locus-tag	class	description
K09K1_00020	COG4128	Pfam Zonular occludens toxin
K09K1_00140	COG4128	Pfam Zonular occludens toxin
K09K1_00260	COG4128	Pfam Zonular occludens toxin
K09K1_00360	COG0023	Translation Initiation Factor
K09K1_00380	COG1181	Belongs to the D-alanine--D-alanine ligase family
K09K1_00400	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K09K1_00400	COG1042	CoA-binding domain protein
K09K1_00400	COG0045	succinate-CoA ligase (ADP-forming) activity
K09K1_00410	COG0583	DNA-binding transcription factor activity
K09K1_00440	COG5002	protein histidine kinase activity
K09K1_00440	COG5001	Diguanylate cyclase
K09K1_00440	COG3447	MASE1 domain protein
K09K1_00450	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
K09K1_00460	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
K09K1_00470	COG1984	allophanate hydrolase subunit 2
K09K1_00490	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
K09K1_00500	COG4181	ATPase activity
K09K1_00520	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
K09K1_00530	COG5001	Diguanylate cyclase
K09K1_00530	COG3300	MHYT domain
K09K1_00600	COG4533	DNA binding
K09K1_00620	COG2050	protein possibly involved in aromatic compounds catabolism
K09K1_00650	COG2067	long-chain fatty acid transport protein
K09K1_00660	COG2267	carboxylic ester hydrolase activity
K09K1_00700	COG0861	Integral membrane protein TerC family
K09K1_00710	COG0737	Belongs to the 5'-nucleotidase family
K09K1_00720	COG3593	DNA synthesis involved in DNA repair
K09K1_00740	COG0583	DNA-binding transcription factor activity
K09K1_00760	COG2116	formate transmembrane transporter activity
K09K1_00770	COG2353	YceI-like domain
K09K1_00780	COG3038	cytochrome b561
K09K1_00820	COG0513	Belongs to the DEAD box helicase family
K09K1_00830	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
K09K1_00850	COG0840	transmembrane signaling receptor activity
K09K1_00860	COG0546	phosphoglycolate phosphatase activity
K09K1_00890	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
K09K1_00900	COG2759	Belongs to the formate--tetrahydrofolate ligase family
K09K1_00910	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
K09K1_00930	COG2207	Transcriptional regulator
K09K1_00940	COG1979	alcohol dehydrogenase
K09K1_00960	COG1126	abc transporter atp-binding protein
K09K1_00970	COG0765	amino acid transport
K09K1_00980	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
K09K1_00990	COG0765	amino acid transport
K09K1_01000	COG2203	Gaf domain
K09K1_01000	COG2200	EAL domain
K09K1_01000	COG2199	diguanylate cyclase activity
K09K1_01030	COG1609	Transcriptional regulator
K09K1_01040	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
K09K1_01040	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
K09K1_01050	COG1105	Belongs to the carbohydrate kinase PfkB family
K09K1_01060	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
K09K1_01060	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
K09K1_01060	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
K09K1_01120	COG0404	The glycine cleavage system catalyzes the degradation of glycine
K09K1_01140	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
K09K1_01150	COG0509	glycine decarboxylation via glycine cleavage system
K09K1_01170	COG0346	lactoylglutathione lyase activity
K09K1_01180	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K09K1_01190	COG0583	DNA-binding transcription factor activity
K09K1_01200	COG0697	spore germination
K09K1_01210	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
K09K1_01270	COG2176	DNA-directed DNA polymerase activity
K09K1_01350	COG0242	peptide deformylase activity
K09K1_01410	COG2239	Acts as a magnesium transporter
K09K1_01450	COG0346	lactoylglutathione lyase activity
K09K1_01460	COG1902	pentaerythritol trinitrate reductase activity
K09K1_01480	COG2755	lipolytic protein G-D-S-L family
K09K1_01480	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
K09K1_01510	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
K09K1_01520	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
K09K1_01520	COG0069	glutamate synthase activity
K09K1_01580	COG2076	Multidrug Resistance protein
K09K1_01620	COG2962	Rard protein
K09K1_01650	COG0784	Response regulator, receiver
K09K1_01650	COG0835	chemotaxis
K09K1_01660	COG2197	response regulator
K09K1_01680	COG3706	GGDEF domain
K09K1_01690	COG2197	response regulator
K09K1_01700	COG5001	Diguanylate cyclase
K09K1_01700	COG3300	MHYT domain
K09K1_01710	COG0784	Response regulator, receiver
K09K1_01710	COG2205	protein histidine kinase activity
K09K1_01720	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
K09K1_01760	COG0456	acetyltransferase
K09K1_01760	COG1214	PFAM Peptidase M22, glycoprotease
K09K1_01780	COG3069	C4-dicarboxylate transmembrane transporter activity
K09K1_01830	COG3111	PFAM Bacterial OB fold (BOF) protein
K09K1_01840	COG1597	lipid kinase activity
K09K1_01850	COG0583	DNA-binding transcription factor activity
K09K1_01860	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
K09K1_01920	COG0714	Associated with various cellular activities
K09K1_01930	COG0641	radical SAM
K09K1_01940	COG3119	arylsulfatase activity
K09K1_01960	COG3119	arylsulfatase activity
K09K1_01970	COG0745	RESPONSE REGULATOR receiver
K09K1_02000	COG2198	Histidine kinase
K09K1_02000	COG0784	Response regulator, receiver
K09K1_02000	COG2205	protein histidine kinase activity
K09K1_02010	COG1879	ABC-type sugar transport system periplasmic component
K09K1_02020	COG1803	Methylglyoxal synthase
K09K1_02030	COG0210	DNA helicase
K09K1_02040	COG1289	transmembrane transporter activity
K09K1_02110	COG4771	TonB-dependent receptor
K09K1_02110	COG1629	transport
K09K1_02130	COG0789	Transcriptional regulator
K09K1_02140	COG4604	ABC transporter, ATP-binding protein
K09K1_02150	COG4605	iron ion homeostasis
K09K1_02160	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K09K1_02170	COG4607	ABC-type enterochelin transport system periplasmic component
K09K1_02190	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
K09K1_02220	COG1609	Transcriptional regulator
K09K1_02230	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
K09K1_02240	COG1879	ABC-type sugar transport system periplasmic component
K09K1_02250	COG1172	Belongs to the binding-protein-dependent transport system permease family
K09K1_02260	COG1129	ABC transporter
K09K1_02270	COG1869	D-ribose catabolic process
K09K1_02280	COG5001	Diguanylate cyclase
K09K1_02380	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
K09K1_02400	COG2205	protein histidine kinase activity
K09K1_02400	COG0784	Response regulator, receiver
K09K1_02430	COG0330	HflC and HflK could
K09K1_02460	COG4175	Glycine betaine
K09K1_02460	COG0517	IMP dehydrogenase activity
K09K1_02470	COG4176	ABC-type proline glycine betaine transport system permease component
K09K1_02500	COG1012	belongs to the aldehyde dehydrogenase family
K09K1_02510	COG1309	transcriptional regulator
K09K1_02520	COG3706	GGDEF domain
K09K1_02520	COG0745	RESPONSE REGULATOR receiver
K09K1_02530	COG1028	Short-chain dehydrogenase reductase Sdr
K09K1_02560	COG1024	Enoyl-CoA hydratase
K09K1_02570	COG1960	acyl-CoA dehydrogenase activity
K09K1_02590	COG0183	Belongs to the thiolase family
K09K1_02610	COG1960	acyl-CoA dehydrogenase activity
K09K1_02620	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
K09K1_02670	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
K09K1_02670	COG3264	Mechanosensitive ion channel
K09K1_02680	COG0110	maltose O-acetyltransferase activity
K09K1_02690	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K09K1_02700	COG1271	oxidase subunit
K09K1_02710	COG1294	oxidase, subunit
K09K1_02730	COG0384	phenazine biosynthesis protein PhzF
K09K1_02770	COG3527	Alpha-acetolactate decarboxylase
K09K1_02790	COG1028	Short-chain dehydrogenase reductase Sdr
K09K1_02800	COG0500	methyltransferase
K09K1_02860	COG1022	Amp-dependent synthetase and ligase
K09K1_02910	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
K09K1_02920	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
K09K1_02920	COG1263	PTS System
K09K1_02930	COG1486	melibiose metabolic process
K09K1_02940	COG2188	Transcriptional regulator
K09K1_02950	COG1320	monovalent cation:proton antiporter activity
K09K1_02960	COG2212	antiporter activity
K09K1_02990	COG1006	Multisubunit Na H antiporter MnhC subunit
K09K1_03000	COG2111	Na H antiporter
K09K1_03000	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
K09K1_03020	COG0589	response to stress
K09K1_03030	COG4221	oxidoreductase activity
K09K1_03040	COG0583	DNA-binding transcription factor activity
K09K1_03060	COG2814	Major facilitator Superfamily
K09K1_03190	COG1522	sequence-specific DNA binding
K09K1_03260	COG0515	serine threonine protein kinase
K09K1_03310	COG3501	Rhs element vgr protein
K09K1_03340	COG2204	response regulator
K09K1_03400	COG0739	heme binding
K09K1_03430	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K09K1_03530	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
K09K1_03550	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
K09K1_03550	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
K09K1_03580	COG4989	oxidoreductase activity
K09K1_03610	COG0038	chloride channel
K09K1_03680	COG2897	thiosulfate sulfurtransferase activity
K09K1_03700	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
K09K1_03710	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
K09K1_03720	COG0840	transmembrane signaling receptor activity
K09K1_03730	COG2814	Major facilitator Superfamily
K09K1_03740	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
K09K1_03760	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
K09K1_03780	COG0840	transmembrane signaling receptor activity
K09K1_03830	COG2195	Cleaves the N-terminal amino acid of tripeptides
K09K1_03860	COG2197	response regulator
K09K1_03870	COG3850	Histidine kinase
K09K1_03880	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
K09K1_03900	COG0243	molybdopterin cofactor binding
K09K1_03920	COG3005	denitrification pathway
K09K1_03940	COG3243	poly(R)-hydroxyalkanoic acid synthase
K09K1_03960	COG0183	Belongs to the thiolase family
K09K1_03980	COG1280	lysine exporter protein (LysE YggA)
K09K1_04000	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
K09K1_04010	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
K09K1_04110	COG1846	Transcriptional regulator
K09K1_04120	COG0784	Response regulator, receiver
K09K1_04120	COG2205	protein histidine kinase activity
K09K1_04130	COG1879	ABC-type sugar transport system periplasmic component
K09K1_04140	COG2827	Endonuclease containing a URI domain
K09K1_04150	COG3132	Protein of unknown function, DUF480
K09K1_04190	COG5002	protein histidine kinase activity
K09K1_04190	COG2205	protein histidine kinase activity
K09K1_04190	COG0784	Response regulator, receiver
K09K1_04250	COG0583	DNA-binding transcription factor activity
K09K1_04270	COG0531	amino acid
K09K1_04300	COG2205	protein histidine kinase activity
K09K1_04310	COG0745	RESPONSE REGULATOR receiver
K09K1_04370	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
K09K1_04380	COG2239	Acts as a magnesium transporter
K09K1_04390	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
K09K1_04400	COG0402	S-adenosylhomocysteine deaminase activity
K09K1_04410	COG1418	mRNA catabolic process
K09K1_04430	COG2814	Major facilitator Superfamily
K09K1_04450	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
K09K1_04490	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
K09K1_04520	COG0745	RESPONSE REGULATOR receiver
K09K1_04530	COG2205	protein histidine kinase activity
K09K1_04550	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
K09K1_04560	COG2194	sulfuric ester hydrolase activity
K09K1_04600	COG4667	esterase of the alpha-beta hydrolase superfamily
K09K1_04610	COG1741	Belongs to the pirin family
K09K1_04620	COG1278	Cold shock
K09K1_04650	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
K09K1_04660	COG0678	peroxiredoxin activity
K09K1_04660	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
K09K1_04680	COG1686	Belongs to the peptidase S11 family
K09K1_04700	COG0625	glutathione transferase activity
K09K1_04710	COG1621	beta-fructofuranosidase activity
K09K1_04720	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
K09K1_04730	COG1263	PTS System
K09K1_04730	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
K09K1_04770	COG1028	Short-chain dehydrogenase reductase Sdr
K09K1_04800	COG3746	phosphate-selective porin O and P
K09K1_04830	COG0300	oxidoreductase activity
K09K1_04840	COG0583	DNA-binding transcription factor activity
K09K1_04850	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
K09K1_04850	COG2207	Transcriptional regulator
K09K1_04860	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K09K1_04900	COG0513	Belongs to the DEAD box helicase family
K09K1_04920	COG0583	DNA-binding transcription factor activity
K09K1_04950	COG1902	pentaerythritol trinitrate reductase activity
K09K1_04960	COG1063	alcohol dehydrogenase
K09K1_04980	COG1028	Short-chain dehydrogenase reductase Sdr
K09K1_05000	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K09K1_05010	COG0006	proline dipeptidase activity
K09K1_05020	COG3608	succinylglutamate desuccinylase aspartoacylase
K09K1_05030	COG1522	sequence-specific DNA binding
K09K1_05040	COG1012	belongs to the aldehyde dehydrogenase family
K09K1_05050	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
K09K1_05060	COG3122	Protein conserved in bacteria
K09K1_05090	COG0583	DNA-binding transcription factor activity
K09K1_05110	COG0252	asparaginase activity
K09K1_05120	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
K09K1_05150	COG2197	response regulator
K09K1_05160	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
K09K1_05170	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
K09K1_05210	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
K09K1_05270	COG3842	ATPase activity
K09K1_05310	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
K09K1_05370	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
K09K1_05380	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
K09K1_05440	COG0583	DNA-binding transcription factor activity
K09K1_05460	COG4948	Mandelate Racemase Muconate Lactonizing
K09K1_05470	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
K09K1_05520	COG1342	Belongs to the UPF0251 family
K09K1_05530	COG4176	ABC-type proline glycine betaine transport system permease component
K09K1_05540	COG3448	diguanylate cyclase activity
K09K1_05540	COG4175	Glycine betaine
K09K1_05550	COG3015	lipoprotein NlpE involved in copper resistance
K09K1_05560	COG3713	MltA-interacting MipA family protein
K09K1_05590	COG0583	DNA-binding transcription factor activity
K09K1_05640	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
K09K1_05660	COG1335	isochorismatase
K09K1_05690	COG1349	DNA-binding transcription factor activity
K09K1_05710	COG2070	2-Nitropropane dioxygenase
K09K1_05720	COG0531	amino acid
K09K1_05730	COG4302	ethanolamine ammonia-lyase activity
K09K1_05740	COG4303	Ethanolamine ammonia lyase large subunit
K09K1_05760	COG1309	transcriptional regulator
K09K1_05800	COG1280	lysine exporter protein (LysE YggA)
K09K1_05820	COG0459	protein refolding
K09K1_05830	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
K09K1_05840	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
K09K1_05870	COG1304	FMN binding
K09K1_05920	COG4786	Flagellar basal body rod
K09K1_05920	COG1256	bacterial-type flagellum assembly
K09K1_05940	COG1706	bacterial-type flagellum-dependent cell motility
K09K1_05950	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
K09K1_05960	COG4786	Flagellar basal body rod
K09K1_05970	COG4787	bacterial-type flagellum-dependent cell motility
K09K1_05980	COG1749	Flagellar hook protein flgE
K09K1_05990	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
K09K1_06000	COG1558	bacterial-type flagellum-dependent cell motility
K09K1_06010	COG1815	bacterial-type flagellum-dependent cell motility
K09K1_06050	COG0741	lytic transglycosylase activity
K09K1_06060	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
K09K1_06100	COG1760	l-serine dehydratase
K09K1_06130	COG0583	DNA-binding transcription factor activity
K09K1_06150	COG2866	Carboxypeptidase
K09K1_06160	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
K09K1_06180	COG2990	Protein conserved in bacteria
K09K1_06230	COG3842	ATPase activity
K09K1_06250	COG1840	ABC-type Fe3 transport system, periplasmic component
K09K1_06290	COG1609	Transcriptional regulator
K09K1_06350	COG3240	lipase activity
K09K1_06360	COG1309	transcriptional regulator
K09K1_06390	COG0577	efflux transmembrane transporter activity
K09K1_06390	COG1136	(ABC) transporter
K09K1_06400	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
K09K1_06410	COG2067	long-chain fatty acid transport protein
K09K1_06420	COG3338	carbonate dehydratase activity
K09K1_06430	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
K09K1_06460	COG1011	Hydrolase
K09K1_06530	COG0110	maltose O-acetyltransferase activity
K09K1_06540	COG1765	OsmC-like protein
K09K1_06550	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
K09K1_06550	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
K09K1_06570	COG3046	protein related to deoxyribodipyrimidine photolyase
K09K1_06580	COG0415	Belongs to the DNA photolyase family
K09K1_06590	COG3706	GGDEF domain
K09K1_06620	COG3706	GGDEF domain
K09K1_06650	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
K09K1_06680	COG3033	Beta-eliminating lyase
K09K1_06710	COG1271	oxidase subunit
K09K1_06720	COG1294	oxidase, subunit
K09K1_06750	COG3179	chitinase
K09K1_06760	COG0579	oxidoreductase
K09K1_06810	COG3706	GGDEF domain
K09K1_06870	COG0583	DNA-binding transcription factor activity
K09K1_06910	COG0189	ligase activity
K09K1_06920	COG0189	ligase activity
K09K1_06920	COG4067	protein conserved in archaea
K09K1_06940	COG1166	arginine decarboxylase activity
K09K1_06950	COG0010	Belongs to the arginase family
K09K1_06960	COG2814	Major facilitator Superfamily
K09K1_06970	COG1770	oligopeptidase
K09K1_07000	COG1108	ABC-type Mn2 Zn2 transport systems permease components
K09K1_07010	COG1121	(ABC) transporter
K09K1_07020	COG0803	Belongs to the bacterial solute-binding protein 9 family
K09K1_07100	COG0848	biopolymer transport protein
K09K1_07110	COG0811	peptide transport
K09K1_07120	COG0811	peptide transport
K09K1_07160	COG0745	RESPONSE REGULATOR receiver
K09K1_07170	COG0584	glycerophosphoryl diester phosphodiesterase
K09K1_07190	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
K09K1_07320	COG0312	modulator of DNA gyrase
K09K1_07330	COG0312	modulator of DNA gyrase
K09K1_07340	COG0351	phosphomethylpyrimidine kinase
K09K1_07350	COG1116	anion transmembrane transporter activity
K09K1_07360	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
K09K1_07370	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
K09K1_07380	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
K09K1_07420	COG0243	molybdopterin cofactor binding
K09K1_07430	COG3005	denitrification pathway
K09K1_07440	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K09K1_07450	COG1028	Short-chain dehydrogenase reductase Sdr
K09K1_07480	COG0456	acetyltransferase
K09K1_07520	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K09K1_07530	COG1929	Belongs to the glycerate kinase type-1 family
K09K1_07540	COG2610	gluconate transmembrane transporter activity
K09K1_07550	COG3835	regulator
K09K1_07680	COG3047	cAMP biosynthetic process
K09K1_07700	COG1357	PFAM Pentapeptide repeats (8 copies)
K09K1_07760	COG2375	cellular response to nickel ion
K09K1_07770	COG0583	DNA-binding transcription factor activity
K09K1_07780	COG2162	N-hydroxyarylamine O-acetyltransferase activity
K09K1_07790	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
K09K1_07840	COG2199	diguanylate cyclase activity
K09K1_07860	COG0561	phosphatase activity
K09K1_07870	COG0583	DNA-binding transcription factor activity
K09K1_07900	COG0564	pseudouridine synthase activity
K09K1_07910	COG0534	Mate efflux family protein
K09K1_07920	COG5001	Diguanylate cyclase
K09K1_07940	COG3123	guanosine phosphorylase activity
K09K1_07970	COG0596	Alpha beta hydrolase
K09K1_08040	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
K09K1_08060	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
K09K1_08070	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
K09K1_08070	COG2169	Transcriptional regulator
K09K1_08090	COG2259	Doxx family
K09K1_08100	COG1741	Belongs to the pirin family
K09K1_08140	COG0363	glucosamine-6-phosphate deaminase activity
K09K1_08160	COG0786	glutamate:sodium symporter activity
K09K1_08170	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K09K1_08180	COG1131	(ABC) transporter
K09K1_08200	COG0786	glutamate:sodium symporter activity
K09K1_08240	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
K09K1_08260	COG3279	Response regulator of the LytR AlgR family
K09K1_08270	COG3275	phosphorelay sensor kinase activity
K09K1_08330	COG0772	Belongs to the SEDS family
K09K1_08380	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
K09K1_08380	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
K09K1_08400	COG0444	Belongs to the ABC transporter superfamily
K09K1_08410	COG4608	Belongs to the ABC transporter superfamily
K09K1_08460	COG1444	tRNA N-acetyltransferase activity
K09K1_08500	COG3340	Belongs to the peptidase S51 family
K09K1_08510	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
K09K1_08520	COG1263	PTS System
K09K1_08520	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
K09K1_08530	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
K09K1_08560	COG4166	transmembrane transport
K09K1_08660	COG0259	pyridoxamine-phosphate oxidase activity
K09K1_08710	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
K09K1_08790	COG1132	(ABC) transporter
K09K1_08810	COG0513	Belongs to the DEAD box helicase family
K09K1_08820	COG2258	MOSC domain
K09K1_08910	COG3634	alkyl hydroperoxide reductase activity
K09K1_08920	COG0450	alkyl hydroperoxide reductase
K09K1_09010	COG1846	Transcriptional regulator
K09K1_09020	COG1764	response to oxidative stress
K09K1_09100	COG1136	(ABC) transporter
K09K1_09150	COG0745	RESPONSE REGULATOR receiver
K09K1_09170	COG1653	transport
K09K1_09180	COG0019	diaminopimelate decarboxylase activity
K09K1_09190	COG4264	IucA IucC family
K09K1_09240	COG4772	TonB-dependent receptor
K09K1_09250	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
K09K1_09260	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K09K1_09270	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K09K1_09280	COG1120	ATPase activity
K09K1_09290	COG0840	transmembrane signaling receptor activity
K09K1_09300	COG0612	Peptidase, M16
K09K1_09320	COG0739	heme binding
K09K1_09350	COG2814	Major facilitator Superfamily
K09K1_09370	COG1609	Transcriptional regulator
K09K1_09380	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
K09K1_09430	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
K09K1_09440	COG1609	Transcriptional regulator
K09K1_09490	COG0596	Alpha beta hydrolase
K09K1_09540	COG1760	l-serine dehydratase
K09K1_09560	COG4580	involved in the transport of maltose and maltodextrins
K09K1_09600	COG2356	endonuclease I
K09K1_09640	COG1982	Orn Lys Arg decarboxylase major
K09K1_09650	COG0531	amino acid
K09K1_09670	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
K09K1_09680	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
K09K1_09690	COG1162	GTPase activity
K09K1_09700	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
K09K1_09700	COG1263	PTS System
K09K1_09710	COG1999	signal sequence binding
K09K1_09740	COG2909	trisaccharide binding
K09K1_09750	COG0058	SHG alpha-glucan phosphorylase activity
K09K1_09760	COG1640	4-alpha-glucanotransferase
K09K1_09770	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
K09K1_09780	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
K09K1_09790	COG0366	Alpha amylase catalytic
K09K1_09810	COG3366	ferrous iron transmembrane transporter activity
K09K1_09820	COG0700	Nucleoside recognition
K09K1_09830	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
K09K1_09840	COG3339	Conserved Protein
K09K1_09850	COG1301	dicarboxylic acid transport
K09K1_09870	COG0583	DNA-binding transcription factor activity
K09K1_09920	COG1596	polysaccharide export
K09K1_09950	COG2095	MarC family integral membrane protein
K09K1_09960	COG4667	esterase of the alpha-beta hydrolase superfamily
K09K1_09970	COG3397	chitin binding
K09K1_09980	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
K09K1_09990	COG0415	Belongs to the DNA photolyase family
K09K1_10030	COG1686	Belongs to the peptidase S11 family
K09K1_10080	COG0583	DNA-binding transcription factor activity
K09K1_10090	COG4628	conserved protein (DUF2132)
K09K1_10140	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
K09K1_10150	COG0628	permease
K09K1_10200	COG1289	transmembrane transporter activity
K09K1_10230	COG2814	Major facilitator Superfamily
K09K1_10250	COG0454	-acetyltransferase
K09K1_10270	COG0745	RESPONSE REGULATOR receiver
K09K1_10280	COG2205	protein histidine kinase activity
K09K1_10310	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
K09K1_10320	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
K09K1_10400	COG1360	Flagellar Motor Protein
K09K1_10410	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
K09K1_10420	COG1191	sigma factor activity
K09K1_10430	COG1580	Controls the rotational direction of flagella during chemotaxis
K09K1_10460	COG1516	flagellar protein fliS
K09K1_10470	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
K09K1_10490	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
K09K1_10520	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
K09K1_10540	COG1987	bacterial-type flagellum assembly
K09K1_10590	COG2204	response regulator
K09K1_10620	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
K09K1_10730	COG0346	lactoylglutathione lyase activity
K09K1_10780	COG0745	RESPONSE REGULATOR receiver
K09K1_10830	COG5001	Diguanylate cyclase
K09K1_10830	COG3300	MHYT domain
K09K1_10840	COG0156	8-amino-7-oxononanoate synthase activity
K09K1_10850	COG1063	alcohol dehydrogenase
K09K1_10920	COG0668	transmembrane transport
K09K1_10940	COG1304	FMN binding
K09K1_10950	COG1620	l-lactate permease
K09K1_10960	COG0583	DNA-binding transcription factor activity
K09K1_10970	COG1505	serine-type exopeptidase activity
K09K1_10980	COG4172	Belongs to the ABC transporter superfamily
K09K1_11000	COG1067	ATP-dependent peptidase activity
K09K1_11020	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
K09K1_11060	COG1247	-acetyltransferase
K09K1_11070	COG0437	4 iron, 4 sulfur cluster binding
K09K1_11080	COG0348	domain, Protein
K09K1_11120	COG1122	ATPase activity
K09K1_11130	COG4720	Psort location CytoplasmicMembrane, score
K09K1_11140	COG1566	PFAM secretion protein HlyD family protein
K09K1_11160	COG3706	GGDEF domain
K09K1_11190	COG0813	purine-nucleoside phosphorylase activity
K09K1_11200	COG3272	Protein of unknown function (DUF1722)
K09K1_11210	COG0789	Transcriptional regulator
K09K1_11220	COG0415	Belongs to the DNA photolyase family
K09K1_11230	COG1376	ErfK ybiS ycfS ynhG family protein
K09K1_11230	COG1388	LysM domain
K09K1_11250	COG0513	Belongs to the DEAD box helicase family
K09K1_11260	COG1770	oligopeptidase
K09K1_11270	COG4771	TonB-dependent receptor
K09K1_11320	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
K09K1_11330	COG0573	inorganic phosphate transmembrane transporter activity
K09K1_11340	COG0581	inorganic phosphate transmembrane transporter activity
K09K1_11350	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
K09K1_11380	COG2304	oxidoreductase activity
K09K1_11420	COG0714	Associated with various cellular activities
K09K1_11450	COG2197	response regulator
K09K1_11520	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
K09K1_11530	COG1120	ATPase activity
K09K1_11540	COG4774	siderophore transport
K09K1_11550	COG1132	(ABC) transporter
K09K1_11580	COG0569	domain protein
K09K1_11590	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
K09K1_11600	COG0583	DNA-binding transcription factor activity
K09K1_11640	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
K09K1_11650	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
K09K1_11670	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
K09K1_11680	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
K09K1_11740	COG2084	Dehydrogenase
K09K1_11750	COG0753	catalase activity
K09K1_11770	COG2130	NADP-dependent
K09K1_11780	COG1309	transcriptional regulator
K09K1_11870	COG3206	protein involved in exopolysaccharide biosynthesis
K09K1_11870	COG0489	protein tyrosine kinase activity
K09K1_11900	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
K09K1_11910	COG3842	ATPase activity
K09K1_11930	COG1175	transmembrane transport
K09K1_11940	COG3833	ABC-type maltose transport systems, permease component
K09K1_12000	COG2354	Protein conserved in bacteria
K09K1_12010	COG0418	dihydroorotase activity
K09K1_12020	COG0401	homolog of Blt101
K09K1_12030	COG3217	Mosc domain protein beta barrel domain protein
K09K1_12030	COG3217	Mosc domain protein beta barrel domain protein
K09K1_12030	COG0633	Ferredoxin
K09K1_12030	COG0633	Ferredoxin
K09K1_12050	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
K09K1_12130	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
K09K1_12140	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K09K1_12160	COG0848	biopolymer transport protein
K09K1_12170	COG0811	peptide transport
K09K1_12180	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
K09K1_12200	COG3721	Heme iron utilization protein
K09K1_12210	COG0748	coenzyme F420 binding
K09K1_12230	COG0784	Response regulator, receiver
K09K1_12230	COG0835	chemotaxis
K09K1_12240	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
K09K1_12250	COG0534	Mate efflux family protein
K09K1_12260	COG0444	Belongs to the ABC transporter superfamily
K09K1_12270	COG4608	Belongs to the ABC transporter superfamily
K09K1_12280	COG0747	negative chemotaxis
K09K1_12300	COG1349	DNA-binding transcription factor activity
K09K1_12310	COG2084	Dehydrogenase
K09K1_12320	COG3395	kinase activity
K09K1_12330	COG0235	Class ii aldolase
K09K1_12340	COG3622	Belongs to the hyi family
K09K1_12350	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
K09K1_12360	COG2610	gluconate transmembrane transporter activity
K09K1_12400	COG0583	DNA-binding transcription factor activity
K09K1_12410	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
K09K1_12430	COG4934	collagen metabolic process
K09K1_12450	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
K09K1_12460	COG0789	Transcriptional regulator
K09K1_12470	COG0366	Alpha amylase catalytic
K09K1_12510	COG2249	NAD(P)H dehydrogenase (quinone) activity
K09K1_12520	COG0589	response to stress
K09K1_12530	COG0488	(ABC) transporter
K09K1_12540	COG1505	serine-type exopeptidase activity
K09K1_12560	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
K09K1_12580	COG2067	long-chain fatty acid transport protein
K09K1_12600	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K09K1_12650	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
K09K1_12690	COG3383	formate dehydrogenase (NAD+) activity
K09K1_12710	COG0842	Transport permease protein
K09K1_12720	COG1131	(ABC) transporter
K09K1_12760	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
K09K1_12780	COG4145	pantothenate transmembrane transporter activity
K09K1_12790	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
K09K1_12800	COG0800	Aldolase
K09K1_12820	COG2706	6-phosphogluconolactonase activity
K09K1_12830	COG0251	oxidation-reduction process
K09K1_12850	COG1881	PFAM PEBP family protein
K09K1_12870	COG0798	PFAM Bile acid sodium symporter
K09K1_12900	COG1733	regulation of RNA biosynthetic process
K09K1_12960	COG4989	oxidoreductase activity
K09K1_13010	COG0814	amino acid
K09K1_13080	COG0739	heme binding
K09K1_13090	COG5001	Diguanylate cyclase
K09K1_13100	COG0583	DNA-binding transcription factor activity
K09K1_13110	COG2814	Major facilitator Superfamily
K09K1_13150	COG0697	spore germination
K09K1_13180	COG0179	Fumarylacetoacetate (FAA) hydrolase
K09K1_13220	COG1280	lysine exporter protein (LysE YggA)
K09K1_13240	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
K09K1_13250	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
K09K1_13270	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
K09K1_13320	COG1612	heme a metabolic process
K09K1_13330	COG0109	protoheme IX farnesyltransferase activity
K09K1_13340	COG0545	Peptidyl-prolyl cis-trans isomerase
K09K1_13400	COG1278	Cold shock
K09K1_13410	COG3036	rescue of stalled ribosome
K09K1_13420	COG2199	diguanylate cyclase activity
K09K1_13450	COG1132	(ABC) transporter
K09K1_13460	COG1132	(ABC) transporter
K09K1_13470	COG1538	Outer membrane efflux protein
K09K1_13480	COG0784	Response regulator, receiver
K09K1_13480	COG2205	protein histidine kinase activity
K09K1_13530	COG0840	transmembrane signaling receptor activity
K09K1_13550	COG0783	Belongs to the Dps family
K09K1_13570	COG2133	pyrroloquinoline quinone binding
K09K1_13580	COG1454	alcohol dehydrogenase
K09K1_13590	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
K09K1_13640	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
K09K1_13650	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
K09K1_13660	COG3186	Phenylalanine-4-hydroxylase
K09K1_13710	COG3530	Putative quorum-sensing-regulated virulence factor
K09K1_13750	COG0513	Belongs to the DEAD box helicase family
K09K1_13760	COG4628	conserved protein (DUF2132)
K09K1_13780	COG0133	tryptophan synthase activity
K09K1_13790	COG1278	Cold shock
K09K1_13810	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
K09K1_13830	COG0523	cobalamin synthesis protein
K09K1_13840	COG0513	Belongs to the DEAD box helicase family
K09K1_13880	COG2200	EAL domain
K09K1_13890	COG1119	ATPase activity
K09K1_13930	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
K09K1_13960	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
K09K1_13970	COG0513	Belongs to the DEAD box helicase family
K09K1_13980	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
K09K1_14000	COG1073	alpha beta
K09K1_14010	COG1073	alpha beta
K09K1_14040	COG0730	response to heat
K09K1_14070	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
K09K1_14090	COG0523	cobalamin synthesis protein
K09K1_14100	COG2988	succinylglutamate desuccinylase activity
K09K1_14110	COG0739	heme binding
K09K1_14130	COG0523	cobalamin synthesis protein
K09K1_14150	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
K09K1_14160	COG2095	MarC family integral membrane protein
K09K1_14210	COG1024	Enoyl-CoA hydratase
K09K1_14220	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
K09K1_14230	COG1960	acyl-CoA dehydrogenase activity
K09K1_14250	COG0183	Belongs to the thiolase family
K09K1_14280	COG1024	Enoyl-CoA hydratase
K09K1_14290	COG1024	Enoyl-CoA hydratase
K09K1_14310	COG1028	Short-chain dehydrogenase reductase Sdr
K09K1_14320	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
K09K1_14330	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
K09K1_14340	COG1845	cytochrome c oxidase, subunit III
K09K1_14350	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
K09K1_14360	COG0109	protoheme IX farnesyltransferase activity
K09K1_14370	COG1902	pentaerythritol trinitrate reductase activity
K09K1_14370	COG0446	pyridine nucleotide-disulphide oxidoreductase
K09K1_14400	COG1012	belongs to the aldehyde dehydrogenase family
K09K1_14420	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
K09K1_14480	COG1126	abc transporter atp-binding protein
K09K1_14490	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
K09K1_14500	COG4215	(ABC) transporter
K09K1_14510	COG4160	amino acid transport
K09K1_14650	COG0443	Heat shock 70 kDa protein
K09K1_14660	COG2847	Copper chaperone PCu(A)C
K09K1_14780	COG3706	GGDEF domain
K09K1_14800	COG0814	amino acid
K09K1_14820	COG0243	molybdopterin cofactor binding
K09K1_14860	COG3707	response regulator
K09K1_14870	COG1116	anion transmembrane transporter activity
K09K1_14870	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
K09K1_14880	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
K09K1_14890	COG1116	anion transmembrane transporter activity
K09K1_14900	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
K09K1_14900	COG2146	nitrite reductase [NAD(P)H] activity
K09K1_15000	COG2815	serine threonine protein kinase
K09K1_15000	COG0515	serine threonine protein kinase
K09K1_15070	COG0631	protein serine/threonine phosphatase activity
K09K1_15180	COG3501	Rhs element vgr protein
K09K1_15210	COG0420	3'-5' exonuclease activity
K09K1_15220	COG0419	ATPase involved in DNA repair
K09K1_15240	COG3040	lipid binding
K09K1_15260	COG1288	antiporter activity
K09K1_15280	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
K09K1_15310	COG2425	protein containing a von Willebrand factor type A (vWA) domain
K09K1_15340	COG0583	DNA-binding transcription factor activity
K09K1_15350	COG0277	FAD linked oxidase domain protein
K09K1_15380	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
K09K1_15450	COG2176	DNA-directed DNA polymerase activity
K09K1_15540	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
K09K1_15550	COG1328	CTP reductase activity
K09K1_16000	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
K09K1_16040	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
K09K1_16060	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
K09K1_16070	COG2146	nitrite reductase [NAD(P)H] activity
K09K1_16080	COG2116	formate transmembrane transporter activity
K09K1_16120	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
K09K1_16180	COG2814	Major facilitator Superfamily
K09K1_16190	COG3118	belongs to the thioredoxin family
K09K1_16200	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
K09K1_16250	COG2271	Major facilitator Superfamily
K09K1_16260	COG3851	Histidine kinase
K09K1_16270	COG2197	response regulator
K09K1_16290	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
K09K1_16300	COG0583	DNA-binding transcription factor activity
K09K1_16310	COG0243	molybdopterin cofactor binding
K09K1_16340	COG0384	phenazine biosynthesis protein PhzF
K09K1_16350	COG1794	racemase activity, acting on amino acids and derivatives
K09K1_16410	COG1328	CTP reductase activity
K09K1_16420	COG0602	queuosine metabolic process
K09K1_16430	COG0534	Mate efflux family protein
K09K1_16440	COG2207	Transcriptional regulator
K09K1_16460	COG4067	protein conserved in archaea
K09K1_16460	COG0189	ligase activity
K09K1_16480	COG3111	PFAM Bacterial OB fold (BOF) protein
K09K1_16500	COG0725	ABC transporter, periplasmic molybdate-binding protein
K09K1_16510	COG4149	molybdate abc transporter
K09K1_16520	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
K09K1_16540	COG3706	GGDEF domain
K09K1_16540	COG2203	Gaf domain
K09K1_16540	COG4251	negative regulation of phosphorylation
K09K1_16540	COG5001	Diguanylate cyclase
K09K1_16550	COG3706	GGDEF domain
K09K1_16550	COG0745	RESPONSE REGULATOR receiver
K09K1_16580	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
K09K1_16590	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
K09K1_16640	COG3140	Belongs to the UPF0181 family
K09K1_16670	COG0583	DNA-binding transcription factor activity
K09K1_16990	COG4128	Pfam Zonular occludens toxin
K09K1_17290	COG4128	Pfam Zonular occludens toxin
K09K1_17400	COG0784	Response regulator, receiver
K09K1_17400	COG2205	protein histidine kinase activity
K09K1_17430	COG3278	Belongs to the heme-copper respiratory oxidase family
K09K1_17460	COG2010	Cytochrome c
K09K1_17480	COG2217	Heavy metal translocating P-type atpase
K09K1_17510	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
K09K1_17520	COG0589	response to stress
K09K1_17570	COG3842	ATPase activity
K09K1_17580	COG1176	ABC-type spermidine putrescine transport system, permease component I
K09K1_17590	COG1177	transmembrane transport
K09K1_17600	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
K09K1_17610	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
K09K1_17620	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
K09K1_17640	COG0004	ammonium transporteR
K09K1_17690	COG0437	4 iron, 4 sulfur cluster binding
K09K1_17700	COG3383	formate dehydrogenase (NAD+) activity
K09K1_17700	COG0243	molybdopterin cofactor binding
K09K1_17720	COG3381	protein complex oligomerization
K09K1_17760	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
K09K1_17780	COG0488	(ABC) transporter
K09K1_17790	COG4191	Histidine kinase
K09K1_17800	COG2204	response regulator
K09K1_17830	COG3842	ATPase activity
K09K1_17840	COG0746	molybdenum cofactor guanylyltransferase activity
K09K1_17870	COG1940	carbohydrate kinase activity
K09K1_17950	COG0791	NLP P60 protein
K09K1_17970	COG3706	GGDEF domain
K09K1_18010	COG0307	riboflavin synthase, alpha
K09K1_18020	COG0534	Mate efflux family protein
K09K1_18040	COG1793	dna ligase
K09K1_18110	COG2204	response regulator
K09K1_18120	COG0438	transferase activity, transferring glycosyl groups
K09K1_18130	COG0438	transferase activity, transferring glycosyl groups
K09K1_18190	COG0438	transferase activity, transferring glycosyl groups
K09K1_18200	COG1215	transferase activity, transferring glycosyl groups
K09K1_18210	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
K09K1_18230	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
K09K1_18260	COG1643	Atp-dependent helicase
K09K1_18270	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
K09K1_18370	COG0443	Heat shock 70 kDa protein
K09K1_18380	COG0443	Heat shock 70 kDa protein
K09K1_18430	COG0583	DNA-binding transcription factor activity
K09K1_18480	COG1132	(ABC) transporter
K09K1_18500	COG4774	siderophore transport
K09K1_18520	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
K09K1_18530	COG1120	ATPase activity
K09K1_18560	COG0814	amino acid
K09K1_18580	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
K09K1_18600	COG0861	Integral membrane protein TerC family
K09K1_18620	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
K09K1_18630	COG1328	CTP reductase activity
K09K1_18660	COG5001	Diguanylate cyclase
K09K1_18660	COG3300	MHYT domain
K09K1_18690	COG0471	metal ion transport
K09K1_18730	COG0745	RESPONSE REGULATOR receiver
K09K1_18730	COG3706	GGDEF domain
K09K1_18740	COG4702	Belongs to the UPF0303 family
K09K1_18750	COG0673	inositol 2-dehydrogenase activity
K09K1_18760	COG1349	DNA-binding transcription factor activity
K09K1_18790	COG1538	Outer membrane efflux protein
K09K1_18840	COG3119	arylsulfatase activity
K09K1_18870	COG0641	radical SAM
K09K1_18900	COG3119	arylsulfatase activity
K09K1_18910	COG0527	aspartate kinase activity
K09K1_18920	COG0662	Cupin 2, conserved barrel domain protein
K09K1_18930	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
K09K1_18940	COG0456	acetyltransferase
K09K1_18950	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
K09K1_19000	COG4176	ABC-type proline glycine betaine transport system permease component
K09K1_19010	COG2113	Glycine betaine
K09K1_19020	COG1368	sulfuric ester hydrolase activity
K09K1_19070	COG1115	amino acid carrier protein
K09K1_19090	COG1280	lysine exporter protein (LysE YggA)
K09K1_19100	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
K09K1_19350	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
K09K1_19370	COG1560	Kdo2-lipid A biosynthetic process
K09K1_19400	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
K09K1_19410	COG3063	Type IV pilus biogenesis stability protein PilW
K09K1_19490	COG2315	Protein conserved in bacteria
K09K1_19500	COG1846	Transcriptional regulator
K09K1_19520	COG2200	EAL domain
K09K1_19530	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
K09K1_19540	COG1012	belongs to the aldehyde dehydrogenase family
K09K1_19550	COG2957	Belongs to the agmatine deiminase family
K09K1_19570	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
K09K1_19580	COG1012	belongs to the aldehyde dehydrogenase family
K09K1_19590	COG1917	Cupin 2, conserved barrel domain protein
K09K1_19590	COG1396	sequence-specific DNA binding
K09K1_19600	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
K09K1_19610	COG0174	glutamine synthetase
K09K1_19620	COG1757	Na H antiporter
K09K1_19650	COG1742	UPF0060 membrane protein
K09K1_19700	COG3755	Protein conserved in bacteria
K09K1_19800	COG0625	glutathione transferase activity
K09K1_19820	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
K09K1_19840	COG2195	Cleaves the N-terminal amino acid of tripeptides
K09K1_19860	COG0601	transmembrane transport
K09K1_19870	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
K09K1_19880	COG0444	Belongs to the ABC transporter superfamily
K09K1_19910	COG3291	Pkd domain containing protein
K09K1_19930	COG1177	transmembrane transport
K09K1_19940	COG1176	ABC-type spermidine putrescine transport system, permease component I
K09K1_19950	COG3842	ATPase activity
K09K1_19960	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
K09K1_19970	COG2423	ornithine cyclodeaminase activity
K09K1_20000	COG3938	Belongs to the proline racemase family
K09K1_20060	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
K09K1_20070	COG1451	nucleotide metabolic process
K09K1_20090	COG0583	DNA-binding transcription factor activity
K09K1_20130	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
K09K1_20140	COG4139	cobalamin transport
K09K1_20150	COG2988	succinylglutamate desuccinylase activity
K09K1_20190	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
K09K1_20200	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
K09K1_20210	COG0702	epimerase
K09K1_20510	COG1484	DNA-dependent DNA replication
K09K1_20570	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
K09K1_20690	COG2925	Exonuclease
K09K1_20700	COG1380	Effector of murein hydrolase LrgA
K09K1_20710	COG1346	cytolysis
K09K1_20720	COG0295	cytidine deaminase activity
K09K1_20730	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
K09K1_20740	COG0500	methyltransferase
K09K1_20760	COG0776	regulation of translation
K09K1_20780	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
K09K1_20780	COG0072	phenylalanine-tRNA ligase activity
K09K1_20790	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
K09K1_20870	COG0393	Putative heavy-metal-binding
K09K1_20890	COG0291	Belongs to the bacterial ribosomal protein bL35 family
K09K1_20910	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
K09K1_20950	COG1228	amidohydrolase
K09K1_20960	COG0010	Belongs to the arginase family
K09K1_20970	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
K09K1_20980	COG2986	histidine ammonia-lyase
K09K1_21010	COG0247	lactate metabolic process
K09K1_21010	COG0277	FAD linked oxidase domain protein
K09K1_21080	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
K09K1_21110	COG1643	Atp-dependent helicase
K09K1_21120	COG0281	malic enzyme
K09K1_21130	COG2949	membrane
K09K1_21140	COG0471	metal ion transport
K09K1_21150	COG0745	RESPONSE REGULATOR receiver
K09K1_21150	COG3706	GGDEF domain
K09K1_21190	COG0492	ferredoxin-NADP+ reductase activity
K09K1_21200	COG4988	ABC transporter
K09K1_21210	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
K09K1_21230	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
K09K1_21250	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
K09K1_21250	COG4191	Histidine kinase
K09K1_21290	COG3070	regulator of competence-specific genes
K09K1_21310	COG2431	L-lysine efflux transmembrane transporter activity
K09K1_21330	COG0076	glutamate decarboxylase activity
K09K1_21340	COG1737	Transcriptional regulator
K09K1_21370	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
K09K1_21380	COG2985	domain, Protein
K09K1_21380	COG3273	potassium ion transport
K09K1_21390	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
K09K1_21400	COG1960	acyl-CoA dehydrogenase activity
K09K1_21420	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
K09K1_21460	COG0534	Mate efflux family protein
K09K1_21470	COG0702	epimerase
K09K1_21490	COG2814	Major facilitator Superfamily
K09K1_21500	COG1187	pseudouridine synthase activity
K09K1_21510	COG1061	Type III restriction enzyme res subunit
K09K1_21530	COG0745	RESPONSE REGULATOR receiver
K09K1_21540	COG2205	protein histidine kinase activity
K09K1_21550	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
K09K1_21600	COG4134	Bacterial extracellular solute-binding protein
K09K1_21610	COG4135	transport system, permease component
K09K1_21620	COG4136	ATPase activity
K09K1_21630	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
K09K1_21650	COG3604	Transcriptional regulator
K09K1_21660	COG1151	hydroxylamine reductase activity
K09K1_21670	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
K09K1_21690	COG0564	pseudouridine synthase activity
K09K1_21700	COG0733	neurotransmitter:sodium symporter activity
K09K1_21720	COG0626	cystathionine gamma-synthase activity
K09K1_21730	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
K09K1_21740	COG5380	lipid catabolic process
K09K1_21750	COG2818	Glycosylase
K09K1_21790	COG1983	PspC domain protein
K09K1_21810	COG1842	Phage shock protein A
K09K1_21820	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
K09K1_21840	COG4168	peptide transport system, permease
K09K1_21850	COG4171	peptide transport system, permease
K09K1_21870	COG4172	Belongs to the ABC transporter superfamily
K09K1_21890	COG1227	inorganic diphosphatase activity
K09K1_21920	COG0243	molybdopterin cofactor binding
K09K1_21930	COG3005	denitrification pathway
K09K1_21940	COG4459	periplasmic nitrate reductase
K09K1_21950	COG0390	transport system, permease component
K09K1_21970	COG2116	formate transmembrane transporter activity
K09K1_22030	COG1435	thymidine kinase activity
K09K1_22040	COG0215	cysteine-tRNA ligase activity
K09K1_22050	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
K09K1_22060	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
K09K1_22070	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
K09K1_22080	COG3012	SEC-C Motif Domain Protein
K09K1_22090	COG0140	phosphoribosyl-ATP diphosphatase activity
K09K1_22090	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
K09K1_22100	COG0107	imidazoleglycerol-phosphate synthase activity
K09K1_22110	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
K09K1_22120	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
K09K1_22130	COG0131	Imidazoleglycerol-phosphate dehydratase
K09K1_22130	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
K09K1_22150	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
K09K1_22170	COG1757	Na H antiporter
K09K1_22190	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
K09K1_22220	COG2915	High frequency lysogenization protein hflD homolog
K09K1_22230	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
K09K1_22250	COG2268	Band 7 protein
K09K1_22270	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
K09K1_22300	COG0300	oxidoreductase activity
K09K1_22340	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
K09K1_22380	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
K09K1_22390	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
K09K1_22430	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
K09K1_22450	COG1674	ftsk spoiiie
K09K1_22470	COG0686	Belongs to the AlaDH PNT family
K09K1_22490	COG0583	DNA-binding transcription factor activity
K09K1_22540	COG3568	Endonuclease Exonuclease Phosphatase
K09K1_22590	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
K09K1_22600	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
K09K1_22650	COG1271	oxidase subunit
K09K1_22660	COG1294	oxidase, subunit
K09K1_22700	COG5002	protein histidine kinase activity
K09K1_22700	COG0784	Response regulator, receiver
K09K1_22720	COG0754	glutathionylspermidine amidase activity
K09K1_22740	COG3766	membrane
K09K1_22760	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
K09K1_22770	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
K09K1_22780	COG2885	chlorophyll binding
K09K1_22790	COG0823	Involved in the tonB-independent uptake of proteins
K09K1_22820	COG0811	peptide transport
K09K1_22830	COG0824	Thioesterase
K09K1_22850	COG4890	Cyd operon protein YbgT
K09K1_22860	COG1294	oxidase, subunit
K09K1_22870	COG1271	oxidase subunit
K09K1_22880	COG2255	four-way junction helicase activity
K09K1_22890	COG0632	four-way junction helicase activity
K09K1_22900	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
K09K1_22910	COG0217	transcriptional regulatory protein
K09K1_22930	COG1801	Protein of unknown function DUF72
K09K1_22950	COG0500	methyltransferase
K09K1_22960	COG4067	protein conserved in archaea
K09K1_22960	COG0189	ligase activity
K09K1_23000	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
K09K1_23010	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
K09K1_23020	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
K09K1_23030	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
K09K1_23040	COG1434	Gram-negative-bacterium-type cell wall biogenesis
K09K1_23050	COG0745	RESPONSE REGULATOR receiver
K09K1_23060	COG3381	protein complex oligomerization
K09K1_23070	COG1609	Transcriptional regulator
K09K1_23080	COG3070	regulator of competence-specific genes
K09K1_23120	COG0297	glycogen (starch) synthase activity
K09K1_23130	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
K09K1_23140	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
K09K1_23180	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
K09K1_23190	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
K09K1_23200	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
K09K1_23210	COG0542	response to heat
K09K1_23220	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
K09K1_23230	COG1278	Cold shock
K09K1_23250	COG1187	pseudouridine synthase activity
K09K1_23260	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
K09K1_23270	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
K09K1_23290	COG1199	ATP-dependent helicase activity
K09K1_23300	COG0730	response to heat
K09K1_23310	COG3923	Primosomal replication protein n
K09K1_23330	COG0708	Exodeoxyribonuclease III
K09K1_23360	COG4215	(ABC) transporter
K09K1_23410	COG1882	Formate acetyltransferase
K09K1_23430	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
K09K1_23450	COG3013	Belongs to the UPF0304 family
K09K1_23460	COG2766	serine protein kinase
K09K1_23470	COG2718	Belongs to the UPF0229 family
K09K1_23480	COG2719	SpoVR family
K09K1_23520	COG1132	(ABC) transporter
K09K1_23530	COG2333	competence protein COMEC
K09K1_23530	COG0658	competence protein
K09K1_23550	COG4591	ABC-type transport system involved in lipoprotein release permease component
K09K1_23560	COG1136	(ABC) transporter
K09K1_23570	COG4591	ABC-type transport system involved in lipoprotein release permease component
K09K1_23590	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
K09K1_23620	COG1252	NADH dehydrogenase
K09K1_23630	COG3150	esterase
K09K1_23680	COG0537	adenosine 5'-monophosphoramidase activity
K09K1_23730	COG0516	GMP reductase activity
K09K1_23730	COG0517	IMP dehydrogenase activity
K09K1_23740	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
K09K1_23750	COG3706	GGDEF domain
K09K1_23780	COG3126	Type III secretion system lipoprotein chaperone (YscW)
K09K1_23790	COG1946	Acyl-CoA thioesterase
K09K1_23810	COG1522	sequence-specific DNA binding
K09K1_23820	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
K09K1_23850	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
K09K1_23860	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
K09K1_23950	COG0477	Major facilitator Superfamily
K09K1_23960	COG2855	membrane
K09K1_23990	COG1441	menaquinone biosynthetic process
K09K1_24000	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
K09K1_24020	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
K09K1_24030	COG1169	isochorismate synthase
K09K1_24040	COG0436	Aminotransferase
K09K1_24050	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
K09K1_24060	COG0232	Belongs to the dGTPase family. Type 2 subfamily
K09K1_24090	COG1555	photosystem II stabilization
K09K1_24100	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
K09K1_24110	COG0776	regulation of translation
K09K1_24120	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
K09K1_24130	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
K09K1_24150	COG0544	peptidyl-prolyl cis-trans isomerase activity
K09K1_24190	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
K09K1_24200	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
K09K1_24210	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
K09K1_24220	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
K09K1_24260	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
K09K1_24270	COG0569	domain protein
K09K1_24280	COG0513	Belongs to the DEAD box helicase family
K09K1_24350	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
K09K1_24360	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
K09K1_24390	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
K09K1_24400	COG1216	Glycosyl transferase, family 2
K09K1_24410	COG2986	histidine ammonia-lyase
K09K1_24460	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
K09K1_24470	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
K09K1_24480	COG1028	Short-chain dehydrogenase reductase Sdr
K09K1_24500	COG2226	methyltransferase
K09K1_24520	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
K09K1_24530	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
K09K1_24550	COG2951	lytic endotransglycosylase activity
K09K1_24560	COG3100	YcgL domain-containing protein
K09K1_24570	COG0850	regulation of cytokinetic process
K09K1_24580	COG2894	cell division
K09K1_24600	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
K09K1_24610	COG0318	PFAM AMP-dependent synthetase and ligase
K09K1_24620	COG2267	carboxylic ester hydrolase activity
K09K1_24630	COG3065	identical protein binding
K09K1_24650	COG1214	PFAM Peptidase M22, glycoprotease
K09K1_24660	COG1199	ATP-dependent helicase activity
K09K1_24670	COG0788	formyltetrahydrofolate deformylase activity
K09K1_24700	COG3102	Protein conserved in bacteria
K09K1_24710	COG0018	arginyl-trna synthetase
K09K1_24760	COG1918	ferrous iron import across plasma membrane
K09K1_24770	COG4977	sequence-specific DNA binding
K09K1_24780	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
K09K1_24790	COG1121	(ABC) transporter
K09K1_24800	COG1108	ABC-type Mn2 Zn2 transport systems permease components
K09K1_24820	COG0045	succinate-CoA ligase (ADP-forming) activity
K09K1_24830	COG0508	dehydrogenase complex catalyzes the overall conversion of
K09K1_24840	COG0567	Dehydrogenase, E1 component
K09K1_24850	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
K09K1_24860	COG1053	succinate dehydrogenase
K09K1_24870	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
K09K1_24880	COG2009	succinate dehydrogenase
K09K1_24900	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
K09K1_24920	COG0033	Phosphoglucomutase
K09K1_24930	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
K09K1_24940	COG0596	Alpha beta hydrolase
K09K1_24960	COG0716	FMN binding
K09K1_24980	COG0735	belongs to the Fur family
K09K1_24990	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
K09K1_25000	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
K09K1_25000	COG1263	PTS System
K09K1_25000	COG2190	(PTS) system
K09K1_25010	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
K09K1_25020	COG1940	carbohydrate kinase activity
K09K1_25020	COG1846	Transcriptional regulator
K09K1_25030	COG4651	solute:proton antiporter activity
K09K1_25030	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
K09K1_25040	COG0367	asparagine synthase
K09K1_25050	COG0250	Participates in transcription elongation, termination and antitermination
K09K1_25060	COG3104	oligopeptide transport
K09K1_25070	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
K09K1_25090	COG0326	Molecular chaperone. Has ATPase activity
K09K1_25100	COG3710	Transcriptional regulator
K09K1_25140	COG0622	Phosphoesterase
K09K1_25200	COG1090	epimerase
K09K1_25210	COG0300	oxidoreductase activity
K09K1_25220	COG3118	belongs to the thioredoxin family
K09K1_25230	COG3118	belongs to the thioredoxin family
K09K1_25230	COG0457	Tetratricopeptide repeat
K09K1_25240	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
K09K1_25260	COG1215	transferase activity, transferring glycosyl groups
K09K1_25270	COG1192	Involved in chromosome partitioning
K09K1_25310	COG2194	sulfuric ester hydrolase activity
K09K1_25320	COG0330	HflC and HflK could
K09K1_25370	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
K09K1_25380	COG3115	cell septum assembly
K09K1_25390	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
K09K1_25400	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
K09K1_25410	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
K09K1_25430	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
K09K1_25440	COG2190	(PTS) system
K09K1_25450	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
K09K1_25460	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
K09K1_25470	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
K09K1_25480	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
K09K1_25500	COG3951	Flagellar rod assembly protein muramidase FlgJ
K09K1_25500	COG1705	Flagellar rod assembly protein muramidase FlgJ
K09K1_25510	COG1706	bacterial-type flagellum-dependent cell motility
K09K1_25520	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
K09K1_25530	COG4786	Flagellar basal body rod
K09K1_25540	COG4787	bacterial-type flagellum-dependent cell motility
K09K1_25550	COG1749	Flagellar hook protein flgE
K09K1_25560	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
K09K1_25570	COG1558	bacterial-type flagellum-dependent cell motility
K09K1_25580	COG1815	bacterial-type flagellum-dependent cell motility
K09K1_25590	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
K09K1_25600	COG0835	chemotaxis
K09K1_25600	COG0784	Response regulator, receiver
K09K1_25710	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
K09K1_25730	COG2217	Heavy metal translocating P-type atpase
K09K1_25730	COG2608	mercury ion transmembrane transporter activity
K09K1_25810	COG2840	Smr protein MutS2
K09K1_25820	COG1187	pseudouridine synthase activity
K09K1_25830	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
K09K1_25840	COG0737	Belongs to the 5'-nucleotidase family
K09K1_25850	COG2877	3-deoxy-8-phosphooctulonate synthase activity
K09K1_25860	COG2912	Transglutaminase-like superfamily
K09K1_25870	COG3094	Invasion gene expression up-regulator, SirB
K09K1_25880	COG2890	protein-(glutamine-N5) methyltransferase activity
K09K1_25900	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
K09K1_25910	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
K09K1_25920	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
K09K1_25930	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
K09K1_25940	COG0193	aminoacyl-tRNA hydrolase activity
K09K1_25950	COG0012	GTP binding
K09K1_26160	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
K09K1_26170	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
K09K1_26180	COG1702	phosphate starvation-inducible protein PhoH
K09K1_26190	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
K09K1_26200	COG4535	Mg2 and Co2 transporter CorC
K09K1_26210	COG0815	Transfers the fatty acyl group on membrane lipoproteins
K09K1_26220	COG2888	peptidyl-tyrosine sulfation
K09K1_26230	COG0495	leucyl-tRNA aminoacylation
K09K1_26240	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
K09K1_26250	COG1466	dna polymerase III delta subunit
K09K1_26260	COG0799	negative regulation of ribosome biogenesis
K09K1_26270	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
K09K1_26280	COG0768	penicillin binding
K09K1_26290	COG0772	Belongs to the SEDS family
K09K1_26300	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
K09K1_26310	COG1686	Belongs to the peptidase S11 family
K09K1_26330	COG0321	lipoyl(octanoyl) transferase activity
K09K1_26340	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
K09K1_26350	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
K09K1_26360	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
K09K1_26390	COG0366	Alpha amylase catalytic
K09K1_26400	COG1263	PTS System
K09K1_26400	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
K09K1_26420	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
K09K1_26430	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
K09K1_26440	COG2011	ABC-type metal ion transport system permease component
K09K1_26450	COG1464	Belongs to the NlpA lipoprotein family
K09K1_26460	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
K09K1_26480	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
K09K1_26480	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
K09K1_26500	COG0745	RESPONSE REGULATOR receiver
K09K1_26500	COG3706	GGDEF domain
K09K1_26510	COG1611	Belongs to the LOG family
K09K1_26520	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
K09K1_26540	COG2363	Small membrane protein
K09K1_26560	COG0583	DNA-binding transcription factor activity
K09K1_26570	COG0301	tRNA thio-modification
K09K1_26570	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
K09K1_26590	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
K09K1_26600	COG1722	exodeoxyribonuclease VII activity
K09K1_26610	COG0142	geranyltranstransferase activity
K09K1_26620	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
K09K1_26630	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
K09K1_26640	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
K09K1_26690	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
K09K1_26690	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
K09K1_26700	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
K09K1_26710	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
K09K1_26720	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
K09K1_26750	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
K09K1_26760	COG2252	PERMEase
K09K1_26770	COG2195	Cleaves the N-terminal amino acid of tripeptides
K09K1_26830	COG0047	phosphoribosylformylglycinamidine synthase activity
K09K1_26830	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
K09K1_26840	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
K09K1_26850	COG0590	tRNA wobble adenosine to inosine editing
K09K1_26860	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
K09K1_26920	COG0484	heat shock protein binding
K09K1_26940	COG1301	dicarboxylic acid transport
K09K1_26960	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
K09K1_26970	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
K09K1_26990	COG0497	DNA recombination
K09K1_27010	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
K09K1_27020	COG2914	Belongs to the UPF0125 (RnfH) family
K09K1_27030	COG2867	negative regulation of translational initiation
K09K1_27040	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
K09K1_27080	COG0583	DNA-binding transcription factor activity
K09K1_27090	COG3153	acetyltransferase
K09K1_27090	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
K09K1_27130	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
K09K1_27140	COG2873	o-acetylhomoserine
K09K1_27170	COG1115	amino acid carrier protein
K09K1_27180	COG1584	GPR1 FUN34 yaaH family protein
K09K1_27200	COG1757	Na H antiporter
K09K1_27340	COG0582	viral genome integration into host DNA
K09K1_27360	COG0517	IMP dehydrogenase activity
K09K1_27360	COG0516	GMP reductase activity
K09K1_27400	COG1160	GTP binding
K09K1_27410	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
K09K1_27420	COG2976	Protein conserved in bacteria
K09K1_27430	COG0124	histidyl-tRNA synthetase
K09K1_27440	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
K09K1_27470	COG0105	UTP biosynthetic process
K09K1_27490	COG2975	iron-sulfur cluster assembly
K09K1_27500	COG0633	Ferredoxin
K09K1_27510	COG0443	Heat shock 70 kDa protein
K09K1_27540	COG0822	iron-sulfur transferase activity
K09K1_27550	COG1104	cysteine desulfurase activity
K09K1_27570	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
K09K1_27580	COG0483	inositol monophosphate 1-phosphatase activity
K09K1_27610	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
K09K1_27620	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
K09K1_27630	COG1862	Preprotein translocase
K09K1_27650	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
K09K1_27670	COG0517	IMP dehydrogenase activity
K09K1_27690	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
K09K1_27700	COG0583	DNA-binding transcription factor activity
K09K1_27710	COG0450	alkyl hydroperoxide reductase
K09K1_27720	COG3142	Participates in the control of copper homeostasis
K09K1_27740	COG0704	Plays a role in the regulation of phosphate uptake
K09K1_27750	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
K09K1_27760	COG0581	inorganic phosphate transmembrane transporter activity
K09K1_27770	COG0573	inorganic phosphate transmembrane transporter activity
K09K1_27780	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
K09K1_27790	COG0248	Ppx GppA phosphatase
K09K1_27810	COG5002	protein histidine kinase activity
K09K1_27820	COG0745	RESPONSE REGULATOR receiver
K09K1_27830	COG2974	May be involved in recombination
K09K1_27850	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
K09K1_27970	COG0542	response to heat
K09K1_27990	COG0564	pseudouridine synthase activity
K09K1_28000	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
K09K1_28020	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
K09K1_28030	COG0077	Prephenate dehydratase
K09K1_28030	COG1605	Chorismate mutase
K09K1_28040	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
K09K1_28050	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
K09K1_28070	COG0488	(ABC) transporter
K09K1_28090	COG0739	heme binding
K09K1_28100	COG1605	Chorismate mutase
K09K1_28100	COG0287	Prephenate dehydrogenase
K09K1_28110	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
K09K1_28120	COG1472	Belongs to the glycosyl hydrolase 3 family
K09K1_28130	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
K09K1_28170	COG1966	Carbon starvation protein
K09K1_28180	COG3275	phosphorelay sensor kinase activity
K09K1_28190	COG3279	Response regulator of the LytR AlgR family
K09K1_28210	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
K09K1_28220	COG1047	Peptidyl-prolyl cis-trans
K09K1_28250	COG0196	riboflavin kinase activity
K09K1_28260	COG0728	peptidoglycan biosynthetic process
K09K1_28270	COG0268	Binds directly to 16S ribosomal RNA
K09K1_28280	COG0640	Transcriptional regulator
K09K1_28290	COG0583	DNA-binding transcription factor activity
K09K1_28300	COG1283	sodium-dependent phosphate transmembrane transporter activity
K09K1_28320	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
K09K1_28340	COG0730	response to heat
K09K1_28390	COG0667	Aldo Keto reductase
K09K1_28420	COG2204	response regulator
K09K1_28440	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
K09K1_28450	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
K09K1_28460	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
K09K1_28480	COG0716	FMN binding
K09K1_28500	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
K09K1_28510	COG0513	Belongs to the DEAD box helicase family
K09K1_28520	COG3022	response to hydroperoxide
K09K1_28530	COG1115	amino acid carrier protein
K09K1_28560	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
K09K1_28570	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
K09K1_28580	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
K09K1_28600	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
K09K1_28610	COG0083	homoserine kinase activity
K09K1_28640	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
K09K1_28660	COG0745	RESPONSE REGULATOR receiver
K09K1_28680	COG5002	protein histidine kinase activity
K09K1_28680	COG2198	Histidine kinase
K09K1_28680	COG0784	Response regulator, receiver
K09K1_28690	COG2203	Gaf domain
K09K1_28690	COG3706	GGDEF domain
K09K1_28690	COG4251	negative regulation of phosphorylation
K09K1_28690	COG5001	Diguanylate cyclase
K09K1_28700	COG1242	4 iron, 4 sulfur cluster binding
K09K1_28710	COG0067	glutamate synthase
K09K1_28710	COG0069	glutamate synthase activity
K09K1_28710	COG0070	glutamate synthase
K09K1_28730	COG0070	glutamate synthase
K09K1_28730	COG0069	glutamate synthase activity
K09K1_28730	COG0067	glutamate synthase
K09K1_28740	COG0493	'glutamate synthase
K09K1_28760	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
K09K1_28790	COG2860	membrane
K09K1_28800	COG0583	DNA-binding transcription factor activity
K09K1_28810	COG0730	response to heat
K09K1_28840	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
K09K1_28850	COG0505	Belongs to the CarA family
K09K1_28870	COG0494	nUDIX hydrolase
K09K1_28880	COG0653	protein targeting
K09K1_28900	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
K09K1_28910	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
K09K1_28920	COG0849	cell division
K09K1_28930	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
K09K1_28960	COG0772	Belongs to the SEDS family
K09K1_28970	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
K09K1_28980	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
K09K1_28990	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
K09K1_29000	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
K09K1_29010	COG0768	penicillin binding
K09K1_29020	COG3116	cell division
K09K1_29040	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
K09K1_29070	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
K09K1_29080	COG2823	Periplasmic or secreted lipoprotein
K09K1_29110	COG2969	positive regulation of protein catabolic process
K09K1_29120	COG0625	glutathione transferase activity
K09K1_29130	COG2857	Cytochrome c1
K09K1_29140	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
K09K1_29150	COG0723	plastoquinol--plastocyanin reductase activity
K09K1_29160	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
K09K1_29180	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
K09K1_29190	COG3105	Protein conserved in bacteria
K09K1_29210	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
K09K1_29220	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
K09K1_29230	COG0187	DNA topoisomerase II activity
K09K1_29240	COG3150	esterase
K09K1_29260	COG3151	Protein conserved in bacteria
K09K1_29270	COG0494	nUDIX hydrolase
K09K1_29280	COG1538	Outer membrane efflux protein
K09K1_29290	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
K09K1_29290	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
K09K1_29300	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
K09K1_29330	COG3025	triphosphatase activity
K09K1_29340	COG1392	Phosphate transport regulator
K09K1_29350	COG0306	phosphate transporter
K09K1_29360	COG4991	sh3 domain protein
K09K1_29370	COG0405	Gamma-glutamyltransferase
K09K1_29390	COG3409	Peptidoglycan-binding domain 1 protein
K09K1_29390	COG3267	Type II secretory pathway component ExeA
K09K1_29410	COG1968	undecaprenyl-diphosphatase activity
K09K1_29420	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
K09K1_29430	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
K09K1_29440	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
K09K1_29450	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
K09K1_29460	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
K09K1_29470	COG0828	Belongs to the bacterial ribosomal protein bS21 family
K09K1_29480	COG1610	YqeY-like protein
K09K1_29490	COG0358	DNA primase activity
K09K1_29500	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
K09K1_29560	COG2213	PTS system mannitol-specific
K09K1_29560	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
K09K1_29580	COG3722	fumarate hydratase activity
K09K1_29610	COG1461	Dihydroxyacetone kinase
K09K1_29620	COG2376	Dihydroxyacetone kinase
K09K1_29640	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
K09K1_29650	COG1349	DNA-binding transcription factor activity
K09K1_29660	COG0469	pyruvate kinase activity
K09K1_29680	COG3706	GGDEF domain
K09K1_29690	COG0440	acetolactate synthase activity
K09K1_29700	COG0028	Belongs to the TPP enzyme family
K09K1_29710	COG1022	Amp-dependent synthetase and ligase
K09K1_29720	COG0583	DNA-binding transcription factor activity
K09K1_29760	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
K09K1_29770	COG0473	3-isopropylmalate dehydrogenase activity
K09K1_29810	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
K09K1_29820	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
K09K1_29830	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
K09K1_29840	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
K09K1_29850	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
K09K1_29860	COG2967	ApaG domain
K09K1_29870	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
K09K1_29880	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
K09K1_29900	COG2966	Psort location CytoplasmicMembrane, score
K09K1_29910	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
K09K1_29930	COG0261	This protein binds to 23S rRNA in the presence of protein L20
K09K1_29940	COG0142	geranyltranstransferase activity
K09K1_30010	COG1902	pentaerythritol trinitrate reductase activity
K09K1_30020	COG0583	DNA-binding transcription factor activity
K09K1_30030	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
K09K1_30040	COG1178	ABC-type Fe3 transport system permease component
K09K1_30050	COG4143	(ABC) transporter
K09K1_30060	COG0163	prenyltransferase activity
K09K1_30070	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
K09K1_30080	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
K09K1_30090	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
K09K1_30110	COG2105	PFAM AIG2 family protein
K09K1_30120	COG2911	Protein conserved in bacteria
K09K1_30130	COG0729	surface antigen
K09K1_30140	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
K09K1_30160	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
K09K1_30190	COG4181	ATPase activity
K09K1_30240	COG0529	Catalyzes the synthesis of activated sulfate
K09K1_30250	COG0471	metal ion transport
K09K1_30250	COG3273	potassium ion transport
K09K1_30260	COG2895	sulfate adenylyltransferase (ATP) activity
K09K1_30270	COG0175	sulfate reduction
K09K1_30280	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
K09K1_30280	COG1648	precorrin-2 dehydrogenase activity
K09K1_30310	COG0513	Belongs to the DEAD box helicase family
K09K1_30320	COG2153	protein acetylation
K09K1_30340	COG0545	Peptidyl-prolyl cis-trans isomerase
K09K1_30360	COG0203	ribosomal protein L17
K09K1_30370	COG0202	RNA polymerase activity
K09K1_30390	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
K09K1_30400	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
K09K1_30420	COG0201	protein transport
K09K1_30440	COG1841	ribosomal large subunit assembly
K09K1_30470	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
K09K1_30480	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
K09K1_30490	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
K09K1_30500	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
K09K1_30510	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
K09K1_30530	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
K09K1_30540	COG0255	Belongs to the universal ribosomal protein uL29 family
K09K1_30560	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
K09K1_30570	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
K09K1_30580	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
K09K1_30590	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
K09K1_30610	COG0088	Forms part of the polypeptide exit tunnel
K09K1_30620	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
K09K1_30640	COG0254	rRNA binding
K09K1_30650	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
K09K1_30660	COG1609	Transcriptional regulator
K09K1_30690	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
K09K1_30700	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
K09K1_30730	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
K09K1_30740	COG3697	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
K09K1_30750	COG3051	citrate lyase alpha subunit
K09K1_30760	COG2301	Belongs to the HpcH HpaI aldolase family
K09K1_30770	COG3052	prosthetic group binding
K09K1_30780	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
K09K1_30800	COG3630	sodium ion export across plasma membrane
K09K1_30810	COG5016	pyruvate
K09K1_30810	COG0511	ligase activity, forming carbon-carbon bonds
K09K1_30820	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
K09K1_30840	COG4565	transcriptional regulatory protein
K09K1_30870	COG2003	Belongs to the UPF0758 family
K09K1_30930	COG1575	Belongs to the MenA family. Type 1 subfamily
K09K1_30940	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
K09K1_30960	COG1494	fructose-1,6-bisphosphatase
K09K1_31010	COG0149	triose-phosphate isomerase activity
K09K1_31060	COG1215	transferase activity, transferring glycosyl groups
K09K1_31130	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
K09K1_31140	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
K09K1_31150	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
K09K1_31170	COG0438	transferase activity, transferring glycosyl groups
K09K1_31170	COG0297	glycogen (starch) synthase activity
K09K1_31190	COG0438	transferase activity, transferring glycosyl groups
K09K1_31300	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
K09K1_31370	COG0859	PFAM glycosyl transferase family 9
K09K1_31380	COG1519	Transferase
K09K1_31390	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
K09K1_31470	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
K09K1_31490	COG3642	lipopolysaccharide core region biosynthetic process
K09K1_31500	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
K09K1_31510	COG0859	PFAM glycosyl transferase family 9
K09K1_31520	COG0463	Glycosyl transferase, family 2
K09K1_31550	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
K09K1_31600	COG2003	Belongs to the UPF0758 family
K09K1_31620	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
K09K1_31630	COG1309	transcriptional regulator
K09K1_31640	COG1560	Kdo2-lipid A biosynthetic process
K09K1_31650	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
K09K1_31660	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
K09K1_31670	COG1561	YicC-like family, N-terminal region
K09K1_31690	COG4608	Belongs to the ABC transporter superfamily
K09K1_31700	COG0444	Belongs to the ABC transporter superfamily
K09K1_31710	COG0747	negative chemotaxis
K09K1_31720	COG4239	(ABC) transporter, permease
K09K1_31730	COG4174	ABC transporter (Permease)
K09K1_31770	COG0811	peptide transport
K09K1_31780	COG0848	biopolymer transport protein
K09K1_31810	COG0194	GDP metabolic process
K09K1_31820	COG1758	RNA polymerase activity
K09K1_31830	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
K09K1_31840	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
K09K1_31850	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
K09K1_31860	COG2233	PERMEase
K09K1_31870	COG2205	protein histidine kinase activity
K09K1_31880	COG0745	RESPONSE REGULATOR receiver
K09K1_31900	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
K09K1_31920	COG2183	response to ionizing radiation
K09K1_31950	COG1040	competence protein
K09K1_31970	COG0494	nUDIX hydrolase
K09K1_31980	COG1218	3'(2'),5'-bisphosphate nucleotidase
K09K1_32000	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
K09K1_32010	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
K09K1_32020	COG3156	type II secretion system protein K
K09K1_32030	COG4795	General secretion pathway protein
K09K1_32040	COG2165	general secretion pathway protein
K09K1_32050	COG2165	general secretion pathway protein
K09K1_32060	COG2165	general secretion pathway protein
K09K1_32070	COG1459	type II secretion system
K09K1_32080	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
K09K1_32100	COG3031	protein transport across the cell outer membrane
K09K1_32110	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
K09K1_32120	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
K09K1_32130	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
K09K1_32150	COG0456	acetyltransferase
K09K1_32160	COG1490	D-aminoacyl-tRNA deacylase activity
K09K1_32170	COG1295	ribonuclease BN
K09K1_32190	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
K09K1_32210	COG0174	glutamine synthetase
K09K1_32230	COG3852	Histidine kinase
K09K1_32240	COG2204	response regulator
K09K1_32260	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
K09K1_32270	COG0635	Involved in the biosynthesis of porphyrin-containing compound
K09K1_32320	COG0218	Necessary for normal cell division and for the maintenance of normal septation
K09K1_32330	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
K09K1_32330	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
K09K1_32350	COG0456	acetyltransferase
K09K1_32370	COG0084	hydrolase, TatD family'
K09K1_32380	COG0805	protein transport
K09K1_32410	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
K09K1_32420	COG3165	ubiquinone biosynthetic process from chorismate
K09K1_32430	COG2226	methyltransferase
K09K1_32440	COG1322	Protein conserved in bacteria
K09K1_32470	COG0628	permease
K09K1_32530	COG1597	lipid kinase activity
K09K1_32590	COG2081	HI0933 family
K09K1_32610	COG1528	Iron-storage protein
K09K1_32620	COG0589	response to stress
K09K1_32630	COG0697	spore germination
K09K1_32650	COG0742	ribosomal rna small subunit methyltransferase
K09K1_32660	COG5002	protein histidine kinase activity
K09K1_32660	COG5001	Diguanylate cyclase
K09K1_32670	COG1522	sequence-specific DNA binding
K09K1_32690	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
K09K1_32700	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
K09K1_32710	COG0583	DNA-binding transcription factor activity
K09K1_32720	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
K09K1_32730	COG0800	Aldolase
K09K1_32740	COG2610	gluconate transmembrane transporter activity
K09K1_32750	COG3265	gluconokinase activity
K09K1_32760	COG0129	dihydroxy-acid dehydratase activity
K09K1_32770	COG2076	Multidrug Resistance protein
K09K1_32790	COG0583	DNA-binding transcription factor activity
K09K1_32800	COG1609	Transcriptional regulator
K09K1_32820	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
K09K1_32840	COG4166	transmembrane transport
K09K1_32850	COG4172	Belongs to the ABC transporter superfamily
K09K1_32950	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
K09K1_32960	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
K09K1_32970	COG2960	long-chain fatty acid transporting porin activity
K09K1_32980	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
K09K1_32990	COG0583	DNA-binding transcription factor activity
K09K1_33070	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
K09K1_33080	COG1739	Uncharacterized protein family UPF0029
K09K1_33100	COG0183	Belongs to the thiolase family
K09K1_33110	COG0604	alcohol dehydrogenase
K09K1_33140	COG0425	Belongs to the sulfur carrier protein TusA family
K09K1_33160	COG2119	membrane
K09K1_33190	COG0366	Alpha amylase catalytic
K09K1_33200	COG3977	Valine--pyruvate aminotransferase
K09K1_33210	COG0071	Belongs to the small heat shock protein (HSP20) family
K09K1_33240	COG0187	DNA topoisomerase II activity
K09K1_33260	COG0592	DNA-directed DNA polymerase activity
K09K1_33270	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
K09K1_33300	COG1126	abc transporter atp-binding protein
K09K1_33320	COG0594	ribonuclease P activity
K09K1_33330	COG0706	membrane insertase activity
K09K1_33350	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
K09K1_33360	COG0445	tRNA wobble uridine modification
K09K1_33370	COG0357	Ribosomal RNA small subunit methyltransferase G
K09K1_33380	COG1192	Involved in chromosome partitioning
K09K1_33390	COG1475	DNA binding
K09K1_33400	COG3312	ion transport
K09K1_33410	COG0356	it plays a direct role in the translocation of protons across the membrane
K09K1_33430	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
K09K1_33440	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
K09K1_33450	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
K09K1_33460	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
K09K1_33470	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
K09K1_33480	COG0355	proton-transporting ATP synthase activity, rotational mechanism
K09K1_33510	COG0765	amino acid transport
K09K1_33530	COG2814	Major facilitator Superfamily
K09K1_33540	COG0583	DNA-binding transcription factor activity
K09K1_33560	COG0129	dihydroxy-acid dehydratase activity
K09K1_33570	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
K09K1_33580	COG3978	acetolactate synthase activity
K09K1_33630	COG0204	Acyl-transferase
K09K1_33640	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
K09K1_33650	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
K09K1_33670	COG3084	Protein conserved in bacteria
K09K1_33690	COG4326	sporulation control protein
K09K1_33700	COG1272	protein, Hemolysin III
K09K1_33720	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
K09K1_33730	COG0569	domain protein
K09K1_33740	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
K09K1_33740	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
K09K1_33750	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
K09K1_33760	COG0242	peptide deformylase activity
K09K1_33780	COG0758	DNA mediated transformation
K09K1_33790	COG2922	Belongs to the Smg family
K09K1_33800	COG0551	DNA topoisomerase type I activity
K09K1_33810	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
K09K1_33820	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
K09K1_33830	COG0009	L-threonylcarbamoyladenylate synthase
K09K1_33870	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
K09K1_33970	COG2132	Multicopper oxidase
K09K1_34010	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
K09K1_34020	COG2104	thiamine diphosphate biosynthetic process
K09K1_34050	COG0006	proline dipeptidase activity
K09K1_34050	COG0006	proline dipeptidase activity
K09K1_34110	COG3220	belongs to the UPF0276 family
K09K1_34130	COG0210	DNA helicase
K09K1_34140	COG0405	Gamma-glutamyltransferase
K09K1_34150	COG1280	lysine exporter protein (LysE YggA)
K09K1_34170	COG2962	Rard protein
K09K1_34180	COG0514	ATP-dependent DNA helicase (RecQ)
K09K1_34200	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
K09K1_34220	COG0248	Ppx GppA phosphatase
K09K1_34230	COG0513	Belongs to the DEAD box helicase family
K09K1_34240	COG3118	belongs to the thioredoxin family
K09K1_34250	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
K09K1_34270	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
K09K1_34280	COG0633	Ferredoxin
K09K1_34390	COG2959	enzyme of heme biosynthesis
K09K1_34400	COG1587	Uroporphyrinogen-III synthase
K09K1_34410	COG0181	hydroxymethylbilane synthase activity
K09K1_34420	COG3072	Adenylate cyclase
K09K1_34430	COG1965	Belongs to the frataxin family
K09K1_34440	COG0019	diaminopimelate decarboxylase activity
K09K1_34470	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
K09K1_34480	COG1011	Hydrolase
K09K1_34490	COG2199	diguanylate cyclase activity
K09K1_34490	COG3287	FIST C domain
K09K1_34490	COG2200	EAL domain
K09K1_34530	COG0561	phosphatase activity
K09K1_34540	COG2267	carboxylic ester hydrolase activity
K09K1_34550	COG1280	lysine exporter protein (LysE YggA)
K09K1_34560	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
K09K1_34570	COG0640	Transcriptional regulator
K09K1_34580	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
K09K1_34660	COG2095	MarC family integral membrane protein
K09K1_34680	COG0742	ribosomal rna small subunit methyltransferase
K09K1_34690	COG0552	protein localization to endoplasmic reticulum
K09K1_34700	COG2884	Cell division ATP-binding protein ftsE
K09K1_34710	COG2177	Part of the ABC transporter FtsEX involved in
K09K1_34730	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
K09K1_34740	COG0705	Rhomboid family
K09K1_34750	COG1580	Controls the rotational direction of flagella during chemotaxis
K09K1_34760	COG3161	chorismate lyase activity
K09K1_34770	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
K09K1_34780	COG2937	Belongs to the GPAT DAPAT family
K09K1_34790	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
K09K1_34800	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
K09K1_34810	COG0534	Mate efflux family protein
K09K1_34820	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
K09K1_34860	COG4206	TonB-dependent receptor
K09K1_35020	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
K09K1_35040	COG0812	UDP-N-acetylmuramate dehydrogenase activity
K09K1_35050	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
K09K1_35050	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
K09K1_35110	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
K09K1_35120	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
K09K1_35130	COG0250	Participates in transcription elongation, termination and antitermination
K09K1_35160	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
K09K1_35170	COG0222	ribosome binding
K09K1_35180	COG0085	RNA polymerase activity
K09K1_35190	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
K09K1_35200	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
K09K1_35210	COG2816	NAD+ diphosphatase activity
K09K1_35220	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
K09K1_35230	COG1573	uracil-dna glycosylase
K09K1_35250	COG3068	Protein conserved in bacteria
K09K1_35260	COG1253	flavin adenine dinucleotide binding
K09K1_35290	COG0151	Belongs to the GarS family
K09K1_35310	COG0789	Transcriptional regulator
K09K1_35320	COG3710	Transcriptional regulator
K09K1_35330	COG0531	amino acid
K09K1_35340	COG1982	Orn Lys Arg decarboxylase major
K09K1_35440	COG0488	(ABC) transporter
K09K1_35460	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
K09K1_35470	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
K09K1_35480	COG2264	protein methyltransferase activity
K09K1_35490	COG0439	Biotin carboxylase
K09K1_35500	COG0511	ligase activity, forming carbon-carbon bonds
K09K1_35510	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
K09K1_35520	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
K09K1_35550	COG2814	Major facilitator Superfamily
K09K1_35600	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
K09K1_35620	COG3263	regulation of cellular component size
K09K1_35640	COG4232	protein-disulfide reductase activity
K09K1_35650	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
K09K1_35660	COG1027	Aspartate ammonia-lyase
K09K1_35670	COG3030	protein affecting phage T7 exclusion by the F plasmid
K09K1_35680	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
K09K1_35700	COG2205	protein histidine kinase activity
K09K1_35710	COG0745	RESPONSE REGULATOR receiver
K09K1_35720	COG3678	ATP-independent chaperone mediated protein folding
K09K1_35730	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
K09K1_35740	COG0205	6-phosphofructokinase activity
K09K1_35750	COG0534	Mate efflux family protein
K09K1_35760	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
K09K1_35770	COG0459	protein refolding
K09K1_35790	COG1285	pathogenesis
K09K1_35800	COG1509	lysine 2,3-aminomutase activity
K09K1_35830	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
K09K1_35840	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
K09K1_35850	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
K09K1_35860	COG1053	succinate dehydrogenase
K09K1_35870	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
K09K1_35910	COG4942	peptidase
K09K1_35920	COG1045	serine acetyltransferase
K09K1_35930	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
K09K1_35940	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
K09K1_35950	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
K09K1_35960	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
K09K1_35980	COG0471	metal ion transport
K09K1_35990	COG0688	phosphatidylethanolamine metabolic process
K09K1_36000	COG1162	GTPase activity
K09K1_36010	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
K09K1_36140	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
K09K1_36160	COG0802	atpase or kinase
K09K1_36180	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
K09K1_36190	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
K09K1_36210	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
K09K1_36220	COG0330	HflC and HflK could
K09K1_36230	COG0330	HflC and HflK could
K09K1_36240	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
K09K1_36250	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
K09K1_36260	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
K09K1_36270	COG1017	nitric oxide dioxygenase activity
K09K1_36270	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
K09K1_36280	COG1959	2 iron, 2 sulfur cluster binding
K09K1_36290	COG0557	exoribonuclease II activity
K09K1_36300	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
K09K1_36310	COG0546	phosphoglycolate phosphatase activity
K09K1_36320	COG0180	Tryptophanyl-tRNA synthetase
K09K1_36350	COG0512	Glutamine amidotransferase of anthranilate synthase
K09K1_36360	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
K09K1_36400	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
K09K1_36410	COG3954	Phosphoribulokinase
K09K1_36430	COG0429	hydrolase of the alpha beta-hydrolase fold
K09K1_36450	COG0488	(ABC) transporter
K09K1_36460	COG2249	NAD(P)H dehydrogenase (quinone) activity
K09K1_36490	COG1047	Peptidyl-prolyl cis-trans
K09K1_36500	COG1446	asparaginase
K09K1_36530	COG0545	Peptidyl-prolyl cis-trans isomerase
K09K1_36540	COG2964	Protein conserved in bacteria
K09K1_36550	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
K09K1_36560	COG2923	Belongs to the DsrF TusC family
K09K1_36600	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
K09K1_36610	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
K09K1_36620	COG2906	2 iron, 2 sulfur cluster binding
K09K1_36640	COG0281	malic enzyme
K09K1_36660	COG0626	cystathionine gamma-synthase activity
K09K1_36670	COG0527	aspartate kinase activity
K09K1_36670	COG0460	homoserine dehydrogenase
K09K1_36680	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
K09K1_36700	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
K09K1_36720	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
K09K1_36740	COG0137	argininosuccinate synthase activity
K09K1_36750	COG0165	Argininosuccinate lyase
K09K1_36750	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
K09K1_36780	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
K09K1_36790	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
K09K1_36790	COG0678	peroxiredoxin activity
K09K1_36810	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
K09K1_36870	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
K09K1_36880	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
K09K1_36900	COG0338	D12 class N6 adenine-specific DNA methyltransferase
K09K1_36910	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
K09K1_36920	COG0360	Binds together with S18 to 16S ribosomal RNA
K09K1_36930	COG2965	DNA replication, synthesis of RNA primer
K09K1_36970	COG0305	Participates in initiation and elongation during chromosome replication
K09K1_36980	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
K09K1_36990	COG0432	Pfam Uncharacterised protein family UPF0047
K09K1_37000	COG0166	Belongs to the GPI family
K09K1_37020	COG0735	belongs to the Fur family
K09K1_37030	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
K09K1_37070	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
K09K1_37080	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
K09K1_37090	COG0175	sulfate reduction
K09K1_37210	COG0646	methionine synthase
K09K1_37210	COG1410	methionine synthase
K09K1_37220	COG0527	aspartate kinase activity
K09K1_37230	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
K09K1_37270	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
K09K1_37300	COG0629	single-stranded DNA binding
K09K1_37310	COG2200	EAL domain
K09K1_37310	COG2199	diguanylate cyclase activity
K09K1_37350	COG1450	Type ii and iii secretion system protein
K09K1_37360	COG3409	Peptidoglycan-binding domain 1 protein
K09K1_37360	COG3267	Type II secretory pathway component ExeA
K09K1_37380	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
K09K1_37390	COG1459	type II secretion system
K09K1_37480	COG1077	Cell shape determining protein MreB Mrl
K09K1_37490	COG1792	Involved in formation and maintenance of cell shape
K09K1_37500	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
K09K1_37510	COG0424	maF-like protein
K09K1_37520	COG1530	ribonuclease E activity
K09K1_37530	COG3164	Protein of unknown function
K09K1_37540	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
K09K1_37550	COG0312	modulator of DNA gyrase
K09K1_37560	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
K09K1_37570	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
K09K1_37590	COG0564	pseudouridine synthase activity
K09K1_37600	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
K09K1_37610	COG3028	Belongs to the UPF0307 family
K09K1_37620	COG0312	modulator of DNA gyrase
K09K1_37630	COG2239	Acts as a magnesium transporter
K09K1_37640	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
K09K1_37650	COG1660	Displays ATPase and GTPase activities
K09K1_37660	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
K09K1_37670	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
K09K1_37690	COG1137	ATPase activity
K09K1_37700	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
K09K1_37720	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
K09K1_37720	COG0517	IMP dehydrogenase activity
K09K1_37740	COG1127	ABC transporter
K09K1_37750	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
K09K1_37760	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
K09K1_37770	COG2854	intermembrane phospholipid transfer
K09K1_37790	COG5007	Belongs to the BolA IbaG family
K09K1_37800	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
K09K1_37810	COG0204	Acyl-transferase
K09K1_37820	COG0251	oxidation-reduction process
K09K1_37830	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
K09K1_37840	COG0540	Belongs to the ATCase OTCase family
K09K1_37900	COG0456	acetyltransferase
K09K1_37920	COG0525	valine-tRNA ligase activity
K09K1_37930	COG2927	DNA polymerase III (CHI subunit)
K09K1_37940	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
K09K1_37950	COG0795	lipopolysaccharide-transporting ATPase activity
K09K1_37960	COG0795	lipopolysaccharide-transporting ATPase activity
K09K1_37980	COG4325	translation initiation factor activity
K09K1_37990	COG1028	Short-chain dehydrogenase reductase Sdr
K09K1_38010	COG0726	polysaccharide deacetylase
K09K1_38030	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
K09K1_38040	COG1447	Phosphotransferase system cellobiose-specific component IIA
K09K1_38050	COG1486	melibiose metabolic process
K09K1_38060	COG3394	polysaccharide catabolic process
K09K1_38080	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
K09K1_38230	COG0840	transmembrane signaling receptor activity
K09K1_38320	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
K09K1_38340	COG0220	tRNA (guanine-N7-)-methyltransferase activity
K09K1_38360	COG2066	Belongs to the glutaminase family
K09K1_38370	COG0635	Involved in the biosynthesis of porphyrin-containing compound
K09K1_38380	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
K09K1_38400	COG1872	DUF167
K09K1_38410	COG0762	integral membrane protein
K09K1_38420	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
K09K1_38430	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
K09K1_38460	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
K09K1_38470	COG1678	Uncharacterized ACR, COG1678
K09K1_38480	COG0189	ligase activity
K09K1_38490	COG1385	rRNA (uridine-N3-)-methyltransferase activity
K09K1_38500	COG2356	endonuclease I
K09K1_38510	COG3091	SprT-like family
K09K1_38530	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
K09K1_38540	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
K09K1_38550	COG0583	DNA-binding transcription factor activity
K09K1_38560	COG4771	TonB-dependent receptor
K09K1_38590	COG0191	fructose-bisphosphate aldolase activity
K09K1_38600	COG0668	transmembrane transport
K09K1_38630	COG0583	DNA-binding transcription factor activity
K09K1_38650	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
K09K1_38660	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
K09K1_38670	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
K09K1_38680	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
K09K1_38690	COG3079	Belongs to the UPF0149 family
K09K1_38700	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
K09K1_38710	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
K09K1_38750	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
K09K1_38770	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
K09K1_38780	COG1595	DNA-templated transcription, initiation
K09K1_38810	COG3086	response to oxidative stress
K09K1_38820	COG0481	GTPase activity
K09K1_38830	COG0681	Belongs to the peptidase S26 family
K09K1_38850	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
K09K1_38860	COG1381	Involved in DNA repair and RecF pathway recombination
K09K1_38870	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
K09K1_38880	COG0736	holo-[acyl-carrier-protein] synthase activity
K09K1_38900	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
K09K1_38910	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
K09K1_38930	COG3956	TIGRFAM MazG family protein
K09K1_38940	COG0504	CTP synthase activity
K09K1_38950	COG0148	phosphopyruvate hydratase activity
K09K1_38960	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
K09K1_38970	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
K09K1_38980	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
K09K1_39000	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
K09K1_39010	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
K09K1_39030	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
K09K1_39040	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
K09K1_39050	COG1546	Belongs to the CinA family
K09K1_39060	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
K09K1_39070	COG2137	regulation of response to DNA damage stimulus
K09K1_39080	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
K09K1_39090	COG0527	aspartate kinase activity
K09K1_39220	COG0511	ligase activity, forming carbon-carbon bonds
K09K1_39220	COG5016	pyruvate
K09K1_39230	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
K09K1_39250	COG1238	metal cluster binding
K09K1_39260	COG0612	Peptidase, M16
K09K1_39290	COG1854	S-ribosylhomocysteine lyase activity
K09K1_39300	COG4536	flavin adenine dinucleotide binding
K09K1_39310	COG4137	Cytochrome C assembly protein
K09K1_39320	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
K09K1_39330	COG0228	four-way junction DNA binding
K09K1_39340	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
K09K1_39370	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
K09K1_39380	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
K09K1_39390	COG0237	dephospho-CoA kinase activity
K09K1_39410	COG1459	type II secretion system
K09K1_39420	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
K09K1_39430	COG4969	Belongs to the N-Me-Phe pilin family
K09K1_39440	COG0157	Belongs to the NadC ModD family
K09K1_39470	COG2186	Transcriptional regulator
K09K1_39480	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
K09K1_39490	COG0508	dehydrogenase complex catalyzes the overall conversion of
K09K1_39500	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
K09K1_39530	COG0288	reversible hydration of carbon dioxide
K09K1_39540	COG0659	secondary active sulfate transmembrane transporter activity
K09K1_39550	COG1131	(ABC) transporter
K09K1_39560	COG0842	Transport permease protein
K09K1_39570	COG1560	Kdo2-lipid A biosynthetic process
K09K1_39580	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
K09K1_39590	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
K09K1_39600	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
K09K1_39620	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
K09K1_39630	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
K09K1_39640	COG1489	DNA binding
K09K1_39650	COG1643	Atp-dependent helicase
K09K1_39660	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
K09K1_39670	COG1752	Esterase of the alpha-beta hydrolase superfamily
K09K1_39680	COG1049	propionate catabolic process, 2-methylcitrate cycle
K09K1_39690	COG3112	Uncharacterised protein family (UPF0231)
K09K1_39710	COG0004	ammonium transporteR
K09K1_39720	COG1840	ABC-type Fe3 transport system, periplasmic component
K09K1_39740	COG3842	ATPase activity
K09K1_39750	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
K09K1_39760	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
K09K1_39790	COG2971	BadF BadG BcrA BcrD
K09K1_39810	COG4608	Belongs to the ABC transporter superfamily
K09K1_39820	COG0444	Belongs to the ABC transporter superfamily
K09K1_39830	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
K09K1_39850	COG0747	negative chemotaxis
K09K1_39880	COG0628	permease
K09K1_39930	COG0739	heme binding
K09K1_39940	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
K09K1_39960	COG2027	D-alanyl-D-alanine carboxypeptidase
K09K1_39970	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
K09K1_39980	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
K09K1_39990	COG1534	Rna-binding protein
K09K1_40000	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
K09K1_40010	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
K09K1_40020	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
K09K1_40030	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
K09K1_40040	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
K09K1_40070	COG0779	Required for maturation of 30S ribosomal subunits
K09K1_40080	COG0195	Participates in both transcription termination and antitermination
K09K1_40090	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
K09K1_40100	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
K09K1_40110	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
K09K1_40120	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
K09K1_40130	COG1185	polyribonucleotide nucleotidyltransferase activity
K09K1_40160	COG0534	Mate efflux family protein
K09K1_40210	COG3153	acetyltransferase
K09K1_40270	COG0084	hydrolase, TatD family'
K09K1_40280	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
K09K1_40290	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
K09K1_40300	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
K09K1_40310	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
K09K1_40320	COG0813	purine-nucleoside phosphorylase activity
K09K1_40340	COG0560	Phosphoserine phosphatase
K09K1_40360	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
K09K1_40370	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
K09K1_40380	COG0583	DNA-binding transcription factor activity
K09K1_40400	COG1022	Amp-dependent synthetase and ligase
K09K1_40480	COG0583	DNA-binding transcription factor activity
K09K1_40490	COG1609	Transcriptional regulator
K09K1_40530	COG0598	Magnesium transport protein CorA
K09K1_40540	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
K09K1_40550	COG1349	DNA-binding transcription factor activity
K09K1_40560	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
K09K1_40570	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
K09K1_40580	COG2271	Major facilitator Superfamily
K09K1_40590	COG0584	glycerophosphoryl diester phosphodiesterase
K09K1_40600	COG2171	N-acyltransferase activity
K09K1_40630	COG3141	response to X-ray
K09K1_40680	COG0270	DNA (cytosine-5-)-methyltransferase activity
K09K1_40780	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
K09K1_40790	COG1074	ATP-dependent DNA helicase activity
K09K1_40800	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
K09K1_40820	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
K09K1_40820	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
K09K1_40840	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
K09K1_40850	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
K09K1_40860	COG2166	iron-sulfur cluster assembly
K09K1_40870	COG3706	GGDEF domain
K09K1_40880	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
K09K1_40890	COG0693	protein deglycase activity
K09K1_40900	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
K09K1_40940	COG1595	DNA-templated transcription, initiation
K09K1_40980	COG3056	Lipoprotein
K09K1_40990	COG2813	Specifically methylates the guanine in position
K09K1_41000	COG0271	Belongs to the BolA IbaG family
K09K1_41010	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
K09K1_41020	COG1805	sodium ion transport
K09K1_41030	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
K09K1_41040	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
K09K1_41050	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
K09K1_41060	COG2871	sodium ion transport
K09K1_41070	COG1477	protein flavinylation
K09K1_41090	COG3706	GGDEF domain
K09K1_41090	COG0745	RESPONSE REGULATOR receiver
K09K1_41110	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
K09K1_41210	COG0519	Catalyzes the synthesis of GMP from XMP
K09K1_41220	COG0589	response to stress
K09K1_41230	COG0659	secondary active sulfate transmembrane transporter activity
K09K1_41390	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
K09K1_41440	COG0514	ATP-dependent DNA helicase (RecQ)
K09K1_41450	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
K09K1_41480	COG0733	neurotransmitter:sodium symporter activity
K09K1_41520	COG0442	prolyl-tRNA aminoacylation
K09K1_41530	COG1720	tRNA m6t6A37 methyltransferase activity
K09K1_41540	COG0254	rRNA binding
K09K1_41550	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
K09K1_41600	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
K09K1_41610	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
K09K1_41670	COG3098	single-species biofilm formation
K09K1_41680	COG0564	pseudouridine synthase activity
K09K1_41700	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
K09K1_41710	COG0024	Methionine aminopeptidase
K09K1_41720	COG0052	Belongs to the universal ribosomal protein uS2 family
K09K1_41730	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
K09K1_41740	COG0528	UMP kinase activity
K09K1_41750	COG0233	cytoplasmic translational termination
K09K1_41760	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
K09K1_41770	COG0575	Belongs to the CDS family
K09K1_41780	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
K09K1_41790	COG0750	zinc metalloprotease
K09K1_41810	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
K09K1_41820	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
K09K1_41840	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
K09K1_41850	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
K09K1_41870	COG0587	DNA-directed DNA polymerase activity
K09K1_41880	COG0825	malonyl-CoA metabolic process
K09K1_41910	COG0347	Belongs to the P(II) protein family
K09K1_41920	COG3021	interspecies interaction between organisms
K09K1_41940	COG0741	lytic transglycosylase activity
K09K1_41940	COG1388	LysM domain
K09K1_41950	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K09K1_41960	COG2226	methyltransferase
K09K1_41970	COG0328	RNA-DNA hybrid ribonuclease activity
K09K1_41980	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
K09K1_42040	COG1960	acyl-CoA dehydrogenase activity
K09K1_42050	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
K09K1_42060	COG0121	glutamine amidotransferase
K09K1_42080	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
K09K1_42090	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
K09K1_42100	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
K09K1_42110	COG2233	PERMEase
K09K1_42150	COG1393	Belongs to the ArsC family
K09K1_42160	COG4783	chaperone-mediated protein folding
K09K1_42190	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
K09K1_42220	COG1278	Cold shock
K09K1_42260	COG0330	HflC and HflK could
K09K1_42270	COG4974	Belongs to the 'phage' integrase family
K09K1_42280	COG1278	Cold shock
K09K1_42330	COG1278	Cold shock
K09K1_42360	COG2963	transposase activity
K09K1_42400	COG0210	DNA helicase
K09K1_42530	COG1053	succinate dehydrogenase
K09K1_42550	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
K09K1_42600	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
K09K1_42620	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
K09K1_42660	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
K09K1_42670	COG1393	Belongs to the ArsC family
K09K1_42720	COG2837	iron assimilation
K09K1_42730	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
K09K1_42740	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
K09K1_42750	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
K09K1_42760	COG1334	flagellar protein FlaG
K09K1_42770	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
K09K1_42790	COG1516	flagellar protein fliS
K09K1_42800	COG2204	response regulator
K09K1_42810	COG4191	Histidine kinase
K09K1_42820	COG2204	response regulator
K09K1_42830	COG1677	Flagellar hook-basal body complex protein FliE
K09K1_42850	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
K09K1_42960	COG1987	bacterial-type flagellum assembly
K09K1_42970	COG1684	flagellar biosynthetic protein fliR
K09K1_43010	COG0455	bacterial-type flagellum organization
K09K1_43040	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
K09K1_43050	COG0643	Histidine kinase
K09K1_43050	COG2198	Histidine kinase
K09K1_43060	COG2201	protein-glutamate methylesterase activity
K09K1_43070	COG1192	Involved in chromosome partitioning
K09K1_43090	COG0835	chemotaxis
K09K1_43110	COG4133	protoheme IX ABC transporter activity
K09K1_43120	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
K09K1_43130	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
K09K1_43140	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
K09K1_43150	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
K09K1_43160	COG1138	Cytochrome C-type biogenesis protein
K09K1_43170	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
K09K1_43190	COG3088	subunit of a heme lyase
K09K1_43190	COG4235	cytochrome complex assembly
K09K1_43210	COG2067	long-chain fatty acid transport protein
K09K1_43260	COG0183	Belongs to the thiolase family
K09K1_43270	COG1250	3-hydroxyacyl-CoA dehydrogenase
K09K1_43270	COG1024	Enoyl-CoA hydratase
K09K1_43300	COG2062	phosphohistidine phosphatase, SixA
K09K1_43310	COG2840	Smr protein MutS2
K09K1_43320	COG2890	protein-(glutamine-N5) methyltransferase activity
K09K1_43330	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
K09K1_43340	COG2860	membrane
K09K1_43350	COG3101	peptidyl-lysine hydroxylation
K09K1_43370	COG0431	NADPH-dependent FMN reductase
K09K1_43380	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
K09K1_43380	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
K09K1_43390	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
K09K1_43400	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
K09K1_43410	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
K09K1_43430	COG0101	tRNA pseudouridine synthase activity
K09K1_43440	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
K09K1_43450	COG0285	dihydrofolate synthase activity
K09K1_43460	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
K09K1_43470	COG1286	toxin biosynthetic process
K09K1_43480	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
K09K1_43490	COG0583	DNA-binding transcription factor activity
K09K1_43500	COG0745	RESPONSE REGULATOR receiver
K09K1_43520	COG2832	Protein of unknown function (DUF454)
K09K1_43530	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
K09K1_43550	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
K09K1_43560	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
K09K1_43570	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
K09K1_43590	COG2261	transglycosylase associated protein
K09K1_43600	COG2983	Belongs to the UPF0260 family
K09K1_43610	COG0668	transmembrane transport
K09K1_43620	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
K09K1_43630	COG0346	lactoylglutathione lyase activity
K09K1_43650	COG1785	Belongs to the alkaline phosphatase family
K09K1_43680	COG2226	methyltransferase
K09K1_43710	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
K09K1_43720	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
K09K1_43740	COG3139	Protein of unknown function (DUF1315)
K09K1_43750	COG0252	asparaginase activity
K09K1_43760	COG0616	signal peptide processing
K09K1_43770	COG1902	pentaerythritol trinitrate reductase activity
K09K1_43770	COG0446	pyridine nucleotide-disulphide oxidoreductase
K09K1_43790	COG0778	Nitroreductase
K09K1_43800	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
K09K1_43840	COG0123	including yeast histone deacetylase and acetoin utilization protein
K09K1_43860	COG3083	sulfuric ester hydrolase activity
K09K1_43870	COG3082	Protein of unknown function (DUF1414)
K09K1_43880	COG3081	Nucleoid-associated protein
K09K1_43910	COG1757	Na H antiporter
K09K1_43920	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
K09K1_43930	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
K09K1_43940	COG2095	MarC family integral membrane protein
K09K1_43950	COG1012	belongs to the aldehyde dehydrogenase family
K09K1_43950	COG1454	alcohol dehydrogenase
K09K1_43990	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
K09K1_44030	COG2056	Na+-H+ antiporter family
K09K1_44040	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
K09K1_44050	COG2885	chlorophyll binding
K09K1_44070	COG0346	lactoylglutathione lyase activity
K09K1_44080	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
K09K1_44090	COG4660	Part of a membrane complex involved in electron transport
K09K1_44100	COG4659	FMN binding
K09K1_44110	COG4658	electron transport chain
K09K1_44120	COG4656	Part of a membrane complex involved in electron transport
K09K1_44130	COG2878	Part of a membrane complex involved in electron transport
K09K1_44140	COG4657	Part of a membrane complex involved in electron transport
K09K1_44150	COG1882	Formate acetyltransferase
K09K1_44170	COG0556	nucleotide-excision repair
K09K1_44180	COG2204	response regulator
K09K1_44190	COG2198	Histidine kinase
K09K1_44200	COG0391	Required for morphogenesis under gluconeogenic growth conditions
K09K1_44210	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
K09K1_44220	COG0521	Mo-molybdopterin cofactor biosynthetic process
K09K1_44230	COG0315	cyclic pyranopterin monophosphate synthase activity
K09K1_44240	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
K09K1_44250	COG0314	molybdopterin synthase activity
K09K1_44270	COG0601	transmembrane transport
K09K1_44280	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
K09K1_44290	COG0444	Belongs to the ABC transporter superfamily
K09K1_44310	COG0435	Glutathione S-transferase
K09K1_44330	COG0857	belongs to the CobB CobQ family
K09K1_44330	COG0280	phosphate acetyltransferase
K09K1_44340	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
K09K1_44350	COG3092	negative regulation of chromosome organization
K09K1_44370	COG4120	Belongs to the binding-protein-dependent transport system permease family
K09K1_44380	COG1122	ATPase activity
K09K1_44390	COG0366	Alpha amylase catalytic
K09K1_44400	COG3706	GGDEF domain
K09K1_44410	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
K09K1_44420	COG3318	Belongs to the UPF0149 family
K09K1_44420	COG3012	SEC-C Motif Domain Protein
K09K1_44430	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
K09K1_44440	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
K09K1_44450	COG2186	Transcriptional regulator
K09K1_44490	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
K09K1_44490	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
K09K1_44510	COG0572	uridine kinase
K09K1_44530	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
K09K1_44540	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
K09K1_44550	COG0659	secondary active sulfate transmembrane transporter activity
K09K1_44560	COG1530	ribonuclease E activity
K09K1_44570	COG0564	pseudouridine synthase activity
K09K1_44580	COG0424	maF-like protein
K09K1_44590	COG1399	metal-binding, possibly nucleic acid-binding protein
K09K1_44610	COG0416	fatty acid biosynthetic process
K09K1_44620	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
K09K1_44680	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
K09K1_44690	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
K09K1_44700	COG0470	DNA polymerase III
K09K1_44710	COG0084	hydrolase, TatD family'
K09K1_44720	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
K09K1_44720	COG1263	PTS System
K09K1_44750	COG0733	neurotransmitter:sodium symporter activity
K09K1_44780	COG4667	esterase of the alpha-beta hydrolase superfamily
K09K1_44800	COG0469	pyruvate kinase activity
K09K1_44810	COG1940	carbohydrate kinase activity
K09K1_44820	COG0835	chemotaxis
K09K1_44820	COG0784	Response regulator, receiver
K09K1_44830	COG0587	DNA-directed DNA polymerase activity
K09K1_44860	COG1028	Short-chain dehydrogenase reductase Sdr
K09K1_44870	COG0616	signal peptide processing
K09K1_44880	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
K09K1_44890	COG0539	negative regulation of cytoplasmic translation
K09K1_44910	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
K09K1_44920	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
K09K1_44940	COG4166	transmembrane transport
K09K1_44980	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
K09K1_44980	COG3008	intermembrane lipid transfer
K09K1_44990	COG2995	paraquat-inducible protein a
K09K1_45000	COG3258	Cytochrome c
K09K1_45010	COG2863	cytochrome
K09K1_45080	COG4232	protein-disulfide reductase activity
K09K1_45090	COG3118	belongs to the thioredoxin family
K09K1_45140	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
K09K1_45160	COG1136	(ABC) transporter
K09K1_45160	COG0577	efflux transmembrane transporter activity
K09K1_45170	COG1136	(ABC) transporter
K09K1_45170	COG0577	efflux transmembrane transporter activity
K09K1_45180	COG1136	(ABC) transporter
K09K1_45180	COG0577	efflux transmembrane transporter activity
K09K1_45220	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
K09K1_45280	COG5002	protein histidine kinase activity
K09K1_45280	COG3850	Histidine kinase
K09K1_45290	COG0745	RESPONSE REGULATOR receiver
K09K1_45300	COG0463	Glycosyl transferase, family 2
K09K1_45310	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
K09K1_45350	COG1032	radical SAM domain protein
K09K1_45360	COG5001	Diguanylate cyclase
K09K1_45390	COG0583	DNA-binding transcription factor activity
K09K1_45400	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
K09K1_45420	COG2350	Protein conserved in bacteria
K09K1_45430	COG1607	acyl-coa hydrolase
K09K1_45440	COG2917	probably involved in intracellular septation
K09K1_45480	COG1301	dicarboxylic acid transport
K09K1_45490	COG0318	PFAM AMP-dependent synthetase and ligase
K09K1_45500	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
K09K1_45510	COG0159	tryptophan synthase activity
K09K1_45530	COG0135	phosphoribosylanthranilate isomerase activity
K09K1_45530	COG0134	indole-3-glycerol-phosphate synthase activity
K09K1_45550	COG0512	Glutamine amidotransferase of anthranilate synthase
K09K1_45560	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
K09K1_45580	COG0613	PHP domain protein
K09K1_45590	COG0009	L-threonylcarbamoyladenylate synthase
K09K1_45610	COG1187	pseudouridine synthase activity
K09K1_45650	COG0417	DNA replication proofreading
K09K1_45660	COG2197	response regulator
K09K1_45670	COG0322	excinuclease ABC activity
K09K1_45750	COG0019	diaminopimelate decarboxylase activity
K09K1_45800	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
K09K1_45810	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
K09K1_45820	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
K09K1_45860	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
K09K1_45880	COG0437	4 iron, 4 sulfur cluster binding
K09K1_45890	COG3301	Polysulphide reductase, NrfD
K09K1_45900	COG1138	Cytochrome C-type biogenesis protein
K09K1_45920	COG3088	subunit of a heme lyase
K09K1_45920	COG4235	cytochrome complex assembly
K09K1_45930	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
K09K1_45980	COG2989	Protein conserved in bacteria
K09K1_45990	COG3108	Peptidase M15
K09K1_46000	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K09K1_46030	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
K09K1_46090	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
K09K1_46100	COG0840	transmembrane signaling receptor activity
K09K1_46140	COG1448	Aminotransferase
K09K1_46170	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K09K1_46190	COG0017	Asparaginyl-tRNA synthetase
K09K1_46200	COG0840	transmembrane signaling receptor activity
K09K1_46210	COG0720	synthase
K09K1_46230	COG2200	EAL domain
K09K1_46240	COG1760	l-serine dehydratase
K09K1_46250	COG0814	amino acid
K09K1_46260	COG0494	nUDIX hydrolase
K09K1_46280	COG0784	Response regulator, receiver
K09K1_46280	COG2205	protein histidine kinase activity
K09K1_46290	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
K09K1_46320	COG3106	COG3106 Predicted ATPase
K09K1_46330	COG3768	UPF0283 membrane protein
K09K1_46350	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K09K1_46410	COG4628	conserved protein (DUF2132)
K09K1_46540	COG1335	isochorismatase
K09K1_46660	COG2197	response regulator
K09K1_46670	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
K09K1_46670	COG2205	protein histidine kinase activity
K09K1_46690	COG1472	Belongs to the glycosyl hydrolase 3 family
K09K1_46830	COG2197	response regulator
K09K1_46840	COG2199	diguanylate cyclase activity
K09K1_46840	COG3287	FIST C domain
K09K1_46840	COG2200	EAL domain
K09K1_46850	COG3477	response to acidic pH
K09K1_46900	COG2204	response regulator
K09K1_46990	COG2205	protein histidine kinase activity
K09K1_46990	COG0784	Response regulator, receiver
K09K1_47000	COG2221	Nitrite and sulphite reductase 4Fe-4S
K09K1_47000	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
K09K1_47020	COG0243	molybdopterin cofactor binding
K09K1_47030	COG0437	4 iron, 4 sulfur cluster binding
K09K1_47040	COG3302	dmso reductase anchor subunit
K09K1_47060	COG2433	Pfam Transposase IS66
K09K1_47080	COG0025	NhaP-type Na H and K H
K09K1_47090	COG2985	domain, Protein
K09K1_47110	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
K09K1_47140	COG1289	transmembrane transporter activity
K09K1_47170	COG0387	Pfam Sodium calcium exchanger
K09K1_47180	COG0387	Pfam Sodium calcium exchanger
K09K1_47200	COG0598	Magnesium transport protein CorA
K09K1_47210	COG0076	glutamate decarboxylase activity
K09K1_47220	COG2985	domain, Protein
K09K1_47250	COG3706	GGDEF domain
K09K1_47280	COG4974	Belongs to the 'phage' integrase family
K09K1_47410	COG1403	HNH endonuclease
K09K1_47460	COG2801	Transposase and inactivated derivatives
K09K1_47580	COG1683	Conserved Protein
K09K1_47630	COG2801	Transposase and inactivated derivatives
K09K1_47710	COG0110	maltose O-acetyltransferase activity
K09K1_47730	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
K09K1_47770	COG5507	3-demethylubiquinone-9 3-methyltransferase
K09K1_47780	COG1280	lysine exporter protein (LysE YggA)
K09K1_47790	COG1280	lysine exporter protein (LysE YggA)
K09K1_47810	COG0729	surface antigen
K09K1_47840	COG2272	Belongs to the type-B carboxylesterase lipase family
K09K1_47900	COG2985	domain, Protein
K09K1_47920	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
K09K1_47980	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
K09K1_48010	COG3290	protein histidine kinase activity
K09K1_48020	COG4565	transcriptional regulatory protein
K09K1_48040	COG2207	Transcriptional regulator
K09K1_48050	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
K09K1_48060	COG0363	glucosamine-6-phosphate deaminase activity
K09K1_48070	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
K09K1_48100	COG3284	Transcriptional regulator
K09K1_48110	COG1012	belongs to the aldehyde dehydrogenase family
K09K1_48250	COG4669	(LipO)protein
K09K1_48290	COG3177	Filamentation induced by cAMP protein fic
K09K1_48350	COG2207	Transcriptional regulator
K09K1_48360	COG4792	protein secretion
K09K1_48370	COG4791	protein targeting
K09K1_48380	COG4794	Type iii secretion
K09K1_48390	COG4790	Type iii secretion
K09K1_48400	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
K09K1_48530	COG0457	Tetratricopeptide repeat
K09K1_48570	COG0730	response to heat
K09K1_48640	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
K09K1_48650	COG0372	Belongs to the citrate synthase family
K09K1_48670	COG2828	Protein conserved in bacteria
K09K1_48720	COG0561	phosphatase activity
K09K1_48730	COG0602	queuosine metabolic process
K09K1_48740	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
K09K1_48770	COG0583	DNA-binding transcription factor activity
K09K1_48790	COG0583	DNA-binding transcription factor activity
K09K1_48820	COG0583	DNA-binding transcription factor activity
K09K1_48860	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
K09K1_48870	COG0765	amino acid transport
K09K1_48880	COG1126	abc transporter atp-binding protein
K09K1_48890	COG1410	methionine synthase
K09K1_48890	COG0646	methionine synthase
K09K1_48920	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
K09K1_48930	COG1335	isochorismatase
K09K1_48970	COG2814	Major facilitator Superfamily
K09K1_48980	COG0583	DNA-binding transcription factor activity
K09K1_49000	COG0583	DNA-binding transcription factor activity
K09K1_49010	COG0656	L-ascorbic acid biosynthetic process
K09K1_49030	COG1414	Transcriptional regulator
K09K1_49040	COG2199	diguanylate cyclase activity
K09K1_49040	COG2203	Gaf domain
K09K1_49090	COG2885	chlorophyll binding
K09K1_49130	COG0840	transmembrane signaling receptor activity
K09K1_49140	COG1254	Belongs to the acylphosphatase family
K09K1_49150	COG2920	part of a sulfur-relay system
K09K1_49170	COG0670	Belongs to the BI1 family
K09K1_49180	COG1126	abc transporter atp-binding protein
K09K1_49190	COG0765	amino acid transport
K09K1_49200	COG4597	amino acid ABC transporter
K09K1_49220	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
K09K1_49240	COG1666	GTP binding
K09K1_49250	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
K09K1_49300	COG3008	intermembrane lipid transfer
K09K1_49310	COG2995	paraquat-inducible protein a
K09K1_49320	COG1132	(ABC) transporter
K09K1_49330	COG1956	GAF domain-containing protein
K09K1_49340	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
K09K1_49370	COG0308	aminopeptidase N
K09K1_49380	COG2902	Dehydrogenase
K09K1_49390	COG0167	dihydroorotate dehydrogenase activity
K09K1_49410	COG0116	Belongs to the methyltransferase superfamily
K09K1_49410	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
K09K1_49460	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
K09K1_49470	COG1067	ATP-dependent peptidase activity
K09K1_49480	COG3120	sequence-specific DNA binding
K09K1_49530	COG4128	Pfam Zonular occludens toxin