locus-tag	class	description
K6806_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
K6806_00010	COG0592	DNA-directed DNA polymerase activity
K6806_00020	COG0187	DNA topoisomerase II activity
K6806_00030	COG0071	Belongs to the small heat shock protein (HSP20) family
K6806_00035	COG3977	Valine--pyruvate aminotransferase
K6806_00040	COG0366	Alpha amylase catalytic
K6806_00055	COG2119	membrane
K6806_00065	COG0425	Belongs to the sulfur carrier protein TusA family
K6806_00080	COG0604	alcohol dehydrogenase
K6806_00085	COG0183	Belongs to the thiolase family
K6806_00095	COG1739	Uncharacterized protein family UPF0029
K6806_00100	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
K6806_00140	COG0583	DNA-binding transcription factor activity
K6806_00145	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
K6806_00150	COG2960	long-chain fatty acid transporting porin activity
K6806_00155	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
K6806_00160	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
K6806_00215	COG4166	transmembrane transport
K6806_00220	COG0601	transmembrane transport
K6806_00225	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
K6806_00260	COG1609	Transcriptional regulator
K6806_00265	COG0583	DNA-binding transcription factor activity
K6806_00280	COG0129	dihydroxy-acid dehydratase activity
K6806_00285	COG3265	gluconokinase activity
K6806_00290	COG2610	gluconate transmembrane transporter activity
K6806_00295	COG0800	Aldolase
K6806_00300	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
K6806_00305	COG0583	DNA-binding transcription factor activity
K6806_00310	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
K6806_00315	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
K6806_00325	COG1522	sequence-specific DNA binding
K6806_00330	COG5001	Diguanylate cyclase
K6806_00330	COG5002	protein histidine kinase activity
K6806_00335	COG0742	ribosomal rna small subunit methyltransferase
K6806_00350	COG0589	response to stress
K6806_00355	COG1528	Iron-storage protein
K6806_00365	COG2081	HI0933 family
K6806_00395	COG1597	lipid kinase activity
K6806_00425	COG0628	permease
K6806_00440	COG1322	Protein conserved in bacteria
K6806_00445	COG2226	methyltransferase
K6806_00450	COG3165	ubiquinone biosynthetic process from chorismate
K6806_00455	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
K6806_00465	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
K6806_00470	COG0805	protein transport
K6806_00475	COG0084	hydrolase, TatD family'
K6806_00485	COG0456	acetyltransferase
K6806_00490	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
K6806_00490	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
K6806_00495	COG0218	Necessary for normal cell division and for the maintenance of normal septation
K6806_00525	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
K6806_00535	COG2204	response regulator
K6806_00540	COG3852	Histidine kinase
K6806_00550	COG0174	glutamine synthetase
K6806_00555	COG1217	gtp-binding protein TYPA
K6806_00560	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
K6806_00570	COG1295	ribonuclease BN
K6806_00575	COG1490	D-aminoacyl-tRNA deacylase activity
K6806_00580	COG0456	acetyltransferase
K6806_00590	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
K6806_00595	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
K6806_00600	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
K6806_00605	COG3031	protein transport across the cell outer membrane
K6806_00615	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
K6806_00620	COG1459	type II secretion system
K6806_00625	COG2165	general secretion pathway protein
K6806_00630	COG2165	general secretion pathway protein
K6806_00635	COG2165	general secretion pathway protein
K6806_00640	COG4795	General secretion pathway protein
K6806_00645	COG3156	type II secretion system protein K
K6806_00650	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
K6806_00655	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
K6806_00665	COG1218	3'(2'),5'-bisphosphate nucleotidase
K6806_00670	COG0494	nUDIX hydrolase
K6806_00680	COG1040	competence protein
K6806_00695	COG2183	response to ionizing radiation
K6806_00705	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
K6806_00725	COG2233	PERMEase
K6806_00730	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
K6806_00735	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
K6806_00740	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
K6806_00745	COG1758	RNA polymerase activity
K6806_00750	COG0194	GDP metabolic process
K6806_00765	COG0848	biopolymer transport protein
K6806_00770	COG0811	peptide transport
K6806_00790	COG4174	ABC transporter (Permease)
K6806_00795	COG4239	(ABC) transporter, permease
K6806_00800	COG0747	negative chemotaxis
K6806_00805	COG0444	Belongs to the ABC transporter superfamily
K6806_00810	COG4608	Belongs to the ABC transporter superfamily
K6806_00820	COG1561	YicC-like family, N-terminal region
K6806_00825	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
K6806_00830	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
K6806_00835	COG1560	Kdo2-lipid A biosynthetic process
K6806_00840	COG1309	transcriptional regulator
K6806_00845	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
K6806_00855	COG2003	Belongs to the UPF0758 family
K6806_00900	COG0463	Glycosyl transferase, family 2
K6806_00905	COG0859	PFAM glycosyl transferase family 9
K6806_00910	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
K6806_00915	COG3642	lipopolysaccharide core region biosynthetic process
K6806_00935	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
K6806_00950	COG1519	Transferase
K6806_00955	COG0859	PFAM glycosyl transferase family 9
K6806_00960	COG1560	Kdo2-lipid A biosynthetic process
K6806_00970	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
K6806_01005	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
K6806_01010	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
K6806_01020	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
K6806_01025	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
K6806_01030	COG2089	acid synthase
K6806_01040	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
K6806_01045	COG1083	cytidylyl-transferase
K6806_01085	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
K6806_01090	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
K6806_01095	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
K6806_01100	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
K6806_01105	COG1215	transferase activity, transferring glycosyl groups
K6806_01130	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
K6806_01140	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
K6806_01160	COG0149	triose-phosphate isomerase activity
K6806_01190	COG1494	fructose-1,6-bisphosphatase
K6806_01200	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
K6806_01205	COG1575	Belongs to the MenA family. Type 1 subfamily
K6806_01210	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
K6806_01215	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
K6806_01225	COG1609	Transcriptional regulator
K6806_01230	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
K6806_01235	COG0254	rRNA binding
K6806_01245	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
K6806_01250	COG0088	Forms part of the polypeptide exit tunnel
K6806_01260	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
K6806_01265	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
K6806_01270	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
K6806_01275	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
K6806_01285	COG0255	Belongs to the universal ribosomal protein uL29 family
K6806_01290	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
K6806_01300	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
K6806_01305	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
K6806_01315	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
K6806_01320	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
K6806_01335	COG1841	ribosomal large subunit assembly
K6806_01340	COG0200	Binds to the 23S rRNA
K6806_01345	COG0201	protein transport
K6806_01350	COG0257	Belongs to the bacterial ribosomal protein bL36 family
K6806_01355	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
K6806_01360	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
K6806_01370	COG0202	RNA polymerase activity
K6806_01375	COG0203	ribosomal protein L17
K6806_01385	COG0545	Peptidyl-prolyl cis-trans isomerase
K6806_01395	COG2153	protein acetylation
K6806_01400	COG0513	Belongs to the DEAD box helicase family
K6806_01415	COG1648	precorrin-2 dehydrogenase activity
K6806_01415	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
K6806_01420	COG0175	sulfate reduction
K6806_01425	COG2895	sulfate adenylyltransferase (ATP) activity
K6806_01430	COG3273	potassium ion transport
K6806_01430	COG0471	metal ion transport
K6806_01435	COG0529	Catalyzes the synthesis of activated sulfate
K6806_01455	COG4181	ATPase activity
K6806_01470	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
K6806_01480	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
K6806_01485	COG0729	surface antigen
K6806_01490	COG2911	Protein conserved in bacteria
K6806_01495	COG2105	PFAM AIG2 family protein
K6806_01505	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
K6806_01510	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
K6806_01515	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
K6806_01520	COG0163	prenyltransferase activity
K6806_01525	COG4143	(ABC) transporter
K6806_01530	COG1178	ABC-type Fe3 transport system permease component
K6806_01535	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
K6806_01540	COG0583	DNA-binding transcription factor activity
K6806_01545	COG1902	pentaerythritol trinitrate reductase activity
K6806_01560	COG2358	TRAP transporter, solute receptor (TAXI family
K6806_01580	COG0142	geranyltranstransferase activity
K6806_01585	COG0261	This protein binds to 23S rRNA in the presence of protein L20
K6806_01595	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
K6806_01600	COG2966	Psort location CytoplasmicMembrane, score
K6806_01615	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
K6806_01620	COG2967	ApaG domain
K6806_01625	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
K6806_01630	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
K6806_01635	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
K6806_01640	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
K6806_01645	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
K6806_01665	COG0473	3-isopropylmalate dehydrogenase activity
K6806_01670	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
K6806_01690	COG0583	DNA-binding transcription factor activity
K6806_01695	COG1022	Amp-dependent synthetase and ligase
K6806_01700	COG0028	Belongs to the TPP enzyme family
K6806_01705	COG0440	acetolactate synthase activity
K6806_01720	COG0469	pyruvate kinase activity
K6806_01725	COG1349	DNA-binding transcription factor activity
K6806_01730	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
K6806_01740	COG2376	Dihydroxyacetone kinase
K6806_01745	COG1461	Dihydroxyacetone kinase
K6806_01760	COG3722	fumarate hydratase activity
K6806_01770	COG2213	PTS system mannitol-specific
K6806_01770	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
K6806_01795	COG0582	viral genome integration into host DNA
K6806_01850	COG0358	DNA primase activity
K6806_01855	COG1610	YqeY-like protein
K6806_01860	COG0828	Belongs to the bacterial ribosomal protein bS21 family
K6806_01865	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
K6806_01870	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
K6806_01875	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
K6806_01880	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
K6806_01885	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
K6806_01890	COG1968	undecaprenyl-diphosphatase activity
K6806_01900	COG3267	Type II secretory pathway component ExeA
K6806_01900	COG3409	Peptidoglycan-binding domain 1 protein
K6806_01910	COG0405	Gamma-glutamyltransferase
K6806_01915	COG4991	sh3 domain protein
K6806_01920	COG0306	phosphate transporter
K6806_01925	COG1392	Phosphate transport regulator
K6806_01930	COG3025	triphosphatase activity
K6806_01945	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
K6806_01950	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
K6806_01950	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
K6806_01955	COG1538	Outer membrane efflux protein
K6806_01960	COG0494	nUDIX hydrolase
K6806_01965	COG3151	Protein conserved in bacteria
K6806_01975	COG3150	esterase
K6806_01985	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
K6806_01990	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
K6806_02000	COG3105	Protein conserved in bacteria
K6806_02005	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
K6806_02015	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
K6806_02020	COG0723	plastoquinol--plastocyanin reductase activity
K6806_02025	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
K6806_02030	COG2857	Cytochrome c1
K6806_02035	COG0625	glutathione transferase activity
K6806_02040	COG2969	positive regulation of protein catabolic process
K6806_02045	COG2823	Periplasmic or secreted lipoprotein
K6806_02050	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
K6806_02065	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
K6806_02080	COG3116	cell division
K6806_02085	COG0768	penicillin binding
K6806_02090	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
K6806_02095	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
K6806_02100	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
K6806_02105	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
K6806_02110	COG0772	Belongs to the SEDS family
K6806_02125	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
K6806_02130	COG0849	cell division
K6806_02135	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
K6806_02140	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
K6806_02150	COG0653	protein targeting
K6806_02155	COG0494	nUDIX hydrolase
K6806_02165	COG0505	Belongs to the CarA family
K6806_02170	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
K6806_02185	COG0730	response to heat
K6806_02190	COG0583	DNA-binding transcription factor activity
K6806_02195	COG2860	membrane
K6806_02210	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
K6806_02220	COG0493	'glutamate synthase
K6806_02225	COG0067	glutamate synthase
K6806_02225	COG0070	glutamate synthase
K6806_02225	COG0069	glutamate synthase activity
K6806_02235	COG0067	glutamate synthase
K6806_02235	COG0070	glutamate synthase
K6806_02235	COG0069	glutamate synthase activity
K6806_02240	COG1242	4 iron, 4 sulfur cluster binding
K6806_02245	COG2203	Gaf domain
K6806_02245	COG3706	GGDEF domain
K6806_02245	COG4251	negative regulation of phosphorylation
K6806_02245	COG5001	Diguanylate cyclase
K6806_02250	COG0784	Response regulator, receiver
K6806_02250	COG5002	protein histidine kinase activity
K6806_02250	COG2198	Histidine kinase
K6806_02260	COG0745	RESPONSE REGULATOR receiver
K6806_02270	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
K6806_02290	COG0083	homoserine kinase activity
K6806_02295	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
K6806_02305	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
K6806_02310	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
K6806_02315	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
K6806_02330	COG1115	amino acid carrier protein
K6806_02335	COG3022	response to hydroperoxide
K6806_02340	COG0513	Belongs to the DEAD box helicase family
K6806_02345	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
K6806_02355	COG0716	FMN binding
K6806_02360	COG4974	Belongs to the 'phage' integrase family
K6806_02365	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
K6806_02370	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
K6806_02385	COG2204	response regulator
K6806_02395	COG0667	Aldo Keto reductase
K6806_02420	COG0730	response to heat
K6806_02425	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
K6806_02430	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
K6806_02440	COG1283	sodium-dependent phosphate transmembrane transporter activity
K6806_02445	COG0583	DNA-binding transcription factor activity
K6806_02450	COG0640	Transcriptional regulator
K6806_02455	COG0268	Binds directly to 16S ribosomal RNA
K6806_02460	COG0728	peptidoglycan biosynthetic process
K6806_02465	COG0196	riboflavin kinase activity
K6806_02480	COG1047	Peptidyl-prolyl cis-trans
K6806_02485	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
K6806_02495	COG3279	Response regulator of the LytR AlgR family
K6806_02500	COG3275	phosphorelay sensor kinase activity
K6806_02505	COG1966	Carbon starvation protein
K6806_02525	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
K6806_02530	COG1472	Belongs to the glycosyl hydrolase 3 family
K6806_02535	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
K6806_02540	COG1605	Chorismate mutase
K6806_02540	COG0287	Prephenate dehydrogenase
K6806_02545	COG0739	heme binding
K6806_02555	COG0488	(ABC) transporter
K6806_02565	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
K6806_02570	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
K6806_02575	COG0077	Prephenate dehydratase
K6806_02575	COG1605	Chorismate mutase
K6806_02580	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
K6806_02590	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
K6806_02595	COG0564	pseudouridine synthase activity
K6806_02605	COG0542	response to heat
K6806_02660	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
K6806_02665	COG0826	peptidase U32
K6806_02670	COG2974	May be involved in recombination
K6806_02675	COG0745	RESPONSE REGULATOR receiver
K6806_02680	COG5002	protein histidine kinase activity
K6806_02690	COG0248	Ppx GppA phosphatase
K6806_02695	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
K6806_02700	COG0573	inorganic phosphate transmembrane transporter activity
K6806_02705	COG0581	inorganic phosphate transmembrane transporter activity
K6806_02710	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
K6806_02715	COG0704	Plays a role in the regulation of phosphate uptake
K6806_02725	COG3142	Participates in the control of copper homeostasis
K6806_02730	COG0450	alkyl hydroperoxide reductase
K6806_02735	COG0583	DNA-binding transcription factor activity
K6806_02740	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
K6806_02750	COG0517	IMP dehydrogenase activity
K6806_02760	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
K6806_02770	COG1862	Preprotein translocase
K6806_02775	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
K6806_02780	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
K6806_02795	COG0483	inositol monophosphate 1-phosphatase activity
K6806_02800	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
K6806_02810	COG1104	cysteine desulfurase activity
K6806_02815	COG0822	iron-sulfur transferase activity
K6806_02830	COG0443	Heat shock 70 kDa protein
K6806_02835	COG0633	Ferredoxin
K6806_02840	COG2975	iron-sulfur cluster assembly
K6806_02850	COG0105	UTP biosynthetic process
K6806_02865	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
K6806_02870	COG0124	histidyl-tRNA synthetase
K6806_02875	COG2976	Protein conserved in bacteria
K6806_02880	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
K6806_02885	COG1160	GTP binding
K6806_02905	COG0516	GMP reductase activity
K6806_02905	COG0517	IMP dehydrogenase activity
K6806_02915	COG1757	Na H antiporter
K6806_02925	COG1584	GPR1 FUN34 yaaH family protein
K6806_02930	COG1115	amino acid carrier protein
K6806_02945	COG2873	o-acetylhomoserine
K6806_02950	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
K6806_02970	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
K6806_02970	COG3153	acetyltransferase
K6806_02975	COG0583	DNA-binding transcription factor activity
K6806_02995	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
K6806_03000	COG2867	negative regulation of translational initiation
K6806_03005	COG2914	Belongs to the UPF0125 (RnfH) family
K6806_03010	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
K6806_03020	COG0497	DNA recombination
K6806_03030	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
K6806_03035	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
K6806_03040	COG1301	dicarboxylic acid transport
K6806_03050	COG0484	heat shock protein binding
K6806_03080	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
K6806_03090	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
K6806_03095	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
K6806_03095	COG0047	phosphoribosylformylglycinamidine synthase activity
K6806_03110	COG1629	transport
K6806_03125	COG2195	Cleaves the N-terminal amino acid of tripeptides
K6806_03130	COG2252	PERMEase
K6806_03135	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
K6806_03140	COG1073	alpha beta
K6806_03150	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
K6806_03155	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
K6806_03160	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
K6806_03165	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
K6806_03165	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
K6806_03180	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
K6806_03190	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
K6806_03195	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
K6806_03200	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
K6806_03205	COG0142	geranyltranstransferase activity
K6806_03210	COG1722	exodeoxyribonuclease VII activity
K6806_03215	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
K6806_03225	COG0301	tRNA thio-modification
K6806_03225	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
K6806_03230	COG0583	DNA-binding transcription factor activity
K6806_03240	COG2363	Small membrane protein
K6806_03250	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
K6806_03255	COG1611	Belongs to the LOG family
K6806_03270	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
K6806_03270	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
K6806_03280	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
K6806_03285	COG1464	Belongs to the NlpA lipoprotein family
K6806_03290	COG2011	ABC-type metal ion transport system permease component
K6806_03295	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
K6806_03300	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
K6806_03310	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
K6806_03310	COG1263	PTS System
K6806_03315	COG0366	Alpha amylase catalytic
K6806_03330	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
K6806_03335	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
K6806_03340	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
K6806_03345	COG0321	lipoyl(octanoyl) transferase activity
K6806_03355	COG1686	Belongs to the peptidase S11 family
K6806_03360	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
K6806_03365	COG0772	Belongs to the SEDS family
K6806_03370	COG0768	penicillin binding
K6806_03375	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
K6806_03380	COG0799	negative regulation of ribosome biogenesis
K6806_03385	COG1466	dna polymerase III delta subunit
K6806_03390	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
K6806_03395	COG0495	leucyl-tRNA aminoacylation
K6806_03400	COG2888	peptidyl-tyrosine sulfation
K6806_03405	COG0815	Transfers the fatty acyl group on membrane lipoproteins
K6806_03410	COG4535	Mg2 and Co2 transporter CorC
K6806_03415	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
K6806_03420	COG1702	phosphate starvation-inducible protein PhoH
K6806_03425	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
K6806_03430	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
K6806_03535	COG0012	GTP binding
K6806_03540	COG0193	aminoacyl-tRNA hydrolase activity
K6806_03545	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
K6806_03550	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
K6806_03555	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
K6806_03560	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
K6806_03570	COG2890	protein-(glutamine-N5) methyltransferase activity
K6806_03575	COG3094	Invasion gene expression up-regulator, SirB
K6806_03580	COG2912	Transglutaminase-like superfamily
K6806_03585	COG2877	3-deoxy-8-phosphooctulonate synthase activity
K6806_03590	COG0737	Belongs to the 5'-nucleotidase family
K6806_03595	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
K6806_03600	COG1187	pseudouridine synthase activity
K6806_03605	COG2840	Smr protein MutS2
K6806_03645	COG2217	Heavy metal translocating P-type atpase
K6806_03645	COG2608	mercury ion transmembrane transporter activity
K6806_03655	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
K6806_03710	COG0784	Response regulator, receiver
K6806_03710	COG0835	chemotaxis
K6806_03715	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
K6806_03720	COG1815	bacterial-type flagellum-dependent cell motility
K6806_03725	COG1558	bacterial-type flagellum-dependent cell motility
K6806_03735	COG1749	Flagellar hook protein flgE
K6806_03740	COG4787	bacterial-type flagellum-dependent cell motility
K6806_03750	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
K6806_03755	COG1706	bacterial-type flagellum-dependent cell motility
K6806_03760	COG1705	Flagellar rod assembly protein muramidase FlgJ
K6806_03760	COG3951	Flagellar rod assembly protein muramidase FlgJ
K6806_03770	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
K6806_03775	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
K6806_03780	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
K6806_03785	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
K6806_03790	COG2190	(PTS) system
K6806_03795	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
K6806_03800	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
K6806_03805	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
K6806_03810	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
K6806_03815	COG3115	cell septum assembly
K6806_03820	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
K6806_03840	COG0330	HflC and HflK could
K6806_03845	COG2194	sulfuric ester hydrolase activity
K6806_03865	COG1192	Involved in chromosome partitioning
K6806_03870	COG1215	transferase activity, transferring glycosyl groups
K6806_03880	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
K6806_03890	COG3118	belongs to the thioredoxin family
K6806_03895	COG0300	oxidoreductase activity
K6806_03900	COG1090	epimerase
K6806_03925	COG0622	Phosphoesterase
K6806_03945	COG3710	Transcriptional regulator
K6806_03950	COG0326	Molecular chaperone. Has ATPase activity
K6806_03960	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
K6806_03965	COG3104	oligopeptide transport
K6806_03970	COG0250	Participates in transcription elongation, termination and antitermination
K6806_03975	COG0367	asparagine synthase
K6806_03980	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
K6806_03980	COG4651	solute:proton antiporter activity
K6806_03985	COG1846	Transcriptional regulator
K6806_03985	COG1940	carbohydrate kinase activity
K6806_03990	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
K6806_03995	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
K6806_03995	COG2190	(PTS) system
K6806_03995	COG1263	PTS System
K6806_04000	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
K6806_04005	COG0735	belongs to the Fur family
K6806_04015	COG0716	FMN binding
K6806_04025	COG0596	Alpha beta hydrolase
K6806_04030	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
K6806_04035	COG0033	Phosphoglucomutase
K6806_04045	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
K6806_04060	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
K6806_04065	COG1053	succinate dehydrogenase
K6806_04070	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
K6806_04075	COG0567	Dehydrogenase, E1 component
K6806_04080	COG0508	dehydrogenase complex catalyzes the overall conversion of
K6806_04085	COG0045	succinate-CoA ligase (ADP-forming) activity
K6806_04095	COG1108	ABC-type Mn2 Zn2 transport systems permease components
K6806_04100	COG1121	(ABC) transporter
K6806_04105	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
K6806_04110	COG4977	sequence-specific DNA binding
K6806_04115	COG1918	ferrous iron import across plasma membrane
K6806_04140	COG0018	arginyl-trna synthetase
K6806_04145	COG3102	Protein conserved in bacteria
K6806_04160	COG0788	formyltetrahydrofolate deformylase activity
K6806_04165	COG1199	ATP-dependent helicase activity
K6806_04170	COG1214	PFAM Peptidase M22, glycoprotease
K6806_04180	COG3065	identical protein binding
K6806_04185	COG2267	carboxylic ester hydrolase activity
K6806_04190	COG0318	PFAM AMP-dependent synthetase and ligase
K6806_04195	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
K6806_04200	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
K6806_04205	COG2894	cell division
K6806_04210	COG0850	regulation of cytokinetic process
K6806_04215	COG3100	YcgL domain-containing protein
K6806_04220	COG2951	lytic endotransglycosylase activity
K6806_04230	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
K6806_04235	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
K6806_04250	COG1028	Short-chain dehydrogenase reductase Sdr
K6806_04260	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
K6806_04285	COG2986	histidine ammonia-lyase
K6806_04290	COG1216	Glycosyl transferase, family 2
K6806_04295	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
K6806_04310	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
K6806_04315	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
K6806_04350	COG0513	Belongs to the DEAD box helicase family
K6806_04355	COG0569	domain protein
K6806_04360	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
K6806_04375	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
K6806_04380	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
K6806_04385	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
K6806_04390	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
K6806_04405	COG0544	peptidyl-prolyl cis-trans isomerase activity
K6806_04415	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
K6806_04420	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
K6806_04425	COG0776	regulation of translation
K6806_04430	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
K6806_04435	COG1555	photosystem II stabilization
K6806_04450	COG0232	Belongs to the dGTPase family. Type 2 subfamily
K6806_04455	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
K6806_04460	COG0436	Aminotransferase
K6806_04465	COG1169	isochorismate synthase
K6806_04470	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
K6806_04480	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
K6806_04500	COG2855	membrane
K6806_04505	COG0477	Major facilitator Superfamily
K6806_04550	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
K6806_04555	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
K6806_04570	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
K6806_04575	COG1522	sequence-specific DNA binding
K6806_04585	COG1946	Acyl-CoA thioesterase
K6806_04590	COG3126	Type III secretion system lipoprotein chaperone (YscW)
K6806_04615	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
K6806_04620	COG0517	IMP dehydrogenase activity
K6806_04620	COG0516	GMP reductase activity
K6806_04645	COG0537	adenosine 5'-monophosphoramidase activity
K6806_04670	COG3150	esterase
K6806_04675	COG1252	NADH dehydrogenase
K6806_04690	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
K6806_04700	COG4591	ABC-type transport system involved in lipoprotein release permease component
K6806_04705	COG1136	(ABC) transporter
K6806_04710	COG4591	ABC-type transport system involved in lipoprotein release permease component
K6806_04720	COG2333	competence protein COMEC
K6806_04720	COG0658	competence protein
K6806_04725	COG1132	(ABC) transporter
K6806_04745	COG2719	SpoVR family
K6806_04750	COG2718	Belongs to the UPF0229 family
K6806_04755	COG2766	serine protein kinase
K6806_04760	COG3013	Belongs to the UPF0304 family
K6806_04770	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
K6806_04780	COG1882	Formate acetyltransferase
K6806_04820	COG0708	Exodeoxyribonuclease III
K6806_04830	COG3923	Primosomal replication protein n
K6806_04835	COG0730	response to heat
K6806_04840	COG1199	ATP-dependent helicase activity
K6806_04845	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
K6806_04850	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
K6806_04855	COG1187	pseudouridine synthase activity
K6806_04865	COG1278	Cold shock
K6806_04870	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
K6806_04875	COG0542	response to heat
K6806_04880	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
K6806_04885	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
K6806_04890	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
K6806_04910	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
K6806_04915	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
K6806_04920	COG0297	glycogen (starch) synthase activity
K6806_04940	COG3070	regulator of competence-specific genes
K6806_04945	COG1609	Transcriptional regulator
K6806_04950	COG3381	protein complex oligomerization
K6806_04955	COG0745	RESPONSE REGULATOR receiver
K6806_04960	COG1434	Gram-negative-bacterium-type cell wall biogenesis
K6806_04965	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
K6806_04975	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
K6806_04980	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
K6806_05000	COG4067	protein conserved in archaea
K6806_05000	COG0189	ligase activity
K6806_05005	COG0500	methyltransferase
K6806_05015	COG1801	Protein of unknown function DUF72
K6806_05025	COG0217	transcriptional regulatory protein
K6806_05030	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
K6806_05035	COG0632	four-way junction helicase activity
K6806_05040	COG2255	four-way junction helicase activity
K6806_05045	COG1271	oxidase subunit
K6806_05050	COG1294	oxidase, subunit
K6806_05055	COG4890	Cyd operon protein YbgT
K6806_05065	COG0824	Thioesterase
K6806_05070	COG0811	peptide transport
K6806_05085	COG0823	Involved in the tonB-independent uptake of proteins
K6806_05090	COG2885	chlorophyll binding
K6806_05095	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
K6806_05100	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
K6806_05110	COG3766	membrane
K6806_05120	COG0754	glutathionylspermidine amidase activity
K6806_05130	COG0784	Response regulator, receiver
K6806_05130	COG5002	protein histidine kinase activity
K6806_05145	COG1294	oxidase, subunit
K6806_05150	COG1271	oxidase subunit
K6806_05170	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
K6806_05175	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
K6806_05200	COG3568	Endonuclease Exonuclease Phosphatase
K6806_05225	COG0583	DNA-binding transcription factor activity
K6806_05235	COG0686	Belongs to the AlaDH PNT family
K6806_05245	COG1674	ftsk spoiiie
K6806_05255	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
K6806_05275	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
K6806_05280	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
K6806_05300	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
K6806_05320	COG0300	oxidoreductase activity
K6806_05335	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
K6806_05345	COG2268	Band 7 protein
K6806_05355	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
K6806_05360	COG2915	High frequency lysogenization protein hflD homolog
K6806_05375	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
K6806_05385	COG1757	Na H antiporter
K6806_05395	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
K6806_05405	COG0131	Imidazoleglycerol-phosphate dehydratase
K6806_05405	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
K6806_05410	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
K6806_05415	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
K6806_05425	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
K6806_05425	COG0140	phosphoribosyl-ATP diphosphatase activity
K6806_05430	COG3012	SEC-C Motif Domain Protein
K6806_05435	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
K6806_05440	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
K6806_05445	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
K6806_05450	COG0215	cysteine-tRNA ligase activity
K6806_05455	COG1435	thymidine kinase activity
K6806_05485	COG2116	formate transmembrane transporter activity
K6806_05495	COG0390	transport system, permease component
K6806_05500	COG4459	periplasmic nitrate reductase
K6806_05505	COG3005	denitrification pathway
K6806_05510	COG0243	molybdopterin cofactor binding
K6806_05525	COG1227	inorganic diphosphatase activity
K6806_05535	COG4172	Belongs to the ABC transporter superfamily
K6806_05545	COG4171	peptide transport system, permease
K6806_05560	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
K6806_05565	COG1842	Phage shock protein A
K6806_05575	COG1983	PspC domain protein
K6806_05595	COG2818	Glycosylase
K6806_05600	COG5380	lipid catabolic process
K6806_05605	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
K6806_05610	COG0626	cystathionine gamma-synthase activity
K6806_05620	COG0733	neurotransmitter:sodium symporter activity
K6806_05625	COG0564	pseudouridine synthase activity
K6806_05635	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
K6806_05640	COG1151	hydroxylamine reductase activity
K6806_05645	COG3604	Transcriptional regulator
K6806_05655	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
K6806_05660	COG4136	ATPase activity
K6806_05665	COG4135	transport system, permease component
K6806_05670	COG4134	Bacterial extracellular solute-binding protein
K6806_05680	COG3313	Fe-S protein
K6806_05700	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
K6806_05720	COG1061	Type III restriction enzyme res subunit
K6806_05725	COG1187	pseudouridine synthase activity
K6806_05730	COG2814	Major facilitator Superfamily
K6806_05740	COG0702	epimerase
K6806_05745	COG0534	Mate efflux family protein
K6806_05765	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
K6806_05775	COG1960	acyl-CoA dehydrogenase activity
K6806_05780	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
K6806_05785	COG2985	domain, Protein
K6806_05785	COG3273	potassium ion transport
K6806_05790	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
K6806_05800	COG1737	Transcriptional regulator
K6806_05805	COG0076	glutamate decarboxylase activity
K6806_05815	COG2431	L-lysine efflux transmembrane transporter activity
K6806_05825	COG3070	regulator of competence-specific genes
K6806_05840	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
K6806_05840	COG4191	Histidine kinase
K6806_05850	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
K6806_05860	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
K6806_05865	COG4988	ABC transporter
K6806_05870	COG0492	ferredoxin-NADP+ reductase activity
K6806_05895	COG0471	metal ion transport
K6806_05900	COG2949	membrane
K6806_05905	COG0281	malic enzyme
K6806_05910	COG1643	Atp-dependent helicase
K6806_05925	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
K6806_05960	COG0247	lactate metabolic process
K6806_05960	COG0277	FAD linked oxidase domain protein
K6806_05975	COG2986	histidine ammonia-lyase
K6806_05980	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
K6806_05985	COG0010	Belongs to the arginase family
K6806_05990	COG1228	amidohydrolase
K6806_05995	COG2188	Transcriptional regulator
K6806_06010	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
K6806_06020	COG0291	Belongs to the bacterial ribosomal protein bL35 family
K6806_06030	COG0393	Putative heavy-metal-binding
K6806_06065	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
K6806_06070	COG0072	phenylalanine-tRNA ligase activity
K6806_06070	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
K6806_06080	COG0776	regulation of translation
K6806_06090	COG0500	methyltransferase
K6806_06095	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
K6806_06100	COG0295	cytidine deaminase activity
K6806_06105	COG1346	cytolysis
K6806_06110	COG1380	Effector of murein hydrolase LrgA
K6806_06115	COG2925	Exonuclease
K6806_06120	COG1823	symporter activity
K6806_06125	COG0702	epimerase
K6806_06130	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
K6806_06135	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
K6806_06155	COG2988	succinylglutamate desuccinylase activity
K6806_06160	COG4139	cobalamin transport
K6806_06165	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
K6806_06185	COG0583	DNA-binding transcription factor activity
K6806_06195	COG1451	nucleotide metabolic process
K6806_06230	COG3938	Belongs to the proline racemase family
K6806_06245	COG2423	ornithine cyclodeaminase activity
K6806_06250	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
K6806_06255	COG3842	ATPase activity
K6806_06260	COG1176	ABC-type spermidine putrescine transport system, permease component I
K6806_06265	COG1177	transmembrane transport
K6806_06280	COG3291	Pkd domain containing protein
K6806_06295	COG0444	Belongs to the ABC transporter superfamily
K6806_06300	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
K6806_06305	COG0601	transmembrane transport
K6806_06315	COG2195	Cleaves the N-terminal amino acid of tripeptides
K6806_06325	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
K6806_06335	COG0625	glutathione transferase activity
K6806_06440	COG1278	Cold shock
K6806_06445	COG0557	exoribonuclease II activity
K6806_06505	COG1783	phage Terminase large subunit
K6806_06710	COG3755	Protein conserved in bacteria
K6806_06735	COG1742	UPF0060 membrane protein
K6806_06750	COG1757	Na H antiporter
K6806_06755	COG0174	glutamine synthetase
K6806_06760	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
K6806_06765	COG1396	sequence-specific DNA binding
K6806_06765	COG1917	Cupin 2, conserved barrel domain protein
K6806_06770	COG1012	belongs to the aldehyde dehydrogenase family
K6806_06775	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
K6806_06785	COG2957	Belongs to the agmatine deiminase family
K6806_06790	COG1012	belongs to the aldehyde dehydrogenase family
K6806_06795	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
K6806_06800	COG2200	EAL domain
K6806_06810	COG1846	Transcriptional regulator
K6806_06815	COG2315	Protein conserved in bacteria
K6806_06855	COG3063	Type IV pilus biogenesis stability protein PilW
K6806_06860	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
K6806_06875	COG1560	Kdo2-lipid A biosynthetic process
K6806_06880	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
K6806_06885	COG1280	lysine exporter protein (LysE YggA)
K6806_06895	COG1115	amino acid carrier protein
K6806_06920	COG1368	sulfuric ester hydrolase activity
K6806_06925	COG2113	Glycine betaine
K6806_06930	COG4176	ABC-type proline glycine betaine transport system permease component
K6806_06935	COG4175	Glycine betaine
K6806_06950	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
K6806_06955	COG0456	acetyltransferase
K6806_06960	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
K6806_06965	COG0662	Cupin 2, conserved barrel domain protein
K6806_06970	COG0527	aspartate kinase activity
K6806_06980	COG3119	arylsulfatase activity
K6806_06995	COG0641	radical SAM
K6806_07010	COG3119	arylsulfatase activity
K6806_07035	COG1538	Outer membrane efflux protein
K6806_07050	COG1349	DNA-binding transcription factor activity
K6806_07055	COG0673	inositol 2-dehydrogenase activity
K6806_07060	COG4702	Belongs to the UPF0303 family
K6806_07085	COG0471	metal ion transport
K6806_07100	COG5001	Diguanylate cyclase
K6806_07100	COG3300	MHYT domain
K6806_07115	COG1328	CTP reductase activity
K6806_07120	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
K6806_07130	COG0861	Integral membrane protein TerC family
K6806_07140	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
K6806_07150	COG0814	amino acid
K6806_07165	COG1120	ATPase activity
K6806_07170	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
K6806_07180	COG4774	siderophore transport
K6806_07190	COG1132	(ABC) transporter
K6806_07195	COG1132	(ABC) transporter
K6806_07215	COG0583	DNA-binding transcription factor activity
K6806_07240	COG0443	Heat shock 70 kDa protein
K6806_07245	COG0443	Heat shock 70 kDa protein
K6806_07290	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
K6806_07295	COG1643	Atp-dependent helicase
K6806_07310	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
K6806_07320	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
K6806_07325	COG1215	transferase activity, transferring glycosyl groups
K6806_07330	COG0438	transferase activity, transferring glycosyl groups
K6806_07360	COG0438	transferase activity, transferring glycosyl groups
K6806_07365	COG0297	glycogen (starch) synthase activity
K6806_07370	COG2204	response regulator
K6806_07400	COG1793	dna ligase
K6806_07410	COG0534	Mate efflux family protein
K6806_07415	COG0307	riboflavin synthase, alpha
K6806_07425	COG3001	Fructosamine kinase
K6806_07435	COG3706	GGDEF domain
K6806_07445	COG0791	NLP P60 protein
K6806_07480	COG3148	PFAM DTW domain containing protein
K6806_07485	COG1940	carbohydrate kinase activity
K6806_07495	COG0303	'Molybdopterin
K6806_07500	COG0746	molybdenum cofactor guanylyltransferase activity
K6806_07505	COG3842	ATPase activity
K6806_07520	COG2204	response regulator
K6806_07525	COG4191	Histidine kinase
K6806_07530	COG0488	(ABC) transporter
K6806_07535	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
K6806_07565	COG3383	formate dehydrogenase (NAD+) activity
K6806_07565	COG0243	molybdopterin cofactor binding
K6806_07570	COG0437	4 iron, 4 sulfur cluster binding
K6806_07595	COG0004	ammonium transporteR
K6806_07605	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
K6806_07610	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
K6806_07620	COG1177	transmembrane transport
K6806_07630	COG3842	ATPase activity
K6806_07655	COG0589	response to stress
K6806_07660	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
K6806_07675	COG2217	Heavy metal translocating P-type atpase
K6806_07685	COG2010	Cytochrome c
K6806_07700	COG3278	Belongs to the heme-copper respiratory oxidase family
K6806_07715	COG0784	Response regulator, receiver
K6806_07715	COG2205	protein histidine kinase activity
K6806_07725	COG3120	sequence-specific DNA binding
K6806_07730	COG1067	ATP-dependent peptidase activity
K6806_07735	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
K6806_07750	COG0488	(ABC) transporter
K6806_07760	COG0116	Belongs to the methyltransferase superfamily
K6806_07760	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
K6806_07770	COG0167	dihydroorotate dehydrogenase activity
K6806_07775	COG2902	Dehydrogenase
K6806_07785	COG0308	aminopeptidase N
K6806_07800	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
K6806_07805	COG1956	GAF domain-containing protein
K6806_07810	COG1132	(ABC) transporter
K6806_07815	COG2995	paraquat-inducible protein a
K6806_07820	COG3008	intermembrane lipid transfer
K6806_07845	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
K6806_07850	COG1666	GTP binding
K6806_07860	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
K6806_07865	COG4597	amino acid ABC transporter
K6806_07870	COG0765	amino acid transport
K6806_07875	COG1126	abc transporter atp-binding protein
K6806_07880	COG0670	Belongs to the BI1 family
K6806_07890	COG2920	part of a sulfur-relay system
K6806_07895	COG1254	Belongs to the acylphosphatase family
K6806_07900	COG0840	transmembrane signaling receptor activity
K6806_07920	COG2885	chlorophyll binding
K6806_07925	COG2801	Transposase and inactivated derivatives
K6806_07950	COG2199	diguanylate cyclase activity
K6806_07950	COG2203	Gaf domain
K6806_07955	COG1414	Transcriptional regulator
K6806_07965	COG0656	L-ascorbic acid biosynthetic process
K6806_07970	COG0583	DNA-binding transcription factor activity
K6806_07980	COG0583	DNA-binding transcription factor activity
K6806_07985	COG2814	Major facilitator Superfamily
K6806_08005	COG1335	isochorismatase
K6806_08010	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
K6806_08025	COG1410	methionine synthase
K6806_08025	COG0646	methionine synthase
K6806_08030	COG1126	abc transporter atp-binding protein
K6806_08035	COG0765	amino acid transport
K6806_08040	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
K6806_08055	COG0583	DNA-binding transcription factor activity
K6806_08070	COG0583	DNA-binding transcription factor activity
K6806_08075	COG0583	DNA-binding transcription factor activity
K6806_08090	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
K6806_08095	COG0602	queuosine metabolic process
K6806_08100	COG0561	phosphatase activity
K6806_08125	COG2828	Protein conserved in bacteria
K6806_08135	COG0372	Belongs to the citrate synthase family
K6806_08140	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
K6806_08175	COG0730	response to heat
K6806_08180	COG2358	TRAP transporter, solute receptor (TAXI family
K6806_08205	COG0457	Tetratricopeptide repeat
K6806_08275	COG4790	Type iii secretion
K6806_08280	COG4794	Type iii secretion
K6806_08285	COG4791	protein targeting
K6806_08290	COG4792	protein secretion
K6806_08295	COG2207	Transcriptional regulator
K6806_08325	COG3177	Filamentation induced by cAMP protein fic
K6806_08345	COG4669	(LipO)protein
K6806_08415	COG1012	belongs to the aldehyde dehydrogenase family
K6806_08420	COG3284	Transcriptional regulator
K6806_08435	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
K6806_08440	COG0363	glucosamine-6-phosphate deaminase activity
K6806_08445	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
K6806_08450	COG2207	Transcriptional regulator
K6806_08460	COG4565	transcriptional regulatory protein
K6806_08465	COG3290	protein histidine kinase activity
K6806_08480	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
K6806_08495	COG0583	DNA-binding transcription factor activity
K6806_08510	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
K6806_08520	COG2985	domain, Protein
K6806_08545	COG2272	Belongs to the type-B carboxylesterase lipase family
K6806_08550	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
K6806_08555	COG0729	surface antigen
K6806_08565	COG1280	lysine exporter protein (LysE YggA)
K6806_08570	COG1280	lysine exporter protein (LysE YggA)
K6806_08575	COG5507	3-demethylubiquinone-9 3-methyltransferase
K6806_08595	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
K6806_08600	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K6806_08605	COG0110	maltose O-acetyltransferase activity
K6806_08685	COG2026	Addiction module toxin, RelE StbE family
K6806_08725	COG3668	Plasmid stabilization system
K6806_09000	COG2026	Addiction module toxin, RelE StbE family
K6806_09010	COG2824	Alkylphosphonate utilization operon protein PhnA
K6806_09055	COG0346	lactoylglutathione lyase activity
K6806_09510	COG2314	TM2 domain
K6806_09550	COG0791	NLP P60 protein
K6806_09560	COG1492	cobalamin metabolic process
K6806_09685	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K6806_09695	COG3768	UPF0283 membrane protein
K6806_09700	COG3106	COG3106 Predicted ATPase
K6806_09715	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
K6806_09720	COG0784	Response regulator, receiver
K6806_09720	COG2205	protein histidine kinase activity
K6806_09730	COG0494	nUDIX hydrolase
K6806_09735	COG0814	amino acid
K6806_09740	COG1760	l-serine dehydratase
K6806_09745	COG2200	EAL domain
K6806_09755	COG0720	synthase
K6806_09760	COG0840	transmembrane signaling receptor activity
K6806_09765	COG0017	Asparaginyl-tRNA synthetase
K6806_09775	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K6806_09790	COG1448	Aminotransferase
K6806_09810	COG0840	transmembrane signaling receptor activity
K6806_09815	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
K6806_09845	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
K6806_09860	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K6806_09865	COG3108	Peptidase M15
K6806_09870	COG2989	Protein conserved in bacteria
K6806_09895	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
K6806_09905	COG4235	cytochrome complex assembly
K6806_09905	COG3088	subunit of a heme lyase
K6806_09915	COG1138	Cytochrome C-type biogenesis protein
K6806_09920	COG3301	Polysulphide reductase, NrfD
K6806_09925	COG0437	4 iron, 4 sulfur cluster binding
K6806_09935	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
K6806_09955	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
K6806_09960	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
K6806_09990	COG0019	diaminopimelate decarboxylase activity
K6806_10035	COG0322	excinuclease ABC activity
K6806_10040	COG2197	response regulator
K6806_10045	COG0417	DNA replication proofreading
K6806_10065	COG1187	pseudouridine synthase activity
K6806_10075	COG0009	L-threonylcarbamoyladenylate synthase
K6806_10080	COG0613	PHP domain protein
K6806_10090	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
K6806_10095	COG0512	Glutamine amidotransferase of anthranilate synthase
K6806_10105	COG0135	phosphoribosylanthranilate isomerase activity
K6806_10105	COG0134	indole-3-glycerol-phosphate synthase activity
K6806_10115	COG0159	tryptophan synthase activity
K6806_10120	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
K6806_10125	COG0318	PFAM AMP-dependent synthetase and ligase
K6806_10130	COG1301	dicarboxylic acid transport
K6806_10150	COG2917	probably involved in intracellular septation
K6806_10160	COG2350	Protein conserved in bacteria
K6806_10170	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
K6806_10175	COG0583	DNA-binding transcription factor activity
K6806_10190	COG5001	Diguanylate cyclase
K6806_10195	COG1032	radical SAM domain protein
K6806_10220	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
K6806_10225	COG0463	Glycosyl transferase, family 2
K6806_10230	COG0745	RESPONSE REGULATOR receiver
K6806_10235	COG5002	protein histidine kinase activity
K6806_10235	COG3850	Histidine kinase
K6806_10290	COG0577	efflux transmembrane transporter activity
K6806_10290	COG1136	(ABC) transporter
K6806_10295	COG0577	efflux transmembrane transporter activity
K6806_10295	COG1136	(ABC) transporter
K6806_10300	COG1136	(ABC) transporter
K6806_10300	COG0577	efflux transmembrane transporter activity
K6806_10310	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
K6806_10330	COG3118	belongs to the thioredoxin family
K6806_10335	COG4232	protein-disulfide reductase activity
K6806_10370	COG2863	cytochrome
K6806_10375	COG3258	Cytochrome c
K6806_10380	COG2995	paraquat-inducible protein a
K6806_10385	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
K6806_10385	COG3008	intermembrane lipid transfer
K6806_10405	COG4166	transmembrane transport
K6806_10415	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
K6806_10420	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
K6806_10430	COG0539	negative regulation of cytoplasmic translation
K6806_10435	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
K6806_10440	COG0616	signal peptide processing
K6806_10445	COG1028	Short-chain dehydrogenase reductase Sdr
K6806_10460	COG0587	DNA-directed DNA polymerase activity
K6806_10465	COG0835	chemotaxis
K6806_10465	COG0784	Response regulator, receiver
K6806_10470	COG1940	carbohydrate kinase activity
K6806_10475	COG0469	pyruvate kinase activity
K6806_10480	COG4667	esterase of the alpha-beta hydrolase superfamily
K6806_10495	COG0733	neurotransmitter:sodium symporter activity
K6806_10510	COG1263	PTS System
K6806_10510	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
K6806_10515	COG0084	hydrolase, TatD family'
K6806_10520	COG0470	DNA polymerase III
K6806_10525	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
K6806_10530	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
K6806_10565	COG0416	fatty acid biosynthetic process
K6806_10575	COG1399	metal-binding, possibly nucleic acid-binding protein
K6806_10580	COG0424	maF-like protein
K6806_10585	COG0564	pseudouridine synthase activity
K6806_10590	COG1530	ribonuclease E activity
K6806_10595	COG0659	secondary active sulfate transmembrane transporter activity
K6806_10600	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
K6806_10605	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
K6806_10615	COG0572	uridine kinase
K6806_10625	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
K6806_10625	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
K6806_10635	COG2186	Transcriptional regulator
K6806_10640	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
K6806_10645	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
K6806_10650	COG3318	Belongs to the UPF0149 family
K6806_10650	COG3012	SEC-C Motif Domain Protein
K6806_10655	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
K6806_10660	COG3706	GGDEF domain
K6806_10665	COG0366	Alpha amylase catalytic
K6806_10670	COG1122	ATPase activity
K6806_10675	COG4120	Belongs to the binding-protein-dependent transport system permease family
K6806_10685	COG3092	negative regulation of chromosome organization
K6806_10690	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
K6806_10695	COG0280	phosphate acetyltransferase
K6806_10695	COG0857	belongs to the CobB CobQ family
K6806_10705	COG0435	Glutathione S-transferase
K6806_10715	COG0444	Belongs to the ABC transporter superfamily
K6806_10720	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
K6806_10725	COG0601	transmembrane transport
K6806_10735	COG0314	molybdopterin synthase activity
K6806_10740	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
K6806_10745	COG0315	cyclic pyranopterin monophosphate synthase activity
K6806_10750	COG0521	Mo-molybdopterin cofactor biosynthetic process
K6806_10755	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
K6806_10760	COG0391	Required for morphogenesis under gluconeogenic growth conditions
K6806_10765	COG2198	Histidine kinase
K6806_10770	COG2204	response regulator
K6806_10775	COG0556	nucleotide-excision repair
K6806_10785	COG1882	Formate acetyltransferase
K6806_10790	COG4657	Part of a membrane complex involved in electron transport
K6806_10795	COG2878	Part of a membrane complex involved in electron transport
K6806_10800	COG4656	Part of a membrane complex involved in electron transport
K6806_10805	COG4658	electron transport chain
K6806_10810	COG4659	FMN binding
K6806_10815	COG4660	Part of a membrane complex involved in electron transport
K6806_10820	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
K6806_10825	COG0346	lactoylglutathione lyase activity
K6806_10835	COG2885	chlorophyll binding
K6806_10840	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
K6806_10845	COG2056	Na+-H+ antiporter family
K6806_10935	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
K6806_10985	COG4695	Portal protein
K6806_11055	COG1401	restriction endodeoxyribonuclease activity
K6806_11065	COG4974	Belongs to the 'phage' integrase family
K6806_11070	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
K6806_11090	COG1012	belongs to the aldehyde dehydrogenase family
K6806_11090	COG1454	alcohol dehydrogenase
K6806_11095	COG2095	MarC family integral membrane protein
K6806_11100	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
K6806_11105	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
K6806_11110	COG1757	Na H antiporter
K6806_11125	COG3081	Nucleoid-associated protein
K6806_11130	COG3082	Protein of unknown function (DUF1414)
K6806_11145	COG0123	including yeast histone deacetylase and acetoin utilization protein
K6806_11160	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
K6806_11165	COG0778	Nitroreductase
K6806_11175	COG0446	pyridine nucleotide-disulphide oxidoreductase
K6806_11175	COG1902	pentaerythritol trinitrate reductase activity
K6806_11180	COG0616	signal peptide processing
K6806_11185	COG0252	asparaginase activity
K6806_11190	COG3139	Protein of unknown function (DUF1315)
K6806_11200	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
K6806_11205	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
K6806_11220	COG2226	methyltransferase
K6806_11235	COG1785	Belongs to the alkaline phosphatase family
K6806_11245	COG0346	lactoylglutathione lyase activity
K6806_11250	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
K6806_11255	COG0668	transmembrane transport
K6806_11260	COG2983	Belongs to the UPF0260 family
K6806_11265	COG2261	transglycosylase associated protein
K6806_11275	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
K6806_11280	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
K6806_11295	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
K6806_11300	COG2832	Protein of unknown function (DUF454)
K6806_11305	COG0745	RESPONSE REGULATOR receiver
K6806_11310	COG0583	DNA-binding transcription factor activity
K6806_11315	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
K6806_11320	COG1286	toxin biosynthetic process
K6806_11325	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
K6806_11330	COG0285	dihydrofolate synthase activity
K6806_11335	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
K6806_11350	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
K6806_11355	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
K6806_11360	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
K6806_11365	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
K6806_11365	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
K6806_11370	COG0431	NADPH-dependent FMN reductase
K6806_11380	COG3101	peptidyl-lysine hydroxylation
K6806_11385	COG2860	membrane
K6806_11390	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
K6806_11395	COG2890	protein-(glutamine-N5) methyltransferase activity
K6806_11400	COG2840	Smr protein MutS2
K6806_11405	COG2062	phosphohistidine phosphatase, SixA
K6806_11420	COG1250	3-hydroxyacyl-CoA dehydrogenase
K6806_11420	COG1024	Enoyl-CoA hydratase
K6806_11425	COG0183	Belongs to the thiolase family
K6806_11445	COG2067	long-chain fatty acid transport protein
K6806_11460	COG3088	subunit of a heme lyase
K6806_11460	COG4235	cytochrome complex assembly
K6806_11470	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
K6806_11475	COG1138	Cytochrome C-type biogenesis protein
K6806_11480	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
K6806_11485	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
K6806_11490	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
K6806_11495	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
K6806_11500	COG4133	protoheme IX ABC transporter activity
K6806_11510	COG0835	chemotaxis
K6806_11520	COG1192	Involved in chromosome partitioning
K6806_11525	COG2201	protein-glutamate methylesterase activity
K6806_11530	COG2198	Histidine kinase
K6806_11530	COG0643	Histidine kinase
K6806_11530	COG0784	Response regulator, receiver
K6806_11535	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
K6806_11575	COG1987	bacterial-type flagellum assembly
K6806_11630	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
K6806_11640	COG1677	Flagellar hook-basal body complex protein FliE
K6806_11660	COG1516	flagellar protein fliS
K6806_11670	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
K6806_11675	COG1334	flagellar protein FlaG
K6806_11680	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
K6806_11685	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
K6806_11690	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
K6806_11695	COG2837	iron assimilation
K6806_11720	COG1393	Belongs to the ArsC family
K6806_11725	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
K6806_11740	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
K6806_11745	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
K6806_11755	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
K6806_11770	COG4783	chaperone-mediated protein folding
K6806_11775	COG1393	Belongs to the ArsC family
K6806_11795	COG2233	PERMEase
K6806_11800	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
K6806_11805	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
K6806_11810	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
K6806_11820	COG0121	glutamine amidotransferase
K6806_11825	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
K6806_11830	COG1960	acyl-CoA dehydrogenase activity
K6806_11865	COG0328	RNA-DNA hybrid ribonuclease activity
K6806_11870	COG2226	methyltransferase
K6806_11875	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K6806_11880	COG0741	lytic transglycosylase activity
K6806_11880	COG1388	LysM domain
K6806_11890	COG3021	interspecies interaction between organisms
K6806_11895	COG0347	Belongs to the P(II) protein family
K6806_11910	COG0825	malonyl-CoA metabolic process
K6806_11915	COG0587	DNA-directed DNA polymerase activity
K6806_11925	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
K6806_11930	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
K6806_11940	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
K6806_11945	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
K6806_11955	COG0750	zinc metalloprotease
K6806_11960	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
K6806_11965	COG0575	Belongs to the CDS family
K6806_11970	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
K6806_11975	COG0233	cytoplasmic translational termination
K6806_11980	COG0528	UMP kinase activity
K6806_11985	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
K6806_11990	COG0052	Belongs to the universal ribosomal protein uS2 family
K6806_11995	COG0024	Methionine aminopeptidase
K6806_12000	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
K6806_12010	COG0564	pseudouridine synthase activity
K6806_12045	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
K6806_12050	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
K6806_12075	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
K6806_12085	COG0254	rRNA binding
K6806_12090	COG1720	tRNA m6t6A37 methyltransferase activity
K6806_12095	COG0442	prolyl-tRNA aminoacylation
K6806_12115	COG0733	neurotransmitter:sodium symporter activity
K6806_12130	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
K6806_12135	COG0514	ATP-dependent DNA helicase (RecQ)
K6806_12140	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
K6806_12160	COG1477	protein flavinylation
K6806_12165	COG2871	sodium ion transport
K6806_12170	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
K6806_12175	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
K6806_12180	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
K6806_12185	COG1805	sodium ion transport
K6806_12190	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
K6806_12195	COG0271	Belongs to the BolA IbaG family
K6806_12200	COG2813	Specifically methylates the guanine in position
K6806_12205	COG3056	Lipoprotein
K6806_12225	COG1595	DNA-templated transcription, initiation
K6806_12240	COG3248	Nucleoside-binding outer membrane protein
K6806_12245	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
K6806_12250	COG0693	protein deglycase activity
K6806_12255	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
K6806_12260	COG3706	GGDEF domain
K6806_12265	COG2166	iron-sulfur cluster assembly
K6806_12270	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
K6806_12275	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
K6806_12285	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
K6806_12285	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
K6806_12305	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
K6806_12310	COG1074	ATP-dependent DNA helicase activity
K6806_12315	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
K6806_12335	COG3141	response to X-ray
K6806_12355	COG2171	N-acyltransferase activity
K6806_12360	COG0584	glycerophosphoryl diester phosphodiesterase
K6806_12365	COG2271	Major facilitator Superfamily
K6806_12370	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
K6806_12375	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
K6806_12380	COG1349	DNA-binding transcription factor activity
K6806_12385	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
K6806_12390	COG0598	Magnesium transport protein CorA
K6806_12410	COG1609	Transcriptional regulator
K6806_12415	COG0583	DNA-binding transcription factor activity
K6806_12455	COG1022	Amp-dependent synthetase and ligase
K6806_12465	COG0583	DNA-binding transcription factor activity
K6806_12470	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
K6806_12475	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
K6806_12485	COG0560	Phosphoserine phosphatase
K6806_12495	COG0813	purine-nucleoside phosphorylase activity
K6806_12500	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
K6806_12505	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
K6806_12510	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
K6806_12515	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
K6806_12520	COG0084	hydrolase, TatD family'
K6806_12550	COG3153	acetyltransferase
K6806_12555	COG3154	lipid carrier protein
K6806_12565	COG0826	peptidase U32
K6806_12570	COG0826	peptidase U32
K6806_12575	COG0534	Mate efflux family protein
K6806_12590	COG1185	polyribonucleotide nucleotidyltransferase activity
K6806_12595	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
K6806_12600	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
K6806_12605	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
K6806_12610	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
K6806_12615	COG0195	Participates in both transcription termination and antitermination
K6806_12620	COG0779	Required for maturation of 30S ribosomal subunits
K6806_12635	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
K6806_12640	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
K6806_12645	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
K6806_12650	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
K6806_12655	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
K6806_12660	COG1534	Rna-binding protein
K6806_12665	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
K6806_12670	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
K6806_12675	COG2027	D-alanyl-D-alanine carboxypeptidase
K6806_12685	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
K6806_12690	COG0739	heme binding
K6806_12715	COG0628	permease
K6806_12725	COG2205	protein histidine kinase activity
K6806_12725	COG0784	Response regulator, receiver
K6806_12730	COG0747	negative chemotaxis
K6806_12740	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
K6806_12745	COG0444	Belongs to the ABC transporter superfamily
K6806_12750	COG4608	Belongs to the ABC transporter superfamily
K6806_12760	COG2971	BadF BadG BcrA BcrD
K6806_12775	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
K6806_12780	COG3842	ATPase activity
K6806_12790	COG1840	ABC-type Fe3 transport system, periplasmic component
K6806_12795	COG0004	ammonium transporteR
K6806_12805	COG3112	Uncharacterised protein family (UPF0231)
K6806_12810	COG1049	propionate catabolic process, 2-methylcitrate cycle
K6806_12815	COG1752	Esterase of the alpha-beta hydrolase superfamily
K6806_12820	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
K6806_12825	COG1643	Atp-dependent helicase
K6806_12830	COG1489	DNA binding
K6806_12840	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
K6806_12850	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
K6806_12855	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
K6806_12860	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
K6806_12865	COG1560	Kdo2-lipid A biosynthetic process
K6806_12870	COG0842	Transport permease protein
K6806_12875	COG1131	(ABC) transporter
K6806_12880	COG0659	secondary active sulfate transmembrane transporter activity
K6806_12885	COG0288	reversible hydration of carbon dioxide
K6806_12900	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
K6806_12905	COG0508	dehydrogenase complex catalyzes the overall conversion of
K6806_12910	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
K6806_12915	COG2186	Transcriptional regulator
K6806_12925	COG0157	Belongs to the NadC ModD family
K6806_12935	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
K6806_12940	COG1459	type II secretion system
K6806_12950	COG0237	dephospho-CoA kinase activity
K6806_12955	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
K6806_12960	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
K6806_12975	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
K6806_12980	COG0228	four-way junction DNA binding
K6806_12985	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
K6806_12990	COG4137	Cytochrome C assembly protein
K6806_12995	COG4536	flavin adenine dinucleotide binding
K6806_13000	COG1854	S-ribosylhomocysteine lyase activity
K6806_13015	COG0612	Peptidase, M16
K6806_13020	COG1238	metal cluster binding
K6806_13030	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
K6806_13035	COG5016	pyruvate
K6806_13035	COG0511	ligase activity, forming carbon-carbon bonds
K6806_13040	COG3630	sodium ion export across plasma membrane
K6806_13105	COG0527	aspartate kinase activity
K6806_13110	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
K6806_13115	COG2137	regulation of response to DNA damage stimulus
K6806_13120	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
K6806_13125	COG1546	Belongs to the CinA family
K6806_13130	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
K6806_13135	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
K6806_13145	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
K6806_13150	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
K6806_13160	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
K6806_13165	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
K6806_13170	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
K6806_13175	COG0148	phosphopyruvate hydratase activity
K6806_13180	COG0504	CTP synthase activity
K6806_13185	COG3956	TIGRFAM MazG family protein
K6806_13190	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
K6806_13195	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
K6806_13205	COG0736	holo-[acyl-carrier-protein] synthase activity
K6806_13210	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
K6806_13215	COG1381	Involved in DNA repair and RecF pathway recombination
K6806_13220	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
K6806_13230	COG0681	Belongs to the peptidase S26 family
K6806_13235	COG0481	GTPase activity
K6806_13240	COG3086	response to oxidative stress
K6806_13255	COG1595	DNA-templated transcription, initiation
K6806_13260	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
K6806_13270	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
K6806_13290	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
K6806_13295	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
K6806_13300	COG3079	Belongs to the UPF0149 family
K6806_13305	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
K6806_13315	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
K6806_13320	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
K6806_13325	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
K6806_13335	COG0583	DNA-binding transcription factor activity
K6806_13350	COG0668	transmembrane transport
K6806_13355	COG0191	fructose-bisphosphate aldolase activity
K6806_13370	COG4771	TonB-dependent receptor
K6806_13375	COG0583	DNA-binding transcription factor activity
K6806_13380	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
K6806_13385	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
K6806_13400	COG2356	endonuclease I
K6806_13405	COG1385	rRNA (uridine-N3-)-methyltransferase activity
K6806_13410	COG0189	ligase activity
K6806_13415	COG1678	Uncharacterized ACR, COG1678
K6806_13420	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
K6806_13435	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
K6806_13440	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
K6806_13445	COG0762	integral membrane protein
K6806_13450	COG1872	DUF167
K6806_13460	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
K6806_13465	COG0635	Involved in the biosynthesis of porphyrin-containing compound
K6806_13470	COG2066	Belongs to the glutaminase family
K6806_13480	COG0220	tRNA (guanine-N7-)-methyltransferase activity
K6806_13490	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
K6806_13535	COG0840	transmembrane signaling receptor activity
K6806_13610	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
K6806_13615	COG1609	Transcriptional regulator
K6806_13620	COG3394	polysaccharide catabolic process
K6806_13625	COG1486	melibiose metabolic process
K6806_13630	COG1447	Phosphotransferase system cellobiose-specific component IIA
K6806_13635	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
K6806_13640	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
K6806_13645	COG0726	polysaccharide deacetylase
K6806_13655	COG1028	Short-chain dehydrogenase reductase Sdr
K6806_13670	COG0795	lipopolysaccharide-transporting ATPase activity
K6806_13675	COG0795	lipopolysaccharide-transporting ATPase activity
K6806_13680	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
K6806_13685	COG2927	DNA polymerase III (CHI subunit)
K6806_13690	COG0525	valine-tRNA ligase activity
K6806_13700	COG0456	acetyltransferase
K6806_13730	COG0540	Belongs to the ATCase OTCase family
K6806_13735	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
K6806_13740	COG0251	oxidation-reduction process
K6806_13745	COG0204	Acyl-transferase
K6806_13750	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
K6806_13755	COG5007	Belongs to the BolA IbaG family
K6806_13765	COG2854	intermembrane phospholipid transfer
K6806_13770	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
K6806_13775	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
K6806_13780	COG1127	ABC transporter
K6806_13790	COG0517	IMP dehydrogenase activity
K6806_13790	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
K6806_13800	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
K6806_13805	COG1137	ATPase activity
K6806_13815	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
K6806_13820	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
K6806_13825	COG1660	Displays ATPase and GTPase activities
K6806_13830	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
K6806_13835	COG2239	Acts as a magnesium transporter
K6806_13840	COG0312	modulator of DNA gyrase
K6806_13845	COG3028	Belongs to the UPF0307 family
K6806_13850	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
K6806_13855	COG0564	pseudouridine synthase activity
K6806_13865	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
K6806_13870	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
K6806_13875	COG0312	modulator of DNA gyrase
K6806_13880	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
K6806_13885	COG3164	Protein of unknown function
K6806_13895	COG0424	maF-like protein
K6806_13900	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
K6806_13905	COG1792	Involved in formation and maintenance of cell shape
K6806_13910	COG1077	Cell shape determining protein MreB Mrl
K6806_13945	COG2165	general secretion pathway protein
K6806_13955	COG1459	type II secretion system
K6806_13960	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
K6806_13970	COG3267	Type II secretory pathway component ExeA
K6806_13970	COG3409	Peptidoglycan-binding domain 1 protein
K6806_13975	COG1450	Type ii and iii secretion system protein
K6806_13995	COG2199	diguanylate cyclase activity
K6806_13995	COG2200	EAL domain
K6806_14000	COG0629	single-stranded DNA binding
K6806_14015	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
K6806_14025	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
K6806_14030	COG0527	aspartate kinase activity
K6806_14035	COG0646	methionine synthase
K6806_14035	COG1410	methionine synthase
K6806_14095	COG0175	sulfate reduction
K6806_14100	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
K6806_14105	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
K6806_14125	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
K6806_14130	COG0735	belongs to the Fur family
K6806_14140	COG0166	Belongs to the GPI family
K6806_14145	COG0432	Pfam Uncharacterised protein family UPF0047
K6806_14150	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
K6806_14175	COG2965	DNA replication, synthesis of RNA primer
K6806_14180	COG0360	Binds together with S18 to 16S ribosomal RNA
K6806_14185	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
K6806_14190	COG0338	D12 class N6 adenine-specific DNA methyltransferase
K6806_14200	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
K6806_14205	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
K6806_14235	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
K6806_14245	COG0678	peroxiredoxin activity
K6806_14245	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
K6806_14250	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
K6806_14260	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
K6806_14260	COG0165	Argininosuccinate lyase
K6806_14265	COG0137	argininosuccinate synthase activity
K6806_14275	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
K6806_14285	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
K6806_14295	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
K6806_14300	COG0460	homoserine dehydrogenase
K6806_14300	COG0527	aspartate kinase activity
K6806_14305	COG0626	cystathionine gamma-synthase activity
K6806_14310	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
K6806_14315	COG0281	malic enzyme
K6806_14330	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
K6806_14335	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
K6806_14355	COG2923	Belongs to the DsrF TusC family
K6806_14360	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
K6806_14365	COG2964	Protein conserved in bacteria
K6806_14370	COG0545	Peptidyl-prolyl cis-trans isomerase
K6806_14385	COG1446	asparaginase
K6806_14390	COG1047	Peptidyl-prolyl cis-trans
K6806_14405	COG2249	NAD(P)H dehydrogenase (quinone) activity
K6806_14410	COG0488	(ABC) transporter
K6806_14420	COG0429	hydrolase of the alpha beta-hydrolase fold
K6806_14430	COG3954	Phosphoribulokinase
K6806_14435	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
K6806_14455	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
K6806_14460	COG0512	Glutamine amidotransferase of anthranilate synthase
K6806_14475	COG0180	Tryptophanyl-tRNA synthetase
K6806_14480	COG0546	phosphoglycolate phosphatase activity
K6806_14485	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
K6806_14490	COG0557	exoribonuclease II activity
K6806_14495	COG1959	2 iron, 2 sulfur cluster binding
K6806_14500	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
K6806_14500	COG1017	nitric oxide dioxygenase activity
K6806_14505	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
K6806_14510	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
K6806_14515	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
K6806_14520	COG0330	HflC and HflK could
K6806_14525	COG0330	HflC and HflK could
K6806_14530	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
K6806_14540	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
K6806_14545	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
K6806_14555	COG0802	atpase or kinase
K6806_14560	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
K6806_14620	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
K6806_14625	COG1162	GTPase activity
K6806_14630	COG0688	phosphatidylethanolamine metabolic process
K6806_14635	COG3273	potassium ion transport
K6806_14635	COG0471	metal ion transport
K6806_14645	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
K6806_14650	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
K6806_14655	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
K6806_14660	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
K6806_14665	COG1045	serine acetyltransferase
K6806_14670	COG4942	peptidase
K6806_14690	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
K6806_14695	COG1053	succinate dehydrogenase
K6806_14700	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
K6806_14705	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
K6806_14710	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
K6806_14725	COG1509	lysine 2,3-aminomutase activity
K6806_14730	COG1285	pathogenesis
K6806_14740	COG0459	protein refolding
K6806_14750	COG0534	Mate efflux family protein
K6806_14755	COG0205	6-phosphofructokinase activity
K6806_14765	COG3678	ATP-independent chaperone mediated protein folding
K6806_14770	COG0745	RESPONSE REGULATOR receiver
K6806_14775	COG2205	protein histidine kinase activity
K6806_14785	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
K6806_14790	COG3030	protein affecting phage T7 exclusion by the F plasmid
K6806_14795	COG1027	Aspartate ammonia-lyase
K6806_14800	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
K6806_14805	COG4232	protein-disulfide reductase activity
K6806_14815	COG3263	regulation of cellular component size
K6806_14825	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
K6806_14850	COG2814	Major facilitator Superfamily
K6806_14865	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
K6806_14870	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
K6806_14875	COG0511	ligase activity, forming carbon-carbon bonds
K6806_14880	COG0439	Biotin carboxylase
K6806_14885	COG2264	protein methyltransferase activity
K6806_14890	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
K6806_14895	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
K6806_14905	COG0488	(ABC) transporter
K6806_14955	COG1982	Orn Lys Arg decarboxylase major
K6806_14960	COG0531	amino acid
K6806_14965	COG3710	Transcriptional regulator
K6806_14970	COG0789	Transcriptional regulator
K6806_14980	COG0151	Belongs to the GarS family
K6806_14995	COG1253	flavin adenine dinucleotide binding
K6806_15000	COG3068	Protein conserved in bacteria
K6806_15010	COG1573	uracil-dna glycosylase
K6806_15015	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
K6806_15020	COG2816	NAD+ diphosphatase activity
K6806_15025	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
K6806_15030	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
K6806_15035	COG0085	RNA polymerase activity
K6806_15040	COG0222	ribosome binding
K6806_15045	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
K6806_15060	COG0250	Participates in transcription elongation, termination and antitermination
K6806_15065	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
K6806_15070	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
K6806_15100	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
K6806_15100	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
K6806_15105	COG0812	UDP-N-acetylmuramate dehydrogenase activity
K6806_15115	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
K6806_15190	COG4206	TonB-dependent receptor
K6806_15210	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
K6806_15215	COG0534	Mate efflux family protein
K6806_15220	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
K6806_15225	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
K6806_15230	COG2937	Belongs to the GPAT DAPAT family
K6806_15235	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
K6806_15240	COG3161	chorismate lyase activity
K6806_15245	COG1580	Controls the rotational direction of flagella during chemotaxis
K6806_15250	COG0705	Rhomboid family
K6806_15255	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
K6806_15265	COG2177	Part of the ABC transporter FtsEX involved in
K6806_15270	COG2884	Cell division ATP-binding protein ftsE
K6806_15275	COG0552	protein localization to endoplasmic reticulum
K6806_15280	COG0742	ribosomal rna small subunit methyltransferase
K6806_15290	COG2095	MarC family integral membrane protein
K6806_15335	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
K6806_15340	COG0640	Transcriptional regulator
K6806_15345	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
K6806_15350	COG1280	lysine exporter protein (LysE YggA)
K6806_15355	COG2267	carboxylic ester hydrolase activity
K6806_15360	COG0561	phosphatase activity
K6806_15375	COG3148	PFAM DTW domain containing protein
K6806_15380	COG3287	FIST C domain
K6806_15380	COG2199	diguanylate cyclase activity
K6806_15380	COG2200	EAL domain
K6806_15385	COG1011	Hydrolase
K6806_15390	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
K6806_15405	COG0019	diaminopimelate decarboxylase activity
K6806_15415	COG1965	Belongs to the frataxin family
K6806_15420	COG3072	Adenylate cyclase
K6806_15425	COG0181	hydroxymethylbilane synthase activity
K6806_15430	COG1587	Uroporphyrinogen-III synthase
K6806_15435	COG2959	enzyme of heme biosynthesis
K6806_15440	COG3071	HemY protein
K6806_15480	COG0633	Ferredoxin
K6806_15485	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
K6806_15500	COG3118	belongs to the thioredoxin family
K6806_15505	COG0513	Belongs to the DEAD box helicase family
K6806_15510	COG0248	Ppx GppA phosphatase
K6806_15520	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
K6806_15530	COG0514	ATP-dependent DNA helicase (RecQ)
K6806_15535	COG2962	Rard protein
K6806_15545	COG1280	lysine exporter protein (LysE YggA)
K6806_15550	COG0405	Gamma-glutamyltransferase
K6806_15555	COG0210	DNA helicase
K6806_15565	COG3220	belongs to the UPF0276 family
K6806_15595	COG0006	proline dipeptidase activity
K6806_15595	COG0006	proline dipeptidase activity
K6806_15615	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
K6806_15635	COG2132	Multicopper oxidase
K6806_15680	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
K6806_15695	COG0408	coproporphyrinogen oxidase activity
K6806_15700	COG0009	L-threonylcarbamoyladenylate synthase
K6806_15705	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
K6806_15710	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
K6806_15715	COG0551	DNA topoisomerase type I activity
K6806_15720	COG2922	Belongs to the Smg family
K6806_15725	COG0758	DNA mediated transformation
K6806_15735	COG0242	peptide deformylase activity
K6806_15740	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
K6806_15745	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
K6806_15745	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
K6806_15750	COG0569	domain protein
K6806_15755	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
K6806_15765	COG1272	protein, Hemolysin III
K6806_15770	COG4326	sporulation control protein
K6806_15780	COG3084	Protein conserved in bacteria
K6806_15790	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
K6806_15795	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
K6806_15800	COG0204	Acyl-transferase
K6806_15810	COG0606	chelatase, subunit chli
K6806_15820	COG3978	acetolactate synthase activity
K6806_15825	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
K6806_15830	COG0129	dihydroxy-acid dehydratase activity
K6806_15840	COG0583	DNA-binding transcription factor activity
K6806_15845	COG2814	Major facilitator Superfamily
K6806_15855	COG0765	amino acid transport
K6806_15865	COG0355	proton-transporting ATP synthase activity, rotational mechanism
K6806_15870	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
K6806_15875	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
K6806_15880	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
K6806_15885	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
K6806_15890	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
K6806_15900	COG0356	it plays a direct role in the translocation of protons across the membrane
K6806_15905	COG3312	ion transport
K6806_15910	COG1475	DNA binding
K6806_15915	COG1192	Involved in chromosome partitioning
K6806_15920	COG0357	Ribosomal RNA small subunit methyltransferase G
K6806_15925	COG0445	tRNA wobble uridine modification
K6806_15930	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
K6806_15940	COG0706	membrane insertase activity
K6806_15950	COG0594	ribonuclease P activity
K6806_15960	COG1126	abc transporter atp-binding protein
K6806_15980	COG2425	protein containing a von Willebrand factor type A (vWA) domain
K6806_15995	COG0583	DNA-binding transcription factor activity
K6806_16000	COG0277	FAD linked oxidase domain protein
K6806_16015	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
K6806_16065	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
K6806_16085	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
K6806_16090	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
K6806_16100	COG2116	formate transmembrane transporter activity
K6806_16120	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
K6806_16155	COG3118	belongs to the thioredoxin family
K6806_16160	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
K6806_16185	COG2271	Major facilitator Superfamily
K6806_16190	COG3851	Histidine kinase
K6806_16195	COG2197	response regulator
K6806_16205	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
K6806_16210	COG0583	DNA-binding transcription factor activity
K6806_16215	COG0243	molybdopterin cofactor binding
K6806_16230	COG0384	phenazine biosynthesis protein PhzF
K6806_16235	COG1794	racemase activity, acting on amino acids and derivatives
K6806_16240	COG0446	pyridine nucleotide-disulphide oxidoreductase
K6806_16280	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
K6806_16290	COG2207	Transcriptional regulator
K6806_16295	COG1979	alcohol dehydrogenase
K6806_16300	COG2801	Transposase and inactivated derivatives
K6806_16310	COG2814	Major facilitator Superfamily
K6806_16315	COG0583	DNA-binding transcription factor activity
K6806_16320	COG1902	pentaerythritol trinitrate reductase activity
K6806_16325	COG1902	pentaerythritol trinitrate reductase activity
K6806_16330	COG0604	alcohol dehydrogenase
K6806_16345	COG2249	NAD(P)H dehydrogenase (quinone) activity
K6806_16475	COG0384	phenazine biosynthesis protein PhzF
K6806_16500	COG1570	exodeoxyribonuclease VII activity
K6806_16560	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
K6806_16565	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
K6806_16575	COG0583	DNA-binding transcription factor activity
K6806_16580	COG1064	alcohol dehydrogenase
K6806_16585	COG1012	belongs to the aldehyde dehydrogenase family
K6806_16645	COG1328	CTP reductase activity
K6806_16650	COG0602	queuosine metabolic process
K6806_16655	COG0534	Mate efflux family protein
K6806_16660	COG2207	Transcriptional regulator
K6806_16670	COG0189	ligase activity
K6806_16670	COG4067	protein conserved in archaea
K6806_16680	COG3111	PFAM Bacterial OB fold (BOF) protein
K6806_16690	COG0725	ABC transporter, periplasmic molybdate-binding protein
K6806_16695	COG4149	molybdate abc transporter
K6806_16700	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
K6806_16710	COG5001	Diguanylate cyclase
K6806_16710	COG2203	Gaf domain
K6806_16710	COG3706	GGDEF domain
K6806_16710	COG4251	negative regulation of phosphorylation
K6806_16730	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
K6806_16735	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
K6806_16760	COG3140	Belongs to the UPF0181 family
K6806_16775	COG0583	DNA-binding transcription factor activity
K6806_16780	COG0023	Translation Initiation Factor
K6806_16790	COG1181	Belongs to the D-alanine--D-alanine ligase family
K6806_16800	COG0045	succinate-CoA ligase (ADP-forming) activity
K6806_16800	COG1042	CoA-binding domain protein
K6806_16800	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K6806_16805	COG0583	DNA-binding transcription factor activity
K6806_16820	COG5002	protein histidine kinase activity
K6806_16820	COG3447	MASE1 domain protein
K6806_16820	COG5001	Diguanylate cyclase
K6806_16825	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
K6806_16830	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
K6806_16835	COG1984	allophanate hydrolase subunit 2
K6806_16845	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
K6806_16850	COG4181	ATPase activity
K6806_16860	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
K6806_16865	COG3300	MHYT domain
K6806_16865	COG5001	Diguanylate cyclase
K6806_16900	COG4533	DNA binding
K6806_16910	COG2050	protein possibly involved in aromatic compounds catabolism
K6806_16925	COG2067	long-chain fatty acid transport protein
K6806_16930	COG2267	carboxylic ester hydrolase activity
K6806_16950	COG0861	Integral membrane protein TerC family
K6806_16955	COG0737	Belongs to the 5'-nucleotidase family
K6806_16960	COG3593	DNA synthesis involved in DNA repair
K6806_16970	COG0583	DNA-binding transcription factor activity
K6806_16975	COG2116	formate transmembrane transporter activity
K6806_16980	COG2353	YceI-like domain
K6806_16985	COG3038	cytochrome b561
K6806_17005	COG0513	Belongs to the DEAD box helicase family
K6806_17020	COG0840	transmembrane signaling receptor activity
K6806_17025	COG0546	phosphoglycolate phosphatase activity
K6806_17040	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
K6806_17045	COG2759	Belongs to the formate--tetrahydrofolate ligase family
K6806_17050	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
K6806_17060	COG2207	Transcriptional regulator
K6806_17065	COG1979	alcohol dehydrogenase
K6806_17075	COG1126	abc transporter atp-binding protein
K6806_17080	COG0765	amino acid transport
K6806_17085	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
K6806_17090	COG0765	amino acid transport
K6806_17095	COG2203	Gaf domain
K6806_17095	COG2200	EAL domain
K6806_17095	COG2199	diguanylate cyclase activity
K6806_17110	COG1609	Transcriptional regulator
K6806_17115	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
K6806_17115	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
K6806_17120	COG1105	Belongs to the carbohydrate kinase PfkB family
K6806_17125	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
K6806_17125	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
K6806_17125	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
K6806_17155	COG0404	The glycine cleavage system catalyzes the degradation of glycine
K6806_17165	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
K6806_17170	COG0509	glycine decarboxylation via glycine cleavage system
K6806_17180	COG0346	lactoylglutathione lyase activity
K6806_17185	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K6806_17190	COG0583	DNA-binding transcription factor activity
K6806_17195	COG0697	spore germination
K6806_17200	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
K6806_17255	COG2176	DNA-directed DNA polymerase activity
K6806_17300	COG0242	peptide deformylase activity
K6806_17325	COG2239	Acts as a magnesium transporter
K6806_17345	COG0346	lactoylglutathione lyase activity
K6806_17350	COG1902	pentaerythritol trinitrate reductase activity
K6806_17360	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
K6806_17360	COG2755	lipolytic protein G-D-S-L family
K6806_17370	COG5642	Protein of unknown function (DUF2384)
K6806_17375	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
K6806_17410	COG2076	Multidrug Resistance protein
K6806_17430	COG2962	Rard protein
K6806_17445	COG0784	Response regulator, receiver
K6806_17445	COG0835	chemotaxis
K6806_17450	COG2197	response regulator
K6806_17460	COG3706	GGDEF domain
K6806_17465	COG2197	response regulator
K6806_17470	COG3300	MHYT domain
K6806_17470	COG5001	Diguanylate cyclase
K6806_17480	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
K6806_17500	COG0456	acetyltransferase
K6806_17500	COG1214	PFAM Peptidase M22, glycoprotease
K6806_17510	COG3069	C4-dicarboxylate transmembrane transporter activity
K6806_17535	COG3111	PFAM Bacterial OB fold (BOF) protein
K6806_17540	COG1597	lipid kinase activity
K6806_17545	COG0583	DNA-binding transcription factor activity
K6806_17550	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
K6806_17580	COG0714	Associated with various cellular activities
K6806_17585	COG0641	radical SAM
K6806_17590	COG3119	arylsulfatase activity
K6806_17600	COG3119	arylsulfatase activity
K6806_17605	COG0745	RESPONSE REGULATOR receiver
K6806_17620	COG2198	Histidine kinase
K6806_17620	COG2205	protein histidine kinase activity
K6806_17620	COG0784	Response regulator, receiver
K6806_17625	COG1879	ABC-type sugar transport system periplasmic component
K6806_17630	COG1803	Methylglyoxal synthase
K6806_17635	COG0210	DNA helicase
K6806_17640	COG1289	transmembrane transporter activity
K6806_17670	COG1629	transport
K6806_17670	COG4771	TonB-dependent receptor
K6806_17680	COG0789	Transcriptional regulator
K6806_17685	COG4604	ABC transporter, ATP-binding protein
K6806_17690	COG4605	iron ion homeostasis
K6806_17695	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K6806_17700	COG4607	ABC-type enterochelin transport system periplasmic component
K6806_17710	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
K6806_17720	COG1609	Transcriptional regulator
K6806_17725	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
K6806_17730	COG1879	ABC-type sugar transport system periplasmic component
K6806_17735	COG1172	Belongs to the binding-protein-dependent transport system permease family
K6806_17740	COG1129	ABC transporter
K6806_17745	COG1869	D-ribose catabolic process
K6806_17750	COG5001	Diguanylate cyclase
K6806_17805	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
K6806_17815	COG0784	Response regulator, receiver
K6806_17815	COG2205	protein histidine kinase activity
K6806_17820	COG1858	cytochrome C peroxidase
K6806_17830	COG0330	HflC and HflK could
K6806_17845	COG4175	Glycine betaine
K6806_17845	COG0517	IMP dehydrogenase activity
K6806_17850	COG4176	ABC-type proline glycine betaine transport system permease component
K6806_17865	COG1012	belongs to the aldehyde dehydrogenase family
K6806_17870	COG1309	transcriptional regulator
K6806_17880	COG1028	Short-chain dehydrogenase reductase Sdr
K6806_17895	COG1024	Enoyl-CoA hydratase
K6806_17900	COG1960	acyl-CoA dehydrogenase activity
K6806_17910	COG0183	Belongs to the thiolase family
K6806_17920	COG1960	acyl-CoA dehydrogenase activity
K6806_17925	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
K6806_17935	COG4770	biotin carboxylase activity
K6806_17950	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
K6806_17950	COG3264	Mechanosensitive ion channel
K6806_17955	COG0110	maltose O-acetyltransferase activity
K6806_17960	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K6806_17965	COG1271	oxidase subunit
K6806_17970	COG1294	oxidase, subunit
K6806_17980	COG0384	phenazine biosynthesis protein PhzF
K6806_18000	COG3527	Alpha-acetolactate decarboxylase
K6806_18015	COG0500	methyltransferase
K6806_18045	COG1022	Amp-dependent synthetase and ligase
K6806_18070	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
K6806_18075	COG1263	PTS System
K6806_18075	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
K6806_18080	COG1486	melibiose metabolic process
K6806_18085	COG2188	Transcriptional regulator
K6806_18090	COG1320	monovalent cation:proton antiporter activity
K6806_18095	COG2212	antiporter activity
K6806_18100	COG1863	multisubunit Na H antiporter MnhE subunit
K6806_18105	COG0651	ATP synthesis coupled electron transport
K6806_18110	COG1006	Multisubunit Na H antiporter MnhC subunit
K6806_18115	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
K6806_18115	COG2111	Na H antiporter
K6806_18125	COG0589	response to stress
K6806_18130	COG4221	oxidoreductase activity
K6806_18135	COG0583	DNA-binding transcription factor activity
K6806_18145	COG2814	Major facilitator Superfamily
K6806_18210	COG1522	sequence-specific DNA binding
K6806_18245	COG0515	serine threonine protein kinase
K6806_18270	COG3501	Rhs element vgr protein
K6806_18310	COG0739	heme binding
K6806_18325	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K6806_18370	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
K6806_18380	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
K6806_18380	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
K6806_18395	COG4989	oxidoreductase activity
K6806_18410	COG0038	chloride channel
K6806_18445	COG2897	thiosulfate sulfurtransferase activity
K6806_18455	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
K6806_18460	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
K6806_18470	COG2814	Major facilitator Superfamily
K6806_18475	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
K6806_18485	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
K6806_18495	COG0840	transmembrane signaling receptor activity
K6806_18515	COG2195	Cleaves the N-terminal amino acid of tripeptides
K6806_18530	COG2197	response regulator
K6806_18535	COG3850	Histidine kinase
K6806_18540	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
K6806_18550	COG0243	molybdopterin cofactor binding
K6806_18560	COG3005	denitrification pathway
K6806_18570	COG3243	poly(R)-hydroxyalkanoic acid synthase
K6806_18580	COG0183	Belongs to the thiolase family
K6806_18590	COG1280	lysine exporter protein (LysE YggA)
K6806_18600	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
K6806_18605	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
K6806_18655	COG1846	Transcriptional regulator
K6806_18660	COG2205	protein histidine kinase activity
K6806_18660	COG0784	Response regulator, receiver
K6806_18665	COG1879	ABC-type sugar transport system periplasmic component
K6806_18670	COG2827	Endonuclease containing a URI domain
K6806_18675	COG3132	Protein of unknown function, DUF480
K6806_18695	COG2205	protein histidine kinase activity
K6806_18695	COG5002	protein histidine kinase activity
K6806_18695	COG0784	Response regulator, receiver
K6806_18720	COG0583	DNA-binding transcription factor activity
K6806_18730	COG0531	amino acid
K6806_18745	COG2205	protein histidine kinase activity
K6806_18750	COG0745	RESPONSE REGULATOR receiver
K6806_18775	COG1566	PFAM secretion protein HlyD family protein
K6806_18780	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
K6806_18785	COG2239	Acts as a magnesium transporter
K6806_18790	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
K6806_18795	COG0402	S-adenosylhomocysteine deaminase activity
K6806_18800	COG1418	mRNA catabolic process
K6806_18810	COG2814	Major facilitator Superfamily
K6806_18820	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
K6806_18840	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
K6806_18855	COG0745	RESPONSE REGULATOR receiver
K6806_18860	COG2205	protein histidine kinase activity
K6806_18870	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
K6806_18875	COG2194	sulfuric ester hydrolase activity
K6806_18895	COG4667	esterase of the alpha-beta hydrolase superfamily
K6806_18900	COG1741	Belongs to the pirin family
K6806_18905	COG1278	Cold shock
K6806_18920	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
K6806_18925	COG0678	peroxiredoxin activity
K6806_18925	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
K6806_18935	COG1686	Belongs to the peptidase S11 family
K6806_18940	COG0625	glutathione transferase activity
K6806_18945	COG1621	beta-fructofuranosidase activity
K6806_18950	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
K6806_18955	COG1263	PTS System
K6806_18955	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
K6806_18980	COG0583	DNA-binding transcription factor activity
K6806_18990	COG1404	Belongs to the peptidase S8 family
K6806_18995	COG1028	Short-chain dehydrogenase reductase Sdr
K6806_19010	COG3746	phosphate-selective porin O and P
K6806_19025	COG0300	oxidoreductase activity
K6806_19030	COG0583	DNA-binding transcription factor activity
K6806_19035	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
K6806_19035	COG2207	Transcriptional regulator
K6806_19040	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K6806_19060	COG0513	Belongs to the DEAD box helicase family
K6806_19070	COG0583	DNA-binding transcription factor activity
K6806_19085	COG1902	pentaerythritol trinitrate reductase activity
K6806_19090	COG1063	alcohol dehydrogenase
K6806_19100	COG1028	Short-chain dehydrogenase reductase Sdr
K6806_19110	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K6806_19115	COG0006	proline dipeptidase activity
K6806_19120	COG3608	succinylglutamate desuccinylase aspartoacylase
K6806_19125	COG1522	sequence-specific DNA binding
K6806_19130	COG1012	belongs to the aldehyde dehydrogenase family
K6806_19135	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
K6806_19140	COG3122	Protein conserved in bacteria
K6806_19155	COG0583	DNA-binding transcription factor activity
K6806_19160	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
K6806_19165	COG0252	asparaginase activity
K6806_19170	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
K6806_19185	COG2197	response regulator
K6806_19190	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
K6806_19215	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
K6806_19245	COG3842	ATPase activity
K6806_19265	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
K6806_19295	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
K6806_19300	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
K6806_19330	COG0583	DNA-binding transcription factor activity
K6806_19340	COG4948	Mandelate Racemase Muconate Lactonizing
K6806_19370	COG1342	Belongs to the UPF0251 family
K6806_19375	COG4176	ABC-type proline glycine betaine transport system permease component
K6806_19380	COG3448	diguanylate cyclase activity
K6806_19380	COG4175	Glycine betaine
K6806_19385	COG3015	lipoprotein NlpE involved in copper resistance
K6806_19390	COG3713	MltA-interacting MipA family protein
K6806_19405	COG0583	DNA-binding transcription factor activity
K6806_19430	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
K6806_19440	COG1335	isochorismatase
K6806_19455	COG1349	DNA-binding transcription factor activity
K6806_19460	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
K6806_19460	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
K6806_19465	COG2070	2-Nitropropane dioxygenase
K6806_19470	COG0531	amino acid
K6806_19475	COG4302	ethanolamine ammonia-lyase activity
K6806_19480	COG4303	Ethanolamine ammonia lyase large subunit
K6806_19490	COG1309	transcriptional regulator
K6806_19520	COG0459	protein refolding
K6806_19525	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
K6806_19530	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
K6806_19545	COG1304	FMN binding
K6806_19570	COG1256	bacterial-type flagellum assembly
K6806_19570	COG4786	Flagellar basal body rod
K6806_19580	COG1706	bacterial-type flagellum-dependent cell motility
K6806_19585	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
K6806_19590	COG4786	Flagellar basal body rod
K6806_19595	COG4787	bacterial-type flagellum-dependent cell motility
K6806_19610	COG1558	bacterial-type flagellum-dependent cell motility
K6806_19615	COG1815	bacterial-type flagellum-dependent cell motility
K6806_19635	COG0741	lytic transglycosylase activity
K6806_19640	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
K6806_19660	COG1760	l-serine dehydratase
K6806_19675	COG0583	DNA-binding transcription factor activity
K6806_19685	COG2866	Carboxypeptidase
K6806_19690	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
K6806_19700	COG2990	Protein conserved in bacteria
K6806_19725	COG3842	ATPase activity
K6806_19730	COG1840	ABC-type Fe3 transport system, periplasmic component
K6806_19740	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
K6806_19750	COG1609	Transcriptional regulator
K6806_19780	COG3240	lipase activity
K6806_19785	COG1309	transcriptional regulator
K6806_19800	COG1136	(ABC) transporter
K6806_19800	COG0577	efflux transmembrane transporter activity
K6806_19805	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
K6806_19810	COG2067	long-chain fatty acid transport protein
K6806_19820	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
K6806_19835	COG1011	Hydrolase
K6806_19875	COG0110	maltose O-acetyltransferase activity
K6806_19880	COG1765	OsmC-like protein
K6806_19885	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
K6806_19885	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
K6806_19900	COG3046	protein related to deoxyribodipyrimidine photolyase
K6806_19905	COG0415	Belongs to the DNA photolyase family
K6806_19910	COG3706	GGDEF domain
K6806_19940	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
K6806_19960	COG3033	Beta-eliminating lyase
K6806_19970	COG1271	oxidase subunit
K6806_19975	COG1294	oxidase, subunit
K6806_19985	COG0579	oxidoreductase
K6806_20005	COG3706	GGDEF domain
K6806_20035	COG0583	DNA-binding transcription factor activity
K6806_20055	COG0189	ligase activity
K6806_20060	COG0189	ligase activity
K6806_20060	COG4067	protein conserved in archaea
K6806_20070	COG1166	arginine decarboxylase activity
K6806_20075	COG0010	Belongs to the arginase family
K6806_20080	COG2814	Major facilitator Superfamily
K6806_20085	COG1770	oligopeptidase
K6806_20100	COG1108	ABC-type Mn2 Zn2 transport systems permease components
K6806_20105	COG1121	(ABC) transporter
K6806_20110	COG0803	Belongs to the bacterial solute-binding protein 9 family
K6806_20150	COG0848	biopolymer transport protein
K6806_20155	COG0811	peptide transport
K6806_20160	COG0811	peptide transport
K6806_20180	COG0745	RESPONSE REGULATOR receiver
K6806_20185	COG0584	glycerophosphoryl diester phosphodiesterase
K6806_20195	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
K6806_20255	COG1901	pseudouridine methyltransferase
K6806_20260	COG0312	modulator of DNA gyrase
K6806_20265	COG0312	modulator of DNA gyrase
K6806_20270	COG0351	phosphomethylpyrimidine kinase
K6806_20275	COG1116	anion transmembrane transporter activity
K6806_20280	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
K6806_20285	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
K6806_20290	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
K6806_20310	COG0243	molybdopterin cofactor binding
K6806_20315	COG3005	denitrification pathway
K6806_20320	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K6806_20325	COG1028	Short-chain dehydrogenase reductase Sdr
K6806_20340	COG0456	acetyltransferase
K6806_20360	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K6806_20365	COG1929	Belongs to the glycerate kinase type-1 family
K6806_20370	COG2610	gluconate transmembrane transporter activity
K6806_20375	COG3835	regulator
K6806_20435	COG3047	cAMP biosynthetic process
K6806_20440	COG1357	PFAM Pentapeptide repeats (8 copies)
K6806_20470	COG2375	cellular response to nickel ion
K6806_20475	COG0583	DNA-binding transcription factor activity
K6806_20480	COG2162	N-hydroxyarylamine O-acetyltransferase activity
K6806_20485	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
K6806_20500	COG2199	diguanylate cyclase activity
K6806_20510	COG0561	phosphatase activity
K6806_20515	COG0583	DNA-binding transcription factor activity
K6806_20530	COG0564	pseudouridine synthase activity
K6806_20535	COG0534	Mate efflux family protein
K6806_20550	COG3123	guanosine phosphorylase activity
K6806_20565	COG0596	Alpha beta hydrolase
K6806_20590	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
K6806_20600	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
K6806_20605	COG2169	Transcriptional regulator
K6806_20605	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
K6806_20615	COG2259	Doxx family
K6806_20620	COG1741	Belongs to the pirin family
K6806_20640	COG0363	glucosamine-6-phosphate deaminase activity
K6806_20650	COG0786	glutamate:sodium symporter activity
K6806_20655	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K6806_20660	COG1131	(ABC) transporter
K6806_20670	COG0786	glutamate:sodium symporter activity
K6806_20690	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
K6806_20700	COG3279	Response regulator of the LytR AlgR family
K6806_20705	COG3275	phosphorelay sensor kinase activity
K6806_20725	COG1136	(ABC) transporter
K6806_20735	COG0772	Belongs to the SEDS family
K6806_20760	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
K6806_20760	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
K6806_20770	COG0444	Belongs to the ABC transporter superfamily
K6806_20775	COG4608	Belongs to the ABC transporter superfamily
K6806_20800	COG1444	tRNA N-acetyltransferase activity
K6806_20820	COG3340	Belongs to the peptidase S51 family
K6806_20825	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
K6806_20830	COG1263	PTS System
K6806_20830	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
K6806_20835	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
K6806_20850	COG4166	transmembrane transport
K6806_20900	COG0259	pyridoxamine-phosphate oxidase activity
K6806_20925	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
K6806_20960	COG1132	(ABC) transporter
K6806_20970	COG0513	Belongs to the DEAD box helicase family
K6806_20975	COG2258	MOSC domain
K6806_21020	COG3634	alkyl hydroperoxide reductase activity
K6806_21030	COG1846	Transcriptional regulator
K6806_21035	COG1764	response to oxidative stress
K6806_21070	COG0577	efflux transmembrane transporter activity
K6806_21075	COG1136	(ABC) transporter
K6806_21085	COG0826	peptidase U32
K6806_21110	COG1653	transport
K6806_21115	COG0019	diaminopimelate decarboxylase activity
K6806_21120	COG4264	IucA IucC family
K6806_21145	COG4772	TonB-dependent receptor
K6806_21150	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
K6806_21155	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K6806_21160	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K6806_21165	COG1120	ATPase activity
K6806_21170	COG0840	transmembrane signaling receptor activity
K6806_21175	COG0612	Peptidase, M16
K6806_21185	COG0739	heme binding
K6806_21200	COG2814	Major facilitator Superfamily
K6806_21210	COG1609	Transcriptional regulator
K6806_21215	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
K6806_21230	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
K6806_21230	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
K6806_21240	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
K6806_21245	COG1609	Transcriptional regulator
K6806_21255	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
K6806_21270	COG0596	Alpha beta hydrolase
K6806_21295	COG1760	l-serine dehydratase
K6806_21305	COG4580	involved in the transport of maltose and maltodextrins
K6806_21325	COG2356	endonuclease I
K6806_21345	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
K6806_21350	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
K6806_21355	COG1162	GTPase activity
K6806_21360	COG1263	PTS System
K6806_21360	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
K6806_21365	COG1999	signal sequence binding
K6806_21380	COG2909	trisaccharide binding
K6806_21385	COG0058	SHG alpha-glucan phosphorylase activity
K6806_21390	COG1640	4-alpha-glucanotransferase
K6806_21395	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
K6806_21400	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
K6806_21405	COG0366	Alpha amylase catalytic
K6806_21420	COG3366	ferrous iron transmembrane transporter activity
K6806_21425	COG0700	Nucleoside recognition
K6806_21430	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
K6806_21435	COG3339	Conserved Protein
K6806_21440	COG1301	dicarboxylic acid transport
K6806_21450	COG0583	DNA-binding transcription factor activity
K6806_21470	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
K6806_21475	COG1596	polysaccharide export
K6806_21490	COG2095	MarC family integral membrane protein
K6806_21495	COG4667	esterase of the alpha-beta hydrolase superfamily
K6806_21500	COG3397	chitin binding
K6806_21505	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
K6806_21510	COG0415	Belongs to the DNA photolyase family
K6806_21520	COG1054	Belongs to the UPF0176 family
K6806_21530	COG1686	Belongs to the peptidase S11 family
K6806_21555	COG0583	DNA-binding transcription factor activity
K6806_21560	COG4628	conserved protein (DUF2132)
K6806_21580	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
K6806_21585	COG0628	permease
K6806_21625	COG2814	Major facilitator Superfamily
K6806_21635	COG0454	-acetyltransferase
K6806_21645	COG0745	RESPONSE REGULATOR receiver
K6806_21650	COG2205	protein histidine kinase activity
K6806_21665	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
K6806_21670	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
K6806_21675	COG1882	Formate acetyltransferase
K6806_21705	COG1360	Flagellar Motor Protein
K6806_21710	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
K6806_21715	COG1191	sigma factor activity
K6806_21720	COG1580	Controls the rotational direction of flagella during chemotaxis
K6806_21735	COG1516	flagellar protein fliS
K6806_21740	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
K6806_21750	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
K6806_21765	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
K6806_21775	COG1987	bacterial-type flagellum assembly
K6806_21815	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
K6806_21875	COG0346	lactoylglutathione lyase activity
K6806_21900	COG0745	RESPONSE REGULATOR receiver
K6806_21925	COG3300	MHYT domain
K6806_21925	COG5001	Diguanylate cyclase
K6806_21930	COG0156	8-amino-7-oxononanoate synthase activity
K6806_21935	COG1063	alcohol dehydrogenase
K6806_21970	COG0668	transmembrane transport
K6806_21980	COG1304	FMN binding
K6806_21985	COG1620	l-lactate permease
K6806_21990	COG0583	DNA-binding transcription factor activity
K6806_21995	COG1505	serine-type exopeptidase activity
K6806_22000	COG4172	Belongs to the ABC transporter superfamily
K6806_22010	COG1067	ATP-dependent peptidase activity
K6806_22020	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
K6806_22040	COG1247	-acetyltransferase
K6806_22045	COG0437	4 iron, 4 sulfur cluster binding
K6806_22050	COG0348	domain, Protein
K6806_22070	COG1122	ATPase activity
K6806_22075	COG4720	Psort location CytoplasmicMembrane, score
K6806_22080	COG1566	PFAM secretion protein HlyD family protein
K6806_22105	COG0813	purine-nucleoside phosphorylase activity
K6806_22110	COG3272	Protein of unknown function (DUF1722)
K6806_22115	COG0789	Transcriptional regulator
K6806_22120	COG0415	Belongs to the DNA photolyase family
K6806_22125	COG1376	ErfK ybiS ycfS ynhG family protein
K6806_22125	COG1388	LysM domain
K6806_22135	COG0513	Belongs to the DEAD box helicase family
K6806_22140	COG1770	oligopeptidase
K6806_22145	COG4771	TonB-dependent receptor
K6806_22175	COG0573	inorganic phosphate transmembrane transporter activity
K6806_22180	COG0581	inorganic phosphate transmembrane transporter activity
K6806_22185	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
K6806_22200	COG2304	oxidoreductase activity
K6806_22220	COG0714	Associated with various cellular activities
K6806_22225	COG0840	transmembrane signaling receptor activity
K6806_22235	COG2197	response regulator
K6806_22270	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
K6806_22275	COG1120	ATPase activity
K6806_22280	COG4774	siderophore transport
K6806_22285	COG1132	(ABC) transporter
K6806_22290	COG2205	protein histidine kinase activity
K6806_22290	COG2205	protein histidine kinase activity
K6806_22295	COG0745	RESPONSE REGULATOR receiver
K6806_22300	COG0569	domain protein
K6806_22305	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
K6806_22310	COG0583	DNA-binding transcription factor activity
K6806_22325	COG1012	belongs to the aldehyde dehydrogenase family
K6806_22330	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
K6806_22335	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
K6806_22345	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
K6806_22350	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
K6806_22380	COG2084	Dehydrogenase
K6806_22385	COG0753	catalase activity
K6806_22395	COG2130	NADP-dependent
K6806_22400	COG1309	transcriptional regulator
K6806_22405	COG3097	Belongs to the UPF0267 family
K6806_22445	COG3206	protein involved in exopolysaccharide biosynthesis
K6806_22445	COG0489	protein tyrosine kinase activity
K6806_22460	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
K6806_22465	COG3842	ATPase activity
K6806_22475	COG1175	transmembrane transport
K6806_22480	COG3833	ABC-type maltose transport systems, permease component
K6806_22510	COG2375	cellular response to nickel ion
K6806_22510	COG1132	(ABC) transporter
K6806_22515	COG4774	siderophore transport
K6806_22520	COG4607	ABC-type enterochelin transport system periplasmic component
K6806_22525	COG4605	iron ion homeostasis
K6806_22530	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K6806_22540	COG2354	Protein conserved in bacteria
K6806_22545	COG0418	dihydroorotase activity
K6806_22550	COG0401	homolog of Blt101
K6806_22555	COG0633	Ferredoxin
K6806_22555	COG0633	Ferredoxin
K6806_22555	COG3217	Mosc domain protein beta barrel domain protein
K6806_22555	COG3217	Mosc domain protein beta barrel domain protein
K6806_22565	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
K6806_22605	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
K6806_22610	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K6806_22620	COG0848	biopolymer transport protein
K6806_22625	COG0811	peptide transport
K6806_22630	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
K6806_22640	COG3721	Heme iron utilization protein
K6806_22645	COG0748	coenzyme F420 binding
K6806_22655	COG0784	Response regulator, receiver
K6806_22655	COG0835	chemotaxis
K6806_22660	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
K6806_22665	COG0534	Mate efflux family protein
K6806_22670	COG0444	Belongs to the ABC transporter superfamily
K6806_22675	COG4608	Belongs to the ABC transporter superfamily
K6806_22680	COG0747	negative chemotaxis
K6806_22690	COG1349	DNA-binding transcription factor activity
K6806_22695	COG2084	Dehydrogenase
K6806_22700	COG3395	kinase activity
K6806_22705	COG0235	Class ii aldolase
K6806_22710	COG3622	Belongs to the hyi family
K6806_22715	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
K6806_22720	COG2610	gluconate transmembrane transporter activity
K6806_22740	COG0583	DNA-binding transcription factor activity
K6806_22745	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
K6806_22755	COG4934	collagen metabolic process
K6806_22765	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
K6806_22770	COG0789	Transcriptional regulator
K6806_22775	COG0366	Alpha amylase catalytic
K6806_22795	COG2249	NAD(P)H dehydrogenase (quinone) activity
K6806_22800	COG0589	response to stress
K6806_22805	COG0488	(ABC) transporter
K6806_22810	COG1505	serine-type exopeptidase activity
K6806_22820	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
K6806_22830	COG2067	long-chain fatty acid transport protein
K6806_22840	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K6806_22865	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
K6806_22885	COG3383	formate dehydrogenase (NAD+) activity
K6806_22895	COG0842	Transport permease protein
K6806_22900	COG1131	(ABC) transporter
K6806_22915	COG1881	PFAM PEBP family protein
K6806_22925	COG0798	PFAM Bile acid sodium symporter
K6806_22940	COG1733	regulation of RNA biosynthetic process
K6806_22965	COG4989	oxidoreductase activity
K6806_22990	COG0814	amino acid
K6806_23005	COG3314	Sporulation integral membrane protein YlbJ
K6806_23025	COG0739	heme binding
K6806_23030	COG5001	Diguanylate cyclase
K6806_23035	COG0583	DNA-binding transcription factor activity
K6806_23040	COG2814	Major facilitator Superfamily
K6806_23055	COG0697	spore germination
K6806_23060	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
K6806_23070	COG0179	Fumarylacetoacetate (FAA) hydrolase
K6806_23090	COG1280	lysine exporter protein (LysE YggA)
K6806_23100	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
K6806_23105	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
K6806_23110	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
K6806_23115	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
K6806_23120	COG1845	cytochrome c oxidase, subunit III
K6806_23140	COG1612	heme a metabolic process
K6806_23145	COG0109	protoheme IX farnesyltransferase activity
K6806_23150	COG0545	Peptidyl-prolyl cis-trans isomerase
K6806_23180	COG1278	Cold shock
K6806_23185	COG3036	rescue of stalled ribosome
K6806_23190	COG2199	diguanylate cyclase activity
K6806_23205	COG1132	(ABC) transporter
K6806_23215	COG1538	Outer membrane efflux protein
K6806_23220	COG0784	Response regulator, receiver
K6806_23220	COG2205	protein histidine kinase activity
K6806_23245	COG0840	transmembrane signaling receptor activity
K6806_23250	COG0783	Belongs to the Dps family
K6806_23260	COG2133	pyrroloquinoline quinone binding
K6806_23265	COG1454	alcohol dehydrogenase
K6806_23270	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
K6806_23295	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
K6806_23300	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
K6806_23305	COG3186	Phenylalanine-4-hydroxylase
K6806_23330	COG3530	Putative quorum-sensing-regulated virulence factor
K6806_23345	COG2814	Major facilitator Superfamily
K6806_23350	COG0513	Belongs to the DEAD box helicase family
K6806_23355	COG4628	conserved protein (DUF2132)
K6806_23365	COG0133	tryptophan synthase activity
K6806_23370	COG1278	Cold shock
K6806_23380	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
K6806_23390	COG0523	cobalamin synthesis protein
K6806_23395	COG0513	Belongs to the DEAD box helicase family
K6806_23415	COG2200	EAL domain
K6806_23420	COG1119	ATPase activity
K6806_23455	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
K6806_23460	COG0513	Belongs to the DEAD box helicase family
K6806_23470	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
K6806_23480	COG1073	alpha beta
K6806_23485	COG1073	alpha beta
K6806_23500	COG0730	response to heat
K6806_23515	COG0735	belongs to the Fur family
K6806_23520	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
K6806_23530	COG0523	cobalamin synthesis protein
K6806_23535	COG2988	succinylglutamate desuccinylase activity
K6806_23540	COG0739	heme binding
K6806_23545	COG0523	cobalamin synthesis protein
K6806_23560	COG2095	MarC family integral membrane protein
K6806_23590	COG1024	Enoyl-CoA hydratase
K6806_23595	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
K6806_23600	COG1960	acyl-CoA dehydrogenase activity
K6806_23610	COG0183	Belongs to the thiolase family
K6806_23625	COG1024	Enoyl-CoA hydratase
K6806_23630	COG1024	Enoyl-CoA hydratase
K6806_23640	COG1028	Short-chain dehydrogenase reductase Sdr
K6806_23645	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
K6806_23650	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
K6806_23655	COG1845	cytochrome c oxidase, subunit III
K6806_23660	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
K6806_23665	COG0109	protoheme IX farnesyltransferase activity
K6806_23670	COG0446	pyridine nucleotide-disulphide oxidoreductase
K6806_23670	COG1902	pentaerythritol trinitrate reductase activity
K6806_23685	COG1012	belongs to the aldehyde dehydrogenase family
K6806_23695	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
K6806_23725	COG1126	abc transporter atp-binding protein
K6806_23730	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
K6806_23735	COG4215	(ABC) transporter
K6806_23740	COG4160	amino acid transport
K6806_23810	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
K6806_23815	COG2176	DNA-directed DNA polymerase activity
K6806_23820	COG0517	IMP dehydrogenase activity
K6806_23825	COG2186	Transcriptional regulator
K6806_23830	COG2186	Transcriptional regulator
K6806_23845	COG2801	Transposase and inactivated derivatives
K6806_23880	COG1917	Cupin 2, conserved barrel domain protein
K6806_23885	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
K6806_23890	COG0800	Aldolase
K6806_23900	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
K6806_23905	COG1028	Short-chain dehydrogenase reductase Sdr
K6806_23910	COG2847	Copper chaperone PCu(A)C
K6806_23970	COG0814	amino acid
K6806_23980	COG0243	molybdopterin cofactor binding
K6806_24000	COG3707	response regulator
K6806_24005	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
K6806_24005	COG1116	anion transmembrane transporter activity
K6806_24010	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
K6806_24015	COG1116	anion transmembrane transporter activity
K6806_24020	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
K6806_24020	COG2146	nitrite reductase [NAD(P)H] activity
K6806_24065	COG0515	serine threonine protein kinase
K6806_24065	COG2815	serine threonine protein kinase
K6806_24100	COG0631	protein serine/threonine phosphatase activity
K6806_24170	COG0420	3'-5' exonuclease activity
K6806_24175	COG0419	ATPase involved in DNA repair
K6806_24185	COG3040	lipid binding
K6806_24195	COG1288	antiporter activity
K6806_24205	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
K6806_24240	COG1475	DNA binding
K6806_24245	COG1192	Involved in chromosome partitioning
K6806_24305	COG0629	single-stranded DNA binding
K6806_24360	COG0776	regulation of translation
K6806_24690	COG1462	curli production assembly transport component CsgG