locus-tag	class	description
AL541_00005	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AL541_00015	COG2067	long-chain fatty acid transport protein
AL541_00025	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL541_00035	COG1505	serine-type exopeptidase activity
AL541_00040	COG0488	(ABC) transporter
AL541_00045	COG0589	response to stress
AL541_00050	COG2249	NAD(P)H dehydrogenase (quinone) activity
AL541_00070	COG0366	Alpha amylase catalytic
AL541_00075	COG0789	Transcriptional regulator
AL541_00080	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AL541_00090	COG4934	collagen metabolic process
AL541_00100	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AL541_00105	COG0583	DNA-binding transcription factor activity
AL541_00130	COG2610	gluconate transmembrane transporter activity
AL541_00135	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AL541_00140	COG3622	Belongs to the hyi family
AL541_00145	COG0235	Class ii aldolase
AL541_00150	COG3395	kinase activity
AL541_00155	COG2084	Dehydrogenase
AL541_00160	COG1349	DNA-binding transcription factor activity
AL541_00170	COG0747	negative chemotaxis
AL541_00175	COG4608	Belongs to the ABC transporter superfamily
AL541_00180	COG0444	Belongs to the ABC transporter superfamily
AL541_00185	COG0534	Mate efflux family protein
AL541_00190	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AL541_00195	COG0784	Response regulator, receiver
AL541_00195	COG0835	chemotaxis
AL541_00205	COG0748	coenzyme F420 binding
AL541_00210	COG3721	Heme iron utilization protein
AL541_00220	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
AL541_00225	COG0811	peptide transport
AL541_00230	COG0848	biopolymer transport protein
AL541_00240	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AL541_00245	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
AL541_00285	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AL541_00295	COG3217	Mosc domain protein beta barrel domain protein
AL541_00295	COG0633	Ferredoxin
AL541_00295	COG3217	Mosc domain protein beta barrel domain protein
AL541_00295	COG0633	Ferredoxin
AL541_00300	COG0401	homolog of Blt101
AL541_00310	COG0418	dihydroorotase activity
AL541_00315	COG2354	Protein conserved in bacteria
AL541_00325	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AL541_00330	COG4605	iron ion homeostasis
AL541_00335	COG4607	ABC-type enterochelin transport system periplasmic component
AL541_00340	COG4774	siderophore transport
AL541_00345	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AL541_00375	COG3833	ABC-type maltose transport systems, permease component
AL541_00380	COG1175	transmembrane transport
AL541_00390	COG3842	ATPase activity
AL541_00395	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AL541_00410	COG3206	protein involved in exopolysaccharide biosynthesis
AL541_00410	COG0489	protein tyrosine kinase activity
AL541_00455	COG1309	transcriptional regulator
AL541_00460	COG2130	NADP-dependent
AL541_00470	COG0753	catalase activity
AL541_00475	COG2084	Dehydrogenase
AL541_00505	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AL541_00510	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
AL541_00520	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AL541_00525	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AL541_00545	COG0583	DNA-binding transcription factor activity
AL541_00550	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AL541_00555	COG0569	domain protein
AL541_00565	COG5002	protein histidine kinase activity
AL541_00570	COG1132	(ABC) transporter
AL541_00575	COG4774	siderophore transport
AL541_00580	COG1120	ATPase activity
AL541_00585	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
AL541_00620	COG2197	response regulator
AL541_00635	COG0714	Associated with various cellular activities
AL541_00655	COG2304	oxidoreductase activity
AL541_00670	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AL541_00675	COG0581	inorganic phosphate transmembrane transporter activity
AL541_00680	COG0573	inorganic phosphate transmembrane transporter activity
AL541_00685	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AL541_00710	COG4771	TonB-dependent receptor
AL541_00715	COG1770	oligopeptidase
AL541_00720	COG0513	Belongs to the DEAD box helicase family
AL541_00730	COG1376	ErfK ybiS ycfS ynhG family protein
AL541_00730	COG1388	LysM domain
AL541_00735	COG0415	Belongs to the DNA photolyase family
AL541_00740	COG0789	Transcriptional regulator
AL541_00745	COG3272	Protein of unknown function (DUF1722)
AL541_00750	COG0813	purine-nucleoside phosphorylase activity
AL541_00765	COG3706	GGDEF domain
AL541_00775	COG1566	PFAM secretion protein HlyD family protein
AL541_00780	COG4720	Psort location CytoplasmicMembrane, score
AL541_00785	COG1122	ATPase activity
AL541_00805	COG0348	domain, Protein
AL541_00810	COG0437	4 iron, 4 sulfur cluster binding
AL541_00815	COG1247	-acetyltransferase
AL541_00835	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AL541_00840	COG0840	transmembrane signaling receptor activity
AL541_00845	COG1067	ATP-dependent peptidase activity
AL541_00855	COG4172	Belongs to the ABC transporter superfamily
AL541_00860	COG1505	serine-type exopeptidase activity
AL541_00865	COG0583	DNA-binding transcription factor activity
AL541_00870	COG1620	l-lactate permease
AL541_00875	COG1304	FMN binding
AL541_00885	COG0668	transmembrane transport
AL541_00920	COG1063	alcohol dehydrogenase
AL541_00925	COG0156	8-amino-7-oxononanoate synthase activity
AL541_00930	COG3300	MHYT domain
AL541_00930	COG5001	Diguanylate cyclase
AL541_00955	COG0745	RESPONSE REGULATOR receiver
AL541_00980	COG0346	lactoylglutathione lyase activity
AL541_01040	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AL541_01055	COG2204	response regulator
AL541_01080	COG1987	bacterial-type flagellum assembly
AL541_01090	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AL541_01105	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AL541_01115	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
AL541_01120	COG1516	flagellar protein fliS
AL541_01135	COG1580	Controls the rotational direction of flagella during chemotaxis
AL541_01140	COG1191	sigma factor activity
AL541_01145	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AL541_01150	COG1360	Flagellar Motor Protein
AL541_01190	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AL541_01195	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AL541_01215	COG2205	protein histidine kinase activity
AL541_01220	COG0745	RESPONSE REGULATOR receiver
AL541_01245	COG2814	Major facilitator Superfamily
AL541_01290	COG0628	permease
AL541_01295	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
AL541_01315	COG4628	conserved protein (DUF2132)
AL541_01320	COG0583	DNA-binding transcription factor activity
AL541_01345	COG1686	Belongs to the peptidase S11 family
AL541_01365	COG0415	Belongs to the DNA photolyase family
AL541_01370	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
AL541_01375	COG3397	chitin binding
AL541_01380	COG4667	esterase of the alpha-beta hydrolase superfamily
AL541_01385	COG2095	MarC family integral membrane protein
AL541_01405	COG0489	protein tyrosine kinase activity
AL541_01405	COG3206	protein involved in exopolysaccharide biosynthesis
AL541_01420	COG0583	DNA-binding transcription factor activity
AL541_01430	COG1301	dicarboxylic acid transport
AL541_01445	COG3339	Conserved Protein
AL541_01450	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AL541_01455	COG0700	Nucleoside recognition
AL541_01460	COG3366	ferrous iron transmembrane transporter activity
AL541_01475	COG0366	Alpha amylase catalytic
AL541_01480	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AL541_01485	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AL541_01490	COG1640	4-alpha-glucanotransferase
AL541_01495	COG0058	SHG alpha-glucan phosphorylase activity
AL541_01500	COG2909	trisaccharide binding
AL541_01515	COG1999	signal sequence binding
AL541_01520	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AL541_01520	COG1263	PTS System
AL541_01525	COG1162	GTPase activity
AL541_01530	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
AL541_01535	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
AL541_01555	COG2356	endonuclease I
AL541_01575	COG4580	involved in the transport of maltose and maltodextrins
AL541_01585	COG1760	l-serine dehydratase
AL541_01635	COG1609	Transcriptional regulator
AL541_01640	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AL541_01665	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AL541_01670	COG1609	Transcriptional regulator
AL541_01680	COG2814	Major facilitator Superfamily
AL541_01695	COG0739	heme binding
AL541_01705	COG0612	Peptidase, M16
AL541_01710	COG0840	transmembrane signaling receptor activity
AL541_01715	COG1120	ATPase activity
AL541_01720	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AL541_01725	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AL541_01730	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
AL541_01735	COG4772	TonB-dependent receptor
AL541_01760	COG4264	IucA IucC family
AL541_01765	COG0019	diaminopimelate decarboxylase activity
AL541_01770	COG1653	transport
AL541_01780	COG0745	RESPONSE REGULATOR receiver
AL541_01810	COG1136	(ABC) transporter
AL541_01860	COG1764	response to oxidative stress
AL541_01865	COG1846	Transcriptional regulator
AL541_01870	COG0450	alkyl hydroperoxide reductase
AL541_01875	COG3634	alkyl hydroperoxide reductase activity
AL541_01940	COG2258	MOSC domain
AL541_01945	COG0513	Belongs to the DEAD box helicase family
AL541_01955	COG1132	(ABC) transporter
AL541_01995	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AL541_02020	COG0259	pyridoxamine-phosphate oxidase activity
AL541_02065	COG4166	transmembrane transport
AL541_02085	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
AL541_02090	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AL541_02090	COG1263	PTS System
AL541_02095	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AL541_02100	COG3340	Belongs to the peptidase S51 family
AL541_02120	COG1444	tRNA N-acetyltransferase activity
AL541_02145	COG4608	Belongs to the ABC transporter superfamily
AL541_02150	COG0444	Belongs to the ABC transporter superfamily
AL541_02160	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AL541_02160	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
AL541_02185	COG0772	Belongs to the SEDS family
AL541_02195	COG1136	(ABC) transporter
AL541_02215	COG3275	phosphorelay sensor kinase activity
AL541_02220	COG3279	Response regulator of the LytR AlgR family
AL541_02225	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AL541_02250	COG0786	glutamate:sodium symporter activity
AL541_02260	COG1131	(ABC) transporter
AL541_02265	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL541_02270	COG0786	glutamate:sodium symporter activity
AL541_02280	COG0363	glucosamine-6-phosphate deaminase activity
AL541_02300	COG1741	Belongs to the pirin family
AL541_02305	COG2259	Doxx family
AL541_02315	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AL541_02315	COG2169	Transcriptional regulator
AL541_02320	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AL541_02330	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AL541_02355	COG0596	Alpha beta hydrolase
AL541_02370	COG3123	guanosine phosphorylase activity
AL541_02380	COG5001	Diguanylate cyclase
AL541_02385	COG0534	Mate efflux family protein
AL541_02390	COG0564	pseudouridine synthase activity
AL541_02405	COG0583	DNA-binding transcription factor activity
AL541_02410	COG0561	phosphatase activity
AL541_02420	COG2199	diguanylate cyclase activity
AL541_02435	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
AL541_02440	COG2162	N-hydroxyarylamine O-acetyltransferase activity
AL541_02445	COG0583	DNA-binding transcription factor activity
AL541_02450	COG2375	cellular response to nickel ion
AL541_02480	COG1357	PFAM Pentapeptide repeats (8 copies)
AL541_02485	COG3047	cAMP biosynthetic process
AL541_02495	COG2814	Major facilitator Superfamily
AL541_02545	COG3835	regulator
AL541_02550	COG2610	gluconate transmembrane transporter activity
AL541_02555	COG1929	Belongs to the glycerate kinase type-1 family
AL541_02560	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL541_02580	COG0456	acetyltransferase
AL541_02595	COG1028	Short-chain dehydrogenase reductase Sdr
AL541_02600	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AL541_02605	COG3005	denitrification pathway
AL541_02610	COG0243	molybdopterin cofactor binding
AL541_02630	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AL541_02635	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AL541_02640	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AL541_02645	COG1116	anion transmembrane transporter activity
AL541_02650	COG0351	phosphomethylpyrimidine kinase
AL541_02655	COG0312	modulator of DNA gyrase
AL541_02660	COG0312	modulator of DNA gyrase
AL541_02665	COG1901	pseudouridine methyltransferase
AL541_02725	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AL541_02735	COG0584	glycerophosphoryl diester phosphodiesterase
AL541_02740	COG0745	RESPONSE REGULATOR receiver
AL541_02760	COG0811	peptide transport
AL541_02765	COG0811	peptide transport
AL541_02770	COG0848	biopolymer transport protein
AL541_02820	COG0803	Belongs to the bacterial solute-binding protein 9 family
AL541_02825	COG1121	(ABC) transporter
AL541_02830	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AL541_02845	COG1770	oligopeptidase
AL541_02850	COG2814	Major facilitator Superfamily
AL541_02860	COG1166	arginine decarboxylase activity
AL541_02870	COG4067	protein conserved in archaea
AL541_02870	COG0189	ligase activity
AL541_02875	COG0189	ligase activity
AL541_02900	COG0583	DNA-binding transcription factor activity
AL541_02920	COG4191	Histidine kinase
AL541_02930	COG3706	GGDEF domain
AL541_02955	COG0579	oxidoreductase
AL541_02960	COG3179	chitinase
AL541_02980	COG1294	oxidase, subunit
AL541_02985	COG1271	oxidase subunit
AL541_02995	COG3033	Beta-eliminating lyase
AL541_03015	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AL541_03030	COG3706	GGDEF domain
AL541_03045	COG3706	GGDEF domain
AL541_03050	COG0415	Belongs to the DNA photolyase family
AL541_03055	COG3046	protein related to deoxyribodipyrimidine photolyase
AL541_03070	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AL541_03070	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AL541_03075	COG1765	OsmC-like protein
AL541_03080	COG0110	maltose O-acetyltransferase activity
AL541_03120	COG1011	Hydrolase
AL541_03135	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
AL541_03145	COG2067	long-chain fatty acid transport protein
AL541_03155	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL541_03160	COG0577	efflux transmembrane transporter activity
AL541_03160	COG1136	(ABC) transporter
AL541_03175	COG1309	transcriptional regulator
AL541_03180	COG3240	lipase activity
AL541_03210	COG1609	Transcriptional regulator
AL541_03230	COG1840	ABC-type Fe3 transport system, periplasmic component
AL541_03235	COG3842	ATPase activity
AL541_03260	COG2990	Protein conserved in bacteria
AL541_03270	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AL541_03275	COG2866	Carboxypeptidase
AL541_03285	COG0583	DNA-binding transcription factor activity
AL541_03300	COG1760	l-serine dehydratase
AL541_03320	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AL541_03325	COG1388	LysM domain
AL541_03325	COG0741	lytic transglycosylase activity
AL541_03345	COG1815	bacterial-type flagellum-dependent cell motility
AL541_03350	COG1558	bacterial-type flagellum-dependent cell motility
AL541_03355	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
AL541_03360	COG1749	Flagellar hook protein flgE
AL541_03365	COG4787	bacterial-type flagellum-dependent cell motility
AL541_03370	COG4786	Flagellar basal body rod
AL541_03375	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
AL541_03380	COG1706	bacterial-type flagellum-dependent cell motility
AL541_03390	COG1256	bacterial-type flagellum assembly
AL541_03390	COG4786	Flagellar basal body rod
AL541_03415	COG1304	FMN binding
AL541_03430	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AL541_03435	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AL541_03440	COG0459	protein refolding
AL541_03450	COG1280	lysine exporter protein (LysE YggA)
AL541_03470	COG1309	transcriptional regulator
AL541_03480	COG4303	Ethanolamine ammonia lyase large subunit
AL541_03485	COG4302	ethanolamine ammonia-lyase activity
AL541_03490	COG0531	amino acid
AL541_03495	COG2070	2-Nitropropane dioxygenase
AL541_03505	COG1349	DNA-binding transcription factor activity
AL541_03520	COG1335	isochorismatase
AL541_03530	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AL541_03555	COG0583	DNA-binding transcription factor activity
AL541_03570	COG3713	MltA-interacting MipA family protein
AL541_03575	COG3015	lipoprotein NlpE involved in copper resistance
AL541_03580	COG4175	Glycine betaine
AL541_03580	COG3448	diguanylate cyclase activity
AL541_03585	COG4176	ABC-type proline glycine betaine transport system permease component
AL541_03595	COG1342	Belongs to the UPF0251 family
AL541_03620	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AL541_03630	COG4948	Mandelate Racemase Muconate Lactonizing
AL541_03640	COG0583	DNA-binding transcription factor activity
AL541_03675	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AL541_03680	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AL541_03710	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AL541_03730	COG3842	ATPase activity
AL541_03760	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AL541_03780	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AL541_03785	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AL541_03790	COG2197	response regulator
AL541_03805	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
AL541_03810	COG0252	asparaginase activity
AL541_03820	COG0583	DNA-binding transcription factor activity
AL541_03835	COG3122	Protein conserved in bacteria
AL541_03840	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AL541_03845	COG1012	belongs to the aldehyde dehydrogenase family
AL541_03850	COG1522	sequence-specific DNA binding
AL541_03855	COG3608	succinylglutamate desuccinylase aspartoacylase
AL541_03860	COG0006	proline dipeptidase activity
AL541_03865	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL541_03875	COG1028	Short-chain dehydrogenase reductase Sdr
AL541_03885	COG1063	alcohol dehydrogenase
AL541_03890	COG1902	pentaerythritol trinitrate reductase activity
AL541_03905	COG0583	DNA-binding transcription factor activity
AL541_03915	COG0513	Belongs to the DEAD box helicase family
AL541_03945	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL541_03950	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AL541_03950	COG2207	Transcriptional regulator
AL541_03955	COG0583	DNA-binding transcription factor activity
AL541_03960	COG0300	oxidoreductase activity
AL541_03975	COG3746	phosphate-selective porin O and P
AL541_03990	COG1028	Short-chain dehydrogenase reductase Sdr
AL541_03995	COG1404	Belongs to the peptidase S8 family
AL541_04005	COG0583	DNA-binding transcription factor activity
AL541_04010	COG4771	TonB-dependent receptor
AL541_04030	COG1263	PTS System
AL541_04030	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AL541_04035	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AL541_04040	COG1621	beta-fructofuranosidase activity
AL541_04045	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AL541_04055	COG0625	glutathione transferase activity
AL541_04065	COG1686	Belongs to the peptidase S11 family
AL541_04080	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AL541_04095	COG1278	Cold shock
AL541_04100	COG1741	Belongs to the pirin family
AL541_04105	COG4667	esterase of the alpha-beta hydrolase superfamily
AL541_04125	COG2194	sulfuric ester hydrolase activity
AL541_04130	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AL541_04140	COG2205	protein histidine kinase activity
AL541_04145	COG0745	RESPONSE REGULATOR receiver
AL541_04160	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AL541_04180	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AL541_04190	COG2814	Major facilitator Superfamily
AL541_04205	COG1418	mRNA catabolic process
AL541_04210	COG0402	S-adenosylhomocysteine deaminase activity
AL541_04215	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
AL541_04220	COG2239	Acts as a magnesium transporter
AL541_04225	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AL541_04230	COG1566	PFAM secretion protein HlyD family protein
AL541_04255	COG0745	RESPONSE REGULATOR receiver
AL541_04260	COG2205	protein histidine kinase activity
AL541_04275	COG0531	amino acid
AL541_04290	COG0583	DNA-binding transcription factor activity
AL541_04310	COG5002	protein histidine kinase activity
AL541_04310	COG2205	protein histidine kinase activity
AL541_04310	COG0784	Response regulator, receiver
AL541_04330	COG3132	Protein of unknown function, DUF480
AL541_04335	COG2827	Endonuclease containing a URI domain
AL541_04345	COG1879	ABC-type sugar transport system periplasmic component
AL541_04350	COG2205	protein histidine kinase activity
AL541_04350	COG0784	Response regulator, receiver
AL541_04355	COG1846	Transcriptional regulator
AL541_04410	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AL541_04415	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AL541_04425	COG1280	lysine exporter protein (LysE YggA)
AL541_04435	COG0183	Belongs to the thiolase family
AL541_04445	COG3243	poly(R)-hydroxyalkanoic acid synthase
AL541_04455	COG3005	denitrification pathway
AL541_04465	COG0243	molybdopterin cofactor binding
AL541_04475	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AL541_04480	COG3850	Histidine kinase
AL541_04485	COG2197	response regulator
AL541_04500	COG2195	Cleaves the N-terminal amino acid of tripeptides
AL541_04520	COG0840	transmembrane signaling receptor activity
AL541_04530	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AL541_04545	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AL541_04550	COG2814	Major facilitator Superfamily
AL541_04560	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AL541_04565	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AL541_04585	COG2897	thiosulfate sulfurtransferase activity
AL541_04620	COG0038	chloride channel
AL541_04635	COG4989	oxidoreductase activity
AL541_04650	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AL541_04650	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AL541_04680	COG3537	Alpha-1,2-mannosidase
AL541_04685	COG3537	Alpha-1,2-mannosidase
AL541_04695	COG3537	Alpha-1,2-mannosidase
AL541_04700	COG3537	Alpha-1,2-mannosidase
AL541_04705	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AL541_04720	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AL541_04720	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL541_04720	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AL541_04725	COG2207	Transcriptional regulator
AL541_04735	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AL541_04740	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AL541_04765	COG0739	heme binding
AL541_04790	COG2204	response regulator
AL541_04805	COG3501	Rhs element vgr protein
AL541_04830	COG0515	serine threonine protein kinase
AL541_04865	COG1522	sequence-specific DNA binding
AL541_04930	COG2814	Major facilitator Superfamily
AL541_04940	COG0583	DNA-binding transcription factor activity
AL541_04945	COG4221	oxidoreductase activity
AL541_04950	COG0589	response to stress
AL541_04960	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AL541_04960	COG2111	Na H antiporter
AL541_04980	COG2212	antiporter activity
AL541_04985	COG1320	monovalent cation:proton antiporter activity
AL541_04990	COG2188	Transcriptional regulator
AL541_04995	COG1486	melibiose metabolic process
AL541_05000	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AL541_05000	COG1263	PTS System
AL541_05005	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AL541_05035	COG1022	Amp-dependent synthetase and ligase
AL541_05065	COG0500	methyltransferase
AL541_05095	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AL541_05110	COG3527	Alpha-acetolactate decarboxylase
AL541_05120	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AL541_05135	COG1294	oxidase, subunit
AL541_05140	COG1271	oxidase subunit
AL541_05145	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL541_05150	COG0110	maltose O-acetyltransferase activity
AL541_05160	COG3264	Mechanosensitive ion channel
AL541_05160	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
AL541_05185	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AL541_05190	COG1960	acyl-CoA dehydrogenase activity
AL541_05200	COG0183	Belongs to the thiolase family
AL541_05210	COG1960	acyl-CoA dehydrogenase activity
AL541_05215	COG1024	Enoyl-CoA hydratase
AL541_05230	COG1028	Short-chain dehydrogenase reductase Sdr
AL541_05235	COG3706	GGDEF domain
AL541_05235	COG0745	RESPONSE REGULATOR receiver
AL541_05240	COG1309	transcriptional regulator
AL541_05245	COG1012	belongs to the aldehyde dehydrogenase family
AL541_05260	COG4176	ABC-type proline glycine betaine transport system permease component
AL541_05265	COG0517	IMP dehydrogenase activity
AL541_05265	COG4175	Glycine betaine
AL541_05280	COG0330	HflC and HflK could
AL541_05295	COG2205	protein histidine kinase activity
AL541_05295	COG0784	Response regulator, receiver
AL541_05305	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AL541_05360	COG5001	Diguanylate cyclase
AL541_05365	COG1869	D-ribose catabolic process
AL541_05370	COG1129	ABC transporter
AL541_05375	COG1172	Belongs to the binding-protein-dependent transport system permease family
AL541_05380	COG1879	ABC-type sugar transport system periplasmic component
AL541_05385	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AL541_05390	COG1609	Transcriptional regulator
AL541_05405	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
AL541_05415	COG4607	ABC-type enterochelin transport system periplasmic component
AL541_05420	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AL541_05425	COG4605	iron ion homeostasis
AL541_05430	COG4604	ABC transporter, ATP-binding protein
AL541_05435	COG0789	Transcriptional regulator
AL541_05445	COG4771	TonB-dependent receptor
AL541_05445	COG1629	transport
AL541_05480	COG1289	transmembrane transporter activity
AL541_05485	COG0210	DNA helicase
AL541_05490	COG1803	Methylglyoxal synthase
AL541_05495	COG1879	ABC-type sugar transport system periplasmic component
AL541_05500	COG2205	protein histidine kinase activity
AL541_05500	COG0784	Response regulator, receiver
AL541_05500	COG2198	Histidine kinase
AL541_05515	COG0745	RESPONSE REGULATOR receiver
AL541_05520	COG3119	arylsulfatase activity
AL541_05530	COG3119	arylsulfatase activity
AL541_05535	COG0641	radical SAM
AL541_05540	COG0714	Associated with various cellular activities
AL541_05570	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AL541_05575	COG0583	DNA-binding transcription factor activity
AL541_05580	COG1597	lipid kinase activity
AL541_05585	COG3111	PFAM Bacterial OB fold (BOF) protein
AL541_05610	COG3069	C4-dicarboxylate transmembrane transporter activity
AL541_05620	COG0456	acetyltransferase
AL541_05620	COG1214	PFAM Peptidase M22, glycoprotease
AL541_05640	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
AL541_05645	COG2205	protein histidine kinase activity
AL541_05645	COG0784	Response regulator, receiver
AL541_05650	COG3300	MHYT domain
AL541_05650	COG5001	Diguanylate cyclase
AL541_05655	COG2197	response regulator
AL541_05660	COG3706	GGDEF domain
AL541_05670	COG2197	response regulator
AL541_05680	COG0835	chemotaxis
AL541_05680	COG0784	Response regulator, receiver
AL541_05695	COG2962	Rard protein
AL541_05715	COG2076	Multidrug Resistance protein
AL541_05745	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
AL541_05745	COG0069	glutamate synthase activity
AL541_05750	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
AL541_05765	COG2755	lipolytic protein G-D-S-L family
AL541_05765	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AL541_05775	COG1902	pentaerythritol trinitrate reductase activity
AL541_05780	COG0346	lactoylglutathione lyase activity
AL541_05800	COG2239	Acts as a magnesium transporter
AL541_05835	COG0242	peptide deformylase activity
AL541_05880	COG2176	DNA-directed DNA polymerase activity
AL541_05935	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AL541_05940	COG0697	spore germination
AL541_05945	COG0583	DNA-binding transcription factor activity
AL541_05950	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AL541_05960	COG0346	lactoylglutathione lyase activity
AL541_05970	COG0509	glycine decarboxylation via glycine cleavage system
AL541_05975	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AL541_05985	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AL541_06015	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AL541_06015	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
AL541_06015	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AL541_06020	COG1105	Belongs to the carbohydrate kinase PfkB family
AL541_06025	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL541_06025	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL541_06030	COG1609	Transcriptional regulator
AL541_06045	COG2203	Gaf domain
AL541_06045	COG2200	EAL domain
AL541_06045	COG2199	diguanylate cyclase activity
AL541_06050	COG0765	amino acid transport
AL541_06055	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL541_06060	COG0765	amino acid transport
AL541_06065	COG1126	abc transporter atp-binding protein
AL541_06075	COG1979	alcohol dehydrogenase
AL541_06080	COG2207	Transcriptional regulator
AL541_06095	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AL541_06100	COG2759	Belongs to the formate--tetrahydrofolate ligase family
AL541_06105	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AL541_06120	COG0546	phosphoglycolate phosphatase activity
AL541_06140	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
AL541_06145	COG0513	Belongs to the DEAD box helicase family
AL541_06165	COG3038	cytochrome b561
AL541_06170	COG2353	YceI-like domain
AL541_06175	COG2116	formate transmembrane transporter activity
AL541_06180	COG0583	DNA-binding transcription factor activity
AL541_06190	COG3593	DNA synthesis involved in DNA repair
AL541_06195	COG0737	Belongs to the 5'-nucleotidase family
AL541_06220	COG2267	carboxylic ester hydrolase activity
AL541_06225	COG2067	long-chain fatty acid transport protein
AL541_06240	COG2050	protein possibly involved in aromatic compounds catabolism
AL541_06250	COG4533	DNA binding
AL541_06285	COG5001	Diguanylate cyclase
AL541_06285	COG3300	MHYT domain
AL541_06290	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AL541_06300	COG4181	ATPase activity
AL541_06305	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
AL541_06315	COG1984	allophanate hydrolase subunit 2
AL541_06320	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
AL541_06325	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
AL541_06330	COG5001	Diguanylate cyclase
AL541_06330	COG5002	protein histidine kinase activity
AL541_06330	COG3447	MASE1 domain protein
AL541_06350	COG0583	DNA-binding transcription factor activity
AL541_06355	COG1042	CoA-binding domain protein
AL541_06355	COG0045	succinate-CoA ligase (ADP-forming) activity
AL541_06355	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AL541_06365	COG1181	Belongs to the D-alanine--D-alanine ligase family
AL541_06375	COG0023	Translation Initiation Factor
AL541_06535	COG3140	Belongs to the UPF0181 family
AL541_06560	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
AL541_06565	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AL541_06580	COG0745	RESPONSE REGULATOR receiver
AL541_06580	COG3706	GGDEF domain
AL541_06585	COG2203	Gaf domain
AL541_06585	COG3706	GGDEF domain
AL541_06585	COG4251	negative regulation of phosphorylation
AL541_06585	COG5001	Diguanylate cyclase
AL541_06595	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
AL541_06600	COG4149	molybdate abc transporter
AL541_06605	COG0725	ABC transporter, periplasmic molybdate-binding protein
AL541_06615	COG3111	PFAM Bacterial OB fold (BOF) protein
AL541_06625	COG0189	ligase activity
AL541_06625	COG4067	protein conserved in archaea
AL541_06635	COG2207	Transcriptional regulator
AL541_06640	COG0534	Mate efflux family protein
AL541_06645	COG0602	queuosine metabolic process
AL541_06650	COG1328	CTP reductase activity
AL541_06685	COG1794	racemase activity, acting on amino acids and derivatives
AL541_06690	COG0384	phenazine biosynthesis protein PhzF
AL541_06705	COG0243	molybdopterin cofactor binding
AL541_06715	COG0583	DNA-binding transcription factor activity
AL541_06720	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AL541_06730	COG2197	response regulator
AL541_06735	COG3851	Histidine kinase
AL541_06740	COG2271	Major facilitator Superfamily
AL541_06765	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AL541_06770	COG3118	belongs to the thioredoxin family
AL541_06775	COG2814	Major facilitator Superfamily
AL541_06810	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
AL541_06830	COG2116	formate transmembrane transporter activity
AL541_06835	COG2146	nitrite reductase [NAD(P)H] activity
AL541_06840	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AL541_06845	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AL541_06870	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AL541_06925	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AL541_06940	COG0277	FAD linked oxidase domain protein
AL541_06945	COG0583	DNA-binding transcription factor activity
AL541_06960	COG2425	protein containing a von Willebrand factor type A (vWA) domain
AL541_06975	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
AL541_06985	COG1288	antiporter activity
AL541_06995	COG3040	lipid binding
AL541_07005	COG0419	ATPase involved in DNA repair
AL541_07010	COG0420	3'-5' exonuclease activity
AL541_07025	COG3501	Rhs element vgr protein
AL541_07080	COG0631	protein serine/threonine phosphatase activity
AL541_07115	COG0515	serine threonine protein kinase
AL541_07115	COG2815	serine threonine protein kinase
AL541_07165	COG2146	nitrite reductase [NAD(P)H] activity
AL541_07165	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AL541_07170	COG1116	anion transmembrane transporter activity
AL541_07175	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AL541_07180	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AL541_07180	COG1116	anion transmembrane transporter activity
AL541_07210	COG0243	molybdopterin cofactor binding
AL541_07220	COG0814	amino acid
AL541_07230	COG3706	GGDEF domain
AL541_07295	COG2847	Copper chaperone PCu(A)C
AL541_07300	COG1028	Short-chain dehydrogenase reductase Sdr
AL541_07305	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
AL541_07315	COG0800	Aldolase
AL541_07320	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AL541_07325	COG1917	Cupin 2, conserved barrel domain protein
AL541_07370	COG2186	Transcriptional regulator
AL541_07375	COG2186	Transcriptional regulator
AL541_07380	COG0517	IMP dehydrogenase activity
AL541_07385	COG2176	DNA-directed DNA polymerase activity
AL541_07390	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AL541_07455	COG4160	amino acid transport
AL541_07460	COG4215	(ABC) transporter
AL541_07465	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL541_07470	COG1126	abc transporter atp-binding protein
AL541_07500	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AL541_07510	COG1012	belongs to the aldehyde dehydrogenase family
AL541_07525	COG0446	pyridine nucleotide-disulphide oxidoreductase
AL541_07525	COG1902	pentaerythritol trinitrate reductase activity
AL541_07530	COG0109	protoheme IX farnesyltransferase activity
AL541_07535	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AL541_07540	COG1845	cytochrome c oxidase, subunit III
AL541_07545	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AL541_07550	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AL541_07555	COG1028	Short-chain dehydrogenase reductase Sdr
AL541_07565	COG1024	Enoyl-CoA hydratase
AL541_07570	COG1024	Enoyl-CoA hydratase
AL541_07585	COG0183	Belongs to the thiolase family
AL541_07595	COG1960	acyl-CoA dehydrogenase activity
AL541_07600	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AL541_07605	COG1024	Enoyl-CoA hydratase
AL541_07630	COG2095	MarC family integral membrane protein
AL541_07640	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AL541_07650	COG0523	cobalamin synthesis protein
AL541_07660	COG0739	heme binding
AL541_07665	COG2988	succinylglutamate desuccinylase activity
AL541_07670	COG0523	cobalamin synthesis protein
AL541_07680	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AL541_07685	COG0735	belongs to the Fur family
AL541_07700	COG0730	response to heat
AL541_07715	COG1073	alpha beta
AL541_07720	COG1073	alpha beta
AL541_07730	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AL541_07745	COG0513	Belongs to the DEAD box helicase family
AL541_07750	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
AL541_07765	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AL541_07785	COG1119	ATPase activity
AL541_07790	COG2200	EAL domain
AL541_07810	COG0513	Belongs to the DEAD box helicase family
AL541_07815	COG0523	cobalamin synthesis protein
AL541_07825	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
AL541_07835	COG1278	Cold shock
AL541_07845	COG0133	tryptophan synthase activity
AL541_07855	COG4628	conserved protein (DUF2132)
AL541_07860	COG0513	Belongs to the DEAD box helicase family
AL541_07865	COG2814	Major facilitator Superfamily
AL541_07880	COG3530	Putative quorum-sensing-regulated virulence factor
AL541_07905	COG3186	Phenylalanine-4-hydroxylase
AL541_07910	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AL541_07915	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AL541_07935	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
AL541_07940	COG1454	alcohol dehydrogenase
AL541_07945	COG2133	pyrroloquinoline quinone binding
AL541_07950	COG1619	proteins homologs of microcin C7 resistance protein MccF
AL541_07960	COG0783	Belongs to the Dps family
AL541_07965	COG0840	transmembrane signaling receptor activity
AL541_07990	COG0784	Response regulator, receiver
AL541_07990	COG2205	protein histidine kinase activity
AL541_07995	COG1538	Outer membrane efflux protein
AL541_08005	COG1132	(ABC) transporter
AL541_08020	COG2199	diguanylate cyclase activity
AL541_08025	COG3036	rescue of stalled ribosome
AL541_08030	COG1278	Cold shock
AL541_08060	COG0545	Peptidyl-prolyl cis-trans isomerase
AL541_08065	COG0109	protoheme IX farnesyltransferase activity
AL541_08070	COG1612	heme a metabolic process
AL541_08090	COG1845	cytochrome c oxidase, subunit III
AL541_08095	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
AL541_08105	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AL541_08110	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AL541_08120	COG1280	lysine exporter protein (LysE YggA)
AL541_08140	COG0179	Fumarylacetoacetate (FAA) hydrolase
AL541_08155	COG0697	spore germination
AL541_08175	COG2814	Major facilitator Superfamily
AL541_08180	COG0583	DNA-binding transcription factor activity
AL541_08185	COG5001	Diguanylate cyclase
AL541_08190	COG0739	heme binding
AL541_08230	COG0814	amino acid
AL541_08255	COG4989	oxidoreductase activity
AL541_08280	COG1733	regulation of RNA biosynthetic process
AL541_08295	COG0798	PFAM Bile acid sodium symporter
AL541_08305	COG1881	PFAM PEBP family protein
AL541_08320	COG1131	(ABC) transporter
AL541_08325	COG0842	Transport permease protein
AL541_08335	COG3383	formate dehydrogenase (NAD+) activity
AL541_08355	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AL541_08405	COG1494	fructose-1,6-bisphosphatase
AL541_08415	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AL541_08420	COG1575	Belongs to the MenA family. Type 1 subfamily
AL541_08425	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
AL541_08430	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
AL541_08440	COG1609	Transcriptional regulator
AL541_08445	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AL541_08455	COG0254	rRNA binding
AL541_08465	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AL541_08470	COG0088	Forms part of the polypeptide exit tunnel
AL541_08480	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AL541_08485	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AL541_08490	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AL541_08495	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AL541_08505	COG0255	Belongs to the universal ribosomal protein uL29 family
AL541_08510	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AL541_08520	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AL541_08525	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AL541_08535	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AL541_08540	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AL541_08555	COG1841	ribosomal large subunit assembly
AL541_08565	COG0201	protein transport
AL541_08575	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AL541_08580	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AL541_08590	COG0202	RNA polymerase activity
AL541_08595	COG0203	ribosomal protein L17
AL541_08605	COG0545	Peptidyl-prolyl cis-trans isomerase
AL541_08615	COG2153	protein acetylation
AL541_08620	COG0513	Belongs to the DEAD box helicase family
AL541_08635	COG1648	precorrin-2 dehydrogenase activity
AL541_08635	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AL541_08640	COG0175	sulfate reduction
AL541_08645	COG2895	sulfate adenylyltransferase (ATP) activity
AL541_08650	COG3273	potassium ion transport
AL541_08650	COG0471	metal ion transport
AL541_08655	COG0529	Catalyzes the synthesis of activated sulfate
AL541_08675	COG4181	ATPase activity
AL541_08690	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
AL541_08700	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AL541_08705	COG0729	surface antigen
AL541_08710	COG2911	Protein conserved in bacteria
AL541_08715	COG2105	PFAM AIG2 family protein
AL541_08725	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AL541_08730	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
AL541_08740	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AL541_08745	COG0163	prenyltransferase activity
AL541_08750	COG4143	(ABC) transporter
AL541_08755	COG1178	ABC-type Fe3 transport system permease component
AL541_08760	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
AL541_08765	COG0583	DNA-binding transcription factor activity
AL541_08770	COG1902	pentaerythritol trinitrate reductase activity
AL541_08815	COG0142	geranyltranstransferase activity
AL541_08820	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AL541_08830	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AL541_08835	COG2966	Psort location CytoplasmicMembrane, score
AL541_08845	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AL541_08850	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AL541_08855	COG2967	ApaG domain
AL541_08860	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AL541_08865	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AL541_08870	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AL541_08875	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
AL541_08880	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
AL541_08900	COG0473	3-isopropylmalate dehydrogenase activity
AL541_08905	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AL541_08930	COG0583	DNA-binding transcription factor activity
AL541_08935	COG1022	Amp-dependent synthetase and ligase
AL541_08940	COG0028	Belongs to the TPP enzyme family
AL541_08945	COG0440	acetolactate synthase activity
AL541_08950	COG3706	GGDEF domain
AL541_08960	COG0469	pyruvate kinase activity
AL541_08965	COG1349	DNA-binding transcription factor activity
AL541_08970	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AL541_08980	COG2376	Dihydroxyacetone kinase
AL541_08985	COG1461	Dihydroxyacetone kinase
AL541_09000	COG3722	fumarate hydratase activity
AL541_09010	COG2213	PTS system mannitol-specific
AL541_09010	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL541_09085	COG3550	peptidyl-serine autophosphorylation
AL541_09110	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AL541_09120	COG3550	peptidyl-serine autophosphorylation
AL541_09135	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AL541_09140	COG0358	DNA primase activity
AL541_09145	COG1610	YqeY-like protein
AL541_09150	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AL541_09155	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AL541_09160	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AL541_09165	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
AL541_09170	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AL541_09175	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AL541_09180	COG1968	undecaprenyl-diphosphatase activity
AL541_09190	COG3267	Type II secretory pathway component ExeA
AL541_09190	COG3409	Peptidoglycan-binding domain 1 protein
AL541_09200	COG0405	Gamma-glutamyltransferase
AL541_09205	COG4991	sh3 domain protein
AL541_09210	COG0306	phosphate transporter
AL541_09215	COG1392	Phosphate transport regulator
AL541_09220	COG3025	triphosphatase activity
AL541_09235	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
AL541_09240	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
AL541_09240	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
AL541_09245	COG1538	Outer membrane efflux protein
AL541_09250	COG0494	nUDIX hydrolase
AL541_09255	COG3151	Protein conserved in bacteria
AL541_09265	COG3150	esterase
AL541_09270	COG0187	DNA topoisomerase II activity
AL541_09275	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AL541_09280	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AL541_09285	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AL541_09290	COG3105	Protein conserved in bacteria
AL541_09300	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AL541_09315	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AL541_09320	COG0723	plastoquinol--plastocyanin reductase activity
AL541_09325	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AL541_09330	COG2857	Cytochrome c1
AL541_09335	COG0625	glutathione transferase activity
AL541_09340	COG2969	positive regulation of protein catabolic process
AL541_09345	COG2823	Periplasmic or secreted lipoprotein
AL541_09350	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
AL541_09365	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AL541_09385	COG3116	cell division
AL541_09390	COG0768	penicillin binding
AL541_09395	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AL541_09400	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AL541_09405	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AL541_09410	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AL541_09415	COG0772	Belongs to the SEDS family
AL541_09430	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AL541_09435	COG0849	cell division
AL541_09440	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AL541_09445	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
AL541_09455	COG0653	protein targeting
AL541_09460	COG0494	nUDIX hydrolase
AL541_09470	COG0505	Belongs to the CarA family
AL541_09475	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AL541_09490	COG0730	response to heat
AL541_09495	COG0583	DNA-binding transcription factor activity
AL541_09500	COG2860	membrane
AL541_09515	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AL541_09525	COG0493	'glutamate synthase
AL541_09530	COG0069	glutamate synthase activity
AL541_09530	COG0070	glutamate synthase
AL541_09530	COG0067	glutamate synthase
AL541_09540	COG0069	glutamate synthase activity
AL541_09540	COG0067	glutamate synthase
AL541_09540	COG0070	glutamate synthase
AL541_09545	COG1242	4 iron, 4 sulfur cluster binding
AL541_09550	COG3706	GGDEF domain
AL541_09550	COG4251	negative regulation of phosphorylation
AL541_09550	COG5001	Diguanylate cyclase
AL541_09550	COG2203	Gaf domain
AL541_09555	COG5002	protein histidine kinase activity
AL541_09555	COG0784	Response regulator, receiver
AL541_09555	COG2198	Histidine kinase
AL541_09565	COG0745	RESPONSE REGULATOR receiver
AL541_09580	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AL541_09600	COG0083	homoserine kinase activity
AL541_09605	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AL541_09615	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
AL541_09620	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
AL541_09630	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AL541_09645	COG1115	amino acid carrier protein
AL541_09650	COG3022	response to hydroperoxide
AL541_09655	COG0513	Belongs to the DEAD box helicase family
AL541_09660	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
AL541_09670	COG0716	FMN binding
AL541_09680	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AL541_09685	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AL541_09700	COG2204	response regulator
AL541_09710	COG0667	Aldo Keto reductase
AL541_09735	COG0730	response to heat
AL541_09745	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AL541_09755	COG1283	sodium-dependent phosphate transmembrane transporter activity
AL541_09760	COG0583	DNA-binding transcription factor activity
AL541_09765	COG0640	Transcriptional regulator
AL541_09770	COG0268	Binds directly to 16S ribosomal RNA
AL541_09775	COG0728	peptidoglycan biosynthetic process
AL541_09780	COG0196	riboflavin kinase activity
AL541_09795	COG1047	Peptidyl-prolyl cis-trans
AL541_09800	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
AL541_09810	COG3279	Response regulator of the LytR AlgR family
AL541_09815	COG3275	phosphorelay sensor kinase activity
AL541_09820	COG1966	Carbon starvation protein
AL541_09840	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
AL541_09845	COG1472	Belongs to the glycosyl hydrolase 3 family
AL541_09850	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AL541_09855	COG0287	Prephenate dehydrogenase
AL541_09855	COG1605	Chorismate mutase
AL541_09860	COG0739	heme binding
AL541_09870	COG0488	(ABC) transporter
AL541_09880	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
AL541_09885	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
AL541_09890	COG1605	Chorismate mutase
AL541_09890	COG0077	Prephenate dehydratase
AL541_09895	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AL541_09905	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AL541_09910	COG0564	pseudouridine synthase activity
AL541_09920	COG0542	response to heat
AL541_09985	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AL541_09995	COG2974	May be involved in recombination
AL541_10005	COG0745	RESPONSE REGULATOR receiver
AL541_10010	COG5002	protein histidine kinase activity
AL541_10020	COG0248	Ppx GppA phosphatase
AL541_10025	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
AL541_10030	COG0573	inorganic phosphate transmembrane transporter activity
AL541_10035	COG0581	inorganic phosphate transmembrane transporter activity
AL541_10040	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AL541_10045	COG0704	Plays a role in the regulation of phosphate uptake
AL541_10055	COG3142	Participates in the control of copper homeostasis
AL541_10060	COG0450	alkyl hydroperoxide reductase
AL541_10065	COG0583	DNA-binding transcription factor activity
AL541_10070	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AL541_10080	COG0517	IMP dehydrogenase activity
AL541_10090	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AL541_10100	COG1862	Preprotein translocase
AL541_10105	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AL541_10110	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AL541_10125	COG0483	inositol monophosphate 1-phosphatase activity
AL541_10130	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
AL541_10140	COG1104	cysteine desulfurase activity
AL541_10145	COG0822	iron-sulfur transferase activity
AL541_10160	COG0443	Heat shock 70 kDa protein
AL541_10165	COG0633	Ferredoxin
AL541_10170	COG2975	iron-sulfur cluster assembly
AL541_10180	COG0105	UTP biosynthetic process
AL541_10195	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
AL541_10200	COG0124	histidyl-tRNA synthetase
AL541_10205	COG2976	Protein conserved in bacteria
AL541_10210	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AL541_10215	COG1160	GTP binding
AL541_10235	COG0516	GMP reductase activity
AL541_10235	COG0517	IMP dehydrogenase activity
AL541_10245	COG1757	Na H antiporter
AL541_10255	COG1584	GPR1 FUN34 yaaH family protein
AL541_10260	COG1115	amino acid carrier protein
AL541_10275	COG2873	o-acetylhomoserine
AL541_10280	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AL541_10300	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AL541_10300	COG3153	acetyltransferase
AL541_10305	COG0583	DNA-binding transcription factor activity
AL541_10330	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
AL541_10335	COG2867	negative regulation of translational initiation
AL541_10340	COG2914	Belongs to the UPF0125 (RnfH) family
AL541_10345	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AL541_10355	COG0497	DNA recombination
AL541_10365	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AL541_10370	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AL541_10375	COG1301	dicarboxylic acid transport
AL541_10385	COG0484	heat shock protein binding
AL541_10415	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
AL541_10420	COG0590	tRNA wobble adenosine to inosine editing
AL541_10430	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
AL541_10435	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AL541_10435	COG0047	phosphoribosylformylglycinamidine synthase activity
AL541_10465	COG2195	Cleaves the N-terminal amino acid of tripeptides
AL541_10470	COG2252	PERMEase
AL541_10475	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
AL541_10490	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AL541_10495	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AL541_10500	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AL541_10505	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AL541_10505	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AL541_10530	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
AL541_10535	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AL541_10540	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AL541_10545	COG0142	geranyltranstransferase activity
AL541_10550	COG1722	exodeoxyribonuclease VII activity
AL541_10555	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AL541_10565	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AL541_10565	COG0301	tRNA thio-modification
AL541_10570	COG0583	DNA-binding transcription factor activity
AL541_10580	COG2363	Small membrane protein
AL541_10590	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AL541_10595	COG1611	Belongs to the LOG family
AL541_10600	COG3706	GGDEF domain
AL541_10600	COG0745	RESPONSE REGULATOR receiver
AL541_10610	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AL541_10610	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AL541_10620	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
AL541_10625	COG1464	Belongs to the NlpA lipoprotein family
AL541_10630	COG2011	ABC-type metal ion transport system permease component
AL541_10635	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AL541_10640	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AL541_10650	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AL541_10650	COG1263	PTS System
AL541_10655	COG0366	Alpha amylase catalytic
AL541_10670	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AL541_10675	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AL541_10680	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AL541_10685	COG0321	lipoyl(octanoyl) transferase activity
AL541_10695	COG1686	Belongs to the peptidase S11 family
AL541_10700	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AL541_10705	COG0772	Belongs to the SEDS family
AL541_10710	COG0768	penicillin binding
AL541_10715	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AL541_10720	COG0799	negative regulation of ribosome biogenesis
AL541_10725	COG1466	dna polymerase III delta subunit
AL541_10730	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
AL541_10735	COG0495	leucyl-tRNA aminoacylation
AL541_10740	COG2888	peptidyl-tyrosine sulfation
AL541_10745	COG0815	Transfers the fatty acyl group on membrane lipoproteins
AL541_10750	COG4535	Mg2 and Co2 transporter CorC
AL541_10755	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AL541_10760	COG1702	phosphate starvation-inducible protein PhoH
AL541_10765	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AL541_10775	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AL541_10885	COG0012	GTP binding
AL541_10890	COG0193	aminoacyl-tRNA hydrolase activity
AL541_10895	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AL541_10900	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AL541_10905	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
AL541_10910	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
AL541_10920	COG2890	protein-(glutamine-N5) methyltransferase activity
AL541_10925	COG3094	Invasion gene expression up-regulator, SirB
AL541_10930	COG2912	Transglutaminase-like superfamily
AL541_10935	COG2877	3-deoxy-8-phosphooctulonate synthase activity
AL541_10940	COG0737	Belongs to the 5'-nucleotidase family
AL541_10945	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AL541_10950	COG1187	pseudouridine synthase activity
AL541_10955	COG2840	Smr protein MutS2
AL541_10995	COG2217	Heavy metal translocating P-type atpase
AL541_10995	COG2608	mercury ion transmembrane transporter activity
AL541_11010	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
AL541_11065	COG0784	Response regulator, receiver
AL541_11065	COG0835	chemotaxis
AL541_11070	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AL541_11075	COG1815	bacterial-type flagellum-dependent cell motility
AL541_11080	COG1558	bacterial-type flagellum-dependent cell motility
AL541_11085	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
AL541_11090	COG1749	Flagellar hook protein flgE
AL541_11095	COG4787	bacterial-type flagellum-dependent cell motility
AL541_11100	COG4786	Flagellar basal body rod
AL541_11105	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
AL541_11110	COG1706	bacterial-type flagellum-dependent cell motility
AL541_11115	COG3951	Flagellar rod assembly protein muramidase FlgJ
AL541_11115	COG1705	Flagellar rod assembly protein muramidase FlgJ
AL541_11125	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AL541_11130	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AL541_11140	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AL541_11155	COG2190	(PTS) system
AL541_11160	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AL541_11165	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL541_11175	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AL541_11180	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
AL541_11185	COG3115	cell septum assembly
AL541_11190	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AL541_11215	COG0330	HflC and HflK could
AL541_11220	COG3118	belongs to the thioredoxin family
AL541_11230	COG0300	oxidoreductase activity
AL541_11235	COG1090	epimerase
AL541_11265	COG0622	Phosphoesterase
AL541_11285	COG3710	Transcriptional regulator
AL541_11290	COG0326	Molecular chaperone. Has ATPase activity
AL541_11300	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AL541_11305	COG3104	oligopeptide transport
AL541_11310	COG0250	Participates in transcription elongation, termination and antitermination
AL541_11315	COG0367	asparagine synthase
AL541_11320	COG4651	solute:proton antiporter activity
AL541_11320	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AL541_11325	COG1940	carbohydrate kinase activity
AL541_11325	COG1846	Transcriptional regulator
AL541_11330	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AL541_11340	COG2190	(PTS) system
AL541_11340	COG1263	PTS System
AL541_11340	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AL541_11345	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AL541_11350	COG0735	belongs to the Fur family
AL541_11360	COG0716	FMN binding
AL541_11370	COG0596	Alpha beta hydrolase
AL541_11375	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
AL541_11380	COG0033	Phosphoglucomutase
AL541_11390	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AL541_11400	COG2009	succinate dehydrogenase
AL541_11405	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
AL541_11410	COG1053	succinate dehydrogenase
AL541_11415	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AL541_11420	COG0567	Dehydrogenase, E1 component
AL541_11425	COG0508	dehydrogenase complex catalyzes the overall conversion of
AL541_11430	COG0045	succinate-CoA ligase (ADP-forming) activity
AL541_11440	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AL541_11445	COG1121	(ABC) transporter
AL541_11450	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
AL541_11455	COG4977	sequence-specific DNA binding
AL541_11460	COG1918	ferrous iron import across plasma membrane
AL541_11485	COG0018	arginyl-trna synthetase
AL541_11495	COG3102	Protein conserved in bacteria
AL541_11500	COG0788	formyltetrahydrofolate deformylase activity
AL541_11505	COG1199	ATP-dependent helicase activity
AL541_11510	COG1214	PFAM Peptidase M22, glycoprotease
AL541_11520	COG3065	identical protein binding
AL541_11525	COG2267	carboxylic ester hydrolase activity
AL541_11530	COG0318	PFAM AMP-dependent synthetase and ligase
AL541_11535	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
AL541_11545	COG2894	cell division
AL541_11550	COG0850	regulation of cytokinetic process
AL541_11555	COG3100	YcgL domain-containing protein
AL541_11560	COG2951	lytic endotransglycosylase activity
AL541_11570	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AL541_11575	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AL541_11590	COG1028	Short-chain dehydrogenase reductase Sdr
AL541_11595	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AL541_11600	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AL541_11625	COG2986	histidine ammonia-lyase
AL541_11630	COG1216	Glycosyl transferase, family 2
AL541_11635	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AL541_11650	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AL541_11655	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AL541_11690	COG0513	Belongs to the DEAD box helicase family
AL541_11695	COG0569	domain protein
AL541_11700	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AL541_11715	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
AL541_11720	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AL541_11725	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
AL541_11730	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AL541_11755	COG0544	peptidyl-prolyl cis-trans isomerase activity
AL541_11765	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AL541_11770	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AL541_11775	COG0776	regulation of translation
AL541_11780	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AL541_11785	COG1555	photosystem II stabilization
AL541_11800	COG0232	Belongs to the dGTPase family. Type 2 subfamily
AL541_11805	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
AL541_11810	COG0436	Aminotransferase
AL541_11815	COG1169	isochorismate synthase
AL541_11830	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
AL541_11835	COG1441	menaquinone biosynthetic process
AL541_11850	COG2855	membrane
AL541_11855	COG0477	Major facilitator Superfamily
AL541_11900	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL541_11905	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AL541_11920	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AL541_11925	COG1522	sequence-specific DNA binding
AL541_11935	COG1946	Acyl-CoA thioesterase
AL541_11940	COG3126	Type III secretion system lipoprotein chaperone (YscW)
AL541_11955	COG3706	GGDEF domain
AL541_11965	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AL541_11970	COG0516	GMP reductase activity
AL541_11970	COG0517	IMP dehydrogenase activity
AL541_11995	COG0537	adenosine 5'-monophosphoramidase activity
AL541_12020	COG3150	esterase
AL541_12025	COG1252	NADH dehydrogenase
AL541_12040	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AL541_12050	COG4591	ABC-type transport system involved in lipoprotein release permease component
AL541_12055	COG1136	(ABC) transporter
AL541_12060	COG4591	ABC-type transport system involved in lipoprotein release permease component
AL541_12070	COG0658	competence protein
AL541_12070	COG2333	competence protein COMEC
AL541_12080	COG1132	(ABC) transporter
AL541_12100	COG2719	SpoVR family
AL541_12105	COG2718	Belongs to the UPF0229 family
AL541_12110	COG2766	serine protein kinase
AL541_12120	COG3013	Belongs to the UPF0304 family
AL541_12130	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AL541_12140	COG1882	Formate acetyltransferase
AL541_12170	COG4215	(ABC) transporter
AL541_12185	COG0708	Exodeoxyribonuclease III
AL541_12195	COG3923	Primosomal replication protein n
AL541_12200	COG0730	response to heat
AL541_12205	COG1199	ATP-dependent helicase activity
AL541_12210	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AL541_12215	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
AL541_12220	COG1187	pseudouridine synthase activity
AL541_12230	COG1278	Cold shock
AL541_12235	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AL541_12240	COG0542	response to heat
AL541_12245	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AL541_12250	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
AL541_12255	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
AL541_12275	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AL541_12280	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AL541_12285	COG0297	glycogen (starch) synthase activity
AL541_12305	COG3070	regulator of competence-specific genes
AL541_12310	COG1609	Transcriptional regulator
AL541_12315	COG3381	protein complex oligomerization
AL541_12320	COG0745	RESPONSE REGULATOR receiver
AL541_12325	COG1434	Gram-negative-bacterium-type cell wall biogenesis
AL541_12330	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AL541_12335	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
AL541_12340	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
AL541_12345	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
AL541_12365	COG4067	protein conserved in archaea
AL541_12365	COG0189	ligase activity
AL541_12375	COG0500	methyltransferase
AL541_12385	COG1801	Protein of unknown function DUF72
AL541_12395	COG0217	transcriptional regulatory protein
AL541_12400	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
AL541_12405	COG0632	four-way junction helicase activity
AL541_12410	COG2255	four-way junction helicase activity
AL541_12415	COG1271	oxidase subunit
AL541_12420	COG1294	oxidase, subunit
AL541_12425	COG4890	Cyd operon protein YbgT
AL541_12435	COG0824	Thioesterase
AL541_12440	COG0811	peptide transport
AL541_12455	COG0823	Involved in the tonB-independent uptake of proteins
AL541_12460	COG2885	chlorophyll binding
AL541_12465	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
AL541_12470	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
AL541_12480	COG3766	membrane
AL541_12490	COG0754	glutathionylspermidine amidase activity
AL541_12500	COG0784	Response regulator, receiver
AL541_12500	COG5002	protein histidine kinase activity
AL541_12515	COG1294	oxidase, subunit
AL541_12520	COG1271	oxidase subunit
AL541_12540	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL541_12545	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AL541_12570	COG3568	Endonuclease Exonuclease Phosphatase
AL541_12595	COG0583	DNA-binding transcription factor activity
AL541_12605	COG0686	Belongs to the AlaDH PNT family
AL541_12615	COG1674	ftsk spoiiie
AL541_12625	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AL541_12645	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AL541_12670	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
AL541_12690	COG0300	oxidoreductase activity
AL541_12705	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AL541_12715	COG2268	Band 7 protein
AL541_12725	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AL541_12730	COG2915	High frequency lysogenization protein hflD homolog
AL541_12745	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AL541_12755	COG1757	Na H antiporter
AL541_12765	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AL541_12775	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AL541_12775	COG0131	Imidazoleglycerol-phosphate dehydratase
AL541_12780	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AL541_12785	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AL541_12790	COG0107	imidazoleglycerol-phosphate synthase activity
AL541_12795	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AL541_12795	COG0140	phosphoribosyl-ATP diphosphatase activity
AL541_12800	COG3012	SEC-C Motif Domain Protein
AL541_12805	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
AL541_12810	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AL541_12815	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AL541_12820	COG0215	cysteine-tRNA ligase activity
AL541_12825	COG1435	thymidine kinase activity
AL541_12830	COG1434	Gram-negative-bacterium-type cell wall biogenesis
AL541_12855	COG2116	formate transmembrane transporter activity
AL541_12865	COG0390	transport system, permease component
AL541_12870	COG4459	periplasmic nitrate reductase
AL541_12875	COG3005	denitrification pathway
AL541_12880	COG0243	molybdopterin cofactor binding
AL541_12895	COG1227	inorganic diphosphatase activity
AL541_12905	COG4172	Belongs to the ABC transporter superfamily
AL541_12915	COG4171	peptide transport system, permease
AL541_12920	COG4168	peptide transport system, permease
AL541_12930	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
AL541_12935	COG1842	Phage shock protein A
AL541_12945	COG1983	PspC domain protein
AL541_12965	COG2818	Glycosylase
AL541_12970	COG5380	lipid catabolic process
AL541_12975	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
AL541_12980	COG0626	cystathionine gamma-synthase activity
AL541_12990	COG0733	neurotransmitter:sodium symporter activity
AL541_12995	COG0564	pseudouridine synthase activity
AL541_13005	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AL541_13010	COG1151	hydroxylamine reductase activity
AL541_13015	COG3604	Transcriptional regulator
AL541_13030	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AL541_13035	COG4136	ATPase activity
AL541_13040	COG4135	transport system, permease component
AL541_13045	COG4134	Bacterial extracellular solute-binding protein
AL541_13055	COG3313	Fe-S protein
AL541_13080	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
AL541_13085	COG2205	protein histidine kinase activity
AL541_13100	COG1061	Type III restriction enzyme res subunit
AL541_13105	COG1187	pseudouridine synthase activity
AL541_13115	COG2814	Major facilitator Superfamily
AL541_13125	COG0702	epimerase
AL541_13130	COG0534	Mate efflux family protein
AL541_13150	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AL541_13165	COG1960	acyl-CoA dehydrogenase activity
AL541_13170	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AL541_13175	COG3273	potassium ion transport
AL541_13175	COG2985	domain, Protein
AL541_13180	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AL541_13190	COG1737	Transcriptional regulator
AL541_13195	COG0076	glutamate decarboxylase activity
AL541_13205	COG2431	L-lysine efflux transmembrane transporter activity
AL541_13225	COG3070	regulator of competence-specific genes
AL541_13240	COG4191	Histidine kinase
AL541_13240	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL541_13250	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
AL541_13260	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AL541_13265	COG4988	ABC transporter
AL541_13270	COG0492	ferredoxin-NADP+ reductase activity
AL541_13290	COG3706	GGDEF domain
AL541_13290	COG0745	RESPONSE REGULATOR receiver
AL541_13295	COG0471	metal ion transport
AL541_13300	COG2949	membrane
AL541_13305	COG0281	malic enzyme
AL541_13310	COG1643	Atp-dependent helicase
AL541_13320	COG1943	Transposase
AL541_13330	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AL541_13365	COG0247	lactate metabolic process
AL541_13365	COG0277	FAD linked oxidase domain protein
AL541_13380	COG2986	histidine ammonia-lyase
AL541_13385	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
AL541_13390	COG0010	Belongs to the arginase family
AL541_13395	COG1228	amidohydrolase
AL541_13415	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AL541_13425	COG0291	Belongs to the bacterial ribosomal protein bL35 family
AL541_13435	COG0393	Putative heavy-metal-binding
AL541_13470	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AL541_13475	COG0072	phenylalanine-tRNA ligase activity
AL541_13475	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AL541_13485	COG0776	regulation of translation
AL541_13495	COG0500	methyltransferase
AL541_13500	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
AL541_13505	COG0295	cytidine deaminase activity
AL541_13510	COG1346	cytolysis
AL541_13515	COG1380	Effector of murein hydrolase LrgA
AL541_13520	COG2925	Exonuclease
AL541_13530	COG0702	epimerase
AL541_13535	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
AL541_13540	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
AL541_13560	COG2988	succinylglutamate desuccinylase activity
AL541_13565	COG4139	cobalamin transport
AL541_13570	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
AL541_13590	COG0583	DNA-binding transcription factor activity
AL541_13600	COG1451	nucleotide metabolic process
AL541_13605	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
AL541_13635	COG3938	Belongs to the proline racemase family
AL541_13650	COG2423	ornithine cyclodeaminase activity
AL541_13655	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AL541_13660	COG3842	ATPase activity
AL541_13665	COG1176	ABC-type spermidine putrescine transport system, permease component I
AL541_13670	COG1177	transmembrane transport
AL541_13680	COG3291	Pkd domain containing protein
AL541_13700	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AL541_13705	COG0601	transmembrane transport
AL541_13715	COG2195	Cleaves the N-terminal amino acid of tripeptides
AL541_13725	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
AL541_13735	COG0625	glutathione transferase activity
AL541_13895	COG1742	UPF0060 membrane protein
AL541_13910	COG1757	Na H antiporter
AL541_13915	COG0174	glutamine synthetase
AL541_13925	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
AL541_13930	COG1917	Cupin 2, conserved barrel domain protein
AL541_13930	COG1396	sequence-specific DNA binding
AL541_13935	COG1012	belongs to the aldehyde dehydrogenase family
AL541_13940	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AL541_13950	COG2957	Belongs to the agmatine deiminase family
AL541_13955	COG1012	belongs to the aldehyde dehydrogenase family
AL541_13960	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AL541_13965	COG2200	EAL domain
AL541_13975	COG1846	Transcriptional regulator
AL541_13980	COG2315	Protein conserved in bacteria
AL541_14020	COG3063	Type IV pilus biogenesis stability protein PilW
AL541_14025	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
AL541_14040	COG1560	Kdo2-lipid A biosynthetic process
AL541_14045	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
AL541_14080	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AL541_14120	COG1160	GTP binding
AL541_14125	COG1160	GTP binding
AL541_14135	COG2916	Histone family protein nucleoid-structuring protein H-NS
AL541_14175	COG1479	Protein of unknown function DUF262
AL541_14215	COG2199	diguanylate cyclase activity
AL541_14260	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
AL541_14265	COG1280	lysine exporter protein (LysE YggA)
AL541_14275	COG1115	amino acid carrier protein
AL541_14300	COG1368	sulfuric ester hydrolase activity
AL541_14305	COG2113	Glycine betaine
AL541_14310	COG4176	ABC-type proline glycine betaine transport system permease component
AL541_14315	COG4175	Glycine betaine
AL541_14330	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AL541_14335	COG0456	acetyltransferase
AL541_14340	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AL541_14345	COG0662	Cupin 2, conserved barrel domain protein
AL541_14350	COG0527	aspartate kinase activity
AL541_14355	COG3119	arylsulfatase activity
AL541_14370	COG0641	radical SAM
AL541_14385	COG3119	arylsulfatase activity
AL541_14410	COG1538	Outer membrane efflux protein
AL541_14425	COG1349	DNA-binding transcription factor activity
AL541_14430	COG0673	inositol 2-dehydrogenase activity
AL541_14435	COG4702	Belongs to the UPF0303 family
AL541_14440	COG3706	GGDEF domain
AL541_14440	COG0745	RESPONSE REGULATOR receiver
AL541_14460	COG0471	metal ion transport
AL541_14475	COG5001	Diguanylate cyclase
AL541_14475	COG3300	MHYT domain
AL541_14490	COG1328	CTP reductase activity
AL541_14495	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AL541_14505	COG0861	Integral membrane protein TerC family
AL541_14515	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
AL541_14525	COG0814	amino acid
AL541_14540	COG1120	ATPase activity
AL541_14545	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AL541_14555	COG4774	siderophore transport
AL541_14565	COG1132	(ABC) transporter
AL541_14570	COG1132	(ABC) transporter
AL541_14585	COG0583	DNA-binding transcription factor activity
AL541_14610	COG0443	Heat shock 70 kDa protein
AL541_14615	COG0443	Heat shock 70 kDa protein
AL541_14660	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AL541_14665	COG1643	Atp-dependent helicase
AL541_14680	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AL541_14690	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AL541_14695	COG1215	transferase activity, transferring glycosyl groups
AL541_14700	COG0438	transferase activity, transferring glycosyl groups
AL541_14730	COG0438	transferase activity, transferring glycosyl groups
AL541_14740	COG2204	response regulator
AL541_14770	COG1793	dna ligase
AL541_14780	COG0534	Mate efflux family protein
AL541_14785	COG0307	riboflavin synthase, alpha
AL541_14805	COG3706	GGDEF domain
AL541_14815	COG0791	NLP P60 protein
AL541_14850	COG1940	carbohydrate kinase activity
AL541_14860	COG0303	'Molybdopterin
AL541_14865	COG0746	molybdenum cofactor guanylyltransferase activity
AL541_14870	COG3842	ATPase activity
AL541_14885	COG2204	response regulator
AL541_14890	COG4191	Histidine kinase
AL541_14900	COG0488	(ABC) transporter
AL541_14905	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AL541_14925	COG3381	protein complex oligomerization
AL541_14935	COG0243	molybdopterin cofactor binding
AL541_14935	COG3383	formate dehydrogenase (NAD+) activity
AL541_14940	COG0437	4 iron, 4 sulfur cluster binding
AL541_15090	COG0004	ammonium transporteR
AL541_15095	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AL541_15100	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AL541_15105	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AL541_15110	COG1177	transmembrane transport
AL541_15115	COG1176	ABC-type spermidine putrescine transport system, permease component I
AL541_15120	COG3842	ATPase activity
AL541_15145	COG0589	response to stress
AL541_15150	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AL541_15165	COG2217	Heavy metal translocating P-type atpase
AL541_15175	COG2010	Cytochrome c
AL541_15190	COG3278	Belongs to the heme-copper respiratory oxidase family
AL541_15205	COG2205	protein histidine kinase activity
AL541_15205	COG0784	Response regulator, receiver
AL541_15230	COG3120	sequence-specific DNA binding
AL541_15235	COG1067	ATP-dependent peptidase activity
AL541_15240	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AL541_15265	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AL541_15265	COG0116	Belongs to the methyltransferase superfamily
AL541_15275	COG0167	dihydroorotate dehydrogenase activity
AL541_15280	COG2902	Dehydrogenase
AL541_15290	COG0308	aminopeptidase N
AL541_15305	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
AL541_15310	COG1956	GAF domain-containing protein
AL541_15315	COG1132	(ABC) transporter
AL541_15320	COG2995	paraquat-inducible protein a
AL541_15325	COG3008	intermembrane lipid transfer
AL541_15350	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AL541_15355	COG1666	GTP binding
AL541_15370	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL541_15375	COG4597	amino acid ABC transporter
AL541_15380	COG0765	amino acid transport
AL541_15385	COG1126	abc transporter atp-binding protein
AL541_15390	COG0670	Belongs to the BI1 family
AL541_15400	COG2920	part of a sulfur-relay system
AL541_15405	COG1254	Belongs to the acylphosphatase family
AL541_15430	COG2885	chlorophyll binding
AL541_15465	COG2199	diguanylate cyclase activity
AL541_15465	COG2203	Gaf domain
AL541_15470	COG1414	Transcriptional regulator
AL541_15480	COG0656	L-ascorbic acid biosynthetic process
AL541_15485	COG0583	DNA-binding transcription factor activity
AL541_15495	COG0583	DNA-binding transcription factor activity
AL541_15500	COG2814	Major facilitator Superfamily
AL541_15520	COG1335	isochorismatase
AL541_15525	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL541_15540	COG0646	methionine synthase
AL541_15540	COG1410	methionine synthase
AL541_15545	COG1126	abc transporter atp-binding protein
AL541_15550	COG0765	amino acid transport
AL541_15555	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL541_15570	COG0583	DNA-binding transcription factor activity
AL541_15585	COG0583	DNA-binding transcription factor activity
AL541_15595	COG0583	DNA-binding transcription factor activity
AL541_15610	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
AL541_15615	COG0602	queuosine metabolic process
AL541_15620	COG0561	phosphatase activity
AL541_15645	COG2828	Protein conserved in bacteria
AL541_15655	COG0372	Belongs to the citrate synthase family
AL541_15660	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
AL541_15695	COG0730	response to heat
AL541_15720	COG0457	Tetratricopeptide repeat
AL541_15785	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AL541_15790	COG4790	Type iii secretion
AL541_15795	COG4794	Type iii secretion
AL541_15800	COG4791	protein targeting
AL541_15805	COG4792	protein secretion
AL541_15810	COG2207	Transcriptional regulator
AL541_15840	COG3177	Filamentation induced by cAMP protein fic
AL541_15860	COG4669	(LipO)protein
AL541_15930	COG1012	belongs to the aldehyde dehydrogenase family
AL541_15935	COG3284	Transcriptional regulator
AL541_15950	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
AL541_15955	COG0363	glucosamine-6-phosphate deaminase activity
AL541_15960	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AL541_15965	COG2207	Transcriptional regulator
AL541_15975	COG4565	transcriptional regulatory protein
AL541_15980	COG3290	protein histidine kinase activity
AL541_15995	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL541_16025	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
AL541_16035	COG2985	domain, Protein
AL541_16060	COG2272	Belongs to the type-B carboxylesterase lipase family
AL541_16065	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AL541_16070	COG0729	surface antigen
AL541_16080	COG1280	lysine exporter protein (LysE YggA)
AL541_16085	COG1280	lysine exporter protein (LysE YggA)
AL541_16090	COG5507	3-demethylubiquinone-9 3-methyltransferase
AL541_16110	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AL541_16115	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AL541_16120	COG0110	maltose O-acetyltransferase activity
AL541_16230	COG2824	Alkylphosphonate utilization operon protein PhnA
AL541_16325	COG2801	Transposase and inactivated derivatives
AL541_16715	COG1335	isochorismatase
AL541_16845	COG1280	lysine exporter protein (LysE YggA)
AL541_16915	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
AL541_17010	COG2852	Protein conserved in bacteria
AL541_17100	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
AL541_17185	COG0791	NLP P60 protein
AL541_17215	COG2026	Addiction module toxin, RelE StbE family
AL541_17275	COG2264	protein methyltransferase activity
AL541_17325	COG2977	Belongs to the P-Pant transferase superfamily
AL541_17335	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AL541_17340	COG1028	Short-chain dehydrogenase reductase Sdr
AL541_17345	COG1169	isochorismate synthase
AL541_17350	COG1021	2,3-dihydroxybenzoate-AMP ligase
AL541_17355	COG3433	isochorismatase activity
AL541_17355	COG1535	isochorismatase
AL541_17360	COG4592	Periplasmic binding protein
AL541_17370	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AL541_17375	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AL541_17380	COG1120	ATPase activity
AL541_17395	COG2382	esterase
AL541_17400	COG1629	transport
AL541_17400	COG4774	siderophore transport
AL541_17420	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AL541_17435	COG0653	protein targeting
AL541_17530	COG1335	isochorismatase
AL541_17765	COG0653	protein targeting
AL541_17920	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AL541_17930	COG3768	UPF0283 membrane protein
AL541_17935	COG3106	COG3106 Predicted ATPase
AL541_17955	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AL541_17960	COG2205	protein histidine kinase activity
AL541_17960	COG0784	Response regulator, receiver
AL541_17970	COG0494	nUDIX hydrolase
AL541_17975	COG0814	amino acid
AL541_17980	COG1760	l-serine dehydratase
AL541_17985	COG2200	EAL domain
AL541_17995	COG0720	synthase
AL541_18000	COG0840	transmembrane signaling receptor activity
AL541_18005	COG0017	Asparaginyl-tRNA synthetase
AL541_18015	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL541_18030	COG1448	Aminotransferase
AL541_18050	COG0840	transmembrane signaling receptor activity
AL541_18055	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AL541_18085	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
AL541_18100	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AL541_18105	COG3108	Peptidase M15
AL541_18110	COG2989	Protein conserved in bacteria
AL541_18135	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AL541_18145	COG3088	subunit of a heme lyase
AL541_18145	COG4235	cytochrome complex assembly
AL541_18155	COG1138	Cytochrome C-type biogenesis protein
AL541_18160	COG3301	Polysulphide reductase, NrfD
AL541_18165	COG0437	4 iron, 4 sulfur cluster binding
AL541_18175	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
AL541_18195	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AL541_18205	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AL541_18210	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AL541_18235	COG0019	diaminopimelate decarboxylase activity
AL541_18275	COG0322	excinuclease ABC activity
AL541_18280	COG2197	response regulator
AL541_18285	COG0417	DNA replication proofreading
AL541_18305	COG1187	pseudouridine synthase activity
AL541_18315	COG0009	L-threonylcarbamoyladenylate synthase
AL541_18320	COG0613	PHP domain protein
AL541_18330	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AL541_18335	COG0512	Glutamine amidotransferase of anthranilate synthase
AL541_18345	COG0135	phosphoribosylanthranilate isomerase activity
AL541_18345	COG0134	indole-3-glycerol-phosphate synthase activity
AL541_18355	COG0159	tryptophan synthase activity
AL541_18360	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AL541_18365	COG0318	PFAM AMP-dependent synthetase and ligase
AL541_18375	COG1301	dicarboxylic acid transport
AL541_18395	COG2917	probably involved in intracellular septation
AL541_18400	COG1607	acyl-coa hydrolase
AL541_18405	COG2350	Protein conserved in bacteria
AL541_18415	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AL541_18420	COG0583	DNA-binding transcription factor activity
AL541_18435	COG5001	Diguanylate cyclase
AL541_18440	COG1032	radical SAM domain protein
AL541_18460	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AL541_18465	COG0463	Glycosyl transferase, family 2
AL541_18470	COG0745	RESPONSE REGULATOR receiver
AL541_18475	COG5002	protein histidine kinase activity
AL541_18475	COG3850	Histidine kinase
AL541_18510	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AL541_18530	COG1136	(ABC) transporter
AL541_18530	COG0577	efflux transmembrane transporter activity
AL541_18540	COG0577	efflux transmembrane transporter activity
AL541_18540	COG1136	(ABC) transporter
AL541_18550	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL541_18570	COG3118	belongs to the thioredoxin family
AL541_18575	COG4232	protein-disulfide reductase activity
AL541_18610	COG2863	cytochrome
AL541_18615	COG3258	Cytochrome c
AL541_18620	COG2995	paraquat-inducible protein a
AL541_18625	COG3008	intermembrane lipid transfer
AL541_18625	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AL541_18645	COG4166	transmembrane transport
AL541_18655	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
AL541_18660	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
AL541_18670	COG0539	negative regulation of cytoplasmic translation
AL541_18675	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AL541_18680	COG0616	signal peptide processing
AL541_18685	COG1028	Short-chain dehydrogenase reductase Sdr
AL541_18700	COG0587	DNA-directed DNA polymerase activity
AL541_18705	COG0784	Response regulator, receiver
AL541_18705	COG0835	chemotaxis
AL541_18710	COG1940	carbohydrate kinase activity
AL541_18715	COG0469	pyruvate kinase activity
AL541_18720	COG4667	esterase of the alpha-beta hydrolase superfamily
AL541_18735	COG0733	neurotransmitter:sodium symporter activity
AL541_18745	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AL541_18745	COG1263	PTS System
AL541_18750	COG0084	hydrolase, TatD family'
AL541_18755	COG0470	DNA polymerase III
AL541_18760	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AL541_18765	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AL541_18795	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AL541_18800	COG0416	fatty acid biosynthetic process
AL541_18810	COG1399	metal-binding, possibly nucleic acid-binding protein
AL541_18815	COG0424	maF-like protein
AL541_18820	COG0564	pseudouridine synthase activity
AL541_18830	COG1530	ribonuclease E activity
AL541_18840	COG0659	secondary active sulfate transmembrane transporter activity
AL541_18845	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AL541_18850	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
AL541_18860	COG0572	uridine kinase
AL541_18870	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AL541_18870	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AL541_18890	COG2186	Transcriptional regulator
AL541_18895	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AL541_18900	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
AL541_18905	COG0653	protein targeting
AL541_18910	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AL541_18915	COG3706	GGDEF domain
AL541_18920	COG0366	Alpha amylase catalytic
AL541_18925	COG1122	ATPase activity
AL541_18930	COG4120	Belongs to the binding-protein-dependent transport system permease family
AL541_18940	COG3092	negative regulation of chromosome organization
AL541_18945	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AL541_18950	COG0857	belongs to the CobB CobQ family
AL541_18950	COG0280	phosphate acetyltransferase
AL541_18960	COG0435	Glutathione S-transferase
AL541_18970	COG0444	Belongs to the ABC transporter superfamily
AL541_18975	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AL541_18980	COG0601	transmembrane transport
AL541_18990	COG0314	molybdopterin synthase activity
AL541_18995	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
AL541_19000	COG0315	cyclic pyranopterin monophosphate synthase activity
AL541_19005	COG0521	Mo-molybdopterin cofactor biosynthetic process
AL541_19010	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AL541_19015	COG0391	Required for morphogenesis under gluconeogenic growth conditions
AL541_19020	COG2198	Histidine kinase
AL541_19025	COG2204	response regulator
AL541_19030	COG0556	nucleotide-excision repair
AL541_19040	COG1882	Formate acetyltransferase
AL541_19045	COG4657	Part of a membrane complex involved in electron transport
AL541_19050	COG2878	Part of a membrane complex involved in electron transport
AL541_19055	COG4656	Part of a membrane complex involved in electron transport
AL541_19060	COG4658	electron transport chain
AL541_19065	COG4659	FMN binding
AL541_19070	COG4660	Part of a membrane complex involved in electron transport
AL541_19075	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AL541_19080	COG0346	lactoylglutathione lyase activity
AL541_19090	COG2885	chlorophyll binding
AL541_19100	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AL541_19105	COG2056	Na+-H+ antiporter family
AL541_19125	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AL541_19150	COG1454	alcohol dehydrogenase
AL541_19150	COG1012	belongs to the aldehyde dehydrogenase family
AL541_19155	COG2095	MarC family integral membrane protein
AL541_19160	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AL541_19165	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AL541_19170	COG1757	Na H antiporter
AL541_19185	COG3081	Nucleoid-associated protein
AL541_19190	COG3082	Protein of unknown function (DUF1414)
AL541_19205	COG0123	including yeast histone deacetylase and acetoin utilization protein
AL541_19220	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AL541_19225	COG0778	Nitroreductase
AL541_19235	COG0446	pyridine nucleotide-disulphide oxidoreductase
AL541_19235	COG1902	pentaerythritol trinitrate reductase activity
AL541_19240	COG0616	signal peptide processing
AL541_19245	COG0252	asparaginase activity
AL541_19250	COG3139	Protein of unknown function (DUF1315)
AL541_19260	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AL541_19265	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AL541_19270	COG0676	glucose-6-phosphate 1-epimerase activity
AL541_19280	COG2226	methyltransferase
AL541_19300	COG1785	Belongs to the alkaline phosphatase family
AL541_19310	COG0346	lactoylglutathione lyase activity
AL541_19315	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
AL541_19320	COG0668	transmembrane transport
AL541_19325	COG2983	Belongs to the UPF0260 family
AL541_19330	COG2261	transglycosylase associated protein
AL541_19340	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AL541_19345	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AL541_19350	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
AL541_19360	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AL541_19365	COG2832	Protein of unknown function (DUF454)
AL541_19375	COG0745	RESPONSE REGULATOR receiver
AL541_19380	COG0583	DNA-binding transcription factor activity
AL541_19385	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AL541_19390	COG1286	toxin biosynthetic process
AL541_19395	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
AL541_19400	COG0285	dihydrofolate synthase activity
AL541_19405	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AL541_19415	COG0101	tRNA pseudouridine synthase activity
AL541_19425	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AL541_19430	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AL541_19440	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AL541_19445	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
AL541_19445	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AL541_19450	COG0431	NADPH-dependent FMN reductase
AL541_19465	COG3101	peptidyl-lysine hydroxylation
AL541_19475	COG2860	membrane
AL541_19480	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AL541_19485	COG2890	protein-(glutamine-N5) methyltransferase activity
AL541_19490	COG2840	Smr protein MutS2
AL541_19495	COG2062	phosphohistidine phosphatase, SixA
AL541_19510	COG1024	Enoyl-CoA hydratase
AL541_19510	COG1250	3-hydroxyacyl-CoA dehydrogenase
AL541_19515	COG0183	Belongs to the thiolase family
AL541_19540	COG2067	long-chain fatty acid transport protein
AL541_19550	COG3088	subunit of a heme lyase
AL541_19550	COG4235	cytochrome complex assembly
AL541_19560	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AL541_19565	COG1138	Cytochrome C-type biogenesis protein
AL541_19570	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
AL541_19575	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AL541_19580	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AL541_19585	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AL541_19590	COG4133	protoheme IX ABC transporter activity
AL541_19600	COG0835	chemotaxis
AL541_19610	COG1192	Involved in chromosome partitioning
AL541_19615	COG2201	protein-glutamate methylesterase activity
AL541_19620	COG0643	Histidine kinase
AL541_19620	COG2198	Histidine kinase
AL541_19625	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
AL541_19640	COG0455	bacterial-type flagellum organization
AL541_19660	COG1684	flagellar biosynthetic protein fliR
AL541_19665	COG1987	bacterial-type flagellum assembly
AL541_19720	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AL541_19730	COG1677	Flagellar hook-basal body complex protein FliE
AL541_19735	COG2204	response regulator
AL541_19740	COG4191	Histidine kinase
AL541_19745	COG2204	response regulator
AL541_19750	COG1516	flagellar protein fliS
AL541_19760	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
AL541_19765	COG1334	flagellar protein FlaG
AL541_19770	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AL541_19775	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AL541_19785	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AL541_19790	COG2837	iron assimilation
AL541_19815	COG1393	Belongs to the ArsC family
AL541_19820	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AL541_19840	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AL541_19850	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AL541_19865	COG4783	chaperone-mediated protein folding
AL541_19870	COG1393	Belongs to the ArsC family
AL541_19890	COG2233	PERMEase
AL541_19895	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AL541_19900	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AL541_19905	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AL541_19910	COG0121	glutamine amidotransferase
AL541_19915	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
AL541_19920	COG1960	acyl-CoA dehydrogenase activity
AL541_19950	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AL541_19955	COG0328	RNA-DNA hybrid ribonuclease activity
AL541_19960	COG2226	methyltransferase
AL541_19965	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AL541_19970	COG1388	LysM domain
AL541_19970	COG0741	lytic transglycosylase activity
AL541_19980	COG3021	interspecies interaction between organisms
AL541_19985	COG0347	Belongs to the P(II) protein family
AL541_20000	COG0825	malonyl-CoA metabolic process
AL541_20005	COG0587	DNA-directed DNA polymerase activity
AL541_20015	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AL541_20020	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AL541_20030	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AL541_20035	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
AL541_20045	COG0750	zinc metalloprotease
AL541_20050	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AL541_20055	COG0575	Belongs to the CDS family
AL541_20060	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AL541_20065	COG0233	cytoplasmic translational termination
AL541_20070	COG0528	UMP kinase activity
AL541_20075	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AL541_20080	COG0052	Belongs to the universal ribosomal protein uS2 family
AL541_20085	COG0024	Methionine aminopeptidase
AL541_20090	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
AL541_20100	COG0564	pseudouridine synthase activity
AL541_20105	COG3098	single-species biofilm formation
AL541_20140	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AL541_20145	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AL541_20170	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
AL541_20180	COG0254	rRNA binding
AL541_20185	COG1720	tRNA m6t6A37 methyltransferase activity
AL541_20190	COG0442	prolyl-tRNA aminoacylation
AL541_20210	COG0733	neurotransmitter:sodium symporter activity
AL541_20225	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AL541_20230	COG0514	ATP-dependent DNA helicase (RecQ)
AL541_20235	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AL541_20245	COG0745	RESPONSE REGULATOR receiver
AL541_20245	COG3706	GGDEF domain
AL541_20255	COG1477	protein flavinylation
AL541_20260	COG2871	sodium ion transport
AL541_20265	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AL541_20270	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AL541_20275	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AL541_20280	COG1805	sodium ion transport
AL541_20285	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AL541_20295	COG0271	Belongs to the BolA IbaG family
AL541_20300	COG2813	Specifically methylates the guanine in position
AL541_20305	COG3056	Lipoprotein
AL541_20325	COG1595	DNA-templated transcription, initiation
AL541_20350	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AL541_20355	COG0693	protein deglycase activity
AL541_20360	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AL541_20365	COG3706	GGDEF domain
AL541_20370	COG2166	iron-sulfur cluster assembly
AL541_20375	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AL541_20380	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
AL541_20395	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
AL541_20395	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AL541_20415	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AL541_20420	COG1074	ATP-dependent DNA helicase activity
AL541_20430	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
AL541_20450	COG3141	response to X-ray
AL541_20465	COG2171	N-acyltransferase activity
AL541_20470	COG0584	glycerophosphoryl diester phosphodiesterase
AL541_20475	COG2271	Major facilitator Superfamily
AL541_20485	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AL541_20490	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AL541_20495	COG1349	DNA-binding transcription factor activity
AL541_20500	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AL541_20505	COG0598	Magnesium transport protein CorA
AL541_20525	COG1609	Transcriptional regulator
AL541_20530	COG0583	DNA-binding transcription factor activity
AL541_20570	COG1022	Amp-dependent synthetase and ligase
AL541_20580	COG0583	DNA-binding transcription factor activity
AL541_20585	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AL541_20590	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
AL541_20600	COG0560	Phosphoserine phosphatase
AL541_20610	COG0813	purine-nucleoside phosphorylase activity
AL541_20615	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
AL541_20620	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
AL541_20625	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
AL541_20630	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AL541_20635	COG0084	hydrolase, TatD family'
AL541_20665	COG3153	acetyltransferase
AL541_20695	COG0534	Mate efflux family protein
AL541_20710	COG1185	polyribonucleotide nucleotidyltransferase activity
AL541_20715	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AL541_20720	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AL541_20725	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AL541_20730	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AL541_20735	COG0195	Participates in both transcription termination and antitermination
AL541_20740	COG0779	Required for maturation of 30S ribosomal subunits
AL541_20755	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AL541_20765	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AL541_20770	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AL541_20775	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AL541_20780	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
AL541_20785	COG1534	Rna-binding protein
AL541_20790	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AL541_20795	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AL541_20800	COG2027	D-alanyl-D-alanine carboxypeptidase
AL541_20810	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AL541_20815	COG0739	heme binding
AL541_20840	COG0628	permease
AL541_20855	COG0747	negative chemotaxis
AL541_20865	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AL541_20870	COG0444	Belongs to the ABC transporter superfamily
AL541_20875	COG4608	Belongs to the ABC transporter superfamily
AL541_20885	COG2971	BadF BadG BcrA BcrD
AL541_20900	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AL541_20905	COG3842	ATPase activity
AL541_20915	COG1840	ABC-type Fe3 transport system, periplasmic component
AL541_20920	COG0004	ammonium transporteR
AL541_20930	COG3112	Uncharacterised protein family (UPF0231)
AL541_20935	COG1049	propionate catabolic process, 2-methylcitrate cycle
AL541_20940	COG1752	Esterase of the alpha-beta hydrolase superfamily
AL541_20945	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AL541_20950	COG1643	Atp-dependent helicase
AL541_20955	COG1489	DNA binding
AL541_20960	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AL541_20965	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AL541_20975	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AL541_20980	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
AL541_20985	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
AL541_20990	COG1560	Kdo2-lipid A biosynthetic process
AL541_21000	COG0842	Transport permease protein
AL541_21005	COG1131	(ABC) transporter
AL541_21010	COG0659	secondary active sulfate transmembrane transporter activity
AL541_21015	COG0288	reversible hydration of carbon dioxide
AL541_21030	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AL541_21035	COG0508	dehydrogenase complex catalyzes the overall conversion of
AL541_21040	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
AL541_21045	COG2186	Transcriptional regulator
AL541_21055	COG0157	Belongs to the NadC ModD family
AL541_21065	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AL541_21070	COG1459	type II secretion system
AL541_21080	COG0237	dephospho-CoA kinase activity
AL541_21085	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
AL541_21090	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
AL541_21105	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AL541_21110	COG0228	four-way junction DNA binding
AL541_21115	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AL541_21120	COG4137	Cytochrome C assembly protein
AL541_21125	COG4536	flavin adenine dinucleotide binding
AL541_21130	COG1854	S-ribosylhomocysteine lyase activity
AL541_21145	COG0612	Peptidase, M16
AL541_21150	COG1238	metal cluster binding
AL541_21160	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
AL541_21165	COG0511	ligase activity, forming carbon-carbon bonds
AL541_21165	COG5016	pyruvate
AL541_21230	COG0527	aspartate kinase activity
AL541_21235	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AL541_21240	COG2137	regulation of response to DNA damage stimulus
AL541_21245	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AL541_21250	COG1546	Belongs to the CinA family
AL541_21255	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AL541_21260	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AL541_21270	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AL541_21275	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
AL541_21285	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
AL541_21290	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
AL541_21295	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
AL541_21300	COG0148	phosphopyruvate hydratase activity
AL541_21305	COG0504	CTP synthase activity
AL541_21310	COG3956	TIGRFAM MazG family protein
AL541_21315	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AL541_21325	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AL541_21340	COG0736	holo-[acyl-carrier-protein] synthase activity
AL541_21345	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AL541_21350	COG1381	Involved in DNA repair and RecF pathway recombination
AL541_21355	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AL541_21365	COG0681	Belongs to the peptidase S26 family
AL541_21370	COG0481	GTPase activity
AL541_21375	COG3086	response to oxidative stress
AL541_21390	COG1595	DNA-templated transcription, initiation
AL541_21400	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AL541_21410	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
AL541_21415	COG0354	folic acid binding
AL541_21430	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AL541_21435	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AL541_21440	COG3079	Belongs to the UPF0149 family
AL541_21450	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
AL541_21460	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AL541_21465	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
AL541_21470	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AL541_21480	COG0583	DNA-binding transcription factor activity
AL541_21495	COG0668	transmembrane transport
AL541_21500	COG0191	fructose-bisphosphate aldolase activity
AL541_21515	COG4771	TonB-dependent receptor
AL541_21520	COG0583	DNA-binding transcription factor activity
AL541_21525	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AL541_21535	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AL541_21550	COG2356	endonuclease I
AL541_21555	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AL541_21560	COG0189	ligase activity
AL541_21565	COG1678	Uncharacterized ACR, COG1678
AL541_21570	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AL541_21585	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AL541_21590	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AL541_21595	COG0762	integral membrane protein
AL541_21600	COG1872	DUF167
AL541_21610	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AL541_21615	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AL541_21620	COG2066	Belongs to the glutaminase family
AL541_21630	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AL541_21640	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
AL541_21685	COG0840	transmembrane signaling receptor activity
AL541_21765	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
AL541_21775	COG3394	polysaccharide catabolic process
AL541_21780	COG1486	melibiose metabolic process
AL541_21785	COG1447	Phosphotransferase system cellobiose-specific component IIA
AL541_21790	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AL541_21800	COG0726	polysaccharide deacetylase
AL541_21895	COG1028	Short-chain dehydrogenase reductase Sdr
AL541_21900	COG4325	translation initiation factor activity
AL541_21910	COG0795	lipopolysaccharide-transporting ATPase activity
AL541_21915	COG0795	lipopolysaccharide-transporting ATPase activity
AL541_21920	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AL541_21925	COG2927	DNA polymerase III (CHI subunit)
AL541_21930	COG0525	valine-tRNA ligase activity
AL541_21940	COG0456	acetyltransferase
AL541_21970	COG0540	Belongs to the ATCase OTCase family
AL541_21975	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
AL541_21980	COG0251	oxidation-reduction process
AL541_21985	COG0204	Acyl-transferase
AL541_21990	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AL541_21995	COG5007	Belongs to the BolA IbaG family
AL541_22005	COG2854	intermembrane phospholipid transfer
AL541_22010	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AL541_22015	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AL541_22020	COG1127	ABC transporter
AL541_22030	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AL541_22030	COG0517	IMP dehydrogenase activity
AL541_22040	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
AL541_22045	COG1137	ATPase activity
AL541_22055	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AL541_22060	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL541_22065	COG1660	Displays ATPase and GTPase activities
AL541_22070	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL541_22075	COG2239	Acts as a magnesium transporter
AL541_22080	COG0312	modulator of DNA gyrase
AL541_22085	COG3028	Belongs to the UPF0307 family
AL541_22090	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AL541_22095	COG0564	pseudouridine synthase activity
AL541_22105	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AL541_22110	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
AL541_22115	COG0312	modulator of DNA gyrase
AL541_22120	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AL541_22125	COG3164	Protein of unknown function
AL541_22130	COG1530	ribonuclease E activity
AL541_22135	COG0424	maF-like protein
AL541_22140	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
AL541_22145	COG1792	Involved in formation and maintenance of cell shape
AL541_22150	COG1077	Cell shape determining protein MreB Mrl
AL541_22185	COG4969	Belongs to the N-Me-Phe pilin family
AL541_22195	COG1459	type II secretion system
AL541_22200	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AL541_22210	COG3409	Peptidoglycan-binding domain 1 protein
AL541_22210	COG3267	Type II secretory pathway component ExeA
AL541_22215	COG1450	Type ii and iii secretion system protein
AL541_22235	COG2199	diguanylate cyclase activity
AL541_22235	COG2200	EAL domain
AL541_22240	COG0629	single-stranded DNA binding
AL541_22255	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AL541_22265	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AL541_22275	COG0527	aspartate kinase activity
AL541_22280	COG1410	methionine synthase
AL541_22280	COG0646	methionine synthase
AL541_22345	COG0175	sulfate reduction
AL541_22350	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AL541_22355	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AL541_22375	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AL541_22380	COG0735	belongs to the Fur family
AL541_22390	COG0166	Belongs to the GPI family
AL541_22395	COG0432	Pfam Uncharacterised protein family UPF0047
AL541_22400	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AL541_22405	COG0305	Participates in initiation and elongation during chromosome replication
AL541_22425	COG2965	DNA replication, synthesis of RNA primer
AL541_22430	COG0360	Binds together with S18 to 16S ribosomal RNA
AL541_22435	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AL541_22440	COG0338	D12 class N6 adenine-specific DNA methyltransferase
AL541_22450	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AL541_22455	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AL541_22485	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AL541_22495	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AL541_22495	COG0678	peroxiredoxin activity
AL541_22500	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AL541_22510	COG0165	Argininosuccinate lyase
AL541_22510	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
AL541_22515	COG0137	argininosuccinate synthase activity
AL541_22525	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AL541_22535	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
AL541_22545	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AL541_22550	COG0460	homoserine dehydrogenase
AL541_22550	COG0527	aspartate kinase activity
AL541_22555	COG0626	cystathionine gamma-synthase activity
AL541_22565	COG0281	malic enzyme
AL541_22575	COG2906	2 iron, 2 sulfur cluster binding
AL541_22580	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AL541_22585	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AL541_22605	COG2923	Belongs to the DsrF TusC family
AL541_22610	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
AL541_22615	COG2964	Protein conserved in bacteria
AL541_22620	COG0545	Peptidyl-prolyl cis-trans isomerase
AL541_22635	COG1446	asparaginase
AL541_22645	COG1047	Peptidyl-prolyl cis-trans
AL541_22660	COG2249	NAD(P)H dehydrogenase (quinone) activity
AL541_22665	COG0488	(ABC) transporter
AL541_22675	COG0429	hydrolase of the alpha beta-hydrolase fold
AL541_22685	COG3954	Phosphoribulokinase
AL541_22690	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AL541_22710	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AL541_22715	COG0512	Glutamine amidotransferase of anthranilate synthase
AL541_22730	COG0180	Tryptophanyl-tRNA synthetase
AL541_22735	COG0546	phosphoglycolate phosphatase activity
AL541_22740	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AL541_22745	COG0557	exoribonuclease II activity
AL541_22750	COG1959	2 iron, 2 sulfur cluster binding
AL541_22755	COG1017	nitric oxide dioxygenase activity
AL541_22755	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AL541_22760	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
AL541_22770	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AL541_22775	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
AL541_22780	COG0330	HflC and HflK could
AL541_22785	COG0330	HflC and HflK could
AL541_22790	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AL541_22800	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AL541_22805	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AL541_22815	COG0802	atpase or kinase
AL541_22825	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AL541_22890	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
AL541_22895	COG1162	GTPase activity
AL541_22900	COG0688	phosphatidylethanolamine metabolic process
AL541_22905	COG0471	metal ion transport
AL541_22915	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
AL541_22920	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AL541_22925	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
AL541_22930	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AL541_22935	COG1045	serine acetyltransferase
AL541_22940	COG4942	peptidase
AL541_22960	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
AL541_22965	COG1053	succinate dehydrogenase
AL541_22970	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AL541_22975	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
AL541_22980	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
AL541_22995	COG1509	lysine 2,3-aminomutase activity
AL541_23000	COG1285	pathogenesis
AL541_23010	COG0459	protein refolding
AL541_23015	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AL541_23020	COG0534	Mate efflux family protein
AL541_23025	COG0205	6-phosphofructokinase activity
AL541_23035	COG3678	ATP-independent chaperone mediated protein folding
AL541_23040	COG0745	RESPONSE REGULATOR receiver
AL541_23045	COG2205	protein histidine kinase activity
AL541_23055	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AL541_23060	COG3030	protein affecting phage T7 exclusion by the F plasmid
AL541_23065	COG1027	Aspartate ammonia-lyase
AL541_23070	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
AL541_23075	COG4232	protein-disulfide reductase activity
AL541_23085	COG3263	regulation of cellular component size
AL541_23095	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AL541_23120	COG2814	Major facilitator Superfamily
AL541_23135	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AL541_23140	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AL541_23145	COG0511	ligase activity, forming carbon-carbon bonds
AL541_23150	COG0439	Biotin carboxylase
AL541_23160	COG2264	protein methyltransferase activity
AL541_23165	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AL541_23170	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
AL541_23180	COG0488	(ABC) transporter
AL541_23235	COG1982	Orn Lys Arg decarboxylase major
AL541_23240	COG0531	amino acid
AL541_23250	COG3710	Transcriptional regulator
AL541_23255	COG0789	Transcriptional regulator
AL541_23270	COG0151	Belongs to the GarS family
AL541_23285	COG1253	flavin adenine dinucleotide binding
AL541_23290	COG3068	Protein conserved in bacteria
AL541_23300	COG1573	uracil-dna glycosylase
AL541_23305	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
AL541_23310	COG2816	NAD+ diphosphatase activity
AL541_23315	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
AL541_23320	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AL541_23325	COG0085	RNA polymerase activity
AL541_23330	COG0222	ribosome binding
AL541_23335	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AL541_23350	COG0250	Participates in transcription elongation, termination and antitermination
AL541_23355	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AL541_23365	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AL541_23400	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
AL541_23400	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
AL541_23405	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AL541_23415	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AL541_23490	COG4206	TonB-dependent receptor
AL541_23510	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AL541_23515	COG0534	Mate efflux family protein
AL541_23520	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
AL541_23530	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AL541_23540	COG2937	Belongs to the GPAT DAPAT family
AL541_23545	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AL541_23550	COG3161	chorismate lyase activity
AL541_23555	COG1580	Controls the rotational direction of flagella during chemotaxis
AL541_23560	COG0705	Rhomboid family
AL541_23565	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AL541_23580	COG2177	Part of the ABC transporter FtsEX involved in
AL541_23585	COG2884	Cell division ATP-binding protein ftsE
AL541_23590	COG0552	protein localization to endoplasmic reticulum
AL541_23595	COG0742	ribosomal rna small subunit methyltransferase
AL541_23605	COG2095	MarC family integral membrane protein
AL541_23650	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AL541_23655	COG0640	Transcriptional regulator
AL541_23660	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
AL541_23665	COG1280	lysine exporter protein (LysE YggA)
AL541_23670	COG2267	carboxylic ester hydrolase activity
AL541_23675	COG0561	phosphatase activity
AL541_23695	COG3287	FIST C domain
AL541_23695	COG2200	EAL domain
AL541_23695	COG2199	diguanylate cyclase activity
AL541_23700	COG1011	Hydrolase
AL541_23705	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
AL541_23720	COG0019	diaminopimelate decarboxylase activity
AL541_23730	COG1965	Belongs to the frataxin family
AL541_23735	COG3072	Adenylate cyclase
AL541_23740	COG0181	hydroxymethylbilane synthase activity
AL541_23745	COG1587	Uroporphyrinogen-III synthase
AL541_23750	COG2959	enzyme of heme biosynthesis
AL541_23755	COG3071	HemY protein
AL541_23800	COG0633	Ferredoxin
AL541_23805	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
AL541_23815	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AL541_23820	COG3118	belongs to the thioredoxin family
AL541_23825	COG0513	Belongs to the DEAD box helicase family
AL541_23830	COG0248	Ppx GppA phosphatase
AL541_23840	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
AL541_23855	COG0514	ATP-dependent DNA helicase (RecQ)
AL541_23860	COG2962	Rard protein
AL541_23870	COG1280	lysine exporter protein (LysE YggA)
AL541_23875	COG0405	Gamma-glutamyltransferase
AL541_23885	COG0210	DNA helicase
AL541_23895	COG3220	belongs to the UPF0276 family
AL541_23925	COG0006	proline dipeptidase activity
AL541_23925	COG0006	proline dipeptidase activity
AL541_23945	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AL541_23965	COG2132	Multicopper oxidase
AL541_24010	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AL541_24030	COG0009	L-threonylcarbamoyladenylate synthase
AL541_24035	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AL541_24040	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AL541_24045	COG0551	DNA topoisomerase type I activity
AL541_24055	COG2922	Belongs to the Smg family
AL541_24060	COG0758	DNA mediated transformation
AL541_24070	COG0242	peptide deformylase activity
AL541_24075	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AL541_24080	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AL541_24080	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AL541_24085	COG0569	domain protein
AL541_24090	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AL541_24100	COG1272	protein, Hemolysin III
AL541_24105	COG4326	sporulation control protein
AL541_24115	COG3084	Protein conserved in bacteria
AL541_24125	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AL541_24130	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AL541_24135	COG0204	Acyl-transferase
AL541_24145	COG0606	chelatase, subunit chli
AL541_24155	COG3978	acetolactate synthase activity
AL541_24160	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AL541_24165	COG0129	dihydroxy-acid dehydratase activity
AL541_24175	COG0583	DNA-binding transcription factor activity
AL541_24180	COG2814	Major facilitator Superfamily
AL541_24185	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL541_24190	COG0765	amino acid transport
AL541_24200	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AL541_24205	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AL541_24210	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AL541_24215	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AL541_24220	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AL541_24225	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AL541_24235	COG0356	it plays a direct role in the translocation of protons across the membrane
AL541_24240	COG3312	ion transport
AL541_24245	COG1475	DNA binding
AL541_24250	COG1192	Involved in chromosome partitioning
AL541_24255	COG0357	Ribosomal RNA small subunit methyltransferase G
AL541_24260	COG0445	tRNA wobble uridine modification
AL541_24265	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AL541_24275	COG0706	membrane insertase activity
AL541_24280	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
AL541_24285	COG0594	ribonuclease P activity
AL541_24295	COG1126	abc transporter atp-binding protein
AL541_24315	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AL541_24320	COG0592	DNA-directed DNA polymerase activity
AL541_24330	COG0187	DNA topoisomerase II activity
AL541_24350	COG0071	Belongs to the small heat shock protein (HSP20) family
AL541_24355	COG3977	Valine--pyruvate aminotransferase
AL541_24360	COG0366	Alpha amylase catalytic
AL541_24375	COG2119	membrane
AL541_24385	COG0425	Belongs to the sulfur carrier protein TusA family
AL541_24400	COG0604	alcohol dehydrogenase
AL541_24405	COG0183	Belongs to the thiolase family
AL541_24415	COG1739	Uncharacterized protein family UPF0029
AL541_24420	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AL541_24465	COG0583	DNA-binding transcription factor activity
AL541_24470	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AL541_24475	COG2960	long-chain fatty acid transporting porin activity
AL541_24480	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AL541_24485	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL541_24540	COG4172	Belongs to the ABC transporter superfamily
AL541_24545	COG4166	transmembrane transport
AL541_24555	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AL541_24595	COG1609	Transcriptional regulator
AL541_24600	COG0583	DNA-binding transcription factor activity
AL541_24610	COG2076	Multidrug Resistance protein
AL541_24615	COG0129	dihydroxy-acid dehydratase activity
AL541_24620	COG3265	gluconokinase activity
AL541_24625	COG2610	gluconate transmembrane transporter activity
AL541_24630	COG0800	Aldolase
AL541_24635	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
AL541_24640	COG0583	DNA-binding transcription factor activity
AL541_24645	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AL541_24650	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
AL541_24660	COG1522	sequence-specific DNA binding
AL541_24665	COG5001	Diguanylate cyclase
AL541_24665	COG5002	protein histidine kinase activity
AL541_24680	COG0697	spore germination
AL541_24685	COG0589	response to stress
AL541_24690	COG1528	Iron-storage protein
AL541_24700	COG2081	HI0933 family
AL541_24730	COG1597	lipid kinase activity
AL541_24760	COG0628	permease
AL541_24775	COG1322	Protein conserved in bacteria
AL541_24780	COG2226	methyltransferase
AL541_24785	COG3165	ubiquinone biosynthetic process from chorismate
AL541_24790	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AL541_24805	COG0805	protein transport
AL541_24815	COG0084	hydrolase, TatD family'
AL541_24830	COG0456	acetyltransferase
AL541_24840	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AL541_24840	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AL541_24845	COG0218	Necessary for normal cell division and for the maintenance of normal septation
AL541_24875	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AL541_24880	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AL541_24890	COG2204	response regulator
AL541_24895	COG3852	Histidine kinase
AL541_24905	COG0174	glutamine synthetase
AL541_24915	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AL541_24925	COG1295	ribonuclease BN
AL541_24930	COG1490	D-aminoacyl-tRNA deacylase activity
AL541_24935	COG0456	acetyltransferase
AL541_24945	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
AL541_24950	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AL541_24955	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
AL541_24960	COG3031	protein transport across the cell outer membrane
AL541_24970	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AL541_24975	COG1459	type II secretion system
AL541_24980	COG2165	general secretion pathway protein
AL541_24985	COG2165	general secretion pathway protein
AL541_24990	COG2165	general secretion pathway protein
AL541_24995	COG4795	General secretion pathway protein
AL541_25000	COG3156	type II secretion system protein K
AL541_25005	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
AL541_25010	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
AL541_25020	COG1218	3'(2'),5'-bisphosphate nucleotidase
AL541_25025	COG0494	nUDIX hydrolase
AL541_25035	COG1040	competence protein
AL541_25050	COG2183	response to ionizing radiation
AL541_25060	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AL541_25070	COG0745	RESPONSE REGULATOR receiver
AL541_25075	COG2205	protein histidine kinase activity
AL541_25080	COG2233	PERMEase
AL541_25085	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AL541_25090	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AL541_25095	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AL541_25100	COG1758	RNA polymerase activity
AL541_25105	COG0194	GDP metabolic process
AL541_25125	COG0848	biopolymer transport protein
AL541_25130	COG0811	peptide transport
AL541_25155	COG4174	ABC transporter (Permease)
AL541_25160	COG4239	(ABC) transporter, permease
AL541_25165	COG0747	negative chemotaxis
AL541_25170	COG0444	Belongs to the ABC transporter superfamily
AL541_25175	COG4608	Belongs to the ABC transporter superfamily
AL541_25185	COG1561	YicC-like family, N-terminal region
AL541_25195	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
AL541_25205	COG1560	Kdo2-lipid A biosynthetic process
AL541_25210	COG1309	transcriptional regulator
AL541_25215	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AL541_25230	COG2003	Belongs to the UPF0758 family
AL541_25255	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AL541_25270	COG0463	Glycosyl transferase, family 2
AL541_25275	COG0859	PFAM glycosyl transferase family 9
AL541_25280	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AL541_25285	COG3642	lipopolysaccharide core region biosynthetic process
AL541_25315	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AL541_25325	COG1028	Short-chain dehydrogenase reductase Sdr
AL541_25330	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AL541_25345	COG1519	Transferase
AL541_25350	COG0859	PFAM glycosyl transferase family 9
AL541_25360	COG1560	Kdo2-lipid A biosynthetic process
AL541_25370	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AL541_25430	COG1215	transferase activity, transferring glycosyl groups
AL541_25440	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
AL541_25445	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AL541_25465	COG1482	cell wall glycoprotein biosynthetic process
AL541_25480	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AL541_25500	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
AL541_25505	COG0149	triose-phosphate isomerase activity