locus-tag	class	description
VagYM4_00010	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
VagYM4_00020	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
VagYM4_00030	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
VagYM4_00040	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
VagYM4_00070	ENOG4108ZNX	Heat shock protein
VagYM4_00080	ENOG4105JKW	Valine--pyruvate aminotransferase
VagYM4_00090	ENOG4107T9C	Alpha amylase catalytic region
VagYM4_00100	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
VagYM4_00110	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
VagYM4_00140	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
VagYM4_00170	ENOG4105D3Z	quinone oxidoreductase, yhdh yhfp family
VagYM4_00180	ENOG4105CHU	acetyl-coa acetyltransferase
VagYM4_00190	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
VagYM4_00200	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
VagYM4_00210	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
VagYM4_00220	ENOG4108RR8	protoporphyrinogen oxidase
VagYM4_00230	ENOG4105EMY	transcriptional regulator
VagYM4_00250	ENOG4105W0Z	cytoplasmic protein
VagYM4_00260	ENOG4105BZS	acriflavin resistance protein
VagYM4_00270	ENOG410624X	efflux transporter, rnd family, mfp subunit
VagYM4_00280	ENOG41067SE	Tetr family transcriptional regulator
VagYM4_00290	ENOG4105C4R	Atp-dependent dna helicase
VagYM4_00300	ENOG4105MPD	Cytochrome
VagYM4_00330	ENOG4107QSI	ABC, transporter
VagYM4_00340	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
VagYM4_00350	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
VagYM4_00420	ENOG4105DIQ	Transcriptional regulator
VagYM4_00430	ENOG41064T2	transcriptional regulator, lysR family
VagYM4_00440	ENOG41090TI	Catalyzes the excretion of spermidine (By similarity)
VagYM4_00460	ENOG4105C01	Dihydroxy-acid dehydratase
VagYM4_00470	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
VagYM4_00480	ENOG4105C6Z	Gluconate
VagYM4_00490	ENOG4108UHU	Aldolase
VagYM4_00500	ENOG4107U5R	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity)
VagYM4_00510	ENOG4107RSM	transcriptional regulator
VagYM4_00520	ENOG4105DC8	reductase
VagYM4_00530	ENOG4105D6S	protein involved in catabolism of external DNA
VagYM4_00540	ENOG4105DGW	oligopeptidase A
VagYM4_00550	ENOG4108VVK	transcriptional Regulator, AsnC
VagYM4_00560	ENOG4105BZU	Histidine kinase
VagYM4_00570	ENOG4105FFN	Specifically methylates the guanosine in position 1516 of 16S rRNA (By similarity)
VagYM4_00590	ENOG4105EMK	carboxylate amino acid amine transporter
VagYM4_00600	ENOG4108M6U	Universal stress protein A
VagYM4_00610	ENOG41090A1	ferritin
VagYM4_00620	ENOG4108V6B	universal stress protein B
VagYM4_00630	ENOG4105CBX	hi0933 family
VagYM4_00640	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
VagYM4_00690	ENOG4107TE5	Lipid kinase
VagYM4_00750	ENOG4105DSF	transport protein
VagYM4_00760	ENOG4105BZU	Histidine kinase
VagYM4_00780	ENOG4105CGY	Dna recombination protein
VagYM4_00790	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
VagYM4_00800	ENOG4105JC1	sterol-binding domain protein
VagYM4_00810	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
VagYM4_00820	ENOG4105WKS	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
VagYM4_00840	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
VagYM4_00850	ENOG4105F8V	Hydrolase, tatD family
VagYM4_00860	ENOG4105D52	delta-aminolevulinic acid dehydratase
VagYM4_00870	ENOG4105KD7	acetyltransferase
VagYM4_00880	ENOG4105C2M	dna polymerase I
VagYM4_00890	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
VagYM4_00900	ENOG4106RE7	Cytochrome
VagYM4_00920	ENOG4105ZR3	A GTPase-activating protein (GAP) that modifies Der EngA GTPase function. May play a role in ribosome biogenesis (By similarity)
VagYM4_00930	ENOG4105XCT	Protein of unknown function (DUF2489)
VagYM4_00940	ENOG4105D4P	Coproporphyrinogen iii oxidase
VagYM4_00950	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
VagYM4_00960	ENOG4105BZU	Histidine kinase
VagYM4_00970	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
VagYM4_00980	ENOG4105CUX	Signal transduction histidine kinase
VagYM4_01000	ENOG4105C5F	glutamine synthetase
VagYM4_01010	ENOG4105CI3	gtp-binding protein typa
VagYM4_01040	ENOG4107S2Z	UPF0761 membrane protein
VagYM4_01050	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
VagYM4_01060	ENOG4105SUU	thioesterase domain
VagYM4_01080	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
VagYM4_01090	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
VagYM4_01100	ENOG4105VEJ	Heat shock protein
VagYM4_01110	ENOG4108XKW	General secretion pathway protein C
VagYM4_01130	ENOG4107QHF	type ii secretion system protein e
VagYM4_01140	ENOG4105D7Q	type ii secretion system
VagYM4_01150	ENOG4108VAU	general secretion pathway protein G
VagYM4_01160	ENOG4105VWV	general secretion pathway protein h
VagYM4_01170	ENOG4105X5Z	General secretion pathway protein I
VagYM4_01180	ENOG4108WWZ	General secretion pathway protein J
VagYM4_01190	ENOG4108RTD	type II secretion system protein K
VagYM4_01200	ENOG4108BY5	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins (By similarity)
VagYM4_01210	ENOG4105U1E	general secretion pathway protein M
VagYM4_01220	ENOG4105PIC	general secretion pathway protein N
VagYM4_01240	ENOG4107RK2	ADP-ribose diphosphatase NudE
VagYM4_01250	ENOG4107RUK	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins (By similarity)
VagYM4_01260	ENOG4105MJ2	Competence protein
VagYM4_01270	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
VagYM4_01290	ENOG4105BZM	domain protein
VagYM4_01310	ENOG4108RRZ	Transcription elongation factor GreB
VagYM4_01340	ENOG4105E0F	Histidine kinase
VagYM4_01350	ENOG4105C2W	permease
VagYM4_01360	ENOG4105CB5	ATP-dependent DNA helicase recG
VagYM4_01370	ENOG4105FE8	tRNA (Guanosine-2'-O-)-methyltransferase
VagYM4_01380	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
VagYM4_01390	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
VagYM4_01400	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
VagYM4_01430	ENOG4109015	Biopolymer transport protein exbD tolR
VagYM4_01480	ENOG4108I5X	binding-protein-dependent transport systems inner membrane Component
VagYM4_01490	ENOG4108IYQ	Binding-protein-dependent transport systems inner membrane component
VagYM4_01500	ENOG4107QRA	Extracellular solute-binding protein, family 5
VagYM4_01520	ENOG4108JQ7	(ABC) transporter
VagYM4_01540	ENOG4105DSJ	YicC domain protein
VagYM4_01550	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
VagYM4_01560	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
VagYM4_01570	ENOG4105D1S	lipid A biosynthesis
VagYM4_01580	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
VagYM4_01590	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
VagYM4_01600	ENOG4105C8Q	Methyl-accepting chemotaxis
VagYM4_01610	ENOG4105W5Q	DNA repair protein (RadC
VagYM4_01620	ENOG4105KDC	50s ribosomal protein l28
VagYM4_01650	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
VagYM4_01670	ENOG4108JMC	lipopolysaccharide core biosynthesis protein
VagYM4_01680	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
VagYM4_01700	ENOG4106WTF	Glycosyl transferase, family 2
VagYM4_01710	ENOG4105DKP	glycosyl transferase, family 9
VagYM4_01720	ENOG41080IJ	Diacylglycerol kinase
VagYM4_01730	ENOG4108W7E	Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position (By similarity)
VagYM4_01740	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
VagYM4_01750	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
VagYM4_01770	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
VagYM4_01800	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
VagYM4_01810	ENOG4107SE4	UDP-N-acetylglucosamine 2-epimerase
VagYM4_01820	ENOG4105D2T	synthase
VagYM4_01850	ENOG4105F0R	Cytidylyltransferase
VagYM4_01860	ENOG41066S7	Glycosyltransferase family 52
VagYM4_01870	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
VagYM4_01880	ENOG4105XA0	heptosyltransferase ii
VagYM4_01890	ENOG4105NWR	lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase
VagYM4_01900	ENOG4105CUI	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity)
VagYM4_01910	ENOG4105E3R	(LipO)protein
VagYM4_01930	ENOG4108MDC	(LipO)protein
VagYM4_01960	ENOG4105DAY	polysaccharide export protein
VagYM4_02050	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
VagYM4_02070	ENOG4105ESV	Glycosyl transferase, family 4
VagYM4_02080	ENOG4105CY0	Metallo-Beta-Lactamase
VagYM4_02090	ENOG4107QQG	Dehydrogenase
VagYM4_02140	ENOG4105D7W	serine acetyltransferase
VagYM4_02170	ENOG4105CGN	Glycosyl transferase (Group 1
VagYM4_02180	ENOG4105D3Q	Sugar transferase
VagYM4_02200	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
VagYM4_02240	ENOG4105CP7	Triose-phosphate isomerase
VagYM4_02290	ENOG4105CBT	Fructose-1,6-bisphosphatase
VagYM4_02300	ENOG41065UX	Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA (By similarity)
VagYM4_02310	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
VagYM4_02320	ENOG4105EIS	1,4-dihydroxy-2-naphthoate octaprenyltransferase
VagYM4_02330	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
VagYM4_02340	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
VagYM4_02370	ENOG4105ETE	Transcriptional regulator (LacI family
VagYM4_02380	ENOG4105C25	Primosomal protein n'
VagYM4_02390	ENOG4105VFB	Binds the 23S rRNA (By similarity)
VagYM4_02400	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
VagYM4_02410	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
VagYM4_02420	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
VagYM4_02430	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
VagYM4_02440	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
VagYM4_02450	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
VagYM4_02460	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
VagYM4_02470	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
VagYM4_02480	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
VagYM4_02490	ENOG41083MP	50s ribosomal protein l29
VagYM4_02500	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
VagYM4_02510	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
VagYM4_02520	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
VagYM4_02530	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
VagYM4_02540	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
VagYM4_02550	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
VagYM4_02560	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
VagYM4_02580	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
VagYM4_02590	ENOG4105VPB	50S ribosomal protein L30
VagYM4_02600	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
VagYM4_02610	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
VagYM4_02630	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
VagYM4_02640	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
VagYM4_02650	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
VagYM4_02660	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
VagYM4_02670	ENOG4108ZT0	50S ribosomal protein l17
VagYM4_02690	ENOG4108V1T	peptidylprolyl cis-trans isomerase
VagYM4_02710	ENOG4107YB6	acetyltransferase, (GNAT) family
VagYM4_02720	ENOG4105C1J	atp-dependent rna helicase
VagYM4_02740	ENOG4107RNS	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic
VagYM4_02750	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
VagYM4_02760	ENOG4105C11	sulfate adenylyltransferase), subunit 2
VagYM4_02770	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
VagYM4_02790	ENOG4108I67	Catalyzes the synthesis of activated sulfate (By similarity)
VagYM4_02840	ENOG4108I0Y	(ABC) transporter
VagYM4_02870	ENOG4108UUE	Transcriptional regulator
VagYM4_02880	ENOG41061GZ	Protein of unknown function (DUF1107)
VagYM4_02890	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
VagYM4_02900	ENOG4105CFU	surface antigen
VagYM4_02910	ENOG4105MA0	exported protein
VagYM4_02920	ENOG41066HZ	AIG2-like family
VagYM4_02940	ENOG4105F0N	pyrophosphate phospho-hydrolase
VagYM4_02950	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
VagYM4_02960	ENOG4105DFU	Cell wall formation (By similarity)
VagYM4_02970	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
VagYM4_02980	ENOG4105DP9	ABC transporter
VagYM4_02990	ENOG4106SMU	thiamine transporter membrane protein
VagYM4_03000	ENOG4107T0D	ABC, transporter
VagYM4_03010	ENOG4105CC0	LysR family Transcriptional regulator
VagYM4_03020	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
VagYM4_03050	ENOG4105H1G	trap transporter solute receptor taxi family
VagYM4_03060	ENOG410682Y	Regulates arginine biosynthesis genes (By similarity)
VagYM4_03070	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
VagYM4_03090	ENOG4105EAH	synthase
VagYM4_03100	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
VagYM4_03110	ENOG4105K46	50S ribosomal protein l27
VagYM4_03120	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
VagYM4_03130	ENOG4105DWK	Membrane
VagYM4_03160	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
VagYM4_03170	ENOG4105NWN	ApaG protein
VagYM4_03180	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
VagYM4_03190	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
VagYM4_03200	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
VagYM4_03210	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
VagYM4_03220	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
VagYM4_03240	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
VagYM4_03250	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
VagYM4_03260	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
VagYM4_03270	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
VagYM4_03310	ENOG41064T2	transcriptional regulator, lysR family
VagYM4_03320	ENOG4108IQE	Amp-dependent synthetase and ligase
VagYM4_03330	ENOG4105C7K	acetolactate synthase
VagYM4_03340	ENOG4108ZP8	Acetolactate synthase small subunit
VagYM4_03350	ENOG4105BZU	Histidine kinase
VagYM4_03370	ENOG4105CA9	Pyruvate kinase
VagYM4_03380	ENOG410804X	Transcriptional regulator
VagYM4_03390	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
VagYM4_03420	ENOG4105GR3	Histidine kinase
VagYM4_03440	ENOG4105CMT	Dihydroxyacetone kinase
VagYM4_03450	ENOG4108UTZ	Dihydroxyacetone kinase
VagYM4_03480	ENOG4105E61	Mannitol repressor protein
VagYM4_03490	ENOG4107SQ3	mannitol-1-phosphate 5-dehydrogenase
VagYM4_03500	ENOG4105CTS	PTS system mannitol-specific
VagYM4_03560	ENOG4105D01	(LipO)protein
VagYM4_03570	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
VagYM4_03580	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
VagYM4_03590	ENOG4105KTH	gatB Yqey
VagYM4_03600	ENOG4105VCC	30S ribosomal protein S21
VagYM4_03610	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
VagYM4_03620	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
VagYM4_03630	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
VagYM4_03640	ENOG4107ZVW	dihydroneopterin aldolase
VagYM4_03650	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
VagYM4_03660	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
VagYM4_03670	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
VagYM4_03700	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
VagYM4_03710	ENOG4106MWK	domain protein
VagYM4_03720	ENOG4105CJ3	phosphate transporter
VagYM4_03730	ENOG4107IX6	phosphate transport regulator
VagYM4_03740	ENOG4105I7R	Adenylate cyclase
VagYM4_03760	ENOG4105C8Q	Methyl-accepting chemotaxis
VagYM4_03770	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
VagYM4_03780	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
VagYM4_03790	ENOG4105DFG	type I secretion outer membrane protein
VagYM4_03800	ENOG41087AY	ADP-Ribose pyrophosphatase
VagYM4_03810	ENOG4108SX3	cytoplasmic protein
VagYM4_03820	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
VagYM4_03830	ENOG4105IPS	esterase
VagYM4_03840	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
VagYM4_03850	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
VagYM4_03860	ENOG4105C0H	protease
VagYM4_03870	ENOG4105C0H	protease
VagYM4_03880	ENOG4108W2Q	Cytochrome d ubiquinol oxidase subunit III
VagYM4_03890	ENOG4105D6Z	AFG1 family ATPase
VagYM4_03900	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
VagYM4_03910	ENOG4108UJD	30S ribosomal protein S9
VagYM4_03920	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
VagYM4_03930	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
VagYM4_03940	ENOG4105EIX	cytochrome c1
VagYM4_03950	ENOG4107MKT	Stringent starvation protein a
VagYM4_03960	ENOG4105KB2	stringent starvation protein b
VagYM4_03970	ENOG4105W4M	Transport-associated protein
VagYM4_03980	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
VagYM4_03990	ENOG41082RQ	UPF0102 protein
VagYM4_04010	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
VagYM4_04020	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
VagYM4_04030	ENOG41063Y6	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
VagYM4_04040	ENOG4105CJN	penicillin-binding protein
VagYM4_04050	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
VagYM4_04060	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
VagYM4_04070	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
VagYM4_04080	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
VagYM4_04100	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
VagYM4_04110	ENOG4105DFU	Cell wall formation (By similarity)
VagYM4_04120	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
VagYM4_04130	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
VagYM4_04140	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
VagYM4_04150	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
VagYM4_04170	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
VagYM4_04180	ENOG4105M6F	mutator MutT protein
VagYM4_04190	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
VagYM4_04210	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
VagYM4_04220	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
VagYM4_04250	ENOG4105EJ9	Membrane
VagYM4_04260	ENOG4105VP0	transcriptional regulator, lysR family
VagYM4_04270	ENOG4105EN6	Membrane
VagYM4_04280	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
VagYM4_04290	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
VagYM4_04300	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
VagYM4_04320	ENOG4105BZ8	glutamate synthase
VagYM4_04330	ENOG4105CBC	glutamate synthase
VagYM4_04360	ENOG4105N5T	Radical SAM Protein
VagYM4_04380	ENOG4105BZU	Histidine kinase
VagYM4_04400	ENOG41065U4	response regulator
VagYM4_04420	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
VagYM4_04450	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
VagYM4_04460	ENOG4105D98	threonine synthase
VagYM4_04480	ENOG4108VKA	Acts as a radical domain for damaged PFL and possibly other radical proteins (By similarity)
VagYM4_04490	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
VagYM4_04500	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
VagYM4_04530	ENOG4105BZG	amino acid carrier protein
VagYM4_04540	ENOG4105D1Q	UPF0246 protein
VagYM4_04550	ENOG4105C1J	atp-dependent rna helicase
VagYM4_04560	ENOG4107S47	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (By similarity)
VagYM4_04570	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
VagYM4_04580	ENOG41071R3	Low-potential electron donor to a number of redox enzymes (By similarity)
VagYM4_04600	ENOG4105T95	Thiol disulfide interChange protein
VagYM4_04610	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
VagYM4_04620	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
VagYM4_04630	ENOG4105CRK	lysyL-tRNA synthetase
VagYM4_04640	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
VagYM4_04670	ENOG4105CPC	Aldo Keto reductase
VagYM4_04690	ENOG4105IRT	Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair (By similarity)
VagYM4_04700	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
VagYM4_04710	ENOG4108HRM	phosphoenolpyruvate--protein phosphotransferase
VagYM4_04720	ENOG4105HF0	Membrane
VagYM4_04730	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
VagYM4_04740	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
VagYM4_04770	ENOG41063Z6	transcriptional regulator, lysR family
VagYM4_04780	ENOG41080HT	Transcriptional regulator, arsr family
VagYM4_04790	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
VagYM4_04800	ENOG4105CJR	Integral membrane protein (MviN
VagYM4_04810	ENOG4105DTN	riboflavin biosynthesis protein ribF
VagYM4_04820	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
VagYM4_04830	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
VagYM4_04840	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
VagYM4_04850	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
VagYM4_04890	ENOG4108NEV	two component transcriptional regulator, LytTR family
VagYM4_04900	ENOG4108HRK	Histidine kinase
VagYM4_04940	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
VagYM4_04950	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
VagYM4_04960	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
VagYM4_04970	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
VagYM4_04980	ENOG4105EHE	chorismate mutase- prephenate dehydrogenase
VagYM4_04990	ENOG4105E4C	Lytic transglycosylase catalytic
VagYM4_05010	ENOG4105C5H	ABC transporter
VagYM4_05020	ENOG4107SC1	transglycosylase
VagYM4_05030	ENOG4105R9M	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region (By similarity)
VagYM4_05040	ENOG4108K16	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
VagYM4_05060	ENOG4108WPH	sigma 54 modulation protein ribosomal protein S30EA
VagYM4_05070	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
VagYM4_05080	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
VagYM4_05090	ENOG4105C34	Pseudouridine synthase
VagYM4_05100	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
VagYM4_05110	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
VagYM4_05150	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
VagYM4_05160	ENOG4105CFP	Peptidase U32
VagYM4_05170	ENOG4105DH7	May be involved in recombination (By similarity)
VagYM4_05180	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
VagYM4_05190	ENOG4105BZU	Histidine kinase
VagYM4_05200	ENOG4105DJH	phosphate
VagYM4_05210	ENOG4105C9X	ppx gppa phosphatase
VagYM4_05220	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
VagYM4_05230	ENOG4105C8U	phosphate abc transporter
VagYM4_05240	ENOG4105E2Z	phosphate ABC transporter (Permease
VagYM4_05250	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
VagYM4_05270	ENOG4105CSR	polyphosphate kinase 2
VagYM4_05280	ENOG4106N3A	copper homeostasis protein cutc
VagYM4_05290	ENOG4105D3R	alkyl hydroperoxide reductase
VagYM4_05300	ENOG4105C5Q	Transcriptional regulator
VagYM4_05310	ENOG4107QP3	malate synthase g
VagYM4_05320	ENOG4108I9X	Isocitrate lyase
VagYM4_05330	ENOG4105W87	Cbs domain
VagYM4_05350	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
VagYM4_05360	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
VagYM4_05370	ENOG4105VIE	preprotein translocase, subunit YajC
VagYM4_05380	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
VagYM4_05390	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
VagYM4_05400	ENOG4105ECY	inositol monophosphatase
VagYM4_05410	ENOG4105CVS	RNA methyltransferase TrmH family, group 1
VagYM4_05420	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
VagYM4_05430	ENOG4105C3J	Cysteine desulfurase
VagYM4_05440	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
VagYM4_05450	ENOG4108Z4V	iron-sulfur cluster assembly
VagYM4_05460	ENOG4108SWN	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA (By similarity)
VagYM4_05470	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
VagYM4_05480	ENOG4108ZIT	Ferredoxin, 2FE-2S
VagYM4_05490	ENOG4105WVQ	Fe-S assembly protein IscX
VagYM4_05500	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
VagYM4_05510	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
VagYM4_05520	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
VagYM4_05540	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
VagYM4_05550	ENOG4105CUT	histidyl-tRNA synthetase
VagYM4_05560	ENOG4105N21	Membrane
VagYM4_05570	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
VagYM4_05580	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
VagYM4_05610	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
VagYM4_05620	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
VagYM4_05630	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
VagYM4_05810	ENOG4107S6Z	Na H antiporter
VagYM4_05830	ENOG4106HK8	GPR1 FUN34 yaaH family protein
VagYM4_05840	ENOG4105BZG	amino acid carrier protein
VagYM4_05850	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
VagYM4_05880	ENOG4108IQK	o-acetylhomoserine
VagYM4_05890	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
VagYM4_05930	ENOG4105DGM	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
VagYM4_05940	ENOG4105ETT	transcriptional Regulator, LysR family
VagYM4_05960	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
VagYM4_05970	ENOG4108Z1B	Cyclase dehydrase
VagYM4_05980	ENOG4105VDB	UPF0125 protein
VagYM4_05990	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
VagYM4_06000	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
VagYM4_06020	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
VagYM4_06030	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
VagYM4_06040	ENOG4105CK2	sodium dicarboxylate symporter
VagYM4_06060	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
VagYM4_06120	ENOG4105CFC	Transporter
VagYM4_06130	ENOG4108Z6B	deaminase
VagYM4_06140	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
VagYM4_06150	ENOG4108ETH	Formylglycinamide ribotide synthetase
VagYM4_06180	ENOG4105X58	receptor
VagYM4_06210	ENOG4105CIN	aminoacyl-histidine dipeptidase
VagYM4_06220	ENOG4105C7N	Xanthine uracil vitamin C permease
VagYM4_06230	ENOG4105DYA	Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity)
VagYM4_06240	ENOG4108DJV	Fermentation respiration switch protein
VagYM4_06250	ENOG4108UVK	Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes. Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32 (By similarity)
VagYM4_06260	ENOG4108UVK	Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes. Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32 (By similarity)
VagYM4_06270	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
VagYM4_06280	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
VagYM4_06290	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
VagYM4_06300	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
VagYM4_06340	ENOG4107YIM	Involved in the transcription termination process (By similarity)
VagYM4_06350	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
VagYM4_06360	ENOG4108ZAI	phosphatidylglycerophosphatase a
VagYM4_06370	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
VagYM4_06380	ENOG4105CTB	Polyprenyl synthetase
VagYM4_06390	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
VagYM4_06400	ENOG4105E14	MotA TolQ exbB proton channel
VagYM4_06410	ENOG4106VK6	Flagellar motor protein
VagYM4_06420	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
VagYM4_06440	ENOG4105ETT	transcriptional Regulator, LysR family
VagYM4_06460	ENOG4105M08	Membrane
VagYM4_06470	ENOG4105EZ6	Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA (By similarity)
VagYM4_06480	ENOG4105CIQ	May have a role in processing of nucleic acids. It is probably not an exonuclease
VagYM4_06490	ENOG4105EWT	decarboxylase family
VagYM4_06520	ENOG4107R1K	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
VagYM4_06530	ENOG4108T6E	Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function (By similarity)
VagYM4_06540	ENOG4105EXF	Zn-ribbon-containing, possibly nucleic-acid-binding protein
VagYM4_06550	ENOG4105D01	(LipO)protein
VagYM4_06560	ENOG4108UMI	ABC transporter, permease
VagYM4_06570	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
VagYM4_06580	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
VagYM4_06590	ENOG4105D4X	repressor
VagYM4_06600	ENOG4105C5Y	PTS System
VagYM4_06610	ENOG4105CG3	alpha amylase, catalytic region
VagYM4_06650	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
VagYM4_06660	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
VagYM4_06670	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
VagYM4_06680	ENOG4108Z43	UPF0250 protein
VagYM4_06690	ENOG4105DZ1	carboxypeptidase
VagYM4_06700	ENOG4105K6T	rare lipoprotein A
VagYM4_06710	ENOG4105CNI	cell division protein FtsW
VagYM4_06720	ENOG4105CJN	penicillin-binding protein
VagYM4_06730	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
VagYM4_06740	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
VagYM4_06750	ENOG4105DJF	DNA polymerase III, delta' subunit
VagYM4_06760	ENOG4108U2H	Rare lipoprotein B
VagYM4_06770	ENOG4105C8T	Leucyl-tRNA synthetase
VagYM4_06780	ENOG4107PAI	alpha helical protein
VagYM4_06790	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
VagYM4_06800	ENOG4108JU5	Magnesium and cobalt efflux protein
VagYM4_06810	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
VagYM4_06820	ENOG4105C9A	Phoh family
VagYM4_06830	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
VagYM4_06840	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
VagYM4_06850	ENOG4105C3G	gtp-binding protein
VagYM4_06860	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
VagYM4_06870	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
VagYM4_06880	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
VagYM4_06890	ENOG4105C1U	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein (By similarity)
VagYM4_06900	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
VagYM4_06910	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
VagYM4_06920	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
VagYM4_06930	ENOG4108YY7	Invasion gene expression up-regulator SirB
VagYM4_06940	ENOG41063JG	Transcriptional regulator
VagYM4_06950	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
VagYM4_06960	ENOG4105CGH	5'-nucleotidase
VagYM4_06970	ENOG4108Z66	YbaK ebsC protein
VagYM4_06980	ENOG4105FE9	pseudouridine synthase
VagYM4_06990	ENOG4108DG9	Smr protein MutS2
VagYM4_07030	ENOG4105E2D	ec 3.2.1.52
VagYM4_07060	ENOG4105C59	p-type ATPase
VagYM4_07070	ENOG41081QG	Porin Gram-negative type
VagYM4_07090	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
VagYM4_07100	ENOG4105UYK	outer membrane protein a
VagYM4_07180	ENOG4107R88	Chemotaxis protein (CheV)
VagYM4_07190	ENOG4105BZU	Histidine kinase
VagYM4_07200	ENOG4105K88	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
VagYM4_07210	ENOG4108ZC9	flagellar basal-body rod protein flgc
VagYM4_07220	ENOG4105W00	Flagellar hook capping protein
VagYM4_07230	ENOG4105BZE	flagellar hook protein, FlgE
VagYM4_07240	ENOG4108KPB	Flagellar basal-body rod protein FlgF
VagYM4_07250	ENOG4105CGA	flagellar basal-body rod protein FlgG
VagYM4_07260	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
VagYM4_07270	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
VagYM4_07280	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
VagYM4_07300	ENOG4105DTJ	flagellar hook-associated protein
VagYM4_07320	ENOG4105I03	Flagellin
VagYM4_07330	ENOG4105I03	Flagellin
VagYM4_07350	ENOG4105C5Y	PTS System
VagYM4_07360	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
VagYM4_07380	ENOG4105KZ7	phosphocarrier protein hpr
VagYM4_07390	ENOG4105C6T	cysteine synthase
VagYM4_07400	ENOG4105EXN	Sulfate transport protein CysZ
VagYM4_07410	ENOG4107NPY	receptor for the septal ring structure, may anchor it to the inner-membrane (By similarity)
VagYM4_07420	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
VagYM4_07470	ENOG4107QX8	SPFH domain, Band 7 family protein
VagYM4_07480	ENOG4107QR8	Thioredoxin
VagYM4_07490	ENOG4105E1F	short-chain dehydrogenase reductase
VagYM4_07500	ENOG4105ECP	epimerase
VagYM4_07560	ENOG4108RE9	Phosphodiesterase
VagYM4_07600	ENOG4108DQ1	activator toxR
VagYM4_07610	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
VagYM4_07620	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
VagYM4_07630	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
VagYM4_07650	ENOG4105DUX	Transporter
VagYM4_07660	ENOG4105MDZ	Transcriptional activator rfaH
VagYM4_07670	ENOG4105CAQ	asparagine synthetase
VagYM4_07680	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
VagYM4_07690	ENOG4105E2R	ROK family
VagYM4_07700	ENOG4105CE4	GlcNAc 6-P deacetylase
VagYM4_07710	ENOG4105CI1	PTS System
VagYM4_07720	ENOG4105CX6	glutaminyL-tRNA synthetase
VagYM4_07730	ENOG41090R7	Ferric uptake
VagYM4_07750	ENOG4105MHQ	Low-potential electron donor to a number of redox enzymes (By similarity)
VagYM4_07770	ENOG4105EV9	Alpha Beta Hydrolase
VagYM4_07780	ENOG4107CDU	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated (By similarity)
VagYM4_07790	ENOG4107QIX	Phosphoglucomutase (EC 5.4.2.2
VagYM4_07810	ENOG4107QNR	UPF0135 protein
VagYM4_07820	ENOG4105BZN	citrate synthase
VagYM4_07830	ENOG4108UTY	succinate dehydrogenase, cytochrome b556 subunit
VagYM4_07840	ENOG4105N1I	succinate dehydrogenase, hydrophobic membrane anchor protein
VagYM4_07850	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
VagYM4_07860	ENOG4105E33	succinate dehydrogenase
VagYM4_07870	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
VagYM4_07880	ENOG4105C7S	Dehydrogenase
VagYM4_07890	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
VagYM4_07900	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
VagYM4_07910	ENOG4105FAV	ABC, transporter
VagYM4_07920	ENOG4105FDK	ABC transporter
VagYM4_07930	ENOG4105NXV	High-affinity zinc uptake system protein
VagYM4_07940	ENOG4107S4Z	Activates expression of the rhaBAD and rhaT operons (By similarity)
VagYM4_07950	ENOG4105XFK	Ferrous iron transport protein A
VagYM4_07960	ENOG4105CE1	Ferrous iron transport protein b
VagYM4_07990	ENOG4105C75	arginyL-tRNA synthetase
VagYM4_08000	ENOG4106ZCM	YecM protein
VagYM4_08020	ENOG4105NDH	peptidase s1 and s6 chymotrypsin hap
VagYM4_08030	ENOG4105CIY	formyltetrahydrofolate deformylase
VagYM4_08040	ENOG4105DVT	helicase
VagYM4_08050	ENOG41072GX	Peptidase M22 Glycoprotease
VagYM4_08070	ENOG4105R8X	Outer membrane lipoprotein Slp
VagYM4_08080	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
VagYM4_08090	ENOG4105CEY	Amp-dependent synthetase and ligase
VagYM4_08100	ENOG4105ZIE	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity)
VagYM4_08110	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
VagYM4_08120	ENOG4107QMS	site-determining protein
VagYM4_08130	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
VagYM4_08140	ENOG4105VNG	YcgL domain-containing protein
VagYM4_08150	ENOG4105CVE	Lytic murein transglycosylase
VagYM4_08170	ENOG4105D9N	nucleoside
VagYM4_08180	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
VagYM4_08190	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
VagYM4_08210	ENOG4105C2D	reductase
VagYM4_08230	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
VagYM4_08280	ENOG4105C84	Histidine ammonia-lyase
VagYM4_08290	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
VagYM4_08300	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
VagYM4_08340	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
VagYM4_08420	ENOG4105C1J	atp-dependent rna helicase
VagYM4_08430	ENOG4107ZYR	domain protein
VagYM4_08470	ENOG4105CNG	UPF0061 protein
VagYM4_08480	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
VagYM4_08490	ENOG410835K	Tripartite ATP-Independent Periplasmic transporter DctQ
VagYM4_08500	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
VagYM4_08510	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
VagYM4_08520	ENOG4105CQZ	Histidine kinase
VagYM4_08530	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
VagYM4_08540	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
VagYM4_08550	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
VagYM4_08560	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
VagYM4_08570	ENOG4105K70	DNA-binding protein
VagYM4_08580	ENOG4105EIN	peptidylprolyl cis-trans isomerase
VagYM4_08590	ENOG41083P1	competence protein ComEA helix-hairpin-helix repeat protein
VagYM4_08620	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
VagYM4_08630	ENOG4105DK2	UPF0207 protein
VagYM4_08640	ENOG4105CHM	Aminotransferase
VagYM4_08650	ENOG4105E4F	Isochorismate synthase
VagYM4_08660	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
VagYM4_08670	ENOG4107J5P	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity)
VagYM4_08680	ENOG4108IPT	Naphthoate synthase
VagYM4_08700	ENOG4105CEY	Amp-dependent synthetase and ligase
VagYM4_08720	ENOG4105HMI	Membrane
VagYM4_08730	ENOG4108J8Q	Catalyzes the facilitated diffusion of 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) into the cell (By similarity)
VagYM4_08760	ENOG4105EP1	Efflux transporter rnd family, mfp subunit
VagYM4_08770	ENOG4105BZS	acriflavin resistance protein
VagYM4_08810	ENOG4105C6T	cysteine synthase
VagYM4_08820	ENOG4108XM1	transcriptional regulator AsnC family
VagYM4_08840	ENOG4105C29	acyl-CoA thioesterase
VagYM4_08850	ENOG4108MNP	Glycoprotein polysaccharide metabolism
VagYM4_08920	ENOG4105ETT	transcriptional Regulator, LysR family
VagYM4_08990	ENOG4107RSM	transcriptional regulator
VagYM4_09000	ENOG4105IGJ	Zn-dependent Hydrolase of the beta-lactamase fold protein
VagYM4_09010	ENOG4105E7U	AraC family transcriptional regulator
VagYM4_09030	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
VagYM4_09050	ENOG4107SXA	Phosphorylase
VagYM4_09070	ENOG4108NVR	Methyl-accepting chemotaxis
VagYM4_09080	ENOG4105K59	histidine triad (HIT) protein
VagYM4_09130	ENOG4105D0Y	UPF0227 protein
VagYM4_09140	ENOG4105CEP	NADH dehydrogenase
VagYM4_09170	ENOG4108JA2	transcriptioN-repair coupling factor
VagYM4_09190	ENOG4105D60	lipoprotein releasing system transmembrane protein
VagYM4_09200	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
VagYM4_09210	ENOG4105D60	lipoprotein releasing system transmembrane protein
VagYM4_09230	ENOG4108EQH	DNA internalization-related competence protein ComEC Rec2
VagYM4_09240	ENOG4105BZ1	(ABC) transporter
VagYM4_09250	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
VagYM4_09260	ENOG4105W49	UPF0434 protein
VagYM4_09270	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
VagYM4_09280	ENOG4105ED1	spovr family
VagYM4_09290	ENOG4106AKX	UPF0229 protein
VagYM4_09300	ENOG4105CYN	Serine protein kinase
VagYM4_09310	ENOG4105XWI	UPF0304 protein
VagYM4_09330	ENOG4105F1A	Pyruvate formate-lyase
VagYM4_09350	ENOG4105C6N	Formate acetyltransferase
VagYM4_09380	ENOG4108JEH	abc transporter atp-binding protein
VagYM4_09390	ENOG4105E89	ABC transporter
VagYM4_09400	ENOG4105DSP	amino acid AbC transporter
VagYM4_09430	ENOG4105CGK	Exodeoxyribonuclease III
VagYM4_09440	ENOG4106428	Protein of unknown function (DUF2496)
VagYM4_09450	ENOG4108URS	primosomal replication protein n''
VagYM4_09460	ENOG4105EJ9	Membrane
VagYM4_09470	ENOG4105DVT	helicase
VagYM4_09480	ENOG4105SDR	Outer membrane protein OmpT
VagYM4_09500	ENOG4108R99	pseudouridine synthase
VagYM4_09520	ENOG4105VEQ	Cold shock protein
VagYM4_09530	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
VagYM4_09540	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
VagYM4_09550	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
VagYM4_09560	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
VagYM4_09570	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
VagYM4_09590	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
VagYM4_09600	ENOG4105RKX	Protein of unknown function (DUF2498)
VagYM4_09610	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
VagYM4_09620	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
VagYM4_09630	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
VagYM4_09670	ENOG4105HP8	regulator of competence-specific genes
VagYM4_09680	ENOG4105ETE	Transcriptional regulator (LacI family
VagYM4_09690	ENOG4109039	Involved in the biogenesis of TorA. Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor (By similarity)
VagYM4_09700	ENOG4106WF9	DNA-binding transcriptional regulator TorR
VagYM4_09710	ENOG4107S90	membrAne
VagYM4_09720	ENOG4106371	Methyltransferase
VagYM4_09730	ENOG4105GHU	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity (By similarity)
VagYM4_09740	ENOG4105DAH	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF (By similarity)
VagYM4_09750	ENOG4105DUC	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division (By similarity)
VagYM4_09790	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
VagYM4_09800	ENOG4105PFA	Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity)
VagYM4_09810	ENOG4105DA6	Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity)
VagYM4_09820	ENOG41081XQ	Conserved Protein
VagYM4_09830	ENOG4105C9M	aspartyl-trna synthetase
VagYM4_09840	ENOG4105CDY	transcriptional regulatory protein
VagYM4_09850	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
VagYM4_09860	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
VagYM4_09870	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
VagYM4_09880	ENOG4105C4M	(Ubiquinol oxidase) subunit I
VagYM4_09890	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
VagYM4_09920	ENOG4107YD3	Thioesterase
VagYM4_09930	ENOG4105E02	MotA TolQ exbB proton channel
VagYM4_09940	ENOG4105M8F	Biopolymer transport protein exbD tolR
VagYM4_09960	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
VagYM4_09970	ENOG4105KCK	Peptidoglycan-associated lipoprotein
VagYM4_09980	ENOG4105UFD	tol-pal system protein YbgF
VagYM4_09990	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
VagYM4_10010	ENOG4105Z6B	inner membrane protein yjfl
VagYM4_10030	ENOG4106032	Glutathionylspermidine synthase
VagYM4_10050	ENOG4105BZU	Histidine kinase
VagYM4_10060	ENOG4108RNS	Exports L-alanine (By similarity)
VagYM4_10070	ENOG4105C8Q	Methyl-accepting chemotaxis
VagYM4_10080	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
VagYM4_10090	ENOG4105BZS	acriflavin resistance protein
VagYM4_10160	ENOG4105C8Q	Methyl-accepting chemotaxis
VagYM4_10170	ENOG4105FR9	TRNA-(Ms 2 io 6 A)-hydroxylase
VagYM4_10190	ENOG4107R11	Transcriptional regulator
VagYM4_10210	ENOG4105DCF	alanine dehydrogenase
VagYM4_10220	ENOG4105EW9	transcriptional regulator AsnC family
VagYM4_10230	ENOG4105CNU	cell division protein FtsK
VagYM4_10240	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
VagYM4_10250	ENOG4105D1H	recombination factor protein RarA
VagYM4_10260	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
VagYM4_10300	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
VagYM4_10310	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
VagYM4_10320	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
VagYM4_10330	ENOG4105EWW	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
VagYM4_10350	ENOG4105D0M	Protease HtpX homolog
VagYM4_10380	ENOG4107FW0	short-chain dehydrogenase reductase
VagYM4_10410	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
VagYM4_10430	ENOG4105RHG	
VagYM4_10450	ENOG4107QTF	adenylosuccinate lyase
VagYM4_10460	ENOG41075W9	High frequency lysogenization protein HflD homolog
VagYM4_10470	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
VagYM4_10490	ENOG4107RE1	Inosine-guanosine kinase
VagYM4_10500	ENOG4108YX2	DNA-binding protein
VagYM4_10510	ENOG4107S6Z	Na H antiporter
VagYM4_10520	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
VagYM4_10530	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
VagYM4_10540	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
VagYM4_10550	ENOG4105CIH	Imidazole acetol-phosphate transaminase
VagYM4_10560	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
VagYM4_10590	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
VagYM4_10630	ENOG4105J12	Multidrug resistance protein mdtN
VagYM4_10640	ENOG4105JQN	Transcriptional regulator
VagYM4_10680	ENOG41062D9	Histidine kinase
VagYM4_10690	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
VagYM4_10700	ENOG4105C8Q	Methyl-accepting chemotaxis
VagYM4_10730	ENOG4105CCT	upf0313 protein
VagYM4_10770	ENOG4105DZ2	Transcriptional regulator
VagYM4_10780	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
VagYM4_10800	ENOG4105K9H	YciI-like protein
VagYM4_10810	ENOG4105NAU	thioesterase Superfamily protein
VagYM4_10820	ENOG4107835	probably involved in intracellular septation (By similarity)
VagYM4_10840	ENOG4105BZU	Histidine kinase
VagYM4_10860	ENOG4105CK2	sodium dicarboxylate symporter
VagYM4_10870	ENOG4105CEY	Amp-dependent synthetase and ligase
VagYM4_10880	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
VagYM4_10890	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
VagYM4_10900	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
VagYM4_10910	ENOG4105DK0	Indole-3-glycerol phosphate synthase
VagYM4_10920	ENOG4108I0Q	anthranilate phosphoribosyltransferase
VagYM4_10930	ENOG4105DDQ	anthranilate synthase
VagYM4_10940	ENOG4105CRQ	synthase (Component I)
VagYM4_10960	ENOG4105DB7	PHP domain protein
VagYM4_10970	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
VagYM4_11000	ENOG4105FE9	pseudouridine synthase
VagYM4_11010	ENOG4108W5H	UPF0263 protein
VagYM4_11040	ENOG4105CQ2	DNA polymerase
VagYM4_11050	ENOG4105WH1	Two component transcriptional regulator luxr family
VagYM4_11060	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
VagYM4_11100	ENOG4105D3D	Catalyzes the decarboxylation of carboxynorspermidine and carboxyspermidine (By similarity)
VagYM4_11150	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
VagYM4_11160	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
VagYM4_11170	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
VagYM4_11190	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
VagYM4_11220	ENOG4105EAU	Plays a role in nitrite reduction (By similarity)
VagYM4_11240	ENOG4105D3S	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
VagYM4_11250	ENOG4105DVI	reductase, NrfD
VagYM4_11260	ENOG4105DA4	cytochrome c-type biogenesis protein
VagYM4_11270	ENOG4107QX9	Thiol disulfide interChange protein
VagYM4_11280	ENOG4108DMF	Cytochrome C biogenesis protein
VagYM4_11300	ENOG4107T1C	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity)
VagYM4_11350	ENOG4105DIT	ErfK YbiS YcfS YnhG family protein
VagYM4_11360	ENOG4105EAQ	(twin-arginine translocation) pathway signal
VagYM4_11370	ENOG4105C5X	domain protein
VagYM4_11400	ENOG4105CH5	extracellular solute-binding protein, family 7
VagYM4_11420	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
VagYM4_11460	ENOG4105C94	Transporter
VagYM4_11470	ENOG4105C8Q	Methyl-accepting chemotaxis
VagYM4_11510	ENOG4105CGF	Aromatic amino acid aminotransferase
VagYM4_11540	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
VagYM4_11560	ENOG4105C5S	asparaginyl-tRNA synthetase
VagYM4_11570	ENOG4105C8Q	Methyl-accepting chemotaxis
VagYM4_11590	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
VagYM4_11610	ENOG4105BZU	Histidine kinase
VagYM4_11620	ENOG4105EJQ	L-serine dehydratase
VagYM4_11630	ENOG4105C44	Serine transporter
VagYM4_11640	ENOG4105P8F	nudix hydrolase
VagYM4_11670	ENOG4105CRQ	synthase (Component I)
VagYM4_11700	ENOG4105CM6	amino acid regulated cytosolic protein
VagYM4_11710	ENOG4106K28	UPF0283 membrane protein
VagYM4_11730	ENOG4105D9U	N-acetyltransferase
VagYM4_12180	ENOG4105CFU	surface antigen
VagYM4_12190	ENOG4107RZC	phospholipase d
VagYM4_12200	ENOG4105EBR	Carboxylesterase
VagYM4_12250	ENOG4105Y49	secretion protein, HlyD family
VagYM4_12270	ENOG4105D0C	transport protein
VagYM4_12280	ENOG4105CEB	Aspartate aminotransferase
VagYM4_12320	ENOG4105DUM	transcriptional regulator, lysR family
VagYM4_12380	ENOG41088T4	Helicase IV
VagYM4_12410	ENOG4108QDQ	Ubiquinol-cytochrome C chaperone 
VagYM4_12480	ENOG4105W2W	Cytotoxic translational repressor of toxin-antitoxin stability system
VagYM4_12490	ENOG4105W08	virulence gene repressor rsal
VagYM4_12560	ENOG4105Y49	secretion protein, HlyD family
VagYM4_12590	ENOG4107V40	secretion protein, HlyD family
VagYM4_12620	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
VagYM4_12630	ENOG4106YYS	transcriptional regulatory protein
VagYM4_12640	ENOG4105E0K	tonB-dependent siderophore receptor
VagYM4_12650	ENOG4108XW0	May be a transcriptional activator of genes involved in the multiple antibiotic resistance (Mar) phenotype. It can also activate genes such as sodA, zwf and micF
VagYM4_12660	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
VagYM4_12670	ENOG4108Q79	6-phosphogluconolactonase (EC 3.1.1.31)
VagYM4_12680	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
VagYM4_12710	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
VagYM4_12720	ENOG4105C26	Dehydrogenase
VagYM4_12760	ENOG4108KB1	transcriptional regulator, arac family
VagYM4_12820	ENOG41066XE	Type III export protein
VagYM4_12960	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
VagYM4_13000	ENOG41062JF	Transcriptional regulator
VagYM4_13220	ENOG4105H1G	trap transporter solute receptor taxi family
VagYM4_13230	ENOG4105EJ9	Membrane
VagYM4_13300	ENOG4105CR4	methylisocitrate lyase
VagYM4_13310	ENOG4105BZN	citrate synthase
VagYM4_13320	ENOG4108I0Z	Aconitate hydratase
VagYM4_13330	ENOG4105C7F	AcnD-accessory protein PrpF
VagYM4_13340	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
VagYM4_13360	ENOG4105NDH	peptidase s1 and s6 chymotrypsin hap
VagYM4_13380	ENOG410667J	hydrolase
VagYM4_13390	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
VagYM4_13400	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
VagYM4_13410	ENOG4105BZU	Histidine kinase
VagYM4_13430	ENOG4105CDV	Ompa motb domain protein
VagYM4_13460	ENOG4105CDV	Ompa motb domain protein
VagYM4_13490	ENOG4105DR4	Methyltransferase
VagYM4_13500	ENOG4105C8Q	Methyl-accepting chemotaxis
VagYM4_13510	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
VagYM4_13520	ENOG4108Z0T	Part of a sulfur-relay system (By similarity)
VagYM4_13540	ENOG4108MN8	Membrane
VagYM4_13550	ENOG4105CDA	abc transporter atp-binding protein
VagYM4_13560	ENOG4105DRP	amino acid AbC transporter
VagYM4_13570	ENOG4105EZ7	amino acid ABC transporter
VagYM4_13580	ENOG4107QXX	ABC transporter
VagYM4_13600	ENOG4108VPT	UPF0234 protein
VagYM4_13610	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
VagYM4_13650	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
VagYM4_13660	ENOG4105DY2	Paraquat-inducible protein b
VagYM4_13670	ENOG4105H2K	paraquat-inducible protein a
VagYM4_13680	ENOG4105BZ1	(ABC) transporter
VagYM4_13690	ENOG4108ZGC	gaf domain protein
VagYM4_13700	ENOG41073DY	may be a structural element that influences the osmotic activation of ProP at a post-translational level (By similarity)
VagYM4_13710	ENOG4105CN1	protease
VagYM4_13730	ENOG4105CD8	aminopeptidase N
VagYM4_13750	ENOG4105C7I	Dehydrogenase
VagYM4_13760	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
VagYM4_13770	ENOG4108T7E	Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ (By similarity)
VagYM4_13780	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
VagYM4_13800	ENOG4105C5H	ABC transporter
VagYM4_13830	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
VagYM4_13840	ENOG4105DAN	ATP-dependent protease
VagYM4_13850	ENOG4108R9Q	Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle. Prevents early segregation of duplicated Ter macrodomains during cell division. Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain (By similarity)
VagYM4_13910	ENOG4105VZ1	Replication Protein
VagYM4_14120	ENOG4105BZU	Histidine kinase
VagYM4_14150	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
VagYM4_14180	ENOG4105D6P	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex (By similarity)
VagYM4_14200	ENOG4105C59	p-type ATPase
VagYM4_14230	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
VagYM4_14240	ENOG4105Q9Y	Universal stress protein
VagYM4_14250	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
VagYM4_14290	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
VagYM4_14310	ENOG4105D38	putrescine abc transporter
VagYM4_14320	ENOG4108HM4	ABC transporter
VagYM4_14330	ENOG4107RUE	extracellular solute-binding protein family 1
VagYM4_14340	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
VagYM4_14410	ENOG4105QAX	Iron-sulfur
VagYM4_14420	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
VagYM4_14440	ENOG4109039	Involved in the biogenesis of TorA. Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor (By similarity)
VagYM4_14480	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
VagYM4_14500	ENOG4105C5H	ABC transporter
VagYM4_14510	ENOG4105BZU	Histidine kinase
VagYM4_14520	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
VagYM4_14550	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
VagYM4_14560	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
VagYM4_14570	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
VagYM4_14590	ENOG4105EZX	Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P (By similarity)
VagYM4_14600	ENOG4106IUH	DTW domain containing protein
VagYM4_14660	ENOG4107TT5	NLP P60 protein
VagYM4_14680	ENOG4105BZU	Histidine kinase
VagYM4_14720	ENOG4108R6K	riboflavin synthase, subunit alpha
VagYM4_14730	ENOG4107QI1	Mate efflux family protein
VagYM4_14760	ENOG41082AN	stage II sporulation protein
VagYM4_14780	ENOG4107V1M	polysaccharide export protein
VagYM4_14810	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
VagYM4_14830	ENOG4107TYR	Glycosyl Transferase
VagYM4_14890	ENOG4105CPK	Glycosyl transferase (Group 1
VagYM4_14900	ENOG4107R8N	Glycosyl transferase, family 2
VagYM4_14930	ENOG4105C94	Transporter
VagYM4_14960	ENOG4105CQ7	ATP-dependent helicase
VagYM4_14970	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
VagYM4_15060	ENOG4105CFG	Acts as a chaperone (By similarity)
VagYM4_15070	ENOG4105CFG	Acts as a chaperone (By similarity)
VagYM4_15110	ENOG4106855	Competence protein
VagYM4_15120	ENOG4105BZ1	(ABC) transporter
VagYM4_15130	ENOG4105BZ1	(ABC) transporter
VagYM4_15150	ENOG4105E0K	tonB-dependent siderophore receptor
VagYM4_15160	ENOG4105E0K	tonB-dependent siderophore receptor
VagYM4_15170	ENOG4105S6R	Iron-hydroxamate transporter permease subunit
VagYM4_15180	ENOG4105J76	Periplasmic binding protein
VagYM4_15190	ENOG4105E0A	ABC, transporter
VagYM4_15210	ENOG4105CPI	Metal Dependent Phosphohydrolase
VagYM4_15220	ENOG4105E0U	tyrosine-specific transport protein
VagYM4_15240	ENOG4105DHT	Metal Dependent Phosphohydrolase
VagYM4_15260	ENOG4105EE5	Membrane protein terC
VagYM4_15280	ENOG41076CZ	activating enzyme
VagYM4_15290	ENOG4105G0K	glycine radical enzyme YjjI family
VagYM4_15300	ENOG410829K	Lysine exporter protein (Lyse ygga)
VagYM4_15310	ENOG4105CPI	Metal Dependent Phosphohydrolase
VagYM4_15320	ENOG4105BZU	Histidine kinase
VagYM4_15330	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
VagYM4_15350	ENOG4105C8P	)-transporter
VagYM4_15400	ENOG41090KN	UPF0303 protein
VagYM4_15410	ENOG4105D9R	oxidoreductase
VagYM4_15450	ENOG4105C4X	radical SAM domain protein
VagYM4_15490	ENOG4105ENH	Sulfatase
VagYM4_15500	ENOG4105CZK	Aspartate kinase
VagYM4_15510	ENOG4108Z6K	Catalyzes the circularization of gamma-N-acetyl- alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6- tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant (By similarity)
VagYM4_15520	ENOG4108JPW	Aminotransferase
VagYM4_15530	ENOG4108Z24	l-2,4-diaminobutyric acid acetyltransferase
VagYM4_15540	ENOG4105C94	Transporter
VagYM4_15570	ENOG4108IJ7	Glycine betaine
VagYM4_15580	ENOG4108HQS	Glycine betaine
VagYM4_15590	ENOG4105GIJ	Glycine betaine
VagYM4_15660	ENOG4105DHQ	Histidine kinase
VagYM4_15670	ENOG4105E0M	Sulfatase
VagYM4_15750	ENOG4105BZG	amino acid carrier protein
VagYM4_15770	ENOG410829K	Lysine exporter protein (Lyse ygga)
VagYM4_15780	ENOG4105CTD	carboxy-peptidase
VagYM4_15850	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
VagYM4_15880	ENOG4105KT5	UmuD protein
VagYM4_15890	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
VagYM4_15900	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
VagYM4_15910	ENOG4108MZY	
VagYM4_15930	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
VagYM4_16000	ENOG4107SVC	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
VagYM4_16050	ENOG4105FDK	ABC transporter
VagYM4_16100	ENOG4105C0D	helicase
VagYM4_16120	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
VagYM4_16190	ENOG4107TII	Recombinase
VagYM4_16200	ENOG4105CTD	carboxy-peptidase
VagYM4_16210	ENOG4105D1S	lipid A biosynthesis
VagYM4_16230	ENOG4105E5D	amino acid
VagYM4_16260	ENOG4105CVG	Homoserine O-transsuccinylase
VagYM4_16270	ENOG41090FY	type IV pilus biogenesis stability protein PilW
VagYM4_16290	ENOG4105BZU	Histidine kinase
VagYM4_16300	ENOG4105BZU	Histidine kinase
VagYM4_16330	ENOG4108UW5	maltose o-acetyltransferase
VagYM4_16360	ENOG4105MSB	protein, conserved in bacteria
VagYM4_16370	ENOG4108ZT1	Transcriptional regulator
VagYM4_16390	ENOG4105CXC	rtn protein
VagYM4_16440	ENOG4108RXX	maleylacetoacetate isomerase
VagYM4_16460	ENOG4105F1J	Homogentisate 1,2-dioxygenase
VagYM4_16470	ENOG4105E6K	4-Hydroxyphenylpyruvate dioxygenase
VagYM4_16480	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
VagYM4_16490	ENOG4107QSI	ABC, transporter
VagYM4_16500	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
VagYM4_16510	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
VagYM4_16520	ENOG4105C3U	ABC transporter
VagYM4_16530	ENOG4108JQ7	(ABC) transporter
VagYM4_16550	ENOG4107MM9	BNR Asp-box repeat-containing protein
VagYM4_16580	ENOG4105D38	putrescine abc transporter
VagYM4_16590	ENOG4105F38	ABC transporter, permease
VagYM4_16600	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
VagYM4_16610	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
VagYM4_16620	ENOG4105CIF	Ornithine Cyclodeaminase
VagYM4_16650	ENOG4105CTU	Proline racemase
VagYM4_16710	ENOG4105EBA	Specifically methylates the adenine in position 1618 of 23S rRNA (By similarity)
VagYM4_16720	ENOG4108VKG	metal-dependent hydrolase
VagYM4_16740	ENOG4105F04	LysR family Transcriptional regulator
VagYM4_16780	ENOG41080WI	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system (By similarity)
VagYM4_16790	ENOG4108IU2	vtamin B12-transporter permease
VagYM4_16800	ENOG4107UI5	Transforms N(2)-succinylglutamate into succinate and glutamate (By similarity)
VagYM4_16840	ENOG4108UHF	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
VagYM4_16850	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
VagYM4_16860	ENOG4105K4T	epimerase
VagYM4_16870	ENOG4108ETY	sodium dicarboxylate symporter
VagYM4_16880	ENOG4105CJB	Exodeoxyribonuclease I
VagYM4_16890	ENOG4105VAW	lrga family
VagYM4_16900	ENOG41067MG	lrgb family
VagYM4_16910	ENOG4107T42	This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis (By similarity)
VagYM4_16920	ENOG4108HH9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
VagYM4_16930	ENOG4105FQ6	thiopurine methyltransferase
VagYM4_16950	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
VagYM4_16970	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
VagYM4_16980	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
VagYM4_17040	ENOG4105K8R	UPF0145 protein
VagYM4_17050	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
VagYM4_17060	ENOG41082NX	50s ribosomal protein l35
VagYM4_17070	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
VagYM4_17080	ENOG4105C22	threonyL-tRNA synthetase
VagYM4_17110	ENOG4105CZE	histidine utilization repressor
VagYM4_17120	ENOG4105CI2	imidazolone-5-propionate hydrolase
VagYM4_17130	ENOG41088SP	formiminoglutamate hydrolase
VagYM4_17150	ENOG4105C84	Histidine ammonia-lyase
VagYM4_17180	ENOG4105CQB	FAD linked oxidase domain protein
VagYM4_17210	ENOG4105CDV	Ompa motb domain protein
VagYM4_17250	ENOG4105C8V	SAICAR synthetase
VagYM4_17280	ENOG4105CQ7	ATP-dependent helicase
VagYM4_17290	ENOG4107R1I	NAD-dependent malic enzyme
VagYM4_17300	ENOG4107GZ4	SanA protein
VagYM4_17310	ENOG4105C8P	)-transporter
VagYM4_17320	ENOG4105C8P	)-transporter
VagYM4_17380	ENOG4105C3M	thioredoxin reductase
VagYM4_17390	ENOG4108JJ9	ABC, transporter
VagYM4_17400	ENOG4108JJ8	(ABC) transporter
VagYM4_17420	ENOG4105KCK	Peptidoglycan-associated lipoprotein
VagYM4_17450	ENOG4105CW0	outer membrane usher protein
VagYM4_17460	ENOG4108NAE	Fimbrial chaperone protein
VagYM4_17480	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
VagYM4_17500	ENOG4105BZU	Histidine kinase
VagYM4_17560	ENOG4105DWU	Membrane
VagYM4_17580	ENOG4105DY8	decarboxylase
VagYM4_17590	ENOG4106KNT	transcriptional regulator
VagYM4_17610	ENOG41090BQ	Glutaredoxin
VagYM4_17620	ENOG4105D0C	transport protein
VagYM4_17630	ENOG4105RKW	reductase (By
VagYM4_17640	ENOG4107QPN	acyl-Coa dehydrogenase
VagYM4_17650	ENOG41067SE	Tetr family transcriptional regulator
VagYM4_17660	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
VagYM4_17700	ENOG4107QI1	Mate efflux family protein
VagYM4_17710	ENOG4105CGD	Nad-dependent epimerase dehydratase
VagYM4_17720	ENOG4105CUW	cytochrome C-TYPE protein
VagYM4_17780	ENOG4105C2C	drug resistance transporter, Bcr CflA
VagYM4_17790	ENOG4105I08	Pseudouridine synthase
VagYM4_17800	ENOG4105CFI	type iii restriction protein res subunit
VagYM4_17820	ENOG4105ETX	regulatoR
VagYM4_17830	ENOG4105EB3	Histidine kinase
VagYM4_17840	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
VagYM4_17860	ENOG4105CGH	5'-nucleotidase
VagYM4_17890	ENOG4105VNH	ABC transporter solute-binding protein
VagYM4_17900	ENOG4105CXZ	ABC transporter, permease
VagYM4_17910	ENOG4108VGW	abc transporter atp-binding protein
VagYM4_17920	ENOG4108T9J	Cdp-alcohol phosphatidyltransferase
VagYM4_17940	ENOG4108JUA	Transcriptional regulator
VagYM4_17950	ENOG4105EJ7	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity)
VagYM4_17960	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
VagYM4_17980	ENOG4108W1A	pseudouridine synthase
VagYM4_17990	ENOG4105C8J	)-transporter
VagYM4_18000	ENOG4105C8J	)-transporter
VagYM4_18010	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
VagYM4_18020	ENOG4105C28	cystathionine
VagYM4_18030	ENOG4107IFA	Lipase (EC 3.1.1.3)
VagYM4_18050	ENOG4108R3E	Dna-3-methyladenine glycosylase i
VagYM4_18090	ENOG4105FM1	phage shock protein C
VagYM4_18100	ENOG4105YYT	phage shock protein B
VagYM4_18110	ENOG41087YS	Phage shock protein A
VagYM4_18120	ENOG4105E51	psp operon transcriptional activator
VagYM4_18130	ENOG4108J59	Extracellular solute-binding protein, family 5
VagYM4_18140	ENOG4108EKA	peptide transport system, permease
VagYM4_18150	ENOG4108EU3	peptide transport system, permease
VagYM4_18160	ENOG4108JQ3	Peptide ABC transporter ATP-binding protein
VagYM4_18170	ENOG4108JQ2	peptide transport system atp-binding protein
VagYM4_18190	ENOG4105E2M	Manganese-dependent inorganic pyrophosphatase
VagYM4_18220	ENOG4108J2R	molybdopterin oxidoreductase
VagYM4_18270	ENOG4105TMB	Formate nitrite transporter
VagYM4_18320	ENOG4107DB1	DUF218 domain
VagYM4_18330	ENOG4107104	thymidine kinase
VagYM4_18340	ENOG4105C8N	cysteinyl-tRNA synthetase
VagYM4_18350	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
VagYM4_18360	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
VagYM4_18370	ENOG4105D58	Diguanylate phosphodiesterase
VagYM4_18380	ENOG4105K5B	UPF0225 protein
VagYM4_18440	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
VagYM4_18460	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
VagYM4_18480	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
VagYM4_18510	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
VagYM4_18530	ENOG4105N6Y	Thioredoxin
VagYM4_18540	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
VagYM4_18560	ENOG4108ZXC	Two component transcriptional regulator, luxr family
VagYM4_18570	ENOG4106AFQ	Histidine kinase
VagYM4_18580	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
VagYM4_18590	ENOG4106WHD	Tetrathionate reductase
VagYM4_18600	ENOG4105DB1	molybdopterin oxidoreductase
VagYM4_18620	ENOG4105NQN	cytochrome C
VagYM4_18630	ENOG4105F1S	paraquat-inducible protein a
VagYM4_18640	ENOG4105DY2	Paraquat-inducible protein b
VagYM4_18670	ENOG4108J59	Extracellular solute-binding protein, family 5
VagYM4_18680	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
VagYM4_18690	ENOG4105CFV	Tetratricopeptide repeat protein
VagYM4_18700	ENOG4105Q4A	inner membrane protein yciS
VagYM4_18710	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
VagYM4_18720	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
VagYM4_18730	ENOG4105CAT	Cytidine monophosphate kinase
VagYM4_18740	ENOG4105ERU	peptidase
VagYM4_18750	ENOG4105UBK	short-chain dehydrogenase reductase
VagYM4_18780	ENOG4105C0B	DNA polymerase III (alpha subunit)
VagYM4_18800	ENOG4105DAG	ROK family
VagYM4_18810	ENOG4105CA9	Pyruvate kinase
VagYM4_18820	ENOG4108NRW	Phospholipase, patatin family
VagYM4_18850	ENOG4105C8J	)-transporter
VagYM4_18880	ENOG4105CI1	PTS System
VagYM4_18890	ENOG4105F8V	Hydrolase, tatD family
VagYM4_18900	ENOG4107QRG	dna polymerase iii
VagYM4_18910	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
VagYM4_18920	ENOG4105HHA	aminodeoxychorismate lyase
VagYM4_18940	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
VagYM4_18950	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
VagYM4_18960	ENOG4105CHR	reductase
VagYM4_18970	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
VagYM4_18980	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
VagYM4_18990	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
VagYM4_19000	ENOG4105VGS	50s ribosomal protein l32
VagYM4_19010	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
VagYM4_19020	ENOG4108UHJ	MAF-like protein
VagYM4_19030	ENOG4105EI2	Pseudouridine synthase
VagYM4_19040	ENOG4105C03	ribonuclease
VagYM4_19050	ENOG4105CHH	sulfate transporter
VagYM4_19060	ENOG4105KJF	protein tyrosine phosphatase
VagYM4_19070	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
VagYM4_19090	ENOG4105DBI	uridine monophosphokinase
VagYM4_19100	ENOG4105D1F	ATP-binding protein
VagYM4_19110	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
VagYM4_19140	ENOG4105C05	Multifunctional regulator of fatty acid metabolism (By similarity)
VagYM4_19160	ENOG410635M	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
VagYM4_19170	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
VagYM4_19180	ENOG4105FBT	Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity)
VagYM4_19190	ENOG4105BZU	Histidine kinase
VagYM4_19200	ENOG4107R28	alpha amylase, catalytic region
VagYM4_19210	ENOG4108JJB	ABC transporter
VagYM4_19220	ENOG4105C7J	ABC transporter, permease
VagYM4_19240	ENOG4105PQ6	UPF0208 membrane protein
VagYM4_19250	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
VagYM4_19260	ENOG4108DNC	Involved in acetate metabolism (By similarity)
VagYM4_19270	ENOG4107PU6	Membrane
VagYM4_19290	ENOG4105CHF	Glutathione S-transferase
VagYM4_19300	ENOG4108JQ7	(ABC) transporter
VagYM4_19310	ENOG4105C3U	ABC transporter
VagYM4_19320	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
VagYM4_19330	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
VagYM4_19340	ENOG4107QSI	ABC, transporter
VagYM4_19350	ENOG4108ZAF	Molybdopterin
VagYM4_19360	ENOG4105M00	molybdopterin converting factor, subunit 1
VagYM4_19370	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
VagYM4_19380	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
VagYM4_19390	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
VagYM4_19400	ENOG4105CHW	UPF0052 protein
VagYM4_19420	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
VagYM4_19430	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
VagYM4_19440	ENOG4105DGN	Electron transport complex
VagYM4_19450	ENOG4108R3D	Electron transport complex
VagYM4_19470	ENOG4105D6A	Electron transport complex
VagYM4_19480	ENOG4108UQQ	Electron transport complex
VagYM4_19490	ENOG4105DZB	Electron transport complex
VagYM4_19500	ENOG4105CSM	endonuclease III
VagYM4_19510	ENOG4108UYE	Lactoylglutathione lyase
VagYM4_19520	ENOG4106WH9	Protein of unknown function (DUF2753)
VagYM4_19530	ENOG4105EIY	sodium-type flagellar protein motY
VagYM4_19550	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
VagYM4_19560	ENOG4105D3Y	Na H antiporter
VagYM4_19580	ENOG4105M2J	Glutaredoxin
VagYM4_19590	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
VagYM4_19620	ENOG4105C0A	alcohol dehydrogenase
VagYM4_19630	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
VagYM4_19640	ENOG4105EYW	Ion transport protein
VagYM4_19650	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
VagYM4_19660	ENOG4105DFD	Na H antiporter
VagYM4_19690	ENOG4106V8H	Nucleoid-associated protein
VagYM4_19700	ENOG4105YDX	UPF0352 protein
VagYM4_19710	ENOG4105E68	Sulfatase
VagYM4_19720	ENOG4105DGU	Histone deacetylase
VagYM4_19730	ENOG4108RU0	short-chain dehydrogenase reductase
VagYM4_19750	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
VagYM4_19760	ENOG41069NU	Nitroreductase
VagYM4_19780	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
VagYM4_19790	ENOG4105D07	Signal peptide peptidase, SppA
VagYM4_19800	ENOG4105HDK	L-asparaginase
VagYM4_19810	ENOG4105VUT	cytoplasmic protein
VagYM4_19830	ENOG4105E0X	reductase
VagYM4_19840	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
VagYM4_19850	ENOG4105DSB	aldose 1-epimerase
VagYM4_19860	ENOG4105C8Q	Methyl-accepting chemotaxis
VagYM4_19870	ENOG4105DHI	Methyltransferase
VagYM4_19900	ENOG4105G6Z	alkaline phosphatase
VagYM4_19920	ENOG4108UYE	Lactoylglutathione lyase
VagYM4_19930	ENOG41067V3	Antibiotic biosynthesis monooxygenase
VagYM4_19950	ENOG4108ZZ3	UPF0260 protein
VagYM4_19960	ENOG4105Y3U	Transglycosylase-associated protein
VagYM4_19970	ENOG4105KRS	Proteinase inhibitor
VagYM4_19990	ENOG4105CEM	UPF0597 protein
VagYM4_20000	ENOG4105KME	endoribonuclease L-psp
VagYM4_20010	ENOG4105C44	Serine transporter
VagYM4_20020	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
VagYM4_20030	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
VagYM4_20040	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
VagYM4_20050	ENOG4107QMP	dna polymerase iii subunits gamma and tau
VagYM4_20060	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
VagYM4_20070	ENOG4105WD1	Membrane
VagYM4_20090	ENOG4105I93	response regulator
VagYM4_20100	ENOG4105EJC	lysr family transcriptional regulator
VagYM4_20110	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
VagYM4_20120	ENOG4105E96	Colicin v production protein
VagYM4_20130	ENOG4108S3P	Sporulation domain protein
VagYM4_20140	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
VagYM4_20150	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
VagYM4_20160	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
VagYM4_20180	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
VagYM4_20190	ENOG4105CJ0	Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate (By similarity)
VagYM4_20200	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
VagYM4_20210	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
VagYM4_20220	ENOG4105Q8W	reductase
VagYM4_20230	ENOG4105MH2	YfcL protein
VagYM4_20240	ENOG4108BPE	-transporting atpase
VagYM4_20250	ENOG4105EN6	Membrane
VagYM4_20260	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
VagYM4_20270	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
VagYM4_20280	ENOG4108DG9	Smr protein MutS2
VagYM4_20290	ENOG4108BY2	phosphohistidine phosphatase
VagYM4_20300	ENOG4107QXK	peptidase
VagYM4_20320	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
VagYM4_20330	ENOG4105CHU	acetyl-coa acetyltransferase
VagYM4_20360	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
VagYM4_20370	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
VagYM4_20380	ENOG410903C	(LipO)protein
VagYM4_20390	ENOG4105KWW	Biogenesis protein
VagYM4_20400	ENOG4108M1T	Cytochrome c-type biogenesis protein
VagYM4_20410	ENOG4107QX9	Thiol disulfide interChange protein
VagYM4_20420	ENOG4105DA4	cytochrome c-type biogenesis protein
VagYM4_20430	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
VagYM4_20440	ENOG4105X3C	heme exporter protein
VagYM4_20450	ENOG41060IM	Heme exporter protein
VagYM4_20460	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
VagYM4_20470	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
VagYM4_20490	ENOG4108V3W	Chemotaxis protein, CheW
VagYM4_20510	ENOG4107QJE	Chromosome Partitioning Protein
VagYM4_20520	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
VagYM4_20540	ENOG4108KCC	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity)
VagYM4_20550	ENOG4108VYJ	response regulator receiver protein
VagYM4_20560	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
VagYM4_20580	ENOG4105FZW	flagellar biosynthesis regulator FlhF
VagYM4_20590	ENOG4105D7B	Flagellar biosynthesis protein flha
VagYM4_20600	ENOG4105D00	flagellar biosynthetic protein flhB
VagYM4_20610	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
VagYM4_20620	ENOG4105VS8	Flagellar biosynthetic protein fliq
VagYM4_20630	ENOG4105CN7	Flagellar biosynthetic protein FliP
VagYM4_20640	ENOG4105VTB	flagellar biosynthesis protein fliO
VagYM4_20650	ENOG4105DD5	Flagellar motor switch protein
VagYM4_20660	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
VagYM4_20700	ENOG4108JIR	Flagellum-specific ATP synthase
VagYM4_20720	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
VagYM4_20730	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
VagYM4_20740	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
VagYM4_20760	ENOG4105BZU	Histidine kinase
VagYM4_20780	ENOG4105MQ3	flagellar protein FliS
VagYM4_20800	ENOG4107BRV	flagellar capping protein
VagYM4_20810	ENOG41063QE	flagellar protein FlaG
VagYM4_20820	ENOG4105I03	Flagellin
VagYM4_20830	ENOG4105I03	Flagellin
VagYM4_20840	ENOG4105I03	Flagellin
VagYM4_20850	ENOG4105EZR	dyp-type peroxidase family protein
VagYM4_20860	ENOG4105QZU	Inner membrane protein YfeZ
VagYM4_20900	ENOG4105KUZ	arsenate reductase
VagYM4_20910	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
VagYM4_20940	ENOG4107EG0	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
VagYM4_20970	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
VagYM4_21000	ENOG4105ERG	peptidase m48, ste24p
VagYM4_21010	ENOG4105K89	arsenate reductase
VagYM4_21020	ENOG4105CS1	NAD(P)H quinone oxidoreductase
VagYM4_21050	ENOG4105C2W	permease
VagYM4_21060	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
VagYM4_21070	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
VagYM4_21080	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
VagYM4_21090	ENOG4105E7A	Glutamine amidotransferase
VagYM4_21100	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
VagYM4_21110	ENOG4107QPN	acyl-Coa dehydrogenase
VagYM4_21170	ENOG4107RZZ	dna polymerase iii epsilon subunit
VagYM4_21180	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
VagYM4_21190	ENOG4105D1A	Methyltransferase
VagYM4_21200	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
VagYM4_21210	ENOG4105E9H	Lytic Murein transglycosylase
VagYM4_21230	ENOG4107NA1	Endonuclease Exonuclease phosphatase
VagYM4_21240	ENOG4108YZA	Nitrogen regulatory protein pii
VagYM4_21250	ENOG4105N7H	Cytochrome
VagYM4_21260	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
VagYM4_21270	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
VagYM4_21280	ENOG4105C0B	DNA polymerase III (alpha subunit)
VagYM4_21290	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
VagYM4_21300	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
VagYM4_21310	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
VagYM4_21320	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
VagYM4_21330	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
VagYM4_21340	ENOG4108RFI	Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm (By similarity)
VagYM4_21360	ENOG4105DZP	Membrane-associated zinc metalloprotease
VagYM4_21370	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
VagYM4_21380	ENOG4105KNE	Phosphatidate cytidylyltransferase
VagYM4_21390	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
VagYM4_21400	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
VagYM4_21410	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
VagYM4_21420	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
VagYM4_21430	ENOG4105CE9	30S ribosomal protein S2
VagYM4_21440	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
VagYM4_21450	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
VagYM4_21460	ENOG4108T8E	UPF0325 protein
VagYM4_21470	ENOG4105DR9	pseudouridine synthase
VagYM4_21480	ENOG4105DR9	pseudouridine synthase
VagYM4_21530	ENOG4108UPT	UPF0178 protein
VagYM4_21540	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
VagYM4_21550	ENOG4107VBM	3-beta hydroxysteroid dehydrogenase isomerase
VagYM4_21600	ENOG4105CFC	Transporter
VagYM4_21610	ENOG4105NRA	50s ribosomal protein l31 type b
VagYM4_21620	ENOG4108R96	Methyltransferase, YaeB family
VagYM4_21630	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
VagYM4_21650	ENOG4105W1I	UPF0253 protein
VagYM4_21670	ENOG4105C8J	)-transporter
VagYM4_21700	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
VagYM4_21710	ENOG4105C9U	ATP-dependent DNA helicase RecQ
VagYM4_21720	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
VagYM4_21750	ENOG4105CJ2	(LipO)protein
VagYM4_21760	ENOG4105D26	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway (By similarity)
VagYM4_21770	ENOG4108IUB	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
VagYM4_21780	ENOG4105F5D	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
VagYM4_21790	ENOG4106I92	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
VagYM4_21800	ENOG4108J5C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
VagYM4_21810	ENOG4105DWQ	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
VagYM4_21820	ENOG4105M85	Bola protein
VagYM4_21830	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
VagYM4_21840	ENOG4105IEY	(LipO)protein
VagYM4_21850	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
VagYM4_21880	ENOG4105K6V	RNA polymerase
VagYM4_21920	ENOG4108JZF	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
VagYM4_21930	ENOG4107S0N	DJ-1 family
VagYM4_21940	ENOG4105C9B	Cysteine desulfurase
VagYM4_21950	ENOG4105BZU	Histidine kinase
VagYM4_21970	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
VagYM4_21980	ENOG4105CUZ	uba thif-type nad fad binding protein
VagYM4_21990	ENOG4105CA3	membrane-bound lytic murein transglycosylase
VagYM4_22010	ENOG4107QZM	n-acetylglutamate synthase
VagYM4_22050	ENOG4107QYX	exodeoxyribonuclease v alpha
VagYM4_22060	ENOG4107QKA	exodeoxyribonuclease V beta
VagYM4_22070	ENOG4105DSY	exodeoxyribonuclease V, gamma
VagYM4_22080	ENOG4105E68	Sulfatase
VagYM4_22100	ENOG4105EVZ	LysR family transcriptional regulator
VagYM4_22110	ENOG4105X2V	dna damage-inducible protein
VagYM4_22120	ENOG4105EJ3	Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA (By similarity)
VagYM4_22130	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
VagYM4_22140	ENOG4105CXY	transporter
VagYM4_22150	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
VagYM4_22160	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
VagYM4_22170	ENOG4105E98	transcriptional regulator DeoR family
VagYM4_22180	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
VagYM4_22220	ENOG4108Y51	tRNA-binding protein
VagYM4_22230	ENOG41060NJ	transcriptional regulator
VagYM4_22240	ENOG4105CT4	transporter
VagYM4_22260	ENOG4105ETE	Transcriptional regulator (LacI family
VagYM4_22270	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
VagYM4_22280	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
VagYM4_22290	ENOG4105F0Z	galactose-1-phosphate uridylyltransferase
VagYM4_22300	ENOG4105CMR	udp-glucose 4-epimerase
VagYM4_22310	ENOG4105CQ4	Transcriptional regulator
VagYM4_22320	ENOG4105CNT	hydrolase family 2
VagYM4_22330	ENOG4105FK9	beta-D-galactosidase beta subunit
VagYM4_22340	ENOG4105E5D	amino acid
VagYM4_22350	ENOG41064T2	transcriptional regulator, lysR family
VagYM4_22530	ENOG4108IQE	Amp-dependent synthetase and ligase
VagYM4_22550	ENOG4105ETT	transcriptional Regulator, LysR family
VagYM4_22560	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
VagYM4_22570	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
VagYM4_22590	ENOG4105EAC	phosphoserine phosphatase
VagYM4_22610	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
VagYM4_22620	ENOG4105CZG	Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity)
VagYM4_22630	ENOG4105CMW	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity)
VagYM4_22640	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
VagYM4_22650	ENOG4105D9N	nucleoside
VagYM4_22660	ENOG4105EYA	deoxyribonuclease
VagYM4_22680	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
VagYM4_22830	ENOG4105D2N	Aldolase
VagYM4_22880	ENOG4105D0M	Protease HtpX homolog
VagYM4_22910	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
VagYM4_22940	ENOG4105CFG	Acts as a chaperone (By similarity)
VagYM4_22950	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
VagYM4_22980	ENOG4105VN1	Heat shock protein
VagYM4_22990	ENOG4105VN1	Heat shock protein
VagYM4_23010	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
VagYM4_23110	ENOG4108YGG	dna repair protein
VagYM4_23160	ENOG4105GMT	ATPase associated with various cellular activities aaa_5
VagYM4_23200	ENOG4108UUM	single-stranded DNA-binding protein
VagYM4_23240	ENOG4105VNT	transposase (IS4 family) protein
VagYM4_23260	ENOG4105EKQ	RNA-directed DNA polymerase
VagYM4_23290	ENOG4105D64	Mechanosensitive ion channel
VagYM4_23300	ENOG4105C94	Transporter
VagYM4_23420	ENOG4105T95	Thiol disulfide interChange protein
VagYM4_23660	ENOG4105KT5	UmuD protein
VagYM4_23670	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
VagYM4_23780	ENOG4108YYD	acetyltransferase
VagYM4_23800	ENOG4105BZU	Histidine kinase
VagYM4_23830	ENOG4105C3S	Mate efflux family protein
VagYM4_23860	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
VagYM4_23870	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
VagYM4_23880	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
VagYM4_23890	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
VagYM4_23900	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
VagYM4_23910	ENOG4105CHV	Transcription elongation factor NusA
VagYM4_23920	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
VagYM4_23930	ENOG4105NTZ	Preprotein translocase subunit SecG
VagYM4_23940	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
VagYM4_23950	ENOG4105EEI	dihydropteroate synthase
VagYM4_23960	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
VagYM4_23970	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
VagYM4_23980	ENOG4105HBR	Rna-binding protein
VagYM4_23990	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
VagYM4_24000	ENOG4107QE9	Inherit from COG: Membrane
VagYM4_24010	ENOG4106HRJ	d-alanyl-d-alanine carboxypeptidase
VagYM4_24030	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
VagYM4_24040	ENOG4105DR5	peptidase
VagYM4_24070	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
VagYM4_24080	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
VagYM4_24090	ENOG4105F4G	Membrane
VagYM4_24100	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
VagYM4_24120	ENOG4107QRA	Extracellular solute-binding protein, family 5
VagYM4_24140	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
VagYM4_24150	ENOG4105C3U	ABC transporter
VagYM4_24160	ENOG4108JQ7	(ABC) transporter
VagYM4_24180	ENOG4105RD7	BadF BadG BcrA BcrD
VagYM4_24190	ENOG4105E2D	ec 3.2.1.52
VagYM4_24220	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
VagYM4_24270	ENOG4105XTV	UPF0231 protein
VagYM4_24280	ENOG4107QIJ	Aconitate hydratase 2
VagYM4_24290	ENOG4105D78	K07001 NTE family protein
VagYM4_24300	ENOG4105BZ4	penicillin-binding protein
VagYM4_24310	ENOG4105CQ7	ATP-dependent helicase
VagYM4_24320	ENOG4105PW4	Sugar fermentation stimulation protein homolog
VagYM4_24330	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
VagYM4_24340	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
VagYM4_24350	ENOG4105DJ0	Poly(A) Polymerase
VagYM4_24360	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
VagYM4_24370	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
VagYM4_24380	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
VagYM4_24390	ENOG4105D1S	lipid A biosynthesis
VagYM4_24400	ENOG4105E3A	(ABC) transporter
VagYM4_24410	ENOG4105DA5	(ABC) transporter
VagYM4_24420	ENOG4105CHH	sulfate transporter
VagYM4_24430	ENOG41077A9	carbonic anhydrase
VagYM4_24440	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
VagYM4_24450	ENOG410630P	Transcriptional regulator
VagYM4_24460	ENOG4107QN2	dihydrolipoyl dehydrogenase
VagYM4_24470	ENOG4107QSN	dihydrolipoamide acetyltransferase
VagYM4_24480	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
VagYM4_24490	ENOG41073TP	transcriptional regulator
VagYM4_24510	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
VagYM4_24520	ENOG4105X0D	Fimbrial protein
VagYM4_24530	ENOG4107QHF	type ii secretion system protein e
VagYM4_24540	ENOG4105D7Q	type ii secretion system
VagYM4_24550	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
VagYM4_24560	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
VagYM4_24570	ENOG4105DHA	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity (By similarity)
VagYM4_24580	ENOG41067SF	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity)
VagYM4_24590	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
VagYM4_24600	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
VagYM4_24610	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
VagYM4_24620	ENOG4105K5M	30s ribosomal protein S16
VagYM4_24630	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
VagYM4_24640	ENOG4106KVJ	cytochrome C assembly protein
VagYM4_24650	ENOG4108JU6	CBS domain protein
VagYM4_24680	ENOG4105D9M	gamma-glutamylcysteine synthetase
VagYM4_24700	ENOG4105W39	Membrane
VagYM4_24720	ENOG4105D9Q	decarboxylase (Beta subunit)
VagYM4_24730	ENOG4107QSA	Oxaloacetate decarboxylase
VagYM4_24750	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
VagYM4_24760	ENOG4105CFH	Aspartokinase
VagYM4_24770	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
VagYM4_24780	ENOG4105Y3E	Modulates RecA activity (By similarity)
VagYM4_24790	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
VagYM4_24800	ENOG4107TH8	cina domain protein
VagYM4_24810	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
VagYM4_24820	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
VagYM4_24840	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
VagYM4_24850	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
VagYM4_24860	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
VagYM4_24870	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
VagYM4_24880	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
VagYM4_24890	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
VagYM4_24900	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
VagYM4_24910	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
VagYM4_24920	ENOG4105DXN	mazG family
VagYM4_24930	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
VagYM4_24940	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
VagYM4_24950	ENOG4105BZU	Histidine kinase
VagYM4_24960	ENOG4105KJV	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
VagYM4_24970	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
VagYM4_24980	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
VagYM4_24990	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
VagYM4_25000	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
VagYM4_25010	ENOG4105C3F	Signal peptidase i
VagYM4_25020	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
VagYM4_25060	ENOG4105EMN	RNA polymerase sigma factor
VagYM4_25070	ENOG4108IYU	L-aspartate oxidase
VagYM4_25090	ENOG4105Y75	tpr repeat protein
VagYM4_25100	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
VagYM4_25130	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
VagYM4_25140	ENOG4105D0A	hydroxylase
VagYM4_25160	ENOG4107YUN	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
VagYM4_25170	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
VagYM4_25180	ENOG4105E66	phosphoriboisomerase A
VagYM4_25190	ENOG4108JQ1	Dehydrogenase
VagYM4_25200	ENOG4105MPN	Membrane
VagYM4_25210	ENOG4105CXD	Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity)
VagYM4_25240	ENOG4105D64	Mechanosensitive ion channel
VagYM4_25250	ENOG4105D2N	Aldolase
VagYM4_25260	ENOG4105BZA	Phosphoglycerate kinase
VagYM4_25270	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
VagYM4_25280	ENOG4105D05	Receptor
VagYM4_25290	ENOG4108R4R	Iron-regulated virulence regulatory protein
VagYM4_25300	ENOG4105CV1	Transketolase (EC 2.2.1.1)
VagYM4_25310	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
VagYM4_25330	ENOG4105GPY	SprT protein
VagYM4_25340	ENOG4105RWS	endonuclease I
VagYM4_25350	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
VagYM4_25360	ENOG4105D7Z	glutathione synthase
VagYM4_25370	ENOG4108UJU	UPF0301 protein
VagYM4_25380	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
VagYM4_25390	ENOG4105CZX	twitching motility protein
VagYM4_25400	ENOG4105CZX	twitching motility protein
VagYM4_25410	ENOG4105DFA	alanine racemase domain protein
VagYM4_25420	ENOG4105II7	pyrroline-5-carboxylate reductase
VagYM4_25430	ENOG4108VIA	integral membrane protein
VagYM4_25440	ENOG4105VZ9	UPF0235 protein
VagYM4_25460	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
VagYM4_25470	ENOG4105CSA	Coproporphyrinogen iii oxidase
VagYM4_25480	ENOG4105CSV	Glutaminase
VagYM4_25500	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
VagYM4_25510	ENOG4105CEN	a g-specific adenine glycosylase
VagYM4_25520	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
VagYM4_25540	ENOG4105C8Q	Methyl-accepting chemotaxis
VagYM4_25560	ENOG4108ESY	Metal dependent phosphohydrolase
VagYM4_25580	ENOG410901P	UPF0249 protein
VagYM4_25590	ENOG4105F8D	glycoside hydrolase family 4
VagYM4_25600	ENOG4105VCP	PTS System
VagYM4_25610	ENOG4105CK1	PTS System
VagYM4_25620	ENOG4105VZJ	PTS System
VagYM4_25640	ENOG4105BZU	Histidine kinase
VagYM4_25650	ENOG4105EQR	Transposase IS116 IS110 IS902
VagYM4_25660	ENOG4105EQR	Transposase IS116 IS110 IS902
VagYM4_25940	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
VagYM4_25970	ENOG4108K5H	permease YjgP YjgQ family protein
VagYM4_25980	ENOG4108M8S	permease YjgP YjgQ family protein
VagYM4_25990	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
VagYM4_26000	ENOG4105MYG	DNA polymerase iii, chi subunit
VagYM4_26010	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
VagYM4_26030	ENOG4108MJ3	acetyltransferase
VagYM4_26060	ENOG4105CEU	Arginine dihydrolase
VagYM4_26070	ENOG4105DBV	ornithine carbamoyltransferase
VagYM4_26090	ENOG4105CXT	aspartate transcarbamylase
VagYM4_26100	ENOG4108R9M	Involved in allosteric regulation of aspartate carbamoyltransferase (By similarity)
VagYM4_26110	ENOG4105KME	endoribonuclease L-psp
VagYM4_26120	ENOG4107S7E	1-acyl-sn-glycerol-3-phosphate acyltransferase
VagYM4_26130	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
VagYM4_26140	ENOG4105VFK	BolA family
VagYM4_26160	ENOG4105E3I	toluene tolerance
VagYM4_26170	ENOG4107PE3	Mammalian cell entry related domain protein
VagYM4_26180	ENOG4105CY3	ABC transporter, permease
VagYM4_26190	ENOG4105DHJ	ABC, transporter
VagYM4_26210	ENOG4105C2X	Arabinose 5-phosphate isomerase
VagYM4_26230	ENOG4105WI0	lipopolysaccharide transport periplasmic protein lptA
VagYM4_26240	ENOG4108IUZ	ABC transporter
VagYM4_26250	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
VagYM4_26260	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
VagYM4_26270	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
VagYM4_26280	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
VagYM4_26290	ENOG41080Z8	PHOSPHOCARRIER protein
VagYM4_26300	ENOG4105CJW	magnesium transporter
VagYM4_26310	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
VagYM4_26320	ENOG4105N42	UPF0307 protein
VagYM4_26330	ENOG4105C5I	Dehydrogenase
VagYM4_26340	ENOG4105D3G	Pseudouridine synthase
VagYM4_26350	ENOG4105K3M	)-transporter
VagYM4_26360	ENOG4105BZK	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity)
VagYM4_26370	ENOG4108IAB	Phoh family
VagYM4_26380	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
VagYM4_26400	ENOG4105QD6	exported protein
VagYM4_26410	ENOG4105C03	ribonuclease
VagYM4_26420	ENOG4108Z03	MAF-like protein
VagYM4_26430	ENOG4105VQ7	Rod shape-determining protein MreD
VagYM4_26440	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
VagYM4_26540	ENOG4105D7Q	type ii secretion system
VagYM4_26550	ENOG4107QHF	type ii secretion system protein e
VagYM4_26620	ENOG41062P1	Diguanylate cyclase phosphodiesterase
VagYM4_26630	ENOG4105EKQ	RNA-directed DNA polymerase
VagYM4_26640	ENOG4108UUM	single-stranded DNA-binding protein
VagYM4_26650	ENOG41086KC	Transcriptional regulator
VagYM4_26660	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
VagYM4_26670	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
VagYM4_26690	ENOG4105C5R	Aminotransferase
VagYM4_26700	ENOG4105CFH	Aspartokinase
VagYM4_26710	ENOG4105C3R	Methionine synthase
VagYM4_26720	ENOG4105EEQ	Na H antiporter
VagYM4_26750	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
VagYM4_26760	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
VagYM4_26770	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
VagYM4_26810	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
VagYM4_26840	ENOG4108ZUB	Lysine exporter protein (Lyse ygga)
VagYM4_26860	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
VagYM4_26870	ENOG4108KJ0	anaerobic glycerol-3-phosphate dehydrogenase, subunit B
VagYM4_26880	ENOG4107R5Y	anaerobic glycerol-3-phosphate dehydrogenase, subunit A
VagYM4_27020	ENOG4105MYN	Zinc uptake regulation protein
VagYM4_27040	ENOG4107QP8	phosphohexose isomerase
VagYM4_27060	ENOG4108YXI	Secondary thiamine-phosphate synthase enzyme
VagYM4_27070	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
VagYM4_27080	ENOG4105CDU	Replicative dna helicase
VagYM4_27100	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
VagYM4_27110	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
VagYM4_27120	ENOG4108VDV	Binds single-stranded DNA at the primosome assembly site (PAS) (By similarity)
VagYM4_27130	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
VagYM4_27140	ENOG4105DJV	ribulose-phosphate 3-epimerase
VagYM4_27150	ENOG4105DFE	Dna adenine methylase
VagYM4_27170	ENOG4105D49	3-dehydroquinate synthase
VagYM4_27180	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
VagYM4_27190	ENOG4105E4G	Type IV pilus
VagYM4_27240	ENOG4108JQC	penicillin-binding protein 1A
VagYM4_27250	ENOG4105C5Q	Transcriptional regulator
VagYM4_27260	ENOG4105EHV	domain protein
VagYM4_27270	ENOG4107QN2	dihydrolipoyl dehydrogenase
VagYM4_27300	ENOG4105CH7	arginosuccinase
VagYM4_27310	ENOG4105CDH	Citrulline--aspartate ligase
VagYM4_27320	ENOG4105CAS	nag kinase
VagYM4_27330	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
VagYM4_27340	ENOG4105CWC	Acetylornithine deacetylase
VagYM4_27350	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
VagYM4_27370	ENOG4105SYT	Methylenetetrahydrofolate reductase
VagYM4_27380	ENOG4105CFH	Aspartokinase
VagYM4_27390	ENOG4105C28	cystathionine
VagYM4_27400	ENOG4105GGQ	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis (By similarity)
VagYM4_27410	ENOG4105C6K	Malic enzyme
VagYM4_27420	ENOG4108UQY	Iron-storage protein
VagYM4_27430	ENOG4105W53	bacterioferritin-associated ferredoxin
VagYM4_27440	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
VagYM4_27450	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
VagYM4_27460	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
VagYM4_27470	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
VagYM4_27490	ENOG4108ZKU	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (By similarity)
VagYM4_27500	ENOG4108ZAT	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE (By similarity)
VagYM4_27510	ENOG4105WWK	YheO domain protein
VagYM4_27520	ENOG4108V1T	peptidylprolyl cis-trans isomerase
VagYM4_27540	ENOG41069P5	Protein slyX homolog
VagYM4_27550	ENOG4105D44	asparaginase
VagYM4_27560	ENOG4108YZY	peptidylprolyl cis-trans isomerase
VagYM4_27590	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
VagYM4_27600	ENOG4105C5H	ABC transporter
VagYM4_27620	ENOG4105DNZ	Alpha Beta Hydrolase
VagYM4_27630	ENOG4105YP7	UPF0270 protein
VagYM4_27640	ENOG4105CJE	phosphoribulokinase (EC 2.7.1.19)
VagYM4_27670	ENOG4105C26	Dehydrogenase
VagYM4_27690	ENOG4105C8Y	Acetylornithine aminotransferase
VagYM4_27700	ENOG4105DDQ	anthranilate synthase
VagYM4_27730	ENOG4105C31	Tryptophanyl-tRNA synthetase
VagYM4_27740	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
VagYM4_27750	ENOG4105C2N	RNA methyltransferase TrmH family group 3
VagYM4_27760	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
VagYM4_27770	ENOG4105KPV	Transcriptional regulator
VagYM4_27780	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
VagYM4_27790	ENOG4108UV7	flagellar protein motX
VagYM4_27800	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
VagYM4_27820	ENOG4105EPW	hflc protein
VagYM4_27830	ENOG4107QJR	hflk protein
VagYM4_27840	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
VagYM4_27850	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
VagYM4_27860	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
VagYM4_27870	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
VagYM4_27880	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
VagYM4_27890	ENOG4105K8N	protein family UPF0079, ATPase
VagYM4_27900	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
VagYM4_27910	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
VagYM4_27920	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
VagYM4_27930	ENOG4105DJ4	phosphatidylserine decarboxylase
VagYM4_27960	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
VagYM4_27970	ENOG4107YZP	Rhodanese domain protein
VagYM4_27980	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
VagYM4_27990	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
VagYM4_28000	ENOG4105D7W	serine acetyltransferase
VagYM4_28010	ENOG41063SB	peptidase
VagYM4_28030	ENOG41062JF	Transcriptional regulator
VagYM4_28050	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
VagYM4_28070	ENOG4105E33	succinate dehydrogenase
VagYM4_28080	ENOG4108WJH	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity)
VagYM4_28090	ENOG4108VP9	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity)
VagYM4_28110	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
VagYM4_28120	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
VagYM4_28130	ENOG4105KT7	mgtC SapB transporter
VagYM4_28150	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
VagYM4_28160	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
VagYM4_28180	ENOG4105CTQ	phosphohexokinase
VagYM4_28190	ENOG41076HS	cation diffusion facilitator family transporter
VagYM4_28210	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
VagYM4_28220	ENOG4105E0F	Histidine kinase
VagYM4_28240	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
VagYM4_28250	ENOG4108YH1	overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7
VagYM4_28260	ENOG4108IJ0	Aspartate ammonia-lyase
VagYM4_28270	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
VagYM4_28280	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
VagYM4_28300	ENOG4105C3N	Participates in control of cell volume in low-osmolarity conditions (By similarity)
VagYM4_28320	ENOG4107QN1	sodium solute
VagYM4_28350	ENOG4105C9Q	fumarate hydratase class II
VagYM4_28360	ENOG4105BZU	Histidine kinase
VagYM4_28370	ENOG4105D8G	Major Facilitator superfamily
VagYM4_28400	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
VagYM4_28410	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
VagYM4_28420	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
VagYM4_28430	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
VagYM4_28440	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
VagYM4_28450	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
VagYM4_28460	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
VagYM4_28480	ENOG4105C5H	ABC transporter
VagYM4_28490	ENOG4105CXN	decarboxylase
VagYM4_28500	ENOG4105D5Q	Arginine ornithine antiporter
VagYM4_28520	ENOG4108M3R	transcriptional activator CadC
VagYM4_28530	ENOG4105W1Y	Transcriptional regulator
VagYM4_28540	ENOG4105DC1	bifunctional purine biosynthesis protein purh
VagYM4_28550	ENOG4105C12	Phosphoribosylglycinamide synthetase
VagYM4_28590	ENOG4105R2J	Conserved Protein
VagYM4_28600	ENOG4105JPG	D-isomer specific 2-hydroxyacid dehydrogenase
VagYM4_28610	ENOG4108RG0	uracil-dna glycosylase
VagYM4_28620	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
VagYM4_28630	ENOG4105E09	nadh pyrophosphatase
VagYM4_28640	ENOG4108ZVW	Anti-RNA polymerase sigma 70 factor
VagYM4_28650	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
VagYM4_28660	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
VagYM4_28670	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
VagYM4_28680	ENOG4108VZM	50s ribosomal protein L10
VagYM4_28690	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
VagYM4_28700	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
VagYM4_28710	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
VagYM4_28720	ENOG4105PM1	preprotein translocase subunit SecE
VagYM4_28730	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
VagYM4_28740	ENOG4105CS9	pantothenic acid kinase
VagYM4_28750	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
VagYM4_28760	ENOG4105D4A	Cell wall formation (By similarity)
VagYM4_28780	ENOG4105JIM	Phosphatidylserine synthase
VagYM4_28800	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
VagYM4_28820	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
VagYM4_28830	ENOG4107R9T	Catalyzes the formation of 5-methyl-uridine at position 54 (m5U54) in all tRNAs (By similarity)
VagYM4_28860	ENOG4105DX1	Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation (By similarity)
VagYM4_28870	ENOG4107R73	Mate efflux family protein
VagYM4_28890	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
VagYM4_28900	ENOG4105E55	glycerol-3-phosphate acyltransferase
VagYM4_28910	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
VagYM4_28920	ENOG4105VEI	Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway (By similarity)
VagYM4_28930	ENOG4105X6C	Flagellar basal body-associated protein FliL
VagYM4_28940	ENOG4105EBW	Rhomboid-type serine protease that catalyzes intramembrane proteolysis (By similarity)
VagYM4_28950	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
VagYM4_28960	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
VagYM4_28970	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
VagYM4_28980	ENOG4105CAK	Cell division ATP-binding protein ftsE
VagYM4_28990	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
VagYM4_29000	ENOG4106H78	methyltransferase
VagYM4_29020	ENOG41076UM	multiple antibiotic resistance (MarC)-related protein
VagYM4_29110	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
VagYM4_29120	ENOG41082YX	Transcriptional regulator, arsr family
VagYM4_29130	ENOG4105D58	Diguanylate phosphodiesterase
VagYM4_29140	ENOG410829K	Lysine exporter protein (Lyse ygga)
VagYM4_29150	ENOG4108EUD	Lysophospholipase
VagYM4_29160	ENOG4105DQF	Hydrolase
VagYM4_29190	ENOG4106IUH	DTW domain containing protein
VagYM4_29200	ENOG4105BZU	Histidine kinase
VagYM4_29210	ENOG4105DFC	had-superfamily hydrolase, subfamily ia, variant
VagYM4_29220	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
VagYM4_29240	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
VagYM4_29250	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
VagYM4_29260	ENOG4105XQ6	frataxin-like protein
VagYM4_29280	ENOG4107T0K	Adenylate cyclase
VagYM4_29290	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
VagYM4_29300	ENOG41076E6	Uroporphyrinogen-III Synthase
VagYM4_29310	ENOG4105ECF	c-methyltransferase
VagYM4_29320	ENOG410601J	HemY protein
VagYM4_29330	ENOG4107QK7	reductase
VagYM4_29340	ENOG4108ZIT	Ferredoxin, 2FE-2S
VagYM4_29350	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
VagYM4_29370	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
VagYM4_29390	ENOG4105C1J	atp-dependent rna helicase
VagYM4_29400	ENOG4105C9X	ppx gppa phosphatase
VagYM4_29410	ENOG4105EX9	Membrane
VagYM4_29430	ENOG4105C9U	ATP-dependent DNA helicase RecQ
VagYM4_29440	ENOG4105FR1	rard protein
VagYM4_29460	ENOG4105CCF	Lysine exporter protein (Lyse ygga)
VagYM4_29470	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
VagYM4_29490	ENOG4105C4R	Atp-dependent dna helicase
VagYM4_29510	ENOG4105E18	UPF0276 protein
VagYM4_29560	ENOG4105G2Y	Transcriptional regulator
VagYM4_29570	ENOG4105DC7	peptidase M24
VagYM4_29570	ENOG4105DC7	peptidase M24
VagYM4_29580	ENOG4105D41	biosynthesis protein thiH
VagYM4_29590	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
VagYM4_29610	ENOG4105D06	uba thif-type nad fad binding protein
VagYM4_29630	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
VagYM4_29640	ENOG4105WMR	Protein CrcB homolog
VagYM4_29650	ENOG4105E3B	Multicopper oxidase
VagYM4_29660	ENOG4108Z0R	Transferase
VagYM4_29670	ENOG4105SG3	Protein of unknown function (DUF1488)
VagYM4_29680	ENOG4105E2X	shikimate dehydrogenase
VagYM4_29690	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
VagYM4_29700	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
VagYM4_29710	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
VagYM4_29720	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
VagYM4_29730	ENOG4108WI1	Dna topoisomerase
VagYM4_29740	ENOG4108RPN	Protein smg homolog
VagYM4_29750	ENOG4105C79	DNA protecting protein DprA
VagYM4_29770	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
VagYM4_29780	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
VagYM4_29790	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
VagYM4_29800	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
VagYM4_29810	ENOG4105C1A	potassium transporter peripheral membrane
VagYM4_29820	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
VagYM4_29840	ENOG4108UT2	hemolysin iii
VagYM4_29850	ENOG4108N23	SpoOM-related protein
VagYM4_29870	ENOG4105PC1	Conserved Protein
VagYM4_29890	ENOG4105E27	serine threonine protein kinase
VagYM4_29900	ENOG4108Z33	Thiol disulfide Interchange Protein
VagYM4_29910	ENOG4106HNH	Acyl-transferase
VagYM4_29930	ENOG4105C0P	Mg chelatase subunit ChlI
VagYM4_29950	ENOG4105P3Y	Acetolactate synthase 2 regulatory subunit
VagYM4_29960	ENOG4105CM2	brancheD-chain amino acid aminotransferase
VagYM4_29970	ENOG4105C01	Dihydroxy-acid dehydratase
VagYM4_29980	ENOG4105C7B	Threonine dehydratase
VagYM4_29990	ENOG4105F52	Transcriptional regulator
VagYM4_30000	ENOG4105CZQ	inner membrane transport protein YdhC
VagYM4_30010	ENOG4105F87	Dehydratase
VagYM4_30020	ENOG4105EAD	ABC transporter
VagYM4_30030	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
VagYM4_30040	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
VagYM4_30050	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
VagYM4_30060	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
VagYM4_30070	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
VagYM4_30080	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
VagYM4_30100	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
VagYM4_30110	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
VagYM4_30120	ENOG410684E	atp synthase
VagYM4_30130	ENOG4105FA0	parb-like partition protein
VagYM4_30140	ENOG4107QJE	Chromosome Partitioning Protein
VagYM4_30150	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
VagYM4_30160	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
VagYM4_30170	ENOG4105QTB	Flavodoxin
VagYM4_30190	ENOG4105BZU	Histidine kinase
VagYM4_30200	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
VagYM4_30210	ENOG4105F0Z	galactose-1-phosphate uridylyltransferase
VagYM4_30220	ENOG4105CMR	udp-glucose 4-epimerase
VagYM4_30230	ENOG4107RUZ	Sss sodium solute transporter superfamily
VagYM4_30250	ENOG4105ETE	Transcriptional regulator (LacI family
VagYM4_30460	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
VagYM4_30470	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
VagYM4_30480	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
VagYM4_30490	ENOG4105NVJ	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
VagYM4_30510	ENOG4105CDA	abc transporter atp-binding protein
VagYM4_30520	ENOG4105E5Q	amino acid AbC transporter
VagYM4_30530	ENOG4105EAB	amino acid AbC transporter
VagYM4_30560	ENOG4108JQ7	(ABC) transporter
VagYM4_30610	ENOG4105BZU	Histidine kinase
VagYM4_30630	ENOG4105CDY	transcriptional regulatory protein
VagYM4_30640	ENOG4105CNI	cell division protein FtsW
VagYM4_30660	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
VagYM4_30700	ENOG4108HRK	Histidine kinase
VagYM4_30710	ENOG4108VAC	response regulator
VagYM4_30730	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
VagYM4_30740	ENOG4105C8Q	Methyl-accepting chemotaxis
VagYM4_30770	ENOG4105D6U	Sodium Glutamate Symporter
VagYM4_30790	ENOG4105CZV	ABC transporter
VagYM4_30800	ENOG4107U9B	transcriptional regulator
VagYM4_30810	ENOG4105D6U	Sodium Glutamate Symporter
VagYM4_30830	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
VagYM4_30870	ENOG4105C2I	pirin domain protein
VagYM4_30880	ENOG4108VGI	doxx family
VagYM4_30900	ENOG4105D03	DNA-3-methyladenine glycosylase II
VagYM4_30910	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
VagYM4_30950	ENOG4105DN9	Na H antiporter
VagYM4_30990	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
VagYM4_31020	ENOG4105NBK	UPF0345 protein
VagYM4_31040	ENOG4105BZU	Histidine kinase
VagYM4_31050	ENOG4105UQX	Mate efflux family protein
VagYM4_31060	ENOG4105D3G	Pseudouridine synthase
VagYM4_31090	ENOG4105EJC	lysr family transcriptional regulator
VagYM4_31100	ENOG4108HCJ	Hydrolase
VagYM4_31120	ENOG4108KHX	Diguanylate cyclase
VagYM4_31160	ENOG4108MUX	N-hydroxyarylamine O-acetyltransferase
VagYM4_31170	ENOG4105CC0	LysR family Transcriptional regulator
VagYM4_31180	ENOG4105Q26	Siderophore-interacting protein
VagYM4_31210	ENOG4105EW9	transcriptional regulator AsnC family
VagYM4_31220	ENOG4108M1A	Chitin-binding protein
VagYM4_31250	ENOG4107W31	Pentapeptide repeat protein
VagYM4_31260	ENOG4105EIF	outer membrane protein W
VagYM4_31280	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
VagYM4_31320	ENOG4107WCA	isomerase
VagYM4_31330	ENOG4108UVJ	appr-1-p processing domain protein
VagYM4_31340	ENOG4109025	Glyoxalase Bleomycin resistance protein (Dioxygenase
VagYM4_31400	ENOG4108YZS	Had-superfamily hydrolase, subfamily ia, variant 1
VagYM4_31450	ENOG4108IXP	Carbohydrate diacid transcriptional activator CdaR
VagYM4_31460	ENOG4105C6Z	Gluconate
VagYM4_31470	ENOG4105BZW	Glycerate kinase
VagYM4_31480	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
VagYM4_31550	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
VagYM4_31560	ENOG41068WN	
VagYM4_31570	ENOG4105CUW	cytochrome C-TYPE protein
VagYM4_31580	ENOG4107QY8	reductase
VagYM4_31600	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
VagYM4_31610	ENOG4105C4U	4-methyl-5-beta-hydroxyethylthiazole kinase
VagYM4_31620	ENOG4105ETU	transcriptional activator (TenA
VagYM4_31630	ENOG4107Z6I	Thiamine biosynthesis protein
VagYM4_31640	ENOG4105Y36	Binding-protein-dependent transport systems, inner membrane component
VagYM4_31650	ENOG4108YI8	ABC transporter
VagYM4_31660	ENOG4105DWF	phosphomethylpyrimidine kinase
VagYM4_31690	ENOG4108TEM	pseudouridine methyltransferase
VagYM4_31730	ENOG4108YYI	Protein of unknown function (DUF2810)
VagYM4_31740	ENOG4105C5I	Dehydrogenase
VagYM4_31760	ENOG4107VXM	glycerophosphoryl diester phosphodiesterase
VagYM4_31780	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
VagYM4_31790	ENOG410804D	Sensor Signal Transduction Histidine Kinase
VagYM4_31840	ENOG4109015	Biopolymer transport protein exbD tolR
VagYM4_31930	ENOG4105DSE	periplasmic solute binding protein
VagYM4_31940	ENOG4105DIK	(ABC) transporter
VagYM4_31950	ENOG4105CC5	ABC transporter
VagYM4_31980	ENOG4105CUG	Oligopeptidase b
VagYM4_31990	ENOG4105E5M	Multidrug resistance protein D
VagYM4_32000	ENOG4105CYW	agmatinase
VagYM4_32010	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
VagYM4_32030	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
VagYM4_32040	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
VagYM4_32050	ENOG4105DUM	transcriptional regulator, lysR family
VagYM4_32140	ENOG4106TD9	Diguanylate cyclase
VagYM4_32150	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
VagYM4_32180	ENOG4105D5U	fad dependent oxidoreductase
VagYM4_32200	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
VagYM4_32210	ENOG4105C4M	(Ubiquinol oxidase) subunit I
VagYM4_32220	ENOG4108J5C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
VagYM4_32230	ENOG4105C0F	tryptophanase EC 4.1.99.1
VagYM4_32250	ENOG4105D9N	nucleoside
VagYM4_32280	ENOG4105BZU	Histidine kinase
VagYM4_32310	ENOG4106TD9	Diguanylate cyclase
VagYM4_32320	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
VagYM4_32330	ENOG4105EXX	Deoxyribodipyrimidine photolyase-related protein
VagYM4_32350	ENOG4105E0X	reductase
VagYM4_32360	ENOG4108UKZ	OsmC family
VagYM4_32370	ENOG4108UW5	maltose o-acetyltransferase
VagYM4_32440	ENOG4105JQN	Transcriptional regulator
VagYM4_32450	ENOG4105PAD	Hydrolase
VagYM4_32480	ENOG4108UUE	Transcriptional regulator
VagYM4_32490	ENOG4108UHE	carbonic anhydrase
VagYM4_32500	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
VagYM4_32510	ENOG4105KUU	lipolytic protein G-D-S-L family
VagYM4_32570	ENOG4105ETE	Transcriptional regulator (LacI family
VagYM4_32580	ENOG4108KAZ	Involved in phosphonate degradation (By similarity)
VagYM4_32590	ENOG4108JPW	Aminotransferase
VagYM4_32600	ENOG4107STF	Involved in phosphonate degradation (By similarity)
VagYM4_32630	ENOG4107RCV	ABC transporter, permease
VagYM4_32670	ENOG4108MJ5	VirK protein
VagYM4_32690	ENOG4105CJP	fad dependent oxidoreductase
VagYM4_32720	ENOG4105ETT	transcriptional Regulator, LysR family
VagYM4_32760	ENOG4105DUX	Transporter
VagYM4_32770	ENOG4105EJQ	L-serine dehydratase
VagYM4_32810	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
VagYM4_32820	ENOG4105E4C	Lytic transglycosylase catalytic
VagYM4_32860	ENOG4105Q75	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
VagYM4_32870	ENOG4108ZC9	flagellar basal-body rod protein flgc
VagYM4_32880	ENOG4105W00	Flagellar hook capping protein
VagYM4_32890	ENOG4105BZE	flagellar hook protein, FlgE
VagYM4_32900	ENOG4108KPB	Flagellar basal-body rod protein FlgF
VagYM4_32910	ENOG4105CGA	flagellar basal-body rod protein FlgG
VagYM4_32920	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
VagYM4_32930	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
VagYM4_32940	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
VagYM4_32950	ENOG4105E1Q	flagellar hook-associated protein
VagYM4_32960	ENOG4105DTJ	flagellar hook-associated protein
VagYM4_33000	ENOG4106UJV	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity)
VagYM4_33030	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
VagYM4_33040	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
VagYM4_33050	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
VagYM4_33080	ENOG4105N14	lysine exporter protein LysE YggA
VagYM4_33120	ENOG4107Z3H	Transcriptional regulator, TetR family
VagYM4_33130	ENOG4108K3Z	AraC family transcriptional regulator
VagYM4_33140	ENOG4105CPD	ethanolamine ammonia-lyase
VagYM4_33150	ENOG4107FQ9	ethanolamine ammonia-lyase
VagYM4_33160	ENOG4105CUB	amino acid
VagYM4_33170	ENOG4105EA8	2-Nitropropane dioxygenase
VagYM4_33180	ENOG4105CWX	Alpha-1,2-mannosidase
VagYM4_33190	ENOG4105CWX	Alpha-1,2-mannosidase
VagYM4_33210	ENOG4105CWX	Alpha-1,2-mannosidase
VagYM4_33220	ENOG4105CWX	Alpha-1,2-mannosidase
VagYM4_33230	ENOG4105DM4	PTS System
VagYM4_33250	ENOG4105E0X	reductase
VagYM4_33260	ENOG4105KHA	Glyoxalase Bleomycin resistance protein (Dioxygenase
VagYM4_33270	ENOG4105N2W	Transcriptional regulator
VagYM4_33290	ENOG4108RWI	nicotinamidase
VagYM4_33310	ENOG4107RH7	Nicotinate phosphoribosyltransferase
VagYM4_33360	ENOG4105ETT	transcriptional Regulator, LysR family
VagYM4_33390	ENOG4105RW8	MltA-interacting MipA family protein
VagYM4_33400	ENOG4107EII	Lipoprotein involved with copper homeostasis and adhesion
VagYM4_33410	ENOG4108IJ7	Glycine betaine
VagYM4_33420	ENOG4108HQS	Glycine betaine
VagYM4_33430	ENOG4105VYW	UPF0251 protein
VagYM4_33480	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
VagYM4_33490	ENOG4107S8C	mandelate racemase muconate lactonizing
VagYM4_33510	ENOG4105RQF	LysR family Transcriptional regulator
VagYM4_33530	ENOG4108Z4X	TRANSCRIPTIONal
VagYM4_33580	ENOG4107RZC	phospholipase d
VagYM4_33650	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
VagYM4_33770	ENOG4107V40	secretion protein, HlyD family
VagYM4_33800	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
VagYM4_33810	ENOG4105WH1	Two component transcriptional regulator luxr family
VagYM4_33840	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
VagYM4_33850	ENOG4105HDK	L-asparaginase
VagYM4_33860	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
VagYM4_33890	ENOG4105N14	lysine exporter protein LysE YggA
VagYM4_33900	ENOG4105IUQ	nucleoprotein polynucleotide-associated enzyme
VagYM4_33940	ENOG4105C8Y	Acetylornithine aminotransferase
VagYM4_33950	ENOG4105C26	Dehydrogenase
VagYM4_33960	ENOG4108RYR	transcriptional regulator AsnC family
VagYM4_33970	ENOG4108KJ1	Trap dicarboxylate transporter, dctp subunit
VagYM4_33980	ENOG4108KJ1	Trap dicarboxylate transporter, dctp subunit
VagYM4_33990	ENOG4105E5N	succinylglutamate desuccinylase aspartoacylase
VagYM4_34000	ENOG4105ENR	peptidase, M24
VagYM4_34010	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
VagYM4_34020	ENOG4108K1J	Transporter DctQ
VagYM4_34030	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
VagYM4_34040	ENOG4108NKV	transcriptional regulator
VagYM4_34050	ENOG4105CHR	reductase
VagYM4_34070	ENOG4105CPQ	Dehydrogenase
VagYM4_34080	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
VagYM4_34110	ENOG4107RSM	transcriptional regulator
VagYM4_34130	ENOG4105C1J	atp-dependent rna helicase
VagYM4_34170	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
VagYM4_34180	ENOG410874W	AraC family transcriptional regulator
VagYM4_34230	ENOG4108P3C	
VagYM4_34260	ENOG4105CHR	reductase
VagYM4_34320	ENOG4105C5Y	PTS System
VagYM4_34330	ENOG4105D7K	pfkb domain protein
VagYM4_34340	ENOG4108HKT	sucrose-6-phosphate hydrolase
VagYM4_34350	ENOG4105CYM	Glutathione S-transferase
VagYM4_34370	ENOG4105DZ1	carboxypeptidase
VagYM4_34400	ENOG4105EHV	domain protein
VagYM4_34410	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
VagYM4_34420	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
VagYM4_34450	ENOG4105VEQ	Cold shock protein
VagYM4_34460	ENOG4105EUB	pirin domain protein
VagYM4_34470	ENOG4108NRW	Phospholipase, patatin family
VagYM4_34510	ENOG4105EP9	oxidoreductase
VagYM4_34520	ENOG4105DIJ	Phosphoethanolamine transferase
VagYM4_34530	ENOG41080IJ	Diacylglycerol kinase
VagYM4_34550	ENOG4105E0F	Histidine kinase
VagYM4_34560	ENOG4107EXC	regulatoR
VagYM4_34590	ENOG4108Z33	Thiol disulfide Interchange Protein
VagYM4_34630	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
VagYM4_34650	ENOG4108J8Q	Catalyzes the facilitated diffusion of 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) into the cell (By similarity)
VagYM4_34670	ENOG4105EST	Metal Dependent Phosphohydrolase
VagYM4_34680	ENOG4105DZC	cytosine deaminase
VagYM4_34690	ENOG4105DQW	permease for cytosine purines, uracil, thiamine, allantoin
VagYM4_34700	ENOG4105CJW	magnesium transporter
VagYM4_34710	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
VagYM4_34720	ENOG4105EFX	secretion protein, HlyD family
VagYM4_34770	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
VagYM4_34780	ENOG4105E0F	Histidine kinase
VagYM4_34810	ENOG4105DVH	amino acid
VagYM4_34830	ENOG4105DUM	transcriptional regulator, lysR family
VagYM4_34880	ENOG4105BZU	Histidine kinase
VagYM4_34900	ENOG41090HJ	UPF0265 protein
VagYM4_34920	ENOG4108YXG	UPF0502 protein
VagYM4_34930	ENOG41082IR	Excinuclease ABC C subunit domain protein
VagYM4_34940	ENOG4108QGH	periplasmic
VagYM4_34950	ENOG4105BZU	Histidine kinase
VagYM4_34970	ENOG4105J12	Multidrug resistance protein mdtN
VagYM4_35010	ENOG4105EW9	transcriptional regulator AsnC family
VagYM4_35060	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
VagYM4_35070	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
VagYM4_35110	ENOG4105CHU	acetyl-coa acetyltransferase
VagYM4_35130	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
VagYM4_35150	ENOG4105CUW	cytochrome C-TYPE protein
VagYM4_35170	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
VagYM4_35200	ENOG4105BZU	Histidine kinase
VagYM4_35210	ENOG4105WH1	Two component transcriptional regulator luxr family
VagYM4_35240	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
VagYM4_35250	ENOG4107YWA	deoxycytidylate deaminase
VagYM4_35280	ENOG4105C8Q	Methyl-accepting chemotaxis
VagYM4_35290	ENOG4108YZN	class I peptide chain release factor
VagYM4_35300	ENOG4107VXZ	Hydrolase
VagYM4_35310	ENOG4105UYK	outer membrane protein a
VagYM4_35320	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
VagYM4_35330	ENOG4105DXI	Major Facilitator superfamily
VagYM4_35340	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
VagYM4_35350	ENOG4105CV1	Transketolase (EC 2.2.1.1)
VagYM4_35360	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
VagYM4_35390	ENOG4105BZU	Histidine kinase
VagYM4_35400	ENOG4105KHC	sulfurtransferase
VagYM4_35440	ENOG4105D06	uba thif-type nad fad binding protein
VagYM4_35450	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
VagYM4_35460	ENOG4105EUJ	GTP cyclohydrolase i
VagYM4_35470	ENOG4105C5A	transporter
VagYM4_35490	ENOG4105CMQ	Chloride channel
VagYM4_35520	ENOG4107RGM	aldo keto reductase
VagYM4_35530	ENOG4108UNF	response regulator
VagYM4_35550	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
VagYM4_35560	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
VagYM4_35570	ENOG4105DQU	oxidoreductase, subunit beta
VagYM4_35580	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
VagYM4_35600	ENOG4105DR5	peptidase
VagYM4_35660	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
VagYM4_35670	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
VagYM4_35680	ENOG4108WC9	type VI secretion system effector, hcp1 family
VagYM4_35690	ENOG4105CS6	Rhs element vgr protein
VagYM4_35740	ENOG4105D9P	serine threonine protein kinase
VagYM4_35810	ENOG4105EW9	transcriptional regulator AsnC family
VagYM4_35940	ENOG4105ENX	hydrolase
VagYM4_35950	ENOG4105C2C	drug resistance transporter, Bcr CflA
VagYM4_35970	ENOG4105CC0	LysR family Transcriptional regulator
VagYM4_35980	ENOG4105EMU	Dehydrogenase
VagYM4_35990	ENOG4105Q9Y	Universal stress protein
VagYM4_36010	ENOG4105D65	subunit l
VagYM4_36020	ENOG4105MKQ	Monovalent cation H antiporter subunit C
VagYM4_36030	ENOG4108JPZ	Monovalent cation H antiporter subunit D
VagYM4_36040	ENOG4105SC1	monovalent cation H antiporter subunit E
VagYM4_36050	ENOG41080TA	Multiple resistance and ph regulation protein f
VagYM4_36060	ENOG4105KJM	monovalent cation h antiporter subunit g
VagYM4_36070	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
VagYM4_36080	ENOG4105C10	Electron transfer flavoprotein
VagYM4_36090	ENOG4105BZJ	Electron transfer flavoprotein
VagYM4_36100	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
VagYM4_36110	ENOG4105EKQ	RNA-directed DNA polymerase
VagYM4_36120	ENOG4105C0Z	ABC transporter
VagYM4_36170	ENOG4108IV0	ABC, transporter
VagYM4_36180	ENOG4105DZS	Phenylacetate-CoA ligase
VagYM4_36200	ENOG4105C94	Transporter
VagYM4_36210	ENOG4105CHR	reductase
VagYM4_36220	ENOG4105C7K	acetolactate synthase
VagYM4_36230	ENOG4107FQX	Alpha-acetolactate decarboxylase
VagYM4_36290	ENOG4108S58	Phenazine biosynthesis protein PhzF
VagYM4_36310	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
VagYM4_36320	ENOG4105C4M	(Ubiquinol oxidase) subunit I
VagYM4_36330	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
VagYM4_36370	ENOG4105BZU	Histidine kinase
VagYM4_36380	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
VagYM4_36400	ENOG4108IPT	Naphthoate synthase
VagYM4_36410	ENOG4107QX3	carboxylase
VagYM4_36420	ENOG4105C1G	acyl-Coa dehydrogenase
VagYM4_36440	ENOG4105CHU	acetyl-coa acetyltransferase
VagYM4_36450	ENOG4105C26	Dehydrogenase
VagYM4_36460	ENOG4105C1G	acyl-Coa dehydrogenase
VagYM4_36470	ENOG4105E39	Enoyl-CoA hydratase
VagYM4_36490	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
VagYM4_36520	ENOG4108MHR	Repressor involved in choline regulation of the bet genes (By similarity)
VagYM4_36530	ENOG4105C26	Dehydrogenase
VagYM4_36540	ENOG4105CZ6	Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine (By similarity)
VagYM4_36560	ENOG4108HQS	Glycine betaine
VagYM4_36570	ENOG4108IJ7	Glycine betaine
VagYM4_36580	ENOG4108RCM	Nitroreductase
VagYM4_36600	ENOG4107QX8	SPFH domain, Band 7 family protein
VagYM4_36630	ENOG4105BZU	Histidine kinase
VagYM4_36650	ENOG4105CA0	peroxidase
VagYM4_36660	ENOG4105BZU	Histidine kinase
VagYM4_36680	ENOG4105D82	Glutamate dehydrogenase
VagYM4_36770	ENOG4108K0B	C-di-gmp phosphodiesterase
VagYM4_36780	ENOG4105MRB	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity)
VagYM4_36790	ENOG4105C2J	ABC transporter
VagYM4_36800	ENOG4105CNN	ABC, transporter
VagYM4_36810	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
VagYM4_36820	ENOG4108RVA	ribokinase
VagYM4_36830	ENOG4105ETE	Transcriptional regulator (LacI family
VagYM4_36850	ENOG4106Z1T	Nicotinamide Mononucleotide Transporter
VagYM4_36860	ENOG4108I5U	Uridine phosphorylase
VagYM4_36890	ENOG4105DHS	permease protein
VagYM4_36900	ENOG4105CM4	permease protein
VagYM4_36910	ENOG4108IPW	abc transporter atp-binding protein
VagYM4_36920	ENOG4108Z6Z	Transcriptional regulator
VagYM4_36930	ENOG4108W3Q	Transcriptional regulator
VagYM4_37000	ENOG4105EM2	membrane
VagYM4_37010	ENOG41088T4	Helicase IV
VagYM4_37020	ENOG4108Z5K	methylglyoxal synthase
VagYM4_37030	ENOG4108SV3	Tmao reductase system periplasmic protein tort
VagYM4_37040	ENOG4105BZU	Histidine kinase
VagYM4_37080	ENOG4105ENH	Sulfatase
VagYM4_37100	ENOG41061MV	Arylsulfatase
VagYM4_37110	ENOG4105C4X	radical SAM domain protein
VagYM4_37120	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
VagYM4_37180	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
VagYM4_37190	ENOG41064T2	transcriptional regulator, lysR family
VagYM4_37200	ENOG4107TE5	Lipid kinase
VagYM4_37210	ENOG4108YDI	single-species biofilm formation on inanimate substrate
VagYM4_37230	ENOG4105F2V	VRR-NUC domain-containing protein
VagYM4_37270	ENOG4105D0M	Protease HtpX homolog
VagYM4_37280	ENOG4108V0P	LemA family
VagYM4_37290	ENOG4105CEE	C4-dicarboxylate transporter
VagYM4_37330	ENOG4108MGY	Histidine kinase
VagYM4_37340	ENOG4107KBT	8-Amino-7-oxononanoate synthase
VagYM4_37350	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
VagYM4_37360	ENOG4105BZU	Histidine kinase
VagYM4_37370	ENOG4105BZU	Histidine kinase
VagYM4_37390	ENOG4108WQH	regulatoR
VagYM4_37400	ENOG4107R88	Chemotaxis protein (CheV)
VagYM4_37430	ENOG4105FR1	rard protein
VagYM4_37480	ENOG4105KPY	Small multidrug resistance protein
VagYM4_37490	ENOG4108I0N	Transporter, RarD family, DMT superfamily protein
VagYM4_37520	ENOG4107RGH	Aldehyde dehydrogenase
VagYM4_37530	ENOG4107QPK	)-transporter
VagYM4_37540	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
VagYM4_37550	ENOG4106YYS	transcriptional regulatory protein
VagYM4_37580	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
VagYM4_37610	ENOG4105EXC	Acyl-transferase
VagYM4_37630	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
VagYM4_37640	ENOG4108UYE	Lactoylglutathione lyase
VagYM4_37680	ENOG4105CJW	magnesium transporter
VagYM4_37720	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
VagYM4_37750	ENOG4105HDD	phospholipase
VagYM4_37800	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
VagYM4_37860	ENOG4105MDH	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
VagYM4_37870	ENOG4108ZI4	Glyoxalase Bleomycin resistance protein (Dioxygenase
VagYM4_37920	ENOG4107TXD	phosphoglycerate transport system transcriptional regulatory protein pgta
VagYM4_37940	ENOG4108I6A	alcohol dehydrogenase
VagYM4_37950	ENOG4105CF7	AraC family transcriptional regulator
VagYM4_37970	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
VagYM4_37980	ENOG4105CKU	formyltetrahydrofolate synthetase
VagYM4_37990	ENOG4107RE1	Inosine-guanosine kinase
VagYM4_38030	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
VagYM4_38070	ENOG4105C1J	atp-dependent rna helicase
VagYM4_38080	ENOG4108M8H	domain protein
VagYM4_38110	ENOG4105DS1	cytochrome b561
VagYM4_38120	ENOG4108YYC	ycei family
VagYM4_38130	ENOG4105TMB	Formate nitrite transporter
VagYM4_38140	ENOG4105DUM	transcriptional regulator, lysR family
VagYM4_38150	ENOG4108UQ5	membrane protein YcdZ
VagYM4_38160	ENOG4105CPB	ATP-dependent endonuclease of the OLD family
VagYM4_38170	ENOG4105CGH	5'-nucleotidase
VagYM4_38190	ENOG4105DU1	integral membrane protein, terc
VagYM4_38230	ENOG4108M0H	Extracellular lipase
VagYM4_38240	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
VagYM4_38270	ENOG4105KA0	thioesterase Superfamily protein
VagYM4_38290	ENOG4105KNR	Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity)
VagYM4_38370	ENOG4105RKW	reductase (By
VagYM4_38390	ENOG4108I0Y	(ABC) transporter
VagYM4_38400	ENOG4105CV6	ABC transporter, permease
VagYM4_38430	ENOG4105P4J	Allophanate hydrolase, subunit 1
VagYM4_38440	ENOG4105E7W	lamb ycsf family protein
VagYM4_38450	ENOG4105BZU	Histidine kinase
VagYM4_38460	ENOG4105CMR	udp-glucose 4-epimerase
VagYM4_38480	ENOG4105CWB	LysR family transcriptional Regulator
VagYM4_38490	ENOG4105CD5	CoA-binding domain protein
VagYM4_38510	ENOG4105CPF	Cell wall formation (By similarity)
VagYM4_38530	ENOG4108ZJT	translation initiation factor, Sui1
VagYM4_38550	ENOG4105MQ5	zona occludens toxin
VagYM4_38650	ENOG4105MQ5	zona occludens toxin
VagYM4_38770	ENOG4105EJC	lysr family transcriptional regulator
VagYM4_38790	ENOG4108M6U	Universal stress protein A
VagYM4_38850	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
VagYM4_38860	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
VagYM4_38930	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
VagYM4_38940	ENOG4105E0C	molybdate abc transporter
VagYM4_38950	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
VagYM4_38960	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
VagYM4_38990	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
VagYM4_39000	ENOG4105CGF	Aromatic amino acid aminotransferase
VagYM4_39010	ENOG4108K01	transcriptional regulator
VagYM4_39020	ENOG4105UQX	Mate efflux family protein
VagYM4_39030	ENOG4108RDD	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity)
VagYM4_39040	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
VagYM4_39070	ENOG4105BZS	acriflavin resistance protein
VagYM4_39140	ENOG4107TIF	Phenazine biosynthesis protein, PhzF family
VagYM4_39160	ENOG4107QKC	Oxidoreductase alpha (molybdopterin) subunit
VagYM4_39170	ENOG4105C5Q	Transcriptional regulator
VagYM4_39180	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
VagYM4_39190	ENOG4105CXY	transporter
VagYM4_39200	ENOG4108KX4	response regulator
VagYM4_39210	ENOG4105BZU	Histidine kinase
VagYM4_39220	ENOG4105CXY	transporter
VagYM4_39230	ENOG4105EIP	mannose-6-phosphate isomerase
VagYM4_39270	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
VagYM4_39280	ENOG4105K63	Thioredoxin
VagYM4_39300	ENOG4105VXR	cytoplasmic protein
VagYM4_39350	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
VagYM4_39380	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
VagYM4_39390	ENOG4105TMB	Formate nitrite transporter
VagYM4_39400	ENOG4105WZK	nitrite reductase NADPH small subunit
VagYM4_39410	ENOG4107QZF	nitrite reductase NADPH large subunit
VagYM4_39420	ENOG4105NXH	GreA GreB family elongation factor
VagYM4_39430	ENOG4105BZU	Histidine kinase
VagYM4_39520	ENOG4108NVR	Methyl-accepting chemotaxis
VagYM4_39530	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
VagYM4_39600	ENOG4105CXG	d-lactate dehydrogenase
VagYM4_39610	ENOG4105CC0	LysR family Transcriptional regulator
VagYM4_39620	ENOG4105EV2	VWA domain protein interacting with AAA ATPase
VagYM4_39630	ENOG4107R4Q	Functions as an ATPase. May play a role in metal insertion (metal-chelatase) or as a chaperone (By similarity)
VagYM4_39650	ENOG4105C5W	Aldolase
VagYM4_39660	ENOG4106RE7	Cytochrome
VagYM4_39670	ENOG4105CSX	c4-dicarboxylate anaerobic carrier
VagYM4_39690	ENOG4105QNF	Outer membrane lipoprotein
VagYM4_39710	ENOG4105EYH	Exonuclease
VagYM4_39720	ENOG4107RFY	SbcCD D subunit
VagYM4_39770	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
VagYM4_39860	ENOG4108ZF3	Phosphatase
VagYM4_39890	ENOG4106VK6	Flagellar motor protein
VagYM4_39930	ENOG4105D9P	serine threonine protein kinase
VagYM4_39970	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
VagYM4_39990	ENOG4108TGY	Glutathione S-transferase
VagYM4_40000	ENOG4108IG5	Transcriptional regulator
VagYM4_40030	ENOG4107QZF	nitrite reductase NADPH large subunit
VagYM4_40040	ENOG4105D7T	ABC transporter
VagYM4_40050	ENOG4105DG7	nitrate ABC transporter
VagYM4_40130	ENOG4105C44	Serine transporter
VagYM4_40150	ENOG4105BZU	Histidine kinase
VagYM4_40250	ENOG4106E5D	Protein of unknown function (DUF461)
VagYM4_40260	ENOG4105R8A	Heat shock protein
VagYM4_40290	ENOG4107RUY	(E1 component), alpha subunit
VagYM4_40300	ENOG4105CPP	Dehydrogenase, E1 component
VagYM4_40310	ENOG4107QSN	dihydrolipoamide acetyltransferase
VagYM4_40320	ENOG4105C10	Electron transfer flavoprotein
VagYM4_40330	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
VagYM4_40390	ENOG4105DMR	ABC, transporter
VagYM4_40400	ENOG4105GBT	ABC transporter
VagYM4_40410	ENOG4106PMH	Extracellular solute-binding protein family 3
VagYM4_40420	ENOG4105E5Z	arginine transporter ATP-binding subunit
VagYM4_40500	ENOG4105C26	Dehydrogenase
VagYM4_40540	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
VagYM4_40560	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
VagYM4_40580	ENOG4105CCU	oxidase (Subunit III)
VagYM4_40590	ENOG4105BZ9	Cytochrome C oxidase, subunit I
VagYM4_40600	ENOG4105E2S	oxidase) subunit II
VagYM4_40610	ENOG4105CHR	reductase
VagYM4_40620	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
VagYM4_40630	ENOG4105E39	Enoyl-CoA hydratase
VagYM4_40640	ENOG4105E39	Enoyl-CoA hydratase
VagYM4_40660	ENOG4105C26	Dehydrogenase
VagYM4_40670	ENOG4105CHU	acetyl-coa acetyltransferase
VagYM4_40690	ENOG4105C1G	acyl-Coa dehydrogenase
VagYM4_40700	ENOG4107QX3	carboxylase
VagYM4_40710	ENOG4105E39	Enoyl-CoA hydratase
VagYM4_40720	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
VagYM4_40750	ENOG4105CQB	FAD linked oxidase domain protein
VagYM4_40770	ENOG4107U2T	alpha beta
VagYM4_40780	ENOG4105ECQ	AraC Family Transcriptional Regulator
VagYM4_40810	ENOG4107SI7	Substrate-binding region of abc-type glycine betaine transport system
VagYM4_40820	ENOG4108U0I	binding-protein-dependent transport systems inner membrane Component
VagYM4_40830	ENOG4108IJ8	ABC transporter
VagYM4_40840	ENOG4105E90	ABC transporter
VagYM4_40850	ENOG4107SDU	Methyl-accepting chemotaxis
VagYM4_40860	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
VagYM4_40870	ENOG4105BZU	Histidine kinase
VagYM4_40880	ENOG4105C1J	atp-dependent rna helicase
VagYM4_40890	ENOG4108ENQ	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction (By similarity)
VagYM4_40940	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
VagYM4_40950	ENOG4105DKW	ABC transporter
VagYM4_40960	ENOG4105CXC	rtn protein
VagYM4_41010	ENOG4105C1J	atp-dependent rna helicase
VagYM4_41020	ENOG4105CKI	cobalamin synthesis protein
VagYM4_41040	ENOG4108KN7	Removes 5-oxoproline from various penultimate amino acid residues except L-proline (By similarity)
VagYM4_41060	ENOG4105VEQ	Cold shock protein
VagYM4_41070	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
VagYM4_41080	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
VagYM4_41100	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
VagYM4_41110	ENOG4105C1J	atp-dependent rna helicase
VagYM4_41130	ENOG4105HF0	Membrane
VagYM4_41170	ENOG4105CXN	decarboxylase
VagYM4_41180	ENOG4105CHJ	isochorismatase hydrolase
VagYM4_41200	ENOG4107QR7	peptidase S8 and S53, subtilisin, kexin, sedolisin
VagYM4_41230	ENOG4105VRT	cytoplasmic protein
VagYM4_41270	ENOG41090A4	Pterin carbinolamine dehydratase
VagYM4_41280	ENOG4105MIR	Phenylalanine 4-monooxygenase
VagYM4_41290	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
VagYM4_41300	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
VagYM4_41350	ENOG4108556	Isoprenoid biosynthesis protein with amidotransferase-like domain
VagYM4_41360	ENOG4105C0A	alcohol dehydrogenase
VagYM4_41390	ENOG4108RMU	ferritin dps family protein
VagYM4_41400	ENOG4105C8Q	Methyl-accepting chemotaxis
VagYM4_41420	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
VagYM4_41460	ENOG4105BZU	Histidine kinase
VagYM4_41480	ENOG4105VEQ	Cold shock protein
VagYM4_41520	ENOG4108ZG0	Ompa motb domain protein
VagYM4_41540	ENOG4108V1T	peptidylprolyl cis-trans isomerase
VagYM4_41550	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
VagYM4_41560	ENOG4107TQK	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group (By similarity)
VagYM4_41600	ENOG4105FT1	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I (By similarity)
VagYM4_41610	ENOG4105BZ9	Cytochrome C oxidase, subunit I
VagYM4_41650	ENOG4105CCF	Lysine exporter protein (Lyse ygga)
VagYM4_41660	ENOG4105SUT	Transcriptional Regulator AraC Family
VagYM4_41690	ENOG4105FBJ	fumarylacetoacetate (faa) hydrolase
VagYM4_41730	ENOG4108SXK	Transporter Drug Metabolite Exporter family
VagYM4_41740	ENOG4105VW4	glutaredoxin 3
VagYM4_41770	ENOG4105E5M	Multidrug resistance protein D
VagYM4_41780	ENOG4105CR8	Transcriptional regulator
VagYM4_41800	ENOG4105DR5	peptidase
VagYM4_41850	ENOG4105DWD	nucleoside recognition domain protein
VagYM4_41860	ENOG4105C8Q	Methyl-accepting chemotaxis
VagYM4_41880	ENOG4105E0U	tyrosine-specific transport protein
VagYM4_41920	ENOG4107Z1W	Fructose transport system kinase
VagYM4_41940	ENOG4105DXH	Alcohol dehydrogenase zinc-binding domain protein
VagYM4_41950	ENOG4105CTS	PTS system mannitol-specific
VagYM4_41960	ENOG4108X7Y	Mannitol-specific cryptic phosphotransferase enzyme iia
VagYM4_41990	ENOG4105D6J	arsenicaL-resistance protein
VagYM4_42010	ENOG4108V1U	phospholipid-binding protein
VagYM4_42020	ENOG4105JAB	phenazine biosynthesis protein, phzf family
VagYM4_42030	ENOG4105HHQ	6-phosphogluconolactonase (EC 3.1.1.31)
VagYM4_42050	ENOG4105CJ1	ABC, transporter
VagYM4_42060	ENOG4107QWP	ABC-2 type transporter
VagYM4_42090	ENOG4108IEG	Formate dehydrogenase Alpha subunit
VagYM4_42130	ENOG4108IJF	Heavy metal efflux pump, CzcA
VagYM4_42190	ENOG4108HK0	-acetyltransferase
VagYM4_42210	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
VagYM4_42230	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
VagYM4_42270	ENOG4105C5H	ABC transporter
VagYM4_42280	ENOG4108M6U	Universal stress protein A
VagYM4_42290	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
VagYM4_42300	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
VagYM4_42340	ENOG4105VUF	Transcriptional regulator
VagYM4_42350	ENOG4108Z8I	decarboxylase
VagYM4_42370	ENOG4105KXC	Collagenase
VagYM4_42400	ENOG4105CR8	Transcriptional regulator
VagYM4_42410	ENOG4105C8Q	Methyl-accepting chemotaxis
VagYM4_42430	ENOG41061MD	high-affinity nickel-transporter
VagYM4_42440	ENOG41090EM	Repressor of rcnA expression. Acts by binding specifically to the rcnA promoter in the absence of nickel and cobalt. In the presence of one of these metals, it has a weaker affinity for rcnA promoter
VagYM4_42470	ENOG4105KQ5	peptidylprolyl cis-trans isomerase
VagYM4_42500	ENOG4105PYN	Pyridoxamine 5-phosphate oxidase-related
VagYM4_42510	ENOG41090JE	Utilization Protein
VagYM4_42520	ENOG4105D4P	Coproporphyrinogen iii oxidase
VagYM4_42530	ENOG4105WQ5	TonB family
VagYM4_42540	ENOG41090AP	transport protein
VagYM4_42550	ENOG4106GFD	transport protein
VagYM4_42570	ENOG4105EHG	Permease protein
VagYM4_42580	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
VagYM4_42670	ENOG4107X4V	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
VagYM4_42680	ENOG4107RA1	nh(3)-dependent nad( ) synthetase
VagYM4_42690	ENOG4105QVC	MOSC domain-containing protein
VagYM4_42690	ENOG4105QVC	MOSC domain-containing protein
VagYM4_42710	ENOG4105EKE	dihydroorotase
VagYM4_42720	ENOG4105CKW	Inner membrane protein yedI
VagYM4_42780	ENOG4105EG2	ABC transporter, permease
VagYM4_42790	ENOG4105D56	permease protein
VagYM4_42800	ENOG4107FKK	extracellular solute-binding protein family 1
VagYM4_42810	ENOG4108IJ9	(ABC) transporter
VagYM4_42820	ENOG4105D3Q	Sugar transferase
VagYM4_42850	ENOG4105D75	Capsular exopolysaccharide family
VagYM4_42930	ENOG4105V0I	UPF0267 protein
VagYM4_42940	ENOG4108WUH	Transcriptional regulator, TetR family
VagYM4_42950	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
VagYM4_42960	ENOG4108RXX	maleylacetoacetate isomerase
VagYM4_42970	ENOG4105CH6	catalase
VagYM4_42980	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
VagYM4_42990	ENOG4105DM4	PTS System
VagYM4_43000	ENOG4108YRF	PTS System
VagYM4_43020	ENOG4106R3P	AraC family transcriptional regulator
VagYM4_43030	ENOG4105DM4	PTS System
VagYM4_43040	ENOG4105EIP	mannose-6-phosphate isomerase
VagYM4_43060	ENOG4105MN5	HAD-superfamily hydrolase subfamily IA variant 3
VagYM4_43080	ENOG4105CK1	PTS System
VagYM4_43100	ENOG4105CJP	fad dependent oxidoreductase
VagYM4_43110	ENOG4107QZF	nitrite reductase NADPH large subunit
VagYM4_43130	ENOG4105DVW	rieske (2Fe-2S)
VagYM4_43150	ENOG4105ETT	transcriptional Regulator, LysR family
VagYM4_43160	ENOG4105CZN	Potassium uptake protein
VagYM4_43200	ENOG4105BZ1	(ABC) transporter
VagYM4_43210	ENOG4105E0K	tonB-dependent siderophore receptor
VagYM4_43220	ENOG4105E0A	ABC, transporter
VagYM4_43230	ENOG4108HUF	Transporter
VagYM4_43240	ENOG4105S6R	Iron-hydroxamate transporter permease subunit
VagYM4_43270	ENOG4108JJ6	Type I secretion system ATPase
VagYM4_43290	ENOG41086KC	Transcriptional regulator
VagYM4_43300	ENOG41086KC	Transcriptional regulator
VagYM4_43320	ENOG41069D7	Methyl-accepting chemotaxis
VagYM4_43330	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
VagYM4_43360	ENOG4107QVM	von Willebrand factor, type A
VagYM4_43400	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
VagYM4_43410	ENOG4105E2Z	phosphate ABC transporter (Permease
VagYM4_43420	ENOG4105C8U	phosphate abc transporter
VagYM4_43480	ENOG4105D05	Receptor
VagYM4_43490	ENOG4105CUG	Oligopeptidase b
VagYM4_43500	ENOG4105C1J	atp-dependent rna helicase
VagYM4_43520	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
VagYM4_43530	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
VagYM4_43540	ENOG4108XDN	Transcriptional regulator
VagYM4_43550	ENOG4107SEY	Conserved Protein
VagYM4_43560	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
VagYM4_43590	ENOG4106TD9	Diguanylate cyclase
VagYM4_43600	ENOG4105KK7	inner membrane protein YiaW
VagYM4_43610	ENOG4105EFX	secretion protein, HlyD family
VagYM4_43620	ENOG4108V7D	UPF0397 protein
VagYM4_43630	ENOG4108JJB	ABC transporter
VagYM4_43670	ENOG4105GXZ	Ferredoxin-type protein NapH
VagYM4_43680	ENOG4108BGM	Quinol dehydrogenase periplasmic component
VagYM4_43690	ENOG4105WCN	acetyltransferase
VagYM4_43720	ENOG4105YE1	PilZ domain
VagYM4_43730	ENOG4107QE9	Inherit from COG: Membrane
VagYM4_43740	ENOG4105C8Q	Methyl-accepting chemotaxis
VagYM4_43750	ENOG4105DAN	ATP-dependent protease
VagYM4_43770	ENOG4108JQ5	ABC transporter
VagYM4_43790	ENOG410642W	LysR family Transcriptional regulator
VagYM4_43800	ENOG4105DAA	L-lactate
VagYM4_43810	ENOG4105DMF	Dehydrogenase
VagYM4_43830	ENOG4105D64	Mechanosensitive ion channel
VagYM4_43850	ENOG4105CPQ	Dehydrogenase
VagYM4_43860	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
VagYM4_43870	ENOG4105BZU	Histidine kinase
VagYM4_43880	ENOG4107R0W	ABC transporter
VagYM4_43900	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
VagYM4_43920	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
VagYM4_43960	ENOG4105EXG	Transcriptional regulator
VagYM4_43970	ENOG4108YZK	glyoxalase bleomycin resistance protein dioxygenase
VagYM4_44000	ENOG4107SSZ	Phosphatase
VagYM4_44060	ENOG4108JIR	Flagellum-specific ATP synthase
VagYM4_44080	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
VagYM4_44090	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
VagYM4_44140	ENOG4105DD5	Flagellar motor switch protein
VagYM4_44150	ENOG4105CN7	Flagellar biosynthetic protein FliP
VagYM4_44160	ENOG4105VS8	Flagellar biosynthetic protein fliq
VagYM4_44170	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
VagYM4_44180	ENOG4105D00	flagellar biosynthetic protein flhB
VagYM4_44210	ENOG4105I03	Flagellin
VagYM4_44250	ENOG410804A	Flagellar hook-associated 2 domain-containing protein
VagYM4_44260	ENOG4105MQ3	flagellar protein FliS
VagYM4_44310	ENOG4107RD7	Flagellar Motor Protein, MotA
VagYM4_44320	ENOG4105ER2	Ompa motb domain protein
VagYM4_44350	ENOG4105KWG	Pfam:DUF1696
VagYM4_44430	ENOG4105F1A	Pyruvate formate-lyase
VagYM4_44440	ENOG4107T9Z	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
VagYM4_44460	ENOG4105I4A	GCN5-related N-acetyltransferase
VagYM4_44480	ENOG4105CNH	Multidrug resistance protein MdtL
VagYM4_44490	ENOG4105G2Y	Transcriptional regulator
VagYM4_44560	ENOG4105IPI	Membrane
VagYM4_44570	ENOG41068P6	UPF0319 protein
VagYM4_44580	ENOG4105DP0	ferredoxin-NADP reductase
VagYM4_44600	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
VagYM4_44610	ENOG4105ETT	transcriptional Regulator, LysR family
VagYM4_44630	ENOG4108RCM	Nitroreductase
VagYM4_44640	ENOG4108ZX5	transcriptional regulator
VagYM4_44660	ENOG4105DZ1	carboxypeptidase
VagYM4_44690	ENOG4105C72	UPF0176 protein
VagYM4_44710	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
VagYM4_44730	ENOG4108M1A	Chitin-binding protein
VagYM4_44740	ENOG4108NRW	Phospholipase, patatin family
VagYM4_44750	ENOG41081FY	multiple antibiotic resistance (MarC)-related
VagYM4_44780	ENOG4105DAY	polysaccharide export protein
VagYM4_44790	ENOG4105KJF	protein tyrosine phosphatase
VagYM4_44820	ENOG4105CK2	sodium dicarboxylate symporter
VagYM4_44850	ENOG4108P2H	Inner membrane protein YjiG
VagYM4_44860	ENOG41074DU	domain protein
VagYM4_44880	ENOG4107T9C	Alpha amylase catalytic region
VagYM4_44890	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
VagYM4_44900	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
VagYM4_44910	ENOG4107RTM	4-alpha-glucanotransferase (EC 2.4.1.25)
VagYM4_44920	ENOG4107QQN	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
VagYM4_44930	ENOG41061ZR	Transcriptional regulator
VagYM4_44980	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
VagYM4_44990	ENOG4107QV7	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) (By similarity)
VagYM4_45000	ENOG4107XGF	functions in a salvage pathway. Uses pyridoxamine (By similarity)
VagYM4_45020	ENOG4105D5Q	Arginine ornithine antiporter
VagYM4_45030	ENOG4105CXN	decarboxylase
VagYM4_45070	ENOG4108K8S	endonuclease I
VagYM4_45110	ENOG4108KDD	Involved in the transport of maltose and maltodextrins (By similarity)
VagYM4_45190	ENOG4105DR5	peptidase
VagYM4_45200	ENOG4107RAN	Peptidase, M16
VagYM4_45210	ENOG4105C8Q	Methyl-accepting chemotaxis
VagYM4_45220	ENOG4105E0A	ABC, transporter
VagYM4_45230	ENOG4108U1V	ABC transporter, permease
VagYM4_45240	ENOG4105DQ5	transport system permease protein
VagYM4_45250	ENOG4108HUF	Transporter
VagYM4_45260	ENOG4105GAV	receptor
VagYM4_45270	ENOG4105E0K	tonB-dependent siderophore receptor
VagYM4_45290	ENOG4105DUU	IucA IucC family protein
VagYM4_45310	ENOG4105DBM	Siderophore biosynthesis protein
VagYM4_45320	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
VagYM4_45330	ENOG4108JP0	extracellular solute-binding protein family 1
VagYM4_45340	ENOG4105DHQ	Histidine kinase
VagYM4_45360	ENOG4105CI1	PTS System
VagYM4_45420	ENOG4105CKK	Glycosyl transferase, family 2
VagYM4_45490	ENOG4108ZHJ	Organic hydroperoxide resistance protein
VagYM4_45500	ENOG4105K56	Transcriptional regulator
VagYM4_45510	ENOG4105D3R	alkyl hydroperoxide reductase
VagYM4_45520	ENOG4108JU3	Alkyl hydroperoxide reductase
VagYM4_45550	ENOG4105EXG	Transcriptional regulator
VagYM4_45560	ENOG4105ECQ	AraC Family Transcriptional Regulator
VagYM4_45570	ENOG4108AEY	RNA polymerase sigma factor
VagYM4_45610	ENOG4108RPX	mosc domain containing protein
VagYM4_45660	ENOG4105CF7	AraC family transcriptional regulator
VagYM4_45680	ENOG4105BZ1	(ABC) transporter
VagYM4_45700	ENOG4105EW9	transcriptional regulator AsnC family
VagYM4_45730	ENOG4105KNA	-acetyltransferase
VagYM4_45760	ENOG4105CK7	Sodium proline symporter
VagYM4_45770	ENOG4105CK7	Sodium proline symporter
VagYM4_45790	ENOG4105C26	Dehydrogenase
VagYM4_45820	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
VagYM4_45830	ENOG4105CQZ	Histidine kinase
VagYM4_45840	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
VagYM4_45850	ENOG4107QZV	Type I secretion membrane fusion protein
VagYM4_45880	ENOG4108JJA	ABC, transporter
VagYM4_45920	ENOG4108J59	Extracellular solute-binding protein, family 5
VagYM4_45940	ENOG4108PSC	Represses the expression of the murPQ operon involved in the uptake and degradation of N-acetylmuramic acid (MurNAc). Binds to two adjacent inverted repeats within the operator region. MurNAc 6-phosphate, the substrate of MurQ, is the specific inducer that weakens binding of MurR to the operator (By similarity)
VagYM4_45950	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
VagYM4_45960	ENOG4105C5Y	PTS System
VagYM4_45970	ENOG4105FCK	Membrane
VagYM4_46010	ENOG4105E0I	Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) (By similarity)