locus-tag	class	description
J6320_00005	COG0247	lactate metabolic process
J6320_00005	COG0277	FAD linked oxidase domain protein
J6320_00020	COG1024	Enoyl-CoA hydratase
J6320_00025	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
J6320_00030	COG1960	acyl-CoA dehydrogenase activity
J6320_00040	COG0183	Belongs to the thiolase family
J6320_00055	COG1024	Enoyl-CoA hydratase
J6320_00060	COG1024	Enoyl-CoA hydratase
J6320_00070	COG1028	Short-chain dehydrogenase reductase Sdr
J6320_00075	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
J6320_00080	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
J6320_00085	COG1845	cytochrome c oxidase, subunit III
J6320_00090	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
J6320_00095	COG0109	protoheme IX farnesyltransferase activity
J6320_00100	COG0446	pyridine nucleotide-disulphide oxidoreductase
J6320_00100	COG1902	pentaerythritol trinitrate reductase activity
J6320_00115	COG1012	belongs to the aldehyde dehydrogenase family
J6320_00125	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
J6320_00155	COG1126	abc transporter atp-binding protein
J6320_00160	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J6320_00165	COG4215	(ABC) transporter
J6320_00170	COG4160	amino acid transport
J6320_00240	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
J6320_00245	COG2176	DNA-directed DNA polymerase activity
J6320_00250	COG0517	IMP dehydrogenase activity
J6320_00255	COG2186	Transcriptional regulator
J6320_00260	COG2186	Transcriptional regulator
J6320_00305	COG1917	Cupin 2, conserved barrel domain protein
J6320_00315	COG0800	Aldolase
J6320_00325	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
J6320_00335	COG2847	Copper chaperone PCu(A)C
J6320_00395	COG0814	amino acid
J6320_00405	COG0243	molybdopterin cofactor binding
J6320_00430	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
J6320_00430	COG1116	anion transmembrane transporter activity
J6320_00440	COG1116	anion transmembrane transporter activity
J6320_00445	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
J6320_00445	COG2146	nitrite reductase [NAD(P)H] activity
J6320_00495	COG2815	serine threonine protein kinase
J6320_00495	COG0515	serine threonine protein kinase
J6320_00530	COG0631	protein serine/threonine phosphatase activity
J6320_00600	COG0420	3'-5' exonuclease activity
J6320_00605	COG0419	ATPase involved in DNA repair
J6320_00615	COG3040	lipid binding
J6320_00625	COG1288	antiporter activity
J6320_00635	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
J6320_00650	COG2425	protein containing a von Willebrand factor type A (vWA) domain
J6320_00665	COG0583	DNA-binding transcription factor activity
J6320_00670	COG0277	FAD linked oxidase domain protein
J6320_00685	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
J6320_00755	COG5001	Diguanylate cyclase
J6320_00765	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
J6320_00775	COG2116	formate transmembrane transporter activity
J6320_00795	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
J6320_00830	COG3118	belongs to the thioredoxin family
J6320_00860	COG2271	Major facilitator Superfamily
J6320_00865	COG3851	Histidine kinase
J6320_00870	COG2197	response regulator
J6320_00880	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
J6320_00885	COG0583	DNA-binding transcription factor activity
J6320_00890	COG0243	molybdopterin cofactor binding
J6320_00905	COG0384	phenazine biosynthesis protein PhzF
J6320_00910	COG1794	racemase activity, acting on amino acids and derivatives
J6320_00940	COG1328	CTP reductase activity
J6320_01005	COG3550	peptidyl-serine autophosphorylation
J6320_01040	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
J6320_01070	COG0602	queuosine metabolic process
J6320_01080	COG2207	Transcriptional regulator
J6320_01090	COG0189	ligase activity
J6320_01090	COG4067	protein conserved in archaea
J6320_01100	COG3111	PFAM Bacterial OB fold (BOF) protein
J6320_01110	COG0725	ABC transporter, periplasmic molybdate-binding protein
J6320_01115	COG4149	molybdate abc transporter
J6320_01120	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
J6320_01130	COG2203	Gaf domain
J6320_01130	COG4251	negative regulation of phosphorylation
J6320_01130	COG5001	Diguanylate cyclase
J6320_01130	COG3706	GGDEF domain
J6320_01150	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
J6320_01155	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
J6320_01180	COG3140	Belongs to the UPF0181 family
J6320_01195	COG0583	DNA-binding transcription factor activity
J6320_01205	COG0023	Translation Initiation Factor
J6320_01215	COG1181	Belongs to the D-alanine--D-alanine ligase family
J6320_01225	COG0045	succinate-CoA ligase (ADP-forming) activity
J6320_01225	COG1042	CoA-binding domain protein
J6320_01225	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
J6320_01230	COG0583	DNA-binding transcription factor activity
J6320_01245	COG3447	MASE1 domain protein
J6320_01245	COG5001	Diguanylate cyclase
J6320_01245	COG5002	protein histidine kinase activity
J6320_01250	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
J6320_01255	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
J6320_01260	COG1984	allophanate hydrolase subunit 2
J6320_01270	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
J6320_01275	COG4181	ATPase activity
J6320_01285	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
J6320_01290	COG3300	MHYT domain
J6320_01290	COG5001	Diguanylate cyclase
J6320_01300	COG0484	heat shock protein binding
J6320_01325	COG4533	DNA binding
J6320_01335	COG2050	protein possibly involved in aromatic compounds catabolism
J6320_01350	COG2067	long-chain fatty acid transport protein
J6320_01380	COG0737	Belongs to the 5'-nucleotidase family
J6320_01385	COG3593	DNA synthesis involved in DNA repair
J6320_01395	COG0583	DNA-binding transcription factor activity
J6320_01400	COG2116	formate transmembrane transporter activity
J6320_01405	COG2353	YceI-like domain
J6320_01410	COG3038	cytochrome b561
J6320_01430	COG0513	Belongs to the DEAD box helicase family
J6320_01435	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
J6320_01445	COG0840	transmembrane signaling receptor activity
J6320_01450	COG0546	phosphoglycolate phosphatase activity
J6320_01465	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J6320_01475	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
J6320_01485	COG2207	Transcriptional regulator
J6320_01500	COG1126	abc transporter atp-binding protein
J6320_01510	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J6320_01515	COG0765	amino acid transport
J6320_01520	COG2200	EAL domain
J6320_01520	COG2203	Gaf domain
J6320_01520	COG2199	diguanylate cyclase activity
J6320_01535	COG1609	Transcriptional regulator
J6320_01540	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
J6320_01540	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
J6320_01545	COG1105	Belongs to the carbohydrate kinase PfkB family
J6320_01550	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
J6320_01550	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J6320_01550	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J6320_01580	COG0404	The glycine cleavage system catalyzes the degradation of glycine
J6320_01590	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
J6320_01595	COG0509	glycine decarboxylation via glycine cleavage system
J6320_01605	COG0346	lactoylglutathione lyase activity
J6320_01610	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
J6320_01615	COG0583	DNA-binding transcription factor activity
J6320_01620	COG0697	spore germination
J6320_01625	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
J6320_01655	COG2176	DNA-directed DNA polymerase activity
J6320_01700	COG0242	peptide deformylase activity
J6320_01735	COG2239	Acts as a magnesium transporter
J6320_01755	COG0346	lactoylglutathione lyase activity
J6320_01760	COG1902	pentaerythritol trinitrate reductase activity
J6320_01780	COG5642	Protein of unknown function (DUF2384)
J6320_01785	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
J6320_01820	COG2076	Multidrug Resistance protein
J6320_01840	COG2962	Rard protein
J6320_01855	COG0784	Response regulator, receiver
J6320_01855	COG0835	chemotaxis
J6320_01860	COG2197	response regulator
J6320_01870	COG3706	GGDEF domain
J6320_01875	COG2197	response regulator
J6320_01880	COG5001	Diguanylate cyclase
J6320_01880	COG3300	MHYT domain
J6320_01885	COG2205	protein histidine kinase activity
J6320_01885	COG0784	Response regulator, receiver
J6320_01890	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
J6320_01915	COG0456	acetyltransferase
J6320_01915	COG1214	PFAM Peptidase M22, glycoprotease
J6320_01925	COG3069	C4-dicarboxylate transmembrane transporter activity
J6320_01950	COG3111	PFAM Bacterial OB fold (BOF) protein
J6320_01955	COG1597	lipid kinase activity
J6320_01960	COG0583	DNA-binding transcription factor activity
J6320_01965	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
J6320_01995	COG0714	Associated with various cellular activities
J6320_02000	COG0641	radical SAM
J6320_02005	COG3119	arylsulfatase activity
J6320_02015	COG3119	arylsulfatase activity
J6320_02020	COG0745	RESPONSE REGULATOR receiver
J6320_02035	COG0784	Response regulator, receiver
J6320_02035	COG2198	Histidine kinase
J6320_02035	COG2205	protein histidine kinase activity
J6320_02040	COG1879	ABC-type sugar transport system periplasmic component
J6320_02045	COG1803	Methylglyoxal synthase
J6320_02050	COG0210	DNA helicase
J6320_02055	COG1289	transmembrane transporter activity
J6320_02095	COG0789	Transcriptional regulator
J6320_02100	COG4604	ABC transporter, ATP-binding protein
J6320_02105	COG4605	iron ion homeostasis
J6320_02110	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J6320_02115	COG4607	ABC-type enterochelin transport system periplasmic component
J6320_02125	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
J6320_02135	COG1609	Transcriptional regulator
J6320_02140	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J6320_02145	COG1879	ABC-type sugar transport system periplasmic component
J6320_02150	COG1172	Belongs to the binding-protein-dependent transport system permease family
J6320_02155	COG1129	ABC transporter
J6320_02160	COG1869	D-ribose catabolic process
J6320_02165	COG5001	Diguanylate cyclase
J6320_02220	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
J6320_02230	COG2205	protein histidine kinase activity
J6320_02230	COG0784	Response regulator, receiver
J6320_02245	COG0330	HflC and HflK could
J6320_02260	COG4175	Glycine betaine
J6320_02260	COG0517	IMP dehydrogenase activity
J6320_02265	COG4176	ABC-type proline glycine betaine transport system permease component
J6320_02280	COG1012	belongs to the aldehyde dehydrogenase family
J6320_02285	COG1309	transcriptional regulator
J6320_02295	COG1028	Short-chain dehydrogenase reductase Sdr
J6320_02310	COG1024	Enoyl-CoA hydratase
J6320_02315	COG1960	acyl-CoA dehydrogenase activity
J6320_02325	COG0183	Belongs to the thiolase family
J6320_02335	COG1960	acyl-CoA dehydrogenase activity
J6320_02340	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
J6320_02365	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
J6320_02365	COG3264	Mechanosensitive ion channel
J6320_02375	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J6320_02380	COG1271	oxidase subunit
J6320_02385	COG1294	oxidase, subunit
J6320_02395	COG0384	phenazine biosynthesis protein PhzF
J6320_02400	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
J6320_02410	COG3527	Alpha-acetolactate decarboxylase
J6320_02425	COG0500	methyltransferase
J6320_02455	COG1022	Amp-dependent synthetase and ligase
J6320_02480	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
J6320_02485	COG1263	PTS System
J6320_02485	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J6320_02490	COG1486	melibiose metabolic process
J6320_02495	COG2188	Transcriptional regulator
J6320_02500	COG1320	monovalent cation:proton antiporter activity
J6320_02505	COG2212	antiporter activity
J6320_02510	COG1863	multisubunit Na H antiporter MnhE subunit
J6320_02515	COG0651	ATP synthesis coupled electron transport
J6320_02520	COG1006	Multisubunit Na H antiporter MnhC subunit
J6320_02525	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
J6320_02525	COG2111	Na H antiporter
J6320_02535	COG0589	response to stress
J6320_02540	COG4221	oxidoreductase activity
J6320_02545	COG0583	DNA-binding transcription factor activity
J6320_02555	COG2814	Major facilitator Superfamily
J6320_02615	COG1522	sequence-specific DNA binding
J6320_02650	COG0515	serine threonine protein kinase
J6320_02675	COG3501	Rhs element vgr protein
J6320_02715	COG0739	heme binding
J6320_02725	COG1120	ATPase activity
J6320_02730	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J6320_02735	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J6320_02760	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
J6320_02760	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
J6320_02775	COG4989	oxidoreductase activity
J6320_02790	COG0038	chloride channel
J6320_02825	COG2897	thiosulfate sulfurtransferase activity
J6320_02835	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
J6320_02840	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
J6320_02850	COG2814	Major facilitator Superfamily
J6320_02855	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
J6320_02865	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
J6320_02875	COG0840	transmembrane signaling receptor activity
J6320_02895	COG2195	Cleaves the N-terminal amino acid of tripeptides
J6320_02910	COG2197	response regulator
J6320_02915	COG3850	Histidine kinase
J6320_02920	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
J6320_02930	COG0243	molybdopterin cofactor binding
J6320_02940	COG3005	denitrification pathway
J6320_02950	COG3243	poly(R)-hydroxyalkanoic acid synthase
J6320_02960	COG0183	Belongs to the thiolase family
J6320_02970	COG1280	lysine exporter protein (LysE YggA)
J6320_02980	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
J6320_02985	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
J6320_03030	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J6320_03035	COG1846	Transcriptional regulator
J6320_03040	COG0784	Response regulator, receiver
J6320_03040	COG2205	protein histidine kinase activity
J6320_03045	COG1879	ABC-type sugar transport system periplasmic component
J6320_03050	COG2827	Endonuclease containing a URI domain
J6320_03055	COG3132	Protein of unknown function, DUF480
J6320_03095	COG0583	DNA-binding transcription factor activity
J6320_03105	COG0531	amino acid
J6320_03120	COG2205	protein histidine kinase activity
J6320_03125	COG0745	RESPONSE REGULATOR receiver
J6320_03150	COG1566	PFAM secretion protein HlyD family protein
J6320_03155	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
J6320_03160	COG2239	Acts as a magnesium transporter
J6320_03165	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
J6320_03170	COG0402	S-adenosylhomocysteine deaminase activity
J6320_03180	COG1418	mRNA catabolic process
J6320_03190	COG2814	Major facilitator Superfamily
J6320_03200	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
J6320_03220	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
J6320_03235	COG0745	RESPONSE REGULATOR receiver
J6320_03250	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
J6320_03255	COG2194	sulfuric ester hydrolase activity
J6320_03275	COG4667	esterase of the alpha-beta hydrolase superfamily
J6320_03280	COG1741	Belongs to the pirin family
J6320_03285	COG1278	Cold shock
J6320_03300	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
J6320_03305	COG0678	peroxiredoxin activity
J6320_03305	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
J6320_03315	COG1686	Belongs to the peptidase S11 family
J6320_03320	COG0625	glutathione transferase activity
J6320_03330	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
J6320_03335	COG1621	beta-fructofuranosidase activity
J6320_03340	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J6320_03345	COG1263	PTS System
J6320_03345	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J6320_03365	COG1028	Short-chain dehydrogenase reductase Sdr
J6320_03380	COG3746	phosphate-selective porin O and P
J6320_03400	COG0583	DNA-binding transcription factor activity
J6320_03405	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
J6320_03405	COG2207	Transcriptional regulator
J6320_03410	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J6320_03430	COG0513	Belongs to the DEAD box helicase family
J6320_03440	COG0583	DNA-binding transcription factor activity
J6320_03480	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J6320_03485	COG0006	proline dipeptidase activity
J6320_03490	COG3608	succinylglutamate desuccinylase aspartoacylase
J6320_03495	COG1522	sequence-specific DNA binding
J6320_03500	COG1012	belongs to the aldehyde dehydrogenase family
J6320_03505	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
J6320_03510	COG3122	Protein conserved in bacteria
J6320_03525	COG0583	DNA-binding transcription factor activity
J6320_03530	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
J6320_03535	COG0252	asparaginase activity
J6320_03540	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
J6320_03555	COG2197	response regulator
J6320_03585	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
J6320_03615	COG3842	ATPase activity
J6320_03625	COG1309	transcriptional regulator
J6320_03660	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
J6320_03665	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
J6320_03695	COG0583	DNA-binding transcription factor activity
J6320_03705	COG4948	Mandelate Racemase Muconate Lactonizing
J6320_03735	COG1342	Belongs to the UPF0251 family
J6320_03740	COG4176	ABC-type proline glycine betaine transport system permease component
J6320_03745	COG4175	Glycine betaine
J6320_03745	COG3448	diguanylate cyclase activity
J6320_03750	COG3015	lipoprotein NlpE involved in copper resistance
J6320_03755	COG3713	MltA-interacting MipA family protein
J6320_03770	COG0583	DNA-binding transcription factor activity
J6320_03795	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
J6320_03805	COG1335	isochorismatase
J6320_03820	COG1349	DNA-binding transcription factor activity
J6320_03835	COG0531	amino acid
J6320_03840	COG4302	ethanolamine ammonia-lyase activity
J6320_03845	COG4303	Ethanolamine ammonia lyase large subunit
J6320_03855	COG1309	transcriptional regulator
J6320_03875	COG1280	lysine exporter protein (LysE YggA)
J6320_03885	COG0459	protein refolding
J6320_03890	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
J6320_03895	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
J6320_03910	COG1304	FMN binding
J6320_03935	COG1256	bacterial-type flagellum assembly
J6320_03935	COG4786	Flagellar basal body rod
J6320_03945	COG1706	bacterial-type flagellum-dependent cell motility
J6320_03950	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
J6320_03955	COG4786	Flagellar basal body rod
J6320_03960	COG4787	bacterial-type flagellum-dependent cell motility
J6320_03975	COG1558	bacterial-type flagellum-dependent cell motility
J6320_03980	COG1815	bacterial-type flagellum-dependent cell motility
J6320_04000	COG0741	lytic transglycosylase activity
J6320_04005	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
J6320_04025	COG1760	l-serine dehydratase
J6320_04040	COG0583	DNA-binding transcription factor activity
J6320_04050	COG2866	Carboxypeptidase
J6320_04055	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
J6320_04065	COG2990	Protein conserved in bacteria
J6320_04090	COG3842	ATPase activity
J6320_04095	COG1840	ABC-type Fe3 transport system, periplasmic component
J6320_04105	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
J6320_04115	COG1609	Transcriptional regulator
J6320_04145	COG3240	lipase activity
J6320_04150	COG1309	transcriptional regulator
J6320_04165	COG0577	efflux transmembrane transporter activity
J6320_04165	COG1136	(ABC) transporter
J6320_04170	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J6320_04175	COG2067	long-chain fatty acid transport protein
J6320_04185	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
J6320_04200	COG1011	Hydrolase
J6320_04245	COG0110	maltose O-acetyltransferase activity
J6320_04250	COG1765	OsmC-like protein
J6320_04255	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
J6320_04255	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
J6320_04270	COG3046	protein related to deoxyribodipyrimidine photolyase
J6320_04275	COG0415	Belongs to the DNA photolyase family
J6320_04280	COG3706	GGDEF domain
J6320_04295	COG3706	GGDEF domain
J6320_04330	COG3033	Beta-eliminating lyase
J6320_04340	COG1271	oxidase subunit
J6320_04345	COG1294	oxidase, subunit
J6320_04355	COG0579	oxidoreductase
J6320_04385	COG4191	Histidine kinase
J6320_04410	COG0583	DNA-binding transcription factor activity
J6320_04430	COG0189	ligase activity
J6320_04435	COG0189	ligase activity
J6320_04435	COG4067	protein conserved in archaea
J6320_04450	COG0010	Belongs to the arginase family
J6320_04455	COG2814	Major facilitator Superfamily
J6320_04460	COG1770	oligopeptidase
J6320_04475	COG1108	ABC-type Mn2 Zn2 transport systems permease components
J6320_04480	COG1121	(ABC) transporter
J6320_04485	COG0803	Belongs to the bacterial solute-binding protein 9 family
J6320_04525	COG0848	biopolymer transport protein
J6320_04530	COG0811	peptide transport
J6320_04535	COG0811	peptide transport
J6320_04555	COG0745	RESPONSE REGULATOR receiver
J6320_04560	COG0584	glycerophosphoryl diester phosphodiesterase
J6320_04570	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
J6320_04630	COG1901	pseudouridine methyltransferase
J6320_04635	COG0312	modulator of DNA gyrase
J6320_04640	COG0312	modulator of DNA gyrase
J6320_04645	COG0351	phosphomethylpyrimidine kinase
J6320_04650	COG1116	anion transmembrane transporter activity
J6320_04655	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
J6320_04660	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
J6320_04665	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
J6320_04685	COG0243	molybdopterin cofactor binding
J6320_04690	COG3005	denitrification pathway
J6320_04695	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
J6320_04700	COG1028	Short-chain dehydrogenase reductase Sdr
J6320_04715	COG0456	acetyltransferase
J6320_04735	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J6320_04740	COG1929	Belongs to the glycerate kinase type-1 family
J6320_04745	COG2610	gluconate transmembrane transporter activity
J6320_04750	COG3835	regulator
J6320_04810	COG3047	cAMP biosynthetic process
J6320_04815	COG1357	PFAM Pentapeptide repeats (8 copies)
J6320_04845	COG2375	cellular response to nickel ion
J6320_04850	COG0583	DNA-binding transcription factor activity
J6320_04855	COG2162	N-hydroxyarylamine O-acetyltransferase activity
J6320_04860	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
J6320_04875	COG2199	diguanylate cyclase activity
J6320_04885	COG0561	phosphatase activity
J6320_04890	COG0583	DNA-binding transcription factor activity
J6320_04905	COG0564	pseudouridine synthase activity
J6320_04910	COG0534	Mate efflux family protein
J6320_04925	COG3123	guanosine phosphorylase activity
J6320_04940	COG0596	Alpha beta hydrolase
J6320_04965	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
J6320_04975	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
J6320_04980	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
J6320_04980	COG2169	Transcriptional regulator
J6320_04990	COG2259	Doxx family
J6320_04995	COG1741	Belongs to the pirin family
J6320_05015	COG0363	glucosamine-6-phosphate deaminase activity
J6320_05025	COG0786	glutamate:sodium symporter activity
J6320_05030	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J6320_05035	COG1131	(ABC) transporter
J6320_05045	COG0786	glutamate:sodium symporter activity
J6320_05065	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
J6320_05075	COG3279	Response regulator of the LytR AlgR family
J6320_05080	COG3275	phosphorelay sensor kinase activity
J6320_05100	COG1136	(ABC) transporter
J6320_05110	COG0772	Belongs to the SEDS family
J6320_05135	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
J6320_05135	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
J6320_05145	COG0444	Belongs to the ABC transporter superfamily
J6320_05150	COG4608	Belongs to the ABC transporter superfamily
J6320_05175	COG1444	tRNA N-acetyltransferase activity
J6320_05195	COG3340	Belongs to the peptidase S51 family
J6320_05200	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
J6320_05205	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J6320_05205	COG1263	PTS System
J6320_05210	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
J6320_05225	COG4166	transmembrane transport
J6320_05275	COG0259	pyridoxamine-phosphate oxidase activity
J6320_05300	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
J6320_05335	COG1132	(ABC) transporter
J6320_05345	COG0513	Belongs to the DEAD box helicase family
J6320_05350	COG2258	MOSC domain
J6320_05395	COG3634	alkyl hydroperoxide reductase activity
J6320_05405	COG1846	Transcriptional regulator
J6320_05410	COG1764	response to oxidative stress
J6320_05440	COG0577	efflux transmembrane transporter activity
J6320_05445	COG1136	(ABC) transporter
J6320_05460	COG0463	Glycosyl transferase, family 2
J6320_05480	COG0826	peptidase U32
J6320_05505	COG1653	transport
J6320_05510	COG0019	diaminopimelate decarboxylase activity
J6320_05515	COG4264	IucA IucC family
J6320_05545	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
J6320_05550	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J6320_05555	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J6320_05560	COG1120	ATPase activity
J6320_05565	COG0840	transmembrane signaling receptor activity
J6320_05570	COG0612	Peptidase, M16
J6320_05580	COG0739	heme binding
J6320_05595	COG2814	Major facilitator Superfamily
J6320_05605	COG1609	Transcriptional regulator
J6320_05610	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
J6320_05625	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
J6320_05625	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
J6320_05635	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
J6320_05640	COG1609	Transcriptional regulator
J6320_05650	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
J6320_05690	COG1760	l-serine dehydratase
J6320_05700	COG4580	involved in the transport of maltose and maltodextrins
J6320_05720	COG2356	endonuclease I
J6320_05740	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
J6320_05745	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
J6320_05750	COG1162	GTPase activity
J6320_05755	COG1263	PTS System
J6320_05755	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J6320_05760	COG1999	signal sequence binding
J6320_05775	COG2909	trisaccharide binding
J6320_05780	COG0058	SHG alpha-glucan phosphorylase activity
J6320_05785	COG1640	4-alpha-glucanotransferase
J6320_05790	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
J6320_05795	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
J6320_05800	COG0366	Alpha amylase catalytic
J6320_05815	COG3366	ferrous iron transmembrane transporter activity
J6320_05820	COG0700	Nucleoside recognition
J6320_05825	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
J6320_05830	COG3339	Conserved Protein
J6320_05840	COG1301	dicarboxylic acid transport
J6320_05850	COG0583	DNA-binding transcription factor activity
J6320_05870	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
J6320_05875	COG1596	polysaccharide export
J6320_05890	COG2095	MarC family integral membrane protein
J6320_05895	COG4667	esterase of the alpha-beta hydrolase superfamily
J6320_05900	COG3397	chitin binding
J6320_05905	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
J6320_05910	COG0415	Belongs to the DNA photolyase family
J6320_05920	COG1054	Belongs to the UPF0176 family
J6320_05930	COG1686	Belongs to the peptidase S11 family
J6320_05960	COG4628	conserved protein (DUF2132)
J6320_05980	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
J6320_05985	COG0628	permease
J6320_06025	COG2814	Major facilitator Superfamily
J6320_06035	COG0454	-acetyltransferase
J6320_06045	COG0745	RESPONSE REGULATOR receiver
J6320_06050	COG2205	protein histidine kinase activity
J6320_06065	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
J6320_06070	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
J6320_06075	COG1882	Formate acetyltransferase
J6320_06105	COG1360	Flagellar Motor Protein
J6320_06110	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
J6320_06115	COG1191	sigma factor activity
J6320_06120	COG1580	Controls the rotational direction of flagella during chemotaxis
J6320_06135	COG1516	flagellar protein fliS
J6320_06140	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
J6320_06150	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
J6320_06165	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
J6320_06175	COG1987	bacterial-type flagellum assembly
J6320_06215	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
J6320_06275	COG0346	lactoylglutathione lyase activity
J6320_06300	COG0745	RESPONSE REGULATOR receiver
J6320_06325	COG5001	Diguanylate cyclase
J6320_06325	COG3300	MHYT domain
J6320_06330	COG0156	8-amino-7-oxononanoate synthase activity
J6320_06335	COG1063	alcohol dehydrogenase
J6320_06370	COG0668	transmembrane transport
J6320_06380	COG1304	FMN binding
J6320_06385	COG1620	l-lactate permease
J6320_06390	COG0583	DNA-binding transcription factor activity
J6320_06395	COG1505	serine-type exopeptidase activity
J6320_06400	COG4172	Belongs to the ABC transporter superfamily
J6320_06410	COG1067	ATP-dependent peptidase activity
J6320_06420	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
J6320_06440	COG1247	-acetyltransferase
J6320_06445	COG0437	4 iron, 4 sulfur cluster binding
J6320_06450	COG0348	domain, Protein
J6320_06470	COG1122	ATPase activity
J6320_06475	COG4720	Psort location CytoplasmicMembrane, score
J6320_06480	COG1566	PFAM secretion protein HlyD family protein
J6320_06505	COG0813	purine-nucleoside phosphorylase activity
J6320_06510	COG3272	Protein of unknown function (DUF1722)
J6320_06515	COG0789	Transcriptional regulator
J6320_06520	COG0415	Belongs to the DNA photolyase family
J6320_06525	COG1376	ErfK ybiS ycfS ynhG family protein
J6320_06525	COG1388	LysM domain
J6320_06535	COG0513	Belongs to the DEAD box helicase family
J6320_06540	COG1770	oligopeptidase
J6320_06545	COG4771	TonB-dependent receptor
J6320_06575	COG0573	inorganic phosphate transmembrane transporter activity
J6320_06580	COG0581	inorganic phosphate transmembrane transporter activity
J6320_06585	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
J6320_06620	COG0714	Associated with various cellular activities
J6320_06635	COG2197	response regulator
J6320_06670	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
J6320_06675	COG1120	ATPase activity
J6320_06680	COG4774	siderophore transport
J6320_06685	COG1132	(ABC) transporter
J6320_06690	COG2205	protein histidine kinase activity
J6320_06690	COG2205	protein histidine kinase activity
J6320_06695	COG0745	RESPONSE REGULATOR receiver
J6320_06700	COG0569	domain protein
J6320_06705	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
J6320_06710	COG0583	DNA-binding transcription factor activity
J6320_06715	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
J6320_06725	COG1012	belongs to the aldehyde dehydrogenase family
J6320_06730	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
J6320_06735	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
J6320_06745	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
J6320_06750	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
J6320_06780	COG2084	Dehydrogenase
J6320_06785	COG0753	catalase activity
J6320_06795	COG2130	NADP-dependent
J6320_06800	COG1309	transcriptional regulator
J6320_06805	COG3097	Belongs to the UPF0267 family
J6320_06845	COG0489	protein tyrosine kinase activity
J6320_06845	COG3206	protein involved in exopolysaccharide biosynthesis
J6320_06860	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
J6320_06865	COG3842	ATPase activity
J6320_06875	COG1175	transmembrane transport
J6320_06880	COG3833	ABC-type maltose transport systems, permease component
J6320_06910	COG2354	Protein conserved in bacteria
J6320_06915	COG0418	dihydroorotase activity
J6320_06920	COG0401	homolog of Blt101
J6320_06925	COG0633	Ferredoxin
J6320_06925	COG0633	Ferredoxin
J6320_06925	COG3217	Mosc domain protein beta barrel domain protein
J6320_06925	COG3217	Mosc domain protein beta barrel domain protein
J6320_06935	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
J6320_06975	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
J6320_06980	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J6320_06990	COG0848	biopolymer transport protein
J6320_06995	COG0811	peptide transport
J6320_07000	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
J6320_07010	COG3721	Heme iron utilization protein
J6320_07015	COG0748	coenzyme F420 binding
J6320_07025	COG0835	chemotaxis
J6320_07025	COG0784	Response regulator, receiver
J6320_07030	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
J6320_07035	COG0534	Mate efflux family protein
J6320_07040	COG0444	Belongs to the ABC transporter superfamily
J6320_07045	COG4608	Belongs to the ABC transporter superfamily
J6320_07050	COG0747	negative chemotaxis
J6320_07060	COG1349	DNA-binding transcription factor activity
J6320_07070	COG3395	kinase activity
J6320_07075	COG0235	Class ii aldolase
J6320_07080	COG3622	Belongs to the hyi family
J6320_07085	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
J6320_07090	COG2610	gluconate transmembrane transporter activity
J6320_07110	COG0583	DNA-binding transcription factor activity
J6320_07115	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
J6320_07120	COG4934	collagen metabolic process
J6320_07130	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
J6320_07135	COG0789	Transcriptional regulator
J6320_07140	COG0366	Alpha amylase catalytic
J6320_07160	COG2249	NAD(P)H dehydrogenase (quinone) activity
J6320_07170	COG0488	(ABC) transporter
J6320_07185	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J6320_07195	COG2067	long-chain fatty acid transport protein
J6320_07205	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
J6320_07230	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
J6320_07250	COG3383	formate dehydrogenase (NAD+) activity
J6320_07260	COG0842	Transport permease protein
J6320_07265	COG1131	(ABC) transporter
J6320_07280	COG1881	PFAM PEBP family protein
J6320_07290	COG0798	PFAM Bile acid sodium symporter
J6320_07305	COG1733	regulation of RNA biosynthetic process
J6320_07330	COG4989	oxidoreductase activity
J6320_07355	COG0814	amino acid
J6320_07370	COG3314	Sporulation integral membrane protein YlbJ
J6320_07390	COG0739	heme binding
J6320_07395	COG5001	Diguanylate cyclase
J6320_07400	COG0583	DNA-binding transcription factor activity
J6320_07405	COG2814	Major facilitator Superfamily
J6320_07420	COG0697	spore germination
J6320_07425	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
J6320_07435	COG0179	Fumarylacetoacetate (FAA) hydrolase
J6320_07455	COG1280	lysine exporter protein (LysE YggA)
J6320_07465	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
J6320_07470	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
J6320_07475	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
J6320_07480	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
J6320_07485	COG1845	cytochrome c oxidase, subunit III
J6320_07505	COG1612	heme a metabolic process
J6320_07510	COG0109	protoheme IX farnesyltransferase activity
J6320_07515	COG0545	Peptidyl-prolyl cis-trans isomerase
J6320_07545	COG1278	Cold shock
J6320_07550	COG3036	rescue of stalled ribosome
J6320_07555	COG2199	diguanylate cyclase activity
J6320_07570	COG1132	(ABC) transporter
J6320_07580	COG1538	Outer membrane efflux protein
J6320_07585	COG0784	Response regulator, receiver
J6320_07585	COG2205	protein histidine kinase activity
J6320_07615	COG0783	Belongs to the Dps family
J6320_07625	COG2133	pyrroloquinoline quinone binding
J6320_07630	COG1454	alcohol dehydrogenase
J6320_07635	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
J6320_07660	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
J6320_07665	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
J6320_07670	COG3186	Phenylalanine-4-hydroxylase
J6320_07695	COG3530	Putative quorum-sensing-regulated virulence factor
J6320_07725	COG1279	arginine transmembrane transporter activity
J6320_07735	COG0730	response to heat
J6320_07755	COG0513	Belongs to the DEAD box helicase family
J6320_07760	COG4628	conserved protein (DUF2132)
J6320_07770	COG0133	tryptophan synthase activity
J6320_07775	COG1278	Cold shock
J6320_07785	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
J6320_07795	COG0523	cobalamin synthesis protein
J6320_07800	COG0513	Belongs to the DEAD box helicase family
J6320_07825	COG1119	ATPase activity
J6320_07860	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
J6320_07865	COG0513	Belongs to the DEAD box helicase family
J6320_07875	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
J6320_07885	COG1073	alpha beta
J6320_07890	COG1073	alpha beta
J6320_07905	COG0436	Aminotransferase
J6320_07975	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
J6320_07980	COG0592	DNA-directed DNA polymerase activity
J6320_07990	COG0187	DNA topoisomerase II activity
J6320_08000	COG0071	Belongs to the small heat shock protein (HSP20) family
J6320_08005	COG3977	Valine--pyruvate aminotransferase
J6320_08010	COG0366	Alpha amylase catalytic
J6320_08025	COG2119	membrane
J6320_08035	COG0425	Belongs to the sulfur carrier protein TusA family
J6320_08050	COG0604	alcohol dehydrogenase
J6320_08055	COG0183	Belongs to the thiolase family
J6320_08065	COG1739	Uncharacterized protein family UPF0029
J6320_08110	COG0583	DNA-binding transcription factor activity
J6320_08115	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
J6320_08120	COG2960	long-chain fatty acid transporting porin activity
J6320_08125	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
J6320_08130	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J6320_08190	COG4166	transmembrane transport
J6320_08195	COG0601	transmembrane transport
J6320_08200	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J6320_08235	COG1609	Transcriptional regulator
J6320_08240	COG0583	DNA-binding transcription factor activity
J6320_08255	COG0129	dihydroxy-acid dehydratase activity
J6320_08260	COG3265	gluconokinase activity
J6320_08265	COG2610	gluconate transmembrane transporter activity
J6320_08270	COG0800	Aldolase
J6320_08275	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
J6320_08280	COG0583	DNA-binding transcription factor activity
J6320_08285	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
J6320_08290	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
J6320_08300	COG1522	sequence-specific DNA binding
J6320_08310	COG0742	ribosomal rna small subunit methyltransferase
J6320_08325	COG0589	response to stress
J6320_08330	COG1528	Iron-storage protein
J6320_08340	COG2081	HI0933 family
J6320_08370	COG1597	lipid kinase activity
J6320_08400	COG0628	permease
J6320_08415	COG1322	Protein conserved in bacteria
J6320_08420	COG2226	methyltransferase
J6320_08425	COG3165	ubiquinone biosynthetic process from chorismate
J6320_08430	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
J6320_08440	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
J6320_08445	COG0805	protein transport
J6320_08450	COG0084	hydrolase, TatD family'
J6320_08460	COG0456	acetyltransferase
J6320_08465	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
J6320_08465	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
J6320_08470	COG0218	Necessary for normal cell division and for the maintenance of normal septation
J6320_08500	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
J6320_08510	COG2204	response regulator
J6320_08515	COG3852	Histidine kinase
J6320_08525	COG0174	glutamine synthetase
J6320_08530	COG1217	gtp-binding protein TYPA
J6320_08535	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
J6320_08545	COG1295	ribonuclease BN
J6320_08550	COG1490	D-aminoacyl-tRNA deacylase activity
J6320_08555	COG0456	acetyltransferase
J6320_08565	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
J6320_08570	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
J6320_08575	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
J6320_08580	COG3031	protein transport across the cell outer membrane
J6320_08590	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
J6320_08595	COG1459	type II secretion system
J6320_08600	COG2165	general secretion pathway protein
J6320_08605	COG2165	general secretion pathway protein
J6320_08610	COG2165	general secretion pathway protein
J6320_08615	COG4795	General secretion pathway protein
J6320_08620	COG3156	type II secretion system protein K
J6320_08625	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
J6320_08630	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
J6320_08640	COG1218	3'(2'),5'-bisphosphate nucleotidase
J6320_08645	COG0494	nUDIX hydrolase
J6320_08655	COG1040	competence protein
J6320_08670	COG2183	response to ionizing radiation
J6320_08680	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
J6320_08700	COG2233	PERMEase
J6320_08705	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
J6320_08710	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
J6320_08720	COG1758	RNA polymerase activity
J6320_08725	COG0194	GDP metabolic process
J6320_08740	COG0848	biopolymer transport protein
J6320_08745	COG0811	peptide transport
J6320_08765	COG4174	ABC transporter (Permease)
J6320_08770	COG4239	(ABC) transporter, permease
J6320_08775	COG0747	negative chemotaxis
J6320_08780	COG0444	Belongs to the ABC transporter superfamily
J6320_08785	COG4608	Belongs to the ABC transporter superfamily
J6320_08795	COG1561	YicC-like family, N-terminal region
J6320_08805	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
J6320_08810	COG1560	Kdo2-lipid A biosynthetic process
J6320_08815	COG1309	transcriptional regulator
J6320_08825	COG0840	transmembrane signaling receptor activity
J6320_08830	COG2003	Belongs to the UPF0758 family
J6320_08855	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
J6320_08870	COG0463	Glycosyl transferase, family 2
J6320_08875	COG0859	PFAM glycosyl transferase family 9
J6320_08880	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
J6320_08885	COG3642	lipopolysaccharide core region biosynthetic process
J6320_08895	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
J6320_08920	COG2895	sulfate adenylyltransferase (ATP) activity
J6320_08925	COG0529	Catalyzes the synthesis of activated sulfate
J6320_08930	COG0175	sulfate reduction
J6320_08935	COG0471	metal ion transport
J6320_08935	COG3273	potassium ion transport
J6320_08940	COG1519	Transferase
J6320_08945	COG0859	PFAM glycosyl transferase family 9
J6320_08955	COG1560	Kdo2-lipid A biosynthetic process
J6320_08965	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
J6320_09000	COG0517	IMP dehydrogenase activity
J6320_09000	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
J6320_09045	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
J6320_09050	COG2877	3-deoxy-8-phosphooctulonate synthase activity
J6320_09055	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
J6320_09060	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
J6320_09065	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
J6320_09090	COG0438	transferase activity, transferring glycosyl groups
J6320_09100	COG0438	transferase activity, transferring glycosyl groups
J6320_09105	COG0438	transferase activity, transferring glycosyl groups
J6320_09110	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
J6320_09120	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
J6320_09150	COG0149	triose-phosphate isomerase activity
J6320_09180	COG1494	fructose-1,6-bisphosphatase
J6320_09190	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
J6320_09195	COG1575	Belongs to the MenA family. Type 1 subfamily
J6320_09205	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
J6320_09220	COG1609	Transcriptional regulator
J6320_09225	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
J6320_09230	COG0254	rRNA binding
J6320_09245	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
J6320_09250	COG0088	Forms part of the polypeptide exit tunnel
J6320_09260	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
J6320_09265	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
J6320_09270	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
J6320_09275	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
J6320_09285	COG0255	Belongs to the universal ribosomal protein uL29 family
J6320_09290	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
J6320_09300	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
J6320_09305	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
J6320_09315	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
J6320_09320	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
J6320_09335	COG1841	ribosomal large subunit assembly
J6320_09340	COG0200	Binds to the 23S rRNA
J6320_09345	COG0201	protein transport
J6320_09350	COG0257	Belongs to the bacterial ribosomal protein bL36 family
J6320_09355	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
J6320_09360	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
J6320_09370	COG0202	RNA polymerase activity
J6320_09375	COG0203	ribosomal protein L17
J6320_09385	COG0545	Peptidyl-prolyl cis-trans isomerase
J6320_09395	COG2153	protein acetylation
J6320_09400	COG0513	Belongs to the DEAD box helicase family
J6320_09415	COG1648	precorrin-2 dehydrogenase activity
J6320_09415	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
J6320_09420	COG0175	sulfate reduction
J6320_09425	COG2895	sulfate adenylyltransferase (ATP) activity
J6320_09435	COG0529	Catalyzes the synthesis of activated sulfate
J6320_09455	COG4181	ATPase activity
J6320_09470	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
J6320_09480	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
J6320_09485	COG0729	surface antigen
J6320_09495	COG2105	PFAM AIG2 family protein
J6320_09505	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
J6320_09510	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
J6320_09515	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
J6320_09520	COG0163	prenyltransferase activity
J6320_09525	COG4143	(ABC) transporter
J6320_09530	COG1178	ABC-type Fe3 transport system permease component
J6320_09535	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
J6320_09540	COG0583	DNA-binding transcription factor activity
J6320_09545	COG1902	pentaerythritol trinitrate reductase activity
J6320_09560	COG2358	TRAP transporter, solute receptor (TAXI family
J6320_09580	COG0142	geranyltranstransferase activity
J6320_09585	COG0261	This protein binds to 23S rRNA in the presence of protein L20
J6320_09595	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
J6320_09600	COG2966	Psort location CytoplasmicMembrane, score
J6320_09615	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
J6320_09620	COG2967	ApaG domain
J6320_09625	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
J6320_09630	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
J6320_09635	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
J6320_09640	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
J6320_09645	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
J6320_09665	COG0473	3-isopropylmalate dehydrogenase activity
J6320_09670	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
J6320_09690	COG0583	DNA-binding transcription factor activity
J6320_09700	COG0028	Belongs to the TPP enzyme family
J6320_09705	COG0440	acetolactate synthase activity
J6320_09720	COG0469	pyruvate kinase activity
J6320_09725	COG1349	DNA-binding transcription factor activity
J6320_09730	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
J6320_09740	COG2376	Dihydroxyacetone kinase
J6320_09745	COG1461	Dihydroxyacetone kinase
J6320_09760	COG3722	fumarate hydratase activity
J6320_09770	COG2213	PTS system mannitol-specific
J6320_09770	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
J6320_09880	COG0358	DNA primase activity
J6320_09885	COG1610	YqeY-like protein
J6320_09890	COG0828	Belongs to the bacterial ribosomal protein bS21 family
J6320_09895	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
J6320_09900	COG0596	Alpha beta hydrolase
J6320_09905	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
J6320_09910	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
J6320_09915	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
J6320_09920	COG1968	undecaprenyl-diphosphatase activity
J6320_09930	COG3267	Type II secretory pathway component ExeA
J6320_09930	COG3409	Peptidoglycan-binding domain 1 protein
J6320_09940	COG0405	Gamma-glutamyltransferase
J6320_09945	COG4991	sh3 domain protein
J6320_09950	COG0306	phosphate transporter
J6320_09955	COG1392	Phosphate transport regulator
J6320_09960	COG3025	triphosphatase activity
J6320_09975	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
J6320_09980	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
J6320_09980	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
J6320_09985	COG1538	Outer membrane efflux protein
J6320_09990	COG0494	nUDIX hydrolase
J6320_09995	COG3151	Protein conserved in bacteria
J6320_10005	COG3150	esterase
J6320_10015	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
J6320_10020	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
J6320_10030	COG3105	Protein conserved in bacteria
J6320_10035	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
J6320_10045	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
J6320_10050	COG0723	plastoquinol--plastocyanin reductase activity
J6320_10055	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
J6320_10060	COG2857	Cytochrome c1
J6320_10065	COG0625	glutathione transferase activity
J6320_10070	COG2969	positive regulation of protein catabolic process
J6320_10075	COG2823	Periplasmic or secreted lipoprotein
J6320_10095	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
J6320_10110	COG3116	cell division
J6320_10115	COG0768	penicillin binding
J6320_10120	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
J6320_10130	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
J6320_10135	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
J6320_10140	COG0772	Belongs to the SEDS family
J6320_10155	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
J6320_10160	COG0849	cell division
J6320_10165	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
J6320_10170	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
J6320_10180	COG0653	protein targeting
J6320_10185	COG0494	nUDIX hydrolase
J6320_10195	COG0505	Belongs to the CarA family
J6320_10215	COG0730	response to heat
J6320_10220	COG0583	DNA-binding transcription factor activity
J6320_10225	COG2860	membrane
J6320_10240	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
J6320_10250	COG0493	'glutamate synthase
J6320_10255	COG0070	glutamate synthase
J6320_10255	COG0069	glutamate synthase activity
J6320_10255	COG0067	glutamate synthase
J6320_10265	COG0070	glutamate synthase
J6320_10265	COG0067	glutamate synthase
J6320_10265	COG0069	glutamate synthase activity
J6320_10275	COG3706	GGDEF domain
J6320_10275	COG4251	negative regulation of phosphorylation
J6320_10275	COG5001	Diguanylate cyclase
J6320_10275	COG2203	Gaf domain
J6320_10280	COG0784	Response regulator, receiver
J6320_10280	COG5002	protein histidine kinase activity
J6320_10280	COG2198	Histidine kinase
J6320_10290	COG0745	RESPONSE REGULATOR receiver
J6320_10300	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
J6320_10320	COG0083	homoserine kinase activity
J6320_10325	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
J6320_10335	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
J6320_10340	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
J6320_10345	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
J6320_10360	COG1115	amino acid carrier protein
J6320_10365	COG3022	response to hydroperoxide
J6320_10370	COG0513	Belongs to the DEAD box helicase family
J6320_10375	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
J6320_10385	COG0716	FMN binding
J6320_10390	COG4974	Belongs to the 'phage' integrase family
J6320_10395	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
J6320_10400	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
J6320_10415	COG2204	response regulator
J6320_10425	COG0667	Aldo Keto reductase
J6320_10450	COG0730	response to heat
J6320_10455	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
J6320_10460	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
J6320_10470	COG1283	sodium-dependent phosphate transmembrane transporter activity
J6320_10475	COG0583	DNA-binding transcription factor activity
J6320_10480	COG0640	Transcriptional regulator
J6320_10485	COG0268	Binds directly to 16S ribosomal RNA
J6320_10490	COG0728	peptidoglycan biosynthetic process
J6320_10495	COG0196	riboflavin kinase activity
J6320_10510	COG1047	Peptidyl-prolyl cis-trans
J6320_10515	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
J6320_10525	COG3279	Response regulator of the LytR AlgR family
J6320_10530	COG3275	phosphorelay sensor kinase activity
J6320_10535	COG1966	Carbon starvation protein
J6320_10555	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
J6320_10560	COG1472	Belongs to the glycosyl hydrolase 3 family
J6320_10565	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
J6320_10570	COG0287	Prephenate dehydrogenase
J6320_10570	COG1605	Chorismate mutase
J6320_10575	COG0739	heme binding
J6320_10585	COG0488	(ABC) transporter
J6320_10595	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
J6320_10600	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
J6320_10605	COG0077	Prephenate dehydratase
J6320_10605	COG1605	Chorismate mutase
J6320_10610	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
J6320_10620	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
J6320_10625	COG0564	pseudouridine synthase activity
J6320_10635	COG0542	response to heat
J6320_10690	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
J6320_10695	COG0826	peptidase U32
J6320_10700	COG2974	May be involved in recombination
J6320_10705	COG0745	RESPONSE REGULATOR receiver
J6320_10710	COG5002	protein histidine kinase activity
J6320_10720	COG0248	Ppx GppA phosphatase
J6320_10725	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
J6320_10730	COG0573	inorganic phosphate transmembrane transporter activity
J6320_10735	COG0581	inorganic phosphate transmembrane transporter activity
J6320_10740	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
J6320_10745	COG0704	Plays a role in the regulation of phosphate uptake
J6320_10755	COG3142	Participates in the control of copper homeostasis
J6320_10760	COG0450	alkyl hydroperoxide reductase
J6320_10765	COG0583	DNA-binding transcription factor activity
J6320_10770	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
J6320_10780	COG0517	IMP dehydrogenase activity
J6320_10790	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
J6320_10800	COG1862	Preprotein translocase
J6320_10805	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
J6320_10810	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
J6320_10825	COG0483	inositol monophosphate 1-phosphatase activity
J6320_10830	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
J6320_10840	COG1104	cysteine desulfurase activity
J6320_10845	COG0822	iron-sulfur transferase activity
J6320_10860	COG0443	Heat shock 70 kDa protein
J6320_10865	COG0633	Ferredoxin
J6320_10870	COG2975	iron-sulfur cluster assembly
J6320_10880	COG0105	UTP biosynthetic process
J6320_10895	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
J6320_10900	COG0124	histidyl-tRNA synthetase
J6320_10905	COG2976	Protein conserved in bacteria
J6320_10910	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
J6320_10915	COG1160	GTP binding
J6320_10935	COG0516	GMP reductase activity
J6320_10935	COG0517	IMP dehydrogenase activity
J6320_10945	COG1757	Na H antiporter
J6320_10955	COG1584	GPR1 FUN34 yaaH family protein
J6320_10960	COG1115	amino acid carrier protein
J6320_10975	COG2873	o-acetylhomoserine
J6320_10980	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
J6320_11000	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
J6320_11000	COG3153	acetyltransferase
J6320_11005	COG0583	DNA-binding transcription factor activity
J6320_11020	COG1396	sequence-specific DNA binding
J6320_11100	COG0732	type I restriction modification DNA specificity domain
J6320_11150	COG0582	viral genome integration into host DNA
J6320_11160	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
J6320_11165	COG2867	negative regulation of translational initiation
J6320_11170	COG2914	Belongs to the UPF0125 (RnfH) family
J6320_11175	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
J6320_11185	COG0497	DNA recombination
J6320_11195	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
J6320_11200	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
J6320_11205	COG1301	dicarboxylic acid transport
J6320_11215	COG0484	heat shock protein binding
J6320_11245	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
J6320_11255	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
J6320_11260	COG0047	phosphoribosylformylglycinamidine synthase activity
J6320_11260	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
J6320_11290	COG2195	Cleaves the N-terminal amino acid of tripeptides
J6320_11295	COG2252	PERMEase
J6320_11300	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
J6320_11305	COG1073	alpha beta
J6320_11315	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
J6320_11320	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
J6320_11325	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
J6320_11330	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
J6320_11330	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
J6320_11345	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
J6320_11355	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
J6320_11360	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
J6320_11370	COG0142	geranyltranstransferase activity
J6320_11375	COG1722	exodeoxyribonuclease VII activity
J6320_11380	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
J6320_11390	COG0301	tRNA thio-modification
J6320_11390	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
J6320_11395	COG0583	DNA-binding transcription factor activity
J6320_11405	COG2363	Small membrane protein
J6320_11415	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
J6320_11420	COG1611	Belongs to the LOG family
J6320_11435	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
J6320_11435	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
J6320_11445	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
J6320_11450	COG1464	Belongs to the NlpA lipoprotein family
J6320_11455	COG2011	ABC-type metal ion transport system permease component
J6320_11460	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
J6320_11465	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
J6320_11475	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J6320_11475	COG1263	PTS System
J6320_11480	COG0366	Alpha amylase catalytic
J6320_11495	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
J6320_11500	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
J6320_11505	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
J6320_11510	COG0321	lipoyl(octanoyl) transferase activity
J6320_11520	COG1686	Belongs to the peptidase S11 family
J6320_11525	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
J6320_11530	COG0772	Belongs to the SEDS family
J6320_11535	COG0768	penicillin binding
J6320_11540	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
J6320_11545	COG0799	negative regulation of ribosome biogenesis
J6320_11550	COG1466	dna polymerase III delta subunit
J6320_11555	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
J6320_11560	COG0495	leucyl-tRNA aminoacylation
J6320_11565	COG2888	peptidyl-tyrosine sulfation
J6320_11570	COG0815	Transfers the fatty acyl group on membrane lipoproteins
J6320_11575	COG4535	Mg2 and Co2 transporter CorC
J6320_11580	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
J6320_11585	COG1702	phosphate starvation-inducible protein PhoH
J6320_11590	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
J6320_11595	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
J6320_11695	COG0012	GTP binding
J6320_11700	COG0193	aminoacyl-tRNA hydrolase activity
J6320_11705	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
J6320_11710	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
J6320_11715	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
J6320_11720	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
J6320_11730	COG2890	protein-(glutamine-N5) methyltransferase activity
J6320_11735	COG3094	Invasion gene expression up-regulator, SirB
J6320_11740	COG2912	Transglutaminase-like superfamily
J6320_11745	COG2877	3-deoxy-8-phosphooctulonate synthase activity
J6320_11750	COG0737	Belongs to the 5'-nucleotidase family
J6320_11755	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
J6320_11760	COG1187	pseudouridine synthase activity
J6320_11765	COG2840	Smr protein MutS2
J6320_11805	COG2217	Heavy metal translocating P-type atpase
J6320_11805	COG2608	mercury ion transmembrane transporter activity
J6320_11815	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
J6320_11870	COG0835	chemotaxis
J6320_11870	COG0784	Response regulator, receiver
J6320_11875	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
J6320_11880	COG1815	bacterial-type flagellum-dependent cell motility
J6320_11885	COG1558	bacterial-type flagellum-dependent cell motility
J6320_11895	COG1749	Flagellar hook protein flgE
J6320_11900	COG4787	bacterial-type flagellum-dependent cell motility
J6320_11910	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
J6320_11915	COG1706	bacterial-type flagellum-dependent cell motility
J6320_11920	COG1705	Flagellar rod assembly protein muramidase FlgJ
J6320_11920	COG3951	Flagellar rod assembly protein muramidase FlgJ
J6320_11930	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
J6320_11935	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
J6320_11940	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
J6320_11945	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
J6320_11950	COG2190	(PTS) system
J6320_11955	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
J6320_11960	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
J6320_11965	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
J6320_11970	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
J6320_11975	COG3115	cell septum assembly
J6320_11980	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
J6320_12000	COG0330	HflC and HflK could
J6320_12005	COG2194	sulfuric ester hydrolase activity
J6320_12030	COG1215	transferase activity, transferring glycosyl groups
J6320_12035	COG1215	transferase activity, transferring glycosyl groups
J6320_12040	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
J6320_12050	COG3118	belongs to the thioredoxin family
J6320_12055	COG0300	oxidoreductase activity
J6320_12060	COG1090	epimerase
J6320_12085	COG0622	Phosphoesterase
J6320_12105	COG3710	Transcriptional regulator
J6320_12110	COG0326	Molecular chaperone. Has ATPase activity
J6320_12120	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
J6320_12125	COG3104	oligopeptide transport
J6320_12130	COG0250	Participates in transcription elongation, termination and antitermination
J6320_12135	COG0367	asparagine synthase
J6320_12145	COG1846	Transcriptional regulator
J6320_12145	COG1940	carbohydrate kinase activity
J6320_12150	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
J6320_12155	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J6320_12155	COG2190	(PTS) system
J6320_12155	COG1263	PTS System
J6320_12160	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
J6320_12165	COG0735	belongs to the Fur family
J6320_12175	COG0716	FMN binding
J6320_12185	COG0596	Alpha beta hydrolase
J6320_12190	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
J6320_12195	COG0033	Phosphoglucomutase
J6320_12205	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
J6320_12220	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
J6320_12225	COG1053	succinate dehydrogenase
J6320_12230	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
J6320_12235	COG0567	Dehydrogenase, E1 component
J6320_12240	COG0508	dehydrogenase complex catalyzes the overall conversion of
J6320_12245	COG0045	succinate-CoA ligase (ADP-forming) activity
J6320_12255	COG1108	ABC-type Mn2 Zn2 transport systems permease components
J6320_12260	COG1121	(ABC) transporter
J6320_12265	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
J6320_12270	COG4977	sequence-specific DNA binding
J6320_12275	COG1918	ferrous iron import across plasma membrane
J6320_12300	COG0018	arginyl-trna synthetase
J6320_12305	COG3102	Protein conserved in bacteria
J6320_12310	COG0788	formyltetrahydrofolate deformylase activity
J6320_12315	COG1199	ATP-dependent helicase activity
J6320_12320	COG1214	PFAM Peptidase M22, glycoprotease
J6320_12330	COG3065	identical protein binding
J6320_12335	COG2267	carboxylic ester hydrolase activity
J6320_12340	COG0318	PFAM AMP-dependent synthetase and ligase
J6320_12345	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
J6320_12350	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
J6320_12355	COG2894	cell division
J6320_12360	COG0850	regulation of cytokinetic process
J6320_12365	COG3100	YcgL domain-containing protein
J6320_12370	COG2951	lytic endotransglycosylase activity
J6320_12380	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
J6320_12385	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
J6320_12400	COG1028	Short-chain dehydrogenase reductase Sdr
J6320_12410	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
J6320_12435	COG2986	histidine ammonia-lyase
J6320_12440	COG1216	Glycosyl transferase, family 2
J6320_12445	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
J6320_12460	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
J6320_12465	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
J6320_12500	COG0513	Belongs to the DEAD box helicase family
J6320_12505	COG0569	domain protein
J6320_12510	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
J6320_12525	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
J6320_12530	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
J6320_12535	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
J6320_12540	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
J6320_12555	COG0544	peptidyl-prolyl cis-trans isomerase activity
J6320_12565	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
J6320_12570	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
J6320_12575	COG0776	regulation of translation
J6320_12580	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
J6320_12585	COG1555	photosystem II stabilization
J6320_12600	COG0232	Belongs to the dGTPase family. Type 2 subfamily
J6320_12605	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
J6320_12610	COG0436	Aminotransferase
J6320_12615	COG1169	isochorismate synthase
J6320_12620	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
J6320_12630	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
J6320_12650	COG2855	membrane
J6320_12655	COG0477	Major facilitator Superfamily
J6320_12705	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
J6320_12725	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
J6320_12730	COG1522	sequence-specific DNA binding
J6320_12740	COG1946	Acyl-CoA thioesterase
J6320_12745	COG3126	Type III secretion system lipoprotein chaperone (YscW)
J6320_12770	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
J6320_12775	COG0516	GMP reductase activity
J6320_12775	COG0517	IMP dehydrogenase activity
J6320_12800	COG0537	adenosine 5'-monophosphoramidase activity
J6320_12825	COG3150	esterase
J6320_12830	COG1252	NADH dehydrogenase
J6320_12855	COG4591	ABC-type transport system involved in lipoprotein release permease component
J6320_12860	COG1136	(ABC) transporter
J6320_12865	COG4591	ABC-type transport system involved in lipoprotein release permease component
J6320_12875	COG0658	competence protein
J6320_12875	COG2333	competence protein COMEC
J6320_12880	COG1132	(ABC) transporter
J6320_12900	COG2719	SpoVR family
J6320_12905	COG2718	Belongs to the UPF0229 family
J6320_12910	COG2766	serine protein kinase
J6320_12915	COG3013	Belongs to the UPF0304 family
J6320_12925	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
J6320_12935	COG1882	Formate acetyltransferase
J6320_12975	COG0708	Exodeoxyribonuclease III
J6320_12985	COG3923	Primosomal replication protein n
J6320_12990	COG0730	response to heat
J6320_12995	COG1199	ATP-dependent helicase activity
J6320_13000	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
J6320_13005	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
J6320_13010	COG1187	pseudouridine synthase activity
J6320_13020	COG1278	Cold shock
J6320_13025	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
J6320_13030	COG0542	response to heat
J6320_13035	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
J6320_13040	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
J6320_13045	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
J6320_13065	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
J6320_13070	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
J6320_13075	COG0297	glycogen (starch) synthase activity
J6320_13095	COG3070	regulator of competence-specific genes
J6320_13100	COG1609	Transcriptional regulator
J6320_13105	COG3381	protein complex oligomerization
J6320_13110	COG0745	RESPONSE REGULATOR receiver
J6320_13120	COG1434	Gram-negative-bacterium-type cell wall biogenesis
J6320_13125	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
J6320_13130	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
J6320_13135	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
J6320_13140	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
J6320_13160	COG0189	ligase activity
J6320_13160	COG4067	protein conserved in archaea
J6320_13165	COG0500	methyltransferase
J6320_13175	COG1801	Protein of unknown function DUF72
J6320_13185	COG0217	transcriptional regulatory protein
J6320_13190	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
J6320_13195	COG0632	four-way junction helicase activity
J6320_13200	COG2255	four-way junction helicase activity
J6320_13205	COG1271	oxidase subunit
J6320_13210	COG1294	oxidase, subunit
J6320_13215	COG4890	Cyd operon protein YbgT
J6320_13225	COG0824	Thioesterase
J6320_13230	COG0811	peptide transport
J6320_13245	COG0823	Involved in the tonB-independent uptake of proteins
J6320_13250	COG2885	chlorophyll binding
J6320_13255	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
J6320_13260	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
J6320_13270	COG3766	membrane
J6320_13280	COG0754	glutathionylspermidine amidase activity
J6320_13290	COG0784	Response regulator, receiver
J6320_13290	COG5002	protein histidine kinase activity
J6320_13305	COG1294	oxidase, subunit
J6320_13310	COG1271	oxidase subunit
J6320_13330	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J6320_13335	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
J6320_13360	COG3568	Endonuclease Exonuclease Phosphatase
J6320_13385	COG0583	DNA-binding transcription factor activity
J6320_13395	COG0686	Belongs to the AlaDH PNT family
J6320_13405	COG1674	ftsk spoiiie
J6320_13415	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
J6320_13435	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
J6320_13460	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
J6320_13480	COG0300	oxidoreductase activity
J6320_13495	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
J6320_13505	COG2268	Band 7 protein
J6320_13515	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
J6320_13520	COG2915	High frequency lysogenization protein hflD homolog
J6320_13535	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J6320_13545	COG1757	Na H antiporter
J6320_13560	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
J6320_13570	COG0131	Imidazoleglycerol-phosphate dehydratase
J6320_13570	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
J6320_13575	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
J6320_13580	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
J6320_13590	COG0140	phosphoribosyl-ATP diphosphatase activity
J6320_13590	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
J6320_13595	COG3012	SEC-C Motif Domain Protein
J6320_13600	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
J6320_13605	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
J6320_13610	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
J6320_13615	COG0215	cysteine-tRNA ligase activity
J6320_13620	COG1435	thymidine kinase activity
J6320_13625	COG1434	Gram-negative-bacterium-type cell wall biogenesis
J6320_13650	COG2116	formate transmembrane transporter activity
J6320_13660	COG0390	transport system, permease component
J6320_13665	COG4459	periplasmic nitrate reductase
J6320_13670	COG3005	denitrification pathway
J6320_13675	COG0243	molybdopterin cofactor binding
J6320_13690	COG1227	inorganic diphosphatase activity
J6320_13700	COG4172	Belongs to the ABC transporter superfamily
J6320_13710	COG4171	peptide transport system, permease
J6320_13725	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
J6320_13730	COG1842	Phage shock protein A
J6320_13740	COG1983	PspC domain protein
J6320_13760	COG2818	Glycosylase
J6320_13765	COG5380	lipid catabolic process
J6320_13770	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
J6320_13775	COG0626	cystathionine gamma-synthase activity
J6320_13785	COG0733	neurotransmitter:sodium symporter activity
J6320_13790	COG0564	pseudouridine synthase activity
J6320_13800	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
J6320_13805	COG1151	hydroxylamine reductase activity
J6320_13810	COG3604	Transcriptional regulator
J6320_13820	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
J6320_13825	COG4136	ATPase activity
J6320_13830	COG4135	transport system, permease component
J6320_13835	COG4134	Bacterial extracellular solute-binding protein
J6320_13845	COG3313	Fe-S protein
J6320_13865	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
J6320_13885	COG1061	Type III restriction enzyme res subunit
J6320_13890	COG1187	pseudouridine synthase activity
J6320_13895	COG2814	Major facilitator Superfamily
J6320_13905	COG0702	epimerase
J6320_13910	COG0534	Mate efflux family protein
J6320_13930	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
J6320_13940	COG1960	acyl-CoA dehydrogenase activity
J6320_13945	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
J6320_13950	COG2985	domain, Protein
J6320_13950	COG3273	potassium ion transport
J6320_13955	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
J6320_13965	COG1737	Transcriptional regulator
J6320_13970	COG0076	glutamate decarboxylase activity
J6320_13980	COG2431	L-lysine efflux transmembrane transporter activity
J6320_13990	COG3070	regulator of competence-specific genes
J6320_14005	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J6320_14005	COG4191	Histidine kinase
J6320_14015	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
J6320_14020	COG3048	D-serine ammonia-lyase activity
J6320_14025	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
J6320_14030	COG4988	ABC transporter
J6320_14035	COG0492	ferredoxin-NADP+ reductase activity
J6320_14060	COG0471	metal ion transport
J6320_14065	COG2949	membrane
J6320_14070	COG0281	malic enzyme
J6320_14075	COG1643	Atp-dependent helicase
J6320_14090	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
J6320_14125	COG0247	lactate metabolic process
J6320_14125	COG0277	FAD linked oxidase domain protein
J6320_14140	COG2986	histidine ammonia-lyase
J6320_14145	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
J6320_14150	COG0010	Belongs to the arginase family
J6320_14155	COG1228	amidohydrolase
J6320_14160	COG2188	Transcriptional regulator
J6320_14175	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
J6320_14185	COG0291	Belongs to the bacterial ribosomal protein bL35 family
J6320_14195	COG0393	Putative heavy-metal-binding
J6320_14230	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
J6320_14235	COG0072	phenylalanine-tRNA ligase activity
J6320_14235	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
J6320_14245	COG0776	regulation of translation
J6320_14255	COG0500	methyltransferase
J6320_14260	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
J6320_14265	COG0295	cytidine deaminase activity
J6320_14270	COG1346	cytolysis
J6320_14275	COG1380	Effector of murein hydrolase LrgA
J6320_14280	COG2925	Exonuclease
J6320_14285	COG1823	symporter activity
J6320_14295	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
J6320_14300	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
J6320_14320	COG2988	succinylglutamate desuccinylase activity
J6320_14325	COG4139	cobalamin transport
J6320_14330	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
J6320_14350	COG0583	DNA-binding transcription factor activity
J6320_14360	COG1451	nucleotide metabolic process
J6320_14395	COG3938	Belongs to the proline racemase family
J6320_14410	COG2423	ornithine cyclodeaminase activity
J6320_14415	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
J6320_14420	COG3842	ATPase activity
J6320_14425	COG1176	ABC-type spermidine putrescine transport system, permease component I
J6320_14430	COG1177	transmembrane transport
J6320_14465	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J6320_14470	COG0601	transmembrane transport
J6320_14480	COG2195	Cleaves the N-terminal amino acid of tripeptides
J6320_14490	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
J6320_14500	COG0625	glutathione transferase activity
J6320_14575	COG1742	UPF0060 membrane protein
J6320_14590	COG1757	Na H antiporter
J6320_14595	COG0174	glutamine synthetase
J6320_14600	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
J6320_14605	COG1396	sequence-specific DNA binding
J6320_14605	COG1917	Cupin 2, conserved barrel domain protein
J6320_14610	COG1012	belongs to the aldehyde dehydrogenase family
J6320_14615	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
J6320_14625	COG2957	Belongs to the agmatine deiminase family
J6320_14630	COG1012	belongs to the aldehyde dehydrogenase family
J6320_14635	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
J6320_14640	COG2200	EAL domain
J6320_14650	COG1846	Transcriptional regulator
J6320_14655	COG2315	Protein conserved in bacteria
J6320_14695	COG3063	Type IV pilus biogenesis stability protein PilW
J6320_14700	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
J6320_14715	COG1560	Kdo2-lipid A biosynthetic process
J6320_14720	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
J6320_14725	COG1280	lysine exporter protein (LysE YggA)
J6320_14735	COG1115	amino acid carrier protein
J6320_14760	COG1368	sulfuric ester hydrolase activity
J6320_14765	COG2113	Glycine betaine
J6320_14770	COG4176	ABC-type proline glycine betaine transport system permease component
J6320_14775	COG4175	Glycine betaine
J6320_14790	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
J6320_14795	COG0456	acetyltransferase
J6320_14800	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
J6320_14805	COG0662	Cupin 2, conserved barrel domain protein
J6320_14810	COG0527	aspartate kinase activity
J6320_14815	COG3119	arylsulfatase activity
J6320_14830	COG0641	radical SAM
J6320_14845	COG3119	arylsulfatase activity
J6320_14870	COG1538	Outer membrane efflux protein
J6320_14885	COG1349	DNA-binding transcription factor activity
J6320_14890	COG0673	inositol 2-dehydrogenase activity
J6320_14895	COG4702	Belongs to the UPF0303 family
J6320_14920	COG0471	metal ion transport
J6320_14935	COG3300	MHYT domain
J6320_14935	COG5001	Diguanylate cyclase
J6320_14950	COG1328	CTP reductase activity
J6320_14955	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
J6320_14965	COG0861	Integral membrane protein TerC family
J6320_14975	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
J6320_14985	COG0814	amino acid
J6320_15000	COG1120	ATPase activity
J6320_15005	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
J6320_15015	COG4774	siderophore transport
J6320_15025	COG1132	(ABC) transporter
J6320_15030	COG1132	(ABC) transporter
J6320_15045	COG0583	DNA-binding transcription factor activity
J6320_15070	COG0443	Heat shock 70 kDa protein
J6320_15075	COG0443	Heat shock 70 kDa protein
J6320_15120	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
J6320_15125	COG1643	Atp-dependent helicase
J6320_15140	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
J6320_15150	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
J6320_15155	COG1215	transferase activity, transferring glycosyl groups
J6320_15160	COG0438	transferase activity, transferring glycosyl groups
J6320_15190	COG0438	transferase activity, transferring glycosyl groups
J6320_15195	COG0438	transferase activity, transferring glycosyl groups
J6320_15200	COG2204	response regulator
J6320_15230	COG1793	dna ligase
J6320_15240	COG0534	Mate efflux family protein
J6320_15245	COG0307	riboflavin synthase, alpha
J6320_15255	COG3001	Fructosamine kinase
J6320_15265	COG3706	GGDEF domain
J6320_15275	COG0791	NLP P60 protein
J6320_15310	COG3148	PFAM DTW domain containing protein
J6320_15315	COG1940	carbohydrate kinase activity
J6320_15325	COG0303	'Molybdopterin
J6320_15330	COG0746	molybdenum cofactor guanylyltransferase activity
J6320_15335	COG3842	ATPase activity
J6320_15350	COG2204	response regulator
J6320_15355	COG4191	Histidine kinase
J6320_15365	COG0488	(ABC) transporter
J6320_15390	COG3381	protein complex oligomerization
J6320_15400	COG0243	molybdopterin cofactor binding
J6320_15400	COG3383	formate dehydrogenase (NAD+) activity
J6320_15405	COG0437	4 iron, 4 sulfur cluster binding
J6320_15430	COG0004	ammonium transporteR
J6320_15440	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
J6320_15445	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
J6320_15455	COG1177	transmembrane transport
J6320_15465	COG3842	ATPase activity
J6320_15490	COG0589	response to stress
J6320_15495	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
J6320_15510	COG2217	Heavy metal translocating P-type atpase
J6320_15520	COG2010	Cytochrome c
J6320_15535	COG3278	Belongs to the heme-copper respiratory oxidase family
J6320_15550	COG0784	Response regulator, receiver
J6320_15550	COG2205	protein histidine kinase activity
J6320_15565	COG3120	sequence-specific DNA binding
J6320_15570	COG1067	ATP-dependent peptidase activity
J6320_15575	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
J6320_15590	COG0488	(ABC) transporter
J6320_15600	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
J6320_15600	COG0116	Belongs to the methyltransferase superfamily
J6320_15610	COG0167	dihydroorotate dehydrogenase activity
J6320_15615	COG2902	Dehydrogenase
J6320_15625	COG0308	aminopeptidase N
J6320_15640	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
J6320_15645	COG1956	GAF domain-containing protein
J6320_15650	COG1132	(ABC) transporter
J6320_15655	COG2995	paraquat-inducible protein a
J6320_15660	COG3008	intermembrane lipid transfer
J6320_15685	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
J6320_15690	COG1666	GTP binding
J6320_15700	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J6320_15705	COG4597	amino acid ABC transporter
J6320_15710	COG0765	amino acid transport
J6320_15715	COG1126	abc transporter atp-binding protein
J6320_15720	COG0670	Belongs to the BI1 family
J6320_15730	COG2920	part of a sulfur-relay system
J6320_15735	COG1254	Belongs to the acylphosphatase family
J6320_15740	COG0840	transmembrane signaling receptor activity
J6320_15790	COG1414	Transcriptional regulator
J6320_15800	COG0656	L-ascorbic acid biosynthetic process
J6320_15805	COG0583	DNA-binding transcription factor activity
J6320_15815	COG0583	DNA-binding transcription factor activity
J6320_15820	COG2814	Major facilitator Superfamily
J6320_15840	COG1335	isochorismatase
J6320_15845	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J6320_15860	COG1410	methionine synthase
J6320_15860	COG0646	methionine synthase
J6320_15865	COG1126	abc transporter atp-binding protein
J6320_15870	COG0765	amino acid transport
J6320_15875	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J6320_15890	COG0583	DNA-binding transcription factor activity
J6320_15905	COG0583	DNA-binding transcription factor activity
J6320_15910	COG0583	DNA-binding transcription factor activity
J6320_15925	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
J6320_15930	COG0602	queuosine metabolic process
J6320_15935	COG0561	phosphatase activity
J6320_15960	COG2828	Protein conserved in bacteria
J6320_15970	COG0372	Belongs to the citrate synthase family
J6320_15975	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
J6320_16010	COG0730	response to heat
J6320_16015	COG2358	TRAP transporter, solute receptor (TAXI family
J6320_16030	COG0457	Tetratricopeptide repeat
J6320_16100	COG4790	Type iii secretion
J6320_16105	COG4794	Type iii secretion
J6320_16110	COG4791	protein targeting
J6320_16115	COG4792	protein secretion
J6320_16120	COG2207	Transcriptional regulator
J6320_16150	COG3177	Filamentation induced by cAMP protein fic
J6320_16170	COG4669	(LipO)protein
J6320_16245	COG1012	belongs to the aldehyde dehydrogenase family
J6320_16250	COG3284	Transcriptional regulator
J6320_16270	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
J6320_16275	COG0363	glucosamine-6-phosphate deaminase activity
J6320_16280	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
J6320_16285	COG2207	Transcriptional regulator
J6320_16295	COG4565	transcriptional regulatory protein
J6320_16300	COG3290	protein histidine kinase activity
J6320_16315	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J6320_16330	COG0583	DNA-binding transcription factor activity
J6320_16345	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
J6320_16355	COG2985	domain, Protein
J6320_16380	COG2272	Belongs to the type-B carboxylesterase lipase family
J6320_16385	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
J6320_16390	COG0729	surface antigen
J6320_16400	COG1280	lysine exporter protein (LysE YggA)
J6320_16405	COG1280	lysine exporter protein (LysE YggA)
J6320_16410	COG5507	3-demethylubiquinone-9 3-methyltransferase
J6320_16430	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
J6320_16440	COG0110	maltose O-acetyltransferase activity
J6320_16495	COG1280	lysine exporter protein (LysE YggA)
J6320_16610	COG0346	lactoylglutathione lyase activity
J6320_16725	COG2188	Transcriptional regulator
J6320_16730	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
J6320_16730	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J6320_16730	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J6320_16735	COG0383	alpha-mannosidase activity
J6320_16740	COG1929	Belongs to the glycerate kinase type-1 family
J6320_16745	COG1482	cell wall glycoprotein biosynthetic process
J6320_16755	COG1085	galactose-1-phosphate uridylyltransferase
J6320_16760	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
J6320_16765	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
J6320_16775	COG1609	Transcriptional regulator
J6320_16865	COG1196	nuclear chromosome segregation
J6320_16930	COG1403	HNH endonuclease
J6320_17035	COG0346	lactoylglutathione lyase activity
J6320_17300	COG0653	protein targeting
J6320_17370	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
J6320_17380	COG3768	UPF0283 membrane protein
J6320_17385	COG3106	COG3106 Predicted ATPase
J6320_17400	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
J6320_17405	COG0784	Response regulator, receiver
J6320_17405	COG2205	protein histidine kinase activity
J6320_17415	COG0494	nUDIX hydrolase
J6320_17420	COG0814	amino acid
J6320_17425	COG1760	l-serine dehydratase
J6320_17430	COG2200	EAL domain
J6320_17440	COG0720	synthase
J6320_17445	COG0840	transmembrane signaling receptor activity
J6320_17450	COG0017	Asparaginyl-tRNA synthetase
J6320_17460	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J6320_17475	COG1448	Aminotransferase
J6320_17495	COG0840	transmembrane signaling receptor activity
J6320_17500	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
J6320_17530	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
J6320_17545	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
J6320_17550	COG3108	Peptidase M15
J6320_17555	COG2989	Protein conserved in bacteria
J6320_17580	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
J6320_17590	COG3088	subunit of a heme lyase
J6320_17590	COG4235	cytochrome complex assembly
J6320_17605	COG3301	Polysulphide reductase, NrfD
J6320_17610	COG0437	4 iron, 4 sulfur cluster binding
J6320_17620	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
J6320_17640	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
J6320_17675	COG0019	diaminopimelate decarboxylase activity
J6320_17715	COG0322	excinuclease ABC activity
J6320_17720	COG2197	response regulator
J6320_17725	COG0417	DNA replication proofreading
J6320_17745	COG1187	pseudouridine synthase activity
J6320_17755	COG0009	L-threonylcarbamoyladenylate synthase
J6320_17760	COG0613	PHP domain protein
J6320_17770	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
J6320_17775	COG0512	Glutamine amidotransferase of anthranilate synthase
J6320_17785	COG0134	indole-3-glycerol-phosphate synthase activity
J6320_17785	COG0135	phosphoribosylanthranilate isomerase activity
J6320_17795	COG0159	tryptophan synthase activity
J6320_17800	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
J6320_17805	COG0318	PFAM AMP-dependent synthetase and ligase
J6320_17840	COG2350	Protein conserved in bacteria
J6320_17850	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
J6320_17855	COG0583	DNA-binding transcription factor activity
J6320_17870	COG5001	Diguanylate cyclase
J6320_17875	COG1032	radical SAM domain protein
J6320_17895	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
J6320_17900	COG0463	Glycosyl transferase, family 2
J6320_17905	COG0745	RESPONSE REGULATOR receiver
J6320_17910	COG3850	Histidine kinase
J6320_17910	COG5002	protein histidine kinase activity
J6320_17960	COG0577	efflux transmembrane transporter activity
J6320_17960	COG1136	(ABC) transporter
J6320_17965	COG0577	efflux transmembrane transporter activity
J6320_17965	COG1136	(ABC) transporter
J6320_17970	COG1136	(ABC) transporter
J6320_17970	COG0577	efflux transmembrane transporter activity
J6320_17980	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J6320_18000	COG3118	belongs to the thioredoxin family
J6320_18005	COG4232	protein-disulfide reductase activity
J6320_18040	COG2863	cytochrome
J6320_18045	COG3258	Cytochrome c
J6320_18050	COG2995	paraquat-inducible protein a
J6320_18055	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
J6320_18055	COG3008	intermembrane lipid transfer
J6320_18075	COG4166	transmembrane transport
J6320_18085	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
J6320_18090	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
J6320_18100	COG0539	negative regulation of cytoplasmic translation
J6320_18105	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
J6320_18110	COG0616	signal peptide processing
J6320_18115	COG1028	Short-chain dehydrogenase reductase Sdr
J6320_18130	COG0587	DNA-directed DNA polymerase activity
J6320_18135	COG0784	Response regulator, receiver
J6320_18135	COG0835	chemotaxis
J6320_18140	COG1940	carbohydrate kinase activity
J6320_18145	COG0469	pyruvate kinase activity
J6320_18150	COG4667	esterase of the alpha-beta hydrolase superfamily
J6320_18165	COG0733	neurotransmitter:sodium symporter activity
J6320_18180	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J6320_18180	COG1263	PTS System
J6320_18185	COG0084	hydrolase, TatD family'
J6320_18190	COG0470	DNA polymerase III
J6320_18195	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
J6320_18200	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
J6320_18230	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
J6320_18235	COG0416	fatty acid biosynthetic process
J6320_18245	COG1399	metal-binding, possibly nucleic acid-binding protein
J6320_18250	COG0424	maF-like protein
J6320_18255	COG0564	pseudouridine synthase activity
J6320_18260	COG1530	ribonuclease E activity
J6320_18265	COG0659	secondary active sulfate transmembrane transporter activity
J6320_18270	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
J6320_18275	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
J6320_18285	COG0572	uridine kinase
J6320_18295	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
J6320_18295	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
J6320_18305	COG2186	Transcriptional regulator
J6320_18310	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
J6320_18315	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
J6320_18320	COG3318	Belongs to the UPF0149 family
J6320_18320	COG3012	SEC-C Motif Domain Protein
J6320_18325	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
J6320_18330	COG3706	GGDEF domain
J6320_18335	COG0366	Alpha amylase catalytic
J6320_18340	COG1122	ATPase activity
J6320_18345	COG4120	Belongs to the binding-protein-dependent transport system permease family
J6320_18355	COG3092	negative regulation of chromosome organization
J6320_18360	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
J6320_18365	COG0280	phosphate acetyltransferase
J6320_18365	COG0857	belongs to the CobB CobQ family
J6320_18375	COG0435	Glutathione S-transferase
J6320_18385	COG0444	Belongs to the ABC transporter superfamily
J6320_18390	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J6320_18395	COG0601	transmembrane transport
J6320_18405	COG0314	molybdopterin synthase activity
J6320_18410	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
J6320_18415	COG0315	cyclic pyranopterin monophosphate synthase activity
J6320_18420	COG0521	Mo-molybdopterin cofactor biosynthetic process
J6320_18425	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
J6320_18430	COG0391	Required for morphogenesis under gluconeogenic growth conditions
J6320_18435	COG2198	Histidine kinase
J6320_18440	COG2204	response regulator
J6320_18445	COG0556	nucleotide-excision repair
J6320_18455	COG1882	Formate acetyltransferase
J6320_18460	COG4657	Part of a membrane complex involved in electron transport
J6320_18465	COG2878	Part of a membrane complex involved in electron transport
J6320_18470	COG4656	Part of a membrane complex involved in electron transport
J6320_18475	COG4658	electron transport chain
J6320_18480	COG4659	FMN binding
J6320_18485	COG4660	Part of a membrane complex involved in electron transport
J6320_18490	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
J6320_18495	COG0346	lactoylglutathione lyase activity
J6320_18505	COG2885	chlorophyll binding
J6320_18510	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
J6320_18515	COG2056	Na+-H+ antiporter family
J6320_18525	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
J6320_18545	COG1012	belongs to the aldehyde dehydrogenase family
J6320_18545	COG1454	alcohol dehydrogenase
J6320_18550	COG2095	MarC family integral membrane protein
J6320_18555	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
J6320_18560	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
J6320_18580	COG3081	Nucleoid-associated protein
J6320_18585	COG3082	Protein of unknown function (DUF1414)
J6320_18600	COG0123	including yeast histone deacetylase and acetoin utilization protein
J6320_18615	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
J6320_18620	COG0778	Nitroreductase
J6320_18635	COG0446	pyridine nucleotide-disulphide oxidoreductase
J6320_18635	COG1902	pentaerythritol trinitrate reductase activity
J6320_18640	COG0616	signal peptide processing
J6320_18645	COG0252	asparaginase activity
J6320_18650	COG3139	Protein of unknown function (DUF1315)
J6320_18660	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
J6320_18665	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
J6320_18680	COG2226	methyltransferase
J6320_18695	COG1785	Belongs to the alkaline phosphatase family
J6320_18705	COG0346	lactoylglutathione lyase activity
J6320_18710	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
J6320_18715	COG0668	transmembrane transport
J6320_18720	COG2983	Belongs to the UPF0260 family
J6320_18725	COG2261	transglycosylase associated protein
J6320_18735	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
J6320_18740	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
J6320_18755	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
J6320_18760	COG2832	Protein of unknown function (DUF454)
J6320_18765	COG0745	RESPONSE REGULATOR receiver
J6320_18770	COG0583	DNA-binding transcription factor activity
J6320_18775	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
J6320_18780	COG1286	toxin biosynthetic process
J6320_18785	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
J6320_18790	COG0285	dihydrofolate synthase activity
J6320_18795	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
J6320_18800	COG0101	tRNA pseudouridine synthase activity
J6320_18810	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
J6320_18815	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
J6320_18820	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
J6320_18825	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
J6320_18825	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
J6320_18830	COG0431	NADPH-dependent FMN reductase
J6320_18840	COG3101	peptidyl-lysine hydroxylation
J6320_18845	COG2860	membrane
J6320_18850	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
J6320_18855	COG2890	protein-(glutamine-N5) methyltransferase activity
J6320_18860	COG2840	Smr protein MutS2
J6320_18865	COG2062	phosphohistidine phosphatase, SixA
J6320_18880	COG1024	Enoyl-CoA hydratase
J6320_18880	COG1250	3-hydroxyacyl-CoA dehydrogenase
J6320_18885	COG0183	Belongs to the thiolase family
J6320_18905	COG2067	long-chain fatty acid transport protein
J6320_18920	COG3088	subunit of a heme lyase
J6320_18920	COG4235	cytochrome complex assembly
J6320_18930	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
J6320_18935	COG1138	Cytochrome C-type biogenesis protein
J6320_18940	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
J6320_18945	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
J6320_18950	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
J6320_18955	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
J6320_18960	COG4133	protoheme IX ABC transporter activity
J6320_18970	COG0835	chemotaxis
J6320_18980	COG1192	Involved in chromosome partitioning
J6320_18985	COG2201	protein-glutamate methylesterase activity
J6320_18990	COG2198	Histidine kinase
J6320_18990	COG0784	Response regulator, receiver
J6320_18990	COG0643	Histidine kinase
J6320_18995	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
J6320_19035	COG1987	bacterial-type flagellum assembly
J6320_19090	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
J6320_19100	COG1677	Flagellar hook-basal body complex protein FliE
J6320_19120	COG1516	flagellar protein fliS
J6320_19130	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
J6320_19135	COG1334	flagellar protein FlaG
J6320_19140	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
J6320_19145	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
J6320_19150	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
J6320_19160	COG2837	iron assimilation
J6320_19185	COG1393	Belongs to the ArsC family
J6320_19190	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
J6320_19205	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
J6320_19210	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
J6320_19220	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
J6320_19235	COG4783	chaperone-mediated protein folding
J6320_19240	COG1393	Belongs to the ArsC family
J6320_19260	COG2233	PERMEase
J6320_19265	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
J6320_19270	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
J6320_19275	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
J6320_19280	COG0121	glutamine amidotransferase
J6320_19285	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
J6320_19290	COG1960	acyl-CoA dehydrogenase activity
J6320_19325	COG0328	RNA-DNA hybrid ribonuclease activity
J6320_19330	COG2226	methyltransferase
J6320_19335	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
J6320_19340	COG0741	lytic transglycosylase activity
J6320_19340	COG1388	LysM domain
J6320_19350	COG3021	interspecies interaction between organisms
J6320_19355	COG0347	Belongs to the P(II) protein family
J6320_19370	COG0825	malonyl-CoA metabolic process
J6320_19375	COG0587	DNA-directed DNA polymerase activity
J6320_19385	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
J6320_19390	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
J6320_19400	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
J6320_19405	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
J6320_19415	COG0750	zinc metalloprotease
J6320_19420	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
J6320_19425	COG0575	Belongs to the CDS family
J6320_19430	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
J6320_19435	COG0233	cytoplasmic translational termination
J6320_19440	COG0528	UMP kinase activity
J6320_19445	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
J6320_19450	COG0052	Belongs to the universal ribosomal protein uS2 family
J6320_19455	COG0024	Methionine aminopeptidase
J6320_19460	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
J6320_19470	COG0564	pseudouridine synthase activity
J6320_19505	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
J6320_19510	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
J6320_19535	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
J6320_19545	COG0254	rRNA binding
J6320_19550	COG1720	tRNA m6t6A37 methyltransferase activity
J6320_19555	COG0442	prolyl-tRNA aminoacylation
J6320_19575	COG0733	neurotransmitter:sodium symporter activity
J6320_19595	COG0514	ATP-dependent DNA helicase (RecQ)
J6320_19600	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
J6320_19620	COG1477	protein flavinylation
J6320_19625	COG2871	sodium ion transport
J6320_19630	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
J6320_19635	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
J6320_19640	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
J6320_19645	COG1805	sodium ion transport
J6320_19650	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
J6320_19655	COG0271	Belongs to the BolA IbaG family
J6320_19660	COG2813	Specifically methylates the guanine in position
J6320_19665	COG3056	Lipoprotein
J6320_19685	COG1595	DNA-templated transcription, initiation
J6320_19700	COG3248	Nucleoside-binding outer membrane protein
J6320_19705	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
J6320_19710	COG0693	protein deglycase activity
J6320_19715	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
J6320_19720	COG3706	GGDEF domain
J6320_19725	COG2166	iron-sulfur cluster assembly
J6320_19730	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
J6320_19735	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
J6320_19745	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
J6320_19745	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
J6320_19755	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
J6320_19760	COG1074	ATP-dependent DNA helicase activity
J6320_19765	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
J6320_19785	COG3141	response to X-ray
J6320_19800	COG2171	N-acyltransferase activity
J6320_19805	COG0584	glycerophosphoryl diester phosphodiesterase
J6320_19810	COG2271	Major facilitator Superfamily
J6320_19815	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
J6320_19820	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
J6320_19825	COG1349	DNA-binding transcription factor activity
J6320_19830	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
J6320_19835	COG0598	Magnesium transport protein CorA
J6320_19855	COG1609	Transcriptional regulator
J6320_19860	COG0583	DNA-binding transcription factor activity
J6320_19920	COG4964	Belongs to the GSP D family
J6320_19945	COG2169	Transcriptional regulator
J6320_19950	COG1022	Amp-dependent synthetase and ligase
J6320_19960	COG0583	DNA-binding transcription factor activity
J6320_19965	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
J6320_19970	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
J6320_19980	COG0560	Phosphoserine phosphatase
J6320_19990	COG0813	purine-nucleoside phosphorylase activity
J6320_19995	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
J6320_20000	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
J6320_20005	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
J6320_20010	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
J6320_20015	COG0084	hydrolase, TatD family'
J6320_20045	COG3153	acetyltransferase
J6320_20050	COG3154	lipid carrier protein
J6320_20060	COG0826	peptidase U32
J6320_20065	COG0826	peptidase U32
J6320_20085	COG1185	polyribonucleotide nucleotidyltransferase activity
J6320_20090	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
J6320_20095	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
J6320_20100	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
J6320_20105	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
J6320_20110	COG0195	Participates in both transcription termination and antitermination
J6320_20115	COG0779	Required for maturation of 30S ribosomal subunits
J6320_20130	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
J6320_20135	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
J6320_20140	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
J6320_20145	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
J6320_20150	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
J6320_20155	COG1534	Rna-binding protein
J6320_20160	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
J6320_20165	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
J6320_20170	COG2027	D-alanyl-D-alanine carboxypeptidase
J6320_20180	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
J6320_20185	COG0739	heme binding
J6320_20210	COG0628	permease
J6320_20220	COG2205	protein histidine kinase activity
J6320_20220	COG0784	Response regulator, receiver
J6320_20225	COG0747	negative chemotaxis
J6320_20235	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J6320_20240	COG0444	Belongs to the ABC transporter superfamily
J6320_20245	COG4608	Belongs to the ABC transporter superfamily
J6320_20255	COG2971	BadF BadG BcrA BcrD
J6320_20270	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
J6320_20275	COG3842	ATPase activity
J6320_20285	COG1840	ABC-type Fe3 transport system, periplasmic component
J6320_20290	COG0004	ammonium transporteR
J6320_20300	COG3112	Uncharacterised protein family (UPF0231)
J6320_20305	COG1049	propionate catabolic process, 2-methylcitrate cycle
J6320_20310	COG1752	Esterase of the alpha-beta hydrolase superfamily
J6320_20315	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
J6320_20320	COG1643	Atp-dependent helicase
J6320_20325	COG1489	DNA binding
J6320_20335	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
J6320_20345	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
J6320_20350	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
J6320_20355	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
J6320_20360	COG1560	Kdo2-lipid A biosynthetic process
J6320_20365	COG0842	Transport permease protein
J6320_20370	COG1131	(ABC) transporter
J6320_20375	COG0659	secondary active sulfate transmembrane transporter activity
J6320_20380	COG0288	reversible hydration of carbon dioxide
J6320_20395	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
J6320_20400	COG0508	dehydrogenase complex catalyzes the overall conversion of
J6320_20405	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
J6320_20410	COG2186	Transcriptional regulator
J6320_20420	COG0157	Belongs to the NadC ModD family
J6320_20430	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
J6320_20435	COG1459	type II secretion system
J6320_20445	COG0237	dephospho-CoA kinase activity
J6320_20450	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
J6320_20455	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
J6320_20470	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
J6320_20475	COG0228	four-way junction DNA binding
J6320_20480	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
J6320_20485	COG4137	Cytochrome C assembly protein
J6320_20490	COG4536	flavin adenine dinucleotide binding
J6320_20500	COG1854	S-ribosylhomocysteine lyase activity
J6320_20515	COG0612	Peptidase, M16
J6320_20520	COG1238	metal cluster binding
J6320_20530	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
J6320_20535	COG0511	ligase activity, forming carbon-carbon bonds
J6320_20535	COG5016	pyruvate
J6320_20540	COG3630	sodium ion export across plasma membrane
J6320_20605	COG0527	aspartate kinase activity
J6320_20610	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
J6320_20615	COG2137	regulation of response to DNA damage stimulus
J6320_20620	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
J6320_20625	COG1546	Belongs to the CinA family
J6320_20630	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
J6320_20635	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
J6320_20645	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
J6320_20650	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
J6320_20660	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
J6320_20665	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
J6320_20670	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
J6320_20675	COG0148	phosphopyruvate hydratase activity
J6320_20680	COG0504	CTP synthase activity
J6320_20685	COG3956	TIGRFAM MazG family protein
J6320_20690	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
J6320_20695	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
J6320_20710	COG0736	holo-[acyl-carrier-protein] synthase activity
J6320_20715	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
J6320_20720	COG1381	Involved in DNA repair and RecF pathway recombination
J6320_20725	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
J6320_20735	COG0681	Belongs to the peptidase S26 family
J6320_20740	COG0481	GTPase activity
J6320_20745	COG3086	response to oxidative stress
J6320_20760	COG1595	DNA-templated transcription, initiation
J6320_20765	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
J6320_20775	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
J6320_20795	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
J6320_20800	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
J6320_20805	COG3079	Belongs to the UPF0149 family
J6320_20810	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
J6320_20820	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
J6320_20825	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
J6320_20830	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
J6320_20855	COG0668	transmembrane transport
J6320_20860	COG0191	fructose-bisphosphate aldolase activity
J6320_20875	COG4771	TonB-dependent receptor
J6320_20880	COG0583	DNA-binding transcription factor activity
J6320_20885	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
J6320_20890	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
J6320_20905	COG2356	endonuclease I
J6320_20910	COG1385	rRNA (uridine-N3-)-methyltransferase activity
J6320_20915	COG0189	ligase activity
J6320_20920	COG1678	Uncharacterized ACR, COG1678
J6320_20925	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
J6320_20940	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
J6320_20945	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
J6320_20950	COG0762	integral membrane protein
J6320_20955	COG1872	DUF167
J6320_20965	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
J6320_20970	COG0635	Involved in the biosynthesis of porphyrin-containing compound
J6320_20975	COG2066	Belongs to the glutaminase family
J6320_20985	COG0220	tRNA (guanine-N7-)-methyltransferase activity
J6320_20995	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
J6320_21115	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
J6320_21120	COG1609	Transcriptional regulator
J6320_21125	COG3394	polysaccharide catabolic process
J6320_21130	COG1486	melibiose metabolic process
J6320_21135	COG1447	Phosphotransferase system cellobiose-specific component IIA
J6320_21140	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
J6320_21145	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
J6320_21150	COG0726	polysaccharide deacetylase
J6320_21165	COG1278	Cold shock
J6320_21290	COG1028	Short-chain dehydrogenase reductase Sdr
J6320_21305	COG0795	lipopolysaccharide-transporting ATPase activity
J6320_21310	COG0795	lipopolysaccharide-transporting ATPase activity
J6320_21315	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
J6320_21320	COG2927	DNA polymerase III (CHI subunit)
J6320_21325	COG0525	valine-tRNA ligase activity
J6320_21335	COG0456	acetyltransferase
J6320_21365	COG0540	Belongs to the ATCase OTCase family
J6320_21370	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
J6320_21375	COG0251	oxidation-reduction process
J6320_21380	COG0204	Acyl-transferase
J6320_21385	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
J6320_21390	COG5007	Belongs to the BolA IbaG family
J6320_21400	COG2854	intermembrane phospholipid transfer
J6320_21405	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
J6320_21410	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
J6320_21415	COG1127	ABC transporter
J6320_21425	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
J6320_21425	COG0517	IMP dehydrogenase activity
J6320_21435	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
J6320_21440	COG1137	ATPase activity
J6320_21450	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
J6320_21455	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
J6320_21460	COG1660	Displays ATPase and GTPase activities
J6320_21465	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
J6320_21470	COG2239	Acts as a magnesium transporter
J6320_21475	COG0312	modulator of DNA gyrase
J6320_21480	COG3028	Belongs to the UPF0307 family
J6320_21485	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
J6320_21490	COG0564	pseudouridine synthase activity
J6320_21500	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
J6320_21505	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
J6320_21510	COG0312	modulator of DNA gyrase
J6320_21515	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
J6320_21520	COG3164	Protein of unknown function
J6320_21530	COG0424	maF-like protein
J6320_21535	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
J6320_21540	COG1792	Involved in formation and maintenance of cell shape
J6320_21545	COG1077	Cell shape determining protein MreB Mrl
J6320_21590	COG1459	type II secretion system
J6320_21595	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
J6320_21605	COG3409	Peptidoglycan-binding domain 1 protein
J6320_21605	COG3267	Type II secretory pathway component ExeA
J6320_21610	COG1450	Type ii and iii secretion system protein
J6320_21630	COG2200	EAL domain
J6320_21630	COG2199	diguanylate cyclase activity
J6320_21640	COG0629	single-stranded DNA binding
J6320_21655	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
J6320_21665	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
J6320_21670	COG0527	aspartate kinase activity
J6320_21675	COG1410	methionine synthase
J6320_21675	COG0646	methionine synthase
J6320_21735	COG0175	sulfate reduction
J6320_21740	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
J6320_21745	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
J6320_21765	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
J6320_21770	COG0735	belongs to the Fur family
J6320_21780	COG0166	Belongs to the GPI family
J6320_21785	COG0432	Pfam Uncharacterised protein family UPF0047
J6320_21790	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
J6320_21820	COG2965	DNA replication, synthesis of RNA primer
J6320_21825	COG0360	Binds together with S18 to 16S ribosomal RNA
J6320_21830	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
J6320_21835	COG0338	D12 class N6 adenine-specific DNA methyltransferase
J6320_21845	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
J6320_21850	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
J6320_21880	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
J6320_21890	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
J6320_21890	COG0678	peroxiredoxin activity
J6320_21895	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
J6320_21905	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
J6320_21905	COG0165	Argininosuccinate lyase
J6320_21910	COG0137	argininosuccinate synthase activity
J6320_21920	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
J6320_21930	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
J6320_21940	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
J6320_21945	COG0527	aspartate kinase activity
J6320_21945	COG0460	homoserine dehydrogenase
J6320_21950	COG0626	cystathionine gamma-synthase activity
J6320_21955	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
J6320_21960	COG0281	malic enzyme
J6320_21975	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
J6320_21980	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
J6320_22000	COG2923	Belongs to the DsrF TusC family
J6320_22005	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
J6320_22010	COG2964	Protein conserved in bacteria
J6320_22015	COG0545	Peptidyl-prolyl cis-trans isomerase
J6320_22030	COG1446	asparaginase
J6320_22035	COG1047	Peptidyl-prolyl cis-trans
J6320_22050	COG2249	NAD(P)H dehydrogenase (quinone) activity
J6320_22055	COG0488	(ABC) transporter
J6320_22065	COG0429	hydrolase of the alpha beta-hydrolase fold
J6320_22075	COG3954	Phosphoribulokinase
J6320_22080	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
J6320_22100	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
J6320_22105	COG0512	Glutamine amidotransferase of anthranilate synthase
J6320_22120	COG0180	Tryptophanyl-tRNA synthetase
J6320_22125	COG0546	phosphoglycolate phosphatase activity
J6320_22130	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
J6320_22135	COG0557	exoribonuclease II activity
J6320_22140	COG1959	2 iron, 2 sulfur cluster binding
J6320_22145	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
J6320_22145	COG1017	nitric oxide dioxygenase activity
J6320_22150	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
J6320_22155	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
J6320_22160	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
J6320_22165	COG0330	HflC and HflK could
J6320_22170	COG0330	HflC and HflK could
J6320_22175	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
J6320_22185	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
J6320_22190	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
J6320_22200	COG0802	atpase or kinase
J6320_22205	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
J6320_22260	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
J6320_22265	COG1162	GTPase activity
J6320_22270	COG0688	phosphatidylethanolamine metabolic process
J6320_22290	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
J6320_22295	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
J6320_22300	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
J6320_22305	COG1045	serine acetyltransferase
J6320_22310	COG4942	peptidase
J6320_22330	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
J6320_22335	COG1053	succinate dehydrogenase
J6320_22340	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
J6320_22345	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
J6320_22350	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
J6320_22365	COG1509	lysine 2,3-aminomutase activity
J6320_22370	COG1285	pathogenesis
J6320_22380	COG0459	protein refolding
J6320_22390	COG0534	Mate efflux family protein
J6320_22405	COG3678	ATP-independent chaperone mediated protein folding
J6320_22410	COG0745	RESPONSE REGULATOR receiver
J6320_22415	COG2205	protein histidine kinase activity
J6320_22425	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
J6320_22430	COG3030	protein affecting phage T7 exclusion by the F plasmid
J6320_22435	COG1027	Aspartate ammonia-lyase
J6320_22440	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
J6320_22445	COG4232	protein-disulfide reductase activity
J6320_22455	COG3263	regulation of cellular component size
J6320_22465	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
J6320_22490	COG2814	Major facilitator Superfamily
J6320_22505	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
J6320_22510	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
J6320_22515	COG0511	ligase activity, forming carbon-carbon bonds
J6320_22520	COG0439	Biotin carboxylase
J6320_22525	COG2264	protein methyltransferase activity
J6320_22530	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
J6320_22535	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
J6320_22545	COG0488	(ABC) transporter
J6320_22610	COG0531	amino acid
J6320_22615	COG3710	Transcriptional regulator
J6320_22620	COG0789	Transcriptional regulator
J6320_22630	COG0151	Belongs to the GarS family
J6320_22650	COG1253	flavin adenine dinucleotide binding
J6320_22655	COG3068	Protein conserved in bacteria
J6320_22665	COG1573	uracil-dna glycosylase
J6320_22670	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
J6320_22675	COG2816	NAD+ diphosphatase activity
J6320_22680	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
J6320_22685	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
J6320_22695	COG0222	ribosome binding
J6320_22700	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
J6320_22715	COG0250	Participates in transcription elongation, termination and antitermination
J6320_22720	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
J6320_22725	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
J6320_22755	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
J6320_22755	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
J6320_22760	COG0812	UDP-N-acetylmuramate dehydrogenase activity
J6320_22770	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
J6320_22835	COG4206	TonB-dependent receptor
J6320_22855	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
J6320_22860	COG0534	Mate efflux family protein
J6320_22865	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
J6320_22870	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
J6320_22875	COG2937	Belongs to the GPAT DAPAT family
J6320_22880	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
J6320_22885	COG3161	chorismate lyase activity
J6320_22890	COG1580	Controls the rotational direction of flagella during chemotaxis
J6320_22895	COG0705	Rhomboid family
J6320_22900	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
J6320_22910	COG2177	Part of the ABC transporter FtsEX involved in
J6320_22915	COG2884	Cell division ATP-binding protein ftsE
J6320_22920	COG0552	protein localization to endoplasmic reticulum
J6320_22925	COG0742	ribosomal rna small subunit methyltransferase
J6320_22935	COG2095	MarC family integral membrane protein
J6320_22975	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
J6320_22980	COG0640	Transcriptional regulator
J6320_22985	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
J6320_22990	COG1280	lysine exporter protein (LysE YggA)
J6320_22995	COG2267	carboxylic ester hydrolase activity
J6320_23000	COG0561	phosphatase activity
J6320_23015	COG3148	PFAM DTW domain containing protein
J6320_23020	COG2199	diguanylate cyclase activity
J6320_23020	COG3287	FIST C domain
J6320_23020	COG2200	EAL domain
J6320_23025	COG1011	Hydrolase
J6320_23030	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
J6320_23045	COG0019	diaminopimelate decarboxylase activity
J6320_23055	COG1965	Belongs to the frataxin family
J6320_23060	COG3072	Adenylate cyclase
J6320_23065	COG0181	hydroxymethylbilane synthase activity
J6320_23070	COG1587	Uroporphyrinogen-III synthase
J6320_23075	COG2959	enzyme of heme biosynthesis
J6320_23080	COG3071	HemY protein
J6320_23120	COG0633	Ferredoxin
J6320_23125	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
J6320_23140	COG3118	belongs to the thioredoxin family
J6320_23150	COG0248	Ppx GppA phosphatase
J6320_23160	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
J6320_23170	COG0514	ATP-dependent DNA helicase (RecQ)
J6320_23175	COG2962	Rard protein
J6320_23185	COG1280	lysine exporter protein (LysE YggA)
J6320_23190	COG0405	Gamma-glutamyltransferase
J6320_23205	COG3220	belongs to the UPF0276 family
J6320_23235	COG0006	proline dipeptidase activity
J6320_23235	COG0006	proline dipeptidase activity
J6320_23250	COG2104	thiamine diphosphate biosynthetic process
J6320_23255	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
J6320_23275	COG2132	Multicopper oxidase
J6320_23320	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
J6320_23340	COG0009	L-threonylcarbamoyladenylate synthase
J6320_23345	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
J6320_23355	COG0551	DNA topoisomerase type I activity
J6320_23360	COG2922	Belongs to the Smg family
J6320_23365	COG0758	DNA mediated transformation
J6320_23375	COG0242	peptide deformylase activity
J6320_23380	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
J6320_23385	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
J6320_23385	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
J6320_23390	COG0569	domain protein
J6320_23395	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
J6320_23405	COG1272	protein, Hemolysin III
J6320_23410	COG4326	sporulation control protein
J6320_23420	COG3084	Protein conserved in bacteria
J6320_23430	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
J6320_23435	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
J6320_23440	COG0204	Acyl-transferase
J6320_23455	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
J6320_23475	COG0606	chelatase, subunit chli
J6320_23485	COG3978	acetolactate synthase activity
J6320_23490	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
J6320_23495	COG0129	dihydroxy-acid dehydratase activity
J6320_23505	COG0583	DNA-binding transcription factor activity
J6320_23510	COG2814	Major facilitator Superfamily
J6320_23520	COG0765	amino acid transport
J6320_23530	COG0355	proton-transporting ATP synthase activity, rotational mechanism
J6320_23535	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
J6320_23540	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
J6320_23545	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
J6320_23550	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
J6320_23555	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
J6320_23565	COG0356	it plays a direct role in the translocation of protons across the membrane
J6320_23570	COG3312	ion transport
J6320_23575	COG1475	DNA binding
J6320_23580	COG1192	Involved in chromosome partitioning
J6320_23585	COG0357	Ribosomal RNA small subunit methyltransferase G
J6320_23590	COG0445	tRNA wobble uridine modification
J6320_23595	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
J6320_23690	COG4974	Belongs to the 'phage' integrase family
J6320_23700	COG0706	membrane insertase activity
J6320_23710	COG0594	ribonuclease P activity
J6320_23720	COG1126	abc transporter atp-binding protein