locus-tag	class	description
PL14_00005	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
PL14_00010	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
PL14_00015	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
PL14_00020	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
PL14_00025	ENOG4108ZNX	Heat shock protein
PL14_00030	ENOG4105JKW	Valine--pyruvate aminotransferase
PL14_00035	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
PL14_00040	ENOG4107QIB	glycyl-tRNA synthetase, alpha subunit
PL14_00055	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
PL14_00070	ENOG4105D3Z	quinone oxidoreductase, yhdh yhfp family
PL14_00075	ENOG4105C7B	Threonine dehydratase
PL14_00080	ENOG4105C01	Dihydroxy-acid dehydratase
PL14_00085	ENOG4105CM2	brancheD-chain amino acid aminotransferase
PL14_00090	ENOG4105P3Y	Acetolactate synthase 2 regulatory subunit
PL14_00120	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
PL14_00125	ENOG4108N3W	hemolysin secretion protein
PL14_00130	ENOG4108N3W	hemolysin secretion protein
PL14_00145	ENOG4105BZU	Histidine kinase
PL14_00160	ENOG4105EKQ	RNA-directed DNA polymerase
PL14_00175	ENOG4108Z33	Thiol disulfide Interchange Protein
PL14_00180	ENOG4105E27	serine threonine protein kinase
PL14_00195	ENOG4105PC1	Conserved Protein
PL14_00200	ENOG4108UT2	hemolysin iii
PL14_00210	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
PL14_00215	ENOG4105C1A	potassium transporter peripheral membrane
PL14_00220	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
PL14_00225	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
PL14_00230	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
PL14_00235	ENOG4108WZM	domain protein
PL14_00240	ENOG4105C79	DNA protecting protein DprA
PL14_00245	ENOG4108RPN	Protein smg homolog
PL14_00250	ENOG4108WI1	Dna topoisomerase
PL14_00255	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
PL14_00260	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
PL14_00265	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
PL14_00270	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
PL14_00275	ENOG4105E2X	shikimate dehydrogenase
PL14_00280	ENOG4105SG3	Protein of unknown function (DUF1488)
PL14_00285	ENOG4108Z0R	Transferase
PL14_00315	ENOG410601J	HemY protein
PL14_00320	ENOG4105ECF	c-methyltransferase
PL14_00325	ENOG41076E6	Uroporphyrinogen-III Synthase
PL14_00330	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
PL14_00335	ENOG4107T0K	Adenylate cyclase
PL14_00340	ENOG4105XQ6	frataxin-like protein
PL14_00350	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
PL14_00355	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
PL14_00365	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
PL14_00370	ENOG4105DFC	had-superfamily hydrolase, subfamily ia, variant
PL14_00375	ENOG4106IUH	DTW domain containing protein
PL14_00385	ENOG4105DQF	Hydrolase
PL14_00390	ENOG4108EUD	Lysophospholipase
PL14_00395	ENOG410829K	Lysine exporter protein (Lyse ygga)
PL14_00400	ENOG4105D58	Diguanylate phosphodiesterase
PL14_00405	ENOG4108RMU	ferritin dps family protein
PL14_00430	ENOG41076UM	multiple antibiotic resistance (MarC)-related protein
PL14_00475	ENOG4105EJQ	L-serine dehydratase
PL14_00485	ENOG4105D2S	major facilitator superfamily
PL14_00500	ENOG4105ETE	Transcriptional regulator (LacI family
PL14_00560	ENOG4106H78	methyltransferase
PL14_00565	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
PL14_00570	ENOG4105CAK	Cell division ATP-binding protein ftsE
PL14_00575	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
PL14_00580	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
PL14_00585	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
PL14_00590	ENOG4105EBW	Rhomboid-type serine protease that catalyzes intramembrane proteolysis (By similarity)
PL14_00595	ENOG4105X6C	Flagellar basal body-associated protein FliL
PL14_00600	ENOG4105VEI	Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway (By similarity)
PL14_00605	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
PL14_00610	ENOG4105E55	glycerol-3-phosphate acyltransferase
PL14_00615	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
PL14_00625	ENOG4107R73	Mate efflux family protein
PL14_00630	ENOG4105DX1	Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation (By similarity)
PL14_00640	ENOG4108Y73	Membrane
PL14_00650	ENOG4107R9T	Catalyzes the formation of 5-methyl-uridine at position 54 (m5U54) in all tRNAs (By similarity)
PL14_00655	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
PL14_00665	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
PL14_00740	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
PL14_00745	ENOG4105BZU	Histidine kinase
PL14_00750	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
PL14_00755	ENOG4105CUX	Signal transduction histidine kinase
PL14_00765	ENOG4105C5F	glutamine synthetase
PL14_00775	ENOG4107S2Z	UPF0761 membrane protein
PL14_00780	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
PL14_00785	ENOG4105SUU	thioesterase domain
PL14_00795	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
PL14_00800	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
PL14_00805	ENOG4105VEJ	Heat shock protein
PL14_00810	ENOG4108XKW	General secretion pathway protein C
PL14_00820	ENOG4107QHF	type ii secretion system protein e
PL14_00825	ENOG4105D7Q	type ii secretion system
PL14_00830	ENOG4108VAU	general secretion pathway protein G
PL14_00835	ENOG4105VWV	general secretion pathway protein h
PL14_00840	ENOG4105X5Z	General secretion pathway protein I
PL14_00845	ENOG4108WWZ	General secretion pathway protein J
PL14_00850	ENOG4108RTD	type II secretion system protein K
PL14_00855	ENOG4108BY5	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins (By similarity)
PL14_00860	ENOG4105U1E	general secretion pathway protein M
PL14_00865	ENOG4105PIC	general secretion pathway protein N
PL14_00870	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
PL14_00875	ENOG4107RK2	ADP-ribose diphosphatase NudE
PL14_00880	ENOG4107RUK	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins (By similarity)
PL14_00885	ENOG4105MJ2	Competence protein
PL14_00900	ENOG4105BZM	domain protein
PL14_00905	ENOG4108RRZ	Transcription elongation factor GreB
PL14_00915	ENOG4105RA2	Membrane
PL14_00925	ENOG4105ETT	transcriptional Regulator, LysR family
PL14_00935	ENOG4108RCM	Nitroreductase
PL14_00945	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
PL14_00950	ENOG4105E0F	Histidine kinase
PL14_00955	ENOG4105C2W	permease
PL14_00960	ENOG4105CB5	ATP-dependent DNA helicase recG
PL14_00965	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
PL14_00970	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
PL14_00975	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
PL14_00980	ENOG4105EX9	Membrane
PL14_00985	ENOG4105C9X	ppx gppa phosphatase
PL14_00990	ENOG4105C1J	atp-dependent rna helicase
PL14_00995	ENOG4105K63	Thioredoxin
PL14_01000	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
PL14_01010	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
PL14_01020	ENOG4107QK7	reductase
PL14_01060	ENOG4105JIM	Phosphatidylserine synthase
PL14_01070	ENOG4105D4A	Cell wall formation (By similarity)
PL14_01075	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
PL14_01080	ENOG4105CS9	pantothenic acid kinase
PL14_01105	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
PL14_01110	ENOG4105PM1	preprotein translocase subunit SecE
PL14_01115	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
PL14_01120	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
PL14_01125	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
PL14_01130	ENOG4108VZM	50s ribosomal protein L10
PL14_01135	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
PL14_01140	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
PL14_01145	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
PL14_01150	ENOG4108ZVW	Anti-RNA polymerase sigma 70 factor
PL14_01155	ENOG4105E09	nadh pyrophosphatase
PL14_01160	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
PL14_01165	ENOG41062JF	Transcriptional regulator
PL14_01175	ENOG41063SB	peptidase
PL14_01180	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
PL14_01190	ENOG4105C8Q	Methyl-accepting chemotaxis
PL14_01195	ENOG4107QWE	)-transporter
PL14_01200	ENOG4105DJ4	phosphatidylserine decarboxylase
PL14_01205	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
PL14_01210	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
PL14_01260	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
PL14_01265	ENOG4105K8N	protein family UPF0079, ATPase
PL14_01270	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
PL14_01275	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
PL14_01280	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
PL14_01285	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
PL14_01290	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
PL14_01295	ENOG4107QJR	hflk protein
PL14_01300	ENOG4105EPW	hflc protein
PL14_01310	ENOG41069P5	Protein slyX homolog
PL14_01320	ENOG4108V1T	peptidylprolyl cis-trans isomerase
PL14_01325	ENOG4105WWK	YheO domain protein
PL14_01330	ENOG4108ZAT	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE (By similarity)
PL14_01335	ENOG4108ZKU	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (By similarity)
PL14_01345	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
PL14_01350	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
PL14_01360	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
PL14_01365	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
PL14_01370	ENOG4108VDV	Binds single-stranded DNA at the primosome assembly site (PAS) (By similarity)
PL14_01375	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
PL14_01380	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
PL14_01390	ENOG4105CDU	Replicative dna helicase
PL14_01395	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
PL14_01400	ENOG4107QP8	phosphohexose isomerase
PL14_01410	ENOG4105MYN	Zinc uptake regulation protein
PL14_01440	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
PL14_01460	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
PL14_01465	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
PL14_01470	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
PL14_01540	ENOG4105EEQ	Na H antiporter
PL14_01545	ENOG4105C3R	Methionine synthase
PL14_01550	ENOG4105CFH	Aspartokinase
PL14_01555	ENOG4105C5R	Aminotransferase
PL14_01565	ENOG4105CJW	magnesium transporter
PL14_01580	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
PL14_01585	ENOG41086KC	Transcriptional regulator
PL14_01590	ENOG4108UUM	single-stranded DNA-binding protein
PL14_01595	ENOG41062P1	Diguanylate cyclase phosphodiesterase
PL14_01630	ENOG4107QHF	type ii secretion system protein e
PL14_01635	ENOG4105D7Q	type ii secretion system
PL14_01680	ENOG4105DFF	Rod shape-determining protein mreb
PL14_01685	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
PL14_01690	ENOG4105VQ7	Rod shape-determining protein MreD
PL14_01695	ENOG4108Z03	MAF-like protein
PL14_01700	ENOG4105C03	ribonuclease
PL14_01705	ENOG4105QD6	exported protein
PL14_01715	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
PL14_01720	ENOG4105CEU	Arginine dihydrolase
PL14_01740	ENOG41081QV	Universal stress protein
PL14_01755	ENOG410682Y	Regulates arginine biosynthesis genes (By similarity)
PL14_01760	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
PL14_01765	ENOG4105D5Q	Arginine ornithine antiporter
PL14_01770	ENOG4105EAH	synthase
PL14_01775	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
PL14_01780	ENOG4105K46	50S ribosomal protein l27
PL14_01785	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
PL14_01790	ENOG4105DWK	Membrane
PL14_01795	ENOG4107XM3	UPF0442 protein
PL14_01805	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
PL14_01810	ENOG4105NWN	ApaG protein
PL14_01815	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
PL14_01820	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
PL14_01825	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
PL14_01830	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
PL14_01835	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
PL14_01885	ENOG4106S48	Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division
PL14_01890	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
PL14_01895	ENOG4105CEN	a g-specific adenine glycosylase
PL14_01900	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
PL14_01905	ENOG4105CSV	Glutaminase
PL14_01910	ENOG4105CSA	Coproporphyrinogen iii oxidase
PL14_01915	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
PL14_01925	ENOG4105VZ9	UPF0235 protein
PL14_01930	ENOG4108VIA	integral membrane protein
PL14_01935	ENOG4105II7	pyrroline-5-carboxylate reductase
PL14_01940	ENOG4105DFA	alanine racemase domain protein
PL14_01945	ENOG4105CZX	twitching motility protein
PL14_01950	ENOG4105CZX	twitching motility protein
PL14_01960	ENOG4108UJU	UPF0301 protein
PL14_01965	ENOG4105D7Z	glutathione synthase
PL14_01970	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
PL14_01975	ENOG4105RWS	endonuclease I
PL14_01985	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
PL14_01995	ENOG4108R4R	Iron-regulated virulence regulatory protein
PL14_02000	ENOG4105D05	Receptor
PL14_02005	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
PL14_02010	ENOG4105BZA	Phosphoglycerate kinase
PL14_02015	ENOG4105D2N	Aldolase
PL14_02020	ENOG4105D64	Mechanosensitive ion channel
PL14_02025	ENOG4108RS6	transposase
PL14_02030	ENOG4108ZUB	Lysine exporter protein (Lyse ygga)
PL14_02035	ENOG4105CXD	Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity)
PL14_02045	ENOG4105BZU	Histidine kinase
PL14_02050	ENOG4105CA9	Pyruvate kinase
PL14_02055	ENOG410804X	Transcriptional regulator
PL14_02060	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
PL14_02070	ENOG4108YZN	class I peptide chain release factor
PL14_02075	ENOG4108WC9	type VI secretion system effector, hcp1 family
PL14_02080	ENOG4105CS6	Rhs element vgr protein
PL14_02115	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
PL14_02120	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
PL14_02125	ENOG4105KTH	gatB Yqey
PL14_02130	ENOG4105VCC	30S ribosomal protein S21
PL14_02135	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
PL14_02145	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
PL14_02150	ENOG4107ZVW	dihydroneopterin aldolase
PL14_02155	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
PL14_02160	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
PL14_02165	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
PL14_02170	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
PL14_02175	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
PL14_02180	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
PL14_02185	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
PL14_02190	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
PL14_02195	ENOG4108K5P	(LipO)protein
PL14_02200	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
PL14_02205	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
PL14_02210	ENOG4105C6T	cysteine synthase
PL14_02215	ENOG4108J2H	Sulfate ABC transporter periplasmic sulfate-binding protein
PL14_02220	ENOG4108I5D	sulfate abc transporter
PL14_02225	ENOG4105ECW	sulfate abc transporter
PL14_02230	ENOG4108IJ6	ABC transporter
PL14_02235	ENOG4107TH8	cina domain protein
PL14_02240	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
PL14_02245	ENOG4105Y3E	Modulates RecA activity (By similarity)
PL14_02250	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
PL14_02255	ENOG4105CFH	Aspartokinase
PL14_02260	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
PL14_02310	ENOG4107QSA	Oxaloacetate decarboxylase
PL14_02315	ENOG4105D9Q	decarboxylase (Beta subunit)
PL14_02320	ENOG4105CPQ	Dehydrogenase
PL14_02325	ENOG4105W39	Membrane
PL14_02335	ENOG4105D9M	gamma-glutamylcysteine synthetase
PL14_02340	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
PL14_02345	ENOG4108JU6	CBS domain protein
PL14_02350	ENOG4106KVJ	cytochrome C assembly protein
PL14_02355	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
PL14_02360	ENOG4105K5M	30s ribosomal protein S16
PL14_02365	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
PL14_02370	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
PL14_02375	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
PL14_02380	ENOG41067SF	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity)
PL14_02385	ENOG4105DHA	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity (By similarity)
PL14_02390	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
PL14_02395	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
PL14_02400	ENOG4105D7Q	type ii secretion system
PL14_02405	ENOG4107QHF	type ii secretion system protein e
PL14_02415	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
PL14_02425	ENOG41071R3	Low-potential electron donor to a number of redox enzymes (By similarity)
PL14_02430	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
PL14_02435	ENOG4105T95	Thiol disulfide interChange protein
PL14_02440	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
PL14_02445	ENOG41073TP	transcriptional regulator
PL14_02450	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
PL14_02455	ENOG4107QSN	dihydrolipoamide acetyltransferase
PL14_02460	ENOG4107QN2	dihydrolipoyl dehydrogenase
PL14_02465	ENOG410630P	Transcriptional regulator
PL14_02470	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
PL14_02475	ENOG41077A9	carbonic anhydrase
PL14_02480	ENOG4105CHH	sulfate transporter
PL14_02485	ENOG4105DA5	(ABC) transporter
PL14_02490	ENOG4105E3A	(ABC) transporter
PL14_02505	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
PL14_02510	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
PL14_02515	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
PL14_02520	ENOG4105DJ0	Poly(A) Polymerase
PL14_02525	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
PL14_02530	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
PL14_02535	ENOG4105PW4	Sugar fermentation stimulation protein homolog
PL14_02540	ENOG4105CQ7	ATP-dependent helicase
PL14_02545	ENOG4105BZ4	penicillin-binding protein
PL14_02550	ENOG4105D78	K07001 NTE family protein
PL14_02555	ENOG4107QIJ	Aconitate hydratase 2
PL14_02560	ENOG4105BZW	Glycerate kinase
PL14_02565	ENOG4107QQ0	gntp family
PL14_02570	ENOG4108IXP	Carbohydrate diacid transcriptional activator CdaR
PL14_02575	ENOG4105XTV	UPF0231 protein
PL14_02580	ENOG4108YZA	Nitrogen regulatory protein pii
PL14_02600	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
PL14_02605	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
PL14_02615	ENOG4105E2D	ec 3.2.1.52
PL14_02620	ENOG4105RD7	BadF BadG BcrA BcrD
PL14_02630	ENOG4108JQ7	(ABC) transporter
PL14_02635	ENOG4105C3U	ABC transporter
PL14_02640	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
PL14_02655	ENOG4105BZU	Histidine kinase
PL14_02660	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
PL14_02665	ENOG4105IPI	Membrane
PL14_02670	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
PL14_02675	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
PL14_02690	ENOG4105DR5	peptidase
PL14_02695	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
PL14_02705	ENOG4105CJW	magnesium transporter
PL14_02710	ENOG4106HRJ	d-alanyl-d-alanine carboxypeptidase
PL14_02715	ENOG4105FCK	Membrane
PL14_02720	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
PL14_02725	ENOG4105HBR	Rna-binding protein
PL14_02730	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
PL14_02735	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
PL14_02740	ENOG4105EEI	dihydropteroate synthase
PL14_02765	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
PL14_02770	ENOG4105CHV	Transcription elongation factor NusA
PL14_02775	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
PL14_02780	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
PL14_02785	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
PL14_02790	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
PL14_02795	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
PL14_02805	ENOG41062A4	Transcriptional regulator
PL14_02815	ENOG4106RZ4	Peptidase U32
PL14_02820	ENOG4105CFP	Peptidase U32
PL14_02825	ENOG4105BZU	Histidine kinase
PL14_02830	ENOG4105XPQ	lipid carrier protein
PL14_02835	ENOG4108YYD	acetyltransferase
PL14_02840	ENOG4105VNT	transposase (IS4 family) protein
PL14_02850	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
PL14_02855	ENOG4105BZU	Histidine kinase
PL14_02860	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
PL14_02865	ENOG4105C1J	atp-dependent rna helicase
PL14_02875	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
PL14_02880	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
PL14_02885	ENOG4105CRK	lysyL-tRNA synthetase
PL14_02890	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
PL14_02900	ENOG4105CPC	Aldo Keto reductase
PL14_02905	ENOG4105IRT	Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair (By similarity)
PL14_02910	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
PL14_02915	ENOG4108HRM	phosphoenolpyruvate--protein phosphotransferase
PL14_02920	ENOG4105HF0	Membrane
PL14_02925	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
PL14_02930	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
PL14_02940	ENOG41063Z6	transcriptional regulator, lysR family
PL14_02945	ENOG41080HT	Transcriptional regulator, arsr family
PL14_02950	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
PL14_02955	ENOG4105CJR	Integral membrane protein (MviN
PL14_02960	ENOG4105DTN	riboflavin biosynthesis protein ribF
PL14_02965	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
PL14_02970	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
PL14_02975	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
PL14_02980	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
PL14_02995	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
PL14_03000	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
PL14_03005	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
PL14_03010	ENOG4108NEV	two component transcriptional regulator, LytTR family
PL14_03015	ENOG4108HRK	Histidine kinase
PL14_03020	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
PL14_03035	ENOG4105C5H	ABC transporter
PL14_03040	ENOG4107SC1	transglycosylase
PL14_03045	ENOG4105R9M	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region (By similarity)
PL14_03050	ENOG4108K16	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
PL14_03055	ENOG4108K0B	C-di-gmp phosphodiesterase
PL14_03060	ENOG4107XW0	Spermidine putrescine ABC transporter periplasmic spermidine putrescine-binding protein
PL14_03070	ENOG4108WPH	sigma 54 modulation protein ribosomal protein S30EA
PL14_03075	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
PL14_03080	ENOG4105C34	Pseudouridine synthase
PL14_03085	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
PL14_03090	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
PL14_03135	ENOG4105CFP	Peptidase U32
PL14_03140	ENOG4105DH7	May be involved in recombination (By similarity)
PL14_03145	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
PL14_03150	ENOG4105BZU	Histidine kinase
PL14_03160	ENOG4105C9X	ppx gppa phosphatase
PL14_03165	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
PL14_03170	ENOG4105C8U	phosphate abc transporter
PL14_03175	ENOG4105E2Z	phosphate ABC transporter (Permease
PL14_03180	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
PL14_03190	ENOG4106N3A	copper homeostasis protein cutc
PL14_03195	ENOG4105D3R	alkyl hydroperoxide reductase
PL14_03200	ENOG4105C5Q	Transcriptional regulator
PL14_03205	ENOG4107QP3	malate synthase g
PL14_03210	ENOG4108I9X	Isocitrate lyase
PL14_03215	ENOG4105W87	Cbs domain
PL14_03220	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
PL14_03225	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
PL14_03230	ENOG4105VIE	preprotein translocase, subunit YajC
PL14_03235	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
PL14_03240	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
PL14_03245	ENOG4105ECY	inositol monophosphatase
PL14_03250	ENOG4105CVS	RNA methyltransferase TrmH family, group 1
PL14_03255	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
PL14_03260	ENOG4105C3J	Cysteine desulfurase
PL14_03265	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
PL14_03270	ENOG4108Z4V	iron-sulfur cluster assembly
PL14_03275	ENOG4108SWN	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA (By similarity)
PL14_03280	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
PL14_03285	ENOG4108ZIT	Ferredoxin, 2FE-2S
PL14_03290	ENOG4105WVQ	Fe-S assembly protein IscX
PL14_03295	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
PL14_03300	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
PL14_03310	ENOG4105HSZ	Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis (By similarity)
PL14_03315	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
PL14_03320	ENOG4105CUT	histidyl-tRNA synthetase
PL14_03325	ENOG4105N21	Membrane
PL14_03330	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
PL14_03335	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
PL14_03345	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
PL14_03350	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
PL14_03355	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
PL14_03360	ENOG4105DWF	phosphomethylpyrimidine kinase
PL14_03370	ENOG4106HK8	GPR1 FUN34 yaaH family protein
PL14_03375	ENOG4105BZG	amino acid carrier protein
PL14_03380	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
PL14_03395	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
PL14_03415	ENOG41069H0	dihydroorotase EC 3.5.2.3
PL14_03445	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
PL14_03485	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
PL14_03550	ENOG4108YGG	dna repair protein
PL14_03575	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
PL14_03600	ENOG4105C9U	ATP-dependent DNA helicase RecQ
PL14_03635	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
PL14_03645	ENOG4105DFP	Integrase
PL14_03655	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
PL14_03660	ENOG4108Z1B	Cyclase dehydrase
PL14_03665	ENOG4105VDB	UPF0125 protein
PL14_03670	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
PL14_03675	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
PL14_03680	ENOG4105CIC	tryptophan-specific transport protein
PL14_03685	ENOG4105C0F	tryptophanase EC 4.1.99.1
PL14_03690	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
PL14_03700	ENOG4105CFG	Acts as a chaperone (By similarity)
PL14_03705	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
PL14_03735	ENOG4105CFC	Transporter
PL14_03740	ENOG4105C4W	S-formylglutathione hydrolase
PL14_03750	ENOG4105CC0	LysR family Transcriptional regulator
PL14_03755	ENOG4108Z6B	deaminase
PL14_03760	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
PL14_03765	ENOG4108ETH	Formylglycinamide ribotide synthetase
PL14_03780	ENOG4105W1I	UPF0253 protein
PL14_03785	ENOG4108Q2J	Inner membrane protein YebE
PL14_03790	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
PL14_03795	ENOG4108R96	Methyltransferase, YaeB family
PL14_03800	ENOG4105NRA	50s ribosomal protein l31 type b
PL14_03805	ENOG4108UPT	UPF0178 protein
PL14_03835	ENOG4105WP7	tRNA pseudouridine synthase C
PL14_03840	ENOG4105DR9	pseudouridine synthase
PL14_03845	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
PL14_03850	ENOG4105CTB	Polyprenyl synthetase
PL14_03855	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
PL14_03860	ENOG4105E14	MotA TolQ exbB proton channel
PL14_03865	ENOG4106VK6	Flagellar motor protein
PL14_03870	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
PL14_03875	ENOG4105ETT	transcriptional Regulator, LysR family
PL14_03880	ENOG4105M08	Membrane
PL14_03885	ENOG4105EZ6	Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA (By similarity)
PL14_03890	ENOG4105CIQ	May have a role in processing of nucleic acids. It is probably not an exonuclease
PL14_03895	ENOG4105EWT	decarboxylase family
PL14_03900	ENOG4105FSR	swimming returnes to normal when residues 206-207 are both mutated to Ala. Overexpression also leads to a reduction in flagellar abundance and a 20-fold increase in c-di- GMP levels in vivo. Required for aminoglycoside-mediated induction of biofilm formation, it also plays a lesser role in biofilm production in response to other classes of translation inhibitors. The c-di-GMP produced by this enzyme up-regulates poly-GlcNAc production as well as the biofilm synthesis protein PgaD, although c-di-GMP is probably not the main inducing principle. Cyclic-di- GMP is a second messenger which controls cell surface-associated traits in bacteria
PL14_03910	ENOG4107R1K	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
PL14_03915	ENOG4108T6E	Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function (By similarity)
PL14_03920	ENOG4105EXF	Zn-ribbon-containing, possibly nucleic-acid-binding protein
PL14_03925	ENOG4105D01	(LipO)protein
PL14_03930	ENOG4108UMI	ABC transporter, permease
PL14_03940	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
PL14_03950	ENOG4105D4X	repressor
PL14_03955	ENOG4105C5Y	PTS System
PL14_03960	ENOG4105CG3	alpha amylase, catalytic region
PL14_03965	ENOG4107EXC	regulatoR
PL14_03970	ENOG4105JJR	Histidine kinase
PL14_04005	ENOG410624X	efflux transporter, rnd family, mfp subunit
PL14_04010	ENOG4105BZS	acriflavin resistance protein
PL14_04015	ENOG4105KJF	protein tyrosine phosphatase
PL14_04020	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
PL14_04030	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
PL14_04065	ENOG410600T	transposase
PL14_04070	ENOG4105D7W	serine acetyltransferase
PL14_04080	ENOG4108UHC	Glycosyl transferase, wecb taga cpsf family
PL14_04085	ENOG4108MA4	Peptidase M66
PL14_04105	ENOG4108QV3	biosynthesis protein
PL14_04110	ENOG4105DAY	polysaccharide export protein
PL14_04130	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
PL14_04140	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
PL14_04150	ENOG4108Z43	UPF0250 protein
PL14_04155	ENOG4105DZ1	carboxypeptidase
PL14_04160	ENOG4105K6T	rare lipoprotein A
PL14_04165	ENOG4105CNI	cell division protein FtsW
PL14_04170	ENOG4105CJN	penicillin-binding protein
PL14_04175	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
PL14_04180	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
PL14_04185	ENOG4105DJF	DNA polymerase III, delta' subunit
PL14_04190	ENOG4108U2H	Rare lipoprotein B
PL14_04195	ENOG4105C8T	Leucyl-tRNA synthetase
PL14_04200	ENOG4107PAI	alpha helical protein
PL14_04205	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
PL14_04210	ENOG4108JU5	Magnesium and cobalt efflux protein
PL14_04220	ENOG4105C9A	Phoh family
PL14_04225	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
PL14_04230	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
PL14_04235	ENOG4105C5Y	PTS System
PL14_04240	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
PL14_04245	ENOG4105KZ7	phosphocarrier protein hpr
PL14_04250	ENOG4105C6T	cysteine synthase
PL14_04255	ENOG4105EXN	Sulfate transport protein CysZ
PL14_04260	ENOG4107NPY	receptor for the septal ring structure, may anchor it to the inner-membrane (By similarity)
PL14_04265	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
PL14_04270	ENOG41081QG	Porin Gram-negative type
PL14_04280	ENOG4108Z6Z	Transcriptional regulator
PL14_04290	ENOG4107QX8	SPFH domain, Band 7 family protein
PL14_04295	ENOG4107QR8	Thioredoxin
PL14_04300	ENOG4105ECP	epimerase
PL14_04305	ENOG4108RE9	Phosphodiesterase
PL14_04320	ENOG4108DQ1	activator toxR
PL14_04325	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
PL14_04330	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
PL14_04335	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
PL14_04340	ENOG4105DUX	Transporter
PL14_04345	ENOG4105MDZ	Transcriptional activator rfaH
PL14_04350	ENOG4105CAQ	asparagine synthetase
PL14_04355	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
PL14_04360	ENOG4105E2R	ROK family
PL14_04365	ENOG4105CE4	GlcNAc 6-P deacetylase
PL14_04370	ENOG4105CI1	PTS System
PL14_04375	ENOG4105CX6	glutaminyL-tRNA synthetase
PL14_04385	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
PL14_04390	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
PL14_04395	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
PL14_04400	ENOG4108S3P	Sporulation domain protein
PL14_04405	ENOG4105E96	Colicin v production protein
PL14_04410	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
PL14_04415	ENOG4105D3Y	Na H antiporter
PL14_04420	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
PL14_04425	ENOG4105EIY	sodium-type flagellar protein motY
PL14_04430	ENOG4108UYE	Lactoylglutathione lyase
PL14_04435	ENOG4105CSM	endonuclease III
PL14_04440	ENOG4105DZB	Electron transport complex
PL14_04445	ENOG4108UQQ	Electron transport complex
PL14_04450	ENOG4105D6A	Electron transport complex
PL14_04460	ENOG4108R3D	Electron transport complex
PL14_04475	ENOG4107RBR	Receptor
PL14_04480	ENOG4105E93	esterase
PL14_04500	ENOG4105WQI	isochorismatase
PL14_04505	ENOG4108IQC	2,3-dihydroxybenzoate-AMP ligase
PL14_04510	ENOG4105E4F	Isochorismate synthase
PL14_04515	ENOG4105X17	23-dihydro-2,3-dihydroxybenzoate dehydrogenase
PL14_04520	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
PL14_04530	ENOG4105D05	Receptor
PL14_04545	ENOG410642W	LysR family Transcriptional regulator
PL14_04550	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
PL14_04555	ENOG4105BZS	acriflavin resistance protein
PL14_04560	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
PL14_04570	ENOG4105F27	Major Facilitator
PL14_04575	ENOG4105CHR	reductase
PL14_04590	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
PL14_04595	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
PL14_04605	ENOG4105CHW	UPF0052 protein
PL14_04610	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
PL14_04615	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
PL14_04620	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
PL14_04625	ENOG4105M00	molybdopterin converting factor, subunit 1
PL14_04630	ENOG4108ZAF	Molybdopterin
PL14_04635	ENOG4105BZU	Histidine kinase
PL14_04650	ENOG4108I5U	Uridine phosphorylase
PL14_04660	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
PL14_04665	ENOG4105D1F	ATP-binding protein
PL14_04670	ENOG4105DBI	uridine monophosphokinase
PL14_04675	ENOG4108GAE	asmA family
PL14_04680	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
PL14_04685	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
PL14_04690	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
PL14_04700	ENOG4108AEY	RNA polymerase sigma factor
PL14_04705	ENOG4105CHU	acetyl-coa acetyltransferase
PL14_04710	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
PL14_04715	ENOG41069NU	Nitroreductase
PL14_04720	ENOG4105EJC	lysr family transcriptional regulator
PL14_04725	ENOG4105I93	response regulator
PL14_04730	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
PL14_04735	ENOG4107QMP	dna polymerase iii subunits gamma and tau
PL14_04740	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
PL14_04745	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
PL14_04750	ENOG4105KRS	Proteinase inhibitor
PL14_04755	ENOG4108ZZ3	UPF0260 protein
PL14_04770	ENOG4105DHI	Methyltransferase
PL14_04775	ENOG4105DSB	aldose 1-epimerase
PL14_04785	ENOG4105E0X	reductase
PL14_04795	ENOG4105VUT	cytoplasmic protein
PL14_04800	ENOG4105HDK	L-asparaginase
PL14_04805	ENOG4105D07	Signal peptide peptidase, SppA
PL14_04810	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
PL14_04815	ENOG4105CIY	formyltetrahydrofolate deformylase
PL14_04825	ENOG4105DVT	helicase
PL14_04830	ENOG41072GX	Peptidase M22 Glycoprotease
PL14_04845	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
PL14_04850	ENOG4105CEY	Amp-dependent synthetase and ligase
PL14_04855	ENOG4105ZIE	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity)
PL14_04860	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
PL14_04865	ENOG4107QMS	site-determining protein
PL14_04870	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
PL14_04880	ENOG4105CVE	Lytic murein transglycosylase
PL14_04885	ENOG4105EJC	lysr family transcriptional regulator
PL14_04890	ENOG4105D9N	nucleoside
PL14_04900	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
PL14_04910	ENOG4108VC8	Peptidase family M23
PL14_04915	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
PL14_04925	ENOG4105C3R	Methionine synthase
PL14_04930	ENOG4105C94	Transporter
PL14_04940	ENOG4105C1J	atp-dependent rna helicase
PL14_04950	ENOG4105EJQ	L-serine dehydratase
PL14_04980	ENOG4105CNG	UPF0061 protein
PL14_04985	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
PL14_04990	ENOG4105E0F	Histidine kinase
PL14_04995	ENOG4108JP0	extracellular solute-binding protein family 1
PL14_05005	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
PL14_05010	ENOG410835K	Tripartite ATP-Independent Periplasmic transporter DctQ
PL14_05015	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
PL14_05020	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
PL14_05025	ENOG4105CQZ	Histidine kinase
PL14_05035	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
PL14_05040	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
PL14_05045	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
PL14_05050	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
PL14_05055	ENOG4105K70	DNA-binding protein
PL14_05060	ENOG4105EIN	peptidylprolyl cis-trans isomerase
PL14_05065	ENOG41083P1	competence protein ComEA helix-hairpin-helix repeat protein
PL14_05070	ENOG4105CAT	Cytidine monophosphate kinase
PL14_05075	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
PL14_05080	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
PL14_05085	ENOG4105Q4A	inner membrane protein yciS
PL14_05090	ENOG4105CFV	Tetratricopeptide repeat protein
PL14_05095	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
PL14_05105	ENOG4107R11	Transcriptional regulator
PL14_05115	ENOG4105DCF	alanine dehydrogenase
PL14_05120	ENOG4105EW9	transcriptional regulator AsnC family
PL14_05125	ENOG4105CNU	cell division protein FtsK
PL14_05130	ENOG4105D0M	Protease HtpX homolog
PL14_05140	ENOG4105E1F	short-chain dehydrogenase reductase
PL14_05155	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
PL14_05165	ENOG4105RHG	
PL14_05175	ENOG4105CCT	upf0313 protein
PL14_05185	ENOG4105BZU	Histidine kinase
PL14_05200	ENOG4105DZ2	Transcriptional regulator
PL14_05205	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
PL14_05215	ENOG4105K9H	YciI-like protein
PL14_05220	ENOG4105NAU	thioesterase Superfamily protein
PL14_05225	ENOG4107835	probably involved in intracellular septation (By similarity)
PL14_05235	ENOG4105CK2	sodium dicarboxylate symporter
PL14_05245	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
PL14_05250	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
PL14_05255	ENOG4105DK0	Indole-3-glycerol phosphate synthase
PL14_05260	ENOG4108I0Q	anthranilate phosphoribosyltransferase
PL14_05265	ENOG4105DDQ	anthranilate synthase
PL14_05270	ENOG4105CRQ	synthase (Component I)
PL14_05280	ENOG4105DB7	PHP domain protein
PL14_05285	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
PL14_05290	ENOG4105FE9	pseudouridine synthase
PL14_05295	ENOG4108JJ8	(ABC) transporter
PL14_05300	ENOG4108JJ9	ABC, transporter
PL14_05305	ENOG4105C3M	thioredoxin reductase
PL14_05310	ENOG4105BZU	Histidine kinase
PL14_05320	ENOG4105C9B	Cysteine desulfurase
PL14_05325	ENOG4107GZ4	SanA protein
PL14_05335	ENOG4107R1I	NAD-dependent malic enzyme
PL14_05345	ENOG4105C8V	SAICAR synthetase
PL14_05355	ENOG41090BQ	Glutaredoxin
PL14_05365	ENOG4106KNT	transcriptional regulator
PL14_05370	ENOG4105DY8	decarboxylase
PL14_05380	ENOG4105DWU	Membrane
PL14_05405	ENOG4105BZU	Histidine kinase
PL14_05415	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
PL14_05420	ENOG4107QTF	adenylosuccinate lyase
PL14_05425	ENOG41075W9	High frequency lysogenization protein HflD homolog
PL14_05430	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
PL14_05440	ENOG4107RE1	Inosine-guanosine kinase
PL14_05445	ENOG4108SAU	DNA-binding protein H-ns
PL14_05450	ENOG4107S6Z	Na H antiporter
PL14_05455	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
PL14_05460	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
PL14_05465	ENOG4105CIH	Imidazole acetol-phosphate transaminase
PL14_05470	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
PL14_05485	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
PL14_05490	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
PL14_05495	ENOG4108R99	pseudouridine synthase
PL14_05505	ENOG4105VEQ	Cold shock protein
PL14_05510	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
PL14_05515	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
PL14_05520	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
PL14_05525	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
PL14_05530	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
PL14_05535	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
PL14_05540	ENOG4105RKX	Protein of unknown function (DUF2498)
PL14_05545	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
PL14_05550	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
PL14_05555	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
PL14_05575	ENOG4105HP8	regulator of competence-specific genes
PL14_05580	ENOG4105ETE	Transcriptional regulator (LacI family
PL14_05585	ENOG4109039	Involved in the biogenesis of TorA. Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor (By similarity)
PL14_05590	ENOG4106WF9	DNA-binding transcriptional regulator TorR
PL14_05595	ENOG4107S90	membrAne
PL14_05600	ENOG4106371	Methyltransferase
PL14_05605	ENOG4105GHU	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity (By similarity)
PL14_05610	ENOG4105DAH	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF (By similarity)
PL14_05615	ENOG4105DUC	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division (By similarity)
PL14_05630	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
PL14_05635	ENOG4105PFA	Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity)
PL14_05640	ENOG4105DA6	Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity)
PL14_05645	ENOG41081XQ	Conserved Protein
PL14_05650	ENOG4105C9M	aspartyl-trna synthetase
PL14_05655	ENOG4107104	thymidine kinase
PL14_05665	ENOG4105GFG	DUF218 domain
PL14_05690	ENOG4105TMB	Formate nitrite transporter
PL14_05705	ENOG4108J2R	molybdopterin oxidoreductase
PL14_05715	ENOG4105E2M	Manganese-dependent inorganic pyrophosphatase
PL14_05725	ENOG4105C4R	Atp-dependent dna helicase
PL14_05760	ENOG4108JQ2	peptide transport system atp-binding protein
PL14_05765	ENOG4108JQ3	Peptide ABC transporter ATP-binding protein
PL14_05770	ENOG4108EU3	peptide transport system, permease
PL14_05775	ENOG4108I5W	peptide transport system, permease protein
PL14_05780	ENOG4108J59	Extracellular solute-binding protein, family 5
PL14_05785	ENOG4105E51	psp operon transcriptional activator
PL14_05790	ENOG41087YS	Phage shock protein A
PL14_05795	ENOG4105YYT	phage shock protein B
PL14_05805	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
PL14_05810	ENOG4105C28	cystathionine
PL14_05820	ENOG4105C8J	)-transporter
PL14_05825	ENOG4108W1A	pseudouridine synthase
PL14_05835	ENOG4105CXC	rtn protein
PL14_05840	ENOG4108T9J	Cdp-alcohol phosphatidyltransferase
PL14_05845	ENOG4108VGW	abc transporter atp-binding protein
PL14_05850	ENOG4105CXZ	ABC transporter, permease
PL14_05855	ENOG4105VNH	ABC transporter solute-binding protein
PL14_05865	ENOG4105XZD	Fe-S protein
PL14_05875	ENOG4107RNS	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic
PL14_05885	ENOG4105C1J	atp-dependent rna helicase
PL14_05900	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
PL14_05905	ENOG4105EB3	Histidine kinase
PL14_05920	ENOG4105CFI	type iii restriction protein res subunit
PL14_05925	ENOG4105I08	Pseudouridine synthase
PL14_05930	ENOG4105C2C	drug resistance transporter, Bcr CflA
PL14_05940	ENOG4105CGD	Nad-dependent epimerase dehydratase
PL14_05945	ENOG4105UQX	Mate efflux family protein
PL14_05950	ENOG4108I0Y	(ABC) transporter
PL14_05965	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
PL14_05985	ENOG4105D3D	Catalyzes the decarboxylation of carboxynorspermidine and carboxyspermidine (By similarity)
PL14_05990	ENOG4108NVR	Methyl-accepting chemotaxis
PL14_06020	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
PL14_06025	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
PL14_06030	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
PL14_06035	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
PL14_06040	ENOG4108N3W	hemolysin secretion protein
PL14_06045	ENOG4105EIP	mannose-6-phosphate isomerase
PL14_06050	ENOG4105DM4	PTS System
PL14_06055	ENOG4108CIP	transcriptional regulator
PL14_06065	ENOG4108YRF	PTS System
PL14_06075	ENOG4105VYW	UPF0251 protein
PL14_06100	ENOG4107SDZ	Galactoside transport system permease protein mglC
PL14_06110	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
PL14_06115	ENOG41080IJ	Diacylglycerol kinase
PL14_06120	ENOG4105GR3	Histidine kinase
PL14_06125	ENOG4107EXC	regulatoR
PL14_06155	ENOG4105CR4	methylisocitrate lyase
PL14_06160	ENOG4105BZN	citrate synthase
PL14_06165	ENOG4108I0Z	Aconitate hydratase
PL14_06170	ENOG4105C7F	AcnD-accessory protein PrpF
PL14_06175	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
PL14_06190	ENOG410667J	hydrolase
PL14_06195	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
PL14_06200	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
PL14_06225	ENOG4105DR4	Methyltransferase
PL14_06230	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
PL14_06235	ENOG4108Z0T	Part of a sulfur-relay system (By similarity)
PL14_06240	ENOG4108MN8	Membrane
PL14_06245	ENOG4105CDA	abc transporter atp-binding protein
PL14_06250	ENOG4105DRP	amino acid AbC transporter
PL14_06255	ENOG4105EZ7	amino acid ABC transporter
PL14_06260	ENOG4107QXX	ABC transporter
PL14_06265	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
PL14_06270	ENOG4105BZU	Histidine kinase
PL14_06280	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
PL14_06285	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
PL14_06300	ENOG4105QNR	S1 RNA binding domain protein
PL14_06305	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
PL14_06310	ENOG4108RS6	transposase
PL14_06315	ENOG4105DY2	Paraquat-inducible protein b
PL14_06320	ENOG4105H2K	paraquat-inducible protein a
PL14_06325	ENOG4105BZ1	(ABC) transporter
PL14_06330	ENOG4108ZGC	gaf domain protein
PL14_06335	ENOG41073DY	may be a structural element that influences the osmotic activation of ProP at a post-translational level (By similarity)
PL14_06340	ENOG4105CN1	protease
PL14_06350	ENOG4105CD8	aminopeptidase N
PL14_06360	ENOG4105C7I	Dehydrogenase
PL14_06365	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
PL14_06370	ENOG4108T7E	Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ (By similarity)
PL14_06375	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
PL14_06385	ENOG4105C5H	ABC transporter
PL14_06400	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
PL14_06405	ENOG4105DAN	ATP-dependent protease
PL14_06410	ENOG4108R9Q	Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle. Prevents early segregation of duplicated Ter macrodomains during cell division. Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain (By similarity)
PL14_06460	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
PL14_06475	ENOG4105D6P	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex (By similarity)
PL14_06485	ENOG4105C59	p-type ATPase
PL14_06500	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
PL14_06505	ENOG4105Q9Y	Universal stress protein
PL14_06510	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
PL14_06530	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
PL14_06535	ENOG4105F38	ABC transporter, permease
PL14_06540	ENOG4105D38	putrescine abc transporter
PL14_06545	ENOG4107RUE	extracellular solute-binding protein family 1
PL14_06550	ENOG4107RUE	extracellular solute-binding protein family 1
PL14_06555	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
PL14_06565	ENOG4105C5H	ABC transporter
PL14_06570	ENOG4108KX4	response regulator
PL14_06575	ENOG4105BZU	Histidine kinase
PL14_06580	ENOG4105CXY	transporter
PL14_06585	ENOG4105C4Y	ABC transporter
PL14_06590	ENOG4107RCV	ABC transporter, permease
PL14_06595	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
PL14_06600	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
PL14_06605	ENOG4105FNP	Molybdopterin-guanine dinucleotide biosynthesis protein b
PL14_06615	ENOG4105EZX	Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P (By similarity)
PL14_06620	ENOG4106IUH	DTW domain containing protein
PL14_06630	ENOG4108N3W	hemolysin secretion protein
PL14_06635	ENOG4107TT5	NLP P60 protein
PL14_06645	ENOG4105FGM	Fructosamine kinase
PL14_06655	ENOG4107QI1	Mate efflux family protein
PL14_06665	ENOG4108NRW	Phospholipase, patatin family
PL14_06680	ENOG4109015	Biopolymer transport protein exbD tolR
PL14_06720	ENOG4108RXX	maleylacetoacetate isomerase
PL14_06730	ENOG4105F1J	Homogentisate 1,2-dioxygenase
PL14_06735	ENOG4105E6K	4-Hydroxyphenylpyruvate dioxygenase
PL14_06740	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
PL14_06750	ENOG4105BZG	amino acid carrier protein
PL14_06755	ENOG410829K	Lysine exporter protein (Lyse ygga)
PL14_06760	ENOG4105CTD	carboxy-peptidase
PL14_06765	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
PL14_06770	ENOG4108R4R	Iron-regulated virulence regulatory protein
PL14_06780	ENOG4105CQ7	ATP-dependent helicase
PL14_06800	ENOG4105BZU	Histidine kinase
PL14_06810	ENOG4105CFG	Acts as a chaperone (By similarity)
PL14_06815	ENOG4105CFG	Acts as a chaperone (By similarity)
PL14_06845	ENOG4105DDV	Transcriptional regulator (LacI family
PL14_06850	ENOG4105CS2	ec 3.2.1.21
PL14_06855	ENOG4105C1J	atp-dependent rna helicase
PL14_06860	ENOG4107QY8	reductase
PL14_06865	ENOG4105CUW	cytochrome C-TYPE protein
PL14_06870	ENOG4105VEQ	Cold shock protein
PL14_06875	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
PL14_06880	ENOG4105BZU	Histidine kinase
PL14_06885	ENOG4105C8P	)-transporter
PL14_06890	ENOG4108NVR	Methyl-accepting chemotaxis
PL14_06895	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
PL14_06905	ENOG4105BZU	Histidine kinase
PL14_06915	ENOG4105D9U	N-acetyltransferase
PL14_06920	ENOG4108JU8	Transcriptional regulator
PL14_06925	ENOG4106K28	UPF0283 membrane protein
PL14_06930	ENOG4105CM6	amino acid regulated cytosolic protein
PL14_06945	ENOG4105CRQ	synthase (Component I)
PL14_06950	ENOG4105P8F	nudix hydrolase
PL14_06955	ENOG4105C44	Serine transporter
PL14_06960	ENOG4105EJQ	L-serine dehydratase
PL14_06970	ENOG4108K8S	endonuclease I
PL14_06975	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
PL14_06980	ENOG4105C8Q	Methyl-accepting chemotaxis
PL14_06985	ENOG4105C5S	asparaginyl-tRNA synthetase
PL14_06995	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
PL14_07000	ENOG4108Z4W	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
PL14_07005	ENOG4105BZU	Histidine kinase
PL14_07010	ENOG4108V3W	Chemotaxis protein, CheW
PL14_07020	ENOG4105CBS	Chea signal transduction histidine kinase
PL14_07030	ENOG4108VYJ	response regulator receiver protein
PL14_07035	ENOG4108NVR	Methyl-accepting chemotaxis
PL14_07040	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
PL14_07045	ENOG4105CGF	Aromatic amino acid aminotransferase
PL14_07050	ENOG41080XQ	Signal transduction protein with cbs domains
PL14_07060	ENOG4105C8Q	Methyl-accepting chemotaxis
PL14_07065	ENOG4105C94	Transporter
PL14_07070	ENOG41067TZ	transcriptional regulator, MarR family
PL14_07085	ENOG4105C5X	domain protein
PL14_07090	ENOG4105EAQ	(twin-arginine translocation) pathway signal
PL14_07095	ENOG4105DIT	ErfK YbiS YcfS YnhG family protein
PL14_07120	ENOG4107T1C	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity)
PL14_07125	ENOG4105DKQ	ROK family
PL14_07135	ENOG4105PYN	Pyridoxamine 5-phosphate oxidase-related
PL14_07140	ENOG41090JE	Utilization Protein
PL14_07145	ENOG4105WQ5	TonB family
PL14_07150	ENOG41090AP	transport protein
PL14_07155	ENOG4106GFD	transport protein
PL14_07165	ENOG4105EHG	Permease protein
PL14_07170	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
PL14_07175	ENOG4105C72	UPF0176 protein
PL14_07185	ENOG4105C8Q	Methyl-accepting chemotaxis
PL14_07190	ENOG41068WN	
PL14_07200	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
PL14_07225	ENOG4107R3K	hydrolase
PL14_07235	ENOG4105C5Y	PTS System
PL14_07240	ENOG4105D7K	pfkb domain protein
PL14_07245	ENOG4105BZU	Histidine kinase
PL14_07255	ENOG4105C8Q	Methyl-accepting chemotaxis
PL14_07260	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
PL14_07265	ENOG4105C4M	(Ubiquinol oxidase) subunit I
PL14_07290	ENOG4105E18	UPF0276 protein
PL14_07305	ENOG4105C4M	(Ubiquinol oxidase) subunit I
PL14_07310	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
PL14_07320	ENOG4105M4H	endoribonuclease L-psp
PL14_07350	ENOG41090WB	Transposase is3 is911
PL14_07360	ENOG4107VQW	regulatoR
PL14_07385	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
PL14_07390	ENOG4105C26	Dehydrogenase
PL14_07475	ENOG4108UW8	fha domain-containing protein
PL14_07500	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
PL14_07570	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
PL14_07595	ENOG4105BZU	Histidine kinase
PL14_07615	ENOG4107R88	Chemotaxis protein (CheV)
PL14_07625	ENOG4106YYS	transcriptional regulatory protein
PL14_07630	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
PL14_07645	ENOG4107V40	secretion protein, HlyD family
PL14_07665	ENOG4105CVG	Homoserine O-transsuccinylase
PL14_07670	ENOG41090FY	type IV pilus biogenesis stability protein PilW
PL14_07685	ENOG4108VKG	metal-dependent hydrolase
PL14_07695	ENOG4107RSM	transcriptional regulator
PL14_07715	ENOG41080WI	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system (By similarity)
PL14_07720	ENOG4108ESU	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane (By similarity)
PL14_07735	ENOG4108YZT	Adenosylcobinamide kinase
PL14_07740	ENOG4108UHF	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
PL14_07745	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
PL14_07750	ENOG4105EUK	rtx toxin RtxA
PL14_07755	ENOG4108RC6	RTX toxin
PL14_07770	ENOG4105C42	Type I secretion membrane fusion protein (HlyD
PL14_07780	ENOG4105C8Q	Methyl-accepting chemotaxis
PL14_07785	ENOG4105K4T	epimerase
PL14_07790	ENOG4108ETY	sodium dicarboxylate symporter
PL14_07795	ENOG4105CJB	Exodeoxyribonuclease I
PL14_07805	ENOG41067MG	lrgb family
PL14_07810	ENOG4107T42	This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis (By similarity)
PL14_07815	ENOG4105BZU	Histidine kinase
PL14_07820	ENOG4108HH9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
PL14_07825	ENOG4107SDU	Methyl-accepting chemotaxis
PL14_07830	ENOG4105FQ6	thiopurine methyltransferase
PL14_07840	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
PL14_07845	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
PL14_07850	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
PL14_07890	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
PL14_07895	ENOG4105WH1	Two component transcriptional regulator luxr family
PL14_07900	ENOG4105CQ2	DNA polymerase
PL14_07910	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
PL14_07925	ENOG4105CZE	histidine utilization repressor
PL14_07935	ENOG41088SP	formiminoglutamate hydrolase
PL14_07940	ENOG4105CGP	Urocanate hydratase
PL14_07945	ENOG4105C84	Histidine ammonia-lyase
PL14_07960	ENOG4105CQB	FAD linked oxidase domain protein
PL14_07995	ENOG4107QPN	acyl-Coa dehydrogenase
PL14_08000	ENOG41067SE	Tetr family transcriptional regulator
PL14_08015	ENOG4105C26	Dehydrogenase
PL14_08020	ENOG4105BZU	Histidine kinase
PL14_08035	ENOG4108RNS	Exports L-alanine (By similarity)
PL14_08040	ENOG4105BZU	Histidine kinase
PL14_08050	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
PL14_08055	ENOG4105UFD	tol-pal system protein YbgF
PL14_08060	ENOG4105KCK	Peptidoglycan-associated lipoprotein
PL14_08065	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
PL14_08075	ENOG4105M8F	Biopolymer transport protein exbD tolR
PL14_08080	ENOG4105E02	MotA TolQ exbB proton channel
PL14_08085	ENOG4107YD3	Thioesterase
PL14_08090	ENOG4105KJB	cyd operon protein YbgE
PL14_08100	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
PL14_08105	ENOG4105C4M	(Ubiquinol oxidase) subunit I
PL14_08110	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
PL14_08115	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
PL14_08120	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
PL14_08130	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
PL14_08135	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
PL14_08140	ENOG4105D58	Diguanylate phosphodiesterase
PL14_08145	ENOG4105K5B	UPF0225 protein
PL14_08160	ENOG4105DVT	helicase
PL14_08170	ENOG4108URS	primosomal replication protein n''
PL14_08175	ENOG4106428	Protein of unknown function (DUF2496)
PL14_08180	ENOG4105C8Q	Methyl-accepting chemotaxis
PL14_08185	ENOG4105CGK	Exodeoxyribonuclease III
PL14_08190	ENOG4106YG3	ABC transporter
PL14_08195	ENOG4105DSP	amino acid AbC transporter
PL14_08200	ENOG4105E89	ABC transporter
PL14_08205	ENOG4108JEH	abc transporter atp-binding protein
PL14_08220	ENOG4105C6N	Formate acetyltransferase
PL14_08230	ENOG4108NVR	Methyl-accepting chemotaxis
PL14_08245	ENOG4105F1A	Pyruvate formate-lyase
PL14_08255	ENOG4105XWI	UPF0304 protein
PL14_08260	ENOG4105CYN	Serine protein kinase
PL14_08265	ENOG4106AKX	UPF0229 protein
PL14_08270	ENOG4105ED1	spovr family
PL14_08275	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
PL14_08280	ENOG4105W49	UPF0434 protein
PL14_08285	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
PL14_08290	ENOG4105BZ1	(ABC) transporter
PL14_08295	ENOG4108EQH	DNA internalization-related competence protein ComEC Rec2
PL14_08305	ENOG4105D60	lipoprotein releasing system transmembrane protein
PL14_08310	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
PL14_08315	ENOG4105D60	lipoprotein releasing system transmembrane protein
PL14_08325	ENOG4108JA2	transcriptioN-repair coupling factor
PL14_08335	ENOG4106M3D	hemolysin
PL14_08340	ENOG4105CEP	NADH dehydrogenase
PL14_08345	ENOG4105D0Y	UPF0227 protein
PL14_08370	ENOG4105K59	histidine triad (HIT) protein
PL14_08375	ENOG4108NVR	Methyl-accepting chemotaxis
PL14_08385	ENOG4105C05	Multifunctional regulator of fatty acid metabolism (By similarity)
PL14_08395	ENOG410635M	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
PL14_08400	ENOG4105EWW	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
PL14_08405	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
PL14_08410	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
PL14_08415	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
PL14_08420	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
PL14_08425	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
PL14_08430	ENOG4105D1H	recombination factor protein RarA
PL14_08435	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
PL14_08445	ENOG4105FBT	Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity)
PL14_08450	ENOG4108JJB	ABC transporter
PL14_08455	ENOG4105C7J	ABC transporter, permease
PL14_08465	ENOG4105PQ6	UPF0208 membrane protein
PL14_08470	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
PL14_08475	ENOG4108DNC	Involved in acetate metabolism (By similarity)
PL14_08480	ENOG4105CHF	Glutathione S-transferase
PL14_08485	ENOG4108JQ7	(ABC) transporter
PL14_08490	ENOG4105C3U	ABC transporter
PL14_08495	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
PL14_08500	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
PL14_08505	ENOG4107QSI	ABC, transporter
PL14_08510	ENOG4105BZU	Histidine kinase
PL14_08515	ENOG4105BZU	Histidine kinase
PL14_08540	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
PL14_08565	ENOG4107QJZ	Glycosyl transferase, family 2
PL14_08570	ENOG4105C84	Histidine ammonia-lyase
PL14_08600	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
PL14_08605	ENOG4105C2D	reductase
PL14_08610	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
PL14_08615	ENOG4105RW8	MltA-interacting MipA family protein
PL14_08625	ENOG4106TD9	Diguanylate cyclase
PL14_08635	ENOG4108UHU	Aldolase
PL14_08640	ENOG4105C6Z	Gluconate
PL14_08645	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
PL14_08650	ENOG4105C01	Dihydroxy-acid dehydratase
PL14_08655	ENOG4105DIQ	Transcriptional regulator
PL14_08665	ENOG4105BZU	Histidine kinase
PL14_08675	ENOG4105D0C	transport protein
PL14_08685	ENOG4105EW9	transcriptional regulator AsnC family
PL14_08690	ENOG4105DIJ	Phosphoethanolamine transferase
PL14_08695	ENOG4105DHQ	Histidine kinase
PL14_08710	ENOG4105EMU	Dehydrogenase
PL14_08720	ENOG4108IQE	Amp-dependent synthetase and ligase
PL14_08780	ENOG4107QTH	restriction modification system DNA specificity domain
PL14_08800	ENOG4108F3G	Type I restriction-modification system, R subunit
PL14_08805	ENOG4105F6A	helicase
PL14_08840	ENOG4106TD9	Diguanylate cyclase
PL14_08855	ENOG4108MNP	Glycoprotein polysaccharide metabolism
PL14_08860	ENOG4105C29	acyl-CoA thioesterase
PL14_08865	ENOG4108XM1	transcriptional regulator AsnC family
PL14_08900	ENOG4105CEY	Amp-dependent synthetase and ligase
PL14_08905	ENOG4105DNI	Converts SHCHC to OSB (By similarity)
PL14_08910	ENOG4108IPT	Naphthoate synthase
PL14_08920	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
PL14_08925	ENOG4105E4F	Isochorismate synthase
PL14_08930	ENOG4105CHM	Aminotransferase
PL14_08935	ENOG4105DK2	UPF0207 protein
PL14_08940	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
PL14_08955	ENOG4105ERU	peptidase
PL14_08960	ENOG4105UBK	short-chain dehydrogenase reductase
PL14_08965	ENOG4107R88	Chemotaxis protein (CheV)
PL14_08970	ENOG4105DAG	ROK family
PL14_08975	ENOG4105CA9	Pyruvate kinase
PL14_08980	ENOG4108NRW	Phospholipase, patatin family
PL14_08990	ENOG4105C8J	)-transporter
PL14_08995	ENOG4105CI1	PTS System
PL14_09000	ENOG4105F8V	Hydrolase, tatD family
PL14_09005	ENOG4107QRG	dna polymerase iii
PL14_09010	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
PL14_09015	ENOG4105HHA	aminodeoxychorismate lyase
PL14_09020	ENOG4105YAZ	4-amino-4-deoxychorismate lyase
PL14_09025	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
PL14_09030	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
PL14_09035	ENOG4105CHR	reductase
PL14_09040	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
PL14_09045	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
PL14_09050	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
PL14_09055	ENOG4105VGS	50s ribosomal protein l32
PL14_09060	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
PL14_09065	ENOG4108UHJ	MAF-like protein
PL14_09070	ENOG4105EI2	Pseudouridine synthase
PL14_09075	ENOG4105C03	ribonuclease
PL14_09085	ENOG4108EKI	Dehydrogenase
PL14_09090	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
PL14_09095	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
PL14_09100	ENOG4105DFD	Na H antiporter
PL14_09110	ENOG4106V8H	Nucleoid-associated protein
PL14_09115	ENOG4105YDX	UPF0352 protein
PL14_09120	ENOG4105E68	Sulfatase
PL14_09130	ENOG4107QKC	Oxidoreductase alpha (molybdopterin) subunit
PL14_09135	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
PL14_09150	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
PL14_09155	ENOG4105M2J	Glutaredoxin
PL14_09160	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
PL14_09175	ENOG410903C	(LipO)protein
PL14_09185	ENOG4108M1T	Cytochrome c-type biogenesis protein
PL14_09190	ENOG4107QX9	Thiol disulfide interChange protein
PL14_09195	ENOG4105DA4	cytochrome c-type biogenesis protein
PL14_09200	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
PL14_09210	ENOG41060IM	Heme exporter protein
PL14_09215	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
PL14_09230	ENOG4108V3W	Chemotaxis protein, CheW
PL14_09240	ENOG4107QJE	Chromosome Partitioning Protein
PL14_09245	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
PL14_09250	ENOG4105CBS	Chea signal transduction histidine kinase
PL14_09255	ENOG4108KCC	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity)
PL14_09260	ENOG4108VYJ	response regulator receiver protein
PL14_09265	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
PL14_09270	ENOG4107R21	site-determining protein
PL14_09275	ENOG4105FZW	flagellar biosynthesis regulator FlhF
PL14_09280	ENOG4105D7B	Flagellar biosynthesis protein flha
PL14_09285	ENOG4108BY2	phosphohistidine phosphatase
PL14_09290	ENOG4108JQM	Insulinase (Peptidase family M16)
PL14_09295	ENOG4106ZCM	YecM protein
PL14_09300	ENOG4105C75	arginyL-tRNA synthetase
PL14_09320	ENOG4105XFK	Ferrous iron transport protein A
PL14_09325	ENOG4107S4Z	Activates expression of the rhaBAD and rhaT operons (By similarity)
PL14_09330	ENOG4105NXV	High-affinity zinc uptake system protein
PL14_09335	ENOG4105FDK	ABC transporter
PL14_09340	ENOG4105FAV	ABC, transporter
PL14_09345	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
PL14_09350	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
PL14_09355	ENOG4105C7S	Dehydrogenase
PL14_09360	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
PL14_09365	ENOG4105E33	succinate dehydrogenase
PL14_09370	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
PL14_09375	ENOG4105N1I	succinate dehydrogenase, hydrophobic membrane anchor protein
PL14_09380	ENOG4108UTY	succinate dehydrogenase, cytochrome b556 subunit
PL14_09385	ENOG4105BZN	citrate synthase
PL14_09390	ENOG4107QNR	UPF0135 protein
PL14_09400	ENOG4107QIX	Phosphoglucomutase (EC 5.4.2.2
PL14_09405	ENOG4107CDU	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated (By similarity)
PL14_09410	ENOG4105EV9	Alpha Beta Hydrolase
PL14_09420	ENOG4105MHQ	Low-potential electron donor to a number of redox enzymes (By similarity)
PL14_09425	ENOG41067MG	lrgb family
PL14_09430	ENOG4105VAW	lrga family
PL14_09435	ENOG4105CMU	LysR family (Transcriptional regulator
PL14_09445	ENOG41090R7	Ferric uptake
PL14_09450	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
PL14_09455	ENOG4105CJ0	Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate (By similarity)
PL14_09460	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
PL14_09465	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
PL14_09470	ENOG4105Q8W	reductase
PL14_09475	ENOG4105MH2	YfcL protein
PL14_09480	ENOG4108BPE	-transporting atpase
PL14_09485	ENOG4105EN6	Membrane
PL14_09490	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
PL14_09495	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
PL14_09500	ENOG4108DG9	Smr protein MutS2
PL14_09505	ENOG4105D00	flagellar biosynthetic protein flhB
PL14_09510	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
PL14_09515	ENOG4105VS8	Flagellar biosynthetic protein fliq
PL14_09520	ENOG4105CN7	Flagellar biosynthetic protein FliP
PL14_09525	ENOG4105VTB	flagellar biosynthesis protein fliO
PL14_09530	ENOG4105DD5	Flagellar motor switch protein
PL14_09535	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
PL14_09555	ENOG4108JIR	Flagellum-specific ATP synthase
PL14_09565	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
PL14_09570	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
PL14_09575	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
PL14_09580	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
PL14_09585	ENOG4105BZU	Histidine kinase
PL14_09590	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
PL14_09595	ENOG4105MQ3	flagellar protein FliS
PL14_09605	ENOG4107BRV	flagellar capping protein
PL14_09610	ENOG41063QE	flagellar protein FlaG
PL14_09615	ENOG4105I03	Flagellin
PL14_09620	ENOG4105I03	Flagellin
PL14_09625	ENOG4105I03	Flagellin
PL14_09630	ENOG4105EZR	dyp-type peroxidase family protein
PL14_09635	ENOG4105QZU	Inner membrane protein YfeZ
PL14_09655	ENOG4105KUZ	arsenate reductase
PL14_09660	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
PL14_09675	ENOG4107EG0	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
PL14_09680	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
PL14_09715	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
PL14_09740	ENOG4105EJC	lysr family transcriptional regulator
PL14_09755	ENOG4105C8Q	Methyl-accepting chemotaxis
PL14_09770	ENOG4105ERG	peptidase m48, ste24p
PL14_09775	ENOG4105K89	arsenate reductase
PL14_09780	ENOG4105CS1	NAD(P)H quinone oxidoreductase
PL14_09795	ENOG4105C2W	permease
PL14_09800	ENOG4108Z66	YbaK ebsC protein
PL14_09805	ENOG4105CGH	5'-nucleotidase
PL14_09810	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
PL14_09815	ENOG41063JG	Transcriptional regulator
PL14_09820	ENOG4108YY7	Invasion gene expression up-regulator SirB
PL14_09825	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
PL14_09830	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
PL14_09835	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
PL14_09845	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
PL14_09850	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
PL14_09855	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
PL14_09860	ENOG4105C3G	gtp-binding protein
PL14_09945	ENOG4105I03	Flagellin
PL14_09950	ENOG4105I03	Flagellin
PL14_09955	ENOG4105DTJ	flagellar hook-associated protein
PL14_09965	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
PL14_09970	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
PL14_09975	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
PL14_09980	ENOG4105CGA	flagellar basal-body rod protein FlgG
PL14_09985	ENOG4108KPB	Flagellar basal-body rod protein FlgF
PL14_09990	ENOG4105BZE	flagellar hook protein, FlgE
PL14_09995	ENOG4105W00	Flagellar hook capping protein
PL14_10000	ENOG4108ZC9	flagellar basal-body rod protein flgc
PL14_10005	ENOG4105K88	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
PL14_10010	ENOG4105BZU	Histidine kinase
PL14_10015	ENOG4107R88	Chemotaxis protein (CheV)
PL14_10060	ENOG4105UYK	outer membrane protein a
PL14_10065	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
PL14_10070	ENOG4105C59	p-type ATPase
PL14_10080	ENOG4105E2D	ec 3.2.1.52
PL14_10090	ENOG4105FE9	pseudouridine synthase
PL14_10095	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
PL14_10100	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
PL14_10105	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
PL14_10110	ENOG4105E7A	Glutamine amidotransferase
PL14_10115	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
PL14_10120	ENOG4107QPN	acyl-Coa dehydrogenase
PL14_10130	ENOG4108JDX	DNA polymerase iii, epsilon subunit
PL14_10135	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
PL14_10140	ENOG4105D1A	Methyltransferase
PL14_10145	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
PL14_10150	ENOG4105E9H	Lytic Murein transglycosylase
PL14_10165	ENOG4108YZA	Nitrogen regulatory protein pii
PL14_10170	ENOG4105N7H	Cytochrome
PL14_10175	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
PL14_10180	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
PL14_10185	ENOG4105C0B	DNA polymerase III (alpha subunit)
PL14_10190	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
PL14_10195	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
PL14_10200	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
PL14_10205	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
PL14_10210	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
PL14_10215	ENOG4108RFI	Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm (By similarity)
PL14_10225	ENOG4105DZP	Membrane-associated zinc metalloprotease
PL14_10230	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
PL14_10235	ENOG4105KNE	Phosphatidate cytidylyltransferase
PL14_10240	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
PL14_10245	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
PL14_10250	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
PL14_10255	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
PL14_10260	ENOG4105CE9	30S ribosomal protein S2
PL14_10265	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
PL14_10270	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
PL14_10275	ENOG4108T8E	UPF0325 protein
PL14_10280	ENOG4108ZAI	phosphatidylglycerophosphatase a
PL14_10285	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
PL14_10290	ENOG4107YIM	Involved in the transcription termination process (By similarity)
PL14_10295	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
PL14_10310	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
PL14_10315	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
PL14_10320	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
PL14_10325	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
PL14_10330	ENOG4108UVK	Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes. Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32 (By similarity)
PL14_10335	ENOG4108DJV	Fermentation respiration switch protein
PL14_10340	ENOG4105DYA	Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity)
PL14_10345	ENOG4105C7N	Xanthine uracil vitamin C permease
PL14_10350	ENOG4105CIN	aminoacyl-histidine dipeptidase
PL14_10355	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
PL14_10360	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
PL14_10370	ENOG4105C8J	)-transporter
PL14_10385	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
PL14_10395	ENOG4105CJ2	(LipO)protein
PL14_10400	ENOG4105D26	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway (By similarity)
PL14_10405	ENOG4108IUB	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
PL14_10410	ENOG4105F5D	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
PL14_10415	ENOG4106I92	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
PL14_10420	ENOG4108J5C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
PL14_10425	ENOG4105DWQ	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
PL14_10430	ENOG4105M85	Bola protein
PL14_10435	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
PL14_10445	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
PL14_10450	ENOG4105EYM	Major Facilitator superfamily
PL14_10460	ENOG4105K6V	RNA polymerase
PL14_10475	ENOG4108JZF	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
PL14_10480	ENOG4107S0N	DJ-1 family
PL14_10485	ENOG4105C9B	Cysteine desulfurase
PL14_10490	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
PL14_10495	ENOG4105CUZ	uba thif-type nad fad binding protein
PL14_10500	ENOG4105CA3	membrane-bound lytic murein transglycosylase
PL14_10510	ENOG4107QZM	n-acetylglutamate synthase
PL14_10520	ENOG4107QYX	exodeoxyribonuclease v alpha
PL14_10525	ENOG4107QKA	exodeoxyribonuclease V beta
PL14_10530	ENOG4105DSY	exodeoxyribonuclease V, gamma
PL14_10545	ENOG4105X2V	dna damage-inducible protein
PL14_10550	ENOG4105EJ3	Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA (By similarity)
PL14_10580	ENOG41060NJ	transcriptional regulator
PL14_10590	ENOG4105F0Z	galactose-1-phosphate uridylyltransferase
PL14_10595	ENOG4105CMR	udp-glucose 4-epimerase
PL14_10600	ENOG4105UQX	Mate efflux family protein
PL14_10610	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
PL14_10620	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
PL14_10630	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
PL14_10640	ENOG4105EAC	phosphoserine phosphatase
PL14_10650	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
PL14_10655	ENOG4105CZG	Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity)
PL14_10660	ENOG4105CMW	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity)
PL14_10670	ENOG4105D9N	nucleoside
PL14_10675	ENOG4105EYA	deoxyribonuclease
PL14_10680	ENOG4105D1Q	UPF0246 protein
PL14_10685	ENOG4105BZG	amino acid carrier protein
PL14_10700	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
PL14_10705	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
PL14_10710	ENOG4108VKA	Acts as a radical domain for damaged PFL and possibly other radical proteins (By similarity)
PL14_10715	ENOG4105D98	threonine synthase
PL14_10720	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
PL14_10735	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
PL14_10740	ENOG41065U4	response regulator
PL14_10750	ENOG4105BZU	Histidine kinase
PL14_10755	ENOG4105N5T	Radical SAM Protein
PL14_10770	ENOG4105CBC	glutamate synthase
PL14_10775	ENOG4105BZ8	glutamate synthase
PL14_10785	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
PL14_10795	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
PL14_10800	ENOG4105EN6	Membrane
PL14_10805	ENOG4105VP0	transcriptional regulator, lysR family
PL14_10810	ENOG4105EJ9	Membrane
PL14_10815	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
PL14_10820	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
PL14_10825	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
PL14_10830	ENOG4105M6F	mutator MutT protein
PL14_10835	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
PL14_10845	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
PL14_10850	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
PL14_10855	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
PL14_10860	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
PL14_10865	ENOG4105DFU	Cell wall formation (By similarity)
PL14_10870	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
PL14_10880	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
PL14_10885	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
PL14_10890	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
PL14_10895	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
PL14_10900	ENOG4105CJN	penicillin-binding protein
PL14_10905	ENOG41063Y6	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
PL14_10910	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
PL14_10920	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
PL14_10925	ENOG4105E1C	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a) (By similarity)
PL14_10930	ENOG41082RQ	UPF0102 protein
PL14_10935	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
PL14_10940	ENOG4105W4M	Transport-associated protein
PL14_10945	ENOG4105KB2	stringent starvation protein b
PL14_10950	ENOG4107MKT	Stringent starvation protein a
PL14_10955	ENOG4105EIX	cytochrome c1
PL14_10960	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
PL14_10965	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
PL14_10970	ENOG4108UJD	30S ribosomal protein S9
PL14_10975	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
PL14_10985	ENOG4105D6Z	AFG1 family ATPase
PL14_10990	ENOG4108W2Q	Cytochrome d ubiquinol oxidase subunit III
PL14_10995	ENOG4105C0H	protease
PL14_11000	ENOG4105C0H	protease
PL14_11005	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
PL14_11010	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
PL14_11015	ENOG4105IPS	esterase
PL14_11020	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
PL14_11025	ENOG4108SX3	cytoplasmic protein
PL14_11030	ENOG41087AY	ADP-Ribose pyrophosphatase
PL14_11035	ENOG4105DFG	type I secretion outer membrane protein
PL14_11045	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
PL14_11050	ENOG4108NVR	Methyl-accepting chemotaxis
PL14_11060	ENOG4105I7R	Adenylate cyclase
PL14_11065	ENOG4107IX6	phosphate transport regulator
PL14_11070	ENOG4105CJ3	phosphate transporter
PL14_11075	ENOG4106MWK	domain protein
PL14_11090	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
PL14_11095	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
PL14_11100	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
PL14_11105	ENOG4105DXN	mazG family
PL14_11110	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
PL14_11115	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
PL14_11120	ENOG4105BZU	Histidine kinase
PL14_11125	ENOG4105KJV	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
PL14_11130	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
PL14_11135	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
PL14_11140	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
PL14_11145	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
PL14_11150	ENOG4105C3F	Signal peptidase i
PL14_11155	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
PL14_11160	ENOG4105WMJ	Positive regulator of sigma E, RseC MucC
PL14_11175	ENOG4105EMN	RNA polymerase sigma factor
PL14_11180	ENOG4108IYU	L-aspartate oxidase
PL14_11190	ENOG4105Y75	tpr repeat protein
PL14_11195	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
PL14_11210	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
PL14_11215	ENOG4105D0A	hydroxylase
PL14_11225	ENOG4107YUN	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
PL14_11235	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
PL14_11240	ENOG4105E66	phosphoriboisomerase A
PL14_11245	ENOG4108JQ1	Dehydrogenase
PL14_11250	ENOG4108ZP8	Acetolactate synthase small subunit
PL14_11255	ENOG4105C7K	acetolactate synthase
PL14_11260	ENOG4108IQE	Amp-dependent synthetase and ligase
PL14_11265	ENOG41064T2	transcriptional regulator, lysR family
PL14_11280	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
PL14_11290	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
PL14_11295	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
PL14_11350	ENOG4108K5H	permease YjgP YjgQ family protein
PL14_11355	ENOG4108M8S	permease YjgP YjgQ family protein
PL14_11360	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
PL14_11365	ENOG4105MYG	DNA polymerase iii, chi subunit
PL14_11370	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
PL14_11375	ENOG4105C5I	Dehydrogenase
PL14_11380	ENOG4105D3G	Pseudouridine synthase
PL14_11385	ENOG4105K3M	)-transporter
PL14_11390	ENOG4105BZK	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity)
PL14_11395	ENOG4108IAB	Phoh family
PL14_11400	ENOG4105DBV	ornithine carbamoyltransferase
PL14_11405	ENOG4105CXT	aspartate transcarbamylase
PL14_11410	ENOG4108R9M	Involved in allosteric regulation of aspartate carbamoyltransferase (By similarity)
PL14_11415	ENOG4105KME	endoribonuclease L-psp
PL14_11430	ENOG4107S7E	1-acyl-sn-glycerol-3-phosphate acyltransferase
PL14_11435	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
PL14_11440	ENOG4105VFK	BolA family
PL14_11450	ENOG4105E3I	toluene tolerance
PL14_11455	ENOG4107PE3	Mammalian cell entry related domain protein
PL14_11460	ENOG4105CY3	ABC transporter, permease
PL14_11465	ENOG4105DHJ	ABC, transporter
PL14_11475	ENOG4105C2X	Arabinose 5-phosphate isomerase
PL14_11480	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
PL14_11490	ENOG4105WI0	lipopolysaccharide transport periplasmic protein lptA
PL14_11495	ENOG4108IUZ	ABC transporter
PL14_11500	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
PL14_11505	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
PL14_11510	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
PL14_11520	ENOG41080Z8	PHOSPHOCARRIER protein
PL14_11525	ENOG4105CJW	magnesium transporter
PL14_11530	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
PL14_11535	ENOG4105N42	UPF0307 protein
PL14_11540	ENOG4107T0D	ABC, transporter
PL14_11545	ENOG4106SMU	thiamine transporter membrane protein
PL14_11550	ENOG4105DP9	ABC transporter
PL14_11555	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
PL14_11560	ENOG4105DFU	Cell wall formation (By similarity)
PL14_11565	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
PL14_11570	ENOG4105F0N	pyrophosphate phospho-hydrolase
PL14_11575	ENOG41066HZ	AIG2-like family
PL14_11580	ENOG4105MA0	exported protein
PL14_11585	ENOG4105CFU	surface antigen
PL14_11590	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
PL14_11595	ENOG4108UUE	Transcriptional regulator
PL14_11630	ENOG4108I67	Catalyzes the synthesis of activated sulfate (By similarity)
PL14_11635	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
PL14_11640	ENOG4105C11	sulfate adenylyltransferase), subunit 2
PL14_11645	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
PL14_11650	ENOG4107RNS	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic
PL14_11690	ENOG4105C1J	atp-dependent rna helicase
PL14_11695	ENOG4107YB6	acetyltransferase, (GNAT) family
PL14_11700	ENOG4108UBT	opacity-associated protein
PL14_11705	ENOG4108V1T	peptidylprolyl cis-trans isomerase
PL14_11710	ENOG4108ZT0	50S ribosomal protein l17
PL14_11715	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
PL14_11720	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
PL14_11725	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
PL14_11730	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
PL14_11740	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
PL14_11745	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
PL14_11750	ENOG4105VPB	50S ribosomal protein L30
PL14_11755	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
PL14_11765	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
PL14_11770	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
PL14_11775	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
PL14_11780	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
PL14_11790	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
PL14_11795	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
PL14_11800	ENOG41083MP	50s ribosomal protein l29
PL14_11805	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
PL14_11810	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
PL14_11815	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
PL14_11820	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
PL14_11825	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
PL14_11830	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
PL14_11835	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
PL14_11840	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
PL14_11845	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
PL14_11850	ENOG4105C2N	RNA methyltransferase TrmH family group 3
PL14_11855	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
PL14_11860	ENOG4108UV7	flagellar protein motX
PL14_11865	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
PL14_11870	ENOG4105D44	asparaginase
PL14_11875	ENOG4108YZY	peptidylprolyl cis-trans isomerase
PL14_11880	ENOG4105VKU	nucleicacid-binding protein
PL14_11890	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
PL14_11895	ENOG4105C5H	ABC transporter
PL14_11905	ENOG4105DNZ	Alpha Beta Hydrolase
PL14_11910	ENOG4105YP7	UPF0270 protein
PL14_11915	ENOG4105CJE	phosphoribulokinase (EC 2.7.1.19)
PL14_11920	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
PL14_11930	ENOG4105C26	Dehydrogenase
PL14_11945	ENOG4105DDQ	anthranilate synthase
PL14_11980	ENOG410600T	transposase
PL14_11990	ENOG410600T	transposase
PL14_12015	ENOG410600T	transposase
PL14_12035	ENOG4105CR8	Transcriptional regulator
PL14_12050	ENOG4105C31	Tryptophanyl-tRNA synthetase
PL14_12055	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
PL14_12060	ENOG4105DJV	ribulose-phosphate 3-epimerase
PL14_12065	ENOG4105DFE	Dna adenine methylase
PL14_12075	ENOG4105D49	3-dehydroquinate synthase
PL14_12080	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
PL14_12085	ENOG4105E4G	Type IV pilus
PL14_12110	ENOG4108JQC	penicillin-binding protein 1A
PL14_12115	ENOG4105VNT	transposase (IS4 family) protein
PL14_12120	ENOG4105C5Q	Transcriptional regulator
PL14_12125	ENOG4105EHV	domain protein
PL14_12130	ENOG4107QN2	dihydrolipoyl dehydrogenase
PL14_12140	ENOG4105CH7	arginosuccinase
PL14_12145	ENOG4105CDH	Citrulline--aspartate ligase
PL14_12150	ENOG4105CAS	nag kinase
PL14_12155	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
PL14_12160	ENOG4105CWC	Acetylornithine deacetylase
PL14_12165	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
PL14_12175	ENOG4105D7W	serine acetyltransferase
PL14_12180	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
PL14_12185	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
PL14_12190	ENOG4107YZP	Rhodanese domain protein
PL14_12195	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
PL14_12210	ENOG4108WJH	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity)
PL14_12215	ENOG4108VP9	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity)
PL14_12220	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
PL14_12225	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
PL14_12240	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
PL14_12245	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
PL14_12270	ENOG4105CP7	Triose-phosphate isomerase
PL14_12275	ENOG4107QMU	Mate efflux family protein
PL14_12280	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
PL14_12285	ENOG4105EIS	1,4-dihydroxy-2-naphthoate octaprenyltransferase
PL14_12290	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
PL14_12295	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
PL14_12305	ENOG4105ETE	Transcriptional regulator (LacI family
PL14_12310	ENOG4105C25	Primosomal protein n'
PL14_12315	ENOG4105VFB	Binds the 23S rRNA (By similarity)
PL14_12320	ENOG4105C6K	Malic enzyme
PL14_12325	ENOG4105VNT	transposase (IS4 family) protein
PL14_12330	ENOG4105GGQ	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis (By similarity)
PL14_12335	ENOG4105C28	cystathionine
PL14_12340	ENOG4105CFH	Aspartokinase
PL14_12345	ENOG4105SYT	Methylenetetrahydrofolate reductase
PL14_12350	ENOG41065UX	Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA (By similarity)
PL14_12355	ENOG4105CBT	Fructose-1,6-bisphosphatase
PL14_12360	ENOG4105CTQ	phosphohexokinase
PL14_12365	ENOG41076HS	cation diffusion facilitator family transporter
PL14_12375	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
PL14_12380	ENOG4105E0F	Histidine kinase
PL14_12385	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
PL14_12390	ENOG4105VEQ	Cold shock protein
PL14_12395	ENOG4108YH1	overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7
PL14_12405	ENOG4108IJ0	Aspartate ammonia-lyase
PL14_12410	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
PL14_12415	ENOG4105CSX	c4-dicarboxylate anaerobic carrier
PL14_12420	ENOG4105CEU	Arginine dihydrolase
PL14_12430	ENOG4105DBV	ornithine carbamoyltransferase
PL14_12440	ENOG4105CXT	aspartate transcarbamylase
PL14_12445	ENOG4108R9M	Involved in allosteric regulation of aspartate carbamoyltransferase (By similarity)
PL14_12450	ENOG410682Y	Regulates arginine biosynthesis genes (By similarity)
PL14_12455	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
PL14_12465	ENOG4105C3N	Participates in control of cell volume in low-osmolarity conditions (By similarity)
PL14_12475	ENOG4107QN1	sodium solute
PL14_12480	ENOG4105BZU	Histidine kinase
PL14_12485	ENOG4105D8G	Major Facilitator superfamily
PL14_12505	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
PL14_12510	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
PL14_12515	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
PL14_12525	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
PL14_12530	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
PL14_12540	ENOG4105CXN	decarboxylase
PL14_12545	ENOG4105D5Q	Arginine ornithine antiporter
PL14_12550	ENOG4107XGF	functions in a salvage pathway. Uses pyridoxamine (By similarity)
PL14_12555	ENOG4108M3R	transcriptional activator CadC
PL14_12560	ENOG4105W1Y	Transcriptional regulator
PL14_12565	ENOG4105DC1	bifunctional purine biosynthesis protein purh
PL14_12570	ENOG4105C12	Phosphoribosylglycinamide synthetase
PL14_12580	ENOG4105K70	DNA-binding protein
PL14_12590	ENOG4105WDY	DNA (cytosine-5-)-methyltransferase
PL14_12600	ENOG4105R2J	Conserved Protein
PL14_12605	ENOG4105JPG	D-isomer specific 2-hydroxyacid dehydrogenase
PL14_12610	ENOG4105CUY	Mechanosensitive ion channel
PL14_12615	ENOG4105C8Q	Methyl-accepting chemotaxis
PL14_12620	ENOG4105CY0	Metallo-Beta-Lactamase
PL14_12630	ENOG410600T	transposase
PL14_12640	ENOG410600T	transposase
PL14_12660	ENOG4107QRS	glycosyltransferase group 2 family protein
PL14_12690	ENOG4107ZF2	Phosphatase
PL14_12695	ENOG4105DAY	polysaccharide export protein
PL14_12705	ENOG4108MDC	(LipO)protein
PL14_12715	ENOG4105E3R	(LipO)protein
PL14_12725	ENOG4105D3Q	Sugar transferase
PL14_12745	ENOG4105H63	Glycosyl transferase, family 2
PL14_12750	ENOG4106IQQ	
PL14_12780	ENOG4105CKK	Glycosyl transferase, family 2
PL14_12795	ENOG4105C7K	acetolactate synthase
PL14_12805	ENOG4105DF3	Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta-cleavage pathway for the degradation of aromatic compounds (By similarity)
PL14_12815	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
PL14_12820	ENOG4105FAW	cDP-glucose 4,6-dehydratase
PL14_12825	ENOG4105EJZ	Glucose-1-phosphate cytidylyltransferase
PL14_12855	ENOG4105EY8	ABC transporter
PL14_12865	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
PL14_12875	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
PL14_12880	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
PL14_12885	ENOG4105CUI	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity)
PL14_12895	ENOG4105PF3	O-Antigen polymerase
PL14_12900	ENOG4105XA0	heptosyltransferase ii
PL14_12910	ENOG4108ST3	glycosyltransferase
PL14_12915	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
PL14_12920	ENOG4108UT6	Transferase hexapeptide repeat containing protein
PL14_12925	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
PL14_12940	ENOG4108W7E	Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position (By similarity)
PL14_12945	ENOG4105DKP	glycosyl transferase, family 9
PL14_12950	ENOG4106WTF	Glycosyl transferase, family 2
PL14_12955	ENOG4105M5K	heptosyltransferase
PL14_12960	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
PL14_12965	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
PL14_12975	ENOG4105W0E	50S ribosomal protein L33
PL14_12980	ENOG4105KDC	50s ribosomal protein l28
PL14_12990	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
PL14_12995	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
PL14_13000	ENOG4105D1S	lipid A biosynthesis
PL14_13005	ENOG4105NWR	lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase
PL14_13010	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
PL14_13015	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
PL14_13020	ENOG4105DSJ	YicC domain protein
PL14_13030	ENOG4107RAN	Peptidase, M16
PL14_13055	ENOG4105C5Y	PTS System
PL14_13060	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
PL14_13065	ENOG4108PSC	Represses the expression of the murPQ operon involved in the uptake and degradation of N-acetylmuramic acid (MurNAc). Binds to two adjacent inverted repeats within the operator region. MurNAc 6-phosphate, the substrate of MurQ, is the specific inducer that weakens binding of MurR to the operator (By similarity)
PL14_13080	ENOG4105C9U	ATP-dependent DNA helicase RecQ
PL14_13085	ENOG4105FR1	rard protein
PL14_13090	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
PL14_13100	ENOG4105CCF	Lysine exporter protein (Lyse ygga)
PL14_13105	ENOG4105C4R	Atp-dependent dna helicase
PL14_13110	ENOG4105DGW	oligopeptidase A
PL14_13115	ENOG4105D6S	protein involved in catabolism of external DNA
PL14_13120	ENOG4105DC8	reductase
PL14_13125	ENOG4108VYJ	response regulator receiver protein
PL14_13140	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
PL14_13145	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
PL14_13185	ENOG4105MPD	Cytochrome
PL14_13190	ENOG4105C4R	Atp-dependent dna helicase
PL14_13195	ENOG4107Z3H	Transcriptional regulator, TetR family
PL14_13200	ENOG410624X	efflux transporter, rnd family, mfp subunit
PL14_13205	ENOG4105BZS	acriflavin resistance protein
PL14_13210	ENOG4105W0Z	cytoplasmic protein
PL14_13215	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
PL14_13220	ENOG4105EMY	transcriptional regulator
PL14_13225	ENOG4105D4P	Coproporphyrinogen iii oxidase
PL14_13230	ENOG4105XCT	Protein of unknown function (DUF2489)
PL14_13235	ENOG4105ZR3	A GTPase-activating protein (GAP) that modifies Der EngA GTPase function. May play a role in ribosome biogenesis (By similarity)
PL14_13250	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
PL14_13255	ENOG4105C2M	dna polymerase I
PL14_13260	ENOG4105D52	delta-aminolevulinic acid dehydratase
PL14_13270	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
PL14_13275	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
PL14_13280	ENOG4105WKS	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
PL14_13285	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
PL14_13290	ENOG4105JC1	sterol-binding domain protein
PL14_13295	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
PL14_13300	ENOG4105CGY	Dna recombination protein
PL14_13305	ENOG4108TVT	permease
PL14_13310	ENOG4105BZU	Histidine kinase
PL14_13325	ENOG4105EQR	Transposase IS116 IS110 IS902
PL14_13340	ENOG410600T	transposase
PL14_13360	ENOG4105EQR	Transposase IS116 IS110 IS902
PL14_13390	ENOG4105CBX	hi0933 family
PL14_13400	ENOG4108V6B	universal stress protein B
PL14_13405	ENOG41090A1	ferritin
PL14_13410	ENOG4108M6U	Universal stress protein A
PL14_13415	ENOG4105EMK	carboxylate amino acid amine transporter
PL14_13425	ENOG4105FFN	Specifically methylates the guanosine in position 1516 of 16S rRNA (By similarity)
PL14_13430	ENOG4108VVK	transcriptional Regulator, AsnC
PL14_13440	ENOG4105CNH	Multidrug resistance protein MdtL
PL14_13445	ENOG4105G2Y	Transcriptional regulator
PL14_13450	ENOG4105DC7	peptidase M24
PL14_13450	ENOG4105DC7	peptidase M24
PL14_13455	ENOG4105D41	biosynthesis protein thiH
PL14_13460	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
PL14_13465	ENOG4105WHD	thiamine biosynthesis protein ThiS
PL14_13470	ENOG4105D06	uba thif-type nad fad binding protein
PL14_13475	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
PL14_13480	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
PL14_13485	ENOG4105WMR	Protein CrcB homolog
PL14_13555	ENOG4108RR8	protoporphyrinogen oxidase
PL14_13560	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
PL14_13565	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
PL14_13570	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
PL14_13575	ENOG4105CHU	acetyl-coa acetyltransferase
PL14_13580	ENOG4105F52	Transcriptional regulator
PL14_13585	ENOG4105CZQ	inner membrane transport protein YdhC
PL14_13590	ENOG4105VNT	transposase (IS4 family) protein
PL14_13595	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
PL14_13600	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
PL14_13605	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
PL14_13610	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
PL14_13615	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
PL14_13620	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
PL14_13630	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
PL14_13635	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
PL14_13640	ENOG410684E	atp synthase
PL14_13645	ENOG4105FA0	parb-like partition protein
PL14_13650	ENOG4107QJE	Chromosome Partitioning Protein
PL14_13655	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
PL14_13660	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
PL14_13665	ENOG4105QTB	Flavodoxin
PL14_13670	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
PL14_13675	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
PL14_13680	ENOG4105NVJ	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
PL14_13690	ENOG4105CDA	abc transporter atp-binding protein
PL14_13695	ENOG4105E5Q	amino acid AbC transporter
PL14_13700	ENOG4105EAB	amino acid AbC transporter
PL14_13760	ENOG4108ZJT	translation initiation factor, Sui1
PL14_13775	ENOG4105CPF	Cell wall formation (By similarity)
PL14_13785	ENOG4105CD5	CoA-binding domain protein
PL14_13790	ENOG4105CWB	LysR family transcriptional Regulator
PL14_13830	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
PL14_13840	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
PL14_13845	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
PL14_13860	ENOG4105FSR	swimming returnes to normal when residues 206-207 are both mutated to Ala. Overexpression also leads to a reduction in flagellar abundance and a 20-fold increase in c-di- GMP levels in vivo. Required for aminoglycoside-mediated induction of biofilm formation, it also plays a lesser role in biofilm production in response to other classes of translation inhibitors. The c-di-GMP produced by this enzyme up-regulates poly-GlcNAc production as well as the biofilm synthesis protein PgaD, although c-di-GMP is probably not the main inducing principle. Cyclic-di- GMP is a second messenger which controls cell surface-associated traits in bacteria
PL14_13865	ENOG4105VEQ	Cold shock protein
PL14_13875	ENOG4105C8Q	Methyl-accepting chemotaxis
PL14_13890	ENOG410848D	S4 domain protein YaaA
PL14_13895	ENOG4105CYM	Glutathione S-transferase
PL14_13900	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
PL14_13905	ENOG4105C5H	ABC transporter
PL14_13920	ENOG4105KA0	thioesterase Superfamily protein
PL14_13930	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
PL14_13940	ENOG4105DU1	integral membrane protein, terc
PL14_13945	ENOG4105CGH	5'-nucleotidase
PL14_13950	ENOG4105CPB	ATP-dependent endonuclease of the OLD family
PL14_13955	ENOG4108UQ5	membrane protein YcdZ
PL14_13960	ENOG4105DUM	transcriptional regulator, lysR family
PL14_13965	ENOG4105TMB	Formate nitrite transporter
PL14_13975	ENOG4105DUX	Transporter
PL14_13985	ENOG4108K85	Transcriptional regulator
PL14_13990	ENOG4105NXH	GreA GreB family elongation factor
PL14_13995	ENOG4105PAD	Hydrolase
PL14_14000	ENOG4105DZ0	fad dependent oxidoreductase
PL14_14005	ENOG4108Z4U	Ferredoxin
PL14_14015	ENOG4105CKU	formyltetrahydrofolate synthetase
PL14_14020	ENOG4105E0X	reductase
PL14_14030	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
PL14_14035	ENOG4105D06	uba thif-type nad fad binding protein
PL14_14040	ENOG4105KHC	sulfurtransferase
PL14_14055	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
PL14_14075	ENOG4108V1T	peptidylprolyl cis-trans isomerase
PL14_14080	ENOG4107VXZ	Hydrolase
PL14_14085	ENOG4108N3W	hemolysin secretion protein
PL14_14090	ENOG4108YYC	ycei family
PL14_14095	ENOG4105DS1	cytochrome b561
PL14_14120	ENOG4108JQ5	ABC transporter
PL14_14125	ENOG4108IYQ	Binding-protein-dependent transport systems inner membrane component
PL14_14130	ENOG4108I5X	binding-protein-dependent transport systems inner membrane Component
PL14_14135	ENOG4105E43	Extracellular solute-binding protein, family 5
PL14_14150	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
PL14_14155	ENOG4105CGF	Aromatic amino acid aminotransferase
PL14_14160	ENOG4108RDD	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity)
PL14_14165	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
PL14_14170	ENOG4105BZU	Histidine kinase
PL14_14195	ENOG41080HT	Transcriptional regulator, arsr family
PL14_14210	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
PL14_14215	ENOG4105BZU	Histidine kinase
PL14_14225	ENOG4105BZU	Histidine kinase
PL14_14235	ENOG4108VYJ	response regulator receiver protein
PL14_14260	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
PL14_14265	ENOG4105E0C	molybdate abc transporter
PL14_14270	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
PL14_14275	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
PL14_14280	ENOG4105WXI	Bacterial OB fold (BOF) protein
PL14_14290	ENOG4105BZU	Histidine kinase
PL14_14295	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
PL14_14305	ENOG4105CF7	AraC family transcriptional regulator
PL14_14310	ENOG4108I6A	alcohol dehydrogenase
PL14_14315	ENOG4107TXD	phosphoglycerate transport system transcriptional regulatory protein pgta
PL14_14345	ENOG4108QYW	Bacterial hemolysins are exotoxins that attack blood cell membranes and cause cell rupture. Beta-hemolysin is a phospholipase C with specific activity toward sphingomyelins. Has a high specificity for sphingomyelin, hydrolyzes lysophosphatidylcholine at a much lower rate, but has no activity towards phosphatidylcholine, phosphatidylethanolamine, or phosphatidylserine (By similarity)
PL14_14350	ENOG4105BZU	Histidine kinase
PL14_14355	ENOG4108SV3	Tmao reductase system periplasmic protein tort
PL14_14360	ENOG4108Z5K	methylglyoxal synthase
PL14_14365	ENOG41088T4	Helicase IV
PL14_14370	ENOG4105EM2	membrane
PL14_14390	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
PL14_14400	ENOG4105BZU	Histidine kinase
PL14_14405	ENOG410600T	transposase
PL14_14415	ENOG4108QGH	periplasmic
PL14_14425	ENOG41082IR	Excinuclease ABC C subunit domain protein
PL14_14440	ENOG41090HJ	UPF0265 protein
PL14_14450	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
PL14_14455	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
PL14_14460	ENOG4107R5Y	anaerobic glycerol-3-phosphate dehydrogenase, subunit A
PL14_14465	ENOG4108KJ0	anaerobic glycerol-3-phosphate dehydrogenase, subunit B
PL14_14470	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
PL14_14475	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
PL14_14490	ENOG4105EKQ	RNA-directed DNA polymerase
PL14_14495	ENOG4105VNT	transposase (IS4 family) protein
PL14_14525	ENOG4108MBX	Secretion Protein
PL14_14555	ENOG4105CAF	HipA N-terminal domain protein
PL14_14565	ENOG4105CC0	LysR family Transcriptional regulator
PL14_14590	ENOG4105K63	Thioredoxin
PL14_14600	ENOG4105VXR	cytoplasmic protein
PL14_14610	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
PL14_14615	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
PL14_14625	ENOG4105WZK	nitrite reductase NADPH small subunit
PL14_14630	ENOG4107QZF	nitrite reductase NADPH large subunit
PL14_14635	ENOG4105CHJ	isochorismatase hydrolase
PL14_14640	ENOG4105CXN	decarboxylase
PL14_14690	ENOG4105EV2	VWA domain protein interacting with AAA ATPase
PL14_14705	ENOG4105C5W	Aldolase
PL14_14715	ENOG4105C1J	atp-dependent rna helicase
PL14_14720	ENOG4105E0U	tyrosine-specific transport protein
PL14_14725	ENOG4108NVR	Methyl-accepting chemotaxis
PL14_14730	ENOG4105CMR	udp-glucose 4-epimerase
PL14_14735	ENOG4105E7W	lamb ycsf family protein
PL14_14755	ENOG4105CV6	ABC transporter, permease
PL14_14760	ENOG4108I0Y	(ABC) transporter
PL14_14770	ENOG4105RKW	reductase (By
PL14_14785	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
PL14_14800	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
PL14_14850	ENOG4107RE1	Inosine-guanosine kinase
PL14_14855	ENOG4105BZU	Histidine kinase
PL14_14870	ENOG4105C8Q	Methyl-accepting chemotaxis
PL14_14875	ENOG4105CYW	agmatinase
PL14_14880	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
PL14_14890	ENOG4108IJ7	Glycine betaine
PL14_14895	ENOG4108HQS	Glycine betaine
PL14_14900	ENOG4105GIJ	Glycine betaine
PL14_14915	ENOG4105CJW	magnesium transporter
PL14_14920	ENOG4105CZK	Aspartate kinase
PL14_14925	ENOG4108Z6K	Catalyzes the circularization of gamma-N-acetyl- alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6- tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant (By similarity)
PL14_14930	ENOG4108JPW	Aminotransferase
PL14_14935	ENOG4108Z24	l-2,4-diaminobutyric acid acetyltransferase
PL14_14945	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
PL14_14950	ENOG4107RA1	nh(3)-dependent nad( ) synthetase
PL14_14980	ENOG4105C8Q	Methyl-accepting chemotaxis
PL14_15000	ENOG4105C8Q	Methyl-accepting chemotaxis
PL14_15005	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
PL14_15040	ENOG4105FSR	swimming returnes to normal when residues 206-207 are both mutated to Ala. Overexpression also leads to a reduction in flagellar abundance and a 20-fold increase in c-di- GMP levels in vivo. Required for aminoglycoside-mediated induction of biofilm formation, it also plays a lesser role in biofilm production in response to other classes of translation inhibitors. The c-di-GMP produced by this enzyme up-regulates poly-GlcNAc production as well as the biofilm synthesis protein PgaD, although c-di-GMP is probably not the main inducing principle. Cyclic-di- GMP is a second messenger which controls cell surface-associated traits in bacteria
PL14_15050	ENOG4105N1F	Hnh endonuclease
PL14_15055	ENOG4105VRT	cytoplasmic protein
PL14_15060	ENOG4105E0M	Sulfatase
PL14_15070	ENOG41080IJ	Diacylglycerol kinase
PL14_15075	ENOG4105D4Y	metalloprotease
PL14_15085	ENOG4105CSW	GntR family transcriptional regulator
PL14_15090	ENOG4108RPX	mosc domain containing protein
PL14_15115	ENOG4105CPQ	Dehydrogenase
PL14_15120	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
PL14_15125	ENOG4105EXG	Transcriptional regulator
PL14_15130	ENOG4108YZK	glyoxalase bleomycin resistance protein dioxygenase
PL14_15140	ENOG4105CXY	transporter
PL14_15145	ENOG4108KX4	response regulator
PL14_15150	ENOG4105BZU	Histidine kinase
PL14_15155	ENOG4105CXY	transporter
PL14_15165	ENOG4105HVQ	Regulatory factor of maltose metabolism
PL14_15175	ENOG4108WTW	DNA transposition protein
PL14_15240	ENOG4105KUS	lysozyme
PL14_15420	ENOG4105CPI	Metal Dependent Phosphohydrolase
PL14_15440	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
PL14_15445	ENOG41082YX	Transcriptional regulator, arsr family
PL14_15450	ENOG4105D6J	arsenicaL-resistance protein
PL14_15455	ENOG41082YX	Transcriptional regulator, arsr family
PL14_15460	ENOG4105CHH	sulfate transporter
PL14_15475	ENOG4105BZU	Histidine kinase
PL14_15485	ENOG4108W3Q	Transcriptional regulator
PL14_15490	ENOG4105ID8	Transcriptional regulator, ARAC family
PL14_15495	ENOG4107ZSV	Receptor
PL14_15500	ENOG4105EYM	Major Facilitator superfamily
PL14_15505	ENOG4105C0W	non-ribosomal peptide synthetase
PL14_15530	ENOG4108IQC	2,3-dihydroxybenzoate-AMP ligase
PL14_15535	ENOG4105BZ1	(ABC) transporter
PL14_15540	ENOG4105BZ1	(ABC) transporter
PL14_15575	ENOG4105E3J	oxidoreductase
PL14_15580	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
PL14_15585	ENOG4105ECM	Sensor protein basS pmrB
PL14_15590	ENOG4105EQD	regulatoR
PL14_15640	ENOG4105EJC	lysr family transcriptional regulator
PL14_15665	ENOG4107R4Q	Functions as an ATPase. May play a role in metal insertion (metal-chelatase) or as a chaperone (By similarity)
PL14_15700	ENOG4108YUH	
PL14_15710	ENOG4105CVR	type I restriction-modification system
PL14_15775	ENOG4105CS6	Rhs element vgr protein
PL14_15780	ENOG4108WC9	type VI secretion system effector, hcp1 family
PL14_15820	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
PL14_15825	ENOG4105C5I	Dehydrogenase
PL14_15850	ENOG4105VEQ	Cold shock protein
PL14_15855	ENOG4108VWS	Yaeq family
PL14_15860	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
PL14_15865	ENOG4108JUA	Transcriptional regulator
PL14_15875	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
PL14_15880	ENOG4105D9N	nucleoside
PL14_15885	ENOG4105QVC	MOSC domain-containing protein
PL14_15890	ENOG4105EKE	dihydroorotase
PL14_15895	ENOG4107SFS	Catalyzes the formation of 5-methyl-uridine at position 747 (m5U747) in 23S rRNA (By similarity)
PL14_15900	ENOG4105CKW	Inner membrane protein yedI
PL14_15925	ENOG4105BZU	Histidine kinase
PL14_15930	ENOG4105E98	transcriptional regulator DeoR family
PL14_15935	ENOG4105VJY	transcriptional regulator
PL14_15940	ENOG4105NNS	Autoinducer synthesis protein
PL14_15955	ENOG4105EG2	ABC transporter, permease
PL14_15960	ENOG4105D56	permease protein
PL14_15965	ENOG4107FKK	extracellular solute-binding protein family 1
PL14_15970	ENOG4108IJ9	(ABC) transporter
PL14_15975	ENOG41086KC	Transcriptional regulator
PL14_15980	ENOG4105KQ5	peptidylprolyl cis-trans isomerase
PL14_15985	ENOG4107R88	Chemotaxis protein (CheV)
PL14_15990	ENOG4105MSB	protein, conserved in bacteria
PL14_15995	ENOG4106TD9	Diguanylate cyclase
PL14_16010	ENOG4105BZU	Histidine kinase
PL14_16030	ENOG4108K0B	C-di-gmp phosphodiesterase
PL14_16040	ENOG4105EUB	pirin domain protein
PL14_16050	ENOG4105NBK	UPF0345 protein
PL14_16060	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
PL14_16070	ENOG4105E5Q	amino acid AbC transporter
PL14_16075	ENOG4106TNF	Periplasmic binding protein
PL14_16080	ENOG4105DRP	amino acid AbC transporter
PL14_16100	ENOG4105FBJ	fumarylacetoacetate (faa) hydrolase
PL14_16110	ENOG4108SXK	Transporter Drug Metabolite Exporter family
PL14_16125	ENOG4105E5M	Multidrug resistance protein D
PL14_16130	ENOG4105EQ2	LysR family Transcriptional regulator
PL14_16140	ENOG4105DR5	peptidase
PL14_16150	ENOG4105CHH	sulfate transporter
PL14_16155	ENOG4105DWD	nucleoside recognition domain protein
PL14_16170	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
PL14_16175	ENOG4105E2Z	phosphate ABC transporter (Permease
PL14_16180	ENOG4105C8U	phosphate abc transporter
PL14_16185	ENOG4105CVA	phosphate
PL14_16195	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
PL14_16200	ENOG4108HK0	-acetyltransferase
PL14_16215	ENOG4105D4Y	metalloprotease
PL14_16220	ENOG4105EIF	outer membrane protein W
PL14_16230	ENOG4108M1A	Chitin-binding protein
PL14_16235	ENOG4105CXY	transporter
PL14_16240	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
PL14_16250	ENOG4107FQX	Alpha-acetolactate decarboxylase
PL14_16255	ENOG4105C7K	acetolactate synthase
PL14_16265	ENOG4105C5H	ABC transporter
PL14_16280	ENOG4105CC0	LysR family Transcriptional regulator
PL14_16285	ENOG4105DAA	L-lactate
PL14_16290	ENOG4105DMF	Dehydrogenase
PL14_16305	ENOG4108V1U	phospholipid-binding protein
PL14_16310	ENOG4105IUQ	nucleoprotein polynucleotide-associated enzyme
PL14_16335	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
PL14_16340	ENOG4108RS6	transposase
PL14_16345	ENOG4105ETE	Transcriptional regulator (LacI family
PL14_16355	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
PL14_16360	ENOG4105DRS	transport system, permease
PL14_16375	ENOG41060NJ	transcriptional regulator
PL14_16380	ENOG4108KDD	Involved in the transport of maltose and maltodextrins (By similarity)
PL14_16400	ENOG4105E5W	Transporter
PL14_16405	ENOG4108NVR	Methyl-accepting chemotaxis
PL14_16410	ENOG4105DAN	ATP-dependent protease
PL14_16420	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
PL14_16445	ENOG4105ETE	Transcriptional regulator (LacI family
PL14_16450	ENOG4108RVA	ribokinase
PL14_16455	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
PL14_16460	ENOG4105CNN	ABC, transporter
PL14_16465	ENOG4105C2J	ABC transporter
PL14_16470	ENOG4105MRB	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity)
PL14_16485	ENOG410600T	transposase
PL14_16495	ENOG4108WC9	type VI secretion system effector, hcp1 family
PL14_16500	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
PL14_16505	ENOG4107RTM	4-alpha-glucanotransferase (EC 2.4.1.25)
PL14_16510	ENOG4107QQN	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
PL14_16515	ENOG41061ZR	Transcriptional regulator
PL14_16520	ENOG4108YYI	Protein of unknown function (DUF2810)
PL14_16525	ENOG4105C8Q	Methyl-accepting chemotaxis
PL14_16535	ENOG4105C8Q	Methyl-accepting chemotaxis
PL14_16540	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
PL14_16550	ENOG4107RGH	Aldehyde dehydrogenase
PL14_16555	ENOG4105EW9	transcriptional regulator AsnC family
PL14_16560	ENOG4105C8Q	Methyl-accepting chemotaxis
PL14_16570	ENOG4105CK7	Sodium proline symporter
PL14_16580	ENOG4105C26	Dehydrogenase
PL14_16595	ENOG4105E6M	Sulphatase-modifying factor protein
PL14_16605	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
PL14_16610	ENOG4107QZV	Type I secretion membrane fusion protein
PL14_16625	ENOG4108JJA	ABC, transporter
PL14_16635	ENOG4105BZU	Histidine kinase
PL14_16645	ENOG4105C8Q	Methyl-accepting chemotaxis
PL14_16650	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
PL14_16660	ENOG4105BZU	Histidine kinase
PL14_16665	ENOG4105C8Q	Methyl-accepting chemotaxis
PL14_16670	ENOG4108V3W	Chemotaxis protein, CheW
PL14_16675	ENOG4108V3W	Chemotaxis protein, CheW
PL14_16680	ENOG4105CBS	Chea signal transduction histidine kinase
PL14_16685	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
PL14_16695	ENOG4105E0I	Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) (By similarity)
PL14_16700	ENOG4107RUE	extracellular solute-binding protein family 1
PL14_16705	ENOG4106RMF	ParB family
PL14_16740	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
PL14_16745	ENOG4105C44	Serine transporter
PL14_16775	ENOG4105HEI	LysR family (Transcriptional regulator
PL14_16780	ENOG4108RYK	Nad-dependent epimerase dehydratase
PL14_16790	ENOG410901E	Membrane
PL14_16810	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
PL14_16815	ENOG4105D03	DNA-3-methyladenine glycosylase II
PL14_16835	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
PL14_16845	ENOG4105DR5	peptidase
PL14_16850	ENOG4105CTS	PTS system mannitol-specific
PL14_16855	ENOG4107SQ3	mannitol-1-phosphate 5-dehydrogenase
PL14_16860	ENOG4105E61	Mannitol repressor protein
PL14_16865	ENOG4105EP9	oxidoreductase
PL14_16870	ENOG4105DN9	Na H antiporter
PL14_16875	ENOG4105CK2	sodium dicarboxylate symporter
PL14_16880	ENOG4108VGI	doxx family
PL14_16900	ENOG4105J12	Multidrug resistance protein mdtN
PL14_16905	ENOG4108US0	Transcription regulator that can specifically activate or repress expression of target genes (By similarity)
PL14_16910	ENOG4108MJ5	VirK protein
PL14_16915	ENOG4105EXX	Deoxyribodipyrimidine photolyase-related protein
PL14_16920	ENOG41082J7	Rhodanese domain protein
PL14_16925	ENOG4107QWP	ABC-2 type transporter
PL14_16930	ENOG4105CJ1	ABC, transporter
PL14_16945	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
PL14_16955	ENOG4105F38	ABC transporter, permease
PL14_16975	ENOG4105C1J	atp-dependent rna helicase
PL14_16985	ENOG4107VXZ	Hydrolase
PL14_16995	ENOG41076CZ	activating enzyme
PL14_17000	ENOG4105G0K	glycine radical enzyme YjjI family
PL14_17010	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
PL14_17015	ENOG4108WUH	Transcriptional regulator, TetR family
PL14_17030	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
PL14_17040	ENOG4105D3G	Pseudouridine synthase
PL14_17095	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
PL14_17100	ENOG4108JUB	Transcriptional regulator
PL14_17125	ENOG4105CS6	Rhs element vgr protein
PL14_17175	ENOG4105C8P	)-transporter
PL14_17180	ENOG4108Q67	UPF0319 protein
PL14_17190	ENOG4105FDP	GntR family transcriptional regulator
PL14_17195	ENOG4105CZV	ABC transporter
PL14_17205	ENOG4105C8Q	Methyl-accepting chemotaxis
PL14_17225	ENOG4105EYK	Phosphatidylglycerophosphatase B
PL14_17230	ENOG4108UH6	UPF0754 membrane protein
PL14_17235	ENOG4105BZ1	(ABC) transporter
PL14_17245	ENOG4105BZU	Histidine kinase
PL14_17255	ENOG41064BZ	L-xylulose 5-phosphate 3-epimerase
PL14_17265	ENOG4108K4B	hydrolase
PL14_17300	ENOG4108KDD	Involved in the transport of maltose and maltodextrins (By similarity)
PL14_17315	ENOG4107FKK	extracellular solute-binding protein family 1
PL14_17325	ENOG4105CG3	alpha amylase, catalytic region
PL14_17335	ENOG4107QV7	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) (By similarity)
PL14_17365	ENOG4105D6U	Sodium Glutamate Symporter
PL14_17370	ENOG4105YE1	PilZ domain
PL14_17390	ENOG4105EFX	secretion protein, HlyD family
PL14_17395	ENOG4105KK7	inner membrane protein YiaW
PL14_17400	ENOG4106TD9	Diguanylate cyclase
PL14_17415	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
PL14_17420	ENOG4107SEY	Conserved Protein
PL14_17425	ENOG4108XDN	Transcriptional regulator
PL14_17430	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
PL14_17435	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
PL14_17445	ENOG4105C1J	atp-dependent rna helicase
PL14_17455	ENOG410600T	transposase
PL14_17485	ENOG4108M0H	Extracellular lipase
PL14_17490	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
PL14_17495	ENOG4107T9C	Alpha amylase catalytic region
PL14_17500	ENOG4107RGM	aldo keto reductase
PL14_17510	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
PL14_17515	ENOG4105D60	lipoprotein releasing system transmembrane protein
PL14_17535	ENOG4108VAC	response regulator
PL14_17550	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
PL14_17560	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
PL14_17565	ENOG4105BZU	Histidine kinase
PL14_17575	ENOG4105DVH	amino acid
PL14_17590	ENOG4105EJ7	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity)
PL14_17595	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
PL14_17605	ENOG4105BZU	Histidine kinase
PL14_17620	ENOG4107V40	secretion protein, HlyD family
PL14_17625	ENOG4108IJF	Heavy metal efflux pump, CzcA
PL14_17635	ENOG4107YWA	deoxycytidylate deaminase
PL14_17640	ENOG4105EE0	oxidoreductase
PL14_17645	ENOG4108UKZ	OsmC family
PL14_17650	ENOG4108UW5	maltose o-acetyltransferase
PL14_17665	ENOG4105DUM	transcriptional regulator, lysR family
PL14_17680	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
PL14_17685	ENOG4105MIR	Phenylalanine 4-monooxygenase
PL14_17690	ENOG41090A4	Pterin carbinolamine dehydratase
PL14_17695	ENOG4105C8Q	Methyl-accepting chemotaxis
PL14_17700	ENOG4105UQX	Mate efflux family protein
PL14_17705	ENOG4108AHD	Transcriptional regulator
PL14_17710	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
PL14_17715	ENOG4105BZU	Histidine kinase
PL14_17725	ENOG4105E5M	Multidrug resistance protein D
PL14_17735	ENOG4105R8A	Heat shock protein
PL14_17745	ENOG4105EW9	transcriptional regulator AsnC family
PL14_17750	ENOG4105KUU	lipolytic protein G-D-S-L family
PL14_17755	ENOG4106M3D	hemolysin
PL14_17760	ENOG4107IFA	Lipase (EC 3.1.1.3)
PL14_17770	ENOG4107G87	m6 family metalloprotease domain protein
PL14_17785	ENOG4105KXC	Collagenase
PL14_17800	ENOG4105DHS	permease protein
PL14_17805	ENOG4105CM4	permease protein
PL14_17810	ENOG4108IPW	abc transporter atp-binding protein
PL14_17815	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
PL14_17825	ENOG4107YB6	acetyltransferase, (GNAT) family
PL14_17830	ENOG4105DFI	Membrane
PL14_17835	ENOG4105EWV	Sodium calcium exchanger membrane region
PL14_17840	ENOG4105EE5	Membrane protein terC
PL14_17850	ENOG4105UG9	Antitoxin of the YafO-YafN toxin-antitoxin system
PL14_17875	ENOG4105M03	Domain of unknown function (DUF955)
PL14_17910	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
PL14_17915	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
PL14_17920	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
PL14_17930	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
PL14_17940	ENOG4107RAN	Peptidase, M16
PL14_17950	ENOG4105DM4	PTS System
PL14_17955	ENOG4105DE4	1-phosphofructokinase
PL14_17960	ENOG4105DTZ	bifunctional PTS system fructose-specific transporter subunit IIA HPr protein
PL14_17965	ENOG4107B7Y	DNA-binding transcriptional regulator FruR
PL14_17970	ENOG4107RFY	SbcCD D subunit
PL14_17975	ENOG4105EYH	Exonuclease
PL14_17980	ENOG4108MGY	Histidine kinase
PL14_17985	ENOG4107KBT	8-Amino-7-oxononanoate synthase
PL14_17995	ENOG4105CMQ	Chloride channel
PL14_18000	ENOG4105CKI	cobalamin synthesis protein
PL14_18005	ENOG4105C19	ABC transporter
PL14_18015	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
PL14_18030	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
PL14_18060	ENOG410787A	Pts system, glucitol sorbitol-specific
PL14_18065	ENOG4105DZY	Pts system, glucitol sorbitol-specific
PL14_18070	ENOG4105VI0	Pts system, glucitol sorbitol-specific
PL14_18075	ENOG4107QMF	Sorbitol-6-phosphate dehydrogenase
PL14_18080	ENOG4105J92	DNA-binding transcriptional activator GutM
PL14_18085	ENOG410804X	Transcriptional regulator
PL14_18090	ENOG410787A	Pts system, glucitol sorbitol-specific
PL14_18095	ENOG4105DZY	Pts system, glucitol sorbitol-specific
PL14_18100	ENOG4105VI0	Pts system, glucitol sorbitol-specific
PL14_18105	ENOG4108IJ9	(ABC) transporter
PL14_18115	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
PL14_18125	ENOG4107FKK	extracellular solute-binding protein family 1
PL14_18135	ENOG4105EG2	ABC transporter, permease
PL14_18160	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
PL14_18165	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
PL14_18175	ENOG4105CUW	cytochrome C-TYPE protein
PL14_18185	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
PL14_18200	ENOG4105BZU	Histidine kinase
PL14_18205	ENOG4105WH1	Two component transcriptional regulator luxr family
PL14_18210	ENOG4105CEE	C4-dicarboxylate transporter
PL14_18235	ENOG4105CVA	phosphate
PL14_18250	ENOG4105C1J	atp-dependent rna helicase
PL14_18320	ENOG4106CVF	DNA replication protein
PL14_18405	ENOG4105KUS	lysozyme
PL14_18435	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
PL14_18540	ENOG4105C22	threonyL-tRNA synthetase
PL14_18545	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
PL14_18550	ENOG41082NX	50s ribosomal protein l35
PL14_18555	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
PL14_18570	ENOG4108MIC	Mg-protoporphyrin IX methyl transferase
PL14_18605	ENOG410600T	transposase
PL14_18635	ENOG4105VXN	addiction module toxin, RelE StbE family
PL14_18670	ENOG4105VFU	Rna-binding protein
PL14_18835	ENOG410600T	transposase
PL14_18870	ENOG410600T	transposase
PL14_19005	ENOG4105QNF	Outer membrane lipoprotein
PL14_19010	ENOG410600T	transposase
PL14_19170	ENOG4108ZI4	Glyoxalase Bleomycin resistance protein (Dioxygenase
PL14_19180	ENOG4108ZI4	Glyoxalase Bleomycin resistance protein (Dioxygenase
PL14_19205	ENOG4105CC0	LysR family Transcriptional regulator
PL14_19280	ENOG4105KNA	-acetyltransferase
PL14_19285	ENOG410600T	transposase
PL14_19345	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
PL14_19355	ENOG4108RXX	maleylacetoacetate isomerase
PL14_19390	ENOG410600T	transposase