_01770	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
Vag1382_01790	COG1086	Polysaccharide biosynthesis protein
Vag1382_01800	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
Vag1382_01810	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
Vag1382_01820	COG2089	acid synthase
Vag1382_01840	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
Vag1382_01850	COG1083	cytidylyl-transferase
Vag1382_01870	COG1519	Transferase
Vag1382_01880	COG0859	PFAM glycosyl transferase family 9
Vag1382_01890	COG1560	Kdo2-lipid A biosynthetic process
Vag1382_01910	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
Vag1382_02070	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
Vag1382_02080	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
Vag1382_02090	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
Vag1382_02140	COG1045	serine acetyltransferase
Vag1382_02170	COG0438	transferase activity, transferring glycosyl groups
Vag1382_02180	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
Vag1382_02200	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
Vag1382_02240	COG0149	triose-phosphate isomerase activity
Vag1382_02290	COG1494	fructose-1,6-bisphosphatase
Vag1382_02310	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
Vag1382_02320	COG1575	Belongs to the MenA family. Type 1 subfamily
Vag1382_02330	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
Vag1382_02340	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
Vag1382_02370	COG1609	Transcriptional regulator
Vag1382_02380	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
Vag1382_02390	COG0254	rRNA binding
Vag1382_02410	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
Vag1382_02420	COG0088	Forms part of the polypeptide exit tunnel
Vag1382_02440	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
Vag1382_02450	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
Vag1382_02460	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
Vag1382_02470	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
Vag1382_02490	COG0255	Belongs to the universal ribosomal protein uL29 family
Vag1382_02500	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
Vag1382_02520	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
Vag1382_02530	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
Vag1382_02540	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
Vag1382_02550	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
Vag1382_02560	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
Vag1382_02590	COG1841	ribosomal large subunit assembly
Vag1382_02610	COG0201	protein transport
Vag1382_02620	COG0257	Belongs to the bacterial ribosomal protein bL36 family
Vag1382_02630	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
Vag1382_02640	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
Vag1382_02660	COG0202	RNA polymerase activity
Vag1382_02670	COG0203	ribosomal protein L17
Vag1382_02690	COG0545	Peptidyl-prolyl cis-trans isomerase
Vag1382_02710	COG2153	protein acetylation
Vag1382_02720	COG0513	Belongs to the DEAD box helicase family
Vag1382_02740	COG0737	Belongs to the 5'-nucleotidase family
Vag1382_02750	COG1648	precorrin-2 dehydrogenase activity
Vag1382_02750	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
Vag1382_02760	COG0175	sulfate reduction
Vag1382_02770	COG2895	sulfate adenylyltransferase (ATP) activity
Vag1382_02780	COG0471	metal ion transport
Vag1382_02780	COG3273	potassium ion transport
Vag1382_02790	COG0529	Catalyzes the synthesis of activated sulfate
Vag1382_02840	COG4181	ATPase activity
Vag1382_02870	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
Vag1382_02890	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Vag1382_02900	COG0729	surface antigen
Vag1382_02910	COG2911	Protein conserved in bacteria
Vag1382_02920	COG2105	PFAM AIG2 family protein
Vag1382_02940	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
Vag1382_02950	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
Vag1382_02960	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
Vag1382_02970	COG0163	prenyltransferase activity
Vag1382_02980	COG4143	(ABC) transporter
Vag1382_02990	COG1178	ABC-type Fe3 transport system permease component
Vag1382_03000	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
Vag1382_03010	COG0583	DNA-binding transcription factor activity
Vag1382_03020	COG1902	pentaerythritol trinitrate reductase activity
Vag1382_03050	COG2358	TRAP transporter, solute receptor (TAXI family
Vag1382_03090	COG0142	geranyltranstransferase activity
Vag1382_03100	COG0261	This protein binds to 23S rRNA in the presence of protein L20
Vag1382_03120	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
Vag1382_03130	COG2966	Psort location CytoplasmicMembrane, score
Vag1382_03160	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
Vag1382_03170	COG2967	ApaG domain
Vag1382_03180	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
Vag1382_03190	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
Vag1382_03200	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
Vag1382_03210	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
Vag1382_03220	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
Vag1382_03260	COG0473	3-isopropylmalate dehydrogenase activity
Vag1382_03270	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Vag1382_03310	COG0583	DNA-binding transcription factor activity
Vag1382_03320	COG1022	Amp-dependent synthetase and ligase
Vag1382_03330	COG0028	Belongs to the TPP enzyme family
Vag1382_03350	COG3706	GGDEF domain
Vag1382_03370	COG0469	pyruvate kinase activity
Vag1382_03380	COG1349	DNA-binding transcription factor activity
Vag1382_03390	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
Vag1382_03420	COG5002	protein histidine kinase activity
Vag1382_03440	COG2376	Dihydroxyacetone kinase
Vag1382_03450	COG1461	Dihydroxyacetone kinase
Vag1382_03480	COG3722	fumarate hydratase activity
Vag1382_03490	COG0246	Mannitol dehydrogenase
Vag1382_03500	COG2213	PTS system mannitol-specific
Vag1382_03500	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
Vag1382_03560	COG1464	Belongs to the NlpA lipoprotein family
Vag1382_03580	COG0358	DNA primase activity
Vag1382_03590	COG1610	YqeY-like protein
Vag1382_03600	COG0828	Belongs to the bacterial ribosomal protein bS21 family
Vag1382_03610	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
Vag1382_03620	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
Vag1382_03630	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
Vag1382_03640	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
Vag1382_03650	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
Vag1382_03660	COG1968	undecaprenyl-diphosphatase activity
Vag1382_03670	COG0617	tRNA 3'-terminal CCA addition
Vag1382_03680	COG3409	Peptidoglycan-binding domain 1 protein
Vag1382_03680	COG3267	Type II secretory pathway component ExeA
Vag1382_03700	COG0405	Gamma-glutamyltransferase
Vag1382_03710	COG4991	sh3 domain protein
Vag1382_03720	COG0306	phosphate transporter
Vag1382_03730	COG1392	Phosphate transport regulator
Vag1382_03740	COG3025	triphosphatase activity
Vag1382_03770	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
Vag1382_03780	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
Vag1382_03780	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
Vag1382_03790	COG1538	Outer membrane efflux protein
Vag1382_03800	COG0494	nUDIX hydrolase
Vag1382_03810	COG3151	Protein conserved in bacteria
Vag1382_03830	COG3150	esterase
Vag1382_03850	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
Vag1382_03860	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Vag1382_03880	COG3105	Protein conserved in bacteria
Vag1382_03890	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
Vag1382_03900	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
Vag1382_03910	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
Vag1382_03920	COG0723	plastoquinol--plastocyanin reductase activity
Vag1382_03930	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
Vag1382_03940	COG2857	Cytochrome c1
Vag1382_03950	COG0625	glutathione transferase activity
Vag1382_03960	COG2969	positive regulation of protein catabolic process
Vag1382_03970	COG2823	Periplasmic or secreted lipoprotein
Vag1382_03980	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
Vag1382_04010	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
Vag1382_04030	COG3116	cell division
Vag1382_04040	COG0768	penicillin binding
Vag1382_04050	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
Vag1382_04060	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
Vag1382_04070	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
Vag1382_04080	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
Vag1382_04090	COG0772	Belongs to the SEDS family
Vag1382_04110	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
Vag1382_04120	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
Vag1382_04130	COG0849	cell division
Vag1382_04140	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
Vag1382_04150	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
Vag1382_04170	COG0653	protein targeting
Vag1382_04180	COG0494	nUDIX hydrolase
Vag1382_04210	COG0505	Belongs to the CarA family
Vag1382_04220	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
Vag1382_04250	COG0730	response to heat
Vag1382_04260	COG0583	DNA-binding transcription factor activity
Vag1382_04270	COG2860	membrane
Vag1382_04320	COG0493	'glutamate synthase
Vag1382_04330	COG0069	glutamate synthase activity
Vag1382_04330	COG0070	glutamate synthase
Vag1382_04330	COG0067	glutamate synthase
Vag1382_04350	COG0067	glutamate synthase
Vag1382_04350	COG0069	glutamate synthase activity
Vag1382_04350	COG0070	glutamate synthase
Vag1382_04360	COG1242	4 iron, 4 sulfur cluster binding
Vag1382_04370	COG5001	Diguanylate cyclase
Vag1382_04370	COG4251	negative regulation of phosphorylation
Vag1382_04370	COG3706	GGDEF domain
Vag1382_04370	COG2203	Gaf domain
Vag1382_04380	COG0784	Response regulator, receiver
Vag1382_04380	COG5002	protein histidine kinase activity
Vag1382_04380	COG2198	Histidine kinase
Vag1382_04400	COG0745	RESPONSE REGULATOR receiver
Vag1382_04420	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
Vag1382_04450	COG0083	homoserine kinase activity
Vag1382_04460	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
Vag1382_04480	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
Vag1382_04490	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
Vag1382_04500	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
Vag1382_04530	COG1115	amino acid carrier protein
Vag1382_04540	COG3022	response to hydroperoxide
Vag1382_04550	COG0513	Belongs to the DEAD box helicase family
Vag1382_04560	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
Vag1382_04580	COG0716	FMN binding
Vag1382_04590	COG4974	Belongs to the 'phage' integrase family
Vag1382_04600	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
Vag1382_04610	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
Vag1382_04620	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
Vag1382_04630	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
Vag1382_04640	COG2204	response regulator
Vag1382_04670	COG0667	Aldo Keto reductase
Vag1382_04720	COG0730	response to heat
Vag1382_04740	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
Vag1382_04760	COG1283	sodium-dependent phosphate transmembrane transporter activity
Vag1382_04770	COG0583	DNA-binding transcription factor activity
Vag1382_04780	COG0640	Transcriptional regulator
Vag1382_04790	COG0268	Binds directly to 16S ribosomal RNA
Vag1382_04800	COG0728	peptidoglycan biosynthetic process
Vag1382_04810	COG0196	riboflavin kinase activity
Vag1382_04830	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
Vag1382_04840	COG1047	Peptidyl-prolyl cis-trans
Vag1382_04850	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
Vag1382_04890	COG3279	Response regulator of the LytR AlgR family
Vag1382_04900	COG3275	phosphorelay sensor kinase activity
Vag1382_04910	COG1966	Carbon starvation protein
Vag1382_04950	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
Vag1382_04960	COG1472	Belongs to the glycosyl hydrolase 3 family
Vag1382_04970	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
Vag1382_04980	COG1605	Chorismate mutase
Vag1382_04980	COG0287	Prephenate dehydrogenase
Vag1382_04990	COG0739	heme binding
Vag1382_04990	COG0741	lytic transglycosylase activity
Vag1382_04990	COG1196	nuclear chromosome segregation
Vag1382_05010	COG0488	(ABC) transporter
Vag1382_05030	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
Vag1382_05040	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
Vag1382_05050	COG0077	Prephenate dehydratase
Vag1382_05050	COG1605	Chorismate mutase
Vag1382_05060	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
Vag1382_05070	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
Vag1382_05080	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
Vag1382_05090	COG0564	pseudouridine synthase activity
Vag1382_05110	COG0542	response to heat
Vag1382_05150	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
Vag1382_05170	COG2974	May be involved in recombination
Vag1382_05180	COG0745	RESPONSE REGULATOR receiver
Vag1382_05190	COG5002	protein histidine kinase activity
Vag1382_05210	COG0248	Ppx GppA phosphatase
Vag1382_05220	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
Vag1382_05230	COG0573	inorganic phosphate transmembrane transporter activity
Vag1382_05240	COG0581	inorganic phosphate transmembrane transporter activity
Vag1382_05250	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
Vag1382_05260	COG0704	Plays a role in the regulation of phosphate uptake
Vag1382_05280	COG3142	Participates in the control of copper homeostasis
Vag1382_05290	COG0450	alkyl hydroperoxide reductase
Vag1382_05300	COG0583	DNA-binding transcription factor activity
Vag1382_05310	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
Vag1382_05330	COG0517	IMP dehydrogenase activity
Vag1382_05350	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
Vag1382_05370	COG1862	Preprotein translocase
Vag1382_05380	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
Vag1382_05390	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
Vag1382_05400	COG0483	inositol monophosphate 1-phosphatase activity
Vag1382_05410	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
Vag1382_05430	COG1104	cysteine desulfurase activity
Vag1382_05440	COG0822	iron-sulfur transferase activity
Vag1382_05470	COG0443	Heat shock 70 kDa protein
Vag1382_05480	COG0633	Ferredoxin
Vag1382_05490	COG2975	iron-sulfur cluster assembly
Vag1382_05510	COG0105	UTP biosynthetic process
Vag1382_05540	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
Vag1382_05550	COG0124	histidyl-tRNA synthetase
Vag1382_05560	COG2976	Protein conserved in bacteria
Vag1382_05570	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
Vag1382_05580	COG1160	GTP binding
Vag1382_05620	COG0516	GMP reductase activity
Vag1382_05620	COG0517	IMP dehydrogenase activity
Vag1382_05630	COG0519	Catalyzes the synthesis of GMP from XMP
Vag1382_05630	COG0518	GMP synthase (glutamine-hydrolyzing) activity
Vag1382_05640	COG0582	viral genome integration into host DNA
Vag1382_05800	COG1757	Na H antiporter
Vag1382_05820	COG1584	GPR1 FUN34 yaaH family protein
Vag1382_05830	COG1115	amino acid carrier protein
Vag1382_05870	COG2873	o-acetylhomoserine
Vag1382_05880	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
Vag1382_05920	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
Vag1382_05920	COG3153	acetyltransferase
Vag1382_05930	COG0583	DNA-binding transcription factor activity
Vag1382_05950	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
Vag1382_05960	COG2867	negative regulation of translational initiation
Vag1382_05970	COG2914	Belongs to the UPF0125 (RnfH) family
Vag1382_05980	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
Vag1382_05990	COG0497	DNA recombination
Vag1382_06010	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
Vag1382_06020	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
Vag1382_06030	COG1301	dicarboxylic acid transport
Vag1382_06050	COG0484	heat shock protein binding
Vag1382_06110	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
Vag1382_06130	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
Vag1382_06140	COG0047	phosphoribosylformylglycinamidine synthase activity
Vag1382_06140	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
Vag1382_06170	COG1629	transport
Vag1382_06200	COG2195	Cleaves the N-terminal amino acid of tripeptides
Vag1382_06210	COG2252	PERMEase
Vag1382_06220	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
Vag1382_06260	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
Vag1382_06270	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
Vag1382_06280	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
Vag1382_06290	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
Vag1382_06290	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
Vag1382_06320	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
Vag1382_06340	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
Vag1382_06350	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
Vag1382_06360	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
Vag1382_06370	COG0142	geranyltranstransferase activity
Vag1382_06380	COG1722	exodeoxyribonuclease VII activity
Vag1382_06390	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
Vag1382_06410	COG0301	tRNA thio-modification
Vag1382_06410	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
Vag1382_06430	COG0583	DNA-binding transcription factor activity
Vag1382_06450	COG2363	Small membrane protein
Vag1382_06470	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Vag1382_06480	COG1611	Belongs to the LOG family
Vag1382_06510	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
Vag1382_06510	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
Vag1382_06530	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
Vag1382_06540	COG1464	Belongs to the NlpA lipoprotein family
Vag1382_06550	COG2011	ABC-type metal ion transport system permease component
Vag1382_06560	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
Vag1382_06570	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
Vag1382_06590	COG1263	PTS System
Vag1382_06590	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
Vag1382_06600	COG0366	Alpha amylase catalytic
Vag1382_06640	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
Vag1382_06650	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
Vag1382_06660	COG0321	lipoyl(octanoyl) transferase activity
Vag1382_06680	COG1686	Belongs to the peptidase S11 family
Vag1382_06690	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
Vag1382_06700	COG0772	Belongs to the SEDS family
Vag1382_06710	COG0768	penicillin binding
Vag1382_06720	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
Vag1382_06730	COG0799	negative regulation of ribosome biogenesis
Vag1382_06740	COG1466	dna polymerase III delta subunit
Vag1382_06750	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
Vag1382_06760	COG0495	leucyl-tRNA aminoacylation
Vag1382_06770	COG2888	peptidyl-tyrosine sulfation
Vag1382_06780	COG0815	Transfers the fatty acyl group on membrane lipoproteins
Vag1382_06790	COG4535	Mg2 and Co2 transporter CorC
Vag1382_06800	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
Vag1382_06810	COG1702	phosphate starvation-inducible protein PhoH
Vag1382_06820	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
Vag1382_06830	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Vag1382_06840	COG0012	GTP binding
Vag1382_06850	COG0193	aminoacyl-tRNA hydrolase activity
Vag1382_06860	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
Vag1382_06870	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
Vag1382_06880	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
Vag1382_06890	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
Vag1382_06910	COG2890	protein-(glutamine-N5) methyltransferase activity
Vag1382_06920	COG3094	Invasion gene expression up-regulator, SirB
Vag1382_06930	COG2912	Transglutaminase-like superfamily
Vag1382_06940	COG2877	3-deoxy-8-phosphooctulonate synthase activity
Vag1382_06950	COG0737	Belongs to the 5'-nucleotidase family
Vag1382_06970	COG1187	pseudouridine synthase activity
Vag1382_06980	COG2840	Smr protein MutS2
Vag1382_07050	COG2217	Heavy metal translocating P-type atpase
Vag1382_07050	COG2608	mercury ion transmembrane transporter activity
Vag1382_07070	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
Vag1382_07170	COG0784	Response regulator, receiver
Vag1382_07170	COG0835	chemotaxis
Vag1382_07180	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
Vag1382_07190	COG1815	bacterial-type flagellum-dependent cell motility
Vag1382_07200	COG1558	bacterial-type flagellum-dependent cell motility
Vag1382_07220	COG1749	Flagellar hook protein flgE
Vag1382_07230	COG4787	bacterial-type flagellum-dependent cell motility
Vag1382_07250	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
Vag1382_07260	COG1706	bacterial-type flagellum-dependent cell motility
Vag1382_07270	COG3951	Flagellar rod assembly protein muramidase FlgJ
Vag1382_07270	COG1705	Flagellar rod assembly protein muramidase FlgJ
Vag1382_07290	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
Vag1382_07310	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
Vag1382_07320	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
Vag1382_07330	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
Vag1382_07340	COG2190	(PTS) system
Vag1382_07350	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
Vag1382_07370	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
Vag1382_07380	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
Vag1382_07390	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
Vag1382_07400	COG3115	cell septum assembly
Vag1382_07410	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
Vag1382_07460	COG0330	HflC and HflK could
Vag1382_07470	COG3118	belongs to the thioredoxin family
Vag1382_07480	COG0300	oxidoreductase activity
Vag1382_07490	COG1090	epimerase
Vag1382_07550	COG0622	Phosphoesterase
Vag1382_07590	COG3710	Transcriptional regulator
Vag1382_07600	COG0326	Molecular chaperone. Has ATPase activity
Vag1382_07620	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
Vag1382_07640	COG3104	oligopeptide transport
Vag1382_07650	COG0250	Participates in transcription elongation, termination and antitermination
Vag1382_07660	COG0367	asparagine synthase
Vag1382_07670	COG4651	solute:proton antiporter activity
Vag1382_07670	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
Vag1382_07680	COG1846	Transcriptional regulator
Vag1382_07680	COG1940	carbohydrate kinase activity
Vag1382_07690	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
Vag1382_07700	COG2190	(PTS) system
Vag1382_07700	COG1263	PTS System
Vag1382_07700	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
Vag1382_07710	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
Vag1382_07720	COG0735	belongs to the Fur family
Vag1382_07740	COG0716	FMN binding
Vag1382_07760	COG0596	Alpha beta hydrolase
Vag1382_07770	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
Vag1382_07780	COG0033	Phosphoglucomutase
Vag1382_07800	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
Vag1382_07830	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
Vag1382_07840	COG1053	succinate dehydrogenase
Vag1382_07850	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
Vag1382_07860	COG0567	Dehydrogenase, E1 component
Vag1382_07870	COG0508	dehydrogenase complex catalyzes the overall conversion of
Vag1382_07900	COG1108	ABC-type Mn2 Zn2 transport systems permease components
Vag1382_07910	COG1121	(ABC) transporter
Vag1382_07920	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
Vag1382_07930	COG4977	sequence-specific DNA binding
Vag1382_07940	COG1918	ferrous iron import across plasma membrane
Vag1382_07980	COG0018	arginyl-trna synthetase
Vag1382_07990	COG3102	Protein conserved in bacteria
Vag1382_08020	COG0788	formyltetrahydrofolate deformylase activity
Vag1382_08030	COG1199	ATP-dependent helicase activity
Vag1382_08040	COG1214	PFAM Peptidase M22, glycoprotease
Vag1382_08060	COG3065	identical protein binding
Vag1382_08070	COG2267	carboxylic ester hydrolase activity
Vag1382_08080	COG0318	PFAM AMP-dependent synthetase and ligase
Vag1382_08090	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
Vag1382_08100	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
Vag1382_08110	COG2894	cell division
Vag1382_08120	COG0850	regulation of cytokinetic process
Vag1382_08130	COG3100	YcgL domain-containing protein
Vag1382_08140	COG2951	lytic endotransglycosylase activity
Vag1382_08160	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
Vag1382_08170	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
Vag1382_08180	COG2226	methyltransferase
Vag1382_08190	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
Vag1382_08200	COG1028	Short-chain dehydrogenase reductase Sdr
Vag1382_08220	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
Vag1382_08270	COG2986	histidine ammonia-lyase
Vag1382_08280	COG1216	Glycosyl transferase, family 2
Vag1382_08290	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
Vag1382_08320	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
Vag1382_08330	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
Vag1382_08400	COG1253	flavin adenine dinucleotide binding
Vag1382_08410	COG0513	Belongs to the DEAD box helicase family
Vag1382_08420	COG0569	domain protein
Vag1382_08430	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
Vag1382_08460	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
Vag1382_08470	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
Vag1382_08480	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
Vag1382_08490	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
Vag1382_08520	COG0544	peptidyl-prolyl cis-trans isomerase activity
Vag1382_08540	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
Vag1382_08550	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
Vag1382_08560	COG0776	regulation of translation
Vag1382_08570	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
Vag1382_08580	COG1555	photosystem II stabilization
Vag1382_08610	COG0232	Belongs to the dGTPase family. Type 2 subfamily
Vag1382_08620	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
Vag1382_08630	COG0436	Aminotransferase
Vag1382_08640	COG1169	isochorismate synthase
Vag1382_08650	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
Vag1382_08660	COG0596	Alpha beta hydrolase
Vag1382_08670	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
Vag1382_08710	COG2855	membrane
Vag1382_08720	COG0477	Major facilitator Superfamily
Vag1382_08750	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Vag1382_08760	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Vag1382_08800	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
Vag1382_08810	COG1522	sequence-specific DNA binding
Vag1382_08830	COG1946	Acyl-CoA thioesterase
Vag1382_08840	COG3126	Type III secretion system lipoprotein chaperone (YscW)
Vag1382_08980	COG0583	DNA-binding transcription factor activity
Vag1382_08990	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
Vag1382_09000	COG2207	Transcriptional regulator
Vag1382_09010	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
Vag1382_09020	COG0516	GMP reductase activity
Vag1382_09020	COG0517	IMP dehydrogenase activity
Vag1382_09070	COG0537	adenosine 5'-monophosphoramidase activity
Vag1382_09120	COG3150	esterase
Vag1382_09130	COG1252	NADH dehydrogenase
Vag1382_09160	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
Vag1382_09180	COG4591	ABC-type transport system involved in lipoprotein release permease component
Vag1382_09190	COG1136	(ABC) transporter
Vag1382_09200	COG4591	ABC-type transport system involved in lipoprotein release permease component
Vag1382_09220	COG2333	competence protein COMEC
Vag1382_09220	COG0658	competence protein
Vag1382_09230	COG1132	(ABC) transporter
Vag1382_09240	COG1663	tetraacyldisaccharide 4'-kinase activity
Vag1382_09270	COG2719	SpoVR family
Vag1382_09280	COG2718	Belongs to the UPF0229 family
Vag1382_09290	COG2766	serine protein kinase
Vag1382_09300	COG3013	Belongs to the UPF0304 family
Vag1382_09320	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
Vag1382_09340	COG1882	Formate acetyltransferase
Vag1382_09420	COG0708	Exodeoxyribonuclease III
Vag1382_09440	COG3923	Primosomal replication protein n
Vag1382_09450	COG0730	response to heat
Vag1382_09460	COG1199	ATP-dependent helicase activity
Vag1382_09470	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
Vag1382_09480	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
Vag1382_09490	COG1187	pseudouridine synthase activity
Vag1382_09510	COG1278	Cold shock
Vag1382_09520	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
Vag1382_09530	COG0542	response to heat
Vag1382_09540	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
Vag1382_09550	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
Vag1382_09560	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
Vag1382_09600	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
Vag1382_09610	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
Vag1382_09620	COG0297	glycogen (starch) synthase activity
Vag1382_09660	COG3070	regulator of competence-specific genes
Vag1382_09670	COG1609	Transcriptional regulator
Vag1382_09680	COG3381	protein complex oligomerization
Vag1382_09690	COG0745	RESPONSE REGULATOR receiver
Vag1382_09700	COG1434	Gram-negative-bacterium-type cell wall biogenesis
Vag1382_09710	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
Vag1382_09730	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
Vag1382_09740	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
Vag1382_09780	COG0189	ligase activity
Vag1382_09780	COG4067	protein conserved in archaea
Vag1382_09790	COG0500	methyltransferase
Vag1382_09810	COG1801	Protein of unknown function DUF72
Vag1382_09830	COG0217	transcriptional regulatory protein
Vag1382_09840	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
Vag1382_09850	COG0632	four-way junction helicase activity
Vag1382_09860	COG2255	four-way junction helicase activity
Vag1382_09870	COG1271	oxidase subunit
Vag1382_09880	COG1294	oxidase, subunit
Vag1382_09890	COG4890	Cyd operon protein YbgT
Vag1382_09910	COG0824	Thioesterase
Vag1382_09920	COG0811	peptide transport
Vag1382_09950	COG0823	Involved in the tonB-independent uptake of proteins
Vag1382_09960	COG2885	chlorophyll binding
Vag1382_09970	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
Vag1382_09980	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
Vag1382_10000	COG3766	membrane
Vag1382_10020	COG0754	glutathionylspermidine amidase activity
Vag1382_10040	COG0784	Response regulator, receiver
Vag1382_10040	COG5002	protein histidine kinase activity
Vag1382_10060	COG0840	transmembrane signaling receptor activity
Vag1382_10070	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Vag1382_10080	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Vag1382_10130	COG3568	Endonuclease Exonuclease Phosphatase
Vag1382_10150	COG0840	transmembrane signaling receptor activity
Vag1382_10180	COG0583	DNA-binding transcription factor activity
Vag1382_10200	COG0686	Belongs to the AlaDH PNT family
Vag1382_10220	COG1674	ftsk spoiiie
Vag1382_10230	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
Vag1382_10240	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
Vag1382_10250	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
Vag1382_10310	COG1073	alpha beta
Vag1382_10310	COG2226	methyltransferase
Vag1382_10320	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
Vag1382_10370	COG0300	oxidoreductase activity
Vag1382_10400	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
Vag1382_10420	COG2268	Band 7 protein
Vag1382_10440	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
Vag1382_10450	COG2915	High frequency lysogenization protein hflD homolog
Vag1382_10460	COG0482	sulfurtransferase activity
Vag1382_10480	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Vag1382_10500	COG1757	Na H antiporter
Vag1382_10520	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
Vag1382_10530	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
Vag1382_10540	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
Vag1382_10550	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
Vag1382_10550	COG0131	Imidazoleglycerol-phosphate dehydratase
Vag1382_10560	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
Vag1382_10570	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
Vag1382_10590	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
Vag1382_10590	COG0140	phosphoribosyl-ATP diphosphatase activity
Vag1382_10670	COG3850	Histidine kinase
Vag1382_10670	COG5002	protein histidine kinase activity
Vag1382_10680	COG0745	RESPONSE REGULATOR receiver
Vag1382_10690	COG0840	transmembrane signaling receptor activity
Vag1382_10720	COG1032	radical SAM domain protein
Vag1382_10730	COG5001	Diguanylate cyclase
Vag1382_10760	COG0583	DNA-binding transcription factor activity
Vag1382_10770	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
Vag1382_10790	COG2350	Protein conserved in bacteria
Vag1382_10810	COG2917	probably involved in intracellular septation
Vag1382_10850	COG1301	dicarboxylic acid transport
Vag1382_10860	COG0318	PFAM AMP-dependent synthetase and ligase
Vag1382_10870	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Vag1382_10880	COG0159	tryptophan synthase activity
Vag1382_10900	COG0134	indole-3-glycerol-phosphate synthase activity
Vag1382_10900	COG0135	phosphoribosylanthranilate isomerase activity
Vag1382_10920	COG0512	Glutamine amidotransferase of anthranilate synthase
Vag1382_10930	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
Vag1382_10950	COG0613	PHP domain protein
Vag1382_10960	COG0009	L-threonylcarbamoyladenylate synthase
Vag1382_10990	COG1187	pseudouridine synthase activity
Vag1382_11030	COG0417	DNA replication proofreading
Vag1382_11040	COG2197	response regulator
Vag1382_11050	COG0322	excinuclease ABC activity
Vag1382_11090	COG0019	diaminopimelate decarboxylase activity
Vag1382_11150	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
Vag1382_11160	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
Vag1382_11210	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
Vag1382_11230	COG0437	4 iron, 4 sulfur cluster binding
Vag1382_11240	COG3301	Polysulphide reductase, NrfD
Vag1382_11250	COG1138	Cytochrome C-type biogenesis protein
Vag1382_11270	COG3088	subunit of a heme lyase
Vag1382_11270	COG4235	cytochrome complex assembly
Vag1382_11290	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
Vag1382_11340	COG2989	Protein conserved in bacteria
Vag1382_11350	COG3108	Peptidase M15
Vag1382_11360	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Vag1382_11390	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
Vag1382_11450	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
Vag1382_11460	COG0840	transmembrane signaling receptor activity
Vag1382_11500	COG1448	Aminotransferase
Vag1382_11530	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Vag1382_11550	COG0017	Asparaginyl-tRNA synthetase
Vag1382_11560	COG0840	transmembrane signaling receptor activity
Vag1382_11580	COG0720	synthase
Vag1382_11600	COG2200	EAL domain
Vag1382_11610	COG1760	l-serine dehydratase
Vag1382_11620	COG0814	amino acid
Vag1382_11630	COG0494	nUDIX hydrolase
Vag1382_11650	COG0784	Response regulator, receiver
Vag1382_11650	COG2205	protein histidine kinase activity
Vag1382_11660	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
Vag1382_11690	COG3106	COG3106 Predicted ATPase
Vag1382_11700	COG3768	UPF0283 membrane protein
Vag1382_11720	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Vag1382_12170	COG0729	surface antigen
Vag1382_12180	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
Vag1382_12190	COG2272	Belongs to the type-B carboxylesterase lipase family
Vag1382_12260	COG2985	domain, Protein
Vag1382_12280	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
Vag1382_12310	COG0583	DNA-binding transcription factor activity
Vag1382_12370	COG0210	DNA helicase
Vag1382_12400	COG4735	regulation of single-species biofilm formation
Vag1382_12470	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
Vag1382_12480	COG2944	sequence-specific DNA binding
Vag1382_12550	COG1566	PFAM secretion protein HlyD family protein
Vag1382_12580	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Vag1382_12610	COG3290	protein histidine kinase activity
Vag1382_12620	COG4565	transcriptional regulatory protein
Vag1382_12630	COG4774	siderophore transport
Vag1382_12650	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
Vag1382_12660	COG0363	glucosamine-6-phosphate deaminase activity
Vag1382_12670	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
Vag1382_12700	COG3284	Transcriptional regulator
Vag1382_12710	COG1012	belongs to the aldehyde dehydrogenase family
Vag1382_12850	COG4669	(LipO)protein
Vag1382_12890	COG3177	Filamentation induced by cAMP protein fic
Vag1382_12950	COG1028	Short-chain dehydrogenase reductase Sdr
Vag1382_13000	COG4792	protein secretion
Vag1382_13010	COG4791	protein targeting
Vag1382_13020	COG4794	Type iii secretion
Vag1382_13030	COG4790	Type iii secretion
Vag1382_13170	COG0457	Tetratricopeptide repeat
Vag1382_13210	COG2358	TRAP transporter, solute receptor (TAXI family
Vag1382_13220	COG0730	response to heat
Vag1382_13290	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
Vag1382_13300	COG0372	Belongs to the citrate synthase family
Vag1382_13320	COG2828	Protein conserved in bacteria
Vag1382_13370	COG0561	phosphatase activity
Vag1382_13380	COG0602	queuosine metabolic process
Vag1382_13390	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
Vag1382_13400	COG3706	GGDEF domain
Vag1382_13500	COG1254	Belongs to the acylphosphatase family
Vag1382_13510	COG2920	part of a sulfur-relay system
Vag1382_13530	COG0670	Belongs to the BI1 family
Vag1382_13540	COG1126	abc transporter atp-binding protein
Vag1382_13550	COG0765	amino acid transport
Vag1382_13560	COG4597	amino acid ABC transporter
Vag1382_13570	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Vag1382_13590	COG1666	GTP binding
Vag1382_13600	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
Vag1382_13650	COG3008	intermembrane lipid transfer
Vag1382_13660	COG2995	paraquat-inducible protein a
Vag1382_13670	COG1132	(ABC) transporter
Vag1382_13680	COG1956	GAF domain-containing protein
Vag1382_13690	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
Vag1382_13720	COG0308	aminopeptidase N
Vag1382_13740	COG2902	Dehydrogenase
Vag1382_13750	COG0167	dihydroorotate dehydrogenase activity
Vag1382_13770	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
Vag1382_13770	COG0116	Belongs to the methyltransferase superfamily
Vag1382_13820	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
Vag1382_13830	COG1067	ATP-dependent peptidase activity
Vag1382_13840	COG3120	sequence-specific DNA binding
Vag1382_14110	COG2205	protein histidine kinase activity
Vag1382_14110	COG0784	Response regulator, receiver
Vag1382_14140	COG3278	Belongs to the heme-copper respiratory oxidase family
Vag1382_14170	COG2010	Cytochrome c
Vag1382_14190	COG2217	Heavy metal translocating P-type atpase
Vag1382_14220	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Vag1382_14230	COG0589	response to stress
Vag1382_14280	COG3842	ATPase activity
Vag1382_14300	COG1177	transmembrane transport
Vag1382_14320	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
Vag1382_14330	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
Vag1382_14350	COG0004	ammonium transporteR
Vag1382_14400	COG0437	4 iron, 4 sulfur cluster binding
Vag1382_14410	COG3383	formate dehydrogenase (NAD+) activity
Vag1382_14410	COG0243	molybdopterin cofactor binding
Vag1382_14430	COG3381	protein complex oligomerization
Vag1382_14470	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
Vag1382_14490	COG0488	(ABC) transporter
Vag1382_14500	COG4191	Histidine kinase
Vag1382_14510	COG2204	response regulator
Vag1382_14540	COG3842	ATPase activity
Vag1382_14550	COG0746	molybdenum cofactor guanylyltransferase activity
Vag1382_14580	COG1940	carbohydrate kinase activity
Vag1382_14650	COG0791	NLP P60 protein
Vag1382_14670	COG3706	GGDEF domain
Vag1382_14690	COG3001	Fructosamine kinase
Vag1382_14710	COG0307	riboflavin synthase, alpha
Vag1382_14720	COG0534	Mate efflux family protein
Vag1382_14740	COG1793	dna ligase
Vag1382_14800	COG2204	response regulator
Vag1382_14820	COG0438	transferase activity, transferring glycosyl groups
Vag1382_14880	COG0438	transferase activity, transferring glycosyl groups
Vag1382_14890	COG1215	transferase activity, transferring glycosyl groups
Vag1382_14900	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
Vag1382_14920	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
Vag1382_14950	COG1643	Atp-dependent helicase
Vag1382_14960	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
Vag1382_15050	COG0443	Heat shock 70 kDa protein
Vag1382_15060	COG0443	Heat shock 70 kDa protein
Vag1382_15100	COG4968	Prepilin-type N-terminal cleavage methylation domain
Vag1382_15110	COG1132	(ABC) transporter
Vag1382_15120	COG1132	(ABC) transporter
Vag1382_15140	COG4774	siderophore transport
Vag1382_15150	COG4774	siderophore transport
Vag1382_15170	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
Vag1382_15180	COG1120	ATPase activity
Vag1382_15210	COG0814	amino acid
Vag1382_15230	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
Vag1382_15250	COG0861	Integral membrane protein TerC family
Vag1382_15270	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
Vag1382_15280	COG1328	CTP reductase activity
Vag1382_15310	COG3300	MHYT domain
Vag1382_15310	COG5001	Diguanylate cyclase
Vag1382_15330	COG4191	Histidine kinase
Vag1382_15340	COG0471	metal ion transport
Vag1382_15390	COG4702	Belongs to the UPF0303 family
Vag1382_15400	COG0673	inositol 2-dehydrogenase activity
Vag1382_15440	COG0641	radical SAM
Vag1382_15480	COG3119	arylsulfatase activity
Vag1382_15490	COG0527	aspartate kinase activity
Vag1382_15500	COG0662	Cupin 2, conserved barrel domain protein
Vag1382_15510	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
Vag1382_15520	COG0456	acetyltransferase
Vag1382_15530	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
Vag1382_15570	COG4176	ABC-type proline glycine betaine transport system permease component
Vag1382_15580	COG2113	Glycine betaine
Vag1382_15620	COG1028	Short-chain dehydrogenase reductase Sdr
Vag1382_15640	COG0745	RESPONSE REGULATOR receiver
Vag1382_15650	COG0642	Histidine kinase
Vag1382_15660	COG1368	sulfuric ester hydrolase activity
Vag1382_15740	COG1115	amino acid carrier protein
Vag1382_15760	COG1280	lysine exporter protein (LysE YggA)
Vag1382_15770	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
Vag1382_15840	COG1162	GTPase activity
Vag1382_15870	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
Vag1382_15880	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
Vag1382_15890	COG1160	GTP binding
Vag1382_15900	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
Vag1382_15920	COG1160	GTP binding
Vag1382_15990	COG1570	exodeoxyribonuclease VII activity
Vag1382_16080	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
Vag1382_16100	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
Vag1382_16170	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
Vag1382_16180	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
Vag1382_16190	COG1560	Kdo2-lipid A biosynthetic process
Vag1382_16210	COG0531	amino acid
Vag1382_16240	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
Vag1382_16250	COG3063	Type IV pilus biogenesis stability protein PilW
Vag1382_16310	COG0110	maltose O-acetyltransferase activity
Vag1382_16340	COG2315	Protein conserved in bacteria
Vag1382_16350	COG1846	Transcriptional regulator
Vag1382_16370	COG2200	EAL domain
Vag1382_16420	COG0625	glutathione transferase activity
Vag1382_16440	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
Vag1382_16460	COG2195	Cleaves the N-terminal amino acid of tripeptides
Vag1382_16480	COG0601	transmembrane transport
Vag1382_16490	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Vag1382_16530	COG3291	Pkd domain containing protein
Vag1382_16560	COG1177	transmembrane transport
Vag1382_16570	COG1176	ABC-type spermidine putrescine transport system, permease component I
Vag1382_16580	COG3842	ATPase activity
Vag1382_16590	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Vag1382_16600	COG2423	ornithine cyclodeaminase activity
Vag1382_16630	COG3938	Belongs to the proline racemase family
Vag1382_16690	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
Vag1382_16700	COG1451	nucleotide metabolic process
Vag1382_16720	COG0583	DNA-binding transcription factor activity
Vag1382_16760	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
Vag1382_16770	COG4139	cobalamin transport
Vag1382_16780	COG2988	succinylglutamate desuccinylase activity
Vag1382_16820	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
Vag1382_16830	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
Vag1382_16840	COG0702	epimerase
Vag1382_16860	COG2925	Exonuclease
Vag1382_16870	COG1380	Effector of murein hydrolase LrgA
Vag1382_16880	COG1346	cytolysis
Vag1382_16890	COG0295	cytidine deaminase activity
Vag1382_16900	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
Vag1382_16910	COG0500	methyltransferase
Vag1382_16930	COG0776	regulation of translation
Vag1382_16950	COG0072	phenylalanine-tRNA ligase activity
Vag1382_16950	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Vag1382_16960	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
Vag1382_17020	COG0393	Putative heavy-metal-binding
Vag1382_17040	COG0291	Belongs to the bacterial ribosomal protein bL35 family
Vag1382_17060	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
Vag1382_17090	COG2188	Transcriptional regulator
Vag1382_17100	COG1228	amidohydrolase
Vag1382_17110	COG0010	Belongs to the arginase family
Vag1382_17120	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
Vag1382_17130	COG2986	histidine ammonia-lyase
Vag1382_17160	COG0277	FAD linked oxidase domain protein
Vag1382_17160	COG0247	lactate metabolic process
Vag1382_17230	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
Vag1382_17260	COG1643	Atp-dependent helicase
Vag1382_17270	COG0281	malic enzyme
Vag1382_17280	COG2949	membrane
Vag1382_17290	COG0471	metal ion transport
Vag1382_17300	COG0471	metal ion transport
Vag1382_17360	COG0492	ferredoxin-NADP+ reductase activity
Vag1382_17370	COG4988	ABC transporter
Vag1382_17380	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
Vag1382_17400	COG2885	chlorophyll binding
Vag1382_17440	COG3121	Chaperone
Vag1382_17460	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
Vag1382_17480	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Vag1382_17480	COG4191	Histidine kinase
Vag1382_17520	COG3070	regulator of competence-specific genes
Vag1382_17540	COG2431	L-lysine efflux transmembrane transporter activity
Vag1382_17560	COG0076	glutamate decarboxylase activity
Vag1382_17570	COG1737	Transcriptional regulator
Vag1382_17590	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
Vag1382_17600	COG3273	potassium ion transport
Vag1382_17600	COG2985	domain, Protein
Vag1382_17610	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
Vag1382_17620	COG1960	acyl-CoA dehydrogenase activity
Vag1382_17640	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
Vag1382_17680	COG0534	Mate efflux family protein
Vag1382_17690	COG0702	epimerase
Vag1382_17700	COG3005	denitrification pathway
Vag1382_17760	COG2814	Major facilitator Superfamily
Vag1382_17770	COG1187	pseudouridine synthase activity
Vag1382_17780	COG1061	Type III restriction enzyme res subunit
Vag1382_17800	COG0745	RESPONSE REGULATOR receiver
Vag1382_17810	COG2205	protein histidine kinase activity
Vag1382_17820	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
Vag1382_17870	COG4134	Bacterial extracellular solute-binding protein
Vag1382_17880	COG4135	transport system, permease component
Vag1382_17890	COG4136	ATPase activity
Vag1382_17900	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
Vag1382_17920	COG3604	Transcriptional regulator
Vag1382_17930	COG1151	hydroxylamine reductase activity
Vag1382_17940	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
Vag1382_17960	COG0564	pseudouridine synthase activity
Vag1382_17970	COG0733	neurotransmitter:sodium symporter activity
Vag1382_17980	COG0733	neurotransmitter:sodium symporter activity
Vag1382_18000	COG0626	cystathionine gamma-synthase activity
Vag1382_18010	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
Vag1382_18020	COG5380	lipid catabolic process
Vag1382_18030	COG2818	Glycosylase
Vag1382_18070	COG1983	PspC domain protein
Vag1382_18090	COG1842	Phage shock protein A
Vag1382_18100	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
Vag1382_18130	COG4171	peptide transport system, permease
Vag1382_18150	COG4172	Belongs to the ABC transporter superfamily
Vag1382_18170	COG1227	inorganic diphosphatase activity
Vag1382_18200	COG0243	molybdopterin cofactor binding
Vag1382_18210	COG3005	denitrification pathway
Vag1382_18220	COG4459	periplasmic nitrate reductase
Vag1382_18230	COG0390	transport system, permease component
Vag1382_18250	COG2116	formate transmembrane transporter activity
Vag1382_18300	COG1434	Gram-negative-bacterium-type cell wall biogenesis
Vag1382_18310	COG1435	thymidine kinase activity
Vag1382_18320	COG0215	cysteine-tRNA ligase activity
Vag1382_18330	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
Vag1382_18340	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
Vag1382_18350	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
Vag1382_18360	COG3012	SEC-C Motif Domain Protein
Vag1382_18420	COG1136	(ABC) transporter
Vag1382_18420	COG0577	efflux transmembrane transporter activity
Vag1382_18440	COG0577	efflux transmembrane transporter activity
Vag1382_18440	COG1136	(ABC) transporter
Vag1382_18460	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Vag1382_18510	COG3118	belongs to the thioredoxin family
Vag1382_18520	COG4232	protein-disulfide reductase activity
Vag1382_18590	COG2863	cytochrome
Vag1382_18600	COG3258	Cytochrome c
Vag1382_18610	COG2995	paraquat-inducible protein a
Vag1382_18620	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
Vag1382_18620	COG3008	intermembrane lipid transfer
Vag1382_18650	COG4166	transmembrane transport
Vag1382_18670	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
Vag1382_18680	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
Vag1382_18700	COG0539	negative regulation of cytoplasmic translation
Vag1382_18710	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
Vag1382_18720	COG0616	signal peptide processing
Vag1382_18730	COG1028	Short-chain dehydrogenase reductase Sdr
Vag1382_18760	COG0587	DNA-directed DNA polymerase activity
Vag1382_18770	COG0835	chemotaxis
Vag1382_18770	COG0784	Response regulator, receiver
Vag1382_18780	COG1940	carbohydrate kinase activity
Vag1382_18790	COG0469	pyruvate kinase activity
Vag1382_18800	COG4667	esterase of the alpha-beta hydrolase superfamily
Vag1382_18830	COG0733	neurotransmitter:sodium symporter activity
Vag1382_18860	COG1263	PTS System
Vag1382_18860	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
Vag1382_18870	COG0084	hydrolase, TatD family'
Vag1382_18880	COG0470	DNA polymerase III
Vag1382_18890	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
Vag1382_18900	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
Vag1382_18960	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
Vag1382_18970	COG0416	fatty acid biosynthetic process
Vag1382_18990	COG1399	metal-binding, possibly nucleic acid-binding protein
Vag1382_19000	COG0424	maF-like protein
Vag1382_19010	COG0564	pseudouridine synthase activity
Vag1382_19020	COG1530	ribonuclease E activity
Vag1382_19030	COG0659	secondary active sulfate transmembrane transporter activity
Vag1382_19040	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
Vag1382_19050	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
Vag1382_19070	COG0572	uridine kinase
Vag1382_19120	COG2186	Transcriptional regulator
Vag1382_19130	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
Vag1382_19140	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
Vag1382_19150	COG0653	protein targeting
Vag1382_19160	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
Vag1382_19170	COG3706	GGDEF domain
Vag1382_19180	COG0366	Alpha amylase catalytic
Vag1382_19190	COG1122	ATPase activity
Vag1382_19200	COG4120	Belongs to the binding-protein-dependent transport system permease family
Vag1382_19220	COG3092	negative regulation of chromosome organization
Vag1382_19230	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
Vag1382_19240	COG0857	belongs to the CobB CobQ family
Vag1382_19240	COG0280	phosphate acetyltransferase
Vag1382_19250	COG3174	membrane
Vag1382_19270	COG0435	Glutathione S-transferase
Vag1382_19290	COG0444	Belongs to the ABC transporter superfamily
Vag1382_19300	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Vag1382_19310	COG0601	transmembrane transport
Vag1382_19330	COG0314	molybdopterin synthase activity
Vag1382_19340	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
Vag1382_19350	COG0315	cyclic pyranopterin monophosphate synthase activity
Vag1382_19360	COG0521	Mo-molybdopterin cofactor biosynthetic process
Vag1382_19370	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
Vag1382_19380	COG0391	Required for morphogenesis under gluconeogenic growth conditions
Vag1382_19390	COG2198	Histidine kinase
Vag1382_19400	COG2204	response regulator
Vag1382_19410	COG0556	nucleotide-excision repair
Vag1382_19420	COG4657	Part of a membrane complex involved in electron transport
Vag1382_19430	COG2878	Part of a membrane complex involved in electron transport
Vag1382_19440	COG4656	Part of a membrane complex involved in electron transport
Vag1382_19450	COG4658	electron transport chain
Vag1382_19460	COG4659	FMN binding
Vag1382_19470	COG4660	Part of a membrane complex involved in electron transport
Vag1382_19480	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
Vag1382_19490	COG0346	lactoylglutathione lyase activity
Vag1382_19510	COG2885	chlorophyll binding
Vag1382_19530	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
Vag1382_19540	COG2056	Na+-H+ antiporter family
Vag1382_19560	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
Vag1382_19600	COG1012	belongs to the aldehyde dehydrogenase family
Vag1382_19600	COG1454	alcohol dehydrogenase
Vag1382_19610	COG2095	MarC family integral membrane protein
Vag1382_19620	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Vag1382_19630	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
Vag1382_19640	COG1757	Na H antiporter
Vag1382_19670	COG3081	Nucleoid-associated protein
Vag1382_19680	COG3082	Protein of unknown function (DUF1414)
Vag1382_19700	COG0123	including yeast histone deacetylase and acetoin utilization protein
Vag1382_19730	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
Vag1382_19740	COG0778	Nitroreductase
Vag1382_19760	COG0446	pyridine nucleotide-disulphide oxidoreductase
Vag1382_19760	COG1902	pentaerythritol trinitrate reductase activity
Vag1382_19770	COG0616	signal peptide processing
Vag1382_19780	COG0252	asparaginase activity
Vag1382_19790	COG3139	Protein of unknown function (DUF1315)
Vag1382_19810	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Vag1382_19820	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
Vag1382_19850	COG2226	methyltransferase
Vag1382_19880	COG1785	Belongs to the alkaline phosphatase family
Vag1382_19900	COG0346	lactoylglutathione lyase activity
Vag1382_19910	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
Vag1382_19920	COG0668	transmembrane transport
Vag1382_19930	COG2983	Belongs to the UPF0260 family
Vag1382_19940	COG2261	transglycosylase associated protein
Vag1382_19970	COG3681	Belongs to the UPF0597 family
Vag1382_19980	COG0251	oxidation-reduction process
Vag1382_19990	COG0814	amino acid
Vag1382_20000	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
Vag1382_20010	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
Vag1382_20040	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
Vag1382_20050	COG2832	Protein of unknown function (DUF454)
Vag1382_20070	COG0745	RESPONSE REGULATOR receiver
Vag1382_20080	COG0583	DNA-binding transcription factor activity
Vag1382_20090	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
Vag1382_20100	COG1286	toxin biosynthetic process
Vag1382_20110	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
Vag1382_20120	COG0285	dihydrofolate synthase activity
Vag1382_20130	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
Vag1382_20140	COG0101	tRNA pseudouridine synthase activity
Vag1382_20160	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
Vag1382_20170	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Vag1382_20180	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
Vag1382_20190	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
Vag1382_20190	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Vag1382_20200	COG0431	NADPH-dependent FMN reductase
Vag1382_20220	COG3101	peptidyl-lysine hydroxylation
Vag1382_20230	COG2860	membrane
Vag1382_20240	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
Vag1382_20250	COG2890	protein-(glutamine-N5) methyltransferase activity
Vag1382_20260	COG2840	Smr protein MutS2
Vag1382_20270	COG2062	phosphohistidine phosphatase, SixA
Vag1382_20300	COG1024	Enoyl-CoA hydratase
Vag1382_20300	COG1250	3-hydroxyacyl-CoA dehydrogenase
Vag1382_20310	COG0183	Belongs to the thiolase family
Vag1382_20350	COG2067	long-chain fatty acid transport protein
Vag1382_20370	COG4235	cytochrome complex assembly
Vag1382_20370	COG3088	subunit of a heme lyase
Vag1382_20390	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Vag1382_20400	COG1138	Cytochrome C-type biogenesis protein
Vag1382_20410	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
Vag1382_20420	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
Vag1382_20430	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
Vag1382_20440	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
Vag1382_20450	COG4133	protoheme IX ABC transporter activity
Vag1382_20470	COG0835	chemotaxis
Vag1382_20490	COG1192	Involved in chromosome partitioning
Vag1382_20500	COG2201	protein-glutamate methylesterase activity
Vag1382_20510	COG0643	Histidine kinase
Vag1382_20510	COG2198	Histidine kinase
Vag1382_20510	COG0784	Response regulator, receiver
Vag1382_20520	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
Vag1382_20600	COG1987	bacterial-type flagellum assembly
Vag1382_20700	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
Vag1382_20720	COG1677	Flagellar hook-basal body complex protein FliE
Vag1382_20740	COG4191	Histidine kinase
Vag1382_20760	COG1516	flagellar protein fliS
Vag1382_20780	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
Vag1382_20790	COG1334	flagellar protein FlaG
Vag1382_20800	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
Vag1382_20810	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
Vag1382_20820	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
Vag1382_20830	COG2837	iron assimilation
Vag1382_20880	COG1393	Belongs to the ArsC family
Vag1382_20890	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Vag1382_20930	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Vag1382_20950	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
Vag1382_20980	COG4783	chaperone-mediated protein folding
Vag1382_20990	COG1393	Belongs to the ArsC family
Vag1382_21030	COG2233	PERMEase
Vag1382_21040	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
Vag1382_21050	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
Vag1382_21060	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
Vag1382_21070	COG0121	glutamine amidotransferase
Vag1382_21080	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
Vag1382_21090	COG1960	acyl-CoA dehydrogenase activity
Vag1382_21160	COG0328	RNA-DNA hybrid ribonuclease activity
Vag1382_21170	COG2226	methyltransferase
Vag1382_21180	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Vag1382_21190	COG1388	LysM domain
Vag1382_21190	COG0741	lytic transglycosylase activity
Vag1382_21210	COG3021	interspecies interaction between organisms
Vag1382_21220	COG0347	Belongs to the P(II) protein family
Vag1382_21250	COG0825	malonyl-CoA metabolic process
Vag1382_21260	COG0587	DNA-directed DNA polymerase activity
Vag1382_21280	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
Vag1382_21290	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
Vag1382_21310	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
Vag1382_21320	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
Vag1382_21340	COG0750	zinc metalloprotease
Vag1382_21350	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
Vag1382_21360	COG0575	Belongs to the CDS family
Vag1382_21370	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
Vag1382_21380	COG0233	cytoplasmic translational termination
Vag1382_21390	COG0528	UMP kinase activity
Vag1382_21400	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
Vag1382_21410	COG0052	Belongs to the universal ribosomal protein uS2 family
Vag1382_21420	COG0024	Methionine aminopeptidase
Vag1382_21430	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
Vag1382_21450	COG0564	pseudouridine synthase activity
Vag1382_21520	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
Vag1382_21530	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Vag1382_21580	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
Vag1382_21590	COG0254	rRNA binding
Vag1382_21600	COG1720	tRNA m6t6A37 methyltransferase activity
Vag1382_21610	COG0442	prolyl-tRNA aminoacylation
Vag1382_21650	COG0733	neurotransmitter:sodium symporter activity
Vag1382_21680	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
Vag1382_21690	COG0514	ATP-dependent DNA helicase (RecQ)
Vag1382_21700	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
Vag1382_21730	COG1477	protein flavinylation
Vag1382_21740	COG2871	sodium ion transport
Vag1382_21750	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
Vag1382_21760	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
Vag1382_21770	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
Vag1382_21780	COG1805	sodium ion transport
Vag1382_21790	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
Vag1382_21800	COG0271	Belongs to the BolA IbaG family
Vag1382_21810	COG2813	Specifically methylates the guanine in position
Vag1382_21820	COG3056	Lipoprotein
Vag1382_21860	COG1595	DNA-templated transcription, initiation
Vag1382_21900	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
Vag1382_21910	COG0693	protein deglycase activity
Vag1382_21920	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
Vag1382_21930	COG3706	GGDEF domain
Vag1382_21950	COG2166	iron-sulfur cluster assembly
Vag1382_21960	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
Vag1382_21970	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
Vag1382_21990	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
Vag1382_21990	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
Vag1382_22030	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
Vag1382_22040	COG1074	ATP-dependent DNA helicase activity
Vag1382_22050	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
Vag1382_22090	COG3141	response to X-ray
Vag1382_22100	COG2171	N-acyltransferase activity
Vag1382_22110	COG0584	glycerophosphoryl diester phosphodiesterase
Vag1382_22120	COG2271	Major facilitator Superfamily
Vag1382_22130	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
Vag1382_22140	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
Vag1382_22150	COG1349	DNA-binding transcription factor activity
Vag1382_22160	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
Vag1382_22200	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Vag1382_22210	COG1609	Transcriptional regulator
Vag1382_22220	COG2211	Major facilitator Superfamily
Vag1382_22250	COG2017	converts alpha-aldose to the beta-anomer
Vag1382_22260	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
Vag1382_22280	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
Vag1382_22290	COG1609	Transcriptional regulator
Vag1382_22300	COG3250	beta-galactosidase activity
Vag1382_22310	COG2731	YhcH YjgK YiaL family protein
Vag1382_22320	COG0531	amino acid
Vag1382_22330	COG0583	DNA-binding transcription factor activity
Vag1382_22450	COG4964	Belongs to the GSP D family
Vag1382_22500	COG2169	Transcriptional regulator
Vag1382_22510	COG1022	Amp-dependent synthetase and ligase
Vag1382_22530	COG0583	DNA-binding transcription factor activity
Vag1382_22540	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
Vag1382_22550	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
Vag1382_22570	COG0560	Phosphoserine phosphatase
Vag1382_22590	COG0813	purine-nucleoside phosphorylase activity
Vag1382_22600	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
Vag1382_22610	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
Vag1382_22630	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
Vag1382_22640	COG0084	hydrolase, TatD family'
Vag1382_22660	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
Vag1382_22810	COG0191	fructose-bisphosphate aldolase activity
Vag1382_22860	COG0501	Belongs to the peptidase M48B family
Vag1382_22890	COG0542	response to heat
Vag1382_22920	COG0443	Heat shock 70 kDa protein
Vag1382_22930	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
Vag1382_22960	COG0071	Belongs to the small heat shock protein (HSP20) family
Vag1382_22970	COG0071	Belongs to the small heat shock protein (HSP20) family
Vag1382_23090	COG2003	Belongs to the UPF0758 family
Vag1382_23140	COG0714	Associated with various cellular activities
Vag1382_23180	COG0629	single-stranded DNA binding
Vag1382_23220	COG3385	transposase activity
Vag1382_23240	COG3344	reverse transcriptase
Vag1382_23270	COG0668	transmembrane transport
Vag1382_23280	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
Vag1382_23370	COG0681	Belongs to the peptidase S26 family
Vag1382_23400	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
Vag1382_23640	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
Vag1382_23760	COG3153	acetyltransferase
Vag1382_23770	COG3154	lipid carrier protein
Vag1382_23790	COG0826	peptidase U32
Vag1382_23800	COG0826	peptidase U32
Vag1382_23810	COG0534	Mate efflux family protein
Vag1382_23840	COG1185	polyribonucleotide nucleotidyltransferase activity
Vag1382_23850	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
Vag1382_23860	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
Vag1382_23870	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
Vag1382_23880	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
Vag1382_23890	COG0195	Participates in both transcription termination and antitermination
Vag1382_23900	COG0779	Required for maturation of 30S ribosomal subunits
Vag1382_23910	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
Vag1382_23920	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
Vag1382_23930	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
Vag1382_23940	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Vag1382_23950	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
Vag1382_23960	COG1534	Rna-binding protein
Vag1382_23970	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
Vag1382_23980	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
Vag1382_23990	COG2027	D-alanyl-D-alanine carboxypeptidase
Vag1382_24010	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
Vag1382_24020	COG0739	heme binding
Vag1382_24060	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
Vag1382_24070	COG0628	permease
Vag1382_24090	COG2205	protein histidine kinase activity
Vag1382_24090	COG0784	Response regulator, receiver
Vag1382_24100	COG0747	negative chemotaxis
Vag1382_24130	COG0444	Belongs to the ABC transporter superfamily
Vag1382_24140	COG4608	Belongs to the ABC transporter superfamily
Vag1382_24160	COG2971	BadF BadG BcrA BcrD
Vag1382_24190	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
Vag1382_24200	COG3842	ATPase activity
Vag1382_24220	COG1840	ABC-type Fe3 transport system, periplasmic component
Vag1382_24230	COG0004	ammonium transporteR
Vag1382_24240	COG0347	Belongs to the P(II) protein family
Vag1382_24250	COG3112	Uncharacterised protein family (UPF0231)
Vag1382_24260	COG1049	propionate catabolic process, 2-methylcitrate cycle
Vag1382_24270	COG1752	Esterase of the alpha-beta hydrolase superfamily
Vag1382_24280	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
Vag1382_24290	COG1643	Atp-dependent helicase
Vag1382_24300	COG1489	DNA binding
Vag1382_24320	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
Vag1382_24340	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
Vag1382_24350	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
Vag1382_24360	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
Vag1382_24370	COG1560	Kdo2-lipid A biosynthetic process
Vag1382_24380	COG0842	Transport permease protein
Vag1382_24390	COG1131	(ABC) transporter
Vag1382_24400	COG0659	secondary active sulfate transmembrane transporter activity
Vag1382_24410	COG0288	reversible hydration of carbon dioxide
Vag1382_24440	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Vag1382_24450	COG0508	dehydrogenase complex catalyzes the overall conversion of
Vag1382_24460	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
Vag1382_24470	COG2186	Transcriptional regulator
Vag1382_24490	COG0157	Belongs to the NadC ModD family
Vag1382_24510	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
Vag1382_24520	COG1459	type II secretion system
Vag1382_24540	COG0237	dephospho-CoA kinase activity
Vag1382_24550	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
Vag1382_24560	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
Vag1382_24590	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
Vag1382_24600	COG0228	four-way junction DNA binding
Vag1382_24610	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
Vag1382_24620	COG4137	Cytochrome C assembly protein
Vag1382_24630	COG4536	flavin adenine dinucleotide binding
Vag1382_24640	COG1854	S-ribosylhomocysteine lyase activity
Vag1382_24670	COG0612	Peptidase, M16
Vag1382_24680	COG1238	metal cluster binding
Vag1382_24700	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
Vag1382_24710	COG5016	pyruvate
Vag1382_24710	COG0511	ligase activity, forming carbon-carbon bonds
Vag1382_24720	COG3630	sodium ion export across plasma membrane
Vag1382_24740	COG0527	aspartate kinase activity
Vag1382_24750	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
Vag1382_24760	COG2137	regulation of response to DNA damage stimulus
Vag1382_24770	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
Vag1382_24780	COG1546	Belongs to the CinA family
Vag1382_24790	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
Vag1382_24800	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
Vag1382_24820	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
Vag1382_24830	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
Vag1382_24850	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
Vag1382_24860	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
Vag1382_24870	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
Vag1382_24880	COG0148	phosphopyruvate hydratase activity
Vag1382_24890	COG0504	CTP synthase activity
Vag1382_24900	COG3956	TIGRFAM MazG family protein
Vag1382_24910	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
Vag1382_24920	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
Vag1382_24940	COG0736	holo-[acyl-carrier-protein] synthase activity
Vag1382_24950	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
Vag1382_24960	COG1381	Involved in DNA repair and RecF pathway recombination
Vag1382_24970	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
Vag1382_24990	COG0681	Belongs to the peptidase S26 family
Vag1382_25000	COG0481	GTPase activity
Vag1382_25010	COG3086	response to oxidative stress
Vag1382_25040	COG1595	DNA-templated transcription, initiation
Vag1382_25050	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
Vag1382_25070	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
Vag1382_25080	COG0354	folic acid binding
Vag1382_25110	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Vag1382_25120	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Vag1382_25130	COG3079	Belongs to the UPF0149 family
Vag1382_25140	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
Vag1382_25150	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
Vag1382_25160	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
Vag1382_25170	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Vag1382_25190	COG0583	DNA-binding transcription factor activity
Vag1382_25220	COG0668	transmembrane transport
Vag1382_25230	COG0191	fructose-bisphosphate aldolase activity
Vag1382_25240	COG0126	phosphoglycerate kinase activity
Vag1382_25250	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
Vag1382_25260	COG4771	TonB-dependent receptor
Vag1382_25270	COG0583	DNA-binding transcription factor activity
Vag1382_25280	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
Vag1382_25290	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
Vag1382_25320	COG2356	endonuclease I
Vag1382_25330	COG1385	rRNA (uridine-N3-)-methyltransferase activity
Vag1382_25340	COG0189	ligase activity
Vag1382_25350	COG1678	Uncharacterized ACR, COG1678
Vag1382_25360	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
Vag1382_25390	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
Vag1382_25400	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
Vag1382_25410	COG0762	integral membrane protein
Vag1382_25420	COG1872	DUF167
Vag1382_25440	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
Vag1382_25450	COG0635	Involved in the biosynthesis of porphyrin-containing compound
Vag1382_25460	COG2066	Belongs to the glutaminase family
Vag1382_25480	COG0220	tRNA (guanine-N7-)-methyltransferase activity
Vag1382_25500	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
Vag1382_25540	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
Vag1382_25560	COG3394	polysaccharide catabolic process
Vag1382_25570	COG1486	melibiose metabolic process
Vag1382_25580	COG1447	Phosphotransferase system cellobiose-specific component IIA
Vag1382_25590	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
Vag1382_25600	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
Vag1382_25610	COG0726	polysaccharide deacetylase
Vag1382_25620	COG3706	GGDEF domain
Vag1382_25630	COG3547	Transposase (IS116 IS110 IS902 family)
Vag1382_25640	COG3547	Transposase (IS116 IS110 IS902 family)
Vag1382_25920	COG1028	Short-chain dehydrogenase reductase Sdr
Vag1382_25950	COG0795	lipopolysaccharide-transporting ATPase activity
Vag1382_25960	COG0795	lipopolysaccharide-transporting ATPase activity
Vag1382_25980	COG2927	DNA polymerase III (CHI subunit)
Vag1382_25990	COG0525	valine-tRNA ligase activity
Vag1382_26070	COG0540	Belongs to the ATCase OTCase family
Vag1382_26080	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
Vag1382_26090	COG0251	oxidation-reduction process
Vag1382_26100	COG0204	Acyl-transferase
Vag1382_26120	COG5007	Belongs to the BolA IbaG family
Vag1382_26140	COG2854	intermembrane phospholipid transfer
Vag1382_26150	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
Vag1382_26160	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
Vag1382_26170	COG1127	ABC transporter
Vag1382_26190	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
Vag1382_26190	COG0517	IMP dehydrogenase activity
Vag1382_26210	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
Vag1382_26220	COG1137	ATPase activity
Vag1382_26240	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
Vag1382_26250	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
Vag1382_26260	COG1660	Displays ATPase and GTPase activities
Vag1382_26270	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
Vag1382_26280	COG2239	Acts as a magnesium transporter
Vag1382_26290	COG0312	modulator of DNA gyrase
Vag1382_26300	COG3028	Belongs to the UPF0307 family
Vag1382_26310	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
Vag1382_26320	COG0564	pseudouridine synthase activity
Vag1382_26340	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
Vag1382_26350	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
Vag1382_26360	COG0312	modulator of DNA gyrase
Vag1382_26370	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
Vag1382_26380	COG3164	Protein of unknown function
Vag1382_26390	COG1530	ribonuclease E activity
Vag1382_26400	COG0424	maF-like protein
Vag1382_26410	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
Vag1382_26420	COG1792	Involved in formation and maintenance of cell shape
Vag1382_26430	COG1077	Cell shape determining protein MreB Mrl
Vag1382_26520	COG1459	type II secretion system
Vag1382_26530	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
Vag1382_26550	COG3267	Type II secretory pathway component ExeA
Vag1382_26550	COG3409	Peptidoglycan-binding domain 1 protein
Vag1382_26560	COG1450	Type ii and iii secretion system protein
Vag1382_26600	COG2200	EAL domain
Vag1382_26600	COG2199	diguanylate cyclase activity
Vag1382_26620	COG0629	single-stranded DNA binding
Vag1382_26650	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
Vag1382_26670	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
Vag1382_26680	COG0527	aspartate kinase activity
Vag1382_26690	COG1410	methionine synthase
Vag1382_26690	COG0646	methionine synthase
Vag1382_26730	COG0175	sulfate reduction
Vag1382_26740	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
Vag1382_26750	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
Vag1382_26790	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
Vag1382_26840	COG0247	lactate metabolic process
Vag1382_26850	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
Vag1382_26860	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
Vag1382_27000	COG0735	belongs to the Fur family
Vag1382_27020	COG0166	Belongs to the GPI family
Vag1382_27040	COG0432	Pfam Uncharacterised protein family UPF0047
Vag1382_27050	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
Vag1382_27100	COG2965	DNA replication, synthesis of RNA primer
Vag1382_27110	COG0360	Binds together with S18 to 16S ribosomal RNA
Vag1382_27120	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
Vag1382_27130	COG0338	D12 class N6 adenine-specific DNA methyltransferase
Vag1382_27150	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
Vag1382_27160	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
Vag1382_27220	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
Vag1382_27240	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
Vag1382_27240	COG0678	peroxiredoxin activity
Vag1382_27250	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Vag1382_27280	COG0165	Argininosuccinate lyase
Vag1382_27280	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
Vag1382_27290	COG0137	argininosuccinate synthase activity
Vag1382_27310	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
Vag1382_27330	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
Vag1382_27350	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
Vag1382_27360	COG0460	homoserine dehydrogenase
Vag1382_27360	COG0527	aspartate kinase activity
Vag1382_27370	COG0626	cystathionine gamma-synthase activity
Vag1382_27390	COG0281	malic enzyme
Vag1382_27410	COG2906	2 iron, 2 sulfur cluster binding
Vag1382_27420	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
Vag1382_27430	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
Vag1382_27470	COG2923	Belongs to the DsrF TusC family
Vag1382_27480	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
Vag1382_27490	COG2964	Protein conserved in bacteria
Vag1382_27500	COG0545	Peptidyl-prolyl cis-trans isomerase
Vag1382_27530	COG1446	asparaginase
Vag1382_27540	COG1047	Peptidyl-prolyl cis-trans
Vag1382_27570	COG2249	NAD(P)H dehydrogenase (quinone) activity
Vag1382_27580	COG0488	(ABC) transporter
Vag1382_27600	COG0429	hydrolase of the alpha beta-hydrolase fold
Vag1382_27610	COG3089	Belongs to the UPF0270 family
Vag1382_27620	COG3954	Phosphoribulokinase
Vag1382_27630	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Vag1382_27670	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
Vag1382_27680	COG0512	Glutamine amidotransferase of anthranilate synthase
Vag1382_27710	COG0180	Tryptophanyl-tRNA synthetase
Vag1382_27720	COG0546	phosphoglycolate phosphatase activity
Vag1382_27730	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
Vag1382_27740	COG0557	exoribonuclease II activity
Vag1382_27750	COG1959	2 iron, 2 sulfur cluster binding
Vag1382_27760	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
Vag1382_27760	COG1017	nitric oxide dioxygenase activity
Vag1382_27770	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
Vag1382_27780	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
Vag1382_27790	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
Vag1382_27800	COG0330	HflC and HflK could
Vag1382_27810	COG0330	HflC and HflK could
Vag1382_27820	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
Vag1382_27840	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
Vag1382_27850	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
Vag1382_27870	COG0802	atpase or kinase
Vag1382_27880	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
Vag1382_27890	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
Vag1382_27900	COG1162	GTPase activity
Vag1382_27910	COG0688	phosphatidylethanolamine metabolic process
Vag1382_27920	COG0471	metal ion transport
Vag1382_27920	COG3273	potassium ion transport
Vag1382_27940	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
Vag1382_27950	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
Vag1382_27960	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
Vag1382_27970	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
Vag1382_27980	COG1045	serine acetyltransferase
Vag1382_27990	COG4942	peptidase
Vag1382_28030	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
Vag1382_28040	COG1053	succinate dehydrogenase
Vag1382_28050	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
Vag1382_28060	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
Vag1382_28100	COG1509	lysine 2,3-aminomutase activity
Vag1382_28110	COG1285	pathogenesis
Vag1382_28130	COG0459	protein refolding
Vag1382_28150	COG0534	Mate efflux family protein
Vag1382_28160	COG0205	6-phosphofructokinase activity
Vag1382_28170	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
Vag1382_28190	COG0745	RESPONSE REGULATOR receiver
Vag1382_28200	COG2205	protein histidine kinase activity
Vag1382_28220	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
Vag1382_28230	COG3030	protein affecting phage T7 exclusion by the F plasmid
Vag1382_28240	COG1027	Aspartate ammonia-lyase
Vag1382_28250	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
Vag1382_28260	COG4232	protein-disulfide reductase activity
Vag1382_28280	COG3263	regulation of cellular component size
Vag1382_28300	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
Vag1382_28350	COG2814	Major facilitator Superfamily
Vag1382_28380	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
Vag1382_28390	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
Vag1382_28400	COG0511	ligase activity, forming carbon-carbon bonds
Vag1382_28410	COG0439	Biotin carboxylase
Vag1382_28420	COG2264	protein methyltransferase activity
Vag1382_28430	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
Vag1382_28440	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
Vag1382_28460	COG0488	(ABC) transporter
Vag1382_28470	COG1982	Orn Lys Arg decarboxylase major
Vag1382_28480	COG0531	amino acid
Vag1382_28500	COG3710	Transcriptional regulator
Vag1382_28510	COG0789	Transcriptional regulator
Vag1382_28520	COG0138	bifunctional purine biosynthesis protein purh
Vag1382_28530	COG0151	Belongs to the GarS family
Vag1382_28560	COG1253	flavin adenine dinucleotide binding
Vag1382_28570	COG3068	Protein conserved in bacteria
Vag1382_28590	COG1573	uracil-dna glycosylase
Vag1382_28600	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
Vag1382_28610	COG2816	NAD+ diphosphatase activity
Vag1382_28620	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
Vag1382_28630	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
Vag1382_28640	COG0085	RNA polymerase activity
Vag1382_28650	COG0222	ribosome binding
Vag1382_28660	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
Vag1382_28690	COG0250	Participates in transcription elongation, termination and antitermination
Vag1382_28700	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
Vag1382_28710	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
Vag1382_28730	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
Vag1382_28730	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
Vag1382_28740	COG0812	UDP-N-acetylmuramate dehydrogenase activity
Vag1382_28760	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
Vag1382_28800	COG4206	TonB-dependent receptor
Vag1382_28840	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Vag1382_28850	COG0534	Mate efflux family protein
Vag1382_28860	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
Vag1382_28870	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
Vag1382_28880	COG2937	Belongs to the GPAT DAPAT family
Vag1382_28890	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
Vag1382_28900	COG3161	chorismate lyase activity
Vag1382_28910	COG1580	Controls the rotational direction of flagella during chemotaxis
Vag1382_28920	COG0705	Rhomboid family
Vag1382_28930	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
Vag1382_28950	COG2177	Part of the ABC transporter FtsEX involved in
Vag1382_28960	COG2884	Cell division ATP-binding protein ftsE
Vag1382_28970	COG0552	protein localization to endoplasmic reticulum
Vag1382_28980	COG0742	ribosomal rna small subunit methyltransferase
Vag1382_29000	COG2095	MarC family integral membrane protein
Vag1382_29090	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
Vag1382_29100	COG0640	Transcriptional regulator
Vag1382_29110	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
Vag1382_29120	COG1280	lysine exporter protein (LysE YggA)
Vag1382_29130	COG2267	carboxylic ester hydrolase activity
Vag1382_29140	COG0561	phosphatase activity
Vag1382_29180	COG3287	FIST C domain
Vag1382_29180	COG2200	EAL domain
Vag1382_29180	COG2199	diguanylate cyclase activity
Vag1382_29190	COG1011	Hydrolase
Vag1382_29200	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
Vag1382_29220	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
Vag1382_29230	COG0019	diaminopimelate decarboxylase activity
Vag1382_29240	COG1965	Belongs to the frataxin family
Vag1382_29260	COG3072	Adenylate cyclase
Vag1382_29270	COG0181	hydroxymethylbilane synthase activity
Vag1382_29280	COG1587	Uroporphyrinogen-III synthase
Vag1382_29290	COG2959	enzyme of heme biosynthesis
Vag1382_29300	COG3071	HemY protein
Vag1382_29320	COG0633	Ferredoxin
Vag1382_29330	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
Vag1382_29360	COG3118	belongs to the thioredoxin family
Vag1382_29370	COG0513	Belongs to the DEAD box helicase family
Vag1382_29380	COG0248	Ppx GppA phosphatase
Vag1382_29390	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
Vag1382_29410	COG0514	ATP-dependent DNA helicase (RecQ)
Vag1382_29420	COG2962	Rard protein
Vag1382_29440	COG1280	lysine exporter protein (LysE YggA)
Vag1382_29450	COG0405	Gamma-glutamyltransferase
Vag1382_29470	COG0210	DNA helicase
Vag1382_29490	COG3220	belongs to the UPF0276 family
Vag1382_29550	COG0006	proline dipeptidase activity
Vag1382_29550	COG0006	proline dipeptidase activity
Vag1382_29590	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
Vag1382_29620	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
Vag1382_29630	COG2132	Multicopper oxidase
Vag1382_29640	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
Vag1382_29660	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
Vag1382_29670	COG0408	coproporphyrinogen oxidase activity
Vag1382_29680	COG0009	L-threonylcarbamoyladenylate synthase
Vag1382_29690	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
Vag1382_29700	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
Vag1382_29710	COG0551	DNA topoisomerase type I activity
Vag1382_29720	COG2922	Belongs to the Smg family
Vag1382_29730	COG0758	DNA mediated transformation
Vag1382_29750	COG0242	peptide deformylase activity
Vag1382_29760	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
Vag1382_29770	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
Vag1382_29770	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
Vag1382_29780	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
Vag1382_29780	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
Vag1382_29790	COG0569	domain protein
Vag1382_29800	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
Vag1382_29820	COG1272	protein, Hemolysin III
Vag1382_29830	COG4326	sporulation control protein
Vag1382_29850	COG3084	Protein conserved in bacteria
Vag1382_29870	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
Vag1382_29880	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
Vag1382_29890	COG0204	Acyl-transferase
Vag1382_29910	COG0606	chelatase, subunit chli
Vag1382_29930	COG3978	acetolactate synthase activity
Vag1382_29940	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
Vag1382_29950	COG0129	dihydroxy-acid dehydratase activity
Vag1382_29970	COG0583	DNA-binding transcription factor activity
Vag1382_29980	COG2814	Major facilitator Superfamily
Vag1382_30000	COG0765	amino acid transport
Vag1382_30020	COG0355	proton-transporting ATP synthase activity, rotational mechanism
Vag1382_30030	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
Vag1382_30040	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
Vag1382_30050	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
Vag1382_30060	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
Vag1382_30070	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
Vag1382_30090	COG0356	it plays a direct role in the translocation of protons across the membrane
Vag1382_30100	COG3312	ion transport
Vag1382_30110	COG1475	DNA binding
Vag1382_30120	COG1192	Involved in chromosome partitioning
Vag1382_30130	COG0357	Ribosomal RNA small subunit methyltransferase G
Vag1382_30140	COG0445	tRNA wobble uridine modification
Vag1382_30150	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
Vag1382_30170	COG3706	GGDEF domain
Vag1382_30200	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
Vag1382_30210	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
Vag1382_30230	COG1609	Transcriptional regulator
Vag1382_30440	COG4974	Belongs to the 'phage' integrase family
Vag1382_30460	COG0706	membrane insertase activity
Vag1382_30470	COG0594	ribonuclease P activity
Vag1382_30490	COG1126	abc transporter atp-binding protein
Vag1382_30540	COG4608	Belongs to the ABC transporter superfamily
Vag1382_30550	COG0444	Belongs to the ABC transporter superfamily
Vag1382_30570	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
Vag1382_30570	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
Vag1382_30620	COG0772	Belongs to the SEDS family
Vag1382_30640	COG1136	(ABC) transporter
Vag1382_30680	COG3275	phosphorelay sensor kinase activity
Vag1382_30690	COG3279	Response regulator of the LytR AlgR family
Vag1382_30710	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
Vag1382_30750	COG0786	glutamate:sodium symporter activity
Vag1382_30770	COG1131	(ABC) transporter
Vag1382_30780	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Vag1382_30790	COG0786	glutamate:sodium symporter activity
Vag1382_30810	COG0363	glucosamine-6-phosphate deaminase activity
Vag1382_30850	COG1741	Belongs to the pirin family
Vag1382_30860	COG2259	Doxx family
Vag1382_30880	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
Vag1382_30890	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
Vag1382_30910	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
Vag1382_30970	COG0596	Alpha beta hydrolase
Vag1382_31000	COG3123	guanosine phosphorylase activity
Vag1382_31030	COG0534	Mate efflux family protein
Vag1382_31040	COG0564	pseudouridine synthase activity
Vag1382_31070	COG0583	DNA-binding transcription factor activity
Vag1382_31080	COG0561	phosphatase activity
Vag1382_31100	COG2199	diguanylate cyclase activity
Vag1382_31130	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
Vag1382_31140	COG2162	N-hydroxyarylamine O-acetyltransferase activity
Vag1382_31150	COG0583	DNA-binding transcription factor activity
Vag1382_31230	COG1357	PFAM Pentapeptide repeats (8 copies)
Vag1382_31240	COG3047	cAMP biosynthetic process
Vag1382_31300	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
Vag1382_31300	COG3408	Glycogen debranching enzyme
Vag1382_31310	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
Vag1382_31350	COG0583	DNA-binding transcription factor activity
Vag1382_31380	COG0546	phosphoglycolate phosphatase activity
Vag1382_31430	COG3835	regulator
Vag1382_31440	COG2610	gluconate transmembrane transporter activity
Vag1382_31450	COG1929	Belongs to the glycerate kinase type-1 family
Vag1382_31460	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Vag1382_31500	COG0456	acetyltransferase
Vag1382_31530	COG1028	Short-chain dehydrogenase reductase Sdr
Vag1382_31540	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Vag1382_31550	COG3005	denitrification pathway
Vag1382_31560	COG0243	molybdopterin cofactor binding
Vag1382_31580	COG0352	thiamine-phosphate diphosphorylase activity
Vag1382_31590	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
Vag1382_31600	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
Vag1382_31610	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Vag1382_31620	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Vag1382_31630	COG1116	anion transmembrane transporter activity
Vag1382_31640	COG0351	phosphomethylpyrimidine kinase
Vag1382_31650	COG0312	modulator of DNA gyrase
Vag1382_31660	COG0312	modulator of DNA gyrase
Vag1382_31670	COG1901	pseudouridine methyltransferase
Vag1382_31720	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
Vag1382_31740	COG0584	glycerophosphoryl diester phosphodiesterase
Vag1382_31750	COG0039	L-malate dehydrogenase activity
Vag1382_31760	COG0745	RESPONSE REGULATOR receiver
Vag1382_31800	COG0811	peptide transport
Vag1382_31810	COG0811	peptide transport
Vag1382_31820	COG0848	biopolymer transport protein
Vag1382_31910	COG0803	Belongs to the bacterial solute-binding protein 9 family
Vag1382_31920	COG1121	(ABC) transporter
Vag1382_31930	COG1108	ABC-type Mn2 Zn2 transport systems permease components
Vag1382_31960	COG1770	oligopeptidase
Vag1382_31970	COG2814	Major facilitator Superfamily
Vag1382_31980	COG0010	Belongs to the arginase family
Vag1382_31990	COG1166	arginine decarboxylase activity
Vag1382_32010	COG0189	ligase activity
Vag1382_32010	COG4067	protein conserved in archaea
Vag1382_32020	COG0189	ligase activity
Vag1382_32030	COG0583	DNA-binding transcription factor activity
Vag1382_32100	COG4191	Histidine kinase
Vag1382_32110	COG2204	response regulator
Vag1382_32120	COG3706	GGDEF domain
Vag1382_32160	COG0579	oxidoreductase
Vag1382_32180	COG1294	oxidase, subunit
Vag1382_32190	COG1271	oxidase subunit
Vag1382_32210	COG3033	Beta-eliminating lyase
Vag1382_32230	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
Vag1382_32260	COG3706	GGDEF domain
Vag1382_32290	COG3706	GGDEF domain
Vag1382_32300	COG0415	Belongs to the DNA photolyase family
Vag1382_32310	COG3046	protein related to deoxyribodipyrimidine photolyase
Vag1382_32330	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Vag1382_32330	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Vag1382_32340	COG1765	OsmC-like protein
Vag1382_32350	COG0110	maltose O-acetyltransferase activity
Vag1382_32430	COG1011	Hydrolase
Vag1382_32460	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
Vag1382_32470	COG3338	carbonate dehydratase activity
Vag1382_32480	COG2067	long-chain fatty acid transport protein
Vag1382_32490	COG3240	lipase activity
Vag1382_32550	COG1609	Transcriptional regulator
Vag1382_32560	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
Vag1382_32590	COG1840	ABC-type Fe3 transport system, periplasmic component
Vag1382_32600	COG3842	ATPase activity
Vag1382_32650	COG2990	Protein conserved in bacteria
Vag1382_32670	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Vag1382_32680	COG2866	Carboxypeptidase
Vag1382_32700	COG0583	DNA-binding transcription factor activity
Vag1382_32740	COG3104	oligopeptide transport
Vag1382_32750	COG1760	l-serine dehydratase
Vag1382_32790	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
Vag1382_32800	COG0741	lytic transglycosylase activity
Vag1382_32840	COG1815	bacterial-type flagellum-dependent cell motility
Vag1382_32850	COG1558	bacterial-type flagellum-dependent cell motility
Vag1382_32860	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
Vag1382_32870	COG1749	Flagellar hook protein flgE
Vag1382_32880	COG4787	bacterial-type flagellum-dependent cell motility
Vag1382_32890	COG4786	Flagellar basal body rod
Vag1382_32900	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
Vag1382_32910	COG1706	bacterial-type flagellum-dependent cell motility
Vag1382_32930	COG4786	Flagellar basal body rod
Vag1382_32930	COG1256	bacterial-type flagellum assembly
Vag1382_32940	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
Vag1382_32980	COG1304	FMN binding
Vag1382_33010	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
Vag1382_33020	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
Vag1382_33030	COG0459	protein refolding
Vag1382_33060	COG1280	lysine exporter protein (LysE YggA)
Vag1382_33100	COG1309	transcriptional regulator
Vag1382_33120	COG4303	Ethanolamine ammonia lyase large subunit
Vag1382_33130	COG4302	ethanolamine ammonia-lyase activity
Vag1382_33140	COG0531	amino acid
Vag1382_33150	COG2070	2-Nitropropane dioxygenase
Vag1382_33160	COG3537	Alpha-1,2-mannosidase
Vag1382_33170	COG3537	Alpha-1,2-mannosidase
Vag1382_33190	COG3537	Alpha-1,2-mannosidase
Vag1382_33200	COG3537	Alpha-1,2-mannosidase
Vag1382_33210	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
Vag1382_33230	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Vag1382_33230	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Vag1382_33240	COG0346	lactoylglutathione lyase activity
Vag1382_33250	COG1349	DNA-binding transcription factor activity
Vag1382_33270	COG1335	isochorismatase
Vag1382_33290	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
Vag1382_33340	COG0583	DNA-binding transcription factor activity
Vag1382_33370	COG3713	MltA-interacting MipA family protein
Vag1382_33380	COG3015	lipoprotein NlpE involved in copper resistance
Vag1382_33390	COG3448	diguanylate cyclase activity
Vag1382_33390	COG4175	Glycine betaine
Vag1382_33400	COG4176	ABC-type proline glycine betaine transport system permease component
Vag1382_33410	COG1342	Belongs to the UPF0251 family
Vag1382_33470	COG4948	Mandelate Racemase Muconate Lactonizing
Vag1382_33490	COG0583	DNA-binding transcription factor activity
Vag1382_33560	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
Vag1382_33630	COG3842	ATPase activity
Vag1382_33690	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
Vag1382_33750	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Vag1382_33780	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
Vag1382_33790	COG2197	response regulator
Vag1382_33820	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
Vag1382_33830	COG0252	asparaginase activity
Vag1382_33850	COG0583	DNA-binding transcription factor activity
Vag1382_33870	COG1280	lysine exporter protein (LysE YggA)
Vag1382_33880	COG3122	Protein conserved in bacteria
Vag1382_33900	COG2423	ornithine cyclodeaminase activity
Vag1382_33910	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
Vag1382_33920	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
Vag1382_33930	COG1012	belongs to the aldehyde dehydrogenase family
Vag1382_33940	COG1522	sequence-specific DNA binding
Vag1382_33950	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
Vag1382_33960	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
Vag1382_33970	COG3608	succinylglutamate desuccinylase aspartoacylase
Vag1382_33980	COG0006	proline dipeptidase activity
Vag1382_33990	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Vag1382_34000	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
Vag1382_34010	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
Vag1382_34020	COG2207	Transcriptional regulator
Vag1382_34030	COG1028	Short-chain dehydrogenase reductase Sdr
Vag1382_34050	COG1063	alcohol dehydrogenase
Vag1382_34060	COG1902	pentaerythritol trinitrate reductase activity
Vag1382_34090	COG0583	DNA-binding transcription factor activity
Vag1382_34110	COG0513	Belongs to the DEAD box helicase family
Vag1382_34150	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Vag1382_34160	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
Vag1382_34160	COG2207	Transcriptional regulator
Vag1382_34210	COG3746	phosphate-selective porin O and P
Vag1382_34240	COG1028	Short-chain dehydrogenase reductase Sdr
Vag1382_34300	COG1263	PTS System
Vag1382_34300	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
Vag1382_34310	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Vag1382_34320	COG1621	beta-fructofuranosidase activity
Vag1382_34330	COG0625	glutathione transferase activity
Vag1382_34350	COG1686	Belongs to the peptidase S11 family
Vag1382_34380	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
Vag1382_34380	COG0678	peroxiredoxin activity
Vag1382_34390	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
Vag1382_34400	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
Vag1382_34430	COG1278	Cold shock
Vag1382_34440	COG1741	Belongs to the pirin family
Vag1382_34450	COG4667	esterase of the alpha-beta hydrolase superfamily
Vag1382_34500	COG2194	sulfuric ester hydrolase activity
Vag1382_34510	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
Vag1382_34530	COG2205	protein histidine kinase activity
Vag1382_34540	COG0745	RESPONSE REGULATOR receiver
Vag1382_34570	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
Vag1382_34610	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
Vag1382_34630	COG2814	Major facilitator Superfamily
Vag1382_34650	COG1418	mRNA catabolic process
Vag1382_34660	COG0402	S-adenosylhomocysteine deaminase activity
Vag1382_34670	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
Vag1382_34680	COG2239	Acts as a magnesium transporter
Vag1382_34690	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
Vag1382_34700	COG1566	PFAM secretion protein HlyD family protein
Vag1382_34750	COG0745	RESPONSE REGULATOR receiver
Vag1382_34760	COG2205	protein histidine kinase activity
Vag1382_34790	COG0531	amino acid
Vag1382_34810	COG0583	DNA-binding transcription factor activity
Vag1382_34860	COG0784	Response regulator, receiver
Vag1382_34860	COG5002	protein histidine kinase activity
Vag1382_34860	COG2205	protein histidine kinase activity
Vag1382_34870	COG0534	Mate efflux family protein
Vag1382_34900	COG3132	Protein of unknown function, DUF480
Vag1382_34910	COG2827	Endonuclease containing a URI domain
Vag1382_34920	COG1879	ABC-type sugar transport system periplasmic component
Vag1382_34930	COG2205	protein histidine kinase activity
Vag1382_34930	COG0784	Response regulator, receiver
Vag1382_35040	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
Vag1382_35050	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
Vag1382_35070	COG1280	lysine exporter protein (LysE YggA)
Vag1382_35090	COG0183	Belongs to the thiolase family
Vag1382_35110	COG3243	poly(R)-hydroxyalkanoic acid synthase
Vag1382_35130	COG3005	denitrification pathway
Vag1382_35150	COG0243	molybdopterin cofactor binding
Vag1382_35170	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
Vag1382_35180	COG3850	Histidine kinase
Vag1382_35190	COG2197	response regulator
Vag1382_35220	COG2195	Cleaves the N-terminal amino acid of tripeptides
Vag1382_35260	COG0840	transmembrane signaling receptor activity
Vag1382_35280	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
Vag1382_35300	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
Vag1382_35310	COG2814	Major facilitator Superfamily
Vag1382_35320	COG0840	transmembrane signaling receptor activity
Vag1382_35330	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
Vag1382_35340	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
Vag1382_35380	COG2897	thiosulfate sulfurtransferase activity
Vag1382_35420	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
Vag1382_35450	COG1914	H( )-stimulated, divalent metal cation uptake system
Vag1382_35470	COG0038	chloride channel
Vag1382_35500	COG4989	oxidoreductase activity
Vag1382_35530	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
Vag1382_35530	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
Vag1382_35550	COG1013	pyruvate-flavodoxin oxidoreductase activity
Vag1382_35560	COG0674	pyruvate-flavodoxin oxidoreductase activity
Vag1382_35560	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
Vag1382_35580	COG0739	heme binding
Vag1382_35670	COG3501	Rhs element vgr protein
Vag1382_35720	COG0515	serine threonine protein kinase
Vag1382_35790	COG1522	sequence-specific DNA binding
Vag1382_35930	COG2814	Major facilitator Superfamily
Vag1382_35950	COG0583	DNA-binding transcription factor activity
Vag1382_35960	COG4221	oxidoreductase activity
Vag1382_35970	COG0589	response to stress
Vag1382_35990	COG2111	Na H antiporter
Vag1382_35990	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
Vag1382_36030	COG2212	antiporter activity
Vag1382_36040	COG1320	monovalent cation:proton antiporter activity
Vag1382_36050	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
Vag1382_36180	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
Vag1382_36210	COG3527	Alpha-acetolactate decarboxylase
Vag1382_36270	COG0384	phenazine biosynthesis protein PhzF
Vag1382_36290	COG1294	oxidase, subunit
Vag1382_36300	COG1271	oxidase subunit
Vag1382_36310	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Vag1382_36350	COG4999	Histidine kinase
Vag1382_36350	COG3850	Histidine kinase
Vag1382_36350	COG3437	response regulator, receiver
Vag1382_36350	COG2205	protein histidine kinase activity
Vag1382_36370	COG4770	biotin carboxylase activity
Vag1382_36390	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
Vag1382_36400	COG1960	acyl-CoA dehydrogenase activity
Vag1382_36420	COG0183	Belongs to the thiolase family
Vag1382_36440	COG1960	acyl-CoA dehydrogenase activity
Vag1382_36450	COG1024	Enoyl-CoA hydratase
Vag1382_36480	COG1028	Short-chain dehydrogenase reductase Sdr
Vag1382_36500	COG1309	transcriptional regulator
Vag1382_36510	COG1012	belongs to the aldehyde dehydrogenase family
Vag1382_36540	COG4176	ABC-type proline glycine betaine transport system permease component
Vag1382_36550	COG0517	IMP dehydrogenase activity
Vag1382_36550	COG4175	Glycine betaine
Vag1382_36580	COG0330	HflC and HflK could
Vag1382_36610	COG3300	MHYT domain
Vag1382_36610	COG5001	Diguanylate cyclase
Vag1382_36640	COG2205	protein histidine kinase activity
Vag1382_36640	COG0784	Response regulator, receiver
Vag1382_36660	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
Vag1382_36750	COG5001	Diguanylate cyclase
Vag1382_36760	COG1869	D-ribose catabolic process
Vag1382_36770	COG1129	ABC transporter
Vag1382_36780	COG1172	Belongs to the binding-protein-dependent transport system permease family
Vag1382_36790	COG1879	ABC-type sugar transport system periplasmic component
Vag1382_36800	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Vag1382_36810	COG1609	Transcriptional regulator
Vag1382_36840	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
Vag1382_36860	COG4607	ABC-type enterochelin transport system periplasmic component
Vag1382_36870	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Vag1382_36880	COG4605	iron ion homeostasis
Vag1382_36890	COG4604	ABC transporter, ATP-binding protein
Vag1382_36900	COG0789	Transcriptional regulator
Vag1382_36910	COG2207	Transcriptional regulator
Vag1382_36920	COG4771	TonB-dependent receptor
Vag1382_36920	COG1629	transport
Vag1382_36980	COG1289	transmembrane transporter activity
Vag1382_36990	COG0210	DNA helicase
Vag1382_37000	COG1803	Methylglyoxal synthase
Vag1382_37010	COG1879	ABC-type sugar transport system periplasmic component
Vag1382_37020	COG2198	Histidine kinase
Vag1382_37020	COG0784	Response regulator, receiver
Vag1382_37020	COG2205	protein histidine kinase activity
Vag1382_37060	COG3119	arylsulfatase activity
Vag1382_37080	COG3119	arylsulfatase activity
Vag1382_37090	COG0641	radical SAM
Vag1382_37100	COG0714	Associated with various cellular activities
Vag1382_37160	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
Vag1382_37160	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
Vag1382_37170	COG0583	DNA-binding transcription factor activity
Vag1382_37180	COG1597	lipid kinase activity
Vag1382_37190	COG3111	PFAM Bacterial OB fold (BOF) protein
Vag1382_37250	COG0501	Belongs to the peptidase M48B family
Vag1382_37260	COG1704	LemA family
Vag1382_37270	COG3069	C4-dicarboxylate transmembrane transporter activity
Vag1382_37290	COG1214	PFAM Peptidase M22, glycoprotease
Vag1382_37290	COG0456	acetyltransferase
Vag1382_37330	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
Vag1382_37350	COG3706	GGDEF domain
Vag1382_37370	COG2197	response regulator
Vag1382_37380	COG0784	Response regulator, receiver
Vag1382_37380	COG0835	chemotaxis
Vag1382_37410	COG2962	Rard protein
Vag1382_37510	COG0471	metal ion transport
Vag1382_37520	COG3290	protein histidine kinase activity
Vag1382_37530	COG4565	transcriptional regulatory protein
Vag1382_37560	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
Vag1382_37570	COG5642	Protein of unknown function (DUF2384)
Vag1382_37590	COG2755	lipolytic protein G-D-S-L family
Vag1382_37590	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
Vag1382_37610	COG1902	pentaerythritol trinitrate reductase activity
Vag1382_37620	COG0346	lactoylglutathione lyase activity
Vag1382_37660	COG2239	Acts as a magnesium transporter
Vag1382_37700	COG0242	peptide deformylase activity
Vag1382_37780	COG2176	DNA-directed DNA polymerase activity
Vag1382_37840	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
Vag1382_37850	COG0346	lactoylglutathione lyase activity
Vag1382_37920	COG1979	alcohol dehydrogenase
Vag1382_37930	COG2207	Transcriptional regulator
Vag1382_37950	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
Vag1382_37960	COG2759	Belongs to the formate--tetrahydrofolate ligase family
Vag1382_37970	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Vag1382_38010	COG0546	phosphoglycolate phosphatase activity
Vag1382_38020	COG0840	transmembrane signaling receptor activity
Vag1382_38050	COG0513	Belongs to the DEAD box helicase family
Vag1382_38060	COG4943	cyclic-guanylate-specific phosphodiesterase activity
Vag1382_38090	COG3038	cytochrome b561
Vag1382_38100	COG2353	YceI-like domain
Vag1382_38110	COG2116	formate transmembrane transporter activity
Vag1382_38120	COG0583	DNA-binding transcription factor activity
Vag1382_38140	COG3593	DNA synthesis involved in DNA repair
Vag1382_38150	COG0737	Belongs to the 5'-nucleotidase family
Vag1382_38210	COG2267	carboxylic ester hydrolase activity
Vag1382_38220	COG2067	long-chain fatty acid transport protein
Vag1382_38250	COG2050	protein possibly involved in aromatic compounds catabolism
Vag1382_38270	COG4533	DNA binding
Vag1382_38340	COG5001	Diguanylate cyclase
Vag1382_38340	COG1716	ATPase activity
Vag1382_38350	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
Vag1382_38370	COG4181	ATPase activity
Vag1382_38380	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
Vag1382_38400	COG1984	allophanate hydrolase subunit 2
Vag1382_38410	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
Vag1382_38420	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
Vag1382_38430	COG3447	MASE1 domain protein
Vag1382_38430	COG5001	Diguanylate cyclase
Vag1382_38430	COG5002	protein histidine kinase activity
Vag1382_38440	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
Vag1382_38460	COG0583	DNA-binding transcription factor activity
Vag1382_38470	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Vag1382_38470	COG1042	CoA-binding domain protein
Vag1382_38470	COG0045	succinate-CoA ligase (ADP-forming) activity
Vag1382_38490	COG1181	Belongs to the D-alanine--D-alanine ligase family
Vag1382_38510	COG0023	Translation Initiation Factor
Vag1382_38530	COG4128	Pfam Zonular occludens toxin
Vag1382_38630	COG4128	Pfam Zonular occludens toxin
Vag1382_38750	COG0583	DNA-binding transcription factor activity
Vag1382_38770	COG0589	response to stress
Vag1382_38780	COG3140	Belongs to the UPF0181 family
Vag1382_38830	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
Vag1382_38840	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
Vag1382_38890	COG2203	Gaf domain
Vag1382_38890	COG5001	Diguanylate cyclase
Vag1382_38890	COG4251	negative regulation of phosphorylation
Vag1382_38890	COG3706	GGDEF domain
Vag1382_38910	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
Vag1382_38920	COG4149	molybdate abc transporter
Vag1382_38930	COG0725	ABC transporter, periplasmic molybdate-binding protein
Vag1382_38970	COG4067	protein conserved in archaea
Vag1382_38970	COG0189	ligase activity
Vag1382_38990	COG2207	Transcriptional regulator
Vag1382_39000	COG0534	Mate efflux family protein
Vag1382_39010	COG0602	queuosine metabolic process
Vag1382_39020	COG1328	CTP reductase activity
Vag1382_39050	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Vag1382_39110	COG1794	racemase activity, acting on amino acids and derivatives
Vag1382_39120	COG0384	phenazine biosynthesis protein PhzF
Vag1382_39140	COG0243	molybdopterin cofactor binding
Vag1382_39150	COG0583	DNA-binding transcription factor activity
Vag1382_39160	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
Vag1382_39180	COG2197	response regulator
Vag1382_39190	COG3851	Histidine kinase
Vag1382_39200	COG2271	Major facilitator Superfamily
Vag1382_39250	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
Vag1382_39260	COG3118	belongs to the thioredoxin family
Vag1382_39330	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
Vag1382_39370	COG2116	formate transmembrane transporter activity
Vag1382_39390	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
Vag1382_39400	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
Vag1382_39410	COG5001	Diguanylate cyclase
Vag1382_39510	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
Vag1382_39580	COG0277	FAD linked oxidase domain protein
Vag1382_39590	COG0583	DNA-binding transcription factor activity
Vag1382_39600	COG2425	protein containing a von Willebrand factor type A (vWA) domain
Vag1382_39630	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
Vag1382_39650	COG1288	antiporter activity
Vag1382_39670	COG3040	lipid binding
Vag1382_39690	COG0419	ATPase involved in DNA repair
Vag1382_39700	COG0420	3'-5' exonuclease activity
Vag1382_39730	COG3501	Rhs element vgr protein
Vag1382_39840	COG0631	protein serine/threonine phosphatase activity
Vag1382_39910	COG0515	serine threonine protein kinase
Vag1382_39910	COG2815	serine threonine protein kinase
Vag1382_39950	COG0745	RESPONSE REGULATOR receiver
Vag1382_39970	COG0625	glutathione transferase activity
Vag1382_40010	COG2146	nitrite reductase [NAD(P)H] activity
Vag1382_40010	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
Vag1382_40020	COG1116	anion transmembrane transporter activity
Vag1382_40030	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Vag1382_40040	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Vag1382_40040	COG1116	anion transmembrane transporter activity
Vag1382_40090	COG0243	molybdopterin cofactor binding
Vag1382_40110	COG0814	amino acid
Vag1382_40130	COG3706	GGDEF domain
Vag1382_40230	COG2847	Copper chaperone PCu(A)C
Vag1382_40240	COG0443	Heat shock 70 kDa protein
Vag1382_40370	COG4160	amino acid transport
Vag1382_40380	COG4215	(ABC) transporter
Vag1382_40390	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Vag1382_40400	COG1126	abc transporter atp-binding protein
Vag1382_40460	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
Vag1382_40480	COG1012	belongs to the aldehyde dehydrogenase family
Vag1382_40520	COG1902	pentaerythritol trinitrate reductase activity
Vag1382_40520	COG0446	pyridine nucleotide-disulphide oxidoreductase
Vag1382_40540	COG0109	protoheme IX farnesyltransferase activity
Vag1382_40550	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
Vag1382_40560	COG1845	cytochrome c oxidase, subunit III
Vag1382_40570	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
Vag1382_40580	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
Vag1382_40590	COG1028	Short-chain dehydrogenase reductase Sdr
Vag1382_40610	COG1024	Enoyl-CoA hydratase
Vag1382_40620	COG1024	Enoyl-CoA hydratase
Vag1382_40650	COG0183	Belongs to the thiolase family
Vag1382_40670	COG1960	acyl-CoA dehydrogenase activity
Vag1382_40680	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
Vag1382_40690	COG1024	Enoyl-CoA hydratase
Vag1382_40710	COG5413	integral membrane protein
Vag1382_40730	COG0247	lactate metabolic process
Vag1382_40730	COG0277	FAD linked oxidase domain protein
Vag1382_40840	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
Vag1382_40860	COG0513	Belongs to the DEAD box helicase family
Vag1382_40870	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
Vag1382_40920	COG0840	transmembrane signaling receptor activity
Vag1382_40930	COG1119	ATPase activity
Vag1382_40940	COG2200	EAL domain
Vag1382_40990	COG0513	Belongs to the DEAD box helicase family
Vag1382_41000	COG0523	cobalamin synthesis protein
Vag1382_41020	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
Vag1382_41040	COG1278	Cold shock
Vag1382_41050	COG0557	exoribonuclease II activity
Vag1382_41060	COG0133	tryptophan synthase activity
Vag1382_41080	COG4628	conserved protein (DUF2132)
Vag1382_41090	COG0513	Belongs to the DEAD box helicase family
Vag1382_41110	COG0730	response to heat
Vag1382_41140	COG0697	spore germination
Vag1382_41150	COG1982	Orn Lys Arg decarboxylase major
Vag1382_41160	COG1335	isochorismatase
Vag1382_41180	COG1404	Belongs to the peptidase S8 family
Vag1382_41210	COG3530	Putative quorum-sensing-regulated virulence factor
Vag1382_41260	COG3186	Phenylalanine-4-hydroxylase
Vag1382_41270	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
Vag1382_41280	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
Vag1382_41330	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
Vag1382_41340	COG1454	alcohol dehydrogenase
Vag1382_41350	COG2133	pyrroloquinoline quinone binding
Vag1382_41370	COG0783	Belongs to the Dps family
Vag1382_41380	COG0840	transmembrane signaling receptor activity
Vag1382_41400	COG0577	efflux transmembrane transporter activity
Vag1382_41400	COG1136	(ABC) transporter
Vag1382_41440	COG2199	diguanylate cyclase activity
Vag1382_41450	COG3036	rescue of stalled ribosome
Vag1382_41460	COG1278	Cold shock
Vag1382_41500	COG2885	chlorophyll binding
Vag1382_41520	COG0545	Peptidyl-prolyl cis-trans isomerase
Vag1382_41530	COG0109	protoheme IX farnesyltransferase activity
Vag1382_41540	COG1612	heme a metabolic process
Vag1382_41580	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
Vag1382_41590	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
Vag1382_41600	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
Vag1382_41610	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
Vag1382_41630	COG1280	lysine exporter protein (LysE YggA)
Vag1382_41640	COG2207	Transcriptional regulator
Vag1382_41670	COG0179	Fumarylacetoacetate (FAA) hydrolase
Vag1382_41710	COG0697	spore germination
Vag1382_41750	COG2814	Major facilitator Superfamily
Vag1382_41760	COG0583	DNA-binding transcription factor activity
Vag1382_41770	COG5001	Diguanylate cyclase
Vag1382_41780	COG0739	heme binding
Vag1382_41840	COG0840	transmembrane signaling receptor activity
Vag1382_41860	COG0814	amino acid
Vag1382_41890	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
Vag1382_41900	COG1072	(Pantothenic acid kinase))
Vag1382_41920	COG1063	alcohol dehydrogenase
Vag1382_41930	COG2213	PTS system mannitol-specific
Vag1382_41940	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
Vag1382_41970	COG0798	PFAM Bile acid sodium symporter
Vag1382_41990	COG1881	PFAM PEBP family protein
Vag1382_42010	COG2706	6-phosphogluconolactonase activity
Vag1382_42030	COG1131	(ABC) transporter
Vag1382_42040	COG0842	Transport permease protein
Vag1382_42070	COG3383	formate dehydrogenase (NAD+) activity
Vag1382_42110	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Vag1382_42170	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Vag1382_42190	COG2067	long-chain fatty acid transport protein
Vag1382_42210	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Vag1382_42240	COG1505	serine-type exopeptidase activity
Vag1382_42250	COG0488	(ABC) transporter
Vag1382_42260	COG0589	response to stress
Vag1382_42270	COG2249	NAD(P)H dehydrogenase (quinone) activity
Vag1382_42310	COG0366	Alpha amylase catalytic
Vag1382_42320	COG0789	Transcriptional regulator
Vag1382_42350	COG4934	collagen metabolic process
Vag1382_42370	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
Vag1382_42380	COG0583	DNA-binding transcription factor activity
Vag1382_42450	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
Vag1382_42460	COG0784	Response regulator, receiver
Vag1382_42460	COG0835	chemotaxis
Vag1382_42480	COG0748	coenzyme F420 binding
Vag1382_42490	COG3721	Heme iron utilization protein
Vag1382_42510	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
Vag1382_42520	COG0811	peptide transport
Vag1382_42530	COG0848	biopolymer transport protein
Vag1382_42550	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Vag1382_42560	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
Vag1382_42650	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
Vag1382_42660	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
Vag1382_42670	COG3217	Mosc domain protein beta barrel domain protein
Vag1382_42670	COG0633	Ferredoxin
Vag1382_42670	COG3217	Mosc domain protein beta barrel domain protein
Vag1382_42670	COG0633	Ferredoxin
Vag1382_42680	COG0401	homolog of Blt101
Vag1382_42690	COG0418	dihydroorotase activity
Vag1382_42700	COG2354	Protein conserved in bacteria
Vag1382_42760	COG3833	ABC-type maltose transport systems, permease component
Vag1382_42770	COG1175	transmembrane transport
Vag1382_42790	COG3842	ATPase activity
Vag1382_42800	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
Vag1382_42920	COG1309	transcriptional regulator
Vag1382_42930	COG2130	NADP-dependent
Vag1382_42950	COG0753	catalase activity
Vag1382_42960	COG2084	Dehydrogenase
Vag1382_42970	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
Vag1382_42980	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
Vag1382_43000	COG2207	Transcriptional regulator
Vag1382_43010	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
Vag1382_43010	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
Vag1382_43010	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
Vag1382_43040	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
Vag1382_43050	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
Vag1382_43060	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
Vag1382_43080	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Vag1382_43090	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
Vag1382_43100	COG1012	belongs to the aldehyde dehydrogenase family
Vag1382_43130	COG0583	DNA-binding transcription factor activity
Vag1382_43140	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
Vag1382_43150	COG0569	domain protein
Vag1382_43170	COG2205	protein histidine kinase activity
Vag1382_43170	COG2205	protein histidine kinase activity
Vag1382_43180	COG1132	(ABC) transporter
Vag1382_43190	COG4774	siderophore transport
Vag1382_43200	COG1120	ATPase activity
Vag1382_43210	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
Vag1382_43280	COG2197	response regulator
Vag1382_43300	COG0840	transmembrane signaling receptor activity
Vag1382_43310	COG0714	Associated with various cellular activities
Vag1382_43340	COG2304	oxidoreductase activity
Vag1382_43350	COG2304	oxidoreductase activity
Vag1382_43380	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
Vag1382_43390	COG0581	inorganic phosphate transmembrane transporter activity
Vag1382_43400	COG0573	inorganic phosphate transmembrane transporter activity
Vag1382_43460	COG4771	TonB-dependent receptor
Vag1382_43470	COG1770	oligopeptidase
Vag1382_43480	COG0513	Belongs to the DEAD box helicase family
Vag1382_43500	COG1388	LysM domain
Vag1382_43500	COG1376	ErfK ybiS ycfS ynhG family protein
Vag1382_43510	COG0415	Belongs to the DNA photolyase family
Vag1382_43520	COG0789	Transcriptional regulator
Vag1382_43530	COG3272	Protein of unknown function (DUF1722)
Vag1382_43540	COG0813	purine-nucleoside phosphorylase activity
Vag1382_43570	COG3706	GGDEF domain
Vag1382_43590	COG1566	PFAM secretion protein HlyD family protein
Vag1382_43600	COG4720	Psort location CytoplasmicMembrane, score
Vag1382_43610	COG1122	ATPase activity
Vag1382_43650	COG0348	domain, Protein
Vag1382_43660	COG0437	4 iron, 4 sulfur cluster binding
Vag1382_43670	COG1247	-acetyltransferase
Vag1382_43710	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
Vag1382_43720	COG0840	transmembrane signaling receptor activity
Vag1382_43730	COG1067	ATP-dependent peptidase activity
Vag1382_43750	COG4172	Belongs to the ABC transporter superfamily
Vag1382_43760	COG1505	serine-type exopeptidase activity
Vag1382_43770	COG0583	DNA-binding transcription factor activity
Vag1382_43780	COG1620	l-lactate permease
Vag1382_43790	COG1304	FMN binding
Vag1382_43810	COG0668	transmembrane transport
Vag1382_43830	COG1063	alcohol dehydrogenase
Vag1382_43840	COG0156	8-amino-7-oxononanoate synthase activity
Vag1382_43850	COG3300	MHYT domain
Vag1382_43850	COG5001	Diguanylate cyclase
Vag1382_43860	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Vag1382_43900	COG0745	RESPONSE REGULATOR receiver
Vag1382_43950	COG0346	lactoylglutathione lyase activity
Vag1382_44060	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
Vag1382_44140	COG1987	bacterial-type flagellum assembly
Vag1382_44160	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
Vag1382_44190	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
Vag1382_44230	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
Vag1382_44240	COG1516	flagellar protein fliS
Vag1382_44270	COG1580	Controls the rotational direction of flagella during chemotaxis
Vag1382_44280	COG1191	sigma factor activity
Vag1382_44290	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
Vag1382_44300	COG1360	Flagellar Motor Protein
Vag1382_44400	COG1882	Formate acetyltransferase
Vag1382_44410	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
Vag1382_44420	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
Vag1382_44440	COG0454	-acetyltransferase
Vag1382_44460	COG2814	Major facilitator Superfamily
Vag1382_44540	COG0628	permease
Vag1382_44550	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
Vag1382_44560	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
Vag1382_44580	COG4628	conserved protein (DUF2132)
Vag1382_44590	COG0583	DNA-binding transcription factor activity
Vag1382_44640	COG1686	Belongs to the peptidase S11 family
Vag1382_44690	COG0415	Belongs to the DNA photolyase family
Vag1382_44700	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
Vag1382_44710	COG3397	chitin binding
Vag1382_44720	COG4667	esterase of the alpha-beta hydrolase superfamily
Vag1382_44730	COG2095	MarC family integral membrane protein
Vag1382_44760	COG1596	polysaccharide export
Vag1382_44800	COG1301	dicarboxylic acid transport
Vag1382_44810	COG3339	Conserved Protein
Vag1382_44830	COG0700	Nucleoside recognition
Vag1382_44840	COG3366	ferrous iron transmembrane transporter activity
Vag1382_44860	COG0366	Alpha amylase catalytic
Vag1382_44870	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
Vag1382_44880	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
Vag1382_44890	COG1640	4-alpha-glucanotransferase
Vag1382_44900	COG0058	SHG alpha-glucan phosphorylase activity
Vag1382_44910	COG2909	trisaccharide binding
Vag1382_44940	COG1999	signal sequence binding
Vag1382_44950	COG1263	PTS System
Vag1382_44950	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
Vag1382_44960	COG1162	GTPase activity
Vag1382_44970	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
Vag1382_44980	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
Vag1382_45000	COG0531	amino acid
Vag1382_45010	COG1982	Orn Lys Arg decarboxylase major
Vag1382_45050	COG2356	endonuclease I
Vag1382_45090	COG4580	involved in the transport of maltose and maltodextrins
Vag1382_45170	COG0739	heme binding
Vag1382_45180	COG0612	Peptidase, M16
Vag1382_45190	COG0840	transmembrane signaling receptor activity
Vag1382_45200	COG1120	ATPase activity
Vag1382_45210	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Vag1382_45220	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Vag1382_45230	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
Vag1382_45240	COG4772	TonB-dependent receptor
Vag1382_45290	COG4264	IucA IucC family
Vag1382_45300	COG0019	diaminopimelate decarboxylase activity
Vag1382_45310	COG1653	transport
Vag1382_45330	COG0745	RESPONSE REGULATOR receiver
Vag1382_45400	COG0463	Glycosyl transferase, family 2
Vag1382_45430	COG1136	(ABC) transporter
Vag1382_45470	COG1764	response to oxidative stress
Vag1382_45480	COG1846	Transcriptional regulator
Vag1382_45500	COG3634	alkyl hydroperoxide reductase activity
Vag1382_45550	COG1595	DNA-templated transcription, initiation
Vag1382_45590	COG2258	MOSC domain
Vag1382_45640	COG2207	Transcriptional regulator
Vag1382_45660	COG1132	(ABC) transporter
Vag1382_45750	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
Vag1382_45800	COG0259	pyridoxamine-phosphate oxidase activity
Vag1382_45900	COG4166	transmembrane transport
Vag1382_45930	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
Vag1382_45940	COG1263	PTS System
Vag1382_45940	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
Vag1382_45950	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
Vag1382_45990	COG1444	tRNA N-acetyltransferase activity