locus-tag	class	description
FR729_00025	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FR729_00040	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
FR729_00050	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FR729_00080	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FR729_00095	COG3550	peptidyl-serine autophosphorylation
FR729_00145	COG3550	peptidyl-serine autophosphorylation
FR729_00230	COG0582	viral genome integration into host DNA
FR729_00295	COG0358	DNA primase activity
FR729_00300	COG1610	YqeY-like protein
FR729_00305	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FR729_00310	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FR729_00315	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FR729_00320	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FR729_00325	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FR729_00330	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FR729_00335	COG1968	undecaprenyl-diphosphatase activity
FR729_00345	COG3409	Peptidoglycan-binding domain 1 protein
FR729_00345	COG3267	Type II secretory pathway component ExeA
FR729_00355	COG0405	Gamma-glutamyltransferase
FR729_00360	COG4991	sh3 domain protein
FR729_00365	COG0306	phosphate transporter
FR729_00370	COG1392	Phosphate transport regulator
FR729_00375	COG3025	triphosphatase activity
FR729_00390	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
FR729_00395	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
FR729_00395	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
FR729_00400	COG1538	Outer membrane efflux protein
FR729_00405	COG0494	nUDIX hydrolase
FR729_00410	COG3151	Protein conserved in bacteria
FR729_00420	COG3150	esterase
FR729_00430	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FR729_00435	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FR729_00445	COG3105	Protein conserved in bacteria
FR729_00455	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
FR729_00470	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FR729_00475	COG0723	plastoquinol--plastocyanin reductase activity
FR729_00480	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FR729_00485	COG2857	Cytochrome c1
FR729_00490	COG0625	glutathione transferase activity
FR729_00495	COG2969	positive regulation of protein catabolic process
FR729_00500	COG2823	Periplasmic or secreted lipoprotein
FR729_00505	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
FR729_00520	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FR729_00540	COG3116	cell division
FR729_00545	COG0768	penicillin binding
FR729_00550	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FR729_00555	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FR729_00560	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FR729_00565	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FR729_00570	COG0772	Belongs to the SEDS family
FR729_00585	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FR729_00590	COG0849	cell division
FR729_00595	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FR729_00600	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
FR729_00610	COG0653	protein targeting
FR729_00615	COG0494	nUDIX hydrolase
FR729_00625	COG0505	Belongs to the CarA family
FR729_00630	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FR729_00650	COG0730	response to heat
FR729_00655	COG0583	DNA-binding transcription factor activity
FR729_00660	COG2860	membrane
FR729_00675	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FR729_00685	COG0493	'glutamate synthase
FR729_00690	COG0070	glutamate synthase
FR729_00690	COG0069	glutamate synthase activity
FR729_00690	COG0067	glutamate synthase
FR729_00700	COG0067	glutamate synthase
FR729_00700	COG0070	glutamate synthase
FR729_00700	COG0069	glutamate synthase activity
FR729_00705	COG1242	4 iron, 4 sulfur cluster binding
FR729_00710	COG4251	negative regulation of phosphorylation
FR729_00710	COG5001	Diguanylate cyclase
FR729_00710	COG3706	GGDEF domain
FR729_00710	COG2203	Gaf domain
FR729_00715	COG2198	Histidine kinase
FR729_00715	COG0784	Response regulator, receiver
FR729_00715	COG5002	protein histidine kinase activity
FR729_00725	COG0745	RESPONSE REGULATOR receiver
FR729_00740	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FR729_00760	COG0083	homoserine kinase activity
FR729_00765	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FR729_00775	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
FR729_00780	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
FR729_00790	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FR729_00805	COG1115	amino acid carrier protein
FR729_00810	COG3022	response to hydroperoxide
FR729_00815	COG0513	Belongs to the DEAD box helicase family
FR729_00820	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
FR729_00830	COG0716	FMN binding
FR729_00835	COG4974	Belongs to the 'phage' integrase family
FR729_00840	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FR729_00845	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FR729_00860	COG2204	response regulator
FR729_00870	COG0667	Aldo Keto reductase
FR729_00895	COG0730	response to heat
FR729_00905	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FR729_00915	COG1283	sodium-dependent phosphate transmembrane transporter activity
FR729_00920	COG0583	DNA-binding transcription factor activity
FR729_00925	COG0640	Transcriptional regulator
FR729_00930	COG0268	Binds directly to 16S ribosomal RNA
FR729_00935	COG0728	peptidoglycan biosynthetic process
FR729_00940	COG0196	riboflavin kinase activity
FR729_00955	COG1047	Peptidyl-prolyl cis-trans
FR729_00960	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FR729_00970	COG3279	Response regulator of the LytR AlgR family
FR729_00975	COG3275	phosphorelay sensor kinase activity
FR729_00980	COG1966	Carbon starvation protein
FR729_01000	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
FR729_01005	COG1472	Belongs to the glycosyl hydrolase 3 family
FR729_01010	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FR729_01015	COG0287	Prephenate dehydrogenase
FR729_01015	COG1605	Chorismate mutase
FR729_01020	COG0739	heme binding
FR729_01030	COG0488	(ABC) transporter
FR729_01040	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
FR729_01045	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
FR729_01050	COG0077	Prephenate dehydratase
FR729_01050	COG1605	Chorismate mutase
FR729_01055	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FR729_01060	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
FR729_01065	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FR729_01070	COG0564	pseudouridine synthase activity
FR729_01080	COG0542	response to heat
FR729_01140	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FR729_01150	COG2974	May be involved in recombination
FR729_01160	COG0745	RESPONSE REGULATOR receiver
FR729_01165	COG5002	protein histidine kinase activity
FR729_01175	COG0248	Ppx GppA phosphatase
FR729_01180	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FR729_01185	COG0573	inorganic phosphate transmembrane transporter activity
FR729_01190	COG0581	inorganic phosphate transmembrane transporter activity
FR729_01195	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FR729_01200	COG0704	Plays a role in the regulation of phosphate uptake
FR729_01210	COG3142	Participates in the control of copper homeostasis
FR729_01215	COG0450	alkyl hydroperoxide reductase
FR729_01220	COG0583	DNA-binding transcription factor activity
FR729_01225	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FR729_01235	COG0517	IMP dehydrogenase activity
FR729_01245	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FR729_01255	COG1862	Preprotein translocase
FR729_01260	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FR729_01265	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FR729_01270	COG0483	inositol monophosphate 1-phosphatase activity
FR729_01275	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
FR729_01285	COG1104	cysteine desulfurase activity
FR729_01290	COG0822	iron-sulfur transferase activity
FR729_01305	COG0443	Heat shock 70 kDa protein
FR729_01310	COG0633	Ferredoxin
FR729_01315	COG2975	iron-sulfur cluster assembly
FR729_01325	COG0105	UTP biosynthetic process
FR729_01340	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
FR729_01345	COG0124	histidyl-tRNA synthetase
FR729_01350	COG2976	Protein conserved in bacteria
FR729_01355	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FR729_01360	COG1160	GTP binding
FR729_01380	COG0517	IMP dehydrogenase activity
FR729_01380	COG0516	GMP reductase activity
FR729_01385	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FR729_01385	COG0519	Catalyzes the synthesis of GMP from XMP
FR729_01390	COG1757	Na H antiporter
FR729_01400	COG1584	GPR1 FUN34 yaaH family protein
FR729_01405	COG1115	amino acid carrier protein
FR729_01420	COG2873	o-acetylhomoserine
FR729_01425	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FR729_01445	COG3153	acetyltransferase
FR729_01445	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FR729_01450	COG0583	DNA-binding transcription factor activity
FR729_01475	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FR729_01480	COG2867	negative regulation of translational initiation
FR729_01485	COG2914	Belongs to the UPF0125 (RnfH) family
FR729_01490	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FR729_01500	COG0497	DNA recombination
FR729_01510	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FR729_01515	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FR729_01520	COG1301	dicarboxylic acid transport
FR729_01530	COG0484	heat shock protein binding
FR729_01560	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
FR729_01575	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
FR729_01580	COG0047	phosphoribosylformylglycinamidine synthase activity
FR729_01580	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FR729_01610	COG2195	Cleaves the N-terminal amino acid of tripeptides
FR729_01615	COG2252	PERMEase
FR729_01620	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
FR729_01635	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FR729_01640	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FR729_01645	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FR729_01650	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FR729_01650	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FR729_01665	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FR729_01675	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
FR729_01680	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FR729_01690	COG0142	geranyltranstransferase activity
FR729_01695	COG1722	exodeoxyribonuclease VII activity
FR729_01700	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FR729_01710	COG0301	tRNA thio-modification
FR729_01710	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FR729_01715	COG0583	DNA-binding transcription factor activity
FR729_01725	COG2363	Small membrane protein
FR729_01735	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FR729_01740	COG1611	Belongs to the LOG family
FR729_01755	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FR729_01755	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FR729_01765	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
FR729_01770	COG1464	Belongs to the NlpA lipoprotein family
FR729_01775	COG2011	ABC-type metal ion transport system permease component
FR729_01780	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FR729_01785	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FR729_01795	COG1263	PTS System
FR729_01795	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FR729_01800	COG0366	Alpha amylase catalytic
FR729_01815	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FR729_01820	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FR729_01825	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FR729_01830	COG0321	lipoyl(octanoyl) transferase activity
FR729_01840	COG1686	Belongs to the peptidase S11 family
FR729_01845	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FR729_01850	COG0772	Belongs to the SEDS family
FR729_01855	COG0768	penicillin binding
FR729_01860	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FR729_01865	COG0799	negative regulation of ribosome biogenesis
FR729_01870	COG1466	dna polymerase III delta subunit
FR729_01875	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
FR729_01880	COG0495	leucyl-tRNA aminoacylation
FR729_01885	COG2888	peptidyl-tyrosine sulfation
FR729_01890	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FR729_01895	COG4535	Mg2 and Co2 transporter CorC
FR729_01900	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FR729_01905	COG1702	phosphate starvation-inducible protein PhoH
FR729_01910	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FR729_01920	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FR729_02030	COG0012	GTP binding
FR729_02035	COG0193	aminoacyl-tRNA hydrolase activity
FR729_02040	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FR729_02045	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FR729_02050	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
FR729_02055	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
FR729_02065	COG2890	protein-(glutamine-N5) methyltransferase activity
FR729_02070	COG3094	Invasion gene expression up-regulator, SirB
FR729_02075	COG2912	Transglutaminase-like superfamily
FR729_02080	COG2877	3-deoxy-8-phosphooctulonate synthase activity
FR729_02085	COG0737	Belongs to the 5'-nucleotidase family
FR729_02090	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FR729_02095	COG1187	pseudouridine synthase activity
FR729_02100	COG2840	Smr protein MutS2
FR729_02140	COG2217	Heavy metal translocating P-type atpase
FR729_02140	COG2608	mercury ion transmembrane transporter activity
FR729_02160	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
FR729_02215	COG0835	chemotaxis
FR729_02215	COG0784	Response regulator, receiver
FR729_02220	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FR729_02225	COG1815	bacterial-type flagellum-dependent cell motility
FR729_02230	COG1558	bacterial-type flagellum-dependent cell motility
FR729_02240	COG1749	Flagellar hook protein flgE
FR729_02245	COG4787	bacterial-type flagellum-dependent cell motility
FR729_02255	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
FR729_02260	COG1706	bacterial-type flagellum-dependent cell motility
FR729_02265	COG3951	Flagellar rod assembly protein muramidase FlgJ
FR729_02265	COG1705	Flagellar rod assembly protein muramidase FlgJ
FR729_02275	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FR729_02280	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FR729_02290	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FR729_02295	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FR729_02300	COG2190	(PTS) system
FR729_02305	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FR729_02310	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FR729_02320	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FR729_02325	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
FR729_02330	COG3115	cell septum assembly
FR729_02335	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FR729_02360	COG0330	HflC and HflK could
FR729_02365	COG3118	belongs to the thioredoxin family
FR729_02375	COG0300	oxidoreductase activity
FR729_02380	COG1090	epimerase
FR729_02410	COG0622	Phosphoesterase
FR729_02430	COG3710	Transcriptional regulator
FR729_02435	COG0326	Molecular chaperone. Has ATPase activity
FR729_02445	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FR729_02450	COG3104	oligopeptide transport
FR729_02455	COG0250	Participates in transcription elongation, termination and antitermination
FR729_02460	COG0367	asparagine synthase
FR729_02465	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FR729_02465	COG4651	solute:proton antiporter activity
FR729_02470	COG1940	carbohydrate kinase activity
FR729_02470	COG1846	Transcriptional regulator
FR729_02475	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FR729_02485	COG2190	(PTS) system
FR729_02485	COG1263	PTS System
FR729_02485	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FR729_02490	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FR729_02495	COG0735	belongs to the Fur family
FR729_02505	COG0716	FMN binding
FR729_02515	COG0596	Alpha beta hydrolase
FR729_02520	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
FR729_02525	COG0033	Phosphoglucomutase
FR729_02535	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FR729_02550	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
FR729_02555	COG1053	succinate dehydrogenase
FR729_02560	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FR729_02565	COG0567	Dehydrogenase, E1 component
FR729_02570	COG0508	dehydrogenase complex catalyzes the overall conversion of
FR729_02575	COG0045	succinate-CoA ligase (ADP-forming) activity
FR729_02585	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FR729_02590	COG1121	(ABC) transporter
FR729_02595	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
FR729_02600	COG4977	sequence-specific DNA binding
FR729_02605	COG1918	ferrous iron import across plasma membrane
FR729_02625	COG0018	arginyl-trna synthetase
FR729_02635	COG3102	Protein conserved in bacteria
FR729_02650	COG0788	formyltetrahydrofolate deformylase activity
FR729_02655	COG1199	ATP-dependent helicase activity
FR729_02660	COG1214	PFAM Peptidase M22, glycoprotease
FR729_02670	COG3065	identical protein binding
FR729_02675	COG2267	carboxylic ester hydrolase activity
FR729_02680	COG0318	PFAM AMP-dependent synthetase and ligase
FR729_02685	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
FR729_02690	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
FR729_02695	COG2894	cell division
FR729_02700	COG0850	regulation of cytokinetic process
FR729_02705	COG3100	YcgL domain-containing protein
FR729_02710	COG2951	lytic endotransglycosylase activity
FR729_02720	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FR729_02725	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FR729_02735	COG2226	methyltransferase
FR729_02745	COG1028	Short-chain dehydrogenase reductase Sdr
FR729_02755	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FR729_02780	COG2986	histidine ammonia-lyase
FR729_02785	COG1216	Glycosyl transferase, family 2
FR729_02790	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FR729_02805	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FR729_02810	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FR729_02845	COG0513	Belongs to the DEAD box helicase family
FR729_02850	COG0569	domain protein
FR729_02855	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FR729_02870	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
FR729_02875	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FR729_02880	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FR729_02885	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FR729_02910	COG0544	peptidyl-prolyl cis-trans isomerase activity
FR729_02920	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FR729_02925	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FR729_02930	COG0776	regulation of translation
FR729_02935	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FR729_02940	COG1555	photosystem II stabilization
FR729_02955	COG0232	Belongs to the dGTPase family. Type 2 subfamily
FR729_02960	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
FR729_02965	COG0436	Aminotransferase
FR729_02970	COG1169	isochorismate synthase
FR729_02975	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
FR729_02985	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FR729_03005	COG2855	membrane
FR729_03010	COG0477	Major facilitator Superfamily
FR729_03055	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FR729_03060	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FR729_03080	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FR729_03085	COG1522	sequence-specific DNA binding
FR729_03095	COG1946	Acyl-CoA thioesterase
FR729_03100	COG3126	Type III secretion system lipoprotein chaperone (YscW)
FR729_03115	COG3706	GGDEF domain
FR729_03125	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FR729_03130	COG0516	GMP reductase activity
FR729_03130	COG0517	IMP dehydrogenase activity
FR729_03155	COG0537	adenosine 5'-monophosphoramidase activity
FR729_03180	COG3150	esterase
FR729_03185	COG1252	NADH dehydrogenase
FR729_03200	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FR729_03210	COG4591	ABC-type transport system involved in lipoprotein release permease component
FR729_03215	COG1136	(ABC) transporter
FR729_03220	COG4591	ABC-type transport system involved in lipoprotein release permease component
FR729_03230	COG0658	competence protein
FR729_03230	COG2333	competence protein COMEC
FR729_03235	COG1132	(ABC) transporter
FR729_03255	COG2719	SpoVR family
FR729_03260	COG2718	Belongs to the UPF0229 family
FR729_03265	COG2766	serine protein kinase
FR729_03275	COG3013	Belongs to the UPF0304 family
FR729_03285	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FR729_03295	COG1882	Formate acetyltransferase
FR729_03340	COG0708	Exodeoxyribonuclease III
FR729_03350	COG3923	Primosomal replication protein n
FR729_03355	COG0730	response to heat
FR729_03360	COG1199	ATP-dependent helicase activity
FR729_03365	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FR729_03370	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
FR729_03375	COG1187	pseudouridine synthase activity
FR729_03385	COG1278	Cold shock
FR729_03390	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FR729_03395	COG0542	response to heat
FR729_03400	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FR729_03405	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
FR729_03410	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
FR729_03430	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FR729_03435	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FR729_03440	COG0297	glycogen (starch) synthase activity
FR729_03460	COG3070	regulator of competence-specific genes
FR729_03465	COG1609	Transcriptional regulator
FR729_03470	COG3381	protein complex oligomerization
FR729_03475	COG0745	RESPONSE REGULATOR receiver
FR729_03480	COG1434	Gram-negative-bacterium-type cell wall biogenesis
FR729_03485	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FR729_03490	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
FR729_03495	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
FR729_03500	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
FR729_03520	COG0189	ligase activity
FR729_03520	COG4067	protein conserved in archaea
FR729_03530	COG0500	methyltransferase
FR729_03540	COG1801	Protein of unknown function DUF72
FR729_03550	COG0217	transcriptional regulatory protein
FR729_03555	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
FR729_03560	COG0632	four-way junction helicase activity
FR729_03565	COG2255	four-way junction helicase activity
FR729_03570	COG1271	oxidase subunit
FR729_03575	COG1294	oxidase, subunit
FR729_03580	COG4890	Cyd operon protein YbgT
FR729_03590	COG0824	Thioesterase
FR729_03595	COG0811	peptide transport
FR729_03610	COG0823	Involved in the tonB-independent uptake of proteins
FR729_03615	COG2885	chlorophyll binding
FR729_03620	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
FR729_03625	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FR729_03635	COG3766	membrane
FR729_03645	COG0754	glutathionylspermidine amidase activity
FR729_03655	COG0784	Response regulator, receiver
FR729_03655	COG5002	protein histidine kinase activity
FR729_03670	COG1294	oxidase, subunit
FR729_03675	COG1271	oxidase subunit
FR729_03695	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FR729_03700	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FR729_03725	COG3568	Endonuclease Exonuclease Phosphatase
FR729_03750	COG0583	DNA-binding transcription factor activity
FR729_03760	COG0686	Belongs to the AlaDH PNT family
FR729_03770	COG1674	ftsk spoiiie
FR729_03780	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FR729_03790	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FR729_03815	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
FR729_03835	COG0300	oxidoreductase activity
FR729_03850	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FR729_03860	COG2268	Band 7 protein
FR729_03870	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FR729_03875	COG2915	High frequency lysogenization protein hflD homolog
FR729_03890	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FR729_03900	COG1757	Na H antiporter
FR729_03915	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FR729_03925	COG0131	Imidazoleglycerol-phosphate dehydratase
FR729_03925	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FR729_03930	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FR729_03935	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FR729_03945	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FR729_03945	COG0140	phosphoribosyl-ATP diphosphatase activity
FR729_03950	COG3012	SEC-C Motif Domain Protein
FR729_03955	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
FR729_03960	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FR729_03965	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FR729_03970	COG0215	cysteine-tRNA ligase activity
FR729_03975	COG1435	thymidine kinase activity
FR729_04005	COG2116	formate transmembrane transporter activity
FR729_04015	COG0390	transport system, permease component
FR729_04020	COG4459	periplasmic nitrate reductase
FR729_04025	COG3005	denitrification pathway
FR729_04030	COG0243	molybdopterin cofactor binding
FR729_04045	COG1227	inorganic diphosphatase activity
FR729_04055	COG4172	Belongs to the ABC transporter superfamily
FR729_04065	COG4171	peptide transport system, permease
FR729_04080	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
FR729_04085	COG1842	Phage shock protein A
FR729_04095	COG1983	PspC domain protein
FR729_04115	COG2818	Glycosylase
FR729_04120	COG5380	lipid catabolic process
FR729_04125	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
FR729_04130	COG0626	cystathionine gamma-synthase activity
FR729_04140	COG0733	neurotransmitter:sodium symporter activity
FR729_04145	COG0564	pseudouridine synthase activity
FR729_04155	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FR729_04160	COG1151	hydroxylamine reductase activity
FR729_04165	COG3604	Transcriptional regulator
FR729_04180	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FR729_04185	COG4136	ATPase activity
FR729_04190	COG4135	transport system, permease component
FR729_04195	COG4134	Bacterial extracellular solute-binding protein
FR729_04205	COG3313	Fe-S protein
FR729_04230	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FR729_04235	COG2205	protein histidine kinase activity
FR729_04240	COG0745	RESPONSE REGULATOR receiver
FR729_04250	COG1061	Type III restriction enzyme res subunit
FR729_04255	COG1187	pseudouridine synthase activity
FR729_04265	COG2814	Major facilitator Superfamily
FR729_04275	COG0702	epimerase
FR729_04280	COG0534	Mate efflux family protein
FR729_04300	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FR729_04310	COG1960	acyl-CoA dehydrogenase activity
FR729_04315	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FR729_04320	COG3273	potassium ion transport
FR729_04320	COG2985	domain, Protein
FR729_04325	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FR729_04340	COG1737	Transcriptional regulator
FR729_04345	COG0076	glutamate decarboxylase activity
FR729_04355	COG2431	L-lysine efflux transmembrane transporter activity
FR729_04375	COG3070	regulator of competence-specific genes
FR729_04390	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FR729_04390	COG4191	Histidine kinase
FR729_04400	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
FR729_04410	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FR729_04415	COG4988	ABC transporter
FR729_04420	COG0492	ferredoxin-NADP+ reductase activity
FR729_04445	COG0471	metal ion transport
FR729_04450	COG2949	membrane
FR729_04455	COG0281	malic enzyme
FR729_04460	COG1643	Atp-dependent helicase
FR729_04475	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FR729_04510	COG0277	FAD linked oxidase domain protein
FR729_04510	COG0247	lactate metabolic process
FR729_04525	COG2986	histidine ammonia-lyase
FR729_04530	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
FR729_04535	COG0010	Belongs to the arginase family
FR729_04540	COG1228	amidohydrolase
FR729_04545	COG2188	Transcriptional regulator
FR729_04560	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FR729_04570	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FR729_04580	COG0393	Putative heavy-metal-binding
FR729_04615	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FR729_04620	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FR729_04620	COG0072	phenylalanine-tRNA ligase activity
FR729_04630	COG0776	regulation of translation
FR729_04640	COG0500	methyltransferase
FR729_04645	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
FR729_04650	COG0295	cytidine deaminase activity
FR729_04655	COG1346	cytolysis
FR729_04660	COG1380	Effector of murein hydrolase LrgA
FR729_04665	COG2925	Exonuclease
FR729_04675	COG0702	epimerase
FR729_04680	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
FR729_04685	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
FR729_04705	COG2988	succinylglutamate desuccinylase activity
FR729_04710	COG4139	cobalamin transport
FR729_04715	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
FR729_04735	COG0583	DNA-binding transcription factor activity
FR729_04745	COG1451	nucleotide metabolic process
FR729_04750	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
FR729_04780	COG3938	Belongs to the proline racemase family
FR729_04795	COG2423	ornithine cyclodeaminase activity
FR729_04800	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FR729_04805	COG3842	ATPase activity
FR729_04815	COG1177	transmembrane transport
FR729_04825	COG3291	Pkd domain containing protein
FR729_04845	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FR729_04850	COG0601	transmembrane transport
FR729_04860	COG2195	Cleaves the N-terminal amino acid of tripeptides
FR729_04870	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
FR729_04880	COG0625	glutathione transferase activity
FR729_04930	COG3755	Protein conserved in bacteria
FR729_04955	COG1742	UPF0060 membrane protein
FR729_04970	COG1757	Na H antiporter
FR729_04975	COG0174	glutamine synthetase
FR729_04985	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
FR729_04990	COG1917	Cupin 2, conserved barrel domain protein
FR729_04990	COG1396	sequence-specific DNA binding
FR729_04995	COG1012	belongs to the aldehyde dehydrogenase family
FR729_05000	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FR729_05010	COG2957	Belongs to the agmatine deiminase family
FR729_05015	COG1012	belongs to the aldehyde dehydrogenase family
FR729_05020	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FR729_05025	COG2200	EAL domain
FR729_05035	COG1846	Transcriptional regulator
FR729_05040	COG2315	Protein conserved in bacteria
FR729_05080	COG3063	Type IV pilus biogenesis stability protein PilW
FR729_05085	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
FR729_05100	COG1560	Kdo2-lipid A biosynthetic process
FR729_05105	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
FR729_05110	COG1280	lysine exporter protein (LysE YggA)
FR729_05120	COG1115	amino acid carrier protein
FR729_05145	COG1368	sulfuric ester hydrolase activity
FR729_05150	COG2113	Glycine betaine
FR729_05155	COG4176	ABC-type proline glycine betaine transport system permease component
FR729_05160	COG4175	Glycine betaine
FR729_05175	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FR729_05180	COG0456	acetyltransferase
FR729_05185	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FR729_05190	COG0662	Cupin 2, conserved barrel domain protein
FR729_05195	COG0527	aspartate kinase activity
FR729_05205	COG3119	arylsulfatase activity
FR729_05220	COG0641	radical SAM
FR729_05235	COG3119	arylsulfatase activity
FR729_05260	COG1538	Outer membrane efflux protein
FR729_05275	COG1349	DNA-binding transcription factor activity
FR729_05280	COG0673	inositol 2-dehydrogenase activity
FR729_05285	COG4702	Belongs to the UPF0303 family
FR729_05310	COG0471	metal ion transport
FR729_05325	COG5001	Diguanylate cyclase
FR729_05325	COG3300	MHYT domain
FR729_05340	COG1328	CTP reductase activity
FR729_05345	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FR729_05355	COG0861	Integral membrane protein TerC family
FR729_05365	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FR729_05375	COG0814	amino acid
FR729_05390	COG1120	ATPase activity
FR729_05395	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FR729_05405	COG4774	siderophore transport
FR729_05415	COG1132	(ABC) transporter
FR729_05420	COG1132	(ABC) transporter
FR729_05435	COG0583	DNA-binding transcription factor activity
FR729_05460	COG0443	Heat shock 70 kDa protein
FR729_05465	COG0443	Heat shock 70 kDa protein
FR729_05510	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FR729_05515	COG1643	Atp-dependent helicase
FR729_05530	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FR729_05540	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FR729_05545	COG1215	transferase activity, transferring glycosyl groups
FR729_05550	COG0438	transferase activity, transferring glycosyl groups
FR729_05580	COG0438	transferase activity, transferring glycosyl groups
FR729_05585	COG0297	glycogen (starch) synthase activity
FR729_05590	COG2204	response regulator
FR729_05620	COG1793	dna ligase
FR729_05630	COG0534	Mate efflux family protein
FR729_05635	COG0307	riboflavin synthase, alpha
FR729_05645	COG3001	Fructosamine kinase
FR729_05655	COG3706	GGDEF domain
FR729_05665	COG0791	NLP P60 protein
FR729_05705	COG1940	carbohydrate kinase activity
FR729_05715	COG0303	'Molybdopterin
FR729_05720	COG0746	molybdenum cofactor guanylyltransferase activity
FR729_05725	COG3842	ATPase activity
FR729_05740	COG2204	response regulator
FR729_05745	COG4191	Histidine kinase
FR729_05755	COG0488	(ABC) transporter
FR729_05760	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FR729_05780	COG3381	protein complex oligomerization
FR729_05790	COG3383	formate dehydrogenase (NAD+) activity
FR729_05790	COG0243	molybdopterin cofactor binding
FR729_05795	COG0437	4 iron, 4 sulfur cluster binding
FR729_05820	COG0004	ammonium transporteR
FR729_05825	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FR729_05835	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FR729_05845	COG1177	transmembrane transport
FR729_05855	COG3842	ATPase activity
FR729_05880	COG0589	response to stress
FR729_05885	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FR729_05900	COG2217	Heavy metal translocating P-type atpase
FR729_05910	COG2010	Cytochrome c
FR729_05925	COG3278	Belongs to the heme-copper respiratory oxidase family
FR729_05940	COG0784	Response regulator, receiver
FR729_05940	COG2205	protein histidine kinase activity
FR729_05955	COG3120	sequence-specific DNA binding
FR729_05960	COG1067	ATP-dependent peptidase activity
FR729_05965	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FR729_05990	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FR729_05990	COG0116	Belongs to the methyltransferase superfamily
FR729_06000	COG0167	dihydroorotate dehydrogenase activity
FR729_06005	COG2902	Dehydrogenase
FR729_06015	COG0308	aminopeptidase N
FR729_06030	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
FR729_06035	COG1956	GAF domain-containing protein
FR729_06040	COG1132	(ABC) transporter
FR729_06045	COG2995	paraquat-inducible protein a
FR729_06050	COG3008	intermembrane lipid transfer
FR729_06075	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FR729_06080	COG1666	GTP binding
FR729_06095	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FR729_06100	COG4597	amino acid ABC transporter
FR729_06105	COG0765	amino acid transport
FR729_06110	COG1126	abc transporter atp-binding protein
FR729_06115	COG0670	Belongs to the BI1 family
FR729_06125	COG2920	part of a sulfur-relay system
FR729_06130	COG1254	Belongs to the acylphosphatase family
FR729_06185	COG2203	Gaf domain
FR729_06185	COG2199	diguanylate cyclase activity
FR729_06190	COG1414	Transcriptional regulator
FR729_06200	COG0656	L-ascorbic acid biosynthetic process
FR729_06205	COG0583	DNA-binding transcription factor activity
FR729_06215	COG0583	DNA-binding transcription factor activity
FR729_06220	COG2814	Major facilitator Superfamily
FR729_06240	COG1335	isochorismatase
FR729_06245	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FR729_06260	COG1410	methionine synthase
FR729_06260	COG0646	methionine synthase
FR729_06265	COG1126	abc transporter atp-binding protein
FR729_06270	COG0765	amino acid transport
FR729_06275	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FR729_06290	COG0583	DNA-binding transcription factor activity
FR729_06305	COG0583	DNA-binding transcription factor activity
FR729_06315	COG0583	DNA-binding transcription factor activity
FR729_06330	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FR729_06335	COG0602	queuosine metabolic process
FR729_06340	COG0561	phosphatase activity
FR729_06365	COG2828	Protein conserved in bacteria
FR729_06375	COG0372	Belongs to the citrate synthase family
FR729_06380	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
FR729_06415	COG0730	response to heat
FR729_06420	COG2358	TRAP transporter, solute receptor (TAXI family
FR729_06440	COG0457	Tetratricopeptide repeat
FR729_06510	COG4790	Type iii secretion
FR729_06515	COG4794	Type iii secretion
FR729_06520	COG4791	protein targeting
FR729_06525	COG4792	protein secretion
FR729_06530	COG2207	Transcriptional regulator
FR729_06560	COG3177	Filamentation induced by cAMP protein fic
FR729_06580	COG4669	(LipO)protein
FR729_06650	COG1012	belongs to the aldehyde dehydrogenase family
FR729_06655	COG3284	Transcriptional regulator
FR729_06670	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FR729_06675	COG0363	glucosamine-6-phosphate deaminase activity
FR729_06680	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FR729_06685	COG2207	Transcriptional regulator
FR729_06695	COG4565	transcriptional regulatory protein
FR729_06700	COG3290	protein histidine kinase activity
FR729_06715	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FR729_06730	COG0583	DNA-binding transcription factor activity
FR729_06745	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
FR729_06755	COG2985	domain, Protein
FR729_06780	COG2272	Belongs to the type-B carboxylesterase lipase family
FR729_06785	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FR729_06790	COG0729	surface antigen
FR729_06800	COG1280	lysine exporter protein (LysE YggA)
FR729_06805	COG1280	lysine exporter protein (LysE YggA)
FR729_06810	COG5507	3-demethylubiquinone-9 3-methyltransferase
FR729_06830	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FR729_06835	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FR729_06840	COG0110	maltose O-acetyltransferase activity
FR729_07010	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
FR729_07020	COG2801	Transposase and inactivated derivatives
FR729_07065	COG2226	methyltransferase
FR729_07325	COG2026	Addiction module toxin, RelE StbE family
FR729_07360	COG2801	Transposase and inactivated derivatives
FR729_07590	COG2801	Transposase and inactivated derivatives
FR729_07820	COG0625	glutathione transferase activity
FR729_07870	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FR729_07880	COG3768	UPF0283 membrane protein
FR729_07885	COG3106	COG3106 Predicted ATPase
FR729_07905	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FR729_07910	COG0784	Response regulator, receiver
FR729_07910	COG2205	protein histidine kinase activity
FR729_07920	COG0494	nUDIX hydrolase
FR729_07925	COG0814	amino acid
FR729_07930	COG1760	l-serine dehydratase
FR729_07935	COG2200	EAL domain
FR729_07945	COG0720	synthase
FR729_07950	COG0840	transmembrane signaling receptor activity
FR729_07955	COG0017	Asparaginyl-tRNA synthetase
FR729_07965	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FR729_07980	COG1448	Aminotransferase
FR729_08000	COG0840	transmembrane signaling receptor activity
FR729_08005	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FR729_08035	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FR729_08050	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FR729_08055	COG3108	Peptidase M15
FR729_08060	COG2989	Protein conserved in bacteria
FR729_08085	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FR729_08095	COG4235	cytochrome complex assembly
FR729_08095	COG3088	subunit of a heme lyase
FR729_08105	COG1138	Cytochrome C-type biogenesis protein
FR729_08110	COG3301	Polysulphide reductase, NrfD
FR729_08115	COG0437	4 iron, 4 sulfur cluster binding
FR729_08125	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
FR729_08145	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FR729_08155	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FR729_08185	COG0019	diaminopimelate decarboxylase activity
FR729_08225	COG0322	excinuclease ABC activity
FR729_08230	COG2197	response regulator
FR729_08235	COG0417	DNA replication proofreading
FR729_08255	COG1187	pseudouridine synthase activity
FR729_08265	COG0009	L-threonylcarbamoyladenylate synthase
FR729_08270	COG0613	PHP domain protein
FR729_08280	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FR729_08285	COG0512	Glutamine amidotransferase of anthranilate synthase
FR729_08295	COG0135	phosphoribosylanthranilate isomerase activity
FR729_08295	COG0134	indole-3-glycerol-phosphate synthase activity
FR729_08305	COG0159	tryptophan synthase activity
FR729_08310	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FR729_08315	COG0318	PFAM AMP-dependent synthetase and ligase
FR729_08325	COG1301	dicarboxylic acid transport
FR729_08345	COG2917	probably involved in intracellular septation
FR729_08355	COG2350	Protein conserved in bacteria
FR729_08365	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FR729_08370	COG0583	DNA-binding transcription factor activity
FR729_08385	COG5001	Diguanylate cyclase
FR729_08390	COG1032	radical SAM domain protein
FR729_08410	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
FR729_08415	COG0463	Glycosyl transferase, family 2
FR729_08420	COG0745	RESPONSE REGULATOR receiver
FR729_08425	COG3850	Histidine kinase
FR729_08425	COG5002	protein histidine kinase activity
FR729_08475	COG1335	isochorismatase
FR729_08480	COG1136	(ABC) transporter
FR729_08480	COG0577	efflux transmembrane transporter activity
FR729_08485	COG1136	(ABC) transporter
FR729_08485	COG0577	efflux transmembrane transporter activity
FR729_08490	COG1136	(ABC) transporter
FR729_08490	COG0577	efflux transmembrane transporter activity
FR729_08500	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FR729_08525	COG3118	belongs to the thioredoxin family
FR729_08530	COG4232	protein-disulfide reductase activity
FR729_08565	COG2863	cytochrome
FR729_08570	COG3258	Cytochrome c
FR729_08575	COG2995	paraquat-inducible protein a
FR729_08580	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FR729_08580	COG3008	intermembrane lipid transfer
FR729_08600	COG4166	transmembrane transport
FR729_08610	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
FR729_08615	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
FR729_08625	COG0539	negative regulation of cytoplasmic translation
FR729_08630	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FR729_08635	COG0616	signal peptide processing
FR729_08640	COG1028	Short-chain dehydrogenase reductase Sdr
FR729_08655	COG0587	DNA-directed DNA polymerase activity
FR729_08660	COG0835	chemotaxis
FR729_08660	COG0784	Response regulator, receiver
FR729_08665	COG1940	carbohydrate kinase activity
FR729_08670	COG0469	pyruvate kinase activity
FR729_08675	COG4667	esterase of the alpha-beta hydrolase superfamily
FR729_08690	COG0733	neurotransmitter:sodium symporter activity
FR729_08705	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FR729_08705	COG1263	PTS System
FR729_08710	COG0084	hydrolase, TatD family'
FR729_08715	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FR729_08720	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FR729_08725	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FR729_08755	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FR729_08760	COG0416	fatty acid biosynthetic process
FR729_08770	COG1399	metal-binding, possibly nucleic acid-binding protein
FR729_08775	COG0424	maF-like protein
FR729_08780	COG0564	pseudouridine synthase activity
FR729_08790	COG1530	ribonuclease E activity
FR729_08800	COG0659	secondary active sulfate transmembrane transporter activity
FR729_08805	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FR729_08810	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
FR729_08820	COG0572	uridine kinase
FR729_08830	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FR729_08830	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FR729_08840	COG2186	Transcriptional regulator
FR729_08845	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FR729_08850	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
FR729_08855	COG3318	Belongs to the UPF0149 family
FR729_08855	COG3012	SEC-C Motif Domain Protein
FR729_08860	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FR729_08865	COG3706	GGDEF domain
FR729_08870	COG0366	Alpha amylase catalytic
FR729_08875	COG1122	ATPase activity
FR729_08880	COG4120	Belongs to the binding-protein-dependent transport system permease family
FR729_08890	COG3092	negative regulation of chromosome organization
FR729_08895	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FR729_08900	COG0280	phosphate acetyltransferase
FR729_08900	COG0857	belongs to the CobB CobQ family
FR729_08910	COG0435	Glutathione S-transferase
FR729_08920	COG0444	Belongs to the ABC transporter superfamily
FR729_08925	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FR729_08930	COG0601	transmembrane transport
FR729_08940	COG0314	molybdopterin synthase activity
FR729_08945	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
FR729_08950	COG0315	cyclic pyranopterin monophosphate synthase activity
FR729_08955	COG0521	Mo-molybdopterin cofactor biosynthetic process
FR729_08960	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FR729_08965	COG0391	Required for morphogenesis under gluconeogenic growth conditions
FR729_08970	COG2198	Histidine kinase
FR729_08975	COG2204	response regulator
FR729_08980	COG0556	nucleotide-excision repair
FR729_08990	COG1882	Formate acetyltransferase
FR729_08995	COG4657	Part of a membrane complex involved in electron transport
FR729_09000	COG2878	Part of a membrane complex involved in electron transport
FR729_09005	COG4656	Part of a membrane complex involved in electron transport
FR729_09010	COG4658	electron transport chain
FR729_09015	COG4659	FMN binding
FR729_09020	COG4660	Part of a membrane complex involved in electron transport
FR729_09025	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FR729_09030	COG0346	lactoylglutathione lyase activity
FR729_09040	COG2885	chlorophyll binding
FR729_09050	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FR729_09055	COG2056	Na+-H+ antiporter family
FR729_09065	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FR729_09085	COG1454	alcohol dehydrogenase
FR729_09085	COG1012	belongs to the aldehyde dehydrogenase family
FR729_09090	COG2095	MarC family integral membrane protein
FR729_09095	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FR729_09100	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FR729_09105	COG1757	Na H antiporter
FR729_09120	COG3081	Nucleoid-associated protein
FR729_09125	COG3082	Protein of unknown function (DUF1414)
FR729_09140	COG0123	including yeast histone deacetylase and acetoin utilization protein
FR729_09155	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FR729_09160	COG0778	Nitroreductase
FR729_09170	COG0446	pyridine nucleotide-disulphide oxidoreductase
FR729_09170	COG1902	pentaerythritol trinitrate reductase activity
FR729_09175	COG0616	signal peptide processing
FR729_09180	COG0252	asparaginase activity
FR729_09185	COG3139	Protein of unknown function (DUF1315)
FR729_09195	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FR729_09200	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FR729_09215	COG2226	methyltransferase
FR729_09235	COG1785	Belongs to the alkaline phosphatase family
FR729_09245	COG0346	lactoylglutathione lyase activity
FR729_09250	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
FR729_09255	COG0668	transmembrane transport
FR729_09260	COG2983	Belongs to the UPF0260 family
FR729_09265	COG2261	transglycosylase associated protein
FR729_09275	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FR729_09280	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FR729_09295	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FR729_09300	COG2832	Protein of unknown function (DUF454)
FR729_09310	COG0745	RESPONSE REGULATOR receiver
FR729_09315	COG0583	DNA-binding transcription factor activity
FR729_09320	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FR729_09325	COG1286	toxin biosynthetic process
FR729_09330	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
FR729_09335	COG0285	dihydrofolate synthase activity
FR729_09340	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FR729_09350	COG0101	tRNA pseudouridine synthase activity
FR729_09360	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FR729_09365	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FR729_09375	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FR729_09380	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FR729_09380	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
FR729_09385	COG0431	NADPH-dependent FMN reductase
FR729_09400	COG3101	peptidyl-lysine hydroxylation
FR729_09410	COG2860	membrane
FR729_09415	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FR729_09420	COG2890	protein-(glutamine-N5) methyltransferase activity
FR729_09425	COG2840	Smr protein MutS2
FR729_09430	COG2062	phosphohistidine phosphatase, SixA
FR729_09445	COG1250	3-hydroxyacyl-CoA dehydrogenase
FR729_09445	COG1024	Enoyl-CoA hydratase
FR729_09450	COG0183	Belongs to the thiolase family
FR729_09475	COG2067	long-chain fatty acid transport protein
FR729_09485	COG4235	cytochrome complex assembly
FR729_09485	COG3088	subunit of a heme lyase
FR729_09495	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FR729_09500	COG1138	Cytochrome C-type biogenesis protein
FR729_09505	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
FR729_09510	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FR729_09515	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FR729_09520	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FR729_09525	COG4133	protoheme IX ABC transporter activity
FR729_09535	COG0835	chemotaxis
FR729_09545	COG1192	Involved in chromosome partitioning
FR729_09550	COG2201	protein-glutamate methylesterase activity
FR729_09555	COG0643	Histidine kinase
FR729_09555	COG0784	Response regulator, receiver
FR729_09555	COG2198	Histidine kinase
FR729_09560	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
FR729_09600	COG1987	bacterial-type flagellum assembly
FR729_09655	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FR729_09665	COG1677	Flagellar hook-basal body complex protein FliE
FR729_09675	COG4191	Histidine kinase
FR729_09685	COG1516	flagellar protein fliS
FR729_09695	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
FR729_09700	COG1334	flagellar protein FlaG
FR729_09705	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FR729_09710	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FR729_09720	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FR729_09725	COG2837	iron assimilation
FR729_09750	COG1393	Belongs to the ArsC family
FR729_09755	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FR729_09775	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FR729_09785	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FR729_09800	COG4783	chaperone-mediated protein folding
FR729_09805	COG1393	Belongs to the ArsC family
FR729_09825	COG2233	PERMEase
FR729_09835	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FR729_09840	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FR729_09845	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FR729_09850	COG0121	glutamine amidotransferase
FR729_09855	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
FR729_09860	COG1960	acyl-CoA dehydrogenase activity
FR729_09895	COG0328	RNA-DNA hybrid ribonuclease activity
FR729_09900	COG2226	methyltransferase
FR729_09905	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FR729_09910	COG0741	lytic transglycosylase activity
FR729_09910	COG1388	LysM domain
FR729_09920	COG3021	interspecies interaction between organisms
FR729_09925	COG0347	Belongs to the P(II) protein family
FR729_09940	COG0825	malonyl-CoA metabolic process
FR729_09945	COG0587	DNA-directed DNA polymerase activity
FR729_09955	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FR729_09960	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FR729_09970	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FR729_09975	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
FR729_09985	COG0750	zinc metalloprotease
FR729_09990	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FR729_09995	COG0575	Belongs to the CDS family
FR729_10000	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FR729_10005	COG0233	cytoplasmic translational termination
FR729_10010	COG0528	UMP kinase activity
FR729_10015	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FR729_10020	COG0052	Belongs to the universal ribosomal protein uS2 family
FR729_10025	COG0024	Methionine aminopeptidase
FR729_10030	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
FR729_10040	COG0564	pseudouridine synthase activity
FR729_10045	COG3098	single-species biofilm formation
FR729_10080	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FR729_10085	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FR729_10110	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
FR729_10120	COG0254	rRNA binding
FR729_10125	COG1720	tRNA m6t6A37 methyltransferase activity
FR729_10130	COG0442	prolyl-tRNA aminoacylation
FR729_10150	COG0733	neurotransmitter:sodium symporter activity
FR729_10170	COG0514	ATP-dependent DNA helicase (RecQ)
FR729_10175	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FR729_10180	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FR729_10210	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FR729_10220	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
FR729_10235	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FR729_10280	COG1477	protein flavinylation
FR729_10285	COG2871	sodium ion transport
FR729_10290	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FR729_10295	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FR729_10300	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FR729_10305	COG1805	sodium ion transport
FR729_10310	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FR729_10315	COG0271	Belongs to the BolA IbaG family
FR729_10320	COG2813	Specifically methylates the guanine in position
FR729_10325	COG3056	Lipoprotein
FR729_10345	COG1595	DNA-templated transcription, initiation
FR729_10365	COG3248	Nucleoside-binding outer membrane protein
FR729_10370	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FR729_10375	COG0693	protein deglycase activity
FR729_10380	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FR729_10385	COG3706	GGDEF domain
FR729_10390	COG2166	iron-sulfur cluster assembly
FR729_10395	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FR729_10400	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
FR729_10415	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
FR729_10415	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FR729_10435	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FR729_10440	COG1074	ATP-dependent DNA helicase activity
FR729_10450	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
FR729_10470	COG3141	response to X-ray
FR729_10485	COG2171	N-acyltransferase activity
FR729_10490	COG0584	glycerophosphoryl diester phosphodiesterase
FR729_10495	COG2271	Major facilitator Superfamily
FR729_10505	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FR729_10510	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FR729_10515	COG1349	DNA-binding transcription factor activity
FR729_10520	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FR729_10525	COG0598	Magnesium transport protein CorA
FR729_10545	COG1609	Transcriptional regulator
FR729_10550	COG0583	DNA-binding transcription factor activity
FR729_10610	COG4964	Belongs to the GSP D family
FR729_10635	COG2169	Transcriptional regulator
FR729_10640	COG1022	Amp-dependent synthetase and ligase
FR729_10650	COG0583	DNA-binding transcription factor activity
FR729_10655	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FR729_10660	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
FR729_10670	COG0560	Phosphoserine phosphatase
FR729_10680	COG0813	purine-nucleoside phosphorylase activity
FR729_10685	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
FR729_10690	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
FR729_10695	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
FR729_10700	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FR729_10705	COG0084	hydrolase, TatD family'
FR729_10735	COG3153	acetyltransferase
FR729_10740	COG3154	lipid carrier protein
FR729_10755	COG0826	peptidase U32
FR729_10760	COG0826	peptidase U32
FR729_10765	COG0534	Mate efflux family protein
FR729_10780	COG1185	polyribonucleotide nucleotidyltransferase activity
FR729_10785	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FR729_10790	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FR729_10795	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FR729_10800	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FR729_10805	COG0195	Participates in both transcription termination and antitermination
FR729_10810	COG0779	Required for maturation of 30S ribosomal subunits
FR729_10825	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FR729_10835	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FR729_10840	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FR729_10845	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FR729_10850	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
FR729_10855	COG1534	Rna-binding protein
FR729_10860	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FR729_10865	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FR729_10870	COG2027	D-alanyl-D-alanine carboxypeptidase
FR729_10880	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FR729_10885	COG0739	heme binding
FR729_10910	COG0628	permease
FR729_10920	COG0784	Response regulator, receiver
FR729_10920	COG2205	protein histidine kinase activity
FR729_10925	COG0747	negative chemotaxis
FR729_10935	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FR729_10940	COG0444	Belongs to the ABC transporter superfamily
FR729_10945	COG4608	Belongs to the ABC transporter superfamily
FR729_10955	COG2971	BadF BadG BcrA BcrD
FR729_10970	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FR729_10975	COG3842	ATPase activity
FR729_10985	COG1840	ABC-type Fe3 transport system, periplasmic component
FR729_10990	COG0004	ammonium transporteR
FR729_11000	COG3112	Uncharacterised protein family (UPF0231)
FR729_11005	COG1049	propionate catabolic process, 2-methylcitrate cycle
FR729_11010	COG1752	Esterase of the alpha-beta hydrolase superfamily
FR729_11015	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FR729_11020	COG1643	Atp-dependent helicase
FR729_11025	COG1489	DNA binding
FR729_11035	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FR729_11045	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FR729_11050	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FR729_11055	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FR729_11060	COG1560	Kdo2-lipid A biosynthetic process
FR729_11070	COG0842	Transport permease protein
FR729_11075	COG1131	(ABC) transporter
FR729_11080	COG0659	secondary active sulfate transmembrane transporter activity
FR729_11085	COG0288	reversible hydration of carbon dioxide
FR729_11100	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FR729_11105	COG0508	dehydrogenase complex catalyzes the overall conversion of
FR729_11110	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
FR729_11115	COG2186	Transcriptional regulator
FR729_11125	COG0157	Belongs to the NadC ModD family
FR729_11135	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FR729_11140	COG1459	type II secretion system
FR729_11150	COG0237	dephospho-CoA kinase activity
FR729_11155	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
FR729_11160	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
FR729_11175	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FR729_11180	COG0228	four-way junction DNA binding
FR729_11185	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FR729_11190	COG4137	Cytochrome C assembly protein
FR729_11195	COG4536	flavin adenine dinucleotide binding
FR729_11200	COG1854	S-ribosylhomocysteine lyase activity
FR729_11215	COG0612	Peptidase, M16
FR729_11220	COG1238	metal cluster binding
FR729_11230	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
FR729_11235	COG0511	ligase activity, forming carbon-carbon bonds
FR729_11235	COG5016	pyruvate
FR729_11240	COG3630	sodium ion export across plasma membrane
FR729_11300	COG0527	aspartate kinase activity
FR729_11305	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FR729_11310	COG2137	regulation of response to DNA damage stimulus
FR729_11320	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FR729_11325	COG1546	Belongs to the CinA family
FR729_11330	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FR729_11335	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FR729_11345	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FR729_11350	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
FR729_11360	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FR729_11365	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FR729_11370	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
FR729_11375	COG0148	phosphopyruvate hydratase activity
FR729_11380	COG0504	CTP synthase activity
FR729_11385	COG3956	TIGRFAM MazG family protein
FR729_11390	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FR729_11400	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FR729_11415	COG0736	holo-[acyl-carrier-protein] synthase activity
FR729_11420	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
FR729_11425	COG1381	Involved in DNA repair and RecF pathway recombination
FR729_11430	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FR729_11440	COG0681	Belongs to the peptidase S26 family
FR729_11445	COG0481	GTPase activity
FR729_11450	COG3086	response to oxidative stress
FR729_11465	COG1595	DNA-templated transcription, initiation
FR729_11475	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FR729_11485	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
FR729_11505	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FR729_11510	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FR729_11515	COG3079	Belongs to the UPF0149 family
FR729_11525	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
FR729_11535	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FR729_11540	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FR729_11545	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FR729_11555	COG0583	DNA-binding transcription factor activity
FR729_11570	COG0668	transmembrane transport
FR729_11575	COG0191	fructose-bisphosphate aldolase activity
FR729_11590	COG4771	TonB-dependent receptor
FR729_11595	COG0583	DNA-binding transcription factor activity
FR729_11600	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FR729_11610	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FR729_11625	COG2356	endonuclease I
FR729_11630	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FR729_11635	COG0189	ligase activity
FR729_11640	COG1678	Uncharacterized ACR, COG1678
FR729_11645	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FR729_11660	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FR729_11665	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FR729_11670	COG0762	integral membrane protein
FR729_11675	COG1872	DUF167
FR729_11685	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FR729_11690	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FR729_11695	COG2066	Belongs to the glutaminase family
FR729_11705	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FR729_11715	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
FR729_11835	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FR729_11845	COG3394	polysaccharide catabolic process
FR729_11850	COG1486	melibiose metabolic process
FR729_11855	COG1447	Phosphotransferase system cellobiose-specific component IIA
FR729_11860	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FR729_11865	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FR729_11870	COG0726	polysaccharide deacetylase
FR729_11970	COG1028	Short-chain dehydrogenase reductase Sdr
FR729_11985	COG0795	lipopolysaccharide-transporting ATPase activity
FR729_11990	COG0795	lipopolysaccharide-transporting ATPase activity
FR729_11995	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FR729_12000	COG2927	DNA polymerase III (CHI subunit)
FR729_12005	COG0525	valine-tRNA ligase activity
FR729_12015	COG0456	acetyltransferase
FR729_12045	COG0540	Belongs to the ATCase OTCase family
FR729_12050	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
FR729_12055	COG0251	oxidation-reduction process
FR729_12060	COG0204	Acyl-transferase
FR729_12065	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FR729_12070	COG5007	Belongs to the BolA IbaG family
FR729_12080	COG2854	intermembrane phospholipid transfer
FR729_12085	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FR729_12090	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FR729_12095	COG1127	ABC transporter
FR729_12105	COG0517	IMP dehydrogenase activity
FR729_12105	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FR729_12115	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
FR729_12120	COG1137	ATPase activity
FR729_12130	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FR729_12135	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FR729_12140	COG1660	Displays ATPase and GTPase activities
FR729_12145	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FR729_12150	COG2239	Acts as a magnesium transporter
FR729_12155	COG0312	modulator of DNA gyrase
FR729_12160	COG3028	Belongs to the UPF0307 family
FR729_12165	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FR729_12170	COG0564	pseudouridine synthase activity
FR729_12180	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FR729_12185	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
FR729_12190	COG0312	modulator of DNA gyrase
FR729_12195	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FR729_12200	COG3164	Protein of unknown function
FR729_12205	COG1530	ribonuclease E activity
FR729_12210	COG0424	maF-like protein
FR729_12215	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
FR729_12220	COG1792	Involved in formation and maintenance of cell shape
FR729_12225	COG1077	Cell shape determining protein MreB Mrl
FR729_12270	COG1459	type II secretion system
FR729_12275	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FR729_12285	COG3409	Peptidoglycan-binding domain 1 protein
FR729_12285	COG3267	Type II secretory pathway component ExeA
FR729_12290	COG1450	Type ii and iii secretion system protein
FR729_12310	COG2199	diguanylate cyclase activity
FR729_12310	COG2200	EAL domain
FR729_12315	COG0629	single-stranded DNA binding
FR729_12330	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FR729_12340	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FR729_12350	COG0527	aspartate kinase activity
FR729_12355	COG0646	methionine synthase
FR729_12355	COG1410	methionine synthase
FR729_12420	COG0175	sulfate reduction
FR729_12425	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FR729_12430	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FR729_12450	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FR729_12455	COG0735	belongs to the Fur family
FR729_12465	COG0166	Belongs to the GPI family
FR729_12470	COG0432	Pfam Uncharacterised protein family UPF0047
FR729_12475	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FR729_12500	COG2965	DNA replication, synthesis of RNA primer
FR729_12505	COG0360	Binds together with S18 to 16S ribosomal RNA
FR729_12510	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FR729_12515	COG0338	D12 class N6 adenine-specific DNA methyltransferase
FR729_12525	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FR729_12530	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FR729_12560	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FR729_12570	COG0678	peroxiredoxin activity
FR729_12570	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FR729_12575	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FR729_12585	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
FR729_12585	COG0165	Argininosuccinate lyase
FR729_12590	COG0137	argininosuccinate synthase activity
FR729_12600	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FR729_12610	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
FR729_12620	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FR729_12625	COG0460	homoserine dehydrogenase
FR729_12625	COG0527	aspartate kinase activity
FR729_12630	COG0626	cystathionine gamma-synthase activity
FR729_12640	COG0281	malic enzyme
FR729_12655	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FR729_12660	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FR729_12680	COG2923	Belongs to the DsrF TusC family
FR729_12685	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
FR729_12690	COG2964	Protein conserved in bacteria
FR729_12695	COG0545	Peptidyl-prolyl cis-trans isomerase
FR729_12710	COG1446	asparaginase
FR729_12720	COG1047	Peptidyl-prolyl cis-trans
FR729_12735	COG2249	NAD(P)H dehydrogenase (quinone) activity
FR729_12740	COG0488	(ABC) transporter
FR729_12750	COG0429	hydrolase of the alpha beta-hydrolase fold
FR729_12760	COG3954	Phosphoribulokinase
FR729_12765	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FR729_12785	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FR729_12790	COG0512	Glutamine amidotransferase of anthranilate synthase
FR729_12805	COG0180	Tryptophanyl-tRNA synthetase
FR729_12810	COG0546	phosphoglycolate phosphatase activity
FR729_12815	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FR729_12820	COG0557	exoribonuclease II activity
FR729_12825	COG1959	2 iron, 2 sulfur cluster binding
FR729_12830	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FR729_12830	COG1017	nitric oxide dioxygenase activity
FR729_12835	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
FR729_12845	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FR729_12850	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
FR729_12855	COG0330	HflC and HflK could
FR729_12860	COG0330	HflC and HflK could
FR729_12865	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FR729_12875	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FR729_12880	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FR729_12890	COG0802	atpase or kinase
FR729_12900	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FR729_12965	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
FR729_12970	COG1162	GTPase activity
FR729_12975	COG0688	phosphatidylethanolamine metabolic process
FR729_12980	COG3273	potassium ion transport
FR729_12980	COG0471	metal ion transport
FR729_12990	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FR729_12995	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FR729_13000	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
FR729_13005	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FR729_13010	COG1045	serine acetyltransferase
FR729_13015	COG4942	peptidase
FR729_13035	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
FR729_13040	COG1053	succinate dehydrogenase
FR729_13045	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FR729_13050	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
FR729_13055	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
FR729_13070	COG1509	lysine 2,3-aminomutase activity
FR729_13075	COG1285	pathogenesis
FR729_13085	COG0459	protein refolding
FR729_13095	COG0534	Mate efflux family protein
FR729_13100	COG0205	6-phosphofructokinase activity
FR729_13110	COG3678	ATP-independent chaperone mediated protein folding
FR729_13115	COG0745	RESPONSE REGULATOR receiver
FR729_13120	COG2205	protein histidine kinase activity
FR729_13130	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FR729_13135	COG3030	protein affecting phage T7 exclusion by the F plasmid
FR729_13140	COG1027	Aspartate ammonia-lyase
FR729_13145	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
FR729_13150	COG4232	protein-disulfide reductase activity
FR729_13160	COG3263	regulation of cellular component size
FR729_13170	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FR729_13195	COG2814	Major facilitator Superfamily
FR729_13210	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FR729_13215	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FR729_13220	COG0511	ligase activity, forming carbon-carbon bonds
FR729_13225	COG0439	Biotin carboxylase
FR729_13230	COG2264	protein methyltransferase activity
FR729_13235	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FR729_13240	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
FR729_13250	COG0488	(ABC) transporter
FR729_13310	COG1982	Orn Lys Arg decarboxylase major
FR729_13315	COG0531	amino acid
FR729_13325	COG3710	Transcriptional regulator
FR729_13330	COG0789	Transcriptional regulator
FR729_13345	COG0151	Belongs to the GarS family
FR729_13360	COG1253	flavin adenine dinucleotide binding
FR729_13365	COG3068	Protein conserved in bacteria
FR729_13375	COG1573	uracil-dna glycosylase
FR729_13380	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FR729_13385	COG2816	NAD+ diphosphatase activity
FR729_13390	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
FR729_13395	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FR729_13400	COG0085	RNA polymerase activity
FR729_13405	COG0222	ribosome binding
FR729_13410	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FR729_13425	COG0250	Participates in transcription elongation, termination and antitermination
FR729_13430	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FR729_13440	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FR729_13475	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
FR729_13475	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
FR729_13480	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FR729_13490	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FR729_13530	COG4206	TonB-dependent receptor
FR729_13560	COG0739	heme binding
FR729_13575	COG3547	Transposase (IS116 IS110 IS902 family)
FR729_13710	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FR729_13715	COG0534	Mate efflux family protein
FR729_13720	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
FR729_13730	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FR729_13740	COG2937	Belongs to the GPAT DAPAT family
FR729_13745	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
FR729_13750	COG3161	chorismate lyase activity
FR729_13755	COG1580	Controls the rotational direction of flagella during chemotaxis
FR729_13760	COG0705	Rhomboid family
FR729_13765	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FR729_13780	COG2177	Part of the ABC transporter FtsEX involved in
FR729_13785	COG2884	Cell division ATP-binding protein ftsE
FR729_13790	COG0552	protein localization to endoplasmic reticulum
FR729_13795	COG0742	ribosomal rna small subunit methyltransferase
FR729_13805	COG2095	MarC family integral membrane protein
FR729_13850	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FR729_13855	COG0640	Transcriptional regulator
FR729_13860	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
FR729_13865	COG1280	lysine exporter protein (LysE YggA)
FR729_13870	COG2267	carboxylic ester hydrolase activity
FR729_13875	COG0561	phosphatase activity
FR729_13895	COG2199	diguanylate cyclase activity
FR729_13895	COG2200	EAL domain
FR729_13895	COG3287	FIST C domain
FR729_13900	COG1011	Hydrolase
FR729_13905	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
FR729_13920	COG0019	diaminopimelate decarboxylase activity
FR729_13930	COG1965	Belongs to the frataxin family
FR729_13935	COG3072	Adenylate cyclase
FR729_13940	COG0181	hydroxymethylbilane synthase activity
FR729_13945	COG1587	Uroporphyrinogen-III synthase
FR729_13950	COG2959	enzyme of heme biosynthesis
FR729_13955	COG3071	HemY protein
FR729_14000	COG0633	Ferredoxin
FR729_14005	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
FR729_14020	COG3118	belongs to the thioredoxin family
FR729_14025	COG0513	Belongs to the DEAD box helicase family
FR729_14040	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
FR729_14055	COG0514	ATP-dependent DNA helicase (RecQ)
FR729_14060	COG2962	Rard protein
FR729_14070	COG1280	lysine exporter protein (LysE YggA)
FR729_14075	COG0405	Gamma-glutamyltransferase
FR729_14085	COG0210	DNA helicase
FR729_14095	COG3220	belongs to the UPF0276 family
FR729_14125	COG0006	proline dipeptidase activity
FR729_14125	COG0006	proline dipeptidase activity
FR729_14140	COG2104	thiamine diphosphate biosynthetic process
FR729_14145	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FR729_14165	COG2132	Multicopper oxidase
FR729_14215	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FR729_14220	COG1739	Uncharacterized protein family UPF0029
FR729_14230	COG0183	Belongs to the thiolase family
FR729_14235	COG0604	alcohol dehydrogenase
FR729_14250	COG0425	Belongs to the sulfur carrier protein TusA family
FR729_14260	COG2119	membrane
FR729_14275	COG0366	Alpha amylase catalytic
FR729_14280	COG3977	Valine--pyruvate aminotransferase
FR729_14285	COG0071	Belongs to the small heat shock protein (HSP20) family
FR729_14300	COG0187	DNA topoisomerase II activity
FR729_14310	COG0592	DNA-directed DNA polymerase activity
FR729_14315	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FR729_14335	COG1126	abc transporter atp-binding protein
FR729_14345	COG0594	ribonuclease P activity
FR729_14355	COG0706	membrane insertase activity
FR729_14365	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FR729_14370	COG0445	tRNA wobble uridine modification
FR729_14375	COG0357	Ribosomal RNA small subunit methyltransferase G
FR729_14380	COG1192	Involved in chromosome partitioning
FR729_14385	COG1475	DNA binding
FR729_14390	COG3312	ion transport
FR729_14395	COG0356	it plays a direct role in the translocation of protons across the membrane
FR729_14405	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FR729_14410	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FR729_14415	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FR729_14420	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FR729_14425	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FR729_14430	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FR729_14440	COG0765	amino acid transport
FR729_14450	COG2814	Major facilitator Superfamily
FR729_14455	COG0583	DNA-binding transcription factor activity
FR729_14465	COG0129	dihydroxy-acid dehydratase activity
FR729_14470	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FR729_14475	COG3978	acetolactate synthase activity
FR729_14485	COG0606	chelatase, subunit chli
FR729_14495	COG0204	Acyl-transferase
FR729_14500	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FR729_14505	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FR729_14515	COG3084	Protein conserved in bacteria
FR729_14525	COG4326	sporulation control protein
FR729_14530	COG1272	protein, Hemolysin III
FR729_14540	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FR729_14545	COG0569	domain protein
FR729_14550	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FR729_14550	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FR729_14555	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FR729_14560	COG0242	peptide deformylase activity
FR729_14570	COG0758	DNA mediated transformation
FR729_14575	COG2922	Belongs to the Smg family
FR729_14585	COG0551	DNA topoisomerase type I activity
FR729_14590	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FR729_14595	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FR729_14600	COG0009	L-threonylcarbamoyladenylate synthase
FR729_14620	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FR729_14655	COG0583	DNA-binding transcription factor activity
FR729_14660	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FR729_14665	COG2960	long-chain fatty acid transporting porin activity
FR729_14670	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FR729_14675	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FR729_14735	COG4166	transmembrane transport
FR729_14745	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FR729_14785	COG1609	Transcriptional regulator
FR729_14790	COG0583	DNA-binding transcription factor activity
FR729_14805	COG0129	dihydroxy-acid dehydratase activity
FR729_14810	COG3265	gluconokinase activity
FR729_14815	COG2610	gluconate transmembrane transporter activity
FR729_14820	COG0800	Aldolase
FR729_14825	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
FR729_14830	COG0583	DNA-binding transcription factor activity
FR729_14835	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FR729_14840	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
FR729_14850	COG1522	sequence-specific DNA binding
FR729_14855	COG5001	Diguanylate cyclase
FR729_14855	COG5002	protein histidine kinase activity
FR729_14860	COG0742	ribosomal rna small subunit methyltransferase
FR729_14875	COG0589	response to stress
FR729_14880	COG1528	Iron-storage protein
FR729_14920	COG2081	HI0933 family
FR729_14970	COG0210	DNA helicase
FR729_15025	COG1597	lipid kinase activity
FR729_15055	COG0628	permease
FR729_15070	COG1322	Protein conserved in bacteria
FR729_15075	COG2226	methyltransferase
FR729_15080	COG3165	ubiquinone biosynthetic process from chorismate
FR729_15085	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FR729_15095	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FR729_15100	COG0805	protein transport
FR729_15110	COG0084	hydrolase, TatD family'
FR729_15125	COG0456	acetyltransferase
FR729_15135	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FR729_15135	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FR729_15140	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FR729_15175	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FR729_15185	COG2204	response regulator
FR729_15190	COG3852	Histidine kinase
FR729_15200	COG0174	glutamine synthetase
FR729_15210	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FR729_15220	COG1295	ribonuclease BN
FR729_15225	COG1490	D-aminoacyl-tRNA deacylase activity
FR729_15230	COG0456	acetyltransferase
FR729_15240	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
FR729_15245	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
FR729_15250	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FR729_15255	COG3031	protein transport across the cell outer membrane
FR729_15265	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FR729_15270	COG1459	type II secretion system
FR729_15275	COG2165	general secretion pathway protein
FR729_15280	COG2165	general secretion pathway protein
FR729_15285	COG2165	general secretion pathway protein
FR729_15290	COG4795	General secretion pathway protein
FR729_15295	COG3156	type II secretion system protein K
FR729_15300	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
FR729_15305	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
FR729_15315	COG1218	3'(2'),5'-bisphosphate nucleotidase
FR729_15320	COG0494	nUDIX hydrolase
FR729_15330	COG1040	competence protein
FR729_15345	COG2183	response to ionizing radiation
FR729_15355	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FR729_15365	COG0745	RESPONSE REGULATOR receiver
FR729_15375	COG2233	PERMEase
FR729_15380	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FR729_15385	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FR729_15390	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FR729_15395	COG1758	RNA polymerase activity
FR729_15400	COG0194	GDP metabolic process
FR729_15420	COG0848	biopolymer transport protein
FR729_15425	COG0811	peptide transport
FR729_15450	COG4174	ABC transporter (Permease)
FR729_15455	COG4239	(ABC) transporter, permease
FR729_15460	COG0747	negative chemotaxis
FR729_15465	COG0444	Belongs to the ABC transporter superfamily
FR729_15470	COG4608	Belongs to the ABC transporter superfamily
FR729_15510	COG2003	Belongs to the UPF0758 family
FR729_15515	COG0328	RNA-DNA hybrid ribonuclease activity
FR729_15525	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
FR729_15555	COG1561	YicC-like family, N-terminal region
FR729_15565	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
FR729_15575	COG1560	Kdo2-lipid A biosynthetic process
FR729_15580	COG1309	transcriptional regulator
FR729_15585	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FR729_15595	COG0840	transmembrane signaling receptor activity
FR729_15600	COG2003	Belongs to the UPF0758 family
FR729_15625	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FR729_15640	COG0463	Glycosyl transferase, family 2
FR729_15645	COG0859	PFAM glycosyl transferase family 9
FR729_15650	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FR729_15655	COG3642	lipopolysaccharide core region biosynthetic process
FR729_15665	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FR729_15705	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FR729_15710	COG1519	Transferase
FR729_15715	COG0859	PFAM glycosyl transferase family 9
FR729_15725	COG1560	Kdo2-lipid A biosynthetic process
FR729_15735	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FR729_15800	COG1215	transferase activity, transferring glycosyl groups
FR729_15805	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FR729_15810	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
FR729_15815	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FR729_15835	COG0438	transferase activity, transferring glycosyl groups
FR729_15875	COG0149	triose-phosphate isomerase activity
FR729_15905	COG1494	fructose-1,6-bisphosphatase
FR729_15915	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FR729_15920	COG1575	Belongs to the MenA family. Type 1 subfamily
FR729_15925	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
FR729_15930	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
FR729_15940	COG1609	Transcriptional regulator
FR729_15945	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FR729_15955	COG0254	rRNA binding
FR729_15965	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FR729_15970	COG0088	Forms part of the polypeptide exit tunnel
FR729_15980	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FR729_15985	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FR729_15990	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FR729_15995	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FR729_16005	COG0255	Belongs to the universal ribosomal protein uL29 family
FR729_16010	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FR729_16020	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FR729_16025	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FR729_16035	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FR729_16040	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FR729_16055	COG1841	ribosomal large subunit assembly
FR729_16065	COG0201	protein transport
FR729_16070	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FR729_16075	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FR729_16080	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FR729_16090	COG0202	RNA polymerase activity
FR729_16095	COG0203	ribosomal protein L17
FR729_16105	COG0545	Peptidyl-prolyl cis-trans isomerase
FR729_16115	COG2153	protein acetylation
FR729_16120	COG0513	Belongs to the DEAD box helicase family
FR729_16135	COG1648	precorrin-2 dehydrogenase activity
FR729_16135	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FR729_16140	COG0175	sulfate reduction
FR729_16145	COG2895	sulfate adenylyltransferase (ATP) activity
FR729_16150	COG3273	potassium ion transport
FR729_16150	COG0471	metal ion transport
FR729_16155	COG0529	Catalyzes the synthesis of activated sulfate
FR729_16175	COG4181	ATPase activity
FR729_16190	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
FR729_16200	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FR729_16205	COG0729	surface antigen
FR729_16210	COG2911	Protein conserved in bacteria
FR729_16215	COG2105	PFAM AIG2 family protein
FR729_16225	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FR729_16230	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
FR729_16240	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FR729_16245	COG0163	prenyltransferase activity
FR729_16255	COG1178	ABC-type Fe3 transport system permease component
FR729_16260	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
FR729_16265	COG0583	DNA-binding transcription factor activity
FR729_16270	COG1902	pentaerythritol trinitrate reductase activity
FR729_16290	COG2358	TRAP transporter, solute receptor (TAXI family
FR729_16315	COG0142	geranyltranstransferase activity
FR729_16320	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FR729_16330	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FR729_16335	COG2966	Psort location CytoplasmicMembrane, score
FR729_16350	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FR729_16355	COG2967	ApaG domain
FR729_16360	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FR729_16365	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FR729_16370	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FR729_16375	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
FR729_16380	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
FR729_16400	COG0473	3-isopropylmalate dehydrogenase activity
FR729_16405	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FR729_16430	COG0583	DNA-binding transcription factor activity
FR729_16435	COG1022	Amp-dependent synthetase and ligase
FR729_16440	COG0028	Belongs to the TPP enzyme family
FR729_16445	COG0440	acetolactate synthase activity
FR729_16450	COG3706	GGDEF domain
FR729_16460	COG0469	pyruvate kinase activity
FR729_16465	COG1349	DNA-binding transcription factor activity
FR729_16470	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FR729_16480	COG2376	Dihydroxyacetone kinase
FR729_16485	COG1461	Dihydroxyacetone kinase
FR729_16500	COG3722	fumarate hydratase activity
FR729_16510	COG2213	PTS system mannitol-specific
FR729_16510	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
FR729_16565	COG1902	pentaerythritol trinitrate reductase activity
FR729_16570	COG1063	alcohol dehydrogenase
FR729_16580	COG1028	Short-chain dehydrogenase reductase Sdr
FR729_16590	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FR729_16595	COG0006	proline dipeptidase activity
FR729_16600	COG3608	succinylglutamate desuccinylase aspartoacylase
FR729_16605	COG1522	sequence-specific DNA binding
FR729_16610	COG1012	belongs to the aldehyde dehydrogenase family
FR729_16615	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FR729_16620	COG3122	Protein conserved in bacteria
FR729_16635	COG0583	DNA-binding transcription factor activity
FR729_16645	COG0252	asparaginase activity
FR729_16650	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
FR729_16665	COG2197	response regulator
FR729_16670	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FR729_16695	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FR729_16725	COG3842	ATPase activity
FR729_16770	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FR729_16775	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FR729_16810	COG0583	DNA-binding transcription factor activity
FR729_16820	COG4948	Mandelate Racemase Muconate Lactonizing
FR729_16855	COG1342	Belongs to the UPF0251 family
FR729_16865	COG4176	ABC-type proline glycine betaine transport system permease component
FR729_16870	COG4175	Glycine betaine
FR729_16870	COG3448	diguanylate cyclase activity
FR729_16875	COG3015	lipoprotein NlpE involved in copper resistance
FR729_16880	COG3713	MltA-interacting MipA family protein
FR729_16895	COG0583	DNA-binding transcription factor activity
FR729_16920	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FR729_16930	COG1335	isochorismatase
FR729_16945	COG1349	DNA-binding transcription factor activity
FR729_16950	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FR729_16950	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FR729_16955	COG2070	2-Nitropropane dioxygenase
FR729_16960	COG0531	amino acid
FR729_16965	COG4302	ethanolamine ammonia-lyase activity
FR729_16970	COG4303	Ethanolamine ammonia lyase large subunit
FR729_16980	COG1309	transcriptional regulator
FR729_17000	COG1280	lysine exporter protein (LysE YggA)
FR729_17010	COG0459	protein refolding
FR729_17015	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FR729_17025	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FR729_17040	COG1304	FMN binding
FR729_17065	COG1256	bacterial-type flagellum assembly
FR729_17065	COG4786	Flagellar basal body rod
FR729_17075	COG1706	bacterial-type flagellum-dependent cell motility
FR729_17080	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
FR729_17085	COG4786	Flagellar basal body rod
FR729_17090	COG4787	bacterial-type flagellum-dependent cell motility
FR729_17105	COG1558	bacterial-type flagellum-dependent cell motility
FR729_17110	COG1815	bacterial-type flagellum-dependent cell motility
FR729_17130	COG0741	lytic transglycosylase activity
FR729_17135	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FR729_17155	COG1760	l-serine dehydratase
FR729_17170	COG0583	DNA-binding transcription factor activity
FR729_17180	COG2866	Carboxypeptidase
FR729_17185	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FR729_17195	COG2990	Protein conserved in bacteria
FR729_17220	COG3842	ATPase activity
FR729_17225	COG1840	ABC-type Fe3 transport system, periplasmic component
FR729_17245	COG1609	Transcriptional regulator
FR729_17275	COG3240	lipase activity
FR729_17280	COG1309	transcriptional regulator
FR729_17295	COG1136	(ABC) transporter
FR729_17295	COG0577	efflux transmembrane transporter activity
FR729_17300	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FR729_17305	COG2067	long-chain fatty acid transport protein
FR729_17315	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
FR729_17330	COG1011	Hydrolase
FR729_17370	COG0110	maltose O-acetyltransferase activity
FR729_17375	COG1765	OsmC-like protein
FR729_17380	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FR729_17380	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FR729_17395	COG3046	protein related to deoxyribodipyrimidine photolyase
FR729_17400	COG0415	Belongs to the DNA photolyase family
FR729_17405	COG3706	GGDEF domain
FR729_17420	COG3706	GGDEF domain
FR729_17435	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FR729_17455	COG3033	Beta-eliminating lyase
FR729_17465	COG1271	oxidase subunit
FR729_17470	COG1294	oxidase, subunit
FR729_17485	COG0579	oxidoreductase
FR729_17510	COG3706	GGDEF domain
FR729_17520	COG4191	Histidine kinase
FR729_17545	COG0583	DNA-binding transcription factor activity
FR729_17570	COG0189	ligase activity
FR729_17575	COG4067	protein conserved in archaea
FR729_17575	COG0189	ligase activity
FR729_17585	COG1166	arginine decarboxylase activity
FR729_17590	COG0010	Belongs to the arginase family
FR729_17595	COG2814	Major facilitator Superfamily
FR729_17600	COG1770	oligopeptidase
FR729_17615	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FR729_17620	COG1121	(ABC) transporter
FR729_17625	COG0803	Belongs to the bacterial solute-binding protein 9 family
FR729_17665	COG0848	biopolymer transport protein
FR729_17670	COG0811	peptide transport
FR729_17675	COG0811	peptide transport
FR729_17695	COG0745	RESPONSE REGULATOR receiver
FR729_17700	COG0584	glycerophosphoryl diester phosphodiesterase
FR729_17770	COG1901	pseudouridine methyltransferase
FR729_17775	COG0312	modulator of DNA gyrase
FR729_17785	COG0351	phosphomethylpyrimidine kinase
FR729_17790	COG1116	anion transmembrane transporter activity
FR729_17795	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FR729_17800	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FR729_17805	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FR729_17825	COG0243	molybdopterin cofactor binding
FR729_17830	COG3005	denitrification pathway
FR729_17835	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FR729_17840	COG1028	Short-chain dehydrogenase reductase Sdr
FR729_17855	COG0456	acetyltransferase
FR729_17875	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FR729_17880	COG1929	Belongs to the glycerate kinase type-1 family
FR729_17885	COG2610	gluconate transmembrane transporter activity
FR729_17890	COG3835	regulator
FR729_17950	COG3047	cAMP biosynthetic process
FR729_17955	COG1357	PFAM Pentapeptide repeats (8 copies)
FR729_17985	COG2375	cellular response to nickel ion
FR729_17990	COG0583	DNA-binding transcription factor activity
FR729_17995	COG2162	N-hydroxyarylamine O-acetyltransferase activity
FR729_18000	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
FR729_18015	COG2199	diguanylate cyclase activity
FR729_18025	COG0561	phosphatase activity
FR729_18030	COG0583	DNA-binding transcription factor activity
FR729_18045	COG0564	pseudouridine synthase activity
FR729_18050	COG0534	Mate efflux family protein
FR729_18065	COG3123	guanosine phosphorylase activity
FR729_18080	COG0596	Alpha beta hydrolase
FR729_18105	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FR729_18115	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FR729_18120	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FR729_18120	COG2169	Transcriptional regulator
FR729_18130	COG2259	Doxx family
FR729_18135	COG1741	Belongs to the pirin family
FR729_18155	COG0363	glucosamine-6-phosphate deaminase activity
FR729_18165	COG0786	glutamate:sodium symporter activity
FR729_18170	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FR729_18175	COG1131	(ABC) transporter
FR729_18185	COG0786	glutamate:sodium symporter activity
FR729_18210	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FR729_18220	COG3279	Response regulator of the LytR AlgR family
FR729_18225	COG3275	phosphorelay sensor kinase activity
FR729_18245	COG1136	(ABC) transporter
FR729_18255	COG0772	Belongs to the SEDS family
FR729_18280	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FR729_18280	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
FR729_18290	COG0444	Belongs to the ABC transporter superfamily
FR729_18295	COG4608	Belongs to the ABC transporter superfamily
FR729_18320	COG1444	tRNA N-acetyltransferase activity
FR729_18340	COG3340	Belongs to the peptidase S51 family
FR729_18345	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FR729_18350	COG1263	PTS System
FR729_18350	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FR729_18355	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
FR729_18375	COG4166	transmembrane transport
FR729_18430	COG0259	pyridoxamine-phosphate oxidase activity
FR729_18455	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FR729_18495	COG1132	(ABC) transporter
FR729_18505	COG0513	Belongs to the DEAD box helicase family
FR729_18510	COG2258	MOSC domain
FR729_18565	COG3634	alkyl hydroperoxide reductase activity
FR729_18575	COG1846	Transcriptional regulator
FR729_18580	COG1764	response to oxidative stress
FR729_18620	COG1136	(ABC) transporter
FR729_18640	COG0463	Glycosyl transferase, family 2
FR729_18680	COG0745	RESPONSE REGULATOR receiver
FR729_18690	COG1653	transport
FR729_18695	COG0019	diaminopimelate decarboxylase activity
FR729_18700	COG4264	IucA IucC family
FR729_18725	COG4772	TonB-dependent receptor
FR729_18730	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
FR729_18735	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FR729_18740	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FR729_18745	COG1120	ATPase activity
FR729_18750	COG0840	transmembrane signaling receptor activity
FR729_18755	COG0612	Peptidase, M16
FR729_18765	COG0739	heme binding
FR729_18780	COG2814	Major facilitator Superfamily
FR729_18790	COG1609	Transcriptional regulator
FR729_18795	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FR729_18820	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FR729_18825	COG1609	Transcriptional regulator
FR729_18835	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FR729_18875	COG1760	l-serine dehydratase
FR729_18885	COG4580	involved in the transport of maltose and maltodextrins
FR729_18905	COG2356	endonuclease I
FR729_18925	COG1982	Orn Lys Arg decarboxylase major
FR729_18930	COG0531	amino acid
FR729_18940	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
FR729_18945	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
FR729_18950	COG1162	GTPase activity
FR729_18955	COG1263	PTS System
FR729_18955	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FR729_18960	COG1999	signal sequence binding
FR729_18975	COG2909	trisaccharide binding
FR729_18980	COG0058	SHG alpha-glucan phosphorylase activity
FR729_18985	COG1640	4-alpha-glucanotransferase
FR729_18990	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FR729_18995	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FR729_19000	COG0366	Alpha amylase catalytic
FR729_19015	COG3366	ferrous iron transmembrane transporter activity
FR729_19020	COG0700	Nucleoside recognition
FR729_19025	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FR729_19030	COG3339	Conserved Protein
FR729_19045	COG1301	dicarboxylic acid transport
FR729_19055	COG0583	DNA-binding transcription factor activity
FR729_19075	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FR729_19080	COG1596	polysaccharide export
FR729_19095	COG2095	MarC family integral membrane protein
FR729_19100	COG4667	esterase of the alpha-beta hydrolase superfamily
FR729_19105	COG3397	chitin binding
FR729_19110	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
FR729_19115	COG0415	Belongs to the DNA photolyase family
FR729_19135	COG1686	Belongs to the peptidase S11 family
FR729_19160	COG0583	DNA-binding transcription factor activity
FR729_19165	COG4628	conserved protein (DUF2132)
FR729_19185	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
FR729_19190	COG0628	permease
FR729_19235	COG2814	Major facilitator Superfamily
FR729_19245	COG0454	-acetyltransferase
FR729_19255	COG0745	RESPONSE REGULATOR receiver
FR729_19260	COG2205	protein histidine kinase activity
FR729_19275	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FR729_19280	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FR729_19285	COG1882	Formate acetyltransferase
FR729_19320	COG1360	Flagellar Motor Protein
FR729_19325	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FR729_19330	COG1191	sigma factor activity
FR729_19335	COG1580	Controls the rotational direction of flagella during chemotaxis
FR729_19350	COG1516	flagellar protein fliS
FR729_19355	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
FR729_19365	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FR729_19380	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FR729_19390	COG1987	bacterial-type flagellum assembly
FR729_19430	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FR729_19490	COG0346	lactoylglutathione lyase activity
FR729_19515	COG0745	RESPONSE REGULATOR receiver
FR729_19540	COG3300	MHYT domain
FR729_19540	COG5001	Diguanylate cyclase
FR729_19545	COG0156	8-amino-7-oxononanoate synthase activity
FR729_19550	COG1063	alcohol dehydrogenase
FR729_19585	COG0668	transmembrane transport
FR729_19595	COG1304	FMN binding
FR729_19600	COG1620	l-lactate permease
FR729_19605	COG0583	DNA-binding transcription factor activity
FR729_19610	COG1505	serine-type exopeptidase activity
FR729_19615	COG4172	Belongs to the ABC transporter superfamily
FR729_19625	COG1067	ATP-dependent peptidase activity
FR729_19635	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FR729_19655	COG1247	-acetyltransferase
FR729_19660	COG0437	4 iron, 4 sulfur cluster binding
FR729_19665	COG0348	domain, Protein
FR729_19685	COG1122	ATPase activity
FR729_19690	COG4720	Psort location CytoplasmicMembrane, score
FR729_19695	COG1566	PFAM secretion protein HlyD family protein
FR729_19705	COG3706	GGDEF domain
FR729_19720	COG0813	purine-nucleoside phosphorylase activity
FR729_19725	COG3272	Protein of unknown function (DUF1722)
FR729_19730	COG0789	Transcriptional regulator
FR729_19735	COG0415	Belongs to the DNA photolyase family
FR729_19740	COG1376	ErfK ybiS ycfS ynhG family protein
FR729_19740	COG1388	LysM domain
FR729_19750	COG0513	Belongs to the DEAD box helicase family
FR729_19755	COG1770	oligopeptidase
FR729_19760	COG4771	TonB-dependent receptor
FR729_19790	COG0573	inorganic phosphate transmembrane transporter activity
FR729_19795	COG0581	inorganic phosphate transmembrane transporter activity
FR729_19800	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FR729_19815	COG2304	oxidoreductase activity
FR729_19835	COG0714	Associated with various cellular activities
FR729_19850	COG2197	response regulator
FR729_19885	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
FR729_19890	COG1120	ATPase activity
FR729_19895	COG4774	siderophore transport
FR729_19900	COG1132	(ABC) transporter
FR729_19905	COG2205	protein histidine kinase activity
FR729_19915	COG0569	domain protein
FR729_19920	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FR729_19925	COG0583	DNA-binding transcription factor activity
FR729_19945	COG1012	belongs to the aldehyde dehydrogenase family
FR729_19950	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FR729_19955	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FR729_19965	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
FR729_19970	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FR729_20000	COG2084	Dehydrogenase
FR729_20005	COG0753	catalase activity
FR729_20015	COG2130	NADP-dependent
FR729_20020	COG1309	transcriptional regulator
FR729_20065	COG0489	protein tyrosine kinase activity
FR729_20065	COG3206	protein involved in exopolysaccharide biosynthesis
FR729_20080	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FR729_20085	COG3842	ATPase activity
FR729_20095	COG1175	transmembrane transport
FR729_20100	COG3833	ABC-type maltose transport systems, permease component
FR729_20130	COG2354	Protein conserved in bacteria
FR729_20135	COG0418	dihydroorotase activity
FR729_20145	COG0401	homolog of Blt101
FR729_20150	COG0633	Ferredoxin
FR729_20150	COG3217	Mosc domain protein beta barrel domain protein
FR729_20150	COG0633	Ferredoxin
FR729_20150	COG3217	Mosc domain protein beta barrel domain protein
FR729_20160	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FR729_20200	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
FR729_20205	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FR729_20215	COG0848	biopolymer transport protein
FR729_20220	COG0811	peptide transport
FR729_20225	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
FR729_20235	COG3721	Heme iron utilization protein
FR729_20240	COG0748	coenzyme F420 binding
FR729_20255	COG0784	Response regulator, receiver
FR729_20255	COG0835	chemotaxis
FR729_20260	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FR729_20265	COG0534	Mate efflux family protein
FR729_20270	COG0444	Belongs to the ABC transporter superfamily
FR729_20275	COG4608	Belongs to the ABC transporter superfamily
FR729_20280	COG0747	negative chemotaxis
FR729_20290	COG1349	DNA-binding transcription factor activity
FR729_20295	COG2084	Dehydrogenase
FR729_20300	COG3395	kinase activity
FR729_20305	COG0235	Class ii aldolase
FR729_20310	COG3622	Belongs to the hyi family
FR729_20315	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FR729_20320	COG2610	gluconate transmembrane transporter activity
FR729_20345	COG0583	DNA-binding transcription factor activity
FR729_20350	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FR729_20360	COG4934	collagen metabolic process
FR729_20370	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FR729_20375	COG0789	Transcriptional regulator
FR729_20380	COG0366	Alpha amylase catalytic
FR729_20400	COG2249	NAD(P)H dehydrogenase (quinone) activity
FR729_20405	COG0589	response to stress
FR729_20410	COG0488	(ABC) transporter
FR729_20415	COG1505	serine-type exopeptidase activity
FR729_20425	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FR729_20435	COG2067	long-chain fatty acid transport protein
FR729_20445	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FR729_20470	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FR729_20490	COG3383	formate dehydrogenase (NAD+) activity
FR729_20500	COG0842	Transport permease protein
FR729_20505	COG1131	(ABC) transporter
FR729_20520	COG1881	PFAM PEBP family protein
FR729_20530	COG0798	PFAM Bile acid sodium symporter
FR729_20545	COG1733	regulation of RNA biosynthetic process
FR729_20570	COG4989	oxidoreductase activity
FR729_20595	COG0814	amino acid
FR729_20635	COG0739	heme binding
FR729_20640	COG5001	Diguanylate cyclase
FR729_20645	COG0583	DNA-binding transcription factor activity
FR729_20650	COG2814	Major facilitator Superfamily
FR729_20670	COG0697	spore germination
FR729_20685	COG0179	Fumarylacetoacetate (FAA) hydrolase
FR729_20705	COG1280	lysine exporter protein (LysE YggA)
FR729_20720	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FR729_20725	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FR729_20730	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
FR729_20735	COG1845	cytochrome c oxidase, subunit III
FR729_20755	COG1612	heme a metabolic process
FR729_20760	COG0109	protoheme IX farnesyltransferase activity
FR729_20765	COG0545	Peptidyl-prolyl cis-trans isomerase
FR729_20795	COG1278	Cold shock
FR729_20800	COG3036	rescue of stalled ribosome
FR729_20805	COG2199	diguanylate cyclase activity
FR729_20820	COG1132	(ABC) transporter
FR729_20830	COG1538	Outer membrane efflux protein
FR729_20835	COG2205	protein histidine kinase activity
FR729_20835	COG0784	Response regulator, receiver
FR729_20860	COG0840	transmembrane signaling receptor activity
FR729_20865	COG0783	Belongs to the Dps family
FR729_20875	COG2133	pyrroloquinoline quinone binding
FR729_20880	COG1454	alcohol dehydrogenase
FR729_20885	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
FR729_20905	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FR729_20910	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FR729_20915	COG3186	Phenylalanine-4-hydroxylase
FR729_20940	COG3530	Putative quorum-sensing-regulated virulence factor
FR729_20955	COG2186	Transcriptional regulator
FR729_20970	COG1279	arginine transmembrane transporter activity
FR729_20985	COG0730	response to heat
FR729_20995	COG0513	Belongs to the DEAD box helicase family
FR729_21000	COG4628	conserved protein (DUF2132)
FR729_21010	COG0133	tryptophan synthase activity
FR729_21020	COG1278	Cold shock
FR729_21030	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
FR729_21040	COG0523	cobalamin synthesis protein
FR729_21045	COG0513	Belongs to the DEAD box helicase family
FR729_21065	COG2200	EAL domain
FR729_21070	COG1119	ATPase activity
FR729_21110	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
FR729_21115	COG0513	Belongs to the DEAD box helicase family
FR729_21130	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FR729_21140	COG1073	alpha beta
FR729_21145	COG1073	alpha beta
FR729_21160	COG0436	Aminotransferase
FR729_21230	COG0277	FAD linked oxidase domain protein
FR729_21230	COG0247	lactate metabolic process
FR729_21245	COG1024	Enoyl-CoA hydratase
FR729_21250	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FR729_21255	COG1960	acyl-CoA dehydrogenase activity
FR729_21265	COG0183	Belongs to the thiolase family
FR729_21280	COG1024	Enoyl-CoA hydratase
FR729_21285	COG1024	Enoyl-CoA hydratase
FR729_21295	COG1028	Short-chain dehydrogenase reductase Sdr
FR729_21300	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FR729_21305	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FR729_21310	COG1845	cytochrome c oxidase, subunit III
FR729_21315	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
FR729_21320	COG0109	protoheme IX farnesyltransferase activity
FR729_21325	COG0446	pyridine nucleotide-disulphide oxidoreductase
FR729_21325	COG1902	pentaerythritol trinitrate reductase activity
FR729_21340	COG1012	belongs to the aldehyde dehydrogenase family
FR729_21350	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FR729_21380	COG1126	abc transporter atp-binding protein
FR729_21385	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FR729_21390	COG4215	(ABC) transporter
FR729_21395	COG4160	amino acid transport
FR729_21465	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FR729_21470	COG2176	DNA-directed DNA polymerase activity
FR729_21475	COG0517	IMP dehydrogenase activity
FR729_21480	COG2186	Transcriptional regulator
FR729_21485	COG2186	Transcriptional regulator
FR729_21530	COG1917	Cupin 2, conserved barrel domain protein
FR729_21535	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FR729_21540	COG0800	Aldolase
FR729_21550	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FR729_21555	COG1028	Short-chain dehydrogenase reductase Sdr
FR729_21560	COG2847	Copper chaperone PCu(A)C
FR729_21615	COG3706	GGDEF domain
FR729_21625	COG0814	amino acid
FR729_21635	COG0243	molybdopterin cofactor binding
FR729_21665	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FR729_21665	COG1116	anion transmembrane transporter activity
FR729_21670	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FR729_21675	COG1116	anion transmembrane transporter activity
FR729_21680	COG2146	nitrite reductase [NAD(P)H] activity
FR729_21680	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FR729_21730	COG2815	serine threonine protein kinase
FR729_21730	COG0515	serine threonine protein kinase
FR729_21765	COG0631	protein serine/threonine phosphatase activity
FR729_21820	COG3501	Rhs element vgr protein
FR729_21835	COG0420	3'-5' exonuclease activity
FR729_21840	COG0419	ATPase involved in DNA repair
FR729_21850	COG3040	lipid binding
FR729_21860	COG1288	antiporter activity
FR729_21870	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
FR729_21885	COG2425	protein containing a von Willebrand factor type A (vWA) domain
FR729_21900	COG0583	DNA-binding transcription factor activity
FR729_21905	COG0277	FAD linked oxidase domain protein
FR729_21920	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FR729_21995	COG5001	Diguanylate cyclase
FR729_22005	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FR729_22010	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FR729_22020	COG2116	formate transmembrane transporter activity
FR729_22040	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
FR729_22080	COG3118	belongs to the thioredoxin family
FR729_22085	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FR729_22110	COG2271	Major facilitator Superfamily
FR729_22115	COG3851	Histidine kinase
FR729_22120	COG2197	response regulator
FR729_22130	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FR729_22135	COG0583	DNA-binding transcription factor activity
FR729_22160	COG0384	phenazine biosynthesis protein PhzF
FR729_22165	COG1794	racemase activity, acting on amino acids and derivatives
FR729_22195	COG1328	CTP reductase activity
FR729_22200	COG0602	queuosine metabolic process
FR729_22205	COG0534	Mate efflux family protein
FR729_22210	COG2207	Transcriptional regulator
FR729_22220	COG0189	ligase activity
FR729_22220	COG4067	protein conserved in archaea
FR729_22230	COG3111	PFAM Bacterial OB fold (BOF) protein
FR729_22240	COG0725	ABC transporter, periplasmic molybdate-binding protein
FR729_22245	COG4149	molybdate abc transporter
FR729_22250	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
FR729_22260	COG5001	Diguanylate cyclase
FR729_22260	COG2203	Gaf domain
FR729_22260	COG3706	GGDEF domain
FR729_22260	COG4251	negative regulation of phosphorylation
FR729_22280	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
FR729_22285	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
FR729_22310	COG3140	Belongs to the UPF0181 family
FR729_22325	COG0583	DNA-binding transcription factor activity
FR729_22415	COG0023	Translation Initiation Factor
FR729_22425	COG1181	Belongs to the D-alanine--D-alanine ligase family
FR729_22435	COG0045	succinate-CoA ligase (ADP-forming) activity
FR729_22435	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FR729_22435	COG1042	CoA-binding domain protein
FR729_22440	COG0583	DNA-binding transcription factor activity
FR729_22460	COG5002	protein histidine kinase activity
FR729_22460	COG3447	MASE1 domain protein
FR729_22460	COG5001	Diguanylate cyclase
FR729_22465	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
FR729_22470	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FR729_22475	COG1984	allophanate hydrolase subunit 2
FR729_22485	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
FR729_22490	COG4181	ATPase activity
FR729_22500	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FR729_22505	COG5001	Diguanylate cyclase
FR729_22505	COG3300	MHYT domain
FR729_22515	COG0484	heat shock protein binding
FR729_22540	COG4533	DNA binding
FR729_22550	COG2050	protein possibly involved in aromatic compounds catabolism
FR729_22565	COG2067	long-chain fatty acid transport protein
FR729_22570	COG2267	carboxylic ester hydrolase activity
FR729_22595	COG0737	Belongs to the 5'-nucleotidase family
FR729_22600	COG3593	DNA synthesis involved in DNA repair
FR729_22610	COG0583	DNA-binding transcription factor activity
FR729_22615	COG2116	formate transmembrane transporter activity
FR729_22620	COG2353	YceI-like domain
FR729_22625	COG3038	cytochrome b561
FR729_22645	COG0513	Belongs to the DEAD box helicase family
FR729_22650	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
FR729_22660	COG0840	transmembrane signaling receptor activity
FR729_22670	COG0546	phosphoglycolate phosphatase activity
FR729_22685	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FR729_22690	COG2759	Belongs to the formate--tetrahydrofolate ligase family
FR729_22695	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FR729_22710	COG2207	Transcriptional regulator
FR729_22715	COG1979	alcohol dehydrogenase
FR729_22725	COG1126	abc transporter atp-binding protein
FR729_22730	COG0765	amino acid transport
FR729_22735	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FR729_22740	COG0765	amino acid transport
FR729_22745	COG2199	diguanylate cyclase activity
FR729_22745	COG2200	EAL domain
FR729_22745	COG2203	Gaf domain
FR729_22760	COG1609	Transcriptional regulator
FR729_22765	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FR729_22765	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
FR729_22770	COG1105	Belongs to the carbohydrate kinase PfkB family
FR729_22775	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FR729_22775	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FR729_22775	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
FR729_22805	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FR729_22815	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FR729_22820	COG0509	glycine decarboxylation via glycine cleavage system
FR729_22830	COG0346	lactoylglutathione lyase activity
FR729_22845	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FR729_22850	COG0583	DNA-binding transcription factor activity
FR729_22855	COG0697	spore germination
FR729_22860	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FR729_22885	COG2176	DNA-directed DNA polymerase activity
FR729_22930	COG0242	peptide deformylase activity
FR729_22970	COG2239	Acts as a magnesium transporter
FR729_22990	COG0346	lactoylglutathione lyase activity
FR729_22995	COG1902	pentaerythritol trinitrate reductase activity
FR729_23015	COG5642	Protein of unknown function (DUF2384)
FR729_23020	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
FR729_23055	COG2076	Multidrug Resistance protein
FR729_23075	COG2962	Rard protein
FR729_23090	COG0835	chemotaxis
FR729_23090	COG0784	Response regulator, receiver
FR729_23100	COG2197	response regulator
FR729_23110	COG3706	GGDEF domain
FR729_23115	COG2197	response regulator
FR729_23120	COG5001	Diguanylate cyclase
FR729_23120	COG3300	MHYT domain
FR729_23125	COG0784	Response regulator, receiver
FR729_23125	COG2205	protein histidine kinase activity
FR729_23130	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
FR729_23150	COG0456	acetyltransferase
FR729_23150	COG1214	PFAM Peptidase M22, glycoprotease
FR729_23160	COG3069	C4-dicarboxylate transmembrane transporter activity
FR729_23185	COG3111	PFAM Bacterial OB fold (BOF) protein
FR729_23190	COG1597	lipid kinase activity
FR729_23195	COG0583	DNA-binding transcription factor activity
FR729_23200	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FR729_23230	COG0714	Associated with various cellular activities
FR729_23235	COG0641	radical SAM
FR729_23240	COG3119	arylsulfatase activity
FR729_23250	COG3119	arylsulfatase activity
FR729_23255	COG0745	RESPONSE REGULATOR receiver
FR729_23270	COG2205	protein histidine kinase activity
FR729_23270	COG2198	Histidine kinase
FR729_23270	COG0784	Response regulator, receiver
FR729_23275	COG1879	ABC-type sugar transport system periplasmic component
FR729_23280	COG1803	Methylglyoxal synthase
FR729_23285	COG0210	DNA helicase
FR729_23290	COG1289	transmembrane transporter activity
FR729_23325	COG1629	transport
FR729_23325	COG4771	TonB-dependent receptor
FR729_23335	COG0789	Transcriptional regulator
FR729_23340	COG4604	ABC transporter, ATP-binding protein
FR729_23345	COG4605	iron ion homeostasis
FR729_23350	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FR729_23355	COG4607	ABC-type enterochelin transport system periplasmic component
FR729_23365	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
FR729_23380	COG1609	Transcriptional regulator
FR729_23385	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FR729_23390	COG1879	ABC-type sugar transport system periplasmic component
FR729_23395	COG1172	Belongs to the binding-protein-dependent transport system permease family
FR729_23400	COG1129	ABC transporter
FR729_23405	COG1869	D-ribose catabolic process
FR729_23410	COG5001	Diguanylate cyclase
FR729_23465	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FR729_23475	COG0784	Response regulator, receiver
FR729_23475	COG2205	protein histidine kinase activity
FR729_23490	COG0330	HflC and HflK could
FR729_23505	COG4175	Glycine betaine
FR729_23505	COG0517	IMP dehydrogenase activity
FR729_23510	COG4176	ABC-type proline glycine betaine transport system permease component
FR729_23525	COG1012	belongs to the aldehyde dehydrogenase family
FR729_23530	COG1309	transcriptional regulator
FR729_23540	COG1028	Short-chain dehydrogenase reductase Sdr
FR729_23555	COG1024	Enoyl-CoA hydratase
FR729_23560	COG1960	acyl-CoA dehydrogenase activity
FR729_23570	COG0183	Belongs to the thiolase family
FR729_23580	COG1960	acyl-CoA dehydrogenase activity
FR729_23585	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FR729_23595	COG4770	biotin carboxylase activity
FR729_23610	COG3264	Mechanosensitive ion channel
FR729_23610	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
FR729_23620	COG0110	maltose O-acetyltransferase activity
FR729_23625	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FR729_23630	COG1271	oxidase subunit
FR729_23635	COG1294	oxidase, subunit
FR729_23650	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FR729_23660	COG3527	Alpha-acetolactate decarboxylase
FR729_23675	COG0500	methyltransferase
FR729_23705	COG1022	Amp-dependent synthetase and ligase
FR729_23735	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FR729_23740	COG1263	PTS System
FR729_23740	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FR729_23745	COG1486	melibiose metabolic process
FR729_23750	COG2188	Transcriptional regulator
FR729_23755	COG1320	monovalent cation:proton antiporter activity
FR729_23760	COG2212	antiporter activity
FR729_23775	COG1006	Multisubunit Na H antiporter MnhC subunit
FR729_23780	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FR729_23780	COG2111	Na H antiporter
FR729_23790	COG0589	response to stress
FR729_23795	COG4221	oxidoreductase activity
FR729_23800	COG0583	DNA-binding transcription factor activity
FR729_23810	COG2814	Major facilitator Superfamily
FR729_23875	COG1522	sequence-specific DNA binding
FR729_23910	COG0515	serine threonine protein kinase
FR729_23935	COG3501	Rhs element vgr protein
FR729_23975	COG0739	heme binding
FR729_23990	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FR729_24005	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FR729_24005	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FR729_24035	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
FR729_24045	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FR729_24045	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FR729_24060	COG4989	oxidoreductase activity
FR729_24075	COG0038	chloride channel
FR729_24095	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FR729_24115	COG2897	thiosulfate sulfurtransferase activity
FR729_24135	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FR729_24140	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FR729_24145	COG0840	transmembrane signaling receptor activity
FR729_24150	COG2814	Major facilitator Superfamily
FR729_24155	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FR729_24170	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FR729_24180	COG0840	transmembrane signaling receptor activity
FR729_24200	COG2195	Cleaves the N-terminal amino acid of tripeptides
FR729_24215	COG2197	response regulator
FR729_24220	COG3850	Histidine kinase
FR729_24225	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FR729_24235	COG0243	molybdopterin cofactor binding
FR729_24245	COG3005	denitrification pathway
FR729_24255	COG3243	poly(R)-hydroxyalkanoic acid synthase
FR729_24265	COG0183	Belongs to the thiolase family
FR729_24275	COG1280	lysine exporter protein (LysE YggA)
FR729_24285	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FR729_24290	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FR729_24340	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FR729_24345	COG1846	Transcriptional regulator
FR729_24350	COG2205	protein histidine kinase activity
FR729_24350	COG0784	Response regulator, receiver
FR729_24355	COG1879	ABC-type sugar transport system periplasmic component
FR729_24365	COG2827	Endonuclease containing a URI domain
FR729_24370	COG3132	Protein of unknown function, DUF480
FR729_24390	COG0784	Response regulator, receiver
FR729_24390	COG2205	protein histidine kinase activity
FR729_24390	COG5002	protein histidine kinase activity
FR729_24415	COG0583	DNA-binding transcription factor activity
FR729_24430	COG0531	amino acid
FR729_24445	COG2205	protein histidine kinase activity
FR729_24450	COG0745	RESPONSE REGULATOR receiver
FR729_24475	COG1566	PFAM secretion protein HlyD family protein
FR729_24480	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FR729_24485	COG2239	Acts as a magnesium transporter
FR729_24490	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
FR729_24495	COG0402	S-adenosylhomocysteine deaminase activity
FR729_24500	COG1418	mRNA catabolic process
FR729_24515	COG2814	Major facilitator Superfamily
FR729_24525	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FR729_24545	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FR729_24560	COG0745	RESPONSE REGULATOR receiver
FR729_24565	COG2205	protein histidine kinase activity
FR729_24575	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FR729_24580	COG2194	sulfuric ester hydrolase activity
FR729_24600	COG4667	esterase of the alpha-beta hydrolase superfamily
FR729_24605	COG1741	Belongs to the pirin family
FR729_24610	COG1278	Cold shock
FR729_24625	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FR729_24630	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FR729_24630	COG0678	peroxiredoxin activity
FR729_24640	COG1686	Belongs to the peptidase S11 family
FR729_24650	COG0625	glutathione transferase activity
FR729_24660	COG1621	beta-fructofuranosidase activity
FR729_24665	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FR729_24690	COG1028	Short-chain dehydrogenase reductase Sdr
FR729_24705	COG3746	phosphate-selective porin O and P
FR729_24725	COG0583	DNA-binding transcription factor activity
FR729_24730	COG2207	Transcriptional regulator
FR729_24730	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FR729_24735	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FR729_24765	COG0513	Belongs to the DEAD box helicase family
FR729_24775	COG0583	DNA-binding transcription factor activity