locus-tag	class	description
K04M5_00010	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
K04M5_00020	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
K04M5_00030	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
K04M5_00040	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
K04M5_00070	ENOG4108ZNX	Heat shock protein
K04M5_00080	ENOG4105JKW	Valine--pyruvate aminotransferase
K04M5_00090	ENOG4107T9C	Alpha amylase catalytic region
K04M5_00100	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
K04M5_00110	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
K04M5_00140	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
K04M5_00170	ENOG4105D3Z	quinone oxidoreductase, yhdh yhfp family
K04M5_00180	ENOG4105CHU	acetyl-coa acetyltransferase
K04M5_00190	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
K04M5_00200	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
K04M5_00210	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
K04M5_00220	ENOG4108RR8	protoporphyrinogen oxidase
K04M5_00290	ENOG4105EMY	transcriptional regulator
K04M5_00300	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
K04M5_00310	ENOG4105W0Z	cytoplasmic protein
K04M5_00320	ENOG4105BZS	acriflavin resistance protein
K04M5_00330	ENOG410624X	efflux transporter, rnd family, mfp subunit
K04M5_00340	ENOG41067SE	Tetr family transcriptional regulator
K04M5_00350	ENOG4105C4R	Atp-dependent dna helicase
K04M5_00360	ENOG4105MPD	Cytochrome
K04M5_00430	ENOG4108JQ6	ABC transporter
K04M5_00440	ENOG4107QSI	ABC, transporter
K04M5_00450	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
K04M5_00460	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
K04M5_00480	ENOG4105DIQ	Transcriptional regulator
K04M5_00490	ENOG41064T2	transcriptional regulator, lysR family
K04M5_00500	ENOG41090TI	Catalyzes the excretion of spermidine (By similarity)
K04M5_00510	ENOG4108ZBZ	Catalyzes the excretion of spermidine (By similarity)
K04M5_00520	ENOG4105C01	Dihydroxy-acid dehydratase
K04M5_00530	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
K04M5_00540	ENOG4105C6Z	Gluconate
K04M5_00550	ENOG4108UHU	Aldolase
K04M5_00560	ENOG4107U5R	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity)
K04M5_00570	ENOG4107RSM	transcriptional regulator
K04M5_00580	ENOG4105DC8	reductase
K04M5_00590	ENOG4105D6S	protein involved in catabolism of external DNA
K04M5_00600	ENOG4105DGW	oligopeptidase A
K04M5_00610	ENOG4108VVK	transcriptional Regulator, AsnC
K04M5_00620	ENOG4105BZU	Histidine kinase
K04M5_00630	ENOG4105FFN	Specifically methylates the guanosine in position 1516 of 16S rRNA (By similarity)
K04M5_00650	ENOG4105EMK	carboxylate amino acid amine transporter
K04M5_00660	ENOG4108M6U	Universal stress protein A
K04M5_00670	ENOG41090A1	ferritin
K04M5_00680	ENOG4108V6B	universal stress protein B
K04M5_00690	ENOG4105CBX	hi0933 family
K04M5_00700	ENOG4108JUA	Transcriptional regulator
K04M5_00750	ENOG4107TE5	Lipid kinase
K04M5_00810	ENOG4105DSF	transport protein
K04M5_00820	ENOG4105BZU	Histidine kinase
K04M5_00840	ENOG4105CGY	Dna recombination protein
K04M5_00850	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
K04M5_00860	ENOG4105JC1	sterol-binding domain protein
K04M5_00870	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
K04M5_00880	ENOG4105WKS	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
K04M5_00890	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
K04M5_00900	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
K04M5_00910	ENOG4105F8V	Hydrolase, tatD family
K04M5_00920	ENOG4105D52	delta-aminolevulinic acid dehydratase
K04M5_00930	ENOG4105KD7	acetyltransferase
K04M5_00950	ENOG4105C2M	dna polymerase I
K04M5_00960	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
K04M5_00970	ENOG4106RE7	Cytochrome
K04M5_00990	ENOG4105ZR3	A GTPase-activating protein (GAP) that modifies Der EngA GTPase function. May play a role in ribosome biogenesis (By similarity)
K04M5_01000	ENOG4105XCT	Protein of unknown function (DUF2489)
K04M5_01010	ENOG4105D4P	Coproporphyrinogen iii oxidase
K04M5_01020	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
K04M5_01030	ENOG4105BZU	Histidine kinase
K04M5_01040	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
K04M5_01050	ENOG4105CUX	Signal transduction histidine kinase
K04M5_01070	ENOG4105C5F	glutamine synthetase
K04M5_01090	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
K04M5_01110	ENOG4107S2Z	UPF0761 membrane protein
K04M5_01120	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
K04M5_01130	ENOG4105SUU	thioesterase domain
K04M5_01150	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
K04M5_01160	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
K04M5_01170	ENOG4105VEJ	Heat shock protein
K04M5_01180	ENOG4108XKW	General secretion pathway protein C
K04M5_01200	ENOG4107QHF	type ii secretion system protein e
K04M5_01210	ENOG4105D7Q	type ii secretion system
K04M5_01220	ENOG4108VAU	general secretion pathway protein G
K04M5_01230	ENOG4105VWV	general secretion pathway protein h
K04M5_01240	ENOG4105X5Z	General secretion pathway protein I
K04M5_01250	ENOG4108WWZ	General secretion pathway protein J
K04M5_01260	ENOG4108RTD	type II secretion system protein K
K04M5_01270	ENOG4108BY5	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins (By similarity)
K04M5_01280	ENOG4105U1E	general secretion pathway protein M
K04M5_01290	ENOG4105PIC	general secretion pathway protein N
K04M5_01310	ENOG4107RK2	ADP-ribose diphosphatase NudE
K04M5_01320	ENOG4107RUK	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins (By similarity)
K04M5_01330	ENOG4105MJ2	Competence protein
K04M5_01340	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
K04M5_01360	ENOG4105BZM	domain protein
K04M5_01380	ENOG4108RRZ	Transcription elongation factor GreB
K04M5_01400	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
K04M5_01410	ENOG4105E0F	Histidine kinase
K04M5_01420	ENOG4105C2W	permease
K04M5_01430	ENOG4105CB5	ATP-dependent DNA helicase recG
K04M5_01440	ENOG4105FE8	tRNA (Guanosine-2'-O-)-methyltransferase
K04M5_01450	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
K04M5_01460	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
K04M5_01470	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
K04M5_01500	ENOG4109015	Biopolymer transport protein exbD tolR
K04M5_01550	ENOG4108I5X	binding-protein-dependent transport systems inner membrane Component
K04M5_01560	ENOG4108IYQ	Binding-protein-dependent transport systems inner membrane component
K04M5_01570	ENOG4107QRA	Extracellular solute-binding protein, family 5
K04M5_01590	ENOG4108JQ7	(ABC) transporter
K04M5_01610	ENOG4105DSJ	YicC domain protein
K04M5_01620	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
K04M5_01630	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
K04M5_01640	ENOG4105D1S	lipid A biosynthesis
K04M5_01650	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
K04M5_01660	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
K04M5_01670	ENOG4105C8Q	Methyl-accepting chemotaxis
K04M5_01680	ENOG4105W5Q	DNA repair protein (RadC
K04M5_01690	ENOG4105KDC	50s ribosomal protein l28
K04M5_01720	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
K04M5_01730	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
K04M5_01740	ENOG4108JMC	lipopolysaccharide core biosynthesis protein
K04M5_01760	ENOG4106WTF	Glycosyl transferase, family 2
K04M5_01770	ENOG4105DKP	glycosyl transferase, family 9
K04M5_01780	ENOG41080IJ	Diacylglycerol kinase
K04M5_01790	ENOG4108W7E	Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position (By similarity)
K04M5_01800	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
K04M5_01810	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
K04M5_01890	ENOG4105DF3	Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta-cleavage pathway for the degradation of aromatic compounds (By similarity)
K04M5_01900	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
K04M5_01910	ENOG4105XA0	heptosyltransferase ii
K04M5_01930	ENOG4105NWR	lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase
K04M5_01960	ENOG4105CUI	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity)
K04M5_01970	ENOG4105E3R	(LipO)protein
K04M5_02020	ENOG4105DAY	polysaccharide export protein
K04M5_02070	ENOG4105CG5	Glycosyl transferase (Group 1
K04M5_02090	ENOG4107RA4	Glycosyl transferase (Group 1
K04M5_02120	ENOG4105CY0	Metallo-Beta-Lactamase
K04M5_02130	ENOG4105ESV	Glycosyl transferase, family 4
K04M5_02180	ENOG4105JEU	Glycosyl transferase, family 2
K04M5_02230	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
K04M5_02240	ENOG4105CP7	Triose-phosphate isomerase
K04M5_02290	ENOG4105CBT	Fructose-1,6-bisphosphatase
K04M5_02300	ENOG41065UX	Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA (By similarity)
K04M5_02310	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
K04M5_02320	ENOG4105EIS	1,4-dihydroxy-2-naphthoate octaprenyltransferase
K04M5_02380	ENOG4108YGG	dna repair protein
K04M5_02410	ENOG4106YYS	transcriptional regulatory protein
K04M5_02420	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
K04M5_02430	ENOG4105D9Q	decarboxylase (Beta subunit)
K04M5_02440	ENOG4107QSA	Oxaloacetate decarboxylase
K04M5_02470	ENOG4105DUA	(citrate (pro-3S)-lyase ligase
K04M5_02480	ENOG4105XGS	Covalent carrier of the coenzyme of citrate lyase (By similarity)
K04M5_02490	ENOG4105CI0	Citrate lyase
K04M5_02500	ENOG4105CHY	citrate lyase, alpha
K04M5_02510	ENOG4105YGP	holo-ACP synthase CitX
K04M5_02520	ENOG4108K6F	triphosphoribosyl-dephospho-CoA synthase
K04M5_02550	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
K04M5_02560	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
K04M5_02590	ENOG4105ETE	Transcriptional regulator (LacI family
K04M5_02600	ENOG4105C25	Primosomal protein n'
K04M5_02610	ENOG4105VFB	Binds the 23S rRNA (By similarity)
K04M5_02620	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
K04M5_02630	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
K04M5_02640	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
K04M5_02650	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
K04M5_02660	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
K04M5_02670	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
K04M5_02680	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
K04M5_02690	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
K04M5_02700	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
K04M5_02710	ENOG41083MP	50s ribosomal protein l29
K04M5_02720	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
K04M5_02730	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
K04M5_02740	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
K04M5_02750	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
K04M5_02760	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
K04M5_02770	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
K04M5_02780	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
K04M5_02800	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
K04M5_02810	ENOG4105VPB	50S ribosomal protein L30
K04M5_02820	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
K04M5_02830	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
K04M5_02850	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
K04M5_02860	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
K04M5_02870	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
K04M5_02880	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
K04M5_02890	ENOG4108ZT0	50S ribosomal protein l17
K04M5_02910	ENOG4108V1T	peptidylprolyl cis-trans isomerase
K04M5_02930	ENOG4107YB6	acetyltransferase, (GNAT) family
K04M5_02940	ENOG4105C1J	atp-dependent rna helicase
K04M5_02960	ENOG4107RNS	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic
K04M5_02970	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
K04M5_02980	ENOG4105C11	sulfate adenylyltransferase), subunit 2
K04M5_02990	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
K04M5_03010	ENOG4108I67	Catalyzes the synthesis of activated sulfate (By similarity)
K04M5_03060	ENOG4108I0Y	(ABC) transporter
K04M5_03090	ENOG4108UUE	Transcriptional regulator
K04M5_03100	ENOG41061GZ	Protein of unknown function (DUF1107)
K04M5_03110	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
K04M5_03120	ENOG4105CFU	surface antigen
K04M5_03130	ENOG4105MA0	exported protein
K04M5_03140	ENOG41066HZ	AIG2-like family
K04M5_03160	ENOG4105F0N	pyrophosphate phospho-hydrolase
K04M5_03170	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
K04M5_03180	ENOG4105DFU	Cell wall formation (By similarity)
K04M5_03190	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
K04M5_03200	ENOG4105DP9	ABC transporter
K04M5_03210	ENOG4106SMU	thiamine transporter membrane protein
K04M5_03220	ENOG4107T0D	ABC, transporter
K04M5_03230	ENOG4105CC0	LysR family Transcriptional regulator
K04M5_03240	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
K04M5_03280	ENOG410682Y	Regulates arginine biosynthesis genes (By similarity)
K04M5_03290	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
K04M5_03310	ENOG4105EAH	synthase
K04M5_03320	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
K04M5_03330	ENOG4105K46	50S ribosomal protein l27
K04M5_03340	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
K04M5_03350	ENOG4105DWK	Membrane
K04M5_03360	ENOG4107XM3	UPF0442 protein
K04M5_03370	ENOG4108YYV	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity)
K04M5_03380	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
K04M5_03390	ENOG4105NWN	ApaG protein
K04M5_03400	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
K04M5_03410	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
K04M5_03420	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
K04M5_03430	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
K04M5_03440	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
K04M5_03460	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
K04M5_03470	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
K04M5_03480	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
K04M5_03490	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
K04M5_03530	ENOG41064T2	transcriptional regulator, lysR family
K04M5_03540	ENOG4108IQE	Amp-dependent synthetase and ligase
K04M5_03550	ENOG4105C7K	acetolactate synthase
K04M5_03560	ENOG4108ZP8	Acetolactate synthase small subunit
K04M5_03570	ENOG4105BZU	Histidine kinase
K04M5_03590	ENOG4105CA9	Pyruvate kinase
K04M5_03600	ENOG410804X	Transcriptional regulator
K04M5_03610	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
K04M5_03630	ENOG4105CMT	Dihydroxyacetone kinase
K04M5_03640	ENOG4108UTZ	Dihydroxyacetone kinase
K04M5_03670	ENOG4105E61	Mannitol repressor protein
K04M5_03680	ENOG4107SQ3	mannitol-1-phosphate 5-dehydrogenase
K04M5_03690	ENOG4105CTS	PTS system mannitol-specific
K04M5_03730	ENOG4105D01	(LipO)protein
K04M5_03750	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
K04M5_03760	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
K04M5_03770	ENOG4105KTH	gatB Yqey
K04M5_03780	ENOG4105VCC	30S ribosomal protein S21
K04M5_03790	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
K04M5_03800	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
K04M5_03810	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
K04M5_03820	ENOG4107ZVW	dihydroneopterin aldolase
K04M5_03830	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
K04M5_03840	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
K04M5_03850	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
K04M5_03880	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
K04M5_03890	ENOG4106MWK	domain protein
K04M5_03900	ENOG4105CJ3	phosphate transporter
K04M5_03910	ENOG4107IX6	phosphate transport regulator
K04M5_03920	ENOG4105I7R	Adenylate cyclase
K04M5_03940	ENOG4105C8Q	Methyl-accepting chemotaxis
K04M5_03950	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
K04M5_03960	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
K04M5_03970	ENOG4105DFG	type I secretion outer membrane protein
K04M5_03980	ENOG41087AY	ADP-Ribose pyrophosphatase
K04M5_03990	ENOG4108SX3	cytoplasmic protein
K04M5_04000	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
K04M5_04010	ENOG4105IPS	esterase
K04M5_04020	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
K04M5_04030	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
K04M5_04040	ENOG4105C0H	protease
K04M5_04050	ENOG4105C0H	protease
K04M5_04060	ENOG4108W2Q	Cytochrome d ubiquinol oxidase subunit III
K04M5_04070	ENOG4105D6Z	AFG1 family ATPase
K04M5_04080	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
K04M5_04090	ENOG4108UJD	30S ribosomal protein S9
K04M5_04100	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
K04M5_04110	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
K04M5_04120	ENOG4105EIX	cytochrome c1
K04M5_04130	ENOG4107MKT	Stringent starvation protein a
K04M5_04140	ENOG4105KB2	stringent starvation protein b
K04M5_04170	ENOG4105W4M	Transport-associated protein
K04M5_04180	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
K04M5_04190	ENOG41082RQ	UPF0102 protein
K04M5_04210	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
K04M5_04220	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
K04M5_04230	ENOG41063Y6	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
K04M5_04240	ENOG4105CJN	penicillin-binding protein
K04M5_04250	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
K04M5_04260	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
K04M5_04270	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
K04M5_04280	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
K04M5_04300	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
K04M5_04310	ENOG4105DFU	Cell wall formation (By similarity)
K04M5_04320	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
K04M5_04330	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
K04M5_04340	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
K04M5_04350	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
K04M5_04370	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
K04M5_04380	ENOG4105M6F	mutator MutT protein
K04M5_04390	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
K04M5_04400	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
K04M5_04410	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
K04M5_04440	ENOG4105EJ9	Membrane
K04M5_04450	ENOG4105VP0	transcriptional regulator, lysR family
K04M5_04460	ENOG4105EN6	Membrane
K04M5_04470	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
K04M5_04480	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
K04M5_04490	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
K04M5_04510	ENOG4105BZ8	glutamate synthase
K04M5_04520	ENOG4105CBC	glutamate synthase
K04M5_04550	ENOG4105N5T	Radical SAM Protein
K04M5_04570	ENOG4105BZU	Histidine kinase
K04M5_04590	ENOG41065U4	response regulator
K04M5_04610	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
K04M5_04640	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
K04M5_04650	ENOG4105D98	threonine synthase
K04M5_04670	ENOG4108VKA	Acts as a radical domain for damaged PFL and possibly other radical proteins (By similarity)
K04M5_04680	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
K04M5_04690	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
K04M5_04720	ENOG4105BZG	amino acid carrier protein
K04M5_04730	ENOG4105D1Q	UPF0246 protein
K04M5_04740	ENOG4105C1J	atp-dependent rna helicase
K04M5_04750	ENOG4107S47	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (By similarity)
K04M5_04760	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
K04M5_04770	ENOG41071R3	Low-potential electron donor to a number of redox enzymes (By similarity)
K04M5_04780	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
K04M5_04790	ENOG4105T95	Thiol disulfide interChange protein
K04M5_04800	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
K04M5_04810	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
K04M5_04820	ENOG4105CRK	lysyL-tRNA synthetase
K04M5_04830	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
K04M5_04860	ENOG4105CPC	Aldo Keto reductase
K04M5_04880	ENOG4105IRT	Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair (By similarity)
K04M5_04890	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
K04M5_04900	ENOG4108HRM	phosphoenolpyruvate--protein phosphotransferase
K04M5_04910	ENOG4105HF0	Membrane
K04M5_04920	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
K04M5_04930	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
K04M5_04960	ENOG41063Z6	transcriptional regulator, lysR family
K04M5_04970	ENOG41080HT	Transcriptional regulator, arsr family
K04M5_04980	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
K04M5_04990	ENOG4105CJR	Integral membrane protein (MviN
K04M5_05000	ENOG4105DTN	riboflavin biosynthesis protein ribF
K04M5_05010	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
K04M5_05020	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
K04M5_05030	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
K04M5_05040	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
K04M5_05060	ENOG4108NEV	two component transcriptional regulator, LytTR family
K04M5_05070	ENOG4108HRK	Histidine kinase
K04M5_05110	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
K04M5_05120	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
K04M5_05130	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
K04M5_05140	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
K04M5_05150	ENOG4105EHE	chorismate mutase- prephenate dehydrogenase
K04M5_05160	ENOG4105DR5	peptidase
K04M5_05180	ENOG4105C5H	ABC transporter
K04M5_05190	ENOG4107SC1	transglycosylase
K04M5_05200	ENOG4105R9M	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region (By similarity)
K04M5_05210	ENOG4108K16	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
K04M5_05230	ENOG4108WPH	sigma 54 modulation protein ribosomal protein S30EA
K04M5_05250	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
K04M5_05260	ENOG4105C34	Pseudouridine synthase
K04M5_05270	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
K04M5_05280	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
K04M5_05410	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
K04M5_05420	ENOG4105CFP	Peptidase U32
K04M5_05430	ENOG4105DH7	May be involved in recombination (By similarity)
K04M5_05440	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
K04M5_05450	ENOG4105BZU	Histidine kinase
K04M5_05470	ENOG4105C9X	ppx gppa phosphatase
K04M5_05480	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
K04M5_05490	ENOG4105C8U	phosphate abc transporter
K04M5_05500	ENOG4105E2Z	phosphate ABC transporter (Permease
K04M5_05510	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
K04M5_05530	ENOG4105CSR	polyphosphate kinase 2
K04M5_05540	ENOG4106N3A	copper homeostasis protein cutc
K04M5_05550	ENOG4105D3R	alkyl hydroperoxide reductase
K04M5_05560	ENOG4105C5Q	Transcriptional regulator
K04M5_05570	ENOG4107QP3	malate synthase g
K04M5_05580	ENOG4108I9X	Isocitrate lyase
K04M5_05590	ENOG4105W87	Cbs domain
K04M5_05610	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
K04M5_05620	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
K04M5_05630	ENOG4105VIE	preprotein translocase, subunit YajC
K04M5_05640	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
K04M5_05650	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
K04M5_05680	ENOG4105ECY	inositol monophosphatase
K04M5_05690	ENOG4105CVS	RNA methyltransferase TrmH family, group 1
K04M5_05700	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
K04M5_05710	ENOG4105C3J	Cysteine desulfurase
K04M5_05720	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
K04M5_05730	ENOG4108Z4V	iron-sulfur cluster assembly
K04M5_05740	ENOG4108SWN	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA (By similarity)
K04M5_05750	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
K04M5_05760	ENOG4108ZIT	Ferredoxin, 2FE-2S
K04M5_05770	ENOG4105WVQ	Fe-S assembly protein IscX
K04M5_05780	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
K04M5_05790	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
K04M5_05800	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
K04M5_05820	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
K04M5_05830	ENOG4105CUT	histidyl-tRNA synthetase
K04M5_05840	ENOG4105N21	Membrane
K04M5_05850	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
K04M5_05860	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
K04M5_05890	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
K04M5_05900	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
K04M5_05910	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
K04M5_05920	ENOG4105DFP	Integrase
K04M5_06060	ENOG4107S6Z	Na H antiporter
K04M5_06080	ENOG4106HK8	GPR1 FUN34 yaaH family protein
K04M5_06090	ENOG4105BZG	amino acid carrier protein
K04M5_06100	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
K04M5_06120	ENOG4108IQK	o-acetylhomoserine
K04M5_06130	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
K04M5_06170	ENOG4105DGM	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
K04M5_06180	ENOG4105ETT	transcriptional Regulator, LysR family
K04M5_06220	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
K04M5_06230	ENOG4108Z1B	Cyclase dehydrase
K04M5_06240	ENOG4105VDB	UPF0125 protein
K04M5_06250	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
K04M5_06270	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
K04M5_06290	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
K04M5_06300	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
K04M5_06320	ENOG4105CK2	sodium dicarboxylate symporter
K04M5_06330	ENOG4105CFG	Acts as a chaperone (By similarity)
K04M5_06340	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
K04M5_06400	ENOG4105CFC	Transporter
K04M5_06410	ENOG4108Z6B	deaminase
K04M5_06420	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
K04M5_06430	ENOG4108ETH	Formylglycinamide ribotide synthetase
K04M5_06490	ENOG4105CIN	aminoacyl-histidine dipeptidase
K04M5_06500	ENOG4105C7N	Xanthine uracil vitamin C permease
K04M5_06510	ENOG4105DYA	Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity)
K04M5_06520	ENOG4108DJV	Fermentation respiration switch protein
K04M5_06530	ENOG4108UVK	Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes. Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32 (By similarity)
K04M5_06540	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
K04M5_06550	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
K04M5_06560	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
K04M5_06570	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
K04M5_06600	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
K04M5_06610	ENOG4107YIM	Involved in the transcription termination process (By similarity)
K04M5_06620	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
K04M5_06630	ENOG4108ZAI	phosphatidylglycerophosphatase a
K04M5_06640	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
K04M5_06650	ENOG4105CTB	Polyprenyl synthetase
K04M5_06660	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
K04M5_06670	ENOG4105E14	MotA TolQ exbB proton channel
K04M5_06680	ENOG4106VK6	Flagellar motor protein
K04M5_06690	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
K04M5_06710	ENOG4105ETT	transcriptional Regulator, LysR family
K04M5_06730	ENOG4105M08	Membrane
K04M5_06740	ENOG4105EZ6	Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA (By similarity)
K04M5_06750	ENOG4105CIQ	May have a role in processing of nucleic acids. It is probably not an exonuclease
K04M5_06760	ENOG4105EWT	decarboxylase family
K04M5_06770	ENOG4105BZU	Histidine kinase
K04M5_06790	ENOG4107R1K	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
K04M5_06800	ENOG4108T6E	Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function (By similarity)
K04M5_06810	ENOG4105EXF	Zn-ribbon-containing, possibly nucleic-acid-binding protein
K04M5_06820	ENOG4105D01	(LipO)protein
K04M5_06830	ENOG4108UMI	ABC transporter, permease
K04M5_06840	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
K04M5_06850	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
K04M5_06860	ENOG4105D4X	repressor
K04M5_06870	ENOG4105C5Y	PTS System
K04M5_06880	ENOG4105CG3	alpha amylase, catalytic region
K04M5_06910	ENOG4108JYZ	YitT family
K04M5_06920	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
K04M5_06930	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
K04M5_06940	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
K04M5_06950	ENOG4108Z43	UPF0250 protein
K04M5_06960	ENOG4105DZ1	carboxypeptidase
K04M5_06970	ENOG4105K6T	rare lipoprotein A
K04M5_06980	ENOG4105CNI	cell division protein FtsW
K04M5_06990	ENOG4105CJN	penicillin-binding protein
K04M5_07000	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
K04M5_07010	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
K04M5_07020	ENOG4105DJF	DNA polymerase III, delta' subunit
K04M5_07030	ENOG4108U2H	Rare lipoprotein B
K04M5_07040	ENOG4105C8T	Leucyl-tRNA synthetase
K04M5_07050	ENOG4107PAI	alpha helical protein
K04M5_07060	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
K04M5_07070	ENOG4108JU5	Magnesium and cobalt efflux protein
K04M5_07080	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
K04M5_07090	ENOG4105C9A	Phoh family
K04M5_07100	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
K04M5_07110	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
K04M5_07320	ENOG4105C3G	gtp-binding protein
K04M5_07330	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
K04M5_07340	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
K04M5_07350	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
K04M5_07360	ENOG4105C1U	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein (By similarity)
K04M5_07370	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
K04M5_07380	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
K04M5_07390	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
K04M5_07400	ENOG4108YY7	Invasion gene expression up-regulator SirB
K04M5_07410	ENOG41063JG	Transcriptional regulator
K04M5_07420	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
K04M5_07430	ENOG4105CGH	5'-nucleotidase
K04M5_07440	ENOG4108Z66	YbaK ebsC protein
K04M5_07450	ENOG4105FE9	pseudouridine synthase
K04M5_07460	ENOG4108DG9	Smr protein MutS2
K04M5_07510	ENOG4105E2D	ec 3.2.1.52
K04M5_07540	ENOG4105C59	p-type ATPase
K04M5_07550	ENOG41081QG	Porin Gram-negative type
K04M5_07570	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
K04M5_07580	ENOG4105UYK	outer membrane protein a
K04M5_07670	ENOG4107R88	Chemotaxis protein (CheV)
K04M5_07680	ENOG4105BZU	Histidine kinase
K04M5_07690	ENOG4105K88	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
K04M5_07700	ENOG4108ZC9	flagellar basal-body rod protein flgc
K04M5_07710	ENOG4105W00	Flagellar hook capping protein
K04M5_07720	ENOG4105BZE	flagellar hook protein, FlgE
K04M5_07730	ENOG4108KPB	Flagellar basal-body rod protein FlgF
K04M5_07740	ENOG4105CGA	flagellar basal-body rod protein FlgG
K04M5_07750	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
K04M5_07760	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
K04M5_07770	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
K04M5_07790	ENOG4105DTJ	flagellar hook-associated protein
K04M5_07800	ENOG4105I03	Flagellin
K04M5_07810	ENOG4105I03	Flagellin
K04M5_07830	ENOG4105C5Y	PTS System
K04M5_07840	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
K04M5_07860	ENOG4105KZ7	phosphocarrier protein hpr
K04M5_07870	ENOG4105C6T	cysteine synthase
K04M5_07880	ENOG4105EXN	Sulfate transport protein CysZ
K04M5_07890	ENOG4107NPY	receptor for the septal ring structure, may anchor it to the inner-membrane (By similarity)
K04M5_07900	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
K04M5_07950	ENOG4107QX8	SPFH domain, Band 7 family protein
K04M5_07960	ENOG4105D1V	cellulose synthase operon protein YhjU
K04M5_07980	ENOG4105U74	cellulose biosynthesis protein BcsE
K04M5_08000	ENOG4105UTS	cellulose synthase operon protein YhjQ
K04M5_08010	ENOG4107QZ7	Cellulose synthase catalytic subunit
K04M5_08020	ENOG4107EEX	Cellulose synthase regulator protein
K04M5_08030	ENOG4105K2Z	endo-1,4-d-glucanase (EC 3.2.1.4)
K04M5_08040	ENOG4105EJG	cellulose synthase
K04M5_08050	ENOG4107QR8	Thioredoxin
K04M5_08060	ENOG4105E1F	short-chain dehydrogenase reductase
K04M5_08070	ENOG4105ECP	epimerase
K04M5_08130	ENOG4108RE9	Phosphodiesterase
K04M5_08170	ENOG4108DQ1	activator toxR
K04M5_08180	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
K04M5_08190	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
K04M5_08200	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
K04M5_08210	ENOG4105DUX	Transporter
K04M5_08220	ENOG4105MDZ	Transcriptional activator rfaH
K04M5_08230	ENOG4105CAQ	asparagine synthetase
K04M5_08240	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
K04M5_08250	ENOG4105E2R	ROK family
K04M5_08260	ENOG4105CE4	GlcNAc 6-P deacetylase
K04M5_08270	ENOG4105CI1	PTS System
K04M5_08280	ENOG4105CX6	glutaminyL-tRNA synthetase
K04M5_08290	ENOG41090R7	Ferric uptake
K04M5_08310	ENOG4105MHQ	Low-potential electron donor to a number of redox enzymes (By similarity)
K04M5_08330	ENOG4105EV9	Alpha Beta Hydrolase
K04M5_08340	ENOG4107CDU	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated (By similarity)
K04M5_08350	ENOG4107QIX	Phosphoglucomutase (EC 5.4.2.2
K04M5_08370	ENOG4107QNR	UPF0135 protein
K04M5_08380	ENOG4105BZN	citrate synthase
K04M5_08390	ENOG4108UTY	succinate dehydrogenase, cytochrome b556 subunit
K04M5_08400	ENOG4105N1I	succinate dehydrogenase, hydrophobic membrane anchor protein
K04M5_08410	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
K04M5_08420	ENOG4105E33	succinate dehydrogenase
K04M5_08430	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
K04M5_08440	ENOG4105C7S	Dehydrogenase
K04M5_08450	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
K04M5_08460	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
K04M5_08470	ENOG4105FAV	ABC, transporter
K04M5_08480	ENOG4105FDK	ABC transporter
K04M5_08490	ENOG4105NXV	High-affinity zinc uptake system protein
K04M5_08500	ENOG4107S4Z	Activates expression of the rhaBAD and rhaT operons (By similarity)
K04M5_08510	ENOG4105XFK	Ferrous iron transport protein A
K04M5_08560	ENOG4105C75	arginyL-tRNA synthetase
K04M5_08570	ENOG4106ZCM	YecM protein
K04M5_08590	ENOG4105NDH	peptidase s1 and s6 chymotrypsin hap
K04M5_08600	ENOG4105CIY	formyltetrahydrofolate deformylase
K04M5_08610	ENOG4105DVT	helicase
K04M5_08620	ENOG41072GX	Peptidase M22 Glycoprotease
K04M5_08640	ENOG4105R8X	Outer membrane lipoprotein Slp
K04M5_08650	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
K04M5_08660	ENOG4105CEY	Amp-dependent synthetase and ligase
K04M5_08670	ENOG4105ZIE	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity)
K04M5_08680	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
K04M5_08690	ENOG4107QMS	site-determining protein
K04M5_08700	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
K04M5_08710	ENOG4105VNG	YcgL domain-containing protein
K04M5_08720	ENOG4105CVE	Lytic murein transglycosylase
K04M5_08740	ENOG4105D9N	nucleoside
K04M5_08750	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
K04M5_08770	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
K04M5_08780	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
K04M5_08790	ENOG4105C2D	reductase
K04M5_08800	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
K04M5_08810	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
K04M5_08860	ENOG4105C84	Histidine ammonia-lyase
K04M5_08870	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
K04M5_08880	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
K04M5_08920	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
K04M5_08990	ENOG4105C1J	atp-dependent rna helicase
K04M5_09000	ENOG4107ZYR	domain protein
K04M5_09050	ENOG4105CNG	UPF0061 protein
K04M5_09060	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
K04M5_09070	ENOG410835K	Tripartite ATP-Independent Periplasmic transporter DctQ
K04M5_09080	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
K04M5_09100	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
K04M5_09110	ENOG4105CQZ	Histidine kinase
K04M5_09120	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
K04M5_09130	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
K04M5_09140	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
K04M5_09150	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
K04M5_09160	ENOG4105K70	DNA-binding protein
K04M5_09170	ENOG4105EIN	peptidylprolyl cis-trans isomerase
K04M5_09180	ENOG41083P1	competence protein ComEA helix-hairpin-helix repeat protein
K04M5_09210	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
K04M5_09220	ENOG4105DK2	UPF0207 protein
K04M5_09230	ENOG4105CHM	Aminotransferase
K04M5_09240	ENOG4105E4F	Isochorismate synthase
K04M5_09250	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
K04M5_09270	ENOG4108IPT	Naphthoate synthase
K04M5_09280	ENOG4105DNI	Converts SHCHC to OSB (By similarity)
K04M5_09290	ENOG4105CEY	Amp-dependent synthetase and ligase
K04M5_09310	ENOG4105HMI	Membrane
K04M5_09320	ENOG4108J8Q	Catalyzes the facilitated diffusion of 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) into the cell (By similarity)
K04M5_09410	ENOG4105EP1	Efflux transporter rnd family, mfp subunit
K04M5_09420	ENOG4105BZS	acriflavin resistance protein
K04M5_09450	ENOG4105C6T	cysteine synthase
K04M5_09460	ENOG4108XM1	transcriptional regulator AsnC family
K04M5_09480	ENOG4105C29	acyl-CoA thioesterase
K04M5_09490	ENOG4108MNP	Glycoprotein polysaccharide metabolism
K04M5_09520	ENOG4105BZU	Histidine kinase
K04M5_09540	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
K04M5_09560	ENOG4107SXA	Phosphorylase
K04M5_09580	ENOG4108NVR	Methyl-accepting chemotaxis
K04M5_09590	ENOG4105K59	histidine triad (HIT) protein
K04M5_09640	ENOG4105D0Y	UPF0227 protein
K04M5_09650	ENOG4105CEP	NADH dehydrogenase
K04M5_09680	ENOG4108JA2	transcriptioN-repair coupling factor
K04M5_09700	ENOG4105D60	lipoprotein releasing system transmembrane protein
K04M5_09710	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
K04M5_09720	ENOG4105D60	lipoprotein releasing system transmembrane protein
K04M5_09740	ENOG4108EQH	DNA internalization-related competence protein ComEC Rec2
K04M5_09750	ENOG4105BZ1	(ABC) transporter
K04M5_09760	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
K04M5_09770	ENOG4105W49	UPF0434 protein
K04M5_09780	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
K04M5_09790	ENOG4105ED1	spovr family
K04M5_09800	ENOG4106AKX	UPF0229 protein
K04M5_09810	ENOG4105CYN	Serine protein kinase
K04M5_09820	ENOG4105XWI	UPF0304 protein
K04M5_09840	ENOG4105F1A	Pyruvate formate-lyase
K04M5_09860	ENOG4105C6N	Formate acetyltransferase
K04M5_09890	ENOG4108JEH	abc transporter atp-binding protein
K04M5_09900	ENOG4105E89	ABC transporter
K04M5_09910	ENOG4105DSP	amino acid AbC transporter
K04M5_09940	ENOG4105CGK	Exodeoxyribonuclease III
K04M5_09950	ENOG4106428	Protein of unknown function (DUF2496)
K04M5_09960	ENOG4108URS	primosomal replication protein n''
K04M5_09970	ENOG4105EJ9	Membrane
K04M5_09980	ENOG4105DVT	helicase
K04M5_10000	ENOG4105SDR	Outer membrane protein OmpT
K04M5_10020	ENOG4108R99	pseudouridine synthase
K04M5_10040	ENOG4105VEQ	Cold shock protein
K04M5_10050	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
K04M5_10060	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
K04M5_10070	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
K04M5_10080	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
K04M5_10090	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
K04M5_10110	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
K04M5_10120	ENOG4105RKX	Protein of unknown function (DUF2498)
K04M5_10130	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
K04M5_10140	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
K04M5_10150	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
K04M5_10190	ENOG4105HP8	regulator of competence-specific genes
K04M5_10200	ENOG4105ETE	Transcriptional regulator (LacI family
K04M5_10210	ENOG4109039	Involved in the biogenesis of TorA. Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor (By similarity)
K04M5_10220	ENOG4106WF9	DNA-binding transcriptional regulator TorR
K04M5_10230	ENOG4107S90	membrAne
K04M5_10240	ENOG4106371	Methyltransferase
K04M5_10250	ENOG4105GHU	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity (By similarity)
K04M5_10260	ENOG4105DAH	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF (By similarity)
K04M5_10270	ENOG4105DUC	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division (By similarity)
K04M5_10310	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
K04M5_10320	ENOG4105PFA	Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity)
K04M5_10330	ENOG4105DA6	Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity)
K04M5_10340	ENOG41081XQ	Conserved Protein
K04M5_10350	ENOG4105C9M	aspartyl-trna synthetase
K04M5_10360	ENOG4105CDY	transcriptional regulatory protein
K04M5_10370	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
K04M5_10380	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
K04M5_10390	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
K04M5_10400	ENOG4105C4M	(Ubiquinol oxidase) subunit I
K04M5_10410	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
K04M5_10440	ENOG4107YD3	Thioesterase
K04M5_10450	ENOG4105E02	MotA TolQ exbB proton channel
K04M5_10460	ENOG4105M8F	Biopolymer transport protein exbD tolR
K04M5_10480	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
K04M5_10490	ENOG4105KCK	Peptidoglycan-associated lipoprotein
K04M5_10500	ENOG4105UFD	tol-pal system protein YbgF
K04M5_10510	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
K04M5_10530	ENOG4105Z6B	inner membrane protein yjfl
K04M5_10550	ENOG4106032	Glutathionylspermidine synthase
K04M5_10570	ENOG4105BZU	Histidine kinase
K04M5_10580	ENOG4108RNS	Exports L-alanine (By similarity)
K04M5_10610	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
K04M5_10620	ENOG4105C4M	(Ubiquinol oxidase) subunit I
K04M5_10670	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
K04M5_10680	ENOG4105BZS	acriflavin resistance protein
K04M5_10750	ENOG4108NVR	Methyl-accepting chemotaxis
K04M5_10760	ENOG4105FR9	TRNA-(Ms 2 io 6 A)-hydroxylase
K04M5_10780	ENOG4107R11	Transcriptional regulator
K04M5_10800	ENOG4105DCF	alanine dehydrogenase
K04M5_10810	ENOG4105EW9	transcriptional regulator AsnC family
K04M5_10820	ENOG4105CNU	cell division protein FtsK
K04M5_10830	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
K04M5_10840	ENOG4105D1H	recombination factor protein RarA
K04M5_10850	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
K04M5_10880	ENOG4105KSC	Transcriptional regulator, TraR DksA family
K04M5_10890	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
K04M5_10900	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
K04M5_10910	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
K04M5_10930	ENOG4105EWW	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
K04M5_10950	ENOG4105D0M	Protease HtpX homolog
K04M5_10970	ENOG4107FW0	short-chain dehydrogenase reductase
K04M5_11000	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
K04M5_11020	ENOG4105RHG	
K04M5_11040	ENOG4107QTF	adenylosuccinate lyase
K04M5_11050	ENOG41075W9	High frequency lysogenization protein HflD homolog
K04M5_11060	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
K04M5_11080	ENOG4107RE1	Inosine-guanosine kinase
K04M5_11090	ENOG4108YX2	DNA-binding protein
K04M5_11100	ENOG4107S6Z	Na H antiporter
K04M5_11110	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
K04M5_11120	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
K04M5_11130	ENOG4105CIH	Imidazole acetol-phosphate transaminase
K04M5_11150	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
K04M5_11190	ENOG4105K5B	UPF0225 protein
K04M5_11200	ENOG4105D58	Diguanylate phosphodiesterase
K04M5_11210	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
K04M5_11220	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
K04M5_11230	ENOG4105C8N	cysteinyl-tRNA synthetase
K04M5_11240	ENOG4107104	thymidine kinase
K04M5_11300	ENOG4105TMB	Formate nitrite transporter
K04M5_11350	ENOG4108J2R	molybdopterin oxidoreductase
K04M5_11380	ENOG4105E2M	Manganese-dependent inorganic pyrophosphatase
K04M5_11400	ENOG4108JQ2	peptide transport system atp-binding protein
K04M5_11410	ENOG4108JQ3	Peptide ABC transporter ATP-binding protein
K04M5_11420	ENOG4108EU3	peptide transport system, permease
K04M5_11430	ENOG4108I5W	peptide transport system, permease protein
K04M5_11440	ENOG4108J59	Extracellular solute-binding protein, family 5
K04M5_11450	ENOG4105E51	psp operon transcriptional activator
K04M5_11460	ENOG41087YS	Phage shock protein A
K04M5_11470	ENOG4105YYT	phage shock protein B
K04M5_11480	ENOG4105FM1	phage shock protein C
K04M5_11520	ENOG4108R3E	Dna-3-methyladenine glycosylase i
K04M5_11540	ENOG4107IFA	Lipase (EC 3.1.1.3)
K04M5_11550	ENOG4105C28	cystathionine
K04M5_11560	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
K04M5_11570	ENOG4105C8J	)-transporter
K04M5_11580	ENOG4108W1A	pseudouridine synthase
K04M5_11600	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
K04M5_11610	ENOG4105EJ7	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity)
K04M5_11620	ENOG4108JUA	Transcriptional regulator
K04M5_11640	ENOG4108T9J	Cdp-alcohol phosphatidyltransferase
K04M5_11650	ENOG4108VGW	abc transporter atp-binding protein
K04M5_11660	ENOG4105CXZ	ABC transporter, permease
K04M5_11670	ENOG4105VNH	ABC transporter solute-binding protein
K04M5_11690	ENOG4105XZD	Fe-S protein
K04M5_11710	ENOG4105CGH	5'-nucleotidase
K04M5_11730	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
K04M5_11740	ENOG4105EB3	Histidine kinase
K04M5_11750	ENOG4105ETX	regulatoR
K04M5_11770	ENOG4105CFI	type iii restriction protein res subunit
K04M5_11780	ENOG4105I08	Pseudouridine synthase
K04M5_11790	ENOG4105C2C	drug resistance transporter, Bcr CflA
K04M5_11810	ENOG4105CGD	Nad-dependent epimerase dehydratase
K04M5_11820	ENOG4107QI1	Mate efflux family protein
K04M5_11860	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
K04M5_11870	ENOG41067SE	Tetr family transcriptional regulator
K04M5_11880	ENOG4107QPN	acyl-Coa dehydrogenase
K04M5_11890	ENOG4105RKW	reductase (By
K04M5_11900	ENOG4105D0C	transport protein
K04M5_11910	ENOG41090BQ	Glutaredoxin
K04M5_11940	ENOG4106KNT	transcriptional regulator
K04M5_11950	ENOG4105DY8	decarboxylase
K04M5_11970	ENOG4105DWU	Membrane
K04M5_12030	ENOG4105BZU	Histidine kinase
K04M5_12050	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
K04M5_12060	ENOG4105BZC	d-serine deaminase
K04M5_12070	ENOG4108JJ8	(ABC) transporter
K04M5_12080	ENOG4108JJ9	ABC, transporter
K04M5_12090	ENOG4105C3M	thioredoxin reductase
K04M5_12130	ENOG4105BZU	Histidine kinase
K04M5_12140	ENOG4105C8P	)-transporter
K04M5_12150	ENOG4107GZ4	SanA protein
K04M5_12160	ENOG4107R1I	NAD-dependent malic enzyme
K04M5_12170	ENOG4105CQ7	ATP-dependent helicase
K04M5_12200	ENOG4105C8V	SAICAR synthetase
K04M5_12240	ENOG4105CDV	Ompa motb domain protein
K04M5_12270	ENOG4105CQB	FAD linked oxidase domain protein
K04M5_12300	ENOG4105C84	Histidine ammonia-lyase
K04M5_12320	ENOG41088SP	formiminoglutamate hydrolase
K04M5_12330	ENOG4105CI2	imidazolone-5-propionate hydrolase
K04M5_12340	ENOG4105CZE	histidine utilization repressor
K04M5_12370	ENOG4105C22	threonyL-tRNA synthetase
K04M5_12380	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
K04M5_12390	ENOG41082NX	50s ribosomal protein l35
K04M5_12400	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
K04M5_12410	ENOG4105K8R	UPF0145 protein
K04M5_12480	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
K04M5_12490	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
K04M5_12510	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
K04M5_12530	ENOG4105FQ6	thiopurine methyltransferase
K04M5_12540	ENOG4108HH9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
K04M5_12550	ENOG4107T42	This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis (By similarity)
K04M5_12560	ENOG41067MG	lrgb family
K04M5_12570	ENOG4105VAW	lrga family
K04M5_12580	ENOG4105CJB	Exodeoxyribonuclease I
K04M5_12700	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
K04M5_12760	ENOG4106CVF	DNA replication protein
K04M5_13050	ENOG4108ETY	sodium dicarboxylate symporter
K04M5_13060	ENOG4105K4T	epimerase
K04M5_13070	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
K04M5_13080	ENOG4108UHF	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
K04M5_13120	ENOG4107UI5	Transforms N(2)-succinylglutamate into succinate and glutamate (By similarity)
K04M5_13130	ENOG4108IU2	vtamin B12-transporter permease
K04M5_13140	ENOG41080WI	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system (By similarity)
K04M5_13180	ENOG4105F04	LysR family Transcriptional regulator
K04M5_13200	ENOG4108VKG	metal-dependent hydrolase
K04M5_13210	ENOG4105EBA	Specifically methylates the adenine in position 1618 of 23S rRNA (By similarity)
K04M5_13270	ENOG4105CTU	Proline racemase
K04M5_13300	ENOG4105CIF	Ornithine Cyclodeaminase
K04M5_13310	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
K04M5_13320	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
K04M5_13330	ENOG4105F38	ABC transporter, permease
K04M5_13340	ENOG4105D38	putrescine abc transporter
K04M5_13360	ENOG4107MM9	BNR Asp-box repeat-containing protein
K04M5_13380	ENOG4108JQ7	(ABC) transporter
K04M5_13390	ENOG4105C3U	ABC transporter
K04M5_13400	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
K04M5_13410	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
K04M5_13420	ENOG4107QSI	ABC, transporter
K04M5_13430	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
K04M5_13440	ENOG4105E6K	4-Hydroxyphenylpyruvate dioxygenase
K04M5_13450	ENOG4105F1J	Homogentisate 1,2-dioxygenase
K04M5_13470	ENOG4108RXX	maleylacetoacetate isomerase
K04M5_13570	ENOG4105VTN	Protein of unknown function (DUF1311)
K04M5_13620	ENOG4105KK4	UPF0060 membrane protein
K04M5_13650	ENOG4107S6Z	Na H antiporter
K04M5_13660	ENOG4105CFQ	glutamine synthetase
K04M5_13670	ENOG4108Z86	Glutamine amidotransferase
K04M5_13680	ENOG4107VRI	Transcriptional regulator
K04M5_13690	ENOG4105C26	Dehydrogenase
K04M5_13700	ENOG4105CJP	fad dependent oxidoreductase
K04M5_13720	ENOG4105DWY	Agmatine deiminase
K04M5_13730	ENOG4105C26	Dehydrogenase
K04M5_13740	ENOG4108JPW	Aminotransferase
K04M5_13750	ENOG4105BZU	Histidine kinase
K04M5_13770	ENOG4108ZT1	Transcriptional regulator
K04M5_13780	ENOG4105MSB	protein, conserved in bacteria
K04M5_13830	ENOG4105BZU	Histidine kinase
K04M5_13840	ENOG4105BZU	Histidine kinase
K04M5_13860	ENOG41090FY	type IV pilus biogenesis stability protein PilW
K04M5_13870	ENOG4105CVG	Homoserine O-transsuccinylase
K04M5_13900	ENOG4105D1S	lipid A biosynthesis
K04M5_13920	ENOG4107TII	Recombinase
K04M5_14170	ENOG4105CTD	carboxy-peptidase
K04M5_14180	ENOG410829K	Lysine exporter protein (Lyse ygga)
K04M5_14200	ENOG4105BZG	amino acid carrier protein
K04M5_14250	ENOG4105E0M	Sulfatase
K04M5_14260	ENOG4105GIJ	Glycine betaine
K04M5_14270	ENOG4108HQS	Glycine betaine
K04M5_14280	ENOG4108IJ7	Glycine betaine
K04M5_14310	ENOG4105C94	Transporter
K04M5_14320	ENOG4108Z24	l-2,4-diaminobutyric acid acetyltransferase
K04M5_14330	ENOG4108JPW	Aminotransferase
K04M5_14340	ENOG4108Z6K	Catalyzes the circularization of gamma-N-acetyl- alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6- tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant (By similarity)
K04M5_14350	ENOG4105CZK	Aspartate kinase
K04M5_14360	ENOG4105ENH	Sulfatase
K04M5_14390	ENOG4105C4X	radical SAM domain protein
K04M5_14420	ENOG4105ENH	Sulfatase
K04M5_14430	ENOG4107QRH	Arylsulfatase (Ec 3.1.6.1)
K04M5_14450	ENOG4108JJA	ABC, transporter
K04M5_14470	ENOG4105DFG	type I secretion outer membrane protein
K04M5_14500	ENOG4105E98	transcriptional regulator DeoR family
K04M5_14510	ENOG4105D9R	oxidoreductase
K04M5_14520	ENOG41090KN	UPF0303 protein
K04M5_14530	ENOG4105BZU	Histidine kinase
K04M5_14570	ENOG4105C8P	)-transporter
K04M5_14590	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
K04M5_14600	ENOG4105BZU	Histidine kinase
K04M5_14610	ENOG4105CPI	Metal Dependent Phosphohydrolase
K04M5_14620	ENOG410829K	Lysine exporter protein (Lyse ygga)
K04M5_14630	ENOG4105G0K	glycine radical enzyme YjjI family
K04M5_14640	ENOG41076CZ	activating enzyme
K04M5_14660	ENOG4105EE5	Membrane protein terC
K04M5_14680	ENOG4105DHT	Metal Dependent Phosphohydrolase
K04M5_14700	ENOG4105E0U	tyrosine-specific transport protein
K04M5_14710	ENOG4105CPI	Metal Dependent Phosphohydrolase
K04M5_14730	ENOG4105E0A	ABC, transporter
K04M5_14740	ENOG4105J76	Periplasmic binding protein
K04M5_14750	ENOG4105S6R	Iron-hydroxamate transporter permease subunit
K04M5_14760	ENOG4105E0K	tonB-dependent siderophore receptor
K04M5_14780	ENOG4105BZ1	(ABC) transporter
K04M5_14790	ENOG4105BZ1	(ABC) transporter
K04M5_14800	ENOG4108VAU	general secretion pathway protein G
K04M5_14820	ENOG4105CR8	Transcriptional regulator
K04M5_14870	ENOG4105CFG	Acts as a chaperone (By similarity)
K04M5_14880	ENOG4105CFG	Acts as a chaperone (By similarity)
K04M5_14980	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
K04M5_14990	ENOG4105CQ7	ATP-dependent helicase
K04M5_15020	ENOG4105C94	Transporter
K04M5_15050	ENOG4107R8N	Glycosyl transferase, family 2
K04M5_15060	ENOG4105CPK	Glycosyl transferase (Group 1
K04M5_15120	ENOG4107TYR	Glycosyl Transferase
K04M5_15130	ENOG4107SBE	Glycosyl transferase (Group 1
K04M5_15140	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
K04M5_15170	ENOG4107V1M	polysaccharide export protein
K04M5_15190	ENOG41082AN	stage II sporulation protein
K04M5_15230	ENOG4107QI1	Mate efflux family protein
K04M5_15240	ENOG4108R6K	riboflavin synthase, subunit alpha
K04M5_15260	ENOG4105FGM	Fructosamine kinase
K04M5_15280	ENOG4105BZU	Histidine kinase
K04M5_15300	ENOG4107TT5	NLP P60 protein
K04M5_15370	ENOG4106IUH	DTW domain containing protein
K04M5_15380	ENOG4105EZX	Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P (By similarity)
K04M5_15400	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
K04M5_15410	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
K04M5_15420	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
K04M5_15450	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
K04M5_15460	ENOG4105BZU	Histidine kinase
K04M5_15470	ENOG4105C5H	ABC transporter
K04M5_15490	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
K04M5_15530	ENOG4109039	Involved in the biogenesis of TorA. Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor (By similarity)
K04M5_15550	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
K04M5_15560	ENOG4105QAX	Iron-sulfur
K04M5_15630	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
K04M5_15640	ENOG4107RUE	extracellular solute-binding protein family 1
K04M5_15650	ENOG4107RUE	extracellular solute-binding protein family 1
K04M5_15660	ENOG4105D38	putrescine abc transporter
K04M5_15670	ENOG4105F38	ABC transporter, permease
K04M5_15680	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
K04M5_15720	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
K04M5_15730	ENOG4105Q9Y	Universal stress protein
K04M5_15740	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
K04M5_15770	ENOG4105C59	p-type ATPase
K04M5_15790	ENOG4105D6P	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex (By similarity)
K04M5_15820	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
K04M5_15880	ENOG4108R9Q	Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle. Prevents early segregation of duplicated Ter macrodomains during cell division. Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain (By similarity)
K04M5_15890	ENOG4105DAN	ATP-dependent protease
K04M5_15900	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
K04M5_15930	ENOG4105C5H	ABC transporter
K04M5_15950	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
K04M5_15960	ENOG4108T7E	Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ (By similarity)
K04M5_15970	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
K04M5_15980	ENOG4105C7I	Dehydrogenase
K04M5_15990	ENOG4105CD8	aminopeptidase N
K04M5_16010	ENOG4105CN1	protease
K04M5_16020	ENOG41073DY	may be a structural element that influences the osmotic activation of ProP at a post-translational level (By similarity)
K04M5_16030	ENOG4108ZGC	gaf domain protein
K04M5_16040	ENOG4105BZ1	(ABC) transporter
K04M5_16050	ENOG4105H2K	paraquat-inducible protein a
K04M5_16060	ENOG4105DY2	Paraquat-inducible protein b
K04M5_16070	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
K04M5_16110	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
K04M5_16120	ENOG4108VPT	UPF0234 protein
K04M5_16140	ENOG4107QXX	ABC transporter
K04M5_16160	ENOG4105EZ7	amino acid ABC transporter
K04M5_16170	ENOG4105DRP	amino acid AbC transporter
K04M5_16180	ENOG4105CDA	abc transporter atp-binding protein
K04M5_16190	ENOG4108MN8	Membrane
K04M5_16210	ENOG4108Z0T	Part of a sulfur-relay system (By similarity)
K04M5_16220	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
K04M5_16230	ENOG4105C8Q	Methyl-accepting chemotaxis
K04M5_16240	ENOG4105DR4	Methyltransferase
K04M5_16270	ENOG4105KCK	Peptidoglycan-associated lipoprotein
K04M5_16300	ENOG4105CDV	Ompa motb domain protein
K04M5_16320	ENOG4105BZU	Histidine kinase
K04M5_16330	ENOG4107HP6	Transcriptional regulator
K04M5_16350	ENOG4105CV8	reductase
K04M5_16360	ENOG4105HEI	LysR family (Transcriptional regulator
K04M5_16380	ENOG4105HEI	LysR family (Transcriptional regulator
K04M5_16390	ENOG4105F27	Major Facilitator
K04M5_16420	ENOG41063TF	transcriptional regulator (AraC
K04M5_16430	ENOG4108W2Y	isochorismatase
K04M5_16440	ENOG4106PMH	Extracellular solute-binding protein family 3
K04M5_16460	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
K04M5_16470	ENOG4105C3R	Methionine synthase
K04M5_16480	ENOG4105CDA	abc transporter atp-binding protein
K04M5_16490	ENOG4105EAD	ABC transporter
K04M5_16500	ENOG4106PMH	Extracellular solute-binding protein family 3
K04M5_16540	ENOG4105CC0	LysR family Transcriptional regulator
K04M5_16570	ENOG4105HEI	LysR family (Transcriptional regulator
K04M5_16590	ENOG41090KR	LysR family transcriptional Regulator
K04M5_16620	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
K04M5_16630	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
K04M5_16640	ENOG410667J	hydrolase
K04M5_16660	ENOG4105NDH	peptidase s1 and s6 chymotrypsin hap
K04M5_16680	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
K04M5_16690	ENOG4105C7F	AcnD-accessory protein PrpF
K04M5_16700	ENOG4108I0Z	Aconitate hydratase
K04M5_16710	ENOG4105BZN	citrate synthase
K04M5_16720	ENOG4105CR4	methylisocitrate lyase
K04M5_16790	ENOG4105EJ9	Membrane
K04M5_17010	ENOG4105E7U	AraC family transcriptional regulator
K04M5_17150	ENOG41066XE	Type III export protein
K04M5_17210	ENOG4108KB1	transcriptional regulator, arac family
K04M5_17250	ENOG4105C26	Dehydrogenase
K04M5_17260	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
K04M5_17290	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
K04M5_17300	ENOG4108Q79	6-phosphogluconolactonase (EC 3.1.1.31)
K04M5_17310	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
K04M5_17340	ENOG4106YYS	transcriptional regulatory protein
K04M5_17350	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
K04M5_17380	ENOG4107KET	secretion protein, HlyD family
K04M5_17410	ENOG4105DUM	transcriptional regulator, lysR family
K04M5_17440	ENOG4107XGF	functions in a salvage pathway. Uses pyridoxamine (By similarity)
K04M5_17470	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
K04M5_17570	ENOG4106YYS	transcriptional regulatory protein
K04M5_17580	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
K04M5_17610	ENOG4107KET	secretion protein, HlyD family
K04M5_17640	ENOG4105DUM	transcriptional regulator, lysR family
K04M5_17670	ENOG4107XGF	functions in a salvage pathway. Uses pyridoxamine (By similarity)
K04M5_17680	ENOG4105CEB	Aspartate aminotransferase
K04M5_17690	ENOG4105D0C	transport protein
K04M5_17710	ENOG4105Y49	secretion protein, HlyD family
K04M5_17760	ENOG4105EBR	Carboxylesterase
K04M5_17790	ENOG4105CFU	surface antigen
K04M5_17800	ENOG41090VV	Protein of unknown function (DUF2846)
K04M5_17810	ENOG4105N14	lysine exporter protein LysE YggA
K04M5_17830	ENOG4105KCV	RNA signal recognition particle 4.5S RNA
K04M5_17870	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
K04M5_17880	ENOG4105KNA	-acetyltransferase
K04M5_17890	ENOG4108UW5	maltose o-acetyltransferase
K04M5_18020	ENOG4105EWC	Purine nucleoside phosphorylase
K04M5_18190	ENOG4108R4U	Hnh endonuclease
K04M5_18350	ENOG4105BZU	Histidine kinase
K04M5_18370	ENOG4105D0C	transport protein
K04M5_18380	ENOG4105CVK	Glutamate decarboxylase
K04M5_18390	ENOG4107QUT	magnesium and cobalt transport protein CorA
K04M5_18410	ENOG4105EWV	Sodium calcium exchanger membrane region
K04M5_18420	ENOG4105EWV	Sodium calcium exchanger membrane region
K04M5_18450	ENOG4108MI0	Resistance protein
K04M5_18460	ENOG4105J12	Multidrug resistance protein mdtN
K04M5_18480	ENOG4107QHE	Choloylglycine hydrolase
K04M5_18500	ENOG4105D0C	transport protein
K04M5_18510	ENOG4107SUZ	Sodium/hydrogen exchanger family
K04M5_18550	ENOG4107KGK	dmso reductase anchor subunit
K04M5_18560	ENOG4105QAX	Iron-sulfur
K04M5_18570	ENOG4107QY8	reductase
K04M5_18580	ENOG4108NEM	leader-binding protein dmsD
K04M5_18590	ENOG4105N1P	Ferredoxin-type protein
K04M5_18600	ENOG4105BZU	Histidine kinase
K04M5_18690	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
K04M5_18740	ENOG4105R3P	Inner membrane protein yagU
K04M5_18750	ENOG4105BZU	Histidine kinase
K04M5_18760	ENOG4108WQH	regulatoR
K04M5_18830	ENOG4105UYK	outer membrane protein a
K04M5_18930	ENOG4105BZU	Histidine kinase
K04M5_18940	ENOG4108WQH	regulatoR
K04M5_18970	ENOG4108YX2	DNA-binding protein
K04M5_19070	ENOG4105D3W	isochorismatase
K04M5_19200	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
K04M5_19260	ENOG4105D9U	N-acetyltransferase
K04M5_19280	ENOG4106K28	UPF0283 membrane protein
K04M5_19290	ENOG4105CM6	amino acid regulated cytosolic protein
K04M5_19320	ENOG4105CRQ	synthase (Component I)
K04M5_19350	ENOG4105P8F	nudix hydrolase
K04M5_19360	ENOG4105C44	Serine transporter
K04M5_19370	ENOG4105EJQ	L-serine dehydratase
K04M5_19380	ENOG4105BZU	Histidine kinase
K04M5_19400	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
K04M5_19410	ENOG4105C8Q	Methyl-accepting chemotaxis
K04M5_19420	ENOG4105C5S	asparaginyl-tRNA synthetase
K04M5_19440	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
K04M5_19470	ENOG4105CGF	Aromatic amino acid aminotransferase
K04M5_19510	ENOG4105C8Q	Methyl-accepting chemotaxis
K04M5_19520	ENOG4105C94	Transporter
K04M5_19560	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
K04M5_19580	ENOG4105CH5	extracellular solute-binding protein, family 7
K04M5_19610	ENOG4105C5X	domain protein
K04M5_19620	ENOG4105EAQ	(twin-arginine translocation) pathway signal
K04M5_19630	ENOG4105DIT	ErfK YbiS YcfS YnhG family protein
K04M5_19680	ENOG4107T1C	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity)
K04M5_19700	ENOG4108DMF	Cytochrome C biogenesis protein
K04M5_19710	ENOG4107QX9	Thiol disulfide interChange protein
K04M5_19720	ENOG4105DA4	cytochrome c-type biogenesis protein
K04M5_19730	ENOG4105DVI	reductase, NrfD
K04M5_19740	ENOG4105D3S	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
K04M5_19760	ENOG4105EAU	Plays a role in nitrite reduction (By similarity)
K04M5_19790	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
K04M5_19800	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
K04M5_19810	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
K04M5_19820	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
K04M5_19870	ENOG4105D3D	Catalyzes the decarboxylation of carboxynorspermidine and carboxyspermidine (By similarity)
K04M5_19950	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
K04M5_19960	ENOG4105WH1	Two component transcriptional regulator luxr family
K04M5_19970	ENOG4105CQ2	DNA polymerase
K04M5_20000	ENOG4108W5H	UPF0263 protein
K04M5_20010	ENOG4105FE9	pseudouridine synthase
K04M5_20030	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
K04M5_20040	ENOG4105DB7	PHP domain protein
K04M5_20060	ENOG4105CRQ	synthase (Component I)
K04M5_20070	ENOG4105DDQ	anthranilate synthase
K04M5_20080	ENOG4108I0Q	anthranilate phosphoribosyltransferase
K04M5_20090	ENOG4105DK0	Indole-3-glycerol phosphate synthase
K04M5_20100	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
K04M5_20110	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
K04M5_20120	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
K04M5_20130	ENOG4105CEY	Amp-dependent synthetase and ligase
K04M5_20140	ENOG4105CK2	sodium dicarboxylate symporter
K04M5_20160	ENOG4105BZU	Histidine kinase
K04M5_20180	ENOG4107835	probably involved in intracellular septation (By similarity)
K04M5_20190	ENOG4105NAU	thioesterase Superfamily protein
K04M5_20200	ENOG4105K9H	YciI-like protein
K04M5_20220	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
K04M5_20230	ENOG4105DZ2	Transcriptional regulator
K04M5_20270	ENOG4105CCT	upf0313 protein
K04M5_20310	ENOG4105SA9	Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
K04M5_20330	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
K04M5_20340	ENOG41062D9	Histidine kinase
K04M5_20370	ENOG4105JQN	Transcriptional regulator
K04M5_20380	ENOG4105J12	Multidrug resistance protein mdtN
K04M5_20400	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
K04M5_20440	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
K04M5_20450	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
K04M5_20460	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
K04M5_20480	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
K04M5_20510	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
K04M5_20530	ENOG4105N6Y	Thioredoxin
K04M5_20540	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
K04M5_20560	ENOG4108ZXC	Two component transcriptional regulator, luxr family
K04M5_20570	ENOG4106AFQ	Histidine kinase
K04M5_20580	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
K04M5_20590	ENOG4106WHD	Tetrathionate reductase
K04M5_20600	ENOG4105DB1	molybdopterin oxidoreductase
K04M5_20620	ENOG4105NQN	cytochrome C
K04M5_20630	ENOG4105F1S	paraquat-inducible protein a
K04M5_20640	ENOG4105DY2	Paraquat-inducible protein b
K04M5_20680	ENOG4108J59	Extracellular solute-binding protein, family 5
K04M5_20690	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
K04M5_20700	ENOG4105CFV	Tetratricopeptide repeat protein
K04M5_20710	ENOG4105Q4A	inner membrane protein yciS
K04M5_20720	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
K04M5_20730	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
K04M5_20740	ENOG4105CAT	Cytidine monophosphate kinase
K04M5_20750	ENOG4105ERU	peptidase
K04M5_20760	ENOG4105UBK	short-chain dehydrogenase reductase
K04M5_20790	ENOG4105C0B	DNA polymerase III (alpha subunit)
K04M5_20800	ENOG4107R88	Chemotaxis protein (CheV)
K04M5_20810	ENOG4105DAG	ROK family
K04M5_20820	ENOG4105CA9	Pyruvate kinase
K04M5_20830	ENOG4108NRW	Phospholipase, patatin family
K04M5_20860	ENOG4105C8J	)-transporter
K04M5_20890	ENOG4105CI1	PTS System
K04M5_20900	ENOG4105F8V	Hydrolase, tatD family
K04M5_20910	ENOG4107QRG	dna polymerase iii
K04M5_20920	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
K04M5_20930	ENOG4105HHA	aminodeoxychorismate lyase
K04M5_20950	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
K04M5_20960	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
K04M5_20970	ENOG4105CHR	reductase
K04M5_20980	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
K04M5_20990	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
K04M5_21000	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
K04M5_21010	ENOG4105VGS	50s ribosomal protein l32
K04M5_21020	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
K04M5_21030	ENOG4108UHJ	MAF-like protein
K04M5_21040	ENOG4105EI2	Pseudouridine synthase
K04M5_21050	ENOG4105C03	ribonuclease
K04M5_21060	ENOG4105CHH	sulfate transporter
K04M5_21080	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
K04M5_21100	ENOG4105DBI	uridine monophosphokinase
K04M5_21110	ENOG4105D1F	ATP-binding protein
K04M5_21120	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
K04M5_21160	ENOG4105C05	Multifunctional regulator of fatty acid metabolism (By similarity)
K04M5_21180	ENOG410635M	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
K04M5_21190	ENOG4106RHG	Yeca family
K04M5_21200	ENOG4105FBT	Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity)
K04M5_21210	ENOG4105BZU	Histidine kinase
K04M5_21220	ENOG4107R28	alpha amylase, catalytic region
K04M5_21230	ENOG4108JJB	ABC transporter
K04M5_21240	ENOG4105C7J	ABC transporter, permease
K04M5_21260	ENOG4105PQ6	UPF0208 membrane protein
K04M5_21270	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
K04M5_21280	ENOG4108DNC	Involved in acetate metabolism (By similarity)
K04M5_21300	ENOG4105CHF	Glutathione S-transferase
K04M5_21310	ENOG4108JQ7	(ABC) transporter
K04M5_21320	ENOG4105C3U	ABC transporter
K04M5_21330	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
K04M5_21340	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
K04M5_21350	ENOG4107QSI	ABC, transporter
K04M5_21360	ENOG4108ZAF	Molybdopterin
K04M5_21370	ENOG4105M00	molybdopterin converting factor, subunit 1
K04M5_21380	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
K04M5_21390	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
K04M5_21400	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
K04M5_21410	ENOG4105CHW	UPF0052 protein
K04M5_21430	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
K04M5_21440	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
K04M5_21460	ENOG4105C6N	Formate acetyltransferase
K04M5_21470	ENOG4105DGN	Electron transport complex
K04M5_21480	ENOG4108R3D	Electron transport complex
K04M5_21500	ENOG4105D6A	Electron transport complex
K04M5_21510	ENOG4108UQQ	Electron transport complex
K04M5_21520	ENOG4105DZB	Electron transport complex
K04M5_21530	ENOG4105CSM	endonuclease III
K04M5_21540	ENOG4108UYE	Lactoylglutathione lyase
K04M5_21550	ENOG4106WH9	Protein of unknown function (DUF2753)
K04M5_21560	ENOG4105EIY	sodium-type flagellar protein motY
K04M5_21570	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
K04M5_21580	ENOG4105D3Y	Na H antiporter
K04M5_21620	ENOG4105M2J	Glutaredoxin
K04M5_21630	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
K04M5_21660	ENOG4108EKI	Dehydrogenase
K04M5_21670	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
K04M5_21680	ENOG4105EYW	Ion transport protein
K04M5_21690	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
K04M5_21700	ENOG4105DFD	Na H antiporter
K04M5_21730	ENOG4106V8H	Nucleoid-associated protein
K04M5_21740	ENOG4105YDX	UPF0352 protein
K04M5_21750	ENOG4105E68	Sulfatase
K04M5_21770	ENOG4105DGU	Histone deacetylase
K04M5_21780	ENOG4108RU0	short-chain dehydrogenase reductase
K04M5_21800	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
K04M5_21810	ENOG41069NU	Nitroreductase
K04M5_21830	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
K04M5_21840	ENOG4105D07	Signal peptide peptidase, SppA
K04M5_21850	ENOG4105HDK	L-asparaginase
K04M5_21860	ENOG4105VUT	cytoplasmic protein
K04M5_21880	ENOG4105E0X	reductase
K04M5_21890	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
K04M5_21900	ENOG4105DSB	aldose 1-epimerase
K04M5_21910	ENOG4107SDU	Methyl-accepting chemotaxis
K04M5_21920	ENOG4105DHI	Methyltransferase
K04M5_21950	ENOG4105G6Z	alkaline phosphatase
K04M5_21980	ENOG41067V3	Antibiotic biosynthesis monooxygenase
K04M5_22000	ENOG4108ZZ3	UPF0260 protein
K04M5_22010	ENOG4105Y3U	Transglycosylase-associated protein
K04M5_22020	ENOG4105KRS	Proteinase inhibitor
K04M5_22030	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
K04M5_22040	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
K04M5_22050	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
K04M5_22060	ENOG4107QMP	dna polymerase iii subunits gamma and tau
K04M5_22070	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
K04M5_22080	ENOG4105WD1	Membrane
K04M5_22100	ENOG4105I93	response regulator
K04M5_22110	ENOG4105EJC	lysr family transcriptional regulator
K04M5_22120	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
K04M5_22130	ENOG4105E96	Colicin v production protein
K04M5_22140	ENOG4108S3P	Sporulation domain protein
K04M5_22150	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
K04M5_22160	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
K04M5_22170	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
K04M5_22190	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
K04M5_22200	ENOG4105CJ0	Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate (By similarity)
K04M5_22210	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
K04M5_22220	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
K04M5_22230	ENOG4105Q8W	reductase
K04M5_22240	ENOG4105MH2	YfcL protein
K04M5_22250	ENOG4108BPE	-transporting atpase
K04M5_22260	ENOG4105EN6	Membrane
K04M5_22270	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
K04M5_22280	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
K04M5_22290	ENOG4108DG9	Smr protein MutS2
K04M5_22300	ENOG4108BY2	phosphohistidine phosphatase
K04M5_22310	ENOG4107QXK	peptidase
K04M5_22330	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
K04M5_22340	ENOG4105CHU	acetyl-coa acetyltransferase
K04M5_22380	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
K04M5_22390	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
K04M5_22420	ENOG410903C	(LipO)protein
K04M5_22430	ENOG4105KWW	Biogenesis protein
K04M5_22440	ENOG4108M1T	Cytochrome c-type biogenesis protein
K04M5_22450	ENOG4107QX9	Thiol disulfide interChange protein
K04M5_22460	ENOG4105DA4	cytochrome c-type biogenesis protein
K04M5_22470	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
K04M5_22480	ENOG4105X3C	heme exporter protein
K04M5_22490	ENOG41060IM	Heme exporter protein
K04M5_22500	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
K04M5_22510	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
K04M5_22530	ENOG4108V3W	Chemotaxis protein, CheW
K04M5_22550	ENOG4107QJE	Chromosome Partitioning Protein
K04M5_22560	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
K04M5_22570	ENOG4105CBS	Chea signal transduction histidine kinase
K04M5_22580	ENOG4108KCC	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity)
K04M5_22590	ENOG4108VYJ	response regulator receiver protein
K04M5_22600	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
K04M5_22610	ENOG4107R21	site-determining protein
K04M5_22620	ENOG4105FZW	flagellar biosynthesis regulator FlhF
K04M5_22630	ENOG4105D7B	Flagellar biosynthesis protein flha
K04M5_22640	ENOG4105D00	flagellar biosynthetic protein flhB
K04M5_22650	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
K04M5_22660	ENOG4105VS8	Flagellar biosynthetic protein fliq
K04M5_22670	ENOG4105CN7	Flagellar biosynthetic protein FliP
K04M5_22680	ENOG4105VTB	flagellar biosynthesis protein fliO
K04M5_22690	ENOG4105DD5	Flagellar motor switch protein
K04M5_22700	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
K04M5_22750	ENOG4108JIR	Flagellum-specific ATP synthase
K04M5_22770	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
K04M5_22780	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
K04M5_22790	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
K04M5_22800	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
K04M5_22810	ENOG4105BZU	Histidine kinase
K04M5_22820	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
K04M5_22830	ENOG4105MQ3	flagellar protein FliS
K04M5_22850	ENOG4107BRV	flagellar capping protein
K04M5_22860	ENOG41063QE	flagellar protein FlaG
K04M5_22870	ENOG4105I03	Flagellin
K04M5_22880	ENOG4105I03	Flagellin
K04M5_22890	ENOG4105I03	Flagellin
K04M5_22900	ENOG4105EZR	dyp-type peroxidase family protein
K04M5_22910	ENOG4105QZU	Inner membrane protein YfeZ
K04M5_22950	ENOG4105KUZ	arsenate reductase
K04M5_22960	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
K04M5_22990	ENOG4107EG0	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
K04M5_23020	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
K04M5_23070	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
K04M5_23100	ENOG4108JJA	ABC, transporter
K04M5_23110	ENOG4108MBX	Secretion Protein
K04M5_23150	ENOG4108NV9	Glycosyl Transferase
K04M5_23200	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
K04M5_23220	ENOG4105C4R	Atp-dependent dna helicase
K04M5_23250	ENOG4105BZU	Histidine kinase
K04M5_23260	ENOG41090WB	Transposase is3 is911
K04M5_23290	ENOG4105VEQ	Cold shock protein
K04M5_23340	ENOG4105VEQ	Cold shock protein
K04M5_23350	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
K04M5_23360	ENOG4107QJR	hflk protein
K04M5_23380	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
K04M5_23390	ENOG4107QM5	aconitate hydratase
K04M5_23400	ENOG4105VEQ	Cold shock protein
K04M5_23430	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
K04M5_23460	ENOG4105ERG	peptidase m48, ste24p
K04M5_23470	ENOG4105K89	arsenate reductase
K04M5_23480	ENOG4105CS1	NAD(P)H quinone oxidoreductase
K04M5_23510	ENOG4105C2W	permease
K04M5_23530	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
K04M5_23540	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
K04M5_23560	ENOG4105E7A	Glutamine amidotransferase
K04M5_23570	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
K04M5_23580	ENOG4107QPN	acyl-Coa dehydrogenase
K04M5_23640	ENOG4108JDX	DNA polymerase iii, epsilon subunit
K04M5_23650	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
K04M5_23660	ENOG4105D1A	Methyltransferase
K04M5_23670	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
K04M5_23680	ENOG4105E9H	Lytic Murein transglycosylase
K04M5_23700	ENOG4107NA1	Endonuclease Exonuclease phosphatase
K04M5_23710	ENOG4108YZA	Nitrogen regulatory protein pii
K04M5_23720	ENOG4105N7H	Cytochrome
K04M5_23730	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
K04M5_23740	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
K04M5_23750	ENOG4105C0B	DNA polymerase III (alpha subunit)
K04M5_23760	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
K04M5_23770	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
K04M5_23780	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
K04M5_23790	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
K04M5_23800	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
K04M5_23810	ENOG4108RFI	Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm (By similarity)
K04M5_23830	ENOG4105DZP	Membrane-associated zinc metalloprotease
K04M5_23840	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
K04M5_23850	ENOG4105KNE	Phosphatidate cytidylyltransferase
K04M5_23860	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
K04M5_23870	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
K04M5_23880	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
K04M5_23890	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
K04M5_23900	ENOG4105CE9	30S ribosomal protein S2
K04M5_23910	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
K04M5_23920	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
K04M5_23930	ENOG4108T8E	UPF0325 protein
K04M5_23940	ENOG4105DR9	pseudouridine synthase
K04M5_23950	ENOG4105WP7	tRNA pseudouridine synthase C
K04M5_24000	ENOG4108UPT	UPF0178 protein
K04M5_24010	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
K04M5_24020	ENOG4107VBM	3-beta hydroxysteroid dehydrogenase isomerase
K04M5_24070	ENOG4105CFC	Transporter
K04M5_24080	ENOG4105NRA	50s ribosomal protein l31 type b
K04M5_24090	ENOG4108R96	Methyltransferase, YaeB family
K04M5_24100	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
K04M5_24120	ENOG4105W1I	UPF0253 protein
K04M5_24140	ENOG4105C8J	)-transporter
K04M5_24170	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
K04M5_24180	ENOG4105C9U	ATP-dependent DNA helicase RecQ
K04M5_24230	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
K04M5_24330	ENOG4108ZXE	
K04M5_24390	ENOG4105CHH	sulfate transporter
K04M5_24410	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
K04M5_24510	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
K04M5_24530	ENOG4105BZU	Histidine kinase
K04M5_24550	ENOG4105CJ2	(LipO)protein
K04M5_24560	ENOG4105D26	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway (By similarity)
K04M5_24570	ENOG4108IUB	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
K04M5_24580	ENOG4105F5D	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
K04M5_24590	ENOG4106I92	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
K04M5_24600	ENOG4108J5C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
K04M5_24610	ENOG4105DWQ	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
K04M5_24620	ENOG4105M85	Bola protein
K04M5_24630	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
K04M5_24640	ENOG4105IEY	(LipO)protein
K04M5_24650	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
K04M5_24680	ENOG4105K6V	RNA polymerase
K04M5_24720	ENOG4108JZF	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
K04M5_24730	ENOG4107S0N	DJ-1 family
K04M5_24740	ENOG4105C9B	Cysteine desulfurase
K04M5_24750	ENOG4105BZU	Histidine kinase
K04M5_24760	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
K04M5_24770	ENOG4105CUZ	uba thif-type nad fad binding protein
K04M5_24780	ENOG4105CA3	membrane-bound lytic murein transglycosylase
K04M5_24800	ENOG4107QZM	n-acetylglutamate synthase
K04M5_24820	ENOG4107QYX	exodeoxyribonuclease v alpha
K04M5_24830	ENOG4107QKA	exodeoxyribonuclease V beta
K04M5_24840	ENOG4105DSY	exodeoxyribonuclease V, gamma
K04M5_24850	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
K04M5_24940	ENOG4105DVF	Cytosine-specific methyltransferase
K04M5_24960	ENOG4105E68	Sulfatase
K04M5_24980	ENOG4105EVZ	LysR family transcriptional regulator
K04M5_24990	ENOG4105X2V	dna damage-inducible protein
K04M5_25020	ENOG4105EJ3	Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA (By similarity)
K04M5_25030	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
K04M5_25040	ENOG4105CXY	transporter
K04M5_25050	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
K04M5_25060	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
K04M5_25070	ENOG4105E98	transcriptional regulator DeoR family
K04M5_25080	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
K04M5_25090	ENOG4107RX3	Mg2 transporter protein cora family protein
K04M5_25130	ENOG4105CQ4	Transcriptional regulator
K04M5_25140	ENOG41064T2	transcriptional regulator, lysR family
K04M5_25160	ENOG41086KC	Transcriptional regulator
K04M5_25220	ENOG4108IQE	Amp-dependent synthetase and ligase
K04M5_25240	ENOG4105ETT	transcriptional Regulator, LysR family
K04M5_25250	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
K04M5_25260	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
K04M5_25280	ENOG4105EAC	phosphoserine phosphatase
K04M5_25300	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
K04M5_25310	ENOG4105CZG	Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity)
K04M5_25320	ENOG4105CMW	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity)
K04M5_25330	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
K04M5_25340	ENOG4105D9N	nucleoside
K04M5_25350	ENOG4105EYA	deoxyribonuclease
K04M5_25370	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
K04M5_25410	ENOG4108YYD	acetyltransferase
K04M5_25420	ENOG4105XPQ	lipid carrier protein
K04M5_25430	ENOG4105BZU	Histidine kinase
K04M5_25440	ENOG4105CFP	Peptidase U32
K04M5_25450	ENOG4106RZ4	Peptidase U32
K04M5_25460	ENOG4105C3S	Mate efflux family protein
K04M5_25490	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
K04M5_25500	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
K04M5_25510	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
K04M5_25520	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
K04M5_25530	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
K04M5_25540	ENOG4105CHV	Transcription elongation factor NusA
K04M5_25550	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
K04M5_25590	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
K04M5_25600	ENOG4105EEI	dihydropteroate synthase
K04M5_25610	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
K04M5_25620	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
K04M5_25630	ENOG4105HBR	Rna-binding protein
K04M5_25640	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
K04M5_25650	ENOG4107QE9	Inherit from COG: Membrane
K04M5_25660	ENOG4106HRJ	d-alanyl-d-alanine carboxypeptidase
K04M5_25680	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
K04M5_25690	ENOG4105DR5	peptidase
K04M5_25720	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
K04M5_25730	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
K04M5_25740	ENOG4105F4G	Membrane
K04M5_25750	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
K04M5_25760	ENOG4105BZU	Histidine kinase
K04M5_25770	ENOG4107QRA	Extracellular solute-binding protein, family 5
K04M5_25790	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
K04M5_25800	ENOG4105C3U	ABC transporter
K04M5_25810	ENOG4108JQ7	(ABC) transporter
K04M5_25830	ENOG4105RD7	BadF BadG BcrA BcrD
K04M5_25840	ENOG4105E2D	ec 3.2.1.52
K04M5_25870	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
K04M5_25910	ENOG4108YZA	Nitrogen regulatory protein pii
K04M5_25920	ENOG4105XTV	UPF0231 protein
K04M5_25930	ENOG4107QIJ	Aconitate hydratase 2
K04M5_25940	ENOG4105D78	K07001 NTE family protein
K04M5_25950	ENOG4105BZ4	penicillin-binding protein
K04M5_25960	ENOG4105CQ7	ATP-dependent helicase
K04M5_25970	ENOG4105PW4	Sugar fermentation stimulation protein homolog
K04M5_25980	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
K04M5_25990	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
K04M5_26000	ENOG4105DJ0	Poly(A) Polymerase
K04M5_26010	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
K04M5_26020	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
K04M5_26030	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
K04M5_26040	ENOG4105D1S	lipid A biosynthesis
K04M5_26050	ENOG4105E3A	(ABC) transporter
K04M5_26060	ENOG4105DA5	(ABC) transporter
K04M5_26070	ENOG4105CHH	sulfate transporter
K04M5_26080	ENOG41077A9	carbonic anhydrase
K04M5_26090	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
K04M5_26100	ENOG410630P	Transcriptional regulator
K04M5_26110	ENOG4107QN2	dihydrolipoyl dehydrogenase
K04M5_26120	ENOG4107QSN	dihydrolipoamide acetyltransferase
K04M5_26130	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
K04M5_26140	ENOG41073TP	transcriptional regulator
K04M5_26160	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
K04M5_26170	ENOG4105KHS	type IV fimbrial pilin protein
K04M5_26180	ENOG4107QHF	type ii secretion system protein e
K04M5_26190	ENOG4105D7Q	type ii secretion system
K04M5_26200	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
K04M5_26210	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
K04M5_26220	ENOG4105DHA	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity (By similarity)
K04M5_26230	ENOG41067SF	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity)
K04M5_26240	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
K04M5_26250	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
K04M5_26260	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
K04M5_26270	ENOG4105K5M	30s ribosomal protein S16
K04M5_26280	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
K04M5_26290	ENOG4106KVJ	cytochrome C assembly protein
K04M5_26300	ENOG4108JU6	CBS domain protein
K04M5_26330	ENOG4105D9M	gamma-glutamylcysteine synthetase
K04M5_26350	ENOG4105W39	Membrane
K04M5_26370	ENOG4105D9Q	decarboxylase (Beta subunit)
K04M5_26380	ENOG4107QSA	Oxaloacetate decarboxylase
K04M5_26500	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
K04M5_26510	ENOG4105CFH	Aspartokinase
K04M5_26520	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
K04M5_26530	ENOG4105Y3E	Modulates RecA activity (By similarity)
K04M5_26540	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
K04M5_26550	ENOG4107TH8	cina domain protein
K04M5_26560	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
K04M5_26570	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
K04M5_26590	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
K04M5_26600	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
K04M5_26610	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
K04M5_26620	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
K04M5_26630	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
K04M5_26640	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
K04M5_26650	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
K04M5_26660	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
K04M5_26670	ENOG4105DXN	mazG family
K04M5_26690	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
K04M5_26700	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
K04M5_26710	ENOG4105BZU	Histidine kinase
K04M5_26720	ENOG4105KJV	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
K04M5_26730	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
K04M5_26740	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
K04M5_26750	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
K04M5_26760	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
K04M5_26770	ENOG4105C3F	Signal peptidase i
K04M5_26780	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
K04M5_26820	ENOG4105EMN	RNA polymerase sigma factor
K04M5_26830	ENOG4108IYU	L-aspartate oxidase
K04M5_26850	ENOG4105Y75	tpr repeat protein
K04M5_26860	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
K04M5_26890	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
K04M5_26900	ENOG4105D0A	hydroxylase
K04M5_26920	ENOG4107YUN	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
K04M5_26930	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
K04M5_26940	ENOG4105E66	phosphoriboisomerase A
K04M5_26950	ENOG4108JQ1	Dehydrogenase
K04M5_26960	ENOG4105MPN	Membrane
K04M5_26970	ENOG4105CXD	Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity)
K04M5_27000	ENOG4105D64	Mechanosensitive ion channel
K04M5_27010	ENOG4105D2N	Aldolase
K04M5_27020	ENOG4105BZA	Phosphoglycerate kinase
K04M5_27030	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
K04M5_27040	ENOG4105D05	Receptor
K04M5_27050	ENOG4108R4R	Iron-regulated virulence regulatory protein
K04M5_27060	ENOG4105CV1	Transketolase (EC 2.2.1.1)
K04M5_27070	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
K04M5_27090	ENOG4105GPY	SprT protein
K04M5_27100	ENOG4105RWS	endonuclease I
K04M5_27110	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
K04M5_27120	ENOG4105D7Z	glutathione synthase
K04M5_27130	ENOG4108UJU	UPF0301 protein
K04M5_27140	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
K04M5_27150	ENOG4105CZX	twitching motility protein
K04M5_27160	ENOG4105CZX	twitching motility protein
K04M5_27170	ENOG4105DFA	alanine racemase domain protein
K04M5_27180	ENOG4105II7	pyrroline-5-carboxylate reductase
K04M5_27190	ENOG4108VIA	integral membrane protein
K04M5_27200	ENOG4105VZ9	UPF0235 protein
K04M5_27220	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
K04M5_27230	ENOG4105CSA	Coproporphyrinogen iii oxidase
K04M5_27240	ENOG4105CSV	Glutaminase
K04M5_27260	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
K04M5_27270	ENOG4105CEN	a g-specific adenine glycosylase
K04M5_27280	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
K04M5_27370	ENOG4105C8Q	Methyl-accepting chemotaxis
K04M5_27430	ENOG4105C26	Dehydrogenase
K04M5_27520	ENOG4108ESY	Metal dependent phosphohydrolase
K04M5_27530	ENOG4105ETE	Transcriptional regulator (LacI family
K04M5_27540	ENOG410901P	UPF0249 protein
K04M5_27550	ENOG4105F8D	glycoside hydrolase family 4
K04M5_27560	ENOG4105VCP	PTS System
K04M5_27570	ENOG4105CK1	PTS System
K04M5_27610	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
K04M5_27620	ENOG4105EXU	Membrane
K04M5_27640	ENOG4108K5H	permease YjgP YjgQ family protein
K04M5_27650	ENOG4108M8S	permease YjgP YjgQ family protein
K04M5_27660	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
K04M5_27670	ENOG4105MYG	DNA polymerase iii, chi subunit
K04M5_27680	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
K04M5_27700	ENOG4108MJ3	acetyltransferase
K04M5_27730	ENOG4105CEU	Arginine dihydrolase
K04M5_27740	ENOG4105DBV	ornithine carbamoyltransferase
K04M5_27760	ENOG4105CXT	aspartate transcarbamylase
K04M5_27770	ENOG4108R9M	Involved in allosteric regulation of aspartate carbamoyltransferase (By similarity)
K04M5_27780	ENOG4105KME	endoribonuclease L-psp
K04M5_27790	ENOG4107S7E	1-acyl-sn-glycerol-3-phosphate acyltransferase
K04M5_27800	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
K04M5_27810	ENOG4105VFK	BolA family
K04M5_27830	ENOG4105E3I	toluene tolerance
K04M5_27840	ENOG4107PE3	Mammalian cell entry related domain protein
K04M5_27850	ENOG4105CY3	ABC transporter, permease
K04M5_27860	ENOG4105DHJ	ABC, transporter
K04M5_27880	ENOG4105C2X	Arabinose 5-phosphate isomerase
K04M5_27900	ENOG4105WI0	lipopolysaccharide transport periplasmic protein lptA
K04M5_27910	ENOG4108IUZ	ABC transporter
K04M5_27920	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
K04M5_27930	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
K04M5_27940	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
K04M5_27950	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
K04M5_27960	ENOG41080Z8	PHOSPHOCARRIER protein
K04M5_27970	ENOG4105CJW	magnesium transporter
K04M5_27980	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
K04M5_27990	ENOG4105N42	UPF0307 protein
K04M5_28000	ENOG4105C5I	Dehydrogenase
K04M5_28010	ENOG4105D3G	Pseudouridine synthase
K04M5_28020	ENOG4105K3M	)-transporter
K04M5_28030	ENOG4105BZK	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity)
K04M5_28040	ENOG4108IAB	Phoh family
K04M5_28050	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
K04M5_28070	ENOG4105QD6	exported protein
K04M5_28080	ENOG4105C03	ribonuclease
K04M5_28090	ENOG4108Z03	MAF-like protein
K04M5_28100	ENOG4105VQ7	Rod shape-determining protein MreD
K04M5_28110	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
K04M5_28120	ENOG4105DFF	Rod shape-determining protein mreb
K04M5_28190	ENOG4108VAU	general secretion pathway protein G
K04M5_28210	ENOG4105D7Q	type ii secretion system
K04M5_28220	ENOG4107QHF	type ii secretion system protein e
K04M5_28290	ENOG41062P1	Diguanylate cyclase phosphodiesterase
K04M5_28300	ENOG4108UUM	single-stranded DNA-binding protein
K04M5_28310	ENOG41086KC	Transcriptional regulator
K04M5_28320	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
K04M5_28330	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
K04M5_28370	ENOG4105C5R	Aminotransferase
K04M5_28380	ENOG4105CFH	Aspartokinase
K04M5_28390	ENOG4105C3R	Methionine synthase
K04M5_28400	ENOG4105EEQ	Na H antiporter
K04M5_28520	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
K04M5_28530	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
K04M5_28540	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
K04M5_28580	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
K04M5_28590	ENOG4105MYN	Zinc uptake regulation protein
K04M5_28610	ENOG4107QP8	phosphohexose isomerase
K04M5_28620	ENOG4108YXI	Secondary thiamine-phosphate synthase enzyme
K04M5_28630	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
K04M5_28640	ENOG4105CDU	Replicative dna helicase
K04M5_28660	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
K04M5_28670	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
K04M5_28680	ENOG4108VDV	Binds single-stranded DNA at the primosome assembly site (PAS) (By similarity)
K04M5_28690	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
K04M5_28700	ENOG4105DJV	ribulose-phosphate 3-epimerase
K04M5_28710	ENOG4105DFE	Dna adenine methylase
K04M5_28730	ENOG4105D49	3-dehydroquinate synthase
K04M5_28740	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
K04M5_28750	ENOG4105E4G	Type IV pilus
K04M5_28800	ENOG4108JQC	penicillin-binding protein 1A
K04M5_28810	ENOG4105C5Q	Transcriptional regulator
K04M5_28820	ENOG4105EHV	domain protein
K04M5_28830	ENOG4107QN2	dihydrolipoyl dehydrogenase
K04M5_28860	ENOG4105CH7	arginosuccinase
K04M5_28870	ENOG4105CDH	Citrulline--aspartate ligase
K04M5_28880	ENOG4105CAS	nag kinase
K04M5_28890	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
K04M5_28900	ENOG4105CWC	Acetylornithine deacetylase
K04M5_28910	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
K04M5_28930	ENOG4105SYT	Methylenetetrahydrofolate reductase
K04M5_28940	ENOG4105CFH	Aspartokinase
K04M5_28950	ENOG4105C28	cystathionine
K04M5_28960	ENOG4105GGQ	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis (By similarity)
K04M5_28970	ENOG4105C6K	Malic enzyme
K04M5_28980	ENOG4108UQY	Iron-storage protein
K04M5_28990	ENOG4105W53	bacterioferritin-associated ferredoxin
K04M5_29000	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
K04M5_29010	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
K04M5_29020	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
K04M5_29030	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
K04M5_29050	ENOG4108ZKU	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (By similarity)
K04M5_29060	ENOG4108ZAT	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE (By similarity)
K04M5_29070	ENOG4105WWK	YheO domain protein
K04M5_29080	ENOG4108V1T	peptidylprolyl cis-trans isomerase
K04M5_29100	ENOG41069P5	Protein slyX homolog
K04M5_29110	ENOG4105D44	asparaginase
K04M5_29120	ENOG4108YZY	peptidylprolyl cis-trans isomerase
K04M5_29150	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
K04M5_29160	ENOG4105C5H	ABC transporter
K04M5_29180	ENOG4105DNZ	Alpha Beta Hydrolase
K04M5_29190	ENOG4105YP7	UPF0270 protein
K04M5_29200	ENOG4105CJE	phosphoribulokinase (EC 2.7.1.19)
K04M5_29210	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
K04M5_29230	ENOG4105C26	Dehydrogenase
K04M5_29250	ENOG4105C8Y	Acetylornithine aminotransferase
K04M5_29260	ENOG4105DDQ	anthranilate synthase
K04M5_29290	ENOG4105C31	Tryptophanyl-tRNA synthetase
K04M5_29300	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
K04M5_29310	ENOG4105C2N	RNA methyltransferase TrmH family group 3
K04M5_29320	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
K04M5_29330	ENOG4105KPV	Transcriptional regulator
K04M5_29340	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
K04M5_29350	ENOG4108UV7	flagellar protein motX
K04M5_29360	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
K04M5_29380	ENOG4105EPW	hflc protein
K04M5_29390	ENOG4107QJR	hflk protein
K04M5_29400	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
K04M5_29410	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
K04M5_29420	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
K04M5_29430	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
K04M5_29440	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
K04M5_29450	ENOG4105K8N	protein family UPF0079, ATPase
K04M5_29470	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
K04M5_29600	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
K04M5_29610	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
K04M5_29620	ENOG4105DJ4	phosphatidylserine decarboxylase
K04M5_29630	ENOG4105C8P	)-transporter
K04M5_29650	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
K04M5_29660	ENOG4107YZP	Rhodanese domain protein
K04M5_29670	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
K04M5_29680	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
K04M5_29690	ENOG4105D7W	serine acetyltransferase
K04M5_29700	ENOG41063SB	peptidase
K04M5_29720	ENOG41062JF	Transcriptional regulator
K04M5_29740	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
K04M5_29760	ENOG4105E33	succinate dehydrogenase
K04M5_29770	ENOG4108WJH	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity)
K04M5_29780	ENOG4108VP9	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity)
K04M5_29800	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
K04M5_29810	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
K04M5_29820	ENOG4105KT7	mgtC SapB transporter
K04M5_29840	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
K04M5_29850	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
K04M5_29860	ENOG4107QI1	Mate efflux family protein
K04M5_29870	ENOG4105CTQ	phosphohexokinase
K04M5_29880	ENOG41076HS	cation diffusion facilitator family transporter
K04M5_29890	ENOG4108SPG	Periplasmic Protein
K04M5_29900	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
K04M5_29910	ENOG4105E0F	Histidine kinase
K04M5_29930	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
K04M5_29940	ENOG4108YH1	overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7
K04M5_29950	ENOG4108IJ0	Aspartate ammonia-lyase
K04M5_29960	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
K04M5_29970	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
K04M5_29990	ENOG4105C3N	Participates in control of cell volume in low-osmolarity conditions (By similarity)
K04M5_30010	ENOG4107QN1	sodium solute
K04M5_30040	ENOG4105C9Q	fumarate hydratase class II
K04M5_30050	ENOG4105BZU	Histidine kinase
K04M5_30060	ENOG4105D8G	Major Facilitator superfamily
K04M5_30090	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
K04M5_30100	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
K04M5_30110	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
K04M5_30120	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
K04M5_30130	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
K04M5_30140	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
K04M5_30150	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
K04M5_30170	ENOG4105C5H	ABC transporter
K04M5_30270	ENOG4105CXN	decarboxylase
K04M5_30280	ENOG4105D5Q	Arginine ornithine antiporter
K04M5_30290	ENOG4108M3R	transcriptional activator CadC
K04M5_30300	ENOG4105W1Y	Transcriptional regulator
K04M5_30310	ENOG4105DC1	bifunctional purine biosynthesis protein purh
K04M5_30320	ENOG4105C12	Phosphoribosylglycinamide synthetase
K04M5_30360	ENOG4105R2J	Conserved Protein
K04M5_30370	ENOG4105JPG	D-isomer specific 2-hydroxyacid dehydrogenase
K04M5_30380	ENOG4108RG0	uracil-dna glycosylase
K04M5_30390	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
K04M5_30400	ENOG4105E09	nadh pyrophosphatase
K04M5_30410	ENOG4108ZVW	Anti-RNA polymerase sigma 70 factor
K04M5_30420	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
K04M5_30430	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
K04M5_30440	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
K04M5_30450	ENOG4108VZM	50s ribosomal protein L10
K04M5_30460	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
K04M5_30470	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
K04M5_30480	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
K04M5_30490	ENOG4105PM1	preprotein translocase subunit SecE
K04M5_30500	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
K04M5_30550	ENOG4105CS9	pantothenic acid kinase
K04M5_30560	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
K04M5_30570	ENOG4105D4A	Cell wall formation (By similarity)
K04M5_30590	ENOG4105JIM	Phosphatidylserine synthase
K04M5_30740	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
K04M5_30760	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
K04M5_30770	ENOG4107R9T	Catalyzes the formation of 5-methyl-uridine at position 54 (m5U54) in all tRNAs (By similarity)
K04M5_30800	ENOG4105DX1	Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation (By similarity)
K04M5_30810	ENOG4107R73	Mate efflux family protein
K04M5_30830	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
K04M5_30840	ENOG4105E55	glycerol-3-phosphate acyltransferase
K04M5_30850	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
K04M5_30860	ENOG4105VEI	Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway (By similarity)
K04M5_30870	ENOG4105X6C	Flagellar basal body-associated protein FliL
K04M5_30880	ENOG4105EBW	Rhomboid-type serine protease that catalyzes intramembrane proteolysis (By similarity)
K04M5_30890	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
K04M5_30900	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
K04M5_30910	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
K04M5_30920	ENOG4105CAK	Cell division ATP-binding protein ftsE
K04M5_30930	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
K04M5_30940	ENOG4106H78	methyltransferase
K04M5_30960	ENOG41076UM	multiple antibiotic resistance (MarC)-related protein
K04M5_31040	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
K04M5_31050	ENOG41082YX	Transcriptional regulator, arsr family
K04M5_31060	ENOG4105D58	Diguanylate phosphodiesterase
K04M5_31070	ENOG410829K	Lysine exporter protein (Lyse ygga)
K04M5_31080	ENOG4108EUD	Lysophospholipase
K04M5_31090	ENOG4105DQF	Hydrolase
K04M5_31120	ENOG4106IUH	DTW domain containing protein
K04M5_31130	ENOG4105BZU	Histidine kinase
K04M5_31140	ENOG4105DFC	had-superfamily hydrolase, subfamily ia, variant
K04M5_31150	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
K04M5_31170	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
K04M5_31180	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
K04M5_31190	ENOG4105XQ6	frataxin-like protein
K04M5_31200	ENOG4107T0K	Adenylate cyclase
K04M5_31210	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
K04M5_31220	ENOG41076E6	Uroporphyrinogen-III Synthase
K04M5_31230	ENOG4105ECF	c-methyltransferase
K04M5_31240	ENOG410601J	HemY protein
K04M5_31320	ENOG4107QK7	reductase
K04M5_31330	ENOG4108ZIT	Ferredoxin, 2FE-2S
K04M5_31340	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
K04M5_31360	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
K04M5_31370	ENOG4105K63	Thioredoxin
K04M5_31380	ENOG4105C1J	atp-dependent rna helicase
K04M5_31390	ENOG4105C9X	ppx gppa phosphatase
K04M5_31410	ENOG4105EX9	Membrane
K04M5_31430	ENOG4105C9U	ATP-dependent DNA helicase RecQ
K04M5_31440	ENOG4105FR1	rard protein
K04M5_31470	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
K04M5_31480	ENOG4105C4R	Atp-dependent dna helicase
K04M5_31500	ENOG4105E18	UPF0276 protein
K04M5_31560	ENOG4105DC7	peptidase M24
K04M5_31560	ENOG4105DC7	peptidase M24
K04M5_31570	ENOG4105D41	biosynthesis protein thiH
K04M5_31580	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
K04M5_31590	ENOG4105WHD	thiamine biosynthesis protein ThiS
K04M5_31600	ENOG4105D06	uba thif-type nad fad binding protein
K04M5_31620	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
K04M5_31630	ENOG4105WMR	Protein CrcB homolog
K04M5_31640	ENOG4105E3B	Multicopper oxidase
K04M5_31740	ENOG4108Z0R	Transferase
K04M5_31750	ENOG4105SG3	Protein of unknown function (DUF1488)
K04M5_31760	ENOG4105E2X	shikimate dehydrogenase
K04M5_31770	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
K04M5_31780	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
K04M5_31790	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
K04M5_31800	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
K04M5_31810	ENOG4108WI1	Dna topoisomerase
K04M5_31820	ENOG4108RPN	Protein smg homolog
K04M5_31830	ENOG4105C79	DNA protecting protein DprA
K04M5_31850	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
K04M5_31860	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
K04M5_31870	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
K04M5_31880	ENOG4105C1A	potassium transporter peripheral membrane
K04M5_31890	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
K04M5_31910	ENOG4108UT2	hemolysin iii
K04M5_31920	ENOG4108N23	SpoOM-related protein
K04M5_31940	ENOG4105PC1	Conserved Protein
K04M5_31960	ENOG4105E27	serine threonine protein kinase
K04M5_31970	ENOG4108Z33	Thiol disulfide Interchange Protein
K04M5_31980	ENOG4106HNH	Acyl-transferase
K04M5_32000	ENOG4105C0P	Mg chelatase subunit ChlI
K04M5_32020	ENOG4105P3Y	Acetolactate synthase 2 regulatory subunit
K04M5_32030	ENOG4105CM2	brancheD-chain amino acid aminotransferase
K04M5_32040	ENOG4105C01	Dihydroxy-acid dehydratase
K04M5_32050	ENOG4105C7B	Threonine dehydratase
K04M5_32060	ENOG4105F52	Transcriptional regulator
K04M5_32070	ENOG4105CZQ	inner membrane transport protein YdhC
K04M5_32080	ENOG4105F87	Dehydratase
K04M5_32090	ENOG4105EAD	ABC transporter
K04M5_32100	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
K04M5_32120	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
K04M5_32130	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
K04M5_32140	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
K04M5_32150	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
K04M5_32160	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
K04M5_32180	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
K04M5_32190	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
K04M5_32200	ENOG410684E	atp synthase
K04M5_32210	ENOG4105FA0	parb-like partition protein
K04M5_32220	ENOG4107QJE	Chromosome Partitioning Protein
K04M5_32230	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
K04M5_32240	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
K04M5_32250	ENOG4105QTB	Flavodoxin
K04M5_32260	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
K04M5_32270	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
K04M5_32280	ENOG4105NVJ	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
K04M5_32300	ENOG4105CDA	abc transporter atp-binding protein
K04M5_32310	ENOG4105E5Q	amino acid AbC transporter
K04M5_32320	ENOG4105EAB	amino acid AbC transporter
K04M5_32350	ENOG4105E0I	Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) (By similarity)
K04M5_32380	ENOG4105EQ2	LysR family Transcriptional regulator
K04M5_32390	ENOG4105EC3	peptidase S51, dipeptidase E
K04M5_32400	ENOG4105FCK	Membrane
K04M5_32410	ENOG4105C5Y	PTS System
K04M5_32420	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
K04M5_32430	ENOG4108PSC	Represses the expression of the murPQ operon involved in the uptake and degradation of N-acetylmuramic acid (MurNAc). Binds to two adjacent inverted repeats within the operator region. MurNAc 6-phosphate, the substrate of MurQ, is the specific inducer that weakens binding of MurR to the operator (By similarity)
K04M5_32450	ENOG4108J59	Extracellular solute-binding protein, family 5
K04M5_32490	ENOG4108JJA	ABC, transporter
K04M5_32520	ENOG4107QZV	Type I secretion membrane fusion protein
K04M5_32530	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
K04M5_32540	ENOG4105CQZ	Histidine kinase
K04M5_32550	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
K04M5_32580	ENOG4105C26	Dehydrogenase
K04M5_32600	ENOG4105CK7	Sodium proline symporter
K04M5_32660	ENOG4105EW9	transcriptional regulator AsnC family
K04M5_32680	ENOG4105BZ1	(ABC) transporter
K04M5_32700	ENOG4105C1J	atp-dependent rna helicase
K04M5_32710	ENOG4108RPX	mosc domain containing protein
K04M5_32760	ENOG4105ECQ	AraC Family Transcriptional Regulator
K04M5_32800	ENOG4108JU3	Alkyl hydroperoxide reductase
K04M5_32810	ENOG4105D3R	alkyl hydroperoxide reductase
K04M5_32890	ENOG4105K56	Transcriptional regulator
K04M5_32900	ENOG4108ZHJ	Organic hydroperoxide resistance protein
K04M5_32980	ENOG4105C19	ABC transporter
K04M5_33020	ENOG4105CI1	PTS System
K04M5_33030	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
K04M5_33040	ENOG4105DHQ	Histidine kinase
K04M5_33050	ENOG4108JP0	extracellular solute-binding protein family 1
K04M5_33060	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
K04M5_33070	ENOG4105DBM	Siderophore biosynthesis protein
K04M5_33090	ENOG4105DUU	IucA IucC family protein
K04M5_33110	ENOG4105E0K	tonB-dependent siderophore receptor
K04M5_33120	ENOG4105GAV	receptor
K04M5_33130	ENOG4108HUF	Transporter
K04M5_33140	ENOG4105DQ5	transport system permease protein
K04M5_33150	ENOG4108U1V	ABC transporter, permease
K04M5_33160	ENOG4105E0A	ABC, transporter
K04M5_33170	ENOG4105C8Q	Methyl-accepting chemotaxis
K04M5_33180	ENOG4107RAN	Peptidase, M16
K04M5_33200	ENOG4105DR5	peptidase
K04M5_33230	ENOG4105E5M	Multidrug resistance protein D
K04M5_33250	ENOG4105ETE	Transcriptional regulator (LacI family
K04M5_33260	ENOG4107RJ1	sodium solute
K04M5_33290	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
K04M5_33310	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
K04M5_33320	ENOG4105ETE	Transcriptional regulator (LacI family
K04M5_33330	ENOG4105CNV	Aldolase
K04M5_33340	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
K04M5_33350	ENOG4105CHR	reductase
K04M5_33370	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
K04M5_33400	ENOG4105D2S	major facilitator superfamily
K04M5_33420	ENOG4105EJQ	L-serine dehydratase
K04M5_33440	ENOG4108KDD	Involved in the transport of maltose and maltodextrins (By similarity)
K04M5_33480	ENOG4108K8S	endonuclease I
K04M5_33520	ENOG4105CXN	decarboxylase
K04M5_33530	ENOG4105D5Q	Arginine ornithine antiporter
K04M5_33550	ENOG4107XGF	functions in a salvage pathway. Uses pyridoxamine (By similarity)
K04M5_33560	ENOG4107QV7	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) (By similarity)
K04M5_33570	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
K04M5_33620	ENOG41061ZR	Transcriptional regulator
K04M5_33630	ENOG4107QQN	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
K04M5_33640	ENOG4107RTM	4-alpha-glucanotransferase (EC 2.4.1.25)
K04M5_33650	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
K04M5_33660	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
K04M5_33670	ENOG4107T9C	Alpha amylase catalytic region
K04M5_33690	ENOG41074DU	domain protein
K04M5_33700	ENOG4108P2H	Inner membrane protein YjiG
K04M5_33710	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
K04M5_33730	ENOG4105CK2	sodium dicarboxylate symporter
K04M5_33750	ENOG4105F04	LysR family Transcriptional regulator
K04M5_33760	ENOG4105N0V	mono-oxygenase ydhR
K04M5_33790	ENOG4105KJF	protein tyrosine phosphatase
K04M5_33800	ENOG4105DAY	polysaccharide export protein
K04M5_33830	ENOG41081FY	multiple antibiotic resistance (MarC)-related
K04M5_33840	ENOG4108NRW	Phospholipase, patatin family
K04M5_33850	ENOG4108M1A	Chitin-binding protein
K04M5_33870	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
K04M5_33890	ENOG4105C72	UPF0176 protein
K04M5_33910	ENOG4105DZ1	carboxypeptidase
K04M5_33930	ENOG4108ZX5	transcriptional regulator
K04M5_33940	ENOG4108RCM	Nitroreductase
K04M5_33960	ENOG4105ETT	transcriptional Regulator, LysR family
K04M5_33970	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
K04M5_34000	ENOG4105DP0	ferredoxin-NADP reductase
K04M5_34020	ENOG41068P6	UPF0319 protein
K04M5_34030	ENOG4105IPI	Membrane
K04M5_34080	ENOG4105DSW	Fusaric acid resistance protein
K04M5_34100	ENOG4105G2Y	Transcriptional regulator
K04M5_34110	ENOG4105CNH	Multidrug resistance protein MdtL
K04M5_34130	ENOG4105I4A	GCN5-related N-acetyltransferase
K04M5_34150	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
K04M5_34160	ENOG4105EB3	Histidine kinase
K04M5_34190	ENOG4107T9Z	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
K04M5_34200	ENOG4105F1A	Pyruvate formate-lyase
K04M5_34210	ENOG4105C6N	Formate acetyltransferase
K04M5_34250	ENOG4105KWG	Pfam:DUF1696
K04M5_34280	ENOG4105ER2	Ompa motb domain protein
K04M5_34290	ENOG4107RD7	Flagellar Motor Protein, MotA
K04M5_34340	ENOG4105MQ3	flagellar protein FliS
K04M5_34350	ENOG410804A	Flagellar hook-associated 2 domain-containing protein
K04M5_34370	ENOG4105I03	Flagellin
K04M5_34400	ENOG4105D00	flagellar biosynthetic protein flhB
K04M5_34410	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
K04M5_34420	ENOG4105VS8	Flagellar biosynthetic protein fliq
K04M5_34430	ENOG4105CN7	Flagellar biosynthetic protein FliP
K04M5_34440	ENOG4105DD5	Flagellar motor switch protein
K04M5_34470	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
K04M5_34490	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
K04M5_34500	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
K04M5_34520	ENOG4108JIR	Flagellum-specific ATP synthase
K04M5_34580	ENOG4107SSZ	Phosphatase
K04M5_34610	ENOG4108YZK	glyoxalase bleomycin resistance protein dioxygenase
K04M5_34620	ENOG4105EXG	Transcriptional regulator
K04M5_34660	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
K04M5_34680	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
K04M5_34710	ENOG4105BZU	Histidine kinase
K04M5_34720	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
K04M5_34730	ENOG4105CPQ	Dehydrogenase
K04M5_34800	ENOG4105D64	Mechanosensitive ion channel
K04M5_34820	ENOG4105DMF	Dehydrogenase
K04M5_34830	ENOG4105DAA	L-lactate
K04M5_34840	ENOG410642W	LysR family Transcriptional regulator
K04M5_34860	ENOG4108JQ5	ABC transporter
K04M5_34880	ENOG4105DAN	ATP-dependent protease
K04M5_34900	ENOG4107QE9	Inherit from COG: Membrane
K04M5_34910	ENOG4105YE1	PilZ domain
K04M5_34940	ENOG4105WCN	acetyltransferase
K04M5_34950	ENOG4108BGM	Quinol dehydrogenase periplasmic component
K04M5_34960	ENOG4105GXZ	Ferredoxin-type protein NapH
K04M5_35000	ENOG4108JJB	ABC transporter
K04M5_35010	ENOG4108V7D	UPF0397 protein
K04M5_35020	ENOG4105EFX	secretion protein, HlyD family
K04M5_35030	ENOG4105KK7	inner membrane protein YiaW
K04M5_35040	ENOG4106TD9	Diguanylate cyclase
K04M5_35070	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
K04M5_35080	ENOG4107SEY	Conserved Protein
K04M5_35090	ENOG4108XDN	Transcriptional regulator
K04M5_35100	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
K04M5_35110	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
K04M5_35130	ENOG4105C1J	atp-dependent rna helicase
K04M5_35140	ENOG4105CUG	Oligopeptidase b
K04M5_35150	ENOG4107ENK	receptor
K04M5_35190	ENOG4108NVR	Methyl-accepting chemotaxis
K04M5_35200	ENOG4107S17	Phosphate-binding protein
K04M5_35210	ENOG4105C8U	phosphate abc transporter
K04M5_35220	ENOG4105E2Z	phosphate ABC transporter (Permease
K04M5_35230	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
K04M5_35260	ENOG4107QVM	von Willebrand factor, type A
K04M5_35300	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
K04M5_35310	ENOG4105C8Q	Methyl-accepting chemotaxis
K04M5_35330	ENOG41086KC	Transcriptional regulator
K04M5_35340	ENOG41086KC	Transcriptional regulator
K04M5_35360	ENOG4108JJ6	Type I secretion system ATPase
K04M5_35390	ENOG4105S6R	Iron-hydroxamate transporter permease subunit
K04M5_35400	ENOG4108HUF	Transporter
K04M5_35410	ENOG4105E0A	ABC, transporter
K04M5_35420	ENOG4105E0K	tonB-dependent siderophore receptor
K04M5_35430	ENOG4105BZ1	(ABC) transporter
K04M5_35490	ENOG4105ETT	transcriptional Regulator, LysR family
K04M5_35630	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
K04M5_35640	ENOG41069D7	Methyl-accepting chemotaxis
K04M5_35680	ENOG41086KC	Transcriptional regulator
K04M5_35760	ENOG4105S6R	Iron-hydroxamate transporter permease subunit
K04M5_35770	ENOG4108HUF	Transporter
K04M5_35780	ENOG4105E0A	ABC, transporter
K04M5_35790	ENOG4105E0K	tonB-dependent siderophore receptor
K04M5_35800	ENOG4105BZ1	(ABC) transporter
K04M5_35840	ENOG4105CZN	Potassium uptake protein
K04M5_35850	ENOG4105ETT	transcriptional Regulator, LysR family
K04M5_35870	ENOG4105DVW	rieske (2Fe-2S)
K04M5_35880	ENOG4105C26	Dehydrogenase
K04M5_35890	ENOG4107QZF	nitrite reductase NADPH large subunit
K04M5_35900	ENOG4105CJP	fad dependent oxidoreductase
K04M5_35930	ENOG4107UW8	HAD-superfamily hydrolase subfamily IA variant 3
K04M5_35990	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
K04M5_36000	ENOG4105CH6	catalase
K04M5_36010	ENOG4108RXX	maleylacetoacetate isomerase
K04M5_36020	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
K04M5_36030	ENOG4108WUH	Transcriptional regulator, TetR family
K04M5_36040	ENOG4105V0I	UPF0267 protein
K04M5_36120	ENOG4108F2G	Chain length determinant protein
K04M5_36150	ENOG4105D3Q	Sugar transferase
K04M5_36160	ENOG4108IJ9	(ABC) transporter
K04M5_36170	ENOG4107FKK	extracellular solute-binding protein family 1
K04M5_36180	ENOG4105D56	permease protein
K04M5_36190	ENOG4105EG2	ABC transporter, permease
K04M5_36250	ENOG4105CKW	Inner membrane protein yedI
K04M5_36260	ENOG4105EKE	dihydroorotase
K04M5_36280	ENOG4105QVC	MOSC domain-containing protein
K04M5_36280	ENOG4105QVC	MOSC domain-containing protein
K04M5_36290	ENOG4107RA1	nh(3)-dependent nad( ) synthetase
K04M5_36300	ENOG4107X4V	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
K04M5_36380	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
K04M5_36390	ENOG4105EHG	Permease protein
K04M5_36410	ENOG4106GFD	transport protein
K04M5_36420	ENOG41090AP	transport protein
K04M5_36430	ENOG4105WQ5	TonB family
K04M5_36440	ENOG4105D4P	Coproporphyrinogen iii oxidase
K04M5_36450	ENOG41090JE	Utilization Protein
K04M5_36460	ENOG4105PYN	Pyridoxamine 5-phosphate oxidase-related
K04M5_36480	ENOG4107R88	Chemotaxis protein (CheV)
K04M5_36490	ENOG4105KQ5	peptidylprolyl cis-trans isomerase
K04M5_36500	ENOG4107R73	Mate efflux family protein
K04M5_36510	ENOG4105C3U	ABC transporter
K04M5_36520	ENOG4108JQ7	(ABC) transporter
K04M5_36530	ENOG4105DEF	Extracellular solute-binding protein, family 5
K04M5_36550	ENOG4105MVE	transcriptional regulator
K04M5_36560	ENOG4105ZXK	Dehydrogenase
K04M5_36570	ENOG4105G63	Type III effector Hrp-dependent
K04M5_36580	ENOG4105FB2	class II Aldolase
K04M5_36590	ENOG4105QG4	Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity)
K04M5_36600	ENOG4105EXW	epimerase dehydratase
K04M5_36610	ENOG4105C6Z	Gluconate
K04M5_36620	ENOG41090EM	Repressor of rcnA expression. Acts by binding specifically to the rcnA promoter in the absence of nickel and cobalt. In the presence of one of these metals, it has a weaker affinity for rcnA promoter
K04M5_36630	ENOG41061MD	high-affinity nickel-transporter
K04M5_36640	ENOG4105C8Q	Methyl-accepting chemotaxis
K04M5_36650	ENOG4105CR8	Transcriptional regulator
K04M5_36680	ENOG4105KXC	Collagenase
K04M5_36700	ENOG4108UWZ	4-Carboxymuconolactone decarboxylase
K04M5_36710	ENOG4105VUF	Transcriptional regulator
K04M5_36750	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
K04M5_36760	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
K04M5_36770	ENOG4108M6U	Universal stress protein A
K04M5_36780	ENOG4105C5H	ABC transporter
K04M5_36810	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
K04M5_36830	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
K04M5_36850	ENOG4108HK0	-acetyltransferase
K04M5_36900	ENOG4108IJF	Heavy metal efflux pump, CzcA
K04M5_36940	ENOG4108IEG	Formate dehydrogenase Alpha subunit
K04M5_36960	ENOG4107QWP	ABC-2 type transporter
K04M5_36970	ENOG4105CJ1	ABC, transporter
K04M5_37030	ENOG4108IA2	Sodium pantothenate symporter
K04M5_37040	ENOG4107SS6	2-dehydro-3-deoxygluconokinase
K04M5_37050	ENOG4108UHU	Aldolase
K04M5_37060	ENOG4105E2D	ec 3.2.1.52
K04M5_37070	ENOG4105HHQ	6-phosphogluconolactonase (EC 3.1.1.31)
K04M5_37080	ENOG4107YYT	May reduce aminoacrylate peracid to aminoacrylate. Required to remove a toxic intermediate produce by the pyrimidine nitrogen degradation (By similarity)
K04M5_37090	ENOG4105JAB	phenazine biosynthesis protein, phzf family
K04M5_37100	ENOG4108V1U	phospholipid-binding protein
K04M5_37120	ENOG4105D6J	arsenicaL-resistance protein
K04M5_37150	ENOG4105KVH	Transcriptional regulator
K04M5_37200	ENOG4105JQN	Transcriptional regulator
K04M5_37210	ENOG4107RGM	aldo keto reductase
K04M5_37260	ENOG4105E0U	tyrosine-specific transport protein
K04M5_37280	ENOG4105C8Q	Methyl-accepting chemotaxis
K04M5_37290	ENOG4105DWD	nucleoside recognition domain protein
K04M5_37330	ENOG4105DR5	peptidase
K04M5_37350	ENOG4105CR8	Transcriptional regulator
K04M5_37360	ENOG4105E5M	Multidrug resistance protein D
K04M5_37390	ENOG4105VW4	glutaredoxin 3
K04M5_37400	ENOG4108SXK	Transporter Drug Metabolite Exporter family
K04M5_37430	ENOG4105FBJ	fumarylacetoacetate (faa) hydrolase
K04M5_37520	ENOG4105FT1	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I (By similarity)
K04M5_37560	ENOG4107TQK	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group (By similarity)
K04M5_37570	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
K04M5_37580	ENOG4108V1T	peptidylprolyl cis-trans isomerase
K04M5_37600	ENOG4105CDV	Ompa motb domain protein
K04M5_37640	ENOG4105VEQ	Cold shock protein
K04M5_37650	ENOG4105VCN	Rescues the ribosomes stalled at the 3' end of non-stop mRNAs. May induce hydrolysis of the ribosome-bound peptidyl-tRNA. This activity is crucial when the stalled ribosome can not be rescued by the SsrA(tmRNA)-SmpB quality control system
K04M5_37660	ENOG4105BZU	Histidine kinase
K04M5_37670	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
K04M5_37690	ENOG4105BZ1	(ABC) transporter
K04M5_37700	ENOG4105BZ1	(ABC) transporter
K04M5_37710	ENOG4105DFG	type I secretion outer membrane protein
K04M5_37720	ENOG4108MGY	Histidine kinase
K04M5_37770	ENOG4105C8Q	Methyl-accepting chemotaxis
K04M5_37790	ENOG4108RMU	ferritin dps family protein
K04M5_37820	ENOG4105C0A	alcohol dehydrogenase
K04M5_37830	ENOG4108556	Isoprenoid biosynthesis protein with amidotransferase-like domain
K04M5_37880	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
K04M5_37890	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
K04M5_37900	ENOG4105MIR	Phenylalanine 4-monooxygenase
K04M5_37910	ENOG41090A4	Pterin carbinolamine dehydratase
K04M5_37950	ENOG4105VRT	cytoplasmic protein
K04M5_37990	ENOG4105C1J	atp-dependent rna helicase
K04M5_38000	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
K04M5_38020	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
K04M5_38030	ENOG4105VEQ	Cold shock protein
K04M5_38050	ENOG4108KN7	Removes 5-oxoproline from various penultimate amino acid residues except L-proline (By similarity)
K04M5_38070	ENOG4105CKI	cobalamin synthesis protein
K04M5_38080	ENOG4105C1J	atp-dependent rna helicase
K04M5_38120	ENOG4105CXC	rtn protein
K04M5_38130	ENOG4105DKW	ABC transporter
K04M5_38170	ENOG4105CVA	phosphate
K04M5_38200	ENOG4108ENQ	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction (By similarity)
K04M5_38210	ENOG4105C1J	atp-dependent rna helicase
K04M5_38220	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
K04M5_38230	ENOG4105EQ2	LysR family Transcriptional regulator
K04M5_38240	ENOG4105ENX	hydrolase
K04M5_38250	ENOG4105ENX	hydrolase
K04M5_38280	ENOG4105HF0	Membrane
K04M5_38330	ENOG4105CKI	cobalamin synthesis protein
K04M5_38350	ENOG4105DR5	peptidase
K04M5_38370	ENOG4105CKI	cobalamin synthesis protein
K04M5_38390	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
K04M5_38400	ENOG41076UM	multiple antibiotic resistance (MarC)-related protein
K04M5_38420	ENOG4107SDU	Methyl-accepting chemotaxis
K04M5_38440	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
K04M5_38450	ENOG4105E39	Enoyl-CoA hydratase
K04M5_38460	ENOG4107QX3	carboxylase
K04M5_38470	ENOG4105C1G	acyl-Coa dehydrogenase
K04M5_38490	ENOG4105CHU	acetyl-coa acetyltransferase
K04M5_38500	ENOG4105C26	Dehydrogenase
K04M5_38520	ENOG4105E39	Enoyl-CoA hydratase
K04M5_38530	ENOG4105E39	Enoyl-CoA hydratase
K04M5_38540	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
K04M5_38550	ENOG4105CHR	reductase
K04M5_38560	ENOG4105E2S	oxidase) subunit II
K04M5_38570	ENOG4105BZ9	Cytochrome C oxidase, subunit I
K04M5_38580	ENOG4105CCU	oxidase (Subunit III)
K04M5_38600	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
K04M5_38610	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
K04M5_38640	ENOG4105C26	Dehydrogenase
K04M5_38720	ENOG4105E5Z	arginine transporter ATP-binding subunit
K04M5_38730	ENOG4106PMH	Extracellular solute-binding protein family 3
K04M5_38740	ENOG4105GBT	ABC transporter
K04M5_38750	ENOG4105DMR	ABC, transporter
K04M5_38770	ENOG4105DUM	transcriptional regulator, lysR family
K04M5_38800	ENOG4105EXG	Transcriptional regulator
K04M5_38810	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
K04M5_38820	ENOG4105C10	Electron transfer flavoprotein
K04M5_38830	ENOG4107QSN	dihydrolipoamide acetyltransferase
K04M5_38850	ENOG4107RUY	(E1 component), alpha subunit
K04M5_38890	ENOG4105R8A	Heat shock protein
K04M5_38900	ENOG4106E5D	Protein of unknown function (DUF461)
K04M5_38950	ENOG4105ETX	regulatoR
K04M5_39010	ENOG4105BZU	Histidine kinase
K04M5_39030	ENOG4105C44	Serine transporter
K04M5_39110	ENOG4105DG7	nitrate ABC transporter
K04M5_39120	ENOG4105D7T	ABC transporter
K04M5_39130	ENOG4107QZF	nitrite reductase NADPH large subunit
K04M5_39190	ENOG4105F8J	Adenylate Guanylate cyclase
K04M5_39230	ENOG4105D9P	serine threonine protein kinase
K04M5_39270	ENOG4106VK6	Flagellar motor protein
K04M5_39300	ENOG4108ZF3	Phosphatase
K04M5_39390	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
K04M5_39440	ENOG4107RFY	SbcCD D subunit
K04M5_39450	ENOG4105EYH	Exonuclease
K04M5_39470	ENOG4105QNF	Outer membrane lipoprotein
K04M5_39490	ENOG4105CSX	c4-dicarboxylate anaerobic carrier
K04M5_39510	ENOG4105C5W	Aldolase
K04M5_39530	ENOG4107R4Q	Functions as an ATPase. May play a role in metal insertion (metal-chelatase) or as a chaperone (By similarity)
K04M5_39540	ENOG4105EV2	VWA domain protein interacting with AAA ATPase
K04M5_39570	ENOG4105CC0	LysR family Transcriptional regulator
K04M5_39580	ENOG4105CXG	d-lactate dehydrogenase
K04M5_39610	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
K04M5_39620	ENOG4108NVR	Methyl-accepting chemotaxis
K04M5_39770	ENOG41087GE	Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate (By similarity)
K04M5_39780	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
K04M5_39800	ENOG4108RDD	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity)
K04M5_40230	ENOG4105DEN	Luciferase family
K04M5_40240	ENOG4105BZU	Histidine kinase
K04M5_40260	ENOG4105BZU	Histidine kinase
K04M5_40270	ENOG4105NXH	GreA GreB family elongation factor
K04M5_40290	ENOG4107QZF	nitrite reductase NADPH large subunit
K04M5_40300	ENOG4105WZK	nitrite reductase NADPH small subunit
K04M5_40310	ENOG4105TMB	Formate nitrite transporter
K04M5_40320	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
K04M5_40350	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
K04M5_40390	ENOG4105KNA	-acetyltransferase
K04M5_40400	ENOG4105VXR	cytoplasmic protein
K04M5_40410	ENOG4108ISG	Major Facilitator
K04M5_40420	ENOG4105K63	Thioredoxin
K04M5_40430	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
K04M5_40470	ENOG4105EIP	mannose-6-phosphate isomerase
K04M5_40480	ENOG4105CXY	transporter
K04M5_40490	ENOG4105BZU	Histidine kinase
K04M5_40500	ENOG4108KX4	response regulator
K04M5_40510	ENOG4105CXY	transporter
K04M5_40520	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
K04M5_40530	ENOG4105C5Q	Transcriptional regulator
K04M5_40540	ENOG4107QKC	Oxidoreductase alpha (molybdopterin) subunit
K04M5_40570	ENOG4107TIF	Phenazine biosynthesis protein, PhzF family
K04M5_40640	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
K04M5_40650	ENOG4108RDD	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity)
K04M5_40660	ENOG4105UQX	Mate efflux family protein
K04M5_40670	ENOG4108K01	transcriptional regulator
K04M5_40680	ENOG4105CGF	Aromatic amino acid aminotransferase
K04M5_40690	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
K04M5_40710	ENOG4105WXI	Bacterial OB fold (BOF) protein
K04M5_40720	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
K04M5_40730	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
K04M5_40740	ENOG4105E0C	molybdate abc transporter
K04M5_40750	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
K04M5_40780	ENOG4105BZU	Histidine kinase
K04M5_40810	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
K04M5_40820	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
K04M5_40880	ENOG4108M6U	Universal stress protein A
K04M5_40900	ENOG4105EJC	lysr family transcriptional regulator
K04M5_41220	ENOG4105MQ5	zona occludens toxin
K04M5_41320	ENOG4108ZJT	translation initiation factor, Sui1
K04M5_41340	ENOG4105CPF	Cell wall formation (By similarity)
K04M5_41360	ENOG4105CD5	CoA-binding domain protein
K04M5_41370	ENOG4105CWB	LysR family transcriptional Regulator
K04M5_41390	ENOG4105CMR	udp-glucose 4-epimerase
K04M5_41400	ENOG4105BZU	Histidine kinase
K04M5_41410	ENOG4105E7W	lamb ycsf family protein
K04M5_41420	ENOG4105P4J	Allophanate hydrolase, subunit 1
K04M5_41430	ENOG4107R7A	Allophanate hydrolase subunit 2
K04M5_41450	ENOG4105CV6	ABC transporter, permease
K04M5_41460	ENOG4108I0Y	(ABC) transporter
K04M5_41480	ENOG4105RKW	reductase (By
K04M5_41490	ENOG4105BZU	Histidine kinase
K04M5_41560	ENOG4105KNR	Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity)
K04M5_41580	ENOG4105KA0	thioesterase Superfamily protein
K04M5_41610	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
K04M5_41620	ENOG4108M0H	Extracellular lipase
K04M5_41660	ENOG4105DU1	integral membrane protein, terc
K04M5_41670	ENOG4105CGH	5'-nucleotidase
K04M5_41680	ENOG4105CPB	ATP-dependent endonuclease of the OLD family
K04M5_41690	ENOG4108UQ5	membrane protein YcdZ
K04M5_41700	ENOG4105DUM	transcriptional regulator, lysR family
K04M5_41720	ENOG4105TMB	Formate nitrite transporter
K04M5_41730	ENOG4108YYC	ycei family
K04M5_41740	ENOG4105DS1	cytochrome b561
K04M5_41780	ENOG4105C1J	atp-dependent rna helicase
K04M5_41790	ENOG4108ZYK	Acyl carrier protein phosphodiesterase
K04M5_41810	ENOG4108N3W	hemolysin secretion protein
K04M5_41820	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
K04M5_41850	ENOG4107RE1	Inosine-guanosine kinase
K04M5_41860	ENOG4105CKU	formyltetrahydrofolate synthetase
K04M5_41870	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
K04M5_41890	ENOG4105CF7	AraC family transcriptional regulator
K04M5_41900	ENOG4108I6A	alcohol dehydrogenase
K04M5_41920	ENOG4105CDA	abc transporter atp-binding protein
K04M5_41930	ENOG4105E5Q	amino acid AbC transporter
K04M5_41940	ENOG4106TNF	Periplasmic binding protein
K04M5_41950	ENOG4105DRP	amino acid AbC transporter
K04M5_41960	ENOG4108NJZ	Sensory box GGDEF EAL domain protein
K04M5_41990	ENOG4107B7Y	DNA-binding transcriptional regulator FruR
K04M5_42000	ENOG4105DTZ	bifunctional PTS system fructose-specific transporter subunit IIA HPr protein
K04M5_42010	ENOG4105DE4	1-phosphofructokinase
K04M5_42020	ENOG4105DM4	PTS System
K04M5_42080	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
K04M5_42100	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
K04M5_42110	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
K04M5_42120	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
K04M5_42130	ENOG4108ZI4	Glyoxalase Bleomycin resistance protein (Dioxygenase
K04M5_42140	ENOG4108JMX	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
K04M5_42150	ENOG4105EJC	lysr family transcriptional regulator
K04M5_42160	ENOG4108IPJ	Membrane
K04M5_42170	ENOG4105MDH	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
K04M5_42230	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
K04M5_42310	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
K04M5_42370	ENOG4105CJW	magnesium transporter
K04M5_42410	ENOG4108UYE	Lactoylglutathione lyase
K04M5_42420	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
K04M5_42440	ENOG4105EXC	Acyl-transferase
K04M5_42470	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
K04M5_42480	ENOG4105CBC	glutamate synthase
K04M5_42500	ENOG4107RGH	Aldehyde dehydrogenase
K04M5_42530	ENOG4108I0N	Transporter, RarD family, DMT superfamily protein
K04M5_42580	ENOG4105FR1	rard protein
K04M5_42600	ENOG4108VAU	general secretion pathway protein G
K04M5_42610	ENOG4107R88	Chemotaxis protein (CheV)
K04M5_42620	ENOG4108WQH	regulatoR
K04M5_42640	ENOG4105BZU	Histidine kinase
K04M5_42650	ENOG4105WH1	Two component transcriptional regulator luxr family
K04M5_42660	ENOG4105BZU	Histidine kinase
K04M5_42670	ENOG4105BZU	Histidine kinase
K04M5_42680	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
K04M5_42690	ENOG4107KBT	8-Amino-7-oxononanoate synthase
K04M5_42700	ENOG4108MGY	Histidine kinase
K04M5_42740	ENOG4105CEE	C4-dicarboxylate transporter
K04M5_42770	ENOG4105F2V	VRR-NUC domain-containing protein
K04M5_42790	ENOG4108YDI	single-species biofilm formation on inanimate substrate
K04M5_42800	ENOG4107TE5	Lipid kinase
K04M5_42810	ENOG41064T2	transcriptional regulator, lysR family
K04M5_42820	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
K04M5_42880	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
K04M5_42890	ENOG4105C4X	radical SAM domain protein
K04M5_42900	ENOG41061MV	Arylsulfatase
K04M5_42920	ENOG4105ENH	Sulfatase
K04M5_42930	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
K04M5_42960	ENOG4105BZU	Histidine kinase
K04M5_42970	ENOG4108SV3	Tmao reductase system periplasmic protein tort
K04M5_42980	ENOG4108Z5K	methylglyoxal synthase
K04M5_42990	ENOG41088T4	Helicase IV
K04M5_43000	ENOG4105EM2	membrane
K04M5_43080	ENOG4108Z6Z	Transcriptional regulator
K04M5_43090	ENOG4108IPW	abc transporter atp-binding protein
K04M5_43100	ENOG4105CM4	permease protein
K04M5_43110	ENOG4105DHS	permease protein
K04M5_43140	ENOG4108I5U	Uridine phosphorylase
K04M5_43150	ENOG4106Z1T	Nicotinamide Mononucleotide Transporter
K04M5_43170	ENOG4105ETE	Transcriptional regulator (LacI family
K04M5_43180	ENOG4108RVA	ribokinase
K04M5_43190	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
K04M5_43200	ENOG4105CNN	ABC, transporter
K04M5_43210	ENOG4105C2J	ABC transporter
K04M5_43220	ENOG4105MRB	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity)
K04M5_43230	ENOG4108K0B	C-di-gmp phosphodiesterase
K04M5_43330	ENOG4105D82	Glutamate dehydrogenase
K04M5_43350	ENOG4105BZU	Histidine kinase
K04M5_43360	ENOG4105CA0	peroxidase
K04M5_43380	ENOG4107QX8	SPFH domain, Band 7 family protein
K04M5_43400	ENOG4108RCM	Nitroreductase
K04M5_43410	ENOG4108IJ7	Glycine betaine
K04M5_43420	ENOG4108HQS	Glycine betaine
K04M5_43440	ENOG4105CZ6	Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine (By similarity)
K04M5_43450	ENOG4105C26	Dehydrogenase
K04M5_43460	ENOG4108MHR	Repressor involved in choline regulation of the bet genes (By similarity)
K04M5_43470	ENOG4105BZU	Histidine kinase
K04M5_43490	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
K04M5_43510	ENOG4105E39	Enoyl-CoA hydratase
K04M5_43520	ENOG4105C1G	acyl-Coa dehydrogenase
K04M5_43530	ENOG4105C26	Dehydrogenase
K04M5_43540	ENOG4105CHU	acetyl-coa acetyltransferase
K04M5_43560	ENOG4105C1G	acyl-Coa dehydrogenase
K04M5_43570	ENOG4107QX3	carboxylase
K04M5_43580	ENOG4108IPT	Naphthoate synthase
K04M5_43600	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
K04M5_43620	ENOG4105EGS	Mechanosensitive ion channel
K04M5_43630	ENOG4108UW5	maltose o-acetyltransferase
K04M5_43640	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
K04M5_43650	ENOG4105C4M	(Ubiquinol oxidase) subunit I
K04M5_43660	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
K04M5_43680	ENOG4108S58	Phenazine biosynthesis protein PhzF
K04M5_43720	ENOG4107FQX	Alpha-acetolactate decarboxylase
K04M5_43730	ENOG4105C7K	acetolactate synthase
K04M5_43750	ENOG4105FQ6	thiopurine methyltransferase
K04M5_43760	ENOG4105DZS	Phenylacetate-CoA ligase
K04M5_43770	ENOG4108IV0	ABC, transporter
K04M5_43810	ENOG4108IQE	Amp-dependent synthetase and ligase
K04M5_43820	ENOG4105C0Z	ABC transporter
K04M5_43830	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
K04M5_43840	ENOG4105BZJ	Electron transfer flavoprotein
K04M5_43850	ENOG4105C10	Electron transfer flavoprotein
K04M5_43860	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
K04M5_43870	ENOG4105CI1	PTS System
K04M5_43880	ENOG4105F8D	glycoside hydrolase family 4
K04M5_43890	ENOG4105FDP	GntR family transcriptional regulator
K04M5_43900	ENOG4105KJM	monovalent cation h antiporter subunit g
K04M5_43910	ENOG41080TA	Multiple resistance and ph regulation protein f
K04M5_43920	ENOG4105SC1	monovalent cation H antiporter subunit E
K04M5_43930	ENOG4108JPZ	Monovalent cation H antiporter subunit D
K04M5_43940	ENOG4108ZE9	Monovalent cation H antiporter subunit C
K04M5_43950	ENOG4105D65	subunit l
K04M5_43970	ENOG4105Q9Y	Universal stress protein
K04M5_43980	ENOG4105EMU	Dehydrogenase
K04M5_43990	ENOG4105HEI	LysR family (Transcriptional regulator
K04M5_44010	ENOG4105C2C	drug resistance transporter, Bcr CflA
K04M5_44140	ENOG4105EW9	transcriptional regulator AsnC family
K04M5_44210	ENOG4105D9P	serine threonine protein kinase
K04M5_44260	ENOG4105CS6	Rhs element vgr protein
K04M5_44270	ENOG4108WC9	type VI secretion system effector, hcp1 family
K04M5_44280	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
K04M5_44290	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
K04M5_44340	ENOG4105DR5	peptidase
K04M5_44370	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
K04M5_44470	ENOG4107QHE	Choloylglycine hydrolase
K04M5_44480	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
K04M5_44490	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
K04M5_44510	ENOG4108UNF	response regulator
K04M5_44520	ENOG4107RGM	aldo keto reductase
K04M5_44550	ENOG4105CMQ	Chloride channel
K04M5_44570	ENOG4105EUJ	GTP cyclohydrolase i
K04M5_44580	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
K04M5_44590	ENOG4105D06	uba thif-type nad fad binding protein
K04M5_44620	ENOG4105KHC	sulfurtransferase
K04M5_44640	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
K04M5_44650	ENOG4105CV1	Transketolase (EC 2.2.1.1)
K04M5_44660	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
K04M5_44670	ENOG4105DXI	Major Facilitator superfamily
K04M5_44680	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
K04M5_44690	ENOG4105UYK	outer membrane protein a
K04M5_44700	ENOG4107VXZ	Hydrolase
K04M5_44710	ENOG4108YZN	class I peptide chain release factor
K04M5_44720	ENOG4108N3W	hemolysin secretion protein
K04M5_44750	ENOG4107YWA	deoxycytidylate deaminase
K04M5_44760	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
K04M5_44790	ENOG4105WH1	Two component transcriptional regulator luxr family
K04M5_44800	ENOG4105BZU	Histidine kinase
K04M5_44830	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
K04M5_44870	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
K04M5_44890	ENOG4105CHU	acetyl-coa acetyltransferase
K04M5_44930	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
K04M5_44940	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
K04M5_44990	ENOG4105EW9	transcriptional regulator AsnC family
K04M5_45030	ENOG4105J12	Multidrug resistance protein mdtN
K04M5_45040	ENOG4108US0	Transcription regulator that can specifically activate or repress expression of target genes (By similarity)
K04M5_45050	ENOG4105BZU	Histidine kinase
K04M5_45060	ENOG4108QGH	periplasmic
K04M5_45070	ENOG41082IR	Excinuclease ABC C subunit domain protein
K04M5_45080	ENOG4108YXG	UPF0502 protein
K04M5_45100	ENOG41090HJ	UPF0265 protein
K04M5_45120	ENOG4105BZU	Histidine kinase
K04M5_45180	ENOG4105DUM	transcriptional regulator, lysR family
K04M5_45200	ENOG4105DVH	amino acid
K04M5_45230	ENOG4105E0F	Histidine kinase
K04M5_45240	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
K04M5_45290	ENOG4105J12	Multidrug resistance protein mdtN
K04M5_45300	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
K04M5_45310	ENOG4105CJW	magnesium transporter
K04M5_45320	ENOG4105DQW	permease for cytosine purines, uracil, thiamine, allantoin
K04M5_45330	ENOG4105DZC	cytosine deaminase
K04M5_45340	ENOG4105EST	Metal Dependent Phosphohydrolase
K04M5_45360	ENOG4108J8Q	Catalyzes the facilitated diffusion of 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) into the cell (By similarity)
K04M5_45380	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
K04M5_45420	ENOG4108Z33	Thiol disulfide Interchange Protein
K04M5_45450	ENOG4107EXC	regulatoR
K04M5_45460	ENOG4105E0F	Histidine kinase
K04M5_45480	ENOG41080IJ	Diacylglycerol kinase
K04M5_45490	ENOG4105DIJ	Phosphoethanolamine transferase
K04M5_45500	ENOG4105EP9	oxidoreductase
K04M5_45530	ENOG4108NRW	Phospholipase, patatin family
K04M5_45540	ENOG4105EUB	pirin domain protein
K04M5_45550	ENOG4105VEQ	Cold shock protein
K04M5_45580	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
K04M5_45590	ENOG4105EHV	domain protein
K04M5_45610	ENOG4105DZ1	carboxypeptidase
K04M5_45630	ENOG4105CYM	Glutathione S-transferase
K04M5_45640	ENOG4108HKT	sucrose-6-phosphate hydrolase
K04M5_45650	ENOG4105D7K	pfkb domain protein
K04M5_45660	ENOG4105C5Y	PTS System
K04M5_45700	ENOG4105CHR	reductase
K04M5_45730	ENOG4108P3C	
K04M5_45760	ENOG4105E1F	short-chain dehydrogenase reductase
K04M5_45770	ENOG4105HEI	LysR family (Transcriptional regulator
K04M5_45780	ENOG410874W	AraC family transcriptional regulator
K04M5_45790	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
K04M5_45830	ENOG4105C1J	atp-dependent rna helicase
K04M5_45850	ENOG4107RSM	transcriptional regulator
K04M5_45880	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
K04M5_45890	ENOG4105CPQ	Dehydrogenase
K04M5_45910	ENOG4105CHR	reductase
K04M5_45930	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
K04M5_45940	ENOG4105ENR	peptidase, M24
K04M5_45950	ENOG4105E5N	succinylglutamate desuccinylase aspartoacylase
K04M5_45960	ENOG4108RYR	transcriptional regulator AsnC family
K04M5_45970	ENOG4105C26	Dehydrogenase
K04M5_45980	ENOG4105C8Y	Acetylornithine aminotransferase
K04M5_45990	ENOG4105IUQ	nucleoprotein polynucleotide-associated enzyme
K04M5_46030	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
K04M5_46040	ENOG4105HDK	L-asparaginase
K04M5_46050	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
K04M5_46080	ENOG4105WH1	Two component transcriptional regulator luxr family
K04M5_46090	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
K04M5_46100	ENOG4107RUE	extracellular solute-binding protein family 1
K04M5_46200	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
K04M5_46240	ENOG4105BZS	acriflavin resistance protein
K04M5_46300	ENOG4107RZC	phospholipase d
K04M5_46350	ENOG4108Z4X	TRANSCRIPTIONal
K04M5_46370	ENOG4105RQF	LysR family Transcriptional regulator
K04M5_46390	ENOG4107S8C	mandelate racemase muconate lactonizing
K04M5_46400	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
K04M5_46450	ENOG4105VYW	UPF0251 protein
K04M5_46460	ENOG4107U14	binding-protein-dependent transport systems inner membrane Component
K04M5_46470	ENOG4108IJ7	Glycine betaine
K04M5_46480	ENOG4107EII	Lipoprotein involved with copper homeostasis and adhesion
K04M5_46490	ENOG4105RW8	MltA-interacting MipA family protein
K04M5_46520	ENOG4105ETT	transcriptional Regulator, LysR family
K04M5_46570	ENOG4107RH7	Nicotinate phosphoribosyltransferase
K04M5_46590	ENOG4108RWI	nicotinamidase
K04M5_46620	ENOG4105N2W	Transcriptional regulator
K04M5_46630	ENOG4108F19	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
K04M5_46640	ENOG4105EA8	2-Nitropropane dioxygenase
K04M5_46650	ENOG4105CUB	amino acid
K04M5_46660	ENOG4107FQ9	ethanolamine ammonia-lyase
K04M5_46670	ENOG4105CPD	ethanolamine ammonia-lyase
K04M5_46680	ENOG4108K3Z	AraC family transcriptional regulator
K04M5_46690	ENOG4107Z3H	Transcriptional regulator, TetR family
K04M5_46730	ENOG4105N14	lysine exporter protein LysE YggA
K04M5_46750	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
K04M5_46760	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
K04M5_46770	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
K04M5_46800	ENOG4106UJV	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity)
K04M5_46840	ENOG4105DTJ	flagellar hook-associated protein
K04M5_46850	ENOG4105E1Q	flagellar hook-associated protein
K04M5_46860	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
K04M5_46870	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
K04M5_46880	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
K04M5_46890	ENOG4105CGA	flagellar basal-body rod protein FlgG
K04M5_46900	ENOG4108KPB	Flagellar basal-body rod protein FlgF
K04M5_46910	ENOG4105BZE	flagellar hook protein, FlgE
K04M5_46920	ENOG4105W00	Flagellar hook capping protein
K04M5_46930	ENOG4108ZC9	flagellar basal-body rod protein flgc
K04M5_46940	ENOG4105Q75	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
K04M5_46980	ENOG4105E4C	Lytic transglycosylase catalytic
K04M5_46990	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
K04M5_47030	ENOG4105EJQ	L-serine dehydratase
K04M5_47060	ENOG4105ETT	transcriptional Regulator, LysR family
K04M5_47070	ENOG4105UYK	outer membrane protein a
K04M5_47090	ENOG4105CJP	fad dependent oxidoreductase
K04M5_47110	ENOG4108MJ5	VirK protein
K04M5_47150	ENOG4107RCV	ABC transporter, permease
K04M5_47190	ENOG4107STF	Involved in phosphonate degradation (By similarity)
K04M5_47200	ENOG4108JPW	Aminotransferase
K04M5_47210	ENOG4108KAZ	Involved in phosphonate degradation (By similarity)
K04M5_47220	ENOG4105ETE	Transcriptional regulator (LacI family
K04M5_47270	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
K04M5_47280	ENOG4105KUU	lipolytic protein G-D-S-L family
K04M5_47290	ENOG4105MKU	Transcriptional regulator
K04M5_47320	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
K04M5_47330	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
K04M5_47340	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
K04M5_47350	ENOG4108UHE	carbonic anhydrase
K04M5_47360	ENOG4108UUE	Transcriptional regulator
K04M5_47390	ENOG4105PAD	Hydrolase
K04M5_47400	ENOG4105JQN	Transcriptional regulator
K04M5_47460	ENOG4108UW5	maltose o-acetyltransferase
K04M5_47470	ENOG4108UKZ	OsmC family
K04M5_47480	ENOG4105E0X	reductase
K04M5_47500	ENOG4105EXX	Deoxyribodipyrimidine photolyase-related protein
K04M5_47510	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
K04M5_47520	ENOG4106TD9	Diguanylate cyclase
K04M5_47550	ENOG4105BZU	Histidine kinase
K04M5_47580	ENOG4105D9N	nucleoside
K04M5_47610	ENOG4105C0F	tryptophanase EC 4.1.99.1
K04M5_47630	ENOG4108J5C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
K04M5_47640	ENOG4105C4M	(Ubiquinol oxidase) subunit I
K04M5_47650	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
K04M5_47680	ENOG4105NVB	glycoside hydrolase, family 19
K04M5_47690	ENOG4105D5U	fad dependent oxidoreductase
K04M5_47730	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
K04M5_47740	ENOG4105BZU	Histidine kinase
K04M5_47750	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
K04M5_47800	ENOG4105DUM	transcriptional regulator, lysR family
K04M5_47840	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
K04M5_47850	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
K04M5_47870	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
K04M5_47880	ENOG4105CYW	agmatinase
K04M5_47890	ENOG4105E5M	Multidrug resistance protein D
K04M5_47900	ENOG4105CUG	Oligopeptidase b
K04M5_47930	ENOG4105CC5	ABC transporter
K04M5_47940	ENOG4105DIK	(ABC) transporter
K04M5_47950	ENOG4105DSE	periplasmic solute binding protein
K04M5_48030	ENOG4109015	Biopolymer transport protein exbD tolR
K04M5_48080	ENOG410804D	Sensor Signal Transduction Histidine Kinase
K04M5_48090	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
K04M5_48100	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
K04M5_48120	ENOG4105C5I	Dehydrogenase
K04M5_48130	ENOG4108YYI	Protein of unknown function (DUF2810)
K04M5_48240	ENOG4108TEM	pseudouridine methyltransferase
K04M5_48270	ENOG4105DWF	phosphomethylpyrimidine kinase
K04M5_48280	ENOG4108YI8	ABC transporter
K04M5_48290	ENOG4105Y36	Binding-protein-dependent transport systems, inner membrane component
K04M5_48300	ENOG4107Z6I	Thiamine biosynthesis protein
K04M5_48310	ENOG4105ETU	transcriptional activator (TenA
K04M5_48320	ENOG4105C4U	4-methyl-5-beta-hydroxyethylthiazole kinase
K04M5_48330	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
K04M5_48350	ENOG4107QY8	reductase
K04M5_48360	ENOG4105CUW	cytochrome C-TYPE protein
K04M5_48370	ENOG41068WN	
K04M5_48380	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
K04M5_48450	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
K04M5_48460	ENOG4105BZW	Glycerate kinase
K04M5_48470	ENOG4105C6Z	Gluconate
K04M5_48480	ENOG4108IXP	Carbohydrate diacid transcriptional activator CdaR
K04M5_48550	ENOG4109025	Glyoxalase Bleomycin resistance protein (Dioxygenase
K04M5_48590	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
K04M5_48610	ENOG4105EIF	outer membrane protein W
K04M5_48630	ENOG4107W31	Pentapeptide repeat protein
K04M5_48670	ENOG4105EW9	transcriptional regulator AsnC family
K04M5_48690	ENOG4105Q26	Siderophore-interacting protein
K04M5_48700	ENOG4105CC0	LysR family Transcriptional regulator
K04M5_48710	ENOG4108MUX	N-hydroxyarylamine O-acetyltransferase
K04M5_48730	ENOG4105C4W	S-formylglutathione hydrolase
K04M5_48770	ENOG4108KHX	Diguanylate cyclase
K04M5_48790	ENOG4108HCJ	Hydrolase
K04M5_48800	ENOG4105EJC	lysr family transcriptional regulator
K04M5_48830	ENOG4105D3G	Pseudouridine synthase
K04M5_48840	ENOG4105UQX	Mate efflux family protein
K04M5_48850	ENOG4108K0B	C-di-gmp phosphodiesterase
K04M5_48870	ENOG4105NBK	UPF0345 protein
K04M5_48900	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
K04M5_48940	ENOG4105DN9	Na H antiporter
K04M5_48980	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
K04M5_48990	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
K04M5_49010	ENOG4108VGI	doxx family
K04M5_49020	ENOG4105C2I	pirin domain protein
K04M5_49060	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
K04M5_49080	ENOG4105D6U	Sodium Glutamate Symporter
K04M5_49090	ENOG4107U9B	transcriptional regulator
K04M5_49100	ENOG4105CZV	ABC transporter
K04M5_49120	ENOG4105D6U	Sodium Glutamate Symporter
K04M5_49150	ENOG4105C8Q	Methyl-accepting chemotaxis
K04M5_49160	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
K04M5_49180	ENOG4108VAC	response regulator
K04M5_49190	ENOG4108HRK	Histidine kinase
K04M5_49250	ENOG4105CNI	cell division protein FtsW
K04M5_49260	ENOG4105CDY	transcriptional regulatory protein
K04M5_49280	ENOG4105BZU	Histidine kinase
K04M5_49330	ENOG4108JQ7	(ABC) transporter
K04M5_50510	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
K04M5_50740	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
K04M5_50850	ENOG4107QHF	type ii secretion system protein e
K04M5_50950	ENOG4107QHF	type ii secretion system protein e
K04M5_51320	ENOG4105BZU	Histidine kinase
K04M5_51790	ENOG4105EPW	hflc protein
K04M5_51800	ENOG4107QJR	hflk protein
K04M5_51830	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
K04M5_52130	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)