locus-tag	class	description
EEA47_00035	COG0247	lactate metabolic process
EEA47_00035	COG0277	FAD linked oxidase domain protein
EEA47_00050	COG2986	histidine ammonia-lyase
EEA47_00055	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
EEA47_00060	COG0010	Belongs to the arginase family
EEA47_00065	COG1228	amidohydrolase
EEA47_00085	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EEA47_00095	COG0291	Belongs to the bacterial ribosomal protein bL35 family
EEA47_00105	COG0393	Putative heavy-metal-binding
EEA47_00140	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EEA47_00145	COG0072	phenylalanine-tRNA ligase activity
EEA47_00145	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EEA47_00155	COG0776	regulation of translation
EEA47_00165	COG0500	methyltransferase
EEA47_00170	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
EEA47_00175	COG0295	cytidine deaminase activity
EEA47_00180	COG1346	cytolysis
EEA47_00185	COG1380	Effector of murein hydrolase LrgA
EEA47_00190	COG2925	Exonuclease
EEA47_00195	COG1823	symporter activity
EEA47_00200	COG0702	epimerase
EEA47_00205	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
EEA47_00210	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
EEA47_00230	COG2988	succinylglutamate desuccinylase activity
EEA47_00235	COG4139	cobalamin transport
EEA47_00240	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
EEA47_00260	COG0583	DNA-binding transcription factor activity
EEA47_00270	COG1451	nucleotide metabolic process
EEA47_00275	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
EEA47_00305	COG3938	Belongs to the proline racemase family
EEA47_00320	COG2423	ornithine cyclodeaminase activity
EEA47_00325	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EEA47_00330	COG3842	ATPase activity
EEA47_00335	COG1176	ABC-type spermidine putrescine transport system, permease component I
EEA47_00340	COG1177	transmembrane transport
EEA47_00355	COG3291	Pkd domain containing protein
EEA47_00375	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EEA47_00380	COG0601	transmembrane transport
EEA47_00390	COG2195	Cleaves the N-terminal amino acid of tripeptides
EEA47_00400	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
EEA47_00410	COG0625	glutathione transferase activity
EEA47_00460	COG3755	Protein conserved in bacteria
EEA47_00485	COG1742	UPF0060 membrane protein
EEA47_00500	COG1757	Na H antiporter
EEA47_00505	COG0174	glutamine synthetase
EEA47_00515	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
EEA47_00520	COG1396	sequence-specific DNA binding
EEA47_00520	COG1917	Cupin 2, conserved barrel domain protein
EEA47_00525	COG1012	belongs to the aldehyde dehydrogenase family
EEA47_00530	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EEA47_00540	COG2957	Belongs to the agmatine deiminase family
EEA47_00545	COG1012	belongs to the aldehyde dehydrogenase family
EEA47_00550	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EEA47_00555	COG2200	EAL domain
EEA47_00565	COG1846	Transcriptional regulator
EEA47_00570	COG2315	Protein conserved in bacteria
EEA47_00610	COG3063	Type IV pilus biogenesis stability protein PilW
EEA47_00615	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
EEA47_00630	COG1560	Kdo2-lipid A biosynthetic process
EEA47_00635	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
EEA47_00640	COG1280	lysine exporter protein (LysE YggA)
EEA47_00650	COG1115	amino acid carrier protein
EEA47_00675	COG1368	sulfuric ester hydrolase activity
EEA47_00680	COG2113	Glycine betaine
EEA47_00685	COG4176	ABC-type proline glycine betaine transport system permease component
EEA47_00690	COG4175	Glycine betaine
EEA47_00705	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EEA47_00710	COG0456	acetyltransferase
EEA47_00715	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EEA47_00720	COG0662	Cupin 2, conserved barrel domain protein
EEA47_00725	COG0527	aspartate kinase activity
EEA47_00730	COG3119	arylsulfatase activity
EEA47_00745	COG0641	radical SAM
EEA47_00760	COG3119	arylsulfatase activity
EEA47_00785	COG1538	Outer membrane efflux protein
EEA47_00800	COG1349	DNA-binding transcription factor activity
EEA47_00805	COG0673	inositol 2-dehydrogenase activity
EEA47_00810	COG4702	Belongs to the UPF0303 family
EEA47_00835	COG0471	metal ion transport
EEA47_00850	COG5001	Diguanylate cyclase
EEA47_00850	COG3300	MHYT domain
EEA47_00865	COG1328	CTP reductase activity
EEA47_00870	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EEA47_00880	COG0861	Integral membrane protein TerC family
EEA47_00890	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
EEA47_00900	COG0814	amino acid
EEA47_00915	COG1120	ATPase activity
EEA47_00920	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EEA47_00930	COG4774	siderophore transport
EEA47_00940	COG1132	(ABC) transporter
EEA47_00945	COG1132	(ABC) transporter
EEA47_00960	COG0583	DNA-binding transcription factor activity
EEA47_00965	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
EEA47_00985	COG0443	Heat shock 70 kDa protein
EEA47_00990	COG0443	Heat shock 70 kDa protein
EEA47_01035	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
EEA47_01040	COG1643	Atp-dependent helicase
EEA47_01055	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EEA47_01065	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EEA47_01070	COG1215	transferase activity, transferring glycosyl groups
EEA47_01075	COG0438	transferase activity, transferring glycosyl groups
EEA47_01105	COG0438	transferase activity, transferring glycosyl groups
EEA47_01110	COG0438	transferase activity, transferring glycosyl groups
EEA47_01115	COG2204	response regulator
EEA47_01150	COG1793	dna ligase
EEA47_01160	COG0534	Mate efflux family protein
EEA47_01165	COG0307	riboflavin synthase, alpha
EEA47_01175	COG3001	Fructosamine kinase
EEA47_01185	COG3706	GGDEF domain
EEA47_01195	COG0791	NLP P60 protein
EEA47_01225	COG3148	PFAM DTW domain containing protein
EEA47_01230	COG1940	carbohydrate kinase activity
EEA47_01240	COG0303	'Molybdopterin
EEA47_01245	COG0746	molybdenum cofactor guanylyltransferase activity
EEA47_01250	COG3842	ATPase activity
EEA47_01265	COG2204	response regulator
EEA47_01270	COG4191	Histidine kinase
EEA47_01280	COG0488	(ABC) transporter
EEA47_01285	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EEA47_01305	COG3381	protein complex oligomerization
EEA47_01315	COG0243	molybdopterin cofactor binding
EEA47_01315	COG3383	formate dehydrogenase (NAD+) activity
EEA47_01320	COG0437	4 iron, 4 sulfur cluster binding
EEA47_01350	COG0004	ammonium transporteR
EEA47_01355	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
EEA47_01360	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
EEA47_01370	COG1177	transmembrane transport
EEA47_01380	COG3842	ATPase activity
EEA47_01405	COG0589	response to stress
EEA47_01410	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EEA47_01425	COG2217	Heavy metal translocating P-type atpase
EEA47_01435	COG2010	Cytochrome c
EEA47_01450	COG3278	Belongs to the heme-copper respiratory oxidase family
EEA47_01465	COG2205	protein histidine kinase activity
EEA47_01465	COG0784	Response regulator, receiver
EEA47_01480	COG3120	sequence-specific DNA binding
EEA47_01485	COG1067	ATP-dependent peptidase activity
EEA47_01490	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EEA47_01505	COG0488	(ABC) transporter
EEA47_01515	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
EEA47_01515	COG0116	Belongs to the methyltransferase superfamily
EEA47_01525	COG0167	dihydroorotate dehydrogenase activity
EEA47_01530	COG2902	Dehydrogenase
EEA47_01540	COG0308	aminopeptidase N
EEA47_01555	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
EEA47_01560	COG1956	GAF domain-containing protein
EEA47_01565	COG1132	(ABC) transporter
EEA47_01570	COG2995	paraquat-inducible protein a
EEA47_01575	COG3008	intermembrane lipid transfer
EEA47_01600	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EEA47_01605	COG1666	GTP binding
EEA47_01620	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EEA47_01625	COG4597	amino acid ABC transporter
EEA47_01630	COG0765	amino acid transport
EEA47_01635	COG1126	abc transporter atp-binding protein
EEA47_01640	COG0670	Belongs to the BI1 family
EEA47_01650	COG2920	part of a sulfur-relay system
EEA47_01655	COG1254	Belongs to the acylphosphatase family
EEA47_01680	COG2885	chlorophyll binding
EEA47_01715	COG2199	diguanylate cyclase activity
EEA47_01715	COG2203	Gaf domain
EEA47_01720	COG1414	Transcriptional regulator
EEA47_01730	COG0656	L-ascorbic acid biosynthetic process
EEA47_01735	COG0583	DNA-binding transcription factor activity
EEA47_01740	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EEA47_01745	COG0583	DNA-binding transcription factor activity
EEA47_01750	COG2814	Major facilitator Superfamily
EEA47_01770	COG1335	isochorismatase
EEA47_01775	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EEA47_01790	COG0646	methionine synthase
EEA47_01790	COG1410	methionine synthase
EEA47_01795	COG1126	abc transporter atp-binding protein
EEA47_01800	COG0765	amino acid transport
EEA47_01805	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EEA47_01820	COG0583	DNA-binding transcription factor activity
EEA47_01835	COG0583	DNA-binding transcription factor activity
EEA47_01845	COG0583	DNA-binding transcription factor activity
EEA47_01860	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
EEA47_01865	COG0602	queuosine metabolic process
EEA47_01870	COG0561	phosphatase activity
EEA47_01895	COG2828	Protein conserved in bacteria
EEA47_01905	COG0372	Belongs to the citrate synthase family
EEA47_01910	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
EEA47_01945	COG0730	response to heat
EEA47_01950	COG2358	TRAP transporter, solute receptor (TAXI family
EEA47_01970	COG0457	Tetratricopeptide repeat
EEA47_02040	COG4790	Type iii secretion
EEA47_02045	COG4794	Type iii secretion
EEA47_02050	COG4791	protein targeting
EEA47_02055	COG4792	protein secretion
EEA47_02060	COG2207	Transcriptional regulator
EEA47_02090	COG3177	Filamentation induced by cAMP protein fic
EEA47_02110	COG4669	(LipO)protein
EEA47_02180	COG1012	belongs to the aldehyde dehydrogenase family
EEA47_02185	COG3284	Transcriptional regulator
EEA47_02210	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
EEA47_02215	COG0363	glucosamine-6-phosphate deaminase activity
EEA47_02220	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EEA47_02225	COG2207	Transcriptional regulator
EEA47_02235	COG4565	transcriptional regulatory protein
EEA47_02240	COG3290	protein histidine kinase activity
EEA47_02255	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EEA47_02285	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
EEA47_02295	COG2985	domain, Protein
EEA47_02320	COG2272	Belongs to the type-B carboxylesterase lipase family
EEA47_02325	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EEA47_02330	COG0729	surface antigen
EEA47_02340	COG1280	lysine exporter protein (LysE YggA)
EEA47_02345	COG1280	lysine exporter protein (LysE YggA)
EEA47_02350	COG5507	3-demethylubiquinone-9 3-methyltransferase
EEA47_02370	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EEA47_02375	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EEA47_02380	COG0110	maltose O-acetyltransferase activity
EEA47_02480	COG1714	RDD family
EEA47_02600	COG0494	nUDIX hydrolase
EEA47_02635	COG1683	Conserved Protein
EEA47_02795	COG1278	Cold shock
EEA47_02840	COG0582	viral genome integration into host DNA
EEA47_03215	COG0456	acetyltransferase
EEA47_03295	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EEA47_03305	COG3768	UPF0283 membrane protein
EEA47_03310	COG3106	COG3106 Predicted ATPase
EEA47_03330	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EEA47_03335	COG0784	Response regulator, receiver
EEA47_03335	COG2205	protein histidine kinase activity
EEA47_03345	COG0494	nUDIX hydrolase
EEA47_03350	COG0814	amino acid
EEA47_03355	COG1760	l-serine dehydratase
EEA47_03360	COG2200	EAL domain
EEA47_03370	COG0720	synthase
EEA47_03375	COG0840	transmembrane signaling receptor activity
EEA47_03380	COG0017	Asparaginyl-tRNA synthetase
EEA47_03390	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EEA47_03405	COG1448	Aminotransferase
EEA47_03425	COG0840	transmembrane signaling receptor activity
EEA47_03430	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EEA47_03460	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
EEA47_03475	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EEA47_03480	COG3108	Peptidase M15
EEA47_03485	COG2989	Protein conserved in bacteria
EEA47_03510	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EEA47_03520	COG3088	subunit of a heme lyase
EEA47_03520	COG4235	cytochrome complex assembly
EEA47_03530	COG1138	Cytochrome C-type biogenesis protein
EEA47_03535	COG3301	Polysulphide reductase, NrfD
EEA47_03540	COG0437	4 iron, 4 sulfur cluster binding
EEA47_03550	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
EEA47_03570	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EEA47_03575	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EEA47_03605	COG0019	diaminopimelate decarboxylase activity
EEA47_03655	COG0322	excinuclease ABC activity
EEA47_03660	COG2197	response regulator
EEA47_03665	COG0417	DNA replication proofreading
EEA47_03685	COG1187	pseudouridine synthase activity
EEA47_03695	COG0009	L-threonylcarbamoyladenylate synthase
EEA47_03700	COG0613	PHP domain protein
EEA47_03710	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EEA47_03715	COG0512	Glutamine amidotransferase of anthranilate synthase
EEA47_03725	COG0135	phosphoribosylanthranilate isomerase activity
EEA47_03725	COG0134	indole-3-glycerol-phosphate synthase activity
EEA47_03735	COG0159	tryptophan synthase activity
EEA47_03740	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EEA47_03745	COG0318	PFAM AMP-dependent synthetase and ligase
EEA47_03755	COG1301	dicarboxylic acid transport
EEA47_03775	COG2917	probably involved in intracellular septation
EEA47_03785	COG2350	Protein conserved in bacteria
EEA47_03795	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EEA47_03800	COG0583	DNA-binding transcription factor activity
EEA47_03815	COG5001	Diguanylate cyclase
EEA47_03820	COG1032	radical SAM domain protein
EEA47_03840	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
EEA47_03845	COG0463	Glycosyl transferase, family 2
EEA47_03850	COG0745	RESPONSE REGULATOR receiver
EEA47_03855	COG5002	protein histidine kinase activity
EEA47_03855	COG3850	Histidine kinase
EEA47_03910	COG0577	efflux transmembrane transporter activity
EEA47_03910	COG1136	(ABC) transporter
EEA47_03920	COG1136	(ABC) transporter
EEA47_03920	COG0577	efflux transmembrane transporter activity
EEA47_03930	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EEA47_03950	COG3118	belongs to the thioredoxin family
EEA47_03955	COG4232	protein-disulfide reductase activity
EEA47_03990	COG2863	cytochrome
EEA47_03995	COG3258	Cytochrome c
EEA47_04000	COG2995	paraquat-inducible protein a
EEA47_04005	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
EEA47_04005	COG3008	intermembrane lipid transfer
EEA47_04025	COG4166	transmembrane transport
EEA47_04035	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
EEA47_04040	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
EEA47_04050	COG0539	negative regulation of cytoplasmic translation
EEA47_04055	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
EEA47_04060	COG0616	signal peptide processing
EEA47_04065	COG1028	Short-chain dehydrogenase reductase Sdr
EEA47_04080	COG0587	DNA-directed DNA polymerase activity
EEA47_04085	COG0784	Response regulator, receiver
EEA47_04085	COG0835	chemotaxis
EEA47_04090	COG1940	carbohydrate kinase activity
EEA47_04095	COG0469	pyruvate kinase activity
EEA47_04100	COG4667	esterase of the alpha-beta hydrolase superfamily
EEA47_04115	COG0733	neurotransmitter:sodium symporter activity
EEA47_04130	COG1263	PTS System
EEA47_04130	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EEA47_04135	COG0084	hydrolase, TatD family'
EEA47_04140	COG0470	DNA polymerase III
EEA47_04145	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EEA47_04150	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EEA47_04180	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EEA47_04185	COG0416	fatty acid biosynthetic process
EEA47_04195	COG1399	metal-binding, possibly nucleic acid-binding protein
EEA47_04200	COG0424	maF-like protein
EEA47_04205	COG0564	pseudouridine synthase activity
EEA47_04215	COG1530	ribonuclease E activity
EEA47_04225	COG0659	secondary active sulfate transmembrane transporter activity
EEA47_04235	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EEA47_04240	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
EEA47_04250	COG0572	uridine kinase
EEA47_04260	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EEA47_04260	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EEA47_04270	COG2186	Transcriptional regulator
EEA47_04275	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
EEA47_04280	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
EEA47_04285	COG3318	Belongs to the UPF0149 family
EEA47_04285	COG3012	SEC-C Motif Domain Protein
EEA47_04290	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EEA47_04295	COG3706	GGDEF domain
EEA47_04300	COG0366	Alpha amylase catalytic
EEA47_04305	COG1122	ATPase activity
EEA47_04310	COG4120	Belongs to the binding-protein-dependent transport system permease family
EEA47_04320	COG3092	negative regulation of chromosome organization
EEA47_04325	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EEA47_04330	COG0857	belongs to the CobB CobQ family
EEA47_04330	COG0280	phosphate acetyltransferase
EEA47_04340	COG0435	Glutathione S-transferase
EEA47_04350	COG0444	Belongs to the ABC transporter superfamily
EEA47_04355	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EEA47_04360	COG0601	transmembrane transport
EEA47_04370	COG0314	molybdopterin synthase activity
EEA47_04375	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
EEA47_04380	COG0315	cyclic pyranopterin monophosphate synthase activity
EEA47_04385	COG0521	Mo-molybdopterin cofactor biosynthetic process
EEA47_04390	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EEA47_04395	COG0391	Required for morphogenesis under gluconeogenic growth conditions
EEA47_04400	COG2198	Histidine kinase
EEA47_04405	COG2204	response regulator
EEA47_04410	COG0556	nucleotide-excision repair
EEA47_04420	COG1882	Formate acetyltransferase
EEA47_04425	COG4657	Part of a membrane complex involved in electron transport
EEA47_04430	COG2878	Part of a membrane complex involved in electron transport
EEA47_04435	COG4656	Part of a membrane complex involved in electron transport
EEA47_04440	COG4658	electron transport chain
EEA47_04445	COG4659	FMN binding
EEA47_04450	COG4660	Part of a membrane complex involved in electron transport
EEA47_04455	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EEA47_04460	COG0346	lactoylglutathione lyase activity
EEA47_04470	COG2885	chlorophyll binding
EEA47_04480	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EEA47_04485	COG2056	Na+-H+ antiporter family
EEA47_04495	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
EEA47_04515	COG1012	belongs to the aldehyde dehydrogenase family
EEA47_04515	COG1454	alcohol dehydrogenase
EEA47_04520	COG2095	MarC family integral membrane protein
EEA47_04525	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EEA47_04530	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EEA47_04535	COG1757	Na H antiporter
EEA47_04550	COG3081	Nucleoid-associated protein
EEA47_04555	COG3082	Protein of unknown function (DUF1414)
EEA47_04570	COG0123	including yeast histone deacetylase and acetoin utilization protein
EEA47_04585	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EEA47_04590	COG0778	Nitroreductase
EEA47_04600	COG1902	pentaerythritol trinitrate reductase activity
EEA47_04600	COG0446	pyridine nucleotide-disulphide oxidoreductase
EEA47_04605	COG0616	signal peptide processing
EEA47_04610	COG0252	asparaginase activity
EEA47_04615	COG3139	Protein of unknown function (DUF1315)
EEA47_04625	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EEA47_04630	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EEA47_04645	COG2226	methyltransferase
EEA47_04665	COG1785	Belongs to the alkaline phosphatase family
EEA47_04675	COG0346	lactoylglutathione lyase activity
EEA47_04680	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
EEA47_04685	COG0668	transmembrane transport
EEA47_04690	COG2983	Belongs to the UPF0260 family
EEA47_04695	COG2261	transglycosylase associated protein
EEA47_04705	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EEA47_04710	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EEA47_04725	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EEA47_04730	COG2832	Protein of unknown function (DUF454)
EEA47_04740	COG0745	RESPONSE REGULATOR receiver
EEA47_04745	COG0583	DNA-binding transcription factor activity
EEA47_04750	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EEA47_04755	COG1286	toxin biosynthetic process
EEA47_04760	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
EEA47_04765	COG0285	dihydrofolate synthase activity
EEA47_04770	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EEA47_04780	COG0101	tRNA pseudouridine synthase activity
EEA47_04790	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EEA47_04795	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EEA47_04805	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EEA47_04810	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EEA47_04810	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
EEA47_04815	COG0431	NADPH-dependent FMN reductase
EEA47_04830	COG3101	peptidyl-lysine hydroxylation
EEA47_04840	COG2860	membrane
EEA47_04845	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
EEA47_04850	COG2890	protein-(glutamine-N5) methyltransferase activity
EEA47_04855	COG2840	Smr protein MutS2
EEA47_04860	COG2062	phosphohistidine phosphatase, SixA
EEA47_04875	COG1024	Enoyl-CoA hydratase
EEA47_04875	COG1250	3-hydroxyacyl-CoA dehydrogenase
EEA47_04880	COG0183	Belongs to the thiolase family
EEA47_04905	COG2067	long-chain fatty acid transport protein
EEA47_04915	COG3088	subunit of a heme lyase
EEA47_04915	COG4235	cytochrome complex assembly
EEA47_04925	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EEA47_04930	COG1138	Cytochrome C-type biogenesis protein
EEA47_04935	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
EEA47_04940	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EEA47_04945	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EEA47_04950	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EEA47_04955	COG4133	protoheme IX ABC transporter activity
EEA47_04970	COG0835	chemotaxis
EEA47_04980	COG1192	Involved in chromosome partitioning
EEA47_04985	COG2201	protein-glutamate methylesterase activity
EEA47_04990	COG2198	Histidine kinase
EEA47_04990	COG0784	Response regulator, receiver
EEA47_04990	COG0643	Histidine kinase
EEA47_04995	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
EEA47_05035	COG1987	bacterial-type flagellum assembly
EEA47_05090	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EEA47_05100	COG1677	Flagellar hook-basal body complex protein FliE
EEA47_05120	COG1516	flagellar protein fliS
EEA47_05130	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
EEA47_05135	COG1334	flagellar protein FlaG
EEA47_05140	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EEA47_05145	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EEA47_05155	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EEA47_05160	COG2837	iron assimilation
EEA47_05185	COG1393	Belongs to the ArsC family
EEA47_05190	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EEA47_05205	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
EEA47_05210	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EEA47_05220	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EEA47_05235	COG4783	chaperone-mediated protein folding
EEA47_05240	COG1393	Belongs to the ArsC family
EEA47_05260	COG2233	PERMEase
EEA47_05265	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
EEA47_05270	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
EEA47_05275	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EEA47_05280	COG0121	glutamine amidotransferase
EEA47_05285	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
EEA47_05290	COG1960	acyl-CoA dehydrogenase activity
EEA47_05325	COG0328	RNA-DNA hybrid ribonuclease activity
EEA47_05330	COG2226	methyltransferase
EEA47_05335	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EEA47_05340	COG1388	LysM domain
EEA47_05340	COG0741	lytic transglycosylase activity
EEA47_05350	COG3021	interspecies interaction between organisms
EEA47_05355	COG0347	Belongs to the P(II) protein family
EEA47_05370	COG0825	malonyl-CoA metabolic process
EEA47_05375	COG0587	DNA-directed DNA polymerase activity
EEA47_05385	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EEA47_05390	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EEA47_05400	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EEA47_05405	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
EEA47_05415	COG0750	zinc metalloprotease
EEA47_05420	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
EEA47_05425	COG0575	Belongs to the CDS family
EEA47_05430	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EEA47_05435	COG0233	cytoplasmic translational termination
EEA47_05440	COG0528	UMP kinase activity
EEA47_05445	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EEA47_05450	COG0052	Belongs to the universal ribosomal protein uS2 family
EEA47_05455	COG0024	Methionine aminopeptidase
EEA47_05460	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
EEA47_05475	COG0564	pseudouridine synthase activity
EEA47_05480	COG3098	single-species biofilm formation
EEA47_05515	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EEA47_05520	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EEA47_05545	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
EEA47_05555	COG0254	rRNA binding
EEA47_05560	COG1720	tRNA m6t6A37 methyltransferase activity
EEA47_05565	COG0442	prolyl-tRNA aminoacylation
EEA47_05585	COG0733	neurotransmitter:sodium symporter activity
EEA47_05600	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EEA47_05605	COG0514	ATP-dependent DNA helicase (RecQ)
EEA47_05610	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EEA47_05630	COG1477	protein flavinylation
EEA47_05635	COG2871	sodium ion transport
EEA47_05640	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
EEA47_05645	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
EEA47_05650	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
EEA47_05655	COG1805	sodium ion transport
EEA47_05660	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
EEA47_05665	COG0271	Belongs to the BolA IbaG family
EEA47_05670	COG2813	Specifically methylates the guanine in position
EEA47_05675	COG3056	Lipoprotein
EEA47_05695	COG1595	DNA-templated transcription, initiation
EEA47_05715	COG3248	Nucleoside-binding outer membrane protein
EEA47_05720	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EEA47_05725	COG0693	protein deglycase activity
EEA47_05730	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EEA47_05735	COG3706	GGDEF domain
EEA47_05740	COG2166	iron-sulfur cluster assembly
EEA47_05745	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EEA47_05750	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
EEA47_05765	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
EEA47_05765	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EEA47_05785	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EEA47_05790	COG1074	ATP-dependent DNA helicase activity
EEA47_05800	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
EEA47_05820	COG3141	response to X-ray
EEA47_05835	COG2171	N-acyltransferase activity
EEA47_05840	COG0584	glycerophosphoryl diester phosphodiesterase
EEA47_05845	COG2271	Major facilitator Superfamily
EEA47_05855	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EEA47_05860	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EEA47_05865	COG1349	DNA-binding transcription factor activity
EEA47_05870	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EEA47_05875	COG0598	Magnesium transport protein CorA
EEA47_05895	COG1609	Transcriptional regulator
EEA47_05900	COG0583	DNA-binding transcription factor activity
EEA47_05940	COG1022	Amp-dependent synthetase and ligase
EEA47_05950	COG0583	DNA-binding transcription factor activity
EEA47_05955	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EEA47_05960	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
EEA47_05970	COG0560	Phosphoserine phosphatase
EEA47_05980	COG0813	purine-nucleoside phosphorylase activity
EEA47_05985	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
EEA47_05990	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
EEA47_05995	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
EEA47_06000	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EEA47_06005	COG0084	hydrolase, TatD family'
EEA47_06035	COG3153	acetyltransferase
EEA47_06040	COG3154	lipid carrier protein
EEA47_06055	COG0826	peptidase U32
EEA47_06060	COG0826	peptidase U32
EEA47_06065	COG0534	Mate efflux family protein
EEA47_06080	COG1185	polyribonucleotide nucleotidyltransferase activity
EEA47_06085	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
EEA47_06090	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EEA47_06095	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EEA47_06100	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EEA47_06105	COG0195	Participates in both transcription termination and antitermination
EEA47_06110	COG0779	Required for maturation of 30S ribosomal subunits
EEA47_06125	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EEA47_06135	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EEA47_06140	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EEA47_06145	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EEA47_06150	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
EEA47_06155	COG1534	Rna-binding protein
EEA47_06160	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EEA47_06165	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
EEA47_06170	COG2027	D-alanyl-D-alanine carboxypeptidase
EEA47_06180	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EEA47_06185	COG0739	heme binding
EEA47_06210	COG0628	permease
EEA47_06220	COG0784	Response regulator, receiver
EEA47_06220	COG2205	protein histidine kinase activity
EEA47_06225	COG0747	negative chemotaxis
EEA47_06235	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EEA47_06240	COG0444	Belongs to the ABC transporter superfamily
EEA47_06245	COG4608	Belongs to the ABC transporter superfamily
EEA47_06255	COG2971	BadF BadG BcrA BcrD
EEA47_06270	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EEA47_06275	COG3842	ATPase activity
EEA47_06285	COG1840	ABC-type Fe3 transport system, periplasmic component
EEA47_06290	COG0004	ammonium transporteR
EEA47_06300	COG3112	Uncharacterised protein family (UPF0231)
EEA47_06305	COG1049	propionate catabolic process, 2-methylcitrate cycle
EEA47_06310	COG1752	Esterase of the alpha-beta hydrolase superfamily
EEA47_06315	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EEA47_06320	COG1643	Atp-dependent helicase
EEA47_06325	COG1489	DNA binding
EEA47_06335	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EEA47_06345	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EEA47_06350	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
EEA47_06355	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
EEA47_06360	COG1560	Kdo2-lipid A biosynthetic process
EEA47_06370	COG0842	Transport permease protein
EEA47_06375	COG1131	(ABC) transporter
EEA47_06380	COG0659	secondary active sulfate transmembrane transporter activity
EEA47_06385	COG0288	reversible hydration of carbon dioxide
EEA47_06400	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EEA47_06405	COG0508	dehydrogenase complex catalyzes the overall conversion of
EEA47_06410	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
EEA47_06415	COG2186	Transcriptional regulator
EEA47_06425	COG0157	Belongs to the NadC ModD family
EEA47_06435	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EEA47_06440	COG1459	type II secretion system
EEA47_06450	COG0237	dephospho-CoA kinase activity
EEA47_06455	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
EEA47_06460	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
EEA47_06475	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EEA47_06480	COG0228	four-way junction DNA binding
EEA47_06485	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EEA47_06490	COG4137	Cytochrome C assembly protein
EEA47_06495	COG4536	flavin adenine dinucleotide binding
EEA47_06500	COG1854	S-ribosylhomocysteine lyase activity
EEA47_06510	COG2918	glutathione biosynthetic process
EEA47_06515	COG0612	Peptidase, M16
EEA47_06520	COG1238	metal cluster binding
EEA47_06530	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
EEA47_06535	COG0511	ligase activity, forming carbon-carbon bonds
EEA47_06535	COG5016	pyruvate
EEA47_06540	COG3630	sodium ion export across plasma membrane
EEA47_06600	COG0527	aspartate kinase activity
EEA47_06605	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EEA47_06610	COG2137	regulation of response to DNA damage stimulus
EEA47_06620	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EEA47_06625	COG1546	Belongs to the CinA family
EEA47_06630	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EEA47_06635	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EEA47_06645	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
EEA47_06650	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
EEA47_06660	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
EEA47_06665	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
EEA47_06670	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
EEA47_06675	COG0148	phosphopyruvate hydratase activity
EEA47_06680	COG0504	CTP synthase activity
EEA47_06685	COG3956	TIGRFAM MazG family protein
EEA47_06690	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EEA47_06700	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EEA47_06720	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
EEA47_06725	COG1381	Involved in DNA repair and RecF pathway recombination
EEA47_06730	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EEA47_06740	COG0681	Belongs to the peptidase S26 family
EEA47_06745	COG0481	GTPase activity
EEA47_06750	COG3086	response to oxidative stress
EEA47_06765	COG1595	DNA-templated transcription, initiation
EEA47_06775	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
EEA47_06785	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
EEA47_06805	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EEA47_06810	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EEA47_06815	COG3079	Belongs to the UPF0149 family
EEA47_06825	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
EEA47_06835	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EEA47_06840	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
EEA47_06845	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EEA47_06855	COG0583	DNA-binding transcription factor activity
EEA47_06870	COG0668	transmembrane transport
EEA47_06875	COG0191	fructose-bisphosphate aldolase activity
EEA47_06890	COG4771	TonB-dependent receptor
EEA47_06895	COG0583	DNA-binding transcription factor activity
EEA47_06900	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EEA47_06910	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EEA47_06920	COG3091	SprT-like family
EEA47_06925	COG2356	endonuclease I
EEA47_06930	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EEA47_06935	COG0189	ligase activity
EEA47_06940	COG1678	Uncharacterized ACR, COG1678
EEA47_06945	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EEA47_06960	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EEA47_06965	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EEA47_06970	COG0762	integral membrane protein
EEA47_06975	COG1872	DUF167
EEA47_06985	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
EEA47_06990	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EEA47_06995	COG2066	Belongs to the glutaminase family
EEA47_07005	COG0220	tRNA (guanine-N7-)-methyltransferase activity
EEA47_07015	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
EEA47_07140	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
EEA47_07145	COG1609	Transcriptional regulator
EEA47_07150	COG3394	polysaccharide catabolic process
EEA47_07155	COG1486	melibiose metabolic process
EEA47_07160	COG1447	Phosphotransferase system cellobiose-specific component IIA
EEA47_07165	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EEA47_07170	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EEA47_07175	COG0726	polysaccharide deacetylase
EEA47_07185	COG1028	Short-chain dehydrogenase reductase Sdr
EEA47_07200	COG0795	lipopolysaccharide-transporting ATPase activity
EEA47_07205	COG0795	lipopolysaccharide-transporting ATPase activity
EEA47_07210	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EEA47_07215	COG2927	DNA polymerase III (CHI subunit)
EEA47_07220	COG0525	valine-tRNA ligase activity
EEA47_07230	COG0456	acetyltransferase
EEA47_07260	COG0540	Belongs to the ATCase OTCase family
EEA47_07265	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
EEA47_07270	COG0251	oxidation-reduction process
EEA47_07275	COG0204	Acyl-transferase
EEA47_07280	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EEA47_07285	COG5007	Belongs to the BolA IbaG family
EEA47_07295	COG2854	intermembrane phospholipid transfer
EEA47_07300	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
EEA47_07305	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
EEA47_07310	COG1127	ABC transporter
EEA47_07320	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
EEA47_07320	COG0517	IMP dehydrogenase activity
EEA47_07330	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
EEA47_07335	COG1137	ATPase activity
EEA47_07345	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
EEA47_07350	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EEA47_07355	COG1660	Displays ATPase and GTPase activities
EEA47_07360	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EEA47_07365	COG2239	Acts as a magnesium transporter
EEA47_07370	COG0312	modulator of DNA gyrase
EEA47_07375	COG3028	Belongs to the UPF0307 family
EEA47_07380	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EEA47_07385	COG0564	pseudouridine synthase activity
EEA47_07395	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EEA47_07400	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
EEA47_07405	COG0312	modulator of DNA gyrase
EEA47_07410	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EEA47_07415	COG3164	Protein of unknown function
EEA47_07425	COG0424	maF-like protein
EEA47_07430	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
EEA47_07435	COG1792	Involved in formation and maintenance of cell shape
EEA47_07440	COG1077	Cell shape determining protein MreB Mrl
EEA47_07475	COG2165	general secretion pathway protein
EEA47_07485	COG1459	type II secretion system
EEA47_07490	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EEA47_07500	COG3267	Type II secretory pathway component ExeA
EEA47_07500	COG3409	Peptidoglycan-binding domain 1 protein
EEA47_07505	COG1450	Type ii and iii secretion system protein
EEA47_07525	COG2199	diguanylate cyclase activity
EEA47_07525	COG2200	EAL domain
EEA47_07530	COG0629	single-stranded DNA binding
EEA47_07545	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EEA47_07555	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EEA47_07565	COG0527	aspartate kinase activity
EEA47_07570	COG0646	methionine synthase
EEA47_07570	COG1410	methionine synthase
EEA47_07640	COG0175	sulfate reduction
EEA47_07645	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EEA47_07650	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
EEA47_07670	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EEA47_07675	COG0735	belongs to the Fur family
EEA47_07685	COG0166	Belongs to the GPI family
EEA47_07690	COG0432	Pfam Uncharacterised protein family UPF0047
EEA47_07695	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EEA47_07720	COG2965	DNA replication, synthesis of RNA primer
EEA47_07725	COG0360	Binds together with S18 to 16S ribosomal RNA
EEA47_07730	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EEA47_07735	COG0338	D12 class N6 adenine-specific DNA methyltransferase
EEA47_07745	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
EEA47_07750	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EEA47_07780	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
EEA47_07790	COG0678	peroxiredoxin activity
EEA47_07790	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
EEA47_07795	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EEA47_07805	COG0165	Argininosuccinate lyase
EEA47_07805	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
EEA47_07810	COG0137	argininosuccinate synthase activity
EEA47_07820	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EEA47_07830	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
EEA47_07840	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
EEA47_07845	COG0460	homoserine dehydrogenase
EEA47_07845	COG0527	aspartate kinase activity
EEA47_07850	COG0626	cystathionine gamma-synthase activity
EEA47_07855	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
EEA47_07860	COG0281	malic enzyme
EEA47_07875	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EEA47_07880	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EEA47_07900	COG2923	Belongs to the DsrF TusC family
EEA47_07905	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
EEA47_07910	COG2964	Protein conserved in bacteria
EEA47_07915	COG0545	Peptidyl-prolyl cis-trans isomerase
EEA47_07930	COG1446	asparaginase
EEA47_07935	COG1047	Peptidyl-prolyl cis-trans
EEA47_07950	COG2249	NAD(P)H dehydrogenase (quinone) activity
EEA47_07955	COG0488	(ABC) transporter
EEA47_07965	COG0429	hydrolase of the alpha beta-hydrolase fold
EEA47_07975	COG3954	Phosphoribulokinase
EEA47_07980	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EEA47_08000	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EEA47_08005	COG0512	Glutamine amidotransferase of anthranilate synthase
EEA47_08020	COG0180	Tryptophanyl-tRNA synthetase
EEA47_08025	COG0546	phosphoglycolate phosphatase activity
EEA47_08030	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EEA47_08035	COG0557	exoribonuclease II activity
EEA47_08040	COG1959	2 iron, 2 sulfur cluster binding
EEA47_08045	COG1017	nitric oxide dioxygenase activity
EEA47_08045	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EEA47_08050	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
EEA47_08060	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EEA47_08065	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
EEA47_08070	COG0330	HflC and HflK could
EEA47_08075	COG0330	HflC and HflK could
EEA47_08080	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EEA47_08090	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EEA47_08095	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EEA47_08105	COG0802	atpase or kinase
EEA47_08115	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EEA47_08180	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
EEA47_08185	COG1162	GTPase activity
EEA47_08190	COG0688	phosphatidylethanolamine metabolic process
EEA47_08195	COG0471	metal ion transport
EEA47_08195	COG3273	potassium ion transport
EEA47_08205	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
EEA47_08210	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EEA47_08215	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
EEA47_08220	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
EEA47_08225	COG1045	serine acetyltransferase
EEA47_08230	COG4942	peptidase
EEA47_08250	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
EEA47_08255	COG1053	succinate dehydrogenase
EEA47_08260	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EEA47_08265	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
EEA47_08270	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
EEA47_08285	COG1509	lysine 2,3-aminomutase activity
EEA47_08290	COG1285	pathogenesis
EEA47_08305	COG0459	protein refolding
EEA47_08315	COG0534	Mate efflux family protein
EEA47_08320	COG0205	6-phosphofructokinase activity
EEA47_08330	COG3678	ATP-independent chaperone mediated protein folding
EEA47_08335	COG0745	RESPONSE REGULATOR receiver
EEA47_08340	COG2205	protein histidine kinase activity
EEA47_08350	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
EEA47_08355	COG3030	protein affecting phage T7 exclusion by the F plasmid
EEA47_08360	COG1027	Aspartate ammonia-lyase
EEA47_08365	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
EEA47_08370	COG4232	protein-disulfide reductase activity
EEA47_08380	COG3263	regulation of cellular component size
EEA47_08390	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EEA47_08415	COG2814	Major facilitator Superfamily
EEA47_08430	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EEA47_08435	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
EEA47_08440	COG0511	ligase activity, forming carbon-carbon bonds
EEA47_08445	COG0439	Biotin carboxylase
EEA47_08455	COG2264	protein methyltransferase activity
EEA47_08460	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EEA47_08465	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
EEA47_08485	COG0582	viral genome integration into host DNA
EEA47_08495	COG0488	(ABC) transporter
EEA47_08550	COG1982	Orn Lys Arg decarboxylase major
EEA47_08555	COG0531	amino acid
EEA47_08565	COG3710	Transcriptional regulator
EEA47_08570	COG0789	Transcriptional regulator
EEA47_08585	COG0151	Belongs to the GarS family
EEA47_08600	COG1253	flavin adenine dinucleotide binding
EEA47_08605	COG3068	Protein conserved in bacteria
EEA47_08615	COG1573	uracil-dna glycosylase
EEA47_08620	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
EEA47_08625	COG2816	NAD+ diphosphatase activity
EEA47_08630	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
EEA47_08635	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EEA47_08640	COG0085	RNA polymerase activity
EEA47_08645	COG0222	ribosome binding
EEA47_08650	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EEA47_08665	COG0250	Participates in transcription elongation, termination and antitermination
EEA47_08670	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EEA47_08680	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EEA47_08715	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
EEA47_08715	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
EEA47_08720	COG0812	UDP-N-acetylmuramate dehydrogenase activity
EEA47_08730	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EEA47_08805	COG4206	TonB-dependent receptor
EEA47_08865	COG2003	Belongs to the UPF0758 family
EEA47_08955	COG5001	Diguanylate cyclase
EEA47_08975	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EEA47_08980	COG0534	Mate efflux family protein
EEA47_08985	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
EEA47_08995	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EEA47_09005	COG2937	Belongs to the GPAT DAPAT family
EEA47_09010	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
EEA47_09015	COG3161	chorismate lyase activity
EEA47_09020	COG1580	Controls the rotational direction of flagella during chemotaxis
EEA47_09025	COG0705	Rhomboid family
EEA47_09030	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EEA47_09045	COG2177	Part of the ABC transporter FtsEX involved in
EEA47_09050	COG2884	Cell division ATP-binding protein ftsE
EEA47_09055	COG0552	protein localization to endoplasmic reticulum
EEA47_09060	COG0742	ribosomal rna small subunit methyltransferase
EEA47_09070	COG2095	MarC family integral membrane protein
EEA47_09115	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EEA47_09120	COG0640	Transcriptional regulator
EEA47_09125	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
EEA47_09130	COG1280	lysine exporter protein (LysE YggA)
EEA47_09135	COG2267	carboxylic ester hydrolase activity
EEA47_09140	COG0561	phosphatase activity
EEA47_09155	COG3148	PFAM DTW domain containing protein
EEA47_09160	COG2200	EAL domain
EEA47_09160	COG2199	diguanylate cyclase activity
EEA47_09160	COG3287	FIST C domain
EEA47_09165	COG1011	Hydrolase
EEA47_09170	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
EEA47_09185	COG0019	diaminopimelate decarboxylase activity
EEA47_09195	COG1965	Belongs to the frataxin family
EEA47_09200	COG3072	Adenylate cyclase
EEA47_09205	COG0181	hydroxymethylbilane synthase activity
EEA47_09210	COG1587	Uroporphyrinogen-III synthase
EEA47_09215	COG2959	enzyme of heme biosynthesis
EEA47_09220	COG3071	HemY protein
EEA47_09265	COG0633	Ferredoxin
EEA47_09270	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
EEA47_09285	COG3118	belongs to the thioredoxin family
EEA47_09290	COG0513	Belongs to the DEAD box helicase family
EEA47_09295	COG0248	Ppx GppA phosphatase
EEA47_09305	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
EEA47_09315	COG0514	ATP-dependent DNA helicase (RecQ)
EEA47_09320	COG2962	Rard protein
EEA47_09330	COG1280	lysine exporter protein (LysE YggA)
EEA47_09335	COG0405	Gamma-glutamyltransferase
EEA47_09345	COG0210	DNA helicase
EEA47_09355	COG3220	belongs to the UPF0276 family
EEA47_09385	COG0006	proline dipeptidase activity
EEA47_09400	COG2104	thiamine diphosphate biosynthetic process
EEA47_09405	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EEA47_09425	COG2132	Multicopper oxidase
EEA47_09475	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EEA47_09480	COG1739	Uncharacterized protein family UPF0029
EEA47_09490	COG0183	Belongs to the thiolase family
EEA47_09495	COG0604	alcohol dehydrogenase
EEA47_09510	COG0425	Belongs to the sulfur carrier protein TusA family
EEA47_09520	COG2119	membrane
EEA47_09535	COG0366	Alpha amylase catalytic
EEA47_09540	COG3977	Valine--pyruvate aminotransferase
EEA47_09545	COG0071	Belongs to the small heat shock protein (HSP20) family
EEA47_09565	COG0187	DNA topoisomerase II activity
EEA47_09575	COG0592	DNA-directed DNA polymerase activity
EEA47_09580	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EEA47_09600	COG1126	abc transporter atp-binding protein
EEA47_09610	COG0594	ribonuclease P activity
EEA47_09620	COG0706	membrane insertase activity
EEA47_09630	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
EEA47_09635	COG0445	tRNA wobble uridine modification
EEA47_09640	COG0357	Ribosomal RNA small subunit methyltransferase G
EEA47_09645	COG1192	Involved in chromosome partitioning
EEA47_09650	COG1475	DNA binding
EEA47_09655	COG3312	ion transport
EEA47_09660	COG0356	it plays a direct role in the translocation of protons across the membrane
EEA47_09670	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EEA47_09675	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EEA47_09680	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EEA47_09685	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EEA47_09690	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EEA47_09695	COG0355	proton-transporting ATP synthase activity, rotational mechanism
EEA47_09705	COG0765	amino acid transport
EEA47_09715	COG2814	Major facilitator Superfamily
EEA47_09720	COG0583	DNA-binding transcription factor activity
EEA47_09730	COG0129	dihydroxy-acid dehydratase activity
EEA47_09735	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EEA47_09740	COG3978	acetolactate synthase activity
EEA47_09750	COG0606	chelatase, subunit chli
EEA47_09760	COG0204	Acyl-transferase
EEA47_09765	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EEA47_09770	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EEA47_09780	COG3084	Protein conserved in bacteria
EEA47_09790	COG4326	sporulation control protein
EEA47_09795	COG1272	protein, Hemolysin III
EEA47_09805	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EEA47_09810	COG0569	domain protein
EEA47_09815	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EEA47_09815	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EEA47_09820	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EEA47_09825	COG0242	peptide deformylase activity
EEA47_09835	COG0758	DNA mediated transformation
EEA47_09840	COG2922	Belongs to the Smg family
EEA47_09845	COG0551	DNA topoisomerase type I activity
EEA47_09850	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EEA47_09855	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EEA47_09860	COG0009	L-threonylcarbamoyladenylate synthase
EEA47_09865	COG0408	coproporphyrinogen oxidase activity
EEA47_09880	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EEA47_09915	COG0583	DNA-binding transcription factor activity
EEA47_09920	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
EEA47_09925	COG2960	long-chain fatty acid transporting porin activity
EEA47_09930	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EEA47_09935	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EEA47_09995	COG4166	transmembrane transport
EEA47_10000	COG0601	transmembrane transport
EEA47_10005	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EEA47_10045	COG1609	Transcriptional regulator
EEA47_10050	COG0583	DNA-binding transcription factor activity
EEA47_10065	COG0129	dihydroxy-acid dehydratase activity
EEA47_10070	COG3265	gluconokinase activity
EEA47_10075	COG2610	gluconate transmembrane transporter activity
EEA47_10080	COG0800	Aldolase
EEA47_10100	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EEA47_10105	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
EEA47_10115	COG1522	sequence-specific DNA binding
EEA47_10120	COG5001	Diguanylate cyclase
EEA47_10120	COG5002	protein histidine kinase activity
EEA47_10140	COG0589	response to stress
EEA47_10145	COG1528	Iron-storage protein
EEA47_10155	COG2081	HI0933 family
EEA47_10185	COG1597	lipid kinase activity
EEA47_10215	COG0628	permease
EEA47_10230	COG1322	Protein conserved in bacteria
EEA47_10235	COG2226	methyltransferase
EEA47_10240	COG3165	ubiquinone biosynthetic process from chorismate
EEA47_10245	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
EEA47_10255	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EEA47_10260	COG0805	protein transport
EEA47_10275	COG0084	hydrolase, TatD family'
EEA47_10290	COG0456	acetyltransferase
EEA47_10300	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EEA47_10300	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EEA47_10305	COG0218	Necessary for normal cell division and for the maintenance of normal septation
EEA47_10340	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
EEA47_10350	COG2204	response regulator
EEA47_10355	COG3852	Histidine kinase
EEA47_10365	COG0174	glutamine synthetase
EEA47_10370	COG1217	gtp-binding protein TYPA
EEA47_10375	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EEA47_10385	COG1295	ribonuclease BN
EEA47_10390	COG1490	D-aminoacyl-tRNA deacylase activity
EEA47_10395	COG0456	acetyltransferase
EEA47_10405	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
EEA47_10410	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
EEA47_10415	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
EEA47_10420	COG3031	protein transport across the cell outer membrane
EEA47_10430	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EEA47_10435	COG1459	type II secretion system
EEA47_10440	COG2165	general secretion pathway protein
EEA47_10445	COG2165	general secretion pathway protein
EEA47_10450	COG2165	general secretion pathway protein
EEA47_10455	COG4795	General secretion pathway protein
EEA47_10460	COG3156	type II secretion system protein K
EEA47_10465	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
EEA47_10470	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
EEA47_10480	COG1218	3'(2'),5'-bisphosphate nucleotidase
EEA47_10485	COG0494	nUDIX hydrolase
EEA47_10495	COG1040	competence protein
EEA47_10510	COG2183	response to ionizing radiation
EEA47_10520	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EEA47_10540	COG2233	PERMEase
EEA47_10545	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EEA47_10550	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EEA47_10555	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EEA47_10560	COG1758	RNA polymerase activity
EEA47_10565	COG0194	GDP metabolic process
EEA47_10585	COG0848	biopolymer transport protein
EEA47_10590	COG0811	peptide transport
EEA47_10615	COG4174	ABC transporter (Permease)
EEA47_10620	COG4239	(ABC) transporter, permease
EEA47_10625	COG0747	negative chemotaxis
EEA47_10630	COG0444	Belongs to the ABC transporter superfamily
EEA47_10635	COG4608	Belongs to the ABC transporter superfamily
EEA47_10645	COG1561	YicC-like family, N-terminal region
EEA47_10655	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
EEA47_10660	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
EEA47_10665	COG1560	Kdo2-lipid A biosynthetic process
EEA47_10670	COG1309	transcriptional regulator
EEA47_10675	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EEA47_10690	COG2003	Belongs to the UPF0758 family
EEA47_10735	COG0463	Glycosyl transferase, family 2
EEA47_10740	COG0859	PFAM glycosyl transferase family 9
EEA47_10745	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
EEA47_10750	COG3642	lipopolysaccharide core region biosynthetic process
EEA47_10770	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EEA47_10785	COG1519	Transferase
EEA47_10790	COG0859	PFAM glycosyl transferase family 9
EEA47_10795	COG1560	Kdo2-lipid A biosynthetic process
EEA47_10805	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EEA47_10840	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
EEA47_10845	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
EEA47_10855	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EEA47_10860	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
EEA47_10865	COG2089	acid synthase
EEA47_10870	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EEA47_10875	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EEA47_10880	COG1083	cytidylyl-transferase
EEA47_10885	COG2244	polysaccharide biosynthetic process
EEA47_10910	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EEA47_10915	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
EEA47_10920	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
EEA47_10925	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
EEA47_10965	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EEA47_10975	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EEA47_11000	COG0149	triose-phosphate isomerase activity
EEA47_11030	COG1494	fructose-1,6-bisphosphatase
EEA47_11040	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
EEA47_11045	COG1575	Belongs to the MenA family. Type 1 subfamily
EEA47_11050	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
EEA47_11065	COG1609	Transcriptional regulator
EEA47_11070	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EEA47_11080	COG0254	rRNA binding
EEA47_11090	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EEA47_11095	COG0088	Forms part of the polypeptide exit tunnel
EEA47_11105	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EEA47_11110	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EEA47_11115	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EEA47_11120	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
EEA47_11130	COG0255	Belongs to the universal ribosomal protein uL29 family
EEA47_11135	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EEA47_11145	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EEA47_11150	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EEA47_11160	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EEA47_11165	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
EEA47_11180	COG1841	ribosomal large subunit assembly
EEA47_11185	COG0200	Binds to the 23S rRNA
EEA47_11190	COG0201	protein transport
EEA47_11195	COG0257	Belongs to the bacterial ribosomal protein bL36 family
EEA47_11200	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EEA47_11205	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EEA47_11215	COG0202	RNA polymerase activity
EEA47_11220	COG0203	ribosomal protein L17
EEA47_11230	COG0545	Peptidyl-prolyl cis-trans isomerase
EEA47_11240	COG2153	protein acetylation
EEA47_11245	COG0513	Belongs to the DEAD box helicase family
EEA47_11260	COG1648	precorrin-2 dehydrogenase activity
EEA47_11260	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EEA47_11265	COG0175	sulfate reduction
EEA47_11270	COG2895	sulfate adenylyltransferase (ATP) activity
EEA47_11275	COG0471	metal ion transport
EEA47_11275	COG3273	potassium ion transport
EEA47_11280	COG0529	Catalyzes the synthesis of activated sulfate
EEA47_11300	COG4181	ATPase activity
EEA47_11315	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
EEA47_11325	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EEA47_11330	COG0729	surface antigen
EEA47_11335	COG2911	Protein conserved in bacteria
EEA47_11340	COG2105	PFAM AIG2 family protein
EEA47_11350	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
EEA47_11355	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
EEA47_11365	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EEA47_11370	COG0163	prenyltransferase activity
EEA47_11375	COG4143	(ABC) transporter
EEA47_11380	COG1178	ABC-type Fe3 transport system permease component
EEA47_11385	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
EEA47_11390	COG0583	DNA-binding transcription factor activity
EEA47_11395	COG1902	pentaerythritol trinitrate reductase activity
EEA47_11415	COG2358	TRAP transporter, solute receptor (TAXI family
EEA47_11440	COG0142	geranyltranstransferase activity
EEA47_11445	COG0261	This protein binds to 23S rRNA in the presence of protein L20
EEA47_11455	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EEA47_11460	COG2966	Psort location CytoplasmicMembrane, score
EEA47_11475	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EEA47_11480	COG2967	ApaG domain
EEA47_11485	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EEA47_11490	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
EEA47_11495	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EEA47_11500	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
EEA47_11505	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
EEA47_11525	COG0473	3-isopropylmalate dehydrogenase activity
EEA47_11530	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EEA47_11555	COG0583	DNA-binding transcription factor activity
EEA47_11560	COG1022	Amp-dependent synthetase and ligase
EEA47_11565	COG0028	Belongs to the TPP enzyme family
EEA47_11570	COG0440	acetolactate synthase activity
EEA47_11585	COG0469	pyruvate kinase activity
EEA47_11590	COG1349	DNA-binding transcription factor activity
EEA47_11595	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EEA47_11605	COG2376	Dihydroxyacetone kinase
EEA47_11610	COG1461	Dihydroxyacetone kinase
EEA47_11625	COG3722	fumarate hydratase activity
EEA47_11635	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
EEA47_11635	COG2213	PTS system mannitol-specific
EEA47_11660	COG0582	viral genome integration into host DNA
EEA47_11665	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EEA47_11710	COG0358	DNA primase activity
EEA47_11715	COG1610	YqeY-like protein
EEA47_11720	COG0828	Belongs to the bacterial ribosomal protein bS21 family
EEA47_11725	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
EEA47_11730	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EEA47_11735	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
EEA47_11740	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EEA47_11745	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EEA47_11750	COG1968	undecaprenyl-diphosphatase activity
EEA47_11760	COG3409	Peptidoglycan-binding domain 1 protein
EEA47_11760	COG3267	Type II secretory pathway component ExeA
EEA47_11770	COG0405	Gamma-glutamyltransferase
EEA47_11775	COG4991	sh3 domain protein
EEA47_11780	COG0306	phosphate transporter
EEA47_11785	COG1392	Phosphate transport regulator
EEA47_11790	COG3025	triphosphatase activity
EEA47_11805	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
EEA47_11810	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
EEA47_11810	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
EEA47_11815	COG1538	Outer membrane efflux protein
EEA47_11820	COG0494	nUDIX hydrolase
EEA47_11825	COG3151	Protein conserved in bacteria
EEA47_11835	COG3150	esterase
EEA47_11845	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EEA47_11850	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EEA47_11860	COG3105	Protein conserved in bacteria
EEA47_11870	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
EEA47_11885	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
EEA47_11890	COG0723	plastoquinol--plastocyanin reductase activity
EEA47_11895	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
EEA47_11900	COG2857	Cytochrome c1
EEA47_11905	COG0625	glutathione transferase activity
EEA47_11910	COG2969	positive regulation of protein catabolic process
EEA47_11915	COG2823	Periplasmic or secreted lipoprotein
EEA47_11920	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
EEA47_11935	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EEA47_11955	COG3116	cell division
EEA47_11960	COG0768	penicillin binding
EEA47_11965	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EEA47_11970	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EEA47_11975	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EEA47_11980	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EEA47_11985	COG0772	Belongs to the SEDS family
EEA47_12000	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
EEA47_12005	COG0849	cell division
EEA47_12010	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EEA47_12015	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
EEA47_12025	COG0653	protein targeting
EEA47_12030	COG0494	nUDIX hydrolase
EEA47_12040	COG0505	Belongs to the CarA family
EEA47_12045	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EEA47_12060	COG0730	response to heat
EEA47_12065	COG0583	DNA-binding transcription factor activity
EEA47_12070	COG2860	membrane
EEA47_12085	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EEA47_12095	COG0493	'glutamate synthase
EEA47_12100	COG0069	glutamate synthase activity
EEA47_12100	COG0067	glutamate synthase
EEA47_12100	COG0070	glutamate synthase
EEA47_12110	COG0067	glutamate synthase
EEA47_12110	COG0069	glutamate synthase activity
EEA47_12110	COG0070	glutamate synthase
EEA47_12115	COG1242	4 iron, 4 sulfur cluster binding
EEA47_12120	COG2203	Gaf domain
EEA47_12120	COG3706	GGDEF domain
EEA47_12120	COG4251	negative regulation of phosphorylation
EEA47_12120	COG5001	Diguanylate cyclase
EEA47_12125	COG5002	protein histidine kinase activity
EEA47_12125	COG0784	Response regulator, receiver
EEA47_12125	COG2198	Histidine kinase
EEA47_12135	COG0745	RESPONSE REGULATOR receiver
EEA47_12150	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
EEA47_12170	COG0083	homoserine kinase activity
EEA47_12175	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
EEA47_12185	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
EEA47_12190	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
EEA47_12200	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EEA47_12215	COG1115	amino acid carrier protein
EEA47_12220	COG3022	response to hydroperoxide
EEA47_12225	COG0513	Belongs to the DEAD box helicase family
EEA47_12230	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
EEA47_12240	COG0716	FMN binding
EEA47_12245	COG4974	Belongs to the 'phage' integrase family
EEA47_12250	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EEA47_12255	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EEA47_12270	COG2204	response regulator
EEA47_12280	COG0667	Aldo Keto reductase
EEA47_12305	COG0730	response to heat
EEA47_12310	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EEA47_12315	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
EEA47_12325	COG1283	sodium-dependent phosphate transmembrane transporter activity
EEA47_12330	COG0583	DNA-binding transcription factor activity
EEA47_12335	COG0640	Transcriptional regulator
EEA47_12345	COG0268	Binds directly to 16S ribosomal RNA
EEA47_12350	COG0728	peptidoglycan biosynthetic process
EEA47_12355	COG0196	riboflavin kinase activity
EEA47_12370	COG1047	Peptidyl-prolyl cis-trans
EEA47_12375	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
EEA47_12385	COG3279	Response regulator of the LytR AlgR family
EEA47_12390	COG3275	phosphorelay sensor kinase activity
EEA47_12395	COG1966	Carbon starvation protein
EEA47_12415	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
EEA47_12420	COG1472	Belongs to the glycosyl hydrolase 3 family
EEA47_12425	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EEA47_12430	COG0287	Prephenate dehydrogenase
EEA47_12430	COG1605	Chorismate mutase
EEA47_12435	COG0739	heme binding
EEA47_12445	COG0488	(ABC) transporter
EEA47_12455	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
EEA47_12460	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
EEA47_12465	COG0077	Prephenate dehydratase
EEA47_12465	COG1605	Chorismate mutase
EEA47_12470	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
EEA47_12480	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EEA47_12485	COG0564	pseudouridine synthase activity
EEA47_12495	COG0542	response to heat
EEA47_12560	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
EEA47_12565	COG0826	peptidase U32
EEA47_12570	COG2974	May be involved in recombination
EEA47_12580	COG0745	RESPONSE REGULATOR receiver
EEA47_12585	COG5002	protein histidine kinase activity
EEA47_12595	COG0248	Ppx GppA phosphatase
EEA47_12600	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
EEA47_12605	COG0573	inorganic phosphate transmembrane transporter activity
EEA47_12610	COG0581	inorganic phosphate transmembrane transporter activity
EEA47_12615	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EEA47_12620	COG0704	Plays a role in the regulation of phosphate uptake
EEA47_12630	COG3142	Participates in the control of copper homeostasis
EEA47_12635	COG0450	alkyl hydroperoxide reductase
EEA47_12640	COG0583	DNA-binding transcription factor activity
EEA47_12645	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
EEA47_12655	COG0517	IMP dehydrogenase activity
EEA47_12665	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
EEA47_12675	COG1862	Preprotein translocase
EEA47_12680	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EEA47_12685	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EEA47_12700	COG0483	inositol monophosphate 1-phosphatase activity
EEA47_12705	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
EEA47_12715	COG1104	cysteine desulfurase activity
EEA47_12720	COG0822	iron-sulfur transferase activity
EEA47_12735	COG0443	Heat shock 70 kDa protein
EEA47_12740	COG0633	Ferredoxin
EEA47_12745	COG2975	iron-sulfur cluster assembly
EEA47_12755	COG0105	UTP biosynthetic process
EEA47_12770	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
EEA47_12775	COG0124	histidyl-tRNA synthetase
EEA47_12780	COG2976	Protein conserved in bacteria
EEA47_12785	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EEA47_12790	COG1160	GTP binding
EEA47_12810	COG0516	GMP reductase activity
EEA47_12810	COG0517	IMP dehydrogenase activity
EEA47_12815	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EEA47_12815	COG0519	Catalyzes the synthesis of GMP from XMP
EEA47_12820	COG0582	viral genome integration into host DNA
EEA47_12935	COG1584	GPR1 FUN34 yaaH family protein
EEA47_12940	COG1115	amino acid carrier protein
EEA47_12955	COG2873	o-acetylhomoserine
EEA47_12960	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EEA47_12980	COG3153	acetyltransferase
EEA47_12980	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EEA47_12985	COG0583	DNA-binding transcription factor activity
EEA47_13010	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
EEA47_13015	COG2867	negative regulation of translational initiation
EEA47_13020	COG2914	Belongs to the UPF0125 (RnfH) family
EEA47_13025	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EEA47_13035	COG0497	DNA recombination
EEA47_13045	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EEA47_13050	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EEA47_13055	COG1301	dicarboxylic acid transport
EEA47_13065	COG0484	heat shock protein binding
EEA47_13095	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
EEA47_13110	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
EEA47_13115	COG0047	phosphoribosylformylglycinamidine synthase activity
EEA47_13115	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EEA47_13145	COG2195	Cleaves the N-terminal amino acid of tripeptides
EEA47_13150	COG2252	PERMEase
EEA47_13155	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
EEA47_13160	COG1073	alpha beta
EEA47_13170	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EEA47_13175	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EEA47_13180	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EEA47_13185	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EEA47_13185	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EEA47_13200	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
EEA47_13210	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
EEA47_13215	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
EEA47_13225	COG0142	geranyltranstransferase activity
EEA47_13230	COG1722	exodeoxyribonuclease VII activity
EEA47_13235	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
EEA47_13245	COG0301	tRNA thio-modification
EEA47_13245	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EEA47_13250	COG0583	DNA-binding transcription factor activity
EEA47_13260	COG2363	Small membrane protein
EEA47_13270	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EEA47_13275	COG1611	Belongs to the LOG family
EEA47_13290	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
EEA47_13290	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
EEA47_13300	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
EEA47_13305	COG1464	Belongs to the NlpA lipoprotein family
EEA47_13310	COG2011	ABC-type metal ion transport system permease component
EEA47_13315	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EEA47_13325	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
EEA47_13335	COG1263	PTS System
EEA47_13335	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EEA47_13340	COG0366	Alpha amylase catalytic
EEA47_13355	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EEA47_13360	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EEA47_13365	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
EEA47_13370	COG0321	lipoyl(octanoyl) transferase activity
EEA47_13380	COG1686	Belongs to the peptidase S11 family
EEA47_13385	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
EEA47_13390	COG0772	Belongs to the SEDS family
EEA47_13395	COG0768	penicillin binding
EEA47_13400	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EEA47_13405	COG0799	negative regulation of ribosome biogenesis
EEA47_13410	COG1466	dna polymerase III delta subunit
EEA47_13415	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
EEA47_13420	COG0495	leucyl-tRNA aminoacylation
EEA47_13425	COG2888	peptidyl-tyrosine sulfation
EEA47_13435	COG0815	Transfers the fatty acyl group on membrane lipoproteins
EEA47_13440	COG4535	Mg2 and Co2 transporter CorC
EEA47_13445	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EEA47_13450	COG1702	phosphate starvation-inducible protein PhoH
EEA47_13455	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EEA47_13465	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EEA47_13575	COG0012	GTP binding
EEA47_13580	COG0193	aminoacyl-tRNA hydrolase activity
EEA47_13585	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EEA47_13590	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
EEA47_13595	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
EEA47_13600	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
EEA47_13610	COG2890	protein-(glutamine-N5) methyltransferase activity
EEA47_13615	COG3094	Invasion gene expression up-regulator, SirB
EEA47_13620	COG2912	Transglutaminase-like superfamily
EEA47_13625	COG2877	3-deoxy-8-phosphooctulonate synthase activity
EEA47_13630	COG0737	Belongs to the 5'-nucleotidase family
EEA47_13635	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EEA47_13640	COG1187	pseudouridine synthase activity
EEA47_13645	COG2840	Smr protein MutS2
EEA47_13685	COG2217	Heavy metal translocating P-type atpase
EEA47_13685	COG2608	mercury ion transmembrane transporter activity
EEA47_13700	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
EEA47_13755	COG0784	Response regulator, receiver
EEA47_13755	COG0835	chemotaxis
EEA47_13760	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
EEA47_13765	COG1815	bacterial-type flagellum-dependent cell motility
EEA47_13770	COG1558	bacterial-type flagellum-dependent cell motility
EEA47_13780	COG1749	Flagellar hook protein flgE
EEA47_13785	COG4787	bacterial-type flagellum-dependent cell motility
EEA47_13795	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
EEA47_13800	COG1706	bacterial-type flagellum-dependent cell motility
EEA47_13805	COG1705	Flagellar rod assembly protein muramidase FlgJ
EEA47_13805	COG3951	Flagellar rod assembly protein muramidase FlgJ
EEA47_13815	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EEA47_13820	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EEA47_13830	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EEA47_13835	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EEA47_13840	COG2190	(PTS) system
EEA47_13845	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EEA47_13850	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EEA47_13860	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EEA47_13865	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
EEA47_13870	COG3115	cell septum assembly
EEA47_13875	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EEA47_13900	COG0330	HflC and HflK could
EEA47_13905	COG2194	sulfuric ester hydrolase activity
EEA47_13920	COG1192	Involved in chromosome partitioning
EEA47_13925	COG1215	transferase activity, transferring glycosyl groups
EEA47_13935	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
EEA47_13945	COG3118	belongs to the thioredoxin family
EEA47_13955	COG0300	oxidoreductase activity
EEA47_13960	COG1090	epimerase
EEA47_13990	COG0622	Phosphoesterase
EEA47_14010	COG3710	Transcriptional regulator
EEA47_14015	COG0326	Molecular chaperone. Has ATPase activity
EEA47_14025	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
EEA47_14030	COG3104	oligopeptide transport
EEA47_14035	COG0250	Participates in transcription elongation, termination and antitermination
EEA47_14040	COG0367	asparagine synthase
EEA47_14045	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EEA47_14045	COG4651	solute:proton antiporter activity
EEA47_14050	COG1940	carbohydrate kinase activity
EEA47_14050	COG1846	Transcriptional regulator
EEA47_14055	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EEA47_14065	COG1263	PTS System
EEA47_14065	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EEA47_14065	COG2190	(PTS) system
EEA47_14070	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EEA47_14075	COG0735	belongs to the Fur family
EEA47_14085	COG0716	FMN binding
EEA47_14095	COG0596	Alpha beta hydrolase
EEA47_14100	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
EEA47_14105	COG0033	Phosphoglucomutase
EEA47_14115	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EEA47_14130	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
EEA47_14135	COG1053	succinate dehydrogenase
EEA47_14140	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EEA47_14145	COG0567	Dehydrogenase, E1 component
EEA47_14150	COG0508	dehydrogenase complex catalyzes the overall conversion of
EEA47_14155	COG0045	succinate-CoA ligase (ADP-forming) activity
EEA47_14165	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EEA47_14170	COG1121	(ABC) transporter
EEA47_14175	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
EEA47_14180	COG4977	sequence-specific DNA binding
EEA47_14185	COG1918	ferrous iron import across plasma membrane
EEA47_14210	COG0018	arginyl-trna synthetase
EEA47_14220	COG3102	Protein conserved in bacteria
EEA47_14235	COG0788	formyltetrahydrofolate deformylase activity
EEA47_14240	COG1199	ATP-dependent helicase activity
EEA47_14245	COG1214	PFAM Peptidase M22, glycoprotease
EEA47_14255	COG3065	identical protein binding
EEA47_14260	COG2267	carboxylic ester hydrolase activity
EEA47_14265	COG0318	PFAM AMP-dependent synthetase and ligase
EEA47_14270	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
EEA47_14275	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
EEA47_14280	COG2894	cell division
EEA47_14285	COG0850	regulation of cytokinetic process
EEA47_14290	COG3100	YcgL domain-containing protein
EEA47_14295	COG2951	lytic endotransglycosylase activity
EEA47_14305	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EEA47_14310	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EEA47_14320	COG2226	methyltransferase
EEA47_14330	COG1028	Short-chain dehydrogenase reductase Sdr
EEA47_14340	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EEA47_14365	COG2986	histidine ammonia-lyase
EEA47_14370	COG1216	Glycosyl transferase, family 2
EEA47_14375	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EEA47_14390	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EEA47_14395	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EEA47_14430	COG0513	Belongs to the DEAD box helicase family
EEA47_14435	COG0569	domain protein
EEA47_14440	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EEA47_14455	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
EEA47_14460	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
EEA47_14465	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
EEA47_14470	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
EEA47_14495	COG0544	peptidyl-prolyl cis-trans isomerase activity
EEA47_14505	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
EEA47_14510	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
EEA47_14515	COG0776	regulation of translation
EEA47_14520	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EEA47_14525	COG1555	photosystem II stabilization
EEA47_14540	COG0232	Belongs to the dGTPase family. Type 2 subfamily
EEA47_14545	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
EEA47_14550	COG0436	Aminotransferase
EEA47_14555	COG1169	isochorismate synthase
EEA47_14560	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
EEA47_14570	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
EEA47_14590	COG2855	membrane
EEA47_14595	COG0477	Major facilitator Superfamily
EEA47_14640	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EEA47_14645	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EEA47_14660	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EEA47_14665	COG1522	sequence-specific DNA binding
EEA47_14675	COG1946	Acyl-CoA thioesterase
EEA47_14680	COG3126	Type III secretion system lipoprotein chaperone (YscW)
EEA47_14705	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EEA47_14710	COG0517	IMP dehydrogenase activity
EEA47_14710	COG0516	GMP reductase activity
EEA47_14735	COG0537	adenosine 5'-monophosphoramidase activity
EEA47_14760	COG3150	esterase
EEA47_14765	COG1252	NADH dehydrogenase
EEA47_14780	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EEA47_14790	COG4591	ABC-type transport system involved in lipoprotein release permease component
EEA47_14795	COG1136	(ABC) transporter
EEA47_14800	COG4591	ABC-type transport system involved in lipoprotein release permease component
EEA47_14810	COG0658	competence protein
EEA47_14810	COG2333	competence protein COMEC
EEA47_14815	COG1132	(ABC) transporter
EEA47_14835	COG2719	SpoVR family
EEA47_14840	COG2718	Belongs to the UPF0229 family
EEA47_14845	COG2766	serine protein kinase
EEA47_14855	COG3013	Belongs to the UPF0304 family
EEA47_14865	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EEA47_14875	COG1882	Formate acetyltransferase
EEA47_14920	COG0708	Exodeoxyribonuclease III
EEA47_14930	COG3923	Primosomal replication protein n
EEA47_14935	COG0730	response to heat
EEA47_14940	COG1199	ATP-dependent helicase activity
EEA47_14945	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
EEA47_14950	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
EEA47_14955	COG1187	pseudouridine synthase activity
EEA47_14965	COG1278	Cold shock
EEA47_14970	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
EEA47_14975	COG0542	response to heat
EEA47_14980	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
EEA47_14985	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
EEA47_14990	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
EEA47_15010	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EEA47_15015	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EEA47_15020	COG0297	glycogen (starch) synthase activity
EEA47_15040	COG3070	regulator of competence-specific genes
EEA47_15045	COG1609	Transcriptional regulator
EEA47_15050	COG3381	protein complex oligomerization
EEA47_15055	COG0745	RESPONSE REGULATOR receiver
EEA47_15060	COG1434	Gram-negative-bacterium-type cell wall biogenesis
EEA47_15065	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EEA47_15070	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
EEA47_15075	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
EEA47_15080	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
EEA47_15100	COG4067	protein conserved in archaea
EEA47_15100	COG0189	ligase activity
EEA47_15110	COG0500	methyltransferase
EEA47_15120	COG1801	Protein of unknown function DUF72
EEA47_15130	COG0217	transcriptional regulatory protein
EEA47_15135	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
EEA47_15140	COG0632	four-way junction helicase activity
EEA47_15145	COG2255	four-way junction helicase activity
EEA47_15150	COG1271	oxidase subunit
EEA47_15155	COG1294	oxidase, subunit
EEA47_15160	COG4890	Cyd operon protein YbgT
EEA47_15170	COG0824	Thioesterase
EEA47_15175	COG0811	peptide transport
EEA47_15190	COG0823	Involved in the tonB-independent uptake of proteins
EEA47_15195	COG2885	chlorophyll binding
EEA47_15200	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
EEA47_15205	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
EEA47_15215	COG3766	membrane
EEA47_15225	COG0754	glutathionylspermidine amidase activity
EEA47_15235	COG5002	protein histidine kinase activity
EEA47_15235	COG0784	Response regulator, receiver
EEA47_15250	COG1294	oxidase, subunit
EEA47_15255	COG1271	oxidase subunit
EEA47_15275	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EEA47_15280	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EEA47_15305	COG3568	Endonuclease Exonuclease Phosphatase
EEA47_15330	COG0583	DNA-binding transcription factor activity
EEA47_15340	COG0686	Belongs to the AlaDH PNT family
EEA47_15350	COG1674	ftsk spoiiie
EEA47_15360	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EEA47_15380	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EEA47_15385	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EEA47_15405	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
EEA47_15425	COG0300	oxidoreductase activity
EEA47_15440	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
EEA47_15450	COG2268	Band 7 protein
EEA47_15460	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EEA47_15465	COG2915	High frequency lysogenization protein hflD homolog
EEA47_15480	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EEA47_15490	COG1757	Na H antiporter
EEA47_15500	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
EEA47_15510	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
EEA47_15510	COG0131	Imidazoleglycerol-phosphate dehydratase
EEA47_15515	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EEA47_15520	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
EEA47_15530	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
EEA47_15530	COG0140	phosphoribosyl-ATP diphosphatase activity
EEA47_15535	COG3012	SEC-C Motif Domain Protein
EEA47_15540	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
EEA47_15545	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EEA47_15550	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EEA47_15555	COG0215	cysteine-tRNA ligase activity
EEA47_15560	COG1435	thymidine kinase activity
EEA47_15590	COG2116	formate transmembrane transporter activity
EEA47_15600	COG0390	transport system, permease component
EEA47_15605	COG4459	periplasmic nitrate reductase
EEA47_15610	COG3005	denitrification pathway
EEA47_15615	COG0243	molybdopterin cofactor binding
EEA47_15630	COG1227	inorganic diphosphatase activity
EEA47_15640	COG4172	Belongs to the ABC transporter superfamily
EEA47_15650	COG4171	peptide transport system, permease
EEA47_15665	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
EEA47_15670	COG1842	Phage shock protein A
EEA47_15680	COG1983	PspC domain protein
EEA47_15700	COG2818	Glycosylase
EEA47_15705	COG5380	lipid catabolic process
EEA47_15710	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
EEA47_15715	COG0626	cystathionine gamma-synthase activity
EEA47_15725	COG0733	neurotransmitter:sodium symporter activity
EEA47_15730	COG0564	pseudouridine synthase activity
EEA47_15740	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EEA47_15745	COG1151	hydroxylamine reductase activity
EEA47_15750	COG3604	Transcriptional regulator
EEA47_15765	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EEA47_15770	COG4136	ATPase activity
EEA47_15775	COG4135	transport system, permease component
EEA47_15780	COG4134	Bacterial extracellular solute-binding protein
EEA47_15790	COG3313	Fe-S protein
EEA47_15815	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
EEA47_15835	COG1061	Type III restriction enzyme res subunit
EEA47_15840	COG1187	pseudouridine synthase activity
EEA47_15850	COG2814	Major facilitator Superfamily
EEA47_15860	COG0702	epimerase
EEA47_15865	COG0534	Mate efflux family protein
EEA47_15885	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
EEA47_15895	COG1960	acyl-CoA dehydrogenase activity
EEA47_15900	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
EEA47_15905	COG2985	domain, Protein
EEA47_15905	COG3273	potassium ion transport
EEA47_15910	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
EEA47_15920	COG1737	Transcriptional regulator
EEA47_15925	COG0076	glutamate decarboxylase activity
EEA47_15935	COG2431	L-lysine efflux transmembrane transporter activity
EEA47_15955	COG3070	regulator of competence-specific genes
EEA47_15970	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EEA47_15970	COG4191	Histidine kinase
EEA47_15980	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
EEA47_15990	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
EEA47_15995	COG4988	ABC transporter
EEA47_16000	COG0492	ferredoxin-NADP+ reductase activity
EEA47_16025	COG0471	metal ion transport
EEA47_16030	COG2949	membrane
EEA47_16035	COG0281	malic enzyme
EEA47_16040	COG1643	Atp-dependent helicase
EEA47_16055	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
EEA47_16075	COG1024	Enoyl-CoA hydratase
EEA47_16080	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EEA47_16085	COG1960	acyl-CoA dehydrogenase activity
EEA47_16095	COG0183	Belongs to the thiolase family
EEA47_16110	COG1024	Enoyl-CoA hydratase
EEA47_16115	COG1024	Enoyl-CoA hydratase
EEA47_16125	COG1028	Short-chain dehydrogenase reductase Sdr
EEA47_16130	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
EEA47_16135	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EEA47_16140	COG1845	cytochrome c oxidase, subunit III
EEA47_16145	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
EEA47_16150	COG0109	protoheme IX farnesyltransferase activity
EEA47_16155	COG0446	pyridine nucleotide-disulphide oxidoreductase
EEA47_16155	COG1902	pentaerythritol trinitrate reductase activity
EEA47_16170	COG1012	belongs to the aldehyde dehydrogenase family
EEA47_16180	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EEA47_16210	COG1126	abc transporter atp-binding protein
EEA47_16215	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EEA47_16220	COG4215	(ABC) transporter
EEA47_16225	COG4160	amino acid transport
EEA47_16290	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EEA47_16295	COG2176	DNA-directed DNA polymerase activity
EEA47_16300	COG0517	IMP dehydrogenase activity
EEA47_16305	COG2186	Transcriptional regulator
EEA47_16310	COG2186	Transcriptional regulator
EEA47_16355	COG1917	Cupin 2, conserved barrel domain protein
EEA47_16360	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EEA47_16365	COG0800	Aldolase
EEA47_16375	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
EEA47_16380	COG1028	Short-chain dehydrogenase reductase Sdr
EEA47_16385	COG2847	Copper chaperone PCu(A)C
EEA47_16450	COG0814	amino acid
EEA47_16460	COG0243	molybdopterin cofactor binding
EEA47_16490	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EEA47_16490	COG1116	anion transmembrane transporter activity
EEA47_16495	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EEA47_16500	COG1116	anion transmembrane transporter activity
EEA47_16505	COG2146	nitrite reductase [NAD(P)H] activity
EEA47_16505	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EEA47_16550	COG0515	serine threonine protein kinase
EEA47_16550	COG2815	serine threonine protein kinase
EEA47_16585	COG0631	protein serine/threonine phosphatase activity
EEA47_16655	COG0420	3'-5' exonuclease activity
EEA47_16660	COG0419	ATPase involved in DNA repair
EEA47_16670	COG3040	lipid binding
EEA47_16680	COG1288	antiporter activity
EEA47_16690	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
EEA47_16705	COG2425	protein containing a von Willebrand factor type A (vWA) domain
EEA47_16720	COG0583	DNA-binding transcription factor activity
EEA47_16725	COG0277	FAD linked oxidase domain protein
EEA47_16740	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EEA47_16795	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EEA47_16820	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EEA47_16825	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EEA47_16835	COG2116	formate transmembrane transporter activity
EEA47_16855	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
EEA47_16895	COG3118	belongs to the thioredoxin family
EEA47_16900	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EEA47_16925	COG2271	Major facilitator Superfamily
EEA47_16930	COG3851	Histidine kinase
EEA47_16935	COG2197	response regulator
EEA47_16945	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EEA47_16950	COG0583	DNA-binding transcription factor activity
EEA47_16960	COG0243	molybdopterin cofactor binding
EEA47_16975	COG0384	phenazine biosynthesis protein PhzF
EEA47_16980	COG1794	racemase activity, acting on amino acids and derivatives
EEA47_16985	COG0446	pyridine nucleotide-disulphide oxidoreductase
EEA47_17025	COG0348	domain, Protein
EEA47_17050	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
EEA47_17075	COG0840	transmembrane signaling receptor activity
EEA47_17085	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
EEA47_17090	COG2197	response regulator
EEA47_17095	COG3850	Histidine kinase
EEA47_17100	COG2223	nitrite transmembrane transporter activity
EEA47_17105	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
EEA47_17110	COG1140	nitrate reductase beta subunit
EEA47_17115	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
EEA47_17120	COG2181	nitrate reductase activity
EEA47_17145	COG2433	Pfam Transposase IS66
EEA47_17185	COG0589	response to stress
EEA47_17190	COG4651	solute:proton antiporter activity
EEA47_17190	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EEA47_17205	COG0668	transmembrane transport
EEA47_17215	COG1968	undecaprenyl-diphosphatase activity
EEA47_17225	COG2200	EAL domain
EEA47_17225	COG2771	luxR family
EEA47_17250	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EEA47_17255	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EEA47_17270	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
EEA47_17335	COG3550	peptidyl-serine autophosphorylation
EEA47_17370	COG1328	CTP reductase activity
EEA47_17375	COG0602	queuosine metabolic process
EEA47_17380	COG0534	Mate efflux family protein
EEA47_17385	COG2207	Transcriptional regulator
EEA47_17395	COG0189	ligase activity
EEA47_17395	COG4067	protein conserved in archaea
EEA47_17405	COG3111	PFAM Bacterial OB fold (BOF) protein
EEA47_17415	COG0725	ABC transporter, periplasmic molybdate-binding protein
EEA47_17420	COG4149	molybdate abc transporter
EEA47_17425	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
EEA47_17435	COG2203	Gaf domain
EEA47_17435	COG5001	Diguanylate cyclase
EEA47_17435	COG4251	negative regulation of phosphorylation
EEA47_17435	COG3706	GGDEF domain
EEA47_17455	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
EEA47_17460	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
EEA47_17485	COG3140	Belongs to the UPF0181 family
EEA47_17635	COG0023	Translation Initiation Factor
EEA47_17645	COG1181	Belongs to the D-alanine--D-alanine ligase family
EEA47_17655	COG0045	succinate-CoA ligase (ADP-forming) activity
EEA47_17655	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EEA47_17655	COG1042	CoA-binding domain protein
EEA47_17660	COG0583	DNA-binding transcription factor activity
EEA47_17680	COG5001	Diguanylate cyclase
EEA47_17680	COG5002	protein histidine kinase activity
EEA47_17680	COG3447	MASE1 domain protein
EEA47_17685	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
EEA47_17690	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
EEA47_17695	COG1984	allophanate hydrolase subunit 2
EEA47_17705	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
EEA47_17710	COG4181	ATPase activity
EEA47_17720	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
EEA47_17725	COG5001	Diguanylate cyclase
EEA47_17725	COG3300	MHYT domain
EEA47_17760	COG4533	DNA binding
EEA47_17770	COG2050	protein possibly involved in aromatic compounds catabolism
EEA47_17785	COG2067	long-chain fatty acid transport protein
EEA47_17790	COG2267	carboxylic ester hydrolase activity
EEA47_17815	COG0737	Belongs to the 5'-nucleotidase family
EEA47_17820	COG3593	DNA synthesis involved in DNA repair
EEA47_17830	COG0583	DNA-binding transcription factor activity
EEA47_17840	COG2116	formate transmembrane transporter activity
EEA47_17845	COG2353	YceI-like domain
EEA47_17850	COG3038	cytochrome b561
EEA47_17870	COG0513	Belongs to the DEAD box helicase family
EEA47_17885	COG0840	transmembrane signaling receptor activity
EEA47_17895	COG0546	phosphoglycolate phosphatase activity
EEA47_17910	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EEA47_17915	COG2759	Belongs to the formate--tetrahydrofolate ligase family
EEA47_17920	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EEA47_17935	COG2207	Transcriptional regulator
EEA47_17940	COG1979	alcohol dehydrogenase
EEA47_17950	COG1126	abc transporter atp-binding protein
EEA47_17955	COG0765	amino acid transport
EEA47_17960	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EEA47_17965	COG0765	amino acid transport
EEA47_17970	COG2200	EAL domain
EEA47_17970	COG2199	diguanylate cyclase activity
EEA47_17970	COG2203	Gaf domain
EEA47_17985	COG1609	Transcriptional regulator
EEA47_17990	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EEA47_17990	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
EEA47_17995	COG1105	Belongs to the carbohydrate kinase PfkB family
EEA47_18000	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EEA47_18000	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EEA47_18000	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
EEA47_18030	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EEA47_18040	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EEA47_18045	COG0509	glycine decarboxylation via glycine cleavage system
EEA47_18055	COG0346	lactoylglutathione lyase activity
EEA47_18070	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EEA47_18075	COG0583	DNA-binding transcription factor activity
EEA47_18085	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EEA47_18115	COG2176	DNA-directed DNA polymerase activity
EEA47_18155	COG0242	peptide deformylase activity
EEA47_18180	COG2239	Acts as a magnesium transporter
EEA47_18200	COG0346	lactoylglutathione lyase activity
EEA47_18205	COG1902	pentaerythritol trinitrate reductase activity
EEA47_18215	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
EEA47_18215	COG2755	lipolytic protein G-D-S-L family
EEA47_18225	COG5642	Protein of unknown function (DUF2384)
EEA47_18230	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
EEA47_18265	COG2076	Multidrug Resistance protein
EEA47_18285	COG2962	Rard protein
EEA47_18300	COG0784	Response regulator, receiver
EEA47_18300	COG0835	chemotaxis
EEA47_18310	COG2197	response regulator
EEA47_18320	COG3706	GGDEF domain
EEA47_18325	COG2197	response regulator
EEA47_18330	COG5001	Diguanylate cyclase
EEA47_18330	COG3300	MHYT domain
EEA47_18335	COG0784	Response regulator, receiver
EEA47_18335	COG2205	protein histidine kinase activity
EEA47_18340	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
EEA47_18365	COG1214	PFAM Peptidase M22, glycoprotease
EEA47_18365	COG0456	acetyltransferase
EEA47_18375	COG3069	C4-dicarboxylate transmembrane transporter activity
EEA47_18400	COG3111	PFAM Bacterial OB fold (BOF) protein
EEA47_18405	COG1597	lipid kinase activity
EEA47_18410	COG0583	DNA-binding transcription factor activity
EEA47_18415	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EEA47_18445	COG0714	Associated with various cellular activities
EEA47_18450	COG0641	radical SAM
EEA47_18455	COG3119	arylsulfatase activity
EEA47_18465	COG3119	arylsulfatase activity
EEA47_18470	COG0745	RESPONSE REGULATOR receiver
EEA47_18485	COG0784	Response regulator, receiver
EEA47_18485	COG2205	protein histidine kinase activity
EEA47_18485	COG2198	Histidine kinase
EEA47_18490	COG1879	ABC-type sugar transport system periplasmic component
EEA47_18495	COG1803	Methylglyoxal synthase
EEA47_18500	COG0210	DNA helicase
EEA47_18505	COG1289	transmembrane transporter activity
EEA47_18540	COG4771	TonB-dependent receptor
EEA47_18540	COG1629	transport
EEA47_18550	COG0789	Transcriptional regulator
EEA47_18555	COG4604	ABC transporter, ATP-binding protein
EEA47_18560	COG4605	iron ion homeostasis
EEA47_18565	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EEA47_18570	COG4607	ABC-type enterochelin transport system periplasmic component
EEA47_18580	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
EEA47_18595	COG1609	Transcriptional regulator
EEA47_18600	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EEA47_18605	COG1879	ABC-type sugar transport system periplasmic component
EEA47_18610	COG1172	Belongs to the binding-protein-dependent transport system permease family
EEA47_18615	COG1129	ABC transporter
EEA47_18620	COG1869	D-ribose catabolic process
EEA47_18625	COG5001	Diguanylate cyclase
EEA47_18680	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EEA47_18690	COG2205	protein histidine kinase activity
EEA47_18690	COG0784	Response regulator, receiver
EEA47_18705	COG0330	HflC and HflK could
EEA47_18720	COG0517	IMP dehydrogenase activity
EEA47_18720	COG4175	Glycine betaine
EEA47_18725	COG4176	ABC-type proline glycine betaine transport system permease component
EEA47_18740	COG1012	belongs to the aldehyde dehydrogenase family
EEA47_18745	COG1309	transcriptional regulator
EEA47_18755	COG1028	Short-chain dehydrogenase reductase Sdr
EEA47_18770	COG1024	Enoyl-CoA hydratase
EEA47_18775	COG1960	acyl-CoA dehydrogenase activity
EEA47_18785	COG0183	Belongs to the thiolase family
EEA47_18795	COG1960	acyl-CoA dehydrogenase activity
EEA47_18800	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EEA47_18810	COG4770	biotin carboxylase activity
EEA47_18825	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
EEA47_18825	COG3264	Mechanosensitive ion channel
EEA47_18835	COG0110	maltose O-acetyltransferase activity
EEA47_18840	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EEA47_18845	COG1271	oxidase subunit
EEA47_18850	COG1294	oxidase, subunit
EEA47_18865	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EEA47_18875	COG3527	Alpha-acetolactate decarboxylase
EEA47_18890	COG0500	methyltransferase
EEA47_18920	COG1022	Amp-dependent synthetase and ligase
EEA47_18950	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EEA47_18955	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EEA47_18955	COG1263	PTS System
EEA47_18960	COG1486	melibiose metabolic process
EEA47_18965	COG2188	Transcriptional regulator
EEA47_18970	COG1320	monovalent cation:proton antiporter activity
EEA47_18975	COG2212	antiporter activity
EEA47_18980	COG1863	multisubunit Na H antiporter MnhE subunit
EEA47_18985	COG0651	ATP synthesis coupled electron transport
EEA47_18990	COG1006	Multisubunit Na H antiporter MnhC subunit
EEA47_18995	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EEA47_18995	COG2111	Na H antiporter
EEA47_19005	COG0589	response to stress
EEA47_19010	COG4221	oxidoreductase activity
EEA47_19015	COG0583	DNA-binding transcription factor activity
EEA47_19025	COG2814	Major facilitator Superfamily
EEA47_19090	COG1522	sequence-specific DNA binding
EEA47_19125	COG0515	serine threonine protein kinase
EEA47_19150	COG3501	Rhs element vgr protein
EEA47_19190	COG0739	heme binding
EEA47_19205	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EEA47_19255	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
EEA47_19265	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
EEA47_19265	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
EEA47_19280	COG4989	oxidoreductase activity
EEA47_19295	COG0038	chloride channel
EEA47_19330	COG2897	thiosulfate sulfurtransferase activity
EEA47_19350	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EEA47_19355	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EEA47_19360	COG0840	transmembrane signaling receptor activity
EEA47_19365	COG2814	Major facilitator Superfamily
EEA47_19370	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EEA47_19385	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EEA47_19395	COG0840	transmembrane signaling receptor activity
EEA47_19415	COG2195	Cleaves the N-terminal amino acid of tripeptides
EEA47_19430	COG2197	response regulator
EEA47_19435	COG3850	Histidine kinase
EEA47_19440	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
EEA47_19450	COG0243	molybdopterin cofactor binding
EEA47_19460	COG3005	denitrification pathway
EEA47_19470	COG3243	poly(R)-hydroxyalkanoic acid synthase
EEA47_19480	COG0183	Belongs to the thiolase family
EEA47_19490	COG1280	lysine exporter protein (LysE YggA)
EEA47_19500	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EEA47_19505	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EEA47_19560	COG1846	Transcriptional regulator
EEA47_19565	COG0784	Response regulator, receiver
EEA47_19565	COG2205	protein histidine kinase activity
EEA47_19570	COG1879	ABC-type sugar transport system periplasmic component
EEA47_19580	COG2827	Endonuclease containing a URI domain
EEA47_19585	COG3132	Protein of unknown function, DUF480
EEA47_19605	COG2205	protein histidine kinase activity
EEA47_19605	COG5002	protein histidine kinase activity
EEA47_19605	COG0784	Response regulator, receiver
EEA47_19625	COG0583	DNA-binding transcription factor activity
EEA47_19640	COG0531	amino acid
EEA47_19655	COG2205	protein histidine kinase activity
EEA47_19660	COG0745	RESPONSE REGULATOR receiver
EEA47_19685	COG1566	PFAM secretion protein HlyD family protein
EEA47_19690	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
EEA47_19695	COG2239	Acts as a magnesium transporter
EEA47_19700	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
EEA47_19705	COG0402	S-adenosylhomocysteine deaminase activity
EEA47_19710	COG1418	mRNA catabolic process
EEA47_19725	COG2814	Major facilitator Superfamily
EEA47_19735	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EEA47_19755	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EEA47_19770	COG0745	RESPONSE REGULATOR receiver
EEA47_19775	COG2205	protein histidine kinase activity
EEA47_19785	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
EEA47_19790	COG2194	sulfuric ester hydrolase activity
EEA47_19810	COG4667	esterase of the alpha-beta hydrolase superfamily
EEA47_19815	COG1741	Belongs to the pirin family
EEA47_19820	COG1278	Cold shock
EEA47_19835	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
EEA47_19840	COG0678	peroxiredoxin activity
EEA47_19840	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
EEA47_19850	COG1686	Belongs to the peptidase S11 family
EEA47_19860	COG0625	glutathione transferase activity
EEA47_19870	COG1621	beta-fructofuranosidase activity
EEA47_19875	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EEA47_19880	COG1263	PTS System
EEA47_19880	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EEA47_19900	COG4771	TonB-dependent receptor
EEA47_19905	COG0583	DNA-binding transcription factor activity
EEA47_19915	COG1404	Belongs to the peptidase S8 family
EEA47_19920	COG1028	Short-chain dehydrogenase reductase Sdr
EEA47_19935	COG3746	phosphate-selective porin O and P
EEA47_19950	COG0300	oxidoreductase activity
EEA47_19955	COG0583	DNA-binding transcription factor activity
EEA47_19960	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EEA47_19960	COG2207	Transcriptional regulator
EEA47_19965	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EEA47_19995	COG0513	Belongs to the DEAD box helicase family
EEA47_20005	COG0583	DNA-binding transcription factor activity
EEA47_20020	COG1902	pentaerythritol trinitrate reductase activity
EEA47_20025	COG1063	alcohol dehydrogenase
EEA47_20035	COG1028	Short-chain dehydrogenase reductase Sdr
EEA47_20045	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EEA47_20050	COG0006	proline dipeptidase activity
EEA47_20055	COG3608	succinylglutamate desuccinylase aspartoacylase
EEA47_20060	COG1522	sequence-specific DNA binding
EEA47_20065	COG1012	belongs to the aldehyde dehydrogenase family
EEA47_20070	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EEA47_20075	COG3122	Protein conserved in bacteria
EEA47_20090	COG0583	DNA-binding transcription factor activity
EEA47_20095	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EEA47_20100	COG0252	asparaginase activity
EEA47_20105	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
EEA47_20120	COG2197	response regulator
EEA47_20125	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EEA47_20150	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EEA47_20180	COG3842	ATPase activity
EEA47_20200	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EEA47_20230	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EEA47_20270	COG0583	DNA-binding transcription factor activity
EEA47_20280	COG4948	Mandelate Racemase Muconate Lactonizing
EEA47_20315	COG1342	Belongs to the UPF0251 family
EEA47_20325	COG4176	ABC-type proline glycine betaine transport system permease component
EEA47_20330	COG3448	diguanylate cyclase activity
EEA47_20330	COG4175	Glycine betaine
EEA47_20335	COG3015	lipoprotein NlpE involved in copper resistance
EEA47_20340	COG3713	MltA-interacting MipA family protein
EEA47_20355	COG0583	DNA-binding transcription factor activity
EEA47_20380	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EEA47_20390	COG1335	isochorismatase
EEA47_20405	COG1349	DNA-binding transcription factor activity
EEA47_20410	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EEA47_20410	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EEA47_20415	COG2070	2-Nitropropane dioxygenase
EEA47_20420	COG0531	amino acid
EEA47_20425	COG4302	ethanolamine ammonia-lyase activity
EEA47_20430	COG4303	Ethanolamine ammonia lyase large subunit
EEA47_20440	COG1309	transcriptional regulator
EEA47_20460	COG1280	lysine exporter protein (LysE YggA)
EEA47_20470	COG0459	protein refolding
EEA47_20475	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EEA47_20485	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EEA47_20500	COG1304	FMN binding
EEA47_20525	COG1256	bacterial-type flagellum assembly
EEA47_20525	COG4786	Flagellar basal body rod
EEA47_20535	COG1706	bacterial-type flagellum-dependent cell motility
EEA47_20540	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
EEA47_20545	COG4786	Flagellar basal body rod
EEA47_20550	COG4787	bacterial-type flagellum-dependent cell motility
EEA47_20565	COG1558	bacterial-type flagellum-dependent cell motility
EEA47_20570	COG1815	bacterial-type flagellum-dependent cell motility
EEA47_20590	COG0741	lytic transglycosylase activity
EEA47_20595	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EEA47_20615	COG1760	l-serine dehydratase
EEA47_20630	COG0583	DNA-binding transcription factor activity
EEA47_20640	COG2866	Carboxypeptidase
EEA47_20645	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EEA47_20655	COG2990	Protein conserved in bacteria
EEA47_20680	COG3842	ATPase activity
EEA47_20685	COG1840	ABC-type Fe3 transport system, periplasmic component
EEA47_20695	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EEA47_20705	COG1609	Transcriptional regulator
EEA47_20735	COG3240	lipase activity
EEA47_20740	COG1309	transcriptional regulator
EEA47_20755	COG0577	efflux transmembrane transporter activity
EEA47_20755	COG1136	(ABC) transporter
EEA47_20760	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EEA47_20765	COG2067	long-chain fatty acid transport protein
EEA47_20775	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
EEA47_20790	COG1011	Hydrolase
EEA47_20830	COG0110	maltose O-acetyltransferase activity
EEA47_20835	COG1765	OsmC-like protein
EEA47_20840	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EEA47_20840	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EEA47_20855	COG3046	protein related to deoxyribodipyrimidine photolyase
EEA47_20860	COG0415	Belongs to the DNA photolyase family
EEA47_20865	COG3706	GGDEF domain
EEA47_20895	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EEA47_20915	COG3033	Beta-eliminating lyase
EEA47_20925	COG1271	oxidase subunit
EEA47_20930	COG1294	oxidase, subunit
EEA47_20945	COG0579	oxidoreductase
EEA47_20970	COG3706	GGDEF domain
EEA47_21000	COG0583	DNA-binding transcription factor activity
EEA47_21025	COG0189	ligase activity
EEA47_21030	COG0189	ligase activity
EEA47_21030	COG4067	protein conserved in archaea
EEA47_21040	COG1166	arginine decarboxylase activity
EEA47_21050	COG2814	Major facilitator Superfamily
EEA47_21055	COG1770	oligopeptidase
EEA47_21070	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EEA47_21075	COG1121	(ABC) transporter
EEA47_21080	COG0803	Belongs to the bacterial solute-binding protein 9 family
EEA47_21125	COG0848	biopolymer transport protein
EEA47_21130	COG0811	peptide transport
EEA47_21135	COG0811	peptide transport
EEA47_21155	COG0745	RESPONSE REGULATOR receiver
EEA47_21160	COG0584	glycerophosphoryl diester phosphodiesterase
EEA47_21170	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EEA47_21240	COG0312	modulator of DNA gyrase
EEA47_21245	COG0312	modulator of DNA gyrase
EEA47_21250	COG0351	phosphomethylpyrimidine kinase
EEA47_21255	COG1116	anion transmembrane transporter activity
EEA47_21260	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EEA47_21265	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EEA47_21270	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EEA47_21280	COG0352	thiamine-phosphate diphosphorylase activity
EEA47_21290	COG0243	molybdopterin cofactor binding
EEA47_21295	COG3005	denitrification pathway
EEA47_21300	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EEA47_21305	COG1028	Short-chain dehydrogenase reductase Sdr
EEA47_21320	COG0456	acetyltransferase
EEA47_21340	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EEA47_21345	COG1929	Belongs to the glycerate kinase type-1 family
EEA47_21350	COG2610	gluconate transmembrane transporter activity
EEA47_21355	COG3835	regulator
EEA47_21415	COG3047	cAMP biosynthetic process
EEA47_21420	COG1357	PFAM Pentapeptide repeats (8 copies)
EEA47_21450	COG2375	cellular response to nickel ion
EEA47_21455	COG0583	DNA-binding transcription factor activity
EEA47_21460	COG2162	N-hydroxyarylamine O-acetyltransferase activity
EEA47_21465	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
EEA47_21480	COG2199	diguanylate cyclase activity
EEA47_21490	COG0561	phosphatase activity
EEA47_21495	COG0583	DNA-binding transcription factor activity
EEA47_21510	COG0564	pseudouridine synthase activity
EEA47_21515	COG0534	Mate efflux family protein
EEA47_21530	COG3123	guanosine phosphorylase activity
EEA47_21545	COG0596	Alpha beta hydrolase
EEA47_21570	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EEA47_21580	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EEA47_21585	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EEA47_21585	COG2169	Transcriptional regulator
EEA47_21595	COG2259	Doxx family
EEA47_21600	COG1741	Belongs to the pirin family
EEA47_21620	COG0363	glucosamine-6-phosphate deaminase activity
EEA47_21630	COG0786	glutamate:sodium symporter activity
EEA47_21635	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EEA47_21640	COG1131	(ABC) transporter
EEA47_21650	COG0786	glutamate:sodium symporter activity
EEA47_21675	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EEA47_21685	COG3279	Response regulator of the LytR AlgR family
EEA47_21690	COG3275	phosphorelay sensor kinase activity
EEA47_21710	COG1136	(ABC) transporter
EEA47_21720	COG0772	Belongs to the SEDS family
EEA47_21745	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
EEA47_21745	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EEA47_21755	COG0444	Belongs to the ABC transporter superfamily
EEA47_21760	COG4608	Belongs to the ABC transporter superfamily
EEA47_21785	COG1444	tRNA N-acetyltransferase activity
EEA47_21810	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
EEA47_21815	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EEA47_21815	COG1263	PTS System
EEA47_21820	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
EEA47_21840	COG4166	transmembrane transport
EEA47_21885	COG0259	pyridoxamine-phosphate oxidase activity
EEA47_21910	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EEA47_21960	COG0513	Belongs to the DEAD box helicase family
EEA47_21965	COG2258	MOSC domain
EEA47_22025	COG3634	alkyl hydroperoxide reductase activity
EEA47_22035	COG1846	Transcriptional regulator
EEA47_22040	COG1764	response to oxidative stress
EEA47_22075	COG0577	efflux transmembrane transporter activity
EEA47_22080	COG1136	(ABC) transporter
EEA47_22100	COG0826	peptidase U32
EEA47_22130	COG1653	transport
EEA47_22135	COG0019	diaminopimelate decarboxylase activity
EEA47_22140	COG4264	IucA IucC family
EEA47_22145	COG2814	Major facilitator Superfamily
EEA47_22165	COG4772	TonB-dependent receptor
EEA47_22170	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
EEA47_22175	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EEA47_22180	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EEA47_22185	COG1120	ATPase activity
EEA47_22190	COG0840	transmembrane signaling receptor activity
EEA47_22195	COG0612	Peptidase, M16
EEA47_22205	COG0739	heme binding
EEA47_22220	COG2814	Major facilitator Superfamily
EEA47_22230	COG1609	Transcriptional regulator
EEA47_22235	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EEA47_22250	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
EEA47_22250	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
EEA47_22260	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
EEA47_22265	COG1609	Transcriptional regulator
EEA47_22275	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
EEA47_22315	COG1760	l-serine dehydratase
EEA47_22325	COG4580	involved in the transport of maltose and maltodextrins
EEA47_22345	COG2356	endonuclease I
EEA47_22365	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
EEA47_22370	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
EEA47_22375	COG1162	GTPase activity
EEA47_22380	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EEA47_22380	COG1263	PTS System
EEA47_22385	COG1999	signal sequence binding
EEA47_22400	COG2909	trisaccharide binding
EEA47_22405	COG0058	SHG alpha-glucan phosphorylase activity
EEA47_22410	COG1640	4-alpha-glucanotransferase
EEA47_22415	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
EEA47_22420	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EEA47_22425	COG0366	Alpha amylase catalytic
EEA47_22440	COG3366	ferrous iron transmembrane transporter activity
EEA47_22445	COG0700	Nucleoside recognition
EEA47_22450	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EEA47_22455	COG3339	Conserved Protein
EEA47_22460	COG1301	dicarboxylic acid transport
EEA47_22470	COG0583	DNA-binding transcription factor activity
EEA47_22490	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EEA47_22495	COG1596	polysaccharide export
EEA47_22510	COG2095	MarC family integral membrane protein
EEA47_22515	COG4667	esterase of the alpha-beta hydrolase superfamily
EEA47_22520	COG3397	chitin binding
EEA47_22525	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
EEA47_22530	COG0415	Belongs to the DNA photolyase family
EEA47_22540	COG1054	Belongs to the UPF0176 family
EEA47_22550	COG1686	Belongs to the peptidase S11 family
EEA47_22575	COG0583	DNA-binding transcription factor activity
EEA47_22580	COG4628	conserved protein (DUF2132)
EEA47_22600	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
EEA47_22605	COG0628	permease
EEA47_22650	COG2814	Major facilitator Superfamily
EEA47_22660	COG0454	-acetyltransferase
EEA47_22670	COG0745	RESPONSE REGULATOR receiver
EEA47_22675	COG2205	protein histidine kinase activity
EEA47_22690	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EEA47_22695	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EEA47_22700	COG1882	Formate acetyltransferase
EEA47_22735	COG1360	Flagellar Motor Protein
EEA47_22740	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
EEA47_22745	COG1191	sigma factor activity
EEA47_22750	COG1580	Controls the rotational direction of flagella during chemotaxis
EEA47_22765	COG1516	flagellar protein fliS
EEA47_22770	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
EEA47_22780	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EEA47_22795	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EEA47_22805	COG1987	bacterial-type flagellum assembly
EEA47_22845	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EEA47_22905	COG0346	lactoylglutathione lyase activity
EEA47_22930	COG0745	RESPONSE REGULATOR receiver
EEA47_22955	COG3300	MHYT domain
EEA47_22955	COG5001	Diguanylate cyclase
EEA47_22960	COG0156	8-amino-7-oxononanoate synthase activity
EEA47_22965	COG1063	alcohol dehydrogenase
EEA47_23000	COG0668	transmembrane transport
EEA47_23010	COG1304	FMN binding
EEA47_23015	COG1620	l-lactate permease
EEA47_23020	COG0583	DNA-binding transcription factor activity
EEA47_23025	COG1505	serine-type exopeptidase activity
EEA47_23030	COG4172	Belongs to the ABC transporter superfamily
EEA47_23040	COG1067	ATP-dependent peptidase activity
EEA47_23045	COG0840	transmembrane signaling receptor activity
EEA47_23050	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
EEA47_23070	COG1247	-acetyltransferase
EEA47_23075	COG0437	4 iron, 4 sulfur cluster binding
EEA47_23080	COG0348	domain, Protein
EEA47_23100	COG1122	ATPase activity
EEA47_23105	COG4720	Psort location CytoplasmicMembrane, score
EEA47_23110	COG1566	PFAM secretion protein HlyD family protein
EEA47_23135	COG0813	purine-nucleoside phosphorylase activity
EEA47_23140	COG3272	Protein of unknown function (DUF1722)
EEA47_23145	COG0789	Transcriptional regulator
EEA47_23150	COG0415	Belongs to the DNA photolyase family
EEA47_23155	COG1376	ErfK ybiS ycfS ynhG family protein
EEA47_23155	COG1388	LysM domain
EEA47_23165	COG0513	Belongs to the DEAD box helicase family
EEA47_23170	COG1770	oligopeptidase
EEA47_23175	COG4771	TonB-dependent receptor
EEA47_23205	COG0573	inorganic phosphate transmembrane transporter activity
EEA47_23210	COG0581	inorganic phosphate transmembrane transporter activity
EEA47_23215	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EEA47_23230	COG2304	oxidoreductase activity
EEA47_23235	COG2304	oxidoreductase activity
EEA47_23250	COG0714	Associated with various cellular activities
EEA47_23265	COG2197	response regulator
EEA47_23300	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
EEA47_23305	COG1120	ATPase activity
EEA47_23310	COG4774	siderophore transport
EEA47_23315	COG1132	(ABC) transporter
EEA47_23320	COG2205	protein histidine kinase activity
EEA47_23325	COG0745	RESPONSE REGULATOR receiver
EEA47_23330	COG0569	domain protein
EEA47_23335	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EEA47_23340	COG0583	DNA-binding transcription factor activity
EEA47_23355	COG1012	belongs to the aldehyde dehydrogenase family
EEA47_23360	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EEA47_23365	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EEA47_23375	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
EEA47_23380	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EEA47_23410	COG2084	Dehydrogenase
EEA47_23415	COG0753	catalase activity
EEA47_23425	COG2130	NADP-dependent
EEA47_23430	COG1309	transcriptional regulator
EEA47_23435	COG3097	Belongs to the UPF0267 family
EEA47_23475	COG3206	protein involved in exopolysaccharide biosynthesis
EEA47_23475	COG0489	protein tyrosine kinase activity
EEA47_23490	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EEA47_23495	COG3842	ATPase activity
EEA47_23505	COG1175	transmembrane transport
EEA47_23510	COG3833	ABC-type maltose transport systems, permease component
EEA47_23540	COG2354	Protein conserved in bacteria
EEA47_23545	COG0418	dihydroorotase activity
EEA47_23555	COG0401	homolog of Blt101
EEA47_23560	COG0633	Ferredoxin
EEA47_23560	COG0633	Ferredoxin
EEA47_23560	COG3217	Mosc domain protein beta barrel domain protein
EEA47_23560	COG3217	Mosc domain protein beta barrel domain protein
EEA47_23570	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EEA47_23615	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
EEA47_23620	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EEA47_23630	COG0848	biopolymer transport protein
EEA47_23635	COG0811	peptide transport
EEA47_23640	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
EEA47_23650	COG3721	Heme iron utilization protein
EEA47_23655	COG0748	coenzyme F420 binding
EEA47_23665	COG0784	Response regulator, receiver
EEA47_23665	COG0835	chemotaxis
EEA47_23670	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EEA47_23675	COG0534	Mate efflux family protein
EEA47_23680	COG0444	Belongs to the ABC transporter superfamily
EEA47_23685	COG4608	Belongs to the ABC transporter superfamily
EEA47_23690	COG0747	negative chemotaxis
EEA47_23700	COG1349	DNA-binding transcription factor activity
EEA47_23705	COG2084	Dehydrogenase
EEA47_23710	COG3395	kinase activity
EEA47_23715	COG0235	Class ii aldolase
EEA47_23720	COG3622	Belongs to the hyi family
EEA47_23725	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EEA47_23730	COG2610	gluconate transmembrane transporter activity
EEA47_23755	COG0583	DNA-binding transcription factor activity
EEA47_23760	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EEA47_23770	COG4934	collagen metabolic process
EEA47_23780	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EEA47_23785	COG0789	Transcriptional regulator
EEA47_23790	COG0366	Alpha amylase catalytic
EEA47_23810	COG2249	NAD(P)H dehydrogenase (quinone) activity
EEA47_23815	COG0589	response to stress
EEA47_23820	COG0488	(ABC) transporter
EEA47_23825	COG1505	serine-type exopeptidase activity
EEA47_23835	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EEA47_23845	COG2067	long-chain fatty acid transport protein
EEA47_23855	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EEA47_23880	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EEA47_23900	COG3383	formate dehydrogenase (NAD+) activity
EEA47_23910	COG0842	Transport permease protein
EEA47_23915	COG1131	(ABC) transporter
EEA47_23935	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
EEA47_23945	COG4145	pantothenate transmembrane transporter activity
EEA47_23950	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EEA47_23955	COG0800	Aldolase
EEA47_23970	COG2706	6-phosphogluconolactonase activity
EEA47_23975	COG0251	oxidation-reduction process
EEA47_23985	COG1881	PFAM PEBP family protein
EEA47_23995	COG0798	PFAM Bile acid sodium symporter
EEA47_24010	COG1733	regulation of RNA biosynthetic process
EEA47_24035	COG4989	oxidoreductase activity
EEA47_24060	COG0814	amino acid
EEA47_24075	COG3314	Sporulation integral membrane protein YlbJ
EEA47_24100	COG0739	heme binding
EEA47_24105	COG5001	Diguanylate cyclase
EEA47_24110	COG0583	DNA-binding transcription factor activity
EEA47_24115	COG2814	Major facilitator Superfamily
EEA47_24135	COG0697	spore germination
EEA47_24150	COG0179	Fumarylacetoacetate (FAA) hydrolase
EEA47_24170	COG1280	lysine exporter protein (LysE YggA)
EEA47_24180	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EEA47_24185	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
EEA47_24190	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EEA47_24195	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
EEA47_24200	COG1845	cytochrome c oxidase, subunit III
EEA47_24220	COG1612	heme a metabolic process
EEA47_24225	COG0109	protoheme IX farnesyltransferase activity
EEA47_24230	COG0545	Peptidyl-prolyl cis-trans isomerase
EEA47_24260	COG1278	Cold shock
EEA47_24265	COG3036	rescue of stalled ribosome
EEA47_24270	COG2199	diguanylate cyclase activity
EEA47_24285	COG1132	(ABC) transporter
EEA47_24295	COG1538	Outer membrane efflux protein
EEA47_24300	COG2205	protein histidine kinase activity
EEA47_24300	COG0784	Response regulator, receiver
EEA47_24325	COG0840	transmembrane signaling receptor activity
EEA47_24330	COG0783	Belongs to the Dps family
EEA47_24340	COG2133	pyrroloquinoline quinone binding
EEA47_24345	COG1454	alcohol dehydrogenase
EEA47_24350	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
EEA47_24370	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EEA47_24375	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EEA47_24380	COG3186	Phenylalanine-4-hydroxylase
EEA47_24405	COG3530	Putative quorum-sensing-regulated virulence factor
EEA47_24420	COG2186	Transcriptional regulator
EEA47_24435	COG1279	arginine transmembrane transporter activity
EEA47_24450	COG0730	response to heat
EEA47_24460	COG0513	Belongs to the DEAD box helicase family
EEA47_24465	COG4628	conserved protein (DUF2132)
EEA47_24475	COG0133	tryptophan synthase activity
EEA47_24485	COG1278	Cold shock
EEA47_24495	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
EEA47_24505	COG0523	cobalamin synthesis protein
EEA47_24510	COG0513	Belongs to the DEAD box helicase family
EEA47_24530	COG2200	EAL domain
EEA47_24535	COG1119	ATPase activity
EEA47_24625	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
EEA47_24630	COG0513	Belongs to the DEAD box helicase family
EEA47_24645	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EEA47_24655	COG1073	alpha beta
EEA47_24660	COG1073	alpha beta
EEA47_24675	COG0730	response to heat
EEA47_24690	COG0735	belongs to the Fur family
EEA47_24695	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
EEA47_24705	COG0523	cobalamin synthesis protein
EEA47_24710	COG2988	succinylglutamate desuccinylase activity
EEA47_24715	COG0739	heme binding
EEA47_24725	COG0523	cobalamin synthesis protein
EEA47_24745	COG2095	MarC family integral membrane protein